n/,ql cy             United States
\jtn? i •               Environmental Protection
• A81               Agency
G81

1987
&EPA       Research and
             Development    600SR87io4
            GULF BREEZE LABORATORY

            TITLES AND ABSTRACTS

            1986, I987, IN PRESS AND

            IN REVIEW PUBLICATIONS
            Prepared by

            Environmental Research
            Laboratory
            Gulf Breeze FL 32561

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                                DISCLAIMER

     This document is intended for Agency use only.  Mention of trade
names or commercial products does not consitute endorsement or recommendation
for use.

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TABLE OF CONTENTS                                             PAGE
ABOUT THIS PUBLICATION	    V

TITLES AND ABSTRACTS	     1

KEYWORD TITLE INDEX	    50

AUTHOR INDEX	    59
                                             U.S.  Environmental Protection
                                             Region  5, Library (5PL-16)
                                             X7'0  S.  Dearborn Street, Room 1
                                             Chicago,  IL   60604

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                     About This Publication
This report represents an effort to provide agency administators,
managers, and scientists with the most timely information about
availability and content of the Gulf Breeze Laboratory research
program.  Full text, a report copy or a reprint can be provided
by phone or written request to:  Elizabeth Pinnell, Librarian
 (904) 932-5311 or  (FTS) 686-9011.  Requests will be accepted for
publications listed without an asterisk beside the contribution
number.  Requests  for items still in review or in press will
be retained and filled upon publication.  If an item is available
from NITS, Springfield, VA, the order number follows the citation.

This format is intended as a service to agency users who may
wish not only to examine the title and abstract of a publication
or a report, but also to know of the availability of technical
documentation.  To facilitate usage, publications are indexed by
title keywords and author.
                                             Henry F. Enos
                                        laboratory Director
Preparation Date:
July 1987

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Abel,  Daniel  C.,  Christopher  C.  Koenig,  and  William  P.   Davis.   1987.
Emersion in the Mangrove Forest Fish Rivulus marmoratus: A Unique Response to
Hydrogen Sulfide.  Environ. Biol. Fishes.  18(1):67-72.  (ERL,GB 554).

   Ihe  mangrove  forest fish Rivulus  marmoratus  (Cyprinodontidae)  has
   frequently been observed out of water, a phenomenon generally
   attributed  to habitat drying. We tested the hypothesis that  hydrogen
   sulfide,  a substance characteristically found in  their  environment,
   can  serve  as  a  stimulus for emersion. In the  field  we  found  R.
   marmoratus in water with low to moderate levels (less than 250 ppfo)  of
   H2S.  In the laboratory, R. marmoratus leaped from water  contaminated
   with  H2S at ecologically relevant concentrations (median response  at
   123  ppb). Aquatic hypoxia did not induce emersion, but  prey  capture
   did.  Oxygen  consumption  by  both  juveniles  and  adults  decreased
   significantly  in air (27 and 25%, respectively).  Our results  suggest
   that avoidance, of H2S and the ability to survive terrestrial
   conditions  enable this species to permanently occupy an area  of the
   forest unavailable to other fishes. Furthermore, because a variety  of
   stimuli  lead  to emersion in R. marmoratus,  terrestriality  in  this
   species  is likely a generalized response to environmental  stress  as
   well as a means of exploiting terrestrial resources.

Ahearn, D.G., and S.A. Crow. In review. Fungi and Hydrocarbons in the  Marine
Environment.  In:  Proceedings  of  the  4th  International  Marine  Mycology
Symposium.  S.T.  Moss, editor, Cambridge University Press,  London.   (ERL,GB
X507*).
Avail, from OTIS, Springfield, VA: PB86-109964

   Hydrocarbons  from  various sources—anthropogenic  pollution,  marine
   seeps, marine algae, atmospheric fallout and terrestrial runoff—enter
   the ocean daily. These complex hydrocarbon mixtures are dispersed and
   degraded  by abiotic and biogenic processes. Ihe rate  of  degradation
   and  the significance of microbial activities in the fate  of  oceanic
   hydrocarbons  vary  with  environmental conditions  and  the  type  of
   hydrocarbon.  Most  commonly,  bacteria  are  considered  the  primary
   degraders,  with algae and fungi having minor roles. Although  implied
   in a number of cases, the degradation of complex hydrocarbon  mixtures
   by a successional microflora containing temporally isolated
   populations  of  bacteria and fungi, has  been  inadequately  studied.

Alexander, Martin.  In press. Anomalous Effects of Concentration on
Biodegradation of Organic Chemicals.  Appl. Environ.  Microbiol.  1%>.
(ERL,GB X4S1*).

   Ihe  purpose of this review is to show that erroneous conclusions may
   be  reached from studies or routine tests done with organic  chemicals
   at  the levels often employed for predicting chemical fate in  nature.
   Ihese errors in extrapolation from high to low concentration may occur
   in  routine  evaluations  of biodegradation,  careful  assessments  of
   kinetics  or the establishment of products formed in waters, soils  or
   sediments.
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Barkay, Tamar. In review. Adaptation of Aquatic Microbial Communities to Hg2+
Stress.  Appl. Environ. Microbiol.  23p.  (ERL,GB 608*).

   The  mechanism  of  adaptation to Hg2+ in four  aquatic  habitats  was
   studied  by correlating microbially mediated Hg2+ volatilization  with
   the adaptive state of the exposed communities. Structural and
   functional parameters indicated that adaptation of all four
   communities  was  stimulated  by exposure to  Hg2+.  In  saline  water
   communities, adaptation was associated with rapid volatilization after
   an  initial  lag  period. This mechanism,  however,  did  not  promote
   adaptation  in  as  freshwater  environment,  where  Hg2+  volatilized
   slowly,  regardless of the adaptive state of the microbial  community.
   Distribution  of the mer operon among represenetative colonies of  the
   cxDmmunities  was  not related to adaptation to  Hg2+.  Thus,  although
   volatilization is a mechanism which enables some microbial communities
   to  sustain their functions in Hg2+ stressed environments, it  is  not
   coded  for  by the gene system that mediates this  mechanism  in  pure
   cultures.

Barkay,  T.,  D.  Chatterjee,  S. Cuskey, R.  Walter,  F.  Genthner,  and  A.
Bourquin. In review. Bacteria and the Environment.  In:  Revolution in
Biotechnology.  International  Council of  Scientific  Unions.  22p.  (ERL,GB
604*).

   Microorganisms with new functions can be constructed in the laboratory
   by gene cloning. This paper discusses the potential of a powerful tool
   for  environmental  management:  new  strains  to  control  pests,  to
   increase  yields,  and to degrade noxious pollutants.  Approaches  and
   methods are described for risk assessment based on the experiences and
   findings in microbial ecology. However, risk assessment criteria  have
   yet  to  be  established due to the unknown  and  potentially  harmful
   effects  of  the introduced organisms on the  receiving  environments.

Barkay,  Tamar,  and Gary Sayler. In review. Gene Probes as a  Tool  for  the
Detection of Specific Genomes in the Environment.  Presented at the 10th ASTM
Symposium  on  Aquatic Toxicology and Hazard Assessment, May 4-6,  1986,  New
Orleans, IA.  16p.  (ERL,GB 578*).
Avail, from NTTS, Springfield, VA: PB87-102505.

   Gene probes hold a great promise as a tool in environmental  sciences.
   They  may  be used to detect specific genotypes, to follow  gene  flow
   process,  to  delineate complex taxonomic aggregates  and  to  monitor
   genetically  engineered organisms in the environment. The  sensitivity
   of the method is currently limited by experimental procedures and  its
   specificity depends on the nature of the DNA sequences used as  probes
   and  the  efficacy of lysing methods,  yariable  genetic  determinants
   which  code  for  the same trait determine the  universality  of  gene
   probes. Finally, the method is highly feasible in terms of cost, speed
   and expertise. Current and future developments in molecular  microbial
   ecology are likely to contribute toward the improvement of the probing
   methodology for the full realization of its potential in environmental
   sciences.
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Borthwick,  Patrick  W.  1986.  Effects of Salinity Change  on  Acute  Lethal
Responses of Bay Mysids (Mysidopsis bahia) to Three Insecticides.
EPA/600/X-86/272*, U.S. Environmental Protection Agency, Environmental
Research laboratory, Gulf Breeze, FL.  7p.

   In this study we investigated the influence of salinity change on  the
   acute  toxicities of three insecticides to the bay  mysid  (Mysidopsis
   bahia).  Salinity  is a principal environmental variable in  estuarine
   waters.  Bay ntysids subjected to a 50-minute salinity change and  high
   (32 o/oo) and low (10 o/oo) salinity seawater were approximately three
   times more sensitive to fenvalerate (synthetic pyrethroid insecticide)
   compared  to  mysids exposed at the reference (culture)  salinity  (21
   o/oo).  At  low salinity, ntysids exposed  to  endosulfan  (chlorinated
   insecticide) were almost 4 times more sensitive; high salinity  caused
   a slight sensitivity increase. Fenthion (organophosphate  insecticide)
   toxicity, least affected by salinity, was unchanged at high  salinity,
   and only slightly more toxic at low salinity. Evidence from this study
   indicated  that salinity change may reduce an organism's tolerance  to
   toxic insecticides.

Bourquin,  Al  W.  1986.  Biotechnology  Aquatic  Risk  Assessment  Research.
EPA/600/X-86/235*, U.S. Environmental Protection Agency, Environmental
Research laboratory, Gulf Breeze, FL.  346p.

   This  internal status report and attached publications summarizes  the
   initial research efforts in the Aquatic Biotechnology Risk  Assessment
   Research  Program at URL/Gulf Breeze. The research was  undertaken  in
   response  to  an  OPTS need to more fully  understand  the  ecological
   impact of the deliberate release of genetically engineered
   microorganisms  into the aquatic environment. The research covered  in
   this  report emphasizes the most recent developments in detection  and
   enumeration  technology for specific microorganisms and  specific  ENA
   segments. The report summarizes the development of
   immunoepifluorescence  microscopy techniques for detecting viable  but
   nonculturable  microbes  and  the  use of  ENA  probes  for  detecting
   specific  segments  of  genetic  materials  in  environments  and  the
   development  of a laboratory method to determine genetic  exchange  in
   environmental systems. The report summarizes and contains 17
   peer-reviewed publications and reports produced by the ERL/Gulf Breeze
   program during the period from June 1985 to September 1986.

Brayton,  P.R.,  and R.R. Colwell. In review. Fluorescent  Antibody  Staining
Method for Enumeration of Viable Environmental Vibrio cholerae.  J.
Microbiol. Methods.  12p.   (ERL,GB X521*).

   A  membrane filtration method has been developed which is  useful  for
   enumeration  of  viable  Vibrio cholerae  01  in  environmental  water
   samples by immunofluorescent staining. The samples are incubated  with
   yeast  extract  and nalidixic acid. Substrate responsive  cells,  i.e.
   viable cells, elongate and after staining with specific antiserum  and
   fluorescein  conjugate,  viable  V. cholerae  cells  appear  as  long,
   peripheral  fluorescent  green banded bacilli when  viewed  under  the
   microscope.  Using an ocular reticule, the number of viable cells  per
   ml  can  be calculated. The procedure has been adapted  for  use  with
   other bacterial species if specific antisera is employed.
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Brusca,  J.,  M. Summers, J. Couch, and  L.   Courtney.   1986.   Autographa
californica  Nuclear  Polyhedrosis  Virus Efficiently  Enters  but  Does  Not
Replicate  in  Polikilo  Thermic  Vertebrate  Cells.   Intervirology.
26:207-222.  (ERL,GB 558*).

   The  host  range of the insect virus  Autographa  californica  nuclear
   polyhedrosis virus (AcMNPV) was examined. AcMNPV could not initiate  a
   productive infection in frog, turtle, trout,  or moth cell lines. After
   exposure  to  AcMNPV,  neither viral DMA nor RNA  synthesis  could  be
   detected in these cell lines when assayed by dot-blot  hybridizations.
   Entry  of viral DNA to the nucleus, however,  was as efficient  in  the
   nonpermissiye  cell lines as it was in a permissive insect cell  line.
   Electron  microscopy  revealed numerous AcMNPV  nucleocapsids  in  the
   cytoplasm  of  the nonpermissive cell lines is therefore  at  a  stage
   subsequent to viral entry to the nucleus.

Capuzzo, Judith M. In review. Development of Physiological Indices to Predict
the Effects of Chronic Pesticide Exposure on Zooplankton Populations.  Aquat.
TOxicol.  41p.  (ERL,GB X511*).

   The effects of the pyrethroid pesticide fenvalerate and the
   organophosphate  pesticide  fenthion on  planktonic  crustaceans  were
   investigated in continuous-flow bioassays. Fenvalerate was more  toxic
   than  fenthion in acute bioassays with 96-h LC50 values  ranging  from
   5.4  ng/1  for Stage I larvae of Homarus americanus to 46.0  ng/1  for
   adult  Heteromysis formosa; LC50 values for adult Acartia  tonsa  were
   14.7  ng/1,  fenvalerate and 102.5 ug/1, fenthion.  Metabolic  changes
   paralleled  delays  in  development for larvae of  H.  americanus  and
   reductions  in  egg production and larval viability of A.  tonsa.  The
   most  sensitive indicators of acute toxic response of Acartia to  both
   pesticides  were  gross and net growth efficiencies (KL  and  K2)  and
   instantaneous birth rates, parameters which integrate metabolic
   responses, survival, and reproduction. Reductions in both bioenergetic
   parameters  and  birth rates were evident with sublethal  exposure  to
   both  contaminants. Disruptions in reproduction and  development  were
   also  observed  in  chronic assays of fenvalerate  on  Acartia  tonsa.
   Chronic  exposure  to  0.6  ng/1 also  resulted  in  reproductive  and
   developmental  impairment,  although some second  generation  copepods
   developed to maturity.

Chatterjee, Deb K., and A.W. Bourquin.  1987.  Metabolism of Aromatic
Compounds by Caulobacter crescentus.  J. Bacteriol.  169(5):1993-1996.
(ERL,GB 591).

   Cultures of Caulobacter crescentus were found to grow on a variety  of
   aromatic  compounds.  Degradation of benzoate,  p-hydroxybenzoate  and
   phenol  was  found  to  occur  via  B-ketoadipate.  Induction  of  the
   degradative  enzymes  such  as  benzoate,  1,2-dioxygenase,  the  ring
   cleavage  enzyme,  catechol  1,2-dioxygenase,  and  cis,  cis-muconate
   lactonizing  enzyme appeared similar to the control mechanism  present
   in Pseudomonas. Both benzoate 1,2-dioxygenase and catechol
   1,2-dioxygenase  seem to have stringent specificities as  revealed  by
   their  action towards substituted benzoat.es and substituted  catechols
   respectively.  The potential degradative abilities of Caulobacters  is
   discussed.
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Clark, James R., James M. Patrick, Jr., James C. Moore, and Jerrold Forester.
1986.  Accumulation of Sediment-Bound PCBs by Fiddler Crabs.  Bull.  Environ.
Contam. Toxicol.  36:571-578.  (ERL,GB 533).

   Polychlorinated  biphenyls  (PCBs) have been, and continue to  be,  an
   ecological  problem  because of their  environmental  persistence.  In
   aquatic systems, PCBs sorb to organic matter, accumulate in sediments,
   and  contaminate  food chains. Because of the  potential  for  causing
   reproductive impairment, PCBs in aquatic food chains pose a threat  to
   human  and  other predators that consume fish and  shellfish.  Fiddler
   crabs accumulate PCBs from contaminated sediments and detritus and can
   transfer them to aquatic, avian, and terrestrial food webs when preyed
   upon by fishes, birds, and small mammals.  The primary objective of our
   research  was  to characterize rates of PCB uptake and  depuration  by
   fiddler crabs in a simulated spoil bank habitat that contained PCBs in
   weathered  sediment.  Also, we examined whether the  concentration  of
   PCBs  in  substrates  affected  bioaccumulation  by  mixing  PCB-laden
   sediments with clean sand. In a pilot study, we tested Uca  pugilator,
   an  inhabitant of relatively dry and sandy areas, and U. minax,  which
   inhabits wetter and muddier substrates, to determine if species differ
   in PCB uptake and depuration rates.

Clark,  James R., Patrick W. Borthwick, Larry R. Goodman, James  M.  Patrick,
Jr.,  Emile  M. Lores, and James C. Moore.  1987.  Comparison  of  Laboratory
Toxicity  Test Results with Responses of Caged Estuarine Animals  Exposed  to
Fenthion  in the Field.  Environ. Toxicol.  Chem.  6:151-160.   (ERL,GB  545).

   Acute, lethal effects of fenthion  (an organophosphate insecticide)  on
   mysids  (Mysidopsis  bahia), grass shrimp (Palaemonetes  pugio),  pink
   shrimp (Penaeus duorarum), and sheepshead minnows (Cyprinodon
   variegatus)  were  determined  in laboratory  tests  and  after  field
   applications.  Exposure  at four field sites  ranged  from  short-term
   exposures  (equal to or less than 12 h) of rapidly decreasing  fenthion
   concentrations  to extended intervals (greater than 72 h) with  slowly
   increasing  or decreasing fenthion concentrations.  Laboratory-derived
   LC50s  provided  a  reliable benchmark for  predicting  acute,  lethal
   effects  of  fenthion  on caged animals in the  field  when  exposures
   persisted  for  24  h  or more  but  overestimated  the  toxicity  for
   exposures less than 24 h. laboratory pulse-exposure tests with rapidly
   changing  concentrations  for 12 h were predictive  of  nonlethal  and
   lethal effects observed for short-term field exposures.
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Clark, J.R., P.W. Borthwick, L.R. Goodman, J.M. Patrick, Jr., E.M. Lores, and
J.C. Moore. In review. Effects of Aerial Thermal Fog Applications of Fenthion
on  Caged Pink Shriirp, Mysids, and Sheepshead Minnows.  J. Am. Mosg.  Control
ASSOC.  14p.  (ERL,GB 602*) .

   Mosquito  control  applications  of fenthion  by  aerial  thermal  fog
   equipment were studied at two sites in Collier County, FL, for  sprays
   that  occurred  on  20  and 23 June 1984.  Acute,  lethal  effects  of
   fenthion deposited in these estuarine habitats were assessed for caged
   pink shriup (Penaeus duorarum), mysids (Mysidopsis bahia), and
   sheepshead  minnows  (Cyprinodon variegatus). At Site 1, along  a  bay
   with substantial dilution and tidal mixing, fenthion concentrations of
   1.5  ug/1 and 0.29 ug/1 were recorded immediately after  both  sprays.
   Concentrations  decreased  to less than or equal to 0.020  ug/1  12  h
   post-spray  and  no mortality was observed for caged pink  shriup  and
   mysids.  Site  2  was along a residential canal  system  that  offered
   limited  dilution and mixing. Measurable concentrations  (greater  than
   0.038  ug/1) of fenthion persisted at this site for 4  days.  Fenthion
   concentrations  in surface waters were toxic to caged pink shrimp  and
   mysids  after  both sprays; maximum concentrations were 2.6  ug/1  and
   0.51 ug/1. Caged sheepshead minnows were not affected by the sprays at
   either site.
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Clark, J.R., L.R. Goodman, P.W. Borthwick, J.M. Patrick, Jr., J.C. Moore, and
E.M. Lores.  1986.  Field and Laboratory Toxicity Tests with Shrimp,  Mysids,
and  Sheepshead  Minnows Exposed to  Fenthion.  In:  Aquatic  Toxicology  and
Environmental  Fate: Ninth Volume, ASTM STP 921.  T.M. Poston and  R.  Purdy,
editors,  American  Society  for Testing  Materials,  Philadelphia,  PA.  pp.
161-176.   (ERL,GB 539).

   We  conducted  a series of laboratory  pulse-exposure  experiments  to
   model  short-term  field  exposures of  two  representative  estuarine
   crustaceans, Penaeus duorarum and Mysidopsis bahia, to the
   organophosphate insecticide fenthion. These tests established  acutely
   lethal  and nonlethal concentrations during pulse exposures. The  data
   are  necessary for interpretation of responses of test animals in  the
   field  when  fenthion concentrations changed rapidly  with  time.  The
   toxicity  of  fenthion to caged pink shrimp,  mysids,  and  Sheepshead
   minnows  (Cyprinodon variegatus) was determined in the field  following
   two aerial applications separated by 72 h, to control adult  saltmarsh
   mosquitoes. At one estuarine site, initial concentrations of  fenthion
   in water were 1.5 ug/L following Spray 1 and 0.29 ug/L after Spray  2.
   Within  12  to 24 h, however, fenthion was not detectable   (less  than
   0.01  ug/L) because of rapid tidal flushing and high dilution at  this
   site.  Although  initial exposures approached or  exceeded  laboratory
   24-h  LCSOs  for pink shrimp (0.40 ug/L) and mysids   (0.42  ug/L),  no
   mortality  occurred  among  caged animals. At a second  site  along  a
   residential saltwater canal with limited tidal flushing and  dilution,
   initial  concentrations  of fenthion were 2.6 ug/L (Spray 1)  and  0.5
   ug/L  (Spray 2). Within 12 to 24 h post-spray, fenthion  decreased  to
   0.4  ug/L  (Spray 1) and 0.14 ug/L (Spray 2) and continued to  diminish
   during the next 48 to 72 h. These concentrations approximated the  48-
   and  72-h LCSOs for pink shrimp (0.22 ug/L and 0.15 ug/L)  and  mysids
    (0.37  ug/L  and 0.18 ug/L). All exposure  concentrations  were  three
   orders  of magnitude below the 24-h LC50 for Sheepshead minnows   (1900
   ug/L)  and no mortality occurred among caged fish. By deploying  caged
   pink  shrimp  and mysids daily, before and after each spray,  in  situ
   exposure regimes varied for each group and resulted in responses among
   caged  test  populations that ranged from no observed effect  to  100%
   mortality.  The responses of caged pink shrimp and mysids  exposed  to
   slowly  changing concentrations of fenthion in the field were  similar
   to  what  would  have been predicted based on  laboratory  tests  that
   established 24-, 48-, and 72-h LCSOs. Laboratory pulse-exposure  tests
   were predictive of no-effect and effect pulse exposures in the  field.
   These  comparisons demonstrated that predictions of fenthion  toxicity
   based on laboratory test results were valid when field and  laboratory
   exposure regimes were similar.
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Clark, James R., and James M. Patrick, Jr. In review. Toxicity of
Sediment-Incorporated Drilling Fluids to Lancelets (Branchiostoma caribaeum).
Mar. Pollut. Bull.  9p.  (ERL,GB 607*).

   The  24,  96, or 168-h LCSOs of four used drilling  fluids  or  barite
   incorporated  into  sediment were determined in  toxicity  tests  with
   lancelets (Branchiostoma caribaeum), a benthic chordate. The number of
   lancelets that did not burrow into contaminated sediments was used  to
   calculate  ECSOs  at  the  same  times  that  LCSOs  were  determined.
   Observations of the burrowing behavior allowed quantitation of effects
   after  24-h exposures to each of the drilling fluids whereas  lancelet
   mortality was sufficient to calculate 24-h LCSOs for only one drilling
   fluid.  Drilling fluids were less toxic to lancelets when incorporated
   into sediments than to mysids (Mysidopsis bahia) or benthic
   invertebrate communities in water-column exposures.

Clark,  James R., James M. Patrick, Jr., James C. Moore, and Emile M.  Lores.
1987.  Waterborne and Sediment-Source Toxicities of Six Organic Chemicals  to
Grass  Shrimp (Palaemonetes pugio)  and Amphioxus  (Branchiostoma  caribaeum).
Arch. Environ. Contam. Toxicol.  16:401-407.  (ERL,GB 575*).

   Grass shrimp (Palaemonetes pugio) were exposed to either waterborne or
   sediment-source concentrations of fenvalerate, cypermethrin,
   1,2,4-trichlorobenzene  (TCB), tributyltin oxide (TBTO),  triphenyltin
   oxide, and di-n-butylphthalate in static or flow-through test systems.
   Similarly, amphioxus (Branchiostoma caribaeum) were tested with
   fenvalerate, TCB, and TBTO. The LC50 and no-effect and 100%  mortality
   concentrations are reported from 96-hr and 10-day tests. The  toxicity
   of contaminated sediments could be explained by chemical  partitioning
   into overlying or interstitial water. Amphioxus is not recommended  as
   a  routine  test species because of (1) difficulty  in  distinguishing
   severely  affected from dead animals,  (2) inability to  determine  the
   status  of  burrowed animals without disrupting  sediment,  (3)  their
   relative  lack of sensitivity in acute exposures to  toxic  chemicals,
   and  (4)  difficulty in routine collection of  sufficient  numbers  of
   animals.  Grass  shrimp,  however, are useful as  an  epibenthic  test
   species for waterborne and sediment-source toxicants.
                                 PAGE   8

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Colwell, R.R., and D.J. Grimes.  1986.  Evidence for Genetic Modification  of
Microorganisms Occurring in Natural Aquatic Environments.  In:  Aquatic
Toxicology  and Environmental Fate: Ninth Volume, ASTM STP 921.  T.M.  Poston
and R. Purdy, editors, American Society for Testing and Materials,
Philadelphia, PA.  pp. 222-230.  (ERL,GB X518*).

   Recent work at a deep ocean dump site off the coast of Puerto Rico has
   shown  that  changes  in the microbial populations  of  the  receiving
   waters  can  be  detected, that is,  changes  in  bacterial  community
   structure,  over  and above seasonal effects,  have  been  documented.
   Microbial iirpact of the dumping of wastes occurs at three levels which
   can  be  measured. These include the initial effects at  the  time  of
   dumping,  followed  by  sustained community  structural  changes,  and
   finally  genetic modification of the natural population  evidenced  by
   increased  incidence  of  plasmids. The  ocean  dumping  studies  were
   augmented  by  examination of the incidence of  plasmids  in  bacteria
   isolated  from  samples collected at other locations in  the  Atlantic
   Ocean,  including  outfall samples collected at Barceloneta,  PR,  off
   shore samples collected at an outfall off Ocean City, MD, and a  clean
   unpolluted site. The incidence of plasmids could be significantly  and
   dramatically related to influx of sewage. Thus, environmental  changes
   already  occur as a result of entrance of allochthonous material  into
   the  marine  environment. It is clear that baseline  measurements  are
   necessary to determine genetic alteration already taking place, before
   effects  of  entry of genetically engineered organisms to  the  marine
   environment can be determined.

Colwell, Rita R. In review. Release of Genetically Engineered  Microorganisms
into the Environment.  Microbiol. Sci.  19p.  (ERL,GB X517*).

   The  survival,  fate,  and  effects of  GEM  in  the  environment  are
   discussed.  Because  organisms, when released, cannot be  recalled  or
   always  controlled, it is imperative that a full understanding of  the
   risks be known. Predictive ecology must include the new  subdiscipline
   of  molecular microbial ecology, if the need for information prior  to
   release  of  GEM  is to be met. One  important  aspect  of  deliberate
   release  to be considered is the ability to detect and monitor GEM  in
   the  environment.  It  has been  discovered  that  microorganisms  can
   undergo "dormancy" i.e., enter a viable but difficult or
   non-recoverable  stage. New techniques have been developed,  employing
   immunofluorescent/epifluorescent  microscopy,  coupled  with  5S  rRNA
   sequencing,  which allow accurate nongenetic detection of  GEM.  These
   techniques have been employed in aquatic systems.
                                 PAGE

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Connolly,  John  P., Mary E. Cleveland, and Parmely H.  Pritchard. In review.
Validity  of Partition Coefficient as the Adsorption Descriptor  in  Exposure
Concentrations Predictions: Studies with Kepone and Methyl  Parathion.  Water
Res.  (ERL,GB 415).

   This work investigates three major assumptions implicit in the use  of
   partition  coefficient as sole adsorption descriptor:  (1)  adsorption
   kinetics  are unimportant to fate and transport of the toxic  chemical
   because  they are rapid; (2) adsorption is a reversible  process;  and
    (3) equilibrium conditions are independent of the individual
   concentrations  of toxic chemical and adsorbing solid, depending  only
   on their ratio. Adsorption of Kepone and methyl parathion was found to
   be  rapid  and two-step, a fast adsorption for  approximately  5  min.
   followed by a slower adsorption to equilibrium at 1 to 2 hr.  Kinetics
   of  adsorption  indicated  adsorption  rate  was  controlled  by  mass
   transport  mechanisms.  Kinetics of methyl parathion  adsorption  were
   identical for sterile and biologically active systems to the point  of
   sterile  system equilibrium. Continued decrease of dissolved  14C  and
   total  mass recovery in the active system suggested degradation to  an
   irreversibly adsorbed compound. The results indicate that kinetics can
   be ignored for small particle size sediments but that reversibility of
   adsorption cannot be assumed. Equilibrium adsorption of both compounds
   at constant sediment concentration was described by a linear isotherm.
   Partition  coefficient was, however, an inverse function  of  sediment
   concentration, decreasing by as much as an order of magnitude  between
   sediment  concentrations  representative  of  suspended  sediment  and
   sediment  concentrations representaive of bed sediment.  Therefore,  a
   single partition coefficient is inadequate for exposure  concentration
   predictions.

