United States         Office of
              Environmental Protection    Research and Development
              Agency           Washington DC 20460


              February 1, 1983       EPA 600/9-83-002
&EPA      Research
              Outlook
              1983

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RESEARCH
OUTLOOK
     1983

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RESEARCH OUTLOOK 1983
Contents:



                  1    Introduction



Chapter 1:        7    Hazardous Wastes



Chapter 2:       23    Water Quality



Chapter 3:       45    Drinking Water



Chapter 4:       63    Toxic Substances and Pesticides



Chapter 5:       81    Air



Chapter 6:      101    Acidic Deposition



Chapter 7:      115    Energy



Chapter 8:      129    Exploratory Research



Appendix A:     137    Resource Options



Appendix B:     147    Technical Reviewers

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INTRODUCTION

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INTRODUCTION

     Research Outlook 1983 is the eighth in this series
of reports to  Congress as required by  Section  5 of
Public Law 94-475,  90 Stat.  2071.   It  describes the
major  research  issues,  trends and  strategies of EPA's
research program for the next half decade.

     The primary purpose of EPA's research effort  is
to  support   environmental  program   officials   and
regulatory decision makers  by both responding to  their
near-term  needs   for   scientific   and   technical
information and  by anticipating  future  information
needs  and initiating research  efforts to satisfy  those
needs.

     This edition  of the Research Outlook continues —
and makes more emphatic  — the  issue orientation of
EPA's  research strategy.   As  with  any  long-range
strategy document,  this report is  presented in broad,
summary  terms.  The context within which this is done
is a  discussion  of  approximately  60 of  the  most
important issues being addressed by EPA research.
     Such an  issue  orientation is  intended  to achieve
two things.  First, it overlays a framework within which
the reader  can  understand the  relationships among
EPA's  many different regulatory  responsibilities and
associated research efforts. Without such a framework,
EPA's  2,000 active  research projects would present a
daunting challenge to even the most determined reader.
Second,  the  issue orientation gives our  reviewers a
"handle" by which to grasp and  examine  our overall
research strategy.  The issues we select, along with our
research approach,  are clearly presented  to stimulate
critical discussion.

     The research process, by expanding the horizons
of our knowledge, can raise as  many  questions  as  it
answers.  The  same  is true of this report. For example,
have we chosen the  correct set of issues to  address? Is
our understanding of  the  status and context of  these
issues  adequate?  Do we correctly identify the crucial
information gaps  or bottlenecks to  progress?  Is our
strategy  with  regard  to  providing  the   scientific
information needed to fill these gaps cost-effective?

     Prior to publication,  the chapters in this report
were  reviewed  by more than  100 scientists, research
managers and  environmental regulatory officials within
EPA, other federal agencies, academia, private industry
and public  interest  groups.   They  asked  the above

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questions and   more,  and  their  critiques  not  only
influenced the  content of this  report but also, in the
long run, the content of EPA's research  program itself.
In this sense, the Research Outlook is the first step in
the research planning process.  This report provides the
outline.  The details are filled in by the annual planning
cycle  followed  by  the  detailed  description   and
implementation of the research projects.

      Because of its  summary nature, this report may
leave the reader desirous of greater detail or project-
level information.  Other research summary documents,
which focus on  a shorter time horizon and contain a far
greater level of detail, will soon be made available.

Report Organization

      This edition  of  the Research Outlook  is divided
into  eight  chapters  and two appendices.   The  first
appendix  contains  three  resource   scenarios   and
associated  research  activities.  The second lists the
technical reviewers who critiqued  earlier drafts of this
report.

      Each  of the  eight chapters generally  consists of
the following:

      Introduction:     Defines   the area  of  research
covered in the chapter.

      Legislative Mandate:     Lists  the  laws   which
mandate EPA involvement in general, and research in
particular, with regard to subject of the  chapter.

      Background:  Gives some history and context for
the  overall  discussion. Introduces  EPA's objectives and
the major areas of  focus for the issues that follow.

      Major Research Issues:    Each  chapter contains
discussions  of  from five to  twelve issues.   The issues
are  selected using  one simple criterion  — what are the
key scientific and technical information gaps which are
impeding efforts  to  assure  adequate  protection of
health and  the environment?  The issues are the  heart
of this  report.   For each issue the following information
is presented:  a description of the  issue indicating why
the  missing information is  necessary;  what is known,
and unknown,  about the issue; EPA's research  role in
the   context  of  other  major  associated research
programs;  EPA's   research  strategy  and  specific
research approach;  and  major  anticipated research
products or milestones.

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Cross-cutting Issues

      It  bears  repeating  that  this   is  a  strategy
document.  It is not intended to be, nor would it serve
its  purpose if  it were,  an exhaustive litany  of  all of
EPA's research projects.   There  are  many  areas of
active EPA  research  which  are not discussed in  any
depth in  this report.  They are excluded for one of  two
reasons.    First, they  may contribute exclusively to
issues which are of lesser importance or  priority than
the ones selected for  this report.   An example of  one
such  issue  is  EPA's  non-ionizing  radiation  research
effort.  Once a significant component of EPA's research
program, studies of  non-ionizing  radiation conducted
during the past five years have  produced a good deal of
useful information.  Based upon this  situation,  EPA's
regulatory  office  determined  that  sufficient  data
already  existed  upon  which  to  base its regulatory
decisions.  As  a  result,  non-ionizing radiation research
is being  de-emphasized within the  overall  research
program  and is  not  considered  to be a major issue
warranting inclusion in Research Outlook 1983.

      The other reason  that  a  research area may not
appear in a particular chapter is because it cuts across
several of the chapters.  Examples of such cross-cutting
issues are  quality assurance,  risk assessment  methods,
regulatory  and  technical support,  and  information
transfer. In some  cases, such an issue of consequence
to several chapters is discussed in depth in the chapter
for which it holds the greatest significance.     This
allows a more detailed  discussion of the  cross-cutting
issue, although the discussion is somewhat distorted by
the  limits  of  a particular  chapter.   In  other  cases,
aspect's of a cross-cutting issue are discussed in several
chapters.

Research Priorities

      It  is  impossible   to   predict   in   detail  what
environmental research will be  necessary over the next
half decade. The context for this  research is  much too
dynamic. Legislative mandates  may be altered, policies
may shift and public  concerns evolve. All these forces
will shape the  details of our future research  program.
In  addition, that  program  will shape itself  as  new
research  information  either  highlights the  need  for
added investigation  or  resolves  the  problem  being
investigated.

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     In a large sense, every one of the issues discussed
in the following document has a very high priority.  The
issues are closely intertwined  — the products from one
issue  providing  the  substrate  for another.    Taken
together, the  approximately 60 issues discussed  in the
following chapters  make  up  one  unified  research
program.   Given this  context,  there  are some  major
research needs  which  can be  identified,  with some
certainty, as paramount:

     Ground-water pollution.  To  control the pollution
of ground water, it is necessary to be able to monitor
underground  pollutant  plumes  and  to  predict  their
behavior.  We are testing equipment and developing
models  to do  both, and are investigating a number of
techniques to destroy or isolate toxic substances.

     Water quality determination.  The use ascribed to
a body  of water determines the quality at which that
water  must  be maintained.   A  water-quality  based
regulatory  approach   requires  the   development  of
accurate, and inexpensive, methods  for determining
water quality.

     Toxicity  measurement  for   complex  mixtures.
Determining the  toxicity of  a complex mixture of
wastewaters as  a  whole would be a far less expensive
process than identifying each of the components  of the
wastewater  and then   attempting  to  determine their
combined effect. We  are developing bioassay and other
techniques that should improve our ability to determine
the  human  health  implications  of   such   complex
mixtures.

     Toxicity prediction for chemicals.  Toxic chemical
testing  is  an expensive  and  time-consuming  process.
Research is being  performed to develop more accurate
and less expensive  test methods and to improve existing
screening methods.

     Determination   of   environmental   exposure.
In order to  more precisely determine the effectiveness
of various air pollution control strategies, we need to
know exactly how  much pollution people inhale.   We
will  be  testing personal monitors which  measure CO in
order to develop accurate exposure data  which can then
be  used as a surrogate for  determining exposure to
other air pollutants.

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      Acidic  deposition  source-receptor relationship.
We must have better information on the relationships
between the sources of acidic deposition precursors and
their  eventual  effects  on  the  receptors  of  that
deposition.   This is  an issue with enormous resource
implications for the industrial and commercial sectors.

      Predictive modeling.   In  order  to  provide the
necessary  tools  to state  and  local decision  makers
responsible  for controlling air  pollution, we will  be
refining  air pollution  models  to better  predict the
behavior of air pollutants  under certain meteorologic
and topographic conditions.

      Biological pesticides.    There  has  been   rapid
growth in  the  development  of  biological  pesticides.
EPA  is performing research  for use in  evaluating the
possible human health  and environmental (non-target)
risks of such agents.

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    Chapter One
HAZARDOUS WASTES

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HAZARDOUS WASTES
Outline:

Introduction
Legislative Mandate
Background
Major Research Issues:
     Issue: What designs make surface impoundments
     more secure?
     Issue: How can air pollution from volatile
     organics be controlled?
     Issue: What information is needed to optimize
     incineration?
     Issue: How can sampling and analysis methods be
     improved?
     Issue: How can health risks be assessed more
     accurately?
     Issue: How can non-volatile compounds be
     measured?
     Issue: How can the quality of sample data be
     assured?

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                 Hazardous Wastes
INTRODUCTION

     The safe treatment  and disposal  of hazardous
wastes  is  one  of  America's  major  public  issues.
Hazardous wastes from industrial production have been
common for  decades, but  only recently has  major
legislation focused on the magnitude of the problem and
on research to help find remedies to it.  Because today's
waste problems differ from  those in the past in terms
of  volume,   toxicity and   resistance  to  treatment,
remedies will need  to exploit  new technologies   and
procedures.

     Hazardous  wastes now include  many man-made
compounds that do not exist naturally.  Some of these
compounds are slow  to biodegrade.  In 1981, in excess
of 50 million  metric  tons of hazardous wastes including
organic    chemicals,  pesticides,   acids,   caustics,
flammables  and  explosives  were  generated  in  the
United States. The extent of health problems caused by
hazardous   wastes   is   still   largely    undefined.
Concentrations at which chemical wastes cause adverse
effects, their latent period  before  manifestation, the
routes  of hazardous  waste exposures and  the chronic
effects   of   such   exposures  on  people  and  the
environment are difficult to determine.

     Congress has legislated, and EPA has developed, a
hazardous waste  program.   The major goal of  this
program is to reduce  risks  to public  health  and the
environment   by   ensuring   sound  management  of
hazardous wastes.

     The EPA research program for hazardous waste in
fiscal year   1983  is allocated  $33  million.    These
resources are distributed among the research disciplines
as   follows:     engineering   and  technology,   55%;
monitoring  systems and   quality  assurance,   22%;
environmental processes  and effects,  15%;  scientific
assessment, 5%; and  health effects, 3%.

LEGISLATIVE MANDATE

     EPA's  mandate for  hazardous  waste research
comes  from the Resource Conservation and  Recovery
Act  (RCRA)  of 1976, as amended;  the  Federal  Water
Pollution Control Act (FWPCA),  as amended; and the
Comprehensive       Environmental        Response,
Compensation, and Liability Act (CERCLA) of  1980.
RCRA is the  vehicle for defining, at the national level,
the minimal  guidelines and  requirements necessary to
protect   human  health  and  the environment  from
hazards posed by the treatment, storage or disposal of
hazardous wastes.

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                  Hazardous Wastes
     RCRA also gives the EPA authority to establish
national  standards  to  ensure  proper  management,
transportation,  treatment,  storage, and disposal  of
hazardous wastes. RCRA requires EPA to develop lists
and  criteria  for  determining  what   constitutes  a
hazardous  waste, standards  that  have  to be met by
handlers  of hazardous wastes, technical  standards for
issuing  permits  to  hazardous  waste  facilities  and
requirements for the authorization of state hazardous
waste programs.

     The Federal Water  Pollution Control Act, which
sets federal  policy  regarding the discharge  of  oil or
hazardous  substances  into   U.S.  navigable waters,
directs   EPA  to  develop,   promulgate  and   revise
regulations  pertaining  to such  discharges.   FWPCA
authorizes  EPA to initiate civil action  for  violations
and to undertake actions  to mitigate damage to public
health or  welfare caused  by discharges.   Although
regulations  implementing FWPCA already exist, they
require periodic updating based on new information and
improvements in control technology.

     The  Comprehensive  Environmental   Response,
Compensation and Liability Act provides authority for a
federal response to the release or threatened release of
hazardous substances.  CERCLA also includes the Post-
Closure Liability Trust Fund.  As a means to achieve its
goals,  CERCLA  established  the  Hazardous  Substance
Response Trust Fund, also known as Superfund. While a
significant amount of scientific  activity is  under  way
relating  to Superfund activities,  this activity  is of a
technical  support  nature   and   therefore   is  not
appropriate  for  inclusion  in this   Research Outlook.
Many of the results from  the  research described  below,
however, will be of use at some point in the  Superfund
effort.

BACKGROUND

      Hazardous  waste  problems have certain features
that, taken  together,  determine the  most  effective
response.   Wastes  at  industry sources  or  already  in
disposal  sites need to be identified, characterized and
classified  as  to  their  composition,   quantities  and
potential health effects.  Sites to be used for disposal
and technology  to be employed at the  sites need to be
evaluated  to  assure that future discarded wastes are
adequately monitored  and  controlled.   Permits  for
operating  sites and for  disposing of  wastes need  to
provide  permittees  with  the  appropriate requirements
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                  Hazardous Wastes
to be followed. Instrumentation to monitor sites and to
assure  compliance or to detect and measure problems
needs to be effective for various types of wastes.

     All of these activities and requirements demand a
solid scientific base of technically sound, field-tested
and proven procedures that supply accurate and timely
information  for solving a specific  hazardous  waste
problem.  Moreover, the data, information and decision-
making processes must be of known  quality to assure
consistent quality control, since much of the regulatory
authority  for  dealing  with hazardous  wastes will  be
transferred  to  state  agencies.    States   will  need
monitoring  methods   for  obtaining  verifiable  data.
Furthermore,   revisions   of   the   hazardous   waste
regulations will occur  periodically  and  must have  a
scientific  data base that is  technically sound.

     A major  problem  facing EPA  is  the relatively
recent  recognition  of  the  dangers from waste and the
dearth  of  scientific data on the subject.  For example,
scientific  analytical methods have been developed for
many  volatile  and  semi-volatile compounds, but  less
progress has been made in developing methods for non-
volatile  compounds.     EPA's   research  program   is
designed to fill major information gaps, both to provide
near-term solutions and to establish  a scientific base
for the longer-term.

MA30R RESEARCH ISSUES

     The  key hazardous waste research  issues are:
o    What  designs  will  make landfills and surface
impoundments more secure?
o    How can air  pollution from volatile organics be
controlled?
o    What information is needed to optimize the use of
land treatment for hazardous waste disposal?
o    What  information is  needed  to  optimize  the
incineration of hazardous wastes?
o    How can the  accuracy and reliability of methods
for sampling wastes and waste sites and for  biologically
and chemically analyzing the sample data be improved?
o    How can the extent of health effects and risks
from hazardous wastes be  defined sufficiently to allow
adequate  levels of protection  to  be  determined while
avoiding  costly   over-control?      Can   rapid   and
economical tests  be developed  which  can be accurately
extrapolated to humans?
o    How can non-volatile compounds be measured?
o    How can EPA assure that the analyses of samples
taken  from hazardous wastes   yield  data of known
quality?
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                  Hazardous Wastes
Issue: What designs will make landfills and surface
impoundments more secure?

     Landfills  and surface  impoundments have  been
used for years as inexpensive  means  of  disposing of
hazardous wastes.  The  design  of many of these sites
followed   haphazard,   conflicting    and   sometimes
erroneous information.  Some of the problems of today,
particularly ground-water contamination, are testimony
to the inadequacy of the earlier approach.  With that
legacy  in  mind,  one of  EPA's    proposed  research
programs is attempting  to develop  the information to
make landfills and surface impoundments more  secure.
The  research focus is on the life span and efficacy of
flexible, synthetic membranes and/or impervious soils
used as liners for the hazardous-waste sites.

     Flexible membrane liners  (FML's) and impervious
soils can be placed on the bottom of a waste site before
the hazardous waste  disposal begins; they can  also be
used to  cap sites once they  are filled.  The liners, if
installed and maintained correctly, contain wastes and
isolate them from the influx  of surface or ground water
that might  cause the waste to escape from the site.
When used  as a  supplement  to clay or soil barriers,
FML's can dramatically increase their  effectiveness.
The  key  design criterion for using FML's and impervious
soils is  whether  they are compatible with the wastes
they are to control:  some wastes  may pass  through
certain   materials used  in   liners,  other  wastes may
chemically  degrade  liners.    EPA  research  projects
evaluate the compatibility of synthetic liners and soil
liners  with wastes  and investigate  techniques  to
monitor the integrity of liners.

      EPA has the leading role in federally  sponsored
FML research,  although  there  are  a  few  other
organizations conducting their own  programs.  A  small
program  conducted  by  the  U.S.  Army   Corps  of
Engineers is looking at liner  compatibility with military
wastes   (e.g.,  explosives).    Private  companies are
developing  new  liners,  but  their product  designs are
hampered by the lack  of precise  descriptions of the
specific  waste mixtures which would require liners.

      EPA's research approach  is to  develop tests to
determine  the   compatibility of  liners  with  various
classes   of  organic  and   inorganic  compounds  at
concentrations likely to  be seen in waste mixtures. The
tests will be for effects on porosity, permeability, and
the  response of  the liners to chemical and mechanical
stress.
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                  Hazardous Wastes
      A  method  will  be  devised  to  predict  likely
leachate compositions based on various concentrations
of  waste  compounds  and  chemical  reactions among
them. The liners will then be installed in test beds and
evaluated  under  actual  field  operating  conditions.
Monitoring and measuring equipment will be developed
to determine the durability of the liner and its ability
to  contain and control  specific  waste mixtures.   The
output of the research will be a set of recommendations
for using liners at waste sites.

      Research regarding  surface  impoundment liners
will also  focus on repairs to  leaking  liners.   New
methods and  instrumentation are  needed  to detect
leaks. The current method is to take periodic samples
from  monitoring  wells   around  an  impoundment.
Research is focusing on the use of geophysical  methods
and sensor technology  to monitor the  unsaturated soil
zone.  This monitoring will detect pollutants  from a
leaking liner before they reach the ground water.  Once
a leak has  been detected, however, methods are needed
to plug it.   Techniques  will be investigated for bonding
a patch to the leaking liner.

      A manual with  landfill and surface impoundment
design recommendations will  be  available in  1983.   It
will be updated periodically as more  is learned about
waste characteristics  and liner  compatibility.   The
leak-sealing methods will  be  developed in 198^.   In
future years, emphasis will be  put on leak detection.

      Other means to  control the flow  of waste-site
leachate will be studied to match the type of  control
methods  with  the nature of the leachate problem and
the  characteristics of  the waste site.  This  work  is
important  because  ground  water  and surface water will
become contaminated as they come into contact with
the leachate plume.  This, in turn, can affect drinking
water aquifers and could, depending on the seriousness
of  the contamination,  lead to the closure of  drinking
water sources.

      The rate of leachate flow is  determined by the
physical and chemical characteristics of the waste and,
to a lesser extent, by the  subsurface geology.  The key
factor here is the amount of  water  that percolates
through the waste.  This is affected by the amount  of
water in the  wastes, entering the  landfill, or in the
surrounding land.   Rain-water inflows to landfills, for
example,  can  cause leachate  flows  that  might  be
avoided if the  waste were isolated from the inflow.

      The  research  at  EPA is  developing   control
methods  and   technology  for  abating  the  flow  of
leachates as well as methods for collecting and treating
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                  Hazardous Wastes
leachates prior  to their  discharge.   Such technology
includes  bentonite dams,  slurry trenches  and French
drains.  Technical handbooks presenting spill prevention
and treatment/removal techniques  will be  published in
1984.  Biological  controls will  include the use of  the
existing  or modified  microbes that will decompose
waste to inert or harmless substances.   The result of
this research will be  a set of alternatives for resolving
problems  at  waste  sites  with  migrating  leachate.
Monitoring techniques for the unsaturated soil zone will
be described for use in  determining the likelihood of
future escape of  leachate  to the  ground water.  The
results will be available for field use by 1985.

Issue: How can air pollution from volatile organics
be controlled?

      Waste  materials disposed of  in  a landfill  or
surface impoundment  may  produce air  pollution  when
either the  materials themselves volatize (evaporate) or
when  products   of   chemical  reactions  among  the
materials evaporate.  Such volatile organic compounds
(VOCs)  found in the air  around landfills  and  surface
impoundments may  produce health and  environmental
effects and unpleasant odors.

      EPA's research program is developing techniques
for measuring and predicting the amounts and rates of
VOC  emissions.   One prediction method will be used to
estimate the amounts that will move up through  a  soil
cover.  Research projects will identify the effects of
barometric pressure  and  waste decomposition on  the
movement of  volatile substances.   Results  will  be
available in 1984.

      Another  prediction  method  will  describe  the
movement of VOCs laterally through the  soil.   After
field  verification  is  completed in 1983, the method  will
be   used   to  determine   effective    VOC   control
technologies (e.g., vents and barriers) and to decide  how
far buildings  must be from  a site to  avoid  exposing
people.

      The verified prediction and measurement methods
will be used  to  evaluate  the  magnitude of the VOC
problem so that site designers and permit reviewers can
compare performance estimates with actual emissions.
This  evaluation  and  comparison  will   provide  the
technical basis  for potential  regulatory action and for
identifying future research needs.

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                  Hazardous Wastes
Issue: What information is needed to make optimum use
of land treatment for hazardous waste disposal?

     Land  treatment  of  hazardous  wastes  involves
tilling  (incorporating) it  into  the soil  to enable the
natural  biological, chemical and physical  processes of
the  soil  to  decompose,  destroy  and  detoxify  the
hazardous compounds. The major benefits of using this
natural  assimilative capacity of soil are two-fold: first,
it  can be a very cost-effective  approach, and second,
through  land  treatment  such  processes  as biological
degradation,  chemical   transformation   and  simple
immobilization can convert some wastes into innocuous
compounds rather than being stored in a hazardous form
in landfills and surface impoundments.

     The concept  of  land  treatment  for  hazardous
wastes is not new.  Petroleum companies  have  used the
technique for  more than 20 years with  good success in
treating substances  such  as  tank  bottom   residues.
EPA's research will build upon the information  garnered
from these  earlier  successes and will extend  the land
treatment  option  for a  broader range  of  hazardous
wastes for which conventional  disposal is economically
and environmentally undesirable.  Research will focus
on understanding the subsurface  physical, chemical and
biological  processes  that affect  the  movement  and
degradation of wastes.

     Land treatment  studies begin  in the laboratory,
then move to a greenhouse environment and, finally, to
actual   test  sites  if  good treatability  potential  is
indicated.  EPA  currently has a test area of more than
100 acres which is available for land  treatment studies.
Laboratory tests will be made of actual waste  mixtures
supplied by cooperating industries.   The mixtures will
be characterized to determine the amounts and types of
waste compounds they contain.  The land at  the  test
site will be characterized to determine its physical and
chemical parameters and likely  biological responses to
the wastes.  The mixture will then be spread on the soil
and tilled.

     Measuring  and monitoring instruments and sample
taking  will  reveal  the degree  of  biological  activity
taking place.  Soil column testing in the laboratory will
determine the migration  of pollutants and the loading
rates.   Variables  will  be evaluated  to  determine the
optimum  land  treatment  process.    Such  variables
include  loading  rate  of waste initially  applied to the
land, different application and  incorporation methods,
amount  of soil moisture, pH, and  soil fertility.

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                  Hazardous Wastes
     To monitor land treatment sites for contaminants,
several  statistical   detection  procedures   will   be
employed.  The monitoring network design will be based
on the  statistics of  spatially correlated  variables.   By
using  these  techniques,  a   range  of  correlation
coefficients  can be  computed to  minimize cost  and
maximize coverage of the sampling design.  Since  the
monitoring must be repeated over time, the monitoring
network design will  include  time-series  analysis  to
minimize   cost  while   maintaining  an  acceptable
probability of coverage.

     The hypothesis testing of monitoring  data  will
compute both the type I error  (alpha,  probability of a
false positive)  and type II error (beta, probability of a
false negative).  Such procedures will be appropriate for
multiple variate analysis with unequal  variances. EPA
will  develop  guidance  on the  design of monitoring
networks  for  use  by  regional personnel  in  issuing
permits.

Issue:  What information is needed to optimize the
incineration of hazardous wastes?

     Incineration is  an effective method for destroying
hazardous wastes. Its use in the past was limited by its
relatively  high cost when  compared  to  landfill  and
surface impoundment alternatives.  Now, though, these
alternatives  are becoming  more   expensive  and  less
available  for certain wastes and  geographical  regions.
Extensive  knowledge has  been  produced under  this
program  and is being  applied under the  Superfund
program.   Further information  may help  to optimize
incineration  conditions   in  order  to  achieve  the
maximum  destruction  of wastes  at the lowest cost.
EPA research will develop scientific data  for  existing
incinerators  to describe  the best  operating  conditions
for incinerating certain types  of hazardous wastes  and
to  define air  emissions  which may  result  from  the
incineration of certain  types of hazardous wastes using
various incineration processes.

      The  program  will  run test  burns in pilot-scale
incinerators  as well  as  in  commercial incinerators.
EPA has a Combustion Research Facility in Pine Bluff,
Arkansas,  in which  to  conduct the  pilot-scale  test
burns.   The  facility is  fully instrumented to allow
determination  of the  various parameters  associated
with incineration in  rotary kiln  and  liquid injection
incinerators.

      The  research  program   will  first characterize
waste for thermal destructability  and  then burn these
wastes at  the EPA  research facility  to  assess  the
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                  Hazardous Wastes
effectiveness   of   the  incineration  process.    The
parameters to be evaluated include temperatures in the
incinerator, dwell  time  of the  wastes  in  the  high
temperature  zone,  the Btu content of  the waste, the
oxygen content  of  the mixture, the optimal  air/waste
ratio,  waste  injection  methods,  the  need  for  an
afterburner  to  assure  complete  destruction  and  the
types of  analysis and sampling techniques needed.  One
major  concern  to   be   investigated   involves   the
establishment of thermal destruction conditions  that
are necessary to eliminate the formation of additional
toxic  substances   which  may  form   under   current
incinerator conditions.  Additionally, air emissions from
the incineration will  be characterized  to  determine if,
and  at what concentrations,  hazardous compounds  or
toxic metals are being emitted.

     The information collected from  the tests will be
used to allow scale-up to  full-sized incinerators.  Field
verifications     will    determine    likely   operating
efficiencies and optimal methods  to be used in actual
hazardous waste control  sites.   The  composition  and
quantities  of  combustion products produced  will  be
analyzed  to  ensure  that no  harmful  pollutants  are
released  to  the environment.   EPA has  established  a
permit  assistance  team   to  help  permit writers  to
evaluate  permit applications.    The   results  of  this
research will help that team to assess  the data included
in permit applications  and to establish  necessary  trial
burn parameters and criteria for particular wastes to be
burned in specific types of incinerators.

     In  addition  to  the  studies   of  conventional
incineration   processes,  a   research  program   will
investigate   advanced   high-temperature   industrial
processes.    The  program  will  field  test  full-scale
operating units  to  evaluate unit performance and to
determine  conditions  that  would limit the processes'
effectiveness.

Issue:  How can the accuracy and reliability of methods
for sampling wastes and waste sites and for biologically
and chemically analyzing the sample data be improved?

     Some of the current state-of-the-art methods for
analyzing hazardous wastes and waste site samples  have
not  undergone  the rigorous  evaluation  necessary  to
define  standard confidence  limits  for the data  they
produce.  Such limits, stated as  the  "plus-or-minus"
confidence limit of  each  data point, are especially
important when the measured concentration is near the
regulatory decision limit  used to  determine whether a
waste is  hazardous  or a site sample indicates a health
or environmental problem.
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                  Hazardous Wastes
     Current programs use analytical methods based on
technology  developed  for  EPA's  water   monitoring
programs.  Confidence limits of these  methods can now
be  applied  to  the  analysis  of  aqueous  samples.
However, only limited information is available for their
application  to  hazardous waste samples  and samples
from waste sites (e.g., soils, sediments and solids).

     Because of this limitation, EPA  has placed a high
priority on developing quality assurance information on
various  methods.    A data  base  will  be  developed
consisting of standard reference materials containing
priority  pollutants.    This  will  serve  as  a  single,
traceable source of known  purity standards for  RCRA
monitoring activities.

     EPA   researchers  are   also  evaluating  new
technology and developing improved quality control and
assurance procedures to  reduce the  cost  of analyses
while simultaneously narrowing the confidence limits of
the  resulting  data.   Guidance  documents will  be
produced that define  the confidence limits of  the
current  methodology and describe  improved protocols
and technology. Finally, standardized  methods will help
to support specific RCRA regulatory requirements such
as methods  for characterizing waste  as hazardous  due
to toxicity, corrosiveness, ignitability, etc.

     One   EPA   study  will   improve   the  current
extraction   procedure   for    the    RCRA  toxicity
characteristic.  The procedure  now in use  can only be
applied to  a small list of toxic materials and does not
yield  an extract  that  is amenable to  bioassay.   The
improved procedure, based  on a flow-through column
of  the  waste, should yield  an  extract  suitable  for
bioassay.    The  procedure   is  being  evaluated  to
determine  its reproducibility and how well it reflects
actual waste disposal situations.  Results are expected
in 1984.  Other research includes developing standard
protocols for  other  RCRA   characteristics such  as
ignitability  (flash  point),  corrosiveness  and reactivity
due  to  toxic  gas generation.   These protocols  will
undergo  testing  to   establish their  precision   and
accuracy during 1984 and 1985.

      Another research effort is evaluating the use of
bioassays for  determining  the toxicity of  hazardous
wastes.  Standard protocols for the Daphnia Magna and
Ames  Test  bioassays will  undergo  single  lab  and
collaborative testing during 1983.  Other bioassays will
be identified and  undergo similar protocol development
and evaluation during 1984-1985.
                         18

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                  Hazardous Wastes
     The evaluation of  methods to analyze hazardous
wastes  will  continue.    Collaborative  testing  of an
analytical    protocol    for    measuring    medium
concentrations (from one part per million to 100 parts
per thousand toxics concentration) will be completed in
1983, and evaluation of methods to extract organic and
inorganic samples (soxhlet vs.  liquid-liquid extraction
for organics;  digestion procedures for inorganics)  will
be reported on in 198^.  A specific analytical  method
for dioxin in hazardous  waste is being standardized.
Methods are required that detect dioxin  at very  low
concentrations (100  parts  per  trillion) even  in  the
presence of higher  concentrations of other substances.
An initial dioxin  protocol will be provided during 1983.
Efforts  will  then  be  initiated  to  provide  similar
protocols  for  dibenzofuran,  another   highly  toxic
compound, by 1985.

     Projects  to improve  the  quality  of hazardous
waste  data and reduce the cost of analysis are  under
way.  One analysis method, known as pulsed positive ion
negative ion chemical ionization mass spectroscopy, has
the  potential  for  improving the  sensitivity  of mass
spectroscopic analysis  of very toxic materials.   The
method  is  being evaluated  and  a  protocol  will be
produced in  1983.  Tandem mass spectroscopy  for the
quick screening of hazardous wastes will be reported on
in  1984.   Fourier  transform infrared spectroscopy is
also being investigated  for use in the analysis of high
concentrations of hazardous waste.

