United States
          Environmental Protection
          Agency
Office of Research and
Development
Washington DC 20460
EPA/600/K-95/001
April 1995
4>EPA    Research and Development
          1994 Research
          Accomplishments

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Introduction

    EPA is one of a few federal organizations that function both as
a science agency and a regulatory agency. The challenge for the
Agency's research arm, the Office of Research and Development
(ORD), has been to provide information and technical support for
federal, state, and local officials facing today's environmental
problems and, at the same time, to expand the science and technol-
ogy base needed for solving problems in the future.
    In its 20-year history, ORD has developed, refined, and dis-
seminated much of the basic technical know-how employed by
EPA, other federal agencies, states, cities, industry, and others to
protect our natural resources. For example, ORD laboratories
developed many of today's basic methods for mapping complex
ecological processes and assessing adverse effects from pollutants.
They developed and continue to upgrade much of the standard
sampling and analytical equipment necessary for directing effec-
tive pollution control efforts. They have  revolutionized faster, more
cost-effective technologies for disinfecting drinking water, reduc-
ing toxic air emissions, and cleaning up  hazardous waste and oil
spills.
    ORD's scientists and engineers work closely with decision-
makers to translate knowledge into action. Often in crisis
situations, ORD experts have lent technical assistance in control-
ling environmental problems. ORD scientists provided critical
scientific knowledge to help assess environmental damage from the
Kuwaiti oil fires, to help Eastern Europe clean up decades of air
and water pollution, to help the U.S. and Canada restore the Great
Lakes, and to help cities  in the U.S. and  South America control
outbreaks of disease from microscopic drinking  water parasites.
    As a way to decide where to focus attention and resources on
diverse and seemingly unlimited problems, the Agency uses the
risk assessment/risk management
framework described by  the National
Research Council in its report, Risk
Assessment in the Federal Govern-
ment: Managing the Process, 1983.
This framework helps to identify
research that will have the greatest
impact on increasing our understand-
ing of the risks from pollutants and
ways to prevent, reduce,  or cleanup
pollution. Better understanding of
risks and ways to manage them helps
to identify the areas of greatest need
and to let us tackle the worst prob-
lems first.
This spinning top aerosol
generator is used to
characterize inlet efficiencies
of sampling instruments.

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The risk paradigm shows the
relationship of each component
of the risk assessment process
and how each contributes to
regulatory and policy
decisions.
                                       The basic scientific questions surrounding risk assessment and
                                   risk management are grouped into four categories:
                                       4-  effects
                                       +  exposure
                                       4-  assessment
                                       4  management, i.e., prevention, reduction, and remediation.
                                       The first area, effects research, considers questions about
                                   pollutants in the environment and whether they cause harm.
                                   Methods are developed for use by EPA and others to detect those
                                   pollutants that have the capacity to cause a variety of health and
                                   ecological effects. Studies are conducted or analyzed to determine
                                   how much of a pollutant can cause those effects.
                                       The next area, exposure assessment, determines what pollut-
                                   ants are in the environment, at what levels, where they go, and
                                   what happens along the way.
                                       The third area, risk assessment, integrates information from
                                   the first two areas of research to estimate the likelihood and
                                   magnitude of impact from pollutants. Research also develops
                                   methods  and models to reduce uncertainties in the risk assessment
                                   process.
                                       The fourth area, risk management, determines the alternative
                                   solutions and associated costs. Activities include development of
                                   industrial processes that prevent pollution. A significant percentage
                                   of the Agency's resources have  funded research to reduce risks,
                                   particularly from air and water pollution. Finally, independently
                                   and in collaboration with others, the Agency  develops technology
                                   for cleaning up past environmental damage such as that found at
                                   waste sites and protecting the environment from pollutants being
                                   released today.
                                       This report illustrates the kind of science questions ORD
                                   researches in each of the four categories and  highlights accom-
                                   plishments from fiscal year 1994.
                                         RISK ASSESSMENT / RISK MANAGEMENT
                                          /  Dose-Response  \
                                               Assessment
                              Technology

                     /\ Socioeconomic

                                                                       Factors
                                           Hazard
                                        Identification
                    [Riskl   	>.    Regulatory
               Characterization      Policy Decision
      Exposure
\   Assessment   /
\  /    Public  /
 Y   Perception
    X    Cost/Benefit