Couch,  John A.  In press. Carcinogenicity Tests: Utilization of  Ectothermic
Organisms.  Presented at "Alternative Approaches to Toxicity Testing" held at
Battelle  Laboratories, Columbus, Ohio, November 11-13,  1986.  27p.  (ERL,GB
599*).

   Certain ectothermic species, particularly some teleost fishes,  reveal
   promise  as carcinogen assay organisms and as carcinogen sentinel  and
   indicator  species in the environment. Reptiles,  amphibians,  fishes,
   and bivalve mollusks have been studied in terms of their
   responsiveness  to  chemical carcinogen exposures; of  these  species,
   fishes  have  been studied in greatest detail in the  last  20  years.
   Seven to eight species of teleosts have been studied in enough  detail
   to  be recommended as laboratory carcinogen assay subjects. These  are
   the  rainbow  trout,  Mekaka, guppy, Rivulus  sp.,  Poeciliopsis  sp.,
   sheepshead  minnow  and the brown bullhead. Bivalve mollusks  such  as
   oysters  and clams should be studied further as possible* models.  Many
   different test systems have been developed for use of aquatic  species
   in carcinogen studies. Neoplasms have been induced in 12 to 14 tissues
   in different species of fishes. Between 50-60 chemical cx3mpounds  have
   been  tested in fishes for their carcinogenic potential. Though  these
   areas of research are relatively new, considerable data and
   information are available on metabolism, pathologic, and environmental
   effects of carcinogens in ectothermic animals.
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Couch, J.A., and L.A. Courtney.  In press. DENA-Induced  Hepatocarcinogenesis
in  the  Estuarine Sheepshead Minnow (Cyprinodon variegatus):  Neoplasms  and
Related Lesions with Comparisons to Mammalian Lesions.  J. Natl. Cancer Inst.
(ERL,GB 589*) .

   Groups  of estuarine sheepshead minnows (Cyprinodon  variegatus)  were
   exposed  to  50-60 mg/1 N-nitrosodiethylamine (DENA) for five  to  six
   weeks.  Exposure  was stopped and the fish were  then  transferred  to
   clean,  flowing  seawater.  Induced  liver  lesions  were  studied  in
   periodic  samples of fish taken during the next 67 weeks  of  holding.
   Most  of these lesions were compared to their counterpart  lesions  in
   the rat. Certain lesions such as hepatocellular carcinomas,
   cholangiolar carcinomas, spongiosis hepatis (SH), and
   cholangiofibrosis  in our fish have apparent similar cellular  origins
   and  morphogenesis  to  those lesions in rats, and  perhaps  in  other
   mammals. SH in the sheepshead minnow apparently arises from
   perisinusoidal  cells  and may be a neoplasm of this  cell  type.  The
   general similarity of response to DENA in sheepshead minnows and  rats
   suggests that this fish has promise as an assay subject for
   identifying  some  hepatocarcinogens, and as a sentinal  organism  for
   detecting hepatocarcincgens in contaminated coastal waters.

Couch, John A. In review. Enclosed Systems for Testing Microbial Pest Control
Agents.  U.S. Environmental Protection Agency, Environmental Research
Laboratory, Gulf Breeze, FL.  (ERL,GB X526*).

   This  report  stems  from a workshop held at  the  EPA,  Environmental
   Research Laboratory, Gulf Breeze, Florida on February 18 and 19, 1986.
   The  workshop  and  report were requested  by  the  Hazard  Evaluation
   Division  of the Office of Pesticide Programs. The report consists  of
   descriptions and documentation of some enclosed, multispecies  systems
   that may be used for laboratory testing of both natural and
   genetically  altered microbial pest control  agents  (MPCA's—viruses,
   bacteria,  fungi,  and  protozoa) for possible  effects  in  nontarget
   species, and ecosystems.
                                 PAGE  11

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Gripe,  Geraldine  M., David J. Hansen, Stephanie F.  Macauley,  and  Jerrold
Forester.  1986.  Effects of Diet Quantity on Sheepshead Minnows  (Cyprinodon
variegatus) During Early Life-Stage Exposures to  Chlorpyrifos.  In:  Aquatic
Toxicology  and Environraental Fate: Ninth Volume, ASTM STP 921.  T.M.  Poston
and R. Purdy, editors, American Society for Testing and Materials,
Philadelphia, PA.  pp. 450-460.  (ERL,GB 538).

   The  influence  of food quantity on the effects  of  chlorpyrifos  was
   determined  in  early life-stage (ELS) toxicity tests  with  estuarine
   sheepshead  minnows  (Cyprinodon variegatus). Three 28-day  ELS  tests
   were  conducted  simultaneously, each with a different  feeding  rate:
   approximately 20, 110 or 550 Artemia nauplii/fish per feeding. In  the
   first  group of three tests, growth was reduced significantly  (p  less
   than  or equal to 0.001) at nearly all feeding rates and  chlorpyrifos
   concentrations  tested  (3.1 to 52 ug/L). Therefore, a second group  of
   three tests was conducted at lower chlorpyrifos concentrations (0.4 to
   6.8  ug/L)  and  the  same feeding rates used  in  the  first  series.
   Chlorpyrifos  concentrations that significantly decreased fish  growth
   were  greater than or equal to 3.0 ug/L, regardless of  feeding  rate.
   Weights of fish at the end of all tests were directly associated  with
   concentration  and  food. Fish receiving the greatest amount  of  food
   weighed  10 times more than those receiving the least and  were  three
   times  heavier  than  those  in  the  intermediate  feeding  rate.  In
   treatments where growth was affected, mean percentage survival  ranged
   from  67% at 52 ug/L to 99% at 3.0 ug/L. The standard  deviations  for
   this  survival  varied  from 14 at the lowest feeding  rate  for  fish
   exposed to 52 u/L to 2.8 for fish fed 550 Artemia per cup in 3.0 ug/L.
   Bioconcentration factors (amount of chlorpyrifos in tissue divided  by
   average measured water concentrations) and chlorpyrifos in whole  fish
   at exposure concentrations greater than or equal to 3.0 ug/L generally
   increased  with  increasing feeding rates and  increased  chlorpyrifos
   concentrations.  Within  the  feeding range tested,  the  quantity  of
   available food was not an important factor controlling differences  in
   growth of Cyprinodon variegatus exposed to chlorpyrifos. However, when
   food  quantity restricted growth, survival of sheepshead.  minnows  was
   not  as reproducible, and variability  (standard  deviation)  increased
   with decreased food.
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Cripe, C.R., E.J. O'Neill, M.E. Woods, W.T. Gilliam, and P.H.  Pritchard.  In
review. Fate of  Fenthion in Salt-Marsh Environments:  1.  Factors  Affecting
Biotic  and  Abiotic  Degradation  Rates  in  Water  and  Sediment.  Environ.
Toxicol. Chem.   (ERL,GB 583*).

   Fenthion   (Baytex),  an  organophosphate  insecticide,  is  frequently
   applied to salt-marsh environments to control mosquitoes.  Shake-flask
   tests  were used to study rates of abiotic and biotic  degradation  of
   fenthion  and  the environmental parameters that affect  these  rates.
   Water  or  water-sediment   (500 mg dry weight/L)  slurries  from  salt
   marshes  located  along the Northwest Florida Gulf  Coast  were  used.
   Flasks  contained  200  ug  fenthion/L,  and  degradation  rates  were
   determined by following decrease of fenthion over time. Hydrolysis and
   biodegradation in water were relatively insignificant fate  processes;
   fenthion disappeared from flasks containing water, formalin-sterilized
   water, or formalin-sterilized sediment very slowly (half-life equal to
   or greater than 2 weeks). The presence of nonsterile sediment resulted
   in  a rapid exponential disappearance of fenthion (half-life equal  to
   or  greater than 3.8 days). Biodegradation was assumed  since  sterile
   sediment  systems showed a much slower decrease of fenthion,  and  the
   production of polar compounds (hexane-unextractable)  from radiolabeled
   fenthion  was  greater  in the presence of  sediment  than  sterilized
   sediment.

Cripe, Geraldine M.  In press. Occurrence of Mysidopsis bahia
(Mysidacea,Mysidae) on the Atlantic Coast of Florida.  Crustaceana  (Leiden).
2p.  (ERL,GB 560*).

   A  collection of mysids was taken from Link Port Channel, Ft.   Pierce,
   Florida  on  December  6, 1984,  at 20 salinity and 24  degrees  C  and
   returned  to  our  laboratory  for  culture  and  identification.   All
   twenty-two individuals were identified as Mysidopsis bahia: 15
   females,  4 males, and 2 juveniles (sex undetermined). Gravid  females
   averaged  7 mm length (base of eyestalk to posterior ends of  uropods,
   excluding  setae)  and had a mean brood of 5.4 young (range 2  to  10).
   Mature  males ranged from 6 to 7 mm length (mean 6.5 mm). A sample  of
   these  mysids was sent to Dr.  Thomas E. Bowman at the National  Museum
   of Natural History and identified as M. bahia.
                                 PAGE  13

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Gripe,  C.R.,  W.W.  Walker, P.H. Pritchard,  and  A.W.  Bourquin. In review.
Snake-Flask Test for Estimation of Biodegradability of Toxic Organic
Substances  in  the  Aquatic  Environment.  Ecotoxicol.  Environ.  Saf.  24p.
(ERL,GB 603*).

   Disadvantages  of current biodegradation tests are examined: the  need
   for high substrate concentrations, lack of parent compound
   concentration measurements, no estimation of sediment effects, failure
   to  indicate  compounds to which microbial populations must  adapt  to
   degrade and lack of site-specificity in innocula selection. A modified
   river  die-away test is proposed for determining  biodegradability  of
   organic compounds and testing for toxic degradation products. Our test
   uses shake flasks containing sterile (2% formalin) and nonsterile site
   water: both with, and without, site sediment (500 mg/liter).
   Concurrent  toxicity  testing  with  mysids  or  daphnids  provides  a
   sensitive  assay for the detection of toxic metabolites.  Examples  of
   three  test  compounds are given: methyl  parathion,  which  undergoes
   rapid,  sediment-mediated biodegradation; dibutylphthalate,  to  which
   some  microbial  communities  exhibit an  adaptation  phenomenon;  and
   methoxychlor,  which  has a relatively low water solubility  and  high
   sediment  partition  coefficient.  The relative merits  of  this  test
   procedure are discussed.

D'Asaro,  Charles N.  1986.  Egg Capsules of Eleven Marine Prosobranchs  from
Northwest Florida.  Bull. Mar. Sci.  39(1):76-91.   (ERL,GB X527*).
Avail, from NITS, Springfield, VA: PB87-169207.

   Egg  capsules  of eleven prosobranchs are described  and  illustrated,
   including  Strombus  alatus, Murex fulvescens,   Urosalpinx  perrugata,
   Favartia  cellulosa,  Eupleura  sulcidentata,  Calotrophon  ostrearum,
   Cantharus  cancellarius, C. multangulus, Fasciolaria lilium  hunteria,
   Conus floridanus floridensis, and C. jaspideus stearnsi.  Enumerations
   of  capsules  and  embryos,  and  capsular  dimensions,  developmental
   pattern, and observations on reproductive behavior are given.

D'Asaro,  Charles  N.  1986.  Laboratory  Spawning, Egg  Membranes,  and  Egg
Capsules  of 14 Small Marine Prosobranchs from Florida and  Bimini,  Bahamas.
Am. Malacol. Bull.  4(2):185-199.   (ERL,GB X533).
Avail, from NTIS, Springfield, VA: PB87-178729.

   Specific substrata or locations used for oviposition and external  and
   internal structure of egg capsules produced by small prosobranchs from
   seagrass  beds  and coastal splash pools are described.  Included  are
   Tricolia affinis affinis (C.B. Adams, 1850), T. thalassicola
   Robertson,  1958,  T. bella  (M. Smith, 1937),  Puperita  pupa   (Linne,
   1767), Smaragdia viridis viridemaris Maury, 1917, Littprina  mespillum
   (Muhlfeld, 1824), Alvania auberiana  (Orbigny, 1842), Rissoina
   catesbyana   (Orbigny,  1842),  R.  bryerea   (Montagu,  1803),  Zebrina
   browniana  (Orbigny,  1842), Rissoella caribaea Rehder,  1943,  Caecum
   nitidum  Stimpson,  1851, Marginella aureocincta  Stearns,  1872,  and
   Granulina ovuliformis (Orbigny, 1841).
                                 PAGE  14

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Davis,  William P.  1986.  Role of Rivulus marmoratus in Research on  Aquatic
Pollutants.  J. Am. Killifish Assoc.  19(1):70-80.  (ERL,GB 556).

   The  role of Rivulus marmoratus in research in  environmental  aquatic
   research  is described. The unique biology of R.  marmoratus  provides
   the aquatic toxicologist with the following advantages: 1. Ability  to
   thrive in small volume of water throughout life span; 2.  Reproduction
   through  internal  self-fertilization; 3. Isogenic clones  that  allow
   interclonal and specific intraclonal tissue transplants; 4.
   Reproductive  process  in  which  eggs are  laid  on  a  weekly  basis
   throughout the year; 5. Semiamphibious adaptations that contribute  to
   rapid uptake of waterborne and even some airborne compounds.

DeWeerd, Kim A., Joseph M. Suflita, Tim Linkfield, James M. Tiedje, and  P.H.
Pritchard. In review. Relationship Between Reductive Dehalogenation and Other
Aryl  Substituent Removal Reactions Catalyzed by Anaerobes.  FEMS (Fed.  Eur.
Microbiol. See.) Microbiol. Ecol.  42p.  (ERL,GB X529*).

   Anaerobic  bacteria are known to catalyze the removal of a variety  of
   aromatic  substituents  including  -COOH, -OH, -OCH3,  and  -CH3,  and
   halogens. We investigated whether reductive dehalogenation was related
   to other types of aryl substituent removal reactions. A dehalogenating
   bacterial  consortium was tested for its ability to use benzoic  acids
   substitute in the 3 position with the functional groups listed  above.
   In  addition  to  dehalogenation,  the  enrichment  (as  well  as  the
   dehalogenating  pure culture) was able to  transform  3-methoxybenzoic
   acid  to 3-hydroxybenzoic acid without a lag. This reaction  exhibited
   Michaelis-Menten  kinetics  with an apparent Km of 5 uM. To  test  the
   hypothesis  that  the  two  reactions were  related,  we  developed  a
   mathematical  model  incorporating a competitive  inhibition  term  to
   account  for the influence of one substrate on the degradation of  the
   other. However, experimental evidence showed no significant difference
   in the rates of 3-chlorobenzoic acid or 3-methoxybenzoic acid
   degradation in either the presence or absence of the other  substrate.
   The isolated dechlorinating organism strain DCB-1 was able to
   transform  3-methoxybenzoic acid in the presence of 1 mM  thiosulfate,
   but  the dehalogenation of 3-chlorobenzoic acid under such  conditions
   was  inhibited. Therefore, it is unlikely that a  relationship  exists
   between dehalogenation and other anaerobic aromatic substituent
   removal mechanisms.
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Diaz,  R.J., M. Luckenbach, S. Thornton, R.J. Livingston, C.C.  Kbenig,  G.L.
Ray,  and  L.E. Wolfe.  1987.  Field Validation of  Multi-Species  Laboratory
Test  Systems  for  Estuarine  Benthic  Communities.  EPA/600/3-87/016*f  U.S.
Environmental  Protection  Agency, Environmental  Research  Laboratory,  Gulf
Breeze, FL.  81p.

   The  major objective of this report was to determine the  validity  of
   losing  multi-species  laboratory systems to evaluate the  response  of
   estuarine  benthic  communities to an introduced stress. In  a  5-year
   period, experiments in Apalachicola Bay, Florida, and the York  River,
   Virginia  sought  to  (1)  develop criteria  for  microcosm  tests  to
   evaluate  the capacity of microcosms to model natural  communities  in
   the  presence and absence of pollution-induced stress and  (2)  assess
   the validity of extrapolating test results of one location to another.
   Individual  species  response patterns in the microcosms  were  highly
   variable and seldom showed good agreement with patterns in the  field.
   Species  richness  in  the  microcosms and  field  sites  showed  good
   temporal agreement and provided a conservative indicator of  community
   response  to a toxic stress. An ecologically based guild  approach  to
   grouping  species  proved  to be a powerful  and  reliable  method  of
   extrapolating  from  microcosm  test results  to  responses  of  field
   communities.

Duke,  T.W.,  and  P.R. Parrish. In press.  Drilling  Fluid  Test  Procedure:
Participation,  Data Comparison and Implementation.  Presented at  the  Ninth
Annual  Analytical Symposium Sponsored by EPA Office of Water Programs,  June
19-20, 1986, Norfolk, VA.  6p.  (ERL,GB 570*).

   The proposed Best Available Technology  (BAT) guidelines for  discharge
   of drilling fluids from off-shore oil and gas platforms require that a
   toxicity  test  be conducted on certain drilling  fluids.  This  paper
   describes participation of the Environmental Research Laboratory, Gulf
   Breeze,  in  evaluating the toxicity test methods and  conducting  the
   tests. Practical aspects  (availability of animals, suitable
   facilities,  effort required) of conducting such tests are.  discussed.
   Also,  interpretation  of the results of the tests with  reference  to
   biological variation and regulatory needs is presented.

Duke, Thomas W., and Donald I. Mount.  In press. Toxic Effects on
Individuals, Populations and Aquatic Ecosystems and Indicators of Exposure to
Chemicals.  Presented  at  the WHO Workshop on Methodologies for  the  Safety
Evaluation  of  Chemicals,  August 11-17, 1985,  Mexico  City,  Mexico.  21p.
(ERL,GB 550*) .
Avail, from NITS, Springfield, VA: PB85-237428

   This  paper  presents two research approaches  that  address  problems
   encountered in evaluating the effects of complex mixtures of chemicals
   on aquatic systems. The concept of ambient toxicity testing is applied
   to the impact of effluents in freshwater receiving waters (the concept
   also  applies to saltwater systems), where measurement of toxicity  is
   made  without  attempting  to identify the  toxics.  Another  approach
   develops  structural  and  functional  indices that  can  be  used  to
   evaluate impact of chemicals on communities maintained under
   controlled  conditions  in the laboratory. One approach  is  concerned
   with chemicals already in the environment; the other, with  developing
   ecosystem  level indices used to evaluate chemicals before they  reach
   the  environment.  Also, applicability of laboratory-derived  data  to
   field situations is discussed.


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Environmental  Research  Laboratory,  Gulf  Breeze,  FL.  1987.  Gulf  Breeze
Laboratory  Titles  and Abstracts: 1986, 1987, in Press  and  in  Review
Publications.  U.S.  Environmental Protection Agency, Environmental  Research
Laboratory, Gulf Breeze, FL.  79p.  (ERL,GB SR-104).

   This  report  represents an effort to provide  Agency  administrators,
   managers,  and  scientists  with the  most  timely  information  about
   availability  and  content  of the  Gulf  Breeze  Laboratory  research
   program.  Full  text, a report copy, or a reprint can be  provided  on
   request  to: Elizabeth Pinnell (904) 932-5311 or  (FTS) 686-9011.  This
   format is intended as a service to Agency users who may wish not  only
   to examine the title and abstract of a publication or report, but  who
   also have a need to know of the availability of technical
   documentation. To facilitate usage, publications are indexed by  title
   keywords and author.

Environmental  Research  Laboratory, Gulf  Breeze,  FL.  1986.  Publications:
Gulf Breeze Laboratory.  SR-107, U.S. Environmental Protection Agency,
Environmental Research Laboratory, Gulf Breeze, FL.  250p.  (ERL,GB  SR-107).

   This  report  lists  all published in-house  and  extramural  reports,
   publications and journal articles issued by the Environmental Research
   laboratory,  Gulf  Breeze, during the years 1970 through  the  present
   time.  It is divided into 3 sections:  standardized citations  grouped
   by  year of issue, a first author index, and a key-word  title  index.

Federle,  Thomas  W.,  Robert J. Livingston, Duane A. Meeter,   and  David  C.
White.  In press. Quantitative Comparison of Microbial Community Structure of
Estuarine Sediments from Microcosms and the Field.  Can. J.  Microbiol.  24p.
(ERL,GB X467*).

   Estuarine mud-flat sediments in microcosms and the field were compared
   with regard to microbial community structure. Community structure  was
   determined  by  analyzing the fatty acids derived from  the  microbial
   lipids  in  the sediments. Fatty acid profiles were compared  using  a
   multivariate  statistical approach. Experiments were  performed  using
   sediments  from  St. George Sound and Apalachicola Bay,  Florida.  The
   conmunity  structure of St. George Sound sediments was  controlled  by
   epibenthlc  predators.  In Apalachicola Bay, the  dominant  influences
   were  physical factors related to the flow of the Apalachicola  River.
   In  the  St.  George Sound experiment, microbial  communities  in  the
   microcosms differed from those in the field after only two weeks,  and
   the degree of this difference increased substantially as time
   progressed.  In  the Apalachicola Bay experiment,   although  microbial
   communities in the microcosms were detectably different from those  in
   the  field,  the degree of this difference was not large  nor  did  it
   increase with time. This differential behavior of sediment  communitie
   from  different  sites  may be related  to  the  different  ecological
   factors regulating ccramunity composition at these sites.
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Fisher, D.J., J.R. Clark, M.H. Roberts, Jr., J.P. Connolly, and L.H. Mueller.
1986.  Bioacxuraulation  of Kepone by Spot (Leiostomus xanthurus):  Importance
of Dietary Accumulation and Ingestion Rate.  Aquat. Toxicol.  9(2,3): 161-178.
(ERL,GB 580*) .

   The  relative extent of dietary accumulation and  bioconcentration  of
   Kepone by  spot  (Leiostomus xanthurus) was quantitatively evaluated  at
   food  rations  of  4,  8 or 20% of the average  wet  weight  of  fish.
   [14C]Kepone  was  utilized to determine bioconcentration  and  dietary
   accumulation  separately, while [14C]Kepone-contaminated  food   (grass
   shrimp, Palaemonetes pugio) and unlabeled Kepone in water were used to
   determine  simultaneously accumulation from both sources. Grass  shrimp
   and  spot  were exposed to the same aqueous Kepone concentration  (0.04
   ug/1). A first-order pharmacokinetic equation was used to model Kepone
   accumulation  kinetics during the 19-day uptake and  28-day  clearance
   phases.  A doubling of contaminated food ration caused a  doubling  of
   the  whole-body  Kepone concentration in spot. Spot fed 8%  ration  of
   uncontaminated food and exposed to aqueous Kepone did not
   bioconcentrate  significantly  greater amounts of the  pesticide  than
   fish fed 4% ration and exposed to the same aqueous concentration. When
   spot were  exposed to contaminated water and food, Kepone contributions
   from  each source  were additive. Feeding  rate,  however,  was  very
   important  in  determining  final Kepone body  burdens  in  spot.  The
   dietary  source of Kepone represented approximately 9, 18 and  37%  of
   the  total body burden bioaccumulated by fish fed 4, 8 and  20%  food
   rations,   respectively, but assimilation efficiencies of  Kepone  from
   the food source were low. The laboratory results further suggest  that
   dietary  accumulation of Kepone by spot may play an important role  in
   determining  final Kepone concentrations in spot in the  James  River,
   Virginia.

Fiercer,  David A., Virginia K. Tippie, Gail B. Mackiernan, Robert  B.  Biggs,
Willa  Nehlsen, and Kent S. Price.  In press. Characterizing  the  Chesapeake
Bay Ecosystem and Lessons Learned.  Presented at the Tenth National
Conference,   The  Coastal Society, New Orleans, IA, Oct.  12-15,  1986.  22p.
(ERL,GB 594*).
Avail, from NTTS, Springfield, VA: PB87-166930.

   During  the  scientific study phase, the U.S. Chesapeake  Bay  Program
   examined   the  complex ecological structure and processes of  the  Bay
   estuary  in  a coherent and manageable framework.  The  framework  was
   supported  by  a  rational spatial scaling or  segmentation,  with  an
   implicit   temporal scale. The historic geological, physical,  chemical
   (water  quality),  and  biological  data  were  analysed  within  this
   framework  to determine trends, correlations and,  where  appropriate,
   causal  relationships. The overall process resulted in a synthesis  or
   statement  on  the  environmental  condition  of  the  Chesapeake  Bay
   ecosystem.  We provide an explanation of the strengths and  weaknesses
   of  the  approach and suggest improvements in future efforts  of  this
   type.
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Fiercer, David A., Thomas W. Duke, and Foster L. Mayer, Jr.  1986.
Integration  of  Monitoring  and  Research  in  Coastal  Waters:  Issues  for
Consideration from a Regulatory Point of View.  In:  TKKF! Oceans '86
Conference Proceedings,  pp. 980-992.  (ERL,GB 581).

   Coastal  marine  ecosystems  are characterized by  a  high  degree  of
   natural  variability.  The weak resolving power of marine  science  to
   differentiate  between  effects ascribable to natural  factors  versus
   human  intervention often leads to unrealistic expectations of  "goods
   and services" that these ecosystems can provide. This high uncertainty
   often  contributes to faulty communication among scientists,  resource
   managers  and  the  public. We believe that this  problem  is  further
   enhanced by misunderstandings of the need to integrate monitoring  and
   research.  We explain why monitoring is a retrospective  activity  and
   the  principal  way it can become a prospective  activity  is  through
   hypothesis  framing, testing, and modeling. We describe the logic  that
   underpins a program designed to characterize the limits of
   applicability of extrapolation from laboratory data to the field. This
   interactive,  iterative  process couples concepts  of  monitoring  and
   research  so  that  the research question and  method  are  linked  to
   spatial  and temporal scales of ecological variability.  Without  such
   considerations, important ecological relationships remain unspecified,
   thus  precluding meaningful approaches to management of  such  complex
   but valuable ecosystems.

Foss, Steven S., Lee A. Courtney, and John A. Couch.  1986.  Evaluation of  a
Fungal  Agent  (Lagenidium  giganteum)  Under  Development  as  an  MPCA  for
Nontarget  Risk.  EPA/600/X-86/229,  U.S.  Environmental  Protection  Agency,
Environmental Research Laboratory, Gulf Breeze, FL.  12p.

   This  report  deals  with the development  of  methods  for  nontarget
   testing of fungal microbial pest control agents (MPCAs). The
   investigations of Lagenidium giganteum, a natural pathogen of mosquito
   larvae, a potential registrant as an MPCA, and our selected  prototype
   fungal agent, are presented and discussed. Methods for testing various
   life  stages of shrimp  (e.g., Palaemonetes pugio) and  embryonic  fish
   (e.g.,  Menidia beryllina) are outlined and evaluated. Also,  salinity
   tolerance testing of the freshwater fungus is summarized. The  methods
   presented  provide  relatively simple procedures  for  single  species
   testing  of aquatic fungi and incorporate a positive control assay  to
   confirm the infectivity of the MPCA at the time of testing. Results to
   date  indicate  the systems to be viable, inexpensive,  and  reliable.
   Preliminary  data suggest that the selected nontarget species are  not
   affected  by  L. giganteum. Future studies and refinements of  the  L.
   giganteum systems are under consideration. Additionally, a
   multispecies test system including plant and aniinal nontarget  species
   is  under  development.  Future  testing will  include  at  least  one
   additional  MPCA, a registered postemergent herbicide,  Colletotrichum
   gloeosporioides.
                                 PAGE  19

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Fredrickson,  H.,  and J. Refermat. In review. Microbial  14002  Release  and
Lipid Biosynthesis from Acetate, Lactate and Glucose in a Spartina
Rhizosphere  and a Nonvegetated Tidal Flat.  Appl. Environ.  Microbiol.  25p.
(ERL,GB 537*).

   The microbial biomass, community structure and coraraunity metabolism of
   sediment cores collected from the rhizosphere of Spartina alterniflora
   were  compared to those of an adjacent nonvegetated tidal flat.  Lipid
   cores injected with 14C-acetate, -lactate, -glucose or -p-cresol  were
   characterized  by column and thin layer chromatography, and  capillary
   gas-liquid chromatography/mass fragmentography. The rhizosphere
   contained  three  times  more lipid  (neutral  lipid,  glycolipid  and
   phospholipid) than the tidal flat sediment. The rhizosphere  contained
   more  b!5:0  and  less oleic acid than did  the  tidal  flat  sediment
   indicating a predominately anaerobic bacterial rhizosphere  cxammunity.
   [35S]-sulfate reduction rates were at least three times faster in  the
   rhizosphere. Acetate, glucose and p-cresol were mineralized faster  in
   rhizosphere  cores. lactate was mineralized four times faster and  14C
   from  lactate  was incorporated preferentially  into  glycolipids  and
   specific  neutral  lipids in the tidal flat cores.  This  study  shows
   microbial  biomass, community structure and community metabolism  were
   heterogeneous  within  sediments  less than 15  m  apart  and  benthic
   microbial communities showed substrate preferences for lipid
   biosynthesis.  The  catabolic  rate  of a  particular  compound  in  a
   sediinent is not necessarily directly related to:  (1) biomass,  (2)  the
   rate of catabolism of the compound in a different sediment or  (3)  the
   rate  of  catabolism  of a different compound in  the  same  sediment.

