United States             730L97001
          Environmental Protection         March 1997
          Agency	
          Office of Pesticide Programs	
V>EPA   The Federal Insecticide,
          Fungicide, and Rodenticide
          Act (FIFRA)  and Federal
          Food, Drug, and Cosmetic
          Act (FFDCA) As Amended
          by the Food Quality
          Protection Act (FQPA) of
          August 3,1996

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                            CONTENTS


                                                                          Page

            FEDERAL INSECTICIDE, FUNGICIDE, AND RODENTICIDE ACT

 1. Short title and table of contents	     3
 2. Definitions 	     7
 3. Registration of pesticides 	    16
 4. Reregistration of registered pesticides	    36
 5. Experimental use permits 	    58
 6. Administrative review; suspension  	    59
 7. Registration of establishments 	    65
 8. Books and records	    66
 9. Inspection of establishments, etc	    67
10. Protection of trade secrets and other information  	    68
11. Use of restricted use pesticides; applicators	    71
12. Unlawful acts 	    73
13. Stop sale, use, removal, and seizure 	    75
14. Penalties 	    77
15. Indemnities 	    78
16. Administrative procedure; judicial review	    81
17. Imports and exports 	    81
18. Exemption of Federal and State agencies  	    82
19. Storage, disposal, transportation, and recall	    83
20. Research and monitoring 	    88
21. Solicitation of comments; notice of public hearings 	    88
22. Delegation and cooperation	    88
23. State cooperation, aid, and training	    89
24. Authority of States 	    89
25. Authority of Administrator  	    90
26. State primary enforcement responsibility  	    94
27. Failure  by  the  State to  assure  enforcement  of State pesticide  use
  regulations 	    95
28. Identification of  pests;   cooperation with  Department  of Agriculture's
  program	    96
29. Annual report	    96
30. Minimum requirements  for  training  of maintenance  applicators  and
  service technicians 	    97
31. Environmental Protection Agency minor use program 	    97
32. Department of Agriculture minor use program 	    97
33. Severability 	    98
34. Authorization for appropriations 	    98

        FEDERAL FOOD, DRUG, AND  COSMETIC ACT (TITLES i THROUGH rvo

Chapter I—Short title 	  101
Chapter II—Definitions	  102
Chapter III—Prohibited acts and penalties  	  110
Chapter IV—Food 	  135

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FEDERAL INSECTICIDE, FUNGICIDE, AND RODENTICIDE
                      ACT

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FEDERAL INSECTICIDE, FUNGICIDE, AND RODENTICIDE
                                 ACT

          (References [ ] in brackets are to title 7, United States Code)

                    (ACT OF JUNE 25, 1947; CHAPTER 125)


 AN ACT To regulate the marketing of economic poisons and devices, and for other
                                purposes.

    Be it enacted by  the Senate and House of Representatives of the
United States of America in Congress assembled,

SECTION 1. [prec. 121] SHORT TITLE AND TABLE OF CONTENTS.
    (a) SHORT TITLE.—This Act may be cited as the "Federal Insec-
ticide, Fungicide, and Rodenticide Act".
    (b) TABLE OF CONTENTS.—x

Section 1. Short title and table of contents.
    (a) Short title.
    (b) Table of contents.
Sec. 2. Definitions.
    (a) Active ingredient.
    (b) Administrator.
    (c) Adulterated.
    (d) Animal.
    (e) Certified applicator, etc.
       (1) Certified applicator.
       (2) Private applicator.
       (3) Commercial applicator.
       (4) Under the direct supervision of a certified applicator.
    (f) Defoliant.
    (g) Desiccant.
    (h) Device.
    (i) District court.
    (j) Environment.
    (k) Fungus.
    (1) Imminent hazard.
    (m) Inert ingredient.
    (n) Ingredient statement.
    (o) Insect.
    (p) Label and labeling.
       (1) Label.
       (2) Labeling.
    (q) Misbranded.
    (r) Nematode.
    (s) Person.
    (t) Pest.
    (u) Pesticide.
    (v) Plant regulator.
    (w) Producer and produce.
    (x) Protect health and the environment.
    (y) Registrant.
    (z) Registration.
    (aa) State.
  1 So in original. The table of contents does not correspond to the contents of the Act. Public
Law 104-170 did not make conforming amendments to the table of contents.

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Sec. 1	FIFRA	4


    (bb) Unreasonable adverse effects on the environment.
    (cc) Weed.
    (dd) Establishment.
    (ee) To use any registered pesticide in a manner inconsistent with its labeling.
    (ff) Outstanding data requirement.
    (gg) To distribute or sell.
Sec. 3. Registration of pesticides.
    (a) Requirement of registration.
    (b) Exemptions.
    (c) Procedure for registration.
        (1) Statement required.
        (2) Data in support of registration.
        (3) Time for acting with respect to application.
        (4) Notice of application.
        (5) Approval of registration.
        (6) Denial of registration.
        (7) Registration  under special circumstances.
        (8) Interim administrative review.
    (d) Classification of pesticides.
        (1) Classification for general use, restricted use, or both.
        (2) Change in classification.
        (3) Change in classification from restricted use to general use.
    (e) Products with same formulation and claims.
    (f) Miscellaneous.
        (1) Effect of change of labeling or formulation.
        (2) Registration  not a defense.
        (3) Authority to  consult other Federal agencies.
Sec. 4. Reregistration of registered pesticides.
    (a) General rule.
    (b) Reregistration phases.
    (c) Phase one.
        (1) Priority for reregistration.
        (2) Reregistration lists.
        (3) Judicial review.
        (4) Notice to registrants.
    (d) Phase two.
        (1) In general.
        (2) Notice of intent to seek or not to seek reregistration.
        (3) Missing or inadequate data.
        (4) Time periods.
        (5) Cancellation and removal.
        (6) Suspensions  and penalties.
    (e) Phase three.
        (1) Information about studies.
        (2) Time periods.
        (3) Cancellation.
        (4) Guidelines.
        (5) Monitoring.
    (f) Phase four.
        (1) Independent review and identification of outstanding data requirements.
        (2) Time periods.
        (3) Suspensions  and penalties.
    (g) Phase five.
        (l)Data review.
        (2) Reregistration and other actions.
    (h) Compensation of data submitter.
    (i) Fees.
        (1) Initial fee for food or feed use pesticide active ingredients.
        (2) Final fee for  food or feed use pesticide active ingredients.
        (3) Fees for other pesticide active ingredients.
        (4) Reduction or waiver of fees for minor use and other pesticides.
        (5) Maintenance fee.
        (6) Other fees.
        (7) Apportionment.
    (j) Exemption of certain registrants.
    (k) Reregistration and expedited processing fund.
        (1) Establishment.
        (2) Source and use.

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5	FIFRA	Sec. 1


        (3) Expedited processing of similar applications.
        (4) Unused funds.
        (5) Accounting.
    (1) Judicial review.
Sec. 5. Experimental use permits.
    (a) Issuance.
    (b) Temporary tolerance level.
    (c) Use under permit.
    (d) Studies.
    (e) Revocation.
    (f) State issuance of permits.
    (g) Exemption for agricultural research agencies.
Sec. 6. Administrative review; suspension.
    (a) Cancellation after five years.
        (1) Procedure.
        (2) Information.
    (b) Cancellation and change in classification or labels.
    (c) Suspension.
        (1) Order.
        (2) Expedite hearing.
        (3) Emergency order.
        (4) Judicial review.
    (d) Public hearings and scientific review.
    (e) Conditional registration.
    (f) General provisions.
        (1) Voluntary cancellation.
        (2) Publication of notice.
        (3)  Transfer of registration  of pesticides registered for minor agricultural
    uses.
    (g) Notice for stored pesticides with canceled or suspended registrations.
        (1) In general.
        (2) Copies.
    (h) Judicial review.
Sec. 7. Registration of establishments.
    (a) Requirements.
    (b) Registration.
    (c) Information required.
    (d) Confidential records and information.
Sec. 8. Records.
    (a) Requirement.
    (b) Inspection.
Sec. 9. Inspection of establishments, etc.
    (a) In general.
    (b) Warrants.
    (c) Enforcement.
        (1) Certification of facts to Attorney General.
        (2) Notice not required.
        (3) Warning notices.
Sec. 10. Protection of trade secrets and other information.
    (a) In general.
    (b) Disclosure.
    (c) Disputes.
    (d) Limitations.
    (e) Disclosure to contractors.
    (f) Penalty for disclosure by Federal employees.
    (g) Disclosure to foreign and multinational pesticide producers.
Sec. 11. Use of restricted  use pesticides; applicators.
    (a) Certification procedure.
        (1) Federal  certification.
        (2) State certification.
    (b) State plans.
    (c) Instruction in integrated pest management techniques.
    (d) In general.
    (e) Separate standards.
Sec. 12. Unlawful acts.
    (a) In general.
    (b) Exemptions.
Sec. 13. Stop sale, use, removal, and seizure.

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Sec. 1	FIFRA	


    (a) Stop sale, etc., orders.
    (b) Seizure.
    (c) Disposition after condemnation.
    (d) Court costs, etc.
Sec. 14. Penalties.
    (a) Civil penalties.
        (1) In general.
        (2) Private applicator.
        (3) Hearing.
        (4) Determination of penalty.
        (5) References to Attorney General.
    (b) Criminal penalties.
        (1) In general.
        (2) Private applicator.
        (3) Disclosure of information.
        (4) Acts of officers, agents, etc.
Sec. 15. Indemnities.
    (a) General indemnification.
        (1) In general.
        (2) Exception.
        (3) Report.
        (4) Appropriation.
    (b) Indemnification of end users, dealers, and distributors.
        (1) End users.
        (2) Dealers and distributors.
        (3) Source.
        (4) Administrative settlement.
    (c) Amount of payment.
        (1) In general.
        (2) Special rule.
Sec. 16. Administrative procedure; judicial review.
    (a) District court review.
    (b) Review by Court of Appeals.
    (c) Jurisdiction of district courts.
    (d) Notice of judgments.
Sec. 17. Imports and exports.
    (a) Pesticides and devices intended for export.
    (b) Cancellation notices furnished to foreign governments.
    (c) Importation of pesticides and devices.
    (d) Cooperation in international efforts.
    (e) Regulations.
Sec. 18. Exemption of Federal and State agencies.
Sec. 19. Storage, disposal, transportation, and recall.
    (a) Storage, disposal, and transportation.
        (1) Data requirements and registration of pesticides.
        (2) Pesticides.
        (3) Containers, rinsates, and other materials.
    (b) Recalls.
        (1) In general.
        (2) Voluntary recall.
        (3) Mandatory recall.
        (4) Recall procedure.
        (5) Contents of recall plan.
        (6) Requirements or procedures.
    (c) Storage costs.
        (1) Submission of plan.
        (2) Reimbursement.
    (d) Administration of storage, disposal, transportation, and recall programs.
        (1) Voluntary agreements.
        (2) Rule and regulation review.
        (3) Limitations.
        (4) Seizure and penalties.
    (e) Container design.
        (1) Procedures.
        (2) Compliance.
    (f) Pesticide residue removal.
        (1) Procedures.
        (2) Compliance.

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7	FIFRA	Sec. 2


       (3) Solid Waste Disposal Act.
    (g) Pesticide container study.
       (1) Study.
       (2) Report.
    (h) Relationship to Solid Waste Disposal Act.
Sec. 20. Research and monitoring.
    (a) Research.
    (b) National monitoring plan.
    (c) Monitoring.
Sec. 21. Solicitation of comments; notice of public hearings.
    (a) Secretary of Agriculture.
    (b) Views.
    (c) Notice.
Sec. 22. Delegation and cooperation.
    (a) Delegation.
    (b) Cooperation.
Sec. 23. State cooperation, aid, and training.
    (a) Cooperative agreements.
    (b) Contracts for training.
    (c) Information and education.
Sec. 24. Authority of States.
    (a) In general.
    (b) Uniformity.
    (c) Additional uses.
Sec. 25. Authority of Administrator.
    (a) In General.
       (1) Regulations.
       (2) Procedure.
       (3) Congressional committees.
       (4) Congressional review of regulations.
    (b) Exemption of pesticides.
    (c) Other authority.
    (d) Scientific advisory panel.
Sec. 26. State primary enforcement responsibility.
    (a) In general.
    (b) Special rules.
    (c) Administrator.
Sec. 27. Failure  by  the  State  to  assure  enforcement of State  pesticide  use
           regulations.
    (a) Referral.
    (b) Notice.
    (c) Construction.
Sec. 28. Identification of pests; cooperation  with Department of Agriculture's
           program.
    (a) In general.
    (b) Pest control availability.
       (1) In general.
       (2) Report.
    (c) Integrated pest management.
Sec. 29. Annual report.
Sec. 30. Severability.
Sec. 31. Authorization for appropriations.

SEC. 2. [136] DEFINITIONS.
    For purposes of this Act—
    (a) ACTIVE INGREDIENT.—The term "active ingredient" means—
         (1) in the case of a pesticide other than a plant regulator,
    defoliant, desiccant, or nitrogen stabilizer, an ingredient which
    will prevent, destroy, repel, or mitigate any pest;
         (2) in the case of a plant regulator,  an ingredient which,
    through physiological action, will accelerate  or retard  the rate
    of growth or rate of maturation or otherwise alter the behavior
    of ornamental or crop plants or the product thereof;
         (3) in the  case  of a  defoliant, an ingredient  which will
    cause  the leaves or foliage to drop from a plant;

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Sec. 2	FIFRA	8

        (4) in the case of a desiccant, an ingredient which will arti-
    ficially accelerate the drying of plant tissue; and
        (5) in the case of a nitrogen  stabilizer, an ingredient which
    will   prevent   or   hinder   the  process   of  nitrification,
    denitrification,  ammonia  volatilization,  or  urease  production
    through action affecting soil bacteria.
    (b) ADMINISTRATOR.—The  term "Administrator" means the Ad-
ministrator of the Environmental Protection Agency.
    (c) ADULTERATED.—The term "adulterated" applies to any pes-
ticide if—
        (1) its strength or purity falls below the professed standard
    of quality as expressed on its labeling under which it is  sold;
        (2) any substance has been substituted  wholly or in part
    for the pesticide; or
        (3)  any valuable  constituent of the pesticide  has  been
    wholly or in part abstracted.
    (d) ANIMAL.—The term "animal" means all  vertebrate and in-
vertebrate species,  including  but not limited to man and other
mammals, birds, fish, and shellfish.
    (e) CERTIFIED APPLICATOR, ETC.—
        (1) CERTIFIED APPLICATOR.—The term "certified applicator"
    means any individual who is certified under section 11 as au-
    thorized  to use or supervise the use of any pesticide which  is
    classified for restricted use.  Any applicator  who holds or ap-
    plies registered  pesticides, or uses  dilutions of registered pes-
    ticides consistent with subsection (ee), only to provide a service
    of controlling pests without delivering any unapplied pesticide
    to any person so served is not deemed to be a seller or distribu-
    tor of pesticides  under this Act.
        (2)  PRIVATE  APPLICATOR.—The term "private  applicator"
    means a certified applicator who uses or supervises the use  of
    any pesticide which is classified for restricted use for purposes
    of producing any agricultural commodity on property owned  or
    rented by the applicator or the applicator's employer or (if ap-
    plied  without compensation other than trading of personal
    services between producers of agricultural commodities) on the
    property of another person.
        (3) COMMERCIAL  APPLICATOR.—The  term "commercial ap-
    plicator" means  an applicator (whether  or not the applicator is
    a private applicator with respect to some uses) who uses or su-
    pervises  the use of any  pesticide  which is classified for re-
    stricted use for  any purpose or  on any  property other than  as
    provided by paragraph (2).
        (4) UNDER THE DIRECT SUPERVISION OF A CERTIFIED APPLI-
    CATOR.—Unless  otherwise prescribed by its labeling, a  pes-
    ticide shall be considered  to be applied  under the direct super-
    vision of a certified  applicator if it is applied by a competent
    person acting under the instructions  and control of a certified
    applicator  who is available if and  when needed, even though
    such  certified applicator is  not  physically present at the time
    and place the pesticide is  applied.
    (f) DEFOLIANT.—The term "defoliant" means any substance  or
mixture of substances intended for causing the leaves or  foliage  to
drop from a plant, with or without causing abscission.

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9	FIFRA	Sec. 2

    (g) DESICCANT.—The term "desiccant" means any substance or
mixture of substances intended for artificially accelerating the dry-
ing of plant tissue.
    (h) DEVICE.—The term "device" means any instrument or con-
trivance (other than a firearm) which is intended for trapping, de-
stroying, repelling, or mitigating any pest or any other form of
plant or animal life (other than man and other than bacteria, virus,
or other microorganism on or in living man  or other living ani-
mals); but not including equipment used for the application of pes-
ticides when sold separately therefrom.
    (i) DISTRICT COURT.—The term "district court"  means a United
States district court, the District Court of Guam, the District Court
of the Virgin Islands, and the highest court of American Samoa.
    (j) ENVIRONMENT.—The term "environment"  includes water,
air, land, and all plants and man and other animals living therein,
and the interrelationships which exist among these.
    (k) FUNGUS.—The term "fungus" means any  non-chlorophyll-
bearing thallophyte (that is, any non-chlorophyll-bearing plant of a
lower  order than mosses  and liverworts),  as for example,  rust,
smut, mildew, mold, yeast, and bacteria, except those on or in liv-
ing man or other animals and those on or in  processed food, bev-
erages, or pharmaceuticals.
    (1) IMMINENT HAZARD.—The term "imminent hazard" means a
situation which exists when the continued  use of a  pesticide during
the time required for cancellation proceeding would be likely to re-
sult in unreasonable adverse effects on the environment or will in-
volve unreasonable hazard to the survival  of a species declared en-
dangered by the  Secretary of the Interior under Public Law 91-
135.
    (m) INERT INGREDIENT.—The term "inert ingredient" means an
ingredient which is not active.
    (n) INGREDIENT STATEMENT.—The term "ingredient statement"
means a statement which contains—
       (1) the name and percentage of each active ingredient, and
    the total percentage  of all inert ingredients, in  the pesticide;
    and
       (2) if the pesticide contains  arsenic in any form, a state-
    ment of the percentages of total and water soluble arsenic, cal-
    culated as elementary arsenic.
    (o) INSECT.—The term "insect" means any of the  numerous
small invertebrate animals generally having the body more or less
obviously segmented, for the most  part  belonging to the  class
insecta, comprising six-legged, usually winged  forms, as for exam-
ple,  beetles,  bugs,  bees,  flies, and to   other allied classes  of
arthropods  whose members are wingless  and  usually have more
than six legs, as for example, spiders, mites, ticks,  centipedes, and
wood lice.
    (p) LABEL AND LABELING.—
       (1) LABEL.—The term "label" means the written, printed,
    or graphic matter on, or attached to, the pesticide or device or
    any of its containers or wrappers.
       (2) LABELING.—The term "labeling" means all labels and
    all other written, printed, or graphic matter—

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Sec. 2	FIFRA	10

            (A) accompanying the pesticide or device at any time;
        or
            (B) to which reference is made on the label or in lit-
        erature  accompanying the pesticide or device, except to
        current official publications of the Environmental Protec-
        tion Agency, the United States Departments of Agriculture
        and Interior, the Department of Health and Human Serv-
        ices, State experiment stations, State agricultural colleges,
        and other similar Federal or State institutions or agencies
        authorized by  law to conduct research in  the field of pes-
        ticides.
    (q) MISBRANDED.—
        (1) A pesticide is misbranded if—
            (A) its labeling bears any statement, design, or graphic
        representation relative thereto or to its ingredients which
        is false or misleading in any particular;
            (B) it is contained in a package or  other container or
        wrapping which does not conform to the standards estab-
        lished by the Administrator pursuant to section 25(c)(3);
            (C) it is an imitation of, or is offered for sale under the
        name of,  another pesticide;
            (D) its label does not bear the registration number as-
        signed under section 7  to each  establishment in which it
        was produced;
            (E) any word, statement, or other  information required
        by or under authority of this Act to appear on the label or
        labeling is not prominently  placed thereon with such con-
        spicuousness (as compared with other words, statements,
        designs,  or  graphic matter in  the labeling) and in  such
        terms as to render it likely to be read and understood by
        the ordinary individual under customary conditions of pur-
        chase and use;
            (F) the labeling accompanying it  does not  contain di-
        rections for use which are necessary for effecting the pur-
        pose for  which the product is  intended  and if complied
        with, together with any requirements imposed under sec-
        tion 3(d)  of this Act, are adequate to protect health and the
        environment;
            (G)  the label  does  not  contain a warning or caution
        statement which may be necessary and if complied with,
        together  with any requirements imposed under  section 3(d)
        of this Act, is adequate to protect health and the environ-
        ment; or
            (H) in the case of a pesticide not  registered in accord-
        ance with section 3 of this Act and intended for export, the
        label does not contain, in words prominently placed there-
        on  with  such  conspicuousness  (as compared  with other
        words, statements, designs, or graphic matter in the label-
        ing) as to render it likely to be noted  by the ordinary indi-
        vidual under  customary conditions of purchase and use,
        the following: "Not Registered for Use in the United States
        of America".
        (2) A pesticide is misbranded if—

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11	FIFRA	Sec. 2

            (A) the label does not bear an ingredient statement on
        that part of the immediate  container (and on the outside
        container or wrapper of the retail package, if there be one,
        through which the ingredient statement on the immediate
        container cannot be clearly read) which is presented or dis-
        played under customary conditions  of purchase,  except
        that a pesticide is not  misbranded under this  subpara-
        graph if—
                (i) the size or form of the immediate container, or
            the outside container or wrapper of the retail package,
            makes it impracticable  to place the ingredient  state-
            ment on the  part  which is presented  or displayed
            under customary conditions of purchase; and
                (ii) the ingredient statement appears prominently
            on another part of the immediate container, or outside
            container or wrapper, permitted by the Administrator;
            (B) the  labeling does not contain a statement of the
        use classification under which the product is registered;
            (C) there is not affixed to its container, and to the out-
        side container or wrapper of the  retail package, if there be
        one, through which the required information  on the imme-
        diate container cannot be clearly read, a label bearing—
                (i) the name and address of the producer, reg-
            istrant, or person for whom produced;
                (ii) the name, brand, or trademark under which
            the pesticide is sold;
                (iii) the net weight or measure of the content, ex-
            cept  that the Administrator may permit  reasonable
            variations; and
                (iv) when required by regulation of the  Adminis-
            trator to effectuate  the  purposes  of this Act, the reg-
            istration number assigned to the pesticide under this
            Act, and the use classification; and
            (D) the pesticide contains any substance or substances
        in quantities highly toxic to man,  unless the  label shall
        bear, in  addition  to any other matter required by this
        Act—
                (i) the skull and crossbones;
                (ii) the  word "poison" prominently  in red on  a
            background of distinctly contrasting color; and
               (iii) a statement of a practical treatment (first aid
            or otherwise) in case of poisoning by the pesticide.
    (r) NEMATODE.—The term "nematode" means invertebrate ani-
mals of the phylum nemathelminth.es and class nematoda, that is,
unsegmented round worms with elongated, fusiform, or saclike bod-
ies covered with cuticle, and inhabiting soil, water, plants, or plant
parts; may also be called nemas or eelworms.
    (s) PERSON.—The term "person" means any individual, partner-
ship, association,  corporation, or any  organized group of persons
whether incorporated or not.
    (t) PEST.—The term "pest" means (1) any insect, rodent, nema-
tode, fungus, weed, or (2) any other form of terrestrial or aquatic
plant or animal life or virus, bacteria, or  other micro-organism (ex-
cept viruses, bacteria, or other micro-organisms on or in living man

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Sec. 2	FIFRA	12

or other living animals) which the Administrator declares to be a
pest under section 25(c)(l).
    (u) PESTICIDE.—The term "pesticide" means (1) any substance
or mixture of substances intended for preventing, destroying, repel-
ling, or mitigating any pest, (2) any substance or mixture of sub-
stances intended for  use  as a plant regulator, defoliant, or des-
iccant, and (3) any nitrogen stabilizer, except that the term "pes-
ticide" shall not include  any article that is a "new animal drug"
within the meaning of section 201(w) of the Federal  Food,  Drug,
and Cosmetic Act (21 U.S.C. 321(w)), that has been determined by
the Secretary of Health and Human Services not to be a new ani-
mal drug by a regulation establishing conditions of use for the arti-
cle, or that is an animal feed within the meaning of section 201(x)
of such Act (21 U.S.C. 321(x)) bearing or containing a new animal
drug.  The term  "pesticide"  does  not  include  liquid  chemical
sterilant products (including any sterilant or subordinate disinfect-
ant claims on such products) for use on a critical or  semi-critical
device, as defined in section 201  of the Federal Food, Drug, and
Cosmetic Act (21 U.S.C.  321). For purposes of the preceding sen-
tence, the term "critical device" includes  any device which is intro-
duced directly into the human body, either into or in contact with
the bloodstream or normally sterile areas of the body and the term
"semi-critical device" includes any  device which contacts intact mu-
cous membranes but which  does not ordinarily penetrate the blood
barrier or otherwise enter normally sterile areas  of the  body.
    (v) PLANT REGULATOR.—The term "plant regulator" means any
substance or mixture of substances intended, through physiological
action, for accelerating or retarding the rate of growth or  rate of
maturation, or for otherwise altering the behavior of plants or the
produce thereof, but shall not include substances to the extent that
they are intended as plant nutrients, trace elements, nutritional
chemicals, plant inoculants, and soil amendments. Also, the term
"plant regulator" shall not  be required to include any  of such of
those  nutrient mixtures  or soil  amendments  as are  commonly
known as vitamin-hormone horticultural products, intended for im-
provement,  maintenance,  survival,  health, and propagation  of
plants, and as  are not for pest destruction and  are nontoxic, non-
poisonous in the undiluted packaged  concentration.
    (w) PRODUCER AND PRODUCE.—The term "producer" means the
person who manufacturers, prepares, compounds, propagates, or
processes  any pesticide or device or  active ingredient  used  in pro-
ducing a pesticide. The term "produce" means to manufacture, pre-
pare, compound, propagate,  or process any pesticide or  device or  ac-
tive ingredient used in producing a pesticide. The dilution by indi-
viduals of formulated pesticides for their own use and according to
the directions on registered labels shall not of itself result in such
individuals being included  in the definition of  "producer" for the
purposes of this Act.
    (x) PROTECT HEALTH AND THE  ENVIRONMENT.—The terms "pro-
tect health and the environment" and "protection of health and the
environment"  mean protection against any unreasonable adverse
effects on the environment.
    (y)  REGISTRANT.—The term "registrant" means a person who
has registered any pesticide pursuant to the provisions of this Act.

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13	FIFRA	Sec. 2

    (z) REGISTRATION.—The term "registration" includes reregistra-
tion.
    (aa) STATE.—The term "State" means a  State, the District of
Columbia,  the Commonwealth of Puerto Rico, the Virgin Islands,
Guam,  the Trust Territory of the Pacific Islands, and American
Samoa.
    (bb) UNREASONABLE  ADVERSE  EFFECTS ON THE  ENVIRON-
MENT.—The term "unreasonable  adverse effects on  the environ-
ment" means (1) any unreasonable risk to man or the environment,
taking into account the economic, social, and environmental costs
and benefits of the use of any pesticide, or (2) a human dietary risk
from residues that result from a use of a pesticide in or on any food
inconsistent with the standard under section 408 of the Federal
Food, Drug, and Cosmetic Act (21 U.S.C. 346a)./l/ The Adminis-
trator shall consider the risks and benefits  of public health pes-
ticides separate from the risks and benefits of other pesticides. In
weighing any  regulatory action concerning a public health pesticide
under this Act, the Administrator shall weigh any risks of the pes-
ticide against the health risks such as the diseases transmitted by
the vector to be controlled by the pesticide.
    (cc)  WEED.—The term "weed" means any plant  which grows
where not wanted.
    (dd) ESTABLISHMENT.—The term "establishment" means any
place where a pesticide  or device  or  active ingredient used in pro-
ducing a pesticide is produced, or held, for distribution or sale.
    (ee) To USE ANY REGISTERED PESTICIDE  IN A MANNER INCON-
SISTENT WITH ITS LABELING.—The term "to use any registered pes-
ticide in a  manner inconsistent with its labeling" means to use any
registered pesticide in a manner not  permitted by the labeling, ex-
cept that the term shall not include (1) applying a pesticide at any
dosage, concentration, or frequency less than that specified on the
labeling unless the labeling specifically prohibits deviation from the
specified dosage, concentration, or frequency, (2) applying a pes-
ticide against any target pest not specified on the labeling if the
application is  to the crop,  animal, or site specified on the labeling,
unless the  Administrator has  required that the labeling specifically
state that the pesticide may be used  only for  the pests specified on
the labeling after the Administrator has determined  that the  use
of the pesticide against other pests  would  cause an unreasonable
adverse effect on the environment, (3) employing any method of ap-
plication not prohibited  by the labeling unless the labeling specifi-
cally  states that  the product  may be applied only by the methods
specified on the labeling, (4)  mixing  a pesticide  or pesticides with
a fertilizer when such mixture is not prohibited by the labeling,  (5)
any use of a pesticide in conformance with section 5, 18, or 24 of
this Act, or (6) any use of a pesticide in a manner that the Admin-
istrator determines to be consistent with the purposes of this Act.
After March 31, 1979, the term shall not include the  use of a pes-
ticide for agricultural or forestry  purposes  at a  dilution less than
label  dosage unless before or  after that date  the  Administrator is-
sues a regulation or advisory opinion  consistent with the study pro-
  'Sec. 304 of P.L. 104-170 amended sec. 2(bb) (7 U.S.C. 136(bb)) by inserting "(1)" and ", or
(2)" and all that follows through "346a).", without specifying the Act that was being amended.
The amendments were executed to this Act to effectuate the probable intent of Congress.

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Sec. 2	FIFRA	14

vided for in section 27(b) of the Federal Pesticide Act  of  1978,
which regulation or advisory opinion specifically requires the use
of definite amounts of dilution.
    (ff) OUTSTANDING DATA REQUIREMENT.—
        (1)  IN GENERAL.—The  term "outstanding  data  require-
    ment" means a requirement for any study, information, or data
    that is necessary to make a determination under section 3(c)(5)
    and which study, information, or data—
            (A) has not been submitted  to the Administrator;  or
            (B)  if submitted to  the Administrator, the Adminis-
        trator has  determined must be resubmitted because it is
        not  valid, complete, or adequate to make a determination
        under section 3(c)(5) and the regulations and guidelines is-
        sued under such section.
        (2) FACTORS.—In making a determination under paragraph
    (1)(B) respecting a study,  the Administrator shall examine,  at
    a minimum,  relevant protocols,  documentation of the conduct
    and analysis of the study, and the results of the study to deter-
    mine whether the study and the results of the study fulfill the
    data requirement for which the study was  submitted to the
    Administrator.
    (gg) To  DISTRIBUTE OR SELL.—The  term  "to distribute or sell"
means to distribute, sell,  offer for sale, hold for  distribution, hold
for  sale,  hold for shipment, ship, deliver for  shipment,  release for
shipment, or receive and (having so received) deliver or offer to de-
liver. The term does not include the holding or application of reg-
istered pesticides or use  dilutions thereof by any  applicator who
provides a  service of controlling  pests  without  delivering any
unapplied pesticide to any person so served.
    (hh) NITROGEN STABILIZER.—The  term  "nitrogen  stabilizer"
means any  substance or  mixture of substances  intended for pre-
venting or hindering the process of nitrification,  denitrification,
ammonia volatilization, or urease production through action upon
soil bacteria. Such term shall not include—
        (1) dicyandiamide;
        (2) ammonium thiosulfate; or
        (3) any substance or mixture of substances.—
            (A) that was not registered pursuant to section 3 prior
        to January 1, 1992; and
            (B)  that  was in  commercial  agronomic use prior to
        January 1, 1992, with  respect  to  which after January 1,
        1992, the distributor or seller of the substance  or mixture
        has made no specific claim of  prevention or hindering of
        the  process of nitrification,  denitrification,  ammonia vola-
        tilization urease production regardless of the actual use or
        purpose for, or future use or purpose for, the substance or
        mixture.
Statements  made in materials required  to  be submitted to any
State legislative  or regulatory authority, or  required by  such  au-
thority to be included in the labeling or other literature accompany-
ing any such substance or mixture shall not be deemed a specific
claim within the meaning of this subsection.

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 15	FIFRA	Sec. 2

    (jj)1 MAINTENANCE APPLICATOR.—The term "maintenance ap-
 plicator" means any individual who, in the principal course of such
 individual's employment, uses, or supervises the use of, a pesticide
 not classified for restricted use (other than a ready to use consumer
 products pesticide); for the purpose  of providing  structural pest
 control or lawn pest control  including janitors,  general mainte-
 nance personnel, sanitation personnel, and grounds maintenance
 personnel. The term  'maintenance applicator" does not include pri-
 vate applicators  as defined in section 2(e)(2);  individuals who use
 antimicrobial pesticides, sanitizers or disinfectants; individuals em-
 ployed by  Federal, State, and  local governments or any political
 subdivisions thereof, or individuals who use pesticides not classi-
 fied for restricted use in or around then*  homes, boats, sod farms,
 nurseries, greenhouses, or other noncommercial property.
    (kk)  SERVICE TECHNICIAN.—The   term  "service technician"
 means any individual who uses or supervises  the use of pesticides
 (other than  a ready to use consumer products pesticide) for the
 purpose of providing  structural pest control or lawn pest control on
 the property of  another  for a  fee. The term "service technician"
 does not include  individuals who use antimicrobial pesticides, sani-
 tizers  or  disinfectants;  or  who  otherwise  apply  ready to  use
 consumer products pesticides.
    (11) MINOR USE.—The term "minor use" means the use of a pes-
 ticide on an animal,  on a commercial  agricultural crop or site, or
 for the protection of public health where—
        (1) the total United States acreage for the crop is less than
    300,000  acres, as determined by the  Secretary of Agriculture;
    or
        (2) the Administrator, in consultation with the Secretary of
    Agriculture,  determines that, based on information provided by
    an applicant for  registration or a registrant, the use does not
    provide sufficient economic incentive to support the initial reg-
    istration or continuing  registration of a pesticide for such use
    and—
            (A) there are insufficient efficacious alternative reg-
        istered pesticides available for the use;
            (B) the alternatives to the pesticide use pose greater
        risks to the environment or human health;
            (C) the minor use pesticide plays or will play a signifi-
        cant part in managing pest resistance; or
            (D) the minor use pesticide plays or will play a signifi-
        cant part in an integrated pest management program.
The status as a minor use under this subsection shall continue as
long as the Administrator has not determined  that, based on exist-
ing data, such use may cause an unreasonable  adverse effect on the
environment and the  use otherwise qualifies for such status.
    (mm) ANTIMICROBIAL PESTICIDE.—
        (1) IN GENERAL.—The term "antimicrobial pesticide" means
    a pesticide that—
            (A) is intended  to—
  'So in original (as added by sec. 120 of P.L. 104-170). This subsection should probably be
"(ii)" and subsequent subsections should be redesignated accordingly.

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Sec. 3	FIFRA	IB

                (i) disinfect, sanitize, reduce,  or mitigate growth
            or development of microbiological organisms; or
                (ii) protect inanimate objects, industrial processes
            or systems, surfaces, water,  or other  chemical sub-
            stances  from contamination, fouling, or deterioration
            caused by bacteria, viruses, fungi, protozoa,  algae, or
            slime; and
            (B)  in the intended use is exempt from, or otherwise
        not subject to, a tolerance under section 408 of the Federal
        Food, Drug, and Cosmetic Act (21  U.S.C. 346a and 348) or
        a food additive regulation under section 409  of such Act.
        (2)  EXCLUDED  PRODUCTS.—The term  "antimicrobial pes-
    ticide" does not include —
            (A)  a wood preservative or antifouling paint product
        for which a claim of pesticidal activity other than or in ad-
        dition to an activity described in paragraph (1) is made;
            (B)  an agricultural fungicide product; or
            (C)  an aquatic herbicide product.
        (3)  INCLUDED  PRODUCTS.—The term  "antimicrobial pes-
    ticide" does  include any other chemical sterilant product (other
    than  liquid  chemical  sterilant  products exempt under sub-
    section  (u)),  any other  disinfectant product, any other  indus-
    trial microbiocide product, and any other preservative product
    that is not excluded by paragraph (2).
    (nn) PUBLIC HEALTH PESTICIDE.—The  term "public health pes-
ticide" means any minor use pesticide product registered for use
and used  predominantly in public health programs for vector con-
trol or for other recognized health  protection  uses, including the
prevention or mitigation of viruses, bacteria, or other microorga-
nisms (other than viruses, bacteria,  or  other microorganisms on or
in living man or other  living animal) that pose a threat to  public
health.
    (oo) VECTOR.—The term "vector" means  any organism capable
of transmitting the causative agent of human disease or capable of
producing human discomfort or  injury, including mosquitoes, flies,
fleas, cockroaches, or other insects and ticks,  mites, or rats.
SEC. 3. [136a] REGISTRATION OF PESTICIDES.
    (a)  REQUIREMENT OF  REGISTRATION.—Except as  provided  by
this Act, no person in any State may distribute or sell to any per-
son any pesticide that is not registered under this Act. To the ex-
tent necessary to prevent unreasonable adverse effects on the envi-
ronment,  the Administrator may by regulation limit the distribu-
tion, sale, or use in any State of any pesticide that is not registered
under this Act and that is not the subject of an experimental use
permit under section 5 or an emergency exemption under section
18.
    (b) EXEMPTIONS.—A pesticide which is not registered with the
Administrator may be transferred if—
        (1) the transfer is from one registered establishment to an-
    other registered establishment operated  by the same producer
    solely for packaging at the second  establishment or for  use as
    a constituent part of another pesticide produced at the  second
    establishment; or

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17	FIFRA	Sec. 3

        (2) the transfer is pursuant to and in accordance with the
    requirements of an experimental use permit.
    (c) PROCEDURE FOR REGISTRATION.—
        (1) STATEMENT REQUIRED.—Each applicant for registration
    of a pesticide shall  file  with the Administrator a  statement
    which includes—
            (A) the name and address of the applicant and of any
        other person whose name will appear on the labeling;
            (B) the name of the pesticide;
            (C) a complete copy of the labeling of the pesticide, a
        statement of all claims  to be made for it, and any direc-
        tions for its use;
            (D) the complete  formula of the pesticide;
            (E) a request that the pesticide be classified for gen-
        eral use or for restricted use, or for both; and
            (F) except as otherwise provided in paragraph (2)(D),
        if requested by the Administrator, a full description of the
        tests made and the results thereof upon which the claims
        are based, or alternatively a citation to data that  appear
        in  the public literature or that previously had  been sub-
        mitted to  the Administrator and that the Administrator
        may consider in accordance with the following provisions:
                (i) With respect to pesticides containing active in-
            gredients that are initially  registered under this Act
            after the date of enactment of the Federal Pesticide
            Act of 1978,  data submitted to support the application
            for the original registration  of the pesticide, or an ap-
            plication for an amendment adding any new use to the
            registration  and  that pertains solely to such new use,
            shall not, without the written permission of the origi-
            nal  data submitter, be  considered by the Adminis-
            trator to support an application by  another  person
            during a period of ten years following  the date the Ad-
            ministrator  first registers the  pesticide,  except  that
            such permission  shall not be required in the case of
            defensive data.
               (ii) The period  of  exclusive data use  provided
            under clause (i) shall be extended 1 additional year for
            each 3 minor uses registered after the date of enact-
            ment of this clause  and within 7 years  of the  com-
            mencement of the exclusive use period, up  to  a  total
            of 3 additional years for all minor uses registered by
            the Administrator if the Administrator, in consultation
            with the Secretary of Agriculture, determines that,
            based on information provided by an applicant for reg-
            istration or a registrant, that—
                   (I)  there  are insufficient  efficacious alter-
               native registered pesticides available for the use;
                   (II) the alternatives to the minor use pesticide
               pose greater risks to the environment or human
               health;
                   (III) the  minor use pesticide plays or will play
               a significant part in managing pest resistance; or

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Sec. 3	FIFRA	18

                    (IV) the minor use pesticide plays or will play
                a significant part in an integrated pest manage-
                ment program.
            The registration of a pesticide for a  minor use on a
            crop grouping established by the Administrator shall
            be considered for purposes of this clause 1 minor use
            for each representative crop for which data are pro-
            vided in the  crop grouping. Any additional exclusive
            use period under this clause shall be modified as ap-
            propriate or terminated if the registrant voluntarily
            cancels  the product or deletes from  the  registration
            the minor uses which formed the basis for the exten-
            sion of the additional exclusive use period or if the Ad-
            ministrator determines that the registrant is not actu-
            ally marketing the product for such minor uses.
                (iii) Except as  otherwise  provided in clause (i),
            with respect  to data  submitted  after  December  31,
            1969, by an applicant or registrant to support an ap-
            plication for registration, experimental use permit,  or
            amendment adding a new use to  an existing registra-
            tion, to  support or maintain in effect  an existing reg-
            istration, or for reregistration,  the Administrator may,
            without the permission of the original data submitter,
            consider any such item of data in support of an appli-
            cation by  any other person (hereinafter in this sub-
            paragraph referred to  as the  "applicant") within the
            fifteen-year period  following the  date the data were
            originally submitted only if the applicant has made an
            offer to compensate the original data submitter and
            submitted  such offer  to the  Administrator  accom-
            panied by evidence of delivery to the original data sub-
            mitter of the offer. The terms  and  amount  of com-
            pensation  may be  fixed by agreement between the
            original data submitter and the applicant,  or, failing
            such agreement, binding arbitration  under this sub-
            paragraph. If, at the end of ninety days after the date
            of delivery to the original data submitter of the offer
            to compensate, the original data submitter and the ap-
            plicant have neither agreed on the amount and terms
            of compensation nor on a procedure  for reaching an
            agreement on the amount and terms  of compensation,
            either person may initiate binding arbitration proceed-
            ings by requesting  the Federal Mediation and Concil-
            iation Service to appoint an arbitrator from  the roster
            of arbitrators maintained by such Service. The proce-
            dure and rules of the Service shall be  applicable to the
            selection of such arbitrator and to  such arbitration
            proceedings, and the findings and determination of the
            arbitrator shall be final and conclusive, and  no official
            or court of the United States shall have power or juris-
            diction to review any such findings and determination,
            except for fraud,   misrepresentation, or other  mis-
            conduct by one of the parties to the arbitration or the
            arbitrator where  there is a  verified  complaint  with

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19	FIFRA	Sec. 3

            supporting affidavits attesting to specific instances of
            such fraud, misrepresentation,  or  other misconduct.
            The parties to the  arbitration  shall share equally in
            the payment of the  fee and expenses of the arbitrator.
            If the Administrator determines that an original data
            submitter has failed to  participate  in a  procedure for
            reaching an agreement or in an arbitration proceeding
            as  required by this  subparagraph, or failed to comply
            with the terms of an agreement or arbitration decision
            concerning compensation under this subparagraph, the
            original data submitter shall forfeit the  right to com-
            pensation for the use of the data in support of the ap-
            plication. Notwithstanding any other provision of this
            Act, if the Administrator determines that an applicant
            has failed to participate in a procedure for reaching an
            agreement or in  an  arbitration proceeding as required
            by  this subparagraph,  or failed to comply with the
            terms of an agreement or arbitration decision concern-
            ing compensation under  this subparagraph, the Ad-
            ministrator shall deny  the application or cancel the
            registration of the  pesticide  in  support  of which the
            data were  used  without  further hearing.  Before the
            Administrator takes action under either of the preced-
            ing two sentences, the Administrator shall furnish to
            the affected person, by certified mail, notice of intent
            to take action and allow fifteen  days from the date of
            delivery  of the notice  for the  affected person to re-
            spond.  If a registration  is denied  or canceled under
            this subparagraph, the Administrator may make such
            order  as the Administrator  deems appropriate con-
            cerning the continued sale and use of existing stocks
            of such pesticide. Registration action by  the Adminis-
            trator shall not be delayed pending the fixing of com-
            pensation.
               (iv) After expiration of any  period of exclusive use
            and any period for which compensation is required for
            the use of an item  of data under clauses (i), (ii), and
            (iii), the Administrator may consider such item of data
            in  support of an application by any other applicant
            without the permission of the original data submitter
            and without an offer having been received to com-
            pensate the original data submitter  for the use of such
            item of data.
               (v) The period  of exclusive use provided under
            clause (ii) shall not take effect until  1 year after enact-
            ment of this clause, except where an applicant or reg-
            istrant is applying  for the registration of a  pesticide
            containing  an active ingredient not previously reg-
            istered.
               (vi) With respect to data  submitted after the date
            of enactment of this clause  by an applicant or reg-
            istrant to support an amendment adding a new use to
            an  existing registration that  does not retain any pe-
            riod of exclusive use, if such data  relates solely to  a

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Sec. 3	FIFRA	20

            minor use of a pesticide, such data shall not, without
            the written permission of the original data submitter,
            be considered by the Administrator to support an ap-
            plication for a minor use by another person during the
            period of 10 years following the date of submission of
            such data. The applicant or registrant at the time the
            new minor use is requested shall notify the Adminis-
            trator that to the best of their knowledge the exclusive
            use period for the pesticide has expired and that the
            data pertaining solely to the minor use of a pesticide
            is eligible for the provisions  of this paragraph. If the
            minor use registration which  is supported by data sub-
            mitted pursuant to this subsection is voluntarily can-
            celed or if such data are subsequently used to support
            a nonminor use, the data shall no longer be subject to
            the exclusive use provisions of this clause but shall in-
            stead be considered by the Administrator in  accord-
            ance with the provisions of clause (i), as appropriate.
            (G) If the applicant is requesting that the  registration
        or amendment to the registration of a pesticide be expe-
        dited, an explanation of the basis for the request must be
        submitted,  in accordance with paragraph (10)  of this sub-
        section.
        (2) DATA IN SUPPORT OF REGISTRATION.—
            (A) IN  GENERAL.—The  Administrator  shall  publish
        guidelines specifying the kinds of information which  will
        be required to support  the registration of a pesticide  and
        shall revise such guidelines from time to time. If thereafter
        the Administrator requires any additional kind of informa-
        tion under subparagraph (B) of this paragraph,  the Admin-
        istrator shall permit sufficient time  for applicants to ob-
        tain such additional information.  The Administrator, in es-
        tablishing standards for data requirements for the  reg-
        istration of pesticides with  respect to minor  uses, shall
        make such standards commensurate with the  anticipated
        extent of use, pattern of use, the public health and agricul-
        tural need for such minor use, and the level and degree of
        potential beneficial or adverse effects on man and the envi-
        ronment. The Administrator shall not require  a person to
        submit, in relation to a registration or reregistration  of a
        pesticide for minor agricultural  use under this Act,  any
        field residue data from a geographic area where the  pes-
        ticide will not be  registered for such use. In the develop-
        ment of these standards, the Administrator shall consider
        the economic factors of potential national  volume of  use,
        extent of distribution, and the impact of the cost of meet-
        ing the requirements on the incentives for any potential
        registrant to undertake the development of the required
        data.  Except as  provided by section 10, within 30 days
        after the Administrator registers  a pesticide under this Act
        the Administrator shall make available to  the public the
        data called for in the registration statement together with
        such  other scientific  information  as the  Administrator
        deems relevant to the Administrator's decision.

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21	FIFRA	Sec. 3

            (B) ADDITIONAL DATA.—(i) If the Administrator deter-
        mines that additional data are required to maintain in ef-
        fect an existing registration of a pesticide, the Adminis-
        trator shall notify all existing registrants of the pesticide
        to which the determination relates and provide a list of
        such registrants to any interested person.
            (ii)  Each registrant of such pesticide shall provide evi-
        dence within ninety days after receipt of notification that
        it is taking appropriate steps to secure the additional data
        that are required. Two or more registrants may agree to
        develop jointly, or to share in the cost of developing, such
        data if they agree and advise the Administrator of their in-
        tent within ninety days after  notification. Any registrant
        who agrees to share in the cost of producing the data shall
        be entitled to examine and rely upon such data in  support
        of maintenance of such  registration.  The  Administrator
        shall issue a notice of intent to suspend the  registration of
        a pesticide in accordance with the procedures prescribed
        by  clause  (iv)  if a registrant fails  to comply with this
        clause.
            (iii) If, at the end  of  sixty days after advising  the Ad-
        ministrator of their agreement to develop jointly, or share
        in the cost of developing data, the registrants have  not fur-
        ther agreed on the terms  of the data development arrange-
        ment or on a procedure for reaching such agreement, any
        of such registrants  may  initiate binding arbitration pro-
        ceedings by requesting the Federal Mediation and Concil-
        iation Service to appoint an arbitrator from the roster of
        arbitrators maintained by such Service. The  procedure and
        rules of the Service shall be applicable to the selection of
        such arbitrator  and to such arbitration proceedings, and
        the findings and determination of the arbitrator shall be
        final and conclusive, and  no official or court of the United
        States  shall have power or jurisdiction to review any such
        findings and determination, except for fraud, misrepresen-
        tation, or other misconduct by one  of the parties to the ar-
        bitration or the arbitrator where  there is a verified com-
        plaint  with supporting affidavits  attesting  to specific in-
        stances of such fraud, misrepresentation,  or  other mis-
        conduct. All parties to  the  arbitration shall share equally
        in the  payment of the fee and expenses of  the arbitrator.
        The Administrator shall issue a notice of intent to suspend
        the registration of a pesticide in accordance with the  proce-
        dures prescribed by clause (iv) if a registrant fails to com-
        ply with this clause.
            (iv) Notwithstanding  any other provision of this Act, if
        the Administrator determines that a registrant, within the
        time required by the Administrator, has failed to take ap-
        propriate steps to secure  the data required under this sub-
        paragraph,  to  participate  in a  procedure for reaching
        agreement concerning a  joint data development arrange-
        ment under this subparagraph or in  an arbitration pro-
        ceeding as  required by this  subparagraph, or to comply
        with the terms of an agreement or arbitration decision con-

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Sec. 3	FIFRA	22

        cerning a joint data development arrangement under this
        subparagraph, the Administrator may issue a notice of in-
        tent to  suspend such registrant's  registration of the pes-
        ticide for which additional data is required. The Adminis-
        trator may include in the notice of intent to suspend such
        provisions  as  the Administrator deems appropriate con-
        cerning the continued sale  and use of existing stocks of
        such pesticide. Any  suspension proposed under this sub-
        paragraph  shall become final and effective at the end of
        thirty days from receipt by  the registrant of the notice of
        intent to suspend, unless during that time a request for
        hearing is made by a person adversely affected  by the no-
        tice or the  registrant has satisfied the Administrator that
        the registrant has complied fully with the requirements
        that served as a basis for the notice of intent to suspend.
        If  a hearing is requested,  a  hearing  shall be  conducted
        under section 6(d) of this Act.  The only matters  for resolu-
        tion at  that hearing shall be whether the registrant  has
        failed to take  the action that served as the basis for the
        notice of intent to suspend the registration of the pesticide
        for which additional data is  required, and whether the Ad-
        ministrator's determination  with respect to the disposition
        of  existing  stocks is consistent with  this Act.  If a hearing
        is  held, a decision after completion  of such hearing shall
        be  final. Notwithstanding any other provision of this Act,
        a hearing shall be held and a determination made within
        seventy-five days after receipt of a request for such hear-
        ing. Any registration suspended under this subparagraph
        shall be reinstated by the Administrator if the Adminis-
        trator determines that  the  registrant has complied fully
        with the requirements that  served as a basis for the sus-
        pension of the  registration.
            (v) Any data submitted  under  this subparagraph shall
        be  subject to the provisions  of paragraph (1)(D).  Whenever
        such data are submitted jointly by  two or more registrants,
        an agent shall be agreed on at the time  of the joint sub-
        mission to handle any subsequent  data compensation mat-
        ters for  the joint submitters  of such data.
            (vi) Upon the request of a  registrant the Administrator
        shall, in the case of a minor use,  extend the deadline for
        the production of residue chemistry data under this sub-
        paragraph  for data required solely to support that minor
        use until the final deadline for submission of data under
        section 4 for the other uses  of the pesticide established as
        of the date of enactment of the Food Quality Protection Act
        of  1996, if—
                (I) the data to support other uses of the pesticide
            on a food are being provided;
                (II) the registrant, in  submitting  a request for
            such an extension,  provides a schedule, including in-
            terim dates to  measure progress, to assure that the
            data production will be completed  before the expira-
            tion of the extension period;

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23	FIFRA	Sec. 3

                (III) the Administrator has determined that such
            extension will not significantly delay the Administra-
            tor's schedule for issuing a reregistration eligibility de-
            termination required under section 4; and
                (IV) the Administrator has determined that based
            on  existing data, such  extension would  not signifi-
            cantly increase the  risk of any unreasonable  adverse
            effect  on  the  environment.1  If the   Administrator
            grants an  extension under this clause, the Adminis-
            trator shall monitor the development of the data and
            shall ensure that the registrant is meeting the sched-
            ule for the production of the data. If the Administrator
            determines that the registrant is not meeting or has
            not met the schedule for  the production of such data,
            the  Administrator may  proceed  in accordance with
            clause (iv) regarding the  continued registration of the
            affected products with the minor use and shall inform
            the public of such action. Notwithstanding the provi-
            sions of this clause, the Administrator may take action
            to modify or revoke  the extension under this clause  if
            the Administrator determines that the extension for
            the minor  use may cause an unreasonable adverse ef-
            fect on the environment. In such circumstance, the Ad-
            ministrator shall provide, in writing to the registrant,
            a notice revoking the extension of time for submission
            of data. Such data shall instead be  due in  accordance
            with the date established by the Administrator for the
            submission of the data.
            (vii) If the registrant does not commit to support  a
        specific minor  use of the pesticide, but  is supporting and
        providing data in a timely and adequate fashion to support
        uses of the pesticide on a food, or if all uses of the pes-
        ticide are nonfood uses and the registrant does not commit
        to support a specific minor use of the pesticide but is sup-
        porting and providing data in a timely and adequate fash-
        ion to support  other nonfood uses of the pesticide, the Ad-
        ministrator, at the written request of the registrant, shall
        not take any action pursuant to this clause in regard to
        such unsupported minor use until the final  deadline estab-
        lished as of the date of enactment of the Food Quality Pro-
        tection Act of 1996,  for the submission of data under sec-
        tion 4 for the  supported uses identified pursuant  to this
        clause unless the Administrator determines that the  ab-
        sence of the data is significant enough to cause human
        health or environmental concerns. On the basis of such de-
        termination, the Administrator may refuse  the request for
        extension by the registrant.  Upon receipt  of the request
        from the registrant, the Administrator shall publish in the
        Federal Register a notice of the receipt of the request and
        the effective date upon which  the uses not being supported
        will be  voluntarily deleted from the registration pursuant
 'Indentation of the following sentences of this clause is so in original (as added by sec.
201(cXD of P.L. 104-170). Probably should be indented the same as flush matter of this clause.

