United States
                  Environmental Protection
                  Agency
Environmental
Research Laboratory
Athens GA 30613-7799
                                                                       N*

                                                                      •*!>"•
                  Research and Development
EPA/600/S3-88/048 June 1989
&EPA         Project Summary

                  Effects  of Temperature and
                  Redox Conditions  on
                  Degradation of  Chlorinated
                  Phenols  in Freshwater
                  Sediments
                 John E. Rogers, Gert-Wieland Kohring, and Juergen Wiegel
                   The physical and chemical proper-
                 ties of the sediment environment can
                 vary in  time as well as in  location.
                 Sediment temperatures change over
                 the seasons, and  sediments directly
                 exposed to the sun in summer can
                 reach temperatures  in excess of
                 50°C. Freshwater sediments are
                 primarily  methanogenic,  whereas
                 marine  sediments are dominated by
                 sulfate  reducing conditions. These
                 fluctuations and  differences can
                 influence  chemical  as  well  as
                 microbiological processes  involved
                 in the transformation or degradation
                 of hazardous organic chemicals.
                 Therefore, during the development of
                 mathematical models to predict the
                 fate of  toxic organic compounds in
                 the environment,  it is important to
                 include  parameters that describe the
                 influence of temperature and chem-
                 ical characteristics on anaerobic bio-
                 degradation.
                   The effect  of  temperature and
                 redox conditions  on the anaerobic
                 degradation of 2,4-dichlorophenol
                 (2,4-DCP) was  investigated  in
                 anaerobic sediment slurries prepared
                 from  local  freshwater pond
                 sediments. Under methanogenic
                 conditions, 2,4-DCP dechlorination
                 occurred in the temperature  range
                 between  5 and   50°C. Although
                 dechlorination  was  not  observed
above 50°C,  anaerobic bacterial
activity was  Indicated by methane
formation up to 60 °C. In sediment
samples from two sites and at all
temperatures from 5 to 50°C, 2,4-DCP
was transformed to  4-chlorophenol
(4-CP). The 4-CP  was further
degraded after several  weeks.
Adaptation  periods decreased
between 5 and 25 "C, were essentially
constant between 25 and 35°C, and
increased between 35 and 40 °C.
Degradation rates increased expo-
nentially between 15 and 30°C, had a
second peak at 35 °C and decreased
to about 5%  of the peak activity by
40 "C. In one sediment sample, an
increase in degradation  rates  was
observed following the minimum at
40 "C, suggesting that at least two
different organisms were involved in
the 2,4-DCP dechlorination.
  The addition of sulfate at a level of
0.25% resulted in a marked reduction
in the rate of methane formation, a
marked reduction in the  rate of
reductive  dechlorination,  and an
increase  in  the  length  of  the
adaptation period before reductive
dechlorination  could be detected.
The addition  of nitrate at a level of
0.15% resulted in  the  complete
inhibition  of the reductive
dechlorination reaction for at least
127 days.

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  Storage  of the original sediment
slurries for 2 months at 12°C resulted
in increased adaptation times, but did
not affect the degradation rates.
  This Project Summary  was  devel-
oped by  EPA's  Environmental
Research Laboratory,  Athens, GA,  to
announce key findings of the research
project that Is fully documented in a
separate report of the same title (see
Project Report ordering information at
back).


Introduction
  The full report  explains  the  effect  of
temperature and redox conditions on the
reductive dechlorination  of  2,4-dichloro-
phenol (2,4-DCP) and 4-chlorophenol (4-
CP) sediment slurries. It also shows that,
for a restricted temperature  (e.g.,from  15
to 30°C),  dechlorination  rates  under
methanogenic conditions  can  be
described by an Arrhenius function.
  Both 2,4-DCP and 4-CP are released to
the environment by direct disposal or  as
break-down   products   of  higher
chlorinated compounds such  as the
extensively used wood preservative pen-
tachlorophenol (PCP) or the herbicides
2,4-dichlorophenoxyacetic  acid  (2,4-D)
and  2,4,5-trichlorophenoxyacetic  acid
(2,4,5-T).  These compounds are highly
toxic and 4-chlorophenol is  a suspected
carcinogen. Thus, there  is a clear need
for modeling the fate of these compounds
in order to evaluate their potential risk to
man and his environment.
  The reductive dechlorination of  chloro-
phenols has been reported in a variety of
anaerobic sediments such  as sewage
sludge, sediment, and subsurface aquifer
environments, all of which were methano-
genic. Only recently has the reductive
dechlorination of 2,4-DCP been reported
to  occur  under  sulfate reducing
conditions and,  to our   knowledge,
reductive dechlorination under denitri-
fying  conditions has  not been  reported.
The proposed  pathway for the anaerobic
degradation  of 2,4-DCP   is the  pro-
gressive replacement of the chlorines  by
hydrogen (reductive dechlorination)  lead-
ing to phenol, which  is  then  further
degraded to methane and carbon dioxide.
Similar reductive  pathways  have been
reported  for chlorinated benzoates and
other chlorinated phenols.
  The addition of sulfate to methanogenic
aquifer materials  has  resulted  in  the
inhibition of the dechlorination reaction.
Interestingly,  however,  the  degradation
intermediate  phenol was  readily  de-
graded under sulfate reducing conditions.
Adding sulfate to methanogenic aquifer
material  has  also led  to  increased
degradation of cresols.  Unfortunately,
little  else is known about the effects of
environmental factors on these reactions.
An extensive study of the effects of redox
couples or temperature has  not  been
reported.  Our  work was undertaken  to
learn more of these effects to provide a
better  base for the  development  of
environmental fate and effects models.

