EPA/600/9-90/033
                        September 1990
           FY-1991
       EPA Research
       Program Guide

   October 1, 1990 - September 30, 1991
Office of Research and Development
U.S. Environmental Protection Agency
      Washington, DC 20460

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Notice
The program descriptions and resource estimates included in this
document reflect the latest detailed information available at time of
publication. Time will change some of this information. In addition, the
resource figures have been rounded off and some smaller programs
omitted. For the latest information, you may want to contact the
individual listed.

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Contents
Introduction  	  1

How to Use the Program Guide 	  2
Air 	  3
 Hazardous Air Pollutant Regulatory Activities  	  3
 Mobile Source Pollutant Regulatory Activities  	  8
 Mobile Sources  	  10
 National Ambient Air Quality Standards (NAAQS)   	   11
 New Source Performance Standards and State
  Implementation Plans 	  15
 Indoor Air Pollution Activities  	  18
 Global Change Research 	  20
 Global Climate Change 	  23
 Health Effects Institute  	  23
Drinking Water  	  25
 Health Effects of Drinking Water Contaminants  	   25
 Ground Water Research 	  26
 Ground Water  	  26
 Drinking Water Technology  	  27
Water Quality  	  30
 Water Quality Based Approach/Permitting  	   30
 Industrial Wastewater Treatment Technology  	   31
 Wastewater Treatment Technology 	   32
 Marine, Estuaries, and Lakes 	  34
Hazardous Waste 	  37
 Alternate Technologies	  37
 Incineration 	  37
 Land Disposal  	  39
 Pollution Prevention  	  39
 Municipal Solid Waste 	  40
 Municipal Solid Waste Monitoring  	   41
 Quality Assurance  	  43
 Releases  	  43
 Waste Characterization  	  45
 Waste Identification   	  47
Toxic Substances  	  49
 Biotechnology  	  49
 Biotechnology/Microbial and Biochemical Pest Control
  Agents  	  50
 Ecology: Ecotoxicity and Risk Assessment  	   52
 Ecology: Transport/Fate/Field Validation  	   53
 Exposure Monitoring  	  53
 Health: Markers, Dosimetry, and Extrapolation  	   54
 Special Human Data Needs   	  55
                                111

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Contents (continued)
 Structure Activity Relationships  	  55
 Support for Toxic Substances Control Act (TSCA)  	  56
 Engineering  	  57
 Test Method Development  	  59
 Emergency Planning and Community Right to Know 	  60
 Asbestos  	  60
 SARA Title III  	  61
Pesticides  	  62
 Biotechnology/Microbial and Biochemical Pest
  Control Agents 	  62
 Ecology: Ecotoxicity and Risk Assessment  	  63
 Ecology: Transport/Fate/Field Validation  	  64
 Engineering  	  65
 Exposure	  66
 Health: Markers, Dosimetry and Extrapolation 	  66
 Support  	  67
 Test Method Development  	  67
 Support for Federal Insecticide, Fungicide and
  Rodenticide Act (FIFRA) Activities  	  68
Multimedia—Core 	  69
 National Health and Nutrition Examination Survey
  (NHANES-III) 	  69
 Center for Environmental Epidemiology Research  	  70
 Exploratory Research Grants 	  70
 Research to Improve Health Risk Assessment
  (RIHRA) (Health)  	  71
 Total Human Exposure  	  72
 Ecological Trends 	  73
 Reducing Uncertainty in Ecological Risk Assessment  	  74
 Exploratory Research Centers  	  75
 National Institute of Ecological Research  	  76
Multimedia  	  78
 China Program 	  78
 Task Force on Environmental Cancer and
  Heart and Lung Disease  	  78
 Harvard Study  	  79
 Consistent Risk Assessment 	  79
 Manage ORD's Technology Transfer, Regulatory
  Support and Regional Operations Activities 	  80
 Manage the Mandatory Quality Assurance Program  	  81
 Visiting Scientists Program	  83
 Small Business Innovation Research (SBIR) Program  	  83
 Development, Validation and Standardization of
  Analytical Methods in Support of Regional Programs  	  84
                               IV

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Contents (continued)
Energy  	  86
 Develop and Evaluate LIMB Technology  	  86
 Understanding Atmospheric Processes 	  86
 Establish Deposition Monitoring and Trends  	  87

Radiation  	  88
 Off-Site Monitoring Program   	  88
 Scientific Support for Radon Program 	  88

Superfund  	  90
 Provide Techniques and Procedures for Site and
  Situation Assessment  	  90
 Clean-up of Uncontrolled Hazardous Waste Sites Requires
  Technologies for Response and Remedial Action, for
  Protecting the Personnel Involved and for Supporting
  Enforcement Actions  	  91
 Provide Quality Assurance—Superfund Program
  Requirements  	  92
 Provide Technical Support to Enforcement, Program, and
  Regions  	  92
 Provide Technical Support to Enforcement, Program, and
  Regional Offices  	  94
 Hazardous Substance Health, Risk and Detection 	  94
 Hazardous Substances Health Effects/Risk
  Assessment and Detection Research  	  95
 Superfund Reportable Quantity Regulatory Efforts  	  96
 Innovative/Alternative Technology Research,
  Development, and Demonstration 	  97
 Evaluate Technologies to Manage Uncontrolled
  Waste Sites 	  98
 Manage Hazardous Substance Research Centers
  Program  	  98
 Small Business Innovation Research (SBIR)
  Program—Superfund  	  100
 Superfund Research Grants 	  100
 Field Screening Techniques for Assessment and
  Evaluation  	  101
Overview  	  102

Organization Chart 	  104
ORD Organization  	  105

ORD Organizational Descriptions  	  112
ORD Office/Laboratory Abbreviations  	  127
ORD Key Contacts  	  130

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Contents (continued)
ORD Regional Contacts 	  134
EPA Regional Offices 	  135
                      VI

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Introduction
The free and open exchange of knowledge both stimulates and provides
quality control for the progress of science. This report provides information
on the research which EPA is planning for this fiscal year, on how much
we intend to spend on each program area, and on whom to contact for
further details. More than 60 percent of our research budget will be spent
through extramural contracts, grants, and cooperative agreements with
organizations outside of EPA's laboratories.
   It is our intent to increase the efficiency and effectiveness of this
research by placing great emphasis upon open competition for extramural
support. We hope that the information in this report will stimulate
qualified parties and make their capabilities known to our research
managers so that we all might gain from sharing experience and expertise.
Please feel free to contact any of the parties listed in this report.

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How to Use the Program Guide
The following descriptions of ORD's research program are organized first
by media such as air, water, hazardous wastes, etc. These categories are
further broken down into research foci such as scientific assessment,
monitoring and quality assurance, health effects, environmental
processes, and engineering technology. Each description is a very broad
summary of the research being done, where that research is being done,
who to contact for more information about the program, and both the
approximate total funding for that area and the percentage of total
funding which is reserved by EPA for in-house research.  Funding which is
not reserved for in-house research is spent through extramural contracts,
grants and cooperative agreements.
   For each program description, one or more contacts are listed along
with the major research areas to be pursued. For further  information, you
may call the contacts. Their commercial and Federal (FTS) telephone
numbers are listed in a separate section near the end of this report. Where
two or more research laboratories are listed, please turn  to the "EPA R&D
Organization" section of this report for descriptions of the major mission
and functions of each.
   Some of the research funded for this fiscal year will be done in-house by
EPA's laboratories. The rest will be accomplished extramurally. Proposals
for funds for research in areas of interest to the agency are welcomed and
are considered on a competitive basis. To receive information regarding
application procedures for extramural funds, please contact the person
indicated in the area of specific interest to you. In addition, approximately
fifteen percent of EPA's research budget is used to support long-term
exploratory research. Information regarding funds for exploratory
research grants can be obtained from the:

Research Grants Program
Office of Exploratory Research (RD-675)
USEPA
Washington, DC 20460
(202) 382-5750

   Finally, for further information regarding Office of Research and
Development research publications (600/series) or for additional copies of
this report, please contact:

Center for Environmental Research Information
USEPA
26 W. Martin Luther King Drive
Cincinnati, OH 45268
CML (513) 569-7562
FTS 8-684-7562

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Air
Environmental
Engineering
and
Technology
Demonstration
Hazardous Air Pollutant Regulatory
Activities

The engineering program for hazardous air
pollutants addresses problems in the industrial,
commercial, governmental (e.g., military), and
public sectors. The program is comprised of four
parts: (1) prevention of Hazardous Air
Pollutant/Volatile Organic Compound emissions;
(2) assessment and enhancement of existing
control devices; (3) development and
demonstration of innovative new prevention and
control approaches; and (4) direct engineering
technical support.
  Prevention of HAP/VOC emissions is
accomplished through development of engineering
strategies involving the use of such options as:

—Substitutes
—Alternative feedstocks and processes
—Recovery, reclamation, reuse
—Decision-making systems for product
  manufacturers and formulators
—Special prevention techniques

  Enhanced control of HAP, VOC, and PM-10
involves improving existing controls as well as
developing and evaluating new, high-tech control
technologies. Such new, advanced technologies
may make control possible where it was not
feasible before, e.g., small point and area sources.
The program also involves work with source-
oriented controls for problem sources such as
woodstoves and municipal waste incinerators.
  An important component of the program is the
assessment and enhancement of existing types of
generic air toxic control such as carbon adsorption,
catalytic oxidation, and particle controls. In
addition, new technologies such as the corona
destruction process will be developed and assessed.
  Technical support includes direct support to
state and local agencies and EPA Regional Offices
through operation of the Control Technology
Center. It also includes source assessment (source-
related measurements) to help define the
magnitude and character of air toxic emissions,

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Air
                      especially as related to application of prevention
                      options and controls.

                      Office or                     Total      Percent
                      Laboratory    Contact          Funds ($k)  In-House

                      AEERL/RTP    Wade Ponder       3,837.7       40
                      OEETD/HQ    Marshall Dick       241        75
                      Hazardous Air Pollutant Regulatory
                      Activities

Health Effects     The health research program for hazardous air
                      pollutants (HAPs) has three goals: (1) to develop
                      and validate techniques to evaluate the toxic
                      effects of HAPs, (2) to produce dose-response data
                      on the toxic effects of HAPs, and (3) to develop
                      methods which improve our ability to use
                      toxicological data in performing risk assessments.
                        Research is conducted on effects associated with
                      specific chemicals, chemical classes and complex
                      mixtures.
                        More broadly, there is a need to evaluate
                      whether prolonged exposures to ambient levels of
                      potential HAPs pose a significant health risk.
                      Primary research approaches are animal
                      toxicology and dosimetry studies. EPA researchers
                      will develop methods to provide data on the
                      genetic, developmental, and neurotoxic effects of
                      HAPs. Emphasis of this research will be on the
                      toxic components of gaseous-aerosol complex
                      mixtures and source emissions. Emphasis is also
                      shifting towards research that  will resolve generic
                      extrapolation issues, such as route-to-route
                      extrapolation, and extrapolation across dose
                      concentrations and durations.
                        Dose-response data on the mutagenic and
                      carcinogenic activity and noncancer endpoints
                      including neurotoxicity, physiological, and
                      pulmonary health effects of potential HAPs will be
                      determined. These HAPs will be selected based
                      upon assessments prepared by  the Office of Health
                      and Environmental Assessment (OHEA) and
                      research needs identified by the Office of Air
                      Quality, Planning, and Standards (OAQPS). The
                      effects of selected chemicals suspected of being

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                     hazardous to the nervous system will be studied.
                     The dose-exposure research will provide
                     quantitative information on the relationship
                     between dose (body burden) and human exposure
                     to toxic pollutants.
                     Office or
                     Laboratory

                     HERL/RTP
                     OHR/HQ
            Contact

            Ila Cote
            Susan Perlin
Total      Percent
Funds ($k)  In-House
4,046.9
71.4
Modeling,
Monitoring
Systems
and Quality
Assurance
Hazardous Air Pollutant Regulatory
Activities

The need for technology to monitor non-criteria
contaminants at the regional, state, and local
levels continues. Broad-based stationary source
screening methods, generic methods and specific
methods for some of the 191 hazardous pollutants
covered in Title III of the new Clean Air Act will
be emphasized. Stationary source methods will be
evaluated and validated. In addition, certain
advanced ambient methods will be evaluated,
including cryogenic preconcentrations, gas
chromatography and Fourier transform infrared
(FTIR) spectrometry.
   To support quality assurance needs within the
program, reference samples will be developed and
maintained, guidelines for procedures will be
developed, and laboratory audits will be
performed.
   A major ORD field program, the Integrated Air
Cancer Project, will continue to study the origins
and chemical composition of individual species of
toxics, mutagenic or carcinogenic pollutants which
are present in ambient air.
   In the Characterization, Transport, and Fate
(CTF) research program, laboratory and field
studies will be conducted to determine the
atmospheric lifetimes and transformation
products of hazardous air pollutants; to determine
deposition and removal rates of hazardous
chemicals; and to identify the factors responsible
for concentration levels and spatial and temporal
(i.e., seasonal) variability of selected volatile

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Air
                     organic compounds. Also, research studies will
                     examine the atmospheric chemical and physical
                     processes that are important in producing
                     mutagenic compounds in the atmosphere. The
                     information obtained from this program is used for
                     preparing health assessment documents to
                     determine if chemicals in the atmosphere present
                     a hazard.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds (Sk)  In-House

                     AREAL/RTP   John Clements     2,927.4      50
                                 Larry Cupitt
                     OMMSQA/HQ William Keith
                     Hazardous Air Pollutant (HAP)
                     Regulatory Activities

Scientific          The hazardous air pollutant scientific assessment
Assessment       program of the Office of Health and
                     Environmental Assessment (OHEA) has four
                     major elements: (1) health assessments, (2)
                     research to improve methodologies for these
                     assessments, (3) technological/information
                     transfer, and (4) expert consultation to the Office
                     of Air and Radiation (OAR) on all the above
                     elements.  During FY91,  major emphasis will be
                     placed on implementation of programs that are
                     responsive to new requirements of the Clean Air
                     Act Amendments. The exact nature of the
                     scientific assessment program is dependent on the
                     final language of the Amendments, but even at
                     this point the assessment program can be broadly
                     structured to respond.
                        Health assessment activities will focus on the
                     list of 191 air-toxics in the Clean Air Act
                     Amendments and OAR information needs relative
                     to their decisions on negligible risk, residual risk,
                     and designation of lesser quantity cut-offs. Cancer
                     unit risks will be developed for those listed air
                     toxics that have not already been evaluated.
                     Chronic reference concentrations (RFC) will be
                     developed for non-cancer effects. As a methodology
                     for acute RFC becomes available from the research
                     program, acute RFC's will be developed. Draft

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                      RFC's are submitted to the EPA-wide Verification
                      Committee, co-chaired by OHEA. After
                      verification or determination that the data base is
                      inadequate for an RFC, the appropriate
                      information is entered into IRIS. Those listed
                      chemicals having data bases inadequate to meet
                      the criteria for RFC development will be
                      identified. OHEA will provide support to the
                      Office of Air Quality Planning and Standards
                      (OAQPS) in identifying risks for these chemicals.
                      Another aspect of the program is to complete
                      health assessment documents and other
                      documents in progress in FY90.
                        A research program is being conducted to
                      improve methodologies for risk assessment of air
                      toxics. The focus is on non-cancer health effects
                      and the  RFC methodology. The research is
                      designed to enhance the scientific foundation of
                      assumptions inherent in all assessments and to
                      increase the utility of the assessments to the
                      program offices. This involves: (1) improving the
                      quantitative bases for uncertainty assumptions in
                      the chronic RFC method so that ultimately some
                      key assumptions can be replaced with actual
                      values, (2) developing an acute RFD method, and
                      (3) developing procedures to assess risks above the
                      RfC. Based on results from this research, the RFC
                      methodology will be revised and subjected to
                      expert peer review and Agency review prior to
                      completion and EPA-wide implementation.OHEA,
                     jointly with OAQPS, operates the Air Risk
                      Information Support Center (Air RISC). This
                      Center provides information on health risks of air
                      toxics to state and local air pollution agencies as
                      well as to EPA Regions. Rapid response is
                      achieved via a hot-line operation. Numerous types
                      of technical guidance are also provided.
                        OHEA also acts as technical consultants to
                      OAR on  air toxics health issues. After the passage
                     of the Clean Air Act Amendments, this role will
                      increase as OHEA provides expert review on
                      listing/delisting decisions.

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Air
                     Office or
                     Laboratory   Contact

                     ECAO/RTP    Lester Grant
                            Total      Percent
                            Funds ($k)  In-House
                                                 3,917.6
                                        47.0
Health Effects
Mobile Source Pollutant Regulatory
Activities

The health effects research program for mobile
sources provides health effects data for selected
emissions and transformation products associated
with motor vehicles. One goal of the research
conducted by the Health Effects Research
Laboratory is to develop methods and data that
can be used to characterize the risk of mobile
source emissions as a component of the total
human exposure to carcinogens and mutagens.
Methods will be developed to apportion the
potential cancer risk from alternative engine and
fuel types. The work will include the assessment of
DNA adducts as biomarkers of exposure,
dosimetry, or cancer risk from mobile source
emissions in comparative mutagenesis and
tumorigenesis bioassay systems in vitro and in
vivo. The work also includes an examination of the
impact of alternative fuels and their emissions on
human health, with the focus on
pharmacokinetics, developmental effects,
reproductive effects, neurotoxicity and mutagenic
activity of methanol exposure.
                     Office or
                     Laboratory  Contact
                            Total      Percent
                            Funds (Sk)  In-House
                     HERL/RTP
                     OHR/HQ
            Ila Cote
            Susan Perlin
322.9
33.6
Modeling,
Monitoring
Systems
and Quality
Assurance
Mobile Source Pollutant Regulatory
Activities

The major effort in this program is to characterize
the emissions from motor vehicles using
traditional fuels as well as alternative fuels, such
as methanol, compressed natural gas or
reformulated gasoline. Laboratory studies of the
impact of ambient temperature on the emission

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Air
                      rates of regulated and unregulated pollutants
                      from light duty motor vehicles will continue.
                      Emphasis will be directed to the composition of
                      organic emissions. Studies of the relationship
                      between fuel composition, including gasoline and
                      gasoline-alcohol blends, and the composition and
                      rate of tailpipe, evaporative, and refueling
                      emissions will continue. Other programs will
                      emphasize the development of analytical
                      procedures suitable for real-time measurement of
                      motor vehicle emissions. Procedures for
                      determination of the operating condition of motor
                      vehicle emission control devices will be evaluated.
                      Programs for examination, development, and
                      improvement of procedures for apportionment of
                      observed ambient pollution to motor vehicles will
                      be conducted.
                        Studies will also be conducted to characterize
                      organic emissions from motor vehicles under
                      widely variant operating conditions, i.e.,
                      temperature, speed, and fuels. Emission rates of
                      formaldehyde, benzene, paraffins, and other
                      organic compounds of interest will be determined.
                        Research will also focus on developing
                      methodology for determining exposures of the
                      population to mobile source pollutants. A general
                      methodology has been developed for measuring
                      and modeling the exposures of the population to
                      carbon monoxide, and this methodology has been
                      successfully field tested. Future research will
                      extend this methodology to other locations and,
                      where possible, to other mobile source air
                      pollutants. Detailed analyses of human exposure
                      field data collected in selected highway
                      microenvironments will be undertaken to develop
                      improved commuter exposure models
                      incorporating traffic variables (roadway
                      type.traffic count, trip time, and seasonal
                      characteristics). Data on human activity patterns
                      and time budgets will be further evaluated for use
                      in exposure models. Improved models of human
                      activity patterns and microenvironmental
                      concentrations will be developed and field
                      tested.The Simulation of Human Activities and
                      Pollutant Exposure (SHAPE) model will be
                      modified and validated using field data from
                      another urban area. Additional testing of basic

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Air
                      assumptions incorporated in the NAAQS
                      Exposure Model (NEM) will be undertaken. The
                      purpose of the research will be to improve the
                      accuracy and reliability of the Agency's exposure
                      assessment methodology for mobile source
                      pollutants.

                      Office or                      Total     Percent
                      Laboratory  Contact          Funds ($k) In-House

                      AREAL/RTP  Ken Knapp        1,688.3       39
                                 Dale Pahl
                                 Frank Black
                      OMMSQA/HQ William Keith
                     Mobile Sources

Scientific          The Office of Health and Environmental
Assessment       Assessment (OHEA) is providing management of
                     the ORD Alternative Fuels Research Program and
                     scientific assessments of major issues related to
                     EPA's development of policies and regulations on
                     alternative fuels. OHEA is coordinating ORD
                     activities to develop a Research Strategy that
                     describes research needed to quantitatively assess
                     the human health, ecosystem, and global warming
                     effects of alternative fuels (e.g. methanol, ethanol,
                     compressed  natural gas, and reformulated
                     gasolines) compared to conventional gasoline and
                     diesel fuels.  This Strategy is intended to provide
                     broad guidance to development of targeted
                     research programs within ORD as well as other
                     scientific institutions which have an interest in
                     alternative fuels. The ORD Research Plan for
                     Alternative  Fuels is also being developed. It is
                     based on the Strategy and describes what research
                     ORD would conduct at several levels of resources.
                     Both the Strategy and the Plan will be reviewed
                     by the Science Advisory Board and by the public,
                     before the final documents are developed.
                        As part of the scientific assessment portion of
                     ORD's Alternative Fuels Program, OHEA will
                     develop assessments of key health and ecosystem
                     issues and provide overall coordination of the
                                10

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Air
                      program within and outside EPA. This will entail
                      the development of major health and ecosystem
                      assessments of the alternative fuels and gasoline.
                      These documents will be subjected to expert
                      scientific review at workshops, as well as public
                      and Science Advisory Board reviews. Assessments
                      of additional topics (i.e., accidental ingestion of
                      alternative fuels by children, the health impacts of
                      alterations in ozone levels resulting from fuel
                      switching, and predicted occurrences of large
                      accidental spills of alternative fuels into aquatic
                      systems) will also be developed, along with
                      interpretive reports of findings from the ORD
                      research program. This assessment program will
                      begin in FY91 with the initiation of one major
                      assessment.
                       Another key element is to coordinate the
                      research program with all interested scientific
                      institutions (i.e., federal, private, academic and
                      international). As one step in this process,  OHEA
                      will hold an international meeting on alternative
                      fuels in FY91, to which these institutions will be
                      invited to describe their programs and recent
                      research results, thereby substantially improving
                      communication. A proceedings of the meeting will
                      be developed.
                     Office or
                     Laboratory   Contact

                     ECAO/RTP    Judith Graham
                            Total      Percent
                            Funds ($k) In-House
                                                   267.8
                                        53.0
Modeling,
Monitoring
Systems
and Quality
Assurance
National Ambient Air Quality Standards
(NAAQS)

The purpose of this program is to provide scientific
information on atmospheric processes and
monitoring methodologies to support the Agency's
regulatory program on National Ambient Air
Quality Standards (NAAQS). The current
program will focus on inhalable particulate
matter, fine particles and acid aerosols research.
  Under the Monitoring Systems and Quality
Assurance portion of this program, improved air
pollution monitoring methods are being developed
to help determine air quality trends, support
                                11

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Air
                      compliance with standards, and meet enforcement
                      needs. The data from these methods are often used
                      as the basis for regulatory action. The areas
                      investigated include ambient methods
                      development, quality assurance guidelines and
                      audit materials preparation.
                        Ambient methods development will focus on
                      measuring particulate matter in support of
                      anticipated changes to the National Ambient Air
                      Quality Standards (NAAQS). Researchers will
                      analyze visibility data and its relationship  to mass
                      and composition data from the Eastern Fine
                      Particle Visibility Network.
                        Quality Assurance (QA) support will be
                      provided through a standard laboratory and
                      repository of quality assurance materials. Routine
                      and special audits will be conducted at
                      laboratories making ambient measurements and
                      at compressed gas vendors. QA guidelines,
                      handbooks, data handling systems and a precision
                      and accuracy reporting system will be maintained
                      and updated. QA procedures, materials, and audit
                      techniques will be developed for compliance
                      monitoring.

                      Office or                      Total      Percent
                      Laboratory  Contact          Funds ($k) In-House

                      AREAL/RTP  William Wilson     1,895.1        24
                      EMSL/LV    Marc Pitchford       171.1        29
                      OMMSQA/HQ William Keith
                      National Ambient Air Quality Standards
                      (NAAQS)

 Health Effects     This research program has three major goals: (1)
                      to provide data on health effects of exposures to
                      03, NC>2, CO, sulfur oxides, particles, acid aerosols
                      and lead using both human and animal studies; (2)
                      to provide better models to extrapolate from
                      animals to humans; and (3) to develop improved
                      test methods for research into the physiological
                      responses of humans to the primary air pollutants.
                        Health effects research is conducted to refine
                      and improve the toxicological and epidemiological
                      data base relevant to criteria pollutants. Both
                      human and animal-dose response studies, as well
                                 12

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                     as mathematical modeling, will be given special
                     attention to determine the deposition, clearance,
                     and pulmonary function effects of particles, alone
                     and in combination with ozone, NC>2 and SO2-
                        Research will be done to improve the models
                     used to extrapolate animal biochemical and
                     metabolic responses to humans. Both human and
                     animal experiments will provide data on the
                     functional, morphological, and biochemical
                     changes which occur following exposures to the
                     primary air pollutants, and provide extrapolation
                     techniques to predict human pulmonary
                     responses, including functional and
                     morphological, to gases and particles.
                        Animal, human clinical and epidemiology
                     studies will provide data to determine the extent
                     to which  the primary air pollutants cause or
                     exacerbate the development of noncarcinogenic
                     chronic disease. Effects are studied in both healthy
                     and sensitive (e.g., asthmatic) individuals.
                     Biological endpoints to be examined include
                     development of cardiovascular or pulmonary
                     disease, aggravation of existing conditions,
                     changes in biochemistry and host defense
                     mechanisms, and changes in pulmonary structure
                     or function. Emphasis is currently placed on
                     determining the acute and chronic effects of 03
                     and NC>2 inhalation.
                        The health effects data from this research
                     program are incorporated into EPA criteria
                     documents which are used to set and revise
                     National Ambient Air Quality Standards
                     (NAAQS).
                      Office or
                      Laboratory   Contact
                            Total      Percent
                            Funds (Sk)  In-House
                      HERL/RTP
                      OHR/HQ
            Ila Cote
            Susan Perlin
13,395.6
                                                              30.8
Environmental
Processes and
Effects
National Ambient Air Quality Standards
(NAAQS)
This research provides scientific support of
NAAQS by determining the effects of ozone on
forests, with emphasis on species of economic
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                      importance. Selected forest species will undergo a
                      range of ozone exposure scenarios possibly
                      experienced in the forested regions of the United
                      States. The ecophysiological impacts of ozone will
                      be studied in sensitive tree species, and studies of
                      the economic impact of ozone damage will
                      continue on economically and ecologically
                      significant forest species. The research on
                      exposure scenarios and tree responses will be used
                      to assess the risk from ozone on major
                      commercially valuable forest tree species.

