United States
                  Environmental Protection
                  Agency
Office of Acid Deposition, Environmental
Monitoring and Quality Assurance
Washington, DC 20460
$1
                  Research and Development
EPA/600/S9-88/011  Sept. 1988
&EPA         Project  Summary
                  A  Computerized Bibliographic
                  Literature  Information  System  for
                  Total  Human  Exposure
                  Monitoring  Research

                  Michael Dellarco, Wayne Ott, Lance Wallace, and Herb Hunt
                    The  Bibliographic  Literature  In-
                 formation System (BUS)  is a com-
                 puterized data base that  provides a
                 comprehensive review of available
                 literature on total human exposure to
                 environmental pollution.  Brief ab-
                 stracts  (often condensed versions of
                 the original abstract) are included; if
                 the  original  document had  no
                 abstract, one was prepared. Unpub-
                 lished reports are listed,  as well as
                 final reports of  the  U.S.  Gov-
                 ernment and other countries, reports
                 by governmental research contrac-
                 tors, journal articles, and  other con-
                 tributions to the field of total  human
                 exposure research. This bibliography
                 covers  publications  on  exposure
                 models, new field data, and newly
                 emerging research methodologies.
                 Although the bibliography covers the
                 entire  field  of  human  exposure
                 methodology, emphasis is on those
                 field studies measuring all the
                 concentrations to which people may
                 be exposed, including indoors, out-
                 doors, or in-transit This report lists
                 the  788 full abstracts and  all
                 keywords contained in the BUS sys-
                 tem  as of  fall  of 1987. The 788
                 abstracts provide a good rep-
                 resentation  of much of  the world
                 literature on  total human exposure
                 and  indoor air  quality.  The time
                 period  covers 1962 to the end of
                 1986, with only a few abstracts from
                 early 1987.
                    Versions  of this data base are
                 available on floppy diskettes that can
 be  accessed on  IBM-compatible
 personal  computers.  Different
 versions are available that will run on
 either a floppy disk or on a hard-
 disk system. These computer pro-
 grams can search for abstracts
 rapidly and  print  out desired
 combinations of literature citations
 and full abstracts. In practice, these
 abstracts can  serve the user  as an
 "automated index"  of the BUS data
 base on total  human exposure and
 indoor air quality.
  This  Project  Summary  was
 developed by  EPA's Office of Acid
 Deposition, Environmental Monitoring
 and Quality Assurance, Washington,
 DC, to announce key findings  of the
 research project that  is fully doc-
 umented in a separate report  of the
 same  title (see  Project Report
 ordering information at back).
Introduction
  Total human exposure monitoring is a
new concept that seeks  to determine,
with known precision and accuracy, the
pollutant concentrations actually reaching
people  through  food, water,  and air,
whether people  are located  indoors,
outdoors, or in-transit. Such monitoring
provides the key information needed  to
protect  public  health and to make risk
assessments  through  representative
samples of the general population. This
new field also includes:
• Surveys of human activity patterns;

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•  Models designed to predict human
   exposures from activity;
•  Studies of the pollutant concentrations
   found  in the microenvironments that
   people  visit,  such as  in-transit
   vehicles and  indoor  and  outdoor
   settings.
   The emergence of this new topic over
the last  two  decades as a cohesive
scientific field has been accompanied by
a rapid growth in the scientific literature.
To facilitate access to  this literature, the
U.S.  Environmental  Protection Agency
(EPA)  developed the Bibliographical
Literature  Information  System (BLIS)  to
assist managers and  scientists respon-
sible for planning  total human exposure
research.  BLIS  currently consists of a
data  base of 788 abstracts  of journal
articles, reports by contractors, and other
scientific  documents  up to  February
1987.  The entire data base  can  be
transported on  5.25"  floppy diskettes,
and the BLIS program runs on an IBM-
PC/XT or  equivalent to retrieve, search,
and print out  these  abstracts efficiently.
One  version of this program,  BLIS  II,
requires only a single disk drive, while a
second can be  installed on  a hard disk
drive, requiring  about  1.3  megabytes  of
disk space.

Design Criteria
   BLIS was designed  to  meet the
following criteria:
•  Is user  friendly; no personal computer
   (PC) experience  and no written
   manual.
•  Uses  programming  in  the  public
   domain;  proprietary commercial
   programs need not be purchased.
•  Is completely portable;  uses standard
   floppy disks.
•  Changes drives to  accommodate
   different data bases  and PCs.
•  Employs  Microsoft Disk  Operating
   System (MS-DOS)  file management
   capabilities. Individual files or  groups
   of files may be  copied using DOS.
•  Can be used with  all PC clones.
•  Abstracts, files, and  keywords, entirely
   in  American  Standard  Code  for
   Information  Interchange (ASCII) text.
   (Any text editor can be used  on  the
   data base.)
•  Does not restrict size of abstract files.
•  Provides  well  written,  easy-to-
   understand abstracts of the scientific
   literature.
•  Allows printing  of reference and/or full
   abstracts.
•  Automatically lists  all  references  or
   citations alphabetically  with automatic
   generation of page numbers and  an
   index.
•  May  be  string  searched  for any
   keyword quickly, with slower full-text
   search capability available.
•  Provides high speed keyword search.
   Uses arrays where possible to achieve
   Random Access Memory (RAM) high
   speed  search (for  example,  150 +
   abstracts/second).
•  Provides alphabetical list  of authors
   and a keyword search list which can
   be called up to assist the user.