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Effects
    Research about the effects of pollutants on humans and ecosys-
tems includes hazard identification and dose-response assessment.
Hazard identification involves gathering and evaluating data about
the types of health problems or diseases (e.g., cancer) that affect
humans or the impacts on ecosystems that can be caused by a
chemical or a pollutant.
    Dose-response research addresses questions about how much
of a chemical humans or plant and animal species have to be
exposed to before they are affected and what is the type and
magnitude of the effect. Notable effects research in FY 1994
includes the following:

Sulfate Effects Data for Revised  Drinking Water
Standard
    EPA is  reevaluating the current standard for sulfate levels in
    drinking water. Data on sulfate, which can cause diarrhea in
    children and adults, were available only from reports of
    individual cases. To fill the data gap, EPA's Health Effects
    Research Laboratory in Research Triangle Park (RTP), North
    Carolina, conducted animal and human studies to determine
    the dose at which effects would be seen for both infants and
    adults. ORD has been able to provide hard data on what doses
    produce adverse effects for judging the adequacy of the current
    standard.
Methanol Health Effects for Decisions on Fuel
Additives
    Scientists at EPA's Health Effects Laboratory in RTP,
    North Carolina, continued studying the health effects from
    exposure to methanol. Mouse studies are producing
    information on birth defects caused by methanol exposure
    as well as the dose and duration of exposure that causes
    defects. Findings have been published in journals, and
    future work in this area will address the similarities of
    methanol sensitivity between mice and humans in order to
    improve the scientific basis of conclusions about human
    effects drawn from mouse studies.

New Methods  Promise Faster Toxicity Tests
    ORD researchers at EPA's laboratory in Gulf Breeze,
    Florida, developed and validated a technique that prom-
    ises to give scientists a faster, less costly way to identify
    chronic toxic effects from water pollutants. The method
    extrapolates chronic effects from acute effects, and could
    reduce from 28 days to two days the time needed for
A research biologist examines
negatives ofDNA as detected
in rodent cells after exposure
to pollutants.

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    assessing long-term health effects of pesticides and metals in
    runoff from agricultural and urban areas.


    ORD revised and updated the manuals used as the basic
    technical guides by government and industry in testing dis-
    charges from sewers, holding tanks, and other sources to
    ensure that the amounts of potentially toxic materials released
    into streams,  rivers, and estuaries stay within safe limits for
    fish and other marine life. ORD also developed a new
    generation of computer software to make it easier and faster
    for users to analyze data from the tests. Companies, cities, and
    states all across the U.S. rely on the sound, standardized results
    of these tests  for seeking and granting permits under funda-
    mental federal and state rules.

Health Concerns About  Carpets Clarified

    Scientists at EPA's Health Effects Research Laboratory in RTF,
    North Carolina, completed a study that has filled a critical data
    gap in our understanding of the health effects of carpet
    emissions. A commercial animal-testing facility produced a
    study that linked exposure to carpet emissions to serious heart
    and nervous system conditions and even death.  However,  ORD
    researchers could not replicate the  reported test results and
    concluded that the facility's methodology was valid for testing
    for irritation effects but not for evaluating serious health
    effects.  ORD's study has been used by judges when ruling on
    the use of animal tests in court cases where consumers are
    suing carpet manufacturers for alleged serious health problems.

EMAP Measures Ecological Conditions  Across the
Country
    The Environmental Monitoring and Assessment Program
    (EMAP) is an applied monitoring and assessment program
    designed to describe the condition  of our nation's ecological
    resources. In  FY1994, an Arctic EMAP Program has been
    established with the State of Alaska to study arctic
    environmental contamination and train  Russian scientists  in
    EMAP approaches. EMAP also has generated data for
    describing the conditions of Northeastern lakes and evaluating
    effects from acid deposition. Under EMAP estuaries research,
    scientists have designed long-term monitoring plans, collected
    environmental samples, and conducted  statistical analyses for
    the Chesapeake Bay, the Gulf of Mexico, Puget Sound,
    Long Island Sound, Delaware Bay, Tampa Bay, Sarasota Bay,
    Galveston Bay, Corpus Christi Bay, and Santa Monica Bay.

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Global Change Research
    The possibility of global change raises many scientific ques-
    tions about the effects of climate change on activities such as
    farming, the decrease in the capacity of the ozone layer to
    shield the earth from ultraviolet radiation, and the health and
    ecosystem effects of increased exposure to ultraviolet radia-
    tion.

