740R88101
EPA Chemical Profiles
for
Extremely Hazardous Substances
U.S. Environmental Protection Agency
June, 1988
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EPA CHEMICAL PROFILES
INTRODUCTORY INFORMATION AND FULL PROFILES
TABLE OF CONTENTS
BACKGROUND 1
DISCUSSION OF SECTIONS OF PROFILES 2
PERSONAL PROTECTIVE EQUIPMENT 5
ABBREVIATIONS 11
GLOSSARY 13
REFERENCES 23
PROFILES BY CAS NUMBER*
June 1988
* Chemical Abstracts Service Registry Number.
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EPA CHEMICAL PROFILES: INTRODUCTORY INFORMATION
BACKGROUND
The U.S. Environmental Protection Agency has developed & set of chemical
profile reference documents for use in dealing with Section 302 of Title III
of the Superfund Amendments and Reauthorization Act (SARA). These EPA
profiles contain a summary of publicly available documented information for
chemicals on the EPA list of extremely hazardous substances listed in the
Federal Register, Vol. 52, No. 77, April 22, 1987.
The profiles were originally developed in 1985 for the 402 chemicals
then called "acutely toxic chemicals" under the Chemical Emergency
Preparedness Program. When the list went into law as the list of extremely
hazardous substances, four additional chemicals were included. Forty of the
406 chemicals were subsequently deleted from the list. Profiles are provided
for the 366 chemicals listed in February, 1988, as extremely hazardous
substances. Other chemicals may be added or deleted in the future. The .
profile format was revised and the data were reviewed, augmented, and revised
as appropriate in 1987. The profiles have been reviewed for accuracy and
completeness. However, an exhaustive literature search was not performed for
each chemical, and a review of original citations has not been made. •
A profile is provided for each chemical on the list of extremely
hazardous substances. Profiles are presented in ascending order of Chemical
Abstract Service (CAS) registry numbers. One chemical (generic name:
organorhodium complex) is identified by a premanufacture review notice (PMN)
number and appears first.
The CAS number was used to search the automated Toxicology Data Base
(TDB) or Hazardous Substance Data Bank (HSDB) from the National Library of
Medicine (NLM). If available, TDB/HSDB files were retrieved. Approximately
65 percent of the chemicals were listed in the TDB/HSDB files. For these
chemicals, the TDB/HSDB files provided the main source of information for the
profiles. All data obtained from the TDB/HSDB were indicated by an asterisk
(*) followed by a reference to the TDB/HSDB citation, (e.g., (*Merck 1976)).
For those chemicals without a TDB/HSDB file, a limited number of standard
reference materials was searched. Such references are cited by author, year,
and page number. A master list of references, including the secondary
references cited in TDB/HSDB, has been prepared and may be found in the
Reference Section of this document. The abbreviations used in the profiles
have been defined in a master list and may be found in the Abbreviation
Section. Medical terms not commonly used have been included in a Glossary
Section. Dorland's Medical Dictionary (1974) was used to provide most of the
definitions in the Glossary.
If information was not available for a specific compound but the
chemical could be categorized, then general information about the chemical
category was included. Such information is indicated, for example, by the
notation "Non-Specific -- Organophosphorus Pesticide" or "Non-Specific --
Poisonous Solid, n.o.s.".
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DISCUSSION OF SECTIONS OF PROFILES
Each profile includes chemical identity information and eight sections
containing information on regulations, properties, hazards, uses, and
precautions. Comments on the elements of the profiles are presented below.
Chemical Identity. The name given on the profile is the name used on
the list of extremely hazardous substances (Section 302 of SARA Title III)
and is one of the most common names.
CAS Registry Number. The number is identical to the number listed in
the National Institute of Occupational Safety and Health (NIOSH) Registry of
Toxic Effects of Chemical Substances (RTECS).
Synonyms. Synonyms from TDB/HSDB files are listed without citation.
Synonyms from NIOSH/RTECS (1983) or the Structure and Nomenclature Search
System (SANSS) (1983) , or other sources are referenced. The 9th Collective
Index (CI) name from the SANSS 1983 database was added to each profile when
the 9th CI name was different from the 8th CI name.
Chemical Formula and Molecular Weight. Data from TDB/HSDB or
NIOSH/RTECS (1983) are not cited. Formulas or molecular weights found in
other sources are cited.
Section I -- Regulatory Information. The toxicity value that placed the
chemicals on the list has been included in this section. These toxicity data
were obtained from a screen of the NIOSH/RTECS on-line computer file and are
also cited with an asterisk (*) (e.g., *NIOSH/RTECS 1985). Toxicity data
were not included for chemicals listed on the basis of high production volume
and known toxicity ("Other" chemicals).
Also included are Threshold Planning Quantities (TPQs) and Reportable
Quantities (RQs), as listed in the Final Rule (Federal Register, Volume 52,
Number 77, April 22, 1987).
An indication of whether the chemical is listed under Section 313 of
Title III of SARA is included; if the chemical falls into a chemical category
listed in Section 313, the category is given.
Section II -- Physical/Chemical Characteristics. Physical state (solid,
liquid, or gas) at ambient conditions is listed, as given in the Interim
Final Rule (Federal Register, Vol. 51, No. 221, November 17, 1986); no
reference is cited on the profiles. Other properties are included with
references.
Section III -- Health Hazard Data. Generally, only human data are
reported in the Health Hazard Data section. The following exposure limits
are included, if available:
• Occupational Safety and Health Administration (OSHA)
Permissible Exposure Limits (PELs);
• American Council of Governmental Industrial Hygienists (ACGIH)
Threshold Limit J/alues (TLVs); and
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• Immediately Dangerous to Life and Health (IDLH) levels
developed by N10SH.
The following limits may be listed under Other Limits Recommended, if
available:
• NIOSH recommendations;
• EEGLs (emergency exposure guidance levels);
• SPEGLs (short-term public emergency guidance levels);
• Human carcinogens or suspect carcinogens listed by the ACGIH;
• OSHA carcinogens; and
• NIOSH potential occupational carcinogens.
EEGLs and SPEGLs, developed by the National Research Council of the National
Academy of Sciences, are discussed in more detail in Appendix D of the
Technical Guidance for Hazards Analysis (EPA 1987). An EEGL is defined as an
acceptable concentration for unpredicted, single, short-term emergency
exposure of a defined occupational group (EEGLs have been developed for
military personnel). A SPEGL is defined as an acceptable concentration for
unpredicted, single, short-term, exposure of the general public in
emergencies.
Information on the route of exposure and health hazards often was not
available or only partially available for specific chemicals. Health hazard
data often were not found specific to dose, route of entry or exposure type
(acute, delayed, or chronic). Generic information on the chemical category
was provided, wherever possible, in the absence of information on the
specific chemical.
Section IV -- Fire and Explosion Hazard Data. In the absence of
chemical-specific information, generic information is provided whenever the
chemical could be categorized. National Fire Protection Association (NFPA)
flammability ratings from the NFPA Fire Protection Guide on Hazardous
Materials are included if available.
Section V -- Reactivity Data. In the absence of chemical-specific
information, generic information is provided whenever the chemical could be
categorized.
Section VI -- Use Information. This section includes uses of the
chemical as reported in HSDB or other sources.
Section VII -- Precautions for Safe Handling and Use. Chemical-
specific information often was not available; therefore, generic information
for the chemical category often is presented.
Section VIII -- Protective Equipment for Emergency Situations. This
section contains recommendations for the type of personal protective
equipment to be used. See page 5 for a detailed discussion of personal
protective equipment.
Section IX -- Emergency Treatment Information. This section contains
information on signs and symptoms of poisoning and emergency treatment
information for first responders. Emergency planners may be especially
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interested in references to medical equipment and supplies that could be
useful in case of the accidental release of the extremely hazardous
substance.
Approximately 120 of the revised chemical profiles contain complete
revisions of the emergency treatment information section and have been
retitled the Emergency First Aid Treatment Guide (EFATG). This new section
has been reformatted and contains more detailed guidance for emergency
treatment based on information obtained from the Rocky Mountain Poison
Center's proprietary data base, Poisindex. The order of completion of
EFATG's is being carried out by priority based on considerations of toxicity,
production volume, and availability of specific emergency treatment
information. Revisions of the emergency treatment information sections for
the remaining profiles is underway and will be published as soon as they are
completed. In the meantime, these profiles contain the emergency treatment
information that was originally published in 1986.
Because the emergency treatment information is designed for use by first
responders, references to signs and symptoms of exposure as well as
procedural guidance avoid the use of highly technical medical language.
Signs and symptoms are not distinguished by route of exposure. Emergency
treatment procedures, on the other hand, are presented according to route of
exposure, with emphasis on the inhalation and dermal routes. References to
invasive treatments are limited, since the emergency treatment information is
directed to first responders rather than medical practitioners. First
responders must be aware of particular state and local regulations which
govern the extent of invasive treatment that they may perform.
The Agency for Toxic substances and Disease Registry (ATSDR) has
provided general review of the EFATf-'s for format and content.
Comments. This section is provided, in some cases, to list the sources
that were checked for information in cases of chemicals for which few data
were available. In general, this section pertains to chemicals without
TDB/HSDB files.
Not Found. This statement on the profile can mean that:
• The value or information was not found in the references used;
• The value or information probably does not exist for this
chemical; or
• The value is meaningless or not applicable for this chemical.
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PERSONAL PROTECTIVE EQUIPMENT
Personal protective equipment (PPE) for emergency response situations
involving extremely hazardous substances must be selected carefully and used
properly. The PPE should protect the respiratory system, skin, eyes, face,
hands, feet and body from chemical, physical and biological hazards that may
be encountered during an emergency response action. Selection of the proper
personal protective equipment must consider the specific hazards responders
are likely to encounter at a particular site. Selection is a complex task
and should be performed only by individuals with proper training and
experience.
Regulatory Requirements and Other Standards. Selection, use, training
and programs for PPE for emergency response situations may be covered by
regulations and standards under the Occupational Safety and Health
Administration (OSHA) 29 CFR 1910, Environmental Protection Agency (EPA)
regulations and recommendations, Department of Transportation (DOT)
regulations, or National Fire Protection Association (NFPA) standards.
Personal Protective Equipment for Emergencies. During an emergency
involving extremely hazardous substances, a wide variety of conditions may
occur. Therefore, response personnel should wear maximum protection
initially until actual conditions at the site are evaluated. Maximum
protection is designed to provide the highest available level of respiratory,
skin and eye protection. Recommended equipment consists of a positive
pressure, pressure-demand full facepiece self-contained breathing apparatus
(SCBA) or full facepiece supplied air respirator with escape SCBA and a
fully-encapsulating chemical-resistant suit. In addition, other equipment
such as inner chemical-resistant gloves, chemical-resistant safety
boots/shoes, and two-way radio communications, a cooling unit, coveralls,
long cotton underwear, hard hat, disposable gloves and boot covers may be
worn as needed.
Figure 1 gives an example of a worker outfitted in a fully-
encapsulating suit with respiratory protection. Note that if the fully-
encapsulating suit does not have integral gloves and boots, then glove/suit
and boot/suit joints should be sealed with tape.
Respiratory Protection. Positive pressure self-contained breathing
apparatus (SCBA) should be worn by employees engaged in emergency response
and exposed to hazardous substances until it is determined that a decreased
level of respiratory protection will not result in hazardous exposures to
employees (See OSHA 29 CFR 1910.120 Hazardous Waste Operations and Emergency
Response).
Chemical Protective Clothing and Equipment. The selection of chemical
protective clothing is a complex process and many factors must be considered
such as: the nature of the hazard; the potential route of exposure; the
tasks to be accomplished; and the performance of the protective equipment
materials in forming a barrier to the chemical substances encountered at a
site. No protective equipment material protects against all chemicals and
combinations of chemicals. In many cases, the chemical substance may
permeate or break through the protective equipment;material, exposing the
wearer to the chemical. It is important to note that the information
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Figure 1. FULLY ENCAPSULATING CHEMICAL-RESISTANT SUI
Respiratory Protection Must be Worn with this Type of S
From "Guidelines for the Selection of Chemical Protective C!
3rd Edition.
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presented for an individual chemical may not be applicable when that chemical
is present in a mixture, as the ability of a chemical in a mixture to
permeate a material may differ from that of the pure chemical. Further
studies are needed to evaluate the characteristics of mixtures of chemicals
in relation to materials for personal protective equipment.
The chemical profiles give general information on the chemical
resistance of various suit materials to provide a basis for a decision on
whether suit materials are adequate. This information is available for about
half of the chemicals on the list of extremely hazardous substances. The
chemical resistance information for each suit material is indicated on the
profiles by the entries shown below. Explanations of their meanings follow
the entries.
• Excellent Resistance/Many Data means there is quantitative
information indicating that the material demonstrates
excellent chemical resistance to the substance.
• Good Resistance/Limited Data means there is quantitative
information indicating that the material demonstrates good
chemical resistance to the substance.
• Poor Resistance/Many Data means there is quantitative
information indicating that the material demonstrates poor
chemical resistance to the substance.
• Poor Resistance/Limited Data means there is quantitative
information indicating that the material demonstrates poor
chemical resistance to the substance.
• Good Resistance/Limited Data* means there is qualitative
information indicating that the material demonstrates good
chemical resistance to the substance. Most of this
information is based on qualitative ratings from glove
material manufacturers and may or may not be based on actual
testing. This entry on the profile is intended to provide
general guidance in selecting chemical protective clothing.
• Poor Resistance/Limited Data* means there is qualitative
information indicating that the material demonstrates poor
chemical resistance to the substance. Most of this
information is based on qualitative ratings from glove
material manufacturers and may or may not be based on actual
testing. This entry on the profile is intended to provide
general guidance in selecting chemical protective clothing.
• Good Resistance/Limited Data** means there is qualitative or
quantitative information indicating that the material
demonstrates good chemical resistance based on the generic
family of chemicals to which the substance belongs. Most of
this information is not based on testing done on the substance
itself. This entry on the profile is intended to provide
general guidance to the initial selection of chemical
protective clothing and to narrow the scope of alternative
materials.
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• Poor Resistance/Limited Data** means there is qualitative or
quantitative information indicating that the material
demonstrates poor chemical resistance based on the generic
family of chemicals to which the substance belongs. Most of
this information is not based on testing done on the substance
itself. This entry on the profile is intended to provide
general guidance to the initial selection of chemical
protective clothing and to narrow the scope of alternative
materials.
Remember that this information provides guidance only and is not a
guarantee that the suit will protect an individual from prolonged or repeated
exposure and may not provide adequate protection for mixtures of chemicals.
Consult reference 1 for more information. Also, be sure to consult with
facility representatives for additional information. Other considerations
include durability and flexibility of the chemical protective clothing, and
heat stress. Table 1 lists the fully-encapsulating suit materials available
on the market as of February, 1987. (See non-mandatory Appendix B of OSHA 29
CFR 1910.120 for more information).
Special Use Considerations. Fire, heat, explosion and radiation require
special-protective equipment. It is important to provide protection from
these hazards in addition to chemical hazards. Section IV of the profiles
entitled Fire and Explosion Hazard Data should be consulted for further
information. (See OSHA 29 CFR 1910.156, DOT and NFPA standards and
recommendations for more information.)
Decontamination. Decontamination of personal protective equipment
should be tailored to the specific conditions at the site and will vary
accordingly. (See non-mandatory Appendix D of OSHA 29 CFR 1910.120 for
additional information).
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TABLE 1. AVAILABLE FULLY-ENCAPSULATING SUIT MATERIALS
AS OF FEBRUARY, 1987*
1. Butyl Rubber/Nylon (BUTYL)
2. Butyl Rubber, Sheet (BUTYL)
3. Butyl/Fabric/Butyl (BUTYL)
4. Butyl/Nylon/Butyl (BUTYL)
5. Butyl/Polyester/Chloroprene Rubber (BUTYL/NEOPRENE)
6. Chlorinated Polyethylene (CPE)
7. Chlorobutyl Rubber/Nomex (CHLOROBUTYL)
8. Chlorobutyl/Nomex/Chlorobutyl (CHLOROBUTYL)
9. Chloroprene Rubber/Nylon (NEOPRENE)
10. Chloroprene Rubber, Sheet (NEOPRENE)
11. Fluoroelastomer/Butyl/Nylon/Butyl (VITON/BUTYL)
12. Fluoroelastomer/Fabric/Fluoroelastomer (VITON)
13. Fluoroelastomer/Nylon/Chloroprene (VITON/NEOPRENE)
14. Fluoroelastomer/Polyester/Chlorobutyl (VITON/CHLOROBUTYL)
15. Fluoroelastomer, Sheet (VITON)
16. Nitrile/Fabric (NITRILE)
17. PE/Polyvinylidenechloride/PE/Tyvek (SARANEX)
18. Polyethylene/Tyvek (PE)
19. Polyvinyl Chloride/Fabric (PVC)
20. Polyvinyl Chloride/Fabric/Polyvinyl Chloride (PVC)
21. Polyvinyl Chloride/Nylon (PVC)
22. Polyvinyl Chloride/Nylon/Polyvinyl Chloride (PVC)
23. Polyvinyl Chloride, Sheet (PVC)
24. Sontara (NONWOVEN FABRIC)
25. TFE/Fiberglass/TFE (TEFLON)
26. TFE/Nomex/TFE (TEFLON)
27. Tyvek (NONWOVEN PE)
Schwope, A.D., et al. Guidelines for the Selection of Chemical
Protective Clothing, 3rd Edition. Cincinnati: American Conference of
Governmental Industrial Hygienists, Inc., 1987.
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PERSONAL PROTECTIVE EQUIPMENT REFERENCES
1.1 Schwope, A.D. ; P.P. Costas; J.O. Jackson; J.O. Stull; and D.J. Weitzman.
Guidelines for the Selection of Chemical Protective Clothing. 3rd
Edition. Cincinnati: American Conference of Governmental Industrial
Hygienists, Inc., 1987.
2. Certified Equipment List as of October 1, 1986. DHHS (NIOSH) No. 87-
102. Cincinnati: National Institute for Occupational Safety and
Health, 1986.
3. Criteria for a Recommended Standard ... Occupational Exposure to Hot
Environments Revised Criteria 1986. DHHS (NIOSH) No. 86-113.
Cincinnati: National Institute for Occupational Safety and Health,
1986.
4. National Institute for Occupational Safety and Health; Occupational
Safety and Health Administration; U.S. Coast Guard; U.S. Environmental
Protection Agency. Occupational Safety and Health Guidance Manual for
Hazardous Waste Site Activities. DHHS Occupational Safety and Health,
1985.
5. Occupational Safety and Health Administration 29 CFR 1910 Occupational
Safety and Health Standards, especially 29 CFR 1910.120 Hazardous Waste
Operations and Emergency Response.
6. National Fire Protection Association standards and recommendations, such
as NFPA 704M, 1500 and 1981.
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ABBREVIATIONS
ACGIH
ADI
AIHA
BAL
GAS
CC
CNS
EEC
EEGL
EKG
EPA
IARC
ID1H
1m
LCLO
LC50
LDLO
LD50
T,ET,
m3
mg/Kg
nnnHg
NIOSH
n.o.s.
American Conference of Government and Industrial Hygienists
Acceptable Daily Intake
American Industrial Health Association
Dimercaprol (British anti-lewisite)
Chemical Abstracts Service
Closed cup
Central Nervous System
Electroencephalogram
Emergency Exposure Guidance Level developed by the National
Research Council (NRC)
Electrocardiogram
Environmental Protection Agency
International Agency for Research on Cancer
Immediately Dangerous to Life and Health
intramuscularly
Lethal Concentration Low; the lowest concentration at which
death occurred
Lethal Concentration 50; the concentration at which 50% of the
animals died; a calculated value
Lethal Dose Low; the lowest dose at which death occurred
Lethal Dose 50; the dose at which 50% of the animals died; a
calculated value
Lower Explosive Limit
Cubic meter
milligrams per kilogram
millimeters of mercury; a measure of pressure
National Institute of Occupational Safety and Health
Not otherwise specified
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NRG
NTP
OC
OSHA
PEL
ppb
ppm
RBC
RTECS
SANSS
SPEGL
STEL
TCC
TOG
TDLO
TLV
TWA
DEL
ug
2-PAM
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ABBREVIATIONS (Confd)
National Research Council, National Academy of Sciences
National Toxicology Program
open cup
Occupational Safety and Health Administration
Permissible Exposure Level
parts per billion
parts per million
Red blood cell(s)
Registry of Toxic Effects of Chemical Substances
Structure and Nomenclature Search System
Short-term Public Exposure Guidance Level developed by the NRC
Short-term exposure limit
Tagliabue Closed Cup, a standard method of determining flash
point
Tagliabue Open Cup, a standard method of determining flash
point
Toxic Dose Low; the lowest dose at which toxicity occurred
Threshold Limit Value
Time Weighted Average
Upper Explosive Limit
microgram
pralidoxime
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GLOSSARY
Acaricide
Acidosis
Acneform
Albuminuria
Alopecia
Amorphous
Anaphylactoid
Anorexia
Anoxia
Anthelmintic
Anticoagulant:
Antilewisite
Antimetabolite
Antipyretic
Aphasia
Aplasia
Ar gyrosis
an agent that destroys mites
pathologic condition resulting from
accumulation of acid in, or loss of base
from, the blood or body tissues
resembling acne
presence of serum albumin in the urine
baldness; absence of hair from skin areas
where it is usually present
without definite form, not crystallized
resembling an unusual or exaggerated
allergic reaction to foreign protein or
other substances
lack or loss of appetite for food
absence of lack of oxygen; reduction of
oxygen in the body tissues below
physiologic levels
an agent that is destructive to worms
especially of the intestine
an agent that prevents blood clotting
dimercaprol; also called British anti-
lewisite, or BAL
a substance that interferes with
utilization of an essential metabolite
an agent that relieves or reduces fever
defect or loss of power of expression by
or comprehension of speech, writing, or
signs
lack of development of an organ or tissue,
or the cellular products from an organ or
tissue; germinal aplasia -- complete
failure of gonad development
poisoning by silver or a silver salt,
evidenced by ashen-gray discoloration of
skin
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GLOSSARY (Cont'd)
Arrhythmia
Arteriosclerosis
Asthenia
Astringent
Ataxis
Avicide
Bioaccumulation
Bradycardia
Bronchoconstriction
Calcification
Carcinogenic
Cardiac
Cathartic
Cheyne -Stokes respiration
Chloracne
Clonic
Conj unct ivitis
Contraindication
any variation from the normal rhythm of
the heart beat
hardening and thickening of the walls of
the smaller arteries
lack or loss of strength; weakness
causing contraction, usually locally after
surface application
failure of muscular coordination;
irregularity of muscular action
an agent that kills birds
increased concentrations of a chemical in
an organism compared to the surrounding•
environment
slowness of the heart beat, as evidenced
by slowing of pulse rate to less than 60
narrowing of the air passages of the lungs
process by which organic tissue becomes
hardened by a deposit of calcium salts
within its substance
producing or inciting cancer
pertaining to the heart
causing evacuation of the bowels; laxative
respiratory distress related to posture
(especially reclining at night) that
occurs in association with heart disease
acne-like eruption caused by exposure to
chlorine compounds
pertaining to alternate muscular
contraction and relaxation in rapid
succession
inflammation of the lining of the eyelids
any condition which renders some
particular line of treatment improper or
undesirable
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GLOSSARY (Cont'd)
Cryogenic
Cyanosis
Decoction
Demulcent
Dermal
Dermatitis
Desiccant
Diluent
Diuresis
Diuretic
DS2
Ductile
Dyspnea
Ectoparasiticide
Edema
Ernesis
Enteritis
Epigastric
Epileptiform
Epithelium
pertaining to or causing the production of
low temperatures
bluish discoloration, especially of the
skin and mucous membranes and fingernail
beds
substance prepared by boiling
soothing
pertaining to the skin
inflammation of the skin
a drying agent
a diluting agent
increased secretion of urine
agent that increases urine production
standard decontaminant for chemical
warfare agents; contains 70% diethylene
triamine, 28% ethylene glycol monomethyl
ether, and 2% sodium hydroxide
capable of being drawn out or hammered
thin
difficult or labored breathing
an agent that kills parasites living on
the exterior of its host
presence of abnormally large amounts of
fluid in intercellular spaces of body
tissues
vomiting
inflammation of the intestine
pertaining to the upper-middle region of
the abdomen
occurring in severe or sudden spasms
cells covering the internal and external
surfaces of the body
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GLOSSARY (Cont'd)
Erythema
Exothermic
Explosive
Flammable
Gastrointestinal
Germinalaplasia
Glomerular
Half-life
Halon
Health Hazard
Acute
Chronic
Delayed
Hematoma
Hematuria
Hemoglohinuria
Hemolysis
Hemolytic
Hepatic
redness of the skin produced by congestion
of the capillaries
characterized by or formed with evolution
of heat
characterized by or relating to bursting
forth with sudden violence or noise from
internal energy; relating to a rapid
reaction with production of noise, heat,
and violent expansion of gases
capable of being easily ignited and
supporting combustion
pertaining to the stomach and intestine
lack of development of egg and sperm cells
pertaining to a tuft or cluster, as of
blood vessels or nerve fibers
the time in which the concentration of a
substance will be reduced by half
halogenated hydrocarbon (e.g., carbon
tetrachloride)
immediate toxic effects
persistent or prolonged injury
toxic effect occurring after a lapse of
time
localized collection of blood, usually
clotted, in an organ, space, or tissue,
due to a break in the wall of the blood
vessel
blood in the urine
presence of free hemoglobin in the urine
separation of hemoglobin from red blood
cells and its appearance in the plasma
pertaining to or characterized by
hemolysis
pertaining to the liver
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GLOSSARY (Cont'd)
Humectant
Hydrolysis
Hygroscopic
Hyperactivity
Hyperalimentation
Hyperbilirubinemia
Hypercalcemia
Hyperparathyroidism
Hyperpyrexia
Hyperreflexia
Hypersalivation
Hypertens ion
Hypervitaminosis
Hypobilirubinemia
Hypocalcemia
Hypovolemic
Hypoxemia
Hypoxia
Interstitial Pneumonia
moistening or diluent substance
decomposition reaction involving the
splitting of a chemical substance by water
readily taking up and retaining moisture
(water)
abnormally increased activity
ingestion or administration of a greater
than optimal amount of nutrients
an excess of bilirubin in the blood
excess of calcium in the blood
abnormally increased activity of the
parathyroid glands which affects and is
affected by serum calcium levels
a highly elevated body temperature
exaggeration of reflexes
excessive secretion of saliva
persistently high arterial blood pressure
condition due to ingestion of an excess of
one or more vitamins
abnormally low levels of bilirubin in the
blood
abnormal reduction of blood calcium levels
pertaining to an abnormally decreased
volume of circulating fluid (plasma) in
the body
deficient oxygenation of the blood
low oxygen content or tension; deficiency
of oxygen in the inspired air
a chronic form of pneumonia with increase
of the interstitial tissue and decrease of
the proper lung tissue
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GLOSSARY (Cont'd)
Isotonia
Jaundice
Lachrymator (or lacrimator)
Lacrimation
Laryngospasm
Larynx
Lassitude
Latency
Lesion
Lethal
Leukopenia
Lewisite
Malaise
Mania
Metastatic
Methemoglobinemia
Miosis (or myosis)
a solution having the same effective
osmotic pressure as the body fluid to
which it is compared
syndrome characterized by
hyperbilirubinemia and deposition of bile
pigment in the skin, resulting in yellow
appearance of the patient
a substance which increases the flow of
tears
secretion and discharge of tears
spasmodic, closure of the larynx
the muscular and cartilage structure
situated at the top of the trachea
(windpipe) and below the root of the
tongue, functioning as sphincter into the
trachea and as the organ of voice
weakness; exhaustion
a state of seeming inactivity
a pathological or traumatic discontinuity
of tissue or loss of function of a part
deadly; fatal
reduction in the number of leukocytes in
the blood
a lethal war gas which is a vesicant,
lacrimator and lung irritant
a vague feeling of bodily discomfort
a phase of mental disorder characterized
by an expansive emotional state, elation,
overtalkativeness, and increased motor
activity
pertaining to the transfer of disease from
one organ or part to another not directly
connected with it
presence of methemoglobin (oxidized
hemoglobin) in the blood
contraction of the pupil
-------
-19-
GLDSSARY (Cont'd)
Miscible
Mordant
Mutagenic
Mydriasis
Myelosuppression
Narcotic
Necrosis
Nephritis
Neural
Neuropathy
Neurotoxicity
Nocturia
Ocular
Oliguria
Ophthalmic
Osteosclerosis
Palpitation
Parasympathomimetic
capable of mixing in any ratio without
. separation of two phases
a chemical that fixes a dye in or on a
substance by combining with the dye to
form an insoluble compound
inducing genetic mutation
extreme dilation of the pupil
suppression of the formation of bone
marrow
an agent that produces insensibility or
stupor
death of tissue, usually as individual
cells, group of cells, or in localized
areas
inflammation of the kidney
pertaining to a nerve or to the nerves
functional disturbances and/or
pathological changes in the peripheral
nervous system
exerting a destructive or poisonous effect
en nerve tissue
excessive urination at night
pertaining to or affecting the eye
secretion of a diminished amount of urine
in relation to fluid intake
pertaining to the eye
hardening or abnormal density of bone
unduly rapid heart beat which is noted by
the patient; it may be regular or
irregular
producing effects resembling time of
stimulation of the parasympathetic nerve
supply to a part; called also cholinergic
-------
-20-
GLOSSARY (Cont'd)
Parenteral
Paresthesia
Perfusion
Pharynx
Photophobia
Photosens itize
Phytotoxic
Polydipsia
Precordial
Proteinuria
Psychosis
Psychotropic
Pulmonary
Rales
Recumbent
Renal
Scotoma
not through the alimentary canal but
rather by injection through some other
route, such as subcutaneous,
intramuscular, intravenous, etc.
an abnormal sensation, as burning or
prickling
liquid poured over or through an organ or
tissue
the muscular membrane sac between the
mouth and nostrils and the esophagus
abnormal visual intolerance of light
to induce a state of abnormal
responsiveness to the influence of light
poisonous to plants; inhibiting plant
growth
excessive thirst persisting for long
periods of time
pertaining to the region over the heart
and lower part of the thorax
an excess of serum proteins in the urine;
also called albuminuria
any major mental disorder characterized by
derangement of the personality and loss of
contact with reality
exerting an effect upon the mind; capable
of modifying mental activity
pertaining to the lungs
abnormal respiratory sound heard when
listening for sounds within the body
lying down
pertaining to the kidney
an area of depressed vision within the
visual field, surrounded by an area of
less depressed or normal vision
-------
-21-
GLOSSARY (Cont'd)
Supertropical Bleach
Systemic
Tachycardia
Tepid
Teratogenic
Tetanic
Thrombocytopenia
Tidal volume
Tinnitus
Toxic
Triglyceridemia
Urticaria
Vasodilation
Ventrictilar fibrillation
Vertigo
bleaching agent containing calcium
hypochlorite (a powerful oxidizer) and
calcium oxide (a corrosive material)
pertaining to or affecting the body or
organism as a whole
excessively rapid heart beat
moderately warm; lukewarm
tending to produce anomalies of formation
or development
pertaining to or of the nature of tetanus,
a disease characterized by muscle spasm
decrease in the number of blood platelets
amount of gas that is inhaled and exhaled
during one respiratory cycle
a noise in the ears, such as ringing,
buzzing, roaring, clicking
pertaining to, due to, or of the nature of
a poison
excess of triglycerides in the blood
a vascular reaction of the skin marked by
the transient appearance of smooth,
slightly elevated patches (wheals) which
are redder or paler than the surrounding
skin and often attended by severe itching
dilation (expansion of a vessel,
especially of arterioles leading to
increased blood flow to a part
irregular heart beat characterized by
uncoordinated contractions of the
ventricle
dizziness; an illusion of movement as if
the external world were revolving around
an individual or as if the individual were
revolving in space
Vesicant
causing blisters
-------
-22-
GLOSSARY (Conf d)
Volatile -- readily vaporizable at a relatively low
temperature
-------
-23-
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-------
-24-
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-25-
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-26-
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* NIOSH. 1976. National Institute for Occupational Safety and Health,
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* NIOSH. 1975. National Institute for Occupational Safety and Health,
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Center for Disease Control. Registry of toxic effects of chemical
substances. 1975 ed. Washington, D.C.: U.S. Government Printing
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* NIOSH, 1974. National Institute for Occupational Safety and Health,
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* NIOSH. 1973. National Institute for Occupational Safety and Health,
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Stricoff RS, Partridge LJ, Jr., eds. NIOSH/OSHA pocket guide to
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/- NIOSH/OSHA. 1978. National Institute for Occupational Safety and
Health/Occupational Safety and Health Administration, U.S. Department of
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-------
-35-
REFERENCES (Cont'd)
/- NIOSH/RTECS. 1987. National Institute for Occupational Safety and
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* NIOSH/RTECS. 1985. National Institute for Occupational Safety and
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/- NRC. 1984b. National Research Council. Emergency and continuous
exposure limits for selected airborne contaminants, Vol. 2. Washington,
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/- NRC. 1984c. National Research Council. Emergency and continuous
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/- NRC. 1985a. National Research Council. Emergency and continuous
exposure limits for selected airborne contaminants, Vol. 4. Washington,
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exposure limits for selected airborne contaminants, Vol. 5. Washington,
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exposure limits for selected airborne contaminants, Vol. 6. Washington,
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/- NRC. 1987. National Research Council. Emergency and continuous
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* NRC. 1983. National Research Council. Drinking water and health, Vol.
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* NRC. 1982. National Research Council. Drinking water and health, Vol.
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-------
-36-
REFERENCES (Cont'd)
* NRC. 1983. National Research Council. Polycyclic aromatic
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* NRC. 1981. National Research Council. Prudent practices for handling
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* NRC. 1980a. National Research Council. Drinking water and health,
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* NRC. 1980b. National Research Council. Drinking water and health,
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* Opavsky W, MacPherson E. 1976. Ger Offen Patent Number 2430193,
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*/- OSHA. 1984. Occupational Safety and Health Administration, U.S.
Department of Labor. Occupational safety and health standards. Subpart
Z. Toxic and hazardous substances. (29 CFR 1910..1000). pp. 660-665.
* Osol A, ed. 1980. Remington's pharmaceutical sciences. 16th ed.
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Philadelphia: J.B. Lippincott.
* Parke DV. 1968. The biochemistry of foreign compounds. Oxford:
Pergamon Press.
* Parr JF, Marsh PB, Kla JM, eds. 1983. Land treatment of hazardous
wastes. Park Ridge, NJ: Noyes Data Corporation.
* Patty F, ed. 1963. Industrial hygiene and toxicology: Vol II:
toxicology. 2nd ed. New York: Interscience Publishers.
-------
-37-
REFERENCES (Cont'd)
Peer Review Committee. Updated 1985. Expert opinion on Data Base.
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Perry R.H., ed. 1984. Perry's Chemical Engineer's Handbook. 6th ed.
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Physicians' Desk Reference. 1980, 1985. 34th ed. and 39th ed.
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Economics Co.
Proctor NH, Hughes JP. 1978. Chemical hazards of the workplace.
Philadelphia: J.B. Lippincott Co.
Roberts NJ. 1983. South Med. J. 76(1)45-48.
Rodricks JV, Hesseltine CW, Mehlman MA, eds. 1977. Mycotoxins in human
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Rossoff IS. 1974. Handbook of veterinary drugs. New York: Springer
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Rumack BH, ed. 1975-Present. Poisindex. Microfiche ed. Denver, CO:
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SANSS. 1983. Structure and Nomenclature Search System. Chemical
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update November 1983.
Sax NI, ed. 1986. Rapid guide to hazardous chemicals in the workplace.
New York: Van Nostrand Reinhold Co.
Sax NI. 1984. Dangerous properties of industrial materials. 6th ed.
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Sax NI. 1979. Dangerous properties of industrial materials. 5th ed.
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Sax NI. 1975. Dangerous properties of industrial materials. 4th ed.
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Sax NI. 1968. Dangerous properties of industrial materials. 3rd ed.
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Schuckmann, F. 1972. Zentralarbeitsmed Arbeitsschutz 22(3):74.
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American Chemical Society. ACS Monograph 173.
-------
-38-
REFERENCES (Cont'd)
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Soliman et al. 1979. J. Environ Sci Health, Part B B14(l)27.
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Spencer EY. 1973. Guide to the chemicals used in crop protection, 6th
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SRI. 1983. Standard Research Institute International. 1983 Directory
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Sunshine I, ed. 1969. CRC handbook of analytical toxicology.
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-------
-39-
REFERENCES (Cont'd)
/- U.S. Army. 1975. Headquarters, Department of the Army. Military
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* Usdin E, Efron DH. 1972. Psychotropic drugs and related compounds.
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* USEPA. 1980. U.S. Environmental Protection Agency. Ambient Water
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033).
* USEPA/ECAO. 1980. U.S. Environmental Protection Agency/Environmental
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* USEPA/ODW. 1983. U.S. Environmental Protection Agency. Office of
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/- USEPA/Pesticide Index. 1985. U.S. Environmental Protection Agency.
EPA Index to Pesticide Chemicals: Use and Limitations. Current file;
updated daily. Washington, D.C.: Office of Pesticide Programs, USEPA.
/- USEPA/Active Ingredients. 1985. U.S. Environmental Protection Agency.
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* USFWS. 1984. U.S. Fish and Wildlife Service, Department of the
Interior. Handbook of toxicity of pesticides to wildlife. Washington,
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* USFWS. 1980. U.S. Fish and Wildlife Service, Department of the
Interior. Handbook of acute.toxicity of chemicals to fish and aquatic
invertebrates. Washington, D.C.: U.S. Government Printing Office.
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* USFWS. 1975. U.S. Fish and Wildlife Service, Department of the
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* USFWS. 1972. U.S. Fish and Wildlife Service, Department of the
Interior, Bureau of Sports Fisheries and Wildlife. Comparative dietary
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Printing Office. Special Scientific Report -- Wildlife No. 152.
-------
-40-
REFERENCES (Confd)
*-. USFWS. 1970. U.S. Fish and Wildlife Service, Department of the
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Champaign, IL: Weed Science Society of America.
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New York: Marcel Dekker.
-------
-41-
REFERENCES (Conf d)
* White-Stevens R, ed. 1976b. Pesticides in the environment: Vol 2.
New York: Marcel Dekker.
* White-Stevens R, ed. 1971. Pesticides in the environment: Vol 1. Part
1, Part 2. New York: Marcel Dekker.
*/- Worthing CR, Walker SB, eds. 1983. The pesticide manual -- a world
compendium. 7th ed. Lavenham, Suffolk, Great Britain: The Lavenham
Press Limited.
*. Worthing CR, ed. 1979. Pesticide manual. 6th ed. Worcestershire,
England: British Crop Protection Council.
/- Worthy-W. 1985. Methyl isocyanate: the chemistry of a hazard. Chem
Eng News 63(6):27-33.
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CAS Registry Number: 50-00-0
Page 5 of 5
FORMALDEHYDE
SECTION VIII (continued)
SUIT MATERIAL.PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl EXCELLENT/MANY
Butyl/Neoprene GOOD/LIMITED*
CPE GOOD/LIMITED
Neoprene POOR/MANY
Nitrile POOR/MANY
PE EXCELLENT/MANY
PVC POOR/MANY
Teflon POOR/LIMITED
Viton EXCELLENT/MANY
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
NOTES: For concentrations <37% formaldehyde
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 50-00-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
FORMALDEHYDE
(50-00-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas or liquid below -20 degrees C (-6 degrees F).
Odor - Strong, pungent.
Commercial Form - Aqueous solution containing approximately 40% formaldehyde
and 15% methanol.
Uses - Disinfectant, preservative, embalming fluid, treatment of grain smut,
hardening agent, reducing agent, corrosion inhibitor, gold and silver recovery,
textile manufacture.
Other Names - Formalin, formic aldehyde, Formol, Karsan, Lysoform, methanal,
methyl aldehyde, methylene oxide, Morbicid, oxomethane, oxymethylene.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's
lactate, sodium bicarbonate, dopamine, norepinephrine, levarterenol.
-------
EFATG
CAS Registry Number: 50-00-0
Page 2 of 3
FORMALDEHYDE
Signs and Symptoms of Acute Formaldehyde Exposure:
Acute exposure to formaldehyde may result in irritation or burns to the skin,
eyes, and mucous membranes; lacrimation (tearing); nausea; vomiting (may be
bloody); abdominal pain; and diarrhea. Difficulty in breathing, cough,
pneumonia, and pulmonary edema may occur. Sensitized people may experience
asthmatic reactions, even when exposed briefly. Hypotension (low blood
pressure) and hypothermia (reduced body temperature) may precede cardiovascular
collapse. Lethargy, dizziness, convulsions, and coma may be noted. Nephritis
(inflammation of the kidneys), hematuria (bloody urine), and liver toxicity
have been reported.
Emergency Life-Support Procedures:
Acute exposure to formaldehyde may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to formaldehyde.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to formaldehyde.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
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EFATG
CAS Registry Number: 50-00-0
Page 3 of 3
FORMALDEHYDE
5. Wash exposed skin areas twice with soap and water,
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of formaldehyde is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of formaldehyde may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 5.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities'of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. Transport to a health care facility.
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CAS Registry Number: 50-07-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MITOMYCIN C
CAS Registry Number: 50-07-7
Synonyms: Ametycine; Mutamycin; NSC-26980; Azirino[2',3':3,4]pyrrolo
[l,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-l,la,2,8,8a,8b-
hexahydro-8a-methoxy-5-methyl-,[laR-(la.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-
Chemical Formula: C15H18N4O5
Molecular Weight: 334.37
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
14 rag/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Above 680°F, 360°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Merck 1983)
Appearance and Odor: Blue-violet crystals (*Merck 1983)
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CAS Registry Number: 50-07-7
Page 2 of 3
MITOMYCIN C
i
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Toxic doses as low as 750
rag/kg have been reported in humans (*NIOSH 1979). The major toxic effect
is myelosuppression, characterized by marked leukopenia and
thrombocytopenia; this may be delayed and cumulative. Interstitial
pneumonia and glomerular damage resulting in kidney failure are unusual but
well documented complications (Oilman 1985, p. 1289).
Medical Conditions Generally Aggravated by Exposure: Lung conditions —
administration of mitomycin has been recognized as causing pneumonitis,
alveolitis and pulmonary fibrosis (*Weiss 1980). Kidney conditions --
administration of mitomycin can cause kidney damage (Oilman 1985, p. 1289).
Kidney toxicity was observed in 1-5 percent of patients. Depressed immune
conditions (*AMA 1977).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
- Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
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CAS Registry Number: 50-07-7
Page 3 of 3
MITOMYCIN C
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Anti-tumor antibiotic complex (*Merck 1976). This drug is usually injected
intravenously (*AMA 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact.
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Headaches, blurred vision, confusion,
drowsiness, fatigue, diarrhea, and pain have been occasionally noted.
These do not appear to be dose related by intravenous administration.
Fever and anorexia occur in 15 percent of patients. Hair loss, sloughing
of skin, and loss of feeling occur in approximately 4 percent of patients.
Labored breathing, cough and pneumonia occur in some cases. Renal toxicity
is sometimes observed (*AMA 1977).
Emergency and First Aid Procedures: Seek immediate medical care. Skin
decontamination should be thorough, with water and soap. Eye exposure can
be followed by irrigation of eyes with plain tap water (*Rumack 1975 to
Present). (Non-Specific - Medicines, n.o.s.) If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Remove
and isolate contaminated clothing and shoes at the site. Keep victim quiet
and maintain normal body temperature (DOT 1984, Guide 11).
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CAS Registry Number: 50-14-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ERGOCALCIFEROL
CAS Registry Number: 50-14-6
Synonyms: 9,10-Secoergosta-5,7,10(19),22-Tetraen-3-beta-ol;
9,10-Secoergosta-5,7,10( 19),22-Tetraen-3-ol,(3-beta,5Z,7E,22E)-; Activated
Ergosterol; Buco-D; Calciferol; Calciferon 2; Condacaps; Condocaps; Condol;
Crtron; Crystallina; D-Arthin; D-Tracetten; Daral; Davitamon D; Davitin; De-Rat
Concentrate; Decaps; Dee-Osterol; Dee-Ron; Dee-Ronal; Dee-Roual; Deltalin;
Deratol; Detalup; Diactol; Divit Urto; Doral; Drisdol;
Ergorone; Ergosterol Activated; Ergosterol, Irradiated; Ertron; Fortodyl;
Geltabs; Hi-Deratol; Infron; Irradiated Ergosta-5,7,22-Trien-
3-Beta-ol; Irradiated Ergosterol; Metadee; Mina D2; Mulsiferol; Mykostin;
Oleovitamin D; Oleovitamin D2; Ostelin; Radiostol; Radsterin; Shock-Ferol;
Vitamin D2
Chemical Formula: C28H44O
Molecular Weight: 396.63
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral (dog)
4 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 239-244°F, 115-118°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 50-14-6
Page 2 of 4
ERGOCALCIFEROL
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Merck 1976)
Appearance and Odor: White crystals, odorless (*Osol 1975)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Ergocalciferol poisoning
disturbs calcium metabolism and causes kidney damage (Buchel 1983, p. 224).
Ergocalcif erol in a single acute ingestion presents no toxic hazards.
Daily ingestion in excess of 5000 units/day in children or 7500 units/day
in adults will produce toxic symptoms associated with hypervitaminosis D
(*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Those with
hypercalcemia are at a greater risk (Physicians' Desk Reference 1985, p.
1748)
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Medicines, n.o.s.) Extinguish
with dry chemical, carbon dioxide, water spray, fog, or foam (DOT 1984,
Guide 11).
Special Fire Fighting Procedures: (Non-Specific — Medicines, n.o.s.)
Move container from fire area if you can do so without risk. Spray cooling
water on containers that are exposed to flames until well after fire is out
(DOT 1984, Guide 11).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 50-14-6
Page 3 of 4
ERGOCALCIFEROL
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Furia 1972)
Stable:
Conditions to Avoid: Shows signs of decomposition when stored for a
few days at room temperature (*Furia 1972).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Nutrient and/or dietary supplement food additive (*Sax 1975).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Medicines, n.o.s.) Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas.
Shut off ignition sources; no flares, smoking or flames in hazard
area. Keep combustibles (wood, paper, oil, etc.) away from
spilled material. Do not touch spilled material. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 11).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Initial symptoms of ergocalciferol
poisoning include anorexia, nausea and vomiting. It often mimics
hyperparathyroidism with thirst, muscular weakness, nervousness, kidney
impairment, hypertension (*Gosselin 1976), and excessive urination (*Gilman
1980).
-------
CAS Registry Number: 50-14-6
Page 4 of 4
ERGOCALCIFEROL
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific — Medicines, n.o.s.)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Remove and isolate contaminated clothing
and shoes at the site. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 11).
-------
CAS Registry Number: 50-00-0
Page 3 of 5
FORMALDEHYDE
SECTION IV (continued)
UEL: 73% (*Sax 1975)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog or foam. Move container
from fire area if you can do so without risk. Do not get water inside
container. Spray cooling water on containers exposed to flames until well
after fire is out. Withdraw immediately in case of rising sound from
venting safety device or any discoloration of tank due to fire (DOT 1984,
Guide 29).
Special Fire Fighting Procedures: Keep unnecessary people away; stay
upwind; keep out of low areas. Isolate for 1/2 mile in all directions if
tank car or truck is involved in fire (*DOT 1984). Wear self-contained
breathing apparatus; wear goggles if eye protection not provided. Shut off
flow of gas or liquid and keep cooling water streams on exposed tanks or
containers. Use water spray carefully in vicinity of dusts so as not to
create dust clouds (*NFPA 1978).
Unusual Fire and Explosion Hazards: Toxic vapors such as carbon dioxide
and carbon monoxide are generated during combustion (*Environment Canada
1982). Explosion hazard: when aqueous formaldehyde solutions are heated
above their flash points, a potential for explosion hazard exists. High
formaldehyde concentration or methanol content lowers flash point. Reacts
with nitrogen oxides at about 180; the reaction becomes explosive. Also
reacts violently with perchloric acid-aniline, performic acid,
nitromethane, magnesium carbonate, and hydrogen peroxide (Sax 1984, p.
1452).
NFPA Flammability Rating: 4 (gas); 2 (37% solution)
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes, aqueous solutions (*Lefaux 1968)
Stable: Yes, commercial formaldehyde-alcohol solutions
(*Kirk-Othmer 1978); gas is stable in absence of
water (*HeaIth and Safety Executive Monograph 1981)
Conditions to Avoid: Oxidizing and alkaline materials (*NFPA 1978)
Incompatibility (Materials to Avoid): Reacts with peroxide, nitrogen
oxide, and performic acid causing explosions (*Environment Canada 1982).
Can react with hydrogen chloride or other inorganic chlorides to form
bis-chloromethylether (BCME), a known carcinogen (*General Electric Co.
1981, MSDS 360). Very reactive, combines readily with many substances, 40%
solution is powerful reducing agent (*Merck 1976). Incompatible with
amines, azo compounds, dithiocarbamates, alkali and alkaline earth metals,
nitrides, nitro compounds, unsaturated aliphatics and sulfides, organic
peroxides, oxidizing agents, and reducing agents (*Environment Canada
1982).
Hazardous Decomposition or Byproducts: When heated, irritant formaldehyde
gas evolved from solution (Sax 1984, p. 1452). The main products of
-------
CAS Registry Number: 50-00-0
Page 4 of 5
FORMALDEHYDE
SECTION V (continued)
decomposition are carbon monoxide and hydrogen. Metals such as platinum,
copper, chromia, and alumina also catalyze the formation of methanol,
methylformate, formic acid, carbon dioxide, and methane (*Kirk- Othmer
1978).
Hazardous Polymerization: May Occur: Yes (*Environment Canada 1982)
May Not Occur:
Conditions to Avoid: Compound will polymerize with active organic
materials such as phenol (*General Electric Co. 1981, MSDS 360). Will
polymerize violently in the presence of caustics and nitrides; (amines)
exothermic reaction, (Azo compound) exothermic reaction giving off
nitrogen gas, (caustics) heat generation and violent polymerization,
(dithiocarbamates) formation of flammable gases and toxic fumes,
formation of carbon disulfide may result, (alkali and alkaline earth
metals) heat generation and formation of a flammable hydrogen gas
(*Environment Canada 1982).
SECTION VI - USE INFORMATION
Urea and melamine resins; polyacetal resins; phenolic resins; ethylene
glycol; pentaerythritol; hexamethylenetetramine; fertilizer; dyes, medicine
(disinfectant, germicide); embalming fluids; preservative; hardening agent;
reducing agent, as in recovery of gold and silver; corrosion inhibitor in
oil wells; durable-press treatment of textile fabrics; possible
condensation to sugars and other carbohydrates for food use (experimental);
industrial sterilant; treatment of grain smut (Hawley 1977, p. 395).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no flares, smoking or flames in hazard area. Do
not touch spilled material; stop leak if you can do so without risk. Use
water spray to reduce vapors; do not get water inside container. Small
spills: absorb with sand or other noncombustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 29). Use fluorocarbon water
spray, Cellosize, and Hycar to diminish vapors. Use sodium carbonate,
ammonium hydroxide or sodium sulfite to neutralize spill. Use universal
gel, fly/ash, universal sorbent material, or cement powder to absorb the
spill (*Environment Canada 1982).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 50-00-0
Page 1 of 5
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FORMALDEHYDE
CAS Registry Number: 50-00-0
Synonyms: BFV; FA; Fannoform; Formaldehyde solution; Formaldehyde, as
Formalin solution (DOT); Formaldehyde, gas; Formalin; Formalin 40; Formalith;
Formic Aldehyde; Formol; Fyde; Hoch; Ivalon; Karsan; Lysoform; Methanal; Methyl
Aldehyde; Methylene Glycol; Methylene Oxide; Morbicid; NCI-C02799; Oxomethane;
Oxymethylene; Superlysoform
Chemical Formula: CH2O
Molecular Weight: 30.03
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 1,000 (pounds) (statutory); 100 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -3.1°F, -19.5°C at 760 mmHg (*Merck 1976); commercial
aqueous formaldehyde boils at 205°F, 96°C (Merck 1983, p. 604)
Specific Gravity (H2O=1): 1.067 (*Merck 1976); 0.815 at -20°C/4°C for
anhydrous form (Merck 1983, p. 604)
Vapor Pressure (mmHg): 10 at -88°C (*Patty 1963), for anhydrous form
Melting Point: -134°F,-92°C (*Merck 1976), for anhydrous form
Vapor Density (AIR=1): 1.03 for aqueous solution; 1.075 for gas
(*Environment Canada 1982), 1.067 for gas (Merck 1983, p. 604)
-------
CAS Registry Number: 50-00-0
Page 2 of 5
FORMALDEHYDE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble in water, up to 55% (*Merck 1976)
Appearance and Odor: Gas or liquid, strong, pungent odor, clear,
water-white (Sax 1984, p. 145).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 3 ppm; Ceiling Concentration 5 ppm; Peak Concentration 10
ppm/30 minutes/8 hours (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 1.5 mg/ms (1 ppm) (*ACGIH 1980); STEL 3 mg/ms (2 ppm)
(ACGIH 1986-87, p.19)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 104)
Other Limits Recommended: Occupational exposure to formaldehyde
recommended standard -- air ceiling concentration 1.2 mg/m3/30 minutes
(*NIOSH/RTECS 1985). Industrial substance suspect of carcinogenic
potential for humans recommended standard 1 ppm (ACGIH 1984, p. 42)
Routes of Entry: Inhalation: Yes (Proctor and Hughes 1978,
pp. 272-273)
Skin: Yes (Environment Canada 1982)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): The probable oral lethal
dose for humans is 0.5-5 g/kg, or between 1 ounce and 1 pint for a 150
pound person (*Gosselin 1976). Acute -- below 1 ppm, odor perceptible to
most. 2-3 ppm, mild tingling of eyes. 4-5 ppm, increased discomfort, mild
lacrimation. 10 ppm, profuse lacrimation; can be withstood only for few
minutes. 10-20 ppm, breathing difficult, cough, severe burning of nose and
throat. 50-100 ppm, acute irritation of respiratory tract, very serious
injury likely. Skin — primary irritation from strong solutions, gas.
Delayed — sensitization dermatitis (Proctor and Hughes 1978, pp. 272-273).
Suspected carcinogen (*Kirk-Othmer 1978). Effects in women include
menstrual disorders and secondary sterility (*IARC 1972-1985). Solutions
splashed in eyes have caused injuries ranging from severe, permanent
corneal opacification and loss of vision to minor discomfort (*Grant 1974).
Medical Conditions Generally Aggravated by Exposure: In people sensitized
to formaldehyde, late asthmatic reactions may be provoked by brief
exposures at approximately 3 ppm (*Hendrick 1982).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 60°C/40% solution (*Merck 1976)
Flammable Limits:
LEL: 7% (*Sax 1975)
-------
CAS Registry Number: Not Found
Page 3 of 3
ORGANORHODIUM COMPLEX
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Catalyst (PMN-82-147).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poisonous Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do it
without risk. Small spills: take up with sand or other
non-combustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 55).
-------
CAS Registry Number: Not Found
Premanufacture Notice Number: PMN-82-147
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- GENERIC NAME: ORGANORHODIUM COMPLEX
(This chemical was identified from a Premanufacture Review Notice (PMN)
submitted to EPA. The submitter has claimed certain information on the
submission to be confidential, including specific chemical identity,
chemical formula, and molecular weight.)
CAS Registry Number: Not Found
Synonyms: Not Found
Chemical Formula: Not Found
Molecular Weight: Not Found
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.08 mg/liter (submitter's estimate) (PMN-82-147)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (PMN-82-147)
-------
CAS Registry Number: Not Found
Page 2 of 3
ORGANORHODIUM COMPLEX
SECTION II (continued)
Appearance and Odor: Green crystals (PMN-82-147)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Rhodium metal fume dust) 0.1 mg/ms, as rhodium (NIOSH 1987,
p. 204)
ACGIH TLV: (Insoluble Rhodium Compounds) TWA 1 mg/m3, as rhodium (A(
1984, p. 29)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific —
Organometals) Organometals may be highly toxic orally. They are
irritating to skin, eyes, and mucous membranes. They can damage lung
tissue and the liver (Sax 1984, p. 2095).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog or foam. Move container from fire area if you can do it
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific « Poisonous Solid,
n.o.s.) Stay upwind; keep out of low areas. Wear self-contained (positive
pressure if available) breathing apparatus and full protective clothing
(DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Poisonous Solid,
n.o.s.) Fire may produce irritating or poisonous gases (DOT 1984, Guide
53).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 51-21-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FLUOROURACIL
CAS Registry Number: 51-21-8
Synonyms: Uracil, 5-Fluoro-; 5-Fluorouracil; Efudex; Fluoroplex;
2,4-Dioxo-5-Fluoropyrimidine; 5-Fluoro-2,4( 1 H,3H)-Pyrimidinedione; 5-Fluoro-
2,4-Pyrimidinedione; 5-Fluoropyrimidine-2,4-Dione; 5-Fluoropyrimidine-
2,4-Dione; Fluoro Uracil; Fluracil; Fluril; FU; 5-FU; NSC 19893; RO 2-9757;
U-8953; 2,4(1 H,3H)-Pyrimidinedione, 5-Fluoro-
Chemical Formula: C4H3FN2O2
Molecular Weight: 130.08
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rabbit)
18.9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposes at 540-541°F, 282-283°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g in 80 mL of water (*Osol 1975)
-------
CAS Registry Number: 51-21-8
Page 2 of 4
FLUOROURACIL
SECTION II (continued)
Appearance and Odor: White to practically white crystalline powder;
practically odorless (*Osol 1975)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Physicians' Desk Reference 1980, p. 1452)
Ingestion: Yes (*Goodman 1975)
Health Hazards (Acute, Delayed, and Chronic): Minimum toxic dose in
humans is approximately 450 mg/kg (total dose) over 30 days for the
ingested drug. Intravenous minimum toxic dose in humans is a total dose
of 6 mg/kg over three days. Depression of white blood cells occurred
after intravenous administrative of a total dose of 480 mg/kg over 32
days (*NIOSH/RTECS 1978).
Medical Conditions Generally Aggravated by Exposure: Occasional
neuropathy and cardiac toxicity have been reported (Oilman 1985, pp.
1270-1271). Do not use during pregnancy (Physicians' Desk Reference 1980,
p. 1455). Patients with impaired hepatic or renal function, with a
history of high-dose pelvic irradiation or previous use of alkylating
agents should be treated with extreme caution (Physicians' Desk Reference
1980, p. 1455). Patients with nutritional deficiencies and protein deple-
tion have a reduced tolerance to fluorouracil (Oilman 1985, p. 1270).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Drugs or Medicines, n.o.s.
(Solid) Poison B) Extinguish fire using agent suitable for type of
surrounding fire (material itself burns with difficulty). Use water in
flooding quantities as fog. Use "alcohol" foam, carbon dioxide or dry
chemical (Student 1981, p. 215).
Special Fire Fighting Procedures: (Non-Specific ~ Drugs or Medicines,
n.o.s. (Solid) Poison B) Avoid breathing dusts, and fumes from burning
material. Keep upwind. Avoid bodily contact with the material. Wear
-------
CAS Registry Number: 51-21-8
Page 3 of 4
FLUOROURACIL
SECTION IV (continued)
boots, protective gloves, and goggles. Wear self-contained breathing
apparatus (Student 1981, p.-215).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Osol 1975)
Conditions to Avoid: Decomposing heat (*Merck 1976)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits very toxic fumes of
flourides and nitrogen oxides when heated to decomposition (Sax 1984, p.
1450).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Antineoplastic drug (*Merck 1976); chemosterilant for insects
(*White-Stevens 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Drugs) Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. If water
pollution occurs, notify appropriate authorities. Spill or leak:
shut off ignition sources; no flares, smoking or flames in hazard
area. Keep combustibles (wood, paper, oil etc.) away from spilled
material. Do not touch spilled material. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 11).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
-------
CAS Registry Number: 51-21-8
Page 4 of 4
FLUOROURACIL
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Loss of appetite and nausea are earliest
symptoms, with other symptoms of diarrhea, inflammation or sores in the
mouth, gastric burning, and intestinal discomfort. More serious symptoms
are due to the suppression of bone marrow, with decrease of white cell
count and blood platelets, and anemia. Hair loss, nail changes,
dermatitis, and pigmentation and atrophy of skin also occur (*Goodman
1975).
Emergency and First Aid Procedures: (Non-Specific -- Drugs) Move victim
to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Remove and isolate contaminated clothing
and shoes at the site. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 11).
