PB87-112033 Pesticide Fact Sheet Number 1. DCNA (U.S.) Environmental Protection Agency Washington, DC 9 Jan 84 U.S. Environmental Protection Aftocy Region 5, Library IPL-12J) 77 West Jackson Boulevard, 12th Floor Chicago, IL 60604-3590 L J U.S. Service ------- ,v<, t ------- $om • iQi REPORT DOCUMENTATION PAGE 1. REPORT NO. 14. TKte and SubtKI* ,EPA Pesticide Fact Sheets - No. 13 7. Author(s) EPA, Office of Pesticide Programs, Registration Division ». Performing Organization Nam* and Address US Environmental Protection Agency Office of Pesticide Programs Registration Division, TS-767C 401 M Street, S.W. Washington, D.C. 20460 12. Sponsoring Organization Nam* and Address Same as #9 PB07-1120J 1 B. Report Oat* Issued 1/9/84 «. Performing Organization Rept No 540/FS-87- Q45 10. Proract/Tasfc/Work Unit No 11. CantracttQ or GranKG) No. (C) (G) 13. Typ* of Report A Period Covered 14. IS. Supplementary Not** 16. Abstract (Umit: 200 word*) This document contai.ns up-to-date chemical information, including a summary of the Agency's regulatory position and rationale, on a specific pesticide or group of pesticides. A Fact Sheet is issued after one of the following actions has occurred. 1. Issuance or reissuance of a registration standard, 2. Issuance of each special review document, 3. Registration of a significantly changed use pattern, 4. Registration of a new chemical, or An immediate need for information to resolve controversial 5. issues relating to a specific chemical or use pattern. 17. Document Analyst* a. Detertptor* Pesticides, regulations, Chemical Information Fact Sheet, Use Patterns, Science Findings b. Identlfi*r*/Op*n-End«d Terms c. COSATI Reid/Group Av.liability SUtemenl Publicly Available 1*. Security Claw (Thl* Report) Unclassified murtty Clam» rthlf ^ra««) classified 21. No. of Pag** 22. Price (Set ANSI-Z39.18) See Instruction* on rr*v*r»* OPTIONAL FORM 272 (4-77) (Fomwrty NTIS-35) Department of Commerce ------- United Stats* office of PwtickJw and Toxic Substances Environmental Protection Office of Pesticide Programs (TS-766CI Washington. DC 20460 &EPA Pesticide Fact Sheet Name of Chemical: Reason for Issuance: Date Issued: Fact Sheet Number: ^°\3 1. Description of the Chemical: Generic name: 2,6-dichloro-4-nitroaniline Gorman name: dicloran Trade name(s): DClft, botran, ditranil, allisan, and resisan EPA Shaughnessy code: 031301 Chemical abstracts service (CAS) number: 99-30-9 Year of initial registration: 1961 Pesticide type: Funoicide Chemical fanily: Nitroanaline U.S. and foreign producer: Utriohn Company 2. Use patterns and formulations: Application sites: DCNA is used to control a variety of pre- and cost-harvest diseases on fruit and veoetable croos. Current mator use sites include peaches, oraoes, lettuce anr* celery. It is a orotectant to ornamentals and veget- able seeds. It is also reaistere/* for use on cotton, a number of ornamentals, a seed-piece die for sweet potatoes, a oeanut see^ treatment, and in greenhouses on cucumbers, lettuce, rhubarb, and tomatoes. Tyues of formulations: Formulated products are 4, 5, 6, 8, 10, 12, 15, 20, 30, 35, or 50% dusts: 48.8 or 75* wettable powders: 9 or 30% flowable concentrates: as 0.5 or 3% ready-to-use liouids: a 3% formulation in fruit wax: and a 0.2% impregnated fruit wrap. DCTv may be formulated with other pesticides such as caotan, bencmyl, and parathion. It is not compatable with some oil-based pesticides. Types and Methods of application: DCN& nay be applied as pre-harvest and post-harvest uses on fruit and vegetable crops; seed and ornamental protectant. In the field, DCNA can be applied by ground and aircraft. DCNA can be applied as a post-harvest dip, spray, or dust to sane fruits and vegetables and as a protectant to ornamental crops orior to storage and shinment. Application rates: 1.5 to 30 Ib/A. Usual Carriers: either water or wax as diluent ------- 3. Science Finding?: Summarv science statement: / TTnere are extensive data cjaos for DOJk. No human toxicolooica". \^ hazards of concern, other thar inducement of skin photosensitivitv, and possible ocular toxicity, have beer, identified in studies reviewed by the Aoencv for this standard. Ihe Agency has no information that indicates continued use will result in any unreasonable adverse effects to nan or his environment during the time required to deveioo the data. Chemical characteristics: DCJft is a vellow, crystalline powder. The solubilitv of DOR in ethanol is 0.2% at 20°C and its melting point is 192-194°C. The chemical does not present