EPA-600/3-84-101
                           ATMOSPHERIC  TRANSPORT OF TOXAPHENE
                                    TO  LAKE  MICHIGAN
                                           by
                                       C.  P.  Rice

                             Great Lakes Research Division
                          Institute of Science and Technology
                               The  University of  Michigan
                               Ann  Arbor,  Michigan  48109
                                      P.  J.  Samson

                     Department  of  Atmospheric and Oceanic Sciences
                              The  University of Michigan
                              Ann  Arbor,  Michigan  48109
                                       G.  Noguchi

                             Great Lakes Research Division
                          Institute of Science and Technology
                               The  University of  Michigan
                               Ann  Arbor,  Michigan  48109
                                     February 1984

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                                  ABSTRACT


     Atmospheric levels of toxaphene were monitored during the summer and fall
of 1981 at 4 locations:  Greenville, Mississippi, St. Louis, Missouri, Bridg-
man, Michigan, and Beaver Island, Michigan.  Each collection was conducted by
continuously sampling air during the first two weeks of the months of August,
September, October, and November.  The collected toxaphene was analyzed on a
capillary equipped electron capture gas chromatograph.  The average concen-
trations over the entire sampling period for each site were 7.39 ng/m3 in
Greenville, 1.18 ng/m3 in St. Louis, and 0.27 ng/m3 for Lake Michigan (Bridg-
man and Beaver Island combined).  The summer versus fall fluctuations in amount
of toxaphene at each site was 0.44 ng/m3 versus 0.26 ng/m3 for Bridgman;
1.73 ng/m3 versus 0.63 ng/m3 for St. Louis; and 9.05 ng/m3 versus 4.34 ng/m3
for Greenville.  The maximum monthly average occurred in September for all of
these collections.  Diagnostic modeling to describe possible air transport of
toxaphene showed that at all receptor locations the air transport corridor for
toxaphene was associated with southerly winds.  The strength of this corridor
increased from northern to southern measurement sites.  A flux estimate for
toxaphene deposition to the lake surface ranged from 3,360 to 6,720 kg/yr.
                                                                1   • . .
                                       iii

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                                  CONTENTS









Abstract	   ill




List of Figures	    vi




List of Tables	viii




Introduction	     1




Methods	     5




    Air Collection	     5




    Extraction	    12




    Chromatographic Analysis	    12




    Quality Assurance	• • •    15




    Modeling	    19




Results and Discussion	    21




    Modeling of Atmospheric  Transport	    27




    Estimates of Atmospheric Flux of  Toxaphene  to  Lake  Michigan	    39




References	    43




Appendix A - Tests For Silicic Acid Fractionation  of  Toxaphene               Al




Appendix B - Letter to Houston Wells, Wells Laboratories,  Describing         Bl




               Study of Toxaphene Formulations  Used  In  Greenville,




               Mississippi

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                                  FIGURES
Number                                                                   Page

   1   Locations of the four sites where air was sampled for toxaphene
          in the summer and fall of 1981	 11

   2   Capillary chromatograms of toxaphene-containing air, rain and
          fish samples and EPA toxaphene standard.  The sculpin sample
          was analyzed on another project and is provided for comparison
          of the atmospheric data with biological residues.
          a) Air sample from Beaver Island (28 August to 31 August 1981)
          containing 0.054 ng/nH toxaphene;  b) Rain sample from
          Beaver Island (28 September to 2 October 1981) containing
          31.58 ng/L toxaphene;  c) Sculpin composite sample from Lake
          Michigan (17 June 1982) containing 0.718 ng/gm toxaphene;
          d) toxaphene standard (4 yL of 118 ng/mL).  G/C conditions -
          50 m fused silica column coated with SE-54 and temperature-
          programmed from 100 to 240° C at l°/min	 16

   3   Linearity plot of the electron capture detector response to
          toxaphene.  Plotted are the observed areas for the toxaphene
          standards versus their concentration (118, 222, and 444 ppb).  .. 17

   4   Simultaneous determinations of toxaphene in air measured
          at four sites lying along a general south-to-north transect
          from Greenville, Mississippi, through St. Louis, Missouri,
          and ending in the Lake Michigan area (Bridgman and
          Beaver Island, Michigan).  The vertical axes are in log
          units and the horizontal axes are calendar dates	 24

   5   Toxaphene in air measured at Beaver Island, Michigan, from
          28 August to 4 October 1981.  Vertical axis is in log
          units and the horizontal axis is in calendar dates	 25

   6   Unweighted probability of contribution during the sampling periods
          in units of 10~8/km2 in Bridgman, Mi. (approximate center of
          concentric rings) .	 28

   7   Weighted probability of contribution during the sampling periods
          in units of 10~8/km2 in Bridgman, Mi	 29

   8   Difference between Figures 6 and 7	 31

   9   Unweighted probability of contribution during the sampling periods
          in units of 10~8/km2 in St. Louis, Mo. (approximate center of
          concentric rings)	 32

  10   Weighted probability of contribution during the sampling periods
          in units of 10~8/km2 in St. Louis, Mo	 33

                                       vi

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11   Difference between Figures 9 and 10	 34

12   Unweighted probability of contribution during the sampling periods
        in units of 10~°/km^ in Greenville, Miss, (approximate center
        of concentric rings)	 35

13   Weighted probability of contribution during the sampling periods
        in units of 10~8/km2 in Greenville, Miss	 36

14   Difference between Figures 12 and 13	 37
                                    vii

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                                   TABLES
Number                                                                   Page
   1   Amount of toxaphene in air samples from Bridgman, Michigan;
          Beaver Island, Michigan; St. Louis, Missouri; and
          Greenville , Mississippi .	  7
       Duplicate results	 18

       Trend in toxaphene concentration at sampling sites for the
          summer and fall of 1981	 26
                                       viii

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                                INTRODUCTION








     Occurrence of toxaphene in the Great Lakes ecosystem is possibly one of




the most perplexing pollution problems to have ever occurred in this region.




Detectable levels of toxaphene were first evident in fish collected in 1974




from Lake Michigan and reported by the U.S. Fish and Wildlife Service (Rappe




et al. 1979).  Subsequent to this, additional data have been reported which




show toxaphene as a widespread contaminant of Great Lakes fish (Rice and




Evans, in press).  However, the use of toxaphene is primarily concentrated in




the southern states with few known applications of this pesticide in the Great




Lakes region.  The sources of toxaphene input to the Great Lakes have not yet




been determined.  Difficulty in analyzing environmental samples for toxaphene




has prevented thorough examination of the occurrence and distribution of




toxaphene in the environment.




     Like PCS, toxaphene is not just one compound.  In fact, it is a mixture




of at least 180 separate chemical compounds (Holmstead et al. 1974).  This




complex chemical makeup of toxaphene is the primary reason that its




environmental fate is so poorly understood.  Conventional packed column




separation with electron capture detection is not adequate to precisely




characterize toxaphene.  Fortunately, capillary chromatography techniques have




allowed better resolution of the component peaks and have improved the




confidence with which toxaphene is identified in samples.  However, selective




weathering of the original toxaphene peaks is believed to greatly alter the




ratio of peaks from the parent material (Zell and Ballschmiter 1980), as well




as create new peaks which are derived from the parent toxaphene but cannot be




used for matching and quantification in the usual sense.  In a study of the






                                      1

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 global  distribution of toxaphene,  Zell  and  Ballschmiter  (1980)  presented a




 technique using capillary separation and  analysis  of  fish residues for




 chlorinated hydrocarbons  which dealt with many of  the analytical difficulties




 presented by toxaphene.   In this method,  fractionation of the extracts with




 florisil chromatography was carried  out to  reduce  interferences from PCBs.