                      Office or                      Total      Percent
                      Laboratory  Contact          Funds ($k)  In-House

                      ERL/COR     BillHogsett        1,860.6       40
                      OEPER/HQ   PaulRingold        1,006.8       60
                     National Ambient Air Quality Standards
                     (NAAQS)
Scientific           ^he main objective of the NAAQS scientific
Assessment        assessment program is to review and revise
                      criteria documents for sulfur oxides, particulate
                      matter, nitrogen oxides, ozone and other
                      photochemical oxidants, carbon monoxide, and
                      lead. Air Quality Criteria Documents (AQCDs)
                      are mandated by the Clean Air Act and, as
                      directed by the Act, are revised at 5-year intervals.
                      These documents are evaluations of the available
                      scientific information on the health and welfare
                      effects of criteria pollutants. As such,  criteria
                      documents are the primary source of information
                      used by EPA regulatory decision makers in setting
                      or revising the NAAQS.
                        Criteria document draft materials are
                      developed by EPA scientists and outside expert
                      consultants and are peer-reviewed by scientific
                      experts in public workshops. Subsequently, the
                      document drafts are revised and through
                      announcements in the Federal Register, the public
                      is invited to comment on the resulting external
                      review drafts, which are also reviewed in public
                      meetings by the Clean Air Scientific Advisory
                      Committee of EPA's Science Advisory Board. The
                      final documents are submitted to the Clean Air
                                14

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Air
                     Docket and are published concurrently with the
                     proposed regulatory decisions.
                        In FY91, work will continue on revision of the
                     Carbon Monoxide and Oxides of Nitrogen AQCDs
                     and on the assembling and updating of data bases
                     concerning ozone, acid aerosols, lead, and fine
                     particle-visibility relationships.
                     Office or
                     Laboratory   Contact

                     ECAO/RTP    Lester Grant
                            Total      Percent
                            Funds ($k)  In-House
                            1,975.8
57.0
Modeling,
Monitoring
Systems
and Quality
Assurance
New Source Performance Standards and
State Implementation Plans

Air quality models predicting the air quality
impacts associated with pollution abatement
strategies are used in the evaluation and
development of State Implementation Plans for
the control of photochemical oxidants, gases and
particles.
  The transport and fate portion of the program is
responsible for conducting air quality modeling
and laboratory studies to develop a single,
defensible chemical mechanism module for use in
ozone air quality standard development and
implementation. Models will be used to assess the
air quality impacts associated with various ozone
control strategy scenarios. In a cooperative
program involving ORD, the Program and
Regional offices, the Regional Oxidant Model
(ROM) will be used to assess the impact of long -
range ozone transport in the Northeast. Also in
response to questions that have been raised
concerning the role of biogenic emissions in ozone
formation in the southeastern U.S., a research
program has been initiated to determine the role
of biogenic emissions and other factors that may
affect the attainment of ozone standards.
  Field and laboratory studies to further develop
and test different source apportionment methods
(SAMs) are underway and will evaluate hybrid
SAM models with chemical composition and
meteorology for apportionment of regional
aerosols. In view of the revised particulate air
                                15

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Air
                     quality standard based on inhalable particulates,
                     field, smog chamber, wind tunnel, water channel,
                     and laboratory studies are being used to develop
                     and evaluate chemistry and dispersion
                     components of urban scale particulate air quality
                     models. Research is continuing to develop a first
                     generation regional particulate air quality model
                     (RPM).
                       Additional research in the monitoring systems
                     and quality assurance area emphasize the
                     development of monitoring methods and provision
                     of quality assurance samples and support. EPA's
                     monitoring methodologies for source air pollutants
                     will include evaluation, methods improvement,
                     preparation of operating guidance and manuals
                     for developed and commercial monitoring
                     instruments. A major effort will be conducted to
                     evaluate methods for PM10 monitors. Quality
                     assurance for the source monitoring program is
                     essential to ensuring that only data of known
                     accuracy and precision are used for regulatory and
                     enforcement decisions. Reference samples will be
                     provided and audits of laboratories making source
                     measurements will be continued.
                     Office or
                     Laboratory
           Contact
Total      Percent
Funds ($k)  In-House
                     AREAL/RTP  John Clements
                                Jack Shreffler
                                Francis Schiermeier
                     EMSL/LV    James McElroy
                     OMMSQA/HQ William Keith
                           6,455.1
                             452.6
                                                            38
            43
 Environmental
 Engineering
 and
 Technology
 Demonstration
New Source Performance Standards and
State Implementation Plans

Research in this program supports the
development of New Source Performance
Standards (NSPS) and State Implementation
Plans by aiding in the development of pollutant
control technology which is cost-effective and
energy-efficient. The focus of the research is on the
reduction of Volatile Organic Compounds, NOX,
and SOX emissions.
   Volatile Organic Compounds (VOCs) are a
major cause of non-attainment of the National
                                16

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Air
                      Ambient Air Quality Standards for ozone.
                      Extramural research will evaluate VOC
                      abatement technology such as adsorption, thermal
                      oxidation, and catalytic oxidation. Of particular
                      interest will be effective and affordable prevention
                      and control methods for small VOC-emitting
                      industries.
                        Combustion modification methods of
                      controlling NOX and other emissions will be
                      evaluated to determine combustion modification
                      (CM) methods for reducing NOX emissions and
                      improving the performance of utility and
                      industrial boilers. Prior research has proven that
                      CM methods can be effective for control of NOX as
                      well as other emissions, if each method is tailored
                      to the characteristics of the specific combustion
                      equipment (e.g., stoker or package boilers, coal or
                      oil burners, and internal combustion engines or
                      gas turbines). Research will evaluate an in-
                      furnace NOX reduction technique called reburning
                      which involves injection of fuel downstream of the
                      primary combustion zone. In-house reburning
                      experiments on pilot-scale combustors will be
                      continued and field test projects in a full-scale
                      coal-fired utility boiler will be started. In-house
                      tests of selective catalytic reduction (SCR) systems
                      for internal combustion engines will  be completed.
                        Existing technology to control gaseous
                      pollutants is expensive. For new utility sources,
                      approximately 30% of boiler costs are attributable
                      to air pollution control. Design and performance
                      data for low cost, high-reliability emission
                      reduction technology are needed to support the
                      Agency's regulatory functions. Technical support
                      to regulated entities will be provided by
                      conducting assessments and fundamental
                      research on technologies for reduction of stack
                      emissions of sulfur dioxide (SC^).
                        SOX emissions reduction technology will focus
                      on demonstrating dry sorbent injection technology
                      with its potential for 55 to 70 percent control and
                      also on an advanced process that can be coupled
                      with sorbent injection to efficiently utilize
                      unreacted sorbent and provide for 90 percent SC>2
                      control. These processes will be suitable for both
                      retrofit and new applications and will be
                      candidates for consideration in acid rain control
                                 17

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Air
                      implementation strategies. A coordinated in-
                      house and extramural pilot-scale effort will
                      provide essential direct support to the technology
                      demonstration programs especially in the area of
                      sorbent reactivity and process optimization. These
                      efforts will provide test data which will be used to
                      design key process equipment for the advanced
                      SC>2 removal process. Quality technology transfer
                      will continue to be given high priority to ensure
                      that results of the SC>2 control program are
                      expeditiously and effectively made available to
                      potential users for consideration in their
                      implementation strategies.

                      Office or                      Total     Percent
                      Laboratory   Contact           Funds ($k) In-House

                      AEERL/RTP  Jim Abbott         2,448.6       54
                                  Everett Plyler
                      OEETD/HQ   Marshall Dick        281.1        90
                      Indoor Air Pollution Activities

Scientific          EPA's indoor air research program is geared to
Assessment        identify, characterize, and rank indoor air
                      problems, and to assess and implement
                      appropriate mitigation strategies. EPA's research
                      and analytical activities will pursue both source-
                      specific and generic approaches to indoor air
                      pollution. From a source-specific standpoint, the
                      Agency will identify high-risk pollutant sources
                      and characterize the exposures and health risks of
                      various populations to those sources. At the same
                      time the Agency will also pursue broad, cross-
                      cutting strategies to assess the total exposure of
                      people to indoor air pollutants and to develop
                      mitigation strategies that can address multiple
                      pollutants simultaneously through improved
                      building design and management techniques.
                        Activities in FY91 in the area of scientific
                      assessment include the continued development of
                      risk characterization methodology to assess
                      noncancer health effects; develop and apply
                      methods to assess exposures to both single
                      compounds and mixtures; continue comprehensive
                      review of biocontaminants in indoor air; develop
                      portable, comprehensive test kit for initial
                                 18

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Air
                      screening of indoor air quality problems; update
                      and publish Indoor Air Reference Bibliography.

                      Office or                      Total      Percent
                      Laboratory   Contact           Funds ($k)  In-House

                      ECAO/RTP    Michael Berry       775         39.0
                      Indoor Air Pollution Activities

Health Effects    The goal of the indoor air health effects research
                      program is to determine whether exposure to
                      indoor air pollution contributes or leads to adverse
                      health effects. Indoor air often contains higher
                      levels of pollutants than outdoor air. Most
                      individuals spend over 80% of their time indoors.
                      Sensitive populations, e.g., children, asthmatics,
                      and the elderly, may be at higher risk from
                      exposure to indoor air pollution. Therefore, the
                      exposure, dose, and effects from indoor air
                      pollution need to be factored into the total risk
                      assessment of air pollution.
                        A balanced program  involving humans,
                      laboratory animals, and bioassay approaches will
                      be maintained to better understand "sick building
                      syndrome." The approach to study the effects of
                      indoor air is broad. Genetic bioassay studies of the
                      combustion products from indoor air sources,
                      including environmental tobacco smoke and
                      kerosene heaters, will be conducted in chambers,
                      test homes, and targeted field studies to provide a
                      comparative estimate of the potential cancer risk
                      from various sources. Human clinical studies of
                      volatile organic compounds will continue to be
                      conducted in chambers to determine effects related
                      to the "sick building syndrome." Field and clinical
                      studies will continue to evaluate cotinine as a
                      biochemical marker for nicotine Work will be
                      conducted to start characterizing people with
                      chemical hypersensitivities. This work will be
                      critical to understanding the physiological basis
                      for multiple chemical sensitivity.
                                 19

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Air
                     Office or
                     Laboratory   Contact
                     HERL/RTP
                     OHR/HQ
            Ila Cote
            Susan Perlin
                            Total      Percent
                            Funds ($k)  In-House
1,135.6
5.5
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Indoor Air Pollution Activities

Indoor air research consists of development and
testing of monitoring devices and the design and
implementation of field studies to identify and
quantitate pollutants indoors. This research
supports investigation of pollutant sources,
human exposures and health effects.
  Methods development research investigates
monitoring devices for pollution monitoring levels
in homes. Results are used to produce information
regarding proper use (sample locations and sample
times) and performance limitations of these
devices. This research will continue to develop and
test these devices, especially personal monitors, in
other microenvironments (buildings, vehicles,
etc.).
  Field studies to investigate spatial and
temporal variations in indoor air quality will be
designed and implemented in conjunction with an
intensive review of data needs. The program will
emphasize research on "sick building" where
elevated levels of pollutants  can be observed and
will characterize the major parameter that will
influence indoor air quality.

Office or                     Total      Percent
Laboratory  Contact           Funds ($k)  In-House

AREAL/RTP  Ross Highsmith     1,189.0        9
EMSL/CIN   Alfred Dufour       200.0       45
OMMSQA/HQ William Keith         0         0
Environmental
Processes and
Effects
Global Change Research

Increased atmospheric concentrations of carbon
dioxide and other radiatively important trace
gases (methane, nitrous oxide,
chlorofluorocarbons, etc.) have raised concerns
about potential climate change among the general
                                20

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Air
                      public and members of the scientific community.
                      Additionally, concerns about decreasing
                      stratospheric ozone have emerged. Scientific
                      information on global change, including both
                      climate change and stratospheric ozone influences,
                      is required to assist decision makers in developing
                      sound policies. However, much uncertainty exists
                      about how these global changes derive from or
                      may impact specific geographic regions, ecological
                      systems, and human activities.
                        Emissions of greenhouse gases have been
                      increasing, so clearly, understanding of sources
                      and sinks must be improved, to evaluate the
                      relative contribution of anthropogenic and natural
                      sources of these gases. In addition, chemical
                      transformations that occur in the troposphere and
                      stratosphere, and which help determine the net
                      radiative forcing that results in the green house
                      effect, will be studied. Development of a second-
                      generation carbon emissions model is also
                      currently ongoing. This research, in close
                      conjunction with the Department of Energy, will
                      develop a global model capable of handling
                      emissions scenarios with more sophistication than
                      is currently available, allowing more realistic
                      assessment of the consequences of making specific
                      changes in emissions rates.
                        Ecological effects are important potential
                      consequences of climate change. Research into
                      these potential effects is ongoing, with a focus on
                      the relation between climatic conditions and
                      boundaries between major ecosystems, such as
                      between forests and grasslands. When completed
                      this research should provide insight for resource
                      managers into the magnitude of latitudinal and
                      longitudinal shifts of major ecosystems that might
                      be associated with specific climatic changes.
                        Another important research effort is the
                      investigation of effects of decreasing stratospheric
                      ozone that allows increased ultraviolet flux (UV-B)
                      at the earth's surface. Research conducted under
                      the Agency's stratospheric ozone depletion
                      program will continue on terrestrial and aquatic
                      ecosystems, human health, and emissions and
                      mitigative solutions. Studies of the effects of UV-B
                      radiation on terrestrial ecosystems will emphasize
                      determining the relationship between UV-B dose
                                 21

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Air
                      and other anthropogenic factors such as global
                      climate change. Research will also stress UV-B
                      effects on the marine food web and biogeochemical
                      cycling. Further evaluation will be made of
                      alternative compounds to CFCs and halons, and in
                      technologies to replace those used for such
                      purposes as refrigeration, insulation, and fire
                      extinguishment. Research will also continue on
                      developing ways to reduce emissions of chemicals
                      that contribute to stratospheric ozone depletion,
                      including CFCs, halons, and nitrous oxide, and to
                      transfer technology within the U.S. and to
                      developing nations. Support for the Vienna
                      Convention for the Protection of the Ozone Layer
                      and the renegotiated Montreal Protocol will
                      continue, in cooperation with other nations.
                         While research on potential causes and
                      consequences of global change is important,
                      research on possible options for adapting to or
                      mitigating change is also important.
                      Opportunities exist for technological advances,
                      such as intensive reforestation, and other
                      sequestration and biomass utilization techniques
                      to replace fossil fuels. The potential for reducing
                      greenhouse gas emissions will also be a major
                      focus of ORD. These technologies include
                      biological approaches for methane and  nitrogen
                      oxides as well as novel control/utilization
                      techniques for methane.
                      Office or
                      Laboratory

                      OEPER/HQ
                      AREAL/RTP
                      AEERL/RTP

                      ERL/ATH

                      ERL/COR

                      ERL/NARR
Contact

Anthony C. Janetos
Robert C. Worrest
John T. Sigmon
Jack H, Shrefler
James H. Abbott
William J. Rhodes
Richard G. Zepp
Lee A. Mulkey
David T. Tingey
Peter A. Beedlo\v
Henry A. Walker
Henry Lee II
Total
Funds ($k)

26,000
Percent
In-House

   13
                                  22

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Air
 Environmental
 Engineering
 and
 Technology
 Demonstration
Global Climate Change

As a result of increased national and international
concern regarding potential significant changes in
global climate, OEETD has expanded its program
in this area. The expanded global emissions and
control program, which is an integral part of the
ORD program, consists of two major elements:
emissions and mitigation. Emissions research
includes development of global and regional
emission factors, activities, and functions for
anthropogenic and biogenic sources of radiatively
important trace gases. The mitigation program
includes assessment of emissions management
techniques and their applicability to
industrialized and developing countries, and
selected development and demonstration of
promising techniques to accelerate their
commercialization and application to reduce
emissions of radiatively important trace gases.
Initial mitigation activities will center on
technology to reduce anthropogenic emissions of
methane  (e.g., from coal mines, landfills, and
natural gas systems) and on biomass utilization.
The biomass utilization research will focus on
harvesting, preparation, and combustion of
biomass fuel and sequestration of biomass in
useful products.
                     Office or
                     Laboratory

                     AEERL/RTP
                     OEETD/HQ
            Contact

            David Mobley
            Marshall Dick
Total      Percent
Funds ($k)  In-House
4,500.00
            10
Health Effects
Health Effects Institute

A significant part of the health effects research on
mobile source emissions is conducted through the
Congressionally mandated Health Effects
Institute (HEI). HEI is jointly sponsored by EPA,
through extramural funding, and the automobile
industry to perform research on the health effects
of pollutants related to mobile sources.
  The research focuses on various mobile source-
related pollutants, including carbon monoxide,
oxidants (ozone and nitrogen dioxide), diesel
                                23

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Air
                      exhaust and alternative fuels such as methanol.
                      Important areas of health research conducted by
                      HEI include: development and use of biological
                      markers; identification and characterization of
                      susceptible populations; determination of dose to
                      target tissue; assessment of susceptibility to
                      infection; examination of mechanisms of injury
                      and/or disease; and evaluation of
                      neurotoxicological and behavioral effects. HEI is
                      expanding its research on the health effects of
                      alternative fuels by sponsoring several methanol
                      inhalation studies in rats and monkeys that focus
                      on metabolism, pharmacokinetics, and behavioral
                      developmental effects of offspring exposed in
                      utero.

                      Office or                      Total     Percent
                      Laboratory   Contact           Funds ($k) In-House

                      HERL/RTP    IlaCote           3,000.0        0
                                 24

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Drinking Water
Health Effects
Health Effects of Drinking Water
Contaminants

This research program provides dose-response
data on organic and inorganic contaminants found
in drinking water. In addition, toxicological
methods are developed and validated for the
purpose of improving the relevance of toxicological
data to regulatory issues and to improve the risk
characterization process.
  Research will focus on determining the health
effects resulting from exposure to chlorine
disinfectants and their by-products. Work will be
done to improve methods for extrapolating health
effects research data in order to assess the risks
associated with simultaneous exposure to multiple
chemicals in binary and complex mixtures.
Epidemiology studies on the relationship between
disinfectants and cancer, and reproductive effects
will be conducted.
                     Office or
                     Laboratory

                     HERL/RTP
                     OHRAIQ
            Contact

            Jack Fowle
            Rebecca Calderon
Total      Percent
Funds ($k)  In-House
6,263.2
            53.4
 Scientific
 Assessment
Health Effects of Drinking Water
Contaminants

Revision of national drinking water regulations
and health advisory guidance given to the States
requires an assessment of the potential hazard to
human health from exposure to chemicals in
drinking water. The health assessment documents
prepared under this program take the form of both
criteria documents and health advisories. These
documents are assessments of the health effects of
exposure to contaminants in drinking water. They
specifically evaluate the relevant scientific data
describing the physical and chemical properties,
the pharmacokinetics, the health effects in
animals and humans, and the mechanisms of
toxicity. The health assessments are prepared for
various chemicals as requested by EPA's Office of
Drinking Water (ODW). This risk assessment
                                25

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Drinking Water
                     process enables ODW to establish a Maximum
                     Contaminant Level Goal (MCLG), representing a
                     level designed to preclude the risk of an adverse
                     effect on human health.
                     Office or
                     Laboratory  Contact
                           Total      Percent
                           Funds ($k)  In-House
                     ECAO/CIN   Cynthia Sonich-Mullin  931.2
                                       71.2
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Ground Water Research

Geophysical research will be conducted for
mapping and monitoring fluid movement from
injection wells; for detecting near-surface
contamination from abandoned wells and
movement along fracture zones; and, for the
evaluation of seismic hazards associated with the
underground injection process. In support of EPA's
Wellhead Protection Program, guidance on
monitoring system design will be developed.
Additional research will involve  the
quantification of the spatial characteristics of
pollutants in drinking water and the application of
modeling techniques to assist in groundwater
quality sampling decisions, including methods for
using the Geographic Information System (GIS)
for enhancing data management and analyses.
                     Office or
                     Laboratory
           Contact
Total      Percent
Funds ($k)  In-House
                     EMSL/LV    Robert Snelling
                     OMMSQA/HQ TomPheiffer
                           1,067.7
            35
 Environmental
 Processes and
 Effects
Ground Water

Ground water is a major source of drinking water
for the nation. This research program provides
both technical information and improved methods
for predicting contamination movement and
transformation. The research focuses on methods
development for and studies of subsurface
transport and fate processes such as biological
transformation, oxidation-reduction, hydrolysis,
                               26

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Drinking Water
                     and ion exchange. Facilitated transport research
                     will address complex mixture processes such as
                     multiphase transport and solvent composition
                     effects on sorption. In addition, micelle- and
                     DOC/colloid-aided transport will be addressed.
                     The results of the research will allow better
                     human exposure assessments from ground-water
                     contamination. This research is closely
                     coordinated with that in Hazardous Waste,
                     Superfund, and Pesticides.
                       Field evaluation of techniques for determining
                     the mechanical integrity and adequacy of
                     construction of injection wells will occur. Work to
                     develop technological alternatives for regulating
                     Class V wells will continue.
                       Methods will be developed for delineating
                     wellhead protection areas and for performing risk
                     assessments in wellhead protection areas.  In
                     addition, technology transfer activities associated
                     with this and other programs will be emphasized.

                     Office or                      Total      Percent
                     Laboratory  Contact          Funds ($k)   In-House

                     RSKERL/ADA James McNabb      3,733.2       35
                     OEPER/HQ   Barbara Levinson     840.2       61
                     ERL/ATH    LeeMulkey         309.2       22
 Environmental
 Engineering
 and
 Technology
 Demonstration
Drinking Water Technology

This program supports the revisions in the
National Drinking Water Standards. Technology
performance and cost data, to support maximum
contaminant standards under the Safe Drinking
Water Act and its Amendments, is obtained
through ongoing treatment research and
evaluations.
  Focus is on treatment to control physical and
chemical contaminants and microbiological
contamination. Research in treatment technology
addresses removal of: disinfection byproducts and
their precursors, inorganic contaminants,
maintaining water quality in the distribution
system, and developing supporting cost data.
                                27

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Drinking Water
                       Major treatment occurrence issues include:
                     • Assessing formation mechanisms and
                       conditions for disinfection byproducts.

                     • Evaluating control techniques for the
                       byproducts.
                     • Developing and evaluating technology for small
                       systems, including point-of-use/point-of-entry
                       treatment device evaluation.

                     • Evaluating alternative disinfection processes.

                     • Evaluating technology on corrosion of lead and
                       copper.

                     • Investigations into means of reducing lead in
                       hard and soft drinking water.

                     • Evaluation of point-of-entry systems for radon
                       removal and inactivation of crytosporidium
                       oocysts.

                     • Developing cost information for treatment
                       processes and entire systems. Evaluations will
                       also be made of the tradeoffs in planning for
                       rehabilitation of older water systems.
                     Office or
                     Laboratory   Contact
                     RREL/CIN
                     OEETD/HQ
            Robert Clark
            Bill McCarthy
Total
Funds ($10

5,400
Percent
In-House

  63
Modeling,
Monitoring
Systems
and Quality
Assurance
Drinking Water Technology

This program will provide support for the Agency-
wide mandatory quality assurance program. The
ten regional laboratories will be evaluated
annually in support of the National Interim
Primary Drinking Water Regulations monitoring
certification program. This program will also
conduct methods development research for
analytical procedures to produce precise and
accurate total measurement systems for chemical,
radiochemical and microbiological analysis, and
will investigate the application of innovative
technologies to the analysis of drinking water
contaminants. It will provide technically and
economically feasible analytical procedures to
                                28

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Drinking Water
                     monitor contaminants for use by the Agency,
                     States, municipalities, and operators of public
                     drinking water systems.

                     Office or                    Total      Percent
                     Laboratory   Contact         Funds ($k)  In-House

                     EMSL/CIN    Thomas Clark      2,648.4       60
                     EMSL/LV     Robert Snellmg       336.3       95
                     OMMSQA/HQ  Tom Pheiffer
                               29

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Water Quality
Modeling,
Monitoring
Systems
and Quality
Assurance
Water Quality Based Approach/Permitting

The monitoring research program develops
chemical, physical, and biological methods for
measuring site-specific and ambient water
pollutant concentrations and biological integrity
of ecosystems.
  Research emphasizes new measurement
method standardization and development of
quality assurance support such as guidelines,
calibration materials, performance audits, and
performance criteria. Additionally, research seeks
to extend the sensitivity of chemical methods for
measuring toxic chemicals in water and sediment.
Research on biological monitoring methods also
includes developing methods which screen toxic
concentrations of pollutants in ambient waters
and sediments; and bioassessment methods of
exposure rather than identifying specific
substances. Quality assurance procedures for
chronic and acute toxicological effects monitoring,
standardization of biological sampling and
assessment, and analysis methods are provided.
Research on physical measurement methods
concentrates on documenting the validity and
accuracy of sampling and analysis regimes. The
quality assurance program which provides quality
control calibration materials and procedures for
standardization of chemical and biological
analysis also conducts two audits of analytical
methods performance yearly.
                     Office or
                     Laboratory  Contact

                     EMSL/CIN   James Lazorchak
                                William Budde
                                John Winter
                     OMMSQA/HQ TomPheiffer
                            Total      Percent
                            Funds ($k) In-House
                            1,058.4
95
 Environmental
 Processes and
 Effects
Water Quality Based Approach/Permitting

A water quality-based approach to pollution
control provides for correction of ambient water
quality problems that remain after mandated
pollution control technology (e.g., secondary
treatment, effluent guidelines) is in place. This
                                30

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Water Quality
                     requires the ability to translate water quality
                     standards into specific effluent conditions and
                     discharge limitations for municipalities and
                     industries. Research will be undertaken to provide
                     the necessary information and scientific tools,
                     including: water quality criteria development/
                     modification protocols; contaminated sediment
                     assessment techniques; wasteload allocation
                     techniques; and complex effluent testing
                     procedures. Research on the water quality
                     functions of wetlands, and cumulative effects of
                     wetlands loss and the impacts of mitigation of
                     wetlands will also be conducted. Studies on
                     sustainable agriculture and its effect on water
                     resources will begin.
                     Office or
                     Laboratory   Contact
                            Total
                            Funds ($k)
ERL/ATH
ERL/COR
ERL/DUL
ERL/NARR
OEPER/HQ
John Rogers
Tom Murphy
Nelson Thomas
Norbert Jaworski
ChiehWu
970
653.1
3,244.4
1,790
2,546.3
Percent
In-House

   82
   82
   80
   68
   25
 Scientific
 Assessment
Water Quality Based Approach/Permitting

EPA's overall research program with regard to
water quality emphasizes development of the
scientific and technical base to help States develop
site-specific standards and to conduct use-
attainability analyses. The scientific assessment
program will provide guidance for assessing the
risk of human exposure to mixtures of toxic
chemicals, and evaluate site-specific health
hazards as required by the States and EPA. As a
part of this effort, EPA develops documentation for
the specific risk assessments.
Office or                     Total
Laboratory Contact            Funds ($k)
                     ECAO/CIN   Cynthia Sonich-Mullm  399.7
Percent
In-House

  85.4
 Modeling,
 Monitoring
 Systems and
 Quality
 Assurance
Industrial Wastewater Treatment
Technology
Research will support the Agency in the
implementation of technology-based effluent
limitation regulations and the modification of
                                31

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Water Quality
                     enforcement activities as required by water
                     quality-based permit adjustments. Methods
                     standardization research will be directed to the
                     improvement of precision, accuracy, and method
                     detection limits of existing regulated inorganic
                     and organic contaminants and biological limits.
                     Research will also validate and correct analytical
                     and biological methods for the analysis of high
                     priority industrial wastewater components as well
                     as evaluate alternative analytical methods to
                     support the National Pollution Discharge
                     Elimination System (NPDES) program.
                        Quality assurance activities include
                     conducting both the target survey and full audit of
                     some 7,000 major NPDES permits for the annual
                     Discharge Monitoring Report Quality Assurance
                     (DMRQA) study; maintenance of a repository for
                     distribution of calibration, quality control, and
                     performance evaluation samples; and the conduct
                     of performance evaluation studies. The research
                     program will support NPDES quality assurance
                     by providing quality control chemical and
                     biological samples and protocols and by
                     maintaining the standards repository, including
                     auditing monitoring systems data reliability,
                     DMRQA, and documentation of precision and
                     accuracy.
                     Office or
                     Laboratory   Contact