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Sec. 3	FIFRA	24

        to section 6(f)(l). If the Administrator grants an extension
        under this clause, the Administrator shall monitor the de-
        velopment of the data for the uses being supported and
        shall ensure that the registrant is meeting the schedule for
        the  production of such  data.  If the Administrator deter-
        mines that the registrant is not meeting or has not met
        the  schedule for the production of such data, the Adminis-
        trator may proceed in accordance with clause (iv)  of this
        subparagraph  regarding  the continued registration of the
        affected products with the minor and other uses and shall
        inform the public of such action in accordance with section
        6(f)(2). Notwithstanding the provisions of this clause,  the
        Administrator may  deny, modify, or revoke the temporary
        extension under this subparagraph if the  Administrator
        determines that the continuation of the minor use may
        cause an unreasonable adverse effect on the environment.
        In the event of modification or revocation,  the Adminis-
        trator shall provide, in writing, to the registrant a notice
        revoking the temporary extension and establish a new ef-
        fective date by which the minor use shall be deleted from
        the  registration.
            (viii)(I) If data required to support registration  of a
        pesticide under subparagraph (A) is requested by  a Fed-
        eral or State regulatory authority, the Administrator shall,
        to the extent  practicable,  coordinate data  requirements,
        test protocols,  timetables, and standards of review and re-
        duce burdens and redundancy caused to the registrant by
        multiple requirements on the registrant.
            (II) The Administrator  may enter into a  cooperative
        agreement with a State to carry out subclause (I).
            (Ill) Not later than 1 year after the date of enactment
        of this clause,  the Administrator shall develop a process to
        identify and assist in alleviating future disparities between
        Federal and State data requirements.
            (C)  SIMPLIFIED PROCEDURES.—Within  nine  months
        after the date  of enactment of this subparagraph, the Ad-
        ministrator shall, by regulation, prescribe simplified proce-
        dures for the registration of pesticides, which shall include
        the  provisions  of subparagraph (D) of this paragraph.
            (D) EXEMPTION.—No applicant  for  registration of  a
        pesticide who  proposes to purchase a registered pesticide
        from another  producer  in order to formulate such  pur-
        chased pesticide into the pesticide that is the subject of the
        application shall be  required to—
                (i) submit  or cite data  pertaining  to such  pur-
            chased product; or
                (ii) offer to pay reasonable compensation otherwise
            required by paragraph (1)(D) of this  subsection for the
            use of any such data.
            (E)  MINOR USE WAIVER.—In handling the registration
        of a pesticide  for  a minor use, the Administrator  may
        waive otherwise applicable  data requirements if the Ad-
        ministrator determines that the absence of such data will
        not  prevent the Administrator from determining—

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25 _ FIFRA _ Sec. 3

                (i) the incremental  risk presented by the minor
            use of the pesticide; and
                (ii) that such risk, if any, would not be an unrea-
            sonable adverse effect on the environment.
        (3) TIME FOR ACTING WITH RESPECT TO APPLICATION. —
            (A) IN GENERAL. — The Administrator shall review the
        data after receipt of the  application and shall, as expedi-
        tiously as possible, either register the pesticide in accord-
        ance with paragraph (5),  or notify the applicant of the Ad-
        ministrator's determination  that it  does not comply  with
        the provisions of the Act in accordance with paragraph (6).
            (B) IDENTICAL OR SUBSTANTIALLY SIMILAR. — (i) The Ad-
        ministrator shall,  as expeditiously as possible, review and
        act on any  application  received  by the  Administrator
                (I) proposes the initial or amended registration of
            an  end-use pesticide that,  if registered  as proposed,
            would be identical or substantially similar in composi-
            tion and  labeling to a currently-registered  pesticide
            identified in the application, or that would differ in
            composition  and  labeling  from  such  currently-reg-
            istered pesticide only in ways that would not  signifi-
            cantly increase the risk  of unreasonable adverse ef-
            fects on the environment; or
                (II) proposes an amendment to the registration of
            a registered pesticide that  does not require  scientific
            review of data.
            (ii)  In expediting the review of an application for an
        action described in clause (i), the Administrator shall —
                (I) within 45 days  after receiving the application,
            notify the registrant whether or not the application is
            complete and, if the application is found to be incom-
            plete, reject the application;
                (II) within 90 days after receiving a complete ap-
            plication,  notify the registrant  if the application has
            been granted or denied; and
                (III) if the application  is denied,  notify the reg-
            istrant in writing of the specific reasons for the denial
            of the application.
            (C)  MINOR USE REGISTRATION. —
                (i) The Administrator  shall,  as expeditiously  as
            possible, review and act on any  complete  application —
                    (I) that proposes the initial registration of a
                new pesticide active ingredient if the active ingre-
                dient is proposed to be  registered solely for minor
                uses, or proposes a registration amendment solely
                for minor uses to an existing registration; or
                    (II) for a registration or a registration amend-
                ment that proposes significant minor  uses.
                (ii) For the purposes of clause (i) —
                    (I)  the term  "as expeditiously  as  possible"
                means that the Administrator shall,  to the great-
                est extent practicable, complete a review and  eval-
                uation of all data,  submitted with a  complete ap-

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Sec. 3 _ FIFRA _ 26

                plication, within 12 months after the submission
                of the complete application, and the failure of the
                Administrator to complete such a review and eval-
                uation under clause (i) shall not be subject to judi-
                cial review; and
                   (II) the term "significant minor uses" means 3
                or more minor uses proposed for every  nonminor
                use, a minor  use that would, in the judgment of
                the Administrator, serve as a replacement for any
                use which has been canceled in the 5 years  pre-
                ceding the  receipt of the  application, or a minor
                use that in  the opinion of the Administrator would
                avoid the reissuance of an emergency exemption
                under section 18 for that minor use.
            (D)  ADEQUATE  TIME FOR SUBMISSION  OF MINOR  USE
        DATA. — If a registrant makes  a request for  a minor use
        waiver, regarding data required by the Administrator, pur-
        suant to paragraph  (2)(E), and if the Administrator denies
        in whole or in part such data  waiver request, the  reg-
        istrant shall  have  a  full-time  period  for providing such
        data.  For purposes  of this subparagraph, the term "full-
        time period" means the time period originally established
        by the Administrator  for  submission of such data, begin-
        ning with the date  of receipt by the registrant of the Ad-
        ministrator's notice  of denial.
        (4) NOTICE OF APPLICATION. — The Administrator shall pub-
    lish in the Federal Register, promptly after receipt of the state-
    ment and other data required pursuant to paragraphs (1) and
    (2), a notice  of each application for registration of any pesticide
    if it contains any new active ingredient or if it would entail a
    changed use pattern. The notice shall provide for a period of
    30 days in which any Federal agency  or any  other interested
    person may comment.
        (5) APPROVAL OF REGISTRATION. — The Administrator shall
    register a pesticide if the Administrator determines that, when
    considered with any restrictions  imposed under subsection
            (A) its composition is such as to warrant the proposed
        claims for it;
            (B) its labeling and other material required to be sub-
        mitted comply with the requirements of this Act;
            (C) it will perform  its intended function without un-
        reasonable adverse effects on the environment; and
            (D)  when used  in  accordance with widespread and
        commonly recognized practice it will not generally  cause
        unreasonable adverse effects on the environment.
    The Administrator shall not make any lack of essentiality a
    criterion for denying registration of any pesticide. Where two
    pesticides meet the requirements of this paragraph, one should
    not be registered in preference to the other. In considering an
    application for the registration of a pesticide,  the Adminis-
    trator may waive data requirements pertaining to efficacy,  in
    which event the Administrator may register the pesticide with-
    out determining that the pesticide's composition is such as  to

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27	FIFRA	Sec. 3

    warrant proposed claims of efficacy. If a pesticide is found to
    be efficacious by any State under section 24(c) of this Act,  a
    presumption is established that the Administrator shall waive
    data requirements pertaining to efficacy for use of the pesticide
    in such State.
        (6) DENIAL OF REGISTRATION.—If the Administrator deter-
    mines that the requirements of paragraph (5)  for registration
    are not satisfied, the Administrator shall notify the applicant
    for registration of the Administrator's determination and of the
    Administrator's reasons (including the factual  basis) therefor,
    and that, unless the  applicant corrects  the conditions and noti-
    fies the Administrator thereof during the 30-day  period begin-
    ning with the day after the date on which the  applicant re-
    ceives the notice, the Administrator may refuse to register the
    pesticide.  Whenever the Administrator refuses to register  a
    pesticide,  the Administrator shall notify the applicant of the
    Administrator's decision and of the Administrator's reasons (in-
    cluding the factual  basis) therefor. The  Administrator shall
    promptly publish in the Federal Register notice of such denial
    of registration  and  the  reasons therefor.  Upon such notifica-
    tion, the  applicant for registration or  other interested person
    with the concurrence of the applicant shall have the same rem-
    edies as provided for in section 6.
        (7) REGISTRATION UNDER SPECIAL CIRCUMSTANCES.—Not-
    withstanding the provisions of paragraph (5)—-
           (A) The Administrator may conditionally register or
        amend the  registration of a pesticide if the Administrator
        determines that (i) the pesticide  and proposed use  are
        identical  or substantially similar to any  currently  reg-
        istered pesticide and  use thereof,  or  differ only in  ways
        that would  not significantly increase the risk of unreason-
        able adverse effects on the environment, and (ii) approving
        the registration or amendment in the manner proposed by
        the applicant would not significantly  increase the risk of
        any unreasonable adverse effect on the environment.  An
        applicant seeking conditional  registration or amended reg-
        istration under this subparagraph  shall submit such data
        as would be required to obtain registration of a similar
        pesticide under paragraph (5). If the applicant is unable to
        submit an item of data because it has not yet been gen-
        erated, the  Administrator may register or amend the reg-
        istration of the pesticide under such conditions as will re-
        quire the submission of such  data not later than the time
        such  data are  required to be submitted with respect to
        similar pesticides already registered under this Act.
           (B) The Administrator may conditionally amend  the
        registration of a pesticide to permit additional uses of such
        pesticide notwithstanding that data concerning the pes-
        ticide  may  be insufficient to  support  an unconditional
        amendment, if the Administrator determines that (i) the
        applicant has submitted satisfactory data pertaining to the
       proposed additional use, and (ii) amending the registration
       in the manner proposed by the applicant would not signifi-
       cantly increase the risk of any unreasonable adverse effect

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Sec. 3	FIFRA	28

        on the environment. Notwithstanding the foregoing provi-
        sions of this subparagraph, no registration of a pesticide
        may be amended to permit an additional use of such pes-
        ticide if the Administrator has issued a notice stating that
        such pesticide, or any ingredient thereof, meets or exceeds
        risk criteria associated in whole or in part with human di-
        etary exposure  enumerated in regulations  issued  under
        this Act,  and during the pendency of any risk-benefit eval-
        uation initiated  by such notice, if (I) the additional  use of
        such pesticide involves a major food or feed crop, or (II) the
        additional use of such  pesticide involves a minor food or
        feed crop and the Administrator determines, with the con-
        currence  of the Secretary of Agriculture, there is available
        an effective alternative  pesticide that does not meet or ex-
        ceed such risk criteria. An applicant seeking amended reg-
        istration  under this subparagraph shall submit such data
        as would be required to obtain  registration of a  similar
        pesticide under paragraph (5). If the applicant is unable to
        submit an item  of data (other than data pertaining to the
        proposed additional use) because it has not yet been gen-
        erated, the  Administrator may  amend  the  registration
        under such conditions  as will require the submission of
        such data not later than the  time such data are required
        to be submitted with respect  to similar pesticides already
        registered under this Act.
            (C) The Administrator may  conditionally register a
        pesticide containing an active ingredient not contained in
        any currently registered pesticide for a period reasonably
        sufficient for the  generation  and submission of required
        data (which are lacking because a period reasonably suffi-
        cient for generation of  the data has not elapsed since  the
        Administrator first imposed the data requirement)  on  the
        condition that by the  end of such period the Administrator
        receives such data and  the data do not  meet or exceed risk
        criteria enumerated in regulations issued under this Act,
        and on such other conditions as the  Administrator may
        prescribe. A conditional registration under  this subpara-
        graph shall  be  granted only if  the Administrator deter-
        mines that use of the pesticide during such period will not
        cause any unreasonable adverse effect on the environment,
        and that use of the pesticide is in the public interest.
        (8)  INTERIM  ADMINISTRATIVE REVIEW.—Notwithstanding
    any other provision  of this Act, the Administrator may not ini-
    tiate  a  public interim administrative review process to develop
    a risk-benefit evaluation of the ingredients of a pesticide or any
    of its uses prior to initiating a formal action to cancel, suspend,
    or deny registration of such pesticide, required under this Act,
    unless such interim administrative process is based on a vali-
    dated test or other significant evidence raising  prudent con-
    cerns of unreasonable  adverse risk to man or to the environ-
    ment. Notice of the  definition of the terms "validated test" and
    "other significant evidence" as used herein shall be published
    by the Administrator in the Federal Register.
        (9) LABELING.—

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29	FIFRA	Sec. 3

            (A) ADDITIONAL  STATEMENTS.—Subject to  subpara-
        graphs (B) and (C), it shall not be a violation of this Act
        for a registrant to modify the labeling of an antimicrobial
        pesticide product to include relevant information on prod-
        uct efficacy, product composition, container composition or
        design, or other characteristics that do not  relate  to  any
        pesticidal claim or pesticidal activity.
            (B) REQUIREMENTS.—Proposed  labeling information
        under subparagraph (A) shall not be false or misleading,
        shall not conflict with or detract from any statement re-
        quired by law or the  Administrator as a condition  of  reg-
        istration, and shall be substantiated on the request of the
        Administrator.
            (C) NOTIFICATION AND DISAPPROVAL.—
                (i) NOTIFICATION.—A registration may be modified
            under subparagraph (A) if —
                    (I) the registrant notifies the Administrator in
                writing not later than 60 days  prior to distribution
                or sale of a product bearing the modified labeling;
                and
                    (II)  the Administrator  does not  disapprove of
                the modification under clause (ii).
                (ii) DISAPPROVAL.—Not  later than  30 days after
            receipt of a notification  under clause (i), the Adminis-
            trator may disapprove the modification by sending the
            registrant notification in writing stating that the pro-
            posed language is not acceptable and stating the rea-
            sons why the Administrator finds  the proposed modi-
            fication unacceptable.
                (iii) RESTRICTION ON SALE.—A registrant may not
            sell or distribute a product  bearing a disapproved
            modification.
                (iv)  OBJECTION.—A  registrant may file an objec-
            tion in writing to a disapproval under  clause  (ii) not
            later than 30  days  after receipt of notification of the
            disapproval.
                (v) FINAL ACTION.—A decision by  the Adminis-
           trator following receipt and  consideration of an objec-
           tion filed under clause (iv) shall be considered  a final
            agency action.
           (D)  USE  DILUTION.—The  label or labeling required
        under this Act for an antimicrobial pesticide  that is  or may
        be diluted for use  may have a different statement  of cau-
        tion or protective measures for use of the recommended di-
        luted solution of the pesticide than for use of a concentrate
        of the pesticide if the Administrator determines that —
                (i) adequate data have been submitted to support
           the  statement proposed  for the diluted  solution uses;
           and
                (ii) the label or  labeling  provides adequate  protec-
           tion for exposure to the diluted solution of the  pes-
           ticide.
        (10) EXPEDITED REGISTRATION OF PESTICIDES.—

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Sec. 3	FIFRA	30

            (A) Not later than 1 year after the date of enactment
        of this paragraph, the Administrator shall, utilizing public
        comment, develop procedures and guidelines, and expedite
        the review of an application for registration of a pesticide
        or an amendment to a  registration  that satisfies such
        guidelines.
            (B) Any application for registration or an amendment,
        including biological and  conventional  pesticides,  will  be
        considered for expedited review under this paragraph. An
        application for registration or an amendment shall qualify
        for expedited review if use of the pesticide proposed by the
        application may reasonably be expected to accomplish 1 or
        more of the following:
                (i) Reduce the risks of pesticides to human health.
                (ii) Reduce the risks of pesticides to nontarget or-
            ganisms.
                (iii)  Reduce  the potential for  contamination of
            groundwater, surface water, or other valued environ-
            mental resources.
                (iv) Broaden the  adoption of integrated pest man-
            agement strategies,  or make such strategies more
            available or more effective.
            (C) The Administrator,  not later than 30 days after re-
        ceipt of an application for expedited  review,  shall notify
        the applicant whether the application is complete.  If it is
        found to be incomplete, the Administrator may either re-
        ject the request for expedited review or ask the applicant
        for  additional information to satisfy the guidelines devel-
        oped under subparagraph (A).
     (d) CLASSIFICATION OF PESTICIDES.—
        (1) CLASSIFICATION FOR GENERAL USE, RESTRICTED USE, OR
     BOTH.—
            (A) As a part of the registration of a pesticide the Ad-
        ministrator shall classify it as being for general use or for
        restricted use. If the Administrator determines that some
        of the uses for which  the pesticide is registered should be
        for  general use and  that other uses  for which it  is reg-
        istered should  be for restricted use, the Administrator
        shall classify it  for both general use and restricted use.
        Pesticide uses may be classified by regulation on the initial
        classification and registered pesticides may be classified
        prior to reregistration. If some of the uses of the pesticide
        are classified for general use and other uses are classified
        for restricted use, the directions relating to  its general
        uses  shall be  clearly separated and  distinguished  from
        those directions relating to its restricted uses. The Admin-
        istrator may require that its packaging and labeling for re-
        stricted uses shall be clearly distinguishable from its pack-
        aging and labeling for general uses.
            (B) If the Administrator determines that the pesticide,
        when applied in accordance with its directions  for  use,
        warnings and cautions and for the uses for which it is reg-
        istered, or for one or more of such uses, or in accordance
        with a widespread and commonly recognized practice, will

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31	FIFRA	Sec. 3

        not generally cause unreasonable adverse effects on  the
        environment, the Administrator will classify the pesticide,
        or the particular use or uses of the pesticide to which the
        determination applies, for general use.
            (C) If the Administrator determines that the pesticide,
        when applied in accordance  with its  directions for use,
        warnings and cautions and for the uses for which it is reg-
        istered, or for one or more of such uses, or in accordance
        with a widespread and commonly recognized practice, may
        generally cause, without additional regulatory restrictions,
        unreasonable adverse  effects on the  environment, includ-
        ing injury  to the applicator, the Administrator shall clas-
        sify the pesticide, or the particular use or uses to which
        the determination applies, for restricted use:
                (i) If the Administrator classifies a pesticide, or
            one or more uses  of such pesticide, for restricted  use
            because of a determination that the acute dermal or
            inhalation toxicity of the pesticide presents a hazard
            to the  applicator or other persons, the pesticide shall
            be applied  for any use to which the restricted classi-
            fication applies only by or under the direct supervision
            of a certified applicator.
                (ii) If the Administrator  classifies a pesticide, or
            one or more uses  of such pesticide, for restricted  use
            because of a determination  that its use without addi-
            tional  regulatory restriction may cause unreasonable
            adverse effects on the environment, the pesticide shall
            be applied for any use to which the determination ap-
            plies only by or under the direct supervision of a cer-
            tified applicator, or subject  to such other restrictions
            as the Administrator may provide by regulation. Any
            such regulation shall be reviewable in the appropriate
            court of appeals  upon petition of a person adversely af-
            fected  filed  within 60 days of the publication of the
            regulation in final form.
        (2) CHANGE IN  CLASSIFICATION.—If the Administrator de-
    termines that a change in the classification of any use of a pes-
    ticide from general use to restricted use is necessary to prevent
    unreasonable adverse effects on the environment, the Adminis-
    trator shall notify the registrant of  such  pesticide of such de-
    termination at  least forty-five days before making the change
    and shall publish the proposed change in the Federal Register.
    The registrant, or other interested person with the concurrence
    of the  registrant, may  seek  relief  from such determination
    under section 6(b).
        (3) CHANGE IN  CLASSIFICATION FROM RESTRICTED USE TO
    GENERAL USE.—The  registrant of any pesticide  with one  or
    more uses classified for restricted use may petition the Admin-
    istrator to change any  such classification  from  restricted to
    general use. Such petition shall set  out the basis for the reg-
    istrant's position  that restricted use classification is unneces-
    sary because classification of the pesticide  for  general use
    would not cause unreasonable  adverse effects  on the environ-
    ment. The Administrator, within sixty days after  receiving

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Sec. 3	FIFRA	32

    such petition, shall notify the registrant whether the petition
    has been granted or denied. Any denial shall contain an expla-
    nation therefor and any such denial shall be subject to judicial
    review under section 16 of this Act.
    (e) PRODUCTS WITH  SAME FORMULATION AND CLAIMS.—Prod-
ucts which have  the same  formulation,  are manufactured by the
same person, the labeling of which contains the same claims, and
the labels of which bear a  designation identifying the product as
the same pesticide may be registered as a single pesticide; and ad-
ditional names and labels shall be added to the registration by sup-
plemental statements.
    (f) MISCELLANEOUS.—
        (1) EFFECT OF CHANGE OF LABELING OR FORMULATION.—If
    the labeling or formulation for a pesticide is changed, the reg-
    istration shall be amended to reflect such change if the Admin-
    istrator determines that the change will not violate any  provi-
    sion of this Act.
        (2) REGISTRATION NOT A  DEFENSE.—In no event shall reg-
    istration of an article be construed as a defense for the com-
    mission of any offense under this Act. As long as no cancella-
    tion proceedings  are in effect registration of a  pesticide shall
    be prima facie  evidence  that the pesticide, its labeling and
    packaging comply with the registration provisions of the Act.
        (3) AUTHORITY TO CONSULT OTHER FEDERAL AGENCIES.—In
    connection with consideration of any registration or application
    for registration under this section, the Administrator may con-
    sult with any other Federal agency.
        (4)  MIXTURES OF  NITROGEN STABILIZERS AND FERTILIZER
    PRODUCTS.—Any mixture or other combination of—
            (A) 1 or more nitrogen stabilizers registered under this
        Act; and
            (B) 1 or more fertilizer products,
    shall not be subject to the provisions of this section or sections
    4, 5, 7,  15, and 17(a)(2) if the mixture or other combination is
    accompanied by the labeling required under this Act for the ni-
    trogen stabilizer contained in the mixture  or other combina-
    tion, the mixture or combination is mixed or combined  in  ac-
    cordance with  such  labeling, and the  mixture or combination
    does not contain any active ingredient other than the nitrogen
    stabilizer.
    (g) REGISTRATION REVIEW.—
        (1)(A) GENERAL  RULE.—The registrations of pesticides are
    to be periodically reviewed. The Administrator shall by regula-
    tion establish a  procedure for accomplishing the periodic  re-
    view of registrations. The goal of these regulations shall be a
    review of a pesticide's registration every 15 years. No registra-
    tion shall be canceled  as a result of the registration review
    process unless the Administrator follows the  procedures and
    substantive requirements of section 6.
        (B) LIMITATION.—Nothing in this subsection shall prohibit
    the Administrator from undertaking any other review of a pes-
    ticide pursuant to this Act.

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33	FIFRA	Sec. 3

        (2)(A) DATA.—The Administrator shall use the authority in
    subsection (c)(2)(B) to require the submission  of data  when
    such data are necessary for a registration review.
        (B) DATA  SUBMISSION, COMPENSATION, AND EXEMPTION.—
    For purposes of this subsection, the provisions  of subsections
    (c)(l), (c)(2)(B), and (c)(2)(D) shall be utilized for and be  appli-
    cable to any data required for registration review.
    (h)  REGISTRATION  REQUIREMENTS  FOR  ANTIMICROBIAL  PES-
TICIDES.—
        (1)  EVALUATION OF PROCESS.—To  the maximum  extent
    practicable consistent with the degrees of risk presented  by an
    antimicrobial pesticide and  the type of review  appropriate to
    evaluate the risks, the Administrator shall identify and evalu-
    ate  reforms to the antimicrobial registration  process  that
    would reduce review periods existing as of the  date of enact-
    ment of this subsection for antimicrobial pesticide product reg-
    istration applications and applications  for  amended registra-
    tion of antimicrobial pesticide products, including—
            (A) new antimicrobial active ingredients;
            (B) new antimicrobial end-use products;
            (C) substantially similar or identical antimicrobial pes-
        ticides; and
            (D) amendments to antimicrobial  pesticide registra-
        tions.
        (2) REVIEW TIME PERIOD  REDUCTION GOAL.—Each reform
    identified under paragraph (1) shall be designed to achieve the
    goal  of reducing the review  period following  submission of a
    complete application, consistent with the degree of risk, to a
    period of not more than—
            (A) 540 days for a new antimicrobial active ingredient
        pesticide registration;
            (B) 270 days  for a  new antimicrobial  use of a reg-
        istered active ingredient;
            (C) 120 days for any other new antimicrobial product;
            (D) 90  days for a  substantially similar  or identical
        antimicrobial product;
            (E) 90 days for an amendment to an antimicrobial reg-
        istration that does not require scientific review of data;
        and
            (F)  90 to  180  days  for an  amendment to  an
        antimicrobial registration that requires  scientific review of
        data and that is not otherwise described in this paragraph.
        (3) IMPLEMENTATION.—
            (A) PROPOSED RULEMAKING.—
                (i) ISSUANCE.—Not later than  270 days after the
            date of enactment  of this subsection,  the Adminis-
            trator shall publish in the Federal Register proposed
            regulations to accelerate and  improve  the  review of
            antimicrobial  pesticide  products designed  to  imple-
            ment, to the extent practicable, the goals set forth in
            paragraph (2).
                (ii)  REQUIREMENTS.—Proposed  regulations  issued
            under clause (i) shall—

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Sec. 3	FIFRA	34

                    (I) define  the  various classes of antimicrobial
                use patterns, including household, industrial, and
                institutional   disinfectants  and  sanitizing  pes-
                ticides, preservatives,  water treatment, and pulp
                and paper mill additives, and other such products
                intended to disinfect, sanitize, reduce, or mitigate
                growth  or  development of microbiological  orga-
                nisms, or  protect inanimate objects, industrial
                processes or systems,  surfaces, water,  or  other
                chemical substances from contamination, fouling,
                or deterioration caused by bacteria, viruses, fungi,
                protozoa, algae, or slime;
                    (II) differentiate the types of review under-
                taken for antimicrobial pesticides;
                    (III)  conform the degree and type  of review to
                the risks and  benefits presented by antimicrobial
                pesticides and the function of review under this
                Act, considering the use patterns of the product,
                toxicity, expected exposure, and product type;
                    (IV)  ensure that  the registration process is
                sufficient to maintain  antimicrobial pesticide effi-
                cacy and that antimicrobial pesticide  products
                continue to  meet  product performance standards
                and  effectiveness  levels  for  each type  of label
                claim made; and
                    (V) implement effective  and reliable deadlines
                for process management.
                (iii) COMMENTS.—In developing the proposed regu-
            lations, the Administrator shall solicit the views from
            registrants and other affected parties to maximize the
            effectiveness  of the rule development process.
            (B) FINAL REGULATIONS.—
                (i) ISSUANCE.—The Administrator shall issue final
            regulations not later than 240 days after  the close of
            the comment period for the proposed regulations.
                (ii) FAILURE TO MEET GOAL.—If a goal  described in
            paragraph  (2) is not met by the final regulations, the
            Administrator shall identify the goal, explain why the
            goal was not attained,  describe the element of the reg-
            ulations included instead,  and identify future steps to
            attain the goal.
                (iii) REQUIREMENTS.—In issuing final  regulations,
            the Administrator  shall—
                    (I) consider the establishment  of a certifi-
                cation  process  for  regulatory  actions involving
                risks that can be responsibly  managed, consistent
                with the degree of risk, in the  most cost-efficient
                manner;
                    (II) consider  the  establishment of a certifi-
                cation  process by  approved laboratories as an ad-
                junct to the review process;
                    (III)  use all appropriate and cost-effective re-
                view mechanisms,  including—

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35	FIFRA	Sec. 3

                        (aa) expanded use of notification and non-
                    notification procedures;
                        (bb) revised procedures for application re-
                    view; and
                        (cc) allocation of appropriate resources to
                    ensure    streamlined    management     of
                    antimicrobial pesticide registrations; and
                    (IV)  clarify  criteria for determination of  the
                completeness of an application.
            (C) EXPEDITED  REVIEW.—This subsection does not af-
        fect the requirements or extend the deadlines or review pe-
        riods contained in subsection (c)(3).
            (D) ALTERNATIVE REVIEW PERIODS.—If the final regula-
        tions to carry out this paragraph are not effective 630 days
        after the  date  of enactment of this  subsection, until  the
        final regulations become effective, the review period,  be-
        ginning on the  date of receipt by the Agency of a complete
        application, shall be—
                (i) 2 years for a new antimicrobial active ingredi-
            ent pesticide registration;
                (ii) 1 year  for a new  antimicrobial use of a reg-
            istered active ingredient;
                (iii) 180 days  for any other new antimicrobial
            product;
                (iv) 90  days for a substantially similar or identical
            antimicrobial product;
                (v) 90 days for an amendment to an antimicrobial
            registration that does not require scientific review of
            data;  and
                (vi)  240  days   for   an   amendment   to  an
            antimicrobial registration  that requires scientific re-
            view  of data and that is  not otherwise described in
            this subparagraph.
            (E) WOOD PRESERVATIVES.—An application for the reg-
        istration,  or for  an  amendment to the  registration, of a
        wood preservative product for which  a claim of pesticidal
        activity listed in  section  2(mm) is  made (regardless of any
        other  pesticidal claim that is made  with  respect to  the
        product) shall be reviewed by the Administrator within the
        same period as that established under this paragraph for
        an antimicrobial pesticide product application, consistent
        with the degree of risk posed by the  use of the wood pre-
        servative  product, if the  application requires the applicant
        to satisfy the same  data requirements as are required to
        support an application  for a  wood  preservative product
        that is an antimicrobial pesticide.
            (F) NOTIFICATION.—
                (i) IN GENERAL.—Subject to clause (iii), the Admin-
            istrator shall notify  an applicant  whether an applica-
            tion has been granted or denied not later than  the
            final  day of the appropriate review  period under this
            paragraph, unless the applicant and the Administrator
            agree to a later date.

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Sec. 4	FIFRA	36

                (ii) FINAL DECISION.—If the Administrator fails to
            notify an applicant  within the period of time required
            under clause  (i), the  failure  shall be considered an
            agency action unlawfully withheld or unreasonably de-
            layed for purposes  of judicial  review under chapter 7
            of title 5, United States Code.
                (iii)  EXEMPTION.—This subparagraph  does  not
            apply to  an application for  an antimicrobial pesticide
            that is filed under subsection (c)(3)(B) prior to 90 days
            after the date of enactment of this subsection.
        (4) ANNUAL REPORT.—
            (A)  SUBMISSION.—Beginning on the date  of enactment
        of this subsection and ending on  the date that the goals
        under paragraph (2) are achieved,  the Administrator shall,
        not later than March 1 of each year, prepare and submit
        an annual report to the Committee on Agriculture of the
        House of Representatives and  the  Committee  on Agri-
        culture, Nutrition, and Forestry of the Senate.
            (B)  REQUIREMENTS.—A report submitted under sub-
        paragraph (A) shall include a description of—
                (i) measures taken to reduce  the backlog of pend-
            ing registration applications;
                (ii) progress toward achieving reforms under this
            subsection; and
                (iii) recommendations to improve the activities of
            the Agency pertaining to antimicrobial registrations.
SEC. 4. [136a-l] REREGISTRATION OF REGISTERED PESTICIDES.
    (a) GENERAL RULE.—The Administrator shall reregister,  in ac-
cordance with this section, each  registered  pesticide containing any
active ingredient contained in any pesticide first registered before
November 1, 1984, except for any pesticide as  to which the Admin-
istrator has  determined,  after November 1, 1984, and  before the ef-
fective date of this section, that—
        (1) there are no outstanding data requirements; and
        (2) the requirements of section 3(c)(5) have been satisfied.
    (b)  REREGISTRATION PHASES.—Reregistrations   of  pesticides
under this section shall be carried out in the following phases:
        (1)  The  first phase  shall  include the listing under sub-
    section (c) of the active ingredients  of the pesticides that will
    be reregistered.
        (2) The second  phase shall include the submission to the
    Administrator under subsection (d) of notices by registrants re-
    specting their intention to seek reregistration, identification by
    registrants of missing and inadequate data for such pesticides,
    and commitments by registrants to replace such missing or in-
    adequate data within the applicable time period.
        (3) The third phase shall include submission to the Admin-
    istrator by registrants of the information required under sub-
    section (e).
        (4) The fourth phase shall include an independent, initial
    review by the Administrator under subsection  (f)  of submis-
    sions under phases two and  three, identification of outstanding

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37	FIFRA	Sec. 4

    data requirements, and the issuance, as necessary, of requests
    for additional data.
        (5) The fifth phase shall include the review by the Admin-
    istrator under subsection (g) of data submitted for reregistra-
    tion and appropriate regulatory action by the Administrator.
    (c) PHASE  ONE.—
        (1) PRIORITY FOR REREGISTRATION.—For purposes of the re-
    registration of the pesticides described in  subsection (a), the
    Administrator shall list the active ingredients of pesticides and
    shall give priority to, among others, active ingredients  (other
    than active ingredients for which registration standards have
    been issued before the effective date of this section) that—
            (A) are in use on or in food or feed and may result in
        postharvest residues;
            (B) may result  in residues  of potential toxicological
        concern in potable ground water, edible fish, or shellfish;
            (C) have been determined by the Administrator before
        the effective  date  of this  section to have significant out-
        standing data requirements; or
            (D) are used on crops, including in greenhouses and
        nurseries, where worker exposure  is most likely to occur.
        (2) REREGISTRATION LISTS.—For purposes of reregistration
    under this section, the Administrator shall by order—
            (A) not later than 70 days after the effective date of
        this section, list pesticide active ingredients for which reg-
        istration standards have been issued before such effective
        date;
            (B) not later than 4 months after such effective date,
        list the first  150 pesticide  active  ingredients,  as  deter-
        mined under paragraph (1);
            (C) not later than 7 months after such effective date,
        list the second 150  pesticide  active ingredients, as  deter-
        mined under paragraph (1); and
            (D) not later than 10 months after such effective date,
        list the remainder of the pesticide active ingredients,  as
        determined under paragraph (1).
    Each list shall be published in the Federal Register.
        (3) JUDICIAL  REVIEW.—The content of a list issued by the
    Administrator under paragraph  (2) shall  not be  subject  to
    judicial review.
        (4) NOTICE TO REGISTRANTS.—On the publication of a list
    of pesticide active ingredients under paragraph (2), the Admin-
    istrator shall send by certified mail to the  registrants  of the
    pesticides containing such active ingredients  a notice  of the
    time by which  the registrants are to notify the Administrator
    under subsection (d) whether the registrants intend to seek or
    not to seek reregistration of such pesticides.
    (d) PHASE Two-
        CD IN GENERAL.—The registrant of a pesticide that con-
    tains an active ingredient listed  under subparagraph (B), (C),
    or (D)  of  subsection (c)(2) shall submit to  the  Administrator,
    within the time period prescribed by paragraph (4), the notice
    described  in paragraph (2) and any information, commitment,
    or offer described in paragraph (3).

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Sec. 4	FIFRA	38

        (2) NOTICE OF INTENT TO SEEK OR NOT  TO SEEK  REREG-
    ISTRATION.—
            (A) The registrant of a pesticide containing an active
        ingredient listed under subparagraph (B), (C), or  (D) of
        subsection (c)(2) shall notify the Administrator by certified
        mail whether the registrant intends to seek or does not in-
        tend to seek reregistration of the pesticide.
            (B) If a registrant submits a notice  under  subpara-
        graph  (A) of an intention not to  seek reregistration of a
        pesticide, the  Administrator shall publish a notice  in the
        Federal Register stating that  such a notice has been sub-
        mitted.
        (3) MISSING OR INADEQUATE DATA.—Each registrant of a
    pesticide that contains an active ingredient listed under sub-
    paragraph (B), (C), or (D) of subsection (cK2) and for which the
    registrant submitted a notice under paragraph (2) of an inten-
    tion to seek reregistration of such  pesticide shall submit to the
    Administrator—
            (A) in accordance with regulations issued by the Ad-
        ministrator under section 3, an identification of—
                (i) all  data that are required by regulation to sup-
            port the registration  of the pesticide  with respect to
            such active ingredient;
                (ii) data that were submitted by the registrant
            previously in support of  the  registration  of the pes-
            ticide that are inadequate to meet such regulations;
            and
                (iii) data identified under clause (i) that have not
            been submitted to the Administrator; and
            (B) either—
                (i) a  commitment to  replace the data identified
            under subparagraph (A)(ii) and submit the data identi-
            fied under subparagraph (A)(iii) within the applicable
            time period prescribed by paragraph (4)(B); or
                (ii) an offer to share in the cost to be incurred by
            a person who has made a  commitment under clause (i)
            to replace or submit the data and an offer to submit
            to arbitration as described by section 3(c)(2)(B) with
            regard to such cost sharing.
    For purposes of a  submission by  a registrant under subpara-
    graph (A)(ii), data  are inadequate  if the data are derived from
    a study with respect to which  the  registrant is unable to make
    the certification prescribed by  subsection (e)(l)(G) that the reg-
    istrant possesses or has access to the raw data used in or gen-
    erated by such study. For purposes of a submission by a reg-
    istrant under such subparagraph, data shall  be considered to
    be inadequate if the data are derived from a study submitted
    before January 1,  1970, unless it is demonstrated to the satis-
    faction of the Administrator that  such data should be consid-
    ered to support the registration of the pesticide that  is to be
    reregistered.
        (4) TIME PERIODS.—
            (A) A submission under paragraph (2) or (3)  shall be
        made—

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39	FIFRA	Sec. 4

                (i) in the case of a  pesticide containing an active
            ingredient listed under  subsection (c)(2)(B), not later
            than  3 months after the date of publication of the list-
            ing of such active ingredient;
                (ii) in the case  of a  pesticide containing an active
            ingredient listed under  subsection (c)(2)(C), not later
            than  3 months after the date of publication of the list-
            ing of such active ingredient; and
                (iii) in the case of a pesticide containing an active
            ingredient listed under  subsection (c)(2)(D), not later
            than  3 months after the date of publication of the list-
            ing of such active ingredient.
        On application, the Administrator may extend  a time pe-
        riod prescribed by this subparagraph if the Administrator
        determines  that factors beyond the  control of the  reg-
        istrant prevent the registrant  from complying with such
        period.
            (B) A registrant shall submit data in accordance with
        a commitment entered into under paragraph (3)(B) within
        a reasonable period of time, as determined by the Adminis-
        trator, but not  more than 48 months after the date the
        registrant submitted the commitment. The Administrator,
        on application of a registrant, may extend the period pre-
        scribed by the preceding sentence by no more than 2 years
        if extraordinary circumstances beyond the control of the
        registrant prevent  the  registrant  from submitting  data
        within such prescribed period.  Upon application of a reg-
        istrant, the Administrator shall, in the case of a minor use,
        extend the deadline for the production of residue chemistry
        data under this subparagraph  for data required solely  to
        support that minor use until the final deadline for submis-
        sion of data under  this section for the other uses of the
        pesticide  established as of the  date  of enactment of the
        Food Quality Protection Act of 1996 if—
                (i) the data to support other uses of the pesticide
            on a food are being provided;
                (ii) the registrant, in submitting a request for such
            an extension  provides a schedule, including interim
            dates to measure progress, to assure that the data pro-
            duction will be completed before the expiration of the
            extension period;
                (iii) the Administrator has determined that such
            extension will not significantly delay the Administra-
            tor's schedule for issuing a reregistration eligibility de-
            termination required under this section; and
                (iv) the Administrator has  determined that based
            on  existing data, such  extension would not  signifi-
            cantly increase  the  risk of any unreasonable adverse
            effect on  the   environment.1  If the  Administrator
            grants an extension under this  subparagraph, the Ad-
            ministrator shall monitor the development of the data
  1 Indentation of the following sentences of this subparagraph is so in original (as added by
sec. 201(cX2) of P.L. 104-170). Probably should be indented the same as flush matter of this
subparagraph.

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Sec. 4	FIFRA	40

            and shall ensure that the registrant is meeting the
            schedule for the production of the data. If the Admin-
            istrator determines that the registrant is not meeting
            or has not met the schedule for the production of such
            data,  the Administrator may proceed in  accordance
            with clause (iv) of section 3(c)(2)(B) or other provisions
            of this section, as appropriate, regarding the continued
            registration  of the  affected products with the minor
            use and shall inform the public of such action.  Not-
            withstanding the provisions of this subparagraph, the
            Administrator may take action to modify or revoke the
            extension under  this subparagraph if the  Adminis-
            trator determines that the extension for the minor use
            may cause an unreasonable adverse effect on the envi-
            ronment.  In such  circumstance,  the  Administrator
            shall provide written notice to the registrant revoking
            the extension of time for submission of data. Such
            data shall instead be  due in accordance with the date
            then established by the Administrator for  submission
            of the data.
        (5) CANCELLATION AND REMOVAL.—
            (A)  If the registrant of a pesticide does not submit a
        notice under paragraph (2)  or  (3)  within the  time pre-
        scribed by paragraph (4)(A), the Administrator shall issue
        a notice of intent to cancel the registration of such reg-
        istrant for such pesticide and shall publish the notice in
        the Federal Register and allow 60 days for the  submission
        of comments on the notice. On expiration of such 60 days,
        the Administrator, by order  and without  a hearing, may
        cancel the registration or take such other action, including
        extension  of applicable time periods, as may be necessary
        to enable  reregistration of such pesticide by another per-
        son.
            (B)(i) If—
                (I) no registrant of a pesticide containing an active
            ingredient listed under subsection  (c)(2) notifies the
            Administrator under paragraph  (2) that the registrant
            intends to seek reregistration of any pesticide contain-
            ing that active ingredient;
                (II) no such registrant complies with paragraph
            (3)(A); or
                (III) no  such  registrant makes  a commitment
            under  paragraph (3)(B) to replace  or  submit all data
            described in  clauses (ii) and (iii) of paragraph (3)(A);
        the Administrator shall publish in the Federal Register a
        notice of intent  to remove the active ingredient from the
        list established under subsection (c)(2)  and a notice of in-
        tent to cancel the registrations of all pesticides containing
        such active ingredient and shall provide 60 days for com-
        ment on such notice.
            (ii) After the 60-day period has  expired, the Adminis-
        trator, by  order, may cancel any such registration without
        hearing, except that the Administrator shall not cancel a
        registration under this subparagraph if—

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41	FIFRA	Sec. 4

                (I) during the comment period  a person acquires
            the rights of the registrant in that registration;
                (II) during the comment period that person fur-
            nishes a notice of intent to reregister the pesticide in
            accordance with paragraph (2); and
                (III) not later than 120 days after the publication
            of the notice under this subparagraph, that person has
            complied with paragraph (3) and the fee prescribed by
            subsection (i)(l) has been paid.
        (6) SUSPENSIONS AND PENALTIES.—The Administrator shall
    issue a  notice of intent to suspend the registration of a pes-
    ticide in accordance with the procedures prescribed by section
    3(cX2)(B)(iv) if the Administrator determines that (A) progress
    is insufficient to ensure the submission of the data required for
    such pesticide  under a commitment made under paragraph
    (3)(B) within the time period prescribed by paragraph (4)(B) or
    (B) the registrant has not submitted such data to the Adminis-
    trator within such time period. If the registrant does not com-
    mit to support a specific minor use of the pesticide, but is sup-
    porting  and providing data  in a timely and  adequate fashion
    to support uses of the pesticide on a food, or if all uses of the
    pesticide are nonfood  uses and the registrant does not commit
    to support a specific minor use of the pesticide but is support-
    ing  and providing data in a timely and adequate fashion  to
    support  other nonfood uses of the pesticide, the Administrator,
    at the written request of the registrant, shall not take any  ac-
    tion pursuant to this paragraph in regard to such unsupported
    minor use until the final deadline established as of the date of
    enactment of the Food Quality Protection Act of 1996, for the
    submission of data under this section  for the supported uses
    identified pursuant to this paragraph unless the Administrator
    determines that the absence of the  data is significant enough
    to cause human health or environmental concerns. On such a
    determination the Administrator may refuse the request for  ex-
    tension by the registrant. Upon receipt of the request from the
    registrant, the Administrator shall publish in the Federal Reg-
    ister a notice of the receipt of the request and the effective date
    upon which the uses  not  being  supported will be voluntarily
    deleted from the registration pursuant  to section 6(f)(l). If the
    Administrator grants  an extension under this paragraph, the
    Administrator shall monitor the development of the  data  for
    the uses being supported and  shall ensure that the registrant
    is meeting the schedule for the production of such data. If the
    Administrator determines that the registrant is not meeting or
    has  not  met the schedule for the production of such data, the
    Administrator  may   proceed  in  accordance with  section
    3(c)(2)(B)(iv) regarding the  continued  registration of the  af-
    fected products with the minor and other uses and shall inform
    the public of such action in accordance with section 6(f)(2). Not-
    withstanding this subparagraph, the Administrator may deny,
    modify,  or revoke the temporary extension under this para-
    graph if the Administrator determines that the continuation of
    the minor use may cause an unreasonable adverse effect on the
    environment.  In the  event of  modification or revocation, the

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Sec. 4	FIFRA	42

    Administrator shall provide, in writing, to the registrant a no-
    tice revoking the temporary extension and establish a new ef-
    fective date by which the minor use shall be deleted from the
    registration.
    (e) PHASE THREE.—
        (1)  INFORMATION ABOUT STUDIES.—Each registrant  of  a
    pesticide that contains an active ingredient listed under sub-
    paragraph  (B), (C), or (D) of subsection (c)(2) who has submit-
    ted a notice under subsection (d)(2) of an intent to seek the re-
    registration of such pesticide shall  submit, in accordance with
    the  guidelines   issued  under   paragraph   (4),  to   the
    Administrator—
            (A) a summary of each study concerning the active in-
        gredient previously submitted by the registrant in support
        of the registration of a pesticide containing such active in-
        gredient and considered by the registrant to be  adequate
        to meet the requirements of section 3 and the regulations
        issued  under such section;
            (B) a summary of each study concerning the active in-
        gredient previously submitted by the registrant in support
        of the registration of a pesticide containing such active in-
        gredient that may not  comply with the  requirements of
        section 3 and the regulations issued under such section but
        which  the registrant  asserts should be deemed to comply
        with such requirements  and regulations;
            (C) a reformat of the  data from each study summa-
        rized under subparagraph (A) or (B) by the registrant con-
        cerning chronic  dosing,  oncogenicity,  reproductive effects,
        mutagenicity, neurotoxicity,  teratogenicity,  or  residue
        chemistry of the active  ingredient that were submitted to
        the Administrator before January 1, 1982;
            (D) where data described in subparagraph  (C) are not
        required for the active ingredient by regulations issued
        under  section 3, a reformat of acute and subchronic dosing
        data submitted by the registrant to the Administrator be-
        fore January  1, 1982, that  the registrant considers to be
        adequate to meet the requirements of section 3 and the
        regulations issued under such section;
            (E) an identification of data that are required to be
        submitted to the Administrator under section 6(a)(2) indi-
        cating  an adverse effect  of the pesticide;
            (F) an identification of any other information available
        that in the view of the registrant supports the registration;
            (G) a certification that the registrant or the Adminis-
        trator  possesses or has  access  to the raw data used in or
        generated by the studies that  the registrant summarized
        under  subparagraph  (A) or (B);
            (H) either—
                (i) a commitment to submit data to fill  each out-
            standing  data requirement  identified  by  the reg-
            istrant; or
                (ii) an offer to share in the cost of developing such
            data to be incurred by a person who has made a com-
            mitment under clause (i) to submit such data, and an

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43	FIFRA	Sec. 4

            offer to submit to arbitration as described by section
            3(c)(2)(B) with regard to such cost sharing; and
            (I) evidence of compliance with section 3(c)(l)(D)(ii)
        and  regulations issued  thereunder with regard  to  pre-
        viously submitted data as if the registrant were now seek-
        ing the original registration of the pesticide.
    A registrant  who submits a certification under  subparagraph
    (G) that  is false shall  be  considered to have  violated this Act
    and shall be  subject to the penalties prescribed by section 14.
        (2) TIME PERIODS.—
            (A) The information required by paragraph (1) shall be
        submitted to the Administrator—
                (i) in the case of a pesticide containing an active
            ingredient listed  under subsection (c)(2)(B), not later
            than 12 months  after the  date of publication of the
            listing of such active ingredient;
                (ii) in the case of a pesticide containing an active
            ingredient listed  under subsection (c)(2)(C), not later
            than 12 months  after the  date of publication of the
            listing of such active ingredient; and
                (iii) in the case of a pesticide containing an active
            ingredient listed  under subsection (c)(2)(D), not later
            than 12 months  after the  date of publication of the
            listing of such active ingredient.
            (B) A registrant shall submit data in accordance with
        a commitment entered into under paragraph (1)(H) within
        a reasonable period of time, as determined by the Adminis-
        trator, but not more  than 48  months  after the date  the
        registrant  submitted  the commitment under such  para-
        graph. The Administrator, on  application of a registrant,
        may extend the period prescribed by the preceding sen-
        tence by no more  than 2 years if extraordinary  cir-
        cumstances beyond the control of the registrant prevent
        the registrant from submitting data within such prescribed
        period. Upon application of a registrant, the Administrator
        shall, in  the case of a minor use, extend the deadline for
        the production  of residue chemistry data under this sub-
        paragraph  for data required solely to support that minor
        use until the final deadline for submission of data under
        this  section for the other uses  of the pesticide established
        as of the date of enactment of the Food Quality Protection
        Act of 1996 if—
                (i) the data to support  other uses of the pesticide
            on a food are being provided;
                (ii) the registrant, in submitting a request for such
            an extension provides a  schedule, including  interim
            dates to measure  progress, to assure that the data pro-
            duction will be completed before the  expiration of the
            extension period;
                (iii) the Administrator  has determined that such
            extension will not significantly delay the Administra-
            tor's schedule for  issuing a reregistration eligibility de-
            termination required under this section; and

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Sec. 4	FIFRA	44

                (iv) the Administrator has determined that based
            on  existing data, such  extension would  not signifi-
            cantly increase the risk of any unreasonable adverse
            effect  on  the  environment.1 If  the Administrator
            grants an extension under this subparagraph, the Ad-
            ministrator shall monitor the  development of the data
            and shall ensure  that the registrant is meeting the
            schedule for the production of the data.  If the Admin-
            istrator determines that the registrant is not meeting
            or has not met the schedule for the production of such
            data, the Administrator  may proceed in accordance
            with clause (iv) of section 3(c)(2)(B) or other provisions
            of this section, as appropriate, regarding the continued
            registration of the affected products  with  the minor
            use and shall inform  the public of such action. Not-
            withstanding the provisions of this subparagraph, the
            Administrator may take action to modify or revoke the
            extension under this  subparagraph if  the  Adminis-
            trator determines that the extension for the minor use
            may cause an unreasonable adverse effect on the envi-
            ronment.  In such circumstance,  the Administrator
            shall provide written notice to the registrant  revoking
            the extension of time for  submission of data.  Such
            data shall instead be due in accordance  with the date
            then established by the Administrator for submission
            of the data.
        (3) CANCELLATION.—
            (A)  If the registrant of a pesticide fails  to submit the
        information required by paragraph (1) within the time pre-
        scribed  by paragraph (2), the Administrator, by order and
        without hearing, shall cancel  the registration of such pes-
        ticide. If the registrant does not commit to support a spe-
        cific minor use of the pesticide, but is supporting and pro-
        viding data in a timely and  adequate fashion to support
        uses of the pesticide on a food, or if all uses of the  pes-
        ticide are nonfood uses and the registrant does not commit
        to support a specific minor use of the  pesticide but is sup-
        porting and providing data in a timely and adequate fash-
        ion  to support other nonfood uses of the pesticide, the Ad-
        ministrator, at the written request of the registrant, shall
        not take any  action  pursuant to this  subparagraph in re-
        gard to such unsupported  minor use until the final dead-
        line established as of the  date of enactment of the Food
        Quality Protection Act of 1996, for the submission of data
        under this section for the supported uses identified pursu-
        ant to this  subparagraph unless the Administrator deter-
        mines that the absence of the data is significant enough to
        cause human health or environmental concerns.  On the
        basis  of such determination, the Administrator may refuse
        the request for extension  by  the  registrant. Upon receipt
        of the request from the registrant, the Administrator shall
  'Indentation of the following sentences of this subparagraph is so in original (as added by
sec. 201(cX2) of P.L. 104-170). Probably should be indented the same  as flush matter of this
subparagraph.

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45	FIFRA	Sec. 4

        publish in the Federal Register a notice of the receipt of
        the request and the effective date upon which the uses not
        being supported will be voluntarily deleted from the reg-
        istration pursuant to section 6(f)(l). If the Administrator
        grants an extension under this subparagraph, the Admin-
        istrator shall monitor the development of the data  for the
        uses being supported and shall ensure that the registrant
        is meeting the schedule for the production  of such data. If
        the Administrator determines  that the registrant is not
        meeting or has not met the schedule for the production of
        such data, the Administrator may proceed in  accordance
        with section 3(c)(2)(B)(iv) regarding the continued registra-
        tion of the affected products  with the minor and other uses
        and shall inform the public of such action in  accordance
        with section 6(f)(2).  Notwithstanding  this  subparagraph,
        the Administrator may deny, modify,  or revoke the  tem-
        porary extension under this subparagraph  if the Adminis-
        trator  determines  that the continuation of the minor use
        may cause an unreasonable adverse effect  on the environ-
        ment.  In the event of modification or  revocation, the Ad-
        ministrator  shall provide, in writing,  to the registrant  a
        notice  revoking the temporary extension and  establish  a
        new effective date by which  the minor use shall be  deleted
        from the registration.
            (B)(i) If  the registrant of a pesticide submits the infor-
        mation required by  paragraph  (1) within the time pre-
        scribed by paragraph (2) and such information does not
        conform to the guidelines for submissions established by
        the Administrator,  the Administrator shall   determine
        whether the registrant made a good faith  attempt  to con-
        form its submission to such guidelines.
            (ii) If the Administrator determines that the registrant
        made a good faith attempt to conform its submission to
        such guidelines, the  Administrator shall provide the reg-
        istrant a reasonable period of time to make any necessary
        changes or corrections.
            (iii)(I) If the Administrator determines that the reg-
        istrant did not make a good faith attempt to conform its
        submission  to  such guidelines,  the  Administrator  may
        issue a notice of intent to cancel the registration.  Such  a
        notice shall be sent to the registrant by certified mail.
            (II) The  registration shall be canceled without a hear-
        ing or further notice at the end of 30 days  after receipt by
        the registrant of the notice  unless during  that time a re-
        quest for a hearing is made by the  registrant.
            (Ill) If a hearing is requested, a hearing shall be con-
        ducted under section 6(d), except that  the  only matter for
        resolution at the hearing shall be whether the registrant
        made a good faith attempt to  conform its submission to
        such guidelines. The hearing shall be  held and a deter-
        mination made within 75 days after receipt of a request for
        hearing.
        (4) GUIDELINES.—

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Sec. 4	FIFRA	46

            (A) Not later than 1 year after the effective date of
        this section, the Administrator, by order, shall issue guide-
        lines to be followed by registrants in—
                (i) summarizing studies;
                (ii) reformatting studies;
                (iii) identifying adverse information; and
                (iv) identifying studies that have been submitted
            previously that may not meet the requirements of sec-
            tion 3 or regulations issued under such section,
        under paragraph (1).
            (B) Guidelines  issued under  subparagraph  (A)  shall
        not be  subject to judicial review.
        (5)  MONITORING.—The  Administrator  shall monitor the
    progress of registrants  in  acquiring and submitting the data
    required under paragraph (1).
    (f) PHASE FOUR.—
        (1)  INDEPENDENT  REVIEW AND IDENTIFICATION  OF  OUT-
    STANDING DATA REQUIREMENTS.—
            (A) The Administrator shall review the submissions of
        all registrants of pesticides containing a particular  active
        ingredient under subsections (d)(3) and (e)(l) to determine
        if such submissions identified all the data that  are missing
        or inadequate for such  active ingredient. To  assist the re-
        view of the Administrator under this subparagraph, the
        Administrator may  require a registrant seeking reregistra-
        tion  to submit complete copies  of studies  summarized
        under subsection (e)(l).
            (B) The Administrator  shall  independently identify
        and publish in the  Federal  Register the outstanding data
        requirements  for  each active ingredient that  is  listed
        under subparagraph (B), (C), or (D) of subsection (c)(2) and
        that is contained in a  pesticide  to be reregistered  under
        this  section. The Administrator, at the same time, shall
        issue a notice under section 3(c)(2)(B) for the submission
        of the  additional data that  are required to meet such re-
        quirements.
        (2) TIME PERIODS.—
            (A) The Administrator shall take the action required
        by paragraph (1)—
                (i) in the case  of a pesticide containing an active
            ingredient listed under subsection (c)(2)(B), not later
            than 18 months after the date of the listing of such ac-
            tive ingredient;
                (ii)  in the case of a pesticide containing an active
            ingredient listed under subsection (c)(2)(C), not later
            than 24 months after the date of the listing of such ac-
            tive ingredient; and
                (iii) in the  case of a pesticide containing an active
            ingredient listed under subsection (c)(2)(D), not later
            than 33 months after the date of the listing of such ac-
            tive ingredient.
            (B) If the Administrator issues a notice to  a registrant
        under  paragraph (1)(B) for  the  submission of additional
        data, the registrant shall submit such data within  a rea-

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47	FIFRA	Sec. 4

        sonable period of time, as  determined  by the Adminis-
        trator, but not to exceed 48 months after the issuance of
        such notice.  The Administrator, on application of a reg-
        istrant, may  extend the period prescribed by the preceding
        sentence by  no more than  2 years if extraordinary  cir-
        cumstances beyond the  control of the registrant  prevent
        the registrant from submitting data within such prescribed
        period. Upon application of a registrant, the Administrator
        shall, in the  case of a minor use, extend the deadline for
        the production of residue  chemistry data under this sub-
        paragraph for data required solely  to  support that minor
        use until the final deadline  for submission of data under
        this section for the other uses of the pesticide established
        as of the date of enactment of the Food Quality Protection
        Act of 1996 if—
                (i) the data  to support other uses of the pesticide
            on a food are being provided;
                (ii) the registrant, in submitting a request  for such
            an  extension provides a schedule, including  interim
            dates to measure progress, to assure that the data pro-
            duction will be completed before the expiration of the
            extension period;
                (iii)  the  Administrator has determined  that such
            extension will not significantly delay the Administra-
            tor's schedule for issuing a reregistration eligibility de-
            termination required under this section; and
                (iv) the Administrator has  determined that based
            on  existing  data, such  extension would not signifi-
            cantly increase the  risk of any unreasonable  adverse
            effect  on  the environment.1  If  the Administrator
            grants an extension under this  subparagraph, the  Ad-
            ministrator shall monitor the development of the data
            and shall ensure that the registrant  is meeting  the
            schedule for  the production of the  data. If the Admin-
            istrator determines that the registrant is not  meeting
            or has not met the schedule for the production of such
            data, the Administrator may  proceed in  accordance
            with clause (iv) of section 3(c)(2)(B) or other provisions
            of this section, as appropriate, regarding the continued
            registration of the affected  products with the minor
            use and  shall inform  the public of  such action. Not-
            withstanding the provisions  of this subparagraph, the
            Administrator may take  action to modify or revoke the
            extension under this  subparagraph if the Adminis-
            trator determines that the extension for the minor use
            may cause an unreasonable adverse effect on the envi-
            ronment. In  such  circumstance,  the Administrator
            shall provide written notice to the registrant revoking
            the extension of time for submission of data. Such
            data shall instead be due in accordance with the date
  1 Indentation of the following sentences of this subparagraph is so in original (as added by
sec. 201(cX2) of P.L. 104-170). Probably should be indented the same as flush matter of this
subparagraph.