 This  type of approach has also been  successfully applied by others.   Ribick




 et al.  (1982) have analyzed fish tissues  for toxaphene using silica gel




 fractionation and  capillary chromatography while  others have relied on silica




 or florisil separation and packed  column analyses  (Schmitt et al. 1981,




 Bidleman et al. 1978, Devault et al. 1982).  All of these techniques are based




 on chromatographic methods which rely on retention time  matching as the basis




 for identification.  However, these  techniques do  not provide absolute




 chemical confirmation. To date, exact  identification of only 11 of the 177




 constituents in standard  toxaphene has  been made (Korte  et al.  1979).  Exact




 chemical identification of environmental residues, however, is difficult under




 the best conditions because levels are  usually low and many inferences have to




 be made.  Furthermore, toxaphene poses  additional  problems because standard




 electron impact mass spectrometry  is relatively insensitive to the components




 of toxaphene.  Positive chemical ionization techniques with mass spectrometry




 have  been used to identify some toxaphene components  in  residues from fish




 from  the Great Lakes (Ribick et al.  1982) and this is the only verification to




 date  that absolutely confirms the  presence  of toxaphene  in Great Lakes fish.




      Because of the analytical difficulties in measuring toxaphene in environ-




 mental  matrices, this study is as  much an analytical methods study as it is a




-study of environmental distribution.  As already mentioned, the perplexing




 question about toxaphene  in the Great Lakes is "How is it getting there?"

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The choices are limited as uses of this insecticide in the Great Lakes area

                                                                         u I--'"
                                                                             * ^,*
are few, with the preponderant uses occurring in the cotton and soybean    •-•;'


growing areas of the United States, e.g. the Cotton Belt.  Some use has been


reported for the Great Plains States, however for 1972 the total of 0.5


million Ibs. used by all the states from the region was only  1% of the Cotton


Belt usage.  In 1980, South Dakota used about 0.14 million Ibs. of toxaphene


which would represent about 1% of estimated 1980 U.S. usage (Rice and Evans,


in press).  No evidence for accidental spillage has been uncovered, and


manufacturing is not located in any of the Great Lakes states.  One proposal


contended that pulp bleaching may inadvertently produce toxaphene-like


materials in its waste liquor.  However, controlled laboratory tests under


optimal conditions for chlorine substitutions of pulping waste liquors could


not produce toxaphene-like compounds with greater than three  chlorine atoms


(presented by David Stalling, U.S. Fish and Wildlife Service, at EPA hearing


for cancellation of toxaphene, July 1982); toxaphene is composed mainly of six


to nine chlorine-containing compounds.  To many scientists, the only logical


choice left seems to be atmospheric transport.  Direct observations of this,


however, are limited.


     There is a good deal of experimental evidence to suggest that chemicals


like toxaphene, PCB, and DDT can be transported via the air for thousands of


miles (Bidleman and Olney 1974, Seba and Prospero 1971, Risebrough et al.


1968).  These data are strengthened by results from radioactive fallout


studies and by the recent concern over acid rain and its atmospheric link to


industrial centers.


     There are literature data to support the contention that high amounts of


toxaphene can be lost due to volatility (Nash et al. 1977, Sieber et al.

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   1979).  Long-range transport of toxaphene by way of the air is well documented


   both by direct observation of toxaphene in air at remote sites (Bidleman and


   Olney 1975, Bidleman et al . 1981) and by inference from finding the material


   in organisms at sites remote from the use of this material:  Great Lakes fish


   (Rappe et al . 1979); Antarctic cod from the South Pacific and an Arctic char


   from the Tyroleon Alps (Zell and Ballschmiter 1980); and an Arctic char from a


   lake in southern Sweden (Jansson et al . 1979).


        Use of air mass trajectory analyses coupled with pollutant measurements


   is a relatively new procedure for confirming sources of these materials.   Pack


   et al . (1977) used a trajectory model to map fluorocarbon transport in Europe.


   Others have performed long range mapping to follow ozone transport along the


   eastern coastline (Wolff et al. 1977).  Trajectory modeling was used by Rice


   and Olney (1978) to confirm that toxaphene transport to Bermuda could be tied


   to the southeastern region of the U.S.  This same type of trajectory modeling


   was utilized in this study in order to determine if a transport link to the


   cotton-growing regions (South Central to Southeast U.S.) could be established
 ~
   which coincided with high episodes of toxaphene occurring  over  Lake  Michigan.
 r 1
J-*' t
        Measurements of toxaphene in air, rain and surface water of  the Great


   Lakes have been reported (Rice and Evans, in press).  Therefore,  the potential


   for this route appears possible.  The purpose of  this study was to  examine


   atmospheric transport of toxaphene to the Great Lakes from the  high-use areas


   in the southern United States.  Establishing a reliable analytical  method


   became one of the most critical requirements to achieving  this  goal.

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                                    METHODS




AIR COLLECTION




     Toxaphene in the air was collected by passing air  through an  air  scrub-




bing system composed of a glass fiber filter  [only with the Hi-Vol®  (General




Metals Works, Inc., Village of Cleves, Ohio)  collectors],  and a  series of  soft




polyurethane foam plugs.  Two types of collectors were  used in this  study.




A Hi-Vol® collector was used for sampling air for toxaphene where  concentra-




tions were anticipated to be low to moderate, e.g. at the  Lake Michigan sampl-




ing locations on Beaver Island and at Bridgman, Michigan,  and in St. Louis,




Missouri.  A low volume air sampling device was used in Greenville,




Mississippi, where levels were anticipated to be high.  The high volume




sampler was a standard Hi-Vol® high volume sampling system modified  by adding




a stainless steel extension tube (23 cm long  and 9 cm dia.) behind the filter




holder (10 x 8") such that two to three 9-cm  diameter x 6.5 cm long




polyurethane foam plugs could be installed.   The air first passes  through  a




Gelman type "A" glass fiber filter rated at an exclusion size for  aerosols in




air of 1  m.  The bulk of the toxaphene is expected to  be  collected  as a gas




on the first foam plug.  The second plug in the series  was placed  as a backup




to check for possible breakthrough of toxaphene and to  also preclude back  flow




of contamination from the pumping apparatus.  The pump  was a General Metal




Works model GMWL-2000 blower.




     The entire sample holder was carefully cleaned prior  to use by  scrubbing




with soap and water, and solvent rinsing with pesticide grade acetone  and




methylene chloride.  Between each sample collection the collection assembly




was additionally rinsed with pesticide grade  solvents.  The filter and plugs




were carefully cleaned prior to use to free them of possible contaminants.

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The procedure for cleaning filters involved 450°C ignition in a muffle furnace




for 4 hours and storage in individual aluminum foil containers.  The plugs




were carefully cleaned prior to use according to the procedures of Billings




and Bidleman (1980), and periodically checked to guarantee their cleanliness




prior to use.




     Polyurethane foam plugs were also used for low volume collection.




These plugs measured 7 cm long x 3.5 cm diameter and were installed in glass




holders (10.5 cm long x 3.5 cm diameter).  No prefliters were used with these




collectors and two plugs were placed in series.  These plugs were also




precleaned according to Billings and Bidleman (1980).




     The flow for the Hi-Vol® collection was maintained at 0.55 to 1.1 m3/min




and the volumes for collection ranged from 1,161 to 4,100 m3 (Table 1).




The flow for the low-volume collection ranged from 7 to 10 L/min for the short




day collections and 2 to 5 L/min for the monthly average collections.  A Cast




pump was used to provide the vacuum for the low-volume collector and a Gilmont




flow meter (size #3, Cat. #F1300) was used to monitor the flow by taking




readings at 1 to 2-day intervals throughout the collection.  A Sprague/Textron




Gas Meter was used to measure the monthly air volumes collected.  These units




were calibrated at the University of Michigan Air Resources Laboratory prior




to employment.  To monitor the airflow of the Hi-Vol® collections, a




Marshalltown type flow gauge was used at Bridgman and Beaver Island.  Use of




these gauges involved observation of the gauge reading 2 to 3 times during  the




3-day sampling period and deriving an average reading for the total period  of




collection.  With the St. Louis collection, a continuous disc chart recorder




monitored the gas flow.  All of the General Metal Works pumps and gauges for

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the Hi-Vol® samples also were calibrated on the University of Michigan Air




Resources Laboratory gas meter prior to use in the field.




     The air collectors were operated at locations which were selected to




describe a possible transport pathway for toxaphene from Greenville, Missis-




sippi, a region known for high use of toxaphene in the past, to Lake Michigan.