    Nationally and internationally, ORD is studying the impact of
    farming, conservation, and other land uses on global climate
    change and, conversely, the impact of climate changes on
    agricultural
    resources. For
    example, an ORD
    study of the
    practice of leaving
    crop residue such
    as corn stalks on
    the ground to
    prevent soil
    erosion found that
    the practice also
    holds carbon in the
    soil, which helps
    reduce atmospheric
    levels  of green-
    house  gases. By
    quantifying this
    carbon retention,
    and extrapolating
    carbon levels that
    would be retained
                                        Potential rice yield changes
                                        predicted by computer model.
% change in  rice  yield predicted by ORYZA with GISS  data
   0 -36 to -28             0 -9 to -1             en 7 to 12
   • -27 to -19             Do                0 13 to 18
   en -18 to -10             CH 1 to 6             CH 19 to 25
    by alternative
    practices, ORD has
    reduced uncertain-
    ties about the role of harvested fields in global change
    equations.

    As part of a multi-year study to understand how ultraviolet
    radiation makes people more susceptible to different kinds of
    infections, ORD's Health Effects Research Laboratory identi-
    fied a strain of laboratory mice that has similar mechanisms of
    immune system suppression as those found in people. Conse-
    quently, laboratory studies using these mice may be a faster,
    less expensive way than human epidemiological studies for
    determining whether increased levels of UV-B pose a risk to
    the human immune system.

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Photo by S.C. Delaney / U.S. EPA
                                  Exposure
    Research to understand what pollutants are released into the
environment, where they go in the environment, and what happens
to them along the way is the focus of EPA's exposure research.
Notable efforts in FY 1994 include:

"Living Room" Lab Measures Indoor Pollution
    At its laboratories in RTF, North Carolina, ORD has built a
    room-sized  laboratory chamber (one of only four in the world)
    to study and define emissions from paint, fabrics, furnishings,
    and other items typically found inside offices and houses.
    Using precise, sophisticated equipment, ORD simulates typical
    indoor exposures to pollutants under varying temperatures,
    humidity, and air flows, and then measures the environmental
    levels of contaminants under those conditions. These findings
    significantly reduce the uncertainty associated with complex,
    often subtle exposures to indoor air pollution, providing
    government, industry, and others with sound data for making
    well-reasoned decisions. Among further benefits, the chamber
    can be used by the private sector to test emissions from new
    products under real conditions, can be used to standardize
    testing procedures (thereby reducing confusion and promoting
    consistent data), and can be used to demonstrate the effective-
    ness of air cleaning devices.

Effects of Wind  Borne Pesticides Studied
    Scientists at ORD's Environmental Research Laboratory in
    Athens, Georgia, formed a government/industry consortium to
    evaluate the environmental problems caused by sprayed
    pesticides that drift on the wind into nearby fields,  lakes, and
                                  streams. By linking industry
                                  data, EPA's exposure mod-
                                  els,  and U.S.  Department of
                                  Agriculture's field studies,
                                  the consortium will develop
                                  a validated assessment tool
                                  to evaluate the risk of offsite
                                  drift, identify the right
                                  parameters for measuring
                                  pesticide drift, and estimate
                                  the amount of drift under
                                  different conditions. This
                                  consortium will help develop
                                  methods for evaluating the
                                  potential risks from pesticide
                                  spraying.

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New Technique Identifies Ozonation  Byproducts
    Responding to concerns that chlorination may create poten-
    tially harmful by-products when it reacts with certain kinds of
    organic matter in drinking water, ORD scientists have led
    research to evaluate ozonation as an alternative treatment to
    reduce the amount of chlorine needed for disinfection. In
    FY94, ORD also pioneered the development of new analytical
    methods that will help scientists assess whether ozonation
    itself creates by-products that would be of equal or greater
    concern. Applying specialized expertise, ORD researchers
    combined two techniques, mass spectroscopy and infrared
    spectroscopy, to identify for the first time some 20 different
    ozonation by-products in water containing high natural con-
    centrations of bromide. The ORD findings, developed in
    collaboration with the University of North Carolina, also
    provide new insight into the complex processes that create the
    by-products.