                     EMSL/CIN    James Lazorchak
                                 William Budde
                                 John Winter
                     OMMSQA/HQ  Tom Pheiffer
                           Total      Percent
                           Funds ($k) In-House
                             848.4
98
 Environmental
 Engineering
 and
 Technology
 Demonstration
Wastewater Treatment Technology

The wastewater technology research program
provides the technical information and
engineering assistance needed to develop and
implement the regulations and guidance for
disposal of sludge and control of pollution from
municipal treatment plants to bring plants into
compliance with state discharge permits. This
program also provides the research in industrial
wastewater characterization and control
                                32

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Water Quality
                     technology needed to support the National
                     Pollutant Discharge Elimination System. The
                     program focuses on toxicity reduction evaluations
                     to support the development of water quality-based
                     permit limitations in municipal wastewaters, and
                     best conventional technology and best available
                     technology limitations in industrial wastewaters.
                     Design, cost and performance information for
                     sludge stabilization, pathogen reduction, and
                     dewatering processes will be proved to support
                     sludge regulation implementation and
                     refinement. Emphasis is also on supporting the
                     new wastewater treatment technologies
                     development and infrastructure protection,
                     particularly with regard to small communities.
                                                 Total     Percent
                                                 Funds ($k) In-House
Office or
Laboratory
RREL/Cin
OEETD/HQ
Contact
SubhasSikdar
Don Tang
                                                 5,777.0
                                       40
Environmental
Processes and
Effects
Wastewater Treatment Technology

This research will identify and determine
distribution of unlisted chemicals in industrial
wastewaters. Compounds that can be identified by
empirical mass spectra matching as well as those
that elude identification by this technique will be
included. This research will also study the
biological functions of constructed wetlands in the
treatment of wastewater from small communities
and acid mine drainage.
                     Office or
                     Laboratory

                     ERL/ATH
                     ERL/COR
                     ERL/DUL
                     OEPER/HQ
           Contact

           William Donaldson
           Richard Olson
           William Sanville
           ChiehWu
Total
Funds ($k)

 152.2
  85.4
  90.4
Percent
In-House

  100
    0
    0
 Health Effects
Wastewater Treatment Technology

Health effects research focuses on human health
aspects of municipal wastewater and sludge
                                33

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Water Quality
                     disposal. The data from these studies are used by
                     the Agency for formulation of regulations,
                     permits, and guidelines under the Clean Water
                     Act. One emphasis, at present, is on land use and
                     disposal of municipal sludges which requires
                     careful assessment of the effects on human health
                     of exposure to pollutants contained in the sludges.
                     Research will focus on developing and validating a
                     battery of short-term tests for predicting the
                     potential health effects from exposure to complex
                     mixtures in wastewaters and sludge.
                     Office or
                     Laboratory   Contact
                            Total     Percent
                            Funds ($k) In-House
                     HERL/CIN
                     OHR/HQ
           Jack Fowle
           Rebecca Calderon
362.4
           100
 Scientific
 Assessment
Wastewater Treatment Technology

The scientific assessment program provides
human risk assessment methodologies for
chemicals and pathogens in support of regulatory
decision making on the use and disposal of
municipal sludge.  Numerical criteria and/or
management practices for pollutants in sludge are
developed based on the human risk assessment
methodologies. The use and disposal options are
landfilling, land application (including
distribution and marketing), incineration, ocean
disposal, and surface impoundment.
                     Office or
                     Laboratory Contact
                            Total     Percent
                            Funds ($k) In-House
                     ECAO/CIN  Cynthia Sonich-Mullin  367.8
                                        31.0
Environmental
Processes and
Effects
Marine, Estuaries, and Lakes

This program has three components: ocean
disposal, coastal waters, and Great Lakes.
  To support ocean disposal permit decisions,
there is a need to provide decision makers with
rationale and procedures which are scientifically
sound. These should provide guidance for the
acquisition of information and the interpretation
                                34

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Water Quality
                     of this information in order to support ocean
                     disposal permit decisions. Under the ocean
                     disposal research program, emphasis will be given
                     to the development and testing of procedures to
                     better evaluate the impacts of ocean disposal
                     actions; development of procedures to satisfy
                     monitoring needs for permit, surveillance, and
                     hazard assessment application; and development
                     of procedures for predicting the bioaccumulation of
                     contaminants and evaluation of the significance of
                     bioaccumulation processes, resultant tissue
                     residues and biological effects.
                       Methods for better source control decisions in
                     the NPDES and construction grants program are
                     needed for estuaries and near coastal waters.
                     Emphasis will be given to the development/testing
                     of biomarker assessment methods, development of
                     wasteload allocation models for estuaries, and
                     studies of ecosystem recovery.
                       The Great Lakes research program will
                     measure, describe and predict the distribution,
                     movement, fate, and effects of toxic substances in
                     nearshore "areas of concern" identified by the
                     US/Canada Water Quality Agreement. Emphasis
                     will be given to problems involving in-place
                     pollutants and mass balance modeling This
                     program will also provide the International Joint
                     Commission (IJC), the Great Lakes National
                     Program Office (GLNPO), EPA Regions and Great
                     Lakes states with technical support and research
                     data synthesis related to activities under the
                     US/Canada Water Quality Agreement.
                     Office or
                     Laboratory   Contact
ERIVNARR
ERL/GB
ERL/DUL
OEPER/HQ
Norbert Jaworski
Rod Parish
Oilman Veith
Sam Williams
3,742.9
210.9
1,787.7
400.1
                            Total      Percent
                            Funds ($k)  In-House
                                                              80
                                                              75
                                                              25
                                                              45
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Marine, Estuaries, and Lakes

The aim of this program is to develop, evaluate,
and validate standardized chemical, biological and
microbiological methods for the analysis of
contaminants and biological integrity in marine,
                                35

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Water Quality
                     estuarine and other salt water matrices. The
                     nearand coastal areas of the U.S. are economically
                     some of our richest and most sensitive ecosystems.
                     Standardized methods are needed by the Regions
                     for the National Estuaries Program and other
                     activities.
                        Currently, EPA does not have standardized
                     methods and reference materials for monitoring,
                     assessment and regulation of chemical
                     constituents and pollutants in marine and
                     estuarine waters and sediments.
                        Available methods will be reviewed for
                     applicability in marine and estuarine
                     environments and revised as necessary. Methods
                     not applicable will be modified or new methods
                     development initiated, as needed, using state-of-
                     the-art technology. On- going methods
                     development activities and plans for new methods
                     research will be reviewed and modified, if
                     appropriate, to include marine and estuarine
                     methods. Research will be conducted to determine
                     the applicability of existing nutrient, metal, trace
                     elements, and biological materials for use as
                     quality control and performance evaluation
                     samples. Application of these quality assurance
                     materials to marine and estuarine waters will be
                     coordinated with the Regions and the ORD Office
                     of Environmental Processes and Effects' marine
                     laboratory.

                     Office or                     Total     Percent
                     Laboratory   Contact          Funds ($k) In-House

                     EMSL/CIN    Thomas Clark        704.0       60
                     OMMSQA/HQ TomPheiffer
                                36

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Hazardous Waste
 Environmental
 Engineering
 and
 Technology
 Demonstration
Alternate Technologies

The Treatment program examines both existing
and emerging alternative techniques for treating
or detoxifying hazardous materials. Emphasis
continues to be placed on those waste streams
which will be banned from land disposal facilities.
  Research and demonstration of existing and
emerging technologies will be conducted for those
waste streams assigned high priority by OSWER,
waste streams which are difficult to cost-
effectively treat by available technology, and
waste streams with high potential for hazardous
air emissions. Emphasis will be on
characterization and pilot-scale testing of newly
listed hazardous waste streams. Assistance in the
review of permits for alternative technologies and
project monitoring for evaluation of such
technologies will be provided. Other types of
information transfer activities such as workshops,
seminars, and guidance documents will be
prepared in conjunction with the Center for
Environmental Research Information.
  A major portion of the research is now devoted
to reducing the production of pollutants at their
source. Major investigation will be conducted to
define assessment techniques to measure the
reduction in quantities of pollutants produced and
to identify potential areas for pollutant reduction.
Evaluation of technologies for reducing the
pollutants discharged will be conducted.
                     Office or
                     Laboratory   Contact
                           Total      Percent
                           Funds ($k)  In-House
                     RREL/Cin
                     OEETD/HQ
           R. Hill
           C. Brunner
           H. Freeman
           B. Krishnan
7,951.9
 500
20
33
 Environmental
 Engineering
 and
 Technology
 Demonstration
Incineration

The incineration research program focuses on the
problem areas of organic destruction and metals
partitioning and industries characterizing
performance of existing thermal technologies;
developing methods of rapid cost-effective
                               37

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Hazardous Waste
                      compliance monitoring of these facilities;
                      characterizing the products of incomplete
                      combustion and their formation and destruction
                      and control conditions; and developing methods to
                      predict performance to avoid process failure and
                      control process reliability. In addition, technical
                      assistance on specific regulatory or remediation
                      requirements is provided.The research is
                      conducted at laboratory-, pilot-, and full-scale
                      operations which simulate actual
                      incineration/boilers/kilns. Pilot-scale facilities are
                      located at Research Triangle Park and Jefferson,
                      Arkansas. The hypotheses from this program are
                      verified in full-scale field tests. The program
                      examines conventional incineration as well as
                      high temperature industrial processes.
                        Research on the incineration of municipal
                      waste will also be conducted to determine the
                      effectiveness of the process in destroying the
                      hazardous components of the waste and to
                      determine the characteristics of the ash produced.

                      Office or                      Total      Percent
                      Laboratory   Contact          Funds ($k)  In-House

                      RREL/CIN     C. Dempsey        1,012.9        33
                      AEERL/RTP   R.Hall             300.0        100
                      OEETD/HQ    B. Krishnan         200.0        100
                      Incineration

 Health Effects     Research on this issue focuses on improving the
                      assessment of risks from emissions and residuals
                      of hazardous waste management practices,
                      especially incineration. Current efforts are focused
                      on research to explore the relationship between
                      exposure to disposed incineration residuals
                      containing metals and dose to target tissues. This
                      pharmacokinetics research improves our
                      understanding of the principles governing
                      dosimetry of metals for risk assessment.

                      Office or                     Total      Percent
                      Laboratory   Contact          Funds ($k) In-House

                      HERL/RTP    Robert Dyer         876.8      54
                      OHR/HQ     Thomas Miller
                                 38

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Hazardous Waste
Environmental
Engineering
and
Technology
Demonstration
Land Disposal

With regard to land disposal, synthetic and clay
liners will be studied and the effectiveness of
alternative closure and monitoring procedures for
surface impoundments will be investigated.
Technical Resource Documents will be updated for
use by regional and state agencies for permitting
hazardous waste disposal facilities and for
enforcing applicable regulations. This program
will update documents for disposal facility design,
operation, maintenance, and closure.
  Research is also being conducted to characterize
air emissions from hazardous waste treatment,
storage, and disposal facilities and to assess
methods to control them.
                     Office or
                     Laboratory   Contact
                     RREL/CIN
                     OEETD/HQ
            R. Landreth
            B. Krishnan
Total
Funds ($k)

2,377.0
 100.0
Percent
In-House

   31
  100
Environmental
Engineering
and
Technology
Demonstration
Pollution Prevention

The Pollution Prevention Research Program
supports the development and demonstration of
low and non-waste production technologies, and
encourages the development of products that do
not present environmental problems relevant to
their manufacture, use, and disposal. The overall
goal of the program is to support the adoption of
techniques and technologies that result in the
elimination of pollution at the source of its
production, as opposed to controlling pollution
through increasingly stringent treatment options.
  Major elements of the program include a
program to demonstrate innovative waste
reduction technologies carried out in cooperation
with state and local waste reduction programs, a
program to encourage the adoption of pollution
prevention techniques in other federal agencies,
and a program to encourage the use of waste
minimization assessments to identify waste  .
reduction opportunities at industrial sites. This
last program has produced a generic assessment
                               39

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Hazardous Waste
                     manual and pollution prevention guides in seven
                     industries.
                        Future activities under the PPRP will highlight
                     socioeconomic studies, anticipatory research to
                     identify future opportunities for pollution
                     prevention strategies, and technology transfer.
                     Office or
                     Laboratory   Contact
                     RREL/Cin
                     OEETD/HQ
            Harry Freeman
            B. Krishnan
Total      Percent
Funds ($k)  In-House

3,500         0
Health Effects
Municipal Solid Waste

Research on the potential carcinogenic and non-
carcinogenic health effects of emissions and
residues from municipal waste combustion (MWC)
will focus on the following objectives: Perform a
comparative assessment of the mutagenicity and
carcinogenicity of the emission products from
MWC in comparison to other industrial and
residential combustion sources. Identify the
principal mutagenic/carcinogenic chemicals in
MWC emissions by using bioassay-directed
chemical characterization. Support the evaluation
of engineering and control technology parameters
by using short-term bioassays in the evaluation of
these parameters to determine operational
conditions which will minimize risk. Evaluate the
toxicity of MWC emissions, collected after
dilution, in in vivo target cell bioassays and short-
term in vivo assays.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     HERL/RTP
                     OHR/HQ
            Robert Dyer
            Thomas Miller
 895.2
            54
 Scientific
 Assessment
Municipal Solid Waste
The comprehensive risk assessment methodology
will be applied in site-specific cases. A baseline
field evaluation study of the municipal waste
combustor in Rutland, Vermont will be completed.
                                40

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Hazardous Waste
                     Work will begin on comparative risk assessment of
                     various thermal destruction options.
                     Office or
                     Laboratory  Contact
                           Total      Percent
                           Funds ($k)  In-House
                     ECAO/CIN   Cynthia Sonich-Mullin  604
                                       25.0
Environmental
Engineering
and
Technology
Demonstration
Municipal Solid Waste

ORD is expanding research in municipal solid
waste (MSW) management. Research will focus on
techniques for improving strategic planning,
source reduction recycling and improving long-
term performance of land disposal units.
Municipal waste combustion (MWC) research will
continue to provide the scientific bases for air
emission regulations; evaluation of mercury
emissions, CDD/CDF formation and gas and
heterogenous phase organic pollutant reaction;
and assess potential effects of materials recovery
on MWC processes. MWC residue research will
emphasize the environmental effects of using the
residues as useful products, sources of toxic
constituents in MSW that affect residue
characteristics, and speciation of the toxic
constituents in the ashes. MITE, ORD's program
to demonstrate and evaluate innovative
technologies for improving municipal solid waste,
will focus on demonstrating processes for
converting secondary materials into useful
commercial products.

Office or                    Total      Percent
Laboratory  Contact          Funds ($k) In-House

RREL/Cin    R. Landreth       3,933.1       35
AEERL/RTP  R. Hall           1,161.0       35
OEETD/HQ   B. Krishnan       1,000        100
Modeling,
Monitoring
Systems
and Quality
Assurance
Municipal Solid Waste Monitoring

Support is provided to the Office of Solid Waste
(OSW) to improve the siting and monitoring of
municipal waste combustion disposal facilities and
to identify key groundwater monitoring issues
                               41

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Hazardous Waste
                     pertaining to municipal waste combustion ash
                     disposal facilities.
                        The 1984 amendments to RCRA require the
                     EPA to revise, where necessary, the criteria for
                     Subtitle D facilities; however, technical
                     information in the monitoring area is needed to
                     support regulatory development. Further, in many
                     coastal areas, municipal disposal facilities are
                     located in or near wet environments, posing
                     special environmental problems. Questions
                     concerning the environmental adequacy of
                     municipal waste combustion disposal are delaying
                     the construction of needed combustion disposal
                     capacity.
                        Existing data on leachate characteristics and
                     ground-water contamination around types of
                     Subtitle D facilities and municipal waste
                     combustion ash monofils are being collected on a
                     continuous basis and evaluated. Ground-water
                     monitoring parameters for ash landfills will be
                     developed. Potential indicators of biological
                     contamination will be identified.
                        Wet environments will receive special emphasis
                     with an evaluation of siting practices relative to
                     wet environments. Methods for monitoring in or
                     near wet environments are being evaluated.
                        Existing published and unpublished
                     environmental monitoring data for environmental
                     impacts of monofil and co-disposal ash disposal
                     facilities are being identified and evaluated.
                     Existing municipal waste combustion disposal
                     facilities sites are being characterized and
                     evaluated. Monitoring and site characterization
                     guidance and an expert system for permit writers
                     will be developed.

                     Office or                      Total     Percent
                     Laboratory   Contact           Funds ($k)  In-House
                      EMSL/LV    Eugene Meier        733.9       11
                      OMMSQA/HQ KenSala
                                42

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Hazardous Waste
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Quality Assurance

To ensure that the data on which regulations and
enforcement are based are accurate, quality
control (QC) samples will be provided to EPA
contractor, state, and local laboratories conducting
RCRA monitoring. Calibration standards will also
be provided for Appendix IX compounds to EPA
contractor, state, and local laboratories. Natural
matrix, liquid and solid performance evaluation
samples will be developed and distributed to
RCRA contractors, EPA, and state laboratories
conducting RCRA hazardous waste analyses.
Performance evaluation (PE) materials that
contain the pollutants of interest at the levels
encountered in the environment will be developed.
Statistical data on the laboratory evaluations will
be reported to the Office of Solid Waste. Referee
laboratory analyses on all RCRA samples will be
conducted. Traceability to National Institute for
Standards and Technology for Performance
Evaluation (PE), Quality Control (QC), and
method validation study samples prepared for
RCRA monitoring activities will be provided.
                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k)  In-House

                     EMSL/CIN    William Budde      451.0       16
                     EMSL/LV     Eugene Meier       476.3       36
                     AREAL/RTP  William Mitchell     148.8       49
                     OMMSQA/HQ KenSala
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Releases

In order to determine whether underground
storage tanks (UST) containing hazardous wastes
are leaking, evaluation of basic leak detection
monitoring methods for outside an UST will be
conducted. This will include: the establishment of
candidate performance criteria for several classes
of monitoring techniques; the development of test
protocols for determination of the performance
criteria; and testing of the "most promising" leak
detection methods to validate the test procedure
and to establish that instrumentation presently
                               43

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Hazardous Waste
                     exists which can meet the candidate performance
                     criteria.
                       Network design for the placement of leak
                     detection devices will focus on the excavation zone
                     around tanks with emphasis on vapor monitoring.
                     However, monitoring in the saturated zone and in
                     native soils will also be considered.
                       New technologies for leak detection
                     monitoring, such as fiber optics and geochemical
                     sensors, will be evaluated. Methods for monitoring
                     underground storage tanks will be developed and
                     validated, with emphasis on monitoring during
                     bioremediation, soil venting and passive
                     remediation.
                       The Clean Water Act (Section 311) mandates
                     that Spill Prevention Control and
                     Countermeasure plans be prepared for all
                     facilities engaged in the production, storage,
                     processing, and distribution of hazardous
                     materials. The OMMSQA provides remote sensing
                     support to EPA regional offices for SPCC surveys,
                     planning and emergency response activities.
                     Office or
                     Laboratory   Contact

                     EMSL/LV     Eugene Meier
                     OMMSQA/HQ KenSala
                           Total      Percent
                           Funds ($k)  In-House
                            1,444.6
26
Environmental
Engineering
and
Technology
Demonstration
Releases

Underground storage tank (UST) research is
evaluating prevention, detection, and corrective
action technologies to identify cost-effective,
reliable techniques and equipment for USTs.
Early work is producing state-of-the-art
documents for each type of technology. The
primary focus of ongoing work is the evaluation of
leak detection technologies at a test apparatus in
Edison, NJ, and the targeting of high potential
technologies for improved performance. Best
engineering practices for leak prevention, the
detection of leaks, and site cleanup will be
documented.
                               44

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Hazardous Waste
Office or
Laboratory
RREL/CIN
OEETD/HQ

Contact
J. Farlow
R. Nalesnik
Total Percent
Funds ($k) In-House
1,787.9 20
200.0 50
 Environmental
 Processes and
 Effects
Releases

Within this activity, research is conducted to
address evaluation of cleanup techniques for
unplanned releases of hazardous wastes, i.e., the
determination of the applicability and cost-
effectiveness of in-situ reclamation techniques for
unsaturated-zone and ground-water
contamination resulting from leaking
underground storage tanks and other hazardous
waste sources.
  At RSKERL/Ada, coordinated laboratory and
field tests of biological, physical, and chemical
methods, previously tried at hazardous waste
sites, are being conducted to determine their cost
and applicability to cleanup of pollutants from
leaking underground storage tanks.
                     Office or
                     Laboratory  Contact

                     RSKERL/ADA James F. McNabb
                           Total      Percent
                           Funds ($k) In-House
                              93.7
                                        100
 Environmental
 Processes and
 Effects
Waste Characterization

Regulation of hazardous wastes in the most cost-
effective manner requires methods and data for
predicting toxicity of waste materials and
evaluating the concentrations of these materials
at some point of exposure, and then integrating
these methods for different media into single
evaluation techniques which incorporate
uncertainty into the predictions.
  ERL/Duluth is developing procedures and data
to evaluate waste characteristics and closure
criteria for impacts on aquatic habitats and life
forms. Methods are being developed for assessing
effects of waste mixtures and constituents on
aquatic organisms and on habitats. Protocols for
applying these approaches to field sites are being
generated.
                                45

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Hazardous Waste
                        Providing field-evaluated methods and data to
                     predict and remediate the concentrations of
                     hazardous chemicals in the subsurface
                     environment from the treatment, storage, or
                     disposal of wastes is the thrust of the program at
                     RSKERL/Ada. Physical, chemical, and biological
                     processes that govern the transport rate,
                     transformation, and fate of wastes are evaluated
                     and their mechanisms are described in
                     mathematical models. These, in turn, are
                     evaluated through field experiments and their
                     applicability is demonstrated in closure and/or
                     corrective actions at hazardous waste sites.
                        Integrated, multimedia methods and data are
                     being developed by ERL/Athens for implementing
                     waste management decisions and evaluating
                     waste management, treatment, and disposal
                     systems based on potential  human health and
                     environmental impacts. Probabilistic techniques
                     are developed and used to address uncertainty.
                     The various media models are coupled to produce
                     both screening-level and more site-specific
                     multimedia exposure assessment packages.
                        ERL/Corvallis is evaluating the biological
                     hazard associated with contaminated soils,  water,
                     and sediments and is determining the
                     bioavailability (including uptake, translocation,
                     and metabolism) of hazardous chemicals by plants
                     and animals. Multimedia protocols are being
                     tested and field validated in various environ-
                     mental settings at waste and spill sites.

                     Office or                     Total     Percent
                     Laboratory  Contact          Funds ($k) In-House

                     ERL/DUL    Philip M. Cook       691.4       100
                     RSKERL/ADA James F. McNabb   2,4050        58.4
                     ERL/ATH    Rosemarie C. Russo  2,504.2        27.0
                     ERL/COR    Bill A. Williams      254.4        58.7
                     OEPER/HQ   WillC.LaVeille     1,223.8        42.4
                     Waste Characterization
Scientific          This program provides chemical-specific health
Assessment       an^ environmental effects documents to support
                     Resource Conservation and Recovery Act (RCRA)
                     3001 listing decisions. Support is also provided to
                                46

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Hazardous Waste
                     the land disposal restruction program in the form
                     of reference dose documentation. The permitting
                     effort for Treatment, Storage, and Disposal
                     Facilities (TSDF), Office of Solid Waste and
                     Emergency Response (OSWER), is supported by
                     providing technical evaluations and assessments
                     of specific issues that arise in that process. Efforts
                     to refine risk assessment methods and provide risk
                     assessment tools related to hazardous waste are
                     also conducted in this program.
                     Office or
                     Laboratory  Contact
                            Total      Percent
                            Funds ($k)  In-House
                     ECAO/CIN
            Bruce Peirano
2,266
                                        47.0
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Waste Identification

To improve procedures to characterize wastes for
listing under RCRA, research will be conducted to
develop methods for characterizing and detecting
particular wastes and providing criteria for
determining if those wastes constitute a potential
hazard. The lack of standardized methods
emphasizes the immediate need for a
comprehensive program to assure that data of
known quality are being collected. Methods will be
tested for application to highly toxic wastes in soil
and sediments, for detection of organics in the
ambient air of waste disposal facilities, and for
determining the reactions of wastes in all media.
Evaluation and revisions of the analytical
methods contained in the SW-846 document are
being conducted.
  Techniques for field monitoring of waste sites
will be improved, including statistics for sampling
design and for sample handling RCRA land
disposal regulations require the establishment of a
groundwater monitoring program at most
facilities, including detection and compliance of
saturated and vadose zone monitoring. Of
particular importance is subsurface monitoring of
sites and investigation of new techniques for
monitoring soils, and biota, ambient air, and
waste incineration emissions. Methods will be
                                47

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Hazardous Waste
                     developed to detect trace metals in groundwater,
                     ambient water, and sludges.
                       Efforts will be directed toward validating waste
                     incinerator test methods for principle organic
                     hazardous constituents from waste incinerator
                     stacks. Validated methods for continuous
                     monitoring of carbon monoxide and hydrochloric
                     acid emissions from incinerators will be developed.

                     Office or                      Total      Percent
                     Laboratory  Contact           Funds ($k)  In-House

                     EMSL/CIN   William Budde        629.5      57
                     EMSL/LV    Eugene Meier       4,418.6     34
                     AREAL/RTP  William Mitchell       513.6      31
                     OMMSQA/HQ KenSala
                                48

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Toxic Substances
 Environmental
 Processes and
 Effects
Biotechnology

The biotechnology research effort is concerned
with interactions between microorganisms and
ecological processes in an attempt to develop
comprehensive knowledge of the biochemical,
physiological, and genetic mechanisms involved.
The program will examine the potential
environmental risk associated with the
application of genetically engineered
microorganisms (OEMs).
  Assessment of environmental impacts of GEMs
requires reliable methodologies for their
identification and enumeration in environmental
samples. The methods must address the analytical
and operative criteria required for any monitoring
program. They must be sensitive and specific to
differentiate GEMs from the background of
indigenous organisms. They have to be feasible,
accurate, reproducible, and widely applicable
since samples will differ greatly from one another,
such as leaf surfaces and freshwater reservoirs.
  Contained aquatic and terrestrial laboratory
systems (microcosms) are used to assess the fate of
GEMs in various ecosystems. The fate of microbes
in microcosms is compared with fate in natural
systems to assess the validity of laboratory data.
  Research in this area applies techniques of
molecular and classical genetics to ecological
studies to assess survival and growth of novel
microorganisms. Questions of specific niche
requirements, selective advantages of new
genotypes, and potential for causing harmful
effects to  populations, ecosystems, or processes
will be examined. The research also addresses
genetic stability of altered microorganisms,
including transmissibility of plasmids and other
genetic information in situ. All extramural monies
will be expended by the laboratories subsequent to
final planning actions.
                     Office or
                     Laboratory   Contact

                     ERL/GB      Robert Menzer
                     ERL/COR     Thomas Murphy
                     OEPER/HQ   Sam Williams
                            Total      Percent
                            Funds ($k)  In-House
                             224.4
                             260.0
                            2,977.1
100
100
 0
                                49

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Toxic Substances
Environmental
Engineering
and
Technology
Demonstration
Biotechnology/Microbial and Biochemical
Pest Control Agents

This research program plan addresses the three
primary engineering-oriented research concerns
posed by the Office of Toxic Substances (OTS) in
its implementation of the Premanufacturing
Notice (PMN) process of the Toxic Substances
Control Act (TSCA):

• mechanisms of accidental or deliberate release
  of the modified genome or organism from the
  site of production (e.g., in effluents);

• availability and effectiveness of containment
  controls or destruction techniques; and

• worker exposure, particularly due to aerosols.