Three locations, Greenville, Mississippi, St. Louis, Missouri, and Bridgman,




Michigan (Figure 1) were sampled simultaneously during four 2-week time




intervals through the summer and fall of 1981.  Samples were also collected




from Beaver Island, in northeastern Lake Michigan, during the second and third




collection period.  Rain was collected from Beaver Island during the last




sampling interval and also in April before air collection began in the spring.




Several attempts were made to collect rain at Bridgman.  However, the sample




collectors were vandalized in each instance and no rain samples were obtained.




The rain collectors were simple bucket collectors (total fallout collectors)




which were outfitted with screen wire rings on the top edges to discourage




birds from landing on them.  The buckets were carefully washed with soap and




water and rinsed with pesticide grade methylene chloride just prior to each




use.  For storage, the contents of the buckets were poured into pre-cleaned




brown glass 1-gal bottles.  The interior of the buckets were rinsed with




methylene chloride and these rinses were added to the sample bottles.




Additional methylene chloride (total  200 mL/bottle) was added for




stabilization in storage.




     Periodic blanks were taken at each of the sampling locations.  These  in-




volved all the steps of the setup for collection except for turning on the




pumps.  These samples were then broken down and returned to the laboratory  for




extraction and analysis as if they were actual samples.






                                      10

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EXTRACTION




     To extract the toxaphene residues from the filters and foam plugs,




each was cycled with pesticide grade petroleum ether for 12 hr in a Soxhlet




assembly.  Following petroleum ether extraction, extracts were concentrated to




approximately 5 to 10 mL and stored until analysis.  The rain samples were




extracted by mixing the sample with methylene chloride (1:3 v:v solvent to




water) on a ball-mill roller for 3 hrs.  Much thought went into how to work up




the samples in a way that would maximize the identification of the toxaphene




expected in the sample.  Our major interests were to study any weathering




which might be apparent and to avoid lengthy handling procedures which might




reduce our recoveries.  Nitration as a cleanup (Klein and Link 1970) was




considered but discarded because some chemical alteration by the procedure had




been reported (Ribick et al. 1982).  Silicic acid (Bidleman et al. 1978) was




repeatedly tested, however reproducibility was variable and we felt the




results couldn't be trusted.  Some of these tests are reported in Appendix A.




We finally settled on a simple treatment of the extracts with sulfuric acid,




followed by direct injection and analysis by electron capture gas chroma-




tography.








CHROMATOGRAPHIC ANALYSIS




     Analyses of the extracts involved concentration of each sample to 1 to




2 mL, acid treatment with an equal volume of concentrated sulfuric acid,




transfer of the organic phase, and then an initial prescreening of each sample




by packed column electron capture gas chromatography.  Based on these initial




prescreenings, the volume was adjusted for final qualitative and quantitative




analyses by the capillary GC.  For most of these final capillary injections,
                                       12

-------
a Varian 8000 auto-sampler was used.  The injection volume was 4 yL and the




solvent was petroleum ether or hexane.  The injection method was splitless




with a back flush delay of 0.75 minutes.  A toxaphene standard was usually




injected for each of four samples injected.  The operating conditions for the




capillary instrument were as follows:  the column was a (0.20 mm I.D. by 50 m




long) Hewlett Packard fused silica capillary column coated with SE-54, the




carrier gas was hydrogen flowing at a linear velocity of 35 cm/min, and




nitrogen was used as the makeup gas flowing at 30 mL/min.  The temperature




program was 100° to 240°C at the rate of l°C/min, and the other heated zones




were 220°C injector and 320°C detector.  Data handling for the capillary




instrument was carried out using a Perkin-Elmer Sigma 10 data system with a




basic programming upgrade.  To ensure proper data slicing, i.e., discrete area




slicing in small enough intervals to collect the capillary output, the Perkin




Elmer standard slicing option was overridden by forcing the instrument to




operate at its maximum slicing time of 0.13 sec/scan at 10 minute intervals.




This was determined by trial and error to give the best data treatment to the




entire spectrum of each 140-minute sample run.  The method for processing the




data was set to quantitate according to the external standard method.  The




retention times were calculated as relative retention times (RRT) to




octachloronaphthalene which was used as the reference peak.  DDE was used as a




reference peak for some of the samples (refer to Table 1).  These standards




were added to each sample just prior to GC analyses.  Relative retention time




of the reference peak was set to 10 so as to get an additional decimal place




listing from the relative retention time output of the Perkin Elmer data




system (i.e., the Sigma 10 only prints three figures after the decimal), and




achieve greater precision for peak matching.





                                        13

-------
     To select a standard which most consistently matched the peaks that were




being measured in the Greenville air samples, we examined three different




toxaphene formulations used in the Greenville area (Hercules BFC 90-100,




Central American 90-100, and  Drexel 616 Form Chem).  These were compared to




our EPA Research Triangle Park standard (Lot #B610).  From this study we de-




cided that the EPA standard gave the best matches (Appendix B).




     In order to establish an appropriate representation of toxaphene to be




used for comparison with samples, standards were screened and peaks were




chosen based on the following criteria.  Only peaks that were well resolved




and could be reproducibly identified between standard runs were considered.




In order to achieve reproducibility in peak identification, i.e., RRT match-




ing, while minimizing the inclusion of close eluting peaks within the peak




window, an RRT tolerance of +_ 0.008 was chosen.  Furthermore, it was




considered important that an even distribution of peaks over the total  elution




time for toxaphene be used.  Approximately 90 peaks were selected based on the




above criteria.  The selected peaks were then screened against expected




interferences.  For this study Aroclors 1242 and 1254 were especially




important in the Lake Michigan and St. Louis samples, and the pesticides DDT,




DDE, and chlordane were important interferences in Greenville.  Those peaks




which were matched with the various interfering components were removed from




the peak table.  During the course of our analyses, the number of peaks which




met all screening criteria for standards ranged from 26 to 60 (c.f. Table  1).




These peaks were then used to represent toxaphene for comparison with samples.




     Toxaphene identification in the samples was accomplished by screening




sample peaks for matches with the standard peak tables described above.




The criteria for peak matching in the samples was identical to those used  for





                                       14

-------
standard comparison.  However, those peaks that were matched in the  samples




were further screened for possible errors in baseline treatment, and unknown




interferences.  Peaks occurring in the sample that were disproportionately




high in area (relative to other matched peaks) were considered interfered with




and were excluded from quantitation.  This latter screening presupposes  that




the ratio of toxaphene peaks in the sample is similar to the standard.




Lacking proof of this, we selectively eliminated peaks only in the most




extreme case, e.g., when the (interfered) peaks accounted for greater than




approximately 40 percent of the sum of the area for all of the matched peaks.




     Quantitation of  toxaphene in the samples was based on the ratio of  the




sum of the areas for  peaks matched (and screened) in the sample to the sum of




the areas of the corresponding peaks in the standard.  This value was then




multiplied by the standard concentration and sample volume to determine  the




total ng of toxaphene.  The toxaphene concentration was the quotient of  total




nanogram of toxaphene determined to be in the sample divided by the  volume of




air (m-*) collected (Table 1).  Representative chromatograms of samples and




standards containing  toxaphene are shown in Figure 2.









QUALITY ASSURANCE




     Blanks were found to contain no recognizable toxaphene patterns.




However, some spurious peaks did match the relative retention times  for




toxaphene and upon quantitation averaged 23.1 ng.  Therefore, the limit  of




detection for the high volume samples was 0.06 ng/m^ and for the low volume




samples it was 0.6 ng/nH.  Linearity checks for electron capture response to




toxaphene were performed over the standard ranges of 118 to 444 ppb  and,




generally, linearity was good for the total mass of peaks (Figure 3).






                                       15

-------
     a
              wm
                                    ' wdftliMWiT
                                     M!m  Ife i! I
  Figure 2.   Capillary  chromatograms of toxaphene-containing air, rain
  and fish samples  and  EPA toxaphene standard.  The sculpin sample was
    analyzed on another project and is provided for comparison  of the
     atmospheric  data with biological residues,  a) Air sample from
   Beaver Island  (28 August to 31 August 1981) containing 0.054 ng/m^
     toxaphene;   b) Rain  sample from Beaver Island (28 September to
            2 October 1981) containing 31.58 ng/L toxaphene;
c) Sculpin composite sample from Lake Michigan (17 June 1982) containing
    0.718 ng/gm toxaphene; d) toxaphene standard (4 yL of  118 ng/mL).
       G/C conditions -50 m fused silica column coated with SE-54
        and temperature-programmed from 100 to 240° C at l°/min.
                                  16

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                                           17

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Consistent linearity was not observed for the individual peaks, however.  This




may bias our results as different assortments of selected peaks are used.