File Structure Requirements
   The file structure is  intended  to  be
compatible with virtually  every  word
processing package as well as  scores of
other programs  that can  import  ASCII
files without  control characters.  Each
citation  is contained in  a  separate  file
easily located  by  use  of the  BLIS
reference number within the file  name.

Development of the Data Base
   BLIS was designed to  accommodate
only  studies of human  exposure  to
environmental pollution. The aim was to
construct a comprehensive bibliography
consisting of  human  exposure, and
studies of sources of indoor pollutants or
exposures.
   BLIS emphasizes studies  in  which
pollutants  were  observed in contact with
members  of  the general  public  rather
than specific  occupational  groups. BLIS
includes all pollutants and  categories of
pollutants  except asbestos. Because of
the  extensive  data  bases  already
available on radon, the  literature in BLIS
on radon is not complete.
   Five  key  journals were scanned  as
sources for BLIS:
•  Environmental Research
•  Environment International
•  Environmental  Science  and
   Technology
•  Journal of the Air Pollution Control
   Association
•  Atmospheric Environment
   Other sources of  materials  were the
proceedings  of pertinent conferences
and symposia, two bibliographic reviews
on  indoor air quality, and  reports, both
published and  unpublished, from EPA
and other federal agencies.
   After  approximately 400  abstracts
were entered  into  BLIS,  a report was
prepared  listing these  abstracts. This
report was sent to many of the authors
with a letter requesting that they  review
the 400-abstract  manuscript for  its
accuracy and send additional articles and
reports that should be included. Replies
were received  from  the U.S.,  Denmark,
Germany, Japan,  the  Netherlands,
Switzerland, and Yugoslavia.  Most  re-
spondents  had  favorable  commenl
about  BLIS and nearly all  reviewei
included additional articles or citations f<
inclusion  in  BLIS. All of these article
along with  many others, were entere
into the system to give the 788 abstraa
currently comprising the data base.
   One  of  the  most  importar
considerations  in  the development  <
BLIS  was  the criteria  establishing
keyword search capability Keywords ar
relevant to indoor air and  total huma
exposure.  They are  single words; n
combinations are used. Keywords includ
cities, pollutants,  foreign  nations,  and
great variety of nouns and adjectives.
   Citations,  abstracts  and  keyword
were edited by a scientific reviewer and
professional  technical editor  to ensur
uniform quality control  and  concise
comprehensive abstracts.
   BLIS was developed in two versions
•  Floppy  Version  -  "BLIS  II"  is  fc
   users without a hard drive  It consist
   of seven  disks: a main program  dis
   and six  data base disks covering 196
   through Feb. 1987. BUS II requires
   single  5.25"  disk drive,  256K  c
   memory, and DOS 2.0 or higher. BLi:
   II is limited to accessing 999 abstract;
•  Hard Disk  Version  - "HIGHBLIS
   allows users to search the entire  dat
   base at one time. All years of data ar
   searched as  a combined  group  c
   files. This version fits on 10  diskette
   and requires about 1.3 megabytes c
   disk  space.  HIGHBLIS  must  b
   installed  on  a subdirectory callei
   "C:\HIGHBLIS"  to  be  operationa
   HIGHBLIS theoretically has the abilit
   to access up to 9,999 abstracts.
   Both versions of BLIS  present!
contain  788 abstracts. Because of  th
number of abstracts that can be pnntei
out efficiently, a laser or other high spee<
printer is very helpful.
   A report is being prepared describmi
the BLIS system and data base,  includmj
a  full listing  of  the  788 abstracts  am
literature  citations  currently  in  BLIS
Copies of this report  will  be  madi
available from  both  the Environmente
Protection  Agency  and  the  Nations
Technical Information Service.
   Currently a  mechanism  is  beim
explored  for  distributing  the  BLI!
software  and  its data base on  flopp'
diskettes.  The software  is in the pubiii
domain and is available  for a reasonabli
fee covering duplication and  handlini
charges from:

Herb Hunt
PrograManagement Systems          (
Suite 100

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 1377 K Street, NW
I Washington, DC 20005

