EPA/600/9-91/025
                                  September 1991
            FY-1992
       EPA Research
       Program Guide

October 1, 1991—September 30, 1992
               U.S. Environmental Protection Agency
               Regon 5, Library (PL-12J)
               7? West Jackson Boulevard, 12th Floor
               Chicago, IL  60604-3590
       Office of Research and Development
      U.S. Environmental Protection Agency
          Washington, DC 20460
                              Printed on Recycled Paper

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Notice
The program descriptions and resource estimates included in this document reflect the
latest detailed information available at time of publication. Time will change some of
this information. In addition, the resource figures have been rounded off and some
smaller programs omitted. For the latest information, you may want to contact the
individual listed.

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Contents
Introduction	1

How to Use the Program Guide	2

Air	3
  Hazardous Air Pollutant Regulatory Activities	3
  Mobile Source Pollutant Regulatory Activities	...8
  Mobile Sources	10
  National Ambient Air Quality Standards (NAAQS)	.11
  New Source Performance Standards and State Implementation Plans	15
  Indoor Air Pollution Activities	18
  Indoor Air	20
  Global Change Research and Stratospheric Ozone Research	21
  Global Climate Change	24
  Clean Air Act Amendments	24
  Health Effects Institute	25
  Deposition Monitoring and Understanding Atmospheric Processes	26
  Energy	27

Drinking Water	29
  Health Effects of Drinking  Water Contaminants	29
  Ground Water Research	30
  Ground Water	30
  Drinking Water Technology	31

Water Quality	34
  Water Quality Based Approach/Permitting	34
  Industrial Wastewater Treatment Technology	35
  Wastewater Treatment Technology	36
  Marine, Estuaries, and Lakes	38

Hazardous Waste	40
  Alternate Technologies	40
  Incineration	41
  Land Disposal	42
  Pollution Prevention	43
  Municipal Solid Waste	43
  Municipal Solid Waste Monitoring	45
  Waste Characterization	46
  Quality Assurance	47
  Releases	48
  Waste Identification	50
  Development of Techniques and Procedures to Prevent and
    Contain Oil Spills	51
  Develop Data to Support Treatment, Storage, Disposal Regulations	52
  Technology Transfer	52
  Oil Spills Research	53

                               iii

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 Contents  (continued)
Toxic Substances	54
  Biotechnology	54
  Biotechnology/Microbial and Biochemical Pest Control Agents	55
  Ecology: Ecotoxicity and Risk Assessment	57
  Ecology: Transport/Fate/Field Validation	58
  Exposure Monitoring	59
  Health: Markers, Dosimetry, and Extrapolation	59
  Special Human Data Needs	60
  Structure Activity Relationships	60
  Emergency Planning and Community Right to Know	61
  Support for Toxic Substances Control Act(TSCA)	63
  Engineering	63
  Test Method Development	65
  Asbestos	66

Pesticides	67
  Biotechnology/Microbial and Biochemical Pest Control Agents	67
  Support for Federal Insecticide, Fungicide and Rodenticide Act
    (FIFRA) Activities	68
  Ecology: Ecotoxicity and Risk Assessment	69
  Ecology: Transport/Fate/Field Validation	70
  Engineering	71
  Exposure Monitoring	71
  Health: Markers, Dosimetry, and Extrapolation	72
  Test Method Development	72

Multimedia—Core	74
  National Health and Nutrition Examination Survey (NHANES-in)	74
  Research to Improve Health Risk Assessment (RIHRA) (Health)	75
  Exploratory Research Grants	75
  Exploratory Research Centers	76
  Pollution Prevention	77
  Socioeconomic Research	78
  Total Human Exposure	79

Multimedia	81
  China Program	81
  Harvard Study	81
  Consistent Risk Assessment	81
  Lead Abatement	82
  Development, Validation, and Standardization of Analytical Methods
    in Support of Regional Programs	82
  Reducing Uncertainty in Ecological Risk Assessment	83
  Ecological Status and Trends	84
  Visiting Scientists Program	85
  Small Business Innovation Research (SBIR) Program	86
  Arctic Studies	86

                              iv

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Contents (continued)
  Manage the Mandatory Quality Assurance Program	87

Radiation	90
  Off-Site Monitoring Program	90
  Scientific Support for Radon Program	90
  Electric and Magnetic Field Research (EMF)	91

Superfund	93
  Provide Techniques and Procedures for Site and Situation Assessment	93
  Clean-up of Uncontrolled Hazardous Waste Sites Requires Technologies
    for Response and Remedial Action, for Protecting the Personnel Involved
    and for Supporting Enforcement Actions	93
  Provide Quality Assurance—Superfund Program Requirements	94
  Provide Technical Support to Enforcement, Program, and Regions	95
  Provide Technical Support to Enforcement, Program, and Regional Offices	96
  Hazardous  Substances Health Effects/Risk Assessment and Detection Research	97
  Health Effects Assessments	98
  Superfund Reportable Quantity Regulatory Efforts	98
  Field Screening Techniques for Assessment and Evaluation	99
  Monitoring Technology, Development, and Demonstration	100
  Hazardous  Substance Research Centers Program	101
  Small Business Innovation Research (SBIR) Program—Superfund	101
  Superfund Research Grants	102
  Evaluate Technologies to  Manage Uncontrolled Waste Sites	102

Overview	104

Organization  Chart	106

ORD Organization	107

ORD Organizational Descriptions	113

ORD Office/Laboratory Abbreviations	128

ORD Key Contacts	131

ORD Regional Contacts	138

EPA Regional Offices	140

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 Introduction
    The free and open exchange of knowledge both stimulates and provides quality
control for the progress of science. This report provides information on the research
which EPA is planning for this fiscal year, on how much we intend to spend on each
program area, and on whom to contact for further details. More than 60 percent of our
research budget will be spent through extramural contracts, grants, and cooperative
agreements with organizations outside of EPA's laboratories.
    It is our intent to increase the efficiency and effectiveness of this research by
placing great emphasis upon open competition for extramural support We hope that
the information in this report will stimulate qualified parties and make their capabili-
ties known to our research managers so that we all might gain from sharing experi-
ence and expertise. Please feel free to contact any of the parties listed in this report.

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How to  Use the Program  Guide	


    The following descriptions of the research program of the Office of Research and
Development (ORD) are organized first by media such as air, water, hazardous wastes,
etc. These categories are further broken down into research foci such as scientific
assessment, monitoring and quality assurance, health effects, environmental processes,
and engineering technology. Each description is a very broad summary of the research
being done, where that research is being done, whom to contact for more information
about the program, and both the approximate total funding for that area and the
percentage of total funding which is reserved by EPA for in-house research. Funding
which is not reserved for in-house research is spent through extramural contracts,
grants and cooperative agreements.
    For each program description, one or more contacts are listed along with the
major research areas to be pursued. For further information, you may call the contacts.
Their commercial and Federal (FTS) telephone numbers are listed in a separate section
near the end of this report. Where two or more research laboratories are listed, please
turn to the "ORD Organization Descriptions" section of this report for descriptions of
the major mission and functions of each.
    Some of the research funded for this fiscal year will be done  in-house by EPA's
laboratories. The rest will be accomplished extramurally. Proposals for funds for
research in areas of interest to the agency  are welcomed and are considered on a
competitive basis. To receive information regarding application procedures for extra-
mural funds, please contact the person indicated in the area of specific interest to you.
In addition, approximately fifteen percent of EPA's research budget is used  to support
long-term exploratory research. Information regarding funds for exploratory  research
grants can be obtained from the:

    Research  Grants Program
    Office of Exploratory Research (RD-675)
    USEPA
    Washington, DC 20460
    (202)  260-5750

    Finally, for further information regarding Office of Research and Development
research publications (600/series) or for additional copies of this report, please contact

    Center for Environmental Research Information
    USEPA
    26 W. Martin Luther King Drive
    Cincinnati, OH 45268
    CML (513)  569-7562
    FTS 8-684-7562

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Air
Environmental
Engineering and
Technology
Demonstration
Hazardous Air Pollutant Regulatory
Activities

    The 1990 Clean Air Act Amendments (CAAA)
require EPA to establish emission standards for source
categories of the 189 air toxics listed under Title HI of
the 1990 CAAA. These emission standards must be
based on Maximum Achievable Control Technology
(MACT) or Generally Available Control Technology
(GACT) for  some area sources. In order to support this
revamped air toxics regulatory approach, ORD is
conducting research on innovative air toxic control
approaches which will be applicable to source catego-
ries, including area sources, which emit one or more of
the 189 air toxics. The focus of the innovative control
work is on development of the corona destruction
process which at the bench and small pilot scale has
shown great  promise as a cost effective technique for
controlling low concentration  streams of several air
toxics. ORD/Office of Environmental Engineering and
Technology Demonstration (OEETD) is working
cooperatively with industry and the military to demon-
strate the performance of the corona reactor at large
pilot scale, possibly 1000 cfm. This larger scale demo
is supported  by fundamental in-house corona destruc-
tion research. Techniques to prevent air toxic emis-
sions are also under investigation as part of the
Administrator's 2% Pollution  Prevention Set-Aside
Program. Source reduction approaches for air toxic
emissions from auto  body refinishing and wood
furniture coating operations (both of these operations
emit several  of the 189  air toxics) are being demon-
strated. These demonstrations are expected to facilitate
market acceptance of these new environmentally
benign coating approaches. Wood stoves (a major non-
point source  of air toxics) research is improving the
existing EPA certification test and testing an ORD-
developed secondary combustion wood stove to assess
its performance in the field.  ORD is also attempting
to improve the performance of existing in-use air
toxics control technologies for point and area sources
by determining the extent to which these technologies
are  operating below design specifications and develop-
ing enhanced operation and maintenance approaches to
prevent and control the resulting excess emissions. The
initial emphasis of the control effectiveness program is
on control devices and techniques used in the coatings

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Air
                            industry. Technical assistance to state and local
                            agencies is expanding to address the expected increase
                            in requests for technical information due to the 1990
                            CAAA. This assistance is provided  through the Control
                            Technology Center (CTC) which is  jointly funded by
                            ORD and  OAQPS to provide technical information on
                            air toxic control technologies via the CTC HOTLINE
                            and to  conduct engineering evaluations which provide
                            data on emissions and control options for sources
                            where this information is not readily available. Finally,
                            methods to improve emissions estimates are being
                            developed for specific air toxic source categories. This
                            emissions  methodology research supports development
                            of the national area source strategy  mandated under
                            section  112(K) of the 1990 CAAA and the Great
                            Lakes study.

                            Office  or                         Total      Percent
                            Laboratory       Contact     Funds($K)  In-House

                            AEERL/RTP    Wade Ponder     3,992.9    40
                            OEETD/HQ     Marshall Dick     250.0    75
                            Hazardous Air Pollutant Regulatory
                            Activities

Health Effects               The Health research program for Hazardous Air
                            Pollutants (HAPs) has three goals: (1) to develop and
                            validate techniques to evaluate the toxic effects of
                            HAPs, (2) to produce dose-response data on the toxic
                            effects of HAPs, and (3) to develop methods which
                            improve our ability to use lexicological data in
                            performing risk assessments.
                                Research is conducted on effects associated with
                            specific chemicals, chemical classes and complex
                            mixtures.
                                More broadly, there is a need to evaluate whether
                            prolonged exposure to ambient levels of HAPs pose a
                            significant health risk. Primary research approaches are
                            animal toxicology and dosimetry  studies. EPA re-
                            searchers will develop methods to provide data on the
                            genetic, developmental, and neurotoxic effects of
                            HAPs. Emphasis of this research  will be on the toxic
                            components of gaseous-aerosol complex mixtures and
                            source emissions. Emphasis is also shifting towards
                            research that will resolve generic  extrapolation issues,
                                    4

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Air
                            such as route-to-route extrapolation, and extrapolation
                            across dose concentrations and durations.
                                Dose-response data on the mutagenic and carcino-
                            genic activity and noncancer endpoints, including
                            neurotoxicity, physiological, and pulmonary health
                            effects of potential HAPs will be generated. HAPs will
                            be selected for study in order to support the require-
                            ments of Title IH of the 1990 Clean Air Act Amend-
                            ments and to meet needs identified by the Office of
                            Air Quality, Planning, and Standards (OAQPS). The
                            effects of selected chemicals suspected of being
                            hazardous to the nervous system will be studied. Dose-
                            exposure research will provide quantitative information
                            on the relationship between dose (body burden) and
                            human exposure to toxic pollutants.
                            Office or
                            Laboratory

                            HERL/RTP
                            OHR/HQ
                 Contact

               Ila Cote
               Susan Perlin
  Total     Percent
Funds($K) In-House
   3,588.9
72
Modeling,
Monitoring Systems
and Quality
Assurance
Hazardous Air Pollutant Regulatory
Activities

    The need for technology to monitor non-criteria
contaminants at the regional, state, and local levels
continues. Broad-based stationary source screening
methods, generic methods and specific methods for
hazardous pollutants with emphasis on source emission
monitoring in support of Maximum Achievable Control
Technology (MACT) regulation development as
specified in the 1990 CAAA are ongoing. Stationary
source methods wiU be evaluated and validated. In
addition, certain advanced ambient methods will be
evaluated, including cryogenic preconcentrations, gas
chromatography and Fourier Transform Infrared
(FTIR) spectrometry.
    To support quality assurance needs within the
program, reference samples will be developed and
maintained, guidelines for procedures will be devel-
oped, and laboratory audits  will be performed.
    A major ORD field program, the Integrated Air
Cancer Projects (IACP), will continue to study the
origins and chemical composition of individual species

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Air
                            of toxics, mutagenic or carcinogenic pollutants which
                            are present in ambient air.
                               Laboratory studies are underway to determine
                            atmospheric reaction rates and transformation products
                            of HAPs. These studies will describe the formation,
                            removal, and fate of air toxics in complex atmospheric
                            mixtures found in urban air. As part of the IACP, the
                            program is conducting an ambient air monitoring study
                            in an urban location to quantify the sources of carcino-
                            gens in ambient air. In addition, the program will
                            develop methods for characterizing area-wide source
                            emissions of toxics.     ,
                               Also, research studies will examine the atmo-
                            spheric chemical and physical processes that are
                            important in producing mutagenic compounds in the
                            atmosphere.  The information obtained from this
                            program is used for preparing health assessment
                            documents to determine if chemicals in the atmosphere
                            present a hazard.

                            Office or                        Total     Percent
                            Laboratory      Contact      Funds($K) In-House

                            AREAL/RTP   John Clements    5,619       49
                                           Larry Cupitt
                            OMMSQA/HQ  Dwight Hlustick
                            Hazardous Air Pollutant (HAP) Regulatory
                            Activities
Scientific                     Th£ hazardous air pollutant scientific assessment
Accoccmont             program of the Office of Health and Environmental
Assessment             Assessment (OHEA) has four major elements: (1)
                            health assessments, (2) research to improve methodolo-
                            gies for these assessments,  (3) technological/informa-
                            tion transfer, and (4) expert consultation to the Office
                            of Air and Radiation (OAR) on all the above elements.
                            During FY92, major emphasis will be placed on
                            implementation of programs that are responsive to new
                            requirements of the CAAA.  Health assessment
                            activities will focus on the list of 189 air-toxics in the
                            CAAA and OAR information needs relative to their
                            decisions on negligible risk, residual risk, designation
                            of lesser quantity cut-offs, ranking of hazard for
                            modifications, and source category designation. Cancer
                            unit risks will be developed  for those listed air toxics

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Air
                             that have not already been evaluated.  Chronic
                             inhalation reference concentrations (RfC) will be
                             developed for non-cancer effects.  As a methodology
                             for acute RfCs becomes available from the research
                             program, acute RfCs will be developed.  Draft RfCs
                             are submitted to the EPA-wide RfD/RfC Work Group,
                             co-chaired by OHEA. After verification or determina-
                             tion that the data base is inadequate for an RfC, the
                             appropriate information is entered onto the Integrated
                             Risk Information System (IRIS.)  Those listed
                             chemicals having data bases inadequate to meet the
                             criteria for RfC development will be identified.
                             OHEA provides support to the Office of Air Quality
                             Planning and Standards (OAQPS) in identifying risks
                             for these chemicals. Another aspect  of the program is
                             to complete health assessment documents and other
                             documents not processed in FY-91.
                                  A research program is being conducted to
                             improve methodologies for risk assessment of air
                             toxics. The focus is on non-cancer health effects and
                             the RfC  methodology.  This research is designed to
                             enhance the scientific foundation of assumptions
                             inherent in all assessments and to increase the utility
                             of the assessments to the program offices. This
                             involves: (1) improving the quantitative basis for
                             uncertainty assumptions in the chronic RfC method so
                             that, ultimately, some key assumptions can be
                             replaced with actual values, (2) developing an acute
                             RfC method, and (3) developing procedures to assess
                             risks above the RfC.  Based on results from this
                             research, the RfC methodology will  be revised and
                             subjected to expert peer review  and  Agency review
                             prior to completion and EPA-wide implementation.
                                 OHEA, jointly with OAQPS, operates the Air
                             Risk Information Support Center (Air RISC).  This
                             Center provides information on  health risks of air
                             toxics  to state and local air pollution agencies as well
                             as to EPA Regions. Rapid  response is achieved via a
                             hot-line operation. Numerous types of technical
                             guidance are also provided.  OHEA also acts as
                             technical consultant to OAR on air toxics health
                             issues by providing expert review on listing/delisting
                             decisions.

                             Office or                         Total     Percent
                             Laboratory       Contact      Funds($K)In-House

                             ECAO/RTP     Lester Grant       4106.3     48
                                    7

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Air
Health Effects
Modeling,
Monitoring Systems
and Quality
Assurance
Mobile Source Pollutant Regulatory
Activities

    The health effects research program for mobile
sources provides health effects data for selected
emissions and transformation products associated with
motor vehicles. One goal of the research conducted by
the Health Effects Research Laboratory is to develop
methods and data that can be used to characterize the
risk of mobile source emissions  as a component of the
total human exposure to carcinogens and mutagens.
Methods are being developed to apportion the potential
cancer risk from alternative engine and fuel types. The
work includes the assessment of DNA adducts as
biomarkers of exposure, dosimetry, or cancer risk from
mobile source emissions in comparative mutagenesis
and tumorigenesis bioassay systems in vitro and in
vivo. The work also includes an examination of the
impact of alternative fuels and their emissions on
human health, with the focus on pharmacokinetics and
mutagenic activity of methanol exposure. Work
continues on the evaluation of the impact of atmo-
spheric transformation on the carcinogenic potential of
mobile source emissions.
                            Office or
                            Laboratory

                            HERL/RTP
                            OHR/HQ
                 Contact

               Ila Cote
               Susan Perlin
  Total     Percent
Funds($K) In-House
    408.3
34'
Mobile Source Pollutant Regulatory
Activities

    The major effort in this program is to characterize
the emissions from motor vehicles using both tradi-
tional fuels as well as alternative fuels, such as
methanol, compressed natural gas or reformulated
gasoline. Laboratory studies of the impact of ambient
temperature on the emission rates of regulated and
unregulated pollutants from light duty motor vehicles
will continue. Emphasis will be directed to the compo-
sition of organic emissions. Studies of the relationship
between fuel composition, including gasoline and
gasoline-alcohol blends, and the composition and rate
of tailpipe, evaporative, and refueling emissions will
continue. Other programs will emphasize the develop-
                                   8

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Air
                             ment of analytical procedures suitable for real-time
                             measurement of motor vehicle emissions. Procedures
                             for determination of the operating condition of motor
                             vehicle emission control devices will be evaluated.
                             Programs for examination, development, and improve-
                             ment of procedures for apportionment of observed
                             ambient pollution to motor vehicles will be conducted.
                                 Studies will also be conducted to characterize
                             organic emissions from motor vehicles under widely
                             variant operating conditions, i.e., temperature, eleva-
                             tion, speed, and fuels,  including evaporative hydrocar-
                             bon emissions from refueling, running losses, and long
                             term standing. Emission rates of formaldehyde,
                             benzene, paraffins, and other organic compounds of
                             interest will be determined.
                                 Research will also focus on developing methodol-
                             ogy for determining exposures of the population to
                             mobile source pollutants.  A general methodology  has
                             been developed for measuring and modeling the
                             exposures of the population to carbon monoxide, and
                             this methodology has been successfully field tested.
                             Future research will extend this methodology to other
                             locations and, where possible, to other mobile source
                             air pollutants. Detailed analyses of human exposure
                             field data collected in  selected highway microenviron-
                             ments will be undertaken to develop improved com-
                             muter exposure models incorporating traffic  variables
                             (roadway type, traffic count, trip time, and seasonal
                             characteristics). Data on human  activity patterns and
                             time budgets will be further evaluated for use in
                             exposure models. Improved models of human activity
                             patterns and microenvironmental concentrations will be
                             developed and field tested. The  Simulation of Human
                             Activities and Pollutant Exposure (SHAPE) model will
                             be modified and validated using field data from
                             another urban area. Additional testing of basic assump-
                             tions incorporated in the NAAQS Exposure Model
                             (NEM) wiU be undertaken. The purpose of the research
                             will be to improve the accuracy and reliability of  the
                             Agency's exposure assessment methodology for mobile
                             source pollutants.

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Air
                            Office or
                            Laboratory

                            AREAL/RTP
                            OMMSQA/HQ
                                 Total     Percent
                 Contact     Funds($K) In-House
                Ken Knapp
                Dale Pahl
                Frank Black
                Dwight Hlustick
3,010
38
Scientific
Assessment
Mobile Sources

    OHEA is providing management of the ORD
Alternative Fuels Research Program and scientific
assessments of major issues related to EPA's develop-
ment of policies and regulations on alternative fuels.
OHEA is coordinating ORD activities to develop a
Research Strategy that describes research needed to
quantitatively assess the human health and ecosystem
effects and greenhouse gas emissions related to
production, storage, and use of alternative fuels  (e.g.
methanol, ethanol, compressed natural gas, and
reformulated gasolines) compared to conventional
gasoline and diesel fuels. This strategy is intended to
provide broad guidance to development of targeted
research programs within ORD as well as other
scientific institutions which have an interest in alterna-
tive fuels. The strategy will be reviewed by the
Scientific Advisory Board and by the public before the
final document is developed.
    As part of the scientific assessment portion  of
ORD's Alternative Fuels Program, OHEA will develop
assessments of key health and ecosystem issues  and
provide overall co-ordination of the program within
and outside EPA. This will entail the development of
major health and ecosystem assessments of the alterna-
tive fuels and conventional fuels. These documents will
be subjected to expert scientific review at workshops,
as well as public and Scientific Advisory Board
reviews. Assessments of additional topics (i.e., acciden-
tal ingestion of alternative fuels by children, the health
impacts of alterations in ozone  levels resulting from
fuel switching, and predicted occurrences of large
accidental spills of alternative fuels into aquatic
systems) will also be developed, along with interpreta-
tive reports of findings from the ORD research
program. This assessment program began in FY-91
with the initiation of a methanol assessment and the
                                    10

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 Air
                           completion of a Million Metric Tons (MMT) assess-
                           ment In FY92 the emphasis will be on: (1) completing
                           an assessment of the health effects of diesel  emissions,
                           including the development of a cancer unit risk and (2)
                           initiating a revaluation of the cancer unit risks of
                           benzene and 1,3-butadiene.
                               Another key element is to coordinate the research
                           program with all interested scientific institutions (i.e.,
                           federal, private, academic and international). As one
                           step in this process, OHEA will hold an international
                           meeting on alternative fuels in FY92, at which these
                           institutions will be invited to describe their programs
                           and recent research results, thereby substantially
                           improving communication. A proceedings of the
                           meeting will be developed.

                           Office or                       Total     Percent
                           Laboratory      Contact      Funds($K) In-House
                            ECAO/RTP     Judith Graham
                                 273.4
54
Modeling,
Monitoring Systems
and Quality
Assurance
National Ambient Air Quality Standards
(NAAQS)

    The purpose of this program is to provide scien-
tific information on atmospheric processes and moni-
toring methodologies to support the Agency's
regulatory program on National Ambient Air Quality
Standards (NAAQS). The current program will focus
on inhalable paniculate matter, fine particles and acid
aerosols research, and visibility.
    Under the Monitoring Systems and Quality
Assurance portion of this program, improved air
pollution monitoring methods are being developed to
help determine air quality trends, support compliance
with standards, and meet enforcement needs. The data
from these methods are often used as the basis for
regulatory action. The areas investigated include
ambient methods development, quality assurance
guidelines and audit materials preparation as well as
studies of the formation, characterization and control of
acid aerosols and visibility.
    Ambient methods development focuses on measur-
ing paniculate matter in support of anticipated changes
to the NAAQS as well as the development of im-
proved methodologies for acid aerosol and visibility
measurements.
        11

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                                The visibility research program is addressing the
                            analysis of visibility monitoring including intensive
                            studies such as the Mojave Study to determine the
                            source of aerosol components, its contribution to
                            visibility reduction, and its seasonal variation. This
                            program includes continuing support to and coordina-
                            tion with other agencies concerning visibility character-
                            ization and source  attribution research; the initiation of
                            a visibility trends network to track the effects of
                            controls required by the CAAA of 1990; and the
                            modification of simple photochemical models to
                            include important constituent parameters  that affect
                            visibility reduction.
                                Quality Assurance support will be provided
                            through a standard laboratory and repository of quality
                            assurance materials. Routine and special  audits will be
                            conducted at laboratories  making ambient measure-
                            ments and at compressed  gas vendors. QA guidelines,
                            handbooks, data handling systems and a precision and
                            accuracy reporting system will be maintained and
                            updated. QA procedures,  materials, and audit tech-
                            niques will be developed  for compliance monitoring.

                            Office or                        Total     Percent
                            Laboratory       Contact     Funds($K) In-House

                            AREAL/RTP    William Wilson   2,268       20
                            EMSL/LV      Marc Pitchford     234       29
                            OMMSQA/HQ  Dwight  fflustick
                             National Ambient Air Quality Standards
                             (NAAQS)
Health Effects               Th*8 research program has three major goals: (1)
                             to provide data on health effects of exposures to
                             NAAQS pollutants (primarily O3, NO2, CO2, sulfur
                             oxides, participates and acid aerosols) using both
                             human and animal studies; (2) to develop better
                             models to extrapolate from animals to humans; and (3)
                             to develop improved test methods for research into the
                             physiological responses of humans to the primary air
                             pollutants.
                                Health effects research is conducted to refine and
                             improve the lexicological and epidemiological data
                             base relevant to criteria pollutants. Both human and
                             animal-dose response studies, as well as mathematical
                                    12

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                            modeling, will be given special attention to determine
                            the deposition, clearance, and pulmonary function
                            effects of particulates, alone and in combination with
                            ozone, NO2, and SO2.
                                Research will be done to improve the models used
                            to extrapolate from animal biochemical and metabolic
                            responses to humans. Both human and animal experi-
                            ments will provide data on the functional, morphologi-
                            cal, and biochemical  changes which occur  following
                            exposures to the primary air pollutants, and these data
                            will be used to develop extrapolation models to predict
                            human pulmonary responses, (functional and morpho-
                            logical) to gases and  particulates.
                                Animal, human clinical  and epidemiology studies
                            will provide data to determine the extent to which the
                            primary air pollutants cause  or exacerbate the develop-
                            ment of non-carcinogenic diseases. Effects are studied
                            in both healthy and sensitive (e.g., asthmatic) individu-
                            als. Biological endpoints to be examined include
                            development of cardiovascular or pulmonary disease,
                            aggravation of existing conditions, changes in bio-
                            chemistry and host defense mechanisms, and changes
                            in pulmonary structure or function. Emphasis is
                            currently placed  on determining the acute and chronic
                            effects of O3, NO2, and acid aerosols.
                                The health effects data from this research program
                            are incorporated into EPA criteria documents which
                            are used to set and revise NAAQS.
                             Office or
                             Laboratory

                             HERL/RTP
                             OHR/HQ
                            Total Percent
                 Contact Funds($K) In-House
               Ila Cote
               Susan Perlin
12,601.7
32
 Environmental
 Processes and
 Effects
National Ambient Air Quality Standards
(NAAQS)

    This research provides scientific support of
NAAQS by determining the effects of ozone on
forests, with emphasis on species of economic impor-
tance. Selected forest species will undergo a range of
ozone exposure scenarios possibly experienced in the
forested regions of the United States. The ecophysi-
ological impacts of ozone will be studied in sensitive
tree species, and  studies of the economic impact of
        13

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                           ozone damage will continue on economically and
                           ecologically significant forest species. The research on
                           exposure scenarios and tree responses will be used to
                           assess the risk from ozone on major commercially
                           valuable forest tree species.
                           Office or
                           Laboratory

                           ERL/COR
                           OEPER/HQ
                 Contact

               Bill Hogsett
               Paul Ringold
  Total     Percent
Funds($K) In-House
  2,394.2
      0
40
0
Scientific
Assessment
National Ambient Air Quality Standards
(NAAQS)

    The main objective of the NAAQS scientific
assessment program is to review and revise criteria
documents for sulfur oxides, paniculate matter,
nitrogen oxides, ozone and other photochemical
oxidants, carbon monoxide, and lead. Air Quality
Criteria Documents (AQCDs) are mandated by the
Clean Air Act and, as directed by the Act, are revised
at 5-year intervals. These documents are evaluations of
the available scientific information on the health and
welfare effects of criteria pollutants. As such, criteria
documents are the primary source of information used
by EPA regulatory decision makers in setting or
revising the NAAQS. Criteria document draft materials
are developed by EPA scientists and outside expert
consultants and are peer-reviewed by scientific experts
in public workshops. Subsequently, the document
drafts are revised and through announcements in the
Federal Register, the public is invited to comment on
the resulting external review drafts, which are also
reviewed in public meetings by the Clean Air Scien-
tific Advisory Committee (CASAC) of EPA's  Science
Advisory Board. The final documents are submitted to
the Clean Air Docket and are published concurrently
with the proposed regulatory decisions. In FY92, final
editing and printing will be completed for the revised
Carbon Monoxide AQCD reviewed in draft form by
CASAC in May 1991. Also, public comments  will be
received and analyzed with regard to the First External
Review Draft of a revised Nitrogen Oxides AQCD,
followed by CASAC review of that draft AQCD.
Work will  also be initiated in FY92 on the develop-
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                           ment plan for the Congressionally mandated periodic
                           review of criteria for paniculate matter and sulfur
                           oxides and database assembly/update efforts will
                           continue for acid aerosols, lead, and ozone. Lastly,
                           expert consultation and technology transfer concerning
                           criteria air pollutant issues will continue to be provided
                           in FY92 to support NAAQS development/revision by
                           EPA's Office of Air and Radiation, to assist EPA
                           Regions and States in dealing with local/regional air
                           pollution problems, and to support EPA international
                           activities on subjects related to the criteria air pollut-
                           ants.
                           Office or
                           Laboratory

                           ECAO/RTP
                 Contact

               Lester Grant
  Total     Percent
Funds($K) In-House

  1,874.9     57
Modeling,
Monitoring Systems
and Quality
Assurance
New Source Performance Standards and
State Implementation Plans

    This program provides scientific support on
atmospheric science and monitoring methodologies for
New Source Performance Standards (NSPSs) and State
Implementation Programs (SIPs) to assure attainment
and maintenance of NAAQS. As designated by the
1990 CAAA, a major study of ozone formation in the
Southeast (Southern Oxidant Study) was initiated with
Atlanta, GA, being the focus of much of the program
although other southern areas are involved. This study
will define factors which influence ozone non-attain-
ment including the role of biogenic emissions using
the Regional Oxidant Model (ROM)  to determine the
impact of Volatile Organic Compounds (VOCs) and
NOx emissions  on ozone control strategies. Data from
the *1988 Acid Deposition study is being used to
evaluate the Regional Paniculate Model. Additional
work includes the air dispersion modeling experiments
and testing and model development to modify existing
regulatory models (complex terrain),  to support PM10
regulatory activities and to upgrade regional and urban
paniculate models. This program also provides meteo-
rological guidance and support to ORD laboratories
and other Agency offices as well as research and
development of ambient and source emission methods
for criteria pollutants including their  precursors.