A thorough test for this was beyond the scope of this study.  However, we




observed the following:  In general, the ECD response of smaller, earlier




eluting peaks tended to exhibit greater linearity within the range of




concentrations tested than did larger, later eluting peaks.  In addition, the




intercepts of the linearity plots for the smaller peaks tended to be negative




while the intercepts for the larger peaks were generally positive.  One




conclusion from this treatment was that using a good spread of peaks over the




range of those possible would cancel out this opposing linearity, therefore




our peak selection procedure should have minimized this problem.




     Duplicates were run at Beaver Island and reasonable replicate performance




was observed, see Table 2.






                          TABLE  2.   DUPLICATE  RESULTS


Beaver Island
Sample Date
8/28
8/31
9/28

Toxaphene
Concentration
(ng/m3)
0.054 0.023
0.2335 0.2773
0.0237 0.0309

Relative %
Difference of
Duplicates
43
8
13
x = 21
Averaging the results for the three duplicate sets gave a value of  21  for  the




average relative percent differences of three duplicates.




     A performance test was conducted using standard  solutions of toxaphene




and Aroclor  1254 provided by the Grosse lie EPA laboratory in January  of  1982.
                                       18

-------
MODELING




     The atmospheric deposition of toxaphene into the Great Lakes is




speculated to be the result of transport from regions far removed from the




area.  To assess this claim, diagnostic modeling tools have been developed and




applied to the measured values of toxaphene for three of the sampling sites.




The diagnostic techniques used in this study take into account the potential




long-range transport of toxaphene and can include enroute processes of dry and




wet deposition, chemical transformation, and dispersion.  The areal




probability of contribution to the toxaphene levels at a receptor is




calculated in two ways.  In the first, the areal probability field resulting




from the ensemble of individual trajectories arriving at the receptor during




the hours of sampling is calculated.  This is the probability of contribution




due to "natural" phenomena.  It would represent the spatial distribution of




contribution if emissions were universally homogeneous.  In the second method,




the individual trajectory probabilities are weighted proportionally to the




resulting toxaphene concentrations.  If there is systematic transport of the




toxaphene to the receptor from a particular area or areas, the two fields will




be dissimilar.  On the other hand, if there is no clear "corridor" associated




with the transport of toxaphene, then there will be little difference between




the weighted and unweighted contribution probability fields.




     The assessment of potential long-range transport of atmospheric




contaminants requires an estimation of the trajectory of the air prior to




being sampled.  In this study, the model of Heffter (1980) was used to




calculate the upwind trajectories.  The model estimates the height of the




transporting layer by scanning temperature data from rawinsonde ascents ,




looking for stable layers 300 m or more above the surface.  The bottom of the
                                       19

-------
transport layer is defined as the top of the layer of surface-induced wind




shear.  Typical transport depths in the Midwest United States are about




1,600 m during the summer months.  Once the trajectory to the receptor has




been estimated, the dispersion of material along the route is estimated based




on the wind shear through the mixed-layer.  Estimates of the rate of




dispersion have been reported by Samson (1980), Samson and Moody (1980), and




Draxler and Taylor (1982).  In this work it is assumed that the dispersion of




the contribution probability is linearly proportional to time.  The area which




could have contributed to the concentration at the receptor is determined




through the integration of normally-distributed, two-dimensional "puffs"




growing upwind of the receptor.  Deposition of the contaminant en route to the




receptor will reduce the potential for far upwind sources to contribute to the




sample.  The reduction, probably due to dry deposition, has been expressed by




use of a dry deposition velocity, V
-------
to the measurement locations would affect the potential of upwind  source

regions to contribute, but little is known about wet deposition of  the

toxaphene.  Differential distributions of precipitation could have  an impact

upon even the relative difference in probability, but quantitative  estimates

of precipitation rates for 1981 are not yet available from the National

Climatic Center.  While this limits the interpretation of results,  the

comparison of weighted versus unweighted contribution fields still  provides  a

useful first test of the hypothesis that the toxaphene is being transported  to

the receptors from source fields in the southern United States.
                                             ,* ,



                            RESULTS AND DISCUSSION



     The concentrations of toxaphene measured in the air collected  at the  four

sampling sites are listed in Table 1.  The levels were highest in  Greenville,

Mississippi (average of 7.39 ng/rn-^ - monthly collections not included),

followed by St. Louis, Missouri (1.18 ng/rn-^), and lowest in Bridgman (0.35

ng/nH), and Beaver Island, Michigan (0.09 ng/rn^).  The listing for  peak

matching in Table 1 provides an estimate of the similarity of the material

measured to the standard.  These can also be calculated as percentage matches

which allows direct comparisons to be made between locations.  The  mean

percent matches for each of the sampled regions merging Beaver Island and

Bridgman for the Lake Michigan segment were as follows:  36% for Lake

Michigan, 38% for St. Louis, and 51% for Greenville.  One interpretation of

this might be that the toxaphene in Greenville is closer to the source than

the material measured in air at St. Louis or near Lake Michigan.  And that

distance from the source causes changes in the composition of the  toxaphene

mixture (often expressed as "weathering").  Another interpretation  might be

                                      21

-------
that the lower match percents are merely a function of the smaller amount of




material in the samples at the more northern sites.  Regression analyses on




the amount of toxaphene measured versus the percentage of peak matched with




each sample subset (Greenville, Bridgman, St. Louis, and Beaver Island),




however, were not found to be significant.  Therefore, the degree of




alteration of the toxaphene mixture does, in fact, appear to be related to the




distance from the likeliest source regions which we propose are in the




Southern United States.




     Table 1 also lists the total volume of air collected for each sample.




Regression analyses of this parameter versus the concentration measured were




carried out for each sample subset.  No significant correlations were found




for any of the high volume collections taken in the northern sampling sites.




However a positive correlation was found for the Greenville site, i.e., the




greater the air volume sampled, the lower the total nanogram amount.




Even when the monthly collections, which tended to underestimate the real




concentrations, were left out of the calculations, the correlations were still




significant.  This finding led to further tests to see if breakthrough of the




toxaphene could be observed on the low volume backup plugs.  Recall that the




Greenville sampling plugs were smaller than the Hi-Vol® plugs.  No toxaphene,




however, was found on the backup plugs, therefore breakthrough did not appear




to be occurring.  This was consistent with extensive tests of polyurethane




foam collection efficiency for trapping of toxaphene vapors (Rice et al. 1977,




Billings and Bidleman 1980).




     Since breakthrough was not occurring with the low-volume collectors,




there appears to be no obvious explanation for the low values found for the




monthly collections in Greenville.  Possibly, with these high volumes (90 to
                                      22

-------
200 m^ of air) and the relatively high levels of toxaphene being collected,




re-release of toxaphene from the collection plugs was occurring.  Other




factors which were also different for the monthly low-volume collection were




the lower air flow used, i.e., 2 to 4 L/min vs. 5 to 10 L/min for the short




duration low-vols, and also the length of time the samples were left out,  20




to 30 days versus 2 to 3 days.  Any one or all of these factors may have




contributed to the difference in results between the monthly collections and




the shorter interval Greenville collections.  Tests for collection efficiency




of toxaphene under low-volume/long duration sampling conditions would be




recommended if further work using this method is planned.  Comparison of the




low-volume collector (short duration) with simultaneous high-volume




collections were performed in a previous study (C. P. Rice and C. E. Olney,




unpublished results), and the two systems compared favorably.  Therefore,




we do not feel there is any problem in the short duration results.




     Filter retention of toxaphene appeared to be less than 5% of the total




measured toxaphene for the Hi-Vol® collections.  A qualification is needed




here, however, in that the error range for these measurements were relatively




high.  The peak matching percentage for most of the toxaphene identifications




on the filters were 15% or less, i.e. 4 to 5 peaks of the 26 to 40 possible.