  In order to satisfy these concerns, the program
is divided into two sub-programs. The first
addresses biologically-based manufacturing
processes; the second addresses deliberate
application to a specific environmental area.
  Data bases are being developed for assisting
with the PMN review under the first sub-program.
These will permit assessment of the occurrence,
magnitude, and degree of risk management
applicable to deliberate and accidental releases
from biologically based manufacturing processes.
Models are being developed along with an
information base which OTS will use as a guide for
identification of potential hazards and
implementation of safeguards for reduction of risk
to acceptable levels.
  Because genetically engineered
microorganisms (GEMs) have already been
developed for applications requiring deliberate
release into the environment, the second sub-
program addresses the development of procedures
for assessing the safety aspects of the engineering
techniques for introducing these microorganisms
into the environment. Information to be developed
will allow an assessment of the risk of migration
from the site and of the management techniques to
prevent or minimize this migration.
                               50

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Toxic  Substances
                       A number of application techniques will be
                     addressed using scenarios appropriate to the
                     environment likely to be encountered.
                     Applications considered for evaluation include:
                     agricultural formulations; pollutant clean-up and
                     control (spills, landfills, contaminated sediments,
                     oil spills); tertiary oil recovery; in-situ mineral
                     recovery (metals leaching, oil shale).
                       The engineering assessment protocols for
                     release and exposure will be structured to account
                     for several sets or combinations of various
                     biological properties, or subsets, and appropriate
                     applications involving deliberate environmental
                     release. Further effort will be devoted to
                     identifying specific data (chemical, physical, and
                     biological) that will be required as inputs to the
                     engineering risk-assessment protocol so that data
                     can specifically be developed and submitted as
                     part of the PMN review procedures.
Office or
Laboratory
RREL/Cin
OEETD/HQ
Contact
John Burckle
Bill McCarthy
                                                 Total     Percent
                                                 Funds ($k) In-House
                                                  520
                                       15
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Biotechnology/Microbial and Biochemical
Pest Control Agents

This research evaluates and standardizes
sampling methodology to identify and quantify
release of microorganisms or biotechnology
products into the environment. Standardized
procedures are developed and used to produce
guidelines to assess human exposure and
environmental impact of Genetically Engineered
Microorganisms (GEMS) release.
                     Office or
                     Laboratory   Contact

                     EMSL/LV     Stephen Hern
                     OMMSQATHQ  Laurie Schuda
                            Total     Percent
                            Funds ($k) In-House
                             238.2
25
                                51

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Toxic Substances
 Environmental
 Processes and
 Effects
Ecology: Ecotoxicity and Risk Assessment

Environmental risk assessment studies on the
linkage of environmental exposure and
ecotoxicology hazard assessment techniques, and
development of methods to evaluate risks
continues. The goal is to be able to predict toxic
risk to varied ecosystems and components within
acceptable limits of uncertainty.
  The ecotoxicology studies include the
movement, transformation and ultimate
disposition of toxic substances in all
environmental media as a critical component of
risk assessment. How plants and animals or
ecosystems and biological interactions are affected
by toxic substances are also the subjects of this
research effort. Research goals include the
identification of important endpoints and
development of mathematical modeling
techniques (population; transport) to integrate
data and depict risk. Input data will include such
results as lab to field comparative  responses,
measurements of ecosystem resistance and
resilience, recovery, population changes
(mortality; feeding behavior), biota uptake and
susceptibility. Techniques such as quotient- based
approaches at various scales of system complexity
and causative factors affecting variations in
toxicity data (taxonomic considerations) and
modeling results will be studied. The validated
predictive tools and the results will be used in
regulatory decision-making and as a guide to
formulating regulatory criteria and standards. All
extramural monies will be expended by
participating laboratories subsequent to final
planning actions.
                     Office or
                     Laboratory   Contact
                     ERL/ATH
                     ERL/COR
                     ERL/DUL
                     ERL/GB
                     OEPER/HQ
                     ERL/NARR
            Rosemarie C. Russo
            Thomas A. Murphy
            Oilman Veith
            Raymond G. Wilhour
            Sam Williams
            Norbert Jaworski
Total
Funds ($k)

 411.7
  84.5
 167.5
   0.0
1,880.2
 112.7
Percent
In-House

  100
  100
  100
    0
   35
  100
                                52

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Toxic Substances
Environmental
Processes and
Effects
Ecology: Transport/Fate/Field Validation

This research encompasses the determination of
the effects, movement, transformation, and
ultimate disposition of toxic substances and their
degradation products that inadvertently enter into
all environmental media. This program provides
information on how plants and animals and larger
ecosystems are affected by exposure to toxic
substances caused by accidents in commerce and
industry. Specific activities include developing
and validating techniques for assessing hazards,
exposure and estimation of the fate of existing
chemicals through lab, microcosm or field studies.
  Information developed in the above studies
provides data necessary for hazard and exposure
assessments and for designing mathematical
models of chemical transport, transformation and
fate including biodegradation. Research addresses
such problem areas as: intermedia transfer,
characteristics of chemicals (e.g., chemical
kinetics/hydrolysis and microbial rate constants)
and the processes of the receiving environment;
comparative toxicological responses; system level
effects (e.g., community alterations); effects of
toxicants on animal and plant development and
applied chemical structure-activity techniques,
methods for measuring ecosystem recovery and
abiotic transformation. Research results help the
Agency to determine potential adverse impacts of
toxicants and to help formulate preventative or
remedial actions.
                     Office or
                     Laboratory   Contact
                     ERL/ATH
                     ERL/GB
                     ERL/COR
           Rosemarie A. Russo
           Robert Menzer
           Thomas A. Murphy
Total
Funds ($k)

 903.8
 733.0
 826.0
Percent
In-House

  100
  100
  100
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Exposure Monitoring

Research for exposure monitoring is dedicated to
development, testing, and standardizing
monitoring methods to estimate total human
exposure and population exposures. Human
                               53

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Toxic  Substances
                     activity patterns are studied to improve estimates
                     of exposure. Human exposure data are used to
                     construct models to estimate an individual's
                     pollutant exposure in all media. Microenviron-
                     ment studies are conducted to fill data gaps.
                     Office or
                     Laboratory
            Contact
                     EMSL/LV    Stephen Hern
                     AREAL/RTP  Dale Pahl
                     OMMSQA/HQ Laurie Schuda
Total
Funds (Sk)

1.175.6
 521.5
 100.0
Percent
In-House

  45
  20
  25
Health Effects
Health: Markers, Dosimetry, and
Extrapolation

This research is aimed at providing techniques to
reduce the uncertainties in risk assessments.
Techniques are needed to extrapolate between
adverse effects seen in animal species and human
health effects and between high doses used in
animal toxicity testing and low doses typical of
environmental exposure. Dosimetry models are
being developed for oral, dermal, and inhalation
routes of exposure. Biological markers research
focuses on the development of indicators of
biological dose and resulting effects for eventual
application to studies of human populations.
                     Office or
                     Laboratory  Contact
                            Total      Percent
                            Funds (Sk) In-House
                     HERL/RTP
                     OHR/HQ
            Elaine Grose
            Randall Bond
4.377.7
            36.7
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Health: Markers, Dosimetry, and
Extrapolation

This research evaluates physiological,
biochemical, genetic and immunologic techniques
as indicators of human exposure to chemical
pollutants. Biomarkers are tested for sensitivity,
selectivity and reliability to indicate episodes of
pollutant exposure.
                                54

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Toxic  Substances
                     Office or
                     Laboratory   Contact

                     EMSL/LV     Stephen Hern
                     OMMSQA/HQ  Laurie Schuda
                            Total      Percent
                            Funds ($k)  In-House
                            322.5
            30
Health Effects
Special Human Data Needs

This research is designed to provide information to
assist in identifying and regulating existing
chemicals with potential human health risks.
Research focuses on developing epidemiological
and biostatistical methods. Efforts in biochemical
epidemiology are underway to identify and
evaluate biomonitoring and screening methods for
potential application to human environmental
epidemiology.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     HERL/RTP
                     OHR/HQ
            Elaine Grose
            Randall Bond
1,541.9
                                                             26.5
 Environmental
 Processes and
 Effects
Structure Activity Relationships

This research is designed to determine the
disposition of new toxic chemicals in all
environmental media and to determine if selected
plants and animals might be affected. This
involves developing structure-activity
relationships (SAR) with methodologies based
upon molecular structure characteristics to
rapidly assess the environmental fate and toxicity
of new chemicals. Structure-activity develops
those data bases and mathematical models which
are used for predicting exposure, bioaccumulation,
toxicity, fate, and other parameters. Activities
include the development of data bases on plant
uptake, fate of organic chemicals, toxicity to fish
and reactivity of chemicals (e.g., photolytic,
electrophilic, nucleophilic). Integrated into this
research is data on transport and transformation
of both organic and inorganic substances in
freshwater and multimedia environments and
application of SAR to predict effects of new
                                55

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Toxic Substances
                    chemicals on biota. The latter includes
                    determination of and predictions on toxic
                    mechanisms and microbial transformation and
                    metabolism. Expert systems are being applied to
                    the SAR approach. Computer based predictive
                    programs are in use in regulatory evaluations.
                     Office or
                     Laboratory   Contact
                     ERL/D6JL
           Rosemarie C. Russo
           Oilman Veith
Total
Funds ($k)

 379.2
 677.4
Percent
In-House

  100
   64
Health Effects
Structure Activity Relationships

Methods are being developed to use combinations
of descriptions based on molecular structure to
predict enzymatic, genetic, carcinogenic, and other
activities of new chemicals to support section 5 of
TSCA. Techniques include pattern recognition
and statistical and thermodynamic analyses. In
addition, chemical data bases are being
constructed for use in predicting toxicological
responses for new chemicals with similar
structures.
                     Office or
                     Laboratory   Contact
                     HERL/RTP
                     OHR/HQ
           Elaine Grose
           Randall Bond
                           Total      Percent
                           Funds ($k)  In-House
1.031.1
  49.5
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Support for Toxic Substances Control Act
(TSCA)

Quality assurance research is conducted to
support routine monitoring and assessment.
Studies are underway to evaluate exposure models
and the use of computer aided technology to
estimate exposure and risk. Reference chemicals
and analytical spectra for chemical compound
identification are produced to provide
                               56

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Toxic Substances
                     standardization procedures and guidelines for
                     program offices field studies.
                     Office or
                     Laboratory   Contact

                     EMSL/CIN    John Winter
                     EMSL/LV     Stephen Hern
                     OMMSQA/HQ Laurie Schuda
                           Total     Percent
                           Funds ($k) In-House
                            346.6
                            365.1
            20
            35
 Scientific
 Assessment
Support for Toxic Substances Control Act
(TSCA)

The scientific assessment program provides
support to the Office of Toxic Substances in the
area of assessments of cancer, mutagenicity,
adverse reproductive/developmental effects, and
exposure. These activities support decision-
making under TSCA (i.e., existing chemicals,
Preliminary Manufacturing Notice (PMN) review,
and test guidelines and test rules development).
                     Office or
                     Laboratory

                     OHEA/HQ
           Contact

           Hugh McKinnon
Total     Percent
Funds ($k) In-House
 377.0
            72.1
 Environmental
 Engineering
 and
 Technology
 Demonstration
Engineering

This program supports the Office of Toxic
Substances (OTS) in its implementation of the
Toxic Substances Control Act (TSCA), Asbestos
Hazard Emergency Response Act (AHERA), and
Title III of the Superfund Amendments and
Reauthorization Act (SARA). The program focuses
on the development of predictive capabilities to be
used in assessing release and exposure levels for
the review of Premanufacturing Notices (PMNs)
for new chemicals, and the techniques and controls
for ensuring "no risk" exposure to existing
chemicals.
   The "new chemicals" sub-program is evaluating
the manufacturing and processing of these
chemicals from both the unit operations and "an
industrial-setting" perspective. Research in the
                               57

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Toxic Substances
                     operations area has focused on drying and
                     filtration equipment. Emphasis has been placed on
                     the frequency of exposure and the magnitude and
                     duration of inhalation and dermal exposure levels
                     in the work place. Additional emphasis has been
                     directed toward simulating the "real-world"
                     environment.
                       Research in the industrial-settings area has
                     been concentrated on those manufacturing
                     scenarios found in the polymer processing
                     industry. Emphasis has been directed toward
                     exposures associated with the off-gassing of
                     monomers, degradation products, and polymer
                     additives.
                       In the fate assessment subprogram, emphasis
                     has been placed on water soluble compounds
                     which ultimately are subjected to secondary
                     wastewater treatment, and in particular,
                     activated sludge  treatment. Based on the high
                     numbers of azo-dye PMN submissions, these dyes
                     remain a priority for investigation.
                       In the past, agency guidance for asbestos in
                     buildings has been developed from the best-
                     engineering judgment concept. Research is
                     continuing to evaluate the effectiveness of current
                     guidance which includes removal, and in
                     situations where the asbestos-containing
                     materials is to be left in place, operations and
                     maintenance procedures.
                       To satisfy the needs of AHERA, efforts will be
                     expanded to evaluate transportation and disposal
                     options, in addition to attempting to indicate the
                     "least-burdensome" strategy when several "risk-
                     free" options are  available. Over the next three
                     years, the program will shift toward developing
                     cost-effective removal/containment technologies
                     and addressing the broader area of controlling all
                     harmful respirable and  durable fibers.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k) In-House

                     RREL/Cin    Roger Wilmoth     2,400        25
                     OEETD/HQ   Bill McCarthy
                                58

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Toxic Substances
 Environmental
 Processes and
 Effects
Test Method Development

To assess environmental hazards, research focuses
on developing, improving and validating single
and multi-species toxicity tests for chronic and
acute toxicity in aquatic ecosystems. The
developed methods support development of testing
guidelines for TSCA and provide basic data for
determining exposure and appropriate endpoints
that can be related to real-world situations.
  Test methods development for aquatic biota
provides new or modified bioassays which support
toxicological evaluations and toxicokinetic models
on such concerns as uptake from contaminated
sediments, extrapolations from species to species
and determining carcinogenic potentials of
chemicals.
                     Office or
                     Laboratory   Contact
                     ERL/DUL
                     ERL/GB
           Gilman Veith
           Robert Menzer
Total
Funds ($k)

 214.6
 231.0
Percent
In-House

  100
  100
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Test Method Development

Test method development research is conducted to
improve procedures to identify and quantitate
chemical compounds of interest. Emphasis is
placed on development of biological and chemical
procedures to measure chemicals in different
media including biological monitoring and
immunochemical procedures. New statistical
techniques are developed for spectra analysis.

Office or                    Total     Percent
Laboratory   Contact          Funds ($k) In-House

EMSL/LV    Stephen Hern       607.2       45
AREAL/RTP  Dale Pahl          200.4       25
OMMSQA/HQ Laurie Schuda
 Health Effects
Test Method Development

Under the Toxic Substances Control Act, EPA
must provide industry with guidance to test
                               59

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Toxic  Substances
                     chemicals for potential hazards to public health. In
                     order to base regulatory decisions on the best
                     possible data, reliable test methods must be
                     developed for incorporation into test guidelines.
                     The goal of this research is to develop short-term,
                     cost-effective, predictive methods for detecting the
                     toxic effects of chemicals. These test systems
                     include both in vitro and in vivo methods and
                     bioassays for predicting adverse health effects
                     such as alterations in reproductive and
                     developmental processes and immunotoxic and
                     neurotoxic effects.
                     Office or
                     Laboratory   Contact
                     HERL/RTP
                     OHR/HQ
           Elaine Grose
           Randall Bond
                           Total      Percent
                           Funds ($k)  In-House
1,771.6
70
 Scientific
 Assessment
Emergency Planning and Community
Right to Know

In support of Superfund Amendments and
Reauthorization Act (SARA) Title III, Section 313,
the scientific assessment program prepares
profiles and incorporates them into the Integrated
Risk Information System (IRIS) to provide
information to various governmental agencies and
the public on the health effects of chemicals
released into the environment.
                     Office or
                     Laboratory

                     OHEA/HQ
           Contact

           Hugh McKmnon
Total      Percent
Funds ($k)  In-House

  50.0        0
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Asbestos

Research is being conducted to develop and
standardize analytical methods for identification
of airborne asbestos fibers in indoor micro-
environments and for sampling and analysis of
floor tiles which may contain asbestos.
                               60

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Toxic Substances
                     Office or                    Total      Percent
                     Laboratory   Contact         Funds ($k)  In-House

                     AREAL/RTP   Dale Pahl           480.6       10
                     OMMSQA/HQ  Michael Dellarco
                     SARA Title III

 Modeling,         Research is conducted to identify methods to
 Monitoring        detect release of chemicals on the SARA Title III
 Sv«itpm s           ^s^ *n^° ^ne environment and to develop human
    A r\   r+        exposure monitoring procedures to assess human
 and Duality       exposure to chemicals released from these
 Assurance        installations.

                     Office or                    Total      Percent
                     Laboratory   Contact         Funds ($k)  In-Mouse

                     EMSL/CIN    John Winter        343.4       20
                     OMMSQA/HQ  Laurie Schuda
                               61

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Pesticides
Environmental
Processes and
Effects
Biotechnology/Microbial and Biochemical
Pest Control Agents

This portion of the research program is planned to
develop or improve bioassay methodologies for
determining the effects of biological control agents
or biochemical agents (e.g., hormones,
pheromones) on non-target biotic receptors. The
application of the methods assists in establishing
testing guidelines and in registering and
controlling the use of these control agents. Agents
of interest include both genetically altered and
unaltered bacteria, viruses and fungi. Parameters
to be studied include routes of exposure, methods
to recover or identify the agents and to estimate
virulence, toxicity and infectivity. Survival,
growth, persistence and effects plus controlling
abiotic factors are of concern.  Generic transfer and
stability associated with genetically engineered
microorganisms (GEMs) will be investigated.
Special handling and monitoring methods and
systems will be studied. Novel control procedures
for pesticide applications using microbial
regulation are being studied. All extramural
monies will be expended by the laboratories
subsequent to final planning actions.
                     Office or
                     Laboratory   Contact
                     ERL/COR
                     ERL/DUL
                     ERL/GB
                     OEPER/HQ
            Thomas A. Murphy
            Oilman Veith
            Robert Menzer
            Sam Williams
Total
Funds ($k)

 189.1
 119.3
 569.9
1,450.0
Percent
In-House

  100
  100
   60
    0
 Health Effects
Biotechnology/Microbial and Biochemical
Pest Control Agents

Models will continue to be developed on potential
interaction of microbial agents and the
mammalian cell. Goals are (1) the determination
of the ability of microbial agents to replicate in
mammalian cells, and (2) to provoke immune
responses in non-target (mammalian) hosts.
Methods will also be developed to identify genetic
material from microbial pesticides in non-target
sites such as mammalian cells in vitro and in vivo.
                                62

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Pesticides
                     Research in this area is also aimed at the
                     development of methods to evaluate the potential
                     health hazards of genetically engineered
                     organisms and the products of these
                     microorganisms. Potential mechanisms of action
                     and screening methods for adverse mechanisms
                     are being investigated. Models are being
                     developed to assess the potential dispersal
                     capability of genetically engineered genes.
                     developed to assess the potential dispersal
                     capability of genetically engineered genes.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     HERL/RTP
                     OHR/HQ
            Elaine Grose
            Randall Bond
1,976.3
28
Environmental
Processes and
Effects
Ecology: Ecotoxicity and Risk Assessment

To register or re-register pesticides it is necessary
to develop a focused risk assessment process for
integrating hazard and exposure assessments to
estimate the probability of risk to important non-
human populations. This facet of the research
program develops environmental risk assessment
methodology by combining impact data using
existing or new models to express risk as a
probability with estimates of the associated
uncertainty.
  New endpoint responses will be studied
encompassing ecosystem structures and function.
Selected wildlife and microbial populations will be
used to reflect population changes and other
changes that influence risk evaluations. Other
parameters that affect model integrity will be
studied (e.g., species susceptibility; chemical
routes of exposure arid uptake and residues).
Modeling will be supported through data
integration and model calibration and validation
will be supported through field studies that
include all media. A pesticide ranking index and
registry system is being developed as a tool for
assessing selected aquatic systems. All
extramural monies will be expended by the
                                63

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Pesticides
                     participating laboratories subsequent to final
                     planning actions.
                     Office or
                     Laboratory   Contact
                     ERL/ATH
                     ERL/COR
                     ERL/DUL
                     ERL/GB
                     OEPER/HQ
            Rosemarie C. Russo
            Thomas A. Murphy
            Oilman Veith
            Raymond G. Wilhour
            Sam Williams
Total
Funds ($k)

   0.0
  50.3
 129.5
   0.0
 780.0
Percent
In-House

    0
   100
   100
    0
    0
Environmental
Processes and
Effects
Ecology: Transport/FatelField Validation

Research will concentrate on the development,
refinement and validation of techniques and
models to measure and predict pesticide transport,
degradation, exposure, effects and fate in the
environment. Laboratory and field studies will be
conducted to substantiate the applicability of
methods and mathematical models and to
determine if results are valid and reflect
environmental responses under natural
conditions. Data from these studies will be used to
assess pesticide hazards to surrogate species,
populations and communities representative of
aquatic (i.e., estuarine) and terrestrial habitats.
  These investigations will include analysis of
abiotic influences on study results and on various
chemical and physical factors and processes.
Sorption, leaching and bioaccumulation will be
evaluated. Ground water contamination and
associated processes will be explored and remedial
actions sought. Information systems will be
developed and used to help implement
management strategies to prevent pesticide
contamination of ground water. Predictive
techniques for exposure assessment technology
will be improved with studies on pesticide sorption
kinetics, transformations, structure reactivity
correlations and mechanisms of degradation.
Terrestrial ecotoxicology studies will include
development of data and methods to assess and
predict stress impacts on wildlife (e.g., bird)
populations including comparability between  lab
and field tests.
   Information and data including assessments
and predictive tools, evaluations of assessment
                                 64

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Pesticides
                     criteria, models and user manuals, workshops and
                     reviews are applied to support the Agency's
                     regulatory actions.
                        All extramural monies will be expended by the
                     laboratories subsequent to final planning actions.
                     Office or
                     Laboratory   Contact
                     ERL/ATH
                     ERL/COR
                     ERL/DUL
                     ERL/GB
                     OEPER/HQ
            Rosemarie C. Russo
            Thomas A. Murphy
            Oilman Veith
            Raymond G. Wilhour
            Sam Williams
Total
Funds ($k)

 539.1
 543.3
 589.5
 986.5
1,398.8
Percent
In-House

   63
   26
   63
   76
   41
 Environmental
 Engineering
 and
 Technology
 Demonstration
Engineering

This program, which supports the Office of
Pesticide Programs (OPP), consists of two major
areas: protective clothing and disposal technology.
Several areas of protective clothing research are
concluding which will provide a "Guidance
Manual for Selecting Protective Clothing for
Agricultural Pesticide Operations." This manual
will serve as a reference document for OPP to use
in protective-clothing issues related to OPP's
regulatory and training activities. This manual
will include standard test methods and
performance data from both laboratory and field
tests. Work on protective clothing is being phased
out.
  OEETD will continue to evaluate existing
disposal techniques and processes for destroying
specific pesticide classes, develop a treatability
database applicable to pesticides and their
disposal, and develop improved container reuse
technology including a test method to ensure
compliance with existing regulations. A major
effort in this area, in conjunction with OPTS, is
evaluation of the effect of "burning" pesticide
bags.
                      Office or
                      Laboratory  Contact
                            Total      Percent
                            Funds ($k) In-House
                      RREL/Cin
                      OEETD/HQ
            Glenn Shaul
            Bill McCarthy
342.9
   60
                                 65

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Pesticides
                    Exposure

                    Research is being conducted to apply the Total
                    Exposure Assessment Methodology (TEAM)
                    approach for measurement of exposure to
                    pesticides residues in children for pesticides used
                    routinely by the general population. Exposure of
                    children to pesticides via personal air, food,
                    drinking water, and dermal exposure in urban
                    enviroments will be studied using TEAM methods.
Modeling,
Monitoring
Systems
and Quality
Assurance
                    Office or                     Total     Percent
                    Laboratory   Contact          Funds ($k) In-House

                    AREAL/RTP   Dale Pahl         201.1        5
                    EMSL/LV     Stephen Hern       158.7        15
                    OMMSQA/HQ  Michael Dellarco
Health Effects
                    Health: Markers, Dosimetry and
                    Extrapolation

                    This research focuses on developing animal
                    models to assess health risks and improve
                    methodology for extrapolating results of animal
                    toxicity studies into risk estimates for humans.
                    Studies include evaluation of interspecies
                    differences in the dermal absorption of pesticides,
                    examination of structure-activity relationships,
                    examination of metabolic differences between
                    species which may contribute to teratogenic
                    outcomes, and the investigation of potential
                    interactions between alterations in maternal
                    health status and susceptibility to pesticide
                    exposures.
                    Office or
                    Laboratory   Contact
                                               Total     Percent
                                               Funds ($k) In-House
                    HERL/RTP
                    OHR/HQ
                               Elaine Grose
                               Randall Bond
1,120.8
56.4
Modeling,
Monitoring
Systems
and Quality
Assurance
                   Health: Markers, Dosimetry and
                   Extrapolation

                   Research is being conducted to relate external
                   dose to internal dose and to identify onset of
                               66

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Pesticides
                     disease states resulting from exposure to pesticide
                     residues. Research studies are being carried out to
                     define the relationship between biological
                     indicators of exposure and dose.
                     Office or
                     Laboratory
            Contact
                     EMSL/LV     Stephen Hern
                     OMMSQA/HQ Michael Dellarco
Total      Percent
Funds ($k)  In-House
                                                  521.4
                                        45
Modeling,
Monitoring
Systems
and Quality
Assurance
Support

The pesticides quality assurance program ensures
the accuracy of the data which is attained through
testing and analysis. The program conducts
quality assurance research and maintains a
Pesticide Repository of high purity chemicals.
Federal and State laboratories use these samples
as standard reference for internal quality control.
Research is conducted to develop procedures to
ensure control in environmental monitoring
studies and analysis of samples for pesticide
residues. Efforts will be initiated in FY90 to  assess
the merits of privatizing the Pesticides Repository.
                     Office or
                     Laboratory   Contact

                     EMSL/CIN    John Winter
                     OMMSQA/HQ Michael Dellarco
                            Total      Percent
                            Funds (Sk)  In-House

                             254.4        0
 Environmental
 Processes and
 Effects
Test Method Development

Laboratory studies will develop, improve and
validate bioassay methodologies to be used as
standardized pesticide testing protocols for aquatic
organisms. Various methods will be geared to
testing chosen life stages of endemic fishes and
crustaceans or surrogate test species for long-term
or short-term durations. These methods will help
assess both exposure and effects (e.g., metabolic,
mortality or teratogenic response) to pesticides
and pesticide ingredients under acute and chronic
conditions and some may be used for monitoring
particular pesticides or sensitive biota and for
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                     predicting response. Influencing environmental
                     factors which may modify testing results will be
                     studied to establish confidence limits for the
                     methods under given conditions. The methods will
                     contribute to establishment of early detection of
                     hazards and provide sensitive, rapid and
                     inexpensive evaluation techniques.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     ERL/GB
            Robert Menzer
 328.2
100
Health Effects
Test Method Development

This research involves developing and refining
bioassays for the detection of adverse alterations
in the development of reproductive processes in
animals which allow for more accurate
evaluations of reproductive development and
function. Techniques are also being developed,
validated, refined and implemented for
determining human genetic effects caused by
exposure to chemicals. Additionally, methods are
being developed to determine the neurotoxicity
and immunotoxicity of pesticides.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     HERL/RTP
                     OHR/HQ
            Elaine Grose
            Randall Bond
2,063.9
73.7
 Scientific
 Assessment
Support for Federal Insecticide, Fungicide
and Rodenticide Act (FIFRA) Activities

The scientific assessment program provides
support to the Office of Pesticide Programs in the
area of assessments of cancer, mutagenicity,
adverse reproductive/ developmental effects, and
exposure. Support is also provided on a case-by-
case basis with laboratory data audits.
                     Office or
                     Laboratory

                     OHEA/HQ
            Contact

            Hugh McKinnon
Total      Percent
Funds ($k)  In-House
 296.5
100
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                     National Health and Nutrition
                     Examination Survey (NHANES-HI)

 Health Effects   The third National Health and Nutrition
                     Examination Survey (NHANES-III) is one of a
                     series of surveys conducted by the National Center
                     for Health Statistics (NCHS) for the purpose of
                     producing vital and health statistics for the
                     United States. Six NHANES studies have been
                     completed since 1960. NHANES-III will be
                     conducted for six years, from 1988-1994. During
                     this time, approximately 40,000 Americans ages 2
                     months and over will be randomly selected from
                     households, interviewed and invited to participate
                     in medical examinations at mobile examination
                     centers. Approximately 30,000 individuals will
                     undergo the medical examination,  which includes
                     a physical examination and diagnostic and
                     biochemical testing. The sample is a statistically
                     representative sample of Americans with
                     oversampling of the very young, the elderly,
                     Blacks and Hispanics.
                        Some of the topics to be studied in NHANES-III
                     are nutrition status monitoring, osteoporosis,
                     arthritis, respiratory and cardiovascular disease,
                     diabetes, gallstone disease, AIDS, kidney disease,
                     and growth and development of children.
                        Research and public health goals include the
                     following: (1) estimating the prevalence of disease
                     and risk factors; (2) estimating the incidence of
                     certain diseases; (3) estimating the prevalence of
                     functional impairment; (4) providing population
                     reference distributions of health characteristics
                     including growth and development; (5) monitoring
                     secular changes in diseases and risk factors; and
                     (6) identifying new risk factors for disease and
                     reasons for secular trends in health.
                        EPA and other Federal agencies have
                     collaborated with NCHS in previous NHANES
                     studies and in NHANES-III. EPA has participated
                     in the planning of NHANES-III and has funded
                     two specific research areas: neurotoxic disorders
                     and pulmonary function.