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Sec. 4	FIFRA	48

            then established by the Administrator for submission
            of the data.
        (3) SUSPENSIONS AND PENALTIES.—The Administrator shall
    issue  a  notice of intent to suspend the registration of a pes-
    ticide in accordance with the procedures prescribed by section
    3(c)(2)(B)(iv) if the Administrator determines that (A) tests nec-
    essary to  fill an  outstanding  data requirement for such pes-
    ticide have not been initiated within 1 year after the issuance
    of a notice under paragraph (1)(B), or (B) progress is insuffi-
    cient to  ensure submission of the data referred to in clause (A)
    within the time period prescribed by paragraph (2)(B) or the
    required data have not been  submitted  to the  Administrator
    within such time period. If the registrant does  not commit to
    support  a  specific minor use of the pesticide,  but is supporting
    and providing data in a timely and adequate fashion to support
    uses of  the pesticide on a food, or if all uses of the pesticide
    are  nonfood uses and the registrant does not commit to support
    a specific minor use of the pesticide but is supporting and pro-
    viding data in a timely and  adequate fashion to support other
    nonfood  uses of the pesticide, the Administrator, at the written
    request  of the registrant, shall not take any action pursuant to
    this paragraph in regard to  such unsupported minor use until
    the  final deadline established as of the  date of enactment of
    the  Food Quality Protection  Act of 1996,  for the submission of
    data under this section for the supported uses identified pursu-
    ant  to this paragraph unless the Administrator  determines
    that the absence of the data is  significant  enough to  cause
    human  health  or environmental  concerns. On  such a  deter-
    mination the Administrator  may refuse the request for exten-
    sion by  the registrant. Upon  receipt of the  request from the
    registrant, the Administrator shall publish in the Federal Reg-
    ister a notice of the receipt of the request  and the effective date
    upon  which the uses not  being supported will  be voluntarily
    deleted from the registration pursuant to  section 6(f)(l).  If the
    Administrator grants an extension under this paragraph, the
    Administrator shall monitor the development of the data for
    the  uses being supported and shall ensure that the registrant
    is meeting the schedule for the production of such data.  If the
    Administrator determines  that the registrant is not meeting or
    has  not  met the schedule  for the production  of such data, the
    Administrator  may  proceed  in  accordance  with  section
    3(c)(2)(B)(iv)  regarding the  continued registration of the af-
    fected products with the minor and other uses and shall inform
    the  public  of such action in accordance with section 6(f)(2). Not-
    withstanding this subparagraph, the Administrator may deny,
    modify,  or revoke the temporary  extension  under this  para-
    graph if the Administrator determines that the continuation of
    the  minor  use may cause an  unreasonable adverse effect on the
    environment. In the event of modification or revocation, the
    Administrator shall provide, in writing, to the registrant a no-
    tice  revoking the temporary extension and establish a new ef-
    fective date by which the  minor use shall be deleted from the
    registration.
    (g) PHASE FIVE.—

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49	FIFRA	Sec. 4

        (1) DATA REVIEW.—The Administrator shall conduct a thor-
    ough examination of all data submitted under this section con-
    cerning an active ingredient listed under subsection (c)(2) and
    of all other available data found by the Administrator to be rel-
    evant.
        (2) REREGISTRATION AND OTHER ACTIONS.—
            (A) Within  1 year after the submission of all data con-
        cerning an  active ingredient of a pesticide  under  sub-
        section (f), the Administrator shall determine whether pes-
        ticides containing such active ingredient are eligible for re-
        registration. For extraordinary circumstances, the Admin-
        istrator may extend such period  for not more than 1 addi-
        tional year.
            (B) Before reregistering a pesticide, the Administrator
        shall  obtain any needed  product-specific  data  regarding
        the pesticide by use of section 3(c)(2)(B) and shall review
        such data within 90 days after its submission.  The Admin-
        istrator shall require that data  under this subparagraph
        be submitted to the Administrator not later than 8 months
        after a determination of eligibility under subparagraph (A)
        has been made for each active ingredient of the pesticide,
        unless the Administrator determines that  a longer period
        is required for the generation of the data.
            (C) After conducting the review required by paragraph
        (1) for each  active ingredient of a pesticide and the review
        required by  subparagraph (B) of this paragraph, the Ad-
        ministrator  shall determine whether  to  reregister a pes-
        ticide by determining whether such pesticide meets the re-
        quirements  of section 3(c)(5). If the Administrator deter-
        mines that a pesticide is eligible to be reregistered, the Ad-
        ministrator shall reregister such  pesticide within 6 months
        after the submission of the data  concerning such pesticide
        under subparagraph (B).
            (D) If after conducting a review under paragraph (1)
        or  subparagraph (B) of this paragraph the Administrator
        determines that a pesticide should not be reregistered, the
        Administrator shall take appropriate regulatory action.
            (E) As soon as the Administrator has  sufficient infor-
        mation with respect to the dietary risk of a particular ac-
        tive ingredient, but in any event no later than the time the
        Administrator makes a determination under subparagraph
        (C) or (D) with respect to pesticides containing a particular
        active ingredient, the Administrator shall—
               (i) reassess each associated tolerance  and exemp-
            tion from the requirement for a tolerance issued under
            section  408 of the Federal Food, Drug, and Cosmetic
            Act (21 U.S.C. 346a);
               (ii)  determine whether such tolerance or exemp-
            tion meets the requirements of that Act;
               (iii)  determine whether additional tolerances or
            exemptions  should be issued;
               (iv)  publish in the Federal Register a notice set-
            ting forth  the determinations made under this  sub-
            paragraph; and

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Sec. 4	FIFRA	50

                (v)  commence promptly such  proceedings  under
            this Act and section 408 of the Federal Food, Drug,
            and Cosmetic Act as are warranted by such  deter-
            minations.
    (h) COMPENSATION OF DATA SUBMITTER.—If data that are sub-
mitted by a registrant under subsection (d), (e), (f), or (g) are used
to support the application of another person under section  3, the
registrant who submitted such data shall be entitled to compensa-
tion for the use of such data as prescribed by section 3(c)(l)(D). In
determining the amount of such compensation, the fees paid  by the
registrant under this section shall be taken into account.
    (i) FEES.—
        (1)  INITIAL FEE FOR  FOOD OR FEED USE PESTICIDE ACTIVE
    INGREDIENTS.—The registrants of pesticides that contain an ac-
    tive ingredient that is listed under subparagraph (B), (C), or
    (D) of subsection (c)(2) and that is an active ingredient  of any
    pesticide registered for a major food or feed use shall  collec-
    tively pay a fee  of $50,000 on submission of information under
    paragraphs (2) and (3) of subsection (d)  for such ingredient.
        (2)  FINAL FEE FOR FOOD OR  FEED USE PESTICIDE ACTIVE
    INGREDIENTS.—
            (A) The registrants of pesticides that contain an active
        ingredient that is listed  under subparagraph (B), (C), or
        (D) of subsection (c)(2) and that is an active ingredient of
        any pesticide  registered  for a major food or feed use shall
        collectively pay a fee of $100,000—
                (i) on submission of information for such ingredi-
            ent under subsection (e)(l) if data are reformatted
            under subsection (e)(l)(C); or
                (ii)  on  submission of  data for such  ingredient
            under subsection (e)(2)(B) if data are not reformatted
            under subsection (e)(l)(C).
            (B) The registrants of pesticides that contain an active
        ingredient that is listed under subsection (c)(2)(A) and that
        is an active ingredient  of any pesticide registered for a
        major food  or feed  use shall collectively pay a  fee of
        $150,000 at such time  as the Administrator shall  pre-
        scribe.
        (3)  FEES FOR OTHER PESTICIDE ACTIVE INGREDIENTS.—
            (A) The registrants of pesticides that contain an active
        ingredient that is listed under subparagraph (B), (C), or
        (D) of subsection (c)(2) and that is not an active ingredient
        of any pesticide registered for a major  food or  feed use
        shall  collectively pay fees in amounts determined by the
        Administrator. Such fees may not be less than one-half of,
        nor greater than, the fees required by paragraphs (1) and
        (2). A registrant shall  pay such  fees at the  times cor-
        responding  to the times  fees  prescribed by paragraphs (1)
        and (2) are to be paid.
            (B) The registrants of pesticides that contain an active
        ingredient that is listed under subsection (c)(2)(A) and that
        is not an active ingredient of any pesticide that is reg-
        istered for a major food or feed use shall collectively pay

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51	FIFRA	Sec. 4

        a fee of not more than $100,000 and not less than $50,000
        at such time as the Administrator shall prescribe.
        (4) REDUCTION OR WAIVER OF  FEES FOR  MINOR  USE AND
    OTHER PESTICIDES.—
            (A) An active ingredient that is contained only in pes-
        ticides that are registered solely for agricultural or non-
        agricultural minor uses, or a pesticide the value or volume
        of use of which is small, shall be exempt from the fees pre-
        scribed by paragraph (3).
            (B) The Administrator shall exempt any public health
        pesticide from  the payment  of the fee prescribed  under
        paragraph  (3)  if,  in  consultation with the Secretary of
        Health  and  Human  Services, the  Administrator  deter-
        mines, based on information  supplied  by the registrant,
        that the economic return to the registrant  from sales of the
        pesticide does not support the registration or reregistration
        of the pesticide.
            (C) An antimicrobial active ingredient, the production
        level of which does not  exceed  1,000,000 pounds  per year,
        shall be exempt from  the fees prescribed by paragraph (3).
        For purposes of this subparagraph, the term "antimicrobial
        active ingredient" means any active ingredient that is con-
        tained only in  pesticides that  are  not  registered for any
        food or feed use and that are—
                (i) sanitizers intended to reduce the number of liv-
            ing bacteria or viable virus particles on inanimate sur-
            face or in water or air;
                (ii) bacteriostats intended to inhibit the growth of
            bacteria in the presence of moisture;
                (iii) disinfectants intended  to destroy  or irrevers-
            ibly inactivate bacteria, fungi,  or viruses  on surfaces
            or inanimate objects;
                (iv) sterilizers intended to destroy viruses and all
            living bacteria, fungi, and their spores  on inanimate
            surfaces; or
                (v) fungicides or fungistats.
            (D)(i) Notwithstanding any other provision of this sub-
        section, in the case of a small business registrant of a pes-
        ticide,  the registrant  shall pay a fee for the reregistration
        of each active ingredient of the pesticide that does not ex-
        ceed an amount determined in accordance  with  this sub-
        paragraph.
            (ii) If during the  3-year period prior  to reregistration
        the average annual gross revenue  of the registrant from
        pesticides containing such active ingredient is—
                (I) less than  $5,000,000, the registrant  shall pay
            0.5 percent of such revenue;
                (II) $5,000,000 or more but less than $10,000,000,
            the registrant shall pay 1 percent of  such revenue; or
                (III)  $10,000,000 or more, the registrant  shall pay
            1.5 percent  of  such revenue, but  not  more  than
            $150,000.

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Sec. 4	FIFRA	52

            (iii) For the  purpose  of this subparagraph, a  small
        business registrant is a corporation, partnership, or unin-
        corporated business that—
                (I) has 150 or fewer employees; and
                (II) during the 3-year period prior to reregistra-
            tion,  had  an average annual  gross  revenue from
            chemicals that did not exceed $40,000,000.
        (5) MAINTENANCE FEE.—
            (A) Subject to other provisions of this paragraph, each
        registrant of a pesticide shall pay an annual fee by Janu-
        ary 15 of each year of—
                (i) $650 for the first registration; and
                (ii) $1,300 for each additional registration, except
            that no fee shall be charged for more than  200 reg-
            istrations held by any registrant.
            (B) In the case of a pesticide that is registered for a
        minor agricultural use, the Administrator  may reduce or
        waive the  payment of the fee imposed under this  para-
        graph if the Administrator determines  that the fee would
        significantly reduce the  availability of the pesticide for the
        use.
            (C)(i)1 The amount of each fee prescribed under sub-
        paragraph (A) shall be adjusted by the  Administrator to a
        level that will result in the collection under this paragraph
        of,  to the  extent practicable,  an aggregate  amount of
        $14,000,000 each fiscal year.
            (ii)1 in2 each of the fiscal years 1998, 1999, and 2000,
        the Administrator is authorized to collect up to  an addi-
        tional $2,000,000 in a manner consistent with subsection
        (k)(5) and the recommendations of the Inspector General of
        the Environmental Protection Agency. The total fees that
        may  be collected under  this  clause  shall  not exceed
        $6,000,000.
            (D) The maximum annual fee payable under this para-
        graph by—
                (i) a registrant holding not more than 50  pesticide
            registrations shall be $55,000; and
                (ii) a registrant holding over 50 registrations shall
            be $95,000.
            (E)(i) For a small business, the maximum annual fee
        payable under this paragraph by—
                (I) a registrant holding not more than 50  pesticide
            registrations shall be $38,500; and
                (II) a registrant holding over  50 pesticide registra-
            tions shall be $66,500.
            (ii) For purposes  of clause (i), the term "small busi-
        ness" means a corporation, partnership, or unincorporated
        business that—
                (I) has 150 or fewer employees;  and
  1Sec. 501(aX2) of P.L. 104-170 amended para. (5XC) of sec. 4(i) (7 U.S.C. 136a-l(i)) by insert-
ing "(i)" after "(CT and adding clause (ii), without specifying the Act that was being amended.
The amendments were executed to this Act to effectuate the probable intent of Congress.
  2 So in original (as added by sec. 501(aX2) of P.L. 104-170). Probably should be "In".

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53	FIFRA	Sec. 4

                (II) during the 3-year period prior to the most re-
            cent maintenance fee billing cycle, had an average an-
            nual gross revenue from chemicals that did not exceed
            $40,000,000.
            (F) The Administrator shall exempt any public health
        pesticide  from the payment  of the fee prescribed  under
        paragraph (3) if, in  consultation  with the  Secretary  of
        Health and Humans1 Services, the Administrator  deter-
        mines,  based on  information  supplied by the registrant,
        that the economic return to the registrant from sales of the
        pesticide does not support the registration or reregistration
        of the pesticide.
            (G) If any fee prescribed  by this  paragraph with re-
        spect to the registration of a pesticide is not paid by a reg-
        istrant by the time prescribed, the Administrator, by order
        and without hearing, may cancel the registration.
            (H) The authority provided under this paragraph shall
        terminate on September 30, 2001.2
        (6)  OTHER FEES.—During the period beginning on the date
    of enactment of this section and ending  on September 30,
    2001,*  the Administrator may not levy any other fees for the
    registration of a pesticide under this Act except as provided in
    paragraphs (1) through (5).
        (7)  APPORTIONMENT.—
            (A) If two or more registrants are required to pay any
        fee  prescribed by  paragraph (1), (2), or (3) with respect to
        a particular active ingredient, the fees for such  active in-
        gredient shall  be apportioned among such registrants on
        the basis  of the market share in United States sales of the
        active ingredient  for  the 3 calendar years preceding the
        date of payment of such fee, except that—
                (i) small business registrants that produce the ac-
            tive ingredient shall pay fees in accordance with para-
            graph (4)(C); and
                (ii) registrants who have no market share but who
            choose to reregister a pesticide containing such active
            ingredient shall pay the lesser of—
                    (I) 15 percent of the reregistration fee; or
                    (II) a proportionate amount of such  fee based
                on the lowest percentage  market  share held by
                any registrant active in the marketplace.
            In  no event  shall  registrants who have no market
            share but who choose to reregister a pesticide contain-
            ing such active ingredient collectively pay more than
            25 percent of the total active ingredient reregistration
            fee.
            (B) The Administrator,  by order, may require any reg-
        istrant  to submit  such reports as the Administrator deter-
        mines to be  necessary to allow the  Administrator  to
        determine and apportion fees under this subsection, to de-
  lSo in original (as added by sec. 232(2) of P.L. 104-170). Probably should be "Human".
  2 Sec. 501(aXD of P.L. 104-170 amended paras. (5XH) and (6) of sec. 4(i) (7 U.S.C. 136a-l(i))
by striking "1997" and inserting "2001", without specifying the Act that was being amended.
The amendments were executed to this Act to effectuate the probable intent of Congress.

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Sec. 4	FIFRA	54

        termine the registrant's eligibility for a reduction or waiv-
        er of a fee, or  to determine the volume usage for public
        health pesticides.
            (C) If any such report is not submitted by a registrant
        after receiving notice of such report requirement, or if any
        fee prescribed by  this subsection  (other  than paragraph
        (5)) for an active ingredient is not paid by a registrant to
        the Administrator  by the time prescribed under this sub-
        section,  the Administrator,  by order and without hearing,
        may cancel each registration held  by such registrant of a
        pesticide containing the  active  ingredient with respect to
        which the fee is imposed. The Administrator shall reappor-
        tion the fee among the  remaining registrants and notify
        the registrants  that the registrants are required to pay to
        the Administrator any unpaid balance of the fee within 30
        days after receipt of such notice.
    (j) EXEMPTION OF CERTAIN  REGISTRANTS.—The requirements of
subsections (d), (e), (f), and  (i) (other than subsection (i)(5))  regard-
ing data concerning an active ingredient and fees for review of such
data shall not apply to  any person  who is  the registrant of a pes-
ticide to the extent that, under section 3(c)(2)(D), the person would
not be required to submit or cite such data to obtain an initial reg-
istration of such pesticide.
    (k) REREGISTRATION AND EXPEDITED PROCESSING FUND.—
        (1) ESTABLISHMENT.—There  shall be established  in  the
    Treasury of the  United States  a reregistration and  expedited
    processing fund  which  shall be known  as  the Reregistration
    and Expedited Processing Fund.l
        (2)2 SOURCE AND USE.—
            (A) All moneys derived from fees collected by  the  Ad-
        ministrator under  subsection (i) shall be  deposited in  the
        fund and shall be  available to the Administrator,  without
        fiscal year limitation,  specifically to offset the costs of re-
        registration  and expedited processing of the applications
        specified in paragraph (3).  Such moneys derived from fees
        may not be expended in any fiscal year to the extent such
        moneys derived from fees would exceed  money appro-
        priated for use by the  Administrator and expended in such
        year for such costs  of reregistration and expedited process-
        ing of such applications. The Administrator shall,  prior to
        expending any such moneys derived from fees—
                 (i) effective October 1, 1997, adopt specific  and
             cost accounting rules  and procedures  as approved by
             the General Accounting Office and the Inspector Gen-
             eral of the Environmental Protection Agency to ensure
             that moneys derived from fees are allocated solely to
             the costs of reregistration and expedited processing of
  iSec. 501(b) of P.L. 104-170 amended sec. 4(kXD (7 U.S.C. 136a-l(k)(l)) by inserting "which
shall be known as the Reregistration and Expedited Processing Fund", without specifying the
Act that was being amended. The amendment was executed to this Act to effectuate the prob-
able intent of Congress.
  2 Sec. 501(c) of P.L. 104-170 amended sec. 4(k)(2) (7 U.S.C. 136a-l(k)(2)) to read as provided
above, without specifying the Act that was being amended. The amendment was executed to this
Act to effectuate the probable intent of Congress.

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 55	FIFRA	Sec. 4

             the applications specified in paragraph (3) in the same
             portion as appropriated funds;
                 (ii) prohibit the use of such moneys derived from
             fees to pay for any costs other than those necessary to
             achieve reregistration and expedited processing of the
             applications  specified in paragraph (3); and
                 (iii) ensure that personnel and facility costs associ-
             ated with the functions to be carried out under this
             paragraph do not  exceed agency averages for com-
             parable personnel and facility costs.
             (B) The Administrator shall also—
                 (i) complete the review of unreviewed reregistra-
             tion studies  required to support  the reregistration eli-
             gibility decisions  scheduled for completion in accord-
             ance with subsection (1)(2); and
                 (ii) contract for such outside assistance as may be
             necessary for review of required studies, using a gen-
             erally accepted competitive process for the selection of
             vendors of such assistance.
         (3) EXPEDITED PROCESSING OF SIMILAR APPLICATIONS.—
             (A) The Administrator shall use for each of the  fiscal
         years 1997 through 2001, not more than Vi of the mainte-
         nance fees collected in such  fiscal year1 to obtain sufficient
         personnel and resources to assure the expedited processing
         and review of any application that—
                 (i) proposes the initial or amended registration of
             an  end-use pesticide that, if  registered as  proposed,
             would be  identical or substantially similar in composi-
             tion and  labeling  to a  currently-registered pesticide
             identified in the application, or  that would differ in
             composition and labeling from any such currently-reg-
             istered pesticide only in ways that would not signifi-
             cantly increase the risk of unreasonable adverse ef-
             fects on the environment;
                 (ii) proposes an amendment  to the  registration of
             a registered  pesticide that does  not require scientific
             review of  data; or
                 (iii) proposes the initial or amended registration of
             an end use  pesticide that, if  registered as  proposed,
             would be used for a public health pesticide.
             (B) Any amounts made  available under subparagraph
         (A)  shall be used  to  obtain sufficient personnel and re-
         sources  to carry  out the activities described in such  sub-
         paragraph  that are in addition to the personnel and re-
         sources  available to carry out  such activities on the date
         of enactment of this section.
  iSec. 501(d)(l) of P.L. 104-170 amended sec. 4(k)(3) (7 U.S.C. 136a-l(kX3)) by striking "for
each of the fiscal years 1992, 1993, and 1994, Yrih of the maintenance fees collected, up to 2
million each year" and inserting "for each of the fiscal years 1997 through 2001, not more than
Yi of the maintenance fees collected in such fiscal year", without specifying the Act  that was
being amended and without including a $ before "2 million". The amendment was executed to
this Act, and to strike "$2 million", to effectuate the probable intent of Congress.

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Sec. 4	FIFRA	56

            (C)1 So long as the Administrator has not  met the
        time frames specified in clause (ii) of section 3(c)(3)(B) with
        respect to any application subject to section 3(c)(3)(B) that
        was received  prior to the date of enactment of the Food
        Quality Protection Act of 1996, the Administrator shall use
        the full amount  of the fees  specified in subparagraph (A)
        for the purposes specified therein.  Once  all applications
        subject to section  3(c)(3)(B) that were received  prior  to
        such date of enactment have been acted upon, no limita-
        tion shall be imposed  by the preceding sentence of this
        subparagraph so long as the Administrator meets the time
        frames specified in clause (ii) of section 3(c)(3)(B) on 90
        percent of affected applications in a fiscal year. Should the
        Administrator not meet such time frames  in a fiscal year,
        the limitations imposed by the first sentence of this sub-
        paragraph shall  apply  until all  overdue applications sub-
        ject to section 3(c)(3)(B) have been acted upon.
        (4) UNUSED FUNDS.—Money in  the  fund not  currently
    needed to carry  out this section shall be—
            (A) maintained on hand  or on deposit;
            (B) invested in obligations  of the United States  or
        guaranteed  thereby; or
            (C) invested in  obligations, participations, or  other in-
        struments that are lawful investments for fiduciary, trust,
        or public funds.
        (5)2 ACCOUNTING AND  PERFORMANCE.—The Administrator
    shall take  all  steps necessary to  ensure that expenditures from
    fees authorized  by subsection (i)(5)(C)(ii) are used only to carry
    out the goals  established under  subsection (1). The Reregistra-
    tion and Expedited Processing Fund  shall be designated as an
    Environmental  Protection Agency component  for purposes of
    section 3515(c)  of title 31, United  States Code. The annual
    audit required under section 3521 of such title of the financial
    statements of activities under this Act under section 3515(b) of
    such title shall include an audit of the fees collected under sub-
    section (i)(5)(C) and  disbursed, of the amount appropriated to
    match such fees, and of the Administrator's attainment of per-
    formance measures and goals established under subsection (1).
    Such an audit shall also include  a review of the reasonableness
    of the  overhead allocation and adequacy of disclosures of direct
    and indirect costs associated with carrying out the reregistra-
    tion and expedited  processing of the applications  specified in
    paragraph (3), and the basis for and accuracy of all costs paid
    with moneys derived from such fees.  The Inspector General
    shall conduct the annual audit and report the findings and rec-
    ommendations  of such audit to the  Administrator and to the
    Committees on Agriculture  of  the  House of Representatives
  iSec. 501(dX2) of P.L. 104-170 added subpara. (C) to sec. 4(k)(3) (7 U.S.C. 136a-l(k)(3)), with-
out specifying the Act that was being amended. The amendment was executed to this Act to
effectuate the probable intent of Congress.
  2 Sec. 501(e) of P.L. 104-170 amended sec. 4(kX5) (7 U.S.C. 136a-l(k)(5)) to read as provided
above, without specifying the Act that was being amended. The amendment was executed to this
Act to effectuate the probable intent of Congress.

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 57	FIFRA	Sec. 4

     and the Senate. The cost of such audit shall be paid for out of
     the fees collected under subsection (i)(5)(C).
     (I)1 PERFORMANCE MEASURES AND GOAL.—The Administrator
 shall establish and publish annually in the Federal Register per-
 formance measures and  goals. Such measures and goals shall in-
 clude—
         (1)  the number of products  reregistered,  canceled,  or
     amended, the status of reregistration, the number and type of
     data requests under section 3(c)(2)(B) issued to support product
     reregistration by active ingredient, the progress  in reducing
     the number of unreviewed, required reregistration studies, the
     aggregate status of tolerances  reassessed, and the number of
     applications for registration submitted under subsection  (k)(3)
     that were approved or disapproved;
         (2) the future schedule for reregistrations, including the
     projection for such schedules that will be  issued under sub-
     section (g)(2)(A) and  (B) in the  current fiscal year and the suc-
     ceeding fiscal year; and
         (3) the projected year  of completion of the reregistrations
     under this section.
     (m) JUDICIAL REVIEW.—Any failure  of the Administrator to
 take any action required by this section shall be subject to judicial
 review  under the procedures prescribed  by section 16(b).
     (n) AUTHORIZATION OF  FUNDS To DEVELOP PUBLIC HEALTH
 DATA.—
        (1) DEFINITION.—For  the purposes of  this  section,  "Sec-
     retary" means  the Secretary of Health and Human Services,
     acting through the Public Health Service.
        (2) CONSULTATION.—In the case  of a pesticide registered
     for use in public health programs for vector control or for  other
     uses the Administrator determines  to be human health protec-
     tion uses, the Administrator shall,  upon timely request by the
     registrant or any other interested person,  or on the Adminis-
     trator's own initiative may, consult with the Secretary prior to
     taking  final  action  to suspend  registration  under  section
     3(c)(2)(B)(iv), or cancel a registration under  section 4, 6(e), or
     6(f). In consultation  with the Secretary,  the Administrator
     shall prescribe the form and content of requests under this sec-
     tion.
        (3) BENEFITS  TO SUPPORT FAMILY.—The  Administrator,
     after consulting with the  Secretary, shall make a determina-
     tion whether the potential benefits of continued use of the pes-
     ticide for  public health or health  protection purposes are of
     such significance as to warrant  a commitment by the Secretary
     to conduct or to arrange for the conduct of the studies required
     by  the Administrator to support continued  registration under
     section 3 or reregistration under section 4.
        (4) ADDITIONAL  TIME.—If  the  Administrator  determines
    that such a commitment is warranted and in the public inter-
     est, the Administrator shall notify the Secretary and shall, to
  1Sec. 501(f) of P.L. 104-170 amended sec. 4 (7 U.S.C. 136a-l) by redesignating subsecs. (1)
and (m) aa subsecs. (m) and (n), respectively, and inserting a new subsec. (1), without specifying
the Act that was being amended. The amendments were executed to this Act to effectuate the
probable intent of Congress.

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Sec. 5	FIFRA	58

    the extent necessary,  amend a notice issued under  section
    3(c)(2)(B) to specify additional reasonable time periods for sub-
    mission of the data.
        (5) ARRANGEMENTS.—The Secretary  shall make such ar-
    rangements for the  conduct  of required studies as the Sec-
    retary finds necessary and appropriate to permit submission of
    data in accordance with the time periods prescribed by the Ad-
    ministrator. Such arrangements  may include Public  Health
    Service intramural research activities, grants, contracts, or co-
    operative agreements with academic, public health, or other or-
    ganizations qualified by experience and training to conduct
    such studies.
        (6) SUPPORT.—The Secretary may provide for support of
    the required studies using funds authorized to be appropriated
    under this section, the Public Health Service Act, or other ap-
    propriate  authorities. After  a determination is made  under
    subsection  (d), the Secretary shall notify the Committees on
    Appropriations of the House of Representatives and the Senate
    of the sums required  to conduct the necessary studies.
        (7) AUTHORIZATION OF APPROPRIATIONS.—There is author-
    ized to be appropriated to carry out the purposes of this section
    $12,000,000 for fiscal year 1997, and such sums as may be nec-
    essary for succeeding fiscal years.
SEC. 5. [136c] EXPERIMENTAL USE PERMITS.
    (a) ISSUANCE.—Any person may apply to the Administrator for
an experimental use permit for a pesticide. The  Administrator shall
review the application. After completion of the review, but not later
than one hundred and twenty days after receipt of the application
and all required  supporting data, the Administrator shall either
issue  the permit or notify the applicant of the  Administrator's de-
termination not to issue  the permit and the reasons therefor. The
applicant may  correct the application or  request a  waiver of the
conditions for such permit within thirty days of receipt by the ap-
plicant of such notification. The Administrator may issue an experi-
mental  use permit only  if the Administrator determines that the
applicant needs such permit in  order to accumulate  information
necessary to register a pesticide under section 3 of this Act. An ap-
plication for an experimental use permit may be filed at  any time.
    (b)  TEMPORARY TOLERANCE LEVEL.—If the Administrator de-
termines that the use of  a pesticide may reasonably be expected to
result in any residue  on  or in food or feed, the Administrator may
establish a temporary tolerance  level for the  residue of the pes-
ticide before issuing the experimental use permit.
    (c) USE UNDER PERMIT.—Use of  a pesticide under an experi-
mental  use permit shall  be under the supervision of the Adminis-
trator, and shall be subject to such terms and conditions and be for
such period of time as the Administrator may prescribe in the per-
mit.
    (d)  STUDIES.—When  any experimental use  permit is issued for
a pesticide containing any chemical  or combination of  chemicals
which has not been included in any previously registered pesticide,
the Administrator may specify that studies be  conducted to detect
whether the  use  of the pesticide  under the permit may  cause un-

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59	FIFRA	Sec. 6

reasonable adverse effects on the environment. All results of such
studies shall be reported to the Administrator before such pesticide
may be registered under section 3.
    (e) REVOCATION.—The  Administrator may  revoke any experi-
mental use permit, at any time,  if the Administrator finds that its
terms or conditions are being violated, or that its terms and condi-
tions are inadequate to avoid unreasonable adverse effects on the
environment.
    (f)  STATE  ISSUANCE OF PERMITS.—Notwithstanding  the  fore-
going provisions of this section, the Administrator shall, under
such  terms and conditions as the Administrator may by regulations
prescribe, authorize any State to issue an experimental use permit
for a pesticide. All provisions of section  11 relating to State plans
shall apply with equal force to a State plan for the issuance  of ex-
perimental use permits under this section.
    (g) EXEMPTION FOR AGRICULTURAL RESEARCH AGENCIES.—Not-
withstanding the foregoing provisions of  this section, the  Adminis-
trator may issue an experimental use permit for a pesticide to any
public or private agricultural research agency or educational insti-
tution which applies for such permit.  Each permit shall not exceed
more than a one-year period or such other specific time as the Ad-
ministrator may prescribe. Such  permit shall be issued under such
terms and conditions restricting the use of the pesticide as the Ad-
ministrator may require. Such pesticide may be used only by such
research agency or educational institution for purposes of experi-
mentation.
SEC. 6. [136d] ADMINISTRATIVE REVIEW; SUSPENSION.
    (a) EXISTING STOCKS AND  INFORMATION.—1
        (1) EXISTING STOCKS.—The Administrator may permit the
    continued  sale and use of existing stocks of a pesticide whose
    registration is suspended  or canceled under this section, or sec-
    tion 3 or 4, to such extent, under such conditions, and for such
    uses as the Administrator determines that such sale  or use is
    not inconsistent with the purposes of this Act.
        (2) INFORMATION.—If at  any time after the registration of
    a pesticide the registrant  has additional factual information re-
    garding unreasonable  adverse effects  on the environment of
    the pesticide, the registrant shall submit such information to
    the Administrator.
    (b) CANCELLATION AND CHANGE IN CLASSIFICATION.—If it ap-
pears to the Administrator  that a pesticide or its labeling or other
material required to be submitted does not comply with the provi-
sions of this Act or, when used in accordance with widespread  and
commonly  recognized  practice, generally causes unreasonable ad-
verse effects on  the environment,  the Administrator may issue a
notice of the Administrator's intent either—
        (1) to cancel its registration or to change its classification
    together with the reasons (including the factual basis) for the
    Administrator's action, or
  'Sec. 106(aXD of P.L. 104-170 amended subsec. (a) by striking the heading and inserting "(a)
EXISTING STOCKS AND INFORMATION.—". The second subsec. designation for "(a)" was omitted
to effectuate the probable intent of Congress.

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Sec. 6	FIFRA	60

        (2) to hold a hearing to determine whether or not its reg-
    istration should be canceled or its classification changed.
Such notice shall be sent to the registrant and made public. In de-
termining whether to issue any  such notice, the Administrator
shall include among those factors to be taken into account the im-
pact of the action proposed in such notice on production and prices
of agricultural commodities, retail food prices, and otherwise on the
agricultural economy. At least 60 days prior to sending such notice
to the  registrant or  making public such notice, whichever occurs
first, the Administrator shall provide the Secretary of Agriculture
with a copy of such notice and an analysis of such impact on the
agricultural economy. If the Secretary comments in writing to the
Administrator regarding the notice  and analysis within 30  days
after receiving them, the  Administrator shall publish in the  Fed-
eral Register (with the notice) the comments of the Secretary and
the response of the Administrator with regard to the Secretary's
comments. If the Secretary does not comment in writing to the Ad-
ministrator regarding the  notice and analysis within 30 days  after
receiving them, the Administrator may notify the registrant and
make public the notice at any time after such 30-day period not-
withstanding the foregoing 60-day time requirement.  The time re-
quirements imposed  by the preceding 3 sentences may be waived
or modified to the extent agreed upon by the Administrator and the
Secretary. Notwithstanding any other provision of this subsection
(b)  and section  25(d), in the event that the Administrator deter-
mines that  suspension  of a pesticide registration is  necessary to
prevent an imminent hazard to human health, then upon such a
finding the Administrator may waive the requirement of notice to
and consultation with the  Secretary of Agriculture pursuant to sub-
section (b) and of submission to the  Scientific Advisory Panel pur-
suant to section 25(d) and  proceed in accordance with subsection
(c). When a public health use is  affected, the Secretary  of Health
and Human Services should provide available benefits and use in-
formation,  or an analysis thereof, in accordance with the proce-
dures followed and subject to the same conditions as the Secretary
of Agriculture in the case  of agricultural pesticides. The proposed
action shall become final and  effective at the end of 30  days  from
receipt by the registrant,  or publication, of a notice  issued under
paragraph (1), whichever  occurs later, unless within  that time ei-
ther (i) the registrant makes the necessary corrections, if possible,
or (ii) a request for  a hearing is  made by a person  adversely  af-
fected by  the notice.  In the event a hearing is held pursuant to
such a request or to the Administrator's determination under para-
graph (2), a decision pertaining to registration or classification is-
sued after completion of such hearing shall be final. In taking any
final action under this subsection, the Administrator shall consider
restricting a pesticide's use or uses as an alternative to cancellation
and shall  fully explain the reasons for these  restrictions, and  shall
include among those factors to be  taken into account  the impact of
such final action on production and prices  of agricultural commod-
ities, retail food prices, and otherwise on the agricultural economy,
and the Administrator shall  publish in the Federal Register an
analysis of such impact.
    (c) SUSPENSION.—

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61	FIFRA	Sec. B

        (1) ORDER.—If the Administrator determines that action is
    necessary to prevent an imminent hazard during the time re-
    quired for cancellation or change in classification proceedings,
    the Administrator may, by order, suspend the registration of
    the pesticide immediately. Except as provided in paragraph (3),
    no order of suspension may be issued under this subsection un-
    less the Administrator has issued, or at the same time issues,
    a notice of intention to cancel the registration or change the
    classification  of  the pesticide under subsection (b). Except as
    provided  in paragraph (3), the Administrator shall notify the
    registrant prior  to issuing any suspension order. Such notice
    shall include  findings pertaining to the question of "imminent
    hazard". The  registrant shall then have an opportunity, in ac-
    cordance  with the provisions of paragraph (2), for an  expedited
    hearing before the Administrator  on the  question of whether
    an imminent hazard exists.
        (2) EXPEDITE HEARING.—If no request for a hearing is sub-
    mitted to the  Administrator within five days of the registrant's
    receipt of the notification provided for by paragraph (1), the
    suspension order may be issued and shall take effect and shall
    not be reviewable by a court. If a hearing is requested,  it shall
    commence within five days  of the receipt of the  request for
    such  hearing unless the registrant  and the Administrator
    agree that it shall commence at a later time. The hearing shall
    be held in accordance with the provisions of subchapter II of
    title 5 of the United States Code, except that the presiding offi-
    cer need not be a certified hearing examiner. The presiding of-
    ficer shall have  ten  days  from the conclusion of the presen-
    tation of evidence to submit recommended findings and conclu-
    sions to the Administrator, who shall then have seven days to
    render a final order on the issue of suspension.
        (3) EMERGENCY ORDER.—Whenever the  Administrator de-
    termines  that an emergency exists that does not permit the
    Administrator to hold a hearing before suspending, the Admin-
    istrator may issue a suspension order in advance of notification
    to  the registrant. The Administrator may issue an emergency
    order under this paragraph before issuing a  notice of intention
    to  cancel the registration or change the classification  of the
    pesticide under subsection (b) and the Administrator shall pro-
    ceed to issue the notice under subsection (b) within 90  days of
    issuing an emergency order. If  the Administrator  does not
    issue a notice under subsection  (b) within 90 days of  issuing
    an emergency order,  the emergency order shall expire. In the
    case of an emergency order, paragraph (2) shall apply except
    that (A) the order of suspension  shall be  in  effect pending the
    expeditious completion of the remedies provided by that para-
    graph and the issuance of a  final order on suspension, and (B)
    no party other than the registrant and the Administrator shall
    participate except that any person adversely affected may file
    briefs within  the time allotted by the Administrator's rules.
    Any person so filing briefs shall be considered a party to such
    proceeding for the purposes of section 16(b).
        (4) JUDICIAL REVIEW.—A final order on the question of sus-
    pension following a hearing  shall be  reviewable in accordance

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Sec. 6	FIFRA	62

    with Section 16 of this Act, notwithstanding the fact that any
    related cancellation proceedings have not been completed. Any
    order of suspension entered prior to a hearing before the Ad-
    ministrator shall be subject to immediate review in an action
    by the registrant or other interested person with the  concur-
    rence of the registrant in an appropriate  district court, solely
    to determine whether the order of suspension was arbitrary,
    capricious or an abuse of discretion,  or whether the order was
    issued in  accordance with the procedures established by law.
    The effect of any order of the court will be only to stay the ef-
    fectiveness of  the  suspension order, pending the Administra-
    tor's final decision with respect to cancellation or change  in
    classification.  This  action may  be maintained  simultaneously
    with any administrative review proceeding under this section.
    The commencement of proceedings under this paragraph shall
    not operate as a stay of order, unless ordered by the court.
    (d) PUBLIC HEARINGS AND SCIENTIFIC REVIEW.—In the event a
hearing is requested pursuant to subsection (b) or determined upon
by the Administrator pursuant to subsection (b), such hearing shall
be held after due  notice for the purpose of receiving  evidence rel-
evant and material to the issues raised  by the objections filed  by
the applicant or other interested parties, or to the issues stated  by
the Administrator, if the hearing is  called by  the Administrator
rather than by the filing of objections. Upon a showing of relevance
and reasonable scope of evidence sought by any party  to a public
hearing,  the Hearing Examiner shall  issue a  subpena to compel
testimony or production of documents from any person. The Hear-
ing Examiner shall be guided by the principles of the Federal Rules
of Civil Procedure in making any order for the protection of the
witness or the content of documents produced and  shall order the
payment of reasonable fees  and expenses as a  condition to requir-
ing testimony  of the witness. On contest, the subpena may be en-
forced by an appropriate United States district court in accordance
with the principles stated herein. Upon the request of any party to
a public hearing and when in the Hearing Examiner's judgment it
is necessary or desirable, the Hearing Examiner shall at any time
before the hearing record is  closed refer to a Committee of the Na-
tional Academy of Sciences the relevant  questions of scientific fact
involved in the public hearing. No member of any committee of the
National Academy of Sciences established to carry out the func-
tions of this section shall have a financial or other conflict of inter-
est with respect to any matter considered by such  committee. The
Committee of the National  Academy  of Sciences  shall report  in
writing to the  Hearing Examiner within 60 days after such referral
on these questions of scientific fact. The  report shall be made pub-
lic and shall be considered as part  of the hearing record. The Ad-
ministrator shall enter into appropriate arrangements with the Na-
tional Academy of Sciences to assure  an objective and competent
scientific review of the questions presented to Committees of the
Academy and  to provide such other scientific advisory  services  as
may be required by the Administrator for carrying out the purposes
of this Act. As soon as practicable after completion of the  hearing
(including the report  of the Academy) but not later than 90  days
thereafter, the Administrator shall evaluate the data and reports

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63	FIFRA	Sec. 6

before the Administrator and  issue an order either revoking the
Administrator's notice of intention issued pursuant to this section,
or shall issue an order either canceling the registration, changing
the classification,  denying the registration,  or requiring modifica-
tion of the labeling or packaging of the article. Such order shall be
based only on substantial evidence of record of such hearing and
shall  set  forth detailed  findings of fact upon which  the order  is
based.
    (e) CONDITIONAL REGISTRATION.—
        (1) The Administrator  shall issue a notice of intent to can-
    cel a  registration issued under section 3(c)(7) of this Act if (A)
    the Administrator, at any  time during  the period provided for
    satisfaction of any condition imposed, determines that the reg-
    istrant has failed to initiate and pursue appropriate action to-
    ward  fulfilling any condition imposed, or (B) at the end of the
    period provided for satisfaction of any condition imposed, that
    condition has not been met. The Administrator may permit the
    continued sale and use of  existing stocks of a pesticide  whose
    conditional registration has  been canceled under  this sub-
    section to such extent, under such conditions, and for such uses
    as the Administrator may specify if the Administrator deter-
    mines that such sale or use is not inconsistent with the pur-
    poses of this Act and will not have unreasonable adverse ef-
    fects on the environment.
        (2) A cancellation proposed under this subsection shall be-
    come  final and effective at the end of thirty days from receipt
    by the registrant of the notice of intent  to cancel unless during
    that time a request for hearing is made by a person adversely
    affected by the notice. If a hearing is requested, a hearing shall
    be conducted  under subsection (d) of  this  section. The only
    matters for resolution at that hearing shall be whether the reg-
    istrant has initiated and pursued appropriate action to comply
    with the condition or  conditions within the time provided  or
    whether the condition or conditions have been  satisfied within
    the time provided, and whether the Administrators  determina-
    tion with respect to the disposition of existing stocks is consist-
    ent with this Act. A decision  after completion of such hearing
    shall be final.  Notwithstanding any other provision of this sec-
    tion, a hearing shall be held and a determination made within
    seventy-five days after receipt of a request for such hearing.
    (f) GENERAL PROVISIONS.—
        (1) VOLUNTARY CANCELLATION.—
            (A) A  registrant may, at any time, request that a pes-
        ticide registration of the registrant be canceled or amended
        to terminate one or more pesticide uses.
            (B) Before acting  on  a request under subparagraph
        (A), the Administrator shall publish in the Federal Reg-
        ister a notice of the receipt of the request  and provide for
        a 30-day period in which the public  may comment.
            (C) In the case of a pesticide that is registered for a
        minor agricultural  use,  if the Administrator determines
        that the  cancellation  or  termination of uses  would ad-
        versely affect the availability  of the pesticide for use, the
        Administrator—

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Sec. 6	FIFRA	64

                (i) shall publish in the Federal Register  a  notice
            of the receipt of the request and make reasonable ef-
            forts to inform persons who so use the pesticide of the
            request; and
                (ii) may not approve or reject the request until the
            termination of the  180-day  period  beginning on the
            date of publication  of the  notice in the Federal Reg-
            ister, except that the Administrator  may  waive the
            180-day period upon the request of the registrant or if
            the Administrator determines that the continued use
            of the pesticide would pose  an unreasonable adverse
            effect on the environment.
            (D) Subject to paragraph (3)(B), after  complying with
        this  paragraph,  the Administrator may approve  or deny
        the request.
        (2) PUBLICATION OF NOTICE.—A notice of denial of registra-
    tion, intent  to cancel, suspension,  or intent to suspend issued
    under this Act or a notice issued under subsection  (c)(4) or
    (d)(5)(A)  of section 4 shall be published in the Federal  Register
    and shall be sent by certified mail, return receipt requested, to
    the registrant's or applicant's address of record on file with the
    Administrator. If the mailed notice is returned  to the Adminis-
    trator as undeliverable  at that address,  if delivery  is  refused,
    or if the Administrator otherwise is unable to accomplish deliv-
    ery of the notice to the registrant or applicant after making
    reasonable efforts to do so, the notice shall be  deemed to have
    been received by the registrant or applicant on  the date the no-
    tice was published in the Federal Register.
        (3) TRANSFER OF REGISTRATION OF PESTICIDES REGISTERED
    FOR MINOR AGRICULTURAL USES.—In the case of a pesticide that
    is registered for a minor agricultural use:
            (A)  During the 180-day period referred to in paragraph
        (l)(C)(ii), the registrant of the pesticide may notify the Ad-
        ministrator of an agreement between the registrant and a
        person or persons (including persons who  so use  the pes-
        ticide) to transfer the registration of the pesticide, in lieu
        of canceling or amending the registration to terminate the
        use.
            (B) An application for transfer of registration, in con-
        formance with  any  regulations the  Administrator  may
        adopt with respect to  the transfer of the pesticide registra-
        tions, must be submitted to the Administrator within 30
        days of the date of notification  provided pursuant to  sub-
        paragraph (A). If such an application is submitted, the Ad-
        ministrator shall approve the  transfer and shall not ap-
        prove the request for  voluntary cancellation or amendment
        to terminate use unless the Administrator  determines that
        the continued use of  the pesticide would cause an unrea-
        sonable adverse effect on the environment.
            (C) If the Administrator approves the transfer and the
        registrant transfers the registration of the pesticide, the
        Administrator shall not cancel  or amend  the registration
        to delete the use or rescind the transfer of  the registration,
        during the 180-day period beginning on the date of the ap-

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65	FIFRA	Sec. 7

        proval of the transfer unless the Administrator determines
        that the continued use of the pesticide would cause an un-
        reasonable adverse effect on the environment.
            (D) The  new registrant of the pesticide shall assume
        the outstanding data and other requirements for the pes-
        ticide that are pending at the time of the transfer.
        (4) UTILIZATION OF DATA FOR VOLUNTARILY CANCELED PES-
    TICIDE.—When an application is filed with the Administrator
    for the registration of a pesticide for a minor use  and another
    registrant subsequently voluntarily cancels its registration for
    an identical or substantially similar  pesticide for an identical
    or substantially similar use, the Administrator shall process,
    review, and evaluate the pending application  as if the vol-
    untary cancellation had not yet taken place except that the Ad-
    ministrator shall not take such action if the Administrator de-
    termines that such minor use may cause an unreasonable ad-
    verse effect on the environment. In order to rely  on this sub-
    section, the applicant must certify that it agrees to satisfy any
    outstanding data requirements necessary to support the rereg-
    istration of the pesticide  in accordance with the data submis-
    sion schedule established by the Administrator.
    (g) NOTICE FOR STORED  PESTICIDES WITH CANCELED OR SUS-
PENDED REGISTRATIONS.—
        (1) IN GENERAL.—Any producer or exporter of pesticides,
    registrant of a pesticide, applicant for registration  of a pes-
    ticide, applicant for or holder of an experimental use permit,
    commercial  applicator, or any person who distributes or sells
    any pesticide, who possesses any pesticide which has had its
    registration canceled or suspended under this section shall no-
    tify the Administrator and appropriate State and local officials
    of—
            (A) such  possession,
            (B) the quantity of such pesticide  such person pos-
        sesses, and
            (C) the place at which such pesticide is stored.
        (2) COPIES.—The Administrator  shall transmit a copy of
    each notice submitted under this subsection to the regional of-
    fice of the Environmental Protection Agency which has juris-
    diction over the place of pesticide storage identified in the no-
    tice.
    (h) JUDICIAL REVIEW.—Final orders of the Administrator under
this section shall be subject to judicial review pursuant to section
16.
SEC. 7. [136e] REGISTRATION OF ESTABLISHMENTS.
    (a) REQUIREMENT.—No person shall produce any pesticide sub-
ject to this Act or active ingredient used in producing a pesticide
subject to this Act in any State unless the establishment in which
it is produced is registered with the Administrator. The application
for registration  of any establishment  shall include  the name and
address of the establishment and of the producer who operates
such establishment.

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Sec. 7	FIFRA	66

    (b)  REGISTRATION.—Whenever the  Administrator receives  an
application under subsection (a), the Administrator shall register
the establishment and assign it an establishment number.
    (c) INFORMATION REQUIRED.—
        (1) Any  producer operating an establishment  registered
    under this section  shall inform the Administrator  within  30
    days after it is registered of the types and amounts of pes-
    ticides and, if applicable, active ingredients used in producing
    pesticides—
            (A) which the producer is currently producing;
            (B) which the producer has produced during the past
        year; and
            (C) which the producer  has sold or distributed during
        the past year.
    The information required by this paragraph shall be kept cur-
    rent and submitted to the Administrator annually as required
    under such regulations as the Administrator may prescribe.
        (2) Any such producer shall, upon the request of the Ad-
    ministrator for the  purpose  of issuing  a stop sale order pursu-
    ant to section 13, inform the Administrator of the  name and
    address of any recipient of any pesticide produced in any reg-
    istered establishment which the producer operates.
    (d)  CONFIDENTIAL RECORDS AND INFORMATION.—Any informa-
tion submitted to  the  Administrator pursuant  to subsection  (c)
other than the names of the pesticides or active ingredients used
in producing pesticides  produced, sold,  or  distributed at an  estab-
lishment shall be considered confidential and shall be subject to the
provisions of section 10.
SEC. 8. [136f] BOOKS AND RECORDS.
    (a)  REQUIREMENTS.—The Administrator may prescribe regula-
tions  requiring producers, registrants, and applicants for registra-
tion to maintain such records with respect to their operations and
the pesticides and devices  produced as the Administrator  deter-
mines are necessary  for the effective enforcement  of this Act and
to make the records available for inspection and  copying in the
same manner as provided in subsection (b).  No records required
under this subsection shall extend to financial data,  sales data
other than shipment data, pricing data, personnel data, and  re-
search data (other than data relating to registered  pesticides or to
a pesticide for which an application for registration has  been filed).
    (b)  INSPECTION.—For the purposes  of  enforcing the provisions
of this Act, any producer, distributor, carrier, dealer, or any other
person who sells or offers for sale, delivers or offers  for delivery any
pesticide or device subject to this Act,  shall,  upon request of any
officer or employee of the Environmental  Protection Agency or of
any State or political subdivision, duly designated by the Adminis-
trator, furnish or permit such  person  at  all reasonable times to
have  access to, and to  copy: (1) all records showing the delivery,
movement, or holding of such  pesticide or device, including the
quantity, the date  of shipment  and receipt, and the name  of the
consignor and consignee; or (2) in the event of the  inability  of any
person  to produce  records containing such information, all other
records  and information relating to such delivery, movement, or

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67	FIFRA	Sec. 9

holding of the pesticide or device. Any inspection with respect to
any records and information referred to in this subsection shall not
extend to financial data, sales data other than shipment data, pric-
ing data, personnel data, and research data (other than data relat-
ing to registered pesticides or to a pesticide for which an applica-
tion for registration has been filed). Before undertaking an inspec-
tion under this subsection, the officer or employee must present to
the owner,  operator,  or  agent in charge of the establishment or
other place where pesticides or devices are held for distribution or
sale, appropriate credentials and a written statement as to the rea-
son for the inspection, including a statement as to whether a viola-
tion of the law is suspected. If no violation is suspected,  an alter-
nate and sufficient  reason shall  be given in writing. Each such in-
spection shall   be  commenced  and  completed  with  reasonable
promptness.
SEC. 9. [136g] INSPECTION OF ESTABLISHMENTS, ETC.
    (a) IN GENERAL.—(1) For  purposes of enforcing the provisions
of this Act, officers or employees of the Environmental Protection
Agency  or of any State duly designated by the Administrator are
authorized to enter at reasonable times (A) any establishment or
other place where pesticides or devices are held for distribution or
sale for the purpose of inspecting and obtaining samples of any pes-
ticides or devices, packaged, labeled,  and released for shipment,
and samples of any containers or labeling for such pesticides or de-
vices, or (B) any place where there is being held any pesticide the
registration of which  has been suspended or canceled for the pur-
pose of determining compliance with section 19.
    (2) Before undertaking such inspection, the officers or employ-
ees must present to the owner, operator, or agent in charge of the
establishment or other place where pesticides  or devices are held
for distribution or sale, appropriate credentials and a written state-
ment as to the reason for the inspection, including a  statement as
to whether a violation of the law is suspected. If no violation is sus-
pected, an alternate and sufficient reason shall  be given in writing.
Each  such inspection  shall be  commenced and completed with rea-
sonable promptness. If the officer or employee obtains  any samples,
prior  to leaving the premises,  the officer or employee shall give to
the owner, operator,  or agent in charge a receipt describing the
samples obtained and, if requested, a portion of each such sample
equal in volume or weight to the portion retained. If an analysis
is made of such samples, a copy of the results of such analysis shall
be furnished promptly to the owner, operator,  or agent in charge.
    (b)  WARRANTS.—For purposes of  enforcing the provisions of
this Act and upon a showing to an officer or court of competent ju-
risdiction that there is reason to believe that the provisions of this
Act have  been  violated, officers or employees  duly designated by
the Administrator are empowered to  obtain and to execute  war-
rants authorizing—
        (1) entry, inspection, and copying of records for purposes of
    this section or section 8;
        (2) inspection and reproduction of all records showing the
    quantity, date of shipment, and the name of consignor and con-
    signee of any pesticide or device  found in the establishment

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Sec. 10	FIFRA	68

    which is adulterated, misbranded, not registered (in the case
    of a pesticide) or otherwise in violation of this Act and in the
    event of the inability of any person to produce records contain-
    ing such information, all other records and information relat-
    ing to such  delivery, movement, or holding  of the pesticide or
    device; and
       (3) the seizure of any pesticide or device which is in viola-
    tion of this Act.
    (c) ENFORCEMENT.—
       (1) CERTIFICATION OF FACTS TO ATTORNEY  GENERAL.—The
    examination of pesticides or devices shall be made in the Envi-
    ronmental  Protection Agency or  elsewhere as the Adminis-
    trator may designate for the purpose of determining from such
    examinations whether they comply with  the  requirements of
    this Act. If it shall appear from  any such examination that
    they  fail to  comply  with the requirements of this Act, the Ad-
    ministrator shall cause notice to be given to  the person against
    whom criminal or civil proceedings are contemplated. Any per-
    son so notified shall  be given an opportunity to present the
    person's views, either orally or in writing, with regard to such
    contemplated proceedings, and if in the opinion of the Adminis-
    trator it appears that the provisions of this Act have been vio-
    lated by such person, then the Administrator shall certify the
    facts to the Attorney General, with a copy of the results of the
    analysis or the examination of such pesticide for the institution
    of a  criminal proceeding pursuant to  section  14(b) or  a civil
    proceeding under section 14(a), when the  Administrator deter-
    mines that such action will be sufficient to effectuate the pur-
    poses of this Act.
       (2)  NOTICE  NOT  REQUIRED.—The  notice of contemplated
    proceedings and opportunity to present views set forth  in this
    subsection are not prerequisites to the institution of any pro-
    ceeding by the Attorney General.
       (3) WARNING NOTICES.—Nothing in this Act  shall be con-
    strued as requiring the Administrator to institute proceedings
    for prosecution of minor violations of this Act whenever the Ad-
    ministrator  believes that the public interest will be adequately
    served by a  suitable written notice of warning.
SEC. 10. [136h] PROTECTION OF TRADE SECRETS AND OTHER INFOR-
           MATION.
    (a) IN GENERAL.—In submitting data required  by this Act, the
applicant may (1) clearly mark any portions thereof which in the
applicant's opinion are trade secrets or commercial or financial in-
formation and  (2) submit such marked material separately from
other material required to be submitted under this Act.
    (b) DISCLOSURE.—Notwithstanding any other provision of this
Act and subject to the limitations  in subsections (d) and (e) of this
section, the Administrator shall not make public information which
in the Administrator's judgment contains or relates to trade secrets
or commercial or financial information obtained  from a person and
privileged or confidential, except that,  when necessary to carry out
the provisions of this Act, information  relating to formulas of prod-
ucts acquired by authorization  of this  Act  may be  revealed to any

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69	FIFRA	Sec. 10

Federal agency consulted and may be revealed at a public hearing
or in findings of fact issued by the Administrator.
    (c) DISPUTES.—If the Administrator proposes to release for in-
spection information which the applicant or registrant believes to
be  protected from disclosure under subsection (b), the Adminis-
trator shall notify the  applicant or registrant, in writing, by cer-
tified mail. The Administrator shall not thereafter make available
for inspection such data until thirty days after receipt of the notice
by the applicant or registrant. During this period, the  applicant or
registrant may institute an action in an appropriate district court
for a declaratory judgment as to whether such information is sub-
ject to protection under subsection (b).
    (d) LIMITATIONS.—
        (1) All information concerning the objectives, methodology,
    results, or significance of any test or experiment performed on
    or with  a  registered or previously registered pesticide or  its
    separate ingredients, impurities, or degradation products, and
    any information concerning the effects of such pesticide on any
    organism or the behavior of such pesticide in the environment,
    including, but not limited to, data on safety to fish and wildlife,
    humans  and  other mammals, plants, animals,  and soil, and
    studies  on persistence, translocation  and  fate in the environ-
    ment, and metabolism, shall be available  for disclosure to the
    public. The use of such data for any registration purpose shall
    be governed by section 3 of this Act.  This paragraph does not
    authorize the disclosure of any information that—
            (A) discloses  manufacturing  or quality control proc-
        esses,
            (B) discloses the details of any methods for testing, de-
        tecting,  or measuring the quantity  of any  deliberately
        added inert ingredient of a pesticide, or
            (C) discloses the identity or percentage quantity of any
        deliberately added inert ingredient of a pesticide,
    unless the Administrator has first determined  that disclosure
    is necessary to protect against  an  unreasonable risk  of injury
    to health or the environment.
        (2)  Information concerning production, distribution, sale,
    or inventories  of a pesticide that is otherwise entitled to con-
    fidential treatment under subsection (b) of this section may be
    publicly disclosed in connection with a public proceeding to de-
    termine whether a pesticide, or any ingredient of a pesticide,
    causes unreasonable adverse effects on health or the environ-
    ment, if the Administrator determines that such disclosure is
    necessary in the public interest.
        (3) If  the  Administrator proposes to  disclose  information
    described in clause (A), (B), or (C) of paragraph (1) or in para-
    graph (2) of this subsection, the Administrator shall notify by
    certified  mail the submitter of such information of the intent
    to release  such information. The Administrator may not re-
    lease such information, without the  submitter's consent, until
    thirty days after the submitter has been furnished such notice.
    Where the Administrator finds that disclosure of information
    described in clause (A), (B), or (C) of paragraph (1) of this sub-
    section is necessary to avoid or lessen  an imminent and sub-

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Sec. 10	FIFRA	70

    stantial risk of injury to the public health, the Administrator
    may set such shorter period of notice  (but not less than ten
    days) and such method of notice as the Administrator finds ap-
    propriate. During such period the data submitter may institute
    an action in an appropriate district court to enjoin or limit the
    proposed disclosure. The court may enjoin disclosure, or limit
    the disclosure or the parties to whom disclosure shall be made,
    to the extent that—
            (A) in the case of  information described in clause (A),
        (B), or (C) of paragraph (1) of this subsection, the proposed
        disclosure is not required to protect against an unreason-
        able risk of injury to health or the environment; or
            (B) in the case of  information described in paragraph
        (2) of this subsection,  the public interest  in availability of
        the information in the  public proceeding does not outweigh
        the interests in  preserving the confidentiality of the infor-
        mation.
    (e) DISCLOSURE TO CONTRACTORS.—Information otherwise pro-
tected from disclosure to the public under subsection (b) of this sec-
tion may be disclosed to contractors with  the United States and
employees of such contractors if,  in the opinion of the  Adminis-
trator, such disclosure is necessary for the satisfactory performance
by the contractor of a contract with the United States for the per-
formance of work in connection with this Act and under such condi-
tions as the Administrator may specify. The Administrator shall re-
quire as a condition to the disclosure of information under this sub-
section that the person receiving it take  such security precautions
respecting the information as the Administrator shall by regulation
prescribe.
    (f) PENALTY FOR DISCLOSURE BY FEDERAL  EMPLOYEES.—(1)
Any office or employee of the United States  or former officer or em-
ployee  of the United States who, by virtue  of such employment or
official position, has obtained possession of, or has access to, mate-
rial the disclosure of which is  prohibited by subsection (b) of this
section, and who, knowing that disclosure of such material is pro-
hibited  by such subsection, willfully discloses the material in any
manner to any person not entitled to receive it, shall be fined not
more than $10,000 or imprisoned  for  not more than  one year, or
both. Section 1905 of title 18 of the United States  Code shall not
apply with respect to the publishing, divulging, disclosure, or mak-
ing known of, or making available, information reported or other-
wise obtained under this Act.  Nothing in  this Act shall preempt
any civil remedy under State or Federal law for wrongful disclosure
of trade secrets.
    (2)  For the purposes of this section, any  contractor with the
United States who is furnished information as authorized by sub-
section (e) of this section, or any employee  of any such contractor,
shall be considered to be an employee of the United States.
    (g)  DISCLOSURE TO  FOREIGN  AND MULTINATIONAL  PESTICIDE
PRODUCERS.—(1) The Administrator shall  not knowingly disclose
information submitted by an applicant or registrant under this Act
to any employee or agent of any business or other  entity engaged
in the production, sale, or distribution of pesticides  in countries
other than the United States  or in addition to the United States

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71	FIFRA	Sec. 11

or to any other person who intends to deliver such data to such for-
eign or multinational business or entity unless the applicant or reg-
istrant has consented to such  disclosure. The Administrator shall
require an affirmation from any person who intends to inspect data
that such person does not seek access to the data for purposes of
delivering it  or offering it for  sale to  any such business or  entity
or its agents  or employees and will not purposefully deliver or neg-
ligently cause the data to be delivered to such business or  entity
or its agents  or employees. Notwithstanding any other provision of
this subsection, the Administrator may disclose  information to any
person in connection with a public proceeding under law or regula-
tion, subject  to restrictions on the availability of information con-
tained elsewhere in this Act, which information  is relevant to a  de-
termination by the Administrator with respect to whether a pes-
ticide, or any ingredient of a pesticide,  causes unreasonable adverse
effects on health or the environment.
    (2) The Administrator shall maintain records of the names of
persons to whom data are disclosed under this  subsection and the
persons or organizations they represent and shall inform the appli-
cant or registrant of the names and affiliations of such persons.
    (3) Section 1001 of title  18 of the United States Code  shall
apply to any affirmation  made under paragraph (1) of this sub-
section.
SEC. 11. [136i] USE OF RESTRICTED USE PESTICIDES; APPLICATORS.
    (a) CERTIFICATION PROCEDURE.—
        (1) FEDERAL CERTIFICATION.—In  any  State  for which a
    State plan for applicator certification has not been approved by
    the Administrator, the Administrator, in consultation with the
    Governor of such State, shall conduct a program for the certifi-
    cation of applicators of pesticides.  Such program  shall conform
    to the requirements imposed upon the States under the  provi-
    sions  of subsection (a)(2) of this section and shall not require
    private applicators to take any examination to establish com-
    petency in the use of pesticides. Prior to the implementation of
    the  program, the Administrator shall publish in the Federal
    Register  for review and comment  a  summary of the Federal
    plan for applicator certification and shall make generally avail-
    able  within the State copies of the  plan. The  Administrator
    shall hold public hearings  at one or more locations within the
    State if so  requested by the Governor of such State during the
    thirty days following publication of the Federal Register notice
    inviting comment on the Federal  plan. The hearings shall be
    held within thirty days following  receipt of the  request from
    the  Governor. In any  State  in  which the Administrator con-
    ducts a certification program, the  Administrator may require
    any person engaging in the commercial application, sale, offer-
    ing for sale, holding for sale, or distribution of  any pesticide
    one or more uses of which have been classified  for restricted
    use to maintain such records and submit such reports concern-
    ing  the commercial application, sale, or  distribution of such
    pesticide  as the  Administrator may be regulation prescribe.
    Subject  to paragraph  (2), the Administrator shall prescribe
    standards for the certification of applicators of pesticides. Such

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Sec. 11	FIFRA	72

    standards shall provide that to be certified, an individual must
    be determined to be competent  with  respect to the use and
    handling of pesticides, or to the  use and handling of the pes-
    ticide or class of pesticides covered by  such individual's certifi-
    cation. The certification standard for a private applicator shall,
    under a State plan submitted  for approval, be deemed fulfilled
    by the applicator completing a certification form. The Adminis-
    trator  shall further  assure that  such  form  contains adequate
    information and affirmations to carry out the intent of this Act,
    and may include  in  the  form an affirmation that the private
    applicator has completed a training program approved by the
    Administrator so long as the program does not require the pri-
    vate applicator to take, pursuant to a requirement  prescribed
    by the Administrator, any examination to establish competency
    in the use of the pesticide. The Administrator may require any
    pesticide dealer participating  in  a certification program to be
    licensed under a State licensing program approved by the Ad-
    ministrator.
        (2) STATE CERTIFICATION.—If any  State, at any time, de-
    sires to certify applicators of  pesticides, the Governor of such
    State shall submit a  State plan for such purpose. The Adminis-
    trator shall approve the plan submitted by any State, or any
    modification thereof, if such plan in the Administrator's judg-
    ment—
            (A) designates a State agency as the  agency respon-
        sible for administering the plan throughout the State;
            (B) contains satisfactory assurances that such agency
        has or will have the legal authority and qualified person-
        nel necessary to  carry out the plan;
            (C) gives satisfactory assurances that the  State will
        devote adequate funds to the administration of the plan;
            (D) provides that the  State agency will make such re-
        ports  to the  Administrator in such  form  and  containing
        such information as the Administrator may from time to
        time require; and
            (E) contains satisfactory assurances that State stand-
        ards for the certification  of  applicators  of pesticides con-
        form with those  standards prescribed by the Administrator
        under paragraph (1).
    Any State certification program under this section shall  be
    maintained in accordance with the State plan approved under
    this section.
    (b) STATE PLANS.—If the Administrator rejects a plan submit-
ted under subsection  (a)(2), the  Administrator shall  afford the
State submitting the  plan due notice and opportunity for hearing
before so doing. If the Administrator approves  a  plan submitted
under subsection (a)(2), then such State shall certify applicators of
pesticides with respect to such State. Whenever the Administrator
determines that a State  is not administering the certification pro-
gram in accordance with the plan approved under this section, the
Administrator shall so notify the  State and provide for a hearing
at the request of the State, and, if appropriate corrective action is
not taken within a reasonable time, not to exceed ninety days, the
Administrator shall withdraw approval of such plan.