Issue:  How can the extent of health effects and risks
from hazardous wastes be defined sufficient to allow
adequate levels of protection to be determined while
avoiding costly over-control?  Can rapid and economical
tests be developed which can be accurately extrapolated
to humans?

     Section   3001   of  RCRA   requires  EPA  to
promulgate criteria for  identifying the  characteristics
of  hazardous  wastes  and  to  provide  a  listing of
hazardous wastes.   Because of the  large  number of
wastes to be screened, it may prove useful for the EPA
to  develop a  battery  of rapid,  inexpensive  bioassay
prescreening tests that prioritize hazards from complex
chemical mixtures by  determining which  wastes  are
most  important for toxicological characterization. If
the  prescreening shows a  waste  to  be  potentially
hazardous,  then a  second  method may  be used to
determine   affected    health   endpoints    and   the
environmental  levels of exposure at which effects can
be  observed.  Results from this second method will be
                         19

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                  Hazardous Wastes
used in the  process of analyzing a waste  for listing or
delisting  as a  hazardous waste.   Currently  existing
methods have not been validated for complex mixtures
and  not  all  endpoints  have  rapid,  inexpensive  test
methods to quantify potential effects. Research will be
conducted to develop such methods.

      Which testing procedures can be used to estimate
relative  degree  of  hazard  is  the  major  issue for
determining health hazards from chemicals.  The goal is
to develop a group of tests that will allow estimates of
relative hazard to be made at reasonable  costs.  EPA's
approach to solving this problem is to validate  shorter-
term  toxicological  testing  procedures  for  ranking
hazards  to  human health.   Currently  that  ranking  is
obtained by more conventional, but more expensive test
procedures.

      To  predict  the  ranking   of  hazards  to human
health, it is necessary to identify two different  types of
toxicity:    responses  which  result   from  genotoxic
effects, on the one hand, and toxicity to target organs,
on the  other.  This research is  essential  for biological
testing of results  obtained in the field  to be validated
for  human  health effects.  In  some cases substantial
evidence indicates   qualitative  correlations  between
short-term  and  more conventional testing  procedures.
However, use of  data from  the short-term tests for
quantitative  estimates  of   health  risk  is   not  yet
practical.  EPA  research  projects  will  establish the
cause-and-effect  relationship between the short-term
indicator of adverse  health  effects and overt  diseases
and   will  determine  the   quantitative   relationship
between  does-responses,  the   indicators  and  the
diseases.  The  first  three years of the  research will
emphasize establishing empirical relationships  between
indicators and the production of diseases. Key goals  of
this  work  are  the  determination  of  which  testing
methods are clearly  irrelevant  to human health effects
and  the establishment of cause-and-effect relationships
between indicator and disease for the final validation of
health effects models.

      By  1985, research will complete an evaluation  of
an   inexpensive,   qualitative   prescreening   protocol
integrating existing  methods  for  predicting biological
activity (chronic  toxicity, mutagenicity,  neurotoxicity,
etc.)   The  report  will  assess  the efficiency of the
protocol  for  application to  RCRA materials  such  as
complex  mixtures of raw wastes and  leachates.  The
protocol  is  being developed  to provide the  data  to
support  setting  of  first-level  priorities using   an
integrated battery of tests.  Also by 1985,  initial field
testing will be completed for an integrated protocol of
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                  Hazardous Wastes
a second-level, confirmatory battery of existing tests.
The protocol will quantify levels of dose-response using
a single set of  test  animals  for the  specific  toxic
hazards  of   carcinogenicity,   mutagenicity   system
toxicity, neurobehavior  and teratogenicity.      When
proven, this  protocol,  by  quantifying  risks, could be
used as a basis for determining if a waste is hazardous.

Issue:  How can non-volatile compounds be measured?

     Current EPA monitoring methods are, to a large
degree, applicable only to the volatile and semi-volatile
compounds  that  can   easily   be  analyzed  by  gas
chromatography  and  GC/MS.   Many potentially toxic
compounds (e.g., larger molecular weight  compounds)
are not easily analyzed by the current protocols.  While
monitoring methods exist for some of the less volatile
compounds — for example, liquid chromatography can
be  used  for  some   pesticides  — current   routine
monitoring   procedures cannot  adequately  analyze
intractable compounds  (those not  easily removed from
water  or similar matrices) or  non-volatile  compounds.
This is significant because there  is  a  considerable
proportion  of  non-volatiles  in  samples  from  some
hazardous waste  sites.  EPA research will attempt to
identify or develop analytical methods to measure these
of compounds.

     Two  methods being  studied  are high  pressure
liquid chromatography and triple stage quadrapole mass
spectroscopy.  The mass spectroscopy  method will be
initially evaluated in  1983 for  its application to  non-
volatile toxic chemicals.  Pending the success of that
evaluation, the method will be fully developed in  1985.

Issue:  How can EPA assure that the analysis of samples
taken from hazardous wastes yield data of known
quality?

     Analyses of hazardous wastes are  being conducted
under  the auspices  of EPA  throughout  the  United
States.   Rigorously  defined  analytical  protocols  are
required to assure that the laboratories conducting the
analyses  collect  accurate,   quality-assured   data.
Quality assurance is needed to:

o    develop/evaluate   analytical    standards   for
instrument calibration,
o    develop/evaluate   reference    solutions    for
evaluations of laboratory performance,
o    develop/evaluate  reference   materials   (soils,
sludges, etc.) of known composition for  intercomparison
studies,
o    validate  sampling,   analytical  and   biological
methods, and
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                  Hazardous Wastes
•    determine   equivalency   of    new   sampling,
analytical and biological methods.

     EPA  has  developed and  is  applying  analytical
protocols  that  support   both  RCRA  and  CERCLA
monitoring responsibilities.  Quality assurance  is a key
part of this work. EPA will also maintain a repository
of calibration standards through 1985. This repository
will  support   RCRA  requirements,  as will  reference
materials  and solutions developed by  EPA to evaluate
laboratory performance and to ensure comparability of
analytical  data.     On-site   evaluation  of   RCRA
laboratories   and additional   support  will  also  be
performed by EPA.
                         22

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  Chapter Two
WATER QUALITY

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WATER QUALITY
Outline:
Introduction
Legislative Mandate
Background
Major Research Issues:
     Issue:    What  are  appropriate  methods  for
     determining attainable uses for a water body?
     Issue:    How  should  laboratory-derived  water
     quality criteria  be modified  to apply  to site-
     specific conditions?
     Issue:  How can wasteload  allocation techniques
     be used  to translate applicable water  quality
     standards   into  allowable  pollution  discharge
     loads?
     Issue: What is the best way to assess the impacts
     of the ocean disposal of wastes?
     Issue:   What  are the  dynamics and  biological
     availability of  pollutants in sediments?
     Issue: What analytical test procedures and quality
     control  methods  are  necessary  for  accurate
     measurement  of  habitat?  What  monitoring is
     needed to quantify water pollutants?
     Issue:  What are the key  technical and scientific
     factors that limit the effective treatment and use
     of   sludges   from   municipal   and   industrial
     wastewater treatment?
     Issue:   Are occurrences of infectious diseases
     increased  by  certain wastewater  treatment  or
     sludge disposal practices?

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                    Water Quality
INTRODUCTION

      EPA's water quality  research program includes
both  an  emphasis on a  field-oriented water-quality
based approach to pollution control, and consideration
of the  chemical and  biological  impacts of the ocean
disposal of wastes. The research will include studies of
ecological effects,  process and systems engineering,
health effects and monitoring methodologies.

      With the nearing completion of effluent  guidelines
and the application of technology-based controls,  EPA
will now give more emphasis to the implementation of a
water-quality based  approach.  States  will focus  on
those water bodies for which pollution  abatement and
control decisions are most needed to prevent or reverse
the impairment of a designated use.

      The  water-quality   based  approach  to  water
pollution control matches control requirements  to site-
specific uses.   Each use  of  a body  of water  (e.g.,
recreation, fishing) calls for a minimum water  quality.
Once the use of  a stream  segment or  water  body is
defined, various alternatives to achieve or maintain the
water quality appropriate to the designated use can  be
evaluated, and  cost-effective controls can be selected.
This process involves consideration of  existing water
problems, of community goals for the  use  of water
resources, and  of costs and benefits of  various control
strategies.

      Although  significant  progress has  been made  in
developing  water-quality   based   controls,  additional
technical  information is needed to facilitate pollution
control decisions.    The  technical information  must
provide decision  makers with a basis for the selection
of water  pollution controls.  Standardized analytical
and monitoring methods are needed for  the assessment
of local water  quality through  bioassay and  biological
survey, as well as for compliance with water quality
standards  and discharge limits specified in permits.

      Although  water pollution control programs  will
increasingly  emphasize   the   water-quality   based
approach, the technology-based approach that has been
applied  over  the past decade will  be  continued.   The
Agency's construction grant program will continue to  be
a major part of  the  Agency's water pollution  control
efforts.

     Over the  last year,  substantial progress has been
made  on  promulgation  of  final,  technology-based
standards, based on the best available technology. EPA

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                    Water Quality
has completed  most of  the technical and  economic
studies  needed to support the promulgation of Agency
effluent guideline regulations for major industries.  For
those   pollution  sources  not  subject  to  effluent
guidelines, permitting agencies will issue individual best
professional judgment permits for pollution discharges.

     The second major water quality research issue is
ocean disposal of waste.  As a result of the decision in
City of  New York v. EPA, 543 F. Supp.   1084 (S.D.N.Y.,
1981),   EPA  is  proposing  revisions  to  existing  ocean
dumping regulations.  Under these revisions, EPA will
consider and balance all the relevant statutory factors
of Section 102(a) of the  Marine Protection, Research
and Sanctuaries Act in making permit decisions.  This
approach requires careful assessment of the role of the
oceans  and   coastal  waters  in  the  assimilation  of
municipal and industrial waste  and dredged materials.
It also  requires  the ability to  predict  the impacts of
ocean disposal, to evaluate  alternative  disposal options,
to select appropriate disposal sites for specific wastes,
and to detect disposal-related problems.

     The ocean disposal research program  will provide
the  information necessary to  support scientifically
defensible  decisions with regard to  ocean disposal waste
management.  EPA, in conjunction with other federal
agencies, will also  seek  to establish  uniform criteria
and methods for determining unreasonable degradation
or  irreparable  harm  to  the disposal sites.   Ocean
disposal issues are expected to be a major EPA concern
over the next five years.

      The  water quality  research program  for  fiscal
year  1983 is  allocated a total of  $30.6 million.  This
total is divided among three subgroups: water quality
research, $14.6 million; municipal wastewater  research,
$11.1 million; and industrial wastewater research, $4.9
million.   The total resources for  the water  quality
program  are distributed  among  the  major  research
areas as  follows:   engineering  and technology,  34%;
environmental processes  and effects,  26%; monitoring
systems and  quality  assurance,  18%;  health  effects,
12%;   Great  Lakes  research,  8%;   and   scientific
assessment, 2%.

LEGISLATIVE MANDATE

      The  Clean Water Act and the  Marine Protection,
Research and Sanctuaries Act both  address protection
of  the  nation's  water quality.  The objective of the
Clean  Water  Act  is  to  restore   and maintain  the
chemical,  physical and  biological  integrity  of  U.S.
waters.   The  objective  of  the   Marine  Protection,
                         26

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                    Water Quality
Research and  Sanctuaries Act  is to regulate the types
and  amounts  of  materials  which,  if  dumped  or
discharged  into  ocean waters, could adversely affect
human  health,  welfare, amenities  and  the  marine
environment,   ecological    systems    and   economic
potential.  The latter act requires compliance with the
London Dumping  Convention,  to  which  the  United
States is a contracting party.

BACKGROUND

     Although  much   progress  has   been  made  in
establishing a  scientifically sound data base for  making
water quality  management decisions,  major information
needs remain. EPA research  will focus on the following
problem areas.  First,  it is  possible  that the  national
water  quality criteria  are  inappropriate  for  certain
water  bodies, thereby  imposing  unnecessary  control
costs.   Imprecise  linkages between in-stream  criteria
and  water  uses may make  it difficult to define the
benefits of achieving the criteria for particular water
bodies.

     Second,  there   is  a   need   to  give   greater
consideration  to  sediment   impacts.   Current  water
quality  criteria  address effects in the water  column,
yet  many  toxic pollutants  and nutrients  end  up in
sediments.   It is difficult to  assess with confidence the
importance  of sediment contamination, or to  relate
pollutant levels in sediments  to effluent discharges.

     Third,   reliable    and    low-cost   methods   of
identifying  certain  chemical  pollutants  are  being
developed.

     Fourth,  more information is  needed on chemical
class interactions  with the  nutrients  and  pollutants
ingested by aquatic life forms. Availability of this type
of information would greatly improve the states' ability
to understand  the biological health of  their waters.

     Fifth,  more  research  is  needed  on fundamental
control processes  in  order  to make  more  accurate
assessments  of  costs   and   benefits.   In  addition,
information is needed  on  the performance, costs and
water  quality impacts  of innovative  and  alternative
(I/A) technologies (constructed under the I/A provisions
of the Clean  Water  Act)  and of advanced  treatment
technologies.

     Sixth,  the  quantities of sludge  and septage from
treating  wastewater are large.   More information  is
                        27

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                    Water Quality
needed regarding beneficial uses of these materials as a
disposal  option.    Municipalities  and  industry  need
accurate information about the process engineering of a
broad range of sludge treatment and disposal options.

      Seventh,  there  are insufficient  data  to  fully
evaluate the occurrence  of  infectious and chemically
induced diseases which may  result from current  and
anticipated wastewater-sludge treatment and disposal
practices.    Additional  information  is  necessary  to
assure that treatment  processes preclude human health
hazards.

      Eight,  developing   site-specific  water  quality
criteria using the chemical-by-chemical  approach  can
be costly.   There is a  need for new toxicologic testing
methods,  applied directly to  effluents  and  receiving
streams, which  can predict chemically  induced toxic
effects in humans and  aquatic organisms.  There is also
a need to develop new protocols for developing site-
specific criteria which are less resource intensive.

MAJOR RESEARCH ISSUES

      EPA's research  programs will  provide  scientific
products which address the concerns  raised above  and
assist  the  states in the implementation  of the  water-
quality based  approach.   The   major   issues  being
addressed by EPA research are:

o     What are   appropriate methods for  determining
attainable uses for a water body?
o     How  should  laboratory-derived  water   quality
criteria   be  modified   to   apply   to   site-specific
conditions?
o     How can wasteload allocation techniques be used
to  translate applicable  water quality  standards  into
allowable pollution discharge loads?
o     What is the best way to assess the impacts of the
ocean disposal of wastes?
o     What are the dynamics and  biological availability
of pollutants in sediments?
o     What  analytical  test   procedures  and  quality
control    methods  are   necessary   for   accurate
measurement of  habitat?  What monitoring is needed to
quantify water pollutants?
o     What are the key technical  and scientific  factors
that limit the  effective  treatment and use of  sludges
from wastewater treatment?
o     Are  occurrences of infectious  diseases  increased
by  certain wastewater  treatment or sludge  disposal
practices?
                        28

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                    Water Quality
Issue:  What are appropriate methods for determining
attainable use for a water body?

     The  water-quality  based  approach  focuses  on
protecting  water uses.  EPA has proposed that states
may employ  a  "use-attainability  analysis"  to  help
determine  realistic water  use goals for specific water
bodies.  To do so, the existing  system is  assessed to
determine   the   overall   health  of   the   aquatic
environment,  the  maximum  biological  potential  is
assessed, and the physical habitat features necessary to
achieve desired uses  are  determined.  Following  the
development of  these  data,  costs  and  benefits  are
compared and  a decision is made with regard  to  the
proper control levels needed to attain a specified use.

     There is  currently considerable  information  that
could  be  used  to   assess  the  health   of  aquatic
environments, but there is no  systematic  method for
integrating it into a comprehensive, useful and accurate
statement of the condition of a  water body.   EPA  will
continue to assess and improve  existing methods,  and
will  combine the most suitable physical, chemical  and
biological measures into an overall assessment  protocol.

     In coordination with the states,  EPA will develop
protocols to aid in field assessments  of specific sites.
These protocols will be flexible, and will be arranged in
such a way that state and local officials  can compare
the benefits of different levels of pollution control.

     Part   of   the   use-attainability  analysis  is  a
determination of the biological condition  of  a body of
water.   To conduct such analyses, states  need better
assessment procedures.  EPA  is evaluating current bio-
monitoring methodology, and  is designing new methods.
The  factors  to  be   considered in  detecmining  the
biological  condition of an aquatic system are water
quality,  physical  habitat,  hydrology  and  biological
interactions.  EPA will develop a method to combine
data from  these categories into a description  of  the
condition of the aquatic system, extent and probable
causes  of   degradation,  potential  for recovery   and
possible corrective measures.  For example, one project
is  examining the use  of fish  community analyses  as a
substitute for a complete  biotic analysis.  The goal of
this  research is to  produce  a set of guidelines for use in
assessing   the  overall  conditions  of  an  aquatic
ecosystem.   The guidelines will be produced  by 1984.
They will be  reviewed, evaluated and  field tested so
that, by  1986, a valid set  of  guidelines should  be
available.
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                    Water Quality
     To predict the levels of use that could be attained
in a  body of  water  —  the  second step of the  use
attainability  analysis  ,— requires research  to  detail
overall  water-body conditions.  At some point a water
body approaches its maximum biological potential  and
cannot  realistically be improved further.  The problem
facing  the  states  will  be  how  to  determine  the
biological potential of  specific  water bodies when only
limited   analytical   techniques  and   resources  are
available.    EPA's   research   program  will  develop
methods  to   describe  the   potential  of   aquatic
ecosystems  and  will  demonstrate  the  methods  on
waterways in various regions of the country.

     The traditional approach to determining biological
potential   has   been   upstream-downstream   studies.
These studies are costly  because each stream must be
studied  twice.   They  are also imprecise because it  is
uncommon to  find a  clean upstream  site sufficiently
similar  to the  downstream  area.  Better methods are
needed.

     Current research is aimed at estimating biological
potential  by  correlating regional  patterns of land use,
geology,  soil   types,  potential   natural  vegetation,
climate and  topography  with physical,  chemical  and
biological characteristics of streams.  Several projects
are under way.  In Ohio,  100 field sites will be used to
determine whether regional patterns  correlate with
stream  characteristics and aquatic  community  traits.
In Oregon, biological  information  is  being  combined
with fish  collection records and historical surveys as a
way to estimate  system potential.   In Montana,  fish
data bases will be correlated with  regional terrestrial
characteristics. Results from these studies will  include
maps that show "attainability  regions" for the  studied
states and an  indication  of whether computerized  fish
data may suffice  for  future use attainability analyses.
This effort will be completed in 1985.  If biological and
chemical  correlations  are encouraging, future work will
extend the methods to other regions.

      The third part of the  use  attainability analysis is
to determine the physical habitat features needed for a
desired use.    One possible approach is to correlate
specific  levels of  use  with  specific  environmental
requirements for those uses. EPA research will develop
site-specific   methods  to   determine  water   quality
criteria, and  the means to relate these criteria to uses.
Physical habitat guidance will  be developed for other
environmental  characteristics  such  as hydrology  and
physical  habitat   features  (e.g.,  benthic  substrate,
sediment   quality,  riparian  characteristics,  channel
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                    Water Quality
morphology and in-stream cover). This information can
be used to help decide whether it is more cost-effective
to attain a use by improving  the water quality  or by
changing the physical habitat conditions.

      EPA's research program will identify and quantify
the physical habitat  conditions  required for attaining
selected beneficial uses for water bodies.  Initial effort
will focus  on factors that are  needed for maintaining a
healthy biological community rather than on improving
fishing or  the assimilative capacity of the  water body.
Data  for the research will be  collected  from  other
federal agencies and states.  If the data are found to be
inadequate, a  research  program will  be  designed to
obtain  the  data  necessary.    One  approach  being
considered is a computerized  data base of organisms
and their environmental requirements.  The data base
would be structured so that either the expected species
at a  site or  the  required environmental conditions for
specific species could be determined.

      Planned research results include:

•     Identification     and     recommendation     of
biomonitoring methods applicable  to use attainability
analysis, 1984.
•     Evaluation  of methods for using fish  community
measures as  a surrogate for more  intensive surveys of
the entire ecosystem,  1985.
•     Development  of  procedures   for   determining
biological  potential  of  stream  ecosystems based  on
ongoing studies.  (Oregon, 1984; Ohio, 1985).
•     Definition of selected physical habitat criteria for
stream ecosystems, 1986.
•     Development of  an aquatic organism toxicity data
base  and  protocol for developing site-specific  criteria
for biotic communities which are habitat limited,  1984.

Issue: How should laboratory-derived water quality
criteria be modified to apply to site-specific
conditions?

      As EPA and the states emphasize a water-quality
approach  to  pollution  control, water quality goals  will
be defined for water bodies by designating the use to be
made of the water and by setting the criteria necessary
to protect the use.   These criteria are numerical or
narrative  descriptions   of   the   concentration   of
pollutants  which  cannot be exceeded if the  uses of the
water body are to be met.

      In many cases, states adopt national water quality
criteria  developed by EPA  laboratories for achieving
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general levels of  quality.   However, because  these
criteria are laboratory-derived,  are  meant  to  apply
nationwide, and are used to protect all types of aquatic
systems, they  cannot take  into  account site-specific
factors.  The national criteria may be under- or over-
protective  at a specific  site  for  three  reasons: first,
species at  a site  may be  more  or less  sensitive than
those  used to  derive the  laboratory-based  criteria;
second, the physical and chemical characteristics of the
water  at a site can alter the biological availability and
toxicity  of polluting substances;  and third, aquatic
organisms can adapt to pollutant levels via a variety of
physiological  processes.   EPA's  research program  is
developing  the information  needed  to  describe  the
modifications necessary to make the  national criteria
more site-specific.

     The   problem   regarding   species  sensitivity
differences arises because  the  national criteria  are
based  on the responses  of trout,  salmon, and penaeid
shrimp to  pollutant  loadings.   These organisms  have
been shown to be especially sensitive to some materials
and, therefore, their responses may not  be the proper
basis for establishing water  quality standards at  a site
populated   with   differing   species.     The  species
sensitivity  differences will be resolved by developing a
data base that describes  aquatic organisms' acute and
chronic  responses  to    different  levels  of  toxic
compounds.  The  data base  will help states or permit
writers relate species to acceptable pollutant loads for
maintaining water  uses.  Species  data  also can be used
to develop  criteria for water bodies  in which habitat
conditions  limit biological diversity. Existing data will
be used to  identify species/compound combinations that
need further testing before they can  be put into the
data  base.   Early indications  are that  site-specific
criteria which consider species sensitivity may change
existing criteria at some  sites by as  much as two to
three orders of magnitude. Results of  the research will
be available in 1984.

     The second  problem  with the national criteria  —
that  physical  or  chemical  characteristics  of  water
systems alter toxic effects — has been demonstrated  in
a  number   of cases.   For  example,  hardness,  pH,
suspended solids and salinity are known to influence the
concentrations  and   bio-availability,   and  thus  the
toxicity, of some heavy  metals, ammonia  and other
chemicals.    Research  into  the  effects  of water's
chemical  and physical properties on toxicants will be
conducted   with  chemical models.    One  model  will
develop empirical relationships  between  a compound's
toxicity and the major water variables.
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                    Water Quality
      A third problem is the fact that aquatic organisms
can   adapt  to  pollutant  levels   via  a   variety  of
physiological  processes.    Research  has  shown  that
aquatic organisms produce detoxifying substances when
under stress.   These  substances act as  a sink, binding
contaminants  that,  if   unchecked,  could  result  in
mortality. It is important that this adaptive process be
fully  understood  and  properly   accounted  for   and
measured  in  environmental  assessments,  especially
those pertaining to use attainability, standard setting
and wasteload allocations.

      Planned research results include:

•     Feasibility report  on  using  chemical  speciation
models to derive site-specific criteria, 1983.
•     Report   on   feasibility   of   using   organism
toxification-detoxification     concepts      for     the
development of site-specific criteria, 1984.
•     Field  validation of  protocols for derivation of
site-specific water quality criteria,  1984.
•     Development of protocols for modifying national
water quality criteria for marine waters, 1984.

Issue: How can wasteload allocation techniques be used
to translate applicable water quality standards into
allowable pollution discharge loads?

      For a  pollution  discharge permit to be  issued,
Total   Maximum  Daily  Loads   (TMDLs)  must   be
developed  to  determine  what pollutant   levels   will
support  the  designated  uses.   A wasteload allocation
(WLA) procedure then allocates the allowable pollution
load  among dischargers.    The WLA  process, which
considers both point- and non-point sources  of pollution,
must  ensure  that adequate  margins  of  safety  are
incorporated into the control methods.  At  present, the
WLA  process generally works by applying the results of
mathematical models to  allocating wasteloads.

      A series  of WLA models  is being developed  and
evaluated.  They will range in complexity and scale of
application   from  simple,  steady-state,   basin-scale
screening  models  to dynamic  models that  predict
transport and fate, as well as environmental exposure,
for both conventional pollutants and potentially toxic
chemicals.   Many models  are   available  for  WLA
analyses but most have not been field-validated.

      Model users  need  information on the precision,
reliability and  applicability of  each technique, in order
to match appropriate models to site-specific problems.
They  also  need  descriptions   of  the  key  chemical,
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                    Water Quality
physical  and  biological variables that  influence  the
pollutants; characterizations of  the  ecosystem at  risk
and the  wastes to be  discharged  to it; and  a  better
understanding  of   the  relationship  between specific
discharge limit parameters  and actual impacts on site-
specific  water  uses.   In  addition, each model   will
require a  clearly  written  users'  guide  to  facilitate
effective use by the states.

     EPA's research program will focus in  the short
term (one  to  two  years)  on:   manual  and  data-base
generation, development  of WLA technical  guidance,
expanded user assistance through the Center  for Water
Quality  Modeling,  improvement  in  organic   pollutant
transformation and transport kinetics (particularly  bio-
oxidation   and    benthic   sedirnent-water    column
interactions) the linkages  to effects measures/models
for factoring in risk, and  testing of these  models in
mesocosms  and field  situations to  assess utility  and
reliability.  For the  intermediate term (two to three
years),  the  program  will  focus  on  metals  process
research and use of geochemical models for  WLA,  and
on  improved  ability  to handle  nutrients and  carbon
(conventional  pollutants).   The need for a longer term
(four or  more years) effort is  being evaluated.  Such a
program would be designed  to  produce more meaningful
WLA   techniques   for  different  metal  species,   to
assemble the  appropriate technology to assess benefits
and  costs  of  WLA  strategies  in  complex, multiple
discharge  situations, and   to  relate complex effluent
parameters to impacts on water uses.

     In  addition,  EPA research will develop and  test
biomonitoring and  bioassay field techniques  for WLA
screening,  ecosystem  response characterization,  and
bioaccumulation   and   persistence   evaluation   of
chemicals.  Similarly, research will continue  to develop
and test the sensitivity, cost  effectiveness and utility
of  chemical measurement  techniques to characterize
wasteloads  and receiving  waters for  WLA   purposes.
Results will include upgraded and evaluated models and
supporting    analytical    techniques    to    predict
concentrations   of   toxic   organics,   metals   and
conventional    pollutants    (e.g.,   oxygen-demanding
substances,  nutrients)  likely  to  occur  in  waters
subjected to different  total maximum  daily  loads  and
candidate   wasteload   allocations.      Furthermore,
techniques   will   be   developed   to   link   these
concentrations with probable impacts and, therefore, to
various "use designations."

      Planned  research results  relating to  wasteload
allocation  include:

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                    Water Quality
•     Development  and  compilation  of environmental
process rate coefficients  and related data  bases  for
application in wasteload allocation, 1984.
•     Development   and   field  testing  of  a  generic
toxicity  protocol  for  toxicity  wasteload  allocation,
based on effluent bioassays, 1985.
•     Production of  a set of models that address toxic
organics, metals and other pollutants to determine total
maximum daily loads and wasteload allocations ranging
from   current   steady-state   model   to   model(s)
facilitating   time   variant  exposure   and   loading
variability, 1983-1986.

Issue:  What is the best way to assess the impacts of the
ocean disposal of wastes?

      The disposal of wastes into oceans, estuaries and
coastal waters is either severely restricted or  tightly
regulated.  Future public policy may result in decisions
which will be based on predictions about the ecological
consequences of proposed  ocean  outfalls  and ocean
dumpings.  EPA has  embarked upon a research program
to better predict the hazards of disposal  of wastes  at
ocean sites.  The Agency will conduct this research in
coordination  with  the U.S.   Army  Corps of Engineers,
USGS, NOAA and the U.S.  Fish and Wildlife Service.

      Ocean outfall research focuses on the relationship
between effluent  characteristics and the  quality  of
receiving waters.  Major areas of investigation include
models  to describe ecosystem   assimilative  capacity,
interactions  between contaminants  in waste mixtures,
field  validation of  effluent  toxicity  tests,  and the
effectiveness of different effluent treatment processes
in reducing environmental impacts.

      Models of assimilative capacity can reveal factors
which can limit degradation and irreparable harm to  an
ecosystem.  One existing model predicts the changes in
number of species,  biomass and abundance  of  benthic
invertebrates along  different pollution gradients.  The
model is based on the concept that benthic succession is
a function of the organic enrichment of sediment.  It
can be used  to predict environmental changes  at such
sites as sewage outfalls and pulp mill waste discharge
pipes.  There is another  available model which  uses  an
index  to quantify  the  benthic succession  changes.
EPA's  research will  extend existing models  or  develop
new  ones to determine  the impact  of waste materials
on fish and other marine  life.   Researchers will also
seek  to  discriminate among  the effects  of different
materials in discharges,  including organic and chemical
contaminants and nutrients.
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                    Water Quality
     Interactions between waste substances will be the
subject of similar research.   Such interactions  may
determine  the   gross   toxicity  of  the  discharges.
Researchers   will  identify  the  contaminants   with
interactions that pose the  greatest  ecological threat.
The  results of these studies are expected to indicate
treatment  options that will be  most effective  in the
control of toxic waste disposal impacts.

     Field validations of  the effects  of  ocean waste
discharges have rarely been attempted in the past.  One
validation method involves  the application of bioassays
to sediment samples collected  at increasing distances
from an outfall  pipe.   The bioassay results  can  be
compared to the structure of the benthic community.
Research will be continued  to verify effluent toxicity
estimates with field studies.

     The effectiveness of different effluent treatment
processes  will  be   investigated  as  well.    Sewage
treatment  to modify  the levels and forms of nutrients,
BOD,  pH, suspended solids, priority  pollutants,  and
coliform content has seldom been evaluated in relation
to the impact of the treatment  process on the marine
environment.  Studies will  determine the  toxicological
properties  of  municipal wastes  that have received a
variety  of  primary, secondary  and non-conventional
wastewater treatment.  Toxicity to benthic  organisms
will  be  determined  by  adding  particulates  from the
different treatment  processes to unpolluted reference
sediments.  To determine toxicity to the pelagic biota,
effluents at environmentally relevant concentrations
will  be added to ecosystem simulators.

      Ocean dumping research will develop and verify
procedures  to better assess impacts  associated  with
disposal  of municipal sewage sludge, dredged material
and  certain industrial wastes in the ocean.  Research
will   focus   on   dumpsite  characterization,  waste
characterization,  exposure and  effects assessments to
determine the  likelihood   of  hazard, and  dumpsite
monitoring.

