vvEPA
                                    United States
                                    Environmental Protection
                                    Agency
                                                           Solid Waste
                                                           Emergency Response
                                                           (5102W)
                 EPA 542-N-94-006
                 August 1994
                                         II
    The Applied Technologies Journal for Superfund Removals & Remedial Actions & RCRA Corrective Actions
    UNIQUE  MULTI-VENDOR  BIOREMEDIATION
    DEMONSTRATION BEGINS
    By James B. Harrington,
    New York State Department of Environmental Conservation
                                                                                  /fwri        ^\
                                                                                     H   voc's
                                                                                    ^^O  Bioremediation
                                                                                        Soil
                                                                                        Ground Water
    Three pilot-scale bipremediation studies
    are being conducted concurrently at the
    same site, the Sweden 3 - Chapman
    inactive hazardous waste site in the
    Town of Sweden, Monroe County,

               VI^ITT
       I M M U NOCHEM ISTRY
               1ISK5.ERT"
     VlSJTT &Q
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SITE  Subjects
 EX-SITU BIOREMEDIATION OF TNT,
 DINOSEB & OTHER  PESTICIDES/
 HERBICIDES
 By Wendy Davis-Hoover, Risk Reduction Engineering Laboratory
                                                             Pesticides,
                                                             Herbicides, TNT
The J. R. Simplot Ex-situ Anaerobic
Bioremediation System is a technology
designed to destroy nitroaromaric com-
pounds without forming any toxic inter-
mediates. The process can successfully
operate with bioreactor temperatures as
low as 18 degrees Centigrade, much
below optimum.  The EPA SITE
(Superfund Innovative Technology
Evaluation) Program has evaluated the
Simplot system's  destruction of the
herbicide, dinoseb (2-sec-butyl-4,6
dinitrophenol), at Bowers Field, an air-
port in Ellensburg, Washington with a
site contaminated! by crop dusters. The
SITE program has also evaluated the
destruction of TNT (2,4,6-trinitro-
toluene) at the Weldon Spring site in
St. Louis, Missouri.
  In the Bowers Field demonstration, the
Simplot process reduced the levels of
dinoseb by greater than 99.88%, to below
detection limits, from an  average pre-
   "
per kilogram (mg/kg) of feed soil. No
known toxic products were found in the
analysis of the post-treatment samples.
Other pesticides (nitroanaline,
malathion, atrizine and parathion)
were also reduced in the treated slurry.
  In the Weldon Spring demonstration,
TNT was reduced by greater than 95%
to below 1 ppm for most soil samples,
from an average pretreatment soil
 concentration of 1,500 ppm on a dry
 weight basis. No known toxic metabolites
 were seen; and, toxicity tests are ongoing.
   Usually under aerobic conditions,
 degradation of nitroaromatic compounds
 form products that are toxic.  However, the
 Simplot system treats contaminated soils
 (or liquids) using an anaerobic consortium
 of soil microorganisms. Anaerobic
 degradation of nitroaromatics takes place
 without,the formation of these toxic
 products.
   The J. R. Simplot technology mixes a
 carbon source with contaminated soil and
 then adds water and a phosphate buffer to
 create a buffered slurry. This prompts
 aerobic microorganisms to consume the
 carbon source and oxygen, thus lowering
 the redox potential of the slurry and
 creating anaerobic conditions. Anaerobic
 microorganisms then consume the tar-
 geted toxins present in the slurry.
   The mechanics of the process begin with
=excavatedisoM>eing'senrdirough-ar-" ~=™~
 vibrating screen to remove large rocks and
 other debris. The rocks and debris are
 washed to remove surface contamination.
 For the dinoseb process, this rinse water is
 combined with make-up water and added
 to the bioreactor.  (TNT is not very water
 soluble; thus, these rocks are treated in a
 different manner.)
   For both dinoseb and TNT, soil which
 has been seived is added to die bioreactor
with water to provide one liter of
water for each kg of soil to be treated.  •.
A phosphate buffer is added to the
system to control the pH to around 7
pH.  Batches of soil and potato starch
(2% by weight) are homogenized
together and added to the bioreactor
until the system is 75% full. According
to laboratory studies, optimum
conditions for dinoseb degradation are
temperatures of 30 and 35 degrees
Centigrade with a pH between 7 and
7.5-  The optimum temperature range
for TNT is also 30 and 35 degrees
Centigrade with an optimum
 pH of 6 to 7.
  The technology is suitable for soils
and liquids contaminated with
nitroaromatic compounds.  However,
the medium to be treated must be free
of toxic metals or any other com-
pounds that may be detrimental to the
appropriate microorganisms.
Report describing the complete dinoseb
demonstration and other pertinent
information will be available in the fall
of 1994. An Innovative Technology
Evaluation Report describing the TNT
demonstration will be available in the
winter of 1995-
  For more information call Wendy
Davis-Hoover at EPA's Risk Reduction
Engineering Laboratory at 513-569-7206.
DATA MANAGEMENT SYSTEM INTEGRATES SOFTWARE
FOR SUPERFUND SITES
By Richard G. Eilers, Risk Reduction Engineering Laboratory
Managers of Superfund sites and
Resource Conservation and Recovery
(RCRA) facilities now have a new tool to
assist in the graphical characterization and
data management at contaminated soil
and ground water sites. The GIS\Key™
Environmental Data Management
System is a software system that integrates
proven software under a single shell. This
integration allows database management
activities that would otherwise be more
difficult or costly to perform because it
singly meets needs typically requiring
multiple, independently run pieces of
software. The SITE (Superfund Inno-
vative Technology Evaluation) Program
evaluated GIS\Key™  because of its
  applicability to all Superfund sites. The
  system can meet industry needs and
  satisfy hazardous waste site reporting
  requirements for soil and ground water
  contaminants; but, it cannot manage
  ecological assessment or air pollutant data.
   The SITE evaluation assessed the
  software performance and accuracy of
  GIS\Key™ output. The GIS\Key™
  procedures were reviewed to ensure the
  data integrity, to evaluate general usability
  and to compare GIS\Key™ features to
  user requirements.
   Here are the strong points.  GIS\Key™
  facilitates the collection, reporting and
  analysis of site management data by
  producing a variety of site-specific tables,
 graphs and maps. The software can
 successfully generate four types of contour
 maps to assist in ground water mapping:
 (1) hydrogeologic maps; (2) chemical
 concentration isopleths; (3) geologic
 structure maps; and (4) geologic structure
 thickness isopach maps. With GIS\Key™ ,
 menu commands can yield several
 standard chemistry reports and con-
 struction and borehole summary tables.
 The system also can prepare well and
 borehole logs based on the information in
 the database. Among its capabilities are
 geologic cross sections, boring logs,
 potentiometric maps, isopleth maps,
 structure maps, summary  tables,
 Software continued on page 4