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73	FIFRA	Sec. 12

    (c)  INSTRUCTION IN  INTEGRATED PEST MANAGEMENT  TECH-
NIQUES.—Standards prescribed by the Administrator for the certifi-
cation of applicators of pesticides under subsection  (a),  and the
State plans submitted to the Administrator under subsection (a),
shall include provisions for making instructional materials concern-
ing integrated pest management techniques available  to individ-
uals at their request in accordance with the provisions of section
23(c) of this Act, but such plans may not require that any individ-
ual receive instruction concerning such techniques or be shown to
be competent with respect to the use of such techniques.  The Ad-
ministrator and States implementing such plans shall provide that
all interested individuals  are notified of the availability of such in-
structional materials.
    (d)  IN GENERAL.—No regulations prescribed by the Adminis-
trator for carrying out the provisions of this Act shall require any
private  applicator to maintain any records or file  any reports  or
other documents.
    (e)  SEPARATE STANDARDS.—When  establishing or approving
standards for licensing or certification, the Administrator shall es-
tablish separate standards for commercial and private applicators.
SEC. 12. [136j] UNLAWFUL ACTS.
    (a) IN GENERAL.—
        (1) Except as provided by subsection (b), it shall be unlaw-
    ful for any person in any State to distribute or sell to any per-
    son—
            (A) any pesticide that is not registered under section
        3 or whose registration  has been canceled or suspended,
        except to the extent that distribution or sale otherwise has
        been authorized by the Administrator under this Act;
            (B) any registered pesticide if any claims made  for it
        as a  part of its  distribution or sale substantially  differ
        from any claims made for it as a part of the statement re-
        quired in  connection with its registration under section 3;
            (C) any registered pesticide the composition of which
        differs at  the time of its distribution or sale from its com-
        position as described in the statement required in connec-
        tion with its registration under section 3;
            (D) any pesticide which has not been colored or discol-
        ored pursuant to the provisions of section 25(c)(5);
            (E) any pesticide  which is adulterated or misbranded;
        or
            (F) any device which is misbranded.
        (2) It shall be unlawful for any person—
            (A) to detach, alter,  deface, or destroy, in whole or  in
        part, any labeling required under this Act;
            (B) to refuse to—
                (i) prepare, maintain,  or submit any records  re-
            quired by or under section 5, 7, 8, 11, or 19;
                (ii) submit any reports required by or  under sec-
            tion 5, 6, 7, 8, 11, or 19; or
                (iii)  allow  any  entry,   inspection,  copying   of
            records, or sampling authorized by this Act;

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Sec. 12	FIFRA	74

            (C) to give a guaranty or undertaking provided for in
        subsection (b) which is false in any particular, except that
        a person who receives and relies upon a guaranty author-
        ized under subsection (b) may give a guaranty to the same
        effect, which guaranty shall contain, in addition to the per-
        son's own name and address, the name and address of the
        person residing in the United States from whom the per-
        son received the guaranty or undertaking;
            (D) to use for the person's own advantage or to reveal,
        other than to the Administrator, or officials or employees
        of the  Environmental  Protection Agency or other  Federal
        executive agencies, or to the courts, or to physicians, phar-
        macists, and other qualified persons, needing such  infor-
        mation for the performance of their duties, in  accordance
        with such directions as the Administrator may prescribe,
        any information acquired  by authority of this Act which is
        confidential under this Act;
            (E) who is a registrant, wholesaler, dealer,  retailer, or
        other distributor to  advertise a product registered under
        this Act for restricted use without  giving the  classification
        of the product assigned to it under section 3;
            (F) to distribute or sell, or to make available  for use,
        or to use, any registered  pesticide classified for restricted
        use for some or all purposes other than in accordance with
        section 3(d)  and any regulations thereunder, except that it
        shall not be unlawful  to sell, under regulations issued by
        the Administrator,  a restricted use pesticide to a person
        who is not  a certified applicator for application by a  cer-
        tified applicator;
            (G) to use any registered pesticide in a manner incon-
        sistent with its labeling;
            (H) to  use any pesticide which is  under  an experi-
        mental use  permit contrary to the provisions of such per-
        mit;
            (I) to violate any order issued under section 13;
            (J) to violate any suspension order issued  under  sec-
        tion 3(c)(2)(B), 4, or 6;
            (K) to violate any cancellation order issued under this
        Act or to fail to submit a  notice in accordance with section
        6(g);
            (L) who is a producer to violate  any of the provisions
        of section 7;
            (M) to knowingly falsify all or part  of any  application
        for registration,  application for experimental use permit,
        any information submitted to the Administrator pursuant
        to section 7, any records required to be maintained pursu-
        ant to this Act, any report filed under this Act, or any in-
        formation marked as confidential and submitted to the Ad-
        ministrator  under any provision of this Act;
            (N) who is a registrant, wholesaler,  dealer,  retailer, or
        other distributor to fail to file reports required by this Act;
            (O) to add any substance to, or take any substance
        from, any pesticide in a manner that may defeat the pur-
        pose of this  Act;

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75	FIFRA	Sec. 13

            (P) to use any pesticide in tests on human beings un-
        less such human beings (i) are fully informed of the nature
        and purposes of the test and of any physical  and mental
        health  consequences  which  are  reasonably  foreseeable
        therefrom, and  (ii) freely volunteer to participate in the
        test;
            (Q) to falsify all or part of any information relating to
        the testing of any pesticide (or any ingredient, metabolite,
        or degradation  product  thereof),  including  the  nature  of
        any protocol, procedure, substance,  organism,  or equip-
        ment used,  observation  made, or conclusion  or  opinion
        formed, submitted to the Administrator, or that the person
        knows will be furnished  to the Administrator  or  will be-
        come  a part  of  any records required to be maintained by
        this Act;
            (R) to submit to the  Administrator data known to be
        false in support  of a registration; or
            (S) to violate any  regulation issued under  section 3(a)
        or 19.
    (b) EXEMPTIONS.—The penalties  provided for a violation  of
paragraph (1) of subsection (a)  shall not apply to—
        (1) any person who establishes a guaranty signed  by, and
    containing the name and  address of, the registrant or person
    residing in the United States from whom the person purchased
    or received in good  faith the pesticide in the same unbroken
    package, to the effect that  the pesticide was lawfully registered
    at the time of sale and delivery to the person, and that it com-
    plies with the other  requirements of this Act,  and in such case
    the guarantor shall be subject to the penalties which would
    otherwise attach  to the person holding the guaranty under the
    provisions of this Act;
        (2) any carrier while lawfully shipping, transporting, or de-
    livering for shipment any pesticide or device,  if such carrier
    upon request of any  officer or employee duly designated by the
    Administrator shall  permit such officer or employee to  copy all
    of its records concerning such pesticide or device;
        (3) any public official while engaged in the performance of
    the official duties of  the public official;
        (4) any person  using  or possessing any pesticide  as pro-
    vided by an experimental  use permit in effect with respect  to
    such pesticide and such use or possession; or
        (5) any person who ships  a substance or mixture of sub-
    stances being put through tests in which the purpose is  only
    to determine its value for pesticide purposes or to determine its
    toxicity or other properties and from which the user does not
    expect to receive any benefit in pest control from its use.
SEC. 13. [136k] STOP SALE, USE, REMOVAL, AND SEIZURE.
    (a) STOP SALE, ETC., ORDERS.—Whenever any pesticide or de-
vice is found by the Administrator in any State and there is reason
to believe on the basis of inspection or tests that such pesticide or
device is in violation of  any of the provisions of this Act,  or  that
such pesticide or device  has been or is intended to be distributed
or sold in violation of any such provisions, or when the registration

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Sec. 13	FIFRA	76

of the pesticide has been canceled by a final order or has been sus-
pended, the Administrator may issue a written or printed "stop
sale,  use, or removal" order to any person who owns, controls,  or
has custody of such pesticide  or device, and after receipt of such
order no person shall sell, use,  or remove the pesticide or device de-
scribed in the order except in accordance with the provisions of the
order.
    (b) SEIZURE.—Any pesticide or device that is being transported
or, having been transported, remains unsold or in original unbro-
ken packages, or that is  sold  or offered for sale in any State,  or
that is imported from a foreign country, shall be liable to be pro-
ceeded against in any district court in the district where it is found
and seized for confiscation by  a process in rem for condemnation
if—
        (1) in the case of a pesticide—
            (A) it is adulterated or misbranded;
            (B) it is not  registered pursuant to the provisions  of
        section 3;
            (C) its labeling fails to bear the information required
        by this Act;
            (D) it is  not colored or discolored and such coloring  or
        discoloring is required  under this Act; or
            (E) any of the claims made for it or any of the direc-
        tions  for its  use  differ in  substance from the representa-
        tions  made in connection with its registration;
        (2) in the case of a device, it is misbranded; or
        (3) in the case of a pesticide or device, when used in ac-
    cordance with the requirements imposed under this Act and  as
    directed by the  labeling, it nevertheless causes unreasonable
    adverse effects on the environment.
In the case of a plant regulator, defoliant,  or desiccant, used in ac-
cordance with the label claims and recommendations, physical  or
physiological effects on plants or parts thereof shall not be deemed
to be  injury, when such effects are the purpose for which the plant
regulator, defoliant, or desiccant was applied.
    (c) DISPOSITION AFTER CONDEMNATION.—If the pesticide or de-
vice is condemned it shall, after entry of the decree,  be disposed of
by destruction or sale as the court may direct and the proceeds, if
sold,  less the court  costs, shall be paid into the Treasury of the
United States, but the pesticide or device shall not be sold contrary
to the provisions of this Act or  the laws of the jurisdiction in which
it is sold. On payment of the costs of the condemnation proceedings
and the execution and delivery of a good and sufficient bond condi-
tioned that the pesticide  or device shall not be sold or otherwise
disposed of contrary to the provisions of the Act or the laws of any
jurisdiction in which  sold, the  court may direct that such pesticide
or device be delivered to the owner thereof. The proceedings of such
condemnation cases shall conform, as near as may  be to the pro-
ceedings in admiralty, except  that either  party  may demand trial
by jury of any issue of fact joined in any case, and all such proceed-
ings shall be  at the suit of and in the name of the United States.
    (d) COURT COSTS, ETC.—When a decree of condemnation is en-
tered against  the pesticide or device, court costs and fees, storage,

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77	FIFRA	Sec. 14

and other proper expenses shall be awarded against the person, if
any, intervening as claimant of the pesticide or device.
SEC. 14. [1361] PENALTIES.
    (a) CIVIL PENALTIES.—
    (1) IN GENERAL.—Any registrant, commercial applicator, whole-
    saler, dealer,  retailer, or other distributor who violates  any
    provision of this Act may be assessed a civil penalty by the Ad-
    ministrator of not more than $5,000 for each offense.
        (2) PRIVATE APPLICATOR.—Any private applicator or other
    person not included in paragraph (1) who violates any provi-
    sion of this Act subsequent to receiving a written warning from
    the Administrator or  following a  citation for a prior violation,
    may be assessed  a civil penalty  by the Administrator of not
    more than $1,000  for each offense, except that any applicator
    not included under paragraph (1) of this subsection who holds
    or applies registered pesticides, or uses dilutions of registered
    pesticides, only to provide a  service of controlling pests without
    delivering any unapplied pesticide to any person so served, and
    who violates any provision of this Act may be assessed a civil
    penalty by the Administrator of not  more  than $500 for the
    first offense nor more than $1,000 for each subsequent offense.
        (3) HEARING.—No civil penalty shall be assessed unless the
    person charged shall  have been given notice and opportunity
    for a hearing  on  such charge in  the  county, parish,  or incor-
    porated city of the residence of the person charged.
        BUDETERMINATION  OF  PENALTY.—In  determining  the
    amount of the penalty, the Administrator shall consider the ap-
    propriateness of such  penalty to the size of the business of the
    person charged, the effect on the person's ability to continue in
    business, and the  gravity of the  violation.  Whenever the Ad-
    ministrator finds  that the violation occurred despite the exer-
    cise of due care or did not cause  significant harm to health or
    the environment, the Administrator may issue a warning in
    lieu of assessing a penalty.
        (5) REFERENCES TO ATTORNEY GENERAL.—In case of inabil-
    ity to collect such civil penalty or failure of any person to pay
    all, or such portion of such  civil penalty as the Administrator
    may determine, the Administrator shall refer the matter to the
    Attorney General,  who shall recover such amount by  action in
    the appropriate United States district court.
    (b) CRIMINAL PENALTIES.—
       (1) IN GENERAL.—
            (A) Any registrant, applicant for a registration, or pro-
        ducer who knowingly violates any  provision of this Act
       shall be fined not more than $50,000 or imprisoned for not
       more than 1 year, or both.
            (B) Any commercial applicator of a restricted use pes-
       ticide, or any other person not described in subparagraph
       (A)  who  distributes or sells pesticides or devices,  who
       knowingly violates any provision of this Act shall be fined
       not more than $25,000 or imprisoned for not more than 1
       year, or both.

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Sec. 15	FIFRA	78

        (2) PRIVATE APPLICATOR.—Any private applicator or other
    person not included in paragraph (1) who knowingly violates
    any provision of this Act shall be  guilty of a  misdemeanor and
    shall on conviction be fined not more than $1,000, or impris-
    oned for not more than 30 days, or both.
        (3) DISCLOSURE OF INFORMATION.—Any person, who, with
    intent to defraud, uses or reveals information relative to for-
    mulas of products acquired under the authority of section 3,
    shall be fined not more than $10,000, or imprisoned for not
    more than three years, or both.
        (4) ACTS OF OFFICERS, AGENTS, ETC.—When construing and
    enforcing the provisions of this Act, the act, omission, or failure
    of any officer, agent, or other person acting for or employed by
    any person shall  in every case be also deemed to be the act,
    omission, or failure of such person as well as  that of the person
    employed.
SEC. 15. [136m] INDEMNITIES.
    (a) GENERAL INDEMNIFICATION.—
        (1) IN GENERAL.—Except as otherwise provided in this sec-
    tion, if—
            (A) the Administrator notifies a registrant under sec-
        tion 6(c)(l) that the Administrator intends  to suspend a
        registration or that an  emergency order  of suspension of a
        registration under section 6(c)(3) has been issued;
            (B) the  registration in question is  suspended  under
        section 6(c), and thereafter is canceled under section 6(b),
        6(d), or 6(f); and
            (C) any person who owned any quantity of the pes-
        ticide immediately  before  the  notice   to the registrant
        under subparagraph (A) suffered losses  by reason of sus-
        pension or cancellation of the  registration;
    the Administrator shall make  an indemnity payment to the
    person.
        (2) EXCEPTION.—Paragraph (1) shall not apply if the Ad-
    ministrator finds that the person—
            (A) had knowledge of facts that, in themselves, would
        have shown that the pesticide did not  meet the require-
        ments of section 3(c)(5) for registration; and
            (B) continued thereafter to produce the pesticide with-
        out giving timely  notice of such facts to the Administrator.
        (3) REPORT.—If the Administrator takes an action under
    paragraph  (1) that requires the  payment of indemnification,
    the Administrator shall report to the Committee on Agriculture
    of the House of Representatives, the Committee on Agriculture,
    Nutrition, and Forestry of the Senate, and the Committees on
    Appropriations of the  House of Representatives and the Senate
    on—
            (A) the action  taken that requires the  payment  of
        indemnification;
            (B) the reasons for taking the action;
            (C) the estimated cost of the payment; and
            (D) a request for  the  appropriation of funds for the
        payment.

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79	FIFRA	Sec. 15

        (4) APPROPRIATION.—The Administrator may not make a
    payment of indemnification under paragraph (1) unless a spe-
    cific line item appropriation of funds has been made in advance
    for the payment.
    (b) INDEMNIFICATION OF END USERS, DEALERS, AND DISTRIBU-
TORS.—
        (1) END USERS.—If—
            (A) the Administrator notifies a registrant under sec-
        tion 6(c)(l) that the Administrator intends  to suspend a
        registration or that an emergency order of suspension of a
        registration under section 6(c)(3) has been issued;
            (B) the registration in question is suspended under
        section 6(c), and thereafter is canceled under section 6(b),
        6(d), or 6(f); and
            (C) any person who, immediately  before the notice to
        the registrant under subparagraph (A), owned any quan-
        tity of the  pesticide for purposes of applying or using the
        pesticide as an end user, rather than  for purposes of dis-
        tributing or selling it or further processing it for distribu-
        tion or sale, suffered a loss by reason of the  suspension or
        cancellation of the pesticide;
    the person shall  be entitled to an indemnity  payment under
    this subsection  for such quantity of the pesticide.
        (2) DEALERS AND DISTRIBUTORS.—
            (A) Any  registrant, wholesaler, dealer,  or  other dis-
        tributor (hereinafter in this paragraph referred  to as a
        "seller") of a registered pesticide who  distributes  or sells
        the pesticide directly to any person not described as an
        end user in  paragraph  (1)(C) shall, with respect to any
        quantity of the pesticide that such person cannot use or re-
        sell as a result of the suspension or cancellation of the pes-
        ticide, reimburse such person for the cost of first acquiring
        the pesticide from the  seller  (other than the cost of trans-
        portation, if any),  unless the seller provided to the person
        at the time of distribution or sale a notice, in writing, that
        the pesticide  is not subject to reimbursement by the seller.
            (B) If—
                (i)  the Administrator notifies  a registrant under
            section 6(c)(l) that the Administrator intends to sus-
           pend a registration or that an emergency order of sus-
           pension of a registration  under section 6(c)(3) has been
           issued;
                (ii) the  registration in  question  is suspended
           under  section 6(c), and  thereafter is  canceled under
           section 6(b), 6(d), or 6(f);
                (iii) any person who,  immediately before the notice
           to the registrant under clause (i)—
                    (I) had not been notified in  writing by the
                seller, as  provided under subparagraph (A), that
                any quantity of the  pesticide owned by such per-
                son is not subject to reimbursement by the seller
                in  the event of suspension or  cancellation of the
                pesticide; and

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Sec. 15	FIFRA	80

                   (II) owned any quantity of the  pesticide  for
                purposes of—
                       (aa) distributing or selling it; or
                       (bb) further processing it for distribution
                   or sale directly to an end user;
            suffered a loss by reason of the suspension or cancella-
            tion of the pesticide; and
                (iv) the Administrator determines on the basis of
            a claim of loss submitted to the Administrator by the
            person, that the seller—
                   (I) did not provide the notice specified in sub-
                paragraph (A) to such person; and
                   (II) is and will continue to be unable to pro-
                vide  reimbursement to such  person, as provided
                under subparagraph (A), for the loss referred to in
                clause (iii),  as  a  result of the insolvency or bank-
                ruptcy of the seller and the seller's  resulting  in-
                ability to provide such reimbursement;
        the person shall  be entitled  to an  indemnity payment
        under this subsection for such quantity of the  pesticide.
            (C)  If an indemnity  payment is  made by the United
        States under  this paragraph,  the United  States shall be
        subrogated to any  right that would  otherwise be held
        under this paragraph by  a seller who is unable to make a
        reimbursement in accordance with this paragraph with re-
        gard to  reimbursements  that otherwise would  have been
        made by the seller.
        (3)  SOURCE.—Any payment required  to be  made  under
    paragraph (1) or (2) shall be made from the appropriation pro-
    vided under  section 1304 of title 31, United States Code.
        (4) ADMINISTRATIVE SETTLEMENT.—An administrative set-
    tlement of a claim for such indemnity may be made in accord-
    ance with the third paragraph of section 2414 of title 28, Unit-
    ed States Code, and shall be regarded as if it were made under
    that section for purposes of section 1304 of title  31, United
    States Code.
    (c) AMOUNT OF PAYMENT.—
        (1)  IN GENERAL.—The  amount of an indemnity payment
    under subsection  (a) or  (b) to any person shall be determined
    on the basis of the cost of the pesticide  owned by  the person
    (other than the cost of transportation, if any) immediately  be-
    fore the issuance  of the notice to the registrant referred to in
    subsection (a)(l)(A), (bXD(A),  or (b)(2)(B)(i), except  that in no
    event shall  an indemnity payment to  any person  exceed the
    fair market  value of the pesticide owned by the person imme-
    diately before the  issuance of the notice.
        (2) SPECIAL RULE.—Notwithstanding any other provision of
    this Act, the Administrator may provide a reasonable time for
    use or other disposal of the pesticide. In determining the quan-
    tity of any pesticide for which indemnity shall be paid under
    this section,  proper adjustment shall be made for  any pesticide
    used or otherwise disposed of by the owner.

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81	FIFRA	Sec. 17

SEC. 16. [136n] ADMINISTRATIVE PROCEDURE; JUDICIAL REVIEW.
    (a) DISTRICT COURT REVIEW.—Except as otherwise provided in
this Act, the  refusal of the Administrator  to cancel or suspend a
registration or to change a classification not following a hearing
and other final actions of the Administrator not committed to the
discretion of the Administrator by law are judicially reviewable by
the district courts of the United States.
    (b) REVIEW BY COURT OF APPEALS.—In the  case of actual con-
troversy as to the validity of any order issued by the Administrator
following a  public hearing, any  person  who will  be adversely  af-
fected by such order and who had been  a party to the proceedings
may obtain judicial review by  filing in the United  States court of
appeals for  the circuit wherein such person resides or has a place
of business, within 60 days after the entry of such order, a petition
praying that the order  be set aside in whole or in part. A copy of
the petition shall be forthwith transmitted by the clerk of the court
to the Administrator or any officer designated by the Administrator
for that purpose, and thereupon the Administrator shall file in the
court  the record  of the proceedings  on which  the Administrator
based the Administrator's order, as provided in section 2112 of title
28, United States Code. Upon the filing of such petition the court
shall have exclusive jurisdiction to affirm  or set  aside the  order
complained  of in whole or in part. The court shall consider all evi-
dence of record. The order of the Administrator shall be sustained
if it is supported by substantial evidence when considered on the
record as a whole. The judgment of the court affirming or setting
aside, in whole or in part, any order under this section shall be
final, subject to review  by the Supreme Court of the United States
upon certiorari or certification as provided  in section  1254 of title
28 of the United States Code. The commencement of proceedings
under this section shall not, unless specifically ordered by the court
to the contrary, operate as a stay of an order.
    (c) JURISDICTION OF DISTRICT COURTS.—The district courts of
the United  States are  vested with jurisdiction specifically  to en-
force, and to prevent and restrain violations of, this Act.
    (d) NOTICE OF JUDGMENTS.—The Administrator shall, by publi-
cation in such manner as the Administrator may prescribe, give no-
tice of all judgments entered in actions instituted under the author-
ity of this Act.
SEC. 17. [136o] IMPORTS AND EXPORTS.
    (a) PESTICIDES AND DEVICES INTENDED FOR EXPORT.—Notwith-
standing any other provision this Act, no pesticide or device or  ac-
tive ingredient used in producing a pesticide intended solely for  ex-
port to any foreign country  shall be deemed in  violation of this
Act—
        (1) when prepared or packed according to the specifications
    or directions of the  foreign purchaser, except that producers of
    such pesticides and devices and active ingredients used in pro-
    ducing pesticides shall be subject to sections 2(p), 2(q) (1) (A),
    (C), (D), (E), (G), and (H), 2(q) (2) (A), (B), (C) (i) and (iii), and
    (D), 7, and 8 of this Act; and
        (2) in the case  of any pesticide other than a pesticide reg-
    istered under section 3 or sold under  section 6(a)  (1) of this
    Act, if,  prior to export,  the foreign purchaser has signed a

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Sec. 18	FIFRA	82

    statement acknowledging that the purchaser understands that
    such pesticide is not registered for use  in  the United States
    and cannot be sold in the United States under this Act.
A copy of that statement shall be transmitted to an appropriate of-
ficial of the government of the importing country.
    (b) CANCELLATION NOTICES FURNISHED TO  FOREIGN  GOVERN-
MENTS.—Whenever  a registration, or a cancellation or suspension
of the registration of a pesticide becomes  effective,  or ceases to be
effective, the Administrator shall transmit through the State De-
partment notification thereof to the governments of other countries
and to appropriate  international agencies. Such notification shall,
upon request, include all information related to  the cancellation or
suspension of the registration of the pesticide and information con-
cerning other pesticides that are registered under section 3 of this
Act and that could be used in lieu of such pesticide.
    (c) IMPORTATION OF  PESTICIDES AND DEVICES.—The Secretary
of the Treasury shall notify the Administrator of the arrival of pes-
ticides and devices and shall deliver to the Administrator,  upon the
Administrator's request,  samples of pesticides or devices which are
being imported into the  United States, giving notice  to the owner
or consignee, who may appear before the Administrator and have
the right to introduce testimony. If it appears from the examination
of a sample that it  is adulterated, or misbranded or otherwise vio-
lates the provisions set forth in this Act,  or  is  otherwise  injurious
to health or the  environment,  the  pesticide  or  device may be re-
fused admission, and the Secretary  of the  Treasury  shall refuse de-
livery to  the consignee and shall cause the destruction of any pes-
ticide or  device refused delivery which shall not be exported by the
consignee within 90 days from the date  of notice  of such refusal
under such  regulations as the Secretary of the  Treasury may pre-
scribe. The Secretary of the Treasury may deliver to  the consignee
such pesticide or device  pending examination and  decision in the
matter on execution of bond for the  amount of the full invoice value
of such pesticide or device, together with the duty thereon, and on
refusal to return such pesticide or device  for any cause to the cus-
tody of the Secretary of the Treasury, when demanded, for the pur-
pose of excluding them from the country,  or for  any other purpose,
said consignee shall  forfeit the full amount  of  said bond.  All
charges  for  storage,  cartage, and  labor  on  pesticides or  devices
which are refused admission or delivery shall be paid by the owner
or consignee, and in default of such payment shall constitute a lien
against any future  importation made by such owner  or consignee.
    (d) COOPERATION  IN INTERNATIONAL  EFFORTS.—The  Adminis-
trator shall,  in cooperation with the Department of State  and any
other appropriate Federal agency, participate and cooperate in any
international efforts  to  develop improved pesticide  research and
regulations.
    (e) REGULATIONS.—The Secretary of the  Treasury, in  consulta-
tion with the Administrator, shall prescribe regulations for the en-
forcement of subsection (c) of this section.
SEC. 18. [136p] EXEMPTION OF FEDERAL AND STATE AGENCD3S.
    The  Administrator may, at the Administrator's discretion, ex-
empt any Federal or State agency from any provision of this Act

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83	FIFRA	Sec. 19

if the Administrator  determines that emergency conditions exist
which require such exemption. The Administrator, in determining
whether or not such emergency conditions exist, shall consult with
the Secretary of Agriculture and the Governor of any State con-
cerned if they request such determination.
SEC. 19.  [136q] STORAGE, DISPOSAL, TRANSPORTATION, AND RECALL.
    (a) STORAGE, DISPOSAL, AND TRANSPORTATION.—
        (1)  DATA  REQUIREMENTS  AND  REGISTRATION OF  PES-
    TICIDES.—The  Administrator may require under section 3 or 6
    that—
            (A) the registrant or applicant for registration of a pes-
        ticide submit or cite data or information regarding meth-
        ods for the safe storage and disposal of excess quantities
        of the  pesticide to  support  the registration or continued
        registration of a pesticide;
            (B) the labeling of a pesticide  contain requirements
        and procedures for the transportation,  storage, and dis-
        posal of the pesticide, any container of the pesticide, any
        rinsate containing  the  pesticide,  or any other material
        used to contain or collect excess or spilled quantities of the
        pesticide; and
            (C) the registrant of a  pesticide provide  evidence  of
        sufficient financial and other resources to carry out a re-
        call plan under subsection (b), and provide for the  disposi-
        tion of the pesticide, in the  event of suspension and can-
        cellation of the pesticide.
        (2) PESTICIDES.—The Administrator may by regulation,  or
    as part of  an  order issued under section 6 or an  amendment
    to such an order—
            (A) issue requirements and procedures to be followed
        by any person who stores or transports a pesticide the reg-
        istration of which has been suspended or canceled;
            (B) issue requirements and procedures to be followed
        by any person who disposes of stocks of a pesticide the reg-
        istration of which has been suspended; and
            (C) issue requirements and procedures for the disposal
        of any pesticide the registration of which has been can-
        celed.
        (3) CONTAINERS, RINSATES, AND OTHER MATERIALS.—The
    Administrator  may by regulation, or as part of an order issued
    under section 6 or an amendment to such an order—
            (A) issue requirements and procedures to be followed
        by any person who stores or transports any container of a
        pesticide the registration of which has been suspended  or
        canceled, any rinsate containing the pesticide, or any other
        material used to contain or collect excess or spilled quan-
        tities of the pesticide;
            (B) issue  requirements and  procedures to be followed
        by any person who disposes of stocks of any container  of
        a  pesticide the registration of which has been suspended,
        any rinsate containing the pesticide, or any other material
        used to contain or collect excess or spilled quantities of the
        pesticide; and

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Sec. 19	FIFRA	84

            (C) issue requirements and procedures for the disposal
        of any container of a pesticide the registration of which
        has been canceled, any rinsate containing the pesticide, or
        any  other  material  used to contain or collect excess or
        spilled quantities of the pesticide.
    (b) RECALLS.—
        (1) IN GENERAL.—If the registration of a pesticide has been
    suspended and canceled under section 6, and  if the Adminis-
    trator finds that recall of the pesticide is necessary to protect
    health or the environment, the Administrator shall order a re-
    call of the pesticide in accordance with this subsection.
        (2) VOLUNTARY RECALL.—If, after determining under para-
    graph (1) that  a recall is necessary,  the Administrator finds
    that voluntary recall by the registrant and others in the chain
    of distribution may be as safe and effective as a mandatory re-
    call, the Administrator shall  request the registrant of the pes-
    ticide to  submit, within 60 days of the request, a plan for the
    voluntary recall of the  pesticide. If such a plan is requested
    and submitted, the Administrator shall approve the plan and
    order the registrant  to  conduct the recall in accordance with
    the plan unless the Administrator determines, after an infor-
    mal hearing,  that the plan is inadequate to protect health or
    the environment.
        (3) MANDATORY RECALL.—If, after determining under para-
    graph (1) that a recall is necessary, the Administrator does not
    request the submission of a plan under paragraph (2) or finds
    such a plan to  be  inadequate, the Administrator shall issue a
    regulation that prescribes a plan for the recall  of the pesticide.
    A regulation  issued  under this paragraph may apply to any
    person who is or was a registrant, distributor, or seller of the
    pesticide, or any successor in  interest to such a person.
        (4) RECALL PROCEDURE.—A regulation issued under this
    subsection may require any person that is subject to the regu-
    lation to—
            (A) arrange to make available one or more storage fa-
        cilities to receive and store the pesticide to which the re-
        call program applies, and inform the  Administrator of the
        location of each such facility;
            (B) accept and  store at such  a facility those existing
        stocks  of such pesticide  that are tendered by  any other
        person who obtained the  pesticide directly or indirectly
        from the person that is subject to such regulation;
            (C) on  the request of a person making such a tender,
        provide for proper transportation of the pesticide to a stor-
        age facility; and
            (D) take such reasonable steps as the regulation  may
        prescribe to inform persons who may be holders  of the pes-
        ticide of the terms of the recall regulation and  how those
        persons may tender the pesticide and arrange for transpor-
        tation of the pesticide to a storage  facility.
        (5) CONTENTS  OF RECALL PLAN.—A recall plan established
    under this subsection shall include—
            (A) the level in the distribution chain to which the re-
        call is to extend,  and a schedule for recall; and

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85	FIFRA	Sec. 19

            (B) the means to be used to verify the effectiveness of
        the recall.
        (6)  REQUIREMENTS OR PROCEDURES.—No requirement or
    procedure imposed in accordance  with paragraph  (2) of sub-
    section (a) may require the recall of existing stocks of the pes-
    ticide except as provided by this subsection.
    (c) STORAGE COSTS.—
        (1) SUBMISSION OF PLAN.—A registrant who wishes to be-
    come eligible for reimbursement of storage costs incurred as a
    result of a recall prescribed under subsection (b) for a pesticide
    whose registration has been suspended and canceled shall, as
    soon as practicable after the suspension of the registration of
    the pesticide, submit to the Administrator a plan for the  stor-
    age and disposal of the pesticide that meets criteria established
    by the Administrator by regulation.
        (2) REIMBURSEMENT.—Within  a reasonable period of time
    after such storage costs are  incurred and  paid  by the reg-
    istrant, the Administrator shall reimburse the registrant, on
    request, for—
            (A) none of the costs incurred by the registrant before
        the date of submission of the plan referred to in paragraph
        (1) to the Administrator;
            (B) 100 percent of the costs incurred by the registrant
        after the date of submission of the plan to the  Adminis-
        trator or the date of cancellation of the registration of the
        pesticide, whichever is later, but before the approval of the
        plan by the Administrator;
            (C) 50  percent of the costs incurred by the registrant
        during the  1-year period beginning on the date of the ap-
        proval of the plan by the Administrator or the date of can-
        cellation  of the registration of the pesticide, whichever is
        later;
            (D) none of the costs incurred by the registrant during
        the 3-year period beginning on the 366th day following ap-
        proval of the plan by the Administrator or the date of can-
        cellation  of the registration of the pesticide, whichever is
        later; and
            (E) 25  percent of the costs incurred by the registrant
        during the period beginning on the  first day of the 5th
        year following the date of the approval of the plan by the
        Administrator or the date of  cancellation of the registra-
        tion of the pesticide, whichever is later, and ending on the
        date that a disposal permit for the pesticide is issued by
        a State or an alternative plan for disposal of the pesticide
        in accordance with applicable law has been developed.
    (d) ADMINISTRATION OF STORAGE,  DISPOSAL, TRANSPORTATION,
AND RECALL PROGRAMS.—
        (1)  VOLUNTARY  AGREEMENTS.—Nothing  in this section
    shall be construed  as preventing  or  making unlawful  any
    agreement between  a seller  and a  buyer of any  pesticide or
    other substance regarding the ultimate allocation of the  costs
    of storage, transportation, or disposal of a pesticide.

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Sec. 19	FIFRA	86

        (2) RULE AND REGULATION REVIEW.—Section 25(a)(4) shall
    not apply to any regulation issued under subsection (a)(2) or
    (b).
        (3) LIMITATIONS.—No registrant shall be responsible under
    this section for a pesticide the registration of which is held by
    another person. No distributor or seller shall be responsible
    under this section for a pesticide that the distributor or seller
    did not hold or sell.
        (4) SEIZURE AND PENALTIES.—If the Administrator  finds
    that a person who is  subject  to a regulation or order under
    subsection (a)(2) or (b) has failed substantially to comply with
    that regulation or order, the  Administrator may take action
    under section 13 or 14 or obtain injunctive relief under section
    16(c) against such person or any successor  in interest of any
    such person.
    (e) CONTAINER DESIGN.—
        (1) PROCEDURES.—
            (A) Not later than 3 years after the  effective date of
        this  subsection, the Administrator  shall, in consultation
        with the heads of other interested Federal agencies, pro-
        mulgate regulations for  the design of pesticide containers
        that  will promote the safe storage and  disposal of pes-
        ticides.
            (B) The regulations  shall ensure, to the fullest extent
        practicable, that the containers—
                (i) accommodate procedures used for the removal
            of pesticides from the containers and the rinsing of the
            containers;
                (ii) facilitate the safe use of the containers, includ-
            ing elimination of splash  and  leakage  of  pesticides
            from the containers;
                (iii) facilitate  the  safe disposal  of the containers;
            and
                (iv) facilitate the  safe refill  and  reuse of  the
            containers.
        (2) COMPLIANCE.—The Administrator shall require compli-
    ance with the regulations referred to in paragraph (1) not later
    than 5 years after the effective date of this subsection.
    (f) PESTICIDE RESIDUE REMOVAL.—
        (1) PROCEDURES.—
            (A) Not later than 3 years after the  effective date of
        this  subsection, the Administrator  shall, in consultation
        with the heads of other interested Federal agencies, pro-
        mulgate regulations prescribing procedures and  standards
        for the removal of pesticides from containers prior to  dis-
        posal.
            (B) The regulations may—
                (i) specify, for each major type of pesticide con-
            tainer, procedures and standards providing for,  at  a
            minimum, triple rinsing  or the  equivalent  degree of
            pesticide removal;
                (ii)  specify procedures that  can  be  implemented
            promptly and easily in various circumstances and con-
            ditions;

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87	FIFRA	Sec. 19

                (iii) provide for reuse, whenever practicable, or
            disposal of rinse water and residue; and
                (iv) be coordinated with requirements for the rins-
            ing of containers imposed under the Solid Waste Dis-
            posal Act (42 U.S.C. 6901 et seq.).
            (C) The Administrator may, at the discretion  of the
        Administrator, exempt products intended solely for house-
        hold use from the requirements of this  subsection.
        (2) COMPLIANCE.—Effective beginning 5 years after the ef-
    fective date of this subsection, a State  may not exercise pri-
    mary enforcement responsibility under section 26, or certify an
    applicator  under  section 11, unless the Administrator  deter-
    mines that the State is carrying out an adequate  program to
    ensure compliance with this subsection.
        (3) SOLID WASTE DISPOSAL ACT.—Nothing in this subsection
    shall  affect the authorities or requirements concerning pes-
    ticide containers under the Solid Waste Disposal Act (42 U.S.C.
    6901).
    (g) PESTICIDE CONTAINER STUDY.—
        (1) STUDY.—
            (A) The Administrator shall conduct a study of options
        to encourage or require—
                (i) the return,  refill, and reuse of pesticide con-
            tainers;
                (ii) the development and use of pesticide formula-
            tions that facilitate the removal of pesticide residues
            from containers; and
                (iii) the  use of bulk storage facilities to reduce the
            number of pesticide containers requiring disposal.
            (B) In conducting the  study, the Administrator shall—
                (i) consult with the heads of other interested Fed-
            eral  agencies, State agencies, industry groups, and  en-
            vironmental organizations;  and
                (ii) assess the feasibility, costs, and environmental
            benefits of encouraging or requiring various measures
            or actions.
        (2) REPORT.—Not later than 2 years after the effective date
    of this subsection, the Administrator shall submit to Congress
    a report describing  the  results of the study  required  under
    paragraph  (1).
    (h) RELATIONSHIP TO SOLID WASTE DISPOSAL ACT.—
        (1) IN  GENERAL.—Nothing in  this section shall diminish
    the authorities or requirements of the Solid Waste Disposal Act
    (42 U.S.C. 6901 et seq.).
        (2) ANTIMICROBIAL PRODUCTS.—A household, industrial, or
    institutional  antimicrobial product that is  not subject to regu-
    lation under  the Solid Waste  Disposal Act  (42 U.S.C. 6901 et
    seq.) shall  not be  subject to the provisions of subsections (a),
    (e), and  (f),  unless  the  Administrator determines that such
    product must be subject to  such provisions to prevent an un-
    reasonable adverse effect on the environment.

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Sec. 20	FIFRA	88

SEC. 20. [136r] RESEARCH AND MONITORING.
    (a) RESEARCH.—The Administrator shall undertake  research,
including research by grant  or contract with other Federal agen-
cies, universities, or others as may  be necessary to carry out the
purposes of this Act, and the Administrator shall conduct research
into integrated  pest management in coordination with  the Sec-
retary of Agriculture. The Administrator shall also take care to en-
sure that such research does not duplicate research being under-
taken by any other Federal agency.
    (b) NATIONAL MONITORING PLAN.—The Administrator shall for-
mulate and periodically revise, in cooperation with other Federal,
State, or local agencies, a national plan for monitoring pesticides.
    (c) MONITORING.—The Administrator shall  undertake  such
monitoring activities,  including, but not  limited to monitoring in
air, soil, water, man, plants,  and animals, as may be necessary for
the implementation of this Act and  of the national pesticide mon-
itoring plan.  The Administrator shall establish  procedures  for the
monitoring of man and animals and  their environment for inciden-
tal pesticide exposure, including, but not limited to, the quantifica-
tion of incidental human and environmental pesticide pollution and
the secular trends thereof, and identification of  the sources of con-
tamination and their relationship  to human and environmental ef-
fects. Such activities shall be carried out in cooperation with other
Federal, State, and local agencies.
SEC. 21.  [136s]  SOLICITATION OF  COMMENTS; NOTICE OF PUBLIC
           HEARINGS.
    (a) SECRETARY OF AGRICULTURE.—The Administrator,  before
publishing regulations under this Act, shall solicit the views of the
Secretary of Agriculture in accordance with the procedure  described
in section 25(a).
    (b) SECRETARY OF HEALTH AND HUMAN SERVICES.—The Admin-
istrator, before publishing regulations under this Act for any public
health pesticide, shall  solicit the views of the Secretary of Health
and Human Services in the same  manner as the views of the Sec-
retary of Agriculture are solicited under section 25(a)(2).
    (c) VIEWS.—In addition to any other authority relating  to pub-
lic hearings and solicitation  of views, in  connection with the  sus-
pension or cancellation of a pesticide registration or any  other ac-
tions authorized under this Act, the  Administrator may, at the Ad-
ministrator's discretion, solicit the views  of all  interested persons,
either orally or in writing, and seek such advice from  scientists,
farmers, farm organizations, and other qualified  persons as the Ad-
ministrator deems proper.
    (d) NOTICE.—In connection with all public hearings under this
Act the Administrator shall publish  timely notice of such hearings
in the Federal Register.
SEC. 22. [136t] DELEGATION AND COOPERATION.
    (a) DELEGATION.—All  authority vested in the Administrator by
virtue of the provisions of this Act may with like force and effect
be executed by  such  employees  of  the Environmental Protection
Agency as the Administrator may designate for the purpose.
    (b) COOPERATION.—The Administrator shall  cooperate with the
Department of Agriculture, any other Federal agency, and any ap-

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89	FIFRA	Sec. 24

propriate agency of any State  or any political subdivision thereof,
in carrying out the provisions of this Act, and in securing uniform-
ity of regulations.
SEC. 23. [136u] STATE COOPERATION, AID, AND TRAINING.
    (a) COOPERATIVE AGREEMENTS.—The Administrator may enter
into cooperative agreements with States and Indian tribes—
        (1) to delegate to any  State or Indian tribe the authority
    to cooperate in the enforcement of this Act through the use of
    its personnel or facilities, to train personnel of the State or In-
    dian tribe to cooperate  in  the enforcement of this Act, and to
    assist States and Indian tribes in implementing cooperative en-
    forcement programs through grants-in-aid; and
        (2) to assist States  in  developing and administering State
    programs, and Indian tribes that enter into cooperative agree-
    ments, to  train and certify applicators  consistent with  the
    standards the Administrator prescribes.
Effective with the fiscal year beginning October 1, 1978, there are
authorized to be appropriated annually such funds as  may be nec-
essary for the Administrator to provide through cooperative agree-
ments an amount  equal to 50 percent  of the anticipated cost to
each  State or Indian  tribe, as agreed  to  under such cooperative
agreements, of conducting training  and certification programs dur-
ing such fiscal year. If funds  sufficient to pay 50 percent of the
costs for any  year are not appropriated, the share of each State and
Indian  tribe  shall  be  reduced in a like proportion  in  allocating
available funds.
    (b) CONTRACTS FOR TRAINING.—In addition, the Administrator
may enter into contracts with Federal, State, or Indian tribal agen-
cies for the purpose of  encouraging the training of certified applica-
tors.
    (c) INFORMATION AND EDUCATION.—The Administrator  shall, in
cooperation with the Secretary of Agriculture, use the services of
the cooperative State extension services to inform and educate pes-
ticide users about  accepted uses and other regulations made under
this Act.
SEC. 24. [136v] AUTHORITY OF STATES.
    (a) IN GENERAL.—A State may  regulate the sale or use of any
federally registered pesticide or device in the State, but only if and
to the extent  the regulation does not permit any sale or use prohib-
ited by this Act.
    (b)  UNIFORMITY.—Such  State shall not impose or continue in
effect any requirements for labeling or packaging in addition to or
different from those required under  this Act.
    (c) ADDITIONAL USES.—
        (1) A State may provide registration for additional uses of
    federally  registered pesticides formulated for  distribution and
    use within that State to meet special local needs in accord with
    the purposes of this Act  and if registration for such use has not
    previously been denied, disapproved, or canceled by the Admin-
    istrator. Such  registration  shall be  deemed registration under
    section 3 for all purposes of this Act, but shall authorize dis-
    tribution  and use only within such State.

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Sec. 25	FIFRA	90

        (2) A registration issued by a State under this subsection
    shall not be effective for more than ninety days if disapproved
    by the Administrator within that period. Prior to disapproval,
    the Administrator shall, except as provided in paragraph (3) of
    this subsection,  advise the State of the Administrator's inten-
    tion to disapprove and the reasons therefor, and provide the
    State time to respond. The Administrator shall not prohibit or
    disapprove a registration issued  by  a State under this sub-
    section (A) on the basis of lack of essentiality of a pesticide or
    (B) except as provided in paragraph (3) of this subsection, if its
    composition and use patterns are similar to those of a federally
    registered pesticide.
        (3) In  no instance may a State issue a registration for a
    food or feed use unless there exists a tolerance or exemption
    under the Federal Food, Drug, and Cosmetic Act that permits
    the residues of the pesticide on the food or feed.  If the Admin-
    istrator determines that a registration issued by a State is in-
    consistent with  the Federal Food, Drug, and Cosmetic Act, or
    the use of, a pesticide under a registration  issued by a State
    constitutes an imminent hazard, the Administrator may imme-
    diately disapprove the registration.
        (4) If the Administrator finds, in accordance with  stand-
    ards set forth in regulations issued  under  section 25 of this
    Act, that a State is not capable of exercising adequate controls
    to  assure that State registration under this section will be in
    accord with the purposes of this Act or has failed to exercise
    adequate controls, the Administrator may  suspend the author-
    ity of the State to register pesticides until such time as the Ad-
    ministrator is satisfied that the  State can and  will exercise
    adequate controls. Prior to any such suspension,  the Adminis-
    trator shall advise the State of the Administrator's intention to
    suspend and the reasons therefor and provide the State time
    to  respond.
SEC. 25. [136w] AUTHORITY OF ADMINISTRATOR.
    (a) IN GENERAL.—
        (1) REGULATIONS.—The Administrator is authorized in ac-
    cordance with the procedure described in paragraph (2), to pre-
    scribe regulations to carry out the provisions of this Act. Such
    regulations shall take  into account the difference in concept
    and usage between various classes of pesticides, including pub-
    lic health pesticides, and differences in environmental risk and
    the appropriate  data for evaluating such risk between agricul-
    tural, nonagricultural, and public health pesticides.
        (2) PROCEDURE.—
            (A) PROPOSED REGULATIONS.—At least 60 days prior to
        signing any proposed regulation for publication in the Fed-
        eral  Register, the  Administrator shall provide the  Sec-
        retary of Agriculture with a copy of such regulation. If the
        Secretary comments  in  writing to the  Administrator re-
        garding any such regulation within 30 days after receiving
        it, the Administrator shall publish in the Federal Register
        (with the proposed regulation) the  comments of the Sec-
        retary and the response of the Administrator with  regard

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 91	FIFRA	Sec. 25

        to the Secretary's  comments.  If the Secretary does  not
        comment in  writing to the Administrator  regarding  the
        regulation within 30 days after receiving it, the Adminis-
        trator may sign such regulation for publication in the Fed-
        eral Register any time  after such 30-day period notwith-
        standing the foregoing 60-day time requirement.
            (B) FINAL  REGULATIONS.—At  least 30  days prior to
        signing any regulation in final form  for publication in  the
        Federal Register, the Administrator shall provide the Sec-
        retary of Agriculture with a copy of such regulation.  If the
        Secretary comments in writing to the  Administrator  re-
        garding any such final regulation within 15 days after re-
        ceiving it, the Administrator shall publish in the Federal
        Register  (with  the  final regulation)  the comments  of  the
        Secretary, if requested by the  Secretary, and the response
        of the Administrator concerning the Secretary's comments.
        If the Secretary does not comment in writing  to the Ad-
        ministrator regarding the regulation within 15 days after
        receiving it, the Administrator may sign such regulation
        for publication  in the Federal Register at any time after
        such  15-day period notwithstanding the foregoing 30-day
        time  requirement. In taking any  final  action under this
        subsection, the Administrator shall  include among  those
        factors to be taken into account the effect of the regulation
        on production and prices of agricultural commodities,  re-
        tail food prices, and otherwise on the  agricultural economy,
        and the  Administrator shall publish in the Federal Reg-
        ister an analysis of such effect.
            (C) TIME REQUIREMENTS.—The time requirements im-
        posed by subparagraphs (A) and  (B) may  be  waived  or
        modified  to the extent agreed upon by  the  Administrator
        and the Secretary.
            (D) PUBLICATION IN THE FEDERAL REGISTER.—The Ad-
        ministrator shall, simultaneously with any  notification to
        the Secretary of Agriculture under this paragraph prior to
        the issuance  of any proposed  or final regulation, publish
        such notification in the Federal Register.
        (3) CONGRESSIONAL  COMMITTEES.—At such time as the Ad-
    ministrator is required under paragraph  (2) of this subsection
    to provide the Secretary of Agriculture with a copy of proposed
    regulations and a copy of the final  form of regulations, the Ad-
    ministrator shall also furnish a copy of such regulations to the
    Committee on Agriculture of the House of Representatives and
    the Committee on Agriculture,  Nutrition, and Forestry  of the
    Senate.
        (4)  CONGRESSIONAL REVIEW  OF REGULATIONS.—Simulta-
    neously with  the promulgation of any rule or regulation under
    this Act, the Administrator shall transmit a copy thereof to the
    Secretary  of  the Senate and the Clerk of the House of Rep-
    resentatives.  The rule or regulation shall not become effective
    until the passage of 60 calendar days after the rule or regula-
    tion is so transmitted.
    (b) EXEMPTION OF  PESTICIDES.—The Administrator may  ex-
empt from the requirements of this Act by regulation any pesticide

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Sec. 25	FIFRA	92

which  the  Administrator determines either (1) to be  adequately
regulated by another Federal agency, or (2) to be of a character
which is unnecessary to be subject to this Act in order to carry out
the purposes of this Act.
    (c)  OTHER  AUTHORITY.—The Administrator, after  notice and
opportunity for hearing, is authorized—
        (1) to declare a pest any form of plant or animal life (other
    than man and other than bacteria, virus, and other micro-orga-
    nisms on or in living man or other living animals) which is in-
    jurious to health or the environment;
        (2) to  determine any pesticide  which contains any sub-
    stance or substances in quantities highly toxic to man;
        (3) to establish standards (which shall be consistent with
    those established under the authority of the Poison Prevention
    Packaging Act (Public Law 91-601)) with respect to the pack-
    age, container, or  wrapping in which a pesticide or device is
    enclosed for use or consumption, in order to  protect children
    and adults from serious injury or illness resulting from acci-
    dental ingestion or contact with pesticides or devices regulated
    by this Act as well as to accomplish the other purposes of this
    Act;
        (4) to specify those classes of devices which shall be subject
    to  any provision of paragraph 2(q)(l)  or section 7  of this Act
    upon the Administrator's  determination that  application of
    such provision is necessary to effectuate the purposes of this
    Act;
        (5) to prescribe regulations  requiring any pesticide to be
    colored or discolored if the Administrator determines that such
    requirement is feasible and is necessary for the protection of
    health  and the environment; and
        (6) to determine and establish suitable names to  be used
    in  the ingredient statement.
    (d) SCIENTIFIC ADVISORY PANEL.—
        (1) IN GENERAL.—The Administrator shall submit to an ad-
    visory panel for comment as to  the impact  on health  and the
    environment of the action proposed in notices of intent issued
    under section 6(b)  and of the proposed and final form of regula-
    tions issued under section 25(a) within the  same time periods
    as provided for the comments of the Secretary of Agriculture
    under such sections. The time requirements for notices of in-
    tent and proposed and final forms  of regulation may not be
    modified or waived unless in addition to meeting the  require-
    ments of section 6(b) or 25(a), as  applicable, the advisory panel
    has failed to comment on the proposed action within  the pre-
    scribed time period or has agreed to the modification or waiver.
    The Administrator shall also solicit  from the advisory panel
    comments, evaluations,  and recommendations  for operating
    guidelines to improve the effectiveness and quality  of scientific
    analyses made by personnel of the Environmental Protection
    Agency that lead to decisions by  the Administrator in  carrying
    out the provisions  of this Act. The comments,  evaluations, and
    recommendations  of the advisory panel submitted under this
    subsection  and the response of the Administrator shall be pub-
    lished in the Federal Register in  the same manner as provided

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93	FIFRA	Sec. 25

    for publication of the comments of the Secretary of Agriculture
    under such sections. The chairman of the advisory panel, after
    consultation with  the Administrator,  may  create  temporary
    subpanels on specific  projects to assist the full advisory panel
    in expediting and preparing its  evaluations,  comments,  and
    recommendations.  The  subpanels may be  composed of sci-
    entists other than members of the advisory panel, as deemed
    necessary for the purpose of evaluating scientific studies relied
    upon by the Administrator with respect  to proposed action.
    Such additional scientists  shall be  selected by the  advisory
    panel. The panel referred to in this subsection shall consist of
    7 members appointed by the Administrator from a list of 12
    nominees, 6 nominated by the National Institutes of Health
    and 6 by the National Science Foundation, utilizing a system
    of staggered terms of appointment. Members of the panel shall
    be selected on the basis of their professional  qualifications to
    assess the effects of the impact of pesticides  on health and the
    environment. To the extent feasible to insure multidisciplinary
    representation, the panel membership shall include representa-
    tion  from  the  disciplines  of toxicology,  pathology,  environ-
    mental biology,  and related sciences. If a vacancy occurs on the
    panel due to expiration of a term, resignation, or any other
    reason,  each replacement shall  be selected by  the Adminis-
    trator from a group of 4 nominees, 2 submitted by each of the
    nominating entities named  in this subsection. The Adminis-
    trator may extend the term of a panel member until the new
    member is appointed  to fill the vacancy.  If a vacancy occurs
    due to  resignation, or reason other than expiration of a term,
    the Administrator shall appoint a member to serve during the
    unexpired term  utilizing the nomination  process set forth in
    this subsection.  Should  the list of nominees  provided under
    this subsection be unsatisfactory,  the  Administrator may re-
    quest an additional set  of nominees from the nominating enti-
    ties. The Administrator may require such information from the
    nominees  to the advisory panel as the Administrator deems
    necessary, and the Administrator shall publish in the Federal
    Register  the  name, address,  and professional affiliations of
    each nominee.  Each  member of the panel shall receive per
    diem compensation at a rate not in excess of that fixed for GS-
    18 of the General Schedule  as may be determined by the Ad-
    ministrator, except that any such member who holds another
    office or position under the Federal Government the compensa-
    tion for which  exceeds such rate may elect  to receive com-
    pensation at the rate  provided for such other office or position
    in lieu of the compensation provided  by this subsection. In
    order to assure the objectivity of the advisory panel, the Ad-
    ministrator shall promulgate regulations regarding conflicts of
    interest with respect  to the members of the panel. The advi-
    sory panel established under this section  shall be permanent.
    In performing the functions assigned  by  this Act, the panel
    shall consult and coordinate its activities with the Science Ad-
    visory Board established under the  Environmental Research,
    Development, and Demonstration Authorization Act  of 1978.
    Whenever the Administrator exercises authority under section