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                           Ongoing work includes PM10 methods evaluations
                           including acid aerosol methods development.
                              To allow States to more easily evaluate SIP
                           revisions, a program will be initiated to incorporate or
                           nest the Urban Airshed Model (UAM) into the Re-
                           gional Oxidant Model (ROM), including the standard-
                           ization of the chemistry and transport modules. The
                           Agency will initiate a program to incorporate major
                           components of the ROM, the Regional Acid Deposi-
                           tion Model (RADM), and the Regional Paniculate
                           Model (RPM) into a new model, MODELS3, which
                           will include upgrades using the latest advances in
                           science and technology in atmospheric physics,
                           chemistry, and computing.
                              The Agency will modify or develop new source
                           monitoring methods for VOCs including continuous
                           monitoring. In addition, the Agency will increase its
                           quality assurance efforts with respect to the National
                           Performance Audit Program (NPAP) which addresses
                           the State and Local Monitoring Network (SLAMS). In
                           addition, the NPAP system will include SIP sites.

                           Office or                       Total     Percent
                           Laboratory       Contact     Funds($K) In-House

                           AREAL/RTP    John Clements   11,973      49
                                          Jack Shreffler
                                          Francis Schiermeier
                           EMSL/LV       James McElroy     872      49
                           OMMSQA/HQ  Dwight fflustick
Environmental
Engineering and
Technology
Demonstration
New Source Performance Standards and
State Implementation Plans

    Research is underway to improve emission
estimation methodologies for criteria pollutants and
their precursors and to evaluate and demonstrate
technologies and prevention approaches which reduce
emissions of VOCs, sulfur oxides (SO^), nitrogen
oxides (NO^), and paniculate matter (PM) from major
point and area sources including utility boilers,
industrial facilities, and consumer products. The
emissions methodologies research is designed to assist
states develop the comprehensive accurate emissions
inventories which, based on the 1990 CAAA, must be
submitted with SIPs and must be updated periodically.
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                            Research to improve VOC emissions estimates for area
                            sources including solvents usage, off-highway vehicles,
                            and gasoline marketing operations is being developed.
                            Increased emphasis is being placed on validating these
                            new area source methodologies. Once validated, the
                            new methods will be used by OAQPS to provide
                            guidance to state and local authorities responsible for
                            preparing ozone and PM10 SIP inventories. The
                            control/prevention research is focused on innovative
                            control approaches for VOC area sources and SO,/NOx
                            controls for industrial facilities. ORD is assisting
                            OAQPS meet the CAAA mandate to establish criteria
                            for regulating VOC emissions from consumer and
                            commercial products. Evaluating and demonstrating
                            approaches to reduce VOCs emitted from non-process
                            related solvent usage is the initial priority. SOX
                            emission reduction research is focused on supporting a
                            pilot scale evaluation of the AD VACATE process at
                            TVA's 10 Mwe Shawnee plant. In-house research to
                            optimize the ADVACATE process, particularly sorbent
                            reactivity, is also being conducted to support the TV A
                            pilot scale demonstration. The NOx control program  is
                            evaluating, developing, and demonstrating advanced
                            combustion modification and flue gas treatment
                            technologies including rebuming, selective catalytic
                            reduction, and non-selective catalytic reduction. There
                            is a renewed interest in advanced Nox controls due to
                            its impact on ozone non-attainment and its contribution
                            to visibility impairment, forest damage and its direct
                            health effects.
                            Office or
                            Laboratory

                            AEERL/RTP
                 Contact

               Jim Abbott
               Everett Plyler
                            OEETD/HQ    Marshall Dick
  Total     Percent
Funds($K) In-House

  2,433.5     59


    280.0     90
Scientific
Assessment
Indoor Air Pollution Activities

    EPA's indoor air research program is geared to
identify, characterize, and rank indoor air problems,
and to assess and implement appropriate  mitigation
strategies. EPA's research and analytical  activities will
pursue both source-specific and generic approaches to
                                   17

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                             indoor air pollution. From a source-specific standpoint,
                             the Agency will identify high-risk pollutant sources
                             and characterize the exposures and health risks of
                             various populations to those sources. At the same time
                             the Agency will also pursue broad, cross-cutting
                             strategies to assess the total exposure of people to
                             indoor air pollutants and to develop mitigation strate-
                             gies that can address multiple pollutants simultaneously
                             through improved building design and management
                             techniques.  Activities in FY92 in the area of scientific
                             assessment include the continued development of risk
                             characterization methodology to assess noncancer
                             health effects; develop and apply methods to assess
                             exposures to both single compounds and mixtures; and
                             continue comprehensive assessment of biocontaminants
                             found in indoor air.

                             Office or                         Total      Percent
                             Laboratory      Contact     Funds($K)  In-House

                             ECAO/RTP      Michael Berry      479.1      39.0
                             Indoor Air Pollution Activities
Health Effects               ^e 8°^ of ^ indoor air health effects research
                             program is to determine whether exposure to indoor air
                             pollution contributes or leads to adverse health effects.
                             Indoor air often contains higher levels of pollutants
                             than outdoor air. Most individuals spend over 80% of
                             their time indoors. Sensitive populations, e.g., children,
                             asthmatics, and the elderly, may be at higher risk from
                             exposure to indoor air pollution. Therefore, the
                             exposure, dose, and effects from indoor air pollution
                             need to be factored into the total risk assessment of air
                             pollution.
                                 A balanced program involving studies with human
                             volunteers and  laboratory animals will be maintained
                             to belter understand "sick building syndrome." The
                             approach to study the effects of indoor air is broad.
                             Work will continue on the evaluation of the dosimetry
                             and effects of environmental tobacco smoke (ETS) in
                             humans. Genetic bioassay studies of organics from
                             indoor air sources will be used to make comparisons
                             of the potential cancer risks form various sources.
                             Human clinical studies of VOCs will continue to be
                             conducted in chambers to determine effects related to

                                     18

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                             the "sick building syndrome." Work will be conducted
                             to characterize people with multiple chemical sensitivi-
                             ties. This work will be critical to understanding the
                             physiological basis for multiple chemical sensitivity.
                             Work will start on exposing rodents to emissions from
                             consumer products, such as carpets.
                             Office or
                             Laboratory

                             HERL/RTP
                             OHR/HQ
                 Contact

                IlaCote
                Susan Perlin
  Total      Percent
Funds($K) In-House
    431.1
13
 Modeling,
 Monitoring Systems
 and Quality
 Assurance
Indoor Air Pollution Activities

    Indoor air research consists of development and
testing of monitoring devices and the design and
implementation of field studies to identify and quanti-
tate pollutants indoors. This research supports investi-
gation of pollutant sources, human exposures and
health effects.
    Methods development research investigates
monitoring devices for pollution monitoring levels in
homes. Results are used to produce information
regarding proper use (sample locations and sample
times) and performance limitations of these devices.
This research will continue to develop and test these
devices, especially personal monitors, in other microen-
vironments (buildings, vehicles, etc.).
    Field studies to investigate spatial and temporal
variations in indoor air quality will be designed and
implemented in  conjunction with an intensive review
of data needs. The program will emphasize research on
"sick building" where elevated levels of pollutants can
be observed  and will characterize the major parameters
that influence indoor air quality. The research is
focusing on  applying the building diagnostic and
measurement methods  development over the past few
years on applications to studies of large buildings. The
results of these studies will be used in developing
guidance on  the most effective design and operation of
large buildings to minimize human exposure to  indoor
air pollutants. Studies developing and refining personal
and area exposure monitors are underway in order to
provide the best possible measurements of specific
pollutants. Finally,  the Agency will initiate a program

        19

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                            to measure biocontamination of buildings through the
                            development of bioaerosol monitoring techniques.
                            Office or
                            Laboratory

                            AREAL/RTP
                            EMSL/CIN
                            OMMSQA/HQ
                                Total     Percent
                 Contact      Funds($K) In-House

               Ross Highsmith   1,389       12
               Alfred Dufour      611       27
               Dwight fflustick
Environmental
Engineering and
Technology
Demonstration
Indoor Air

    Title IV of the Superfund Amendments and
Reauthorization Act (SARA) of 1986 requires the EPA
to establish a research program which includes R&D to
characterize and identify sources of indoor contami-
nants and to control these emissions through technolo-
gies or other mitigation measures. Both of these R&D
areas will be addressed under ORD's indoor air
research program. The source characterization research
program will evaluate emissions from a variety of
indoor sources and will collect data on compounds
emitted, emission rates of these compounds, emission
rate decay,  and the interaction of source emissions with
indoor surfaces (i.e., sinks). Increased emphasis will be
placed on characterizing biocontaminant sources.
Characterization research includes: conducting chamber
studies to determine biocontaminant growth on indoor
surfaces; human exposure studies involving "real"
sources; large chamber test studies to develop methods
and emissions data for activity sources; and multiple
experiments involving sink materials and decaying
sources. Indoor air mitigation research will focus on
evaluating and demonstrating alternative IAQ ap-
proaches including source management, ventilation
strategies, and  air cleaning devices for a variety of
indoor pollutants with increased emphasis on biocon-
taminants. Specific mitigation research includes:
development of methods for evaluating the effective-
ness of air cleaners to control biological pollutants;
initiation of work on evaluating air cleaners for large
commercial spaces; full scale material conditioning and
"bake-out"  studies including evaluation of sink
adsorption/desorption behavior; and evaluations of the
effects of indoor temperature, humidity, and dust level
on biological pollutants.

        20

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                            Laboratory

                            AEERL/RTP
                            OEETD/HQ
                                Total     Percent
                 Contact     Funds($K) In-House
               W. Gene Tucker
               Marshall Dick
3,000.0     25
Environmental
Processes and
Effects
Global Change Research and
Stratospheric Ozone Research

    Concentrations of trace gases that may lead to
climate change are rapidly increasing in the atmo-
sphere, and model projections based on current trends
suggest an increase in global average temperature
during the next 40 to 60 years. Human activities have
increased the levels of emissions dramatically during
the last century and current activities are producing
emissions of carbon dioxide, methane, chlorofluorocar-
bons,  and other gases  in increasing quantities. The
biosphere produces emissions of most of these same
gases  and also serves as a sink for atmospheric carbon.
Unfortunately, the global carbon balance is not
"closed" such that global sources and sinks, and their
rates of change, are known. Rather, atmospheric
concentrations are measured, emissions are estimated,
and the future net rate of increase is inferred from
projections of current  trends.
    The EPA's mission is to protect human health and
the environment The  impacts of global change
represent a significant threat to that mission. The
EPA's objectives  on global change (including both
global climate and stratospheric ozone) are twofold.
First,  the primary EPA objective is to protect and
maintain the Nation's  environmental resources for
present and future generations. Second, to fulfill this
objective, a need  exists to measure, evaluate, and
predict the ecological, environmental, and human-
health consequences of global change.
    Thus,  the EPA's Office of Research and Develop-
ment (ORD) has developed an effective research
strategy to fill major gaps in our national information
needs, to focus on uncertainties identified within the
U.S. Global Change Research Program (USGCRP),
and to complement the many active research efforts on
climate change internationally.
    The EPA/ORD plays critical scientific roles with
the USGCRP  in developing predictive understanding of
       21

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                             global change. Equally important, the EPA/ORD
                             research provides the scientific base for the EPA
                             program offices to develop global change response
                             strategies. Although the EPA/ORD effort is only two
                             percent of the total U.S. program, research funding has
                             been growing at the same rate as overall U.S. global
                             change funding.
                                 The current emphases of the EPA Global Change
                             Research Program (GCRP) are on reducing emissions
                             of carbon, increasing capture and storage of carbon by
                             terrestrial systems, understanding the processes and
                             interactions of climate change, quantifying the effects
                             of climate change in the terrestrial  system, and
                             predicting the impacts of future change. Future
                             initiatives are expected to broaden  our ability to assess
                             (1) emissions of radiatively important trace gases, (2)
                             regional-scale impacts, (3) ecological effects, and (4)
                             carbon sequestration techniques—all of which will
                             increase our ability to develop effective management
                             strategies and policy decisions.
                                 Another important research effort is the investiga-
                             tion of effects of decreasing stratospheric ozone that
                             allows increased ultraviolet flux (UV-B) at the earth's
                             surface. Research conducted under  the Agency's
                             stratospheric ozone depletion program will continue on
                             terrestrial and aquatic ecosystems, human health, and
                             on the atmospheric and biospheric  transport and fate of
                             the proposed chlorofluorocarbon substitutes. Studies of
                             the effects of UV-B radiation on terrestrial ecosystems
                             will emphasize determining the relationship between
                             UV-B dose and other anthropogenic factors, such as
                             global climate change. Research will also stress UV-B
                             effects on the marine food web  and biogeochemical
                             cycling. Support for the Vienna Convention for the
                             Protection of the Ozone Layer and  the renegotiated
                             Montreal Protocol will continue, in cooperation with
                             other nations.
                                 Although the EPA research effort represents only
                             two percent of the Federal program budget, the
                             Agency's effort is an integral part of U.S. research on
                             global change. The Office of Research and Develop-
                             ment is responding to the need for  critical input in
                             making sound regulatory and policy decisions, and
                             specifically, credible scientific data so that we can
                             predict future change better, define effects more
                             accurately, and evaluate societal response options more
                             accurately. The EPA is committed to ensuring that

                                    22

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                             U.S. policy fosters environmental protection, as well as
                             sustainable utilization of its natural resources. It is
                             recognized that human-induced climate change is
                             likely; however, the current predictions are uncertain,
                             the potential effects are poorly defined, and the
                             solutions are not readily available or apparent
                                 The EPA  GCRP began several years ago with the
                             recognition that  there are intimate links between
                             human-induced changes in emissions of radiatively
                             important trace gases, changes in atmospheric chemis-
                             try, changes in climate, and impacts of the resultant
                             climatic and chemical environment on human society.
                             Thus, the GCRP initiated research to link these four
                             areas, not only to ensure strong links between the
                             specialized research areas, but also so that current
                             research within these areas would be of the type
                             needed both by other scientists and by policy makers.
                                 The interaction of policy concerns and scientific
                             research embodied in the EPA GCRP requires that the
                             research products provide a scientific foundation for
                             policy development and analysis. Accomplishing this
                             depends not only on  the quality of the research
                             performed in the GCRP, but on the ability of the
                             researchers to  interpret their own results and the results
                             of other programs in light of environmental policy.
                                 The EPA  GCRP focuses on those scientific issues
                             that are the most relevant to policy formation, while
                             striving to maintain the proper balance of responsive-
                             ness to changes  in policy directions and the scientific
                             flexibility to respond to new scientific questions as
                             they arise.
                                    23

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                          Office or
                          Laboratory

                          OEPER/HQS
                          AREAL

                          AEERL
                          ERL/ATH

                          ERL/COR
                          ERL/DUL
                          ERL/NARR
                Contact

              Robert C.
                Worrest
              Paul Ringold
              Lowell Smith
              Dennis Trout
              Sharon LeDuc
              Joe Sickles
              Jim Abbott
              Lee Mulkey
              Lee Wolfe
              Peter Beedlow
              John Eaton
              Hal Walker
              Henry Lee II
  Total     Percent
Funds($K) In-House
 26,000
25
Environmental
Engineering and
Technology
Demonstration
Global Climate Change

    As a result of increased national and international
concern regarding potential significant changes in
global climate, OEETD has expanded its program in
this area. The expanded global emissions research
includes development of global and regional emission
factors, activities, and functions for anthropogenic and
biogenic sources of radiatively important trace gases.
The OEETD will support ORD's research on evaluat-
ing the enhancement of the terrestrial biosphere as a
CO? sink; emphasis will be on assessing biomass
utilization options.
                          Office or
                          Laboratory

                          AEERL/RTP
                          OEETD/HQ
                Contact

              Dick Stern
              Marshall Dick
  Total    Percent
Funds($K) In-House
  4,720
      0
10
 0
Modeling,
Monitoring Systems
and Quality
Assurance
Clean Air Act Amendments

    With respect to the Attainment of Air Quality
Standards, research includes ozone epidemiology
studies, studies on regional visibility and haze, ozone
ecosystem effects studies, and additional health criteria
assessments. Additional support for SIPS and new

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                            source standards include the development of improved
                            emission inventory methods, improvements in the
                            ROM as well as additional applications initiation of
                            the development of a more advanced model incorporat-
                            ing previous models (MODELS3), additional ambient
                            and source monitoring methods development for O3
                            and its precursors and other pollutants, and engineering
                            efforts to develop and evaluate techniques for the
                            control of VOCs and NO^. Air toxics studies include
                            additional risk studies for air toxics in support of
                            CAAA as well as studies and measurement methods
                            for area-wide and point source determinations, and
                            Great Waters toxic deposition studies. Mobile source
                            studies are concentrating on risks from alternate fuels
                            including atmospheric transformation studies as well  as
                            human exposure studies to formaldehyde and other
                            compounds. The acid deposition program includes
                            demonstrations of NOx control approaches, updating
                            emission inventory methodologies, aquatic effects
                            monitoring in sensitive regions, forest effects monitor-
                            ing in select high elevation areas, and visibility
                            monitoring in nonclass I areas including eastern United
                            States.

                            Office or                        Total     Percent
                            Laboratory       Contact     Funds($K) In-House

                            OMMSQA/HQ  D. fflustick      19,652.1     10
                            AREAL/RTP    J. Clements
                            EMSIVLV      J. McElroy
                            OEPER/COR    T. Murphy
                            HERL/RTP     Ila Cote
                            ECAO/RTP     Les Grant
                            ECAO/CINN    C. Sonich-Mullin
                            OHEA/HAG    C. Ris
                            OHEA/EAG     M. Callahan
                            AEERL/RTP    F. Princiotta
                            Health Effects Institute

Health Effects               A significant part of the health effects research on
                            mobile source emissions is conducted through the
                            Congressionally mandated Health Effects Institute
                            (HEI). HEI is jointly sponsored by EPA, through
                            extramural funding,  and the automobile industry to

                                   25

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                            perform research on the health effects of pollutants
                            related to mobile sources.
                                The research focuses on various mobile source-
                            related pollutants, including carbon monoxide, oxidants
                            (ozone and nitrogen dioxide), diesel exhaust and
                            alternative fuels such as methanol. Important areas of
                            health research conducted by HEI include: develop-
                            ment and use of biological markers; identification and
                            characterization of susceptible populations; determina-
                            tion of dose to target tissue; assessment of susceptibil-
                            ity to  infection; examination of mechanisms of injury
                            and/or disease; and evaluation of neurotoxicological
                            and behavioral effects. HEI is expanding its research
                            on the health effects of alternative fuels by sponsoring
                            several methanol inhalation studies in rats and mon-
                            keys that focus on metabolism,  pharmacokinetics, and
                            behavioral developmental effects of offspring exposed
                            in utero.
                            Office or
                            Laboratory

                            HERL/RTP
                            OHR/HQ
                                Total     Percent
                 Contact      Funds($K) In-House
                Ila Cote         3,000.0
Modeling,
Monitoring Systems
and Quality
Assurance
Deposition Monitoring and Understanding
Atmospheric Processes

    The current research program includes: (1) The
continued development of improved methods for
estimating area and point source emissions. This
includes the development of improved data collection
procedures at the sources, States and EPA as well as
improved data quality assurance procedures; (2) The
maintenance of emission projection models specific to
major source categories.  These models are used to
analyze emission management strategies; (3) Comple-
tion of the joint U.S./Canadian evaluation of the
RADM along with the Canadian ADOM model; (4)
Use of RADM to: optimize CAAA program implemen-
tation through forecasting the effects of emissions
trading, coal moratoriums, and related interstate issues;
extrapolating site-specific deposition monitoring data
for baseline trends determinations; supporting
interprogram effects of instituting controls on VOCs
and oxidants along with  acid deposition; (5) Merging
       26

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                            of RADM and ROM modeling capabilities, enhance-
                            ment of nitrogen chemistry components, building a
                            comprehensive modeling system to study urban and
                            regional oxidant, nitrogen, and air toxic issues; and (6)
                            Downscaling the RADM model to desk top versions
                            for use by Regional and State offices as well as other
                            sources.
                                The existing monitoring system for wet and dry
                            deposition will be expanded and upgraded as specified
                            by the 1990 CAAA to meet spatial and temporal trend
                            detection  needs. New monitoring will also be initiated
                            to determine visibility trends in the eastern half of the
                            U.S. Finally, a long term  program to study the effects
                            of wet and dry deposition on stone and metals will be
                            initiated.

                            Office or                        Total     Percent
                            Laboratory       Contact     Funds($K) In-House

                            AREAL/RTP   Jim Vickery      6,160       9
                            OMMSQA/HQ  Dwight  Hlustick
Environmental
Engineering and
Technology
Demonstration
Energy

    The goal of the Multimedia Energy research and
development program is to provide EPA Program and
Regional Offices, Federal, State, and local govern-
ments, and industry with the scientific information to
guide the development and utilization of energy
resources in an environmentally acceptable manner.
The major objective is to support implementation of
the acid rain provisions contained in Title IV of the
1990 CAAA including demonstrating innovative
technologies (Limestone Injection Multistage Burner,
LIMB) to reduce acid rain precursors (NOx and SOx).
    Equipment installation for the Yorktown LIMB
demonstration will be completed with the unit avail-
able to begin testing in January 1992. During the rest
of the fiscal year, optimization and performance testing
of the system will  be conducted. In addition, labora-
tory development work on improved sorbents, reactiva-
tion of sorbents and other general support to the  LIMB
processes will be conducted.
                                   27

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Air
                         Office or                     Total    Percent
                         Laboratory      Contact     Funds($K) In-House

                         AEERL/RTP   Mike Maxwell   3,318.6     30
                         OEETD/HQ    Marshall Dick     200      77
                               28

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 Drinking Water
Health Effects
Scientific
Assessment
 Health Effects of Drinking Water
 Contaminants

    This research program provides dose-response data
 on organic and inorganic contaminants found in
 drinking water. In addition, lexicological methods are
 developed and validated for the purpose of improving
 the relevance of toxicological data to regulatory issues
 and to improve the risk characterization process.
    Research will focus on determining the health
 effects resulting from exposure to chlorine and ozone
 disinfectants and their by-products. Work will be done
 to improve methods for extrapolating health effects
 research data in order to assess the risks associated
 with simultaneous exposure to multiple chemicals in
 binary and complex mixtures. Epidemiology  studies on
 the relationship between disinfectants and cancer, and
 disinfectant use and waterborne infectious disease will
 be conducted.

 Office or                        Total     Percent
 Laboratory       Contact     Funds ($K) In-House

 HERL/RTP      JackFowle       4,776.7     33
 OHR/HQ        Rebecca Calderon

 Health Effects of Drinking  Water
 Contaminants

    Development of national drinking water and health
 advisory guidance given to the States requires an
 assessment of the potential hazard to human health
 from exposure to chemicals in drinking water. The
 health assessments prepared under this program take
 the form of both  criteria documents and health adviso-
ries. These documents are comprehensive reviews of
the health effects associated with exposure to contami-
nants in  drinking water. They specifically evaluate the
relevant  scientific data describing the physical and
chemical properties, the pharmacokinetics, the toxicity
and carcinogenicity in animals and humans, and the
mechanisms of toxicity. The health assessments are
prepared for various chemicals as requested by EPA's
Office of Science and Technology (OST). This risk
assessment process enables OST to establish  a Maxi-
mum Contaminant Level Goal (MCLG), representing a
                                   29

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Drinking Water
                          level designed to preclude the risk of an adverse effect
                          on human health.
                          Office or
                          Laboratory

                          ECAO/CIN
                Contact

               Linda R. Papa
   Total     Percent
Funds ($K) In-House
    902.8
71.2
Modeling,
Monitoring Systems
and Quality
Assurance
Ground Water Research

    Geophysical research will be conducted for
mapping and monitoring fluid movement from injec-
tion wells; for detecting near-surface contamination
from abandoned wells and movement along fracture
zones; and, for the evaluation of seismic hazards
associated with the underground injection process. In
support of EPA's Wellhead Protection Program,
guidance on monitoring system design will be devel-
oped. Additional research will involve the quantifica-
tion of the spatial characteristics of pollutants in
drinking water and the application of modeling
techniques to assist in groundwater quality sampling
decisions, including methods for using the Geographic
Information  System (GIS) for enhancing data manage-
ment and analyses.

Office or                       Total     Percent
Laboratory      Contact     Funds ($K) In-House
                           EMSL/LV      Robert Snelling
                           OMMSQA/HQ  Bill Stelz
                                508.6
              37
Environmental
Processes and
Effects
Ground Water

    Ground water is a major source of drinking water
for the nation. This research program provides both
technical information and improved methods for
predicting contamination movement and transforma-
tion. The research focuses on methods development for
studies of subsurface transport and fate processes  such
as biological transformation, oxidation-reduction,
hydrolysis, and ion exchange. Facilitated transport
research will address complex mixtures processes such
                                  30

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Drinking  Water
                           as multiphase transport and solvent composition effects
                           on sorption.
                              Field evaluation of techniques for determining the
                           mechanical integrity and adequacy of construction of
                           injection wells will occur.
                              Methods will be developed for delineating well-
                           head protection areas, incorporating multiple sources of
                           pollution into wellhead protection models, and for
                           performing risk assessments in wellhead protection
                           areas.
                              A new program entitled Midwest Agrichemical
                           Surface/Subsurface Transport and Effects Research
                           (MASTER) will be implemented. This is a cooperative
                           effort with  USD A and USGS. The research will
                           evaluate how agricultural management practices affect
                           our ecological  resources with a goal towards optimiz-
                           ing the ecological health of agricultural watersheds.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds  ($K) In-House

                           RSKERL/ADA  James McNabb    3,326.9     38
                           OEPER/HQ     Barbara Levinson 1,348.7     25
                           ERL/ATH       LeeMulkey        654.3     12
                           ERL/COR       Robert Lackey     343.5      5
                           ERL/DUL       Nelson Thomas    343.8      6
                           EMSL/LV       JoeD'Lugosz      575.0      0
Environmental
Engineering and
Technology
Demonstration
Drinking Water Technology

    This program supports the revisions in the Na-
tional Drinking Water Standards. Technology perfor-
mance and cost data, to support maximum contaminant
standards under the Safe Drinking Water Act and its
Amendments, is obtained through ongoing treatment
research and evaluations.
    Focus is on treatment to control physical and
chemical contaminants and microbiological contamina-
tion. Research in treatment technology addresses
removal of: disinfection by-products and their precur-
sors, inorganic contaminants, maintaining water quality
in the distribution system, and developing supporting
cost data.
    Major treatment occurrence issues include:
                                  31

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Drinking Water
                                   Assessing formation mechanisms and condi-
                                   tions for disinfection by-products.
                                   Evaluating control techniques for the by-
                                   products.
                                   Developing and evaluating technology for
                                   small systems, including point-of-use/point-of-
                                   entry treatment device evaluation.
                                   Evaluating alternative disinfection processes.
                                   Evaluating technology on corrosion of lead
                                   and copper.
                                   Investigations into means of reducing lead in
                                   hard and soft drinking water.
                                   Evaluation of point-of-entry systems for radon
                                   removal and inactivation of cryptosporidium
                                   oocysts.
                                   Developing cost information for treatment
                                   processes and entire systems. Evaluations will
                                   also be made of the tradeoffs in planning for
                                   rehabilitation of older water systems.
                           Office or
                           Laboratory

                           RREL/CIN
                           OEETD/HQ
                 Contact

               Robert Clark
               Don Tang
   Total      Percent
Funds ($K) In-House
   2,017.7
63
Modeling,
Monitoring Systems
and Quality
Assurance
Drinking Water Technology

    This program conducts research to develop and
standardize the technically and economically feasible
analytical methods needed to monitor chemical and
microbiological contaminants in drinking water. To
ensure that data of known quality are obtained,
chemical and biological quality control and reference
materials are made available, and semiannual labora-
tory performance evaluations of Agency, state, munici-
pal, and utility laboratories are conducted.  Analytical
methods are evaluated through single- and
multilaboratory methods validation studies. In  support
of the monitoring laboratory certification program,
formal training courses are conducted, and each of the
ten regional laboratories is evaluated through an on-site
visit at least once every three years.
                                   32

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Drinking Water
                     Office or                  Total    Percent
                     Laboratory     Contact    Funds($K) In-House

                     EMS1VCIN    Thomas Clark   2,788.6    62
                     EMSL/LV     Robert Snelling    259.9    51
                     OMMSQA/HQ BUI Stelz
                           33

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Water  Quality
Modeling,
Monitoring Systems
and Quality
Assurance
Water Quality Based Approach/Permitting

    The monitoring research program develops and
standardizes methods to identify and measure chemical
and biological pollutants and to determine the biologi-
cal integrity of ecosystems. To ensure that data of
known and acceptable quality are acquired, quality
assurance support is provided in the form of quality
control and reference materials, biological sampling
guidelines, method performance criteria, and semian-
nual laboratory performance audits. Research seeks to
improve the sensitivity of chemical methods for
measuring toxic chemicals in water and sediment.
Biological methods are developed to screen ambient
waters and sediments for chronic and acute toxicologi-
cal effects of pollutants. Research is conducted to
develop procedures that use bioindicators of exposure
to environmental contaminants rather than identifying
and measuring specific substances as contaminants.