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xvEPA
The Need
                    United States      r "  :  " Environmental Monitoring    January 1994
                    Environmental Protection    Systems Laboratory        I
                    Agency          .      P.O. Box 93478          f
                                        Las Vegas NV 89193-3478
                   OFFICE OF RESEARCH AND DEVELOPMENT
                                                          TECHNOLOGY SUPPORT PROJECT
                     Immunpchemical  Analysis
                     Of Environmental       j
                     Samples
                       Innovative
                     Technology
                       s  , *v } g ^ » .' fa.ys">-jgjsjj
                                  \   ?
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The Use
 The Environmental
 Monitoring Systems
 Laboratory - Las Vegas
 (EMSL-LV) is pioneer-
 ing an investigation into
 the usefulness of
 immunochemical
 techniques for monitor-
 ing the extent of con-
 tamination in environ-
 mental and biological
 matrices.  EMSL-LV
 has developed and
 demonstrated several
 of these techniques and
 believes that they hold
 great promise for the
 quantitative analysis of
 target analytes for use
 in ground-water surveil-
 lance,  in situ hazardous
 waste  site monitoring,
 and assessment of
 human exposure.
 Current work involves
 the analysis of chemi-
 cals like PCBs,
 nitroaromatics, and
""certainpeBtrcides'that —
 are difficult to analyze
 by other analytical
  methods. EMSL-LV
  has sponsored two
  national meetings that
  focused on  regulatory
  issues and technologi-
  cal advances in envi-
  ronmental immuno-
  chemistry.  These
  meetings brought
  together government,
  industry, and university
  scientists to discuss
  problems of mutual
  interest in the field.