Gaetz,  Charles T., and Collard B. Sneed. In review. laboratory  Culture  and
Observations on the Reproductive Biology of the Marine Pelagic Isopod, Idotea
metallica (Crustacea; Isopoda).  Mar. Biol.   (ERL,GB 153*).

   Laboratory culture of the marine pelagic isopod, Idotea metallica,  is
   described.  I. metallica was reared through multiple  generations  and
   observations  were  made on its reproductive biology. These  data  are
   compared  with those obtained by others for this and related  species.
   Female I. metallica are capable of producing sequential broods in  the
   laboratory without passing through intervening non-reproductive
   intermolt  periods. Mean brood size is 33 and the mean period  between
   egg  fertilization  and juvenile release is 16 to 17  days.  Juveniles
   emerge  from the marsupium 1.5 to 2.0 mm in length and  begin  feeding
   immediately.  Sexual dimorphism is evident in 25 to 30 days  at  which
   time isopods are 6.0 To 7.5 mm in length. Sexual maturity is  attained
   when  isopods reach 10 to 12 mm, resulting in a generation time of  80
   to 85 days.
                                 PAGE  20

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 Gaetz,  Charles T., Richard Montgomery, and Thomas W.   Duke.   1986.   Toxicity
 of  Used  Drilling Fluids to Mysids  (Mysidopsis  bahia).   Environ.   Toxicol.
 Chem.  5(9):813-821.  (ERL,GB X392) .

    Static,  acute toxicity tests were conducted with  mysids  (Mysidopsis
    bahia)  and  11  used  drilling fluids  (also  called  drilling  muds)
    obtained from active drilling platforms in the Gulf of Mexico in  U.S.
    waters.  Each  whole mud was tested, along with three phases  of  each
    mud:  a liquid phase with particulate materials removed,  a  suspended
    particulate phase composed of soluble and lighter particulate
    fractions  and  a solid phase composed mainly of  drill  cuttings  and
    rapidly  settling  particulates. These muds represented seven  of  the
    eight generic mud types described by the U.S. Environmental Protection
    Agency  for  use  on  the  U.S.  Outer  Continental  Shelf.  Based  on
    volume:volume  preparations  of  the drilling muds  in  seawater,  the
    lowest 96-hour LC50s obtained were 26 ul/1 for whole mud,  11,400  ul/L
    for the liquid phase, 726 ul/L for the suspended particulate phase and
    1,456 ug/1 for the solid phase. The toxicity of the 11 muds tested was
    apparently increased by the presence of aliphatic components.

 Genthner, Fred J., Pramita Chatterjee, Tamar Barkay, and Al W.  Bourquin.   In
 review. Genetic Stability of Plasmid ENA in Aquatic Bacteria. Appl.   Environ.
 Microbiol.  20p.   (ERL,GB 595*).

    Sixty-nine  randomly  selected, gram  negative,  freshwater  bacterial
    isolates  were  screened  for their ability  to  receive  and  express
    plasmids  from  Pseudomonas aeruginosa donors, using  a  plate  mating
    technique. The plate mating technique identified 26 of the isolates as
    recipient-active  for the self-transmissible, wide host-range  plasmid
    R68,  14%  were recipient-active,  by RP4 mobilization,   for  the  wide
    host-range plasmid cloning vector R1162. Frequencies of transfer  were
    compared by using 3 conjugal transfer procedures: broth mating,  plate
    mating,  and  filter  mating.  With every  recipient  tested  a  solid
    environment  was  superior to liquid for transfer.   The  broth  mating
    technique failed to demonstrate R68 transfer in 63% of the
    recipient-active  isolates.  Filter mating, in  general,  yielded  the
    highest  transfer frequencies. The more rapid plate mating  procedure,
    however,  was  just as sensitive for testing the capacity  of  natural
    isolates to participate in conjugal plasmid transfer.

 Goodman, Larry R., Geraldine M. Gripe, Paul H. Moody,  and Darrel G.   Halsell.
In review. Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin
 Chloride  to  Mysids  (Mysidopsis  bahia)   of  Three  Different  Ages.  Arch.
 Environ. Contam. Toxicol.  17p.  (ERL,GB 598*).

    Mysids (Mysidopsis bahia)  of three ages (less than or equal to 1-, 5-,
    and 10-d-old at test initiation) were confined within the same aquaria
    and exposed to measured concentrations of malathion,
    tetrabromobisphenol-A,  and  tributyltin chloride  in  separate  96-hr
    acute toxicity tests. Sensitivities of the three age groups were  very
    similar.  Ninety-six hour LC50 values ranged from 2.6 to 3.1 ug/L  for
    malathion and from l.l to 2.2 ug/L for tributyltin chloride. The 96-hr
    LC50 for less than or equal to 1-d-old mysids exposed to
    tetrabromobisphenol-A was 86Q ug/L, and approximately 50% of the 5-and
    10-d-old mysids died at 1150 ug/L.
                                  PAGE  21

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Goodman,  Larry R., and Geraldine M. Gripe.  1987.  Cage for Use  with  Small
Aquatic Animals in Field Studies.  J. Am. Mbsq. Control Assoc.  3(1): 109-110.
(ERL,GB 579) .

   A cage was developed and used with small sheepshead minnows
   (Cyprinodon  variegatus)  and mysids (Mysidopsis bahia)  in  estuarine
   field  studies. The cages float on their sides and can be deployed  at
   the  water's  surface  or submerged at  various  depths.  Construction
   materials  are  noncorrosive,  relatively inert,  and  will  withstand
   cleaning with acetone and a mild bleach solution.

Grimes,  D.J.,  C.C. Somerville, W. Straube, D.B. Roszak,  B.A.  Ortiz-Conde,
M.T.  MacDonell, and R.R. Colwell. In review. Plasmid Mobility in  the  Ocean
Environment.  Presented  at  the  10th Symposium on  Aquatic  Toxicology  and
Hazard  Assessment,  ASTM,  New Orleans, LA,  May  4-6,  1986.  15p.  (ERL,GB
X523*).

   Evidence of plasmid selection and genetic exchange in natural  aquatic
   environments,  including  the ocean, includes:  (I) high  incidence  of
   plasmid  containing strains in polluted areas,  (II) presence  of  free
   ENA in natural environments,  (III) co-existence of identical  plasmids
   in  different co-habiting strains, and  (IV) data from in situ  plasmid
   transfer  experiments.  Current research in our  laboratory  regarding
   plasmid mobility in the ocean centers around viable but non-culturable
   bacteria, cloning of ecologically significant genes, genetic  exchange
   between  deep  sea  bacteria under pressure at  low  temperature,  and
   development  of  a 16S ribosomal ENA probe  for  tracking  genetically
   engineered  microorganisms that are released to natural  environments.

Grizzle,  John M.  1986.  Lesions in Fishes Captured near Drilling  Platforms
in  the Gulf of Mexico.  Mar. Environ. Res.  18(4):267-276.   (ERL,GB  X514*).

   Fish were collected near two actively drilling, petroleum-well
   platforms  and  from  control areas near the Flower  Garden  Banks,  a
   natural  reef  area in the northwestern Gulf of  Mexico.  Hepatomegaly
   (enlargement  of  the  liver) occurred in  gray  triggerfish  Balistes
   capriscus,  creole-fish Paranthias furcifer,  wenchman  Pristipomoides
   aquilonaris  and  southern  hake Urophycis  floridana  collected  near
   platforms.  Compared  with control fish,  creole-fish  and  vermillion
   snapper  Rhomboplites  aurorubens collected near  platforms  had  more
   frequent  gill  lesions. Southern hake from platform stations  had  an
   increased  prevalence  of  hepatic fatty change.  Pathogens  were  not
   observed in association with the lesions that were more common in fish
   collected  near platforms. The toxicants causing these lesions  cannot
   be  determined  from this study because the lesions  could  have  been
   caused by a wide variety of chemicals.
                                 PAGE  22

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Hansen,  David  J., Larry R. Goodman, Geraldine M. Gripe,  and  Stephanie  F.
Macauley.  1986.  Early  Life-Stage Toxicity Test Methods for  Gulf  Toadfish
(Opsanus  beta)  and Results Using Chlorpyrifos.  Ecotoxicol.  Environ.  Saf.
11:15-22.  (ERL,GB 549).

   Gulf toadfish (Opsanus beta) were continuously exposed as embryos, sac
   fry  and  juveniles  to technical chlorpyrifos  in  two  49-day  early
   life-stage  toxicity  tests. Survival was significantly   (a  =  0.05)
   reduced only in 150 ug/liter. However, toadfish exposed to
   chlorpyrifos concentrations from 3.7 to 150 ug/liter weighed
   significantly  less than control fish:  9% lower in 3.7  ug/liter  to
   62%  lower in 150 ug/liter. The 96-hr LC50 for juvenile fish  was  520
   ug/liter. Concentrations of chlorpyrifos in toadfish and
   bioconcentration factors increased with increasing exposure
   concentration,  a condition not generally observed with  other  marine
   fishes  and  other  test chemicals.  These  results  demonstrated  the
   procedures  for, and the practicality of, early life-stage tests  with
   this  marine  species. We recommend the use of the gulf  toadfish  for
   comparative  toxicity  testing  and for  evaluating  the  toxicity  of
   substances in conjunction with ontogenetical, physiological and
   histological investigations of this considerably studied genus. We  do
   not recommend it for routine effects testing.

Hinton, David E., John A. Couch, Swee J. Teh, and Lee A. Courtney. In review.
Cytological  Changes During Progression of Neoplasia.  Aguat.  Toxicol.  23p.
(ERL,GB X539*).

   Cytological changes during progression of hepatic neoplasia in  fishes
   were reviewed with emphasis on recent findings in Cyprinodon
   variegatus and Oryzias latipes. Hepatocytes are particularly sensitive
   to  toxic  changes  during early phases  of  response  to  carcinogens
   reflecting both lethal and sublethal alterations. Enzyme histochemical
   studies reveal marked deficiency of glucose-6-phosphate dehydrogenase,
   glucose-6-phosphatase and adenosine triphosphatase. Surviving
   hepatocytes are either enlarged, encircled by cells with small nuclear
   to cytoplasmic rations, and have altered nuclear morphology suggestive
   of  an  inability  to  divide, or,  are  smaller,  apparently  rapidly
   dividing, and have basophilic cytoplasm. In both species,  development
   of spongiosis hepatis occurred following cytotoxic phases. This lesion
   apparently  provides  abundant space for  cellular  remodeling  during
   neoplastic  progression leading to eventual multinodular change.  Foci
   of altered hepatocytes included basophilic, eosinophilic  (both
   species)  and clear cells (Cyprinodon variegatus only). Enzyme
   alterations  preceded other morphologic alterations and were  seen  in
   cells of foci and tumors suggesting lineage of phenotypic  alteration.
   Cytologic  changes  within  other  resident  cell  populations  during
   neoplastic progression were reviewed.
                                 PAGE  23

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Kelly,  John R., Thomas W. Duke, Mark A. Harwell, and Christine  C.  Harwell.
In review. Ecosystem  Perspective  on Potential  Impacts  of  Drilling  Fluid
Discharges on Seagrasses.  Environ. Manage.  52p.  (ERL,GB X528*).

   Potential  effects  of oil drilling fluid  discharges  upon  Thalassia
   seagrass  ecosystems were examined to provide general insights and  to
   raise  specific ecotoxicological issues concerning ecological  effects
   of  anthropogenic actions. Microcosm experiments demonstrated  effects
   upon both autotrophic and heterotrophic species, and the processes  of
   primary productivity and decomposition. Significant ecological changes
   may  result from disturbance effects related to the physical  presence
   of higher particle loads, in addition to effects from toxic
   constituents of drilling fluids. We argue that estimating effects upon
   both  ecosystem  processes  and  biotic  composition,  and  developing
   broader  ecological  understanding  of  the  particular  ecosystem  of
   concern, are required for environmental assessments seeking to provide
   a  scientific  basis for judging the  acceptability  of  environmental
   changes likely to ensue from human activities.

Klein,  Theodore  M., and Martin Alexander.  1986.  Bacterial  Inhibitors  in
Lake Water.  Appl. Environ. Microbiol.  52(1):114-118.  (ERL,GB X516).
Avail, from NTIS, Springfield, VA: PB87-152617.

   The  populations  of  six bacterial genera fell  rapidly  after  their
   addition to sterile lake water but not after their addition to buffer.
   The  decline  in  numbers of two species that  were  studied  further,
   KLebsiella  pneumoniae and Micrococcus flavus, occurred even when  the
   buffer  was  added  to  sterile  lake  water.  The  inhibition  of  K.
   pneumoniae  by substances in lake water varied with the season of  the
   year,  and  the  rate  and extent of  decline  of  both  species  were
   different  in  sterile  samples  of different  lakes.  The  extent  of
   reduction  in the density of K. pneumoniae was independent of  initial
   population size and was diminished by the addition of 10 ug of glucose
   per  ml  of  lake  water. The toxin was removed  from  lake  water  by
   dialysis  and by a cation-exchange resin but not by an  anion-exchange
   resin,  and  it  was  destroyed  by  heating.  The  inhibition  of  K.
   pneumoniae was not evident in lake water buffered at a pH value  above
   8.0.  We  suggest  that toxins may be  important  in  determining  the
   composition of the bacterial community of lakes.

Kokjohn, Tyler A., and Robert V. Miller. In review. Characterization of  recA
Mutants  of  Pseudomonas  aeruginosa:  rec-102 is  a  Mutant  Allele  of  the
Pseudomonas  aeruginosa PAD recA Gene.  J. Bacteriol.  32p.  (ERL,GB  X535*).

   Several  recombination  deficient  mutations  have  been  isolated  in
   Pseudomonas  aeruginosa PAO. None has been shown to be in a  recA-like
   function.  A  fragment  of  the P.  aeruginosa  PAO  chromosome  which
   complements Escherichia coli recA mutations was used to probe
   chromosomal digests of isogenic Reef and Rec- strains of P.
   aeruginosa. When strains containing the rec-102 allele (R. Fruh,  J.M.
   Watson, and D. Haas. Mol. Gen. Genet. 191:334-337, 1983) were compared
   to  rec-102+  strains,  a restriction  endonuclease  polymorphism  was
   observed  in DNA showing homology to the  recA-complement:Lng  plasmid.
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Kbkjohn,  Tyler A., and Robert V. Miller. In review. Qiaracterization of  the
Pseudomonas  aeruginosa PAO recA Analogue and Identification of  Its  Protein
Product.  J. Bacteriol.  36p.  (ERL,GB X534*).

   We  have  cloned  a  2.3 kilobase pair  fragment  of  the  Pseudomonas
   aeruginosa  PAO  chromosome  which is capable  of  complementing  recA
   mutations  of  Escherichia coli. The recA-complementing  activity  was
   further  localized to a 1.5 kilobase pair PvuII-Hindlll fragment.  The
   direction  of  transcription was determined. Southern  analysis  under
   conditions of high stringency indicated that DNA sequence homology  is
   shared  by the E. coli recA gene and the P. aeruginosa recA  analogue.
   The  cloned  recA analogue was shown to restore resistance  to  methyl
   methane-sulfonate,  nitrofurantoin and ultraviolet irradiation  to  E.
   coli recA mutants.

Lores, Emile M., James C. Moore, and Paul Moody.  1987.  Improved Silica  Gel
Cleanup Method for Organophosphorous Pesticides.  Chemosphere.
16(5):1065-1069.  (ERL,GB 571).

   Quantitative recovery of some organophosphorous pesticide residues has
   not been possible with existing silica gel-cleanup procedures. We have
   developed  a  modification that permits quantitative recovery  of  all
   organophosphorous  pesticides  tested, except those with  a  carbamate
   functional group. The method uses a 3.5 g silica gel column with a  1%
   acetic acid wash to condition the column prior to the addition of  the
   sample.  Percentage recovery and standard deviation of compounds  such
   as  phorate  and disulfoton are 96 (5.6) and 98  (1.0),  respectively.
   Recoveries  range  from  92  to 101%  for  the  11  compounds  tested.

MacDonell,  M.T.,  S.C.  Morris, B.A. Ortiz-Conde, C.J.  Pillidge,  and  R.R.
Colwell.  In  press.  Application  of  Ion-Exchange  High-Performance  Liquid
Chromatography  in  the  Purification  of  5S  rRNAs  Suitable  for  Sequence
Analysis.  J. Chromatogr.  6p.   (ERL,GB X520*).

   A  simple,  dependable size-exclusion or ion-exchange method  for  the
   liquid  dhromatographic  separation  of  tRNAs  and  5S  rRNA  is  not
   available. Indeed, the method of choice for purification of small  RNA
   species consists of electrophoretic separation on denaturing
   polyacrylamide gels. Methods for purifying small  oligoribonucleotides
   using either conventionally or thiol-soluble3 polyacrylamide gels are
   well  developed. In this paper we describe a rapid and  reliable  HPLC
   method for purifying of 5S rRNA from biological samples with
   sufficient  homogeneity  of the preparations  for  sequence  analysis.

MacDonell,  M.T.,  B.A. Ortiz-Conde, G.A. Last, and R.R.  Colwell. In review.
Distribution of Mutations in Gram Negative Eubacterial 5S rRNAs and
Significance for Sequence Analysis.  J.  Microbiol. Methods.  (ERL,GB  X519*).

   Alignments  of 72 5S rRNAs from Gram negative Eubacteria were used  to
   derive  a position-wise frequency distribution of mutations along  the
   5S rRNA molecule. These empirically derived, position-wise frequencies
   were  used as coefficients for preparation of difference matrices  and
   construction  of  evolutionary  trees. Significance  of  the  observed
   distribution  of  mutations  in the 5S rRNAs, prepared  for  the  Gram
   negettive eubacteria, as well as its relationship to secondary
   structure are discussed.
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Mayer,  Foster  L.,  Jr.  1986.  Acute  Toxicity  Handbook  of  Chemicals  to
Estuarine Organisms.  EPA/600/8-87/017, U.S. Environmental Protection Agency,
Environmental Research laboratory, Gulf Breeze, FL.  274p.

   All  acute  toxicity data developed by the Gulf  Breeze  Environmental
   Research Laboratory, U.S. Environmental Protection Agency, since  1961
   were  evaluated  for quality. A data base was  established  for  1,175
   tests  with 197 chemicals and 52 species of estuarine  organisms.  The
   chemicals  represent  all  major  groups of  pesticides,  as  well  as
   numerous  industrial and inorganic chemicals. The compilation of  data
   presented here is unique in that the research was conducted within one
   laboratory system by methods that, for the most part, were based on or
   were  the consensus methods in use today. It should serve as a  useful
   data  base for the many agencies and organizations concerned with  the
   impact of chemicals on estuarine and marine environments.

Mayer,  Foster  L., Jr., Kathleen S. Mayer, and  Mark  R.  Ellersieck.  1986.
Relation of Survival to Other Endpoints in Chronic Toxicity Tests with  Fish.
Environ. Toxicol. Chem.  5(8):737-748.  (ERL,GB 577).
Avail, from NITS, Springfield, VA: PB-87-171138.

   Hazard  assessment  of chemicals in aquatic  organisms  often  include
   chronic  toxicity testing. The evaluation of exposure duration and  of
   the  life stages tested according to standard test methods has led  to
   the development of shorter chronic toxicity tests. A similar
   evaluation of biological endpoints (i.e., survival, growth and
   reproduction)  could  result  in tests that are  more  economical.  We
   analyzed  endpoints  for  28 chemicals and seven fish  species  in  34
   chronic  toxicity studies. When all endpoints were compared,  survival
   was  equal to or more sensitive than all other endpoints 56 to 69%  of
   the time. Individual endpoints were more sensitive than survival 19 to
   61%  of  the  time, except for reproduction,  which  was;  always  more
   sensitive   (although  there were few observations).  The  no  observed
   effect  concentration  (NOEC) for growth could be predicted  from  the
   NOEC  for survival by using interendpoint correlations  (r =  0.949  to
   0.974). Ratios of NOECs for survival to those for all other  endpoints
   examined  were  5 or less in 93 to 96% of  the  comparisons  (specific
   endpoint comparisons ranged from 80 to 100%). The determination of the
   survival endpoint requires less time and money than does the
   determination  of  most other endpoints, and it appears  adequate  for
   hazard assessments in the initial stage of estimating chronic
   toxicity.  However, a factor of at least 0.2 should be aipplied to  the
   estimated  no-effect  concentrations  for survival  to  include  other
   potentially biologically significant effects at least 95% of the time.
   The factor of 0.2 is based on frequency analyses that resulted in  the
   NOECs for survival being 5 times or less than the NOECs for most other
   endpoints  about  95%  of  the  time.  Univariate  analyses,  however,
   indicated  a  range  of  0.13  to 0.22  for  the  factor.  A  thorough
   evaluation  of  other published studies that contain  endpoints  other
   than  survival  should be conducted to define the  appropriate  factor
   more accurately.
                                 PAGE  26

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McKenney,  Charles  L.,  Jr.  1986.  Critical  Responses  of  Populations  of
Crustacea  to  Toxicants.  EPA/600/M-86/004,  U.S.  Environmental  Protection
Agency/ Environmental Research Laboratory, Gulf Breeze, Fl.  8p.

   The  objective  of  the  research summarized  herein  was  to  provide
   information necessary to determine appropriate responses for assessing
   the  long-term effects of various classes of pesticides  on  estuarine
   crustacean populations. Dose-response relationships of pesticide
   toxicity  and  individual physiological functions  were  examined  and
   compared  for  various  life stages of  estuarine  mysids  (Mysidopsis
   bahia), grass shrimp  (Palaemonetes pugio), and mud crabs (Eurypanopeus
   depressus). Correlations between physiological dysfunction of discrete
   life stages and alterations in the ecological fitness of the
   population  should  aid  in the selection  of  sensitive,  rapid,  and
   inexpensive monitoring tools for predicting chronic effects of
   pesticides on pesticide-sensitive estuarine populations.

McKenney, Charles L., Jr.  1986.  Influence of the Organophosphate
Insecticide  Fenthion  on  Mysidopsis bahia Exposed During  a  Complete  Life
Cycle: I. Survival, Reproduction, and Age-Specific Growth.  Dis. Aquat.  Org.
1(2):131-139.  (ERL,GB552).
Avail, from NTTS, Springfield, VA: PB87-171104.

   Survival,  growth,  and various measures of  reproductive  performance
   were examined for an estuarine mysid, Mysidopsis bahia, throughout its
   life cycle during exposure to the organophosphate insecticide,
   fenthion  (0,0-dimethyl 0-[3-methyl-4-(methylthio) phenyl]
   phosphorothioate). Concentrations of fenthion responsible for
   lethality (300 ng reciprocal of 1) did not vary significantly  between
   that observed after 4 d exposure of newly released juvenile mysids and
   that produced with continuous exposure through maturation and
   production of young. Exposure of maturing juveniles to 166 ng fenthion
   reciprocal  of  1  postponed the onset of reproduction by  4  d.  Both
   individual  fecundity  of females and total population  production  of
   young were reduced by fenthion concentrations of 79 ng reciprocal of 1
   and higher. Suppression of mysid growth rates was evident after only 4
   d exposure of juvenile mysids to sublethal fenthion concentrations  of
   166 ng reciprocal of 1; a lower concentrations (79 ng reciprocal of 1)
   retarded  growth rates of the more rapidly growing advanced  juveniles
   after approximately 2 wk exposure. Reduced survival capacity, retarded
   growth rates, and diminished reproductive success of mysid populations
   with  chronic, low-level exposure to fenthion would result in  lowered
   production  rates  of an important prey  population  for  commercially
   important fish that utilize the estuary as a nursery.
                                 PAGE  27

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McKenney,  Charles L., Jr.  1986.  Methods for Determining the  Influence  of
Biochemical  Biological Control Agents on Metamorphosis of Marine  Crustacea.
EPA/600/X-86/234, U.S. Environmental Protection Agency, Environmental
Research Laboratory, Gulf Breeze, FL.  18p.

   A historical and rational basis for the use of biochemical  biological
   control  agents (EGAs) as insect growth regulators in the  control  of
   insect  pests  is presented. The various major types of EGAs  used  in
   this  capacity  are identified and their unique modes  of  action  are
   described.  Procedures required for testing the influence of the  most
   extensively  used  BCA  to date, a juvenile  hormone  analog,  on  the
   complete  larval development and metamorphosis of a marine  crustacean
   are  presented in detail. Results utilizing these procedures with  the
   registered  juvenile hormone analog, methoprene, are presented.  These
   results  are discussed in conjunction with previous studies with  this
   compound and their implications regarding appropriate testing
   procedures for other biochemical BCAs.

McKenney,  Charles L., Jr. In press.  Optimization of  Environmental  Factors
During  the  Life Cycle of Mysidopsis bahia.  U.S.  Environmental  Protection
Agency,  Environmental Research Laboratory, Gulf  Breeze,  FL.  14p.  (ERL,GB
X541*).

   When considering both survival capacity of Mysidopsis bahia through  a
   complete  life cycle and tiipe required for juvenile mysids  to  become
   reproductively  mature, salinity- temperature conditions of 20 o/oo  S
   and  25 degrees Celsius appear optimal for this estuarine  crustacean.
   Optimization  of  growth and reproduction in this species  requires  a
   feeding  density  of 2-3 Artemia nauplii per ml of  seawater.  For  M.
   bahia  this food density results in maximum growth, shortest  duration
   prior  to  initiation of reproduction, and maximum  young  production.

Middaugh,  Douglas P., Michael J. Hemmer, and Daniel E.  Penttila. In review.
Embryo  Ecology  of  the Pacific Surf  Smelt,  Hypomesus  pretiosus  (Pisces:
Osmeridae).  Pac. Sci.  22p.   (ERL,GB 557*).

   A  study  of  the ecology of developing embryos of  the  Pacific  surf
   smelt, Hypomesus pretiosus, was conducted. Embryos were maintained  in
   the  laboratory  at  7.6,  12.1 and 17.6 degrees C  and  the  time  to
   specific  embryonic stages determined. Embryos held at 7.6  degrees  C
   developed  to stage 24, 18 days after collection; those held  at  12.1
   degrees  C hatched after 13 days; at 17.6 degrees C hatching  occurred
   8.5  days  after collection. Embryos maintained at 15  degrees  C  and
   salinities of 20, 25 and 30 salinity averaged 84% survival. There  was
   no  significant difference in survival between the groups  (ANOVA, p  =
   0.53).  Field  observations  indicated that  embryos  are  spawned  in
   patches in the upper intertidal zone near the time of high tide.  'They
   are  attached to gravel substrates by the zona radiata membrane  which
   ruptures  and  quickly  turns  inside out  at  the  time  embryos  are
   fertilized. After several days of development, stage 18 to 22  embryos
   detach  from the original spawning substrates and are  washed  seaward
   and  down into the gravel substrate in the intertidal  zone.  However,
   there was no significant difference (ANOVA, p is greater than or equal
   to 0.09) in the number of eggs found at each of 4 depth strata in  the
   upper, middle and lower intertidal zones.
                                 PAGE  28

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Middaugh,  D.P.,  and  M.J. Hammer.  In  press.  Influence  of  Environmental
Temperature  on Sex-ratios in the Tidewater Silverside,  Menidia  peninsulae.
Copeia.   (ERL,GB 568*).

   The  sex-ratios of Menidia peninsulae from Santa Rosa Island,  Florida
   were  studied  during  a  13 month  survey.  Weekly  samples  revealed
   significant  deviations  from the expected sex-ratio  of  1:1.  IXuring
   May-October,  young-of-the-year  (YOY) females comprised 70 to  94%  of
   the individuals collected in the 32.5 to 62.4 mm SL size class.  These
   females  are  the presumptive progeny of reproduction during  cold  to
   cool fluctuating temperatures, 15.5 to 22.5 degrees C, during
   February-April. In contrast, collections of YOY Menidia during
   November-April  yielded 34 to 60% females. These individuals  are  the
   presumptive progeny of reproductive activity and sexual
   differentiation in May-August at warm fluctuating temperatures of 25.0
   to  29.0 degrees C. The pattern  in sex-ratios of older Menidia 62.5  -
   102.4 mm SL paralleled that of YOY individuals. The annual  (13  month)
   sex-ratio  for collections of YOY and older Menidia was  identical  at
   68% females.

Middaugh,  Douglas  P.,  Michael J. Hemmer,  and  Yara  Lamadrid-Rose.  1986.
Laboratory  Spawning  Cues in Menidia beryllina and  M.  peninsulae  (Pisces,
Atherinidae)  with  Notes  on  Survival and Growth  of  larvae  at  Different
Salinities.  Environ. Biol. Fishes.  15(2):107-117.  (ERL, GB 508).
Avail, from NTTS, Springfield, VA:  PB86-208543.