                     Office or                     Total       Percent
                     Laboratory   Contact           Funds ($k)  In-House

                     OHR/HQ     Susan Perlin       585.0       14.5
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 Health Effects
Center for Environmental Epidemiology
Research

This program responds to a major
recommendation of the EPA Science Advisory
Board which indicated that the agency should
initiate a program of epidemiologic research. The
program is examining the current state of
environmental epidemiology in order to identify
critical areas of research. The initial program
focus is on epidemiologic strategies for the study of
airborne pollutants and their effects on the lung.
                     Office or
                     Laboratory  Contact
                     HERL/RTP
                     OHR/HQ
            Rebecca Calderon
                            Total     Percent
                            Funds ($k) In-House
250.0
 Exploratory
 Research
Exploratory Research Grants

The Research Grants Program supports research
initiated by individual investigators in areas of
priority interest to the Agency. Research proposals
are solicited via two mechanisms: (1) the
"Solicitation for Research Proposals" which is
published each year and invites proposals in
broadly defined areas of environmental science
and engineering, and (2) the Request for
Applications (RFA) which is a more targeted
solicitation mechanism which requests proposals
in well-defined areas of particular interest to the
Agency. All proposals received in response to
either mechanism are subjected to a rigorous peer
panel review. In addition, those responding to the
general solicitation must undergo an Agency
relevance review. Areas in which research
proposals will be requested in FY 1991 under the
general solicitation include: environmental
biology, environmental health, environmental
engineering, environmental chemistry and
physics, and socioeconomics.
  In an effort to provide more support to minority
institutions for the conduct of basic environmental
research, the Research Grants Program makes
available pre-application assistance for minority
faculty at Historically Black Colleges and
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                     Universities through its Minority Institutions
                     Assistance Program. Whether or not this
                     assistance is used, however, research proposals
                     received under this program are reviewed along
                     with proposals received under the general
                     solicitation and in accordance with the standards
                     applied thereunder.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k)  In-House

                     OER/HQ     Roger Cortesi       28,200        0
                     Research to Improve Health Risk
                     Assessment (RIHRA) (Health)

 Health Effects    The Environmental Protection Agency (EPA)
                     relies on quantitative risk assessments of human
                     health effects to guide the regulatory decision-
                     making process in carrying out the mandates
                     given to EPA under existing environmental
                     legislation. The utility of the risk-based decision
                     making process is dependent upon the accuracy of
                     available effects data and on our ability to
                     extrapolate this information to man. In situations
                     where the scientific data are insufficient, the risk
                     manager is presented with a broad range of
                     possible risks upon which to base his decision. This
                     uncertainty has significant impacts and
                     ramifications for the regulatory process in terms of
                     balancing human health risks against other
                     societal needs.
                       The primary objective of the RIRHA program is
                     to develop a systematic and integrated research
                     program to improve the scientific basis supporting
                     health risk assessments. Emphasis is being placed
                     on identifying and addressing the significant
                     uncertainties inherent in the risk assessment
                     process. This program will provide critical
                     information on the relationship between exposure
                     (applied dose), dose to target tissue (delivered
                     dose), and associated health effects. Both
                     laboratory and field research will be conducted
                     that will improve our understanding of basic
                     biological mechanisms, especially as it relates
                     from one set of circumstances to another. Research
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                     will address four major areas: (1) Analysis of
                     Uncertainty in Risk Assessments, (2) Integrated
                     Exposure Assessment, (3) Physiologically Based
                     Pharmacokinetic Models, and (4) Biologically
                     Based Dose-Response Models.
                     Office or                     Total      Percent
                     Laboratory  Contact          Funds ($k)  In-House

                     HERL/RTP   Larry Reiter        7,353.2        3.8
                     OHR/HQ    Ken Sexton
                     Total Human Exposure

 Health Effects    At present, EPA lacks information on human
                     exposure to virtually all chemicals of critical
                     importance to public health. Knowing the number
                     of people exposed and their level of exposure is
                     essential for estimating risk. Without this
                     knowledge, it is currently impossible to make
                     adequate risk assessments, nor can we prioritize
                     the major sources and pathways of exposure. This
                     new long-term program is aimed at developing an
                     exposure data base to serve as a foundation for
                     exposure assessment, and, consequently, risk
                     management strategies.
                       The goal is to measure and predict human
                     exposures and assess trends in human exposure to
                     chemicals of importance to the Agency. Specific
                     objectives include: (1) developing methodologies
                     for exposure measurement and modeling; (2)
                     characterizing representative microenvironments
                     on a national scale; (3) defining regional and
                     nationwide activity patterns; (4) measuring
                     exposure and body burden directly in field studies;
                     (5) determining the major sources of exposure
                     including air, drinking water, and food—and their
                     contribution to risk; (6) developing and validating
                     exposure models and exposure-dose relationships;
                     (7) providing a comprehensive national data base
                     on exposure for use of the Agency and the
                     environmental community; (8) monitoring
                     nationwide trends and regional differences in
                     human exposure and activity patterns, and (9)
                     assessing the effectiveness of regulations by
                     observing these trends in total exposure.
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                        Initially, this program will stress five major
                     areas: (1) measurement methods development for
                     personal monitoring and microenvironmental
                     characterization; (2) chemical characterization of
                     representative microenvironments (air, food, soil,
                     water); (3) documentation of human activity
                     patterns; (4) development and validation of
                     predictive exposure models; and (5) direct
                     measurement of exposure to validate models.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k)  In-House
                     AREAL/RTP  Gerald Akland      2,400.0       30
                     EMSL/LV     Gareth Pearson     1,000.0       12
                     EMSL/CIN    AlDufour           225.0        0
                     OMMSQA/HQ  Chris Saint
                     OHR/Hq      Thomas Miller
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Ecological Trends

This program will identify, collect, organize, and
analyze environmental monitoring data and
report periodically to the Administrator,
Congress, and the public on the current status and
trends in indicators of the condition of the nation's
ecological resources. This will allow EPA to better
assess the status and extent of current
environmental problems, by providing diagnostic
clues as to the cause of these problems, by
establishing baseline conditions against which
future change can be measured, and by assessing
the degree to which regulatory programs, singly or
together, protect the nation's ecological resources.
The Environmental Monitoring Assessment
Program (EMAP) will focus on regional- and
national-scale problems and will target program
outputs at EPA officials who must respond to
Congress and the public and senior managers who
must direct EPA's finite resources where they will
be most beneficial.
   Scientifically, EMAP will: (1) identify,
characterize, classify, and quantify the ecological
resources at risk; (2) design statistical sampling
frames that provide unbiased estimates of
environmental conditions on a regional basis; (3)
identify, evaluate, and develop indicators of
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                     ecological condition; (4) develop operational
                     monitoring programs at a national level for
                     resources of greatest concern; and (5) develop data
                     management and quality assurance systems that
                     allow timely analysis and periodic reporting of
                     program results.
                     Office or
                     Laboratory  Contact
                            Total
                            Funds ($k)
EMSIVCIN
ERL/COR
ERL/DUL
ERL/GB
EMS1VLV
ERIVNARR
OEPER/HQ
OMMSQA/HQ
AREAIVRTP
Bob Graves
DanMcKenzie
Steve Hedtke
Kevin Sommers
Bruce Jones
John Paul
Courtney Riordan
Rick Linthurst
Jay Messer
364.1
6,795.7
364.1
3,724.1
5,833.5
3,874.9
500.0
4,725.2
1,354.5
Percent
In-House

  27.9
   6.0
  27.9
   2.7
  10.5
   7,9
   0.0
  10.4
  22.5
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Reducing Uncertainty in Ecological Risk
Assessment

The goal of the program is to model the expected
response of representative estuaries in the region
in response to alternative risk management
options as an example of a systems level approach
to ecological risk assessment,
  In order to evaluate the uncertainty associated
with the temporal variability  in indicators of
ecosystems condition, a field study is being
undertaken in the estuarine resources of a mid-
Atlantic prototype region. This activity will be
conducted in cooperation with the ecological status
and trends program (EMAP) and NOAA, and will
target exposure and condition indicators and their
response to changing pollutant levels. Ancillary
data needed to run and evaluate the transport and
effects models that will be applied to status and
trends data is also being collected as part of this
effort. Analyses of the data from the first year of
field data from the prototype region will seek
correlations among indicators that could identify
possible causes of poor  condition and will report
the condition of estuaries in the prototype region.
An effort to develop a risk characterization
framework for assessing exposure and effects is
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                     currently underway. Sensitivity analyses are
                     being performed and new multi-variate
                     techniques are being developed that will reduce
                     uncertainty in detecting regional changes and
                     better evaluate effects models that can be used in
                     ecological risk assessment.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k)  In-House

                     ERL/NARR   John Paul         3,000         0
                     OMMSQA/HQ  Chris Saint
                     Exploratory Research Centers

Exploratory      The purpose of the Exploratory Research Centers
Research          Program is to provide dedicated support over
                     several years to fundamental, multidisciplinary
                     research in topics of interest to the environmental
                     community. The first solicitation in 1980 resulted
                     in eight such research centers. These centers were
                     established between 1980 and 1981 and have
                     operated continuously since then. The eight
                     original centers are currently being phased out. A
                     solicitation to establish four new centers funded at
                     $1.0 million per year, was published in the spring
                     of 1990. The new centers should be in place by
                     June 1991. Scheduled funding of the centers
                     terminates in 1991 and 1992.
                       The centers which are currently operating are
                     listed below:
                       Industrial Waste Elimination Center (Illinois
                     Institute of Technology)—studies innovative
                     technology and process modification to reduce
                     industrial pollutants
                       Intermedia Transport Research Center
                     (University of California at Los Angeles)—defines
                     chemical and physical processes governing
                     pollutant exchange at air-land and air-water
                     boundaries
                       Ecosystems Research Center (Cornell
                     University)—identifies and applies ecosystem
                     principles to environmental management
                     problems
                       Marine Sciences Research Center (University of
                     Rhode Island)—assesses marine ecosystems
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                     health, emphasizing exposure of marine
                     organisms to toxics
                       Advanced Control Technology Research Center
                     (University of Illinois)—studies separation
                     technology, thermal destruction, biological
                     separation, and chemical detoxification
                       Ground Water Research Center (Rice
                     University, Oklahoma State University, and the
                     University of Oklahoma)—studies subsurface
                     characterization, transport and fate, and ground
                     water horizon modeling
                       Environmental Epidemiology Research Center
                     (University of Pittsburgh)—studies basic
                     epidemiology methods and airborne particulate
                     health effects studies
                       Hazardous Waste Research Center (Louisiana
                     State University)—conducts research to develop
                     advanced technologies for the destruction,
                     detoxification, recovery, or containment of
                     hazardous wastes
                     Office or
                     Laboratory

                     OER/HQ
            Contact

            Roger Cortesi
Total      Percent
Funds ($k)  In-House

4,600         0
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
National Institute of Ecological Research

As part of its report titled "Future Risk: Research
Strategies for the 1990's", the EPA's Science
Advisory Board (SAB) recommended that:
  "EPA should provide Federal leadership for a
national program of ecological research by
establishing and funding an Environmental
Research Institute."
  EPA has responded to this recommendation by
initiating planning for a National Institute of
Ecological Research. The goals of the Institute are
to monitor, understand, and predict ecosystem
response to anthropogenically induced stress. The
level of effort needed to reach these goals will
require more funds than EPA alone is likely to be
able to provide. The structure of the Institute
provides a mechanism for leveraging and/or
acquiring support from both the private sector and
other Federal agencies.
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                       The planning for a national institute of
                     ecological sciences will assess appropriate
                     mechanisms for implementing and operating an
                     institute. A number of implementation options
                     will be developed based on the outcome of a series
                     of public meetings and hearings and input from
                     several prominent universities. A group of leading
                     scientists will be selected to evaluate these options
                     in terms of their feasibility, chance of success, and
                     their potential to improve the state of science.

                     Office or                     Total      Percent
                     Laboratory   Contact          Funds ($k)  In-House

                     OMMSQA/HQ  Rick Lmthurst       600.0       0
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Environmental
Processes and
Effects
China Program

This research program, which is conducted under
the 1980 US-PRC Environmental Protection
Protocol, studies the relationship of lung cancer
and indoor coal smoke pollution in a rural setting.
The program will begin to shift its focus to a study
of children's respiratory health across a wide
gradient of particulate, acid, and sulfur oxide
exposures in several Chinese cities. The focus in
1991 is on performing a full-scale study in Xuan-
Wei to determine levels of indoor pollution
exposure to compare to the broadly varying
observed lung cancer rates there. In addition, a
pilot study is beginning as part of a five-year
multi-city study of lung function and respiratory
health in children. The full scale study will likely
begin  in 1991 as well. In addition, there is
research underway on environmental processes
and effects of pollution on aquatic organisms,
ground water and water pollution fate and
transport models.
                     Office or
                     Laboratory

                     AREAL/RTP
                     ERL/ADA
                     ERL/ATH
                     ERL/DUL
                     HERL/RTP
                     OEPER/HQS
            Contact

            William Wilson
            Lowell Leach
            Rosemarie Russo
            Nelson Thomas
            Robert Chapman
            Chieh Wu
Total
Funds ($k)

 208.4
 124.0
 247.0
 154.0
 305.1
Percent
In-House

    0
    83
    56
    56
    44
 Health Effects
Task Force on Environmental Cancer and
Heart and Lung Disease

The Task Force is evaluating the link between
environmental factors and human diseases.
Research recommendations are being provided by
the Task Force to involved agencies based upon
research needs identified by scientists who
participate in workshops on topics that are
selected by the Task Force. A report is being
prepared on Environmental Health Risk
Education and a workshop is being held on
environmental exposure data bases.
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                     Office or
                     Laboratory   Contact
                     HERL/RTP
                     OHR/HQ
            Tom Miller
                            Total     Percent
                            Funds ($k) In-House
 300.0
 Health Effects
Harvard Study

This research program identifies and selects post-
doctoral research fellows and visiting scientists to
work with Harvard faculty members on research
projects that address critical environmental
problems that face society.
                     Office or
                     Laboratory

                     HERL/RTP
                     OHR/HQ
            Contact
            Randy Bond
Total      Percent
Funds ($k)  In-House
 250.0
 Scientific
 Assessment
Consistent Risk Assessment

The scientific assessment program provides
uniform Agency-wide guidance on, and assures
the consistency of, exposure and risk assessments
that support regulatory decision making by EPA.
  The program consists of three major
components—Risk Assessment Guidelines, the
Risk Assessment Forum, and the Integrated Risk
Information System.
  Risk Assessment Guidelines—Work will
continue on the development of Agency-wide
assessment guidelines. Proposed guidelines on
exposure and health effects will be issued as final
guidance. Efforts are also being devoted to
development of new guidance related to
pharmacokinetics and ecotoxicity.
  Risk Assessment Forum—The Risk Assessment
Forum, a group of senior scientists, meets
regularly to promote consensus on risk assessment
issues and to ensure that this consensus is
incorporated into appropriate risk assessment
guidance.
  Integrated Risk Information System (IRIS)—
EPA's Integrated Risk Information System (IRIS)
is an electronic data base of summary health risk
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                     information and regulatory information on
                     chemical substances. Primarily intended to serve
                     as a guide for EPA staff when assessing the health
                     risk posed by a chemical, IRIS is available to EPA
                     contractors, state and international
                     environmental agencies, other federal agencies,
                     universities and other risk assessors. The risk
                     information on IRIS represents consensus Agency
                     position on  the potential adverse human health
                     effects of the chemical on-line. Health information
                     on additional chemicals is constantly added to
                     IRIS as it is reviewed and agreed upon by EPA
                     review groups of expert scientists. Included in the
                     data base are some Superfund Amendments and
                     Reauthorization Act (SARA) Title III right-to-
                     know chemicals.
                     Office or
                     Laboratory

                     OHEA/HQ
           Contact

           William Farland
Total      Percent
Funds ($k)  In-House
4,557.6
            59.6
 Technology
 Transfer,
 Regulatory
 Support and
 Regional
 Operations
 Activities
Manage ORD's Technology Transfer,
Regulatory Support and Regional
Operations Activities

The Office of Technology Transfer and Regulatory
Support (OTTRS) has three outreach activities:
ORD's participation in the Agency's regulatory
development process to ensure its scientific
defensibility; a comprehensive and systematic
ORD technology transfer effort with emphasis on
state and local governments and industry; and
more effective assistance by ORD to EPA Regional
Offices. The Director advises the Assistant
Administrator on the priority science-policy issues
and the regulatory support provided directly to
Program Offices by ORD scientists and engineers.
OTTRS also oversees the establishment and
improvement of ORD program effectiveness
through technology transfer and ORD-specific
implementation of the 1986 Federal Technology
Transfer Act. OTTRS promotes Regional Research
needs in the planning process.
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                     Office or
                     Laboratory   Contact
                     OTTRS
            Peter Preuss
Total      Percent
Funds ($k)  In-House

12,014
 Modeling,
 Monitoring
 Systems and
 Quality
 Assurance
Manage the Mandatory Quality Assurance
Program

Each year, EPA devotes more than $500 million to
environmental data operations. Quality
Assurance (QA) activities play an integral role in
the planning and implementation of these
operations, and in the evaluation of the resulting
data. By means of their QA programs, EPA
organizations can enjoy substantial resource
savings, because they collect only those data that
are needed, and because they can be sure that the
data they collect are appropriate for their intended
use.
   Quality assurance is the process of
management review and oversight at the
planning, implementation, and completion stages
of an environmental data collection activity to
assure that data provided by a line operation to
data users are of the quality needed and claimed.
Quality assurance should not be confused with
quality control (QC); QC includes those technical
activities required during data collection to
produce the desired data quality and to document
the quality of the resulting data (e.g., analysis of
sample spikes and blanks).
   Quality assurance programs consist of specific
activities conducted before, during and after
environmental data collection. During the
planning of an environmental data collection
program, QA activities focus on assuring that the
quality of the data needed by data users has been
defined by the data user/decision maker,
communicated to the technical staff, and that a QC
system has been designed to result in the
production of the appropriate data quality, and to
facilitate its measurement and documentation.
During the implementation of a data collection
effort, QA activities ensure that the QC system is
operating as intended and that problems found by
QC are corrected. After environmental data are
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                     collected, QA activities focus on assessing the
                     quality of the resulting data. Here, one determines
                     whether the quality, quantity, and kind of data
                     obtained are adequate to support data-dependent
                     regulatory decisions or research hypotheses.
                        The Quality Assurance Management Staff
                     (QAMS) is charged with overseeing the quality
                     assurance activities of the Agency. QAMS came
                     into being in May 1979, when the Agency
                     recognized the need for formalizing an Agency-
                     wide quality assurance program for all
                     environmental data collection activities. More
                     recently, with the issuance EPA Order 5360.1 in
                     April 1984, the Agency's quality assurance
                     program has been significantly strengthened and
                     broadened. The Order mandates that QA be an
                     integral part of all environmental data collection
                     activities, from planning through implementation
                     and review.
                        The Order identifies the activities basic to the
                     implementation of a QA program. These include:

                     •  requiring QA in all Agency-supported
                        environmental data collection activities,

                     •  defining Data Quality Objectives,
                     •  developing quality assurance program and
                        projects plans,
                     •  conducting management and technical audits
                        and reviews,
                     •  implementing corrective actions based on the
                        findings/recommendations of audits,
                     •  establishing achievable data quality limits for
                        methods cited in EPA regulations,
                     •  developing and adopting technical guidelines
                        for assessing data quality, and
                     •  providing for QA training.

                        In recent years, the Agency's QA activities have
                     focused on identifying the basic elements that are
                     essential to effective quality assurance for
                     environmental data. QAMS has put considerable
                     emphasis on issuing guidance defining these key
                     elements and describing their importance in the
                     efficient and effective expenditure of resources
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                     assigned to environmental data collection. This
                     guidance development phase has now been
                     completed, and in FY 1991 QAMS will continue
                     with full-scale implementation support and
                     oversight.
                     Office or
                     Laboratory  Contact

                     OMMSQA/HQ Nancy Wentworth
                           Total      Percent
                           Funds ($k)  In-House
                            1,785.8
            53
 Exploratory
 Research
Visiting Scientists Program

The Visiting Scientists Program has two
components: a competitive visiting scientists and
engineers program and a summer fellowship
program. The objective of the Visiting Scientists
and Engineers Program  is to attract accomplished
visitors into the Agency for 1 to 3 years to assist in
strengthening the Agency's science policy and
research program. Candidates are sought through
annual advertisements in nationally known
scientific and engineering publications. They are
then subjected to a rigorous peer review from
which only the top candidates are recommended
for assignment to an EPA laboratory. In FY 1990
five candidates passed peer review.
  The Summer Fellows  Program is carried out in
cooperation with the American Association for the
Advancement of Science and sponsors the
assignment of post-doctoral and mid-career
environmental science and engineering fellows to
EPA facilities for the summer months to conduct
environmental research projects. In FY 1990, 10
highly qualified fellows were sponsored.
                     Office or
                     Laboratory   Contact
                     OER/HQ
            Roger Cortesi
Total      Percent
Funds ($k)  In-House

 195         0
 Exploratory
 Research
Small Business Innovation Research
(SBIR) Program

Public Law 97-219 requires EPA to devote 1.25%
of its extramural research and development
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                     budget to Small Business Innovation Research
                     (SBIR). The SBIR Program funds, via contracts,
                     small businesses with ideas relevant to EPA's
                     mission. The program focuses exclusively on
                     projects in control technology or process
                     instrumentation development. Proposals are
                     solicited in the fall of each year for Phase I
                     research. Phase  I research consists of feasibility
                     studies which are supported at a level of up to
                     $50,000. Of these Phase I studies, the best are
                     selected for Phase II studies where actual product
                     development is started. Phase II studies are
                     supported up to a level of $150,000. To date, half of
                     the Phase I efforts have been supported in Phase
                     II. Results from the SBIR Program are expected to
                     lead to the commercial development of a product or
                     process used in pollution control.
                     Office or
                     Laboratory  Contact

                     OER/HQ     Donald Carey
                            Total
                            Funds ($k)

                            3,100
Percent
In-House
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Development, Validation and
Standardization of Analytical Methods in
Support of Regional Programs

This research is targeted at specific areas that
have been identified as regional analytical support
needs. The intention is to work closely with the
regions in order to set priorities within and among
these target areas. Based on our current
understanding of regional needs, a work plan will
be developed and research will be initiated in the
following high priority areas:  1) low level methods
and reference materials for nutrients, volatile and
semi-volatile organics, and metals in all media, 2)
digestion techniques for metals, 3) analysis of
transition metals in non-aqueous media, 4) solid
phase extraction sample preparation techniques
for extractable compounds, and 5) validated
methods for fish tissue and nutrients in marine
systems ecological trends.
                                84

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Multimedia
                   Office or                    Total      Percent
                   Laboratory   Contact         Funds ($k)  In-House

                   OMMSQA/HQ Jack Puzak         975.0       0
                   OMMSQA/HQ Chris Saint
                             85

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Energy
Environmental
Engineering
and
Technology
Demonstration
Develop and Evaluate LIMB Technology

This area is supporting the evaluation of
alternative acid rain control technologies:
specifically the development and
commercialization of an integrated NOX/SO2
control technology—The Limestone Injection
Multistage Burner (LIMB).
  LIMB technology can substantially reduce both
NOX and SC>2 emissions while at the same time
reducing the costs for control. A systematic
development and demonstration program is
underway to bring LIMB technology to the point
where industry is able to commercialize it. The
program has completed a successful wall-fired
boiler demonstration at Ohio Edison's Edgewater
Station. SO2 emissions were reduced by 50-70%
dependent on operating mode and NOX was
reduced below 0.5 Ibs.  NO2/million BTU. The FY
1991 program will include: research to further
optimize sorbent performance; analysis to identify
potential operability and reliability problems; and
construction and installation of LIMB equipment
for the EPA/industry cofunded 180 MWe
demonstration on a tangentially coal-fired utility
boiler.
                     Office or
                     Laboratory   Contact
                     AEERL/RTP
                     OEETD/HQ
           Mike Maxwell
           Marshall Dick
Total
Funds ($k)

3,336.6
 193.9
Percent
In-House

  30
  77
 Modeling,
 Monitoring
 Systems and
 Quality
 Assurance
Understanding Atmospheric Processes

Development will be continued on atmospheric
deposition models used for interpreting and
forecasting effects. In particular, the state-of-
science Regional Acid Deposition Model (RADM)
will continue to be field evaluated and
documented, then applied to policy and program
design questions, monitoring network design and
trends analysis, and interprogram effects issues.
The RADM model will also be applied to U.S. -
Canadian transboundary flux issues, residual
                               86

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Energy
                     NAPAP assessment questions, and the Clean Air
                     Act implementation.
                     Office or
                     Laboratory

                     AREAL/RTP
            Contact

            Jim Vickery
Total      Percent
Funds ($k)  In-House

3,515.9         5
 Modeling,
 Monitoring
 Systems and
 Quality
 Assurance
Establish Deposition Monitoring and
Trends

This research will focus on obtaining data and
analyzing trends for ion levels in wet and dry
deposition to form a composite of total deposition
on both a national and a sensitive regional scale.
Existing networks will be supported and
maintained (200 wet sites and 50 dry sites), with
siting criteria undergoing statistical development
to optimize and enhance both wet and dry research
networks. Instrumentation and methods
development, quality assurance, and a central
data repository - Acid Deposition System (ADS)
are integral parts of this program. The high
quality data provided will be used to plan and
judge the success of the U.S. and Canadian control
strategies.
                     Office or
                     Laboratory

                     AREAL/RTP
            Contact

            Jim Vickery
Total      Percent
Funds ($k)  In-House

3,615.9         5
                               87

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Radiation
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Off-Site Monitoring Program

The overall goal of the research program is to
provide the scientifically credible data necessary
to assess public exposure to non-ionizing radiation
and to man-made radioactive materials and to
allow decisions to be made regarding control of
that exposure.
  In addition, this program provides quality
assurance for the Agency's programs for
monitoring radiation in the environment. These
are supported by providing a common source of
radionuclide standards and reference materials,
and through laboratory intercomparison studies
conducted to assure data of known quality from
analyses of environmental samples such as milk,
water, air and food.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k)  In-House
                     EMSL/LV
                     OMMSQA/HQ
            Charles Costa
            William Keith
289.4
           100
 Environmental
 Engineering
 and
 Technology
 Demonstration
Scientific Support for Radon Program

This engineering program for Radon Mitigation
supports the Agency's Radon Action Program. It is
directed at developing and demonstrating cost-
effective methods for reducing radon to less than 1
pCi/L in houses, schools, and other structures. The
results of these tests, along with analysis of the
findings of others, are provided to the States,
private sector organizations (such as builders and
contractors), and to homeowners.  The research
will continue to extend the capability of existing
radon mitigation to achieve near-ambient radon
levels. In addition, new innovative techniques will
be developed to cost-effectively reduce low-radon-
level houses (responsible for 85% of the risk) to
even lower levels. The research focuses on radon
mitigation techniques for existing houses,
prevention techniques for new construction, and
mitigation techniques applicable to school
buildings.
                               88

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Radiation
Office or              Laboratory  Contact         Funds ($k) In-House

                    AEERL/RTP  Michael Osborne    3,457.8      32
                    OEETD/HQ  Marshall Dick       192.8      78
                              89

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Superfund
Modeling,
Monitoring
Systems
and Quality
Assurance
Provide Techniques and Procedures for
Site and Situation Assessment

Analytical protocols, sampling techniques,
monitoring methods, and data interpretation
approaches useful for characterizing air, surface
and ground water, wastes, and soils at Superfund
sites will be developed, evaluated, and
demonstrated. These methods include air
monitoring techniques, sample collection
procedures, geophysical methods; x-ray
fluorescence measurements of metal
concentrations; remote sensing techniques and
geographic information systems for collection and
analysis of present and historical site data; soil
core preparation procedures; portable gas
chromatography for volatiles analysis; personal
computer-based geostatistics computer programs;
and hydraulic properties of soils.