      Dumpsite characterization research will describe
the  physical, chemical and  biological features of a site
to the degree necessary for input into  models that may
predict  the  transport  of  wastes and the  subsequent
exposure of marine life.

      Waste  characterization studies  will  investigate
categories of  waste eligible for possible ocean disposal.
The hazard  potential  of  each type  of  waste varies
according  to  dispersion characteristics, chemical and
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                    Water Quality


toxic  properties,  persistence  and  the  presence  of
residue-forming contaminants.

     The exposure  assessment research will develop
models  that   accurately   replicate  ocean   disposal
conditions.  EPA  will develop  a  hierarchy of models
organized by temporal and  spatial resolutions required
for  disposal   decisions,   and  by   needed   type  of
information (e.g., water, sediment  or biota).

     To assess the  effects of ocean disposal,  short-
term   screening  methods   and long-term  predictive
methods  will  be  developed.    Verification of  the
biological results is  expected to be the  most complex
part of this research, and  will therefore receive the
most attention.

     Procedures  to  monitor  dumpsites  for  long-term
effects will be developed to aid in determining whether
a  dumpsite location  should  be  discontinued  or  the
dumping  of   certain  wastes  should   be   limited.
Monitoring  data  will  also be used  to verify  the
predictions resulting from hazard assessment protocols.

     Planned  research products include:

•    Methods Manual for conducting sediment toxicity
surveys near ocean outfalls, 1983.
•    Reports  on persistence and  fate of pollutants in
marine food  webs,  1985,  and report   on   discharge
conditions  at  ocean  outfalls  necessary to protect
marine ecosystems, 1986.
•    Hazard  assessment protocols to permit  a  better
evaluation of the impacts of ocean dumping, 1986.
•    Procedures to monitor dumpsites for chronic long-
term effects,  1985, and
•    Dumpsite   selection    protocols   to    identify
appropriate dumpsites for a selected waste to  minimize
the impact of  ocean  dumping,  1986.

Issue:  What are the dynamics and biological availability
of pollutants in sediments?

     Sediments  are  the  ultimate  sink   for   most
pollutants  in  marine,  estuarine and lake ecosystems.
Consequently, pollution concentrations in sediments are
generally many times  greater than those in the water
column.  For most pollutants, the amount   found in
sediment contaminants represents a  sizable portion of
the total pollutant load.  For hydrophobic compounds,
sediments contain the majority of the load.   Thus, to
understand  fully  the  fate   and  effects   of  toxic
compounds in  aquatic  ecosystems, comprehensive data
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                    Water Quality
are needed about  the  dynamics and  bio-availability
pollutants in the sediment reservoir.

     The emphasis of  current  EPA  research  is  on
sediments of oceans  and estuaries.  The  research  will
seek to: develop models of  the  transport and fate of
pollutants, determine  the  bioavailability  of  sediment-
associated pollutants to benthic organisms,  determine
the  availability of  sediment-associated pollutants to
pelagic  organisms,  and  measure rates  and  factors
regulating pollutant degradation.

     Research on  the physical  transport and fate of
particles will  be used to validate predictions of area-
wide  impacts  of  dredge  spoil  disposal  and sewage
discharges.      Research   will   also  improve   the
understanding of the effects  of variable current speeds,
vertical density profiles, settlement rates  and physical-
chemical interactions.  Based on results of sensitivity
analyses, it should be possible to provide more effective
monitoring   to  determine   impacts.     Laboratory
experiments  will  identify   the  factors controlling
particle  aggregation  and   disaggregation  and  their
influence on  settlement rates.  Other experiments  will
assess  the impact of filter-feeders on the settlement of
various types of particulates.

     As the aqueous-to-solid phase partitioning is a
function of the type  of particle (e.g., clays, humics,
etc.),  it  is  necessary  to  determine  the  frequency
distribution of  particle types in  natural waters  and to
determine the  sorption isotherms  for the   dominant
particle  types.  Combining  laboratory  and  field data
with suitable sediment transport models will generate
predictions of the distribution of nearly all pollutants.

     The research to determine the factors  regulating
bioavailability  of sediment-associated  contaminants to
benthic  organisms is  being  approached in two  ways.
First, through the continued development and testing of
selective extraction techniques.  And, second, through
the determination of equilibrium sorption isotherms for
the  various  geochemical  phases  of  sediments (e.g.,
clays,  humics, bacteria, etc.) and for the bioavailability
of the contaminants associated with each phase.  With
this  information, it should  be possible to predict  in the
laboratory  the   bioavailability   to  ecosystems   of
contaminant-spiked   sediments  and,   eventually,  of
natural sediments  of known phase composition.

     Perhaps  the  dominant  research question  to be
answered concerning the sediment reservoir is whether
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                    Water Quality
the  contaminants,  such  as metals  and  non-volatile
organics,  are  "trapped" or  whether they  re-enter the
pelagic food   webs,   potentially  leading  to  human
consumption.   One  possible  transfer  mechanism to
pelagic food webs is the direct or indirect consumption
of contaminated benthos  by  fishes.   Studies  of the
importance   of  trophic    transfer  have   generated
conflicting  results;   in   some   cases   ingestion  of
contaminated   prey  is the dominant  uptake  route,
whereas  in other  studies  trophic transfer  makes  a
trivial contribution  to bioaccumulation.

      A promising  research  approach to the study of
trophic transfer  to  fish  is to relate the  uptake of
pollutants  from  food and  water  to  the  bioenergetic
requirements of the fish.  The  advantage of developing
and  verifying  this  model  is that  it may be used  with
adsorption data to predict the  importance of different
uptake routes for different  species and contaminants.
The  utility and critical assumptions of this model will
be tested  on a variety of benthic species and fishes in
the  laboratory.    Field   verification  will  compare
predicted  versus  actual body burdens at several trophic
levels by using several of the pollutant tracers.

      Other  tests of   the  bioaccumulation model  will
look at reciprocal transfers of benthic organisms from
clean  and contaminated  sites to predict uptake and
depuration rates. The mussel Mytilus sp.  will  be  used
as the test filter-feeder.

      Finally,  studies  will be undertaken to  determine
the  importance  of   degradation, resuspension  and
sediment-water fluxes in  controlling the distribution of
contaminants.  The  effects of biological activity on
these pollutant fluxes and, conversely,  the  effects of
pollution on the  rate  of biological activity need to be
studied.   These  studies  will be  done with  controlled
experiments in microcosms and flumes as well as in the
field.  Results will be useful as input parameters to the
fate and bioaccumulation  models and as a guide to the
management of contaminated sediment.

      The  same questions about sediment  contaminant
effects in  marine water  also   apply  to freshwater
environments.    Many toxic materials  are  bound to
suspended  solids and eventually  concentrate  in the
sediments of lakes and streams. EPA scientists seek to
determine  whether   these  sediment   contaminants
adversely  affect  aquatic  ecosystems or  whether the
sediments  become  a long-term  repository  for  toxic
substances.
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     Research on the  biological effects of freshwater
sediment contaminants is  needed to determine whether
acute or chronic toxicity is  caused  by toxic material
associated  with sediment, to  determine whether  the
sediments   are  a   source   of   contaminants   for
bioaccumulation  to  levels  of  concern  for  human
consumption,  and  to  develop laboratory methods  for
assessing    or   predicting   effects    of   sediment
contaminants.  Current EPA  research addresses  two of
these areas.   The role of sediment  contaminants in
acute toxicity is being examined through a combination
of field and laboratory studies, and  methods are being
developed  to  assess  the  acute  effects of sediment
contaminants.

     Planned  research results include:

o    Determination  of  the  biological  effects   of
contaminated   sediments  at   field   sites  and   an
assessment of  the need for sediment criteria, 1983.
o    Improved process descriptions for mass transfer
and biokinetics of toxic chemicals between the  bottom
sediments and water column in aquatic systems,  1985.

Issue: What analytical test procedures and quality
control  methods are necessary for accurate measurement
of habitat?  What monitoring is  needed to quantify water
pollutants?

     Habitat  is a dynamic, site-specific combination of
physical,  chemical and biological components.   The
design  of  a site-specific  management  program for a
particular water use will  depend on  a  determination of
the  state  of  these  components and  the  means to
monitor their  interactions.  In  the absence of a means
to monitor water body dynamics and interactions in the
water and sediment, it is  difficult to adequately define
the integrity of a waterway.

      One of the key monitoring problems is the  need to
identify waterborne organic  compounds and classes of
compounds.   At present, the  ability  to  identify  and
quantify  concentrations   of  organic  compounds  is
limited, and monitoring methods with quality assurance
support are even more limited.  Subcellular biochemical
mechanisms offer a potential monitoring tool that can
explain the interactions  of  mixtures  of pollutants at
particular sites.  These biological mechanisms may also
become  screens  for   measuring   attainment   or
maintenance of a particular  use by a water  body.  One
such mechanism is toxicity — a bioassay which has been
standardized  to  a  degree.   Other  bioassay  procedures
need to be standardized so that comparable data can be
gathered among site-specific investigations.

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                    Water Quality
     EPA   will   provide   standardized   analytical
monitoring methods as well as quality assurance for the
adequate performance of biological, chemical, physical
assays  and  the  monitoring  of ambient  water quality.
EPA's  efforts include cooperative activities with the
American Society of  Testing Materials (ASTM) and the
U.S. Bureau of Standards.  The research should include
the  use of  subcellular  biochemical  systems,  more
sensitive chemical analysis, and  the  development of
protocols for site-specific assays of habitat.

     Monitoring of the organic and inorganic pollutants
at a water  site is limited because  at present only about
250  chemical   and  physical  parameters  have  been
identified for monitoring under  the technology-based
regulation  of  wastewater discharges.    Thousands of
compounds, most  of  which have  not  been  identified,
have been detected by gas chromatographic and mass-
spectrometer  (GC-MS) analytical  techniques.   These
compounds  represent  only  about  one-half of  all the
organic  compounds   present   in   tested   waters,  as
estimated from  measures of total  organic carbon. Less
is  known  about the  nature of  the other half of the
organic compounds loading  wastewaters and receiving
waters.  Efforts are  needed to improve our knowledge
of the interactions of these  organic  compounds with
inorganic   chemical  moieties,  especially  within the
context  of  the  wasteload  allocation  and  criteria
modification processes.

     EPA  will develop analytical methods and quality
assurance  for  the  measurement  of  the  chemical
pollutants   and   environmental   adducts   of   those
pollutants.   Included in the research will be the  organic
and  inorganic materials  which have been detected in
discharges but which are  not presently monitored.

     Planned  monitoring results include:

•    Monitoring  methods   for  measuring  priority
pollutants in sludges,  1984.
•    Risk assessment methodology for assessing multi-
media risk for a  variety of disposal options, 1984-1985.
•    Combination  of   industrial   survey   and  field
monitoring  of effluents  to  characterize variability in
ten  major   industrial  discharges,  in order to develop
relationships between effluents and  water use impacts,
1985.
•    Chemical  methods  to  measure  toxic forms of
metals, 1985.
•    Design,  based on existing data and hydrological

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                    Water Quality
science, of sampling protocols that provide  for  better
characterization  of  chemical  water  quality   given
variation in natural flow and effluent variability,  1986.
•    Laboratory  test methods and  data interpretation
methodology   to   permit  estimate  of  risk  to the
biological  organism  from  intermittent,  fluctuating
exposure, 1986.
•    Reliable, inexpensive methods for analyzing toxic
pollutants, 1986.

Issue: What are the key technical and scientific factors
that limit the effective treatment and use of sludges
from wastewater  treatment?

     The  costs  for  sludge  treatment  and  disposal
represent  a  major portion  of  the  overall  cost  of
wastewater treatment.   Moreover, the  potential  for
environmental impacts from  the disposal of sludge is
significant. Consequently, research is needed to define
optimal sludge use or disposal options.

     The methods  to assess sludge disposal options will
be refined, with  research developing both  methods to
determine ecosystem  resiliency  or stresses  resulting
from disposal of sludges and methods to  predict  the
human health effects from sludge exposures. The latter
could include bioassays or other  toxicity  tests for both
health and ecosystems.  Other  research  is needed to
develop   ways   to  mitigate  risks  through  sludge
treatment or  disposal.   Such  research will include
analysis  of the  cost vs.  performance  of engineering
designs for various  treatment and disposal,options.

     Other sludge-related research is need to provide
an  improved  understanding  of  the sources of  heavy
metals,    toxic   organic    compounds   and   other
objectionable constituents in  municipal wastewaters, to
develop epidemiological data  on  the use of processes to
inactivate organisms  and  viruses  in sludges,  and  to
improve   risk assessment  methods for   decisions  on
alternative means of sludge management.

      In developing needed fundamental data about new
processes  for improved sludge stabilization, reduction,
energy  recovery  and  use  the research  program  will
assess integrated disposal options.  The  major planned
products of this research include:

•    Design   guidelines    on     sludge   treatment
technologies, with  cost  and  performance  data, that
focus   on   innovative   anaerobic  sludge   digestion
processes, energy  recovery, pathogen  reduction,  and
more efficient thermal conversion processes, 1986.

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                    Water Quality
•     Feasibility  report  on  the  use  of  genetically
engineered  methagenic  bacteria  for  improving  the
reliability   and  increasing   the  rate  of  anaerobic
digestion, 1985.

Issue:  Are occurrences of infectious diseases increased
by certain sludge disposal practices?

      The land application of sludge will be studied to
determine  the effects of this  disposal option  on the
incidence  of  human  infectious  disease.   EPA is
encouraged by the  potential of  this  disposal method
because it recycles  nutrients, conditions the soils, and
may help  to  limit  waterway contamination.   Health
studies will  determine  whether  land  disposal  can
proceed without increasing health risks.

      Epidemiological  studies  have  been  initiated to
evaluate health hazards.  Results  from these  studies
will provide data that can  be  used to determine the
effect  of  various   pretreatments  and   application
techniques upon disease occurrence.

      Studies on the  survival  and transport of pathogens
will be continued. Virulent enteric viruses that occur in
domestic   wastes  have  considerable environmental
survival  potential.   These  viruses  can be  transferred
directly to  people or  transported from waste-amended
soils to surface or ground waters used for  recreation or
drinking water.  Roundworms (Ascaris) have also been
identified as a pathogen of  concern in sludge because
the  ova  stage of  this  parasite  is  believed  to  be
extremely   resistant  to  environmental   degradation.
However, definitive data on its survival is lacking.

      Carefully controlled field studies are continuing
to  define  the survival  and  transport limits  of  the
disease-causing organisms.   These  field data, coupled
with epidemiological data on exposed  populations, will
provide assistance  in  making sound judgments  on the
limits of recycling of domestic wastes.

      Major planned products of  this research include:

•     Water quality  health  criteria for fresh  water in
recreational use, 1983.
•     Bioassay    testing   methods   to   assess   the
effectiveness   of   alternative   wastewater    control
technologies, 1985.
•     An  assessment  of  EPA's epidemiological data,
1986.

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  Chapter Three
DRINKING WATER

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                   Drinking Water
DRINKING WATER
Outline:
Introduction
Background
Legislative Mandate
Major Research Issues
     Issue:   What data and  methods are necessary to
     improve the extrapolation of toxicological data on
     potential carcinogens in drinking water?
     Issue:   Do organic  by-products from chlorination
     pose  health  risks?   What methods can control
     these by-products?  Are alternative disinfectants
     safer?
     Issue:    What water  treatment technologies are
     applicable to small communities?
     Issue:   What new methods are needed to analyze
     organic contaminants?
     Issue:  How should quality  assurance requirements
     be incorporated into the compliance program?
     Issue:    Are  geophysical  monitoring techniques
     applicable to drinking water problems?
     Issue:    Does  subsurface  biotransformation  of
     pollutants  help to protect  underground sources of
     drinking water?

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                   Drinking Water
INTRODUCTION

     State  and  local  governments  have  the  main
responsibility  for drinking water quality.   A  growing
population is  increasing demands on the water supply
while,  at  the same time, chemical  contamination of
water   sources   appears   to  be  increasing.  Water
management  decisions   are  becoming  both  more
complicated and more difficult.

     State governments need help  in addressing major
problems related to drinking water quality.  In a list of
state/EPA  agreements,  support  for  drinking water
responsibilities emerged  as  the major  EPA research
function  requested  by  state  governments.    State
government decision makers are especially  concerned
about  revisions  of  the  National  Interim  Primary
Drinking  Water  Regulations (NIPDWR) due  in  1984-
1985, when new  regulations  for a variety  of synthetic
and volatile organic chemicals will also be considered.

     Additional scientific data are  also needed as input
into new  regulations.   For example, disinfectants  and
disinfectant  by-products, as well  as safe alternative
disinfectants, must be evaluated.

BACKGROUND

     The  primary goal of this EPA  research  program is
to develop the scientific  and technical data needed to
assure safe public drinking water systems.  Much of the
drinking water research program is  designed  to provide
information to state and local water authorities and to
develop the information needed  for  changes to  drinking
water  regulations.  The three major components of the
program are: research to support implementation of the
EPA drinking water regulatory  program, protection of
ground-water   resources,  and  development  of   the
scientific    basis   for    state   implementation   and
compliance programs.

     In health  research, the primary purpose is  the
development  of  information on  the  toxicology  and
human  health   risks   associated   with    substances
commonly found  in  drinking   water.    Other major
aspects of  the health  research   program are  the
development  of  chemical  analytical  methods  for
determining   the  identity   and   concentration   of
contaminants, and the  assessment  of technologies for
controlling such substances.

     The  drinking  water research program for  fiscal
year 1983 is allocated  $23.3 million.  These resources
are  distributed  among  the  research  disciplines  as

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                   Drinking Water
follows:   health   effects,   39%;   engineering  and
technology,  32%; environmental processes and effects,
20%; monitoring systems and quality assurance, 8%; and
scientific assessment, 1%.

LEGISLATIVE MANDATE

     The Safe  Drinking Water  Act (SDWA),  P.L. 93-
523, as amended, requires EPA to establish drinking
water regulations to protect human health and welfare.
The  NIPDWR regulations fulfill that  requirement  by
specifying    maximum    chemical   and    biological
contaminant levels (MCL) allowable in drinking water.

     Another EPA drinking water role, described in a
memorandum of understanding with the Food and  Drug
Administration,   defines  EPA's  responsibilities  with
respect to drinking water additives.

     The Safe Drinking Water Act also grants EPA the
responsibility and authority to  conduct drinking water
research.   Section [Ift2  of the  SDWA  specifically
authorizes EPA to engage in research concerning:  the
occurrence   and  health   effects  of  chemical   and
biological   contaminants   in   drinking  water,   the
analytical procedures for monitoring contaminants, the
applicability  of treatment technologies, the protection
of  underground   drinking  water   sources   and   the
exploration   of   scientific   questions  for  emerging
problems.

MAJOR RESEARCH ISSUES

     As EPA satisfies the specific requirements of the
SDWA and implements safe  drinking water  programs,
the drinking water research  and development program
becomes    focused    on    specific    programmatic
considerations,  monitoring,  and  new  problems  that
become apparent.   This orientation  of  the program
produces data about: low-cost,  innovative technologies
to supply drinking water; control of toxic organic and
inorganic chemicals; the  methods  to  detect, measure
and  monitor  precise  contaminant  concentrations  in
water;  techniques to describe toxicity of contaminants;
and  specific information about organic contaminants,
disinfection  by-products,  additives, corrosion problems
and  compliance problems.   The  research  will  also
expand   our   fundamental   knowledge    of    basic
environmental  processes  and   drinking  water  health
impacts.

      The major  drinking water research issues in this
Research Outlook  reflect both this problem-solving
orientation and the need for monitoring data to  support

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                   Drinking Water
proposed NIPDWR changes.  The issues addressed in this
chapter are:

o     What data and methods are necessary to improve
the  extrapolation of  toxicological  data on  potential
carcinogens in drinking water?
o     Do   organic  by-products   from   chlorination
disinfectants pose  health  risks?   What  methods can
control   these   by-products?      Are   alternative
disinfectants safer?
o     What water treatment technologies are applicable
to small communities?
o     What new methods are needed to analyze organic
contaminants?
o     How  should quality  assurance  requirements be
incorporated into the compliance program?
o     Are geophysical  monitoring techniques applicable
to drinking water problems?
o     Does subsurface biotransformation of pollutants
help to protect underground sources of drinking water?

Issue:  What data and methods are necessary to improve
the extrapolation of toxicological data on potential
carcinogens in drinking water?

      The issue stated above is  generic in that it applies
to all activities involving assessing the carcinogenicity
of chemicals in the environment.  At the same time, it
specifically applies to drinking  water because a number
of  chemicals identified as common  contaminants of
drinking water have been shown to  be carcinogenic  in
some animals.

      Many efforts to quantify  the health risks of  these
chemicals  have  been  based  on  the "no  threshold"
assumption  that  very  low doses of  the chemicals can
alter genetic material and have a carcinogenic effect.
Nevertheless, if  a chemical produces cancer  without
direct interaction with the genetic  material, that is,
through  a non-genotoxic mechanism,  there  would be
some  question  as  to  whether   this   no-threshold
assumption is appropriate.  EPA is currently evaluating
both of the possible mechanisms — genotoxic  and  non-
genotoxic — which  may produce cancer,  in  order to
develop  appropriate  extrapolation  models   for  the
chemicals found  in drinking water.   The key  research
question is, what experimental data are necessary to
differentiate  between  chemicals which  may act as
tumor   initiators   (which  are   usually   genotoxic
carcinogens)  and  tumor  promoters  (non-genotoxic
carcinogens)?

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                   Drinking Water
     EPA  shares interest  and  information  in  this
research issue with other federal regulatory agencies —
primarily the Food and Drug Administration (FDA), the
Occupational Safety  and Health Administration (OSHA)
and the Consumer Product Safety  Commission (CPSC).
FDA has a substantial research program involving  oral
exposures.    OSHA's  interest  is   primarily  in  the
inhalation route.  Other federal research agencies are
studying the mechanisms of  chemical  carcinogenesis
but  the objectives   of the  various  basic  research
programs generally  do not  emphasize the  critical
problem  of risk  assessment, which  is of major concern
to EPA and the other regulatory agencies.

     The work   that  EPA  will  carry out  has  two
objectives:   to  establish the  criteria for  determining
whether  a  chemical is acting by  a tumor-initiating
versus  a tumor-promoting  mechanism  in a particular
target  organ, and to  establish which chemicals shown to
be carcinogenic  and  of  frequent occurrence in drinking
water  should be treated  as  tumor  promoters   for
purposes of quantitatively estimating their risk.

     EPA has helped to develop an  initiation/promotion
assay model in the rat  liver and is extending  the work
to  mice.    Use  of  these  animal  models  plus  the
application   of    biochemical  methods   to   assess
interactions  of   chemicals  with   DNA will  help to
improve  evaluations  of the  relationship  between  a
chemical's genotoxic activity and its  ability to produce
cancer, and will  enable researchers to develop measures
of  tumor-promoting  activity.   Chemicals known to
promote or initiate tumors will be used to validate the
ability   of   different  parameters  to  differentiate
accurately   between  genotoxic   and   non-genotoxic
carcinogens.   The results of this research will help to
determine the most  appropriate  model  for  different
chemicals in  risk assessments and, further, will improve
our understanding of, the implications of extrapolating
from high to low dose.

     This research  approach may be  useful because,
with the rat and mouse models, cell changes occur at
frequencies  much higher than  do  tumors.   This  means
that  EPA  could  develop  interspecies  extrapolation
models for  both  cancer-producing mechanisms using
relatively small  experimental groups at a considerable
savings compared to  conventional lifetime experiments.

     Currently, the  major scientific information gaps
are the  lack  of adequate criteria to  identify clearly
chemicals    that    act   through   tumor-promoting
mechanisms, the lack of information concerning tumor-
promoting activity of chemicals identified  as  common

                         50

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                   Drinking Water
contaminants  of  drinking  water, and  the lack of  an
adequate  methodology  to  assess the  health  risk from
exposure to these chemicals.

     EPA's research  in  1983  and  1984 will  further
refine  the models  based  on the findings of the liver
tumor  studies  in  rats  and mice.   In 1984  and  1985,
experimental data  will be  developed to classify liver
carcinogens in drinking water  that  are likely to cause
health  effects.  By 4985, EPA research will  produce a
theoretical  basis  for  differentiating between  a non-
threshold   and  a  threshold  mechanism  of   tumor
induction.   A model   will be  developed to estimate
health  risk from the threshold mechanism.  Research in
1985 and beyond will validate extrapolation models used
to arrive at acceptable levels of chemicals in drinking
water.  This work  will  focus on development of  systems
to validate interspecies extrapolation  through  the  use
of primary in  vitro cultures of human tissues as well as
appropriate animal tissues.

Issue:  Do organic by-products from chlorination pose
health  risks? What methods can control these by-
products?  Are alternative disinfectants safer?

     It is known that drinking water disinfectants react
with the organic material in source waters to produce a
variety   of    by-products.      The   formation   of
trihalomethanes in drinking water is a well documented
example of such  a reaction.   Chlorinated water  has
been found to possess mutagenic activity measurable in
the Ames  Salmonella  assay.  It is  also known that a
great  many other  products of chlorination besides  the
trihalomethanes  have  the  ability  to  alter  genetic
structure.  EPA research has made  major contributions
in this  area.

     The  fact   that   some  chemical  compounds,
suspected  to  be  carcinogenic,  are  formed  during
chlorination of drinking water creates  a dilemma.  It is
important  to limit human contact  with cancer-causing
agents but it  is also essential to use water  treatment
techniques which  keep waterborne  infections at their
current low levels. However, there  is still no indication
that  any  alternative  treatment   to  chlorination   is
significantly safer.  The relative  hazards  associated
with the use of each of the disinfectants and their by-
products have  yet to be determined.  To build the data
base needed to arrive  at the safest possible means of
disinfection,  researchers  will  have  to  consider  the
toxicity of the disinfectants and their by-products, the
efficacy of each disinfectant in preventing transmission
of waterborne  infectious disease, and the best methods
to control contamination.
                          51

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                   Drinking Water
     EPA  research has identified  the extent of  the
trihalomethane contamination  problem and, in concert
with  universities   and  water  utilities,   has   also
determined  the effectiveness  of  various  methods  to
control  trihalomethanes in water.   The  approach  to
controlling  trihalomethanes (THMs) is four  pronged:
removal of these compounds by treatment, removal of
their  precursors  by  treatment,  reduction   of  their
subsequent formation by use oi alternate disinfectants,
and  changing  the  point  at  which disinfectants  are
applied.   The  emphasis  of this approach is on  the
prevention of trihalomethane formation.  Utilities are
continuing to study  the techniques most appropriate to
control  trihalomethanes,  which  are  now  regulated.
There is still,  however, a lack of clear understanding
about  the  fundamental  nature  and  extent  of  the
chemical reactions that cause  the problem in the first
place and about the health effects and risks that come
from the by-products.

     Chlorination   of    drinking   water   produces
mutagenic  activity  in   test   systems.     Yet  the
trihalomethanes and other specifically identified by-
products of chlorination  account for less  than 2% of
mutagenic activity of  the chlorinated products and by-
products of chlorination.  Some compounds have been
confirmed    as    carcinogenic.       For    example,
haloacetonitriles    identified    as    by-products   of
chlorination  have  had  their  carcinogenic  activity
confirmed in mouse skin initiation/promotion studies.

     Alternative    disinfectants  to chlorine are also
reactive chemicals and give rise to as yet unidentified
by-products that also possess mutagenic activity.  Their
supposed   carcinogenic   activity   remains   to   be
confirmed.   Consequently, no  firm conclusion can be
drawn  as to which  disinfectant method is safest.  To
support a choice among the alternatives, data are being
developed to establish: the relative hazards  associated
with the use of each of the disinfectants  and their by-
products   the   efficacy  of   each   disinfectant  for
controlling  waterborne  infectious agents and  whether
any single one is effective against all biological forms.

      By  1985,  for  example,  information  will  be
available on disinfection practices.  EPA investigators
have been evaluating these processes in laboratory and
field tests.    Other  research will characterize  and
improve treatment technologies including  disinfection,
microbe filtration,  ion exchange, aeration, adsorption,
and/or  reverse osmosis for  the control of  organic,
inorganic  and  radionuclide   chemicals,   chlorinated
organics and/or particulates.  Pilot programs are used
to assess cost effectiveness and feasibility.

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                    Drinking Water
      EPA  research  is  attempting  to  identify  the
specific  characteristics, extent and health significance
of reaction by-products.   Laboratory work will define
the  extent and  character of  reactions  with  aquatic
humic materials and the nature of organic halogen and
oxidation by-products that are formed.  The physical
and  chemical factors that influence the  reaction also
will   be   identified  as  the   first  step   toward  the
development  of  control   strategies  which  may  be
warranted by health effects data.

      Laboratory work to characterize the  compounds is
now  under way.   Preliminary  treatment data focusing
on the amount  of organic halogen  produced is  being
collected  from  bench  and pilot studies. Treatment
method  effectiveness  data will  be  developed  later.
Should the health effects research indicate a health
problem,   evaluations  will be  made  at  full-scale
treatment plants.

      Research on health  effects will  be  conducted in
parallel   with   the  research  to   characterize   the
compounds.  EPA has already undertaken the primary
role  to determine overall  health hazards  from  the use
of each alternative disinfectant. A companion research
effort is  being conducted by  the  National Toxicology
Program to test several individual disinfectants and by-
products in lifetime carcinogenesis bioassays. Related
health research  includes:   the  demonstration of similar
biological  effects  in   samples   concentrated  from
drinking   water,   the  analytical  demonstration   of
parallels   between  products   formed  under   model
conditions and those formed in actual situations,  the
assessment of hazards  of  major  individual compounds
and  of the  toxicity of  the  disinfectants  themselves
(including the in vivo formation of toxic products).

      Evaluations  of the  toxicity of disinfectants will
use  established  techniques in  target organ toxicology
(including  reproductive  studies),  carcinogenesis  and
mutagenesis  testing.   Although preliminary  clinical
trials have been conducted with these agents in normal
human volunteers, the  toxicological properties of  the
disinfectants  indicate  a  need  to conduct studies  on
sensitive  human  populations,  e.g.,  individuals   with
compromised thyroid  function, before the  disinfectants
are actually used to treat drinking water.

      By-products  will  be evaluated using  a modified
tier  approach.    Screening methods  will  determine
whether   significant  biological activity  results  from
                         53

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                   Drinking Water
treating model substrates or actual water samples with
alternate  disinfectants.   These short-term assays will
allow fractionation and individual identification of the
toxicologically important by-products.  The fractions
found to be toxic will be tested further to  provide data
to assess actual risks.

      The   major  products  found  to  have  biological
activity will be subjected  to  comprehensive study  of
their  carcinogenic, mutagenic and  other  toxicological
properties.  In fact,  by  1986  it is expected that the
research will  have demonstrated extensive qualitative
and  quantitative  applications of  bioassay  results  to
estimate  human health risk.   This methodology will
serve as the basis  of judging hazards posed by complex
mixtures   of   chemicals  as   well   as  by   individual
compounds.

      By 1985, studies will be  made of the  toxicological
properties of  the  disinfectants and their  by-products
with  natural  background  organic  matter present  in
source waters.  By 1986, additional  studies will assess
the  effects of the  disinfectants  in  the susceptible
human volunteers.  Also  in 1986, studies will evaluate
whether  the characteristics of the source water must
also be considered when choosing a disinfectant  for use.
Methods   being   examined  include  procedures   for
quantification  of  viruses and parasites  or  improved
indicator  systems.