-------
CAS Registry Number: 51-75-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MECHLORETHAMINE
CAS Registry Number: 51-75-2
Synonyms: 2,2'-Dichloro-N-Methyldiethylamine; 2-Chloro-N-(2-Chloroethyl)-
N-Methylethanamine; Beta,Beta'-Dichlorodiethyl-N-Methylamine; Bis(2-Chloro-
ethyl)Methylamine; Bis(Beta-Chloroethyl)Methylamine; Caryolysin; Chloramine
(the nitrogen mustard); Chlorethazine; Chlormethine; Di(2-Chloroethyl)
Methylamine; Dichlor Amine; Diethylamine, 2,2'-Dichloro-N-Methyl-; Embichin;
ENT-25294; Ethanamine, 2-Chloro-N-(2-Chloroethyl)-N-Methyl-; HN2; MBA;
Methylbis(2-Chloroethyl)Amine; Methylbis(Beta-Chloroethyl)Amine; Methylbis
(Chloroethylamine); Methyldi(2-Chloroethyl)Amine; Mustargen; Mustine;
N,N-Bis(2-Chloroethyl)methylamine; N,N-Di(Chloroethyl)Methylamine;
N-Methyl-2,2'-Dichlorodiethylamine; N-Methyl-bis(2-Chloroethyl)Amine;
N-Methyl-Bis(Beta-Chloroethyl)Amine; N-Methylbis(2-Chloroethyl)Amine;
N-Methylbis(Beta-Chloroethyl)Amine; Nitrogen Mustard; NSC 762; TL 146
Chemical Formula: C5HUC12N
Molecular Weight: 156.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin (rat)
14 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 189°F, 87°C at 18 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.118 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: -76°F, -60°C (*Merck 1976)
-------
CAS Registry Number: 51-75-2
Page 2 of 4
MECHLORETHAMINE
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very slightly soluble (*Merck 1976)
Appearance and Odor: Mobile liquid; faint odor of herring (*Merck 1976).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Gilman 1980)
Skin: Yes (*Gilman 1980)
Ingestion: Yes (*Gilman 1980)
Health Hazards (Acute, Delayed, and Chronic): Toxic doses as low as 400
mg/kg have been reported in humans (*NIOSH/RTECS 1985). Blood clots may
occur at site of intravenous injection and tissue damage if outside vein.
Powerful vesicant (causes blisters) when it contacts skin, mucous
membranes, or eyes. Delayed toxicity ~ missed menstrual periods, alopecia
(hair loss), hearing loss, tinnitus (ringing in ears), jaundice, impaired
spermatogenesis and germinal aplasia, swelling, and hypersensitivity
(*Gilman 1980).
Medical Conditions Generally Aggravated by Exposure: May damage fetus in
pregnant women (*Gilman 1980).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Poisonous Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Poisonous Liquid,
n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces
before entering them. Wear positive pressure breathing apparatus and
special protective clothing. Move container from fire area if you can do
so without risk. Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material (DOT 1984, Guide 55).
-------
CAS Registry Number: 51-75-2
Page 3 of 4
MECHLORETHAMINE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1976)
Stable:
Conditions to Avoid: Undiluted liquid decomposes on standing (*Merck
1976)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
Drug used in treatment of cancer (*Gilman 1980). Formerly used as a gas
warfare agent (*Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poisonous Liquid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 51-75-2
Page 4 of 4
MECHLORETHAMINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea and vomiting; bleeding; skin
lesions; menstrual irregularities (*Gilman 1980).
Emergency and First Aid Procedures: Treat symptoms using procedures for
general poison (*Rumack 1975 to Present). (Non-Specific -- Poisonous
Liquid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 51-83-2
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CARBACHOL CHLORIDE
CAS Registry Number: 51-83-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 917) Choline, Chloride,
Carbamate; Carbachol; Carbacholin; Carbacholine; Carbacholine Chloride;
Carbacolina; Carbamic Acid, Ester with Choline Chloride; Carbaminocholine
Chloride; Carbaminoylcholine Chloride; Carbamiotin; Carbamoylcholine Chloride;
gamma-Carbamoyl Choline Chloride; Carbamoylcholine-Hydrochloride;
Carbamylcholine Chloride; Carbochol; Carbocholin; Carbocholine; Carbyl;
Carcholin; Choline Carbamate Chloride; Choline, Chloride Carbamate(Ester);
Choline Chloride, Carbamoyl-; Choline Chlorine Carbamate; Coletyl; Doryl; Doryl
(Pharmaceutical); Ethanaminium, 2-((Aminocarbonyl)oxy)-N,N,N-Trimethyl-,
Chloride; (2-Hydroxyethyl)Trimethyl Ammonium Chloride Carbamate; Isopto
Carbachol; Jestryl; Lentin; Miostat; Mistura C; Moryl; P.V. Carbachol; TL 457;
Vasoperif
Chemical Formula: C6H15N2O2C1
Molecular Weight: 182.68
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 15 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 392-401°F, 200-205°C (Merck 1983, p. 245)
-------
CAS Registry Number: 51-83-2
Page 2 of 3
CARBACHOL CHLORIDE
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g/mL (Merck 1983, p. 245)
Appearance and Odor: Crystalline, odorless, but on standing in an open
container, develops a faint odor resembling that of an aliphatic amine
(Merck 1983, p. 245); hygroscopic prisms or powder (Weast 1979, p. C-246)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 631)
Ingestion: Yes (Sax 1984, p. 631)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by mouth (Sax
1984, p. 631).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: The aqueous solution is stable even when heated
(Merck 1983, p. 245).
-------
CAS Registry Number: 51-83-2
Page 3 of 3
CARBACHOL CHLORIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of chloride and nitrogen oxides (Sax 1984, p. 631).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Cholinergic; parasympathomimetic, used chiefly in large animals, especially
for colic in the horse (Merck 1983, p. 245)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid skin contact (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles foi additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
DOT 1984
Farm Chemicals Handbook 1984
Oilman 1985
Hayes 1982
Gosselin 1984
Buchel 1983
Clayton and Clayton 1981-82
Hawley 1981
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CAS Registry Number: 54-11-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- NICOTINE
CAS Registry Number: 54-11-5
Synonyms: (-)-3-(l-Methyl-2-Pyrrolidyl)Pyridine; l-Methyl-2-(3-Pyridyl)
Pyrrolidine; beta-Pyridyl-alpha-N-Methylpyrrolidine; Destruxol Orchid Spray;
EMO-NIK; ENT 3,424; Flux Maag; Fumetobac; L-3-(l-Methyl-2-Pyrrolidyl)Pyridine;
L-Nicotine; Mach-Nic; Niagara PA Dust; Nic-Sal; Nico-Dust; Nico-Fume; Nicocide;
Nicotin; Nicotine Alkaloid; Ortho N-4 Dust; Ortho N-5 Dust; Pyridine,
3-(l-Methyl-2-Pyrrolidinyl)-, (S)-; Pyridine, 3-(Tetrahydro-
l-Methylpyrrol-2-yl); Pyrrolidine, l-Methyl-2-(3-Pyridyl)-; Tendust;
Tetrahydronicotyrine, DL-
Chemical Formula: C10H14N2
Molecular Weight: 162.23
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: Not Found
TPQ: 100 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 476.1°F, 246.7°C at 745 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.0097 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at 61.8°C (Sax 1984, p. 1997)
Melting Point: -110°F, -79°C (*Weast 1979)
Vapor Density (AIR=1): 5.61 (Sax 1984, p. 1997)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible below 60°C (*Merck 1983)
-------
CAS Registry Number: 54-11-5
Page 2 of 4
NICOTINE
SECTION II (continued)
Appearance and Odor: Colorless to pale yellow, oily liquid (*Merck 1983).
Slight, fishy odor when warm (NIOSH/OSHA 1978, pp. 138-139).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.5 mg/ms (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.5 mg/ms (skin) (*ACGIH 1983)
IDLH: 35 mg/ms (NIOSH/OSHA 1978, p. 138-139)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1997)
Skin: Yes (Merck 1983, p. 935)
Ingestion: Yes (Sax 1984, p. 1997)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste
(less than 7 drops) for a 70 kg (150 Ibs.) person (*Gosselin 1976). It may
be assumed that ingestion of 40-60 mg of nicotine is lethal to humans.
There is fundamental difference between acute toxicity from use of nicotine
as insecticide or from ingestion, and chronic toxicity that may be caused
by prolonged exposure to small doses as occurs in smoking (*Encyc Occupat
Health and Safety 1983). Maternal smoking during pregnancy is associated
with increased risk of spontaneous abortion, low birth weight and
still-birth (*The Chemical Society 1975). Nicotine was found as a
co-carcinogen in animals (*NRC 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Low fire hazard when exposed to heat or flame (Sax
1984, p. 1997)
LEL: 0.75% (Sax 1984, p. 1997)
UEL: 4.0% (Sax 1984, p. 1997)
Extinguishing Methods: Extinguish with alcohol foam, dry chemical, or
carbon dioxide (Sax 1984, p. 1997). Water may cause frothing if it gets
below surface of liquid and turns to steam. However, water fog gently
applied to surface will cause frothing which will extinguish the fire
(*NFPA 1978).
Special Fire Fighting Procedures: Material too dangerous to health to
expose firefighters. A few whiffs of the vapor could cause death; vapor or
liquid could be fatal on penetrating firefighter's normal full protective
clothing. Normal full protective clothing and breathing apparatus
available to the average fire department will not provide adequate
protection against inhalation or skin contact (*NFPA 1978).
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CAS Registry Number: 54-11-5
Page 3 of 4
NICOTINE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: There is a moderate explosion hazard
when exposed to heat or flame (.Sax 1984, p. 1997).
NFPA Flammability Rating: 1
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (normal conditions) (*NFPA 1978)
Conditions to Avoid: Heat or flames (*Sax 1975)
Incompatibility (Materials to Avoid): Avoid oxidizing materials (Sax
1984, p. 1997).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits nitrogen oxides, carbon monoxide and other highly toxic fumes (Sax
1984, p. 1997).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as an insecticide, fumigant and in veterinary matters as an
ectoparasiticide and anthelmintic (*Merck 1983). Also, used in tanning
(*NRC 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
The normal full protective clothing and breathing apparatus available to
the average fire department will not provide adequate protection against
inhalation or skin contact with this material (*NFPA 1978). Do not touch
spilled material; stop leak; reduce vapors with water spray. Small Spills:
take up with sand or other noncombustible absorbent material and place
into containers for later disposal. Small Dry Spills: with clean shovel
place material into clean, dry container and cover; move containers from
spill area. Large Spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
-------
CAS Registry Number: 54-11-5
Page 4 of 4
NICOTINE
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 54-11-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
NICOTINE
(54-11-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to pale yellow oily liquid; brown on exposure to air.
Odor - Slightly fishy odor when warm.
Commercial Forms - 93 to 98% pure liquid; 3 to 5% dust.
Uses - Insecticide, fumigant, veterinary medicine, tanning.
Other Names - Black Leaf 40, Destruxol Orchid Spray; Futemobac; Nico-dust;
Nico-Fume; Ortho N-4 Dust; Ortho N-5 Dust; (S)-3-(l-methyl-2-pyrrolidinyl)
pyridine; Tendust.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, atropine.
Signs and Symptoms of Acute Nicotine Exposure:
Warning: Seizures may be rapid in onset. Caution is advised.
Acute exposure to nicotine may result in headache, dizziness, confusion,
agitation, restlessness, lethargy, seizures, and coma. Victims may experience
hypertension (high blood pressure), tachycardia (rapid heart rate), and
tachypnea (rapid respirations), followed by hypotension (low blood pressure),
bradycardia (slow heart rate), and respiratory depression. Cardiac arrhythmias
may also occur.
-------
EFATG
CAS Registry Number: 54-11-5
Page 2 of 3
NICOTINE
Gastrointestinal effects include nausea, vomiting, abdominal pain or burning
sensation, and diarrhea. Increased salivation, lacrimation (tearing), and
sweating may be noted.
Emergency Life-Support Procedures:
Acute exposure to nicotine may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to nicotine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to nicotine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 54-11-5
Page 3 of 3
NICOTINE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. RUSH to a health care facility.
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CAS Registry Number: 54-62-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- AMINOPTERIN
CAS Registry Number: 54-62-6
Synonyms: (NIOSH/RTECS 1983, Synonyms, Volume 2, p. 375) Glutamic Acid,
N-(p-(((2,4-Diamino-6-Pteridinyl)Methyl)Amino)Benzoyl)-, L-;
4-Amino-4-Deoxypteroylglutamate; 4-Amino-PGA; Aminopteridine;
4-Aminopteroylglutamic Acid; A-Ninopterin; APGA; N-(4-((2,4-Diamino-6-
Pteridinyl)Methyl)Amino)Benzoyl)-L-Glutamic Acid; ENT-26079; Folic Acid,
4-Amino-; NSC 739; L-GIutamic Acid, N-[4-[(Diamino-6-Pteridinyl)Methyl]
Amino]Benzoyl]-
Chemical Formula: C19H2oN8O5
Molecular Weight: 440.47
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD,0 oral (rat)
2.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 54-62-6
Page 2 of 3
AMINOPTERIN
SECTION II (continued)
Appearance and Odor: Clusters of yellow needles (Hawley 1981, p. 55)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Hawley 1981, p. 55)
Health Hazards (Acute, Delayed, and Chronic): An antimetabolite;
antagonizes the utilization of folic acid by the body. Highly toxic by
ingestion (Hawley 1981, p. 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
-------
CAS Registry Number: 54-62-6
Page 3 of 3
AMINOPTERIN
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Rodenticide (Merck 1983, pp. 70-71); medicine and rodenticide (Hawley
1981, p. 55). Not registered as a rodenticide in the U.S. (USEPA/Active
Ingredients 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove
and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
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CAS Registry Number: 55-91-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ISOFLUORPHATE
CAS Registry Number: 55-91-4
Synonyms: Diisopropyl Fluorophosphate; DFP; Diflupyl; Diflurphate;
Diisopropoxyphosphoryl Fluoride; Diisopropyl Fluorophosphonate; Diisopropyl
Phosphofluoridate; Diisopropyl Phosphorofluoridate; Diisopropylfluoro-
phosphate; Diisopropylfluorophosphoric Acid Ester; Diisopropylphosphoro-
fluoridate; Dyflos; Dyphlos; Floropryl; Fluophosphoric Acid, Diisopropyl Ester;
Fluorodiisopropyl Phosphate; Fluostigmine; Fluropryl; Isofluro- phosphate;
Isopropyl Fluophosphate; Isopropyl Phosphorofluoridate; Neoglaucit;
O,O'-Diisopropyl Phosphoryl Fluoride; O,O,-Diisopropyl Fluorophosphate; PF-3;
Phosphorofluoridic Acid, Bis(l-Methylethyl) Ester; Phosphorofluoridic Acid,
Diisopropyl Ester; T-1703; TL 466; Fluorophosphoric Acid, Diisopropyl Ester;
Fluoropryl; Isofluorophate; Isoflurophate
Chemical Formula: C6H14FO3P
Molecular Weight: 184.15
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.36 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 144°F, 62°C at 9 mmHg (*Merck 1983)
Specific Gravity (H2O=1): 1.055 (*Merck 1983)
Vapor Pressure (mmHg): 0.579 at 20°C (*Merck 1983)
Melting Point: -116°F, -82°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 55-91-4
Page 2 of 4
ISOFLUORPHATE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1.54% by weight at 25°C (*Merck 1983)
Appearance and Odor: Oily liquid ("Hawley 1981). Clear, colorless or
faintly yellow liquid (*Osol 1980).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Merck 1983)
Skin: Yes (Sax 1984, p. 1667)
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): This is an organophosphate
pesticide (*Morgan 1982). Extremely toxic: probable oral lethal dose in
humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful for 70 kg person
(150 Ib.) (*Gosselin 1984). The material is a cholinesterase inactivator.
Even traces of the vapor cause pinpoint pupils (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
• ' UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorous Pesticide,
n.o.s.) Dry chemical, carbon dioxide, water spray, or foam. For large
fires, water spray, fog, or foam. Fight fire from maximum distance. Dike
fire control water for later disposal (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear positive pressure breathing apparatus and special protective clothing
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: May burn but will not ignite readily.
Container may explode in heat of fire. Fire and runoff from fire control
water may produce irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 55-91-4
Page 3 of 4
ISOFLUORPHATE
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1983)
Conditions to Avoid: Forms hydrofluoric acid in presence of moisture
(*Merck 1983). Keep away from sources of heat (*Farm Chemicals
Handbook 1984). Anhydrous compounds or oil solutions are stable in
glass containers at room temperature (*Merck 1983).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Forms hydrogen fluoride in
presence of moisture; decomposes in water at pH about 2.5 (*Merck 1983).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Research tool in neuroscience for its ability to inhibit cholinesterase (by
phosphorylation) on an acute/sub-acute basis and to produce a delayed
neuropathy (*Peer Review Committee). An insecticide. Used in Germany as a
basis for "nerve gases" (Sax 1984, p. 1667).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
When handling in open containers, protect the eyes, nose, and mouth with a
suitable mask, and avoid contact with skin (*Osol 1980).
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material.
Use water spray to reduce vapors. Take up small spills with sand or other
noncombustible absorbent material and place in containers for later
disposal. Dike far ahead of large spills for later disposal (DOT 1984,
Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 55-91-4
Page 4 of 4
ISOFLUORPHATE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Respiration depression, muscle weakness,
twitching, and convulsions. Sweating, visual disturbances, vomiting,
diarrhea, chest and abdominal distress, and sometimes pulmonary edema
(*Morgan 1982).
Emergency and First Aid Procedures: Do not inhale vapors; avoid contact
with skin (*Merck 1983). (Non-Specific — Organophosphorous Pesticide,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal boc
temperature. Effects may be delayed; keep victim under observation (DO'
1984, Guide 55).
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CAS Registry Number: 56-25-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CANTHARIDIN
CAS Registry Number: 56-25-7
Synonyms: 7-Oxabicyclo[2.2.1 ]Heptane-2,3-Dicarboxylic Anhydride,
2,3-Dimethyl-; l,2-Dimethyl-3,6-Epoxyperhydrophthalic Anhydride;
4,7-Epoxyisobenzofuran-l,3-Dione, Hexahydro-3a,7a-Dimethyl-, (3a alpha, 4 beta,
7 beta, 7a alpha)-; 2,3-Dimethyl-7-Oxabicyclo[2.2.1]Heptane-2,3- Dicarboxylic
Anhydride; CAN; Cantharides Camphor; Cantharidine; Cantharone;
Exo-l,2-cis-Dimethyl-3,6-Epoxyhexahydrophthalic Anhydride; Hexahydro-3a alpha,
7a alpha-Dimethyl-4 beta, 7 beta-Epoxyisobenzofuran-l,3-dione; Kantaridin
Chemical Formula: C10H12O4
Molecular Weight: 196.21
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlo oral (hu-
man) 0.428 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Sublimes at 230°F, 110°C (Merck 1983, p. 242)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 424°F, 218°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in cold water (*Merck 1976); somewhat
-------
CAS Registry Number: 56-25-7
Page 2 of 3
CANTHARIDIN
SECTION II (continued)
soluble in hot water (*Merck 1976).
Appearance and Odor: Brown to black powder (Sax 1984, p. 627);
orthorhombic plates, scales (Merck 1983, p. 242).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Arena 1979)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste
of less than 7 drops for a 70 kg (150 Ib.) person (*Gosselin 1976). It is
very toxic by absorption through skin (*Merck 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 56-25-7
Page 3 of 3
CANTHARIDIN
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits acrid smoke and irritating fumes (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Formerly used as a counter-irritant and vesicant (*IARC 1972-1985). Also
used for the removal of benign epithelial growth, e.g., warts (*Gilman
1980). Used as an experimental antitumor agent. Active ingredient in
Spanish fly, a reputed aphrodisiac (*Peer Review Committee).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms from ingestion include vomiting,
abdominal pain, shock, bloody diarrhea, pain in throat and stomach,
swelling and blistering of tongue, difficulty swallowing, salivation, slow
and painful urination, and thirst. There may be delirium, fainting, and
tetanic convulsions (*Goodman 1975, *Rumack 1975 to Present, *Arena 1979,
*Gosselin 1976). Eye contact results in irritation with much swelling of
the lids (*Grant 1974). Initial tissue reaction upon contact with the skin
is swelling followed by blister formation within 24 hours (*Doull 1980).
Emergency and First Aid Procedures: For ingestion, induce vomiting with
syrup of ipecac. For skin contact thoroughly wash contaminated area with
soap and water. Eyes should be irrigated with plain tap water (*Rumack
1975 to Present).
-------
CAS Registry Number: 56-38-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PARATHION
CAS Registry Number: 56-38-2
Synonyms: Phosphorothioic Acid, O,O-DiethyI O-(p-Nitrophenyl) Ester (Liquid
Mixture); Parathion liquid; Alkron; Aileron; American Cyanamid 3422; Aphamite;
Bayer E-605; Bladan; Diethyl 4-Nitrophenyl Phosphorothionate; Diethyl
p-Nitrophenyl Thionophosphate; Diethyl Parathion; Diethyl-p-Nitrophenyl
Monothiophosphate; DNTP; E 605; ENT 15,108; Ethyl Parathion; Etilon; Folidol;
Fosferno; Fostox; Genithion; NA 2783 (DOT); NCI-C00226; Niran; Nitrostigmine;
O,O-Diethyl O-(p-Nitrophenyl) Phosphorothioate; O,O-Diethyl O-(p-nitrophenyl)
Thionophosphate; O,O-Diethyl O-4-Nitrophenyl Thiophosphate; O,O-Diethyl O-p-
Nitrophenyl Phosphorothioate; Oleoparathion; Panthion; Paraflow; Paramar;
Paraphos; Parawet; Phenphos; Phoskil; Phosphenol; Phosphorothioic Acid
O,O-Diethyl O-(4-Nitrophenyl) Ester; Rhodiatox; SNP; Stathion; Sulphos;
Thiophos; Vapophos
Chemical Formula: C10H14NO5PS
Molecular Weight: 291.27
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.084 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 707°F, 375°C (*Merck 1983)
Specific Gravity (H2O=1): 1.26 (*Merck 1983)
Vapor Pressure (mmHg): 0.0000378 at 20°C (*Worthing 1979)
Melting Point: 43°F, 6°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 56-38-2
Page 2 of 4
PARATHION
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble; 12.4 mg/liter at 20°C
(*Bowman 1979)
Appearance and Odor: Pale yellow liquid; technical grade is brown and has
a garlic-like odor (*Worthing 1979).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 mg/m3 (NIOSH 1978, p. 148)
ACGIH TLV: TWA 0.1 mg/ms (skin) (ACGIH 1986-87, p.26)
IDLH: 20 mg/m3 (*Encyc of Occupat Health and Safety 1983)
Other Limits Recommended: NIOSH: 0.05 mg/m3, 10 hour TWA (NIOSH 1987,
p. 184)
Routes of Entry: Inhalation: Yes (*Gosselin 1976)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose is 5-50 mg/kg, or between 7 drops and
1 teaspoonful for a 150-lb. person. As little as 1 drop can endanger life
if splashed in the eye. Toxicity is highest by inhalation (*Gosselin
1976).
Medical Conditions Generally Aggravated by Exposure: People at special
risk are those with a history of glaucoma, cardiovascular disease, hepatic
disease, renal disease, or central nervous system abnormalities (*Encyc
Occupat Health and Safety 1983).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 248-320°F, 120-160°C (Method not given)
(*Clayton and Clayton 1981-82)
Flammable Limits: Not highly flammable (*Encyc Occupat Health and Safety
1971)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water spray, dry chemical, foam, or carbon
dioxide (*NFPA 1978).
Special Fire Fighting Procedures: Use water spray to keep fire-exposed
-------
CAS Registry Number: 56-38-2
Page 3 of 4
PARATHION
SECTION IV (continued)
containers cool. If a leak or spill has not ignited, use water spray to
disperse vapors and to provide protection for firefighters. Water spray
may be used to flush spills away from exposures. Fight advanced or massive
fires from a safe distance or from a protected location. Special
protective clothing should be worn; normal protective clothing may be
penetrated (*NFPA 1978).
Unusual Fire and Explosion Hazards: When heated to decomposition, it can
emit toxic fumes of oxides of nitrogen, phosphorus, and sulfur. High
pressure hoses may scatter material from broken containers (*NFPA 1978).
Containers may explode when heated (*CHRIS 1978).
NFPA Flammability Rating: 1
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, in distilled water and in acid solution
(*Hawley 1981)
Conditions to Avoid: Store below 25-30°C (*Farm Chemicals Handbook
1983). It slowly decomposes in air and hydrolyzes in the presence of
alkaline material (*Hawley 1981). Containers may explode when heated
(*CHRIS 1978).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, the
material can emit toxic fumes of oxides of nitrogen, phosphorus, and sulfur
(*NFPA 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
This material is used as an insecticide (*SRI) and is used almost
exclusively in agriculture (Hayes 1982, p. 379).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of leaks or spills, special protective clothing should be worn.
Use water spray to disperse vapors and flush spills away (*NFPA 1978).
Ventilate area of spill or leak. Spills may be absorbed in vermiculite,
dry sand, earth, or a similar material (*NIOSH/OSHA 1981).
-------
CAS Registry Number: 56-38-2
Page 4 of 4
PARATHION
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 56-38-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
PARATHION
(56-38-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Pale yellow or brown liquid.
Odor - Garliclike (commercial form).
Commercial Form - Deep brown liquid in tins and steel drums.
Use - Pesticide.
Materials to Avoid - Alkali, strong oxidizers.
Other Names - Alkron; Aileron; DNTP; ethyl parathion; Etilon; Folidol;
Fosferno; Fostex; Genithion; Niran; Nitrostigmine; Oleoparathion; Paraflow;
Paramar; Paraphos; Parawet; Phoskil; Phosphenol; phosphorothioic acid, O,O-
diethyl O-(p-nitrophenyl) ester; Rhodiatox; Stathion; Thiophos; Vapophos.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Parathion Exposure:
Caution: Parathion is a cholinestorase inhibitor. It has been reported that
as little as one drop of parathion can endanger life if splashed in the eye.
Toxicity is highest by inhalation.
Acute exposure to parathion may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
-------
EFATG
CAS Registry Number: 56-38-2
Page 2 of 3
PARATHION
The heart rate may decrease following oral exposure or increase following
dermal exposure. Hypotension (low blood pressure) is not uncommon.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
Emergency Life-Support Procedures:
Acute exposure to parathion may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to parathion.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to parathion.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
-------
EFATG
CAS Registry Number: 56-38-2
Page 3 of 3
PARATHION
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of parathion is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of parathion may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 56-72-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- COUMAPHOS
CAS Registry Number: 56-72-4
Synonyms: 3-Chloro-4-Methyl-7-Coumarinyl Diethyl Phosphorothioate;
3-Chloro-4-Methyl-7-Hydroxycoumarin Diethyl Thiophosphoric Acid Ester;
3-Chloro-4-Methylumbelliferone O-Ester with O,O-Diethyl Phosphorothioate;
3-Chloro-7-Hydroxy-4-Methyl-Coumarin O,O-Diethyl Phosphorothioate; 3-Chloro-
7-Hydroxy-4-Methyl-Coumarin O-Ester with O,O-Diethyl Phosphorothioate; Agridip;
Asunthol; Asuntol; Azunthol; Bay 21/199; Bayer 21/199; Baymix; Baymix 50;
Co-Ral; Coumafos; Coumarin, 3-Chloro-7-Hydroxy-4-Methyl-, O-Ester with
O,O-Diethyl Phosphorothioate; Diethyl 3-Chloro-4-Methylumbelliferyl
Thionophosphate; Diethyl Thiophosphoric Acid Ester of 3-Chloro-4-Methyl-
7-Hydroxycoumarin; Diolice; ENT 17,957; Meldane, Meldone, Muscatox, NCI-C08662;
O,O-Diethyl 3-Chloro-4-Methyl-7-Umbelliferone Thiophosphate; O,O-Diethyl
O-(3-Chloro-4-Methyl-2-Oxo-2H-Benzopyran-7-yl) Phosphorothioate; O,O-Diethyl
O-(3-Chloro-4-Methyl-7-Coumarinyl) Phosphorothioate; O,O-Diethyl
O-(3-Chloro-4-Methylcoumarinyl-7) Thiophosphate; O,O-Diethyl
O-(3-Chloro-4-Methylumbelliferone) Thiophosphate; O,O-Diethyl O-(3-Chloro-4-
Methylumbelliferyl) Phosphorothioate; O-3-Chloro-4-Methyl-7-Coumarinyl
O,O-Diethyl Phosphorothioate; Phosphorothioic Acid, O,O-Diethyl Ester, O-Ester
with 3-Chloro-7-Hydroxy-4-Methylcoumarin; Phosphorothioic Acid, O-(3-Chloro-
4-Methyl-2-Oxo-2H-l-Benzopyran-7-yl) O,O-Diethyl Ester; Resistox; Resitox;
Suntol; Umbethion
Chemical Formula: C14H16C1O5PS
Molecular Weight: 362.78
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.303 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
-------
CAS Registry Number: 56-72-4
Page 2 of 4
COUMAPHOS
SECTION II (continued)
Specific Gravity (H2O=1): 1.31 at 25°C (*Spencer 1973)
Vapor Pressure (mmHg): 0.0000001 at 20°C (*Spencer 1973)
Melting Point: 196°F; 91°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Merck 1983)
Appearance and Odor: Slightly brownish crystals (*Merck 1983). Slight
odor of sulfur compound (*CHRIS 1978)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Very toxic, probable oral
lethal dose is 50-500 mg/kg, or between 1 teaspoonful and 1 oz. for a 70 kg
(150 Ib.) person (*Gosselin 1976). May be fatal if inhaled, swallowed, or
absorbed through skin. Contact may cause burns to skin and eyes (*DOT
1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE .AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material may burn but does not ignite easily
(*DOT 1984). Extinguish with water, foam, carbon dioxide, or dry chemicals
(*CHRIS 1978)
Special Fire Fighting Procedures: Use organic vapor respirator, rubber
gloves, and goggles (*CHRIS 1978). Dike fire control water for disposal
later (*DOT 1984).
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CAS Registry Number: 56-72-4
Page 3 of 4
COUMAPHOS
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Toxic and irritating oxides of sulfur
and phosphorus may form in fire (*CHRIS 1978).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Stable in water (*Merck 1983)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Incompatible with piperonyl
butoxide (*Farm Chemicals Handbook 1983)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of sulfur oxides, phosphorus oxides, and chlorides
(Sax 1984, p. 726)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
For control of a wide variety of livestock insects including cattle grubs,
lice, scabies, flies, and ticks; the common ectoparasites of sheep, goats,
horse, swine, and poultry as well as for screwworms in all these animals
(Farm Chemicals Handbook 1983, p. C61).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel, place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 56-72-4
Page 4 of 4
COUMAPHOS
*
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 56-72-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
COUMAPHOS
(56-72-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystals.
Odor - Slightly sulfurous.
Commercial Forms - 1 and 5% pure dusts, 3% pure spray foam, 5 to 50% pure
slightly brownish crystals, 25% pure wettable powder.
Use - Veterinary insecticide.
Other Names - Agridip; Asuntol; 3-chloro-4-methyl-7-coumarinyl diethyl
phosphorothioate; Co-Ral; Coumafos; Meldane; Muscatox; Negasunt; Resistox;
Suntol; Umbethion.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Coumaphos Exposure:
Note: Coumaphos is a cholinesterase inhibitor.
Acute exposure to coumaphos may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) and chest pain may
be noted. Hypertension (high blood pressure) is not uncommon. Respiratory
effects include dyspnea (shortness of breath), respiratory depression, and
respiratory paralysis. Psychosis may occur.
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CAS Registry Number: 56-72-4
Page 2 of 3
COUMAPHOS
Emergency Life-Support Procedures:
Acute exposure to coumaphos may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to coumaphos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to coumaphos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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CAS Registry Number: 56-72-4
Page 3 of 3
COUMAPHOS
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of coumaphos is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of coumaphos may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainly exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 57-14-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ DIMETHYLHYDRAZINE
CAS Registry Number: 57-14-7
Synonyms: As-Dimethylhydrazine; Asym Dimethylhydrazine; Asymmetric
Dimethylhydrazine; Dimazin; Dimazine; 1,1-Dimethylhydrazine; Dimethylhydrazine
Unsymmetrical; DMH; Hydrazine, 1,1-Dimethyl; N,N-Dimethylhydrazine;
U-Dimethylhydrazine; UDMH; Uns-Dimethylhydrazine; Unsym-Dimethylhydrazine;
Unsymmetrical-Dimethylhydrazine
Chemical Formula: C2H8N2
Molecular Weight: 60.10
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mus) 0.422 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 147°F, 63.9°C at 760 mmHg (*Merck 1983)
Specific Gravity (H2O=1): 0.7914 at 220C/4°C (*IARC 1972-1985)
Vapor Pressure (mmHg): 157 mmHg at 25°C (Sax, 1986, p.65)
Melting Point: -72°F, -58°C (*Merck 1983)
Vapor Density (AIR=1): 1.94 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (*Encyc Occupat Health and Safety 1983)
Appearance and Odor: Clear, colorless liquid with characteristic
ammonia-like fish odor (*IARC 1972-1985). ;:
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CAS Registry Number: 57-14-7
Page 2 of 4
DIMETHYLHYDRAZINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 mg/m8, (0.5 ppm) (NIOSH 1987, p.108)
ACGIH TLV: TWA 1 mg/ms, (0.5 ppm) (skin) (ACGIH 1986-87, p.17)
IDLH: 50 ppm (NIOSH/OSHA 1978, p. 88)
Other Limits Recommended: NIOSH: 0.15 mg/ms, 120 minute ceiling (NIOSH
1987, p.108). Industrial substance suspect of carcinogenic potential for
humans (ACGIH 1983, p. 43). SPEGL 0.24 ppm (60 minutes) (NRC 1985b, pp.
37-48).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
.Health Hazards (Acute, Delayed, and Chronic): This compound exhibits high
acute toxicity as a result of exposure by all routes. Death or permanent
injury may result after very short exposure to small quantities (*Sax
1975). Chronic exposure may cause pneumonia, liver damage, and kidney
damage (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 5°F, -15°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 2% (*Sax 1979)
UEL: 95% (*Sax 1979)
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray, or
foam for small fires (*DOT 1984). In large fires water fog, carbon
dioxide, and bicarbonate agents may allow flashback and explosive
re-ignition (*CHRIS 1978).
Special Fire Fighting Procedures: Move containers from fire area if it
can be done without risk. Dike fire control water for later disposal, do
not scatter the material. Cool containers that are exposed to flames with
water until well after fire is out, wear positive pressure breathing
apparatus and special protective clothing. Isolate for one-half mile in
all directions if tank car or truck is involved in fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Vapor may explode if ignited in an
enclosed area (*CHRIS 1978). Vapors may travel to a source of ignition and
flashback. Runoff to sewer may create fire or explosion hazard (*DOT
1984).
NFPA Flammability Rating: 3
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CAS Registry Number: 57-14-7
Page 3 of 4
DIMETHYLHYDRAZINE
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (NFPA .1984, p. 325M-43)
Conditions to Avoid: Dangerous when exposed to heat, flame, or
oxidizers (*Sax 1979).
Incompatibility (Materials to Avoid): Dissolves, swells, and
disintegrates many plastics (*CHRIS 1978).
Hazardous Decomposition or Byproducts: When it decomposes,
1,1-dimethylhydrazine gives off toxic nitrogen compound fumes (*Rumack 1975
to Present).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 364)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Major uses include: chemical synthesis; stabilizer for organic peroxide
fuel additives; absorbent for acid gases; photography (*Hawley 1977); base
in rocket fuel formulations (*Merck 1983); stabilizer for plant growth
regulator (*Clayton and Clayton 1981-82).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources. Do not touch spilled material. Stop leak if
this can be done without risk. Use water spray to reduce vapors. Take up
small spills with sand or other non-combustible absorbent material and
place into containers for later disposal. Dike far ahead of large spills
for later disposal (*DOT 1984). Spills also may be removed with an
aspirator. Transfer to glass container and neutralize with dilute sulfuric
acid. Drain with copious amounts of water (*Rumack 1975 to Present).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 57-14-7
Page 4 of 4
DIMETHYLHYDRAZINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl EXCELLENT/MANY
Butyl/Neoprene POOR/LIMITED*
CPE POOR/LIMITED
Chlorobutyl GOOD/LIMITED
Neoprene POOR/MANY
Nitrile POOR/MANY
PVC POOR/MANY
Teflon POOR/LIMITED
Viton POOR/LIMITED
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 57-14-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIMETHYLHYDRAZINE
(57-14-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Clear, colorless liquid.
Odor - Ammonialike.
Commercial Form - 98% pure liquid in drums or tank cars.
Uses - Chemical synthesis, stabilizer for organic peroxide rocket fuel
formulations, acid gas absorbent, plant growth regulator, photography.
Materials to Avoid - Oxidizers.
Caution: Highly flammable. Avoid sources of extreme heat or ignition
including sparks or fire. Dimethylhydrazine will emit toxic nitrogen compounds
when heated to decomposition.
Other Names - Asym dimethylhydrazine, Dimazin, 1,1-dimethylhydrazine, UDMH.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbital, pyridoxine.
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CAS Registry Number: 57-14-7
Page 2 of 3
DIMETHYLHYDRAZINE
Signs and Symptoms of Acute Dimethylhydrazine Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and symptoms of acute exposure to dimethylhydrazine may include eye
irritation, facial numbness, facial swelling, and increased salivation.
Headache, twitching, seizures, convulsions, and coma may also occur.
Gastrointestinal effects include anorexia, nausea, and vomiting. Pulmonary
edema and hypotension (low blood pressure) are common. Dimethylhydrazine is
toxic to the liver, ruptures red blood cells, and may cause kidney damage.
Dermal contact may result in strong skin and mucous membrane irritation.
Emergency Life-Support Procedures:
Acute exposure to dimethylhydrazine may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as dimethylhydrazine-resistant sheeting and
disposable bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dimethylhydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dimethylhydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
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CAS Registry Number: 57-14-7
Page 3 of 3
DIMETHYLHYDRAZINE
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of dimethylhydrazine is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of dimethylhydrazine may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 57-24-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - STRYCHNINE
CAS Registry Number: 57-24-9
Synonyms: Certox; Dolco Mouse Cereal; Kwik-Kil; Mole Death; Mouse-Nots;
Mouse-Rid; Mouse-Tox; Pied Piper Mouse Seed; Ro-Dex; Sanaseed; Strychnos;
Strychnidin-10-one; Strychnin
Chemical Formula: C21H22N2O2
Molecular Weight: 334.40
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (mus)
2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 518°F, 270°C at SmmHg (*Merck 1983)
Specific Gravity (H2O=1): 1.36 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): Not Found
Melting Point: 514-554°F, 268-290°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g in 6400 ml (*Merck 1983).
Appearance and Odor: Colorless, transparent crystals or white crystalline
powder; odorless (*Osol 1980).
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CAS Registry Number: 57-24-9
Page 2 of 3
STRYCHNINE
*
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 0.15 mg/ms (NIOSH 1987, p. 210)
ACGIH TLV: TWA 0.15 mg/ms (ACGIH 1986-87, p. 29)
IDLH: 3 mg/ms (NIOSH/OSHA 1978, p. 168)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Not Found
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Super toxic; probable oral
lethal dose in humans is less than 5 mg/kg, a taste (less than 7 drops) for
a 70 kg (150 Ib.) person. It causes violent generalized convulsions.
Death results from respiratory arrest as the respiratory muscles are in
sustained spasm (*Gosselin 1976). The lowest lethal oral dose reported for
humans is 30 mg/kg (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Material may burn but does not ignite readily (*DOT
1984).
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish fire using agent suitable for type of
surrounding fire; material itself does not burn or burns with difficulty.
Use water in flooding quantities as fog. Use alcohol foam, carbon dioxide,
or dry chemical (Student 1981, p. 482).
Special Fire Fighting Procedures: Not Found >
Unusual Fire and Explosion Hazards: When heated, emits highly toxic fumes
(*Sax 1979). Fire may produce irritating or poisonous gases. Runoff from
fire control or dilution water may cause pollution (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Osol 1980)
Conditions to Avoid: Protect from light (*Merck 1983)
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CAS Registry Number: 57-24-9
Page 3 of 3
STRYCHNINE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Material (and its salts) is used for destroying rodents and predatory
animals and for trapping fur-bearing animals (*Merck 1983).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53). Avoid breathing dusts, and fumes from
burning materials. Keep upwind. Avoid bodily contact with the material.
Do not handle broken packages without protective equipment. Wash away
any material which may have contacted the body with copious amounts
of water or soap and water (Student 1981, p. 482).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 57-24-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
STRYCHNINE
(57-24-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance. Characteristics:
Pure Forms - Colorless, transparent crystals or white crystalline powder.
Odor - None; bitter taste.
Commercial Form - Poisoned baits, usually as colored grain.
Uses - Rodenticide, sedatives, veterinary products.
Other Names - Certox, Kwik-Kil, Mouse-Rid, Mouse-Tox, Ro-Dex, Sanaseed,
Strychinos, strychnidin-10-one.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, sodium bicarbonate, pancuronium bromide or curare,
succinylcholine.
Signs and Symptoms of Acute Strychnine Exposure:
Warning: Strychnine may induce convulsions within 15 to 60 minutes following
exposure. Caution is advised.
Respiratory paralysis and arrest are likely to occur following severe exposure
to strychnine. Signs and symptoms of acute exposure generally involve
excitation of all portions of the central nervous system. Convulsions,
bilateral horizontal nystagmus (rapid, synchronous, horizontal oscillations of
the eyeballs), agitation, restlessness, apprehension, and abrupt, jerking
movements of the extremities may occur.
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CAS Registry Number: 57-24-9
Page 2 of 3
STRYCHNINE
Victims may also experience stiffness, painful muscle cramping (especially in
the legs), and opisthotonos (spasm in which the spine and extremities are bent
with convexity forward, the body resting on the head and heels). Vomiting and
renal failure, as well as cyanosis (blue tint to skin and mucous membranes)
and rhabdomyolysis (destruction of skeletal muscle), may be found.
Emergency Life-Support Procedures:
Acute exposure to strychnine may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to strychnine.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to strychnine.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!.
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CAS Registry Number: 57-24-9
Page 3 of 3
STRYCHNINE
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
6. Wash exposed skin areas THOROUGHLY with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!
3. DO NOT induce vomiting or attempt to neutralize.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administereing a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 57-47-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHYSOSTIGMINE
CAS Registry Number: 57-47-6
Synonyms: Calabarine; Carbamic Acid, Methyl-, Ester with Eseroline; Erserine;
Eserine; Eserolein, Methylcarbamate (Ester); Esromiotin; Ezerin; Physostol;
Pyrrolo(2,3-b)indol-5-ol, l,2,3,3a,8,8a-Hexahydro-l,3a,8-Trimethyl-,
Methylcarbamate (Ester), (3aS-cis)-
Chemical Formula: C15H21NSO2
Molecular Weight: 275.34
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (mus)
4.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 221-223°F, 105-106°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (*Merck 1976)
Appearance and Odor: White, odorless, microcrystalline powder (*Osol
1980)
-------
CAS Registry Number: 57-47-6
Page 2 of 4
PHYSOSTIGMINE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Gilman 1980)
Skin: Yes (*Gilman 1980)
Ingestion: Yes (*Gilman 1980)
Health Hazards (Acute, Delayed, and Chronic): Super toxic. Probable oral
lethal dose is less than 5 mg/kg for a 70 kg (150 Ib.) person (*Gosselin
1984). Material is a cholinesterase inhibitor. Effects of exposure may
involve the respiratory, gastrointestinal, cardiovascular and central
nervous systems. Death occurs due to respiratory paralysis or impaired
cardiac function. Time to death may vary from 5 minutes to 24 hours, in
severely poisoned patients, depending on factors such as the dose and route
(*Goodman 1980).
Medical Conditions Generally Aggravated by Exposure: Persons with asthma
and/or persons that require drugs containing choline esters are at risk
(*Osol 1975).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is a carbamate pesticide (Hayes 1982, p.
436). As for carbamate pesticides, extinguish fire using agent suitable
for type of surrounding fire (material itself burns with difficulty). Use
water in flooding quantities as fog. Use alcohol foam, carbon dioxide or
dry chemical (Student 1981, p. 104).
Special Fire Fighting Procedures: This is a carbamate pesticide (Hayes
1982, p. 436). As for carbamate pesticides, wear self-contained breathing
apparatus when fighting fires (Student 1981, p. 104).
Unusual Fire and Explosion Hazards: It is a slight fire hazard (Sax 1984,
p. 2228).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 57-47-6
Page 3 of 4
PHYSOSTIGMINE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Keep from light and heat (*Merck
1976).
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2228).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Physostigmine is a carbamate pesticide (Hayes 1982, p. 436). Material is
used as a cholinergic (anticholinesterase) agent and as a veterinary
medication (*Merck 1976). Listed as a carbamate pesticide in Sections III
and VII, however, physostigmine is not registered in the U.S. as such
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is a carbamate pesticide (Hayes 1982, p. 436). As for other carbamate
pesticides, avoid breathing dusts, and fumes from burning materials. Keep
upwind. Avoid bodily contact with the material. Wash away any material
which may have contacted the body with copious amounts of water or soap and
water (*Student 1981).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: General symptoms include: increased
secretions, fatigability and generalized weakness, involuntary twitching,
severe weakness of skeletal muscles. Symptoms of exposure to material by
major organ system: gastrointestinal: lack of appetite, nausea and
vomiting, abdominal cramps and diarrhea. Central nervous system:
confusion, uncoordination, slurred speech, loss of reflexes, rapid,
irregular breathing, generalized convulsions, and coma. Cardiovascular:
slowed heart beat resulting in hypotension and fall in cardiac output
(*Goodman 1980). .-
-------
CAS Registry Number: 57-47-6
Page 4 of 4
PHYSOSTIGMINE
SECTION IX (continued)
Emergency and First Aid Procedures: Administer artificial respiration and
oxygen if needed (Sax 1984, p. 2228). If the victim's skin and hair are
contaminated, bathe with soap and water. If the material was ingested, the
stomach must be emptied (*Morgan 1976).
-------
CAS Registry Number: 57-57-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPIOLACTONE, beta-
CAS Registry Number: 57-57-8
Synonyms: beta-Propiolactone; 2-Oxetanone; 3-Hydroxypropionic Acid Lactone;
3-Hydroxypropionic Acid, beta-Lactone; 3-Propanolide; 3-Propiolactone;
beta-Propionolactone; beta-Proprolactone; Betaprone; BPL; Hydracrylic Acid
Beta-Lactone; Hydracrylic Acid, beta Lactone; Propanoic Acid,
3-Hydroxy-,beta-Lactone; Propanolide; Propiolactone; Propionic Acid
3-Hydroxy-beta-Lactone; Propionic Acid, 3-Hydroxy-, beta-Lactone
Chemical Formula: CSH4O2
Molecular Weight: 72.06
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.074 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 324°F, 162°C, decomposes (*Merck 1976)
Specific Gravity (H2O=1): 1.146 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 3.4 at 25°C (*IARC 1972-1985)
Melting Point: -27°F, -33°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 37% by volume (*Merck 1976)
-------
CAS Registry Number: 57-57-8
Page 2 of 4
PROPIOLACTONE, beta-
SECTION II (continued)
Appearance and Odor: A colorless liquid with a slightly sweetish, pungent
odor (*Encyc Occupat Health and Safety 1971; *IARC 1972-1985)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 1.5 mg/ms, (0.5 ppm); STEL 3 mg/ms,(l ppm) (ACGIH, 19i
30)
IDLH: Not Found
Other Limits Recommended: Industrial substance suspect of carcinogenic
potential for humans (ACGIH 1984, p. 41).
Routes of Entry: Inhalation: Yes (*Sax 1968)
Skin: Yes (Weiss 1980, p. 776)
Ingestion: Yes (*Sax 1968)
Health Hazards (Acute, Delayed, and Chronic): The toxicity potential of
this material via inhalation or ingestion is high; may cause death or
permanent injury after very short exposures to small quantities (*Sax
1968). It is a carcinogen (Weiss 1980, p. 776).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 70°C (158°F) (no method given) (*Merck 1976)
Flammable Limits:
LEL: 2.9% (*NFPA 1979)
UEL: Not Found
Extinguishing Methods: Alcohol foam (*Sax 1979). Extinguish with water,
dry chemical, foam, or carbon dioxide (Weiss 1980, p. 776).
Special Fire Fighting Procedures: Wear air mask, goggles or face shield,
rubber gloves, and protective clothing to prevent all skin contact. Cool
exposed containers with water (Weiss 1980, p. 776).
Unusual Fire and Explosion Hazards: Containers may explode (Weiss 1980,
p. 776). When heated to decomposition, it emits acrid smoke and fumes (Sax
1984, p. 2102).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unftable:
Stable: Yes, stable when stored at 5°C (*Merck 1983)
-------
CAS Registry Number: 57-57-8
Page 3 of 4
PROPIOLACTONE, beta-
SECTION V (continued)
Conditions to Avoid: Avoid storing in areas of exposure to the direct
rays of the sun and in areas of high fire hazard (*Sax 1968). Tends to
polymerize on storage (*IARC 1972-1985).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2102).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Avoid elevated temperatures (Weiss 1980, p.
776).
SECTION VI -- USE INFORMATION
Intermediate in organic synthesis; disinfectant (*Merck 1976); sterilant
for blood plasma, tissue grafts, vaccines, enzymes and surgical instruments
(*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid contact with liquid. Keep people away. Stop discharge (Weiss 1980,
p. 776). Avoid inhalation (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Neoprene POOR/LIMITED
Nitrile POOR/LIMITED
PE POOR/MANY
PVC POOR/LIMITED
Viton POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 57-57-8
Page 4 of 4
PROPIOLACTONE, beta-
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation causes irritation of nose,
throat, and respiratory tract. Contact of liquid with eyes causes
irritation and tears. Contact with skin causes irritation and blistering;
fluid from blisters may cause additional blistering of adjacent skin.
Ingestion causes burns of mouth and stomach (Weiss 1980, p. 776).
Emergency and First Aid Procedures: Get medical attention following all
exposures to this compound. In case of inhalation, move victim to fresh
air; if breathing has stopped, give artificial respiration. If there has
been eye contact, flush eyes with water for at least 15 minutes. In case
of skin contact, flush with water (Weiss 1980, p. 776).
-------
CAS Registry Number: 57-64-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHYSOSTIGMINE, SALICYLATE (1:1)
CAS Registry Number: 57-64-7
Synonyms: (SANSS 1983 Synonyms): Eserine Salicylate; Physostol Salicylate;
Salicylic Acid, compound with Physostigmine; Benzoic Acid, 2-Hydroxy-, compound
with (3aS-cis)-l,2,3,3a,8,8a-Hexahydro-l,3a,8-
Trimethylpyrrolo[2,3-b]indol-5-yl Methylcarbamate (1:1)
Chemical Formula: C15H21NSO2-C7H6O3
Molecular Weight: 413.52
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 2.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 365-369°F, 185-187°C (Merck 1983, p. 1065)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 gram/75 mL at 25°C (Merck 1983, p. 1065)
Appearance and Odor: Crystal form that turns red on exposure to heat or
light (Merck 1983, p. 1065). ;
-------
CAS Registry Number: 57-64-7
Page 2 of 3
PHYSOSTIGMINE, SALICYLATE (1:1)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2228)
Health Hazards (Acute, Delayed, and Chronic): This compound is similar to
physostigmine. It is classified as super toxic. The probable oral lethal
dose (humans) is less than 5 mg/kg or a taste for a 150 Ib. person. It is
a cholinesterase inhibitor (Gosselin 1984, p. 11-245).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2228).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 57-64-7
Page 3 of 3
PHYSOSTIGMINE, SALICYLATE (1:1)
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This compound is similar to physostigmine
(Gosselin 1984, p. H-245). Symptoms include nausea, vomiting, abdominal
cramps, diarrhea, excessive salivation, sweating, lassitude, weakness,
tightness in chest, vision disorders, tearing, ciliary muscle spasm, loss
of muscle coordination, slurring of speech, twitching of muscle, difficulty
in breathing, bluing of skin, convulsions, coma and death (Gosselin 1984,
p. 111-89).
Emergency and First Aid Procedures: This compound is similar to
physostigmine (Gosselin 1984, p. 11-245). Give oxygen and artificial
respiration as needed. Wash contaminated areas of the skin with soap and
water. Irrigate the eyes with water or saline. Keep patient under
constant observation for at least 24 hours (Gosselin 1984, p. 111-89).
COMMENTS
Sources with no information:
Doull 1980
Clayton and Clayton 1981-82
NFPA 1984
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CAS Registry Number: 57-74-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLORDANE
CAS Registry Number: 57-74-9
Synonyms: l,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-Hexahydro-4,7-
Methanoindene; l,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-Hexahydro-4,7-Methylene
Indane; 4,7-Methano-lH-Indene, l,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-
Hexahydro-; 4,7-Methanoindan, 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-Tetrahydro-;
1068; Aspon-Chlordane; CD 68; Chlor Kil; Chlordane, Liquid (DOT); Chlorindan;
Corodan; Dowchlor; ENT 9,932; ENT-9932; HCS 3260; Kypchlor; M 140; M 410;
NCI-C00099; Niran; Octa-Klor; Octachloro-4,7-Methanohydroindane; Octachloro-
4,7-Methanotetrahydroindane; Octachlorodihydrodicyclopentadiene; Oktaterr;
Ortho-Klor; Synklor; TAT Chlor 4; Topiclor; Toxichlor; Velsicol 1068; Belt
Chemical Formula: C10H6C18
Molecular Weight: 409.80
SECTION I « REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(cat) 0.1 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II » PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 347°F, 175°C at 2 mmHg ('Sunshine 1969)
Specific Gravity (H2O=1): 1.56-1.57 at 25°C/0°C (*Merck 1983)
Vapor Pressure (mmHg): 0.00001 at 25°C (*Sunshine 1969)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 57-74-9
Page 2 of 4
CHLORDANE
SECTION II (continued)
Solubility in Water: Insoluble (*Merck 1983)
Appearance and Odor: Amber viscous liquid with an aromatic, slightly
pungent odor (*Merck 1983, *CHRIS 1978)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Air: TWA 0.5 mg/ms (skin) (NIOSH 1987)
ACGIH TLV: 0.5 mg/m3 (ACGIH 1986-87)
IDLH: 500 mg/ms (*Clayton and Clayton 1981-82)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Gosselin 1984, pp. III-108-109)
Skin: Yes — More toxic to humans than by oral
administration (Gosselin 1984, pp. III-108-109)
Ingestion: Yes (Gosselin 1984, pp. III-108-109)
Health Hazards (Acute, Delayed, and Chronic): Fatal oral dose to adult
humans is between 6 and 60 g with onset of symptoms within 45 minutes to
several hours after ingestion, although symptoms have occurred following
very small doses either orally or by skin exposure. Some reports of
delayed development of liver disease, blood disorders and upset stomach.
Chlordane is considered to be borderline between a moderately and highly
toxic substance (Gosselin 1984, pp. III-108-109).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Flammable/combustible (*DOT 1984)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, and foam. Large fires: water spray, fog, or foam. Move containers
from fire area if it can be done without risk. Cool containers that are
exposed to flames with water from the side until well after fire is out
(*DOT 1984).
Special Fire Fighting Procedures: Isolate hazard area and deny entry.
Stay upwind. Wear positive pressure breathing apparatus and special
protective clothing. Isolate for 1/2-mile in all directions if tank car or
truck is involved in the fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Flammable/combustible material; may
be ignited by heat, sparks or flames. Vapors may travel to a source of
ignition and flash back. Run-off to sewers may create fire or explosion
hazard. Containers may explode in heat of fire. Vapors are toxic indoors
-------
CAS Registry Number: 57-74-9
Page 3 of 4
CHLORDANE
SECTION IV (continued)
and outdoors (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Verschueren 1983, pp. 380-381)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Loses chlorine in presence of
alkaline reagents; should not be formulated with any solvent, carrier,
diluent or emulsifier which has alkaline reaction (*Merck 1983).
Hazardous Decomposition or Byproducts: Chlordane degrades under natural
environmental conditions to photoisomers, such as photo-cis- chlordane,
which are more toxic to certain animals than chlordane and also showed
higher bioaccumulation (*Khan et al. 1970).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
As of 1983, the only use in USA is for termite control (*IARC 1972-1985).
Previously used as agricultural home and garden pesticide or insecticide
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Shut off ignition sources.
Eliminate all smoking or flames in hazard area. Do not touch spilled
material. Use water spray to reduce vapors. Stay upwind. Small spills:
take up with sand or other noncombustible absorbent material, place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 57-74-9
Page 4 of 4
CHLORDANE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene GOOD/LIMITED**
Nitrile POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Increased sensitivity to stimuli,
tremors, muscular incoordination, and convulsions with or without coma
(Gosselin 1984, pp. 111-108-109).
Emergency and First Aid Procedures: Move victim to fresh air and give
artificial respiration if indicated. Remove and isolate contaminated
clothing and shoes at site. If exposure to skin or eyes, flush with
running water for at least 15 minutes. Try to keep victim quiet. Effects
may be delayed so keep victim under observation (*DOT 1984).
-------
CAS Registry Number: 58-36-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENOXARSINE, 10,10'-OXYDI-
CAS Registry Number: 58-36-6
Synonyms: (SANSS 1983 Synonyms) lOH-Phenoxarsine, 10,10'-oxybis;
Bis(Phenoxarsin-10-yl)Ether; Bis(lO-Phenoxarsinyl) Oxide; Bis(lO-Phenoxarsyl)
Oxide; Estabex ABF; OBPA; SA 546; DID 47
Chemical Formula: C24H16As2O3 (Merck 1983, p. 998)
Molecular Weight: 502.23 (Merck 1983, p. 998)
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 24 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 363-365°F, 184-185°C (Merck 1983, p. 998)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (5 ppm at 20°C) (Merck 1983,
p. 998)
Appearance and Odor: Colorless crystals (Merck 1983, p. 998)
-------
CAS Registry Number: 58-36-6
Page 2 of 4
PHENOXARSINE, 10,10'-OXYDI-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 0.010 mg/m3 (Arsenic and Compounds) (NIOSH 1984, p. 661)
ACGIH TLV: Air: TWA 0.2 mg (Arsenic)/m3 (ACGIH 1984, p. 10)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific - Arsenic Compounds)
(Sax 1984, p. 320)
Skin: Yes (Non-Specific -- Arsenic Compounds)
(Sax 1984, p. 320)
Ingestion: Yes (Non-Specific -- Arsenic Compounds)
(Sax 1984, p. 320)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Arsenic
Compounds) Arsenic compounds are acutely poisonous by ingestion.
Ingestion or inhalation may result in chronic poisoning. Arsenic compounds
are recognized carcinogens of the skin, lungs, and liver (Sax 1984, p.
320).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Arsenic Compound, Solid, n.o.s.)
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam. Move container from fire area if you
can do so without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific ~ Arsenic Compound,
Solid, n.o.s.) Stay upwind; keep out of low areas. Wear self-contained
(positive pressure if available) breathing apparatus and full protective
clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Arsenic Compounds)
When heated to decomposition, it emits highly toxic fumes of arsenic (Sax
1984, p. 320).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 58-36-6
Page 3 of 4
PHENOXARSINE, 10,10'-OXYDI-
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used primarily for fungicidal and bactericidal protection
of plastics (Merck 1983, p. 998).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Arsenic Compound, Solid, n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Do not touch spilled material; stop leak if you can do so without
risk. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Arsenic Compounds)
Ingestion causes nausea, vomiting, and diarrhea. In severe cases, there
may be bloody vomitus and stools and the victim may suffer collapse and
shock with weak, rapid pulse, cold sweats, coma, and death. Symptoms of
chronic poisoning may include loss of appetite, cramps, nausea,
constipation or diarrhea, jaundice, itching and pigmentation of the skin
(Sax 1984, p. 320).
-------
CAS Registry Number: 58-36-6
Page 4 of 4
PHENOXARSINE, 10,10'-OXYDI-
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific — Arsenic Compound,
Solid, n.o.s.) Move victim to fresh air; call emergency medical care.