Office or                       Total     Percent
Laboratory       Contact     Funds ($K) In-House

EMSL/CIN      Gerald McKee    2,352.0     78
OMMSQA/HQ  Bill Stelz
Scientific
Assessment
Water Quality Based Approach/Permitting

        EPA's overall research program with regard to
water emphasizes development of the scientific and
technical base to help States develop site-specific
standards and to conduct use-attainability analyses. The
scientific assessment program will provide guidance
for determining risk of adverse human health effects
from exposure to mixtures of toxic chemicals, and will
evaluate site-specific health hazards as required by the
States and EPA. As a part of this effort, EPA develops
the specific risk assessments which are used as
benchmark guidance to the States.
                           Office or
                           Laboratory

                           ECAO/CIN
                 Contact

               Linda R. Papa
   Total     Percent
Funds ($K) In-House
    283.6
79.8
                                   34

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Water  Quality
Environmental
Processes and
Effects
Water Quality Based Approach/Permitting

    A water quality-based approach to pollution
control provides for correction of ambient water
quality problems that remain after mandated pollution
control technology (e.g., secondary treatment, effluent
guidelines) is in place. This requires the ability to
translate water quality standards into specific effluent
conditions and discharge limitations for municipalities
and industries. Research will be undertaken to provide
the necessary information and scientific tools, includ-
ing: water quality criteria development/modification;
sediment quality assessment techniques; wasteload
allocation techniques; and complex effluent testing
procedures. Research on the water quality functions of
wetlands, and cumulative effects of wetlands loss and
the impacts of mitigation of wetlands will also be
conducted to support the Agency's "No-Net-Loss" of
wetlands policy.

Office or                       Total      Percent
Laboratory       Contact     Funds  ($K) In-House

ERL/ATH      Robert Swank    1,076.1     67
ERL/COR      Tom Murphy     2,308.2     20
ERL/DUL      Nelson Thomas   4,219.8     57
ERL/NARR     Norbert Jaworski  2,153.8     57
ERL/GB        Raymond Wilhour   170.1      0
OEPER/HQ     ChiehWu          977.4     78
Modeling,
Monitoring Systems
and Quality
Assurance
Industrial Wastewater Treatment
Technology

    Research supports the Agency in implementation
of technology-based effluent limitation regulations and
modification of enforcement activities as required by
water quality-based permit adjustments. Methods are
developed and standardized to provided technically and
economically feasible methods to determine regulated
organic and inorganic contaminants and to ensure that
biological limits are not exceeded. In support of the
National Pollution  Discharge Elimination System
(NPDES) program, performance characteristics (accu-
racy, precision, and detection limits) of available
methods for high priority industrial wastewater
pollutants are determined through single and
       35

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Water  Quality
                           multilaboratory evaluations: when necessary, method
                           deficiencies are corrected or new methods development
                           research is initiated. The research program supports
                           NPDES quality assurance by designing and providing a
                           source of calibration, quality control, and reference
                           materials required for both chemical and biological
                           methods. Through the annual Discharge Monitoring
                           Report  Quality Assurance (DMRQA) study, perfor-
                           mance evaluation studies are conducted to ensure that
                           acceptable data are acquired by some 7,000 major
                           NPDES permittees.

                           Office or                       Total     Percent
                           Laboratory      Contact      Funds($K) In-House
                           EMSL/CIN     Gerald McKee
                           OMMSQA/HQ  Bill Stelz
                                 793.1
73
Environmental
Engineering and
Technology
Demonstration
Wastewater Treatment Technology

    The wastewater technology research program
provides the technical information and engineering
assistance needed to develop and implement the
regulations and guidance for disposal of sludge and
control of pollution from municipal treatment plants to
bring plants into compliance with state discharge
permits. This program also provides the research in
industrial wastewater characterization and control
technology needed to support the National Pollutant
Discharge Elimination System. The program focuses
on stormwater and combined sewer overflow, espe-
cially on toxic aspect, and best conventional technol-
ogy and best available technology limitations in
industrial wastewaters. Design, cost and performance
information for sludge stabilization, pathogen reduc-
tion, and dewatering processes will be proved to
support sludge regulation implementation and refine-
ment Emphasis  is also on supporting the new
wastewater treatment technologies development and
infrastructure protection, particularly with regard to
small communities.
                                  36

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Water Quality
                          Office or
                          Laboratory

                          RREL/CIN
                          OEETD/HQ
                Contact

               Subhas Sikdar
               Don Tang
   Total     Percent
Funds ($K) In-House
   1,398.7
  40
Scientific
Assessment
 Wastewater Treatment Technology

    The scientific assessment program provides human
risk assessment methodologies for chemicals and
pathogens in support of regulatory decision making on
the use and disposal of municipal sludge. Numerical
criteria and/or management practices for pollutants in
sludge are developed based on the human risk assess-
ment methodologies. The use and disposal options are
landfilling, land application (including distribution and
marketing), incineration, disposal, and surface im-
poundment.
                          Office or
                          Laboratory

                          ECAO/CIN
                Contact

              Linda R. Papa
   Total     Percent
Funds ($K) In-House
    405.6
34.7
Environmental
Processes and
Effects
 Wastewater Treatment Technology

    This research will identify and determine distribu-
tion of unlisted chemicals in industrial wastewaters.
Compounds that can be identified by empirical mass
spectra matching as well as those that elude identifica-
tion by this technique will be included. This research
will also study the biological functions of constructed
wetlands in the treatment of wastewater from small
communities and acid mine drainage.

Office or                      Total     Percent
Laboratory      Contact     Funds ($K) In-House

ERL/ATH      William Donaldson  153.3    100
ERL/COR      Richard Olson      85.4     0
ERL/DUL      William Sanville    90.4     0
OEPER/HQ    Chieh Wu
                                 37

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Water Quality
Environmental
Processes and
Effects
Marine, Estuaries, and Lakes

    This program has three components: ocean
disposal, coastal waters, and Great Lakes.
    To support ocean disposal permit decisions, there
is a need to provide decision makers with rationale and
procedures which are scientifically sound. These
should provide guidance for the acquisition of informa-
tion and the interpretation of this information to
support ocean disposal permit decisions. Under the
ocean disposal research program, emphasis will be
given to the development and testing of procedures to
better evaluate the impacts of ocean disposal actions;
development of procedures to satisfy monitoring needs
for permit, surveillance, and hazard assessment
application; and development of procedures for
predicting the bioaccumulation of contaminants and
evaluation of the significance of bioaccumulation
processes, resultant tissue residues and biological
effects.
    Methods for better source control decisions in the
NPDES  and construction grants program are needed
for estuaries and near coastal waters. Emphasis will be
given to the development/testing of biomarker assess-
ment methods, development of wasteload allocation
models for estuaries, and studies of ecosystem recov-
ery.
    The Great Lakes research program will measure,
describe and predict the distribution, movement, fate,
and effects of toxic substances in nearshore "areas of
concern" identified by the US/Canada Water Quality
Agreement Research will also be conducted on the
impact of introduced, non-indigenous species on in-situ
ecosystems water quality. Emphasis will be given to
problems involving in-place pollutants and mass
balance  modeling. This program will also provide the
International Joint Commission (IJC), the Great Lakes
National Program Office (GLNPO), EPA Regions and
Great Lakes states with technical support and research
data synthesis related to activities under the US/Canada
Water Quality Agreement.
                                   38

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Water  Quality
                           Office or                      Total     Percent
                           Laboratory      Contact     Funds ($K) In-House

                           ERL/NARR    Norbert Jaworski 3,271.8    83
                           ERL/GB       Rod Parish        101.4    100
                           ERL/DUL      Oilman Veith    4,380.1    10
                           OEPER/HQ    Steve Cordle        40.8     0
Modeling,
Monitoring Systems
and Quality
Assurance
Marine, Estuaries, and Lakes

    The aim of this program is to develop, evaluate,
and validate standardized chemical, biological and
microbiological methods for the determination of
contaminants and biological integrity in marine,
estuarine and other salt water matrices. The near-
coastal areas of the U.S. are economically some  of our
richest and most sensitive ecosystems.
    Currently, EPA does not have standardized
methods and reference materials for monitoring,
assessment and regulation of chemical constituents and
pollutants in marine and estuarine waters and sedi-
ments.
    Available  methods will be reviewed for applicabil-
ity in  marine and estuarine  environments and revised
as necessary. Methods not applicable will be modified
or new methods development initiated, as needed,
using  state-of-the-art technology. Ongoing methods
development activities and plans for new methods
research will be reviewed and modified, if appropriate,
to include marine and estuarine methods. Research will
be conducted to determine the applicability of existing
materials for use as quality  control and performance
evaluation samples.
                           Office or
                           Laboratory
                Contact
  Total     Percent
Funds($K) In-House
                           EMSL/CIN     Thomas Clark
                           OMMSQA/HQ  Bill Stelz
                                573.8
             68
                                  39

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Hazardous Waste
Environmental
Engineering and
Technology
Demonstration
Alternate Technologies

    The treatment program examines both existing and
emerging alternative techniques for treating or detoxi-
fying hazardous materials.  Emphasis continues to be
placed on those waste streams which will be banned
from land disposal facilities.
    Research and demonstration of existing and
emerging technologies will be conducted for those
waste streams assigned high priority by the Office of
Solid Waste and Emergency Response (OSWER),
waste streams which are difficult to cost-effectively
treat by available technology, and waste streams with
high potential for hazardous air emissions. Emphasis
will be on characterization and pilot-scale testing of
newly listed hazardous waste streams. Assistance in
the review of permits for alternative technologies  and
project monitoring for evaluation of such technologies
will be provided. Other types of information transfer
activities such as workshops, seminars, and guidance
documents will be prepared in conjunction with the
Center for Environmental Research Information.
                           Office or
                           Laboratory

                           RREL/CIN
                           OEETD/HQ
                Contact

               R. Hill
               S. Sikdar
               H. Freeman
               B. Krishnan
   Total     Percent
Funds ($K) In-House
   2,644
    215
20
50
Environmental
Processes and
Effects
Alternate Technologies

    New emphasis is being placed on research for
developing bioremediation technologies specifically
applicable to Resource Conservation and Recovery Act
(RCRA) hazardous wastes. This major program will
complement ongoing studies being conducted for
Superfund sites but will emphasize biological treatment
of known industrial chemicals rather than of complex
mixtures. Studies here will be directed at improving
the base of scientific knowledge as it applies to
optimizing  the application of in-situ bioremediation.
Improvements in the contact between the microorgan-
isms and the chemicals to be degraded, and in the
delivery to the subsurface of nutrients and environmen-
                                  40

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Hazardous Waste
                           tal amendments, such as oxygen, will assure maximum
                           viability and efficacy. All extramural monies will be
                           expended by the participating laboratories subject to
                           final planning actions.

                           Office or                        Total     Percent
                           Laboratory       Contact     Funds($K)  In-House

                           RSKERL/ADA  John T. Wilson      12.2    100.0
                           ERL/ATH      Rosemarie Russo    14.1    100.0
                           ERL/GB       HapPritchard       20.8    100.0
                           OEPER/HQ     Will C. LaVeille  1,211.6     0.0
Environmental
Engineering and
Technology
Demonstration
Incineration

    The incineration research program focjises on the
problem areas of organic destruction and metals
partitioning and industries characterizing performance
of existing thermal technologies; developing methods
of rapid cost-effective compliance monitoring of these
facilities; characterizing the products of incomplete
combustion and their formation and destruction and
control conditions; and developing methods to predict
performance to avoid process failure and control
process reliability. In addition, technical assistance on
specific regulatory or remediation requirements is
provided. The research is conducted at laboratory-,
pilot-, and  full-scale operations which simulate actual
incineration/boilers/kilns. Pilot-scale facilities are
located at Research Triangle Park and Jefferson,
Arkansas. The hypotheses from this program are
verified in  full-scale field tests. The program examines
conventional incineration as well as high temperature
industrial processes.
    Research on the incineration of municipal waste
will also be conducted to determine the effectiveness
of the process in destroying the hazardous components
of the waste and to determine  the characteristics of the
ash produced.
                           Office or
                           Laboratory

                           RREL/CIN
                           AEERL/RTP
                           OEETD/HQ
                 Contact

               C. Dempsey
               R. Hall
               B. Krishnan
   Total     Percent
Funds ($K) In-House
    873
    300
     50
 33
100
100
                                  41

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Hazardous Waste
Health Effects
Incineration

    Research on this issue focuses on improving the
assessment of risks from emissions and residuals of
hazardous waste management practices, especially
incineration. Current efforts are focused on research to
explore the relationship between exposure to disposed
incineration residuals containing metals and dose to
target tissues. This pharmacokinetics research improves
our understanding of the principles governing dosim-
etry of metals for risk assessment
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                Contact

               Robert Dyer
               Thomas Miller
   Total     Percent
Funds ($K) In-House
    748.7
 42
Environmental
Engineering and
Technology
Demonstration
Land Disposal

    With regard to land disposal, synthetic and clay
liners will be studied and the effectiveness of alterna-
tive closure and monitoring procedures for surface
impoundments will be investigated. Technical Resource
Documents will be updated for use by regional and
state agencies for permitting hazardous waste disposal
facilities and  for enforcing applicable regulations. This
program will  update documents for disposal facility
design, operation, maintenance, and closure.
    Research is also being conducted to characterize
air emissions from  hazardous waste treatment, storage,
and disposal facilities and to assess methods to control
them.
                           Office or
                           Laboratory

                           RREL/CIN
                           OEETD/HQ
                Contact

               R. Landreth
               B. Krishnan
   Total     Percent
Funds ($K) In-House
    797
     50
 31
100
                                 42

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Hazardous Waste
Environmental
Engineering and
Technology
Demonstration
Pollution Prevention

    The Pollution Prevention Research Program
(PPRP) supports the development and demonstration of
low and non-waste production technologies, and
encourages the development of products that do not
present environmental problems relevant to their
manufacture, use, and disposal. The overall goal of the
program is to support the adoption of techniques and
technologies  that result in the elimination of pollution
at the source of its production, as opposed to control-
ling pollution through increasingly stringent treatment
options.
    Major elements of the program include a program
to demonstrate innovative waste reduction technologies
carried out in cooperation with state and local waste
reduction programs, a program to encourage the
adoption of pollution prevention  techniques in other
federal agencies, and a program to encourage the use
of waste minimization assessments to identify waste
reduction opportunities at industrial sites. This last
program has  produced a generic  assessment manual
and pollution prevention guides in seven industries.
    Future activities under the PPRP will highlight
socioeconomic studies, anticipatory research to identify
future opportunities for pollution prevention strategies,
and technology transfer.
                            Office or
                            Laboratory

                            RREL/CIN
                            OEETD/HQ
                 Contact

               H. Freeman
               B. Krishnan
   Total     Percent
Funds ($K) ID-House
   2,400
    300
0
0
Health Effects
Municipal Solid Waste

    Research on the potential carcinogenic and non-
carcinogenic health effects of emissions and residues
from municipal waste combustion (MWQ will focus
on the following objectives: Perform a comparative
assessment of the  mutagenicity and carcinogenicity of
the emission products from MWC in comparison to
other industrial and residential combustion sources.
Identify the principal mutagenic/carcinogenic chemicals
in MWC emissions by using bioassay-directed chemi-
cal characterization. Support the evaluation of engi-

       43

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Hazardous  Waste
                          neering and control technology parameters to deter-
                          mine operational conditions which will minimize risk.
                          Evaluate the toxicity of MWC emissions, collected
                          after dilution, in in vivo target cell bioassays and short-
                          term in vivo assays.
                          Office or
                          Laboratory

                          HERL/RTP
                          OHR/HQ
                Contact

              Robert Dyer
              Thomas Miller
   Total     Percent
Funds ($K) In-House
    643.9
49
Scientific
Assessment
Municipal Solid Waste

    A user-friendly computer programmed program-
mer's guide will be developed for the methodology for
assessing health risks associated with indirect exposure
to combustor emissions. The method will also be used
in several test cases. Available information on potential
hazards from various waste management options will
be surveyed and compiled for use in developing a
methodology for comparative risk assessment
                          Office or
                          Laboratory

                          ECAO/CIN
                              Total     Percent
                Contact     Funds ($K) In-House
               Lynn Papa        658
               Cindy Sonich-Mullin
              30.1
Environmental
Engineering and
Technology
Demonstration
Municipal Solid Waste

    ORD is expanding research in municipal solid
waste (MSW) management Research will focus on
techniques for improving strategic planning, source
reduction recycling and improving long-term perfor-
mance of land disposal units. MWC research will
continue to provide the scientific  bases for air emission
regulations; evaluation of mercury emissions, CDD/
CDF formation  and gas and heterogenous phase
organic pollutant reaction; and assess potential effects
of materials recovery on MWC processes. MWC
residue research will emphasize the environmental
effects of using the residues as useful products, sources
of toxic constituents in MSW that affect residue
characteristics, and speciation of Ihe toxic constituents

       44

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Hazardous  Waste
                           in the ashes. MITE, ORD's program to demonstrate
                           and evaluate innovative technologies for improving
                           municipal solid waste, will focus on demonstrating
                           processes for converting secondary materials into
                           useful commercial products.
                           Office or
                           Laboratory

                           RREL/CIN
                           AEERIVRTP
                           OEETD/HQ
                 Contact

               R. Landreth
               R. Hall
               B. Krishnan
   Total     Percent
Funds ($K) In-House
   2,600
    980
    735
 35
 35
100
Modeling,
Monitoring Systems
and Quality
Assurance
Municipal Solid Waste Monitoring

    Support is provided to the Office of Solid Waste
(OSW) to improve the siting and monitoring of
municipal waste combustion disposal facilities and to
identify key groundwater monitoring issues pertaining
to municipal waste combustion ash disposal facilities.
    The 1984 amendments to RCRA require the EPA
to revise where necessary the criteria for Subtitle D
facilities, however, technical  information in the
monitoring area is needed to support regulatory
development Further, in many coastal areas, municipal
disposal facilities are located in or near wet environ-
ments, posing special environmental problems. Ques-
tions concerning the environmental adequacy of
municipal waste combustion  disposal are delaying the
construction of needed combustion disposal  capacity.
    Existing data on leachate characteristics and
ground-water contamination around types of Subtitle D
facilities and municipal waste combustion ash  monofils
are being collected on a continuous basis and evalu-
ated. Ground-water monitoring parameters for  ash
landfills will be developed. Potential indicators of
biological contamination will be identified.
    Wet environments will receive special emphasis
with an evaluation of siting practices relative to wet
environments being conducted. Methods for monitoring
in or near wet environments  are being evaluated.
    Existing published and unpublished environmental
monitoring data for environmental impacts of monofil
and co-disposal ash disposal  facilities are being
identified and evaluated. Existing municipal waste
combustion disposal facilities sites are being character-

       45

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Hazardous  Waste
                            ized and evaluated. Monitoring and site characteriza-
                            tion guidance and an expert system for permit writers
                            will be developed.
                            Office or
                            laboratory
                 Contact
  Total     Percent
Funds($K) In-House
                           EMSL/LV      Eugene Meier
                           OMMSQA/HQ  Ken Sala
                                 483.9
              11
Environmental
Processes and
Effects
Waste Characterization

    Regulation of hazardous wastes in the most cost-
effective manner requires methods and data for
predicting toxicity of waste materials and evaluating
the concentrations of these materials at some point of
exposure, and then integrating these methods for
different media into single evaluation techniques which
incorporate uncertainty into the predictions.
    ERL/Duluth is developing procedures and data to
evaluate waste characteristics and closure criteria for
impacts on aquatic habitats and life forms. Methods
are being developed for assessing effects of waste
mixtures and constituents on aquatic organisms and on
habitats. Protocols for applying these approaches to
field sites are being generated.
    Providing field-evaluated methods and data to
predict and remediate the concentrations of hazardous
chemicals in the subsurface environment from the
treatment, storage, or disposal of wastes is the thrust of
the program at RSKERL/Ada. Physical, chemical, and
biological processes that govern the transport rate,
transformation, and fate of wastes are evaluated and
their mechanisms are described in mathematical
models. These, in turn, are evaluated through field
experiments and their applicability is demonstrated in
closure and/or corrective actions at hazardous waste
sites.
    Integrated, multimedia methods and data are being
developed by ERL/Athens for implementing waste
management decisions and evaluating waste manage-
ment, treatment, and disposal systems based on
potential human health and environmental impacts.
Probabilistic  techniques are developed and used to
address uncertainty. The various media models are
                                   46

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 Hazardous Waste
                           coupled to produce both screening-level and more site-
                           specific multimedia exposure assessment packages.
                              ERL/Corvallis is evaluating the biological hazard
                           associated with contaminated soils, water, and sedi-
                           ments and is determining the bioavailability (including
                           uptake, translocation, and metabolism) of hazardous
                           chemicals by plants and animals. Multimedia protocols
                           are being tested and field validated in various environ-
                           mental settings at waste and spill sites.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds ($K) In-House

                           ERL/DUL      Philip M. Cook    580.5     94.0
                           RSKERL/ADA  James F. McNabb 3,011.0     41.2
                           ERL/ATH      Rosemarie Russo  2,195.7     29.0
                           ERL/COR      Anne Fairbrother   316.6     67.2
                           OEPER/HQ     Will C. LaVeille   443.9     85.8
Scientific
Assessment
 Waste Characterization

    Chemical-specific health and environmental effects
documents are being prepared to support RCRA 3001
listing decisions. Support is also being provided to the
Office of Solid Waste (OSW) in the form of reference
dose documentation. Assessment methods are being
refined, such as microcomputer-assisted risk assess-
ment tools.
                          Office or
                          Laboratory

                          ECAO/CIN
                Contact

               Bruce Peirano
   Total     Percent
Funds ($K) In-House
   1,743
54.2
Modeling,
Monitoring Systems
and Quality
Assurance
Quality Assurance

    To ensure that the data on which regulations and
enforcement are based are accurate, quality control
(QC) samples will be provided to EPA contractor,
state, and local laboratories conducting RCRA monitor-
ing. Calibration standards will also be provided for
Appendix IX compounds to EPA contractor, state, and
local laboratories. Natural matrix, liquid, and solid
performance evaluation samples will be developed and

       47

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Hazardous Waste
                           distributed to RCRA contractors, EPA, and state
                           laboratories conducting RCRA hazardous waste
                           analyses. Performance evaluation (PE) materials that
                           contain the pollutants of interest at the levels encoun-
                           tered in the environment will be developed. Statistical
                           data on the laboratory evaluations will be reported to
                           the OSW. Referee laboratory analyses on all RCRA
                           samples will be conducted. Traceability to National
                           Institute for Standards and Technology for Performance
                           Evaluation (PE), Quality Control (QC), and method
                           validation study samples prepared for RCRA monitor-
                           ing activities  will be provided.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds($K) In-House

                           EMSIVCIN     William Budde     451.0     16
                           EMSL/LV      Eugene Meier      476.3     36
                           AREAL/RTP   William Mitchell    148.8     49
                           OMMSQA/HQ Ken Sala          300.0    100
Modeling,
Monitoring Systems
and Quality
Assurance
Releases

    In order to determine whether underground storage
tanks (UST) containing hazardous wastes are leaking,
evaluation of basic leak detection monitoring methods
for outside an UST will be conducted. This will
include: the establishment of candidate performance
criteria for several classes of monitoring techniques;
the development of test protocols for determination of
the performance criteria;  and testing of the "most
promising" leak detection methods to validate the test
procedure and to establish that instrumentation pres-
ently exists which can meet the candidate performance
criteria.
    Network design for the placement of leak detec-
tion devices will focus on the excavation zone around
tanks with emphasis on vapor monitoring. However,
monitoring in the saturated zone and in native soils
will also be considered.
    New technologies for leak detection monitoring,
such as fiber optics and geochemical sensors, will  be
evaluated. Methods for monitoring underground storage
tanks will be developed and validated, with emphasis
on monitoring during bioremediation, soil venting and
passive remediation.

       48

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Hazardous Waste
                              The Clean Water Act (Section 311) mandates that
                          Spill Prevention Control and Countermeasure (SPCC)
                          plans be prepared for all facilities engaged in the
                          production, storage, processing, and distribution of
                          hazardous materials. The Office of Modeling, Monitor-
                          ing Systems and Quality Assurance (OMMSQA)
                          provides remote sensing support. EPA regional offices
                          for SPCC surveys, planning and emergency response
                          activities.
                          Office or
                          Laboratory
                Contact
                          EMSL/LV      Eugene Meier
                          OMMSQA/HQ  Ken Sala
   Total     Percent
Funds($K) Iii-House

   1,444.6     26
Environmental
Processes and
Effects
Releases

    Within this activity, research is conducted to
address evaluation of cleanup techniques for unplanned
releases of hazardous wastes, i.e., the determination of
the applicability and cost-effectiveness of in-situ
reclamation techniques for unsaturated-zone and
ground-water contamination resulting from  leaking
underground storage tanks and other hazardous waste
sources.
    At RSKERL/Ada, coordinated laboratory and field
tests of biological, physical, and chemical methods,
previously tried at hazardous waste sites, are being
conducted to determine their cost and applicability to
cleanup of pollutants from leaking underground storage
tanks.
                          Office or
                          Laboratory
                Contact

RSKERL/ADA  James F. McNabb
   Total     Percent
Funds ($K) In-House
                                                           85.7    100
       Environmental
     Engineering and
          Technology
       Demonstration
Releases

    Underground storage tank (UST) research is
evaluating prevention, detection, and corrective action
technologies to identify cost-effective, reliable tech-
niques and equipment for USTs. Early work is produc-
ing state-of-the-art documents for each type of

       49

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Hazardous Waste
                            technology. The primary focus of ongoing work is
                            corrective action technologies and the targeting of high
                            potential technologies for improved performance. Best
                            engineering practices for leak prevention, the detection
                            of leaks, corrective action, and site cleanup will be
                            documented.
                            Office or
                            Laboratory

                            RREL/CIN
                            OEETD/HQ
                 Contact

               J. Farlow
               R. Nalesnik
   Total     Percent
Funds ($K) In-House
    967
      50
 50
100
 Modeling,
 Monitoring Systems
 and Quality
 Assurance
Waste Identification

    To improve procedures to characterize wastes for
listing under RCRA, research will be conducted to
develop methods for characterizing and detecting
particular wastes and providing criteria for determining
if those wastes constitute a potential hazard. The  lack
of standardized methods emphasizes the immediate
need for a comprehensive program to assure that  data
of known quality are being collected. Methods will be
tested for application to highly toxic wastes in soil and
sediments, for detection of organics in the ambient air
of waste disposal facilities, and for determining the
reactions of wastes in all media. Evaluation and
revisions of the analytical methods contained in the
SW-846 document are being conducted.
    Techniques for field monitoring of waste  sites will
be improved, including statistics for sampling design
and for sample handling. RCRA land disposal regula-
tions require the establishment of a groundwater
monitoring program at most facilities, including
detection and compliance of saturated and vadose zone
monitoring. Of particular importance is subsurface
monitoring of sites and investigation of new techniques
for monitoring soils, and biota, ambient air, and waste
incineration emissions. Methods will be developed to
detect trace metals in groundwater, ambient, and
sludges.
    Efforts will be directed toward validating waste
incinerator test methods for principle organic hazardous
constituents from waste incinerator stacks. Validated
methods for continuous monitoring of carbon  monox-
                                   50

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Hazardous  Waste
Environmental
Processes and
Effects
                          ide and hydrochloric acid emissions from incinerators
                          will be developed.