  A  1993 Technology
  Support Center project
  at a Superfund  site in
  Region 5 demonstrated
  the usefulness of
  immunochemical
  methods for screening
   PCBs in soil and river
  sediment.  This project
 was an example of
 cooperation between
 EPA, DOE, the state of
 Michigan, and various
 contractors. Two
 immunoassays and a
 chloride-ion specific
 electrode were used on
 site and the real-time
 analytical results were
 compared with stan-
 dard GC results from
 EPA method 8081.
 Preliminary results
 show good agreement  ,
 between the immuno-
 assays and GC and
 even stronger correla-
 tion could be achieved
 with tighter quality
 control measures.

 In addition, other EPA
 offices have applied
 immunochemistry for
 screening and analysis
 in their programs. The
 Office pf Water has
" "usedlmmunoassays to
  screen indirect discharges
  of specific analytes for
  permitting under the
  Clean Water Act
  (304h). Sample analy-
  sis data may soon be
  used for comparison
  and compliance moni-
  toring within selected
  industries, such as
  commercial laundries.
  The Office of Pesticides
  is looking at ways to
  shorten the pesticide
  registration process  by"
  using immunochemistry
  as a cost-effective
  technology.

  Other government
  agencies and universi-
  ties are studying immu-
  nochemical methods.
  The Food and Drug
  Administration (FDA)
may use immunoas-
says to obtain data for
the calculation of safe
concentrations of
residues.  A recent
university project used
immunoassays to track
contamination during
the 1993 Midwestern
flood. In applications
as diverse as organic
geochemistry and
military operations,
immunochemical
methods have been
 used for volatile organic
compound measure-
 ment. The U.S. Depart-
 ment of Agriculture
 (USDA) is integrating
 immunoassays into
 rapid test procedures
 for detection of resi-
 dues in meat and
 poultry. Results from
 these tests will be used
 in regulatory and
 compliance programs
- for veterinary "drugs; ~-^-
 sanitation, and pest
 control. The National
 Institute for Occupa-
 tional Safety and Health
 (NIOSH) has applied
 immunoassays to
 herbicide research,
 clinical analysis,
 biomarkers, and im-
 mune  biomonitoring.
 They use the methods
 to detect morphine
 factor, alachlor, atr-
  azine, cyanazine,
  metalachlor, and 2,4-D.
  State  laboratories have
  analyzed soil samples
  and water from private
  wells using immuno-
  chemical test systems
  for triazine (atrazine)
  samples.

  The results of EPA's
  Superfund Innovative
  Technology Evaluation

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 The Use
 (continued)
 The Limits
The Status
 (SITE) studfes indicate
 a strong correlation
 between field immuno-
 assays, laboratory
 immunoassays, and
 gas chromatography-
 mass spectrpmetry.
            I
 Another field use of
 immunochemistry that
  is being explored at
  EMSL-LV, the personal
  exposure monitor
  (PEM), may revolution-
  ize safety and exposure
  requirements for work-
  ers who deal with
  hazardous chemicals.
  Immunochemical
  dosimeter badges can
  be used to detect
  pentachlorophenol and
  nitroaromatics, and are
  being developed for
  parathion and
  chloropyrifos. These
  badges are lightweight,
  inexpensive, quick, and
  provide a real time
  indication of exposure.
                      The use of immuno-
                      chemical techniques is
                      gaining acceptance in
                      the environmental
                      sciences. One need
                      that is being addressed
                      is that of specificity.
                      Frequently, immunoas-
                      says are available for a
                      class of compounds,
                      IlkePCBs.  Specific
                      quantitation for each
                      component Has been
                      difficult.     !
                                 I
                      The development of
                      PEMs, for exbrnple,
                        must address the
                        question of diffusion of
                        chemicals through a'
                        semipermeable mem-
                        brane, the optimum
                        concentration of the
                        antibody, detection
                        limits of the PEM and
                        quantitation by immu-
                        noassay, the efficiency
                        of the antibody in
                        capturing the analyte,
                        and the capacity of the
                        device.            [

                        Validation studies of,
                        reproducibility, matrix
                         effects, field trials, false
                         negatives/positives,
                         and correlation with
                         other tests will assist
                         acceptance of immuno-
                         chemical methods at
                         Superfund and RCRA
                         sites. The legal defensi-
                         bility of immunochemi-
                         cal results is yet to be
                         determined.