ORD Tests Methods for National Human
Exposure Study
    In FY94, ORD signed agreements with three research consor-
    tia as a first step in launching the National Human Exposure
    Assessment Study (NHEXAS), a long-term "report card" that
    for the first time will give decision-makers  consistent, nation-
    wide information on human exposure to pollutants. Under the
    agreements, the consortias of universities and other not-for-
    profit research organizations are testing the concepts, methods,
    and approaches that are proposed for the long-term study.
    These pilot studies will provide sound building blocks for the
    innovative long-term effort.

Model  Predicts Natural Sources of Smog
    The  atmospheric chemis-
    try models that cities and
    regions currently use to
    estimate smog levels and
    to demonstrate attainment
    of the ozone standard
    include estimates of how
    much natural sources can
    contribute to these levels.
    Isoprene from trees, for
    example, reacts very
    quickly with other
    chemicals in the air to
    form smog. Scientists at
Atlanta skyline.

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    EPA's Air and Energy Engineering Laboratory and the Atmo-
    spheric Research and Exposure Assessment Laboratory in RTF,
    North Carolina, have developed a new model for estimating
    emissions from natural sources. The model, tested in Atlanta
    where there is light industry but large surrounding forests,
    predicted emissions that more closely matched measured
    concentrations. Because emissions from natural sources
    contribute significantly to ozone formation, they have to be
    factored into any strategy for meeting the ozone standard. This
    improved model will contribute to more cost-effective and
    realistic strategies for fighting smog.

Risk  Assessment

    To assess the risks of environmental contaminants, ORD
scientists integrate the results and data from exposure and effects
studies conducted in-house and by other public and private science
organizations. However, the gaps in our knowledge result in
uncertainties in the risk assessments. Scientists in ORD's research
program address these knowledge gaps in both human health and
ecosystem effects and develop the risk assessments that are then
incorporated into Agency decisions.

Dioxin Reassessment Focuses Attention on
Noncancer Effects
    Scientists with EPA's Office of Health and Environmental
    Assessment and the Health Effects Research Laboratory in
    RTF,  North Carolina, completed the external review drafts of
    EPA's reassessment of dioxin, which include research results
    on dioxin's noncancer effects on the immune, reproductive,
    and neurological systems. These drafts, the results of a 3-year
    effort, reaffirm the link between dioxin and cancer and con-
    clude that dioxin exposure at some level may result in a
    number of noncancer health effects in humans. The reassess-
    ment also identifies sources of dioxin known to contribute to
    environmental contamination.

New Fuel Additives Raise Questions of Health
Effects
    Recent legislation encourages the development and use of
    reformulated gasolines and alternative fuels. ORD's program
    in this area evaluates additives or alternative fuels for their
    health effects. In FY1994, ORD conducted research and risk
    assessments as a result of questions raised by the State  of
    Alaska and others about the health effects of MTBE, a gasoline
    additive that helps reduce carbon monoxide and the hydrocar-
    bons  that form ozone. ORD organized a joint

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    government-industry research program for a health risk
    assessment. Based on the uncertainties identified in the assess-
    ment, ORD is continuing research and assessment of MTBE
    and other compounds.

Extensive Health Effects Research Included in
Assessment of Ozone
    ORD research conducted in the past several years on the
    human health effects of ozone shows that exposure to ozone at
    concentrations below the current standard can cause significant
    pulmonary dysfunction—difficult breathing, coughing, and
    chest pain. Pulmonary dysfunction can occur even after
    exposure for only several hours and, appears to have long
    lasting effects. Research findings have been reported in 30
    journal articles in FY1994 and ORD scientists contributed
    significantly to the Agency's consideration of revising the
    current standard. In addition, scientists from EPA's Health
    Effects Research Laboratory in RTP, North Carolina, recently
    authored the World Health Organization's Guidelines for
    Ozone.
Advances in Ecological Assessment
    Risks to ecosystems from pollution are also
    important to understand and characterize. Changes
    to ecosystems can affect the condition and quantity
    of our natural resources, food production and
    supplies, and nature's ability to "heal itself or
    recover from negative environmental effects.
    Highlights from EPA's FY1994 research in
    "ecorisk assessment" include the following
    developments:
    Scientists at EPA's Environmental Research
    Laboratory in Duluth, Minnesota, have developed
    3-D computer technology that simulates the
    accumulation of chemicals in fish. The 3-D
    technique explains relatively sophisticated prin-
    ciples of chemical accumulation and species
    extrapolation in an easily understood way. This
    project can be applied to all areas of toxicology
    and risk assessment that use models to describe
    how chemicals accumulate in organisms.