   Spawning  patterns  of  inland   silversides,  Menidia  beryllina,  and
   tidewater  silversides,  Menidia peninsulae,  were  examined  in  the
   laboratory under several combinations of 'tidal1 and diel light  cycle
   cues. M. beryllina showed a high frequency of spawning throughout  the
   day  when held under constant conditions (24L: OD, current velocity  8
   cm sec-1) and when  'tidal' and diel light cycles were presented singly
   or  in  combination. In contrast, M. peninsulae  demonstrated  a  high
   frequency of spawning only when presented a combination of 'tidal1 and
   diel  light  cycle cues and spawned predominantly  at  night.  Menidia
   beryllina  embryos were euryhaline. Hatching ranged from 73 to 78%  at
   salinities  of  5, 15 and 30 0/00. M. peninsulae  embroyos  showed  an
   inverse  relationship between the percentage hatch and the  incubation
   salinity,  90% at 5 0/00 and only 65% at 30 0/00. Survival and  growth
   of  larval M. beryllina from the day of hatching through 16  days  old
   was optimal at 15 0/00. Although survival of M. peninsulae larvae  was
   optimal at 30 0/00, no trend was apparent in growth of larvae held for
   16 days at 5, 15, or 30 0/00 salinity.

Middaugh,  Douglas  P.,  Michael  J. Hemmer,  and  Larry  R.  Goodman.  1987.
Methods for Spawning, Culturing and Conducting Toxicity Tests with Early Life
Stages of Atherinid Fishes.  EPA/600/8-87/004*, U.S. Environmental  Protection
Agency, Environmental Research Laboratory, Gulf Breeze, FL.  56p.
Avail, from NTTS, Springfield, VA: PB87-174934.

   Procedures are presented for spawning, culturing and conducting  acute
   and  chronic  toxicity tests with four atherinid  fishes:  the  inland
   silverside, Menidia beryllina, Atlantic silverside,  M. menidia,
   tidewater silverside, M. peninsulae, and California grunion,
   Leuresthes  tenuis. Guidelines also are provided for growing  of  food
   organisns (Chlorella sp., Brachionus plicatilis, and Artemia sp.) that
   are  required  for  successful culture and testing  of  the  atherinid
   fishes.


                                 PAGE  29

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Middaugh, Douglas P., and Michael J. Hammer.  In press. Reproductive  Ecology
of  the Tidewater Silverside, Menidia peninsulae (Pisces:  Atherinidae)  from
Santa Rosa Island, Florida.  Copeia.  26p.  (ERL,GB 561*).

   The reproductive ecology of the tidewater silverside, Menidia
   peninsulae,  was  studied during February 1982 through  February  1983
   along the shoreline of Santa Rosa Island, Florida. Adult Menidia  were
   observed  at  low tide spawning on a red  alga,  Ceramium  byssoideum,
   which was growing in the cracks and crevices of a rocky substrate just
   below  the  low  tide line. Pinfish, Lagodon  rhoitiboides,  were  noted
   preying upon newly spawned Menidia eggs; gut analyses revealed a  mean
   number  of 191 eggs in five of the predators. The annual  reproductive
   cycle of Menidia extends from February through July or August with the
   highest spawning activity during March through June at water
   temperatures of 16.7 to 30.8 degrees C. A single female with ripe  ova
   was  collected  in  November. On eight  occasions,  minima  in  female
   gonadal  indices  occurred in association with recurring 3-  to  4-day
   periods of tropic tides, suggesting a tidally mediated spawning  cycle
   attuned  to  periods of very low tidal amplitude and  thus  low  tidal
   current velocities. Analysis of young-of-the-year Menidia (6-28 mm SL)
   revealed several distinct length classes indicating that spawning  and
   subsequent  hatching of larvae occurred in periodic pulses  throughout
   the spring and early summer.

Morton,  R.  Dana,  T.W. Duke, J.M Macauley, J.R.  Clark,  W.A.  Price,  S.J.
Hendricks, S.L. Owsley-Montgomery, and G.R. Plaia.  1986.  Impact of Drilling
Fluids  on  Seagrasses: An Experimental  Community  Approach.  In:  Community
Toxicity  Testing, ASTM STP 920.  John Cairns, Jr., editor, American  Society
for Testing and Materials, Philadelphia, PA.  pp. 199-212.   (ERL,GB 546).
Avail, from NITS, Springfield, VA: PB87-166807.

   Effects of a used drilling fluid on an experimental seagrass cxjrromanity
   (Thalassia  testudinum  Kbnig et Sims) were measured by  exposing  the
   community  to  the  suspended particulate phase  (SPP)  in  laboratory
   microcosms. Structure of the macroinvertebrate assemblage, growth  and
   chlorophyll  content of grass and associated epiphytes,  and  rates  of
   decomposition  as indicated by weight loss of grass leaves in  treated
   and  untreated  microcosms  were compared. Health of  the  plants  and
   structure  of  the  macroinvertebrate  assemblage  maintained  in  the
   laboratory were compared periodically with the seagrass community from
   which the plants and attendant sediment were taken. Treated microcosms
   were exposed to either 190 parts per million (ppm), volume to  volume,
   of  SPP  or an equivalent amount of  montmorillonite  clay.  Untreated
   microcosms received only flowing water from Santa Rosa Sound.  Sixteen
   replicates  were  provided for each treated and untreated  set.  There
   were statistically significant differences in community structure  and
   function  among untreated microcosms and those receiving the clay  and
   drilling  fluid.  For  example,  drilling  fluid  and  clay  caused  a
   significant  decrease  in  the numbers of  the  ten  most  numerically
   abundant   (dominant) macroinvertebrates, and drilling fluid  decreased
   the rate at which Thalassia leaves decomposed.
                                 PAGE  30

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Nelson, M.J., P.H. Pritchard, and A.W. Bourquin.  1986.  Aerobic
Biodegradation  of  Trichloroethylene.  U.S.  Department of  the  Air  Force,
Engineering  and Science Center, Tyndall Air Force  Base,  FL.  36p.  (ERL,GB
600*).

   Samples,  suspected of having a capability to  biologically  transform
   trichloroethylene  (TCE), were provided by Tyndall Air Force Base  for
   verification and characterization of activity. Biological
   transformation  of TCE was not observed in these samples.  Other  soil
   and  water samples, obtained from the Pensacola area,  were  therefore
   screened  for TCE degradation activity. One sample was found  to  have
   this  ability  and  a gram-negative bacillus,  which  appeared  to  be
   responsible  for  the metabolic activity was  isolated.  The  isolated
   organism  degrades TCE  (up to 3.4 uM) to less than 0.02 uM  within  24
   hours. TCE degradation occured only when water from the original  site
   of isolation and 02 were in the medium. The isolate converted TCE into
   002  and  unidentified nonvolatile products. Phenol,  toluene  0-  and
   m-cresol  were  found to replace the site water  requirement  for  TCE
   metabolism.

Nelson,  Michael  J.K., S.O. Montgomery, E.J. O'Neill,  and  P.H.  Pritchard.
1986.  Aerobic Metabolism of Trichloroethylene by a Bacterial Isolate.  Appl.
Environ. Microbiol.  52(2):383-384.   (ERL,GB 572) .
Avail, from NITS, Springfield, VA: PB87-152609.

   A  number of soil and water samples were screened for  the  biological
   capacity  to metabolize trichloroethylene. One water sample was  found
   to  contain this capacity, and a gram-negative,  rod-shaped  bacterium
   which  appeared  to  be responsible for  the  metabolic  activity  was
   isolated  from this sample. The isolate degraded trichloroethylene  to
   C02 and unidentified, nonvolatile products. Oxygen and water from  the
   original site of isolation were required for degradation.

Nelson,  Michael  J.K., Stacy 0. Montgomery, William R.  Mahaffey,  and  P.H.
Pritchard.  1987.  Biodegradation of Trichloroethylene and the Involvement of
an Aromatic Biodegradative Pathway.  Appl. Environ. Microbiol.
53(5):949-954.   (ERL,GB 593*).

   Biodegradation  of  trichloroethylene  (TCE) by the  bacterial  isolate
   strain  G4  resulted  in complete dechlorination of  the  compound  as
   indicated by the production of inorganic chloride. A component of  the
   water  from  which strain G4 was isolated that was  required  for  TCE
   degradation  was identified as phenol. Strain G4 degraded TCE  in  the
   presence of chloramphenicol only when preinduced with phenol. Toluene,
   o-cresol and m-cresol could replace the phenol requirement. Two of the
   inducers of TCE metabolism, phenol and toluene, apparently induced the
   same  aromatic degradative pathway that cleaved the aromatic  ring  by
   meta-fission. Cells induced with either phenol or toluene had  similar
   oxidation rates for several aromatic compounds and had similar  levels
   of catechol-2,3-dioxygenase. The results indicate one or more  enzymes
   of  an  inducible pathway for aromatic degradation in  strain  G4  are
   responsible for the degradation of TCE.
                                 PAGE  31

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Novidc,  Norman J., Reba Mukherjee, and Martin  Alexander.  1986.  Metabolism
of Alachlor and Propachlor in Suspensions of Pretreated Soils and in  Samples
from  Ground Water Aquifers.  J. Agric.  Food  Chem.  34(4):721-725.  (ERL,GB
X530*).

   Suspensions of soils treated in the field with alachlor
   [2-chloro-2', 6' -diethyl-N- (methoxymethyl) acetanilide]  and  propachlor
   (2-chlor-N-isopropylacetanilide)  were  tested for  their  ability  to
   metabolize these herbicides. Less than 8% of 14C ring-labeled alachlor
   was  mineralized in 30 days at concentrations of 10 and  0.073  ug/mL.
   The  soil suspensions mineralized 16-61% and 0.6-63%  of  ring-labeled
   propachlor  in  30  days at concentrations of 0.025 and  10  ug/mL  of
   suspension, respectively. Although soils converted alachlor to organic
   products, microorganisms able to mineralize the pesticide could not be
   isolated. Samples from ground water aquifers mineralized less than  1%
   of  the  herbicides  at the lower  concentrations,  but  four  organic
   products  were  formed  from  alachlor.  A  mixture  of  two  bacteria
   mineralized  57.6% of ring-labeled propachlor in 52.5 h. A product  of
   the microbial metabolism of propachlor was identified as
   N-isopropylaniline.  These findings suggest that mineralization  is  a
   major means for the destruction of propachlor but not for alachlor  in
   soil.

O'Brien,  Mark,  and  Rita R. Colwell. In review.  Rapid  Indirect  Test  for
Chitinase Activity Using 4-Methyluii±5elliferyl-N-Acetyl-B-I>K31ucxjsaminide.
Appl. Environ. Microbiol.  lip.  (ERL,GB X522*).

   One  hundred  and  one  strains of  bacteria  from  environmental  and
   clinical  sources, most of which were Gram negative, were  tested  for
   N-ac»tyl-B-I>^luc»saminidase  activity using a filter paper spot  test
   with 4-methylinnbelliferyl-N-a<^tyl-B-I>^lu
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Ogram, Andrew, Gary S. Sayler, Denise Gustin,  and Russell L.  Lewis.  In review.
DNA Sorption to Soils and Sediments.  Environ. Sci.  & Technol.   14p.  (ERL,GB
X540*).

   Deoxyribonucleic  acid (ENA) adsorption of five soils, an  acid-washed
   sand, and a lake sediment was investigated. All ENA at environmentally
   relevant concentrations was adsorbed by soils containing a significant
   amount of montmorillonite at low to neutral pH values. Studies on  the
   effects  of ENA molecular size on adsorption to sand and a sandy  soil
   were  described  by  the Freundlich isotherm  model  (r2  >0.85),  and
   revealed that the higher the molecular weight, the more the
   adsorption. The effects of ionic strength  (as sodium phosphate buffer)
   on  adsorption showed that adsorption decreases as  [P04=]  increases.
   Organic  carbon  was  found to play a relatively  minor  role  in  the
   adsorption  of ENA to these soils. A scheme for the extraction of  ENA
   from soils was also developed.

Parrish,  P.R., K.L. Dickson, J.L. Hamelink, R.A. Kimerle, D.J.  Macek,  F.L.
Mayer,  Jr.,  and  D.I. Mount.  In press. Aquatic Toxicology:  Ten  Years  in
Review  and  a  Look  at the Future.  Presented  at  the  Tenth  Annual  ASTM
Symposium  on  Aquatic Toxicology and Hazard Assessment, May 4-6,  1986,  New
Orleans, IA.  30p.  (ERL,GB X393*).

   This  Symposium marks the tenth time that we have gathered as a  group
   of professional scientists who share common goals and ideas concerning
   the protection of our Nation's aquatic resources. This 10th  Symposium
   seems  like a fitting time to reflect on our origins,  our  successes,
   and  cur  plans for the future. To that end, several people  who  have
   been  instrumental  in shaping the science of aquatic  toxicology  and
   hazard  (risk) assessment were invited to present their views  on  the
   growth  of this science and their ideas about its future.   This  paper
   is,  then,  a collection of those view points which are  set  down  in
   writing so that others may benefit from the experience of the  authors
   and  so that newcomers to this field may benefit by knowing about  the
   roots  of aquatic toxicology and hazard assessment. The fact that  the
   science  has persisted and grown over the past ten years is a  tribute
   to  all those who have contributed their time, energy, and  intellect.
                                 PAGE  33

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Parrish,  Patrick  R.,  and Thomas W. Duke.  In press.  Effects  of  Drilling
Fluids on Marine Organisms.  In:  Proceedings:  5th International Ocean
Disposal  Symposium.  Robert  Krieger Publishing  Co.,  Melbourne,  FL.  43p.
(ERL,GB 507*).

   Drilling fluids, also called drilling muds,  are essential to  drilling
   processes  in the exploration and production of oil and gas  from  the
   U.S. Outer Continental Shelf (CCS). These fluids are usually
   discharged from drilling platforms into surrounding waters of the  CCS
   and  are regulated by the U.S.  Environmental Protection Agency  (EPA).
   In a program carried out by the EPA Environmental Research  laboratory
   at Gulf Breeze, Florida, diverse marine species, as well as
   microbiotic and macrobiotic communities, were studied. Drilling fluids
   were toxic to marine organisms in certain concentrations and  exposure
   regimes. Furthermore, the fluids adversely affected benthos physically
   by burying them or by altering substrates. Toxicity of drilling  fluid
   components, used drilling fluids from active Gulf of Mexico sites, and
   laboratory-prepared drilling fluids varied considerably. For  example,
   96-h LCSOs were from 25 ul/1-1 to greater than 1,500 ul/1-1 for clams,
   larval lobsters, mysids, and grass shrimp. In most instances,
   mortality  was significantly (a = 0.05) correlated with  "diesel"  oil
   content  of  the fluids collected from the Gulf of  Mexico.  Data  and
   model  simulations suggest rapid dilution of drilling fliaids  released
   into  CCS waters, resulting in concentrations below the  acute  effect
   concentration  for  water  column organisms  tested.  Accumulation  of
   fluids  and cuttings on the bottom within a few hundred meters of  the
   discharge  could adversely affect benthic organisms. There is  concern
   that the potential hazard of drilling fluids may be underestimated  in
   some  instances because results of short-term toxicity tests  may  not
   reveal  subtle  effects  that could occur at the  ecosystem  level  of
   biological complexity.

Parrish, P.R., and T.W. Duke.  In press. Variability of the Acute Toxicity of
Drilling  Fluids  to  Mysids  (Mysidopsis  bahia).  In:  Proceedings  of  the
Symposium  on Chemical and Biological Characterization of Municipal  Sludges,
Sediments,  Dredge Spoils, and Drilling Muds.  American Society  for  Testing
and Materials, Philadelphia, PA.  15p.  (ERL,GB 596*).

   Numerous  factors  affect  the variability of the  acute  toxicity  of
   drilling fluids (muds) to mysids (Mysidopsis bahia). Source,
   composition,  and  age of drilling fluid sample; preparation  of  test
   material;  condition of test animals; and skill and experience of  the
   people conducting the tests can influence test results. Despite  these
   confounding  factors, our intralaboratory variation of  median  lethal
   concentrations  (96-h LCSOs)  for six tests with a  laboratory-prepared
   generic  drilling  fluid was within a factor of  two;  interlaboratory
   variation  for  seven  commercial laboratories that  tested  the  same
   generic  drilling  fluid  was within a factor of  four,  'the  same  as
   reported  in  the  literature for acute  toxicity  tests  with  single
   chemicals.  The presence of petroleum hydrocarbons in drilling  fluids
   greatly increases toxicity and, because toxic, volatile fractions  may
   be lost, variability of results from tests with petroleum
   hydrocarbon-contaminated  drilling  fluids may be  greater  than  that
   stated above.
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Pettigrew,  Charles  A., and Gary S. Sayler.  1986.  Use  of  DNA:ENA  Colony
Hybridization in the Rapid Isolation of 4-Chlorobiphenyl Degradative
Bacterial  Phenotypes.  J. Mcrobiol.  Methods.  5:205-213.  (ERL,GB  X525*).

   DNA:ENA  colony hybridization techniques were vised to select  isolates
   from  freshwater  sediment samples that contain  genes  homologous  to
   plasmid  pSS50,  coding for 4-chlorobiphenyl  biodegradation.  A  high
   degree of resolution was achieved in which target organisms
   representing  0.3% of the total population were discerned.  Initially,
   eight  positive cultures were obtained, these were found to  exist  as
   consortia  populations. Pure cultures, from the consortia,  were  then
   isolated  and  screened  for  4-chlorobiphenyl  degradatiye  genes  by
   DNA:DNA  colony  hybridization.  Each  strain  demonstrating  positive
   hybridization was subsequently shown to biodegrade 4-chlorobiphenyl to
   4-chlorobenzoate.  Following phenotypic characterization of  the  pure
   cultures  it was found that three different organisms were  repeatedly
   isolated  from  the various consortia populations. Field  sampling  to
   isolation  of  positive strains was accomplished within one  week  and
   completely avoided primary enrichment cultivation.

Price,  W.  Allen, John M. Macauley, and James R.  Clark.  1986.  Effects  of
Drilling  Fluids on Thalassia testudinum and Its  Epiphytic  Algae.  Environ.
Exp. Bot.  26(4):321-330.  (ERL,GB 555).
Avail, from NTIS, Springfield, VA: PB87-178661.

   A flow-through microcosm system was developed to assess the  potential
   influence of drilling fluids on Thalassia testudinium and its
   epiphytic algae. Two treatments  (drilling fluid and a  montmorillonite
   clay)  and a control were used for seven tests: two 10-day,  200  ul/1
   exposures;  two  10-day,  1000 ul/1; and  three  six-^week,  190  ul/1.
   Six-^week exposure to drilling fluid reduced epiphyte biomass (measured
   as  ash  free  dry weight/cm2), but surviving  algae  did  not  differ
    (measured  as  chlorophyll  a/g epiphyte ash  free  dry  weight)  from
   controls.  Thalassia productivity (carbon uptake and growth rate)  was
   reduced  by  10-day exposure to drilling fluid concentrations  of  200
   ul/1  and  1000 ul/1. Thalassia productivity was reduced  by  drilling
   fluid exposure in summer and fall but not in spring. The variation  in
   response is attributed to seasonal changes in Thalassia allotment  and
   storage of carbohydrates. The effect of montmorillonite clay  exposure
   varied inconsistently among all tests for both Thalassia and
   epiphytes.

Pritchard, p.H. In review. Assessing the Biodegradation of Sediment
Associated Chemicals.  In:  Workshop Proceedings: Toxicity and Fate of
Chemicals in Sediments.  49p.  (ERL,GB 530*).
Avail, from NTIS, Springfield, VA: PB86-11657/AS.

   Investigations  of  the  fate of xenobiotic  chemicals  in  laboratory
   systems  that  accommodate  the microbial  ecology  of  sediments  are
   described. These systems permit examination of biochemical  activities
   in  the  sediment bed with particular emphasis at  the  sediment-water
   interface.  Sediment may contain thousands of  microcxanmunities,  each
   containing  the  same  genotypic array of  metabolic  potential.  Each
   community,  however,  will demonstrate, depending on  the  surrounding
   conditions,  a  certain  phenotypic response  that  reflects  a  small
   portion of its total metabolic potential.
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Pritchard, P.H. , C.R. Gripe, W.W. Walker, J.C.  Spain,  and A.W.   Bourquin.   In
press. Biotic and Abiotic Degradation Rates of Methyl  Parathion in Freshwater
and Estuarine Water and Sediment Samples.  Chemosphere.   (ERL,GB 513) .

   Statistical analysis of degradation rates of methyl parathion  samples
   from two Gulf Coast estuaries over a three-year period indicated  that
   biodegradation occurred in the presence of sediment but was
   insignificant in water. Sediment rates always showed the same relative
   five-fold  difference  at a primary site within each  estuarine  area.
   Samples  from  11 ancillary sites indicated  biodegradation  rates  in
   sediments can be subdivided into two groupings which were  independent
   of seasonal differences (excluding temperature) . Spatial variations in
   rates, therefore, may be of minor environmental significance for  this
   chemical in estuarine areas.

Pritchard, P.H. , L.H. Mueller, J.C. Spain, and A.W. Bourquin.  1986.
Degradation of Jet and Missile Fuels by Aquatic Microbial  (jommunities.  U.S.
Air Force, Tyndall AFB, Panama City, FL.  177p.   (ERL,GB 590*) .

   The  fate  of  jet  fuel   (JP-4)  in  aquatic  sediments  was  studied
   concomitantly  in laboratory test systems and in the field.   Sediments
   from an estuarine pond were dosed with jet fuel and then reapplied  to
   the  pond  as well as into plexiglass trays on the  sediment  bed  and
   quiescent  bottle  tests  in  the  laboratory.  Thirty-three  selected
   hydrocarbons  in the jet fuel were followed chemically  to  quantitate
   relative hydrocarbon losses. Several hydrocarbons which biodegraded or
   rapidly volatilized in the bottle tests were much slower to  disappear
   in  the field and the plexiglass trays. In general, mixing of the  jet
   fuel  with  sediments  increased the  persistence  of  the  associated
   hydrocarbons.  The high density missile fuels RJ-5 and  JP-9  resisted
   biodegradation when incubated with water/sediment suspensions
   collected  from aquatic habitats. RJ-5 and JP-9 were not toxic to  the
   microbial communities at concentrations of 400 mg per liter, but  RJ-5
   was  toxic to Mysidopsis bahia in 96-hour acute tests (LC50 88  ug/1) .
Pritchard, P.H.  1986.  Extrapolation of Laboratory Biodegradation
Information  to Microcosms and Field Studies: A Summary of Research  Results.
EPA/600/X-86/223, U.S. Environmental Protection Agency, Env.ironmental
Research Laboratory, Gulf Breeze, FL.  31p.

   The ability to extrapolate biodegradation information from the
   laboratory to the field has been examined. Site-specific
   extrapolations  were  performed  by comparing the  fate  of  p-cresol,
   p-nitrophenol,  fenthion,  p-chlorophenol  and a  complex  mixture  of
   hydrocarbons  in  sterile and nonsterile shake flasks  and  nticrocosms
   tests  with  the fate of each chemical following dosing into  a  field
   site. The field sites included a freshwater stream, an estuarine  salt
   marsh and a freshwater pond. Success in extrapolating laboratory  data
   to the field was a function of the environmental complexity that could
   be  modeled  in laboratory systems. Microcosms proved  to  be,  within
   certain limits, excellent analogs to field studies. Physical
   parameters, such as turbulent mixing and gaseous exchange in the water
   column, were the most difficult parameters to model.
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Pritchard,  P.H.  1986.  Fate of Pollutants.  J. Water Pollut.  Control  Fed.
58(6):635-645.  (ERL,GB 582).

   Published literature on the environmental fate of pollutants published
   during  1984  are  reviewed. Short excerpts are  presented  from  each
   reference covering such areas as photolysis, biodegradation,
   hydrolosis, sorption, and volatility for pollutants including
   pesticides, hydrocarbons, heavy metals, polynuclear hydrocarbons,  and
   other toxic organic chemicals.

Pritchard, P.H., C.R. Gripe, L.H. Mueller, and E.J. O'Neill.  1987.
Metabolism  of  Fenthion by  Aquatic  Microbial  Communities.  In:  Pesticide
Science and Biotechnology: Proceedings of the Sixth International Congress of
Pesticide Chemistry, IUPAC International Union of Pure and Applied Chemistry,
Ottawa, Canada, August 10-17, 1986.  R. Greenhalgh and T.R. Roberts, editors,
Blackwell  Scientific Publications, Boston, MA.  pp. 505-508.  (ERL,GB  592).
Avail, from NTIS, Springfield, VA: PB87-102430.

   The microbial metabolism of the mosquito control agent, fenthion,  has
   been studied in shake flask systems containing water and sediment from
   a  salt  marsh. The usefulness of this information in  describing  the
   fate  of fenthion in microcosms and in a field dosing  experiment  was
   determined.  Our  results show that microbial  cxamnunities  associated
   with  the  sediment,  the  presence of  invertebrate  animals  in  the
   sediment bed, and the anaerobic conditions of the sediment  contribute
   significantly  to  the  fate of  fenthion  under  natural  conditions.

Pritchard,  Parmely H., Carol A. Monti, Ellen J. O'Neill, John  P.  Connolly,
and  Donald  G. Ahearn.  1986.  Movement of Kepone  (Chlordecone)  Across  an
Undisturbed Sediment-Water Interface in Laboratory Systems.  Environ.
Toxicol. Chem.  5(7): 647-657.  (ERL,GB487).
Avail, from NTIS, Springfield, VA: PB87-169645.

   The  distribution  of  Kepone (chlordecone) in a  sediment  bed  after
   various  periods of continuous toxicant input to the  overlying  water
   column  was determined in a laboratory system. Most of the Kepone  was
   found  to  accumulate  in  the  top 0.6  to  1.5  cm  of  sediment.  A
   mathematical model was developed to predict Kepone concentrations with
   depth over time in the sediment. An equilibrium partition  coefficient
   was  determined  from batch sorption tests and a  molecular  diffusion
   coefficient  for Kepone was estimated from an  empirical  relationship
   between diffusivity and molecular weight. A computed Kepone
   distribution  based on diffusion rates that decreased with  depth  and
   with  incubation  time  gave the best fit to  the  observed  data.  We
   attribute the apparently faster rates in the upper sediment to  mixing
   between  interstitial and overlying water. Our results illustrate  the
   value of models in conjunction with laboratory studies in defining the
   interactions of pollutants with sediment beds.
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Pritchard,  Parmely  H.,  Ellen J. O'Neill, Carol M.  Spain,  and  Donald  G.
Ahearn.  In press. Physical and Biological Parameters That Determine the Fate
of  p-Chlorophenol  in Laboratory Test  Systems.  Appl.  Environ.  Microbiol.
25p.   (ERL,GB 609*).

   Shake flask and microcosm studies were conducted to determine the fate
   of para-chlorophenol (p-CP) in water and sediment systems and the role
   of  sediment and nonsediment surfaces in the  biodegradation  process.
   Biodegradation of p-CP in estuarine water samples in shake flasks  was
   slow  over incubation periods of 300 hours. The addition  of  detrital
   sediment resulted in immediate and rapid degradation evidenced by  the
   production of 14CO2 from [14C] p-CP. The addition of sterile sediment,
   glass  beads or sand resulted in an approximately 4 to 6 times  faster
   biodegradation  than  observed in the water alone. Densities  of  p-CP
   degrading  bacteria  associated with the detrital  sediment  were  100
   times  greater than those enumerated in water. Bacteria in  the  water
   and  associated with the sediment after preexposure of both water  and
   sediment to p-CP demonstrated enhanced biodegradation. In some
   microcosms,  p-CP was degraded completely in the top 1.0 cm of  intact
   sediment beds. Sediment reworking activities by benthic  invertebrates
   from  one site were sufficient to mix p-CP deep into the sediment  bed
   faster than biodegradation or molecular diffusion. p-CP was persistant
   at  lower depths of the sediment, possibly a result of reduced  oxygen
   conditions preventing aerobic biodegradation.

Rao, Kbthapalli Ranga, and Philip J. Conklin.  1986.  Molt-Related
Susceptibility  and  Regenerative  Limb Growth  as  Sensitive  Indicators  of
Aquatic  Pollutant  Toxicity to Crustaceans.  In:  Indian Ocean:  Biology  of
Benthic  Marine  Organisms: Techniques and Methods as Applied to  the  Indian
Ocean.  M. Thompson, R. Sarojini, and R. Nagabhushanam, editors, Oxford & IBH
Publishing Co., New Delhi, India,  pp. 523-534.  (ERL,GB X472*).
Avail, from NTIS, Springfield, VA: PB86-213741.