Because of the low values for the filters and the high uncertainty connected




with these results, only the first plug analyses were used in reporting the




toxaphene amounts measured.




     Figures 4 and 5 present the results listed in Table 1 in graphical form.




It is apparent that for each of the locations an increase occurred in amount




of toxaphene from the first sample period in early August to early September,




whereupon a gradual decline in concentration was observed for the October and






                                       23

-------
              20 OH
            ro 10 0^
              200
                       n
                    8/1
                                  GREENVILLE
                                 n

                               9/1
                                   ST  LOUIS
              20-1
               10-
             o
             s
I
                                            n
            i   '•

            0/1

       BRIDGMAN
                                               1
                               9/1
                                         10/1
                                                    ll/l
  Figure 4.   Simultaneous determinations of toxaphene  in  air measured at
four sites lying  along a general south-to-north transect from Greenville,
Mississippi,  through St. Louis, Missouri,  and ending in the Lake  Michigan
  area (Bridgman and Beaver  Island,  Michigan).  The vertical axes are in
          log units and the horizontal  axes  are calendar dates.
                                     24

-------
   2.0-
ro
    1.0-
                               BEAVER  ISLAND
 O
 cn
 UJ
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 z
 o
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 LU

 Q_
O.I -
    .01-
                           j
                           II
           8/1
                           9/1               10/1
                              SAMPLING  DATE
I I/I
         Figure  5.  Toxaphene in air measured at Beaver Island,  Michigan,

         from 28 August to 4 October 1981.  Vertical axis is in  log units

                 and the horizontal axis is in calendar dates.
                                       25

-------
November sampling periods.  Table 3 presents these findings in average

concentrations for each of these discrete sampling periods.

     This trend for toxaphene levels in air observed in our data was similar

to the trend for relative levels of atmospheric/toxaphene observed by Arthur

et al. (1976) in the Mississippi Delta in 1972-1974.  In Arthur et al.'s

st'dy, the maximum average toxaphene occurred in August/ September periods:

1,540 ng/m3 - Aug. '72; 269 ng/m3 - Sept. '73; 903 ng/m3 - Aug. '74.  These

average concentrations were considerably higher than measured by us.  However,

toxaphene usage is reported to be much less now than in the early 1970s (Larry

Lane, Mississippi State University, Agricultural Experiment Station, Personal

Comm.).
         TABLE 3.  TREND IN TOXAPHENE CONCENTRATION AT SAMPLING SITES
                        FOR THE  SUMMER AND  FALL  OF  1981

Average toxaphene concentration by location (ng/m3)
Sampling
Interval
August
September
October
November
Beaver Island ,
Michigan

0.15
0.03

Bridgman,
Michigan
0.26
0.62
0.30
0.23
St. Louis,
Missouri
1.31
2.16
0.69
0.56
Greenville ,
Mississippi
6.61
11.40
6.04
2.64
     In looking at Figure 3, one might expect some similarities in concentration

patterns between the three locations, especially if an atmospheric link is

predicted.  For example, the first interval bears a close resemblance in general

pattern between St. Louis and Greenville.  There appears to be a tendency to

observe possible shifts by one sampling period of a high level of toxaphene

observed at one location to an appearance of this material as a high level in  a


                                      26

-------
more northerly location a few days later (notice such a connection  for  St.  Louis




to Bridgman for the first sampling period, Figure 4).  Keep in mind that  the




scale for the Bridgman figure is a factor of ten less than the two  other  sites




depicted.




     One rain sample was collected from Beaver Island, Michigan, while  air




measurements were being made from 28 September to 2 October 1981.   The  sample




contained 31.6 ng/L of toxaphene with  14 peaks matched out of 37 possible in  the




peak table.  Another rain sample collected on 1 April 1981, also from Beaver




Island, was found to contain 70.2 ng/L with 5 out of 37 peaks matched.









MODELING OF ATMOSPHERIC TRANSPORT




     One goal of this study was to use these data as a basis for proposing




some boundary limits for toxaphene transport and deposition to Lake Michigan.




We chose an atmospheric transport model to assist in these estimates.




     The "natural potential" for contribution to toxaphene concentrations at




the Bridgman, Michigan, site is shown in Figure 6.  This figure shows the




probability of contribution in units of 10~° km~^.  It is the area which  would




contribute to the concentration of toxaphene if emissions were homogeneous  and




constant over the grid.  The plot shows that the highest occurrence of  winds




during the sampling periods was from the southwest of the receptor.  Figure 7




shows the result of weighting each trajectory by the concentration measured at




the time of arrival.  It is assumed that each trajectory arriving through the




sample period contributed equally to the sample loading of toxaphene.   The




results indicate that the basic structure of the contribution field is  not




substantially varied from the spatial pattern found for the unweighted  case in




Figure 6.   The similarity of the two fields can be discerned only by







                                     27

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29

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calculating the difference between the weighted and unweighted fields as shown




in Figure 8.  This plot suggests that there is a slight spatial bias (or




corridor) for toxaphene, with higher concentrations associated with winds from




the south to southeast, but the magnitude of the difference in the weighted




and unweighted fields is small, being an order of magnitude lower than the




magnitude of the probability of contribution field (Fig. 6).




     Figures 9 and 10 show the unweighted and weighted fields, respectively,




for the receptor at St. Louis, Missouri, based on the 15 samples collected




there in 1981.  These two fields again appear to be relatively similar, but




the difference of the weighted and unweighted fields, plotted in Figure 11,




has a markedly higher amplitude than was apparent at the Bridgman, Michigan,




site.  Here the analyses suggest a more well-defined corridor of higher




concentrations from the south, supportive of the hypothesis that the toxaphene




was being transported from regions of application in the southern United




States.




     The unweighted probability field for Greenville, Mississippi, is plotted




in Figure 12.  The distribution of wind flow to the site on the days of




sampling is more isotropic here than at either Bridgman or St. Louis, as




indicated by the relative symmetry of the probability field about the




receptor.  The weighted probability field, shown in Figure 13, does not appear




to be dissimilar to the unweighted field, but its difference from Figure 12,




plotted as Figure 14, indicates that a relatively large bias is exhibited by




the data.  The corridor for higher concentrations of toxaphene at the




Greenville site is associated with winds originating along the Gulf Coast.




Winds from the north are systematically associated with lower than average




concentrations.
                                       30

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                The analysis of transport corridors for Beaver Island, Michigan samples


           was not conducted because only four samples were available for that site.


                It has been assumed that each trajectory during the sample period was


           equally responsible for the observed concentration.  However, without better


           temporal resolution in the sampling, it is difficult to assess the uncertainty


           inherent in this assumption.  For comparison, the transport of atmospheric


           trace elements is highly episodic.  The dry deposition of trace elements,


           assuming the process is proportional to the ambient concentration, is highest


           during specific episodes of roughly 3 or 4 days duration (cf. Husain and


           Samson 1980).  The significance of such episodic contribution could be lost in


           this analysis if the episode were split by two or more long-period samples.


           The diagnostic methodology developed for this study is designed to be employed


           with a larger data base.  The sample size available in this study limits the


           use of ensemble analyses.


                Nonetheless, the results of this diagnostic analysis of the measured

     /&
 *  . •*      toxaphene concentrations shows a consistent pattern. At all measurment

i>   •
\-y.t        locations the toxaphene corridor was associated with southerly winds.  The


           preferred corridors of transport of higher concentrations increased from


           northern to southern measurement sites, presumably in response to the larger


           range of concentrations in the south.  This analysis is not capable of proving


           which source region(s) contributed to the observed concentrations, in part


           because so little is known about the magnitude of the source strengths.


           However, the methodology developed for this analysis is capable of identifying


           the probable corridors of transport which deliver the material to the


           receptor.  The method is well suited for analysis of data which, because of


           low concentrations in the atmosphere, must be collected over long time periods




                                                 38

-------
(greater than a day).  With a sufficient number of samples, intra-period




fluctuations in contribution to the sample will be removed and meaningful




transport characteristics will be discerned.