    At EPA's Environmental Research Laboratory in
    Corvallis, Oregon, scientists completed an interim
    assessment of risk to forests from ozone. This
             These 3-D computer-generated
             graphics show chemical
             accumulation in fish at 2-hour (a)
             and 4-hour (b) exposures. The
             chemical accumulation after 4
             hours is shown, in descending
             order, by the bright red hue of the
            fat layer, the kidney, the
             intestines, and the liver.
 pentachlorethane (jig/kg)
                               hour 2
0.0    20.0    40.0    60.0    80.0    100.0
 pentachlorethane (jig/kg)
                               hour 4
0.0    20.0    40.0    60.0    80.0    100.0

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      Forested Areas and Estimated 3 Month Total Ozone Exposure (1988)
  Ozone Exposure,
  Total (ppm-hrs)

         •   o
             1-20
            2CMO
            40-60
            >60
         E3 Forested Areas
            (Generally greater than 30% cover)
Ozone exposure to
forested areas
estimated for a
three month period
in 1988.
   program, which assesses impacts of ozone on natural re-
   sources, has examined 11 ecologically and economically
   important tree species in studies at sites across the country.
   This research provided significant information on the effects of
   ozone on trees for the Agency's  1995 Draft Criteria Document.
   Quantification of ozone effects on forests is needed to address
   the requirements of the  Clean Air Act.

   For the first time, important exposure data for performing
   ecological risk assessments has been summarized. Scientists
   with EPA's Office of Health and Environmental Assessment in
   Washington, D.C., developed the Wildlife Exposure Factors
   Handbook, a compendium of data on 30 species of birds,
   mammals, amphibians,  and reptiles. The data, which includes
   body weights, ingestion rates, inhalation rates, diets, and home
   range sizes, is combined with toxicity data to conduct ecologi-
   cal risk assessments at contaminated waste sites or to support
   chemical criteria for wildlife.

Risk Assessment Landmarks
   Risk assessment is a constantly evolving science. ORD is in
   the forefront of the research that seeks to reduce uncertainties
   of risk assessment by continually refining the methods and
                 10

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data which support Agency-wide risk assessments and guide-
lines for conducting risk assessments. The guidelines, which
are peer-reviewed by the wider scientific community, represent
ORD's contributions to the "state of the science" of risk
assessment. In FY1994, ORD contributed to the following :

Guidelines for Reproductive Toxicity Risk Assessment were
proposed and reviewed by EPA's Science Advisory Board.
These guidelines represent the first effort by any federal or
state agency, nation, or international organization to provide
guidance for interpreting, analyzing, and using data from
studies on a variety of male and female reproductive effects.
Cancer Risk Assessment Guidelines were revised and peer
reviewed at a public workshop. Last published in 1986, the
guidelines have been revised to incorporate the latest scientific
thinking in the field and to build upon the experience gained in
using the previous guidelines for the last eight years.  These
guidelines will be ready for public comment in FY1995.

With the 1992 Framework for Ecological Risk Assessment,
ORD began developing Agency-wide guidance for improving
the consistency and quality of ecological risk assessments. In
FY1994, ORD published^ Review of Ecological Case Studies
from a Risk Assessment Perspective Volume 2. This report
contains 17 peer reviewed case studies that evaluate ecological
assessments of Agency activities such as pesticides and Super-
fund assessments and nine issue papers that explore topics of
the ecological risk
assessment process
ranging from
model develop-
ment and
characterization of
effects to risk
integration meth-
ods and ecological
significance.
Together, the case
studies and issue
papers will help
provide the  scien-
tific basis for the
development of the
first Agency-wide
ecological risk
assessment guide-
line.
An EPA helicopter crew
samples water for acidity.
                                                          11

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   Risk Management
      Research and development in the risk management area covers
   prevention, reduction, and remediation activities that ORD con-
   ducts in its own laboratories and through agreements with public
   and private sector partners. The accomplishments for FY1994
   reflect a wide range of activity.