                          Office or                      Total     Percent
                          Laboratory      Contact     Funds($K) In-House

                          EMSL/CIN     William Budde     629.5     57
                          EMSL/LV      Eugene Meier    4,418.6     34
                          AREAL/RTP    William Mitchell   513.6     31
                          OMMSQA/HQ  Ken Sala
Development of Techniques and
Procedures to Prevent and Contain
Oil Spills

    This new activity reflects the concerns raised by
the recent major oil spills for means to evaluate the
various mitigation techniques and their potential
environmental consequences. Studies wUl be conducted
to provide the scientific data needed by regional staff
to choose the most cost-effective and environmentally
sound option for dealing with a spill. These options
will include technologies for removing oil, as well as
methodologies for determining the effectiveness of the
removal process.
    Other studies will develop restoration procedures
for oil-damaged marine, estuarine, freshwater, and
terrestrial ecosystems. Research will be conducted on
beach and shoreline remediation using chemical and
biological methods. Included will be process develop-
ment, field evaluations, and protocol development,
which will enable assessment of the ecological  impacts
of spills and of remediation alternatives.

Office or                      Total     Percent
Laboratory      Contact     Funds($K) In-House

ERL/ATH      Rosemarie Russo   136.2     16
ERL/GB       HapPritchard      146.3     21
                                 51

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Hazardous Waste
Environmental
Processes and
Effects
Develop Data to Support Treatment,
Storage, Disposal Regulations

    Direct technical support for site-specific issues will
be provided on an ad hoc basis to regional office staff
involved in RCRA corrective action activities. The
need is estimated to be equal to or larger than that
related to Superfund site cleanups. Based on the
successful Superfund assistance program now in place,
the effort will utilize the laboratory-based Technical
Support Centers (TSCs). Thus, TSC staffs at RSKERL-
Ada (ground water) and at ERL-Athens (exposure
modeling and ecorisk assessment) will become avail-
able to the regional RCRA Corrective Action pro-
grams. Extramural resources will be utilized to contract
on-site personnel to assist the TSC and its laboratory
in responding to the needs of RCRA staff. The TSCs
will also participate in an effort to transfer technical
information to the Corrective Action community
through a variety of means (e.g., documents, seminars,
videos).

Office or                      Total     Percent
Laboratory      Contact      Funds($K)  In-House

RSKERL/ADA  John E. Matthews  273.4     22.4
ERL/ATH     Rosemarie Russo   145.0     48.8
Scientific
Assessment
 Technology Transfer

    A pilot Technical Support Center in Health and
Risk Assessment will be initiated for the RCRA
Corrective Action Program.
                          Office or
                          Laboratory

                          ECAO/CIN
                Contact

               Bruce Peirano
  Total    Percent
Funds($K) In-House
    117
5.1
                                 52

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Hazardous Waste
Environmental
Engineering and
Technology
Demonstration
Oil Spills Research

    ORD is focusing its oil spills research program in
the following four areas:
    •   Bioremediation
    •   Dispersant Research
       Mechanical Cleanup of Inland Spills
    •   Debris Disposal
    In the bioremediation area, research will be
continued to develop protocols which can be used to
evaluate the efficacy and toxicity of bioremediation
agents under various spill scenarios. Once developed,
these protocols will be verified at spills of opportunity
or at research spills. Information on the products tested
will be made available to spill coordinators to allow
quick decisions to be made on the use of these
materials at the time of a spill. Research will also
continue to develop similar information on dispersants.
In addition, future research may be conducted to
determine the relative risk of dispersing the oil
throughout the water column vis-a-vis allowing it to
remain on  the surface and eventually ending up on
beaches, marshes, etc. Limited research is being
conducted  to develop containment  and cleanup equip-
ment for use on fast-flowing inland rivers and streams.
ORD will undertake research to evaluate alternative
disposal options for the debris which is normally
generated during cleanup operations following a major
oil spill.
                           Office or
                           Laboratory

                           RREL/CDSf
                           ERL/GB
                           ERL/ATH
                           HERL/RTP
                           OEETD/HQ
                Contact

               A. Venosa
               F. K. Pritchard
               J. Rogers
               L. Claxton
               K. Jakobson
  Total     Percent
Funds($K) In-Hou.se
   1,335
    550
    448
     80
     50
80
50
70
50
90
                                  53

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Toxic  Substances
Environmental
Processes and
Effects
Biotechnology

    The biotechnology research effort is concerned
with interactions between microorganisms and ecologi-
cal processes in an attempt to develop comprehensive
knowledge of the biochemical, physiological, and
genetic mechanisms involved. The program will
examine the potential environmental risk associated
with the application of Genetically Engineered Micro-
organisms (OEMs).
    Assessment of environmental impacts of OEMs
requires reliable methodologies for their identification
and enumeration in environmental samples. The
methods must address the analytical and operative
criteria required for any monitoring program. They
must be sensitive and specific to differentiate OEMs
from the background of indigenous organisms. They
have to be feasible, accurate, reproducible, and widely
applicable since samples will differ greatly from one
another, such as leaf surfaces and freshwater reser-
voirs.
    Contained aquatic and terrestrial laboratory
systems (microcosms) are used to assess the fate of
OEMs in various ecosystems. The fate of microbes in
microcosms is compared with fate in natural systems
to assess the validity of laboratory data.
    Research in this area applies techniques of
molecular and classical genetics to ecological studies
to assess survival and growth of novel microorganisms.
Questions of specific niche requirements, selective
advantages of new genotypes, and potential for causing
harmful effects to populations, ecosystems, or pro-
cesses will be examined. The research also addresses
genetic stability of altered microorganisms, including
transmissibility of plasmids and other genetic informa-
tion in situ.
                            Office or                        Total     Percent
                            Laboratory       Contact     Funds ($K) In-House

                            ERL/GB        Robert Menzer    1,695.2     13
                            ERL/COR      Thomas Murphy   1,644.1     16
                                   54

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Toxic  Substances
Environmental
Engineering and
Technology
Demonstration
Biotechnology/Microbial and Biochemical
Pest Control Agents

    This research program plan addresses the three
primary engineering-oriented research concerns posed
by the Office of Toxic Substances (OTS) in its
implementation of the Premanufacturing Notice
(PMN) process of the Toxic Substances Control Act
(TSCA):

    •   mechanisms of accidental or deliberate
       release of the modified genome or organism
       from the site of production (e.g., in effluents)
       and techniques for quantification;

    •   availability and effectiveness of containment
       controls or destruction techniques and
       appropriate validation methods; and

    •   sources and quantification of worker expo-
       sure, particularly due to aerosols.

    In order to satisfy these concerns, the program is
divided into two sub-programs. The first addresses
biologically-based manufacturing processes; the
second addresses  deliberate application to a specific
environmental area.
    Data bases are being developed for assisting with
the PMN review under  the first sub-program. These
will permit assessment of the occurrence, magnitude,
and degree of risk management (pollution prevention)
applicable  to deliberate  and accidental releases from
biologically based manufacturing processes. Models
are being developed along with an information base
which OTS will use as  a guide for identification of
potential hazards  and implementation of safeguards for
reduction of risk to acceptable levels.
    Because OEMs have already been developed for
applications requiring deliberate release into the
environment, the  second sub-program addresses the
development of procedures for assessing the safety
aspects of  the engineering techniques for introducing
these microorganisms into the environment. Informa-
tion to be developed will allow an assessment of the
risk of migration  from the site and of the management
techniques to prevent or. minimize this migration.

       55

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Toxic  Substances
                              A number of application techniques will be
                           addressed using scenarios appropriate to the environ-
                           ment likely to be encountered. Applications considered
                           for evaluation include: agricultural formulations;
                           pollutant clean-up and control (spills, landfills, con-
                           taminated sediments, oil spills); tertiary oil recovery;
                           in-situ mineral recovery (metals leaching, oil shale).
                              The engineering assessment protocols for release
                           and exposure will be structured to account for several
                           sets or combinations of various biological properties,
                           or subsets, and appropriate applications involving
                           deliberate environmental release. Further effon will be
                           devoted to identifying specific data (chemical, physi-
                           cal, and biological)  that will be required as inputs to
                           the engineering risk-assessment protocol so that data
                           can specifically be developed and submitted as part of
                           the PMN review procedures.
                           Office or
                           Laboratory

                           RREL/CIN
                           OEETD/HQ
                Contact

               John Burckle
               Marshall Dick
   Total     Percent
Funds ($K) Ill-House
    138.7
     25.0
15
75
Modeling,
Monitoring Systems
and Quality
Assurance
Biotechnology/Microbial and Biochemical
Pest Control Agents

    This research evaluates and standardizes sampling
methodology to identify and quantify release of
microorganisms or biotechnology products into the
environment. Standardized procedures are developed
and used to produce guidelines to assess human
exposure and environmental impact of OEMs release.
                           Office or
                           Laboratory
                Contact
   Total     Percent
Funds($K) In-House
                           EMSL/LV      Stephen Hem
                           OMMSQA/HQ  Laurie Schuda
                                286.8
              25
                                  56

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Toxic  Substances
Health Effects
Biotechnology/Microbial and Biochemical
Pest Control Agents

    Biotechnology research is aimed at the develop-
ment of methods to evaluate the potential health
hazards of genetically engineered organisms and the
products of these microorganisms. Potential mecha-
nisms of action and screening methods for adverse
mechanisms are being investigated. Models are being
developed to assess the potential dispersal capability of
genetically engineered genes.

Office or                       Total     Percent
Laboratory       Contact     Funds ($K) In-House

HERL/RTP     Elaine Grose        33
OHR/HQ       David Kleffman     469.1
Environmental
Processes and
Effects
Ecology: Ecotoxicity and Risk Assessment

    Environmental risk assessment studies on the
linkage of environmental exposure and ecotoxicology
hazard assessment techniques, and development of
methods to evaluate risks continues. The goal is to be
able to predict toxic risk to varied ecosystems and
components within acceptable limits of uncertainty.
    The ecotoxicology studies include the movement,
transformation and ultimate disposition of toxic
substances in all environmental media as a critical
component of risk assessment How plants and animals
or ecosystems and biological interactions are affected
by toxic substances are also the subjects of this
research effort.  Research goals include the identifica-
tion of important endpoints and development of
mathematical modeling techniques (population;
transport) to integrate data and depict risk. Input data
will include such results as lab to field comparative
responses, measurements of ecosystem resistance and
resilience, recovery, population changes (mortality;
feeding behavior), biota uptake and susceptibility.
Techniques such as quotient-based approaches at
various scales of system complexity and causative
factors affecting variations in toxicity data (taxonomic
considerations)  and modeling results will be studied.
The validated predictive tools and the results will be
                                   57

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Toxic  Substances
                           used in regulatory decision making and as a guide to
                           formulating regulatory criteria and standards.

                           Office or                        Total    Percent
                           Laboratory      Contact     Funds ($K) In-House

                           ERL/ATH      Rosemarie Russo   813.0     49
                           ERL/COR      Thomas Murphy     87.7    100
                           ERL/DUL      Oilman Veith      463.8     28
                           ERL/GB        Robert Menzer     100.0      0
                           ERL/NARR    Norbert Jaworski    37.2     33
Environmental
Processes and
Effects
Ecology: Transport/Fate/Field Validation

    This research encompasses the determination of
the effects, movement, transformation, and ultimate
disposition of toxic substances and their degradation
products that inadvertently enter into all environmental
media. This program provides information on how
plants and animals and larger ecosystems are affected
by exposure to toxic  substances caused by accidents in
commerce and industry. Specific activities include
developing and validating techniques for assessing
hazards, exposure and estimation of the fate of existing
chemicals through  lab, microcosm or field studies.
    Information developed in the above studies
provides data necessary for hazard and exposure
assessments and for designing mathematical models of
chemical transport, transformation and fate including
biodegradation. Research addresses such problem areas
as: intermedia transfer, characteristics of chemicals
(e.g., chemical kinetics/hydrolysis and  microbial rate
constants) and the  processes of the receiving environ-
ment; comparative lexicological responses; system
level effects (e.g., community alterations); effects of
toxicants on animal and plant development and applied
chemical structure-activity  techniques,  methods for
measuring ecosystem recovery and abiotic transforma-
tion. Research results help  the Agency to determine
potential adverse impacts of toxicants and to help
formulate preventative or remedial actions.
                                  58

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Toxic Substances
                          Office or                      Total    Percent
                          Laboratory      Contact    Funds ($K) In-House

                          ERL/ATH     Rosemarie Russo   893.7    100
                          ERL/GB       Robert Menzer     678.9    100
                          ERL/COR     Thomas Murphy    852.2    100
Modeling,
Monitoring Systems
and Quality
Assurance
Exposure Monitoring

    Research for exposure monitoring is dedicated to
development, testing, and standardizing monitoring
methods to estimate total human exposure and popula-
tion exposures. Human activity patterns are studied to
improve estimates of exposure. Human exposure data
are used to construct models to estimate an individual's
pollutant exposure in all media. Microenvironment
studies are conducted to fill data gaps.
                          Office or
                          Laboratory

                          EMSL/LV
                          AREAL/RTP
                          OMMSQA/HQ
                Contact

              Stephen Hern
              Dale Pahl
              Laurie Schuda
  Total     Percent
Funds($K) In-House
   1,294.9
    580.1
    249.2
45
20
Health Effects
Health: Markers, Dosimetry, and
Extrapolation

    This research is aimed at providing techniques to
reduce the uncertainties in risk assessments. Tech-
niques are needed to extrapolate between adverse
effects seen in animal species and human health effects
and between high doses used in animal toxicity testing
and low doses typical of environmental exposure.
Dosimetry models are being developed for oral,
dermal, and inhalation routes of exposure. Biological
markers research focuses on the development of
indicators of biological dose and resulting effects for
eventual application to studies of human populations.
                          Office or
                          Laboratory

                          HERL/RTP
                          OHR/HQ
                                 59
                              Total    Percent
                Contact    Funds ($K) In-House

              Elaine Grose     4,067.3     37
              David Kleffman

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Toxic  Substances
Modeling,
Monitoring Systems
and Quality
Assurance
Health: Markers, Dosimetry, and
Extrapolation

    This research evaluates physiological, biochemical,
genetic and immunologic techniques as indicators of
human exposure to chemical pollutants. Biomarkers are
tested for sensitivity, selectivity, and reliability to
indicate episodes of pollutant exposure.

Office or                      Total     Percent
Laboratory      Contact     Funds ($K) In-House

EMSL/LV       Stephen Hem      332.0    30
OMMSQA/HQ  Laurie Schuda      39.7
Health Effects
Special Human Data Needs

    This research is designed to provide information to
assist in identifying and regulating existing chemicals
with potential human health risks. Research focuses on
developing epidemiological and biostatistical methods.
Efforts in biochemical epidemiology are underway to
identify and evaluate biomonitoring and screening
methods for potential application to human environ-
mental epidemiology.
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                               Total     Percent
                Contact     Funds ($K) In-House
               Elaine Grose
               David Kleffman
1,461.0     23
 Environmental
 Processes and
 Effects
Structure Activity Relationships

    This research is designed to determine the disposi-
tion of new toxic chemicals in all environmental media
and to determine if selected plants and animals might
be affected. This involves developing structure-activity
relationships (SAR)  with methodologies based upon
molecular structure characteristics to rapidly assess the
environmental fate and toxicity of new chemicals.
Structure-activity develops those data bases and
mathematical models which are used for predicting
exposure, bioaccumulation, toxicity, fate, and other
parameters. Activities include the development of data
       60

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Toxic  Substances
                           bases on plant uptake, fate of organic chemicals,
                           toxicity to fish and reactivity of chemicals (e.g.,
                           photolytic, electrophilic, nucleophilic). Integrated into
                           this research is data on transport and transformation of
                           both organic and inorganic substances in freshwater
                           and multimedia environments and application of SAR
                           to predict effects of new chemicals on biota. The latter
                           includes determination of and predictions on toxic
                           mechanisms and microbial transformation and metabo-
                           lism. Expert systems are being applied to the SAR
                           approach. Computer based predictive  programs are in
                           use in regulatory evaluations.

                           Office or                       Total     Percent
                           Laboratory       Contact     Funds ($K) In-House

                           ERL/ATH      Rosemarie Russo   375.9    100
                           ERL/DUL      Oilman Veith       576.2     58
Health Effects
Structure Activity Relationships

    Methods are being developed to use combinations
of descriptions based on molecular structure to predict
enzymatic, genetic, carcinogenic, and other activities of
new chemicals to support Section 5 of the Toxic
Substances Control Act (TSCA). Techniques include
pattern recognition  and statistical and thermodynamic
analyses. In addition, chemical data bases are being
constructed for use in predicting lexicological re-
sponses for new chemicals with similar structures.
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                Contact
   Total     Percent
Funds ($K) In-House
               Elaine Grose
               David Kleffman
    777.7
56
Scientific
Assessment
Emergency Planning and Community Right
to Know

    In support of the Superfund Amendments and
Reauthorization Act (SARA) Title III, Section 313, the
scientific assessment program prepares profiles and
incorporates them into the Integrated Risk Information
System (IRIS) to provide information to various
       61

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Toxic  Substances
                         governmental agencies and the public on the health
                         effects of chemicals released into the environment.
                         Office or
                         Laboratory

                         OHEA/HQ
               Contact

              Hugh McKinnon
  Total    Percent
Funds ($K) In-House
     50.0
 0
Modeling,
Monitoring Systems
and Quality
Assurance
Emergency Planning and Community Right
to Know

   Research is conducted to identify methods to
detect release of chemicals on the SARA Title m list
into the environment and to develop human exposure
monitoring procedures to assess human exposure to
chemicals released from these installations.
                         Office or
                         Laboratory
               Contact
   Total    Percent
Funds($K) In-House
                         EMSL/CIN     John Winter
                         OMMSQA/HQ  Laurie Schuda
                              323.8
                               44.6
             20
Environmental
Engineering and
Technology
Demonstration
Emergency Planning and Community Right
to Know

   In support of SARA Title III, Section 313,
research, in cooperation with industrial trade associa-
tions, is being conducted that will improve the accu-
racy of release estimations for the Toxic Release
Inventory (TRI) reporting. Current work is concentrat-
ing on the difficult-to-estimate releases from welding
processes and electroplating and surface finishing
industries.
                         Laboratory

                         RREL/CIN
                         OEETD/HQ
               Contact

              Roger Wilmoth
              Marshall Dick
   Total    Percent
Funds ($K) In-House
    174
10
                               62

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Toxic Substances
Scientific
Assessment
Support for Toxic Substances Control Act
(TSCA)

   The scientific assessment program provides
support to the Office of Toxic Substances in the area
of assessments of cancer, mutagenicity, adverse
reproductive/developmental effects, and exposure.
These activities support decision making under TSCA
(i.e., existing chemicals, PMN review, and test guide-
lines and test rules development).
                         Office or
                         Laboratory

                         OHEA/HQ
               Contact

              Hugh McKinnon
   Total     Percent
Funds ($K) Ill-House
    178.2    100.0
Modeling,
Monitoring Systems
and Quality
Assurance
Support for Toxic Substances Control Act
(TSCA)

    Quality assurance research is conducted to support
routine monitoring and assessment Studies are under-
way to evaluate exposure models and the use of
computer aided technology to estimate exposure and
risk. Reference chemicals and analytical spectra for
chemical compound identification are produced to
provide standardization procedures and guidelines for
program office field studies.
                         Office or
                         Laboratory

                         EMSL/CIN
                         EMSL/LV
                         OMMSQA/HQ
               Contact

              John Winter
              Stephen Hern
              Laurie Schuda
   Total     Percent
Funds($K) In-House
    345.1
    273.6
     86.6
20
35
Environmental
Engineering and
Technology
Demonstration
Engineering

    This program supports the Office of Toxic
Substances (OTS) in its implementation of the TSCA,
Asbestos Hazard Emergency Response Act (AHERA),
and Title III of SARA. The program focuses on the
development of predictive capabilities to be used in
assessing release and exposure levels for the review of
PMNs for new chemicals, and the techniques and
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Toxic Substances
                             controls for ensuring "no risk" exposure to existing
                             chemicals.
                                The "new chemicals" sub-program  is evaluating
                             the manufacturing and processing of these chemicals
                             from both the unit operations and "an industrial-
                             setting" perspective. Research in the operations area
                             has focused on drying and filtration equipment, with
                             attention to the mechanistic relationships to toxic
                             particulates and their control. Emphasis has been
                             placed on the frequency of exposure and the  magni-
                             tude and duration of inhalation and dermal exposure
                             levels in the work place. Additional emphasis has been
                             directed toward simulating the "real-world" environ-
                             ment
                                Research in the industrial-settings area has been
                             concentrated on those manufacturing scenarios found in
                             the polymer processing industry. Emphasis has been
                             directed toward exposures associated with the off-
                             gassing of monomers, degradation products, and
                             polymer additives.
                                As the program matures, increased  interaction is
                             available in "pollution prevention" contexts, where data
                             from Toxic Release Inventory (TRI) estimates can be
                             integrated with control strategies to reduce pollutant
                             generation and worker exposure.
                                In the fate assessment subprogram, emphasis has
                             been placed on water  soluble compounds which
                             ultimately are subjected to secondary wastewater
                             treatment, and in particular, activated sludge  treatment.
                             Based on  the high numbers of azo-dye  PMN submis-
                             sions, these dyes remain a priority for investigation.
                                In the past, agency  guidance for asbestos in
                             buildings  has been developed from the  best-engineer-
                             ing judgment concept Research is continuing to
                             evaluate the effectiveness of current guidance which
                             includes removal, and in situations where the asbestos-
                             containing materials is to be left in place, operations
                             and maintenance procedures. Current efforts  are
                             stressing evaluations of  maintenance practices for vinyl
                             asbestos tile floors.
                                To satisfy the needs of AHERA, efforts  will be
                             expanded to evaluate  transportation and disposal
                             options, in addition to attempting to indicate the
                             "least-burdensome" strategy when several "risk-free"
                             options are available.  Over the next three years, the
                             program will shift toward developing cost-effective
                             removal/containment technologies and addressing the
                                    64

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Toxic Substances
                          broader area of controlling all harmful respirable and
                          durable fibers.
                          Office or
                          Laboratory

                          RREL/CIN
                          OEETD/HQ
                Contact

              Roger Wilmoth
              Marshall Dick
   Total     Percent
Funds ($K) In-House
   1375.0
    108
25
75
Modeling,
Monitoring Systems
and Quality
Assurance
Test Method Development

    Test method development research is conducted to
improve procedures to identify and quanu'tate chemical
compounds of interest. Emphasis is placed on develop-
ment of biological and chemical procedures to measure
chemicals in different media including biological
monitoring and immunochemical procedures. New
statistical techniques are developed for spectra analysis
                          Office or
                          Laboratory

                          EMSL/LV
                          AREAL/RTP
                          OMMSQA/HQ
                Contact

               Stephen Hem
               DalePahl
               Laurie Schuda
   total     Percent
 Funds($K) In-House
     607.2
     200.4
      30.0
45
25
Environmental
Processes and
Effects
Test Method Development

    To assess environmental hazards, research focuses
on developing, improving and validating single and
multi-species toxicity tests for chronic and acute
toxicity in aquatic ecosystems. The developed methods
support development of testing guidelines for TSCA
and provide basic data  for determining exposure and
appropriate endpoints that can be related to real-world
situations.
    Test methods development for aquatic biota
provides new or modified bioassays which support
lexicological evaluations and toxicokinetic models on
such concerns as uptake from contaminated sediments,
extrapolations from species to species and determining
carcinogenic potentials  of chemicals.
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Toxic Substances
                          Office or
                          Laboratory

                          ERL/DUL
                          ERL/GB
                          OEPER/HQ
                Contact

              Oilman Veith
              Robert Menzer
              Steve Cordle
   Total     Percent
Funds ($K) In-House
    164.8
    214.2
    583.5
100
100
 66
Health Effects
Test Method Development

    Under the TSCA, EPA must provide industry with
guidance to test chemicals for potential hazards to
public health. In order to base regulatory decisions on
the best possible data, reliable test methods must be
developed for incorporation into test guidelines. The
goal of this research is to develop short-term, cost-
effective, predictive methods for detecting the toxic
effects of chemicals. These test systems include both
in vitro and in vivo methods and bioassays for-
predicling adverse health effects such as alterations in
reproductive and developmental processes and
immunotoxic and neurotoxic effects.
                          Office or
                          Laboratory

                          HERL/RTP
                          OHR/HQ
                              Total     Percent
                Contact    Funds ($K) In-House
              Elaine Grose      1842.6
              David Kleffman
             53
Modeling,
Monitoring Systems
and Quality
Assurance
Asbestos

    Research is being conducted to develop and
evaluate monitoring procedures to determine human
and environmental exposure to asbestos, refractory
ceramic fibers (RCFs), and other asbestos substitute
fibers in selected microenvironments.
                          Office or
                          Laboratory

                          AREAL/RTP
                          OMMSQA/HQ
                Contact

              Dale Pahl
              Laurie Schuda
   Total     Percent
 Funds(SK) In-House
    507.3
     80.7
 10
                                 66

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 Pesticides
Environmental
Processes and
Effects
 Biotechnology/Microbial and Biochemical
 Pest Control Agents

    This portion of the research program is planned to
 develop or improve bioassay methodologies for
 determining the effects of biological control agents or
 biochemical agents (e.g., hormones, pheromones) on
 non-target biotic receptors. The application of the
 methods assists in establishing testing guidelines and in
 registering and controlling the use of these control
 agents. Agents of interest include both genetically
 altered and unaltered bacteria, viruses and fungi.
 Parameters to be studied include routes of exposure,
 methods to recover or identify the agents and to
 estimate virulence, toxicity and infectivity. Survival,
 growth, persistence and effects plus controlling abiotic
 factors are of concern. Generic transfer and stability
 associated with OEMs will be investigated. Special
 handling and monitoring methods and systems will be
 studied. Novel control procedures for pesticide applica-
 tions using microbial regulation are being studied. All
 extramural monies will be expended by the laboratories
 subsequent to final planning actions.

 Office or                        Total      Percent
 Laboratory       Contact     Funds ($K) In-House

 ERL/COR      Thomas A. Murphy 543.4     46
 ERL/DUL      Oilman Veith       358.9     28
 ERL/GB        Robert Menzer    1,170.6     53
Health Effects
Biotechnology/Microbial and Biochemical
Pest Control Agents

    Models will continue to be developed on potential
interaction of microbial agents and the mammalian
cell. Goals are (1) the determination of the ability of
microbial agents to replicate in mammalian cells, and
(2) to provoke immune responses in non-target
(mammalian) hosts. Methods will also be developed to
identify genetic material from microbial pesticides in
non-target sites such as mammalian cells in vitro and
in vivo. Research will also focus on the effects of
genetically engineered pesticides on mammalian
organisms.
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Pesticides
                              Research in this area is also aimed at the develop-
                           ment of methods to evaluate the potential health
                           hazards of genetically engineered organisms and the
                           products of these microorganisms. Potential mecha-
                           nisms of action and screening methods for adverse
                           mechanisms are being investigated. Models are being
                           developed to assess the potential dispersal capability of
                           genetically engineered genes.
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                               Total     Percent
                Contact     Funds ($K) In-House
               Elaine Grose
               David Kleffman
    578.8
50
Scientific
Assessment
Support for Federal Insecticide, Fungicide
and Rodenticide Act (FIFRA) Activities

    The scientific assessment program provides
support to the Office of Pesticide Programs in the area
of assessments of cancer, mutagenicity, adverse
reproductive/developmental effects, and exposure.
Support is also provided on a case-by-case basis with
laboratory data audits.
                           Office or
                           Laboratory

                           OHEA/HQ
                Contact

               Hugh McKinnon
   Total     Percent
Funds ($K) In-House
    198.6    100
Modeling,
Monitoring Systems
and Quality
Assurance
Support for Federal Insecticide, Fungicide
and Rodenticide Act (FIFRA) Activities

    The pesticides quality assurance program ensures
the accuracy of the data which is attained through
testing and analysis. The program conducts quality
assurance research and supports the management of the
operation of the Pesticide Repository which supplies
pesticide compounds and metabolites. Federal and
State laboratories use these samples as standard
reference for internal quality control. Research is
conducted to develop procedures to ensure quality
control in environmental monitoring studies and
analysis of samples for pesticide residues. Efforts will
                                  68

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Pesticides
                           be continued in FY92 to assess the merits of
                           privatizing the Pesticide Repository.
                           Office or
                           Laboratory
                Contact
  Total     Percent
Funds($K)  In-House
                           EMSL/CIN     John Winter
                            OMMSQA/HQ Laurie Schuda
                                 287.5
                                  27.2
               0
Environmental
Processes and
Effects
Ecology: Ecotoxicity and Risk Assessment

    To register or re-register pesticides it is necessary
to develop a focused risk assessment process for
integrating hazard and exposure assessments to
estimate the probability of risk to important non-human
populations. This facet of the research program
develops environmental risk assessment methodology
by combining impact data using existing or new
models to express risk as a probability with estimates
of the associated uncertainty.
    New endpoint responses will be studied encom-
passing ecosystem structures and function. Selected
wildlife and microbial populations will be used to
reflect population changes and other changes that
influence risk evaluations. Other parameters that affect
model integrity will be studied (e.g., species suscepti-
bility, chemical routes of exposure, and uptake and
residues). Modeling will be supported through data
integration and model calibration and validation will be
supported through field studies that include all media.
A pesticide ranking index and registry system is being
developed as a tool for assessing selected aquatic
systems.