   This study evaluated the comparative toxicity of various pollutants to
   intermolt  and molting grass shrimp (Palaemonetes pugio). Most of  the
   tested materials (pentachlorophenol, tetrachlorophenols,
   tricnlorophenols, methylenebis dichlorophenol, dibutyl phthalate,
   chromium, and drilling mud) were more toxic to molting shrimp than  to
   intermolt  shrimp. Radiotracer studies with 2,4,5-trichlorophenol  and
   pentachlorophenol indicated that the increased susceptibility of newly
   molted shrimp is linked to increased pollutant uptake. Additional work
   showed that certain chlorophenols, dithiocarbamates, dibutyl
   phthalate,  and chromium cause inhibition of regenerative limb  growth
   in grass shrimp without affecting the molt cycle duration. The  median
   effective  concentrations  (ECSOs) for inhibition of limb  regeneration
   were well below the medial lethal concentration  (LCSOs) for  intermolt
   shrimp.  Thus, limb regeneration assays with intermolt shrimp as  well
   as toxicity tests with molting shrimp serve as sensitive indicators of
   aquatic pollutant toxicity.
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Ritchie,  Scott  A.,  and William P.  Davis.  1986.  Evidence  for  Embryonic
Diapause  in Rivulus raarmoratus: Laboratory and Field  Observations.  J.  Am.
Killifish Assoc.  19(1):103-108.  (ERL,GB 567).

   Among North American killifish species, diapause, or arrested
   embryonic development, has been infrequently noted. Marsh sods sampled
   from  natural  vegetated  swales yield hatched  F.  confluentus  15-30
   minutes after immersion in the laboratory following 2-3 months in  the
   field.  Time-series  observations  in  the  Collier  County  (Florida)
   Mosquito  Control District are reported. The uniform size of  the  fry
   collected  from the test site, and the brevity of immersion  (November
   1984-April  1985) before onset of rainy season, mitigate  against  the
   survival  of previously hatched fish, and argue in favor of  embryonic
   diapause.

Russell,  G.A.,  D.P.  Middaugh,  and  M.J.  Hemmer. In review.  Reproductive
Rhythmicity of the False Grunion, Colpichthys regis, from Estero del Soldado,
Mexico.  Calif. Fish Game.  12p.  (ERL,GB 586*).

   The reproductive rhythmicity of the false grunion, Colpichthys  regis,
   was  observed  in the Estero del Soldado, Mexico during  October  1982
   through  January 1983. Spawning runs occurred at approximately  2-week
   intervals  during daytime high tides. These high tides coincided  with
   new  and  full  moons. Spawning only  occurred  when  predicted  tidal
   heights  were  equal to or greater than 0.73 m above  MEW.  Eggs  were
   deposited  in the upper intertidal zone in locations that appeared  to
   provide  protection  from predators, thermal stress  and  desiccation.

Saye, D.J., O. Ogunseitan, G.S. Sayler, and R.V. Miller. In review. Potential
for Transduction of Plasmids in Pseudomonas aeruginosa in a Natural
Freshwater  Environment.  Appl.  Environ.  Microbiol.  34p.  (ERL,GB  X536*).

   The  transduction  of  Pseudomonas aeruginosa plasmid  Rmsl49  by  the
   generalized transducing phage phi DSl was shown to occur during a nine
   day incubation of environmental test chambers in a freshwater
   reservoir.  Plasmid  DNA was transferred from a  nonlysogenic  plasmid
   donor to a phi DSl lysogen of Pseudomonas aeruginosa that served  both
   as  the  source of the transducing phage and as the recipient  of  the
   plasmid  DNA.  Transduction  of the plasmid in  the  presence  of  the
   natural  microbial community of the reservoir was below the limits  of
   detection  employed. The results demonstrate that a  potential  exists
   for the transduction of plasmid DNA in aquatic habitats.
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Saye,  D.J.,  0.  Ogunseitan, G.S. Sayler, and  R.V.  Miller. In review.  The
Effect  of Plasmid Donor Concentration and a Natural Freshwater Community  on
Transduction  in  Pseudomonas  aeruginosa.  Appl.  Environ.   Microbiol.  27p.
(ERL,GB X538*).

   A series of environmental test chambers containing sterile lake  water
   were inoculated with nonlysogenic plasmid-containing Pseudomonas
   aeruginosa and a lysogen which served as both a source of  generalized
   transducing  phage and as a recipient of transduced ENA.  A  comparable
   series of test chambers was set up and included the natural  microbial
   coraraunity.  The concentration of donors introduced into  the  chambers
   was varied while the recipient concentration in each chamber was at  a
   level equivalent to natural concentrations of Pseudomonas. The
   transduction of the plasmid Rmsl49 in P. aeruginosa was shown to occur
   in the environmental test chambers during seven days of incubation  in
   a freshwater reservoir. Transduction was observed both in the  absence
   and  in the presence of the natural microbial community.  The  presence
   of  the natural community resulted in a rapid decrease in the  numbers
   of  the introduced donors and recipients and a decrease in the  number
   of  transductants recovered. The concentration  of  plasmid-containing
   donor cells introduced was shown to significantly effect the frequency
   of transduction. These results demonstrate the potential for naturally
   occurring transduction in aquatic environments and indicate that donor
   load  may  be  an important parameter  in  assessing  this  potential.

Sayler,  Gary S., Rakesh K. Jain, Andrew Ogram, Charles A.  Pettigrew,  Laura
Houston, James Blackburn, and William S. Riggsby. In review,. Applications for
ENA  Probes in Biodegradation Research.  Presented at the  4th  International
Symposium  on  Microbial Ecology, Ljubljana, Yugoslavia,  Aug.  24-29,  1986.
34p.  (ERL,GB X531*) .
Avail, from NTTS, Springfield, VA: PB87-145322.

   The use of ENA: ENA hybridization technology in biodegradation  studies
   is investigated. The rate constants for sediments exposed to synthetic
   oils  could  be calculated from the NAH+ genotypes and  this  approach
   would  be  useful in predicting the kinetics of  aromatic  hydrocarbon
   degradation. Gene probes prepared from NAH7 plasmid were also used  to
   monitor  and  enumerate  the naphthalene-degrading  populations  in  a
   continuous mixed culture bioreactor and this analysis demonstrated  at
   least  one order of magnitude difference in the  naphthalene-degrading
   population  over  the conventional plate analysis. It was  also  shown
   that using pSSSO (a chlorobiphenyl mineralizing plasmid)  as probe ENA,
   other polychlorinated biphenyls degrading organisms can be  identified
   from  the  environment. Further, the maintenance and  stability  of  a
   genetically  modified  Pseudomonas putida (carrying plasmids  TOL  and
   RK2)  over  an 8-week period in  chemically  contaminated  groundwater
   aquifer material was established. Results demonstrate the wide
   applications, signficances, sensitivity, and accuracy of ENA probes in
   environmental biodegradation research.
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School:,  W.P.,  D.E.  Williams, and J.J.  Lech. In review.  Combined  Use  of
Biochemical  Indicators  to Assess Sublethal Pollution  Effects  on  Fundulus
grandis, the Gulf Killifish.  Mar. Environ. Res.  16p.  (ERL,GB 565*).

   Sublethal  biochemical  markers  were used to  identify  liver  enzyme
   induction in fish from a bayou in Pensacola, Florida. Gulf  killifish,
   Fundulus grandis, from a nonpolluted site were used in the study which
   included laboratory-induced fish and their various controls as well as
   the  fish captured in the bayou. The biochemical markers  tested  were
   liver to body weight ratios, total content of cytochrame P-450,  mixed
   function  oxygenase and ethoxyresorufin-0-deethylase  activities,  and
   the  specific  induction of the LM4b isozyme of the  cytochrome  P-450
   system.  The  findings  suggest  that enzyme  induction  occurs  at  a
   sublethal  level,  indicating the presence of  liver  enzyme  inducing
   substances in the bayou.

Shirley,  Michael  A.,  and Charles  L.  McKenney,  Jr.  1987.  Influence  of
Lindane on Survival and Osmoregulatory/Metabolic Responses of the Larvae  and
Adults of the Estuarine Crab, Eurypanopeus depressus.  In:  Physiology
Pollution  of  Marine Organisms.  Winona B. Vernberg, editor,  University  of
South Carolina Press, Columbia, SC.  pp. 275-297.  (ERL,GB 562*).

   Short-term exposure to sublethal concentrations of the  organochlorine
   insecticide, lindane, caused alterations in ionic and osmotic
   regulatory abilities and related compensatory metabolic mechanisms  in
   the xanthid crab Eurypanopeus depressus. A lindane exposure
   concentration of 1.45 ug/L reduced hemolymph osmotic concentrations in
   adult  crabs;  however, chloride ion regulation  was  more  sensitive,
   being  disrupted  at a lindane exposure concentration  of  0.07  ug/L.
   Larval  stages  proved to be more sensitive to lindane  exposure  than
   adults. A lindane exposure concentration of 0.01 ug/L increased larval
   mortality and altered larval respiration and ammonia excretion  rates.
   Zoeae,  megalopae  and  adults of the crab, E.  depressus,  appear  to
   possess different response patterns to hypoosmotic stress and  lindane
   exposure.
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Sinclair,  James  L., and Martin Alexander. In review.  Effect  of  Bacterial
Growth  on  Protozoan Predation in the Presence of  Alternative  Prey.  Appl.
Environ. Microbiol.  19p.  (ERL,GB X537*).

   A  study  was conducted on the influence of growth  rate  and  initial
   population  size on the survival of bacteria subjected to  grazing  by
   protozoa.  In  a  mixture containing  Tetrahyinena  thermophila  and  a
   streptomycin-resistant Bradyrhizobium sp.,  the growth rate of
   Salmonella  thompson was varied by adding differing concentrations  of
   streptomycin.  S.  thompson  initially increased in  number,  but  the
   population  density fell as grazing pressure increased. The  organisms
   that grew the fastest in culture declined to a smaller extent than the
   slow  growers. The decline occurred in sewage containing protozoa  but
   not  in  samples from which protozoa had been  eliminated.  In  sewage
   inoculated  with  70  to 190 cells per ml of  the  test  species,  the
   densities of two of the three fast growing bacteria increased, but the
   numbers of the slow growing test organisms declined. In  protozoa-free
   sewage,  the  abundance  of the three fast growing but  not  the  slow
   growing  species  declined. In cultures containing T.  thermophila,  a
   test  bacterium, and a high desity of Enterobacter aerogenes cells  as
   alternative  prey, only a fast growing Pseudomonas sp. of  three  test
   bacteria  increased appreciably in abundance. Based on these data,  we
   suggest that in environments supporting active predation by  protozoa,
   bacterial  species that grow quickly and reach high deaisities will  be
   dominant among the surviving prey species.

Spain,  J.C., and C.C. Somerville. In review.  Biodegradation of Jet  Fuel  by
Aquatic Microbial Communities.  In:  Proceedings: 2nd International Symposium
on  Microbial-Enhanced Oil Recovery, Georgia State University,  Atlanta,  GA,
August  16,  1984.  Georgia  State  University,  Atlanta,  GA.  23p.  (ERL,GB
X485*).
Avail, from NTIS, Springfield, VA: PB85-191971.

   This  paper describes laboratory experiments that studied the fate  of
   jet  fuel in several types of situations that could be encountered  in
   the field. Benzene, toluene, and p-xylene were the only components  of
   the  fuel that dissolved in the water to  significant  concentrations.
   All three compounds volatilized within 24 h and, thus, did not  remain
   in  the  water long enough for microbial degradation to  affect  their
   fate.  Inclusion of sediment (500 mg/1 dry weight) did not retard  the
   disappearance of the fuel components, and rates of disappearance  were
   identical in controls sterilized with HgC12.
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Tagatz, M.E., R.S. Stanley, G.R. Plaia, and C.H. Deans.  1987.  Responses  of
Estuarine  Macrofauna  Colonizing Sediments  Contaminated  with  Fenvalerate.
Environ. Toxicol. Chera.  6:21-25.   (ERL,GB 569).

   Macrobenthic  animal  coraraunities that  colonized  uncontaminated  and
   fenvalerate-oontaminated sand (0.1, 1 and 10 ug/g dry weight, nominal)
   in  boxes  placed for 8 weeks in an estuary were  compared  to  assess
   effects  of  fenvalerate  on community structure. As much  as  27%  of
   initial  concentrations  of  this  synthetic  pyrethrin  persisted  in
   sediment at the end of the test. The average number of species  (35.6)
   in communities in five replicates exposed to 10 ug/g was significantly
   less  than that in the control (47.8) and lower  concentrations  (45.0
   and  46.2).  Of  the dominant  phyla  collected  (Annelida,  Mbllusca,
   Chordata,  and  Arthropoda), abundance of  chordates  only  (primarily
   lancelets, Branchiostoma caribaeum) was reduced by 10 ug
   fenvalerate/g.  Biological  indices  applied to the  data  showed  the
   greatest structural differences for communities exposed to the highest
   concentration,  but these did not differ substantially from those  for
   the control. Effective concentration for exposure via the sediment was
   five  orders  of magnitude greater than that for  waterborne  exposure
   determined in earlier benthic community studies.

Tagatz,  Marlin E., and Roman S. Stanley.  1986.  Results of  Acute  Toxicity
Testing  of  Single  Species Dominant in Benthic Qaratiunity  Testing  at  Gulf
Breeze,  Florida.  EPA/600/X-86/325,  U.S. Environmental  Protection  Agency,
Environmental Research laboratory,  Gulf Breeze, FL.  36p.

   This  report  gives the 96-hr acute toxicities  of  pentachlorophenol,
   fenvalerate,  dibutyl phthalate, or 1,2,4-trichlorobenzene to  various
   mollusks  (Laevicardium mortoni, Ensis minor, Mulinia  lateralis)   and
   annelids  (Armandia maculata, Neanthes succinea,  Capitella  capitata)
   and to an arthropod (Corophium acherusicum), echinoderm  (Leptosynapta
   inhaerens),  and a chordate (Molgula sp.). Species were selected  from
   those numerically dominant in earlier benthic community toxicity tests
   in  order  to allow comparison between results of single  species  and
   community  toxicity  tests.  Acute  test results are  presented  in  a
   series of tables.
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Tagatz, Marlin E.  1986.  Some Methods for Measuring Effects of Toxicants  on
Laboratory- and Field-Colonized Estuarine Benthic Coraraunities.  In:
Community Toxicity Testing, ASTM STP 920.  John Cairns,  Jr., editor, American
Society  for  Testing and Materials, Philadelphia,  PA.   pp.  18-29.  (ERL,GB
529).

   Effects of toxicants on estuarine macrobenthic animals that  developed
   in  sand-filled boxes in the laboratory and field during  eight  weeks
   were determined by comparing community' structures in control boxes and
   in  boxes  treated  with  a toxicant.  Boxes  were  colonized  in  the
   laboratory  by planktonic larvae in continuously  supplied  unf iltered
   seawater  and in the field by animals that occurred  naturally.  Field
   boxes  were placed in estuarine waters, either near the laboratory  or
   at  salt-marsh  sites subjected to contamination by  mosquito  control
   pesticide  applications. Eight separate studies were  conducted  using
   the  same  test materials in laboratory and field  tests.  Communities
   that developed were diverse and averaged 1441 individuals, 30 species,
   and 6 phyla for laboratory tests and 933 individuals, 51 species,  and
   8 phyla for field tests. Toxicants were introduced via water, air,  or
   sediment  and  before,  during,  or  after  colonization.  Tests  with
   laboratory-  and  field-colonized communities  provided  corroborating
   data  as  well  as  date  unique  to  each  test.  Various  structural
   attributes  among  laboratory, experimental field, and  natural  field
   communities  were  similar,  indicating that  data  derived  from  the
   laboratory  and  field  toxicity tests  can  have  good  environmental
   applicability.

Tagatz,  Marlin E., Gayle R. Plaia, and Christine H.  Deans.  1986.  Toxicity
of Dibutyl Phthalate-tontaminated Sediment to Laboratory- and Field-Colonized
Estuarine Benthic Communities.  Bull. Environ. Contam. Toxicol.
37(1):141-150.   (ERL, GB 547).
Avail, from NITS, Springfield, VA: PB87-152815.

   Dibutyl  phthalate   (DBF),  one of a large class of  alkyl  esters  of
   1,2-benzene dicarboxylic acid, is used widely in the United States and
   other countries as a plasticizer for epoxy and PVC resin.  Significant
   amounts  of DBF commonly occur in the aquatic  environment,  including
   the sediment. Its octanol^water partition coefficient of 5.2 (US  EPA
   1979) indicates that sorption of DBF by sediment could be  substantial
   in waters polluted by this chemical. Concentrations as high as 89  ppb
   have  been reported in sediment samples from Chesapeake Bay and up  to
   15.5  ppm in those from the Rhine River. To obtain information on  the
   effects  of DBF on estuarine communities exposed via the sediment,  we
   investigated the responses of macrobenthic animals that colonized sand
   contaminated with this chemical in the laboratory and field.

Tan, B., and Melius P,  1986.  Polynuclear Aromatic Hydrocarbon Metabolism in
Fishes.  Comp. Biochem. Physiol. C Comp. Pharmacol. Toxicol.  83C(2):217-224.
(ERL,GB X513*).

   The metabolism of PAHs in fishes is reviewed. Oxygenated, and
   hydroxylated  Phase  I metabolites of PAHs in fish are  compared  with
   each other and with those of other mammals. The review emphasizes  the
   metabolites  and  not the metabolizing enzymes in many  fish  species.
   Some  implications  of  chemical carcinogenesis  also  are  discussed.
                                 PAGE  44

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Trevors,  J.T., T. Barkay, and A.W. Bourquin. In review. Gene Transfer  Among
Bacteria  in  Soil and Aquatic Environments: A  Review.  Can.  J.  Microbiol.
27p.  (ERL,GB 584*) .

   The  exchange of genetic material between microorganisms in  soil  and
   aquatic  environments  is  considered in light  of  the  potential  of
   foreign  gene  desamination from engineered  organisms  to  indigenous
   bacteria.  Abundant indirect evidence suggests that  natural  isolates
   can  serve as donors and recipients of genetic material. Studies  have
   mostly documented such transfer of plasmid coded antibiotic and  metal
   resistances.  However,  the  scarce  information  which  is  available
   indicates  that in situ gene transfer occurs at very  low  frequencies
   due  to  biological and physical parameters of the  soil  and  aquatic
   environments.

Walker,  W.W.,  C.R.  Gripe, P.H. Pritchard, and  A.W.  Bourquin.  In  press.
Biological and Abiotic Degradation Rates of Xenobiotic Chemicals in In  Vitro
Estuarine  and Sediment/Water Systems.  J. Agric. Food Chem.  (ERL,GB  504*).

   Three herbicides, two fungicides, four organophorphorus  insecticides,
   and  one  miticide  (acaricide) were  characterized  with  respect  to
   degradation rate in estuarine water and sediment/water systems using a
   simple shake flask test. Decay rates for each chemical could generally
   be described by a first order model. The degradation of hoelon, bravo,
   bolstar,  fenthion, and bolero was biologically mediated. The  fastest
   biodegradation rates occurred when sediment was present. The
   degradation of trifluralin, dursban, phorate, EPN and
   pentachloronitrobenzene  were primarily by abiotic means. Relative  to
   the other test materials, phorate and bravo,  pentachloronitrobenzene,
   trifluralin,  and  bolstar reflected intermediate  degradation  rates.
   Variability in rates from replicate flasks suggested that a difference
   in rate within treatments (sterile/active, with and without sediments)
   of a factor of two or less was probably not significant.

Walsh,  Gerald E., Christine H. Deans, and Leslie L.  Mclaughlin.  In  press.
Comparison  of  Four Methods for Calculating the EC50 from  Algal  Population
Growth.  Environ. Toxicol. Chem.  8p.  (ERL,GB 588*).

   EC50s (calculated concentrations that would inhibit growth by 50%)  of
   21  pesticides in unicellular algal toxicity tests were calculated  by
   straight-line  graphical interpolation, moving average  interpolation,
   probit  analysis  and the binomial method. ECSOs of 18  tin  compounds
   were calculated by graphical interpolation, moving average and  probit
   methods.  A total of 187 tests was analyzed. Values of the  EC50  were
   essentially  indentical  when  calculated by each method,  and  it  is
   concluded that straight-line graphical interpolation, the simplest and
   most  rapid method, can be used to estimate relative toxic  effect  on
   algal population growth.
                                 PAGE  45

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Walsh, Gerald E., Leslie L. Mclaughlin, Michael K. Louie, Christine H. Deans,
and  Emile  M. Lores.  1986.  Inhibition of Arm  Regeneration  by  Ophioderma
brevispina (Echinodermata, Ophiuroidea) by Tributyltin Oxide and Triphenyltin
Oxide.  Ecotoxicol. Environ. Saf.  12(1):95-100.  (ERL,GB 528).

   Effects  of  water-bourne  toxicants on regeneration of  arms  by  the
   brittle  star, Ophioderma brevispina, are described. Regeneration  was
   inhibited by 0.1 ug liter-1 bis(tri-n-butyltin)oxide and
   bis(triphenyltin)oxide.  Both  substances are known to  act  upon  the
   nervous  system,  and it is suggested that inhibition  was  caused  by
   neurotoxicological  action  of the tin compounds or  by  their  direct
   effect  upon tissue at the breakage point. The former is  roost  likely
   because  regeneration  is  mediated by the radial  nerves  of  brittle
   stars.

Walsh, Gerald E., Michael K. Louie, Leslie L. Mclaughlin, and Emile M. Lores.
1986.  Lugworm   (Arenicola cristata) larvae in Toxicity Tests:  Survival  and
Development When Exposed to Organotins.  Environ. Toxicol. Chem.
5(8):749-754.   (ERL,GB 521).
Avail, from NTIS, Springfield, VA: PB87-171120.

   A test is described for the exposure of the lugworm Arenicola cristata
   to toxicants. Embryos of A. cristata were exposed for 96 and 168 h  to
   bis(triphenyltin) oxide  (TPTO), triphenyltin chloride (TPTC),
   bis (tri-n-butyltin)  oxide (TBTO) and tributyltin acetate  (TBTA).  The
   toxic effects were death and abnormal development of larvae.
   Concentrations  that killed all animals were 4 ug L-l (96 h) and 2  ug
   L-l (168 h) TPTO; 10 ug L-l (96 h) and 5 ug L-l  (168 h) TPTC; 4 ug L-l
    (96 h) TBTO; and 10 ug L-l (96 h) and 5 ug L-l (168 h) TBTA.  Abnormal
   morphology was caused by 0.75 ug L-l TPTO, 1 ug L-l TPTC and 5 ug  L-l
   TBTA.  Several developmental stages, from embryo to  swimming  larvae,
   were exposed to TPTO. The most sensitive stages were early trochophore
   and  early  settled stage. The range of  concentrations  between  100%
   survival  and  100% mortality was narrow in all  tests.  The  exposure
   system is simple and detects teratogenicity.

Walsh,  Gerald E.  1986.  Organotin Toxicity Studies Conducted with  Selected
Marine  Organisms  at EPA's Environmental Research laboratory,  Gulf  Breeze,
Florida.  In:  TEKF1 Oceans  '86 Conference Proceedings,  pp. 1210-1212.
(ERL,GB 585).
Avail, from NITS, Springfield, VA: PB87-102539.

   Studies on effect of bis (tri-n-butyltin) oxide  (TBTO) and other
   organotins on marine species have been conducted at the U.S.
   Environmental Protection Agency's laboratory at Gulf Breeze,  Florida,
   since  1983.  First  studies  were  done  on  two  species  of  algae,
   Skeletonema costatum and Thalassiosira pseudonana, where 72h ECSOs for
   tributyltins and population growth were 0.35 and 1.16 ug/1,
   respectively.  Two  developmental  stages of  the  lugworm,  Arenicola
   cristata,  were  sensitive to TBTO  (96h LC50=4 ug/1).  Only  0.1  ug/1
   inhibited arm regeneration by the brittle star, Ophioderma brevispina.
   TBTO  was  less toxic to the grass shrimp,  Palaemonetes  pugio,   (96h
   IC50=20 ug/1). Continuing studies include research on effects of  TBTO
   on  1-, 4- and 10-day-old mysids and estuarine  seagrass  communities.
                                 PAGE  46

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Walsh,  Gerald  E. In review.  Principles of  Toxicity  Testing  with  Marine
Unicellular Algae.  Environ. Toxicol. Chem.  23p.   (ERL,GB 606).

   Toxicity  testing with unicellular algae requires application  of  the
   principles  of phycology and microbiology to culturing, handling,  and
   exposing  the organisms. This brief review describes major aspects  of
   algal toxicity testing, including growth curves, factors that
   influence  population  growth in culture (light,  temperature,  medium
   composition, pH, and salinity), choice of test species, measurement of
   population  density, enumeration of living and dead  cells,  numerical
   expression of toxic effects, and bioaccumulation.

Walsh,  Gerald E., Mark J. Yoder, Leslie L. Mclaughlin, and Emile  M.  Lores.
In review.  Responses  of Marine  Unicellular  Algae  to  Brominated  Organic
Compounds in Six Growth Media.  Mar. Environ. Res.  (ERL,GB 597*).

   Marine unicellular algae, Skeletonema costatum, Thalassiosira
   pseudonana, and Chlorella sp., were exposed to the industrial
   brominated compounds, tetrabromobisphenol A (TBBP),
   decabromobiphenyloxide  (DBBO), hexabromocyclododecane  (HBCD),
   pentabrconomethylbenzene (PBMB), pentabromoethylbenzene (PBEB), and the
   herbicide,  bromoxynil  (BROM), in six algal growth  media.  Saturation
   concentrations  of DBBO (1 mg/1), PBMB (1 mg/1), and PBEB  (0.5  mg/1)
   reduced  growth by less than 50%. ECSOs of the other compounds  varied
   with  growth  medium, with high EC50/low EC50 ratios between  1.3  and
   9.9.  Lowest ECSOs, 9.3 to 12.0 ug/1, were obtained with  S.  costatum
   and  HBCD.  It is concluded that responses to toxicants  in  different
   media  are the results of interactions between algae,  growth  medium,
   toxicant, and solvent carrier.

Walsh,  Gerald  E.  1986.  Techniques  for Study of  Effects  and  Uptake  of
Sediment-Associated Chemicals.  EPA/600/X-86/134, U.S. Environmental
Protection Agency, Environmental Research Laboratory, Gulf Breeze,  FL.  41p.

   Methods for exposure of epibenthic and benthic marine invertebrates to
   contaminated  sediments  are  described.  The  following  concerns  are
   addressed:  choice  of test organisms, composition  of  the  sediment,
   toxicological  endpoints,  uptake and depuration. Test  animals  were:
   Emerita  talpoida  (mole crab), Uca pugilator and  U.  minax  (fiddler
   crabs),  Palaemonetes  pugio (grass shrimp),  Penaeus  dourarum  (pink
   shrimp)  and  Branchiostoma caribaeum (amphioxus).  The  animals  were
   exposed  to  fenthion, fenvalerate, bis  (tri-n-butyltin)   oxide,  bis
   (triphenyltin) oxide, cypermethrin, 1,2,4-trichlorobenzene, di-n-butyl
   phthalate  and  PCBs.  It is concluded that  organic  matter  must  be
   present  in  sediment  for  retention  of  toxic  chemicals,  chemical
   partitioning of toxicants between pore water and sediment particles is
   an important factor that controls toxicity,  quantitative  partitioning
   of  toxicants can be predicted for substances such as  pesticides  and
   organotins  and exposed animals accumulate toxicants  from  sediments,
   but depurate them when transferred to an uncontaminated environment. A
   list  of recommendations for future studies on contaminated  sediments
   is given.
                                 PAGE  47

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Walsh,  Gerald E.  1986.  Use of Plankton in Aquatic  Toxicity  Testing.  In:
Proceedings of the Third International Course in Toxicology and
Ecotoxicology,  Herriot-Watt  University, Edinburgh,  Scotland,  Sept.  6-13,
1985.  J.H.  Duffus, editor, WHO.  pp. 147-177.  (ERL,GB  551*).

   Aquatic  toxicology  is  the qualitative  and  quantitative  study  of
   adverse or toxic effects of chemicals and other anthropogenic
   materials on populations of aquatic organisms. It includes  laboratory
   studies  and  the  field of ecotoxicology,  which  is  concerned  with
   effects  of  human activities on naturally-occurring  populations  and
   communities  at  sites  in nature. Important data  for  evaluation  of
   effects  of  toxicants on aquatic systems are gained  from  work  with
   freshwater  and marine plankton. The following discussion is  designed
   to  give a brief explanation of the principles of  aquatic  toxicology
   demonstrated  by  tests  with plankton. I have  interpreted  the  term
   "plankton" loosely, to include fish eggs and small swimming forms such
   as  daphnids and mysids. Recent published works that  exemplify  these
   principles and that contain important literature references are given.
   This  work stresses methods and principles, and may be read  with  the
   author's  previous  contribution  (Walsh, 1983)  to  the  WHO  toxicity
   course,  which  reviews published effects of  toxicants  on  plankton.

Wang, Yei-Shung, Eugene L. Madsen, and Martin Alexander.  In press.
Biodegradation  by  Mineralization  or Cometabolism  Determined  by  Chemical
Concentration and Environment.  Appl. Environ. Microbiol.  17p.  (ERL,GB
X489*).

