Federal Register/Vol.  71,  No. 99/Tuesday,  May 23, 2006/Notices
                                                                       29623
regulations.11 The GARB regulations set
emission standards  for these engines
commencing with model year 2001  for
certification and with model year 2004
for in-use compliance. There  are two
sets of standards depending on the size
of the engine; one set for LSI engines
less than or equal to 1.0 liters
displacement, and the other for LSI
engines greater than 1.0 liters
displacement. For the smaller LSI
engines, GARB set standards for HC plus
Nox and for CO at static levels for model
year 2002 and beyond, and 100% of a
manufacturer's sales must meet the
standards each year. For the larger LSI
engines, GARB approved two tiers of
emission levels. For Tier 1,
manufacturers are able to phase-in
compliance at certification with 25% of
the sales for 2001, 50% for 2003, and
75% for 2003, and manufacturers have
no in-use compliance requirement. For
Tier 2, beginning with the 2004 model
year, manufacturers have to meet the
standards at certification with 100% of
sales, and are subject to in-use
compliance with a less stringent
standards for model years 2004 through
2006 (with an engine durability period
of 3500  hours or 5 years) and full in-use
standards for model years 2007 and
beyond  (with a durability period of 5000
hours or 7 years).
  To accompany the new standards,
GARB also adopted regulations
requiring manufacturer production line
testing (along with GARB authority to
conduct Selective Enforcement Audits),
manufacturer required in-use testing, an
in-use emission credit program,
permanent emission labels, and
emission warranties. GARB also adopted
provisions to provide relief to small
volume manufacturers (annual
production under 2000 engines)
basically by delaying the time when
they must comply with in-use standards
until 2004.
  EPA offered the opportunity for a
public hearing, and requested public
comments, on the GARB authorization
request, as the Act requires us to do, by
publication of a Federal Register notice
to such  effect on January 12, 2005.12
There was no request for a public
hearing, nor were any comments
received on the GARB authorization
  11 These engines are often derived from
automobile engines, although they have less
sophisticated fuel and emission control systems,
and are fueled usually by either gasoline or
liquified petroleum gas (LPG). Typical applications
for these LSI engines are forklifts, portable
generators, large turf care equipment, irrigation
pumps, welders, air compressors, scrubber/
sweepers, and airport service vehicles. GARB Initial
Staff Report, Docket Entry OAR-2004-0404-0008,
pi.
  12 70 FR 2151 (January 12, 2005).
request. Therefore, EPA has made this
determination based on the information
submitted by GARB in its request.
(C) Authorization Decision
  EPA has decided to grant California
authorization to enforce its regulations
setting emission standards and other
requirements for large off-road spark-
ignition engines. In its request letter,
GARB stated that these LSI regulations
will not cause the California nonroad
standards, in the aggregate, to be less
protective of public health and welfare
than the applicable Federal standards.
GARB also stated that California's need
for the emission reductions expected
from the LSI regulations remains
compelling. Finally,  regarding
consistency with section 209, GARB
stated that the LSI regulations  (1) apply
only to nonroad engines and vehicles
and not to motor vehicles or engines, (2)
apply only to those nonroad engines
and vehicles which are not included in
the preempted categories, and  (3) do not
raise any concerns of inadequate
leadtime or technological feasibility or
impose any certification requirements
inconsistent with Federal requirements.
  EPA agrees with all GARB findings
with regard to the provisions listed.
Additionally, no information was
presented to EPA by any party which
would demonstrate that California did
not meet the burden  of satisfying the
statutory criteria of section 209(e).  For
these reasons, EPA authorizes  California
to enforce these LSI regulations.
  My decision will affect not only
persons in California but also the
manufacturers outside the State who
must comply with California's
requirements in order to produce
nonroad engines and vehicles for sale in
California. For this reason, I hereby
determine and find that this is a final
action of national applicability.
  Under section 307(b)(l) of the Act,
judicial review of this final action may
be sought only in the United States
Court of Appeals for the District of
Columbia Circuit. Petitions for review
must be filed by July 24, 2006. Under
section 307(b)(2) of the Act, judicial
review of this final action may not be
obtained in subsequent enforcement
proceedings.
  As with past authorization decisions,
this action is not a rule as defined by
Executive Order 12866. Therefore, it is
exempt from review  by the Office of
Management and Budget as required for
rules  and regulations by Executive
Order 12866.
  In addition, this action is not a rule
as defined in the Regulatory Flexibility
Act, 5 U.S.C. 601(2).  Therefore, EPA has
not prepared a supporting regulatory
flexibility analysis addressing the
impact of this action on small business
entities.
  The Congressional Review Act, 5
U.S.C. 801 et seq., as added by the Small
Business Regulatory Enforcement
Fairness Act of 1996, does not apply
because this action is not a rule, for
purposes of 5 U.S.C. 804(3).
  Finally, the Administrator has
delegated the authority to make
determinations regarding authorizations
under section 209(e) of the Act to the
Assistant Administrator for Air and
Radiation.
  Dated: May 15, 2006.
William L. Wehrum,
A cting Assistant A d minis tra tor for Air and
Radiation.
[FR Doc. E6-7834 Filed 5-22-06; 8:45 am]
BILLING CODE 6560-50-P
ENVIRONMENTAL PROTECTION
AGENCY