Procedures
  Freshwater lake  sediments  from two
different sites  near Athens, GA,  were
used  in  this  investigation.  Individual
reaction flasks consisted of anaerobic
tubes that were filled with 20  ml  of
sediment slurry and crimp  sealed  with
butyl rubber stoppers. All  procedures
were conducted  under  flowing nitrogen
that  had  been purged  of oxygen.
Methanogenic slurries were prepared by
combining sediment with site water  to
give 0.2 to 0.4 mg dry wt. sediment/ml of
slurry,  adding  sufficient 1  M  K2HP04/
KH2P04 to yield a buffer concentration of
20 mM, and then adjusting the pH to 6.9
by the addition of small quantities of 2 N
NaOH.  The  slurries were prepared in a
blender and were periodically mixed to
obtain a  homogeneous solution. Sulfate
reducing or denitrifying  slurries  were
prepared  by adding sulfate (0.25%)  or
nitrate (0.15%), respectively.
  Degradation experiments were initiated
by adding 0.7 ml of an aqueous 2,4-DCP
stock  solution  to  give  a   final
concentration of  about 125  iimol/l  (20
ppm). Duplicate samples were incubated
in  waterbaths at different temperatures.
Sediment  slurries  were  removed
periodically and combined with an  equal
volume of  acetonitrile  to terminate  the
reaction  and to facilitate recovery  of
compounds  bound  to the sediment
matrix. These mixtures were subseq-
uently  analyzed  by high  performance
liquid chromatography  (HPLC) for 2,4-
DCP, 4-CP, phenol,  and  benzoate. Abiotic
controls were  prepared  by  autoclaving
the sediment samples on 3 consecutive
days for  45 min each before  2,4-DCP
was added.
  For methane formation experiments, 10
ml of the slurry without  2,4-DCP were
placed in  Hungate  tubes and the filled
tubes  were  then  incubated  in a
temperature gradient  incubator  (7  to
80°C)  with  continuous  shaking. Period-
ically, 100-jil samples  were  taken  from
the headspace with a gas lock syringe
and  the  methane  concentration  deter-
mined by gas chromatography.
Conclusions
  The  authors  observed  a sequential
dechlorination  of  2,4-DCP  in  the
temperature range  between 5 and 52 °C
for unacclimated sediment  dominated by
methanogenic  activity.   At  all
temperatures, the first product was 4-CP,
and although at least two different groups
of microorganisms  were involved in  2,4-
DCP  degradation  at the  different
temperatures, they all  used  the  same
reaction to initiate degradation.
  The authors also found  that,  although
anaerobic microbial dechlorination of  2,4-
DCP occurred from  5  to  52°C, only  a
small  portion of the  data  (15  to  35°C]
could  be fit to an Arrhenius equation
Above  and below  the  linear  range  the
temperature dependence varied  marked-
ly. Although this range appears limited, i'
does  indicate the temperatures ovei
which microorganisms  will significantly
influence the fate of chlorinated  aromatic
compounds  in anaerobic  environments
and does cover  a  significant  fraction o
environments  where  these  micro'
organisms would be active. Furthermore
it indicates  that laboratory tests could be
performed  at the faster  rates  (e.g. a
28°C) and  then extrapolated to  environ
mental temperatures (e.g. at 20 °C).
  Unlike a  chemical  reaction where
temperature may only affect the  reaction
in a microbiologically mediated  process
temperature affects both the compositioi
of the active community and the enzyme
catalyzed  reaction. The effects o
population  become even more  pro
nounced when more  than one organism
as in the case of reductive dechlorinatior
may be required for activity and differen
organisms  may  catalyze the  rate
determining step at  different tempera
tures. In this study, the major peaks c
activity observed above and below 40 °<
probably resulted from the contribution
of thermophilic  and  mesophilic orgar
isms, respectively.  Interestingly,  becaus
thermophilic activity was only observed i
half of  the  samples from one of  th
sediments,  the  key thermophilic orgar
isms appeared  to  be present at  signi
icantly lower numbers.
  Storing sediment samples before  us
appeared to affect  adaptation  more  tha
the  rate of dechlorination.  For exampli
adaptation  periods, determined  over th
temperature  range  of  5  to  25°
decreased from a range of 140 to 8 dav
for the fresh sediments  to a range of 27
to 12 days  for the sediments stored for
months  at 12°C. The corresponding  2,
DCP  transformation  rates  were  m
significantly affected. Therefore the  ui

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kof  stored  samples  could  lead  to
 srroneous  estimates  of  the  adaptation
'period.
  Under sulfate  reducing conditions, the
 rate of reductive dechlorination activity
 was observed only between 18 and 40°C
 after 365 days  incubation.  More  than
 30% of the  sulfate  remained  following
 complete degradation of the 2,4-DCP and
 methanogenic activity  was inhibited for
 the duration of the experiment. The  rates
 varied  from 2  to  19%  of  the  rates
 observed  under methanogenic condi-
 tions.  No reductive  dechlorination  was
 observed under denitrifying  conditions
 after 127 days of incubation.

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 The EPA author, John £. Rogers (also the EPA Project Officer, see below), is with
   the Environmental Research Laboratory, Athens, GA  30613-7799;  Gert-Weiland
   Kohring and Juergen Wiegel are with the University of Georgia, Athens, GA.
 The complete report, entitled "Effects of Temperature  and Redox Conditions on
   Degradation of Chlorinated Phenols in Freshwater Sediments," (Order No.  PB
   89-729 US/AS; Cost: $73.95, subject to change) will be available only from:
         National Technical Information Service
         5285 Port Royal Road
         Springfield, VA 22161
         Telephone: 703-487-4650
 The EPA Project Officer can be contacted at:
         Environmental Research Laboratory
         U.S. Environmental Protection Agency
         Athens, GA 30613-7799
United States
Environmental Protection
Agency
Center for Environmental Research
Information
Cincinnati OH 45268
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