Issue: What water treatment technologies are applicable
to small communities?

      Many small  communities in  America  have  a
difficult  time in  meeting  the drinking water  quality-
levels set  forth   in  the  National  Interim  Primary
Drinking  Water Regulations  (NIPDWR).   In a recent
survey, the U.S. Government  Accounting  Office found
that  146,000 violations of the NIPDWR for community
water supplies had been reported.   From  the small
communities'  point of  view,  the main problems  with
complying with NIPDWR are the high cost of producing
the  small  volumes of  drinking water  used  by  the
community and the  difficulty in  hiring and retaining
trained operators for water  treatment plants.

      EPA's drinking water  research program will take a
strong  role   in   evaluating   cost-effective   central
treatment technologies.  Emphasis of the  research will
be on evaluating new technology for the ten regulated
inorganic   contaminants   three   radionuclides   the
regulated  pesticides  (endrin,  lindane, methoxychlor,
toxaphene,   2,4-D   and    2,4,5-TP   silvex),   and

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                   Drinking Water
trihalomethanes.   This research  will  also evaluate
industry   solutions  to  non-central,  or  point-of-use
treatment  for  the home as an alternative  to  central
treatment  to remove some inorganic as well as  organic
contaminants.  The purpose of this  research is  to test
the  effectiveness  of  treatment  methods  and  to
encourage  the  use of  the  best of  them.   Additional
consideration will be given  to treatment methods that
will  result in drinking water to meet different  quality
requirements.  EPA's research will also help to evaluate
new    and  improved   technologies   for  removing
unregulated inorganics, organics, microorganisms and
particulates.

     Research is  continuing to evaluate the cost and
engineering feasibility of specific treatment  techniques
to remove or control problem inorganic contaminants
(such  as  arsenic,   radium  and   uranium),   organic
contaminants  (including  pesticides  and    chlorinated
organic solvents),  trihalomethanes, microorganisms and
particles.  Several evaluations are at pilot or full scale.
Bench-scale studies are being done  to define variables
that   govern   the  effectiveness   and  efficiency  of
treatment  processes  prior  to  large-scale evaluations.
Reports of these findings will be released beginning in
1984 and continuing into 1987.

Issue:  What new methods are needed to analyze organic
contaminants?

     The trihalomethanes,  chlorinated  pesticides and
herbicides  regulated by the NIPDWR can  be detected,
measured and analyzed in drinking water using state-of-
the-art -analytical  methods.   Additionally,  analytical
methods have   been  developed  for  the  14   volatile
organic chemicals (VOCs) proposed for regulation with
maximum  contaminant  levels  for  drinking  water.
Methods have not been developed, however, for  many
non-volatile  compounds  such  as  pentachlorophenol,
dinitrophenol,   atrazine,   simazine,  picloram   and
phthalates  which are  sometimes  found in drinking
water.

     Analytical methods are not currently available for
all of  the  compounds that  might  cause problems, but
the  monitoring research will identify  the analytical
deficiencies. Research planned over the next few  years
will investigate analytical methods applicable to a large
number of chemicals, including intractable  and highly
refractory  compounds.    Analytical  methods  use
advanced   technology   to   detect   drinking   water
contaminants.   High-resolution (capillary column) gas
chromatography,   high-performance   (microcolumn)
liquid  chromatography  and  gas  chromatography/mass
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                   Drinking Water
spectrometry  methods  are  becoming  more  widely
available.   New  means  to  apply  these  analytical
methods  are being developed as well. For example, a
technique which  measures  total organic halogen is a
reasonable, less  expensive  and more  rapid  method for
analyzing halogenated VOCs.  Similarly, in the effort to
detect the  l5  VOCs proposed  for  regulation,  new
analytical   methods  have   been   developed   for
halogenated solvents  and  non-halogenated  aromatic
volatile purgeable compounds, which are indicators of
industrial contamination.

     Two  significant  approaches  are:  adsorption  of
organics  into  solid  sorbents  and subsequent  thermal
desorption  directly  into  a  gas chromatograph  or  a
chromatograph/mass  spectrometer,  and  an  extended
purge-and-trap system which, as an advanced version of
closed-loop stripping, may  apply  to  a wide  range  of
volatile chemicals.  Methods will also continue to  be
developed which use surrogate parameters as indicators
of chemicals that are difficult and expensive to detect.

     Some  of   the  chemicals   requiring   possible
analytical methods may  be identified from other EPA
research.  For example,  risk assessment  studies may
identify  chemicals  that  pose a health risk and water
technology studies may  reveal various hazardous  or
toxic chemicals  being  discharged to wastewaters  or
drinking  water sources.   The application  of  advanced
control  technologies  may  also  call  into question the
applicability of the current means to preserve samples
because  of possible chemical reactions  among the
organic contaminants  in  the samples during  storage.
The  output of the drinking water analytical  methods
research  program   is mostly  near  term  to  meet
impending deadlines of the NIPDWR review.

Issue: How should quality assurance requirements be
incorporated into the compliance program?

     Semi-annual    performance    evaluations    of
laboratories,   on-site  visits  by  testing   teams  and
distribution of updated  procedure manuals constitute
EPA's  efforts to  assure  the quality of  data  used  in
drinking  water research.   In a related  program, EPA
approves alternative test procedures for national use.

      Samples  for   quality  control  checks   and  for
performance   evaluations  to certify laboratories,  as
required by the Safe Drinking Water Act, are currently
available for  all  of the  regulated  drinking water
contaminants.    The  EPA  drinking  water   research
program   produces   the   samples,   documents  the
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                   Drinking Water
concentration levels, establishes sample shelf lives, and
distributes  them   to   laboratories  that  are  to  be
evaluated  for  performance  or  are  to  undergo  a
certification  check.    EPA  is  also responsible  for
conducting and verifying those evaluations and checks.

     To stay current,  the  research  program needs to
increase the  number  of  laboratories certified  to do
quality  analyses, particularly private  organizations that
may have to  replace  EPA's efforts.   The research
program also needs to  increase the number and types of
test parameters used in performance  evaluations and to
update  the  procedural manuals  for field  sampling,
microbiological analysis and evaluation ol' chemical and
radiochemical certification.

     The  quality  assurance  work   is  expected  to
continue  for  several years.  Performance  evaluation
studies  and the distribution of quality control samples
will occur  each  year, as will  the development of
expanded quality control sample series and  reference
standards    for    newly   regulated   contaminants.
Microbiological manuals will be  updated  in 198^ and
1987.

     Plans  in the next  few  years  call  for EPA to
modify  and amend the NIPDWR by  issuing  Maximum
Contaminant Levels (MCL) for radionuclides  in drinking
water.    The  radionuclides of  current concern  are
radium-228, radon-222 and uranium.  Thorium, which is
four times more abundant than uranium, should also be
studied   to  determine  possible  health  effects  from
exposure through drinking water. Other studies need to
develop monitoring methods that do  not rely solely on
gross alpha particle activity in order to  monitor water
supplies for radium-228, which is a beta emitter. EPA's
drinking  water   research   program   will  develop
monitoring  methods   and  evaluate   alternative  test
procedures  or methods to  determine their  precision,
accuracy  and validity.

     The  research  approach   is first  to evaluate
radionuclide monitoring methods with a single operator
and then  to validate the methods with multi-laboratory
collaborative  testing.   EPA's   researchers  will  also
produce performance  evaluation (PE) samples, which
are  used  to  assist   in  laboratory evaluation  and
laboratory  certification.     Continual   training  of
laboratory technicians and  analysts will help  assure
future data quality.

     Over  the  next  five  years, emphasis will  be on
increasing  the sensitivity,  precision,  accuracy   and
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                   Drinking Water
rapidity of the laboratory methods.  Research efforts
will also attempt to make the methods simpler and less
expensive.

Issue: Are geophysical monitoring techniques applicable
to drinking water problems?

     One of the major potential  threats  to drinking
water quality is  the contamination  of  ground water.
Such  contamination  can come  from waste injection
wells.   It was  estimated in  1979  that  about 500,000
municipal, industrial,  commercial,  agricultural,  and
domestic wells  injected fluids into  the ground and  that
at  least  5,000  new  injection  wells  were  being
constructed each year.

     Ground-water contamination  can also come from
abandoned,  poorly constructed  or poorly  maintained
hazardous waste  disposal sites.  Wastes from disposal
sites can leach  down  into the soils, migrate into the
ground water and contaminate  water being withdrawn
as drinking water.

     Monitoring   techniques  to  satisfy   legislative
requirements and to gain more knowledge about the
subsurface environment  in general  are  not  sufficiently
precise.   For  example, current  monitoring methods
cannot track fluid movements  from existing injection
wells to  verify the safety of nearby ground water.  To
rectify  this  and  other  ground-water  problems, EPA's
drinking  water  research program has begun  to search
for  existing  monitoring   technology   that   may  be
adapted.  One  such existing technology  is  geophysical
monitoring developed for mineral resource exploration.
Oil and coal companies and hard-rock mining companies
have for years used geophysical monitoring technologies
to locate promising drilling sites and ore bodies.  Other
promising    technologies    include   magnetometers,
seismographs and resistivity measurement instruments.
These  technologies  may  need to  be improved or
modified for precision, accuracy, simplicity,  speed and
reliability before they can be used to  monitor ground
water.

      Magnetometers  measure the presence of metal
objects  and  other  geomagnetic   anomalies  in  the
subsurface by emitting  electromagnetic energy  which,
when it strikes  the  metal object, either  induces  a
current in a detector coil or alters the  proton spin of
reference   material.     The  sensitivity    of   these
measurements  can  be  sufficient,  it is expected, to
locate  abandoned  well  casings  in  the  vicinity of
proposed injection wells. Seismic reflection monitoring
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                   Drinking Water
uses  mechanically or  explosive-produced subsurface
pressure waves to map underground features, including
ground-water characteristics such as depth and types of
soil  and rock.   Resistivity instruments  measure the
electrical  resistance   of   soils,   which  changes  in
proportion   to  the  amount  of  water   in  the soil.
Resistivity surveys may be  a  means  to  monitor fluid
movements  from injection wells and to track and map
contaminant plumes from waste sites.

      EPA   will  test   these  technologies  in  actual
contamination  situations.    Airborne  and   surface-
operated magnetometers will be tested in cooperation
with  the USGS  to  locate abandoned  wells.   This
research will determine the best survey  patterns to
locate well  casings based on  the sensitivity of the
instruments  and  the  magnetic   properties   of well
casings.  Resistivity and seismic  surveys will also be
conducted at existing injection  wells.

Issue:  Does subsurface biotransformation of pollutants
help to protect underground sources of drinking water?

      Knowledge  of the biotransformation of  pollutants
in  regions   of   the  earth  below  the  root-zone  is
incomplete, primarily because  systematic investigation
of the  phenomenon  was begun only a few years ago.
The  USGS  has  produced a  small  but useful body of
literature   concerning   the   biotransformations  of
industrial wastes injected into  deep disposal wells, and
petroleum    microbiologists   have    shown   that
biotransformations  can  occur   deep   within  the
subsurface   in   petroleum   reservoirs.     But  the
microbiology of organisms indigenous to more shallow
aquifers containing  potable water was ignored until
recently, probably because  many  microbiologists felt
that   these   regions  did   not    receive    enough
metabolyzable organic carbon to support life.

      Recently, some surprising results emerged from  a
three-site survey carried out by EPA and the National
Center  for  Ground-Water   Research.  The  survey
revealed high densities of microbes -- 10 to 10 per
gram of subsurface  material — in shallow water-table
aquifers and the associated  regions of the unsaturated
subsurface  environment.    Generalizing  from  these
results,  it  may  be true  that the  total biomass of
bacteria in  aquifers and associated unsaturated zones is
greater than the biomass of bacteria in the  rivers and
lakes and comparable  to the total  bacterial biomass of
surface soil.  By the end  of 1983, EPA plans to have
developed a set of methods for  describing the character
and  populations of subsurface microorganisms.
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                   Drinking Water
     The biochemical components  of  the subsurface
microbes are recognizably different from those found in
surface habitats.  Biotransformation assays reveal that
subsurface  microbes  can  degrade  several  organic
pollutants     (chlorobenzene,     toluene,     styrene,
bromodichloromethane)  that  are  also  degraded  by
surface organisms.  There is preliminary evidence from
field    studies   that   the   halogenated   aliphatic
hydrocarbons    undergo    biotransformation    under
anaerobic   conditions,   occasionally   resulting    in
extremely undesirable products  such as  vinyl chloride.
The precise environmental conditions required for these
biotransformations are, as yet, very poorly defined.

     EPA's primary research  role in this area has been
to develop techniques to sample the subsurface without
contamination from surface materials.  To this end,  the
research  will   produce   a  manual  for   non-drilling
monitoring  and  characterizing  techniques,  and  a
document assessing the state  of the art for down-hole
(in situ) sensing techniques.  Both documents will be
available  in  1984.   In  1985,  updated manuals  will be
produced for sampling and monitoring well construction
and, in 1986, a  manual on tracer  technology  will be
published.

     An  additional  EPA research  role is to develop
techniques  for  using  uncontam mated  samples   to
construct    microcosms   for    studies    on    the
biotransformation of important  organic contaminants.
Researchers  are studying  the  numbers,  metabolic
activity,  and   biochemical  characteristics  of   the
organisms  in  the same subsurface  materials used  to
construct the microcosms.   Researchers supported  by
EPA   were  the   first  to   obtain   evidence   for
biotransformation     of     halogenated      aliphatic
hydrocarbons  under  anaerobic  conditions.   On-going
work will test these findings and more precisely define
the  environmental  conditions  under  which   these
biotransformations can be expected.

     Other   major   research   organizations   are
conducting  related  research  which  is  being  closely
followed  by EPA.   USGS researchers have conducted
some   biotransformation   studies   in   support   of
comprehensive  hydrogeologic  appraisals  at  specific
waste   disposal  sites,  including  industrial  deep  well
disposal  operations,  municipal wastewater  injection
sites,  and  an  abandoned  wood-creosoting operation.
This   work   has  consisted   almost  exclusively   of
laboratory studies of organisms obtained from polluted
well waters  and,  for the most  part, has  not been
concerned  with  aquifers  containing  potable  water.


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                   Drinking Water
Recently initiated projects, however, include studies of
hazardous wastes in drinking water aquifers. Additional
related work has been done by Swiss researchers who
have  studied  the  fate in  aquifers of  a  number  of
important   ground-water   contaminants,    including
trichloroethylene and several chlorinated phenols.

      The major objectives of EPA's current and future
research  on  biotransformation  of  pollutants  in  the
subsurface are  to  identify  those  biological processes
that may occur in  various subsurface environments, to
determine  the  influence  of subsurface  physical  and
chemical   factors  on  biological  activity,   and  to
characterize the  biological  processes  quantitatively.
Once  this is  done,  data from the research can  be
incorporated into  solute-transport models  which,  in
turn,   can  help  in  the  selection  of  cost-effective
regulatory or  clean-up  strategies.   By  1985, it is
expected   that  the   research   will  identify  those
subsurface conditions which  determine  whether  abiotic
or biotic processes dominate  pollutant behavior.

      Laboratory microcosms are  being  used to depict
the course of  biotransformation  of  organic pollutants
under  various subsurface conditions, to determine the
effect  of  pollutant   concentration  on   the  rate  of
biotransformation under both  aerobic  and anaerobic
conditions, and to identify the  minimum concentration
of  an  organic  pollutant   that  perturbs  subsurface
microbes and changes biotransformation rates.  Work is
in progress to  evaluate the  ability of  the microcosms
which are now in use to simulate the biotransformation
processes at an  existing  waste disposal  site.   Later
studies   will   determine   requirements   for   the
extrapolation of data  from a microcosm study to actual
pollution incidents.

      A possible benefit of the  microcosm work is the
identification  of a biological characteristic that can be
used  as  an index to  predict biotransformation rates.
Such an index would greatly  reduce the cost and effort
required to project the fate of a pollutant. Potential
indices include  cell  density  by  direct  microscopic
examination, biomass  estimates based on  quantities of
cellular structural components (such as muramic  acid or
lipid  phosphates) and  estimates of metabolic  activity
(such   as   adenosine   triphosphate    content    or
dehydrogenase  activity).  Preliminary  results indicate
that this approach is  promising.  However, at least ten
microcosm studies will be needed to produce sufficient
data to identify a suitable index.
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                   Drinking Water
     Results from  this and other research are due  in
the next few years. Information about the degradation
of  low-molecular-weight   chlorinated   hydrocarbons,
polynuclear aromatic hydrocarbons,  alkylbenzenes, and
chlorinated phenols will be available in 1983 and  1984.
Data about the effect of pollution concentration on the
rate of biotransformation will also  be available within
the next two years. By  1985, a model will be proposed
for use in  predicting ground-water  quality, at  a  given
point of water withdrawal, that would result from the
release   of   contaminants   into   the  subsurface
environment.
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           Chapter Four
TOXIC SUBSTANCES AND PESTICIDES

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TOXIC SUBSTANCES AND PESTICIDES
Outline:
Introduction
Legislative Mandate for Toxic Substances
Legislative Mandate for Pesticides
Background
Major Research Issues
     Issue: What monitoring and data handling methods
     need to be developed?
     Issue:  What environmental parameters need to be
     factored into hazard,  exposure  and risk models?
     Issue:  What new tests are needed for chemical
     hazards and risks?
     Issue:  To what  extent do  substances of similar
     chemical  structure  produce  similar  health or
     environmental effects?
     Issue:  What biological responses  are  of concern
     for toxic substances and pesticides?
     Issue:  Does  field information verify pesticide
     exposure models?
     Issue:  How  can pesticide transport and  fate
     models be improved?
     Issue:  What environmental measurements should
     be required for biological pest controls?

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           Toxic Substances and Pesticides
INTRODUCTION

      Man-made chemicals  are  pervasive  in  American
society.   Some of these chemicals  are hazardous to
humans,  plants or  animals.   If used with  careful
controls,,these synthetic substances  can be extremely
beneficial.    If  used  inappropriately,  they can  be
detrimental  to humans and  to  the  stability  of the
environment.

      The  problem  is  illustrated  by pesticides.   By
controlling  pests,  these synthetic chemicals increase
agricultural  production,  lower  food  prices,  and  may
reduce the likelihood of disease in animals and humans.
However, used improperly the  same chemicals can be
toxic to untargeted plants, animals and humans.  These
toxic  effects  may  arise  at  various  points  in the
manufacture, use  and  disposal  of the chemical.  By-
products and  impurities, and  the persistence of the
chemicals in the environment, may increase the health
risk and add to the problems of  defining toxicity and
risk.

      The task  of controlling toxic chemicals in general,
and pesticides  in  particular,  is  twofold:   first, to
prevent  unreasonable  risk  to  human health and the
environment, and  second,  to  ensure that  the  tests
required for the  control  of these substances are as
accurate  and  cost-effective as  possible.   Decisions
about the control of  toxic  chemicals  and  pesticides
must be  based  on accurate information about the costs,
benefits  and risks  of  each  substance.  EPA's  toxic
substances   and   pesticides  research  programs  are
dedicated  to maintaining and improving the  quality of
this information.

      The  purpose of  this  chapter  is  to  explain the
research needs of  EPA's Office  of Pesticides  and Toxic
Substances, to describe the research objectives related
to  those needs,  and  to indicate the  EPA research
activities  planned  to  meet  those  objectives.    In
addition, the chapter will describe the current research
focus and future trends.

      The  toxic  substances  and  pesticides research
program for fiscal year 1983 is allocated $33.7 million.
This  total  is  divided  among two subprograms: toxic
substances   research,  $27.2 million,  and  pesticides
research,  $6.5 million.  The total  resources  for  the
toxic substances and  pesticides research program  are
distributed among the  major  research areas as follows:

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           Toxic Substances and Pesticides
environmental  processes  and  effects,   38%;  health
effects, 35%; monitoring systems and quality assurance,
18%;  stratospheric  modification   and  the   National
Center for Toxicological Research,  5%; engineering and
technology, 2%; and scientific assessment, 2%.

LEGISLATIVE MANDATE FOR TOXIC SUBSTANCES

     The  Toxic  Substances  Control   Act  (TSCA)
establishs EPA's authority to regulate, if necessary, all
commercial chemicals  except  those  uses specifically
exempted in the act.

     Section 4  of  TSCA gives EPA the authority  to
require  manufacturers and/or  processors  to  test their
chemicals  for health or environmental effects.   This
authority is selective, applying  only to those  chemicals
for which EPA makes certain findings as to the need for
testing.   Testing  requirements under Section 4  are
imposed  by  rule,  each rule specifying  not  only  the
chemical  to  be tested, but also  the nature of  the
required tests.  EPA's Office of Toxic Substances is also
using negotiated  testing  agreements to  implement
Section 4.

     Section 5 of TSCA establishes a premanufacture
notification process for  all new  chemicals  or significant
new uses of existing chemicals. The manufacturers of
these chemicals are required to submit information to
EPA for review prior to production.  Unless  EPA finds
that  the  chemical  poses  an  unreasonable  risk  or
demonstrates  the  need  for   additional  testing,  the
chemical  is  placed without restriction  on  the  EPA
inventory of existing chemicals.

     Sections  6  and  7  of   TSCA  provide  control
authority for existing chemicals.  Section 6  is general
regulatory authority  and  Section  7 gives EPA special
powers   to  address  imminent  hazards.    Section  8
provides  EPA  with  information-gathering  authority.
Using  these  three  sections,  EPA  can   limit   the
production, distribution, disposal or use of chemicals to
prevent   unreasonable   risks   to   health    or   the
environment.

LEGISLATIVE MANDATE FOR  PESTICIDES

      EPA's legislative  authority to regulate pesticide
use comes from the Federal Insecticide,  Fungicide and
Rodenticide Act (FIFRA) and Sections  180, 193 and 561
of the Federal Food, Drug and  Cosmetic  Act (FFDCA).
FIFRA gives  the EPA responsibility for determining the
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           Toxic Substances and Pesticides
standards for registration of pesticides for  legal use in
this  country.  Section 3 of  FIFRA provides EPA with
the authority to regulate the use  of pesticides in a
manner which will not result  in unreasonable adverse
effects to  the  public health  and  the  environment.
Sections 180,  193  and 561 of the FFDCA provide EPA
with the authority to set tolerances and exemptions for
pesticides in food  crops  and in  animal feed and food
additives.

      To  obtain   registration   for   a  pesticide,  a
manufacturer must first test specific health and safety
aspects  of   the  substance  using  testing guidelines
suggested by EPA.   Results of  these tests are then
submitted to EPA, which  decides either to  register  the
pesticide for general or restricted use, to request more
information  from  the manufacturer, or  to  deny  or
revoke  registration.   When  a  pesticide  is  registered,
EPA specifications for it include allowable use, means
of  production,  disposal  requirements,  crop  residue
limits,  and  tolerances   in  animal  feeds and food
additives.

      The Registration Standards Program  involves  an
intensive  review of the data  base supporting  already
registered chemicals.  The Special  Review  Program
includes risk/benefit reviews  of registered pesticides
when there are effects  exceeding established criteria
for "reasonableness".  Special reviews may  be launched
if  such  criteria  are   met   or   exceeded   during
development of a  Registration  Standard,  or because
such information is made known to EPA.

BACKGROUND

      In addition to conducting and supporting research
projects,  EPA's research  program  investigates   the
scientific literature  and  follows relevant  projects  of
other federal agencies such as  the National Institute of
Environmental   Health Sciences, the National  Cancer
Institute, the   Food  and  Drug  Administration,   the
National  Center for Toxicological Research, and  the
National Institute for Occupational Safety and Health.

      The  toxic substances  and  pesticides  research
programs are   designed  to  meet  specific  research
objectives  in   support  of  EPA's  enforcement   and
regulatory functions.  Although the  research programs
are  separate, much of  the research being done  and
many  of  the scientific  questions  and   issues  being
addressed are  similar. The programs,  therefore,  are
presented together in this Research Outlook.
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           Toxic Substances and Pesticides
     The objectives for toxic substances research are:

•    Develop methods and provide quality  assurance
for TSCA data and analytical activities.
•    Develop and validate test  methods  to assess
health and environmental hazards of chemicals.
•    Develop and validate methods  to  predict  and
monitor  human   and  environmental  exposure   to
chemicals.
•    Develop  structure-activity  fate   and  effects
relationships in support of  premanufacturing and new
use reviews.

     The objectives for pesticides research include:

•    Define the environmental and health endpoints for
research.
•    Develop methods for improved risk assessments.
•    Develop and validate test  methods to  identify
health and environmental effects.
•    Develop and validate  techniques to assess human
and environmental exposure.
•    Provide quality assurance assistance and support
for  regional/state  laboratories   and  other  FIFRA
activities.

     The key scientific issues now  being studied by
EPA to fulfill both sets of objectives are:

•    What monitoring and data handling methods need
to be developed to meet the requirements of TSCA and
FIFRA?
•    What   environmental  parameters  need  to  be
factored into mathematical  models and what is required
to verify that the models  are accurate predictors of
hazard, exposure  and risk?
•    What  new  tests are  needed to assess chemical
hazards and to evaluate risks of known effects?
•    To what extent do substances of similar chemical
structure   produce   similar    human   health   and
environmental effects?
•    What biological responses are of  concern for toxic
substances and pesticides?
•    Does  field  information verify pesticide exposure
models?  If not,  to what extent  do  the  models need
improvement?
•     How  can pesticide transport and  fate models be
refined to gain greater precision?
•     What   environmental  measurements  should  be
required for biological pest controls.
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           Toxic Substances and Pesticides
MAJOR RESEARCH ISSUES

Issue: What monitoring and data handling methods need
to be developed?

     Many  existing  chemicals  that  fall  under  the
purview of TSCA are difficult to monitor.  Data about
them cannot  be collected or  analyzed with  a high
degree of confidence because of inadequate  methods.
As a result, there is a tendency to  rely on large safety
factors  to ensure the protection of the  public from
poorly defined risks.

     With regard to potentially toxic substances, TSCA
requires  sound and  rigorous monitoring  methods  and
data  collection  and  analysis  techniques.    Such
techniques and methods, being developed to meet  the
mandates of other environmental protection legislation
(e.g., the Clean Air Act),  may suffice  technically for
TSCA.  However, in some cases development schedules
may not  be in  phase with regulatory needs.  Therefore,
EPA's toxic substances research program will focus on
developing and improving key technical methods.

     Method  development  specific  to  TSCA  needs
includes monitoring  methods for collecting field data to
improve   estimates   of  human  exposure,  improved
collection methods  for polar compounds and improved
methods  for  analyzing the  large  quantities of  data
gathered.

     In  addition,  research will  continue  to improve
methods  for both PCS and bulk asbestos.   The PCB
research  seeks to improve ways to differentiate among
the numerous  PCB  isomers and to  develop associated
quality assurance reference  materials.   The asbestos
research  effort continues to  provide quality assurance
audits  and develops measurement techniques to allow
the EPA regulatory offices to assess the effectiveness
of asbestos clean-up operations.

     The risk assessments mandated by TSCA require
exposure  assessments  which  are,  of necessity,  based
primarily on data collected for other  purposes.  With
exposure  becoming  a  more important  factor  in EPA
regulations, research in  this  area  is  focused   on
improved methods  for collecting exposure  data.   In
particular, portable monitors and  biological tests to
document exposure  in individuals will be developed for
specific  chemicals  of  concern.    Methods will   be
developed, using questionnaires and  statistics, to relate
individual  measurements  to  larger  populations.   In
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           Toxic Substances and Pesticides
addition, field sampling techniques will be developed to
monitor exposure pathways, both to provide data and to
validate predictive models.

     A related research area  of growing  importance
involves improved methods and  techniques for handling
the great  quantities of data generated under  TSCA.
Research  is directed at pattern recognition and other
data reduction techniques and  at improving  computer
programs for presenting and relating diverse data sets.

     Because  implementation  of  TSCA  requires  a
greater reliance  on  biological measurements  than did
previous   legislation, quality assurance  research will
focus on developing  laboratory guidelines for  biological
tests,  standardization  of  biological   methods  and
development  of  standard   reference  materials for
biological tests.  Additional quality assurance work will
develop guidelines for validating the  predictive  models
currently  being used in the regulatory process.

Issue:  What environmental parameters need to be
factored into hazard, exposure and risk models?

     Mathematical  models  are used  as  part  of the
regulatory  process   to  assess  the  impact   of  toxic
substances   and  pesticides  on   the  environment.
Effective models share two characteristics.  First, they
realistically   describe  the   physical  and   biological
components of the environment.  Second, they  can be
used to reasonably  predict  exposures and hazards  of
toxic  substances  to individual species  or  designated
populations.

     Mathematical  models of the physical environment
are used to estimate the movement  and concentration
of toxic substances  in the  environment.  Jhe  models
produce  estimates   of  environmental  concentrations
which   are,   in   turn,   used   in   risk  assessment
determinations.  The problem is that  relatively  few  of
the physical models have been validated in  the field;
their precision and  accuracy of prediction need to  be
defined for specific applications.  Field validation may
reveal the extent of uncertainty in the model  segments
that have been exhaustively analyzed and can help to
define confidence intervals. Such analysis  is  key  to
documenting  the reliability and  limitations  of  the
mathematical models.

     To  validate  models,   current  model  users will
define intended  model  use and  determine  the most
important components for  validation.   The  resulting
prioritized list of research  tasks will  be submitted  to
peer review to define the details of research necessary

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            Toxic Substances and Pesticides
to produce models that will yield reliable and accurate
results.

      The approach to be taken is  first to  fine tune a
model's simpler components under controlled laboratory
conditions and then to move to simulation of the  more
complex components, also under  laboratory conditions.
Models will then be  validated in the  field.  One key
assumption to be tested is that components that  work
individually can also  work in tandem.  Field validation
of  the  integrated   components  will   focus  on  the
applications likely  for the  model.  Verification will
include  non-steady-state  conditions  for   time   and
chemical loading  factors.   A  test  model  will  be
developed by EPA,  subjected to scientific peer review,
to review by EPA  program  officials and to validation
and  comment.   If  successfully validated, the method
will  be  formally  announced by EPA  along with  its
intended use and limitations.  Estimates of a model's
precision and accuracy will be part of its description, as
will comparison with other models.

      Major planned results from this research include a
second-generation environmental exposure  assessment
modeling system (EXAMS) in  1983, screening toxicity
prediction models for the estuarine environments, due
in 1984, models to  predict the concentrations of  toxic
substances  in  the air and in terrestrial environments
including ground water,  due  in 1984  and  1986, and
models  to  estimate  human exposures   to  organic
chemicals,  due  in  1985.   Results  expected  from the
pesticides  research  effort  include:    methods  to
quantitatively describe sorption kinetics and exchange
rates in soils and  sediments, and  models to predict
microbial degradation rates,  transformation  processes
and  rate variations for pesticides  in aquatic systems,
due in 1983,  a field  validation and general availability
of a fate  model for  orchards, due   in  1984,  and
improvements  and  field  verification   of  models  to
estimate exposures and risks in 1985 and 1986.

Issue:  What new tests are needed for chemical hazards
and risks?

      The levels of chemical hazard are measured by
tests which use  whole organism  responses to known
concentrations   of    a  chemical  substance.    EPA
establishes methods  based  upon  various  statutes  to
ensure   that   the   tests   are   accurate,  reliable,
economical, and scientifically sound.   Currently,  96
testing methods have been published.  Research is now
underway  to  improve  these  tests,  increase   their
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            Toxic Substances and Pesticides
applicability to other chemical classes, decrease their
costs  and   advance  their  use  in  overall   hazard
assessment.    Also,  more  complex  tests  are  being
developed for upper tiers of a given test scheme.