                         Advantages and limita-
                         tions are summarized
                         below.
                       Advantages
                       • Field portable
                       • User frienjdly
                                Ji
                       • Quick and inexpensive

                       • Potential lor wide range of
                        analytes i

                       • Useful forjmany matrices

                       • Low detection limits
                                  Limitations
                                   • Separate  immunoassay needed
                                    for each analyte

                                   • More cpmplex analysis required
                                    for quantitation of specific
                                    analytes

                                   • Long development time for new
                                    antibodies and methods
One new avenue of
investigation is the use
of antibody-cpated,
fiber-optic imrnuno-
sensors. Another
application is the
integration of1 robotics
capability for ihigh
sample throughput and
the development of a
tiered analytical ap-   ',
proach, i.e., biological
and environmental
samples, biomarkers,
target analytes, and
degradation products.
This system of analyti-
cal procedures will
enable scientists to
measure contamina-
tion at the source,
follow the fate and
transport of residual
amounts, and assess
 (continued on next page)

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The Status
(Continued)
 References
human exposure.
Multianalyte immunoas-
says that can identify
several analytes are
expected to expand the
desirability of immuno-
assay technology for
environmental use.
Work in this area is
already underway at
EMSL-LV and else-
where. Other applica-
tions of immuno-
chemistry, such as
multianalyte optical
immunobiosensors and
biorefractometry, are
being developed.

Industry recently
formed the Analytical
Environmental Immuno-
chemistry Consortium
(AEIC), which is focus-
sing on performance-
based method guide-
lines, method valida-
tion, and formation of
consensus on regula-
tory and technological
issues. The National
Technology Transfer
Center (NTTC) offers a
vehicle for collaborative
studies. Cooperative
Research and Develop-
ment Agreements
(CRADAs) between
industry and the gov-
ernment can be used to
promote technology
development and
licensing of irnmuno- .
chemical applications.
The EMSL-LV has a
Technology Transfer
Office that is able to
coordinate CRADAs for
the development of
immunochemical
methods.    	
 Immunochemical
 Methods for Environ-
 mental Analysis,
 J. M. Van Emon and
 Mumma, R. O., eds.
 ACS Symposium
 Series 442, Washing-
 ton, DC, 1990, 229pp.
 Immunochemistry
 Summit Meeting II,
 C. L. Gerlach and
 D. A. Fuccillo, report-
 ers. September 1-2,
 1993, Las Vegas, NV.
 Internal Report to
 EMSL-LV.
 Immunochemical
 Methods for Environ-
 mental Analysis,
 J. M. Van Emon and
 V. Lopez-Avila, Anal.
 Chem., Vol. 64, No. 2,
 1992.
                        For further Information about the immunochemistry program at the EMSL-LV,
                        contact:
                       • Dr. Jeanette Van Emon-„,„«,—,— —— —-- -*-•
                        U.S. Environmental Protection Agency         ^
                        Environmental Monitoring Systems Laboratory
                        P.O. Box 93478
                        Las Vegas, NV 89193-3478
                        (702)798-2154

                        For information about using immunochemical methods at a Superfund or
                        RCRA site through the EMSL-LV Technology Support Center, contact:

                         Mr. Ken Brown, Director
                         Technology Support Center
                         U.S. Environmental Protection Agency
                         Environmental Monitoring Systems Laboratory
                         P.O. Box 93478
                         Las Vegas, NV 89193-3478
                         (702) 798-2270

                         For information about the Technology Transfer Office at the EMSL-LV,
                         contact:

                         Mr. Eric Koglin
                         U. S. Environmental Protection Agency
                         Environmental Monitoring Systems Laboratory
                         P.O. Box 93478
                         Las Vegas, NV 89193-3478
                         (702) 798-2432

                         The Technology Support Center fact sheet series 14 developed by
                         Clare L. Gerlach, Lockheed Environmental Systems & Technologies Company, Las Vegas

