United States
             Environmental Protectior
             Agency
             Municipal Environmental Research
             Laboratory   '  " *
             Cincinnati OH 45268
EPA-600/2-79-163
December 1979
             Research and Development
vvEPA
Investigations of
Biodegradability and
Toxicity of Organic
Compounds

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                RESEARCH REPORTING SERIES

Research reports of the Office of Research and Development, U.S. Environmental
Protection Agency, have been grouped into nine series. These nine broad cate-
gories were established to facilitate further development and application of en-
vironmental technology. Elimination of traditional grouping was consciously
planned to foster technology transfer and a maximum interface in related fields.
The nine series are:

      1.  Environmental Health  Effects Research
      2.  Environmental Protection Technology
      3.  Ecological Research
      4.  Environmental Monitoring
      5.  Socioeconomic Environmental Studies
      6.  Scientific and Technical Assessment Reports (STAR)
      7.  Interagency Energy-Environment Research and Development
      8.  "Special" Reports
      9.  Miscellaneous Reports

This report has  been assigned  to the ENVIRONMENTAL PROTECTION TECH-
NOLOGY series. This series describes research  performed to develop and dem-
onstrate instrumentation, equipment, and methodology to repair or prevent en-
vironmental degradation from point and non-point sources of pollution. This work
provides the new or improved technology required for the control and treatment
of pollution-sources to meet environmental quality standards.
This document is available to the public through the National Technical Informa-
tion Service, Springfield, Virginia 22161.

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                                                    EPA-600/2-79-163
                                                    December 1979
INVESTIGATIONS OF BIODEGRADABILITY AND TOXICITY OF ORGANIC COMPOUNDS
                                 by

                           Jan R. Dojlido
            Institute of Meteorology and Water Management..
              Department of Water Chemistry and Biology
                           Warsaw, Poland
                       Grant No. PR-05-532-15
                           Project Officer

                           Robert L. Bunch
                    Wastewater Research Division
             Municipal Environmental Research Laboratory
                       Cincinnati, Ohio  45268
             MUNICIPAL ENVIRONMENTAL RESEARCH LABORATORY
                 OFFICE OF RESEARCH AND DEVELOPMENT
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                       CINCINNATI, OHIO  45268
                   &ms&^si Protection

                               Street
                            60804

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                                 DISCLAIMER
     This report has been reviewed by the Municipal Environmental Research
Laboratory, U.S. Environmental Protection Agency, and approved for publication,
Approval does not signify that the contents necessarily reflect the views and
policies of the U.S. Environmental Protection Agency, nor does mention of
trade names or commercial products constitute endorsement or recommendation
for use.
                                    ii

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                                  FOREWORD


     The Environmental Protection Agency was created because of increasing
public and government concern about the dangers of pollution to the health
and welfare of the American people.  Noxious air, foul water, and spoiled
land are tragic testimony to the deterioration of our natural environment.
The complexity of that environment and the interplay between its components
require a concentrated and integrated attack on the problem.

     Research and development is that necessary first step in problem solu-
tion, and it involves defining the problem, measuring its impact, and
searching for solutions.  The Municipal Environmental Research Laboratory
develops new and improved technology and systems for the prevention, treat-
ment, and management of wastewater and solid and hazardous waste pollutant
discharges from municipal and community sources, for the preservation and
treatment of public drinking water supplies, and to minimize the adverse
economic, social, health, and aesthetic effects of pollution.  This publica-
tion is one of the products of that research; a most vital communications
link between the researcher and the user community.

     Increasing numbers of products of commerce are reaching waste disposal
facilities, and little is known concerning their effects on treatment.  Some
of these compounds are toxic, and others have profound physiological effects.
The future dictates that all compounds reaching our surface waters should
be biodegradable.  Knowledge of what compounds that are not biodegradable
will aid us in logically planning what changes we should make to eliminate
them or develop treatment processes that will remove them.

     This report presents the results of a testing program of several organic
compounds for toxicity and treatability.
                                        Francis T. Mayo
                                        Director, Municipal Environmental
                                          Research Laboratory
                                     111

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                                   PREFACE


     This project was conducted within the frame of the Marie SkJrodowska
Curie Fund, a bilateral monetary arrangement for cooperative scientific
programs between Poland and USA.

     This final report is a concise summary of four interim reports.  The
interim reports were not published but are on file in the libraries of
Institute of Meteorology and Water Management, 01-673, Warsaw ul.  Podlesna 61,
Poland and U.S. Environmental Protection Agency, Environmental Research
Center, Cincinnati, Ohio 45268.   The interim reports, date and subject matter
are:

          Report #1, January, 1976 - MEK
          Report #2, November, 1976 - MEK, DMF and DMA
          Report #3, February, 1978, - PNP, OCP, TCP, and DCDEE
          Report #4, June,  1979 - Five FWAs

     The various sections of this report were prepared by the following
authors:

          Principal Investigator   - Jan R. Dojlido,  Ph.D.
          Biodegradability Testing - Andrzej  Stojda
                                   - Elzbieta Gantz
                                   - Jan Kowalski
          Analytical Methods       - Halina Bierwagen
          Toxicity Testing         - J6zef Wojcik, Ph.D.
                                   - Bozena Slomczyriska
                                   - Anna Gwiazdowska
                                     IV

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                                  ABSTRACT


     The biodegradability and toxicity of twelve organic compounds were
investigated.   They were:

          methylethyl ketone (MEK)
          dimethyl amine (DMA)
          dimethyl formamide (DMF)
          p-nitrophenol  (PNP)
          o-chlorophenol (OCP)
          trichlorophenol (TCP)
          dichlorodiethyl ether (DCDEE)
          five various fluorescent whitening agents, all of the same
            stilbene-cyanuric type, but with different substitutes (FWA).

     The investigations  of the biodegradability were carried out by three
methods, namely:   (1) respirometric measurements, (2) tests in the river
water, and  (3) laboratory activated sludge units.

     MEK, DMA, DMF, PNP, OCP, TCP were all biodegradable.  DCDEE was found to
be a biologically  inert  substance under conditions of the tests.  DCDEE is
a volatile  substance; therefore,  it may be partially blown off in the  aeration
chamber.  The FWA's are  fairly resistant  to biodegradation; however, they do
not affect  the overall treatability of wastewater.

     Long term respirometric measurements using  a "Sapromat" that prints out
the amount  of oxygen uptake  every hour was very  useful  in supplying data for
kinetic  parameters and inhibiting effects of various compounds.   The acti-
vated  sludge tests gave  overall treatability information and time required
for acclimatization.

     The toxicities of the  test substances were  determined by bioassays
using  fish  Lebistes reticulatus and Daphnia magna.   The toxicity  of MEK, DMF,
TCP are  low while  PNP, OCP,  TCP were  fairly high to  fish.  The  FWA's varied
from  low to high  toxicity to fish depending on  the molecular structure.

     The work has  been  accomplished within  the  Polish American  agreement
Project  PL-480, Grant  PR-05-532-15 by the Institute  of  Meteorology and Water
Management, Department  of Water Chemistry and  Biology at Warsaw,  Poland,  for
the U.S. Environmental  Protection Agency.

      The work was  finished  in  1979.

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                             CONTENTS

Foreword
Preface  ................. ............   1V
Abstract .............................
Figures  .............................
                                                                    vi ^
Tables ..............................    .
Symbols  ....... ......................  X1V
                                                                    YV1
Acknowledgements ............. ............
         \
   1.  Introduction   ...... .................    *
   2.  Conclusions ........ ................    ^
   3.  Recommendations ......................    ~
   4.  Background Information   ..................    11
   5.  Experimental Procedures  ..................    17
          Respirometric Measurements  ...............    •*•'
          River Model  ......................    18
          Treatability Tests  .  ..................    18
          Toxicity Tests  .....................    20
          Supplementary Experiments   ...............    21
          Analytical  Procedures   .................    22
   6.  Methods of Calculations  ..................    25
          Respirometric Data  ...................    25
          Biodegradability  in River Water   ............    31
          Treatability Data  ...................    31
          Toxicity Tests  .....................    33
          Supplementary Tests   ..................    33
   7.  Results of Biodegradation .................    35
          Methylethyl Ketone, MEK   ................    35
          Dimethyl Amine, DMA  ..................    38
          Dimethyl Formamide, DMF   ................    45
          Para-nitrophenol, PNP  .................    50
          Ortho-chlorophenol, OCP   ................    55
          Trichlorophenol,  TCP  ..................    61
          Dichlorodiethyl Ether, DCDEE ..............    66
          Fluorescent Whitening Agents,  FWAs ...........    71
   8.  The  Results of Bioassays  .................    84
          Methylethyl Ketone, MEK  ................    84
          Dimethyl Amine, DMA  ..................    85
          Dimethyl Formamide, DMF   ................    86
          Para-nitrophenol, PNP  .................    86
          Ortho-chlorophenol, OCP   ................    87
          Trichlorophenol,  TCP  ..................    89
          Dichlorodiethyl Ether, DCDEE ..............    89
          Fluorescent Whitening Agents,  FWAs ...........    90
 References  ............................    94

                                  vii

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        initial  concentration of the tested substance c
                                                       o
15   The curves from Figure 14 after linearizing transformation .  .

16   The final carbonaceous BOD L  as function of
                                   FIGURES

Number

  1   Laboratory activated sludge unit 	    19

  2   Typical shape of BOD curve of a solution containing
        nutrient medium and a specific organic compound  	    25

  3   The typical BOD curve transformed by equation
        z = log dy/dt	       27

  4   The dependence of final carbonaceous BOD L  on the
                                                                          29
  5    The  typical  curve  of the decomposition of a specific
        organic  compound in river water  	             32

  6    The  final  carbonaceous BOD  Lc  as  a  function of
        initial  MEK  content c  .  .                                         ,c
                             o       	     o«>
                                                                          36
 7   Lag phase duration At-^ as function of CQ	

 8   Dependence of the ratio r on the initial MEK
       concentration c	                                        ,,-
                      o     	    36

 9   Decrease of BOD and MEK during the respirometric test  	    36

10   Linearized BOD curve from Figure 9	                36

11   The decomposition of MEK in river water	          37

12   MEK removal by activated sludge  .  .	              38

13   The treatability coefficient K    of wastewater
       containing MEK	LUU                                   _0
                                    	«	    jo

14   BOD curve,  DMA decrease and NH% increase during
       the respirometric test  .  . ."	                     39
                                                                         39
       initial DMA content c0 .  .c	               40
                                    Vlll

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Number
 17   The influence of the seed acclimatization on the                   ^
        DMA biodegradation process  	

 18   The inhibition time of glucose decomposition Ati and of
        DMA decomposition At2 as function of the DMA initial	    ^
        content c   	

 19   The dependence of the ratio r on the initial DMA               ^    ^
        concentration CQ   	
                                                                         42
 20   The decomposition of DMA  in river water  	
                                                                         43
 21   DMA removal  by activated  sludge  	

  22   The treatability  coefficient  KCQD of wastewater           ^        ^
         containing DMA   	
  23   BOD curve,  DMF decrease and NH3 increase during the                ^
         respirometric test  	

  24   The curve from Figure 23 after linearizing transformation ...    45

  25   The final carbonaceous BOD L  and the final ammonia
         content as a function of initial DMF content CQ  	

  26   The influence of the seed acclimatization on the                   ^
         DMF biodegradation process   	

  27   The inhibition time of glucose decomposition Atj_ and
         of DMF decomposition At2 as  a function of the DMF
         initial content CQ	•  '

  28   The dependence of the ratio r  on  the  initial DMF                   ^
         concentration  c    	

  29   The decomposition of DMF  in river water	    48

  30   DMF removal  by activated  sludge  	

  31   The treatability coefficient  KCQD of wastewater                   ^
          containing DMF  	
   32   BOD curve and PNP decrease during the respirometric test  ...     51

   33   The curves from Figure 32 after linearizing transformation  .  .     51

   34   The final carbonaceous BOD LC as a function of
          initial PNP content CQ	     51
                                        IX

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Number

 35   The influence of the seed acclimatization on the
        PNP biodegradation process  .................     52

 36   The inhibition time of glucose decomposition Atj_ and
        of PNP decomposition At2 as a function of the PNP
        initial content c   .....................     52

 37   The dependence of the ratio r on the initial PNP
        concentration c
                       o            .................

 38   The decomposition of PNP in river water ............     54

 39   PNP removal by the activated sludge ..............     55

 40   BOD curves of nutrient medium with various concentrations
        of OCP  ...........................     56
41   The final carbonaceous BOD L  as a function of initial
                    o
        OCP content c
 42   The inhibition time of yeast  extract decomposition Atj
        as a function of the initial  OCP content  c  .........     57

 43   The OCP content decrease during the respirometric test  ....     57

 44   The decomposition of OCP in river water ............     58

 45   Overall treatability and OCP  removal by activated sludge  ...     60

 46   BOD curves  of nutrient medium with various  concentrations
        of TCP  ...........................     62

 47   The final carbonaceous BOD  L  as  a function of initial
        TCP content c   ..... ? .................     62

 48   The TCP content decrease at the initial concentration
        12 mg/1 TCP .........................     63

 49   The influence of adaptation on  BOD process  in  the
        samples containing 10 mg/1  TCP   ...............     63

 50   The decomposition of TCP in river water ............     65

 51   Overall  treatability and TCP  removal  by activated sludge  ...     66

 52   BOD curve of  the  sample containing DCDEE  ...........     67

 53   Final  carbonaceous  BOD L as  a  function of  initial
        DCDEE  content c    .  .  ?                    •                       AT
                       o   ......................     o/

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Number
54
55
56
57

58

59

60

61

62

63

64

65

66
67
68
69
70
71
72
73
74
75
76

DCDEE changes in river water 	 	
Nitrites and ammonia changes in river water 	
The volatility of DCDEE from aqueous solution 	
DCDEE concentration in the effluent from activated
sludge unit 	
BOD curves of the samples containing nutrient medium
and 100 mg/1 of various FWAs .... 	
The curve of activated sludge endogenous respiration
in the presence of FWA-1 	
The curves of activated sludge endogenous respiration
in the presence of FWA-3 	
Photolytic FWA-1 decomposition in river and
distilled water 	
Photolytic FWA-2 decomposition in river and
distilled water . . 	 	
Photolytic FWA-3 decomposition in river and
distilled water 	
Photolytic FWA-4 decomposition in river and
distilled water 	
Photolytic FWA-5 decomposition in river and
distilled water 	
The mortality of fish at various MEK concentrations 	
The mortality of fish at various DMF concentrations 	
The mortality of fish at various PNP concentrations 	
The mortality of fish at various OCP concentrations 	
The mortality of fish at various TCP concentrations 	
The mortality of fish at various DCDEE concentrations 	
The mortality of fish at various FWA-1 concentrations 	
The mortality of fish at various FWA-2 concentrations 	
The mortality of fish at various FWA-3 concentrations 	
The mortality of fish at various FWA-4 concentrations 	
The mortality of fish at various FWA-5 concentrations 	
Page
68
69
70

70

72

72

73

76

76

76

77

77
84
87
88
88
89
90
91
91
92
93
93
XI

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                                   TABLES

Number                                                                   Page

  1   The Respirometric Data	      3

  2   The Decomposition of Substances in River Water 	      4

  3   Photolytic FWAs Decomposition in Water (Light
        Intensity 1000 Lux)   	      5

  4   Treatability of the Tested Substances by Activated Sludge  ...      5

  5   Lethal Concentrations  of the Tested Substances to
        Lebistes reticulatus and Daphnia magna 	      6

  6   The Conditions of Respirometric Measurements of
        DMA Biodegradability 	     38

  7   Kinetic Parameters of  DMA Biodegradation in River Water  ....     42

  8   The Course of Activated Sludge Acclimatization to DMA  .....     44

  9   The Conditions of the  Respirometric Measurements  of
        DMF Biodegradation	     44

 10   The Conditions of Respirometric Measurements of
        PNP Biodegradability 	     45

 11   Kinetic Parameters of  PNP Biodegradation in River Water  ....     54

 12   The Conditions of the  Tests Made by Means of Sapromat  	     56

 13   Kinetic Parameters of  OCP Biodegradation in River Water  ....     59

 14   Conditions of Respirometric Measurements of
        TCP Biodegradability 	     61

 15   BOD Process in the Samples Containing Various
        TCP Concentrations	     62

 16   The Initial and Final  DCDEE Content and  NO   and NO
        Increase During the  Tests in Sapromat  (tRe First Series)  ...     67
                                     Xil

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Number                                                                  Pa§e

 17   The Final FWAs Concentrations in the Samples Containing Initial-
      ly One of the Five FWAs (100 mg/1).   The Tests Lasted 10 Days.      73

 18   BOD and Final FWA Content in the Samples Containing
        ca. 2 g/1 of the Activated Sludge  and the Addition
        of One of the FWAs  .	     74

 19   The Velocity v of the FWAs Decomposition in River and
        Distilled Water Exposed to Light  	     77

 20   The Adsorption of FWAs on Activated  Sludge	     79

 21   The Treatability of FWA-1	     81

 22   The Treatability of FWA-2	     81

 23   The Treatability of FWA-3	     82

 24   The Treatability of FWA-4	     82

 25   The Treatability of FWA-5	     82

 26   The Chlorophyll "a" Content  in the Culture of Chlorella
        After 7 Days of Exposure to the Presence of MEK	     85

 27   The Mortality of Lebistes reticulatus to DMA	     85

 28   Chlorophyll "a" Content in the Culture of Chlorella
        After 7 Days of Exposure to DMA	     86

 29   The Chlorophyll "a" Content in the Culture of Chlorella
        After 7 Days of Exposure to the Presence of DMF	     87
                                     Xlll

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                                  SYMBOLS


a       - Henry's coefficient of the equilibrium between volatile substance
          content in the liquid and gaseous phase
a and b - Langmuir's isotherm coefficients
c       - concentration of tested compound, mg/1
cg -    - tested substance effluent concentration, mg/1

CQ      - initial concentration or the inflow concentration, mg/1

kn      ~ kinetic coefficient of the nutrient medium biodegradation, decimal
ks      - kinetic coefficient of the tested compound biodegradation, decimal
          day'1
Kad     - the coefficient of the FWAs removal by the adsorption and removal
          with excess sludge g~« l-h"^-
Kb      - the coefficient of the FWAs removal due to the biodegradation
          g-h-h-1
KCOD    - overall treatability coefficient, being the COD decrease in the
          activated sludge unit per 1 mg/1 COD in the effluent per 1 g/1 MLSS
          and per 1 hour of retention time, g^l-h"1
Kph     ~ the coefficient of the FWAs removal by photolytic decomposition,
          g-.-4-h-1
Ks      - the tested substance removal coefficient, being the decrease of the
          tested substance contents in the activated sludge unit per 1 mg/1
          in the effluent per 1 g/1 MLSS and per 1 hour of retention time
          g-^l-h-1
L       - the BOD, remaining at the time t, mg/1 02
LC      - the final carbonaceous BOD, mg/1 02
Lu      - the unit oxygen demand,  caused by I mg of the given substance,
          mg 02/mg substance
m       - MLSS, dry mass, g/1
N       - NH3 content at the time  t, mg/1 NH3-N
N£    '  - final NH3 contents, mg/1 NH3-N
NOD     - the oxygen demand caused by nitrification, mg 02/1
R       - inhibition effect (the ratio of treatability coefficient in the
          test unit K,™  and control unit K    )

    ks  - The relative rate of the tested substance biodegradation (in the
r = —    monomolecular reaction phase), dimensionless
    K
     n
tQ      - lag phase of the tested  substance biodegradation in river water
                                    xiv

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t       - time needed by activated sludge to restore  normal  treatment  of
 1        wastewaters background in the presence of the  tested substance
t?      - time needed by activated sludge to decompose the tested  substance
Atj     - inhibition time of nutrient medium BOD in the  presence of the
          tested substance, days
At2     - inhibition time of the tested substance BOD, days
v       - the biodegradation rate in river water in the  phase of constant
          rate, mg/l-h
y       - BOD at the time t, mg/1 02
t       - the retention time, hours
Q       - the sludge age, days
                                      xv

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                              ACKNOWLEDGMENTS
     We would like to thank Project Officer Dr. Robert L. Bunch from
Municipal Environmental Research Laboratory, Cincinnati, Ohio for his
great help during the course of this project, for his comments and
suggestions to the methodology of work and evaluation of data.

     Our thanks to Dr. Joseph F. Malina from the University of Texas,
Austin and Dr. Robert D. Swisher for their help as consultants of
the project.