Office or                    Total     Percent
Laboratory  Contact          Funds (Sk)  In-House

EMSL/CIN   William Budde      558.1       50
AREAL/RTP  William Mitchell     375.3       25
EMSL/LV    Michael Hiatt      2,018.7       40
OMMSQA/HQ Michael Dellarco
Scientific
Assessment
Provide Techniques and Procedures for
Site and Situation Assessment

Site-, chemical- and situation-specific exposure
and risk assessments are being prepared to assist
the Program Office and Regions in evaluating the
alternative courses of action and regulatory
strategies that might be applied at uncontrolled
Superfund sites through development of health
and environmental effects assessments for the
chemicals most frequently found at candidate
sites. The office is also a major participant in the
lead demonstration project in several cities.
                     Office or
                     Laboratory   Contact
                           Total      Percent
                           Funds ($k)  In-House
                     ECAO/CIN
           Bruce Peirano
                                                 548
                                                            5.0
                               90

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Superfund
Environmental
Engineering
and
Technology
Demonstration
Clean-up of Uncontrolled Hazardous
Waste Sites Requires Technologies for
Response and Remedial Action, for
Protecting the Personnel Involved and for
Supporting Enforcement Actions

This research program develops and evaluates
clean-up technology, demonstrating proto-type
equipment such as mobile thermal treatment and
mobile soil washing systems. Remedial technology
will be assessed and technical reports provided
which will include design data and cost
information. Engineering expertise will be applied
to the assessment of uncontrolled hazardous waste
site situations to assist the Office of Emergency
and Remedial Response, Regions and others in the
development of corrective measure options. In
order to provide more effective long-term technical
support to the Regional Offices making cleanup
decisions, the Superfund Technical Assistance
Response Team (START) program has been
established. In addition, short-term, quick turn-
around technical programs and consultation will
be provided to the regional programs and the
Office of Waste Programs Enforcement for
enforcement support.
  The Superfund  Innovative Technology
Evaluation (SITE) program has been established
to enhance the development and demonstration,
and thereby establish the commercial availability
of innovative technologies as alternatives to
containment systems. The primary goal of the
SITE program is to evaluate these technologies on
Superfund materials in order to develop reliable
cost and performance data.
                    Office or
                    Laboratory   Contact
                    RREL/CIN
                    OEETD/HQ
           R. Olexsey
           S.James
           B. Blaney
           R. Nalesnik
Total     Percent
Funds ($k) In-House

30,200       9
 1,500.0
                                      75
                              91

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Superfund
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Provide Quality Assurance—Superfund
Program Requirements

Effective remedial actions at Superfund sites
depend upon analytical data of appropriate
quality. This program provides support to the
Office of Emergency and Remedial Response's
Contract Laboratory Program (CLP), which is
responsible for most contract chemical analyses
under the Superfund program. Support is provided
to the CLP in numerous ways. Quality  assurance
reference materials, such as calibration standards,
quality control samples, and performance
evaluation samples are prepared, and distributed
according to uniform and consistent protocols for
analysis by contract laboratories. The analytical
data generated by the laboratories are  audited in
order to assess intra- and inter-laboratory
performance and method performance. These data
are maintained in the Quality Assurance/Quality
Control Data Base. On-site contract laboratory
inspections are performed to complement the
performance evaluations. Based on method
performance data, existing analytical protocols
are reviewed and improved. A quick response
referee laboratory service is provided for use of the
EPA Regions.

Office or                    Total      Percent
Laboratory  Contact          Funds ($k)  In-House

EMSL/CIN   William Budde     1,261.6       15
EMSL/LV    Michael Hiatt      2,428.5       25
OMMSQATHQ Michael Dellarco
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Provide Technical Support to
Enforcement, Program, and Regions

Site specific monitoring and characterization for
all media in support of Superfund investigations is
provided to the Agency as part of the Technical
Support Program. Monitoring and
characterization support activities are provided on
an as-requested basis. These include: remote
sensing for historical and current site assessment;
air, water, ground-water, and soils monitoring for
site characterization; and analytical chemistry
                               92

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Superfund
                     support. Advice and technical assistance on
                     sampling methods, design of sampling plans, and
                     sample analysis is provided. The full range of
                     quality assurance/quality control assistance is
                     offered including design and review of quality
                     assurance plans, provision of quality control
                     materials, and data analysis and interpretation.

                     Office or                     Total      Percent
                     Laboratory   Contact           Funds ($k)  In-House

                     EMSL/CIN    William Budde       308.0       30
                     AREAL/RTP   William Mitchell     309.0       25
                     EMSL/LV     Michael Hiatt       974.1       25
                     OMMSQA/HQ  Michael Dellarco
 Environmental
 Processes and
 Effects
Provide Technical Support to
Enforcement, Program and Regions

This function provides rapid technical expertise
and services to the Office of Waste Programs
Enforcement, the Office of Emergency and
Remedial Response, Regional Offices, the
Environmental Response Team, Department of
Justice, and state governments.
   Laboratory personnel and facilities are
available on a "when and where requested" basis
to provide site- and case-specific technical support.
Assistance includes training or advice on use of
sampling and analytical techniques and on use of
appropriate assessment models, including those
for ecological risk estimation. In addition,
Technical Support Centers for information on
remedial action technologies, methods, case
histories, etc., will be continued. Bioassessment
assistance will focus on evaluation and application
of protocols to leachate and contaminated soil
samples and performing environmental assays.
Technical support will also be provided on
contaminated marine coastal areas and on
polluted sediment remediation. A multimedia,
human exposure/risk assessment methodology for
prioritizing candidate remedial action sites in
terms of their threats to human health will be
developed and applied.
                                93

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Superfund
                     Office or
                     Laboratory   Contact

                     RSKERL/ADA M. Richard Scalf
                     ERL/ATH
                     ERL/COR
                     ERL/NARR
                     ERL/DUL
                     ERL/GB
           Rosemarie C. Russo
           Bill A. Williams
           Norbert A. Jaworski
           Douglas W. Kuehl
           Raymond Wilhour
Total
Funds ($k)

1,500.4
 877.2
 549.1
 348.1
 104.6
 105.6
Percent
In-House

  37.7
  36.6
  13.1
  30.7
   0.0
  65.2
 Scientific
 Assessment
Provide Technical Support to
Enforcement, Program and Regional
Offices

Site- and chemical-specific health assessments are
being provided to support the needs of the
Program Office, Enforcement Office and Regions
for remedial planning and cost recovery efforts.
Assessments provided range from brief hazard
summaries to detailed and peer-reviewed
documents used in negotiations and litigation.
  Risk assessments developed by Regional Offices
are reviewed for consistency, technical quality,
and adherence to Agency risk assessment
guidelines. Technical support is provided to the
States and Regions through a Technical Support
Center for Health and Risk Assessment, for rapid
turnaround of risk assessment information and
other activities.
                     Office or
                     Laboratory   Contact
                           Total      Percent
                           Funds ($k)  In-House
                     OHEA/HQ
                     ECAO/CIN
            Kevin Garrahan
            Pei-Feng Hurst
10,226
  61.0
 Modeling,
 Monitoring
 Systems
 and Quality
 Assurance
Hazardous Substance Health, Risk and
Detection

Section 311c of the Superfund Amendments and
Reauthorization Act authorizes EPA to conduct
research "with respect to.. . detection of hazardous
substances in the environment." The purpose of
this program is to develop and evaluate
monitoring techniques and systems which are
rapid and inexpensive, fill technical voids,
                               94

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Superfund
                     integrate monitoring systems into multimedia site
                     assessments, and are as specific, selective and
                     sensitive as possible. Innovative approaches which
                     offer potentially significant cost and time savings
                     to Superfund site investigations are studied. These
                     include: development of improved statistical
                     sampling designs, development of improved
                     techniques for managing and interpreting field
                     data, and development of screening techniques
                     such as immunoassay and chemical sensors.
                     Office or
                     Laboratory   Contact
                            Total     Percent
                            Funds ($k) In-House
                     EMSL/LV
                     OMMSQA/HQ
            Michael Hiatt
            Michael Dellarco
1,853.3
                                                             15
 Scientific
 Assessment
Hazardous Substances Health Effects/Risk
Assessment and Detection Research

This program fulfills, in part, the Agency's
responsibilities under the new Section 311(c) to
establish a research program to assess, detect, and
evaluate effects on, and risk to, human health
from hazardous substances. It enhances the
Agency's internal research capabilities relative to
Comprehensive Environmental Response,
Compensation, and Liability Act (CERCLA)
assessment activities. The scientific assessment
research program, specifically, is integrated with
the health effects program, and is developing data
and procedures to fill information and assessment
gaps that exist in the various phases of the
Superfund public health evaluation process, e.g.,
toxicity assessment, risk characterization, and
exposure assessment. Test methods are being
developed to allow evaluation of the hazard
potential of waste mixtures and to assess complex
exposure. Screening techniques for early detection
of adverse health effects are being developed as
are improved measurement techniques for non-
cancer health endpoints such as reproductive
effects. Extensive programs in pharmacokinetic
modeling and exposure assessment methodology
development are also underway.
                                95

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Superfund
                     Office or
                     Laboratory

                     OHEA/HQ
           Contact

           Michael Callahan
Total      Percent
Funds ($k)  In-House
2,169
8.0
Health Effects
Hazardous Substances Health Effects/Risk
Assessment and Detection Research

Research develops data and methods to improve
the Superfund human health evaluation process,
evaluate the health effects associated with
cleanup options, and develops biomonitoring
methods. The  Superfund risk assessment process
involves assessment of toxicity, exposure, and dose
in support of the characterization of risk. The
research provides improved health evaluation
measures to detect, assess, and evaluate the risks
to human health from hazardous substances as
needed for Superfund removal and remedial
cleanup decisions.
  Research will be implemented to evaluate the
additivity assumption now being used in the
assessment of waste mixtures. Test methods will
develop screening techniques for early detection of
adverse health effects, and improved
measurement of health endpoints particularly
non-cancer  endpoints such as reproductive effects
and neurotoxicity. Predictive techniques that can
reduce the uncertainties in risk assessment caused
by data limitations will be developed and site-
specific data will be generated in response to
requests from the Office of Emergency and
Remedial Response, the Office of Waste Programs
Enforcement and EPA Regional Offices.
                     Office or
                     Laboratory   Contact
                            Total      Percent
                            Funds ($k) In-House
                     HERL/RTP
                     OHR/HQ
            Robert Dyer
            Thomas Miller
3,779.2
3,804.5
9.9
 Scientific
 Assessment
Superfund Reportable Quantity
Regulatory Efforts

Chemical-specific data are being provided on
carcinogenicity and chronic effects to support
                               96

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Superfund
                     Program Office activities necessary to adjust, by
                     regulation, the Reportable Quantities (RQ) for
                     hazardous substances. These include listings in
                     association with Section 3001 of Resource
                     Conservation and Recovery Act (RCRA),
                     consideration of Emergency Planning and
                     Community Right-to-Know Act Section 313 (Toxic
                     Release Inventory) chemicals for listing as
                     CERCLA hazardous substances, support for
                     designation of new substances, and review of old
                     RQ calculations to keep them consistent with new
                     data and changes in risk assessment guidelines.
                     Office or
                     Laboratory

                     OHEA/HQ
           Contact

           AlanEhrlich
Total      Percent
Funds ($k)  In-House
 728
25.0
Modeling,
Monitoring
Systems
and Quality
Assurance
Innovative/Alternative Technology
Research, Development, and
Demonstration

Section 31 Ib of the Superfund Amendments and
Reauthorization Act requires EPA to conduct the
Superfund Innovative Technology Evaluation
(SITE) Program, which seeks to accelerate the
application of promising new technologies to
Superfund problems. Examples of technologies
being studied and demonstrated include: fiber
optics chemical sensors for ground water
contamination, immunoassay systems for organic
contamination, canisters for air sampling, x-ray
fluorescence for rapid metals screening,
geophysical equipment for remote sensing of
buried waste, and cone penetrometers for rapid
and extended depth soil sampling.
                    Office or
                    Laboratory   Contact

                    EMSL/LV     Michel Hiatt
                    OMMSQA/HQ  Michael Dellarco
                           Total      Percent
                           Funds ($k)  In-House
                             695.8
            15
                               97

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Superfund
Environmental
Processes and
Effects
Evaluate Technologies to Manage
Uncontrolled Waste Sites

This research activity is focused on evaluating
both naturally -occurring and improved
microorganisms for the degradation of hazardous
substances. Present knowledge and available
biodegradation technology will be expanded to
enable this cleanup technique to be advanced as a
viable option to existing chemical and physical
remediation processes.
  To effect cleanup of hazardous chemicals in the
environment, edaphic and genetic methods to
enhance the biodegradative ability of indigenous
and introduced microorganisms are being studied.
Principles for application of this information to
hazardous waste sites are being developed using
in-situ and above-ground reactor technology. The
program will identify high priority chemical
structures for study, develop  gene banks of novel
capabilities, and develop approaches for rapid
biodegradation. All extramural monies will be
expended by the participating laboratories subject
to final planning actions.
                     Office or
                     Laboratory  Contact
                     RSKERL/ADA
                     ERL/ATH
                     ERL/GB
                     OEPER/HQ
           James F. McNabb
           Rosemarie C. Russo
           Hap Pritchard
           WillC.LaVeille
Total
Funds ($k)

 143.3
  68.2
  68.8
1,897.1
Percent
In-House

  100.0
  100.0
  100.0
    0.0
 Exploratory
 Research
Manage Hazardous Substance Research
Centers Program

Authorized by the 1986 amendments to the
Superfund Act, the Hazardous Substance
Research Centers (HSRC) program supports five
university-based research centers across the
country. The HSRC approach is unique among
federally-sponsored research centers programs.
First, the program has a "Think globally, act
locally" philosophy. Each center is charged with a
global research focus, and a responsibility to act
locally and address problems of the two contiguous
federal region-pair  through technology transfer
                                98

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Superfund
                     activities. To ensure this, the regional community
                     is represented on the required scientific and
                     technology transfer advisory committees for the
                     center. Other members come from industry,
                     government, and academia. This distinctive
                     technology transfer program element at the
                     HSRCs is required and supported by 10-20% of
                     each HSRC's budget. Both technology transfer and
                     research on the effectiveness of different
                     technology transfer techniques and activities,
                     such as workshops and short courses, are included.
                        At least 20% of the total center's resources must
                     be provided by university, state, or private
                     sources. This ensures a continuing commitment to
                     the success of the venture by the universities and
                     other clients of each center.
                        The centers, which consist of multi-university
                     consortia, were selected through a competitive
                     peer review process and established in February
                     1989. Each center has an eight-year life
                     expectancy and receives $1.0 million annually
                     from EPA/OER. In addition, each center is
                     building additional federal and industrial support
                     for their research and technology transfer
                     programs. An additional $1.0 million in grant
                     support from other federal agencies is being
                     provided to the centers this year. An industrial
                     affiliates program is also being established at the
                     centers to facilitate industrial support. This
                     additional support is helping build the reputation
                     of the centers as experts in research and
                     technology transfer for hazardous substance
                     management. The lead institution and research
                     focus of each center include:

                        Region-Pair 1 -2: New Jersey Institute of
                     Technology: Incineration
                        Region-Pair 3-5: The University of Michigan:
                     Bioremediation
                        Region-Pair 4 -6: North Carolina State
                     University: Waste  minimization
                        Region-Pair 7-8: Kansas  State University: Soils
                        Region-Pair 9-10: Stanford University:
                     Groundwater
                                 99

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Superfund
                     Office or
                     Laboratory   Contact
                     EPA/HQ
           Dale Manty
Total      Percent
Funds ($k)  In-House

5,000          0
Exploratory
Research
Small Business Innovation Research
(SBIR) Program—Superfund

EPA is required to devote 1.25% of its extramural
budget to Small Business Innovation Research
(SBIR). The SBIR Program funds, via contracts,
small businesses with ideas relevant to EPA's
mission. Proposals are solicited in the fall of each
year for Phase I research. Phase I research
consists of feasibility studies which are supported
at a level of up to $50,000. Of these Phase I
studies, the best are selected for Phase II studies
where actual product development is started.
Phase II studies are supported up to a level of
$150,000. Results from the SBIR Program are
expected to lead to the commercial development of
a product or process used in pollution control.
Office or
Laboratory   Contact
                     OER/HQ
           Donald Carey
Total      Percent
Funds ($k)  In-House

 692         0
Exploratory
Research
Superfund Research Grants

The Superfund research grants program supports
research initiated by individual investigators in
areas of priority interest to the Agency. Research
proposals are solicited via the Request for
Applications (RFA), which is a targeted
solicitation mechanism that identifies Agency
research needs in well-defined areas. Only
proposals which specifically address those needs
are accepted for review and possible funding.
                     Office or
                     Laboratory   Contact
                     OER/HQ
           Roger Cortesi
Total      Percent
Funds ($k)  In-House

2,400         0
                               100

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Superfund
 Environmental
 Processes and
 Effects
Field Screening Techniques for
Assessment and Evaluation

This research activity is designed to develop
procedures for evaluating the ecological hazards
and risks associated with hazardous waste sites
and their remedial operations. Ecological
endpoints, important to the Superfund program,
will be identified and appropriate methods for
evaluating the ecological hazards and risks
associated with hazardous wastes at Superfund
sites will be validated. Available methods will be
customized to the extent possible to provide site-
specific field assessment methods.
  A second purpose is to acquire subsurface
process and characterization information that will
allow development of a decision-making
framework for evaluating the appropriateness and
potential efficacy of remediation technologies such
as pump-and-treat and various
physical/chemical/biological methods. The
program will consist of studies on methods for site
characterization, immiscible fluid flow and
residual saturation, mass transport in
heterogenous media, and accelerated remediation
methods.
                     Office or
                     Laboratory   Contact

                     RSKERL/ADA James F. McNabb
                     ERL/ATH     Rosemarie C. Russo
                     ERL/NARR    Gerald G. Pesch
                     OEPER/HQ    Will C. LaVeille
                            Total      Percent
                            Funds ($k)  In-House
                            1.075.0
                              82.4
                             384.0
                             250.0
 0.0
41.5
 0.0
 0.0
                                101

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Overview
Introduction

The primary goal of the U.S. Environmental Protection Agency is to
mitigate the adverse impacts of pollution on human health and the
environment. Toward that end, Agency management must make decisions
regarding the development of policy, guidance, standards, regulations, and
the appropriate tools for implementing pollution abatement strategies. It
is the primary mission of the Office of Research and Development (ORD) to
provide high quality, timely scientific and technical information in the
service of Agency goals. The Agency's research program is conducted
through 12 environmental laboratories across the country, employing
some 1900 people, with an annual budget of about $450 million. The
research focuses on areas targetted by the planning process as needing
additional emphasis in order to provide the  information required for
Agency decision making.
Research Perspectives

The overall planning process engenders an applied research and
development program focused on answering key scientific and technical
questions related to EPA's decision making, short-term scientific and
technical studies supporting immediate regulatory and enforcement
decisions. In addition, ORD maintains a longer-term core research
program that extends the knowledge base of environmental science and
anticipates environmental problems. This research and development
program is focused on the following functional areas:

•  Health effects research—to determine exposure and adverse effects of
   pollutants on human health

•  Ecological effects research—to determine exposure and adverse effects
   of pollutants on ecosystems

•  Environmental process and fate research—to understand how
   pollutants are transported and modified as they move through soils,
   ground and surface waters, and the atmosphere

•  Environmental monitoring research—to develop methods of identifying
   pollutants in the environment and measuring exposure to such
   substances

•  Risk assessment research—to develop methods to integrate information
   on pollutant sources, fate and transport, exposure, and health and
   ecological effects in order to assess the overall risk posed by a pollutant
   or a group of pollutants
                                102

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Overview
• Risk reduction research—to develop control technologies to treat,
  destroy, or contain pollutants and methods to reduce or eliminate the
  sources of pollutants or to prevent exposure to pollutants.

  In addition to functional areas, several cross-media problems also
categorize the total ORD program. Those cross- media problems receiving
special emphasis at present and for the foreseeable future and the Agency
programs most concerned are:

• Global climate change (air, water, hazardous waste);

• Environmental Monitoring and Assessment (water, air, energy);

• Total and human exposure assessment (air, water, hazardous
  waste/superfund, pesticides/toxic substances);

• Ground Water (water, hazardous waste/superfund);

• Pollution Prevention (hazardous waste, pesticides, multimedia);

• Comparative risk for complex mixtures (air, water, hazardous
  waste/superfund, pesticides/toxic substances); and

• Technology Transfer (all).

Conclusions

ORD's ongoing activities evolve from a process of mediation between
research concepts and regulatory/programmatic applications, as well as
from a growing fund of commonly held priorities and core values. As the
Agency continues to refine strategies for addressing increasingly complex
environmental problems, the goal of ORD is to affect those strategies with
sound science, sound judgment, and vision.
                                103

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              _L
      Office of Research
    Program Management
    Clarence Mahan, Dir
   Office of Modeling,
  Monitoring Systems &
   Quality Assurance
   Rick Lmthurst, Dir
        Atmospheric
         Research &
          Exposure
        Assessment
        Lab .Research
      Triangle Park, NC
       Gary Foley, Dir
        Environmental
     Monitoring Systems
     Lab, Cincinnati, OH
       Tom Clark, Dir
        Environmental
     Monitoring Systems
     Lab ,Las Vegas, NV
       Robert Snelling,*
             Dir
"Acting
                             Assistant Administrator for
                             Research and Development
                                  Erich Bretthauer
                           Deputy Assistant Administrator
                                  John H  Skinner
 Office of Environmental
Engineering & Technology
     Demonstration
   Alfred Lmdsey, Dir
        Air & Energy
    Engineering Research
       Lab , Research
      Triangle Park, NC
     Frank Princiotta, Dir
       Risk Reduction
      Engineering Lab,
       Cincinnati, OH
     Timothy Oppelt, Dir
                                 Office of Exploratory
                                      Research
                                 Roger S  Cortesi. Dir.
Office of Environmental
  Processes & Effects
      Research
 Courtney Riordan, Dir
 Environmental Research
    Lab .Corvallis, OR
  Thomas Murphy, Dir
                                 Environmental Research
                                    Lab .Athens, GA
                                 Rosemane  Russo, Dir
 Environmental Research
    Lab .Duluth, MN
    Oilman Veith, Dir
                                 Environmental Research
                                  Lab .Narragansett, Rl
                                  Norbert Jaworski, Dir
                                 Environmental Research
                                  Lab ,Gulf Breeze, FL
                                 Robert E Menzer, Dir
                                                               R S Kerr Environmental
                                                               Research Lab .Ada, OK
                                                                  Clinton Hall, Dir
Office of Health
   Research

Ken Sexton, Dir
  Health Effects
  Research Lab ,
 Research Triangle
     Park, NC
 Lawrence Reiter,
       Dir
                            Office of Technology
                            Transfer & Regulatory
                                  Support
                              Peter Preuss, Dir
 Office of Health &
   Environmental
    Assessment
William Farland, Dir
    Human Health
  Assessment Group
  Hugh McKmnon, Dir
                                                               Exposure Assessment
                                                                      Group
                                                               Michael Callahan, Dir
                             Environmental Criteria
                             & Assessment Office,
                               Research Triangle
                                   Park, NC
                               Lester Grant,  Dir
                                                               Environmental Criteria
                                                               & Assessment Office,
                                                                  Cincinnati, OH
                                                               Christopher DeRosa,'
                                                                       Dir

-------
ORD Organization
Please note, the list below includes both commercial (CML) and Federal
(FTS) telephone numbers. Where only one number is listed, it serves both
purposes.