Office or                       Total     Percent
Laboratory       Contact     Funds ($K) In-House

ERL/ATH      Rosemarie Russo   394.7       0
ERL/COR      Thomas Murphy    766.7       9
ERL/DUL      Oilman Veith      429.0     29
ERL/GB        Robert Menzer     360.0       0
ERL/NARR     Norbert Jaworski    45.0       0
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Pesticides
Environmental
Processes and
Effects
Ecology: Transport/Fate/Field Validation

    Research will concentrate on the development,
refinement and validation of techniques and models to
measure and predict pesticide transport, degradation,
exposure, effects, and fate in the environment Labora-
tory and field studies will be conducted to substantiate
the applicability of methods and mathematical models
and to determine if results are valid and reflect
environmental responses under natural conditions. Data
from these studies will be used  to assess pesticide
hazards to surrogate species, populations, and commu-
nities representative of aquatic (i.e., estuarine) and
terrestrial habitats.
        These  investigations will include analysis of
abiotic influences on study results and on various
chemical and physical factors and processes. Sorption,
leaching and bioaccumulation will be evaluated.
Ground water contamination and associated processes
will be explored and remedial actions sought. Informa-
tion systems will be developed and used to help
implement management strategies  to prevent pesticide
contamination of ground water.  Predictive techniques
for exposure assessment technology will be improved
with studies on pesticide sorption kinetics, transforma-
tions, structure reactivity correlations and mechanisms
of degradation. Terrestrial ecotoxicology studies will
include development of data and methods to assess and
predict stress impacts on wildlife (e.g., bird) popula-
tions including comparability between lab and field
tests.
    Information and data including assessments and
predictive tools, evaluations of assessment criteria,
models and user manuals, workshops and reviews are
applied to support the Agency's regulatory actions.

Office or                         Total     Percent
Laboratory       Contact    Funds ($K) In-House

ERL/ATH      Rosemarie Russo   694.4     55
ERL/COR      Thomas Murphy    589.6     32
ERL/DUL      Oilman Veith       496.7     62
ERL/GB       Robert Menzer    1,007.2     81
OEPER/HQ      Steve Cordle       582.4     66
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Pesticides
Environmental
Engineering and
Technology
Demonstration
Engineering

    This program, which supports the Office of
Pesticide Programs (OPP), previously consisted of two
major areas: protective clothing and disposal technol-
ogy. The protective clothing research is concluding and
will provide a "Guidance Manual for Selecting
Protective Clothing for Agricultural Pesticide Opera-
tions." This manual will serve as a reference document
for OPP to use in protective-clothing issues related to
OPP's regulatory and training activities. This manual
will include standard test methods and performance
data from both laboratory and field tests. Work on
protective clothing has been phased out
    OEETD will continue to evaluate existing  disposal
techniques and processes for destroying specific
pesticide classes, develop a treatability database
applicable to pesticides and their disposal, and  develop
improved container reuse technology including a test
method to ensure compliance with existing regulations.
A major effort in this area, in conjunction with OPTS,
is evaluation of the effect of "burning" pesticide bags.
OEETD's intent in this area is  to provide technology
to minimize both worker exposure and pesticide/
herbicide disposal  to the environment by enhancing
handling, transfer, rinsing, and  treatment  protocols to
reduce accidental loss of the chemical.
                            Office or
                            Laboratory

                            RREL/CIN
                            OEETD/HQ
                 Contact

               Glenn Shaul
               Marshall Dick
   Total     Percent
Funds ($K) In-House
    265.9
      10.0
60
75
Modeling,
Monitoring Systems
and Quality
Assurance
Exposure Monitoring

    A coordinated research program is underway to
develop and evaluate methods to determine the
residues, fate and transport of pesticides in the residen-
tial environment, and the potential levels of human
exposure associated with their use. A primary focus is
validating methods for assessing exposure of infants
and small children to household pesticides, including
lawn care pesticides, both inside residences (via track-
in to carpets and other indoor surfaces) and in yards
and gardens. Factors to be investigated include the

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Pesticides
                           transfer of chemicals from surfaces to skin, bioavail-
                           ability of chemicals, and human activity patterns.
                               Research is also being conducted to develop and
                           conduct field validations of cost-effective and rapid
                           pesticide-specific immunochemical methods such as
                           immunoassays, and immunoaffinity Personal Exposure
                           Monitoring (PEM) devices for measuring pesticide
                           residues.
                           Office or
                           Laboratory

                           AREAL/RTP
                           EMSL/LV
                           OMMSQA/HQ
                 Contact

               Dale Pahl
               Stephen Hern
               Laurie Schuda
  Total     Percent
Funds($K)  In-House
    622.6
    592.4
    148.7
 5
15
Health Effects
Health: Markers, Dosimetry, and
Extrapolation

    This research focuses on developing animal
models to assess health risks and improve methodology
for extrapolating results of animal toxicity studies into
risk estimates for humans. Studies include evaluation
of interspecies differences in the dermal absorption of
pesticides, examination of structure-activity relation-
ships, examination of metabolic differences between
species which may contribute to teratogenic outcomes,
and the investigation of potential interactions between
alterations in maternal health status and susceptibility
to pesticide exposures.
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                               Total     Percent
                 Contact     Funds ($K) In-House
               Elaine Grose
               David Kleffman
    842.1
66
Environmental
Processes and
Effects
Test Method Development

    Laboratory studies will develop, improve and
validate bioassay methodologies to be used as stan-
dardized pesticide testing protocols for aquatic organ-
isms. Various methods will be geared to testing chosen
life stages of endemic fishes and crustaceans or
surrogate test species for long-term or short-term
       72

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Pesticides
                            durations. These methods will help assess both expo-
                            sure and effects (e.g., metabolic, mortality or terato-
                            genic response) to pesticides and pesticide ingredients
                            under acute and chronic conditions and some may be
                            used for monitoring particular pesticides or sensitive
                            biota and for predicting response. Influencing environ-
                            mental factors which may modify testing results will
                            be studied to establish confidence limits for the
                            methods under given conditions. The methods will
                            contribute  to establishment of early detection of
                            hazards, provide sensitive, rapid and inexpensive
                            evaluation techniques, and provide testing protocols
                            that may be recommended to industry for testing their
                            products to comply with FTFRA requirements.
                            Laboratory

                            ERL/GB
                 Contact

               Robert Menzer
   Total     Percent
Funds ($K) In-House

     359.4    100
Health Effects
Test Method Development

     This research involves developing and refining
bioassays for the detection of adverse alterations in the
development of reproductive processes in animals
which allow for more accurate evaluations of reproduc-
tive development and function. Techniques are also
being developed, validated, refined and implemented
for determining human genetic effects caused by
exposure to chemicals. Additionally, methods are being
developed to determine the neurotoxicity and
immunotoxicity of pesticides.
                            Office or
                            Laboratory

                            HERL/RTP
                            OHR/HQ
                                Total     Percent
                 Contact     Funds ($K) In-House
               Elaine Grose
               David Kleffman
   2,895.0     46
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                           National Health and Nutrition Examination
                           Survey (NHANES-III)

Health Effects               The third National Health and Nutrition Examina-
                           tion Survey (NHANES-III) is one of a series of
                           surveys conducted by the National Center for Health
                           Statistics (NCHS) for the purpose of producing vital
                           and health statistics for the United States. Six
                           NHANES studies have been completed since 1960.
                           NHANES-III will be conducted for six years, from
                           1988-1994. During this time, approximately 40,000
                           Americans  aged 2 months and over will be randomly
                           selected from households, interviewed and invited to
                           participate in medical examinations at mobile examina-
                           tion centers. Approximately 30,000 individuals will
                           undergo the medical examination, which  includes a
                           physical examination and diagnostic and biochemical
                           testing. The sample is a statistically representative
                           sample of Americans with oversampling of the very
                           young, the  elderly, Blacks and Hispanics.
                               Some of the topics to be studied in NHANES-III
                           are nutrition status monitoring, osteoporosis, arthritis,
                           respiratory  and cardiovascular disease,  diabetes,
                           gallstone disease, AIDS, kidney disease, and growth
                           and development of children.
                               Research and public health  goals include the
                           following: (1) estimating the prevalence of disease and
                           risk factors, (2) estimating the incidence of certain
                           diseases, (3) estimating the prevalence  of functional
                           impairment, (4) providing population reference distri-
                           butions of health characteristics including growth and
                           development, (5) monitoring secular changes in
                           diseases and risk factors, and (6) identifying new risk
                           factors for  disease and reasons for secular trends in
                           health. EPA and other Federal agencies have collabo-
                           rated with NCHS in previous NHANES studies and in
                           NHANES-III.
                               EPA has participated in the planning of NHANES-
                           III and has funded two specific research areas; neuro-
                           toxic disorders and pulmonary function.

                           Office or                        Total     Percent
                           Laboratory       Contact     Funds ($K) In-House

                           HERL/RTP
                           OHR/HQ       Susan Perlin        565       12

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Health Effects
Research to Improve Health Risk
Assessment (RIHRA) (Health)

    The Environmental Protection Agency relies on
quantitative risk assessments of human health effects to
guide the regulatory decision-making process in
carrying out the mandates given to EPA under existing
environmental legislation. The utility of the risk-based
decision making process is dependent upon the
accuracy of available effects data and on our ability to
extrapolate this information to man. In situations where
the scientific data are insufficient, the risk manager is
presented with a broad range of possible risks upon
which to base his decision. This uncertainty has
significant impacts and ramifications for the regulatory
process in terms of balancing human health risks
against other societal needs.
    The primary objective of the RIHRA program is to
perform systematic and integrated research to improve
the scientific basis supporting health risk assessments.
Emphasis is being placed on addressing  the significant
uncertainties inherent in  the risk assessment process.
This program will provide critical information on the
relationship between exposure (applied dose), dose to
target tissue (delivered dose), and associated health
effects. Both laboratory and field research will be
conducted that will improve our understanding of basic
biological mechanisms, especially as it relates from
one set of circumstances to another. Research will
address four major areas: (1) Analysis of Uncertainty
in Risk Assessments, (2) Integrated Exposure Assess-
ment, (3) Physiologically Based Pharmacokinetic
Models, and (4) Biologically Based Dose-Response
Models.

Office or                        Total    Present
Laboratory      Contact     Funds  ($K) In-House

HERL/RTP     John Vandenberg  6320.6      5
OHR/HQ       Tom Miller
Exploratory
Research
Exploratory Research Grants

    The Research Grants Program supports research
initiated by individual investigators in areas of priority
interest to the Agency. Research proposals are solicited
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                            via two mechanisms: (1) the "Solicitation for Research
                            Proposals" which is published each year and invites
                            proposals in broadly defined areas of environmental
                            science and engineering, and (2) the Request for
                            Applications (RFA) which is a more targeted solicita-
                            tion mechanism which requests proposals in well-
                            defined areas of particular interest to the Agency. All
                            proposals received in response to either mechanism are
                            subjected to a rigorous peer panel review.  Areas in
                            which research proposals will be requested in FY 1992
                            under the general solicitation include: environmental
                            biology, environmental health, environmental engineer-
                            ing, environmental chemistry and physics, and
                            socioeconomics.
                                In an effort to provide more support to minority
                            institutions for the conduct of basic environmental
                            research, the Research Giants Program makes available
                            pre-application assistance for minority faculty at
                            Historically Black Colleges and Universities (HBCU)
                            and members of the Hispanic Association  of Colleges
                            and Universities (HACU) through its Minority Institu-
                            tions Assistance Program. Whether or not  this assis-
                            tance is  used,  however, research proposals received
                            under this program are reviewed along with proposals
                            received under the general solicitation and in accor-
                            dance with the standards applied thereunder.

                            Office or                        Total     Percent
                            Laboratory       Contact      Funds ($K) In-House

                            OER/HQ       Roger Cortesi    22,741        0
                            Exploratory Research Centers

Exploratory                  The purpose of the Exploratory Research Centers
Research                 Program is to provide dedicated support over several
                            years to fundamental, multidisciplinary research in
                            topics of interest to the environmental community. The
                            first solicitation in 1980 resulted in eight such research
                            centers. These centers were established between 1980
                            and 1981 and have operated continuously since then.
                            The eight original  centers are  currently being phased
                            out A solicitation  to establish four new centers funded
                            at $1.0 million  per year, was published in the spring of
                            1990. The new centers will begin operations in FY

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                            1992. Seven of the eight original centers will be
                            terminated in FY 1992 while the remaining one at
                            Louisiana State University will be terminated in FY
                            1993. The eight original centers are:
                               Industrial  Waste Elimination Center (Illinois
                            Institute of Technology)—studies innovative technology
                            and process modification to reduce industrial pollutants
                               Intermedia Transport Research Center (University
                            of California at Los Angeles)—defines chemical and
                            physical processes governing pollutant exchange at air-
                            land and air-water boundaries
                               Ecosystems Research Center (Cornell Univer-
                            sity)—identifies and applies ecosystem principles to
                            environmental  management problems
                               Marine Sciences Research Center (University of
                            Rhode Island)—assesses marine ecosystems health,
                            emphasizing exposure of marine organisms to toxics
                               Advanced  Control Technology Research Center
                            (University of Illinois)—studies separation technology,
                            thermal destruction, biological separation, and chemical
                            detoxification
                               Ground Water Research Center (Rice University,
                            Oklahoma State University, and the University of
                            Oklahoma)—studies subsurface characterization,
                            transport and fate, and ground water horizon modeling
                               Environmental Epidemiology Research Center
                            (University of Pittsburgh)—studies basic epidemiology
                            methods and airborne paniculate health effects studies
                               Hazardous Waste Research Center (Louisiana
                            State University)—conducts research to develop
                            advanced technologies for the destruction, detoxifica-
                            tion, recovery, or containment of hazardous wastes
                            Office or
                            Laboratory

                            OER/HQ
                 Contact

               Roger Cortesi
   Total     Percent
Funds ($K) In-House
   4,498
0
Environmental
Engineering and
Technology
Demonstration
Pollution Prevention

    The core research program for pollution prevention
focuses on development of information sources,
educational development and training; integration of
pollution prevention into permit writing and enforce-
ment settlements; development of pollution prevention
strategies for small and medium scale community
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                          planning; development of pollution prevention imple-
                          mentation strategies for the industrial and municipal
                          sectors; and on identifying opportunities for pollution
                          prevention in the agriculture sector. Comparative risk
                          assessments are being conducted on several consumer
                          products from design through disposal.
                          Office or
                          Laboratory

                          OEETD/HQ
                          RREL/CIN
                          AEERL/RTP
                          OPPE/HQ
                Contact

              G. Ondich
              H. Freeman
              E. Shaver
              D. Allen
   Total     Percent
Funds ($K) In-Housc
   1,200
    700
   1,400
    294
0
0
0
0
Environmental
Engineering and
Technology
Demonstration
Socioeconomic Research

    The socioeconomic research program is being
implemented to augment the traditional command and
control approach to environmental problems. Rather
than depending on regulatory programs, the socioeco-
nomic approach utilizes information and communica-
tion methods. For many of the recently identified
environmental problems (radon, global climate change,
non-point sources, etc.), a socioeconomic approach to a
solution is much more likely to succeed than a
regulatory approach. In some cases, a regulatory
approach is just not feasible. Socioeconomic research
under this program will be conducted in the following
broad areas: risk communication, incentives and
disincentives, technical information dissemination,
commercialization and utilization, and education and
training.
                          Office or
                          Laboratory

                          OPPE/HQ
                Contact

               D. Allen
   Total     Percent
Funds ($K) In-House
    542
0
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Modeling,
Monitoring Systems
and Quality
Assurance

and

Health Effects
Total Human Exposure

    At present, EPA lacks information on human
exposure to virtually all chemicals of critical impor-
tance to  public health. Knowing the number of people
exposed and their level of exposure is essential for
estimating risk. Without this knowledge, it is currently
impossible to make adequate risk assessments, nor can
we prioritize the major sources and pathways of
exposure. This new long-term program is aimed at
developing an exposure data base to serve as a
foundation for exposure assessment, and, consequently,
risk management strategies.
    The goal is to measure and predict human expo-
sures and assess trends in human exposure to chemi-
cals of importance to the Agency. Specific objectives
include:  (1) developing methodologies for exposure
measurement and modeling, (2) characterizing repre-
sentative microenvironments on a national scale, (3)
defining regional and nationwide activity patterns, (4)
measuring exposure and body burden directly in field
studies, (5) determining the major sources of exposure
including air, drinking water, and food -  and their
contribution to risk, (6) developing and validating
exposure models and exposure-dose relationships, (7)
providing a comprehensive national data  base on
exposure for use of the Agency and the environmental
community, (8) monitoring nationwide trends and
regional  differences in human exposure and activity
patterns, and (9) assessing the effectiveness of regula-
tions by  observing these trends in total exposure.
    Initially, this program will stress five major areas:
(1) measurement methods development for personal
monitoring and microenvironmental characterization,
(2) chemical characterization  of representative micro-
environments (air, food, soil, water), (3) documentation
of human activity patterns, (4) development and
validation of predictive exposure models, and (S) direct
measurement of exposure  to validate models. In
addition, work will be initiated to develop and imple-
ment a pilot monitoring project leading to a nationwide
status and trends program.
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                      Office or                  Total    Percent
                      Laboratory     Contact     Funds($K) In-House

                      AREAL/RTP  Gerald Akland   2,485.4    24.0
                      EMSL/LV    Gareth Pearson  1,018.1    14.0
                      EMSL/CIN    AlDufour/       431.2     2.3
                                 Maurice Berry
                      OMMSQA/HQ Chris Saint       316.8    21.5
                      OHR/HQ     Tom Miller     2,000.0     0
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Environmental
Processes and
Effects
China Program

    This research program, which is conducted under
the  1980 US-PRC Environmental Protection Protocol,
studies the relationship of lung cancer and indoor coal
smoke pollution in a rural setting and children's
respiratory health across a wide gradient of paniculate,
acid, and sulfur oxide exposures in several Chinese
cities. Research is also continuing on environmental
processes and effects of pollution on aquatic organ-
isms, ground water and water pollution fate  and
transport models.
                          Office or                       Total     Percent
                          Laboratory      Contact     Funds ($K) In-House

                          AREAL/RTP   William Wilson    180.0     0
                          ERL/ADA      BertBledsoe       20.0     0
                          ERL/ATH      Rosemarie Russo    90.0     0
                          ERL/DUL      Nelson Thomas     25.0     0
                          HERL/RTP     Robert Chapman   196.7     0
                          OEPER/HQ    ChiehWu           6.8     0
                          ERL/NARR    Norbert Jaworski    25.1     0
Health Effects
Harvard Study

    This research program identifies and selects post-
doctoral research fellows and visiting scientists to work
with Harvard faculty members on research projects that
address critical environmental problems that face
society.
                          Office or
                          Laboratory

                          HERL/RTP
                          OHR/HQ
                              Total     Percent
                Contact    Funds ($K) In-House
              David Kleffman    250
Risk Assessment
Forum
Consistent Risk Assessment

    Risk Assessment Forum—The Forum, a group of
senior scientists, meets regularly to promote consensus
on risk assessment issues and to ensure that this
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                           ment guidance. The Forum undertakes projects de-
                           signed to resolve difficult issues raised (and incom-
                           pletely resolved) during guideline development.
                           Activities include sponsorship of workshops, colloquia,
                           and other meetings to discuss controversial risk
                           assessment issues.
                           Office or
                           Laboratory

                           AA/ORD
                           Forum
                               Total     Percent
                Contact     Funds ($K) In-House
               Dorothy Patton     701.8     80.4
Scientific
Assessment
Lead Abatement

    Lead continues to be one of the most serious
public health problems in the U.S. In response to this
problem, the Agency will: 1) take regulatory actions to
set/revise lead standards to adequately protect public
health, 2) carry out effective enforcement/abatement
activities to reduce exposure from lead-based paint,
soil, water, air, and other relevant media, and 3)
identify ways to reduce commercial uses of lead and
disposal of lead-contaminated wastes. Multi-media
research will be conducted to support regulatory,
enforcement, and abatement  efforts across all EPA
program offices. Research will be conducted in: direct
abatement support, exposure analysis/measurement,
health implications, and technology transfer.
                           Office or
                           Laboratory

                           ECAO/RTP
                Contact

               Lester Grant
   Total     Percent
Funds ($K) In-House
   2,405.2
7.5
Modeling,
Monitoring Systems
and Quality
Assurance
Development, Validation, and
Standardization of Analytical Methods in
Support of Regional Programs

    This research is targeted at specific areas that have
been identified as regional analytical support needs.
The program is working closely with the regions to set
priorities within and among these specific areas. Based
on comprehensive review  of regional needs, a work
plan has been developed and has initiated research in
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                            the following high priority areas: 1) low level meth-
                            ods and reference materials for nutrients, volatile and
                            semi-volatile organics, and metals in all media, 2)
                            digestion techniques for metals, 3) analysis of transi-
                            tion metals in non-aqueous media, 4) solid phase
                            extraction sample preparation techniques for extract-
                            able compounds, and 5) validated methods for fish
                            tissue and nutrients in marine systems.
                            Office or
                            Laboratory

                            OMMSQA/HQ

                            AREAL/RTP
                            EMSL/CIN
                            EMSL/LV
                 Contact
                 Total     Percent
              Funds($K) In-House
                                 597.1
Jack Puzak
Chris Saint
Robert Lee        345.0
William Budde     296.0
Llewellyn Williams 245.0
0

0
0
0
Modeling,
Monitoring Systems
and Quality
Assurance
Reducing Uncertainty in Ecological Risk
Assessment

    The goal of the program is to model the expected
response of representative estuaries in the region in
response to alternative risk management options as an
example of a systems level approach to ecological
risk assessment.
    In order to evaluate the uncertainty associated
with the temporal variability in indicators of ecosys-
tems condition, a field study is being undertaken in
the estuarine resources of a mid-Atlantic prototype
region. This activity is conducted in cooperation with
EPA's Environmental Monitoring and Assessment
Program (EMAP) and NOAA, and will target expo-
sure and condition indicators and their response to
changing pollutant levels. Ancillary data needed to
run and evaluate the transport and effects models that
will be applied to status and trends data is also being
collected as part of this effort. Analyses of the  data
from the first and second years of field research from
the prototype region will seek correlations  among
indicators that could identify possible causes of poor
condition and will  report the condition for  assessing
exposure and effects is  currently underway. Sensitivity
analyses are being performed and new multi-variate
techniques are being developed that will reduce
uncertainty in detecting regional changes and better
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                           evaluate effects models that can be used in ecological
                           risk assessment
                           Office or
                           Laboratory
                Contact
                           ERL/NARR     John Paul
                           OMMSQA/HQ  Chris Saint
  Total     Percent
Funds($K) In-House
                               2,750.0
              0
Modeling,
Monitoring Systems
and Quality
Assurance

and

Environmental
Processes and
Effects
Ecological Status and Trends

    The Environmental Monitoring and Assessment
Program (EMAP) is collecting, analyzing, and integrat-
ing environmental monitoring data from seven ecosys-
tem types found in the U.S.: Near-coastal
environments, forests, wetlands, surface waters,
agroecosystems, arid lands, and the Great Lakes.
    This information will allow EPA to better assess
the status and extent of current environmental prob-
lems, by providing associations between human-
induced stress and ecological condition. EMAP is also
establishing baseline conditions against which future
change can be measured, and assessing the degree to
which regulatory programs protect the nation's ecologi-
cal resources. EMAP is focusing on regional- and
national-scale problems and will target program
outputs at EPA officials who must respond to Con-
gress and the public, and senior managers who must
direct EPA's limited resources where they will be most
beneficial.
    Scientifically, EMAP will: (1) identify, character-
ize, classify, and quantify the ecological resources at
risk, (2) provide a probability-based statistical sam-
pling frame which provides unbiased estimates of
environmental conditions on a regional basis, (3)
identify, evaluate, and develop indicators of ecological
condition, (4) develop  operational monitoring programs
at a national level for resources of greatest concern,
and (5) develop data management and quality assur-
ance systems that allow timely analysis and periodic
reporting of program results.
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Office or
Laboratory
EMSL/CIN
ERL/COR
ERL/DUL
ERL/GB
EMSL/LV
ERL/NARR
OEPER/HQ
OMMSQA/HQ
AREAL/RTP
Total
Contact Funds($K)
Bob Graves 554.3
Hal Kibby 6130.2
Steve Hedtke 888.3
Kevin Sommers 3571.6
Bruce Jones 9,245.6
John Paul 1,068.2
Courtney Riordon 388.2
Rick Kutz 5,371.1
Jim Vickery 3,248.1
Percent
In-House
29.8
6.7
9.3
2.3
6.3
15.5
0
13.9
7.6
Exploratory
Research
Visiting Scientists Program

    The Visiting Scientists Program has two compo-
nents: The Resident Research Associateships Program
(RRAP) which is carried out in cooperation with the
National Research Council (NRC) and the Summer
Fellows Program (SFP) which is conducted in coopera-
tion with the American Association for the Advance-
ment of Science (AAAS). The objective of the RRAP
is to attract researchers into EPA's research laborato-
ries to assist in strengthening  the Agency's science
policy and program. Candidates are sought through
annual  advertisements in nationally known scientific
and engineering publications.  They are then subjected
to a rigorous peer review from which only the top
candidates are recommended for assignment to an EPA
laboratory.
    The Summer Fellows Program is carried out in
cooperation with the American Association for the
Advancement of Science and  sponsors the assignment
of mid-career environmental science and engineering
fellows to EPA facilities for the summer months to
conduct environmental research projects. In FY 1991,
10 highly qualified fellows were sponsored.
                           Office or
                           Laboratory

                           OER/HQ
                Contact

               Roger Cortesi
   Total     Percent
Funds ($K) In-House
     184.2
0
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Exploratory
Research
Small Business Innovation Research
(SBIR) Program

    Public Law 97-219 requires EPA to devote 1.25%
of its extramural research and development budget to
Small Business Innovation Research (SBIR). The SBIR
Program funds, via contracts, small businesses with
ideas relevant to EPA's mission. The program focuses
exclusively on projects in control technology or
process instrumentation development. Proposals are
solicited in the fall of each year for Phase I research.
Phase I research consists of feasibility studies which
are supported at a level of up to $50,000. Of these
Phase I studies, the best are selected for Phase II
studies where actual product development is  started.
Phase II studies are supported up to a level of
$150,000. To date, half of the Phase I efforts have
been supported in Phase II. Results from the SBIR
Program are expected to lead to the commercial
development of a product or process used in pollution
control.
                            Office or
                            Laboratory

                            OER/HQ
                 Contact

               Donald Carey
  Total     Percent
Funds($K) In-Housc
  2,500
0
Environmental
Processes and
Effects
Arctic Studies

    EPA's Arctic research program will focus research
on the nature, extent, and effects of exposure of Arctic
ecosystems on a regional scale to atmospheric contami-
nants. This effort will include analyses of the atmo-
spheric pathways for long-distance transport and
deposition, biogeochemical pathways at representative
depositional sites, and intermediate and ultimate sinks
for these contaminants. Effects research on  representa-
tive species of major ecosystems will be undertaken to
establish what risks there might be to species, includ-
ing humans. Landscape and regional ecosystem
sensitivity studies will follow the species risk studies.
These studies will culminate in an assessment of risk
in terms of character, magnitude, and timing of
changes, to Arctic biological systems from  atmospheri-
cally deposited contaminants. The program  will
implement a statistically balanced, spatial sampling
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                           design, based on the strategies of the EPA Environ-
                           mental Monitoring and Assessment Program (EMAP),
                           for the circumarctic region. The resultant data and
                           observational network will lead to conclusions about
                           the nature and extent of Arctic pollution, and subse-
                           quently will be used to develop, define parameters, and
                           test assessment models for mitigation and management
                           design strategies.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds ($K) In-House

                           ERL/COR     Dixon H. Landers   908.7      0
                           OEPER/HQ    Robert C. Worrest    51.7      0
                                          Paul Ringold
Modeling,
Monitoring Systems
and Quality
Assurance
Manage the Mandatory Quality Assurance
Program

    Each year, EPA devotes more than $500 million
to environmental data operations. Quality Assurance
(QA) activities play an integral role in the planning
and implementation of these operations, and in the
evaluation of the resulting data. By means of their QA
programs, EPA organizations can enjoy substantial
resource savings, because they collect only those data
that are needed, and because they can be sure that the
data they collect are appropriate for their intended use.
    Quality assurance is the process of management
review and oversight at the  planning, implementation,
and completion stages of an environmental data
collection activity to assure  that data provided by a
line operation to data users  are of the quality needed
and claimed. Quality assurance should not be confused
with quality control (QQ; QC includes those activities
required during data collection to produce the data
quality desired and to document the quality of the
collected data (e.g., sample  spikes and blanks).
    Quality assurance programs consist of specific
activities conducted before,  during and after environ-
mental data collection. During the planning of an
environmental data collection program,  QA activities
focus  on assuring that the quality of the data needed
by data users has been defined, and that a QC system
has been designed for measuring the quality of the
data being collected. During the implementation of a
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                            data collection effort, QA activities ensure that the QC
                            system is operating and that problems found by QC
                            are corrected. After environmental data are collected,
                            QA activities focus on assessing the quality of the data
                            obtained. Here, one determines whether the data
                            obtained are adequate to support data-dependent
                            regulatory decisions or research hypotheses.
                                The Quality Assurance Management Staff
                            (QAMS) is charged with overseeing the quality
                            assurance activities of the Agency. QAMS came into
                            being in May 1979, when the Agency recognized the
                            need for formalizing an Agency-wide quality assurance
                            program for all environmental data collection activities.
                            More recently, with the issuance of EPA Order 5360.1
                            in April 1984, the Agency's quality assurance program
                            has been significantly strengthened and broadened. The
                            Order mandates that QA be an integral part of all
                            environmental data collection activities, from planning
                            through implementation and review.
                                The Order identifies the activities basic to the
                            implementation of a QA program. These include:
                            •   requiring QA in all Agency-supported environmen-
                                tal data collection activities,
                            •   defining Data Quality Objectives,
                            •   developing quality assurance program and projects
                                plans,
                            •   conducting management and technical audits and
                                reviews,
                            •   implementing corrective actions based on the
                                audits,
                                establishing achievable data quality limits for
                                methods cited in EPA regulations,
                                developing and adopting technical guidelines for
                                assessing data quality, and
                                providing for QA training
                                In recent years, the Agency's QA activities have
                            focused on identifying the basic elements that are
                            essential to effective quality assurance for environmen-
                            tal data. QAMS has put considerable emphasis on
                            issuing guidance defining these key elements and
                            describing their importance in the efficient and
                            effective expenditure of resources assigned to environ-
                            mental data collection. This guidance development
                            phase has now been completed, and in  FY 1992
                            QAMS will continue with full-scale implementation
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                     Office or                 Total   Percent
                     Laboratory     Contact    Funds ($K) In-House

                     OMMSQA/HQ  Nancy Wentworth 1,681.3    51
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Radiation
Modeling,
Monitoring Systems
and Quality
Assurance
Off-Site Monitoring Program

    The off-site radiation safety program is designed
to monitor levels and trends of radioactivity in the
environment surrounding nuclear weapons testing areas
to verify testing conducted in compliance with existing
radiation protection standards. In the event of any
accidental release of radioactive contaminants, EMSL/
LV has the responsibility to take action to protect the
health and safety of the public. While the primary
monitoring efforts are conducted in the off-site areas
surrounding the Department of Energy's Nevada Test
Site, former test sites in  Alaska, Colorado, Mississippi,
and New Mexico are monitored on a routine basis.
    In addition, this program provides quality assur-
ance for the Agency's programs for monitoring
radiation in the environment. These are  supported by
providing a common source of radionuclide standards
and reference materials,  and through laboratory
intercomparison studies conducted to assure data of
known quality from analyses of environmental samples
such as milk, water, air and food.