     Technical contributions to these studies were made by technical
staff of the Department of Water Chemistry and Biology of the Institute
of Meteorology and Water Management.  Their assistance is sincerely
appreciated.
                                   xvi

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                                  SECTION 1

                                INTRODUCTION
     The development of elaborate industrial societies in the United States
and in Europe, has  led to proliferation of a vast number of complex chem-
icals for industrial, agricultural and domestic use.  Some portion of these
compounds eventually find their way into municipal and industrial wastewaters.
Unless specifically removed by waste treatment processes, they ultimately
appear in receiving waters and water supplies, thus no longer is it suffi-
cient to remove biochemical oxygen demand to protect the oxygen resource of
the receiving water but individual organic compounds become a concern.

     Along with the benefits of chemicals there are risks.  Unfortunately,
exposure to some chemicals, sometimes in very small amounts, can lead to
tragic and irreversible biological effects including cancer (carcinogenesis),
transmissible genetic damage (mutagenesis), and birth defects (teratogenesis).
The negative effects of toxic organic substances are greater when the sub-
stances are resistant to biodegradability.  New organic compounds introduced
into the water environment should be biodegradable, easily removed in treat-
ment and their residual easily degraded in water bodies.  Knowledge of the
toxicity and biodegradability of organic compounds will aid in designing
wastewater treatment processes.

     This report describes the testing of twelve compounds both for bio-
degradability and toxicity.  The compounds tested were:  methylethyl ketone
(MEK), dimethyl amine (DMA), dimethyl foramide (DMF), p-nitrophenol (PNP),
o-chlorophenol (OCP), trichlorophenol (TCP), 2,2'-dichlorodiethyl ether
(DCDEE) and five flourescent whitening agents (FWA) used as components of
household detergents.

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                                 SECTION 2

                                CONCLUSIONS
     Biodegradation and toxicity of twelve organic compounds were studied.
The biodegradation tests performed were respirometric measurements, river
model, and activated sludge model.  Additionally, for some compounds supple-
mentary tests were made for evaluation of their volatility, photolysis and
adsorption on activated sludge.  The toxicity was measured with use of fish
Lebistes reticulatus and crustacean Daphnia magna.

     The obtained data permitted the calculation of several parameters char-
acterizing the properties of tested compounds.  From the respirometric data,
the unit oxygen uptake LU caused by 1 mg of a given substance, was calculated.
The processing of BOD curves parameters gave three kinetic characteristics:
the time A t  of the inhibition of the standard medium decomposition (yeast
extract or glucose), the time A t  of the inhibition of the tested substance
decomposition, and the ratio r = Rs/kn of the Streeter-Phelps coefficients
corresponding with the tested substance decomposition ks  and standard
medium decomposition kR.  This parameter indicates, whether the tested
substance biodegradation is faster r > 1 or slower r < 1 than the bio-
degradation of the standard medium.

     The river model tests indicate the lag phase duration to, which is the
time of acclimatization of river water biocenosis.  The same data permitted
the calculation of the rate of the tested substance decomposition v, mg/l-h,
during the phase of the constant rate of the decomposition.

     The tests with the activated sludge supplied data on the acclimatization
time ti, after which the activated sludge normally decomposes the wastewaters
background, and ^2, after which also the tested substance is decomposed.
The treatability of wastewaters containing the tested substance was char-
acterized by means of K coefficients, one referring to the tested substance
removal KS and the second one referring to the overall treatment KCQD meas-
ured as COD decrease.  Both coefficients are the decrease of tested substance
or of the COD, calculated per 1 mg/1 in the effluent, and per 1 g/1 MLSS
and per 1 hour of retention time.  The inhibiting effect of the tested
substance on the overall treatment of wastewaters was characterized by the
ratio R of KCQD values observed in the test unit and in the control unit.

     The results of the tests are summarized in Tables 1-5.

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                             TABLE 1.  THE RESPIROMETRIC DATA
Substance
MEK

DMA

DMF

PNP

OCP


TCP

DCDEE

FWAsx
Concentration Measured unit
test range oxygen demand, Lu
mg/1 mg C>2/mg subst.
50 - 800 2.12

40 - 900 2.13

80 - 440 1.40

10 - 100 1.30

5 - 1200 0


10 - 540 0.9

0.7 - 500 0

100 0
Kinetic parameters at
concentration CQ
co
mg/1
50
800
300
450
80
440
50
100
10
200
1200
12
90
0.7
500
100
At!
days
0.5
1.0
0
0
0
0
0
4
0
0.5
> 11
0
0
0
0
0
At 2
days
0.5
1.0
5
> 13
3
4.5
0.8
> 15
2
> 11
> 11
5
> 18
7
> 16

the
r
1
0.2
0.75
0
0.8
0.8
1.5
0
0.3
0
0
n.dxx
0
0
0

x The tests with all  FWAs gave the same results.
  not possible on the basis  of respirometric data
  demand, despite the partial  FWAs decomposition.
                                                   The  determinations  of At2  and r were
                                                   because  of the  lack of the oxygen
xx not determined.

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          TABLE 2.  THE DECOMPOSITION OF SUBSTANCES IN THE RIVER WATER
Substance


MEK
DMA
DMF
PNP

OCP

TCP

DCDEE

FWAsx
Concentration

mg/1
20
22
28
5
20
2
20
5
15
3
7
10
Kinetic parameters,
biocenosis not acclimatized
to
days
0.8
1.3
2
0
1.4
13
22
6.5
5
> 18
> 18
> 30
V
mg/l-h
0.6
0.4
0.55
0.1
0.35
0.02
0.10
0.13
0.27
0
0
0
Kinetic parameters, biocenosis
previously acclimatized
t0
days
0
0.8
0
0
0
0
0
0
2
_

-
V
mg/l-h
1.2
0.55
0.8
~ 0.3
~ 0.5
0.03
0.10
0.20
0.38


-
In the absence of the light.

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             TABLE 3.  PHOTOLYTIC FWAs DECOMPOSITION IN WATER
                       (LIGHT INTENSITY 1000 LUX)	
    Substance
Concentration
    mg/1
Rate of photolysis
  in river water,
      mg/l-h
Rate of photolysis
in distilled water,
      mg/l'h
FWA-1

FWA-2

FWA-3

FWA-4

FWA-5

10
50
10
50
10
50
10
50
10
50
5
6
9
13
1.5
5
2
4
5
7
7
11
14
13
5
5
8
9
11
12
     TABLE  4.   TREATABILITY  OF  THE  TESTED  SUBSTANCE  BY ACTIVATED  SLUDGE
          Substance
                        mg/1
                days    days    g'-'-l'h-l
MEK

DMA

DMF
PNP

OCP

TCP

DCDEE

FWA-1

FWA-2

FWA-3

FWA-4

FWA-5

200
400
20
135
70
5
200
5
200
5
25
5
10
10
40
6
200
5
80
4
44
4
40
0
0
0
14
38
0
0
0
-
0
-
0
0
0
0
0
0
0
0
0
0
0
0
8
9
6
12
38
~ 15
3*
6
-
0
-
_
-
0
0
_
-
0
0
-
-
_
-
high
high
high
high
high
high
0.7
0.2
0
high
0
0
0
2.1
2.5
0
0
0.03
0.01
0
0
0
0
1
1
1
~ 0.7
~ 1
~ 1
1
1
0
1
0
1
1
1
~ 1
~ 1
0.7
~ 1
0.3
~ 1
1
1
~ 1
xthe value is the additional time needed by the sludge previously acclimatized
 to the presence of 40 mg/1 PNP.
                                      5

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          TABLE  5.   LETHAL  CONCENTRATIONS  OF  THE TESTED  SUBSTANCES  TO
                    Lebistes  reticulatus AND  Daphnia magna

                               LC50-  96 h  to         LC50-  24 h to
              Substance     Lebistes  reticulatus     Daphnia magna

MEK
DMA
DMF
PNP
OCP
TCP
DCDEE
FWA-1
FWA-2
FWA-3
mg/1
5700XX
60XX
1300XX
19
12
4.5
190
16
1800
110
mg/1
n.tx
ti
!!
tl
1!
1!
1!
22
3900
surpasses
                                                     solubility

              FWA-4               3000                  9400

              FWA-5	6400	5600

             x not tested
            xx LC5o- 24 h


     The obtained data lead to the following conclusions:

     MEK is easily biodegradable.  The respirometric data show that MEK
practically does not inhibit the microbiological activity and is biodegraded
at its initial concentration up to 800 mg/1.  At the high concentrations,
the biodegradation rate is lower.  The river model tests and treatability
tests confirm that MEK is easily biodegraded and does not affect the overall
treatability.   The toxicity of MEK is low, its LC50 for fish Lebistes is
near 6 g/1.  This is much more than the value, which could be expected in the
wastewaters.

     DMA, is easily biodegradable at the concentrations not surpassing
300 mg/1.  The biodegradation rate is rather high, and the time needed for
microbiological acclimatization is short.  In the treatment by activated
sludge, DMA is easily removed from wastewaters and has little effect on the

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overall treatability of wastewaters.   The toxicity of DMA is high.   A con-
centration of 60 mg/1 of DMA causes 50 percent mortality of fish.

     DMF is easily biodegraded.   Its unit oxygen demand and unit amount of
NH3 involved in the biodegradation are not very high.   The DMF biodegradation
in the rivers and its removal by means of activated sludge needs a period
for microorganisms acclimatization.  The rate of DMF removal by acclimatized
sludge is high, and no harmful affect of DMF on the overall treatability
occurred.  The toxicity of DMF is low.  The value of LC50- h f°r fisn is
above 1 g/1.

     PNP is biodegradable at concentrations up to 50 mg/1.  At the higher
concentrations, 100 mg/1 and above, PNP is toxic and biodegradation does not
occur.  In the river water at concentrations up to 20 mg/1, PNP is bio-
degraded at a rather high rate.   The activated sludge removes PNP from
wastewaters with high efficiency.  Also the overall efficiency of wastewater
treatments is not affected by the PNP presence.  PNP is highly toxic to
higher animals; its LCso- 96 h is ca. 20 mg/1.

     OCP is biodegradable only at low concentrations up to 10 mg/1.  At
concentrations up to 200 mg/1 OCP is not biodegraded, but it does not inhibit
significantly the other biochemical processes.  OCP concentration of 1200
mg/1 causes the poisoning of the microorganisms.  OCP biodegradation in the
river water needs a long period of acclimatization, lasting 2 to 3 weeks.
Even after this period, the biodegradation rate is low.  The activated
sludge removes OCP with low efficiency.  The overall treatability is not
affected by 50 mg/1 OCP, but 100 mg/1 OCP causes the poisoning of the
activated sludge.  The toxicity of OCP to fish is high, LC50- 96 h being
equal to 12 mg/1.

     TCP is biodegradable at concentrations up to 35 mg/1, but needs a
certaln~period for microorganisms  acclimatization.  The TCP biodegradation
in river water proceeds at a rather high rate.  The activated sludge
removes TCP from wastewaters containing up to  18 mg/1.  This TCP content
does not affect the overall efficiency of the  wastewater  treatment, but
25 mg/1  causes poisoning of the  sludge, and both TCP and  COD removal
drop  down to  zero.  TCP is very  toxic to higher animals.   Its LCsg- 96 h
to fish  amounts to ca. 5 mg/1.

      DCDEE  is  a biologically inert substance.  No DCDEE biodegradation
was observed,  even at a low concentration of  0.7 mg/1.  DCDEE does not
affect the microbiological activity,  even at  concentrations as high as
500 mg/1.  The only effect observed was the inhibition of the nitrification
partially occurring at 3 mg/1 DCDEE.  The river model and results  obtained
with  use of the activated sludge model confirm these conclusions.  DCDEE is
a volatile  substance  and may be  partially blown off the wastewater in  the
aeration chamber.  The LC50- 96  h  for fish  is  190 mg/1.

      FWAs do  not  cause any oxygen  demand but  they  are partially decomposed
at thT^nditions  of  the respirometric tests.   All  FWAs  are quite  resistant
in the river  water in the absence  of light.   Illumination of  the  FWAs
solutions  causes  their decomposition at  a high rate.   Both in the

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respirometric and the river water tests,  the FWAs decomposition consist most
probably in transfiguration of the molecules or in their breaking into large
fragments.

     In the treatment by the activated sludge,  FWAs were resistant,  except
FWA-1 which was biodegraded.  FWA-3 was partially removed,  but at a  very
low rate.   FWAs do no affect the overall  treatability of wastewater  until
their contents surpass 80 mg/1.   The results of the bioassays show that
FWA-1 is the most toxic, the toxicity of FWA-3  is moderate  and the toxic-
ities of other FWAs are low.

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                                  SECTION 3

                               RECOMMENDATIONS


     The biodegradation study of organic compounds in the respirometer,  in
the river water model and in the activated sludge model gives useful infor-
mation on the condition of organic compounds removal in the treatment plant
and on their fate in river water.  Those data supplemented by the toxicity
data can be useful in elaborating the criteria for the safe concentration
of organics in the discharged wastewater and the receiving water.

     Based on the obtained results of the study, the general recommendations
formulated are:

     MEK is a substance of weak toxicity and is easily biodegraded, there-
fore Its" harmfulness to the environment is limited.  However, the BOD of MEK
solutions is high and may cause oxygen deficiency in the rivers polluted with
MEK or extensive BOD5 load in the wastewater.  MEK does not contain hetero-
atoms in the molecules, therefore the biodegradation of the high MEK contents
will require the addition of mineral nutrients.

     DMA is moderately toxic and easily biodegraded.  The high BOD and the
ammoniT~development  in the DMA biodegradation process may cause, in .rivers
polluted with DMA, an oxygen deficiency and an  increase in ammonia.

     DMF is weakly toxic and easily biodegraded by acclimatized microorganisms,
The treatment of wastewater, containing DMF, by means of the  activated sludge
needs the acclimatization of the sludge to the presence of DMF.

     PNP is  a highly toxic  substance.  PNP biodegradation occurs in  river
water~atf low concentrations.  The wastewater  containing PNP  can  be  treated
by activated sludge  after sludge acclimatization.

     OCP is  a highly toxic  substance.  OCP  is biodegraded at  low concentra-
tionsTrf the river water and  in the  activated sludge process, but  at a  low
rate.   Long  retention  times might be  needed.

     TCP is  the most toxic  of  all  substances  tested.   The TCP biodegradation
proceeds" at  low concentrations.   It  is  suggested that severe limitation  be
placed  on  TCP  discharge  into  sewage  systems  and into rivers.

     DCDEE  is  moderately toxic,  but  is  a biologically resistant  substance.
 Its presence in the  wastewater does  not  affect  treatability,  but DCDEE  is not
removed except by the  partial  blowing off with  the air in  the aeration  basin.
 Special treatment may  be needed.

-------
     FWAs are weakly toxic except highly toxic FWA-1 and moderately toxic
FWA-3.  In the treatment process FWAs are resistant, except FWA-1 which is
removed at a high rate and FWA-3 which is removed slowly.  In the natural
environment, FWAs are easily decomposed due to photolysis but this process
has not led to FWAs complete decomposition.  Rather, photolysis causes FWAs
molecules to break into large fragments.

     Not enough compounds were examined to form any conclusions as to any
relationship between chemical structure and biodegradability.  It is recom-
mended that such be done.  It will not be possible to test all the organic
compounds now found in wastewater and all the new ones that will be developed
in the future.   Some chemical, physical or structural property or a combin-
ation of several parameters must be found that would lead to the prediction
of the behavior of organic compounds in wastewater treatment plants and
surface waters.
                                     10

-------
                                  SECTION 4

                           BACKGROUND INFORMATION


     Methylethyl ketone CH3.CO.C2H5 is a liquid boiling at 81 °C; one liter of
water dissolves 292 g of MEK at 20 °C.  MEK is used in industry as a solvent.
MEK is found in some industrial wastes (e.g., in the waste from production
of synthetic leather Corfam, paints and lacquers).

     MEK in concentrations up to 50 mg/1 does not influence the biochemical
processes (67).

     According to Turnbull  (61), the TLm for fish Lepomis macrochirus is
5640 mg/1 and a noticeable  influence on these fish was found at 3380 mg/1.
TLm for fish Gambusia affinis was found to be 5600 mg/1 (64).  Bringmann and
Meinck (9) determined the toxic concentration of MEK for bacteria Pseudo-
monas as 2.5 g/1, for algae Scenedesmus as 12.5 g/1, and for protozoa
Colpoda as 5 g/1.  The experiments performed by Wjodek (70) have shown that
LC50- 48 h for Asellus aquaticus is 2850 mg/1.  WXodek proposes that the
permissible, safe concentration is 28.5 mg/1.

     The following methods  of MEK determination are known:

- Gas chromatographic method (after distillation with butyl  alcohol).  The
  limit of detection is equal to 0.004 mg/1  (12).

- Spectrophotometric method based on  the reaction of MEK with vanillaldehyde.
  The developed color is measured at  600 nm  (62).

- Redox titration with the  iodine in  alkali  solution  (59).

- Amperometric titration with hydroxylamine  hydrochloride  in a waterless
  solution of pyridine and  isopropyl  alcohol  (7).

     Dimethyl amine CH5.NH.C%  is a gas  condensing  at  7  °C.  DMA  is  easily
dissolved  in water, forming an  alkali solution.  DMA  is found  in  some
industrial waste  (e.g., from the production  of  synthetic  leather  Corfam).   It
is used in the  synthesis of many substances.

     The  toxic  influence of DMA on higher  organized life  is  more  marked  than
on lower  organisms.  Toxic  concentration for fish  Leuciscus  cephalus is  30  -
50 mg/1  (19) whereas for algae  Scenedesmus and  for  protozoa  Colpoda  it  is
250 mg/1.  A  toxic  influence was found for bacteria Pseudomonas  at  the
concentration  1  g/1  (38) .   Corti  (13)  observed  that DMA  in concentration
of 205 mg/1 influences  fish Salmo  irideus  after 33  -  40  sec  and  death

                                       11

-------
 occurred after 10 -  13  min.   Water Quality Criteria (66)  states  0.7 mg/1  DMA
 changes  the taste of the fish meat of trout.   Dzhanashvili  (15)  proposed  the
 value of permissible concentration of DMA as  0.1  mg/1.

      DMA is determined  usually by  GC  method (17),  (30),  (41).  Kubelka (30)
 set  the  detection limit of DMA in  water  as 0.01 mg/1.   Other methods of DMA
 determination  in water  are as follows:

 -  Spectrophotometric method with carbon  disulfide and ammonia  solution of
   cupric acetate (10),  (52).

 -  Fluorometric method by the exciting with light  of 365 nm  and by  the
   measurement  of the emitted fluorescent light at  535 nm  (650 .   The samples
   are prepared by use of the thin  layer  chromatography.

 -  Polarographic method  (1).

      Dimethyl  formamide  (CH3)2N.CHO  is  a liquid  boiling  at 150  °C.   DMF  is
 soluble  in  water in  any ratio.  DMF is used in chemical industry as solvent.
 It occurs in wastewater from the production of synthetic  leather Corfam.

      According to Zamyslova  and Smirnova (74)  DMF  in concentration  10 - 500
 mg/1  does not  change the BOD of water  and wastes.   High amounts  of  DMF  in
 water causes an increase of  ammonia.   Permissible  concentration  of  DMF  in
 receiving water in the  Soviet Union is 10 mg/1.

      The bioassays of DMF  with Asellus aquaticus  (73) indicated  that  LCcn-
 48 h  is  equal  to  9628 mg/1.

      DMF contents  in water is usually determined by the gas chromatographic
 method (30), (34).

      The Spectrophotometric method is based on the reaction of DMF  with
 picric acid forming  a yellow  colored complex  (11).

     p-Nitrophenol is a  solid compound, melting at  114 °C and boiling at
 279 °C, sublimating  at a temperature below b.p.  Depending on pH, PNP may
 exist in two tautomeric  forms:  the benzene or quinone form:
                        pH
             2
high pH
                                               0 = N - OH
       benzene form                         quinone form

PNP is used for wood impregnation.  It is used also as raw material in
production of pesticides and azo dyes.

     Biodegradation of PNP was studied by Fitter (47), (48).   Comparative
investigation of various nitro phenols showed that biodegradation decreases

                                      12

-------
with the increase of nitro groups on the molecule.  The highest rate of
biodegradation was shown by the nitrophenols with the nitro group in the
para position.  Fitter  (48) measured the rate of PNP biodegradation with
use of COD determination and found it equal to 17.5 mg COD/g-h.

     The following methods of PNP determination are known:

- Spectrophotometric method based on reduction of nitro groups to amine
  groups and ,by diazotization, the dye is developed and measured (44).

- Spectrophotometric method based on development of yellow colored sodium
  pseudosalt of nitrophenol in presence of sodium hydroxide (4), (45), (56).

- Polarographic measurements in the presence of methanol and sodium hydroxide
  made at Ej/2 =0.98 - 1.05 V (73).

- Gas chromatographic method (8), (26), (55).

- Thin layer chromatographic method (40), (42), (58).

- Phosphorescence method (37).