any unusual handling hazards. Toxicology cnaracteristics: Acute toxicology studies: Acute Oral ID$Q in rats: >10,000 mg/kg, Toxicity category T\' Acute Dermal L&JQ in rabbits: >2.0 q/kq, "Toxicity category m Acute Inhalation ££55 in rats: >2 mq/1, Toxicitv catecrorv m EXZNA does not induce skin or eve irritation - Itaxicity cateaorv Til DCNfc was found to be a skin sensitizer and may induce phototoxicitv due to the oresenc*? of aniline in its corcostior.. Chronic toxicology studies: fftere is insufficient data to assess the subchronic dermal or subchronic inhalation hazard Chronic toxicitv in rats: NDEL = 100 pan: LEL = 3000 DOT Oncoaenicitv study in rats: no tumors at 3000 par Teratoaenicitv in rabbits: no abnormalities at 1000 DOT Reoroduction in rats: ND^ = ion ppn Mai or routes of exposure: Subchronic dermal or respiratory contact Environmental characteristics: Data are insufficient to fully assess the environmental fate of DQft Ecological characteristics: Hazards to fish and wildlife: Avian dietary ££50: Mallard duck - 9500 par, Bobwhite quail - 2120 pprr Pish I£50: >1.08 pprr. Aquatic invertebrates LCso: 2.3 par, Potential problems for endangered species: Hiil be reassessed after review of environmental fate data. Physiological and biochemical behavioral characteristics: Mechanian of pesticidal action: Itxxjght to be a non-specific inhibitor of cell division and can effect nuclear stability. General metabolism in rats: 1.7 and 8 no/taj body weight was absorbed, no body tissue accumulation was detected. ------- Tolerance assessment: List of crccc and tolerances dr. par.): annco'is fore and post Hi 2- , snapoeans 2C, blackDemes IE, bovsenoemes 15, carrots (post H 1" celery 15, sweet cherries {ore and post H) 2C, cotton seeci C.I, cucumoers 5, endive 30, garlic 5, arapes 10, kiwifruit (post Hi 2C, lettuce 10, nectarines (ore and post H) 2C, onions 5, peaches (pre and post H) 20, plums (fresh, orunes) (pre and post H) 15, potatoes 0.25, raspberries 15, rhubaro 1C, sv^et potatoes (post H) 10, tomatoes 5. Tolerance reassessment: Due to the absence of oertinent data, the Agency is unable to complete its reassessment of DCNA tolerances, 4. Summary of Regulatory Position and Rationale: Use classification: general use Unique label warnino statements: Manufacturino-use labels must contain the statements "Do not discharge into lakes, streams, ponds or public waters unless in accordance with NPDES permit. Por guidance contact your regional office of EP^.P 5. Sunroary of Major Data Gaps: Product chemistry: data due ~ ^8- Identitv of ingredients Statement of ccnoosition Discussion on formation of contaminants Preliminary analysis Certification of 1 units Analytical methods Odor Density, bulk density, or specific gravity Solubility Vapor pressure Dissociation constant Octanol/water partition coefficient - Toxicology: studies due 1/88 Ocular toxicity Photosensitization 21-day subchronic dermal Oncogenicitv in mouse (in Drogress) Tsratogenicity (in progress) -Mutagenicity testing Wildlife and Aquatic oraanisms: studies due 1/88 Single-dose oral ID^Q on one avian species Acute 48 hour toxicitv study on a freshwater invertebrate Fish embryo-larvae and/or aquatic field studies may be required depending on environmental fate data 3 ------- Rnvironme-.tal Fate: studies dje 1/8? Hydrolvsis stume? Pnotcrieara.-iatior. stales ir water Photodearedatior studies or soil Aerobic soil metaboiisrr study Anaerobic soil metabolism studv Leachina and adsorption/desorntior. studies Laboratorv volatility studies Terrestrial field dissioation studies LongtetJT: field dissipation studies Confined accumulation studies on rotational crope Laboratorv studies of pesticide accumulation in fish Rentry Protection: Data reouirement pending on results of toxicological testina Residue Chemistry: studies due 1/88 Nature of residue for plants and animals Residue analytical method for animals Storage stability data Crop field trials for potatoes, sweet potatoes, onions, apricots, cherries, nectarines, reaches, Plums,black- berries, boysenbetries, raspberries, kiwi Processed food^eec for potatoes, tcroatoes, cottonseed 6. Contact persor. at F?'. Mr. Henry K. Jacob-/ Environnental Protection Agency FUnaicide-HerE'icide Branch (TS 76~-C: 401 K St., SW Washinaton, D.C. 2046H (703) 557-190C DISQAIM15R: The information oresented in this Chemical Information Fact She-t is for informational puposes only and may not be used to fulfill' data requirements for pesticide registration and rereqistration. ------- |