Office or                       Total     Percent
Laboratory       Contact     Funds($K)  In-House
                           EMSIVLV      Charles Costa
                           OMMSQA/HQ  Dwight Hlustick
                                 178
100
Environmental
Engineering and
Technology
Demonstration
Scientific Support for Radon Program

    The goals of the radon mitigation research pro-
gram are to evaluate, develop, and demonstrate
innovative approaches to reduce indoor radon levels
and to understand the fundamental physical mecha-
nisms that influence indoor radon levels. The research
results are used to assist the Office of Radiation
Programs (ORP) implementation of the Agency's radon
program and to provide data on the latest radon
mitigation  approaches to regional and state officials
and the general public.
    Processes influencing radon entry are being
studied to provide the scientific basis for developing
new or improved (effective and economical) radon
reduction methods. ORD is using the data on radon
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                            and demonstrate techniques which will cost effectively
                            reduce indoor radon levels in new and existing homes,
                            schools and other structures to outdoor ambient air
                            levels (<1 pCi/L). This research supports the Agency's
                            mandate under the Indoor Radon Abatement Act
                            (IRAA) to reduce indoor radon levels to levels compa-
                            rable to those outdoors. Specific research includes:
                            bench and pilot scale testing to simulate the relative
                            importance of aggregate and surrounding soil on the
                            radon entry process; demonstrations to define the
                            ability of Active Soil Depressurization (ASD) systems
                            to consistently achieve levels < 1 pCi/L in homes,
                            shools, and other structures; determining the durability
                            and failure rate of currently applied mitigation systems;
                            evaluating innovative mitigation system designs;
                            demonstrating ASD and HVAC control systems as
                            radon mitigation options for schools; and understanding
                            the most significant factors that influence radon
                            mitigation costs. Technology transfer products includ-
                            ing updated technical manuals and brochures are being
                            produced for selected audiences.

                            Office or                        Total     Percent
                            Laboratory      Contact      Funds($K) In-House

                            AEERL/RTP    Michael Osborne  2,773      32
                            OEETD/HQ    Marshall Dick       200      78
Environmental
Engineering and
Technology
Demonstration
Electric and Magnetic Field Research
(EMF)

    The Electromagnetic Field (EMF) research
program is focusing on major issues identified in the
Agency's research strategy. Studies designed to verify
the suggested association between EMF exposure and
cancer are underway. The specific focus of these
studies is to determine a plausible biological mecha-
nism and conditions under which EMF promote or
induce cancer. In addition, efforts are being designed
to develop better exposure data and models to more
accurately determine actual human exposures.
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                      Office or                   Total    Percent
                      Laboratory     Contact    Funds($K) In-House

                      HERL/RTP    Joe Elder        935.1     7
                      OHR/HQ      Dave Kleffman
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Superfund
Modeling,
Monitoring Systems
and Quality
Assurance
Provide Techniques and Procedures for
Site and Situation Assessment

    Analytical protocols, sampling techniques, moni-
toring methods, and data interpretation approaches
useful for characterizing air, surface and ground water,
wastes, and soils at Superfund sites will be developed,
evaluated, and demonstrated. These methods include
air monitoring techniques, sample collection proce-
dures, geophysical methods; x-ray fluorescence
measurements of metal concentrations; remote sensing
techniques  and geographic information systems for
collection and analysis of present and historical site
data; soil core preparation procedures; portable gas
chromatography for volatile analysis; personal com-
puter-based geostatistics computer programs; and
hydraulic properties of soils.

Office or                     Total     Percent
Laboratory      Contact      Funds($K)  In-House

EMSL/CIN    William Budde      555.2    41
AREAL/RTP   William Mitchell    364.0    13
EMSL/LV      Michael Hiatt    1,608.2      8
OMMSQA/HQ Michael DeUarco     0        0
Environmental
Engineering and
Technology
Demonstration
Clean-up of Uncontrolled Hazardous
Waste Sites Requires Technologies for
Response and Remedial Action, for
Protecting the Personnel Involved and for
Supporting Enforcement Actions

    This research program develops and evaluates
clean-up technology, demonstrating prototype equip-
ment such as mobile thermal treatment and mobile soil
washing systems. Remedial technology will be as-
sessed and technical reports provided which will
include design data and cost information. Engineering
expertise will be applied to the assessment of uncon-
trolled hazardous waste site situations  to assist the
Office of Emergency and Remedial Response, Regions
and others in the development of corrective measure
options. In order to provide more effective long-term
technical support to the Regional Offices making
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                           cleanup decisions, the Superfund Technical Assistance
                           Response Team (START) program has been estab-
                           lished. In addition, short-term, quick turn-around
                           technical programs and consultation will be provided
                           to the regional programs and the Office of Waste
                           Programs Enforcement for enforcement support.
                               The Superfund Innovative Technology Evaluation
                           (SITE) program has been established to enhance the
                           development and demonstration, and thereby establish
                           the commercial availability,  of innovative  technologies
                           as alternatives to containment systems. The primary
                           goal of the SITE program is to evaluate these tech-
                           nologies on Superfund materials in order to develop
                           reliable cost and performance data.
                           Office or
                           Laboratory

                           RREL/CIN
                           OEETD/HQ
                 Contact

               R. Olexsey
               S. James
               B. Blaney
               R. Nalesnik
   Total     Percent
Funds ($K) In-House
  27,150
10
Modeling,
Monitoring Systems
and Quality
Assurance
Provide Quality Assurance—Superfund
Program Requirements

    Effective remedial actions at Superfund sites
depend upon analytical data of appropriate quality.
This program provides support to the Office of
Emergency and Remedial Response's Contract Labora-
tory Program (CLP), which is responsible for most
contract chemical analyses under the Superfund
program. Support is provided to the CLP in numerous
ways. Quality assurance reference materials, such  as
calibration standards, quality control samples, and
performance evaluation samples are prepared, and
distributed according to uniform and consistent
protocols for analysis by contract laboratories. The
analytical data generated by the laboratories are
audited in order to assess intra- and inter-laboratory
performance and method performance. These data are
maintained in the Quality Assurance/Quality Control
Data Base. On-site contract laboratory inspections are
performed to compliment the performance evaluations.
Based on method performance data, existing analytical
protocols are reviewed and improved. A quick re-
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Environmental
Processes and
Effects
                           sponse referee laboratory service is provided for use of
                           the EPA Regions.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds($K) In-House

                           EMSL/CTN     William Budde     962.8     17
                           EMSL/LV      Michael Hiatt    2,277.2     35
                           OMMSQA/HQ  Michael Dellarco
Provide Technical Support to Enforcement,
Program, and Regions

    This function provides rapid technical expertise
and services to the Office of Waste Programs Enforce-
ment, the Office of Emergency and Remedial Re-
sponse, Regional Offices, the Environmental Response
Team, Department of Justice, and state governments.
    Laboratory personnel and facilities are available on
a "when and where requested" basis to provide site-
and case-specific technical support. Assistance includes
training or advice on use of sampling and analytical
techniques and on use of appropriate assessment
models, including those for ecological risk estimation.
In addition, Technical Support Centers for information
on remedial action technologies, methods, case
histories, etc.,  will be continued. Bioassessment
assistance will focus on evaluation and application of
protocols to leachate and contaminated soil samples
and performing environmental assays. Technical
support will also be provided on contaminated marine
coastal areas and on polluted sediment remediation.

Office or         Total        Percent
Laboratory      Contact     Funds ($K) In-House

RSKERL/ADA  John Matthews    1,430.4     49.4
ERL/ATH       Rosemarie Russo   835.9     48.4
ERL/COR       Clarence Callahan  457.5     19.2
ERL/NARR     Norbert Jaworski   320.3     41.6
ERL/DUL       Nelson Thomas     47.7      0.0
ERL/GB        Raymond Wilhour  115.1     75.2
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Modeling,
Monitoring Systems
and Quality
Assurance
Provide Technical Support to Enforcement,
Program, and Regions

    Site specific monitoring and characterization for
all media in support of Superfund investigations is
provided to the Agency as part of the Technical
Support Program. Monitoring and characterization
support activities are provided on an as-requested
basis. These include: remote sensing for historical and
current site assessment; air, water, ground-water, and
soils monitoring for site characterization; and analytical
chemistry support. Advice and technical assistance on
sampling methods, design of sampling plans, and
sample analysis is provided. The full range of quality
assurance/quality control assistance is offered including
design and review of quality assurance plans, provision
of quality control materials, and data analysis and
interpretation.

Office or                      Total     Percent
Laboratory      Contact     Funds($K) In-House

EMSL/CIN      William Budde     406.9    33
AREAL/RTP    William Mitchell    560.6    39
EMSL/LV      Michael Hiatt     1553.8    44
OMMSQA/HQ  Michael Dellarco
Scientific
Assessment
Provide Technical Support to Enforcement,
Program, and Regional Offices

    Risk assessment support is being provided to
support enforcement, program, and regional office
needs for both the remedial planning and cost recovery
efforts. Major efforts include review assessments
submitted by regions; provision of risk assessment
information, often on a quick turnaround, through a
Technical Support Center for Health and Risk Assess-
ment; development of guidance materials; and offering
training courses.
                          Office or
                          Laboratory

                          OHEA/HQ
                          ECAO/CIN
                Contact

               Kevin Garrahan
               Pei-Feng Hurst
   Total     Percent
Funds ($K) In-House
    997
71.3
                                 96

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Superfund
Health Effects
Hazardous Substances Health Effects/Risk
Assessment and Detection Research

    Research develops data and methods to improve
the Superfund human health evaluation process,
evaluate the health effects associated with cleanup
options, and develops biomonitoring methods. The
Superfund risk assessment process involves assessment
of toxicity, exposure, and dose in support of the
characterization of risk. The research provides im-
proved health evaluation measures to detect, assess,
and evaluate the risks to human health from hazardous
substances as needed for Superfund removal and
remedial cleanup decisions.
    Research will be implemented to evaluate the
additivity assumption now being used in the assess-
ment of waste mixtures. Test methods  will develop
screening techniques for early detection of adverse
health effects, and  improved measurement of health
endpoints particularly noncancer endpoints such as
reproductive effects. Predictive techniques that can
reduce the uncertainties in risk assessment caused by
data limitations will be developed and  site-specific data
will be generated in response to requests from the
Office of Emergency and Remedial Response, the
Office of Waste Programs Enforcement and EPA
Regional Offices.
                           Office or
                           Laboratory

                           HERL/RTP
                           OHR/HQ
                 Contact

               Robert Dyer
               Thomas Miller
   Total     Percent
Funds ($K) In-House
   3,462
12
Scientific
Assessment
Hazardous Substances Health Effects/Risk
Assessment and Detection Research

    The scientific assessment research program is
developing data and procedures for filling in knowl-
edge and information gaps that exist in the Superfund
public health evaluation process. Specific areas of
research include improved evaluation techniques for
non-cancer health effects, research programs in
pharmacokinetic modeling, understanding of
biomarkers, understanding of complex mixtures, and
                                  97

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Superfund
                          development of improved exposure assessment meth-
                          odology, especially as it relates to complex exposures.
                          Office or
                          Laboratory

                          OHEA/HQ
                Contact

              Michael Callahan  1,972
   Total     Percent
Funds ($K) In-House
              8.6
Scientific
Assessment
Health Effects Assessments

    Health and environmental effects documents are
being prepared for the chemicals most frequently found
at candidate sites to assist OERR, the Enforcement
office and the Regions in evaluating alternative
cleanup decisions at uncontrolled waste sites.
                          Office or
                          Laboratory

                          ECAO/CIN
                Contact

              Bruce Peirano
   Total     Percent
Funds ($K) In-House
    540
55.0
Scientific
Assessment
Superfund Reporteble Quantity Regulatory
Efforts

    Chemical-specific data are being provided on
carcinogenicity and chronic effects to support estab-
lishment or adjustment of Reportable Quantities (RQs)
for CERCLA Hazardous Substances. These include
chemical-specific information for listing of hazardous
wastes as CERCLA Hazardous Substances in associa-
tion with Section 3001 of RCRA, consideration of
other lists of chemicals to be CERCLA Hazardous
Substances, designations of new substances, and
updates to previous RQ calculations.
                          Office or
                          Laboratory

                          OHEA/HQ
                Contact

               Bruce Peirano
   Total     Percent
Funds ($K) In-House
     728
24.5
                                 98

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Superlund
Environmental
Processes and
Effects
Field Screening Techniques for
Assessment and Evaluation

    This research activity is designed to develop
procedures for evaluating the ecological hazards and
risks associated with hazardous waste sites and their
remedial operations. Ecological endpoints, important to
the Superfund program, will be identified and appro-
priate methods for evaluating the ecological hazards
and risks associated with hazardous wastes at Super-
fund sites will be validated. Available methods will be
customized to the extent possible to provide site-
specific field assessment methods. A multimedia,
human exposure/risk assessment methodology for
prioritizing candidate remedial action sites in terms of
their threats to human health will be developed and
applied.
    A second purpose is to acquire subsurface process
and characterization information that will allow
development of a decision-making framework for
evaluating the appropriateness and potential efficacy of
remediation technologies such as pump-and-treat and
various physical/chemical/biological methods. The
program will consist of studies on methods for site
characterization, immiscible fluid flow and residual
saturation, mass transport in heterogenous media, and
accelerated remediation  methods.

Office or                      Total     Percent
Laboratory      Contact     Funds ($K) In-House

RSKERL/ADA  James  McNabb    832.6     0
ERL/ATH       Rosemarie Russo    80.3    53.5
ERL/NARR     William G. Nelson  297.4     0
ERL/COR       Anne Fairbrother    200.0     0
ERL/DUL       Philip M. Cook    115.5    33.8
Modeling,
Monitoring Systems
and Quality
Assurance
Field Screening Techniques for
Assessment and Evaluation

    Section 31 lc of the Superfund Amendments and
Reauthorization Act authorizes EPA to conduct
research "with respect to ... detection of hazardous
substances in the environment." The purpose of this
                                 99

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Superfund
                           program is to develop and evaluate monitoring tech-
                           niques and systems which are rapid and inexpensive,
                           fill technical voids, integrate monitoring systems into
                           multimedia site assessments, and are as specific,
                           selective and sensitive as possible. Innovative ap-
                           proaches which offer potentially significant cost and
                           time savings to Superfund site investigations are
                           studied. These include: development of improved
                           statistical sampling designs, development of improved
                           techniques for managing and interpreting field data,
                           and development of screening techniques such as
                           immunoassay and chemical  sensors.

                           Office or                       Total     Percent
                           Laboratory      Contact     Funds($K)  In-House

                           EMSL/LV       Michael Hiatt    1,871.5    11
                           OMMSQA/HQ  Michael Dellarco
Modeling,
Monitoring Systems
and Quality
Assurance
Monitoring Technology, Development, and
Demonstration

    Section 31 Ib of the Superfund Amendments and
Reauthorization Act requires EPA to conduct the
Superfund Innovative Technology Evaluation (SITE)
program, which seeks to accelerate the application of
promising new technologies to Superfund problems.
Examples of technologies being studied and demon-
strated include fiber optic chemical sensors for ground
water contamination, immunoassay systems for organic
contamination, canisters for air sampling, x-ray
fluorescence for rapid metals screening, geophysical
equipment for remote sensing of buried waste, and
cone penetrometers for rapid and extended depth soil
sampling.

Office or                       Total    Percent
Laboratory      Contact      Funds($K) In-House
                           EMSL/LV      Michael Hiatt
                           OMMSQA/HQ  Michael Dellarco
                                689.4
16
                                  100

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Superfund
Exploratory
Research
Hazardous Substance Research Centers
Program

    Authorized by the 1986 amendments to the
Superfund Act, the Hazardous Substance Research
Centers (HSRC) program supports five university-
based research centers across the country.
    The centers, which consist of multi-university
consortia, were selected through a competitive peer
review process and established in February 1989. Each
center has an eight-year life expectancy and receives
$1.0 million annually from EPA/OER. At least 20% of
the total center's resources must be provided by
university, state, or private sources. In addition, each
center is building additional federal and industrial
support for their research and technology transfer
programs. This additional support is helping build the
reputation of the centers as experts in research  and
technology transfer for hazardous substance manage-
ment The lead institution and research focus of each
center include:

Region-Pair 1-2: New Jersey Institute of Technology:
    Incineration
Region-Pair 3-5: The University of Michigan: Biore-
    mediation
Region-Pair 4-6: North Carolina State University:
    Waste minimization
Region-Pair 7-8: Kansas State University: Soils
Region-Pair 9-10: Stanford University: Groundwater
                           Office or
                           Laboratory

                           OER/HQ
                 Contact

               Dale Manty
   Total     Percent
Funds ($K) In-House

   5,000        0
Exploratory
Research
Small Business Innovation Research
(SBIR) Program—Superfund

    EPA is required to devote 1.25% of its extramural
budget to Small Business Innovation Research (SBIR).
The SBIR Program funds, via contracts, small busi-
nesses with ideas relevant to EPA's mission. Proposals
are solicited in the fall of each year for Phase I
research. Phase I research consists of feasibility studies
       101

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Superfund
                           which are supported at a level of up to $50,000. Of
                           these Phase I studies, the best are selected for Phase II
                           studies where actual product development is started.
                           Phase II studies are supported up to a level of
                           $150,000. Results from the SBIR Program are ex-
                           pected to lead to the commercial development of a
                           product or process used in pollution control.
                           Office or
                           Laboratory

                           OER/HQ
                 Contact

               Donald Carey
   Total     Percent
Funds ($K) In-House
    692
  0
Exploratory
Research
Superfund Research Grants

    The Superfund research grants program supports
research initiated by individual investigators in areas of
priority interest to the Agency. Research proposals are
solicited via the Request for Applications (RFA),
which is a targeted solicitation mechanism that
identifies Agency research needs in well-defined areas.
Only proposals which specifically address those needs
are accepted for review and possible funding.
                           Office or
                           Laboratory

                           OER/HQ
                 Contact

               Roger Cortesi
   Total     Percent
Funds ($K) In-House
   1,649.1
0
Environmental
Processes and
Effects
Evaluate Technologies to Manage
Uncontrolled Waste Sites

    This research activity is focused on evaluating
both naturally-occurring and improved microorganisms
for the degradation of hazardous substances. Present
knowledge and available biodegradation technology
will be expanded to enable this cleanup technique to
be advanced as a viable option to existing chemical
and physical remediation processes.
    To effect cleanup of hazardous chemicals in the
environment, edaphic and genetic methods to enhance
the biodegradative ability of indigenous and introduced
microorganisms are  being studied. Principles for
application of this information to hazardous waste sites
                                  102

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Superfund
                          are being developed using in-situ and above-ground
                          reactor technology. The program will identify high
                          priority chemical structures for study, develop gene
                          banks of novel capabilities, and develop approaches for
                          rapid biodegradation. All extramural monies will be
                          expended by the participating laboratories subject to
                          final planning actions.

                          Office or                       Total     Percent
                          Laboratory      Contact     Funds ($K) In-House

                          RSKERL/ADA John T. Wilson    642.2     27.9
                          ERL/ATH      Rosemarie Russo   586.4     14.7
                          ERL/GB       HapPritchard      845.3     10.3
                                 103

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Overview
 Introduction

     The primary goal of the U.S. Environmental Protection Agency is to mitigate the
 adverse impacts of pollution on human health and the environment. Toward that end,
 Agency management must make decisions regarding the development of policy,
 guidance, standards, regulations, and the appropriate tools for implementing pollution
 abatement strategies. It is the primary  mission of the Office of Research and Devel-
 opment (ORD) to  provide high quality, timely scientific and technical information in
 the service of Agency goals. The Agency's research program is conducted through 12
 environmental laboratories across the country, employing some 1900 people, with an
 annual budget of about $490 million. The research focuses on areas targeted by the
 planning process as needing additional emphasis in order to provide the information
 required for Agency decision making.

 Research Perspectives

     The overall planning process engenders an applied research and development
 program focused on answering key scientific and technical questions related  to EPA's
 decision making, short-term scientific  and technical studies supporting immediate
 regulatory and enforcement decisions.  In addition, ORD maintains  a longer-term core
 research program that extends the knowledge base of environmental science and
 anticipates environmental problems. This research  and development program is
 focused on the following functional areas:

 •    Health effects research—to determine exposure and adverse effects of pollutants
     on human health

 •    Ecological effects research—to determine exposure and adverse effects of
     pollutants on ecological resources

 •    Environmental process and fate research—to understand how pollutants are
     transported  and modified as they move through soils, ground and surface waters,
     and  the atmosphere

 •    Environmental monitoring research—to develop methods of identifying pollutants
     in the environment and measuring exposure to such substances and to develop
     indicators by which  the status and trends of ecosystems can be identified

 •    Risk assessment research—to develop methods to integrate information on
     pollutant sources, fate and transport, exposure, and health and  ecological effects
     in order to assess the overall risk  posed  by a pollutant or a group of pollutants

     Risk reduction research—to develop methods  and technologies to reduce or
     eliminate the sources of pollutants or to  prevent exposure to pollutants; to
     develop  control  technologies to treat, destroy, or contain pollutants

         In addition to functional areas, several cross-media problems also categorize
 the total ORD program. Those cross-media problems receiving special emphasis at
 present and for the foreseeable future  and the Agency programs most concerned are:

                                    104

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Overview
•   Global climate change (air, water, hazardous waste);

•   Environmental Monitoring and Assessment (water, air, energy);

•   Total and human exposure assessment (air, water, hazardous waste/Superfund,
    pesticides/toxic substances);

•   Ground Water (water, hazardous waste/Superfund);

•   Pollution Prevention (hazardous waste, pesticides, multimedia);

•   Comparative risk for complex mixtures (air, water, hazardous waste/Superfund,
    pesticides/toxic substances); and

    Technology Transfer (all).

Conclusions

    ORD's ongoing activities evolve from a process of mediation between research
concepts and regulatory/programmatic applications, as well as from a growing fund of
commonly held priorities and core values. Increasingly, ORD plans new expanded
research based on issues that pose the greatest risk to human health and the environ-
ment As the Agency continues to refine strategies for addressing increasingly com-
plex environmental problems, the goal of ORD is to affect those strategies with sound
science, sound judgment, and vision.
                                   105

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    Office of Research
   Program Management
   Clarence Marian, Dir.
                                                 Assistant Administrator for
                                                 Research and Development
                                                      Erich Bretthauer
                    Deputy Assistant Administrator
                            John Skinner
   Office of Modeling,
  Monitoring Systems &
   Quality Assurance
  H. Matthew Bills,* Dir
       Atmospheric
        Research &
         Exposure
       Assessment
      Lab., Reserach
     Triangle Park, NC
      Gary Foley, Dir.
       Environmental
     Monitoring Systems
     Lab., Cincinnati, OH
       Tom Clark, Dir.,
Office of Environmenta!
    Engineering &
     Technology
    Demonstration
  Alfred Lindsey, Dir.
   Risk Reduction
  Engineering Lab.,
   Cincinnati, OH
 Timothy Oppelt, Dir.
     Air & Energy
     Engineering
    Research Lab.,
   Research Triangle
       Park, NC
  Frank Princiotta, Dir.
       Environmental
     Monitoring Systems
     Lab., Las Vegas, NV
    Robert Snelling, * Dir.
•Acting
Office of Environmental
  Processes & Effects
      Research
Courtney Riordan, Dir.
  Environmental Research
    Lab., Corvallis, OR
   Thomas Murphy, Dir.
                           Environmental Research
                              Lab., Athens, GA
                            Rosemane Russo, Dir.
  Environmental Research
     Lab., Duluth, MN
     Oilman Veith, Dir. ,
                          Environmental Research
                           Lab., Narragansett, Rl
                           Norbert Jaworski, Dir.
                                                      Environmental Research
                                                       Lab., Gulf Breeze, FL
                                                        Robert Menzer, Dir.
                                                      R.S. Kerr Environmental
                                                      Research Lab., Ada, OK
                                                         Clinton  Hall,  Dir.
Research
Roger Cortesi, Dir.
Support
Peter Preuss, Dir.


Office of Health
Research
Ken Sexton, Dir.

Health Effects
Research Lab.,
Research Triangle
Park, NC
Lawrence Reiter,
Dir



Center for
Environmental
Research Information,
Cincinnati OH
Calivn Lawrence, Dir.

Office of Health &
Environmental
Assessment
William Fariand, Dir.




Human Health
Assessment Group
Hugh McKinnon, Dir.
Exposure Assessment
Group
Michael Callahan, Dir.
Environmental Criteria
& Assessment Office,
Research Triangle
Park, NC
Lester Grant, Dir.
Environmental Criteria
& Assessment Office
Cincinnati, OH
Terence Harvey, Dir.



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ORD Organization
    Please note, the list below includes both commercial (CML) and Federal (FTS)
telephone numbers. Where only one number is listed, it serves both purposes.