Remove and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 58-89-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - LINDANE
CAS Registry Number: 58-89-9
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 1,000): Cyclohexane,
1,2,3,4,5,6-Hexachloro-, Gamma-Isomer; Aalindan; Aficide; Agrisol G-20;
Agrocide; Agrocide 2; Agrocide 7; Agrocide 6G; Agrocide III; Agrocide WP;
Agronexit; Ameisenatod; Ameisenmittel Merck; Aparasin; Aphtiria; Aplidal;
Arbitex; BBH; Ben-Hex; Bentox 10; Benzene Hexachloride-gamma-isomer;
gamma-Benzene Hexachloride; Bexol; BHC; gamma-BHC; Celanex; Chloresene;
Codechine; DBH; Detmol-Extrakt; Detox 25; Devoran; Dol Granule; Drill
Tox-Spezial Aglukon; Ent 7,796; Entomoxan; Exagama; Forlin; Gallogama; Gamacid;
Gamaphex; Gamene; Gammahexa; Gammahexane; Gammalin; Gammalin 20; Gammaterr;
Gammex; Gammexane; Gammopaz; Gexane; HCCH; HCH; gamma-HCH; Heclotox; Hexa;
Hexachloran; gamma-Hexachloran; Hexachlorane; gamma- Hexachlorane;
gamma-Hexachlorobenzene; l-alpha,2-alpha,3-beta,4-alpha,
5-alpha,6-beta-Hexachlorocyclohexane; gamma-Hexachlorocyclohexane; gamma-
1,2,3,4,5,6-Hexachlorocyclohexane; Hexachlorocyclohexane, gamma-Isomer;
1,2,3,4,5,6-Hexachlorocyclohexane, gamma-Isomer; Hexatox; Hexaverm; Hexicide;
Hexyclan; HGI; Hortex; Inexit; Isotox; Jacutin; Kokotine; Kwell; Lendine;
Lentox; Lidenal; Lindafor; Lindagam; Lindagrain; Lindagranox; gamma-Lindane;
Lindane (DOT); Lindapoudre; Lindatox; Lindosep; Lintox; Lorexane; Milbol 49;
Mszychol; NCI-C00204; NEO-Scabicidol; Nexen FB; Nexit; Nexit-Stark; Nexol-E;
Nicochloran; Novigam; Omnitox; Ovadziak; Owadzlak; Pedraczak; Pflanzol;
Quellada; Sang gamma; Silvanol; Spritz-Rapidin; Spruehpflanzol; Streunex; Tap
85; TRI-6; Viton
Chemical Formula: C6H6C16 (Weast 1979, p. C-262)
Molecular Weight: 290.83 (Weast 1979, p. C-262)
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (cat)
25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
-------
CAS Registry Number: 58-89-9
Page 2 of 4
LINDANE
SECTION II (continued)
Boiling Point: 614°F, 323.4°C (Weast 1979, p. C-262); Decomposes
(NIOSH/OSHA 1978, p. 120)
Specific Gravity (H2O=1): 1.9 (DASE 1980, p. 529)
Vapor Pressure (mmHg): 0.0000094 at 20°C (Merck 1983, p. 789)
Melting Point: 234.5°F, 112.5°C (Weast 1979, p. C-262)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. C-262)
Appearance and Odor: Colorless solid with a musty odor; pure material is
odorless (NIOSH/OSHA 1978, p. 120).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 0.5 mg/m3 (NIOSH/OSHA 1978, p. 120)
ACGIH TLV: TWA 0.5 mg/m3 (ACGIH 1986)
IDLH: 1,000 mg/m3 (NIOSH/OSHA 1978, p. 120)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Gosselin 1984, p. III-240)
Skin: Yes (Gosselin 1984, p. III-240)
Ingestion: Yes (Gosselin 1984, p. IH-240)
Health Hazards (Acute, Delayed, and Chronic): Lindane is a stimulant of
the nervous system, causing violent convulsions that are rapid in onset and
generally followed by death or recovery within 24 hours (Hayes 1982, p.218).
The probable human oral lethal dose is 50-500 mg/kg, or between 1 teaspoon
and 1 ounce for a 150-lb (70 kg) person (Gosselin 1984, p. 11-286).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray, or
foam for small fires. Use water spray, fog, or foam for large fires. Move
container from fire area if this can be done without risk. Use water to
-------
CAS Registry Number: 58-89-9
Page 3 of 4
LINDANE
SECTION IV (continued)
keep fire-exposed containers cool (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Isolate hazard area and deny entry.
Stay upwind and keep out of low areas. Ventilate closed spaces before
entering. Wear positive pressure breathing apparatus and special
protective clothing. Fight fire from maximum distance, dike fire control
water for later disposal (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, this
compound emits toxic fumes of chlorine, hydrochloric acid, and phosgene
(Sax 1984, p. 366).
NFPA Flammability Rating: 1 (solution); 0 (dry)
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Thermal decomposition products may
include chlorine, hydrochloric acid, and phosgene (Sax 1984, p. 366).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Pesticide (Hawley 1981, p. 617) and scabicide (Hayes 1982, p. 221).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Sweep or shovel material into a clean, dry
container. Carefully collect remainder (DASE 1980, p. 529; DOT 1984,
Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 58-89-9
Page 4 of 4
LINDANE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED**
Butyl/Neoprene POOR/LIMITED**
CPE POOR/LIMITED**
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Contact with eyes or skin may produce
irritation (DASE 1980, p. 529). Vomiting, faintness, tremor, restlessness,
muscle spasms, unsteady gait, and convulsions may occur as a result of
exposure. Elevated body temperature and pulmonary edema have been reported
in children. Coma, respiratory failure and death can result. Exposure to
vapors of this compound or its thermal decomposition products may lead to
headache, nausea, vomiting, and irritation of the eyes, nose, and throat
(Gosselin 1984, pp. IH-240, 241).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes,
speed in removing material from the skin is of extreme importance. Remove
and isolate contaminated clothing and shoes at the site. Keep victim quiet
and maintain normal body temperature. Effect may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 59-88-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENYLHYDRAZINE HYDROCHLORIDE
CAS Registry Number: 59-88-1
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 457): Hydrazine, Phenyl-,
Hydrochloride; Hydrazine, Phenyl-, Monohydrochloride; Phenylhydrazine
Monohydrochloride; Phenylhydrazinium Chloride
Chemical Formula: C6H8N2-HC1
Molecular Weight: 144.62
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rabbit) 25 mg/kg (*NIOSH/RTECS 1985).
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not pertinent; it decomposes (Weiss 1980, p. 744)
Specific Gravity (H2O=1): Greater than 1 at 20°C (Weiss 1980, p. 744)
Vapor Pressure (mmHg): Not Found
Melting Point: 469-475°F, 243-246°C (Merck 1983, p. 1051)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (Merck 1983, p. 1051)
Appearance and Odor: White to tan solid; weak aromatic odor (Weiss 1980,
p. 744).
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CAS Registry Number: 59-88-1
Page 2 of 3
PHENYLHYDRAZINE HYDROCHLORIDE
r
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Occupational exposure to hydrazines recommended
standard: ceiling 0.6 mg/ms/2 hours (Air) (Sax 1984, p. 2190).
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 744)
Skin: Yes (Weiss 1980, p. 744)
Ingestion: Yes (Weiss 1980, p. 744)
Health Hazards (Acute, Delayed, and Chronic): This material is poisonous
if swallowed or if fumes are inhaled. Dust is irritating to eyes, nose,
and throat. Phenylhydrazine is a chronic poison (Weiss 1980, p. 744).
Phenylhydrazine is an industrial substance suspect of carcinogenic
potential for humans (ACGIH 1983, p. 43).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV « FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Combustible (Weiss 1980, p. 744)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water, foam, dry chemical, or carbon dioxide
(Weiss 1980, p. 744).
Special Fire Fighting Procedures: Wear goggles and self-contained
breathing apparatus (Weiss 1980, p. 744).
Unusual Fire and Explosion Hazards: Toxic and irritating hydrogen
chloride and oxides of nitrogen may be produced in fire (Weiss 1980, p.
744).
NFPA Flammabiiity Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 744)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): May be corrosive to metals (Weiss
1980, p. 744).
-------
CAS Registry Number: 59-88-1
Page 3 of 3
PHENYLHYDRAZINE HYDROCHLORIDE
SECTION V (continued)
Hazardous Decomposition or Byproducts: Hydrogen chloride and oxides of
nitrogen (Weiss 1980, p. 744).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 744)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Hemolytic (Merck 1983, p. 1051).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid contact with solid and dust. Restrict access. Disperse and flush
(Weiss 1980, p. 744). (Non-Specific -- Phenylhy^drazine) Keep
unnecessary people away; isolate hazard area a*nd deny entry. Stay
upwind; keep out of low areas. Do not touch spilled material; stop leak if
you can do it without risk. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Ingestion or inhalation of fumes can
cause nausea, jaundice, anorexia, and blood clots. It may also cause
anemia and liver injury. Contact with eyes causes irritation. Contact
with skin causes irritation and dermatitis. Inhalation of dust can cause
coughing and difficult breathing (Weiss 1980, p. 744).
Emergency and First Aid Procedures: Move victim to fresh air. Remove
contaminated clothing and shoes. For ingestion, give a large amount of
water; induce vomiting. If eyes are exposed, flush with water for at least
15 minutes. If skin is exposed, flush with water (Weiss 1980, p. 744).
-------
CAS Registry Number: 60-34-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL HYDRAZINE
CAS Registry Number: 60-34-4
Synonyms: 1-Methylhydrazine; Hydrazine, Methyl-; Hydrazomethane; MMH;
Monomethylhydrazine; UN 1244
Chemical Formula: CH6N2
Molecular Weight: 46.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.105 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 190°F, 87.5°C (*Merck 1983)
Specific Gravity (H2O=1): 0.874 at 25°C (*Merck 1983)
Vapor Pressure (mmHg): 49.6 at 25°C (*Sunshine 1969)
Melting Point: -62.3°F, -52.4°C (*Merck 1983)
Vapor Density (AIR=1): 1.6 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible with water (*Merck 1983)
Appearance and Odor: It is a colorless liquid (*Sax 1979) with an odor
characteristic of short-chain, organic amines, or ammonia-like (*Merck
1983, *Clayton and Clayton 1981-82).
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CAS Registry Number: 60-34-4
Page 2 of 4
METHYL HYDRAZINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 0.35 mg/m3 (skin) (*NIOSH/RTECS 1985)
ACGIH TLV: Ceiling 0.35 mg/m3 (skin) (*ACGIH 1983)
IDLH: 5 ppm (*Encyc Occupat Safety and Health 1983)
Other Limits Recommended: Methyl hydrazine is a suspected human carcinogen
with a NIOSH recommended ceiling concentration of 0.08 mg/m3/2 hour (*ACGIH
1984 and *NIOSH 1985). SPEGL 0.24 ppm (60 minutes) (NRC 1985b, pp. 23-36).
Routes of Entry: Inhalation: Yes (*Clayton and Clayton 1981-82)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Clayton and Clayton 1981-82)
Health Hazards (Acute, Delayed, and Chronic): Methyl hydrazine vapors are
extremely toxic and the liquid is corrosive to skin. Methyl hydrazine is
the strongest convulsant and the most toxic of methyl-substituted hydrazine
derivatives (*Clayton and Clayton 1981-82). It is more toxic than
hydrazine (*NFPA 1978). At high doses, it is a strong central nervous
system poison that can lead to convulsions and death (*Encyc Occupat Health
and Safety 1971)
Medical Conditions Generally Aggravated by Exposure: Skin rash may be
aggravated by skin exposure (*Encyc Occupat Health and Safety 1971).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 70°C (OC) (*Merck 1983)
Flammable Limits:
LEL: 2.5% (Sax 1984, p. 1858)
UEL: 97% (Sax 1984, p. 1858)
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, and foam. For large fires, use water spray, fog, or foam.
Keep unnecessary people away and isolate the hazardous area. Stay upwind
and keep out of low-lying areas (DOT 1984, Guide 28). Fire exposed
containers should be kept cool with water. Use water spray to disperse
vapors and protect men attempting to stop a leak which has not ignited
(*NFPA 1978). Move container from fire area if it can be done without risk
(*DOT 1984).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special (full) protective clothing. No skin surface should
be exposed (*NFPA 1978). Isolate area for 1/2-mile in all directions if a
tank car or truck is involved in a fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Extremely flammable; ignites
spontaneously under almost all normal temperature conditions (*NFPA 1978).
Water used to extinguish a fire may cause pollution and should be diked for
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CAS Registry Number: 60-34-4
Page 3 of 4
METHYL HYDRAZINE
SECTION IV (continued)
later disposal (DOT 1984, Guide 28). Water may be ineffective in
extinguishing fires due to the chemical's low flash point. Because of the
wide flammability limits, low flash point, and reignition hazard, dry
chemicals, carbon dioxide, water spray, and foam may not be as effective as
water dilution of fire area. The vapor is heavier than air; thus it may
accumulate sufficiently to flash back (*NFPA 1978).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Heat or flame should be avoided because
chemical is extremely flammable and explosive (*Sax 1979).
Incompatibility (Materials to Avoid): Ignites spontaneously in air when
in contact with porous materials (e.g., earth, asbestos, wood, or cloth)
(*NFPA 1978). Also ignites spontaneously on contact with strong oxidizing
agents (e.g., fluorine, chlorine trifluoride, fuming nitric acid, and
nitrogen tetroxide) (*Merck 1983).
Hazardous Decomposition or Byproducts: Methylhydrazine fires produce
irritating nitrogen oxides (*NFPA 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Used as a chemical intermediate and solvent (*ACGIH 1980). Also used as a
component of rocket propellants (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In the case of a spill or leak, shut off ignition sources, and extinguish
or disallow flares, smoking, or flames in the hazard area. Do not touch
the spilled material, and stop leak if it can be done without risk. Use
water spray to reduce vapors. For small spills, take up the chemical with
sand or other noncombustible absorbent material and place it in containers
for later disposal. For large spills, dike far ahead for later disposal
(*DOT 1984).
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CAS Registry Number: 60-34-4
Page 4 of 4
METHYL HYDRAZINE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/MANY
CPE POOR/LIMITED
Chlorobutyl GOOD/LIMITED
PVC POOR/LIMITED
Teflon POOR/MANY
Viton GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 60-34-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHYL HYDRAZINE
(60-34-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless liquid.
Odor - Ammonialike.
Uses - Chemical intermediate, solvent, rocket propellant.
Materials to Avoid - Porous materials, acids, oxidizers.
Caution: Extremely flammable. Avoid sources of extreme heat or ignition
including sparks or fire. Methyl hydrazine may spontaneously self-ignite.
Other Names - Hydrazomethane, 1-methylhydrazine, MMH, monomethylhydrazine,
UN 1244.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, pyridoxine.
Signs and Symptoms of Acute Methyl Hydrazine Exposure:
Warning: Symptoms may be delayed from hours to days. Caution is advised.
Symptoms of acute exposure to methyl hydrazine may include facial numbness,
facial swelling, and increased salivation. Headache, twitching, seizure,
convulsions, and coma may also occur. Gastrointestinal signs and symptoms
include anorexia, nausea, and vomiting. Pulmonary edema and hypotension (low
blood pressure) are common.
-------
EFATG
CAS Registry Number: 60-34-4
Page 2 of 3
METHYL HYDRAZINE
Methyl hydrazine is toxic to the liver, ruptures red blood cells, and may
cause kidney damage. Contact with the skin, eyes, or mucous membranes may
result in severe irritation and permanent damage.
Emergency Life-Support Procedures:
Acute exposure to methyl hydrazine may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methyl hydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methyl hydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 60-34-4
Page 3 of 3
METHYL HYDRAZINE
Ingestion Exposure:
1. Evaluate vital signs including .pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 60-41-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- STRYCHNINE, SULFATE
CAS Registry Number: 60-41-3
Synonyms: (NIOSH/RTECS Synonyms 1983, Volume 3, p. 650) Strychnine, Sulfate
(2:1); Strychnine Sulfate; Strychnidin-10-one, Sulfate (2:1)
Chemical Formula: C21H22N2O2- 1/2 H2O4S
Molecular Weight: 383.49
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
5 mg/kg (*NIOSH/RTECS 1985).
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 392°F, 200°C with decomposition (Merck 1983, p. 1269)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g dissolves in 35 mL, 7 mL boiling water (Merck
1983, p. 1269)
Appearance and Odor: Colorless, odorless, very bitter crystals; white
crystalline powder (Merck 1983, p. 1269).
-------
CAS Registry Number: 60-41-3
Page 2 of 3
STRYCHNINE, SULFATE
•
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 1156)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2473)
Health Hazards (Acute, Delayed, and Chronic): Violent poison! (Merck
1983, p. 1269). Lowest published lethal dose orally in humans is 30 mg/kg
(Weiss 1980, p. 1156).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Strychnine and Salts) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do it
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Strychnine and Salts)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Wear self-contained (positive pressure if
available) breathing apparatus and full protective clothing (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of sulfur oxides and nitrogen oxides (Sax 1984, p.
2473).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Protect from light (Merck 1983, p. 1269).
Incompatibility (Materials to Avoid): Alkalies, alkali carbonates and
-------
CAS Registry Number: 60-41-3
Page 3 of 3
STRYCHNINE, SULFATE
SECTION V (continued)
bicarbonates, benzoates, dichromates, bromides, iodides, tannic and picric
acids, salicylates, borax, gold chloride and other alkaloid precipitants,
piperazine, potassium-mercuric iodide (Merck 1983, p. 1269).
Hazardous Decomposition or Byproducts: Emits very toxic fumes of sulfur
oxides and nitrogen oxides when heated to decomposition (Sax 1984, p.
2473).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Has been used as a tonic and stimulant in veterinary medicine (Merck 1983,
p. 1269). Registered as a rodenticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Strychnine and Salts) Do not touch spilled material;
stop leak if you can do it without risk. Small spills: take up with sand
or other noncombustible absorbent material and place into containers
for later disposal. Small dry spills: with clean shovel place material
into clean, dry container and cover; move containers from spill area.
Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 60-41-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
STRYCHNINE SULFATE
(60-41-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless crystals or white, crystalline powder.
Odor - None; bitter taste.
Uses - Rodenticide, tonic and stimulant in veterinary medicine.
Other Names - Kilmice; Mole-Nots; Mouse-Nots; strychnidin-10-one, sulfate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, sodium bicarbonate, pancuronium bromide or curare,
succinylcholine.
Signs and Symptoms of Acute Strychnine Sulfate Exposure:
Warning: Strychnine sulfate may induce convulsions within 15 to 60 minutes
following exposure. Caution is advised. Vital signs should be monitored
closely.
Signs and symptoms of acute exposure to strychnine sulfate generally involve
excitation of all portions of the central nervous system. Convulsions,
bilateral horizontal nystagmus (rapid, synchronous, horizontal oscillations of
the eyeballs), agitation, restlessness, apprehension, and abrupt, jerking
movements of the extremities may occur.
-------
EFATG
CAS Registry Number: 60-41-3
Page 2 of 3
STRYCHNINE SULFATE
Victims may also experience stiffness, painful muscle cramping (especially in
the legs), opisthotonos (spasm in which the spine and extremities are bent
with convexity forward, the body resting on the head and heels), and vomiting.
Respiratory paralysis and arrest are likely to occur following severe exposure
to strychnine sulfate. Cyanosis (blue tint to skin and mucous membranes),
rhabdomyolysis (destruction of skeletal muscle), and renal failure may also be
found.
Emergency Life-Support Procedures:
Acute exposure to strychnine sulfate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to strychnine sulfate.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to strychnine sulfate.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
-------
EFATG
CAS Registry Number: 60-41-3
Page 3 of 3
STRYCHNINE SULFATE
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. THOROUGHLY wash exposed skin areas with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
Warning: Any unnecessary sensory input may induce seizures. Isolate the
victims from any avoidable distractions.
2. RUSH to a health care facility!
3. DO NOT induce vomiting or attempt to neutralize.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 60-51-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIMETHOATE
CAS Registry Number: 60-51-5
Synonyms: 8014 Bis HC; Acetic Acid, O,O-DimethyldithiophosphoryI-, N-Mono-
methylamide Salt; American Cyanamid 12,880; BI 58; CL 12880; Cygon; Cygon 4E;
Cygon Insecticide; Daphene; De-Fend; Demos-L40; Dimethogen; Dimeton; Dimevur;
ENT 24650; Experimental Insecticide 12,880; FIP; Fosfotox; Fosfotox R; Fosfotox
R 35; Fostion MM; Lurgo; NCI-COO 135; O,O-Dimethyl S-(N-Methyl- carbamoylmethyl)
Dithiophosphate; O.O-Dimethyl S-(N-Methylcarbamoylmethyl) Phosphorodithioate;
O,O-Dimethyl S-Methylcarbamoylmethyl Phosphorodithioate;
O,O-Dimethyldithiophosphorylacetic Acid, N-Monomethylamide Salt; PEI 75;
Perfecthion; Perfekthion; Phosphamid; Phosphamide; Phosphorodithioic Acid
O,O-Dimethyl Ester, Ester With 2-Mercapto-N-Methylacetamide; Phosphor-
odithioic Acid, O,O-Dimethyl S-(2-(Methylamino)-2-Oxoethyl) Ester; Racusan;
Rogor; Rogor 20L; Rogor 40; Rogor L; Rogor P; Roxion; S-Methylcarbamoylmethyl
O,O-Dimethyl Phosphorodithioate; Sinoratox; Systoate
Chemical Formula: C5H12NO3PS2
Molecular Weight: 229.28
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDBO oral
(mammal) 15 mg/kg (*NIOSH/RTECS 1985).
TPQ: 500/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.277 at 65°C (*Merck 1983)
Vapor Pressure (mmHg): 0.0000085 at 77°F ('Worthing 1979)
Melting Point: 125°F, 52°C (*Merck-1983), 113-117°F, 45-47°C for
technical product (Worthing 1983) .
-------
CAS Registry Number: 60-51-5
Page 2 of 4
DIMETHOATE
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 2-3 g/100 ml (*Spencer 1982)
Appearance and Odor: A white crystalline solid (*Spencer 1982) with a
camphor-like odor (*Worthing 1979); white to greyish crystals for technical
product (Worthing 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: ADI 0.02 mg/kg (*Hayes 1975).
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and
Safety 1983)
Skin: Yes (*Encyc Occupat Health and Safety 1983)
Ingestion: Yes (*Encyc Occupat Health and
Safety 1983)
Health Hazards (Acute, Delayed, and Chronic): Very toxic; the probable
oral lethal dose in humans is between 50-500 mg/kg, or between 1 teaspoon
and 1 ounce for a 70 kg (150 Ib.) person. Dimethoate is a cholinesterase
inhibitor, meaning it affects the central nervous system. Death is due to
respiratory arrest arising from failure of respiratory center, paralysis of
respiratory muscles, intense bronchoconstriction or all three (*Gosselin
1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 124°F (CC) (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is an organophosphate insecticide
(*White-Stevens 1971; *Worthing 1979). Methods for organophosphorus
pesticides are as follows. Small fires: dry chemical, carbon dioxide,
water spray, and foam. Large fires: water spray, fog, or foam (DOT 1984,
Guide 55).
-------
CAS Registry Number: 60-51-5
Page 3 of 4
DIMETHOATE
SECTION IV (continued)
Special Fire Fighting Procedures: Procedures for organophosphorus
pesticides are as follows. Dike fire control water for later disposal, do
not scatter the material. Wear positive pressure breathing apparatus and
protective clothing. Fight fire from maximum distance (DOT 1984, Guide
55).
Unusual Fire and Explosion Hazards: As with other organophosphorus
pesticides, container may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1973)
Conditions to Avoid: The temperature of storage should not exceed
70-80°F. Keep away from sources of heat, flames, or spark-generating
equipment (*Farm Chemicals Handbook 1983). Unstable in alkaline
solution. Hydrolyzed by aqueous alkali. Stable in aqueous solutions.
The compound is stable for 2 years under environmental conditions if
stored in undamaged, original containers (*Spencer 1973).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Dimethoate is a contact and systemic organophosphate insecticide effective
against a broad range of insects and mites when applied on a wide range of
crops (* Worthing 1979; *SRI; * White-Stevens 1971). It has not been
produced in the U.S. since 1982 (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Dimethoate is an organophosphate insecticide (*White-Stevens 1971;
* Worthing 1979). Precautions for organophosphorus pesticides
include the following. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
-------
CAS Registry Number: 60-51-5
Page 4 of 4
DIMETHOATE
SECTION VII (continued)
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 60-51-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIMETHOATE
(60-51-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystalline solid.
Odor - Camphorlike (familiar, fragrant, penetrating).
Commercial Form - White to greyish crystals.
Use - Systemic insecticide-acaricide.
Material to Avoid - Alkali.
Other Names - American Cyanamid 12,880; Cygon; Daphene; Dimet, Dimethogen,
O,O-dimethyl S-methylcarbamoylmethyl phosphorodithioate; Dimeton, Dimevur,
FIP, Fosfotox, Fostion MM, Lurgo, Perfekthion, Phosphamide, Racusan, Rogor,
Roxion, Sinoratox, Systoate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, atropine,
pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Dimethoate Exposure:
Note: Dimethoate is a cholinesterase inhibitor.
Acute exposure to dimethoate may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
-------
EFATG
CAS Registry Number: 60-51-5
Page 2 of 3
DIMETHOATE
The heart rate may decrease following oral exposure or increase following
dermal exposure. Hypotension (low blood pressure) and chest pain may be noted.
Hypertension (high blood pressure) is not uncommon. Respiratory effects may
include dyspnea (shortness of breath), respiratory depression, and respiratory
paralysis. Psychosis may occur.
Emergency Life-Support Procedures:
Acute exposure to dimethoate may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dimethoate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dimethoate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
-------
EFATG
CAS Registry Number: 60-51-5
Page 3 of 3
DIMETHOATE
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Activated charcoal may be administered if victims are conscious and
alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4
to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
4. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
5. Transport to a health care facility.
-------
CAS Registry Number: 62-38-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENYLMERCURY ACETATE
CAS Registry Number: 62-38-4
Synonyms: (Acetoxymercuri)Benzene; Acetic Acid, Phenylmercury Deriv;
Acetoxyphenylmercury; Agrosan GN 5; Algimycin; Antimucin WDR; Bufen; Ceresan
Universal; Contra Creme; Dyanacide; Femma; FMA; Fungitox OR; Gallotox; HL-331;
Hostaquick; Kwiksan; Leytosan; Liquiphene; Mercury(II) Acetate, Phenyl-;
Mercury, (Acetato)Phenyl-; Mersolite; Mersolite 8; Metasol 30; Norforms;
Phenmad; Phenomercuric Acetate; Phenylmercuriacetate; Phenylmercuric Acetate;
Phix; PMA; PMAC; PMacetate; PMAL; PMAS; Programing Purasan-SC-10; Puraturf 10;
Quicksan 20; Sanitized SPG; SC-110; Shimmerex; Spor-Kil; TAG; Trigosan;
Ziarnik; Mercury,(Acetato-O)Phenyl-
Chemical Formula: C8H8HgO2
Molecular Weight: 336.75
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
22 mg/kg (*NIOSH/RTECS 1985).
TPQ: 500/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.000009 at 35°C (*Worthing 1979)
Melting Point: 300°F, 149°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 62-38-4
Page 2 of 4
PHENYLMERCURY ACETATE
SECTION II (continued)
Solubility in Water: 1 g/180 ml (*Osol 1980); soluble in about 600 parts
water (Merck 1983, p. 1052)
Appearance and Odor: White to creamy white crystalline powder or small
white prisms or leaflets. Odorless (*Osol 1980).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/m3 (skin) (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (*Hawley 1977)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic. The
probable oral lethal dose for humans is 5-50 mg/kg, between 7 drops and 1
teaspoonful for a 70 kg (150 Ib.) person (Gosselin 1984, p. 11-137).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Above 100°F (OC) (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, foam, or carbon dioxide on
solution. Use water as necessary, but run-off should be limited and
controlled to prevent it from entering streams or water supplies (*NFPA
1978).
Special Fire Fighting Procedures: Materials are extremely hazardous to
health, but areas may be entered with extreme care. Full protective
clothing, including self-contained breathing apparatus, rubber gloves,
boots and bands around legs, arms, and waist should be provided. No skin
should be exposed (*NFPA 1978).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases (*DOT 1984).
NFPA Flammability Rating: 1 (powder); 2 (solution)
-------
CAS Registry Number: 62-38-4
Page 3 of 4
PHENYLMERCURY ACETATE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Phenylmercuric ion is incompatible
with halides, with which precipitates are formed (*Osol 1980).
Hazardous Decomposition or Byproducts: When heated to decomposition, very
toxic mercuric fumes may be given off (Sax 1984, p. 100).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used as an antiseptic, fungicide, herbicide; mildewcide for paints;
slimicide in paper mills (*Hawley 1977). It was also used in contraceptive
gels and foams (*Osol 1980).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do it without
risk. Use water spray to reduce vapors. Small spills: take up
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (*DOT
1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms arising from acute exposure may
occur at varying intervals up to several weeks following exposure.
Ingestion of mercurial fungicide treated grain resulted in gastro-intestinal
irritation with nausea, vomiting, abdominal pain, and diarrhea.
Alkylmercurials produce severe neurologic toxicity, such as loss of feeling
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CAS Registry Number: 62-38-4
Page 4 of 4
PHENYLMERCURY ACETATE
in lips, tongue, and extremities, confusion, hallucinations, irritability,
sleep disturbances, staggering walk, memory loss, slurred speech, auditory
defects, emotional instability, and inability to concentrate. It is also a
strong skin irritant; erythema and blistering may result 6-12 hours after
exposure (*Rumack 1975 to Present). Phenylmercury acetate, at sufficient
concentration, is expected to be injurious to the eye externally (*Grant
1974).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin and eyes with running water for at least 15 minute
Speed in removing material from the skin is of extreme importance. Remo'
and isolate contaminated clothing and shoes at the site. Keep victim quiet
and maintain normal body temperature. Effects may be delayed; keep vict
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 62-53-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ANILINE
CAS Registry Number: 62-53-3
Synonyms: Aminobenzene; Aminophen; Aniline Oil; Anyvim; Benzenamine; Benzene,
Amino-; Benzidam; Blue Oil; CI 76000; CI Oxidation Base 1; Cyanol; Krystallin;
Kyanol; NCI-C03736; Phenylamine
Chemical Formula: C6H7N
Molecular Weight: 93.12
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 5,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 363-367°F, 184-186°C (*Merck 1976)
Specific Gravity (H2O=1): 1.022 at 20°C/20°C (*Merck 1976)
Vapor Pressure (mmHg): 0.67 at 25°C (*IARC 1972-85)
Melting Point: 21°F, -6.3°C (*Weast 1979)
Vapor Density (AIR=1): 3.22 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 gram in 28.6 mL water (*Merck 1976)
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CAS Registry Number: 62-53-3
Page 2 of 4
ANILINE
SECTION II (continued)
Appearance and Odor: Brown oily liquid (*Student 1981) with an aromatic
amine-like odor ("CHRIS 1978); colorless when freshly distilled (Merck
1983, p. 96)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Air: TWA 5 ppm (19 mg/ms) (skin) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 2 ppm (10 mg/ms) (skin); STEL 5 ppm (20 mg/ms) (skin)
("ACGIH 1982)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 46)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Merck 1976)
Skin: Yes (*Merck 1976)
Ingestion: Yes (*Merck 1976)
Health Hazards (Acute, Delayed, and Chronic): It is classified as very
toxic. Probable oral lethal dose in humans is 50-500 mg/kg for a 150 Ib.
person. Aniline poisoning is characterized by methemoglobin formation in
the blood and resulting cyanosis or blue skin (*Gosselin 1976). The
formation of methemoglobin interferes with the oxygen-carrying capacity of
the blood (Doull 1980, p. 319). The approximate minimum lethal dose for a
150 Ib. human is 10 grams (*Arena 1979). Serious poisoning may result from
ingestion of 0.25 mL (*Merck 1976).
Medical Conditions Generally Aggravated by Exposure: People at special
, risk-include individuals with glucose-6-phosphate-dehydrogenase deficiency
(*Arena 1979) and those with liver and kidney disorders, blood diseases, or
a history of alcoholism ("General Electric Co. 1978, MSDS #407).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 158°F, 70°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 1.3% (*NFPA 1978)
UEL: 20-25% (*Sax 1975)
Extinguishing Methods: Use water spray, dry chemical, foam or carbon
dioxide. Use water to keep fire-exposed containers cool (*NFPA 1984).
Special Fire Fighting Procedures: Fight fire from maximum distance. Dike
fire control water for later disposal and do not scatter material (*DOT
1984). If a leak or spill has not ignited, use water spray to control
vapors (*NFPA 1978). Wear self-contained breathing apparatus with a full
face piece operated in pressure-demand or other positive pressure mode
("NIOSH/OSHA 1981) and special protective clothing ("DOT 1984).
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CAS Registry Number: 62-53-3
Page 3 of 4
ANILINE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Combustion can produce toxic fumes
including nitrogen oxides and carbon monoxide (*General Electric Co. 1978,
MSDS #407). Aniline vapor forms explosive mixtures with air (*ITI 1982).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Heating (*Sax 1975)
Incompatibility (Materials to Avoid): It is incompatible with strong
oxidizers and strong acids (NIOSH/OSHA 1978, p. 46) and a number of other
materials (*Bretherick 1979; *ITI 1982; *Sax 1984).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes (*Sax 1975). These fumes may include nitrogen
oxides and carbon monoxide (General Electric Co. 1978, MSDS #407).
Hazardous Polymerization: May Occur: Yes (*IARC 1972-85)
May Not Occur:
Conditions to Avoid: Polymerizes to a resinous mass (*IARC 1972-85).
SECTION VI - USE INFORMATION
Manufacture of dyes, resins, varnishes, perfumes, shoe blacks, vulcanizing
rubber; solvent (*Merck 1976); inks, paint removers (*Dreisbach 1977);
herbicides, fungicides, explosives, photographic chemicals (*Hawley 1977);
isocyanates (*SRI); and rigid polyurethanes (*NIOSH/OSHA 1981). It is a
chemical intermediate for dyes and pigments and a number of other materials
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Shut off ignition sources; no flares, smoking or flames in
hazard area. Do not touch spilled material; stop leak if you can do it
without risk. Use water spray to reduce vapors. Small spills: take up
with sand or other non-combustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (*DOT 1984).
-------
CAS Registry Number: 62-53-3
Page 4 of 4
ANILINE
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl EXCELLENT/MANY
Butyl/Neoprene GOOD/LIMITED
CPE GOOD/LIMITED*
Neoprene POOR/MANY
Nitrile POOR/LIMITED
PE POOR/MANY
PVC POOR/MANY
Saranex GOOD/LIMITED
Teflon GOOD/LIMITED
Viton POOR/MANY
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 62-53-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
ANILINE
(62-53-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless, oily liquid, or solid below -6 degrees C (21 degrees
F).
Odor - Aromatic, aminelike.
Commercial Form - Brown, oily liquid.
Uses - Manufacture of resins, rigid polyurethane, varnish, perfume, ink, paint
remover, shoe blacks, artificial sweeteners, pesticides, Pharmaceuticals,
photographic chemicals, and optical whitening agents; solvent; analytical
reagent.
Other Names - Aminobenzene, Aminophen, Anyvim, Benzidam, Cyanol, Krystallin,
Kyanol, phenylamine.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, diazepam, phenytoin, dopamine,
levarterenol, methylene blue.
Signs and Symptoms of Acute Aniline Exposure:
Signs and symptoms of acute exposure to aniline may be severe and include
dyspnea (shortness of breath), respiratory paralysis, cardiac arrhythmias, and
cardiovascular collapse. Victims may experience headache, irritability,
disorientation, lethargy, weakness, incoordination, dizziness, and drowsiness.
Delerium, shock, convulsions, and coma may also be observed.
Gastrointestinal effects include dryness of throat, nausea, and vomiting.
Painful urination, oliguria (scanty urination), and hematuria (bloody urine)
may occur. Aniline may irritate the skin, eyes, and mucous membranes; cyanosis
(blue tint to skin and mucous membranes) is a common finding.
-------
EFATG
CAS Registry Number: 62-53-3
Page 2 of 3 v -
ANILINE
Emergency Life-Support Procedures:
Note: Victims at special risk include individuals with glucose-6-phosphate-
dehydrogenase deficiency, those with liver and kidney disorders, blood
diseases, or a history of alcoholism.
Acute exposure to aniline may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to aniline.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to aniline.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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EFATG
CAS Registry Number: 62-53-3
Page 3 of 3
ANILINE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of aniline is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of aniline may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 62-73-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DICHLORVOS
CAS Registry Number: 62-73-7
Synonyms: O,O-Dimethyl O-2,2-Dichlorovinyl Phosphate; 2,2-Dichloroethenyl
Phosphoric Acid Dimethyl Ester; 2,2-Dichlorovinyl Dimethyl Phosphate; Atgard;
Bay-19149; Bibesol; Brevinyl; Brevinyl E50; Canogard; Cekusan; Chlorvinphos;
Cyanophos; DDVF; DDVP; DEDEVAP; Deriban; Derribante; Dichlorman; Dichlorovas;
Dichlorovos; Dichlorphos; Dimethyl 2,2-Dichloroethenyl Phosphate; Dimethyl
2,2-Dichlorovinyl Phosphate; Divipan; ENT 20738; Equigard; Equigel; Estrosel;
Ethenol, 2,2-Dichloro-, Dimethyl Phosphate; Fecama; Herkal; Herkol; Krecalvin;
Mafu; Marvex; NCI-COO 113; Nerkol; No-Pest Strip; Nogos; Nuva; O,O-Dimethyl
Dichlorovinyl Phosphate; OMS 14; Phosphoric Acid, 2,2-Dichlorovinyl Dimethyl
Ester; Phosphoric Acid, 2,2-Dichloroethenyl Dimethyl Ester; Phosvit;
Szklarniak; Task; Vapona; Vaponite; 2,2-Dichloroethenyl phosphate; Atgard V;
Brevinyl Weedat 0002; Celcusan; Dichlorophos; Dimethyl dichlorovinyl phosphate;
Nuvan 100 EC; Unifos; Vapona insecticide; Astrobot; Estrosol; Nuvan; SD1750;
Fly fighter; Fly-die; Mopari UN NA 2783; Nogos 50; Nogos G; NSC-6738; OKO; Tap
9vp; Task Tabs; Tenac; UDVF; Unifos 50 EC; Vapona II; Verdican; Verdipor; Vinyl
alcohol, 2,2-Dichloro-, Dimethyl Phosphate; Vinylophos
Chemical Formula: C4H7C12O4P
Molecular Weight: 220.98
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.013 mg/liter/4 hours (*NIOSH/RTECS 1985).
TPQ: 1,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 284°F, 140°C at 20 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.415 at 25°C/4°C (*Merck 1976)
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CAS Registry Number: 62-73-7
Page 2 of 4
DICHLORVOS
SECTION I (continued)
Vapor Pressure (mmHg): 0.01 at 30°C (*Sunshine 1969)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Approximately 1 g/100 ml (*Merck 1976)
Appearance and Odor: Oily colorless to amber liquid with an aromatic
chemical odor (*Patty 1963; *NIOSH/OSHA 1981)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 mg/ms (skin) (NIOSH/OSHA 1978, p. 84)
ACGIH TLV: TWA 0.1 ppm, 1 mg/ms; STEL 0.3 ppm, 3 mg/ms (*AGGIH 1
IDLH: 200 mg/ms (NIOSH/OSHA 1978, p. 84)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): Dichlorvos is a very tox
compound with a probable lethal oral dose in humans between 50 and 50
mg/kg, or between 1 teaspoonful and 1 oz. for a 70 kg (150 Ib.) person.
However, brief exposure (30-60 minutes) to vapor concentrations as high
6.9 mg/liter did not result in clinical signs or depressed serum
cholinesterase levels. Toxic changes are typical of organophosphate
insecticide poisoning with progression to respiratory distress, respirator?
paralysis, and death if there is no clinical intervention (Gosselin 1984,
pp. 11-291 and III-336, 337).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Greater than 175°F (no method given) (*>
1978)
Flammable Limits: Moderately flammable (NIOSH/OSHA 1978, p. 84:
ignite easily (*DOT 1984)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Water in flooding quantities as fog, alcohol
dry chemical, or carbon dioxide (NIOSH/OSHA 1978, p. 84). Do not
the material (*DOT 1984).
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CAS Registry Number: 62-73-7
Page 3 of 4
DICHLORVOS
SECTION IV (continued)
Special Fire Fighting Procedures: Use self-contained breathing apparatus
with a full face piece operated on pressure-demand or other positive
pressure mode. Prevent skin contact with protective clothing (*NIOSH/OSHA
1978). Isolate area and deny entry. Fight fire from maximum distance.
Dike fire control water for future disposal (*DOT 1984).
Unusual Fire and Explosion Hazards: Highly toxic chloride fumes or
phosgene may be released when this product burns. Firefighters should take
precautions noted above (*Sax 1979).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Encyc Occupat Health and Safety 1971)
Stable:
Conditions to Avoid: Hydrolyzes in water (*Sunshine 1969).
Incompatibility (Materials to Avoid): Corrosive to iron and mild steel
(*Worthing 1979); acids or acid fumes (*Sax 1979).
Hazardous Decomposition or Byproducts: Toxic chloride fumes and phosgene
formed if heated to decomposition or on contact with acid or acid fumes
(*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Agricultural insecticide for use on crops, stored products, animals, and
premises; insecticide for slow release on pest-strips for pest control in
homes and aircraft; anthelmintic for dogs, swine, and horses; botacide for
horses; flea collars for dogs (*Gosselin 1976; *Rossoff 1974; *Worthing
1979; *SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Prevent access to area from public by isolating area and denying entry.
Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material;
stop leaks if you can do it without risk. Reduce vapors with water spray.
Take up small spills with sand or other noncombustible absorbent material
for later disposal in cannisters. Dike large spills far ahead of spill for
later disposal (*DOT 1984).
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CAS Registry Number: 62-73-7
Page 4 of 4
DICHLORVOS
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Sweating, twitching, contracted pupils,
respiratory distress (tightness in the chest and wheezing), salivation
(drooling), lacrimation (tearing), nausea, vomiting, abdominal cramps,
diarrhea, involuntary defecation and urination, slurred speech, coma, apnea
(cessation of breathing), and death (Doull 1980, pp. 367-368).
Emergency and First Aid Procedures: Call emergency medical care. If
victim was exposed by inhalation, move to fresh air. If not breathing,
give artificial respiration; if breathing is difficult, give oxygen. If
exposure was by contact, flush skin or eyes with running water for at least
15 minutes; it is critical to remove the material from the skin as quickly
as possible. Also remove contaminated clothing and shoes. Victim should
be kept quiet, warm, and observed for delayed effects (*DOT 1984).
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CAS Registry Number: 62-74-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SODIUM FLUOROACETATE
CAS Registry Number: 62-74-8
Synonyms: Acetic Acid, Fluoro-, Sodium Salt; 1080; Compd 1080; Compound No.
1080; Fluoroacetic Acid, Sodium Salt; Fratol; Furatol; Ratbane 1080; SMFA;
Sodium Fluoacetate; Sodium Fluoacetic Acid; Sodium Fluoracetate; Sodium
Monofluoroacetate; Ten-Eighty; TL 869; Yasoknock
Chemical Formula: C2H2FO2Na
Molecular Weight: 100.02
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.1 mg/liter/10 minutes (*NIOSH/RTECS 1985).
TPQ: 10/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.0 at 20°C (*ACGIH 1980)
Melting Point: 392°F, 200°C (*Weast 1979); decomposes at 392°F, 200°C
(*Hawley 1981)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate** 1): Not Found
Solubility in Water: 1110 g/liter at 25°C (*Weast 1979)
Appearance and Odor: White powder (*Weast 1979); odorless (*Hawley 1981).
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CAS Registry Number: 62-74-8
Page 2 of 3
SODIUM FLUOROACETATE
SECTION II (continued)
Usually marketed as water solution containing 0.5 percent Nigrosine as
black warning color (*Spencer 1982).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.05 mg/m3 (skin) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.05 mg/m3 (skin); STEL 0.15 mg/m3 (skin) (*ACGIH 1983)
IDLH: 5 mg/m3 (NIOSH/OSHA 1978, p. 166)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is super
toxic. The probable oral lethal dose in humans is less than 5 rag/kg, or a
taste (less than 7 drops) for a 150-lb. person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not combustible (NIOSH/OSHA 1978, p. 166)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray, or
foam. For large fires, use water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear self-contained, positive pressure breathing apparatus and full
protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards*' When heated to decomposition, it
emits highly toxic fumes of sodium oxide and fluorides (*Sax 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NIOSH/OSHA 1978)
*
Conditions to Avoid: Decomposing heat (*Sax 1984)
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CAS Registry Number: 62-74-8
Page 3 of 3
SODIUM FLUOROACETATE
SECTION V (continued)
Incompatibility (Materials to Avoid): None hazardous (NIOSH/OSHA 1978,
p. 166)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits fumes of sodium oxide and fluorides (*Sax 1984).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used for control of predatory animals, coyotes, and
rodents (*Farm Chemicals Handbook 1984).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Stay upwind; keep out of low areas
(*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting,
diarrhea, hyperactive behavior, convulsions, coma, and ventricular
fibrillation. Symptoms are usually seen within one-half hour of exposure,
but severe effects may be delayed as long as 20 hours (*Rumack 1975 to
Present).
Emergency and First Aid Procedures: There is no known specific treatment
for fluoroacetate exposure, but generally symptomatic support should be
provided (*Rumack 1975 to Present). Move victim to fresh air. Call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes (*DOT 1984).
-------
CAS Registry Number: 62-75-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NITROSODIMETHYLAMINE
CAS Registry Number: 62-75-9
Synonyms: N-Nitrosodimethylamine; Dimethyl Nitrosamine; Dimethylamine,
N-Nitroso-; Dimethylnitrosamine; Dimethylnitrosoamine; DMN; DMNA; Methanamine,
N-Methyl-N-Nitroso-; N,N-Dimethylnitrosamine; N-Methyl-N-Nitrosomethanamine;
N-Nitroso-N,N-Dimethylamine; NDMA
Chemical Formula: C2H6N2O
Molecular Weight: 74.08
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.173 mg/liter/4 hours (*NIOSH/RTECS 1985).
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 304-307°F, 151-153°C (*Merck 1983)
Specific Gravity (H20=l): 1.0048 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR-1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (*Merck 1983)
Appearance and Odor: Yellow oily liquid (*IARC 1972-1985); faint
characteristic odor (*Clayton and Clayton 1982)
-------
CAS Registry Number: 62-75-9
Page 2 of 4
NITROSODIMETHYLAMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA and STEL: Industrial substance suspected of carcinogenic
potential in humans (*ACGIH 1984)
IDLH: Not Found
Other Limits Recommended: Exposures should be avoided, in so far as
possible, or otherwise be kept to an absolute minimum; suspected of
carcinogenic potential in humans (*ACGIH 1984).
Routes of Entry: Inhalation: Yes ('Sunshine 1969)
Skin: Yes (*Sunshine 1969)
Ingestion: Yes (*Sunshine 1969)
Health Hazards (Acute, Delayed, and Chronic): Extremely high toxicity
(*Sunshine 1969). It is a suspected human carcinogen. The lowest lethal
oral dose in humans has been reported at 10 mg/kg/80 week intermittent
exposure (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Clayton and Clayton 1981, p. 3119)
Conditions to Avoid: Exposure to ultraviolet light (Clayton and
Clayton 1981, p. 3119).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, pp. 1180-1181).
-------
CAS Registry Number: 62-75-9
Page 3 of 4
NITROSODIMETHYLAMINE
•
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Nitrosodimethylamine was formerly used in the production of rocket fuels.
Presently used as an antioxidant, as an additive for lubricants and as a
softener of copolymers (Merck 1983, p. 952). It is an intermediate for
1,1-dimethylhydrazine (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). Spills can be
absorbed by celite or commercial spill absorbent. After absorbent
containing major share of nitrosamine has been picked-up (avoid dusts; do
not sweep), surface should be thoroughly cleaned with strong detergent
solution. If major spill occurs outside of ventilated area, room should be
evacuated and cleanup operation should be carried out by persons equipped
with self-contained breathing apparatus (*NRC 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting and
malaise (*Cooper 1980). Chronic exposure may cause liver disease with
jaundice and swelling (*Hamilton 1984) with low platelet count ("Cooper
1980).
Emergency and First Aid Procedures: Establish respiration; prevent
absorption; decontaminate with soap and water; for eye exposure, flush with
water (*Rumack 1975 to Present). (Poisonous Liquid or Gas, n.o.s.) Move
-------
CAS Registry Number: 62-75-9
Page 4 of 4
NITROSODIMETHYLAMINE
SECTION IX (continued)
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Remove
and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water '*
for at least 15 minutes. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 15).
-------
CAS Registry Number: 64-00-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHENOL, 3-(l-METHYLETHYL)-, METHYLCARBAMATE
CAS Registry Number: 64-00-6
Synonyms (NIOSH/RTECS, 1983, Volume I, p. 832): Carbamic Acid, Methyl-,
m-Cumenyl Ester; Carbamic Acid, N-Methyl-, 3-Isopropylphenyl Ester; Compound
10854; m-Cumenol Methylcarbamate; m-Cumenyl Methylcarbamate; ENT 25,500; ENT
25,543; H 5727; H 8757; HER. 5727; Hercules 5727; Hercules AC 5727; HIP;
m-Isopropylphenol N-Methylcarbamate; m-Isopropylphenyl Methylcarbamate;
m-Isopropylphenyl N-Methylcarbamate; 3-Isopropylphenyl Methylcarbamate;
N-Methyl m-Isopropylphenyl Carbamate; N-Methyl 3-Isopropylphenyl Carbamatc; QMS
162; 1PC; Phenol, m-Isopropyl-, Methylcarbamate; UC 10854; Union Carbide 10854;
Union Carbide UC-10,854
Chemical Formula: CUH16NO2
Molecular Weight: 193.27
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 10 mg/kg (*NIOSH/RTECS 1985).
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O»1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 162-165°F, 72-74°C (Hayes 1982, p. 450)
Vapor Density (AIR-1): Not Found
Evaporation Rate (Butyl acetate-1): Not Found
-------
CAS Registry Number: 64-00-6
. „ Page 2 of 4
PHENOL, 3-(l-METHYLETHYL)-, METHYLCARBAMATE
SECTION II (continued)
Solubility in Water: 85 ppm at 30°C (Hayes 1982, p. 450)
Appearance and Odor: Pure white solid without appreciable odor (Hayes
1982, p. 450).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) (DOT 1984, Guide 55)
Skin: Yes (Sax 1984, p. 820)
Ingestion: Yes (Sax 1984, p. 820)
Health Hazards (Acute, Delayed, and Chronic): It is a cholinesterase
inhibitor (Hayes 1982, p. 450).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamate Pesticide, Solid,
n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Wear positive pressure breathing apparatus and special
protective clothing. Move container from fire area if you can do it
without risk. Dike fire control water for later disposal; do not scatter
the material. Fight fire from maximum distance (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Container may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 64-00-6
Page 3 of 4
PHENOL, 3-(l-METHYLETHYL)-, METHYLCARBAMATE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Hayes 1982, p. 450)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 820)
Incompatibility (Materials to Avoid): Incompatible with alkalis (Hayes
1982, p. 450).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 820).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as an insecticide to protect cotton, fruit, vegetables and field
crops (Farm Chemicals Handbook 1984, p. C-236). Not registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Carbamate Pesticide, Solid, n.o.s.) Keep unnecessary
people away and stay upwind. Do not touch the material or handle broken
packages without protective clothing. Use water spray to reduce vapors.
Take up spills with non-combustible absorbent material. For small dry
spills, place material in a clean dry container with a clean shovel and
cover; remove from site of spill. For large spills dike far ahead
for later disposal (DOT 1984, Guide 55; Student 1981, p. 104).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may result in weakness,
dizziness, tightness in the chest, headache, pinpoint pupils, profuse
sweating, blurred vision, stomach pain, vomiting, skin rashes, and
giddiness (Hayes 1982, p. 451).
-------
CAS Registry Number: 64-00-6
Page 4 of 4
PHENOL, 3-(l-METHYLETHYL)-, METHYLCARBAMATE
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. Remove and isolate contaminated clothing and shoes at the
site. In case of contact with material, immediately flush skin or eyes
with running water for at least IS minutes. Keep victim quiet and maintain
normal body temperature. Effects may be delayed; keep victim under
observation (DOT 1984, Guide 55).
COMMENTS:
Sources searched but no information found:
Weiss 1980
Buchel 1983
Gosselin 1984
Merck 1983
Weast 1979
-------
CAS Registry Number: 64-86-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - COLCHICINE
CAS Registry Number: 64-86-8
Synonyms: 7-alpha-H-Colchicine; Acetamide, N-(5,6,7,9-Tetrahydro-1,2,3,10-
Tetramethoxy-9-oxobenzo[a]heptalen-7-yl); Benzo[a]heptalen-9(5H)-one,
7-acetamido-6,7-dihydro-l,2,3,10-tetramethoxy-; Colchicenos; Colchisol; Colcin;
Colsaloid; Condylon; N-Acetyl Trimethylcolchicinic acid, Methyl Ether; NSC 757
Chemical Formula: C22H25NO6
Molecular Weight: 399.43
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlo oral (dog,
cat) 0.125 mg/kg (*NIOSH/RTECS 1985).
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O»1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 288-302°F, 142-150°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g dissolves in 22 ml (*Merck 1976)
Appearance and Odor: Odorless or nearly so (*Hawlcy 1977); pale yellow
needles or powder; darkens on exposure to light (*Merck 1976).
-------
CAS Registry Number: 64-86-8
Page 2 of 3
COLCHICINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIHTLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg, i.e. less
than 7 drops for a 70 kg (150 Ib.) person (*Gosselin 1976). Death results
from respiratory arrest. The fatal dose varies considerably; as little as
7 mg of colchicine has proved fatal (*Goodman 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Slight fire potential (*Sax 1979). Material is a
drug (*SRI), with the following procedures for fires. Extinguish fire
using agent suitable for type of surrounding fire. Use water in flooding
quantities as fog. Use alcohol foam, carbon dioxide or dry chemical
(Student 1981, p. 215).
Special Fire Fighting Procedures: For drugs, solid, n.o.s., avoid
breathing dusts and fumes from burning material. Keep upwind. Wear boots,
protective gloves, and goggles (Student 1981, p. 215).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Clarke 1975)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
-------
• CAS Registry Number: 64-86-8
Page 3 of 3
COLCHICINE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Colchicine is a drug used to treat gouty arthritis, pseudogout, sarcoidal
arthritis and calcific tendinitis (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Precautions for drugs, solid, n.o.s., include the following. Avoid
breathing dusts, and fumes from burning materials. Keep upwind.
Avoid bodily contact with the material. Wear full protective clothing.
Wash away any material which may have contacted the body with
copious amounts of water or soap and water (Student 1981, p. 215).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
>
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Burning of throat and skin are prominent
symptoms. Nausea, vomiting, diarrhea and abdominal pain may occur several
hours after exposure. Shock occurs because of extensive vascular damage.
Kidney damage resulting in bloody urine and diminished urine output may
occur (*Goodman 1975).
Emergency and First Aid Procedures: This material is an alkaloid (Merck
1983, p. 352); first aid for alkaloid exposure is as follows: move victim
to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed; keep victim under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 65-30-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NICOTINE SULFATE
CAS Registry Number: 65-30-5
Synonyms: (S)-3-(l-Methyl-2-Pyrrolidinyl)Pyridine Sulfate (2:1); L-l-
Methyl-2-(3-Pyridyl)-Pyrrolidine Sulfate; L-3-( 1 -Methyl-2-Pyrrolidyl)Pyridine
Sulfate; Black Leaf 40; Nicotine Sulfate, Solid; Nicotine, Sulfate (2:1);
Pyridine, 3-(l-Methyl-2-Pyrrolidinyl)-, (S)-, Sulfate (2:1); Pyrrolidine,
l-Methyl-2-(3-Pyridyl)-, Sulfate
Chemical Formula: (C10H14N2)2.H2SO4
Molecular Weight: 422.56
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mice) 8.55 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.15 at 20°C (solid) (*CHRIS 1978)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR-1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in water (*Merck 1976)
-------
CAS Registry Number: 65-30-5
Page 2 of 4
NICOTINE SULFATE
SECTION II Continued)
Appearance and Odor: A six-sided tablet (*Merck 1976) or white crystals;
(40% solution - Black Leaf Forty) (Hawley 1981, p. 727).
SECTION III - HEALTH HAZARD DATA
OSHA PEL; Not Found
ACGIH TLV: TWA 0.5 mg (nicotineVm3; STEL 1.5 mg (nicotine)/m3 (skin)
(*ACGIH 1982)
IDLH: Not Found
Other Limits Recommended: TWA for nicotine: 0.5 mg/ms (skin) (OSHA 1984,
p. 663).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg (less than
7 drops) for a 70 kg (150 Ib.) person (*Gosselin 1976). Death is possible
from respiratory failure caused by paralysis of the respiratory muscles
(*Goodman 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: As for nicotine, extinguish with alcohol foam, dry
chemical, or carbon dioxide (Sax 1984, p. 1997). Large fires can be
extinguished with water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Dike fire control water; do not
scatter the material (*DOT 1984).
Unusual Fire and Explosion Hazards: As for nicotine, moderate explosion
hazard when exposed to heat or flame (*Sax 1975).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 65-30-5
Page 3 of 4
NICOTINE SULFATE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Menzie 1969)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1998)
Incompatibility (Materials to Avoid): (Non-Specific — Nicotine) Avoid
oxidizing materials (Sax 1984, p. 1997).
Hazardous Decomposition or Byproducts: When heated to decomposition,
emits highly toxic fumes of sulfur oxides and organic fumes (Sax 1984, p.
1998).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as an insecticide (*Merck 1976) and in veterinary medicine as an
anthelmintic and external parasiticide (*Garner 1967).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
To clean up, do not touch spilled material; stop leak if possible. Use
water spray to reduce vapors. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for disposal.
Small dry spill: with clean shovel place material into clean, dry
container and cover; move containers from spill area. Large spills: dike
far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Onset of acute poisoning is rapid.
Symptoms include nausea, salivation, abdominal pain, vomiting, diarrhea,
cold sweat, headache, dizziness, disturbed hearing and vision, mental
confusion, marked weakness, faintness and prostration, lowered blood
pressure, difficult breathing, and weak, rapid and irregular pulse
(*Goodman 1980). Inhalation irritates nose and throat. The liquid form
irritates the eyes and (on prolonged contact) skin (*CHRIS 1978).
-------
CAS Registry Number: 65-30-5
Page 4 of 4
NICOTINE SULFATE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim under
observation (*DOT 1984).
-------
CAS Registry Number: 66-81-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CYCLOHEXIMIDE
CAS Registry Number: 66-81-9
Synonyms: Glutarimide, 3-(2-(3,5-Dimethyl-2-Oxocyclohexyl)-2- Hydroxycthyl)-;
2,6-Piperidinedione, 4-(2-(3,5-Dimethyl-2-Oxocyclohexyl)- 2-Hydroxyethyl)-
(1S-(1 alpha(S*), 3 alpha, 5 beta))-; Acti-aid; Acti-Dione-PM (-RZ, -BR, & -S);
Actidion; Actidione; Actidione PM; Actispray; beta-(2-(3,5-
Dimethyl-2-Oxocyclohexyl)-2-Hydroxyethyl)Glutarimide; Hizarocin; Kaken;
Naramycin; Naramycin A; Neocycloheximide; NSC-185; TZA; U 4527
Chemical Formula: C15H2SNO4
Molecular Weight: 281.34
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 2 mg/kg (*NIOSH/RTECS 1985).
TPQ: 100/10,000 (pounds)
•*
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O»1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 247-250°F, 119.5-121 °C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Moderately soluble (Sax 1984, p. 833); 21 g/liter at
36°F, 2°C (*Merck 1976)
-------
CAS Registry Number: 66-81-9
Page 2 of 3
CYCLOHEXIMIDE
SECTION II (continued)
Appearance and Odor: Colorless crystals (*Spencer 1973).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose in humans is 5-50 mg/kg, or 7 drops to
1 teaspoonful for a 150-lb. person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LELr Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Fungicides, Poison B Solid) Use
agent suitable for surrounding fire. Use alcohol foam, carbon dioxide, or
dry chemical. Use water in flooding quantities as fog (Student 1981, p.
259).
Special Fire Fighting Procedures: (Non-Specific — Fungicides, Poison B
Solid) Avoid breathing dusts and fumes from burning material. Keep
upwind. Wear self-contained breathing apparatus. Avoid bodily contact
with the material. Wear full protective clothing (Student 1981, p. 259).
Unusual Fire and Explosion Hazards: When exposed to heat, it emits toxic
fumes, including nitrogen oxides (Sax 1984, p. 833).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1976)
-------
CAS Registry Number: 66-81-9
Page 3 of 3
CYCLOHEXIMIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When exposed to heat, it emits
toxic fumes, including nitrogen oxides (Sax 1984, p. 833).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a fungicide (*Merck 1976), and as a medication in
cancer therapy (*Rumack 1975 to Present).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Fungicides, Poison B Solid) Avoid breathing dusts. Keep
upwind. Avoid bodily contact with the material (Student 1981, p. 259).
Material is rapidly inactivated at room temperature by dilute alkali
(*Merck 1976).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 66-81-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
CYCLOHEXIMIDE
(66-81-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless crystals.
Commercial Forms - Oil solution, wettable powder, water-soluble tablets.
Uses - Chemotherapy, turf disease control, plant growth regulation, fungicide.
Other Names - Acti-aid, Actidione, Actispray, glutarimide, 3-(2-(3,5-dimethyl-
2-oxocyclohexyl)-2-hydroxyethyl)-; Hizarocin, Kaken, Naramycin A.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
hydrocortisone, atropine.
Signs and Symptoms of Acute Cycloheximide Exposure:
Warning: Effects may be delayed for 6 to 24 hours. Caution is advised.
Signs and symptoms of acute exposure to cycloheximide may include increased
salivation, nausea, vomiting, diarrhea, and dark, bloodstained stools. Dermal
effects may range from erythema (redness) to sloughing. Central nervous system
excitement, including tremor, may be noted. Liver and kidney damage, coma, and
cardiovascular collapse are also possible.