   U.S. Navy Considers CFC Replacements
   Identified by EPA
      EPA's Air and Energy Engineering Research Laboratory in
      RTF, North Carolina, is conducting research to find chemicals
      that can be used to replace ozone-depleting refrigerants,
      chlorofluorocarbons (CFCs). Two of the replacements identi-
      fied by the laboratory are being considered by the Navy for use
      in shipboard chillers. The  substitute could save $500 million in
      retrofit and replacement costs and help timely phaseout of the
      CFC currently used. The Navy will make its final decision on a
      replacement chemical in 1995.

   Particulate Matter Five-Year Research Strategy
      ORD completed a strategy for research to support the Agency's
      court-ordered deadline to review the Particulate Matter Na-
      tional Ambient Air Quality Standard (NAAQS). The strategy
      outlines the policy and scientific issues and the research
      questions that must be addressed and it ranks the needed
      research. EPA program  offices, industry, academia, environ-
      mental groups, other federal agencies, and states have had an
      opportunity to review and comment on this document. This
      document will guide  EPA's research efforts for the next five
      years.

   NARSTO Focuses Tropospheric  Ozone Research
      In response to the 1990 Clean Air Act Amendments and a 1991
      National Academy of Sciences report calling for a national
      program of tropospheric ozone research, ORD scientists and
      stakeholders in the public  and private sectors developed the
      North American Research Strategy for Tropospheric Ozone
      (NARSTO). The strategy established agreement to focus
      research on understanding the sources of emissions that effect
      the ozone level in the air we breathe and to coordinate research
      activities throughout North America. Coordination is important
      because there has been duplication of research across different
      regions of the country with serious nonattainment problems.
      These regions have had to reinvent measures, modeling, and
      emission categories.  A  charter outlining activities and partici-
12

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    pants was signed in February 1995 by EPA, other federal
    agencies, states, universities, and major industry organizations.

New Process Prevents Dioxin Formation During
Waste Combustion
    With pilot-scale testing completed, ORD is ready to identify a
    commercial partner to
    demonstrate its
    patented process for
    preventing the forma-
    tion of dioxin and
    furan from burning
    waste. Approximately
    75% of the 250
    existing incinerators
    covered by EPA's
    regulations could be
    retrofitted cheaply
    with the technology
    called Sorbent
    Injection for Chlori-
    nated Organic Re-
    moval/Elimination
    (SICORE). Efforts are
    underway to license
    the technology to a
    commercial partner interested in a demonstration project.

Water Weeds Clean  Munitions Contamination
    An experimental process developed by scientists at EPA's
    Environmental Research Laboratory in Athens, Georgia, uses
    common pond weeds to break down TNT,  chlorinated solvents,
    and several other chemicals found at old munitions sites. The
    plants, which include stonewort, hornwort, and parrot feather,
    contain enzymes that initiate a chain reaction that breaks down
    the TNT molecule into biodegradable material. An EPA patent
    of the process is pending and field testing is scheduled for the
    spring at a closed Army munitions plant.

Technical Support for Agency Activities
    ORD's research program supports the Agency's activities and
    provides site-specific technical assistance and technology
    transfer to state and local governments. For example, in FY94
    scientists at EPA's laboratory in Ada, Oklahoma, and the
    Exposure Assessment Group in Washington, B.C., provided
    technical support and review of the  Soil Screening Level
                              The SICORE process prevents
                              dioxin from forming by
                              reducing the amount ofHCl
                              available to form dioxin.
   Sorbent Injection for Chlorinated Organic
        Removal/Elimination (SICORE)
MUNICIPAL WASTE COMBUSTOR APPLICATION
              Temperature through System
                                              Stack
                                       Sorbent
                                       Injection Zone

                                       Dioxin/Furan
                                       Formation Zone
                                                           13

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      Guidance being developed by the Office of Solid Waste and
      Emergency Response. The guidance is a tool for site managers
      to streamline the Remedial Investigation/Feasibility Study
      process for Superfund sites.

      ORD's Technical Support Center (TSC) in Ada, Oklahoma,
      provides the latest scientific information about the movement
      and fate of contaminants in the soil and groundwater at hazard-
      ous waste sites. TSC scientists and engineers advise on a range
      of questions about site characterizations, treatability studies,
      remediation designs, and cleanup levels. By the end of
      FY1994, TSC staff have provided assistance for almost 700
      requests at over 400 Superfund and RCRA sites across the
      country. The data gathered through the years in the course of
      providing technical assistance have become a tremendous
      information resource for site cleanup managers looking for
      background on contaminants and remediation strategies that
      work.