    Assistant Administrator for Research and Development-

     Erich Bretthauer                                        (202) 260-7676
     Headquarters, Washington, DC (RD-672)

    Deputy Assistant Administrator

     John H. Skinner                                        (202) 260-7676
     Headquarters, Washington, DC (RD-672)

    Senior ORD Official, Cincinnati

     Senior Official,  Calvin O. Lawrence                   CML (513) 569-7951
     Cincinnati, OH 45268                                   FTS 8-684-7951

    Office of Senior ORD Official, Cincinnati

     Director, Andrew Avel                              CML (513) 569-7951
     Cincinnati, OH 45268                                   FTS 8-684-7951

    Senior ORD Official, Research Triangle Park

     Senior Official, Gary Foley                           CML (919) 541-2613
     Research Triangle Park, NC 27711                        FTS 8-629-2613

    Office of Senior ORD Official, Research Triangle Park

     Director, John J. Neal                               CML (919) 541-0179
     Research Triangle Park, NC 27711                        FTS 8-629-0179
   Office of Technology Transfer and Regulatory Support

     Director, Peter W. Preuss                                 (202) 260-7669
     Headquarters, Washington, DC (H-8105)
     Deputy Director, Jay Benforado                            (202) 260-7669

     Regulatory Support  Staff
     Director, Jay Benforado                                   (202) 260-7669

     Technology Transfer Staff
       Director, Mike Moore                                  (202) 260-7671

     Center for Environmental  Research Information (CERI)
       Director,  Calvin Lawrence                          CML (513) 569-7391
       Cincinnati, OH 45268                                 FTS 8-684-7391

                                 107

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ORD Organization
     Regional Operations Staff
       Director, David Klauder                                (202) 260-7667
         Regional Scientist Program Coordinator,
            Ron Landy                                      (202) 260-7667
         Superfund Technical Liaison Program Coordinator
            Jerry R. Carman                                  (202) 260-7667
    Office of Research Program Management

     Director, Clarence E. Mahan
     Deputy Director, (Vacant)
     Headquarters, Washington, DC (RD-674)

     Evaluation and Review Staff
       Chief, Thomas L. Hadd

     Planning Staff
       Chief, Peter Durant

     Program and Information Management Staff
       Chief, Linda K. Smith

     Program Coordination Staff
       Chief, Joanne Rodman

    Information System Staff
       Chief, Clifford Moore
     (202) 260-7500
CML (202) 260-7659
    FTS 8-260-7659

CML'(202) 260-2597
    FTS 8-260-2597

CML (202) 260-7462
    FTS 8-260-7462

CML (202) 260-7468
    FTS 8-260-7468

CML (202) 260-7471
    FTS 8-260-7471
    Office of Environmental Engineering and Technology
    Demonstration

     Director, Alfred Lindsey                                  (202) 260-2600
     Deputy Director, Stephen Lingle
     Headquarters, Washington, DC (RD-681)

     Program Development Staff
        Director, Greg Ondich                                 (202) 260-5748

     Program Management Staff
        Director, Al Galli                                     (202) 260-2583
        Deputy Director, Steve Jackson
                                  108

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ORD Organization
     Field Laboratories

       Air and Energy Engineering Research Laboratory
          Director, Frank Princiotta (MD-60)                CML (919) 541-2821
          Deputy Director, Blair Martin                        FTS 8-629-2821
          Research Triangle Park, NC 27711
       Risk Reduction Engineering Laboratory
          Director, E. Timothy Oppelt                      CML (513) 569-7418
          Deputy Director, John Convery                       FTS 8-684-7418
          Cincinnati, OH 45268

     Releases Control Branch
          Chief, Jack Farlow                             CML (201) 321-6635
          Edison, NJ  08817                                  FTS 8-340-6635
    Office of Environmental Processes and Effects Research

     Director, Courtney Riordan                                (202) 260-5950
     Deputy Director, Michael W. Slimak
     Headquarters, Washington, DC (RD-682)

     Program Operations Staff
       Director, Patricia M. Neuschatz                          (202) 260-5962

     Terrestrial and Ground Water Effects Staff
       Director, Jackie Durham                                (202) 260-8930

     Marine, Freshwater and Modeling Staff
       Director, (Vacant)                                     (202) 260-5791

     Field Laboratories

       Robert S. Kerr Environmental Research Laboratory
          Director, Clinton W. Hall                        CML (405) 332-8800
          P.O. Box 1198                                    FTS 8-743-2224
          Ada, OK 74820

       Environmental Research Laboratory
          Director, Rosemarie C. Russo                    CML (404) 546-3500
          Director for Research Operations,                     FTS 8-250-3500
            Robert R. Swank
          College Station Road
          Athens, GA 30613
                                 109

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ORD Organization
       Environmental Research Laboratory
         Director, Thomas A. Murphy                    CML (503) 757-4601
         Deputy Director, Robert T. Lackey                   FTS 8-420-4601
         200 SW 35th Street
         Corvallis, OR 97333

       Environmental Research Laboratory
         Director, Oilman D. Veith                      CML (218) 727-6692
         Associate Director for Research,                     FTS 8-780-5550
            Steven F. Hedtke
         6201 Congdon Boulevard
         Duluth, MN 55804

         Monticello Field Station                                 CML only
         Box 500                                          (612) 295-5145
         Monticello, MN 55362

         Large Lakes Research Station                   CML (313) 692-7600
         9311 Groh Road                                  FTS 8-378-7600
         Grosse He, MI 48138

       Environmental Research Laboratory
         .Director, Norbert A. Jaworski                   CML (401) 782-3001
         Acting Deputy Director, Donald K. Phelps             FTS 8-838-6001
         South Ferry Road
         Nairagansett, RI 02882

         Hatfield Marine Science Center                  CML (503) 867-4040
         Newport, OR 97365                               FTS 8-430-4040

       Environmental Research Laboratory
         Director, Robert E. Menzer                     CML (904) 934-9200
         Deputy Director, Raymond G. Wilhour                FTS 8-228-9200
         Sabine Island
         Gulf Breeze, FL 32561
    Office of Exploratory Research

     Director, Roger Cortesi                                  (202) 260-5750
     Headquarters, Washington, DC (RD-675)

     Research Grants Staff
       Director, Robert Papetti                               (202) 260-7473

     Research Centers Program
       Director, Karen Morehouse                            (202) 260-5750

                                 110

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ORD Organization
     Visiting Scientists Program
       Coordinator, Alvin Edwards

     Small Business Innovation Research Program
       Director, Donald Carey
      (202) 260-7473


      (202) 383-7445
    Office of Health and Environmental Assessment

     Director, William H. Farland
     Headquarters, Washington, DC (RD-689)

     Program Operations Staff
       Director, Barry Goldfarb
     Program Liaison Staff
       Director, Jerry Moore

     Technical Information Staff
       Director, Marie Pfaff

     Human Health Assessment Group
       Director, Hugh McKinnon

     Exposure Assessment Group
       Director, Michael Callahan

     Environmental Criteria and Assessment Office
       Director, Lester Grant (MD-52)
       Research Triangle Park, NC 27711

     Environmental Criteria and Assessment Office
       Director, Terence Harvey
       Cincinnati, OH 45268
CML (202) 260-7315
     FTS 8-260-7315

CML (202) 260-7311
     FTS 8-260-7311
CML (202) 260-7323
     FTS 8-260-7323

CML (202) 260-7345
     FTS 8-260-7345

CML (202) 260-7338
     FTS 8-260-7338

CML (202) 260-8909
     FTS 8-260-8909
CML (919) 541-4173
     FTS 8-629-4173
CML (513) 569-7531
    FTS 8-684-7531
   Office of Health Research

    Director, Ken Sexton
    Deputy Director, David Kleffman
    Headquarters, Washington, DC (RD-683)

    Health Research Management Staff
       Director, Mary Ellen Radzikowski

    Health Effects Research Laboratory
       Director, Lawrence W. Reiter (MD-51)
       Deputy Director, Harold Zenick
     (202) 260-5900
     (202) 260-5891
CML (919) 541-2281
    FTS 8-629-2281
                                 111

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ORD Organization
    Office of Modeling, Monitoring Systems and Quality Assurance

     Acting Director, H. Matthew Bills                         (202) 260-5767
     Acting Deputy Director, Jack Puzak
     Associate Director, Jack Puzak                            (202) 260-5767
     Headquarters, Washington, DC (RD-680)

     Program Operations Staff
       Director, Paul D. Palm                                (202) 260-5761

     Quality Assurance Management Staff
       Director, Nancy Wentworth                             (202) 260-5763

     Modeling and Monitoring Systems Staff
        Director, Fredrick W. Kutz                            (202) 260-5776

    Environmental Monitoring and Assessment Program (EMAP) Staff
       Acting Director, Fredrick W. Kutz                      (202) 260-5776

     Atmospheric Research and Exposure
     Assessment Laboratory
       Director, Gary J. Foley                           CML (919) 541-2106
       Deputy Director, (Vacant)                             FTS 8-629-2106
       Research  Triangle Park, NC 27711

     Environmental Monitoring Systems Laboratory
       Director, Thomas A. Clark                        CML (513) 569-7301
       Deputy Director, Gerald D.  McKee                      FTS 8-684-7301
       Cincinnati, OH 45268

     Environmental Monitoring Systems Laboratory
       Acting Director, Robert N. Snelling                 CML (702) 798-2525
       Acting Deputy Director, Margaret A. Rostker             FTS 8-545-2525
       P.O. Box 93478
       Las Vegas, NV 89193-3478

     Vint Hill Station
       Director,  Donald Garofalo                         CML (703) 347-6224
       P.O. Box 1587, Building 166                           FTS 8-557-3110
       Warrenton, VA 22186
                                 112

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ORD Organizational  Descriptions
Office of
Technology
Transfer and
Regulatory Support
    The Office of Technology Transfer and Regulatory
Support (OTTOS) is responsible for three broad
functions. The first function is to ensure that the
Agency's regulations, legislation, and other policy
decisions are based on the best scientific and technical
information available. OTTRS staff coordinates the
input from ORD offices and laboratories to the
regulations and participates at all levels of the regula-
tory process. The second function, technology transfer,
implements a program to share the results of ORD's
research and development outside the Agency. In
coordination with the laboratories and program offices,
OTTOS and the Center for Environmental Research
Information (CERI) develop technology transfer
products. Those products include databases, publica-
tions, seminars, and workshops which are available to
state and local governments, academia, international
organizations, as well as others with an interest in
environmental science and technology.  The third
function, regional operations, is the ORD liaison with
EPA's regional offices. Regional operations staff
promotes regional interests  in the research planning
process as well as technology transfer through the
Regional Scientist Program and the Regional Super-
fund Technical  Liaison Program.
Office of Research
Program
Management
    The Office of Research Program Management
(ORPM) is a principal staff office to the Assistant
Administrator. In this role, ORPM provides executive
leadership and guidance on matters of budgeting,
accountability, program planning, analysis, review,
integration and coordination, resource management,
organizational and manpower management, environ-
mental compliance, policy development and analysis,
and administrative development and management
services. ORPM is responsible  for the overall budget
execution and financial management of all ORD
resources. ORPM is also responsible for assuring that
the budget requests to the Agency, OMB, and Con-
gress respond to the regulatory and programmatic
needs of EPA, while at the same time anticipating
future environmental research necessary to address
emerging issues. ORPM also has national responsibil-
ity for human resource management (HRM) programs
within ORD, with the ORD Comprehensive Human
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ORD Organizational Descriptions
                           Resource Management Plan providing the basis for
                           these programs.
Office of
Environmental
Engineering and
Technology
Demonstration
    The Office of Environmental Engineering and
Technology Demonstration (OEETD) is responsible for
the assessment and the development of methods for
control of the environmental and socio-economic
impacts of municipal and industrial operations and of
energy and mineral resource extraction, processing,
conversion, and utilization systems.
    The Risk Reduction Engineering Laboratory in
Cincinnati, Ohio, investigates ways to prevent, control,
and treat hazardous wastes and Superfund related
activities. This includes defining and characterizing
sources of pollution, catalyzing advances in the  state-
of-the-art of pollution control, providing engineering
concepts for cost-effective engineering solutions to
difficult pollution problems and early-warning of
emerging sources of pollution.
    It also investigates, develops and demonstrates
cost-effective methods for the treatment and manage-
ment of municipal wastewater and sludges and urban
runoff; and of industrial processing and  manufacturing
and toxic discharges; and the development of technol-
ogy and management systems for the treatment,
distribution and presentation of public drinking water
supplies.

    Drinking Water: This research program integrates
    chemistry, engineering, microbiology, and cost to
    provide effective, reliable, and cost-effective
    techniques for assuring the delivery of safe
    drinking water to reduce the risk of chemically
    and microbiologically induced health effects to the
    public. Included are laboratory, pilot plant, and
    field studies on control of lead,  radon, synthetic
    organics, disinfection by-products, viruses, and
    cysts.

•   Hazardous Wastes: This program focuses on
    investigating incineration, land disposal and
    alternative technologies for  treating, detoxifying,
    and disposing of hazardous  wastes.

•   LUST Trust Fund Technical Support: This pro-
    gram works in close support to the Office of
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ORD Organizational  Descriptions
                               Underground Storage Tanks (OUST) to develop
                               procedures for detecting and preventing leaks from
                               storage tanks and associated piping. Under the
                               LUST Trust Fund, technical assistance is provided
                               on site assessment, technology selection, and
                               corrective action to decision officials.

                               Pesticides: This research program evaluates
                               processes for treating wastes from production,
                               application and disposal of pesticides. The pro-
                               gram also evaluates treatment alternatives  for
                               disposing cancelled and suspended pesticides, and
                               provides data and guidance on the effectiveness of
                               protective equipment for reducing worker  exposure
                               to pesticides.

                               Superfund: Research is  directed at identifying,
                               developing and evaluating technologies to support
                               remediation, removal and enforcement actions. The
                               Superfund Innovative Technology Evaluation
                               (SITE) program facilitates development and
                               conducts demonstrations of innovative technolo-
                               gies as alternatives to containment. The Superfund
                               Technical Assistance Response Team (START)
                               provides engineering and scientific assistance to
                               Regional Offices, Program Offices, and others on
                               the cleanup of hazardous wastes, particularly those
                               associated with Superfund sites.

                               Toxic Chemical Testing  and Assessment: One goal
                               of this research program is to provide test proto-
                               cols, treatment and control procedures for  regulat-
                               ing the manufacture and use of existing toxic
                               chemicals (including asbestos); assessing release
                               and exposure in review  of Premanufacturing
                               Notices (PMNs) for new chemicals; and evaluating
                               techniques and devices to contain and destroy
                               genetically engineered organisms are two other
                               goals.

                               Wastewater Treatment (Municipal and Industrial):
                               Research efforts are focused on developing cost-
                               effective methods for treating municipal wastewa-
                               ter and sludges, urban runoff, and industrial
                               wastewater discharges from processing and
                               manufacturing operations. The main goal is to
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ORD Organizational  Descriptions
                               provide design and operating guidelines for
                               efficient wastewater management based on the
                               principles of pollution prevention and process
                               integration. The research also includes the devel-
                               opment of toxicity-based permitting via use of
                               bioassay procedures.

                           •   Municipal Waste: This program promotes the
                               integration of municipal solid waste management
                               technologies through research on safe and effective
                               recycling practices, reducing multimedia pollutant
                               releases from municipal land disposal facilities,
                               and research on the utilization and safe disposal of
                               municipal waste combustion residues.

                           •   Pollution Prevention: Research is conducted (1) to
                               assess opportunities for multi-media pollution
                               prevention through source reduction and recycling
                               within operating industrial facilities, (2) to develop
                               and demonstrate innovative pollution prevention
                               technologies for industrial and transportation sector
                               processes, (3) to develop and standardize method-
                               ologies for performing consumer product life cycle
                               analyses and for measuring waste reduction.

                           •   Oilspills: As a result of EPA's involvement in
                               efforts to clean up the Alaskan oil spill, research
                               is underway to develop and evaluate remediation
                               technologies. The program  emphasizes exploiting
                               the natural ability of indigenous microorganisms to
                               degrade oil, with or without nutrient addition.

                               The major purpose of  the Air and Energy Engi-
                           neering Research Laboratory  is to develop  and assess
                           methods and technologies for preventing, or reducing
                           the effects of air pollutants on human  health and
                           welfare, and on the global  environment.

                           •   Acid Rain: This program focuses on developing
                               innovative controls for acid rain precursors, SO2
                               and NOx, including the Limestone Injection
                               Multistage Burner; developing models that will
                               identify the best possible control alternatives for
                               various scenarios; and developing inventories of
                               acid rain precursor emissions.
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                               Air Toxics: Emphasis is placed on developing
                               technologies and pollution prevention approaches
                               to reduce emissions of volatile organic compounds
                               (VOCs); identifying sources of VOCs; developing
                               improved designs that will achieve better control
                               of woodstove emissions; and providing direct
                               technical assistance to state and local agencies
                               through the Control Technology Center (CTC)
                               which has extensive information on existing
                               technologies applicable to a variety of air pollution
                               sources.

                               Hazardous Wastes: The primary goal of this
                               program is to study the fundamental combustion
                               mechanisms that influence thermal destruction of
                               hazardous wastes. Included are studies of metal
                               aerosols from waste incineration, failure modes in
                               a small pilot-scale rotary kiln, and small pilot-
                               scale studies of fluidized-bed incineration.

                               Indoor Air Quality/Radon: Research is currently
                               concentrating on (1) developing and demonstrating
                               technologies for reducing the entry of naturally-
                               occurring radon into houses, schools and other
                               public buildings, (2) studying emissions from
                               building materials and consumer products as
                               sources of indoor air pollution, (3) evaluating the
                               effects of "sinks" that adsorb/desorb pollutants in
                               the indoor environment, and (4) evaluating indoor
                               air control options for gases and particles.

                               Municipal Waste Combustion: Work focuses on
                               evaluating techniques to minimize pollutant
                               formation during combustion, and determining the
                               effectiveness of various devices in controlling air
                               pollution  from municipal waste incinerators.

                               Ozone Non-Attainment: This program supports
                               ORD's overall ozone non-attainment strategy by
                               developing innovative technologies, mitigation
                               strategies, process modifications and improving
                               existing technologies which  will prevent, or
                               reduce, the emission of hydrocarbons, nitrogen
                               oxides and VOCs.
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                               Stratospheric Ozone: In cooperation with industry,
                               AEERL evaluates, identifies, and recommends
                               substitute products and new industrial processes
                               which will replace ozone depleting substances that
                               are now in use. The current emphasis is on
                               alternatives for home and commercial refrigeration
                               systems.

                               Global Climate Change: This program is evaluat-
                               ing mitigation options for greenhouse gases
                               (carbon dioxide, methane, nitrous oxide) including
                               innovative technological solutions to the problem.
                               Also planned are inventories of emissions that are
                               contributing to global climate change.
Office of
Environmental
Processes and
Effects Research
    The Office of Environmental Processes and Effects
Research (OEPER) is responsible for the administra-
tion of a broad range of ecological research programs.
These programs are structured to provide the scientific
data and technological methods necessary to under-
stand the entry and movement of pollutants into the
environment and to determine the effects of such
substances on organisms and ecosystems. The informa-
tion and research products resulting from these
programs are directly applicable to fulfilling the
Agency's regulatory responsibilities.
    Research is conducted within the full realm of
environmental media—atmosphere, soil, ground water,
surface water, and coastal and marine waters. Major
areas of study include toxic substances, hazardous
waste, pesticides, acid deposition, biotechnology,
global climate change, stratospheric ozone, wetlands,
water quality, ecological risk assessment, and status of
critical ecological resources. The Office actively
provides technical support in environmental science
and technology to regions and states in order to assist
in problem solving and to transfer information and
technology to local users.

    The Robert S. Kerr Environmental Research
Laboratory (RSKERL) in Ada, Oklahoma, serves as
U.S. EPA's center for ground water research, focusing
its efforts on studies of the transport and fate of
contaminants in the subsurface, development of
methodologies for protection and restoration of ground-
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                            water quality, and evaluation of the applicability and
                            limitations of using natural soil and subsurface pro-
                            cesses for the treatment of hazardous wastes. Subsur-
                            face transport and fate information is incorporated into
                            mathematical models for use in predicting the transport
                            and fate of contaminants in the subsurface. Efforts to
                            support the immediate needs and activities of EPA's
                            operating programs are focused on the Underground
                            Injection Control Program, the Wellhead Protection
                            Program and the Hazardous Waste and Superfund
                            Programs. RSKERL's Technology Support Program
                            provides decision-makers with a source of information
                            on subsurface fate and transport of contaminants and
                            in situ remediation technologies, as well as the
                            associated expert assistance required to effectively use
                            this information.

                                The Environmental Research Laboratory in
                            Athens, Georgia, conducts and manages fundamental
                            and applied research, and  provides technical assistance/
                            technology transfer, required by the Agency to predict
                            the transformation, speciation, and transport of pollut-
                            ants across and within the air-water-soil-media. This
                            research is the foundation  for the development of risk-
                            based methodologies (1) to assess the potential
                            ecological and human exposures and risks associated
                            with conventional and toxic pollutants in the water-
                            sediment of aquatic/marine ecosystems and in soil
                            ecosystems, (2) to quantify the interactions of soil
                            ecosystems with and responses to global climate
                            change, and  (3) to design  and evaluate strategies for
                            soil-related remediation/risk reduction techniques, such
                            as nonpoint source control and contaminated soil
                            cleanup.
                                This research identifies and characterizes the
                            natural biological and chemical processes that deter-
                            mine the environmental fate and effects of specific
                            toxic substances, such as pesticides or metals. The
                            results are applied in state-of-the-art computer models
                            for assessing and managing environmental pollution
                            problems. Emphasized research areas in FY92 are
                            radiatively important trace (greenhouse) gas emissions
                            from temperate and tropical terrestrial/soil systems in
                            response to global climate change, ecological risk
                            assessment, sediment quality evaluation, artificial
                            intelligence-expert systems for predicting chemical


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                           reactivity, bioremediation, hazardous waste site
                           evaluation, and wellhead protection.
                               EPA's Center for Exposure Assessment Modeling
                           (CEAM), an internationally known center of modeling
                           expertise located at the Athens Lab, provides models,
                           training, and applications support for multimedia
                           exposure assessment related to remedial actions at
                           Superfund sites, for corrective actions at RCRA
                           facilities and for ecological exposure and risk assess-
                           ment support for pesticides, toxics, and general water
                           quality management

                               The Environmental Research Laboratory in
                           Corvallis, Oregon, conducts research on terrestrial and
                           watershed ecology and assesses the comprehensive
                           ecological impact of inland pollution and other
                           environmental changes caused by man. This includes
                           the ecological effects of airborne pollutants, such as
                           acid deposition; the ecological  effects of global climate
                           and UV-B changes; the effects of toxic chemicals on
                           terrestrial plants, animals, and ecosystems; the assess-
                           ment and restoration of contaminated or degraded
                           environments; the characterization and assessment of
                           the vulnerability of ecological systems such as wet-
                           lands, to human impacts; and the ecological risks from
                           the terrestrial release of bioengineered organisms and
                           other biological control agents.

                               The Environmental Research Laboratory in
                           Duluth, Minnesota, is primarily responsible for
                           developing water quality criteria and other measures  of
                           ecological health for the Nation's freshwaters. The
                           mission of this laboratory is to develop methods for
                           predicting and assessing the effects of pollutants and
                           pollution activities on freshwater resources. Located on
                           Lake Superior, the laboratory specializes in the
                           toxicology of industrial chemicals, pesticides, and
                           other hazardous substances.
                               Primary research programs include developing
                           ecosystem response models, diagnostic methods for
                           watersheds and  mass balance ecosystem models for the
                           Great Lakes. Studies of exotic  species, integration of
                           research data into EMAP, and  non-point pollution also
                           will be of high priority.
                               ERL-Duluth continues to conduct its research in
                           surface freshwater systems, both flowing and lakes,


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                            including the Great Lakes (Gross He, MI) and freshwa-
                            ter wetlands (Monticello, MN). Research programs
                            center on stresses from water criteria pollutants,
                            xenobiotics and biological stressors including climate
                            changes and sediments. Investigations focus on the
                            impact of these stresses through a risk assessment
                            framework including stressor source assessment,
                            classification/characterization, hazard identification and
                            stressor dose-response analysis.

                               The Environmental Research Laboratory at
                            Narragansett, Rhode Island, along with its Pacific
                            Coast laboratory in Newport, Oregon, is a National
                            Marine Water Quality Research Laboratory which has
                            been given expanded roles in sediment quality and
                            monitoring. The Laboratory's research and monitoring
                            efforts support primarily the EPA Office of Water,
                            Office of Emergency and Remedial Response, and the
                            Office of Air and Radiation. The Laboratory efforts
                            respond mainly to legislative requirements of the Clean
                            Water Act, the Marine Protection Act, Research
                            Sanctuaries Act, Clean Air Act, and the Superfund
                            Reauthorization Act. Major emphasis is placed on
                            providing the scientific base for environmental criteria,
                            waste disposal practices, environmental analysis and
                            impacts,  assessments of marine and estuarine risk of
                            regulatory activities by responsible offices.
                               The  principal research and monitoring themes of
                            the Laboratory reflect its major strengths and are
                            critical to accomplish the Laboratory's mission and the
                            Ecological Risk Assessment Program of the Agency.
                            The Laboratory's major themes are:  (1) Predictive
                            Biological Test Method Development, (2) Ecological
                            Processes and Significance, (3) Environmental Expo-
                            sure and Chemistry, and (4) Ecological Indicators and
                            Monitoring.
                               The  Laboratory is responsible for the following
                            research  and program areas: (1) marine and  estuarine
                            disposal, (2) water use designation and derivation of
                            criteria for marine and estuarine water and sediment,
                            (3) environmental assessment of ocean disposal and
                            discharges of waste and wastewaters, (4) technical and
                            research  support for evaluating remediation options at
                            proposed and designated marine/estuarine Superfund
                            sites, (5) research on the effects of global warming and
                            the depletion of stratospheric ozone on marine systems,
                            and (6) ecological monitoring for Near Coastal

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                           Ecosystems (EMAP). Technical assistance, technology
                           transfer, and investigations of an emergency nature,
                           e.g., spills of toxic materials, are also provided to aid
                           EPA offices in evaluating environmental threats posed
                           by toxicants, other pollutants, and physical modifica-
                           tions along our nation's coasts. Technical assistance is
                           also provided to other Federal  agencies, states, munici-
                           palities, and industry.

                                The Environmental Research Laboratory in Gulf
                           Breeze, Florida, has broad research objectives related
                           to the near-coastal marine environment which include
                           the development of scientific information for (1)
                           formulation of guidelines, standards, and strategies for
                           management of pesticides and  toxic chemicals in the
                           near-coastal marine environment, (2) definition of
                           current ecological "health" status and measurement and
                           prediction of changes in ecological structure and
                           function over time, (3) description of cause(s) of
                           aberrant conditions or observed changes in ecological
                           status, and (4) application of biological systems to
                           bioremediate toxic and hazardous chemicals in the
                           environment. Research is primarily devoted to chemi-
                           cal compounds and biological  products regulated by
                           EPA's Office of Pesticides and Toxic Substances, the
                           Office of Water Programs, and the Office of Solid
                           Waste and Emergency Response.
                                Research programs specifically addressed by the
                           Laboratory include (1) definition and evaluation of
                           factors and mechanisms that affect biodegradation rates
                           and bioaccumulation potential  in food-webs, (2)
                           development of procedures and evaluation protocols
                           for the biological  treatment of toxic chemicals and
                           hazardous wastes  in the environment, (3) determination
                           of effects  of carcinogens,  mutagens, and teratogens in
                           aquatic species, (4) development of principles and
                           applications of ecotoxicology,  including measurements
                           and predictions of the fate and effects of chemicals
                           and biotechnological products  on estuarine organisms,
                           populations, communities, and associated ecological
                           structure and function, (5) development and verifica-
                           tion of methods and data that allow extrapolation of
                           effects from laboratory observations to field situations,
                           within and among species, populations, communities,
                           and ecosystems, (6) development of methods to
                           evaluate the environmental risk of toxic chemicals and
                           products of biotechnology to the marine environment,

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                           (7) environmental monitoring and assessment of bays
                           and estuaries of the Gulf of Mexico to define ecologi-
                           cal "health" status and to define changes over time and
                           cause(s), and (8) development and evaluation of
                           procedures and chemical and biological products for
                           remediating spilled oil at sea or in coastal environ-
                           ments.
Office of
Exploratory
Research
    The Office of Exploratory Research (OER) is
responsible for planning, administering, managing and
evaluating EPA's exploratory research program in
general and, in particular, its extramural grant research
in response to Agency priorities as established by
Agency planning mechanisms. Its basic objective is to
support research aimed at developing a better basic
scientific understanding of the environment and its
inherent problems. OER accomplishes this objective
through several core programs: a Competitive Research
Grants Program, an Environmental Research  Centers
Program, a Hazardous Substance Research Centers
Program, a Visiting Scientists Program and a Small
Business Innovation Research Program. Separate
descriptions of these programs are provided elsewhere
in this research guide. In addition to the core programs,
OER administers other programs which are important
to the accomplishment of the OER objective. They
include:

•    A Minority Fellowship Program which awards
    fellowships to college seniors and graduate
    students enrolled on a full-time basis at Histori-
    cally Black Colleges and Universities and majoring
    in curricula that could be applied to the solution of
    environmental problems.

    A Minority Summer Intern Program which extends
    to recipients of fellowships under the Minority
    Fellowship Program the opportunity for hands-on
    experience in  the area of their academic  training
    by way of a summer internship at an EPA or other
    environmental facility. (Both the Minority Fellow- »
    ship Program  and the Minority Summer Intern
    Program are components of the Minority Institu-
    tions Assistance Program, which is briefly de-
    scribed elsewhere in this document)
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                              The Agency's Senior Environmental Employment
                              Program (SEE) which utilizes the skills and talents
                              of older Americans to meet employment needs of
                              environmental programs.

                              The Federal Workforce Training Program which
                              coordinates ORD's participation in workforce
                              training programs used by state and local govern-
                              ments.

                              The Experimental Program to Stimulate Competent
                              Research (EPSCoR) which attempts to stimulate
                              better research and researchers in those states that
                              have traditionally lacked a strong university-based
                              research effort and have, therefore, been relatively
                              unsuccessful at garnering federal research support.
Office of Health and
Environmental
Assessment
    The Office of Health and Environmental Assess-
ment (OHEA) is responsible for assessing the effects
of environmental pollutants in varying exposure
situations on human health and ecological systems and
determining the degree of risks from these exposures.
The risk assessments performed by OHEA are used by
the Agency as the scientific basis for regulatory and
enforcement decisions. OHEA's responsibilities also
include the development of risk assessment guidelines
and methodologies, and recommendations for new
research efforts that will better support future EPA risk
assessment activities and research that will reduce the
uncertainties in EPA risk assessment activities.
    Comprehensive methodologies are prepared for
health assessments of both single chemicals and
complex mixtures. Technical assistance to various
Agency programs and Regional Offices concerning
acceptable pollutant levels and dose-response relations
is also provided.
    The Office includes four organizational groups:

    The Human Health Assessment Group provides
state-of-the-art methodology, guidance, and procedures
on the health risks associated with suspected cancer-
causing agents and the risks associated with chemicals
that are suspected of causing detrimental reproductive
effects, including mutagenic, teratogenic, and other
adverse reproductive outcomes and reduced fertility;
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ORD  Organizational  Descriptions
                           assures quality and consistency in the Agency's
                           scientific risk assessments; provides advice on pro-
                           posed testing requirements for adequate risk assess-
                           ments; and prepares independent risk assessments.