- Atomic absorption spectrophotometry (AAS) method based on the creation of
  a complex compound of PNP with cobalt and determination of cobalt by AAS
  method (39).
     o-Chlorophenol is a liquid melting at 9 °C and boiling at 175 °C.  The
                    solubility in water at 20 °C is equal to 28 g/1.  OCP has
                    very strong antiseptic properties.  It is used in produc-
                    tion of antiseptic agents and pesticides.  Additionally
                    OCP can be developed in water during the chlorination
                    process.

     Ingols (22), (23), (24) performed an extensive study on the degradation
of chlorophenols by means of activated sludge.   He found that the persistence
of chlorophenols increases with the increase of the number of chlorine atoms
on the molecule and depends on the isomeric position of those atoms in the
aromatic ring.  It was found that OCP in concentration 100 mg/1 was fully
degraded within 3 days.  Fitter (47), (48) found the rate of OCP biodegrada-
tion by activated sludge, determined on the basis of COD measurement, was
equal to 25 mg COD per hour and per 1 g of activated sludge.

     Lammering and Burbank (31) found that the introduction of chlorine into
phenol ring increases the toxicity.  The toxicity of chlorophenols increases
with the increase of the number of chlorine atoms in the phenol ring (13),  (63),
(66).  Ingols (22),  (23) found that TLm at 23 °C for fish is equal to 58 mg/1.

     OCP content can be determined by the following methods:

- Spectrophotometric method based on the formation of the indophenol dyes
  in the reaction of phenols with 4-aminoantipyrine (21), (53), (56).  It is
  the method used most commonly for determination of phenols.


                                      13

-------
- Spectrophotometric method based on reaction of chlorophenols with diazo-
  tizated p_-nitroamine and magnesium ions (72) ,  (32) .

- Titrimetric method based on bromination or chlorination of aromatic ring
  and iodometric titration of the excess oxidation agents (3) , (29) ,  (49) .

- Gas chromatographic method (2), (27),  (46).

     Tr i ch 1 oropheno 1 is a solid compound, melting at  67 °C and boiling at
244 °C and soluble in water in the amount of 0.8 g/1  at 20 °C.  The use of
TCP and occurrence in wastes and water is similar to  OCP.

     Biodegradation of TCP was studied by Ingols (23) .   In the tests lasting
two days TCP was totally degraded at a concentration  of 50 mg/1, but at a
concentration of 400 mg/1 TCP, the biodegradation was  completely inhibited.
According to Ingols (23) the TLm at 25 °C for fish is  equal to 3.2 mg/1.

     TCP can be determined by the following methods:

- Spectrophotometric method based on the formation of indophenol dyes in
  reaction of phenols with 4-aminoantipyrine (2) , (53) , (69) .

- Thin layer chromatographic method (68), (75).

- Gas chromatography (20), (43), (51), (50).
     2,2'-dichlorodiethyl ether a^Cl.O^O.Ct^.O^Cl is a colorless liquid
boiling at 178 DC.   The solubility in water is 1 g/1 at 20 °C.   DCDEE is used
as an insecticide,  as cleaning agents and as a solvent.  It is  a byproduct
in the production of the synthetic fibers, glycoles, antifreezing agents and
some pesticides (36) .  Meager data exist on toxicity of DCDEE (60) .
     DCDEE is determined in water mostly by gas chromatography (14),
and gas chromatography-mass spectrometry method (6).
(28)
     Fluorescent whitening agents are used for the improvement of the color
of the textiles, paper, plastics and other materials.   They are added to
detergents used in households.  FWAs are solid compounds, soluble in water
in the range 0.5 - 100 g/1 depending on the kind of FWA.   In the frame of
the present work five commercial FWAs were studied.  The samples contained
8 - 30% of the sodium chloride.

     The structural formulas of five tested FWAs are given below:
               H
                                   FWA-l
                                                    H2f  ^H2
                                                    H2C   CH2
                                      14

-------
 I
Ul
 I
-p-




* f-
2-rt
X
u>
o
o
\
O/ Wo''
x
ro
O
M ,
1
2-X
I
^^V
                                                                                                                                                              IV)

-------
Jensen (25) found that FWA can accumulate in fish.  He analysed various
species of fish taken from rivers in Sweden and found measurable quantitites
of FWA in the muscle of fish.  When fish were returned to water not con-
taining any whitener, they lost the FWAs very quickly (57).

     The study of toxicity of FWAs for trout showed that LCcn- 96 h ranged
from 108 - 1780 mg/1 (76).

     The most common method for determination of the FWA in water is
fluorimetric method (16), (18), (33).  The mercury lamp is used for
excitation with the wavelength of 370 nm, and the fluorescence is meas-
ured at 440 - 480 nm.  Thin layer chromatography method is used also for
determination of FWA.

     There are some advantages to the combination of the two above mentioned
methods, i.e. the separation of the FWA by use of thin layer chromatography
and the identification by means of fluorimetric measurement (18).  The
combined technique of TLC with radiometric measurement and with IR-spectro-
photometry is also known  (54).
                                       16

-------
                                  SECTION 5

                           EXPERIMENTAL PROCEDURES

RESPIROMETRIC MEASUREMENTS

Apparatus

     The BOD tests were carried out by means of "Sapromat" respirometer.
The principle of measurement is the following:  The sample of solution,
in which the BOD is to be measured, is put into the 0.5 1 flask in the
amount of 332 ml.  The flask is then hermetically sealed.  The oxygen uptake
in the solution causes a reduction of the pressure in the air space in the
flask which switches on the electrolytic oxygen generator.

     The automatic counter records the amount of the produced oxygen, which
is equal to the amount of oxygen taken up by the test solution.  This is
printed every hour on a paper tape.

     In the air space of the flask, a basket is filled with soda lime to
absorb C02 produced in the biochemical process.

     One apparatus is equipped with 6 or 12 independently operating flasks
and printers.  All these flasks are kept in the same room at 20 ±1° C. Mag-
netic stirrers, individual to each flask, allow the equilibrium between
oxygen contents in the liquid and gaseous phase to be reached in a short
time.

Materials

     The dilution water was prepared with tap water, previously aerated by
air during 24 h, and with addition of the following mineral salts:  8.5 mg/1
KH2P04, 21.75 mg/1 K2HP04, 33.4 mg/1 Na2HP04 - 7H20, 1.7 mg/1 NH4C1, 22.5
mg/1 MgS04 •  7H20, 27.5 mg/1 CaCl2, 0.25 mg/1 FeCl3 •  6H20.

     The nutrient medium was prepared by dilution of 200 mg yeast extract
or glucose in 1 liter of the dilution water.  The tested solutions were
prepared by adding the determined volumes of the tested substances stock
solutions into the dilution water.

     As inoculum the following seeds were used:

     - the municipal wastewater, obtained from the Warsaw sewerage and
aerated for 24 hours before use

     - the supernatant sample from the laboratory activated sludge
installation
                                    17

-------
     - the activated sludge from the same installation.

     In the tests of activated sludge respiration in the presence of FWAs,
the test solutions were prepared with settled activated  sludge,  to which the
FWAs solutions in the dilution water were added.

Measurements

     In every case, the BOD was automatically recorded every hour during the
test lasting usually 1 to 3 weeks.   Additionally, chemical analyses were
carried out at the beginning and at the end of the tests on the  concen-
tration of the tested substance and, in some cases, the  NHv, NO? and NO?
content.  In some tests the concentration of the  tested  substance was
determined every day.  A flask from six flasks containing the same solu-
tion was withdrawn daily from the apparatus and its contents analyzed.

RIVER MODEL

Apparatus

     The experiments were carried out in 10-liter bottles, filled with the
river water and the known amounts of tested substances.   The water in the
bottles was stirred mechanically at a rate causing the aeration  conditions
similar to the aeration in the rivers.  The water in the bottles was
exposed to the light of the fluorescent tubes (at the intensity  of approx-
imately 1000 lux).  The tests were performed in all day  illumination or in
regulated illumination (12 h with light and 12 h  in darkness).

Materials

     The river water was obtained from the Vistula river upstream of
Warsaw, and next it was seasoned during at least  2 weeks in the  100 liter
polyethylene barrel.  During this seasoning the water was aerated by
bubbling the air.  The test solutions were prepared by adding the tested
substances stock solutions into this river water.

Measurements

     From the river models, the samples were withdrawn periodically and
analysed.  The tested substance concentration and in the certain tests
also NHg, N02 and NO^ content were determined.  The frequence of sampling
and analyzing depended on the speed of biodegradation of any tested sub-
stance, usually it was made every day.
TREATABILITY TESTS

Apparatus

     The test of the treatability of wastewater containing tested sub-
stances was carried out by means of a laboratory activated sludge unit,
presented schematically in Fig. 1.

                                     18

-------
Figure 1.  Laboratory activated sludge unit.
     This unit consisted of a storage tank 1 (30 liter volume),  containing
the wastewaters  with tested substance, the peristaltic pump 2 feeding the
aeration chamber 3 with wastewater.  The aeration chamber was separated
by the wall from the settler 4.  The volume of aeration chamber was equal to
1 liter, the volume of settler 0.5 liter.  The mixed liquor in the chamber
was aerated by means of the air pump 5.

     The parameters of operation were:

     - retention time: tr= 1 to 6 hours.
     - sludge age:

     - MLSS:
0=5 days.

m = 3 to 4 g/1 (dry mass).
Materials
     The activated sludge was obtained from the municipal treatment plant
and acclimatized during 2 weeks in the storage unit, similar to the unit
presented above, but larger  (volume of aeration chamber equal 8 liter).

     The wastewaters were simulated by preparing a solution of 0.6 g/1 meat
extract, 0.12 g/1 NH4C1, 0.1 g/1 MgS04 • 7H20, 0.033 g/1 NaHC03 in the tap
water.  BODr of these wastewaters was equal to ca. 360 mg/1 02; COD was ca.
420 mg/1 02.  These wastewaters were used to feed the activated sludge
units.  Usually 4 units were in operation simultaneously.  The test units
were fed with the wastewaters, with addition of the tested substance at
known concentration.  The control unit, operating simultaneously was fed
with wastewaters without any addition of test substances.

Measurements

     The following analyses were carried out:

     - the determinations of tested substance concentration in the waste-
waters flowing into the test units and in the effluent,
                                     19

-------
     - the determination of COD in the inflow and in the effluent,

     - the MLSS (dry mass).

     Additionally, the technological parameters were controlled.  The
retention time was controlled by means of the effluent volume measurements
and the DO concentration was maintained at 2 mg/1 or higher.

TOXICITY TESTS

     Two kinds of bioassays were carried out.  The first was the deter-
mination of the lethal concentrations of tested substances, i.e. the
concentrations causing the death of 50 percent organisms used in the test
during 24 or 96 hours.

               LC5Q- 24 h or LC50- 96 h.

     The following organisms were used in the bioassays:  the fish was
Lebistes reticulatus and the crustacean was Daphnia magna.

     In the second type of bioassay, the influence of tested substances
on the changes of the chlorophyll content in the cells of algae Chlorella
was analyzed.

Tests with Lebistes reticulatus

     The tests were carried out following the procedure described in
Standard Methods (53).

     In every test, 10 test organisms were put into the 400 ml solution
of tested substance in the open vessel.  The organisms dead after 24, 48,
72 and 96 hours were counted and removed to avoid the pollution of test
solutions.   In this kind of test, the concentration of tested substance
may decrease slightly during the test.

Tests with Daphnia magna

     In every test 10 organisms were put into the 200 ml solution of
tested substance in an open vessel. The organisms dead after 24 hours
were counted.

Tests with algae

     The procedure of tests  was based on a method recommended by EPA (5).
The tests with use of algae  Chlorella consisted in the measurement of
the chlorophyll "a" content  changes after 7 days of exposure to the
presence of the tested substance.  The tests were carried out in the
300 ml conical flask, containing tested substances in 100 ml nutrient
solution, inoculated with 20 ml supernatant of algae culture.  The
culture of algae was kept at 18 °C ±1 °C and illuminated with the
fluorescent tubes.
                                    20

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Materials

     All test solutions were prepared with use of activated carbon treated
tap water, pH equal 7.6 to 8, the calcium content 80 mg/1 and magnesium
content 15 mg/1.  Before use, the water was aerated.

     The tested substances were always added to the test solutions, using
the same stock solutions as in the biodegradability tests.  The concen-
trations of tested substance in the test solutions represented always a
geometric series, e.g. 1.0, 1.8, 3.2, 5.6, and 10 mg/1.

Test organisms

     The fish Lebistes reticulatus were selected before the tests, so that
all individuals were the same age (just before they revealed the sexual
dimorphism).

     The population of the crustacean Daphnia magna used in the tests was
prepared in the following way.  The matured females of Daphnia were put into
the aquarium in the amount of 20 to 30 individuals.  After 1 to 2 days, the
new generation was hatched.  After the next 5 days, these young organisms
were used for the tests.

     The algae Chlorella sp. wild strain were raised with use of nutrient
solution pre'pared following the EPA standard (5).  The test solutions con-
tained the same nutrient.

SUPPLEMENTARY EXPERIMENTS

     The proper interpretation of the results of experiments needs some
information on the physico-chemical properties of tested substances.  If
this information was not available in the literature, additional experi-
ments were carried out to obtain the needed data.

     So, the following experiments were made:

     - the tests of volatility of MEK, DCDEE and OCP from the dilute
aqueous solutions

     - tests of photolytic decomposition of FWAs

     - tests of adsorption of FWAs on the floes of activated sludge.

     The tests of volatility were made by means of dry air bubbling through
the dilute solutions of tested substances and measurement of the loss of
the sample weight and the decrease of tested substance concentration in the
sample.  Henry's coefficient of equilibrium between the concentration of
tested substance in the liquid and the gaseous phase was calculated.

     The tests of photolysis consisted of the measurements of FWAs con-
centration changes in the solutions of FWAs in the distilled water,
                                    21

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 exposed to the light of fluorescent tube at the known intensity.   As pH has
 the influence on this process,  the solutions contained buffers,  so that pho-
 tolysis was tested in the pH range 4 - 9.   -

      The tests of FWAs adsorption were made by means of measurements of FWAs
 concentration decrease in the supernatant  after the contact with  activated
 sludge lasting 1 hour.  At the  same time,  the activated sludge dry mass was
 determined which permitted the  Langmuir isotherm coefficients to  be
 calculated.

 ANALYTICAL PROCEDURES

      COD was determined by use  of dichromate method with addition of HgS04
 and AgS04.   The samples were kept at the boiling temperature under the  reflux
 condenser during 2 hours and after cooling they were titrated with the
 solution of Mohr's salt in the  presence of 1,10-phenanthroline-ferrous
 sulfate complex.

      The Kjeldahl  nitrogen was  determined  by means  of digestion with cone.
 H2S04 without the  former distillation of NH3.   After digestion, the ammonia
 was distilled off  and determined  by means  of Nessler method.   The Kjeldahl
 nitrogen content was calculated by substraction of  NH3  content in the raw
 sample from the result of the determination.

      Nitrites determinations were made  by  spectrophotometric  method with
 sulfanilamide and  N-(l-naphtyl)-ethylenediamine.

      Nitrates were reduced to nitrites  by  means  of  amalgamated cadmium  and
 determined  as N02  by the method described  above.

      Mixed  liquor  suspended solids  MLSS (dry mass)  were  determined  by
 filtering a known  amount of mixed liquor through Whatman's  filter paper and
 drying at 105 °C until  constant weight.

 Special  procedures

      The tested substances  were determined by means  of procedures developed
 in  the frame of the  present  work.   Three methods were used:   GC,  spectro-
 photometric  and fluorometric  methods.   All GC determinations were made by use
 of  the chromatograph Pye Unicam 104,  equipped with  flame ionization       ""
 detector.   Spectrophotometric determinations were carried out by means
 of  Pye Unicam spectrophotometer SP  600  equipped with cells of  1 cm  light
 path.  Fluorometric  determinations were made by use of the fluorometer
 Aminco.

 Methylethyl  ketone,  MEK

     Gas  chromatographic method was used.  The column, 2.1 m long and 4 mm
 diameter, was  filled with Porapak Q  (polystyrene), coated with polyethylene
 glycol 1000  as  stationary phase.  The carrier gas (nitrogen) flow rate was
 30 ml/min.  The temperature of column was 83 °C. 'The aqueous samples of
MEK were injected in the amount  of 5 yl each.  The retention time  was

                                     22

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9 min 45 sec.  The area of the peaks was proportional to the MEK concentration
within the range 0.3 to 200 mg/1.

Dimethyl amine, DMA

     The GC method was used.  The column 2.7 m in length and 4 mm in diameter
was filled with Chromosorb T (PTFE), 30 - 60 mesh, with 20 percent addition of
Triton X - 100 and 2 percent addition of KOH.  Carrier gas (nitrogen) flow
rate was 60 ml/min.  The column temperature was 96 °C, the retention time
1 min 45 sec.  The samples of DMA were treated with KOH solution to keep
pH ca. 12 and were injected into the apparatus as aqueous solution in the
volume of 5 yl.  The detection limit was 1 mg/1 DMA.

Dimethyl formamide, DMF

     DMF was determined by means of hydrolysis with use cf cone. HC1 (1+1)
and heating the sample on the boiling water bath under reflux condenser for
1 hour.  After cooling, KOH was added to reach pH ca. 12 and next the DMA
involved was determined by GC method.

Para-nitrophenol, PNP

     The spectrophotometric method was applied.  The quinone form of PNP
forms with NaOH the yellow pseudo-salt intensively colored.  The absorbance
of the light at the wavelength 405 nm is proportional to the PNP content
within the range 0.2 to 10 mg/1.

Ortho-chlorophenol, OCP

     The spectrophotometric method was applied.  The samples were treated
with the 4-aminoantipyrine  and potassium ferricyanide.  The involved
indophenol dye was measured spectrophotometricly at  light wavelength 510 nm.
Direct determination was possible within a range of  OCP concentration from
 0.5 to  5 mg/1.  The substances contained in  the yeast extract,  mineral
nutrients and  in the river  water did not interfere with the determinations.

Trichlorophenol, TCP

     TCP was determined similarly  as OCP with 4-aminoantipyrine method.   The
 absorbance of  the  formed dye  was measured at the  wavelength  510 nm.  Direct
 determination  of TCP  in the tested  solutions is possible within a range
 of concentrations  0.5  to 5  mg/1.

 Dichlorodiethyl ether, DCDEE

      DCDEE was determined  by  means  of  GC method.   The column  2.1 m  long  and
 4 mm diameter  was  filled with Chromosorb T  40 -  60 mesh,  coated with
 Triton X -  100 as  stationary  phase,  added  in the  amount  of  5  percent per
 weight.   The flow of  the nitrogen  as the carrier  gas was  30  ml/min.  At  a
 column temperature of 118  °C  the retention  time was  6 min  10  sec.   The  aqueous
 solutions  of DCDEE were injected in a  volume of  10 yl.   The  detection  limit
 amounted to  0.2 mg/1  DCDEE.


                                      23

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Fluorescent Whitening Agents, FWAs

     The fluorometric method was applied.  In this method, a UV beam passes
through the cell with the tested solution and the light emitted by the
solution at the direction rectangular to the UV beam is measured at the
wavelength 450 nm.

     Turbid samples were previously cleared by means of centrifuging at
12000 rpm.  As the measured signal depends on pH, phosphate buffer was used
to keep pH at the constant level of 7.2.  The apparatus was standardized
with quinine sulfate solution.  The calibration curves were prepared
individually for each FWA.  The apparatus gave linear response within the
FWA concentration range 1 to 10 mg/1.  The solutions with higher FWAs content
were adequately diluted before measurement.
                                     24

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                                  SECTION  6

                           METHODS OF  CALCULATIONS

RESPIRCMETRIC DATA

Long Term BOD Curve Examination

     If the sample, which BOD is measured, contains  the  nutrient medium
(yeast extract or glucose and mineral  salts)  with addition of the  specific
organic compound, which biodegradability is  tested,  the  resulting  BOD  curve
has usually the shape schematically presented on the Fig.  2.
         BOD, mg/l 02
 Figure  2.   Typical  shape  of BOD curve of a solution containing nutrient
            medium and  a specific organic compound.
                                      25

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      The  process  of biochemical  oxygen uptake  can be  divided  into  the
 following subsequent phases:

      -  Phase  A, being  lag phase,  during which  oxygen  uptake is very small or
        none.   This  phase corresponds with the  period  of microorganisms accli-
        matization to the conditions of test.

      -  Phase  B, being  growth phase, during which the  microorganisms are
        multiplying, so that oxygen uptake is accelerated.  The curve is then
        concave.

      -  Phase  C, during which the  organic components of the nutrient medium
        are in increasing scarcity in comparison with  amount of bacteria, so
        that the process is restrained and the  BOD curve is convex.