-------
EFATG
CAS Registry Number: 66-81-9
Page 2 of 3
CYCLOHEXIMIDE
Emergency Life-Support Procedures:
Acute exposure to cycloheximide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to cycloheximide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to cycloheximide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 66-81-9
Page 3 of 3
CYCLOHEXIMIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of cycloheximide is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of cycloheximide may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 67-66-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHLOROFORM
CAS Registry Number: 67-66-3
Synonyms: Formyl Trichloride; Freon 20; Methane, Trichloro-; Methane
Trichloride; Methenyl Chloride; Methenyl Trichloride; Methyl Trichloride;
NCI-CO2686; R-20; R 20 (Refrigerant); TCM; Trichloroform; Trichloromethane
Chemical Formula: CHC13
Molecular Weight: 119.39
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 10,000 (pounds)
RQ: 5000 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 143°F, 61.7°C (*Weast 1979)
Specific Gravity (H2O=1): 1.4832 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 100 at 10.4°C (*Sax 1979)
Melting Point: -82.3°F, -63.5°C (*Weast 1979)
Vapor Density (AIR=1): 4.12 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): (Carbon Tetrachloride = 1) 1.18
('General Electric Co. 1979, MSDS #315)
Solubility in Water: 1 mL/200 mL at 25°C (*Merck 1976)
-------
CAS Registry Number: 67-66-3
Page 2 of 4
CHLOROFORM
SECTION II (continued)
Appearance and Odor: A clear, colorless and mobile liquid with a
characteristic odor (*IARC 1972-1985).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 50 ppm (240 mg/m3) (NIOSH 1987, p. 80)
ACGIH TLV: TWA 10 ppm (50 mg/m8) (ACGIH 1986-87, p. 13)
IDLH: 1,000 ppm (NIOSH/OSHA 1978, p. 68)
Other Limits Recommended: NIOSH: 2 ppm 60-minute ceiling; potential
occupational carcinogen (NIOSH 1897, p. 80 and Appendix A). Industrial
substance suspect of carcinogenic potential for humans (ACGIH 1985, p. 42).
EEGL 100.0 ppm (60 minutes) (NRC 1984a, pp. 57-76).
Routes of Entry: Inhalation: Yes (*NIOSH 1974)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*ITI 1982)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
moderately toxic. Probable oral lethal dose for humans is 0.5 to 5 g/kg
(between 1 ounce and 1 pint) for a 150 Ib. person. The mean lethal dose is
probably near 1 fluid ounce (44 g) (*Gosselin 1976). It is a human
suspected carcinogen (*IARC 1972-1985). Also, it is a central nervous
system depressant and a gastrointestinal irritant (*Challen PS et al. 1958.
Br J Ind Med 15:243). It has caused rapid death attributable to cardiac
arrest and delayed death from liver and kidney damage (*IARC 1972-1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): None (*General Electric Co. 1979, MSDS #315)
Flammable Limits:
LEL: None ('General Electric Co. 1979, MSDS #315)
UEL: None ('General Electric Co. 1979, MSDS #315)
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog or foam (*DOT 1984).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and special protective clothing. Move container from fire area. Fight
fire from maximum distance. Dike fire control water for later disposal; do
not scatter the material (*DOT 1984).
Unusual Fire and Explosion Hazards: Container may explode in the heat of
fire (*DOT 1984). When heated it liberates phosgene (*ITI 1982); hydrogen
chloride, chlorine and toxic and corrosive oxides of carbon and chlorine
('General Electric Co. 1979, MSDS #315).
-------
CAS Registry Number: 67-66-3
Page 3 of 4
CHLOROFORM
SECTION IV (continued)
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*CHRIS 1978)
Conditions to Avoid: It develops acidity from prolonged exposure to
air and light (*General Electric Co. 1979, MSDS #315).
Incompatibility (Materials to Avoid): Chloroform explodes when in contact
with aluminum powder or magnesium powder or with alkali metals (e.g.,
lithium, sodium, and potassium) (*NFPA 1978) and dinitrogen tetroxide. It
reacts vigorously with acetone in the presence of potassium hydroxide or
calcium hydroxide (*Bretherick 1975). It is oxidized by strong oxidizers
such as chromic acid forming phosgene and chlorine (*IARC 1972-1985). It
reacts vigorously with triisopropylphosphine (*Bretherick 1975).
Hazardous Decomposition or Byproducts: When heated, it emits hydrogen
chloride, chlorine, toxic and corrosive oxides of carbon and chlorine
(*General Electric Co. 1979, MSDS #315) and phosgene (*ITI 1982).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a grain fumigant; solvent for pesticides, adhesives (*IARC
1972-1985) fats, oils, rubbers, alkaloids, waxes (*Merck 1976); chemical
intermediate for dyes and pesticides; and a component of cough syrups,
toothpastes, and linaments (*SRI). Not registered as a pesticide in the
U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING .AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remote and isolate contaminated clothing at the site. Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors. Small spills: take up with sand or other
non-combustible absorbent materal and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (*DOT
1984).
-------
CAS Registry Number: 67-66-3
Page 4 of 4
CHLOROFORM
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene POOR/LIMITED*
CPE POOR/MANY
Neoprene POOR/MANY
Nitrile POOR/MANY
PE POOR/MANY
PVC POOR/MANY
Saranex POOR/MANY
Teflon GOOD/LIMITED
Viton GOOD/LIMITED
Viton/Chlorobutyl GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of acute exposure include
fainting sensation, vomiting, dizziness, salivation, nausea, fatigue, and
headache (*ACGIH 1971-1979). Other symptoms are respiratory depression,
coma, kidney damage, and liver damage (*IARC 1972-1985). Liquid in the eye
causes tearing and conjunctivitis (*Grant 1974). Symptoms of chronic
exposure include loss of appetite, hallucinations, moodiness and physical
and mental sluggishness (*NIOSH 1974. Criteria for a recommended standard
occupational exposure to chloroform. DHEW Pub NIOSH 75-114).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; if0^> victim
under observation (*DOT 1984).
-------
CAS Registry Number: 70-69-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: June 22, 1987
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPIOPHENONE, 4'-AMINO-
CAS Registry Number: 70-69-9
Synonyms: l-(4-Aminophenyl)-l-Propanone; p-Aminopropiophenone; PAPP;
Paraminopropiophenone; USAF UCTL-1856
Chemical Formula: C9HUNO
Molecular Weight: 149.21
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (cat)
5.6 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O»1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 284°F, 140°C (Merck 1983, p. 70)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Merck 1983, p. 70)
Appearance and Odor: Yellow needles (Merck 1983, p. 70)
-------
CAS Registry Number: 70-69-9
Page 2 of 3
PROPIOPHENONE, 4'-AMTNO-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 245)
Health Hazards (Acute, Delayed, and Chronic): Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 70-69-9
Page 3 of 3
PROPIOPHENONE, 4'-AMINO-
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Ingestion of large doses can cause
cyanosis (Sax 1984, p. 245)
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Farm Chemicals Handbook 1984
Hayes 1982
Worthing 1979
Verschueren 1983
Clayton and Clayton 1981-1982
Weiss 1980
Goodman and Oilman 1985
Gosselin 1984
Hawley 1981
-------
CAS Registry Number: 71-63-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIGITOXIN
CAS Registry Number: 71-63-6
Synonyms: Acedoxin; Card-20(22)-Enolide, 3-((O-2,6-Dideoxy-beta-D-Ribo-
Hexopyranosyl-(Hexopyranosyl-(l-4)-2,6-Dideoxy-beta-D-Ribo-Hexopyranosyl)oxy)
-14-Hydroxy-, (3beta, 5beta)-; Cardigin; Carditoxin; Cristapurat; Crystalline
Digitalin; Crystodigin; Digilong; Digimed; Digimerck; Digisidin; Digitalin;
Digitaline Cristallisee; Digitaline Nativelle; Digitoksim; Digitophyllin;
Digitoxigenin Tridigitoxoside; Ditaven; Glucodigin; Lanatoxin; Myodigin;
Purodigin; Purpurid; Unidigin
Chemical Formula: C41H64O13
Molecular Weight: 764.92
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (cat)
0.18 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 493-495°F, 256-257°C (when anhydrous) (*Merck 1976)
Vapor Density (AIR=»1): Not Found
Evaporation Rate (Butyl acetate-1): Not Found
Solubility in Water: 1 g in 100 liters at 20°C (*Merck 1976)
-------
CAS Registry Number: 71-63-6
Page 2 of 4
DIGITOXIN
SECTION II (continued)
Appearance and Odor: White or pale buff microcrystalline powder (*Osol
1975); odorless (Merck 1983, p. 353)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Material is bioactive and
capable of causing cardiac arrythmias and electrolyte imbalances that may
be fatal. Death is due to ventricular fibrillation or cardiac standstill
(*Gosselin 1976). Material has a high toxicity hazard rating; it may cause
death or permanent injury after a very short exposure (*Sax 1979). It is
classified as super toxic; an estimated single lethal dose is 3-10 mg
(Gosselin 1984, p. 11-252).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Drugs or Medicines, Solid,
n.o.s.) Extinguish fire using agent suitable for type of surrounding fire
(material itself burns with difficulty.) Use water in flooding quantities
as fog. Use alcohol foam, carbon dioxide or dry chemical (Student 1981,
p. 215).
Special Fire Fighting Procedures: (Non-Specific — Drugs or Medicines,
Solid, n.o.s.) Avoid breathing dusts and fumes from burning material.
Keep upwind. Wear boots, protective gloves, and goggles (Student 1981, p.
216).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and irritating fumes (Sax 1984, p. 1035).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 71-63-6
Page 3 of 4
DIGITOXIN
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Material is a cardiotonic drug (*Goodman 1975).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Drugs or Medicines, Solids, n.o.s.) Keep upwind.
Avoid bodily contact with the material. Wear full protective clothing.
Wash away any material which may have contacted the body with copious
amounts of water or soap and water (Student 1981, p. 216).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea and vomiting, headache, malaise,
fatigue, weakness, drowsiness, abdominal discomfort are symptomatic of
toxicity. Visual disturbances (reduction in visual acuity, illusions of
flickering or shimmering lights, abnormal color vision) and emotional
disorders (including confusion, disorientation, aphasia, delirium,
hallucinations, and rarely convulsions) are also possible toxic effects
(*Gosselin 1976; *Grant 1974).
Emergency and First Aid Procedures: (Non-Specific -- Medicines, n.o.s.)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least IS minutes. Remove and isolate contaminated clothing
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CAS Registry Number: 71-63-6
Page 4 of 4
DIGITOXIN
SECTION IX (continued)
and shoes at the site. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 11).
-------
CAS Registry Number: 72-20-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ENDRIN
CAS Registry Number: 72-20-8
Synonyms: 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-Hexachloro-6,7-Epoxy-
l,4,4a,5,6,7,8,8a-Octahydro-,endo,endo-; Compound 269; Endrex; Endricol; ENT
17,251; Experimental Insecticide 269; Hexachloroepoxyoctahydro-endo,endo-
Dimethanonaphthalene; Hexadrin; Mendrin; NCI-C00157; SD 3419; Oktanex; EN 57;
2,7:3,6-Dimethanonaphth[2,3-b]Oxirene, 3,4,5,6,9,9-Hexachloro-1 a,2,2a,
3,6,6a,7,7a-Octahydro-, (la.alpha., 2.beta., 2a.beta., 3.alpha., 6.alpha.,
6a.beta., 7.beta., 7a.alpha.)-; Nendrin; 1,2,3,4,10,10-Hexachloro-6,7-epoxy-
l,4,4a,5,6,7,8,8a-octahydro-endo,endo-l,4:5,8-dimethanonaphthalene; 1,2,3,4,
10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-endo-1,4-endo-5,8-
dimethanonaphthalene; 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-
octahydro-l,4:5,8-endo,endo-dimethanonaphthalene; NCI 01565; C00157; Isodrin
Epoxide; Endrical
Chemical Formula: C12H8C16O
Molecular Weight: 380.90
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 1.37 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.7 at 68°F, 20°C (*USEPA 1980)
Vapor Pressure (mmHg): 0.0000002 at 77°F, 25°C (*Worthing 1979)
Melting Point: Decomposes at 473°F, 245°C (Merck 1983, p. 517)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 72-20-8
Page 2 of 4
ENDRIN
SECTION II (continued)
Evaporation Rate (Butyl acetate-1): Not Found
Solubility in Water: Practically insoluble (*IARC 1972-1985)
Appearance and Odor: White, crystalline solid; light tan color for
technical grade (*NFPA 1978). Odorless ("CHRIS 1978) or mild chemical odor
for technical grade (*IARC 1972-1985).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 mg/m3 (skin) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.1 mg/m3 (skin) (ACGIH 1986-87, p.18)
IDLH: 200 mg/m3 (*NIH EPA, OHM/TADS 1984)
Other Limits Recommended: STEL 0.5 mg/m3 for 30 minutes (Weiss 1980, p.
402)
Routes of Entry: Inhalation: Yes ("USEPA 1980)
Skin: Yes (*NFPA 1978)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic (*Gosselin 1976). It is rapidly absorbed through the skin (*NFPA
1978). Symptoms appear between 20 minutes and 12 hours after exposure
(*Gosselin 1976). There is evidence that this material may cause
chromosomal damage (*USEPA 1980). Doses of 1 mg/kg can cause symptoms (Sax
1984, p. 1278). It is a suspected carcinogen (Hawley 1981, p. 410). Also,
it is a central nervous system depressant and hepatotoxin (Farm Chemicals
Handbook 1984, p. C-93).
Medical Conditions Generally Aggravated by Exposure: Pregnant women are
considered to be at special risk (*USEPA 1980).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Commercial product may contain flammable
liquid with flashpoint 80°F, 27°C (*NIH EPA, OHM/TADS 1984)
Flammable Limits:
LEL: 1.1% (commercial product) (Weiss 1980, p. 402)
UEL: 7.0% (commercial product) (Weiss 1980, p. 402)
Extinguishing Methods: Use dry chemical, foam, carbon dioxide ("CHRIS
1978), water spray for solution (*NFPA 1978). Small fires: dry chemical,
carbon dioxide, water spray, or foam. Large fires: water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Use water to keep fire-exposed
containers cool (*NFPA 1978). Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
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CAS Registry Number: 72-20-8
Page 3 of 4
ENDRIN
SECTION IV (continued)
spaces before entering them. Wear positive pressure breathing apparatus
and special protective clothing. Remove and isolate contaminated clothing
at the site. Move container from fire area if you can do it without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Toxic hydrogen chloride and phosgene
may be generated when solution burns (*CHRIS 1978).
NFPA Flammability Rating: 1 (solution); 0 (dry)
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*USEPA 1980)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers, strong acids
(*NIH EPA, OHM/TADS 1984), and parathion (Sax 1984, p. 1279)
Hazardous Decomposition or Byproducts: Toxic hydrogen chloride and
phosgene may be generated when solutions burn (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not found
SECTION VI - USE INFORMATION
This material is used primarily as an insecticide for field crops
(*Worthing 1979). Only cotton and bird perch uses registered in the U.S.
(USEPA/Pesticide Index 1985).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
For leaks or spills, use water spray to disperse vapor and to flush spills
(*NFPA 1978). Liquid containing this material should be absorbed in
vermiculite, dry sand, earth (*NIOSH/OSHA 1981). Do not touch spilled
material; stop leak if you can do it without risk. Small dry spills: with
clean shovel place material into clean, dry container and cover; move con-
tainers from spill area. Large spills: dike far ahead of spill for later
disposal. Keep unnecessary people away; isolate hazard area and deny
entry. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site (DOT 1984, Guide 55).
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CAS Registry Number: 72-20-8
Page 4 of 4
ENDRIN
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: It can cause death by respiratory arrest.
Symptoms include headache, nausea, vomiting, dizziness, tremors,
convulsions, loss of consciousness, rise in blood pressure, fever, frothing
of the mouth, deafness, coma, and death (*Gosselin 1976, Gosselin 1984, pp.
11-285, III-143).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 74-83-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL BROMIDE
CAS Registry Number: 74-83-9
Synonyms: Brom-o-gas; Bromomethane; Curafume; Dowfume MC-2 Soil Fumigant;
Dowfume MC-33; Edco; Embafume; Halon 1001; Haltox; Iscobrome; Kayafume; MB;
MBX; MEBR; Metaf ume; Methane, Bromo-; Methogas; Monobromomethane; Pestmaster;
Prof ume; R 40B1; Rotox; Terabol; Terr-o-gas 100; Zytox
Chemical Formula: CH3Br
Molecular Weight: 94.95
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 38.4°F, 3.56°C (*Weast 1979)
Specific Gravity (H2O=1): Liquid: 1.730 at 0°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 1420 at 20°C (*Merck 1976)
Melting Point: -136°F, -93.6°C (*Merck 1976)
Vapor Density (AIR»1): 3.27 (*NFPA 1978)
Evaporation Rate (Butyl acetate=»l): Not Found
Solubility in Water: 1.34 g/100 g at 25°C (*Worthing 1979)
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CAS Registry Number: 74-83-9
Page 2 of 4
METHYL BROMIDE
SECTION II (continued)
Appearance and Odor: Colorless gas; usually odorless, but has a sweetish
chloroform-like odor at high concentrations (*Merck 1976).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling Concentration 80 mg/ms (20 ppm) (NIOSH 1987,p. 158)
ACGIH TLV: TWA 20 mg/ms (5 ppm) (ACGIH 1986-87, p.23)
IDLH: 2,000 ppm (NIOSH/OSHA 1978, p. 126)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Gosselin 1976)
Skin: Yes (*Gosselin 1976)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Methyl bromide is a
dangerous cumulative poison with delayed symptoms of central nervous system
intoxication that may appear as long as several months after exposure
(*White-Stevens 1971). High concentrations can produce fatal pulmonary
edema. Chronic exposure can cause central nervous system depression and
kidney injury (*Merck 1976). It may cause severe and permanent brain
damage. Severe neurological signs may appear when there is a sudden
exposure to high concentrations following continuous slight exposure
(*Encyc Occupat Health and Safety 1971). Methyl bromide has practically no
odor or irritating effects and therefore no warning, even at hazardous
concentrations (*Clayton and Clayton 1981-82).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): None (*Sax 1979)
Flammable Limits:
LEL: 10% (*Sax 1979)
UEL: 16% (*Sax 1979)
Extinguishing Methods: Non-flammable in air; burns in oxygen (*Merck
1976). Use water spray, foam, carbon dioxide, or dry chemical (*NFPA
1978).
Special Fire Fighting Procedures: Full protective clothing, including
self-contained breathing apparatus, coat, pants, gloves, boots, and bands
around legs, arms, and waist should be provided. No skin surface should be
exposed (*NFPA 1978). Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of bromides (*Sax 1979).
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CAS Registry Number. 74-83-9
Page 3 of 4
METHYL BROMIDE
SECTION IV (continued)
NFPA Flammability Rating: 1
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of bromides (*Sax 1979).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 603)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an insecticide, rodenticide, fumigant, and
nematocide; as a chemical intermediate (*SRI); and as a fire extinguishing
agent (""Clayton and Clayton 1981-82).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Remove all ignition sources. Ventilate area of spill or leak,
stop flow of gas or remove leaking cylinder to open air and
repair leak or allow cylinder to empty. If material is in the
liquid form, allow it to vaporize (*NIOSH/OSHA 1981). Stay
upwind, keep out of low areas. Use water spray to reduce vapors
(DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Neoprene GOOD/LIMITED*
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CAS Registry Number: 74-83-9
Page 4 of 4
METHYL BROMIDE
SECTION VIII (continued)
Nitrile GOOD/LIMITED*
PE POOR/LIMITED
PVC POOR/LIMITED*
Saranex GOOD/LIMITED
Viton GOOD/LIMITED*
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 74-83-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHYL BROMIDE
(74-83-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless, transparent, easily liquefied gas, or volatile liquid.
Odor - Usually odorless, chloroformlike odor at higher concentrations.
Commercial Forms - 98% pure liquid or gas in steel cylinders.
Uses - Organic synthesis, fumigation, fire extinguishing, oil extraction from
organic matter, pesticides, ionization chambers.
Materials to Avoid - Metals, oxidizers.
Other Names - Bromomethane, Curafume, Dowfume, Embafume, Haltox, Iscobrome,
Kayafume, Metafume, Methogas, Monobromomethane, Pestmaste, Profume, Rotox,
Terabol, Zytox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, dimercaprol, diazepam, phenytoin, phenobarbital,
aminophylline, furosemide.
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EFATG
CAS Registry Number: 74-83-9
Page 2 of 3
METHYL BROMIDE
Signs and Symptoms of Acute Methyl Bromide Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and symptoms of acute exposure to methyl bromide may be severe and
include tremors, convulsions, brain hemorrhage, paralysis, coma, and permanent
brain damage. Respiratory effects include cough, tachypnea (rapid respiratory
rate), pulmonary edema, and respiratory collapse. Cyanosis (blue tint to the
skin and mucous membranes), pallor, ventricular fibrillation, and circulatory
collapse may also occur. Lethargy, profound weakness, headache, dizziness,
mental confusion, slurring of speech, staggering gait, and blurred or double
vision are often found.
Gastrointestinal signs and symptoms include nausea, vomiting, abdominal pain,
and anorexia. Oliguria (scanty urination), anuria (lack of urine formation),
kidney hemorrhage, and kidney failure may occur. Contact with methyl bromide
may cause dermatitis (red, inflamed skin) and conjunctivitis (red, inflamed
eyes).
Emergency Life-Support Procedures:
Acute exposure to methyl bromide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methyl bromide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other, invasive
procedures.
4. Transport to a health care facility.
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EFATG
CAS Registry Number: 74-83-9
Page 3 of 3
METHYL BROMIDE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methyl bromide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
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CAS Registry Number: 74-90-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - HYDROCYANIC ACID
CAS Registry Number: 74-90-8
Synonyms: Hydrogen Cyanide; Prussic Acid; Aero Liquid HCN; Cyclon; Cyclone
B; Evercyn; Formic Anammonide; Formonitrile; Zaclondiscoids
Chemical Formula: HCN
Molecular Weight: 27.03
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.357 mg/liter/5 minutes (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 78.1°F, 25.6°C (*Merck 1976)
Specific Gravity (H2O«1): 0.699 (liquid) (*Weast.l983)
Vapor Pressure (mmHg): 630 (*White-Stevens 1971)
Melting Point: 7.9°F, -13.4°C (*Merck 1983)
Vapor Density (AIR-1): 0.901 g/1 (*Weast 1983)
Evaporation Rate (Butyl acetate=»l): Not Found
Solubility in Water: Miscible with water (*Merck 1976)
Appearance and Odor: Colorless gas or liquid; bitter almond odor (*Merck
1976; *CHRIS 1978)
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CAS Registry Number: 74-90-8
Page 2 of 4
HYDROCYANIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 10 ppm (11 mg/m3), as cyanide (NIOSH 1987 p. 138)
ACGIH TLV: Ceiling 10 mg/m3 (10 ppm) (skin) (ACGIH 1986-87 p. 20)
IDLH: 50 ppm, as cyanide (NIOSH 1987, p. 138)
Other Limits Recommended: NIOSH: 5 mg/m3 (4.7 ppm) (CN) 10 minute ceiling
(NIOSH 1987, p. 138)
Routes of Entry: Inhalation: Yes (*Goodman 1975)
Skin: Yes (*Encyc Occupat Health and Safety 1983)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): It is super toxic.
Breathing in a small amount of the gas or swallowing a very small amount
may be fatal (*NFPA 1978; *Gosselin 1976). Average fatal dose is 50-60 mg.
A few minutes of exposure to 300 ppm may result in death. Exposure to 150
ppm for 1/2 to 1 hour may endanger life (Merck 1983, p. 696).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 0°F, -18°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 5.6% (*NFPA 1978)
UEL: 40.0% (*NFPA 1978)
Extinguishing Methods: Use dry chemicals, alcohol foam, or carbon dioxide
(*NFPA 1978). Small fires: let burn unless leak can be stopped
immediately. Large fires: water spray, fog or foam. Move container from
fire area if you can do it without risk. Stay away from ends of tanks.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire. Cool container with water using
unmanned device until well after fire is out. Isolate area until gas has
dispersed (*DOT 1984).
Special Fire Fighting Procedures: Firefighting should be done from a safe
distance. A few whiffs of gas, or liquid penetrating firefighter's
protective clothing, could be fatal. Only special protective clothing
should be worn. Water spray should be used to keep containers cool (*NFPA
1978). Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Evacuate area endangered by gas. Isolate for 1/2
mile in all directions if tank car or truck is involved in fire (*DOT
1984).
Unusual Fire and Explosion Hazards: Unstabilized hydrocyanic acid may
polymerize spontaneously with explosive violence (*Hawley 1981). Flashback
along vapor trail may occur (*CHRIS 1978). The explosion hazard is severe
when this material is exposed to heat, flame, or oxidizers (*Sax 1975). It
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CAS Registry Number: 74-90-8
Page 3 of 4
HYDROCYANIC ACID
SECTION IV (continued)
forms explosive mixtures with air, and will react with water, steam, acid,
or acid fumes to produce highly toxic fumes of cyanides. It may decompose
explosively upon contact with alkaline material (Sax 1984, p. 1548).
NFPA Flammability Rating: 4
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Hawley 1981)
Stable:
Conditions to Avoid: Hydrocyanic acid solution is sensitive to light
(*Hawley 1977). It may become unstable and subject to explosion if
stored for an extended time or exposed to high temperature and pressure
("CHRIS 1978). Avoid heat, flame or oxidizers (Sax 1984, p. 1548).
Incompatibility (Materials to Avoid): Acetylaldehyde, alkaline materials,
oxidizers, water, steam, acid, and acid fumes (Sax 1984, p. 1548)
Hazardous Decomposition or Byproducts: Toxic cyanide fumes (Sax 1984, p.
1548)
Hazardous Polymerization: May Occur: Yes (*Hawley 1981)
May Not Occur:
Conditions to Avoid: Unstabilized hydrocyanic acid may polymerize
spontaneously with explosive violence (*Hawley 1981). Can polymerize
at 50-60°C or when catalyzed with traces of alkali (Sax 1984, p.
1548).
SECTION VI - USE INFORMATION
j Hydrogen cyanide is used as a rodent poison and as a fumigant (*Rossoff
*1974). It is a chemical intermediate in the manufacture of acrylates,
methacrylates, hexamethylenediamine, nitriles, and other materials (*Patty
1963). It is also used in metal polishes, electroplating solutions, and
metallurgical and photographic processes (*Gosselin 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering. Use water spray to reduce vapors. Do not touch spilled
material; stop leak if you can do it without risk. Shut off ignition;
no flares, smoking, or flames in hazard area. Isolate area until gas
dispersed (*DOT 1984)
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.CAS Registry Number: 74-90-8
Page 4 of 4
HYDROCYANIC ACID
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Neoprene GOOD/LIMITED*
PE GOOD/LIMITED
PVC POOR/LIMITED
Viton GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 74-90-8
Page 1 of 4
Emergency First Aid Treatment Guide
for
HYDROCYANIC ACID (HYDROGEN CYANIDE)
(74-90-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Hydrocyanic acid toxicity can occur via ingestion, dermal/eye
contact, or inhalation; death may occur within minutes. IMMEDIATELY begin
administering 100% oxygen and RUSH victims to a health care facility.
Substance Characteristics:
Pure Forms - Colorless gas or water-white liquid below -13 degrees C
(8 degrees F).
Odor - Bitter, almondlike.
Commercial Forms - 96 to 99% pure in 2, 5, and 10% solutions with a stabilizer
in bottles, steel cylinders, and tank cars.
Uses - Rodenticide, fumigant, . chemical intermediate, metallurgy and
photography, constituent in metal polishes and electroplating solutions.
Other Names - Cyclon, formonitrile, hydrogen cyanide, prussic acid.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulfate), sodium
bicarbonate, diazepam, phenytoin.
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EFATG
CAS Registry Number: 74-90-8
Page 2 of 4
HYDROCYANIC ACID (HYDROGEN CYANIDE)
Signs and Symptoms of Acute Hydrocyanic Acid Exposure:
Warning: Hydrocyanic acid may be fatal if inhaled, swallowed, or absorbed
through skin or mucous membranes.- Caution is advised.
Signs and symptoms of acute exposure to hydrocyanic acid may include
hypertension (high blood pressure) and tachycardia (rapid heart rate), followed
by hypotension (low blood pressure) and bradycardia (slow heart rate). Cherry
red mucous membranes and blood may be noted. Cardiac arrhythmias and other
cardiac abnormalities are common. Cyanosis (blue tint to the skin and mucous
membranes) may be observed.
Weakness, headache, vertigo (dizziness), agitation, giddiness, salivation,
nausea, and vomiting, may be followed by combative behavior, convulsions,
paralysis, protruding eyeballs, dilated and unreactive pupils, and coma.
Tachypnea (rapid, shallow respirations) or hyperpnea (rapid, deep respirations)
may be followed by respiratory depression. Lung hemorrhage and pulmonary edema
may also occur.
Hydrocyanic acid is may be irritating to the skin, eyes, and mucous membranes.
Lacrimation (tearing) and a burning sensation of the mouth and throat are
common.
Emergency Life-Support Procedures:
Acute exposure to hydrocyanic acid may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrocyanic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with hydrocyanic acid-
contaminated persons or their gastric contents can result in self-
poisoning.
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CAS Registry Number: 74-90-8
Page 3 of 4
HYDROCYANIC ACID (HYDROGEN CYANIDE)
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrocyanic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with hydrocyanic acid-
contaminated persons or their gastric contents can result in self-
poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with hydrocyanic acid-
contaminated persons or their gastric contents can result in self-
poisoning.
2. RUSH to a health care facility!
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CAS Registry Number: 74-90-8
Page 4 of 4
HYDROCYANIC ACID (HYDROGEN CYANIDE)
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
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CAS Registry Number: 74-93-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL MERCAPTAN
CAS Registry Number: 74-93-1
Synonyms: Mercaptomethane; Methanethiol; Methyl Sulfhydrate; Thiomethanol;
Thiomethyl Alcohol
Chemical Formula: CH4S
Molecular Weight: 48.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCSO inhalation
(mouse) 0.0065 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 42.7°F, 5.95°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8665 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at -90.7°C; 10 at -67.5°C; 40 at -49.2°C; 100 at
-34.8°C; 400 at -7.9°C; 760 at 6.8°C (*Weast 1979)
Melting Point: -189.4°F, -123°C (*Merck 1983)
Vapor Density (AIR-1): 1.66 (*Sax 1984)
Evaporation Rate (Butyl acetates!): Not Found
Solubility in Water: 23.30 g/liter (*Merck 1983)
Appearance and Odor: Water-white liquid when below boiling point, or
colorless gas (*Hawley 1981); odor of rotten cabbage (*Merck 1983)
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CAS Registry Number: 74-93-1
Page 2 of 4
METHYL MERCAPTAN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 20 mg/ms (10 ppm) 15 minute (NIOSH/OSHA 1978, p.
130)
ACGIH TLV: TWA 1 mg/m3 (0.5 ppm) (*ACGIH 1983)
IDLH: 400 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 618)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Can cause death by
respiratory paralysis (*ACGIH 1980). It is an eye and respiratory tract
irritant. Exposure results in pulmonary edema and hepatic and renal damage
(Clayton and Clayton 1981-82, p. 2067).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 0°F, -18°C (*Sunshine 1969)
Flammable Limits:
LEL: 3.9% (Weiss 1980, p. 618)
UEL: 21.8% (Weiss 1980, p. 618)
Extinguishing Methods: Small fires: let burn unless leak can be stopped
immediately. Large fires: water spray, fog, or foam. Move container from
fire area if you can do so without risk. Stay away from ends of tanks.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire. Cool container with water using
unmanned device until well after fire is out. Isolate area until gas has
dispersed (DOT 1984, Guide 13). Preferably let fire burn, stop gas flow.
Fires may be extinguished with dry chemical, foam, or carbon dioxide (Weiss
1980, p. 618).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Evacuate area endangered by
gas. Isolate for 1/2 mile in all directions if tank car or truck is
involved in fire (DOT 1984, Guide 13).
Unusual Fire and Explosion Hazards: Combustion produces irritating sulfur
dioxide. Flash back along vapor track may occur (*CHRIS 1978), Very
dangerous when exposed to heat, flame, or oxidizers. On decomposition it
emits highly toxic fumes of sulfur oxides. It will react with water, steam
or acids to produce toxic and flammable vapors; and can react vigorously
with oxidizing materials (Sax 1984, p. 1764).
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CAS Registry Number: 74-93-1
Page 3 of 4
METHYL MERCAPTAN
SECTION IV (continued)
NFPA Flammability Rating: 4
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*CHRIS 1978)
Conditions to Avoid: Direct sunlight, and areas of high fire hazards
(*Sax 1968)
Incompatibility (Materials to Avoid): Incompatible with mercuric oxide
and oxidizing materials (Sax 1984, p. 1764).
Hazardous Decomposition or Byproducts: Irritating sulfur dioxide is
produced upon combustion (Weiss 1980, p. 618). When heated to
decomposition, it emits highly toxic fumes and flammable vapors (Sax 1984,
p. 1764).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 618)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Manufacturing of pesticides (*Merck 1983); chemical intermediate for
Pharmaceuticals; dimethyl sulfide; fungicides; methionine; in jet fuels; in
preparation of plastics (*SRI); and as a gas odorant to serve as a warning
property for odorless but hazardous gases (*Clayton and Clayton 1981-82).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Do not touch spilled material; stop leak if you can do so
without risk. Shut off ignition sources; no flares, smoking, or flames in
hazard area. Use water spray to reduce vapors. Isolate, area until gas has
dispersed (DOT 1984, Guide 13). Avoid breathing vapors (see Section III
above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 74-93-1
Page 4 of 4
METHYL MERCAPTAN
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 74-93-1
Page 1 of 4
Emergency First Aid Treatment Guide
for
METHYL MERCAPTAN
(74-93-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas, or water-white liquid below 6 degrees C
(43 degrees F) or under pressure.
Odor - Similar to rotten cabbage.
Commercial Form - 98% pure liquefied gas in 180-lb cylinders or tank cars.
Uses - Manufacture of pesticides, fungicides, Pharmaceuticals, methionine,
dimethyl sulfide, plastics, jet fuels, gas odorant for odorless but hazardous
gases.
Materials to Avoid - Mercuric oxide, oxidizers, bleaches.
Caution: Highly flammable. Cylinders may explode when exposed to high
temperatures or fire. Avoid sources of extreme heat or ignition including
sparks or fire. Combustion produces irritating sulfur oxides.
Other Names - Mercaptomethane, methanethiol, methyl sulfhydrate, thiomethanol,
thiomethyl alcohol.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, dopamine, amyl nitrite, sodium nitrite, atropine.
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EFATG
CAS Registry Number: 74-93-1
Page 2 of 4
METHYL MERCAPTAN
Signs and Symptoms of Acute Methyl Mercaptan Exposure:
Warning: Effects may be delayed. Caution is advised.
Signs and symptoms of acute exposure to methyl mercaptan may include fever,
cough, shortness of breath, a feeling of tightness and burning in the chest,
pulmonary edema, respiratory distress, respiratory paralysis, and respiratory
failure/collapse.
Headache, loss of the sense of smell, dizziness, staggering gait, and
heightened emotions may occur. Memory loss, damage to the central and
peripheral nervous systems, tremor, convulsions, and coma may also occur.
Gastrointestinal symptoms include difficulty swallowing, redness of the tongue
and pharynx, nausea, vomiting, abdominal pain, and diarrhea. Urinary
disturbances may also be found. Methyl mercaptan may irritate the eyes and
mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to methyl mercaptan may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methyl mercaptan.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methyl mercaptan.
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EFATG
CAS Registry Number: 74-93-1
Page 3 of 4
METHYL MERCAPTAN
,*
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of methyl mercaptan is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of methyl mercaptan may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
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EFATG
CAS Registry Number: 74-93-1
Page 4 of 4
*
METHYL MERCAPTAN
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 75-15-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CARBON DISULFIDE
CAS Registry Number: 75-15-0
Synonyms: Carbon Bisulfide; Carbon Bisulphide; Carbon Disulphide; Carbon
Sulfide; Dithiocarbonic Anhydride; NCI-C04591; Sulphocarbonic Anhydride;
Sulphuret of Carbon; Weeviltox
Chemical Formula: CS2
Molecular Weight: 76.13
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 116°F, 46.5°C (*Merck 1983)
Specific Gravity (H2O-1): 1.2632 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 360 at 25°C (*Sunshine 1969)
Melting Point: -167°F, -110.8°C (*Weast 1979)
Vapor Density (AIR-1): 2.67 (*Merck 1983)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.294% at 20°C (*Merck 1983)
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CAS Registry Number: 75-15-0
Page 2 of 4
CARBON DISULFIDE
SECTION II (continued)
Appearance and Odor: Mobile clear or faintly yellow liquid; reagent and
commercial grades are foul smelling. Pure distillates have sweet, pleasing
ethereal odor (*Merck 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 20 ppm; Ceiling Concentration 30 ppm; Peak
Concentration 100 ppm/30 minutes/8 hours (*NIOSH 1985)
ACGIH TLV: 30 mg/ms (lOppm) (skin) (*ACGIH 1980)
IDLH: 500 ppm (NIOSH/OSHA 1978, p. 60)
Other Limits Recommended: NIOSH: 10 hour TWA 1 ppm; Ceiling Concentration
10 ppm/15 minutes (NIOSH 1987 p.72); EEGL 50.0 ppm (60 minutes) (NRC 1984a,
pp. 41-56)
Routes of Entry: Inhalation: Yes (*NIOSH/RTECS 1985)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*NIOSH/RTECS 1985)
Health Hazards (Acute, Delayed, and Chronic): The material affects the
central nervous system, cardiovascular system, eyes, kidneys, liver, and
skin. It may be absorbed through the skin as a vapor or liquid, inhaled or
ingested. The probable oral lethal dose for a human is between 0.5 and 5
g/kg or between 1 ounce and 1 pint (or 1 pound) for a 70 kg (150 Ib.)
person (*Gosselin 1976). In chronic exposures, the central nervous system
is damaged and results in the disturbance of vision and sensory changes as
the most common early symptoms (Sax 1984, p. 641). Lowest lethal dose for
humans has been reported at 14 mg/kg or 0.98 grams for a 70 kg person
(*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Alcoholics and those
suffering from neuropsychic trouble are at special risk (*LeFaux 1968).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -22°F, -30°C (CC) (Merck 1983, p. 251)
Flammable Limits:
LEL: 1.3% (*Merck 1983); 1% (*Sunshine 1969)
UEL: 50% (*Merck 1983); 44% (*Sunshine 1969)
Extinguishing Methods: Use dry chemical, carbon dioxide or other inert
gas. Cooling and blanketing with water spray is effective in case of fires
in metal containers or tanks to help prevent reignition by hot surfaces.
Foam is ineffective (NFPA 1984, p. 49-27).
Special Fire Fighting Procedures: If the vapor concentration exceeds 2
percent by volume or is unknown, self-contained breathing mask with.full
face should be used by all persons entering contaminated area ("CHRIS
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CAS Registry Number: 75-15-0
Page 3 of 4
CARBON BISULFIDE
SECTION IV (continued)
1978). Wear special protective clothing. Isolate for 1/2 mile in all
directions if tank car or truck is involved in fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Ignition temperature dangerously low:
212°F, 100°C (Merck 1983, p. 251). Vapors may be ignited by contact with
ordinary light bulb (*NPFA 1978); when heated to decomposition, it emits
highly toxic fumes of oxides of sulfur (*Sax 1979).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (Merck 1983, p. 251)
Stable:
Conditions to Avoid: Decomposes on standing for a long time (Merck
1983, p. 251)
Incompatibility (Materials to Avoid): Air, rust, halogens, metal azides,
metals, oxidants; when exposed to heat or flame reacts violently with
aluminum, chlorine, azides, hypochlorite, ethylamine diamine, ethylene
imine, fluorine, metallic azides of lithium, potassium, cesium, rubidium
and sodium, nitrogen oxides, potassium, zinc and (sulfuric acid plus
permanganate) (Sax 1984, p. 641).
Hazardous Decomposition or Byproducts: When heated to decomposition,
emits highly toxic fumes of sulfur oxides and can react vigorously with
oxidizing materials (Sax 1984, p. 642).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Carbon disulfide is used in the manufacture of soil disinfectants and
vacuum tubes and is used as a solvent for cleaning and extractions,
especially in metal treatment and plating. It is a fumigant for
commodities, a corrosion inhibitor, and a polymerization inhibitor for
vinyl chloride (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of a spill: (1) remove all ignition sources, (2) ventilate area of
spill or leak, and (3) for small quantities, absorb on paper towels.
Evaporate the spills in a safe place, such as a fume hood. Large
quantities can be reclaimed or collected and atomized in a suitable
combustion chamber equipped with an appropriate effluent gas-cleaning
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CAS Registry Number: 75-15-0
Page 4 of 4
CARBON DISULFIDE
SECTION VII (continued)
device (*NIOSH/OSHA 1981). If carbon disulfide is spilled in water,
neutralize with agricultural lime, crushed limestone, or sodium
bicarbonate. If dissolved, apply activated carbon at ten times the spilled
amount. Use mechanical dredges or lifts to remove immobilized masses of
pollutants and precipitates (Student 1981, p. 106). Do not touch spilled
material; stop leak if you can do it without risk. Use water spray to
reduce vapors (DOT 1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/MANY
CPE POOR/MANY
Neoprene POOR/LIMITED*
Nitrile POOR/MANY
PE POOR/MANY
PVC POOR/LIMITED*
Teflon POOR/LIMITED
Viton EXCELLENT/MANY
Viton/Chlorobutyl POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 75-15-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
CARBON BISULFIDE
(75-15-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Clear, colorless, or faintly yellow, mobile liquid.
Odor - Slight, sweetly pleasant, ethereal (commercial form is foul smelling).
Commercial Form - Azeotrope with water containing 97.2% carbon disulfide in
drums or tank cars.
Uses - Solvent, chemical intermediate; polymerization inhibitor; corrosion
inhibitor; agent in metal treatment; anthelmintic; fumigant; manufacture of
soil disinfectants, vacuum tubes, and flotation devices.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire.
Other Names - Carbon bisulfide, carbon sulfide, dithiocarbonic anhydride,
sulphocarbonic anhydride, Weeviltox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, alcohol, water, milk, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbitol, Vitamin B6, urea.
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EFATG
CAS Registry Number: 75-15-0
Page 2 of 3
, CARBON DISULFIDE
Signs and Symptoms of Acute Carbon Disulfide Exposure:
Warning: Effects may be delayed. Caution is advised.
Acute exposure to carbon disulfide primarily affects the central nervous
system producing signs and symptoms that may include headache, dizziness,
difficulty swallowing, nervousness, tremors, mental depression, delirium,
psychosis, convulsions, paralysis, and coma. Nausea, vomiting, cyanosis (blue
tint to skin and mucous membranes), hypothermia (low body temperature), and
peripheral vascular collapse may also occur.
Respiratory effects include coughing, dyspnea (shortness of breath), and
respiratory failure. Carbon disulfide is a strong skin irritant; dermal
exposure may result in severe burns. Eye exposure may cause degeneration of
the retina and optic nerve. Pupils may be dilated.
Emergency Life-Support Procedures:
Acute exposure to carbon disulfide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to carbon disulfide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to carbon disulfide.
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EFATG
' CAS Registry Number: 75-15-0
Page 3 of 3
t
CARBON DISULFIDE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas three times. Wash initially with soap and water
follow with an alcohol wash, then wash again with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: Children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 75-18-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIMETHYL SULFIDE
CAS Registry Number: 75-18-3
Synonyms: 2-Thiapropane; 2-Thiopropane; Dimethyl Monosulfide; Dimethyl
Sulphide; Dimethyl Thioether; DMS, Exact-S; Methane, Thiobis-;
Methanethiomethane; Methyl Monosulfide; Methyl Sulphide; Methylthiomethane;
Thiobismethane
Chemical Formula: C2H6S
Molecular Weight: 62.13
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.031 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 99.7°F, 37.3°C (*Weast 1979)
Specific Gravity (H2O»1): 0.8483 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 400 mmHg at 18.7°C (Perry, 1984, p. 3-55)
Melting Point: -144.9°F, -98.27°C (*Weast 1979)
Vapor Density (AIR=1): 2.14 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor: Colorless liquid with an unpleasant, wild radish,
cabbage-like odor (*Fenaroli 1975).
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CAS Registry Number: 75-18-3
Page 2 of 3
DIMETHYL SULFIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Clayton and Clayton 1981-82)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Dimethyl sulfide causes
softening and irritation of the skin. Orally it is an irritant (*Sax
1975). It is a moderate eye irritant (*Clayton and Clayton 1981-82). It
is an eye, nose, throat and skin irritant (*CHRIS 1978).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -55°F (*Clayton and Clayton 1981-82)
Flammable Limits:
LEL: 2.2% (*Sax 1979)
UEL: 19.7% (*Sax 1979)
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog or foam (*DOT 1984).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing. Move container from fire area. Cool
containers that are exposed to flames with water from the side until well
after the fire is out. For massive fire in cargo area, used unmanned hose
holder or monitor nozzles; if this is impossible withdraw from area and let
fire burn. Withdraw immediately in case of rising sound from venting
safety device or any discoloration of tank due to fire. Isolate for 1/2
mile in all directions if tank car or truck is involved in fire (*DOT
1984).
Unusual Fire and Explosion Hazards: Flammable/combustible material, may
be ignited by heat, sparks or flames. Vapors may travel to a source of
ignition and flash back. Container may explode in heat of fire. Vapor
explosion hazard indoors, outdoors or in sewers (*DOT 1984).
NFPA Flammability Rating: 4
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
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CAS Registry Number: 75-18-3
Page 3 of 3
DIMETHYL SULFIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Reacts vigorously with oxidizing
materials (*Sax 1979). Incompatible with dibenzoyl peroxide (Sax 1984, p.
1201).
Hazardous Decomposition or Byproducts: Combustion products include toxic
and irritating fumes of sulfur dioxide (Weiss 1980, p. 367).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 367)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is a gas odorant, catalyst impregn'ator, solvent for anhydrous mineral
salts, flavoring ingredient in foods and beverages, chemical intermediate
for solvents and dimethyl sulfoxide (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind. Shut off ignition sources; no flares, smoking or flames in
hazard area. Stop leak. Use water spray to reduce vapors. Take up spills
with noncombustible absorbent material (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush eyes with running water for at least 15 minutes. Wash
skin with soap and water. Remove and isolate contaminated clothing and
shoes at the site (*DOT 1984).
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CAS Registry Number: 75-21-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ETHYLENE OXIDE
CAS Registry Number: 75-21-8
Synonyms: alpha, beta-Oxidoethane; Anprolene; Dihydrooxirene; Dimethylene
Oxide; E O; ETO; NCI-C50088; Oxacyclopropane; Oxane; Oxidoethane;
1,2-Epoxyethane; Oxiran; Oxirane; Oxirene, Dihydro-; Oxyfume; Oxyfume 12; T-Gas
Chemical Formula: C2H4O
Molecular Weight: 44.06
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 51.3°F, 10.7°C (*Sunshine 1969)
Specific Gravity (H2O=1): 0.8222 at 10°C/10°C (*Sunshine 1969)
Vapor Pressure (mmHg): 1095 at 20°C (NIOSH/OSHA 1978, p. 100)
Melting Point: -170.5°F.-112.5°C (*Sunshine 1969) '
Vapor Density (AIR=1): 1.49 (*Environment Canada 1982)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Merck 1976)
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CAS Registry Number: 75-21-8
Page 2 of 4
ETHYLENE OXIDE
SECTION II (continued)
Appearance and Odor: Colorless gas at room temperature but a mobile
liquid below 12°C (54°F) and has a sweet odor (*Merck 1976; "CHRIS 1978)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 ppm (NIOSH 1987, p. 122)
ACGIH TLV: 2 mg/m3 (1 ppm) (*ACGIH 1984)
IDLH: 800 ppm (*NIOSH/OSHA 1981)
Other Limits Recommended: NIOSH: <0.1 ppm, 8 hour TWA; 5 ppm, 10 minute
ceiling (NIOSH 1987 p. 122). Industrial substance suspect of carcinogenic
potential for humans - recommended TLV 1 ppm (ACGIH 1984, p. 42).
EEGL 20.0 ppm (60 minutes) (NRC 1986, pp. 35-68).
Routes of Entry: Inhalation: Yes (*Gilman 1980)
Skin: Yes (Sax 1984, p. 1348)
Ingestion: Yes (Sax 1984, p. 1348)
Health Hazards (Acute, Delayed, and Chronic): It can cause death. Lowest
inhalation concentration causing toxic effects is 12500 ppm/10 seconds
(*NIOSH/RTECS 1985). It is a strong skin irritant (*CHRIS 1978). Neuro-
logical disorders and even death have been reported (*Gilman 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Greater than -18°C (*Sunshine 1969); but less
than 0°F (OC) (*CHRIS 1978)
Flammable Limits:
LEL: 3.0% (*Sax 1975)
UEL: 100% (*Sax 1975)
Extinguishing Methods: Extinguish with alcohol foam, carbon dioxide, dry
chemical or water spray, fog, or foam. Let burn unless leak can be stopped
immediately (*DOT 1984).
Special Fire Fighting Procedures: Move container from fire area if you
can do so without risk. Stay away from ends of tanks. Fight fire from
maximum distance. For massive fire in-cargo area, use unmanned hose holder
or monitor nozzles; if this is impossible, withdraw from area and let fire
burn. Withdraw immediately in case of rising sound from venting safety
device or any discoloration of tank due to fire. Isolate for 1 mile in all
directions if tank car or truck is involved in fire. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas. Wear positive pressure breathing apparatus and full protective
clothing. Evacuate area endangered by gas (*DOT 1984).
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CAS Registry Number: 75-21-8
Page 3 of 4
ETHYLENE OXIDE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Severe explosion hazard when exposed
to heat or flame (Sax 1984, p. 1348). Irritating vapors are generated when
heated. Vapor is heavier than air and may travel considerable distance to
a source of ignition and flash back (*CHRIS 1978). Vapor forms explosive
mixtures with air over a wide range (*NFPA 1978). Liquid is not detonable
but the vapor may be readily initiated into explosive decomposition
(*Bretherick 1979).
NFPA Flammability Rating: 4
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Air, heat, acids and bases (Sax 1984,
p. 1348); metal or metal chloride catalysts (*NFPA 1978)
Incompatibility (Materials to Avoid): Metal fittings containing copper,
silver, mercury or magnesium; ammonia (*Bretherick 1979);
oxidizing agents; acids, organic bases; amines; certain salts; alcohols;
mercaptans (*General Electric Co. 1980, MSDS #433); ferric chloride;
magnesium perchlorate; m-nitroaniline; trimethylamine (*ITI 1982);
potassium, tin chlorides; alkanethiols; bromoethane; aluminum
chloride; aluminum oxide; iron chlorides; and iron oxides (Sax 1984, p.
1348).
Hazardous Decomposition or Byproducts: Decomposition products are
explosive (*ITI 1982).
Hazardous Polymerization: May Occur: Yes (*Sax 1975)
May Not Occur:
Conditions to Avoid: Acids; covalent halides such as chlorides of
aluminum, iron (III), tin (IV); basic materials like alkali hydrides,
ammonia, amines, and potassium; catalytically active solids such as
aluminum or iron oxides or rust (*Bretherick 1975); chlorides of boron,
aluminum, tin, and iron; some carbonates; and metals such as copper and
copper alloys (*Patty 1963)
SECTION VI - USE INFORMATION
Ethylene oxide is a chemical intermediate for ethylene glycol, nonionic
surfactants, glycol ethers, ethanolamines, triethylene glycol, and
polyethylene glycol (*SRI). Used as a fumigant for foodstuffs and
textiles, for sterilizing surgical instruments, and as an agricultural
fungicide (Merck 1983, p. 550). Registered as a pesticide in the U.S.
(USEPA/Active Ingredients 1985).
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CAS Registry Number: 75-21-8
Page 4 of 4
ETHYLENE OXIDE
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). Shut off
ignition sources; do not allow flares, smoking or flames in the hazard area.
Stop leak if you can do so without risk. Use water spray to reduce
vapors; do not get water inside container. For small spills flush area
with flooding amounts of water. For large spills dike spill for later
disposal. (*DOT 1984).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED*
CPE GOOD/LIMITED*
Neoprene POOR/LIMITED*
Nitrile POOR/MANY
PVC POOR/LIMITED*
Viton POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 75-21-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
ETHYLENE OXIDE
(75-21-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas; mobile liquid below 12 degrees C (54 degrees F) or
under pressure.
Odor - Sweet, etherlike.
Commercial Forms - Mixtures with carbon dioxide or fluorocarbon 12.
Uses - Chemical intermediate for ethylene glycol, nonionic surfactants, glycol
ethers, ethanolamines, triethylene glycol, polyethylene glycol; fumigant,
fungicide, ripening agent for fruits; sterilizing surgical instruments.
Materials to Avoid - Acids, alcohols, amines, ammonia, oxidizers, metal
catalysts.
Caution: Explosion potential is high. Avoid all heat sources including fire.
Other Names - Anprolene, dihydrooxirene, 1,2-epoxyethane, oxacyclopropane,
oxane, oxidoethane, oxirane, oxyfume.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Ethylene Oxide Exposure:
Warning: Ethylene oxide is corrosive to moist tissues. Caution is advised.
Signs and symptoms of acute exposure to ethylene oxide may be severe, and
include dyspnea (shortness of breath), cough, pulmonary edema, pneumonia, and
respiratory failure. Lethargy, headache, dizziness, twitching, convulsions,
paralysis, and coma may be observed. Cardiac arrhythmias and cardiovascular
collapse may also occur.
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EFATG
CAS Registry Number: 75-21-8
Page 2 of 3
ETHYLENE OXIDE
Gastrointestinal effects of acute exposure may include nausea, vomiting, and
abdominal pain. Ethylene oxide may severely irritate or burn mucous membranes
and moist skin. Eye contact may result in conjunctivitis (red, inflamed eyes)
and erosion of the cornea.
Emergency Life-Support Procedures:
Acute exposure to ethylene oxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to ethylene oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to ethylene oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be IMMEDIATELY flushed with
lukewarm water for AT LEAST 15 minutes.
5. If liquid is spilled on the skin, allow ethylene oxide to vaporize before
washing THOROUGHLY with soap and water.
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EFATG
CAS Registry Number: 75-21-8
Page 3 of 3
ETHYLENE OXIDE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up 1 year old, 125 mL (4 oz or
1/2 cup); children 1 to 12 years old 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Ethylene oxide generally acts as its own cathartic; however, if deemed
necessary, excretion may be promoted by administering a saline cathartic
or sorbitol to conscious and alert victims. Children require 15 to 30 g
(1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is
recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 75-44-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSGENE
CAS Registry Number: 75-44-5
Synonyms: Carbon Oxychloride; Carbonyl Chloride; CG; Chloroformyl Chloride;
NCI-C60219; Carbon Bichloride Oxide; Carbonic Acid Dichloride; Carbonic
Bichloride; Carbonyl Bichloride; Phosgen
Chemical Formula: CC12O
Molecular Weight: 98.92
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 10 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 47°F, 8.2°C (*Merck 1976)
Specific Gravity (H2O=»1): 1.432 at 0°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 1215 at 20°C (*Merck 1976)
Melting Point: -180°F, -118°C (*Merck 1976)
Vapor Density (AIR=1): 3.4 (*NFPA 1975)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (*Merck 1976)
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CAS Registry Number: 75-44-5
Page 2 of 4
PHOSGENE
SECTION II (continued)
Appearance and Odor: Colorless gas; colorless, fuming liquid; suffocating
odor reminiscent of moldy hay (*Merck 1976). In dilute concentration has
odor of green corn (*Arena 1974); odor similar to decaying fruit at room
temperature (*Encyc Occupat Health and Safety 1971).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.4 mg/ms (0.1 ppm) (NIOSH 1987, p. 192).
ACGIH TLV: TWA 0.4 mg/m3 (0.1 ppm) (ACGIH 1986-87, p. 27).
IDLH: 2 ppm (NIOSH 1987, p. 192) \
Other Limits Recommended: NIOSH: 0.1 ppm (10 hour TWA); Ceiling 0.2 ppm for
15 minutes (NIOSH 1987, p. 192). EEGL 0.2 ppm (60 minutes) (NRC 1984b, pp.
69-86).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*DOT 1984)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Phosgene is a lung toxicant
that causes damage to the capillaries, bronchioles and. alveoli of the lungs
(U.S. Army 1975, p. 3-1) by decomposition to hydrochloric acid. There is
little immediate irritant effect upon the respiratory tract, and the
warning properties of the gas are therefore very slight. Pulmonary edema,
bronchopneumonia and occasionally lung abscesses develop. Degenerative
changes in the nerves have been reported as later developments. A
concentration of 25 ppm is dangerous for exposures lasting 30-60 minutes
and 50 ppm is rapidly fatal after even short exposure (Sax 1984, p. 2210).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Nonflammable (NFPA 1984, p. 49-73). For small
fires, use dry chemical or carbon dioxide. Use water spray, fog, or foam
for larger fires. Do not get water inside containers. Move container from
fire area if you can do so without risk. Stay away from the ends of tanks,
and cool exposed containers with water until well after the fire is out.
Isolate the area until gas has dispersed (*DOT 1984).
Special Fire Fighting Procedures: If necessary to stop flow of gas, use
water spray to protect the personnel effecting shutoff. Sodium hydroxide
or anhydrous ammonia have been used to neutralize phosgene (*NFPA 1975).
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CAS Registry Number: 75-44-5
Page 3 of 4
PHOSGENE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition or on
contact with water or steam, it will react to produce toxic and corrosive
fumes (*Sax 1975).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes, in steel containers if dry (U.S. Army 1975,
P. 3-1)
Conditions to Avoid: Moisture (*Sax 1975)
Incompatibility (Materials to Avoid): Reacts violently with aluminum;
tert-butyl azido formate; 2,4-hexadiyn-l,6-diol; isopropyl alcohol;
potassium; sodium; hexafluoro isopropylidene; amino lithium; lithium (Sax
1984, p. 2211).
Hazardous Decomposition or Byproducts: When heated to decomposition or on
contact with water or steam, it will react to produce toxic and corrosive
fumes (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Delayed-action military chemical agent (U.S. Army 1975, p. 3-1). Chemical
intermediate for toluene diisocyanate, methyl isocyanate, acyl chlorides,
diphenylmethane-4,4'-diisocyanate, chloroformate esters, diethyl carbonate,
dimethyl carbamoyl chloride, polymethylene polyphenylisocyanate,
polycarbonate resins (*SRI); aniline dyes (*Hamilton 1974); pesticides,
herbicides, dyes (Hawley 1981, p. 807).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind and keep out of low areas. Ventilate closed spaces before
entering.
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
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CAS Registry Number: 75-44-5
Page 4 of 4
PHOSGENE
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 75-44-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHOSGENE
(75-44-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Easily liquefied colorless gas or colorless to light yellow
liquid.
Odor - Strong and stifling when concentrated, haylike in dilute form.
Commercial Form - 99% pure liquefied gas.
Uses - Organic synthesis; chemical intermediate for isocyanates, acid
chlorides, and polycarbonates; pesticides; herbicides; dye manufacture;
chemical warfare agent.
Materials to Avoid - Active metals, aluminum, alcohol, water (except for use in
emergency life support).
Caution: Hydrochloric acid will be liberated upon contact with water, steam,
or alcohols. A violent reaction will occur following contact with aluminum and
active metals. Phosgene will produce toxic and corrosive fumes when heated to
decomposition; avoid sources of extreme heat.
Other Names - Carbon oxychloride, carbonic acid dichloride, carbonyl chloride,
chloroformyl chloride, diphosgene.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, dimercaprol.
Signs and Symptoms of Acute Phosgene Exposure:
Warning: Effects may be delayed up to 24 hours. Caution is advised.
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EFATG
CAS Registry Number: 75-44-5
Page 2 of 3
PHOSGENE
Acute exposure to phosgene may result in severe irritation and burns of the
skin, eyes, mucous membranes, and respiratory passages. Cough, dyspnea
(shortness of breath), pain in the chest, and severe pulmonary edema may also
occur. Cyanosis (blue tint to the skin and mucous membranes) and anxiety may
be observed.
Emergency Life-Support Procedures:
Acute exposure to phosgene may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosgene.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosgene.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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EFATG
CAS Registry Number: 75-44-5
Page 3 of 3
PHOSGENE
7. RUSH to a health care facility.
Ingestion Exposure: No information is available.
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CAS Registry Number: 75-55-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPYLENEIMINE
CAS Registry Number: 75-55-8
Synonyms: Aziridine, 2-Methyl-; 2-Methylazacyclopropane; 2-Methylaziridine;
2-Methylethylenimine; Methylethylenimine; Propylenimine; Propylene Imine
Chemical Formula: C3H7N
Molecular Weight: 57.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
19 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 1 (pounds) (statutory)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 151-153°F, 66-67°C (*Encyc Occupat Health and Safety 1983)
Specific Gravity (H2O»1): 0.8039-0.8070 at 25°C/25°C (Hawley 1981, p.