Assistant Administrator for Research and Development

  Erich Bretthauer                                 (202) 382-7676
  Headquarters, Washington, DC (RD-672)
Deputy Assistant Administrator

  John H. Skinner
  Headquarters, Washington, DC (RD-672)
     (202) 382-7676
Senior ORD Official, Cincinnati

  Acting Director, Steven Lutkenhoff
  Cincinnati, OH 45268

  Support Services Office
   Director, Robert N. Carr
CML (513) 569-7951
    FTS 8-684-7951

CML (513) 569-7966
    FTS 8-684-7966
Senior ORD Official, Research Triangle Park

  Elizabeth J. Hudson
  Research Triangle Park, NC 27711
CML (919) 541-0179
    FTS 8-629-0179
Office of Technology Transfer and Regulatory Support
  Director, Peter W. Preuss
  Headquarters, Washington, DC (H-8105)

  Regulatory Support Staff
   Director, Jay Benforado

  Technology Transfer Staff
   Director, Mike Moore
     (202) 382-7669



     (202) 382-7669


     (202) 382-7671
                              105

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ORD Organization
  Center for Environmental Research
  Information (CERI)
   Director, Calvin Lawrence
   Cincinnati, OH 45268

  Regional Operations Staff
   Director, David Klauder
     Regional Scientist Program Coordinator,
       (Vacant)
CML (513) 569-7391
    FTS 8-684-7391
     (202) 382-7667

     (202) 382-7667
Office of Research Program Management

  Director, Clarence E. Mahan
  Deputy Director, W. Randall Shobe
  Headquarters, Washington, DC (RD-674)

  Evaluation and Review Staff
   Chief, Thomas L. Hadd

  Planning Staff
   Chief, Clifford Moore

  Program and Information Management Staff
   Chief, Linda K. Smith

  Program Coordination Staff
   Chief, Peter Durant
     (202) 382-7500
CML (202) 382-7659
    FTS 8-382-7659

CML (202) 382-2597
    FTS 8-382-2597

CML (202) 382-7462
    FTS 8-382-7462

CML (202) 382-7468
    FTS 8-382-7468
Office of Exploratory Research

  Director, Roger Cortesi
  Headquarters, Washington, DC (RD-675)

  Research Grants Staff
    Director, Robert Papetti

  Research Centers Program
    Director, Karen Morehouse

  Visiting Scientists Program
    Coordinator, Alvin Edwards

  Small Business Innovation Research Program
    Director, Donald Carey
     (202) 382-5750



     (202) 382-7473


     (202) 382-5750


     (202) 382-7473


     (202) 383-7445
                               106

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ORD Organization
Office of Health Research

  Director, Ken Sexton                                (202)382-5900
  Deputy Director, David Kleffman
  Headquarters, Washington, DC (RD-683)

  Program Operations Staff
    Director, Mary Ellen Radzikowski                   (202) 382-5891

  Environmental Health Research Staff
    Director, David Kleffman (Acting)                   (202) 382-5893

  Health Effects Research Laboratory
    Director, Lawrence W. Reiter (MD-51)          CML (919) 541-2281
    Deputy Director, Harold Zenick                    FTS 8-629-2281
Office of Modeling, Monitoring Systems and Quality Assurance

  Director, Rick A. Linthurst                           (202) 382-5767
  Deputy Director, H. Matthew Bills
  Acting Associate Director, Jack Puzak                 (202) 382-5776
  Headquarters, Washington, DC (RD-680)

  Program Operations Staff
    Director, Paul D. Palm                             (202) 382-5761

  Quality Assurance Management Staff
    Acting Director, Nancy Wentworth                  (202) 382-5763

  Modeling and Monitoring Systems Staff
    Director, Frederick W. Kutz                        (202) 382-5776

  Atmospheric Research and Exposure
  Assessment Laboratory
    Director, Gary J. Foley                        CML (919) 541-2106
    Acting Deputy Director, William J. Mitchell         FTS 8-629-2106
    Research Triangle Park, NC 27711

  Environmental Monitoring Systems
  Laboratory
    Director, Thomas A. Clark                    CML (513) 569-7301
    Deputy Director, Gerald D. McKee                 FTS 8-684-7301
    Cincinnati, OH  45268
                               107

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ORD Organization
  Environmental Monitoring Systems
  Laboratory
   Acting Director, Robert N. Snelling             CML (702) 798-2525
   Acting Deputy Director, Llewellyn R. Williams       FTS 8-545-2525
   P.O. Box 93478
   Las Vegas, NV 89193-3478

  Vint Hill Station
   Acting Director, Donald Garofalo               CML (703) 347-6224
   P.O. Box 1587, Building 166                       FTS 8-557-3110
   Warrenton,VA22186
Office of Health and Environmental Assessment

  Director, Willilam H. Farland                   CML (202) 382-7315
  Headquarters, Washington, DC (RD-689)             FTS 8-382-7315

  Program Operations Staff                      CML (202) 382-7311
   Chief, Barry Goldfarb                            FTS 8-382-7311
  Program Liaison Staff                          CML (202) 382-7323
   Chief, Jerry Moore                               FTS 8-382-7323

  Technical Information Staff                     CML (202) 382-7345
   Chief, Marie Pfaff                                FTS 8-382-7345

  Human Health Assessment Group               CML (202) 382-7338
   Director, Hugh McKinnon                         FTS 8-382-7338

  Exposure Assessment Group                    CML (202) 475-8909
   Director, Michael Callahan                       FTS 8-475-8909

  Environmental Criteria and Assessment
  Office
   Director, Lester Grant (MD-52)                CML (919) 541-4173
   Research Triangle Park, NC 27711                 FTS 8-629-4173

  Environmental Criteria and Assessment
  Office
   Acting Director, Christopher DeRosa           CML (513) 569-7531
   Cincinnati, OH 45268                            FTS 8-684-7531
                               108

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ORD Organization
Office of Environmental Engineering and Technology
Demonstration

  Director, Alfred Lindsey                            (202) 382-2600
  Deputy Director, Stephen Lingle
  Headquarters, Washington, DC (RD-681)

  Program Development Staff
   Director, Greg Ondich                            (202) 382-5748

  Program Management Staff
   Director, Al Galli                                 (202) 382-2583
   Deputy Director, Steve Jackson

  Field Laboratories

   Air and Energy Engineering Research
   Laboratory
     Director, Frank Princiotta (MD-60)            CML (919) 541-2821
     Deputy Director, Blair Martin                   FTS 8-629-2821
     Research Triangle Park, NC 27711
   Risk Reduction Engineering Laboratory
     Director, E. Timothy Oppelt                 CML (513) 569-7418
     Deputy Director, John Convery                  FTS 8-684-7418
     Cincinnati, OH 45268

       Releases Control Branch
       Chief, Jack Farlow                        CML (201) 321-6635
       Edison, NJ 08817                            FTS 8-340-6635
Office of Environmental Processes and Effects Research

  Director, Courtney Riordan                          (202) 382-5950
  Deputy Director, Michael W. Slimak
  Headquarters, Washington, DC (RD-682)

  Program Operations Staff
    Director, Patricia M. Neuschatz                    (202) 382-5962

  Terrestrial and Ground Water Effects Staff
    Director, Jack Durham                            (202) 475-8930

  Marine, Freshwater and Modeling Staff
    Acting Director, Robert R. Swank                  (202) 382-5791
                               109

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ORD Organization
  Field Laboratories

   Robert S. Kerr Environmental Research
   Laboratory
     Director, Clinton W. Hall                   CML (405) 332-8800
     P.O. Box 1198                                 FTS 8-743-2224
     Ada, OK 74820

   Environmental Research Laboratory
     Director, Rosemarie C. Russo                CML (404) 546-3134
     Acting Director for Research
       Operations, John E. Rogers
     College Station Road                           FTS 8-250-3134
     Athens, GA 30613

   Environmental Research Laboratory
     Director, Thomas A. Murphy                 CML (503) 757-4601
     Deputy Director.Robert T. Lackey                FTS 8-420-4601
     200 SW 35th Street
     Corvallis, OR 97333

   Environmental Research Laboratory
     Director, Oilman D. Veith                   CML (218) 727-6692
     Associate Director for Research,                 FTS 8-780-5550
       Steven F. Hedtke
     6201 Congdon Boulevard
     Duluth, MN 55804

     Monticello Field Station                             CML only
     Box 500                                       (612)295-5145
     Monticello, MN 55362

     Large Lakes Research Station               CML (313) 692-7600
     9311 Groh Road                                FTS 8-378-7600
     GrosseIle,M148138

   Environmental Research Laboratory
     Director, Norbert A. Jaworski               CML (401) 782-3001
     Deputy Director, (Vacant)                       FTS 8-838-6001
     South Ferry Road
     Narragansett, RI 02882

     Hatfield Marine Science Center                       CML only
     Newport, OR 97365                             (503) 867-4040

   Environmental Research Laboratory
     Director, Robert E. Menzer                  CML (904) 934-9200
                               110

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ORD Organization
    Deputy Director, Raymond G. Wilhour          FTS 8-228-9200
    Sabine Island
    Gulf Breeze, FL 32561
                         111

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ORD Organizational Descriptions
 Office of
 Technology
 Transfer and
 Regulatory
 Support
The Office of Technology Transfer and Regulatory
Support (OTTRS) is responsible for three broad
functions. The first function is to ensure that the
Agency's regulations, legislation, and other policy
decisions are based on the best scientific and
technical information available. OTTRS staff
coordinates the input from ORD offices and
laboratories to the regulations and participates at
all levels of the regulatory process. The second
function, technology transfer, implements a
program to share the results of ORD's research
and development outside the Agency. In
coordination with the laboratories and program
offices, OTTRS and the Center for Environmental
Research Information (CERI) develop technology
transfer products. Those products include
databases, publications, seminars, and workshops
which are available to state and local
governments,  academia, international
organizations, as well as others with an interest in
environmental science and technology. The third
function, regional operations, is the ORD liaison
with EPA's regional offices. Regional operations
staff promotes regional interests in the research
planning process as well as technology transfer
through the Regional Scientist Program and the
Regional Superfund Technical Liaison Program.
 Office of
 Exploratory
 Research
The Office of Exploratory Research (OER) is
responsible for planning, administering,
managing and evaluating EPA's exploratory
research program in general and, in particular, its
extramural grant research in response to Agency
priorities as established by Agency planning
mechanisms. Its basic objective is to support
research aimed at developing a better basic
scientific understanding of the environment and
its inherent problems. OER accomplishes this
objective through several core programs: a
Competitive Research Grants Program, an
Environmental Research Centers Program, a
Hazardous Substance Research Centers Program,
a Visiting Scientists Program and a Small
Business Innovation Research Program. Separate
                               112

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ORD Organizational Descriptions
                     descriptions of these programs are provided
                     elsewhere in this research guide. In addition to the
                     core programs, OER administers other programs
                     which are not supported by research and
                     development funds appropriated to OER but are
                     nonetheless important to the accomplishment of
                     the OER objective. They include:
                     • A Minority Fellowship Program which awards
                       fellowships to college seniors and graduate
                       students enrolled on a full-time basis at
                       Historically Black Colleges and Universities
                       and majoring in curricula that could be applied
                       to the solution of environmental problems.
                     • A Minority Summer Intern Program which
                       extends to recipients of fellowships under the
                       Minority Fellowship Program the opportunity
                       for hands-on experience in the area of their
                       academic training by way of a summer
                       internship at an EPA or other environmental
                       facility. (Both the Minority Fellowship Program
                       and the Minority Summer Intern Program are
                       components of the Minority Institutions
                       Assistance Program, which is briefly described
                       elsewhere in this document.)
                     • The Agency's Senior Environmental
                       Employment Program (SEE) which utilizes the
                       skills and talents of older Americans to meet
                       employment needs of environmental programs.
                     • The Federal Workforce Training Program
                       which coordinates ORD's participation in
                       workforce training programs used by state and
                       local  governments.
                     • The Resident Research Associateship Program
                       (RRAP) which, through a cooperative with the
                       National Research Council, attracts scientists
                       and engineers to ORD laboratories for one-year
                       assignments to conduct research needed by the
                       Agency. The program sponsors the research of
                       junior, mid-, and senior-level scientists and
                       engineers.
                               113

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ORD Organizational Descriptions
 Office of
 Environmental
 Engineering
 and
 Technology
 Demonstration
The Office of Environmental Engineer ing and
Technology Demonstration is responsible for the
assessment and the development of methods for
control of the environmental and socio-economic
impacts of municipal and industrial operations
and of energy and mineral resource extraction,
processing,  conversion, and utilization systems.
  The Risk Reduction Engineering Laboratory in
Cincinnati,  Ohio, investigates ways to prevent,
control, and treat hazardous wastes and
Superfund related activities. This includes
defining and characterizing sources of pollution,
catalyzing advances in the state-of-the-art of
pollution control, providing engineering concepts
for cost-effective engineering solutions to difficult
pollution problems and early-warning of emerging
sources of pollution.
  It also investigates, develops and demonstrates
cost-effective methods for the treatment and
management of municipal waste water and sludges
and urban runoff; and of industrial processing and
manufacturing and toxic discharges, and the
development of technology and management
systems for  the treatment, distribution and
presentation of public drinking water supplies.
• Drinking Water: This research program
  integrates chemistry, engineering,
  microbiology, and cost to provide effective,
  reliable, and cost-effective techniques for
  assuring  the delivery of safe drinking water to
  reduce the risk of chemically and
  microbiologically induced health effects to the
  public. Included are laboratory, pilot plant, and
  field studies on control of lead, radon, synthetic
  organics, disinfection by-products, viruses, and
  cysts.
• Hazardous Wastes: This program focuses on
  investigating incineration, land disposal and
  alternative technologies for treating,
  detoxifying, and disposing of hazardous wastes.
• LUST Trust Fund Technical Support: This
  program  works in close support to the Office of
  Underground Storage Tanks (OUST) to develop
  procedures for detecting and preventing leaks
  from storage tanks and associated piping.
                               114

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ORD Organizational Descriptions
                       Under the LUST Trust Fund, technical
                       assistance is provided on site assessment,
                       technology selection, and corrective action to
                       decision officials.
                     • Pesticides: This research program evaluates
                       processes for treating wastes from production,
                       application and disposal of pesticides. The
                       program also evaluates treatment alternatives
                       for disposing cancelled and suspended
                       pesticides, and provides data and guidance on
                       the effectiveness of protective equipment for
                       reducing worker exposure to pesticides.
                     • Superfund: Research is directed at identifying,
                       developing and evaluating technologies to
                       support remediation, removal and enforcement
                       actions. The Superfund Innovative Technology
                       Evaluation (SITE) program facilitates
                       development and conducts demonstrations of
                       innovative technologies as alternatives to
                       containment. The Superfund Technical
                       Assistance Response Team (START) provides
                       engineering and scientific assistance to
                       Regional Offices, Program Offices, and others
                       on the cleanup of hazardous wastes,
                       particularly those associated with Superfund
                       sites.
                     • Toxic Chemical Testing and Assessment: One
                       goal of this research program is to provide test
                       protocols, treatment and control procedures for
                       regulating the manufacture and use of existing
                       toxic chemicals (including asbestos); assessing
                       release and exposure in review of
                       Premanufacturing Notices (PMNs) for new
                       chemicals; and evaluating techniques and
                       devices to contain and destroy genetically
                       engineered organisms are  two other goals.
                     • Wastewater Treatment (Municipal and
                       Industrial): Research efforts are focused on
                       developing cost-effective methods for treating
                       municipal wastewater and sludges, urban
                       runoff, and industrial  wastewater discharges
                       from processing and manufacturing operations.
                       The main goal is to provide design and
                       operating guidelines for efficient wastewater
                       management based on the  principles of
                               115

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ORD Organizational Descriptions
                        pollution prevention and process integration.
                        The research also includes the development of
                        toxicity-based permitting via use of bioassay
                        procedures.
                     •  Municipal Waste: This program promotes the
                        integration of municipal solid waste
                        management technologies through research on
                        safe and effective recycling practices, reducing
                        multimedia pollutant releases from municipal
                        land disposal facilities, and research on the
                        utilization and safe disposal of municipal waste
                        combustion residues.
                     •  Pollution Prevention: Research is conducted, (1)
                        to assess opportunities for multi-media
                        pollution prevention through source reduction
                        and recycling within operating industrial
                        facilities: (2) to develop and demonstrate
                        innovative pollution prevention technologies
                        for industrial and transportation sector
                        processes; (3) to develop and standardize
                        methodologies for performing consumer product
                        life cycle analyses and for measuring waste
                        reduction.
                     •  Oilspills: As a result of EPA's involvement in
                        efforts to clean up the Alaskan oil spill,
                        research is underway to develop and evaluate
                        remediation technologies. The program
                        emphasizes exploiting the natural ability of
                        indigenous microorganisms to degrade oil, with
                        or without nutrient addition.
                        The major purpose of the Air and Energy
                     Engineering Research Laboratory is to develop and
                     assess methods and technologies for preventing, or
                     reducing the effects of air pollutants on human
                     health and welfare, and on the global
                     environment.
                     •  Acid Rain: This program focuses on developing
                        innovative controls for acid rain precursors,
                        SC>2 and NO _ including the Limestone Injection
                        Multistage fiurner; developing models that will
                        identify the best possible control alternatives
                        for various scenarios; and developing
                        inventories of acid rain precursor emissions.
                                116

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ORD Organizational Descriptions
                     • Air Toxics: Emphasis is placed on developing
                       technologies and pollution prevention
                       approaches to reduce emissions of volatile
                       organic compounds (VOCs); identifying sources
                       of VOCs; developing improved designs that will
                       achieve better control of woodstove emissions;
                       and providing direct technical assistance to
                       state and local agencies through the Control
                       Technology Center (CTC) which has extensive
                       information on existing technologies applicable
                       to a variety of air pollution sources.
                     • Hazardous Wastes: The primary goal of this
                       program is to study the fundamental
                       combustion mechanisms that influence thermal
                       destruction of hazardous wastes. Included are
                       studies of metal aerosols from waste
                       incineration, failure modes in a small pilot-
                       scale rotary kiln, and small pilot-scale studies
                       of fluidized-bed incineration.
                     • Indoor Air Quality/Radon: Research is
                       currently concentrating on (1) developing and
                       demonstrating technologies for reducing the
                       entry of naturally-occurring radon into houses,
                       schools and other public buildings; (2) studying
                       emissions from building materials and
                       consumer products as sources of indoor air
                       pollution; (3) evaluating the effects of "sinks"
                       that adsorb/desorb pollutants in the indoor
                       environment; and (4) evaluating indoor air
                       control options for gases and particles.
                     • Municipal Waste Combustion: Work focuses on
                       evaluating techniques to minimize pollutant
                       formation during combustion, and determining
                       the effectiveness of various devices in
                       controlling air pollution from municipal waste
                       incinerators.
                     • Ozone Non-Attainment: This program supports
                       ORD"s overall ozone non-attainment strategy
                       by developing innovative technologies,
                       mitigation strategies, process modifications and
                       improving existing technologies which will
                       prevent, or reduce, the emission of
                       hydrocarbons, nitrogen oxides and VOCs.
                               117

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ORD Organizational Descriptions
                    •  Stratospheric Ozone: In cooperation with
                       industry, AEERL evaluates, identifies, and
                       recommends substitute products and new
                       industrial processes which will replace ozone
                       depleting substances that are now in use. The
                       current emphasis is on alternatives for home
                       and commercial refrigeration systems.
                    •  Global Climate Change: This program is
                       evaluating mitigation options for greenhouse
                       gases (carbon dioxide, methane, nitrous oxide)
                       including innovative technological solutions to
                       the problem. Also planned are inventories of
                       emissions that are contributing to global
                       climate change.
Office of
Health
Research
The Office of Health Research is responsible for
developing and evaluating toxicity test methods
and for providing toxicity data to enable the
Agency to accurately identify hazards and
determine human risk from environmental
exposure. To fulfill this mission, research is
conducted in three major areas:

— Toxicity test method development

— Generation of dose-response data

— Development of methods to use data from
  toxicity testing and dose-response studies to
  estimate human morbidity and mortality;
  including extrapolation from animal data to
  human effects, from high to low doses, from
  acute toxicity to long-term effects, and from
  exposure to dose.
  The Health Effects Research Laboratory (HERD
in Research Triangle Park, North Carolina,
conducts research, both intramurally and
extramurally, which is responsive to these goals.
Physical, biological  and chemical agents are
studied; and research is conducted in the scientific
disciplines of pulmonary toxicology, genetic
toxicology, neurotoxicology, developmental and
reproductive toxicology, and epidemiology and
biometry. Research to improve the quality of
health risk assessment is being conducted through
                               118

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ORD Organizational Descriptions
                     the development of pharmacokinetic and
                     biologically based models. These models are being
                     developed to more accurately predict the
                     relationship between environmental
                     concentration, target tissue dose and ultimate
                     health effect.
Office of
Environmental
Processes and
Effects
Research
The Office of Environmental Processes and Effects
Research is responsible for the administration of a
broad range of ecological research programs.
These programs are structured to provide the
scientific data and technological methods
necessary to understand the the entry and
movement of pollutants into the environment and
to determine the effects of such substances on
organisms and ecosystems. The information and
research products resulting from these programs
are directly applicable to fulfilling the Agency's
regulatory responsibilities.
  Research is conducted within the full realm of
environmental media—atmosphere, soil, ground
water, surface water, and coastal and marine
waters. Major areas of study include toxic
substances, hazardous waste, pesticides, acid
deposition, biotechnology, global climate change,
stratospheric ozone, wetlands, water quality,
ecological risk assessment,and status of critical
ecological resources. The Office actively provides
technical support in environmental science and
technology to regions and States in order to assist
in problem solving and to transfer information and
technology to local users.
  The Robert S. Kerr Environmental Research
Laboratory in Ada, Oklahoma, serves as U.S.
EPA's center for ground water research, focusing
its efforts on studies of the transport and fate of
contaminants in the subsurface, development of
methodologies for protection and restoration of
ground-water quality, and evaluation of the
applicability and limitations of using natural soil
and subsurface processes for the treatment of
hazardous wastes. Subsurface transport and fate
information is incorporated into mathematical
models for use in predicting the transport and fate
of contaminants in the subsurface. Efforts to
                               119

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ORD Organizational Descriptions
                     support the immediate needs and activities of
                     EPA's operating programs are focused on the
                     Underground Injection Control Program, the
                     Wellhead Protection Program and the Hazardous
                     Waste and Superfund Programs. RSKERL's
                     Technology Support Program provides decision-
                     makers with a source of information on subsurface
                     fate and transport of contaminants and in situ
                     remediation  technologies, as well as the associated
                     expert assistance required to effectively use this
                     information.
                       The Environmental Research Laboratory in
                     Athens, Georgia, conducts and manages
                     fundamental and applied research to predict and
                     assess the human and environmental exposures
                     and risks associated with the release of pollutants
                     in freshwater, marine, and terrestrial ecosystems.
                     The research focus is predictive ecological
                     science—predictive pollutant fate, predictive
                     exposure assessment,  and predictive ecological
                     risk assessment and eco-resource management.
                       The research identifies and characterizes the
                     natural biological and chemical processes that
                     affect the environmental fate and effects of specific
                     toxic substances, such as pesticides or metals. The
                     results are applied in state-of-the-art
                     mathematical models for assessing and managing
                     environmental pollution problems. Emphasized
                     research areas in FY91 are global climate change,
                     ecological risk assessment, sediment quality
                     evaluation, artificial intelligence-expert systems
                     for predicting chemical reactivity, bioremediation,
                     and wellhead protection.
                       EPA's Center for Exposure Assessment
                     Modeling (CEAM) an internationally known
                     center of modeling expertise located at the Athens
                     Lab, provides models, training, and applications
                     support for multimedia exposure evaluation and
                     ecological risk assessment. CEAM assists the
                     Agency and States in environmental risk-based
                     decisions concerning the protection of freshwater,
                     marine water, soil, ground water, and air.
                       The Environmental Research Laboratory in
                     Corvallis, Oregon, conducts research on terrestrial
                     and watershed ecology and assesses the
                     comprehensive ecological impact of inland
                     pollution and other environmental changes caused
                                120

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ORD Organizational Descriptions
                     by man. This includes the ecological effects of
                     airborne pollutants, such as acid deposition; the
                     ecological effects of global climate and UV-B
                     changes, the effects of toxic chemicals on
                     terrestrial plants, animals, and ecosystems; the
                     assessment and restoration of contaminated or
                     degraded environments; the characterization and
                     assessment of the vulnerability of ecological
                     systems such as wetlands, to human impacts; and
                     the ecological risks from the terrestrial release of
                     bioengineered organisms and other biological
                     control agents.
                       The Environmental Research Laboratory in
                     Duluth, Minnesota, is primarily responsible for
                     developing water quality criteria and other
                     measures of ecological health for the Nation's
                     freshwaters. The mission of this laboratory is to
                     develop methods for predicting and assessing the
                     effects of pollutants and pollution activities on
                     freshwater resources. Located on Lake Superior,
                     the laboratory specializes in the toxicology of
                     industrial chemicals, pesticides, and other
                     hazardous substances. Primary research programs
                     include developing ecosystem response models,
                     diagnostic methods for watersheds and mass
                     balance ecosystem models for the Great Lakes.
                       ERL-Duluth continues to conduct its research
                     in surface freshwater systems, both flowing and
                     lakes, including the Great Lakes (Gross He, MI)
                     and freshwater wetlands (Monticello, MN).
                     Research programs center on stresses from water
                     criteria pollutants, xenobiotics and biological
                     stressors including climate changes and
                     sediments. Investigations focus on the impact of
                     these stresses through a risk assessment
                     framework including stressor source assessment,
                     classification/characterization, hazard
                     identification and stressor dose-response analysis.
                       The Environmental Research Laboratory at
                     Narragansett, Rhode Island, along with its Pacific
                     Coast laboratory in Newport, Oregon, is the
                     Agency's National Marine Environmental Quality
                     Research and Monitoring Laboratory. The
                     Laboratory's research and monitoring efforts
                     support primarily the EPA Office of Water, Office
                     of Emergency and Remedial Response, and the
                     Office of Air and Radiation. The Laboratory efforts
                               121

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ORD Organizational Descriptions
                     respond mainly to legislative requirements of the
                     Clean Water Act, the Marine Protection, Research
                     Sanctuaries Act, Clean Air Act, and the Superfund
                     Reauthorization Act. Major emphasis is placed on
                     providing the scientific base for environmental
                     criteria, waste disposal practices, environmental
                     analysis and impacts, assessments of marine and
                     estuarine risk of regulatory activities by
                     responsible offices.
                        The principal research and monitoring themes
                     of the Laboratory reflect its major strengths and
                     are critical to accomplish the Laboratory's mission
                     and the Ecological Risk Assessment Program of
                     the Agency. The Laboratory's major themes are:
                     (1) Predictive Biological Test Method
                     Development; (2) Ecological Processes and
                     Significance; (3) Environmental Exposure and
                     Chemistry; and (4) Ecological Indicators and
                     Monitoring.
                        The Laboratory is responsible for the following
                     research and program areas: (1) marine and
                     estuarine disposal; (2) water use designation and
                     derivation of criteria for marine and estuarine
                     water and sediment; (3) environmental
                     assessment of ocean disposal and discharges of
                     waste and wastewaters; (4) technical and research
                     support for evaluating remediation options at
                     proposed and designated marine/estuarine
                     Superfund sites; (5) research on the effects of
                     global warming and the depletion of stratospheric
                     ozone on marine systems; and (6) ecological
                     monitoring for Near Coastal Ecosystems (EMAP).
                     Technical assistance, technology transfer, and
                     investigations of an emergency nature, e.g., spills
                     of toxic materials, are also are provided to aid EPA
                     offices in evaluating environmental threats posed
                     by toxicants, other pollutants,  and physical
                     modifications along  our nation's coasts. Technical
                     assistance is also provided to other Federal
                     agencies, states, municipalities, and industry.
                        The Environmental Research Laboratory in
                     Gulf Breeze, Florida, has broad research objectives
                     which include the development of scientific
                     information for (1) formulation of guidelines,
                     standards, and strategies for management of
                     pesticides and toxic chemicals  in the near-coastal
                     marine environment, (2) definition of current
                                122