      -  Phase  D, being  second growth phase, during which the population of
        bacteria,  able  to decompose the tested  substance is growing, so that
        oxygen uptake for tested substance decomposition is accelerated and
        the BOD curve is concave.

      -  Phase  E, analogous to phase C, during which the tested substance con-
        tents  is in  the increasing scarcity in  comparison with the amount of
        bacteria able to decompose this substance.  The BOD curve is then
        convex.

      -  Phase  F, during which the  BOD accelerates once more because of the
        oxygen  uptake for nitrification of ammonia present in the tested
        solution.

      -  Phase  G, during which the  BOD curve is  approximately straight line
       with little slope.   This phase corresponds with the period, during
       which  the nutrients and the tested substance are almost completely
       removed and BOD  is caused mostly by endogenous respiration of micro-
       organisms.

      In almost all experiments made in the frame of the present work,  the
following equation can be used to describe the BOD curve sections:

      - lag phase  (phase A),  lasting to the moment t :

                         y a 0,  0 < t <  t0,

where y is BOD at  the moment t

     - growth phase B,  lasting from the moment t  to t-, :
                    y = cn •  10n-0}  t0 < t
where cn and bn are constants, the last being the exponential growth coeffi-
cient corresponding with the decomposition of the nutrient medium components.
                                     26

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     - monomolecular reaction phase C, lasting from the moment
described by the classic Streeter-Phelps equation:
                                                                  to
where y, is the BOD at the moment t,,  LI is the residual BOD at the moment tl
and k^ is the kinetic coefficient of the decomposition of the nutrient medium
components.

     - the phases D and E are analogous to the phases B and C, but correspond
with the tested substance biodegradation:
               y =
               y =
                                                    3,
                        L[l -
where C  and b  are the constants, L3 is the residual BOD at the moment t3,
k  is tile kinetic coefficient of tested substance biodegradation.
 s
     Nitrification phase F proceeds usually in some irregular way and was not
described with any equation.  In the phase G (endogenous respiration), the
oxygen uptake rate is almost constant, equal Re:
                         y =
                                  Re(t-t5)
     The  expression  z =  log dy/dt transforms  any of  equations to  the  linear
 function  of  time  t.  Thus, the  graph  of  the dependence  of  z_ on  t  has  the
 shape schematically  presented on the  Fig.  3.
                                                               log Re
                                                         time, days
 Figure 3.   The typical  BOD curve transformed by equation z = log dy/dt,

                                      27

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     The BOD record made every hour enables one to calculate the BOD incre-
ments Ay, approximately equal to dy/dt, the results of BOD measurements can
be marked on the graph in the coordinate system:  log dy/dt versus t.  The
slope of any straight line section drawn through the marked points indicates
one of the coefficients bn, kn, bs or kg.  Also the values of t^, t2 and t3
can be easily read out from this graph.  The final carbonaceous BOD of the
tested solution can be calculated on the base of BOD recorded at the moment
t3, equal y^ and the maximum value of log dy/dt at the moment t?, equal zmax.
According to the above written equations, this maximum value z    is equal:

     zmax = log 2.303 L3 kg, thus:  L3 = .^ fc   - 10Zraa*

     The final carbonaceous BOD L  amounts to the sum of BOD measured up to
moment t, and BOD residual at the moment t?, so
     L  = y  + U, and L  = y_ + _ 1    .l
      c    3    3       c    3   2.303 ks
The value /„ is recorded and the values k  and z    are read out from the
graph, so the value of L  can be calculatid.    max

     In certain cases, when the nitrification phase F was superposed on the
phase E, the recorded BOD data were corrected by substraction of theoretical
oxygen demand for nitrification NOD from the recorded BOD data:

          NOD = 3.2 •  A NO  + 4.3 A NO , where

A N02 and A N03 are the analytically determined increase of nitrites and
nitrates contents (expressed as mg/1 N) .

     If the final carbonaceous BOD L  was determined in the series of samples,
each containing different initial concentration c  of tested substance, we
can make the graph presenting the dependence of L  on c  (Fig.  4).

     The slope of the straight line drawn through the marked points indicates
the unit oxygen demand of tested substance L , i.e., the amount of oxygen
needed by the solution containing 1 mg/1 of the tested substance.  L  is
expressed in mg 02/mg substance.  Apart from the mean value of L  , the
confidence limits 95 percent were always calculated following the Bartlett's
equation.  The intercept of the straight line indicates the oxygen demand
caused by organic components of nutrient medium and by the inoculum used in
the test.

     It should be stated that in special cases, the shape of BOD curve differs
from the above given pattern.  For example, if the tested substance is as
easily biodegradable as organic components of the nutrient medium are, the
phases D and E are superposed on the phase B and C, i.e., the decomposition
of the tested substance proceeds simultaneously with the decomposition of
nutrient medium components.  If the tested substance is not biodegradable,
the phases D and E do not occur at all.
                                     28

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Figure 4.  The dependence of final carbonaceous BOD L  on the initial
           concentration of the tested substance c .
The Tested Substance Decomposition

     In some tests, the tested substance contents were analyzed every day in
subsequent samples, initially identical.  (BOD was also recorded.)

     On the graph z = log dy/dt versus the time the supplementary values of
log c were added (where c is the tested substance concentration at the
moment t).   It allows to confirm that BOD process during the phase D and E
is corresponding with the decrease of the tested substance contents.  The
slope of the straight line log c = f(t) is also the kinetic coefficient of
tested substance decomposition kg.

     In the cases when ammonia was one of the final products of tested sub-
stance decomposition, the values of log   N£   were marked versus the time

(where N.p means final NH_ contents and N s"eans NH^ contents at the moment t) .
The slope of this line also indicates the kinetic coefficient kg.

The Choice of Parameters Characterizing the Biodegradability

     Practice shows that many of the above described parameters are not use-
ful to characterize the biodegradability of tested substances.  The reason is
that their values depend on the properties of the inoculum used in the tests,
and the control of these properties is very difficult.  Even if the source
of the seed is always the same (e.g., the wastewaters sampled from the same
municipal sewage system), the quantity and kind of sewage microorganisms
                                     29

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highly differs in different samples.  As the results of experiment should
describe the properties of tested substance and not the random conditions of
the test performing, it was necessary to choose those parameters which are
reproducible.

     It was found, that the best reproducibility can be obtained when the
relative parameters were chosen, namely, the differences or the ratios of the
parameters corresponding with the tested substance and the standard nutrient
medium biodegradation.

     Thus, the influence of a given substance on the microbiological activity
can be determined by the calculation of the inhibition period of the nutrient
medium biodegradation.  If t^(0) and t^(co) denote the moments of maximum
rate of nutrient medium decomposition, respectively in the blank sample not
containing the tested substance and in the sample containing initially the
tested substance at the concentration co, the inhibition time Atj is equal to:


                    Ati = Vco> - h^

     The inhibiting influence of various concentrations of the tested sub-
stance on the yeast extract or glucose decomposition can be described by the
graph At-, = f(c_).  The examination of this graph allows one to conclude
whether a given substance inhibits the microbiological activity and if so,
at what concentration it does.

     The biodegradability of the tested substance can be determined by com-
parison with the biodegradability of nutrient medium components.  The first
method is to calculate the inhibition time of tested substance decomposition
At2-  It is equal to:
where t.r(co) is the moment of maximum rate of the tested substance decompo-
sition in the sample containing the initial concentration c , and t-^(O) is,
as formerly, the moment of maximum decomposition rate of the yeast extract
or glucose in the blank sample.
     The data obtained in experiments with various initial concentrations CQ,
allow to prepare the graph At2 = f(c ).  Examination of this graph leads to
the conclusion how much the given substance is more difficult to biodegrade
than the standard substance.

     Another method is to calculate the ratio r of the values k corresponding
respectively with the tested substance decomposition and the decomposition of
the nutrient medium components:

                        k (c )
                    r =  s  °
                        kn(0)   ,

 where  ks(c  )  is the value of k  coefficient read out from BOD graph,
 corresponding with the phase E  of the process in the sample containing
 initial  concentration co.  The  kn is the k value read out from the BOD
 curve, phase  C, concerning the  blank sample  (co = 0).

                                     30

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     As formerly, the dependence of r value on c  value can be presented
graphically.  If r = 1, we can conclude that the tested substance is decom-
posed at the same rate as organic components of the nutrient medium (after
certain period of microorganisms acclimatization).  If r < 1, the biodegrada-
tion of tested substance is slower, and if r > 1, it is faster than the bio-
degradation of the nutrient medium components.

BIODEGRADABILITY IN THE RIVER WATER

     The only information gathered during the experiments with the river model
was the results of determination of the tested substance concentration during
the tests.  In several cases this information was supplemented by the data of
NH?, NC>2 and NO, contents during the tests.

     It was found that the process of specific organic compound decomposition
in the river water can be divided into three phases.  In the first phase, the
decomposition is slow or does not occur.  This lag phase corresponds with the
period of acclimatization of microorganisms to the presence of the given sub-
stance.  In the second phase, the decomposition of the tested substance pro-
ceeds at the approximately constant rate:

              v = -dc/dt = const.

     In the third phase, when the concentration c of the tested substance
drops down below certain critical value, the decomposition proceeds at a
decreasing rate and the concentration c decreases asymptotically to zero.
The process in this phase usually could not be exactly observed, because the
concentrations were close to the detection limit.

     The above given pattern of process is illustrated by the typical graph
of a tested substance decrease in the river water as shown in Fig. 5.

     As the parameters characterizing the biodegradation of tested substances
in the river water, the following ones were chosen:

     - the time of lag phase t
     - the decomposition rate v during the constant rate phase.

     The values of the above given parameters can depend on the kind of micro-
organisms living in the river water used in the tests.  However, it can be
assumed, that they are adequate to comparatively study the fate of all tested
substances in the river water.

TREATABILITY DATA

     In the treatability tests, the inflowing wastewaters and the effluent
from the activated sludge unit were analyzed.  The determined parameters were:
COD and tested substance content.  Additionally, the MLSS (dry mass), the
retention time and D.O. content were controlled.
                                     31

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               c, mg/l
                                           v=const
                  log phase
                             constant
                           -velocity_£hqse\velocity
                                                   the phase  of
                                                  1 decreasing
                                                          time, days
Figure 5.   The typical  curve  of  the  decomposition of a specific organic
           compound in  river  water.
     The simple method of treatment  efficiency characterization is the cal-
culation of coefficient K,  defined as below:
                           -  c.
                    K =
                                   mt
                                     r-
where:
- c  and c  denote the concentration  of  the pollutants in the inflowing
  wastewaters and the effluent,  respectively, mg/l
- m denotes MLSS in the aeration chamber,  g/1
        - t.r is the retention time,  hours

     The treatment efficiency coefficient  K determines  the  treatability of a
given substance by means of activated sludge,  and  its value is approximately
independent from the technological parameters  of treatment  process  (MLSS and
retention time).

     In the present work two values  of K coefficient were calculated:  the
value K , corresponding with the tested substance  removal,  and the  value
characterizing the overall treatability of wastewaters.  In this  last  case,
the COD values of the inflow and of  the effluent have to be substituted into
the above equation for c  and c .
                                      32

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     Usually, when c  was increased, the values KCQD and Kg decreased, but
after certain time t°, KCOD reached a stabilized level.   Similarly, the value
KS reached the constant level after the time t2.  The values t-^ and t2 deter-
mine the time of sludge acclimatization which restores the normal activity of
microorganisms at the time t-^ and makes the microorganisms able to decompose
the tested substance after the moment t2.

     As characteristics of the treatment process, the following parameters
were presented:

     - times of acclimatization t-^ and t2
     - overall treatability coefficient KQQQ
     - the specific substance treatability coefficient Kg.

     All these characteristics are the functions of tested substance content
in the inflow c .

TOXICITY TESTS

     The 50 percent lethal concentrations LC50-96 h or 24 h were calculated
by use of the "probit" method.  This method of calculation is based on the
assumption that the mortality of the test organisms is a Gaussian function of
the logarithm of the toxicant concentration.  So, the observed mortality were
marked on the probability paper versus the logarithm of tested substance con-
centration and the best fitting straight line was drawn.  LC5Q value was read
out as the abscissa, corresponding with the value of ordinate equal to 50 per
cent.  To present the results of mortality determinations, the empirical
points were marked in the coordinate system:  mortality (%) versus the tested
substance concentration, and next the best fitting log normal distribution
curve was drawn.

SUPPLEMENTARY TESTS

The Tests of Volatility

     According to the Henry's law, the concentration of a given substance in
gaseous phase c  is proportional to the concentration of this substance in
the liquid phase C]_:               eg = a  •  Ci

     If a volume dVa of the air is buobled through a volume Vw of solution,
the decrease of volatile substance concentration in the liquid is:

          dcx = - cgdVa/Vw, or:  dc-^^ = -a dVa/Vw.

At the same time, the bubbling of the air causes the evaporation of dVw, the
volume dVw of water, equal to:
       0.018  is the molecular mass of water kg/mole
       24  is  the molar volume of water vapor at the test temperature  22
       and at the normal pressure 760 mm Hg
                                     33

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     - 20 is the partial water vapor pressure at the test temperature mm Hg
     - 760 is the atmospheric pressure, mm Hg

     The rearranging of these equations leads to:

     dc,            _       dvw         cj                       V
     —L = 50.7 x 103 x a x -y-  or log —  = 50.7 x a x W6 log ^f-  ,
      cl                      w          o                        o

where c0 and VQ are the volatile substance concentration and the liquid volume
at the beginning of the tests.

     The results of the determinations of c-^ and the weighing of the solution
giving V^ values are marked on the graph log c^ versus log V'.   The slope of
the obtained straight line equals the factor 50.7 x 103 x a,Wso the value a
can be calculated.                                                        ~~

     The blowing off rate of the volatile, but not biodegradable substance,
from the aeration chamber can be calculated with use of mass balance equation:

          co '  Vw = ce '  Vw + Va •  cg ,  where

     - V  and V  are the volume rate of inflowing wastewaters and the air
       1/h.
     - CQ, ce and c  are the volatile substance concentration,  respectively
       in the inflow, in the effluent and in the air flowing off the chamber.

     As c  = a-ce, the volatile substance concentration in the  effluent is
equal:
                              c
                               o
                                     34

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                                   SECTION 7

                           RESULTS OF BIODEGRADATION

METHYLETHYL KETONE, MEK

Respirometric Measurements

     Three series of experiments were made.  In the first series, BOD was
measured by means of Sapromat.  The samples contained the nutrient medium
(yeast extract) with various MEK additions within the range 0 - 800 mg/1.
The test solutions were inoculated with municipal wastewater.  In the second
series, both BOD and MEK content changes were observed in the samples with
initial MEK concentration equal 200 mg/1.  After the second test was
completed, the third series was carried out with the same conditions except
that the solution remaining from the second test was used as inoculum (test
with the microorganisms acclimatized to the presence of MEK).

     In the first series, in which different initial concentrations of MEK
c0 were applied, the phase of nutrient medium decomposition was superposed on
the phase of MEK decomposition.
are presented:
     - final carbonaceous BOD  (L(
In Figs.  6, 7 and 8 the following relations
 as function of initial MEK content c0)
     - the time of process inhibition Ati as a function of CQ

     - the ratio r of the coefficient of MEK decomposition k  to the
coefficient of nutrient medium components k .
             2000
             1500
             1000
              500
Figure 6.  The final carbonaceous BOD L  as function of initial MEK content cc
                                       c                                     ^*
                                       35

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 1.5
 1.0
 0.5-
     A todays
         200
                400
                     660
                               800   .
                               c0. mg/IMEK
                                                 r = ks/kn
                          200
                                                           400
600     80C
     c0, mg/l MEK
   Figure 7.   Lag phase duration At-,
              as function of c0.
                                        Figure 8.  Dependence of  the  ratio r
                                                   on initial MEK concentra-
                                                   tion cQ.
400

300

200-

100

 0
BOD. mg/l 03
—   	MEK    x-


   2nd test    )/

     ja^/\
     c. mg/l MEK

        200
3rd test
      1   23450
        100
                         1234
                              time, days
  Figure  9.   Decrease of BOD and MEK during    Figure  10.   Linearized BOD curve
              the  respirometric test.                       from Figure 9.


       The results  of the second and third series  are presented graphically in
  Figs. 9 and 10.

  Discussion

       It may be  assumed that the basic reaction of MEK biodegradation follows
  the equation:

            CH3.CO.C2H5  + ii 02	»• 4 C02 + 4 H20

       The stoichiometric value of oxygen uptake in the above given process of
  MEK oxidation amounts  to 2.44 mg 02/mg MEK.  The experimental value (Fig. 6)
  was determined  as  equal to 2.12 ±0.05 mg 02/mg MEK.

       Comparing  of  experimental and stoichiometric values  leads to the con-
  clusion that ca. 87%   of MEK is mineralized and the  resting 13% is assimilated
  by microorganisms  to produce the biomass.
                                         36

-------
     Determination of inhibition time  of biochemical processes  in  the pres-
ence of MEK leads to the conclusion that MEK at  a concentration of 100 mg/1
and above causes the inhibition of the microbiological  processes during  1  day
in comparison with the process in the  blank sample.

     The coefficient ks of monomolecular reaction of MEK decomposition
decreased at the initial MEK concentrations of 200 mg/1 and above.   The
reason may be that at higher MEK concentrations  the mineral nutrients may  not
be adequate, thus slowing the process.

     The acclimatization testing showed that the previous adaptation of  the
seed used to inoculate the sample significantly  shortens the lag phase.

Biodegradation in the river water

     The results of MEK biodegradation in the river water are presented  on
Fig. 11.  The right side of the graph  presents the MEK  content  changes
after the repeated addition of MEK to  the water  in which the first portion
of MEK was decomposed (i.e. to the water containing acclimatized micro-
organisms) .
             c. mg/l  MEK
                                                 t0=0
                                                                T
                                                        time, days
 Figure 11.  The decomposition of MEK in river water.
     It is visible that MEK is easily biodegraded by the microorganisms
living in the river water, especially when they are previously acclimatized
to MEK.

Treatability tests

     During the experiments two activated sludge test units and one control
unit were operating in parallel  The first was fed with wastewater containing
200 mg/1 MEK; the second one 400 mg/1 MEK.  The results of MEK content in the
effluent and the results of calculations of the overall treatability coeffi-
cient K    are presented in Figs. 12 and 13.
     It is visible that MEK is easily removed from the wastewater after
acclimatization of the activated sludge, lasting 8 to 9 days.  The waste-

                                      37

-------
  c«, mg/l MEK
 0      2   3      5  6  78
                                         OA

                                         0.3

                                         0.2'
                                           KCOD'9~'''h~
                                                          width ot contidenee strip
                                                          \Z      c.=200mgVlMEK
                       c.=400mq/lMEK
                                                          C0=0i control chamber
Figure 12.   MEK removal by activated
             sludge.
 0123456789   10
                             time, days

Figure 13.  The  treatability coeffi-
            cient  KQQP of wastewater
            containing MEK.
water treatment  (COD removal) is practically independent from MEK content
in the inflow.   The differences between  KCOD values in the control unit ai
in the test units were statistically not significant.

DIMETHYL AMINE,  DMA
Respirometric measurements

     Seven series  of measurements were made.   In the first three  series
different initial  DMA concentrations were  applied,  whereas in the remaining
series, the  samples contained initially the same DMA concentrations.

