------- ------- United States Office of Pesticides Environmental Protection and Toxic Substances Agency . (H7501C) 540/FS-89-060 •r/EPA Pesticide Fact Sheet Name of Chemical: SULKLURAMID Reason for Issuance: CONDITIONAL REGISTRATION - NEW CHEMICAL Date Issued: MARCH 23, 1989 Fact Sheet Number: 205 1. DESCRIPTION OF THE CHEMICAL Generic Nane: N-Ethyl Perfluorooctanesulfonamide Common Name: Sulfluraraid Trade Name: GX-071 EPA Shaughnessy Code: 128992 (OPP Chemical Codes) Chemical Abstracts Service (CAS) Number: 4151-50-2 Year of Initial Registration: 1989 Pesticide Type: Insecticide Chemical Family: Fluorinated Sulfonamide Producer: Griffin Corporation of valdosta, GA 2. USE PATTERNS AND FORMULATIONS Target pests: Roaches, Ants Registered Uses: indoor roach trap, indoor ant trap, technical manufacturing-use product. Methods of Application: Child resistant bait station. Formulations: Technical, bait station. ------- -2- 3. SCIENCE FINDINGS Chemical Characterisiti.es; Physical State: Solid Crystals Color: White Odor: None Melting point: 96 degrees C Vapor Pressure: 4.3 x 10~7 mm Hg at 25 degrees C 9.99 x 10-7 mm HG at 34 degrees C Density: 0.1485 g/ml at 25 degrees C Storage Stability: Stable for a minimum for 1 year when stored in a polyethylene bag under ambient conditions. Octanol/Water Partition Coefficient: Pow = 3.10 Flammability: NR Solubility: The Technical Grade of the Active Ingredient does not dissolve or disperse in water. Toxicology Characteristics; Technical Formulation: GX-071 Technical EPA File Symbol 1812-327 Acute Oral Toxicity-Rat : LD^ = 500 mg/kg Toxicity Category IV Single Dose Dermal Toxicity-Rabbits : 1,050 > Toxicity Category III Primary Eye Irritation-Rabbits Not considered an eye irritant. ------- -3- primary Dermal Irritation-Rabbits Mild skin irritant. Score of 0.13. Delayed Contact Sensitivity - Guinea Pigs Data gap. Salmonella/Mammalian Activation Gene Mutation Assay Negative up to the limits of solubility (624 ug/plate and above) and dosing (tested up to 10,000 ug/plate) Sister Chromatid Exchange in Chinese Hamster Ovary Cells Negative for inducing sister chromatid exchange in vitro. Rat Primary Hepatocyte unscheduled DNA Synthesis Assay Data gap. End-Use Formulations Raid Roach Controller II EPA Registration Number 1812-329 Acute Oral Toxicity Study - Rat No deaths occured following oral exposure to 5 grams/kg. Raid Ant Controller II EPA Registration Number 1812-330 Acute Oral Toxicity Study - Rat No deaths occured following oral exposure to 5 grams/kg. Ecological Characteristics; Avian Dietary Mallard Duck — > LC50 = 165 ppm Bobwhite Quail — > l£$0 = 460 ppm Avian Oral LD50 Bobwhite Quail — > 1X50 = 473 mgAg ------- -4- Freshwater Fish ££50 Rainbow Trout —> Normal 1X50 > 10 ppm Measured LC50 > 2 ppm Acute LC50 Freshwater Invertebrate Daphnia pulex —> Normal LC50 > 10 ppm Measured LC50 > 0.21 ppm Summary of Regulatory Position and Rationale - The Agency has determined that it should allow the conditional registration of sulfluramid for indoor nonfood use in bait stations to control ants and roaches. Adequate data are available to assess the acute toxicological effects of sulfluramid to humans. - Data Gaps: Primary Hepatocyte Unscheduled DNA Synthesis Dermal Sens itizat ion - This registration is conditionally approved with an expiration date of September 15, 1990. 7. CONTACT PERSON AT EPA Phillip 0. Hutton Product Manager (17) Insecticide Rodenticide Branch Registration Division (H7505C) Office of pesticide programs Environmental protection Agency 401 M Street, S. W. Washington, D. C. 20460 Office location and telephone number: Room 207, Crystal Mall |2 1921 Jefferson Davis Highway Arlington, VA 22202 (703) 557-2690 DISCLAIMER: The information in this Pesticide Fact Sheet is a summary only and is not to be used to satisfy data requirements for pesticide registration and reregistration. Contact the Product Manager listed above for further information. ------- |