      Existing  tests  are  designed  to  evaluate  the
responses  of  single  species  of organisms to  toxic
chemicals.  The tests are relatively simple and serve as
first-tier,  screening  methods  for  rapidly  evaluating
whether  chemicals need  more  complicated  testing.
Additional tests are needed to measure and evaluate
multi-species  and   system-level  impacts   of  toxic
substances  and  chemical   pesticides.   Furthermore,
methods  to  evaluate other environmental  processes
must be  added to available test methods, and  inter-
laboratory comparison  (round-robin)  testing  must  be
carried out  to evaluate  test  reproducibility and  the
expected  range of error.   Subsequent microcosm  and
field testing  of the  methodologies  will validate these
procedures.

      Ongoing  EPA research and that  of other federal
agencies  including NCI, NCTR, and FDA, will  enable
EPA to produce  a completed  spectrum of  lower-tier
testing schemes.    Development  of  upper-tier test
methods will continue.

      Among  the  major  planned products of the toxic
substances and pesticides research effort are:

o    Inter-laboratory comparison of  tests using benthic
marine organisms  for ecological hazard  assessments,
 1983.
o    Short-term   assays  to   define  ecological  risk
associated with sediment-bound toxic chemicals, 1983.
o    Use of fish as surrogates  for mammals  in toxicity
studies, 1984.
o    Established criteria for judging the usefulness and
validity of  test  results  in freshwater,  system-level
assessments,  1984.
o    Guidelines on laboratory-to-field extrapolation of
toxic stress on estuarine macro-benthic communities,
 1984.
o    Data  base development  and  field  validation of
tests for predicting effects  of  toxic chemicals in
marine systems, 1985.
o    Field    validation     of    laboratory-derived,
microcosm, bioassay and effects test methods, 1985.
 o    Test methods for  use in defining possible hazards
 of  chemicals  for:    cardiovascular  disease  (1984),
^immune system impairment (1985), mutagenesis (1985),
 reproduction   (1985),   neurobehavior   (1986),  cancer
 (1986), and liver/kidney  impairment and disease (1986).
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            Toxic Substances and Pesticides
o     Short-term    testing    methods   for   specific
neurophysical,   neurochemical   and   neurobehavioral
changes to screen for the effects of toxicants, 1986.
o     Assessment  methodology  for  human  heritable
effects of chemical exposure, 1985.
o     Development  and validation of short-term, cost-
effective  methodology  for identifying  the teratogenic
potential of chemicals in order  to support or eliminate
the need for extensive animal tests, 1985.
o     Development of methodology for the prediction of
potential reproductive toxicity  which may be used in
determining  the   need  for  two-generation  animal
studies, 1986.

For the pesticides research  program, planned  products
include:

o     Techniques for  culturing and maintaining aquatic
"indicator" organisms (e.g., fish  and invertebrates) used
in toxicity  testing, 1983.
o     Acute and chronic testing studies to determine
critical life-stages  of  exposure to  toxicants  and  to
determine  pesticide toxicity  (dose) and effects on  key
species, continuing.
o     Studies  to  compare  laboratory  toxicity  test
results with findings from field studies, continuing.

Issue:  To what extent do substances of similar chemical
structure produce similar human health and environ-
mental effects?

      The   results   of  careful  studies  on  molecular
structure   and  specific activities,  or  reactivities,
indicate that compounds of  similar chemical structure
may  have  similar  biological  properties  and  effects.
This   phenomenon    is   called    structure/activity
relationship or SAR.

      Structure-activity  relationship  analysis is  a  key
part of EPA's evaluation of  new chemicals under  the
premanufacture notification (PMN)  program.   Most
PMNs are accompanied by little test data on health or
environmental effects.   As a result, EPA employs SAR
analysis to set priorities among  PMNs  in  terms  of
potential  hazard and  to build  the  case  for requiring
testing under Section 5(e) of TSCA.   Similarly,  EPA
may use SAR analysis to support testing  requirements
or to guide in the selection of the most appropriate
tests  for existing chemicals under Section 4 of TSCA.

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           Toxic Substances and Pesticides
     The SAR approach is an attractive and potentially
useful  one  which  may be used  to  produce rapid,
inexpensive, scientifically acceptable data to evaluate
the biological effects of chemicals and thus to improve
risk assessment.  With verified SAR methodology, data
collected and  validated  on  one chemical could  be
applied to another chemical of similar structure.  This
could eliminate or  reduce the  time and  expense of
testing   and  evaluating   the  newer   chemical  for
environmental and health dangers. Moreover, SAR data
that showed the possibility of chemical properties or
effects   of  concern  could  be  used to optimize  the
allocation  of  test  and evaluation  resources  among
specific  compounds  to target  the most  potentially
dangerous substances first.

     Other  organizations  are  also  involved  in  SAR
research. The Food and Drug Administration continues
to investigate  SAR, with  emphasis on human health
effects.  EPA is interested in  both  health effects and
environmental fate and effects. A number of industrial
and  private   laboratories,  as well   as  academic
institutions, are also developing SAR methodologies.

     EPA's  research program in verifying  SAR  began
with a review of research  done by the FDA, chemical
companies  and private laboratories.  Data  on a  wide
variety  of  compounds are  being collected  from these
sources   and  from  EPA's research  to  identify useful
correlations and define the applicability and  limitations
of recognized correlations.

     The research has two objectives:  to develop a
data base of existing information and correlations, and
to determine the cause-effect relationships between a
chemical's  molecular structure and  its  behavior in the
environment.   Currently  there are some  recognized
scientific methods  that can be  applied to  determine a
compound's environmental fate as it  relates to chemical
structure.   Methods  to  determine the  relationships
between environmental effects  and structure require
further development.

     The  chemical   compounds  emphasized in  the
research effort will be selected from a prioritized list
of those chemicals which are most hazardous and most
frequently  proposed  for manufacture.   By 1985 the
research effort will produce preliminary  SAR models
for evaluation of environmental fate and toxicity of a
number   of   classes  of   chemicals   in  various
environmental   media.     By   1986  EPA  will  be
investigating  a   system   using molecular  structure
descriptions and  combinations to predict  genetic and

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            Toxic Substances and Pesticides
carcinogenic activity in humans.  Research will begin to
define  a  set   of   performance  characteristics  that
compare predictions with defined sets of  field  data to
estimate the models' precision and accuracy.

      EPA's research seeks  to  extend the applicability
of SAR use. The results of this work will  be applied to
assuring that the uses of pesticides and other chemicals
are properly controlled.

      Major research products planned  as part of the
SAR effort include:

•     Prediction capability  of toxicity of  12 classes of
chemicals to selected fish species, 1983.
•     Development of a model for predicting toxicity of
organic compounds to selected marine biota, 1983.
•     Provision of an SAR analysis of the S. cerevisiae
mitotic recombination data  set, 1983.
•     Definition  of  thermodynamic   properties   of
chemicals   used  to   estimate   reactivity   in   the
atmosphere, 1984.
•     Production of  a  preliminary model for predicting
toxicity to terrestrial plants and animals, 1985.
•     Field   validation  of  preliminary   SAR   models
developed with laboratory-derived data,  1985.
•     Development  of  an SAR method using molecular
electrostatic  interaction potentials as  a screen  for
predicting toxicity,  1985.
•     Assessment  of  genetic  activity  vs.  chemical
structure based upon GENE-TOX  and  similar  data
sources, 1985.

Issue: What biological responses are of concern  for toxic
substances and pesticides?

      A biological response is a discernable reaction in
an  organism to exposure to toxicants.   This  response
may be used as an indicator of effects or  as a targeted
endpoint.  For human health,  endpoints of concern as
indicators   of  reactions   to   toxic substances  are
reasonably  well defined.   These  endpoints   include
cardiovascular  disease, immune system  impairment,
reproductive dysfunctions, neurobehavioral defects and
cancer.  One specific new  indicator for biological pest
controls  that   use   baculoviruses   is   mammalian
immunological  effects.   Data  on  this  endpoint  are
currently being developed.

      The biological responses  for  ecosystems, on the
other  hand, are not yet well defined.    This  problem
arises  because environmental  toxicology focuses  on
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           Toxic Substances and Pesticides
"populations,"  and  biological  complexity  increases
significantly from  an  analysis of  populations to field
studies  of  ecosystems.   Thus,  while  some specific
indicators  in single-species  environments have been
identified  by validated tests,  there is  no  accepted
means to  extrapolate  the  effects  indicated by these
responses to the multi-species, complex communities of
an  ecosystem.     Moreover, the   ability to  predict
ecosystem  effects without collecting  extensive  and
expensive data does not yet exist.   Research is  needed
not only to identify what the environmental  responses
should be, but also to  determine the biological kinetics
associated with species and ecosystem resiliency  and
recovery.

      EPA's  research   effort is  beginning to  define
quantitative environmental  indicators.    For  toxic
materials in general, they will be identified in terms of
their  commercial  significance —  a possible indicator
may  be  retarded  growth  or  degraded quality  of
commercial crops.  Existing data  will be  analyzed to
identify  research  to   quantify responses or,   at  the
minimum,   to  qualitatively  estimate  them.    Field
validations  of  the estimates  will be  compared  to
existing data.

      By  1988  a  catalog  of  terrestrial   and  aquatic
environmental  responses will be   available.    If  the
indicators  in the catalog suggest  adverse  effects from
toxic chemicals or pesticides, analysis of  the data  will
indicate  whether the biological response quantitatively
or  qualitatively  measures  the   degree   of  adverse
environmental impact.

Issue:  Does field information verify pesticides exposure
models?

      Sophisticated   laboratory   models   have   been
developed to determine the  fate  of pesticides in the
environment.  The output from  these models is being
used to predict, in part, the exposures to the ecosystem
components and to humans and to assess the subsequent
risks  from those  exposures.   Much  of   the   output,
however,   is   not   validated   with   specific   field
measurement.   EPA's pesticide research  program  will
perform the field validation.

      The proposed field studies seek to replicate actual
pesticide use conditions.  Models  using pesticide data
for crops  grown in a  variety of circumstances  will be
validated with field studies.  One  example is an EPA-
developed pesticide orchard ecosystem model  (POEM)
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           Toxic Substances and Pesticides
that predicts the distribution of  pesticides in or  on
trees, grass, broadleaves, litter and soil.  POEM will be
validated in an orchard in the Northwest.

     A cooperative study  between EPA and the U.S.
Geological Survey in Georgia will  gather field data on
the  migration of  pesticides  through soil  to ground
water.  The results  will be used in evaluating several
predictive   leaching  models.    Studies  will  also  be
designed for pesticides used against specific pests.  A
field study  using actual mosquito control pesticides of
an organophosphate or carbamate base applied to  ponds
will measure population changes  to  the  pond's  non-
targeted     organisms,     as     well     as    brain
acetylcholinesterase  and  pesticide  residues  in  fish,
aquatic  invertebrates  and  food.  Development  of  a
mosquito pesticide  model  will be coordinated with a
regional  mosquito  control  program  in  a   Midwest
metropolitan area.

     The approach  taken  in  the  research  is to  use
existing data and  "targets-of-opportunity"   for  the
validation.   One such  target of  opportunity  involves
validation of an  estuarine  exposure  model  using  field
data collected from the kepone contamination of the
James River and estuary.

     Information  from  this research will help in the
evaluation    of    data    submitted    by    pesticide
manufacturers for EPA registration decisions as well as
in the confirmation of limits  specified as part of the
labeling requirements.   In the long run, field-validated
models are  expected to improve future  EPA pesticide
decisions by making them more  timely, cost-effective,
accurate and credible.

Issue:  How can pesticide transport and fate models be
improved?

      Mathematical  models  are  used  to   assist  in
prediction of pesticide transport, fate  and  exposure.
Currently, the models  for  exposure and  fate  are being
worked on  to improve the precision  and reliability of
their predictions  of environmental  concentrations of
pesticides  and toxic substances.  Subsequently,  these
models  will be  validated  in  the  field.   At  present,
improvements are  being  made   along  several  lines,
including integration   of  single-medium models  into
multi-media models, development  of models to predict
concentrations when source input varies with time, and
validation of existing models in microcosms and field
ecosystems.
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           Toxic Substances and Pesticides
     Improvement  of  the  mathematical  models is an
exacting task, due to their  complexity.  The models are
made up of components that represent conditions in the
field.  The hazard  component identifies  and  measures
potential adverse effects, and  is derived from biological
analyses and  stated in biological terms.  The exposure
component   is   described  in   terms   of   pesticide
concentrations in various  media.   These components
must be integrated in  a way  that allows  the  model to
serve as a useful tool in assessment of environmental
risks.

     EPA's    research   seeks   to   improve   the
mathematical  basis  for  determining  environmental
risks.    Initial  work  will  refine  the  environmental
exposure assessment models to fit more closely into the
risk  framework.   The  output  will be  an  improved
mathematical model for more accurate estimates of a
pesticide's impacts.

     Much of the effort will  involve a careful review
and screening  of data that  is  available through the
pesticide registration  process.   Researchers  will  also
review  data  from specific  projects, such  as one which
will take a census of terrestrial non-target organisms at
a pesticide spray site.  Other  data, such as data on
reproductive  dysfunctions in humans and  other species,
will also be studied.

Issue: What environmental measurements  should be
required for biological pest controls?

     Within  the past few  years  an increasing interest
has developed  in the use of  biological control agents
(BCAs)  to control pests.  Over the last five years, the
number of EPA-registered  BCAs has  increased  three-
fold.    The  BCAs  consist  of  two  distinct categories,
biochemical  pest control  agents  and microbial  pest
control agents.  The  former are  biologically  derived
chemicals (e.g., hormones  and  pheromones)  and the
latter  are living microscopic organisms.  The living
organisms currently registered for use include bacteria,
fungi, protozoa and viruses.  These microorganisms are
known  to attack targeted  pests but their transport,
persistence   and fate  in  the environment and  their
effects   on   non-target  species   are   not   clearly
understood.

      The USDA and public and private institutions are
currently conducting research on BCAs.  Their research
emphasis is  on  development  of new agents, efficacy
testing and  control of  target pests.    Environmental
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            Toxic Substances and Pesticides
research is needed to evaluate problems associated with
non-target  organisms.    In  response  to  the  EPA's
regulatory needs, the pesticide  research  program  will
investigate  and  evaluate  hazard  data  to  determine
effects from  microbial  BCAs and from  some of  the
biochemicals  (excluding pheromones and  hormones) in
estuarine, freshwater and terrestrial ecosystems.

      The hazard research will include  a broad  range of
investigations.     To   determine  the    infectivity,
pathogenicity or  toxicity of biological control agents in
the different  media, exposed animals will  be observed
for behavioral effects.  Necropsies will be  performed
and  tissue samples  will  be subjected to  histological,
biochemical and genetic analyses to detect the  fate and
possible effects of the agent in non-target organisms.
For the freshwater analysis, the control agent  Bacillus
thuringiensis  will   be  used  to   measure  exposure
concentrations from  suspension in the  water and from
diet  and injection.  The range of hosts attacked by the
microorganism and its  stability and persistence will be
determined.  The work is intended to determine if test
data accurately predict the field  data.

      Major planned research products include:

•     Determination  in the terrestrial environment of
the scope of the effects already  known to  be caused by
BCAs, 1983.
•     Development   and  testing  of  selected   tier  1
protocols   for   estimating   hazards  to   non-target
terrestrial species.   Microbial  agents will be studied
with  emphasis on  dosing  regimes, appropriate  non-
target endpoints, and survival and  persistence of BCAs
in the environment, 1984.
•     In situ testing of Bacillus thuringiensis with non-
target freshwater  organisms  under  field  conditions,
1985.
•     Laboratory  exposure  studies using aquatic animals
(estuarine) and insect viruses, 1984.
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Chapter Five
    AIR

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AIR
Outline:
Introduction
Legislative Mandate
Background
Major Research Issues
     Issue:  How do people sensitive to air pollutants
     respond to those pollutants?
     Issue: What monitoring and measurement methods
     are needed  to detect and analyze air pollutants??
     Issue:    What  models   best  describe pollutant
     transport and transformation?
     Issue: How can air quality models reflect complex
     terrain conditions?
     Issue:  Can sources  of  pollution  be identified by
     the  unique  properties  ("fingerprints") of  their
     pollutants?
     Issue:  What are the health effects from exposure
     to  combinations of pollutants?
     Issue:  What is the cost of damage to crops from
     air pollution?
     Issue:  What  are  the  most  effective emissions
     reduction  technologies  for  volatile  organic
     compounds,  nitrogen  oxides  and    other   air
     pollutants?
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                         Air
INTRODUCTION

     There  are  four  major  air  pollution  research
programs at EPA.

     The gases and particles program is concerned with
the health  and environmental impact of sulfur  oxides,
particles and lead.

     The   oxidants  program  studies nitrogen  oxides,
ozone and  ozone precursors, which are either directly
emitted or formed as a result of atmospheric chemical
reactions.   Volatile  organic compounds (VOC)  are an
important subset of these precursor chemicals.

     The   hazardous air pollutants   program   studies
pollutants  listed by  EPA as hazardous and investigates
others  which may require regulation.  After screening
approximately  600 high-volume  production chemicals,
EPA's Office of Air  Quality Planning and Standards has
identified  37 compounds as  being of high priority for
more intense investigation.   Research during the next
two years will assess the health risks of these chemicals
and  help   to  determine   the   need  for   further
investigation.

     The  mobile sources program  produces scientific
information  needed  for assessing  the  impacts  of
vehicular  emissions.  Major pollutants  of  interest are
carbon monoxide (CO), diesel particles and unregulated
organic emissions.

     The  air pollution research program for fiscal year
1983 is allocated a total of $59.4 million.  This  total is
divided among  four  subprograms: gases and particles,
$31.9 million;  oxidants, $13.1 million;  hazardous  air
pollutants,  $8.6  million;  and  mobile  sources,  $5.8
million.

     The  total resources for the air pollution research
program are distributed among the research disciplines
as follows:  environmental processes  and effects, 31%;
health  effects,  27%; monitoring  systems  and  quality
assurance,  21%; engineering  and  technology, 15%;  and
scientific assessment, 6%.

LEGISLATIVE MANDATE

     The  Clean Air Act (CAA), as amended in 1977,
gives EPA  the authority to  set minimum standards for
air  quality.    State   and  local  governments  are
responsible for  preventing  and  controlling  pollution
sufficiently to  attain those  standards.  EPA's research
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                         Air
role under CAA is to conduct research and development
programs to acquire the information needed to support
both  defensible   standards   and  the  air   pollution
regulations necessary to attain them.

BACKGROUND

     To meet CAA requirements, EPA's air pollution
research programs address two major tasks — gathering
data on the currently regulated air pollutants in order
to revise standards on a periodic basis, and compiling
data on unregulated pollutants to determine whether
potential health and environmental risks may warrant
future standards.  In the first  case, the research refines
and  extends existing  findings.   In  the second,  the
research establishes and tests  hypotheses. Data derived
from both efforts will support  the National Ambient Air
Quality   Standards  (NAAQS),    the   New   Source
Performance Standards  (NSPS), the National Emissions
Standards for Hazardous Air Pollutants (NESHAPS), the
Prevention   of   Significant   Deterioration    (PSD)
increments and mobile source  standards.

     The results of research  on  certain air pollutants
are compiled in "criteria documents" which are required
by section  108  of  the CAA and which  provide  the
scientific criteria  upon which  many regulatory decisions
are based.  Currently,  criteria documents have  been
published for the pollutants regulated by NAAQS under
Section 109 of the CAA.  These pollutants are ozone,
nitrogen dioxide, sulfur oxides, carbon monoxide, total
suspended particulate matter, lead and hydrocarbons —
the "criteria pollutants."

     Further   research  on   criteria   pollutants  is
performed to refine the knowledge base underlying the
standards.  For example, questions may include: Should
the standards be  higher or  lower?   Should different
descriptive  units  for   pollutants  be  devised (e.g.,
particles 10 microns and under)?

     Research  into  hazardous  air  pollutants (those
regulated under section  112  of  the CAA)  asks  such
fundamental questions  as:   What pollutants  are of
concern?   How   dangerous   are  they?     In what
concentrations?   What  are actual human exposures to
these  pollutants?   Results  from  this research  are
published in health assessment documents.

     Major  themes cut  across the air pollution research
programs and the issues associated with them.   For
example, ambient  air concentrations of a pollutant at a
fixed point  may not realistically represent  the actual
exposure that will determine adverse  health  effects.

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                         Air
For  some  pollutants,  it  is  now  possible to  measure
directly   an  individual's  total  exposure,  including
exposure at work or at home.  Such measurements will
significantly improve  EPA's knowledge of actual 24-
hour  exposure,  the  spatial  representativeness  and
temporal  variability of ambient concentrations and,
consequently, estimates of actual health risks.

      Research is needed, however, to develop methods
for more realistically determining  exposure to other
pollutants.  For example, little information is available
about hazardous air pollutants, their concentrations and
distribution.  Research  is now attempting  to  resolve
both the new and  the long-standing arguments about
estimating cancer risks, evaluating mutagenic hazards,
determining  effects  to  reproductive  systems  and
estimating  the potency  of toxic  pollutants.   This
difficult   work  is   further   confounded   by   the
uncertainties associated with extrapolating  from data
on animals to prediction of effects in humans.

      Currently,  hazard  assessment   documents  are
being  prepared  on  37  potentially  hazardous  air
pollutants.   In  addition, determining the  potential
interactions of  these  pollutants to form products of
greater or  lesser toxicity  remains a  major research
challenge.   However,  one of the problems  with field
measurements  is that,  in many  cases,  measurement
technology is inadequate to  detect and measure such
pollutants  in  ambient air.   Technologies for  making
measurements  in the  ambient  environment are now
being modified or developed,  especially  for technologies
for  measuring  organic  compounds found   in  urban
atmospheres.

      Air pollution may pose  greater risks to the health
of certain more susceptible groups of people than to the
remainder  of  the  population.    Research  is  looking
increasingly at populations  at  presumed  greater risk.
Similarly,  health  studies  using  test  animals  now
concentrate on chronic, long-term, low-dose  exposures.
The  lower  doses often  portray more  accurately the
pollutant levels seen in  the  environment.  Such long-
term, low-dose health  research  may help to determine
if  linear  or  non-linear  dose-response  curves more
accurately estimate the  probability of human health
impairment   from  exposure  to  low  doses   of  air
pollutants.

      Other  air pollution  research will  improve  the
scientific basis of models, validate models in the field
and improve laboratory methods to refine the models.
The   models   range  from   atmospheric   transport,
transformation, diffusion and   deposition models,  to


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biological tests that  can be  used to  determine  t
presence  of   certain  compounds   and  to   sere
compounds for potential toxicity.  Once these mod«
are developed, they will be tested for accuracy.

     The major  research issues  responding  to  tl
problems mentioned above are:

•    How do  people sensitive to air  pollutants  respoi
to those pollutants?
•    What  monitoring  techniques and  measureme
methods are needed to detect and analyze air pollutan
and/or predict actual population exposure?
•    What  air  quality  models  best  describe  tt
regional,  mesoscale  and  urban scale  transport  ai
transformation of pollutants?
•    How can air quality models reflect the transpo
and diffusion of pollutants  in complex terrains?
•    Can sources  of pollution be  identified  by  tf
unique properties ("fingerprints") of their pollutants?
•    What are the health effects  from exposure
combinations of pollutants?
•    What is the  cost  of damage to crops from a
pollution?
•    What are  the most effective emissions reductk
technologies  for volatile organic compounds,  nitrogc
oxides and other air pollutants?

MAJOR RESEARCH ISSUES

Issue:  How do people sensitive to air pollutants
respond to those pollutants?

     Health  responses of members  of the populatic
most sensitive  to  air pollution exposures  need  to fc
determined to assure these people  an adequate  level c
protection.   Among the groups identified as sensitiv
are  the  elderly, asthmatics, those  with   chroni
obstructive  lung  disease  (e.g., emphysema),  persor
with coronary vascular disease and  children.

     EPA's air pollution research programs are  buildin
upon a data  base derived  from air pollutant exposure:
The existing  data  base  for effects  in  healthy peopl
demonstrates that some  persons  exposed  to  varioi
pollutants  exhibited   exaggerated   responses  such  a
increased   sensitivity  to   bronchoconstrictors   an
increased airway resistance.  Such  responses have bee
seen either from constant or  intermittent exposure t
low  levels of  pollutants  over a period of time  or fror
low  levels  of  exposure with  repeated  higher  peak;
Studies previously  done  by other investigators  need t
be replicated, and further characterization is needed o
effects observed in response to various exposures ove
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long  time  periods.   Other studies are  needed  of
immediate responses to short-term exposures.

      The EPA's research will include epidemiological,
clinical and animal studies.  The clinical studies will use
volunteer human subjects exposed to pollutants in EPA's
clinical exposure facility.   These persons are exposed,
both  at  rest  and  while exercising, to  pollutants  at
concentrations  bracketing   ambient   levels.     All
exposures are acute (short-term) exposures.   Subjects
will  be tested before,  during,  and  after exposure to
determine pulmonary function performance, effects on
biochemical  parameters,  and  effects  on  peripheral
lymphocytes as an index  of immune function.

      Normal, healthy  individuals  of both  sexes  and
several races are  being tested.   In  addition,  other
groups of  people  suspected to  be susceptible will  be
exposed  to low levels of ozone,  NO,,  SO2  and fine
particle aerosols alone and in combination and tested to
characterize  thresholds   of   effects   if   possible.
Asthmatics will   be  studied,  using ozone,  nitrogen
dioxide and sulfur dioxide both alone and in combination
with  aerosols  in  tests  designed  to  model ambient
conditions.   Persons  with  chronic obstructive  lung
diseases will  be  studied  using the same  pollutants.
Persons    with    pre-existing   conditions,    enzyme
deficiencies   such  as   alpha-1-antitrypsin   globulin
deficiency, for example, which may predispose them to
increased pulmonary responses,  will be also studied. In
addition,  non-invasive methods  using a gamma camera
to measure ventricular  wall motion can  be  used to
monitor the heart.  Such methods will be used to study
the effects of carbon monoxide  on persons with existing
coronary  artery disease prior to the onset  of clinical
symptoms such as angina.

      Animal tests  are investigating both the increased
susceptibility to respiratory infections and development
of arteriosclerosis  to determine if they are influenced
or caused by exposures to air pollutants.  Studies will be
performed on both  healthy rodents and those  treated to
simulate conditions such as asthma or emphysema using
long-term (chronic) exposure regimens.

      Additional  studies will examine  differences in
sensitivity  among  various  species of small  mammals.
These results will be useful for  extrapolating effects in
animals  to  those predicted  for  humans,  especially
effects  from  long-term  exposures or  exposures  to
higher  concentrations   of  pollutants.    This  is  true
because by pointing out  common responses  or different
responses  in different species and correlating them to
known differences between species it should be possible

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to better predict human responses based on knowledge
of human physiology.

     Data  on  chronic  pulmonary,  pathological  and
immunological effects of ammonium  sulfate and sulfur
dioxide on normal  animals and animals with impaired
respiratory functions will be available in 1987.  Results
will  contribute  to  revision  of the particulate matter
standard.    In 1987,  data  will  also be  provided on
respiratory,    morphological,    immunological   and
metabolic effects of  NO2 exposure in animals  treated
to simulate pollution-sensitive human groups.

     Further  studies  will  evaluate   lead  exposure
absorption/retention    relationships    in   sensitive
populations.   Previous  findings indicated effects at
lower  exposure  levels than expected.  Additional  data
on the sensitivity of neurological, behavioral  and other
health factors in children exposed to low levels of  lead
will be available in  1986.

     Research will also provide data on physiological,
biochemical and immunological  responses  to exposure
to single  and combined gases and particles  in normal
populations and those in sensitive population subgroups.
Additional studies will analyze major urban particulate
pollutants  (sulfuric  acid and   ammonium  compound
aerosols) alone and in combination with ozone, nitrogen
dioxide and  sulfur dioxide.  Results of this work will be
available in 1987.

Issue:  What monitoring and measurement methods are
needed to detect and analyze air pollutants?

      Effective modeling, control, and regulation of air
pollution  depend on  rapid  and  precise  methods  to
measure  air  pollutant  concentrations  in  both   the
ambient  atmosphere   and  from   specific  pollutant
sources. This means that an underlying  theme of EPA's
monitoring  research  is  the  development  of  new
measurement  methods and of quality assurance programs
to ensure that methods currently in use are reliable.

      In addition to working to improve site monitors,
EPA  research will develop non-invasive  monitors  to
gather physiologic data  while collecting exposure data.
These  monitors  will  be miniaturized for  use  in  field
studies to gather accurate data under  actual ambient
conditions.

      For    hazardous    air   pollutants,   monitoring
technologies and measurement  methods are  needed to
determine precisely the composition of the air and to
help to identify those  air  pollution components  that

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represent a significant health risk.   Current  collection
instruments   were  not  designed  to  measure  these
compounds.  One major research goal is to develop and
deploy monitoring devices to  determine if  there are
pollutants in  the air which are, or  may be, hazardous.
Protocols for the  new technology  must  be developed,
field-tested  and verified.   Most existing methods  to
monitor  hazardous  air   pollutants  employ polymer
collection  capsules   in   conjunction   with  a  gas
chromatograph  (GC)  and  mass  spectrometer  (MS).
However, some compounds  known  to be biologically
active "cannot  be  collected  with the current polymer
capsules;  new polymers  are  being  investigated  to
collect the potentially toxic compounds.

      EPA recently sponsored the development of a new
technology to supplement the  GC/MS  measurement
process:  the  tunable atomic-line molecular spectrum
(TALMS) device.  TALMS uses magnetic field excitation
to  identify  compounds.    EPA research  is currently
sponsoring development of a library of spectra for use
in identifying compounds.

      EPA's  research  approach to  the  hazardous air
pollutant problem  is to take  measurements with state-
of-the-art equipment while simultaneously developing,
testing, refining and verifying new  technology. EPA is
establishing  a regional  monitoring center that can
perform  the sophisticated analyses  necessary to detect
hazardous air pollutants.  The center will also act as
the  contact  point  for  new  stationary  or  mobile
measurement technology.

      As   the   new    monitoring   and   measuring
technologies  are  developed, they  will  be  used for
identifying,   screening  and  characterizing  hazardous
atmospheric  pollutants.  Emphasis of this research will
be on   quantifying the  atmospheric  transport  and
transformation processes (i.e., chemical  reactions and
dispersion)  that  govern  the  ambient   concentration
distributions   of  primary  and  secondary  (derivative)
hazardous air pollutants, and on determining the effects
environmental processes  have on  the   frequency  of
occurrence, ambient concentration ranges and patterns
of variability observed for hazardous air pollutants.

      Similar  to  the proposed change in the particle
standard, there  may  be  a change  in  the  way  of
calculating   personal   exposures  to  hazardous  air
pollutants.   Currently, exposures are estimated  using
data  on  emissions and concentrations of  the pollutants
in the ambient atmosphere.  However, total exposures
based on actual 24-hour personal exposures  may differ
from those estimated from the ambient concentrations.
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     For   measuring   personal   exposures,   EPA  is
developing new  methods to work in concert with the
new or modified technology  for  measuring  ambient
exposures. The  results, which may be definitive within
the  next   half  decade, will  help  to determine the
appropriateness  of the current regulations for the seven
listed  and four  regulated  hazardous  air pollutants  as
well as the  potential need  for  regulations for other
pollutants.   The research program for hazardous air
pollutants  is  expected  to gain  increasing  emphasis
during the next few years.