865)
Vapor Pressure (mmHg): 112 at 20°C (*IARC 1972-1985)
Melting Point: -85°F, -65°C (*IARC 1972-1985)
Vapor Density (AIR-1): 2.0 (*Encyc Occupat Health and Safety 1983)
Evaporation Rate (Butyl acetate** 1): Not Found
Solubility in Water: Miscible (*IARC 1972-1985)
Appearance and Odor: Colorless, oily liquid with an odor similar to
aliphatic amines (i.e., fishy) (*IARC 1972-1985)
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CAS Registry Number: 75-55-8
Page 2 of 4
PROPYLENEIMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 5 mg/m3 (2 ppm) (NIOSH 1987, p. 200)
ACGIH TLV: TWA 5 mg/ms (2 ppm) (skin) (ACGIH 1986-1987, p. 28)
IDLH: 500 ppm (NIOSH 1987, p. 200)
Other Limits Recommended: Industrial substance suspect of carcinogenic
potential to man (*ACGIH 1983)
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 865)
Skin: Yes (Hawley 1981, p. 865)
Ingestion: Yes (Hawley 1981, p. 865)
Health Hazards (Acute, Delayed, and Chronic): Toxic after acute exposure.
Can severely irritate eyes, skin, and lungs (*Encyc Occupat Health and
Safety 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 25°F (CC) (*ACGIH 1980)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: If material is on fire, use foam, carbon dioxide,
or dry chemical (Student 1981, p. 433).
Special Fire Fighting Procedures: If material is on fire, do not
extinguish fire unless flow can be stopped. Use water in flooding
quantities as a "fog" and use to cool all affected containers. Keep
material out of water sources and sewers. Build dikes to contain flow as
necessary (Student 1981, p. 433). Isolate for 1/2 mile in all directions
if tank car or truck is involved in fire (DOT 1984, Guide 30).
Unusual Fire and Explosion Hazards: Chemical is extremely flammable;
vapors are heavier than air (Student 1981, pp. 433).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Thermally unstable (Student 1981, p. 433)
Stable:
Conditions to Avoid: Not Found
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CAS Registry Number: 75-55-8
Page 3 of 4
PROPYLENEIMINE
SECTION V (continued)
Incompatibility (Materials to Avoid): Acids, strong oxidizers (NIOSH/
OSHA 1978, p. 160)
Hazardous Decomposition or Byproducts: Toxic oxides of nitrogen are
produced during combustion (Student 1981, p. 433).
Hazardous Polymerization: May Occur: Yes (Student 1981, p. 433)
May Not Occur:
Conditions to Avoid: Contact with acid promotes violent
polymerization (Student 1981, p. 433)
SECTION VI - USE INFORMATION
Propyleneimine is used as a chemical intermediate in the modification of
latex surface coating resins, polymers in textile and paper industries,
dyes, photography, gelatins, oil additives and organic synthesis. It is a
comonomer for polymers with methacrylic acid and esters (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors; avoid bodily contact with the material. Do not
handle broken packages without protective equipment. Wash away any
material which may have contacted the body with copious amounts of water or
soap with water. Use water spray to disperse vapors and dilute standing
pools of liquid. Keep sparks and flames away. Attempt to stop leak if it
can be done without hazard. (Student 1981, p. 433).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
'Signs and Symptoms of Exposure: Inflammation and blistering of the skin,
eye and upper respiratory tract; irritation, nausea, itching, and periodic
vomiting. Headache, dizziness, and pain in the temple. Shortness of
breath, and increased nasal and laryngeal secretion are seen (*Encyc
Occupat Health and Safety 1983).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If victim is not breathing, give artificial
respiration; if breathing is labored, give oxygen. In case of eye/skin
contact, immediately flush with water for at least 15 minutes (DOT 1984,
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CAS Registry Number: 75-55-8
Page 4 of 4
PROPYLENEIMINE
SECTION IX (continued)
Guide 30). Neutralization with acids (e.g., vinegar, fruit juices) is
contraindicated. Avoid vomiting (*Rumack 1975 to Present).
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CAS Registry Number: 75-56-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPYLENE OXIDE
CAS Registry Number: 75-56-9
Synonyms: 1,2-Epoxypropane; Epoxypropane; Ethylene Oxide, Methyl-; Methyl
Ethylene Oxide; Methyl Oxirane; Methyloxirane; NCI-C50099; Oxirane, Methyl-;
Propane, 1,2-Epoxy-; Propane, Epoxy; Propene Oxide; Propylene Epoxide;
Propyleneoxide; 1,2-Propylene Oxide
Chemical Formula: C3H6O
Molecular Weight: 58.08
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 93.61°F, 34.23°C (*Merck 1976)
Specific Gravity (H2O=1): 0.859 at 0°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 445 at 20°C (*Sunshine 1969)
Melting Point: -169.83°F, -112.13°C (*Merck 1976)
Vapor Density (AIR=1): 2.0 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 40.5% by weight at 20°C (*Merck 1976)
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CAS Registry Number: 75-56-9
Page 2 of 4
PROPYLENE OXIDE
SECTION II (continued)
Appearance and Odor: Colorless liquid (*Merck 1976) with sweet, alcoholic
odor like natural gas, ether, or benzene (*Clayton and Clayton 1981-82)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 240 mg/m3 (100 ppm) (NIOSH 1987, p. 200)
ACGIH TLV: TWA 50 mg/ms (20 ppm) (*ACGIH 1983)
IDLH: 2000 ppm (NIOSH/OSHA 1978, p. 160)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): This material is
moderately toxic by inhalation and ingestion. It may cause irreversible
and reversible changes (*Sax 1975). Skin contact with the material or
solutions of the material cause irritation; diluted solutions are more
irritating than undiluted materials (*Encyc Occupat Health and Safety
1971). Exposure may cause mild depression of the central nervous system
and eye, nasal, and lung irritation (*Rumack 1975 to Present). Contact
with the liquid can cause blindness and death. Pulmonary edema may recur
up to 2 weeks after exposure (*Morgan 1982).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV — FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -35°F, -37°C (CC) (*Sunshine 1969)
Flammable Limits:
LEL: 2.8% (*Sax 1979)
UEL: 37% (*Sax 1979)
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide, water
spray, fog or foam (DOT 1984, Guide 26).
Special Fire Fighting Procedures: Firefighting should be done from a
safe distance or from a protected location (*NFPA 1978). Wear self-
contained (positive pressure if available) breathing apparatus and full
protective clothing. Isolate for 1/2 mile in all directions if tank car
or truck is involved in fire. Move container from area if you can do so
without risk. Spray cooling water on containers that are exposed to
flames until well after fire is out. For massive fire in cargo area, use
unmanned hose holder or monitor nozzles; if this is impossible, withdraw
from area and let fire burn. Withdraw immediately in case of rising sound
from venting safety device or any discoloration of tank due to fire (DOT
1984, Guide 26).
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CAS Registry Number: 75-56-9
Page 3 of 4
PROPYLENE OXIDE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Vapor is heavier than air and may
travel considerable distance to source of ignition and flash back. Vapors
form explosive mixture with air. If polymerization takes place in
container, there may be a violent rupture of container (*NFPA 1978).
Explosion hazard is severe when exposed to flame (*Sax 1979).
NFPA Flammability Rating: 4
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 787)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Violently reacts with acetylide-
forming metals such as copper or copper alloys (*Clayton and Clayton
1981-82); ammonium hydroxide; chlorosulfonic acid; hydrochloric acid;
hydrofluoric acid; nitric acid; oleum and sulfuric acid (Sax 1984, p.
1289).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Yes (*Clayton and Clayton
1981-82)
May Not Occur:
Conditions to Avoid: Active catalytic surfaces such as anhydrous
chlorides of iron, tin, and aluminum; peroxides of iron and aluminum;
and alkali metal hydroxides (*NFPA 1987); high temperatures; alkalies;
aqueous acids; amines and acidic alcohols (Weiss 1980, p. 787).
SECTION VI - USE INFORMATION
This material is used primarily as a chemical intermediate for
polyurethane polyols, propylene glycol, and dipropylene glycol (*SRI). It
is also used for sterilization of packaged foods (*Farm Chemicals Handbook
1983), as a herbicide (*Clayton and Clayton 1981-82), in the preparation
of lubricants, surfactants, and oil demulcifiers, and as a fumigant and
soil sterilant (*Merck 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill or leak. Do not allow the material to enter
confined space, such as a sewer, because of the possibility of an
explosion (*NIOSH/OSHA 1981). Stop discharge if possible. Stay upwind
and use water spray to knock down vapor. Avoid contact with liquid and
vapor (Weiss 1980, p. 787). Water spray may be used to flush spills
away from exposure and to dilute spills to nonflammable mixture (*NFPA
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CAS Registry Number: 75-56-9
Page 4 of 4
PROPYLENE OXIDE
SECTION VII (continued)
1978). Shut off ignition sources; no flares, smoking, or flames in
hazard area. Stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 26).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Butyl/Neoprene POOR/LIMITED*
Neoprcne POOR/LIMITED*
Nitrile POOR/LIMITED*
PE POOR/MANY
PVC POOR/LIMITED*
Teflon GOOD/LIMITED
Viton POOR/MANY
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 75-56-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
PROPYLENE OXIDE
(75-56-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless liquid or gas above 34 degrees C (94 degrees F).
Odor - Sweet, alcohollike.
Commercial Form - Mixed with carbon dioxide.
Uses - Manufacturer of polyurethane, polyols, propylene glycol, and dipropylene
glycol; fumigant; solvent.
Materials to Avoid - Acids, alkali, oxidizers, metals.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire.
Other Names - Epoxypropane, methyl ethylene oxide, methyl oxirane, propene
oxide, propylene epoxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
aminophylline, morphine, furosemide, epinephrine, atropine.
Signs and Symptoms of Acute Propylene Oxide Exposure:
Propylene oxide may irritate or burn the skin, eyes, and respiratory tract.
Pulmonary edema may occur up to 2 weeks after exposure. Dermatitis (red,
inflamed skin) is common. Other signs and symptoms of acute exposure may
include headache, nausea, vomiting, and unconsciousness. Victims may appear as
if they are in a drunken stupor.
-------
EFATG
CAS Registry Number: 75-56-9
Page 2 of 3
PROPYLENE OXIDE
Emergency Life-Support Procedures:
Acute exposure to propylene oxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to propylene oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to propylene oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 75-56-9
Page 3 of 3
PROPYLENE OXIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 75-74-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TETRAMETHYLLEAD
CAS Registry Number: 75-74-1
Synonyms: Lead Tetramethyl; Methylplumbane; TML; Tetramethyl Lead
Chemical Formula: C4H12Pb
Molecular Weight: 267.33
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Lead Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 230°F, 110°C at 10 mmHg (*IARC 1972-1985); decomposes
above 212°F, 100°C (*NFPA 1975)
Specific Gravity (H2O=1): 1.995 (*Weast 1976)
Vapor Pressure (mmHg): 22 at 20°C (NIOSH/OSHA 1978, p. 176)
Melting Point: -17.5°F, -27.5°C (*Weast 1976)
Vapor Density (AIR-1): 6.5 (NFPA 1984, p. 325M-87)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*IARC 1972-1985)
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CAS Registry Number: 75-74-1
Page 2 of 3
TETRAMETHYLLEAD
SECTION II (continued)
Appearance and Odor: Colorless liquid (*Encyc Occupat Health and Safety
1971); dyed red, orange or blue with a slight musty odor (NIOSH/OSHA 1978,
p. 176).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.075 mg (Lead)/m3 (OSHA 1984, p. 663)
ACGIH TLV: TWA 0.15 mg (Lead)/m3 (skin) (ACGIH 1986-87, p.30)
IDLH: 40 mg(Lead)/m3 (NIOSH 1987, p. 222)
Other Limits Recommended: Maximum air concentration: 0.15 mg/m3 (skin)
(*Casarett 1975)
Routes of Entry: Inhalation: Yes (*NFPA 1975)
Skin: Yes (*NFPA 1975)
Ingestion: Yes (*NFPA 1975)
Health Hazards (Acute, Delayed, and Chronic): Vapors are very toxic.
Fatal lead poisoning may occur by ingestion, vapor inhalation or skin
absorption (*NFPA 1975). Several cases of acute toxicity, usually in the
form of degenerative brain disease, have been described following
occupational exposure (*IARC 1972-1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 38°C (*IARC 1972-1985)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: On fires in which containers are not exposed, use
water spray, dry chemical, foam or carbon dioxide (*NFPA 1975).
Special Fire Fighting Procedures: Use water to keep fire exposed
containers cool. If leak or spill has not ignited, use water spray to
disperse vapors or flush spill (*NFPA 1975). For massive fire in cargo
area, use unmanned hose holder or monitor nozzle; if this is impossible
withdraw from area and let fire burn (*DOT 1984).
Unusual Fire and Explosion Hazards: Thermal decomposition is likely to
take the form of vapors at the surface. Rapid decomposition will cause
container to explode (*NFPA 1975). Dangerous fire hazard when exposed to
heat, flame, or oxidizers (Sax 1984, p. 2546).
NFPA Flammability Rating: 3
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CAS Registry Number: 75-74-1
Page 3 of 3
TETRAMETHYLLEAD
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 865)
Conditions to Avoid: Fire, heat, physical damage, and strong
oxidizers (*NFPA 1975). Starts to decompose at about 212°F (100°C).
If confined, may explode or detonate at high temperatures (Weiss 1980,
p. 865).
Incompatibility (Materials to Avoid): Strong oxidizers such as sulfuryl
chloride or potassium permanganate (NIOSH/OSHA 1978, p. 176).
Hazardous Decomposition or Byproducts: Toxic gases are generated in fire
(Weiss 1980, p. 865).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 865)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Antiknock additive for gasolines; component of mixed alkyl leads for
gasoline additives (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other non-combustible absorbent material and place into containers for
later disposal. Large spills: dike far ahead of spill for later disposal
(*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 75-74-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
TETRAMETHYLLEAD
(75-74-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Musty or fruity.
Commercial Form - Red, orange, or blue liquid.
Use - Gasoline additive.
Materials to Avoid - Oxidizers.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. When burned, toxic fumes of lead oxide will be
emitted.
Other Names - Tetramethylplumbane, TML.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbitol, mannitol, dexamethasone.
Signs and Symptoms of Acute Tetramethyllead Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and symptoms of acute exposure to tetramethyllead may be severe and
include anxiety, irritability, headache, insomnia, disorientation,
violent/frightening dreams, hyperexcitability, delusions, and hallucinations.
Muscular weakness, tremor, incoordination, convulsions, cerebral edema, and
coma may occur. A metallic taste may be noted. Sneezing, bronchitis, and
pneumonia may be noted. Bradycardia (slow heart rate), hypotension (low blood
-------
EFATG
CAS Registry Number: 75-74-1
Page 2 of 3
TETRAMETHYLLEAD-
pressure), hypothermia, and pallor may also occur. Gastrointestinal symptoms
include vomiting and diarrhea. Tetramethyllead may irritate moist skin, eyes,
and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to tetramethyllead may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to tetramethyllead.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to tetramethyllead.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 75-74-1
Page 3 of 3
TETRAMETHYLLEAD
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: Children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50. to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 75-77-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TRIMETHYLCHLOROSILANE
CAS Registry Number: 75-77-4
Synonyms: Chlorotrimethylsilane; Monochlorotrimethylsilicon; Silane,
Chlorotrimethyl-; Silane, Trimethylchloro-; Silicane, Chlorotrimethyl;
Silylium, Trimethyl-, Chloride; Trimethyl Chlorosilane; Trimethylsilyl Chloride
Chemical Formula: C3H9ClSi
Molecular Weight: 108.66
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCiow inhalation
(mouse) 0.5 mg/liter/10 minute (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 135°F, 57°C (*Hawley 1977)
Specific Gravity (H2O-1): 0.854 at 25°C (*Hawley 1977)
Vapor Pressure (mmHg): Not Found
Melting Point: -72°F, -57.7°C (*Weast 1984)
Vapor Density (AIR=1): 3.7 (*CHRIS 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (*Hawley 1977)
Appearance and Odor: Colorless liquid (*Hawley 1977), with a sharp
hydrochloric acid-like odor (*CHRIS 1978).
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CAS Registry Number: 75-77-4
Page 2 of 3
TRIMETHYLCHLOROSILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Hawley 1977; *Rumack 1975 to Present)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Similar to other silanes.
Toxicity is rated high for inhalation, ingestion and local irritation. May
cause death or permanent injury after a very short exposure to small
quantities (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -18°F (*Hawley 1977); 0°F (OC) (*CHRIS 1978)
Flammable Limits:
LEL: 1.8% (*CHRIS 1978)
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemicals or carbon dioxide.
Do not use water or foam. Cool exposed containers with water (*CHRIS
1978). Water spray, fog, or foam may be required to fight large fires.
However, trimethylchlorosilane may react violently with water. Do not get
water inside containers (*DOT 1984).
Special Fire Fighting Procedures: Use acid-vapor-type respirator, rubber
gloves, chemical worker's goggles, and other protective equipment as
necessary to protect skin and eyes ("CHRIS 1978).
Unusual Fire and Explosion Hazards: Violent reaction with water (Sax
1984, p. 2665). Toxic and irritating hydrogen chloride and phosgene may be
formed in fires. Difficult to extinguish, re-ignition may occur.
Flashback along vapor trail may occur. Containers may explode in fire.
Vapor may explode if ignited in enclosed area (CHRIS 1987).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 895, *CHRIS 1978)
Conditions to Avoid: Avoid contact with water; it readily hydrolyzes,
liberating hydrochloric acid ("Hawley 1977).
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CAS Registry Number: 75-77-4
Page 3 of 3
TRIMETHYLCHLOROSILANE
SECTION V (continued)
Incompatibility (Materials to Avoid): Reacts with surface moisture,
releasing hydrogen chloride, which will corrode common metals and form
flammable hydrogen gas ("CHRIS 1978).
Hazardous Decomposition or Byproducts: When heated to decomposition or on
contact with acids or acid fumes, chloride fumes are emitted (*Sax 1979).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 895)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chemical intermediate for silicone fluids, silylating agent, and a component
of a catalyst for propylene oxide (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). In case of spill or leak,
shut off ignition sources; no flares, smoking or flames in hazard area. Do
not touch spilled material. Stop leak if you can do it without risk. Do
not get water inside container. For small spills, take up with sand or
other non-combustible absorbent material and place into container for later
disposal. For large spills, dike far ahead of spill for later disposal
(*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number 75-77-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
TRIMETHYLCHLOROSILANE
(75-77-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, acrid.
Commercial Form - 98% pure liquid.
Uses - Catalyst, solvent, silylating agent, manufacture of silicone fluids.
Material to Avoid - Water (except for use in emergency life support).
Caution: Highly flammable. Avoid sources of extreme heat or ignition
including sparks or fire.
Other Names - Chlorotrimethylsilane, trimethylsilyl chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Trimethylchlorosilane Exposure:
Warning: In the presence of water, trimethylchlorosilane liberates
hydrochloric acid, which is extremely corrosive. Caution is advised.
Signs and symptoms of acute trimethylchlorosilane exposure may include
increased salivation, intense thirst, difficulty swallowing, chills, pain, and
shock. Oral, esophageal, and stomach burns are common. Vomitus generally has
a coffee-ground appearance.
-------
EFATG
CAS Registry Number: 75-77-4
Page 2 of 3
TRIMETHYLCHLOROSILANE
Acute inhalation exposure may result in hoarseness, laryngitis, a feeling of
suffocation, dyspnea (shortness of breath), choking, respiratory tract
irritation, chest pain, and pulmonary edema. The potential for circulatory
collapse is high following ingestion of trimethylchlorosilane. Sneezing,
bleeding of the nose and gums, and ulceration of the nasal and oral mucosa may
also occur. Renal toxicity has been observed in animals.
If the eyes come in contact with trimethylchlorosilane, irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure is
generally followed by dermatitis (red, inflamed skin), severe burns, pain, and
shock.
Emergency Life-Support Procedures:
Acute exposure to trimethylchlorosilane may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to trimethylchlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to trimethylchlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
-------
EFATG
CAS Registry Number: 75-77-4
Page 3 of 3
TRIMETHYLCHLOROSILANE
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Inform victims not to swallow
this water.
3. DO NOT induce vomiting or attempt to neutralize!
4 Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: Children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
-------
CAS Registry Number: 75-78-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIMETHYLDICHLOROSILANE
CAS Registry Number: 75-78-5
Synonyms: Dichlorodimethylsilane; Dichlorodimethylsilicon; Inerton AW-DMCS;
Silane, Dichlorodimethyl-
Chemical Formula: C2H6Cl2Si
Molecular Weight: 129.07
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation:
(mouse) 0.0003 mg/liter/2 hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 158°F, 70°C (NFPA 1984, p. 325M-42)
Specific Gravity (H2O=1): 1.1 (NFPA 1984, p. 325M-42)
Vapor Pressure (mmHg): 100 at 17.5°C (Weast 1984, p. D-200)
Melting Point: -123°F, -86°C (*CHRIS 1978)
Vapor Density (AIR=1): 4.45 (NFPA 1984, p. 352M-42)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (NFPA 1984, p. 325M-42)
Appearance and Odor: Colorless liquid with sharp irritating odor (*CHRIS
1978).
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CAS Registry Number: 75-78-5
Page 2 of 4
DIMETHYLDICHLOROSILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*CHRIS 1978)
Skin: Yes (*CHRIS 1978)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Inhalation irritates mucous
membranes. Severe gastrointestinal damage may occur. Vapors cause severe
eye and lung injury. Upon short contact, second and third degree burns may
occur (*CHRIS 1978).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 16°F (OC) (*Hawley 1977)
Flammable Limits:
LEL: 3.4% (*Sax 1975)
UEL: 9.5% (*Sax 1975)
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam. Move container from fire area if it can be done
without risk. Do not get water inside container. Cool containers that are
exposed to fire from outside until well after fire is out. Withdraw
immediately in case of rising sound from venting safety device or
discoloration of tank due to fire (DOT 1984, Guide 29).
Special Fire Fighting Procedures: Avoid contact with skin, eyes, or
clothing. Wear acid-vapor respirator, rubber gloves, chemical worker's
goggles, other protective and corrosive-resistant equipment as needed
(*CHRIS 1978; *Encyc Occupat Health and Safety 1971). Runoff from fire
control or dilution water may cause pollution. Isolate for one-half mile
in all directions if tank car or truck involved in fire (DOT 1984, Guide
29).
Unusual Fire and Explosion Hazards: Vapor may explode if ignited in an
enclosed area; reacts with water to produce irritating and toxic gases.
Toxic and irritating hydrogen chloride and phosgene may form in fire
(CHRIS 1987). Runoff to sewer may create fire or explosion hazard (DOT
1984, Guide 29).
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980)
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CAS Registry Number: 75-78-5
Page 3 of 4
DIMETHYLDICHLOROSILANE
SECTION V - REACTIVITY DATA (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Reacts vigorously with water to
generate hydrogen chloride ("CHRIS 1978).
Hazardous Decomposition or Byproducts: Reacts with water; irritating gas
is produced. Hydrogen chloride and phosgene gases may be formed upon
heating (CHRIS 1987).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chemical intermediate for silicone fluids and in ethchlorvynol assays
(*SRI; *AOAC 1965).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). Shut off
ignition sources; no flares, smoking or flames in hazard area. Do not
touch spilled materials; stop leak if you can do so without risk. Use
water spray to reduce vapors; however do not get water inside containers.
Small spills: absorb with sand or other non-combustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 29). Use effective fume
removal device (*AOAC 1965).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene GOOD/LIMITED**
Nitrile POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 75-78-5
Page 4 of 4
DIMETHYLDICHLOROSILANE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 75-78-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIMETHYLDICHLOROSILANE
(75-78-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, irritating.
Commercial Form - Liquid in steel drums.
Use - Manufacture of silicone products.
Material to Avoid - Water (except for use in emergency life support).
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. Dimethylchlorosilane will liberate hydrochloric acid
upon contact with water.
Other Names - Dichlorodimethylsilane, dichlorodimethylsilicon, Inerton AW-DMCS.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Dimethyldichlorosilane Exposure:
Signs and symptoms of acute ingestion of dimethyldichlorosilane may be severe
and include increased salivation, intense thirst, difficulty swallowing,
chills, pain, and shock. Oral, esophageal, and stomach burns are common.
Vomitus generally has a coffee-ground appearance. The potential for
circulatory collapse is high following ingestion of dimethyldichlorosilane.
-------
EFATG
CAS Registry Number: 75-78-5
Page 2 of 3
DIMETHYLDICHL.OROSILANE
Acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea
(shortness of breath), respiratory tract irritation, and chest pain. Bleeding
of nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema,
chronic bronchitis, and pneumonia may also occur.
If the eyes have come in contact with dimethyldichlorosilane, irritation,
pain, swelling, corneal erosion, and blindness may result Dermatitis (red,
inflamed skin), severe bu.rns, pain, and shock generally follow dermal exposure.
Emergency Life-Support Procedures:
Acute exposure to dimethyldichlorosilane may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dimethyldichlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dimethyldichlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
-------
EFATG
CAS Registry Number: 75-78-5
Page 3 of 3
DIMETHYLDICHLOROSILANE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Rinse mouth with large amounts of water. Inform victims not to swallow
this water.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: Children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
-------
CAS Registry Number: 75-79-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYLTRICHLOROSILANE
CAS Registry Number: 75-79-6
Synonyms: Methylsilyl Trichloride; Silane, Methyltrichloro-; Silane,
Trichloromethyl-; Trichloromethylsilane; Trichloromethylsilicon
Chemical Formula: CH3Cl3Si
Molecular Weight: 149.48
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.00018 mg/liter/2 hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 152°F, 66.5°C (*Clayton and Clayton 1981-82)
Specific Gravity (H2O=1): 1.27 at 25°C (*CHRIS 1978)
Vapor Pressure (mmHg): Not Found
Melting Point: -108°F, -77.8°C (Weast 1983, p. C-515)
Vapor Density fAIR=l): 5.17 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Acrid odor, sharp like hydrochloric acid, colorless
liquid (*CHRIS 1978).
-------
CAS Registry Number: 75-79-6
Page 2 of 3
METHYLTRICHLOROSILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): As with other
chlorosilanes, acute exposures may be highly toxic and may cause death or
permanent injury after very short exposures to small quantitites. Chronic
exposures may be moderately toxic and involve irreversible and reversible
changes (*Sax 1975). Skin contact may produce severe burns with pain and
risk of secondary infections. Ingestion may produce oral, esophageal, and
stomach burns, intensity will vary from mild to very severe,
gastrointestinal damage is rare but may occur (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 45°F (OC); 15°F (CC) (*CHRIS 1978)
Flammable Limits:
LEL: 7.6% (*NFPA 1978)
UEL: 20% (*NFPA 1978)
Extinguishing Methods: Dry chemical or carbon dioxide may be used for
small fires. Water may be used for large fires if firefighters are
protected from violent reaction of methyltrichlorosilane with water. Water
may be used to keep containers cool (*NFPA 1978).
Special Fire Fighting Procedures: Self-contained breathing apparatus is
required as combustion/decomposition yields acid gases/pulmonary irritants.*
Corrosion-resistant protective clothing, as well as appropriate foot,
hand, arm, head, eye, and face protection are required where contact is
possible (*Encyc Occupat Health and Safety 1971).
Unusual Fire and Explosion Hazards: Toxic hydrogen chloride and phosgene
gases may form in fires. Reacts with water to form hydrochloric acid
(CHRIS 1987). Vapor forms flammable mixture with air (*NFPA 1978). May
form explosive mixture in air (*Hawley 1977).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Hawley 1977; 'CHRIS 1978)
Stable:
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CAS Registry Number: 75-79-6
Page 3 of 3
METHYLTRICHLOROSILANE
SECTION V - REACTIVITY DATA (continued)
Conditions to Avoid: Contact with water or moist air (*NFPA 1978,
*Sax 1979).
Incompatibility (Materials to Avoid): Reacts with water or steam to form
hydrochloric acid ("CHRIS 1978).
Hazardous Decomposition or Byproducts: Hydrogen chloride and phosgene
formed in fires (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Monomer for silicone resins (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Spills can be neutralized by flushing with large quantities of water
followed by treatment with sodium bicarbonate. Provide adequate protection
against generated hydrogen chloride. Do not allow water to get into
container since resulting pressure could cause container to rupture (*NFPA
1978). Protect against potentially violent reaction with water (see
Section III above). Avoid breathing vapors and contact with skin
(see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 75-79-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHYLTRICHLOROSILANE
(75-79-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, acrid.
Commercial Form - Liquid in 55-gallon drums or 1-gallon glass bottles.
Use - Manufacture of silicones.
Material to Avoid - Water (except for use in emergency life support).
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire.
Other Names - Methylsilyltrichloride, trichloromethylsilane,
trichloromethylsilicon.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Methyltrichlorosilane Exposure:
Warning: In the presence of water, methyltrichlorosilane liberates
hydrochloric acid, which is extremely corrosive. Caution is advised.
Signs and symptoms of acute ingestion of methyltrichlorosilane may include
excessive salivation, intense thirst, difficulty in swallowing, chills, pain,
and shock. Oral, esophageal, and stomach burns are common. Vomitus generally
has a coffee-ground appearance. The potential for circulatory collapse is high
following ingestion of methyltrichlorosilane.
-------
EFATG
CAS Registry Number: 75-79-6
Page 2 of 3
METHYLTRICHLOROSILANE
Acute inhalation exposure may result in hoarseness, laryngitis, a feeling of
suffocation, dyspnea (shortness of breath), choking, respiratory tract
irritation, chest pain, and pulmonary edema. Sneezing, bleeding of the nose
and gums, and ulceration of the nasal and oral mucosa may also occur. Renal
toxicity has been observed in animals.
If the eyes have come in contact with methyltrichlorosilane, then irritation,
pain, swelling, corneal erosion, and blindness may result Dermatitis (red,
inflamed skin), severe burns, pain, and shock generally follow dermal exposure.
Emergency Life-Support Procedures:
Acute exposure to methyltrichlorosilane may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methyltrichlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methyltrichlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
r
5. Wash exposed skin areas THOROUGHLY with soap and water.
-------
EFATG
CAS Registry Number: 75-79-6
Page 3 of 3
METHYLTRICHLOROSILANE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Inform victims not to swallow
this water.
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
-------
CAS Registry Number: 75-86-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ACETONE CYANOHYDRIN
CAS Registry Number: 75-86-5
Synonyms: 2-Cyano-2-Propanol; 2-Hydroxy-2-Methylpropionitrile;
2-Hydroxyisobutyronitrile; 2-Methyllactonitrile; 2-Propanone, Cyanohydrin;
alpha-Hydroxyisobutyronitrile; Lactonitrile, 2-Methyl-; Propanenitrile,
2-Hydroxy-2-Methyl-; USAF RH-8
Chemical Formula: C4H7NO
Molecular Weight: 85.10
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(Guinea Pig) 9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 180°F, 82°C at 23 mmHg (Weast 1983, p. C-209)
Specific Gravity (H2O=1): 0.9267 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 0.8 at 20°C (*Clayton and Clayton 1981-82)
Melting Point: -2.2°F, -19°C (*Merck 1976)
Vapor Density (AIR-1): 2.93 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble in water (*Merck 1976)
Appearance and Odon Colorless liquid (*Hawley 1977); distinct strong
cyanide odor (*Lefaux 1968)
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CAS Registry Number: 75-86-5
Page 2 of 4
ACETONE CYANOHYDRIN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Patty 1963)
Skin: Yes (*Patty 1963)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): This material is considered
very hazardous and should only be handled under conditions that prevent any
inhalation of vapor or skin contact (*Patty 1963). May be slightly
irritating to skin and mucous membranes (*Merck 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 165°F, 74°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 2.2% (*NFPA 1978)
UEL: 12% (*NFPA 1978)
Extinguishing Methods: Water may cause frothing if it gets below surface
of liquid and turns to steam. Water fog gently applied to surface will
cause frothing which will extinguish fire. Use water spray, dry chemical,
alcohol foam, or carbon dioxide. Use water to keep fire-exposed containers
cool, from a safe distance (*NFPA 1978).
Special Fire Fighting Procedures: Wear air-supplied mask with canister
approved for use with acrylonitrile in less than 2 percent concentration,
rubber or plastic gloves, cover goggles or face mask, rubber boots, slicker
suit, safety helmet (*CHRIS 1978).
Unusual Fire and Explosion Hazards: Too dangerous to health to expose
fire fighters; a few whiffs of vapor could cause death; vapor or liquid
could be fatal on penetrating normal protective clothing. Vapor forms
explosive mixture with air (*NFPA 1978). On contact with sulfuric acid, it
may explode (*Sax 1979).
NFPA Flammability Rating: 1
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
-------
CAS Registry Number: 75-86-5
Page 3 of 4
ACETONE CYANOHYDRIN
SECTION V (continued)
Conditions to Avoid: Vapor forms explosive mixtures with air (*NFPA
1978)
Incompatibility (Materials to Avoid): May react violently with water
(*NFPA 1978). Contact with sulfuric acid may cause it to explode (*Sax
1979).
Hazardous Decomposition or Byproducts: Decomposes when heated to 248°F or
at lower temperature under alkaline conditions, emitting highly toxic
hydrogen cyanide (*NFPA 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacture of insecticides (*Hawley 1977) and as a chemical
intermediate (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Use water spray to reduce vapors. Small
spills: take up with sand or other noncombustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55). Prevent any inhalation
of vapor or skin contact (*Patty 1963).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea, loss of consciousness,
convulsions (*Clayton and Clayton 1982); irregular heart beat, headache,
vomiting (*Patty 1963). Slightly irritating to the skin (*Merck 1976).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration
(avoid mouth to mouth resuscitation). If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
-------
CAS Registry Number: 75-86-5
Page 4 of 4
ACETONE CYANOHYDRIN
SECTION IX (continued)
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation. Avoid
contact with contaminated skin (DOT 1984, Guide 55; *Rumack 1975 to
Present).
-------
CAS Registry Number: 76-02-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ TRICHLOROACETYL CHLORIDE
CAS Registry Number: 76-02-8
Synonyms: (NIOSH/RTECS 1985 Synonyms On-Line File) Acetyl Chloride,
Trichloro-; Trichloroacetic Acid Chloride; Trichloroacetochloride
Chemical Formula: CC13COC1
Molecular Weight: 181.83
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC50 inhalation (mouse) 0.445 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 244°F, 118°C (Hawley 1981, p. 1040)
Specific Gravity (H2O=1): 1.654 at 0°C/4°C (Hawley 1981, p. 1040)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Weast 1979, p. C-98)
Appearance and Odor: Liquid (Hawley 1981, p. 1040)
-------
CAS Registry Number: 76-02-8
Page 2 of 4
TRICHLOROACETYL CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIHTLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 1040)
Skin: Yes (Hawley 1981, p. 1040)
Ingestion: Yes (Hawley 1981, p. 1040)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by ingestion
and inhalation; strong Irritant to skin and tissues (Hawley 1981, p. 1040).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Material may react violently with water.
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 59).
Special Fire Fighting Procedures: Move container from fire area if you
can do so without risk. Spray cooling water on containers that are exposed
to flames until well after fire is out. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Wear positive pressure breathing apparatus and special protective clothing
(DOT 1984, Guide 59).
Unusual Fire and Explosion Hazards: Material may burn but does not ignite
readily. Poisonous if inhaled or swallowed; skin contact poisonous.
Contact may cause burns to skin and eyes (DOT 1984, Guide 59).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 76-02-8
Page 3 of 4
TRICHLOROACETYL CHLORIDE
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas (DOT 1984, Guide 59).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Contact may cause burns to skin and eyes
(DOT 1984, Guide 59).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Remove and isolate contaminated clothing and shoes at the site. Keep
victim quiet and maintain normal body temperature. Effects may be delayed;
keep victim under observation (DOT 1984, Guide 59).
-------
CAS Registry Number: 76-02-8
Page 4 of 4
TRICHLOROACETYL CHLORIDE
COMMENTS
Sources searched but no information found:
NIOSH/RTECS 1983
ACGIH 1983
NIOSH/OSHA 1978
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Oilman 1985
-------
CAS Registry Number: 77-47-4
Page 1 of 4
EPA' CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - HEXACHLOROCYCLOPENTADIENE
CAS Registry Number: 77-47-4
Synonyms: 1,3-Cyclopentadiene, 1,2,3,4,5,5-Hexachloro-; C 56; Graphlox;
HCCPD; Hexachlorocyclopentadien; Hexachloropentadiene; HRS 1655; NCI-C55607;
PCL; Perchlorocyclopentadiene
Chemical Formula: CSC16
Molecular Weight: 272.77
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC50 inhalation (rat) 0.018 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds) (statutory); 100 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 462°F, 239°C at 753 mmHg (*Weast 1984)
Specific Gravity (H2O=1): 1.7019 at 25°C/4°C (*Weast 1984)
Vapor Pressure (mmHg): 0.080 at 25°C (*Clayton and Clayton 1981-82)
Melting Point: 16°F, -9°C (*Weast 1984)
Vapor Density (AIR=1): 9.4 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 800 ppb (*Clayton and Clayton 1981-82)
Appearance and Odor: Yellow-green liquid (*Weast 1984) with a pungent
odor (*Hawley 1981)
-------
CAS Registry Number: 77-47-4
Page 2 of 4
HEXACHLOROCYCLOPENTADIENE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/ms (0.01 ppm) (ACGIH 1986-87, p.20)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1981)
Skin: Yes (*Hawley 1981)
Ingestion: Yes (*Hawley 1981)
Health Hazards (Acute, Delayed, and Chronic): This compound is very toxic
and may be fatal if inhaled, swallowed, or absorbed through the skin. The
probable human lethal dose is 50-500 mg/kg, or between 1 teaspoon and 1
ounce for a 150 Ib. (70 kg) person. Severe exposure induces pulmonary
hyperemia and edema, degenerative and necrotic changes in brain, heart and
adrenal glands and necrosis of liver and kidney tubules (*DOT 1984;
Gosselin 1984, p. 11-169).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Non-flammable (*Hawley 1981)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray or
foam for small fires. For large fires, use water spray, fog, or foam.
Move hexachlorocyclopentadiene from fire area if this can be done without
risk (*DOT 1984).
Special Fire Fighting Procedures: Isolate hazard area and deny entry.
Wear positive pressure breathing apparatus and special protective clothing.
Fight fire from maximum distance. Dike fire control water for later
disposal (*DOT 1984).
Unusual Fire and Explosion Hazards: Toxic hydrogen chloride, chlorine,
and phosgene gases may form in fires. In presence of moisture, will
corrode iron and other materials; flammable and explosive hydrogen gas may
collect in enclosed space (Weiss 1980, p. 498).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 77-47-4
Page 3 of 4
HEXACHLOROCYCLOPENTADIENE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Reacts slowly with water to form hydrochloric
acid; however, the reaction is not hazardous (Weiss 1980, p. 498).
Incompatibility (Materials to Avoid): Will corrode iron and other metals
in the presence of moisture (Weiss 1980, p. 498).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 498)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Major uses of hexachlorocyclopentadiene include applications as a chemical
intermediate for insecticides and flame retardants (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard and deny entry. Stay upwind
and keep out of low areas. Ventilate closed spaces before entering. Do
not touch spilled material; stop leak if this can be done without risk.
Use water spray to reduce vapors. Absorb small spills with sand or other
noncombustible absorbent material and place into containers for later
disposal. Dike far ahead of large spills for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Nitrile POOR/LIMITED
Viton GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 77-47-4
Page 4 of 4
HEXACHLOROCYCLOPENTADIENE
*
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation of mist is highly irritating
to mucous membranes, causing tearing, sneezing, and salivation. Eye
contact may result in severe irritation. Contact of liquid with the skin
may cause blistering and burning (*CHRIS 1978). Headaches and throat
irritation have also been reported as a result of exposure to this compound
(Clayton and Clayton 1981, p. 3751).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with the material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from the skin is of extreme importance. Keep
victim quiet and maintain normal body temperature. Since effects may be
delayed, keep victim under observation (*DOT 1984).
-------
CAS Registry Number: 77-78-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIMETHYL SULFATE
CAS Registry Number: 77-78-1
Synonyms: Dimethyl Monosulfate; Dimethyl Sulphate; DMS; DMS (Methyl Sulfate);
Methyl Sulfate; Sulfuric Acid, Dimethyl Ester; Dimethylsulfate
Chemical Formula: C2H6O4S
Molecular Weight: 126.14
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC50 inhalation (mouse) 0.28 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory); 100 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: About 370°F, 188°C (with decomposition) (*Merck 1983)
Specific Gravity (H2O=1): 1.3283 at 20°C (*Weast 1979)
Vapor Pressure (mmHg): 0.1 at room temperature (*IARC 1972-1985); 0.5 at
20°C (NIOSH/OSHA 1978, p. 90)
Melting Point: -25.15°F, -31.75°C (*Weast 1979)
Vapor Density (AIR=1): 4.35 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 2.8 g/100 mL at 18°C (*Merck 1983)
Appearance and Odor: It is a colorless oily liquid (*Merck 1983) with a
faint, onion-like odor (*NFPA 1978)
-------
CAS Registry Number: 77-78-1
Page 2 of 4
DIMETHYL SULFATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 mg/ms (1 ppm) (NIOSH 1987, p. 110)
ACGIH TLV: TWA 0.5 mg/m3 (0.1 ppm) (skin) (ACGIH 1985, p. 17)
IDLH: 10 ppm (NIOSH/OSHA 1978, p. 90)
Other Limits Recommended: Industrial substance suspect of carcinogenic
potential for man (ACGIH 1985, p. 42).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Acute: extremely toxic
vapors and liquid — a few whiffs or contact on skin could be fatal (*NFPA
1978). Also acutely toxic if ingested. Delayed effects which are
ultimately fatal may also occur (*Merck 1983). Lethal concentrations as
low as 97 ppm/10 min have been reported in humans. DNA inhibition and
damage to human somatic cells, and sister chromatid exchange in human
fibroblast cells were observed (*NIOSH/RTECS 1985). Delayed appearance of
symptoms may permit unnoticed exposure to lethal quantities (Merck 1983, p.
475).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 182°F (CC) (*Hawley 1977)
Flammable Limits: Moderate fire potential when exposed to heat or flame
(*Sax 1975)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: To extinguish small fires use water, foam, carbon
dioxide, and dry chemicals (*Sax 1975). For large fires use water spray,
fog, or foam. Move container from fire area if you can do it without risk.
Cool containers exposed to flames with water. Fight fire from a maximum
distance (DOT 1984, Guide 57).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Dike fire control water for
later disposal. Do not scatter material (DOT 1984, Guide 57).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: 2
-------
CAS Registry Number: 77-78-1
Page 3 of 4
DIMETHYL SULFATE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*IARC 1972-1985)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Material is normally stable even
under fire exposure conditions and is not hazardously reactive with water
(*NFPA 1978). It is incompatible with strong oxidizers and strong ammonia
solutions (NIOSH/OSHA 1978, p. 90).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used as a chemical intermediate for quaternary ammonium salts and for
alkylation of phenols and thiols ("'SRI), and as a methylating agent in the
manufacture of many organic chemicals (*Merck 1983). Formerly, dimethyl
sulfate was used as a war gas. It is also used in the manufacture of dyes,
perfumes, for the separation of mineral oils, and for the analysis of auto
fluids (*Browning 1965).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
If spilled in a building, the building must be evacuated and the agent
decomposed by hosing with water or spraying with 5 percent sodium hydroxide
(caustic soda) (*Dreisbach 1977). For large spills, evaporating
vapors can be collected in a chamber with a gas cleaning device
(*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Immediate effects of vapor exposure are
eye irritation, cough, swelling of tongue, lips, and larynx, and lungs
-------
CAS Registry Number: 77-78-1
Page 4 of 4
DIMETHYL SULFATE
SECTION IX (continued)
(later). Ingestion or direct contact with mucous membranes causes
corrosion. Once absorbed, lung damage and liver and kidney injury will
occur (*Dreisbach 1977). Liquid dermal exposure causes blistering,
followed by convulsions, delirium, coma, and death in severe cases (*Merck
1983).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If not breathing, start artificial respiration; if
breathing is difficult, give oxygen. If dermal contact occurs, immediately
flush with water for 15 minutes. It is very important to quickly remove
material from skin. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Since
effects may be delayed, keep a close watch on the victim (DOT 1984, Guide
57).
-------
CAS Registry Number: 77-81-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TABUN
CAS Registry Number: 77-81-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 127) Phosphoramido-
cyanidic Acid, Dimethyl-, Ethyl Ester; Dimethylamidoethoxyphosphoryl Cyanide;
Dimethylphosphoramidocyanidic Acid, Ethyl Ester; Ethyl Dimethylamidocyano-
phosphate; Ethyl N,N-Dimethylphosphoramidocyanidate; Ethyl N,N-Dimethylamino
Cyanophosphate; GA; LE-100; MCE; T-2104; TL 1578
Chemical Formula: C5H11N2O2p
Molecular Weight: 162.15
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LD50 skin (mouse) 1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 464°F, 240°C (Merck 1983, p. 1297)
Specific Gravity (H2O=1): 1.073 (U.S. Army 1975, p. 3-2)
Vapor Pressure (mmHg): 0.07 at 25°C (U.S. Army 1975, p. 3-2)
Melting Point: -58°F, -50°C (Merck 1983, p. 1297)
Vapor Density (AIR=1): 5.63 (U.S. Army 1975, p. 3-2)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (Merck 1976, p. 1297).
-------
CAS Registry Number: 77-81-6
Page 2 of 4
TABUN
SECTION II (continued)
Appearance and Odor: Colorless to brown liquid; faint fruity odor (U.S.
Army 1975, p.3-2)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (U.S. Army 1975, p. 3-2)
Skin: Yes (U.S. Army 1975, p. 3-2)
Ingestion: Yes (U.S. Army 1975, p. 3-2)
Health Hazards (Acute, Delayed, and Chronic): This material is toxic by
inhalation and by absorption through skin and eyes. The lethal dose for
humans may be as low as 0.01 mg/kg (Merck 1983, p. 1297). Tabun is a nerve
agent; it acts as a cholinesterase inhibitor. The median lethal dosage
(respiratory) is 400 mg-minute/m3 for humans; the median incapacitating
dosage is 300 mg-minute/m3. Respiratory lethal dosages kill in 1 to 10
minutes; liquid in the eye kills nearly as rapidly. Skin absorption great
enough to cause death may occur in 1 to 2 minutes, but may be delayed for 1
to 2 hours (U.S. Army 1975, p. 3-3).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 172°F (Sax 1984, p. 1335)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Poison A, Liquid) Extinguish
with alcohol foam, carbon dioxide, or dry chemical (Student 1981, p. 56)
Special Fire Fighting Procedures: Complete protection required; have
available decontaminants (bleach, alkali) and atropine (U.S. Army 1975, p.
3-2). Bleaching powder (chlorinated line) destroys Tabun but gives rise to
cyanogen chloride (Merck 1983, p. 1297).
Unusual Fire and Explosion Hazards: Extremely poisonous (Merck 1983, p.
1297). (Non-Specific — Poison A, Liquid) Keep away from sparks, flames,
and sources of ignition. Keep out of water sources and sewers (Student
1981, p. 56).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 77-81-6
Page 3 of 4
TABUN
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (U.S. Army 1975, p. 3-3)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Avoid water and acids (U.S. Army
1975, p. 3-2). Can react with oxidizing materials (Sax 1984, p. 1335).
Hazardous Decomposition or Byproducts: Hydrolysis forms hydrogen cyanide
(U.S. Army 1975, p. 3-2). When heated to decomposition, it emits very
toxic fumes of oxides of phosphorus and nitrogen (Sax 1984, p. 1335).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is a chemical warfare agent (Merck 1983, p. 1297).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poison A, Liquid) When handling, avoid breathing vapors,
keep upwind, avoid bodily contact with the material, and upon skin contact
wash with soap and water (Student 1981, p. 56). Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 77-81-6
Page 4 of 4
TABUN
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nerve agent symptoms include difficulty
in breathing, drooling, nausea, vomiting, cramps, involuntary defecation
and urination, twitching, jerking, staggering, headache, confusion,
drowsiness, coma, and convulsion. Inhalation causes dimness of vision and
pinpointing of the pupils (U.S. Army 1975, p. 3-2).
Emergency and First Aid Procedures: The toxic effects of tabun are
similar to parathion (Sax 1984, p. 1335). First aid for parathion is as
follows: move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
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CAS Registry Number: 78-00-2
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TETRAETHYLLEAD
CAS Registry Number: 78-00-2
Synonyms: Lead, Tetraethyl-; NCI-C54988; Plumbane, Tetraethyl-; TEL;
Tetraethyl Lead, Liquid; Tetraethyl Lead; Tetraethylplumbane
Chemical Formula: C8H20Pb
Molecular Weight: 323.45
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LD50 oral (rat) 12.3 mg/kg
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): In Lead Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: About 392°F, 200°C (*Merck 1983); decomposes between 110
and 200°C (Verschueren 1983, p. 1085)
Specific Gravity (H2O=1): 1.653 at 20°C (*Merck 1983)
Vapor Pressure (mmHg): 0.2 at 20°C (*IARC 1972-1985)
Melting Point: -202°F, -130°C (*IARC 1972-1985)
Vapor Density (AIR=1): 8.6 (NFPA 1984, p. 325M-86)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*IARC 1972-1985)
Appearance and Odor: Colorless liquid with a pleasant odor (Hawley 1981,
p. 1006)
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CAS Registry Number: 78-00-2
• Page 2 of 3
TETRAETHYLLEAD
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 0.075 mg (lead)/m3 (NIOSH 1987, p.220)
ACGIH TLV: 0.100 mg (lead)/m3 (skin) (ACGIH 1986-87, p.30)
IDLH: 40 mg (lead)/m3 (NIOSH 1987, p. 220)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Venugopal 1978)
Skin: Yes (*Venugopal 1978)
Ingestion: Yes (*Venugopal 1978)
Health Hazards (Acute, Delayed, and Chronic): Extremely poisonous; may be
fatal if inhaled, swallowed, or absorbed from the skin. Contact may cause
burns to skin and eyes (*DOT 1984). Most symptoms-of poisoning are due to
the effects of tetraethyllead on the nervous system (*Gilman 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 200°F (no method given) (NFPA 1984, p. 325M-86)
Flammable Limits:
LEL: 1.8 percent by volume (NFPA 1984, p. 325M-86)
UEL: Not Found
Extinguishing Methods: Water spray may be used because the material can
be cooled below its flash point (*NFPA 1978).
Special Fire Fighting Procedures: Fire fighting should be done from an
explosive-resistant location. Use water from unmanned monitors and
hose-holders to keep fire-exposed containers cool. When stopping leak, use
water spray to protect firefighters (*NFPA 1978). Runoff from fire control
or dilution water may cause pollution (*DOT 1984).
Unusual Fire and Explosion Hazards: May explode in fires (*CHRIS 1978).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*IARC 1972-1985)
Stable:
Conditions to Avoid: Decomposes slowly at room temperature and more
rapidly at elevated temperatures (*IARC 1972-1985).
Incompatibility (Materials to Avoid): Not Found
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CAS Registry Number: 78-00-2.
Page 3 of 3
TETRAETHYLLEAD
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Virtually all of the tetraethyllead produced in the USA is used as an
antiknock additive for gasolines (*IARC 1972-1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Tetraethyllead is hazardous, but areas may be entered with extreme care.
No skin surface should be exposed. Use water spray to disperse vapors
(*NFPA 1978). Outdoors, stay upwind and keep out of low areas.
Isolate hazard area (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 78-00-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
TETRAETHYLLEAD
(78-00-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless, oily liquid.
Odor - Pleasant, sweet odor.
Commercial Form - 98% pure liquid dyed red or other distinctive color.
Uses - Aviation gasoline, antiknock agent, ethylating agent.
Materials to Avoid - Oxidizers.
Caution: Flammable liquid. When burned, toxic fumes of lead oxide will be
emitted. Avoid sources of extreme heat or ignition including sparks or fire.
Other Names - Lead tetraethyl, tetraethylplumbane, TEL.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbitol, mannitol, dexamethasone.
Signs and Symptoms of Acute Tetraethyllead Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and symptoms of acute exposure to tetraethyllead may be severe and
include anxiety, irritability, insomnia, violent/frightening dreams, headache,
disorientation, hyperexcitability, delusions, and hallucinations. Muscular
weakness, ataxia, tremors, convulsions, cerebral edema, and coma may occur.
A metallic taste may be noted. Sneezing, bronchitis, and pneumonia may be
observed. Bradycardia (slow heart rate), hypotension (low blood pressure),
hypothermia, and pallor may also occur. Gastrointestinal symptoms include
vomiting and diarrhea. Tetraethyllead may irritate moist skin, eyes, and
mucous membranes.
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CAS Registry Number: 78-00-2
Page 2 of 3
TETRAETHYLLEAD
Emergency Life-Support Procedures:
Acute exposure to tetraethyllead may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to tetraethyllead.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to tetraethyllead.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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CAS Registry Number: 78-00-2
Page 3 of 3
TETRAETHYLLEAD
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 78-34-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIOXATHION
CAS Registry Number: 78-34-2
Synonyms: l,4-Dioxan-2,3-diyl Bis(O,O-Diethyl Phosphorothiolothionate);
l,4-Dioxan-2,3-Diyl O,O,O',0'-Tetraethyl Di(Phosphorodithioate); 1,4-Dioxane-
2,3-S,S'-Bis(O,O-Diethyl Dithiophosphate); 2,3-Bis(Diethoxyphosphinothioylthio)-
1,4-Dioxane; 2,3-Dioxane S,S-Bis(O,O-Diethylphosphorodithioate); 2,3-
Dioxanedithiol S,S-Bis(O,O-Diethyl Phosphorodithioate); AC 528; Bercotox;
Delnatex; Delnav; Dioxation; Dioxothion; ENT 22,897; Hercules 528; Hercules
AC528; Kavadel; Navadel; NCI-C00395; p-Dioxane-2,3-Dithiol, S,S-Diester with
O,O-Diethyl Phosphorodithioate; p-Dioxane-2,3-diyl Ethyl Phosphorodithioate;
Phosphorodithioic Acid, S,SM,4-Dioxane-2,3-diyl O,O,O',O'-Tetraethyl Ester;
Phosphorodithioic Acid, S,S'-p-Dioxane-2,3-diyl O,O,O',O'-Tetraethyl Ester;
Ruphos
Chemical Formula: C12H26O6P2S4
Molecular Weight: 456.54
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC50 inhalation (mouse) 0.34 mg/liter/1 hour (*NIOSH/RTECS 1985).
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.257 at 26°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: -4°F, -20°C (*Merck 1983)
Vapor Density (AIR=»1): Not Found
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CAS Registry Number: 78-34-2
Page 2 of 4
DIOXATHION
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (*Merck 1983)
Appearance and Odor: Tan liquid (*Merck 1983). (Technical) Brown liquid
(*Martin 1974).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: 0.2 mg/m3 (skin) (ACGIH 1985, p. 17)
IDLH: Not Found
Other Limits Recommended: ADI 0.0015 mg/kg (*Hayes 1975).
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (Farm Chemicals Handbook 1984, p. C-82)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): Very toxic. Probable oral
lethal dose for humans is 50-500 mg/kg or between 1 teaspoonful and 1 oz.
for a 70 kg (150 Ib.) person (*Gosselin 1976). It is a cholinesterase
inhibitor (*Hawley 1977). Death is primarily due to respiratory arrest
arising from failure of the respiratory center, paralysis of respiratory
muscles, intense bronchoconstriction, or all three (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
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CAS Registry Number: 78-34-2
Page 3 of 4
DIOXATHION
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Shock can shatter container,
releasing contents (*Sax 1975). (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire
may produce irritating or poisonous gases. Runoff from fire control water
may give off poisonous gases. Runoff from fire control or dilution water
may cause pollution (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stabler Yes (*ACGIH 1979)
Conditions to Avoid: Avoid alkali materials and heat. It is unstable
to iron or tin surfaces and when mixed with certain carriers (*Martin
1974).
Incompatibility (Materials to Avoid): Avoid alkali materials (*Martin
1974)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of oxides of nitrogen, phosphorus, and sulfur
(*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Dioxathion is used for control of insects and mites on grapes, citrus,
walnuts, ornamentals, apples, pears, and quince. Also used as a spray or
dip for the control of ticks, lice, hornfly, and sheep ked on cattle,
goats, sheep, and hogs (Farm Chemicals Handbook 1984, p. C-82).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Organophosphorus Pesticide, Liquid, n.o.s.) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
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CAS Registry Number: 78-34-2
Page 4 of 4
DIOXATHION
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 78-34-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIOXATHION
(78-34-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Tan liquid.
Commercial Forms - Brown emulsifiable concentrate or wettable powder.
Use - Pesticide.
Other Names - Delnatex; Delnav; Deltic; l,4-dioxan-2,3-diyl bis(O,O-diethyl
phosphorothiolothionate); Dioxation; Kavadel; Navadel.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Dioxathion Exposure:
Note: Dioxathion is a cholinesterase inhibitor.
Acute exposure to dioxathion may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) may occur
although hypertension (high blood pressure) is not uncommon. Chest pain may be
noted. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
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CAS Registry Number: 78-34-2
Page 2 of 3
DIOXATHION
Emergency Life-Support Procedures:
Acute exposure to dioxathion may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dioxathion.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dioxathion.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin area three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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CAS Registry Number: 78-34-2
Page 3 of 3
DIOXATHION
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of dioxathion is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of dioxathion may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 78-53-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - AMITON
CAS Registry Number: 78-53-5
Synonyms: (NIOSH/RTECS SYNONYMS 1983, Volume 3, p. 150) Phosphorothioic
Acid, S-(2-(Diethylamino)Ethyl) O,0-Diethyl Ester; Chipman 6200; Citram;
S-(Diethylaminoethyl) O,O-Diethyl Phosphorothioate; Diethyl
S-2-Diethylaminoethyl Phosphorothioate; (2-Diethylamino)Ethylphosphorothioic
Acid O,O-Diethyl Ester; O,O-Diethyl S-2-Diethylaminoethyl Phosphorothioate;
O,O-Diethyl S-Diethylaminoethyl Phosphorothiolate; O,O-Diethyl S-2-Diethyl-
aminoethyl Phosphorothiolate; O,O-Diethyl S-(beta-Diethylamino)Ethyl
Phosphorothiolate; O,O-Diethyl S-(2-Diethylaminoethyl) Thiophosphate; DSDP; ENT
24,980-X; Inferno; Metramac; Metramak; R-5,158; Rhodia-6200; Tetram
Chemical Formula: C10H24NO3PS
Molecular Weight: 269.38
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LD50 oral (rat) 3.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 230°F, 110°C at 0.2 mm (Sax 1984, p. 1008)
Specific Gravity (H2O=»1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=»1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 78-53-5
Page 2 of 4
AMITON
SECTION II (continued)
Solubility in Water: Not Found
Appearance and Odor: Liquid (Merck 1983, p. 73)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 1009)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1009)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally. It is a cholinesterase inhibitor (Sax 1984, p. 1009).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, can
emit toxic fumes of oxides of nitrogen, phosphorus, and sulfur (Sax 1984,
p. 1009). (Non-Specific — Organophosphorus Pesticide, Liquid, n.o.s.)
Container may explode in heat of fire. Fire may produce irritating or
poisonous gases. Runoff from fire control water may give off poisonous
gases. Runoff from fire control or dilution water may cause pollution (DOT
1984, Guide 55).
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CAS Registry Number: 78-53-5
Page 3 of 4
AMITON
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Extreme heat (Sax 1984, p. 1009)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Very toxic nitrogen oxides,
phosphorus oxides, and sulfur oxides when heated to decomposition (Sax
1984, p. 1009).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an acaricide and insecticide (Farm Chemicals
Handbook 1984, p. C222).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, Liquid, n.o.s.) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 78-53-5
Page 4 of 4
AMITON
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: The toxic effects are similar to
parathion (Sax 1984, p. 1009). Symptoms of parathion poisoning include
anorexia, nausea, vomiting, diarrhea, excessive salivation, pupillary
constriction, bronchoconstriction, muscle twitching, convulsions, coma,
respiratory failure. Effects are cumulative (Sax 1984, p. 2119).
Emergency and First Aid Procedures: Effects are similar to those of
parathion (Sax 1984, p. 1009). First aid procedures for parathion are as
follows: move victim to fresh air; call emergency medical care. If not
breathing, perform artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
-------
CAS Registry Number: 78-71-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - OXETANE, 3,3-BIS(CHLOROMETHYL)-
CAS Registry Number: 78-71-7
Synonyms: (NIOSH/RTECS 1985 Synonyms On-Line File) 3,3-Bis
(Chloromethyl)Oxetane; Penton; 3,3-bis(Chloromethyl)-1 -Oxacyclobutane
Chemical Formula: C5H8C120
Molecular Weight: 155
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC60 inhalation (mouse) 0.2 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 217°F, 103°C at 30 mmHg (Beilstein 1974, Volume 17/1,
p. 68)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 66°F, 19°C (Beilstein 1974, Volume 17/1, p. 68)
Vapor Density (AIR=«1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 78-71-7
Page 2 of 3
OXETANE, 3,3-BIS(CHLOROMETHYL)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 78-71-7
Page 3 of 3
OXETANE, 3,3-BIS(CHLOROMETHYL)
SECTION VI - USE INFORMATION
Penton is the trademark for a thermoplastic resin derived from
3,3-bis(chloromethyl)oxetane. Penton is a linear polymer used for solid and
lined valves, pumps, pipe and fittings, and a monofilament for filter
supports and column packing (Hawley 1981, p. 785).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS:
Sources searched but no information found:
Weast 1979
Merck 1983
Sax 1984
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
Doull 1980
Clayton and Clayton 1981-82
Encyc Occupat Health and Safety 1983
CHRIS 1978
Hayes 1982
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CAS Registry Number: 78-82-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ISOBUTYRONITRILE
CAS Registry Number: 78-82-0
Synonyms: 2-Methylpropanenitrile; 1-Cyano-l-Methylethane; 2-Cyanoprbpane;
2-Methylpropane Nitrile; 2-Methylpropionitrile; Dimethylacetonitrile; Isopropyl
Cyanide; Isopropyl Nitrile; Isopropylcyanide; Propanenitrile, 2-Methyl-;
Propanoic Acid, 2-Methyl-, Nitrile
Chemical Formula: C4H7N
Molecular Weight: 69.1
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LD50 oral (mouse) 25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 219°F, 103.8°C (*Weast 1979)
Specific Gravity (H2O=1): 0.7608 at 30°C/4°C (*Weast 1979); 0.733 at 20°C
(*Hawley 1977)
Vapor Pressure (mmHg): Not Found
Melting Point: -96.7°F, -71.5°C (*Weast 1979)
Vapor Density (AIR=1): 2.38 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly (*Weast 1979)
Appearance and Odor: Colorless liquid (*Hawley 1977)
-------
CAS Registry Number: 78-82-0
Page 2 of 4
ISOBUTYRONITRILE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Occupational exposure to nitriles —
recommended standard in air: TWA 22 mg/ms (*NIOSH/RTECS 1985).