           TABLE 6.   THE CONDITIONS OF RESPIROMETRIC MEASUREMENTS
                      OF DMA BIODEGRADABILITY
Number of
No. samples in
the series
I
II
III
IVa
IVb
V
VI
VII
5
6
8
4
4
9
6
5
Test
duration, Nutrient
days medium Seed
18
12
13
5
5
11
7
8
yeast extr. sewage
yeast extr. sludge
glucose sludge
" sludge
" adapted
sludge
" sludge
" sludge
" sludge
Range of
concentration,
mg/l
0 - 135
0 - 270
0 - 900
180
180
170
185
180
                                      38

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     The exemplary curves of BOD, DMA decrease and NH3 increase are shown in
Fig. 14 (the data resulting from series V).  On Fig. 15 the same data are
presented in the linearizing coordinates system.
                                                           BOD, mq/l 02
        c, mg/l N-NH3
               c, mg/l DMA
                                                BOD of nutrient medium
Figure 14.  BOD curve, DMA decrease and NH3 increase during the respiro-
            metric test.
                                                     8    9    10
                                                        time, days
 Figure 15.   The curves from Figure 14 after linearizing transformation.
                                      39

-------
    final carbonaceous BOD,
           Lc, mg/l02
            100
                      200       300
                    initial DMA concentration,
                        C0, mg/t DMA
                                           2.5'
                                           2.0
                                           15
                                           1.0
               sample with the
               adapted seed
                            time, days
 Figure 16.  The final  carbonaceous BOD   Figure  17,
             Lc as function of initial
             DMA content  c^.
Figure 18.  The  inhibition time of
            glucose  decomposition
            and  of DMA decomposition
            At2  as function of the DMA
            initial  content c~.
                                            1.0
                                           06
                                           0.4
                                           02
                                              =ks/kn
                                                 X
Figure 19.
             The influence of the seed
             acclimatization on the  DMA
             biodegradation process.
                                                          /correlation coeticient 046 «
                                                           (not significant)
                                                                  X
                                                       100
                                                                 200
                                                                            300
                                                       The  dependence of the
                                                       ratio  r on the initial
                                                       DMA  concentration c.
     The  dependence of final carbonaceous  BOD L  on the initial DMA concen-
tration c0  is  exemplified in Fig. 16  (data obtained in the II series).   The
mean value  of  LC calculated from data obtained in all 7 series was  equal to
1.56 +0.05  mg  02/mg DMA.   The ammonia produced in the biodegradation of DMA
Nu calculated  in a similar way was NU =  0.21  +_ 0.006 mg NH3-N/mg DMA.   Fig. 17
presents  the results of biodegradation tests  in which the samples were  seeded
with non-acclimatized and acclimatized inoculum to DMA.
     The data  obtained in all 7 series were  marked on the graphs in  a  similar
way, and the moments  of maximum BOD t-L and t2  were read out.  Next,  the
time of inhibition  of the nutrient medium decomposition Atj was calculated
and presented  in  Fig.  18 as the function of  initial DMA contents c  .   In the
same Fig. 18 the  inhibition time of DMA decomposition At2 is presented also.
                                       40

-------
Additional analyses of final DMA contents have shown that at initial concen-
trations up to 270 mg/1 DMA was completely decomposed;  whereas,  DMA decomposi-
tion at initial concentrations of 450 and 900 mg/1 proceeded more slowly.

     The velocity of DMA decomposition in comparison with the velocity of
yeast extract or glucose decomposition is characterized by the values of r,
defined as r = ks/k , where ks is the coefficient of DMA decomposition, kn is
the coefficient of ^composition of glucose or yeast extract.  The dependence
of r on initial DMA concentration co is shown in Fig. 19.

Discussion

     According to the equation of DMA oxidation:   (CH3)2NH + 302	«- 2C02 +
2HoO + NHx  the unit oxygen uptake should amount to 2.13 mg 02/mg DMA, and
the unit  ammonia involved  should be Nu = 0.31 mg N/mg DMA.  Comparison of
this last value with experimentally determined Nu  = 0.21 leads to the con-
clusion that approximately 2/3 of DMA content is mineralized according to
the above equation and  1/3 is assimilated by the microorganisms.

     The  experimentally determined value of unit oxygen  demand Lu is equal  to
1.56 in comparison with the stoichiometric value of 2.13 mg 02/mg DMA.  There-
fore,  the most probable summary reaction equation  is as  follows:

            2/3 mg  DMA  1.42  mg 02_  0<25 mg NH3 + 1.3 mg C02 +  0.53 mg H20
                        <"+ energy

                        0.14  mg 02_
            1/3 me  DMA  	T~-—I"**  biomass  +  byproducts
            1/0 m&  U1U^  +  nutrients               r

     The  ratio  of assimilated nitrogen  coming from DMA to the final BOD  is
 equal  to  1  mg NH3-N:15 mg  02 which is near to the value of  N:BOD ratio
 optimal in the treatment  process.

      The results of BOD determination show that DMA at concentrations up to
 270 mg/1 do not  inhibit the microbiological activity which  is proved by the
 horizontal course of graph At].. = f(c0)  (Fig. 18).  The DMA decomposition
 proceeds with some delay which increases as the initial DM content increases,
 Additional analyses of final DMA content show that at co = 450 and co = 900
 the DMA decomposition was strongly inhibited during all 13 days of testing.

      The ratio of DMA decomposition coefficient to the coefficient corre-
 sponding to the nutrient medium decomposition is ca. 0.75 and it depends
 just a little on the DMA contents within the range of co 0 - 270 mg/1 (the
 dependence is statistically not significant).  Therefore, it can be stated
 that DMA biodegradation after a certain time of microorganisms acclimatiza-
 tion proceeds with a velocity not much lower than the velocity of nutrient
 medium decomposition.

      The acclimatization  of the inoculum to the DMA shortens the inhibition
 periods  ca. 0.5 day in comparison with the biodegradation process without
 acclimatization.  Beyond  this, the process is very similar in both cases.


                                      41

-------
              c0, mg/l DMA
                                                '=0.56mg/l-h
            0    1
                                                235
                                                         time, days
 Figure  20.   The  decomposition  of DMA in river water.
       TABLE  7.   KINETIC  PARAMETERS  OF  DMA BIODEGRADATION  IN  RIVER WATER
                                Lag phase to,
                                   days
Decomposition
velocity (v),
   mg/l-h
          Without acelima-
tization
After acclimati-
zation
1.3

0.8
~ 0.4

~ 0.55
Biodegradation in the river water

     During the test, the DMA content was measured.  When DMA content had
decreased down to zero, the next dose of DMA was added once more to the same
solution (adaptation test).  The results are presented in Fig. 20.  The
kinetic parameters read out from the graph are gathered in Table 7.  The
data show that DMA can be biodegraded in the river water during several days
The process is advanced and accelerated by previous acclimatization of micro-
organisms to the DMA.

Treatability tests

     Three series of experiments were made.   In the first series the acti-
vated sludge unit was fed with wastewater containing 20 mg/l DMA.   In the
second series two activated sludge units were operating in parallel (DMA
content in the inflow was 45 and 90 mg/l during the first week and changed
to 90 and 135 mg/l,  respectively).   In the third series one unit was fed with
wastewater with 90 mg/l DMA; the second one with 135 mg/l DMA
                                     42

-------
                 ig/L DMA     t
            0   1   2  3   4   5  6  7  8   9   10  11  12  13  14  15  16  17
Figure 21.  DMA removal by activated sludge.
                         control chamber
                             c.=135 ma/1 DMA
             0   12  3     5  6   7   8  9  10  11  12 13  14  15  16  17
Figure 22.  The treatability coefficient KCOD of wastewater containing DMA.
     The results of DMA removal determinations and the calculations of the
overall treatability coefficient KCOD are presented in Figs. 21 and 22 (third
series).

     On the basis of these graphs, as well as of the data obtained in the
remaining series, the following conclusions can be made.

     - The overall treatability, characterized by the value of K^QQ, did not
depend on the DMA content (within the period of K^Qp value stabilization after
acclimatization of the sludge).  The differences of these KCQD values
corresponding with the control unit and two test units were statistically
not significant.

     - The DMA treatability after several days of sludge acclimatization was
high and no DMA could be detected in the effluent at DMA content  in the inflow
c0 up to 135 mg/l and with a retention time of 4 hours.  However  at the very

                                     43

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short retention time (1 hour) and at c0 equal to 90 and 135 mg/1, the effluent
contained measurable quantities of DMA which enabled one to calculate K™UA
value equal to 2.0 g^-l-h"1.                                          UMA

     - The acclimatization of the activated sludge is characterized by the
values t^ of the time necessary to stabilize the COD removal rate after any
increase of DMA content in the inflow and by the value t2 required for DMA
removal rate stabilization.  These values are gathered in Table 8.

       TABLE 8.  THE COURSE OF ACTIVATED SLUDGE ACCLIMATIZATION TO DMA
Series
I
I la
after co increase
up to ...
lib
after co increase
up to ...
Ilia
Illb
DMA in inflow
c0, mg/1
20
45
90
90
135
90
135
Time t1}
days
-
5
3
5
4
15
14
Time t2,
days
6
5
0
6
0
10
12
         TABLE 9.   THE CONDITIONS OF THE RESPIROMETRIC MEASUREMENTS
                   OF DMF BIODEGRADATION

Number of
No. samples in
the series
I
II
III
IV
V
VI
VII
4
4
6
6
6
6
6
Test
duration
days
10
9
7
9
8
9
6
Range of
, Nutrient concentration,
medium Seed mg/1
yeast extr. sludge
glucose sludge
" sludge
" sludge
" adapted
sludge
" sludge
" adapted
sludge
0 - 440
0 - 440
145
145
145
290
290
                                     44

-------
                             c, mg/l NH-,
                       BOD mg/l 02
150
                         6   7
                           time, days
                                                ; logc
                                                    DMF;
                                            log-^-
                                             9N,-N
                                           01
                                                                       k=Q6
       2345678
                          time, days
 Figure 23.  BOD curve, DMF decrease
             and NHg increase during
             the respirometric test.
Figure 24.  The curve from Figure
            23 after linearizing
            transformation.
 DIMETHYL FORMAMIDE,  DMF

 Respirometric measurements

      Seven series of tests were carried out.   In two series,  BOD of the
 samples with various DMF content was measured.   In the other series, just one
 DMF concentration was used but the measurements consisted of BOD, DMF, NH3,
 N02 and N03 determinations.  The conditions of the tests are given in Table 9.

      The exemplary curves of BOD, DMF decrease and NH3 increase are given in
 Fig.  23 (the data coming from the third series).  The same data after the
 linearizing transformation are presented in Fig. 24.

      On the basis of the data obtained in all the series, the final carbona-
 ceous BOD LC was calculated.  The exemplary graph presenting Lc as a function
 of initial DMF concentration co is given in Fig. 25 where the final ammonia
 content is also marked.
      The mean value of unit oxygen demand related to the decomposition of
 1  mg DMF is equal  to:   LU = 1.40 ±0.02 mg 02/mg DMF.  The amount of
 ammonia produced in the process of the decomposition of 1 mg DMF is equal
 to:   Nu = 0.087 ±0.004 mg NH3-N/mg DMF.
      The influence of the previous acclimatization of the seed micro-
 organisms on the DMF decomposition kinetics is visible from Fig. 26 where
 the linearized BOD curves are marked:   curve I corresponds with the sample
 seeded without acclimated inoculum and curve II corresponds with the sample
                                      45

-------
  1000
            100
                 200   300
                           400   500
                               c0, mg/l DMF
             LC and the final ammonia
             content as a function of
             initial DMF content cn.
                                            20
                                            1.0
                                                      somple with not adopted seed
                                                   /sample with the adapted seed
                         789
                           time, days
 Figure 25.   The final carbonaceous  BOD    Figure 26.
             The influence of the
             seed acclimatization on
             the DMF biodegradation
             process.
    5  doys
X X \^
8 « * ^-^
X
1.0-
X
{*
	 0_- 0 \ 0

r = ks/kn
X
X
300 40°c, mg/D°SF 0 100 200 300 400 500
C0. mg/l DMF
Figure 27.  The  inhibition time of
            glucose  decomposition Atj_
            and  of DMF decomposition
            At2  as a function of the DMF
Figure 28.  The dependence of the
            ratio r on  the initial
            DMF concentration co.
            initial  content co.
seeded with solution  remaining from the former sample.

     The: DMF decomposition kinetics are characterized by  the curves presented
in Figs. 27 and 28.   In  Fig.  27 two curves are presented,  both curves being
calculated on the basis  of data coming from all 7 series,  and representing
the following:
                                       46

-------
     - the dependence of inhibition time At-, of nutrient medium decomposition
on the initial DMF concentration co.

     - the dependence of inhibition time At~  of DMF decomposition on co.

In Fig. 28 the ratio r of the coefficient ks of DMF decomposition to the
coefficient kn of nutrient medium decomposition in the blank sample is
plotted versus c .

Discussion

     Assuming that the basic reaction of biochemical oxidation of DMF
follows the summarizing equation:

          H.CO.N(CH3>2 + 7/2 02 . - ». 3 C02 + 2 H20 + NH3

we can calculate the stoichiometric oxygen uptake as equal to 1.53 mg 02/
mg DMF, and the unit ammonia production equal to 0.19 mg NH^-N/mg DMF.

     The measured unit oxygen uptake was equal to 1.40 mg 02/mg DMF which
corresponds to 90 percent of the stoichiometric value.  The unit ammonia
production was measured as equal ca. 0.09 mg NH3-N/mg DMF, i. e. a little
less than 50 percent of stoichiometric value.  This last figure shows that
the ratio of nitrogen assimilated by microorganisms to the carbonaceous BOD
is equal to ca. 1:14 (mg N:mg 62) which is near to the optimal ratio in the
activated sludge treatment.

     The determinations of the kinetic parameters lead to the conclusion
that DMF at concentrations up to 440 mg/1 do not affect the nutrient medium
biodegradation which is proved by the horizontal course of straight line
    = 0 (Fig. 27).
     The inhibition time of DMF decomposition At2 changed irregularly.  Up
to DMF concentration 300 mg/1 this inhibition time was equal to ca. 3 days
and at the concentration of 440 mg/1 this time increased up to 4.5 days.
At all concentrations tested, the DMF decomposition was always complete,
i.e. no final DMF content was measurable.

     The previous acclimatization of the seed microorganisms to the DMF
presence shortens the inhibition time of nutrient medium biodegradation
(t^ is average 3.5 days shorter) as well as DMF biodegradation (tj is
average 3 days shorter) .

     The monomolecular reaction rate coefficient ks of DMF decomposition
amounts to 80 percent of kn value corresponding with yeast extract or
glucose biodegradation.  Therefore, it can be stated that except for a
period of delay needed for microorganisms acclimatization, the biodegra-
dation of DMF processes is not much slower than the decomposition of above
mentioned standard substances.
                                     47

-------
         c,
       10-
         01     2  t  3     A     5    frt)    1      23
                                                        time,  days

Figure 29.   The decomposition of DMF in river  water.
Biodegradability in the river water

     Three series of measurements were made.   In the  first  and  second  series,
the DMF was added to the fresh river water.   The initial  DMF  content was
equal to ca.  30 mg/1.  The third series consisted of  the  repeated addition
of DMF to the water in which DMF was completely decomposed  during the  second
series, i.e.  to water with acclimatized microorganisms.   The  results of the
second and third series are presented in Fig.  29.

     The tests without acclimatized microorganisms gave the following  results
(mean of the values from first and second tests):

     - lag phase t  = 2 days

     - the degradation rate v = 0.5 mg/l:H

     The test with previously acclimatized microorganisms showed the fol-
lowing results:
                                    48

-------
      -  lag phase to ~= 0

      -  the degradation rate  v = 0.8 mg/l-h

      These values prove  that DMF is easily biodegraded in the river water,
 but it  needs a certain period of microorganisms  acclimatization.

 The treatability tests

      One test lasting 42 days was made in which  wastewater containing  70  mg/1
 DMF was treated.  The results of DMF determinations in the effluent and the
 values  of overall treatability coefficient KCQD  are given graphically  in
 Figs.  30 and 31.
                                           •=4h .,  _tr=4h
                       DMF concentration in the inflow c.=73
             • 2 £  6  8 10  12 14  16 18  20 22 24  26 28  30 32  34 36

Figure 30.   DMF removal by activated sludge.
              "40 "42  44
                time,  days
          0.5
            KCOD- 9
                   ''~
n/

0.3
02

0.1
0
T
K
1\
J\
\C0=73 mq/l DMF J_\


f* T
\
< /

^\\ /width ot confidence
^\/ strip

           0  2  4  6  8 10 12  14 16  18 20 22 24 26 28 30 32 34 36 38 40 42 44
                                                             time, days
Figure 31.  The  treatability coefficient
of wastewater  containing DMF.
                                       49

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       TABLE 10.  THE CONDITIONS OF RESPIROMETRIC MEASUREMENTS OF PNP
                  BIODEGRADABILITY
Number of
No. samples in
the series
I
II
III
IV
V
VI
VII
5
5
5
6
6
3
3
Test Range of
duration, Nutrient concentration,
days medium Seed mg/1
10 glucose wastewater
15 " "
5 " "
5 " "
4 ii ii
3.5 yeast extr. not adapted
wastewater
3.5 " adapted
wastewater
0 - 100
0 - 100
0-80
30
30
70
70
It is visible that 35 days was necessary to acclimatize the activated sludge
to DMF.  After this period DMF was removed almost completely from the
wastewater.

     During the acclimatization period, the overall treatability coefficient
KCOD was much l°wer than the value corresponding with the control unit, but
after this period the KCOD value increased and any influence of DMF on the
wastewater treatment was not observable.

PARA-NITROPHENOL, PNP

Respirometric Measurements
     Seven series of tests were carried out.   The conditions of the
tests are given in Table 10.

     The exemplary curves of BOD and the decrease of the PNP content are
given in Fig. 32.  The same data, after linearizing transformation are
plotted in Fig. 33.

     The unit oxygen demand Lu can be read out from Fig. 34 in which the
data coming from the second series are plotted.

     The mean value, obtained on the basis of all data was equal to:  Lu =
1.04 ±0.12 mg 02/mg PNP.

     The amount of developed mineral nitrogen (mainly as N03)  was equal to
ca. 50 percent of the nitrogen bound in PNP.
                                      50

-------
   c, mg/f PNP
                           BODf mg/102
                                130
                                     50
                                                  Figure  32.
BOD curve and
PNP content dur-
ing the respiro-
metric test.
                           time, days
 1.8-
 1.4'


 1.0-


 Q6


 0.2-

  0
log
       c    A,  log c
                            k=1.2 d'
              2345
                           time, days
Figure 33.  The curves from Figure 32
            after linearizing trans-
            formation.
                                                      Lu=1.03 mgO^/mg PNP
                                                 10      20      30     40
                                                initial PNP concentration. c0,
                                                                mg/l PNP

                                       Figure 34.  The final carbonaceous
                                                   BOD Lc as a function of
                                                   initial PNP content c0.
     The influence of the seed acclimatization  on  PNP  biodegradation is seen
in Fig. 35 in which two curves are drawn, corresponding  to  the  samples inoc-
ulated with and without acclimatized seed.

     The mean values of the inhibition  time of  the nutrient medium decompos-
ition in the presence of PNP Atj are graphically presented  in Fig.  36 as a
function of initial PNP content co.  On the same graph,  the mean values of
the inhibition time of PNP decomposition At2  are plotted also.

     The mean values of the ratio r of  the coefficient ks to the coefficient
kn (corresponding with PNP and nutrient medium  biodegradation)  are plotted
versus the initial PNP content co (Fig. 37).
                                      51

-------
 150
                                         Figure 35.   The influence of the seed
                                                     acclimatization on the
                                                     biodegradation process.
                            time, days
                                             r=ks/kn
   5.0

   4.0

   3JO-

   2.0-

   1JO
   0
       , Atj ; days
                    so
Figure 36.  The inhibition time of
            glucose decomposition Atj
            and of PNP decomposition
            At 2 as a function of the
            PNP initial content c.
Figure 37.  The dependence of the
            ratio r on the initial
            PNP concentration co.
Discussion

     It was found from the experiments that  around  one  half of the nitrogen
bound in PNP is converted to nitrates.  However,  the  calculations of unit
oxygen demand were based not on the total  BOD but on  the  final carbonaceous
BOD which is a more reproducible parameter.

     Therefore, the biodegradation of PNP  could be  expressed by the equation:
                                      52

-------
          HO.C6H4.N02 + 5 02	to. 6 C02 + H20 + NH3

According to this equation, the stoichiometric value of the final carbonaceous
BOD equals 1.15 mg 02/mg PNP.  The experimentally determined value (corrected
by substracting nitrogen oxygen uptake) was equal to 1.04 ±0.12 mg 02/mg PNP,
i.e. nearly 90 percent of the stoichiometric value.  It should be noted that
the total BOD of PNP is somewhat  higher.  If one half of the nitrogen bound
in PNP is converted to N03 and the rest is assimilated, the experimental unit
oxygen demand would be ca. 1.3 mg 02/mg PNP.

     The determination of kinetic parameters allows one to conclude that PNP
concentrations up to 80 mg/1 inhibits glucose biodegradation just a little.
However, at the initial PNP amount co = 100 mg/1, the inhibition of glucose
biodegradation was distinctly marked (4 days of inhibition period).  This
proves that at this concentration PNP is toxic for the microorganisms.

     At a low PNP content  (up to 50 mg/1), the PNP biodegradation proceeds
almost simultaneously with the nutrient medium decomposition.  At PNP content
within the range  from 50 to 80 mg/1, the PNP biodegradation was inhibited
during 2 days, and at 100 mg/1 PNP was almost resistant.

     Once the microorganisms are acclimatized to the PNP presence the PNP
decomposition proceeds fast.  After the inhibition period, which is necessary
to microorganisms acclimatization, the ratio r of kinetic coefficients
corresponding with PNP and glucose decomposition ranged from 1.0 to 2.5, i.e.
PNP was decomposed faster than glucose was.

     The previous adaptation of the seed shortens the inhibition time about
0.5 day.

