RISK ASSESSMENT, MANAGEMENT, COMMUNICATION A GUIDE TO SELECTED SOURCES VOLUME 5, NUMBERS 1 - 2 Office of Pollution Prevention & Toxics Library U.S. Environmental Protection Agency November 1994 Compiled by Geff King, Reference Librarian LABAT-ANDERSON Incorporated Contract 68-W4-0028 Delivery Order Number 500 Deliverable #6 U.S. Environmental Protection Agency Region 5, Library (PL-12J) 77 West Jackson Boulevard, 12th Floor Chicago, IL 60604-3590 ------- CONTENTS INTRODUCTION , i DISCLAIMER iii THE EPA LIBRARY NETWORK v RISK ASSESSMENT 1 GENERAL PERSPECTIVE 3 ASSESSMENT GUIDELINES 14 LEGAL ASPECTS 24 METHODS OF ESTIMATING RISK 27 HEALTH RISKS 45 GENERAL 45 CANCER 51 GENOTOXICITY AND REPRODUCTIVE EFFECTS 54 HUMAN AND ENVIRONMENTAL EXPOSURE 58 CHEMICAL SPECIFIC RISK ASSESSMENT 64 HAZARDOUS WASTE 84 ECOLOGICAL RISK 104 RISK MANAGEMENT 118 GENERAL PERSPECTIVE 120 RISK MANAGEMENT GUIDELINES AND POLICY 126 LEGAL ASPECTS 139 CHEMICAL SPECIFIC RISK MANAGEMENT 142 HAZARDOUS WASTE 148 ECONOMIC ANALYSIS 157 CORPORATE RISK MANAGEMENT 159 RISK COMMUNICATION 164 , INFORMING THE DECISION-MAKER 165 r INFORMING THE PUBLIC 169 INFORMING THE WORKER 171 BIBLIOGRAPHIES AND OTHER SOURCES 172 TITLE INDEX 175 ------- This page intentionally left blank. ------- INTRODUCTION This issue of Risk Assessment. Management, and Communication: A Guide to Selected Sources is the eleventh update in EPA's series of risk management bibliographies. References were gathered from the environmental, medical, and scientific literature included in the following DIALOG databases: Cambridge Scientific Collection (Pollution Abstracts), Conference Papers Index, Enviroline, Ei COMPENDEX, Legal Resource Index, Life Sciences Collection, and NLM's TOXLINE and MEDLINE. These citations cover documents added to those collections during the period from July 1992 to September 1994. Like its predecessors, this document is subdivided into Risk Assessment, Risk Management, and Risk Communication. The Table of Contents lists further divisions of each of these categories. Citations are arranged alphabetically by title, with the exception of the chemical specific references. These citations are grouped alphabetically by chemical name. Abstracts in this guide have been shortened or eliminated if the content of the article is adequately reflected in the title. The original Guide appeared in March 1987 and was followed by quarterly updates. These earlier updates constitute Volume 1 of the current semiannual series. *Guide: PB87-185500 1st Update: PB87-203402/AS 2nd Update: PB88-100102 3rd Update: PB88-128178 Volume 2, No. 1: PB89-210596 Volume 2, No. 2: PB89-189641 Volume 3, No. 1: PB90-237116 Volume 3, No. 2: PB90-282508 Volume 4, No. 1: PB92-114412/AS Volume 4, No. 2: PB92-238518/XAB *These five issues constitute Volume 1 of the current series. ------- This page intentionally left blank. ------- DISCLAIMER This issue of Risk Assessment. Management, and Communication: A Guide to Selected Sources has been prepared and reviewed by the Environmental Protection Agency (EPA). Due to the rapidly expanding field of risk information, EPA cannot guarantee that all relevant sources are cited. Publication does not signify that the contents reflect the views of EPA or that EPA endorses the coverage and scope of the subject matter as comprehensive, complete and appropriate. Copyright clearance for reproduction of these citations has been obtained in accordance with the ERA (Electronic Redistribution and Archiving) service offered by Dialog Information Services, Inc. for this purpose. To the best of our knowledge and belief, this Bibliography is in compliance with all guidelines and terms set forth by ERA, Dialog Information Services, and the individual database producers. This Bibliography is intended by EPA for INTERNAL USE ONLY by its staff and authorized contractors. ------- This page intentionally left blank. ------- THE EPA LIBRARY NETWORK The EPA Library Network can assist EPA staff members and EPA contractors in obtaining materials cited in the bibliography. Reference copies of the original Guide and subsequent issues are available through NTIS at the following address: National Technical Information Service 5285 Port Royal Road Springfield, Virginia 22161 (703) 487-4650 1-800-336-4700 (outside Washington, DC area) Any questions or comments concerning Risk Assessment. Management. Communication: A Guide to Selected Sources may be sent to: Risk Management Bibliographies U.S. Environmental Protection Agency Office of Pollution Prevention & Toxics OPPT Library (7407) 401 M Street, S.W. Room B606, NE Mall Washington, DC 20460 Email LIBRARY-TSCA@EPAMAIL.EPA.GOV ------- This page intentionally left blank. ------- RISK ASSESSMENT IS THE SCIENTIFIC PROCESS THAT EVALUATES THE POTENTIAL FOR OCCURRENCES OF ADVERSE EFFECT ------- This page intentionally left blank. ------- GENERAL PERSPECTIVE - includes: cross media approach, de minimis risk, and uncertainty in assessment Acceptable risk: a conceptual proposal Fischhoff, Baruch Risk: Health, Safety & Environment 5 n1 1-28 Wntr, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Assessing Risk: Toxicity in Perspective Williams, Cris TERRA, Tallahassee, FL Environ Prot Aug 93 v4, n8, p12(6) Language: English journal article 1 photo(s); 7 reference(s) Risk assessment is an integral component in the process of determining which chemicals should be subject to which regulations. Assessments may be qualitative or quantatative in nature. EPA has mandated risk assessments in the prioritization of Superfund site cleanups, and has developed guidelines for the incorporation of risk assessment in the remedial investigation/feasibility study for each site. According to these guidelines, the basic components of risk assessment are data collection and analysis, exposure evaluation, toxicity evaluation, and risk characterization. These guidelines are expected to evolve as the inexact science of risk assessment changes. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Building our nation's GIS treasure chest: The environmental risk assessment process as a catalyst to growth Bennett, M.J.; Buonicore, A.J. Environmental Data Resources, Southport, CT NAEP 18th Annual Conference, Raleigh, NC (USA), 24-26 May 1993 National Association of Environmental Professionals (NAEP) NAEP, PO Box 9400, Washington, DC 20016, USA; Telephone: (301) 229-7171, Abstracts, The Environmental Professional, ISSN: 0191-5398, Volume 15 Number 1 Supplement 1993; Proceedings Poster Paper No. 16 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 3 RISK ASSESSMENT ------- Cleaner Water, But Not Clean Enough Foran, Jeffery A. (Risk Science Institute, Washington, DC); Adler, Robert W. (Natural Resource Defense Council, Washington, DC) Issues Sci Technol Winter 93-94 1qr v10, n2, p33(7) Language: English Full text available from Congressional Information Service. journal article 12 reference(s) Despite the good intentions of the 1972 Clean Water Act (CWA) and its subsequent amendments, many sources of toxic pollutants are not being controlled. Ongoing research efforts have indicated that water pollutants are increasingly responsible for damage to wildlife and to human health. Failure to achieve the goals of the CWA stems from the two approaches instigated to control toxic substances discharged to surface waters: the mandated use of specific treatment technology for discharges from point sources of pollution, under which the designated technology may not be adequate; and water-quality-based approaches that requires EPA and the states to set maximum allowable concentrations of toxic pollutants in surface waters, which are supposed to pose no threats to human health or the environment, but are often based on questionable concepts of risk assessment. Ultimately, the most effective way to reduce the discharge of a toxic pollutant into surface waters is to reduce the use of the specific chemical or its precursor. This could be accomplished in two ways: technology- and water-quality-based controls could be adjusted toward zero-discharge criteria; and new requirements could be added to the CWA to promote pollution prevention by government and private parties. This becomes especially crucial when dealing with nonpoint pollution sources. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Developmental and reproductive toxicology: Ensuring the quality of data used for risk assessment Harris, S.B. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. RISK ASSESSMENT 4 ------- Environmental Equity and the Environmental Professional Harding, Anna K. (Oregon State Univ, Corvallis); Holdren, Jr. George R. (BatteUe Pacific Northwest Labs, Richland, WA) Environ Sci Technol Oct 93 V27, n10, p 1990(4) Language: English journal article 1 drawing(s); 23 reference(s) Consideration of environmental equity issues is emerging as a component of overall impact and risk assessment. The politics of waste disposal are argued to have given rise to the environmental equity issue. Upper class or white neighborhoods have exercised enough clout to prevent the local siting of hazardous waste facilities, which has resulted in the practice of siting such facilities in predominantly lower income, black areas. To guard against such preferential exposure to hazardous wastes, EPA and other federal and state agencies are urged to integrated environmental equity considerations into comparative risk assessment and other activities. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Environmental risk assessment Ward, Catherine M. Banking Law Journal 110 n3 204-215 May-June, 1993 LRI File 150 Environmental risk assessment: the divergent methodologies of economists, lawyers and scientists Stewart, Alan JOURNAL NAME: Environmental and Planning Law Journal 10 n1 10-18 Feb, 1993 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. EPA Publishes List of Substances, Thresholds Subject to Chemical Accident Prevention Rules Occup Saf Health Report-BNA Feb 2, 94 v23, n35, p1028(26) Language: English Full text available from Congressional Information Service. 4 table(s) EPA published a rule on Jan 31, 1994, requiring all companies that developed chemical process safety programs to meet OSHA requirements to 5 RISK ASSESSMENT ------- modify and enhance their efforts. The rule includes a complete list of the toxic chemicals that are paired to risk management planning requirements as established under the Clean Air Act. The substances on the list were isolated for the potential threats they pose to public health and the environment. A wide range of chemicals are covered by the ruling, including 77 acutely toxic chemicals, 63 flammable gases and liquids, and specific explosive compounds. The regulations will affect approximately 118,000 facilities, including public drinking water plants and waste treatment sites. A petition process for adding new chemicals to the list was incorporated into the measure. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. EPA's research to improve health risk assessments (RIHRA) program: Overview and water-related research Vandenberg, John J.; Fowle, John R. Ill; Zenick, Harold US Environmental Protection Agency, Research Triangle Park, NC, USA Proceedings of the 1991 AWWA Annual Conference, Philadelphia, PA, USA, Jun 23-27, 1991 Language: English Federal law requires the Environmental Protection Agency (EPA) to assess drinking water risks and to set standards to insure a safe drinking water supply. Given limited data, risk assessors rely on high dose experimental data, results from occupational health studies, and other data sets (e.g. in vitro tests) to make predictions about health outcomes. A variety of assumptions and extrapolations must be used to estimate from the results of these studies the likelihood of adverse health effects associated with a lifetime of water consumption. In recognition that the uncertainties in risk assessment may result in economic burdens (i.e. from over regulation) or inadequate public safety (i.e. from under regulation), EPA has established th6 Research to Improve Health Risk Assessments (RIHRA) program to resolve some of the major health risk assessment issues. This paper presents an overview of the RIHRA program and several examples of health research applicable to drinking water issues. 5 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. RISK ASSESSMENT ------- Experimentalist's look at risk assessment Furst, A. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Health risk assessments: a critical scientific technique for environmental regulators and litigators Broiles, Steven A. Los Angeles Lawyer 17 n1 34(12) March, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All its. reserv. Historical re-evaluation of a risk assessment Anderson, P.N., URS Consultants 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-RA-116A.01 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Impact of Data Gaps in EPA's Regional Comparative Risk Projects Day, Rosalie R. EPA, Chicago, IL Comparative Environ Risk Assessment (Lewis) 1993 p237(10) Language: English Full text available from Congressional Information Service. book chapter All EPA regional offices have completed risk assessments of key environmental problem areas as a basis for the prioritization of resources. Risks to both the environment and to human health are evaluated semiquantitatively. Regions reported inadequate access to data as well as time and resource constraints in accessing available data. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. 7 RISK ASSESSMENT ------- Incorporating risk assessment into the senior process design course. Barbari, T.A.; Marguies, T.S. Johns Hopkins Univ. Baltimore, MD, USA American Institute of Chemical Engineers 1993 Annual Meeting, Saint Louis, MO (USA), 7-12 November 1993 American Institute of Chemical Engineers AlChE Publications Dept.345 E. 47th Street New York, NY 10017, Individual Papers Paper No. 201 b Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Not by risk alone: reforming EPA research priorities Shifrin, Robin Yale Law Journal 102 n2 547-575 Nov, 1992 LRIFile 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. OSWER Environmental Justice Task Force Draft Final Report Executive Summary EPA Report OSWER 9200.3-16-1 DRAFT Apr 25, 94 (20) Language: English Full text available from Congressional Information Service. An EPA task force addressed environmental justice issues specific to waste management programs. Concerns that minority and low-income populations may bear disproportionately high and adverse human health and environmental effects from pollution were analyzed, and recommendations to ensure environmental protection for all population segments were formulated. Major recommendations presented focus on guidelines for environmental justice, Title VI of the Civil Rights Act, cumulative risk, federal interagency cooperation, economic redevelopment, and outreach, communications, and partnerships. Program-specific recommendations address siting, permitting, public involvement, and corrective action under RCRA, site and risk assessment in the Superfund program, and chemical emergency preparedness and prevention. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 8 ------- Pesticide Use Trends and Issues in the United States Osteen, Craig USDA, Washington, DC The Pesticide Question: Environ, Economics & Ethics (Chapman & Hall) 1993 p307(30) Language: English book chapter 8 graph(s); 58 reference(s); 10 table(s) The dramatic increase in pesticide use between the 1940s and the early 1980s is attributed to the increased use of agricultural chemicals, particularly herbicides, on major crops. Pesticide regulation has altered the mix of chemicals but not overall usage. Similarly, agricultural production rose 2.2 times, which prompted many farmers to hold to the notion that the high levels of chemical inputs were justified. Nevertheless, higher pesticide use has not assured control of all pest problems; the environmental consequences have been daunting. In addition, EPA has been criticized for taking a pesticide-by-pesticide approach to assessing costs and benefits. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Recognizing the limits of risk assessment Brown, D.A. Pennsylvania Dep. Environ. Resour. ENVIRON. PROF VOL. 14, NO. 3 pp. 185-186 1992 Language: ENGLISH Presently, the United States Environmental Protection Agency is using risk assessment procedures in environmental programs to set environmental priorities, standards, and clean-up levels. At the Earth Summit in Rio ^le Janeiro last June, the nations of the world adopted Agenda 21, which urged the use of risk assessment procedures in hazardous and nuclear waste decisions. In a short time, risk assessment procedures have become a very important tool of environmental managers throughout the world. However, managers using risk assessment procedures often are unaware of important limitations of risk-based decisionmaking. DIALOG(R)File 41 :Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RISK ASSESSMENT ------- Risk assessment in the Environmental Protection Agency (EPA) Abernathy, C.O. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Risk assessment: good for health? van de Wiel JA, Passchier W Health Council of The Netherlands, The Hague. REVIEW ARTICLE: 2 REFS. Toxicol Lett 1994 Jun;72(1-3):237-42 Language: English Risk assessment is a scientific endeavour on which risk management can be based and policy priorities can be set. Of prime importance is the choice of risk attributes and the health indicators to focus upon. Problem ranking and priority setting depend strongly on that choice. In the current risk policy of The Netherlands' Ministry of the Environment 'individual risk' is defined as the probability of dying due to one year's exposure to a certain agent or activity. If this approach is applied to the indoor environment, strong mitigation measures should be taken concerning N02, radon and paniculate matter to improve the percentage of 'healthy homes'. However, risk is*more than the chance to die. Therefore some more parameters should be used to characterize the indoor environment, like chemical and biological mixtures from outside and inside and activities of inhabitants. Important health indicators like irreversible/reversible physiological effects and nuisance should be taken into account. Risk has to tell us about the possibility of health damage, about the nature of health damage and about the uncertainty in both. MEDLINE Role of Comparative Risk Analysis Cleland-Hamnett, Wendy EPA, Washington, DC EPA J Jan-Mar 93 v19, n1, p18(6) Language: English Full text available from Congressional Information Service. journal article 3 photo(s) RISK ASSESSMENT 10 ------- Comparative risk analysis methods help EPA researchers comprehend the relative risk of various problems and narrow focus to the most important ones. However, a more participatory model of prioritization based on a system of inputs broader than was envisioned in the past is desirable. Guiding principles to achieving this model promote incorporating varied expertise in the risk assessment process from the earliest stage and the realization of more realistic risk characterizations. A foundation of credible risk assessment rests on basic research and state-of-the-art environmental data. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Science and judgment in risk assessment NATIONAL ACADEMY PRESS, WASHINGTON, DC 20418 (USA) 1994 Language: ENGLISH Concerns over air and its contamination by toxic pollution have led to a body of legislation about clean air. The most recent of these pieces of legislation is the Clean Air Act Amendments of 1990. As part of that legislation, the Congress directed the administrator of the Environmental Protection Agency (EPA) to engage the National Academy of Sciences (NAS) in a review of the methods that EPA uses to ensure that Americans have appropriately clean air. Congress's charge to the National Research Council (NRC) can be summarized in a short set of questions: 1. Given that quantitative risk assessment is essential for EPA's implementation of the Clean Air Act, is EPA conducting risk assessments in the best possible manner? 2. Has EPA developed mechanisms for keeping its risk-assessment procedures current in the face of new developments in science? 3. Are adequate data being collected to permit EPA to carry out its mandate? 4. What, if anything, should be done to improve EPA's development and use of risk assessments? This report attempts to address these questions and to provide advice to enable EPA to carry out the mandates of the Clean Air Act and to satisfy Congress's concerns about the implementation of the act and its 1990 amendments. The elements to be studied by the committee included "the techniques used for estimating and describing the carcinogenic potency to humans of hazardous air pollutants, as well as methods for estimating exposure to these materials." The legislation instructed NAS to "evaluate and report on the methodology for assessing the risk of adverse health effects" for hazardous air pollutants. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. 11 RISK ASSESSMENT ------- Toxicology and risk assessment Craigmill, A.L. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. TSCA Interagency Testing Committee, 1977 to 1992: Creation, Structure, Functions and Contributions Walker, John D. EPA, Washington, DC ASTM Environ Toxicol & Risk Assess: Aquat, Plant & Terrestrial Syrnp, Pittsburgh, PA Apr 26-30, 92 p451(59) Language: English Full text available from Congressional Information Service. • conf paper 3 diagram(s); 5 graph(s); 41 reference(s); 6 table(s) The Interagency Testing Committee (ITC), an independent advisory committee to EPA, is charged with establishing the TSCA Section 4() Priority Testing List and revising the latter every six months. ITC also identifies and coordinates federal sector data needs for chemicals on the Priority Testing List and designates high priority chemicals to EPA for testing under the Act. During 1977-92, ITC designated 106 chemicals, 3454 tests, and 20 chemical groups for priority testing consideration by EPA. Contributions to chemical testing realized by the recommendations and efforts of ITC are reviewed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. TSCA: the Sleeping Giant Is Stirring Hayes, David J. Latham & Watkins, Washington, DC Am Bar Assoc Environ Law Manual 1992 p362(10) Language: English book chapter The Toxic Substances Control Act {TSCA) contains strong incentives for EPA to gather information on chemical usage and exposure in the workplace. The act requires that any manufacturer, processor, or distributor in commerce of a chemical substance or mixture must report RISK ASSESSMENT 12 ------- to EPA the incidences of substantial risk, disclose manufacturing and processing information, conduct extensive health and safety studies, and keep detailed and accurate records. Applying the TSCA's information-gathering tools to distributors of chemicals in commerce has substantially broadened EPA's net. EPA's expansive interpretation of TSCA language appears to encompass the traditional use of chemicals, and it also threatens to draw in large numbers of companies that neither manufacture nor process chemicals in the traditional sense, but simply use chemicals as part of a nonchemical manufacturing process. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. White House Postpones Risk Assessment Reform EPA Watch Aug 15 92 v1, n10, p1(2) Language: English Full text available from Congressional Information Service. newsletter article The White House has decided to postpone making a decision regarding a proposed overhaul of the government's policy regarding environmental risk assessments until after the elections in 1992. The move was considered a political decision, made to avoid possible controversy during an election year, the vice presidential opposition candidate Al Gore representing environmental concerns. Details of the proposed overhaul of the current risk-assessment policies are included. These changes would affect both scientific analyses of risks and the documents agencies would use for reporting risk assessments. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 13 RISK ASSESSMENT ------- ASSESSMENT GUIDELINES Appropriate role of risk assessment in risk analysis DeRosa, C. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Environmental Monitoring and Assessment Program Assessment Framework Thornton KW, Saul GE, Hyatt DE FTN Associates, Little Rock, AR. Govt Reports Announcements & index (GRA&I), Issue 14, 1994 NTIS/PB94-158862, 53p NTIS Prices: PC A04/MF A01 Contract EPA-68-DO-0093 Environmental Protection Agency, Research Triangle Park, NC. Environmental Monitoring and Assessment Program. The document presents a framework for conducting assessments in the Environmental Monitoring and Assessment Program (AP). The framework describes basic elements of the assessment process and provides a common foundation for conducting assessments within AP. Because of its general nature, the framework should be adaptable to a diverse set of assessment questions and needs. Consequently, the document is written to assist science administrators and resource managers in understanding the AP assessment process. See also PB94-114915. Sponsored by Environmental Protection Agency, Research Triangle Park, NC. Environmental Monitoring and Assessment Program. TOXLINE Environmental Risk Assessment of New Chemicals Under the Toxic Substances Control Act (TSCA) Section Five Nabholz, J. V. EPA, Washington, DC; Miller, P.; Zeeman, M. ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p40(16) Language: English Full text available from Congressional Information Service. RISK ASSESSMENT 14 ------- Section 5 of TSCA requires premanufacture reporting requirements .for new chemicals. These Premanufacture Notifications (PMNs) must include chemical identity, molecular structure, trade name, production volume, uses and amount for each use, by-products, and impurities. If risk is identified for a specific chemical after review of the PMN, it is subjected to either a more in-depth assessment or it is regulated directly. The risk-assessment procedure involves: determining a hazard profile using six effective concentrations; determining a concern concentration (CC); exposure assessment, in which a predicted environmental concentration (PEC) is determined; and risk assessment, which compares the CC to the PEC. As illustration of the testing protocol, case studies are described for neutral organic chemicals, organic chemicals showing excess toxicity, surfactants, polyanionic monomers, compounds that hydrolyze/react and polymerize, and compounds that hydrolyze/react and do not polymerize. DIALOG(R)File 40:Enviroline{R) (c) 1994 CIS, Inc. All its. reserv. EPA Airs Shift Toward Pollution Prevention Ember, Lois Chem Eng News Aug 9 93 v71, n32, p17(1) Language: English journal article The EPA's Office of Pollution Prevention and Toxics (OPPT) has recently announced a shift in policy toward an emphasis on pollution prevention and risk reduction. These policy changes will be most apparent in the amendments to the Toxic Substances Control Act. These amendments would require users of chemicals to provide detailed information regarding the processes in which chemicals are utilized. The OPPT is also seeking to develop a list of safer chemicals and processes that can replace existing schemes. The risk management strategies being developed will cover the entire life cycle of chemicals. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 15 RISK ASSESSMENT ------- EPA Continues Probe on Dangers of Showering, Labels Passive Smoking a Carcinogen EPA Watch Sep 30 92 v1, n13, p2(3) Language: English Full text available from Congressional Information Service. newsletter article The results of two studies related to the EPA policies on indoor air quality are discussed. The first study was concerned with the potential health effects of showering. Showering can result in a high exposure to VOCs, depending on factors such as shower duration, droplet size, and water temperature. The second study confirmed environmental tobacco smoke as a human carcinogen. The risk assessment strategies used to evaluate the dangers of second-hand smoke are detailed. Reasons for uncertainties in the exposure data are evaluated, along with the effects of diet on cancer risk. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. EPA Lists Toxic Chemicals to Help Protect Public from Accidental Releases Hanson, David Chem Eng News Jan 31, 94 v72, n5, p16(2) Language: English journal article EPA has released a new list of toxic substances it believes are most likely to be released accidentally and cause injury, including 63 flammable gases and liquids, some high explosives, and 77 acutely toxic chemicals. The list is intended to help communities be aware of public health risks. Chemical makers and other facilities handling the listed chemicals must develop risk management plans to prevent accidental releases. About 115,000 manufacturing plants, treatment and storage facilities, and other sites are affected. There is some overlap between the EPA list and a similar OSHA list, but the latter does not include hazardous flammable chemicals as defined by EPA. The Chemical Manufacturers Association believes EPA-OSHA duplication is confusing, and that EPA criteria for choosing chemicals to list are not justified. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 16 ------- EPA Plans More Flexible Guidelines to Assess Cancer Risk from Chemicals Hanson, David Chem Eng News Dec 21 92 v70, n51, pi3(2) Language: English journal article EPA intends to revise the way it estimates the cancer risk posed by chemicals, and new cancer assessment guidelines are expected to be more flexible than existing ones. New draft documents reveal an increased emphasis on providing characterization analyses for each component of the risk assessment. A narrative weight of evidence characterization statement may displace the traditional alphanumeric ranking of chemical cancer risk. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. EPA Proposes Chemical Risk Management Rule to Prevent, Prepare for Accidental Releases Occup Saf Health Report-BNA Oct 27 93 v23, n22, p647(30) Language: English Full text available from Congressional Information Service. journal article 4 table(s) Under the 1990 amendments to the Clean Air Act, EPA plans to introduce regulations that*would mandate risk management programs at sites where significant quantities of certain hazardous substances are used or produced. Risk management programs would be available for public review at local planning agencies, state governments, the Chemical Safety & Hazard Investigation Board, and EPA itself. The proposed regulations have evolved in response to growing public awareness of the risks to health and the environment posed by many industrial chemicals. All facets of the proposed regulations are thoroughly discussed. Comments concerning the regulations will be accepted until February 16, 1994. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 17 RISK ASSESSMENT ------- EPA's approach to environmental research in the 90s Bretthauer, E.W. Off, Res., Univ. Nevada, 4505 Maryland Pkwy., Las Vegas, NV 89154-1046, USA 13. Annual Meeting, Society of Environmental Toxicology and Chemistry, Cincinnati, OH (USAJ620 pp. 1331-1333 ENVIRON. TOXICOL. CHEM VOL. 12, NO. 8 1993 Language: ENGLISH In the past four years the U.S. Environmental Protection Agency (EPA) has changed its approach to dealing with environmental problems, which resulted in placing much more emphasis on science. Whenever possible the Agency concentrates on addressing the highest environmental risks, stresses pollution prevention, prefers voluntary programs to regulatory approaches, and makes more use of the marketplace to achieve environmental goals. To meet the need for more technical information to support this approach, the EPA changed its planning process, increased its ecological research program, developed the Environmental Monitoring and Assessment Program (EMAP), increased its emphasis on reproductive and developmental toxicology and neurotoxicology, and restructured its approaches to risk assessment. The Agency also significantly increased its relationships with academia and the private sector in implementing its research program. DIALOG(R)File 41 :Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Guidance for data useability in risk assessment Bleyler, R.; Isaacson, P.; Kaleri, C. U.S. EPA Reg. VI Federal Environmental Restoration '92, Vienna, VA (USA), 15-17 Apr 1992 Hazardous Materials Control Research Institute HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA. Fax: (301) 220-3870. Telephone: (301) 982-9500., Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 18 ------- How "safe" is the ground water Americans drink? Dourson, M.L.; Jordan, W.L. GROUND WATER MONIT. REV VOL. 9, NO. 4 pp. 73-74 1989 Special issue: Agricultural chemicals. Language: ENGLISH Despite a tremendous amount of information regarding the presence of contaminants, and particularly pesticides, in ground water (Garner et al. 1986), no clear-cut answers exist to questions about how "safe" are ground water resources in the USA. This is due, in part, to the inability of current assessment methods to characterize the health risk at various exposures, making it difficult, therefore, to determine a strict demarcation between what is safe and "not safe." However, significant data gaps in the toxicity and exposure to these pesticides exist as well. In some cases the answers to such questions may only be as related to other safe exposures. Recent activities by the U.S. Environmental Protection Agency (EPA) are helping risk managers and private citizens better understand these questions and the tentative answers that currently available data suggest. This paper briefly reviews two efforts by the EPA to characterize the extent of pesticide contamination of ground water - the Pesticides in Ground Water Data Base: Interim Report and the subsequent National Pesticide Survey. The paper will briefly mention the methods by which the EPA develops estimates of health risk and then review what is known about the risks posed by pesticide residues in ground water from this interim report. DIALOG(R)File 4*l:Poilution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Interpretation of male rat renal tubule tumors Presented at: International Symposium on the Health Effects of Gasoline, Miami, FL (USA), 5-8 Nov 1991 Rodgers, I.S.; Baetcke, K.P. CWP Assoc., 2302 Eagle Rock PL, Silver Spring, MD 20906, USA ENVIRON. HEALTH PERSPECT. SUPPL.; 101(6), pp. 45-52, 1993 Language: English Based on an analysis of recent scientific studies, a Technical Panel of the U.S. Environmental Protection Agency's (EPA) Risk Assessment Forum recently advised EPA risk assessors against using information on certain male rat renal tubule tumors to assess human risk under conditions specified in a new Forum report. Risk assessment approaches generally assume that chemicals producing tumors in laboratory animals are a potential cancer hazard to humans. For most chemicals, including 19 RISK ASSESSMENT ------- classical rodent kidney carcinogens such as N-ethyl-N-hydroxyethylnitro samine, this extrapolation remains appropriate. Some chemicals, however, induce accumulation of alpha sub(2u)-globulin ( alpha sub(2u)-g), a low molecular weight protein, in the male rat kidney. The alpha sub(2u)-g accumulation initiates a sequence of events that appears to lead to renal tubule tumor formation. Female rats and other laboratory mammals administered the same chemicals do not accumulate low molecular weight protein in the kidney, and they do not develop renal tubule tumors. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. Mutagenicity test schemes and guidelines: U.S. EPA Office of Pollution Prevention and Toxics and Office of Pesticide Programs Auletta, A.E.; Dearfield, K.L.; Cimino, M.C. U.S. EPA, Off. Pollut. Prev. and Toxics, (TS-796), 401 M St. SW, Washington, DC 20024, USA ENVIRON. MOL. MUTAG VOL. 21, NO. 1 pp. 38-45 1993 Language: ENGLISH New requirements for chemicals subject to mutagenicity testing from the U.S. Environmental Protection Agency (USEPA) are discussed. Also detailed are two categories in the 1986 Mutagenicity Risk Assessment Guidelines. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Prioritizing ecological and human welfare risks from environmental stresses Harwell, M.A.; Cooper, W.; Flaak, R. Rosenstiel Sch. Mar. and Atmos. Sci., Univ. Miami, Miami, FL 33149, USA ENVIRON. MANAGE VOL. 16, NO. 4 pp. 451-464 1992 Language: ENGLISH The ecological systems of Earth are subjected to a wide array of environmental stresses resulting from human activities. The development of appropriate environmental protection and management policies and the appropriate allocation of resources across environmental stresses require a systematic evaluation of relative risks. The data and methodologies for comprehensive ecological risk assessment do not exist, yet we do have considerable understanding of ecological stress-response relationships. A methodology is presented to utilize RISK ASSESSMENT 20 ------- present knowledge for assignment of relative risks to ecological systems and human welfare from anthropogenic stresses. The resultant priorities, developed for the US Environmental Protection Agency's (EPA) relative risk reduction project, highlight global climate change, habitat alteration, stratospheric ozone depletion, and species depletion as the highest environmental risks, significantly diverging from the present emphasis by EPA and the public on toxic chemical issues. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. A quality process for chemical product risk assessment Weiler ED, Jayjock MA, Scribner HE Product Integrity Department, Rohm and Haas Company, Philadelphia, PA 19105. Qual Assur 1992 Oct; 1(4)-.295-301 Language: English JOURNAL ARTICLE One cannot manage a health or environmental risk of unknown dimension. Thus, the rational and cost-effective control of any risk lies first in its reasoned assessment. The assessment of risk is a scientific endeavor which embodies the intellectual use of information to reach a determination or assignment of an ascribed level of danger. As such, it is potentially subject to a myriad of subjective interpretations from individuals with special interests and perspectives. This paper attempts to outline a rational and prudent consensus-based system for the quality assurance of risk assessment concerned with the danger to human health and the environment posed by the use of chemical products. We present it as a model that we hope could be accepted and implemented. MEDLINE Reassessing the scope of federal biotechnology oversight Mostow, Peter Pace Environmental Law Review 10 n1 227-273 Fall, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Revising the Risk Assessment Paradigm: Limits on the Quantitative Ranking of Environmental Problems Silbergeld, Ellen K. Comparative Environ Risk Assessment (Lewis) 1993 p73(6) Language: English Full text available from Congressional Information Service. 21 RISK ASSESSMENT ------- EPA has adopted a policy of prioritizing activities according to relative risks. Underlying this policy is the assumption that risk assessment is a valid and accurate tool for prioritizing critical issues. The policy is challenged on two grounds. First, EPA has failed to act at all on critical issues rather than act inappropriately. Second, the resources available to the agency to deal with environmental problems are vast and do not justify prioritization and, thus, limitations to environmental protection. Both practical and conceptual limits to quantitative risk assessment challenge its applicability. A public health perspective would focus on disease prevention through environmental prevention. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Risk assessment based on current release standards for radioactive surface contamination Chen SY Argonne National Lab., IL. Govt Reports Announcements & Index (GRA&I), Issue 07, 1994 NTIS/DE94001435, lOp NTIS Prices: PC A02/MF A01 ANL/EAIS/CP-79677, Contract W-31109-ENG-38 Department of Energy, Washington, DC. Standards for uncontrolled releases of radioactive surface contamination have been in existence in the United States for about two decades. This paper reviews the technical basis of published standards, identifies areas in need of revision, provides risk interpretations based on current technical knowledge and the regulatory environment, and offers suggestions for improvements. TOXLINE Simplified approach to environmental risk assessment at superfund sites Block, R.M. Aqua Terra Technologies R&D '92: National R&D Conference on the Control of Hazardous Materials, San Francisco, CA (USA), 4-6 Feb 1992 Hazardous Materials Control Research Institute; Association of Bay Area Governments R&D '92, 7237 Hanover Parkway, Greenbelt, MD 20770-3602 USA. Telephone: (301) 982-9500. Fax: (301) 220-3870., Proceedings, $45.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 22 ------- Strategies for contracting for quality risk assessment data Baldwin, J. Baldwin Consult. Serv. HazMat/lnternational '93: 11th Annual Presentation, Atlantic City, NJ (USA), 9-11 Jun 1993 HAZMAT WORLD; Department of Commerce, International Trade Administration; State of New Jersey Advanstar Exposition, 800 Roosevelt Rd., Build. E, Suite 408, Glen Ellyn, IL 60137-5835, USA; Telephone: (708) 469-3373; Fax: (708) 469-7477, Proceedings, $105.00 plus $10.00 shipping charge Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Validation of some extrapolation methods used for effect assessment Emans, H.J.B.; Plassche, E.J.V.D.; Canton, J.H.*; Okkerman, P.C.; Sparenburg, P.M. Natl. Inst. Public Health and Environ. Prot., P.O. Box 1, 3720 BA Bilthoven, Netherlands ENVIRON. TOXICOL. CHEM.; 12(11), pp. 2139-2154, 1993 Language: English For effect assessment several extrapolation methods can be used to derive the concentration of toxic chemicals above which adverse effects on aquatic ecosystems may occur. These methods are based on single-species toxicity data. At present, however, it is uncertain whether the values calculated with these extrapolation methods really represent accurate estimations of concentrations harmless to ecosystems. Therefore a validation of extrapolation methods was carried out by comparing NOECs derived from multiple-species (semi-) field experiments with extrapolated values. In this study validation was restricted to the methods of Aldenberg and Slob and Wagner and Lokke and a modification of the method of the U.S. Environmental Protection Agency. It is concluded that single-species toxicity data can be used to derive "safe" values for the aquatic ecosystem. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. 23 RISK ASSESSMENT ------- LEGAL ASPECTS Analyses of natural resources in 10 CFR part 60 as related to inadvertent human intrusion Miklas, Michael P.; Lefevre, Harold E. Cent for Nuclear Waste Regulatory Analyses, San Antonio, TX, USA Proceedings of the 4th Annual International Conference on High Level Radioactive Waste Management Language: English The purpose of this paper is to examine the intent of the regulatory language of the portions of 10 CFR Part 60 which deal with considerations of the natural resources of a proposed geologic repository for high-level radioactive wastes as they relate to inadvertent human intrusion. Four Potentially Adverse Conditions (PAC) and the requirements of 10 CFR 60.21(c)(13) are shown to be related to natural resources. The Commission intends for DOE to evaluate the likelihood and consequence of inadvertent human intrusion into a geologic repository as a result of exploration or exploitation of natural resources within or near a proposed high-level radioactive waste geologic repository. (Author abstract) 14 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Environmental health risk assessment: Regulatory approach to assessing public health risks of a toxic chemical spill in the Sacramento River DiBartolomeis, M^J. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Magnitude of compounding conservatisms in Superfund risk assessments Burmaster, D.E.; Harris, R.H. Alceon Corp., P.O. Box 2669, Harvard Square Stn., Cambridge, MA 02238-2669, USA RISK ANAL VOL. 13, NO. 2 pp. 131-134 1993 Language: ENGLISH The U.S. Environmental Protection Agency (EPA) has made two crucial risk management decisions in defining how much clean-up is enough at RISK ASSESSMENT 24 ------- Superfund sites: first, the postremediation cancer risk goal should •. fall within the range of 10 super(-4) to 10 super(-6); and, second, the postremediation cancer risk goal should not be exceeded by more than 5-10% of the populations potentially exposed. Unfortunately, the EPA has also issued guidance documents that distort these fundamental risk management criteria by specifying risk assessment methodologies and exposure factors that do not achieve the RME as defined by the EPA because they compound conservative assumptions beyond the RME concept. These EPA documents specify a methodology that results in exposure and risk estimates well in excess of the 99th percentile, thus leading to clean-up decisions that are based on acceptable health risks that virtually no one in the surrounding population would be expected to experience. In effect, the EPA has established risk management criteria based on acceptable risks, and has then issued risk assessment guidelines that lead to clean-up requirements that will achieve a far greater degree of health protection. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. NFS and NEPA: An analysis of the legal impact of the UN principles relevant to the use of nuclear power sources in outer space on the current practice of environmental risk assessment under domestics Neher, P.J. Office Judge Advocat General, Administrative Law Div., Alexandria, VA, USA 44th International Astronautical Congress, Graz, Austria, 16-22 October 1993 International Astronautical Federation; International Institue of Space Law; International Academy of Astronautics; Joanneum Research J. Hess Aerospace Consultant, 12782 Spring Street Garden Grove, VA 96245, Proceedings Paper No. IISL.4.-93-836 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Risk and the New Rules of Decisionmaking: the Need for a Single Risk Target Sarno, Douglas J. Phoenix Environ Corp, Alexandria, VA Environ Law Report Jul 94 v24, n7, p10402(4) Language: English Full text available from Congressional Information Service. journal article 21 reference(s) 25 RISK ASSESSMENT ------- Three issues have emerged to push the government toward goals of. increased rationality, consistency, and accountability in the Superfund program. Concerns about environmental justice have moved to the forefront, and restrictions on future land use have become widely accepted tools for improving the rationality of decision making. The decision making role of the public has been enlarged, as DOE and EPA have given full support to increasing citizen participation in decision making. In light of these changes, the government must establish a single, nationwide risk target to apply at each site to foster effective public participation in cleanup decisions and to achieve a consistent level of protection, regardless of the socioeconomic status of affected communities. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Senators show support for measure requiring environmental risk assessment Anon. HAZMAT NEWS VOL. 3, NO. 19' pp. 7-8 1992 Language: ENGLISH A bill that would designate the EPA to rank risks and benefits of environmental threats received overall support by most witnesses and senators at a Senate committee hearing held Sept 18. However, questions about how risk-ranking would affect current laws were raised by two key senators with long-standing environmental credentials. The senators warned that a ranking system might impinge on their proper role as congressional policy-makers in the environmental arena. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RISK ASSESSMENT 26 ------- METHODS OF ESTIMATING RISK Development of SAR/QSAR for use under EPA's Toxic Substances Control Act (TSCA): An introduction Zeeman, Maurice; Nabholz, J. Vincent; Clements, Richard G. U.S. Environmental Protection Agency, Washington, DC, USA Proceedings of the Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial, Pittsburgh, PA, USA Language: English EPA assesses the environmental fate, hazards, and risks of all new industrial chemicals in the U.S. prior to their commercial manufacture in or import into this country. Within 90 days decisions must be made whether to allow each chemicals manufacture or import. There is no requirement to do testing and only about 5% of the PMN's contain any chemical fate or ecotoxicological test data. This has resulted in the development and use of general and quantitative chemical structure activity relationships (SAR/QSAR's) for estimating a chemical's physical/chemical properties, ability to degrade and bioconcentrate, and its toxicity to fish, aquatic invertebrates, and algae. QSARs are also being used to screen for these characteristics in the over 70,000 existing chemicals in the TSCA Inventory. (Author abstract) Refs. DIALOG(R)Rle 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. DRASTIC Mapping to Determine the Vulnerability of Ground Water to Pollution Trent, Victoria P. Georgia Geologic Survey, Atlanta AWRA/et al Geographic Information Systems & Water Resources Symp, Mobile, AL Mar 14-17 93 p537(8) Language: English Full text available from Congressional Information Service. conf paper The vulnerability of the shallow aquifer in Georgia to pollution from surface sources has been documented in a 1:5,000,000 scale map. The EPA's DRASTIC model was used to systematically determine the relative vulnerability of each hydrogeologic circumstance. Mapping can be accomplished using existing data, and will provide a standardized foundation for environmental decision making. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 27 RISK ASSESSMENT ------- Environmental Decision Models: U.S. Experience and a New Approach to Pollution Management Haynes, Kingsley E. George Mason Univ, Fairfax, VA; Ratick, Samuel; Bowen, William M.; Cummings-Saxton, James Environ Int 1993 v19, n3, p261(!5) Language: English journal article 3 diagram(s); 69 reference(s) An overview is presented of the decision models used to support US environmental policymaking. They include cost/benefit analysis and risk assessment. Cost/benefit analysis specifies some environmental objective or goal and then identifies the costs associated with various methods of meeting that goal. Risk analysis is similar to cost/benefit analysis, but it is usually placed in a framework that involves public health issues. The problem with risk analysis is that risk is not an objective phenomenon perceived in the same way by all interested parties. Analytical methods represented by cost/benefit and risk assessment generate different priorities. Recent pollution-control efforts are focusing on pollution-prevention measures, so measurement techniques must be developed that can allow EPA to accurately assess pollution-prevention potential and to measure the progress of industry toward specific prevention goals. D!ALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Environmental risk assessment questionnaire Lowell, David T. Practical Real Estate Lawyer 8 n6 43-50 Nov, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. From rats to regulations; environmental risk assessment based on the health effects of substances on rodents is widespread, costly, and unreliable Schwartz, Richard E.; Davis, Robert C., Jr. Legal Times 15 n29 S6(4) Dec 7, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. RISK ASSESSMENT 28 ------- The Hawaii Environmental Risk Ranking Study Carpenter, Richard A. East-West Center, Honolulu, HI NatJ Assoc of Environ Professionals 18th Annual Conf Proc, Seattle, WA May 6-8 92 p291(12) Language: English Full text available from Congressional Information Service. 4 table(s) The Hawaii Environmental Risk Ranking Study, funded partially by federal grants and executed by volunteers affiliated with the Hawaii Assoc of Environ Professionals (HAEP), comparatively ranks hazards to humans and natural ecosystems. On the basis of EPA guidelines for risk assessment, the results of the study will guide the government in setting priorities for attending to hazards and reducing risks. The top three environmental problem areas were identified as industrial wastewater discharges, municipal wastewater treatment and discharges, and drinking water quality. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Inadequacy of commonly used risk assessment guidance for determining whether solvent-contaminated soils can affect groundwater at arid sites Korte, N.E.; Gleason, T.A.; Beale, J.S.; Kearl, P.M. Oak Ridge National Laboratory, Grand Junction, CO, USA Journal of Environmental Science and Health, Part A: Environmental Science and Engineering v 27 n 8 Dec 1992. p 2251-2261 Language: English Commonly used risk assessment guidance is not adequate when applied to solvent-contaminated soils in arid environments. The equations that are recommended for calculating how such soils will affect groundwater assume that liquid phase leaching controls contaminant migration. If vapor phase migration is considered at all, diffusion is assumed to be the dominant process. In contrast, a field study performed at an industrial site in Southern California demonstrated that leaching could not account for the transport of contaminants to the water table and the recent technical literature suggests that gravity-induced vapor migration may be the principal mechanism for vapor phase migration. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. 29 RISK ASSESSMENT ------- Indoor air: Potential health risks related to residential wood smoke, -. as determined under the assumptions of the US EPA risk assessment model Sidhu, K.S.; Hesse, J.L.; Bloomer, A.W. Health Risk Assess. Div., Michigan Dep. Public Health, 3423 N. Logan St./Martin Luther King Jr. Blvd., Box 30195, Lansing, Ml 48909, USA INDOOR ENVIRON.; 2(2), pp. 92-97, 1993 Language: English Residential wood smoke contains inorganic and organic particulates, ash, carbon monoxide, nitric oxide, nitrogen dioxide, formaldehyde, polycyclic aromatic hydrocarbons (benzo[a]pyrene, benzo[k]fluoranthene, benzo[b]fluoranthene, benzo[ghi]perylene, and indeno[1,2,3-cd]pyrene), phenols and sulfur dioxide. Benzo[a]pyrene and formaldehyde are classified as group B sub(2) and group B sub(1) carcinogens, respectively, by the United States Environmental Protection Agency. Reported concentrations and potential health risks of the released contaminants are discussed. In general, wood smoke is an irritant to the eyes, nose, and the respiratory tract. It has the potential to cause chronic respiratory problems. Because there are indications that wood smoke may cause adverse effects on human health, exposure to this source of air pollution should be minimized. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. An inter- and intra-agency survey of the use of plants for toxicity assessment * Smith, B.M.; Gorsuch, J.W.; Lower, W.R.; Lewis, M.A.; Wang, Wucheng (eds.) San Francisco Bay Regional Water Qual. Control Board, Oakland, CA94612, USA 2. Symp. on Use of Plants for Toxicity Assessment, San Francisco, CA (USA)620 pp. 41-59 PLANTS FOR TOXICITY ASSESSMENT: SECOND VOLUME AMERICAN SOCIETY FOR TESTING AND MATERIALS, PHILADELPHIA, PA (USA) Language: ENGLISH The purpose of this project was to perform an inter- and intraagency survey of the use of plants as test systems for ecological risk assessment and remediation for the United States Environmental Protection Agency Office of Research Development (USEPA/ORD). Four broad classes of plant applications were identified: (1) bioassays; (21 bioindicators; (3) bioremediation; and (4) biotechnology. Improvement to research methodologies would include: (1) developing fluorescence RISK ASSESSMENT 30 ------- bioassays for terrestrial and aquatic plants and algae and combining. plant and animal tests to form regionally differentiated suites of bioassays; (2) development of "natural community" databases and small-scale maps for evaluation of changes in plant community structure to determine the "biotic integrity" of specific habitat types; (3) expand work to develop plants and fungi as biologic remediative tools; and (4) development of guidelines for field trials and eventual full-scale agricultural use of pesticide-producing genetically engineered plants (GEPs). DIALOG{R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. AH rts. reserv. Intel-laboratory comparison of the early life-stage toxicity test using sheepshead minnows (Cyprinodon variegatus) Presented at: 14. ASTM Symp. on Aquatic Toxicology and Risk Assessment, San Francisco, CA (USA), 22-24 Apr 1990 Hansen, D.J.; Cripe, G.M. U.S. EPA, Environ. Res. Lab., Narragansett, Rl 02882, USA AQUAT. TOXICOL. RISK ASSESS., Publ. by: AMERICAN SOCIETY FOR TESTING AND MATERIALS, PHILADELPHIA, PA (USA), 1991, pp. 354-375 In AQUATIC TOXICOLOGY AND RISK ASSESSMENT: FOURTEENTH VOLUME. Mayes, M.A. Barron, M.G. (eds.), 1991 ISBN 0-8031-1.425-7 Language: English The interlaboratory precision of the ASTM early life-stage toxicity test with the sheepshead minnow (Cyprinodon variegatus) was investigated at five contract and two EPA laboratories using endosulfan and pentachlorobenzene. Each laboratory conducted two tests with each chemical. Tests began with newly fertilized to 48-hour-old embryos, continued through embryonic development, hatching, and growth of fish to the juvenile stage, and were terminated after 28 days. Effects on survival of embryos, survival of hatched fish, and weight of surviving fish were quantified. Criteria were developed for judging acceptability of test results and for selecting the upper and lower chronic values. Using these criteria, 19 of the 28 tests (68%) were judged acceptable. Results from the early life-stage toxicity test were reasonably reproducible within and between laboratories. Ratios of the high-to-low chronic value from acceptable duplicate tests for each chemical tested within laboratories ranged from 1.04 to 1.99 for eight of nine tests. For nine acceptable paired tests, the average ratio was 1.98; the coefficient of variation was 80%. Variability of chronic values across 31 RISK ASSESSMENT ------- all laboratories was generally reproducible within a factor of two. • Chronic values from all acceptable tests averaged 0.60 mu g/L (coefficient of variation 73%) for endosulfan and 82 mu g/L (coefficient of variation 54%) for pentachlorobenzene. Neither survival nor weight were consistently the endpoint most sensitive in tests with either chemical. The interlaboratory variability of the results of this test was particularly good relative to variability of other tests considering the following: the test was complex; the laboratories were inexperienced; the embryos were from Atlantic and Gulf Coasts; and test water was from the Atlantic, Gulf, and Pacific Coasts. Variation in this and other toxicity and bioconcentration tests using marine species should be considered when judging the environmental implications of results. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All its. reserv. International toxicity equivalency factor (I-TEF) method for estimating risks associated with exposures to complex mixtures of dioxins and related compounds Kutz, F.W.; Barnes, D.G.; Bretthauer, E.W.; Bottimore, D.P.; Greim, H. U.S. Environ. Prot. Agency, Washington, DC 20460, USA TOXICOL. ENVIRON. CHEM.; 26(1-4), pp. 99-109, 1990 Language: English Journal article-original research Subfile: 24 Toxicology Abstracts The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is a revised interim procedure for assessing the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). This updated scheme was developed by a working group of the North Atlantic Treaty Organization's committee on the Challenges of Modern Society and has been officially adopted by the U.S. Environmental Protection Agency (EPA), Canada, Ontario Ministry of the Environment, the Nordic countries, the Netherlands, and the United Kingdom. The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 32 ------- Introduction: Methods for environmental quantitative risk assessment Anon. 7. Symposium on Environmental Epidemiology: Methods for Environmental Quantitative Risk Assessment, Pittsburgh, PA (USA) ENVIRON. HEALTH PERSPECT VOL. 90 p. 157 1991 Language: ENGLISH This symposium is the seventh in a series presented by the Environmental Protection Agency and the Center for Environmental Epidemiology of the University of Pittsburgh. The symposium was organized by Carol K. Redmond and Joseph P. Costantino of the Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh. The objective of the organizers was to develop a program that would present recent advances in methodologies for assessing health risk for environmental exposures; provide health researchers with information useful to evaluate the impact of environmental exposures; and assess the evidence for human health effects from exposures to selected environmental pollutants. DIALOG{R)File 41 :Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. A Method for Assessing Environmental Risk: a Case Study of Green Bay, Lake Michigan, USA Harris, Hallett J. University of Wisconsin, Green Bay; Wenger, Robert B.; Harris, Victoria B.; Devault, David S. Environ Manag-Springer-Verlag Mar-Apr 94 v18, n2, p295(12) Language: English Full text available from Congressional Information Service. research article An ecological risk assessment methodology was developed to support the EPA Science Advisory Board recommendation that risk reduction strategies focus on ecological risk as much as on public health, and that protection efforts aim at opportunities for the greatest risk reduction. The methodology is based on a fuzzy-set decision model. The methodology was tested in a case study of the Green Bay ecosystem in Lake Michigan. Risk values were assigned by experts through a group consensus process. The risks were ranked analytically from several perspectives, such as remediation management and prevention management. The fuzzy set methodology is useful for distinguishing environmental risks and the relative importance of interrelated problems. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 33 RISK ASSESSMENT ------- Multimedia transport, fate, exposure and risk assessment: Strategies developing evaluative, integrative computer software Van de Water, R.; Cohen, Y. Univ. California, Los Angeles 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-WA-76.02 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Odor thresholds in relation to risk assessment Cha, S.S.; Ginsberg, G.L. TRC Environmental Corp. 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-MP-19.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Performance evaluation of sperm cell toxicity test using the sea urchin, Arbacia punctulata Presented at: 14. ASTM Symp. on Aquatic Toxicology and Risk Assessment, San Francisco, CA (USA), 22-24 Apr 1990 Nacci, D.; Comeleo, P.; Petrocelli, E.; Kuhn-Hines, A.; Modica, G.; Morrison, G. Science Applications Internatl. Corp., Mar. Serv. Branch; c/o U.S. EPA ERL-N, Narragansett, Rl 02882, USA AQUAT. TOXICOL. RISK ASSESS., Publ. by: AMERICAN SOCIETY FOR TESTING AND MATERIALS, PHILADELPHIA, PA (USA), 1991, pp. 324-336 In AQUATIC TOXICOLOGY AND RISK ASSESSMENT: FOURTEENTH VOLUME. Mayes, M.A. Barren, M.G. (eds.), 1991 ISBN 0-8031-1425-7 Language: English The sperm cell toxicity test using the sea urchin, Arbacia punctulata, is a short-term chronic procedure using fertilization as an indicator of toxicity to marine and estuarine organisms. Toxicity tests of effluents, receiving waters, and single compounds performed as part of RISK ASSESSMENT 34 ------- the U.S. Environmental Protection Agency's Marine/Estuarine Complex Effluent Toxicity Testing Program, were reviewed to evaluate this method for reliability, precision, seasonal consistency, and sensitivity. Routine testing was performed using fertile adult urchins maintained in natural seawater aquaria. A 97.7% success rate (control fertilization exceeded 50%) was achieved for 346 tests conducted between June 1986 and November 1989. During this time, four sets of tests using two reference toxicants, copper (as copper sulfate) and sodium dodecyl sulfate (SDS), were conducted to establish intralaboratory test precision. For these sets of 3 to 5 tests each, test precision, calculated as coefficients of variation (CV), ranged from 22.0 to 54.0%. There were no obvious seasonal trends in test success rate, sensitivity, or variability. Sperm test results of these two reference toxicants and 33 complex effluent studies were ranked for sensitivity when compared to results of concurrent short-term chronic marine toxicity tests using marine/estuarine species of algae, mysids, and fish. Of the five test types compared, the sperm test was intermediate in sensitivity. A second set of fertile urchins were maintained and tested using a noncommercial artificial seawater formulation. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. PHA case study using HAZOP and selective application of quantitative risk assessment Puglionesi, P.S.; Nowak, G.D.; Tittensor, J.G. Roy F. Weston, West Chester, PA, USA 1993 AlChE Summer National Meeting, Seattle, WA (USA), 15-18 Aug 1993 American Institute of Chemical Engineers (AlChE) AIChE345 East 47th Street, New York, NY 10017, USA; Telephone: (212) 705-7344; Fax: (212) 752-3294, Proceedings Paper No. 65c Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Predicting risk by looking at the past; health dangers for exposed workers and the public can be assessed by reconstructing a facility's processes and products. (World in Peril: Responding to Expanding Environmental Enforcement) Ripple, Stephen Legal Times 15 n29 S12(4) Dec 7, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. 35 RISK ASSESSMENT ------- Prediction of Vulnerable Zones for Reactive Substances Miller, Michael K.; Wong, Kau-Fui Vincent Greiner Inc, Miami, FL J Environ Health Oct 93 v56, n3, p17(3) Language: English Full text available from Congressional Information Service. journal article 1 map(s); 6 reference(s); 1 tablets) Atmospheric pollutant-dispersion models are increasingly being used by community emergency-planning committees to determine vulnerable zones in their communities resulting from accidental releases of hazardous substances. Some form of the Gaussian dispersion model is usually used to analyze the release of these hazardous substances, which are delineated by EPA in its +i Technical Guidance for Hazards Analysis-fr . A typical Gaussian model is described, in which the vulnerable zone is determined by plume spread in both the horizontal and vertical directions. Vulnerable zones are determined for fluorine and for boron trisulfide. Modeling results suggest that these compounds can be more dangerous that EPA recommendations, since the +i Technical Guidance for Hazards Analysis +r does not consider substance reactivity. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Presentation of a general algorithm to include effect assessment on secondary poisoning in the derivation of environmental quality criteria. Part 1. Aquatic food chains Romijn CA, Luttik R, van de Meent D, Slooff W, Canton JH National Institute of Public Health and Environmental Protection (RIVM), Bilthoven, The Netherlands. Ecotoxicol Environ Safety 1993 Aug;26(1):61-85 Language: English JOURNAL ARTICLE Effect assessment on secondary poisoning can be an asset to effect assessments on direct poisoning in setting quality criteria for the environment. This study presents an algorithm for effect assessment on secondary poisoning. The water-fish-fish-eating bird or mammal pathway was analyzed as an example of a secondary poisoning pathway. Parameters used in this algorithm are the bioconcentration factor for fish (BCF) and the no-observed-effect concentration for the group of fish-eating birds and mammals (NOECfish-eater). For the derivation of reliable BCFs preference is given to the use of experimentally derived BCFs over QSAR estimates. NOECs for fish eaters are derived by extrapolating toxicity data RISK ASSESSMENT 36 ------- on single species. Because data on fish-eating species are seldom available, toxicity data on all birds and mammalian species were used. The proposed algorithm (MAR = NOECfish-eater/BCF) was used to calculate MARS (maximum acceptable risk levels) for the compounds lindane, dieldrin, cadmium, mercury, PCB153, and PCB118. By subsequently comparing these MARs to MARs derived by effect assessment for aquatic organisms, it was concluded that for methyl mercury and PCB153 secondary poisoning of fish-eating birds and mammals could be a critical pathway. For these compounds, effects on populations of fish-eating birds and mammals can occur at levels in surface water below the MAR calculated for aquatic ecosystems. Secondary poisoning of fish-eating birds and mammals is not likely to occur for cadmium at levels in water below the MAR calculated for aquatic ecosystems. MEDLINE Review of Ecological Effects and Bioconcentration Testing Recommended by the TSCA Interagency Testing Committee and Implemented by EPA Under the Toxic Substances Control Act: Chemicals, Tests, and Methods Walker, John D. EPA, Washington, DC ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p92(24) Language: English Full text available from Congressional Information Service. conf paper 71 reference(s); 7 table(s) Section 4 of TST^A requires that EPA publish notices in the Federal Register which request ecological effects and bioconcentration testing for chemical analysis. The types and numbers of tests that have been requested and received are also listed. The TSCA Interagency Testing Committee was created to identify chemicals and chemical groups that should receive priority testing consideration and to recommend them for testing. EPA receives approximately six ecological effects tests per chemical. The methods used to develop bioconcentration and ecological effects test data are described, including bioconcentration test methods, algal bioassay methods, bacterial bioassay methods, acute toxicity test methods, subchronic toxicity tests, partial life-cycle tests, life-cycle tests, reproductive effects tests, and seed germination tests. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 37 RISK ASSESSMENT ------- Risk assessment methodology: The California experience * Kirkendall, V.; Miesner, E.; Caniparoli, D. CH2M Hill, Portland, OR, USA 1993 AlChE Summer National Meeting, Seattle, WA (USA), 15-18 Aug 1993 American Institute of Chemical Engineers (AlChE) AIChE345 East 47th Street, New York, NY 10017, USA; Telephone; (212) 705-7344; Fax: (212) 752-3294 or (212) 752-3297, Proceedings Paper No. 41e Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Risk assessment methods for establishing clean closure levels Riggenbach, J.D.; Streeter, R.A.; Hess, S.C. ERM-South, 9501 Princess Palm Ave., Tampa, FL, USA International Seminar on Industrial Residuals Management, Salvador, Brazil International Association on Water Pollution Research and Control WATER SCI. TECHNOL VOL. 24, NO. 12 pp. 57-76 1991 Language: ENGLISH Establishment of clean closure concentrations for low levels of hazardous constituents in soils, ground water, and other environmental media by assessing risks to human health and the environment is a tool that is being used with increasing frequency. The four-step process sanctioned by the U.S. Environmental Protection Agency (EPA) includes: 1) hazard identification, 2) exposure assessment, 3) Toxicity assessment, and 4) risk characterization. This paper describes the methodology and applies it to the closure of a hazardous waste surface impoundment in Florida. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Role of property-reactivity relationships in meeting the EPA's needs for environmental fate constants Presented at: Symp. on Structure-Activity and Structure-Property Relationships (SARs) in Environmental Chemistry and Toxicology, PACIFICHEM '89, Honolulu, HI (USA), 17-22 Dec 1989 Donaldson, W.T. Environ. Res. Lab, US EPA, College Station Rd., Athens GA 30613, USA ENVIRON. TOXICOL. CHEM.; 11(7), 1992, pp. 887-891 In STRUCTURE ACTIVITY RELATIONSHIPS FOR ENVIRONMENTAL APPLICATIONS.. Elzerman, A.W. (ed.), 1992 Language: English RISK ASSESSMENT 38 ------- During the next 10 years, the Environmental Protection Agency may consider as many as 70,000 chemicals for potential risk to humans and the environment. As many as 14 kinetic and equilibrium constants can be required for predicting the fate and transport of each chemical, and relatively few reliable constants are available in the literature. Laboratory measurement of the needed constants is prohibitively expensive (as much as $7 billion for all constants and chemicals combined) and too slow for rapid response to site-specific evaluations. Development of reliable computational methods holds promise of a 100- to 1000-fold reduction in cost of providing fate constants within a reasonable time frame. 7DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All its. reserv. Structure/Activity Relationships for Evaluation of Biodegradability in the EPA's Office of Pollution Prevention and Toxics Boethling, Robert S. EPA, Washington, DC ASTM Environ Toxicol & Risk Assess: Aquat, Plant & Terrestrial Symp, Pittsburgh, PA Apr 26-30, 92 p540(15) Language: English Full text available from Congressional Information Service. conf paper 24 reference(s); 4 table(s) Biodegradability estimation is an essential part of the EPA review process for existing and new chemicals for which little data are submitted in premanufacture notices under TSCA. Structure/biodegradability relationships have been developed to facilitate the rapid screening and assessment of such chemicals, but this approach is only applicable to narrowly defined chemical families. Multivariate analysis has been used to establish biodegradability classification models that are more widely applicable. Knowledge-based expert systems, which represent the next generation in the evolution of screening-level structure/biodegradability relationships, are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Temporal Variations in Exposure Data Kim, Nancy K. NY State Dep of Health, Albany Comparative Environ Risk Assessment (Lewis) 1993 pi 55(9) Language: English Full text available from Congressional Information Service. 2 graph(s); 2 map(s); 10 reference(s); 6 table(s) 39 RISK ASSESSMENT ------- Risk assessment has been adopted by EPA as a technique to prioritize environmental problems. Such assessment depends on exposure data, the lack of which makes it difficult to evaluate risks to human health. While toxicological data has been acquired experimentally, exposure data have not been documented. The temporal variations of exposure can significantly affect risks, particularly with respect to air emissions, as is indicated by data from studies of exposure to VOCs. Furthermore, average population exposures do not adequately reflect the risks to individuals exposed at much greater levels. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Transferring federal property using qualitative risk assessment Young, B.M.; Ditto, A. Earth Technology Corp. 1993 Federal Environmental Restoration Conference and Exhibition, Washington, DC (USA), 25-27 May 1993 Hazardous Materials Control Resources Institute (HMCRI); Dep. Energy; Dep. Def.; Army Corps Eng.; Dep. Navy; EPA; Bur. Reclam.; Air Force; Nav. Facil. Eng. Command; Dep. Inter.; Agency Toxic Subst. and Dis. Regist. HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA; Telephone: (301) 982-9500; Fax: (301) 220-3870, Proceedings, HMCRI member: $58.50 and non-member: $65.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. TSCA Interagency Testing Committee's Role in Facilitating Development of Test Methods: Toxicity and Bioconcentration Testing of Chemicals Added to Sediments Walker, John D. EPA, Washington, DC ASTM Environ Toxicol & Risk Assess: Aquat, Plant & Terrestrial Symp, Pittsburgh, PA Apr 26-30, 92 p688(35) Language: English Full text available from Congressional Information Service. conf paper 1 diagram(s); 5 graph(s); 20 reference(s); 9 table(s) Under TSCA chemical testing recommendations, the EPA Interagency Testing Committee has developed or revised test guidelines that cover health effects, chemical fate, and ecological impact. A test protocol was developed to measure the toxicity to tadpoles of branched RISK ASSESSMENT 40 ------- 4-nonylphenol added to sediment. Study guidelines for midge larvae were also devised to assess the toxicity and bioconcentration of anthraquinone, octamethylcyclotetrasiloxane, and tetrabromobisphenol A added to sediment. Opportunities to further modify and improve the reliability of these assays are identified. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Use of microbial risk assessment in setting US drinking water standards Macler, B.A.; Regli, S. U.S. EPA, Reg. 9, San Francisco, CA, USA INT. J. FOOD MICROBIOL.; 18(4), pp. 245-256, 1993 Language: English This paper outlines US EPA's general strategy for using microbial risk assessment to support the development of US National Primary Drinking Water Regulations (NPDWRs). It discusses specifically the use of such risk assessment in the development of upcoming regulations for disinfection of groundwater (Groundwater Disinfection (GWD) Rule) and for control of disinfectants and their chemical byproducts (Disinfectant/Disinfection Byproduct (D/DBP) Rule), and possible amendments to the current Surface Water Treatment Rule (SWTR). The risk assessment and risk management processes explicitly consider acceptable risk values for water-borne microbial pathogens. These values directly influence the regulatory choice of treatment levels and methods. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. The Use of Quantitative Structure-Activity Relationships (QSARs) as Screening Tools in Environmental Assessment Clements, R. G. EPA, Washington, DC; Nabholz, J. Vincent; Johnson, D. E.; Zeeman, M. G. ASTM Environ Toxicol & Risk Assess: Aquat, Plant & Terrestrial Symp, Pittsburgh, PA Apr 26-30, 92 p555(16) Language: English Full text available from Congressional Information Service. conf paper 5 graph(s); 12 reference(s); 5 table(s) The EPA Office of Pollution Prevention & Toxics has effectively used quantitative structure-activity relationships (QSAR) to estimate the inherent toxicity of new chemicals in aquatic systems. The utility of QSARs as screening tools to assess the inherent toxicity of chemicals 41 RISK ASSESSMENT ------- contained in subsets of the TSCA inventory of new and existing chemicals is explored. One QSAR is applied as a general screening tool for the inventory, and specific QSARs are then applied. Frequency distributions for the log of the octanol/water partition coefficient and molecular weights for each inventory are also addressed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Using an uncertainty analysis of direct and indirect exposure to contaminated groundwater to evaluate EPA's MCLs and health-based cleanup goals Finley, B.; Lau, V.; Paustenbach, D. ChemRisk Div., McLaren/Hart Environ. Eng., 1135 Atlantic Ave., Alameda, CA 94501, USA Gulf Coast Hazardous Substance Research Cent. 4. Annu. Symp.: Ground Water — the Problem and Some Solutions, Beaumont, TX (USA) J. HAZARD. MATER VOL. 32, NO. 2-3 pp. 263-274 1992 Special issue: Ground water -- the problem and some solutions. Language: ENGLISH Groundwater which has been contaminated by industrial chemicals has been of significant concern in the U.S. since about 1975. Since then, dozens of regulatory decisions have been made to remediate many of these contaminated aquifers. The selected groundwater clean-up levels will dictate the cost and time frame of the remediation. Most clean-up decisions have been based either on EPA's Maximum Contaminant Levels (MCL) or so-called 'risk-based' levels. For many chemicals, risk-based levels are much lower than the corresponding MCLs. This paper uses an uncertainty analysis of probability density functions (PDF) to assess whether MCLs are sufficient to provide health protection for human populations using remediated groundwater as the sole tapwater source. A case-study involving tetrachloroethylene and chloroform and all the potentially direct and indirect routes of exposure to contaminated water is presented. The results suggest that groundwater need not be cleaned-up to concentrations less than drinking water standards (i.e., MCLs) to achieve health protection. DIALOG(R)File 41-.Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RISK ASSESSMENT 42 ------- Using Ecological Risk Assessment Methods Williams, Cris TERRA Inc, Tallahassee, FL Environ Prot Jan 94 v5, n1, p56(3) Language: English journal article 7 reference(s) Ecological risk assessments must now be performed in conjunction with human health risk evaluations at Superfund sites. As defined by EPA, these risk assessments will ppraise actual or potential effects of a hazardous waste site on animals and plants. Information needs unique to the ecological assessment include data concerning habitats warranting special emphasis in the assessment. EPA has issued new guidance on ecological risk assessment practices, and additional methodological refinements are anticipated. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Validation of Structure Activity Relationships Used by the USEPA's Office of Pollution Prevention and Toxics for the Environmental Hazard Assessment of Industrial Chemicals Nabholz, J. Vincent EPA, Washington, DC; Clements, R. G.; Zeeman, M.; Osborn, Kimberly C.; Wedge, Roberta ASTM Environ Toxicol & Risk Assess: Aquat, Plant & Terrestrial Symp, Pittsburgh, PA Apr 26-30, 92 p571(20) Language: English Full text available from Congressional Information Service. conf paper 2 graph(s); 13 reference(s); 1 table(s) Under TSCA, the EPA Office of Pollution Prevention & Toxics predicts the aquatic toxicity of industrial chemicals by use of structure-activity relationships (SAR). Validation studies weigh the accuracy of a SAR and entail comparison of predicted with measured toxicity values. The SAR is judged accurate when the two values coincide. The validation process is summarized for neutral organic chemicals, organics which demonstrate excess toxicity relative to neutral organics with similar structure, anionic surfactants, acid dyes, and other chemical families. The importance of accurate toxicity test data for the validation of SARs is stressed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 43 RISK ASSESSMENT ------- Value Assumptions in Risk Assessment: A Case Study of the Alachlor Controversy Lobay, Shelagh M. Journal of Env Law and Practice 2 n3 329-331 July, 1992 LRI File 150 D!ALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. RISK ASSESSMENT 44 ------- HEALTH RISKS GENERAL Assessment and communication of risks from pesticide residues in food Levine, Tina E. Food and Drug Law Journal 47 n2 207-214 March, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. CHEMRISK, a multiple-exposure pathway risk assessment model Temeshy, A.F.; Kneeland, L.R. Bechtel Environmental 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-FA-168.03 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Comparison of radiological risk assessment methods for environmental restoration Dunning, D.E.,Jr.; Peterson, J.M. Argonne Natl. LaD., Argonne, IL Thirty-Eighth Annual Meeting of the Health Physics Society, Atlanta, GA (USA), 11-15 Jul 1993 Williams & Wilkins, 428 E. Preston St., Baltimore, MD 21202, USA, Abstracts, Health Physics - The Radiation Protection Journal, June 1993 Volume 64 Number 6 Supplement 1, ISSN: 0017-9078 Paper No. TAM-D11 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Conceptual structure of performance assessments conducted for the waste isolation pilot plant Helton, J.C.; Marietta, M.G.; Rechard, R.P. Arizona State Univ, Tempe, AZ, USA Proceedings of the 16th International Symposium on the Scientific Basis for Nuclear Waste Management, Boston, MA, USA v 294 1993. Publ by Materials Research Society, Pittsburgh, PA, USA. p 885-898 Language: English 45 RISK ASSESSMENT ------- This presentation describes how the preceding presentation provides a basis in the WIPP PA for (1) the definition of scenarios and the calculation of scenario probabilities and consequences, (2) the separation of subjective and stochastic uncertainties, (3) the construction of the complementary cumulative distribution functions required in comparisons with the U.S. Environmental Protection Agency's standard for the geologic disposal of radioactive waste (i. e., 40 CFR Part 191, Subpart B), and (4) the performance of uncertainty and sensitivity studies. Results obtained in a preliminary PA for the WIPP completed in December of 1991 are used for illustration. (Edited author abstract) 28 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Coping with the risk of cancer in children living near power lines Abt, Eileen N. Risk: Health, Safety & Environment 5 n1 65-74 Wntr, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Dow Scientist Issues Strong Defense of New Method of Calculating Worker Risk/EPA Backs Pharmacokinetic Approach in Estimating Risk for Exposed Workers Occup Saf Health Report-BNA Sep 23 92 v22, n17, p876(3) Language: English Full text available from Congressional Information Service. journal article EPA has endorsed a new method for calculating the cancer risk of methylene chloride. The pharmacokinetic model, which evaluates how a chemical substance is absorbed, metabolized, and eliminated from the body, attempts to explain the physiological differences between laboratory test animals and humans exposed to toxic substances. OSHA has recommended lowering the maximum exposure limit in the workplace from 500 to 25 ppm, which would cost employers approximately $108 million/yr. Using the pharmacokinetic approach would be less costly to employers. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 46 ------- Formation and control of brominated ozone by-products Krasner, Stuart W.; Gramith, Jill T.; Means, Edward G.; Patania, Nancy L.; Najm, Issam N.; Aieta, E. Marco; Montgomery, James M. Metropolitan Water District of Southern California, La Verne, CA, USA Proceedings of the 1991 AWWA Annual Conference, Philadelphia, PA, USA, 1991 Jun 23-27 Language: English The United States Environmental Protection Agency (USEPA) is developing disinfection by-product (DBP) regulations as mandated by the 1986 Safe Drinking Water Act amendments. In addition to potentially lowering the existing trihalomethane (THM) standard, the USEPA may regulate individual THMs and promulgate standards for other DBPs. Other by-products under consideration for regulation include haloacetic acids (HAAs), cyanogen chloride (a DBP associated with the use of chloramines, and bromate (an ozone by-product). Also, the USEPA has established disinfection and filtration criteria for surface-water sources in its Surface Water Treatment Rule (SWTR), which will go into effect in June 1993. Utilities must control pathogenic microorganisms while minimizing the formation of possibly carcinogenic DBPs. For example, some studies indicate that bromate is a possible carcinogen. According to Bull and Kopfler, the 10** minus **4 excess cancer risk (the highest of the range of risk levels associated with maximum contaminant levels) for bromate may be as low as 0.01 mg/L (10 mu g/L). However, a full risk assessment must also consider technological feasibility and economic factors, as well as the practical quantitation limit for a compound of regulatory concern. 22 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Inhalation risk assessment for all power plants in Maryland Birks, A.L. Versar Incorporated 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-TA-36A.