ESTIMATES OF ATMOSPHERIC FLUX OF TOXAPHENE TO LAKE MICHIGAN




     For this estimate the concentration over Lake Michigan was used  as the




immediate source for input.  Our data provide a good estimate of this  amount




for August through November of 1981.  Using the formulations proposed  by




Eisenreich et al. (1981) for estimating atmospheric flux of trace  organics to




the Great Lakes, total atmospheric loading to Lake Michigan for 1981 was




estimated.  For wet and dry flux, the general equations presented  by




Eisenreich et al. (1981) were:







                         Fw = Cr/s • J • SA                                (1)




                         Fd = cv/P * Vd ' SA                               (2)






Fw and F^ are wet and dry deposition, respectively; Cr/s = concentration in




rain and snow; Cv/p = concentration in vapor and particulate; J =  annual




precipitation; V
-------
1/2 of this amount.  Therefore, as a whole lake estimate, these two

concentrations were averaged, i.e.,


                       [0.35 ng/m3 + 0.35/2 ng/m3] = 0.26 ng/m3.

                                   2


No direct observations were available for estimating a winter concentration

(December to May) and no observation of input as snow has ever been reported.

Therefore, to approximate what the air levels might have been, comparisons of

summer to winter levels of toxaphene determined for air in South Carolina

(Harder et al. 1980), and Bermuda (C. P. Rice, unpublished data) were

available.  These data indicated that approximately 2 to 4-fold decreases in

atmospheric levels in winter could occur.  Because of wind transport into Lake

Michigan during winter months, was expected to be dominated by northern cold

fronts, the lower estimate (1/4) was selected.  Therefore, the toxaphene

concentration estimated for the 6 winter months (December to May 1980-81)

preceding the data presented here was 0.26 ng/m3/4 or 0.065 ng/m3.  An average

yearly concentration for Lake Michigan air, northern and southern plus winter

and summer, was calculated as


                           0.26 + 0.065
                           	 = 0.16 ng/m3
                                2


This air concentration was next used to derive an expected yearly rain

concentration.  For this, a washout ratio was needed.  The washout ratio from

our one rain sample came out to 1,355
                                       40

-------
                         ng toxaphene/kg rain
                   WR  .	                               (3)

                         ng toxaphene/kg air



                         31 ng/kg rain (28 Sept-1 Oct)
                   WR  =	

                         0.027 ng/(m3 =1.18 kg) Air (28 Sept-1 Oct)



                   WR  =1,355



This greatly exceeded Bidleman's (Bidleman and Christensen 1979) highest


observed value for washout ratios calculated from rainfall input of toxaphene in


South Carolina (i.e., <16 to 861), and therefore appeared to be too high.


As a compromise we chose a range of 500 to 1,000 for the likely range of washout


ratio to be used in our calculations.  Carrying out the calculation, rain


concentrations were estimated to range from 68 to 136 ng/kg, e.g.,



                                        cone rain
                   500 to 1,000 = 	
                                  0.16 ng/(m3 = 1.18 kg)



                                = 68 to 136 ng toxaphene/kg rain





     Using these values in Eisenreich's formulation (Equation 1), the fol-


lowing was calculated:


Flux wet = Cr/s • J • SA     (68 ng/L)


         = (103 kg/m3)  (68 x 10"12 kg tox/kg rain) (0.74 m/yr) (5.9 x 1010 m2)


         = 2,969 kg tox/yr at a rain concentration of 68 ng toxaphene/kg rain


         = 5,938 kg tox/yr at a rain concentration of 136 ng toxaphene/kg rain
                                       41

-------
Dry Flux Calculation




     For this calculation, the deposition velocity of <0.12 - 0.24 cm/sec was




taken from literature values presented by Bidleman and Christensen (1979) and




Harder et al. (1982).  The calculation for a 0.12 cm/sec was as follows:




         Fd = Cv/p • Vd - SA




         Fd = (602 • 24 • 365 sec/yr) (0.16 x 10~12 kg/m3)




              (0.12 x 10~2 m/sec) (5.9 x 1010m2)




            = 357 kg toxaphene/yr @ Vd = 0.12 cm/sec




            = 715 kg toxaphene/yr @ Vd = 0.24 cm/sec




     Comparing the relative input from the two processes, wet deposition




appears to predominate, i.e., 3,000 to 6,000 kg/yr wet, versus 350 to 720




kg/yr for dry deposition.




     A total flux would be 3,360 to 6,720 kg/yr for toxaphene from all




atmospheric sources.  These are similar to the estimated total input for PCB




of 4,700 kg/yr for Lake Michigan (Murphy et al. 1982).  However, Murphy's




estimates indicated the largest input for PCBs are dry deposition processes,




while our results indicate that rainfall is the predominant vector for




toxaphene input.  The greater likelihood of rainfall deposition dominating for




toxaphene over other organochlorines (PCB, DDT, and chlordane) was also




observed by Harder et al. 1982.  It should finally be pointed out that the




above calculations are based on a very limited data set, especially for the




rainfall and dryfall estimates.  Thus, the flux values which are derived must




be considered speculative at this time.  However, recent analytical data on




residue levels in biota of the lakes suggest that the current levels of




toxaphene are indeed similar to those of the PCBs (Rice and Evans, in press).
                                      42

-------
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Arthur, R.D., J.D. Cain, and B.F. Barrentine.  1976.  Atmospheric levels of




     pesticides in the Mississippi Delta.  Bull. Environ.  Contain. Toxicol.




     15: 129-134.




Bidleman, T.F., and E.J. Christensen.   1979.  Atmospheric  removal processes




     for high molecular weight organochlorine compounds.   J. Geophys. Res. 84;




     7857-7862.




Bidleman, T.F., and C.E. Olney.  1974.  Chlorinated hydrocarbons in  the




     Sargasso Sea atmosphere and surface water.  Science 183:  516-518.




Bidleman, T.F., and C.E. Olney.  1975.  Long range transport of toxaphene




     insecticide in the western North Atlantic atmosphere.  Nature 257: 475.




Bidleman, T.F., J.R. Matthews, C.E. Olney, and C.P. Rice.   1978.  Separation




     of polychlorinated biphenyls, chlordane, and p,p'-DDT from toxaphene by




     silicic acid column chromatography.  J. Assoc. Offic.  Anal. Chem. 61:




     820-828.




Bidleman, T.F., E.J. Christensen, W.N.  Billings, and R. Leonard.  1981.




     Atmospheric transport of organochlorines in the North Atlantic.




     J. Marine Res. 39: 443-464.




Billings, W.N., and T.F. Bidleman.  1980.  Field comparison of polyurethane




     foam and Tenax-GC resin for high volume air sampling  of chlorinated




     hydrocarbons.  Env. Sci. Technol.  14: 679-683.




DeVault, D., R.J. Bowden, J.C. Clark, and J. Weishaar.  1982.  Results of




     contaminant analysis of fall run coho salmon, 1980.   Presented  at 25th




     Conference on Great Lakes Research, International Association for Great




     Lakes Research, Sault Ste. Marie,  Ontario.






                                      43

-------
Draxler, R.R., and A.D. Taylor.  1982.  Horizontal dispersion parameters for




     long-range transport models.  J. Appl. Meteor. 21: 367-372.




Eisenreich, S.J., B.B. Looney, and J.D. Thornton.  1981.  Airborne contami-




     nants in the Great Lakes ecosystem.  Environ. Sci. Technol.  15: 30-38.




Harder, H.W., E.J. Christensen, J.R. Matthews, and T.F. Bidleman.  1980.




     Rainfall input of toxaphene to a South Carolina estuary.  Estuaries 3:




     142-147.




Heffter, J.L.  1980.  Air Resources Laboratories Atmospheric Transport and




     Dispersion Model (ARL-ATAD).  NOAA Tech. Memo., ERL ARL-81.  17 pp.




Holmstead, R.L., S. Khalifa, and J.E. Casida.  1974.  Toxaphene composition




     analyzed by combined gas chromatography-chemical ionization mass spec-




     trometry.  J. Agric. Food Chem. 22(6): 939-944.




Husain, L., and P.J. Samson.  1980.  Long-range transport of trace elements.




     J. Geophys. Res. 84: 1237-1240.




Jansson, B., R. Vaz, G. Blomkist, S. Jensen, and M. Olsson.  1979.  Chlor-




     inated terpenes and chlordane components found in fish, guillemot and




     seal from Swedish waters.  Chemosphere 4: 181-190.