[FRL-8173-5; Docket I.D. No. EPA-HQ-
ORD-0116]

Harmonization in Interspecies
Extrapolation: Use of BW3'4 as Default
Method in Derivation of the Oral RfD

AGENCY: Environmental Protection
Agency (EPA).
ACTION: Notice of Peer-Review
Teleconference with opportunity for
public comment.

SUMMARY: EPA is announcing that
Versar, Inc., an EPA contractor for
external scientific peer review, plans to
convene an independent panel of
experts and  organize and conduct an
external peer review meeting to review
the draft document titled,
"Harmonization in Interspecies
Extrapolation: Use of BW3'4 as Default
Method in Derivation of the Oral RfD"
(EPA/630/R-06/001). The peer review
meeting is planned to take place by
teleconference. On Februrary 15, 2006,
EPA announced a 60-day public
comment period for the draft document
(71 FR 7958). The draft document was
prepared by the Agency's Risk
Assessment Forum.
  The public comment period and the
external peer review are separate
processes that provide opportunities for
all interested parties to comment on the
document. In addition to considering
public comments submitted in
accordance with the February  15, 2006,
announcement of a public comment
period, EPA intends to forward those
comments to Versar, Inc. for the external
peer review panel prior to the
teleconference.

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29624
Federal Register/Vol.  71, No. 99/Tuesday, May 23, 2006/Notices
  EPA is releasing this draft document
solely for the purpose of pre-
dissemination peer review under
applicable information quality
guidelines. This document has not been
formally disseminated by EPA. It does
not represent and should not be
construed to represent any Agency
policy or determination.
  The public will be given an
opportunity to observe and provide oral
comments at this teleconference by
registering with Versar, Inc. (see FOR
FURTHER INFORMATION CONTACT, below).
The draft document and the charge
questions for EPA's  external peer review
are available primarily via the Internet
on the Risk Assessment Forum's home
page under the External Review Drafts
menu at http://cfpub.epa.gov/ncea/raf/
index.cfm. In preparing a final report,
EPA will consider Versar Inc.'s report of
the comments and recommendations
from the external peer review meeting
and any public comments that EPA
receives in  accordance with the
February 15, 2006, notice (71 FR 7958).
DATES: The peer review teleconference
will be held on June 14, 2006, from 9
a.m. to no later than 5 p.m., with a break
for lunch. The teleconference may end
earlier than 5 p.m. if less time is needed
for the reviewers to complete their
discussion. Time will be provided for
public observers who  wish to make
comments on the document.
ADDRESSES: The draft  "Harmonization
in Interspecies Extrapolation: Use of
BW3/4 as Default Method in Derivation
of the Oral RiD" is available primarily
via the Internet on the Risk Assessment
Forum's home page  under the External
Review Drafts menu at http://
cfpub.epa.gov/ncea/raf/index.cfm. A
limited number of paper copies are
available from the Technical
Information Staff, NCEA-W by
telephone: 202-564-3261 or by
facsimile: 202-565-0050. If you are
requesting a paper copy, please provide
your name, mailing  address, and the
document title, "Harmonization in
Interspecies Extrapolation: Use of BW3'4
as Default Method in Derivation of the
Oral RfD." Copies are  not available from
Versar, Inc.
FOR FURTHER INFORMATION CONTACT:
Members of the public may call into the
teleconference as observers, and there
will be a limited time  for comments
from the public. In order to participate,
you should contact Mr. Andrew Oravetz
of Versar, Inc. at aoravetz@versar.com or
by phone at 703-642-6832 to register.
You will be asked for your name,
affiliation, city and state, and contact
information. When registering, please
also indicate whether you would like  to
                make a statement during the call. Time
                for public comments is limited, and
                reservations will be accepted on a first-
                come, first-served basis. At a time before
                June 14, 2006, registrants will be given
                the call-in information for the peer
                review teleconference.
                  For technical information, please
                contact Resha M.  Putzrath, Risk
                Assessment Forum; telephone: 202-
                564-3229; facsimile: 202-565-0062; or
                e-mail: putzrath.resha@epa.gov.