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 577)
Skin: Yes (Hawley 1981, p. 577)
Ingestion: Yes (Hawley 1981, p. 577)
Health Hazards (Acute, Delayed, and Chronic): Poisonous; may be fatal if
inhaled, swallowed, or absorbed through skin. Contact may cause burns to
skin and eyes (DOT 1984, Guide 28). (Non-Specific - Nitriles) Primarily,
they are skin and eye irritants. Large doses cause collapse and stop
breathing (Clayton and Clayton 1981-82, p. 4846).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 47°F, 8°C (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, foam, or fog (DOT 1984, Guide 28).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
positive pressure breathing apparatus and special protective clothing.
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire. Move container from fire area if you can do so without risk. Dike
fire control water for later disposal; do not scatter the material. Spray
cooling water on containers that are exposed to flames until well after
fire is out. Withdraw immediately in case of rising sound from venting
safety device or any discoloration of tank due to fire (DOT 1984, Guide
28).
Unusual Fire and Explosion Hazards: Vapor may explode if ignited in an
enclosed area (Weiss 1980, p. 531). Toxic oxides of nitrogen are produced
during combustion (Student 1981, p. 297). It is a flammable/combustible
material and may be ignited by heat, sparks, or flames. Vapors may travel
to a source of ignition and flash back. Container may explode in heat of
fire. Vapor explosion and poison hazard indoors, outdoors or in sewers.
Runoff to sewer may create fire or explosion hazard (DOT 1984, Guide 28).
NFPA Flammability Rating: 3
-------
CAS Registry Number: 78-82-0
Page 3 of 4
ISOBUTYRONITRILE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 531)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of oxides of nitrogen (Sax 1984, p. 1639).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 531)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used in organic synthesis (*Patty 1963); as an intermediate for
insecticides (Hawley 1981, p. 577); and as a gasoline additive (Clayton and
Clayton 1981-82, p. 4873).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep sparks, flames, and other sources of ignition away. Keep material out
of water sources and sewers. Build dikes to control flow as necessary.
Attempt to stop leak if this can be done without hazard. Use water spray
to disperse vapors and dilute standing pools of liquid. Avoid breathing
vapors. Keep upwind. Avoid bodily contact with the material. Do not
handle broken packages without protective equipment. Wash away any
material which may have contacted the body with copious amounts
of water or soap and water (Student, 1981, p. 297). Wear positive
pressure breathing apparatus and special protective clothing. Shut
off ignition sources; no flares, smoking, or flames in hazard area.
Do not touch spilled material. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent
material and place into containers for later disposal. Large spills:
dike far ahead of spill for later disposal (DOT 19^4, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 78-82-0
Page 4 of 4
ISOBUTYRONITRILE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 78-82-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
ISOBUTYRONITRILE
(78-82-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Isobutyronitrile toxicity can occur via ingestion, dermal/eye
contact, or inhalation; death may occur within minutes. IMMEDIATELY begin
administering 100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Form - Colorless liquid.
Commercial Form - Liquid in tank cars.
Uses - Chemical intermediate, pesticide intermediate, gasoline additive.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. Isobutyronitrile will liberate toxic nitrogen oxide
fumes when heated to decomposition.
Other Names - 1-Cyano-l-methylethane, isopropyl cyanide, isopropyl nitrile,
2-methylpropane nitrile.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, saline cathartic or
sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote kit (amyl
nitrite ampule, sodium nitrite, sodium thiosulfate), sodium bicarbonate,
diazepam, phenytoin.
Signs and Symptoms of Acute Isobutyronitrile Exposure:
Warning: Heart palpitation may occur within minutes after exposure. High
doses can stop breathing. Vital signs should be monitored closely. Caution is
advised.
-------
EFATG
CAS Registry Number: 78-82-0
Page 2 of 3
ISOBUTYRONITRILE
Signs and symptoms of acute exposure to isobutyronitrile may include
hypertension (high blood pressure) and tachycardia (rapid heart rate),
followed by hypotension (low blood pressure) and bradycardia (slow heart rate).
Cherry-red (and potentially bloody) mucous membranes, cardiac arrhythmias, and
other cardiac abnormalities are common. Cyanosis (blue tint to skin and mucous
membranes) may also be found.
Tachypnea (rapid respiratory rate) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may occur. Headache, vertigo (dizziness),
agitation, giddiness, salivation, nausea, and vomiting may be followed by
combative behavior, convulsions, and coma.
Isobutyronitrile is irritating to the skin and mucous membranes. Lacrimation
(tearing) and a burning sensation of the mouth and throat are common.
Emergency Life-Support Procedures:
Acute exposure to isobutyronitrile may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to isobutyronitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with isobutyronitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to isobutyronitrile.
-------
EFATG
CAS Registry Number: 78-82-0
Page 3 of 3
ISOBUTYRONITRILE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with isobutyronitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
3. RUSH to a health care facility!
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Remove contaminated clothing as soon as possible.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with isobutyronitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
2. RUSH to a health care facility!
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
-------
CAS Registry Number: 78-94-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL VINYL KETONE
CAS Registry Number: 78-94-4
Synonyms: l-Buten-3-one; 2-Butenone; 3-Buten-2-one; 3-Butene-2-one; Acetone,
Methylene-; Acetyl Ethylene; Butenone; Delta(3)-2-Butenone; Gamma-Oxo-
Alpha-Butylene; Ketone, Methyl Vinyl; Methylene Acetone; Methylvinyl Ketone;
Vinyl Methyl Ketone
Chemical Formula: C4H6O
Molecular Weight: 70.09
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
LC50 inhalation (rat) 0.007 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds) (statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 179°F, 81.4°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8636 at 20°C/4°C; 0.8407 at 25°C/4°C (*Merck
1983)
Vapor Pressure (mmHg): Not Found
Melting Point: 20°F, -7°C (*CHRIS 1978)
Vapor Density (AIR=«1): 2.41 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Merck 1983)
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CAS Registry Number: 78-94-4
Page 2 of 4
METHYL VINYL KETONE
SECTION II (continued)
Appearance and Odor: Colorless liquid (*Hawley 1981) with pungent odor
(*Merck 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Similar to other ketones) (*Rumack
1975 to Present)
Skin: Yes (*Merck 1983)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is readily
absorbed through the skin, causing general poisoning (*Merck 1983) similar
to other ketones; inhalation has central nervous system depressant effects
(*Rumack 1975 to Present). It is irritating to mucous membranes and
respiratory tract (*Merck 1983) and to the skin; it is a lachrymator and
can cause eye injury (*Grant 1974).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 20°F, -6.6°C (CC) (*Hawley 1981);
30°F, -U°C (OC) (*CHRIS 1978)
Flammable Limits:
LEL: 2.1% (*NFPA 1978)
UEL: 15.6% (*NFPA 1978)
Extinguishing Methods: Use dry chemical, alcohol foam, 'or carbon dioxide.
Water spray may be ineffective as an extinguishing agent (*NFPA 1978).
Small fires: dry chemical, carbon dioxide, and foam. Large fires: fog or
foam. Move container from fire area if you can do so without risk. Dike
fire control water for later disposal; do not scatter the material. Spray
cooling water on containers that are exposed to flames until well after
fire is out. Withdraw immediately in case of rising sound from venting
safety device or any discoloration of tank due to fire (DOT 1984, Guide
28).
Special Fire Fighting Procedures: Use water to keep fire-exposed
containers cool (*NFPA 1978). Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Wear positive
pressure breathing apparatus and special protective clothing. Isolate for
-------
CAS Registry Number: 78-94-4
Page 3 of 4
METHYL VINYL KETONE
SECTION IV (continued)
1/2 mile in all directions if tank car or truck is involved in fire (DOT
1984, Guide 28).
Unusual Fire and Explosion Hazards: Vapors form flammable mixtures with
air, and may travel a considerable distance to a source of ignition and
flash back. Polymerization may take place in containers, possibly with
violent rupture of containers (*NFPA 1978). Upon exposure to heat or
flame, it emits toxic and irritating fumes (*Sax 1979). Container may
explode in heat of fire. Vapor explosion and poison hazard indoors,
outdoors, or in sewers (DOT 1984, Guide 28).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Polymerizes on standing (*Merck 1983)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Yes (*NFPA 1978)
May Not Occur:
Conditions to Avoid: Heat or sunlight (*NFPA 1978)
SECTION VI - USE INFORMATION
This material is used as an alkylating agent, a starting material for
plastics, and an intermediate in the synthesis of steroids and Vitamin A
(*Merck 1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Isolate area. Stay upwind;
keep out of low areas. Shut off ignition sources; no flares,
smoking, or flames in hazard area. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Absorb small spills with sand or other noncombustible absorbent material
and place into containers for later disposal. For large spills, dike far
ahead for later disposal (*DOT 1984).
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CAS Registry Number: 78-94-4
Page 4 of 4
METHYL VINYL KETONE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE POOR/LIMITED**
Neoprene POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton POOR/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Liquid or high concentration of vapors
causes blistering of the skin (*NFPA 1978). Similar to other ketones; can
cause sore throat, sneezing, coughing, and salivation. Inhalation may
cause nausea and vomiting; inhalation of high concentrations can cause
headache, dizziness, fainting, tremor, uncoordination, lowered body
temperature, depressed respiratory and heart rate, gasping, coma, and
death. Direct aspiration of liquid into lungs can cause chemical
pneumonia. (*Rumack 1975 to Present)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at site. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Keep victim
quiet and maintain normal body temperature. Effects may be delayed; keep
victim under observation (*DOT 1984).
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CAS Registry Number: 78-97-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - LACTONITRILE
CAS Registry Number: 78-97-7
Synonyms: 2-Hydroxypropanenitrile; 2-Hydroxypropionitrile; Acetaldehyde
Cyanohydrin; Acetocyanohydrin; alpha-Hydroxypropionitrile; Ethylidene
Cyanohydrin; Propanenitrile, 2-Hydroxy-; Propanoic Acid, 2-Hydroxy-, Nitrile
Chemical Formula: C3H5NO
Molecular Weight: 71
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(rabbit) 20 mg/kg
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 360-363°F, 182-184°C; slight decomposition (Weast 1979, p.
C-456)
Specific Gravity (H2O=1): 0.9877 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 10 at 74°C (*Patty 1963)
Melting Point: -40°F, -40°C (*Weast 1979)
Vapor Density (AIR-1): 2.45 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in all proportions (*Weast 1979)
Appearance and Odor: Straw colored liquid (*Patty 1963)
-------
CAS Registry Number: 78-97-7
Page 2 of 3
LACTONITRILE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and Safety
1971)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
Ingestion: Yes (*Encyc Occupat Health and Safety
1971)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic by oral,
skin, or eye contact (*Patty 1963)
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 170°F (TCC) (Sax 1984, p. 1683)
Flammable Limits: Moderate when exposed to heat or flame (*Encyc Occupat
Health and Safety 1971)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Foam, carbon dioxide, dry chemical (Sax 1984, p.
1683).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Cyanide fumes released when heated to
decomposition (*Encyc Occupat Health and Safety 1971).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Alkali (*Hawley 1977); oxidizing
material (Sax 1984, p. 1683).
Hazardous Decomposition or Byproducts: Cyanide fumes when heated to
decomposition (*Encyc Occupat Health and Safety 1971); hydrocyanic acid in
presence of alkali (*Hawley 1977).
-------
CAS Registry Number: 78-97-7
Page 3 of 3
LACTONITRILE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Solvent — intermediate in production of ethyl lactate and lactic acid
(*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapors or touch spilled material (see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 78-97-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
LACTONITRILE
(78-97-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Lactonitrile toxicity can occur via ingestion, dermal/eye contact, or
ingestion; death may occur within minutes. IMMEDIATELY begin administering
100% oxygen and rush victims to a health care facility.
Substance Characteristics:
Pure Form - Straw-colored liquid.
Commercial Form - 95 to 97% pure liquid in carboys.
Uses - Chemical intermediate, solvent.
Materials to Avoid - Alkali, oxidizers.
Caution: Toxic hydrogen cyanide gas may be released upon contact with alkali
or when heated to decomposition.
Other Names - Acetaldehyde cyanohydrin, ethylidene cyanohydrin,
2-hydroxypropanenitrile, 2-hydroxypropionitrile.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulfate), sodium
bicarbonate, diazepam, phenytoin.
Signs and Symptoms of Acute Lactonitrile Exposure:
Warning: Heart palpitations may occur within minutes after exposure. Caution
is advised. Vital signs should be monitored closely. Symptoms may be delayed.
Signs and symptoms of acute exposure to lactonitrile may include hypertension
(high blood pressure) and tachycardia (rapid heart rate), followed by
hypotension (low blood pressure) and bradycardia (slow heart rate). Cherry-red
mucous membranes and blood, cardiac arrhythmias, and other cardiac
abnormalities are common."7 Cyanosis (blue tint to the skin and mucous
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CAS Registry Number: 78-97-7
Page 2 of 3
LACTONITRILE
membranes) may be present following exposure to lactonitrile. Salivation,
nausea, and vomiting may also occur.
Tachypnea (rapid respiratory rate) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may occur. Headache, vertigo (dizziness),
agitation, and giddiness may be followed by combative behavior, convulsions,
paralysis, protruding eyeballs, dilated and unreactive pupils, and coma.
Lactonitrile is irritating to the skin and mucous membranes. Lacrimation
(tearing) and a burning sensation of the mouth and throat are common.
Emergency Life-Support Procedures:
Acute exposure to lactonitrile may require decontamination and life support for
the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to lactonitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with lactonitrile-contaminated
persons or their gastric contents may result in self-poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to lactonitriie.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
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CAS Registry Number: 78-97-7
Page 3 of 3
LACTONITRILE
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with lactonitrile-contaminated
persons or their gastric contents may result in self-poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with lactonitrile-contaminated
persons or their gastric contents may result in self-poisoning.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. DO NOT induce vomiting. Ipecac is not recommended for ingestion of
lactonitrile.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
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CAS Registry Number: 79-06-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ACRYLAMIDE
CAS Registry Number: 79-06-1
Synonyms: 2-Propenamide; Acrylic Amide; Ethylene Carboxamide; Propenamide;
Propenoic Acid, Amide
Chemical Formula: CSH5NO
Molecular Weight: 71.08
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000/10,000 (pounds)
RQ: 5000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 189°F, 87°C at 2 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.122 at 30°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 0.007 at 20°C (*ACGIH 1980)
Melting Point: 184°F, 84.5°C (*Merck 1976)
Vapor Density (AIR=1): 2.45 (*Sax 1975)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 215.5 g/100 mL water at 30°C (*Merck 1976)
Appearance and Odor: Odorless (*Grant 1974) white, crystalline solid
(*Sax 1975).
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CAS Registry Number: 79-06-1
Page 2 of 4
ACRYLAMIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Air: TWA 0.3 mg/ms (skin) (OSHA 1984, p. 660)
ACGIH TLV: TWA 0.3 mg/ms; STEL 0.6 mg/ms (skin) (*ACGIH 1981)
IDLH: Not Found
Other Limits Recommended: NIOSH: 0.3 mg/ms 10 hr TWA (NIOSH 1987, p.46).
It is recommended that no more than 0.05 mg/kg/day be absorbed by workers
(*ACGIH 1980). Suspected of carcinogenic potential in humans; notice of
intent to change to 0.03 mg/ms for 1985-86 (ACGIH 1985, p. 42).
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 43)
Skin: Yes (*Hamilton 1974)
Ingestion: Yes (NIOSH/OSHA 1978, p. 43)
Health Hazards (Acute, Delayed, and Chronic): Classified as very toxic;
probable oral lethal human dose is between 50 and 500 mg/kg or between. 1
teaspoon and 1 ounce for a 150 Ib. person (Gosselin 1984, p. 11-409).
Polymerized acrylamide is not toxic, but the monomer can cause peripheral
nerve damage (*Doull 1980). It is a cumulative neurotoxin and repeated
exposure to small amounts may cause serious injury to the nervous system
(*Rumack 1975 to Present). The neurological effects may be delayed.
Polymer inhibitors or stabilizers added to the monomer may also produce
toxicity (*Peer Review Committee). The symptoms of acrylamide toxicity are
consistent with mid-brain lesions (*Hamilton 1974) and blocked transport
along both motor and sensory axons (*Doull 1980).
Medical Conditions Generally Aggravated by Exposure: Individuals with
nervous system diseases should not be exposed to acrylamide (*Plunkett
1976).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 138°C (CC) (*Sunshine 1969)
Flammable Limits:
LEL: Not Found;
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray or foam. For large fires use water spray, fog or foam. Move
container from fire area if you can do so without risk (*DOT 1984).
Special Fire Fighting Procedures: Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material (*DOT
1984).
Unusual Fire and Explosion Hazards: Heating to decomposition evolves
ammonia, hydrogen and carbon monoxide (*Rumack 1975 to Present).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 79-06-1
Page 3 of 4
ACRYLAMIDE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Hawley 1977)
Conditions to Avoid: Heat (*ACGIH 1980); ultraviolet light (*Merck
1976).
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
P. 42).
Hazardous Decomposition or Byproducts: Pure acrylamide will decompose at
175-300°C giving ammonia, hydrogen and carbon monoxide (*Rumack 1975 to
Present).
Hazardous Polymerization: May Occur: Yes (*ACGIH 1980)
May Not Occur:
Conditions to Avoid: It readily polymerizes when heated to the
melting point or when exposed to ultraviolet light (*Merck 1976). It
is known to polymerize with violence when heated (*ACGIH 1980).
SECTION VI -- USE INFORMATION
Reactive monomer and intermediate in production of organic chemicals,
polymers or copolymers (*ACGIH 1980); the latter are used as or in
flocculants for sewage and waste treatment; soil conditioning agents; ore
processing; adhesives; paper and textile industries; permanent press
fabrics (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent materal and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 79-06-1
Page 4 of 4
ACRYLAMIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
Viton POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 79-06-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
ACRYLAMIDE
(79-06-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystalline solid.
Odor - None.
Commercial Form - Shipped in fiber drums.
Uses - Manufacture of polymers, dyes, and adhesives; flocculant for sewage and
waste treatment; soil conditioning; ore processing.
Caution: Avoid sources of heat including fire. Acrylamide will polymerize
violently when heated.
Other Names - Acrylic amide, ethylene carboxamide, 2-propenamide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Acrylamide Exposure:
Warning: Effects may be delayed. Caution is advised.
Acrylamide is a cumulative neurotoxin. Signs and symptoms of acute exposure
may include drowsiness, fatigue, memory loss, confusion, hallucinations,
tingling of fingers, loss of vibration and position senses, tremor, muscular
weakness, disturbances of balance (especially with the eyes closed), and
dysarthria (incoordination of the muscles used for speaking).
Excessive sweating of the feet and hands may also occur. Contact with
acrylamide may irritate or burn the skin, eyes, and mucous membranes.
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CAS Registry Number: 79-06-1
Page 2 of 3
ACRYLAMIDE
Emergency Life-Support Procedures:
Acute exposure to acrylamide may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to acrylamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to acrylamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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CAS Registry Number: 79-06-1
Page 3 of 3
ACRYLAMIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 79-11-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHLOROACETIC ACID
CAS Registry Number: 79-11-8
Synonyms: Acetic Acid, Chloro-; alpha-Chloroacetic Acid; Chloracetic Acid;
Chloroethanoic Acid; MCA; MKHUK; Monochloracetic Acid; Monochloroacetic Acid;
Monochloroacetic Acid Solution; Monochloroethanoic Acid; NCI-C60231
Chemical Formula: C2H3C1O2
Molecular Weight: 94.50
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.18 mg/L
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 372°F, 189°C (*Merck 1976)
Specific Gravity (H2O=1): 1.4043 at 40°C (*Weast 1979)
Vapor Pressure (mmHg): 1 at 43°C (*Patty 1963)
Melting Point: 145°F, 63°C (*Weast 1979)
Vapor Density (AIR=1): 3.26 (*Sax 1975)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble in water (*Weast 1979)
Appearance and Odor: Colorless or white crystals (*Merck 1976).
Colorless to light brown crystals (*Hawley 1977).
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CAS Registry Number: 79-11-8
Page 2 of 4
CHLOROACETIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
Ingestion: Yes (*Encyc Occupat Health and Safety
1971)
Health Hazards (Acute, Delayed, and Chronic): This material is very
toxic. The probable lethal oral dose is 50-500 mg/kg of body weight,
between one teaspoon and one ounce, for a 150 Ib. person. Chloroacetic
acid is irritating to the skin, cornea, and respiratory tract and causes
burns. It may severely damage skin and mucous membranes. Ingestion may
interfere with essential enzyme systems and cause perforation and
peritonitis. Burns to skin result in marked fluid and electrolyte loss.
Death may follow if more than 3% of the skin is exposed to this material.
Other health hazards include central nervous system depression, and
respiratory system depression (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Persons with lung
diseases are at greater risk (*ITI 1982).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 302°F, 150°C (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Water fog applied gently to surface will cause
frothing which will extinguish fire. Normal fire fighting procedures may
be used (*NFPA 1978). Extinguish fire using agent suitable for
surroundings. Material itself does not burn or burns with difficulty.
(*Student 1981) For small fires use dry chemical, carbon dioxide, water
spray or foam. For large fires use water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: This material is extremely hazardous to
health, but fire fighters may enter areas with extreme care. Full
protective clothing including a self-contained breathing apparatus, coat,
pants, gloves, boots and bands around legs, arms and waist should be
provided. No skin surface should be exposed (*NFPA 1978). Cool
fire-exposed containers with water (*Student 1981). Move container from
fire area if you can do so without risk. Spray cooling water on containers
that are exposed to flames until well after fire is out (*DOT 1984).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes of phosgene and chlorides (*Sax 1975). Water may
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CAS Registry Number: 79-11-8
Page 3 of 4
CHLOROACETIC ACID
SECTION IV (continued)
cause frothing if it gets below surface of the liquid and turns to steam
(*NFPA 1978). Flammable/poisonous gases may accumulate in tanks and hopper
cars. Some of these materials may ignite combustibles, e.g., wood, paper,
oil (*DOT 1984).
NFPA Flammability Rating: 1
SECTION V « REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Heating (*Sax 1975)
Incompatibility (Materials to Avoid): It is corrosive to metals (*Student
1981).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of phosgene and chlorides (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Chloroacetic acid is used as a pre-emergence herbicide. It is also used as
a defoliant (*Martin and Worthing 1974). It is an intermediate for
synthetic caffeine (*NIOSH 1984) as well as sarcosine, EDTA, and
ethylchloroacetate (*ITI 1982) and sodium carboxymethylcellulose, glycine,
thioglycolic acid, Pharmaceuticals like Vitamin A and indigoid dyes (*SRI).
Additional uses include disinfectant and as a drying agent for curing hay
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Neutralize spilled materials with crushed limestone, soda ash, or lime
(*Student 1981). Waste water containing chloroacetic acid can be treated
with ammonia, ammonium salts, or amines followed by separation of suspended
solids (*Opavsky 1976). Keep unnecessary people away; isolate hazard and
deny entry. Stay upwind; keep out of low areas. Notify authorities if
water pollution occurs. Do not touch spilled material. Stop leak if you
can without risk. Take up small spills with an absorbent, non-combustible
material and place into clean, dry containers for later disposal. Dike
large spills far ahead of spill for later disposal (*DOT 1984).
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CAS Registry Number: 79-11-8
Page 4 of 4
CHLOROACETIC ACID
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
PE POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 79-11-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
CHLOROACETIC ACID
(79-11-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless, white or light brown crystals.
Odor - Penetrating; similar to vinegar.
Commercial Forms - 99.5% pure liquid or solid in drums.
Uses - Chemical intermediate, herbicide, preservative, disinfectant, drying
agent for hay, medicinal treatment of keratoses.
Caution: Avoid sources of extreme heat including fire. Chloroacetic acid will
emit toxic fumes of phosgene and chlorides when heated to decomposition.
Other Names - Chloroethanoic acid, MCA, monochloroacetic acid.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Chloroacetic Acid Exposure:
Warning: Effects may be delayed. Caution is advised. Chloroacetic acid is
extremely corrosive.
Signs and symptoms of acute ingestion of Chloroacetic acid may be severe and
include salivation, intense thirst, difficulty in swallowing, chills, and
shock. Oral, esophageal, and stomach burns are common and often associated
with severe pain. Vomitus generally has a coffee-ground appearance. The
potential for circulatory collapse is high following ingestion of Chloroacetic
acid.
Acute inhalation exposure may result in sneezing, hoarseness, choking,
laryngitis, dyspnea (shortness of breath), respiratory tract irritation, and
chest pain. Bleeding of nose and gums, ulceration of the nasal and oral
mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur.
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CAS Registry Number: 79-11-8
Page 2 of 3
CHLOROACETIC ACID
If the eyes have come in contact with chloroacetic acid, then irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure may
result in dermatitis (red, inflamed skin), severe burns, and pain.
Emergency Life-Support Procedures:
Acute exposure to chloroacetic acid may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to chloroacetic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to chloroacetic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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CAS Registry Number: 79-11-8
Page 3 of 3
CHLOROACETIC ACID
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Instruct victims not to swallow
this water.
3. DO NOT induce vomiting or attempt to neutralize!
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are alert and conscious.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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CAS Registry Number: 79-19-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THIOSEMICARBAZIDE
CAS Registry Number: 79-19-6
Synonyms: l-Amino-2-Thiourea; 1-Aminothiourea; 2-Thiosemicarbazide;
Aminothiourea; Hydrazinecarbothioamide; Isothiosemicarbazide; N-Aminothiourea;
Thiocarbamoylhydrazine
Chemical Formula: CHSN3S
Molecular Weight: 91.15
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 9.16 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 356-363°F, 180-184°C (*Hawley 1977)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Hawley 1977)
Appearance and Odor: This compound is a white crystalline powder and is
odorless (*Hawley 1977)
-------
CAS Registry Number: 79-19-6
Page 2 of 4
THIOSEMICARBAZIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2575)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by ingestion (Sax 1984, p. 2575). May induce goiter and cause
delayed toxic effects in blood and skin (*Rumack 1975 to Present). May be
mutagenic in human cells (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous, Solid, n.o.s)
Extinguish with any chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Poisonous, Solid,
n.o.s.) Stay upwind; keep out of low areas. Wear self-contained (positive
pressure if available) breathing apparatus and full protective clothing.
Move container from fire area if you can do so without risk (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, very
toxic fumes of sulfur oxides and nitrogen oxides are emitted (Sax 1984, p.
2575).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found -;
-------
CAS Registry Number: 79-19-6
Page 3 of 4
THIOSEMICARBAZIDE
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition,
thiosemicarbazide emits very toxic fumes of oxides of sulfur and nitrogen
(Sax 1984, p. 2575).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This compound is used as a reagent for ketones and certain metals, for
photography and as a rodenticide ("Hawley 1977). It is also effective for
control of bacterial leaf blight of rice (*Nippon Noyaku Gakkaishi 1976,
1(2)95). Not a registered pesticide in the U.S. (USEPA/Active Ingredients,
1985). It is a chemical intermediate for herbicides and a reagent for
detection of metals (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid skin contact, ingestion or inhalation (see Section III above).
(Non-Specific — Poisonous Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do it without risk. Small spills: take up with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Thiosemicarbazide may induce goiter and
has also been reported to cause bone marrow depression with accompanying
decreases in white blood cells and platelets. It may also cause skin
irritation (*Rumack 1975 to Present).
Emergency and First Aid Procedures: For inhalation, remove victim to
fresh air and monitor for breathing difficulty. For eye exposure, irrigate
copiously with water for 15 minutes and follow with eye exam if pain
persists. For dermal exposure, wash skin twice with water and soap,
-------
CAS Registry Number: 79-19-6
Page 4 of 4
THIOSEMICARBAZIDE
SECTION IX (continued)
followed by exam if pain persists (*Rumack 1975 to Present). (Non-Specific
-- Poisonous, Solid, n.o.s.) Call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site (DOT 1984, Guide 53).
-------
CAS Registry Number: 79-21-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PERACETIC ACID
CAS Registry Number: 79-21-0
Synonyms: Peroxyacetic Acid; Acetyl Hydroperoxide; Hydroperoxide, Acetyl;
Peracetic Acid Solution (Sax 1984, p. 2148); Ethaneperoxoic Acid (Merck 1983,
p. 1028)
Chemical Formula: C2H4O3
Molecular Weight: 76.05
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.45 ing/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 221°F, 105°C (*Weast 1979)
Specific Gravity (H2O=1): 1.226 at 15°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 32°F, 0.1°C (*Weast 1979); approximately -22°F, -30°C
(Hawley 1981, p. 786)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (*Weast 1979)
Appearance and Odor: Colorless liquid (*NFPA 1978). Strong, pungent
acrid odor (*CHRIS 197S, *Merck 1983).
-------
CAS Registry Number: 79-21-0
Page 2 of 3
PERACETIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*NFPA 1978)
Skin: Yes (Sax 1984, p. 2148)
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): This is a very toxic
compound. The probable human oral lethal dose is 50-500 mg/kg, or between
1 teaspoon and 1 ounce for a 150 pound person (*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): (Peracetic Acid, 60% Acetic Acid Solution)
105°F, 41°C (no method given) (NFPA 1984, p. 49-72)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Fight fires from an explosion-resistant location.
In advanced or massive fires, area should be evacuated (NFPA 1984, p.
49-72). For small fires: use dry chemical, carbon dioxide, water spray,
or foam. For large fires: flood area with water (DOT 1984, Guide 51).
Special Fire Fighting Procedures: If fire occurs in the vicinity of this
compound, water should be used to keep containers cool. Cleanup and
salvage operations should not be attempted until all of the peroxyacetic
acid solution has cooled completely (NFPA 1984, p. 49-72). Keep
unnecessary people away; wear self-contained breathing apparatus and full
protective clothing (DOT 1984, Guide 51).
Unusual Fire and Explosion Hazards: Decomposes violently at 230°F, 110°C
(NFPA 1984, p. 325M-78). When heated to decomposition, this compound emits
acrid smoke and fumes (Sax 1984, p. 2148). Runoff to sewer may create a
fire or explosion hazard (DOT 1984, Guide 51).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (NFPA 1984, p. 49-72)
Stable:
Conditions to Avoid: Shock and heat (NFPA 1984, p. 49-72).
-------
CAS Registry Number: 79-21-0
Page 3 of 3
PERACETIC ACID
SECTION V (continued)
Incompatibility (Materials to Avoid): Powerful oxidizer. Isolate from
other stored material, particularly accelerators, oxidizers, and organic or
flammable materials (NFPA 1984, p. 49-72).
Hazardous Decomposition or Byproducts: Emits acrid smoke and fumes when
heated to decomposition (Sax 1984, p. 2148).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (NFPA 1984, p. 49-72)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This compound is used as a bactericide and fungicide, especially in food
processing; a reagent in making caprolactam and glycerol; an oxidant for
preparing epoxy compounds; a bleaching agent; a sterilizing agent; and a
polymerization catalyst for polyester resins (*Hawley 1981; *SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Do not touch
the spilled material; shut off all ignition sources and stop the leak
if this can be done without risk (DOT 1984, Guide 51). The spilled
material should be absorbed with a noncombustible absorbent such as
vermiculite. Sweep up and place in a metal container for immediate
disposal. Do not use spark-generating metals or organic materials for
sweeping up or handling spilled material. Dispose of the absorbed
peroxyacetic acid solution, in small quantities at a time, by placing it on
the ground in a remote outdoor area and igniting with a long torch. Empty
containers should be washed with a 10% sodium hydroxide solution (NFPA
1984, p. 49-72).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 79-21-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
PERACETIC ACID
(79-21-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Strong, pungent, acrid.
Commercial Form - 40% solution in acetic acid contained in 65-lb glass carboys
and 250-lb aluminum drums.
Uses - Bactericide, fungicide, sterilizing agent, bleaching agent,
polymerization catalyst for polyester resins, manufacture of glycerol and epoxy
compounds.
Materials to Avoid - Organic materials, olefins.
Caution: Peracetic acid is a strong oxidizer. Fire or other violent reactions
may occur upon contact with combustible organic material.
Other Names - Acetic peroxide, acetyl hydroperoxide, Desoxon 1, ethaneperoxoic
acid, Obson AC, peroxyacetic acid.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Peracetic Acid Exposure:
Signs and symptoms of acute ingestion of peracetic acid may include corrosion
of mucous membranes of mouth, throat, and esophagus with immediate pain and
dysphagia (difficulty swallowing); ingestion may cause gastrointestinal tract
irritation. Inhalation of vapors or fumes may result in respiratory tract
irritation; peracetic acid is highly irritating to the skin and eyes.
-------
EFATG
CAS Registry Number: 79-21-0
Page 2 of 3
PERACETIC ACID
Emergency Life-Support Procedures:
Acute exposure to peracetic acid may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to peracetic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to peracetic acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 79-21-0
Page 3 of 3
PERACETIC ACID
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
6. Transport to a health care facility.
-------
CAS Registry Number: 79-22-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHYL CHLOROFORMATE
CAS Registry Number: 79-22-1
Synonyms: Carbonochloridic Acid, Methyl Ester; Chlorocarbonic Acid, Methyl
Ester; Chloroformic Acid Methyl Ester; Formic Acid, Chloro-, Methyl Ester;
K-Stoff; Methoxycarbonyl Chloride; Methyl Chlorocarbonate; TL 438
Chemical Formula: C2H3C1O2
Molecular Weight: 94.50
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.185 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 160°F, 71.0°C (*Merck 1976)
Specific Gravity (H2O=1): 1.223 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 3.26 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Sax 1984, p. 1826)
Appearance and Odor: Clear liquid (*Merck 1976)
-------
CAS Registry Number: 79-22-1
Page 2 of 4
METHYL CHLOROFORMATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1826)
Skin: Yes (Sax 1984, p. 1826)
Ingestion: Yes (Sax 1984, p. 1826)
Health Hazards (Acute, Delayed, and Chronic): Methyl chloroformate is
highly toxic upon inhalation and upon ingestion (*Merck 1976; Sax 1984, p.
1826). A concentration of 1 mg/liter (190 ppm) has been lethal in 10
minutes (*Clayton and Clayton 1981-82). It is corrosive and irritating to
skin (*Hawley 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 54°F (no method given) (*Sax 1979)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, and foam. For large fires, use water spray, fog, or foam.
Move container from fire area if it can be done without risk. Cool
containers exposed to flames with water (DOT 1984, Guide 28).
Special Fire Fighting Procedures: Isolate for 1/2 mile in all directions
if tank car or truck is involved in fire. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: This chemical is very dangerous when
exposed to heat sources, sparks, flame, or oxidizers. It will react with
water or steam to produce toxic and corrosive fumes (*Sax 1979). Vapors
may travel to a source of ignition and flash back. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire (DOT 1984, Guide 28).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 79-22-1
Page 3 of 4
METHYL CHLOROFORMATE
SECTION V (continued)
Conditions to Avoid: Heat or steam should be avoided (*Sax 1979).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Toxic fumes of phosgene are
produced when the material is heated to decomposition. Will react with
water or steam to produce toxic and corrosive fumes (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Methyl chloroformate is used in organic synthesis and in manufacturing of
insecticides (*Hawley 1977). It was used as a warfare agent during World
War I (*Clayton and Clayton 1981-82).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors and contact with skin (see Section III above). In
case of contact, immediately flush skin or eyes with water. Remove and
isolate contaminated clothing. Runoff from fire control or dilution
water should be contained for later disposal. In case of a small spill,
take up with sand or other noncombustible absorbent material and place in
containers for later disposal. In case of a large spill, dike far ahead of
the spill for later disposal. In case of spills or leaks, shut off
ignition sources, and have no flares, smoking, or flames in hazard area.
Do not touch spilled material and use water spray to reduce vapors (DOT
1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 79-22-1
Page 4 of 4
METHYL CHLOROFORMATE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: It is an irritant to the skin and is
corrosive by ingestion or inhalation. Concentrations of 10 ppm have caused
lachrymation and a concentration of 190 ppm for 10 minutes has been lethal
to humans. Irritation of the lung and eyes may persist after cessation of
exposure. Skin allergies may also occur (*Clayton and Clayton 1981-82).
After 2-3 inhalations, brief initial irritation may occur followed by
massive symptoms (heavy cough) after 36 hours. Relapses may occur in
following days with eventual full recovery (*Schuckmann 1972).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If not breathing, give artificial respiration; if
breathing is difficult, provide oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact, immediately flush skin
or eyes with water for at least 15 minutes. Keep victim quiet and maintain
normal body temperature. Since effects may be delayed, keep careful watch
on the victim (DOT 1984, Guide 28).
-------
CAS Registry Number: 80-63-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL 2-CHLOROACRYLATE
CAS Registry Number: 80-63-7
Synonyms: 2-Chloroacrylic Acid, Methyl Ester; 2-Propenoic Acid, 2-Chloro-,
Methyl Ester; Acrylic Acid, 2-Chloro-, Methyl Ester; Methyl
Alpha-Chloroacrylate; Propenoic Acid, 2-Chloro-, Methyl Ester
Chemical Formula: C4H5C1O2
Molecular Weight: 120.54
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.5 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 126°F, 52°C at 51 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.189 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless liquid (*Lefaux 1968)
-------
CAS Registry Number: 80-63-7
Page 2 of 3
METHYL 2-CHLOROACRYLATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Lefaux 1968)
Skin: Yes (*Lefaux 1968)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): It is a skin, eye, and lung
irritant. The least trace on skin raises large blisters. It is also a
respiratory poison; breathing the vapors can cause pulmonary edema (*Lefaux
1968).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Fight fire from maximum distance. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Wear
positive pressure breathing apparatus and special protective clothing (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 80-63-7
Page 3 of 3
METHYL 2-CHLOROACRYLATE
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used to make acrylic high polymer with properties closely resembling those
of polymethylmethacrylate (*Lefaux 1968). Monomer for specialty polymers
(e.g., aircraft glazing) (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Liquid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Stop leak if you can do so without
risk. Use water spray to reduce vapors. Small spills: take up with sand
or other noncombustible absorbent material and place into containers for
later disposal. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: A trace on skin causes large blisters.
Inhalation of high concentrations may cause rapid breathing, headache,
nausea, lethargy, pulmonary edema, convulsions, and death (Gosselin 1984,
p. 11-409).
Emergency and First Aid Procedures: (Non-Specific — Poisonous Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. Remove and isolate contaminated clothing and shoes at the site.
In case of contact with material, immediately flush skin or eyes with
running water for at least 15 minutes. Speed in removing material from
skin is of extreme importance. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
-------
CAS Registry Number: 81-81-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ WARFARIN
CAS Registry Number: 81-81-2
Synonyms: Coumarin,3-(alpha-Acetonylbenzyl)-4-Hydroxy-; l-(4'-hydroxy-
3'-coumarinyl)-l-phenyl-3-butanone; 2H-l-benzopyran-2-one, 4-hydroxy-3-
(3-oxo-1 -phenylbutyl); 3-( 1 '-pheny 1-2'- acetylethyl)-4-hydroxycoumarin;
3-(alpha-acetonylbenzyl)-4-hydroxycoumarin; 200 Coumarin; Athrombine-K;
Brumolin; Compound 42; Coumadin; Coumafen; Coumafene; Coumarin, 3-(alpha-
acetonylbenzyl)-4-hydroxy; Coumarin, 4-hydroxy-3(l-phenyl-3-oxo-butyl)-;
Coumefene; D-Con; Dethmor; Dethnel; Eastern States Duocide; Fasco Fascrat
Powder; Frass-Ratron; Kumader; Kumadu; Kypfarin; Maag Rattentod Cum; Mar-Frin;
Maveran; Prothromadin; Rat-a-way; Rat-b-gon; Rat-Gard; Rat-Kill; Rat-Mix;
Rat-ola; Ratron; Rats-No-More; Rodafarin; Temus W; Warf 42; Warf Compound 42;
Warf-12; Warfarat; Warficide; Zoocoumarin; Co-Rax; Cov-R-Tox; Liqua-Tox;
Martin's Mar-Frin; Mouse- Pak; Rat and Mice Bait; Rat-o-cide #2; Rat-trol;
Ratorex; Ratox; Ratoxin; Ratron G; Rax; Ro-deth; Rodex, Rodex Blox; Rosex;
Rough and Ready Mouse Mix; Solfarin; Spray-trol Brand Roden-trol; Tox-Hid; Twin
light rat away; Vampirinip II & III; Waran; Warfarin plus; Warfarin Q;
3-(alpha-Phenyl-beta- Acetylethyl)-4-Hydroxycoumarin; 3-(Acetonylbenzyl)-
4-Hydroxycoumarin; 4-Hydroxy-3(3-oxo-l-Phenylbutyl)-2H-l-Benzopyran-2-one
Chemical Formula: C19H16O4
Molecular Weight: 308.32
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.32 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
-------
CAS Registry Number: 81-81-2
Page 2 of 4
WARFARIN
SECTION II (continued)
Vapor Pressure (mmHg): Not Found
Melting Point: 322°F, 161°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor: Odorless and colorless solid (*Sax 1984).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 mg/ms (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.1 mg/ms; STEL 0.3 mg/ms (*ACGIH 1980)
IDLH: 200 mg/ms (*NIOSH/OSHA 1981)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Arena 1974)
Ingestion: Yes (*Morgan 1982)
Health Hazards (Acute, Delayed, and Chronic): It is classified as very
toxic. Probable oral lethal dose in humans is 50-500 mg/kg, between 1
teaspoon and 1 ounce for a 150 Ib. person (*Gosselin 1976). Material is an
.anticoagulant. Toxic effects other than hemorrhage are rarely seen in
humans (*Goodman 1975). Material is believed to be teratogenic in humans
(*Hayes 1982).
Medical Conditions Generally Aggravated by Exposure: Persons with a
history of blood disorders with bleeding tendencies would be expected to
be at increased risk from exposure (*NIOSH/OSHA 1981).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Poison B Solid) Extinguish fire
using agent suitable for type of surrounding fire. Use alcohol foam,
carbon dioxide, or dry chemical (Student 1981, p. 416).
Special Fire Fighting Procedures: (Non-Specif ic -- Poison B Solid) Wear
full protective clothing and self-contained breathing apparatus (Student
1981, p. 416).
-------
CAS Registry Number: 81-81-2
Page 3 of 4
WARFARIN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Contact with strong oxidizers may
cause fires and explosions (*NIOSH/OSHA 1981).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers (*NIOSH/OSHA 1981)
Hazardous Decomposition or Byproducts: Toxic gases and vapors (e.g.,
carbon monoxide) may be released in heating to decomposition (*NIOSH/OSHA
1981).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Material is used as a rodenticide for Norway rats and for house mice
(*SRI).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material (see Section III above). Eating and smoking
should not be permitted in areas where it is handled, processed or stored.
For small spills: sweep onto paper or other suitable material. Place
in an appropriate container and burn in a safe place. Large quantities
may be destroyed by dissolving in a flammable solvent (e.g., alcohol) and
atomizing in a combustion chamber (*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 81-81-2
Page 4 of 4
WARFARIN
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms begin a few days or weeks after
ingestion. They include nose bleed, bleeding gums, pallor, and sometimes
hematomas around joints and on buttocks, blood in urine and feces. Later,
paralysis due to cerebral hemorrhage, and finally hemorrhagic shock and
death may occur (*Doull 1980).
Emergency and First Aid Procedures: (Non-Specific -- Coumarin Derivative
Pesticide, Solid, n.o.s.) Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 82-66-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIPHACINONE
CAS Registry Number: 82-66-6
Synonyms: . 1,3-Indandione, 2-Diphenylacetyl-; 2-(DiphenyIacetyl)-lH-Indene-
l,3(2H)-Dione; 2-(Diphenylacetyl)Indan-l,3-Dione; 2-Diphenylacetyl-l,3-
Diketohydrindene; 2-Diphenylacetyl-l,3-Indanedione; Diandin; Didandin; Didion;
Difacione; Dipaxin; Diphacin; Diphenacin; Diphenandione; Oragulant; PID;
Promar; Ramik; Ratindan 1; Solvan; U1363; lH-Indene-l,3(2H)-Dione,
2-(Diphenylacetyl)-
Chemical Formula: C23H16O3
Molecular Weight: 340.38
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mammal) 0.91 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 295-297°F, 146-147°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (*Merck 1976); 17 mg/liter
(Farm Chemicals Handbook 1984, p. C-82)
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CAS Registry Number: 82-66-6
Page 2 of 3
DIPHACINONE
SECTION II (continued)
Appearance and Odor: Pale yellow crystals (*Merck 1976); odorless (*Osol
1975)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1231)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; probable oral lethal dose in humans is 5-50 mg/kg, or between 7
drops and 1 teaspoonful for a 150-lb. person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Many medical
conditions will be aggravated by this material (*Goodman 1980).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: The material is similar to coumarin and indandione
(*Morgan 1982). (Non-Specific -- Coumarin Derivative Pesticide, Solid,
n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam.
Large fires: water spray, fog, or foam. Move container from fire area if
you can do it without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Coumarin Derivative
Pesticide, Solid, n.o.s.) Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Wear positive pressure breathing apparatus
and special protective clothing. Remove and isolate contaminated clothing
at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
acrid smoke and fumes (Sax 1984, p. 1231).
NFPA Flammability Rating: Not Found -;
-------
CAS Registry Number: 82-66-6
Page 3 of 3
DIPHACINONE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Sensitive to light (*Worthing 1979)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 1231).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Rodenticide (*Worthing 1979); and anticoagulant medication (*Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX — EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 82-66-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIPHACINONE
(82-66-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
.authority.
Substance Characteristics:
Pure Form - Pale yellow crystals.
Odor - None.
Commercial Forms - 95% pure yellow powder, 5-mg tablets.
Use - Rodenticide.
Other Names - Diandin; Didandin; Diphacin; Diphenadione; 2-diphenylacetyl-l,3-
indanedione; Promar; Ramik; Solvan.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
vitamin K (phytonadione).
Signs and Symptoms of Acute Diphacinone Exposure:
Diphacinone is an anticoagulant. Hemorrhage is the most common effect and may
be manifested by nose bleeding, gum bleeding, bloody stools and urine,
ecchymoses (extravasations of blood into skin), and hemoptysis (coughing up of
blood). Bruising is heightened. Abdominal and flank pain are also common.
Other signs and symptoms include flushing, dizziness, hypotension (low blood
pressure), dyspnea (shortness of breath), cyanosis (blue tint to the skin and
mucous membranes), fever, and diarrhea.
Emergency Life-Support Procedures:
Acute exposure to diphacinone may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment shouldf also be worn, as necessary. Rescue vehicles
-------
EFATG
CAS Registry Number: 82-66-6
Page 2 of 3
DIPHACINONE
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to diphacinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to diphacinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
-------
EFATG
CAS Registry Number: 82-66-6
Page 3 of 3
DIPHACINONE
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of diphacinone is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of diphacinone may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 86-50-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- AZINPHOS-METHYL
CAS Registry Number: 86-50-0
Synonyms: Methyl Guthion; l,2,3-Benzotriazin-4(3H)-one, 3-(Mercapto-
methyl)-, O,O-Dimethyl Phosphorodithioate; 3-(Mercaptomethyl)-1,2,3-
Benzotriazin-4(3H)-one O,O- Dimethyl Phosphorodithioate S-Ester; Bay 17147; Bay
9027; Bayer 17147; Bayer 9027; Benzotriazine Derivative of a Methyl
Dithiophosphate; Benzotriazinedithiophosphoric Acid Dimethoxy Ester; Carfene;
Cotneon; Cotnion; Cotnion Methyl; Crysthion 2L; Crysthyon; DBD;
Dimethyldithiophosphoric Acid N-Methylbenzazimide Ester; ENT 23,233; Gothnion;
Gusathion; Gusathion 25; Gusathion K; Gusathion M; Gusathion Methyl;
Gusathion-20; Guthion; Methyl Azinphos; Methyl Gusathion; Metiltriazotion;
N-Methylbenzazimide, Dimethyldithiophosphoric Acid Ester; NCI-C00066;
O,O-Dimethyl S-(3,4-Dihydro-4-Keto-l,2,3-Benzotriazinyl-3-Methyl)
Dithiophosphate; O,O-Dimethyl S-(4-Oxo-l,2,3-Benzotriazino(3)-Methyl)
Thiothionophosphate; O,O-Dimethyl S-(4-Oxo-3H-l,2,3-Benzotriazine-3-Methyl)
Phosphorodithioate; O,O-Dimethyl S-(4-Oxobenzotriazino-3-Methyl)
Phosphorodithioate; O,O-Dimethyl S-4-Oxo-l,2,3-Benzotriazin-3(4H)-ylmethyl
Phosphorodithioate; O,O-Dimethyl-S-(l,2,3-Benzotriazinyl-4-Keto)Methyl
Phosphorodithioate; O,O-Dimethyl-S-(Benzaziminomethyl) Dithiophosphate;
Phosphorodithioic Acid, O,O-Dimethyl Ester, S-Ester With 3-(Mercaptomethyl)-
l,2,3-Benzotriazin-4(3H)-one; Phosphorodithioic Acid, O,O-Dimethyl S-((4-Oxo-
l,2,3-Benzotriazin-3(4H)-yl)Methyl) Ester; Phosphorodithioic Acid, O,O-
Dimethyl S-(4-Oxo-l,2,3-Benzotriazin-3(4H)-ylmethyl)Ester; R 1582;
S-(3,4-Dihydro-4-Oxo-l,2,3-Benzotriazin-3-ylmethyl) O,O-Dimethyl
Phosphorodithioate; S-(3,4-Dihydro-4-Oxo-Benzo(alpha)-(l,2,3-Triazin-3-yl
Methyl) O,O-Dimethyl Phosphorodithioate
Chemical Formula: C10H12N3O3PS2
Molecular Weight: 317.34
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.069 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
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CAS Registry Number: 86-50-0
Page 2 of 4
AZINPHOS-METHYL
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.44 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): Negligible at 20°C (*Worthing 1979)
Melting Point: 163-165°F; 73-74°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 33 ppm at room temperature (*Worthing 1979)
Appearance and Odor: White crystals (*Worthing 1979) or brown waxy solid
(*Hawley 1981)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.2 mg/m3 (NIOSH 1987, p.54)
ACGIH TLV: TWA 0.2 mg/m3 (ACGIH 1986-87, p. 10)
IDLH: 5 mg/m3 (NIOSH 1987, p.54)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hayes 1982, p. 358)
Skin: Yes (Hayes 1982, p. 358)
Ingestion: Yes (Hayes 1982, p. 358)
Health Hazards (Acute, Delayed, and Chronic): Acute: extremely toxic.
Probable oral lethal dose in humans is 5-50 mg/kg, or between 7 drops and 1
teaspoon for a 70 kg (150 Ib.) person. A potent ch'olinesterase inhibitor
which can cause death (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (*DOT 1984).
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CAS Registry Number: 86-50-0
Page 3 of 4
AZINPHOS-METHYL
SECTION IV (continued)
Special Fire Fighting Procedures: Move containers from fire area if you
can do it without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (*DOT 1984).
Unusual Fire and Explosion Hazards: Some of the formulations may burn,
but none of them ignite easily. Container may explode in the heat of the
fire (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Unstable at temperatures above 390°F (200°C)
(*Worthing 1979)
Stable:
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Rapidly hydrolyzed by cold alkali
or cold acid (*Worthing 1979)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide for control of pests on a wide range of crops. Used to control
boll weevil on cotton, and for control of insects on deciduous fruits,
nuts, vegetables, field crops, citrus, and for non-agricultural use (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site (*DOT
1984). Do not touch spilled material. Stop leak if you can do so without
risk. Use water spray to reduce vapors. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (*DOT 1984).
-------
CAS Registry Number: 86-50-0
Page 4 of 4
AZINPHOS-METHYL
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 86-50-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
AZINPHOS-METHYL
(86-50-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystals.
Commercial Forms - Waxy brown solid, 50% wettable powder or water emulsion.
Use - Insecticide.
Other Names - l,2,3-Benzotriazin-4(3H)-one, 3-(mercaptomethyl)-, O,O-dimethyl
phosphorodithioate; Carfene; Cotneon; Cotnion-Methyl; Crysthyon; Gusathion M;
Guthion.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Azinphos-Methyl Exposure:
Warning: Effects may be delayed up to 12 hours. Caution is advised.
Note: Azinphos-methyl is a cholinesterase inhibitor.
Acute exposure to azinphos-methyl may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Chest pain may be noted. Hypotension (low blood
pressure) may be observed, although hypertension (high blood pressure) is not
uncommon. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
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CAS Registry Number: 86-50-0
Page 2 of 3
AZINPHOS-METHYL
Emergency Life-Support Procedures:
Acute exposure to azinphos-methyl may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to azinphos-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to azinphos-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas three times with soap and water.,
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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CAS Registry Number: 86-50-0
Page 3 of 3
AZINPHOS-METHYL
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of azinphos-methyl is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of azinphos-methyl may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 86-88-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ANTU
CAS Registry Number: 86-88-4
Synonyms: Urea, l-(l-Naphthyl)-2-Thio-; alpha-Naphthylthiourea;
l-(l-Naphthyl)-2-Thiourea; l-(l-Naphthyl)Thiourea; 1-Naphthyl Thiourea;
1-Naphthylthiourea; alpha-Naphthothiourea; alpha-Naphthylthiocarbamide;
alphanaphthyl Thiourea; Alrato; Anturat; Bantu; Chemical 109; Dirax; Kill
Kantz; Kripid; Krysid; Krysid PI; N-(l-Naphthyl)-2-Thiourea;
N-1-Naphthylthiourea; Naphtox; Rat-Tu; Rattrack; Smeesana; Thiourea,
1-NaphthalenyI-; U-5227; USAF EK-P-5976
Chemical Formula: CnH10N2S
Molecular Weight: 202.23
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (dog)
0.38 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0 at 25°C (*Sax 1975)
Melting Point: 388°F, 198°C (*Merck 1976)
Vapor Density (AIR=1): 6.99 (*NIH EPA, OHM/TADS 1984)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.6 g/L water at 25°C (*Merck 1976)
-------
CAS Registry Number: 86-88-4
Page 2 of 3
ANTU
*
SECTION II (continued)
Appearance and Odor: White crystal or powder; technical product is gray
powder (*Clarke 1981). No odor (*ACGIH 1980); bitter taste (*Merck 1976).
i
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.3 mg/m8 (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.3 mg/ms (ACGIH 1986-87, p.10)
IDLH: 100 mg/ms (*NIH EPA, OHM/TADS 1984)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Moderately toxic: probable
oral lethal dose (human) 0.5-5 gm/kg, or between 1 ounce and 1 pint (or 1
Ib.) for 150 Ib. person (*Gosselin 1976). Chronic sublethal exposure may
cause antithyroid activity. Can produce hyperglycemia of three times
normal in three hours (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: People with chronic
respiratory disease or liver disease may be especially at risk (*NIOSH/OSHA
1981).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): May burn but will not ignite readily (*DOT
1984)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Stay upwind, and out of low areas.
Wear self-contained breathing apparatus and full protective clothing (*DOT
1984).
Unusual Fire and Explosion Hazards: Emits toxic fumes upon decomposition
(*Sax 1975).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 86-88-4
Page 3 of 3
ANTU
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Decomposing heat (*Sax 1975)
Incompatibility (Materials to Avoid): It reacts with silver nitrate and
strong oxidizers (*Sax 1975)
Hazardous Decomposition or Byproducts: When heated it emits sulfur
dioxide, oxides of nitrogen, and carbon monoxide (*NIOSH/OSHA 1981).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material was used primarily as a rodenticide for control of adult
Norway rats. It is not produced commercially in the U.S. (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). Do not touch
spilled material, stay upwind, keep out of low areas, deny entry
(*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include seizures, pulmonary
edema and dermal irritation (*Rumack 1975 to Present). Ingestion may cause
vomiting, shortness of breath, and bluish discoloration of the skin
(*NIOSH/OSHA 1981).
Emergency and First Aid Procedures: Move victim to fresh air. Treat
pulmonary edema with positive pressure oxygen (*Rumack 1975 to Present).
Immediately flush with fresh water for at least 15 minutes in case of skin
or eye contact (*Gosselin 1976).
-------
CAS Registry Number: 144-49-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDE TY -- FLUOROACETIC ACID
CAS Registry Ni? •-: 144-49-0
Synonyms: Ace d, Fluoro-; 2-Fluoroacetic Acid; alpha-Fluoroacetic Acid;
Cymonic Acid; , uoroethanoic Acid; Gifblaar Poison; HFA; MFA;
Monofluoroacetic n
Chemical Formula: C2HSFO2
Molecular Weight: 78.04
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 0.468 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 329°F, 165°C (*Weast 1979)
Specific Gravity (H2O=1): 1.3693 at 97°F, 36°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 95.4°F, 35.2°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Weast 1983, p. 597)
Appearance and Odor: Colorless crystals (*Hawley 1977)
-------
CAS Registry Number: 144-49-0
Page 2 of 4
FLUOROACETIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.05 mg/ms (for sodium salt) (OSHA 1984, p. 663)
ACGIH TLV: TWA 0.05 mg/ms; STEL 0.15 mg/ms (for sodium salt) (*ACGIH
1980)
IDLH: Not Found
Other Limits Recommended: IDLH for sodium salt: 5 mg/ms (NIOSH/OSHA
1978, p. 166).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): This material is very
toxic; ingestion of small quantities may cause death (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Burns (*Merck 1976)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (DOT
1984, Guide 59).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear self-contained, positive pressure breathing apparatus and full
protective clothing. Move container from fire area. Cool containers that
are exposed to flames with water from the side until well after fire is out
(DOT 1984, Guide 59).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes of fluorine containing compounds (*Sax 1979).
Some of these materials may burn but none ignite readily. These materials
may ignite combustibles (wood, paper, oil, etc.) (DOT 1984, Guide 59).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Encyc Occupat Health and Safety 1971)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 144-49-0
Page 3 of 4
FLUOROACETIC ACID
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highl- xic fumes of fluorine containing compounds (*Sax 1979).
Hazardous 1 merization: May Occur: Not Found
May Not Occur: Not Found
Conditn to Avoid: Not Found
SECTION VI - " INFORMATION
Rodenticide (Hawley 1981, p. 470). The sodium salt of this material is
used as a rodent poison (*Patty 1963).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Stop leak if you can do so without risk.
Stay upwind; keep out of low areas. Use water spray to reduce vapors.
For small spills, take up with sand or other noncombustible absorbent
material and place into containers for later disposal. For large spills,
dike spill for later disposal (DOT 1984, Guide 59).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Butyl/Neoprene GOOD/LIMITED**
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PE POOR/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 144-49
Page 4 of 4
FLUOROACETIC ACID
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: The major symptoms of fluoroacetic acid
poisoning include severe epileptiform convulsions alternating with coma and
depression; death may result from asphyxia during convulsion or from
respiratory failure. Cardiac irregularities, such as ventricular
fibrillation and sudden cardiac arrest, nausea, vomiting, excessive
salivation, numbness, tingling sensations, epigastric pain, mental
apprehension, muscular twitching, low blood pressure, and blurred vision
may also occur (*Encyc Occupat Health and Safety 1971).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Remove and isolate contaminated clothing and shoes at the site. Keep
victim quiet and maintain normal body temperature (DOT 1984, Guide 59).
-------
CAS Registry Number: 149-74-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDE HTY - DICHLOROMETHYLPHENYLSILANE
CAS Registry Ni- ? ?r: 149-74-6
Synonyms: Met >henyldichlorosilane; Phenylmethyldichlorosilane; Silane,
Dichloromethylp. yl-
Chemical Formula: C7H8Cl2Si
Molecular Weight: 191.14
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(mouse) 0.2 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 401°F, 205°C (Hawley 1981, p. 688)
Specific Gravity (H2O=1): 1.19 (*Hawley 1977)
Vapor Pressure (mmHg): 1.0 at 35.7°C (Perry 1984, p. 3-54)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless liquid (*Hawley 1977)
-------
CAS Registry Number: 149-74-6
i*age 2 of 3
DICHLOROMETHYLPHENYLSILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): The chemical is toxic and
is an irritant (*Hawley 1977). Contact may cause burns to the skin and
eyes (DOT 1984, Guide 29).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 83°F (28°C) (*Hawley 1977) (SUSPECT)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray or foam. For large fires, use water spray, fog, or foam (DOT
1984, Guide 29).