 Using BUS
   Perhaps  the  easiest  way  to
 understand the  BUS  software functions
 is to  illustrate  a typical  use  of the
 system: With the floppy version (BLIS II),
 the user inserts the main disk into one of
 the disk drives  and  types  "BLIS II." A
 welcome  banner identifies the  system
 and  its authors and  asks  the user to
 "press  any  key to continue." The next
 screen  instructs the  user to  place the
 disk for the "years of interest" in the disk
 drive and "press any key to  continue."
 Six functions are available  on the  BLIS
 main menu  of options:  Set Up  Printer,
 Display System Author  List,  Search  for
 Specific Author, Search Abstracts  for
 Keywords, Return to  Menu,  and  Search
 Every Word in Every Abstract.
   Assuming the user  wants to perform a
 keyword search  for information coded in
 BLIS, option 4 would  be the mam menu
 option choice. The system  instructs the
 user  to  use  standard   chemical
 nomenclature  (i.e. Fe,  CO,  NOa) and
 notes that all keywords are in lower case
 except acronyms and proper names.
   Suppose  the  user  searches for the
 keyword "model" in the  1984  volume of
 BLIS. After entry of  the  word "model,"
 BLIS reports 33 matches found out of
 189 abstracts searched in the year 1984.
 The  33  BLIS  II  abstract  reference
 numbers  (3-digit codes)  appear  at the
 top  of  the  screen.   Sub-options  then
 permit  the user to search  for  a new
 keyword, display or print  the citations or
 abstracts associated with  the found
 keyword, or return to the  main menu .
   If the user specifies  option 4,  BLIS
 prints the screen displayed citation,
 keywords,  and  the  full   abstract
 alphabetically, by author.
   In  the future, the  following en-
 hancements  to BLIS   will  be  fully
 explored:
 •  Expanding  the   data   base   by
   increasing the number of abstracts.
 •  Further refining  the keywords  to
   improve search capabilities.
 •  Improving  the speed of  HIGHBLIS
   searches by using larger arrays.
 •  Making HIGHBLIS  available to  IBM
   System 2 users.
 •  Investigating  high-density storage
   media such as CD-ROMS  (Compact
   Disk  - Read  Only  Memories).
   EPA participates in  the Human
 Exposure  Assessment Location  (HEAL)
 (project, an effort sponsored  by  World
 Health Organization  (WHO) designed to
 improve the quality of human exposure
data  collected  globally.  Technology
transfer and  training  are important
components  in  the establishment  of
HEAL. Not all of  the  participants  are
actively involved  in total human exposure
monitoring  and  must familiarize them-
selves with the  theory and practice of
this emerging field.
   BLIS has  received  a favorable
reception in WHO and among several of
the participants.  In the future, it  may
serve not only as a central repository for
technical information and  past studies
concerning human exposure monitoring
but also may be appealing because it is
easily  transportable  to  foreign  col-
leagues. For  those countries  where
English is a second language, BLIS may
be especially useful  because it can be
queried to produce only those citations
which  are immediately relevant  to  the
issue  at  hand.  This  would  facilitate
retrieval of technical reports  and  min-
imize  translation costs to only those
studies deemed  necessary for  particular
HEAL studies. Currently, officials in WHO
headquarters, Geneva, are evaluating the
utility of BLIS for transferring information
to member states.

Conclusion
   BLIS currently is  built  on  the  total
human exposure and indoor air  quality
literature and can  be adapted to other
topics. BLIS  demonstrates  that today's
personal computer can be used as a
literature searching  tool to assist re-
searchers and  officials seeking infor-
mation on projects that may not  yet be
published  in the scientific literature, as
well  as papers given  at scientific
meetings and articles in journals.
   The  BLIS approach  is  especially
suited  to emerging new scientific fields,
such as total human exposure, where the
literature is not  yet too voluminous. At
the present time, the authors believe that
the 788 abstracts  in BLIS represent a
substantial  fraction of  the world's lit-
erature on human exposure  to  envi-
ronmental pollution (excluding radon and
asbestos) up to February 1987, the  date
the last abstract was entered.  In 1988,
they  plan  to add  about 300  more
abstracts to the  system. At present, no
decision has  been  made  about ex-
panding the  data base  beyond 1988. If
the data base expands, it might be useful
to explore CD-ROMS  as  the system
storage medium.
   By  following  a design  concept of
"maximum  compatibility"  with  all other
software and  word processors  that use
DOS,  the system and its data  base are
extremely flexible and easy to  use.  The
system  is ideally suited to "technology
transfer" activities that seek to educate
personnel about  rapidly emerging  fields.
In  its current form, BLIS, and the  report
developed from  it, can help promote  a
wider  understanding  of  the  many
advances that  are being  made in total
human exposure  monitoring research and
will facilitate  improved communication
among   federal, state,  and  local
governments,  universities  and private
consulting firms, and foreign countries.

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  Michael Dellarco, Wayne Ott  (also the  EPA Project  Officer),  and Lance
       Wallace,  the EPA authors,  are  with the Office  of Acid  Deposition,
       Environmental Monitoring and Quality Assurance, Washington, DC 20460.
       Herb Hunt is with PrograManagement Systems, Silver Spring, MD 20901.
  The  complete  report,  entitled "A Computerized Bibliographic Literature
       Information  System for Total Human Exposure Monitoring Research,"
       (Order No. PB  88-250 3601 AS; Cost: $38.95, subject to change) will be
       available only from:
           National Technical Information Service
           5285 Port Royal Road
           Springfield, VA22161
           Telephone:  703-487-4650
  The EPA Project Officer can be contacted at:
           Office of Acid Deposition, Environmental Monitoring and Quality
               Assurance
           U.S. Environmental Protection Agency
           Washington, DC 20460
United States
Environmental Protection
Agency
Center for Environmental Research
Information
Cincinnati OH 45268
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