Biodegradation in the river water

     Four series of tests were made, each with use of three installations,
operating in parallel, everyone with another PNP addition.  In every series,
PNP was repeatedly added  at the moments  in which the former PNP dose had
been completely decomposed  (acclimatization testing).

     Figure 38 presents exemplary  results of PNP biodegradation in the river
water  (third series).

     On the basis of the  data coming from all four series, the mean values
of  inhibition time to and the decomposition velocity v were calculated and
are shown in Table 11.

     The  data in the table show that PNP is easily biodegraded in  the  river
water, especially after the  acclimatization of river water biocenosis  to the
PNP.   It was observed that  at low  concentrations,  e.g., 5 mg/1, the PNP bio-
degradation proceeds more slowly than  at the higher  concentrations.
                                      53

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          20
              1234501  23450


Figure 38.  The decomposition of PNP in river water.
1   234567
            time, days
     TABLE 11.  KINETIC PARAMETERS OF PNP BIODEGRADATION IN RIVER WATER
After PNP
addition
Initial PNP
content c ,

mg/1 PNP
5
10
15
20
to the
river
V
mg/l-h
0.1
0.18
0.35
0.35
fresh
water
t
days
0
0.6
1.3
1.4
After repeated
PNP addition
v t
mg/l-h days
0.16 0
0.43 0
0.48 0
0.45 0
After subsequent
PNP addition
v t
mg/l'h days
0.28 0
0.53 0
0.50 0
0.48 0

Treatability Tests

     The tests were carried out with use of two activated sludge units
operated in parallel.  The results of the determinations of PNP removal
are presented in Fig. 39.  On this graph CQ denotes PNP content in the
inflow and c  denotes PNP content in the effluent.
            C

     The curves in the graph show that non-adapted activated sludge removes
PNP with low efficiency.  After ca. 2 weeks of acclimatization, the PNP
removal efficiency becomes high and the effluent contains just traces of PNP.
                                     54

-------
c, mg/i PNP ist
Cor5 mg/l PNP
V^ ^ --—__-.

unit
c»=:10 mg/l PNPi C0=15 mg/ PNP

•> •>/. 9fi OR


                                                            ^
            c, m/l PNP
2nd unit
13
10

5

*--«^^^
C.-5 """"V Co = 20 mg/l PNP c«= 30 mg/l PNP c,=40 mg/l PNP


3 2
u
yie
s
v — ./"NN. *.


\

4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40 42 44
time, days
Figure 39.  PNP removal by the activated sludge.
     The overall treatability coefficient KCOD did not depend significantly
on the PNP presence in the wastewater.  KCQD value in the tests units was
almost the same as in the control unit.  Additional tests were made in which
the activated sludge, acclimatized during the former tests, was fed with
wastewater containing 200 mg/l PNP.  The results showed that after additional
three days of acclimatization to such PNP conent, PNP was removed at the
efficiency of 90 percent, Ks = 0.7 g'Al-h-1.

ORTHO-CHLOROPHENOL, OCP

Respirometric Measurements

     Four series of tests were carried out.  The first two series consisted
in  the BOD measurements in the samples containing nutrient medium with
various OCP  additions ranging 0 - 200 mg/l in the first series and 0 -
1200 mg/l in the second.  After these tests were completed, the residual
OCP content was determined and was found in all samples as equal to ca.
50 percent of the initial value.   It could be caused by biodegradation or
by the evaporation of OCP from the solution and by the absorption of OCP
vapors by the soda-lime absorbers with which the flasks of Sapromat are
equipped.  The aim of the third series was to determine this process of
evaporation.  The samples with the initial OCP content ranging 125 - 1240
mg/l were incubated in Sapromat at the same conditions as formerly, but
every day the flasks in Sapromat were open and small samples withdrawn for
analyses.  The soda-lime mixture was analysed also, but the opening of
flasks made the BOD record not feasible.  The results of this series
showed that all the OCP lost by the samples was found in the soda-lime
absorbers, and therefore, no biodegradation of OCP occurred.

     The fourth series aimed to determine whether OCP at small concentrations
of 5 and 10 mg/l is biodegraded.   The method was similar to the procedure

                                     55

-------
 used in the third series:  the flasks were open every day and OCP content in
 the samples and in the soda-lime was determined.

      The conditions of the tests performed are described in Table 12   The
 results of the first and second series enable  one to calculate the final
 carbonaceous BOD Lc of the samples with various OCP content.  Exemplary BOD
 curves are given in Fig. 40 (data coming from the second series).  The
 dependence of Lc on the initial OCP content c0 resulting from these BOD

 toTS 1AnnreS!"ted ^o^g- I1'  °n the last graPh> the P°ints corresponding
 to c? - 600 and c0 = 1200 mg/1 represent 11 days BOD because it was not
 possible to determine the final BOD in these cases.


       TABLE 12.   THE CONDITIONS OF THE TESTS MADE BY MEANS OF SAPROMAT
No.
I
II
III
IV

Number of Test R of
samples in duration, Nutrient concentration,
the series days medium Seed ma/1
6 14
6 11
5 19
11 11
* BOD. mg/l02
yeast extr. wastewater 0 - 200
0 - 1200
" 125 - 1240
0 - 10
Omq/l OCP, Lr=94
                                                      q/\ OCP. Lc=85
                                                    Q/t OCP. LC=7A
         0
                             5   6   7   8   9   10   12  13
                                                        time, days

Figure 40.  BOD curves of nutrient medium with various concentrations of OCP.

                                     56

-------
   BOD, mg/i 02
                  P-0.085mg02/mgPNP
              500
              1000   ,
                C0, mg/l OCR
Figure 41.
The final carbonaceous
BOD Lc as a function of
initial OCP content co-
                                            A »!, days
                                                          500
                                1000
                                c0< mq/l OCP
Figure 42,
The inhibition time of
yeast extract decomposi-
tion At^ as a function  of
the initial OCP  content CQ.
    109 c
          days
                 blank sample; kn=0.15 d

                   k=Cl055 d"1
      1
                         9  10 11
                             Figure 43.  The OCP content decrease
                                         during the respirometric
                                         test.
                              time, days
      The value of the unit oxygen demand  Lu read  out from Fig.  41 amounts to
 -0.085 mg 02/mg OCP.  The mean Lu value,  calculated on the basis of the
 first and the second series, amounted to  -0.08  mg 02/mg OCP which means that
 OCP does not cause any oxygen demand, but it  inhibits the process of oxygen
 uptake for nutrient medium decomposition.  Such inhibiting effect is indi-
 cated not only by the decrease of final BOD of  nutrient medium by the
 presence of OCP, but also by the delay of nutrient medium biodegradation.
 The values  of this lag duration versus initial OCP content are plotted in
 Fig. 42.

      The tests of OCP biodegradation  at low concentrations (5 and 10 mg/l)
 gave the results presented in Fig.  43.  As the  BOD was not recorded  (except
                                       57

-------
of blank sample  BOD),  the  curves  of OCP content decrease are the only results
presented.  The  OCP  concentration found in the soda-lime at the end of the
tests are measurable,  but  it  was  so small  that it could be neglected.  The
slope of the straight  lines on  Fig.  43  indicates the value of  kinetic
coefficient ks to equal  -D-OSd'1  which  can be compared with the value k
determined for BOD process in the blank sample, equal to 0.15 d"1.  Therefore
the ratio r = ks:kn  is equal  to ca.  0.3 in both cases (co = 5 and co = 10 mg/1)
The graph corresponding  to 10 mg/1 (Fig. 43)  shows"also a lag phase, lasting
ca. 2 days which indicates that the OCP biodegradation needs a certain
period for acclimatization.

Discussion

     The obtained results  show  that  OCP is only slightly biodegraded in
respirometric tests.  At its  low  concentrations,  up  to 10 mg/1 OCP, the
decomposition of this  substance was  observed  but the decomposition rate
was low.   At an initial  OCP content  of  10  mg/1, two  days for microorganisms
acclimatization was needed.   At higher  initial concentrations, OCP is
not biodegraded.

     However, even at concentrations up to 350 mg/1,  OCP just slightly
affects the microbiological activity which is expressed by the small
decrease of final BOD of nutrient medium and  a certain delay of the process
beginning.   At an initial OCP content of 600  mg/1, the inhibition of the
BOD process was distinctly marked,  and  at  1200 mg/1  the BOD process was
completely suspended.

Biodegradation in river water

     The tests were carried out with the use  of four parallel operated in-
stallations.   The initial OCP content in each of the installations was,
respectively:  2, 5, 10 and 20  mg/1 OCP.   When the OCP content in any of
the installations had dropped down to zero, the next OCP dose was added to
raise the OCP content to the  former initial value.   The results of OCP
content determinations during these tests  are given  in Fig.  44.
                                           I c, mg/1 OCP
           c, mg/1 OCP
     10
c. mg/l OCP
                                                             time, days
                                          0     -0     20

                                           c, mg/l OCP0
                30     40
                 time, days
                                 time, days
                30     40
                 time, days
Figure 44.  The decomposition of OCP in river  water.
                                     58

-------
     TABLE 13.   KINETIC PARAMETERS OF OCP BIODEGRADATION IN RIVER WATER


Initial OCP
content co
mg/1 OCP
2X
5
10
20
After OCP
addition to
the fresh
river water
t V
days mg/l'h
13 0.02
15 0.07
17 0.17
22 0.10


After
OCP
t
days
0
0
0
0


repeated
addition
V
mg/l-h
0.02
0.10
0.09
0.10


After
OCP
t
days
0
0.5
0
-


subsequent
addition
V
mg/l-h
0.03
0.13
0.09
-


After
OCP
t
days
-
0
0.5
-


subsequent
addition
V
mg/l-h
-
0.09
0.13
-
x At 2 mg/1 OCP the decomposition velocity v was not constant.  The data in
  the table are the maximum v values.
     The values of parameters read out from Fig. 44 are shown in Table 13.
This data led to the conclusion that OCP is biodegraded in the river water
but that a long period of acclimatization is needed.  This period lasted
from 2 to 3 weeks, depending on the initial OCP content.  Most probably
this microbiological adaptation is a sociological, not physiological one,
i.e. that  adaptation consists in a change of the species domination in
the river water in the presence of OCP.  The population of these species
which are able to decompose OCP are growing in number during the acclima-
tization period.  Once the biocenosis is adapted to the OCP presence, the
decomposition of OCP after the repeated OCP addition begins without any
delay.  However, even the adapted biocenosis degradates OCP at a low rate,
equal approximately to 0.1 mg/l'h.  At a low initial content (2 mg/1 OCP),
the velocity of the decomposition is not constant and it is lower than
at the higher concentrations.

Treatability tests

     The tests were carried out^with use of three parallel operated instal-
lations.  The results of OCP determinations in the effluent and the
determinations of overall treatability coefficient KCOD are presented
in Fig. 45.

     The data given in Fig. 45 show that the activated sludge acclima-
tization needed 6 to 12 days, depending on the OCP content in the inflow,
ranging from 5 to 10 mg/1.  In the test in which the non-adapted activated
sludge was fed with wastewater containing 20 mg/1 OCP, the acclimatization
was not reached.

     The overall treatability coefficient K^QQ was the same at 5 mg/1 OCP
as in the control unit.  The adapted activated sludge treated the wastewater
                                     59

-------
0.3


Q2
0.1


0
0.3


0.2
0.1




0.3


.i

0.1

o-
-< — 1
KCOD* 9 *'*"
_____
KCOD in the control unit 20%

KrOD in tne test unit\ \ width ot tne confidence strip /
/
i TsOVo removal
'v r/^-^fev^c
"""---j^ H - Jj80% rempyal unJS ^^
0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40
time, days
KCOD- g'-'-h"1
j 18%
KPQQ in the control unit i remowal
	 i 	 T 	 L jf^
\ *\ \l /
KQQD m the test unit\ \width of tire confidence strip V /
15% remowal, / \
25% ! /I \
1 remowal {/ \
Co I W—2S^ M H J ^\ ^P
^_ _j ),/ "T x w
M MH^ O^V ~^7fl°/ f

32468 10 12 14 16 18 20 2'2 24 26 28 30 3-2 34 36 38 40
time, days
u- -1 i k-1
KCOD • 9 '''n
KQQQ in the control unit 1 f
\ I /
• i
\ !/
width of the confidence strip \ 7\
j \
^2. , 	 _j \
	 _\ J2°_)l LSEfliRL r***~ 39ct^"^W<
X " " T *
c. m^/IOCP
50

40
30
•20
•in


c, mo/I OCR
100


50



c. ma/l OCR
200


150
inn

50

n
        0   2   4   6   8  10 12 14 16 18  20 22  24  26  28  30  32  34  36  3"8  40
                                                            time, days

Figure  45.   Overall treatability and OCP  removal by activated sludge.


                                       60

-------
with the same value of Kcnn at OCP concentrations up to 40 mg/1 (gradually
increased).

     Similarly, the feeding of the activated sludge with wastewater with
10 mg/1 OCP, gradually increased to 40 mg/1, did not affect the overall
treatability.  In the test in which the non-adapted activated sludge was
fed with wastewater containing 20 mg/1 OCP, the value of K^QQ slightly
decreased.  However, it remained at the level of ca. 75 percent of the
value corresponding with the control unit even when OCP content was in-
creased gradually up to 80 mg/1.  OCP at concentrations of 100 mg/1 and
above poisoned the activated sludge and KPQD coefficient decreased down
to a very low value.

     The OCP removal from wastewater containing up to 10 mg/1 OCP proceeds
with quite good efficiency Ks = 0.2 g-i-l-h"1.  With the increase of OCP
content in the inflow, this efficiency decreases and does not depend on
the time of the activated sludge acclimatization.

TRICHLOROPHENOL, TCP

Respirometric Measurements

     Four series of tests were made.  In the first three series, BOD was
recorded and the final TCP content was determined.  The third series con-
sisted in comparative determinations of the process in the samples seeded
with the inoculum alternatively not adapted or previously adapted to the
TCP presence.  The fourth series consisted in the determination of the TCP
content during the test (BOD was not recorded).   As TCP is a somewhat
volatile substance and because of its acidic properties it can be absorbed
by the soda-lime mixture, the determinations of TCP content in the absorbers
were also made similarly as in the tests with OCP.  The results showed that
TCP is much less volatile than OCP.  The soda-lime mixture contained measur-
able quantities of TCP after the tests were completed but these quantities
were small and could be neglected.

     The conditions of the test performance are given in Table 14.


 TABLE 14. CONDITIONS OF RESPIROMETRIC MEASUREMENTS OF TCP BIODEGRADABILITY

           Number ofTestRange of
     No.   samples in   duration,   Nutrient               concentration,
           the series     days       medium      Seed           mg/1
I
II
Ilia
Illb
IV
8
6
3
3
6
18
13
7
7
7
yeast extr. wastewater
ii n n
" " not adapted
" " adapted
" " wastewater
0 - 540
0-20
10
10
12
                                     61

-------
 200-
    BOD, mg/l 02
                                            Lc, mg/l02
                                          170
                                          160
     1 234  56 7 8 9 10 11 12 13 14 15 16 17 18
                               time, days
Figure 46.  BOD curves of nutrient
            medium with various  con-
            centrations of TCP.
Figure 47.  The final carbonaceous
            BOD Lc as a  function of
            initial TCP  content co.
 TABLE 15.  BOD PROCESS  IN  THE  SAMPLE CONTAINING VARIOUS TCP CONCENTRATIONS
Initial TCP
content CQ
mg/1
0
10
20
35
90
210
540
Final TCP
content
mg/1
0
0
0
0
80
190
500
Final carbo-
naceous BOD
mg/1 02
140
145
160
170
140
145
145
NOD
mg/1 02
35
32
30
25
20
10
10
k
of1
0.09
0.09
0.08
0.09
0.09
0.085
0.08
     The exemplary  BOD  curves resulting from the first test  are  presented in
Fig. 46.  The  logarithmic transformation of those data follows  straight lines
lying very close  to one another.   The kinetic parameters read out  from the
logarithmic  curves  are  presented in more readable tabular  form  in  Table 15.
                                      62

-------
     log c
                       £56
                         time, days
                                          BOD, mg/f 02
                                          inoculum adapted
                                            Lc--165 k=0,2
                         5    6
                            time, days
Figure 48.  The TCP content decrease
            at the initial concentra-
            tion 12 mg/1 TCP.
  Figure 49.   The influence of adapta-
              tion on BOD process in
              the samples containing
              10 mg/1 TCP.
     The dependence of the final carbonaceous BOD of the samples containing
nutrient medium and TCP on the initial TCP content CQ  is shown  in Fig.  47.
The points on this graph correspond only with those samples  in  which  TCP
was fully decomposed at the end of the tests. This was confirmed by the final
TCP content analyses.

     The value of unit oxygen demand L  read out from  this graph is equal  to
L  = 0.91 mg 0 /mg TCP.  The similar determination of  LU in  the second  series
gave the result L  = 0.85 mg 02 TCP.  These values are not precise because
they are based onurather low BOD values of samples with small TCP addition
that causes the relative large error.

     The test of TCP decomposition in Sapromat apparatus gave the result
presented in Fig. 48.

     The influence of the seed acclimatization on the  BOD process in  the
presence of 10 mg/1 TCP is shown in Fig. 49.  The curves are for the  seed
alternatively adapted and not adapted.

Discussion

     If it can be assumed that the TCP biodegradation  follows the equation:
          C1-.C,H..OH + 5.5 0_
            3  o 2.           2.
6 CO  + 3 HC1
the stoichiometric value of the unit oxygen uptake would  amount  to  0.89 mg
0?/mg TCP.  The mean value resulting from the  tests  is  equal  to  0.88 mg 0 /mg
TCP which is near to the stoichiometric value.   It should be  stated that
this value is adequate to calculate the final  BOD of the  samples containing
initially 35 mg/1 TCP or less.  At the higher  initial concentration TCP is
not biodegraded and does not cause any oxygen  demand.
                                       63

-------
     The determination  of the kinetic parameters shows that TCP does not
 inhibit the process of  nutrient medium biodegradation.  Even at high TCP
 content of 540 mg/1 no  delay of nutrient medium decomposition was observed.
 Similarly the value of  kn coefficient and the final BOD of nutrient medium
were not decreased by the presence of TCP.

     The TCP decomposition proceeded only at the initial TCP concentration
 up  to 35 mg/1.  Any delay of the TCP decomposition could not be read out
 from the BOD curves.  However, the curve of TCP content decrease  (Fig. 48)
 indicates that TCP decomposition at its initial contents 12 mg/1 needed ca. 5
 days for microorganisms acclimatization.  After that the TCP decomposition
 proceeded at a high rate (k  =0.9 d"-*-) .

     The previous acclimatization of the seed to the TCP presence accelerates
 the BOD process.  This  is indicated by some increase of the coefficient k
 value (Fig. 49).

 Biodegradation Tests in River Water

     Two series of the  tests were made.  In the first series two river models
 were operating in parallel with the initial TCP content 8 and 15 mg/1,
 respectively.  The second series was carried out with use of three river
 models with initial TCP content 5, 8 and 10 mg/1.  In any case, when TCP
 was fully decomposed, the TCP dose was repeated (the tests of microorganisms
 acclimatization to the  TCP presence).

     The results of both series are presented in Fig. 50.  These graphs show,
 that the TCP biodegradation in the river water needs a certain period of
 biocenosis acclimatization (ca. 6 days) during which TCP is decomposed at
 a low rate.  Once the biocenosis is acclimatized, the next dose of TCP is
 biodegraded without any delay (or after short delay) and at a rate of about
 0.35 mg/l-h.  At low initial TCP content (5 mg/1), this rate is somewhat
 lower.

 Treatability Tests

     One test lasting 38 days was carried out.  The activated sludge was fed
 with wastewater with gradually raising the TCP content from 5 mg/1 at the
 test beginning to 25 mg/1 at the end of the test.

     The results of the determinations of the TCP in the effluent c  and of
 the overall treatability coefficient K    are presented graphicallyein Fig. 51,
 On  the basis of these results, the following conclusions can be made.  The
 activated sludge did not need any acclimatization period for its normal
 activity until the TCP  in the inflow surpassed 18 mg/1.  The overall treat-
 ability coefficient K    was stable during the tests and equal the value of
 KCOD corresPondin8 to ™e control unit.  However, when the TCP content in the
 inflow equaled  25 mg/1 it poisoned the activated sludge, and K    dropped to
 zero.                                                        UJU

     The TCP removal from wastewater needs some period of adaptation t7
 depending on the TCP content in the inflow:  at 5 mg/1 TCP t, = 0; at

                                      64

-------
   c. mg/1 TCP
      log  phase 6.5 days
0.20
                                                 v=0.20
  0   42   3   I  5   6   1  8:   9
    c, mg/l TCP
   11  12  13 ft". 1?  1"6
                time, days
                                                            v=0.33
     lag phase 6.5 days
                            7   5   9  10  11   12  13  U  15 1
  0   1   2   3   4   5   6   7   8   9  10  11  12  13  14   15  16
                                                      time, days

   c.  mg/l TCP
                                          11  12  13  U  15 ,
                                                      time. 
-------
       0.3
       0.2-
       0.1
 KCOD. 9 •'•"'
   KQQQ in the control  unit
L\__—
                             width of the confidence  strip
                    in the test unit
                         _t
                     A     A
                                                                  c, mg/l TCP
                                                                  24  T
                                                         20
                                                                  10
        0  2  4  6  8  10  12  14  16 18 20 22  24 26 28 30  32 34 36 38 40
                                                         time, days

Figure 51.  Overall treatability and TCP  removal by  activated  sludge.