Special Fire Fighting Procedures: Isolate for 1/2 mile in all directions
if tank car or truck is involved in a fire. Wear self-contained (positive
pressure) breathing apparatus with full protective clothing. Do not get
water inside container (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of chlorine-containing compounds (Sax 1984, p. 951).
Flammable/combustible material; may be ignited by heat, sparks, or flames.
Vapors may travel to a source of ignition and flash back. Container may
explode in heat of fire. Vapor explosion hazard indoors, outdoors or in
sewers. Runoff to sewer may create fire or explosion hazard. Fire may
produce irritating or poisonous gases (DOT 1984, Guide 29).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found >
-------
CAS Registry Number: 149-74-6
Page 3 of 3
DICHLOROMETHYLPHENYLSILANE
SECTION V (continued)
Incompatibility (Materials to Avoid): Reacts strongly with oxidizing
materials (*F- 'ey 1977)
Hazardous i rnposition or Byproducts: When heated to decomposition, it
emits toxic i ;s of chlorine-containing compounds (Sax 1984, p. 951).
Hazardous P .^erization: May Occur: Not Found
May Not Occur: Not Found
Conditi to A>oid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacture of silicones ("Hawley 1977); and as a chemical
intermediate for silicone fluids, resins and elastomers (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away. Stay upwind. Stay out of low areas.
Shut off ignition sources; no flares, smoking or flames in hazard
area. Do not touch spilled material; stop leak if you can do so
without risk. Use water spray to reduce vapors; do not get water
inside container. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 29).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material;
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
29).
-------
CAS Registry Number: 151-38-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHOXYETHYLMERCURIC ACETATE
CAS Registry Number: 151-38-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 657) Mercury,
(Acetato)(2-Methoxyethvi -; Acetato(2-Methoxyethyl)Mercury; Landisan; MeEHg;
MEMA; Mercuran; Mercury, Acetoxy(2-Methoxyethyl)-; Radosan; Methoxyethyl
Mercuric Acetate
(Farm Chemicals Handbook 1984, p. CHS) Panogen
Chemical Formula: C5H10HgOs
Molecular Weight: 318.74
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
16 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Sax 1984, p. 1776)
Appearance and Odor: Crystals (Sax 1984, p. 1776)
-------
CAS Registry Number: 151-38-,.
Page 2 of 4
METHOXYETHYLMERCURIC ACETATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Mercury alkyl compounds) TWA 0.01 mg/m3, as mercury; Ceiling 40
mg/ms, as mercury (NIOSH 1987, p. 152)
ACGIH TLV: (Mercury alkyl compounds) TWA 0.01 mg/ms, as mercury; STEL 30
mg/ms, as mercury (skin) (ACGIH 1986-87, p. 22)
IDLH: (Mercury alkyl compounds) 10 mg/ms, as mercury (NIOSH 1987, p. 152)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Encyc Occupat Health and Safety
1983, p. 1337)
Skin: Yes (Non-Specific — Mercury Compounds)
(Hayes 1982, pp. 15-16)
Ingestion: Yes (Encyc Occupat Health and Safety
1983, p. 1337)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic (Hawley 1981,
p. 664). Target organs are brain and central nervous system (Hayes 1982,
pp. 18-19). Inhalation can cause lung damage; ingestion can cause kidney
damage. Women of childbearing age should avoid exposure (Encyc Occupat
Health and Safety 1983, p. 1337).
Medical Conditions Generally Aggravated by Exposure: Women of
childbearing age and persons with eczema, renal or neurological disorders
should not be exposed to mercurials (Encyc Occupat Health and Safety, 1983,
p. 1337).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is an alkyl mercury pesticide (Hayes 1982, p.
20). Small fires: dry chemical, carbon dioxide, water spray, or foam.
Large fires: water spray, fog, or foam. Move container from fire area if
you can do so without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material. Fire may
produce irritating or poisonous gases. Runoff from fire control water may
give off poisonous gases. Runoff from fire control or dilution water may
cause pollution (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This* is an alkyl mercury pesticide
(Hayes 1982, p. 20). Keep unnecessary people away; isolate hazard area and
deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces
before entering them. Wear positive pressure breathing apparatus and
special protective clothing. Remove and isolate contaminated clothing at
the site. If water pollution occurs, notify appropriate authorites (DOT
1984, Guide 55).
-------
CAS Registry Number: 151-38-2
Page 3 of 4
METHOXYETHYLMERCURIC ACETATE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of mercury (Sax 1984, p. 1776). This material may burn
but does not ignite readily. Container may explode in heat of fire (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Uns^ble: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of mercury (Sax 1984, p. 1776).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used as a pesticide in seed treatment for cotton and small grains. It is
no longer approved for this use (Farm Chemicals Handbook 1984, pp.
C144-148). It exhibits high fungicidal activity against leaf stripe of
barley, stinking smut of wheat, snow mold of rye; against seedling diseases
in beets and legumes, and for dressing "seed" potatoes, bulbs, and tubers
(Buchel 1983, pp. 250-51). Not registered as a pesticide in the U.S.
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is an alkyl mercury pesticide (Hayes 1982, p. 20). Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
-------
CAS Registry Number:
Page 4 of 4
METHOXYETHYLMERCURIC ACETATE
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATIC.
Signs and Symptoms of Exposure: This is an alkyl mercu.y pesticide.
Patients complain of headache, paresthesia of tongue, lips, fingers, and
toes, a metallic taste in mouth, gastrointestinal disturbances, gas, and
diarrh.ea. Nervous system symptoms may appear first after a relatively
slight exposure or have a latency period of several weeks. These symptoms
include fine tremors of extended hands, loss of side vision, slight loss of
coordination, loss of coordination of speech, writing and gait.
Uncoordination may progress to loss of ability to control voluntary
movements. Irritability and bad temper may progress to mania. Stupor or
coma may develop. Blisters or dermatitis may be present on skin. Symptoms
persist for years even in cases of mild exposure (Hayes 1982, pp. 20-21).
Emergency and First Aid Procedures: This is an alkyl mercury pesticide
(Hayes 1982, p. 20). Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Weast 1979
ACGIH 1983
NIOSH/OSHA 1978
Weiss 1980
Merck 1983
Clayton and Clayton 1981-82
Student 1981
-------
CAS Registry Number: 151-50-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - POTASSIUM CYANIDE
CAS Registry Number: 151-50-8
Synonyms: Cyanide of Potassium; Hydrocyanic Acid, Potassium Salt; Potassium
Cyanide (KCN)
Chemical Formula: KCN
Molecular Weight: 65.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(rabbit) 5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.52 at 16°C (Weast 1978, p. B150)
Vapor Pressure (mmHg): Not Found
Melting Point: 1173°F, 634°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 2 parts cold water or 1 part boiling
water (*Merck 1976)
Appearance and Odor: White granular powder or lumps with faint odor of
bitter almonds (*Merck 1976,* Hawley 1977)
-------
CAS Registry Number: 151-50-8
Page 2 of 4
POTASSIUM CYANIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 mg/ms as cyanide (*NIOSH/RTECS 1985)
ACGIH TLV: (Cyanides) TWA 5 mg/ms as cyanide (skin) (ACGIH 1986-87, p. 14)
IDLH: 50 mg/ms (NIOSH/OSHA 1978, p. 74)
Other Limits Recommended: NIOSH Occupational Exposure Recommended Standard
-- Air Ceiling 5 mg/ms as cyanide, 10 minutes (*NIOSH/RTECS 1985)
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Merck 1976)
Ingestion: Yes (*Merck 1976)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg or less
than a taste (7 drops) for a 150 Ib. person (*Gosselin 1976). It is an eye
and skin irritant (*Grant 1974, *Encyc Occupat Health and Safety 1971)..
Poisonous in very small quantities; a taste is lethal (*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not flammable (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Water may be used on fire in an area containing
potassium cyanide (*NFPA 1978). Extinguish with dry chemical, carbon
dioxide, water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear full protective clothing (*NFPA
1978). Wear positive pressure breathing apparatus and special protective
clothing. Move container from fire area if you can do it without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Contact with acid releases highly
flammable hydrogen cyanide gas (*NFPA 1978). Moisture may cause this
material to volatilize as hydrogen cyanide (*Peer Review Committee).
NFPA Flammability Rating: 0
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 766)
Conditions to Avoid: Avoid contact with acids (see Section *V above)
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CAS Registry Number: 151-50-8
Page 3 of 4
POTASSIUM CYANIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Reacts with acids to produce
hydrogen cyanide gas (*NFPA 1978). Reacts with strong oxidizers such as
nitrates and chlorates (NIOSH/OSHA 1978, p. 74); nitrogen trichloride;
perchloryl fluoride; sodium nitrate; acids; alkaloids; chloral hydrate;
iodine (Sax 1984, p. 2273).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of cyanide and nitrogen oxides (Sax 1984, p. 2273).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Potassium cyanide is used for electroplating, steel hardening, extraction
of gold and silver from ores, manufacture of some chemicals, and fumigation
(*Encyc Occupat Health and Safety 1971).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid water. Cover spilled material with alkali or sodium thiosulfate
(*Rumack 1975 to Present). Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Do not touch spilled
material; stop leak if you can do it without risk. Use water spray to
reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place materials into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
PVC GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 151-50-8
Page 4 of 4
POTASSIUM CYANIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 151-50-8
Page 1 of 4
Emergency First Aid Treatment Guide
for
POTASSIUM CYANIDE
(151-50-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Potassium cyanide toxicity can occur via ingestion, dermal/eye
contact, or inhalation; death may occur within minutes. IMMEDIATELY begin
administering 100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Forms - White, amorphous, deliquescent lumps or crystalline mass.
Odor - Faint odor of bitter almonds.
Commercial Forms - Pure form, solution, or reagent in 25- and 100-pound drums.
Uses - Electroplating, steel hardening, gold and silver extraction, fumigation,
insecticide, chemical intermediate.
Materials to Avoid - Acids.
Caution: Avoid sources of extreme heat including fire. Potassium cyanide will
emit toxic cyanide and nitrogen oxide fumes when heated to decomposition.
Other Names - Cyanide of potassium; hydrocyanic acid, potassium salt.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulfate), sodium
bicarbonate, diazepam, phenytoin.
Signs and Symptoms of Acute Potassium Cyanide Exposure:
Warning: Effects may be delayed. Caution is advised. Vital signs should be
monitored closely. Heart palpitation may occur within minutes after exposure.
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EFATG
CAS Registry Number: 151-50-8
Page 2 of 4
POTASSIUM CYANIDE
Signs and symptoms of acute exposure to potassium cyanide may include
hypertension (high blood pressure) and tachycardia (rapid heart rate), followed
by hypotension (low blood pressure) and bradycardia (slow heart rate). Cardiac
arrhythmias and other cardiac abnormalities are common. Cyanosis (blue tint to
the skin and mucous membranes), and cherry-red or bloody mucous membranes may
appear.
Tachypnea (rapid respiratory rate) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may occur. Headache, vertigo (dizziness),
agitation, and giddiness may precede combative behavior, convulsions,
paralysis, protruding eyeballs, dilated and unreactive pupils, and coma.
Potassium cyanide is irritating to the skin, eyes, and mucous membranes.
Lacrimation (tearing) and a burning sensation of the mouth and throat are
common. Salivation, nausea, and vomiting may also occur.
Emergency Life-Support Procedures:
Acute exposure to potassium cyanide may require decontamination and life
support for the victims. All exposed persons should be transported to a health
care facility as quickly as possible. Emergency personnel should wear
protective clothing appropriate to the type and degree of contamination. Air-
purifying or supplied-air respiratory equipment should also be worn, as
necessary. Rescue vehicles should carry supplies such as plastic sheeting and
disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to potassium cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with potassium cyanide-
contaminated persons or their gastric contents can result in self-
poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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EFATG
CAS Registry Number: 151-50-8
Page 3 of 4
POTASSIUM CYANIDE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to potassium cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen ma$k. Direct oral contact with potassium cyanide-
contaminated persons or their gastric contents can result in self-
poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
•forced-oxygen mask. Direct oral contact with potassium cyanide-
contaminated persons or their gastric contents can result in self-
poisoning.
2. RUSH to a health care facility!
3. DO NOT induce vomiting. Ipecac is not recommended for ingestion of
potassium cyanide.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
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CFATG
CAS Registry Number: 151-50-8
Page 4 of 4
POTASSIUM CYANIDE
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 151-56-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHYLENEIMINE
CAS Registry Number: 151-56-4
Synonyms: (N1OSH/RTECS 1983 Synonyms, Volume 2, p. 291) Aminoethylene;
Azacyclopropane; Azirane; Aziridine; IH-Azirine, dihydro-; Dihydroazirene;
Dimethyleneimine; Dimethylenimine; El; Ethylenimine; ENT-50324, Ethylimine.
Chemical Formula: C2H5N
Molecular Weight: 43.07
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.1 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 131-133°F, 55-56°C (Clayton and Clayton 1981-82,
p. 2673)
Specific Gravity (H2O=1): 0.8321 at 20°C (Clayton and Clayton 1981-82, p.
2673)
Vapor Pressure (mmHg): 160 at 20°C (Clayton and Clayton 1981-82,
p. 2673)
Melting Point: -98°F, -72°C (Freezing Point) (Clayton and Clayton
1981-82, p. 2673)
Vapor Density (AIR=1): 1.48 (Clayton and Clayton 1981-82, p. 2673)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (Merck 1983, p. 3744)
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CAS Registry Number: 151-56-4
iage 2 of 4
ETHYLENEIMINE
SECTION II (continued)
Appearance and Odor: Colorless, mobile fluid with a strong ammoniacal
odor (Clayton and Clayton 1981-82, p. 2673; Merck 1983, p. 3744)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Occupational carcinogen; no permissible exposure limit (NIOSH
1987, Appendix C)
ACGIH TLV: TWA O.Sppm (1.0 mg/ms) (skin) (ACGIH 1986-87, p. 19)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 443)
Skin: Yes (Weiss 1980, p. 443)
Ingestion: Yes (Weiss 1980, p. 443)
Health Hazards (Acute, Delayed, and Chronic): Ethyleneimine is classified
as extremely toxic with a probable oral lethal dose of 5-50 mg/kg which is
approximately 7 drops to 1 teaspoonful for a 70 kg (150 Ib.) person
(*Gosselin 1976). Ethyleneimine gives inadequate warning when
over-exposure is by inhalation or skin absorption. It is a severe
blistering agent, causing third degree chemical burns of the skin. Also,
it has a corrosive effect on mucous membranes and may cause scarring of the
esophagus. It is corrosive to eye tissue and may cause permanent corneal
opacity and conjunctival scarring (Weiss 1980, p. 443). Severe exposure
may result in overwhelming pulmonary edema. Renal damage has been
described (Gosselin 1984, p. H-207). Hemorrhagic congestion of all
internal organs has been observed (Clayton and Clayton 1981-82, p. 2674).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 12°F (CC) (NFPA 1984, p. 325M-51)
Flammable Limits:
LEL: 3.6% (NFPA 1984, p. 325M-51)
UEL: 46% (NFPA 1984, p. 325M-51)
Extinguishing Methods: Dry chemical, alcohol foam, or carbon dioxide are
useful for small fires. For large fires: water spray, fog or foam (DOT
1984, Guide 30).
Special Fire Fighting Procedures: Do not extinguish fire unless flow can
be stopped; use water in flooding quantities as a fog. Solid streams of
water may be ineffective. Apply water from as far a distance as possible
(Student 1981, p. 236). If tank car or truck is involved in fire, isolate
the surrounding area in a 1/2 mile radius (DOT 1984, Guide 30).
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CAS Registry Number: 151-56-4
Page 3 of 4
ETHYLENEIMINE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Irritating vapors are generated when
heated. Vapor is heavier than air and may travel a considerable distance
to a source of ignition and flash back. May polymerize in fires with
evolution of heat and container rupture (Weiss 1980, p. 443). Runoff to
sewer may create fire or explosion hazard (DOT 1984, Guide 30).
Ethyleneimine vapors are not inhibited and may form polymers in vents or
flame arresters, r , alting in stopping of the vents (*NFPA 1978).
NFPA Flammabilu; Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 443)
Conditions to Avoid: If heated under pressure, instability may result
(Weiss 1980, p. 443).
Incompatibility (Materials to Avoid): Acids (Weiss 1980, p. 443); sodium
hypochlorite (*Bretherick 1979).
Hazardous Decomposition or Byproducts: Toxic oxides of nitrogen are
produced during combustion (Student 1981, p. 236). Upon treatment with
sodium hypochlorite, it gives off the explosive compound 1-chloroazidine
(*Bretherick 1979).
Hazardous Polymerization: May Occur: Yes (Merck 1983, p. 551)
May Not Occur:
Conditions to Avoid: Avoid contact with silver or aluminum.
Explosive polymerization may occur upon contact with acids (Weiss 1980,
p. 443). Polymerization is catalyzed by carbon dioxide (*Bretherick
1979).
SECTION VI - USE INFORMATION
Products of polymerization of ethyleneimine are used in the paper industry
and as flocculation aids (*Encyc Occupat Health and Safety 1971). Used in
textile chemicals, adhesives, binders, petroleum refining chemicals, fuels
and lubricants, coating resins, varnishes, lacquers, agricultural
chemicals, cosmetics, ion exchange resins, photographic chemicals and
surfactants (*Clayton and Clayton 1981-82).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors. Keep upwind. Avoid bodily contact with the
material. Do not handle broken packages without protective equipment. Wash
away any material which may have contacted the body with copious amounts of
-------
C .5 Registry Number: 151-56-4
I age 4 of 4
ETHYLENEIMINE
SECTION VII (continued)
water or soap and water (Student 1981, p. 237). ^Keep unnecessary people
away, isolate hazard area and deny entry. Stay upwind, keep out of low
areas (DOT 1984, Guide 30).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Neoprene POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include tearing and burning of
the eyes, sore throat, nausea, vomiting, coughing (may persist for weeks or
months) and a slow healing dermatitis due to severe blistering (Gosselin
1984, p. 11-207; Weiss 1980, p. 443).
Emergency and First Aid Procedures: Move victim to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. Remove and isolate contaminated clothing and shoes at the site.
In case of contact with ethyleneimine, immediately flush skin or eyes with
running water for at least 15 minutes (DOT 1984, Guide 30).
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CAS Registry Number: 152-16-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIPHOSPHORAMIDE, OCTAMETHYL-
CAS Registry Number: 152-16-9
Synonyms: Pyrophosphoramide, Octamethyl-; Bis(bisdimethylaminophosphonous)
anhydride; Bis(dimethylamino)phosphoric anhydride; Bis-N,N,N',N'-tetramethyl-
phosphorodiamidic anhydride; Lethalaire G-59; Octamethyl pyrophosphortetramide;
Octamethyl tetramido pyrophosphate; Octamethyldiphosphoramide; Octamethyl-
pyrophosphoramide; Octamethylpyrophosphoric acid tetramide; OMPA; Ompacide;
Ompatox; Ompax; Pestox III; Schradan; Pyrophosphoric acid octamethyltetraamide;
Pyrophosphoryltetrakisdimethylamide; Scharadan; Systam; Systophos; Sytam;
Tetrakisdimethylaminophosphonous anhydride
Chemical Formula: C8H24N4P2OS
Molecular Weight: 286.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral (rat)
5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 248-257°F, 120-125°C at 0.5 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.09 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 0.001 at 25°C (*Worthing 1979)
Melting Point: 57-68°F, 14-20°C (*Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1976)
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CAS Registry Number: 152-16-9
Page 2 of 4
DIPHOSPHORAMIDE, OCTAMETHYL-
SECTION II (continued)
Appearance and Odor: Viscous liquid (*Merck 1976); dark brown viscous
liquid (*Worthing 1979).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Maximum permissible atmospheric concentration
of this compound in work places is estimated to be 0.5 mg/ms (*Clarke
1975).
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and Safety
1971)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic; probable
oral lethal dose in humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful
for a 150 Ib. person (*Gosselin 1976). It is highly toxic when inhaled
(*Encyc Occupat Health and Safety 1971). Material is a cholinesterase
inhibitor (*Hayes, 1975). It is similar in action to other
organophosphorous pesticides in its toxicity. It is slightly less toxic
than parathion (*Gosselin 1976). Gastrointestinal, neurologic and
respiratory symptoms may accompany poisoning with this material. High
doses may cause a toxic psychosis similar to acute alcoholism (*Rumack 1975
to Present).
Medical Conditions Generally Aggravated by Exposure: Persons taking
phenobarbital and phenaglycodol together, glutethimide, chlorpromazine
hydrochloride, or meprobamate may be at greater risk. These drugs appear
to enhance the toxicity of the material markedly (*Kato 1967).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Liquid
Pesticides) Do not extinguish fire unless flow can be stopped. Use water
in flooding quantities as fog. Solid streams of water may be ineffective.
Cool all affected containers with flooding quantities of water. Apply
water from as far a distance as possible. Use alcohol foam, carbon
dioxide, or dry chemical (*Student 1981).
Special Fire Fighting Procedures: Not Found
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CAS Registry Number: 152-16-9
Page 3 of 4
DIPHOSPHORAMIDE, OCTAMETHYL-
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, it can
emit highly toxic fumes of oxides of phosphorus (*Sax 1979).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Hydrolyzed under acid conditions to
dimethylamine and orthophosphoric acid (*Worthing 1979)
Incompatibility (Materials to Avoid): Decomposes when mixed with acid
(*Worthing 1979).
Hazardous Decomposition or Byproducts: Decomposes when mixed with acid
(*Worthing 1979). Emits highly toxic fumes of oxides of phosphorous when
heated to decomposition (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Material is used as a systemic insecticide for plants and as an acaricide
(*Merck 1976). Not registered as a pesticide in the U.S. (USEPA/Pesticide
Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Liquid Pesticides) Use water spray to
knock down vapors. Attempt to stop leak if it can be done without hazard.
Avoid breathing vapors. Keep upwind. Avoid bodily contact with material.
Do not handle broken packages without protective equipment.
Wash away any material which may have contacted the body with copious
amounts of water or soap and water (*Student 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 152-16-9
Page 4 of 4
DIPHOSPHORAMIDE, OCTAMETHYL-
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 152-16-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIPHOSPHORAMIDE, OCTAMETHYL-
(152-16-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Viscous liquid.
Commercial Form - Dark brown viscous liquid (technical grade).
Use - Pesticide.
Caution: Avoid sources of extreme heat including fire. Di phosphor amide,
octamethyl- will liberate toxic phosphorus oxides when heated to
decomposition.
Other Names - OMPA, Omapacide, Ompatox, Ompax, Pestox III, Schradan, Systam,
Systophos, Sytam.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Diphosphoramide, Octamethyl- [OMPA] Exposure:
Note: Octamethyl diphosphoramide is a cholinesterase inhibitor.
Acute exposure to OMPA may produce the following signs and symptoms: pinpoint
pupils, blurred vision, headache, dizziness, muscle spasms, and profound
weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may also
occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) and chest pain may
be noted. Hypertension (high blood pressure) is not uncommon. Respiratory
symptoms include dyspnea, respiratory depression, and respiratory paralysis.
Psychosis may occur.
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EFATG
CAS Registry Number: 152-16-9
Page 2 of 3
DIPHOSPHORAMIDE, OCTAMETHYL-
Emergency Life-Support Procedures:
Acute exposure to OMPA may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to OMPA.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to OMPA.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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CAS Registry Number: 152-16-9
Page 3 of 3
DIPHOSPHORAMIDE, OCTAMETHYL-
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of OMPA is unknown or suspected to be greater than 30 minutes,
do not induce vomiting and proceed to Step 4. Ipecac should not be
administered to children under 6 months of age.
Warning: Ingestion of OMPA may result in sudden onset of seizures or loss
of consciousness. Syrup of Ipecac should be administered only if victims
are alert, have an active gag-reflex, and show no signs of impending
seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 297-78-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ISOBENZAN
CAS Registry Number: 297-78-9
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 697)
4,7-Methanoisobenzofuran, l,3,4,5,6,7,8,8-Octachloro-l,3,3a,4,7,7a-Hexahydro-;
CP 14,957; ENT 25,545; ENT 25,545-X; l,3,4,5,6,7,8,8-Octachloro-l,3,3a,4,7,7a-
hexahydro-4,7-methanoisobenzofuran; 1,3,4,5,6,7,8,8-Octachloro-2-oxa-3a,4,7,7a-
tetrahydro-4,7-methanoindene; 1,3,4,5,6,7,10,10-Octachloro-4,7-endo-methylene-
4,7,8,9-tetrahydrophthalan; Omtan; SD 4402; Shell 4402; Shell WL 1650;
Telodrin; WL 1650
Chemical Formula: C9H4C18O
Molecular Weight: 411.73
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (dog)
1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.87 (Hayes 1982, p. 251)'
Vapor Pressure (mmHg): 0.00001 at 77°F, 25°C (Hayes 1982, p. 251)
Melting Point: 248-252°F, 120-122°C (Merck 1983, pp. 738-739)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Hayes 1982, p. 251)
-------
CAS Registry Number: 297-78-9
Page 2 of 4
ISOBENZAN
SECTION II (continued)
Appearance and Odor: Crystals (Merck 1983, pp. 738-739). The technical
product is a whitish to light-brown crystalline powder with a mild chemical
odor (Hayes 1982, p. 251)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hayes 1982, p. 251)
Skin: Yes (Hayes 1982, p. 251)
Ingestion: Yes (Hayes 1982, p. 251)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic. It is absorbed by the skin as well as by the respiratory and
gastrointestinal tract. Symptoms may last for a long time because the
material is eliminated slowly; its half-life in human blood is 2.77 years
(Hayes 1982, p. 251).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Non-flammable and non-explosive (Hayes 1982, p. 251)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Dry Insecticide) Use agent
suitable for type of surrounding fire. Use water in flooding quantities as
fog. Use alcohol foam, carbon dioxide, or dry chemical (Student 1981, p.
290).
Special Fire Fighting Procedures: (Non-Specific — Dry Insecticide)
Avoid breathing dusts and fumes from burning material. Keep upwind. Avoid
bodily contact with the material. Wear full protective clothing including
boots, protective gloves, goggles, and wear self-contained breathing
apparatus (Student 1981, p.290).
Unusual Fire and Explosion Hazards: Chlorine is evolved when this
material is heated above 410°F, 210°C (Hayes 1982, 251).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 297-78-9
Page 3 of 4
ISOBENZAN
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Acids, certain metal salts, and
catalytically active carriers (Hayes 1982, p. 251)
Hazardous Decomposition or Byproducts: Chlorine is evolved if material is
heated above 410°F, 210°C (Hayes 1982, p. 251).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide (Merck 1983, pp. 738-739). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Dry Insecticide) Keep upwind. Avoid bodily contact with
the material (Student 1981, p. 290).
(Non-Specific -- Insecticide, Dry, n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Small spills: absorb with
sand or other noncombustible absorbent material and place into containers
for later disposal. Small dry spills: with clean shovel place material
into clean, dry container and cover; move containers from spill area.
Large spills: dike far ahead of spill for later disposal (DOT 1984, Guide
53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED**
Butyl/Neoprene POOR/LIMITED**
PVC POOR/LIMITED**
-------
-S Registry Number: 297-78-9
1 v.ge 4 of 4
ISOBENZAN
SECTION VIII (continued)
Viton POOR/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of exposure include headache,
dizziness, drowsiness, irritability, and numbness of the legs. Convulsions
may occur (Hayes 1982, p. 251).
Emergency and First Aid Procedures: (Non-Specific -- Insecticide, Dry,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 297-97-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THIONAZIN
CAS Registry Number: 297-97-2
Synonyms: Phosphorothioic Acid, O,O-Diethyl O-Pyrazinyl Ester; AC 18133; ACC
18133; American Cyanamid 18133; CL 18133; Cynem; O,O-Diethyl O-2-Pyrazinyl
Phosphorothioate; Diethyl O-2-Pyrazinyl Phosphorothionate; O,O-Diethyl
O-2-Pyrazinyl Phosphothionate; O,0-Diethyl O-Pyrazinyl Thiophosphate; EN 18133;
ENT 26,680; Ethyl Pyrazinyl Phosphorothioate; Experimental Nematocide 18,133;
Nemafos; Nemaphos; Nematocide; Phosphorothioic Acid, O,O-Diethyl O-2-Pyrazinyl
Ester; Pyrazinol, O-Ester with O,O-Diethyl Phosphorothioate; Zinophos
Chemical Formula: C8H1SN2O3PS
Molecular Weight: 248.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
3.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II « PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 176°F, 80°C at 0.001 mmHg (Hawley 1981, p. 1019)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.003 at 30°C (Merck 1983, p. 1338)
Melting Point: 29°F, -1.7°C (Hawley 1981, p. 1019)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Hawley 1981, p. 1019), 1140 ppm at
24.8°C (*Spencer 1982)
-------
CAS Registry Number: 297-97-2
! age 2 of 4
THIONAZIN
SECTION II (continued)
Appearance and Odor: Amber liquid (Hawley 1981, p. 1019); pure compound
is almost colorless liquid and technical product is light brown to tan
mobile liquid (*Spencer 1982)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 1019)
Skin: Yes (Hawley 1981, p. 1019)
Ingestion: Yes (Hawley 1981, p. 1019)
Health Hazards (Acute, Delayed, and Chronic): Cholinesterase inhibitor
(Hawley 1981, p. 1019). (Non-Specific — Organic Phosphate Compound,
Liquid, Poison B). Poisonous; may be fatal if inhaled, swallowed or
absorbed through skin. Contact may cause burns to skin and eyes (DOT 1984,
Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific ~ Organic Phosphate Compound,
Liquid, Poison B). Extinguish with dry chemical, carbon dioxide, water
spray, or foam. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
(Non-Specific -- Parathion) Extinguish fire using agent suitable for type
of surrounding fire. Use water in flooding quantities as fog. Use foam,
carbon dioxide, or dry chemicals (Student 1981, p. 392).
Special Fire Fighting Procedures: (Non-Specific — Organic Phosphate
Compound, Liquid, Poison B). Keep unnecessary people away; stay upwind;
wear positive pressure breathing apparatus and special protective clothing;
remove and isolate contaminated clothing (DOT 1984, Guide 55).
(Non-Specific -- Organic Phosphate Mixture, Liquid, Poison B). Do not
extinguish fire unless flow can be stopped (Student 1981, p. 392).
(Non-Specific -- Parathion) Avoid breathing dusts, and fumes from burning
materials. Avoid body contact with materials. Wear full protective
clothing (Student 1981, p. 392).
-------
CAS Registry Number: 297-97-2
Page 3 of 4
THIONAZIN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Organic Phosphate
Compound, Liquid, Poison B). This material may burn but does not ignite
readily (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: (Non-Specific -- Organic Phosphate
Compound, Liquid, Poison B). Fire may produce irritating or poisonous
gases (DOT 1984, Guide 55).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
It is used in insecticides, fungicides, and nematocides (Hawley 1981, p.
1019). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organic Phosphate Compound, Liquid, Poison B). Do not
touch spilled material; stop leak if possible; use water spray to reduce
vapors. Small spill: take up with sand or other noncombustible absorbent
material and place into container for later disposal. Large spills: dike
far ahead of spill for later disposal (DOT 1984, Guide 55). (Non-Specific
~ Parathion) Avoid breathing vapors. Avoid bodily contact with
materials. Do not handle broken packages without protective equipment.
Wash away any material which may have contacted the body with copious
amounts of water or soap and water (Student 1981, p. 392).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
-------
CAS Registry Number: 297-97-2
Page 4 of 4
THIONAZIN
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Parathion). Acute
effects include loss of appetite, nausea, vomiting, diarrhea, excessive
salivation, pupillary constriction, bronchoconstriction, muscle twitching,
convulsions, and coma (Merck 1983, p. 1010).
Emergency and First Aid Procedures: (Non-Specific -- Organic Phosphate
Compound, Liquid, Poison B). Move victim to fresh air; call emergency
medical care. If not breathing give artificial respiration; if breathing
is difficult give oxygen. "In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes; speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site (DOT 1984, Guide 55).
(Non-Specific -- Organic Phosphate Mixture, Liquid, Poison B). Wash away
any material which may have contacted the body with copious amounts of
water or soap and water (Student 1981, p. 381).
COMMENTS:
Sources searched and no information found:
Hayes 1982
Weast 1979
Sax 1984
Clayton and Clayton 1981-82
NFPA 1984
NIOSH/OSHA 1978
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CAS Registry Number: 298-00-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PARATHION-METHYL
CAS Registry Number: 298-00-0
Synonyms: Phosphorothioic Acid, O,O-Dimethyl O-(p-Nitrophenyl) Ester (Dry
Mixture); Methyl Parathion; Azofos; Azophos; BAY 11405; Bladan-M; Dalf;
Dimethylfenitrothion; Dimethyl 4-Nitrophenyl Phosphorothionate; Dimethyl
p-Nitrophenyl Phosphorothionate; Dimethyl p-Nitrophenyl Thiophosphate; Dimethyl
Parathion; E 601; ENT 17,292; Folidol M; Folidol M-40; Gearphos; M-Parathion;
Meptox; Metacid 50; Metacide; Metafos; Metafos (Pesticide); Metaphos; Methyl-E
605; Methylthiophos; Metron; Metron (Pesticide); NCI-C02971; Nitrox; Nitrox 80;
O,O-Dimethyl O-(p-Nitrophenyl) Phosphorothioate; O,O-Dimethyl O-(p-Nitrophenyl)
Thionophosphate; O,O-Dimethyl O-(p-Nitrophenyl) Thiophosphate; Oleovofotox;
Parathion Methyl Homolog; Partron M; Penncap M; Penncap MLS; Phenol, p-Nitro-,
O-Ester with O,O-Dimethyl Phosphorothioate; Phosphorothioic Acid, O,O-Dimethyl
O-(4-Nitrophenyl) Ester; Quinophos; Sinafid M-48; Thiophenit; Vofatox; Wofatox;
Wofotox; 8056 HC
Chemical Formula: C8H10NO5PS
Molecular Weight: 263.23
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.034 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.358 at 20°C (*Merck 1983)
Vapor Pressure (mmHg): 0.0000097 at 20°C (*Worthing 1979)
Melting Point: 99-100°F, 37-38°C (*Merck 1983)
-------
CAS Registry Number: 298-00-0
Page 2 of 4
PARATHION-METHYL
SECTION II (continue:;)
Vapor Density (Air.=l): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 50 mg/liter (*Merck 1983)
Appearance and Odor: White crystalline solid or powder (*NFPA 1978); odor
like rotten eggs or garlic ("CHRIS 1978). Commercial product is a liquid
consisting of 80 percent methyl parathion and 20 percent xylene (NFPA 1984,
pp. 49-64); light to dark tan ("Worthing 1979).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.2 mg/m8 (skin) (ACGIH 1986-7, p.24)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose is 5-50 mg/kg, or between 7 drops and
1 teaspoonful for a 150-lb. person (*Gosselin 1984). Chronic toxicity does
not appear to be a major consideration (*NRC 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not flammable at normal temperatures ("Clayton
and Clayton 1982); commercial product, containing xylene, has flashpoint of
115°F (OC) (NFPA 1984, pp. 49-64).
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (*DOT
1984).
Special Fire Fighting Procedures: Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material ("DOT
1984). Wear special protective clothing ("NFPA 1978).
Unusual Fire and Explosion Hazards: Poisonous gases are produced in fire
and when heated ("CHRIS 1978). Decomposition may lead to sufficient
-------
CAS Registry Number: 298-00-0
Page 3 of 4
PARATHION-METHYL
SECTION IV (continued)
internal pressure to cause the container to rupture violently (NFPA 1984,
pp. 49-64).
NFPA Flammability Rating: 1 (solid); 3 (xylene solution)
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: High temperatures (120°F) cause decomposition
(NFPA 1984, pp. 49-64).
Incompatibility (Materials to Avoid): Oxidizing materials (NFPA 1984, pp.
49-64).
Hazardous Decomposition or Byproducts: Decomposition may lead to rupture
of containers (NFPA 1984, pp. 49-64).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide on over 50 crops, primarily cotton,
and on several ornamentals (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other non-combustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry containers and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
C \S Registry Number: 298-00-0
I age 4 of 4
PARATHION-METHYL
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 298-00-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
PARATHION-METHYL
(298-00-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White crystalline solid or powder.
Odor - Resembling rotten eggs or garlic.
Commercial Forms - Emulsifiable concentrates, wettable powders, dusts, or light
to dark tan liquid consisting of 80% parathion-methyl and 20% xylene.
Use - Insecticide.
Materials to Avoid - Oxidizers.
Other Names - Dalf; Dimethyl parathion; ENT-17,292; Folidol-M; Meptox;
Metacide; Metaphos; Metron; Nitrox; Partron M; Penncap M; phosphorothioic acid,
O,O-dimethyl O-(p-nitrophenyl)ester; Quinophos; Thiophenit; Vofatox; Wofatox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Parathion-Methyl Exposure:
Note: Parathion-methyl is a cholinesterase inhibitor.
Acute exposure to parathion-methyl may produce the following signs and
symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms,
and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma
may also occur.
The heart rate may decrease following oral exposure or increase following
dermal exposure. Hypotension (low blood pressure) may occur although
hypertension (high blood pressure) is not uncommon. Chest pain may be noted.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
-------
i-FATG
CAS Registry Number: 298-00-0
Page 2 of 3
PARATHION-METHYL
Emergency Life-Support Procedures:
Acute exposure to parathion-methyl may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to parathion-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to parathion-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 298-00-0
Page 3 of 3
PARATHION-METHYL
Ingestion Exposure:
J. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of parathion-methyl is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of parathion-methyl may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 298-02-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHORATE
CAS Registry Number: 298-02-2
Synonyms: Phosphorodithioic Acid, O,O-Diethyl S-(EthyIthio)MethyI Ester;
Methanethiol, (Ethylthio)-, S-Ester with O,O-Diethylphosphorodithioate;
O,O-Diethyl S-Ethylmercaptomethyl Dithiophosphonate; O,O-Diethyl
S-Ethylthiomethyl Dithiophosphonate; O,O-Diethyl S-(Ethylthio)methyl
Dithiophosphonate; Experimental Insecticide 3911; L 11/6; Thimet; American
Cyanamid 3,911; AC 3911; American Cyanamid 3911; El 3911; ENT 24,042, ENT
24042; Granutox; O,O-Diethyl Ethylthiomethyl Phosphorodithioate; O,O-Diethyl
S-Ethylmercaptomethyl Dithiophosphate; O,O-Diethyl S-Ethylthiomethyl
Thiothionophosphate; Phorate 10G; Rampart; Thimet 10G; Timet; Vegfru; Vergfru
Foratox; VUAgT 182
Chemical Formula: C7H17O2PS3
Molecular Weight: 260.39
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.011 mg/liter for 1 hour (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 257-261°F, 125-127°C at 2 mmHg (*Merck 1983)
Specific Gravity (H2O=1): 1.156 at 25°C (*Merck 1983)
Vapor Pressure (mmHg): 0.00084 at 20°C (*Merck 1983)
Melting Point: -45°F, -42.9°C (*Spencer 1982)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 298-02-2
Page 2 of 4
PHORATE
SECTION II (continued)
Solubility in Water: 50 mg/liter (*Merck 1983)
Appearance and Odor: Clear liquid (*Merck 1983); objectionable odor
(*Osol 1980)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.05 mg/ms (skin); STEL 0.2 mg/ms (skin) (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*ACGIH 1980)
Skin: Yes (*ACGIH 1980)
Ingestion: Yes (*ACGIH 1980)
Health Hazards (Acute, Delayed, and Chronic): This material is one of the
more toxic organophosphorus insecticides (*Osol 1980). It is a
cholinesterase inhibitor that acts on the nervous system, and produces
toxicity similar to Parathion. The probable oral lethal dose for humans is
less than 5 mg/kg, i.e. a taste (less than 7 drops) for a 70 kg (150 Ib.)
person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Orgahophosphorous Pesticide)
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 55)
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorous
Pesticide) Wear positive pressure self-contained breathing apparatus.
Move container from fire area if you can do it without risk. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Shock can shatter containers,
releasing the contents. When heated to decomposition, toxic fumes of
sulfur oxides, phosphorus oxides, and nitrogen oyi:; ^ emitted (Sax
1984, p. 2208).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 298-02-2
Page 3 of 4
PHORATE
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1983)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzed in water and alkalies
(*Merck 1983).
Hazardous Decomposition or Byproducts: When heated to decomposition,
sulfur oxides, phosphorus oxides, and nitrogen oxides are emitted (Sax
1984, p. 2208)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material is used as an insecticide and acaricide; it is applied to
plants and soil (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical aftalog.
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CAS Registry Number: 298-02-2
Page 4 of 4
PRORATE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 298-02-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
PRORATE
(298-02-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Clear liquid.
Odor - Objectionable.
Commercial Forms - 2.5, 5, 10, and 20% pure granules.
Use - Pesticide.
Caution: Phorate will form toxic mixtures of sulfur oxides, phosphorus oxides,
and nitrogen oxides when heated to decomposition. Avoid sources of extreme
heat.
Other Names - American Cyanamid 3911, Granutox, Rampart, Thimenox, Thimet,
Vegfru, O,O-diethyl S-ethylmercaptomethyl dithiophosphonate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Phorate Exposure:
Note: Phorate is a cholinesterase inhibitor.
Acute exposure to phorate may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
The heart rate may decrease following oral exposure or increase following
dermal exposure. Chest pain may be noted. Hypotension (low blood pressure)
may occur, although hypertension (high blood pressure) is not uncommon.
Dyspnea (shortness of breath) may be followed by respiratory collapse.
Giddiness is common.
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EFATG
CAS Registry Number: 298-02-2
Page 2 of 3
PRORATE
Emergency Life-Support Procedures:
Acute exposure to phorate may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phorate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phorate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5, Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 298-02-2
Page 3 of 3
PHORATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of phorate is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of phorate may result in .sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 298-04-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DISULFOTON
CAS Registry Number: 298-04-4
Synonyms: Phosphorodithioic Acid, O,O-Diethyl S-(2-(Ethylthio)Ethyl) Ester;
Bay 19639; Bayer 19639; Di-syston; Di-syston G; Dimaz; Disulfaton; Disystox;
Dithiodemeton; Dithiosystox; Dution; Ekatin TD; ENT 23,437; ENT-23437; Ethyl
Thiometon; Ethylthiometon B; Frumin; Frumin AL; Frumin G; Glebofos; M 74
(Pesticide); M-74; 0,O-Diethyl 2-Ethylthioethyl Phosphorodithioate; O,O-Diethyl
S-(2-(Ethylthio)Ethyl) Phosphorodithioate; O,O-Diethyl S-(2-Eththioethyl)
Phosphorodithioate; O,O-Diethyl S-(2-Eththioethyl)Thiothionophosphate;
O,O-Diethyl S-(2-Ethylmercaptoethyl) Dithiophosphate; O,O-Diethyl
S-2-(Ethylthio)Ethyl Phosphorodithioate; O,O-Ethyl S-2(Ethylthio)Ethyl
Phosphorodithioate; Phosphorodithioic Acid, O,O-Diethyl S-(2-(Ethylthio)Ethyl)
Ester; Phosphorodithionic Acid, S-2-(Ethylthio)Ethyl O,O-Diethyl Ester; S 276;
S-2-(Ethylthio)Ethyl O,O-DiethyI Ester of Phosphorodithioic Acid; Solvirex;
Thiodemeton; Thiodemetron; Vuagt 1-4; Vuagt 1964
Chemical Formula: C8H19O2PS3
Molecular Weight: 274.38
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDBO oral
(rat) 2 mg/kg (*NIOSH/RTECS 1985).
TPQ: 500 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 270-271°F, 132-133°C at 1.5 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.144 (*Merck 1976)
Vapor Pressure (mmHg): 0.00018 at 20°C (*Spencer 1973)
Melting Point: Greater than -13°F, -25°C (*Sunshine 1969)
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>S Registry Number: 298-04-4
ge 2 of 4
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 25 mg/liter at 23°C (*NRC 1977)
Appearance and Odor: Oily, colorless liquid when pure; technical product
is dark yellowish oil (*Spencer 1973). It has a characteristic sulfur odor
(*Sax 1975).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/ms (ACGIH 1986-7, p.18)
IDLH: Not Found
Other Limits Recommended: An airborne limit of 0.1 mg/ms should serve to
limit general room contamination (* ACGIH 1980).
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste
(less than 7 drops) for a 70 kg (150 Ib.) person (*Gosselin 1976). It is
poisonous and may be fatal if inhaled, swallowed, or absorbed through the
skin. Contact may cause burns to skin and eyes (*DOT 1984).
Medical Conditions Generally Aggravated by Exposure: Not found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material. Wear
positive pressure breathing apparatus and special protective clothing (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: Material nu but does not ignite
easily. Cylinder may explode in the heat of fire ~ous gases may be
generated from the fire or runoff water (DOT I •„ ide 55).
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CAS Registry Number: 298-04-4
Page 3 of 4
DISULFOTON
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Oxidizable in air (*Sunshine 1969).
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated poisonous gases may be
given off (DOT 1984, Guide 55).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Major uses include insecticide for mites and aphids on small grains, corn,
sorghum, cotton, and other field crops, fruits, nuts, and ornamentals
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spill material. Exposure by skin contact is likely to be more
significant than inhalation (*ACGIH 1980). Small spills: take up with
sand or other noncombustible absorbent materials and place into containers
for later disposal. Large spills: dike far ahead of spill for later
disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 298-04-4
Page 4 of 4
DISULFOTuN
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 298-04-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
DISULFOTON
(298-04-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Oily brown, yellow, or colorless liquid.
Odor - Pure compound has characteristic sulfur .odor, commercial form has
aromatic odor.
Commercial Forms - Granules, powder, emulsifiable concentrate, dark yellow oil.
Use - Pesticide.
Caution: Containers may explode when exposed to high temperatures. Toxic
gases may be liberated. Avoid sources of extreme heat.
Other Names - Di-syston, disystox, Dithiosystox, Dution, Frumin, Glebofos,
Solvirex, Thiodemeton, O,O-diethyl S-2-(ethylthio)ethyl phosphorodithioate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Disulfoton Exposure:
Note: Disulfoton is a cholinesterase inhibitor.
Acute exposure to disulfoton may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
The heart rate may decrease following oral exposure or increase following
dermal exposure. Hypotension (low blood pressure) and chest pain may be noted.
Hypertension (high blood pressure) is not uncommon. Respiratory symptoms
include dyspnea (shortness of breath), respiratory depression, and respiratory
paralysis. Psychosis may occur.
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CAS Registry Number: 298-04-4
Page 2 of 3
DISULFOTON
Emergency Life-Support Procedures:
Acute exposure to disulfoton may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to disulfoton.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to disulfoton.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 298-04-4
Page 3 of 3
DISULFOTON
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of disulfoton is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of disulfoton may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 300-62-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- AMPHETAMINE
CAS Registry Number: 300-62-9
Synonyms: Phenethylamine, alpha-Methyl; (+-)-alpha-Methylbenzene- ethanamine;
(+-)-alpha-Methyl Phenethylamine; (+-)-alpha-Methylphenyl ethylamine;
(+-)-beta-Phenylisopropylamine; (+-)-Desoxynorephedrine;
(Phenylisopropyl)amine; l-Phenyl-2-aminopropane; Acetedron; Adipan; Allodene;
Anorexide; Anorexine; Benzebar; Benzedrine; Benzeneethanamine, alpha-Methyl-,
(+-); Benzolone; beta-Aminopropylbenzene; DL-l-Phenyl-2-Aminopropane;
DL-alpha-Methylphenethylamine; DL-Amphetamine; DL-Benzedrine; Elastonon; Finam;
Isoamyne; Isomyn; Mecodrin; Norephedrane; Norephedrine, deoxy-; Novydrine;
Oktedrin; Ortedrine; Percomon; Phenedrine; Profamina; Propisamine; Psychedrine;
Racemic desoxy-nor-ephedrine; Raphetamine; Rhinalator; Simpatedrin; Simpatina;
Sympamine; Sympatedrine; Weckamine
Chemical Formula: C9H1SN
Molecular Weight: 135.20
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 22mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 392-397°F, 200-203°C (*Merck 1976)
Specific Gravity (H2O=1): 0.913 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 4.65 (Sax 1984, p. 271)
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CAS Registry Number: 300-62-9
Page 2 of 4
AMPHETAMINE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Evaporates slowly at room temperature
(*Merck 1976).
Solubility in Water: Slightly soluble (*Merck 1976).
Appearance and Odor: Colored liquid; amine odor (*Merck 1976).
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Not Found
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely hazardous. Probable lethal dose in humans is 5-50 mg/kg or 7
drops to 1 teaspoon for a 70 kg (150 Ib.) person (*Gosselin 1976). Habit
forming drug which affects the central nervous system (Hawley 1981, p. 65).
Medical Conditions Generally Aggravated by Exposure: Excessive use may
lead to tolerance and physical dependence (*Merck 1976). Death is possible
(Gosselin 1976, p. 11-369).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 80°F, 26.6°C (no method given) (Hawley 1981,
p. 65)
Flammable Limits: It is flammable (Hawley 1981, p. 65)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with carbon dioxide or dry chemical
(*Sax 1975).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Dangerous when exposed to heat or
flames (*Sax 1975).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 300-62-9
Page 3 of 4
AMPHETAMINE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Can react with oxidizing materials
(*Sax 1975).
Hazardous Decomposition or Byproducts: Upon decomposition, nitrogen
oxides are emitted (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Amphetamine is used as a pharmaceutical (Hawley 1981, p. 65). It is a
central nervous system stimulant (*Rossoff 1974).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Drugs, n.o.s.) Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas.
Shut off ignition sources; no flares, smoking or flames in hazard
area. Keep combustibles (wood, paper, oil, etc.) away from spilled
material. Do not touch spilled material. Small spills: absorb with
sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 11).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Nitrile GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 300-62-9
Page 4 of 4
AMPHETAMINE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Dry mouth, metallic taste, loss of
appetite, nausea, vomiting, diarrhea, abdominal cramps, headache,
chilliness, flushing or pallor, palpitation, restlessness, dizziness,
tremor, hyperactive reflexes, talkativeness, tenseness, irritability,
weakness, insomnia, fever, confusion. With large doses, irregular
heartbeat, pain and difficulty in urination (*Goodman 1975). Convulsions,
coma, circulatory collapse (Gosselin 1976, p. H-369).
Emergency and First Aid Procedures: (Non-Specific — Drugs, n.o.s.) Move
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Remove and isolate contaminated clothing and
shoes at the site. Keep victim quiet and maintain normal body temperature
(DOT 1984, Guide 11).
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CAS Registry Number: 302-01-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDRAZINE
CAS Registry Number: 302-01-2
Synonyms: Diamine; Hydrazine Anhydrous; Hydrazine Base; Hydrazine, Anhydrous;
Levoxine
Chemical Formula: H4N2
Molecular Weight: 32.05
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.33 mg/Liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 236.3°F, 113.5°C (*Merck 1983)
Specific Gravity (H2O=1): 1.011 at 15°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 14.4 at 25°C (*Sunshine 1969)
Melting Point: 36°F, 2.0°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1983)
Appearance and Odor: Colorless, oily liquid with penetrating ammonia-like
odor (*Merck 1983).
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CAS Registry Number: 302-01-2
Page 2 of 4
HYDRAZINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 ppm (1.3 mg/m3) (NIOSH 1987, p.136)
ACGIH TLV: TWA 0.1 ppm (0.1 mg/ms) (skin) (ACGIH 1986-87, p.20)
IDLH: 80 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Short-term inhalation limits - 1 ppm for 30
minutes (Weiss 1980, p. 509); Occupational Exposure to Hydrazines
Recommended Standard Air Ceiling 0.04 mg/ms/2 hours (*NIOSH/RTECS 1985).
Industrial Substance Suspect of Carcinogenic Potential for Humans --
Recommended TLV 0.1 ppm (skin) (ACGIH 1984, p. 42). NIOSH: 0.04 mg/ms
120-minute ceiling (NIOSH 1987, p.136). SPEGL 0.12 ppm (60 minutes) (NRC
I985b, pp. 5-22).
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 110)
Skin: Yes (NIOSH/OSHA 1978, p. 110)
Ingestion: Yes (NIOSH/OSHA 1978, p. 110)
Health Hazards (Acute, Delayed, and Chronic): Target organs affected
include central nervous system; respiratory system; skin and eyes
(NIOSH/OSHA 1978, p. 110). Chronic exposure in humans may cause pneumonia,
liver and kidney damage. Liver damage may be more severe than kidney
damage (Gosselin 1976, p. 11-247). It is a suspected human carcinogen
(ACGIH 1984, p. 42).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 52°C (*Merck 1983)
Flammable Limits:
LEL: 4.7% (*NFPA 1978)
UEL: 100% (*NFPA 1978)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide
28).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear positive pressure breathing apparatus and protective clothing.
Isolate for one-half mile in all directions if tank car or truck is
involved in fire. Move container from fire area if you can do so without
risk. Dike fire control water for later disposal; do not scatter material.
Spray cooling water on containers that are exposed to flames until well
after fire is out (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: It is a flammable/combustible
material and may be ignited by heat, sparks, or flames. Vapor may travel
to a source of ignition and flash back. Container may explode in heat of
fire. Vapor explosion and poison hazard indoc? : : ors, or in sewers.
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CAS Registry Number: 302-01-2
Page 3 of 4
HYDRAZINE
SECTION IV (continued)
Runoff to sewer may create fire or explosion hazard (DOT 1984, Guide 28).
Vapors form explosive mixtures with air (NFPA 1984, pp. 49-52). May
continue to burn in the absence of air (*Bretherick 1979).
NFPA Flammability Rating: 3
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Can catch fire when in contact with
porous materials such as wood, asbestos, cloth, earth, and rusty metals
(Weiss 1980, p. 509). Incompatible with oxidizers, hydrogen peroxide,
nitric acid, metal oxides, and strong acids (NIOSH/OSHA 1978,
p. 110).
Hazardous Decomposition or Byproducts: Decomposition gives off toxic
nitrogen compound fumes (*Rumack 1975 to Present).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 509)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chemical intermediate for pesticides, blowing agents, photography
chemicals, Pharmaceuticals, antituberculants, textile dyes (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation of vapors (see Section III above). Shut off ignition
sources; no flares, smoking or flames in hazard area. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas. In case of contact with material, immediately flush
skin or eyes with running water for at least 15 minutes (DOT 1984, Guide
28).
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CAS Registry Number: 302-01-2
Page 4 of 4
HYDRAZINE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
CPE POOR/LIMITED*
Chlorobutyl GOOD/LIMITED
Neoprene GOOD/LIMITED
• Nitrile GOOD/LIMITED
PVC GOOD/LIMITED
Teflon POOR/LIMITED
Viton POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 302-01-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDRAZINE
(302-01-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless, fuming, oily liquid.
Odor - Penetrating, ammonialike.
Commercial Form - 97.5% pure liquid in glass bottles, carboys, stainless steel
cans, drums, tank trucks.
Uses - Chemical intermediate, antioxidant, heat stabilizer, corrosion
inhibitor, nickel plating, chain extender in polymerization, component of
rocket fuel, military applications.
Materials to Avoid - Porous materials, oxidizers, acids, water (except for use
in emergency life support).
Caution: Highly flammable and explosive. Avoid sources of extreme heat or
ignition including sparks or fire.
Other Names - Hydrazine anhydrous, Levoxine.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
pyridoxine, phenytoin, phenobarbital.
Signs and Symptoms of Acute Hydrazine Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised.
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EFATG
CAS Registry Number: 302-01-2
Page 2 of 3
HYDRAZINE
Signs and symptoms of acute exposure to hydrazine may include severe eye
irritation, facial numbness, facial swelling, and increased salivation.
Hydrazine vapor may immediately irritate the nose and throat. Headache,
twitching, seizures, convulsions, and coma may also occur. Gastrointestinal
signs and symptoms include anorexia, nausea, and vomiting. Pulmonary edema and
hypotension (low blood pressure) are common. Hydrazine is toxic to the liver,
ruptures red blood cells, and may cause kidney damage. Dermal contact may
result in irritation or severe burns.
Emergency Life-Support Procedures:
Acute exposure to hydrazine may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrazine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with sr and water.
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EFATG
CAS Registry Number: 302-01-2
Page 3 of 3
HYDRAZINE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 309-00-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ALDRIN
CAS Registry Number: 309-00-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 113) 1,4:5,8-
Dimethanonaphthalene, l,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-Hexahydro-;
Aldrex; Aldrite; Aldrosol; Aldrin, Cast Solid; Aldrin Mixture, Dry; Aldrin
Mixture, Liquid; Compound 118; Drinox; ENT 15,949; Hexachlorohexahydro-
endo-exo-Dimethanonaphthalene; 1,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-
Hexahydro-l,4,5,8-Dimethanonaphthalene; l,2,3,4,10,lO-Hexachloro-l,4,4a,5,8,8a-
Hexahydro-exo-l,4-endo-5,8-Dimethanonaphthalene; 1,2,3,4,10,10-Hexachloro-
l,4,4a,5,8,8a-Hexahydro-l,4-endo-exo-5,8-Dimethanonaphthalene; HHDN;
NCI-C00044; Octalene; Seedrin; l,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-
Hexachloro-l,4,4a,5,8,8a-Hexahydro-, (1 alpha, 4 alpha, 4a beta, 5 alpha, 8
alpha, 8a beta)-
Chemical Formula: C12H8C16
Molecular Weight: 364.90
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(cat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 293°F, 145°C at 2 mmHg (Hayes 1982, p. 234); decomposes
(NIOSH/OSHA 1978, p. 42)
Specific Gravity (H2O=1): 1.70 at 20°C (Hayes 1982, p. 234)
Vapor Pressure (mmHg): 0.000006 at 25°C (Hayes 1982, p. 234)
Melting Point: (Pure) 219°F, 104°C; (Technical) 120-140°F, 49-60°C (Hayes
1982, p. 234)
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CAS Registry Number: 309-00-2
Page 2 of 4
ALDRIN
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.027 mg/liter (Hayes 1982, p. 234)
Appearance and Odor: (Pure) Odorless, white solid. (Technical) Tan to
dark brown solid with a mild "chemical" odor (Hayes 1982, p. 234).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 0.25 mg/ms (NIOSH/OSHA 1978, p. 42)
ACGIH TLV: 0.25 mg/ms (skin) (ACGIH 1986-87, p. 9)
IDLH: 100 mg/m3 (NIOSH/OSHA 1978, p. 42)
Other Limits Recommended: NIOSH: Lowest detectable limit (NIOSH 1987,
p. 46)
Routes of Entry: Inhalation: Yes (NIOSH 1978, p. 42)
Skin: Yes (NIOSH 1978, p. 42)
Ingestion: Yes (NIOSH 1978, p. 42)
Health Hazards (Acute, Delayed, and Chronic): Poisoning by aldrin usually
involves convulsions due to its effects on the central nervous system.
Reproductive effects and liver effects have also been reported (Doull 1980,
p. 383; Hayes 1982, p. 235). It is classified as an extremely toxic
chemical. Probable oral lethal dose for humans is between 7 drops and one
oz. for a 150 Ib. adult human (Gosselin 1976, p. 186). Conflicting reports
of carcinogenicity of this compound remain an area of controversy (Doull
1980, p. 383). Similar chemically and lexicologically to dieldrin
(Gosselin 1984, p. 11-285).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Approximately 150°F or higher (no method
given) (NFPA 1984, p. 49-13)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Flammable (Hayes 1982, p. 234). Extinguish by
using water spray, dry chemical, foam, or carbon dioxide. Use water to
keep fire-exposed containers cool. Use water spray to disperse the vapors
(NFPA 1984, p. 49-13).
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CAS Registry Number: 309-00-2
Page 3 of 4
ALDRIN
SECTION IV (continued)
Special Fire Fighting Procedures: Wear full protective clothing (NFPA
1984, p. 49-13) including positive pressure breathing apparatus. Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of chlorine containing compounds (Sax 1984, p. 153).
Commercial solutions may contain flammable or combustible liquids. The dry
powder will not burn (NFPA 1984, p. 49-13). Container may explode in heat
of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: 1 (solution); 0 (dry)
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Avoid concentrated mineral acids,
acid catalysts, acid oxidizing agents, phenols, or active metals (Hayes
1982, p. 234).
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of chlorine containing compounds (Sax 1984, p. 153).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Formerly used as an insecticide; manufacture and use have been discontinued
in the USA (Merck 1983, p. 36). Registered as a termicide in the U.S.
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III). Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with clean
shovel place material into clean, dry container and cover; move containers
from spill area. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
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CAS Registry Number: 309-00-2
Page 4 of 4
ALDRIN
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED**
Butyl/Neoprene POOR/LIMITED**
CPE POOR/LIMITED**
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 309-00-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
ALDRIN
(309-00-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics: ,
Pure Form - Colorless or white crystalline solid.