   Mbnuron  [3-(4-cMorophenyl)-l,l-dimethylurea]  was  mineralized  when
   added  to  sewage  at a concentration of 10 ug/L but not  a  10  mg/L.
   Organic products were formed at both concentrations. Products with the
   chromatograpihic characteristics of 4-chlorophenylurea and
   4-chloroaniline were generated during the decomposition of the  higher
   herbicide concentration. Diuron [3-(3,4-dichlorophenyl)-lr
   1-dimethylurea] and linuron [3-(3,4-dichlorophenyl)-l-
   methoxy-1-methylurea]  were  mineralized  when added to  sewage  at  a
   concentration  of  500  ng/L  but not at 2.0  mg/L.  No  evidence  for
   cometabolism  of  the  higher  levels  of  these  two  herbicides  was
   obtained,  but significant amounts of an unknown product  appeared  at
   the lower diuron levels. Chlorobenzilate  (ethyl
   4,4'-dichlorobenzilate) was cometabolized in water samples from  Beebe
   Lake and mineralized if the samples also contained freshwater
   sediments.  Mineralization  did  not occur if  glucose  and  inorganic
   nutrients were added to sediment-free lake water. Chlorobenzilate  was
   transformed  to organic products but not to C02 by  microorganisms  in
   water samples from three other lakes, but the pesticide was
   mineralized in sediment-containing water from two of those lakes.  The
   results  thus  show  that  a pesticide may  be  cometabolized  at  one
   concentration or in samples from one type of environment cind
   mineralized  at a lower concentration or in samples from  a  different
   type of environment.
                                 PAGE  48

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Wolf, P.H., J.T. Winstead, and J.A. Couch. In review. Proctoeces sp.
 (Trematoda:  Digenea)  in  Australian Oysters,  Saccostrea  coraraercialis  and
Crassostrea amasa.  Trans. Am. Micros. Soc.  (ERL,GB 605*).

   The  occurrence of Protoeces sp., a cosmopolitan digenetic  trematode,
   is reported from two different species of Australian oysters. The  low
   prevalence of the helminth is attributed to the intertidal environment
   inhabited by the Australian oysters.

Wortman, A.T., C.C. Somerville, and R.R. Colwell.  1986.  Chitinase
Determinants  of  Vibrio  vulnificus:  Gene Cloning  and  Applications  of  a
Chitinase  Probe.  Appl. Environ. Microbiol.  52(1):142-145.  (ERL,GB  X515).
Avail, from NTIS, Springfield, VA: PB87-152625.

   To  initiate study of the genetic control of chitinolytic activity  in
   vibrios,  the chitobiase gene was isolated by cloning chromosomal  ENA
   prepared  from Vibrio vulnificus. Chimeric plasmids  were  constructed
   from  Sau3A  I  partial digests of chromosomal ENA by  ligating  5  to
   15-Kilobase fragments into the BamHI site, i.e., in the Tc(r) gene, of
   pBR322  (Am(r)Tc(r)).  The resulting plasmids  were  transformed  into
   Escherichia coli EH1. Chitobiase activity of the insert-bearing clones
   was detected by using a chromogenic substrate,
   p-nitxophenyl-N-acetYlB,D-glucosaminide, and confirmed by the
   appearance  of  a  fluorescent  end product  from  the  hydrolysis  of
   4-methylumbellif eryl-B, D-N-N' -diacetylchitiobiose. Endochitinase
   activity  was  demonstrated by liberation  of  water-soluble  products
   produced  by the degradation of [3H]chitin. Transformation of E.  coli
   Y1QR (lacY) with plasmids from chitinase-positive clones restored  the
   lactose-positive  phenotype,  suggesting the presence  of  a  permease
   associated  with  Chitinase  activity. Physical  mapping  of  plasmids
   containing  the Chitinase determinants indicate that transcription  of
   these genes in E. coli may be inititated at a V. vulnificus  promoter.
                                 PAGE  49

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KEYWORD TITLE INDEX
      PAGE  50

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     A
                    merit-Bound PCBs by Fiddler Crabs                     5- 1
     11              sstion Rate /, Bioaccuraulation of Kepone by Spot (L  18- 1
Across an Uno^...     1 Sediment-Water Interface in Laboratory Systems /  37- 3
Acute Toxicity Hai^jook of Chemicals to Estuarine Organisms             26-1
  11   Lethal Responses of Bay Mysids (Mysidopsis bahia) to Three Insec   3- 1
  11   Toxicity Testing of Single Species Dominant in Benthic Community  43- 2
Adults of the Estuarine Crab, Eurypanopeus depressus /,Influence of Li  41- 2
Aerobic Biodegradation of Trichloroethylene                             31-1
   "    Metabolism of Trichloroethylene by a Bacterial Isolate          31-2
Age-Specific Growth /, Influence of the Organophosphate Insecticide Fen  27- 2
Alachlor and Propachlor in Suspensions of Pretreated Soils and in Samp  32- 1
Algae /,Effects of Drilling Fluids on Thalassia testudinum and Its Epi  35- 2
Amphioxus  (Branchiostoma caribaeum) /,Waterborne and Sediment-Source T   8-2
Aquatic Risk Assessment Research /, Biotechnology                         3-2
   11    Animals in Field Studies /,Cage for Use with Small              22- 1
   11    Microbial Communities /,Degradation of Jet and Missile Fuels b  36-2
   11    Environments /,Evidence for Genetic Modification of Microorgan   9- 1
   11    Microbial Communities /,Metabolism of Fenthion by               37- 2
   11    Pollutant Toxicity to Crustaceans /,Molt-Related SusceptiMlit  38-2
   "    Pollutants /,Role of Rivulus marmoratus in Research on          15- 1
   "    Toxicity Testing /,Use of Plankton in                           48- 1
Aquifers /,Metabolism of Alachlor and Propachlor in Suspensions of Pre  32- 1
Arenicola cristata) larvae in Toxicity Tests: Survival and Development  46-2
Arm Regeneration by pphioderma brevispina (Echinodermata, Ophiuroidea)  46-1
Aromatic Biodegradative Pathway /,Biodegradation of Trichloroethylene   31-3
   11     Compounds by Caulobacter crescentus /,Metabolism of             4-3
   11     Hydrocarbon Metabolism in Fishes /,Polynuclear                 44- 3
Atherinid Fishes /,Methods for Spawning, Culturing and Conducting Toxi  29- 3
Atherinidae) with Notes on Survival and Growth of Larvae at Different   29- 2
                                     B
Bacterial Isolate /,Aerobic Metabolism of Trichloroethylene by a        31- 2
    "     Inhibitors in Lake Water                                      24- 2
    11     Phenotypes /,Use of DNA:DNA Colony Hybridization in the Rapi  35- 1
Bahamas /,Laboratory Spawning, Egg Membranes, and Egg Capsules of 14 S  14- 3
bahia) to Three Insecticides /,Effects of Salinity Change on Acute Let   3- 1
  11   Exposed During a Complete Life Cycle: I. Survival, Reproduction,  27- 2
  "    /, Toxicity of Used Drilling Fluids to Mysids (Mysidopsis         21-1
Bay Mysids  (Mysidopsis bahia) to Three Insecticides /,Effects of Salin   3- 1
Benthic Communities /,Field Validation of Multi-Species Laboratory Tes  16- 1
   11    (immunity Testing at Gulf Breeze, Florida /,Results of Acute T  43- 2
   11    Communities /,Some Methods for Measuring Effects of Toxicants   44- 1
   11    Osmmunities /,Toxicity of Dibutyl Phthalate-Contaminated Sedim  44- 2
beryllina and M. peninsulae  (Pisces, Atherinidae) with Notes on Surviv  29- 2
beta) and Results Using Chlorpyrifos /,Early life-Stage Toxicity Test   23- l
Bimini, Bahamas /,Laboratory Spawning, Egg Membranes, and Egg Capsules  14- 3
Bicacxannulatipn of Kepone by Spot  (Leiostomus xanthurus): Importance o  18- 1
Biochemical Biological Control Agents on Metamorphosis of Marine Crust  28- 1
Biodegradation of Trichloroethylene /,Aerobic                           31-1
      11        of Trichloroethylene and the Involvement of an Aromatic  31- 3
      "        Information to Microcosms and Field Studies: A Summary   36-3
Biodegradative Pathway /,Biodegradation of Trichloroethylene and the I  31-3
Biological Control Agents on Metamorphosis of Marine Crustacea /,Metho  28- 1
Biotechnology Aquatic Risk Assessment Research                           3- 2
Bound PCBs by Fiddler Crabs /,Accumulation of Sedijment-                  5- 1
Branchiostoma caribaeum) /,Waterborne and Sediment-Source Toxicities o   8-2
brevispina  (Echinodermata, Ophiuroidea) by Tributyltin Oxide and Triph  46- 1
                                     C
Cage for Use with Small Aquatic Animals in Field Studies                22- 1
                                   PAGE  51

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                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     C
Caged Estuarine Animals Exposed to Fenthion in the Field /, Comparison    5- 2
Capsules of Eleven Marine Prosobranchs from Northwest Florida /,Egg     14- 2
   11     of 14 Small Marine Prosobrancns from Florida and Bimini,  Baha  14- 3
Captured near Drilling Platforms in the Gulf of Mexico /, Lesions in Fi  22- 3
caribaeum) /,Waterborne and Sediment-Source Toxicities of Six Organic    8- 2
Caulobacter crescentus /,Metabolism of Aromatic Compounds by             4-3
Chemicals to Estuarine Organisms /,Acute Toxicity Handbook of           26-1
    11     /,Techniques for Study of Effects and Uptake of Sediment-Ass  47- 3
    11     to Grass Shrimp (Palaemonetes pugio) and Amphioxus (Branchio   8- 2
Chitinase Probe //Chitinase Determinants of Vibrio vulnificus: Gene Cl  49- 2
    "     Determinants of Vibrio vulnificus: Gene Cloning and Applicat  49- 2
Chlordecone) Across an Undisturbed Sediment-Water Interface in Laborat  37- 3
Chlorobiphenyl Degradative Bacterial Phenotypes /,Use of DNA:DNA Colon  35-1
Chlorpyrifos /,Early Life-Stage Toxicity Test Methods for Gulf Toadfis  23- 1
     "       /,Effects of Diet Quantity on Sheepshead Minnows (Cyprino  12- 1
Chronic Toxicity Tests with Fish /,Relation of Survival to Other Endpo  26-2
Cleanup Method for Organophosphorous Pesticides /,Improved Silica Gel   25- 2
Cloning and Applications of a Chitinase Probe //Chitinase Determinants  49- 2
Coastal Waters: Issues for Consideration from a Regulatory Point of Vi  19- 1
Colonized Estuarine Benthic Corarnunities /,Some Methods for Measuring E  44- 1
    11     Estuarine Benthic Communities /,Toxicity of Dibutyl Phthalat  44- 2
Colonizing Sediments Contaminated with Fenvalerate /,Responses of Estu  43- l
Colony Hybridization in the Rapid Isolation of 4-Chlorobiphenyl Degrad  35- 1
Ctommunities /,Degradation of Jet and Missile Fuels by Aquatic Microbia  36-2
     11      /,Field Validation of Multi-Species laboratory Test System  16- 1
     11      /, Metabolism of Fenthion by Aquatic Microbial               37- 2
     11      //Some Methods for Measuring Effects of Toxicants on Labor  44- 1
     11      /,Toxicity of Dibutyl Phthalate-Contaminated Sediment to L  44- 2
Community Approach / Impact of Drilling Fluids on Seagrasses: An Exper  30- 2
    "     Testing at Gulf Breeze, Florida //Results of Acute Toxicity   43- 2
Comparison of Laboratory Toxicity Test Results with Responses of Caged   5- 2
Conducted with Selected Marine Organisms at EPA's Environmental Resear  46-3
Conducting Toxicity Tests with Early Life Stages of Atherinid Fishes /  29- 3
Consideration from a Regulatory Point of View //Integration of Monitor  19- 1
Contaminated with Fenvalerate //Responses of Estuarine Macrofauna Colo  43-1
     "       Sediment to Laboratory- and Field-Colonized Estuarine Ben  44- 2
Crab, Eurypanopeus depressus /,Influence of Lindane on Survival and Os  41- 2
Crabs /,Accumulation of Sediment-Bound PCBs by Fiddler                   5- 1
crescentus /,Metabolism of Aromatic Compounds by Caulobacter             4- 3
cristata) Larvae in Toxicity Tests: Survival and Development When Expo  46- 2
Critical Responses of Populations of Crustacea to Toxicants             27- 1
Crustacea to Toxicants //Critical Responses of Populations of           27- 1
    "     /,Methods for Determining the Influence of Biochemical Biolo  28- 1
Crustaceans /,Melt-Related Susceptibility and Regenerative Limb Growth  38- 2
Culturing and Conducting Toxicity Tests with Early life Stages of Athe  29- 3
Cycle: I. Survival, Reproduction, and Age-Specific Growth /,Influence   27- 2
Cyprinodon variegatus) During Early Life-Stage Exposures to Chlorpyrif  12- 1
                                     D
Degradation of Jet and Missile Fuels by Aquatic Microbial Qammunities   36- 2
Degradative Bacterial Phenotypes //Use of DNA:DNA Colony Hybridization  35- 1
depressus //Influence of Lindane on Survival and Csnoregulatory/Metabo  41- 2
Determinants of Vibrio vulnificus: Gene Cloning and Applications of a   49- 2
Determining the Influence of Biochemical Biological Control Agents on   28- 1
Development as an MPCA for Nontarget Risk //Evaluation of a Fungal Age  19- 2
     11      When Exposed to Organotins //Lugworm (Arenicola cristata)   46- 2
Diapause in Rivulus marmoratus: laboratory and Field Observations /,Ev  39- 1
Dibutyl Phthalate-Contaitilnated Sediment to Laboratory- and Field-Colon  44- 2
Diet Quantity on Sheepshead Minnows (Cyprinodon variegatus)  During Ear  12- 1
                                   PAGE  52

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     D
Dietary Accumulation and Ingestion Rate /,Bioaccumulation of Kepone by  18- 1
DNA:DNA Colony Hybridization in the Rapid Isolation of 4-Chlorobipheny  35- 1
 11  Colony Hybridization in the Rapid Isolation of 4-Cnlorobiphenyl De  35- 1
Dominant in Benthic Gammunity Testing at Gulf Breeze, Florida /,Result  43- 2
Drilling Fluids on Thalassia testudinum and Its Epiphytic Algae /,Effe  35- 2
   "     Fluids on Seagrasses: An Experimental ODramunity Approach /,Im  30-2
   11     Platforms in the Gulf of Mexico /,Lesions in Fishes Captured   22- 3
   11     Fluids to Mysids (Mysidopsis bahia) /,Toxicity of Used         21- 1
                                     E
Echinodermata, Ophiuroidea)  by Tributyltin Oxide and Triphenyltin Oxid  46- 1
Egg Capsules of Eleven Marine Prosobranchs from Northwest Florida       14- 2
 11  Membranes, and Egg Capsules of 14 Small Marine Prosobranchs from F  14- 3
 11  Capsules of 14 Small Marine Prosobranchs from Florida and Bimini,   14- 3
Eleven Marine Prosobranchs from Northwest Florida /,Egg Capsules of     14- 2
Embryonic Diapause in Rivulus marmoratus: Laboratory and Field Observa  39- 1
Emersion in the Mangrove Forest Fish Rivulus marmoratus: A Unique Resp   1- 1
Environmental Research Laboratory, Gulf Breeze, Florida /,0rganotin To  46- 3
Environments /,Evidence for Genetic Modification of Microorganisms Occ   9- 1
EPA's Environmental Research Laboratory, Gulf Breeze, Florida /,0rgano  46- 3
Epiphytic Algae /,Effects of Drilling Fluids on Thalassia testudinum a  35- 2
Estuarine Organisms /,Acute Toxicity Handbook of Chemicals to           26-1
    "     Animals Exposed to Fenthion in the Field /,Comparison of Lab   5- 2
    11     Benthic Communities /,Field Validation of Multi-Species Labo  16- 1
    11     Crab, Eurypanopeus depressus /,Influence of Lindane on Survi  41-2
    11     Macrofauna Colonizing Sediments Contaminated with Fenvalerat  43- 1
    11     Benthic Communities /,Some Methods for Measuring Effects of   44- 1
    "     Benthic Communities /,Toxicity of Dibutyl Phthalate-Contamin  44- 2
Eurypanopeus depressus /,Influence of Lindane on Survival and Osmoregu  41-2
Extrapolation of Laboratory Biodegradation Information to Microcosms a  36-3
                                     F
Fate of Pollutants                                                      37- 1
Fenthion in the Field /,Comparison of Laboratory Toxicity Test Results   5- 2
   "     /,Field and Laboratory Toxicity Tests with Shriirp, Mysids, an   7-1
   11     on Mysidopsis bahia Exposed During a Complete Life Cycle: I.   27- 2
   "     by Aquatic Microbial Oanmunities /, Metabolism of               37- 2
Fenvalerate /,Responses of Estuarine Macrofauna Colonizing Sediments C  43- 1
Fiddler Crabs /,Accumulation of Sediment-Bound PCBs by                   5-1
Field Studies /,Cage for Use with Small Aquatic Animals in              22- 1
  11   /,Comparison of Laboratory Toxicity Test Results with Responses    5- 2
  "   Observations /,Evidence for Embryonic Diapause in Rivulus marmor  39- 1
  11   Studies: A Summary of Research Results /,Extrapolation of Labora  36-3
  "   Validation of Multi-Species Laboratory Test Systems for Estuarin  16- 1
  11   and laboratory Toxicity Tests with Shrimp, Mysids, and Sheepshea   7- 1
  11   Colonized Estuarine Benthic Communities /,Some Methods for Measu  44- 1
  11   Colonized Estuarine Benthic Communities /,Toxicity of Dibutyl Ph  44- 2
Fish Rivulus marmoratus: A Unique Response to Hydrogen Sulfide /,Emers   1- 1
 11   /,Relation of Survival to Other Endpoints in Chronic Toxicity Tes  26-2
Fishes Captured near Drilling Platforms in the Gulf of Mexico /, Lesion  22- 3
  11    /,Methods for Spawning, Culturing and Conducting Toxicity Tests  29- 3
  11    /,Polynuclear Aromatic Hydrocarbon Metabolism in                 44- 3
Florida /,Egg Capsules of Eleven Marine Prosobranchs from Northwest     14- 2
   "    and Bimini, Bahamas /,Laboratory Spawning, Egg Membranes, and   14- 3
   11    /,Organotin Toxicity Studies Conducted with Selected Marine Or  46-3
   11    /,Results of Acute Toxicity Testing of Single Species Dominant  43- 2
Fluids on Thalassia testudinum and Its Epiphytic Algae /,Effects of Dr  35- 2
  11    on Seagrasses: An Experimental (Community Approach /,Impact of D  30- 2
  "    to Mysids (Mysidopsis bahia)  /,Toxicity of Used Drilling         21- 1
Forest Fish Rivulus marmoratus: A Unique Response to Hydrogen Sulfide    1- 1
                                   PAGE  53

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     F
Fuels by Aquatic Micrpbial Communities /, Degradation of Jet and Missil  36-2
Fungal Agent (Lagenidium giganteum)  Under Development as an MPCA for N  19- 2
                                     G
Gel Cleanup Method for Organqphosphorous Pesticides /,Improved Silica   25- 2
Gene Cloning and Applications of a Chitinase Probe /,Chitinase Determi  49- 2
Genetic Modification of Microorganisms Occurring in Natural Aquatic En   9-1
giganteum) Under Development as an MPCA for Nontarget Pdsk /,Evaluatio  19- 2
Grass Shrimp (Palaemonetes pugio) and Amphioxus (Branchiostoma caribae   8- 2
Ground Water Aquifers /,Metabolism of Alachlor and Propachlor in Suspe  32- 1
Growth /, Influence of the Organophosphate Insecticide Fenthion on Mysi  27- 2
  11    of larvae at Different Salinities /,Laboratory Spawning Cues in  29- 2
  "    as Sensitive Indicators of Aquatic Pollutant Toxicity to Crusta  38- 2
Gulf Toadfish (Cpsanus beta) and Results Using Chlorpyrifos /,Early Ld  23- 1
 11   Breeze Laboratory Titles and Abstracts: 1986, 1987, in Press and   17- 1
 "   of Mexico /,Lesions in Fishes Captured near Drilling Platforms in  22- 3
 11   Breeze, Florida /,0rganotin Toxicity Studies Conducted with Selec  46-3
 11   Breeze Laboratory /,Publications:                                  17- 2
 "   Breeze, Florida /,Results of Acute Toxicity Testing of Single Spe  43- 2
                                     H
Handbook of Chemicals to Estuarine Organisms /,Acute Toxicity           26-1
Hybridization in the Rapid Isolation of 4-Chlorobiphenyl Degradative B  35- 1
Hydrocarbon Metabolism in Fishes /,Polynuclear Aromatic                 44- 3
Hydrogen Sulfide /,Emersion in the Mangrove Forest Fish Rivulus marmor   1- 1
                                     I
Impact of Drilling Fluids on Seagrasses: An Experimental Community App  30- 2
Improved Silica Gel Cleanup Method for Organophosphorous Pesticides     25- 2
Indicators of Aquatic Pollutant Toxicity to Crustaceans /,Mblt-Related  38- 2
Information to Microcosms and Field Studies: A Summary of Research Res  36-3
Ingestion Rate /,Bioaccumulation of Kepone by Spot  (Leiostomus xanthur  18- 1
Inhibition of Arm Regeneration by Ophioderma brevispina (Echinodermata  46- 1
Inhibitors in Lake Water /,Bacterial                                    24- 2
Insecticide Fenthion on Mysidopsis bahia Exposed During a Complete Lif  27- 2
Insecticides /, Effects of Salinity Change on Acute Lethal Responses of   3- 1
Integration of Monitoring and Research in Coastal Waters: Issues for C  19- 1
Interface in Laboratory Systems /,Movement of Kepone  (Chlordecone) Acr  37-3
                                     J
Jet and Missile Fuels by Aquatic Microbial (Communities /,Degradation o  36-2
                                     K
Kepone by Spot (Leiostomus xanthurus): Importance of Dietary Accumulat  18- 1
  "    (Chlordecone) Across an Undisturbed Sediment-Water Interface in  37- 3
                                     L
Lagenidium giganteum) Under Development as an MPCA for Nontarget Risk   19- 2
Lake Water /,Bacterial Inhibitors in                                    24- 2
Larvae and Adults of the Estuarine Crab, Eurypanopeus depressus /,Infl  41-2
  "    at Different Salinities /,Laboratory Spawning Cues in Menidia b  29- 2
  11    in Toxicity Tests: Survival and Development When Exposed to Org  46- 2
Leiostomus xanthurus): Importance of Dietary Accumulation and Ingestip  18- 1
Lesions in Fishes Captured near Drilling Platforms in the Gulf of Mexi  22- 3
Lethal Responses of Bay Mysids (Mysidopsis bahia) to Three Insecticide   3- 1
Life-Stage Toxicity Test Methods for Gulf Toadfish  (Opsanus beta) and   23- 1
 "   Stage Exposures to Chlorpyrifos /,Effects of Diet Quantity on She  12- 1
 11   Cycle: I. Survival, Reproduction, and Age-Specific Growth /,Influ  27- 2
 11   Stages of Atherinid Fishes /,Methods for Spawning, Culturing and   29- 3
Limb Growth as Sensitive Indicators of Aquatic Pollutant Toxicity to C  38- 2
Lindane on Survival and Osmoregulatory/Metabolic Responses of the Larv  41- 2
Lugworm  (Arenicola cristata) Larvae in Toxicity Tests: Survival and De  46-2
                                     M
Macrofauna Colonizing Sediments Contaminated with Fenvalerate //Respon  43- 1
                                   PAGE  54

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     M
Mangrove Forest Fish Rivulus marmoratus: A Unique Response to Hydrogen   1- 1
Marine Prosobranchs from Northwest Florida /,Egg Capsules of Eleven     14- 2
  "    Prosobranchs from Florida and Bimini, Bahamas /, Laboratory Spaw  14- 3
  11    Crustacea /,Methods for Determining the Influence of Biochemica  28- 1
  11    Organisms at EPA's Environmental Research Laboratory, Gulf Bree  46- 3
marmoratus: A Unique Response to Hydrogen Sulfide /,Emersion in the Ma   1-1
    11       Laboratory and Field Observations /,Evidence for Embryonic  39- 1
    11      in Research on Aquatic Pollutants /,Role of Rivulus          15- 1
Membranes, and Egg Capsules of 14 Small Marine Prosobranchs from Flori  14- 3
Menidia beryllina and M. peninsulae (Pisces, Atherinidae) with Notes o  29- 2
Metabolic Responses of the larvae and Adults of the Estuarine Crab, Eu  41- 2
Metabolism of Trichloroethylene by a Bacterial Isolate /,Aerobic        31-2
    11      of Alachlor and Propachlor in Suspensions of Pretreated Soi  32- 1
    11      of Aromatic Compounds by Caulobacter crescentus               4- 3
    11      of Fenthion by Aquatic Microbial Communities                 37- 2
    11      in Fishes /,Polynuclear Aromatic Hydrocarbon                 44- 3
Metamorphosis of Marine Crustacea /,Methods for Determining the Influe  28- 1
Mexico /,Lesions in Fishes Captured near Drilling Platforms in the Gul  22- 3
Microbial ODmmunities /, Degradation of Jet and Missile Fuels by Aquati  36-2
    11     Communities /,Metabolism of Fenthion by Aquatic               37- 2
Microcosms and Field Studies: A Summary of Research Results /,Extrapol  36-3
Microorganisms Occurring in Natural Aquatic Environments /,Evidence fo   9- 1
Minnows  (Cyprinodon variegatus) During Early Life-Stage Exposures to C  12- 1
   "    Exposed to Fenthion /,Field and Laboratory Toxicity Tests with   7- 1
Missile Fuels by Aquatic Microbial Communities /,Degradation of Jet an  36-2
Modification of Microorganisms Occurring in Natural Aquatic Environmen   9- 1
Molt-Related Susceptibility and Regenerative Limb Growth as Sensitive   38-2
Movement of Kepone (Chlordecone) Across an Undisturbed Sediment-Water   37- 3
MPCA for Nontarget Risk /,Evaluation of a Fungal Agent (lagenidium gig  19- 2
Multi-Species Laboratory Test Systems for Estuarine Benthic Communitie  16- 1
Mysidopsis bahia) to Three Insecticides /,Effects of Salinity Change o   3-1
    11      bahia Exposed During a Complete Life Cycle: I. Survival, Re  27- 2
    11      bahia) /,Toxicity of Used Drilling Fluids to Mysids (        21- 1
Mysids (Mysidopsis bahia) to Three Insecticides /,Effects of Salinity    3- 1
  11     and Sheepshead Minnows Exposed to Fenthion /,Field and Laborat   7- 1
  "    (Mysidopsis bahia) /,Toxicity of Used Drilling Fluids to         21-1
                                     N
Nontarget Risk /,Evaluation of a Fungal Agent (Lagenidium giganteum) U  19- 2
                                     0
Ophioderma brevispina (Echinodermata, Ophiuroidea) by Tributyltin Oxid  46-1
Ophiuroidea) by Tributyltin Oxide and Triphenyltin Oxide /, Inhibit ion   46-1
Opsanus beta) and Results Using Chlorpyrifos /,Early Life-Stage Toxici  23- 1
Organic Chemicals to Grass Shrimp (Palaemonetes pugio) and Amphioxus (   8- 2
Organisms /,Acute Toxicity Handbook of Chemicals to Estuarine           26-1
    11     at EPA's Environmental Research Laboratory, Gulf Breeze, Flo  46- 3
Organophosphate Insecticide Fenthion on Mysidopsis bahia Exposed Durin  27- 2
Organophosphorous Pesticides /,Improved Silica Gel Cleanup Method for   25- 2
Organotin Toxicity Studies Conducted with Selected Marine Organisms at  46-3
Organotins /,Lugworm (Arenicola cristata) Larvae in Toxicity Tests: Su  46-2
Osmoregulatory/Metabolic Responses of the larvae and Adults of the Est  41- 2
Oxide /,Inhibition of Arm Regeneration by Ophioderma brevispina (Echin  46- 1
  11   and Triphenyltin Oxide /,Inhibition of Arm Regeneration by Ophio  46-1
                                     P
Palaemonetes pugio) and Amphioxus (Branchiostoma caribaeum) /,Waterbor   8- 2
Pathway /,Biodegradation of Trichloroethylene and the Involvement of a  31-3
PCBs by Fiddler Crabs /Accumulation of Sediment-Bound                   5- 1
peninsulae (Pisces, Atherinidae) with Notes on Survival and Growth of   29- 2
Pesticides /,Improved Silica Gel Cleanup Method for Organophosphorous   25- 2
                                   PAGE  55