Klein, A. K., and J. D. Link.  1970.  Elimination of interferences in the




     determination of toxaphene residues.  J. Assoc. Official Anal. Chemists  53:




     524-529.




Korte, F. , I. Scheonert, and H. Parlar.   1979.  Toxaphene (camphechlor) ,




     a special report.  Internat. Union of Pure and Appl. Chem. 51: 1583-1601.




Murphy, T.J., G. Paolucci, A.W. Schinsky, M.L. Combs, and J.C. Pokojowczyk.




     1982.  Inputs of PCBs from the atmosphere to Lakes Huron and Michigan.




     Report of USEPA Project R-805325.  Duluth Environmental Research




     Laboratory.







                                      44

-------
Nash, R., M. Beall, Jr., and W. Harris.   1977.  Toxaphene  and  1,1,1  tri-




     chloro-2,2-bis (p-chlorophenyl) ethane  (DDT) losses from  cotton in an




     agroecosystem chamber.  J. Agric. &  Food Chem. 25(2):  336-341.




Pack, D.H., J.E. Lovelock, G. Cotton, and C. Curthoys.   1977.  Halocarbon




     behavior from a long time series.  Atmospheric Environment  11:  329-344.




Rappe, C., D.L. Stalling, M. Ribick, and  G.  Dubay.  1979.   Identification of




     Chlorinated "Toxaphene Like" Compounds  in Baltic  Seal  Fat and Lake




     Michigan Fish Extracts by CI-GC/MS., Paper 102, Pesticide Section  177th




     Nat. Meeting of the Amer. Chem. Soc., Honolulu, Hawaii.




Ribick, M.A., G.R. Dubay, J.D. Petty, D.L. Stalling, and C.J.  Schmitt.  1982.




     Toxaphene residues in fish: Identification, quantification,  and con-




     firmation at part per billion levels.   Environ. Sci.  Technol. 16(6): 310-




     318.




Rice, C.P., and M.S. Evans,  (in press).  Toxaphene in  the  Great  Lakes.




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     New York: John Wiley & Sons.




Rice, C.P., and C.E. Olney.  1978.  Air mass transport  of  toxaphene.




     Abstract 176th American Chemical Society National  Meeting,




     Environmental Chemistry Division.  Miami, Florida.




Rice, C.P., C.E. Olney, and T.F. Bidleman.   1977.  Use  of  polyurethane foam




     to collect trace amounts of chlorinated hydrocarbons  and  other  organics




     from air.  World Meteorological Organization Special  Environmental Report




     #10, WMO-No. 460.




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     Pesticides: transatlantic movements  in  the Northeast  trades.




     Science 159: 1233-1235.






                                      45

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Samson, P.J.  1980.  Trajectory analysis of summertime sulfate concentrations




     in the Northeastern United States.  J. Appl. Meteor. 19: 1382-1394.




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     Poll. Modeling. Amsterdam, in Air Pollution Modeling and its Application




     1^.  C.D. Wispelaere, Ed.  Plenum Press.  New York.  43-54.




Schmitt, C.J., J.L. Ludke, and D.F. Walsh.  1981.  Organochlorine residues




     in fish: National Pesticide Monitoring Program.  Pestic. Monit. J.




     14: 136-206.




Seba, D.B., and J.M. Prospero.  1971.  Pesticides in the lower atmosphere of




     the northern equatorial Atlantic Ocean.  Atmos. Environ. 5: 1043-1050.




Seiber, J.N., S.C. Madden, M.M. McChesney, and W.L. Wintertin.  1979.




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     residue behavior on leaves and in air, soil and sediments determined by




     capillary GC.  J. Agric. & Food Chem. 27(2): 284-291.




Slinn, W.G.N.  1982.  Estimates for the long-range transport of air pollu-




     tion.  Water, Air, and Soil Pollution 18: 45-64.




Wolff, G.T., P.J. Lioy, R.E. Meyers, R.T. Cederwall, G.D. Wight, R.E. Pasceri,




     and R.S. Taylor.  1977.  Anatomy of two ozone transport episodes in the




     Washington, D.C., to Boston, Mass., corridor.  Env. Sci. Technol.  11:




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Zell, M., and K. Ballschmiter.  1980.  Baseline studies of the global pollu-




     tion.  II.  Global occurrence of hexachlorobenzene (HCB) and polychloro-




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     Chem. 300: 387-402.
                                      46

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                                 APPENDIX A


              TESTS FOR SILICIC ACID FRACTIONATION OF TOXAPHENE
     In order to reduce the possibility of incorrect  identification of gas
chromatographic peaks which could co-elute with toxaphene, methods were
investigated which were designed to  selectively remove these interferences.
The most problematic interferences expected were PCBs.  Silicic acid

chromatography has been reported to  effectively separate toxaphene from PCBs
(Bidleman et al. 1978).


                                   METHODS
     The silicic acid method in its  complete form as  proposed by Bidleman

et al. (1978) was  first tested.  The water content of the original method was
modified to contain 2.8% water rather than 3.3%.  Also, the elution pattern

was changed slightly so that separation of PCBs from  DDT and chlordane was
optimized.  The elution pattern was  as follows:
            Solvent
          petroleum ether

Vol.
1- 10 mL
10- 40 mL

40-120 mL

20 mL


Fraction
1
2

3

4

Compounds
Expected
HCB
o>10% toxaphene,
PCBs, DDE
^30% toxaphene,
chlordane, DDT
60% toxaphene,
dieldrin, ODD
          dichloromethane
To maximize toxaphene recovery for this study, we recombined fractions 3 and
4.  Using this procedure recovery of toxaphene from column spikes was poor
(20%, see Table Al).  We then further modified the collection sequence by
                                      Al

-------
taking only 2 fractions, i.e. 0 to 40 mL for PCB, HCB, and DDE and then a




20 tnL methylene chloride sweep to secure the bulk of the toxaphene along with




DDT, ODD, dieldrin, and chlordanes (Table Al, samples 2 and 3).  With the 2




fraction procedure, recovery was improved but only marginally acceptable, i.e.




76 and 98%.







                TABLE  Al.   SILICIC ACID  RECOVERY  OF  TOXAPHENE

Method Used
4-Fract ion
(F3 + F4 combined)
2-Fraction
(20 mL DLM)
2-Fraction
(20 mL DCM)
# of Peaks
Matched
12/31
29/33
21/33
Total Area Units
Spike Recovered Percentage
Standard Standard Recovered
11.795 2.37 20.1
12.23 9.33 76.3
8.24 8.13 98.0
     Based on these results, we decided that the fractionation procedures was




not acceptable because recovery losses were too great.  Such losses could not




be risked, especially for the low level samples from Bridgman and Beaver




Island.  Furthermore, funds were not available to carry out these labor




intensive procedures on the large number of samples generated during this




study.  Qualitatively, however, the method was a valuable confirmation tool.




We applied the two fraction silicic acid method to one of the Bridgraan air




samples.  In Figure Al, the unfractionated air sample can be compared to the




first 40 mL eluate of the fractionated sample (the PCB fraction).  An Aroclor
                                      A2

-------
A3

-------
1254 standard is also included in this figure as a representative PCBs for




comparison with the fractionated sample.   In Figure A2, the second fraction




(toxaphene fraction) is shown along with the unfractionated air sample and a




fractionated toxaphene standard.




     It is clear that most of the peaks appearing in the unfractionated sample




were eluted in the first fraction and many of them matched the PCB standard.




This obviously reduced the potential for interference occurring in the second




fraction (i.e., toxaphene fraction).  Furthermore, the chromatograms of the




fractionated toxaphene standard and the toxaphene fraction of the air sample




can be compared visually and they do bear some similarities.  (it is reassur-




ing to get a visual impression that the matches are real and not just blindly




trusting the data system to do peak matching.)  Figure A3 has been included to




indicate the relative distribution of peaks used for peak matching.