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Sec. 26	FIFRA	94

    6(c) of this Act to immediately suspend the registration of any
    pesticide to  prevent an imminent hazard, the Administrator
    shall promptly submit to the advisory panel for comment, as
    to the impact on health and the environment, the action taken
    to suspend the registration of such pesticide.
        (2)  SCIENCE REVIEW  BOARD.—There  is  established  a
    Science  Review Board to consist of 60 scientists who shall be
    available to  the  Scientific Advisory Panel to assist in reviews
    conducted by the Panel. Members  of the  Board shall be  se-
    lected in the same manner as members of temporary subpanels
    created  under paragraph (1). Members of the Board shall be
    compensated in the same manner as members of the Panel.
    (e) PEER REVIEW.—The Administrator shall, by written proce-
dures, provide for peer review with respect to the design, protocols,
and conduct of major scientific studies conducted under this Act by
the Environmental Protection  Agency  or by  any other Federal
agency,  any  State or  political subdivision thereof, or any institution
or individual under grant, contract, or cooperative  agreement from
or with  the  Environmental Protection Agency. In such procedures,
the Administrator shall also provide for peer review, using the ad-
visory panel established under subsection (d) of this section or ap-
propriate experts appointed by the Administrator from a  current
list of nominees  maintained by such panel, with respect to the re-
sults of any  such scientific studies relied upon by the Administrator
with respect to actions the Administrator  may take relating to the
change  in classification, suspension, or cancellation of a pesticide.
Whenever the Administrator determines that circumstances do not
permit the peer  review of the results of any such scientific study
prior to the  Administrator's exercising authority under section 6(c)
of this Act to immediately suspend the registration of any pesticide
to prevent an imminent hazard, the Administrator shall promptly
thereafter provide for the conduct of peer review as provided in this
sentence. The  evaluations and relevant documentation constituting
the peer review  that relate to the proposed scientific  studies and
the results of the completed scientific studies shall be included in
the submission for comment forwarded by the Administrator to the
advisory panel as provided in subsection  (d). As used  in this sub-
section, the  term "peer review" shall mean an independent evalua-
tion by scientific  experts,  either within  or outside the Environ-
mental Protection Agency, in the appropriate disciplines.
SEC. 26.  [136w-l] STATE PRIMARY ENFORCEMENT RESPONSIBILITY.
    (a)  IN GENERAL.—For  the purposes of this Act, a  State shall
have primary enforcement responsibility for pesticide use violations
during  any  period for which the Administrator determines that
such State—
        (1)  has  adopted adequate pesticide use laws  and regula-
    tions, except that the Administrator  may not require a State
    to have pesticide use laws that are more stringent than this
    Act;
        (2)  has adopted and  is implementing adequate procedures
    for  the enforcement of such State laws and regulations; and

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 95	FIFRA	Sec. 26

        (3) will keep such records and make such reports showing
    compliance with paragraphs  (1) and (2) of this subsection as
    the Administrator may require by regulation.
    (b) SPECIAL RULES.—Notwithstanding the provisions  of sub-
 section (a) of this section, any State that enters into a cooperative
 agreement with the Administrator under section 23 of this Act for
 the enforcement of pesticide use restrictions shall have the primary
 enforcement responsibility for pesticide use  violations. Any State
 that has a plan approved by the Administrator in accordance with
 the requirements of section  11 of this Act that the Administrator
 determines meets the criteria  set out in subsection (a) of this sec-
 tion shall have the primary enforcement responsibility for pesticide
 use violations.  The Administrator shall make such determinations
 with respect to State plans  under section 11 of this Act in effect
 on the date of enactment of the Federal Pesticide Act of 1978 not
 later than six months after that date.
    (c) ADMINISTRATOR.—The Administrator shall have primary en-
 forcement responsibility for those States that do not have primary
 enforcement responsibility under this  Act.  Notwithstanding  the
 provisions of section 2(e)(l) of this Act, during any period when the
 Administrator has such enforcement responsibility, section  8(b) of
 this Act shall apply to the books and records of commercial applica-
 tors and to any applicator who holds or applies pesticides,  or uses
 dilutions of pesticides, only to provide a service of controlling pests
 without delivering any unapplied pesticide to any person so served,
 and section 9(a) of this  Act shall apply to  the establishment or
 other place where pesticides or devices are held for application by
 such persons with respect to pesticides or devices held for such ap-
 plication.
 SEC. 27. [136w-2] FAILURE BY THE STATE TO ASSURE ENFORCEMENT
           OF STATE PESTICIDE USE REGULATIONS.
    (a)  REFERRAL.—Upon receipt of any complaint or other infor-
 mation alleging or indicating a significant violation of the pesticide
 use provisions of this Act, the Administrator shall refer the matter
 to the appropriate State officials for their investigation of the mat-
 ter  consistent with the requirements of this Act. If, within thirty
 days, the State has not commenced appropriate enforcement  action,
 the Administrator may act upon the complaint or information to
 the extent authorized under this Act.
    (b)  NOTICE.—Whenever  the  Administrator determines  that a
 State having primary enforcement responsibility for pesticide use
 violations is not carrying out (or cannot carry out due to the lack
 of adequate legal authority) such responsibility, the Administrator
 shall notify the State. Such notice shall specify those aspects of the
 administration  of the State program that are determined to be in-
 adequate. The State shall have ninety days after receipt of the no-
 tice to correct any deficiencies. If after that time the Administrator
 determines  that the State program  remains inadequate, the Ad-
 ministrator may rescind, in whole or in part, the State's primary
 enforcement responsibility for pesticide use violations.
    (c) CONSTRUCTION.—Neither section 26 of this Act nor this sec-
tion shall limit  the  authority of the Administrator to enforce this
Act, where  the Administrator determines that emergency  condi-
tions exist that require immediate action on the part of the Admin-

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Sec. 28	FIFRA	96

istrator and the State authority is unwilling or unable adequately
to respond to the emergency.
SEC. 28. [136w-3] IDENTIFICATION OF PESTS; COOPERATION WITH DE-
          PARTMENT OF AGRICULTURE'S PROGRAM.
    (a) IN GENERAL.—The Administrator, in coordination with the
Secretary of Agriculture, shall identify those  pests that must be
brought under control. The Administrator shall also coordinate and
cooperate with the  Secretary of Agriculture's  research and imple-
mentation programs to develop and improve the safe use and effec-
tiveness of chemical, biological, and alternative methods to combat
and control  pests that reduce the quality and economical produc-
tion and distribution of agricultural products  to domestic and for-
eign consumers.
    (b) PEST CONTROL AVAILABILITY.—
        (1)  IN  GENERAL.—The Administrator,  in cooperation with
    the Secretary of Agriculture, shall identify—
            (A) available methods  of pest  control by crop or  ani-
        mal;
            (B) minor pest control problems,  both in minor crops
        and minor or localized problems in major crops; and
            (C) factors limiting the availability of specific pest con-
        trol methods, such as resistance to control methods  and
        regulatory actions limiting the availability of control meth-
        ods.
        (2)  REPORT.—The Secretary of Agriculture shall, not later
    than 180  days  after the  date of enactment  of this  subsection
    and annually thereafter,  prepare a report  and send the report
    to the Administrator. The report shall—
            (A) contain the information described in paragraph (1)
        and the information  required by section 1651 of the Food,
        Agriculture, Conservation, and Trade Act of 1990;
            (B) identify the crucial pest  control needs where a
        shortage of control methods is indicated by the information
        described in paragraph (1); and
            (C) describe in detail  research and extension efforts
        designed to address  the needs identified in subparagraph
        (B).
    (c)  INTEGRATED PEST MANAGEMENT.—The  Administrator, in
cooperation  with   the  Secretary  of  Agriculture, shall develop
approaches  to the control of pests  based on integrated pest  man-
agement that respond to the needs of producers,  with a special em-
phasis on minor pests.
    (d) PUBLIC HEALTH PESTS.—The Administrator, in coordination
with the Secretary  of Agriculture and the Secretary of Health and
Human Services, shall identify pests of significant public health
importance  and, in  coordination with the Public Health Service, de-
velop and implement programs  to  improve and facilitate the safe
and necessary use of chemical, biological,  and other methods to
combat and control such pests of public health  importance.
SEC. 29. [136w-i] ANNUAL REPORT.
    The Administrator shall  submit an annual report to Congress
before February 16 of each year and the first report shall be due
February 15, 1979.  The report shall include the total number of ap-

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97	FIFRA	Sec. 32

plications for conditional registration under sections 3(c)(7)(B) and
3(c)(7)(C) of this Act that were filed during the immediately preced-
ing fiscal year,  and, with respect to those  applications approved,
the Administrator shall report the Administrator's findings in each
case, the conditions imposed and any modification of such condi-
tions in each case, and the quantities produced of such pesticides.
SEC. 30. [136w-5] MINIMUM REQUIREMENTS FOR TRAINING OF MAIN-
           TENANCE APPLICATORS AND SERVICE TECHNICIANS.
    Each State may establish minimum requirements for training
of maintenance  applicators and service technicians. Such training
may include instruction in the safe and effective handling and use
of pesticides in accordance  with the  Environmental Protection
Agency approved labeling, and instruction in integrated pest man-
agement techniques. The authority  of the Administrator with re-
spect to minimum requirements for training of maintenance appli-
cators  and service technicians shall be limited to  ensuring that
each State understands the provisions of this section.
SEC. 31. [136w-6] ENVIRONMENTAL PROTECTION AGENCY MINOR USE
           PROGRAM.
    (a) The Administrator shall assure coordination of minor use
issues  through the establishment of a minor use program within
the Office of Pesticide Programs.  Such office shall be responsible
for coordinating the development of  minor use programs and poli-
cies and consulting with growers regarding minor use issues and
registrations and amendments which are submitted to the Environ-
mental Protection Agency.
    (b) The Office of Pesticide Programs shall prepare a public re-
port concerning the progress made  on the registration of minor
uses, including implementation of the exclusive use as an incentive
for registering new minor uses, within 3 years of the passage of the
Food Quality Protection Act of 1996.
SEC. 32. [136w-7] DEPARTMENT OF AGRICULTURE MINOR USE PRO-
           GRAM.
    (a) IN GENERAL.—The Secretary of Agriculture (hereinafter in
this section referred to  as the "Secretary") shall assure the coordi-
nation of the responsibilities of the  Department of Agriculture re-
lated to minor uses of pesticides, including—
        (1) carrying out the Inter-Regional Project Number 4 (IR-
    4)  as described in  section  2 of  Public Law 89-106 (7 U.S.C.
    450i(e)) and the national pesticide  resistance monitoring pro-
    gram established under section  1651  of the Food, Agriculture,
    Conservation, and Trade Act of 1990 (7 U.S.C. 5882);
        (2) supporting integrated pest management research;
        (3) consulting with growers to develop data for minor uses;
    and
        (4) providing assistance for  minor use registrations, toler-
    ances,  and reregistrations with  the Environmental Protection
    Agency.
    (b)(l) MINOR USE PESTICIDE DATA.—
        (A) GRANT AUTHORITY.—The Secretary,  in consultation
    with the Administrator, shall establish a  program to  make
    grants for the development of data to support minor use pes-
    ticide registrations and  reregistrations. The amount of any

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Sec. 33	FIFRA	98

    such grant shall  not exceed  Vz  of the cost of the project for
    which the grant is made.
        (B) APPLICANTS.—Any person who wants to develop data to
    support minor use pesticide  registrations and reregistrations
    may apply for a grant under subparagraph (A).  Priority shall
    be given to an applicant for such a grant who does not directly
    receive funds from the sale of pesticides registered for minor
    uses.
        (C) DATA OWNERSHIP.—Any  data that is developed under
    a grant under subparagraph  (A) shall be jointly  owned by the
    Department of Agriculture and  the person who received the
    grant. Such a person shall enter into an agreement with the
    Secretary under which such person shall share any fee paid to
    such person under section 3(c)(l)(F).
    (2) MINOR USE PESTICIDE DATA REVOLVING FUND.—
        (A) ESTABLISHMENT.—There is established in the Treasury
    of the United States a revolving fund to be known as the Minor
    Use Pesticide Data Revolving Fund. The Fund shall be avail-
    able without fiscal year limitation to carry out the authorized
    purposes of this subsection.
        (B) CONTENTS OF THE FUND.—There shall be deposited in
    the Fund—
            (i) such  amounts as  may be appropriated to support
        the purposes of this subsection; and
            (ii) fees collected by the Secretary for any data devel-
        oped under a grant under paragraph (1)(A).
        (C) AUTHORIZATIONS OF  APPROPRIATIONS.—There are au-
    thorized to be appropriated for each fiscal year to carry out the
    purposes  of this  subsection  $10,000,000 to  remain available
    until expended.
SEC. 33. r 136x1 SEVERABILITY.
    If any provision of this Act or the application thereof to any
person or circumstance is held invalid, the invalidity shall not af-
fect other provisions  or applications of this Act which can be given
effect without regard to the invalid provision or application, and to
this end the provisions of this Act are severable.
SEC. 34. [136y] AUTHORIZATION FOR APPROPRIATIONS.
    There is authorized  to be  appropriated to carry out this Act
(other than section 23(a))—
        (1) $83,000,000 for fiscal year  1989, of which  not more
    than  $13,735,500 shall be available for research under this
    Act;
        (2) $95,000,000 for fiscal year  1990, of which  not more
    than  $14,343,600  shall be available for research under this
    Act; and
        (3) $95,000,000 for fiscal year  1991, of which  not more
    than  $14,978,200  shall be available for research under this
    Act.

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   FEDERAL FOOD, DRUG, AND COSMETIC ACT
99

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       FEDERAL FOOD, DRUG, AND COSMETIC ACT
       (References in brackets [  ] are to title 21, United States Code)
                 CHAPTER I—SHORT TITLE
    SECTION 1. This Act may be cited as  the Federal Food, Drug,
and Cosmetic Act.
     101

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                  CHAPTER II—DEFINITIONS *

    SEC. 201.  [321] For the purposes of this Act—
    (a)(l) The term "State", except as used in the last sentence of
section 702(a), means any State or Territory of the United States,
the District of Columbia, and the Commonwealth of Puerto Rico.
    (2) The term "Territory" means  any Territory or possession of
the United States,  including the District of Columbia, and exclud-
ing the Commonwealth of Puerto Rico and the Canal Zone.
    (b) The term "interstate  commerce" means (1)  commerce be-
tween any State or Territory and any place outside thereof, and (2)
commerce within the District of Columbia or within any other Ter-
ritory not organized with a legislative body.
    (c) The term "Department" means  the Department of Health
and Human Services.
    (d) The  term "Secretary" means the  Secretary of Health and
Human Services.
    (e) The term "person" includes individual, partnership, corpora-
tion, and association.
    (f)  1The term "food" means (1) articles used for food  or drink
for man or other animals, (2) chewing  gum, and (3) articles used
for components of any such article.
    (g)(l) The term "drug" means (A) articles recognized in the offi-
cial United  States  Pharmacopeia,  official Homeopathic Pharma-
copeia of the United States, or official National Formulary, or any
supplement to any of them; and (B) articles intended for use in the
diagnosis, cure,  mitigation, treatment, or prevention of disease in
man or other  animals; and (C)  articles  (other than food) intended
to affect the structure or any function of the body of man or other
animals; and (D) articles intended for use as  a  component of any
articles specified in clause (A), (B),  or (C). A food or dietary supple-
ment  for  which a  claim,  subject  to  sections  403(r)(l)(B)  and
403(r)(3)  or  sections 403(r)(l)(B) and 403(r)(5)(D), is made in ac-
cordance with the requirements of section 403(r)  is not a drug sole-
ly because the label or the labeling contains such a claim. A food,
dietary ingredient,  or dietary supplement for which a truthful and
not  misleading  statement is  made in accordance  with  section
  1 The following additional definitions applicable to this Act are provided for in other Acts:
  Butter. The Act of March 4, 1923 (21 U.S.C. 321a), defines butter as "the food product usually
known as butter, and which is made exclusively from milk or cream, or both, with or without
common salt, and with or without additional coloring matter, and containing not less than 80
per centum by weight of milk fat, all tolerances having been allowed for."
  Package. The Act of July 24, 1919 (21 U.S.C. 321b), states "The word 'package' shall include
and shall be construed to include wrapped meats inclosed in papers  or other materials as pre-
pared by the manufacturers thereof for sale."
  Nonfat Dry Milk, Milk. The Act of July 2, 1956 (21 U.S.C. 321c), defines nonfat dry milk as
"the product resulting from the removal of fat and water from milk, and contains the lactose,
milk proteins, and milk minerals in the same relative proportions as in the fresh milk from
which made. It contains not over 5 per centum by weight of moisture. The fat content is not
over IVz per centum by weight unless otherwise indicated.", and defines milk to mean sweet
milk of cows.

                                                                 102

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103	FEDERAL FOOD,  DRUB, AND  COSMETIC ACT	Sec. 201

403(r)(6) is not a drug under clause (C) solely because the label or
the labeling contains such a statement.
    (2) The term "counterfeit drug" means a drug which,  or  the
container or labeling of which, without authorization, bears  the
trademark, trade name, or other identifying mark,  imprint, or de-
vice, or any likeness thereof, of a drug manufacturer, processor,
packer, or distributor other than the person or persons who  in fact
manufactured,  processed,  packed, or  distributed such drug and
which thereby falsely purports or is represented to be the product
of, or to have been packed or  distributed by, such other drug manu-
facturer, processor, packer, or distributor.
    (h) The term "device" (except when used in paragraph (n) of
this section and in sections 301(i), 403(f), 502(c), and 602(c))  means
an  instrument, apparatus, implement, machine, contrivance,  im-
plant, in vitro reagent, or other similar or related article, including
any component, part, or accessory, which is—
        (1) recognized in the official National Formulary,  or  the
    United States Pharmacopeia, or any supplement to them,
        (2) intended for use in the  diagnosis of disease  or other
    conditions, or in the cure, mitigation, treatment, or prevention
    of disease, in man or other animals, or
        (3) intended to affect the structure or any  function of the
    body of man or other animals, and
which  does not achieve  its  primary  intended  purposes through
chemical action within or on the body of man or other animals and
which is not dependent upon being metabolized for the achieve-
ment of its primary intended  purposes.
    (i) The term  "cosmetic"  means  (1) articles  intended  to  be
rubbed, poured, sprinkled, or sprayed on, introduced into, or other-
wise applied to the human body or any part thereof for cleansing,
beautifying, promoting attractiveness,  or altering the  appearance,
and (2) articles intended for  use as a component of any such arti-
cles; except that such term shall not include soap.
    (j) The term  "official compendium" means the official United
States Pharmacopeia,  official Homeopathic Pharmacopeia  of  the
United States,  official National Formulary, or any supplement to
any of them.
    (k) The term "label"  means  a display of written, printed, or
graphic matter upon the immediate container of any article; and a
requirement made by or under authority of this Act that any word,
statement, or other information appear on the label shall  not be
considered to be  complied with unless such  word, statement, or
other information also appears on the outside container or wrapper,
if any there be, of the retail package of such article,  or is easily leg-
ible through the outside container or wrapper.
    (1) The term  "immediate container" does  not include package
liners.
    (m) The term "labeling" means  all labels and other written,
printed, or graphic matter (1) upon  any article or  any of its con-
tainers or wrappers, or (2) accompanying such article.
    (n) If an article is alleged to be misbranded because the label-
ing or advertising is misleading, then  in determining whether  the
labeling or advertising is  misleading there shall be taken into ac-
count (among other things) not only representations made or sug-

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Sec. 201	FEDERAL FOOD.  DRUG, AND COSMETIC ACT	104

gested by  statement,  word,  design,  device,  or  any combination
thereof, but also the extent  to which the labeling or advertising
fails to reveal facts material in the light of such representations or
material with respect to consequences which  may result from the
use of the article to which the labeling or advertising relates under
the conditions  of use prescribed in the labeling or advertising
thereof or under such conditions of use as are customary or usual.
    (o) The representation of a drug, in  its labeling, as an anti-
septic  shall be considered  to be a  representation  that  it  is  a
germicide,  except in the case of a drug purporting to be, or rep-
resented as, an antiseptic for inhibitory use as a wet dressing, oint-
ment, dusting powder, or such other use as involves prolonged con-
tact with the body.
    (p) The term "new drug" means—
        (1) Any drug (except a new animal drug or an animal feed
    bearing or  containing a  new animal drug) the composition of
    which  is such that such drug  is not generally recognized,
    among experts qualified by scientific training  and  experience to
    evaluate the safety and effectiveness of drugs, as safe and ef-
    fective for use under the conditions prescribed, recommended,
    or suggested in  the  labeling thereof,  except  that such a drug
    not so  recognized shall not be deemed to be a "new drug" if at
    any time prior to  the enactment of this Act  it was  subject to
    the Food and Drugs Act  of June  30, 1906, as amended, and  if
    at such time its labeling contained the same representations
    concerning the conditions of its use; or
        (2) Any drug (except a new animal drug or an animal feed
    bearing or  containing a  new animal drug) the composition of
    which is such that such  drug, as a result of investigations to
    determine its safety and effectiveness for use under such condi-
    tions, has become  so recognized,  but which has not, otherwise
    than in such investigations, been used to a material extent or
    for a material time under such conditions.
    (q)(l) The term "pesticide chemical" means any substance that
is a pesticide within the meaning of the Federal Insecticide, Fun-
gicide, and Rodenticide Act, including all active and inert ingredi-
ents of such pesticide.
    (2) The term "pesticide chemical residue" means a  residue in
or on raw agricultural commodity or processed food of—
        (A) a pesticide chemical; or
        (B) any other added  substance that is present on or in the
    commodity or food primarily as a result of the metabolism or
    other degradation of a pesticide chemical.
    (3) Notwithstanding paragraphs (1) and (2), the Administrator
may by regulation except a substance from the definition of "pes-
ticide chemical" or "pesticide  chemical residue" if—
        (A) its occurrence as a residue on or in a raw agricultural
    commodity or processed food is attributable primarily to natu-
    ral causes  or to human activities not involving the use of any
    substances for a pesticidal purpose in the production, storage,
    processing, or transportation of any raw agricultural commod-
    ity or processed food; and
        (B) the Administrator, after consultation with the  Sec-
    retary,  determines  that the substance  more  appropriately

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 105	FEDERAL FOOD, DRUB. AND  COSMETIC ACT	Sec. 201

     should be regulated under one or  more provisions of this Act
     other than sections 402(a)(2)(B) and 408.
     (r) The term "raw agricultural commodity means any food in
 its raw or natural state, including all  fruits that are washed, col-
 ored, or otherwise treated in their unpeeled natural form prior to
 marketing.
     (s) The term "food additive" means any substance the intended
 use of which results or  may reasonably be expected to result, di-
 rectly or indirectly, in its becoming a  component or otherwise af-
 fecting the characteristics of any food (including any substance in-
 tended for use in  producing, manufacturing,  packing, processing,
 preparing, treating, packaging, transporting, or holding food; and
 including any source of radiation intended for any such  use), if
 such substance is not generally recognized, among experts qualified
 by scientific training and experience to evaluate its safety,  as hav-
 ing been adequately shown through scientific procedures (or, in the
 case of a substance used in food prior to January 1, 1958, through
 either scientific procedures or  experience based on common use in
 food) to be safe under the conditions of its intended use; except that
 such term  does not include—
        (1) a pesticide chemical residue in or on a raw agricultural
    commodity or processed food; or
        (2) a pesticide chemical; or
        (3) a color additive; or
        (4) any substance used in accordance with a sanction  or
    approval granted prior to the  enactment of this paragraph1
    pursuant to this Act, the Poultry Products Inspection Act (21
    U.S.C. 451 and the following)  or the Meat Inspection  Act of
    March 4, 1907 (34 Stat. 1260), as  amended and extended (21
    U.S.C. 71 and the following);
        (5) a new animal drug; or
        (6) an  ingredient described in  paragraph (ff) in,  or in-
    tended for use in, a dietary supplement.
    (t)(D The term "color additive" means a material which—
        (A) is a dye, pigment,  or other substance made by a proc-
    ess of synthesis  or similar artifice, or extracted, isolated,  or
    otherwise  derived,  with  or  without  intermediate or final
    change of identity, from a  vegetable, animal, mineral, or other
    source, and
        (B) when added or applied  to a food, drug,  or cosmetic,  or
    to the human  body  or any part thereof, is capable (alone  or
    through  reaction with other  substance)  of imparting color
    thereto;
except that such term does not include any material which the Sec-
retary, by  regulation, determines is used (or intended to be  used)
solely for a purpose or purposes other than coloring.
    (2) The term  "color"  includes  black, white, and intermediate
grays.
    (3) Nothing in subparagraph (1) of this paragraph shall be con-
strued to apply to any pesticide chemical, soil or plant nutrient,  or
other agricultural chemical solely because of its effect in aiding, re-
 1 Probably should strike out "the enactment of this paragraph" and insert "September 6,
1958,".

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Sec. 201	FEDERAL FOOD, DRUG, AND COSMETIC ACT	106

tarding, or otherwise affecting, directly or indirectly, the growth or
other natural physiological processes of produce of the soil and
thereby affecting its color, whether before or after harvest.
    (u) The term "safe," as used in  paragraph (s) of this section
and in sections 409, 512, and 721, has reference to the health of
man or animal.
    (v) The term "new animal drug" means any drug intended for
use for animals other than man, including any drug intended for
use in animal feed but not including such animal feed—
        (1) the composition of which  is such that such drug is not
    generally recognized,  among experts  qualified  by  scientific
    training  and experience to  evaluate the  safety and  effective-
    ness of animal  drugs,  as safe and effective for use under the
    conditions prescribed, recommended, or suggested in the label-
    ing thereof; except that such a drug not so recognized shall not
    be deemed to be a "new animal  drug" if at any time prior to
    June 25, 1938, it was subject to the Food and Drug Act of June
    30,  1906, as amended, and if at such time its  labeling con-
    tained the same representations concerning the conditions of
    its use; or
        (2) the composition of which is such  that such drug,  as a
    result of investigations to determine its  safety and  effective-
    ness for  use under such conditions, has become so recognized
    but which has not, otherwise than in such investigations,  been
    used to a material extent or for a material time under  such
    conditions.
    (w) The term "animal feed", as used in paragraph (w)1 of this
section, in section 512, and in  provisions of this Act referring to
such paragraph or section, means an article which is intended for
use for food for animals other than man and which is intended for
use as a substantial source of nutrients in the diet of the animal,
and is not limited to a mixture intended to  be the sole ration of
the animal.
    (x) The term "informal hearing" means a hearing which is not
subject to section 554, 556, or 557 of title  5  of the United States
Code and which provides for the following:
        (1) The presiding officer in the hearing shall be designated
    by the Secretary from officers and employees of the Depart-
    ment who have not participated in any action of the Secretary
    which is the subject of the hearing and who are not directly re-
    sponsible to an officer or employee of the Department who has
    participated in any such action.
        (2) Each party to the hearing shall have the right at all
    times to  be advised and accompanied by an attorney.
        (3) Before the hearing,  each party to the hearing shall be
    given reasonable notice of the matters to be considered at the
    hearing, including a comprehensive statement of the basis for
    the action taken or proposed by the Secretary which is the sub-
    ject  of the hearing and a  general summary of the information
    which will be presented by the Secretary at the hearing in sup-
    port of such action.
  *So in original. Probably should be paragraph "(v)".

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107	FEDERAL FOOD. DRUB, AND COSMETIC ACT	Sec. 201

        (4) At the hearing the parties to the hearing shall have the
    right to hear a full and complete statement of the action of the
    Secretary which is the subject of the hearing together with the
    information and  reasons  supporting  such action, to conduct
    reasonable questioning, and to present any oral or written in-
    formation relevant to such action.
        (5) The presiding officer in  such  hearing  shall prepare a
    written report of the hearing to which shall  be attached all
    written material presented at the hearing. The participants in
    the hearing shall be given the opportunity to  review and cor-
    rect or supplement the presiding officer's report of the hearing.
        (6) The Secretary may require the hearing to be  tran-
    scribed. A party to the hearing shall have the right to have the
    hearing transcribed  at  his expense.  Any transcription of a
    hearing shall be included in the presiding officer's report of the
    hearing.
    (y)  The term "saccharin"  includes calcium saccharin,  sodium
saccharin, and ammonium saccharin.
    (z) The term "infant  formula" means a food which purports to
be or is represented for special dietary use solely as a food for in-
fants by reason of its simulation of  human milk or its suitability
as a complete or partial substitute for human milk.
    (aa) The term "abbreviated drug application" means an appli-
cation submitted under section 505(j) or 507 for the  approval of a
drug that relies on the approved application of another drug with
the same  active ingredient to establish safety and efficacy, and—
        (1) in the case of section 306, includes a supplement to
    such an application for a different or additional use of the drug
    but does not include a supplement to such an application for
    other than a different or additional use of the drug, and
        (2) in the case of sections 307 and 308, includes any sup-
    plement to such an application.
    (bb) The term  "knowingly" or "knew" means that a  person,
with respect to information—
        (1) has actual knowledge of the information, or
        (2) acts in deliberate ignorance or  reckless  disregard of the
    truth or falsity of the information.
    (cc) For purposes of section  306, the term  "high managerial
agent"—
        (1) means—
            (A) an officer or director  of a corporation or an associa-
        tion,
            (B) a partner of a partnership, or
            (C) any employee or other agent of a corporation, asso-
        ciation, or partnership,
    having duties such that the  conduct of such officer, director,
    partner, employee, or agent may fairly be assumed to represent
    the  policy of the corporation,  association,  or partnership, and
        (2) includes  persons  having management  responsibility
    for—
            (A) submissions to the Food and Drug Administration
        regarding the development or approval of any drug prod-
        uct,

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Sec. 201	FEDERAL FOOD, DRUG, AND COSMETIC ACT	108

            (B) production, quality assurance, or quality control of
        any drug product, or
            (C) research and development of any drug product.
    (dd) For purposes of sections 306 and 307, the term "drug prod-
uct" means a drug subject to regulation under section 505, 507,
512, or 802 of this Act or under section 351 of the Public Health
Service Act.
    (ee) The  term "Commissioner" means  the  Commissioner of
Food and Drugs.
    (ff) The term "dietary supplement"—
        (1) means a product (other than tobacco) intended to sup-
     Element the diet that bears or contains one or more of the fol-
     )wing dietary ingredients:
            (A) a vitamin;
            (B) a mineral;
            (C) an herb or other botanical;
            (D) an amino acid;
            (E) a dietary substance for use by man to supplement
        the diet by increasing the total dietary intake; or
            (F) a  concentrate, metabolite, constituent, extract, or
        combination of any ingredient described in clause (A), (B),
        (C), (D), or (E);
        (2) means a product that—
            (A)(i) is intended for ingestion in a form described in
        section 411(c)(l)(B)(i); or
            (ii) complies with section 411(c)(l)(B)(ii);
            (B) is not represented for use as a  conventional food
        or as a sole item of a meal or the diet; and
            (C) is labeled as a dietary  supplement;  and
        (3) does—
            (A) include an article that is approved as a new drug
        under section 505, certified as an antibiotic  under section
        507, or licensed as a biologic under section 351 of the Pub-
        lic Health Service Act  (42 U.S.C. 262) and  was, prior to
        such approval, certification, or license, marketed as a die-
        tary supplement or as a food  unless the Secretary has is-
        sued a regulation, after notice and comment, finding that
        the article, when used as or in a dietary supplement under
        the conditions of use  and dosages set forth in the labeling
        for such dietary supplement, is unlawful under section
        402(f); and
            (B) not include—
                (i) an article that is approved as a  new drug under
            section 505,  certified as  an antibiotic under section
            507, or licensed as  a biologic under section 351 of the
            Public Health Service Act (42 U.S.C. 262), or
                (ii)  an article  authorized  for investigation as a
            new  drug, antibiotic, or biological for which  substan-
            tial clinical investigations have been instituted and for
            which the existence  of such investigations  has been
            made public,
    which was not before such approval, certification, licensing, or
    authorization marketed as  a  dietary supplement or as a food
    unless the Secretary, in the Secretary's discretion, has issued

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109	FEDERAL FOOD. DRUB, AND COSMETIC ACT	Sec. 201

    a regulation, after notice and comment, finding that the article
    would be lawful under this Act.
Except for purposes of section 20 Kg), a dietary supplement shall be
deemed to be a food within the meaning of this Act.
    (gg) The term "processed food" means any food other than a
raw agricultural commodity and includes any raw agricultural com-
modity that has been subject to processing, such as canning, cook-
ing, freezing, dehydration, or milling.
    (hh) The term "Administrator" means the Administrator of the
United States Environmental Protection Agency.

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     CHAPTER HI—PROHIBITED ACTS AND PENALTIES

                        PROHIBITED ACTS

    SEC. 301. [331] The following acts and the causing thereof are
hereby prohibited:
    (a) The introduction or delivery for introduction into interstate
commerce of any  food,  drug, device, or cosmetic that is adulterated
or misbranded.
    (b) The adulteration or misbranding of any food, drug, device,
or cosmetic in interstate commerce.
    (c) The receipt in interstate commerce of any food, drug, device,
or cosmetic that is  adulterated or misbranded, and the delivery or
proffered delivery thereof for pay or otherwise.
    (d) The introduction or delivery for introduction into interstate
commerce of any article in violation of section 404 or 505.
    (e) The refusal to permit access to or copying of any  record as
required by section 412, 504, or 703; or the failure  to establish or
maintain any record, or make any report,  required under section
412, 504, 505 (i) or (k), 507(d) or (g), 512(a)(4)(C), 512 (j), (1) or (m),
515(f), or 519 or  the refusal to  permit access to or verification or
copying of any such required record.
    (f) The refusal to permit entry or inspection as authorized by
section 704.
    (g) The manufacture within any Territory of any food, drug, de-
vice, or cosmetic that is adulterated or misbranded.
    (h) The giving of a guaranty or undertaking referred to in sec-
tion 333(c)(2) of this title which guaranty or undertaking is false,
except by a person who relied upon a guaranty or undertaking to
the same effect signed  by, and containing the name and address of,
the person residing in the United States from whom he received in
good faith  the food, drug, device,  or cosmetic; or the giving of a
guaranty or undertaking referred to in section 333(c)(3) of this title
which guaranty or undertaking is false.
    (i)(l) Forging, counterfeiting,  simulating, or falsely represent-
ing, or without proper  authority using any mark, stamp, tag, label,
or other identification device authorized or required by regulations
promulgated under the provisions of section 404, 506, 507, or 721.
    (2) Making, selling, disposing of, or keeping in possession, con-
trol, or custody, or concealing any punch, die, plate, stone, or other
thing designed to print, imprint, or reproduce the trademark, trade
name, or other identifying mark,  imprint, or device of another or
any likeness of any of the foregoing upon any drug or container or
labeling thereof so as to render such drugs a counterfeit drug.
    (3) The doing of any act which causes a drug to be a counter-
feit drug, or the  sale or dispensing, or the  holding for sale or dis-
pensing, of a counterfeit drug.
                                                             110

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Ill	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 301

    (j) The using by any person to his own advantage, or revealing,
other than to the Secretary or officers or employees of the Depart-
ment,  or to  the courts when  relevant in any judicial proceeding
under this Act, any information acquired under authority of section
404, 409, 412, 505, 506, 507, 510, 512, 513, 514, 515, 516, 518, 519,
520, 704, 708, or 721 concerning any method or process which as
a trade secret is entitled to protection; or the violating of section
408(i)(2) or any regulation issued under that section..l This  para-
graph does not authorize the  withholding of information  from ei-
ther House of Congress or from, to the extent of matter within its
jurisdiction,  any committee or subcommittee of such committee or
any joint committee of Congress or any subcommittee of such joint
committee.
    (k) The  alteration, mutilation, destruction, obliteration, or re-
moval of the whole or any part of the labeling of, or the  doing of
any other act with respect to, a  food, drug,  device, or cosmetic, if
such act is done while such article is held for sale (whether or not
the first sale) after shipment in interstate commerce and results in
such article being adulterated or misbranded.
    (1) The using,  on  the labeling of any  drug or device or in any
advertising relating to such drug or device,  of any representation
or suggestion that approval of an application with respect to such
drug or device is in effect under section 505, 515, or 520(g), as the
case may be, or that such drug or device complies with the provi-
sions of such section.
    (m) The  sale or offering for sale of colored oleomargarine or col-
ored  margarine,  or the possession or serving  of colored  oleo-
margarine or colored margarine  in violation of section 407(b) or
407(c).
    (n) The using, in labeling, advertising or other sales promotion
of any reference to any report or analysis furnished in compliance
with section  704.
    (o) In the case of a prescription drug  distributed or offered for
sale in interstate commerce, the failure of the manufacturer,  pack-
er,  or  distributor  thereof to maintain for  transmittal, or to trans-
mit, to any practitioner licensed by applicable State law to admin-
ister such drug who makes  written request for information  as to
such drug, true and correct copies of all printed matter which  is re-
quired to be  included in any package in which that drug is distrib-
uted or sold, or such other printed matter as is  approved by the
Secretary. Nothing in this paragraph shall be construed to exempt
any person  from  any labeling requirement  imposed by  or under
other provisions of this Act.
    (p) The failure to register in accordance with section  510, the
failure to provide  any information required by section  510(j) or
510(k); or the  failure to provide  a  notice  required  by  section
510QX2).
    (q)(l) The failure or refusal  to (A) comply with any require-
ment prescribed under section  518 or 520(g),  (B) furnish any notifi-
cation or other material or information required by or under sec-
  'So in original. See the amendment made by section 403 of Public Law 104-170 (110 Stat.
1514).

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Sec. 302	FEDERAL  FOOD. DRUE, AND COSMETIC ACT	112

tion 519 or 520(g), or (C) comply with a requirement under section
522.
    (2) With  respect to any device, the submission of any report
that is required by or under this Act that is false or misleading in
any material respect.
    (r) The movement  of a  device in violation of an  order under
section 304(g) or the removal or alteration of any mark or label re-
quired by the order to identify the device as  detained.
    (s) The failure to provide the notice required by section 412(c)
or  412(e), the failure  to  make the reports required by  section
412(f)(l)(B), the  failure to retain  the records required by section
412(b)(4), or the  failure to meet the requirements prescribed under
section 412(0(3).
    (t) The importation of a drug in violation of section 801(d)(l),
the sale, purchase, or trade  of a drug or drug sample or the offer
to sell, purchase, or trade a drug or drug sample  in violation of sec-
tion 503(c), the sale, purchase, or trade of a coupon, the offer to
sell, purchase, or trade  such  a coupon, or the counterfeiting of such
a coupon in violation of section 503(c)(2), the distribution of a drug
sample in violation  of  section 503(d) or the failure to otherwise
comply with the requirements of section 503(d), or the distribution
of drugs in violation of section 503(e) or the failure to otherwise
comply with the requirements of section 503(e).
    (u)1 The  failure  to  comply with any requirements  of the provi-
sions of, or any  regulations  or orders of the Secretary, under sec-
tion 512(a)(4)(A), 512(a)(4)(D), or 512(a)(5).
    (v) The introduction or delivery for introduction into interstate
commerce of a dietary supplement that is unsafe  under section 413.
    (w) The making of a knowingly false statement in any record
or report required or requested under subparagraph (A) or (B) of
section 801(d)(3), the failure to submit or maintain records as re-
quired by sections 801(d)(3)(A) and 801(d)(3)(B), the  release  into
interstate commerce of  any article imported into the United States
under section 801(d)(3)  or any finished product made from such ar-
ticle (except for export  in accordance with section 801(e) or 802 or
section 351(h) of the Public  Health Service Act), or the failure to
export  or  destroy any component, part or accessory not incor-
porated  into  a drug, biological product or  device that will be ex-
ported in accordance with section 801(e) or  802 or section 351(h) of
the Public Health Service Act.

                     INJUNCTION PROCEEDINGS

    SEC. 302. [332]  (a) The district courts of the United States and
the United States courts of  the Territories  shall have jurisdiction,
for cause shown to restrain  violations of section 301,  except para-
graphs (h), (i), and (j).
  lrThis subsection was added by section 2(bXlXB) of P.L. 103-396. Subsections (c) and (d) of
section 2 of that Act state the following:
  (c) REGULATIONS.—Not later than 2 years after the date of the enactment of this Act, the Sec-
retary of Health and Human Services shall promulgate regulations to implement paragraphs
(4)(A) and (5) of section 512(a) of the Federal Food, Drug, and Cosmetic Act (as amended by
subsection (a)).
  (d) EFFECTIVE DATE.—The amendments made by this section shall take effect upon the adop-
tion of the final regulations under subsection (c).

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 113 _ FEDERAL FOOD, DRUB, AND  COSMETIC ACT _ Sec. 303

    (b) In case of violation of an injunction or restraining order is-
 sued  under this section, which also  constitutes a violation of this
 Act, trial shall be by the court, or, upon demand of the accused, by
 a jury.

                           PENALTIES

    SEC.  303. [3333 (a)(l) Any person who  violates a provision of
 section 301 shall be imprisoned for not more than one year or fined
 not more  than $1,000, or both.
    (2) Notwithstanding the provisions of paragraph (1) of this sec-
 tion 1, if any person commits  such a violation after a conviction of
 him under this section has become final, or commits such a viola-
 tion with the intent to defraud or mislead, such person shall be im-
 prisoned  for not more than three years or fined not  more  than
 $10,000 or both.
    (b)(l) Notwithstanding subsection (a), any person who violates
 section 301(t) by—
        (A) knowingly importing a drug in violation of section
        (B) knowingly selling, purchasing, or trading a drug or
    drug  sample or knowingly offering to  sell, purchase, or trade
    a drug or drug sample, in violation of section 503(c)(l),
        (C) knowingly selling, purchasing, or trading a  coupon,
    knowingly offering to sell, purchase, or trade such a coupon, or
    knowingly counterfeiting such a coupon, in violation of section
    503(c)(2), or
        (D) knowingly distributing drugs  in violation of section
    503(e)(2)(A),
shall be imprisoned for not more than 10 years or fined not more
than $250,000, or both.
    (2) Any manufacturer or distributor who distributes drug sam-
ples by means other than the mail or common carrier whose rep-
resentative, during the course of the  representative's employment
or association with that manufacturer or distributor, violated sec-
tion 301(t) because of a violation of section 503(c)(l) or violated any
State law prohibiting the sale, purchase, or trade of a drug sample
subject to section 503(b) or the offer to sell,  purchase,  or trade such
a drug sample shall, upon conviction of the representative for such
violation,  be subject to the following civil penalties:
        (A) A civil penalty of not more than $50,000 for each of the
    first two such  violations  resulting in a conviction of any rep-
    resentative of the manufacturer or distributor in any  10-year
    period.
        (B) A  civil penalty of not more than $1,000,000 for each
    violation resulting in  a conviction of any representative after
    the second conviction in any 10-year period.
For the purposes of this paragraph, multiple convictions of one or
more persons  arising out  of the same event or transaction, or a re-
lated series of events or  transactions, shall be considered as one
violation.
    (3) Any manufacturer or distributor who violates section 301(t)
because  of a failure to  make a report  required by  section
  lThe words "of this section" should probably be stricken.

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Sec. 303	FEDERAL FOOD, DRU6, AND  COSMETIC ACT	TI4

503(d)(3)(E) shall be subject to  a civil penalty of not more  than
$100,000.
    (4)(A) If a manufacturer or distributor or any representative of
such manufacturer or distributor provides information leading to
the institution of a criminal proceeding against, and conviction of,
any representative of that manufacturer or distributor for a viola-
tion of section  301(t) because of a sale, purchase,  or trade or offer
to purchase, sell, or trade a  drug sample in  violation  of section
503(c)(l) or for a violation of State law prohibiting the sale, pur-
chase, or trade or offer to sell, purchase, or  trade a drug sample,
the conviction  of such representative  shall not be considered as a
violation for purposes of paragraph (2).
    (B) If, in an action brought under paragraph (2) against a man-
ufacturer or distributor relating to the conviction of a representa-
tive of such manufacturer or distributor for the sale,  purchase, or
trade of a  drug or the offer to sell, purchase, or trade  a drug, it
is shown, by clear and convincing evidence—
        (i) that the manufacturer or  distributor conducted, before
    the institution of a criminal proceeding against such represent-
    ative for the violation which resulted in such conviction, an in-
    vestigation of events or transactions which would have led to
    the  reporting of information leading  to  the institution of a
    criminal proceeding against, and conviction of, such represent-
    ative for such purchase, sale, or trade or offer to purchase, sell,
    or trade, or
        (ii) that, except in the case of the conviction of a represent-
    ative employed in a  supervisory function,  despite diligent im-
    plementation by the manufacturer  or distributor of an  inde-
    pendent audit and security system  designed  to detect such a
    violation, the manufacturer or distributor could not reasonably
    have been expected to have detected such violation,
the conviction  of such representative shall not be  considered as a
conviction for purposes of paragraph (2).
    (5) If a person provides information leading to the institution
of a criminal proceeding  against, and  conviction of, a person for a
violation of section 301(t) because of the sale, purchase, or trade of
a drug sample or the offer to sell, purchase, or trade a drug sample
in violation of section 503(c)(l), such person  shall be entitled to
one-half of the criminal fine imposed  and collected for such viola-
tion but  not more than $125,000.
    (c) No  person shall  be subject to the penalties of subsection
(a)(l) of this section,  (1) for having received in interstate commerce
any article  and delivered it or proffered delivery of it,  if such deliv-
ery or proffer was made  in good faith, unless he refuses to furnish
on  request of  an officer  or employee  duly designated by the Sec-
retary the  name and address of the  person from  whom he pur-
chased or received such article and copies of all documents, if any
there be, pertaining to the delivery of the article to him; or (2) for
having violated section 301(a) or (d),  if he establishes a guaranty
or undertaking signed by, and containing the name and address of,
the person residing in the United States from whom he received in
good  faith the article, to the effect, in case of an alleged violation
of  section  301(a), that  such article  is not adulterated or mis-
branded, within the  meaning of this Act,  designating this Act, or

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N5	FEDERAL FOOD. DRUB, AND COSMETIC  ACT	Sec. 303

to the effect, in case of an alleged violation of section 301(d), that
such article is not an article which  may not, under the provisions
of section 404 or 505, be introduced into interstate commerce; or (3)
for having violated  section 301(a),  where the violation exists be-
cause the article is adulterated by reason of containing a color ad-
ditive not from a batch certified in accordance with regulations pro-
mulgated by the Secretary under this Act, if  such  person estab-
lishes  a guaranty or undertaking signed by, and containing the
name and address of, the manufacturer of the color additive, to the
effect that such color additive was from a batch certified in accord-
ance with the applicable regulations promulgated by the Secretary
under this Act; or (4) for having violated section 301 (b), (c),  or (k)
by failure to comply with section 502(f) in respect to an article re-
ceived in interstate  commerce to which  neither section  503(a) nor
section 503(b)(l) is applicable, if the delivery or proffered delivery
was made in  good faith and the labeling at the time thereof con-
tained the same directions for use and warning  statements as were
contained in the labeling at the time of such receipt of such article;
or (5)  for having violated section 301(i)(2) if sucn person  acted in
good faith and had no reason to believe that use of the punch, die,
plate,  stone, or other thing involved would result in a drug being
a  counterfeit  drug, or  for having violated  section 301(i)(3) if the
person doing the act or causing it to be done  acted in good faith
and had no  reason to believe that the drug was a counterfeit drug.
    (d) No person shall be subject  to the  penalties of subsection
(a)(l) of this section for a violation of section  301 involving mis-
branded food if the violation exists  solely because the food is mis-
branded under section 403(a)(2) because of its advertising.
    (e)(l) Except as provided in paragraph (2), any person who dis-
tributes or  possesses with the  intent to  distribute any  anabolic
steriod for any use in humans other than the treatment of disease
pursuant to the order  of a physician shall be  imprisoned for not
more than three years or fined under  title 18, United States  Code,
or both.
    (2) Any person who distributes or possesses with the intent to
distribute to an individual under 18  years of age, any anabolic ster-
oid for any use in humans other than the treatment of disease pur-
suant to the order of a physician shall be imprisoned for not more
than six years or fined under title 18,  United States Code, or both.
    (f)(l) Except as provided in paragraph  (2),  whoever knowingly
distributes,  or possesses with intent to  distribute, human growth
hormone for any use in humans other than the  treatment of a dis-
ease or other  recognized medical condition,  where  such  use has
been authorized by the Secretary of Health and Human  Services
under  section  505  and pursuant to the order of a physician,  is
guilty of an offense punishable by not  more than 5 years in prison,
such fines as are authorized by title 18,  United States Code,  or
both.
    (2) Whoever commits any offense set forth in paragraph (1) and
such offense involves an individual under 18 years of age is punish-
able by not more than 10 years imprisonment, such fines as are au-
thorized by title 18, United States Code, or both.
    (3) Any conviction for a violation  of paragraphs  (1) and  (2) of
this subsection shall be considered  a felony violation of the Con-

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Sec. 303	FEDERAL FOOD, DRUB, AND COSMETIC  ACT	116

trolled Substances Act for the purposes of forfeiture under section
413 of such Act.
    (4) As used in this subsection the  term "human growth hor-
mone" means somatrem, somatropin, or an analogue  of either of
them.
    (5) The Drug Enforcement Administration is authorized  to in-
vestigate offenses punishable by this subsection.
    (g)(l)(A) Except as provided in subparagraph (B), any person
who violates a requirement of this  Act which  relates to  devices
shall be liable to the United States for a civil penalty in an amount
not to exceed $15,000 for each such violation, and not to exceed
$1,000,000 for all  such violations adjudicated in a  single proceed-
ing.
    (B) Subparagraph (A) shall not apply—
        (i) to any  person who violates the requirements of section
    519(a) or 520(f) unless such violation constitutes (I) a signifi-
    cant or knowing departure from such requirements, or  (II) a
    risk to public health,
        (ii)  to any person who commits minor violations of section
    519(e) or 519(f) (only with respect to correction reports) if such
    person demonstrates substantial compliance with such section,
    or
        (iii) to violations of section 501(a)(2)(A)  which involve one
    or more devices which are not defective.
    (2)(A) Any person who introduces into interstate commerce or
delivers for introduction into interstate commerce an article of food
that is adulterated within the meaning of section 402(a)(2)(B) shall
be subject to a civil money penalty of not more than $50,000 in the
case of an individual and $250,000 in the case of any other person
for such introduction or delivery,  not to exceed $500,000 for all
such violations adjudicated in a single proceeding.
    (B) This paragraph shall not apply to any person who grew the
article of food that is adulterated. If the Secretary assesses a civil
penalty against any person under  this paragraph,  the Secretary
may not use the criminal authorities under this section to sanction
such person for the introduction or delivery for introduction into
interstate commerce of the article of food that is adulterated.  If the
Secretary assesses a civil penalty against any person under this
paragraph, the Secretary may not use the  seizure authorities of
section 304 or the injunction authorities of section 302 with respect
to the article of food that is adulterated.
    (C) In a hearing to assess a civil penalty under this paragraph,
the presiding officer shall have  the same authority with regard to
compelling testimony or production of documents as a presiding of-
ficer has  under section 408(g)(2)(B). The third sentence  of para-
graph (3)(A) shall not apply to  any investigation under this para-
graph.
    (3)(A) A civil penalty under paragraph  (1) or (2)  shall be as-
sessed by the Secretary by an order made on the record after op-
portunity  for a hearing provided in accordance with this subpara-
graph and section 554 of title 5, United States Code. Before issuing
such an order, the Secretary shall give written notice to the person
to be assessed  a civil penalty under such order of the Secretary's
proposal to issue  such order and  provide such person an  oppor-

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117	FEDERAL  FOOD, DRUB. AND COSMETIC ACT	Sec. 304

tunity for a hearing on the order. In the course of any investiga-
tion, the Secretary may issue subpoenas requiring  the  attendance
and testimony of witnesses and the production of evidence that re-
lates to the matter under investigation.
    (B) In determining the amount of a civil penalty, the Secretary
shall take into account the nature, circumstances, extent, and grav-
ity of the violation or violations and, with respect  to the violator,
ability to pay, effect on ability to continue to do business, any his-
tory of prior such violations, the degree of culpability, and such
other matters as justice may require.
    (C) The Secretary may  compromise,  modify, or remit, with or
without conditions, any civil penalty which may be  assessed under
paragraph (1) or (2). The amount of such penalty, when finally de-
termined, or the  amount  agreed upon in compromise, may be de-
ducted from  any sums  owing by the United States to  the person
charged.
    (4) Any person who requested, in accordance with paragraph
(3)(A), a hearing respecting the assessment of a civil penalty and
who is aggrieved by an order assessing a civil penalty may  file a
petition for judicial review  of such order with the United States
Court of Appeals  for the District of  Columbia Circuit  or for any
other circuit in which such person resides  or transacts business.
Such a petition may only be filed within the 60-day period begin-
ning on the date the order making such assessment was  issued.
    (5) If any person fails to pay an assessment of a civil penalty—
        (A) after the order  making the assessment becomes  final,
    and if such  person does not file a petition for  judicial review
    of the order in accordance with paragraph (4), or
        (B) after a court in  an action brought under paragraph (4)
    has entered a final judgment in favor of the Secretary,
the Attorney General shall  recover the amount assessed (plus in-
terest at currently prevailing rates from the  date of the expiration
of the 60-day period referred to in paragraph  (4) or the date of such
final judgment, as the case may be) in an action brought in any ap-
propriate district court of the United States. In such an action, the
validity, amount, and appropriateness of such penalty shall not be
subject to review.

                            SEIZURE

    SEC. 304. [334] (a)(l) Any article of food, drug, or cosmetic
that is adulterated or misbranded when introduced into  or while in
interstate commerce or while held for sale (whether or not the first
sale) after  shipment  in interstate commerce,  or which may not,
under the provisions of section 404 or 505, be introduced into inter-
state commerce, shall be liable to be proceeded against while in
interstate commerce, or at any time thereafter, on libel  of informa-
tion and condemned in any district court of the United States or
United States court of a Territory within the jurisdiction of which
the article is found. No libel for condemnation shall be instituted
under this Act, for any alleged misbranding  if there is  pending in
any court a libel for condemnation proceeding under this Act based
upon the same alleged  misbranding, and not more than one such
proceeding shall be instituted if no such  proceeding is so pending,

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Sec. 304	FEDERAL FOOD, DRUB, AND COSMETIC ACT	118

except that such limitations shall  not apply  (A) when such  mis-
branding has  been the basis of a  prior judgment in favor of the
United States, in a criminal, injunction, or libel for condemnation
proceeding under this Act, or (B) when the Secretary has probable
cause to believe from facts found, without hearing, by him or any
officer or employee of the Department that the misbranded article
is dangerous to health, or that the labeling of the misbranded arti-
cle  is fraudulent, or would be in a material respect misleading to
the injury  or  damage of the purchaser or consumer. In  any case
where the number of libel for condemnation proceedings is limited
as above provided the proceeding  pending  or instituted  shall, on
application of the claimant, seasonably made, be removed for trial
to any district agreed upon by stipulation between the parties, or,
in case of failure to so stipulate  within a reasonable  time, the
claimant may  apply to the court of the district in which the seizure
has been made,  and such court (after giving the United  States at-
torney for  such district reasonable notice and opportunity to be
heard) shall by order, unless good cause to the contrary is shown,
specify a district of reasonable proximity to the claimant's principal
place of business to which the case shall be removed for trial.
    (2) The following shall be liable to be proceeded against at any
time on libel of information and condemned in any district court of
the United States or United States court of a Territory within the
jurisdiction of which they are found: (A) Any  drug that is a coun-
terfeit drug,  (B) Any container of  a counterfeit  drug, (C) Any
punch, die, plate, stone, labeling, container, or other thing used or
designed for use in making a counterfeit drug or drugs, and (D)
Any adulterated or misbranded device.
    (3)(A) Except as provided in subparagraph (B), no libel for con-
demnation may be instituted under paragraph (1)  or (2) against
any food which—
        (i) is misbranded under section 403(a)(2) because of its ad-
    vertising,  and
        (ii) is being held for sale to the  ultimate consumer in an
    establishment other than an establishment owned or operated
    by a manufacturer, packer, or distributor of the food.
    (B) A  libel  for condemnation  may be instituted under para-
graph (1) or (2) against  a food described in subparagraph (A) if—
        (i)(I) the food's advertising  which resulted in the food being
    misbranded under  section 403(a)(2)  was  disseminated in the
    establishment in which the food is being held for sale to the
    ultimate consumer,
        (II) such advertising was disseminated by, or under the di-
    rection of, the owner or operator of such establishment, or
        (III) all or part of the cost  of such advertising was paid by
    such owner or operator; and
        (ii) the owner or operator of such establishment used such
    advertising  in the  establishment to promote the sale of the
    food.
    (b)  The article, equipment, or other thing proceeded against
shall be liable to seizure by process pursuant to the libel, and the
procedure in  cases under this section shall conform, as  nearly as
may be, to the procedure in admiralty; except that on demand of
either party any issue of fact joined in any such case shall be tried

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V[9	FEDERAL FOOD, DRUG. AND COSMETIC ACT	Sec. 304

by jury. When libel for condemnation proceedings under this sec-
tion, involving the same claimant and the same issues of adultera-
tion or misbranding, are pending in two or more jurisdictions, such
pending proceedings, upon application of the claimant seasonably
made to the court of one such jurisdiction, shall be consolidated for
trial by order of such court, and tried in (1) any  district  selected
by the claimant where one of such  proceedings is pending; or (2)
a district agreed upon  by stipulation between the parties.  If no
order for  consolidation is so made within a reasonable time, the
claimant may apply to the court of one such jurisdiction, and such
court (after giving the United States attorney for such district rea-
sonable notice and  opportunity to be heard) shall by order, unless
good cause to  the contrary is shown,  specify a district of reasonable
proximity to the claimant's principal place of business, in which all
such pending  proceedings shall  be consolidated for trial and tried.
Such order of consolidation shall not apply so as to require the re-
moval of any  case the date for  trial of which has been fixed. The
court granting such order shall  give prompt notification thereof to
the other courts having jurisdiction of the cases covered thereby.
    (c) The court at any time after seizure up to a reasonable time
before trial shall by order allow any party to a condemnation pro-
ceeding, his attorney or agent, to obtain a representative sample of
the article seized and a true copy of the analysis, if any, on which
the proceeding is based and the identifying marks or numbers, if
any, of the packages from  which the samples analyzed were ob-
tained.
    (d)(l) Any food, drug,  device, or cosmetic condemned under this
section shall,  after entry  of the decree, be disposed of by  destruc-
tion or sale as the court may, in accordance with the provisions of
this section, direct  and the  proceeds thereof, if sold, less the legal
costs and charges,  shall be paid into the  Treasury of the United
States; but  such article shall not be  sold  under  such  decree con-
trary to the provisions of this Act or the laws of the jurisdiction in
which sold. After entry of the decree and upon the payment of the
costs of such proceedings and the execution of a good and sufficient
bond conditioned that such  article shall  not be sold or disposed of
contrary to the provisions of this Act or the laws of any  State or
Territory in which sold, the  court may by order direct that such ar-
ticle be delivered to the owner  thereof to be destroyed or brought
into compliance with the provisions of this Act under the super-
vision of an officer or employee duly designated by the Secretary,
and the expenses of such supervision shall be paid by the person
obtaining release of the article  under bond. If the article  was im-
ported into the United States and the person seeking its release es-
tablishes  (A)  that the adulteration, misbranding,  or violation did
not occur after the article was  imported, and (B) that he had no
cause for believing that it was adulterated, misbranded, or in viola-
tion before it was  released from customs  custody, the court may
permit the article to be delivered to the owner for exportation in
lieu of destruction upon a showing by the owner that all of the con-
ditions of section 801(e) can and will be met. The provisions of this
sentence shall not apply where  condemnation is based upon viola-
tion of section 402(a) (1), (2), or  (6), section 501(a)(3), section 502(j),
or section 601 (a) or (d). Where such exportation is made to the

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Sec. 304	FEDERAL FOOD. DRUB, AND COSMETIC ACT	120

original foreign supplier, then paragraphs (1)  and (2) of section
801(e) and the preceding sentence shall not be applicable; and in
all cases of exportation the bond shall be conditioned that the arti-
cle shall not be sold or disposed  of until the applicable conditions
of section  801(e) have been met. Any article condemned by reason
of its being an article which may not, under section 404 or 505, be
introduced into interstate commerce, shall be disposed of by de-
struction.
    (2) The  provisions of paragraph (1) of this subsection  shall, to
the extent deemed appropriate by the  court, apply to any equip-
ment or other thing which is not otherwise within the scope of such
paragraph and which is  referred  to in paragraph (2) of subsection
(a).
    (3) Whenever  in any proceeding under this section, involving
paragraph (2) of subsection (a), the condemnation of any equipment
or thing (other than a drug) is decreed, the court shall allow the
claim of any claimant, to the extent of such claimant's interest, for
remission  or mitigation of such forfeiture  if such claimant proves
to the  satisfaction of the court (i) that he has  not committed or
caused to  be committed any prohibited act referred to in such para-
graph (2)  and has no interest in any drug referred to  therein, (ii)
that he  has  an interest in such equipment or other thing as owner
or lienor or otherwise, acquired by him  in good faith, and (iii) that
he at no  time had any knowledge or reason to believe that such
equipment or other thing was being or  would be used in, or to fa-
cilitate, the violation of laws of the United States relating  to coun-
terfeit drugs.
    (e) When a decree of condemnation  is entered against the arti-
cle, court  costs and fees, and storage and  other proper expenses,
shall be awarded against the person, if any, intervening as claim-
ant of the  article.
    (f)  In  the case of removal for trial  of any case as provided by
subsection (a) or (b)—
        (1) The clerk of the court from which removal  is made
    shall  promptly transmit to the court in which the case is to be
    tried  all records in the case necessary  in order that such court
    may exercise jurisdiction.
        (2) The court to which such case was removed shall have
    the powers and be subject to the duties for purposes of such
    case,  which the court from  which removal was made would
    have  had, or to which such court would have been subject, if
    such case had  not been removed.
    (g)(l)  If during an inspection conducted under section  704 of a
facility or  a vehicle, a device which the  officer or employee making
the inspection has reason to believe is  adulterated  or  misbranded
is found in  such facility or vehicle, such officer or employee may
order the device  detained (in accordance with regulations  pre-
scribed by the Secretary) for a reasonable period which may not ex-
ceed twenty days unless the Secretary determines that a period of
detention  greater than twenty days is required to institute an ac-
tion  under subsection (a) or section 302, in which case  he  may au-
thorize a  detention period of not to exceed thirty days. Regulations
of the Secretary prescribed under this paragraph shall require  that
before a device may be ordered detained under  this paragraph the

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121	FEDERAL FOOD. DRUG, AND COSMETIC ACT	Sec. 306

Secretary or an officer or employee designated by the Secretary ap-
prove such order. A detention order under this paragraph may re-
quire the labeling or  marking of a device during the period of its
detention for the purpose of identifying the device as detained. Any
person who would  be entitled to claim a device if it  were seized
under subsection (a)  may  appeal to the Secretary a detention of
such device under this paragraph. Within five days of the date an
appeal of a  detention is  filed with  the Secretary,  the Secretary
shall  after affording opportunity for an informal hearing by order
confirm the detention or revoke it.
    (2)(A) Except as authorized by subparagraph (B), a device sub-
ject to a detention order issued under paragraph (1) shall  not be
moved by any person  from the place at which it is ordered detained
until—
        (i) released by the Secretary, or
        (ii) the  expiration  of the  detention  period applicable to
    such order,
whichever occurs first.
    (B) A device subject to a detention order under paragraph (1)
may be moved—
        (i) in accordance  with regulations prescribed  by the Sec-
    retary, and
        (ii) if not  in  final  form for  shipment, at the discretion of
    the manufacturer of the device for the purpose of completing
    the work required to put it in such form.