                SUPPLEMENTARY INFORMATION:

                I. Information About the Document

                  The Agency endorses a hierarchy of
                approaches to derive human equivalent
                oral exposures from data from
                laboratory animals, with the preferred
                approach being physiologically based
                toxicokinetic modeling. Intermediate
                approaches include using  some
                chemical-specific information. In lieu of
                data to support either of these
                approaches, body weight scaling to the
                % power (BW3/4)  would be endorsed as
                a general default procedure to
                extrapolate lexicologically equivalent
                doses of chronic orally administered
                agents from  laboratory animals to
                humans for the purposes of deriving an
                oral Reference Dose (RfD). Use of BW3'4
                in derivation of RfD values would be
                parallel with current Agency use in
                derivation of cancer oral slope factors.
                Thus, this paper would harmonize the
                two main Agency oral dose-response
                extrapolation procedures.  This
                generalized  default procedure is viewed
                as an informed, species-specific,
                dosimetric adjustment factor (DAF) that
                addresses predominantly toxicokinetic
                and some toxicodynamic aspects of the
                interspecies uncertainty factor UFA.  Use
                of this procedure  would result in
                derivation of a human equivalent
                exposure, specifically a human
                equivalent dose (HED) that is to be used
                in derivation of the oral RfD in a manner
                parallel to the human equivalent
                concentration (HEC)  in derivation of an
                inhalation RfC.
                  Dated: May 15, 2006.
                George Alapas,
                Deputy Director, National Center for
                Environmental Assessment.
                [FR Doc. E6-7836 Filed 5-22-06; 8:45 am]
                BILLING CODE 6560-50-P
ENVIRONMENTAL PROTECTION
AGENCY
[EPA-HQ-ORD-2006-0187; FRL-8173-1]

Human Studies Review Board (HSRB);
Notification of a Public Teleconference
To Review Its Draft Report From the
April 4-6,  2006 HSRB Meeting

AGENCY: Environmental Protection
Agency (EPA).
ACTION: Notice.

SUMMARY:  The EPA Human Studies
Review Board (HSRB) announces a
public teleconference meeting to discuss
its draft HSRB report from the April 4-
6, 2006 HSRB meeting.
DATES: The date for the teleconference
will be held on June 8, 2006, from 1:30-
4 p.m. (Eastern Time).
  Location: The meeting will take place
via telephone only.
  Meeting Access: For information on
access or services for individuals with
disabilities, please contact the DFO at
least 10 business days prior to the
meeting using the information under
FOR FURTHER INFORMATION CONTACT so
that appropriate arrangements can be
made.
  Procedures for Providing Public Input:
Interested members of the public may
submit relevant written or oral
comments for the HSRB to consider
during the advisory process.  Additional
information concerning submission of
relevant written or oral comments is
provided in Unit I.D. of this notice.
FOR FURTHER INFORMATION CONTACT:
Members of the public who wish to
obtain the call-in number and access
code to participate in the telephone
conference, request a current draft copy
of the Board's report or who wish
further information may contact Paul I.
Lewis, Designated Federal Officer
(DFO), EPA, Office of the Science
Advisory,  (8105), Environmental
Protection Agency, 1200 Pennsylvania
Avenue, NW., Washington, DC 20460;
or via telephone/voice mail at (202)
564-8381  or via e-mail at
lewis.paul@epa.gov. General
information concerning the EPA HSRB
can be on the EPA Web site at http://
www.epa.gov/osa/hsrb/.
ADDRESSES: Submit your written
comments, identified by Docket ID No.
EPA-HQ-ORD-2006-0187, by one  of
the following methods: http://
www.regulations.gov: Follow the on-line
instructions for submitting comments.
  E-mail: ORD.Docket@epa.gov.
  Mail: ORD Docket, Environmental
Protection Agency, Mailcode: 28221T,
1200 Pennsylvania Ave., NW.,
Washington, DC 20460.

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