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                                                                                                   Partners
   REQUEST  FOR  INFORMATION ON
   INNOVATIVE MIXED RADIOACTIVE  AND
   HAZARDOUS WASTE TECHNOLOGIES
   The U.S. Environmental Protection
   Agency (EPA) and the Departments of
   Energy (DOE), Interior and Defense, in
   conjunction with the Western Governors
   Association (WGA), are interested in
   information about innovative mixed
   radioactive and hazardous waste reme-
   diation technologies. The DOE is the lead
   Federal agency for the request for
   information. Below is a description of the
   specific information diat is requested,
  followed by a description of die activities
  of the Federal government/WGA
  partnership.
    DOE's Office of Environmental
  Management has been soliciting infor-
  mation from commercial companies and
  technology developers interested in dem-
  onstrating new and innovative technologies
  to accelerate die identification, treatment,
  remediation, storage or disposal of mixed
  radioactive and hazardous waste at Federal
  facilities in the western United States. The
  date set for interested parties to submit de-
  scriptions of specific cleanup technologies
  was September 30, 1994.
   Submissions are to describe technologies
  which aid in die cleanup of high-level,
  transuranic or low-level mixed waste and
  facilitate the environmental restoration of
  contaminated soils, buried waste drums
 and/or ground water. The technology
   description, limited to five pages, addresses
   the following issues: (1) ability to alleviate
   risks to public health and safety and to the
   environment; (2) capacity for public
   acceptance; (3) potential permitting and
   regulatory barriers; (4) extent of private
   sector and multi-agency involvement;
   (5) potential for technology transfer or
   commercialization; (6) likelihood of
   successful demonstration, including an
   assessment of technical risks; (7) capacity
   for volume reduction of hazardous and
   radioactive components; (8) viability of
   final waste forms and treated secondary
   waste forms to gain public acceptance, be
   relatively stable and meet regulatory
   criteria; (9) magnitude of recycling and
  material recovery potential; and
  (10) ease of implementation to full scale
  initiative.
    Information was to be submitted to
  Dr. George Coyle, Office of Technology
  Development, EM-50, U.S .Department
  of Energy, 1000 Independence Avenue
  S.W., Room 5B-104, Washington, DC
  20585 or faxed to 202-586-6773.
   Based on the technology descriptions
  received by DOE, a formal Request for
  Proposal may be issued to focus on specific
  needs and site characteristics.  DOE's
  formal notice of request for information,
  published in the FEDERAL REGISTER
   on June 2,1994, is pursuant with the
   activities of the Federal Advisory
   Committee to Develop On-site Innovative
   Technologies (DOIT) Committee. The
   formation of the DOIT Committee, a
   fact-finding advisory group, is the result of
   the signing of a Memorandum of
   Understanding (MOU) among the
   Secretaries of the Departments of Defense,
   Energy and the Interior; the Administrator
   of EPA; and the Western Governors
  Association. The purpose of the MOU is
   to est£iblish a more cooperative approach to
   the development of technical solutions to
  environmental restoration and waste
  management problems shared by states,
  commercial entities and the Federal
 . Government.  It is hoped that the regional
  approach will serve as a demonstration of
  principles and practices which may be
  adopted nationally.
   In addition to identifying improved
  and innovative cleanup technologies,
- the DOIT Committee attempts to address
  all die issues needed for successful
  technology development and transfer,
  including: regulatory and institutional
  barriers; worker training and education;
 technical and financial needs and
 requirements; commercialization issues,
 procurement; and public and stakeholder
 participation.
 Multi-Vendor continued from page 1