         HEARING BEFORE REPORT OF CRIMINAL VIOLATION

    SEC. 305. [335] Before any violation of this Act is reported by
the Secretary to any United States attorney for institution of  a
criminal proceeding, the person against whom such proceeding is
contemplated shall be given appropriate notice and an opportunity
to present his views, either orally or in writing, with regard to such
contemplated proceeding.

   DEBARMENT, TEMPORARY DENIAL OF APPROVAL, AND SUSPENSION

    SEC. 306. [335al  (a) MANDATORY DEBARMENT.—
        (1) CORPORATIONS, PARTNERSHIPS, AND  ASSOCIATIONS.—If
    the Secretary finds that a person other than an individual has
    been convicted, after the date of the enactment of this section,
    of a felony under  Federal law for conduct relating to the devel-
    opment or approval, including  the process for development or
    approval, of any  abbreviated  drug application,  the Secretary
    shall  debar  such  person from  submitting, or assisting in the
    submission of, any such application.
        (2) INDIVIDUALS.—If the Secretary finds that an individual
    has been convicted of a felony under Federal law for conduct—
            (A) relating to the development or approval, including
        the process for development or approval, of any drug prod-
        uct, or
            (B)  otherwise  relating to the regulation of any  drug
        product under this Act,

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Sec. 306	FEDERAL FOOD, DRUG, AND  COSMETIC ACT	122

    the Secretary shall debar such individual from  providing serv-
    ices in any capacity to a person that has an approved or pend-
    ing drug product application.
    (b) PERMISSIVE DEBARMENT.—
        (1)  IN  GENERAL.—The  Secretary, on the Secretary's  own
    initiative or in response to  a  petition, may, in accordance with
    paragraph (2), debar—
            (A) a person other  than an individual from submitting
        or assisting in the submission  of any abbreviated drug ap-
        plication, or
            (B) an individual from providing services in any capac-
        ity to a person that has an approved or pending drug prod-
        uct application.
        (2) PERSONS SUBJECT TO PERMISSIVE DEBARMENT.—The fol-
    lowing persons are subject  to debarment under paragraph (1):
            (A)  CORPORATIONS,   PARTNERSHIPS,   AND   ASSOCIA-
        TIONS.—Any person other than an individual that the Sec-
        retary finds has been convicted—
                (i) for conduct that—
                    (I) relates  to the development or approval, in-
                cluding  the process for  the development  or  ap-
                proval, of any abbreviated drug application; and
                    (II) is a felony under Federal law (if the per-
                son  was  convicted before the date of the enact-
                ment of this section),  a misdemeanor under Fed-
                eral law, or a felony under State law, or
                (ii) of a conspiracy to commit, or  aiding or abet-
            ting, a criminal offense described in clause (i) or a fel-
            ony described in subsection (a)(l),
        if  the  Secretary finds that  the type  of  conduct which
        served  as the basis for  such  conviction undermines  the
        process for the regulation of drugs.
            (B) INDIVIDUALS.—
                (i) Any individual whom the Secretary finds has
            been convicted of—
                    (I) a misdemeanor under Federal law or a fel-
                ony under State  law  for conduct relating  to the
                development or approval, including the process for
                development or approval, of any drug product or
                otherwise relating to the regulation of drug prod-
                ucts under this Act, or
                    (II) a conspiracy to commit, or aiding or abet-
                ting, such criminal offense or a felony described in
                subsection (a)(2),
            if the Secretary finds that the  type of conduct which
            served as the basis for such conviction undermines the
            process for the regulation of drugs.
                (ii) Any individual whom the Secretary finds has
            been convicted of—
                    (I)  a felony  which  is  not described  in  sub-
                section (a)(2)   or clause (i)  of this subparagraph
                and which  involves bribery,  payment of illegal
                gratuities, fraud, perjury,  false statement, rack-
                eteering, blackmail, extortion, falsification or de-

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123	FEDERAL FOOD, DRUB. AND COSMETIC ACT	Sec. 306

                struction of records, or interference with, obstruc-
                tion of an investigation into, or prosecution of, any
                criminal offense, or
                    (II) a conspiracy to commit, or aiding or abet-
                ting, such felony,
            if the Secretary finds, on the basis of the conviction of
            such individual and other information, that such indi-
            vidual has demonstrated a pattern of conduct suffi-
            cient to find that there  is reason to believe that such
            individual may violate requirements under this Act re-
            lating to drug products.
                (iii) Any individual whom the Secretary finds ma-
            terially participated  in acts that were the basis for a
            conviction for an offense described in subsection (a) or
            in clause (i) or (ii) for which a conviction was obtained,
            if the Secretary finds, on the basis of such participa-
            tion and other information, that such individual has
            demonstrated a pattern of conduct  sufficient to find
            that there is reason to  believe that such  individual
            may violate requirements  under this Act relating to
            drug products.
                (iv) Any high managerial agent whom the  Sec-
            retary finds—
                    (I) worked for, or worked as a consultant for,
                the same person as another individual during the
                period in which such other individual took actions
                for which a felony conviction was obtained and
                which resulted in the debarment under subsection
                (a)(2), or clause (i), of such other individual,
                    (II)  had actual knowledge of the actions de-
                scribed in subclause (I) of such other individual, or
                took action to  avoid such  actual knowledge,  or
                failed to take action  for the purpose of avoiding
                such actual knowledge,
                    (III)  knew that the actions  described in sub-
                clause (I) were violative of law, and
                    (IV)  did not report  such actions, or  did  not
                cause such actions  to be reported, to  an officer,
                employee, or agent of the Department or to an ap-
                propriate law enforcement officer, or failed to take
                other appropriate action  that would have  ensured
                that the process for the regulation of drugs was
                not undermined, within a reasonable time after
                such agent first knew of such actions,
            if the Secretary finds that the type of conduct which
            served as the basis for such  other individual's convic-
            tion undermines  the process  for the regulation of
            drugs.
        (3)  STAY OF CERTAIN  ORDERS.—An order of the Secretary
    under clause (iii) or  (iv) of paragraph (2)(B) shall not take ef-
    fect until 30 days after the order has been issued.
    (c) DEBARMENT PERIOD AND CONSIDERATIONS.—
        (1) EFFECT OF DEBARMENT.—The Secretary—

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Sec. 306	FEDERAL FOOD, DRUB, AND  COSMETIC ACT	124

            (A) shall not accept  or review (other than in connec-
        tion  with an audit under this section) any  abbreviated
        drug application submitted by or with the  assistance of a
        person debarred under subsection (a)(l) or (b)(2)(A) during
        the period such person is debarred,
            (B) shall, during the  period of a debarment under sub-
        section (a)(2) or (b)(2)(B), debar an individual from provid-
        ing services in  any capacity to a person that has an ap-
        proved or pending drug product application and shall not
        accept or review (other than in connection with an  audit
        under this section) an abbreviated drug application from
        such individual, and
            (C) shall, if the Secretary makes the finding described
        in paragraph (6) or (7) of section 307(a), assess a civil pen-
        alty in accordance with section 307.
        (2) DEBARMENT PERIODS.—
            (A) IN GENERAL.—The Secretary shall debar a person
        under subsection (a) or (b) for the following periods:
               (i) The  period of debarment  of a  person (other
            than an individual) under subsection (a)(l) shall not
            be less than 1 year or more than 10 years, but if an
            act leading  to a  subsequent  debarment  under  sub-
            section (a)  occurs within  10  years after such person
            has been debarred under subsection (a)(l), the period
            of debarment shall be permanent.
               (ii) The debarment of an individual  under  sub-
            section (a)(2) shall be permanent.
               (iii) The period of debarment of any person under
            subsection (b)(2) shall not be more than 5 years.
        The Secretary may determine whether debarment periods
        shall run concurrently or consecutively in  the case  of a
        person debarred for multiple offenses.
            (B) NOTIFICATION.—Upon  a conviction for an offense
        described in subsection (a) or  (b) or upon execution  of an
        agreement with the United States to plead  guilty to  such
        an offense, the person involved may  notify the Secretary
        that the person acquiesces to debarment and such person's
        debarment shall commence upon such notification.
        (3) CONSIDERATIONS.—In determining the appropriateness
    and the period of a debarment of a person under subsection (b)
    and any period of debarment beyond the minimum specified in
    subparagraph (A)(i) of paragraph (2), the Secretary shall con-
    sider where applicable—
            (A) the nature and seriousness of any offense involved,
            (B) the  nature and extent of management participa-
        tion  in any offense involved, whether corporate  policies
        and practices encouraged the offense,  including whether
        inadequate institutional  controls  contributed  to  the of-
        fense,
            (C) the nature and extent of voluntary steps to miti-
        gate the impact on the public of any offense involved, in-
        cluding the recall or the discontinuation of the distribution
        of suspect drugs, full  cooperation with any investigations
        (including the extent of disclosure to  appropriate authori-

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125	FEDERAL FOOD, DRUE, AND COSMETIC ACT	Sec. 306

        ties of all wrongdoing), the relinquishing of profits on drug
        approvals  fraudulently obtained, and  any other  actions
        taken to substantially limit potential or actual adverse ef-
        fects on the public health,
            (D) whether the extent to which changes in ownership,
        management, or operations  have corrected the causes of
        any offense  involved  and provide reasonable assurances
        that the offense will not occur in the future,
            (E) whether the  person to be  debarred is  able  to
        present adequate  evidence  that  current production  of
        drugs  subject to  abbreviated  drug  applications  and all
        pending abbreviated drug applications are free of fraud or
        material false statements, and
            (F) prior convictions under  this Act  or  under other
        Acts involving matters within the jurisdiction of the Food
        and Drug Administration.
    (d) TERMINATION OF DEBARMENT.—
        (1) APPLICATION.—Any person that is debarred under sub-
    section (a)  (other than a person permanently debarred) or any
    person that is  debarred  under subsection (b) may apply to the
    Secretary for  termination of the debarment under this sub-
    section. Any information submitted to the Secretary under this
    paragraph does not constitute an amendment or supplement to
    pending or  approved abbreviated drug applications.
        (2) DEADLINE.—The Secretary shall grant  or deny any ap-
    plication respecting a  debarment  which is submitted under
    paragraph  (1)  within  180 days of  the  date the application is
    submitted.
        (3) ACTION BY THE SECRETARY.—
            (A) CORPORATIONS.—
                (i) CONVICTION REVERSAL.—If the conviction which
            served as the basis  for the debarment  of a person
            under subsection (a)(l)  or (b)(2)(A)  is reversed, the
            Secretary shall withdraw the order of debarment.
                (ii)  APPLICATION.—Upon  application  submitted
            under paragraph (1), the Secretary shall terminate the
            debarment of a person if the Secretary finds that—
                    (I) changes in ownership, management, or op-
                erations have fully corrected the causes of the of-
                fense involved and provide reasonable assurances
                that the offense will not occur in the future, and
                    (II) sufficient audits, conducted  by the Food
                and Drug Administration or by independent ex-
                perts acceptable  to  the Food and Drug Adminis-
                tration,  demonstrate  that pending  applications
                and the development of drugs being  tested before
                the  submission of an application are  free  of fraud
                or material false statements.
            In  the  case  of persons debarred  under subsection
            (a)(l), such termination shall take effect no earlier
            than the expiration of one year from the date of the
            debarment.
            (B) INDIVIDUALS.—

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Sec. 306	FEDERAL FOOD, DRUB, AND COSMETIC ACT	126

                (i) CONVICTION REVERSAL.—If the conviction which
            served as the basis for the debarment of an individual
            under subsection (a)(2) or clause (i), (ii), (iii), or (iv) of
            subsection (b)(2)(B)  is reversed,  the  Secretary shall
            withdraw the order of debarment.
                (ii)  APPLICATION.—Upon  application  submitted
            under paragraph (1), the  Secretary shall terminate the
            debarment  of an individual who  has been debarred
            under subsection (b)(2)(B) if such termination serves
            the interests of justice and adequately protects the in-
            tegrity of the drug approval process.
        (4) SPECIAL TERMINATION.—
            (A) APPLICATION.—Any person that is debarred under
        subsection  (a)(l)  (other  than a  person  permanently
        debarred under subsection (c)(2)(A)(i)) or  any individual
        who is debarred under subsection  (a)(2) may apply to the
        Secretary for special termination of debarment under this
        subsection. Any information  submitted to  the  Secretary
        under  this subparagraph does not constitute an  amend-
        ment  or supplement to pending or approved abbreviated
        drug applications.
            (B) CORPORATIONS.—Upon an application submitted
        under  subparagraph (A), the Secretary may take the ac-
        tion described in  subparagraph (D) if the Secretary, after
        an informal hearing, finds that—
                (i) the person making the application under sub-
            paragraph (A) has demonstrated that the felony con-
            viction which  was the basis for such person's debar-
            ment involved the commission  of an offense which was
            not authorized, requested, commanded, performed, or
            recklessly tolerated by the board of directors  or by a
            high managerial agent acting  on behalf of the person
            within the scope of the board's or agent's office or em-
            ployment,
                (ii) all individuals who were involved in the com-
            mission of the offense or who knew or should have
            known of the offense have been removed from  employ-
            ment involving the  development  or approval of any
            drug subject to section 505 or 507,
                (iii) the person fully  cooperated with all investiga-
            tions and promptly disclosed all wrongdoing to the ap-
            propriate authorities, and
                (iv) the person acted  to mitigate any impact on the
            public of any offense involved, including the recall, or
            the discontinuation  of the distribution, of any drug
            with respect to which the Secretary requested a recall
            or  discontinuation  of distribution due to  concerns
            about the safety or efficacy of the drug.
            (C)  INDIVIDUALS.—Upon an  application  submitted
        under  subparagraph (A), the Secretary may take the ac-
        tion described in  subparagraph (D) if the Secretary, after
        an  informal hearing, finds that such individual has pro-
        vided substantial assistance  in the investigations  or pros-
        ecutions of offenses which are described in subsection  (a)

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127	FEDERAL FOOD,  DRUB, AND COSMETIC ACT	Sec. 306

        or (b) or which relate to any matter under the jurisdiction
        of the Food and Drug Administration.
            (D) SECRETARIAL ACTION.—The action referred  to  in
        subparagraphs (B) and (C) is—
                (i) in the case of a person other than an individ-
            ual—
                    (I) terminating the debarment immediately, or
                    (II)  limiting the period of debarment to less
                than one year, and
                (ii) in the case of an individual, limiting the period
            of debarment  to less  than permanent but to no less
            than 1 year,
        whichever best serves the  interest of justice and protects
        the integrity of the drug approval process.
    (e) PUBLICATION AND LIST OF DEBARRED  PERSONS.—The Sec-
retary shall publish in the Federal Register the name of any person
debarred under subsection (a) or (b), the effective date of the debar-
ment, and the period of the debarment. The  Secretary shall also
maintain and make  available to the public a list, updated no less
often than quarterly, of such persons, of the  effective dates and
minimum periods  of such  debarments, and of the termination of
debarments.
    (f) TEMPORARY DENIAL OF APPROVAL.—
        (1)  IN GENERAL.—The Secretary, on the Secretary's own
    initiative or in response to a petition, may, in accordance with
    paragraph (3), refuse  by order, for the  period  prescribed  by
    paragraph (2), to  approve any abbreviated drug application
    submitted by any person—
            (A) if such person is under an active Federal criminal
        investigation in connection with an  action  described  in
        subparagraph (B),
            (B) if the Secretary finds that such person—
                (i) has bribed or attempted to bribe, has paid or
            attempted to pay an illegal gratuity, or has induced or
            attempted to induce another person to bribe or pay  an
            illegal gratuity to any officer, employee, or agent of the
            Department of Health  and Human Services  or to any
            other Federal, State, or local official in connection with
            any abbreviated  drug application, or has conspired to
            commit, or aided or abetted, such actions, or
                (ii) has  knowingly made or caused  to be made a
            pattern  or practice of false statements or misrepresen-
            tations with respect to material facts relating to any
            abbreviated  drug application, or the production of any
            drug subject to an abbreviated drug application, to any
            officer,  employee, or  agent of the  Department  of
            Health and Human Services, or has conspired to com-
            mit, or aided or abetted, such actions, and
            (C) if a significant question has  been raised regard-
        ing—
               (i) the integrity of the approval process  with re-
            spect to such abbreviated drug application, or
               (ii)  the  reliability  of data in or concerning such
            person's abbreviated drug application.

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Sec. 306	FEDERAL FOOD, DRU6, AND  COSMETIC  ACT	128

    Such an order may be modified or terminated at any time.
        (2) APPLICABLE PERIOD.—
            (A) IN GENERAL.—Except as provided in subparagraph
        (B), a denial of approval of an  application of a person
        under paragraph  (1)  shall be in effect  for a period deter-
        mined by the Secretary but not to exceed 18 months begin-
        ning on the date the Secretary finds that the conditions
        described in subparagraphs (A), (B), and (C) of paragraph
        (1) exist. The Secretary shall terminate  such denial—
               (i)  if the  investigation with respect to which the
            finding was made does not result in a criminal charge
            against  such  person, if criminal charges have been
            brought and the  charges have been dismissed, or if a
           judgment of acquittal has been entered, or
               (ii) if the Secretary  determines that such finding
            was in error.
            (B) EXTENSION.—If, at the end of the period described
        in subparagraph (A), the Secretary determines that a per-
        son has been criminally charged for an action described in
        subparagraph (B) of paragraph (1), the Secretary may ex-
        tend the period of denial of approval of an application for
        a period not to exceed 18 months. The Secretary shall ter-
        minate such extension if the charges have been dismissed,
        if a judgment of acquittal has  been entered, or if the  Sec-
        retary determines that  the finding described in subpara-
        graph (A) was in error.
        (3) INFORMAL HEARING.—Within  10 days of the date an
    order is issued  under paragraph (1),  the Secretary shall  pro-
    vide such person with an opportunity for an informal hearing,
    to be held within such 10 days, on the decision of the Secretary
    to refuse approval  of an  abbreviated drug application. Within
    60 days of the  date on which such hearing is held,  the  Sec-
    retary shall notify the person given such hearing whether the
    Secretary's refusal of approval will be continued, terminated,
    or otherwise modified. Such notification shall be final agency
    action.
    (g) SUSPENSION  AUTHORITY.—
        (1) IN GENERAL.—If—
            (A) the  Secretary finds—
               (i) that a  person has engaged in conduct described
           in subparagraph (B) of subsection  (f)(l) in  connection
            with 2  or more drugs under abbreviated drug applica-
            tions, or
               (ii) that a person has  engaged  in flagrant and re-
            peated,  material violations  of  good  manufacturing
            practice or good laboratory practice in connection with
            the development, manufacturing, or distribution of one
            or more drugs approved under an abbreviated drug
            application during a 2-year period, and—
                    (I)  such  violations may undermine the safety
               and efficacy of such drugs, and
                    (II) the  causes  of such violations  have not
               been corrected within  a reasonable period of time

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 129	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 306

                following  notice of  such violations by  the Sec-
                retary, and
            (B) such person is under an active investigation by a
        Federal authority in connection with a civil or criminal ac-
        tion involving conduct described in subparagraph (A),
    the Secretary shall issue an order suspending the distribution
    of all drugs the development or approval of which was related
    to such conduct described in subparagraph (A) or  suspending
    the distribution of all drugs approved under abbreviated drug
    applications of such person if the Secretary finds that such
    conduct may have affected  the  development or approval of a
    significant number of drugs which the Secretary is unable to
    identify. The Secretary shall exclude a drug from such order if
    the Secretary determines that  such conduct was not likely to
    have influenced the safety or efficacy of such drug.
        (2) PUBLIC HEALTH WAIVER.—The Secretary shall, on the
    Secretary's  own initiative or in response to a petition, waive
    the suspension under  paragraph  (1) (involving an action de-
    scribed in paragraph (l)(A)(i)) with respect to  any  drug if the
    Secretary finds  that such waiver is  necessary to protect the
    public health  because  sufficient quantities of the drug would
    not otherwise be available. The Secretary shall act on any peti-
    tion seeking action under this paragraph  within 180 days of
    the date the petition is submitted to the Secretary.
    (h) TERMINATION OF SUSPENSION.—The Secretary  shall with-
 draw an order  of suspension of the  distribution of a drug under
 subsection (g) if the person with respect to whom the order was is-
 sued demonstrates in a petition to the Secretary—
        (1)(A) on the basis of an audit by the Food and Drug Ad-
    ministration or by experts acceptable to the Food and Drug Ad-
    ministration, or on the basis of other information, that the de-
    velopment,  approval, manufacturing,  and distribution of such
    drug is in substantial compliance with the applicable require-
    ments of this Act, and
        (B) changes in ownership, management, or operations—
            (i) fully remedy the patterns  or practices with respect
        to which the order was issued, and
            (ii)  provide reasonable  assurances  that such  actions
        will not occur in the future, or
        (2) the initial determination was in error.
The Secretary shall act on  a submission of a  petition  under this
subsection within  180 days of the date of its submission  and the
Secretary may consider the petition concurrently with the suspen-
sion proceeding. Any information submitted to the Secretary under
this subsection does not constitute an amendment or supplement to
a pending or approved abbreviated drug application.
    (i) PROCEDURE.—The Secretary may not take any action under
subsection (a), (b), (c), (d)(3), (g), or (h) with respect to any person
unless the Secretary has issued an order for such action  made on
the record after opportunity for  an agency hearing on disputed is-
sues of material fact. In the course of any investigation or hearing
under this subsection, the Secretary may  administer oaths and af-
firmations, examine witnesses, receive evidence, and issue subpoe-
nas requiring  the attendance and testimony of witnesses and the

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Sec. 306	FEDERAL  FOOD, DRUB, AND COSMETIC ACT	130

production of evidence that relates to the matter under investiga-
tion.
    (j) JUDICIAL REVIEW.—
        (1) IN GENERAL.—Except as provided in paragraph (2), any
    person that is the  subject of an adverse decision under sub-
    section (a), (b), (c), (d), (f), (g), or (h) may  obtain a  review of
    such decision by the United States Court  of Appeals for the
    District of Columbia or for the circuit in which the person re-
    sides, by filing in such court (within 60 days following the date
    the person is notified of the Secretary's decision) a petition re-
    questing that the decision be modified or set aside.
        (2) EXCEPTION.—Any person that is the subject  of an  ad-
    verse decision under clause (iii)  or  (iv)  of subsection (b)(2)(B)
    may obtain a review of such decision by the United States Dis-
    trict Court for the District of Columbia or a district court of the
    United States for the district in which the person resides, by
    filing in such court (within 30 days following the  date the per-
    son is notified of the Secretary's decision) a complaint request-
    ing that  the  decision be modified or set aside. In such an  ac-
    tion, the  court shall determine the matter de novo.
    (k)  CERTIFICATION.—Any application  for approval of a drug
product shall include—
        (1) a certification that the applicant did not and will  not
    use in any capacity the services of any person debarred under
    subsection (a) or (b), in connection with such application, and
        (2) if such application is an  abbreviated drug application,
    a list of all  convictions,  described in subsections (a) and (b)
    which  occurred within the previous 5 years, of the applicant
    and affiliated persons responsible for the development or sub-
    mission of such application.
    (1) APPLICABILITY.—
        (1) CONVICTION.—For purposes of this section, a person is
    considered to have been convicted of a criminal offense—
            (A) when a judgment of conviction has been entered
        against the person by a Federal or State court, regardless
        of whether there is an appeal pending,
            (B) when a plea of guilty or nolo contendere by  the
        person has been accepted by a Federal or State  court, or
            (C) when the person has entered into participation in
        a first offender, deferred adjudication, or other similar ar-
        rangement or program where judgment  of conviction has
        been withheld.
        (2) EFFECTIVE DATES.—Subsection (a), subparagraph (A) of
    subsection (b)(2), and clauses (i)  and (ii) of subsection (b)(2)(B)
    shall not apply to a conviction  which occurred  more than  5
    years before the  initiation of an agency action proposed to be
    taken under subsection (a) or (b). Clauses (iii) and (iv) of sub-
    section (b)(2)(B) and subsections (f) and (g) shall not apply to
    an act or action  which occurred  more than 5 years before  the
    initiation of an agency action proposed to be taken under sub-
    section (b), (f), or (g). Clause (iv) of subsection  (b)(2)(B) shall
    not apply  to  an action  which occurred before June 1,  1992.
    Subsection (k) shall not  apply to applications submitted to  the
    Secretary before June 1, 1992.

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131	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 307

                        CIVIL PENALTIES

    SEC. 307. [335b] (a) IN GENERAL.—Any person that the Sec-
retary finds—
        (1) knowingly made or caused to be made, to any officer,
    employee, or agent of the Department of Health and Human
    Services, a false statement or misrepresentation of a material
    fact in connection with an abbreviated drug application,
        (2) bribed or attempted to bribe  or  paid or attempted to
    pay an illegal gratuity to any officer, employee, or agent of the
    Department of Health and Human Services in connection with
    an abbreviated drug  application,
        (3) destroyed, altered,  removed, or  secreted, or  procured
    the destruction, alteration,  removal, or secretion of, any mate-
    rial document or  other material evidence which was the prop-
    erty of or in the  possession of the Department of Health and
    Human Services  for the purpose of interfering with  that De-
    partment's discharge of its responsibilities in connection with
    an abbreviated drug  application,
        (4) knowingly failed to disclose, to an officer or employee
    of the Department of Health and Human Services, a material
    fact which such person had an obligation to disclose relating to
    any drug subject to an abbreviated drug application,
        (5) knowingly obstructed an investigation  of the Depart-
    ment of Health and  Human Services  into any drug subject to
    an abbreviated drug  application,
        (6) is  a person that  has an approved or pending drug prod-
    uct application and has knowingly—
            (A) employed or retained as a consultant or contractor,
        or
            (B) otherwise used in any capacity the services of,
    a person who was debarred under section 306, or
        (7) is  an individual debarred under section 306 and, during
    the period of debarment, provided services in any capacity to
    a person that had an approved or pending drug product appli-
    cation,
shall be liable to the United States for a civil penalty for each such
violation in an amount not to exceed $250,000 in the case of an in-
dividual and $1,000,000 in the case of any other person.
    (b) PROCEDURE.—
        (1) IN GENERAL.—
            (A) ACTION BY THE SECRETARY.—A civil penalty under
        subsection (a) shall  be assessed by the Secretary on a per-
        son by an order made  on the record after an  opportunity
        for an agency hearing on disputed issues of material fact
        and the amount  of the penalty. In the course of any inves-
        tigation or hearing under this subparagraph, the Secretary
        may   administer oaths  and affirmations, examine  wit-
        nesses, receive evidence,  and issue subpoenas requiring
        the attendance and  testimony of witnesses and the produc-
        tion of evidence that relates to the matter under investiga-
        tion.
           (B) ACTION BY  THE ATTORNEY GENERAL.—In lieu of a
        proceeding under subparagraph (A),  the Attorney General

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Sec. 308	FEDERAL FOOD, DRUB, AND COSMETIC ACT	132

        may, upon request of the Secretary, institute a civil action
        to recover a civil money penalty in the amount and for any
        of the acts set forth in subsection (a). Such an action may
        be instituted separately from or in connection with any
        other claim,  civil  or  criminal, initiated by the Attorney
        General under this Act.
        (2) AMOUNT.—In determining the amount of a civil penalty
    under paragraph  (1), the Secretary or the court shall take into
    account the nature, circumstances, extent, and gravity of the
    act subject to penalty, the person's ability to pay, the effect on
    the person's ability to  continue to do business, any history of
    prior, similar acts, and such other matters  as justice may re-
    quire.
        (3) LIMITATION ON  ACTIONS.—No action may be initiated
    under this section—
            (A) with  respect to any act described in subsection (a)
        that occurred before the date of the enactment of this sec-
        tion, or
            (B) more than 6 years after the date when facts mate-
        rial to the act are known or  reasonably should have been
        known by the Secretary but in  no event more than 10
        years after the date the act took place.
    (c) JUDICIAL REVIEW.—Any person that is the subject of an ad-
verse decision under  subsection (b)(l)(A) may obtain a review  of
such decision by the United States Court of Appeals for the  District
of Columbia or for the circuit in which the person resides, by filing
in such court (within  60 days following the date the person is noti-
fied of the Secretary's decision) a petition requesting that the deci-
sion be modified or set aside.
    (d)  RECOVERY OF PENALTIES.—The Attorney General may re-
cover any civil penalty (plus interest at the currently prevailing
rates from the  date the penalty became final) assessed under sub-
section  (b)(l)(A) in an action brought in  the name  of the United
States.  The amount of such penalty  may be deducted, when the
penalty has become final, from any sums then or later owing by the
United States to the person against whom the penalty has been as-
sessed.  In an action  brought under  this subsection, the validity,
amount, and appropriateness of the penalty shall not be subject to
judicial review.
    (e) INFORMANTS.—The  Secretary may award to any individual
(other than an officer or employee of  the Federal Government or a
person  who materially participated in any conduct described  in
subsection (a))  who provides information leading to the imposition
of a civil penalty under this section an amount not to exceed—
        (1) $250,000,  or
        (2) one-half of the penalty so imposed and collected,
whichever is less. The decision of the Secretary on  such award
shall not be reviewable.

    AUTHORITY TO WITHDRAW APPROVAL OF ABBREVIATED DRUG
                         APPLICATIONS

    SEC. 308. [335c] (a) IN GENERAL.—The Secretary—
        (1) shall withdraw  approval of an abbreviated drug appli-
    cation if the Secretary finds that the approval was obtained,

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133	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 310

    expedited, or otherwise facilitated through bribery, payment of
    an illegal gratuity, or fraud or material false statement, and
        (2) may withdraw approval of an abbreviated drug applica-
    tion if the Secretary finds that  the applicant has repeatedly
    demonstrated a lack of ability to produce the drug for which
    the application was submitted in accordance with the formula-
    tions or manufacturing practice  set forth in the abbreviated
    drug application and has introduced, or  attempted to intro-
    duce, such adulterated or misbranded drug into commerce.
    (b) PROCEDURE.—The Secretary may not take any action under
subsection (a) with respect to any person unless the Secretary has
issued an order for such action  made on the record after oppor-
tunity for an agency hearing on disputed issues of material fact. In
the course of any investigation or hearing under this subsection,
the Secretary may administer oaths and affirmations, examine wit-
nesses, receive evidence, and issue subpoenas requiring the attend-
ance  and testimony of witnesses and the production of evidence
that relates to the matter under investigation.
    (c) APPLICABILITY.—Subsection (a) shall  apply with respect  to
offenses  or acts  regardless of when such offenses or acts occurred.
    (d) JUDICIAL REVIEW.—Any person that is the subject of an ad-
verse decision under subsection (a) may obtain a review of such de-
cision by the United States  Court of Appeals for the District of Co-
lumbia or for the circuit in which the person  resides, by filing in
such court (within 60 days following the date the person is notified
of the Secretary's decision)  a petition requesting that the decision
be modified  or set aside.

                  REPORT OF MINOR VIOLATIONS

    SEC. 309. [336] Nothing in this  Act shall be construed as re-
quiring the  Secretary to report for prosecution, or for the institu-
tion of libel or injunction proceedings, minor violations of this Act
whenever he believes that  the public interest will  be adequately
served by a suitable written notice or  warning.

    PROCEEDINGS IN NAME OF UNITED STATES; PROVISION AS TO
                           SUBPOENAS

    SEC. 310. [337]  (a) Except as provided in subsection (b), all
such proceedings for  the  enforcement, or to  restrain violations,  of
this Act shall be by and in the name  of the United States. Subpoe-
nas for witnesses who are required to attend a court of the United
States, in any district, may run into  any other district in any pro-
ceeding under this section.
    (b)(l) A State may bring in its own name and within its juris-
diction proceedings for the  civil enforcement, or to  restrain viola-
tions, of section 401, 403(b), 403(c),  403(d),  403(e),  403(f), 403(g),
403(h), 403(i), 403(k), 403(q), or 403(r) if the food that is the subject
of the proceedings is located in the State.
    (2) No proceeding may  be  commenced by a State under para-
graph (1)—
        (A)  before 30 days after  the  State has given notice to the
    Secretary that the State intends to bring such proceeding,

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Sec. 310	FEDERAL FOOD. DRUG, AND COSMETIC ACT	134

        (B) before 90 days after the State has given notice to the
    Secretary of such  intent if the  Secretary has, within such 30
    days, commenced  an informal  or formal enforcement action
    pertaining to the food which would be the subject of such pro-
    ceeding, or
        (C) if the Secretary is diligently prosecuting a proceeding
    in court pertaining to such food, has settled such proceeding,
    or has settled the informal or formal enforcement action per-
    taining to such food.
In any court  proceeding described  in subparagraph  (C),  a State
may intervene as a matter of right.

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                      CHAPTER IV—FOOD

              DEFINITIONS AND STANDARDS FOR FOOD

    SEC. 401.  [341J Whenever  in the judgment of the Secretary
such  action will promote honesty and fair dealing in the interest
of consumers, he shall promulgate regulations fixing and establish-
ing for any food, under its common or usual name  so far as prac-
ticable, a reasonable definition and standard of identity, a reason-
able  standard of quality, or reasonable  standards of fill of con-
tainer.  No definition and standard  of identity and no standard of
quality shall be established for fresh or dried fruits, fresh or dried
vegetables, or butter, except that definitions and standards of iden-
tity may be established for  avocados, cantaloupes, citrus fruits, and
melons. In prescribing any standard of fill of container,  the Sec-
retary shall give due consideration to the natural shrinkage in stor-
age and in  transit of fresh natural food  and to need for  the nec-
essary packing and protective material.  In the prescribing of any
standard of quality for any canned  fruit or canned  vegetable, con-
sideration shall be given and due allowance made for the  differing
characteristics of the several varieties of such fruit or vegetable. In
prescribing  a definition and  standard of identity for any food or
class  of food in which optional ingredients are permitted,  the Sec-
retary shall, for the purpose of promoting honesty and fair dealing
in the  interest of consumers, designate the optional ingredients
which shall be named on the label.  Any definition and standard of
identity prescribed by the Secretary for avocados, cantaloupes, cit-
rus fruits, or melons shall relate  only to maturity and to the effects
of freezing.

                       ADULTERATED FOOD

    SEC. 402. [342] A food  shall  be deemed to be adulterated—
    (a)1(l) If it bears or contains any poisonous or deleterious sub-
stance which may render it injurious to health; but in case the sub-
stance is not an added substance such food shall not be considered
adulterated under this clause if the quantity of such substance in
such food does not ordinarily render it injurious to health;  or (2)(A)
if it bears or contains any added poisonous or added deleterious
substance (other than a substance that is a pesticide chemical resi-
due in or on a raw agricultural commodity or processed food, a food
additive, a color additive,  or  a  new  animal drug)  that is unsafe
within the meaning of section 406;  or (B) if it bears or contains a
pesticide chemical residue that is unsafe within the meaning of sec-
tion 408(a); or (C) if it is or if it bears or contains (i) any food addi-
tive that is unsafe within the meaning of section 409; or (ii)  a new
  1 The amendments made by section 3(i) of the "Nutrition Labeling and Education Act Amend-
ments of 1993" (P.L. 103-80) were based on incorrect form and consequently are not reflected.

     135

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Sec. 402	FEDERAL FOOD,  DRUG, AND COSMETIC ACT	136

animal drug (or conversion product thereof) that  is unsafe within
the meaning of section 512; or (3) if it consists in  whole or in part
of any filthy, putrid, or decomposed substance, or  if it is otherwise
unfit for food; or (4) if it has  been prepared, packed, or held under
insanitary  conditions whereby it may have become contaminated
with filth,  or whereby it may have  been rendered  injurious to
health; or (5) if it is, in whole or in part, the product of a diseased
animal or of an animal which has died otherwise than by slaugh-
ter; or (6) if its container is composed, in whole or in part, of any
poisonous or deleterious  substance which may render  the contents
injurious to health; or (7) if it has been intentionally subjected to
radiation, unless the use of the  radiation was in conformity with
a regulation or exemption in effect pursuant to section 409.
    (b)(l) If any valuable constituent has been in  whole or in part
omitted or  abstracted therefrom; or (2) if any substance has been
substituted wholly or in  part therefor; or (3) if damage or  inferior-
ity has been concealed in any manner; or (4) if any substance has
been added thereto or mixed  or packed therewith  so as to  increase
its bulk or  weight, or reduce its quality or strength, or make it ap-
pear better or of greater value than it is.
    (c) If it is, or it bears or contains, a color additive  which is un-
safe within the meaning of section 721(a).
    (d) If it is confectionery, and—
        (1) has partially or completely imbedded therein any non-
    nutritive object, except that this subparagraph shall not apply
    in the  case of any nonnutritive object if, in the judgment of the
    Secretary as provided by regulations, such object is of practical
    functional value  to  the confectionery product and would not
    render the product injurious or hazardous to health;
        (2) bears or contains any alcohol other than alcohol not in
    excess  of one-half of 1 per centum by volume derived solely
    from the use of flavoring extracts, except that this clause shall
    not apply to confectionery which is introduced or  delivered for
    introduction into, or received or  held for sale in, interstate
    commerce if the sale of such confectionery is  permitted under
    the laws of the State in which such confectionery is intended
    to be offered for sale; or
        (3) bears  or contains any nonnutritive substance, except
    that this  subparagraph shall not apply to a safe  nonnutritive
    substance which is in or on  confectionery by  reason of its use
    for some practical functional purpose in the manufacture, pack-
    aging,  or storage of such confectionery if the use of the sub-
    stance does not promote  deception of the consumer or other-
    wise result in adulteration or  misbranding in violation of any
    provision of this Act,  except that the  Secretary may, for the
    purpose of avoiding  or resolving uncertainty as to the applica-
    tion of this subparagraph, issue regulations allowing or prohib-
    iting the use of particular nonnutritive substances.
    (e) If it is oleomargarine  or margarine or butter and any of the
raw material used therein consisted  in  whole or in part of any
filthy, putrid, or decomposed substance, or such  oleomargarine or
margarine  or butter is otherwise unfit for food.
    (f)(l) If it is a dietary supplement or contains a dietary ingredi-
ent that—

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137	FEDERAL FOOD, DRU6, AND COSMETIC ACT	Sec. 403

        (A) presents a significant or unreasonable risk of illness or
    injury under—
            (i) conditions of use recommended or suggested in la-
        beling, or
            (ii) if no  conditions of  use are  suggested  or  rec-
        ommended in the labeling, under ordinary conditions of
        use;
        (B) is  a  new  dietary ingredient for which there  is inad-
    equate information to provide reasonable assurance that such
    ingredient  does not present a significant or unreasonable  risk
    of illness or injury;
        (C) the Secretary declares to pose an imminent hazard to
    public health or safety, except that the authority to make such
    declaration shall  not  be delegated  and the  Secretary shall
    promptly after such a declaration initiate  a proceeding in ac-
    cordance with sections  554 and 556 of title 5, United States
    Code, to affirm or withdraw the declaration; or
        (D) is or contains a dietary ingredient that renders it adul-
    terated under paragraph (a)(l) under the conditions of use rec-
    ommended or suggested in the labeling of such dietary supple-
    ment.
In  any proceeding under  this  subparagraph, the  United States
shall bear the burden of proof on each element to show that a die-
tary supplement  is adulterated. The court shall decide any issue
under this paragraph on a de novo basis.
    (2) Before the Secretary may report to a United States  attorney
a violation of paragraph (1)(A) for a  civil proceeding, the person
against whom such proceeding would be initiated shall be given ap-
propriate  notice and the opportunity to  present views, orally  and
in writing, at least 10  days before such notice, with regard to such
proceeding.
    (g)(l) If it  is a dietary supplement and it has been prepared,
packed, or held under conditions that do not meet current good
manufacturing practice regulations, including regulations requir-
ing, when necessary, expiration date labeling, issued by  the  Sec-
retary under subparagraph (2).
    (2) The Secretary  may by regulation prescribe  good manufac-
turing practices for dietary supplements.  Such regulations shall be
modeled after current  good manufacturing practice  regulations for
food and may not impose standards for  which there is no current
and generally available analytical methodology. No standard of cur-
rent good  manufacturing practice may  be  imposed unless  such
standard is included in a regulation promulgated after notice  and
opportunity for comment in  accordance  with chapter 5 of title 5,
United States Code.

                       MISBRANDED FOOD

    SEC. 403. [343] A food shall be deemed to be misbranded—
    (a) If (1) its labeling is false or misleading in any particular,
or (2) in the case of a food to which section 411 applies, its adver-
tising is false or misleading in a material respect or its labeling is
in violation of section 411(b)(2).
    (b) If it is offered for sale under the name of another food.

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Sec. 403	FEDERAL FOOD,  DRUG, AND COSMETIC ACT	138

    (c) If it is an imitation of another food, unless its label bears,
in type of uniform size and prominence, the word "imitation" and,
immediately thereafter, the name of the food imitated.
    (d) If its container is so  made, formed, or filled as to be mis-
leading.
    (e) If in package form unless it bears a label containing (1) the
name and  place of business  of the manufacturer, packer, or  dis-
tributor;  and (2) an accurate statement of the quantity of the con-
tents in terms of weight, measure, or numerical count, except that
under clause (2) of this  paragraph reasonable variations  shall be
permitted,  and exemptions  as to small packages  shall be estab-
lished, by regulations prescribed by the Secretary.
    (f) If any word, statement, or other information required by or
under authority of this Act to appear on the label or labeling is not
prominently placed thereon  with such  conspicuousness  (as com-
pared with other words,  statements, designs, or devices, in the la-
beling) and in such terms as to render it likely to be read and un-
derstood  by the ordinary individual under customary conditions of
purchase and use.
    (g) If it purports to be or is represented as a  food for which a
definition and standard of identity has been prescribed by regula-
tions as provided by section 401, unless (1) it conforms to such defi-
nition and standard, and (2) its label bears the name  of the food
specified in the definition and standard, and, insofar as may be re-
quired by such regulations, the common names of optional ingredi-
ents (other than spices, flavoring, and coloring)  present in such
food.
    (h) If it purports to be or is represented  as—
        (1) a food for which a  standard of quality has been pre-
    scribed by regulations as provided by section 401, and its qual-
    ity falls below such standard,  unless its  label bears, in such
    manner and form as such regulations specify, a statement that
    it falls below such standard; or
        (2) a food for which  a standard or standards of fill of con-
    tainer have been prescribed by regulations as provided by sec-
    tion  401, and it falls below the standard of fill of container ap-
    plicable thereto, unless  its label bears, in such manner  and
    form as  such  regulations specify, a statement that it falls
    below such standard.
    (i) Unless its label bears (1) the common or usual name of the
food, if any there  be, and (2) in case it is  fabricated from two or
more ingredients, the common or usual name  of each such ingredi-
ent and  if the food purports  to be a beverage containing  vegetable
or fruit juice, a statement with appropriate prominence on the in-
formation panel of the total  percentage of  such fruit or  vegetable
juice contained in the food; except that spices, flavorings, and colors
not  required to be certified under section 721(c) unless sold as
spices, flavorings,  or such  colors, may be designated  as spices,
flavorings, and colorings without naming each. To the  extent that
compliance with the requirements of clause (2) of this paragraph
is impracticable, or results in deception or  unfair  competition, ex-
emptions shall be established by regulations promulgated by the
Secretary.

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139	FEDERAL FOOD, DRUB, AND  COSMETIC  ACT	Sec. 403

    (j) If it purports to be or is represented for special dietary uses,
unless its label bears such information  concerning its vitamin, min-
eral, and other dietary  properties as the Secretary  determines to
be, and by regulations prescribes as, necessary in order fully to in-
form purchasers as to its value for such uses.
    (k) If it bears or contains any artificial  flavoring, artificial
coloring, or chemical preservative, unless it bears labeling stating
that fact, except  that to the extent that compliance with  the re-
quirements of this paragraph is impracticable, exemptions shall be
established by  regulations promulgated by the Secretary. The pro-
visions of this  paragraph and paragraphs (g) and (i) with  respect
to artificial coloring shall not apply in the case of butter,  cheese,
or ice  cream.  The provisions of this  paragraph with respect to
chemical preservatives shall not apply to  a pesticide chemical when
used in or on a raw agricultural commodity  which is the produce
of the soil.
    (1) If it is a raw agricultural commodity  which is the produce
of the  soil, bearing or containing a pesticide chemical applied after
harvest, unless the shipping container  of such commodity bears la-
beling  which declares the presence of such chemical  in or on such
commodity and the common or usual name and the function of
such chemical, except that no  such declaration shall  be required
while such commodity, having been removed from the shipping con-
tainer, is being held or displayed for sale at retail out of such con-
tainer  in accordance with the custom of the trade.
    (m) If it is a  color additive, unless its packaging and labeling
are in  conformity with such packaging and labeling  requirements,
applicable  to such  color  additive, as may be contained in  regula-
tions issued under section 721.
    (n) If its packaging or labeling is in  violation of an applicable
regulation issued  pursuant to section 3 or 4 of the Poison Preven-
tion Packaging Act of 1970.
    (o)(l) If it contains  saccharin, unless, except as  provided in
subparagraph (2), its label and labeling bear the following state-
ment:  "USE OF  THIS  PRODUCT MAY BE  HAZARDOUS  TO
YOUR  HEALTH.  THIS PRODUCT  CONTAINS  SACCHARIN
WHICH HAS  BEEN DETERMINED  TO CAUSE  CANCER IN
LABORATORY ANIMALS". Such statement  shall be located  in a
conspicuous place on such label and labeling as proximate  as pos-
sible to the name of such food and shall appear in conspicuous and
legible type in contrast by typography,  layout, and color with other
printed matter on such label and labeling.
    (2) The Secretary may by regulation review and revise or re-
move the requirement of subparagraph (1) if the Secretary deter-
mines  such action is necessary to reflect the current state of knowl-
edge concerning saccharin.
    [(p) Repealed by Pub. L. 104-124, April 1, 1996.]
    (q)(l) Except  as provided in subparagraphs (3), (4), and (5), if
it is a food intended for human  consumption and is offered for sale,
unless  its  label or labeling bears nutrition information that  pro-
vides—
        (A)(i) the serving  size which  is an amount  customarily
    consumed  and which is expressed  in a common household
    measure that is appropriate to the food, or

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Sec. 403	FEDERAL FOOD, DRUB, AND COSMETIC ACT	140

        (ii)  if the use of the food  is not typically expressed  in a
    serving size, the common household unit of measure that ex-
    presses the serving size of the food,
        (B) the  number of servings or other units of measure per
    container,
        (C) the total number of calories—
            (i) derived from any source, and
            (ii) derived from the total fat,
    in each serving size or other unit of measure of the food,
        (D) the  amount of the following nutrients: Total fat, satu-
    rated fat, cholesterol, sodium, total carbohydrates, complex car-
    bohydrates,  sugars, dietary fiber, and total protein contained in
    each serving size or other unit of measure,
        (E) any vitamin, mineral, or other nutrient required to be
    placed on the label and labeling of food under this Act before
    October 1, 1990, if the Secretary determines that such informa-
    tion will assist consumers in maintaining healthy dietary prac-
    tices.
The Secretary may by regulation require any information required
to be  placed on  the label or labeling by this subparagraph or sub-
paragraph (2)(A) to be highlighted on the label or labeling by larger
type,  bold type, or contrasting color if the Secretary determines
that  such  highlighting  will  assist  consumers in  maintaining
healthy dietary practices.
    (2)(A) If the Secretary determines that a nutrient other  than
a nutrient required by subparagraph (1)(C), (1)(D), or (1)(E) should
be included in the label or labeling of food subject to subparagraph
(1) for purposes of providing information regarding the nutritional
value of  such food  that will  assist  consumers  in maintaining
healthy dietary practices, the Secretary may by regulation require
that information relating to such additional nutrient be included in
the label or labeling of such food.
    (B)  If the Secretary determines that the information relating to
a  nutrient  required  by subparagraph (1)(C), (1)(D), or (1)(E) or
clause (A) of this subparagraph to be included in the label or label-
ing of food is not necessary to assist  consumers in maintaining
healthy dietary practices, the Secretary may by regulation remove
information relating to such nutrient from such requirement.
    (3)  For food that is  received in bulk containers at a retail es-
tablishment, the Secretary may, by regulation, provide that the nu-
trition information required by subparagraphs  (1) and (2) be dis-
played at the location in the retail establishment at which the food
is offered for sale.
    (4)(A) The Secretary shall provide for furnishing the nutrition
information required by subparagraphs (1) and (2) with  respect to
raw agricultural commodities and raw fish by issuing voluntary nu-
trition guidelines, as provided by clause (B) or by issuing regula-
tions  that are mandatory as provided by clause (D).
    (B)(i) Upon  the  expiration of 12 months  after the date of the
enactment of the  Nutrition Labeling and Education Act of 1990 *,
the Secretary, after providing an opportunity for comment,  shall
issue  guidelines  for food  retailers offering raw agricultural  com-
  lThe date is November 8, 1991.

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141	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 403

modities or raw fish to provide nutrition information specified in
subparagraphs (1) and (2). Such guidelines shall take into account
the actions taken by food retailers during such 12-month period to
provide to consumers  nutrition information on  raw  agricultural
commodities and raw fish. Such guidelines shall only apply—
        (I) in the case of raw agricultural commodities, to the 20
    varieties  of vegetables most frequently consumed during a year
    and the 20 varieties of fruit most frequently  consumed during
    a year, and
        (II)  to  the 20  varieties  of  raw  fish  most  frequently
    consumed during a year.
The vegetables, fruits, and raw fish to which such guidelines apply
shall  be  determined by the Secretary by regulation and the Sec-
retary may apply such guidelines regionally.
    (ii) Upon the expiration of 12 months after the date of the en-
actment of the Nutrition Labeling and Education  Act of 19901, the
Secretary shall issue a final regulation defining the circumstances
that constitute substantial compliance by food retailers with the
guidelines issued under subclause (i). The regulation shall  provide
that there is  not substantial compliance if a significant number of
retailers have failed to comply with the guidelines.  The size of the
retailers and the portion of the market served by retailers  in com-
pliance  with the  guidelines  shall  be  considered in determining
whether the substantial-compliance standard has been met.
    (C)(i) Upon the expiration of 30 months after the date of the
enactment of the Nutrition Labeling and Education Act of 19902,
the Secretary shall issue a report on actions taken by food retailers
to provide consumers with nutrition information for raw  agricul-
tural  commodities and raw fish  under the guidelines issued under
clause (A). Such  report shall  include a determination of whether
there  is substantial compliance with the guidelines.
    (ii) If the Secretary finds  that there is substantial compliance
with the guidelines, the Secretary shall issue a report and  make a
determination of the type required in subclause (i) every two years.
    (D)(i) If the Secretary determines that there is  not substantial
compliance with  the guidelines  issued under clause (A), the Sec-
retary shall at the time such determination is made issue proposed
regulations requiring that any person who offers raw agricultural
commodities  or raw fish to consumers provide, in  a  manner pre-
scribed by regulations, the nutrition information  required  by sub-
paragraphs (1)  and (2).  The Secretary shall issue final regulations
imposing such requirements 6 months after issuing the proposed
regulations. The final regulations shall become effective 6  months
after the date of their promulgation.
    (ii) Regulations issued under subclause (i) may require that the
nutrition information required by subparagraphs (1) and (2) be pro-
vided for more than 20 varieties of vegetables, 20 varieties  of fruit,
and 20 varieties of fish most frequently consumed during a year if
the Secretary finds that a larger number of such products  are fre-
quently consumed. Such regulations shall permit  such information
to be  provided in a single location in each area in which raw agri-
  1The date is November 8, 1991.
  2 The date is May 8, 1993.

