United States
                     Environmental Protection
                     Agency
Health Effects Research
Laboratory
Research Triangle Park NC 27711
                    Research and Development
EPA-600/S2-83-018 Aug. 1983
ŁEPA         Project Summary

                    Radiofrequency  Radiation
                    Exposure  Facilities  for
                    Bio-Effects  Research
                    Joseph S. AM and Claude Weil
                      This report describes the multi-user
                     radiofrequency radiation exposure
                     facilities for bio-effects research in use
                     at  the  Health  Effects  Research
                     Laboratory, Research Triangle Park,
                     NC. Four facilities are described: (1) a
                     100 MHz CW exposure system, (2) a
                     2450 MHz CW exposure system, (3) a
                     2450 MHz AM exposure system, and
                     (4) an X-band  pulsed  RF exposure
                     system.  In  the  final  report,  the
                     individual  facility descriptions include
                     construction  details,  specifications,
                     photographs,  circuit drawings  and
                     block  diagrams.  All of the  facilities
                     incorporate environmental control
                     systems, and three have RF power-level
                     regulation.

                      This Project Summary was developed
                     by  EPA's Health  Effects  Research
                     Laboratory. Research Triangle Park,
                     NC, to announce key findings  of the
                     research project that is fully document-
                     ed in a separate report of the same title
                     (see Project Report ordering informa-
                     tion at back).

                     Introduction
                      One  of the  missions  of  the
                     Environmental  Protection Agency (EPA)
                     is  to  investigate  the  effects  of
                     radiofrequency radiation (RFR) exposure
                     on  biological organisms. The EPA has
                     been  involved in  this effort since its
                     creation in 1970. This report focuses on
                     the major RFR exposure facilities in use
                     by  the  Health  Effects  Research
                     Laboratory at the Research Triangle Park,
                     N.C.
                      The operating  frequency   of  an
                     exposure system determines to a large
                     degree the types  of exposure systems
that  can  be employed.  For example,
transverse electromagnetic  mode
transmission  lines  (TEM  cells)  are
generally not useful above approximately
1 GHz because of the small size required
to prevent the propagation of unwanted
higher order modes. Likewise, anechoic
chambers  become  impractical and
expensive below about 400 MHz because
of the large size of the anechoic material
and the chamber itself. Selection of the
operating  frequency generally  results
from one of two motives: (1) a facility is
designed  to simulate  some  environ-
mentally occurring exposure situation
over  some narrow portion  of  the RF
spectrum, or (2) an exposure system is
designed which maximizes the chance of
observing an effect based on a theoretical
model and therefore the research leads to
a better understanding of the  mecha-
nisms of interaction.
  Four exposure facilities are described
in this report.  Each  is a large, multi-
animal exposure system available to all
the  research   staff  who   quite
frequently design  multidisciplinary
studies with these facilities. All of these
systems are located in the same "high-
bay" room which has been equipped
with an auxiliary air conditioning system
to precondition the air. The  first facility
constructed was  the 2450 MHz  CW
exposure system. 2450 MHz has become
the  defacto  reference frequency  in
biologic effects research. Probably more
work has been  done at this frequency
than at any other, and most laboratories
involved  in the research have  had a
facility at this frequency. This happened
largely for three  reasons:  (1)  the
availability of relatively low cost, high
power RF sources since 2450 MHz is an

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  ISM band  frequency  (an  ISM  band
  frequency  is  one of  a  number  of
  frequencies reserved  for use by  the
  industrial,  scientific,   and  medical
  communities by  the  F.C.C.);  (2)  the
  excellent coupling of this frequency to
  laboratory animals and (3) the projected
  explosive growth  in sales of microwave
  ovens, possibly leading to the exposure of
  a significant portion of the population to
  low-level radiation.
    The X-band exposure  facility, which
  became  operational   in   1974,  was
  designed to simulate the  RFR generated
  by radar systems. Acquisition, naval ship,
  aircraft  and small marine radars  all
  operate in the 8.5 to 9.6  GHz  range
  covered by our system. The first from the
  list above was the primary consideration
  motivating  the design of  this facility. At
  this high frequency, depth of penetration
  of the RF energy into a biological target is
  poor; however, these frequencies are in
  extensive use in the environment and the
  system provides a tool to investigate the
  effects of  high peak to average power
  ratio fields on biological organisms.
    The  100 MHz  exposure facility was
  designed to provide an irradiation facility
  in  the environmentally  significant FM
  band of radio frequencies. Radiation from
  these sources  is deliberately beamed
  toward population centers for use in FM
  radiobroadcasting and is one of the more
  significant  sources of manmade RFR in
  human  exposures1. This, coupled with
  research studies showing the resonance
  of the human body lies in the FM band2,
  were strong  arguments for  EPA to
  examine frequencies  in this  band  for
  potential biologic effects.
    The  2450  MHz  AM facility  was
  constructed for several purposes: (1) EPA
       agreed to investigate for the Department
       of Energy the biological impact of the use
       of solar power satellites which would
       collect solar energy using  satellites  in
       geosymchronous   orbit,  convert  this
       energy  to  microwave  energy  at  a
       frequency of 2450 MHz and beam it down
       to earth to be collected by large arrays of
       antennas, (2)  studies were  published
       reporting effects with low-level ampli-
       tude modulated RFR. Because virtually all
       of the U.S. population is exposed to low-
       level amplitude modulated RFR, the EPA
       has been interested in these reports.
         The systems used for  RFR  biologic
       effects  studies   are  largely  custom
       designed to tailor the system character-
       istics  for the special needs of biological
       effects research. A prime example of this
       is the power level stability of RF sources.
       In most commercial medium  and high
       power RF generators and amplifiers, the
       RF power output is seldom regulated. The
       usefulness of an airport radar or an in-
dustrial microwave oven is not se riously
compromised  if the  RF power output
drifts by 10%  to 20%. However, such a
drift is of  obvious  concern in biologic
effects studies since the absorbed energy
is directly related to the stability of the RF
source. Other features that are important
in the design  of RFR  exposure facilities
are: (1)  provisions  for  environmental
control,  (2) spectral  purity of  the  RF
source, (3) personnel safety, (4) provision
for automatically timed exposures and (5)
RF field uniformity. The latter has become
less important in recent years as the state
of the art has advanced  both in  the
determination  of  whole-body specific
absorption  rate (SAR)  and localized SAR.
As  more  becomes  known  about  the
effects of low-level amplitude modulated
RFR, control of the spectral purity of test
generators may grow  in importance. For
this reason, we have tried to characterize
the spectral content of the sources used
here where possible.
          The EPA authors Joseph S. AH fatso the EPA contact, see below) and Claude M.
            Weil are with the Health Effects Research Laboratory, Research Triangle Park,
            NC 27711.
          The complete report, entitled "Radiofrequency Radiation Exposure Facilities for
            Bio-Effects Research," (Order No. PB 83-229 591; Cost: $10.00, subject to
            change) will be available only from:
                 National Technical Information Service
                 5285 Port Royal Road
                 Springfield. VA 22161
                  Telephone: 703-487-4650
          Joseph S. AH can be contacted at:
                 Health Effects Research Laboratory
                 U.S. Environmental Protection Agency
                 Research Triangle Park, NC 27711
                                                       *U.S. GOVERNMENT PRINTING OFFICE: 1983-659-017/7148
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Agency
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Information
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