10 mg/l TCP t, = 2; at 18 mg/l TCP t  = 5 days.  The adapted activated sludge
removed TCP from wastewater with hign efficiency; the effluent contained just
traces of TCP.  An increase of TCP contents in the inflow up to 35 mg/l
caused a decrease of TCP removal efficiency down to  near zero.

DICHLORODIETHYL ETHER, DCDEE

Respirometric Measurements

     Two series of the tests were  carried out.  Yeast extract  (200 mg/l) was
used as nutrient medium and the samples were  seeded  with the wastewater
previously aerated.  The DCDEE contents ranged from  0 to 500 mg/l  in the
first series and from 0 to 15 mg/l in the second one.

     Exemplary BOD curve from the  first series is presented in the Fig. 52.
All BOD curves obtained in this series were posed very close one to another.
Therefore, to make the graph more  readable Fig.  52 shows only  the  BOD curve
of the sample containing 100 mg/l  DCDEE,  compared with the  BOD curve of
blank sample and the carbonaceous  BOD of  the  blank sample,  corrected on
the basis of N0? and NO, content determinations.

     The values of final carbonaceous BOD were determined for  every BOD curve
and they are plotted versus the initial DCDEE content (Fig. 53).  The slope
of the straight line in Fig. 53 does not  differ  significantly  from zero.
It means that the unit oxygen uptake  caused by DCDEE is  equal  to zero or
too small to be measurable.
                                      66

-------
 uo
  01234567
                      10  11  12 13 14 15 16
                              time, days
                                                     200
                                                          300
                                                                400
               500  .
              C0, mg/l DCDEE
Figure 52.  BOD curve of the sample        Figure  53.
            containing DCDEE.
Final carbonaceous BOD
L  as a function of
initial DCDEE content c
     The values of k  coefficient of nutrient  medium biodegradation ranged
irregularly within tRe narrow  limits 0.15  -  0.17  d-1 in the first series and
0.2 to 0.25 d"1 in the second  series.  The lag phase of nutrient medium bio-
degradation was not observed in any test.

     The final DCDEE content and the N02 and NO  increase during the tests
are given in Table 16.  In the second  series no change of DCDEE content
during the test was observed either.

     TABLE 16.  THE INITIAL AND FINAL  DCDEE  CONTENT AND N02 AND NO
                INCREASE DURING THE TESTS  IN SAPROMAT (THE FIRST SERIES)

Initial
CQ, mg/l
0
14
41
107
205
512
DCDEE
Final
c£J mg/l
0
15
40
109
203
501
N02 + NO
mg/l N
9.5
1.2
0.5
0.3
0.2
0.6
                                      67

-------
           c, mg/l DCDEE
          01  2   3   4   5   6  7

           c, mg/l  DCDEE
                                      9  10  11  12 13  U  15  16  17  18
                                                          time, days
          0  1   23   A   567
                                      9  10  11  12  13  U  15  16  17  18
                                                          time, days
Figure 54.  DCDEE changes in river water.
Discussion

     The unit oxygen uptake caused by DCDEE was measured as equal to zero
(L  = 0).   No lag phase of nutrient  medium decomposition was observed.  The
coefficient k  of nutrient medium decomposition was also not affected by the
DCDEE.  The determination of the final DCDEE content showed that DCDEE is not
degraded during the tests.  Summarizing, it can be concluded on the basis of
these results that DCDEE is an inert substance which is not biodegraded but
does not affect in anyway the biodegradation of the other organics  (yeast
extract components).

     The only effect of DCDEE on the biochemical processes was the  inhibition
of nitrification.  At a DCDEE concentration of 14 mg/l and higher,  the
nitrification was almost completely inhibited; whereas, in the blank sample
almost all the ammonia was converted to NO,, and N0_.
Biodegradation in River Water
                                                                           As
     Two series of tests were made using two units operating in- parallel.
DCDEE is a volatile substance, the river models were sealed to avoid any
DCDEE loses due to evaporation.  In both series the DCDEE content was analyzed
during the tests.  The results are presented in Fig. 54.

     In the second series the NH  and NO  changes were also observed during
the test.  The aim was to determine the influen.ce of DCDEE on the nitrification
of ammonia in river water.  The results are presented in Fig. 55.
                                      68

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                           3 mg/l DCDEE



                            6 mo/1 DCDEE
     0   2  4   6  8  10  12  14   16  18
                             time, days
                                             c, mg/l N-NH3
                                                blank sample
                 3mg/i DCDEE


                   6 m^/l DCDEE




                        =***
0  2 •  4   6   8   10  12 14  16 18
                        time, days
Figure  55.  Nitrites  and  ammonia changes in river water.
Discussion

     The DCDEE  content  curves  show that  this substance is resistant in the
river water.  A small decrease of DCDEE  was observed at the beginning of
tests.  Beyond  this, no further DCDEE  decrease was observed.

     The observation of the  nitrification process leads to the conclusion
that DCDEE at concentrations up to 6 mg/l does not inhibit the nitrification
but causes a delay  of this process (lasting 1.5 to 2 days).

Treatability Tests

     One series  of  test was  carried out  by use of two parallel operating
activated sludge units  fed with the wastewater containing 5 and 10 mg/l
DCDEE, respectively.  As DCDEE is a volatile substance, the supplementary
determination of its Henry coefficient a_ was made.   The air was bubbled
through the DCDEE solution in  distilled~~water.   DCDEE content and the weight
of the solution  were measured  during the test.   The results were plotted in
the logarithmic  coordinates  system (Fig.  56).   The slope of the straight
line was read out,  and  according to the  equation given in Section 6,  the
value of coefficient a_  was calculated  equal to 0.37 x 10~3.  Assuming that
the evaporation  of  DCDEE is  the only cause of its content decrease in the
activated sludge chamber, the  DCDEE content in the effluent would be  equal
to: :
                    c  =
                     e
                          1+a  • —
where v  is the rate of air blowing, equal to 300  1/h and V   is  the  rate of
wastewater inflow, equal to 0.17 1/h.  As the value of a amounts to  0.37 x
10~3, c  should be equal to 0.6 • c  .
       e                           o
                                      69

-------
                 2.00-
                 1.99-
                 1.98
                 1.97
                 1.96
                 1.95
log c
             slope 18.74
                     2.397      2398       2399      2.400
                      log ot the weight of solution
Figure 56.   The volatility of DCDEE  from aqueous solution.
6
5i
i
3
2

1

c, my'l DCDEE
UJ Ol
, iu£ —
\ o i ^
\ / ^ f\ rt
\ ,°l°
\ y
V-A


v^ . i: ^

v*"1 • — i|r
ce i
i
^Bh .!. ^Sh
1
0 i 2



9


8

7

6
5
t.
3
2
1
n
3 i 5 6 7 8 9 10 11 12 13 U 15 16 17 18 19 2'0 21
time, days
c, mo/1 DCDEE

2)
LU °
LLl 01
Q c
0 >
DO
n


V^


V

/\ A
^^ ^^ / ^^r ^V
./ HI, / ^ ^^
v<- v \
                                                              time,  days
Figure 57.   DCDEE concentration in the  effluent from  activated sludge unit.
                                      70

-------
     The results of the determinations of the DCDEE content in the effluent
c  are presented in Fig. 57  on which the theoretical DCDEE content decrease
by the blowing out is also marked.

     The overall treatability coefficients K    were calculated on the basis
of COD determinations.  The obtained values snow just irregular scattering.
The mean values and their confidence limits are as below:

          control unit KCQD = 0.20 ±0.06

          at DCDEE content in the inflow of 5 mg/1, KCQD = 0.20 + 0.07

          at DCDEE content in the inflow of 10 mg/1, KCOD = 0.16 ± 0.09

     The scattering of the results causes rather wide confidence limits.
Because of it, any decrease of K    value in the presence of DCDEE cannot
         i                       (jUJJ
be stated.

     It can be concluded that DCDEE content in wastewater does not affect
significantly the overall treatability of wastewater (i.e. the COD decrease).
Thus, DCDEE is an inert substance in the treatment process.  Its removal
is caused just by the blowing off with the air in the aeration chamber.

FLUORESCENT WHITENING AGENTS, FWAs

Respirometric Measurements

     Two kinds of the tests were carried out.  The tests of the first kind
(BOD tests) consisted in the recording of the BOD of the samples, each
containing nutrient medium and one of the five various FWAs (100 mg/1).
For the inoculum, the activated sludge supernatant was used.  After com-
pleting the tests, lasting 12 days, the final FWAs content was determined.
Next the tests were repeated, similarly as before, except that the solu-
tions remaining from the previous tests were used as inoculum (acclimatization
tests).

     The tests of the second kind consisted in the measurement of the
activated sludge endogenous respiration in the presence of various FWAs.
The procedure was as follows:  the settled activated sludge was put into
the flasks of Sapromat and the FWAs solutions in the dilution water were added.
The activated sludge respiration was recorded during 10 days and compared
with the respiration of the blank sample (the same activated sludge without
any FWA addition).  Every FWA was tested in three identical samples to reach
the higher reliability of the results.  After the tests were finished, the
FWAs content were determined.

     The results of the BOD test for FWA-1 is presented in Fig. 58.  The BOD
curves for the other FWAs are very similar to that shown in Fig. 58, e.g.,
the blank sample and the sample with 100 mg/1 FWA have identical oxygen
uptake.  Figs. 59 and 60 present exemplary curves of the activated sludge
endogenous respiration in the presence of FWA-1 and FWA-3.


                                      71

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                           inoculum: supernatant of the
                              activated sludge
inoculum: the liquid
 ot test I
                      123456789  10 11  12 1  2 3  I 5  £>
                                                          time, days
Figure  58.   BOD curves of the samples  containing  nutrient medium and  100 mg/1
             of  FWA-1.
               1200
                1000
                 800
                 600
                 400
                 200
Figure 59.  The curve of  activated  sludge endogenous respiration  in the
             presence of FWA-1.
                                         72

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     1500-
     1000
      500
                                                            BOD, mg/f 02
                            8    100
                            time, days
         6    8    10 0
             time, days
                      4     6
                    time, days
Figure 60.  The curves of activated sludge endogenous respiration in the

            presence of FWA-3.
           TABLE 17.  THE  FINAL FWAs CONCENTRATIONS IN THE SAMPLES
                      CONTAINING INITIALLY ONE OF THE FIVE FWAs
                       (100 mg/1).   (THE TESTS LASTED 10  DAYS.)
              Final  FWA      FWA-1   FWA-2   FWA-3   FWA-4   FWA-5

            concentration	

                mg/1           5
21
91
69
                        87
     The results  of final FWAs content determination are summarized in Table
 17  (BOD tests)  and in Table 18 (activated sludge respiration tests).   The
 last table  contains also the data of final BOD  (mean values  and the limits

 at  90 percent  confidence).
                                        73

-------
       TABLE 18.  BOD AND FINAL FWA CONTENT IN THE SAMPLES CONTAINING
                  CA. 2 g/1 OF ACTIVATED SLUDGE AND ONE OF THE FWAs.
Initial
FWA concentration
mg/1
FWA-1


FWA- 2



FWA- 3




FWA-4


FWA-5

0
100
0
100
180
300
0
20
0
100
0
200
0
20
100
0
20
100
Final BODio
concentration
mg/1 mg/1 0?
0
5
0
10
15
30
0
4
0
70
0
180
0
15
70
0
10
100
1125
1170
1500
1520
1610
1780
1450
1400
1130
1080
900
680
920
925
1060
1530
1550
1440
± 130
+ 90
± 140
± 110
± 100
± 180


± 120
± 100
± 80
± 30
± 150
± 110
± 190
± 180
± 120
± 80
Discussion

     The BOD curves of the samples containing nutrient medium and FWAs
additions show that the FWAs do   not affect the BOD process.  It means
that the FWAs are not subject to very much decomposition, which would
cause the oxygen uptake, and that  they do not inhibit the process of.
nutrient medium biodegradation.  Acclimatization of microorganisms to the
FWAs presence does not change the BOD processes.

     The similar conclusion can be made on the basis of the activated
sludge respiration data.  The oxygen uptake by activated sludge endogenous
respiration in the FWAs presence was almost the same as in the blank sample
                                      74

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(the differences were statistically not significant).   One exception was the
FWA-3 at 200 mg/1 which inhibited the respiration of activated sludge.

     The data of final FWAs contents show that FWA-1 and FWA-2 are not resistant
at the conditions of the tests (i.e. in the samples aerated and kept in
darkness).   The final FWA-4 content was not much lower than its initial
content.   The FWA-3 and FWA-5 were almost resistant in the solutions with
their high initial contents.  But in the case of FWA-3 at the low initial
content equal to 20 mg/1, it decreased to a low value.  It may be caused by
the FWA-3 adsorption on the activated sludge floes because this FWA is easily
adsorbed as it was confirmed in the experiments described further.

     It should be underlined that the above described partial FWAs decomposi-
tion was based on fluorimetric analyses.  The FWAs concentrations were deter-
mined based on the fluorescent properties of FWAs molecules.  Such results do
not mean that the FWAs are really degraded.  The FWAs molecules could lose
their fluorescent properties as a result of a simple transfiguration  (e.g.,
cis-trans)  or as a result of their breaking into large fragments  (e.g., by
the oxidation and breaking of the double bond of styrene structure).  As no
measurable oxygen uptake was observed in the samples in which FWAs content
decreased,  it can be concluded that no large amount of degradation occurred.

The Decomposition in River Water

     Two kinds of tests were made.  The tests of the first kind consisted in
the long term observation of the FWAs content  changes in river water kept
in darkness.  In parallel, FWAs in distilled water, kept at the same  condi-
tions, were also observed.

     In the tests of the second kind, the river water with FWAs was exposed
to the light of fluorescent tubes at an intensity of 1000 lux.  Also in these
tests, FWAs solutions in the distilled water, exposed to the light, were used
as the blank samples.  In the last case, the total organic carbon  (TOC) was
also measured.  Additionally, the river water models and blank samples were
kept in the darkness to compare the FWAs decomposition in the presence and
in the absence of the light.

     As the rate of the FWAs photolytic decomposition depends on pH, phosphate
buffer solution was always added to the blank samples (FWAs solutions in the
distilled water) to keep pH at the same level as pH of river water used in
the tests (8 - 8.5) .

     The results of 30 days testing of the FWAs fate in the river water in the
absence of the light showed that FWAs at these conditions are almost resistant.
The FWAs contents decreased just a little, 10 to 20 percent of the initial
value (10 mg/1).  Even this small decrease probably was not related to the
biodegradability because in the blank samples, which were almost microbiolog-
ically sterile, some FWAs decrease was observed.

     The decomposition of FWAs exposed to light proceeded at a high rate so
that FWAs content had to be measured every half hour.   In the samples
                                       75

-------
     c,,mg/ FWA-1
               = 11 mg/l-h
 10
   0   1
234567
            time,  days
                                   c, mg/l FWA-2
                                                   v=13 mg/l-h
                                                      distilled  water
                                            0   1
5   6   7
 time, days
Figure 61.  Photolytic FWA-1 decom-
            position in river and
            distilled water.
                               Figure 62.  Photolytic FWA-2  decom-
                                           position in river and
                                           distilled water.
 50
 30-
 20-
    c, mg/l FWA-3
          v = 5 mg/l-h
                v = 5 mg/l-h
                 river water
      distilled water
             v=1.5 mg/l-h
   0   1    23456.7
                     time, days
                                                  Figure  63.
                                                   Photolytic  FWA-3
                                                   decomposition  in
                                                   river and dis-
                                                   tilled water.
                                      76

-------
    c, mg/ FWA-4

       distilled  water
              river water

                  v=3.6 mg/l-h
50Jc.mg/FWA-5
                     5   6   7
                     time, days
           river water

            v=7 mg/l-h

                distilled water
  0
                        time, days
Figure 64.   Photolytic FWA-4  decom-
            position in river and
            distilled water.
 Figure 65.  Photolytic FWA-5 decom-
            position in river and
            distilled water.
   TABLE 19.   VELOCITY v OF  THE  FWAs  DECOMPOSITION IN RIVER AND DISTILLED
              WATER EXPOSED  TO LIGHT
Velocity of FWAs decomposition,
FWA
In river water at
initial FWA content


FWA-1
FWA- 2
FWA- 3
FWA-4
FWA-5
c = 10
o
5
9
1.5
2
5
c = 50
o
6
13
5
4
7
mg/l'h.
In distilled water at
initial FWA content
c = 10
o
7
.14
5
8
11
c = 50
o
11
13
5
9
12
                                     77

-------
simultaneously kept in darkness no FWAs change was observed.  The curves of
FWAs decomposition are presented in Figs.  61, 62, 63, 64 and 65.

     The curves show the decrease of FWA down to the residual value c  related
most probably to the fluorescence of the FWA decomposition product.

     During the initial period of FWAs photolysis, the decomposition velocity
is usually constant.  The values of decomposition velocity v, being equal to
the slope of the initial section of lines, are read out from the graphs and
are shown in Table 19.

     The additional TOG determinations in the samples of FWAs in distilled
water show that the FWAs decomposition is not related to any TOC decrease.
Final TOC values were almost the same as the initial values, whereas the FWAs
content dropped down to the residual values  c^.

Discussion

     The long term tests of the FWAs fate in the river water in the absence
of light have shown that all FWAs tested are resistant.  No FWAs biodegrada-
tion was observed during 30 days.  The observed small FWAs decrease, equal
to 10 to 20 percent of the initial FWAs concentrations, is probably due to
physical processes.

     The tests of FWAs decomposition in the presence of the light have shown
that all FWAs tested are subject to the photolytic decomposition.  According
to the tests with FWAs solutions in distilled water, the most easily decom-
posed FWAs are FWA-2 and FWA-5, whereas FWA-3 is the most difficult to decom-
pose with a rate less than one half of the FWA-2 or FWA-5 decomposition rate.

     The decomposition rate is initially almost not dependent on the FWAs
concentration and next it is decreasing asymptotically to zero.  The FWAs
solutions after a long time of exposition to the light (1 days or more)
retain a residual fluorescence, corresponding with 5 to 10 percent of their
initial value.

     The decomposition of FWAs in river water proceeded similarly as in the
distilled water.  At the initial FWAs concentration of 50 mg/1, the
decomposition rate in river water was equal to or less than in the distilled
water.  At the concentration of 10 mg/1, the FWAs were decomposed in river
water at significantly lower rates.  The fact that the decomposition of FWAs
is slower in the river water than in the distilled water can be explained
as a result of the light extinction in the river water because of colored
impurities.  This absorption of the light decreases the amount of light needed
for photochemical reaction of FWAs decomposition.

     The fact that the solutions keep the residual fluorescence and that the
TOC is not changed during the tests, leads to the conclusion that chemical
changes of FWAs molecules were very little.  It could be a cis-trans trans-
figuration or division to large fragments.
                                      78

-------
            TABLE 20.  THE ADSORPTION OF FWAs ON ACTIVATED SLUDGE
                         c       c        m       a       b
                          o       e

               "^*r^     ~     ~~
                         10     4.86

               FWA-2      5     3.52

                teSt X   10     7.96
                                                 3.1     5.6
                test 2    5     3.45     _
                                         / • 3
                         10     8.26

               FWA-3      5     1.5      , ,
                «Stl   10     5.1       '6
                                                 1.0      1.0
                test 2    5     0.9
                                         / • O
                         10     3.75

               FWA-4      ^     ^7?
               hWA 4      b    •  '/Z     4.8     1.3     9.2
                         10     8.03

               FWA-5      5     5
                                         7.3
                         10    10
Treatability Tests

     As the adsorption of FWAs on the floes of activated sludge  can  interfere
with the FWAs biodegradation determinations, supplementary tests of  FWAs
adsorption were carried out.  The procedure was as follows:   into the  sample
of the settled activated sludge of a known density (dry mass)  the FWAs stock
solution was added and after 1 hour of FWA contact with the activated  sludge
the FWA content in the supernatant was determined.  Next,  the coefficients
of the Langmuire's isotherm of adsorption were calculated,  following the
equation:

               c  - c      c        ,
                o    e _    e    , where:
                  m      a«c +b
                            e

     CQ  is the initial FWA content in the supernatant,  mg/1

     cg  is the FWA content in the supernatant at  the  state  of equilibrium
         with the adsorbed FWA,  mg/1

     m  is the dry mass of the activated  sludge, g/1

     a_ and b_ are Langumire's coefficients.