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     P
Phenotypes /,Use of DNA:DNA Colony Hybridization in the Rapid Isolatio  35-1
Phthalate-C&ntaminated Sediment to laboratory- and Field-Colonized Est  44- 2
Pisces, Atherinidae) with Notes on Survival and Growth of larvae at Di  29-2
Plankton in Aquatic Toxicity Testing /,Use of                           48- 1
Platforms in the Gulf of Mexico /,Lesions in Fishes Captured near Dril  22- 3
Point of View /,Integration of Monitoring and Research in Coastal Wate  19- 1
Pollutant Toxicity to Crustaceans /,Molt-Related Susceptibility and Re  38- 2
Pollutants /,Fate of                                                    37- 1
    "      /,Role of Rivulus marmoratus in Research on Aquatic          15- 1
Polynuclear Aromatic Hydrocarbon Metabolism in Fishes                   44- 3
Populations of Crustacea to Toxicants /,Critical Responses of           27-1
Preparation Publications /,Gulf Breeze Laboratory Titles and Abstracts  17- 1
Press and in Preparation Publications /,Gulf Breeze Laboratory Titles   17- 1
Pretreated Soils and in Samples from Ground Water Aquifers /,Metabolis  32- 1
Probe /,Chitinase Determinants of Vibrio vulnificus: Gene Cloning and   49- 2
Propachlor in Suspensions of Pretreated Soils and in Samples from Grou  32-1
Prosobranchs from Northwest Florida /,Egg Capsules of Eleven Marine     14- 2
     11       from Florida and Bimini, Bahamas /,Laboratory Spawning, E  14- 3
pugio) and Amphioxus (Branchiostoma caribaeum) /,Waterborne and Sedime   8- 2
                                     Q
Quantity on Sheepshead Minnows (Cyprinodon variegatus) Duriiig Early Li  12- 1
                                     R
Regeneration by Cphioderma brevispina (Echinodermata, Ophiuroidea) by   46- 1
Regenerative Lamb Growth as Sensitive Indicators of Aquatic Pollutant   38- 2
Regulatory Point of View /,Integration of Monitoring and Research in C  19- 1
Reproduction, and Age-Specific Growth /,Influence of the Organophospha  27- 2
Response to Hydrogen Sulfide /,Emersion in the Mangrove Forest Fish Ri   1-1
Responses of Caged Estuarine Animals Exposed to Fenthion in the Field    5- 2
    11     of Populations of Crustacea to Toxicants /,Critical           27- 1
    "     of Bay Mysids (Mysidopsis bahia) to Three Insecticides /,Eff   3- 1
    11     of the Larvae and Adults of the Estuarine Crab, Eurypanopeus  41- 2
    11     of Estuarine Macrofauna Colonizing Sediments Contaminated wi  43-1
Risk Assessment Research /,Biotechnology Aquatic                         3-2
 "   /,Evaluation of a Fungal Agent  (Lagenidium giganteum) Under Devel  19- 2
Rivulus marmoratus: A Unique Response to Hydrogen Sulfide /,Emersion i   1-1
   "    marmoratus: Laboratory and Field Observations /,Evidence for E  39- 1
   "    marmoratus in Research on Aquatic Pollutants /,Role of          15- 1
                                     s
Salinities /,Laboratory Spawning Cues in Menidia beryllina and M. peni  29- 2
Salinity Change on Acute Lethal Responses of Bay Mysids (Mysidopsis ba   3-1
Seagrasses: An Experimental Community Approach /,Impact of Drilling Fl  30- 2
Sediment-Bound PCBs by Fiddler Crabs /,Accumulation of                   5- 1
   "     Water Interface in Laboratory Systems /,Movement of Kepone (C  37- 3
   11     Associated Chemicals /,Techniques for Study of Effects and Up  47- 3
   11     to Laboratory- and Field-Colonized Estuarine Benthic Communit  44- 2
   "     Source Toxicities of Six Organic Chemicals to Grass Shrimp (P   8- 2
Sediments Contaminated with Fenvalerate /,Responses of Estuarine Macro  43-1
Sensitive Indicators of Aquatic Pollutant Toxicity to Crustaceans /,Mo  38-2
Sheepshead Minnows  (Cyprinodon variegatus) During Early Life-Stage Exp  12- 1
    11      Minnows Exposed to Fenthion /,Field and Laboratory Toxicity   7- 1
Shrimp, Mysids, and Sheepshead Minnows Exposed to Fenthion /,Field and   7- 1
  "    (Palaemonetes pugio) and Amphioxus (Branchiostoma caribaeum) /,   8-2
Silica Gel Cleanup Method for Organophosphorous Pesticides /,Improved   25- 2
Soils and in Samples from Ground Water Aquifers /,Metabolism of Alachl  32- 1
Source Toxicities of Six Organic Chemicals to Grass Shrimp (Palaemonet   8- 2
Spawning Cues in Menidia beryllina and M. peninsulae  (Pisces, Atherini  29- 2
   11      Egg Membranes, and Egg Capsules of 14 Small Marine Prose-bran  14- 3

                                   PAGE  56

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     S
Spawning, Culturing and Conducting Toxicity Tests with Early Life Stag  29- 3
Spot  (Leiostomus xanthurus): Importance of Dietary Accumulation and In  18- 1
Sulfide /,Emersion in the Mangrove Forest Fish Rivulus marmoratus: A U   1-1
Survival and Osmoregulatory/Metabolic Responses of the Larvae and Adul  41-2
   11      Reproduction, and Age-Specific Growth /,Influence of the Org  27- 2
   11     and Growth of Larvae at Different Salinities /, Laboratory Spa  29- 2
   11     and Development When Exposed to Organotins /,Lugworm (Arenico  46- 2
   11     to Other Endpoints in Chronic Toxicity Tests with Fish /,Rela  26-2
Susceptibility and Regenerative Limb Growth as Sensitive Indicators of  38- 2
Suspensions of Pretreated Soils and in Samples from Ground Water Aquif  32- 1
                                     T
Techniques for Study of Effects and Uptake of Sediment-Associated Chem  47- 3
Test Results with Responses of Caged Estuarine Animals Exposed to Fent   5- 2
 11   Methods for Gulf Toadfish (Opsanus beta) and Results Using Chlorp  23- 1
 11   Systems for Estuarine  Benthic Communities /,Field Validation of M  16- 1
Testing of Single Species Dominant in Benthic Community Testing at Gul  43- 2
   11    at Gulf Breeze, Florida /,Results of Acute Toxicity Testing of  43- 2
   "    /,Use of Plankton in Aquatic Toxicity                           48- 1
Tests with Shrimp, Mysids,  and Sheepshead Minnows Exposed to Fenthion    7- 1
  11    Survival and Development When Exposed to Organotins /,Lugworm (  46-2
  "   with Early Life Stages of Atherinid Fishes /,Methods for Spawnin  29- 3
  "   with Fish /,Relation  of Survival to Other Endpoints in Chronic T  26-2
testudinum and Its Epiphytic Algae /,Effects of Drilling Fluids on Tha  35- 2
Thalassia testudinum and Its Epiphytic Algae /,Effects of Drilling Flu  35-2
Titles and Abstracts: 1986, 1987, in Press and in Preparation Publicat  17- 1
Toadfish  (Opsanus beta) and Results Using Chlorpyrifos /,Early Life-St  23- 1
Toxicants /,Critical Responses of Populations of Crustacea to           27- 1
    11     on Laboratory- and Field-Colonized Estuarine Benthic Communi  44- 1
Toxicities of Six Organic Chemicals to Grass Shrimp (Palaemonetes pugi   8- 2
Toxicity Handbook of Chemicals to Estuarine Organisms /,Acute           26-1
   11     Test Results with  Responses of Caged Estuarine Animals Expose   5- 2
   11     Test Methods for Gulf Toadfish (Opsanus beta) and Results Usi  23- 1
   "     Tests with Shrimp, Mysids, and Sheepshead Minnows Exposed to    7-1
   11     Tests: Survival and Development When Exposed to Organotins /,  46- 2
   "     Tests with Early Life Stages of Atherinid Fishes /, Methods fo  29- 3
   11     to Crustaceans /,Molt-Related Susceptibility and Regenerative  38- 2
   11     Studies Conducted  with Selected Marine Organisms at EPA's Env  46-3
   "     Tests with Fish /,Relation of Survival to Other Endpoints in   26-2
   "     Testing of Single  Species Dominant in Benthic Community Testi  43- 2
   "     of Dibutyl Phthalate-Contaminated Sediment to Laboratory- and  44- 2
   11     of Used Drilling Fluids to Mysids (Mysidopsis bahia)           21-1
   11     Testing /,Use of Plankton in Aquatic                           48- 1
Tributyltin Oxide and Triphenyltin Oxide /,Inhibition of Arm Regenerat  46-1
Trichloroethylene /,Aerobic Biodegradation of                           31- 1
        11         by a Bacterial Isolate /,Aerobic Metabolism of        31- 2
        11         and the Involvement of an Aromatic Biodegradative Pa  31-3
Triphenyltin Oxide /,Inhibition of Arm Regeneration by Ophioderma brev  46-1
                                     U
Undisturbed Sediment-Water  Interface in Laboratory Systems /,Movement   37- 3
Unique Response to Hydrogen Sulfide /,Emersion in the Mangrove Forest    1- 1
Uptake of Sediment-Associated Chemicals /,Techniques for Study of Effe  47- 3
                                     V
Validation of Multi-Species Laboratory Test Systems for Estuarine Bent  16- 1
variegatus) During Early Life-Stage Exposures to Chlorpyrifos /,Effect  12- 1
Vibrio vulnificus: Gene Cloning and Applications of a Chitinase Probe   49- 2
View /,Integration of Monitoring and Research in Coastal Waters: Issue  19- 1
vulnificus: Gene Cloning and Applications of a Chitinase Probe /,Chiti  49- 2
                                     W
Water /,Bacterial Inhibitors in Lake                                    24- 2
                                   PAGE  57

-------
                            KEYWORD TITLE INDEX                         P   I
                                                                        A   T
                                                                        G   E
                                                                        E   M
                                     W
Water Aquifers /,Metabolism of Alachlor and Propachlor in Suspensions   32- 1
  "   Interface in laboratory Systems /,Movement of Kepone (Chlordecon  37- 3
Waterborne and Sediment-Source Toxicities of Six Organic Chemicals to    8- 2
Waters: Issues for Consideration from a Regulatory Point of View /,Int  19-1
                                     X
xanthurus): Importance of Dietary Accumulation and Ingestion Rate /,Bi  18- 1
                                   PAGE  58

-------
AUTHOR INDEX
    PAGE  59

-------
                               AUTHOR INDEX
                                     A
Abel, Daniel C.
  Emersion in the Mangrove Forest Fish Rivulus marmoratus: A Unique Response
  to Hydrogen Sulfide/,1-1

Ahearn, Donald G.
  Fungi and Hydrocarbons in the Marine Environment/,1-2

Ahearn, Donald G., Joint Author.
  Movement of Kepone (Chlordecone) Across an Undisturbed Sediment-Water
  Interface in laboratory Systems/,37-3

  Physical and Biological Parameters That Determine the Fate of p-Chlorqphenol
  in Laboratory Test Systems/,38-1

Alexander, Martin
  Anomalous Effects of Concentration on Biodegradation of Organic
  Chemicals/, 1-3

Alexander, Martin, Joint Author.
  Bacterial Inhibitors in Lake Water/,24-2

  Biodegradation by Mineralization or Cometabolism Determined by Chemical
  Concentration and Environment/,48-2

  Effect of Bacterial Growth on Protozoan Predation in the Presence of
  Alternative Prey/,42-1

  Metabolism of Alachlor and Propachlor in Suspensions of Pretreated Soils and
  in Samples from Ground Water Aquifers/,32-1

                                     B
Barkay, Tamar
  Adaptation of Aquatic Microbial Communities to Hg2+ Stress/,2-1

  Bacteria and the Environment/,2-2

  Gene Probes as a Tool for the Detection of Specific Genomes in the
  Environment/,2-3

Barkay, Tamar, Joint Author.
  Gene Transfer Among Bacteria in Soil and Aquatic Environments: A
  Review/,45-1

  Genetic Stability of Plasmid DNA in Aquatic Bacteria/,21-2

Biggs, Robert B., Joint Author.
  Characterizing the Chesapeake Bay Ecosystem and Lessons Learned/, 18-2

Blackburn, James, Joint Author.
  Applications for DNA Probes in Biodegradation Research/,40-2

Borthwick, Patrick W.
  Effects of Salinity Change on Acute Lethal Responses of Bay Mysids
  (Mysidqpsis bahia) to Three Insecticides/,3-1

Borthwick, Patrick W., Joint Author.
  Comparison of laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

                                   PAGE  60

-------
                               AUTHOR INDEX
                                     B
Borthwick, Patrick W., Joint Author.
  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shriirp,
  Mysids, and Sheepshead Minnows/,6-1

  Field and Laboratory Toxicity Tests with Shrimp, Mysids, and Sheepshead
  Minnows Exposed to Fenthion/,7-1

Bourquin, Al W.
  Biotechnology Aquatic Risk Assessment Research/,3-2

Bourquin, Al W., Joint Author.
  Aerobic Biodegradation of Trichloroethylene/,31-1

  Bacteria and the Environment/,2-2

  Biological and Abiotic Degradation Rates of Xenobiotic Chemicals in In Vitro
  Estuarine and Sediment/Water Systems/,45-2

  Biotic and Abiotic Degradation Rates of Methyl Parathion in Freshwater and
  Estuarine Water and Sediment Samples/,3 6-1

  Degradation of Jet and Missile Fuels by Aquatic Microbial Cornmunities/,36-2

  Gene Transfer Among Bacteria in Soil and Aquatic Environments: A
  Review/,45-1

  Genetic Stability of Plasmid DNA in Aquatic Bacteria/,21-2

  Metabolism of Aromatic Compounds by Caulobacter crescentus/,4-3

  Shake-Flask Test for Estimation of Biodegradability of Toxic Organic
  Substances in the Aquatic Environment/,14-1

Brayton, P.R.
  Fluorescent Antibody Staining Method for Enumeration of Viable Environmental
  Vibrio cholerae/,3-3

Brusca, J.
  Autographa californica Nuclear Polyhedrosis Virus Efficiently Enters but
  Does Not Replicate in Polikilo Thermic Vertebrate Cells/,4-1

                                     C
Capuzzo, Judith M.
  Development of Physiological Indices to Predict the Effects of Chronic
  Pesticide Exposure on Zooplankton Populations/,4-2

Chatterjee, Deb K.
  Metabolism of Aromatic Compounds by Caulobacter crescentus/,4-3

Chatterjee, Deb K., Joint Author.
  Bacteria and the Environment/,2-2

Chatterjee, Pramita, Joint Author.
  Genetic Stability of Plasmid DNA in Aquatic Bacteria/,21-2

Clark, James R.
  Accumulation of Sediment-Bound PCBs by Fiddler Crabs/,5-1
                                   PAGE  61

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                               AUTHOR INDEX
                                     C
Clark, James R.
  Comparison of Laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shriirp,
  Mysids, and Sheepshead Minnows/,6-1

  Field and laboratory Toxicity Tests with Shrimp,  Mysids,  and Sheepshead
  Minnows Exposed to Fenthion//7-1

  Toxicity of Sediment-Incorporated Drilling Fluids to Lancelets
  (Branchiostoma caribaeum)/,8-l

  Waterborne and Sediment-Source Toxicities of Six Organic Chemicals to Grass
  Shrimp (Palaemonetes pugio)  and Amphioxus (Branchiostoma caribaeum)/,8-2

Clark, James R., Joint Author.
  Bioaccuraulation of Kepone by Spot (Leiostomus xanthurus) : Importance of
  Dietary Accumulation and Ingestion Rate/,18-1

  Effects of Drilling Fluids on Thalassia testudinum and Its Epiphytic
  Algae/,35-2

  Impact of Drilling Fluids on Seagrasses: An Experimental Community
  Approach/,30-2

Cleveland, Mary E., Joint Author.
  Validity of Partition Coefficient as the Adsorption Descriptor in Exposure
  Concentrations Predictions:  Studies with Kepone and Methyl Parathion/,10-l

Colwell, Rita R.
  Evidence for Genetic Modification of Microorganisms Occurring in Natural
  Aquatic Environments/,9-1

  Release of Genetically Engineered Microorganisms into the Environment/,9-2

Colwell, Rita R., Joint Author.
  Application of Ion-Exchange High-Performance Liquid Cnromatography in the
  Purification of 5S rRNAs Suitable for Sequence Analysis/,25-3

  Chitinase Determinants of Vibrio vulnificus: Gene Cloning and Applications
  of a Chitinase Probe/,49-2

  Distribution of Mutations in Gram Negative Eubacterial 5S rRNAs and
  Significance for Sequence Analysis/,25-4

  Fluorescent Antibody Staining Method for Enumeration of Viable Environmental
  Vibrio cholerae/,3-3

  Plasmid Mobility in the Ocean Environment/,22-2

  Rapid Indirect Test for Chitinase Activity Using
  4-Methylumbellif eryl-N-Acetyl-B-D-Glucosaminide/ ,32-2

Conklin, Philip J., Joint Author.
  Molt-Related Susceptibility and Regenerative Limb Growth as Sensitive
  Indicators of Aquatic Pollutant Toxicity to Crustaceans/,38-2
                                   PAGE  62

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                               AUTHOR INDEX
                                     C
Connolly, John P.
  Validity of Partition Coefficient as the Adsorption Descriptor in Exposure
  Concentrations Predictions: Studies with Kepone and Methyl Parathion/,10-1

Connolly, John P., Joint Author.
  Bioaccumlation of Kepone by Spot (Leiostoraus xanthurus): Importance of
  Dietary Accumulation and Ingestion Rate/,18-1

  Movement of Kepone (Chlordecone) Across an Undisturbed Sediment-Water
  Interface in Laboratory Systems/,37-3

Couch, John A.
  Carcinogenicity Tests: Utilization of Ectothermic Organisms/, 10-2

  DENA-Induced Hepatocarcinogenesis in the Estuarine Sheepshead Minnow
  (Cyprinodon variegatus): Neoplasms and Related Lesions with Comparisons to
  Mammalian Lesions/,11-1

  Enclosed Systems for Testing Microbial Pest Control Agents/,11-2

Couch, John A., Joint Author.
  Autographa californica Nuclear Polyhedrosis Virus Efficiently Enters but
  Does Not Replicate in Polikilo Thermic Vertebrate Cells/,4-1

  Cytological Changes During Progression of Neoplasia/,23-2

  Evaluation of a Fungal Agent  (Lagenidium giganteum) Under Development as an
  MPCA for Nontarget Risk/,19-2

  Proctoeces sp. (Trematoda: Digenea) in Australian Oysters, Saccostrea
  commercialis and Crassostrea amasa/,49-1

Courtney, Lee A., Joint Author.
  Autographa californica Nuclear Polyhedrosis Virus Efficiently Enters but
  Does Not Replicate in Polikilo Thermic Vertebrate Cells/,4-1

  Cytological Changes During Progression of Neoplasia/,23-2

  DENA-Induced Hepatocarcinogenesis in the Estuarine Sheepshead Minnow
  (Cyprinodon variegatus): Neoplasms and Related Lesions with Comparisons to
  Mammalian Lesions/,11-1

  Evaluation of a Fungal Agent  (Lagenidium giganteum) Under Development as an
  MPCA for Nontarget Risk//19-2

Gripe, Claude R.
  Fate of Fenthion in Salt-Marsh Environments: l. Factors Affecting Biotic and
  Abiotic Degradation Rates in Water and Sediment/,13-1

  Shake-Flask Test for Estimation of Biodegradability of Toxic Organic
  Substances in the Aquatic Environment/,14-1

Cripe, Claude R., Joint Author.
  Biological and Abiotic Degradation Rates of Xenobiotic Chemicals in In Vitro
  Estuarine and Sediment/Water Systems/,45-2

  Biotic and Abiotic Degradation Rates of Methyl Parathion in Freshwater and
  Estuarine Water and Sediment Samples/,36-1

                                   PAGE  63

-------
                               AUTHOR INDEX
                                     C
Gripe, Claude R., Joint Author.
  Metabolism of Fenthion by Aquatic Microbial Communities/,37-2

Gripe, Geraldine M.
  Effects of Diet Quantity on Sheepshead Minnows (Cyprinodon variegatus)
  During Early Life-Stage Exposures to Chlorpyrifos/,12-1

  Occurrence of Mysidopsis bahia (Mysidacea,Mysidae) on the Atlantic Coast of
  Florida/,13-2

Gripe, Geraldine M., Joint Author.
  Acute Tbxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride
  to Mysids (Mysidopsis bahia) of Three Different Ages/,21-3

  Cage for Use with Small Aquatic Animals in Field Studies/,22-1

  Early Life-Stage Toxicity Test Methods for Gulf Toadfish (Opsanus beta) and
  Results Using Chlorpyrifos/,23-1

Crow, S.A., Joint Author.
  Fungi and Hydrocarbons in the Marine Environment/,1-2

Cuskey, S., Joint Author.
  Bacteria and the Environment/,2-2

                                     D
D'Asaro, Charles N.
  Egg Capsules of Eleven Marine Prosobranchs from Northwest Florida/,14-2

  Laboratory Spawning, Egg Membranes, and Egg Capsules of 14 Small Marine
  Prosobranchs from Florida and Bimini, Bahamas/,14-3

Davis, William P.
  Role of Rivulus marmoratus in Research on Aquatic Pollutants/,15-1

Davis, William P., Joint Author.
  Emersion in the Mangrove Forest Fish Rivulus marmoratus: A Unique Response
  to Hydrogen Sulfide/,1-1

  Evidence for Embryonic Diapause in Rivulus marmoratus: Laboratory and Field
  Observations/,39-1

DeWeerd, Kim A.
  Relationship Between Reductive Dehalogenation and Other Aryl Substituent
  Removal Reactions Catalyzed by Anaerobes/,15-2

Deans, Christine H., Joint Author.
  Comparison of Four Methods for Calculating the EC50 from Algal Population
  Growth/,45-3

  Inhibition of Arm Regeneration by Ophioderma brevispina (Echinodermata,
  Ophiuroidea) by Tributyltin Oxide and Triphenyltin Oxide/,,46-1

  Responses of Estuarine Macrofauna Colonizing Sediments Contaminated with
  Fenvalerate/,43-1

  Toxicity of Dibutyl Phthalate-Contaminated Sediment to Laboratory- and
  Field-Colonized Estuarine Benthic Communities/,44-2

                                   PAGE  64

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                               AUTHOR INDEX
                                     D
Diaz, Robert J.
  Field Validation of Multi-Species Laboratory Test Systems for Estuarine
  Benthic Ocraraunities/,16-1

Dickson, K.L. , Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

Duke, Thomas W.
  Drilling Fluid Test Procedure: Participation, Data Comparison and
  Implementation/, 16-2

  Toxic Effects on Individuals, Populations and Aquatic Ecosystems and
  Indicators of Exposure to Chemicals/,16-3

Duke, Thomas W. , Joint Author.
  Ecosystem Perspective on Potential Impacts of Drilling Fluid Discharges on
  Seagrasses/ , 24-1

  Effects of Drilling Fluids on Marine Organisms/,34-1

  Impact of Drilling Fluids on Seagrasses: An Experimental Oommunity
  Approach/ , 30-2

  Integration of Monitoring and Research in Coastal Waters: Issues for
  Consideration from a Regulatory Point of View/ ,19-1

  Toxicity of Used Drilling Fluids to Mysids (Mysidopsis bahia)/,21-l

  Variability of the Acute Toxicity of Drilling Fluids to Mysids (Mysidopsis
  bahia)/,34-2

                                     E
Ellersieck, Mark R. , Joint Author.
  Relation of Survival to Other Endpoints in Chronic Toxicity Tests with
  Fish// 26-2

Environmental Research Laboratory, Gulf Breeze, FL
  Gulf Breeze Laboratory Titles and Abstracts:  1986, 1987, in Press and in
  Preparation Publications/,17-1

  Publications:  Gulf Breeze Laboratory/ , 17-2

                                     F
Federle, Thomas W.
  Quantitative Co
  Sediments from Microcosms and the Field/,17-3
  Quantitative Comparison of Microbial Community Structure of Estuarine
               m Micr
Fisher, Daniel J.
  Bioaccumulation of Kepone by Spot (Leiostomus xanthurus) :  Importance of
  Dietary Accumulation and Ingestion Rate/,18-1

Flemer, David A.
  Characterizing the Chesapeake Bay Ecosystem and Lessons Learned/,18-2

  Integration of Monitoring and Research in Coastal Waters:  Issues for
  Consideration from a Regulatory Point of View/,19-1
                                   PAGE  65

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                               AUTHOR INDEX
                                     F
Forester, Jerrold, Joint Author.
  Accumulation of Sediment-Bound PCBs by Fiddler Crabs/,5-1

  Effects of Diet Quantity on Sheepshead Minnows (Cyprinodon variegatus)
  During Early Life-Stage Exposures to Chlorpyrifos/,12-1

Foss, Steven S.
  Evaluation of a Fungal Agent  (Lagenidium giganteum)  Under Development as an
  MPCA for Nontarget Risk//19-2

Fredrickson, Herbert L.
  Microbial 14CO2 Release and Lipid Biosynthesis from Acetate, Lactate and
  Glucose in a Spartina Rhizosphere and a Nonvegetated Tidal Flat/,20-1

                                     G
Gaetz, Charles T.
  Laboratory Culture and Observations on the Reproductive Biology of the
  Marine Pelagic Isopod, Idotea metallica (Crustacea;  Isopoda)/,20-2

  Toxicity of Used Drilling Fluids to Mysids (Mysidopsis bahia)/,21-l

Genthner, F., Joint Author.
  Bacteria and the Environment/,2-2

Genthner, Fred J.
  Genetic Stability of Plasmid DNA in Aquatic Bacteria/,21-2

Gillian, W.T., Joint Author.
  Fate of Fenthion in Salt-Marsh Environments: 1. Factors Affecting Biotic and
  Abiotic Degradation Rates in Water and Sediment/,13-1

Goodman, Larry R.
  Acute Toxicity of Malathion, Tetrabrbmobisphenol-A,  and Tributyltin Chloride
  to Mysids (Mysidopsis bahia) of Three Different Ages/,21-3

  Cage for Use with Small Aquatic Animals in Field Studies/,22-1

Goodman, Larry R., Joint Author.
  Comparison of laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

  Early Life-Stage Toxicity Test Methods for Gulf Toadfish (Opsanus beta) and
  Results Using Chlorpyrifos/,23-1

  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shrimp,
  Mysids, and Sheepshead Minnows/,6-1

  Field and Laboratory Toxicity Tests with Shrimp, Mysids, and Sheepshead
  Minnows Exposed to Fenthion/,7-1

  Methods for Spawning, Culturing and Conducting Toxicity Tests with Early
  life Stages of Atherinid Fishes/,29-3

Grimes, D.J.
  Plasmid Mobility in the Ocean Environment/,22-2

Grimes, D.J., Joint Author.
  Evidence for Genetic Modification of Microorganisms Occurring in Natural
  Aquatic Environments/,9-1

                                   PAGE  66

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                               AUTHOR INDEX
                                     G
Grizzle, John M.
  Lesions in Fishes Captured near Drilling Platforms in the Gulf of
  Mexico/,22-3

Gustin, Denise, Joint Author.
  DNA Sorption to Soils and Sediments/,33-1

                                     H
Halsell, Darrel G., Joint Author.
  Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride
  to Mysids (Mysidopsis bahia) of Three Different Ages/,21-3

Hamelink, J.L., Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

Hansen, David J.
  Early Life-Stage Toxicity Test Methods for Gulf Toadfish (Opsanus beta) and
  Results Using Chlorpyrifos/,23-1

Hansen, David J., Joint Author.
  Effects of Diet Quantity on Sheepshead Minnows (Cyprinodon variegatus)
  During Early Life-Stage Exposures to Chlorpyrifos/,12-1

Harwell, Christine C., Joint Author.
  Ecosystem Perspective on Potential Impacts of Drilling Fluid Discharges on
  Seagrasses/,24-1

Harwell, Mark A., Joint Author.
  Ecosystem Perspective on Potential Impacts of Drilling Fluid Discharges on
  Seagrasses/,24-1

Hemmer, Michael J., Joint Author.
  Embryo Ecology of the Pacific Surf Smelt, Hypomesus pretiosus (Pisces:
  Osmeridae)/,28-3

  Influence of Environmental Temperature on Sex-ratios in the Tidewater
  Silverside, Menidia peninsulae/,29-1

  Laboratory Spawning Cues in Menidia beryllina and M. peninsulae (Pisces,
  Atherinidae) with Notes on Survival and Growth of Larvae at Different
  Salinities/,29-2

  Methods for Spawning, Culturing and Conducting Toxicity Tests with Early
  Life Stages of Atherinid Fishes/,29-3

  Reproductive Ecology of the Tidewater Silverside, Menidia peninsulae
  (Pisces: Atherinidae) from Santa Rosa Island, Florida/,30-1

  Reproductive Rhythmicity of the False Grunion, Colpichthys regis,  from
  Estero del Soldado, Mexico/,39-2