     Mobile  sources research seeks to determine the
extent of  human exposures to mobile-source pollutants
such  as CO, NC>2, diesel particles  and  unregulated
organic emissions.   Continuous,  real-time  personal
monitors  are presently being  used  to  measure CO
concentrations.    NOj  badges  sensitive  enough  to
provide data  on exposures at ambient concentrations
have  been developed.   Portable  devices  capable  of
collecting  airborne  particles  and gases for laboratory
study  have also been  developed.  Measurement and
analytical   procedures   for  unregulated   pollutants,
however, need to be refined or developed.

      Refinement of analytical procedures that apply to
a variety of unregulated pollutants is needed in order to
be  able to use the procedures  for analyzing priority
pollutants. Furthermore, development of the analytical
procedures is needed for measuring pollutants that are
not completely characterized  and that pose a  potential
carcinogenic  threat, e.g.,  organics adsorbed on diesel
particles.   Research work is attempting  to  develop
bioassay tests as an analytical procedure applicable to
emissions from  various fuels and fuel additives.   In
addition to the evaluation of pollutants from current
vehicles,  these  procedures will  be needed to  identify
and assess the  health  effects of new pollutants  from
changing fuels and engine technologies.

      Research  for  studying  human  exposures  to CO
from mobile sources will be emphasized.  Even though
nationwide  CO  emissions have been decreasing, the
relationship between vehicle emission rates and actual
CO exposures needs to be more precisely  determined.
By  developing   a  reliable  predictive   method  for
determining population  exposure profiles in  urban areas,
CO exposures can be determined and exposures to other
mobile-source-generated   pollutants  can   be   inferred
using the CO data  as a surrogate.  The most critical
portion of the determination  of these exposure profiles
is  the development of  sampling  methods  that can
adequately  characterize   CO  levels  in  important
microenvironments.
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                         Air
      CO exposure research will also determine whether
existing, fixed, in-place monitoring sites for measuring
air pollutant  ambient  concentrations  are sufficiently
representative of actual CO exposure  concentrations.
Studies,  for   example,  have   shown  that  curbside
measurements vary significantly from  sites at slightly
different  distances  from,  and  heights  above,  the
roadways.

      The  exposure  data  can be  used  to: (1) assess
better the  health risk  of  CO  to  the  population, (2)
provide  a  basis  for  improving  the  siting of existing
monitoring stations, and (3) validate existing  exposure
models.  This  validation is particularly important. Field
data are needed  to further validate  estimates used in
establishing the National Ambient Air Quality  Standard
for   CO.      Those   estimates    were   statistical
approximations   of  the percent  of  the  population
exposed  to various CO  concentrations; actual  exposure
data  are  essential   for determining  whether  future
emission standards or  air  quality  standards should be
relaxed  or  made more stringent.   Exposure models
field-validated for CO will be important for  other
mobile   source   pollutants   as  well.    As the  first
statistically   representative  data   base  on   human
exposures for a  criteria air pollutant, it will  serve as
the research benchmark for data bases to be developed
for the other mobile-source air pollutants.

      The research approach is to  develop a data base
collected by volunteers who will carry portable carbon
monoxide monitors developed by EPA.  The  monitors
are  miniature (about  the  size  of  a small  camera),
accurate, reliable and  durable.   By  choosing  a cross-
section of  the population,  correlations made  between
exposures and urban-scale  activities can  be  used as
scientific estimates of  realistic exposures to pollutants
from mobile sources.

      Data  from the personal monitors will also be used
to validate  and improve existing computerized  human
exposure models  such   as  the  SHAPE (Simulation of
Human Air Pollution Exposure) model.  Such models are
used to  assess the impacts, in terms of exposure, of
changes in emissions and activities.

      To assess the proper level of control of  particles
from  diesels, information  is  needed  on projected
exposures of  populations  to diesel  particles  and  the
long-term health effects from the exposures.  Health
effects   studies   are   being  completed  and  risk
assessments for  diesel  emissions will be completed in
1983.   Risk  assessments   need  to  be developed  for
unregulated  mobile  source  emissions  that  pose  a
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potential   carcinogenic   threat,   e.g.,  nitrosamines,
formaldehyde and dioxins.

     In  general,   most   toxic   air  pollutants   pose
problems near to their sources but not  over an entire
urban  area.   This  is  also  true  of  some  criteria
pollutants.   In the mobile sources research program,
there is a continuing effort to  determine emission rates
for many of these  pollutants.   Such source studies of
emissions may provide important input into determining
the  cost   effectiveness   of   alternative   emissions
reduction strategies.

     For gasoline-fueled  cars and  light-duty trucks,
emissions controls  are relatively  mature.  For  these
sources,  research  focuses on  developing more precise
emissions inventories  for  volatile  organic  compounds
under different driving conditions.  Such information is
important  for maintaining air quality  standards.   For
other vehicles — especially heavy-duty trucks and buses
— research will aim at determining the impacts on  air
quality   and human  health of  alternative  emissions
reduction scenarios.

      The  oxidants  program  will  develop measuring
methods  to help  determine   the  reactivity  of   air
pollutants  and the photochemical formation of  smog.
Emphasis of the program  will be on refining  existing
monitoring technology and quality assurance.

Issue:  What models best describe pollutant transport
and transformation?

      When pollutants  are  emitted into the atmosphere,
they  often  undergo  chemical   and  photochemical
reactions that change  the  initial pollutants into a range
of  different compounds.   To  predict this  phenomenon
requires  that  chemical   process  equations  (e.g.,  for
reaction rates)  and physical  process algorithms  (e.g.,
for dispersion) be integrated into one model.  Regional
transport   and   transformation   models   are  being
developed for sulfur dioxide, sulfates,  particles, ozone,
nitrogen   dioxide   and   nitrates   including  natural
emissions  of hydrocarbons.   The models  will provide
information on how  upwind  pollutant sources affect
downwind urban areas.  This information will be key to
developing effective pollution  control plans.

      The   chemistry  portions of  the regional-scale
models are now sufficient  to describe some atmospheric
reactions.   Field studies will be conducted to  verify
calculations that describe  the formation  of  sulfates
from SO.,, the formation of particles, and the reactions
that produce ozone.
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      Not as well developed, however, are the physical
algorithms.  The traditional approach to such modeling
was based on Lagrangian models which are point-source
and area-source algorithms.  The Lagrangian  method
describes the motion of  air parcels by  specifying a
conceptual  "parcel or volume of air" and tracing its
motion  over time.   These  methods  assume  linear
chemistry.   That  is, they assume that  the rate of
change  in  the concentration of  a given pollutant is
directly proportional to the local concentration of  that
pollutant.   Such methods  do not work  well  when  the
reaction rate for the pollutant of interest is affected by
other factors (e.g., other pollutants) and is, therefore,
non-linear.

      Eulerian (fixed  coordinate) methods of describing
air transport will work much better for  EPA's regional
photochemical  transport  model.   Eulerian  methods
describe the motion  of  air  by  specifying  the  air's
density  and  velocity  at a  grid of points in space  at a
particular time. The Eulerian methods can include the
non-linear  chemical calculations needed to predict the
downstream  reactions that form ozone,  sulfates and
nitrates.   The  methods also are applicable  to  long-
range, or regional,  transport.  EPA's research program
will develop the Eulerian framework of the models and
will integrate it with the chemistry modules.

      At the same time, data will  be collected to verify
dispersion   coefficients   interpolated   from  earlier
empirical, limited-situation studies. This verification is
necessary because  the earlier studies were  so limited
that  generalizations  may   be  inaccurate;   also,
meteorological  parameters  work  best  under  stable
weather  conditions and are less accurate for unstable
(strongly convective) conditions.

      Model  development  and verification will depend
upon  data  collected  during  the  Northeast  Regional
Oxidant  Study (NEROS)/Persistent  Elevated Pollution
Episodes (PEPE) program.   The  regional-scale  model
will be tested and refined  using this field  data.  A few
European countries have expressed interest in using the
models and adapting them with their data base.

      The  regional  photochemical  model  will  be a
reactive model. That is, it will be capable of handling a
number   of  different  complex  chemical   reaction
mechanisms  for ozone and  particulate matter.   The
model's  1983 version will address only ozone chemistry.
Following that, the model  will be developed further to
include  reactions of  SO~  to  sulfate,  including liquid-
phase reactions. At a later date, nitrate chemistry will
be added to the model. A  field-evaluated model should
be available in 1986.

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     Urban-scale models  will also be developed.  The
urban-scale  models  that predict the concentrations  of
photochemical  oxidants   in  urban  air  are  of  two
completely/different types.  One  urban photochemical
model  is based  on  the   empirical  kinetic  modeling
approach (EKMA), much of which is derived from smog-
chamber  studies.     By   specifying   amounts   of
hydrocarbons and NO/NO, in  the urban atmosphere, the
EKMA will estimate the level of air pollution controls
needed to achieve the ozone air quality standards.

     The other type of models — air quality simulation
models  for urban photochemicals  and particles — not
only provide  estimates  of  concentrations, they also
predict  the  time-varying  rate of  transformation and
dispersion.  These models  use more advanced chemistry
and meteorology than does the empirical  model.   Most
of the research  to  date has  focused on developing and
validating   first-generation  air   quality   simulation
models.     The   models   were   tested  against   a
comprehensive air  quality  and  emissions  data  base
obtained through a five-year  regional air pollution study
conducted in the St. Louis area during the  mid 1970's.

     EPA's  research program  is  refining both of the
modeling approaches.  Comparisons  of several methods
to predict atmospheric chemical reactions showed large
discrepancies  when existing  ozone and NO   predictive
models  were  run with low HC/NO   ratios, suggesting
that  current  chemistry   submodules  may  result  in
erroneous ozone predictions  and could introduce errors
when used in either the EKMA or air quality simulation
models.

     To  resolve these  problems,  EPA  will conduct
indoor and outdoor  smog chamber  studies, and the data
obtained  will be used to develop  improved chemical
submodels of photochemical smog  formation.  Indoor
smog  chambers  will  be  used  to  investigate  the
photochemical reactions  of aromatic hydrocarbons and
their oxidation products.  Outdoor  chamber studies of
synthetic volatile organic compounds  (VOC), and NO
and NO2  mixtures  will  investigate  the  effects  of
hydrocarbon composition  changes on the formation of
O,  and  other  oxidants.    Multi-day irradiations  of
complex  VOC/NO   mixtures will assess the  oxidant-
forming potential of "spent"  air masses and provide the
necessary data for use in a regional oxidant model.

      This research will  produce chemical kinetic data
for use in either EKMA or air quality simulation models
and a validated O3 and NO2  chemical module in EKMA.

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                         Air
An  evaluation of EKMA  models  using  improved O-,
chemistry will be available in 1984.  Another significant
research output will provide the EPA regulatory office
with regional  photochemical modeling results based on
target emission reduction  strategies provided by the
Office of Air Quality Planning and  Standards.  These
results will be available in 1986.

      At present, sulfate is the only chemical species
that  will  be .modeled  explicitly.    The   chemical
composition  of  other particles Will be addressed as
regulations require.

      Research will also  lead to validated models which
predict  one-hour,  24-hour,  and yearly average values
for  urban  particulates and  the contribution  to  these
values of  plumes  from  large sources  at mesoscale
distances (0-300 km).   An  operator's manual will be
produced for using  the Particulate  Episodic  Model
(PEM) and the point-area-line model in urban situations.
An  improved  urban and mesoscale  particulate model
will  be  produced for state  and local governments and
industry  for use in SIP revision based upon the proposed
new  particulate  standards.

Issue: How can air quality models reflect complex
terrain conditions?

      The Clean Air  Act Amendments of 1977 require
EPA to specify  the  use  of  dispersion models  pertinent
to  prevention  of   significant  deterioration  and  to
attainment of National Ambient Air Quality Standards
(NAAQS).  However, no adequate  model has  yet  been
developed  which  adequately  describes  dispersion in
complex terrains.

      EPA   research  will   develop  such   modeling
capabilities.   Initial model  development  will  use  field
measurement  data  and  results from the  EPA   Fluid
Modeling Facility (FMF) to provide modifications to
models   currently  used  in  the  regulatory  process.
Concurrently, atmospheric  dispersion models will  be
improved.   Field research  will  include tracer studies
over moderately-sized terrain obstacles and a full-scale
plume study  at  an existing power  plant  in complex
terrain.  These studies will  provide data  for evaluating
the performance of  dispersion models under conditions
that cannot be adequately simulated in the FMF.

      Subsequent research will  evaluate the feasibilities
of transferring  the  models to  settings of  increased
topographical complexity, applying  the models during
neutral   or  unstable  conditions, and projecting  the
calculated  one-hour  concentration to three- and/or 24-

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hour average concentrations.   Coordination and  data
exchange will be maintained with similar studies being
performed by the  Department  of  Energy  and  the
Electric Power Research Institute.

     If  the  development effort  is  successful,  an
evaluated  complex  terrain model, including a  user's
guide, will be published in 1985.

Issue: Can sources of pollution be identified by the
unique properties ("fingerprints") of their pollutants?

     Air pollution samplers in current use can detect,
identify and measure the amounts of different airborne
compounds that are deposited on the collection grids;
the samplers and analytical   procedures  used  cannot
identify   the  sources  of the  compounds.    Now,
technology  and  procedures are  being  developed  to
identify the sources  of pollutants.  The identification is
based upon unique chemical signatures of the collected
compounds.      The   concept    is   called   source
apportionment.

     Source    apportionment   works   by   analyzing
collected  particles  with   X-ray   diffraction,   ion
chromatography, neutron activation, scanning electron
microscopy  and  other  advanced  chemical analysis
techniques.  If the particles in question have the same
unique features characteristic of particles found only at
certain  sources,  then the sources  of the  particles in
quertion can be identified.  Currently, the methods are
sufficiently advanced to be able to  identify particles
emitted  by certain  industries but  not  from any  one
specific  plant within a group of similar  industries.  For
example, particles from quench towers of  steel mills
have  unique  chemical  signatures,  but the methods
cannot  tell  which quench tower  produced  a certain
particle.   At  present, source apportionment methods
are limited  by scant emissions data for  determining
industrial  source  signatures.    Both  collecting  the
requisite emissions  data  and  verifying the  chemical
analyses and signature matching methods are important
parts of this  EPA research  effort.

     Source apportionment cannot, by itself, be used to
predict  air pollution concentrations.  By integrating the
apportionment data  with  urban particulate  dispersion
models,  however,  a  hybrid  model  may  be able to
identify sources or, as  the case  may  be, to predict
pollutant types and concentrations at  given urban areas
under differing conditions. In 198^, EPA will use data
collected  in  Philadelphia   to  develop  such  a  hybrid
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model.   The  immediate goal  of  the research  is  to
develop and test a comprehensive receptor model for
apportioning  particulate mass  to  components  from
emissions sources.

Issue: What are the health effects from exposures to
combinations of pollutants?

     In breathing the air, people are often exposed to a
predominant  single pollutant, but at  other times they
may be exposed to a  mixture of compounds, some of
which  may be  harmless, others hazardous.   Health
effects  research, therefore, is expanding its  scope to
consider  multi-agent   exposures  including   potential
synergistic or antagonistic effects in addition to single-
pollutant effects. Depending on the findings, it may be
more   appropriate    to   consider   regulation   of
combinations of pollutants.

     EPA   has  almost  completed   single-pollutant
clinical  research on   non-sensitive  populations,  and
emphasis for studies on normal subjects is being shifted
to multi-agent studies.

     The research is  being conducted simultaneously
with exposure assessment studies so  that health  risks
can be  better defined;  however, because the exposures
are yet to be determined,  in many cases, the effects
research  does   not   yet  replicate  actual   ambient
conditions.  In lieu of  that  approach,  the effects work
will continue to expose volunteers and animals to  single
individual pollutants (e.g.,  O,, NO-,  SO,, or  particle
aerosols) and then to the pollutants togetner in various
ratios.

     As exposure  assessments  produce results  more
representative of actual population exposures, attempts
will  be  made   to re-design  multi-agent clinical  and
animal  experiments  for  exposure   to  air  pollution
mixtures  more  characteristic  of  ambient  conditions.
(There  will  probably  not  be  a  direct   one-to-one
correspondence   of  data  from  this  research   with
epidemiological  studies  due to  the  fact  that  exposure
conditions   for   epidemiological studies  cannot  be
controlled  as can the laboratory work.  Nevertheless,
the object  of these studies is to make such correlations
as meaningful as possible.)

     A multi-year epidemiology study to determine the
health  effects  of  fine particles  will  be  considered
following analysis of a problem-definition study by the
University  of Pittsburgh Center.
                       97

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                         Air
Issue:  What is the cost of damage to crops from air
pollution?

     Reduced yields of crops and forest species have
been observed as  a result  of  air pollution.   These
reductions  are  known  to  adversely  affect  wildlife
habitats  and  human welfare, but the  extent of  the
effects from lost crop and forest productivity have not
yet been quantified.  EPA has initiated  a high priority
research program  to measure the economic losses from
air  pollution, with  its  primary  focus on  agricultural
productivity.

     The research  receives  considerable involvement
from concerned state and  local governments, several
federal  agencies   and   departments  and  from   non-
government research organizations.  The research will
assess  the economics of ozone  pollution so  that  the
benefits  of  air  pollution control to  crop productivity
can  be evaluated.  Data for the  research will  come
from  the  National Crop  Loss  Assessment  Network
(NCLAN), a national program begun by EPA in  1980.

     Since  ozone  is believed to  cause the  greatest
damage  to  vegetation,  the  program  will continue  to
evaluate the impacts of  ozone pollution through field
research conducted at six regional sites.  Crop cultivars
typical of a region are exposed to ozone concentrations
that span the range of air quality conditions and to a
background level that provides an experimental control.
Open-top chambers are used in  this research, because
they are the most thoroughly  tested  field  exposure
systems  and  permit  the  best  control of   pollutant
concentrations under field conditions.

     Results  from  field investigations will  form  the
basis for the construction of  dose-response  functions,
which    relate  crop   yield  effects   with  various
concentrations  of  ozone.      Various   types   of
mathematical   regression   relationships  are   being
formulated,  including a  linear approach  and  a  more
complex  relationship   which  assumes  a  threshold
concentration.    Dose-response  information   will  be
integrated with crop yield data  and ozone  air quality
estimates gathered from  counties across  the United
States.  In 1984, this information will be used  to provide
a national assessment of the economic impacts of ozone
on  the productivity of  major crops.  Field research  is
planned to cover about  90%  of the crop acreage in the
United States.

     Research is  also  planned to  quantify the role of
soil moisture as an influencing factor in  the response of
crops to  ozone and to evaluate the effects of high level

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                         Air
episodes and  of low-level chronic conditions.   Since
these factors are highly important in the response of
crops to ozone, they will be evaluated  to  provide a
more quantitative economic assessment.

Issue: What are the most effective emissions reduction
technologies for volatile organic compounds, nitrogen
oxides and other air pollutants?

      Control  technologies either  remove  air pollutants
or reduce their formation by process modifications.  At
present, engineering  knowledge is available to provide
the necessary technologies, but capital outlays for air-
pollution   control  are  significant  burdens   to  many
industries.  Thus the determination of the  least-cost
option for  controlling air pollution is an urgent goal  for
ensuring a  clean environment and  helping  to maintain a
strong national economy.

      Priorities  for this research  are shifting to focus
on   volatile  organic  compounds,  including   those
designated as  hazardous.   Emphasis on  conventional
pollutants  (sulfur oxides, nitrogen oxides and particles)
is  declining.  In addition, large-scale demonstrations of
emissions reduction technologies  are  being phased out
in favor of less costly  fundamental studies,  pilot and
prototype  testing  and  evaluation,  and  technology
transfer.

      For  the oxidants,  research  will be initiated to
determine   the   least-cost  control  alternatives   for
volatile organic compounds (VOCs)  and nitrogen oxides
(NO and  NO2)> which  are the  major  precursors  of
oxidants such as ozone.

      In widespread areas of the  country, VOCs are a
major cause of  the non-attainment of the NAAQS  for
ozone.  Scientifically valid data  bases, methodologies,
models  and  control   technologies  needed to control
VOCs will  be  provided by EPA's research  to regulatory
decision makers; enforcement  officials; state, regional
and  local  officials;  and  the regulated community.
Control technology such as industrial flares, capture
systems, carbon adsorption,  catalytic  oxidation,  and
thermal  oxidation   will  be  assessed   to   establish
performance standards for new and existing sources of
VOCs.   New source performance standards  now  in
existence will be reviewed and updated by EPA based
on the  best engineering  information  that is currently
available.  The main  emphasis  of this research program
will  be on providing to  industry  cost-effective  and
energy-efficient control alternatives that  will  meet the
standards.
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                         Air
     To  control  nitrogen  oxides,  research will  be
conducted to determine combustion modification (CM)
methods for reducing NO  emissions and for  improving
the performance of industrial furnaces.  Prior work  on
utility  boilers  has  proven  that  CM  methods can
effectively  control NO  as well  as  other  emissions.
Future research effortsxwill tailor CM methods to the
characteristics •  of the  many types of  furnaces,  e.g.,
stoker boilers, steamers, package boilers, cyclone, wall-
fired burners and heavy oil burners.

     Research will also develop  a technical  basis for
estimating  the  lowest  achievable  nitrogen  oxides
emissions   from  current   and   future  combustion
equipment  and   fuels.    This  research  will  support
technology  developments  and enforcement  activities.
Emission  reduction methods  from  stationary internal
combustion  (1C) engines using fuel modification and  oil
or exhaust gas treatment will also be assessed.

      For controlling  gases and particles, research will
test the electrostatically enhanced fiber filter  (ESFF)
technology to define cost-effective means of applying
baghouses in conjunction with dry-SO2 systems.  SO
removal with this technology will provide an alternative
to costly wet flue-gas desulfurization (FGD) systems.
Further  research will  develop a better fundamental
understanding of the  operational characteristics  of
devices, processes and materials  for  controlling gases
and particles.

      The  shift  of   electric  power  utilities to  dry
scrubbing for  low-sulfur  coals  requires performance
tests using varying coal types as a prerequisite to NSPS
revisions. Assessments will also explore the  feasibility
of   combining   several   controls,   including   coal
preparation, for  obtaining  more effective   pollutant
removals.

      Electrostatic  precipitator   (ESP)  research  to
define the  mechanisms and  principal parameters for
two-stage ESP  operation  with low-sulfur  coal  fly-ash
will  be  completed  in  1983.    Using comparative
assessments, design parameters for two-stage collector
stages will be defined.  A design report will be produced
to assist vendors and  users to adopt this lower-cost ESP
technology.
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    Chapter Six
ACIDIC DEPOSITION

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ACIDIC DEPOSITION
Outline:
Introduction
Legislative Mandate
Background
Major Research Issues
     Issue:  What are the relationships between sources
     and receptors?
     Issue:   What are  the quantitative relationships
     between  acidic deposition  loadings  and  their
     effects?
     Issue:  Has acidic deposition been increasing?
     Issue:  Is  liming of acidified lakes cost-effective?
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                  Acidic Deposition
INTRODUCTION

      The   term   "acidic   deposition"  means   the
atmospheric  deposition  of  acidic  or  acid-forming
compounds  in  either  their dry  or wet form.  These
compounds exist in the atmosphere as gases or aerosol
particles.  The gases are sulfur dioxide  (SOA nitrogen
oxides (NO  ) and hydrogen chloride (HC1).  The aerosol
particles  a?e sulfuric acid, nitric  acid (a  gas in the
troposphere)    and  certain   sulfate    and   nitrate
compounds.  While scientists generally agree that these
compounds  are  responsible for  deposition of varying
degrees of  acidity,  there remain major  uncertainties
regarding the causes, extent,  consequences and  cures
for the problem.

      The major scientific issues are:

•     Has acidic deposition been increasing?
•     What source/receptor relationships should be used
to  determine emission control strategies?    Compare
deposition   from    local   sources  with  deposition
transported  from distant  sources?    Determine  the
importance  of acid aerosols from natural sources?
•     What  are  the  quantitative relationships between
acidic deposition loadings and their effects?
•     Is liming of acidified lakes  a promising mitigative
option?

      To  answer these  questions  and   to provide  the
scientific  and  technical  data  that   regulators   and
legislators need for  formulating  policy,  EPA and other
federal agencies  are  conducting  a major  research
program.

      EPA's   program  is   investigating:    (1)   the
relationships between  man-made emissions, precursors,
and acidic  deposition, (2)  the processes influenced by
the  formation  and transport  of  acidic  and acidifying
substances,  (3) the  deposition of acidic substances on
terrestrial  and  aquatic  systems,  and  (4) effects  of
acidic deposition  on  aquatic environments,  drinking
water, agriculture, natural terrestrial ecosystems  and
materials.  The  program  will provide  assessments to
support  policy  analyses  that  determine   the  cost
effectiveness of potential control strategies.

      The acidic deposition  research program for fiscal
year  1983 is allocated $12.5  million, which is part of
the $22.3 million budget  of the Interagency Task Force
on Acid Deposition.  EPA's resources are divided among
the  programmatic categories of  the  interagency  task
force  as  follows:  man-made sources, $1.1   million;

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                  Acidic Deposition
atmospheric   processes,   $3.9   million;   deposition
monitoring, $1.6 million; aquatic impacts, $1.9 million;
terrestrial impacts, $1.5 million; effects on materials,
$0.4 million;  and assessments and policy analysis, $2.1
million.

LEGISLATIVE MANDATE

     EPA's program is a component of, and operates in
cooperation   with,  the  National  Acid  Precipitation
Assessment Program (NAPAP), established by  Congress
in 1980 under the Energy Security Act.  Management of
the  NAPAP   research   is  being  handled   by  the
Interagency Task Force on Acid Precipitation, which is
jointly chaired by EPA, the Department of Agriculture
and    the   National   Oceanic   and   Atmospheric
Administration, and includes research representatives
from  those  agencies  and from the  Departments  of
Interior,   Health  and   Human   Services,   Energy,
Commerce,   State,  the  Council  on Environmental
Quality,   the    National   Aeronautics   and   Space
Administration, the National Science  Foundation  and
the Tennessee  Valley Authority.  The  federal research
program  has a  ten-year legal mandate. It oversees all
federally funded acidic deposition research  projects.
EPA has a  coordination  role  in  the  task  groups for
aquatics, control  technology,  and  assessments  and
policy  analysis.  EPA also has a major research program
to  study     man-made  acidic  deposition   sources,
atmospheric   processes,  deposition   monitoring  and
terrestrial and  materials damage.

BACKGROUND

     Acidic  deposition  has most likely  occurred in
cities  for several centuries.  It was first described by
Robert Angus  Smith  in Manchester, England, in 1853.
In the  United States, acidic  precipitation (snow, sleet,
rain, hail) has been  measured over a large portion of the
eastern states for the past 25 years.

     The formation of  acidic deposition  begins when
atmospheric  SO, or NO , as  either   gases  or  liquid
droplets, are  oxidized by other airborne chemicals to
become  sulfate and nitrate  aerosols or gaseous nitric
acid.  While  these  atmospheric  transformations are
thought  to  account  for  the  majority of the  acidic
compounds,  some acidic aerosol particles are emitted
into the  air directly from power plants, automobiles and
other man-made sources.

     Once formed, acidic gases and  aerosol particles
can be removed from the atmosphere by either rain,
snow or  fog, resulting  in acidic  precipitation.   Such
atmospheric   removal   processes   are  referred  to

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                  Acidic Deposition
collectively as "wet deposition." If there is insufficient
moisture   for   precipitation   to   occur  the   acidic
compounds, including  SCX  and NO   not  oxidized  to
aerosol particles, can settle or diffuse to the earth and
be  deposited  in a  dry form,  eventually  oxidizing  or
combining  with  water (and also oxidizing) to produce
sulfuric or nitric acid.  This phenomenon is called "dry
deposition."

      Atmospheric SOj and  NO come from man-made
emissions  as  well  as from   natural sources.   The
chemicals  which serve as efficient oxidizing agents in
the atmosphere  primarily are  believed to come from
photochemical   reactions  involving  volatile  organic
compounds (VOCs) and NO .

      Estimates  of man-made  SO- emissions show that
65% of U.S. emissions come from  electric  utilities and
the    remainder   from    various    industrial   and
transportation sources.  Estimates of man-made NO
emissions in the  U.S. indicate that more than 40% come
from transportation sources, 30% from electric utilities
and the remainder from other types of combustion. The
primary   man-made   sources   of   volatile   organic
compounds are automobiles, processes that use solvents
and facilities for fuel production and distribution.

      The  natural   sources  of  atmospheric   sulfur
compounds  include  marine bioactivity,  swamps and
volcanos.  Estimates  of  the   global  sulfur  compound
emissions from these sources are  comparable to  those
for man-made sources, although  man-made processes
are  responsible   for  the  dominant  portion  of  $©2
emissions in industrialized areas such as eastern  Nortn
America.

      Estimates  of global NO  emissions from natural
sources (microbial activity in  soils, burning of forests
and agricultural residues, and lightning)  are  much less
certain than are the  SOj estimates.  Current global
estimates indicate natural NO   emissions  to be of the
same magnitude as emissions Irom industrial  sources.
For   the   United  States,  however,  industrial   NO
emissions are roughly estimated to be  ten times greater
than natural emissions.

      The  amount   of  volatile  organic   compounds
emitted from  natural  sources  is also uncertain.  The
role of natural emissions in the regional formation  of
oxidizing agents  may or may not be significant.

      Whether natural or  man-made, all acid-forming
compounds  and  aerosols  can  be   atmospherically
transported for distances of a few to  many hundreds of
kilometers  from their point of  release to  where  they

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                  Acidic Deposition
return to earth as wet or dry deposition.  If deposited in
the   sea,   the   acidic   aerosols   and  acid-forming
compounds  are  probably  rendered   harmless.     If
deposited on land, however, the compounds may or may
not cause an adverse effect, depending upon the nature
and sensitivity of the receptor.

      The effects of acidification on aquatic life have
been  demonstrated,  to some  extent,  in  the  field.
However, the  extent to which these effects are caused
by  acidic  deposition  has  not  yet  been  rigorously
determined.  Quantification of these and other effects
on  susceptible lakes  and  streams  is currently under
investigation.  Aquatic effects can manifest themselves
as  changes in the  life  forms  found   in the water.
Fishless lakes, for example, can occur when a lake's pH
falls below  5 (note: the  lower  the pH,  the greater the
acidity;  a  pH  of  7  is neutral).   Several  reports,
scientific studies and surveys conclude that a number  of
lakes in  North America have been  affected by acidic
deposition.   On  the  whole it  appears that  a  small
percentage  of  lakes  or  lake acreage  may  have been
significantly  affected   to  date.    Some  scientists,
however, express concern that present deposition levels
of  acidic  and  acidifying  substances  may  cause
additional aquatic systems to become acidic.

      Acidic deposition  may also affect forests, crops,
soil systems, drinking water,  man-made materials and,
indirectly, human health. Scientists are now seeking to
quantitatively determine if, and to what  extent, such
effects  occur.   Because  of  the  complexity  of the
natural systems involved, however, decisive answers are
difficult  to come by. For example, after  more than a
decade of investigations, Scandinavian researchers still
find it difficult to demonstrate  conclusive cause-and-
effect relationships  between  acidic  deposition and
forest productivity.

      Studies  of  acidic  deposition  effects on natural
terrestrial ecosystems have shown limited evidence  of
damage.   While acidic deposition may  subtly influence
the functioning of  terrestrial ecosystems, potentially
harmful effects may  be obscured in the short term  by
nutrient   enhancement   from  sulfates  and   nitrates.
Recently, however, declines in the productivity of some
forest systems have been noted, although the cause  for
the declines remains unclear.   Therefore,  a primary
concern   for   research   study  is   the   long-term
implications of acidic loadings to natural systems.