 a negative pressure stripping reactor, an
 in-situ bioreactor and an above-ground
 vapor-phase bioreactor. This process
 focuses on removing volatile contam-
 inants out of the soil above the water table
 as well as volatile contaminants in the
 ground water.  The contaminants are then
 treated biologically. The second process
 utilizes bioventing technology where
 injection and extraction wells will allow the
 vendor to regulate oxygen and nutrient
 levels to stimulate the native bacteria in the
 soil into biodegrading the contaminants of
 concern. The third process is based upon
 die construction of two identical biovaults.
 Contaminated soils are placed in each
biovault where nutrient, moisture and
oxygen levels can be controlled. The first
biovault is operated under aerobic
conditions. The second biovault is
 operated back and forth between aerobic
 and anaerobic conditions.
  These MVTD pilot-scale demonstrations
 will not .interfere widi on-going remedi-
 ation at the site, where approximately 2,500
 drums of hazardous waste and grossly
 contaminated soil have already been re-
 moved. The Record of Decision, signed in
 March 1994, specified excavation of
 contaminated soil  widi on-site treatment
 via LowTemperature'Thermal Desorption;
 limited ground water remediation is also
 specified. If the MVTD project is suc-
 cessful, diese technologies will be used to
 remediate the remaining contamination at
 die site.
  The three vendors for the MVTD were
chosen through a competitive process.
Thirteen technical  proposals were sub-
mitted in response  to a formal Request for
 Proposal. After a review of diose proposals,
 nine technology vendors were invited to
 submit bids. The three vendors selected
 began field work in July 1994.
  The I'JYS Center coordinated die
 development of the protocol that was the
 centerpiece of the Requests for Proposals
 and wil] be on-site to document vendor
 progress and provide sample collection
 assistant.  The SITE program will
 provide sample collection and analytical
 services, sampling protocol development
 and project reports.  The NYSDEC
 developed the project and is leading it,
 providing management and funding for
 die treatment vendors and construction
support services necessary to implement
die study.
  For more information, call Jim Harrington
at NYSDEC at 518-485-8792.

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    hydrographs, chemical time series
    graphs, tables and other maps and line
    graphs that meet reporting require-
    ments.
      GIS\Key™ site maps typically start
    with digitized basemaps, including
    U.S. Geological Survey 7.5 minute
    quadrangle maps, to provide general
     topography and features such as
     streets, highways, schools and bodies
     of water. Site-specific features such as
     buildings and waste management units
     are then added.  Project maps for
     Resource Conservation and Recovery
     Act (RCRA) hazardous waste facilities
     and Comprehensive Environmental
     Response, Compensation and Liability
     Act (CERCLA)  sites are stored inside
     the regional basemaps and act as the
     visual starting points from which users
     can obtain specific chemical, geologic
     and hydrologic  data for each map
     point. Environmental data for a
     project-chemical, geological and
     hydrological-are stored in the
     GIS\Key™ database.  GIS\Key™
     improves overall project data quality
\
module reviews chemical laboratory
quality control data and parameters,
checks site data against historical ranges
and generates exception reports.
Sample locations that provide values
which fail QC objectives are visually
indicated to the user and thus help to
avoid the use of suspect data in maps
and reports. The geology module
includes Ethology, user-defined
formations and blow counts. The
hydrology module includes derived
aquifer parameters such as verticle and
horizontal permeability. The database is
linked to the  other component of the
geographical information system,
GIS\Graphics.  Data can be entered
 into the database either manually or
 electronically.
   GIS\Key™  provides several editable
 reference lists, including a list of
 regulatory thresholds, test methods,
 chemical names, aliases and registry
 numbers. GIS\Key™ produces
 presentation quality graphics that are
 designed to be included directly into
 reports. The maps, sections and
to modify or enhance graphic output.
  GIS\Key™ does not require
specialized computer skills, but some
specialized AutoCAD®, electronic data
transfer and database management
system skills are needed to make full use
of it.  TheGIS\Key™ system is
compatible with 386 and 486 micro-
computers and runs oh standard DOS
and local area networks.  The
GIS\Key™  database menu provides
commands for  electronic database
import and export; and, data subsets
can be exported in a format compatible
with EPA GRITS/STAT to conduct
statistical routines that conform
 to RCRA guidelines.
  For more information, call Richard Eilers
 at EPA s Risk Reduction Engineering  ,
 Laboratory at 513-569-7809. An     •;  ,
 Innovative Technology Evaluation Report
 (Document No.  EPA/540/R-94/505) and a
 Site Technology Capsule (Document No.
 EPA/540/SR-94/505) describing detailed
 results of the evaluation can be ordered by
 calling the Center for Research and
 Environmental Information (CERI) at 513-
                               OH 45242-0419. Please refer to the document number on the cover of the issue if available.

                 Tech Trends welcomes readers' comments and contributions. Address correspondence to: Managing Editor Tech Trends (5102W)
                                 U.S. Environmental Protection Agency, 401 M Street, S.W., Washington, DC 20460
       United States
       Environmental Protection Agency
       National Center for Environmental
       Publications and Information
       P.O. Box 42419
       Cincinnati, OH 45242-0419

       Offical Business
       Penalty for Private Use S300

       EPA 542-N-94-006

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