Hendricks, S.J., Joint Author.
  Impact of Drilling Fluids on Seagrasses: An Experimental Community
  Approach/,30-2

Hinton, David E.
  Cytological Changes During Progression of Neoplasia/,23-2
                                   PAGE  67

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                               AUTHOR INDEX
                                     H
Houston, Laura, Joint Author.
  Applications for ENA Probes in Biodegradation Research//40-2

                                     J
Jain, Rakesh K., Joint Author.
  Applications for ENA Probes in Biodegradation Research/,40-2

                                     K
Kelly, John R.
  Ecosystem Perspective on Potential Impacts of Drilling Fluid Discharges on
  Seagrasses/,24-1

Kimerle, R.A., Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

KLein, Theodore M.
  Bacterial Inhibitors in Lake Water/,24-2
                                                                 ^
Koenig, Christopher C., Joint Author.                           - v *
  Emersion in the Mangrove Forest Fish Rivulus marmoratus: A Unii&e Response
  to Hydrogen Sulfide/,1-1

  Field Validation of Multi-Species laboratory Test Systems for Estuarine
  Benthic Communities/,16-1

Kokjohn, Tyler A.
  Characterization of recA Mutants of Pseudomonas aeruginosa: rec-102 is a
  Mutant Allele of the Pseudomonas aeruginosa PAD recA Gene/,24-3

  Characterization of the Pseudomonas aeruginosa PAO recA Analogue and
  Identification of Its Protein Product/,25-1

                                     L
Lamadrid-Rose, Yara, Joint Author.
  laboratory Spawning Cues in Menidia beryllina and M. peninsulae (Pisces,
  Atherinidae) with Notes on Survival and Growth of Larvae at Different
  Salinities/,29-2

Last, G.A., Joint Author.
  Distribution of Mutations in Gram Negative Eubacterial 5S rRNAs and
  Significance for Sequence Analysis/,25-4

Lech, J.J., Joint Author.
  Combined Use of Biochemical Indicators to Assess Sublethal Pollution Effects
  on Fundulus grandis, the Gulf Killifish/,41-1

Lewis, Russell L., Joint Author.
  DNA Sorption to Soils and Sediments/,33-1

Linkfield, Tim, Joint Author.
  Relationship Between Reductive Dehalogenation and Other Aryl Substituent
  Removal Reactions Catalyzed by Anaerobes/,15-2

Livingston, Robert J., Joint Author.
  Field Validation of Multi-Species Laboratory Test Systems for Estuarine
  Benthic C!ommunities/,16-l
                                   PAGE  68

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                               AUTHOR INDEX
                                     L
Livingston, Robert J., Joint Author.
  Quantitative Comparison of Microbial Community Structure of Estuarine
  Sediments from Microcosms and the Field/,17-3

Lores, Emile M.
  Improved Silica Gel Cleanup Method for Organophosphorous Pesticides/,25-2

lores, Emile M., Joint Author.
  Comparison of Laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shrimp,
  Mysids, and Sheepshead Minnows/,6-1

  Field and Laboratory Toxicity Tests with Shrimp, Mysids, and Sheepshead
  Minnows Exposed to Fenthion/,7-1

  Inhibition of Arm Regeneration by Qphioderma breyispina (Echinodermata,
  Ophiuroidea) by Tributyltin Oxide and Triphenyltin Oxide/,46-1

  Lugworm  (Arenicola cristata) Larvae in Toxicity Tests: Survival and
  Development When Exposed to Organotins/,46-2

  Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six
  Growth Media/, 47-2

  Waterborne and Sediment-Source Toxicities of Six Organic Chemicals to Grass
  Shrimp (Palaemonetes pugio) and Amphioxus (Branchiostoma caribaeum)/,8-2

Louie, Michael K., Joint Author.
  Inhibition of Arm Regeneration by Ophioderma brevispina (Echinodermata,
  Ophiuroidea) by Tributyltin Oxide and Triphenyltin Oxide/,46-1

  Lugworm  (Arenicola cristata) Larvae in Toxicity Tests: Survival and
  Development When Exposed to Organotins/,46-2

Luckenbach, M., Joint Author.
  Field Validation of Multi-Species Laboratory Test Systems for Estuarine
  Benthic Communities/,16-1

                                     M
MacDonell, M.T.
  Application of Ion-Exchange High-Performance Liquid Chromatography in the
  Purification of 5S rENAs Suitable for Sequence Analysis/,25-3

  Distribution of Mutations in Gram Negative Eubacterial 5S rRNAs and
  Significance for Sequence Analysis/,25-4

MacDonell, M.T., Joint Author.
  Plasmid Mobility in the Ocean Environment/,22-2

Macauley, John M., Joint Author.
  Effects of Drilling Fluids on Thalassia testudinum and Its Epiphytic
  Algae/,35-2

  Impact of Drilling Fluids on Seagrasses: An Experimental Oammunity
  Approach//30-2
                                   PAGE  69

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                               AUTHOR INDEX
                                     M
Macauley, Stephanie F., Joint Author.
  Early Life-Stage Toxicity Test Methods for Gulf Toadfish (Opsanus beta) and
  Results Using Chlorpyrifos/,23-1

  Effects of Diet Quantity on Sheepshead Minnows (Cyprinodon variegatus)
  During Early Life-Stage Exposures to Chlorpyrifos/,12-1

Macek, D.J., Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

Mackieman, Gail B., Joint Author.
  Characterizing the Chesapeake Bay Ecosystem and Lessons learned/, 18-2

Madsen, Eugene L., Joint Author.
  Biodegradation by Mineralization or Cometabolism Determined by Chemical
  Concentration and Environment/,48-2

Mahaffey, William R., Joint Author.
  Biodegradation of Trichloroethylene and the Involvement of an Aromatic
  Biodegradative Pathway/,31-3

Mayer, Foster L., Jr.
  Acute Toxicity Handbook of Chemicals to Estuarine Organisms/,26-1

  Relation of Survival to Other Endpoints in Chronic Toxicity Tests with
  Fish/,26-2

Mayer, Foster L., Jr., Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

  Integration of Monitoring and Research in Coastal Waters: Issues for
  Consideration from a Regulatory Point of View/,19-1

Mayer, Kathleen S., Joint Author.
  Relation of Survival to Other Endpoints in Chronic Toxicity Tests with
  Fish/,26-2

McKenney, Charles L., Jr.
  Critical Responses of Populations of Crustacea to Toxicants/,27-1

  Influence of the Organqphosphate Insecticide Fenthion on Mysidopsis bahia
  Exposed During a Complete Life Cycle: I. Survival, Reproduction, and
  Age-Specific Growth/,27-2

  Methods for Determining the Influence of Biochemical Biological Control
  Agents on Metamorphosis of Marine Crustacea/,28-1

  Optimization of Environmental Factors During the Life Cycle of Mysiodopsis
  bahia/,28-2

McKenney, Charles L., Jr., Joint Author.
  Influence of Lindane on Survival and Osmoregulatory/Metabolic Responses of
  the larvae and Adults of the Estuarine Crab, Eurypanopeus depressus/,41-2

Mclaughlin, Leslie L., Joint Author.
  Comparison of Four Methods for Calculating the EC50 from Algal Population
  Growth/,45-3
                                   PAGE  70

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                               AUTHOR INDEX
                                     M
Mclaughlin, Leslie L., Joint Author.
  Inhibition of Arm Regeneration by Ophioderma brevispina (Echinodennata,
  Ophixiroidea) by Trihutyltin Oxide and Triphenyltin Oxide/,4 6-1

  Lugworm  (Arenicola cristata) Larvae in Toxicity Tests: Survival and
  Development When Exposed to Organotins/,46-2

  Responses of Marine Unicellular Algae to Brominated Organic Corcpounds in Six
  Growth Media/,47-2

Meeter, Duane A., Joint Author.
  Quantitative Comparison of Microbial Community Structure of Estuarine
  Sediments from Microcosms and the Field/,17-3

Melius P., Joint Author.
  Polynuclear Aromatic Hydrocarbon Metabolism in Fishes/,44-3

Middaugh, Douglas P.
  Embryo Ecology of the Pacific Surf Smelt, Hypomesus pretiosus (Pisces:
  Osmeridae)/,28-3

  Influence of Environmental Temperature on Sex-ratios in the Tidewater
  Silverside, Menidia peninsulae/,29-1

  Laboratory Spawning Cues in Menidia beryllina and M. peninsulae (Pisces,
  Atherinidae) with Notes on Survival and Growth of Larvae at Different
  Salinities/,29-2

  Methods for Spawning, Culturing and Conducting Toxicity Tests with Early
  Life Stages of Atherinid Fishes/,29-3

  Reproductive Ecology of the Tidewater Silverside, Menidia peninsulae
  (Pisces: Atherinidae) from Santa Rosa Island, Florida/,30-1

Middaugh, Douglas P., Joint Author.
  Reproductive Rhythmicity of the False Grunion, Colpichthys regis, from
  Estero del Soldado, Mexico/,39-2

Miller, Robert y., Joint Author.
  Characterization of recA Mutants of Pseudomonas aeruginosa: rec-102 is a
  Mutant Allele of the Pseudomonas aeruginosa PAD recA Gene/,24-3

  Characterization of the Pseudomonas aeruginosa PAO recA Analogue and
  Identification of Its Protein Product/,25-1

  Potential for Transduction of Plasmids in Pseudomonas aeruginosa in a
  Natural Freshwater Environment/,39-3

  The Effect of Plasmid Donor Concentration and a Natural Freshwater Community
  on Transduction in Pseudomonas aeruginosa/,40-1

Montgomery, Richard M., Joint Author.
  Toxicity of Used Drilling Fluids to Mysids (Mysidopsis bahia)/,21-l

Montgomery, Stacy 0., Joint Author.
  Aerobic Metabolism of Trichloroethylene by a Bacterial Isolate/,31-2
                                   PAGE  71

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                               AUTHOR INDEX
                                     M
Montgomery/ Stacy O., Joint Author.
  Biodegradation of Trichloroethylene and the Involvement of an Aromatic
  Bicdegradative Pathway/,31-3

  Impact of Drilling Fluids on Seagrasses: An Experimental Cconunity
  Approach/,30-2

Monti, Carol A., Joint Author.
  Movement of Kepone (Chlordecone) Across an Undisturbed Sediment-Water
  Interface in Laboratory Systems/,37-3

Moody, Paul H., Joint Author.
  Acute Toxicity of Malathion, Tetrabrxawabisphenol-A, and Tributyltin Chloride
  to Mysids (Mysidopsis bahia) of Three Different Ages/,21-3

  Improved Silica Gel Cleanup Method for Organophosphorous Pesticides/,25-2

Moore, James C., Joint Author.
  Accumulation of Sediment-Bound PCBs by Fiddler Crabs/, 5-1

  Comparison of Laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shrimp,
  Mysids, and Sheepsnead Minnows/,6-1

  Field and Laboratory Toxicity Tests with Shrimp, Mysids, and Sheepsnead
  Minnows Exposed to FenthionA?-!

  Improved Silica Gel Cleanup Method for Organophosphorous Pesticides/,25-2

  Waterborne and Sediment-Source Toxicities of Six Organic Chemicals to Grass
  Shrimp (Palaemonetes pugio) and Amphioxus (Branchiostoma caribaeum)/,8-2

Morris, S.C., Joint Author.
  Application of Ion-Exchange High-Performance Liquid Chromatography in the
  Purification of 5S rFNAs Suitable for Sequence Analysis/,25-3

Morton, R. Dana
  Impact of Drilling Fluids on Seagrasses: An Experimental Coranunity
  Approach/,30-2

Mount, Donald I., Joint Author.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

  Toxic Effects on Individuals, Populations and Aquatic Ecosystems and
  Indicators of Exposure to Chemicals/, 16-3

Mueller, Len H., Joint Author.
  Bioaccumulation of Kepone by Spot (Leiostomus xanthurus): Importance of
  Dietary Accumulation and Ingestion Rate/,18-1

  Degradation of Jet and Missile Fuels by Aquatic Microbial Ccrartunities/,36-2

  Metabolism of Fenthion by Aquatic Microbial Ccramunities/,37-2

Mukherjee, Reba, Joint Author.
  Metabolism of Alachlor and Propachlor in Suspensions of Pretreated Soils and
  in Samples from Ground Water Aquifers/,32-1

                                   PAGE  72

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                               AUTHOR INDEX
                                     N
Nehlsen, Willa, Joint Author.
  Characterizing the Chesapeake Bay Ecosystem and Lessons Learned/, 18-2

Nelson, Michael J.K.
  Aerobic Biodegradation of Trichloroethylene/,31-1

  Aerobic Metabolism of Trichloroethylene by a Bacterial Isolate/,31-2

  Biodegradation of Trichloroethylene and the Involvement of an Aromatic
  Biodegradative Pathway/,31-3

Novick, Norman J.
  Metabolism of Alachlor and Propaohlor in Suspensions of Pretreated Soils and
  in Samples from Ground Water Aquifers/,32-1

                                     O
O'Brien, Mark
  Rapid Indirect Test for Chitinase Activity Using
  4-Methylumbelliferyl^-Aoetyl-B-D^lucosaiirirdde/, 32-2

O'Connor, Joseph M.
  Rharmacokinetic Model for the Accumulation of PCBs in Marine Fishes/,32-3

O'Neill, Ellen J., Joint Author.
  Aerobic Metabolism of Trichloroethylene by a Bacterial Isolate/,31-2

  Fate of Fenthion in Salt-Marsh Environments: 1. Factors Affecting Biotic and
  Abiotic Degradation Rates in Water and Sediment/, 13-1

  Metabolism of Fenthion by Aquatic Microbial Comraunities/,37-2

  Movement of Repone (Chlordecone) Across an Undisturbed Sediment-Water
  Interface in laboratory Systems/,37-3

  Physical and Biological Parameters That Determine the Fate of p-Chlorophenol
  in laboratory Test Systems/,38-1

Ogram, Andrew
  DNA Sorption to Soils and Sediments/,33-1

Ogram, Andrew, Joint Author.
  Applications for DNA Probes in Biodegradation Research/,40-2

Ogunseitan, O., Joint Author.
  Potential for Transduction of Plasmids in Pseudomonas aeruginosa in a
  Natural Freshwater Environment/,39-3

  The Effect of Plasmid Donor Concentration and a Natural Freshwater Ccraraunity
  on Transduction in Pseudomonas aeruginosa/,40-1

Ortiz-Conde, B.A., Joint Author.
  Application of Ion-Exchange High-Performance Liquid Qiromatography in the
  Purification of 5S rRNAs Suitable for Sequence Analysis/,25-3

  Distribution of Mutations in Gram Negative Eubacterial 5S rRNAs and
  Significance for Sequence Analysis/,25-4
                                   PAGE  73

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                               AUTHOR INDEX
                                     0
Qrtiz-Conde, B.A., Joint Author.
  Plasmid Mobility in the Ocean Environment/,22-2

                                     P
Parrish, Patrick R.
  Aquatic Toxicology: Ten Years in Review and a Look at the Future/,33-2

  Effects of Drilling Fluids on Marine Organisms/,34-1

  Variability of the Acute Toxicity of Drilling Fluids to Mysids (Mysidopsis
  bahia)/,34-2

Parrish, Patrick R., Joint Author.
  Drilling Fluid Test Procedure: Participation, Data Comparison and
  Implementation/,16-2

Patrick, James M., Joint Author.
  Accumulation of Sediment-Bound PCBs by Fiddler Crabs/,5-1

  Comparison of Laboratory Toxicity Test Results with Responses of Caged
  Estuarine Animals Exposed to Fenthion in the Field/,5-2

  Effects of Aerial Thermal Fog Applications of Fenthion on Caged Pink Shrimp,
  Mysids, and Sheepshead Minnows/,6-1

  Field and laboratory Toxicity Tests with Shrimp, Mysids, and Sheepshead
  Minnows Exposed to Fenthion/,7-1

  Toxicity of Sediment-Incorporated Drilling Fluids to Lancelets
  (Branchiostoma caribaeum)/,8-l

  Waterborne and Sediment-Source Toxicities of Six Organic Chemicals to Grass
  Shrimp (Palaemonetes pugio) and Amphioxus  (Branchiostoma caribaeum)/,8-2

Penttila, Daniel E., Joint Author.
  Embryo Ecology of the Pacific Surf Smelt, Hypomesus pretiosus (Pisces:
  Osmeridae)/,28-3

Pettigrew, Charles A.
  Use of DNA:DNA Colony Hybridization in the Rapid Isolation of
  4-Chlorobiphenyl Degradative Bacterial Phenotypes/,35-1

Pettigrew, Charles A., Joint Author.
  Applications for DNA Probes in Bicdegradation Research/,40-2

Pillidge, C. J., Joint Author.
  Application of Ion-Exchange High-Performance Liquid Chromatography in the
  Purification of 5S rRNAs Suitable for Sequence Analysis/,25-3

Pizza, John C., Joint Author.
  Pharmacokinetic Model for the Accumulation of PCBs in Marine Fishes/,32-3

Plaia, Gayle R., Joint Author.
  Impact of Drilling Fluids on Seagrasses: An Experimental ConMunity
  Approach/,30-2

  Responses of Estuarine Macrofauna Colonizing Sediments Contaminated with
  Fenvalerate/ ,43-1

                                   PAGE  74

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                               AUTHOR INDEX
                                     P
Plaia, Gayle R., Joint Author.
  Toxicity of Dibutyl Phthalate-Contaminated Sediment to Laboratory- and
  Field-Colonized Estuarine Benthic Communities/,44-2
Price, Kent S., Joint Author.
  Characterizing the Chesapeake Bay Ecosystem and Lessons Learned/, 18-2
Price, W. Allen
  Effects of Drilling Fluids on Thalassia testudinum and Its Epiphytic
  Algae/,35-2
Price, W. Allen, Joint Author.
  Impact of Drilling Fluids on Seagrasses: An Experimental Community
  Approach/,30-2
Pritchard, Parmely H.
  Assessing the Biodegradation of Sediment Associated Chemicals/,35-3
  Biotic and Abiotic Degradation Rates of Methyl Parathion in Freshwater and
  Estuarine Water and Sediment Samples/,36-1
  Degradation of Jet and Missile Fuels by Aquatic Microbial Communities/,36-2
  Extrapolation of Laboratory Biodegradation Information to Microcosms and
  Field Studies: A Summary of Research Results/,36-3
  Fate of Pollutants/,37-1
  Metabolism of Fenthion by Aquatic Microbial Communities/,37-2
  Movement of Kepone (Chlordecone) Across an Undisturbed Sediment-Water
  Interface in Laboratory Systems/,37-3
  Physical and Biological Parameters That Determine the Fate of p-Chlorophenol
  in Laboratory Test Systems/,38-1
Pritchard, Parmely H., Joint Author.
  Aerobic Biodegradation of Trichloroethylene/,31-1
  Aerobic Metabolism of Trichloroethylene by a Bacterial Isolate/,31-2
  Biodegradation of Trichloroethylene and the Involvement of an Aromatic
  Biodegradative Pathway/,31-3
  Biological and Abiotic Degradation Rates of Xenobiotic Chemicals in In Vitro
  Estuarine and Sediment/Water Systems/,45-2
  Fate of Fenthion in Salt-Marsh Environments: 1. Factors Affecting Biotic and
  Abiotic Degradation Rates in Water and Sediment/,13-1
  Relationship Between Reductive Dehalogenation and Other Aryl Substituent
  Removal Reactions Catalyzed by Anaerobes/,15-2
  Shake-Flask Test for Estimation of Biodegradability of Toxic Organic
  Substances in the Aquatic Environment/,14-1
  Validity of Partition Coefficient as the Adsorption Descriptor in Exposure
  Concentrations Predictions: Studies with Kepone and Methyl Parathion/,10-1
                                   PAGE  75

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                               AUTHOR INDEX
                                     R
Rao, K. Ranga
  Molt-Related Susceptibility and Regenerative Limb Growth as Sensitive
  Indicators of Aquatic Pollutant Toxicity to Crustaceans/,38-2

Ray, G.L., Joint Author.
  Field Validation of Multi-Species Laboratory Test Systems for Estuarine
  Benthic Communities/,16-1

Refermat, J., Joint Author.
  Microbial 14002 Release and Lipid Biosynthesis from Acetate, Lactate and
  Glucose in a Spartina Rhizosphere and a Nonvegetated Tidal Flat/,20-1

Riggsby, William S., Joint Author.
  Applications for DNA Probes in Bicdegradation Research/,40-2

Ritchie, Scott A.
  Evidence for Embryonic Diapause in Rivulus marmoratus: Laboratory and Field
  Observations/,39-1

Roberts, Morris H., Jr., Joint Author.
  Bioaccumulation of Kepone by Spot (Leiostomus xanthurus): Importance of
  Dietary Accumulation and Ingestion Rate/,18-1

Roszak, D.B., Joint Author.
  Plasmid Mobility in the Ocean Environment/,22-2

Russell, G.A.
  Reproductive Rhythmicity of the False Grunion, Colpichthys regis, from
  Estero del Soldado, Mexico/,39-2

                                     S
Saye, D.J.
  Potential for Transduction of Plasmids in Pseudamonas aeruginosa in a
  Natural Freshwater Environment/,39-3

  The Effect of Plasmid Donor Concentration and a Natural Freshwater Community
  on Transduction in Pseudamonas aeruginosa/,40-1

Sayler, Gary S.
  Applications for DNA Probes in Biodegradation Research/,40-2

Sayler, Gary S., Joint Author.
  DNA Sorption to Soils and Sediments/,33-1

  Gene Probes as a Tool for the Detection of Specific Genomes in the
  Environment/,2-3

  Potential for Transduction of Plasmids in Pseudamonas aeruginosa in a
  Natural Freshwater Environment/,39-3

  The Effect of Plasmid Donor Concentration and a Natural Freshwater (Community
  on Transduction in Pseudomonas aeruginosa/,40-1

  Use of DNA: DNA Colony Hybridization in the Rapid Isolation of
  4-Chlorobiphenyl Degradative Bacterial Phenotypes/,35-1
                                   PAGE  76

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                               AUTHOR INDEX
                                     S
Schcor, W. Peter
  Combined Use of Biochemical Indicators to Assess Sublethal Pollution Effects
  on Fundulus grandis, the Gulf Killifish/,41-1

Shirley, Michael A.
  Influence of Lindane on Survival and Osmoregulatory/Metabolic Responses of
  the Larvae and Adults of the Estuarine Crab, Eurypanopeus depressus/,41-2

Sinclair, James L.
  Effect of Bacterial Growth on Protozoan Predation in the Presence of
  Alternative Prey/,42-1

Sneed, Collard B., Joint Author.
  laboratory Culture and Observations on the Reproductive Biology of the
  Marine Pelagic Isopod, Idotea metallica (Crustacea; Isopoda)/,20-2

Somerville, C.C., Joint Author.
  Biodegradation of Jet Fuel by Aquatic Microbial Communities/,42-2

  Chitinase Determinants of Vibrio vulnificus: Gene Cloning and Applications
  of a Chitinase Probe/,49-2

  Plasmid Mobility in the Ocean Environment/,22-2

Spain, Carol M., Joint Author.
  Physical and Biological Parameters That Determine the Fate of p-Chlorophenol
  in Laboratory Test Systems/,38-1

Spain, Jim C.
  Biodegradation of Jet Fuel by Aquatic Microbial Communities/,42-2

Spain, Jim C., Joint Author.
  Biotic and Abiotic Degradation Rates of Methyl Parathion in Freshwater and
  Estuarine Water and Sediment Samples/,36-1

  Degradation of Jet and Missile Fuels by Aquatic Microbial Communities/,36-2

Stanley, Roman S., Joint Author.
  Responses of Estuarine Macrofauna Colonizing Sediments Contaminated with
  Fenvalerate/,43-1

  Results of Acute Toxicity Testing of Single Species Dominant in Benthic
  Community Testing at Gulf Breeze, Florida/,43-2

Straube, W., Joint Author.
  Plasmid Mobility in the Ocean Environment/,22-2

Suflita, Joseph M., Joint Author.
  Relationship Between Reductive Dehalogenation and Other Aryl Substituent
  Removal Reactions Catalyzed by Anaerobes/,15-2

Summers, Max D., Joint Author.
  Autographa californica Nuclear Polyhedrosis Virus Efficiently Enters but
  Does Not Replicate in Polikilo Thermic Vertebrate Cells/,4-1

                                     T
Tagatz, Marlin E.
  Responses of Estuarine Macrofauna Colonizing Sediments Contaminated with
  Fenvalerate/,43-1

                                   PAGE  77

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                               AUTHOR INDEX
                                     T
Tagatz, Marlin E.
  Results of Acute Toxicity Testing of Single Species Dominant in Benthic
  Community Testing at Gulf Breeze, Florida/,43-2

  Some Methods for Measuring Effects of Toxicants on Laboratory- and
  Field-Colonized Estuarine Benthic Communities/,44-1

  Toxicity of Dibutyl Fhthalate-Contaminated Sediment to Laboratory- and
  Field-Colonized Estuarine Benthic Communities/,44-2

Tan, Barrie
  Polynuclear Aromatic Hydrocarbon Metabolism in Fishes/,44-3

Teh, Swee J., Joint Author.
  Cytological Changes During Progression of Neoplasia/,23-2

Thornton, S., Joint Author.
  Field Validation of Multi-Species laboratory Test Systems for Estuarine
  Benthic Communities/,16-1

Tiedje, James M., Joint Author.
  Relationship Between Reductive Dehalogenation and Other Aryl Substituent
  Removal Reactions Catalyzed by Anaerobes/,15-2

Tippie, Virginia K., Joint Author.
  Characterizing the Chesapeake Bay Ecosystem and Lessons Learned/,18-2

Trevors, J.T.
  Gene Transfer  Among Bacteria in Soil and Aquatic Environments: A
  Review/,45-1

                                     W
Walker, William  W.
  Biological and Abiotic Degradation Rates of Xenobiotic Chemicals in In Vitro
  Estuarine and  Sediment/Water Systems/,45-2

Walker, William  W., Joint Author.
  Biotic and Abiotic Degradation Rates of Methyl Parathion in Freshwater and
  Estuarine Water and Sediment Samples/,36-1

  Shake-Flask Test for Estimation of Biodegradability of Toxic Organic
  Substances in  the Aquatic Environment/,14-1

Walsh, Gerald E.
  Comparison of  Four Methods for Calculating the EC50 from .Algal Population
  Growth/,45-3

  Inhibition of  Arm Regeneration by Ophioderma breyispina (:Echinodermata,
  Ophiuroidea) by Tributyltin Oxide and Triphenyltin Oxide/,46-1

  Lugworm (Arenicola cristata) Larvae in Toxicity Tests: Survival and
  Development When Exposed to Organotins/,46-2

  Organotin Toxicity Studies Conducted with Selected Marine Organisms at EPA's
  Environmental  Research laboratory, Gulf Breeze, Florida/,46-3

  Principles of  Toxicity Testing with Marine Unicellular Algae/,47-1
                                   PAGE  78

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                                AUTHOR INDEX
                                      W
Walsh, Gerald E.
  Responses of Marine Unicellular Algae to Broninated Organic Compounds in Six
  Growth Media/,47-2

  Techniques for Study of Effects and Uptake of Sediment-Associated
  Chemicals/,47-3

  Use of Plankton  in  Aquatic Toxicity Testing/,48-1

Walter, R., Joint  Author.
  Bacteria and the Environment/,2-2

Wang, Yei-Shung
  Biodegradation by Mineralization or Cometabolism Determined by Chemical
  Concentration and Environment/,48-2

White, David C., Joint Author.
  Quantitative Comparison of Microbial C!ommunity Structure of Estuarine
  Sediments from Microcosms  and the  Field/,17-3

Williams,  D.E., Joint Author.
  Combined Use of  Biochemical Indicators to Assess Sublethal Pollution Effects
  on Fundulus grandis, the Gulf Killifish/,41-1

Winstead, James T., Joint Author.
  Proctoeces sp. (Trematoda:  Digenea)  in Australian Oysters, Saccostrea
  commercialis and Crassostrea  amasa/,49-1

Wolf, P.H.
  Proctoeces sp. (Trematoda:  Digenea)  in Australian Oysters, Saccostrea
  commercialis and Crassostrea  amasa/,49-1

Wolfe, L.E., Joint Author.
  Field Validation of Multi-Species  Laboratory Test Systems for Estuarine
  Benthic  Communities/,16-1

Woods, M.E., Joint Author.
  Fate of  Fenthion in Salt-Marsh  Environments:  1.  Factors Affecting Biotic and
  Abiotic  Degradation Rates  in  Water and Sediment/,13-1

Wortman, A.T.
  Chitinase Determinants  of  Vibrio vulnificus:  Gene Cloning and Applications
  of a Chitinase Probe/,49-2

                                      Y
Yoder, Mark J., Joint Author.
  Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six
  Growth Media//47-2
   U.S. GOVERNMENT PRINTING OFFICE: 1987-730-013/65261
                                   PAGE  79

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