      Few   studies   have   demonstrated  that  acidic
deposition  either increases or  decreases  crop  yield.
                        106

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                  Acidic Deposition
Nutrient enhancement, again, tends to cloud the issue.
One recent report states  that  a decrease in soybean
yield may occur at ambient levels of acidic deposition.
However, because plant responses  to acidic deposition
(in either natural or managed systems) depend on many
variables such as soil condition, species sensitivity, life
stage,  other  air  pollutants  and  drought,  no  major
damage  to plant  productivity  has  been  specifically
attributed to  acidic deposition.   Some  researchers
theorize  that responses to acidic  deposition may be
occurring but that the responses are being masked by
the complexity of the affected ecosystems.

     The direct risk to humans from acidic deposition
is believed to be very low.  The pH of acidic deposition
is generally well within the range normally tolerated by
human skin and gastrointestinal tracts.  Indirect risks to
humans which might come from drinking water and food
contaminated by acidic  deposition are also quite low,
except where untreated cistern or well  water are used.
For example, while acidification of plumbing pipes can
cause lead and copper to leach into cisterns, untreated
well  water   and   drinking  water,  most  urban  and
municipal  water  systems control pH levels to reduce
such corrosion.  Surveys will  indicate whether pH is a
problem  in smaller systems.

     Acidification can  also release heavy metals such
as  mercury   and   cadmium  from  lake  and  stream
sediments making  them available  for  uptake by fish.
These heavy  metals, it is theorized, may accumulate in
fish tissues which  may, in turn, be consumed by humans.
Although such effects  could occur, current evidence
does not  indicate that  acidic  deposition  is a  human
health problem.

     Among the many  research projects that are  part
of the federal acidic deposition research program are
several  that  address   the  entire  range  of  acidic
deposition issues.  Two  such projects are part of EPA's
program.  The first involves  production  of  a major
report summarizing the state of scientific knowledge
with regard  to all aspects of acidic deposition.   This
critical assessment of the acidic deposition phenomenon
will be published in 1983.   The second  project involves
completion of an  integrated  cost-benefit assessment
framework for  linking  emissions models, atmospheric
models  and  effects  relationships.   This  framework,
intended for use  in policy-related  studies, will be
available in 1986.
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                  Acidic Deposition
MAJOR RESEARCH ISSUES

Issue: What are the relationships between sources and
receptors?

     The atmospheric chemistry  processes  that  form
acidic deposition are being studied in order to develop
source/receptor relationships.  Through mathematical
modeling   and   other   means,   quantification   of
atmospheric processes will help scientists to understand
several key factors.  For instance, scientists know that
the  presence  or absence of certain oxidants, other
chemicals,  moisture  and particulates  influence  the
conversion of  SO- and  NO  to atmospheric acids, but
the complex interactions of all these elements have yet
to  be  unravelled.   Likewise,  ozone  and  hydrogen
peroxide are known to play a significant role in the
formation of oxidants,  but their actual effect on the
conversion has yet to be determined.

     Another    major    requirement   for    defining
source/receptor relationships is the identification and
measurement  of  factors  that  control  atmospheric
transport of acid-forming compounds and aerosols.  The
intricacies of  meteorological mechanisms,  which are
just beginning  to be  understood,  make  it difficult to
specify  the  atmospheric paths along which compounds
may be transported.

     As part  of EPA's  research effort,  large-scale
meteorological models are being refined.  One  current
shortcoming is  that the models assume that the rate of
conversion of  sulfur and nitrogen  compounds to acidic
compounds   is   proportional   to   their   respective
atmospheric concentrations — in other words, the more
SOj present in the atmosphere, the  more acid sulfate
produced. Theory and experimental evidence show that
this assumption may be too simplistic to describe actual
photochemical  conversion  rates.    Because  of  this,
models   are  now  being  improved   to  include  the
influences of the mix of oxidants, chemical competition
for  oxidants,  and  the   presence  of  aerosols  and
particulates to  act as  reaction  sites.    The  refined
models will  also be designed to more  accurately reflect
the  vertical transport of compounds between  various
layers of  the atmosphere  than  do  current  models.
Horizontal transport  rates,  and  hence  the  extent of
dispersion,  depend  in  large  measure  upon  vertical
exchange rates.
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                  Acidic Deposition
      Another problem  with using existing models  to
differentiate between deposition from local  and long-
range sources is that calculations for sulfur compound
deposition  are far  more developed than  are  those for
nitrates.   In some areas, locally  produced  nitrogen
oxides may make an important  contribution to acidic
deposition.

      Finally, long-range transport models only indicate
the contribution  of emissions  from  geographic areas;
they  do  not  indicate those from individual sources or
types of sources.  Thus, the models cannot differentiate
among emissions  from  utilities,  industries,  homes  or
automobiles.  Until refined to do so, their usefulness,
especially in formulating and testing  control strategies,
is limited.

      In  1983 EPA, NOAA,  DOE and TVA will begin
field studies and the development of better  atmospheric
models  to  provide  more information about  long-  and
short-range acidic deposition transport and  the relative
importance of wet and dry deposition.  An  inventory of
acid  deposition   precursor  emissions  data  will   be
developed  to support the modeling  research.   Model
data  will  also help to determine  oxidation  reaction
pathways and atmospheric oxidant concentrations.

      Building  upon the  results  of this  research,
numerical    transport   models   are    expected   to
demonstrate  improved  source/receptor   associations.
The research will  include models for examining long-
range transport   and   regional  aspects   of   acidic
deposition  and a comprehensive field study of  source-
receptor relationships using atmospheric tracers.  These
results will be available in  1986 and 1988.

      Among the other major planned research products
associated  with this issue are:

•     Produce a  completed  electric utility simulation
model for emissions forecasting for use in 1985.
•     Provide  a   comprehensive  emission  inventory
system by  1985.
•     Complete  an  industrial  simulation  model  for
emissions forecasting in 1985.
•     Produce a report  in 1986  to define  the  relative
importance of deposition from local sources.
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                  Acidic Deposition
Issue:  What are the quantitative relationships between
acidic deposition loadings and their effects?

     By studying the physical, chemical and biological
characteristics of lakes, streams  and watersheds  and
the relationships between amounts of acidic  deposition
in  a watershed  and  the  pH levels  in  an  aquatic
ecosystem,  EPA  research  will seek to quantify  the
relationship  between  acidic  deposition  loading  and
ecosystem effects.  One of the  main  problems facing
this effort results from dramatic local  variations in the
buffering capacity of watersheds.

     The buffering capacity of a lake and its watershed
are the main factors in  determining a lake's ability to
neutralize acidity.   Sensitive aquatic  systems have
•watersheds with little or no neutralizing capability in
the  soils  and bedrock.   As  a result, such systems have
insufficient means to neutralize incoming acids.  Areas
suspected to  be  sensitive  are  generally mountainous,
with shallow soils underlain by granitic bedrock.  Such
areas include portions of New York, the New  England
states,  the Appalachians,  the Ozarks, the Rockies,
Sierras, and Cascades, the provinces of Ontario, Quebec
and Nova Scotia, and  mountainous areas  in  western
Canada.

     Buffering  capacity  varies  with  the   nature of
underlying rocks, surrounding soils and vegetation  in the
watershed.   Lakes  in  watersheds  with low buffering
capacity may become acidified, while lakes in the same
region  with  watersheds  having  a  higher  buffering
capacity, may not.  The Adirondacks, southern Ontario
and Nova Scotia are the main regions where some lakes
are believed to show the greatest effects from acidity.
In addition, areas of the Southeast and Upper  Midwest
are also  sensitive  to acidic  inputs due to the  poor
buffering capacity of the soils in these  regions.

      Many  lake features  influence susceptibility to
acidic deposition.  A lake's size and depth,  its rate of
"flushing" (water flow through) and whether  it is fed by
surface  water or  ground water all help to determine
how it responds to  acidic  deposition.   Lakes that are
poorly buffered and unable to  neutralize much  acid are
particularly susceptible  to  surface water inflows with
low pH's.  Surface water with a low pH can be caused
by  acidic deposition, land use practices, natural "humic"
processes or a combination of all  three.  A dramatic
decrease in a lake's pH can occur in  the spring when
acids accumulated in the melting snow flow  into a lake.
This episodic phenomenon, known  as "spring  shock," can
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                  Acidic Deposition
deplete fish populations and the lake's pH can decrease
quite drastically.   Weather  patterns  also play a role.
Local air turbulence  and eddys of rain and snow over
hills and mountains contribute to the local variability of
acidic deposition impacts.

     The manner in which land is used in watersheds is
also an important  factor contributing  to potential lake
acidification.   Logging  may  be important  because it
causes  a dramatic shift  in  an  ecosystem's nutrient
cycling.    Around  populated  lakes,  effluents  from
residences may neutralize some lake acidity.

     To determine the  extent and magnitude of lake
and  stream acidification  and  the  associated loss  of
commercially  important  fish the EPA, the  Departments
of  Interior, Agriculture  and  Energy,  the   Tennessee
Valley   Authority,  industry  and  several  states  are
cooperating in a major research program.  One goal of
the program  is  to  develop a  national inventory of  the
impacts  of acidic  deposition on the quality  of surface
waters,  including  drinking  water.    Another  goal,
scheduled for  completion in 1983, is the preparation of
regional  and national tabulations and maps showing the
distribution of acidified, and acid-sensitive, waters. By
comparing historical water quality data with  watershed
studies, the research  will assess the rates  of change in
water  chemistries  and  thus provide  information  for
evaluating future water  conditions.  Field surveys will
be added in 1984 to inventory the biological  impact of
acidification on fish.

     Correlations among research results will help to
reveal  the causes, as well as  the extent,  of altered
aquatic systems.  A  major assessment  of atmospheric
deposition loading limits  for aquatic ecosystems effects
will be published in 1985. Reports to assess damages to
aquatic ecosystems in physical and economic terms will
be published  in 1986  and  1988.  Another assessment,
this  one of terrestrial effects in economic  terms, is
scheduled for  1985 with updates in 1987 and 1989.

Issue: Has acidic deposition been increasing?

     Regardless of where  acidic  deposition  has been
observed and  measured, there  is  insufficient evidence
to state  with certainty that the acidity of  precipitation
is  increasing  in North America.   Historical  data  are
simply too meager.   Useful historical data  could be
gathered  from glaciers  and ice fields  of the Arctic,
Greenland,  the   Antarctic    and   high    mountains.
Theoretically, snow and ice core samples  taken from
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                  Acidic Deposition
the ice masses should contain a record of the trends in
the chemistry of acidic deposition. From those records
scientists should be able to determine patterns of acidic
deposition  over  hundreds of years.  To  date, however,
the  few efforts  to  detect  such patterns have  not
produced  definitive  results.    One  key  problem  is
determining whether the  acidity in the  samples comes
from man-made sources  or  from  natural processes.
Preliminary results from studies of glaciers do indicate
that SO. and metals deposition have increased since the
industrial revolution.

     Historical  records about U.S. air quality are also
inadequate  for   establishing  scientifically  rigorous
trends    regarding   atmospheric   acidity   or   the
concentrations of precursor chemicals.  In this case,
there  is  a  need  to  understand natural  cycles,  or
geocycles,  to avoid misinterpreting  "apparent" short-
term trends.

     In  Scandinavia,  where  acidic  deposition  data
records are  more  complete  than in North America,
analyses   suffer   similar    shortcomings.      Strong
correlations  found  between  the  concentrations  of
sulfates and nitrates in precipitation  and  precipitation
acidity are not reproducible when sulfur emissions data
are  collected from arrays of monitoring stations over
extended time intervals.  The differences in correlation
between concentrations  and emissions  may   reflect
year-to-year  variations   in  atmospheric  transport
patterns or the complexity of  atmospheric mechanisms.

     EPA  and  other  federal agencies are currently
gathering  data  to  determine   acidification   trends.
Effects studies  include the examination of tree rings,
lake   sediment   cores,   acidification   damage   to
tombstones,  and   an  analysis  of  historical   acidity
measurements.    To gather  precipitation  data,  EPA
participates  in  the National Trends  Network (NTN)
which will  have 150 precipitation chemistry monitoring
sites in  the U.S.   Presently, EPA also  supports the
National Atmospheric Deposition Program (NADP), a
federal,  state and private  program that operates 110
monitoring  sites,  most  of which will shortly  become
part of the NTN when the two programs merge.  EPA is
also cooperating  with  other agencies  in  initiating a
research program  to quantify dry deposition loadings in
the U.S.

     An  assessment  of  forest  effects  from acidic
precipitation  using tree  ring analysis is due  in  1984.
Similar assessment reports  of  effects on man-made
materials and cultural resources will be  available in
1985 and 1989.

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                  Acidic Deposition
     Among  the  major  planned  research  products
related to this issue are:

•    A   major    evaluation    of   dry   deposition
measurement  techniques, along with recommendations
for monitoring  network  designs, will  be produced in
1983 and updated in 1985.
•    An  assessment   of  trends   related  to  acidic
deposition  will be published in  1985  and   updated in
1989.

Issue: Is liming of acidified lakes a promising mitigative
option?

     One   suggested   method  for   protecting   and
restoring susceptible lakes  is to add lime  to neutralize
the  acids.    Studies  of  Swedish  lakes  and  streams
demonstrate that adding lime to the water restores fish
habitats,  enables   restocked   fish  to  survive   and
reproduce,  and   causes   undesirable  plant  species
common to acidic  water  to disappear.  However, the
protection of  lakes continuing to receive acidic inputs
would  require periodic reliming, varying from annually
to once every five years.

      The Fish and Wildlife Service of the Department
of  Interior is  working  with  EPA to  conduct  field
research  on lake liming  in North America.   Liming
strategies to protect against "spring shock"  and to trap
metals in the watershed before they enter streams are
being  tested.    Additional liming research  is  being
funded by the private sector and by Canada.

      These separate  research activities will  identify
where  liming  is  practical  and  will quantify  both
beneficial  and  adverse  effects.   A  report  on  the
economic  and  biological  feasibility   of  liming  as  a
mitigation measure will be produced  in  1984.   Final
recommendations on the use of  liming will  be made in
 1986.

       Among the  major  research  products associated
with  this  issue  is the publication of a  cost-benefit
assessment of acidic  deposition  mitigation strategies.
This assessment will be published in 1987 and updated in
 1989.
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Chapter Seven
  ENERGY

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ENERGY
Outline:
Introduction
Legislative Mandate
Background
      —  Synthetic Fuels
      —  LIMB/LOW-NO
Major Research Issues
      Issue:     What  are  the  key  synfuels-related
      pollutants?
      Issue:   What are the  health  and environmental
      risks of synfuel-related pollutants?
      Issue:  What are the reliability and effectiveness
      of   alternative   synfuel   pollutant   emissions
      reduction technologies?
      Issue:   What  is the best approach to monitoring
      synfuel-related pollutants?
      Issue:   How  do boiler conditions influence key
      pollutant-related reactions?
      Issue:  What configurations employing LIMB/Low-
      NO  burners  show promise of reduced  emissions
      control costs?
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                       Energy
INTRODUCTION

     In the  past few years,  adequate energy supplies
and a decrease in the growth  of overall energy demand
have   effectively   reduced   the  short-term   crisis
orientation  of  America's  energy  policies.    These
developments are reflected in EPA's energy research
program.  The program has been  reduced in scale, its
efforts have been more clearly focused and the timeline
for results has been extended.  These changes give EPA
an  opportunity  to   help   to  resolve  energy-related
environmental problems at a more considered pace.

     A number of major projects are planned or  under
way and  the  program  is  still  meeting its primary
objective  — to provide EPA offices, federal, state and
local  governments,  and  industry with  the  scientific
information necessary for  producing and using energy
resources  in an environmentally acceptable manner.

     EPA's   energy-re la ted  research  addresses  two
major subjects: alternate fuels (including synfuels), and
limestone injection multistage burner (LIMB)/low NOX
emissions  reduction technologies.

     The  alternate  fuels  program  will evaluate the
transport, fate and effects of pollutants associated with
the production  and  use  of synthetic  fuels, and will
investigate alternative emissions-reduction techniques.
EPA-initiated  research  within   the  synthetic  fuels
industry   takes  advantage   of EPA's  experience  in
analyzing  waste streams,  pollutant loadings, health and
environmental effects, emissions  reduction  technology
strategies, cost/benefit  relationships  and  regulatory
requirements  of various  energy  technologies.    Such
research efforts now will  help to avoid costly  future
corrections   in  the  emerging synfuels  industry by
identifying potential health  and  environmental  risks,
and  by   providing   information  on  the  cost  and
effectiveness  of  pollution  control  strategies before
plants  are  designed  and   built.    To  achieve   these
benefits, EPA plans  to initiate an intensive  program  to
characterize    discharge    and  emissions   reduction
technology in the first large U.S.  commercial  plants
that will start up in  1983 and 1984.  The  process for
permits to build and operate synfuel facilities will be
improved  to  reduce  delays,  and the  technology  to
minimize  the pollutant emissions will be incorporated
at an early stage, not added  on at a later time. In some
instances, the reduction of  pollutant emissions  may
actually improve overall plant efficiencies.
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                       Energy
     The  LIMB/low   NOX  research   will   provide
engineering  and  design   information   for  promising
emission reduction technologies for new and existing
industrial and  utility  boilers.   This information  may
prove  invaluable for  states involved with  the acidic
deposition issue and for plants which may be required to
further  reduce their  air  pollution emissions.   The
energy-related research program for fiscal year 1983 is
allocated $12.5 million. This total is divided among the
major  research disciplines as  follows:  environmental
engineering and technology, 77%; health effects, 19%;
environmental processes and effects, *%.

LEGISLATIVE MANDATE

     Air and water pollutants  and solid wastes result
from the production and use of  fuels.  These pollutants
are   subject   to   environmental  regulations    and
enforcement specified in the  Clear Air  Act, Clean
Water   Act,  Safe  Drinking   Water  Act,  Resource
Conservation  and  Recovery  Act,  Toxic  Substances
Control  Act  and the  National Environmental  Policy
Act.     EPA  research  to  support  regulations   and
enforcement responsibilities is mandated, directly or
indirectly,  by these six federal acts.

     For the synfuels program, EPA is authorized to
provide  scientific information  for the  permit process
and  preparation  of  environmental impact statements,
for consultation with the Synthetic Fuels Corporation in
reviewing new synfuel facilities, for characterization of
the  potential  discharges  and  review  of alternative
methodologies which reduce emissions  and discharges,
for evaluation of the  need for the establishment of
pollution standards,  and as assistance to federal, state,
and local governments and industrial organizations.  In
addition, Section 131(e) of the  Energy Security Act of
1980 directs EPA to provide scientific consultation, on
environmental monitoring technology and procedures,
to synfuel  projects supported  by the  U.S. Synthetic
Fuels Corporation.

BACKGROUND

      Synthetic Fuels:
•     What are  the key pollutants that  result  from the
production and use of synfuels?
•     What are the health and environmental risks of
synfuel-related pollutants and fuels?
•     What are the reliability and  cost effectiveness of
alternative technologies  for reducing  synfuel-related
pollution?
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                       Energy
•     What is the best approach for monitoring synfuel-
related pollutants?

      Research and development planning has begun for
the task  of collecting data on the five  large  synthetic
fuel plants (Great  Plains, Cool Water,  Eastman, Wood
River, Union Oil) expected  to start  up in 1983-1984.
Because  there are no full-scale synthetic fuel facilities
currently operating in the  United  States  (except for
smaller,  industrial low-Btu gasifiers), very little data is
available at  this  scale.    New  pollution  reduction
technologies have been applied only at bench- or pilot-
scale levels.  Some emissions reduction  technology has
been  applied at  full  scale, but adequate  data is not
available and  major problems are known to exist.  In
most  cases, synfuels emissions reduction technology is
being designed by engineering extrapolation from other
industries.

      Given  these limitations, the initial research has
evaluated  foreign  facilities,  and  has  incorporated
laboratory or  pilot-scale  research   results  into  the
development  of  models that  will  provide  data on
expected operations.    Because  the   environmental
control technology for synfuel plants is in an embryonic
state, some  problems may  arise in  relation  to the
effectiveness and reliability of the technology.   These
problems may need to be corrected on a quick-reaction
basis.  As demonstration facilities are constructed and
more experience is  gained  with them, the verification
of initial results will progress.

      EPA has  been  collecting  data  from  its own
research  activities   and   those  of   other   federal
organizations, private industry and foreign  researchers.
These sources have been investigating  the occurrence
and potential effects of synfuel plant pollution for some
time.   Research within the Department  of  Energy
(DOE) addresses reproductive, genetic and carcinogenic
effects  and  the environmental  cycling   of   synfuel
pollutants  in  aquatic and   terrestrial  systems.   The
National Institute for Occupational Safety  and  Health
(NIOSH)   has  conducted some  research into  worker
health effects of synthetic fuel plant  exposures.  Data
from  synfuel plants  in Yugoslavia and South Africa has
also been evaluated by EPA.  These data consist of  a
characterization  of  effluents from a Lurgi gasification
plant and a  study  of  morbidity and  mortality  rates
associated with  specific  plant  operations.   Ambient
monitoring  and   fugitive  emissions   data  are  also
available from the Yugoslavian facility.  These plants
are not  necessarily representative  of the U.S.  plants
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                       Energy
that will start in 1983-1984; both the technology and
the    fuel    characteristics   differ    substantially.
Nevertheless, because they are the only operating data
available,  they  are  being  evaluated to  assess  the
potential risks of operations in the United  States, to
help  quantify  control  levels,  and to help  EPA to
determine whether treatment or removal of potentially
dangerous materials is necessary.

      EPA has  worked  closely with the Department of
Energy in many  areas of synthetic fuels research and
development.   Over the  past several  years, EPA has
gained access through DOE to most of the synfuel pilot
plants, including  Solvent  Refined  Coal (SRC)  I and II,
Exxon Donor Solvent (EDS) and the H-coal plants. DOE
is the operator of these  plants and provides  detailed
analysis of the product materials. EPA has developed
and continues to  improve upon  screening  methodology
applicable  as  an indicator  of appropriate emissions
reduction technology.  EPA has also co-sponsored with
DOE  the evaluation of  a  pilot Stretford (SO   removal)
unit  and  emissions testing  at  the   Department of
Interior's installation at Fort Snelling, Minnesota. EPA
and DOE have also participated  jointly in the Industrial
Gasifier Commercialization Program.   In this program,
which involves the use of  synthetic fuels gasification to
power  industrial applications,  EPA  has  focused on
short-term  source testing, while  DOE has concerned
itself with long-term health effects.

      Another  area  of  cooperation  is  combustion
testing.  DOE makes test fuels available to EPA, and
tests the fuels for combustability and efficiency (heat
content).  EPA's  job is to check the emissions,  compare
them to petrofuel emissions and  test  for  the  presence
of hazardous organics.  In addition, there is coordinated
research  planning  between  the  two   agencies  on
treatability of wastewater from  synfuel plants.   EPA
has also cooperated with  the Department of Commerce
(DOC)  by  providing them with test recommendations.
EPA  is focusing its research and development efforts to
learn how  existing pollution  control devices will act on
synfuel  plants,  and  to   quantify  the  synfuel-based
emissions    by   plant   configuration    and   fuel
characteristics.

      LIMB/low NO :
•    How  do   combustion  conditions   in   a  boiler
combustion zone influence subtle  physical and  chemical
reactions?
•    Are there  LIMB configurations (fuel preparation,
low-NO   burner, particle  collection)  which  show
promise of reduced emissions reduction costs?

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                       Energy
     EPA's  research  is producing  fundamental and
bench-scale  information.   In cooperation  with boiler
and/or burner manufacturers, additional EPA research
projects  will provide prototype-scale information.  To
carry the research one step farther, in cooperation with
foreign efforts (e.g., the Federal Republic of Germany),
the  EPA program  may seek  to  develop  information
relating  prototype-scale engineering  data  with  full-
scale field applications.

MAJOR RESEARCH ISSUES

     The major questions  or issues to  be addressed by
the  synthetic  fuels  and  LIMB/low   NOX  research
programs are:

Issue:  What are  the key synfuels-related pollutants?

     Pollutants  will be  produced at various points  in
the synthetic fuel production and  use cycle.  The types
of  pollutants  and  their   concentrations   will  vary,
depending on the processes used  to produce the  fuel,
plant design  and the use  of  the fuel.   To  develop
adequate   pollutant   reduction    technologies   and
monitoring  plans and to  ensure  that  any  hazardous
substances  are   kept  below  harmful   concentrations,
synfuel process  streams  containing potential pollutants
need to be identified and loadings determined.

     EPA researchers will continue to study pilot-scale
and   full-scale   synfuel   .plants   to   identify  and
characterize plant emissions.  This research, plus any
data collected on the initial domestic plant start-ups in
1983-1984, will be used to assist permit writers in cases
where     similar    feedstocks    and/or    conversion
technologies are proposed.  This will help to ensure the
adequacy  of   environmental   permits and  impact
statements produced for the second wave  of synfuel
plants (those supported by SFC).

     Another major research task is the identification
of pollutants from  synfuel activities.   Of  particular
concern are those polycyclic organic matter  (POM) that
are carcinogenic, reduced sulfur species (some of  which
may be toxic), and hazardous fugitive  volatile organic
compounds (VOCs).  Identification of airborne emissions
will  receive the most  emphasis  because  of  ongoing
research and available test  facilities. Data collected in
field characterization studies will be used as input for
risk assessment studies.
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                       Energy
     Research on synfuels from  coal, peat, oil  shale,
tar sands and heavy oil will target those fuel production
processes which  are  most likely  to  reach commercial
use at  an early  date.   This  effort  will  consist  of
planning and  tracking for the 1983-1984 start-ups, plus
some work on the Westinghouse comparative (synfuels-
to-petroleum)  combustion   testing,  cooling   tower
wastewater emissions and  hazardous  volatile  organic
compounds.

     Pollutants from an oil shale synfuel facility will
be studied either at the  Union B site in Colorado or at
the Chevron  site  in Salt  Lake, beginning  in  1984.
Research  activities  will  include  characterizing  air
emissions and the constituents of wastewater  used to
moisten  spent shale  piles, identifying and measuring
leachate  runoff, evaluating the  physical stability  of
spent  shale piles  and  evaluating the potential for local
vegetation to take up toxic elements  caused by shale
processing.

     Over the next few years, the trend  will be, first,
to characterize emissions  from relatively uncontrolled
domestic pilot plants and foreign full-scale facilities,
and later, to extend the research  to well-controlled
domestic full-scale   plants.    This  second  phase will
indicate how  well controls  can be expected to reduce
the impacts of pollutants of a future synfuels industry.

     Major planned research products associated with
this issue are:

•    A  preliminary  environmental  risk  analysis  for
synfuels and  shale oil production will be made available
in 1983.
•    A report on comparative combustion  technology,
cooling tower emissions and hazardous  VOCs  will  be
produced in 1984.

Issue:  What are the health and environmental risks of
synfuel-related pollutants?

      Regulatory  and enforcement  decisions  rely  on
accurate analysis of  risks to  health and  environment.
EPA  integrates  exposure and  effects assessments of
synfuel pollutants into risk analyses  which can be used
to evaluate potential health and environmental impacts
of  the   pollutants.    The   assessments   consider
meteorological,   hydrological,   demographic    and
environmental characteristics specific to the  location
of synfuel facilities.
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                       Energy
      EPA's research will also produce technology-based
risk analyses for coal gasification, direct and indirect
liquefaction technologies,  and oil shale.  The research
will  also  provide risk  analyses  for  other  synfuel
technologies in  support  of the permit process and  the
Synthetic Fuels  Corporation.  The information from  the
research can be used to examine  such questions as: Will
hazards  be reduced if the  plant is  sited elsewhere?
What are  the cost/benefit considerations for locating
the   plant  at  different   sites?     What  levels   of
environmental control are appropriate for the area in
which the facility is  to  be  located?  What are  the
hazards associated with  not having additional controls?
What  reduction  of  hazard  occurs  with  additional
controls?

      The  research method  in risk  assessment uses a
risk analysis unit  (RAU) approach in which chemicals
are grouped into classes based upon their occurrence in
waste streams  and   their  biological,  physical   and
chemical characteristics.   Chemicals identified  from
the data collected by EPA  will be placed in RAUs, each
of which will then be analyzed to determine the health
and  environmental risks  of  the entire  RAU.    The
research  program will  determine   which RAUs   are
insignificant and  need minimal  attention, and  which
RAUs constitute a potential hazard and therefore must
be more intensively studied.

      Research  will  focus on   RAUs,  upgrading   the
documentation of  the impacts for critical  classes  of
synfuel  pollutants, refining the  data about exposure
pathways within atmospheric, aquatic and  terrestrial
media; and providing  dose/response data for health  and
environmental effects. Major research areas include:

•     Continued  development  of  models for predicting
the transport and  transformation of  synfuel pollutants
in  the  atmosphere,  and  in aquatic and  terrestrial
systems.
•     Evaluation of the impact of synfuel pollutants on
terrestrial and aquatic food chains with emphasis on  the
uptake of  synfuel  chemicals  and their by-products by
food chains leading to humans.
•     Documentation   of   the importance  of  major
organic  air  and  water  pollutant  RAUs  to provide
estimates of ground-level concentrations.
•     Documentation  of   human  health   impacts   for
synfuel pollutants  as determined  from occupational and
ambient exposures.
•     Evaluation  of exposure  and  human effects  to
develop dose/response functions  for  carcinogenic  and
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reproductive risk analysis under ambient environmental
conditions and within the workplace.

Major  research milestones associated  with  this  issue
are:

•    Initial health effects risk analyses for indirect and
direct  liquefaction  and shale  oil production  will  be
provided in 1983.
•    A report  on exposure-health relationships in coke
oven  workers  — a  surrogate  for  coal-based synfuel
technologies — will  be made available in 1984.  This
work  re-evaluates  some  of  the  earlier  studies  by
employing new data and updating those studies.
•    A report on the uptake of  synfuel  pollutants by
vegetation will be produced in 1984.
•    An environmental risk analysis update for indirect
and direct  liquefaction technologies will be produced in
1984.
•    A summary report  on  aquatic  exposure/toxicity
data,    wildlife    toxicology    and    atmospheric
transformation  rates  and  products   for  major  Risk
Analysis Units will be produced in 1985.

Issue:  What are the reliability and effectiveness of
synfuel pollutant emissions reduction technologies?

      Each  synfuel  production  process  has  its  own
pollution output, which may be  discharged to air, water
or land.  Different pollutants require different degrees
of control and there are numerous control  options to
choose  from.  Before  deciding on a  set  of emissions
reduction technologies at a  plant, a detailed comparison
of  control  alternatives  will help  to  meet emissions
limits at the least cost.

      EPA's research program stresses the evaluation of
existing  synfuel pollutant  reduction  technologies for
performance, reliability and  cost trade-offs.  A minor
effort will investigate  a  novel  technique for difficult,
high-cost clean-up problems.  Data will continue to be
collected from pilot-scale plants.  When a commercial-
scale plant comes on line, it will serve as the validation
mechanism for the earlier data.