                               The Exposure Assessment Group provides advice
                           on the exposure characteristics and factors of agents
                           that are suspected of causing detrimental health effects;
                           provides state-of-the-art methodology, guidance, and
                           procedures for exposure determinations; assures quality
                           and consistency in the Agency's exposure assessments,
                           and prepares independent assessments of exposure and
                           recommendations concerning the exposure potential of
                           specific agents.

                               The Environmental Criteria and Assessment Office
                           in Research Triangle Park, North Carolina, is respon-
                           sible for preparing air quality criteria documents and
                           air pollutant health assessment documents  for use in
                           Agency regulatory activities, as  well as legislatively
                           required health-related reports.

                               The Environmental Criteria and Assessment Office
                           in Cincinnati, Ohio, prepares health and hazard
                           assessment documents on water pollution and solid and
                           hazardous wastes and hazardous air pollutants.
Office Of Health             The Office of Health Research (OHR) is respon-
p        w                sible for developing and evaluating toxicity test
nesearcn                methods and for providing toxicity data to enable the
                           Agency to accurately identify hazards and determine
                           human risk from environmental exposure. To fulfill
                           this mission, research is conducted in three major
                           areas:
                               •   Toxicity test method development
                               •   Generation of dose-response data
                               •   Development of methods  to use data from
                                   toxicity testing and dose-response studies to
                                   estimate human morbidity and mortality;
                                   including  extrapolation from animal data to
                                   human effects, from high  to low doses, from
                                   acute toxicity to long-term effects, and from
                                   exposure to dose.
                               The Health Effects Research Laboratory (HERL)
                           in Research Triangle Park, North Carolina, conducts
                           research, both intramurally and extramurally, which is
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ORD Organizational Descriptions
                           responsive to these goals. Physical, biological and
                           chemical agents are studied; and research is conducted
                           in the scientific disciplines  of pulmonary toxicology,
                           genetic toxicology, neurotoxicology, developmental and
                           reproductive toxicology, and epidemiology and
                           biometry. Research to improve the quality of health
                           risk assessment is being conducted through the
                           development of pharmacokinetic and biologically based
                           models. These models are being developed to more
                           accurately predict the relationship between environ-
                           mental concentration, target tissue dose and ultimate
                           health effect
Office of Modeling,
Monitoring Systems
and Quality
Assurance
    The Office of Modeling, Monitoring Systems and
Quality Assurance (OMMSQA) is responsible for: (a)
research with respect to the characterization, transport,
and fate of pollutants which are released into the
atmosphere, (b) development and demonstration of
techniques and methods to monitor and model human
and ecological exposure and to relate ambient concen-
trations to exposure by critical receptors, (c) research,
development and demonstration of new monitoring
methods, systems, techniques, and equipment for
detection, identification and characterization of pollut-
ants at the source and in the ambient environment and
for use as reference or standard monitoring methods,
(d) management and oversight of the Agency-wide
quality assurance program, and (e) development and
provision of quality assurance methods, techniques and
material including validation and standardization of
analytical methods, sampling techniques, quality
control methods, standard reference materials, and
techniques for data collection, evaluation and interpre-
tation.
    The Environmental Monitoring Systems Laboratory
in Las Vegas, Nevada, conducts research and develops
programs related to: (a) monitoring of pollutants in the
environment, (b) developing sampling strategies and
techniques for monitoring hazardous waste leaches in
soil and groundwater,  (c) developing remote sensing
techniques,  (d) conducting human exposure monitoring
and modeling studies covering several environmental
media, (e) evaluating analytical methods for the
characterization and quantification of hazardous wastes,
and (f) providing quality assurance in support of the
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                            EPA's hazardous waste, Superfund, pesticides, ionizing
                            radiation, and acid deposition programs.

                                The Environmental Monitoring Systems Laboratory
                            in Cincinnati, Ohio, has as its primary mission: (a)
                            conducting research in the development, evaluation,
                            and standardization of chemical and biological methods
                            for environmental assessments, (b) conducting research
                            for detecting, identifying and quantifying microbial
                            pathogens found in environmental media, (c) providing
                            technical assistance to the program office and regions
                            for conducting bioassessments of aquatic systems, (d)
                            providing quality assurance in support of the wastewa-
                            ter, and related solid wastes, Superfund, and toxics
                            program.

                                The Atmospheric Research and Exposure Assess-
                            ment Laboratory in Research Triangle Park, North
                            Carolina, conducts intramural and extramural research
                            programs through laboratory and field research in
                            chemical, physical, and biological sciences to: (a)
                            characterize and  quantify present and future ambient
                            air pollutant levels and resultant exposures to humans
                            and ecosystems on local, regional, and global scales,
                            (b) develop and validate models to predict  changes in
                            air pollution levels and air pollutant exposures and
                            determine the relationships among the factors affected
                            by predicted and observed changes, (c) determine
                            source-to-receptor relationships relating to ambient air
                            quality and air pollutant exposures, developing predic-
                            tive models to be used for assessments of regulatory
                            alternatives derived from these relationships, directly or
                            indirectly, and (d) conduct long-term research in the
                            areas of atmospheric methods, quality assurance, field
                            monitoring, biomarkers, spatial statistics, exposure
                            assessment, human activity patterns, and modeling
                            research.
                                   127

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ORD Office/Laboratory
Abbreviations
CERI/CIN
ECAO/CIN
ECAO/RTP
EMSL/CIN
EMSL/LV
AREAL/RTP
RSKERL/ADA
ERL/ATH
Center for Environmental Research Information
  Cincinnati, OH 45268
  CML (513) 569-7391
  FTS 8-684-7391

Environmental Criteria and Assessment Office
  Cincinnati, OH 45268
  CML (513) 569-7531
  FTS 8-684-7531

Environmental Criteria and Assessment Office
  Research Triangle Park, NC 27711
  CML (919) 541-4173
  FTS 8-629-4173

Environmental Monitoring Systems Laboratory
  Cincinnati, OH 45268
  CML (513) 569-7301
  FTS 8-684-7301

Environmental Monitoring Systems Laboratory
  P.O. Box 93478
  Las Vegas, NV 89193-3478
  CML (702) 798-2100
  FTS 8-545-2100

Atmospheric Research and Exposure Assessment
Laboratory
  Research Triangle Park, NC 27711
  CML (919) 541-2106
  FTS 8-629-2106

Robert S. Kerr Environmental Research Laboratory
  P.O. Box 1198
  Ada, OK 74820
  CML (405) 332-8800
  FTS 8-743-2224

Environmental Research Laboratory
  College Station Road
  Athens, GA 30613
  CML (404) 546-3500
  FTS 8-250-3500
                               128

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ORD Office/Laboratory
Abbreviations
ERL/COR
ERL/DUL
ERL/GB
ERL/NARR
HERL/RTP
RREL/CIN
AEERL/RTP
OEETD/HQ
Environmental Research Laboratory
  200 SW 35th Street
  Corvallis, OR 97333
  CML (503) 757-4601
  FTS 8-420-4601

Environmental Research Laboratory
  6201 Congdon Boulevard
  Duluth, MN 55804
  CML (218) 727-6692
  FTS 8-780-5550

Environmental Research Laboratory
  Sabine Island
  Gulf Breeze, FL 32561
  CML (904) 934-9200
  FTS 8-228-9200

Environmental Research Laboratory
  South Ferry Road
  Narragansett, RI 02882
  CML (401) 782-3000
  FTS 8-838-6000

Health Effects Research Laboratory
  Research  Triangle Park, NC 27711
  CML (919) 541-2281
  FTS 8-629-2281

Risk Reduction Engineering Laboratory
  Cincinnati, OH 45268
  CML (513)  569-7418
  FTS 8-684-7418

Air and Energy Engineering Research Laboratory
  Research Triangle Park, NC 27711
  CML (919)  541-2821
  FTS 8-629-2821

Office of Environmental Engineering and
  Technology Demonstration
  (RD-681)
  Washington, DC 20460
  (202) 260-2600
                               129

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ORD Office/Laboratory
Abbreviations
OEPER/HQ
OER/HG
OHEA/HQ
OHR/HQ
OMMSQA/HQ
OTTRS/HQ
Office of Environmental Processes and Effects
  Research
  (RD-682)
  Washington, DC 20460
  (202) 260-5950

Office of Exploratory Research
  (RD-675)
  Washington, DC 20460
  (202) 260-5750

Office of Health and Environmental Assessment
  (RD-689)
  Washington, DC 20460
  (202) 260-7315

Office of Health Research
  (RD-683)
  Washington, DC 20460
  (202) 260-5900

Office of Modeling, Monitoring Systems and Quality
  Assurance
  (RD-680)
  Washington, DC 20460
  (202) 260-5767

Office of Technology Transfer and Regulatory Support
  (H-8105)
  Washington, DC 20460
  (202) 260-7669
                             130

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 ORD  Key Contacts
Abbott, Jim


Akland, Ann


Akland, Gerald


Beedlow, Peter


Benforado, Jay


Beny, Maurice


Berry, Michael


Birnbaum, Linda


Bishop, Fred


Black, Frank


Blaney, Benjamin


Bledsoe, Bert


Bond, Randall


Boyes, Williams


Brunner, Carl


Budde, William
CML (919) 541-3443
     FTS 8-629-3443

CML (919) 541-2883
     FTS 8-629-2883

CML (919) 541-2346
     FTS 8-629-2346

CML (503) 757-4634
     FTS 8-42O4634

CML (202) 260-7669
     FTS 8-260-7669

CML (513) 569-7284
     FTS 8-684-7284

CML (919) 541-4172
     FTS 8-629-4172

CML (919) 541-2655
     FTS 8-629-2655

CML (513) 569-7629
     FTS 8-684-7629

CML (919) 541-3037
     FTS 8-629-3037

CML (513) 569-7406
     FTS 8-684-7406

CML (405) 332-8800
     FTS 8-743-2324

CML (202) 260-5893
     FTS 8-260-5893

CML (919) 541-7538
     FTS 8-629-7538

CML (513) 569-7655
     FTS 8-684-7655

CML (513) 569-7309
     FTS 8-569-7309
Bufalni, Joseph


Burckte, John


Callahan, Clarence


Callahan, Michael


Calderon, Rebecca


Chapman, Robert


Clark, Robert


Clark, Thomas A.


Clements, John


Cogliano, James


Convery, John


Cook, Philip M.


Cordle, Steve


Cortesi, Roger


Costa, Charles


Costa, Daniel
CML (919) 541-2706
     FTS 8-629-2706

CML (513) 569-7506
     FTS 8-684-7506

CML (503) 757^651
     FTS 8^20-4764

CML (202) 260-8909
     FTS 8-260-8909

CML (202) 260-5893
     FTS 8-260-5893

CML (919) 966-6219
     FTS 8-629-6219

CML (513) 569-7201
     FTS 8-684-7201

CML (513) 569-7301
     FTS 8-684-7301

CML (919) 541-2188
     FTS 8-629-2188

CML (202) 260-2575
     FTS 8-260-2575

CML (513) 569-7601
     FTS 8-684-7601

CML (218) 720-5553
     FTS 8-780-5553

CML (202) 260-5940
     FTS 8-260-5940

CML (202) 260-5750
     FTS 8-260-5750

CML (702) 798-2305
     FTS 8-545-2305

CML (919) 541-2531
     FTS 8-629-2531
                                 131

-------
ORD  Key Contacts
Cote, Da
Craig, Alfred B.
Creason, John
Cupitt, Larry
Daniel, Bernie
Damey, Sally
CML (919) 541-3644
FTS 8-629-3644
CML (919) 541-2821
FTS 8-629-2821
CML (919) 541-2598
FTS 8-629-2598
CML (919) 541-2107
FTS 8-629-2107
CML (513) ,569-7411
FTS 8-684-74 11
CML (919) 541-3826
Ehrlich, Alan
Fairbrother, Anne
Farland, William
Farlow, John
Farrell, Joseph
Finkelstein, Pete
CML (202) 260-7315
FTS 8-260-7315
CML (503) 757-4651
FTS 8-420-4716
CML (202) 260-7315
FTS 8-260-7315
CML (201) 321-6635
FTS 8-340-6635
CML (513) 569-7645
FTS 8-684-7645
CML (919) 541-2347
                    FTS 8-629-3826

Dellarco, Michael  CML (202) 260-5794
                    FTS 8-260-5794

Dempsey, Clyde   CML (513) 569-7504
                    FTS 8-684-7504

DeRosa, Christopher
                CML (513) 569-7531
                    FTS 8-684-7531

desRosiers, Paul   CML (202) 260-2722
                    FTS 8-260-2722
Dick, Marshall


Donaldson, William



Dufour, Alfred


Dyer, Robert


Eaton, John
CML (202) 260-2583
    FTS 8-260-2583
CML (404) 546-3183
    FTS 8-250-3183

CML (513) 569-7218
    FTS 8-684-7218

CML (919) 541-2760
    FTS 8-629-2760

CML (218) 720-5557
    FTS 8-780-5557
Foley, Gary


Fowle, Jack


Freeman, Harry


Galli, Alfred


Carman, Jerry


Garrahan, Kevin


Graham, Judith


Grant, Lester


Graves, Robert


Grose, Elaine
    FTS 8-629-2347

CML (919) 541-2106
    FTS 8-629-2106

CML (919) 541-2479
    FTS 8-629-2479

CML (513) 569-7529
    FTS 8-684-7529

CML (202) 260-2583
    FTS 8-260-2583

CML (202) 260-7667
    FTS 8-260-7667

CML (202) 260-2588
    FTS 8-260-2588

CML (919) 541-0349
    FTS 8-629-0349

CML (919) 541-4173
    FTS 8-629-4173

CML (513) 569-7325
    FTS 8-684-7325

CML (919) 541-3844
    FTS 8-629-3844
                                132

-------
ORD Key  Contacts
Hall, Robert E.    CML (919) 541-2477
                     FTS 8-629-2477

Hangebrauck, R. P.
                 CML (919) 541-4134
                     FTS 8-629-4134

Harvey, Terence   CML (513) 569-7531
                     FTS 8-684-7531

Hedtke, Steven    CML (218) 727-5610
                     FTS 8-780-5610

Hem, Stephen     CML (702) 798-2594
                     FTS 8-545-2594

Hiatt, Michael     CML (702) 798-2381
                     FTS 8-545-2381

Highsmith, Ross   CML (919) 541-7828
                     FTS 8-629-7828

Hill, Ronald D.    CML (513) 569-7546
                     FTS 8-684-7546

Hiustick, Dwight   CML (202) 260-5776
                     FTS 8-260-5776

Hogsett, William   CML (503) 755^632
                     FTS 8-420-4632

Howard, Barry     CML (919) 541-5208
                     FTS 8-629-5208

Hurst, Pei-Fung    CML (513) 569-7585
                     FTS 8-684-7585

James, Steven      CML (513) 569-7877
                     FTS 8-684-7877

Jaworski, Norbert A.
                 CML (401) 782-3000
                     FTS 8-838-6000

Jones, Bruce       CML (702) 798-2671
                     FTS 8-545-2671
Jones, Julian      CML (919) 541-2489
                     FTS 8-629-2489

Kapustka, Lawrence
                CML (503) 757-4606
                     FTS 8-420-4606

Kavlock Robert   CML (919) 541-2326
                     FTS 8-629-2326

Keith, William    CML (202) 260-5776
                     FTS 8-260-5776
Kibby, Hal
CML (503) 757-4625
    FTS 8-420-4625
Klauder, David    CMS (202) 260-7667
                     FTS 8-260-7667
Klee, Al
CML (513) 569-7493
    FTS 8-684-7493
Kleffman, David  CML (202) 260-5900
                     FTS 8-260-5900

Knapp, Kenneth   CML (919) 541-3085
                     FTS 8-629-3085

Koglin, Eric      CML (702) 798-2237
                     FTS 8-545-2237

Kreissl, James    CML (513) 569-7611
                     FTS 8-684-7611

Krishnan, Bala    CML (202) 260-2613
                     FTS 8-260-2613

Kutz, Frederick W.
                CML (202) 260-5776
                     FTS 8-260-5776

Lackey, Robert    CML (503) 757-4601
                     FTS 8-420-4601

Landers, Dixon    CML (503) 727-4427
                     FTS 8-420-4427
                                 133

-------
 ORD Key Contacts
Landreth, Robert E.



Laveille, Will C.


Laws, Ken


Lazorchak, James


Leach, Lowell


LeDuc, Sharon


Lee, Henry


Lee, Robert E.


Levinson, Barbara


Lewtas, Joellen


Lindsey, Alfred


Lykins, Ben


MacPhail, Robert


Matthews, John E.


Maxwell, Michael
CML (513) 569-7871
    FTS 8-684-7871

CML (202) 260-5990
    FTS 8-260-5990

CML (919) 541-5744
    FTS 8-629-5744

CML (513) 569-8114
    FTS 8-684-8114

CML (405) 332-8800
    FTS 8-743-2333

CML (919) 541-1335
    FTS 8-629-1335

CML (503) 867-4042
    FTS 8-430-4042

CML (919) 541-2454
    FTS 8-629-2454

CML (202) 260-5983
    FTS 8-260-5983

CML (919) 541-3849
    FTS 8-629-3849

CML (202) 260-4073
    FTS 8-260-4073

CML (513) 569-7460
    FTS 8-684-7460

CML (919) 541-7833
    FTS 8-629-7833

CML (405) 332-8800
    FTS 8-742-2233

CML (919) 541-3091
    FTS 8-629-3091
                    McCarthy, Bill
                CML (202) 260-2605
                    FTS 8-260-2605
McElroy, James L. CML (702) 798-2361
                    FTS 8-545-2361
McKee, Gerald
CML (513) 569-7303
    FTS 8-684-7303
McKinney, James  CML (919) 541-3585
                    FTS 8-629-3585

McKinnon, Hugh  CML (202) 260-5898
                    FTS 8-260-5898

McNabb, James F. CML (405) 332-8800
                    FTS 8-743-2216
Meier, Eugene


Menzer, Robert


Miller, Thomas
CML (702) 798-2237
    FTS 8-545-2237

CML (904) 934-9200
    FTS 8-228-9011

CML (202) 260-5891
    FTS 8-260-5891
Mitchell, William  CML (919) 541-2769
                    FTS 8-629-2769
Moore, Martha


Moore, Michael


Mulkey, Lee A.


Mullin, Cynthia
CML (919) 541-3933
    FTS 8-629-3933

CML (202) 260-7671
    FTS 8-260-7671

CML (404) 546-3546
    FTS 8-250-3546
CML (513) 569-7523
    FTS 8-684-7523
Murphy, Thomas A.
                CML (503) 757-4601
                    FTS 8-420-4601
                                 134

-------
 ORD Key Contacts
Nalesnik, Richard P.
                CML (202) 260-2583
                     FTS 8-260-2583

Nelson, William G. CML (401) 782-6001
                     FTS 8-838-6053

Nesnow, Stephen  CML (919) 541-3847
                     FTS 8-629-3847

Oberacker, Donald CML (513) 569-7510
                     FTS 8-684-7510

Olexsey, Robert   CML (513) 569-7861
                     FTS 8-684-7861

Olson, Richard    CML (503) 757-4666
                     FTS 8-420-4666

O'Neil. John      CML (919) 966-6200
                 FTS 8-919-966-6200

Oppelt, Timothy.  CML (513) 569-7896
                     FTS 8-684-7896
Pahl, Dale
CML (919) 541-1851
    FTS 8-629-1851
Papa, Linda R.    CML (513) 569-7587
                     FTS 8-684-7587

Parish, Rod      CML (904) 934-9221
                     FTS 8-228-9221

Patton, Dorothy   CML (202) 260-6743
                     FTS 8-260-6743
Paul, John


Paur, Dick
CML (401) 782-6037
    FTS 8-838-6037

CML (919) 541-3131
    FTS 8-629-3131
Pearson, Gareth   CML (702) 798-2203
                    FTS 8-545-2203
Peirano, Bruce    CML (513) 569-7540
                     FTS 8-684-7540

Perlin, Susan     CML (202) 260-5891
                     FTS 8-260-5891

Pitchford, Marc   CML (702) 798-2363
                     FTS 8-545-2363

Plyler, Everett    CML (919) 541-2918
                     FTS 8-629-2918

Preston, Walter   CML (202) 260-7445
                     FTS 8-260-7445

Preuss, Peter     CML (202) 260-7669
                     FTS 8-260-7669

Pritchard, Hap    CML (904) 934-9260
                     FTS 8-228-9260

Puzak, Jack      CML (202) 260-5767
                     FTS 8-260-5767

Radzikowski, Mary Ellen
                CML (202) 260-5891
                     FTS 8-260-5891

Reiter, Larry     CML (919) 541 -2281
                     FTS 8-629-2281

Rhodes, William  CML (919) 541-2853
                     FTS 8-629-2853

Ringold, Paul     CML (202) 260-5609
                     FTS 8-260-5609

Riordan, Courtney CML (202) 260-5950
                     FTS 8-260-5950

Rogers, Charles   CML (513) 569-7757
                     FTS 8-684-7757

Rossman, Lewis   CML (513) 569-7603
                     FTS 8-684-7603
                                 135

-------
 ORD Key Contacts
Royer, Michael   CML (201) 321-6633   Stelz, Bill.        CML (202) 260-5776
                     FTS 8-340-6633                       FTS 8-260-5776

Russo, Rosemarie, C.                    Stevens, Al       CML (513) 569-7342
                CML (404) 546-3500                       FTS 8-684-7342
                     FTS 8-250-3500
                                     Swank, Robert     CML (404) 546-3500
Saint, Chris      CML (202) 260-5776                       FTS 8-250-3500
                     FTS 8-260-5776
                                     Tang, Don        CML (202) 260-2621
Sala, Ken        CML (202) 260-5776                       FTS 8-260-2621
                     FTS 8-260-5776
                                     Thomas, Nelson    CML (218) 720-5702
Sanville, William  CML (218) 720-5723                       FTS 8-780-5702
                     FTS 8-780-5723
                                     Tilson, Hugh      CML (919) 541-2671
Schiermeier, Francis                                         FTS 8-629-2671
                CML (919) 541-4542
                     FTS 8-629-4542   Tingey, Dave      CML (503) 757-4621
                                                         FTS 8^20-4621
Schuda, Laurie    CML (202) 260-5776
                     FTS 8-260-5776   Tucker, W. Gene   CML (919) 541-2746
                                                         FTS 8-629-2746
Selgrade, Mary Jane
                CML (919) 541-2657   Vanderberg, John   CML (919) 541-4527
                     FTS 8-629-2657                       FTS 8-629-4527

Sexton, Ken      CML (202) 260-5900   Veith, Oilman     CML (218) 720-5500
                     FTS 8-260-5900                       FTS 8-780-5500

Shreffler, Jack    CML (919) 541-2194   Vickery, James     CML (919) 541-2184
                     FTS 8-629-2194                       FTS 8-629-2184

Sickles, Joe      CML (414) 541-2446   Walker, Henry A.   CML (401) 782-3134
                     FTS 8-629-2446                       FTS 8-838-6134

Sigmon, John T.   CML (202) 260-5738   Waters, Michael    CML (919) 541-2537
                     FTS 8-260-5738                       FTS 8-629-2537

Snelling, Robert   CML (702) 798-2525   Wentworth, Nancy  CML (202) 260-5763
                     FTS 8-545-2525                       FTS 8-260-5763

Sommers, Kevin   CML (904) 934-9244   Wiles, Carlton     CML (513) 569-7795
                     FTS 8-228-9244                       FTS 8-684-7795

Sorg,Tom        CML (513) 569-7370   Williams, Bill A.   CML (503) 757-4679
                     FTS 8-684-7370                       FTS 8-420-4679

                                136

-------
ORD Key Contacts
Wilmoth, Roger


Wilson, John J.


Wilson, William


Winter, John


Wolfe, Lee


Worlund, John


Worrest, Robert


Wu, Chieh


Zenick, Harold
CML (513) 569-7509
    FTS 8-684-7509

CML (405) 332-8800
    FTS 8-743-2259

CML (919) 541-2551
    FTS 8-629-2551

CML (513) 569-7325
    FTS 8-684-7325

CML (404) 546-3429
    FTS 8-250-3429

CML (702) 798-2656
    FTS 8-545-2656

CML (202) 260-5981
    FTS 8-260-5981

CML (202) 260-5977
    FTS 8-260-5977

CML (919) 541-2281
    FTS 8-629-2281
                              137

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ORD Regional Contacts
    The Office of Research and Development's Regional Operations Staff is respon-
sible for planning, coordinating, and reviewing programs that provide inter-communi-
cation and assistance on all matters of mutual interest and/or responsibility of the
Agency's Regional Offices and the Office of Research and Development
Director, David Klauder                                  CML (202) 260-7667
Regional Operations Staff (RD-672)                            FTS 8-260-7667
Washington, DC 20460

Regional Liaison Officer, Glenn Williams                    CML (202) 260-7667
Regional Operations Staff                                     FTS 8-260-7667
Washington, DC 20460

Coordinator, Regional Scientist
    Program, Ron Landy                                 CML (202) 260-7667
Washington, DC 20460                                       FTS 8-260-7667

Coordinator, Regional Superfund                           CML (202) 260-7667
    Technical Liaison Program                               FTS: 8-260-7667
Jerry Carman
Washington, DC 20460

ORD/OTTRS Regional Scientists

Thomas Waddell, Region I                                CML (617) 565-3397
Boston, MA 02203                                          FTS 8-835-3397

Suzanne Lussier, Region III                               CML (215) 597-1177
Philadelphia, PA 19107                                       FTS 8-597-1177

John Montanari, Region IV                                CML (404) 347-7109
Atlanta, GA 30365                                          FTS 8-257-7109

Norman Dyer, Region VI                                 CML (214) 655-2252
Dallas, TX 75270                                            FTS 8-255-2252

Winona Victery, Region IX                                CML (415) 744-1021
San Francisco, CA 94103                                     FTS 8^84-1021

Randall J.F. Bruins, Region  X                             CML (206) 533-2146
Seattle, WA 98101                                          FTS 8-399-2146
                                 138

-------
ORD  Regional Contacts
Superfund Technkal Liaisons

Steve Mangion, Region I
Boston, MA 02203

Magalie Breville, Region II
New Yoik, NY 10278

Norm Kulujian, Region in
Philadelphia, PA 19107

John Risher, Region IV
Atlanta, GA 30365

Jack Barnette, Region V
Chicago, IL 60604

Robert L. Stone, Region Vffl
Denver, CO 80202-2405

Joe Greenblott, Region IX
San Francisco, CA 94105

John Barich, Region X
Seattle, WA 98101
CML (617) 573-5718
    FTS 8-833-1718

CML (212) 264-6788
    FTS 8-264-6788

CML (215) 597-1113
    FTS 8-597-1113

CML (404) 347-1586
    FTS 8-257-1586

CML (312) 886-8963
    FTS 8-886-8963

CML (303) 294-7597
    FTS 8-330-7597

CML (415) 744-2307
    FTS 8-484-2307

CML (206) 553-8562
    FTS 8-399-8562
                              139

-------
EPA Regional  Offices
   Region 1       Environmental Protection Agency
                  Room 2203
                  John F. Kennedy Federal Building
                  Boston, Massachusetts 02203
                  CML (617) 565-3424
                  FTS 8-835-3424

   Region 2       Environmental Protection Agency
                  Room 900
                  26 Federal Plaza
                  New York, New York 10278
                  CML (212) 264-2515
                  FTS 8-264-2515

   Region 3       Environmental Protection Agency
                  841  Chestnut Street
                  Philadelphia, Pennsylvania 19107
                  CML (215) 597-9370
                  FTS 8-597-9370
   Region 4       Environmental Protection Agency
                  345 Courtland Street, NE
                  Atlanta, Georgia 30365
                  CML (404) 347-4727
                  FTS 8-257-3004
   Region 5       Environmental Protection Agency
                  230 South Dearborn Street
                  Chicago, Illinois 60604
                  CML (312) 353-2072
                  FTS 8-353-2072
   Region 6       Environmental Protection Agency
                  1445 Ross Avenue
                  12th Floor, Suite 1200
                  Dallas, Texas 75202
                  CML (214) 655-2200
Connecticut
Maine
Massachusetts
New Hampshire
Rhode Island
Vermont

New Jersey
New York
Puerto Rico
Virgin Islands
Delaware
District of Columbia
Maryland
Pennsylvania
Virginia
West Virginia

Alabama
Florida
Georgia
Kentucky
Mississippi
North Carolina
South Carolina
Tennessee

Illinois
Indiana
Michigan
Minnesota
Ohio
Wisconsin

Arkansas
Louisiana
New Mexico
Oklahoma
Texas
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   Region 7       Environmental Protection Agency
                  726 Minnesota Avenue
                  Kansas City, Kansas 66101
                  CML (913) 551-7003
                  FTS  8-276-7003

   Region 8       Environmental Protection Agency
                  999 18th Street
                  Suite 500
                  Denver, Colorado 80202-2405
                  CML (303) 293-1692
                  FTS 8-330-7665

   Region 9       Environmental Protection Agency
                  75 Hawthorne
                  San Francisco, California 94105
                  CML (415) 744-1305
                  FTS 8-484-1305
  Region 10       Environmental Protection Agency
                  1200 Sixth Avenue
                  Seattle, Washington 98101
                  CML (206) 442-1107
                  FTS 8-399-1107
Iowa
Kansas
Missouri
Nebraska
Colorado
Montana
North Dakota
South Dakota
Utah
Wyoming

Arizona
California
Hawaii
Nevada
Guam
American Samoa

Alaska
Idaho
Washington
Oregon
•US. GOVERNMENT PRINTING OFFICE; 1991- "••-
                                       tOSZi
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