     The toxaphene concentration calculated for the Bridgman air sample using




unfractionated material, which was the general procedure adopted throughout




this study, was 0.665 ng/ra^.  The concentration calculated using the




fractionated sample and fractionated standard was 0.582 ng/m .  Therefore, the




two methods showed good agreement.  Furthermore, the peak matching for the




unfractionated sample was 14 of 41 possible (34.1%), and for the fractionated




sample it was 12 of 31 (39%).  Therefore, removing the interferences did




improve the matching as it should have.  Another advantage of the fractionated




method is that since PCBs are removed by the fractionation procedure, the peak




selection criteria used for standards could have been altered so as to include




peaks previously excluded from the peak table due to interferences with PCBs.




This would have further expanded the peak table used for peak matching arid




most likely further improved the basis for toxaphene quantitation.
                                      A4

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                       APPENDIX B










LETTER TO HOUSTON WELLS, WELLS LABORATORIES, DESCRIBING




            STUDY OF TOXAPHENE FORMULATIONS




            USED IN GREENVILLE, MISSISSIPPI
                           Bl

-------
Mr. R. Houston Wells
Wells Laboratories
RT 2 Box 714
Wilmont Rd.
Greenville, MS   38701
Dear Mr. Wells:

    Enclosed you will find tabulated the results of our analytical comparison
between four sources of toxaphene and two air samples taken in the Greenville
area:
                        .
    Toxaphene sources: '
         - U.S. EPA Toxaphene Reference Standard
         - Hercules l&C 90-100
         - Central America 90-100
         - Drexel 616 form chem.

    Samples :
         - 3011-2 collected 9/1/81  to 9/29/81 Greenville, MS (185 m3 of
           air)
         - 3018-2 collected 11/2/81 to 11/5/81 Greenville, MS (32_ m3 of
           air)

Our comparisons were based on total peak matches (table 1), distribution of the
matched peaks throughout the chromatogram (table 2) and the relative abundance,
in terms of Area percent, for peaks within prescribed intervals throughout the
chromatogram( table 3).  Seventy-six peaks were chosen to represent toxaphene for
our comparisons based on their relative abundance and non-interference with PCBs
and other pesticides.  Peak tables were constructed for each of the toxaphene
sources using our previously analyzed EPA toxaphene standard.  The analysis was
performed on a Varian 3700 Gas-liquid chromatograph equipped with a Hewlett
Packard 50 m. , fused silica, SE-54 capillary column and electron capture
detection.  Runs were temperature programmed from 100 °C to 245 °C at 1°C per
minute.  Injector and detector temperatures were 270°C and 320°C respectively.

    The primary purpose of this comparison was to select a toxphene standard
that best matched our samples.  For both total matches (table 1) and
distribution of those matches (table 2), the U.S. EPA toxaphene standard (tox.
std.) showed the greatest consistency between samples.  Greater than 50% of the
peaks were matched, for both samples, at a tolerance of 0.004 e.g. relative
retention time 40.004.  Those peaks that were matched appeared to be evenly
distributed throughout the chromatogram as well.  However, in terms of
composition, greater than 50% of the total peak area was represented within the
first two intervals (peaks 1 through 20, table 3) within which only about 25% of
the matched peaks occured.

    We were also interested in similarities between the four toxaphene sources.
Surprisingly, the peak matches between sources were relatively poor.  Best
matches occured between tox. std. and Central America (53 matched peaks) and
between Hercules and Drexel (58 and 64 matched peaks), (table 1).  Differences
between sources were also evident in the relative amount of material occuring


                                      B2

-------
within the various peak intervals (table 3).  Common to all sources however, was
the relatively sparse abundance of material in the last two peak intervals.

    Based on the aforementioned results, we feel that the U.S. EPA Reference
Standard is best suited for analyzing samples collected in the Greenville area.
We plan on continuing its use as our laboratory standard for future analysis.
                                       Singer
P.S.  Notice that for sample 3018-2 in table 2 the highest peak match was for
the Central American standard (perhaps this indicates a wind pattern link to a
user of this specific brand during this sampling.)  This was a short sampling
interval and could be more source specific than sample 3011 which was a 28 day
integrated sample.  Table 3 does show a similarity between Hercules and the
Toxaphene standard at least in relative percentage of peak areas represented by
each 10 peak interval.  The Drexel does appear to lack area for the later peaks
in this comparison (this may be construed as Drexel having less persistence
potential since these later peaks have heavier molecular weights and will be
less volatile).  Notice that from our air samples the heavier peaks were also
lacking, thus confirming that the more volatile early GC eluters are enriched in
the air as they should be due to their greater volatility.  The Central American
standard appears to be a good retention time match to our Toxaphene reference
standard e.g. table 1 with 53 for toxaphene compared with Central America and 53
with Central America compared to toxaphene.  Also, it appears to have a similar
percentage area distribution over the 8-10 peak area intervals as was observed
for the toxaphene and Hercules standards.
                                     B3

-------
Table 1.  Number of Peak matches between standards and two Greenville samples
(3011-2 and 3018-2) at two tolerance levels.  Total number of peaks chosen  for
comparison • 76.
                                     Standards Used for Comparison
Tolerance - 0.004
Tox. Std.
Hercules
Central
America
Drexel
3011-2
3018-2
Tox. Std.
(76)*
34

53
41
40
40
                                    Hercules
                                        35
                                        (76)*
                                        35
                                        58
                                        33
                                        21
                                          Central
                                          America
                                             53
                                             31
                                             (76)*
                                             32
                                             25
                                             43
                                            Drexel
                                              45
                                              64
                                              37
                                              (76)*
                                              32
                                              26
Tolerance
      Tox.
      Hercules
      Central
      America
      Drexel
      3011-2
      3018-2
 0.002
Std.
(76)*
10

31
19
26
23
11
(76)*

17
47
13
11
27
15

(76)*
12
10
30
19
50

15
(76)*
24
10
*  Each peak table was adjusted to match 76 peaks when compared against  itself
                                      B4

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Table 2.  Numbers of peaks matched between two Greenville samples and four
standards, peak intervals of 10 peaks per interval.  Tolerance « 0.004.
                   Numbers of Peak Matches Within the Specified Peak Range.

Sample   Standard   Total 1-10  11-20  21-30  31-40  41-50  51-60 61-70 71-76
                                                              363
3011-2   Hercules    33    3      4      3      3      8      552

                                                              2     3     1
                                                              552
         Tox. Std.   40    7      5      7      5      5      452
3018-2   Hercules    21    7      6      2      2      0      1     1     2
         Central
         America     43    6      3      6      7      9      570
         Drexel      27    3      5      4      6      5      1     1     1
         Total
Standard
Tox. Std.
Hercules
Central
America
Drexel
Total
Total
41
33
25
32
1-10
5
3
4
0
11-20
5
4
3
4
21-30
7
3
8
6
31-40
7
3
4
5
41-50
4
8
0
5
                                      B5

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Table 3.  Percentage of Total Peak area within Peak intervals.   Tolerance
0.004.

Tox. Std.
Hercules
Central
America
Drexel
*3011-2
*3018-2
1-10
17.38
12.55
16.22
19.70
19,20
12.47
11-20
16.30
13.27
7.47
14.04
43.38
38.61
21-30
12.57
15.39
12.22
19.29
9.20
12.04
31-40
14.13
11.74
15.39
11.75
15.93
11.96
41-50
11.77
15.88
18.02
14.88
3.62
13.91
51-60
16.49
18.78
15.85
11.50
5.04
7.10
61-70
9.72
10.16
13.16
5.49
3.22
3.63
71-76
1.64
2.22
1.67
3.34
0.42
0.28
     *Greenville samples - Identified using EPA Toxaphene Reference Standard
                                     B6

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Table 4.  Average Retention times and Relative Retention times (RRT x 10) for
peaks used on upper and lower limits of peak intervals referred to in tables 2
and 3.  Reference peak was DDE (RT   70.70 min.)

Peak
Number
1
10
11
20
21
30
31
40
41
50
51
60
61
70
71
76
Retention
Time (min)
44.53
56.36
57.24
67.99
68.36
74.30
70.44
77.86
78.46
85.56
85.93
90.94
91.06
98.67
99.51
100.37
Relative Retention
Time (RRT x
6.30
7.972
8.100
9.617
9.670
10.509
10.533
11.014
11.098
12.103
12.154
12.864
12.884
13.958
14.076
15.048
10)
















                                      B7

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