      Scientists at EPA's Environmental Monitoring Laboratory in
      Cincinnati, Ohio, developed a more sensitive method for
      measuring sewage contamination of drinking water. They also
      completed a survey of groundwater systems for enteric viruses
      that provides an indication of the nature and magnitude of viral
      contamination of vulnerable drinking water wells. EPA lacked
      virus occurrence data to support a regulatory level for virus
      inactivation in public groundwater systems.

      EPA's Center for Environmental Research Information (CERI)
      in Cincinnati, Ohio, published a document for small communi-
      ties on adapting alternative treatment technologies for smaller
      systems. Small communities are participating in ORD studies
      to evaluate treatment technologies. Results to date indicate that
      small systems can upgrade drinking water quality at a reason-
      able cost. CERI also published a handbook on groundwater
      and wellhead protection for delineating the boundaries of a
      wellhead protection area, identifying and evaluating potential
      contaminants and wellhead management options.

   Innovations for Solving Environmental Problems
      ORD develops and evaluates promising pollution prevention,
      pollution control and  remediation technologies, as well as the
      monitoring devices and techniques that validate the results of
      technologies. In addition to in-house research, there are a
      number of programs that harness the resources and expertise of
      scientists and researchers in academia, other federal research
14

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organizations and the
private sector.
One such program, the
Superfund Innovative
Technology Evaluation
(SITE) Program, begins
its tenth year with 72
technologies in the
developmental program
and 115 technologies in
the demonstration
program. Through 1994,
69 field demonstrations
and 38 developmental
projects have been
conducted. Many
developers completing
SITE projects credit their participation in SITE as integral to
the success of their companies. A recent assessment of site
remediation costs by four EPA regional offices shows that
using SITE technology saved $358 million over the projected
costs of conventional remediation.

Since  1982, the  Small Business Innovative Research (SBIR)
Program has funded research in EPA program areas that could
lead to significant opportunities and public benefits if the
research is successful. Examples of success stories include:

National Recovery Technologies, Inc., developed a technology
for sorting PVC plastics from recycle collections. NRT has
grown from three people in 1981 to 30 in 1994.

RMC Group produced a pallet made of 100 percent recycled
plastics from a range of resin types, including 50 percent post-
consumer plastics.  Currently they manufacture 400 pallets per
week and expect to make 2000 per week by July 1995.

With 11 new Cooperative Research and Development Agree-
ments (CRADAs) and 5 new licensing agreements in FY 1994,
EPA has a total of 60 Federal Technology Transfer Act (FTTA)
agreements and licensing agreements. Noteworthy agreements
signed in FY1994 include:

The "Lasagna CRADA," an agreement with Monsanto,
DuPont, and General Electric to develop and  field test new
technologies for treating dense, clay-like soil at hazardous
waste sites. Dubbed the "lasagna" process, it  uses an electric
Approximately 16 tons of
contaminated soil were treated
at this SITE demonstration
project.
                                                         15

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          Horizontal Configuration
    Ground surface
Borehole
   I I
               ;^T   Tr
 Applied Electrical^—-	u—
                             Granular electrode
                 Treatment
                  zones
     Potential
                                 ~?*- Contaminated
                                 •—-^     soil
                             Granular electrode
                                       Vertical Configuration
                                                                    Ground surface
                                                                   electro-
                                       Y
                                                                           osmotic
                                                                           flow  *"
                                                           Treatment
                                                            zones
                                                      Contaminated
                                                          soil
                                                           Note: Electro-osmotic flow is reversed
                                                           upon switching polarity.
Horizontal (a) and vertical (b)
configurations of the
"Lasagna " hazardous waste
treatment process. Flow
reversal allows multiple passes
of the contaminants through
the treatment zones.
                  field to draw waste into layered areas called treatment zones.
                  Once layered, the two wastes can be treated completely in
                  place. This process promises to be more cost-effective than
                  traditional cleanup methods.

                  Two licensing agreements with ETG Environmental, Inc., and
                  Soil Tech ATP Systems, Inc., are marketing an EPA patented
                  technology for cleaning up chlorinated chemical wastes. The
                  technology, base catalyzed decomposition, involves adding a
                  common base such as baking soda to the contaminated mate-
                  rial and then heating the mixture. The process turns the toxic
                  contaminants into non-hazardous materials.
                                 16

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