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ORD Organizational Descriptions
                     ecological "health" status and measurement and
                     prediction of changes in ecological structure and
                     function over time, (3) description of cause(s) of
                     aberrant conditions or observed changes in
                     ecological status, and (4) application of biological
                     systems to bioremediate toxic and hazardous
                     chemicals in the environment. Research is
                     primarily devoted to chemical compounds and
                     biological products regulated by EPA's Office of
                     Pesticides and Toxic Substances, the Office of
                     Water Programs, and the Office of Solid Waste and
                     Emergency Response.
                       Research programs specifically addressed by
                     the Laboratory include (1) definition and
                     evaluation of factors and mechanisms that affect
                     biodegradation rates and bioaccumulation
                     potential in food-webs; (2) development of
                     procedures and evaluation protocols for the
                     biological treatment of toxic chemicals and
                     hazardous wastes in the environment; (3)
                     determination of effects of carcinogens, mutagens,
                     and teratogens in aquatic species; (4) development
                     of principles and applications of ecotoxicology,
                     including measurements and predictions of the
                     fate and effects of chemicals and biotechnological
                     products on  estuarine organisms,  populations,
                     communities, and associated ecological structure
                     and function; (5) development and verification of
                     methods and data that allow extrapolation of
                     effects from laboratory observations to field
                     situations, within and among species, populations,
                     communities, and ecosystems; (6)  development of
                     methods to evaluate the environmental risk of
                     toxic chemicals and products of biotechnology to
                     the marine environment; and (7) environmental
                     monitoring and assessment of bays and estuaries
                     of the Gulf of Mexico to define ecological "health"
                     status and to define changes over time and
                     cause(s).
                               123

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ORD Organizational Descriptions
Office of
Modeling,
Monitoring
Systems and
Quality
Assurance
The Office of Modeling, Monitoring Systems and
Quality Assurance (OMMSQA) is responsible for:
(a) research with respect to the characterization,
transport, and fate of pollutants which are
released into the atmosphere; (b) development and
demonstration of techniques and methods to
monitor and model human and ecological exposure
and to relate ambient concentrations to exposure
by critical receptors; (c) research, development and
demonstration of new monitoring methods,
systems, techniques, and equipment for detection,
identification and characterization of pollutants at
the source and in the ambient environment and for
use as reference or standard monitoring methods;
(d) management and oversight of the Agency-wide
quality assurance program; and (e) development
and provision of quality assurance methods,
techniques and material  including validation and
standardization of analytical methods, sampling
techniques, quality control methods, standard
reference materials, and techniques for data
collection, evaluation and interpretation.
   The Environmental Monitoring Systems
Laboratory in Las Vegas, Nevada, conducts
research and development programs related to: (a)
monitoring of pollutants  in the environments; (b)
developing sampling strategies and techniques for
monitoring hazardous waste leachates in soil and
groundwater; (c) developing remote sensing
techniques; (d) conducting human exposure
monitoring and modeling studies covering several
environmental media; (e) evaluating analytical
methods for the characterization and
quantification of hazardous wastes; and (f)
providing quality assurance in support of the
EPA's hazardous waste, Superfund, pesticides,
ionizing radiation, and acid deposition programs.
   The Environmental Monitoring Systems
Laboratory in Cincinnati, Ohio, has as its primary
mission: (a) conducts research in the development,
evaluation, and standardization of chemical and
biological methods for environmental
assessments; (b) conducts research for detecting,
identifying and quantifying microbial pathogens
found in environmental media; and (c) provides
                               124

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ORD Organizational Descriptions
                     technical assistance to the program office and
                     regions for conducting bioassessments of aquatic
                     systems; (d) provides quality assurance in support
                     of the wastewater, and related solid wastes,
                     Superfund, and toxics program.
                       The Atmospheric Research and Exposure
                     Assessment Laboratory in Research Triangle Park,
                     North Carolina, conducts intramural and
                     extramural research programs through laboratory
                     and field research in chemical, physical, and
                     biological sciences to: (a) characterize and
                     quantify present and future ambient air pollutant
                     levels and resultant exposures to humans and
                     ecosystems on local, regional, and global scales; (b)
                     develop and validate models to predict changes in
                     air pollution levels and  air pollutant exposures
                     and determine the relationships among the factors
                     affected by predicted and observed changes; (c)
                     determine source-to-receptor relationships
                     relating to ambient air quality and air pollutant
                     exposures, developing predictive models  to be used
                     for assessments of regulatory alternatives derived
                     from these relationships, directly or indirectly;
                     and (d) conduct long-term research in the areas of
                     atmospheric methods, quality assurance, field
                     monitoring, biomarkers, spatial statistics,
                     exposure assessment, human activity patterns,
                     and modeling research.
 Office of
 Health and
 Environmental
 Assessment
The Office of Health and Environmental
Assessment (OHEA) is responsible for assessing
the effects of environmental pollutants in varying
exposure situations on human health and
ecological systems and determining the degree of
risks from these exposures. The risk assessments
performed by OHEA are used by the Agency as the
scientific basis for regulatory and enforcement
decisions. OHEA's responsibilities also include the
development of risk assessment guidelines and
methodologies, and recommendations for new
research efforts that will better support future
EPA risk assessment activities and research that
will reduce the uncertainties in EPA risk
assessment activities.
                               125

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ORD Organizational Descriptions
                       Comprehensive methodologies are prepared for
                     health assessments of both single chemicals and
                     complex mixtures. Technical assistance to various
                     Agency programs and Regional Offices concerning
                     acceptable pollutant levels and dose-response
                     relations is also provided.
                       The Office includes four organizational groups:
                       The Human Health Assessment Group provides
                     state-of-the-art methodology, guidance, and
                     procedures on the health risks associated with
                     suspected cancer-causing agents and the risks
                     associated with chemicals that are suspected of
                     causing detrimental reproductive effects,
                     including mutagenic, teratogenic, and other
                     adverse reproductive outcomes and reduced
                     fertility; assures quality and consistency in the
                     Agency's scientific risk assessments; provides
                     advice on proposed testing requirements for
                     adequate risk assessments; and prepares
                     independent risk assessments.
                       The Exposure Assessment Group provides
                     advice on the exposure characteristics and factors
                     of agents that are suspected of causing
                     detrimental health effects; provides state-of-the-
                     art methodology, guidance, and procedures for
                     exposure determinations; assures quality and
                     consistency in the Agency's exposure assessments,
                     and prepares independent assessments of exposure
                     and recommendations concerning the exposure
                     potential of specific agents.
                       The Environmental Criteria and Assessment
                     Office in Research Triangle Park, North Carolina,
                     is responsible for preparing air quality criteria
                     documents and air pollutant health assessment
                     documents for use in Agency regulatory activities,
                     as well as legislatively required health-related
                     reports.
                       The Environmental Criteria and Assessment
                     Office in Cincinnati, Ohio, prepares  health and
                     hazard assessment documents on water pollution
                     and solid and hazardous wastes and  hazardous air
                     pollutants.
                               126

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ORD Office/Laboratory
Abbreviations
CERI/CIN
ECAO/CIN
ECAO/RTP
EMSL/CIN
EMSL/LV
AREAL/RTP
RSKERL/ADA
ERL/ATH
Center for Environmental Research Information
 Cincinnati, OH 45268
 CML (513) 569-7391
 FTS 8-684-7391

Environmental Criteria and Assessment Office
 Cincinnati, OH 45268
 CML (513) 569-7531
 FTS 8-684-7531

Environmental Criteria and Assessment Office
 Research Triangle Park, NC 27711
 CML (919) 541-4173
 FTS 8-629-4173

Environmental Monitoring Systems Laboratory
 Cincinnati, OH 45268
 CML (513) 569-7301
 FTS 8-684-7301

Environmental Monitoring Systems Laboratory
 P.O. Box 93478
 Las Vegas, NV 89193-3478
 CML (702) 798-2100
 FTS 8-545-2100

Atmospheric Research and Exposure Assessment
Laboratory
 Research Triangle Park, NC 27711
 CML (919) 541-2106
 FTS 8-629-2106

Robert S. Kerr Environmental Research Laboratory
 P.O. Box 1198
 Ada, OK 74820
 CML (405) 332-8800
 FTS 8-743-2224

Environmental Research Laboratory
 College Station Road
 Athens, GA 30613
 CML (404) 546-3134
 FTS 8-250-3134
                             127

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ORD Office/Laboratory
Abbreviations
ERL/COR
ERL/DUL
ERL/GB
ERL/NARR
HERL/RTP
RREL/CIN
AEERL/RTP
OEETD/HQ
Environmental Research Laboratory
  200 SW 35th Street
  Corvallis, OR 97333
  CML (503) 757-4601
  FTS 8-420-4601

Environmental Research Laboratory
  6201 Congdon Boulevard
  Duluth, MN 55804
  CML (218) 727-6692
  FTS 8-780-5550

Environmental Research Laboratory
  Sabine Island
  Gulf Breeze, FL 32561
  CML (904) 934-9200
  FTS 8-228-9200

Environmental Research Laboratory
  South Ferry Road
  Narragansett, RI02882
  CML (401) 782-3000
  FTS 8-838-6000

Health Effects Research Laboratory
  Research Triangle Park, NC 27711
  CML (919) 541-2281
  FTS 8-629-2281

Risk Reduction Engineering Laboratory
  Cincinnati, OH 45268
  CML (513) 569-7418
  FTS 8-684-7418

Air and Energy Engineering Research Laboratory
  Research Triangle Park, NC 27711
  CML (919) 541-2821
  FTS 8-629-2821

Office of Environmental Engineering and
Technology Demonstration
  (RD-681)
  Washington, DC 20460
  (202)382-2600
                             128

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ORD Office/Laboratory
Abbreviations
OEPER/HQ       Office of Environmental Processes and Effects
                 Research
                  (RD-682)
                  Washington, DC 20460
                  (202) 382-5950
OER/HQ
OHEA/HQ
OHR/HQ
OMMSQA/HQ
Office of Exploratory Research
  (RD-675)
  Washington, DC 20460
  (202) 382-5750

Office of Health and Environmental Assessment
  (RD-689)
  Washington, DC 20460
  (202) 382-7315

Office of Health Research
  (RD-683)
  Washington, DC 20460
  (202) 382-5900

Office of Modeling, Monitoring Systems and Quality
Assurance
  (RD-680)
  Washington, DC 20460
  (202) 382-5767
OTTRS/HQ       Office of Technology Transfer and Regulatory
                 Support
                   (H-8105)
                   Washington, DC 20460
                   (202)382-7669
                            129

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ORD Key Contacts

Abbott, Jim
Akland, Gerald
Barnes, H. M.
Bates, Ed
Benforado, Jay
Berry, Michael
Bishop, Fred
Black, Frank
Blaney, Benjamin
Bond, Andrew
Bond, Randall
Bromberg, Steve
Brunner, Carl
Budde, William
Bufalni, Joseph
Burckle, John
Butler, Larry
Callahan, Michael
Calderon, Rebecca
Chapman, Robert
Clark, Robert
Clark, Thomas A.
Telephone
CML (919) 541-3443
FTS 8-629-3443
CML (919) 541-2346
FTS 8-629-2346
CML(919)541-2184
FTS 8-629-2 184
CML(513)569-7774
FTS 8-684-7774
CML (202) 382-7669
FTS 8-382-7669
CML(919)541-4172
FTS 8-629-4172
CML(513)569-7629
FTS 8-684-7629
CML(919)541-3037
FTS 8-629-3037
CML (513) 569-7 406
FTS 8-684-7406
CML (919) 541-4329
FTS 8-629-4329
CML (202) 382-5893
FTS 8-382-5893
CML(919)541-2919
FTS 8-629-2919
CML (513) 569-7655
FTS 8-684-7655
CML (513) 569-7309
FTS 8-569-7309
CML (919) 541-2706
FTS 8-629-2706
CML (513) 569-7506
FTS 8-684-7506
CML (702) 798-21 14
FTS 8-545-21 14
CML (202) 475-8909
FTS 8-475-8909
CML (202) 382-5893
FTS 8-382-5893
CML (919)966-6219
FTS 8-629-62 19
CML(513)569-7201
FTS 8-684-7201
CML (513) 569-7301
FTS 8-684-7301

Clements, John
Convery, John
Cook, Philip M.
Cortesi, Roger
Costa, Charles
Cote, Ila
Craig, AlfredB.
Cupitt, Larry
Daniel, Bernie
Dellarco, Michael
Dempsey, Clyde
DeRosa, Christopher
desRosiers, Paul
Dick, Marshall
Donaldson, William
Dufour, Alfred
Dyer, Robert
Ehrlich.Alan
Farland, William
Farlow, John
Farrell, Joseph
Finkelstein, Pete
Telephone
CML(919)541-2188
FTS 8-629-2 188
CML (513) 569-7601
FTS 8-684-7601
CML (218) 720-5553
FTS 8-780-5553
CML (202) 382-5750
FTS 8-382-5750
CML (702) 798-2305
FTS 8-545-2305
CML (919) 541-3644
FTS 8-629-3644
CML (919) 541-2821
FTS 8-629-2821
CML(919)541-2107
FTS 8-629-2 107
CML (513) 569-7411
FTS 8-684-7411
CML (202) 382-5794
FTS 8-382-5794
CML (513) 569-7504
FTS 8-684-7504
CML (513) 569-7531
FTS 8-684-7531
CML (202) 382-2722
FTS 8-382-2722
CML (202) 382-2583
FTS 8-382-2583
CML (404) 546-3 183
FTS 8-250-3 183
CML (513) 569-7218
FTS 8-684-72 18
CML(919)541-2760
FTS 8-629-2760
CML(202)382-7315
FTS 8-382-7315
CML (202) 382-7315
FTS 8-382-7315
CML(201)321-6635
FTS 8-340-6635
CML (513) 569-7645
FTS 8-684-7645
CML(919)541-2347
FTS 8-629-2347
                 130

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ORD Key Contacts
Foley, Gary


Fowle, Jack


Freeman, Harry


Galli, Alfred


Garman, Jerry


Garrahan, Kevin


Graham, Judith


Grant, Lester


Graves, Robert


Grose, Elaine


Hall, Robert E.


Hangebrauck, R. P.


Hern, Stephen


Hiatt, Michael

Highsmith, Ross


Hill, Ronald D.


Hogsett, William


Hurst, Pei-Fung


James, Steven


Janetos, Anthony


Jaworski, Norbert A.


Jones, Bruce
Telephone

CML (919) 541-2106
    FTS 8-629-2106
CML (919) 541-2479
    FTS 8-629-2479
CML (513) 569-7529
    FTS 8-684-7529
CML (202) 382-2583
    FTS 8-382-2583
CML (202) 382-7667
    FTS 8-382-7667

CML (202) 382-2588
    FTS 8-382-2588
CML (919) 541-0349
    FTS 8-629-0349

CML(919)541-4173
    FTS 8-629-4173
CML (513) 569-7325
    FTS 8-684-7325
CML (919) 541-3844
    FTS 8-629-3844
CML (919) 541-2477
    FTS 8-629-2477
CML(919)541-4134
    FTS 8-629-4134
CML (702) 798-2594
    FTS 8-545-2594

CML (702) 798-2381
    FTS 8-545-2381
CML (919) 541-7828
    FTS 8-629-7828
CML (513) 569-7546
    FTS 8-684-7546
CML (503) 755-4632
    FTS 8-420-4632
CML (513) 569-7585
    FTS 8-684-7585
CML (513) 569-7877
    FTS 8-684-7877
CML (202) 382-5791
    FTS 8-382-5791
CML (401) 782-3000
    FTS 8-838-6000
CML (702) 798-2671
    FTS 8-545-2671
Jones, Julian


Kapustka, Lawrence


Keeler, George


Keith, William


Klauder, David


Klee.Al


Kleffman, David


Knapp, Kenneth


Koglin, Eric


Kreissl, James


Krishnan, Bala


Kutz, Frederick W.


Kuehl, Douglas W.


Landreth, Robert E.


Laveille.WillC.


Lazorchak, James


Lee, Henry II


Leach, Lowell


Levinson, Barbara


Lewtas, Joellen


Lichtenberg, James


Lindsey, Alfred
Telephone

CML (919) 541-2489
    FTS 8-629-2489
CML (503) 757-4606
    FTS 8-420-4606
CML (405) 332-8800
    FTS 8-743-2212
CML (202) 382-5776
    FTS 8-382-5776
CMS (202) 382-7667
    FTS 8-382-7667
CML (513) 569-7493
    FTS 8-684-7493
CML (202) 382-5893
    FTS 8-382-5893

CML (919) 541-3085
    FTS 8-629-3085
CML (702) 798-2237
    FTS 8-545-2237
CML (513) 569-7611
    FTS 8-684-7611
CML (202) 382-2613
    FTS 8-382-2613
CML (202) 382-5776
    FTS 8-382-5776
CML(218)720-5511
    FTS 8-780-5511

CML (513) 569-7871
    FTS 8-684-7871
CML (202) 382-5990
    FTS 8-382-5990
CML(513)569-8114
    FTS 8-684-8114
CML (503) 867-4042
CML (405) 332-8800
    FTS 8-743-2333
CML (202) 382-5983
    FTS 8-382-5983
CML (919) 541-3849
    FTS 8-629-3849
CML (513) 569-7306
    FTS 8-684-7306
CML (202) 382-4073
    FTS 8-382-4073
                                     131

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ORD Key Contacts

Linthurst, Rick
Lykins, Ben
Maxwell, Michael
McCarthy, Bill
McElroy, James L.
McKee, Gerald
McKinnon, Hugh
McNabb, James F.
Meier, Eugene
Menzer, Robert
Messer.Jay
Miller, Thomas
Mitchell, WUliam
Mitchum, R. K.
Moore, Martha
Moore, Michael
Mulkey, Lee A.
Mullin, Cynthia
Murphy, Thomas A.
Nalesnik, Richard P.
Oberacker, Donald
Olexsey, Robert
Telephone
CML (202) 382-5767
FTS 8-382-5767
CML (513) 569-7460
FTS 8-684-7460
CML (919) 541-3091
FTS 8-629-3091
CML (202) 382-2605
FTS 8-382-2605
CML (702) 798-2361
FTS 8-545-2361
CML (513) 569-7303
FTS 8-684-7303
CML (202) 382-5898
FTS 8-382-5898
CML (405) 332-8800
FTS 8-743-2216
CML (702) 798-2237
FTS 8-545-2237
CML (904) 934-9200
FTS 8-228-90 11
CML (919) 541-0150
FTS 8-629-0 150
CML (202) 382-5893
FTS 8-382-5893
CML (919) 541 -2769
FTS 8-629- 2769
CML (702) 798-2103
FTS 8-545-2103
CML(919) 541-3933
FTS 8-629-3933
CML (202) 382-7671
FTS 8-382-7671
CML (404) 546-3546
FTS 8-250-3546
CML (513) 569-7523
FTS 8-684-7523
CML (503) 757-4601
FTS 8-420-4601
CML (202) 382-2583
FTS 8-382-2583
CML (513) 569-7510
FTS 8-684-75 10
CML (513) 569-7861
FTS 8-684-7861

Olson, Richard
Oppelt, Timothy.
Pahl, Dale
Parish, Rod
Patton, Dorothy
Paur, Dick
Pearson, Gareth
Peirano, Bruce
Perlin, Susan
Pesch, Gerald G.
Pheiffer, Tom
Pitchford, Marc
Plyler, Everett
Preston, Walter
Preuss, Peter
Pritchard, Hap
Reiter, Larry
Rhodes, William
Ringold, Paul
Rogers, Charles
Rogers, John
Rossman, Lewis
Telephone
CML (503) 757-4666
FTS 8-420-4666
CML (513) 569-7896
FTS 8-684-7896
CML (919)541-1851
FTS 8-629-1851
CML (904) 934-9221
FTS 8-228-9221
CML (202) 475-6743
FTS 8-475-6743
CML(919)541-3131
FTS 8-629-3 131
CML (702) 798-2203
FTS 8-545-2203
CML (513) 569-7540
FTS 8-684-7540
CML (202) 382-5893
FTS 8-382-5893
CML (401 (782-3000
FTS 8-838-6007
CML (202) 382-5776
FTS 8-382-5776
CML (702) 798-2363
FTS 8-545-2363
CML (919) 541-2918
FTS 8-629-2918
CML (202) 382-7445
FTS 8-382-7445
CML (202) 382-7669
FTS 8-382-7669
CML (904) 934-9260
FTS 8-228-9260
CML (919) 541-2281
FTS 8-629-2281
CML (919) 541-2853
FTS 8-629-2853
CML (202) 382-5609
FTS 8-382-5609
CML (513) 569-7757
FTS 8-684-7757
CML (404) 543-3 103
FTS 8- 250-3 103
CML (513) 569-7603
FTS 8-684-7603
                 132

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ORD Key Contacts

Royer, Michael
Russo, Rosemarie, C.
Saint, Chris
Sala, Ken
Sanville, William
Scalf, M. Richard
Schiermeier, Francis
Schonbrod, Robert
Schuda, Laurie
Sexton, Ken
Shreffler.Jack
Sigmon, John T.
Snelling, Robert
Sommers, Kevin
Sorg, Tom
Spence, John J.
Stevens, A]
Tang, Don
Thomas, Nelson
Tingey, Dave
Tucker, W. Gene
Veith, Oilman
Telephone
CML (201) 321-6633
FTS 8-340-6633
CML (404) 546-3134
FTS 8-250-3 134
CML (202) 382-5776
FTS 8-382-5776
CML (202) 382-5776
FTS 8-382-5776
CML (218) 720-5723
FTS 8-780-5723
CML (405) 332-8800
FTS 8 743-2308
CML(919)541-4541
FTS 8-629-4541
CML (702) 798-2100
FTS 8-545-2229
CML (202) 382-5776
FTS 8-382-5776
CML (202) 382-5900
FTS 8-382-5900
CML(919)541-2194
FTS 8-629-2194
CML (202) 382-5738
FTS 8-382-5738
CML (702) 798-2525
FTS 8-545-2525
CML (904) 934-9244
FTS 8-228-9244
CML (513) 569-7370
FTS 8-684-7370
CML (919) 541-2649
FTS 8-629-2649
CML (513) 569-7342
FTS 8-684-7342
CML (202) 382-2621
FTS 8-382-2621
CML (218) 720-5702
FTS 8-780-5702
CML (503) 757-4621
FTS 8-420-4621
CML (919) 541-2746
FTS 8-629-2746
CML (2 18) 720-5500
FTS 8-780-5500

Vickery, James
Walker, Henry A.
Weber, Cornelius
Wentworth, Nancy
Wiles, Carlton
Wilhour, Raymond
Williams, Bill A.
Williams, Llew
Williams, Sam
Wilmoth, Roger
Wilson, William
Winter, John
Worlund, John
Worrest, Robert
Wu, Chieh
Zenick, Harold






Telephone
CML (919) 541-2184
FTS 8-629-2 184
CML (401) 782-3134
FTS 8-838-6134
CML (513) 527-8350
FTS 8-778-8350
CML (202) 382-5763
FTS 8-382-5763
CML (513) 569-7795
FTS 8-684-7795
CML (904) 934-9200
FTS 8-228-9213
CML (503) 757-4679
FTS 8-420-4679
CML (702) 798-2138
FTS 8-545-2138
CML (202) 382-5967
FTS 8-382-5967
CML (513) 569-7509
FTS 8-684-7509
CML (919) 541-2551
FTS 8-629-2551
CML (513) 569-7325
FTS 8-684-7325
CML (702) 798-2656
FTS 8-545-2656
CML (202) 382-5981
FTS 8-382-5981
CML (202) 382-5977
FTS 8-382-5977
CML (919) 541-2281
FTS 8-629-2281






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ORD Regional Contacts
The Office of Research and Development's Regional Operations Staff is
responsible for planning, coordinating, and reviewing programs that
provide inter-communication and assistance on all matters of mutual
interest and/or responsibility of the Agency's Regional Offices and the
Office of Research and Development.
Director, David Klauder
  Regional Operations Staff (RD-672)
  Washington, DC 20460

Regional Liaison Officer, Glenn Williams
Regional Operations Staff
Washington, DC 20460

Coordinator, Regional Scientist
 Program, Vacant
Washington, DC 20460

Coordinator, Regional Superfund
  Technical Liaison Program
Jerry Garman
Washington, DC 20460

ORD/OTTRS Regional Scientists

Gregory A. Kew, Region I
Boston, MA 02203

John Montanari, Region IV
Atlanta, GA 30365

Louis J. Blume, Region V
Chicago, IL 60604

H. George Keeler, Region VI
Dallas, TX 75270

Dermont Bouchard, Region VII
Kansas, City, KS 66101

Winona Victery, Region IX
San Francisco, CA 94103
       Telephone

CML (202) 382-7667
    FTS 8-382-7667
CML (202) 382-7667
    FTS 8-382-7667
CML (202) 382-7667
    FTS 8-382-7667

CML (202) 382-7667
   FTS: 8-382-7667
CML (617) 565-3715
    FTS 8-853-3715

CML (404) 347-7109
    FTS 8-257-7109

CML (312) 353-2000
    FTS 8-353-2000

CML (214) 655-2252
    FTS 8-255-2252

CML (913) 551-7519
    FTS 8-276-7519

CML (415) 556-6466
    FTS 8-556-6466
                              134

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EPA Regional Offices
Region 1    Environmental Protection Agency
           Room 2203
           John F. Kennedy Federal Building
           Boston, Massachusetts 02203
           CML (617) 565-3424
           FTS 8-835-3424

Region 2    Environmental Protection Agency
           Room 900
           26 Federal Plaza
           New York, New York 10278
           (212) 264-2515
           FTS 8-264-2515

Region 3    Environmental Protection Agency
           841 Chestnut St.
           Philadelphia, Pennsylvania 19107
           (215)597-9370
           FTS 8-597-9370
Region 4    Environmental Protection Agency
           345 Courtland Street, N.E.
           Atlanta, Georgia 30365
           CML (404) 347-3004
           FTS 8-257-3004
Region 5    Environmental Protection Agency
           230 S. Dearborn
           Chicago, Illinois 60604
           (312) 353-2072
           FTS 8-353-2072
Region 6    Environmental Protection Agency
           1445 Ross Ave.
           12th Floor, Suite 1200
           Dallas, Texas 75202
           CML (214) 655-2200
           FTS 8-255-2200
Connecticut
Maine
Massachusetts
New Hampshire
Rhode Island
Vermont

New Jersey
New York
Puerto Rico
Virgin Islands
Delaware
District of Columbia
Maryland
Pennsylvania
West Virginia
Virginia

Alabama
Florida
Georgia
Kentucky
Mississippi
North Carolina
South Carolina
Tennessee

Illinois
Indiana
Michigan
Minnesota
Ohio
Wisconsin

Arkansas
Louisiana
New Mexico
Oklahoma
Texas
                              135

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EPA Regional Offices
Region 7    Environmental Protection Agency
           726 Minnesota Avenue
           Kansas City, Kansas 66101
           CML (913) 551-7003
           FTS 8-276-7003

Region 8    Environmental Protection Agency
           999 18th Street
           Suite 500
           Denver, Colorado 80202-2405
           CML (303) 293-1692
           FTS 8-330-1692

Region 9    Environmental Protection Agency
           215 Fremont Street
           San Francisco, California 94105
           CML (415) 556-6387
           FTS 8-556-6387
Region 10   Environmental Protection Agency
           1200 6th Avenue
           Seattle, Washington 98101
           CML (206) 442-1466
           FTS 8-399-1466
Iowa
Kansas
Missouri
Nebraska
Colorado
Montana
North Dakota
South Dakota
Utah
Wyoming

Arizona
California
Hawaii
Nevada
Guam
American Samoa

Alaska
Idaho
Washington
Oregon
          *U.S. GOVERNMENT PRINTING OFFICE: 1990—726-130/D09636
                              136

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