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 47 RISK ASSESSMENT ------- Legislating acceptable cancer risk from exposure to toxic chemicals •• Rosenthal, Alon; Gray, George M.; Graham, John D. Ecology Law Quarterly 19 n2 269-362 May, 1992 LRI File 150 DIALOG{R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All its. reserv. Maximum Dosage Level in Testing Low-Toxicity Chemicals for Carcinogenicity in Rodents Apostolou, Alexander; Helton, Edward D. (Sigma-Tau Chemicals, Gaithersburg, MD) J Appl Toxicol May-Jun 93 v13, n3, p209(4) Language: English journal article 39 reference(s) In the interests of following a conservative approach in assessing the Carcinogenicity of chemicals, guidelines formulated during the 1970s and 1980s allowed for the administration of nontoxic chemical amounts up to 5% of the total diet. Since the acceptance of this guideline, studies have shown that such high doses are associated with misleading results that are detrimental rather than helpful in regulating chemical compounds, including those used as human Pharmaceuticals. The case is made for reducing the percentage allowable in diet to 1 %. For compounds tested in drinking water or administered by gavage, a level of 1000 mg/kg/d should oe acceptable. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. A Method for Obtaining Guidance for the Combination of Qualitative Rankings by Cancer and Noncancer Risks into a Single, Qualitative Health Risk Ranking Deisler, Jr. Paul F. Comparative Environ Risk Assessment (Lewis) 1993 p177(21) Language: English Full text available from Congressional Information Service. book chapter 4 graph(s); 2 reference(s); 6 table(s) In a major study EPA ranked its 31 primary problems in terms of cancer risk, noncancer health risk, ecological risk, and welfare risk. To prioritize resources, the author was requested to consolidate these lists into a single health risk ranking of the problems. The principles RISK ASSESSMENT 48 ------- of quantitative ranking are enumerated with respect to this merging-of qualitative rankings. In the model developed, specific pairs of cells containing defined problems are compared to arrive at a final merged ranking. Judgment, rather than calculation, is employed to arrive at the final ranking. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Qualitative and quantitative issues in assessment of neurotoxic effects Sette, W.F.; MacPhail, R.C. Health Eff. Div., Off. Pestic. Programs, US Environ. Prot. Agency, Washington, DC 20460, USA TARGET ORGAN TOXICOLOGY SERIES.; (15), Publ by: RAVEN PRESS, NEW YORK, NY (USA), 1992, pp. 345-361 In NEUROTOXICOLOGY. Tilson, H.A.; Mitchell, C.L. (eds.), 1992 Language: English Book-chapter article Subfile: 24 Toxicology Abstracts; 11 Neurosciences Abstracts The purpose of this chapter is to review several issues that have arisen in the assessment of neurotoxicity data in the Office of Pesticides and Toxic Substances (OPTS) of the Environmental Protection Agency (EPA). Some of these issues are common to many types of target organ toxicity, while others have features particular to the evaluation of effects on the nervous system. Some are issues that have long been debated, while others are now arising in the wake of activities being undertaken to change existing policies. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. Research to improve health risk assessments: Setting the stage for residual risk assessment of the hazardous air pollutants Vandenberg, J.J.; Cote, I.L. U.S. EPA 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-RA-116A.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 49 RISK ASSESSMENT ------- Toxicological basis for drinking water: Unreasonable risk to health •. values Zavaleta, J.O. Drink. Water Health Assess. Sect., Off. Sci. and Technol./Off. Water (WH-586), U.S. Environ. Prot. Agency, 401 M St., SW, Washington, DC 20460-0001, USA 12. Annu. Meet, of the American College of Toxicology;, (np; ) J. AM. COLL. TOXICOL VOL. 11, NO. 3 pp. 325-329 1992 Language: ENGLISH The U.S. Environmental Protection Agency (EPA) administers the Safe Drinking Water Act (SDWA) to ensure that the water obtained from a public water supply is safe to drink. Under the SDWA, EPA establishes enforceable maximum contaminant levels (MCLs) for contaminants that may have an adverse health effect and are known or anticipated to occur in water. Occasionally, public water supplies are unable to meet the MCL at the time it becomes enforceable. The SDWA allows public water supplies to apply to the State for a temporary variance or exemption from an MCL(s) as long as the concentration of the contaminant(s) exceeding the MCL(s) does not result in an unreasonable risk to human health. EPA has developed guidance to assist States in determining what level above the MCL presents an unreasonable health risk. In developing this guidance, the toxicity exhibited by each regulated contaminant is evaluated individually. DIALOG(R)File 41 :Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RISK ASSESSMENT 50 ------- HEALTH RISKS CANCER Carcinogen risk assessment Salmon, A.G. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Environmental risk factors of cancer and their primary prevention Dobrowolski JW, Smyk B Institute of Management and Protection of the Environment, Polish Academy of Sciences, Krakow. J Environ Pathol Toxicol Oncol 1993 Jan-Mar;12(1):55-7 Language: English The evaluation of the influence of different environmental carcinogenic factors requires interdisciplinary cooperation. Related studies include epidemiological surveys and air, water and soil, chemical, toxicological, and microbiological analyses, supplemented by experimental verification of suspected ecological pathogens and cofactors. A balance of carcinogens and protective agents in the external environment and in the human body is recommended for an ecologically oriented prevention. Toxicological control of the food chain using modern technology (Proton-induced X-ray emission (PIXE), nuclear activation analysis, and induced coupled plasma) should be integrated with microanalyses at the cellular level (by X-ray scanning electron microscopy, nuclear magnetic response, PIXE, and spontaneous and delayed chemiluminescence for balance of free-radicals and their scavengers). A pilot cross-disciplinary study conducted in the area of a cluster of human neoplasms and cattle leukemia, in comparison with control villages in Poland, showed an excess in Pb, Hg, Ni, Rb, K, Mn, Cr, and Zn, accompanied by a nutritional deficiency in Mg, Ca, Fe, Co, and Se in the food chain of the cluster. The living and breeding houses in this area were significantly more contaminated with the toxicogenic molds Aspergillus flavus and Penicillium meleagrinum and by nitrate and nitrite in the drinking water. Our experiments showed that selenium deficiency stimulated the growth of fungi and some bacteria and increased the immunosuppressive and teratogenic effects of aflatoxin B1. New methods of protection of the indoor environment against microbiological contamination and 51 RISK ASSESSMENT ------- laser-related biotechnology for nutritional prevention of selenium deficiency and associated risk of neoplasms have been introduced. Primary prevention requires a large scale application of highly sensitive methods for early detection of risk factors in the environment, food, water, and at the personal level, as well as education of the society and an integrated common corrective action. MEDLINE Non-Hodgkin's lymphoma and occupation in Sweden: a registry based analysis Linet MS, Malker HS, Mclaughlin JK, Weiner JA, Blot WJ, Ericsson JL, Fraumeni JF Jr Division of Cancer Etiology, National Cancer Institute, Rockville, Maryland. Br J Ind Med 1993 Jan;50(1):79-84 Language: English Incidence of non-Hodgkin's lymphoma in different employment categories was evaluated from the Swedish Cancer-Environment Registry, which links cancer incidence during 1961 to 1979 with occupational information from the 1960 census. New associations were found for men employed in shoemaking and shoe repair, porcelain and earthenware industries, education, and other white collar occupations. Several findings supported associations found in other countries, including excesses among woodworkers, furniture makers, electric power plant workers, farmers, dairy workers, lorry drivers, and other land transport workers. Risks were not increased among chemists, chemical or rubber manufacturing workers, or petrochemical refinery workers. Caution must be used in drawing causal inferences from these jinked registry data because information on exposure and duration of employment is not available. Nevertheless, this study has suggested new clues to possible occupational determinants of non-Hodgkin's lymphoma. MEDLINE Risk characterization framework for noncancer end points Pierson, T.K.; Hetes, R.G.; Naugle, D.F. Research Triangle Inst., P.O. Box 12194, Research Triangle Park, NC 27709, USA Methodology for Assessing Health Risks from Complex Mixtures in indoor Air, Arlington, VA (USA) ENVIRON. HEALTH PERSPECT VOL. 95 pp. 121-129 1991 Language: ENGLISH The nature of both indoor air exposures and noncancer end points present significant issues for risk characterization. Noncancer end points are multidimensional, affecting various organs, and are assumed RISK ASSESSMENT 52 ------- to have thresholds. Symptoms also vary in severity within a population. In addition to the complexity of noncancer risk assessment, indoor air exposures are typified by the presence of complex mixtures, which further complicates the complex nature of noncancer risk characterization. Most noncancer risk assessment efforts have focused on defining acceptable daily intakes or reference doses (RfD) rather than estimating incidence and severity of the wide range of effects within an exposed population. The risk characterization framework has been developed to accommodate the RfD approach but, more importantly, to address the multidimensional nature of noncancer risk characterization. Newly emerging methods and standard EPA risk assessment guidelines for noncancer effects and complex mixtures were used as guides for developing the framework. Information and data needs have been identified from the framework. Peak, average, and cumulative doses from indoor air exposures are highly dependent on variable indoor air concentrations and affected by time-activity patterns. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Role of chemically induced cell proliferation in carc'mogenesis and its use in health risk assessment Croy RG ENSR Consulting and Engineering, Acton, MA 01720. REVIEW ARTICLE: 91 REFS. Environ Health Perspect 1993 Dec; 101 Suppl 5:289-302 Language: English JOURNAL ARTICLE / REVIEW There is much interest in incorporating knowledge of biological mechanisms of carcinogenesis into assessments of health risks to humans posed by chemicals in the environment. Debate over the soundness of using data from animal bioassays conducted at minimally toxic doses or fractions thereof for predicting cancer risks to humans exposed to much lower doses has stimulated interest in the question of whether genotoxic or mitotic effects predominate in chemical carcinogenesis. Cell division plays a key role at each stage in the evolution of cancer, and it is well documented that increased rates of cell proliferation can escalate the risk of malignancy. This article examines the current understanding of both mechanisms by which chemicals provoke cell proliferation and the contribution of various kinetic patterns of cell proliferation to carcinogenesis. MEDLINE 53 RISK ASSESSMENT ------- HEALTH RISKS GENOTOXICITY AND REPRODUCTIVE EFFECTS Acute and Genetic Toxicity of Municipal Landfill Leachate Schrab, G. E. Texas A&M Univ, College Station; Brown, K. W.; Donrtely, K. C. Water Air Soil Pollut Jul 93 v69, n1-2, p99(14) Language: English Full text available from Congressional Information Service. research article 43 reference(s); 6 table(s) Four samples of leachate from four representative municipal solid waste (MSW) landfills and one groundwater sample from a monitoring well near one of the sites were tested for genetic and acute toxicity. Three bioassays were used for genetic toxicity testing, and one bioassay was used for acute toxicity testing. In addition, the samples were analyzed for chemical content. Acute toxicity was demonstrated by all leachate samples. Three leachate samples were also genotoxic. All samples contained organic compounds. The groundwater specimen and two leachates contained compounds that are listed by EPA as priority pollutants, including chlorinated organics, solvents, and organic acids. Landfills receiving residential wastes were more chemically contaminated than landfills receiving residential and industrial wastes combined. Cancer risk, as estimated from chemical contamination, from the two residential MSW landfills was as high as for leachates from hazardous waste landfills, and from a Superfund codisposal MSW landfill. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Assessment and evaluation of genotoxicity findings TOXBIB/93/149192 Madle S, Lang R Federal Health Office, Max-von-Pettenkofer-lnstitute, Berlin, Germany. Mutat Res; VOL 291, ISS 1, 1993, P87-91 JOURNAL ARTICLE Language: English TOXLINE RISK ASSESSMENT 54 ------- Carcinogenic and reproductive risk assessment under the California . Proposition 65 statute Zeise, L. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Development of a specific-locus assay in the ad-3 region of two-component heterokaryons of Neurospora: a review de Serres FJ Center for Life Sciences and Toxicology, Research Triangle Institute, Research Triangle Park, North Carolina 27709. REVIEW ARTICLE: 55 REFS. Environ Mol Mutagen 1992;20(4):225-45 Language: English In recognition of the need for a more comprehensive data base for genetic risk assessment of human exposure to mutagenic agents in the environment, a model system was developed for specific-locus studies in Neurospora crassa. This lower eukaryotic organism permits the utilization of microbial techniques for recovery of large numbers of specific-locus mutations at two closely linked loci as well as their subsequent genetic analysis. In particular, this assay makes possible exploratory experiments with different environmental mutagens to obtain data on a wide variety of experimental conditions. Such data make it possible to study induction kinetics and mutational spectra in a manner that is not as yet feasible in higher eukaryotic organisms. This specific-locus assay provides a capability that is unique among eukaryotic organisms for the recovery and analysis of genetic damage at 2 closely linked loci. MEDLINE Developmental effects of endocrine-disrupting chemicals in wildlife and humans Colborn T, vom Saal FS, Soto AM W. Alton Jones Foundation, Washington, DC 20037. REVIEW ARTICLE: 142 REFS. Environ Health Perspect 1993 Oct;101(5):378-84 Language: English Large numbers and large quantities of endocrine-disrupting chemicals have been released into the environment since World War II. Many of these chemicals can 55 RISK ASSESSMENT ------- disturb development of the endocrine system and of the organs that respond to endocrine signals in organisms indirectly exposed during prenatal and/or early postnatal life; effects of exposure during development are permanent and irreversible. The risk to the developing organism can also stem from direct exposure of the offspring after birth or hatching. In addition, transgenerational exposure can result from the exposure of the mother to a chemical at any time throughout her life before producing offspring due to persistence of endocrine-disrupting chemicals in body fat, which is mobilized during egg laying or pregnancy and lactation. Mechanisms underlying the disruption of the development of vital systems, such as the endocrine, reproductive, and immune systems, are discussed with reference to wildlife, laboratory animals, and humans. Environmental genotoxicity and cancer risk in humans: a combined evaluation correlating the results of the Tradescantia micronucleus assay in the field and human biomarker assessments in serum. I. The TRAD-MCN assay Sadowska A, Pluygers E, Narkiewicz M, Pawelczak A, Lata B Anti-cancer Plant Laboratory, Warsaw Agricultural University, Poland. Eur J Cancer Prev 1994 Jan;3(1):69-78 Language: English JOURNAL ARTICLE It is well documented that environmental pollution from industrial activity, sewage farms, hazardous waste sites, incinerators, etc, contributes to the overall cancer risk and that this contribution can be considerable under certain circumstances. It is important, therefore, to identify the level of genotoxic activity in the environment and to relate it to biomarkers of cancer risk in humans. After reviewing a range of cytogenetic assays, we have selected the Tradescantia micronucleus assay (TRAD-MCN) developed by Ma et al to be used in indoor and field evaluations. The meiotic pollen mother cells of T clone 4430 are particularly sensitive to chemical pollutants; the buds are exposed for 6-8 h. We describe assays made down wind from a coal-fired power station and from the vicinity of two waste sites. Statistically significant results were obtained at 200 m and 600 m down wind from the power station; higher levels of micronucleus frequencies (MN) were found in foggy rather than dry conditions. Similarly, in the vicinity of two waste sites the MN frequencies were significantly increased in both dry and foggy conditions up to 1.5 km down wind; this was despite previous efforts to rehabilitate the sites. The TRAD-MCN assay is sensitive, reproducible, easy to perform, well standardized, inexpensive and undemanding in equipment. We propose that it be the primary test for genotoxicity evaluation and mapping followed, in suspicious areas, by human biomarker assays. MEDLINE RISK ASSESSMENT 56 ------- Investigation of a spontaneous abortion cluster: lessons learned McDiarmid MA, Breysse P, Lees PS, Curbow B, Kolodner K Department of Environmental Health Sciences, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD. Am J Ind Med 1994 Apr;25(4):463-75 Language: English JOURNAL ARTICLE An investigation of a reported spontaneous abortion excess in an office environment was undertaken employing a multidisciplinary approach, including (1) an epidemiologic/validation step; (2) an industrial hygiene survey, including electromagnetic field measurements and indoor air quality determinations; and (3) a risk perception/risk communication component. This approach was needed because there are numerous chemical and physical agents and psychosocial stressors that may potentially impact the reproductive status of female office workers. Although video display terminals (VDTs) are typically the focus of spontaneous abortion (SAB) investigations, one cannot ignore other stressors in the environment. Magnetic field exposures within a payroll area were determined using a hand-held survey meter and data logging dosimeter. On average, the full shift time-weighted average exposures of workers to extremely low frequency (ELF) magnetic fields in the payroll office area ranged from 1.0 to 5.6 mG. Influencing the investigation's protocol design were the Centers for Disease Control's (CDC's) recent Guidelines for Investigating Clusters of Health Events. Although these guidelines grew primarily out of cancer cluster investigations, we applied them in this instance and found them to be generalizable to reproductive hazards investigations. A spontaneous abortion excess was validated over a 2-year period among 26 women with 32 reproductive events, with rates 1.5-2.5 times the expected, depending on comparison figures used. Lessons learned in the investigation, including the applicability of the CDC's Cluster Investigation Protocol and the enormous importance of risk perception and risk communication, are described. MEDLINE 57 RISK ASSESSMENT ------- HUMAN AND ENVIRONMENTAL EXPOSURE Assessing pesticide exposure for relative risk assessment Krieger, R.I.; Thongsinthusak, T.; Ross, J.H. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Case study: Human health and ecological baseline risk assessment of wastewater reuse for Seattle Metro Logan, L.R.J.; Wu, E.Y. Parametrix 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-TA-36A.02 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. * Distinctions and lessons learned from CERCLA: Using site-specific risk assessment to control remediation costs in the RCRA facility investigation Fishman, B.E. ICF Kaiser Engineers HazMat/lnternational '93: 11th Annual Presentation, Atlantic City, NJ (USA), 9-11 Jun 1993 HAZMAT WORLD; Department of Commerce, International Trade Administration; State of New Jersey Advanstar Exposition, 800 Roosevelt Rd., Build. E, Suite 408, Glen Ellyn, IL 60137-5835, USA; Telephone: (708) 469-3373; Fax: (708) 469-7477, Proceedings, $105.00 plus $10.00 shipping charge Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 58 ------- Environmental risk assessment for determining the priorities Henriques, L. Chem. Eng. and Health, Minist. Econ. Aff., Netherlands ENS '93 - 2nd International Environmental Northern Seas Conference and Exhibition, Stavanger (Norwayh 24-27 Aug 1993 UN IMO; UN Econ Comm Eur; UNEP; UNIDO; CEC; EBRD; CEFIC; EUROMETAUX; EWPCA; EUREKA's Euromar; ESF; OECD; WEC; ISTC; ICC; NEFCO; Helsinki Comm, Baltic Mar Environ Prot Comm; Nord Ind Fund; Oslo & Paris Comms; PIANC; Water Environ Fed USA Pergamon Press (or ENS Secretariat, PO Box 410, N-4001 Stavanger, Norway; Telephone: +47 4 55 81 00; Fax: +47 4 55 05 25), Proceedings, $220.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Exposure and risk assessment of chemicals in food and drinking water Fan, A.M. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Health Advisories for Pesticides Orme, Jennifer; Ohanian, Edward V. EPA, Washington, DC UK Royal Soc of Chemistry: Chemistry Agriculture & Environment 1991 p444(9) Language: English book chapter 8 reference(s); 4 table(s) EPA prepares Health Advisories (HA) for drinking water contaminants when standards cannot be met or are exceeded by a public water supply. The HAs are not federally enforceable but offer technical guidance on many aspects concerning potable water contamination. HA levels are based on data from animal or human studies. EPA has issued HAs for 120 contaminants, including pesticides, inorganics, and munitions, and is preparing HAs for 34 others. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. 59 RISK ASSESSMENT ------- Health risks associated with residential exposure to extremely low .. frequency electromagnetic radiation Lamarine, R.J.; Narad, R.A. Dep. Health and Community Serv., California State Univ., Chico, CA 95929-0505, USA J. COMMUN. HEALTH; 17(5), pp. 291-302, 1992 Language: English Journal article-original research Subfile: 24 Toxicology Abstracts Extremely low frequency electromagnetic radiation has received considerable attention recently as a possible threat to the health of persons living near high tension electric power lines, distribution substations, and even in close proximity to common household electric appliances. Results of epidemiological and laboratory research are examined to assess risks associated with magnetic fields generated by extremely low frequency electromagnetic sources. Health risks associated with such fields include a wide variety of ills ranging from disruption of normal circadian rhythms to childhood cancers. Risk assessment has been particularly difficult to determine in light of an ostensible lack of a dose-response relationship. Current media sensation fueled in part by an equivocal position adopted by the United States Environmental Protection Agency has contributed to the controversy. Recommendations for prudent avoidance of possible dangers are presented along with policy implications concerning health risks associated with magnetic fields. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All its. reserv. Risk assessment and management of chemical contaminants in fishery products consumed in the USA Ahmed FE, Hattis D, Wolke RE, Steinman D Institute of Medicine, National Academy of Sciences, Washington, DC. REVIEW ARTICLE: 93 REFS. J Appl Toxicol 1993 Nov-Dec;13(6):395-410 Language: English JOURNAL ARTICLE / REVIEW In the USA a small proportion of fishery products are contaminated with appreciable amounts of potentially hazardous contaminants. However, risks to consumers are not generally high. Inorganic contaminants with the greatest potential for toxicity are antimony, arsenic, cadmium, lead, mercury, selenium and RISK ASSESSMENT 60 ------- sulfites. Among organic compounds, polychlorinated biphenyls, dioxins, several chlorinated hydrocarbon insecticides, certain processing-related and aquaculture-related contaminants pose potential risks for consumers. Log-normal distributions appear to provide good descriptions of the pattern of variation of contaminant concentrations among different geographic areas, and some contaminants (mostly organic) appear to be much more variable than others. This variability offers a solution for reduction of exposure through restricting the harvest of aquatic organisms from specific sites, and by excluding certain species. It is recommended that: (i) existing State and Federal regulations and environmental monitoring be strengthened and enforced to minimize contamination of the aquatic environment; (ii) a program of shared responsibility be instituted, where Federal agencies develop a set of monitoring and inspection practices and state agencies assume responsibility for primary control, site closures and advisories issue; (iii) research and public education by government agencies and health professionals be expanded to determine actual risks and approaches to manage them; (iv) mandatory labeling be considered for specific contaminants; (v) a better system requiring international agreements be developed in order to minimize the differences among various national regulatory approaches. MEDLINE Risk Assessment/Management Issues in the Environmental Planning of Mines Van Zyl, Dirk (Ed. ); Koval, Marshall (Ed. ); Li, Ta M. (Ed. ), Denver, CO, USA Risk Assessment/Management Issues in the Environmental Planning of Mines Risk Assess Manage Issues Environ Plann Min 1992. Publ by Soc for Mining, Metallurgy & Exploration Inc, Littleton, CO, USA. 207p Language: English This conference proceedings contains 25 papers covering a broad range of subjects in the risk assessment/management arena as presently applied in the mining industry. Topics discussed include risk assessment in mine development, risk assessment/management at Superfund sites, managing environmental compliance, site assessment and environmental audits, risk assessment/management for mine closure, economic risk assessment related to environmental decision making, and some miscellaneous aspects of risk assessment/management. Health risk assessments rely heavily on the probabilistic approach presently promoted by the U.S. Environmental Protection Agency. A number of papers in this volume show how this approach has been applied to a variety of projects. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. 61 RISK ASSESSMENT ------- Risk-based evaluation of ground-water contamination by agricultural. pesticides Varshney, Peeyush; Tim, U. Sunday; Anderson, Carl E. Iowa State Univ, Ames, IA, USA Ground Water v 31 n 3 May-Jun 1993. p 356-362 Language: English The recently completed National Pesticide Survey conducted by the United States Environmental Protection Agency (EPA) has identified the presence of various pesticides in ground water. The detection of pesticides in the nation's ground water has raised concerns for public health which has led resource managers in federal and state agencies to recognize that risk assessment is vital for water quality protection. This paper presents a methodology for risk-based evaluation of ground-water contamination by agricultural pesticides. The methodology utilizes the Risk of Unsaturated/Saturated Transport and Transformation of Chemical Concentrations (RUSTIC) model to provide simulations that yield the probable risks associated with a given pesticide. Risk is expressed in terms of the probability of predicted pesticide mass exceeding its recommended health standards. Three widely used agricultural herbicides, simazine, atrazine, and alachlor, were evaluated using long-term (1960-1986) meteorological data for Ames, Iowa. Results indicate that for a well 8 m deep located 200 m horizontally from a pesticide application area in an alluvial sand and gravel setting, the probability of exceeding the maximum contaminant level (MCL) for simazine is about 35%, whereas it is nearly zero for both atrazine and alachlor. Prudent use of simazine in very susceptible areas is recommended. (Author abstract) 24 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Scientists Urge Senate Panel to Consider Non-Cancer Health Effects of Contamination Environ Report-BNA Apr 2 93 v23, n49, p3077(3) Language: English Full text available from Congressional Information Service. journal article Scientists have urged the US government to pay more attention to the noncancer health risks posed by environmental pollutants. They state that existing pollution-control laws are too limited in focus and recommend that the effects of toxic substances on health be gauged RISK ASSESSMENT 62 ------- according to several factors, including population sensitivity, bioaccumulation properties, and potential exposure pathways. Because little is known about the noncancer health effects of air pollution, cost/benefit analyses of measures to control air pollution are often inaccurate, making it difficult for EPA to set effective air-quality standards under the 1990 Clean Air Act Amendments DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Valdez air health study proven approach to community risk assessment of air toxics emissions Tardiff, R.G.; Baker, S.R. EA Engineering, Science and Technology 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-WA-71.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 63 RISK ASSESSMENT ------- CHEMICAL SPECIFIC RISK ASSESSMENT (ALAR) Alar: the EPA's Mismanagement of an Agricultural Chemical Hathaway, Janet S. Natl Resources Defense Counc, Washington, DC The Pesticide Question: Environ, Economics & Ethics (Chapman & Hall) 1993p337(7) Language: English book chapter 34 reference(s) Alar, a growth regulator widely used by apple growers, had been linked to cancer in numerous animal studies in the 1970s; it was found in nearly 75% of sampled apple juice in 1988 and 1989. Uniroyal, the manufacturer, subsequently stopped domestic sales in 1989, and EPA later made the use of Alar illegal for edible crops. The delay between scientific studies of the risks associated with Alar and the regulation of the chemical is attributed to conflicts between the chemical industry, the scientific community, and regulatory agencies. A 1987 study by the Natl Resources Defense Counc definitively linked exposure to pesticides with health risks in children, igniting a wave of public controversy that eventually resulted in the regulation of Alar. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. (ANHYDROUS HYDROGEN FLUORIDE) Accident prevention and the Clean Air Act Amendments of 1990 with particular reference to anhydrous hydrogen fluoride Kaiser, G.D. Sci. Applic. Int. Corp., 11251 Roger Bacon Dr., McLean, VA 22090, USA PROCESS SAF. PROG VOL. 12, NO. 3 pp. 176-180 1993 Language: ENGLISH The sections of the Clean Air Act Amendments (CAAA) of 1990 that refer to accident prevention are to be found in Title III. Two significant requirements of the CAAA in this respect relate to the responsibilities of the Occupational Safety and Health Administration (OSHA), which has promulgated a new Process Safety Management (PSM) standard and the Environmental Protection Agency (EPA), which at the time of writing, is developing Risk Management Program (RMP) regulations. The focus of this paper is on how the requirements of the CAAA may affect the reasons for RISK ASSESSMENT 64 ------- performing a Quantitative Risk Assessment (QRA) or may affect the results of QRA. In order to limit the discussion, this paper focuses on HF. First, the CAAA requires that the EPA assess the hazards associated with HF: the EPA's current draft report is discussed. Second, a generic assessment of the risks associated with the use of HF is given, with emphasis on alkylation units in refineries. The principal contributors to risk will be listed. Finally, an assessment of OSHA's PSM standard 29 CFR 1910.119, the related requirements of state laws such as California's Risk Management and Prevention Program and the potential requirements of EPA's Risk Management Program will be given, including an assessment of how these requirements may influence quantitative estimates of risk. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. (ARSENIC) Arsenic Risk Assessment Carlson-Lynch, Heather McLaren/Hart Environ Engineering Corp, Portland, ME; Beck, Barbara D.; Boardman, Pamela D. Environ Health Perspec Apr 94 v102, n4, p354(3) Language: English Full text available from Congressional Information Service. journal article 21 reference(s) EPA established a cancer slope factor to estimate carcinogenic potency for arsenic in 1988, which was based on an ecological epidemiology study in Taiwan. The cancer slope factor assumes a linear dose-response relationship, not considering increasing evidence of a sublinear dose-response relationship for low As doses. EPA is currently reviewing the issue of lowering the maximum contaminant level from the current 50 (gr)mg/l by examining literature studies. Two of these studies, which consider the methylation threshold and resulting internal cancers, are critically reviewed. The deficiencies in the reports are discussed. It is argued that mechanistic or more refined epidemiological studies are needed to assess the possible relationship between internal cancers and As ingestion, and that future risk assessments for As consider a sublinear As-induced cancer dose-response relationship. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 65 RISK ASSESSMENT ------- (ARSENIC) Arsenic: Risk assessment for California drinking water standards Brown, J.P. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA(USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. (ARYL COMPOUNDS) Hemoglobin adducts of N-substituted aryl compounds in exposure control and risk assessment Neumann HG, Birner G, Kowallik P, Schutze D, Zwirner-Baier I Institute of Pharmacology and Toxicology, University of Wurzburg, Germany. Environ Health Perspect 1993 Mar;99:65-9 Language: English JOURNAL ARTICLE Arylamines, nitroarenes, and azo dyes yield a common type of metabolite, the nitroarene, which produces a hydrolyzable adduct with protein and is closely related to the critical, ultimate toxic and genotoxic metabolite. The target dose as measured by hemoglobin adducts in erythrocytes reflects not only the actual uptake from the environment but also an individual's capacity for metabolic activation and is therefore an improved dosimeter for human exposure. The usefulness of hemoglobin adducts in molecular epidemiology is now widely recognized. With regard to risk assessment, many questions need to be answered. The described experiments in rats address some of these questions. The relationship between binding to hemoglobin in erythrocytes and to proteins in plasma has been found to vary considerably for a number of diamines. The fraction of hydrolyzable adducts out of the total protein adducts formed also varies in both compartments. This indicates that the kind of circulating metabolites and their availability in different compartments is compound specific. This has to do with the complex pattern of competing metabolic pathways, and the role of N-acetylation and deacetylation is emphasized. An example of nonlinear dose dependence adds to the complexity. Analysis of hemoglobin adducts reveals interesting insights into prevailing pathways, which not only apply to the chemical, but may also be useful to assess an individual's metabolic properties. MEDLINE RISK ASSESSMENT 66 ------- (ASBESTOS) Absolutely green: if asbestos is banned because it's hazardous, what's next? Fire? Samuel, Peter Los Angeles Daily Journal v105 n77 p6 April 21, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All its. reserv. (BENZENE) Benzene Mixtures Raise Health Questions Harper, Carolyn HHS, Atlanta, GA; Faroon, Obaid; Mehlman, Myron Soils Aug-Sep 93 p6(6) Language: English journal article 4 table(s) Gasoline and jet fuels represent a significant source of benzene exposures. Benzene, which is classified as a human carcinogen by the EPA, is often mixed with a number of other chemicals in these fuels. The chemicals commonly found in gasoline and other fuels are tabulated. Benzene is also used as a solvent in the chemical and drug industries. A survey of the overall risks posed by benzene is presented. The majority of exposures to benzene occur through inhalation. The results of tests investigating benzene contamination of ground- and surface waters are discussed. DIALOG(R)File 43:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (BENZENE) Risk of Benzene-Induced Leukemia: a Sensitivity Analysis of the Pliofilm Cohort with Additional Follow-Up and New Exposure Estimates Crump, Kenny S. ICF Kaiser Engineers Inc, Ruston, LA J Toxicol Environ Health Jun 94 v42, n2, p219(24) Language: English Full text available from Congressional Information Service. research article 1 graph(s); 33 reference(s); 5 table(s) A 1984 risk assessment for benzene-induced leukemia that was used by OSHA when it reduced the permissible exposure limit to 1 ppm, and served as the basis for the EPA interim risk unit for benzene, is updated. New risk estimates are derived, based on data from follow-up through 1987 and new exposure estimates for this cohort that account 67 RISK ASSESSMENT ------- for factors not considered in earlier studies. An excess of acute myelocytic or acute monocytic leukemia (AMML) was observed in the cohort of chemical plant workers; a strong dose-response trend was evident for this end-point. Quadratic models predict an additional lifetime risk of benzene-related death from 45 yr of exposure to 1 pprn of 0.020-0.036/1000, while linear dose response models predict risks of 1.6-3.1/1000. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (DDT) Assessing health risks associated with DDT residues in soils in California: A Proposition 65 case study Lowe, J.A.; Jamall, I.S. CH2M HILL, 2485 Natomas Park Drive, Suite 600, Sacramento, CA 95833, USA RISK ANAL VOL. 14, NO. 1 p. 47+ 1994 Language: ENGLISH Population growth in California has increased the pressure to convert agricultural land to commercial, industrial, or residential uses. In the ensuing property transactions, buyers and sellers must address the presence of toxic materials in soils such as pesticides, several of which are known to the State of California to cause cancer under Proposition 65. While this statute does not specifically address soil contaminants, the potential scope of its enforcement is sufficiently broad that owners of former agricultural properties may be obliged to provide warning of exposure to potential buyers, occupants, or construction workers about exposure to residues in soil from pesticide applications. However, Proposition 65 provides no guidance on how to assess exposures to chemicals in soil. The U.S. EPA Risk Assessment Guidance for Superfund (RAGS) provides a method for assessing soil-related exposure pathways that is consistent with the intent of Proposition 65. We have calculated the lifetime average concentrations of DDT in soil corresponding to the no-significant-risk level stipulated under Proposition 65 (1 x 10 super(-5)) for a hypothetical residential exposure scenario. The concentration of DDT in soil corresponding to a no-significant-risk ranges from 7.9-18.8 mg/kg, depending upon which exposure pathways are deemed to be complete for residential land use. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RISK ASSESSMENT 68 ------- (DIBROMOCHLOROPROPANE) Risk Assessment of Dibromochloropropane Anon Shell Oil Co., Houston, TX. Govt Report^ Announcements & Index (GRA&I), Issue 03, 1994 NTIS/AD-A271 228/9, Availability: Document partially illegible., 21 Op This document updates Shell's December 19, 1983, Risk Assessment for 1,2-dibromo-3-chloropropane (DBCP). The health-related data on DBCP are reviewed both from experimental animals and from human studies. A number of new animal studies have been published during the past three years and the results of a substantial epidemiology study are available. The new information reinforces Shell's earlier conclusion that realistic partial lifetime exposure to concentrations of DBCP below 100 ppb in drinking water poses no significant risk of an adverse health effect. Indeed, the very existence of risks to humans who might be exposed to drinking water at these levels is speculative. This summary document describes the process used to arrive at our conclusion. More details are provided in the attached appendices and copies of some unpublished reports are included. (DIISOPROPYL METHYLPHOSPHONATE) Dermal penetration of 14C-labeled diisopropyl methylphosphonate in swine Snodgrass HL, Metker LM Toxicology Division, U.S. Army Environmental Hygiene Agency, Aberdeen Proving Ground, Maryland 21010-5422. J Toxicol Enviroft Health 1992 Aug;36(4):367-76 Language: English JOURNAL ARTICLE Diisopropyl methylphosphonate (DIMP) has been identified as a groundwater contaminant on or near sites of former chemical warfare production facilities. The material is a by-product of GB (or Sarin) manufacture and does not occur naturally in the environment. The present study measured the dermal absorption of 14C-labeled DIMP in swine to establish the basis for estimating health risk from this portal of entry. Yorkshire cross swine were treated by sc injection of labeled DIMP to measure the efficiency of bioelimination. Additional pigs each received a single percutaneous (pc) exposure of 400, 40, or 4 micrograms/cm2 of labeled DIMP. Absorption through 7 d was measured by the appearance of 14C label in the urine and feces. Tissue specimens, collected at necropsy, were assessed for residual radioactivity. The results showed that between 3 and 7% of cutaneous DIMP was absorbed through 7 d. Urinary elimination accounted for about 95% of the absorbed dose in the first 24 h. No significant tissue deposition was observed. Pigs treated by the sc route excreted nearly 100% of the injected material 69 RISK ASSESSMENT ------- demonstrating an extremely efficient metabolic process. It was concluded that humans may be expected to absorb less than 10% of an unoccluded single dermal exposure to DIMP. Absorbed dose would likely be metabolized to isopropyl methylphosphonic acid and excreted primarily in the urine within 24 h. Significant evaporation of the material from the open skin surface would be expected to occur. MEDLINE (DIOXIN) Comparison of Predicted and Observed Dioxin Levels in Fish: Implications for Risk Assessment Naiman, Daniel Q. (Johns Hopkins Univ, Baltimore, MD); LaKind, Judy S. Risk: Issues Health Saf Summer 93 v4, n3, p253(10) Language: English Full text available from Congressional Information Service. research article 3 graph(s); 27 reference(s) Data on dioxin levels in fish in the US, which are used for fish-consumption bans and advisories, come principally from two EPA studies. In one study, dioxin levels were determined by sampling and analysis. In the second study, dioxin levels in fish were predicted from the levels of dioxin entering receiving waters at pulp and paper mills. A comparison is made between the results of the two studies at 104 pulp and paper mill sites, and the discrepancies between observed and predicted concentrations are plotted against the observed concentration for each site. For 41.4% of the sites, the predicted and observed concentrations differ by at least one order of magnitude, and for 10.9% of the sites, the difference is at least two orders of magnitude. Therefore, dioxin contamination in fish should be determined by sampling and analysis, rather than by modeling, if risk assessment and communication are to be reliable. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (DIOXIN) Degradation of polychlorinated dibenzo-p-dioxin and dibenzofuran contaminants in 2,4,5,-T by photoassisted ironcatalyzed hydrogen peroxide Pignatello, J.J.; Huang, L.Q. The Connecticut Agricultural Experiment Station, New Haven, CT, USA Water Research v 27 n 12 Dec 1993. p 1731-1736 RISK ASSESSMENT 70 ------- The objective of this study was to determine the fate of polychlorinated dibenzo-p-dioxin (PCDD) and dibenzofuran (PCDF) contaminants in the herbicide 2,4,5-trichlorophenoxyacetic acid treatment by photoassisted Fe**3** plus -catalyzed hydrogen peroxide oxidation, which is being investigated for waste treatment. The 2,3,7,8-tetra-CDD referred ?toxic equivalent' used in risk assessment was reduced-by 99.9% (U.S. Environmental Protection Agency method) or 99.6% (international method). Dark (Fe**3** plus /H//20//2) treatment was somewhat less effective overall. (Author abstract) 20 refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All its. reserv. (DIOXIN) EPA to reaffirm hazards to health posed by dioxin Noah, T.; Aeppel, T. WALL ST. J VOL. 223, NO. 92 p. A16 1994 Language: ENGLISH In a report scheduled to be released in June, the U.S. Environmental Protection Agency (EPA) will find that there is no evidence that dioxin is any less harmful than previously thought. Officials in the paper, chemical, and solid-waste incineration industries and some scientists have argued for years that health threats posed by dioxin were overblown by environmentalists. But the EPA study, begun several years ago to examine new data on the matter, will reaffirm that dioxin poses a cancer risk to humans. In addition, the report will state that dioxin can have harmful effects on the immune systems and hormone systems of individuals who are exposed to it, and can disrupt human development and reproduction. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. (DIOXIN) Interim Report on Data and Methods for Assessment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Risks to Aquatic Life and Associated Wildlife. Cook PM, Erickson RJ, Spehar RL, Bradbury SP, Ankley GT Environmental Research Lab.-Duluth, MN. Govt Reports Announcements & Index (GRA&I), Issue 18, 1993 NTIS/PB93-202828, 161p In April, 1991 the administrator of the U.S. Environmental Protection Agency (EPA) announced that the Agency would conduct a scientific reassessment of the risk of 71 RISK ASSESSMENT ------- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and similar chemicals, to. human health and the environment. The reassessment plan includes a component on the risks of TCDD to aquatic life and associated wildlife. Research to provide needed exposure and effects information to better characterize these risks was initiated in September 1991. Because the results of the research effort will not be available until June 1995, the interim report was prepared to critically review and evaluate data and models currently available for analyzing TCDD exposure to, and effects • on, aquatic life and wildlife and to identify major uncertainties that limit how well risks can be characterized. The report addresses TCDD exposure to, and bioaccumulation in, aquatic organisms, TCDD toxic effects on aquatic life and wildlife, and aspects of risk characterization to exemplify approaches and applicability of current information. TOXLINE (DIOXINS/FURANS) Dioxins/furans: U.S. EPA ecological risk assessment for land application and disposal methods for paper pulp sludge Rabert, W.; Zeeman, M.; Ahlborg, U.G.; Fiedler, H.; Birnbaum, L.S.; Fingerhut, M.; Clement, R.E.; Giesy, J.P.; Denison, M.; et al. (eds.). U.S. Environ. Prot. Agency, Office Toxic Substances, Health and Environ. Rev. Div., Environ. Effects Branch (TS-796), Washington, DC 20460, USA 11. Int. Symp. on Chlorinated Dioxins and Related Compounds, Research Triangle Park, NC (USA) CHLORINATED DIOXINS AND RELATED COMPOUNDS 1991-1992 pp. 1499-1504 CHEMOSPHERE, VOL. 25, NO. 7-10 1992 Language: ENGLISH Potential risks to terrestrial wildlife were estimated from exposure to 2,3,7,8-TCDD/TCDF in paper pulp sludges applied to or disposed of on land. Comparative risks were assessed for land application uses in forests, mine reclamation, and agriculture, versus other disposal methods. Potential risks to fish and aquatic wildlife were also estimated for runoff from such land uses and disposal sites. The general types of wildlife species predicted as potentially most exposed via eating TCDD/TCDF contaminated prey were terrestrial animals such as shrews, woodcocks, and robins. TCDD/TCDF levels in eggs from several bird species collected from Wisconsin pine plantations amended with such pulp sludges corroborated the transfer of TCDD/TCDF from soil via prey species into avian eggs, particularly robin eggs. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. RISK ASSESSMENT 72 ------- (DIOXINS) EPA Study Points to Health Risks of Dioxins and Similar Compounds Hanson, David Chem Eng News May 30, 94 v72, n22, p13(2) Language: English journal article Drafts of EPA's document on risk assessment have shown that health and environmental risks from dioxins, furans, and PCBs have been clearly demonstrated. Although this information was leaked to the public and has not been confirmed by the EPA, risk assessment experts reviewing the data and industry advocates have already challenged the data used to calculate risks, as well as the experimental methodology which generated the data. The final draft will be published this summer. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (GENERAL) Chemical accident prevention under the Clean Air Act Amendments of 1990 Matthiessen, R.C. U.S. EPA, 401 M St. S.W. (OS-120), Washington, DC 20460, USA PLANT/OPER. PROG VOL. 11, NO. 2 pp. 99-101 1992 Language: ENGLISH The Clean Air Act Amendments of 1990 enacted recently contain provisions for th(? prevention of chemical accidents under Title Ill-Hazardous Air Pollutants. These provisions, approaches with respect to process safety management by the Environmental Protection Agency (EPA), and coordination with OSHA will be discussed. DIALOG(R)File 41 :Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. (GENERAL) Role of quantitative risk assessment in chemical releases and wastewater treatment plant design Henry, L.; Goldenberg, S.; Schettler, J.; Gruwell, G.; Yun, J. Water Environment Federation 65th Annual Conference and Exposition, New Orleans, LA (USA), 20-24 Sep 1992 WEF Conferences and Exposition Department, 601 Wythe St., Alexandria, VA Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 73 RISK ASSESSMENT ------- (GENERAL) Safety/Risk Assessment of Chemicals: Principles, Procedures, and Examples Dourson, Micheal L. (EPA, 'Cincinnati, OH); Lu, Frank C. Int J Occup Med Toxicol Oct-Dec 92 v1, n4, p321(15) Language: English journal article 1 graph(s); 26 reference(s); 2 table(s) The acceptable daily intake (ADI) for chemicals has been established by WHO to allow for the technological use of chemicals while minimizing their potential risks to humans. In the US, this is called the reference dose (RfD), established by EPA. The ADI and RfD procedures are outlined to consider their basic underlying principles. Both procedures involve four basic steps: the relevancy and adequacy of the data, the no-observed-adverse-effect level, the safety or uncertainty factor, and the acceptable daily intakes/reference doses. Each step is detailed, and differences between WHO and EPA methodology are noted. Several pesticides that have been evaluated by the two agencies are tabulated, along with the critical effects, experimental doses, safety/uncertainty factor, and ADI or RfD. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. (HEAVY METALS) Risk Assessment, Metals Emissions and the Clean Air Act Amendments of 1990 Trichon, Morris; Chang, Robert Cottrell Environ Services & Technologies, Branchburg, NJ Univ of Calif/et al 1992 Incineration Conf, Albuquerque, NM May 11-15, 92 p255(5) Language: English Full text available from Congressional Information Service. conf paper 1 graph(s); 14table(s) Under the auspices of Title III of the 1990 Clean Air Act Amendments, 11 heavy metals have been listed as hazardous air pollutants. Accordingly, EPA is now establishing lesser quantity emission rates for the seven metals that pose the greatest health and environmental hazards. The sources most affected by these regulations will be incinerators, smelters, and metal-recycling facilities. Research programs are needed to generate data on the behavior of metals RISK ASSESSMENT 74 ------- throughout the combustion process. Specifically, data on thermodynamics and kinetics of metal transformations are required so behavior can be predicted through mathematical modeling techniques. Approaches for addressing this lack of data are considered. Data are tabulated on the physical properties of antimony, arsenic, beryllium, cadmium, chromium, cobalt, lead, manganese, mercury, nickel, and selenium. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (LEAD) A Comparison of the Integrated Uptake Biokinetic Model to Traditional Risk Assessment Approaches for Environmental Lead Chrostowski, Paul C.; Wheeler, Jennifer A.; Clement Int Corp, Fairfax, VA ASTM STP 1158 Superfund Risk Assessment in Soil Contamination Studies 1992 p151{16) Language: English Full text available from Congressional Information Service. conf paper 2 graph(s); 28 reference(s); 2 table(s) A new approach to calculating exposure to lead in contaminated soil is described and compared with the traditional approach. The EPA-developed Integrated Uptake/Biokinetic Model has two main components: uptake of Pb into the body from various sources, and calculation of a blood Pb level from the uptake. The blood Pb level is combined with dose-response functions to predict the probability of adverse health effects. This approach has been calibrated and validated, incorporates pharmacokinetics, and is relatively unaffected by risk-management decisions. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (LEAD) Risk evaluation of lead in soil ground water at the H. Brown Superfund site in Walker, Michigan Meadows, S.D.; Turnblom, S.M.; Hahne, T.W.; Prendiville, T.J. et al. PRC Environ. Mgt. Inc., 1907 Central Ave., Rm. 204, Los Alamos, NM 87544 ASTM Symposium on Superfund Risk Assessment in Soil Contamination Studies, New Orleans, LA (USAJ620 pp. 245-259 SUPERFUND RISK ASSESSMENT IN SOIL CONTAMINATION STUDIES ASTM, 1916 RACE STREET, PHILADELPHIA, PA 19103 (USA) Language: ENGLISH 75 RISK ASSESSMENT ------- A remedial investigation was conducted at a lead battery recycling -. facility in Walker, Michigan. The soil and groundwater are contaminated with high concentrations of lead. A baseline risk assessment was complicated by the lack of toxicity values for lead. The risk assessment compared on-site concentrations and worker blood levels of lead with concentrations and blood levels shown to results in adverse health effects. The U.S. Environmental Protection Agency Lead Uptake/Biokinetic Model was also used to calculate potential blood lead levels in children on-site and in nearby neighborhoods. On-site exposures for workers, future residents, and workers adjacent to the site were concluded to be unacceptably high. For children in nearby neighborhoods the exposure do not appear to be significant. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. AH rts. reserv. (LEAD) Utilization of uptake biokinetic (UBK) lead model to assess risk in contaminated sites Choudhury, Harlal; Peirano, W. Bruce; Marcus, A.; Elias, R.; Griffin, S.; DeRosa, Christopher T. U.S. Environmental Protection Agency, Cincinnati, OH, USA Symposium of the Superfund Risk Assessment in Soil Contaminantion Studies, New Orleans, LA, USA, 1991 Jan 30-31 Language: English Approaches usually available for the assessment of exposures that occur via water, land and/or air are limited by their ability to integrate multiroute scenarios. Additionally, there are indications that these exposures can differentially affect specific subgroups, each having unique sensitivities to chemical insults. Lead is one of the major toxic contaminants of concern found at approximately 47% of the Suferfund National Priority List (NPL) Sites. Low level exposure to lead has been shown to produce adverse effects on heme metabolism, serum vitamin D levels, mental and physical development of infants and children, and blood pressure in adults. Experimental and epidemiologic studies have indicated that blood lead levels in the range of 10-15 mu g/d l-script, or possibly lower, are likely to produce subclinical toxicity. Since a threshold has not been established it is prudent to assume that, for regulatory purposes, a threshold for lead toxicity does not exist. As an alternate to the traditional reference dose approach, the U.S. EPA has developed the Uptake/Biokinetic Lead Model that provides a means for evaluating the relative contribution of various media to establishing blood lead levels. The model is flexible RISK ASSESSMENT 76 ------- and versatile and predicts mean blood lead levels and population distributions associated with multimedia exposure in children. This allows for the identification of site- and situation-specific abatement strategies based on projected blood lead levels in vulnerable human populations. This paper will present examples of NPL site exposure scenarios for lead and how the UBK lead model may be used for characterization of potential health risks as a result of these exposure scenarios. (Author abstract) 20 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (METHYLMERCURY) Re-Evaluation of the Reference Dose for Methylmercury and Assessment of Current Exposure Levels Stern, Alan H. New Jersey Dep of Environ Protection, Trenton Risk Anal 1993 v13, n3, p355{10) Language: English research article 46 reference(s); 3 table(s) Published data on the effects of exposure to methylmercury are reexamined to evaluate current exposure levels. The current EPA and WHO reference doses are 0.3 and 0.47 (gr)mg/kg/d, respectively. It is argued that the weight of evidence from the various studies indicates that the reference dose for methylmercury may not be adequate to provide a reasonable margin of safety against effects + i in utero + r. While there are still uncertainties, recent studies have suggested a more realistic reference dose of 0.07 (gr)mg/kg/d. Monte Carlo simulation is used to derive a probability distribution of background methylmercury exposure using data on nationwide fish consumption rates and methylmercury levels in seafood. The analysis suggests that women of childbearing age are at risk for exposure to methylmercury at doses higher than the recommended 0.07 (gr)mg/kg/d level. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (MTBE) Health Studies Indicate MTBE Is Safe Gasoline Additive Anderson, Earl V. Chem Eng News Sep 20 93 v71, n38, p9(7) Language: English journal article 2 graph(s); 2 photo(s); 3 table(s) 77 RISK ASSESSMENT ------- During the winter of 1992-93, people around the US complained of.. headaches and various other health problems from exposure to gasoline oxygenated with methyl +i tert + r -butyl ether (MTBE). Complaints about the oxygenate were particularly strong in Alaska. Because MTBE is the principal gasoline oxygenate in the US, opposition to the use of MTBE threatens to destroy EPA's national oxygenated fuel program. Therefore, EPA has sponsored several studies of the health effects of MTBE exposure. Although chronic exposure to high levels of MTBE produced an elevated incidence of tumors in some laboratory animals, overall results indicate that MTBE exposure poses little health risk to humans. The health effects of MTBE exposure have been researched by numerous institutions, including Yale Univ, Rutgers Univ, and various environmental consulting firms; the findings of these studies are described. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. (PCB'S) Emissions from the incineration of nerve agent rockets containing low-level PCBs Mart, C.J.; Henke, C.B. Exxon Res. and Dev. Lab., P.O. Box 2226, Baton Rouge, LA 70821-2226, USA J. ENVIRON. SCI. HEALTH, PART A: ENVIRON. SCI. ENG VOL. A27, NO. 6 pp. 1549-1575 1992 Language: ENGLISH During a recent assessment of the obsolete nerve agent rocket stock-pile, some of the shipping and firing tubes encasing the rockets were found to contain low levels of polychlorinated biphenyls (PCBs) within the tube's fiberglass matrix. In order to determine the environmental and regulatory impacts associated with incineration of these rockets, the Army conducted an incineration test in March 1986, using its existing pilot incineration system. Because the feedrate of PCBs to the incinerator was very low and because the background matrix of the stack gas samples was so complex, the approved EPA analytical procedure was not sensitive enough to demonstrate that the PCB emissions were less than the rates required by the Toxic Substances Control Act (TSCA) regulations. While the regulatory level of PCB emissions could not be demonstrated analytically, a health risk assessment based on ambient concentrations of PCBs from dispersion modeling demonstrated that the PCB emissions do not pose a significant health risk. Emissions of octachlorodibenzo-p-dioxin (OCDD) were detected, but the risk assessment found no significant health risk RISK ASSESSMENT 78 ------- associated with OCDD ambient concentrations. No semivolatile, chlorinated organic compounds were identified in the stack gases, while a number of volatile, chlorinated organic compounds were. Again, no significant health risk was associated with these emissions. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. (PCB'S) Risk Variability from Uniform Soil Remediation Goals for PCBs Labieniec, Paula A. Carnegie Mellon University, Pittsburgh, PA; Dzombak, David A.; Siegrist, Robert L. J Environ Eng-ASCE May-Jun 94 v120, n3, p495(18) Language: English Full text available from Congressional Information Service. journal article 4 diagram(s); 23 reference(s); 7 table(s) A technique for defining the variability of risks associated with the utilization of uniform, concentration-based soil-quality criteria is described. The proposed method is then applied to problems involving PCS contaminated soils. A variant of a soil risk model developed by EPA is used to evaluate risk variability for a range of PCB concentrations in soils. This is done to provide an understanding of the effects of variability on individual risks where uniform cleanup goals are used for PCB-contaminated soils. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, lnŁ. All rts. reserv. (PCB'S) Toxicity equivalency factors for PCBs Barnes, A.; Alford-Stevens, A.; Birnbaum, L.; Kutz, F.W.; Wood, W. Health Effects Res. Lab., Research Triangle Park, NC, USA 12 pp NTIS, SPRINGFIELD, VA (USA) 1991 NTIS Order No.: PB92-113349/GAR. Language: ENGLISH In December 1990 the U.S. Environmental Protection Agency sponsored a workshop to discuss the applicability of an interim "toxicity equivalency factor" (TEF) approach to assessing risks posed by exposures to complex mixtures of polychlorinated biphenyls (PCBs). The group concluded that application of the TEF approach to PCBs would be less straightforward than it was in the case of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs/CDFs). DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. 79 RISK ASSESSMENT ------- (PETROLEUM) Exposure/risk-based corrective action approach for petroleum-contaminated sites Shell Development Co Proceedings of the SPE/EPA Exploration and Production Environmental Conference, San Antonio, TX, USA Proceedings of the SPE/EPA Exploration and Production Environmental Conference Proc SPE EPA Explore Prod Environ Conf 1993. Publ by Society of Petroleum Engineers (SPE), P.O. Box 833836, Richardson, TX, USA. p 403-415 Language: English A practical and easy to use exposure/risk-based methodology for guiding corrective action activities at petroleum contaminated sites has been developed. In this approach, site characterization, assessment of potential beneficial uses, exposure/risk characterization, site prioritization, and selection of corrective action alternatives are integrated into a series of worksheets. These worksheets guide the user through the necessary steps to derive site-specific target clean-up levels and the corresponding appropriate corrective action. The risk characterization activities discussed here focus on exposure to groundwater, which is expected to be the pathway of greatest concern at the majority of petroleum contaminated sites. However, it is not difficult to see how this worksheet based approach can be extended to other pathways. The worksheets comprise a final document that is a valuable tool for regulators, contractors, and responsible parties to consistently prioritize sites and develop corrective action plans. This approach is currently being reviewed by several state agencies. In addition, the approach has been presented to the United States Environmental Protection Agency (EPA), and the American Society for Testing in Materials (ASTM). (Author abstract) refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (POLYCYCLIC AROMATIC HYDROCARBONS) Establishing Generic Remediation Goals for the Polycyclic Aromatic Hydrocarbons: Critical Issues LaGoy, P.K.; Quirk, T.C. OHM Remediation Services Corp, Hopkinton MA Environ Health Perspec Apr 94 v102, n4, p348(5) Language: English Full text available from Congressional Information Service. journal article 25 reference(s); 4 table(s) RISK ASSESSMENT 80 ------- The remediation goals established by many state regulatory agencies for PAHs in soil are often exceeded, which diminishes the overall effectiveness of the goals. A better understanding of the health risks of PAH exposure is needed to determine whether the stated risks are over- or underestimated. The factors that affect the uncertainty of exposure estimates are discussed in terms of soil remediation efforts at hazardous waste sites. Areas considered include the carcinogenic potency of PAH mixture, the inability of EPA analytical methods to account for unreported PAHs in environmental samples, and bioavailability. A preliminary analysis of site-of-contact risks suggests that generic remediation goals for carcinogenic PAHs may be close to 0.001 mg/kg, which is well below even rural background PAH levels. It is recommended that the establishment of cleanup criteria for PAH-contaminated sites be based on both practicality and risk, which have been used for years to establish goals for radionuclides. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. (RADIUM) Radium concentration factors and their use in health and environmental risk assessment Meinhold AF, Hamilton LD Brookhaven National Lab., Upton, NY. Govt Reports Announcements & Index (GRA&I), Issue 17, 1992 NTIS/DE92007601, 13p NTIS Prices: PC A03/MF A01 BNL-45035, CONF-920206-2, Contract AC02-76CH00016 Department of Energy, Washington, DC. Radium is known to be taken up by aquatic animals, and tends to accumulate in bone, shell and exoskeleton. The most common approach to estimating the uptake of a radionuclide by aquatic animals for use in health and environmental risk assessments is the concentration factor method. The concentration factor method relates the concentration of a contaminant in an organism to the concentration in the surrounding water. Site specific data are not usually available, and generic, default values are often used in risk assessment studies. This paper describes the concentration factor method, summarizes some of the variables which may influence the concentration factor for radium, reviews reported concentration factors measured in marine environments and presents concentration factors derived from data collected in a study in coastal Louisiana. The use of generic default values for the concentration factor is also discussed. TOXLINE 81 RISK ASSESSMENT ------- (TRICHLOROETHYLENE) Evaluating the risk of liver cancer in humans exposed to trichloroethylene using physiological models Fisher, J.W.; Allen, B.C. Armstrong Lab., Toxicol. Div., Wright-Patterson Air Force Base, OH 45433, USA RISK ANAL VOL. 13, NO. 1 pp. 87-95 1993 Language: ENGLISH Trichloroethylene (TCE) is a widespread environmental pollutant. TCE is classified as a rodent carcinogen by the U.S. Environmental Protection Agency (EPA). A physiologically based pharmacokinetic (PB-PK) model for mice was used to simulate selected gavage and inhalation bioassays with TCE. Plausible dose-metrics thought to be linked with the mechanism of action for TCE carcinogenesis were selected. These dose-metrics, adjusted to reflect an average amount per day for a lifetime, were metabolism of TCE (AMET, mg/kg/day) and systemic concentration of TCA (AUCTCA, mg/L/day). These dose-metrics were then used in a linearized multistage model to estimate AMET and AUCTCA values that correspond to liver cancer risk of 1 in 1 million in mice. A human PB-PK model for TCE was then used to predict TCE concentrations in drinking water and air that would provide AMET and AUCTCA values equal to the predicted mice AMET and AUCTCA values that correspond to Hver cancer risks of 1 in 1 million. DIALOG(R)File 41 .-Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. (VOC'S) Toxic VOC emissions from a POTW in southern California and associated health risk assessment for a permit to operate Wong, E.; Meuse, J.S.; Vasconcelos, J.J.; Leong, L.Y.C.; Smith, J.E. Water Environment Federation 65th Annual Conference and Exposition, New Orleans, LA (USA), 20-24 Sep 1992 WEF, Conferences and Exposition Department, 601 Wythe St., Alexandria, VA 22314-1994, USA; Telephone: (703) 684-2400, Proceedings, $450.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 82 ------- HAZARDOUS WASTE Air quality modeling and its role in the risk assessment at Valdez, Alaska Catizone, P.A.; Hoffnagle, G.F. TRC Environmental Corp. 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-WA-76.03 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Assessment of Health Risk from Wastes in Three Surface Impoundments Moore, Richard A. EcoTek, Erwin, TN ASTM STP 1158 Superfund Risk Assessment in Soil Contamination Studies 1992p217(14) Language: English Full text available from Congressional information Service. conf paper 1 diagram(s); 3 graph(s); 18 reference(s); 4 table(s) Health risks associated with nonradiological wastes in three settling basins at a nuclear fuel production facility in Tennessee were studied. A hypothetical scenario was developed that assumed long-term exposure to contaminants through daily consumption of well water and future residential use of the site. EPA guidelines for baseline risk assessment were followed, and toxicity data from EPA data bases were used. Noncarcinogenic and carcinogenic risks were determined. Uncertainties associated with the risk-assessment process are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Benefits of probabilistic exposure assessment: three case studies involving 83 RISK ASSESSMENT ------- contaminated air, water, and soil Finley B, Paustenbach D ChemRisk Division, McLaren/Hart Environmental Engineering, Alameda, California 94501. Risk Anal 1994 Feb;14(1):53-73 Language: English JOURNAL ARTICLE Probabilistic risk assessments are enjoying increasing popularity as a tool to characterize the health hazards associated with exposure to chemicals in the environment. Because probabilistic analyses provide much more information to the risk manager than standard point risk estimates, this approach has generally been heralded as one which could significantly improve the conduct of health risk assessments. The primary obstacles to replacing point estimates with probabilistic techniques include a general lack of familiarity with the approach and a lack of regulatory policy and guidance. This paper discusses some of the advantages and disadvantages of the point estimate vs. probabilistic approach. Three case studies are presented which contrast and compare the results of each. The first addresses the risks associated with household exposure to volatile chemicals in tapwater. The second evaluates airborne dioxin emissions which can enter the food-chain. The third illustrates how to derive health-based cleanup levels for dioxin in soil. It is shown that, based on the results of Monte Carlo analyses of probability density functions (PDFs), the point estimate approach required by most regulatory agencies will nearly always overpredict the risk for the 95th percentile person by a factor of up to 5. When the assessment requires consideration of 10 or more exposure variables, the point estimate approach will often predict risks representative of the 99.9th percentile person rather than the 50th or 95th percentile person. This paper recommends a number of data distributions for various exposure variables that we believe are now sufficiently well understood to be used with confidence in most exposure assessments. A list of exposure variables that may require additional research before adequate data distributions can be developed are also discussed. MEDLINE Chemical and radiological risk factors associated with waste from energy production Christensen T, Fuglestvedt J, Benestad C, Ehdwall H, Hansen H, Mustonen R, Stranden E National Institute of Radiation Hygiene, Osteros, Norway. Sci Total Environ 1992 Apr; 114:87-97 Language: English JOURNAL ARTICLE RISK ASSESSMENT 84 ------- We have tried to estimate the toxic potential of waste from nuclear.power plants and from power plants burning fossil fuels. The potential risks have been expressed as 'risk potentials' or 'person equivalents.' These are purely theoretical units and represent only an attempt to quantify the potential impact of different sources and substances on human health. Existing concentration limits for effects on human health are used. The philosophy behind establishing limits for several carcinogenic chemicals is based on a linear dose-effect curve. That is, no lower concentration of no effect exists and one has to accept a certain small risk by accepting the concentration limit. This is in line with the establishment of limits for radiation. Waste products from coal combustion have the highest potential risk among the fossil fuel alternatives. The highest risk is caused by metals, and the fly ash represents the effluent stream giving the largest contribution to the potential risk. The waste from nuclear power production has a lower potential risk than coal if today's limit values re used. If one adjusts the limits for radiation dose and the concentration limit values so that a similar risk is accepted by the limits, nuclear waste seems to have a much higher potential risk than waste from fossil fuel. The possibility that such risk estimates may be used as arguments for safe storage of the different types of waste is discussed. In order to obtain the actual risk from the potential risk, the dispersion of the waste in the environment and its uptake and effects in man have to be taken into account. MEDLINE Chemical stabilization of dewatered sludge, a pilot study and health risk assessment of use as landfill closure/repair material Oliva, C.J.; Mezzacapo, T. Water Environment Federation 65th Annual Conference and Exposition, New Orleans, LA (USA), 20-24 Sep 1992 WEF, Conferences and Exposition Department, 601 Wythe St., Alexandria, VA 22314-1994, USA; Telephone: (703) 684-2400, Proceedings, $450.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Chemicals versus microbials in drinking water. A decision sciences perspective Putnam, Susan W.; Graham, John D. Harvard Sch of Public Health, Boston, MA, USA Journal of the American Water Works Association v 85 n 3 Mar 1993. p 57-61 Language: English Public health interventions aimed at reducing one risk may actually increase another risk. For example, concern is growing about the 85 RISK ASSESSMENT ------- chronic health risks associated with the chemical agents used by many water systems to protect against waterborne microbial disease. Some combination of microbial and chemical risks appears to be unavoidable. Science alone cannot resolve this dilemma, because a value judgment that is sensitive to citizens' attitudes toward risk must be made. To compare health risks, the ultimate health effects need to be expressed in the same unit of measurement. Using an analytical framework called decision analysis, policymakers can analyze risks and attitudes in terms of public health effects, economic cost to society, and consequences for overall quality of life. In the current disinfection regulatory deliberations, the US Environmental Protection Agency (USEPA) is approaching the issue from an economic standpoint, whereas if it were to analyze the issue from a different angle, the relative attractiveness of the regulatory scenarios might be quite different. USEPA's current struggle to weigh the trade-offs involved in setting regulations for disinfectants and their by-products underscores the need for targeted social science research about attitudes toward risk. (Author abstract) 40 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Comparative Assessment of Estimated vs. Actual Emissions and Associated Health Risks from a Modern Municipal Waste Combustor Blanchet, Richard J. Environ Toxicology International Inc, Seattle, WA; Kelly, Kathryn E.; Pascoe, Gary A.; Williams, Phil H. Univ of Calif/effcl 1993 Incineration Conf, Knoxville, TN May 3-7, 93 p543(7) Language: English Full text available from Congressional Information Service. conf paper 14 reference(s); 3 table(s) An 800-tpd municipal solid waste-to-energy facility has been designed and constructed in Spokane, WA. Prior to operation, a risk assessment was conducted, using actual stack emissions to verify the initial estimates of potential public-health risks. The risk assessment was conducted in four steps: data collection and evaluation, toxicity assessment using dose-response data, exposure assessment, and risk characterization. The exposure pathways evaluated were inhalation, soil ingestion, dermal contact with contaminated soil, and ingestion of vegetables. Assessment results indicated that the total carcinogenic risks fell below values currently considered protective of human health by EPA. Highest risk was associated with inhalation. None of the RISK ASSESSMENT 86 ------- chemical doses exceeded the non-carcinogenic toxicity criteria for any of the receptor locations. When actual emissions were compared to estimated pre-operational baseline data, it was found that emissions of PCBs, beryllium, mercury/TCDD, cadmium, chromium, and PAHs were lower, while emissions of arsenic, lead, and nickel were higher. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Comparison of risks from outdoor and indoor exposure to toxic chemicals Wallace, L.A. Atmos. Res. and Exp. Assess. Lab., U.S. EPA, Build. 166, Bicher Rd., Vint Hill Farms Stn., Warrenton, VA 22186-5129, USA Methodology for Assessing Health Risks from Complex Mixtures in Indoor Air, Arlington, VA (USA) ENVIRON. HEALTH PERSPECT, VOL. 95 pp. 7-13 1991 Language: ENGLISH Environmental Protection Agency TEAM {Total Exposure Assessment Measurement) Studies have measured exposures of about 800 persons to 25 volatile organic compounds (VOCs) and exposures of about 300 persons to 32 pesticides. These persons were selected to represent more than 1 million residents of industrial manufacturing cities such as Bayonne and Elizabeth, New Jersey, and Los Angeles, California; cities with light industry, such as Greensboro, North Carolina, and Baltimore, Maryland; rural areas such as Devils Lake, North Dakota; and cities with high pesticide use such as Jacksonville, Florida, as well as low-to-moderate pesticide use such as Springfield, Massachusetts. The TEAM data provide an opportunity to estimate the risks from airborne exposure to a number of suspected carcinogens for a substantial number of persons residing in a wide variety of urban, suburban, and rural areas. DIALOG{R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. Construction of complementary cumulative distribution functions for comparison with the EPA release limits for radioactive waste disposal Helton, Jon C.; luzzolino, Harold J. Arizona State Univ, Tempe, AZ, USA Reliability Engineering & System Safety v 40 n 3 1993. p 277-293 Language: English The US Environmental Protection Agency (EPA) has promulgated a standard for the geologic disposal of radioactive waste (40 CFR 191) that 87 RISK ASSESSMENT ------- requires the construction of a complementary cumulative distribution function (CCDF) that defines the probability of exceeding radionuclide releases of various sizes. Construction of this CCDF involves three interrelated activities: development of scenarios that describe the various disruptions that could occur at a waste disposal site, determination of probabilities for scenarios, and calculation of radionuclide releases for scenarios. The computational procedures being used in the performance assessment for the Waste Isolation Pilot Plant (WIPP) in southeastern New Mexico to bring these three activities together to produce the CCDF in 40 CFR 191 are described and illustrated with results obtained in a recent analysis. (Author abstract) 30 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All its. reserv. A critique of risk modeling and risk assessment of municipal landfills based on U.S. Environmental Protection Agency techniques Chilton, J.; Chilton, K. Bus. Law and Econ. Cent., John M. Olin Sch. Bus., Washington Univ., USA WASTE MANAGE. RES VOL. 10, NO. 6 pp. 505-516 1992 Language: ENGLISH Environmental risks are a growing public concern in America. The threat of contaminated drinking water from municipal solid waste (MSW) landfills is receiving increased attention from citizens and from the United States Environmental Protection Agency (USEPA). Examination of USEPA data collected from MSW landfills reveals approximate risks posed by these landfills. USEPA research suggests that 60% of MSW landfills present less than a 1 in 10 billion risk of cancer incidence. Another 6% pose risks less than 1 in a billion, while 17% present risks less than 1 in a million. This study addresses the USEPA risk assessment techniques and models for estimating MSW landfill risks. USEPA data for toxic constituents of landfill leachate are also analysed in order to better understand the difficulties encountered in estimating landfill risks. The study also presents a brief discussion of public perceptions of risk as they relate to communicating the USEPA landfill model results to those who might be affected. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Determining target cleanup levels. A risk assessment-based decision RISK ASSESSMENT 88 ------- process for contaminated sites Hwang, S. T. Pacific Northwest Lab, Richland, WA, USA Journal of Environmental Science and Health, Part A: Environmental Science and Engineering v 27 n 3 Apr 1992 p 843-861 Language: English This paper presents methodologies for estimating target cleanup levels at Superfund sites. The methodologies follow those in the EPA Superfund risk assessment guideline but are performed in reverse order. This is done to determine cleanup levels that correspond to reference doses for noncarcinogens or to a reference risk level for carcinogens as recommended by the U.S. EPA. The target cleanup levels thus derived should be considered adequate to protect public health when multiple pathways of exposure to contaminants in air, soil, food, and water are possible. The transient nature of contaminant concentrations in soil, subject to change over time due to volatilization, leaching, and other phenomena, is also addressed. An example is given which indicates that when the exposure is attributable predominantly to a single pathway, the calculation needed for estimating the target cleanup levels can be considerably simplified. (Author abstract) 9 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Drilling intrusion probabilities for use in performance assessment for radioactive waste disposal Helton, Jon C. Arizona State Univ, Tempe, AZ, USA Reliability Engineering & System Safety v 40 n 3 1993. p 259-275 Language: English Product integral techniques are used to derive computational procedures to determine probabilities for scenarios resulting from drilling intrusions at geologic disposal facilities for radioactive waste. For these derivations, the occurrence of individual drilling intrusions is assumed to be random in time and space, although the drilling rate is not assumed to be constant or even continuous through time. The use of product integral techniques allows the probability model for drilling intrusions to be initially cast in a very general form involving interval functions and then specialized to nonhomogeneous Poisson processes and ultimately to homogeneous Poisson processes. The resultant computational procedures are illustrated with results for the Waste Isolation Pilot Plant (WIPP) in southeastern New Mexico using the 89 RISK ASSESSMENT ------- maximum drilling rate specified by the US Environmental Protection . Agency (EPA) in its standard for the geologic disposal of radioactive waste (40 CFR 191). (Author abstract) 41 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Earthquake Hazard Associated with Deep Well Injection a Report to the U.S. Environmental Protection Agency Nicholson, Craig; Wesson, Robert L. USGS Bull 1951 1990 (82) Language: English Full text available from Congressional Information Service. fed govt report 22 graph(s); 24 map(s); 143 reference(s); 2 table(s) Earthquakes in Colorado, Texas, New York, and other states have been triggered by deep-well injection of fluid. Most of these incidents are associated with waterflooding operations for secondary recovery of hydrocarbons. These activities often entail large arrays of wells injecting fluids at high pressures into small confined reservoirs with low permeabilities. Waste-disposal wells typically inject at lower pressures into large porous aquifers with high permeabilities. Of the many waste disposal wells in the US, only two have been conclusively shown to be associated with triggering significant adjacent seismicity. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Ecological Investigation of a Hazardous Waste Site, Warner Robins, Georgia Wade, Murray C. (Martin Marietta Energy Systems, Oak Ridge, TN); Billig, Patricia (COM Federal Programs Corp, Denver, CO) Natl Assoc of Environ Professionals 19th Annual Conf Proc, Raleigh, NC May 24-26 93 p595(14) Language: English Full text available from Congressional Information Service. conf paper 2 diagram(s); 3 map(s); 14 reference(s); 1 table(s) EPA has designated Zone 1 of Robins Air Force Base, GA, as a Natl Priorities List Site. Results from a quantitative ecological risk assessment for the area are discussed. The characteristics of the bottomland hardwood forest ecosystem in the area are detailed. This analysis included an evaluation of the hydrology, biology, and wetlands ecology of the region. Hydrology data were gathered, using a wide range RISK ASSESSMENT 90 ------- of procedures, including water level recorders, piezometers, and rainfall collectors. Both aquatic and wildlife biological surveys are described. Risks to human health in the region are examined. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Estimating Risk at a Superfund Site Contaminated with Radiological and Chemical Wastes Temeshy, Andrea Bechtel Natl, Oak Ridge, TN; Liedle, Judith M.; Sims, Lynn M.; Efird, Carl R. ASTM STP 1158 Superfund Risk Assessment in Soil Contamination Studies 1992 p231(14) Language: English Full text available from Congressional Information Service. conf paper 10 reference(s); 4 table(s) A hazardous waste site at the Oak Ridge, TN, reservation is being assessed for carcinogenic and noncarcinogenic risks. Air, groundwater, surface water, and soil are contaminated with radiological and chemical wastes. The methods used to determine potential exposure pathways, chemical exposure concentrations, future radionuclide concentrations, and other aspects are described. Toxicity parameters used to quantify dose-response relationships for carcinogenic and noncarcinogenic contaminants are explained. Exposure and toxicity assessments are incorporated into quantitative risk estimates. The risk from radionuclides and some chemicals exceeds EPA target risk ranges. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Fear and loathing in the siting of hazardous and radioactive waste facilities: a comprehensive approach to a misperceived crisis Gerrard, Michael B. Tulane Law Review 68 n5 1047-1217 May, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Health Hazard Evaluation Report HETA Kaiser EA 91 RISK ASSESSMENT ------- National lost, for Occupational Safety and Health, Cincinnati, OH. Hazard Evaluations and Technical Assistance Branch. Department of Education, Providence, Rhode Island. Govt Reports Announcements & Index (GRA&I), Issue 02, 1994 NTIS/PB94-106994, 36p NTIS Prices: PC A03/MF A01 In response to a request from the Professional Employees Union, Local 2012, an investigation was begun into health and comfort complaints at the Rhode Island Department of Education facility, Providence, Rhode Island. Bulk insulation samples from pipe lagging and the furnace surface contained 30 to 50% chrysotile asbestos. Two of five air samples in the furnace room indicated the presence of airborne asbestos. Paint chip samples from the furnace room contained 0.44 and 2.19% inorganic lead. There were potential exposures to lead and asbestos in basement work areas. The author recommends that specific measures be taken to control lead and asbestos exposures and to remedy other identified conditions. TOXLINE Identification of Tire Leachate Toxicants and a Risk Assessment of Water Quality Effects Using Tire Reefs in Canals Nelson, S. M. ; Mueller, G.; Hemphill D. C. Bull Environ Contam Toxicol Apr 94 v52, n4, p574(8) Language: English Full text available from Congressional Information Service. research article 17 referencels);"*!- table(s) In the freshwater canal fisheries of the southwestern US, used automobile tires have been use effectively to enhance fishery habitat. However, little research has been conducted on the effects of tire leachate on water quality. Toxicity Identification Evaluation procedures developed by EPA were used to assess these effects. Acute 24-h toxicity tests were conducted using both Ceriodaphnia dubia and Pimephales promelas, and LC50 values were determined. Leachates were also treated with sodium thiosulfate or ethylenediamine tetraacetic acid to assess metal toxicity. Results indicated that zinc was present in concentrations that could be toxic, and that cadmium, copper, and lead were above background concentrations. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. In the village square: risk misperception and decisionmaking in the regulation of RISK ASSESSMENT 92 ------- low-level radioactive waste Contreras, Jorge Ecology Law Quarterly 19 n3 481-545 August, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Incineration, Risk Assessment, and the Clean Air Act Nichols, Anne ENVIRON Corp, Princeton, NJ; Washburn, Stephen T.; Li, Wen-Whai Univ of Calif/et al 1993 Incineration Conf, Knoxville, TN May 3-7, 93 p59(4) Language: English Full text available from Congressional Information Service. conf paper 4 reference(s) Under the auspices of the 1990 Clean Air Act Amendments (CAAA), EPA must promulgate health-based emission standards for sources emitting known probable or possible human carcinogens. These standards could have a profound effect on hazardous- and medical-waste incineration facilities. Possible routes that these standards may take are considered, and the currently applied risk-assessment protocol for incinerators is described. The risk-assessment strategy generally consists of three components: characterization of emissions, evaluation of potential human exposures, and quantification of potential health risks. The CAAA*has called for the establishment of a Risk Assessment and Management Commission to consider the most appropriate methods of measuring and describing risks as they pertain to federal regulatory programs. A case study is presented of risk assessment at a municipal solid-waste incinerator located within an urban environment. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Lawn Care Pesticides: Reregistration Falls Further Behind and Exposure Effects Are Uncertain GAO Report RCED-93-80 Apr 93 (43) Language: English Full text available from Congressional Information Service. fed govt report 1 diagram(s); 6 table(s) The use of lawn-care pesticides in the US is increasing, accounting for approximately 70 million Ibs of the total 1.1 billion Ibs of 93 RISK ASSESSMENT ------- conventional pesticides used annually. Under the 1972 amendments to the Federal Insecticide, Fungicide, and Rodenticide Act, EPA is required to reregister older pesticides, including those used on lawns. However, the reregistration process is being seriously delayed: required studies for 12 of the 18 major lawn-care pesticides have been delayed by as much at 4 yr, due mostly to problems in obtaining necessary pesticide data. And even after reregistration, the safety of the pesticides may still be uncertain. There are specific contamination problems for two of the most widely used pesticides-2,4-D and diazinon. It is recommended that EPA more fully explore the health effects of lawn-care pesticides during the risk-assessment process, which should place a high priority on the development of testing and assessment guidelines for post-application exposure. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Non-Occupational Exposures to Pesticides for Residents of Two U.S.. Cities Whitmore, R. W. Research Triangle Institute, Research Triangle Park, NC; Immerman, F. W.; Camann, D. E.; Bond, A. E.; Lewis, R. G.; Schaurn, J. Arch Environ Contam Toxicol Jan 94 v26, n1, p47(13) Language: English Full text available from Congressional Information Service. research article 2 graph(s); 15 reference(s); 15 table(s) As part of EPA's Non-Occupational Pesticide Exposure Study, pesticide exposures were determined in Jacksonville, FL, and Springfield/Chicopee, MA, in winter and spring. Data were collected by questionnaire, personal air monitors, and fixed-site air monitors. In each city, the study population consisted of the civilian, non-institutionalized population aged 16 yr or older. No household occupant was involved in the handling or use of pesticides. Air-sampling results indicated that pesticide levels were generally higher in Jacksonville than in Springfield/Chicopee. The same seven chemicals-chlordane, chlorpyrifos, diazinon, dichlorvos, heptachlor, ortho-phenylphenol, and propoxur-had the highest mean concentrations in each season in both cities. Risk-assessment calculations indicated that the cancer risk due to inhalation was negligible, except for heptachlor and aldrin used to control termites. The extensive sampling data are tabulated. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 94 ------- Preliminary air quality risk assessment for a groundwater treatment.. facility Hurrell, C.P.; Zimmer, R.A. Harding Lawson Associates 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-WA-76.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Risk assessment and air quality at Superfund sites Applehans, P.M.; Zimmer, R.A. Harding Lawson Associates 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-RP-140.05 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Risk assessment and closure of former underground storage tanks site in southern California Alhajjar, B.J.; Bowery, M.H.; Jones, F.A. Geraghty and Miller 1992 Petroleum Hydrocarbons and Organic Chemicals in Ground Water: Prevention, Detection, and Restoration, Houston, TX (USA), 4-6 Nov 1992 American Petroleum Institute; Association of Ground Water Scientists and Engineers, National Ground Water Association (NGWA) NGWA, P.O. Box 182039, Dept. 017, Columbus, OH 43218-2039, USA; Telephone: (614) 761-1711; Fax: (614) 761-3446, Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 95 RISK ASSESSMENT ------- Risk assessment at a Superfund site: A case study Haroun, L.A.; MacDonell, M.M.; Peterson, J.M.; Fingleton, D.J. Argonne Natl. Lab., 9700 South Cass Ave., Argonne, IL 60439, USA ENVIRON. PROF VOL. 14, NO. 3 pp. 238-247 1992 Language: ENGLISH The practical application of U.S. Environmental Protection Agency risk assessment guidance for Superfund sites is described for a risk assessment conducted at a quarry previously used for disposal of wastes from the manufacture of TNT and DNT and the processing of uranium and thorium materials. A site-specific strategy for the conduct of the risk: assessment was developed to accommodate factors specific to this site. The potential carcinogenic and noncarcinogenic risks of radiological and chemical contaminants were estimated for passerby and trespasser scenarios. The exposure pathways evaluated were inhalation of radon gas, exposure to external gamma radiation, inhalation of contaminated airborne dusts, and incidental ingestion of and dermal contact with contaminated surface soil. The carcinogenic risks associated with exposures to the radioactive contaminants at the quarry ranged from 4 x 10 super(-6) to 9 x 10 super(-5), and the risks associated with exposures to the chemical contaminants ranged from 1x10 super(-9) to 7x10 super(-5). The hazard indexes (a measure of the potential for noncarcinogenic health effects) ranged from 0.001 to 18. DIALOG{R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Risk assessment for a proposed regional hazardous waste management facility Brooke, K.L. DRE Environmental Services 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-WA-76.01 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK ASSESSMENT 96 ------- Risk assessment framework of fate and transport models applied to hazardous waste sites Hwang, S.T. Pacific Northwest Lab. 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-RA-116A.05 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Risk of congenital malformations associated with proximity to hazardous waste sites Geschwind SA, Stolwijk JA, Bracken M, Fitzgerald E, Stark A, Olsen C, Melius J Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT. Am J Epidemiol 1992 Jun 1 ;135(11):1197-207 Language: English JOURNAL ARTICLE Concern about environmental pollutants has increased; however, it remains unclear whether chronic exposures to toxic chemicals in the environment occur at doses sufficient to produce adverse health effects in humans. To date, community studies have not adequately addressed this question. In this study, the authors linked two existing data bases of the New York State Department of Health to evaluate the relation between congenital malformations and residential proximity to hazardous waste sites in New York State. A total of 9,313 newborns with congenital malformations and 17,802 healthy controls living in proximity to 590 hazardous waste sites in 1983 and 1984 were evaluated. After the authors controlled for several possible confounding factors, results indicated that maternal proximity to hazardous waste sites may carry a small additional risk of bearing children with congenital malformations (odds ratio (OR) = 1.12, 95% confidence interval (CD 1.06-1.18). Higher malformation rates were associated with both a higher exposure risk (no exposure risk: OR = 1.00; low exposure risk: OR = 1.09, 95% Cl 1.04-1.15; high exposure risk: OR = 1.63, 95% Cl 1.34-1.99) and documentation of off-site chemical leaks (not exposed: OR = 1.00; exposed, but no leaks at site: OR = 1.08, 95% Cl 1.02-1.15; exposed, and leaks found at site: OR = 1.17, 95% Cl 1.08-1.27). The increased rates detected may be important in terms of their public health implications. Further research is necessary to strengthen causal inferences regarding the teratogenicity, of waste site exposure. MEDLINE 97 RISK ASSESSMENT ------- Scheduled risk assessment application for the DoE programs Hasit, Y.J.; Patil, G.B. Roy F. Weston 1993 Federal Environmental Restoration Conference and Exhibition, Washington, DC (USA), 25-27 May 1993 Hazardous Materials Control Resources Institute (HMCRI); Dep. Energy; Dep. Def.; Army Corps Eng.; Dep. Navy; EPA; Bur. Reclam.; Air Force; Nav. Facil. Eng. Command; Dep. Inter.; Agency Toxic Subst. and Dis. Regist. HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Selection of indicator chemicals at hazardous waste sites Hovatter, Patricia S.; Gibson, Robert E. Oak Ridge Natl Lab, Oak Ridge, TN, USA Symposium of the Superfund Risk Assessment in Soil Contaminantion Studies, New Orleans, LA, USA, 1991 Jan 30-31 Language: English The cleanup of hazardous waste sites in the United States is an environmental issue of great concern. The baseline risk assessment, as developed by the U.S. Environmental Protection Agency, is conducted to assist in the development of remedial alternatives for cleanup. The first step in this^ssessment involves the selection of chemicals of concern, those chemicals posing the greatest potential public health risk at the site. This paper presents an approach to the selection process that incorporates a computerized program to perform the routine calculations for a concentration-toxicity screening procedure with additional selection parameters, including frequency of occurrence, comparison to background levels, site-relatedness, and environmental persistence and mobility. This approach to the selection of chemicals of concern streamlines the baseline risk assessment to address only those chemicals posing the greatest risk. (Author abstract) 5 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. RISK ASSESSMENT 98 ------- Strategic analysis study-based approach to integrated risk assessment: Occupational health risks from environmental restoration and waste management activities at Hanford Mahaffey JA, Doctor PG, Buschbom RL, Glantz CS, Daling PM Battelle Pacific Northwest Labs., Richland, WA. Govt Reports Announcements & Index (GRA&I), Issue 22, 1993 NTIS/DE93016577, 86p NTIS Prices: PC A05/MF A01 PNL-8598, Contract AC06-76RL01830 Department of Energy, Washington, DC. The goal of environmental restoration and waste management activities is to reduce public health risks or to delay risks to the future when new technology will be available for improved cleanup solutions. Actions to remediate the wastes on the Hanford Site will entail risks to workers, the public, and the environment that do not currently exist. In some circumstances, remediation activities will create new exposure pathways that are not present without cleanup activities. In addition, cleanup actions will redistribute existing health risks over time and space, and will likely shift health risks to cleanup workers in the short term. This report describes an approach to occupational risk assessment based on the Hanford Strategic Analysis Study and illustrates the approach by comparing worker risks for two options for remediation of N/K fuels, a subcategory of unprocessed irradiated fuels at Hanford. Sponsored by Department of Energy, Washington, DC. Superfund and one community program Pavlova, M.T. *• Emerg. and Remedial Response Div., U.S. EPA-Reg. II, 26 Federal Plaza, New York, NY 10278, USA Methodology of Worker Notification Workshop, Vail, CO (USA) AM. J. IND. MED VOL. 23, NO. 1 pp. 183-189 1993 Language: ENGLISH The U.S. Environmental Protection Agency-Region II conducted a pilot program in risk communication and notification of hazardous waste information at a Superfund site in Toms River, New Jersey. The program was designed to assess the levels of awareness and concern among local citizens and to provide accurate information about health risks associated with potential exposure to environmental contaminants. The purpose of this program was to develop linkages among the community; local, state, and federal governments; industry; health professionals; and educators in dealing with environmental problems. A Community Leaders Network was formed and became actively involved in the program. Following a community needs assessment for risk information, a series 99 RISK ASSESSMENT ------- of fact sheets was developed, pretested, disseminated, and evaluated. The analysis of the program highlights the important lesson of being able to respond to the specific changing dynamics of the community and offers guidelines useful for risk communication in many communities. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Toxicity assessment of hazardous waste at a federal facility Ross, Robert H.; Lu, Po-Yung Oak Ridge Natl Lab, Oak Ridge, TN, USA Symposium of the Superfund Risk Assessment in Soil Contaminantion Studies, New Orleans, LA, USA, 1991 Jan 30-31 Language: English In November 1989 the Department of Energy's facilities in Oak Ridge, Tennessee, collectively known as the Oak Ridge Reservation (ORR), were placed on the National Priorities List (NPL). The result was acceleration of ongoing efforts to identify waste sites and to begin assessing the toxicity of each site. It was soon discovered that assessment efforts were hampered by the lack of U.S. Environmental Protection Agency (U.S. EPA) toxicity values (e.g., Reference Concentrations or slope factors) and related information for many of the contaminants identified at the ORR. A decision was made to derive the missing toxicity values, but only in close collaboration with the U.S. EPA, In conducting similar assessments for the U.S. Army, it became apparent that toxicity assessment is not necessarily site specific and, therefore, lends itself to collaboration among Federal agencies who have responsibilities for hazardous waste cleanup. (Author abstract) 6 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Toxicology of upper aerodigestive tract pollutants Holt GR Department of Otolaryngology-Head and Neck Surgery, University of Texas Health Science Center, San Antonio. Otolaryngol Head Neck Surg 1992 Jun;106(6):655-9 Language: English JOURNAL ARTICLE The field of environmental toxicology has become quite important to the study of environmental health in human beings. The stability of the ecosystem in which we RISK ASSESSMENT 100 ------- live is threatened by the nearly 5 million chemical compounds that have been synthesized worldwide, many of which have real or potentially toxic effects on the environment and on life forms. Four major groups of chemicals-metallic elements, nonmetallic elements, organic compounds and inorganic compounds-have certain agents within them that are known toxins to human beings. Some of these agents have an as yet unknown effect, whereas others have been well characterized. They can be found in the workplace, home, and outdoors, and many are unseen and odorless. In the past, most agents have been described in terms of their carcinogenic potential or major toxic effects on organ systems. It is now likely that the important characterization of some of these agents referrable to the upper aerodigestive tract should be at their receptor sites and identify the very discrete and small effects on these sites and their cumulative effects. The concept of threshold is probably an arbitrary one because to date these discrete effects have not been studied. Susceptibility on an individual basis probably varies from low to high, depending on the patient's immunologic and defense mechanisms and the existence of congenital or acquired risk factors. New attention must be given to more subtle effects on the upper aerodigestive tract (i.e., sinusitis and laryngitis) in view of the potential effects of certain toxic agents on these tissues. MEDLINE Union Officials Question Reasoning for Risk Level of OSHA Health Standards Occup Saf Health Report-BNA Sep 30 92 v22, n18, p1004(2) Language: English Full text available from Congressional Information Service. journal article The OSHA risk-management policy allows workers handling hazardous substances to face a level of cancer risk that is higher than that for the public under some environmental regulations. Union representatives of automobile and construction workers have objected to the OSHA proposal of a permissible exposure limit for methylene chloride at one cancer death per 1000 workers. Depending on the particular law, EPA has set exposure limits of one excess death per million people exposed in some cases. Union officials contend that, at hazardous-waste sites, worker exposures are regulated under the OSHA risk-management policy, while exposure to the general public at the boundary of the waste sites is regulated under more stringent requirements. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 101 RISK ASSESSMENT ------- Using the RESRAD computer code to evaluate human health risks from radionuclides and hazardous chemicals Cheng, J.-J.; Yu, C. Argonne Natl Lab, Argonne, IL, USA Journal of Hazardous Materials v 35 n 3 Dec 1993. p 353-367 Language: English A pathway analysis computer code called RESRAD was developed at Argonne National Laboratory for the U.S. Department of Energy (DOE) for the evaluation of sites contaminated with residual radioactive materials. The DOE and its contractors have used RESRAD to calculate radiation doses and cleanup criteria. Recently, the RESRAD code has been improved so that it can calculate the excess cancer incidence risk from radiation exposure by using the slope factors recommended by the U.S. Environmental Protection Agency. This new feature is discussed in detail in this paper. The method for predicting health risks caused by hazardous chemicals is similar to that for predicting risks caused by radionuclides. The feasibility of applying RESRAD to chemical risk assessment is examined in this paper. The results show that after modification, RESRAD can be used for risk assessment of some classes of hazardous chemicals, for example, metals. Expansion of the RESRAD database to include chemical compounds and the addition of applicable exposure pathways (e.g., inhalation of volatile vapors) will increase RESRAD's capability to handle chemical risk assessments. (Author abstract) 12 Refs. DIALOG(R)Rle 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. RISK ASSESSMENT 102 ------- ECOLOGICAL RISK Adapting ecological risk assessment for ecosystem valuation Suter, G.W. Environ. Sci. Div., Oak Ridge Natl. Lab. AAAS 93-159th National Meeting of the American Association for the Advancement of Science, Boston, MA (USA), 11-16 Feb 1993 AAAS Books, PO Box 753, Waldorf, MD 20604, USA, Abstracts, $25.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Assessing ecological hazard under TSCA: Methods and evaluation of data Smrchek, Jerry; Clements, Richard; Morcock, Robert; Rabert, William United States Environmental Protection Agency, Washington, DC, USA Environmental Toxicology and Risk Assessment, Atlantic City, NJ, USA Language: English The Environmental Effects Branch (EEB) of the United States Environmental Protection Agency (USEPA) evaluates data to assess the potential effects, inherent toxicity, and hazard posed by industrial chemicals to the environment for the Office of Pollution Prevention and Toxics or OPPT (formerly the Office of Toxic Substances or OTS) under the Toxic Substances Control Act (TSCAJ. The regulatory framework of TSCA focuses on data submitted by industry and reviewed by EEB. The review process is critical to assessing the ecotoxicological hazard of existing chemicals (TSCA Section 4), new or Pre-manufacture notice (PMN) chemicals (Section 5), and other potentially hazardous existing chemicals (Sections 6 and 8). EEB developed methods for hazard assessment using a tiered testing scheme, test guidelines, environmental endpoints of concern, and assessment factors. The OPPT testing scheme provides a unified, orderly, consistent, economical, and flexible strategy. It is organized into four tiers, each with several toxicity tests. Tiers increase progressively in complexity, testing costs, and duration of the tests. Decision criteria occur at intervals in the scheme and serve to facilitate making choices on whether to proceed with additional testing or to discontinue testing. OPPT test guidelines are state-of-the-art aquatic and terrestrial test methods used to measure toxicity of industrial chemicals. New guidelines (sediment toxicity tests) are promulgated in response to developments in ecotoxicity research, interest in new testing areas, and Agency needs. The testing scheme and test guidelines are used to assess the 103 RISK ASSESSMENT ------- possible environmental hazard of existing chemicals and new chemicals. Available toxicity data on existing chemicals range from a moderate to a large amount, while limited data usually are available for PMN chemicals. Results of available testing are validated by EEB and incorporated into the hazard assessment. This evaluation identifies qualitative and quantitative effects that may occur from chemical exposure, reports environmental concentrations at which toxic effects may begin to occur, and marshalls arguments to support the analysis. These toxic effect concentrations are used to derive environmental concern levels. For PMN chemicals, assessment factors are used to adjust toxicity data to arrive at environmental concern levels, and to require additional testing to better assess hazard. Concern levels are then compared to predicted exposure concentrations to determine the risk of actually incurring harm, and to obtain a decision on possible regulatory action. (Author abstract) 13 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Assessment of Genetically Engineered Microorganisms Under TSCA: Considerations Prior to Use in Fermentors or Small-Scale Release Sayre, Philip G.; Kough, John L. EPA, Washington, DC ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p65(15) Language: English. Full text available from Congressional Information Service. conf paper 2 diagram(s); 42 reference(s) Under the mandates of TSCA, EPA is charged with assessing the potential ecological risk of genetically engineered microorganism (GEMs), which are used for nitrogen fixation in legumes, waste treatment, bioremediation of toxic chemicals, metal mining, and biomass conversion. Following the submission of a Premanufacture Notification, risk assessments are prepared for both closed systems and intentional environmental releases. GEM risk assessments examine information on microbial recipient taxonomy, biology, and ecological niche. The risk-assessment procedure used by EPA's Office of Toxic Substances is detailed, including identification of the recombinant microorganism, human and environmental hazard evaluation, and exposure. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 104 ------- Bottomland Hardwoods in the Tifton-Vadalia Upland of Georgia: A Conceptual Model for Ecological Risk Assessment Lowrance R, Vellidis G Agricultural Research Service, Tifton, GA. Southeast Watershed Research Lab. Georgia Coastal Plain Experiment Station, Tifton. Dept. of Biological and Agricultural Engineering. Govt Reports Announcements & Index (GRA&I), Issue 24, 1993 NTIS/PB93-234540, 53p NTIS Prices: PC A04/MF A01 Corvallis Environmental Research Lab., OR. The report documents the development of a conceptual model for assessing the ecological risk to the water quality function (WQF) of bottomland hardwood riparian ecosystems (BHRE) in the Tifton-Vidalia upland (TVU) ecoregion of Georgia. Previous research has demonstrated that mature BHRE are essential to maintaining water quality in this portion of the coastal plain. The WQF of these ecosystems is considered an assessment endpoint, an ecosystem function or set of functions that society chooses to value as evidenced by laws, regulations, or common usage. The water quality function of BHRE is at risk because of the ecological and environmental quality effects of a suite of chemical, physical, and biological stressors related to nonpoint source pollution from adjacent land uses, agriculture; the conversion of BHRE to other land uses. Final rept. See also PB93-102192. Prepared in cooperation with Georgia Coastal Plain Experiment Station, Tifton. Dept. of Biological and Agricultural Engineering. Sponsored by Corvallis Environmental Research Lab., OR. TOXLINE Challenge of ecological risk assessment Bretthauer, E.W. Res. and Dev., US Environ. Prot. Agency, Washington, DC, USA ENVIRON. TOXICOL. CHEM VOL. 11, NO. 12 pp. 1661-1662 1992 Annual Review Issue. Language: ENGLISH The opportunities and challenges that face the U.S. Environmental Protection Agency (EPA) and the broad community of environmental scientists are quite diverse. At a basic level, were are all concerned with familiar problems such as water pollution, pesticides, and hazardous wastes. In the past, we have generally approached these problems on a pollutant-by-pollutant and medium-by-medium basis without always fully considering broader environmental quality objectives. At a higher level, the emergence of global ecological issues, such as climate change and biodiversity as highlighted at the recent Earth 105 RISK ASSESSMENT ------- Summit, emphasizes this need for a broader perspective. The EPA is intensifying its efforts to deal effectively with this wide range of ecological problems, and we look forward to continued collaboration with, and scientific contributions from, SETAC. We are placing increased emphasis on using a risk-based approach in establishing priorities, allocating resources, improving the scientific basis for decision-making, and developing the necessary research and guidance for risk assessment of human health and ecological impacts. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. Climate Research for Ecological Monitoring and Assessment: a New England Example Cooter, Ellen J. NOAA, Research Triangle Park, NC; LeDuc, Sharon K.; Truppi, Lawrence Clim Res Dec 31 92 v2, n2, p101(12) Language: English Full text available from Congressional Information Service. research article 7 graph(s); 5 map(s); 34 reference(s); 1 table(s) Ecological assessment of risks attributable to anthropogenic stresses requires the consideration of multiple, often interacting sources of stress across a large number of plant and animal species. In terms of climate research, an ecosystem monitoring program was initiated as a joint EPA/USDA endeavor that consisted of the EPA Environ Monitoring & Asssessment Program Forest Resource Group and the USDA New England Forest Health Monitoring project. Climate applications were directed toward addressing monitoring and assessment issues to forest ecosystems in the six New England states. Climate data sets bearing on several major categories of ecosystem impacts, including those affecting growth, nutrient cycling rates, and leaf and limb damage, were assembled. The research has indicated that traditional statistical summaries, such as contour maps and weighted time-series, must be constructed and interpreted with care for large-scale ecological assessments. The development of disturbance theory requries an explicit statement of the parameters of systems that can respond to disturbance; climatological information must be provided for the variables of disturbance pertinent to these response parameters. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 106 ------- Ecological Hazard Evaluation and Risk Assessment Under EPA's Toxic Substances Control Act (TSCA): an Introduction Zeeman, Maurice; Gilford, James EPA, Washington, DC ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p7(15) Language: English Full text available from Congressional Information Service. conf paper 5 diagram(s); 43 reference(s); 2 table(s) TSCA mandated EPA to collect data and determine ecological and human-health risk for industrial chemicals and genetically engineered microorganisms (GEMs). Impact assessment is determined according to ecological endpoints, which are basic considerations of the potential hazard posed by a chemical or a GEM. The development by EPA's Office of Toxic Substances of the testing program for these chemicals and GEMs is described, including processes for selecting surrogate species, testing guidelines, estimating ecotoxicity, assessment factors and chemical concern levels, exposure assessment, and ecological risk. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Ecological risk assessment framework -- the NAS perspective Barnthouse LW Oak Ridge National Lab., TN. Govt Reports Announcements & Index (GRA&I), Issue 02, 1994 NTIS/DE93015364, 8p NTIS Prices: PC A02/MF A01 CONF-930165-2, Contract AC05-840R21400 Department of Energy, Washington, DC. A Workshop on Ecological Risk Assessment was held on February 26--March 1, 1991, at Airlie House, Warrenton, Virginia. In addition to presentation and discussion of the case study papers, the workshop included breakout sessions to discuss conceptual and technical aspects of ecological risk assessment. A general consensus emerged that an ecological version of the 1983 framework is desirable and feasible. The committee concluded that the 1983 human health framework could be expanded to accomodate both human health and ecological risk assessment. For general applicability to ecological assessments, the 1983 scheme requires augmentation to address some of the interfaces between science and management, primarily because of the need to focus on appropriate questions relevant to applicable environmental law and policy under different circumstances. Specifically, the scheme needs modification to address (1) the influence of legal 107 RISK ASSESSMENT ------- and regulatory considerations on the initial stages of ecological risk assessment and (2) the importance of characterizing ecological risks in terms that are intelligible to risk managers. The committee's opinion is that these augmentations are as important for human health risk assessment as they are for ecological risk assessment. This paper briefly describes the framework recommended by the Committee and compares it to EPA's recently-published Framework for Ecological Risk Assessment. Water Federation Environment specialty conference on how clean is clean, Washington, DC (United States), 10-13 Jan 1993. Sponsored by Department of Energy, Washington, DC. TOXLINE Ecological risk assessment in NPDES permits: Quantitative methods for the calculation of expected risk Warren-Hicks, W.; Parkhurst, B.R.; Cardwell, R.D. Water Environment Federation 66th Annual Conference and Exposition, Anaheim, CA(USA), 3-7 Oct 1993 Water Environment Federation WEF601 Wythe St. Alexandria, VA 22314; ph: (703) 684-2400; fax: (703) 684-2492, Proceedings & full papers Paper No. AC93-056-004 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Ecological risk assessment of a metals-contaminated wetland: Reducing uncertainty Presented at: 2. European Conf. on Ecotoxicology, Amsterdam (Netherlands), 11-15 May 1992 Pascoe, G.A.; Blanchet, R.J.; Under, G. Environ. Toxicol. Int., Inc., 600 Stewart, Suite 700, Seattle, WA 98101. USA SCI. TOTAL ENVIRON.; Suppl. Pts. 1-2, 1993, pp. 1715-1728 In PROCEEDINGS OF THE SECOND EUROPEAN CONFERENCE ON ECOTOXICOLOGY. Sloof, W. de Kruijf, H. (eds.), 1993 Language: English For over 125 years, mining wastes containing arsenic, cadmium, copper, and zinc have contaminated the Clark Fork River in Montana, USA. Mining wastes have partially filled Milltown Reservoir, situated approximately 100 miles (240 km) downstream of major sources of the wastes. Previous studies suggested that benthic invertebrate communities have been impacted by the sediment metals, and trout populations are not at the expected carrying capacity in most sections of the river. An ecological RISK ASSESSMENT 108 ------- risk assessment has been initiated under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) to evaluate impacts of the wastes on terrestrial and aquatic plant and animal species. U.S. EPA has organized the risk assessment through public work groups consisting of representatives of a number of government, university, citizen, and private organizations. The ecological risk assessment focuses on lower trophic levels species and populations in the Milltown Reservoir wetland and riverine environment. Although wildlife surveys have indicated good species diversity and abundance, possible subtle effects on plant and invertebrate species, as well as food chain transfer of metals to trout, have been the primary test objectives. To minimize uncertainty in the assessment and to address anticipated subtle biological effects, field and laboratory studies were instituted to derive site-specific concentration-response information. Studies have included soil and wetland bioassays of earthworms and terrestrial and aquatic vegetation endpoints, in addition to measurements of metals uptake in plants consumed by small mammals and waterfowl. Additional studies on the benthos and geochemistry are nearing completion. Preliminary results of the wetland assessment indicate subtle biological effects at high metals concentrations at major depositional areas. Final results will provide managers with substantial ecotoxicological information to assist in rational decisions for the site. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. Ecological risk assessment procedures and applications to the CERCLA process Friant, S.L. Pacific Northwest Lab., Richland, WA Thirty-Eighth Annual Meeting of the Health Physics Society, Atlanta, GA (USA), 11-15 Jul 1993 Williams & Wilkins, 428 E. Preston St., Baltimore, MD 21202, USA, Abstracts, Health Physics - The Radiation Protection Journal, June 1993 Volume 64 Number 6 Supplement 1, ISSN: 0017-9078 Paper No. MPM-A5 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 109 RISK ASSESSMENT ------- Ecological risk assessment: a scientific perspective Gentile, John H.; Harwell, Mark A.; van der Schalie, William H.; Norton, Susan B.; Rodier, Donald J. U.S. Environmental Protection Agency, Washington, DC, USA Proceedings of the American Chemical Society 204th National Meeting on the Role of Environmental (Ecological) Assessment in the Management of Chemical Pollution, Washington, DC, USA Journal of Hazardous Materials v 35 n 2 Oct 1993. p 241-253 Ecological risk assessment is becoming an increasingly important tool for ranking, assessing, reducing, and managing environmental risks. To provide Agency-wide guidance in this area in the U.S., EPA's Risk Assessment Forum has begun a multi-year guidelines development program. The first step in this program was the publication of the report 'Framework for Ecological Risk assessment' which describes the principles, concepts, terminology, and structure of ecological risk assessments. (Author abstract) 15 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Ecological risk management: Cost of attaining acceptable risk Burris, J.A.; Buckley, S.E. ABB Environmental Services 1993 Federal Environmental Restoration Conference and Exhibition, Washington, DC (USA), 25-27 May 1993 Hazardous Materials Control Resources Institute (HMCRI); Dep. Energy; Dep. Def.; Army Corps Eng.; Dep. Navy; EPA; Bur. Reclam.; Air Force; Nav. Facil. Eng. Command; Dep. Inter.; Agency Toxic Subst. and Dis. Regist. HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA; Telephone: (301) 982-9500; Fax: (301) 220-3870, Proceedings, HMCRI member: $58.50 and non-member: $65.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Ecological Risk Assessment Report, Submerged Quench Incinerator, Task IRA-2, Basin F Liquids Treatment Design. Version 3.0 Anon Woodward-Clyde Consultants, Denver, CO. Govt Reports Announcements & Index (GRA&I), Issue 07, 1994 NTIS/AD-A273 848/2, 92p NTIS Prices: PC A05/MF A01 • RISK ASSESSMENT 110 ------- The objective of this ecological risk assessment is to evaluate the potential impacts of on-site incineration of Basin F liquids. Twenty-nine chemicals were evaluated for potential adverse effects to terrestrial and aquatic wildlife and vegetation on RMA. Based on this assessment, it is concluded that the operation of the submerged quench incinerator poses no quantifiable risks to the wildlife and vegetation. The assessment is divided into the following sections: description of the area - terrestrial and aquatic ecology; contaminants of concern; ecological exposure - description of contaminant transport from incinerator to environment; ecological risk - development of risk criteria, risk characterization; assumptions and uncertainties. (Author). Final rept. TOXLINE Escarpment seeps at Shiprock, New Mexico Anon Jacobs Engineering Group, Inc., Albuquerque, NM. USDOE Albuquerque Operations Office, NM (United States). Uranium Mill Tailings Remedial Action Project Office. Govt Reports Announcements & Index (GRA&I), Issue 12, 1993 NTIS/DE93005953, 274p NTIS Prices: PC A12/MF A03 Contract AC04-91AL62350 The purpose of this report is to characterize the seeps identified at the Shiprock UMTRA Project site during the prelicensing custodial care inspection conducted in December of 1990, to evaluate the relationship between the seeps and uranium processing activities or tailings disposal, and to evaluate the risk posed by the seep water to human health and the environment. The report provides a brief description of the geology, groundwater hydrology, and surface water hydrology. The locations of the seeps and monitor wells are identified, and the water quality of the seeps and groundwater is discussed in the context of past activities at the site. The water quality records for the site are presented in tables and appendices; this information was used in the risk assessment of seep water. TOXLINE A Framework for ecological risk assessment at the EPA: Annual Review Issue Norton, S.B.; Rodier, D.J.; Gentile, J.H.; Schalie, W.H. van der; Wood, W.P.; Slimak, M.W. U.S. EPA Lab., Narragansett, Rl 02592, USA ENVIRON. TOXICOL. CHEM.; 11(12), 1992, pp. 1663-1672, 1992 Language: English Journal article-review Subfile: 24 Toxicology Abstracts; 04 Ecology Abstracts 111 RISK ASSESSMENT ------- Ecological risk assessments evaluate the likelihood of adverse ecological effects caused by stressors related to human activities such as draining of wetlands or release of chemicals. The term stressor is used to describe any chemical, physical, or biological entity that can induce adverse effects on ecological components (i.e., individuals, populations, communities, or ecosystems). In this review article, a historical perspective on ecological risk assessment activities at the U.S. Environmental Protection Agency (EPA) is followed by a discussion of the EPA's "Framework Report," which describes the basic elements for conducting an ecological risk assessment. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All its. reserv. How to design an ecological risk assessment Buchman, M. NOAA/HAZMAT HMC/Superfund '92 - HMCRI's 13th Annual National Conference & Exhibition, Washington, DC (USA), 1-3 Dec 1992 Hazardous Materials Control Resources Institute (HMCRI) HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA; Telephone: (301) 982-9500; and Fax: (301) 220-3870, Proceeding, $58.50 members and $65.00 non-members Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. The lessons of Commencement Bay. A pioneering study in Puget Sound helped advance ecological risk assessment Cirone, P.; Coco, M. U.S. EPA, Reg. No. 10 EPA J VOL. 19, NO. 1 pp. 33-34 1993 Language: ENGLISH The lobes of the glacier that carved Puget Sound thousands of years ago created numerous bays that became natural locations for port cities. Unfortunately, many of these bays then became natural sumps for the accumulation of toxic chemicals that those cities produced. One example is Commencement Bay on the shoreline of Tacoma, Washington. More than 280 point sources, including a pulp mill, petroleum refineries, aluminum processors, sewage treatment plants, and an active ocean port, have polluted Commencement Bay. Many nonpoint sources also drain into it. Concerns about the potential ecological and human health effects of RISK ASSESSMENT 112 ------- hazardous substances in sediments of the nearshore/tidal flats area pf the bay led to its addition, in September 1983, to the National Priorities List (NPL) for cleanup under EPA's Superfund program. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Marine ecological risk assessment at Naval Construction Battalion Center, Davisville, Rhode Island. Phase 1 Munns, W.R.; Mueller, C.; Cobb, D.J.; Gleason, T.R.; Pesch, G.G. TECH. REP. U.S. NAV. OCEAN SYST. CENT 264 pp 1991 NTIS Order No.: AD-A247 832/9/GAR Language: English The Naval Construction Battalion Center (NCBC) in Davisville, Rhode Island, has been the subject of a joint ecological research program by the Navy and Environmental Protection Agency. Allen Harbor, a small embayment of Narragansett Bay adjacent to NCBC, was used to develop research and monitoring methods for ecological risk assessment. Two sites on the National Priorities List were of particular concern: (1) a 15-acre landfill used from 1946 to 1972 for the disposal of such wastes as solvents, PCB-contaminated oils, preservatives, sewage sludge, chromic acid, and construction rubble; and (2) a cement-lined pit that from 1960 to 1974 was the depository of calcium hypochlorite, chloride, and decontaminating solution. Phase I of the study characterizes the ecology, natural resources, sediment, and water quality. A preliminary ecological risk assessment is developed. Exposure to and the effects of contamination are measured at both subtidal and intertidal stations. A T-shaped transect of stations projecting from the mouth of the harbor into Narragansett Bay proper is established to determine if measurable levels of contaminants and effects are reaching the Bay. A series of mid-Narragansett Bay stations provide a reference for comparing effects within Allen Harbor. (Prepared in collaboration with Science Applications International Corporation.). DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. 113 RISK ASSESSMENT ------- Methodology for aquatic ecological risk assessment Parkhurst, B.R.; Warren-Hicks, W.; Cardwell, R.D. Water Environment Federation 66th Annual Conference and Exposition, Anaheim, CA (USA), 3-7 Oct 1993 Water Environment Federation WEF601 Wythe St. Alexandria, VA 22314; ph: (703) 684-2400; fax: (703) 684-2492, Proceedings & full papers Paper No. AC93-056-003 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. The Quotient Method of Ecological Risk Assessment and Modeling Under TSCA: a Review Rodier, D. J.; Mauriello, D. A. EPA, Washington, DC ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p80(12) Language: English Full text available from Congressional Information Service. conf paper 4 diagram(s); 4 graph(s); 16 reference(s) The Quotient Method, which is used by EPA's Office of Toxic Substances, assesses the likelihood of ecological risk from industrial chemicals. The method compares the endpoint or effect concentration to a predicted or measured environmental concentration. Among the limitations of the Quotient Method»are than it does not directly address taxonomic or life-stage sensitivies to a toxic chemical, and it cannot objectively address risks at intermediate quotient levels. While the method can identify a risk to the phytoplankton population, it cannot quantify that risk to higher trophic levels, such as fish. Therefore, simulation models are employed to provide quantitative scenarios that relate effects of measurement endpoints to effects on the assessment endpoint. The various types of ecological risk-assessment models are described. The results of the impact-assessment procedure are communicated through the Tribartite Decision Curve, which shows the probability of a 50% reduction of a population as a function of toxicant concentration. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK ASSESSMENT 114 ------- Terrestrial wildlife exposed to agrochemicals: An ecological risk assessment perspective. Annual Review Issue. Kendall, R.J.; Akerman, J. Inst. Wildl. and Environ. Toxicol., Clemson Univ., Pendleton, SC 29670, USA ENVIRON. TOXICOL. CHEM.; 11(12), pp. 1727-1749, 1992 Language: English Journal article-review Subfile: 24 Toxicology Abstracts; 04 Ecology Abstracts Ecological risk assessment of wildlife exposed to agrochemicals addresses hazard and exposure to at least qualify and attempt to quantify the ecological risk. To accomplish a present-day ecological risk assessment in wildlife toxicology, data must be available from several disciplines: analytical toxicology/environmental chemistry, biochemical toxicology, and wildlife ecology/ecotoxicology. This interdisciplinary approach, essential in wildlife toxicology for the assessment of the chemical effects on the reproduction, health, and well-being of wildlife, makes it difficult to rapidly generate the data necessary for ecological risk assessments. However, as the field has evolved, it has become clear that interdisciplinary cooperation is critical to provide the complex data sets required for the registration and reregistration of pesticide products by the U.S. Environmental Protection Agency. The science of ecological risk assessment for terrestrial wildlife exposed to agrochemicals advanced rapidly during the decade of tflfe 1980s and into the 1990s. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All its. reserv. The Use and Application of QSARs in the Office of Toxic Substances for Ecological Hazard Assessment of New Chemicals Clements, R. G. EPA, Washington, DC; Nabholz, J. V.; Johnson, D. W.; Zeeman, M. ASTM STP 1179 Environ Toxicology & Risk Assessment 1st Symp, Atlantic City, NJ Apr 14-16 91 p56(9) Language: English Full text available from Congressional Information Service. conf paper As mandated by TSCA, EPA has compiled an inventory of more than 80,000 industrial chemicals, which have been evaluated as to their possible environmental and human-health efeects. As part of the chemical-analysis procedure, EPA's Office of Toxic Substances 115 RISK ASSESSMENT ------- determines the quantitative structure-activity relationships (QSARs). for each chemical, which are the relationships among the physicochemical properties of the chemicals and their biological activity. QSARs are applied to three broad categories of industrial organic chemicals: neutral organics that are nonreactive and nonionizable, neutral organics that are reactive and ionizable, and surface active organic compounds. No QSARs are available currently for polyanionic polymers, cationic dyes, acid dyes, inorganic metals, and for most classes of pesticides. The factors used in selecting and evaluating QSARs are delineated. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. RISK ASSESSMENT 116 ------- RISK MANAGEMENT DESCRIBES THE REGULATORY DECISION-MAKING PROCESSES TO CONTROL AND MANAGE RISK ------- This page intentionally left blank. ------- GENERAL PERSPECTIVE Advances in risk assessment and management Lakin, M.L. ICF Kaiser Engineers HazMat International '92 - Hazardous Materials and Environmental Management Conference & Exhibition/International, Atlantic City, NJ (USA), 10-12 Jun 1992 HAZMAT WORLD Tower Conference Management Co., 800 Roosevelt Rd., Build. E, Suite 408, Glen Ellyn, IL 60137-5835, USA; Telephone: (708) 469-3373; Fax: (708) 469-7477, Proceedings, $110.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Future directions and research needs Farland, W.H. Off. Health and Environ. Assess., U.S. EPA, Washington, DC 20460 USA Methodology for Assessing Health Risks from Complex Mixtures in Indoor Air, Arlington, VA (USA) ENVIRON. HEALTH PERSPECT VOL. 95 pp. 131-133 1991 Language: ENGLISH The primary focus of this presentation is to highlight suggested future directions and needs of the U.S. Environmental Protection Agency that formed the core of a report to Congress on assessment and control of indoor air pollution. The five major areas that constitute the current EPA indoor air research strategy are monitoring/building studies; health effects; source characterization/mitigation; health impact/risk assessment; and program management/technology transfer. Additionally, major trends and research needs are discussed, including greater emphasis on noncancer effects and multiple pollutants at low levels and the need for more sensitive measures for detecting adverse health effects to more effectively characterize chemically sensitive individuals and population subgroups. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Harmonizing chemical and radiation risk management Brown, S.L. ENVIRON. SCI. TECHNOL VOL. 26, NO. 12 pp. 2336-2339 1992 Language: ENGLISH 119 RISK MANAGEMENT ------- Risk assessment and risk management for radiation and chemicals have developed within markedly different frameworks. The discordance between these different ways of managing risk was not particularly evident until EPA started treating radiation risks in the same context as chemical risks. Given this disparity, some resolution of the discordance between radiation and chemical risk management is needed. The author describes the radiation and chemical frameworks in more detail and suggests some possible approaches to resolve the discordance between them. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Historical accident data and chemical emergency risk management Glickman, T.S.; Golding, D.; Talcott, F.W. Resources for the Future 1993 Simulation MultiConference, Washington, DC (USA), 29 Mar - 1 Apr 1993 Society for Computer Simulation 1993 Simulation MultiConference c/o SCS, P.O. Box 17900, San Diego, CA 92177; Telephone: (619) 277-3888; Fax: (619) 277-3930, Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Increasing Importance of Risk in Environmental Decision-Making Jaksch, John A.; Geffen, Charlette A. Batelle Pacific Northwest Laboratory, Washington, DC Univ of Calif/et al 1992 Incineration Conf, Albuquerque, NM May 11-15, 92 p249(6) Language: English Full text available from Congressional Information Service. conf paper 13 reference(s) With increasing environmental problems and a shrinking pool of financial resources, efficiency and consistency in determining how pollution problems are approached and managed are becoming extremely important. Within this context, risk assessment and management are playing larger and larger roles in prioritizing pollution problems and establishing acceptable levels of cleanup. The concepts of risk assessment, communication, and management are defined, all of which are used to help society choose more wisely among the range of options available for reducing risk. At the federal level, the Committee on Risk Assessment Methodology of NAS is addressing ways to improve the RISK MANAGEMENT 120 ------- risk-assessment process, which will play an ever increasing role at EPA and other federal agencies in how decisions are made. The problems facing DOE and other federal agencies in cleaning up federal facilities-time constraints, the number of cleanup operations, and cleanup costs-will make risk assessment and management paramount to addressing the myriad of ecological regulations and concerns. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Managing environmental compliance - balancing the risks Dresser, J. F. CH2M Hill, Inc, Portland, OR, USA, Denver, CO, USA Risk Assessment/Management Issues in the Environmental Planning of Mines Risk Assess Manage Issues Environ Plann Min. Pub) by Soc for Mining, Metallurgy & Exploration Inc, Littleton, CO, USA. p 85-89 Language: English Management of environmental compliance has been anecdotally compared to a shooting gallery at a carnival, with the following exception: At the shooting gallery, successfully hitting nine out of ten targets usually brings a reward and recognition of shooting skill; hitting nine out of ten environmental compliance expectations not only brings agency consternation and negative publicity, but the ?gallery' will likely shoot back with stiff fines and possible criminal allegations. Faced with the challenges of the new environmental compliance shooting gallery, corporations and professionals are often left asking themselves, ?How do we (or more appropriately, can we) win at this game?' This paper examines recent federal enforcement statistics and offers several suggestions for coping with the responsibility of managing environmental compliance in the 1990's. (Edited author abstract) 8 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. National survey of drinking water standards and guidelines for chemical contaminants McGeorge, Leslie J.; Krietzman, Sandra J.; Dupuy, Carolyn Jean; Mintz, Bruce Environmental Protection and Energy, Trenton, NJ, USA Journal of the American Water Works Association v 84 n 3 Mar 1992 p 72-76 Language: English 121 RISK MANAGEMENT ------- Many states have become involved in the process of developing drinking water standards or guidelines for contaminants in drinking water. In 1985 the US Environmental Protection Agency (USEPA), in cooperation with a small number of state agencies, formed the Federal-State Toxicology and Regulatory Alliance Committee (FSTRAC). Now, a majority of state drinking water and risk assessment programs have joined the USEPA for the purposes of exchanging information on the risk assessment of drinking water contaminants and improving the coordination of federal and state drinking water risk assessment and standard-setting activities. FSTRAC conducted an extensive survey of the 48 primacy states, Puerto Rico, and the USEPA for information on each drinking water program, including existing and planned standards or guidelines for chemical contaminants as of January 1989. The bases for these standards and guidelines were also requested from each state, as well as an explanation of which factors besides risk assessment (i.e., treatment feasibility, cost) were used in the standard-setting process. (Author abstract) 8 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. The New Air Toxics Program Claiborne, Margaret L. Hunton & Williams, Washington, DC Nat Resour Environ Fall 92 v7, n2, p21(6) Language: English Full text available from Congressional Information Service. journal article * The 1990 Clean Air Act Amendments contain hazardous air pollutant regulations that expand the existing air toxics program. The regulations identify 189 toxic air pollutants that must be addressed by the program. Listed chemicals will be subject to technology-based emission standards, rather than health-based standards. The standards will require the maximum degree of emission reduction on the basis of the best technology currently available. EPA must also report to Congress on the public health risks that remain after control technologies have been implemented. The agency must adopt residual risk-based standards if any source presents a cancer risk to a specific number of individuals. Key development areas that need scrutiny are identified, such as the definition of "source," source categories, and the implementation of maximum achievable control technology. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. RISK MANAGEMENT 122 ------- New focus on air toxics Boutacoff, D. EPRIJ, VOL. 16, NO. 2, pp. 4-13 1991 Language: ENGLISH New amendments to the federal Clean Air Act include provisions to reduce emissions of airborne toxic substances considered to pose a risk to human health or the environment. While the petrochemical and metals industries are the primary focus of the new air toxics provisions, some of these substances-mercury and nickel, for example-have been identified as present in fossil plant flue gas. The legislation calls for the Environmental Protection Agency to conduct a three-year study of the potential health risks specific to utility sources, after which the EPA administrator will decide whether controls are needed for power plants. To complement the EPA research and help utilities prepare for all possible outcomes, EPRI is developing methods to predict how fuel type and plant configuration affect levels of air toxics emissions, is studying how these substances are chemically converted after leaving the plant, and is assessing the risk they pose to public health and the environment. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. Stop Superfund Waste Reilly, Bernard J. E. I. du Pont de Nemours Co, Wilmington, DE Issues Sci Technol Spring 93 v9, n3, p57{7) Language: English Full text available from Congressional Information Service. journal article CERCLA's Superfund program was designed as a $1.6-billion program to clean up a limited number of the nation's most dangerous abandoned toxic-waste sites. It has evolved into an attempt to transform thousands of sites to near-pristine conditions. Cost estimates for clean up of these sites now range from $32-150 billion. Most of the effort and money are directed to a relatively small number of priority sites, while others are ignored and not even studied. The problems of assigning risk and liability, and allocating tax money to the Superfund program are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 123 RISK MANAGEMENT ------- Total exposure assessment in occupational epidemiology for risk management Jedrychowski W, Maugeri U, Jedrychowska-Bianchi I Department of Epidemiology and Preventive Medicine, University Medical School, Cracow, Poland. G Ital Med Lav; VOL 13, ISS 1-6, 1991, P27-33 JOURNAL ARTICLE Language: English Exposure assessment is an integral and essential component of occupational epidemiology necessary for risk assessment, risk management as well as for diagnostic and intervention efforts. It is a multidisciplinary approach that usually requires the combined expertise of environmental and industrial hygienists, toxicologists, epidemiologists, physicians, social scientists and statisticians. Exposure-assessment methodology employs various direct and indirect techniques, including environmental measurements, personal monitoring, biological markers, questionnaires, and mathematical modelling. Exposure assessments for occupational environment must be considered in the framework of potential contributions from other media and adding the incremental exposure from other media when necessary. Furthermore, to achieve effective risk assessment, all media and routes of exposure must be assessed for the relative magnitude of their contributions before an assessment of one medium is conducted. In the paper the concept of total human exposure assessment is introduced and measurement approaches have been discussed focusing attention on environmental research surveys. TOXLINE RISK MANAGEMENT 124 ------- RISK MANAGEMENT GUIDELINES AND POLICY Army Material Command environmental risk management program Talts, A.; Jonhson, M.F.; Anderson, K.E. U.S. Army Material Command 1993 Federal Environmental Restoration Conference and Exhibition, Washington, DC (USA), 25-27 May 1993 Hazardous Materials Control Resources Institute (HMCRI); Dep. Energy; Dep. Def.; Army Corps Eng.; Dep. Navy; EPA; Bur. Reclam.; Air Force; Nav. Facil. Eng. Command; Dep. Inter.; Agency Toxic Subst. and Dis. Regist. HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA; Telephone: (301) 982-9500; Fax: (301) 220-3870, Proceedings, HMCRI member: $58.50 and non-member: $65.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. EPA Looks at Superfund Reform Means, Bruce; Cooper, David EPA, Washington, DC Health Environ Dig Jun 94 v8, n3, p3(2) Language: English Full text available from Congressional Information Service. journal article <• The Superfund Reform Act (SRA), which will reauthorize the Superfund program, should clarify hazardous waste cleanup goals. Among the issues SRA will address are use of risk assessment for determining the need for remedial action, the role of decision-making criteria besides cleanup results, and expectations about risk levels allowed after cleanup. The importance of assessing ecological risks, in addition to public health risks, is noted. Cleanup costs should be considered in screening out remedies for which an equally effective but cheaper alternative is available. SRA would create a standardized risk assessment protocol to make decision-making more consistent and more equitable across sites. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 125 RISK MANAGEMENT ------- EPA priorities for biologic markers research in environmental health . Fowle, J.R.,111; Sexton, K. Office Health Res., U.S. EPA, Washington, DC 20460, USA ENVIRON. HEALTH PERSPECT.; 98, pp. 235-241, 1992 Language: English Journal article-original research Subfile: 24 Toxicology Abstracts Recent advances in molecular and cellular biology allow for measurement of biologic events or substances that may provide markers of exposure, effect, or susceptibility in humans. The application of these new and emerging techniques to environmental health offers the possibility of significantly reducing the uncertainties that traditionally hamper risk assessments. The U.S. Environmental Protection Agency (EPA) health research program emphasizes the validation of appropriate biologic markers and their application to high-priority Agency issues. The rationale for EPA's biomarker research program is presented, and future research directions are discussed. Exposure biomarkers will receive most of the research emphasis in the near term, particularly body burden indicators of exposure to high-priority chemicals, such as benzene, ozone, selected heavy metals, and organophosphate pesticides. Research on effects biomarkers will attempt to validate the relationship between the observed biological effects and adverse health consequences in humans, especially for cancer, pulmonary toxicity, immunotoxicity, and reproductive/developmental toxicity. DIALOG(R)File 76:Life Sciences Collection (c) 1994 Cambridge Sci Abs. All rts. reserv. EPA toxic substances program: Long-standing information planning problems must be addressed 36 pp 1993 Government Accounting Office, WASHINGTON, DC (USA) Language: ENGLISH Because toxic chemicals are in such widespread use today, nearly every American's body contains traces of toxic chemicals as a result of skin absorption or other environmental exposure. Some of the chemicals, such as asbestos, PCPs, and ozone-depleting chemicals, have been found to cause tumors and birth defects as well as to harm wildlife. The Environmental Protection Agency (EPA) is responsible for identifying, assessing, and regulating the risks posed by the approximately 72,000 chemicals in commercial use as well as chemicals proposed for manufacture. Because of concerns about EPA's information resources management practices, this report examines whether EPA is effectively RISK MANAGEMENT 126 ------- planning for and using information resources to (1) identify and assess chemicals posing the greatest risk to human health and the environment and (2) retrieve critical data on health and environmental risks by other federal users that assess risks from chemicals. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Health and chemical environment in Czecho-Slovakia, international cooperation context Trnovec T, Rosival L Institute of Preventive and Clinical Medicine, Bratislava, Czecho-Slovakia, CSFR. REVIEW ARTICLE: 11 REFS. Regul Toxicol Pharmacol 1993 Feb;17(1):66-76 Language: English This review provides a record of the present situation with regard to public health and environmental degradation and its underlying causes in Czecho-Slovakia, taking into account ways of life, which is a synonym for its two components: environment and behavior. It gives attention to the priorities which include air and water pollution and food contamination. Environmental protection includes the human health protection from air, water, land, and groundwater pollution, ecological protection and natural resource preservation, use of pesticides, food and consumer product safety, and safety associated with the introduction of new chemicals into commerce. Further, this review focuses on the fundamental building blocks for a new environmental policy and management system (Constitution Act, 1991; Environmental Law, 1991; Chemical Act, in preparation; standards regarding chemicals, etc.)l»With regard to the international concern about the dangers of chemicals for humanity and the natural environment, attention is drawn to the collaboration of Czecho-Slovakia in chemical safety with WHO, IRPTC, and OECD. An important task is to determine what scientific research is needed and to educate administrators, politicians, and the general public in chemical safety. MEDLINE How to Move Quickly to Risk-Based Environmental Management: a Specific Proposal Garetz, William V. EPA, Washington, DC Comparative Environ Risk Assessment (Lewis) 1993 p279(28) Language: English Full text available from Congressional Information Service. book chapter 7 diagram(s); 2 reference(s) The EPA trend toward risk-based management is moving forward despite criticisms of risk assessment techniques. It is argued that even faulty 127 RISK MANAGEMENT ------- techniques offer enough data to improve the management process, .and this is illustrated through the development of a risk-based decision-making process. This process ultimately assigns resources to the cost-effective options, regardless of the absolute risk of the problem. Resources are also allocated to developing better risk-assessment databases and risk reduction technologies. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Impact of EPA regulatory and policy initiatives on risk management and waste disposal strategies for the mining industry Faison, G.; Pavlou, S.; Borden, R.; Leftwich, T.; Pavlich, K. Ebasco Environmental, Bellevue, WA, USA, Denver, CO, USA Risk Assessment/Management Issues in the Environmental Planning of Mines Risk Assess Manage Issues Environ Plann Min. Publ by Soc for Mining, Metallurgy & Exploration inc, Littleton, CO, USA. p 33-36 Language: English Recent regulatory and policy initiatives under the Resource Conservation and Recovery Act (RCRA), and the Comprehensive Environmental Response Compensation and Liability Act (CERCLA), will have a significant effect in risk reduction requirements for the mining and minerals processing industry. For example, Congress is considering regulating 20 special wastes from the processing of ore and minerals through RCRA Subtitle D and TSCA. The performance of risk analyses and environmental planning at mining projects is often driven by Federal and state regulatory standards. Recent regulatory and policy initiatives by the Environmental Protection Agency under the Resource Conservation and Recovery Act (RCRA), and the Comprehensive Environmental Response Compensation and Liability Act (CERCLA), will have a significant effect on environmental planning and risk reduction programs for mining and minerals processing. Regulatory programs implemented under other Federal laws including the Safe Drinking Water Act, Clean Water Act, and Clean Air Act will also impact industry practices. This paper provides: 1) a brief overview of mining waste and mining waste management, and 2) a description of these regulatory initiatives and a discussion on the impacts of new requirements on environmental and risk reduction programs in the mining industry. (Author abstract) 7 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. RISK MANAGEMENT 128 ------- New approaches in setting drinking water standards Ohanian, E.V. Off, Sci. Technol./Off. Water (WH-586), U.S. Environ. Prot. Agency, 401 M St., S.W., Washington, DC 20460-0001, USA 12. Annu. Meet, of the American College of Toxicology;, (np; ) J. AM. COLL. TOXICOL, VOL. 11, NO. 3 pp. 321-324 1992 Language: ENGLISH The Safe Drinking Water Act Amendments of 1986 required that the U.S. Environmental Protection Agency (EPA) establish standards for 83 contaminants by June 1989, and at least 25 added standards by January 1991, then 25 more every three years hence. Conceptually, the regulatory process employed by EPA consists of two steps. First, a detailed health risk assessment of a contaminant is performed in order to determine the Maximum Contaminant Level Goal (nonenforceable health goal) in water that should result in no known or anticipated health effects and allows adequate margin of safety. Second, the results of risk assessment and management (taking best available technology, treatment techniques, cost, and other means into consideration) are combined to derive the Maximum Contaminant Level (enforceable standard) which is set as close to the MCLG as feasible. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. OSHA Nearing Completion of Options Paper for New Administration, Official Tells Panel Occup Saf Health Report-BNA Feb 17 93 v22, n37, p1625(1) Language: English Full text available from Congressional Information Service. journal article An OSHA options paper that addresses the potential health hazards from poor indoor air quality and environmental tobacco smoke (ETS) is nearing completion. The regulation of ETS has come to the fore since EPA identified secondhand smoke as a known human carcinogen. The paper will suggest possible OSHA regulatory options to address indoor air quality and ETS, either together or separately. The agency plans to adapt risk assessments on secondhand smoke for exposure in residential settings to on-the-job risks. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 129 RISK MANAGEMENT ------- OSHA's interest in risk management and accident prevention Seymour, T.H. U.S. DOL-OSHA 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-FA-168.05 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Permitting and compliance programs for toxic discharges Galya, Donald ENSR Consulting & Engineering Power Engineering (Barrington, Illinois) v 96 n 2 Feb 1992 p 35-37 Language: English The Environmental Protection Agency's (EPA) increased emphasis on controlling toxic wastewater discharges probably will result in more stringent permit requirements. However, industry can achieve reasonable permit limits with minimal disruptions to operations through a creative permitting and toxics compliance program. Several techniques for modeling, permitting, monitoring and toxics reduction offer dischargers flexibility in developing a toxics program. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Proceedings of the American Chemical Society 204th National Meeting on the Role of Environmental (Ecological) Assessment in the Management of Chemical Pollution Gabel, Norman W. (Ed.); Gushee, David E. (Ed.) N.W. Gabel & Assoc., Landover, MD, USA Proceedings of the American Chemical Society 204th National Meeting on the Role of Environmental (Ecological) Assessment in the Management of Chemical Pollution, Washington, DC, USA Journal of Hazardous Materials v 35 n 2 Oct 1993. Publ by Elsevier Science Publishers B.V., Amsterdam, Neth. 339p Language: English This issue of the journal contains 14 papers on environmental impact assessment of chemical industry pollution. Topics discussed include the main features of the Endangered Species Act of 1973, the EPA's responsibilities for administering ecological regulations, corporate RISK MANAGEMENT 130 ------- environmentalism, environmental assessment in new drug applications, requirements of the FDA for the environmental assessment of animal health products, protecting cultural resources in managing chemical pollution, a scientific perspective on ecological risk assessment, using toxicity data to evaluate ecological effects at Superfund sites, environmental biomarkers as indicators of chemical exposure, and the use of physical and chemical properties to assess environmental transport and fate. All papers are indexed and abstracted separately. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All its. reserv. Progress report on EPA's 33/50 Program: Reducing toxic risks through voluntary action Anon. TOTAL QUAL. ENVIRON. MANAGE VOL 1, NO. 2 pp. 159-166 1992 Language: ENGLISH EPA's 33/50 Program calls for voluntary industry reductions of toxic wastes, aimed at achieving an overall national reduction of 33 percent by 1992 and 50 percent by 1995. The seventeen high-priority toxic chemicals included in the program accounted for 1.4 bHIion pounds of releases and transfers in 1988; a 50-percent reduction would eliminate 700 million by 1995. As of June 1991, 236 companies have committed to an average reduction commitment of more than 200 million pounds. Thousands more companies are being invited to participate. DIALOG(R)File 41:Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. RCRA at a Crossroads: Whether to Regulate Hazardous Waste Based on Risk or Technological Controls Kastner, Kenneth M. Bryan Cave, Washington, DC Environ Report-BNA Jun 4 93 v24, n5, p247(7) Language: English Full text available from Congressional Information Service. fed govt report 62 reference(s) In interpreting the regulations authorized by RCRA, EPA must determine whether stringent controls should be applied to wastes that do not pose a substantial risk to human or environmental health. Legal, historical, and policy analyses of this issue conclude that a risk-based regulatory structure is most feasible. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 131 RISK MANAGEMENT ------- Reducing risk: Priorities and strategies for environmental protection > Loehr, R. C. U. of Texas SPE Annual Technical Conference and Exhibition - 1992, Washington, DC, USA, 1992 Oct4-7 Language: English In late 1990, the USEPA - Science Advisory Board (SAB) completed a major report for the EPA Administrator and the report recommendations have resulted in policy changes in EPA. A key component of the report is the identification of relative environmental risk and the need to focus on environmental problems of greatest risk. This paper discusses the background and rationale of the report, how the recommendations have been implemented within EPA, and the potential impact to the petroleum production and refining industry. (Author abstract) 9 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Regulating the introduction of new chemicals under section 5 of TSCA: improving the efficiency of the process and reducing potential injury in the workplace through the use of operational MSDS and exposure limits Rosenthal I, Jayjock MA, Keener RL, Plamondon JE Safety Health and Environmental Affairs Department, Rohm and Haas Company, Bristol, PA. Qual Assur 1991 Oct;1(1):10-30 Language: English JOURNAL ARTICLE The Toxic Substances Control Act (TSCA) authorizes the EPA to take appropriate actions to ensure that new and existing chemicals do not pose unreasonable risk to health or the environment. Section 2{b)(3) of the Act directs the Agency to accomplish this objective in a manner that does not impede unduly or create unnecessary economic barriers to technological innovation. In recent years, critics have felt that the EPA has failed to achieve these primary goals of TSCA. This paper considers some of the reasons for this criticism and advocates an alternate approach of exposure limits and operationally sufficient controls to assist in achieving these goals. An illustration of how this alternate approach might work under practical conditions is presented, using as an example a new chemical substance from the class of acrylate monomers. These concepts and risk assessments provide data for a better design of future studies according to good laboratory practice and quality assurance. RISK MANAGEMENT 132 ------- Regulation of Environmental Contaminants in Drinking Water: State Methods and Problems Sidhu, Kirpal S. Michigan Dep Public Health, Lansing J Am Coll Toxicol 1992 v11, n3f p331(10) Language: English journal article 34 reference(s); 1 table(s) States generally accept EPA guidelines for contaminants in drinking water. These are the maximum contaminant levels that are enforceable under EPA regulations. Slightly more than half the states have the personnel and resources to formulate their own guidelines. In cases of imminent risk to human health, a state may have to set an interim guideline, and sometimes the data available to make these decisions is limited. The derivation of state guidelines for carcinogenic and noncarcinogenic contaminants is reviewed, and demonstrated for methyl isobutyl ketone, + i t + r -butyl alcohol, 1,1-dichloroethane, tetrahydrofuran, and carbon disulfide. The risk from exposure by routes other than ingestion, and the derivation of guidelines for exposure to trichloroethylene during bathing is shown. The enforceability of state guidelines, and the expense of implementing state regulations are briefly reviewed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Regulation of existing chemicals under TSCA: information disclosure as the route to reducing risk and increasing available data Rosenthal I, Weiler ED, Keener RL, Cumberland PJ Rohm and Haas Company, Philadelphia, Pennsylvania 19105. Qual Assur; VOL 1, ISS 2, 1992, P89-96 JOURNAL ARTICLE Language: English The Toxic Substances Control Act (TSCA) empowers the Environmental Protection Agency (EPA) to regulate risk associated with the use of existing chemicals and the introduction of new chemicals into commerce. Due to a number of concerns, however, the authority to regulate existing chemicals under TSCA has enjoyed limited success. A more generic and flexible approach is needed to achieve significant risk reduction for existing chemicals. This paper presents a frame-work for a generic approach to the regulation of existing chemicals. Under this framework, EPA would officially recognize that the distribution of chemical substances without evaluating and communicating to the user how to avoid operationally undesirable exposures represents an unreasonable risk to health or the environment. Acting under the authority of TSCA, EPA would then generically 133 RISK MANAGEMENT ------- require suppliers to communicate acceptable exposure levels and information regarding safe use. This framework is consistent with the express policy of TSCA, which states that development of data with respect to the effects of chemical substances and mixtures on health and the environment should be the responsibility of manufacturers and processors of chemicals. The approach outlined here is consistent with and complements initiatives of the Office of Toxic Substances (OTS) and would enable OTS to accomplish some of the fundamental goals of TSCA. TOXLINE Regulatory and institutional considerations in the application of ecological risk assessment at federal facilities Bilyard, G.R.; Bascietto, J.J.; Beckert, H. Pacific Northwest Lab. FED. FACIL. ENVIRON. J VOL. 4, NO. 3 pp. 337-348 1993 Language: ENGLISH The U.S. Environmental Protection Agency (EPA) is developing policies, guidelines, and methodologies for conducting ecological risk assessments. These assessments can be used by federal agencies to help meet their regulatory and institutional obligations during remediation, restoration, closure, or mission changes. This article identifies the regulatory requirements and institutional considerations that could be supported by ecological risk assessments and proposes a process for using ecological risk assessment at government facilities. If adopted, ecological risk assessments have substantial benefits because they would help ensure that a standard analytical process is used throughout the federal system to assess potential impacts to ecological resources; they would ensure, whenever possible, that quantitative data are used to make environmental management decisions; and as discussed in this article, they could be conducted in conjunction with human health risk assessments. , . OIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. Regulatory Problems Associated with Natural Products and Biopesticides Plimmer, Jack R. ABC Laboratories, Columbia, MO Pestic Sci 1993 v39, p103(6) Language: English Full text available from Congressional Information Service. journal article RISK MANAGEMENT 134 ------- Issues surrounding the regulation of natural product and biorational. pesticides in the US are addressed. Juvenile hormones, semiochemicals, and other biopesticides offer new approaches to pest control and the benefits of reduced adverse environmental and health impacts, but acceptance of these options has been slow. Regulatory requirements for establishment of hazard and tolerance levels are viewed as onerous. Progress in molecular biology and related disciplines constrain capabilities of regulators responsible for rendering safety assessments. EPA policy changes that will help streamline and facilitate biorationals registration are recommended. DIALOG(R)File 40:Enviroline{R) (c) 1994 CIS, Inc. All its. reserv. Risk assessment and risk management of noncriteria pollutants LeeSD Environmental Criteria and Assessment Office, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711. Toxicol Ind Health; VOL 6, ISS 5, 1990, P245-55 JOURNAL ARTICLE Language: English Noncriteria air pollutants are synonymous with hazardous air pollutants (HAPs), air toxics or toxic air pollutants (TA term noncriteria pollutants refers to all air pollutants except for the criteria pollutants (SOx, PM, NOx, CO, 03, and Pb). Air toxics are pervasive in our environment worldwide in varying degrees. There are more than 70,000 chemicals that are in use commercially in the United States, and we know relatively little about their ambient concentrations,persistence, transport and transformation as well as their effects on health and the environment, many of which take decades to emerge. The United States Environmental Protection Agency, under the authority of Section 112 of the Clean Air Act, is mandated to regulate any air pollutant which, in the Administrator's judgment, causes, or contributes to, air pollution which may reasonably be anticipated to result in an increase in serious irreversible or incapacitating reversible illness. For such regulatory decision-making, EPA's Office of Health and Environmental Assessment (OHEA) provides scientific assessment of health effects for potentially hazardous air pollutants. In accordance with risk assessment guidelines developed by OHEA over the years, Health Assessment Documents (HADs) containing risk assessment information were prepared and were subjected to critical review and careful revision to produce Final Draft HADs which serve as scientific databases for regulatory decision-making by the Office of Air Quality Planning and Standards (OAQPS) in its risk management process. TOXLINE 135 RISK MANAGEMENT ------- The risks of fixing the current federal system of risk assessment Environmental Forum 11 n2 48(2) March-April, 1994 LFU File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Transaction screening is a useful risk management tool, (part 1) (environmental due diligence) Bennett, Mark J.; Buonicore, Anthony J. Los Angeles Daily Journal v105 n223 p7 Nov 13, 1992 LRI File 150 EDITION: Fri 24 col in DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. The Utility of Environmental Fate Models to Regulatory Programs Callahan, Michael A. EPA, Washington, DC Principles & Practices for Petroleum Contaminated Soils (Lewis) 1993 341(8) Language: English conf paper 1 diagram(s); 14 reference(s); 3 table(s) Environmental fate models can help decision-makers understand some of the factors involved in regulatory decisions. The relationships among risk management, risk assessment, exposure assessment, and environmental fate are examined and their role in the regulatory process is discussed. Fate models serve as a predictive tool for estimating present and potential exposures. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Wastes: Toxic Substances Control Act Hinds, Richard de C. Cleary, Gottleib, Steen & Hamilton, Washington, DC; Weller, Janet L.; Butvinik, Jeffrey I. Environ Law Practice Guide (Matthew Bender) 1992 v3, n27, p27-1(83) Language: English book chapter 328 reference(s) Presented is a thorough and complete review of the Toxic Substances Control Act of 1976, which has control of all chemical production and transport in conjunction with the other applicable statutory mandates RISK MANAGEMENT 136 ------- as determined by the Clean Water Act and Clean Air Act. EPA has . jurisdiction over the implementation, application, and enforcement of all strictures and regulations established by the law. Included are chapter explanations, supported by case law precedents, and those administrative mechanisms associated with the authority of EPA. In addition, risk assessment evaluations are mandated, by which subsequent control over commerce can be initiated prior to possible infractions. Public health issues permeate the various facets of risk assessment actions and are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. When Is a Life Too Costly to Save? The Evidence from Environmental Regulations Van Houtven, George L. {East Carolina University, Greenville); Cropper, Maureen L. (University of Maryland, College Park) Resour (Resour Future) Winter 94 1qr n114, p6(5) Language: English Full text available from Congressional Information Service. journal article 1 graph(s) Some environmental laws require EPA to balance costs and benefits in issuing regulations, but other laws prohibit such balancing. A study of various regulations-including those for asbestos under TSCA, cancer-causing pesticides used on food crops under the Federal Insecticide, Fungicide, and Rodenticide Act, and national emissions standards under the Clean Air Act-show that generally, regulations do consider both costs and benefits. Two issues are examined: how the value of a life implicit in environmental regulations compares with society's apparent willingness to pay to save lives; and the way in which the implicit value of a life seems to vary across EPA programs and across population groups. The value EPA attaches to preventing one cancer case seems very high-from $15-45 million, which is much higher than individuals seem willing to spend. EPA has issued more stringent regulations under statutes that require balancing of costs and benefits than under statutes requiring consideration of health risks only. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 137 RISK MANAGEMENT ------- LEGAL ASPECTS Environmental concerns prompt Section's activity. (Section of Natural Resources, Energy and Environmental Law) (ABA/NYC) Erisman, Frank National Law Journal v15 n49 pS1 August 9, 1993 LRI File 150 EDITION: Mon 28 col in DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Federal Appeals Court Upholds Regulations, Finds Agency Properly Set Contaminant Levels Environ Report-BNA Aug 28 92 v23, n18, p1275(2) Language: English Full text available from Congressional Information Service. journal article The US Court of Appeals for the District of Columbia has upheld EPA regulations on drinking-water contaminant limits. The petitions that were filed by the Int Fabricare Inst, oil and chemical companies, and trade associations had charged that the Natl Primary Drinking Water Regulations were flawed in terms of the contaminant levels set for 1,2-dibromo-chloropropane, ethylene dibromide, tetrachloroethylene, and PCBs. The maximum contaminant levels (MCLs) established by EPA set the amounts of a given contaminant that may be present in water delivered to any public water system user. The court dismissed the challenge because the claimants could not cite any new data supporting the zero MCLs for these contaminants. The substance-specific challenges offered during the proceedings are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Lender liability and environmental risk management Griggs, Malcolm D. Florida Bar Journal 67 n11 80(5) Dec, 1993 LRI File 150 RISK MANAGEMENT 138 ------- More Good Than Harm: a First Principle for Environmental Agencies .and Reviewing Courts Warren, Edward W. Kirkland & Ellis, Washington, DC; Merchant, Gary E. Ecol Law Quart 1993 v20, n3, p379(62) Language: English Full text available from Congressional Information Service. journal article 342 reference(s); 1 table(s) The reasonableness of environmental protection regulations comes under judicial review under the Administrative Procedure Act. The judicial review has generally been process oriented, giving the advantage to environmental regulations that can be rationally defended, without regard to the reasonableness of the regulation from a risk, cost, and benefit standpoint. When judicial review is conducted under the principle of more good than harm, the results may be quite different. Cases involving the ban on asbestos, risks from occupational benzene exposure, and other regulated activities are cited. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Regulating Municipal Solid Waste Incinerators Under the Clean Air Act: History, Technology and Risks Reitze, Arnold W., Jr. (George Washington University, Washington, DC); Davis, Andrew N. (Brown Rudnick Freed & Gesmer, Hartford, CT) Boston Coll Environ Aff Law Rev Fall 93 3qr v21, n1, p1 (88) Language: English Full text available from Congressional Information Service. journal article 609 reference(s) With shrinking landfill capacity and stricter regulatory requirements for municipal solid waste (MSW) disposal, incineration is being viewed as an attractive option. The hierarchy of MSW options-source reduction, recycling, landfill disposal, and incineration-is reviewed, and the history of MSW incineration and regulation are chronicled. With the advances in the technology of air pollution controls applicable to MSW incinerators, especially in the use of dry scrubbers followed by fabric filters, health risks may be at or below the risks associated with other MSW management options, even recycling. The two main weaknesses associated with incineration are the potential health risk of dioxin/furan emissions and the unproven ability of regulators to effectively control emissions over the life of an incineration 139 RISK MANAGEMENT ------- facility. It is argued that much of the public opposition to MSW incineration becomes irrational if monitoring and enforcement processes are improved. Excerpts are appended from two EPA draft documents on the environmental and health effects of dioxin release. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Salvaging Superfund; ABA developing policy on environmental cleanup law McMillion, Rhonda ABA Journal 80 93(1) Jan, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. RISK MANAGEMENT 140 ------- CHEMICAL SPECIFIC RISK MANAGEMENT (ARSENIC) Arsenic Health Research Needs Fowle, John R., Ill EPA, Research Triangle Park, NC; Abernathy, Charles 0.; Mass, Marc J.; McKinney, James D.; North, D. Warner; Ohanian, Edward V.; Uthus, Eric EPA/Univ of Missouri/et al Trace Subst in Environ Health 25th Conf, Columbia, MO May 20-23, 91 p257(15) Language: English Full text available from Congressional Information Service. conf paper 1 graph(s); 39 reference(s); 1 table(s) A near-term research agenda to resolve major risk assessment uncertainties surrounding the safety of inorganic arsenic in drinking water was prepared by an EPA ad hoc task force. Topics of interest include As toxicity and environmental exposure, uptake and metabolism, carcinogenesis, essentiality, and risk assessment/management. Research proposals focus on carcinogenic mechanisms and on the metabolism and detoxification of As. Metabolic studies are needed to determine the link between the ability to metabolize As and cancer incidence. Genetic studies are also recommended to weigh the assumption that cancer is initiated by a one-hit event followed by a second event or series of events. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (ASBESTOS) Schools respond to risk management programs for asbestos, lead in drinking water and radon. Fisher, Ann; Chestnut, Lauraine G.; Chapman, Ruth H.; Rowe, Robert D. Risk: Issues in Health & Safety 4 n4 309-328 Fall, 1993 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. 141 RISK MANAGEMENT ------- (DIISOCYANATES) Regulatory scene for selected diisocyanates Doe, J. E.; Lyon, J. P.; Katoh, M. ICI Central Toxicology Lab, Alderley Park, Engl Polyurethanes World Congress 1991 Nice, Fr, 1991 Sep 24-26 Language: English There is a multitude of governmental activities with regard to isocyanates and diisocyanates in general. For example, the U.S. Environmental Protection Agency (EPA), under the Toxic Control Substance Administration (TSCA), has both a testing requirement and a risk management process underway on the two major isocyanates, toluene diisocyanate (TDI) and methylene diisocyanate (MDI). Recently, the U.S. National Toxicology Program (1989) listed TDI as a substance which may reasonably be anticipated to be carcinogenic leading to the listing under Proposition 65 in California. Both TDI and MDI are listed by the EPA under SARA 313 requiring annual reports on emissions. In addition, there is an EPA health effects data call-up in place on 43 separate isocyanates and diisocyanates. The listing of TDI by the International! Agency for Research on Cancer (IARC) as a 2(b) carcinogen and the incorporation of both TDI and MDI in the 'Seveso' list has taken place. These activities are a result of concerns regarding: 1) toxicological data published over the last few years, 2) increased public and governmental chemical awareness and phobias, and 3) finally, in pant due to the Bhopal catastrophe involving methyl isocyanate. Activities to put perspective on the chemical class, particularly with regard to TDI and MDI, will be discussed. (Author abstract) 29 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (ENVIRONMENTAL TOBACCO SMOKE) SLO Smoke: the Anatomy of a Powerful Local Anti-Tobacco Law Wells, Barbara J. (San Luis Obispo County Health Agency, CA); Roberts, Richard L. J Environ Health, Apr 93, v55, n6, p9(5) Language: English Full text available from Congressional Information Service. journal article 13 reference(s) San Luis Obispo, CA, enacted the strictest antismoking ordinance in the nation in August 1990. The ordinance restricts smoking in all enclosed RISK MANAGEMENT 142 ------- areas used by the public including restaurants and bars. Passage of lhe ordinance is chronicled, and local political and business response is described. A positive push toward passage of the ordinance was EPA and Univ of California studies that linked involuntary exposure to environmental tobacco smoke with heart disease. The ordinance went into effect after a 30-d waiting period, and enforcement has been widespread. Despite the smoking ban, sales tax receipts for restaurants and hotels increased 7.6% over 1991 levels. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (GENERAL) Chemical risk management strategies for product stewardship and community partnership Armstrong, C.E. Dames and Moore, Raleigh, NC NAEP 18th Annual Conference, Raleigh, NC (USA), 24-26 May 1993 National Association of Environmental Professionals (NAEP) NAEP, PO Box 9400, Washington, DC 20016, USA; Telephone: (301) 229-7171, Abstracts, The Environmental Professional, ISSN: 0191-5398, Volume 15 Number 1 Supplement 1993; Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. (METHYL BROMTDE) Proposed Ban on Methyl Bromide Opposed by Producers, Users Zurer, Pamela S. Chem Eng News Feb 1 93 v71, n5, p23(2) Language: English journal article EPA advocates the phaseout of methyl bromide production, importation, and usage. The chemical, which is used as an agricultural fumigant, is thought to contribute to ozone depletion. Although former EPA head William Reilly proposed a ban prior to leaving office, action taken by President Clinton's OMB director has rendered the status of the ban uncertain. Still, the provisions of the 1990 Clean Air Act will probably require a ban on methyl bromide eventually. Principal opponents of a methyl bromide phaseout include Israel, which manufactures the chemical, and many developing countries, which use it to rid export crops of pests. Farmers in California and Florida, who use the compound for soil fumigation, also oppose the ban. 143 RISK MANAGEMENT ------- DIALOG(R)Fi!e 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (NITROGEN OXIDES) Atmospheric Nitrogen Oxides: a Bridesmaid Revisited Bachmann, John EPA, Research Triangle Park, NC Comparative Environ Risk Assessment (Lewis) 1993 p143(11) Language: English Full text available from Congressional Information Service. book chapter 2 graph(s); 1 map(s); 27 reference(s) According to risk assessments employed by EPA, air pollution has been ranked one of the top priority environmental problems. Nitrogen oxides, however, have been accorded low-risk status in most air pollution programs. Scientific evidence now indicates that atmospheric nitrogen compounds are directly responsible for respiratory problems and indirectly involved in all of the major air pollution problems. Their contribution to changes in tropospheric ozone, paniculate matter, air toxics, marine eutrophication, terrestrial systems, acidification, and stratospheric 03 depletion are reviewed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. (PCB'S) Compliance with EPA PCB regulations-Options analysis Kump, Roland K. General Electric Co, Schenectady, NY, USA IEEE Transactions on Industry Applications v 27 n 6 Nov-Dec 1991 p1162-1168 Language: English The author examines the rules, written by the Environmental Protection Agency (EPA), for regulating the use of polychlorinated biphenyls (PCBs) since the passage of the Toxic Substances Control Act by Congress in 1976. The media and state and local environmental influences have continued to highlight PCB problems. These factors, plus the aging industrial plants that contain PCBs, pose a complex problem for owners of PCB-containing equipment. The EPA rules have become more restrictive and will continue to reflect the EPA's concern with any release of PCBs into the environment. The author explores the EPA PCB regulations, highlighting the more significant requirements. The most viable options for managing PCB equipment are reviewed, and a method of RISK MANAGEMENT 144 ------- cost analysis of two of the most popular options is presented. 12 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (PCB'S) PCB regulations and procedures for risk management including PCB cleanup policy and procedures Kelly, Joseph J.; Stebbins, Randy D. 44th Annual Conference of Electrical Engineering Problems in the Rubber and Plastics Industries, Akron, OH, USA, 1992 Apr 13-14 Language: English To regulate the continued use and disposal of PCBs (polychlorinated biphenyls), the United States Environmental Protection Agency (US EPA) promulgated and is charged with enforcing the regulations contained in Title 40 Code of Federal Regulations part 761 (40 CFR 761). There is considerable confusion in industry regarding which spills and leaks are covered, how the USEPA mandates that spills and contamination be cleaned, and how PCB equipment and materials need to be disposed of. The author reviews the PCB spill cleanup policy and then discusses methods for disposal available to owners. Some methods of legal disposal, allowed under the regulations, do not eliminate risks, but may actually increase them. An alternative that eliminates the long term exposure risks caused by disposal of PCB-containing equipment is proposed. In particular, a three-step solution to this problem is put forth that depends on: specifying an appropriate method of disposal to completely destroy PCBs; utilizing vendors who are EPA approved and inspected; and reviewing thoroughly the control mechanisms and procedures used by vendors to prevent environmental exposures to PCBs and to ensure that the customers' long term liabilities are completely eliminated. 9 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (PCB'S) Why should the cement industry do anything with their PCB transformers? Kump, Roland K. GE Installation & Service Engineering, USA Proceedings of the 35th IEEE Cement Industry Technical Conference, Toronto, Ont Language: English The EPA regulations force owners of PCB equipment to carefully review regulatory compliance and develop PCB risk management programs. State 145 RISK MANAGEMENT ------- and local environmental concerns and media attention bring added , uncertainty. The many business cycles which have seen expansion and contraction of production facilities, new technology and added emission control equipment have placed added burdens on aging electrical equipment. The EPA is currently planning new PCB regulations which may add additional PCB management requirements. This paper briefly reviews the EPA regulations highlighting the more commonly violated requirements. Several risk management techniques are presented and discussed. A method of quantifying PCB equipment owning cost is presented. (Author abstract) 8 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. (PETROLEUM) Decision support system: Software for exposure/risk assessment at petroleum hydrocarbon contaminated sites Hockman, B. Amoco Corp., OK, USA 3rd Annual Symposium on Groundwater & Soil Remediation, Quebec City, PQ (Canada), 8-10 Sep 1993 BIOQUAL Network; Biotechnology Research Institute, National Research Council Canada; DESRT Program; Environment Canada; Members of GASReP/PRESSC; Ministere de I'Environnement du Quebec; St. Lawrence Centre - Environment Canada L. Gendron, Environment Canada Village Place Cartier, 3rd Fl., 425 St. Joseph Blvd., Hull, PQ K1A OH3, Canada; Telephone: (819) 953-9368; Fax: (819) 953-7253, Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK MANAGEMENT 146 ------- HAZARDOUS WASTE Cleaning Up ARARs: Reflections from the Field Temkin, Elizabeth H. Ballard Spahr Andrews & Ingersoll, Denver, CO Am Bar Assoc Environ Law Manual 1992 p98(8) Language: English book chapter A principal issue in remediating Superfund sites is the applicable or relevant and appropriate standards (ARARs). EPA and the Dep of Justice response to the issue is to extract a commitment from the potentially responsible party (PRP) to immediately install the maximum possible amount of technology to demonstrate the government's commitment to remediation. The technology-driven attitude stems from concessions from environmentalists and from the recognition that the money due from PRPs must be extracted as soon as possible. The practical impact of the government's position is examined by looking at two Superfund sites. It is argued that most of the exorbitant cash settlements do not consider realistic land uses of the site, and that the federal government generally ignores analytical data on actual impacts of the contamination. More attention must be given to site-specific data if the enormous waste incurred during remediation efforts is to be reduced. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Criteria to Be Developed to Certify WIPP Disposal Standards Compliance, EPA Says Environ Report-BNA Feb 19 93 v23, n43, p2717{38) Language: English Full text available from Congressional Information Service. journal article EPA intends to develop criteria for the management of spent nuclear fuel, high-level radioactive waste, and transuranic waste. Under the Waste Isolation Pilot Plant (WIPP) Land Withdrawal Act, EPA must certify whether the WIPP near Carlsbad, NM, complies with disposal standards. EPA is seeking comments on the propriety of confidence measures used to determine compliance. Full text of the EPA proposal is presented. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 147 RISK MANAGEMENT ------- EPA bans hazwaste burning; could set stage for related action Anon. INFECT. WASTES NEWS VOL. 8, NO. 11 1993 Language: ENGLISH U.S. Environmental Protection Agency (EPA) Administrator Carol Browner has announced that the agency will be holding up all new permits for hazardous waste incinerators, a move that could be a precursor to a second look at incineration in all waste areas, including medical waste. The decision, prompted by a long-standing dispute over startup of a new commercial hazwaste burner in East Liverpool, Ohio, changes the nation's overall outlook on burning wastes, Browner said. The action followed by one day the arrests near the White House of 50 opponents of the East Liverpool plant, including actor Martin Sheen. The agency will review all permits and run full risk assessments, including those for indirect exposure, in all new permits "to ensure they are based on the best scientific evidence." In addition, permits will be required to include an appropriate dioxin emission standard, and a "more stringent control for metals." EPA is also calling on hazwaste generators to review and overhaul how they commit themselves to reducing waste output. The nation's hazardous wastes are burned on site in 184 incinerators and 171 industrial furnaces. DIALOG(R)File 41 rPollution Abs (c) 1994 Cambridge Scientific Abstracts. All its. reserv. Hazardous Materials Transportation in Tank Cars: Analysis of Risks, Part 1 Raj PK, Turner CK Technology and Management Systems, Inc., Burlington, MA. Govt Reports Announcements & Index (GRA&I), Issue 22, 1993 NTIS/PB93-223477, 232p NTIS Prices: PC A11/MF A03 REPT-1991-64, Contract DTFR53-90-00003 Federal Railroad Administration, Washington, DC. The report covers the development of a methodology to evaluate the potential national public risk arising from the transportation of hazardous materials in tank cars on the US Railroads. The analysis is intended to assess the relative changes in the overall risk when (structural) safety devices are provided on tank cars. Also the relative risks of transporting different chemicals in a specified DOT class tank car can also be determined. An analysis of tank car accident data (maintained by the Railway Progress Institute and the Association of American Railroads) was made and statistics on tank car puncture sizes were developed. The risk model developed takes into account the characteristics of tank cars, the puncture probability, RISK MANAGEMENT 148 ------- properties of the hazardous material released and its behavior in the..environment, occurrence of the accident in different population density areas under different types of weather conditions at the time of the accident, etc. Toxicity, fire and explosion behavior of the chemicals have been considered. The focus of application of the model has been to the transporation of poison-by-inhalation (PIH) and flammable materials. The results of the risk assessment model have been presented as a matrix of frequency and consequence classes indicated by MIL standard 882 B. Final rept. Sponsored by Federal Railroad Administration, Washington, DC. TOXLINE Impacts of the use of institutional controls on risk assessments for U.S. Department of Energy facilities White, Robin K.; Redfearn, Andy; Shaw, Renee; King, Amy D. Oak Ridge Natl Lab, Oak Ridge, TN, USA Journal of Hazardous Materials v 35 n 3 Dec 1993. p 403-412 Language: English This paper summarizes some of the major issues related to the use of institutional controls at hazardous waste sites under the auspices of the U.S. Department of Energy Field Office, Oak Ridge/Environmental Restoration Division (DOE-OR/ERD). In particular, the impacts that assumptions regarding institutional controls have on the results and interpretation of the risk assessment, both in the Remedial Investigation (Rl) and the Feasibility Study (FS) are addressed. The approaches and assumptions relating to institutional controls focus on the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), since it is the regulatory driver for hazardous waste sites at Department of Energy (DOE) facilities. In order to provide a contrast to approaches adopted under CERCLA, the Resource Conservation and Recovery Act (RCRA) and radiation regulatory authorities (i.e., Nuclear Regulatory Commission (NRC) regulations/guidance, DOE orders, and U.S. Environmental Protection Agency (EPA) standards) are briefly outlined. To demonstrate the implications of the use of institutional controls at DOE facilities, the approaches and results of a recent baseline risk assessment for Solid Waste Storage Area 6 at Oak Ridge National Laboratory (ORNL) are summarized. (Author abstract) 9 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. 149 RISK MANAGEMENT ------- Managing risk at Hanford Hesser WA, Stillwell WG, Rutherford WA Battelle Pacific Northwest Labs., Richland, WA. Govt Reports Announcements & Index (GRA&I), Issue 16, 1994 NTIS/DE94008059, 8p NTIS Prices: PC A02/MF A01 PNL-SA-23727, CONF-940225-58, Contract AC06-76RL01830 Department of Energy, Washington, DC. Clearly, there is sufficient motivation from Washington for the Hanford community to pay particular attention to the risks associated with the substantial volumes of radiological, hazardous, and mixed waste at Hanford. But there is also another reason for emphasizing risk: Hanford leaders have come to realize that their decisions must consider risk and risk reduction if those decisions are to be technically sound, financially affordable, and publicly acceptable. The 560-square miles of desert land is worth only a few thousand dollars an acre (if that) - hardly enough to justify the almost two billion dollars that will be spent at Hanford this year. The benefit of cleaning up the Hanford Site is not the land but the reduction of potential risk to the public and the environment for future generations. If risk reduction is our ultimate goal, decisions about priority of effort and resource allocation must consider those risks, now and in the future. The purpose of this paper is to describe how Hanford is addressing the issues of risk assessment, risk management, and risk-based decision making and to share some of our experiences in these areas. Waste management '94, Tucson, AZ (United States), 27 Feb - 3 Mar 1994. Sponsored by Department of Energy, Washington, DC. TOXLINE * Recycled Used Oil Not Hazardous, EPA Says: Standards Issued to Govern Safe Management Environ Report-BNA Aug 14 92 v23, n16, p1187(2) Language: English Full text available from Congressional Information Service. journal article EPA has determined in a final ruling that used oil will not be regulated as a hazardous waste, since the used oil standards are adequate to protect public and environmental health. The used oil management standards cover maintenance, labeling, and storage issues. Processors, collectors, and transporters must obtain an EPA identification number, maintain storage tanks in good condition, and follow strict record-keeping procedures. Oil cannot be stored for more than 35 d and cannot be used as a dust suppressant on roads. The EPA rule has provoked a negative response from environmentalists, the RISK MANAGEMENT 150 ------- Hazardous Waste Treatment Council, and the Assoc of Petroleum . Re-Refiners. Their concerns are discussed. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Recycling Sewage Sludge: What are the Risks? Health Environ Dig Jan 93 v6, n9, p1(4) Language: English Full text available from Congressional Information Service. journal article 9 reference(s); 1 table(s) Sludge, the end product of wastewater treatment, is made up of sewage solids, organic nutrients, water, and various contaminants, including bacteria and other pathogens, industrial chemicals such as PCBs and dioxins, and heavy metals. With the recent fear of expanding landfills and the unpopularity of incineration, alternatives to sludge disposal, namely composting and application to agricultural lands, has generated widespread concern because of the potential for contaminants to be entered into the food chain or for sludge-treated soil to be ingested directly by people. These concerns and recent tests done by scientists studying sludge have prompted the EPA to enforce new sludge standards and limits of pathogens and heavy metals in sewage sludge applied to land. With the introduction of industrial discharged contaminants into sewage systems, finding new industrial processes that further reduce the occurrence of heavy metals in the environment should be a priority. In addition to effective pretreatment and careful management, safe sludge use requires continued research to provide assurance that today's regulations are protective of human health. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Regulations and techniques for dredging and dredged material disposal evaluation Rubinstein, N.I. EPA, Environ. Res. Lab., Narragansett, Rl 02882, USA WHITE PAP. SER. R.I. SEA GRANT 6 pp 1992 Based on a R.I. Sea Grant Coastal Issues in New England Lecture. Language: ENGLISH The Environmental Research Laboratory at Narragansett, R.I., is the Environmental Protection Agency's (EPA) center for marine, coastal, and estuarine water quality research. A major ongoing program at the 151 RISK MANAGEMENT ------- laboratory focuses on the development of ecological risk assessment procedures to evaluate the potential impact of contaminated sediments on the marine environment. EPA, along with the U.S. Army Corps of Engineers (COE), has responsibility for evaluating and regulating dredging and dredged material disposal operations throughout the nation. Because, in some cases, dredged materials may be contaminated with anthropogenic pollutants, it is essential that these materials be evaluated to insure compliance with environmental regulations designed to protect our marine and coastal habitats. D!ALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Risk characterisation and management of sewage sludge on agricultural land—implications for the environment and the food-chain Ross AD, Lawrie RA, Keneally JP, Whatmuff MS NSW Agriculture, Elizabeth Macarthur Agricultural Institute, Camden. REVIEW ARTICLE: 45 REFS. Aust Vet J 1992 Aug;69(8):177-81 The disposal of sewage wastes may cause severe environmental problems as was graphically demonstrated with pollution on Sydney's ocean beaches in recent years. Sewage sludges contain valuable plant nutrients and organic matter which can improve the fertility and structure of the soil. However, human parasites, pathogenic micro-organisms and chemicals capable of causing soil contamination, phytotoxicity and residues in animal products may also be present. Although sewage sludge is frequently spread on agricultural land overseas, it is not common in Australia and most states do not have specific regulations to minimise risk and promote good practice. A sludge-to-land program began in the Sydney region in 1990. It follows guidelines written by NSW Agriculture to encourage beneficial agricultural use of sludge by adoption of environmentally sustainable practices. This article describes the major risks to the food-chain and the environment, which may be associated with applying sewage sludge to agricultural land. It summarises how the risks are managed, and where further research data are required. MEDLINE Risk management considerations for controlling acid mine drainage Cobb, W.E.; Mavis, J.D. CH2M Hill 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK MANAGEMENT 152 ------- Sludge Standards Set Numerical Limits Bryant, Chris Tech Group Inc, Washington, DC Pollut Eng Jul 93 v25, n12, p48(3) Language: English Full text available from Congressional Information Service. journal article 2 photo(s); 4 table(s) EPA issued rules in early 1993 on the protection of human health and the environment from hazards posed by the disposal and reuse of sewage sludge. The ruling, referred to as the 503 rule, applies to land disposal, surface impoundments, and incineration. For each disposal option, EPA had to consider the risk to public health and the environment from the pollutants in the sludge. The 503 rule, which includes specific numerical limits, or equations for calculating the limits, for ten sewage-sludge pollutants, applies only to sewage sludge generated or treated by publicly owned treatment works. The pollutants include arsenic, cadmium, chromium, copper, lead, mercury molybdenum, nickel, selenium, and zinc. EPA has estimated that the costs of compliance could be as high as an additional $45.9 million/yr. DIALOG(R)File 40:Enviroline{R) (c) 1994 CIS, Inc. All its. reserv. Summary of the bioremediation risk assessment workshop in Minnesota in June 1993: Canadian Government guidelines on the use of microorganisms for bioremediation Mclntyre, T. Environ. Canada, ON, Canada 3rd Annual Symposium on Groundwater & Soil Remediation, Quebec City, PQ (Canada), 8-10 Sep 1993 BIOQUAL Network; Biotechnology Research Institute, National Research Council Canada; DESRT Program; Environment Canada; Members of GASReP/PRESSC; Ministere de I'Environnement du Quebec; St. Lawrence Centre - Environment Canada L. Gendron, Environment CanadaVillage Place Carrier, 3rd Fl., 425 St. Joseph Blvd., Hull, PQ K1A OH3, Canada; Telephone: (819) 953-9368; Fax: (819) 953-7253, Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 153 RISK MANAGEMENT ------- Temporary Capacity Freeze Announced by EPA on New Hazardous Waste Incinerators Environ Report-BNA May 21 93 v24, n3, p131(21) Language: English Full text available from Congressional Information Service. journal article EPA has announced an 18-month temporary capacity freeze on hazardous-waste incinerators and industrial furnaces. Incinerator operators will be required to meet new emissions standards for metals and dioxins, and prepare risk assessments. Most industrial boilers and furnaces that do not burn commercial wastes will be allowed to continue operation while complying with the new rules. A major part of the new EPA effort will be to formalize industrial-waste reduction requirements that are currently voluntary. Waste minimization will include source reduction and environmentally sound recycling, but the transfer of hazardous constituents from one medium to another will not be allowed. The new regulations will affect only incinerators operating under interim status and fully permitted operations when they come up for periodic review. Texts of the draft strategy and interim final guidance measures are provided. DIALOG{R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Use of risk to resolve conflicts in assessing hazards at mixed-waste sites Rechard, R.P.; Chu, M.S.Y. Sandia Natl. Lab., Albuquerque, NM, USA 44 pp 1991 NTIS Order No.: DE910173/GAR. SAND-91-0587C, CONF-910849-3. Language: ENGLISH This paper is primarily concerned with the scientific method of assessing hazards from mixed waste (i.e., carcinogenic chemicals, noncarcinogenic chemicals, and radioactive material). This paper discusses SRS, a Site Ranking System, and its use of risk concepts to avoid introducing new inconsistencies when ranking mixed-waste sites. SRS ranks each site by scoring factors that influence the human health risk. The factors are (1} the potentially exposed population, (2) the average amount of exposure to the waste, and (3) the toxicity of the waste. The relative risk of a release is measured as the product of these three factors. The third factor, toxicity, is indexed with a single score, but because methods of measuring toxicity differ for RISK MANAGEMENT 154 ------- carcinogenic chemicals, noncarcinogenic chemicals, and radionuclides, comparison can be difficult; hence, this paper also summarizes the logic and assumptions used to make toxicity comparisons in SRS. As may be expected, results from a ranking scheme based on risk are different from results generated by the original Hazard Ranking System (MRS), used by the Environmental Protection Agency. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. 155 RISK MANAGEMENT ------- ECONOMIC ANALYSIS Economic Benefits of Final Effluent Limitations Guidelines and Standards for the Offshore Oil and Gas Industry Anon RCG/Hagler, Bailly and Co., Inc., Boulder, CO. Govt Reports Announcements & Index (GRA&I), Issue 13, 1993 NTIS/PB93-168797, 169p NTIS Prices: PC A08/MF A02 Contract EPA-68-C8-0084 Environmental Protection Agency, Washington, DC. Office of the Assistant Administrator for Water. The report provides an overview of the benefits analysis of the effluent limitation guidelines for offshore oil and gas facilities. Regulatory options were evaluated for two wastestreams: (1) drilling fluids (muds) and cuttings; and (2) produced water. The analysis focuses on the human health-related benefits of the regulatory options considered. These health risk reduction benefits are associated with reduced human exposure to various carcinogenic and noncarcinogenic contaminants, including lead, by way of consumption of shrimp and recreationally caught finfish from the Gulf of Mexico. Most of the health-risk reduction benefits analysis is based upon a previous report (RCG/Hagler, Bailly, January 1991), developed in support of the proposed rulemaking. Recreational, commercial, and nonuse benefits have not been estimated for these regulations, due to data limitations and the difficulty of estimating these values for effluent controls in the open-water marine environment. Final rept. See also PB93-153989. Sponsored by Environmental Protection Agency, Washington, DC. Office of the Assistant Administrator for Water. TOXLINE How important is environmental risk assessment to your bottom line? Ward, C.M. Jubanyik, Varbalow, Tedesco, Shaw and Shaffer HazMat/lnternational '93: 11th Annual Presentation, Atlantic City, IMJ (USA), 9-11 Jun 1993 HAZMAT WORLD; Department of Commerce, International Trade Administration; State of New Jersey Advanstar Exposition, 800 Roosevelt Rd., Build. E, Suite 408, Glen Ellyn, IL 60137-5835, USA; Telephone: (708) 469-3373; Fax: (708) 469-7477 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK MANAGEMENT 156 ------- CORPORATE RISK MANAGEMENT ADR: A new tool for environmental managers McGlennon, J.A.S.; Schneider, P. ERM-New England Inc., Boston, MA, USA POLLUT. ENG VOL. 25, NO. 13 pp. 40-41 1993 Language: ENGLISH Alternative dispute resolution (ADR) uses neutral third parties to defuse adversarial relationships and reach cooperative solutions to environmental problems. ADR is not a new concept, it has been used for more than 15 years by several federal agencies, particularly the U.S. Environmental Protection Agency (EPA), to develop federal policy and regulations and resolve conflicts among competing interests. Several state governments have funded offices to provide ADR services to state agencies. Many groups, both profit and non-profit, around the country provide ADR services to both public- and private-sector consumers. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Beyond compliance: How an environmental risk assessment can limit a facility's liability Piatkowski, S. Consulting Services Environmental Site Assessments: Case Studies and Strategies, Orlando, FL (USA), 5-7 Aug 1992 Association of Ground Water Scientists and Engineers, National Ground Water Association (NGWA) Environmental Site Assessments, NGWA, P.O. Box 182039/Dep. 017, Columbus, OH 43218-2039, USA; Telephone: (614) 761-1711, Proceedings Paper No. A312 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Cement Makers' Long, Sweet Ride Carpenter, Betsy; Bowermaster, David US News World Report, Jul 19 93, v115, n3, p51(3) Language: English news article 1 diagram(s); 2 photo(s) The cement industry burns a million tons of solvents, hazardous wastes, 157 RISK MANAGEMENT ------- and sludge from petroleum refineries at 20 incinerator sites around the country. The industry benefits from lower fuel costs and high disposal fees charged to the generators of the waste. Although the incineration process is regulated by EPA, compliance is spotty and poorly enforced. The environmental and health consequences of incineration are not well known, but respiratory and neurological problems have been connected with exposure to incinerator discharges. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Environmental liability risk management for environmental professionals Gulledge, W.P. Tillinghast 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-FA-169.01 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. OSHA's interest in chemical plant safety Seymour, Thomas H. Safety Standards Programs Occupational Safety and Health Administration, Washington, DC, USA Plant/Operations Progress v 11 n 3 Jul 1992 p 164-165 Language: English The Occupational Safety and Health Administration (OSHA) has been required by the Clean Air Act Amendments of 1990 to promulgate a process safety management (PSM) standard for the prevention of catastrophic incidents and to protect the safety and health of employees in the covered plants. The law requires the OSHA standard to cover at least 14 areas or issues and to cover highly hazardous chemicals which include toxic, flammable, highly reactive and explosive substances. The paper will describe in detail how OSHA has responded to this statute and what we have accomplished in the rulemaking effort. Also the interface with other relevant OSHA standards, including the Hazard Communication standard, the Hazardous Waste Operations and Emergency Response standard, the Control of Hazardous Energy Sources (Lockout/Tagout) standard, and others will be discussed. In addition other recent laws that relate to and impact the OSHA PSM standard such as the Hazardous Materials Transportation Uniform Safety Act of 1990, RISK MANAGEMENT 158 ------- the Oil Pollution Act of 1990, and the Superfund Amendments and, Reauthorization Act (SARA) of 1986, will be explained as to their relationship to PSM. The emergency preparedness efforts required of employers under PSM and the relationship to SARA Title III efforts by local community emergency response organizations will be covered, as well as the interface with the EPA Risk Management Program initiative that EPA must do under the Clean Air Act Amendments. (Author abstract) 4 Refs. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. Responsible care and distribution risk management Roco, E.W. Industrial Safety, Roco BVBA, Belgium MARICHEM '93, Amsterdam, The Netherlands, 30 Nov - 2 Dec 1993 British Marine Equipment Association Gastech RAI Ltd.200-208 Tottenham Court Rd., London W1P9LA, UK, full papers Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Source Resolution and Risk Apportionment to Augment the Bubble Policy: Application to a Steel Plant "Bubble" Mukerjee, Shaibal; Biswas, Pratim Univ of Cincinnati, OH Environ Manag Springer-Verlag Jul-Aug 93 v17, n4, p531(13) Language: English Full text available from Congressional Information Service. research article 47 reference(s); 11 table(s) A specific aspect of the EPA Emission Trading Policy is known as the Bubble Policy, which allows state regulatory agencies to limit air-pollution emissions in an industrial source complex from a total emissions perspective rather than a point-by-point reduction throughout the plant. Conceptually, the complex is enclosed in an imaginary bubble with a single stack opening at its top. The company can decrease or increase emissions in a cost-effective manner as long as total emissions do not exceed ambient standards. Mathematic models are presented to identify emission-source categories and to quantitatively apportion the risk contribution estimates affecting a receptor site in the airshed. Risk apportionment rests on the fundamemtals of receptor modeling that identifies and determines the contribution of an element 159 RISK MANAGEMENT ------- pollutant. The modeling scheme was applied to a steel plant in Ohio to determine participate matter in the airshed and risk-reduction options for the plant. Results indicated that open dust sources were primary emission sources in the plant, and increasing spray efficiency on open dust sources could reduce overall inhalation risks. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Toxics Management in the Chemical and Petrochemical Industries Englande, Jr. A. J. (Tulane Univ, New Orleans, LA); Guarino, C. F. (WRC Inc, Huntingdon Valley, PA) Water Sci Technol 1992 v26, n1-2, p263(12) Language: English research article The status of hazardous waste management and treatment in the chemical and petrochemical sectors is profiled. Regulatory /legal considerations and trends are surveyed, and the EPA approach to wastewater discharge regulation is critiqued. Advances in analytical/biological methods for toxicity characterization are noted. Successful company programs that promote waste minimization, source reduction, process modifications, reuse, and recycling are cited. Other topics covered were innovative techniques for effluent treatment and sludge/oily waste handling. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. Whose risk is it anyway? Pinkowski, Brian Smuggler Mine Project, Aspen, CO, USA Civil Engineering (New York) v 63 n 10 Oct 1993. p 66-68 Language: English Near the now-closed Smuggler Mine in Aspen, Colo., toxic lead sits beneath the grass of area residents' yards. A major portion of soil in the area contains lead above the EPA action level of 1,000 parts per million soil lead for the sit. For the last nine years, EPA and residents of Aspen, Colo, have been locked in a battle over how best to handle mine wastes left over from the city's silver mining past. Here, the EPA project manager takes a look at the compelling arguments on both sides of the issue. DIALOG(R)File 8:Ei Compendex*Plus(TM) (c) 1994 Engineering Info. Inc. All rts. reserv. RISK MANAGEMENT 160 ------- RISK COMMUNICATION THE PROCESS OF EDUCATING AND INFORMING AN AUDIENCE TO MAKE BETTER PERSONAL ANS SOCIETAL DECISIONS REGARDING RISK ------- This page intentionally left blank. ------- INFORMING THE DECISION-MAKER Corporate risk communication: New challenges for makers and users of toxic chemicals Baram, M. Cent. Law and Technol., Boston Univ. Law Sen., Boston, MA, USA POLLUT. PREV. REV VOL. 3, NO. 2 pp. 167-175 1993 Language: ENGLISH Since the mid-1980s, right-to-know policies have stimulated voluntary efforts by many companies to prevent pollution and improve plant safety. Another effect of these laws is that facility managers have become increasingly involved in risk communication in order to gain public trust. Improvements in risk communication are needed, however, and companies must now prepare for the new communication challenges posed by the Clean Air Act Amendments of 1990. DIALOG(R)File 41 Pollution Abs (c) 1994 Cambridge Scientific Abstracts. All rts. reserv. Effect of Bright Lines in Environmental Risk Communication Wilson, (Catherine N. Research Triangle Inst, Research Triangle Park, NC; Desvousges, William H.; Smith, Kerry V.; Payne, John Natl Assoc of Environ Professionals 19th Annual Conf Proc, Raleigh, NC May 24-26 93 p451(14) Language: English Full text available from Congressional Information Service. conf paper 1 diagram(s); 15 reference(s); 4 table(s) The term "bright lines" is used in environmental risk documents to denote the levels at which a given environmental hazard poses a severe threat to health requiring action. Radon occurrences are usually classified as bright lines. The bright line value for Rn is the concentration at which an individual's risk of developing lung cancer is increased. Currently, exposures to more than 4 pCi/l of Rn are considered dangerous. The value of bright line-based terminology in risk communications is assessed. DIALOG{R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 163 RISK COMMUNICATION ------- Information quality evaluation and applications to health risk assessment Wassom, J.S.; Ross, R.H.; Lu, P.Y. 203rd American Chemical Society National Meeting and Exposition, San Francisco, CA (USA), 5-10 Apr 1992 ACS, Distribution, Room 210, 1155 16th Street NW, Washington, DC 20036, USA; Telephone: 800 227-5558, select 2, Abstracts; $40.00 non-members, $30.00 ACS member, $28.00 ACS member and member of an ACS division Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. M&A and the EPA Heiderscheit, III, John W.; Belden, Roy S. Chadbourne & Parke. DC Indep Energy Feb 94 v24, n2, p27(3) Language: English Full text available from Congressional Information Service. journal article Environmental issues are as important in evaluating a merger or acquisition in the independent power market as in evaluating a new project. Since contamination liability os a major concern when considering the purchase of an existing project, a bring-down study should be initiated to assess the potential for hazardous waste contamination at a site. The study will also review all permits and determine which are still lacking. The timetable for issuance of new permits or updating environmental restrictions requires review DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All its. reserv. Risk communication: The Convergence model of communication as a conceptual foundation for environmental risk communication Bradbury, J. Battelle/Pacific Northwest Laboratories, Washington, DC, USA Fourteenth Annual Meeting of the American College of Toxicology, New Orleans, LA (USA), 3-6 Oct 1993 ACT9650 Rockville Pike, Bethesda, MD 20814, USA; Telephone: (301) 530-0033, Abstracts Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. RISK COMMUNICATION 164 ------- Role for risk communication in closing military waste sites Klauenberg BJ, Vermulen EK Radiofrequency Radiation Division, Armstrong Laboratory, Brooks Air Force Base, Texas 78235-5114. Risk Anal; VOL 14, ISS 3, 1994, P351-6 JOURNAL ARTICLE Language: English Lessons learned from environmental and occupational hazard risk management practices over the past 30 years have led the Department of Defense to explore alternative risk management approaches. Policies for cleanup of environmentally hazardous waste sites are undergoing examination and are being reframed. A Demonstration Risk Communication Program is described which incorporates principles that integrate risk-based scientific information as well as community values, perceptions, and needs in a democratic process that includes the public as an active participant from the earliest stages. A strong scientific foundation for assessment and characterization of risk is viewed as necessary but not sufficient; the public's values must be actively integrated into the negotiated criteria. The Demonstration Program uses a model to prepare the participants and to guide them through the process. A five-step process is presented: (1) create risk communications process action team including at least one member of the specific site audience; (2) professionally train participants on team dynamics including interpersonal communication skills; (3) train risk communicators to deliver a cogent presentation of the message to secure a decision acceptable to both the government and the public; (4) identify existing biases, perceptions, and values held by all participants; and (5) develop risk message incorporating science and values. The process action team approach assumes the participants enter into the effort with the goal of improved environment and safeguarded public health. The team approach avoids confrontational or adversarial interactions and focuses on a dialogue from which a negotiated team response develops. Central to the program is the recognition that communication is only effective when the dialog is two-way. TOXLINE USAF/EPA team approach to CERCLA cleanup and risk communication Null, M.K.; Christian, D. U.S. EPA Reg. VIM Federal Environmental Restoration '92, Vienna, VA (USA), 15-17 Apr 1992 Hazardous Materials Control Research Institute HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA. Fax: (301) 220-3870. Telephone: (301) 982-9500., Proceedings Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. 165 RISK COMMUNICATION ------- INFORMING THE PUBLIC Case study of health risk communication: what the public wants and what it gets Trauth, Jeannette M. Risk: Health, Safety & Environment 5 n1 49-64 Wntr, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All its. reserv. Notification guidelines for risk communication under the air toxics "HotSpots" program Kaiser, S.; Alexeeff, G.V. California Air Resour. Board 86th Air & Waste Management Association Annual Meeting and Exhibition, Denver, CO (USA), 13-18 Jun 1993 A&WMA, PO Box 2861, Pittsburgh, PA 15230, USA; Telephone: (412) 232-3444; Fax: (412) 232-3450, Proceedings Paper No. 93-TP-36B.04 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. Public involvement and risk communication for Rocky Flats health studies Zoda, S.; Lockhart, A. ENSR Consult, and Eng. 1993 Federal Environmental Restoration Conference and Exhibition, Washington, DC (USA), 25-27 May 1993 Hazardous Materials Control Resources Institute (HMCRI); Dep. Energy; Dep. Def.; Army Corps Eng.; Dep. Navy; EPA; Bur. Reclarri.; Air Force; Nav. Facil. Eng. Command; Dep. Inter.; Agency Toxic Subst. and Dis. Regist. HMCRI, 7237 Hanover Parkway, Greenbelt, MD 20770-3602, USA; Telephone: (301) 982-9500; Fax: (301) 220-3870, Proceedings, HMCRI member: $58.50 and non-member: §65.00 Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All its. reserv. RISK COMMUNICATION 166 ------- The question of risk: incorporating community perceptions into environmental risk assessments (Urban Environmental Justice) Freeman, James S.; Godsil, Rachel D. Fordham Urban Law Journal 21 n3 547-576 Spring, 1994 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. Risk communication to the media and general public: A case study of a dioxin contaminated site Nessel, C.S. Exxon Biomed. Sci. HazMat/lnternational '93: 11th Annual Presentation, Atlantic City, NJ (USA), 9-11 Jun 1993 HAZMAT WORLD; Department of Commerce, International Trade Administration; State of New Jersey Advanstar Exposition, 800 Roosevelt Rd., Build. E, Suite 408, Glen Ellyn, IL 60137-5835, USA; Telephone: (708) 469-3373; Fax: (708) 469-7477, Proceedings, $105.00 plus $10.00 shipping charge Language: English DIALOG(R)File 77:Conference Papers Index (c) 1994 Cambridge Sci Abs. All rts. reserv. Testing the role of technical information in public risk perception Johnson, Branden B.; Sandman, Peter M.; Miller, Paul Risk: Issues in Health & Safety 3 n4 341-364 Fall, 1992 LRI File 150 DIALOG(R)File 150:Legal Resource Index(TM) (c) 1994 Information Access Co. All rts. reserv. 167 RISK COMMUNICATION ------- INFORMING THE WORKER Biases in perception and reporting following a perceived toxic exposure Lees-Haley PR, Brown RS REVIEW ARTICLE: 60 REFS. Percept Mot Skills 1992 Oct;75(2):531-44 Reactions to chemical exposures often include fears of future illness,, cancerphobia, reports of multiple chemical sensitivity, and other ill-defined complaints. Frequently, these complaints occur at levels of exposure not known to cause physiological harm. Although frequently dismissed as hysterical or hypochondriacal reactions, these complaints, along with other indefinite symptoms, may be better understood in terms of biases in perception and reporting. In this paper, we outline various sources of perceptual and response biases including prior beliefs, the media, influential others, reconstructed personal histories, self-perceptions, and the forensic environment. It is recommended that a thorough understanding of symptom-reporting and psychological distress following a chemical exposure involves consideration of these issues. MEDLINE RISK COMMUNICATION 168 ------- BIBLIOGRAPHIES AND OTHER SOURCES ------- ASTER: An Integration of the ACQUIRE Data Base and the QSAR .. System for Use in Ecological Risk Assessments Russom CL, Anderson EB, Greenwood BE, Pilli A Environmental Research Lab.-Duluth, MM. Computer Sciences Corp., Duluth, MN. Govt Reports Announcements & Index (GRA&I), Issue 19, 1992 NTIS/PB92-198217, 6p NTIS Prices: PC A02/MF A01 EPA/600/A-92/141 Ecological risk assessments are used by the US Environmental Protection Agency (US EPA) and other governmental agencies to assist in determining the probability and magnitude of deleterious effects of hazardous chemicals on plants and animals. These assessments are important steps in formulating regulatory decisions. The completion of an ecological risk assessment requires the gathering of ecotoxicological hazard and environmental exposure information. The information is evaluated in the risk characterization section to assist in making the final risk assessment. ASTER (Assessment Tools for the Evaluation of Risk) was designed by the US EPA Environmental Research Laboratory-Duluth (ERL-D) to assist regulators in producing assessments. ASTER is an integration of the AQUIRE (AQUatic toxicity Information REtrieval system) and QSAR (Quantitative Structure Activity Relationships) systems. AQUIRE is a data base of aquatic toxicity tests and QSAR is comprised of a data base of measured physicochemical properties, and various QSAR models that estimate physicochemical and ecotoxicological endpoints. ASTER will be available to international governmental agencies through the US EPA National Computing Center. (Copyright (c) 1991 Elsevier Science Publishers B.V.) Journal article. Pub. in The Science of the Total Environment 109/110, p667-670 1991. See also PB88-130034 and PB91-137083. Prepared in cooperation with Computer Sciences Corp., Duluth, MN. TOXLINE Glossary for Ecotoxicology and Risk Assessment NTIS/AD-A258 543/8 Mayer KS Naval Aerospace Medical Research Lab., Pensacola, FL. Govt Reports Announcements & Index (GRA&I), Issue 08, 1993 NTIS/AD-A258 543/8, 20p NTIS Prices: PC A03/MF A01 Rept no. NAMRL-SR92-2 As in other scientific disciplines, environmental toxicology has a standard vocabulary to convey information about the effects of contaminants on the 170 BIBLIOGRAPHIES/OTHER SOURCES ------- environment. These words are highly technical and are not usually defined in readily available sources such as standard dictionaries. Consequently, the vocabulary of environmental contamination can be ambiguous and confusing. A Glossary for Ecotoxicology and Risk Assessment was prepared to help alleviate this problem. It contains over 200 terms relating to environmental contamination. Some terms, such as 'tolerance', are used in other disciplines, but they have specific meanings when they are associated with the field of environmental contamination. Words that are adequately defined in other readily available sources have not been included in the Glossary. Selection of terms for the Glossary followed an extensive literature review. Criteria for selection included frequency of use, and availability and accuracy of published definition. Final definitions were synthesized from those in the literature and other glossaries, and by consulting experts in the fields of environmental toxicology and chemistry. The Glossary is intended for use by the Navy in addressing environmental issues should they occur. It is written in semitechnical language for those who lack formal training in environmental toxicology, but who require a working knowledge of the subject. Many of the definitions include examples or explanations containing background information. Final rept. TOXLINE A Practitioner's Guide to the Toxic Substances Control Act: Part III Hathaway, Carolyne R. Latham & Watkins, Washington, DC; Hayes, David J., Rawson, William K. Environ Law Report Jul 94 v24, n7, p10357(23) Language: English Full text available from Congressional Information Service. journal article 264 reference(s) The provisions of sections 6 and 7 of TSCA, which cover regulation of existing chemicals and imminently hazardous substances, are explained. The reporting and recordkeeping requirements of section 8 are examined, as are import certification and export notification mandates of sections 13 and 12{b). Civil and criminal enforcement under sections 15 and 16 are also reviewed. Topics covered include regulation of PCBs and asbestos, disclosure of health and safety studies, civil penalty policies, and notice of substantial risks. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 171 BIBLIOGRAPHIES/OTHER SOURCES ------- Public Health Assessment Guidance Manual, March 1992 NTIS/PB92-147164 Anon Agency for Toxic Substances and Disease Registry, Atlanta, GA. Govt Reports Announcements & Index (GRA&I), Issue 16, 1992 NTIS/PB92-147164, 303p NTIS Prices: PC A14/MF A03 The Agency for Toxic Substances and Disease Registry's highest priority is the protection of public health. The authors address that priority through actions that mitigate or prevent adverse health effects and diminished quality of life resulting from exposures to hazardous substances in the environment. Because large numbers of hazardous waste sites and facilities can potentially affect public health, ATSDR must have an instrument of triage to determine where, and for whom, public health actions should be undertaken. The Agency's instrument of choice is the public health assessment, which characterizes the nature and extent of hazards and identifies communities where public health actions are needed. The Public Health Assessment Guidance Manual provides the environmental health professional with directions for implementing that important public health tool. See also PB91-214858. TOXLINE U.S. EPA Geographic Information System for Mapping Environmental Releases of Toxic Chemical Release Inventory (TRI) Chemicals Stockwell, John R. EPA, Atlanta, GA; Sorensen, Jerome W. et al. Risk Anal 1993 v13, n2, p155(10) Language: English research article 1 drawing(s); 5 map(s); 8 reference(s); 1 table(s) Human health and environmental effects data from the EPA Office of Pollution Prevention & Toxics were computerized in a format compatible with the EPA geographic information system (GIS) in order to produce risk-assessment maps of the southeastern US. Chemical data from the 1987 Toxics Release Inventory (TRI) were used in the study. By utilizing EPA GIS and the TRI database, it may be possible to identify and manage previously undetected potential exposure zones before they materialize as areas with an excess of actual environmental diseases and injuries. As illustration of the monitoring program, maps are provided of emission areas at risk for carcinogens, developmental and reproductive toxins, and agents capable of producing heritable mutations. DIALOG(R)File 40:Enviroline(R) (c) 1994 CIS, Inc. All rts. reserv. 172 BIBLIOGRAPHIES/OTHER SOURCES ------- TITLE INDEX ------- This page intentionally left blank. ------- Absolutely green: if asbestos is banned because it's hazardous, what's next? Fire? . . 67 Acceptable risk: a conceptual proposal 3 Accident prevention and the Clean Air Act Amendments of 1990 with particular reference to anhydrous hydrogen fluoride 64 Acute and Genetic Toxicity of Municipal Landfill Leachate 54 Adapting ecological risk assessment for ecosystem valuation 104 ADR: A new tool for environmental managers 158 Advances in risk assessment and management 120 Air quality modeling and its role in the risk assessment at Valdez, Alaska 84 Alar: the EPA's Mismanagement of an Agricultural Chemical 64 Analyses of natural resources in 10 CFR part 60 as related to inadvertent human intrusion 24 Appropriate role of risk assessment in risk analysis 14 Army Material Command environmental risk management program 126 Arsenic Health Research Needs 142 Arsenic Risk Assessment 65 Arsenic: Risk assessment for California drinking water standards 66 Assessing Ecological Hazard Under TSCA: Methods and Evaluation Data 104 Assessing health risks associated with DDT residues in soils in California: A Proposition 65 case study 68 Assessing pesticide exposure for relative risk assessment 58 Assessing risk-toxicity in perspective 3 Assessment and communication of risks from pesticide residues in food 45 Assessment and evaluation of genotoxicity findings 53 Assessment of Genetically Engineered Microorganisms Under TSCA: Considerations Prior to Use in Fermentors or Small-Scale Release 105 Assessment of health risk from wastes in three surface impoundments 84 175 TITLE INDEX ------- ASTER: An Integration of the ACQUIRE Data Base and the QSAR System for Use in Ecological Risk Assessments 172 Atmospheric Nitrogen Oxides: a Bridesmaid Revisited • 145 The benefits of probabilistic exposure assessment: three case studies involving contaminated air, water, and soil . 86 Benzene Mixtures Raise Health Questions . 67 Beyond compliance: How an environmental risk assessment can limit a facility's liability 158 Biases in perception and reporting following a perceived toxic exposure 170 Bottomland Hardwoods in the Tifton-Vadalia Upland of Georgia: A Conceptual Model for Ecological Risk Assessment 106 Building our nation's CIS treasure chest: The environmental risk assessment process as a catalyst to growth 3 Carcinogen risk assessment 51 Carcinogenic and reproductive risk assessment under the California Proposition 65 statute 55 A case study of health risk communication: what the public wants and what it gets 168 Case study: Human health and ecological baseline risk assessment of wastewater reuse for Seattle Metro .<• 58 The Cement Makers' Long, Sweet Ride 157 The Challenge of ecological risk assessment 106 Chemical accident prevention under the Clean Air Act Amendments of 1990 73 Chemical and radiological risk factors associated with waste from energy production 85 Chemical risk management strategies for product stewardship and community partnership ... 144 Chemical stabilization of dewatered sludge, a pilot study and health risk assessment of use as landfill closure/repair material 86 Chemicals versus microbials in drinking water. A decision sciences perspective 86 CHEMRISK, a multiple-exposure pathway risk assessment model 45 Cleaner Water, But Not Clean Enough 4 TITLE INDEX 176 ------- Cleaning Up ARARs: Reflections from the Field ., 148 Climate Research for Ecological Monitoring and Assessment: a New England Example 107 Comparative Assessment of Estimated vs. Actual Emissions and Associated Health Risks from a Modern Municipal Waste Combustor 87 Comparison of Predicted and Observed Dioxin Levels in Fish: Implications for Risk Assessment 70 Comparison of radiological risk assessment methods for environmental restoration 45 Comparison of risks from outdoor and indoor exposure to toxic chemicals 88 A Comparison of the Integrated Uptake Biokinetic Model to Traditional Risk Assessment Approaches for Environmental Lead 75 Compliance with EPA PCB regulations-Options analysis 145 Conceptual structure of performance assessments conducted for the waste isolation pilot plant 45 Construction of complementary cumulative distribution functions for comparison with the EPA release limits for radioactive waste disposal 87 Coping with the risk of cancer in children living near power lines 46 Corporate risk communication: New challenges for makers and users of toxic chemicals 164 Criteria to Be DeveHped to Certify WIPP Disposal Standards Compliance, EPA Says 148 A Critique of risk modeling and risk assessment of municipal landfills based on U.S. Environmental Protection Agency techniques 89 Decision support system: Software for exposure/risk assessment at petroleum hydrocarbon contaminated sites 147 Degradation of polychlorinated dibenzo-p-dioxin and dibenzofuran contaminants in 2,4,5,-T by photoassisted ironcatalyzed hydrogen peroxide 71 Dermal penetration of 14C-labeled diisopropyl methylphosphonate in swine 69 Determining target cleanup levels. A risk assessment-based decision process for contaminated sites 89 Development of a specific-locus assay in the ad-3 region of two-component heterokaryons of Neurospora: a review 55 The Development of SAR/QSAR for Use Under EPA's Toxic Substances Control Act (TSCA): an Introduction 27 177 TITLE INDEX ------- Developmental and reproductive toxicology: Ensuring the quality of data used for.. risk assessment 4 Developmental effects of endocrine-disrupting chemicals in wildlife and humans 55 Dioxins/furans: U.S. EPA ecological risk assessment for land application and disposal methods for paper pulp sludge 72 Distinctions and lessons learned from CERCLA: Using site-specific risk assessment to control remediation costs in the RCRA facility investigation 58 Dow Scientist Issues Strong Defense of New Method of Calculating Worker Risk/ EPA Backs Pharmacokinetic Approach in Estimating Risk for Exposed Workers 46 DRASTIC Mapping to Determine the Vulnerability of Ground Water to Pollution . 27 Drilling intrusion probabilities for use in performance assessment for radioactive waste disposal 90 Earthquake Hazard Associated with Deep Well Injection a Report to the U.S. Environmental Protection Agency 91 Ecological Hazard Evaluation and Risk Assessment Under EPA's Toxic Substances Control Act (TSCA): an Introduction 108 Ecological Investigation of a Hazardous Waste Site, Warner Robins, Georgia 92 Ecological risk assessment framework - the NAS perspective 108 Ecological risk assessment in NPDES permits: Quantitative methods for the calculation of expected risk 109 Ecological risk assessment of a metals-contaminated wetland: Reducing uncertainty 109 Ecological risk assessment procedures and applications to the CERCLA process 110 Ecological risk assessment: a scientific perspective 111 Ecological risk management: Cost of attaining acceptable risk 111 Ecological Risk Assessment Report, Submerged Quench Incinerator, Task IRA-2, Basin F Liquids Treatment Design. Version 3.0 111 Economic Benefits of Final Effluent Limitations Guidelines and Standards for the Offshore Oil and Gas Industry 157 The Effect of Bright Lines in Environmental Risk Communication 164 Emissions from the incineration of nerve agent rockets containing low-level PCBs 79 TITLE INDEX 178 ------- Environmental concerns prompt Section's activity. (Section of Natural Resources,. Energy and Environmental Law) (ABA/NYC) 139 Environmental Decision Models: U.S. Experience and a New Approach to Pollution Management 28 Environmental Equity and the Environmental Professional 5 Environmental genotoxicity and cancer risk in humans: a combined evaluation correlating the results of the Tradescantia micronucleus assay in the field and human biomarker assessments in serum. I. The TRAD-MCN assay 56 Environmental health risk assessment: Regulatory approach to assessing public health risks of a toxic chemical spill in the Sacramento River 24 Environmental liability risk management for environmental professionals Environmental Monitoring and Assessment Program Assessment Framework 14 Environmental risk assessment for determining the priorities 59 An Environmental risk assessment questionnaire 28 Environmental risk assessment 5 Environmental risk assessment: the divergent methodologies of economists, lawyers and scientists 5 Environmental risk factors of cancer and their primary prevention 51 Environmental Risk Assessment of New Chemicals Under the Toxic Substances Control Act (TSCA) Section Five 14 EPA Airs Shift Toward Pollution Prevention 15 EPA bans hazwaste burning; could set stage for related action 149 EPA Continues Probe on Dangers of Showering, Labels Passive Smoking a Carcinogen 16 EPA Lists Toxic Chemicals to Help Protect Public from Accidental Releases 16 EPA Looks at Superfund Reform 126 EPA Plans More Flexible Guidelines to Assess Cancer Risk from Chemicals 17 EPA priorities for biologic markers research in environmental health 127 EPA Proposes Chemical Risk Management Rule to Prevent, Prepare for Accidental Releases ... 16 EPA Publishes List of Substances, Thresholds Subject to Chemical Accident Prevention Rules 5 179 TITLE INDEX ------- EPA Study Points to Health Risks of Dioxins and Similar Compounds , 73 EPA to reaffirm hazards to health posed by dioxin 71 EPA toxic substances program: Long-standing information planning problems must be addressed 127 EPA's approach to environmental research in the 90s 18 EPA's research to improve health risk assessments (RIHRA) program Overview and water-related research 6 Escarpment seeps at Shiprock, New Mexico 112 Establishing Generic Remediation Goals for the Polycyclic Aromatic Hydrocarbons: Critical Issues 82 Estimating Risk at a Superfund Site Contaminated with Radiological and Chemical Wastes .... 92 Evaluating the risk of liver cancer in humans exposed to trichloroethylene using physiological models 83 Experimentalist's look at risk assessment 7 Exposure and risk assessment of chemicals in food and drinking water 59 Exposure/risk-based corrective action approach for petroleum-contaminated sites 81 Fear and loathing in the siting of hazardous and radioactive waste facilities: a comprehensive approach to a misperceived crisis 92 Federal Appeals Court Upholds Regulations, Finds Agency Properly Set Contaminant Levels ... 139 Formation and control of brominated ozone by-products 47 A Framework for Ecological Risk Assessment at the EPA 112 From rats to regulations; environmental risk assessment based on the health effects of substances on rodents is widespread, costly, and unreliable. (World in Peril: Responding to Expanding Environmental Enforcement) 28 Future directions and research needs 120 Glossary for Ecotoxicology and Risk Assessment Guidance for data useability in risk assessment 18 Harmonizing chemical and radiation risk management 120 The Hawaii Environmental Risk Ranking Study 29 TITLE INDEX 180 ------- Hazardous Materials Transportation in Tank Cars: Analysis of Risks, Part 1 ... 149 Health Advisories for Pesticides 59 Health and chemical environment in Czecho-Slovakia, international cooperation context 128 Health Hazard Evaluation Report HETA 92 Health risk assessments: a critical scientific technique for environmental regulators and litigators 7 Health risks associated with residential exposure to extremely low frequency electromagnetic radiation 60 Health Studies Indicate MTBE Is Safe Gasoline Additive 78 Hemoglobin adducts of N-substituted aryl compounds in exposure control and risk assessment 66 Historical accident data and chemical emergency risk management 121 Historical re-evaluation of a risk assessment 7 How "safe" is the ground water Americans drink? 19 How important is environmental risk assessment to your bottom line? 157 How to design an ecological risk assessment 113 How to Move Quickly to Risk-Based Environmental Management: a Specific Proposal 128 Identification of Tire Leachate Toxicants and a Risk Assessment of Water Quality Effects Using Tire Reefs in Canals 93 The Impact of Data Gaps in EPA's Regional Comparative Risk Projects 7 Impact of EPA regulatory and policy initiatives on risk management and waste disposal strategies for the mining industry 129 Impacts of the use of institutional controls on risk assessments for U.S. Department of Energy facilities 150 In the village square: risk misperception and decisionmaking in the regulation of low-level radioactive waste 94 Inadequacy of commonly used risk assessment guidance for determining whether solvent-contaminated soils can affect groundwater at arid sites 29 Incineration, Risk Assessment, and the Clean Air Act 94 Incorporating risk assessment into the senior process design course 8 181 TITLE INDEX ------- The Increasing Importance of Risk in Environmental Decision-Making 121 Indoor air: Potential health risks related to residential wood smoke, as determined under the assumptions of the US EPA risk assessment model 30 Information quality evaluation and applications to health risk assessment 165 Inhalation risk assessment for all power plants in Maryland 47 Interim Report on Data and Methods for Assessment of 2,3,7,8-Tetrachlorodibenzo-p- dioxin Risks to Aquatic Life and Associated Wildlife 72 An inter- and intra-agency survey of the use of plants for toxicity assessment 30 Interlaboratory comparison of the early life-stage toxicity test using sheepshead minnows (Cyprinodon variegatus) 31 The International toxicity equivalency factor (I-TEF) method for estimating risks associated with exposures to complex mixtures of dioxins and related compounds 32 Interpretation of male rat renal tubule tumors 19 Introduction: Methods for environmental quantitative risk assessment 33 Investigation of a spontaneous abortion cluster: lessons learned 57 Lawn Care Pesticides: Reregistration Falls Further Behind and Exposure Effects Are Uncertain 94 Legislating acceptable cancer risk from exposure to toxic chemicals 48 Lender liability and environmental risk management 138 The Lessons of Commencement Bay. A pioneering study in Puget Sound helped advance ecological risk assessment 113 M&A and the EPA 165 The magnitude of compounding conservatisms in Superfund risk assessments 24 Managing environmental compliance - balancing the risks 122 Managing risk at Hanford 151 Marine ecological risk assessment at Naval Construction Battalion Center, Davisville, Rhode Island. Phase 1 114 Maximum Dosage Level in Testing Low-Toxicity Chemicals for Carcinogenicity in Rodents 48 TITLE INDEX 182 ------- A Method for Assessing Environmental Risk: a Case Study of Green Bay, Lake Michigan, USA 33 A Method for Obtaining Guidance for the Combination of Qualitative Rankings by Cancer and Noncancer Risks into a Single, Qualitative Health Risk Ranking 48 Methodology for aquatic ecological risk assessment 115 Multimedia transport, fate, exposure and risk assessment: Strategies developing evaluative, integrative computer software 34 Mutagenicity test schemes and guidelines: U.S. EPA Office of Pollution Prevention and Toxics and Office of Pesticide Programs 20 National survey of drinking water standards and guidelines for chemical contaminants 123 The New Air Toxics Program 123 New approaches in setting drinking water standards 130 New focus on air toxics 124 Non-Hodgkin's lymphoma and occupation in Sweden: a registry based analysis 52 Non-Occupational Exposures to Pesticides for Residents of Two U.S. Cities 95 Not by risk alone: reforming EPA research priorities 8 Notification guidelines for risk communication under the air toxics "HotSpots" program 168 « NPS and NEPA: An analysis of the legal impact of the UN principles relevant to the use of nuclear power sources in outer space on the current practice of environmental risk assessment under domestics 25 Odor thresholds in relation to risk assessment 34 OSHA Nearing Completion of Options Paper for New Administration 130 OSHA's interest in chemical plant safety 159 OSHA's interest in risk management and accident prevention 131 OSWER Environmental Justice Task Force Draft Final Report Executive Summary 8 PCB regulations and procedures for risk management including PCB cleanup policy and procedures 168 Performance evaluation of sperm cell toxicity test using the sea urchin, Arbacia punctulata 34 Permitting and compliance programs for toxic discharges 131 183 TITLE INDEX ------- Pesticide Use Trends and Issues in the United States ,. 9 PHA case study using HAZOP and selective application of quantitative risk assessment 35 A Practitioner's Guide to the Toxic Substances Control Act: Part III 173 Predicting risk by looking at the past; health dangers for exposed workers and the public can be assessed by reconstructing a facility's processes and products. (World in Peril: Responding to Expanding Environmental Enforcement) 35 Prediction of Vulnerable Zones for Reactive Substances 36 Preliminary air quality risk assessment for a groundwater treatment facility 96 Presentation of a general algorithm to include effect assessment on secondary poisoning in the derivation of environmental quality criteria. Part 1. Aquatic food chains 36 Prioritizing ecological and human welfare risks from environmental stresses 20 Proceedings of the American Chemical Society 204th National Meeting on the Role of Environmental (Ecological) Assessment in the Management of Chemical Pollution . 131 Progress report on EPA's 33/50 Program: Reducing toxic risks through voluntary action 132 Proposed Ban on Methyl Bromide Opposed by Producers, Users 144 Public Health Assessment Guidance Manual, March 1992 174 Public involvement and risk communication for Rocky Flats health studies 168 Qualitative and quantitative issues in assessment of neurotoxic effects 49 A quality process for chemical product risk assessment 21 The question of risk: incorporating community perceptions into environmental risk assessments 169 The Quotient Method of Ecological Risk Assessment and Modeling Under TSCA: a Review ... 115 Radium concentration factors and their use in health and environmental risk assessment 82 RCRA at a Crossroads: Whether to Regulate Hazardous Waste Based on Risk or Technological Controls 132 Re-Evaluation of the Reference Dose for Methylmercury and Assessment of Current Exposure Levels 78 Reassessing the scope of federal biotechnology oversight 21 Recognizing the limits of risk assessment 9 TITLE INDEX 184 ------- Recycled Used Oil Not Hazardous, EPA Says: Standards Issued to Govern Safe Management . . 151 Recycling Sewage Sludge: What are the Risks? 152 Reducing risk: Priorities and strategies for environmental protection 133 Regulating Municipal Solid Waste Incinerators Under the Clean Air Act: History, Technology and Risks 140 Regulating the introduction of new chemicals under section 5 of TSCA: improving the efficiency of the process and reducing potential injury in the workplace through the use of operational MSDS and exposure limits 133 Regulation of Environmental Contaminants in Drinking Water: State Methods and Problems ... 134 Regulation of existing chemicals under TSCA: information disclosure as the route to reducing risk and increasing available data 134 Regulations and techniques for dredging and dredged material disposal evaluation 152 Regulatory and institutional considerations in the application of ecological risk assessment at federal facilities 135 Regulatory Problems Associated with Natural Products and Biopesticides 135 Regulatory scene for selected diisocyanates 143 Research to improve health risk assessments: Setting the stage for residual risk assessment of the hazardous air pollutants 49 Responsible care and distribution risk management 160 Review of Ecological Effects and Bioconcentration Testing Recommended by the TSCA Interagency Testing Committee and Implemented by EPA Under the Toxic Substances Control Act: Chemicals, Tests, and Methods 37 Revising the Risk Assessment Paradigm: Limits on the Quantitative Ranking of Environmental Problems 21 Risk and the New Rules of Decisionmaking: the Need for a Single Risk Target 25 Risk assessment and air quality at Superfund sites 96 Risk assessment and closure of former underground storage tanks site in southern California 96 Risk assessment and management of chemical contaminants in fishery products consumed in the USA 60 Risk assessment and risk management of noncriteria pollutants 136 185 TITLE INDEX ------- Risk assessment at a Super-fund site: A case study 97 Risk assessment based on current release standards for radioactive surface contamination ... 22 Risk assessment for a proposed regional hazardous waste management facility 97 Risk assessment framework of fate and transport models applied to hazardous waste sites ... 98 Risk assessment in the Environmental Protection Agency (EPA) 10 Risk assessment methodology: The California experience 38 Risk assessment methods for establishing clean closure levels 38 Risk Assessment/Management Issues in the Environmental Planning of Mines . 61 Risk Assessment, Metals Emissions and the Clean Air Act Amendments of 1990 75 Risk Assessment of Dibromochloropropane 69 Risk assessment: good for health? 10 Risk-Based Evaluation of Ground-Water Contamination by Agricultural Pesticides 62 Risk characterisation and management of sewage sludge on agricultural land- implications for the environment and the food-chain 153 Risk characterization framework for noncancer end points 52 Risk communication to the media and general public: A case study of a dioxin contaminated site 169 Risk communication: The Convergence model of communication as a conceptual foundation for environmental risk communication 165 Risk Evaluation of Lead in Soil and Groundwater at the H. Brown Superfund Site in Walker, Michigan 76 Risk management considerations for controlling acid mine drainage 153 Risk of Benzene-Induced Leukemia: a Sensitivity Analysis of the Pliofilm Cohort with Additional Follow-Up and New Exposure Estimates 67 Risk of congenital malformations associated with proximity to hazardous waste sites 98 Risk Variability from Uniform Soil Remediation Goals for PCBs 79 The risks of fixing the current federal system of risk assessment 137 Role for risk communication in closing military waste sites 166 TITLE INDEX 186 ------- Role of chemically induced cell proliferation in carcinogenesis and its use in health risk assessment 137 The Role of Comparative Risk Analysis 10 The role of property-reactivity relationships in meeting the EPA's needs for environmental fate constants 38 Role of quantitative risk assessment in chemical releases and wastewater treatment plant design 74 Safety/Risk Assessment of Chemicals: Principles, Procedures, and Examples 74 Salvaging Superfund; ABA developing policy on environmental cleanup law 142 Scheduled risk assessment application for the DoE programs 99 Schools respond to risk management programs for asbestos, lead in drinking water and radon 142 Science and judgment in risk assessment 11 Scientists Urge Senate Panel to Consider Non-Cancer Health Effects of Contamination 63 Selection of Indicator Chemicals at Hazardous Waste Sites 99 Senators show support for measure requiring environmental risk assessment 26 Simplified approach to environmental risk assessment at superfund sites 22 <• SLO Smoke: the Anatomy of a Powerful Local Anti-Tobacco Law 143 Sludge Standards Set Numerical Limits '. 154 Source Resolution and Risk Apportionment to Augment the Bubble Policy: Application to a Steel Plant "Bubble" 160 Stop Superfund Waste 124 Strategic analysis study-based approach to integrated risk assessment: Occupational health risks from environmental restoration and waste management activities at Hanford 100 Strategies for contracting for quality risk assessment data 23 Structure/Activity Relationships for Evaluation of Biodegradability in the EPA's Office of Pollution Prevention and Toxics 39 Summary of the bioremediation risk assessment workshop in Minnesota in June 1993: Canadian Government guidelines on the use of microorganisms for bioremediation 154 187 TITLE INDEX ------- Superfund and one community program 100 Temporal Variations in Exposure Data 39 Temporary Capacity Freeze Announced by EPA on New Hazardous Waste Incinerators 155 Terrestrial wildlife exposed to agrochemicals. An ecological risk assessment perspective 116 Testing the role of technical information in public risk perception Total exposure assessment in occupational epidemiology for risk management 125 Toxic VOC emissions from a POTW in southern California and associated health risk assessment for a permit to operate 83 Toxicity assessment of hazardous waste at a Federal facility 101 Toxicity equivalency factors for PCBs 80 Toxicological basis for drinking water: Unreasonable risk to health values 50 Toxicology and risk assessment 12 Toxicology of upper aerodigestive tract pollutants 101 Toxics Management in the Chemical and Petrochemical Industries 161 Transaction screening is a useful risk management tool, (part 1) 137 Transferring federal property using qualitative risk assessment 40 The TSCA Interagency Testing Committee, 1977 to 1992: Creation, Structure, Functions and Contributions 12 The TSCA Interagency Testing Committee's Role in Facilitating Development of Test Methods: Toxicity and Bioconcentration Testing of Chemicals Added to Sediments 40 TSCA: the Sleeping Giant Is Stirring 12 The U.S. EPA Geographic Information System for Mapping Environmental Releases of Toxic Chemical Release Inventory (TRI) Chemicals 173 Union Officials Question Reasoning for Risk Level of OSHA Health Standards 102 USAF/EPA team approach to CERCLA cleanup and risk communication 166 The Use and Application of QSARs in the Office of Toxic Substances for Ecological Hazard Assessment of New Chemicals 116 Use of microbial risk assessment in setting US drinking water standards 41 TITLE INDEX 188 ------- The Use of Quantitative Structure-Activity Relationships (QSARs) as Screening Tgols in Environmental Assessment 41 Use of risk to resolve conflicts in assessing hazards at mixed-waste sites 155 Using an uncertainty analysis of direct and indirect exposure to contaminated groundwater to evaluate EPA's MCLs and health-based cleanup goals 42 Using Ecological Risk Assessment Methods 43 Using the RESRAD computer code to evaluate human health risks from radionuclides and hazardous chemicals 103 The Utility of Environmental Fate Models to Regulatory Programs 137 Utilization of Uptake Biokinetic (UBK) Lead Model to Assess Risk in Contaminated Sites 77 Valdez air health study proven approach to community risk assessment of air toxics emissions 64 Validation of some extrapolation methods used for effect assessment 23 Validation of Structure Activity Relationships Used by the USEPA's Office of Pollution Prevention and Toxics for the Environmental Hazard Assessment of Industrial Chemicals 43 Value Assumptions in Risk Assessment: A Case Study of the Alachlor Controversy 44 Wastes: Toxic Substances Control Act 137 When Is a Life Too Costly to Save? The Evidence from Environmental Regulations 138 White House Postpones Risk Assessment Reform 13 Whose risk is it anyway? 161 Why should the cement industry do anything with their PCB transformers? 146 189 TITLE INDEX ------- |