      Other  EPA-sponsored  research  will  test  new
methods for removal/recovery  of  sulfur species (COS,
H-S, CSj) from synfuel gas streams.   For example, the
Claus/Scott and Stretford processes on high-CO2 gases,
plus key solvent evaluation for acid-gas cleanup, will be
investigated.    Wastewater  treatability  studies  are
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                       Energy
focused  on  post-biological  treatment.     Emissions
reduction technology  and  characterization  data  are
being used  to complete a set  of  pollution  control
technical manuals  for  specific  commercial  synfuel
processes.   The  data is also  being  used to  provide
environmental  engineering  support to  the regions  and
states on environmental  impact statements and permit
reviews.

      A major planned research  product associated with
this  issue is publication of a major  report  on sulfur
clean-up  technology  and   wastewater treatability in
1984.

Issue: What is the best approach to monitoring synfuel-
related  pollutants?

      Synfuel products and  processes may pose greater
health and environmental  risks than  those associated
with  traditional   petroleum   and  coal  combustion
facilities.    Development  of  the  synfuels  industry
requires the  assurance that  the  industry  poses  no
unacceptable  risks to human health,  welfare or  the
environment.   Such assurance depends on factual data
that pollution from synfuels facilities are not reaching
unacceptable  levels.    Monitoring will  provide  this
factual  data.

      The environmental monitoring issue is specifically
identified in the  Energy Security Act of  1980.   All
applicants  who  plan to   build  synfuel  plants with
financial   assistance    from   the   Synthetic  Fuel
Corporation (SFC) must provide SFC with an acceptable
outline  of an environmental monitoring plan.  EPA, in
conjunction with   DOE,  will   produce  the  reference
information  that  applicants  can  use   to   develop
monitoring plans and that the SFC Board of Directors
can use in their review of the plans.

      Another  major  function  of   EPA's  synfuels
research program  is to provide technical  assistance to
states and EPA regions for  monitoring proposed synfuel
plants.    The  assistance   will help  to  ensure  that
monitoring plans adopted by the states are technically
adequate and  able to meet requirements set forth in
permits.

      EPA's synfuels monitoring research will  analyze
the  applicability  and cost effectiveness of  existing
monitoring  technologies in terms  of  their  use in
tracking the expected synfuel pollutants.  The research
will  identify the species to monitor, and  the sites  and
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frequencies of sampling.  It will also provide guidance
for identifying new  species which  may not have been
present in measurable amounts in pilot-plant emissions.

     Results from this research will be published in a
single,  integrated   manual  that  will  describe  the
monitoring to be carried out and the procedures to use.
This manual,  to be published in 1983, will represent the
state  of  the  art  for  monitoring  with   existing
technologies.   After  this  manual is  published,  the
research program addressing the  synfuels monitoring
issue  will be reduced  until  experience  with  the
operational plants  indicates that  further research  is
necessary.

Issue:  How do boiler conditions influence key
pollutant-related physical and chemical reactions?

     Complex and  subtle   physical  and   chemical
reactions take place in the combustion zone of  coal-
fired boilers.  Boiler manufacturers and operators have
studied these reactions extensively  to make  boilers
more efficient; the  reactions are now being studied to
optimize NO  and  SO   control.   For  example, lower
boiler flame temperature reduces the formation of NO
emissions.  A fuller understanding of the reactions that
occur in the  combustion zone will  enable  scientists to
understand the  cause-and-effect  relationships  which
then can be used to develop engineering design data.

     EPA  scientists and engineers are  addressing  a
number  of  questions   about  the  fundamentals  of
combustion.  For example, as the amount  of oxygen  is
varied in the zone, how do  NOx emissions  vary?  At
what portion of the flame front does oxygen injection
produce the least amount of NO ?  What compounds are
created in  different flame zones?  Are the compounds
destroyed  as  they pass from primary to secondary to
tertiary flame zones?  If SO  and  NO  compounds are
destroyed in some portion of the flame can they be kept
from re-forming? How does the percentage of sulfur  in
coal affect the compounds that are formed and the rate
of  formation?   What  is the  trade-off between SO
control and NO  control within the same boiler?  What
temperature  gradients are optimum for SO  and NO
control?

     Specific studies  will determine the mechanisms
and rates  associated with the  volatilization of sulfur
species from the coal particle matrix.  The studies will
also identify  the role of fuel-bound nitrogen  and  its
evolution  from  the  coal  particle   matrix   in  the
                        126

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                       Energy
formation of NO  .  (Much of the NO  from combustion
processes is a result  of fuel-bound nitrogen.)  A  more
thorough determination of the role of the fuel nitrogen
in NO  production is expected by early  1984.  The rates
and mechanisms associated with volatilization of sulfur
species from coal will be determined by  1985.

     Once  the   fundamental  reactions  indicated  by
laboratory experimentation  are duplicated at prototype
scale,  the results of  the  experiments will be used to
develop engineering designs. Results from this research
will  support  engineering and design  evaluations  being
done by industry and by EPA.

     A major planned research product associated with
this  issue is  a complete performance  optimization of
industrial boiler low-NO  burner evaluation in  1983.

Issue:  What configurations employing LIMB/low-NOx
burners promise reduced emissions control costs?

     Limestone  injection   multi-stage   burner (LIMB)
technology is  an  evolving concept  for  controlling SO
emissions  from   boilers.     Limestone  injected  at
appropriate  places in a  boiler  combustion  zone can
chemically  capture  sulfur  compounds, keeping  them
from  being emitted  as  air pollution.   When used in
tandem with low-NO   burners or staged combustion to
control NO  emissions, a  LIMB/low NO  system is a
potentially  attractive alternative   to  current   wet
scrubbers, now in widespread use. The LIMB technology
could  cut construction costs by as  much as 75% as
compared with wet scrubbing technology.  In addition,
LIMB systems produce a dry waste which may be  more
easily  disposed of than wet scrubber  sludge.   LIMB
technology  is also appropriate  for  retrofit  to  some
existing  boilers.  While LIMB is  not expected to  be as
effective as the wet process in removing SO  , it  could
prove to be an invaluable part of an overall system for
SO /NO  control.   Ultimately, the benefits from  a
LIraB  system  will be a dry, less expensive, efficient
SO /NO  integrated pollutant  removal  system applied
to utility or industrial boilers.

     The key to  achieving  a commercially acceptable
LIMB  system  is  to have  one  (or  more)  host  boiler
operators install  and operate such a  system  under
realistic conditions.   But  such a host may hesitate to
make  the  capital investment  in LIMB until  there  is
convincing  engineering  data   to   suggest   that  the
investment is  sound.  Developing that engineering data
is the  goal  of EPA's  LIMB research program.   It  is
expected that such data will be available by 1986.
                        127

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                       Energy
      The LIMB research program is proceeding along a
number of  paths.   Fundamental  chemical  reactions
described earlier will be used as a basis to design pilot-
and bench-scale LIMB systems for pulverized coal wall-
fired  and  tangentially-fired boilers.    Concurrently,
scale-up  engineering  parameters  for  utility-scale
boilers  will be developed and cost-effectiveness  data
evaluated.   The objective is  to produce the  scientific
data  and  engineering  parameters  that will  enable
commercial boiler  manufacturers to design,  build and
eventually   to  produce  LIMB  systems  with  private
capital.  Another research effort involves  a systems
evaluation  of how  LIMB  can be integrated with other
control  technologies   such  as  coal  cleaning,  dry
scrubbers, and particulate controls to achieve necessary
emissions reductions at the lowest overall cost.

      Once   the   research   provides  the   necessary
fundamental information  so that commercial  LIMB
adaptation,  scale-ups,  and  design  can take place, the
next  phase  of  research is to take  performance  data
from  a host  operator.    Integral  to  this  effort   is
continuing   information  exchange  and   cooperation
between EPA and manufacturers and  utilities interested
in  the  progress  and  potential  of  LIMB/low-NO
emissions reduction technology.

      A major planned research  product associated with
this issue is the production of a system analysis study of
the LIMB process to be available in 1983.
                         128

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      Chapter Eight
EXPLORATORY RESEARCH

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EXPLORATORY RESEARCH
Outline:
Introduction
Legislative Mandate
Background
Major Research Issues
     Issue:    What  are  the  best  indicators  of an
     environmental impact?
     Issue:  What factors control biodegradability?
     Issue:  What are the most accurate measurement
     processes for airborne pollutants?
     Issue:  How do pollutants interact with soils?
     Issue:  What happens to pollutants at  the  water-
     to-air interface?
     Issue:    Can  water  treatment  be made  more
     efficient through a  better understanding of unit
     processes?
                        130

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                Exploratory Research
INTRODUCTION

     Many  of  today's  environmental problems  might
have been avoided if in the past  there  had been  a
clearer   scientific   understanding   of   the  physical,
chemical  and   biological  relationships  among  the
environment, pollution and man.  EPA is focusing much
of its research  on solving the problems,  mitigating the
hazards of  immediate concern  and providing a  sound
basis  for  regulations  as described  in  the preceding
chapters  of  this  Research Outlook.    Within  that
research framework, there is  limited room  for seeking
entirely  new  knowledge and fundamental  scientific
information. It  is, however, just such information that
will  yield  major  advances  in  controlling today's
environmental  problems, and provide the  means for
mitigating future problems.  EPA's exploratory research
program is  the vehicle  by which  EPA broadens  and
deepens its base of scientific knowledge.

BACKGROUND

     The primary  goal  of  the exploratory research
program is to develop new knowledge and principles for
defining  and   predicting  the  relationships  between
physical and chemical factors and biological systems.
A secondary goal is to  identify  emerging problems or
ways to handle current problems more effectively.  The
mechanisms used to  pursue these goals are research
grants.    Research grants  are  based on  competitive
proposals   from  scientists  qualified  to  investigate
specific facets of the environment.

     University research centers     operate    under
cooperative  agreements   with   EPA   to   conduct
multimedia/interdisciplinary  research   focused   on
specific environmental problems.  Each center extends
the capabilities  of EPA laboratories in specific research
areas —  filling research gaps,  providing broad-based
scientific   advice   and  serving  as   a   source  of
professionals with an  expertise which is valuable to the
agency.   The current centers  and their  inauguration
dates are:

      1979:
     Epidemiology—University of Pittsburgh
      Advanced  Environmental   Control  Technology-
     University of Illinois at Urbana
     Ground  Water—Consortium  of   University  of
     Oklahoma, Oklahoma  State  University,   Rice
      University
                           131

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                Exploratory Research
     1980:
     Industrial  Waste  Elimination—Consortium   of
     Illinois  Institute of  Technology,   University  of
     Notre Dame
     Intermedia  Transport—University   of  California,
     Los Angeles
     Ecosystems—Cornell University
     Marine Sciences—University of Rhode Island
     1981:
     Hazardous Waste—Louisiana State University

LEGISLATIVE MANDATE

     In all proposed  authorizations  for  EPA research
and development funds for each fiscal year since fiscal
year 1978, Congress has  designated a portion of these
funds to support what has been variously termed long-
term, anticipatory,  or basic research and development.
Of these bills, four have been enacted:  1978—P.L. 95-
155, 1979—P.L.  95-^77, 1980—P.L. 96-229, and 1981—
P.L. 96-569.

MAJOR RESEARCH ISSUES

     The  items that follow  by no means  cover the vast
range  of   topics  of   interest  to  EPA's exploratory
research program.  They are, rather, topics that have
been described in the 1983 solicitation for research.

Issue:  What characteristics best indicate  an environ-
mental impact?

     Often descriptors of an environmental impact on
an ecosystem only  indirectly relate to the vitality of
the affected system.  Most impact descriptors now in
use  are physical  parameters  and  concentrations  of
substances known  to  affect the  environment to some
degree.  That ecosystems do respond to certain mixes
and/or  levels of these characteristics  is known, but
research is needed to determine how systems respond to
perturbations  and  to describe  system   stability  and
resilience. In short, what are the characteristics of an
ecosystem response?

     EPA's exploratory research will survey the data
that have been  produced  to  describe  environmental
stress   factors.     Ecosystem  mixes   for  healthy
environments  will  be identified  and compared  with
ecosystems  that  have  undergone  species  diversity
changes due to pollution.  The  comparison will help to
identify  system  variances  and  the   spectrum  of
responses.
                         132

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                Exploratory Research
      Some  significant problems  are expected  to be
encountered in this  research.   For  example,  some
ecosystem processes operate over long periods and may
not reveal responses for some time; a method is needed
to identify  those  responses.  Additionally, ecosystems
vary  based  on  location, which makes similar  pollution
inputs significant in some areas but  of small concern in
others; techniques are needed to differentiate responses
by region and other sample parameters.

      Once  the nature of ecosystem stress  is described
in detail,  investigators  may proceed  to determine
damage   on   the   sub-cellular,   physiological   and
behavioral  levels.   This, in  turn,  could improve the
capacity for identifying sub-lethal stresses and cause-
and-effect  relationships.  Such a  capability could be
used  to  detect  problems  before  individual  deaths,
population reductions or species extinction.

      The long-term objectives of  the research are to
determine which pollutants can or cannot be handled by
defined  biological  systems, what  level of control of
pollutants is required to minimize damage and how best
to achieve  control.    A current  thrust in  the   EPA
research  grants  program   focuses on methods to
determine  impacts   on   organisms  comprising  the
environmental biota in specific locales and  to integrate
these techniques into a holistic predictive methodology.

Issue:  What are the fundamental factors  that control
the biodegradability of substances?

      Ecosystems have the natural  ability  to recover
from  exposure to  many types and  concentrations of
pollutants.   One  of  the  major  mechanisms through
which  ecosystems   neutralize  toxic   substances  is
microbial degradation.  Although much is known about
biodegradation,  the  basic  factors  are   not   fully
understood.      Moreover,   whether  pollutants   are
biologically  degraded or whether the intermediate by-
products of  a pollutant's biodegradation are innocuous
could be crucial information for a scientifically correct
pollution control decision.

      EPA's   exploratory  research   program  seeks to
develop  an   understanding  of fundamental  scientific
factors (such as the identity and characteristics of the
dominant degrading organisms, the  factors influencing
the rate of  biodegradation  and their specific modes of
action) involved in  biodegradation.   The objective of
                        133

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                Exploratory Research
this  research  is to relate  a chemical's characteristics
with   an   organism's   degradation   capabilities  to
determine  whether  specific  chemical  inputs to  an
ecosystem containing the organisms will cause damage.

     Information resulting from this  research  will also
help improve waste and wastewater treatment, protect
water  quality  and  drinking  water  resources, assist
industry  to assure that process waste  streams minimize
problems, and develop regulatory  monitoring protocols
and  test procedures  for   determining  water  quality
integrity.

     Current   research  includes  studies  to  upgrade
anaerobic  treatment   of   industrial  and  municipal
wastewater,  to  increase   process reliability  and  to
realize the energy potential of the methane  gas that is
generated.

Issue:  What measurement processes can more accurately
detect fine particles and airborne pollutants?

     Scientists need precise data to learn more about
the nature and effects of pollutants found  in the air.
This is especially true for new or exotic air pollutants
often  found  in  low,  but  nonetheless   significant,
concentrations,  and for carbonaceous  particles whose
importance as agents for promoting chemical reactions
and  whose potential role as agents for emission control
have recently become apparent.   EPA's research will
produce  fundamental chemical and physical knowledge
to assist the  development of precise instruments to
measure low concentrations.  In-situ methods may solve
the  artifact  problems.   Promising  technologies  for
detecting low concentrations are active remote sensing,
such   as  infrared  and  laser  optical  devices,  and
techniques to  analyze wave-front  interference patterns
to detect compounds.  The research  will be useful  for
developing  a  better  understanding of  atmospheric
chemistry  and  a more accurate description of the
kinetics  involved.  Ultimately, the research will  make
air pollution transformation models more  scientifically
rigorous and, therefore, more  useful to EPA.

Issue:  How do pollutants travel through, and react with,
soils?

      To determine  how pollutants affect underground
sources  of  water, it  is necessary to understand the
mechanisms of movement through, and the  interaction
of  pollutants  with, the subsurface  environment. This
subsurface  environment plays a dominant role in the

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                Exploratory Research
transport and fate of contaminants.  The aim of EPA's
exploratory  research  in  this  area  is  to  develop
information   sufficient   to   predict   ground-water
contamination from both existing and future polluting
sources.  EPA's research in this area is coordinated with
the U.S. Geological Survey (USGS).  USGS research is
directed  primarily  toward determining  the locations,
quality  and  amounts  of  ground  water,  including
assessing the impacts of contamination on water quality
and  quantity.    EPA research  is  directed  toward
understanding the processes that influence contaminant
behavior in the  subsurface with the goal of predicting
the  impact  of  contamination on underground  water
sources.  Current research is characterizing subsurface
parameters   that    influence   the    ground-water
contamination  processes,  processes  that control the
mobility  and transformation of  pollutants,  including
microbial activity.  New techniques to detect and trace
subsurface pollution plumes are needed  to assure that
data  collected  are  of high  quality.    The  sorption
characteristics of various classes of organics of concern
in    ground-water     contamination    are    being
mathematically  described for inclusion in ground-water
models.

Issue: What are  the fundamental dynamics of the water-
to-air interface that relate to pollutants?

     Pollution moves  between the three environmental
media — air, water and land.  The rates and nature of
that movement  are controlled by complex, and  as yet
unclear, chemical, physical and biochemical processes.
But  environmental   protection  regulations  and  the
scientific  data to support them tend to concentrate on
a  single  phase  of  the media,  which  can  result  in
overlooking the  contributions of other phases.   EPA's
exploratory  research  into the water-to-air  interface
centers on investigating the basic scientific aspects of
intermedia transport and transformation. The research
focuses  on physical and chemical phenomena, such as
solubility and diffusivity, which are known to influence
transfer at the interface, and on the roles of suspended
sediment and turbulence in the transfer.  The resulting
information  will   be  used  in   models  to   predict
concentrations of toxic pollutants in air and water and
their  variation  with  other  atmospheric  and aquatic
factors.
                        135

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                Exploratory Research
Issue: How can water treatment methods be improved
through a better understanding of unit processes?

     Current  water  treatment techniques and water
pollution     control     methods     use     specific
physical/chemical/biological  reactions, known  as  unit
processes,  as  their  primary  means  of  operation.
However, many fundamental mechanisms that influence
the  performance  of unit  processes are   not   well
understood.  This  lack of  knowledge has  prevented
engineers  from  designing  the  most  cost-effective
control  systems.   To help fill this information  gap,
exploratory  research in water  treatment will focus on
determining the role of bioflocculation and  biofilm in
wastewater  treatment processes and receiving  waters,
identifying and measuring the influence of particulates
on  process  effectiveness,  determining  the reaction
kinetics, products and reaction mechanisms of oxidants
and   other   alternative   disinfectants,   describing
dislodging mechanisms during  filter backwashing and
understanding the bioactivity of activated sludges.  One
of the EPA exploratory research projects in this area is
currently investigating  a  novel  approach   to  water
treatment to  create polymerization of  compounds so
that they become insoluble and settle out more rapidly
and  at  lower temperatures.   This process  would be
useful to industries in cold climates that have to store
wastes  in large holding tanks  during  the winter until
warmer weather enables the use of biological treatment
processes.  Other research is looking at ways  to reduce
the  volume of sludge and put  it in a more treatable
form by  de-watering it  with  new moisture-removal
methodologies.   The research  is  balanced  between
gaining  a basic understanding of the unit  processes and
applying that  understanding  to  specific  current and
expected water pollution control situations. The results
of the program should produce information upon which
to   base  future   designs  of  cost-effective  water
treatment control technology.
                        136

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 APPENDIX A:



Resource Options

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APPENDIX A

RESOURCE OPTIONS

     The law  requiring the submission of this research
strategy document to  Congress is Section 5 of Public
Law 94-475.  The same law also requires that  a  five-
year projection be  provided  indicating  the  potential
research response to different  resource levels.

     The  following  section  on  resource   options
includes,  as  required  by  the  law,  descriptions  of
conditions  for high,  moderate  and no  growth.   The
growth  rates associated with these options are zero for
no growth, three percent for  moderate growth  and six
percent for high growth.  No additional  resources are
required or expected  as a result  of  this submission.
Rather,  these  growth   scenarios  are  intended,  as
required by the law, to  indicate  potential program
increases in EPA's research and development.


HAZARDOUS  WASTE


     1983 CURRENT ESTIMATE $33.0 MILLION*
GROWTH

None
Moderate
High
PROJECTIONS
198*
27.4
27.4
27.4
1985
27.4
28.2
29.0
1986
27.4
29.1
30.8
1987
27.4
29.9
32.6
              Figures are in millions of dollars

     No Growth:    The   program  will  proceed  as
described in this Research Outlook.
     Moderate Growth:  Additional efforts will seek to
discover the key factors leading to the failure of soil,
clay or  synthetic liners   for hazardous waste land
disposal sites.
     High Growth:  Techniques to detect and monitor
subsurface movement of hazardous waste leachate will
be further investigated. Emphasis will be on identifying
key early indicators of leachate migration problems.

     *The 1983 number includes $2.4 million which was
used  for exploratory research  grants  and  centers.
These funds will be included directly in the exploratory
research budget in 1984 and, therefore, are not included
in these projections.
                         139

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WATER QUALITY
      1983 CURRENT ESTIMATE $30.6 MILLION*
GROWTH     PROJECTIONS
              1984      1985     19S6      1987
None         19.2      19.2      19.2      19.2
Moderate     19.2      19.8      20.4      21.0
High          19.2      20.4      21.6      22.9
              Figures are in millions of dollars

      No Growth:    The  program  will  proceed  as
described in this Research Outlook.
      Moderate Growth:   Efforts to  develop flexible
protocols for determining  site-specific water  quality
will  be  accelerated  as  will  efforts to  transfer such
capabilities to state and local environmental officials.
      High Growth:   Efforts  will be  accelerated to
develop regimens for characterizing the ecosystems of
potential   ocean   outfalls   and    dumping   sites.
Investigations  of   early   indicators   of  potentially
negative ecosystem  responses will also be accelerated.
These activities are in addition  to  those listed above
under moderate growth.

      *The 1983 number  includes $1.1 million which was
used  for  exploratory research   grants  and  centers.
These funds will  be incorporated  in  the  exploratory
research budget in 1984 and, therefore, are not included
in these projections.
                       140

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DRINKING WATER
      1983 CURRENT ESTIMATE $23.3 MILLION*
GROWTH     PROJECTIONS
              1984      1983     1986      1987
None         20.9      20.9      20.9      20.9
Moderate     20.9      21.5      22.2      22.8
High          20.9      22.2      23.5      24.9
              Figures are in millions of dollars

      No Growth:    The  program  will  proceed  as
described in this Research Outlook.
      Moderate Growth:    Additional  efforts  will  be
initiated  to  determine  with  greater  precision  the
potential health  effects of those substances that are
found in drinking water treated  via various disinfection
processes.  Focus will  be on those contaminants that
are  non-volatile  and,  therefore,  have  yet  to  be
investigated in any great detail.
      High Growth:  The additional efforts cited under
the moderate growth option above will be augmented
and accelerated.

      *The 1983 number includes $1.9 million which was
used  for exploratory  research grants  and  centers.
These resources will be incorporated in the exploratory
research budget in 1984 and, therefore, are not included
in these projections.
                        Ill

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TOXIC SUBSTANCES AND PESTICIDES
      1983 CURRENT ESTIMATE $33.7 MILLION*
GROWTH     PROJECTIONS
              1984     1985     1986     1987
None         29.8     29.8      29.8      29.8
Moderate     29.8     30.6      31.6      32.6
High          29.8     31.6      33.5      35.5
              Figures are in millions of dollars

     No Growth:    The   program  will   proceed  as
described in this Research Outlook.
     Moderate Growth:      Investigations  into   the
relationships between  a chemical's structure  and its
chemical, physical and  biological properties  will  be
accelerated.
     High Growth: Additional efforts will be made to
link  health and ecological  effects with various models
that describe the steps in the life cycle of a substance
from its production  and  release  to   its  ultimate
destination.    Such efforts  are  in  addition to  those
mentioned under moderate  growth above.

      *The 1983 number includes $1.5 million which was
used  for exploratory research  grants   and  centers.
These resources will be incorporated in the exploratory
research budget in 1984 and, therefore, are not included
in these projections.

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AIR
      1983 CURRENT ESTIMATE $59.4 MILLION*
GROWTH     PROJECTIONS
              198*     1985     1986     1987
None         51.2     51.2      51.2      51.2
Moderate     51.2     52.7      54.3      55.9
High          51.2     54.3      57.5      61.0
              Figures are in millions of dollars

     No Growth:    The   program  will   proceed  as
described in this Research Outlook.
     Moderate Growth:  Additional  work will improve
the technology and techniques  available  for measuring
and monitoring hazardous air  pollutants.
     High Growth:  An increased effort  will identify
more clearly  the causes  and  mechanisms of  human
responses to air pollutant exposures.  This effort  will be
in addition to that cited under moderate growth above.

      *The 1983 number includes $4.7 million which was
used  for exploratory  research  grants  and  centers.
These resources will  be incorporated in the exploratory
research budget in 1984 and, therefore, are not included
in these projections.

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ACIDIC DEPOSITION
      1983 CURRENT ESTIMATE $12.5 MILLION
GROWTH     PROJECTIONS
              1984     1985     1986     1987
None         14.0     14.0      14.0     14.0
Moderate     14.0     14.4      14.9     15.3
High          14.0     14.8      15.7     16.7
              Figures are in millions of dollars

     No Growth:    The   program  will  proceed  as
described in this Research Outlook.
     Moderate Growth:      In   the    source-receptor
relationship area, additional efforts  will  be  made to
improve  methods  for  identifying  the  source of  a
particle by its "fingerprints." Work with tracers will be
accelerated.
     High Growth: Efforts to delineate between actual
acidic  deposition trends and other cyclic meteorologic
influences will be advanced  and the efforts described
under moderate growth above will  be accelerated.

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ENERGY
      1983 CURRENT ESTIMATE $12.5 MILLION*
GROWTH     PROJECTIONS
              198*     1925     1986     1987
None          9.5       9.5      9.5       9.5
Moderate      9.5       9.8      10.1      10.4
High           9.5      10.1      10.7      11.3
              Figures are in millions of dollars

     No Growth:    The   program  will   proceed  as
described in this Research Outlook.
     Moderate Growth:     Efforts   to   characterize
reaction  conditions  in limestone-injected  multistage
burner  configurations  will  be  accelerated.    The
information  produced   will   serve   to   guide   the
development of more refined (more effective) emissions
reduction configurations.
     High Growth:     The   efforts   described  under
moderate  growth  above  will  be  augmented  and
accelerated.

     *The 1983 number includes $1.4 million which was
used  for exploratory  research  grants  and  centers.
These  funds will be  incorporated  in  the exploratory
research budget in 1984 and, therefore, are not included
in these projections.

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EXPLORATORY RESEARCH
      1983 CURRENT ESTIMATE $17.5 MILLION*
GROWTH     PROJECTIONS
              1984     1985     19S6     1987
None         15.5      15.5      15.5      15.5
Moderate     15.5      16.0      16.
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   APPENDIX B:



Technical Reviewers

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                                APPENDIX B

                             Technical Reviewers
The entire Research Outlook 1983 was reviewed by the following
Science Advisory (SAB) Members:
SAB Subcommitte on the Research Outlook:

     Dr. John Neuhold, SAB Subcommittee Chairman, Utah State
                      University
     Dr. Edward F. Ferrand, New York City Department of
                           Environmental Protection
     Dr. N. Robert Frank, Georgetown University
     Dr. Leonard Greenfield, Private Consultant
     Dr. Morton Lippmann, New York University
     Dr. Francis C. McMichael, Carnegie-Mellon University
     Dr. Daniel Menzel, Duke University
     Dr. Anne M. Wolven, A.M. Wolven, Incorporated
SAB Executive Committe:

     Dr. Earnest F. Gloyna, SAB Committee Chairman, University
                           of Texas
     Dr. Herman E. Collier, Jr., Moravian College
     Dr. Sheldon K. Friedlander, University of California
     Dr. Bernard Goldstein, Rutgers Medical School
     Dr. Daniel Harlow, Diamond Shamrock Corporation
     Dr. Rolf Hartung, University of Michigan
     Dr. Julius E. Johnson, Private  Consultant
     Dr. Roger O. McClellan, Lovelace Biomedical and
                            Environmental Research Institute
     Dr. Robert Neal, Chemical Industry Institute of Toxicology
     Dr. John M. Neuhold, Utah State University
     Dr. Gerard Rohlich, University of Texas
EPA Editorial/Production:

     Richard M. Laska, Office of Research and Development
     Katherine S. Weldon, Technical Information Office
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Individual Chapter Reviewers:

Hazardous Wastes;

     Dr. Martin Alexander, Cornell University
     Dr. William T. Gulledge, Chemical Manufacturers Association
     Mr. Ernest C. Ladd, FMC, Incorported
     Dr. Dames O'Rourke, Camp Dresser and McKee, Incorporated
     Dr. Dave Rosenblatt, USA Medical Bioengineering Research
                          and Development Laboratory

Toxic Substances and Pesticides;

     Dr. Kenneth Duke, Battelle Memorial Institute
     Dr. Wendell Kilgore, University of California at Davis
     Dr. George Manring, National Wildlife Federation
     Dr. Robert G. Tardiff, National Academy of Sciences
     Dr. Dewayne Torgeson, Boyce Thompson Institute for Plant Research
     Dr. William Tweedy, Ciba-Geigy

Water Quality;

     Dr. C. Fred Gurnham, Peter  F. Loftus Corporation
     Dr. Albert H. Lasday, Texaco, Incorporated
     Dr. Perry McCarty, Stanford University
     Dr. Mary McKown, Battelle Memorial Institute

Drinking Water;

     Dr. Jay Lehr, National Water Well Association
     Dr. Edwin Lennette, California Department of Health Services
     Dr. Jack Mannion, American Waterworks Association
     Dr. Nina I. McClelland, National  Sanitation Foundation
     Dr. Abel Wolman, John Hopkins University

Airt

     Dr. Edward J. Burger, Georgetown University Medical Center
     Dr. Frank Gifford, Oak Ridge National Laboratory
     Dr. Stan Greenfield, Systems Applications  Incorporated
     Dr. Lester Machta, National Oceanic and Atmospheric Administration

Acid Deposition;

     Dr. George Hidy, ER&T Corporation
     Dr. Rick Linthurst, North Carolina State University
     Dr. Joseph Street, Utah State University
     Dr. Glen Hilst, Electric Power Research Institute
     Dr. Robert Brocksen, Electric  Power Research Institute
                               150

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Energy;
      Dr. Marvin Drabkin, U.S. Synthetic Fuels
                         Corporation
      Dr. L. Barry Goss, Battelle Memorial Institute
      Dr. Dennis Meadows, Dartmouth College
      Dr. Laszlo Pasztor, Dravo Corporation
      Dr. Gordon Newell, Electric Power Research
                         Institute
      Dr. Ron Wyzga, Electric Power Research
                     Institute
Exploratory Research;

     Dr. Herbert Allen, Illinois Institute of Technology
     Dr. Bernard B. Berger, University of  Massachusetts
     Dr. Brue Hicks, National Oceanic and Atmospheric
                     Administration
     Dr. James Kramer, McMaster University
     Dr. Steven Stryker, Battelle Memorial Institute
Chapter Principals,
EPA Office of Research and Development:

Hazardous Wastes: Matt Bills

Toxic Substances and Pesticides: Frode Ulvedal

Water Quality:  Jim Basilico, Jay Benforado, Tom Pheiffer
                Herb Quinn,

Drinking Water:  Marv Rogul

Air: Chuck Brunot, Bill Keith

Acid Deposition: Gary Foley

Energy: Al Galli, Dave Graham

Exploratory Research: Don Cook, John Reuss
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