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Sec. 403	FEDERAL FOOD, DRUB, AND  COSMETIC ACT	142

cultural commodities and raw fish are offered for sale. Such regula-
tions may provide that information shall be expressed as an aver-
age or range per serving of the same type of raw agricultural com-
modity or raw fish. The Secretary shall develop and make available
to the persons who offer such food to consumers the information re-
quired by subparagraphs (1) and (2).
    (iii) Regulations issued under subclause (i) shall permit the re-
quired information to be provided in each area of an establishment
in which raw agricultural commodities and raw fish are offered for
sale. The regulations shall permit food retailers to display the re-
quired information by supplying copies of the information provided
by the Secretary, by making the information available in brochure,
notebook or leaflet form, or by posting a sign disclosing the infor-
mation.  Such regulations shall also permit presentation of the re-
quired information to be supplemented by a video, live demonstra-
tion, or other media which the Secretary approves.
    (E) For purposes of this subparagraph, the term "fish" includes
freshwater or marine fin fish, crustaceans, and mollusks, including
shellfish, amphibians, and other forms of aquatic animal life.
    (F) No person who offers raw agricultural commodities or raw
fish to consumers may  be prosecuted  for minor violations of this
subparagraph if there has been substantial compliance with the re-
quirements of this paragraph.
    (5)(A)  Subparagraphs (1), (2),  (3),  and (4) shall  not apply to
food—
        (i) which is served in restaurants or  other establishments
    in which food is served for  immediate human  consumption or
    which is sold for sale or use  in such establishments,
        (ii) which is processed and prepared  primarily in a retail
    establishment, which is ready for human consumption, which
    is of the type described in  subclause (i),  and which is offered
    for sale to consumers but not for immediate human consump-
    tion in such establishment and which is not  offered for sale
    outside such establishment,
        (iii) which is an infant formula subject to section 412,
        (iv) which is a medical food as defined in section 5(b) of the
    Orphan Drug Act (21 U.S.C. 360ee(b)), or
        (v) which is described in section 405(2).
    (B)  Subparagraphs  (1) and  (2) shall not  apply to the label of
a food if the Secretary determines by regulations that compliance
with such  subparagraphs is impracticable because the package of
such food is too small to comply with the requirements of such sub-
paragraphs and if the label of such food does not contain any nutri-
tion information.
    (C)  If a food contains insignificant amounts, as determined by
the Secretary, of  all  the  nutrients required by subparagraphs  (1)
and (2) to be listed in the label or labeling of food, the require-
ments of such subparagraphs shall not apply to such food  if the
label, labeling, or advertising of such food does not make any claim
with respect to the nutritional value of such food. If a food contains
insignificant amounts,  as determined  by  the Secretary,  of more
than  one-half the nutrients required by subparagraphs (1) and  (2)
to be in the label or labeling of the food, the Secretary shall require

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143	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 403

the amounts of such nutrients to be stated in a. simplified form pre-
scribed by the Secretary.
    (D) If a person offers food for sale and has annual gross sales
made or business done in  sales to  consumers which  is not more
than $500,000 or has annual gross sales made or business done in
sales of food to consumers which is not more than $50,000, the re-
quirements of subparagraphs (1), (2), (3), and (4) shall not  apply
with respect to food sold by such person to consumers unless  the
label or labeling of food offered by such person provides nutrition
information or makes a nutrition claim.
    (E)(i) During the 12-month period for which an exemption from
subparagraphs (1) and (2)  is claimed pursuant to this subclause,
the requirements of such subparagraphs shall not apply to any food
product if—
        (I) the labeling for  such product does not provide nutrition
    information or make a claim subject to paragraph (r),
        (II) the person who claims for such product an exemption
    from such subparagraphs employed fewer than an average of
    100 full-time equivalent employees,
        (III)  such person  provided the  notice described  in  sub-
    clause (iii), and
        (IV) in the case of a food product which was sold in the 12-
    month period preceding the period for which an exemption was
    claimed, fewer than 100,000 units of such product  were sold in
    the United States during such preceding period, or in the case
    of a food product which was not sold in the 12-month period
    preceding the period  for  which such exemption is  claimed,
    fewer than 100,000 units of such product are reasonably antici-
    pated to  be sold in the United  States during the period for
    which such exemption is claimed.
    (ii) During the 12-month period after the applicable date re-
ferred  to in this sentence,  the requirements of subparagraphs (1)
and (2) shall not apply to any food  product which was first intro-
duced into interstate commerce before May 8, 1994, if the labeling
for such product does not provide nutrition information or make a
claim subject to paragraph (r), if such person provided the notice
described in subclause (iii),  and if—
        (I)  during the 12-month period preceding May 8, 1994, the
    person  who  claims for  such product  an  exemption from such
    subparagraphs employed fewer  than an  average  of 300 full-
    time equivalent  employees and fewer than  600,000  units of
    such product were sold  in the United States,
        (II) during the 12-month period preceding May 8, 1995, the
    person  who  claims for  such product  an  exemption from such
    subparagraphs employed fewer  than an  average  of 300 full-
    time equivalent  employees and fewer than  400,000  units of
    such product were sold in the United States, or
        (III) during the 12-month period preceding May 8,  1996,
    the person who  claims for such product  an  exemption from
    such subparagraphs employed fewer than an average of 200
    full-time equivalent employees and fewer than 200,000  units of
    such product were sold in the United States.
    (iii) The notice referred to  in subclauses (i) and  (ii)  shall be
given to the Secretary prior to the beginning  of the period during

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Sec. 403	FEDERAL FOOD, DRUG,  AND COSMETIC ACT	144

which the exemption under subclause (i) or (ii)  is to be in effect,
shall state that the  person claiming such exemption for a food
product has complied with the applicable requirements of subclause
(i) or (ii), and shall—
        (I) state the average number of full-time equivalent em-
    ployees such person employed  during the 12 months preceding
    the date such person claims such exemption,
        (II) state  the approximate  number of  units  the person
    claiming the exemption sold in the United States,
        (III) if the exemption is claimed for a food product which
    was sold in the 12-month period preceding the period for which
    the exemption was claimed, state the approximate number of
    units of such  product which were  sold in the United  States
    during such preceding period,  and, if the exemption is claimed
    for a food product which was not sold in such preceding period,
    state the number of units of such product which such person
    reasonably anticipates will be sold in the United States during
    the period for which the exemption was claimed, and
        (IV) contain  such information as the Secretary may require
    to verify the information required by the preceding provisions
    of this subclause if the Secretary has  questioned the validity
    of such information.
If a person is not an importer, has fewer than 10 full-time equiva-
lent employees, and sells fewer than 10,000 units of any food prod-
uct in any year, such person is not required to file a notice for such
product under this subclause for such year.
    (iv) In the case  of a person who claimed an exemption under
subclause (i) or (ii),  if,  during the period of such exemption, the
number of full-time  equivalent employees of such person exceeds
the number in such subclause  or if the number of food products
sold in  the United States exceeds the number in  such subclause,
such exemption shall extend to the  expiration of 18 months after
the date the number of full-time equivalent employees or food prod-
ucts sold exceeded the applicable number.
    (v)  For any food product first introduced into interstate com-
merce after May 8,  2002, the Secretary may  by regulation  lower
the employee or units of food products requirement of subclause (i)
if the Secretary determines that the cost of compliance with such
lower requirement will not place an undue burden on persons sub-
ject to such lower requirement.
    (vi) For purposes of subclauses (i), (ii), (iii), (iv), and (v)—
        (I) the term "unit" means the packaging or, if there is no
    packaging, the form  in which a food product is offered for sale
    to consumers,
        (II) the term "food product" means food in any sized pack-
    age which is manufactured by a single manufacturer or which
    bears the  same brand name, which bears the  same statement
    of identity, and which has similar preparation methods, and
        (III) the term "person" in the case of a corporation includes
    all domestic and foreign affiliates of the corporation.
    (F)  A dietary  supplement product (including a food to which
section 411 applies) shall comply with the requirements of subpara-
graphs (1) and (2) in a manner which is  appropriate for the product

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145	FEDERAL FOOD, DRUB. AND COSMETIC ACT	Sec. 403

and which is specified in regulations of the Secretary which shall
provide that—
        (i) nutrition information shall first list those dietary ingre-
    dients that are present in the product in a significant amount
    and for which a  recommendation for daily consumption has
    been established by the Secretary, except that a dietary ingre-
    dient shall not be required to be listed if it is not  present in
    a significant amount, and shall list any other dietary ingredi-
    ent present and identified as having no such recommendation;
        (ii) the  listing of  dietary  ingredients shall include the
    quantity of each such ingredient (or of a proprietary blend of
    such ingredients) per serving;
        (iii) the listing of dietary  ingredients  may include the
    source of a dietary ingredient; and
        (iv) the nutrition information shall  immediately precede
    the ingredient information required under subclause (i), except
    that no ingredient identified pursuant to subclause (i) shall be
    required to be identified a second time.
    (G) Subparagraphs (1),  (2), (3), and  (4) shall not apply to food
which is sold by a food distributor if the food distributor  principally
sells food to restaurants or other establishments  in which food is
served for immediate  human consumption and does not manufac-
ture, process, or repackage the food it sells.
    (r)(l) Except as provided in clauses (A) through (C) of subpara-
graph (5), if it is a food intended for human consumption which is
offered for sale and for which a claim is made in the label or label-
ing of the food which expressly or by implication—
        (A) characterizes  the level of any  nutrient which is of the
    type required by paragraph (q)(l) or (q)(2) to be in the label or
    labeling of the  food unless  the claim is made  in accordance
    with subparagraph (2), or
        (B) characterizes the relationship  of any nutrient which is
    of the  type required by paragraph (q)(l) or (q)(2) to be in the
    label or labeling of the  food to a disease or a health-related
    condition unless the claim is made in accordance with subpara-
    graph (3) or (5)(D).
A statement of the type required by paragraph (q) that appears as
part of the nutrition  information required or permitted by such
paragraph is not a claim which is subject  to this paragraph and a
claim subject to clause  (A) is not subject to  clause (B).
    (2)(A)  Except as  provided  in  subparagraphs  (4)(A)(ii) and
(4)(A)(iii) and clauses (A) through (C) of subparagraph (5), a claim
described in subparagraph (1)(A)—
        (i) may be made  only if the characterization of the level
    made in the claim  uses terms which are defined in regulations
    of the Secretary,
        (ii) may not state the absence of a nutrient unless—
            (I) the  nutrient is usually present in the food or in a
        food which substitutes for the food as defined by the Sec-
        retary by regulation, or
            (II) the  Secretary  by regulation permits such a state-
        ment on the basis of a finding that such a statement would
        assist consumers in maintaining healthy dietary practices

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Sec. 403	FEDERAL  FOOD, DRUG, AND COSMETIC ACT	146

        and the statement discloses that the nutrient is not usu-
        ally present in the food,
        (iii) may not be made with respect to the level of choles-
    terol in the food if the food contains, as determined by the Sec-
    retary by regulation, fat or saturated fat in an amount which
    increases  to persons in the general population the risk  of dis-
    ease or a health related condition which is diet  related un-
    less—
            (I) the Secretary finds by regulation that  the level of
        cholesterol is substantially less than  the  level usually
Eresent in the food or in a food which substitutes for the
         )od  and which has a significant market share, or the Sec-
        retary by regulation permits a statement regarding the ab-
        sence of cholesterol  on the  basis of a finding that choles-
        terol is not usually present in the food and that such a
        statement would assist consumers  in maintaining healthy
        dietary  practices  and a requirement that the statement
        disclose that cholesterol is not usually present in the food,
        and
            (II) the label or labeling of the food discloses the level
        of such fat or saturated fat in immediate proximity to such
        claim and with  appropriate prominence which shall be no
        less than one-half the size of the claim with respect to the
        level of cholesterol,
        (iv) may not be made with respect to the level of saturated
    fat in the food if the food contains cholesterol unless the label
    or labeling of the food discloses  the level of cholesterol in the
    food in immediate  proximity to such  claim and with  appro-
    priate prominence which shall be no less than one-half the size
    of the claim with respect to the level of  saturated fat,
        (v) may not state that a food is high in dietary fiber unless
    the food  is low in total fat as defined by the Secretary or the
    label  or labeling discloses the  level of  total fat in the food in
    immediate proximity to such statement and with  appropriate
    prominence which shall be no less than one-half the size of the
    claim with respect to the level of dietary fiber, and
        (vi) may not be made if the Secretary  by regulation pro-
    hibits the claim because the claim is misleading in light of the
    level of another nutrient in the food.
    (B) If a claim described in subparagraph (1)(A) is made with
respect to a nutrient in a food,  the label or labeling of such food
shall contain, prominently and in immediate proximity to such
claim, the following statement: "See	for nutrition in-
formation." In the statement—
        (i) the blank shall identify the panel on which the informa-
    tion described in the statement may be  found, and
        (ii) if the Secretary determines that the food contains a nu-
    trient at a level which increases to persons in the general pop-
    ulation the risk of  a disease or health-related condition which
    is diet related, taking into account the significance of the food
    in the total daily diet, the statement  shall also identify such
    nutrient.
    (C) Subparagraph (2)(A) does not apply to a claim described in
subparagraph (1)(A) and contained in the label or labeling of a food

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147	FEDERAL FOOD, DRUG. AND COSMETIC ACT	Sec. 403

if such claim is contained in the brand name of such food and such
brand name was in use on such food before October 25,  1989, un-
less the brand  name contains a term  defined  by the  Secretary
under subparagraph (2)(A)(i).  Such a claim is subject to paragraph
(a).
    (D) Subparagraph (2) does not apply to  a claim described in
subparagraph (1)(A) which uses the term "diet" and is contained in
the label or labeling of a soft drink if (i) such claim is  contained
in the brand name of such soft drink, (ii) such brand name was in
use on such soft drink before  October 25, 1989, and (iii) the use of
the term "diet" was in conformity with section 105.66 of title 21 of
the Code of Federal Regulations. Such a claim is subject to para-
graph (a).
    (E) Subclauses (i) through (v) of subparagraph (2)(A) do not
apply to a statement in the label or labeling of food which describes
the percentage of vitamins and minerals in the food in relation to
the amount of such vitamins  and minerals recommended for daily
consumption by the Secretary.
    (F)  Subclause (i) clause (A)  does not apply to a statement in
the labeling of a dietary supplement that characterizes the percent-
age level of a dietary ingredient for which the Secretary has not es-
tablished  a reference daily intake, daily recommended  value, or
other recommendation for daily consumption.
    (3)(A) Except as provided in  subparagraph  (5),  a  claim  de-
scribed in subparagraph (1)(B) may only  be made—
        (i) if the claim meets  the requirements of the regulations
    of the Secretary promulgated under clause (B), and
        (ii) if the food for which the claim is made does not con-
    tain, as determined by the Secretary by regulation, any nutri-
    ent in an amount which  increases  to persons  in  the general
    population the risk of a  disease or health-related  condition
    which is diet related, taking into account the significance of
    the food in the total daily diet, except that the Secretary may
    by regulation permit such a claim based on a finding that such
    a claim would assist consumers in maintaining healthy dietary
    practices and based on a  requirement that the label  contain a
    disclosure of the type required by subparagraph (2)(B).
    (B)(i)  The Secretary shall promulgate regulations  authorizing
claims of the type described in subparagraph (1)(B) only if the Sec-
retary determines,  based on the totality of publicly available sci-
entific evidence (including evidence from well-designed studies con-
ducted in a manner which is  consistent with generally recognized
scientific procedures  and principles), that there  is  significant sci-
entific agreement,  among experts  qualified by scientific training
and experience to evaluate such claims, that the claim is supported
by such evidence.
    (ii) A regulation described in subclause (i) shall describe—
        (I) the relationship between a nutrient of the type required
    in the label or labeling of food by paragraph (q)(l) or (q)(2) and
    a disease or health-related condition, and
        (II) the significance of each such nutrient in affecting such
    disease or health-related condition.
    (iii) A regulation described in subclause (i) shall require such
claim to be stated in a manner so that the claim is an accurate rep-

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Sec. 403	FEDERAL FOOD. DRUG. AND COSMETIC ACT	148

resentation of the matters set out in subclause (ii) and so that the
claim enables the public to comprehend the information provided in
the claim and to understand the relative significance of such infor-
mation in the context of a total daily diet.
    (4)(A)(i) Any person may petition the Secretary to issue  a regu-
lation under subparagraph (2)(A)(i) or (3)(B) relating to a claim  de-
scribed in subparagraph (1)(A) or (1)(B). Not later than 100 days
after the petition is received by the Secretary, the Secretary shall
issue  a final decision denying the petition or file the  petition  for
further action by the Secretary. If the Secretary denies the petition,
the petition shall not be made available to the public. If the Sec-
retary files the petition, the Secretary shall  deny the petition or
issue a proposed regulation to take the action requested in the peti-
tion not later than 90 days after the date of such decision.
    (ii) Any person may  petition the  Secretary  for  permission to
use in a claim described in subparagraph (1)(A) terms that are con-
sistent with the  terms defined by the Secretary under subpara-
graph (2)(A)(i). Within 90 days of the submission of such a petition,
the Secretary shall issue a final  decision denying the petition or
granting such permission.
    (iii) Any person may petition the Secretary  for permission to
use an implied claim described in subparagraph (1)(A) in a brand
name. After publishing notice of an opportunity to comment on the
petition in the Federal Register and making the petition available
to the public, the Secretary shall grant the petition if the Secretary
finds  that such claim is not  misleading and is consistent with
terms defined by the Secretary under subparagraph (2)(A)(i). The
Secretary shall grant or deny the petition within 100  days of  the
date it is submitted to the Secretary and the  petition shall  be con-
sidered granted if the Secretary does not act on it within such 100
days.
    (B) A petition under clause (A)(i) respecting a claim described
in subparagraph (1)(A) or (1)(B) shall include  an explanation of  the
reasons why the  claim meets the requirements of this paragraph
and a summary of the scientific data which supports such reasons.
    (C) If a petition for a regulation under subparagraph (3)(B) re-
lies on a report from an  authoritative  scientific body of the United
States, the Secretary shall  consider such report  and shall justify
any decision rejecting the conclusions of such report.
    (5)(A) This paragraph does not apply to infant formulas subject
to section 412(h) and medical foods as defined in section 5(b) of  the
Orphan Drug Act.
    (B) Subclauses  (iii) through (v) of subparagraph (2)(A) and sub-
paragraph (2)(B) do not apply  to  food  which is  served  in res-
taurants or other establishments  in which food is served for imme-
diate  human consumption or which is sold for sale or  use  in such
establishments.
    (C) A subparagraph (1)(A) claim made with  respect to a food
which claim is required by a standard of identity  issued under sec-
tion 401 shall not be subject to subparagraph (2)(A)(i) or (2)(B).
    (D) A subparagraph (1)(B) claim made with respect to a dietary
supplement  of vitamins,  minerals, herbs, or other  similar nutri-
tional substances shall not be subject to subparagraph (3) but shall

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149	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 403

be subject to a procedure and standard, respecting the validity of
such claim, established by regulation of the Secretary.
    (6) For purposes of paragraph (r)(l)(B), a statement for a die-
tary supplement may be made if—
        (A) the statement claims a benefit related to a classical nu-
    trient deficiency disease and discloses the prevalence of such
    disease in the United States, describes the role  of a nutrient
    or dietary ingredient intended to affect the structure or func-
    tion  in humans, characterizes the documented mechanism by
    which a nutrient or dietary ingredient acts  to maintain such
    structure or function, or describes general well-being from con-
    sumption of a nutrient or dietary ingredient,
        (B) the  manufacturer of the  dietary supplement has sub-
    stantiation that such statement is truthful and not misleading,
    and
        (C) the  statement contains, prominently displayed and in
    boldface type, the following: 'This statement has not been eval-
    uated by the Food  and Drug Administration. This product is
    not intended to diagnose, treat, cure, or prevent any disease.".
A statement under this subparagraph may not  claim to diagnose,
mitigate, treat, cure, or  prevent a specific disease or class of dis-
eases.  If the manufacturer of a dietary supplement proposes  to
make a statement described in the first sentence of this subpara-
graph in the labeling of the dietary supplement,  the manufacturer
shall notify the Secretary no later than 30 days after the first mar-
keting of the dietary supplement with such statement that such a
statement is being made.
    (s) If—
        (1) it is a dietary supplement; and
        (2)(A) the label or labeling of the supplement fails to list—
           (i) the name of each ingredient of the supplement that
        is described in section 201(ff); and
           (ii)(I) the quantity of each such ingredient; or
           (II) with respect to a proprietary blend of such ingredi-
        ents, the total quantity of all ingredients  in the blend;
        (B) the label or labeling of the dietary supplement fails to
    identify the product by using the term "dietary  supplement",
    which term may be modified with the name of such an ingredi-
    ent;
        (C) the  supplement contains an ingredient  described  in
    section 201(ff)(l)(C), and the label or labeling of the supple-
    ment fails to identify any part of the plant from which the in-
    gredient is derived;
        (D) the supplement—
           (i) is covered by the specifications of an official com-
        pendium;
           (ii) is represented as conforming  to  the  specifications
        of an official compendium; and
           (iii)  fails to so conform; or
        (E) the supplement—
           (i) is not covered by the specifications of an official
       compendium; and
           (ii)(I) fails to have the identity and  strength that the
        supplement is represented to have; or

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Sec. 403A	FEDERAL FOOD. DRUG. AND COSMETIC  ACT	150

            (II) fails to meet the quality (including tablet or cap-
        sule disintegration), purity, or compositional specifications,
        based  on validated assay or other appropriate methods,
        that the supplement is represented to meet.
A dietary supplement shall not  be  deemed misbranded solely be-
cause its label or labeling contains directions or conditions of use
or warnings.
    SEC. 403A. [343—1] (a) Except as provided in subsection (b), no
State or political subdivision  of a State may directly or indirectly
establish under any authority or continue in effect as to any food
in interstate commerce—
        (1)  any requirement  for a food which  is the subject of  a
    standard of identity established under section 401  that is not
    identical to such standard of identity or that is not identical to
    the requirement of section 403(g), except that this paragraph
    does not apply to a standard of identity of a State  or political
    subdivision of a  State for maple syrup  that is  of the type re-
    quired by sections 401 and 403(g),
        (2)  any requirement for the labeling of food of the type re-
    quired by  section 403(c), 403(e), or 403(i)(2) that is not iden-
    tical to the requirement of such section, except that this para-
    graph does not  apply to  a requirement of  a State  or political
    subdivision of a State  that is of the type required by section
    403(c) and that is applicable  to maple syrup,
        (3)  any requirement for the labeling of food of the type re-
    quired  by section 403(b), 403(d),  403(f>, 403(h), 403(i)(l), or
    403(k) that is not identical to the requirement of such section,
    except that this paragraph does not apply to a requirement of
    a State or political subdivision of a State that is of the type re-
    quired  by section 403(h)(l)  and  that  is applicable to maple
    syrup,
        (4)  any requirement  for nutrition  labeling of food that is
    not identical to  the requirement of section  403(q), except a re-
    quirement for nutrition labeling of food which is exempt under
    subclause (i) or (ii) of section 403(q)(5)(A), or
        (5)  any requirement  respecting any claim of the type de-
    scribed in section 403(r)(l) made in the label or labeling of food
    that is not identical to the requirement of section 403(r), except
    a requirement respecting a claim made in the label or labeling
    of food which is exempt under section 403(r)(5)(B).
Paragraph (3) shall take effect in accordance with section 6(b) of
the Nutrition Labeling and Education Act of 1990.
    (b) Upon petition of a State or a political subdivision of a State,
the Secretary may exempt from subsection (a), under such  condi-
tions as may be  prescribed by  regulation, any State or local re-
quirement that—
        (1) would not cause any food to be in violation of any appli-
    cable requirement under Federal law,
        (2) would not unduly burden interstate commerce, and
        (3) is designed to address a particular need for information
    which need is not met by the requirements of the  sections re-
    ferred to in subsection (a).

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151	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 404

           DIETAEY SUPPLEMENT LABELING EXEMPTIONS

    SEC. 403B. f 343-2J (a) IN GENERAL.—A publication, including
an article, a  chapter in a book, or an official abstract of a peer-re-
viewed scientific publication that appears in an article and  was
prepared by  the author or the editors of the publication, which is
reprinted in its entirety, shall not be defined as labeling when used
in connection with the sale of a  dietary supplement to consumers
when it—
        (1) is not false or misleading;
        (2) does not promote a particular manufacturer or brand of
    a dietary supplement;
        (3) is displayed or presented, or  is displayed or presented
    with other such items  on the same subject matter, so as to
    present a balanced view of the available scientific information
    on a dietary supplement;
        (4) if displayed in an establishment, is physically separate
    from the dietary supplements; and
        (5) does not have appended to it any information by sticker
    or any other method.
    (b) APPLICATION.—Subsection (a) shall not apply to or restrict
a retailer or wholesaler of dietary supplements in any way whatso-
ever in the sale of books or other publications as a part of the busi-
ness of such retailer or wholesaler.
    (c) BURDEN OF PROOF.—In any proceeding brought under sub-
section (a), the burden of proof shall be on the United States to es-
tablish that an article or other such matter is false or misleading.

                  EMERGENCY PERMIT CONTROL

    SEC. 404. [344] (a) Whenever the Secretary finds after inves-
tigation that the distribution in  interstate commerce of any class
of food may, by reason of contamination with micro-organisms dur-
ing the manufacture, processing,  or packing thereof in any locality,
be injurious  to health, and that such injurious nature cannot be
adequately determined after such articles have entered interstate
commerce, he then, and in such case only, shall promulgate regula-
tions  providing for the issuance, to manufacturers, processors, or
packers of such class of food in  such locality of permits to  which
shall be attached such conditions governing the manufacture, proc-
essing, or packaging of such class of food, for such temporary pe-
riod of time,  as may be necessary to protect the public health;  and
after the effective date of such regulations, and  during such tem-
porary period, no person shall introduce or deliver  for introduction
into interstate commerce any such food manufactured, processed,
or packed by any such manufacturer, processor, or packer unless
such manufacturer, processor, or packer holds a permit issued by
the Secretary as provided by such regulations.
    (b) The Secretary  is authorized to  suspend immediately upon
notice  any permit issued under  authority of this section if it is
found that any of the conditions  of the permit have been violated.
The holder of a permit so suspended shall be privileged at any time
to apply for  the reinstatement of such permit, and the Secretary
shall, immediately after prompt  hearing  and an inspection  of the
establishment, reinstate such permit if it is found that adequate

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Sec. 405	FEDERAL FOOD. DRUG, AND COSMETIC ACT	152

measures have been taken to comply with and maintain the condi-
tions of the permit, as originally issued or as amended.
    (c) Any officer or employee  duly designated by the Secretary
shall have access to any factory or establishment, the operator of
which  holds  a permit  from  the Secretary,  for the  purpose of
ascertaining whether or not the conditions of the permit are being
complied  with,  and denial  of access  for such inspection shall be
ground  for suspension of the permit until such access is freely
given by the operator.

                REGULATIONS MAKING EXEMPTIONS

    SEC.  405.  [3451 The Secretary shall  promulgate  regulations
exempting from any labeling requirement of this Act (1) small open
containers of fresh fruits and  fresh vegetables and (2) food which
is in accordance with the practice of the trade, to be processed, la-
beled, or repacked in substantial quantities at  establishments other
than those where originally processed or packed, or condition that
such food is not adulterated or misbranded under the provisions of
this Act upon removal from such processing, labeling, or repacking
establishment. This section does not apply to  the labeling require-
ments of sections 403(q) and 403(r).

        TOLERANCES FOR POISONOUS INGREDIENTS IN FOOD

    SEC. 406. [346] Any poisonous or deleterious substance added
to any food, except where such substance is required in the produc-
tion thereof or cannot be avoided by good manufacturing practice
shall be deemed to be  unsafe for purposes  of  the application of
clause (2)(A) of section 402(a); but when such substance is so re-
quired or cannot be so avoided, the Secretary shall promulgate reg-
ulations limiting the quantity  therein or thereon to such extent as
he  finds  necessary for  the  protection  of public health, and  any
quantity exceeding the limits  so fixed shall also be deemed to be
unsafe for purposes of the application of clause (2)(A) of section
402(a). While  such a regulation is in effect limiting the quantity of
any such  substance in the case of any food, such food shall not, by
reason of bearing  or containing any added amount of such sub-
stance,  be considered  to be adulterated within the meaning of
clause  (1) of section 402(a). In determining the quantity of such
added substance to be tolerated in or on different articles of food
the Secretary shall take into account the extent to which the use
of such  substance is required  or cannot be avoided in the produc-
tion of each such article, and the other ways in which the consumer
may be  affected by the same or other poisonous  or deleterious sub-
stances.

                 OLEOMARGARINE OR MARGARINE

    SEC.  407.  [347]l (a) Colored  oleomargarine or colored mar-
garine which is sold in  the same State or Territory in which it is
  'Public Law 81-459, March 16, 1950 (64 Stat. 20), amended section 15 of the Federal Trade
Commission Act by adding the following subsection:
  "(0 For the purposes of this section and section 407 of the Federal Food, Drug, and Cosmetic
Act, as amended, the term 'oleomargarine' or "margarine' includes—
    "(1) all substances, mixtures, and compounds known as oleomargarine or margarine;

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 153	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 407

 produced shall be subject in the same manner and to the same ex-
 tent  to the provisions of this Act as if it had been introduced in
 interstate commerce.
     (b) No person shall sell, or offer for sale, colored oleomargarine
 or colored margarine unless-j-
         (1) such oleomargarine or margarine is packaged,
         (2) the net weight of the contents of any package sold in
     a retail establishment is one pound or less,
         (3) there appears on the label of the  package (A) the word
     "oleomargarine" or "margarine" in type or lettering at least as
     large  as any other type or lettering on such label, and (B) a
     full and accurate statement of  all the ingredients contained in
     such oleomargarine, or margarine, and
         (4) each part  of the contents of the  package is contained
     in a wrapper which bears the  word "oleomargarine" or "mar-
     garine" in type or lettering not smaller than 20-point type.
 The requirements of this subsection shall be in addition to and not
 in lieu of any of the other requirements of this Act.
     (c) No  person shall possess  in a form ready for serving colored
 oleomargarine or colored margarine at a public eating place unless
 a notice  that oleomargarine or margarine is served  is displayed
 prominently and conspicuously  in such place and in such manner
 as to render it likely to be read  and understood by the ordinary in-
 dividual being served in such eating place or is printed or is other-
 wise set forth  on the menu in  type or lettering  not smaller than
 that normally used to designate the serving of other food items. No
 person shall serve colored oleomargarine or colored margarine at a
 public eating place, whether or not any charge  is made therefor,
 unless (1) each separate serving bears or is accompanied by label-
 ing identifying it as oleomargarine  or margarine, or (2) each sepa-
 rate serving thereof is triangular in  shape.
    (d) Colored oleomargarine or colored margarine when served
 with meals at a public eating place shall at the time of such service
 be exempt from the labeling requirements of section 403 (except (a)
 and 403 (f))1 if it complies with  the requirements of subsection (b)
 of this section.
    (e) For the purpose of this section colored oleomargarine or col-
 ored  margarine  is oleomargarine or  margarine  having a  tint or
 shade containing more  than one and six-tenths degrees of yellow,
 or of yellow and  red collectively, but with an excess of yellow over
 red, measured in terms of Lovibond tintometer scale or its  equiva-
 lent.
     "(2) all substances, mixtures, and compounds which have a consistence similar to that of
   butter and which contain any edible oils or fats other than milk fat if made in imitation
   or semblance of butter."
In repealing section 2301 of the Internal Revenue Code (relating to the tax on oleomargarine)
Public Law 81-^59 declared, in part: The Congress hereby finds  and declares that the sale,
or the serving in public eating places, of colored oleomargarine or colored margarine without
clear identification as such or which is otherwise adulterated or misbranded within the meaning
of the Federal Food, Drug, and Cosmetic Act depresses the market in interstate commerce for
butter and for oleomargarine or margarine clearly identified and neither adulterated nor mis-
branded, and constitutes a burden on interstate commerce in such articles. Such burden exists,
irrespective of whether such oleomargarine or margarine originates from an interstate source
or from the State in which it is sold."
 Sec. 6 of Public Law 81-459 states that "nothing in this Act shall be construed as authorizing
the possession, sale, or serving of colored oleomargarine or colored margarine in any State or
Territory in contravention of the laws of such State or Territory."
 1 Probably should be "(except paragraphs (a) and (f))".

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Sec. 408	FEDERAL FOOD, DRUG, AND COSMETIC ACT	154

 TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES

    SEC. 408.  [6a] (a) REQUIREMENT FOR TOLERANCE OR EXEMP-
TION.—
        (1) GENERAL RULE.—Except as provided in paragraph (2)
    or (3), any pesticide  chemical residue in or on  a food shall be
    deemed unsafe for the purpose of section 402(a)(2)(B) unless—
            (A) a tolerance for such  pesticide chemical residue in
        or  on  such  food  is in effect under this section and the
        quantity  of  the residue is within the limits of the toler-
        ance; or
            (B) an exemption from the requirement of a tolerance
        is in effect  under this section for the  pesticide  chemical
        residue.
    For the purposes of this section, the term "food", when used as
    a noun without modification, shall mean a raw agricultural
    commodity or processed food.
        (2) PROCESSED FOOD.—Notwithstanding paragraph (1)—
            (A) if a  tolerance is  in effect under this section for a
        pesticide chemical residue in  or on a raw agricultural com-
        modity, a pesticide chemical  residue that is  present in or
        on a processed food because the food is made from that
        raw agricultural commodity shall not be considered unsafe
        within the meaning of section 402(a)(2)(B) despite the lack
        of a tolerance for the pesticide chemical residue in or  on
        the processed food if the pesticide chemical has been used
        in or on the  raw agricultural commodity in conformity with
        a tolerance  under this section, such residue in or on the
        raw agricultural  commodity has been removed to the ex-
        tent possible in good manufacturing practice, and the con-
        centration of the  pesticide chemical residue in the proc-
        essed food is not greater than the tolerance prescribed for
        the pesticide chemical residue in the raw agricultural com-
        modity; or
            (B) if an exemption for the requirement for a tolerance
        is in effect under this section for a pesticide chemical resi-
        due in or on a raw  agricultural commodity,  a pesticide
        chemical residue that is  present in or on a processed food
        because the food is made from that raw agricultural com-
        modity shall not be considered unsafe within the meaning
        of section 402(a)(2)(B).
        (3)  RESIDUES OF DEGRADATION PRODUCTS.—If a pesticide
    chemical residue is  present  in  or on a food because  it is a
    metabolite or other degradation product of a precursor sub-
    stance that itself is a pesticide chemical or pesticide chemical
    residue, such a  residue shall not be  considered to be unsafe
    within the meaning of section 402(a)(2)(B) despite the lack of
    a tolerance or exemption from the need for a tolerance for such
    residue in or on  such food if—
            (A) the  Administrator has not determined that the
        degradation product is likely to pose any potential health
        risk from dietary exposure that is of a different type than,
        or of a greater significance than, any risk posed by dietary
        exposure to  the precursor substance;

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155	FEDERAL FOOD, DRUG, AND  COSMETIC  ACT	Sec. 408

            (B) either—
                (i)  a tolerance is in effect under this section for
            residues of the precursor substance in or on the food,
            and the combined level of residues of the degradation
            product and  the precursor substance in or on the food
            is at or below the stoichiometrically equivalent level
            that would be permitted by the tolerance if the residue
            consisted only of the precursor substance rather than
            the  degradation product; or
                (ii) an exemption from the need for a tolerance is
            in effect under this section for residues of the precur-
            sor substance in or on the food; and
            (C) the tolerance or exemption for residues of the pre-
        cursor substance does not state that it applies only to par-
        ticular named substances and does not state that it  does
        not apply to residues of the degradation product.
        (4) EFFECT OF TOLERANCE OR  EXEMPTION.—While a toler-
    ance or exemption from the requirement for a tolerance is in
    effect under this section for a pesticide chemical residue with
    respect to any food, the food  shall  not by reason of bearing or
    containing any amount of such a residue be considered to be
    adulterated within the meaning of section 402(a)(l).
    (b) AUTHORITY AND STANDARD FOR TOLERANCE.—
        (1) AUTHORITY.—The Administrator may issue regulations
    establishing, modifying, or revoking a tolerance for a pesticide
    chemical residue in or on a food—
            (A) in response to a petition filed under subsection (d);
        or
            (B)  on  the Administrator's own initiative under  sub-
        section (e).
    As used in this section, the term "modify"  shall not mean ex-
    panding the  tolerance to cover additional foods.
        (2) STANDARD.—
            (A) GENERAL RULE.—
                (i)  STANDARD.—The  Administrator may establish
            or leave in effect a tolerance for a  pesticide chemical
            residue in or on a food only if the Administrator deter-
            mines that the tolerance  is  safe.  The Administrator
            shall modify  or revoke a tolerance if the Administrator
            determines it is not safe.
                (ii) DETERMINATION  OF SAFETY.—As used in  this
            section, the term "safe", with respect to a tolerance for
            a pesticide chemical residue, means that the Adminis-
            trator has determined that there is a reasonable cer-
            tainty that no harm  will result from aggregate expo-
            sure to  the  pesticide chemical residue, including all
            anticipated dietary exposures and all other exposures
            for which there is reliable information.
                (iii) RULE OF CONSTRUCTION.—With respect to a
            tolerance,  a  pesticide chemical residue meeting the
            standard under clause (i)  is  not an eligible pesticide
            chemical residue for purposes of subparagraph (B).
            (B)  TOLERANCES FOR ELIGIBLE PESTICIDE  CHEMICAL
        RESIDUES.—

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Sec. 408	FEDERAL FOOD, DRUB. AND COSMETIC ACT	156

                (i) DEFINITION.—As used  in  this  subparagraph,
            the term "eligible pesticide chemical residue" means a
            pesticide chemical residue as to which—
                    (I) the Administrator is not able to identify a
                level of exposure to the residue at which the resi-
                due will not cause or contribute to a known or an-
                ticipated harm to human  health (referred to in
                this section as a "nonthreshold effect");
                    (II) the lifetime risk of experiencing the non-
                threshold effect is appropriately assessed by quan-
                titative risk assessment; and
                    (III) with regard to any known or anticipated
                harm to  human health for which  the Adminis-
                trator is able to identify a level at which the resi-
                due will not cause such harm (referred to in this
                section as a "threshold  effect"), the Administrator
                determines that the level of aggregate exposure is
                safe.
                (ii)   DETERMINATION  OF  TOLERANCE.—Notwith-
            standing subparagraph (A)(i), a tolerance for an eligi-
            ble pesticide chemical residue may be left in effect or
            modified under this subparagraph if—
                    (I) at least one of the conditions described in
                clause (iii) is met; and
                    (II) both of the conditions described in clause
                (iv) are met.
                (iii) CONDITIONS REGARDING USE.—For purposes of
            clause (ii), the conditions described in this clause with
            respect to a tolerance for an eligible pesticide chemical
            residue are the following:
                    (I) Use of the pesticide chemical that produces
                the residue protects consumers from adverse  ef-
                fects on health that would pose a  greater risk
                than the dietary risk from the residue.
                    (II) Use of  the  pesticide chemical that pro-
                duces the  residue  is necessary to  avoid a signifi-
                cant disruption in domestic production of an ade-
                quate, wholesome, and economical food supply.
                (iv) CONDITIONS REGARDING RISK.—For purposes of
            clause (ii), the conditions described in this clause with
            respect to a tolerance for an eligible pesticide chemical
            residue are the following:
                    (I) The yearly risk associated with the non-
                threshold  effect from aggregate exposure to  the
                residue does not exceed 10  times  the yearly risk
                that would be allowed under subparagraph (A) for
                such effect.
                    (II) The tolerance is limited so as to ensure
                that  the risk over a lifetime associated with the
                nonthreshold effect from aggregate  exposure  to
                the residue is not  greater than twice the lifetime
                risk  that would be allowed under subparagraph
                (A) for such effect.

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157	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 408

                (v) REVIEW.—Five years  after the date on which
            the Administrator makes a determination  to leave in
            effect or modify a tolerance under this subparagraph,
            and  thereafter as  the Administrator deems  appro-
            priate, the Administrator shall determine, after notice
            and  opportunity  for comment, whether it has been
            demonstrated  to  the Administrator that a condition
            described in clause (iii)(I) or clause (iii)(II) continues to
            exist with respect to the  tolerance and that the yearly
            and  lifetime  risks  from  aggregate exposure to such
            residue continue to comply with the limits specified in
            clause (iv). If the Administrator determines by such
            date that such demonstration has not been made, the
            Administrator shall, not later than 180 days after the
            date of such  determination, issue a regulation under
            subsection (e)(l) to modify or revoke the tolerance.
                (vi) INFANTS AND CHILDREN.—Any tolerance under
            this subparagraph shall meet the requirements of sub-
            paragraph (C).
            (C) EXPOSURE OF INFANTS AND  CHILDREN.—In estab-
        lishing, modifying, leaving in effect,  or revoking a toler-
        ance or exemption for a pesticide chemical residue, the Ad-
        ministrator—
                (i) shall assess the risk of the pesticide chemical
            residue based on—
                    (I)  available information about consumption
                patterns among infants and children that are like-
                ly to result in disproportionately high consump-
                tion of foods containing  or  bearing  such residue
                among infants  and children in comparison to the
                general population;
                    (II) available information concerning the spe-
                cial susceptibility  of infants and children to the
                pesticide  chemical residues, including neurological
                differences between  infants  and  children  and
                adults, and  effects of in utero exposure to pes-
                ticide chemicals; and
                    (III) available information concerning the cu-
                mulative  effects on infants  and children  of such
                residues  and other substances that have a com-
                mon mechanism of toxicity; and
                (ii) shall—
                    (I)  ensure that there is a reasonable certainty
                that no harm will result to  infants and children
                from aggregate exposure to the pesticide chemical
                residue; and
                    (II) publish a specific determination regarding
                the safety of the pesticide chemical residue for in-
                fants and children.
        The Secretary of Health and  Human Services and the Sec-
        retary of Agriculture, in consultation with  the Adminis-
        trator, shall conduct surveys  to document dietary exposure
        to pesticides among infants  and children. In the case of
        threshold effects, for purposes of clause (ii)(I) an additional

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Sec. 408	FEDERAL FOOD, DRU6, AND COSMETIC ACT	158

        tenfold margin of safety for the pesticide chemical residue
        and other sources  of exposure shall be applied for infants
        and children to take into account potential pre- and post-
        natal toxicity and completeness of the data with respect to
        exposure and toxicity to infants and  children.  Notwith-
        standing such requirement  for  an additional margin of
        safety, the Administrator may use a  different margin of
        safety for the pesticide chemical residue only if,  on the
        basis of reliable data, such margin will be safe for infants
        and children.
            (D)  FACTORS.—In  establishing, modifying, leaving in
        effect, or revoking a tolerance or exemption for a pesticide
        chemical residue, the Administrator shall consider, among
        other relevant factors—
                (i) the validity, completeness, and reliability of the
            available data  from studies  of the pesticide chemical
            and pesticide chemical residue;
                (ii)  the  nature of any toxic  effect shown  to be
            caused by the  pesticide  chemical or pesticide chemical
            residue in such studies;
                (iii) available information concerning the relation-
            ship of the results of such studies to human risk;
                (iv)  available information  concerning the dietary
            consumption patterns of consumers (and major identi-
            fiable subgroups of consumers);
                (v)  available information  concerning the  cumu-
            lative effects of such residues  and other substances
            that have a common mechanism of toxicity;
                (vi)  available  information concerning the  aggre-
            gate exposure  levels of consumers (and major identifi-
            able subgroups of consumers) to the pesticide chemical
            residue and to other related substances, including die-
            tary exposure  under the tolerance and  all other toler-
            ances in effect for the pesticide chemical residue, and
            exposure from other non-occupational sources;
                (vii)  available  information  concerning the  varia-
            bility  of the sensitivities  of major  identifiable sub-
            groups of consumers;
                (viii) such  information as the Administrator may
            require  on whether the  pesticide  chemical may have
            an effect in humans that is similar to an effect pro-
            duced by a naturally occurring estrogen or other endo-
            crine effects; and
                (ix)  safety factors which in the opinion of experts
            qualified by scientific training and experience to evalu-
            ate  the  safety of food additives are generally  recog-
            nized as appropriate for the  use of animal experimen-
            tation data.
            (E)  DATA AND INFORMATION REGARDING  ANTICIPATED
        AND ACTUAL RESIDUE LEVELS.—
                (i) AUTHORITY.—In  establishing, modifying, leav-
            ing  in effect,  or revoking  a tolerance  for a pesticide
            chemical residue,  the  Administrator  may consider
            available data and information on  the anticipated resi-

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159	FEDERAL FOOD, DRUG, AND COSMETIC ACT	Sec. 408

            due levels of the pesticide chemical in or on food and
            the actual residue levels of the pesticide chemical that
            have been measured in food, including residue data
            collected by the Food and Drug Administration.
                (ii) REQUIREMENT.—If the Administrator relies on
            anticipated or  actual  residue levels in establishing,
            modifying, or leaving in effect a tolerance, the Admin-
            istrator shall pursuant to subsection (f)(l) require that
            data be provided five years after the date on which the
            tolerance is established, modified, or left in effect, and
            thereafter as  the  Administrator deems  appropriate,
            demonstrating that such residue levels are not above
            the levels so relied on.  If such data are not  so pro-
            vided, or if the data do not demonstrate that the resi-
            due levels are  not above the levels so relied on, the
            Administrator shall, not later than  180 days after the
            date on which the data were required to be provided,
            issue a regulation under subsection (e)(l), or an order
            under subsection (f)(2), as appropriate, to modify or re-
            voke the tolerance.
            (F) PERCENT OF FOOD ACTUALLY TREATED.—In estab-
        lishing, modifying,  leaving in effect, or  revoking a toler-
        ance for a pesticide chemical residue,  the  Administrator
        may, when assessing chronic dietary risk, consider avail-
        able data and information on the percent of food actually
        treated with the pesticide chemical (including aggregate
        pesticide use data  collected by the Department of  Agri-
        culture) only if the Administrator—
                (i) finds that the data are reliable  and provide a
            valid basis to show what percentage of the food de-
            rived from such crop is likely to contain such pesticide
            chemical residue;
                (ii) finds that the exposure estimate does not un-
            derstate  exposure for any  significant  subpopulation
            group;
                (iii) finds that, if data are available on pesticide
            use and consumption of food in a particular area, the
            population in such area is not dietarily exposed to res-
            idues above those estimated by the Administrator; and
                (iv) provides for the periodic reevaluation of the
            estimate of anticipated dietary exposure.
        (3) DETECTION METHODS.—
            (A) GENERAL RULE.—A tolerance for a pesticide chemi-
        cal residue in or on  a food shall not be established or modi-
        fied by the Administrator unless  the Administrator deter-
        mines, after consultation with the Secretary, that there is
        a practical method for detecting and measuring the levels
        of the pesticide chemical residue in or on the food
            (B) DETECTION  LIMIT.—A tolerance  for  a  pesticide
        chemical residue in or on a  food shall not be established
        at or modified to a level lower than the limit of detection
        of the  method for detecting  and measuring the  pesticide
        chemical residue specified by the Administrator under sub-
        paragraph (A).

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Sec. 408	FEDERAL FOOD, DRUB, AND COSMETIC ACT	160

        (4) INTERNATIONAL  STANDARDS.—In establishing  a toler-
    ance for a pesticide chemical residue in or on a food, the Ad-
    ministrator shall determine whether a maximum residue level
    for the pesticide chemical has been established by the Codex
    Alimentarius Commission. If a Codex maximum residue level
    has been established for the pesticide chemical and the Admin-
    istrator does not propose to adopt the Codex level, the Admin-
    istrator shall publish  for public  comment a notice explaining
    the reasons for departing from the Codex level.
    (c) AUTHORITY AND STANDARD FOR EXEMPTIONS.—
        (1) AUTHORITY.—The Administrator may issue a regulation
    establishing, modifying, or revoking an exemption from the re-
    quirement for a tolerance for a pesticide chemical residue in or
    on food—
           (A) in response to a petition filed under subsection (d);
        or
           (B) on the Administrator's initiative under subsection
        (e).
        (2) STANDARD.—
           (A) GENERAL RULE.—
               (i) STANDARD.—The  Administrator may  establish
           or leave in effect an exemption from the requirement
           for a tolerance for a pesticide chemical residue in or on
           food only if the Administrator determines that the ex-
           emption is safe. The Administrator shall modify or re-
           voke an exemption if the Administrator determines it
           is not safe.
               (ii) DETERMINATION OF SAFETY.—The term "safe",
           with respect to an exemption for a pesticide chemical
           residue, means that the Administrator has determined
           that there is a reasonable certainty that no  harm will
           result from aggregate exposure to the pesticide chemi-
           cal residue, including all anticipated dietary exposures
           and all other  exposures for which there is reliable in-
           formation.
           (B) FACTORS.—In making a determination under this
        paragraph,  the Administrator  shall  take into account,
        among other relevant considerations, the  considerations
        set forth in subparagraphs (C) and (D) of subsection (b)(2).
        (3) LIMITATION.—An exemption from the requirement for a
    tolerance for a pesticide chemical residue in or on  food  shall
    not be established or modified by the Administrator unless the
    Administrator  determines,  after  consultation with  the Sec-
    retary—
           (A) that there is a practical method for detecting and
        measuring the levels of such pesticide chemical residue in
        or on food; or
           (B) that there  is no need for such a method, and states
        the reasons for such determination in issuing the regula-
        tion establishing or modifying the exemption.
    (d) PETITION FOR TOLERANCE OR EXEMPTION.—
        (1) PETITIONS AND PETITIONERS.—Any person may file with
    the Administrator a petition proposing the issuance  of a regu-
    lation—

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161 _ FEDERAL FOOD, DRUG, AND COSMETIC ACT _ Sec. 408

            (A) establishing, modifying, or revoking a tolerance for
        a pesticide chemical residue in or on a food; or
            (B) establishing,  modifying,  or revoking an exemption
        from the requirement of a tolerance for such a residue.
        (2) PETITION CONTENTS. —
            (A) ESTABLISHMENT. — A petition under paragraph (1)
        to establish a tolerance or exemption for a pesticide chemi-
        cal residue shall be supported by such data  and informa-
        tion as are specified in regulations issued by  the Adminis-
        trator, including —
               (i)(I) an informative summary of the petition and
            of the data, information, and arguments  submitted or
            cited in support of the petition; and
               (II)  a statement that the petitioner agrees that
            such summary or any information it contains may be
            published as a part of the notice of filing of the peti-
            tion to be published under this subsection and as part
            of a proposed or final regulation issued under this sec-
            tion;
               (ii) the name, chemical  identity, and composition
            of the pesticide chemical residue and of the  pesticide
            chemical that produces the residue;
               (iii) data showing the recommended  amount, fre-
            quency,  method,  and time of application of that pes-
            ticide chemical;
               (iv)  full  reports of tests and investigations  made
            with respect to the safety of the pesticide chemical, in-
            cluding  full  information  as  to the methods and con-
            trols used in conducting those tests and investigations;
               (v) full reports  of tests and  investigations  made
            with respect to the nature and amount of the pesticide
            chemical residue that is likely to remain in or on the
            food, including a description of the analytical methods
            used;
               (vi)  a practical method for detecting  and measur-
            ing the levels of the  pesticide chemical residue in or on
            the food, or  for exemptions, a statement why such a
            method is not needed;
               (vii) a proposed tolerance for the pesticide chemi-
            cal residue, if a tolerance is proposed;
               (viii) if the petition  relates to a tolerance  for a
            processed  food, reports  of  investigations conducted
            using the processing method(s) used to  produce that
            food;
               (ix)  such information as the  Administrator may
            require to make the determination under subsection
               (x) such information as the Administrator may re-
           quire on whether the pesticide chemical may have an
           effect in humans that is similar to an effect produced
           by a  naturally occurring estrogen or other endocrine
           effects;

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Sec. 408	FEDERAL FOOD, DRUG, AND COSMETIC ACT	162

                (xi) information regarding exposure  to  the  pes-
            ticide chemical residue due to any tolerance or exemp-
            tion already granted for such residue;
                (xii) practical methods for  removing any amount
            of the  residue that would exceed any  proposed toler-
            ance; and
                (xiii) such other data and information as the Ad-
            ministrator requires by regulation to support the peti-
            tion.
        If information or data  required by this subparagraph is
        available to the Administrator, the person submitting the
        petition may cite the availability of the information or data
        in lieu of submitting it. The Administrator may require a
        petition to be accompanied by samples of the  pesticide
        chemical with respect to which the petition  is filed.
            (B)  MODIFICATION  OR  REVOCATION.—The Adminis-
        trator may by regulation establish the requirements for in-
        formation and data to  support a petition to modify or re-
        voke a tolerance or to modify or revoke an  exemption from
        the  requirement for a tolerance.
        (3)  NOTICE.—A notice of the filing of a petition that  the
    Administrator determines has  met the requirements of para-
    graph (2) shall be published by the Administrator within  30
    days after such determination. The notice shall announce  the
    availability of a description of the analytical methods  available
    to the Administrator for the detection and measurement of the
    pesticide chemical residue with respect to  which the petition is
    filed or  shall set forth the  petitioner's statement of why such
    a method is not needed. The notice shall include the summary
    required by paragraph (2)(A)(i)(I).
        (4) ACTIONS BY THE ADMINISTRATOR.—
            (A)  IN GENERAL.—The Administrator shall, after giv-
        ing  due consideration to a petition filed under paragraph
        (1)  and any other information available to the  Adminis-
        trator—
                (i) issue a final regulation  (which  may vary from
            that sought by the petition) establishing, modifying, or
            revoking a tolerance for the pesticide chemical residue
            or an exemption of the pesticide chemical residue from
            the requirement of a tolerance  (which  final regulation
            shall be issued without further  notice and without fur-
            ther period for public comment);
                (ii) issue a proposed regulation under subsection
            (e),  and thereafter issue a final regulation under such
            subsection; or
                (iii) issue an order denying  the petition.
            (B) PRIORITIES.—The Administrator shall give priority
        to petitions for the establishment or modification of a toler-
        ance or exemption for a pesticide chemical residue that ap-
        pears to pose a significantly lower risk to human health
        from  dietary exposure  than  pesticide  chemical residues
        that have tolerances in effect for the same  or similar uses.
            (C) EXPEDITED REVIEW OF CERTAIN PETITIONS.—

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163	FEDERAL FOOD, DRUG. AND  COSMETIC ACT	Sec. 408

                (i) DATE CERTAIN FOR  REVIEW.—If a person files a
            complete petition with  the Administrator proposing
            the issuance of a regulation establishing a tolerance or
            exemption for a pesticide  chemical residue that pre-
            sents a  lower risk to human health than a pesticide
            chemical residue for which a tolerance has been left in
            effect or modified under subsection (b)(2)(B), the Ad-
            ministrator  shall complete  action on  such petition
            under this paragraph within 1 year.
                (ii)  REQUIRED DETERMINATIONS.—If the Adminis-
            trator issues a final regulation establishing a tolerance
            or  exemption  for a  safer  pesticide chemical  residue
            under clause  (i),  the Administrator shall,  not later
            than 180 days after the date on which the regulation
            is issued, determine  whether a condition described in
            subclause (I) or (II)  of subsection (b)(2)(B)(iii) contin-
            ues to exist  with respect to a tolerance that has been
            left in effect or modified under subsection (b)(2)(B). If
            such condition does not continue to exist, the Adminis-
            trator shall,  not later than 180 days after the date on
            which the determination under the preceding sentence
            is made, issue a regulation under subsection (e)(l) to
            modify or revoke the tolerance.
    (e) ACTION ON ADMINISTRATOR'S OWN INITIATIVE.—
        (1) GENERAL RULE.—The  Administrator may issue  a regu-
    lation—
            (A)  establishing,  modifying, suspending under  sub-
        section (1X3), or revoking a tolerance for a pesticide chemi-
        cal or a pesticide chemical residue;
            (B)  establishing,  modifying, suspending under  sub-
        section (1)(3), or revoking  an exemption of a pesticide
        chemical residue from the requirement of a tolerance; or
            (C) establishing general procedures and requirements
        to implement this section.
        (2) NOTICE.—Before issuing  a final regulation under para-
    graph (1), the Administrator shall issue a notice of proposed
    rulemaking and  provide a period of not less than 60 days for
    public  comment on  the  proposed regulation, except  that a
    shorter period for comment  may be provided if the Adminis-
    trator for good cause finds that it would be in the public inter-
    est to do so and states the reasons  for the  finding in the notice
    of proposed rulemaking.
    (f) SPECIAL DATA REQUIREMENTS.—
        (1) REQUIRING SUBMISSION  OF ADDITIONAL  DATA.—If the
    Administrator determines  that additional  data or information
    are reasonably required to support the  continuation of a toler-
    ance or exemption that is in effect under this section for a pes-
    ticide chemical residue on a food, the Administrator shall—
            (A) issue a notice requiring the person holding the pes-
        ticide registrations associated  with such tolerance  or ex-
        emption to submit the data or information  under section
        3(c)(2)(B) of the  Federal  Insecticide,  Fungicide,  and
        Rodenticide Act;

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Sec. 408	FEDERAL FOOD, DRUB. AND COSMETIC ACT	164

            (B) issue a rule requiring that testing be conducted on
        a substance or mixture under section 4 of the Toxic Sub-
        stances Control Act; or
            (C) publish in the Federal Register, after first provid-
        ing notice and an opportunity for comment of not less than
        60 days' duration, an order—
                (i) requiring the submission to the Administrator
            by one or more interested persons of a notice identify-
            ing the person or persons who will submit the required
            data and information;
                (ii) describing the type of data and information re-
            quired to be submitted to the Administrator and stat-
            ing why the data and information could not be ob-
            tained under the authority of section 3(c)(2)(B)  of the
            Federal Insecticide, Fungicide, and  Rodenticide Act or
            section 4 of the Toxic Substances Control Act;
                (iii) describing the reports of the Administrator re-
            quired to be prepared during and after the collection
            of the data and information;
                (iv) requiring the submission to the Administrator
            of the data,  information, and reports  referred to in
            clauses (ii) and (iii); and
                (v) establishing  dates by which  the submissions
            described in clauses (i) and (iv) must be made.
        The Administrator may under subparagraph (C) revise any
        such  order  to correct an  error. The Administrator may
        under this paragraph require data or information pertain-
        ing to whether the pesticide chemical may have an effect
        in humans that is similar to an  effect produced by a natu-
        rally occurring estrogen or other endocrine effects.
        (2) NONCOMPLIANCE.—If a submission required by a notice
    issued in accordance  with paragraph (1)(A),  a rule issued
    under paragraph (1)(B), or an order issued under paragraph
    (1)(C) is not made by the time specified in such notice, rule, or
    order, the Administrator may by order published in the Fed-
    eral Register modify or revoke  the  tolerance or exemption in
    question.  In any review of such an  order under  subsection
    (g)(2), the only material issue shall be whether a submission
    required under paragraph (1) was not made by  the time speci-
    fied.
    (g) EFFECTIVE DATE, OBJECTIONS, HEARINGS, AND ADMINISTRA-
TIVE REVIEW.—
        (1) EFFECTIVE DATE.—A regulation or order issued under
    subsection (d)(4), (e)(l), or (f)(2) shall take effect upon publica-
    tion unless the regulation or order specifies  otherwise. The Ad-
    ministrator may stay the effectiveness of the regulation or
    order if, after issuance of such regulation or order, objections
    are filed with respect to such regulation  or order pursuant to
    paragraph (2).
        (2) FURTHER PROCEEDINGS.—
            (A) OBJECTIONS.—Within 60 days after a regulation or
        order is issued under  subsection (d)(4), (e)(l)(A), (e)(l)(B),
        (f)(2), (n)(3), or  (n)(5)(C), any person may file objections
        thereto with the Administrator,  specifying with particular-

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165	FEDERAL FOOD, DRU6, AND COSMETIC ACT	Sec. 408

        ity the provisions of the regulation or order deemed objec-
        tionable and stating reasonable grounds therefor. If the
        regulation or order was  issued in response to a  petition
        under subsection (d)(l), a copy of each objection filed  by a
        person other than the petitioner shall be served by the Ad-
        ministrator on the petitioner.
            (B) HEARING.—An  objection may include a request for
        a public evidentiary hearing upon the objection. The Ad-
        ministrator shall, upon the initiative of the Administrator
        or upon the request of an interested person and after due
        notice, hold a public evidentiary hearing if and to the ex-
        tent the Administrator  determines that such a public hear-
        ing  is necessary to receive factual evidence relevant to ma-
        terial issues of fact raised by the objections. The presiding
        officer in such a hearing may authorize a party to obtain
        discovery from other persons and may upon a showing of
        good cause made by a party issue  a subpoena to compel
        testimony or production  of documents from  any person.
        The  presiding officer shall be governed by  the  Federal
        Rules of Civil Procedure  in making any order for the pro-
        tection of the witness  or the content of documents  pro-
        duced and shall  order the payment  of reasonable fees and
        expenses as a  condition to requiring testimony of the wit-
        ness.  On contest, such a subpoena  may be enforced  by a
        Federal district court.
            (C) FINAL  DECISION.—As soon as practicable after re-
        ceiving the  arguments of the parties, the Administrator
        shall  issue an order stating the  action taken upon  each
        such objection and setting forth any revision to the regula-
        tion or prior order that the Administrator has found to be
        warranted. If a hearing was held under subparagraph (B),
        such order and  any revision to  the regulation or prior
        order shall, with respect to questions of fact at issue in the
        hearing, be based only  on substantial evidence of record at
        such hearing, and  shall set forth in detail the findings of
        facts and the conclusions of law or  policy upon which the
        order or regulation is based.
    (h) JUDICIAL REVIEW.—
        (1) PETITION.—In a case of actual controversy as to the va-
    lidity  of any regulation issued under subsection (e)(l)(C),  or
    any order issued under subsection (f)(l)(C) or (g)(2)(C), or any
    regulation that is the subject  of such an order, any person who
    will be adversely affected by  such order or regulation may ob-
    tain judicial review by filing in the United States Court of Ap-
    peals  for  the circuit wherein that person resides or has its
    principal place  of business, or in the United States  Court of
    Appeals  for the District of Columbia Circuit, within 60  days
    after publication of such order or regulation, a petition praying
    that the  order or regulation be set aside in whole or in part.
        (2)  RECORD AND JURISDICTION.—A  copy of the petition
    under paragraph (1) shall be forthwith transmitted by the
    clerk  of the court to the  Administrator, or  any officer  des-
    ignated by the Administrator for that purpose, and thereupon
    the Administrator shall file in the court the record of the pro-

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Sec. 408	FEDERAL FOOD, DRUB, AND COSMETIC ACT	166

    ceedings on which the Administrator based the order or regula-
    tion, as provided in section 2112  of title 28, United States
    Code. Upon the filing of such a petition, the court shall have
    exclusive jurisdiction to affirm or set aside the order or regula-
    tion complained of in whole or in part. As to orders issued fol-
    lowing a public evidentiary hearing, the findings of the Admin-
    istrator with respect  to questions  of fact shall be sustained
    only if supported by substantial evidence when considered on
    the record as a whole.
        (3) ADDITIONAL  EVIDENCE.—If a party applies to the  court
    for leave to adduce additional evidence and shows to the  satis-
    faction of the court that the additional evidence is material and
    that there were  reasonable grounds for the failure to adduce
    the evidence in the proceeding before the Administrator, the
    court may order that the additional evidence (and evidence in
    rebuttal thereof) shall be taken before  the Administrator in the
    manner and upon the terms and conditions the  court deems
    proper. The Administrator may modify prior findings as to the
    facts by reason of the additional evidence so taken and may
    modify the order or regulation accordingly. The Administrator
    shall file with the court any such  modified finding, order, or
    regulation.
        (4) FINAL  JUDGMENT; SUPREME  COURT REVIEW.—The judg-
    ment of the court affirming or setting  aside, in whole  or in
    part, any regulation or any order and any regulation  which is
    the subject of such an order shall be final, subject to review by
    the Supreme Court  of the United States as provided in section
    1254 of title 28 of the United States Code. The commencement
    of proceedings under this  subsection shall not, unless specifi-
    cally ordered by the court  to  the contrary, operate as a stay of
    a regulation or order.
        (5) APPLICATION.—Any issue as to which review is or was
    obtainable under this subsection shall not be the subject of ju-
    dicial review under any other provision of law.
    (i) CONFIDENTIALITY AND USE OF DATA.—
        (1)  GENERAL RULE.—Data and information  that are or
    have been submitted to the Administrator under this section or
    section 409 in support of a tolerance  or an  exemption from a
    tolerance shall be entitled to confidential treatment for reasons
    of business confidentiality and to exclusive use and data com-
    pensation to the same extent provided by sections 3 and 10 of
    the Federal Insecticide, Fungicide, and Rodenticide Act.
        (2) EXCEPTIONS.—
            (A) IN GENERAL.—Data and information that  are enti-
        tled to confidential treatment under paragraph (1) may be
        disclosed,  under such security requirements as the Admin-
        istrator may provide by regulation, to—
                (i) employees of the United States authorized by
            the Administrator to examine such  data and  informa-
            tion in the carrying out of their official  duties under
            this Act or other Federal statutes intended to protect
            the public health; or
                (ii) contractors with the United States authorized
            by the Administrator to examine such data and infor-

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167	FEDERAL FOOD. DRUE. AND  COSMETIC ACT	Sec. 408

            mation in the carrying out of contracts under this Act
            or such statutes.
            (B) CONGRESS.—This subsection does not authorize the
        withholding of data or information from either House of
        Congress or from, to the extent of matter within its juris-
        diction, any committee or subcommittee of such committee
        or any joint committee of Congress or any subcommittee of
        such joint committee.
        (3)  SUMMARIES.—Notwithstanding any provision  of this
    subsection or other law, the Administrator may publish the in-
    formative summary  required  by  subsection (d)(2)(A)(i)  and
    may, in issuing a proposed or final regulation  or order under
    this section, publish an informative summary of the data relat-
    ing to the regulation or order.
    (j) STATUS OF PREVIOUSLY ISSUED REGULATIONS.—
        (1) REGULATIONS UNDER  SECTION 406.—Regulations affect-
    ing pesticide chemical residues in  or on raw agricultural com-
    modities promulgated, in accordance with section 701(e), under
    the authority of section 406(a) upon the basis  of public hear-
    ings instituted before January  1, 1953, shall be deemed to be
    regulations issued under  this section and shall be  subject to
    modification  or revocation under subsections (d) and (e), and
    shall be subject to review under subsection (q).
        (2) REGULATIONS UNDER SECTION 409.—Regulations that es-
    tablished tolerances for substances that are pesticide chemical
    residues in or on processed food, or that  otherwise stated the
    conditions under which such  pesticide chemicals could be safe-
    ly used,  and that were issued under  section 409 on or before
    the date of the enactment of this  paragraph, shall  be deemed
    to be regulations issued under this section and shall be subject
    to modification or revocation under subsection (d)  or (e), and
    shall be subject to review under subsection (q).
        (3) REGULATIONS UNDER SECTION 408.—Regulations that es-
    tablished tolerances or exemptions under this section that were
    issued on or before the date of the enactment of this paragraph
    shall remain in  effect unless modified or revoked under sub-
    section (d) or (e), and shall  be subject to review under sub-
    section (q).
    (k) TRANSITIONAL PROVISION.—If, on the day before  the date of
the enactment of this subsection, a substance that is  a pesticide
chemical was, with respect to a particular pesticidal use of the sub-
stance and any resulting pesticide chemical residue in or on a par-
ticular food—
        (1) regarded by the Administrator or the Secretary as gen-
    erally recognized as safe for use within the meaning of the pro-
    visions of subsection (a) or section 201(s) as then in effect; or
        (2) regarded by the Secretary  as a substance described by
    section 201(s)(4);
such a pesticide chemical residue  shall be regarded as exempt from
the requirement for a tolerance, as of the date of enactment of this
subsection. The  Administrator shall by regulation  indicate which
substances are described by this  subsection. Any exemption under
this subsection may be modified or revoked as if it had been issued
under subsection (c).