The results are summarized in Table 20.

                                      79

-------
     The tests of the FWAs treatability were carried out with the use of three
parallel operated activated sludge units as follows:

          - test unit, fed with wastewater containing the FWA addition

          - control unit I, fed with wastewater without any FWA addition

          - control unit II, fed with distilled water with FWA addition.

     The measured parameters were:

          - FWAs content in the inflow c  and in the effluent c
                                        o                      e
          - COD in the inflow and in the effluent

          - activated sludge dry mass m in the test unit and control unit I.

     On the basis of the obtained data, the following treatability coeffici-
ents were calculated.  The general FWAs removal coefficient K was determined
by use of the equation

                        c  - c
                    K=
                         c mt
                          e  r

where tris the retention time.  It can be assumed that the general coefficient
K is the sum of the coefficient K,  of FWA removal by degradation, the coef-
ficient Kph of FWA removal by photolysis and the coefficient Kad °f FWA removal
by adsorption on the sludge.  The values Kp^ were determined by use of the
equation


                  v   - ACH  •  1
                   ph    c     mt


where Ac   is the FWA decrease in the test unit II; c , m and t^. are corres-
ponding with the test unit.  The values of K   were calculated on the basis
of formerly determined Langumire's coefficients:
                     ad   9   a-c +b
                                 e
where 9 is the sludge age equal to 120 hours, a_ and b are Langumire's
coefficients  (Table 20) , c@ is FWA content in the effluent from the
test unit.  The values  of the coefficient of FWAs removal by the biodegrada
tion are equal toK, =K-K,-K,.
                                      80

-------
     The overall treatability coefficient K
equation
                                               was calculated by use of the
                    K
                     COD
COD  - COD
   o	e_
    COD,,
                                         mt
In cases when the tests were made at high FWAs concentrations in the inflow,
the Kmn values were corrected by substracting the value of COD corresponding
with FWA content both from the measured COD of the inflow and of the efflu-
ent.  This corrected value is denoted as K'  .
                                          L/UJJ

     The results of subsequent FWAs tests are presented in Tables 21, 22, 23,
24 and 25.  In the case of FWA-1, the photolysis significantly decreased FWA
content in the effluent; the general coefficient of FWA removal was approxi-
mately twice the value of K .  In the case of FWA-2, the photolysis caused
a small decrease of FWA content.  Practically, it was the only cause of FWA
removal .

                    TABLE 21.  THE TREATABILITY OF -FWA-1

Test
duration


days
20
27


FWA-1 in FWA-1 in
the inflow the effluent


CQ mg/1 cg mg/1
9.9 1.6
40.0 8.0
TABLE 22. THE
FWA-1
Overall treatability
biodegradation coefficients
coefficient


g~i LIT1
0.08
0.10
TREATABILITY OF
V
b test unit
K'
COD
g-1 i-h-1
0.17
0.17
FWA-2
control
unit K
COD
-1 . . -1
g . 1-h
0.17
0.17

  Test     FWA-2 in     FWA-2 in
duration  the inflow  the effluent
                                         FWA-2
                                      biodegradation
                                      coefficient K,
                            Overall treatability
                                coefficients
                            test unit   control
                              KCOD     Unit KCOD
days
10
18
24
34
40
CQ mg/1
6
10
45
100
200
cg mg/1
4.9
10.1
44.3
~ 100
~ 200
g-1. Lh-1
~ 0
~ 0
- o
~ 0
- o
-1 - , -1
g • 1-h
0.18
0.19
0.18
0.14
0.13
-1 . , -1
g • 1-h
0.17
0.18
0.19
0.17
0.18
                                     81

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TABLE 23.  THE TREATABILITY OF FWA-3
Test
duration
days
5
11
18
24
32
FWA-3 in
the inflow
CQ mg/1
5
10
16
24
80
FWA-3 in
the effluent
ce mg/1
3.0
6.2
8.1
18.0
64.5
TABLE 24. THE
Test
duration
days
11
16
FWA-4 in
the inflow
c mg/1
4
44
FWA-4 in
the effluent
cg mg/1
4.3
44.4
TABLE 25. THE
Test
duration
days
11
16
FWA-5 in
the inflow
C0 mg/1
4
40
FWA-5 in
the effluent
ce mg/1
4.2
39.5
FWA-3
biodegradation
coefficient K,
b
-1 . , -1
g ' 1-h
0.029
0.021
0.042
0.012
0.008
Overall treatability
coefficients
test unit control
KCOD Unlt KCOD
-1 , , -1 -1 . , -1
g • l.h g • 1-h
0.18 0.17
0.15 0.19
0.14 0.19
0.06 0.18
0.05 0.18
TREATABILITY OF FWA-4
FWA-4
biodegradation
coefficient K,
b
g~* 1-h"1
~ 0
~ 0
Overall treatability
coefficients
test unit control
KCOD Unit KCOD
g"1 1-h"1 g-1 1-h"1
0.16 0.16
0.15 0.15
TREATABILITY OF FWA-5
FWA-5
biodegradation
coefficient K,
-1 . , -1
g • 1-h
~ 0
~ 0
Overall treatability
coefficients
test unit control
KCOD Unit KCOD
-1 . , -1 -1. , -1
g • 1-h g • 1-h
0.16 0.16
0.16 0.15
                  82

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Discussion

     The obtained results show that FWA-2, FWA-4 and FWA-5 are not biodegraded
in the activated sludge process.  The highest removal rate was observed in the
case of FWA-1 but even in this case the treatability coefficient K is rather
low being equal to ca. 0.1 g-*1 1-h'1.  FWA-3 is less biodegradable than FWA-1;
its Kb value is equal to ca. 0.03 g-^l-h'1 and it decreases down to 0.01
when FWA-3 content in the inflow increases above 20 mg/1.

     The overall treatability of wastewater is not affected significantly by
any of FWAs in the inflow, except FWA-3 which decreases the KCOD value when
its content in the inflow surpasses ca. 20 mg/1.  Certain decrease of K^
was observed also in the case of FWA-2 at its high content in the inflow
(100 mg/1 and above).
                                       83

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                                  SECTION 8

                          THE RESULTS OF BIOASSAYS
METHYLETHYL KETONE, MEK

     Behavior.   The test organisms  (fish, Lebistes reticulatus) reacted
with darkening when they were exposed to MEK at the concentration of 2000 mg/1.
At 2600 mg/1 MEK, the disturbing of the balance was observed.  At 3400 mg/1
MEK, the fish were laying flat on the vessel bottom.  At MEK concentrations
near LC5Q, i.e. 5000 mg/1, the fish were paralysed.

     The mortality of fish at various MEK concentrations is shown in Fig. 66.
LC50~24 h Was found as equal to 5700 mg/1 MEK.

     The results of a supplementary test with algae Chlorella sp. are given
in Table 26.
               100
                                           8    .  10
                                            c, g/l MEK
Figure 66.  The mortality of fish at various MEK concentrations,
                                     84

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    TABLE 26.   CHLOROPHYLL "a" CONTENT  IN THE CULTURE OF CHLORELLA AFTER
   	7 DAYS OF EXPOSURE TO THE PRESENCE OF MEK	

             Test    MEK content,    Chlorophyll "a" content, mg/1
              no*       mg>/1         blank culture    test culture

               1        806             435             487

               2        806             640             660
     The differences in the chlorophyll content in the test samples and
blank samples are within the range of analytical error.  Therefore, any
impact of MEK on the assimilation activity of Chlorella cannot be stated.

DIMETHYL AMINE, DMA

     Behavior.  After 20 rain of exposure to the DMA at 64 mg/1, the fish
reacted with fluttering movements.  At 73 mg/1 DMA the fish turn pale and
their balance was disturbed (partial paralysis).

     The mortalities of fish at various concentrations of DMA are presented
in Table 27.  From the results of the test (Table 27) the approximate value
of LC,-n- 24 h was calculated as equal to 55 mg/1.
     O \J

              TABLE 27.  THE MORTALITY OF Lebistes retlculatus
N. Time
Concen- N.
tration
mg/1
Blank
41.6
54.6
72.8
97.5
130.0
10
\
mm
0
20
20
20
30
20
30

min
0
20
20
20
40
60
1

h
0
20
20
40
60
100
3

h
0
20
20
60
100
100
24

h
0
20
30
100
100
100
                                      85

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    TABLE 28.  CHLOROPHYLL "a" CONTENT IN THE CULTURE OF CHLORELLA AFTER
               7 DAYS OF EXPOSURE TO DMA

               Test    DMA content,    Chlorophyll "a" content, mg/1
no.
1
2
3
4
5
6
mg/i
20
20
40
40
60
60
blank culture
34
40
34
40
57
59
test culture
44
44
48
41
54
56

     The test with algae Chlorella sp. indicates that DMA does not affect the
assimilation activity of these algae.  It is visible from the data presented
in Table 28.

DIMETHYL FORMAMIDE, DMF

     Behavior.   The fish reacted with their balance being disturbed within
the first hour of exposure to 650 mg/1 DMF.  After 24 hours, fish turned
dark.  At 750 mg/1 DMF, the lateral or ventral bend of the fish body was
observed.  The 870 mg/1 DMF caused fluttering movements of the fish.

     The mortality data are presented in Fig. 67.   The value of LC  - 24 h
was found to be 1300 mg/1.                                        50

     Supplementary test with algae Chlorella did not indicate any affect of
DMF on the assimilation activity of Chlorella.  The results of this test
are given in Table 29.

PARA-NITROPHENOL, PNP

     Behavior.  At the lower PNP concentration the reaction of fish was not
significant.  At 18 mg/1 PNP the animals moved slowly at the botiom and
after 30 min they turned somewhat pale and the first symptoms of partial
paralysis were observed.  At the concentration of 32 mg/1, after 20 minutes
the fish turned on their side (they looked almost not alive except for the
weak action of heart and sporadic movements of the fin).  After 2 or 3 hours
all organisms were dead and dropped to the bottom.  The mortality of fish
at various PNP concentrations is marked on Fig. 68.  The LC _- 96 h was
found as equal to 19 mg/1.
                                      86

-------
         100
          60
         o
         S
         E
          20
                           1000
1500
 c,  m
                                                    DM
Figure 67.  The mortality of fish at various DMF concentrations.
   TABLE 29.  THE CHLOROPHYLL "a" CONTENT IN THE CULTURE OF CHLORELLA AFTER
              7 DAYS OF EXPOSURE TO DMF
Test
no.
1
2
3
4
DMF content,
mg/1
945
945
1890
1890
Chlorophyll "a"
blank culture
57
40
34
57
content, mg/1
test culture
46
46
43
50
 ORTHO-CHLOROPHENOL, OCP

      Behavior.  Within the first 10 minutes in all solutions tested, the
 movements of fish were rapid and violent.  At lower concentrations the fish
 were acclimated to OCP presence after one hour and their behavior became the
 same as in the control flask.  At the concentration of 15 mg/1 and higher
 most of the fish were paralysed after one hour.  The others got together at
 the bottom.  At the highest concentration and after one or two hours, the
                                       87

-------
                   100
                    80-
                 ^60
                  o
                  o
                  E
                    40-
                   20
                       12  U  16  18  20 22 24  26  28 30  32
                                               c, mg/l PNP
Figure 68.  The mortality of fish at various  PNP  concentrations.
                   100
                    80

                  £

                  £60
                  ~B
                  o
                  E^O


                    20
                            10
12
U
  16     18
c, mgj/l OCR
Figure 69.  The mortality of  fish  at  various OCP concentrations.
fish were almost completely paralysed.   Several of them were alive in this
state during one day.

     Mortality of the  fish at various  OCP concentrations is plotted in Fig.
69.  The calculated LC   - 96 h  was  12  mg/1.
                                      88

-------
            100



             80-

           £
           ^60

           "5
           -*-
           t_
           £40



             20
                                                      7    ,  8
                                                     c, mg/l TCP
Figure 70.  The mortality of fish at various  TCP concentrations.
TRICHLOROPHENOL, TCP

     Behavior.  Four or five minutes after the fish were placed in the test
flasks the solutions in the flasks became turbid.  After the next 5 or 10
minutes the animals began to move rapidly; later on their movements became
slower and the fish kept themselves near the surface.  After 30 to 40 minutes
from the beginning of the experiment, a fine precipitate, causing turbidity,
settled so that the solution became clear.  This precipitate, agglomerated
with fish slime, was visible on the mouths, gill covers and fins of the fish.
At the concentrations above 4.9 mg/l most of the fish were paralysed.
     Mortality of fish in the presence of TCP is shown in Fig. 70.
interpolated LC „- 96 h value was 4.5 mg/l.
                           The
DICHLORODIETHYL ETHER, DCDEE

     Behavior.  After 20 to 30 minutes the animals turned slightly dark and
their colors became more grayish.  At lower concentrations, the fish got
together at the surface, moving slowly.  At higher concentrations the
symptoms of paralysis were visible after 1.5 hours:  the fish kept abnormal
positions.  The dead animals floated at the surface.
     Mortality is presented in Fig. 71.
equals 190 mg/l.
The
calculated LC  - 96 h value
                                       89

-------
             100
              80
            tf-
            >;,
             o
             e
              20-
                  100
200             300
        c, mg/l DCDEE
 Figure  71.   The mortality of fish at  various  DCDEE  concentrations.
 FLUORESCENT WHITENING  AGENTS,  FWAs

 FWA-1

     Behavior.   During the  first period  of  the  test  the  fish  reacted  to  the
 FWA-1 presence  with rapid movements.  After several  minutes the  fish  were
 posed on  the bottom of the  vessel rapidly moving with  their chest  fins.  In
 the  test  media  with the highest FWA-1 content  (21  -  37 mg/l),  the  fish were
 floating,  turned with  their backs down,  and almost did not react when
 touched.   At FWA-1  content  of  15.5 mg/l  the fish were  partially  paralysed.

     The  mortality  of  fish  is  presented  in  Fig. 72.  LC   - 96  h  was equal
 to 16 mg/l.   The determination of LC „-  24  h to Daphnia  magna  gave the
 result of 23 mg/l.                  bu

 FWA-2

     Behavior.   At  the lower FWA-2 content  (below  1  g/1)  the  fish  were
 animated  during the first minutes of the test, and then  they moved more
 slowly.   After  24 hours of  the test, the behavior  and  the look of  the
fish were normal.  At the highest tested  concentration  (above  3 g/1),
 paralysis  and death of fish were observed.   Extravasations were  visible
 on various  parts of the fish body.
     The mortality of fish  is presented in Fig. 73.
 Lebistes reticulatus was  equal  to 1760 mg/l.
 for Daphnia magna was found to be 3900 mg/l.
                   LC  - 96 h for
             The LC5Q- 24 h of FWA-2
                                     90

-------
                     100
                      80
                      40
                      20-
                              10      20     30  ,   40
                                          c, mg/l FWA-1
Figure 72.  The mortality o£ fish at various FWA-1 concentrations.
                     100
                       0       1       2       3,4
                                                 c, g/l FW*-2


Figure 73.  The mortality of fish at various FWA-2 concentrations.



FWA-5


     Behavior.  During the initial three days of the test, in the solutions
with ca.  100 mg/1 FWA-3, the fish were sluggish but reacted when touched.

During the fourth day, the same symptom was visible in the fish exposed
                                      91

-------
                                       80  .   100    120
                                      c, mg/l  FWA-3
Figure 74.  The mortality of fish at various FWA-3 concentrations.


to 89 mg/l FWA-3.  At the FWA-3 concentration of 120 mg/l, little extra-
vasations on the fish body were visible.

     The mortality of fish is presented in Fig. 74.  The LC5Q- 96 h of
Lebistes reticulatus was equal to 110 mg/l.  The LC50- 24 h of Daphnia
magna surpassed the solubility of FWA-3 in water.   At the saturated FWA-3
solution, the mortality of Daphnia magna amounted to 20 percent..

FWA-4

     Behavior.  At FWA-4 content of 4 to 10 g/1, the fish were paralysed
and the extravasations were visible near the gills of the fish.  The backs
of the dead fish were bent near the caudal fins.

     The mortality of the fish is presented in Fig. 75.  The LC50- 96 h
of Lebistes reticulatus was 3000 mg/l.   The LC50-  24 h to Daphnia magna
equaled 9400 mg/l.

FWA-5

     Behavior.  At the lower FWA-5 concentration (4.5 g/1) the fish were
sluggish but reacted when touched.  After several  hours their behavior
was quite normal.  At the higher FWA-5  concentration (6-7 g/1), the
fish were paralysed and extravasations  were visible.   The skin of the dead
fish was chapped.
                                      92

-------
                100
Figure 75.  The mortality of fish at various FWA-4 concentrations
                               5      6   , 7
                                    c. mg/l FWA-5


Figure 76.  The mortality of fish at various  FWA-5 concentrations.



     The mortality of fish is presented in Fig.  76.   The LC  „-  96 h of
Lebistes reticulatus was 6400 mg/l.   The LC  -  24 h of Daphnia  magna was
5600 mg/l.                                 bu            	
                                   93

-------
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                                     99

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                                  TECHNICAL REPORT DATA
                           (Please read Instructions on the reverse before completing)
  REPORT NO.
  EPA-600/2-79-163
                                                          3. RECIPIENT'S ACCESSION NO.
4. TITLE AND SUBTITLE
  INVESTIGATIONS  OF  BIODEGRADABILITY AND TOXICITY  OF
  ORGANIC COMPOUNDS
             5. REPORT DATE
              December  1979
  (Issuing Date)
             6. PERFORMING ORGANIZATION CODE
 . AUTHOR(S)
                                                          8. PERFORMING ORGANIZATION REPORT NO.
  Jan R. Dojlido
9. PERFORMING ORGANIZATION NAME AND ADDRESS
  Institute  of Meteorology and Water Management
  Department  of Water Chemistry and Biology
  01-673 Warsaw ul.  Podlesna 61
  Poland
             10. PROGRAM ELEMENT NO.

              PL-480
             11. CONTRACT/GRANT NO.

              PR-05-532-15
12. SPONSORING AGENCY NAME AND ADDRESS
  Municipal Environmental Research Laboratory--Cin.,OH
  Office of Research and Development
  U.S. Environmental Protection Agency
  Cincinnati,  Ohio 45268
             13. TYPE OF REPORT AND PERIOD COVERED
              Final  1975  -  1979	
             14. SPONSORING AGENCY CODE
              EPA/600/14
15. SUPPLEMENTARY NOTES
  Project  Officer:   Robert L. Bunch   (513)684-7655
16. ABSTRACT
       The development of elaborate  industrial societies has  led  to  proliferation of a
  vast number of complex chemicals for industrial, agricultural and  domestic use.  Some
  portion of these compounds  eventually find their way into municipal  and industrial
  wastewater.  Unless specifically removed by waste treatment processes,  they ultimate-
  ly appear in receiving waters  and  water supplies, thus no longer is  it  sufficient to
  remove biochemical oxygen demand to protect the oxygen resource of the  receiving
  water but individual organic  compounds become a concern.
       Knowledge of the toxicity and biodegradability of organic  compounds will aid in
  designing wastewater treatment processes and be useful in elaborating the criteria foi
  safe concentrations of organics in wastewaters discharged to surface waters7
       This report describes  the testing of twelve compounds both for  biodegradability
  and toxicity.  The compounds  tested were:  methylethyl ketone,  dimethyl amine, di-
  methyl foramide, p-nitrophenol, o-chlorophenol, trichlorophenol, 2,2'dichlorodiethyl
  ether and five flourescent  whitening agents used as components  of  household detergents
  The biodegradation tests performed were respirometric measurements,  river model and
  activated sludge model.  Additionally, for some compounds supplementary tests were
  made for evaluation of their  volatility, photolysis and adsorption on activated sludge
  The toxicity was measured with use of fish Lebistes reticulatus §  crustacean Daphnia
  mnanx	                       	
17.
                               KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                                             b.lDENTIFIERS/OPEN ENDED TERMS
                             COS AT I Field/Group
    Water  pollution
    Biodeterioration
    Organic wastes
    Toxicology
    Sewage treatment
    Industrial waste treatment
 Biodegradability
 Activated sludge
  17C
  13B
18. DISTRIBUTION STATEMENT
   Release to Public
19. SECURITY CLASS (ThisReport)
 Unclassified
21. NO. OF PAGES

  116
20. SECURITY CLASS (Thispage)
 Unclassified
                                                                        22. PRICE
EPA Form 2220-1 (9-73)
                                            100
                                                                  I U.S. GOVERNMENT PRINTING OFFICE: 1980 -657-146/5557

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