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Sec. 408	FEDERAL FOOD, DRUE, AND  COSMETIC  ACT	168

    (1) HARMONIZATION WITH ACTION UNDER OTHER LAWS.—
        (1) COORDINATION WITH PIFRA.—To the extent practicable
    and consistent with the review deadlines in subsection (q), in
    issuing a final rule under this subsection that suspends or re-
    vokes a tolerance or exemption for a pesticide chemical residue
    in or  on  food, the Administrator shall coordinate such action
    with any related necessary action under the Federal Insecti-
    cide, Fungicide, and Rodenticide Act.
        (2) REVOCATION OF TOLERANCE OR EXEMPTION FOLLOWING
    CANCELLATION OF ASSOCIATED REGISTRATIONS.—If the Adminis-
    trator, acting under the  Federal  Insecticide, Fungicide,  and
    Rodenticide Act, cancels the registration of each pesticide  that
    contains a particular pesticide chemical and that is labeled for
    use on a particular food,  or requires that the registration of
    each such pesticide be modified to prohibit its use  in connec-
    tion with the production,  storage, or transportation  of such
    food, due in whole or in part to dietary risks to humans posed
    by residues of that pesticide chemical  on that food, the Admin-
    istrator  shall revoke any  tolerance or exemption that allows
    the  presence of the pesticide chemical, or any pesticide chemi-
    cal residue that results from its use,  in or on that food. Sub-
    section (e) shall apply to actions taken under this paragraph.
    A revocation  under this paragraph shall become effective not
    later than 180 days after—
           (A) the date by which each such cancellation of a reg-
        istration has become effective; or
           (B) the date on which the use of the canceled pesticide
        becomes  unlawful  under the terms of the cancellation,
        whichever is later.
        (3) SUSPENSION OF TOLERANCE OR EXEMPTION FOLLOWING
    SUSPENSION OF ASSOCIATED REGISTRATIONS.—
           (A) SUSPENSION.—If the Administrator,  acting under
        the  Federal Insecticide, Fungicide, and Rodenticide  Act,
        suspends the use of each registered pesticide that contains
        a particular pesticide  chemical and that is labeled for use
        on a particular food,  due in whole or in part to dietary
        risks to humans posed by residues of that pesticide chemi-
        cal on that food, the Administrator shall suspend any tol-
        erance or exemption that allows  the presence of the  pes-
        ticide chemical, or any pesticide chemical residue that re-
        sults from its use, in  or on that food. Subsection (e) shall
        apply to actions taken under this  paragraph. A suspension
        under this paragraph  shall become effective not later than
        60 days after the date by which  each  such suspension of
        use has become effective.
            (B) EFFECT OF SUSPENSION.—The suspension of a tol-
        erance or exemption under  subparagraph (A) shall be ef-
        fective as long as the use of each  associated registration of
        a pesticide  is suspended under  the  Federal Insecticide,
        Fungicide,  and Rodenticide  Act. While a  suspension  of a
        tolerance or exemption is effective the tolerance or exemp-
        tion shall not be considered to be in effect. If the suspen-
        sion  of use of the pesticide  under that Act is terminated,
        leaving the registration of the pesticide for such use in ef-

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169	FEDERAL FOOD. DRUG, AND COSMETIC  ACT	Sec. 408

        feet under that Act, the Administrator shall rescind any
        associated suspension of tolerance or exemption.
        (4) TOLERANCES  FOR UNAVOIDABLE RESIDUES.—In  connec-
    tion with action  taken under paragraph (2) or (3), or with re-
    spect to pesticides whose registrations were suspended or can-
    celed prior to the date of the enactment of this paragraph
    under the Federal Insecticide, Fungicide, and Rodenticide Act,
    if the Administrator determines that a residue of the canceled
    or suspended pesticide chemical will unavoidably persist in the
    environment  and thereby be present in or on a food, the Ad-
    ministrator may establish a tolerance for the pesticide chemi-
    cal residue. In establishing such a tolerance, the Administrator
    shall take into account both the factors set forth in subsection
    (b)(2) and the unavoidability of the residue.  Subsection (e) shall
    apply to the establishment of such tolerance. The  Adminis-
    trator shall review any such tolerance periodically and modify
    it as necessary so that it allows no greater level of the pesticide
    chemical residue than is unavoidable.
        (5) PESTICIDE RESIDUES RESULTING PROM LAWFUL APPLICA-
    TION OF PESTICIDE.—Notwithstanding any other provision  of
    this Act, if a tolerance or exemption  for a pesticide chemical
    residue in or on  a food has been revoked, suspended, or modi-
    fied under this  section, an article  of that food shall not be
    deemed unsafe solely because of the presence of such pesticide
    chemical residue in or on such food if it is  shown to  the satis-
    faction of the Secretary that—
            (A) the residue is present as the result of an applica-
        tion or use of a pesticide at a time and in a manner  that
        was lawful under the Federal Insecticide, Fungicide, and
        Rodenticide Act; and
            (B) the residue does not exceed a  level that was au-
        thorized  at  the  time of  that  application  or use to be
        present on the food under a tolerance, exemption, food ad-
        ditive  regulation, or other sanction then in  effect under
        this Act;
    unless, in the case of any tolerance or exemption revoked,  sus-
    pended,  or modified under this subsection or subsection (d) or
    (e),  the  Administrator has issued a determination  that  con-
    sumption of the  legally treated food during the period of its
    likely availability in commerce will  pose an unreasonable die-
    tary risk.
       (6) TOLERANCE FOR USE  OF  PESTICIDES UNDER AN EMER-
    GENCY EXEMPTION.—If the Administrator grants an exemption
    under section 18 of the Federal Insecticide, Fungicide,  and
    Rodenticide Act (7 U.S.C. 136p) for a pesticide chemical, the
    Administrator shall establish  a tolerance or exemption  from
    the requirement for a tolerance for the pesticide chemical resi-
    due. Such a tolerance or exemption from a tolerance shall have
    an expiration date.  The Administrator may establish  such a
    tolerance or exemption without providing notice or a period for
    comment on  the  tolerance  or exemption. The  Administrator
    shall promulgate regulations within  365 days after the date of
    the enactment of this paragraph governing the establishment
    of tolerances and exemptions under this paragraph. Such regu-

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Sec. 408	FEDERAL FOOD,  DRUB, AND COSMETIC ACT	170

    lations shall be consistent with the safety standard under sub-
    sections (b)(2) and (c)(2) and with section 18 of the Federal In-
    secticide, Fungicide, and Rodenticide Act.
    (m) FEES.—
        (1) AMOUNT.—The Administrator shall by regulation re-
    quire the payment of such fees as will in the aggregate, in the
    judgment of the Administrator, be sufficient over a reasonable
    term to provide, equip, and maintain an adequate service for
    the performance of the  Administrator's functions  under this
    section. Under the regulations, the performance of the Admin-
    istrator's services or other functions under this section, includ-
    ing—
            (A) the acceptance  for filing of a petition  submitted
        under subsection (d);
            (B) establishing, modifying, leaving in effect, or revok-
        ing a tolerance or establishing,  modifying, leaving in effect,
        or revoking an exemption from  the requirement for a toler-
        ance under this section;
            (C) the acceptance for filing of objections  under sub-
        section (g); or
            (D) the certification and  filing in court of a transcript
        of the proceedings and the record under subsection (h);
    may be conditioned upon the payment of such fees. The regula-
    tions may further provide for waiver or refund of fees in whole
    or in part when in the judgment of the Administrator such a
    waiver or refund is equitable and not contrary to the purposes
    of this subsection.
        (2) DEPOSIT.—All fees collected under paragraph (1)  shall
    be deposited in the  Reregistration and Expedited Processing
    Fund created by section 4(k) of the Federal  Insecticide,  Fun-
    gicide, and Rodenticide Act.  Such fees shall be available to the
    Administrator, without fiscal year  limitation, for the perform-
    ance of the Administrator's services or functions as specified in
    paragraph (1).
    (n) NATIONAL UNIFORMITY OF TOLERANCES.—
        (1) QUALIFYING  PESTICIDE CHEMICA^ RESIDUE.—For pur-
    poses of this subsection, the term "qualifying pesticide chemi-
    cal residue" means a pesticide chemical residue resulting from
    the use, in production, processing, or storage of a food, of a pes-
    ticide chemical that is an active ingredient and that-y-
            (A) was first approved for such use in a registration of
        a pesticide issued under section 3(c)(5) of the Federal In-
        secticide, Fungicide, and Rodenticide Act on or after April
        25, 1985, on the basis of data determined by the Adminis-
        trator  to meet all  applicable requirements for data pre-
        scribed by regulations in effect under that Act on April 25,
        1985; or
            (B) was approved for such use in a reregistration eligi-
        bility determination issued under section 4(g) of that Act
        on or after the date of enactment of this subsection.
        (2) QUALIFYING FEDERAL DETERMINATION.—For purposes of
    this subsection, the term "qualifying Federal  determination"
    means a tolerance or exemption from the requirement for a tol-
    erance for a qualifying pesticide chemical residue that—

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171	FEDERAL FOOD,  DRUS, AND COSMETIC ACT	Sec. 408

            (A) is issued under this section after the date of the
        enactment  of this subsection and determined by  the Ad-
        ministrator to  meet  the   standard  under  subsection
        (b)(2)(A) (in the  case of a tolerance) or (c)(2) (in the case
        of an exemption); or
            (B)(i) pursuant to subsection (j) is remaining in effect
        or is deemed to have been issued under this section, or is
        regarded under subsection (k) as exempt from the  require-
        ment for a tolerance; and
            (ii) is determined  by the Administrator to meet  the
        standard under subsection (b)(2)(A) (in the case of a toler-
        ance) or (c)(2) (in the case of an exemption).
        (3) LIMITATION.—The Administrator may  make the  deter-
    mination described in paragraph (2)(B)(ii)  only by issuing  a
    rule in accordance with  the procedure  set forth in subsection
    (d) or (e) and only if the Administrator issues a proposed rule
    and allows a period  of not less  than 30 days for comment on
    the proposed rule. Any such rule shall be reviewable in accord-
    ance with subsections (g) and (h).
        (4) STATE AUTHORITY.—Except  as provided  in paragraphs
    (5), (6), and (8) no State  or political subdivision may establish
    or enforce any regulatory limit on a qualifying pesticide chemi-
    cal residue in or on any food if a qualifying Federal determina-
    tion applies  to the presence of such pesticide chemical residue
    in or on such food, unless such  State regulatory limit is iden-
    tical to such qualifying Federal determination. A State  or polit-
    ical subdivision shall be deemed to establish or enforce a regu-
    latory limit on  a pesticide  chemical residue in or on a food  if
    it purports to prohibit or penalize  the  production,  processing,
    shipping, or other handling of a food because it contains a pes-
    ticide  residue (in excess of a prescribed limit).
        (5) PETITION PROCEDURE.—
            (A) IN GENERAL.—Any State may petition the Adminis-
        trator for authorization to establish in such State a regu-
        latory limit on a qualifying pesticide chemical residue in or
        on any food that is not identical to the qualifying Federal
        determination  applicable  to  such  qualifying pesticide
        chemical residue.
            (B) PETITION REQUIREMENTS.—Any petition under sub-
        paragraph (A) shall—
                (i)  satisfy any requirements prescribed, by rule, by
            the Administrator; and
                (ii) be supported by scientific data  about the pes-
            ticide chemical residue that is  the subject of the peti-
            tion or about chemically related pesticide chemical res-
            idues, data on the consumption within such State of
            food bearing the pesticide chemical residue, and data
            on exposure of humans within  such State to the pes-
            ticide chemical residue.
            (C)  AUTHORIZATION.—The  Administrator  may,  by
        order, grant the authorization  described in subparagraph
        (A)  if the  Administrator determines that  the proposed
        State regulatory limit—
                (i)  is justified by compelling local conditions; and

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Sec. 408	FEDERAL FOOD,  DRUG. AND COSMETIC ACT	172

                (ii) would not cause  any food to be a violation of
            Federal law.
            (D) TREATMENT.—In lieu  of any  action  authorized
        under  subparagraph (C), the Administrator may treat  a
        petition under  this  paragraph as  a petition under sub-
        section (d) to modify or  revoke a tolerance or an exemp-
        tion. If the Administrator determines to treat a petition
        under  this paragraph as a petition under subsection (d),
        the Administrator shall thereafter act on the petition pur-
        suant to subsection (d).
            (E) REVIEW.—Any order of the Administrator granting
        or denying the authorization described in subparagraph
        (A) shall be subject to  review in  the manner described in
        subsections (g) and (h).
        (6)  URGENT PETITION PROCEDURE.—Any State petition to
    the  Administrator  pursuant  to paragraph  (5)  that  dem-
    onstrates that consumption of a food  containing such pesticide
    residue level during the  period of the food's likely availability
    in the State will pose a significant public health threat from
    acute exposure shall  be considered an urgent petition.  If an
    order by the Administrator to grant or deny the requested au-
    thorization in an urgent petition is not made  within 30 days
    of receipt of the petition, the petitioning State may  establish
    and enforce a temporary regulatory limit on a qualifying pes-
    ticide chemical residue in or  on the food. The temporary regu-
    latory limit shall be validated or terminated by the  Adminis-
    trator's final order on  the petition.
        (7) RESIDUES FROM LAWFUL, APPLICATION.—No State  or po-
    litical subdivision may enforce any regulatory limit on the level
    of a  pesticide  chemical residue that may appear in or on any
    food  if,  at the time of the application of the pesticide that re-
    sulted in such residue, the sale of such  food with such residue
    level was lawful under this section and under  the law of such
    State, unless the State demonstrates that consumption  of the
    food  containing such  pesticide  residue level during the period
    of the food's likely availability in  the  State will pose an unrea-
    sonable dietary risk to the health of persons within such  State.
        (8)  SAVINGS.—Nothing in this Act preempts the  authority
    of any State or political subdivision to require that a food con-
    taining a pesticide chemical  residue bear or be the subject of
    a warning or  other statement relating  to the  presence  of the
    pesticide chemical residue in  or on such  food.
    (o) CONSUMER RIGHT  To KNOW.—Not later than 2 years after
the date of the enactment of the Food Quality Protection Act of
1996, and annually thereafter, the Administrator shall, in consulta-
tion with the Secretary of Agriculture and the Secretary of Health
and Human Services, publish in  a format understandable to a lay
person, and distribute to  large retail grocers  for public display (in
a manner determined by  the grocer), the following information, at
a minimum:
        (1) A discussion of the risks and benefits of pesticide  chem-
    ical residues in or on food purchased by  consumers.
        (2)  A listing of actions taken under subparagraph  (B) of
    subsection  (b)(2) that  may result in pesticide chemical residues

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173	FEDERAL FOOD, DRUG, AND COSMETIC ACT	Sec. 408

    in or on food that present a yearly or lifetime risk above the
    risk allowed under subparagraph (A) of such subsection, and
    the food on which the pesticide chemicals producing the resi-
    dues are used.
        (3) Recommendations to consumers for reducing dietary ex-
    posure to  pesticide chemical residues in a manner consistent
    with maintaining a healthy diet, including a list of food that
    may reasonably substitute for food listed under paragraph (2).
    Nothing in this subsection shall prevent retail grocers from
providing additional information.
    (p) ESTROGENIC SUBSTANCES SCREENING PROGRAM.—
        (1) DEVELOPMENT.—Not later than 2 years after the date
    of enactment of this  section, the Administrator shall  in con-
    sultation with the Secretary of Health and Human Services de-
    velop  a screening program,  using appropriate validated test
    systems and other scientifically relevant information, to deter-
    mine whether certain substances may have  an effect in hu-
    mans that is similar to an effect produced by a naturally occur-
    ring estrogen, or such other endocrine effect as the Adminis-
    trator may designate.
        (2) IMPLEMENTATION.—Not later  than 3  years  after the
    date of enactment of  this section, after obtaining public com-
    ment and review of the screening program described in para-
    graph (1)  by the scientific  advisory panel established under
    section  25(d)  of  the  Federal Insecticide,   Fungicide,  and
    Rodenticide Act  or  the  science advisory  board established by
    section 8  of the Environmental Research, Development, and
    Demonstration Act of  1978 (42 U.S.C. 4365), the Administrator
    shall implement the program.
        (3) SUBSTANCES.—In carrying out the  screening program
    described in paragraph (1), the Administrator—
           (A) shall provide for the testing of all pesticide chemi-
        cals; and
           (B) may provide for the testing of any other substance
        that may have an effect that is cumulative to  an effect  of
        a pesticide  chemical if the Administrator determines that
        a substantial  population may  be exposed to  such sub-
        stance.
        (4) EXEMPTION.—Notwithstanding  paragraph (3), the Ad-
    ministrator may, by order,  exempt from the requirements  of
    this section a biologic substance or other substance if the Ad-
    ministrator determines that the substance is anticipated not  to
    produce any effect in humans similar to an effect produced by
    a naturally occurring estrogen.
        (5) COLLECTION OF INFORMATION.—
           (A) IN  GENERAL.—The Administrator  shall issue  an
        order to a registrant of a substance for which testing is re-
        quired under this  subsection, or to a person who manufac-
        tures or imports a substance for which testing is required
        under this  subsection,  to  conduct testing in accordance
        with  the screening program described in  paragraph (1),
        and submit information obtained from the testing to the
        Administrator, within a  reasonable time  period that the

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Sec. 408	FEDERAL FOOD, DRUG, AND  COSMETIC ACT	174

        Administrator determines is sufficient for the generation of
        the information.
            (B)  PROCEDURES.—To the extent practicable the Ad-
        ministrator shall minimize duplicative testing of the same
        substance for the same endocrine effect, develop, as appro-
        priate, procedures  for  fair and  equitable sharing of test
        costs, and develop,  as necessary, procedures for handling of
        confidential business information.
            (C)  FAILURE  OF  REGISTRANTS  TO SUBMIT  INFORMA-
        TION.—
                (i) SUSPENSION.—If a registrant of a substance re-
            ferred to in paragraph (3)(A) fails to comply with an
            order under subparagraph (A) of this paragraph, the
            Administrator  shall issue a notice of intent to suspend
            the  sale or distribution of the  substance by the reg-
            istrant.  Any  suspension  proposed under this  para-
            graph shall become final at  the end of the 30-day pe-
            riod beginning on the date that the registrant receives
            the  notice of intent to suspend, unless during that pe-
            riod a person adversely affected by the notice requests
            a hearing or the Administrator determines  that the
            registrant has  complied fully with this paragraph.
                (ii)  HEARING.—If  a  person  requests  a  hearing
            under clause (i), the hearing shall be conducted in ac-
            cordance with section 554  of title 5,  United States
            Code. The only matter for resolution at the  hearing
            shall be whether the registrant has failed to comply
            with an order under subparagraph  (A) of this para-
            graph. A decision by the  Administrator after comple-
            tion of a hearing shall be  considered  to be a final
            agency action.
                (iii) TERMINATION OF SUSPENSIONS.—The Adminis-
            trator shall  terminate a  suspension under this sub-
            paragraph issued with respect to a registrant if the
            Administrator  determines  that the registrant has com-
            plied fully with this paragraph.
            (D)  NONCOMPLIANCE BY OTHER PERSONS.—Any person
        (other than a registrant) who fails to comply with an order
        under subparagraph (A) shall be liable for  the same pen-
        alties and sanctions as are provided under section 16 of
        the Toxic Substances Control Act (15 U.S.C. 2601 and fol-
        lowing)  in the case of a violation referred to in that sec-
        tion.  Such penalties and sanctions shall be assessed and
        imposed in the same  manner as provided in such section
        16.
        (6) AGENCY ACTION.—In the case of any substance that is
    found, as a  result of testing and evaluation under this section,
    to have  an  endocrine effect on  humans, the  Administrator
    shall, as appropriate, take action under such statutory author-
    ity as is available to the Administrator, including consideration
    under other sections of this Act, as is necessary to ensure the
    protection of public health.

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175	FEDERAL FOOD. DRU6, AND COSMETIC ACT	Sec. 408

        (7) REPORT TO CONGRESS.—Not later than 4 years after the
    date of enactment of this section, the Administrator shall pre-
    pare and submit to Congress a report containing—
            (A)  the findings of the  Administrator resulting from
        the screening program described in paragraph (1);
            (B)  recommendations for further  testing needed  to
        evaluate the impact on human  health of the substances
        tested under the screening program; and
            (C)  recommendations  for any further actions (includ-
        ing any action described in paragraph (6)) that the Admin-
        istrator determines are appropriate based on the findings.
    (q) SCHEDULE FOR REVIEW.—
        (1)  IN  GENERAL.—The  Administrator shall  review toler-
    ances and exemptions for pesticide chemical residues in effect
    on the day before the date of the enactment of the Food Qual-
    ity Protection Act of 1996, as  expeditiously as practicable, as-
    suring that—
            (A)  33  percent of such tolerances and exemptions are
        reviewed within 3  years of the date  of enactment of such
        Act;
            (B)  66  percent of such tolerances and exemptions are
        reviewed within 6  years of the date  of enactment of such
        Act; and
            (C)  100 percent of such tolerances and exemptions are
        reviewed within 10 years of  the date of enactment of such
        Act.
    In conducting a review  of a tolerance  or exemption, the Admin-
    istrator shall determine  whether the tolerance  or exemption
    meets the requirements of subsections (b)(2) or (c)(2) and shall,
    by the deadline for the review of the tolerance or exemption,
    issue a regulation under subsection (d)(4) or (e)(l) to modify or
    revoke the tolerance or exemption if the tolerance or exemption
    does not meet such requirements.
        (2)  PRIORITIES.—In determining  priorities for reviewing
    tolerances and  exemptions under paragraph (1), the Adminis-
    trator shall give priority to the review of the  tolerances or ex-
    emptions that appear to pose the greatest risk to public health.
        (3) PUBLICATION OF SCHEDULE.—Not later than 12 months
    after the date of the enactment of the Food Quality Protection
    Act of 1996, the Administrator shall publish a schedule for re-
    view of tolerances and exemptions established prior to the date
    of the enactment of the Food Quality Protection Act of 1996.
    The determination of priorities for the review of tolerances and
    exemptions pursuant to this subsection  is not a  rulemaking
    and shall not be subject to  judicial review, except that failure
    to take final action pursuant to the schedule established  by
    this paragraph shall be subject to judicial review.
    (r) TEMPORARY TOLERANCE OR EXEMPTION.—The Administrator
may, upon  the request of any person who has obtained an experi-
mental permit for a pesticide chemical under the Federal Insecti-
cide, Fungicide,  and Rodenticide Act or upon the Administrator's
own initiative, establish  a temporary  tolerance or exemption for the
pesticide chemical residue for the uses covered by the permit. Sub-

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Sec. 409	FEDERAL FOOD, DRUG. AND COSMETIC  ACT	176

sections (b)(2), (c)(2), (d), and (e) shall apply to actions taken under
this subsection.
    (s) SAVINGS  CLAUSE.—Nothing in this section  shall be  con-
strued to amend or modify the provisions of the Toxic Substances
Control Act or the Federal Insecticide, Fungicide, and Rodenticide
Act.

                        FOOD ADDITIVES

                     Unsafe Food Additives

    SEC. 409. [348] (a) A food additive shall, with respect to any
particular use or intended use of such additives, be deemed to be
unsafe for the purposes of the application of clause (2)(C) of section
402(a), unless—
        (1) it and its use or intended use conform to the terms of
    an exemption which is in effect pursuant  to subsection (i) of
    this section; or
        (2) there is in effect, and it and its use  or intended use are
    in conformity with, a regulation issued under this section pre-
    scribing the conditions under which such additive may be safe-
    ly used.
While such  a regulation relating  to a food additive is in effect,  a
food shall not, by reason of bearing or containing such an additive
in accordance with the regulation, be considered adulterated within
the meaning of clause (1) of section 402(a).

                   Petition To Establish Safety

    (b)(l) Any person  may, with respect to any intended use of a
food additive, file with the Secretary a petition proposing the issu-
ance  of a regulation prescribing the conditions under which such
additive may be safely used.
    (2) Such petition shall, in  addition to any explanatory or sup-
porting data, contain—
        (A) the  name and all pertinent  information  concerning
    such  food  additive, including, where  available, its  chemical
    identity and composition;
        (B) a statement of the conditions of the  proposed use of
    such  additive, including all directions, recommendations, and
    suggestions proposed for the use of such additive, and includ-
    ing specimens of its proposed labeling;
        (C) all relevant data bearing on the physical or other tech-
    nical effect such additive is intended to produce, and the quan-
    tity of such  additive required to produce such effect;
        (D) a description of practicable methods for determining
    the quantity of such additive  in or on food, and any substance
    formed in or on food, because of its use; and
        (E) full reports of investigations made with respect to the
    safety for use of such additive, including full information as to
    the methods  and  controls used in conducting such investiga-
    tions.
    (3) Upon request of the Secretary, the petitioner shall furnish
(or, if the petitioner is not the manufacturer of such additive, the
petitioner shall have  the manufacturer of such additive furnish,

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177	FEDERAL FOOD, DRUG, AND COSMETIC ACT	Sec. 409

without disclosure to the petitioner), a full description of the meth-
ods used in, and the facilities and controls used for, the production
of such additive.
    (4) Upon request of the Secretary, the petitioner shall furnish
samples  of the  food additive  involved, or articles used as compo-
nents thereof, and of the food in or on which the additive is pro-
posed to be used.
    (5) Notice of the regulation proposed by the petitioner shall be
published  in general terms by  the Secretary within  thirty days
after filing.

                     Action on the Petition

    (c)(l) The Secretary shall—
        (A) by order establish a regulation (whether or not in ac-
    cord with that proposed by the petitioner) prescribing, with re-
    spect to one or more proposed uses of the  food  additive in-
    volved, the conditions under which such additive may be safely
    used (including, but not limited to, specifications as to the par-
    ticular food or classes of food in or on which such additive may
    be used, the maximum quantity  which  may be used or per-
    mitted to remain in or on such food, the manner in which such
    additive may be added to or used in or on such food, and any
    directions or other labeling or packaging requirements for such
    additive deemed necessary by him to assure the safety of such
    use), and shall notify the  petitioner of such order and the rea-
    sons for such action; or
        (B) by order deny the petition, and shall notify  the peti-
    tioner  of such order and of the reasons for such action.
    (2) The order required by paragraph (1) (A) or (B) of this sub-
section shall be issued  within ninety days after  the date of filing
of the petition, except that the Secretary may (prior to such nine-
tieth day),  by written notice to the petitioner, extend such ninety-
day period to such  time (not more than one hundred  and eighty
days after  the date of filing of the petition) as the Secretary deems
necessary to enable him to study and investigate the petition.
    (3) No such regulation shall issue if a fair evaluation of the
data before the Secretary—
        (A) fails to establish that the proposed use of the food addi-
    tive,  under the  conditions of use to be specified  in the regula-
    tion, will be safe: Provided, That no additive shall be deemed
    to be safe if it is found to  induce cancer when ingested by man
    or  animal,  or if it is found,  after tests which are  appropriate
    for the evaluation of the safety of food additives,  to induce can-
    cer in  man or animal, except that this proviso shall not apply
    with respect to the  use of a substance as an ingredient of feed
    for animals which  are  raised for food production,  if the Sec-
    retary  finds (i)  that, under the conditions of use and feeding
    specified in  proposed labeling and reasonably certain to be fol-
    lowed  in practice, such additive will not adversely affect  the
    animals for which such feed is intended, and (ii) that no resi-
    due of the  additive will be found  (by methods of examination
    prescribed or approved by the Secretary by regulations, which
    regulations  shall not be subject to  subsections (f) and (g)) in

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Sec. 409	FEDERAL FOOD, DRUB, AND COSMETIC  ACT	178

    any edible portion of such animal after slaughter or in any food
    yielded by or derived from the living animal; or
        (B) shows that the proposed use of the  additive would pro-
    mote  deception of the  consumer in violation  of  this Act  or
    would otherwise result in adulteration or in misbranding of
    food within the meaning of this Act.
    (4) If, in the judgment of the Secretary, based upon a fair eval-
uation of the data before him, a tolerance limitation is required in
order to assure that the proposed use of an additive will be safe,
the Secretary—
        (A) shall not fix such tolerance limitation at a  level higher
    than  he  finds to be reasonably  required  to accomplish  the
    physical or other technical effect for which  such additive is in-
    tended; and
        (B) shall not establish a regulation for such proposed use
    if he finds upon a fair evaluation of the data before him  that
    such data do not establish that such use would accomplish the
    intended physical or other technical effect.
    (5) In determining, for the purposes of this section, whether a
proposed use of a food additive is safe, the Secretary shall consider
among other relevant factors—
        (A) the  probable  consumption of the additive and of any
    substance formed in or on  food because of the use  of the addi-
    tive;
        (B) the  cumulative effect of such additive  in the diet of
    man or animals, taking into account any chemically or phar-
    macologically related substance or substances in such diet; and
        (C) safety factors which in the opinion  of experts qualified
    by scientific training and experience to evaluate the safety of
    food additives are generally  recognized as  appropriate for the
    use of animal experimentation data.

           Regulation Issued on Secretary's Initiative

    (d)  The Secretary may at any time, upon his  own initiative,
propose the issuance of a regulation  prescribing, with respect to
any particular use of  a food additive, the conditions under which
such  additive  may be  safely used, and the reasons therefor. After
the thirtieth day following publication of such a proposal, the Sec-
retary may by order establish a regulation based  upon the  pro-
posal.

             Publication and Effective Date of Orders

    (e)  Any order,  including any regulation established by such
order, issued  under subsection (c) or (d) of this section, shall  be
published and shall be effective upon publication, but the Secretary
may stay  such effectiveness if, after issuance of such order, a hear-
ing is sought with respect to such order pursuant to subsection (f).

                  Objections and Public Hearing

    (f)(l)  Within thirty days after publication of an  order made
pursuant  to subsection (c)  or  (d) of this section, any person ad-

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179	FEDERAL FOOD, DRUG, AND COSMETIC ACT	Sec. 409

versely affected by such an order may file objections thereto with
the Secretary, specifying with particularity the provisions of the
order deemed  objectionable, stating reasonable grounds  therefor,
and requesting a public hearing upon  such objections. The  Sec-
retary shall, after due notice, as promptly as possible hold such
public hearing for the purpose of receiving evidence  relevant and
material to the issues raised by such objections. As soon as prac-
ticable after completion of the hearing, the Secretary shall by order
act upon such objections and make such order public.
    (2)  Such order shall be based upon a fair evaluation of the en-
tire record at such hearing,  and shall include a statement setting
forth in detail the findings and conclusions upon which the order
is based.
    (3)  The Secretary shall specify in the order the date on which
it shall take effect, except that it shall not be made to take effect
prior to the ninetieth day after its publication, unless the Secretary
finds that emergency conditions exist necessitating an earlier effec-
tive date, in which event the Secretary shall specify in the order
his findings as to such conditions.

                        Judicial Review

    (g)(l) In a case of actual controversy as to the validity of any
order issued under subsection (f), including any order thereunder
with respect to amendment or repeal of a regulation  issued under
this section, any  person who will be adversely affected by such
order may  obtain judicial review by filing in the United  States
Court of Appeals for the circuit wherein such person resides or has
his principal place of business, or in the United States Court of Ap-
peals for the District of Columbia Circuit,  within sixty days after
the entry of such order, a petition  praying that the  order be set
aside in whole or in part.
    (2)  A copy of such petition shall be  forthwith transmitted by
the clerk of the court to the Secretary, or any officer designated by
him for that purpose, and thereupon the Secretary shall file in the
court the record of the proceedings on which he based his  order, as
provided in section 2112 of title 28, United States  Code. Upon  the
filing of such petition the court shall have jurisdiction, which upon
the filing of the record with it shall be  exclusive,  to  affirm or set
aside the  order complained of in whole or in part. Until the filing
of the record the Secretary may modify or set aside his order. The
findings of the Secretary with respect to  questions of fact shall be
sustained if based upon a fair evaluation  of the entire record at
such hearing.
    (3)  The court, on such judicial review, shall not sustain  the
order of the Secretary if he failed to comply with any requirement
imposed on him by subsection (f)(2) of this section.
    (4) If application is made to the court for leave to  adduce addi-
tional evidence, the court may order such additional evidence to be
taken before the Secretary and to be adduced upon the hearing in
such manner and upon such terms  and conditions as to the court
may seem proper, if such evidence is material and there were rea-
sonable grounds for failure to adduce such evidence in the proceed-
ings below.  The Secretary may modify his findings as to the facts

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Sec. 410	FEDERAL FOOD. DRUE, AND  COSMETIC ACT	180

and order by reason of the additional evidence so taken, and shall
file with the court such modified findings and order.
    (5)  The judgment of the court affirming or setting aside,  in
whole or in part, any order under this section shall be final, subject
to review  by the Supreme Court of the United States upon certio-
rari or  certification as provided in section 1254 of title 28 of the
United States Code. The commencement of proceedings under this
section shall not, unless specifically ordered by the court to the con-
trary, operate as a stay of an order.

              Amendment or Repeal of Regulations

    (h)  The Secretary shall by regulation prescribe  the procedure
by which regulations under the foregoing provisions  of this section
may be  amended or repealed, and such procedure shall conform to
the procedure provided in this section for the promulgation of such
regulations.

               Exemptions for Investigational Use

    (i) Without regard to subsections  (b) to  (h), inclusive, of this
section,  the Secretary shall by regulation provide  for exempting
from the requirements of this  section any food additive, and any
food bearing or containing such additive, intended solely for inves-
tigational  use by qualified experts when in his opinion such exemp-
tion is consistent with the public health.

              BOTTLED DRINKING WATER STANDARDS

    SEC. 410. [349] (a) Except as provided in subsection (b), when-
ever the Administrator of the Environmental  Protection Agency
prescribes interim or revised national primary drinking water regu-
lations  under section 1412 of the Public Health Service Act, the
Secretary  shall consult with the Administrator and within 180 days
after the  promulgation  of such drinking water regulations either
promulgate amendments to regulations under this chapter applica-
ble to bottled drinking water or publish in the Federal Register his
reasons  for not making such amendments.
    (b)(l)  Not later than 180 days before the  effective date of a na-
tional primary drinking water  regulation promulgated  by the Ad-
ministrator of the Environmental Protection Agency  for a contami-
nant under section  1412 of the Safe Drinking Water  Act (42 U.S.C.
300g-l), the Secretary shall promulgate a standard of quality regu-
lation under this subsection for that contaminant in bottled water
or make a finding that such a regulation is not necessary to protect
the public health because the contaminant is contained  in water in
public water systems (as defined under section 1401(4)  of such Act
(42 U.S.C. 300fl;4))) but not in  water used for bottled  drinking
water. The effective date for any such  standard of quality regula-
tion shall be the same as the effective date for such national pri-
mary drinking water regulation, except for any standard of quality
of regulation promulgated by the  Secretary before the  date of en-
actment of the Safe Drinking Water Act Amendments  of 1996 for
which (as  of such date of enactment) an effective date had not been
established. In the case of a standard of quality regulation to which
such exception applies, the Secretary shall promulgate monitoring

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181	FEDERAL FOOD,  DRUG, AND COSMETIC ACT	Sec. 411

requirements for the contaminants covered by the regulation not
later than 2 years after such date of enactment.
    (2) A regulation issued by the Secretary as provided in this
subsection shall include any monitoring requirements that the Sec-
retary determines appropriate for bottled water.
    (3) A regulation issued by the Secretary as provided in this
subsection shall require the following:
        (A)  In the case of contaminants for which a maximum con-
    taminant level is established in  a national primary drinking
    water regulation under section  1412  of  the  Safe Drinking
    Water Act  (42 U.S.C. 300g-l), the regulation under this sub-
    section  shall establish a maximum contaminant level for the
    contaminant  in bottled water which is  no less stringent than
    the maximum contaminant level  provided in the national pri-
    mary drinking water regulation.
        (B)  In the case of contaminants for  which a treatment
    technique is established in a national primary  drinking water
    regulation under section 1412 of  the Safe Drinking Water Act
    (42 U.S.C.  300g-l), the regulation under this subsection shall
    require  that bottled  water be subject to requirements no less
    protective of the public health than those  applicable to water
    provided by public  water systems using  the treatment tech-
    nique required by the national primary  drinking water regula-
    tion.
    (4)(A) If the Secretary does not promulgate a regulation under
this subsection within the period described in paragraph  (1), the
national  primary drinking water regulation referred  to in  para-
graph (1) shall be considered, as of the date on which the Secretary
is required  to establish a regulation  under paragraph (1), as the
regulation applicable under this subsection to bottled water.
    (B) In the case of a national primary drinking water regulation
that pursuant to  subparagraph (A) is considered to be a standard
of quality regulation, the Secretary shall, not later  than the appli-
cable date referred to in such subparagraph, publish in the Federal
Register a notice—
        (i)  specifying the contents of  such regulation, including
    monitoring requirements; and
        (ii) providing that for purposes of this paragraph the effec-
    tive date for  such regulation  is the same as the effective date
    for the regulation for purposes of the Safe Drinking Water Act
    (or, if the exception under paragraph (1) applies to the regula-
    tion, that the effective date for the regulation is not later than
    2  years  and 180 days after the date of enactment of the Safe
    Drinking Water Act Amendments  of 1996).

                    VITAMINS AND MINERALS

    SEC.  411.  [350] (a)(l) Except as provided in paragraph (2)—
       (A)  the Secretary may not establish, under section 201(n),
    401,  or  403, maximum limits on  the potency of any synthetic
    or natural vitamin or mineral within a food to  which this sec-
    tion applies;
       (B) the Secretary may not classify any natural  or synthetic
    vitamin or mineral (or combination thereof) as a  drug solely

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Sec. 411	FEDERAL FOOD, DRUB, AND  COSMETIC ACT	182

    because it exceeds the level of potency which the Secretary de-
    termines is nutritionally rational or useful;
        (C) the Secretary may not limit, under section 201(n), 401,
    or 403, the combination or number of any synthetic or natu-
    ral—
            (i) vitamin,
            (ii) mineral, or
            (iii) other ingredient of food,
    within a food to which this section applies.
    (2) Paragraph (1) shall not apply in the case of a vitamin, min-
eral, other ingredient of food, or food, which is represented for use
by individuals in the treatment or management of specific  diseases
or disorders, by children, or by pregnant  or lactating women. For
purposes of this subparagraph x, the term "children" means individ-
uals who are under the age of twelve years.
    (b)(l) A food to which this section  applies shall not be deemed
under section 403 to be misbranded solely because its label bears,
in accordance with section 403(i)(2), all the ingredients in  the food
or its advertising contains references to ingredients in the food
which are not vitamins or minerals.
    (2) The labeling for any food to which this section applies may
not list its ingredients which are  not  dietary supplement ingredi-
ents described in section 201(fF) (i) except as a part of a list of all
the ingredients  of such food, and (ii) unless such ingredients are
listed in accordance with applicable regulations under section 403.
To the extent that compliance with clause (i) of this subparagraph
is impracticable or results in deception or unfair competition, ex-
emptions shall be established by  regulations promulgated by the
Secretary.
    (c)(l) For purposes of this section,  the term "food to  which this
section applies" means a food for humans which is  a food for spe-
cial dietary use—
        (A) which is or contains  any natural or synthetic vitamin
    or mineral, and
        (B) which—
            (i) is intended for ingestion in tablet, capsule, powder,
        softgel, gelcap, or liquid form, or
            (ii) if not intended for ingestion in such a form, is not
        represented as conventional food and is not represented for
        use as a sole item of a meal or of the diet.
    (2) For purposes of paragraph (l)(B)(i), a food shall be consid-
ered as intended for ingestion in liquid form only if it is formulated
in a fluid carrier and it is intended for ingestion in daily quantities
measured in drops or similar small units of measure.
    (3) For purposes of paragraph (1) and of section 403 (j) insofar
as that section  is applicable to food to which this section applies,
the  term "special dietary use"  as applied to food used  by man
means a particular use for which a food purports or is represented
to be used, including but not limited to the following:
        (A) Supplying a special dietary need that exists by  reason
    of a physical, physiological, pathological,  or other condition, in-
    cluding but not limited to the condition of disease, convales-
  1 Probably should be "paragraph".

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183	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 412

    cence, pregnancy, lactation, infancy, allergic hypersensitivity to
    food, underweight, overweight, or the need  to control the in-
    take of sodium.
        (B)  Supplying a vitamin, mineral, or other ingredient for
    use by man to supplement his diet by increasing the total die-
    tary intake.
        (C)  Supplying a special dietary need by reason of being a
    food for use as the sole item of the diet.

              REQUIREMENTS FOR INFANT FORMULAS

    SEC. 412. [350a]  (a) An infant  formula, including an infant
formula powder, shall be deemed to be adulterated if—
        (1)  such  infant formula  does not provide nutrients as re-
    quired by subsection (i),
        (2) such infant formula does not meet the quality factor re-
    quirements prescribed by the Secretary under subsection (b)(l),
    or
        (3) the processing of such infant  formula is not in compli-
    ance with  the  good manufacturing practices and  the quality
    control  procedures prescribed by  the  Secretary  under  sub-
    section (b)(2).
    (b)(l) The Secretary shall by regulation establish requirements
for quality factors for infant formulas to the extent possible consist-
ent with current scientific knowledge,  including quality factor re-
quirements for the nutrients required by subsection (i).
    (2)(A) The  Secretary shall by regulation establish  good manu-
facturing practices for infant formulas, including quality control
procedures that the Secretary determines are necessary to assure
that an infant  formula provides  nutrients in accordance with this
subsection and subsection (i) and is manufactured in a manner de-
signed to prevent adulteration of the infant formula.
    (B) The good manufacturing practices and quality  control pro-
cedures prescribed by  the Secretary under subparagraph  (A) shall
include requirements for—
        (i) the testing, in accordance with paragraph (3) and by the
    manufacturer of an infant formula or an agent of  such manu-
    facturer, of each batch  of infant  formula for each  nutrient re-
    quired by subsection  (i) before the distribution of such batch,
        (ii)  regularly scheduled testing, by the manufacturer of an
    infant formula or  an agent of such manufacturer, of samples
    of infant formulas during the shelf life of such formulas to en-
    sure that such formulas are in compliance with this section,
        (iii) in-process controls including, where necessary, testing
    required by good manufacturing  practices designed to prevent
    adulteration of each batch of infant formula, and
        (iv) the conduct by  the manufacturer of an infant formula
    or an agent of such manufacturer of regularly scheduled audits
    to determine that such manufacturer has  complied  with  the
    regulations prescribed under subparagraph (A).
In prescribing requirements for audits under clause (iv), the Sec-
retary shall provide that such audits be conducted by appropriately
trained individuals who do not have any direct responsibility for
the manufacture or production of infant formula.

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Sec. 412	FEDERAL FOOD, DRUB, AND COSMETIC ACT	184

    (3)(A) At the final product stage, each batch of infant formula
shall be tested for vitamin A, vitamin Bl, vitamin C, and vitamin
E to ensure that such infant formula is in compliance with the re-
quirements of this subsection and subsection (i) relating to such vi-
tamins.
    (B) Each nutrient premix used in the manufacture of an infant
formula shall be tested for each relied upon nutrient required by
subsection (i) which  is contained in such  premix to ensure  that
such premix is in compliance with its specifications or certifications
by a premix supplier.
    (C) During the manufacturing process  or at the final product
stage and before distribution of an infant  formula, an  infant for-
mula  shall be tested for  all nutrients required to be included in
such formula by subsection (i)  for which testing has not been con-
ducted pursuant to subparagraph  (A) or (B). Testing under this
subparagraph shall be conducted to—
        (i) ensure that each batch of such infant formula is in com-
    pliance with the requirements of subsection (i) relating to such
    nutrients, and
        (ii) confirm that nutrients contained in any nutrient pre-
    mix used in such infant formula are present in each batch of
    such infant formula in the proper concentration.
    (D) If the Secretary adds a nutrient to the list of nutrients in
the table in subsection (i), the Secretary shall by regulation require
that the manufacturer of an infant formula test each batch of such
formula for such new nutrient in  accordance with  subparagraph
(A), (B), or (C).
    (E) For purposes of this paragraph, the term "final product
stage"  means the point in the manufacturing process, before dis-
tribution of an infant formula, at which an infant  formula is ho-
mogenous and is not subject to  further degradation.
    (4)(A) The Secretary shall by regulation establish requirements
respecting the retention of records. Such requirements shall pro-
vide for—
        (i) the retention  of all records  necessary to demonstrate
    compliance with the good manufacturing practices and quality
    control procedures prescribed  by the  Secretary  under para-
    graph (2), including records containing the results of all testing
    required under paragraph (2)(B),
        (ii) the retention of all certifications or guarantees of anal-
    ysis by premix suppliers,
        (iii) the retention by a premix supplier of all records nec-
    essary to confirm the accuracy of all premix certifications and
    guarantees of analysis,
        (iv) the retention of—
            (I) all records pertaining to the microbiological quality
        and purity of raw materials used in infant formula powder
        and in finished infant formula, and
            (II) all records  pertaining to food packaging materials
        which show that such materials do  not cause an infant for-
        mula to be  adulterated within the meaning  of section
        402(a)(2)(0,

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 185	FEDERAL FOOD,  DRUG, AND COSMETIC ACT	Sec. 412

         (v) the retention of all records of the results of regularly
     scheduled audits conducted pursuant to the requirements pre-
     scribed by the Secretary under paragraph  (2)(B)(iv), and
         (vi) the retention of all complaints and the maintenance of
     files with respect to, and the review of, complaints concerning
     infant formulas which may reveal the possible existence of a
     hazard to health.
     (B)(i) Records required under subparagraph (A) with respect to
 an infant formula shall be retained for at least one year after the
 expiration of the  shelf life of such infant  formula. Except as pro-
 vided in clause (ii), such records shall be made available to the Sec-
 retary for review and duplication upon request of the Secretary.
     (ii) A  manufacturer need only provide written assurances to
 the Secretary that the regularly scheduled audits required by para-
 graph (2)(B)(iv) are being conducted by the manufacturer, and need
 not make  available to  the  Secretary the actual written reports of
 such audits.
    (c)(l) No  person shall introduce or deliver for introduction into
 interstate commerce any new infant formula unless—
         (A) such  person has, before introducing such new infant
    formula,  or delivering  such new infant formula for introduc-
    tion, into interstate commerce, registered with the Secretary
    the name of such person, the place of business of such person,
    and all establishments at which  such person intends to manu-
    facture such new infant formula, and
         (B) such person has at least 90 days before marketing such
    new infant formula, made the submission to the Secretary re-
    quired by subsection (c)(l).
    (2) For purposes of paragraph (1), the term "new infant  for-
 mula" includes—
         (A) an infant formula manufactured by a person which has
    not previously manufactured an infant formula, and
         (B) an infant formula manufactured by a person which has
    previously manufactured  infant formula and in which there is
    a major change,  in processing or formulation, from a  current
    or any previous formulation produced by such manufacturer.
 For purposes  of this  paragraph, the  term "major change" has  the
 meaning given to such term in section 106.30(c)(2)  of title 21, Code
 of Federal  Regulations  (as in  effect on August 1, 1986), and guide-
 lines issued thereunder.
    (d)(l) A person shall, with respect to any infant formula sub-
ject to subsection (c), make a submission  to  the Secretary which
 shall include—
        (A) the quantitative formulation of the infant formula,
        (B) a description of any  reformulation of the formula or
    change in processing of the infant formula,
        (C) assurances that the infant formula will not be mar-
    keted unless it meets  the requirements  of subsections  (b)(l)
    and  (i), as demonstrated by  the  testing required under sub-
    section (b)(3), and
        (D) assurances that the processing of the infant formula
    complies with  subsection (b)(2).
    (2) After  the first production of an infant formula  subject to
 subsection (c), and before the introduction into  interstate commerce

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Sec. 412	FEDERAL FOOD,  DRUG, AND COSMETIC ACT	186

of such formula, the manufacturer of such formula shall submit to
the Secretary, in such form as may be prescribed by the Secretary,
a written verification which  summarizes test results and records
demonstrating that such formula complies with the requirements of
subsections  (b)(l),  (b)(2)(A),  (b)(2)(B)(i),  (b)(2)(B)(iii),  (b)(3)(A),
(b)(3)(C), and (i).
    (3) If the manufacturer of an infant formula for commercial or
charitable distribution for human consumption  determines that a
change in the formulation of the formula or a change in the proc-
essing of the formula may affect whether the formula is adulter-
ated under subsection (a), the manufacturer shall, before the first
processing of such formula, make the submission to the  Secretary
required by paragraph (1).
    (e)(l) If the manufacturer of an infant formula has knowledge
which reasonably  supports the  conclusion that  an infant formula
which has been processed by the manufacturer  and which has left
an establishment subject to the control of the manufacturer—
        (A)  may not provide the nutrients required by  subsection
    (i), or
        (B) may be otherwise adulterated or misbranded,
the  manufacturer  shall  promptly notify the  Secretary of  such
knowledge. If the Secretary determines that the  infant formula pre-
sents a  risk to human health, the manufacturer shall immediately
take  all  actions necessary to recall shipments  of such infant for-
mula from all wholesale  and retail establishments, consistent with
recall regulations and guidelines issued by the Secretary.
    (2) For purposes of paragraph (1), the term  "knowledge" as ap-
plied to  a manufacturer means (A) the actual knowledge that the
manufacturer had, or (B)  the knowledge which a reasonable person
would have had under  like circumstances  or  which would  have
been obtained upon the exercise of due care.
    (f)(l) If a recall of infant formula is begun by a manufacturer,
the recall shall be  carried out in accordance  with  such require-
ments as the  Secretary shall prescribe under paragraph (2) and—
         (A)  the Secretary shall, not later than  the 15th day after
    the  beginning of such recall and at  least once every 15 days
    thereafter until the  recall  is terminated,  review the  actions
    taken under the recall to determine  whether the recall meets
    the requirements prescribed under paragraph (2), and
         (B) the manufacturer shall, not later  than the 14th day
    after the  beginning  of such recall and at least once every 14
    days thereafter until the recall is terminated, report to the Sec-
    retary the actions taken to implement the recall.
    (2)  The Secretary shall by  regulation prescribe the scope and
extent of recalls of  infant formulas necessary and appropriate for
the degree of risks to human health presented by the formula sub-
ject to the recall.
    (3)  The Secretary shall  by regulation require  each manufac-
turer of an infant formula who begins a recall of such formula be-
cause of a risk to human health to  request each retail establish-
ment at which such formula is  sold or available for sale to post at
the point of purchase of such formula a notice of such recall at such
establishment for such  time that the Secretary determines  nec-
essary to inform the public of such recall.

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 187	FEDERAL FOOD, DRUB, AND COSMETIC ACT	Sec. 412

    (g)(l) Each manufacturer of an infant formula shall make and
 retain such records respecting the  distribution  of the infant for-
 mula through any establishment owned or operated by such manu-
 facturer as may be necessary to effect and monitor recalls of the
 formula. Such  records shall be retained for at least one year after
 the expiration of the shelf life of the infant formula.
    (2) To the extent that the Secretary  determines that records
 are not being  made or maintained  in accordance with paragraph
 (1), the Secretary may by regulation prescribe the records required
 to be made under  paragraph (1) and requirements respecting the
 retention of such records under such paragraph. Such regulations
 shall  take effect on such date as the Secretary prescribes but not
 sooner than the 180th day after the date such regulations are pro-
 mulgated.  Such regulations  shall apply only with respect to dis-
 tributions of infant formulas made after such effective date.
    (h)(l) Any  infant formula which is represented and labeled for
 use by an infant—
        (A) who has an inborn error of metabolism or a  low birth
    weight, or
        (B) who otherwise has an unusual medical or dietary prob-
    lem,
 is exempt from the  requirements of subsections (a), (b), and (c). The
 manufacturer of an infant formula  exempt under this paragraph
 shall, in the case of the exempt formula, be required to provide the
 notice required by  subsection (e)(l)  only with respect to  adultera-
 tion or misbranding described in subsection (e)(l)(B) and to comply
 with the regulations prescribed by the Secretary under paragraph
 (2).
    (2) The Secretary may by regulation establish terms and condi-
 tions for the exemption of an infant formula from the requirements
 of subsections (a), (b), and (c). An exemption of  an infant formula
 under paragraph (1) may  be  withdrawn by the  Secretary if such
 formula is not  in compliance with applicable terms and conditions
 prescribed under this paragraph.
    (i)(l) An infant formula  shall contain nutrients in accordance
with the table  set out in this subsection or, if revised by the Sec-
retary under paragraph (2), as so revised.
    (2) The Secretary may by regulation—
        (A) revise  the  list of nutrients in the table in  this  sub-
    section, and
        (B) revise the required level for any nutrient required by
    the table.

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Sec. 413	FEDERAL FOOD, DRU6. AND COSMETIC  ACT	188


                            NUTRIENTS

           Nutrient                     Minimum1              Maximum1

Protein (gin) 	  1.82  	  4.5.
Fat:
   gm 	  3.3 	  6.0.
   percent cal 	  30.0  	  54.0.
Essential fatty acids (linoleate):
   percent cal 	  2.7 	
   mg 	  300.0 	
Vitamins:
   A (IU) 	  250.0 (75 ng)3	  750.0 (225 fig).3
   D (IU)	  40.0  	  100.0.
   K(ug) 	  4.0 	
   E (ID)	  0.7 (with 0.7 lU/gm linoleic
                                acid).
   C (ascorbic acid) (mg) 	  8.0 	
   Bi (thiamine) (jig) 	  40.0  	
   B2 (riboflavin) (ng) 	  60.0  	
   B6 (pyridoxine) (|ig)	  35.0  (with  15 ug/gm of pro-
                                tein in formula).
   B.2 (H«> -,	  g-16
    Niacm (ug)	  250.0
         cid (u
    Folic acid (ng)	  4.0
    Pantothenic acid (ug)	  300.0 	
    Biotin (fig) 	  1.54  	
    Choline (mg) 	  7.04  	
    Inositol (mg) 	  4.04  	
Minerals:
    Calcium (mg)	  50.05 	
    Phosphorus (mg)  	  25.05 	
    Magnesium (mg)  	  6.0 	
    Iron (mg)	  0.15  	
    Iodine ((ig) 	  5.0 	
    Zinc (mg) 	  0.5 	
    CopperTug) 	  60.0  	
    Manganese (tig)	  5.0 	
    Sodium (mg) 	  20.0  	  60.0.
    Potassium (mg) 	  80.0  	  200.0.
    Chloride (mg) 	  55.0  	  150.0.	
 'Stated per 100 kilocalories.
 2 The source of protein  shall be at least nutritionally equivalent to casein.
 3Retinol equivalents.
 4 Required to be included in this amount only in formulas which are not milk-based.
 6 Calcium to phosphorus ratio must be no less than 1.1 nor more than 2.0.

                     NEW DIETARY INGREDIENTS

    SEC. 413.  [350b]  (a)  IN GENERAL.—A  dietary  supplement
which contains  a new dietary  ingredient shall be deemed adulter-
ated  under section 402(f) unless it meets  one of the following re-
quirements:
         (1)  The dietary supplement contains only  dietary ingredi-
    ents  which have been  present  in the food supply as an article
    used for food in a form in which the food has not been chemi-
    cally altered.
         (2) There is a history  of use or other evidence of safety es-
    tablishing  that the  dietary ingredient  when used under  the
    conditions recommended or suggested in the  labeling  of the di-
    etary supplement will reasonably  be expected to be  safe and,
    at least 75  days before being introduced or delivered  for intro-
    duction  into interstate  commerce,  the  manufacturer or dis-
    tributor of the dietary ingredient or dietary supplement pro-
    vides the Secretary with information, including any citation to

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189	FEDERAL FOOD, DRU6, AND  COSMETIC ACT	Sec. 413

    published articles, which is the basis on which the manufac-
    turer or distributor has concluded that a dietary supplement
    containing such dietary ingredient will reasonably be expected
    to be safe.
The Secretary shall keep confidential any  information  provided
under paragraph (2) for 90 days following its receipt. After the ex-
piration of such 90 days, the Secretary  shall place such information
on  public  display, except matters  in  the  information which are
trade secrets or otherwise confidential,  commercial information.
    (b) PETITION.—Any person may file with the Secretary a peti-
tion proposing the issuance of an order prescribing the conditions
under which a new dietary ingredient under its intended conditions
of use will reasonably be expected to be safe. The Secretary shall
make a decision on such petition within 180 days of the date the
petition is filed with the Secretary. For purposes  of chapter 7 of
title 5, United States  Code,  the decision of the  Secretary  shall be
considered final agency action.
    (c) DEFINITION.—For purposes of this section, the term "new di-
etary ingredient"  means a dietary ingredient that was not mar-
keted in the United States before October 15, 1994 and  does not
include any dietary ingredient which was marketed in the United
States before October 15, 1994.
       .S GOVERNMENT PRINTING OFFICE: 1998 615-003/60633

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