Odor - None (mild chemical odor in commercial form).
Commercial Forms - Tan to dark brown emulsifiable concentrate, wettable
powders, granules, or dusts in 1- and 5-gaIlon cans or 45-gallon fiber drums.
Use - Insecticide.
Other Names - Aldrite; Aldrosol; Drinox; HHDN; 1,2,3,4,10,10-hexachloro-
l,4,4a,5,8,8a-hexahydro-exo-l,4-endo-5,8-dimethanonaphthalene; Octalene;
Seedrin.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, alcohol, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, D5W, normal saline, Ringer's
lactate, diazepam, phenytoin, phenobarbital, thiopental, succinylcholine.
Signs and Symptoms of Acute Aldrin Exposure:
Signs and symptoms of acute exposure to aldrin may be severe and include
headache, dizziness, agitation, nervousness, tremor, seizures, and coma.
Convulsive episodes may alternate with periods of severe central nervous system
depression. Nausea, vomiting, and diarrhea are common.
Hypertension (high blood pressure), tachycardia (rapid heart rate), and cardiac
arrhythmias (abnormal heart beating) may be noted. Respiratory depression may
lead to respiratory arrest. Contact with the skin, eyes, and mucous membranes
may result in redness and irritation. Victims often have an elevated
temperature.
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EFATG
CAS Registry Number: 309-00-2
i'age 2 of 3
ALDRIN
Emergency Life-Support Procedures:
Acute exposure to aldrin may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to aldrin.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to aldrin.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times. Wash initially with soap and water,
follow with an alcohol wash, then again with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 309-00-2
Page 3 of 3
ALDRIN
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of aldrin is unknown or suspected to be greater than 30 minutes,
do not induce vomiting and proceed to Step 4. Ipecac should not be
administered to children under 6 months of age.
Warning: Ingestion of aldrin may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 315-18-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MEXACARBATE
CAS Registry Number: 315-18-4
Synonyms: Carbamic Acid, Methyl-, 4-Dimethylamino-3,5-xylyl Ester; Zectran;
3,5-Dimethyl-4-(Dimethylamino)Phenyl Methylcarbamate; 3,5-Xylenol,
4-(Dimethylamino)-, Methylcarbamate; 4-(Dimethylamino)-3,5-Xylyl
N-Methylcarbamate; 4-(Dimethylamino)-3,5-Dimethylphenol Methylcarbamate
(Ester); 4-(Dimethylamino)-3,5-Dimethylphenyl N-Methylcarbamate;
4-(Dimethylamino)-3,5-Xylenol, Methylcarbamate (Ester); 4-(N,N-Dimethylamino)-
3,5-Xylyl N-Methylcarbamate; 4-Dimethylamino-3,5-Dimethylphenyl
Methylcarbamate; 4-Dimethylamino-3,5-Dimethylphenyl N-Methylcarbamate;
4-Dimethylamino-3,5-Xylenyl N-Methylcarbamate; 4-Dimethylamino-3,5-Xylyl
Methylcarbamate; 4-Dimethylamino-3,5-Xylyl N-Methylcarbamate; Carbamate,
4-Dimethylamino-3,5-Xylyl, N-Methyl-; Carbamic Acid, Methyl-,
4-(Dimethylamino)-3,5-Dimethylphenyl Ester; Carbamic Acid, Methyl-,
4-(Dimethylamino)-3,5-Xylyl Ester; Dowco 139; Dowco-139; ENT 25,766; ENT 25766;
ENT-25,766; MAZ; Methyl-4- Dimethylamino-3,5-Xylyl Carbamate;
Methyl-4-Dimethylamino-3,5-Xylyl Ester of Carbamic Acid; Methylcarbamic Acid
4-(Dimethylamino)-3,5-Xylyl Ester; Mexicarbate; NCI-C00544; OMS-47; Phenol,
4-(Dimethylamino)-3,5-Dimethyl-, Methylcarbamate (Ester); Zactran; Zectane;
Zextran; Phenol, 4-(Dimethylamino)- 3,5-Dimethyl-, Methylcarbamate (Ester)
Chemical Formula: C12H18N2O2
Molecular Weight: 222.29
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 14 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
-------
CAS Registry Number: 315-18-4
Page 2 of 4
MEXACARBATE
SECTION II (continued)
Vapor Pressure (mmHg): Less than 0.1 at 139°C (*Merck 1983)
Melting Point: 185°F, 85°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.01% at 25°C (*Merck 1983)
Appearance and Odor: White crystalline solid, odorless (*Martin 1974)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s) (DOT 1984, Guide 55)
Skin: Yes (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) (DOT 1984, Guide 55)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic: probable
oral lethal dose for humans is 5-50 mg/kg; between 7 drops and 1
teaspoonful for 70 kg person (150 Ib.) (*Gosselin 1976). (Non-Specific -
Carbamate Pesticide, Solid, n.o.s.) Poisonous; may be fatal if inhaled,
swallowed, or absorbed through skin. Contact may cause burns to skin and
eyes (DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamate Pesticide, Solid,
n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam.
Large fires: water spray, fog, or foam. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Not Found
-------
CAS Registry Number: 315-18-4
Page 3 of 4
MEXACARBATE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Fire may produce irritating or poisonous gases. This
material may burn but does not ignite readily. Container may explode in
heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Martin 1974)
Conditions to Avoid: Subject to photo-decomposition in the solid
state (*IARC 1972-1985).
Incompatibility (Materials to Avoid): Decomposition in highly alkaline
media (*Martin 1974).
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1108).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is an insecticide for non-agricultural uses, e.g., lawn and turf,
flowers, gardens, vines, forest lands, woody shrubs and trees and also a
molluscicide. It is not produced commercially in the United States (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Carbamate Pesticide) Keep sparks, flames, and other
sources of ignition away. Keep material out of water sources and sewer.
Avoid bodily contact with the material (Student 1981, p. 104).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 315-18-4
Page 4 of 4
MEXACARBATE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of carbamate poisoning resemble
those of parathion. This material is similar to carbaryl; symptoms of
carbaryl exposure include nausea, vomiting, abdominal cramps, diarrhea,
excessive salivation, sweating, lassitude and weakness. Runny nose and
sensation of tightness in chest may occur with inhalation exposures.
Blurring or dimness of vision, tearing, eye muscle spasm, loss of muscle
coordination, slurring of speech, and twitching of muscles may also occur
(*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 316-42-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- EMETINE, DIHYDROCHLORIDE
CAS Registry Number: 316-42-7
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 192) Amebicide;
(-)-Emetine Dihydrochloride; 1-Emetine Dihydrochloride; Emetine, Hydrochloride;
NSC-33669
Chemical Formula: C29H40N2O4 2HC1
Molecular Weight: 553.63
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(rat) 0.012 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 455-491°F, 235-255°C decomposes (Merck 1983, p. 514)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Contains water of hydration varying from 3 to 8
molecules of water; 1 g of hydrated salt dissolves in 7 mL (Merck 1983,
P. 514)
-------
CAS Registry Number: 316-42-7
Page 2 of 4
EMETINE, DIHYDROCHLORIDE
SECTION II (continued)
Appearance and Odor: Clusters of needles after drying at 221°F, 105°C;
turns yellow on exposure to light or heat ((Merck 1983, p. 514)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1275)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally. It is an eye irritant (Sax 1984, p. 1275). (Non-Specific —
Emetine) Emetine is classified as extremely toxic. Probable oral lethal
dose for humans is 5-50 mg/kg, or between 7 drops and one teaspoon for a
150-lb person (Gosselin 1984, p. II-244).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Emetine is an alkaloid (Merck 1983, p. 513).
Extinguishing methods for alkaloid salts are as follows. Small fires: dry
chemical, carbon dioxide, water spray, or foam. Large fires: water spray,
fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Procedures for alkaloid salts include
the following. Move container from fire area if you can do so without
risk. Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Wear positive pressure
breathing apparatus and special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of chlorides, hydrogen chloride and oxides of
nitrogen (Sax 1984, p. 1275).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 316-42-7
Page 3 of 4
EMETINE, DIHYDROCHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Turns yellow on exposure to light or heat (Merck
1983, p. 514)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of chlorides, hydrogen chloride, and oxides of
nitrogen (Sax 1984, p. 1275).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Emetine, dihydrochloride is an injectable form of emetine (Oilman 1984, p.
1051). It is an antiamebic (Merck 1983, p. 514). Emetine is the active
ingredient of Ipecac (Gosselin 1984, p. 11-244).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
The following procedures should be used for alkaloid salts. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do it without risk. Use water spray to
reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 316-42-7
Page 4 of 4
EMETINE, DIHYDROCHLORIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Emetine) Symptoms
include nausea, vomiting, diarrhea, muscle weakness, pain, tenderness,
hypotension, precordial pain and rapid heartbeat (Gosselin 1984, p.
11-244).
Emergency and First Aid Procedures: Emetine is an alkaloid (Merck 1983,
p. 513). Procedures for alkaloid salts are as follows. Move victim to
fresh air; call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
be delayed; keep victim under observation (DOT 1984, Guide 55).
COMMENTS:
Sources searched but no information found:
NFPA 1984
Weiss 1980
ACGIH 1983
NIOSH/OSHA 1978
Encyc Occupat Health and Safety 1983
Weast 1979
Physicians' Desk Reference 1985
Farm Chemicals Handbook 1984
-------
CAS Registry Number: 327-98-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRICHLORONATE
CAS Registry Number: 327-98-0
Synonyms: 5082A; Agrisil; Agritox; Bay 37289; Bayer 37289; Bayer 5081; Bayer
S 4400; Chemagro 37289; ENT 25,712; ENT-25712; Ethyl
Trichlorophenylethylphosphonothioate; Fenophosphon; Fitosol; O-Ethyl
O-2,4,5-Trichlorophenyl Ethylphosphonothioate; Phenol, 2,4,5-Trichloro-,
O-Ester with O-Ethyl Ethylphosphonothioate; Phosphonothioic Acid, Ethyl-,
O-Ethyl O-(2,4,5-Trichlorophenyl) Ester; Phytosol; Richloronate; S 4400;
Trichloronat
Chemical Formula: C10H12C18O2PS
Molecular Weight: 333.60
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(cat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 226°F, 108°C at 0.01 mmHg (*Worthing 1979)
Specific Gravity (H2O=1): 1.365 at 20°C/4°C (*Worthing 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 50.mg/liter at 20°C (*Worthing 1979)
-------
AS Registry Number: 327-98-0
i'age 2 of 4
TRICHLOi ONATE
SECTION II (continued)
Appearance and Odor: Amber colored liquid (*Worthing 1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific -- Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Ingestion: Yes (Sax 1984, p. 1397)
Health Hazards (Acute, Delayed, and Chronic): Material is an
organophosphate (*Rumack 1975 to Present) and toxic effects are due to
action on the nervous system (Hayes 1982, p. 301). It has high oral
toxicity (Sax 1984, p. 1397) and death can occur in acute poisonings
(*DeReuch 1979). Delayed neurotoxicity has been reported (*Rumack 1975 to
Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphate Pesticide,
Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphate
Pesticide, Liquid, n.o.s.) Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material. Wear positive pressure
breathing apparatus and special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of chlorine containing compounds, phosphorus oxides,
and sulfur oxides (Sax 1984, p. 1397).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 327-98-0
Page 3 of 4
TRICHLORONATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of chlorine containing compounds, phosphorus oxides,
and sulfur oxides (Sax 1984, p. 1397).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Non-systemic insecticide (*Worthing 1979). Not marketed in the U.S.A. or
Canada (Farm Chemicals Handbook 1984, p. C-7). Not registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). (Non-Specific — Organophosphate
Pesticide, Liquid, n.o.s.) Do not touch spilled material; stop leak if you
can do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal. Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 327-98-0
Page 4 of 4
TRICHLORONATE
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Headache, dizziness, nausea, salivation,
vomiting, abdominal pain, diarrhea, chest pain, decreased heart rate,
excessive discharge of mucous from the air passages, difficult breathing,
contraction of the pupil, blurred vision, profuse perspiration, muscle
twitching and spasms, profound weakness, psychotic behavior,
uncoordination, unconsciousness, rarely convulsions. Low level absorption
syndrome is similar to influenza. High dosage may cause toxic psychosis
similar to alcoholism. Exposures may be misdiagnosed as asthma and heart
failure (*Rumack 1975 to Present).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphate
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 353-42-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BORON TRIFLUORIDE COMPOUND WITH METHYL ETHER
(1:1)
CAS Registry Number: 353-42-4
Synonyms: (NIOSH/RTECS 1983 Synonym, Volume 1, p. 741) Boron,
Trifluoro(Oxybis(methane))-,(T-4)-; Boron Trifluoride-Dimethyl Ether; (SANSS
1983 Synonyms): Methyl Ether, compound with Boron Fluoride (1:1); Boron
Fluoride Complex with Dimethyl Ether; Boron Trifluoride Compound with Methyl
Ether; Boron Trifluoride Dimethyl Ether Addition Compound; Boron Trifluoride
Dimethyl Etherate; Boron Trifluoride Dimethyl Ether Complex
Chemical Formula: C2H6O BFS
Molecular Weight: 113.89
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCjow inhalation
(guinea pig) 0.233 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 126°C at 760 mmHg (Aldrich 1986, p. 190)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 353-42-4
Page 2 of 4
BORON TRIFLUORIDE COMPOUND WITH METHYL ETHER (1:1)
SECTION II (continued)
Appearance and Odor: Not Found
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 515)
Skin: Yes (DOT 1984, Guide 29)
Ingestion: Yes (Non-Specific — Boron Compounds)
(Sax 1984, p. 513)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by inhalation (Sax 1984, p. 515).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material may react violently with water. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 29).
Special Fire Fighting Procedures: Wear self-contained, positive- pressure
breathing apparatus and full protective clothing. Move containers from
fire area if possible. Do not get water inside containers. Spray cooling
water on containers that are exposed to flame until well after fire is out.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire. Isolate for 1/2 mile in all
directions if tank car or truck is involved in fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases. Flammable/combustible material which may be ignited by
heat spark or flame. Vapors may travel to a source of ignition and flash
back. Container may explode in heat of fire. Vapor explosion hazard
indoors, outdoors, or in sewer. Runoff to sewer may create fire or
explosion hazard (DOT 1984, Guide 29).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 353-42-4
Page 3 of 4
BORON TRIFLUORIDE COMPOUND WITH METHYL ETHER (1:1)
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of fluorides (Sax 1984, p. 515).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away and isolate hazard area. Stay upwind and
keep out of low areas. Shut off ignition sources. Do not touch
spilled material. Use water spray to reduce vapors, but do not get
water inside containers. For small spills, absorb with sand or other
noncombustible absorbent material and place into containers. For large
spills, dike far ahead of spill for later disposal (DOT 1984, Guide 29).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Contact may cause burns to skin and eyes
(DOT 1984, Guide 29).
Emergency and First Aid Procedures: Move victim to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. Remove and isolate contaminated clothing at site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 29).
-------
CAS Registry Number: 353-42-4
Page 4 of 4
BORON TRIFLUORIDE COMPOUND WITH METHYL ETHER (1:1)
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 359-06-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FLUOROACETYL CHLORIDE
CAS Registry Number: 359-06-8
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 252): Acetyl Chloride,
Fluoro-; TL 670
Chemical Formula: C2H2C1FO
Molecular Weight: 96.49
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(guinea pig) 0.1 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 359-06-8
Page 2 of 4
FLUOROACETYL CHLORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1430)
Skin: Not Found
Ingestion: Yes (Non-Specific -- Chloroacetyl
Chloride) (NFPA 1984, p. 49-29)
Health* Hazards (Acute, Delayed, and Chronic): Highly toxic by inhalation
(Sax 1984, p. 1430). (Non-Specific - Chloroacetyl Chloride) Corrosive to
skin and irritating to eyes (NFPA 1984, p. 49-29).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Chloroacetyl Chloride and
Fluoroacetic Acid) Extinguish with dry chemical, carbon dioxide, water
spray, fog, or foam (DOT 1984, Guide 59).
Special Fire Fighting Procedures: (Non-Specific - Chloroacetyl Chloride
and Fluoroacetic Acid) Spray cooling water on containers that are exposed
to flames until well after fire is out. Move container from fire area if
you can do so without risk. Do not get water in container, as material may
react violently with water (DOT 1984, Guide 59).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of chlorine and fluorine-containing compounds (Sax
1984, p. 1430). (Non-Specific -- Chloroacetyl Chloride and Fluoroacetic
Acid) Some of these materials may ignite combustibles (i.e., wood, paper,
oil, etc.) or react violently with water (DOT 1984, Guide 59).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 359-06-8
Page 3 of 4
FLUOROACETYL CHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of chlorine and fluorine-containing compounds (Sax
1984, p. 1430).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Do not touch spilled material; stop leak if
you can do so without risk. Use water spray to reduce vapors
(may react violently with water). Small spills: absorb with
sand or other non-combustible absorbent material and place into containers
for later disposal. Large spills: dike far ahead of spill for later
disposal (DOT 1984, Guide 59).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific ~ Chloroacetyl
Chloride and Fluoroacetic Acid) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Remove and
isolate contaminated clothing and shoes at site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 59).
-------
CAS Registry Number: 359-06-8
Page 4 of 4
FLUOROACETYL CHLORIDE
COMMENTS
Sources searched but no information found:
Weast 1979
Hawley 1981
Hayes 1982
DASE 1980
ACGIH 1983
NIOSH/OSHA 1978
Merck 1983
Oilman 1985
Gosselin 1984
Weiss 1980
Clayton and Clayton 1981-82
Farm Chemicals Handbook 1984
Doull 1980
Buchel 1983
-------
CAS Registry Number: 371-62-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHYLENE FLUOROHYDRIN
CAS Registry Number: 371-62-0
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 252): Ethanol, 2-Fluoro-;
beta-Fluoroethanol; 2-Fluoroethanol; TL 741
Chemical Formula: C2H5FO
Molecular Weight: 64.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(dog) 0.007 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 218.3°F, 103.5°C (Weast 1979, p. C-297)
Specific Gravity (H2O=1): 1.1040 at 20°C/4°C (Weast 1979, p. C-297)
Vapor Pressure (mmHg): Not Found
Melting Point: -15.61°F, -26.45°C (Weast 1979, p. C-297)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (Weast 1979, p. C-297)
Appearance and Odor: Liquid (Hayes 1983, p. 500)
-------
AS Registry Number: 371-62-0
. age 2 of 4
ETHYLL. _ FLUOROHYDRIN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1437)
Skin: Yes (Sax 1984, p. 1437)
Ingestion: Yes (Hayes 1982, p. 500)
Health Hazards (Acute, Delayed, and Chronic): Toxicity rating is the same
as for fluoroacetate, super toxic. The probable oral lethal dose in humans
is a taste (less than 7 drops) for a 70 kg (150 Ib.) person (Gosselin 1984,
p. 11-198). The chemical is highly toxic when inhaled or absorbed through
the skin (Sax 1984, p. 1437). Toxicity depends on its oxidation to
fluoroacetate by tissue alcohol dehydrogenase (Hayes 1982, p. 500).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 31°C (Hayes 1982, p. 500)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Toxic fluoride fumes may be emitted
in a fire (Sax 1984, p. 1437).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluorides (Sax 1984, p. 1437).
-------
CAS Registry Number: 371-62-0
Page 3 of 4
ETHYLENE FLUOROHYDRIN
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Ethylene Fluorohydrin is used as a rodenticide (Hayes 1982, p. 500),
insectide (Gosselin 1984, p. III-193), and acaricide (Buchel 1983, p. 177).
Not registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII « PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
(Non-Specific -- Fluoroacetic Acid) Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce
vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 59).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
CPE GOOD/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include tremors, severe muscular
weakness, nausea, headache, and slight swelling of the liver (Hayes 1982,
p. 500). Delayed convulsant (Gosselin 1984, p. II-198).
-------
CAS Registry Number: 371-62-0
Page 4 of 4
ETHYLENE FLUOROHYDRIN
SECTION IX (continued)
Emergency and First Aid Procedures: Acute poisoning should be treated
like poisoning by fluoroacetate. Ethylene fluorbhydrin (2-fluoroethanol)
is listed among the organic fluorine derivatives of fluoroacetic acid
(Hayes 1982, p. 501). The emergency procedures for f luoroacetic acid are:
move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Remove and isolate contaminated clothing
and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 59).
COMMENTS
Sources searched but no information found:
Student 1981
DASE 1980
Hawley 1981
NFPA 1984
Weiss 1980
Merck 1983
CHRIS 1978
Farm Chemicals Handbook 1984
-------
CAS Registry Number: 379-79-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ERGOTAMINE TARTRATE
CAS Registry Number: 379-79-3
Synonyms: (SANSS 1983 Synonyms) Ergotamine Bitartrate; Gotamine Tartrate;
Gynergen; Neo-ergotin; Ergotaman-3',6',18-Trione,
12'-Hydroxy-2'-Methyl-5'-(Phenylmethyl)-, (S'.alpha.)-, [R-(R*,R*)]-
2,3-Dihydroxybutanedioate (2:1) (Salt); Ergam; Ergate; Ergomar; Etin; Exmigra;
Rigetamin; Secagyn; Secupan; Ergotamine, Tartrate (2:l)(Salt); Component of
Cafergot
Chemical Formula: C66H70N10O10-C4H6O6
Molecular Weight: 1313.56
SECTION I --REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat,rabbit) 1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 397°F, 203°C, decomposes (Merck 1983, p. 529)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g/500 mL (Merck 1983, p. 529)
-------
CAS Registry Number: 379-79-3
Page 2 of 3
ERGOTAMINE TARTRATE
SECTION II (continued)
Appearance and Odor: Powder or liquid forms available as drugs (Gilman
1985, p. 938).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Gilman 1985, p. 938)
Skin: Not Found
Ingestion: Yes (NIOSH/RTECS 1983, p. 209)
Health Hazards (Acute, Delayed, and Chronic): High oral toxicity and a
convulsant in humans (Sax 1984, p. 1295).
Medical Conditions Generally Aggravated by Exposure: People with liver
damage are at a greater risk (Gilman 1985, p. 937).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Protect from light and heat (Merck
1983, p. 529)
Hazardous Decomposition or Byproducts: When * :' to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 198-,. .).
-------
CAS Registry Number: 379-79-3
Page 3 of 3
ERGOTAMINE TARTRATE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
The major uses of the ergot alkaloids fall into two categories:
applications in obstetrics and treatment of migraine headaches (Oilman
1985, p. 937).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Alkaloid, n.o.s.) Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do so without risk.
Use water vapor to reduce vapors. Absorb spills with sand or other
noncombustible absorbent material. Small dry spills: with clean shovel
place material into clean, dry container and cover; move containers from
spill area. For large spills, dike far ahead of spill for later
disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea and vomiting occur in some
patients after oral administration. Weakness in the legs is common and
muscle pains in the extremities may occur. Numbness and tingling of the
fingers and toes may also occur (Oilman 1985, p. 938).
Emergency and First Aid Procedures: (Non-Specific -- Alkaloid, n.o.s.)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed; keep victim under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 465-73-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ISODRIN
CAS Registry Number: 465-73-6
Synonyms: l,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-Hexachloro-
l,4,4a,5,8,8a-Hexahydro-, endo,endo-; Compound 711; ENT 19,244; Experimental
Insecticide 711; l,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-Hexahydro-l,4; 5,8-
endo,endo-Dimethanonaphthalene; 1,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-
Hexahydro-endo,endo-l,4:5,8-Dimethanonaphthalene; l,4:5,8-Dimethanonaphthalene,
l,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-Hexahydro-, (1 alpha, 4 alpha, 4a beta,
5 beta, 8 beta, 8a beta)-; SD 3418
Chemical Formula: C12H8C16
Molecular Weight: 364.90
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 464-468°F, 240-242°C (Sax 1984, p. 1641)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 465-73-6
Page 2 of 4
ISODRIN
SECTION II (continued)
Appearance and Odor: Solid (*Hawley 1977)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Aldrin)
(Sax 1984, p. 153)
Skin: Yes (Sax 1984, p. 1641)
Ingestion: Yes (Sax 1984, p. 1641)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely toxic. Probable oral lethal dose for humans is 5-50 mg/kg or
between 7 drops and 1 teaspoonful for a 70 kg (150 Ib.) person. It causes
renal damage and hyperactivity of sympathetic nervous system (*Gosselin
1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Material is related to aldrin (*Gosselin 1976).
(Non-Specific — Aldrin) Extinguish by using water spray, dry chemical,
foam, or carbon dioxide. Use water to keep fire exposed containers cool
(NFPA 1984, p. 49-13).
Special Fire Fighting Procedures: (Non-Specific - Aldrin) Wear full
protective clothing (NFPA 1984, p. 49-13) including positive pressure
breathing apparatus. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Aldrin) This
material may burn but may not ignite readily. Container may explode in
heat of fire. Fire and runoff from fire control water may produce
irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 465-73-6
Page 3 of 4
ISODRIN
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*White-Stevens 1971)
Stable:
Conditions to Avoid: Reactions induced by light or acid
(*White-Stevens 1971)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Material is related to aldrin
(*Gosselin 1976). (Non-Specific — Aldrin) When heated to decomposition
it emits toxic fumes of chlorine (Sax 1984, p. 153).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
No longer used as a pesticide (*NIOSH/RTECS 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Material is related to aldrin (*Gosselin 1976). (Non-Specific -- Aldrin)
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Remove and isolate contaminated clothing at the site.
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry containers and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms experienced are similar to
poisoning by dieldrin and aldrin, including overall discomfort, headache,
nausea, vomiting, dizziness, tremors, convulsions, rise in blood pressure,
fever, disturbances in sleep and behavior, and rapid heartbeat. Death from
respiratory arrest may occur in coma (*Gosselin 1976, *Merck 1976).
-------
CAS Registry Number: 465-73-6
Page 4 of 4
ISODRIN
SECTION IX (continued)
Emergency and First Aid Procedures: Procedures are similar to those for
dieldrin and aldrin poisoning (*Gosselin 1976). Move victim to fresh air;
call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
be delayed; keep victim under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 470-90-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHLORFENVINFOS
CAS Registry Number: 470-90-6
Synonyms: Supona; 2,4-Dichloro-alpha-(Chloromethylene)Benzyl Diethyl
Phosphate; 2-Chloro-l-(2,4-Dichlorophenyl)Ethenyl Diethyl Ester Phosphoric
Acid; 2-Chloro-l-(2,4-Dichlorophenyl)Vinyl Diethyl Phosphate; 4072; Benzyl
Alcohol, 2,4-Dichloro-alpha-(Chloromethylene)-, Diethyl Phosphate;
beta-2-Chloro-l-(2',4'-Dichlorophenyl)Vinyl Diethyl Phosphate; Birlan; Birlane;
C8949; Chlofenvinphos; Chlorofenvinphos; Chlorphenvinfos; Chlorphenvinphos;
Compund 4072; CVP; CVP (Pesticide); Dermaton; Diethyl
l-(2,4-Dichlorophenyl)-2-Chlorovinyl Phosphate; Diethyl 2-Chloro-l-
(2,4-Dichlorophenyl)Vinyl Phosphate; ENT 24969; GC 4072; GS 4072; QMS 1328;
Phosphoric Acid, 2-Chloro-l-(2,4-Dichlorophenyl)Ethenyl Diethyl Ester;
Phosphoric Acid, 2-Chloro-l-(2,4-Dichlorophenyl)Vinyl Diethyl Ester; Sapecron;
SD 4072; Shell 4072; Supone; Vinyphate
Chemical Formula: C12H14C13O4P
Molecular Weight: 359.56
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 333-338°F, 167-170°C at 0.5 mmHg (*Worthing 1979)
Specific Gravity (H2O=1): 1.36 at 15.5°C/16.5°C (*Worthing 1979)
Vapor Pressure (mmHg): 0.000004 at 20°C (*Worthing 1979)
Melting Point: -2 to -9°F; -19 to -23°C (*Worthing 1979)
-------
CAS Registry Number: 470-90-6
Page 2 of 4
CHLOkf LNVINFOS
SECTION I (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 145 mg/liter at 23°C (*Worthing 1979).
Appearance and Odor: Amber-colored liquid with mild chemical odor
(*Worthing 1979; *Spencer 1973).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) (DOT 1984,
Guide 55)
Skin: Yes (Hayes 1982, p. 396)
Ingestion: Yes (Hayes 1982, pp. 396-97)
Health Hazards (Acute, Delayed, and Chronic): Acute: cholinesterase
inhibitor which affects central nervous system. Severe illness or death
possible (Hayes 1982, pp. 396-397). Convulsions or coma and death
(*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material. Wear positive pressure
breathing apparatus and special protective clothirr- ^DOT 1984, Guide 55).
-------
CAS Registry Number: 470-90-6
Page 3 of 4
CHLORFENVINFOS
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) This material may burn but does not ignite
readily. Container may explode in heat of fire. Fire and runoff from fire
control water may produce irritating or poisonous gases (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes, when stored in glass or polyethylene lined
containers (*Worthing 1979)
Conditions to Avoid: Alkaline aqueous solutions (*Merck 1976)
Incompatibility (Materials to Avoid): Iron, steel, and brass (*Worthing
1979).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used for control of ticks, flies, lice, and mites on cattle and for
blowfly, lice, ked, and itchmite on sheep (*Farm Chemicals Handbook 1980).
Controls fleas and mites on dog; do not use on cats. Used on organic
wastes and breeding places of fly larvae, including diary barns (*Rossoff
1974; Hayes 1982, p. 396). Also used as a foliage insecticide for
potatoes, rice, maize, and sugar cane. Used to control soil insects, i.e.,
rootflies, rootworms, and cutworms (*Spencer 1973).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, Liquid, n.o.s.) In case of
spill or leak, do not touch spilled material; stop leak if you can do it
without risk. Use water spray to reduce vapors. Small spills: take up
with sand or other non-combustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal. Keep unnecesary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
-------
CAS Registry Number: 470-90-6
Page 4 of 4
CHLORFENVINFOS
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms typical of cholinesterase
poisoning. Nausea is often first symptom, with vomiting, abdominal cramps,
diarrhea, and excessive salivation. Headache, giddiness, weakness,
tightness in chest, blurring of vision, pinpoint pupils, loss of muscle
coordination, and difficulty breathing. Convulsions and coma precede death
(*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 502-39-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYLMERCURIC DICYANAMIDE
CAS Registry Number: 502-39-6
Synonyms: (Cyanoguanidino)Methylmercury; Agrosol; Cyano(Methylmercuri)
Guanidine; Guanidine, Cyano(Methylmercurio)-; Guanidine, Cyano-, Methylmercury
Deriv; Mercury, (3-Cyanoguanidino)Methyl-; Mercury, (Cyanoguanidinato)Methyl-;
Mercury, (Cyanoguanidinato-N')Methyl-; Methyl Mercuric Dicyandiamide;
Methylmercuric Cyanoguanidine; MMD; Morsodren; Morton EP-227; Morton Soil
Drench; Morton Soil-Drench-C; N-Cyano-N'-(Methyl-mercury)Guanidine;
Pano-Drench; Pano-Drench 4; Panodrin A-13; Panogen; Panogen 15;
Panogen 43; Panogen 8; Panogen PX; Panogen Turf Spray; Panogen (Old);
Panospray 30; R 8; R 8 (Fungicide); MEMA; Methylmercuric Dicyandiamide;
Methylmercury dicyandiamide; Panogen Turf Fungicide
Chemical Formula: CsH6HgN4
Molecular Weight: 298.72
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.000065 at 35°C (*Martin and Worthing 1974)
Melting Point: 313°F, 156°C (*Hawley 1981)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 502-39-6
Page 2 of 4
METHYLMERCURIC DICYANAMIDE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 2.17 g/100 ml at room temperature (*Martin and
Worthing 1974); soluble (Hawley 1981, p. 295)
Appearance and Odor: Crystals (*Hawley 1981)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.01 mg/m3; ceiling concentration 0.04 mg/m3
(NIOSH/RTECS 1983, Volume 2, p. 662)
ACGIH TLV: TWA 0.01 mg (Hg)/m3; STEL (ceiling) 0.03 mg (Hg)/m3 (skin)
(NIOSH/RTECS 1983, Volume 2, p. 662)
IDLH: Not Found
<
Other Limits Recommended: IDLH for organo (alkyl) mercury compounds is 10
mg/m3 (NIOSH/OSHA 1978, p. 144).
Routes of Entry: Inhalation: Yes (Gosselin 1984, p. 11-137)
Skin: Yes (Gosselin 1984, p. II-137)
Ingestion: Yes (Sax 1984, p. 1868)
Health Hazards (Acute, Delayed, and Chronic): Methylmercuric dicyanamide
is extremely toxic to humans. The probable lethal dose for humans is 5-50
mg/kg of body weight (between 7 drops and one teaspoon for a 150 Ib.
person) (*Gosselin 1984). Humans may be poisoned by feeding on the flesh
of animals which have ingested this fungicide (*Clark 1981). Eating
treated seeds may also cause poisoning. The poisoning may show delayed
manifestations on the nervous system. Patients frequently become gradually
worse after their illness is recognized and exposure is stopped (Hayes,
1982, p. 21). This compound is a strong skin irritant and produces
blisters and other dermatitis (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Mercury-Based Pesticide, n.o.s.)
This material may burn but will not ignite readily. For small fires, use
dry chemical, carbon dioxide, water spray, or foam. For large fires, use
water spray, fog, or foam (DOT 1984, Guide 55).
-------
CAS Registry Number: 502-39-6
Page 3 of 4
METHYLMERCURIC DICYANAMIDE
SECTION IV (continued)
Special Fire Fighting Procedures: (Non-Specific -- Mercury-Based
Pesticide, n.o.s.) Fight fire from maximum distance. Dike fire control
water for later disposal. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Mercury-Based
Pesticide, n.o.s.) This material may burn but does not ignite readily.
Container may explode in heat of fire. Fire and runoff from fire control
water may produce irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Martin and Worthing 1974)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of mercury and nitrogen oxides (Sax 1984, p. 1868).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Fungicide; a seed, soil, and turf treatment (Buchel 1983, p. 249)
especially for cereals, sorghum, sugar beets, cotton, and flax (Hayes 1982,
p. 20). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Mercury-Based Pesticide n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering. Remove and isolate
contaminated clothing at the site. Do not touch spilled material. Use
water to reduce vapors. In event of spill or leak: take up with absorbent
material and place in containers with covers. Small dry spill:
with clean shovel place material into clean, dry container and cover;
move containers from spill area. Dike far ahead of spill if large
(DOT 1984, Guide 55).
-------
CAS Registry Number: 502-39-6
Page 4 of 4
METHYLMERCURIC DICYANAMIDE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Prolonged exposure to skin may produce
. blisters (*Gosselin 1984). In the case of ingestion there is nausea and
abdominal pain. Vomiting and diarrhea may occur. Burning or prickling of
the lips, tongue, and extremities. The patient may be confused,
hallucinate, be irritable, have disturbed sleep, lose muscular coordination
and lose memory. Visual fields may narrow concentrically; emotional
instability may occur as well as inability to concentrate, with stupor and
coma (*Rumack 1975 to Present).
Emergency and First Aid Procedures: (Non-Specific -- Mercury-Based
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 504-24-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PYRIDINE, 4-AMINO-
CAS Registry Number: 504-24-5
Synonyms: 4-Aminopyridine; 4-AP; 4-Pyridinamine; 4-Pyridylamine; Amino-4
Pyridine; Avitrol; gamma-Aminopyridine; MI-W-3; p-Aminopyridine; Phillips 1861;
VMI 10-3
Chemical Formula: CEH6N2
Molecular Weight: 94.13
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 524.3°F, 273.5°C (*Hawley 1977)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 318.0°F, 158.9°C (*Hawley 1977)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Moderately soluble (*Farm Chemicals Handbook 1981)
Appearance and Odor: White crystalline material with no odor (*Farm
Chemicals Handbook 1981).
-------
CAS Registry Number: 504-24-5
Page 2 of 4
PYRIDINE, 4-AMINO-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Material may be fatal if
inhaled, swallowed or absorbed through skin. Contact may cause burns to
skin and eyes (*DOT 1984). Material affects neural transmission. In
sufficient concentrations, material may cause metabolic acidosis,
respiratory arrest, and cardiac arrhythmias (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: The material may burn but will not ignite easily.
To extinguish use dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear positive pressure self-contained
breathing apparatus and special protective clothing. Move container from
fire area if you can do so without risk. Fight fire from maximum distance
possible. Control runoff water with dikes and prevent material from
scattering (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Material may produce irritating or
poisonous gases in fire. Runoff from fire control water may give off
poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Farm Chemicals Handbook 1981)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 504-24-5
Page 3 of 4
PYRIDINE, 4-AMINO-
SECTION V (continued)
Hazardous Decomposition or Byproducts: It may emit irritating or
poisonous gases in fire conditions (DOT 1984, Guide 55).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
SECTION VI -- USE INFORMATION
Material is used as an avicide (bird repellant), an intermediate and as a
fixer in some textile dyes (*Rumack 1975 to Present, *Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate the hazardous area and deny entry.
Stay upwind. Do not touch spilled material; stop leak if possible
without risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (*DOT
1984).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Nitrile POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Rapid onset of disagreeable taste,
immediate burning of throat, and abdominal discomfort; in addition,
weakness, dizziness, disorientation, and seizures may occur. Delayed
symptoms of oral ingestion include elevated liver enzymes, and respiratory
arrest (*Rumack 1975 to Present).
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CAS Registry Number: 504-24-5
Page 4 of 4
PYRIDINE, 4-AMINO-
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running water
for at least fifteen minutes (*DOT 1984).
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CAS Registry Number: 505-60-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MUSTARD GAS
CAS Registry Number: 505-60-2
Synonyms: Sulfide, bis(2-Chloroethyl); l,l'-Thiobis(2-Chloroethane);
1 -Chloro-2-(beta-Chloroethylthio)Ethane; 2,2'-Dichlorodiethyl Sulfide;
2,2'-Dichlorodiethyl Sulphide; 2,2'-Dichloroethyl Sulfide; 2,2'-Dichloroethyl
Sulphide; beta, beta'-Dichloroethyl Sulfide; beta, beta'-Dichloroethyl
Sulphide; beta,beta-Dichlor-Ethyl-Sulphide; Bis(2-Chloroethyl) Sulfide;
Bis(2-Chloroethyl) Sulphide; Bis(beta-Chloroethyl) Sulfide;
Bis(beta-Chloroethyl) Sulphide; Di-2-Chloroethyl Sulfide; Di-2-Chloroethyl
Sulphide; Distilled Mustard; Ethane, l,l'-Thiobis(2-Chloro-; H; HD; Kampfstoff
"Lost"; Mustard HD; Mustard Vapor; Mustard, Sulfur; S Mustard; S-Lost;
S-Yperite; Schwefel-Lost; Sulfur Mustard; Sulfur Mustard Gas; Sulphur Mustard;
Sulphur Mustard Gas; Yellow Cross Liquid; Yperite
Chemical Formula: C4H8C12S
Molecular Weight: 159.08
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.42 mg/liter/2 minutes (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 419-423°F, 215-217°C (*Merck 1976)
Specific Gravity (H2O=1): 1.274 at 20°C/4°C (liquid) (*Merck 1976)
Vapor Pressure (mmHg): 0.090 at 30°C (*Merck 1976)
Melting Point: 55-57°F, 13-14°C (*Merck 1976)
Vapor Density (AIR=l):-~5.4 (*Sax 1975)
-------
CAS Registry Number: 505-60-2
Page 2 of 4
MUSTARD GAS
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.68 g/liter at 25°C (*IARC 1972-1985); very
sparingly soluble in water (Merck 1983, p. 904).
Appearance and Odor: Colorless oily liquid (*IARC 1972-1985) with a weak,
sweet odor (*Merck 1976) or garlic-like odor (U.S. Army 1975, p. 3-8).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): The median lethal dosage is
1500 mg-minute/m3 for inhalation and 10,000 mg-minute/ms for skin
absorption (masked personnel). The median incapacitating dosage is 200
mg-minute/m3 for eye injury and 2000 mg-minute/ms for skin absorption
(masked personnel). Wet skin absorbs more material than dry skin (U.S.
Army 1975, p. 3-8). May cause death or permanent injury after very short
exposure to small quantities (*Sax 1975). It is a blistering gas and is
highly irritating to eyes, skin, and lungs. Pulmonary lesions are often
fatal (Sax 1984, pp. 461-462). Permanent eye damage and severe respiratory
impairment. It is a carcinogen (Merck 1983, p. 904).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 221°F, 105°C (*Sax 1975)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with water, foam, dry chemical, or
carbon dioxide (*Sax 1975).
Special Fire Fighting Procedures: Protective clothing and self-contained
breathing apparatus required in presence of mustard g?' '*Sax 1975). Cool
all affected containers with flooding quantities of ^ .-..pply water
from as far a distance as possible (Student 1981, p
-------
CAS Registry Number: 505-60-2
Page 3 of 4
MUSTARD GAS
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Can be ignited by large explosive
charge. When heated to decomposition, emits highly toxic fumes of oxides
of sulfur and chlorine containing compounds. Reacts with water or steam to
produce toxic and corrosive fumes (*Sax 1975). Containers may rupture
violently in a fire (Student 1981, p. 358).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes; hydrolyzed in aqueous solution (*IARC
1972-1985)
Stable:
Conditions to Avoid: High heat; contact with acid or acid fumes (*Sax
1984, p. 482).
Incompatibility (Materials to Avoid): Incompatible with bleaching powder
(Sax 1984, p. 482). Reacts violently with oxidizing materials. Reacts
with water or steam to produce toxic and corrosive fumes (*Sax 1975).
Hazardous Decomposition or Byproducts: Emits highly toxic fumes of oxides
of sulfur and chlorine containing compounds when heated to decomposition or
on contact with acid or acid fumes (*Sax 1974)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It has been used as a chemical warfare agent (*IARC 1972-1985) and as a
chemical intermediate. It is not produced commercially in the U.S. (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
To clean up a spill, cover with up to 15 percent calcium hypochloride.
Place in container; neutralize after 12 hours if necessary (*Rumack 1975 to
Present). Keep sparks, flames, and other sources of ignition away. Keep
material out of water sources and sewers. Attempt to stop leak if without
hazard. Use water spray to knock down vapors. Avoid breathing vapors and
bodily contact with the material. Keep upwind. Wash away any material
which may have contacted the body with copious amounts of soap and water.
Downwind evacuation must be considered (Student 1981, p. 358).
-------
CAS Registry Number: 505-60-2
Page 4 of 4
MUSTARD GAS
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: May cause conjunctivitis and blindness.
In 1-12 hours there may be coughing, swollen eyelids, reddened skin, and
severe itching. There may be swelling and destruction of tissue in the
respiratory tract and exposed skin. Ingestion may cause nausea and
vomiting (*Merck 1976).
Emergency and First Aid Procedures: Remove patient from contaminated
atmosphere as rapidly as possible. Irrigate exposed eyes with water for at
least 15 minutes. Wash exposed areas of the skin twice with soap and
water. Local lesions should be cleaned and treated similarly to burns with
emollients (*Rumack 1975 to Present).
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CAS Registry Number: 506-61-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- POTASSIUM SILVER CYANIDE
CAS Registry Number: 506-61-6
Synonyms: Argentate(l-), bis(Cyano-C)-, Potassium; Argentate(l-), Dicyano-,
Potassium; Argentates(I) (Sol), Dicyano-; Potassium Argentocyanide; Potassium
bis(Cyano-C)Argentate(l-); Potassium Dicyanoargentate; Potassium
Dicyanoargentate (KAg(CN)2); Potassium Dicyanoargentate(l-); Potassium
Dicyanoargentate(I); Potassium Silver Cyanide (KAg(CN)2); Silver Potassium
Cyanide [AgK(CN)2]
Chemical Formula: C2AgN2'K
Molecular Weight: 199.01
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 21 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): In Cyanide Compounds and Silver
Compounds categories
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 2.36 at 25°C (*Hawley 1977)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Merck 1976)
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CAS Registry Number: 506-61-6
Page 2 of 4
POTASSIUM SILVER CYANIDE
SECTION II (continued)
Appearance and Odor: White crystals (*Merck 1976)
SECTION HI -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: (Cyanides) TWA 5 mg/ms, as cyanide (skin) (AGCIH 1986-87, p.14)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): The primary health hazard
is as a cyanide (*Gosselin 1976). (Non-specific -- Cyanide, Inorganic,
n.o.s.). It is poisonous and may be fatal if inhaled, swallowed or
absorbed through the skin. Fire may produce irritating or poisonous gases
(DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV « FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Cyanide, Inorganic, n.o.s.) Use
dry chemical, carbon dioxide, water spray, or foam for small fire, and
water spray, fog, or foam for large fires. Move containers of this
material away from fire area if this can be done without risk (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Cyanide, Inorganic,
n.o.s.) Isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Wear positive
pressure breathing apparatus and special protective clothing. Fight fire
from maximum distance. Dike fire control water for later disposal. Do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition,
potassium silver cyanide emits very toxic fumes of cyanide and nitrogen
oxides (Sax 1984, p. 2282).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 506-61-6
Page 3 of 4
POTASSIUM SILVER CYANIDE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Light (*Merck 1976)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition,
potassium silver cyanide emits very toxic fumes of cyanide and nitrogen
oxides (Sax 1984, p. 2282).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Potassium silver cyanide is used in silver plating, as a bactericide
(*Merck 1976), and in the manufacture of antiseptics (*Hawley 1977). Not
registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation or skin contact (see Section III above). (Non-Specific --
Cyanide, Inorganic, n.o.s.) Do not touch spilled materials; stop leak if
you can do so without risk. Use water spray to reduce vapors. Small
spills: absorb with sand or other noncombustible absorbent material and
place into containers for later disposal. Small dry spills: with clean
shovel place material into clean, dry container and cover; move containers
from spill area. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 506-61-6
Page 4 of 4
POTASSIUM SILVER CYANIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: As a cyanide, massive doses may produce,
without warning, sudden loss of consciousness and prompt death from
respiratory arrest. Smaller but still lethal doses result in illness that
may be prolonged for 1 or more hours. Other symptoms may include numbness
in throat, salivation, nausea, anxiety, dizziness, irregular breathing,
odor of bitter almonds may be noted on breath, blood pressure may rise,
slowing of the heart beat, sensation of constriction in the chest,
unconsciousness followed by violent convulsions and paralysis (*Gosselin
1976).
Emergency and First Aid Procedures: (Non-Specific -- Cyanide, Inorganic,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
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CAS Registry Number: 506-68-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CYANOGEN BROMIDE
CAS Registry Number: 506-68-3
Synonyms: Bromine Cyanide; Bromocyan; Bromocyanide; Bromocyanogen; Campilit;
Cyanobromide; Cyanogen Monobromide; TL 822
Chemical Formula: CBrN
Molecular Weight: 105.93
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(human) 0.398 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 142°F, 61.4°C (*Weast 1979)
Specific Gravity (H2O=1): 2.015 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 92 at 20°C (*Patty 1963)
Melting Point: 126°F, 52°C (*Merck 1976)
Vapor Density (AIR=1): 3.62 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Weast 1979)
Appearance and Odor: Colorless to white cubes or needle-like crystals
with a penetrating odor (*Merck 1976; *Sax 1979; *NFPA 1978; *Patty 1963)
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CAS Registry Number: 506-68-3
Page 2 of 4
CYANOGEN BROMIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: (Cyanides) TWA 5mg/m3, as cyanide (skin) (ACGIH 1986-87, p. 14)
IDLH: Not Found
Other Limits Recommended: Suggested TLV less than 0.5 ppm (*Patty 1963).
Routes of Entry: Inhalation: Yes (*NIOSH 1979)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Super toxic; probable oral
lethal dose in humans is less than 5 mg/kg or a taste (less than 7 drops)
for a 70 kg (150 Ib.) person (*Gosselin 1976). Vapors are highly irritant
and very poisonous (*Merck 1976).
Medical Conditions Generally Aggravated by Exposure: Individuals with
chronic diseases of the kidneys, respiratory tract, skin, or thyroid are at
greater risk of developing toxic cyanide effects (*Encyc Occupat Health and
Safety 1983).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Noncombustible (NFPA 1978, p. 49-34)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish fire using agent suitable for type of
surrounding fire. Material itself does not burn or burns with difficulty.
Use foam, carbon dioxide, or dry chemical. Cool all affected containers
with flooding quantities of water. Do not use water on material itself.
If large quantities of combustibles are involved, use water in flooding
quantities as spray and fog. Use water spray to absorb vapors. Keep
material out of water sources and sewers. Use water spray to knock down
vapors (Student 1981, p. 158).
Special Fire Fighting Procedures: Wear full protective clothing. Avoid
direct water contact as it will cause cyanogen bromide to decompose,
releasing toxic gases (*NFPA 1978). Avoid breathing vapors or dusts; keep
upwind; wear self-contained breathing apparatus (Student 1981, p. 158).
Unusual Fire and Explosion Hazards: Cyanogen bromide is not combustible
itself, but impure cyanogen bromide decomposes rapidly and tends to explode
(*Merck 1976). A violent reaction may take place on contact with large
quantities of acid (*NFPA 1978). Vapors are highly irritating (*Merck
1976).
NFPA Flammability Rating: 0
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CAS Registry Number: 506-68-3
Page 3 of 4
CYANOGEN BROMIDE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes, impure material decomposes rapidly and tends
to explode (*Merck 1976)
Stable:
Conditions to Avoid: Avoid physical damage, contact with acids or
water, and store away from a location where water may be needed for
fire control (*NFPA 1978).
Incompatibility (Materials to Avoid): Water, acids (*NFPA 1978)
Hazardous Decomposition or Byproducts: When material is heated to
decomposition, it emits very toxic fumes of cyanide and bromide (Sax 1984,
p. 825).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Cyanogen bromide is used in organic synthesis, as a fumigant, a pesticide,
in cellulose technology, and in gold-extraction (*Patty 1963). Not
registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do it without
risk. Use water spray to reduce vapors. Small spills: take up
with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 506-68-3
Page 4 of 4
CYANOGEN BROMIDE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 506-68-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
CYANOGEN BROMIDE
(506-68-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Cyanogen bromide toxicity can occur via ingestion, dermal/eye
contact, or inhalation; death may occur within minutes. IMMEDIATELY begin
administering 100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Forms - White cubes or needlelike crystals.
Odor - Penetrating.
Commercial Form - 97% pure solid.
Uses - Fumigant, chemical intermediate.
Materials to Avoid - Acids, water (except for use in emergency life support).
Other Names - Bromine cyanide, Bromocyan, Cyanobromide, TL-822.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulfate), sodium
bicarbonate, diazepam, phenytoin.
Signs and Symptoms of Acute Cyanogen Bromide Exposure:
Warning: Cyanogen bromide may be fatal if inhaled, swallowed, or absorbed
through skin or mucous membranes. Caution is advised.
Signs and symptoms of acute exposure to cyanogen bromide may include
hypertension (high blood pressure) and tachycardia (rapid heart rate), followed
by hypotension (low blood pressure) and bradycardia (slow heart rate). Cherry-
red or bloody mucous membranes may be noted. Cardiac arrhythmias and other
cardiac abnormalities are common. Cyanosis (blue tint to the skin and mucous
membranes) may be observed,?
-------
EFATG
CAS Registry Number: 506-68-3
Page 2 of 3
CYANOGEN BROMIDE
Headache, vertigo (dizziness), agitation, and giddiness may be followed by
combative behavior, convulsions, paralysis, protruding eyeballs, dilated and
unreactive pupils, and coma. Tachypnea (rapid, shallow respirations) or
hyperpnea (rapid, deep respirations) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may also occur.
Cyanogen bromide is irritating to the skin, eyes, and mucous membranes.
Lacrimation (tearing) and a burning sensation of the mouth and throat are
common. Salivation, nausea, and vomiting may also occur.
Emergency Life-Support Procedures:
Acute exposure to cyanogen bromide may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to cyanogen bromide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with cyanogen bromide-
contaminated persons or their gastric contents can result in self-
poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to cyanogen bromide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin : , - ristering 100% oxygen to
all victims. Monitor victims for respiratory cL
-------
EFATG
CAS Registry Number: 506-68-3
Page 3 of 3
CYANOGEN BROMIDE
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with cyanogen bromide-
contaminated persons or their gastric contents can result in self-
poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with cyanogen bromide-
contaminated persons or their gastric contents can result in self-
poisoning.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. DO NOT induce vomiting or attempt to neutralize!
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 506-78-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CYANOGEN IODIDE
CAS Registry Number: 506-78-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 545): Iodine Cyanide;
Jodcyan
Chemical Formula: CIN
Molecular Weight: 152.92
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(cat) 18 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 2.84 (Hawley 1981, p. 295)
Vapor Pressure (mmHg): 1 at 25.2°C (Sax 1984, p. 826)
Melting Point: 295.7°F, 146.5°C (Hawley 1981, p. 295)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly (Weast 1980, p. C-259)
Appearance and Odor: White needles with a very pungent odor (Merck 1983,
p. 385).
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CAS Registry Number: 506-78-5
Page 2 of 4
CYANOGEN IODIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: (Cyanides) TWA 5.0 mg/m8, as cyanide (skin) (ACGIH 1986-87,
P. 14)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: No (Merck 1983, p. 385)
Skin: Yes (Sax 1984, p. 826, p. 822)
Ingestion: Yes (Sax 1984, p. 826, p. 822)
Health Hazards (Acute, Delayed, and Chronic): Causes convulsions,
paralysis and death from respiratory failure (Merck 1983, p. 385). Highly
toxic; strong irritant to eyes and skin (Hawley 1981, p. 295).
(Non-Specific -- Cyanide or Cyanide Mixture, Dry): Poisonous, may be fatal
if swallowed or absorbed through skin. Contact may cause burns to the skin
and eyes. Fire may produce irritating or poisonous gases (DOT 1984, Guide
55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Cyanide or Cyanide Mixture, Dry)
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam. Move container from fire area if you
can do so without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Cyanide or Cyanide
Mixture, Dry) Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, cyanide, and iodide (Sax 1984,
p. 826).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 506-78-5
Page 3 of 4
CYANOGEN IODIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Phosphorus (Sax 1984, p. 826)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, cyanide, and iodide (Sax 1984,
p. 826).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Taxidermists' preservatives (Hawley 1981, p. 295). Generally for
destroying all lower forms of life (Merck 1983, p. 385).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Cyanide or Cyanide Mixture, Dry) Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel, place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death due to respiratory
failure (Merck 1983, p. 385). Health effects are similar to cyanides and
iodides (Sax 1984, p. 826). Upon ingestion, a bitter, acrid, burning taste
is sometimes noted. Other symptoms are anxiety, confusion, dizziness,
giddiness, rapid and difficult breathing, palpitations, tightness in chest,
unconsciousness, violent convulsions and death (Gosselin 1984, p. HI-127).
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CAS Registry Number: 506-78-5
Page 4 of 4
CYANOGEN IODIDE
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific -- Cyanide or Cyanide
Mixture, Dry) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
NIOSH/OSHA 1978
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety. 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
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CAS Registry Number: 509-14-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TETRANITROMETHANE
CAS Registry Number: 509-14-8
Synonyms: Methane, Tetranitro; NCI-C55947; Tetan; TNM
Chemical Formula: CN4O8
Molecular Weight: 196.04
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.144 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 259°F, 126°C (*Merck 1976)
Specific Gravity (H2O=1): 1.6380 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 13 at 25°C (*Patty 1963)
Melting Point: 57.6°F, 14.2°C (*Weast 1979)
Vapor Density (AIR=1): 6.8 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor: Pale yellow liquid (*Merck 1976) or colorless oily
fluid with acrid biting odor (*Patty 1963), causes tears (NIOSH/OSHA 1978,
p. 178).
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CAS Registry Number: 509-14-8
Page 2 of 4
TETRANITROMETHANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 ppm (8 mg/m3) (NIOSH 1987, p. 222)
ACGIH TLV: TWA 1 ppm (8 mg/ms) (*ACGIH 1980)
IDLH: 5 ppm (NIOSH/OSHA 1978, p. 178)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Patty 1963)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Patty 1963)
Health Hazards (Acute, Delayed, and Chronic): Acute effects include
irritation of the eyes and respiratory passages and mild burns to the skin
(*Sax 1975). After more prolonged inhalation, headache and respiratory
distress may occur (*Patty 1963). After prolonged exposure, central
nervous system, heart, liver, and kidney damage can occur as well as
pulmonary edema (*ACGIH 1980; *Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Non-combustible (NIOSH/OSHA 1978, p. 178)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish small fires with water only, no dry
chemicals or carbon dioxide. For large fires, flood the fire area with
water (DOT 1984, Guide 47).
Special Fire Fighting Procedures: Do not move cargo or vehicle if cargo
has been exposed to heat. Cool containers that are exposed to flames with
water from the side until well after fire is out. For massive fire, use
unmanned hose holder or monitor nozzles; if this is impossible, withdraw
from area and let fire burn (DOT 1984, Guide 47).
Unusual Fire and Explosion Hazards: Spontaneous chemical reaction may
produce fire. Material is a strong oxidizer. The potential for explosion
is severe, especially when exposed to heat or to powerful oxidizing or
reducing agents; or when shocked or heated (*Sax 1975). It is more easily
detonated than TNT (*Patty 1963). Impurities can also cause explosion
(*Merck 1976). The material is highly sensitive; hydrocarbons exposed to
it form exceedingly sensitive explosives (*NFPA 1978).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 509-14-8
Page 3 of 4
TETRANITROMETHANE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Sax 1975)
Stable:
Conditions to Avoid: Impurities, shock, heat, and reducing agents
(*Sax 1975)
Incompatibility (Materials to Avoid): Hydrocarbons, aluminum, toluene,
cotton, aromatic nitro compounds (Sax 1984, p. 2550); alkalis, metals
(NIOSH/OSHA 1978, p. 178); and rubber (Merck 1983, p. 1321).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of oxides of nitrogen. Shock will explode it
(*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur:. Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
It is proposed as an irritant war gas (*Merck 1976). It is used as an
oxidizing agent in rocket propellants; explosives; diesel fuel additives;
and a reagent for detecting double bonds (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Remove all ignition sources. Ventilate area of spill or leak. Collect for
reclamation or absorb in vermiculite, dry sand, earth or a similar
material. Avoid shock and friction if liquid spills on combustible
material such as wood, or paper (*NIOSH/OSHA 1981). Use water spray to
reduce vapors. Flush area with flooding amounts of water and dike spill
for later disposal. Keep unnecessary people away; isolate hazard area and
deny entry. Stay upwind; keep out of low areas (DOT 1984, Guide 47).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 509-14-8
Page 4 of 4
TETRANITROMETHANE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include burning eyes, skin, and
mucous membranes (*Sax 1975); headache, difficulty in breathing, and
dizziness. Skin contact results in bluish discoloration of skin and mucous
membranes (cyanosis), and skin burns (NIOSH/OSHA 1978, p. 179). Chronic
signs and symptoms included weariness, and pneumonia (*ACGIH 1980).
Emergency and First Aid Procedures: Exposed skin should be washed twice
with soap and water. Flush eyes with water at least 15 minutes (*Rumack
1975 to Present).
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CAS Registry Number: 514-73-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DITHIAZANINE IODIDE
CAS Registry Number: 514-73-8
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 664): Benzothiazolium,
3-Ethyl-2-(5-(3-Ethyl-2-Benzothiazolinylidene)-l,3-Pentadienyl)-, Iodide;
Abminthic; Anelmid; Delvex; 3,3'-Diethylpentamethinethiacyanine Iodide;
Dilombrin; 3,3'-Diethylthiadicarbocyanine Iodide; L-01748; Omni-Passin; Partel;
Telmid; Vercidon; 3-Ethyl-2-(5-(3-Ethyl-2-Benzothiazolylidene)-
l,3-Pentadienyl)benzothiazolium Iodide; Anguifugan; Dejo; Deselmine; Dizan;
Nectocyd; Telmicid (Merck 1983, p. 492)
Chemical Formula: C23H24N2S2I
Molecular Weight: 519.51
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposes at 248°C (Merck 1983, p. 492)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Inseluble (Merck 1983, p. 492)
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CAS Registry Number: 514-73-8
Page 2 of 4
DITHIAZANINE IODIDE
SECTION II (continued)
Appearance and Odor: Green, needle-like crystals (Merck 1983, p. 492).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1024)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by mouth (Sax
1984, p. 1024). (Non-Specific - Pesticide, Solid, n.o.s.) Poisonous if
swallowed, or if dust is inhaled (DOT 1984, Guide 53).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do it
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Pesticide, Solid,
n.o.s.) This material may burn but does not ignite readily. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Wear self-contained, postive pressure if available,
breathing apparatus and full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of iodine, sulfur oxides, and nitrogen oxides (Sax 1984,
p. 1024).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 514-73-8
Page 3 of 4
DITHIAZANINE IODIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of iodine, sulfur oxides, and nitrogen oxides (Sax 1984,
p. 1024).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Veterinary anthelmintic, sensitizer for photographic emulsions (Merck 1983,
p. 492) and for insecticides (Farm Chemicals Handbook 1984, p. C-85).
Not registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other non-combustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a "fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 514-73-8
Page 4 of 4
DITHIAZANINE IODIDE
COMMENTS
_ Sources searched but no information found:
Weast 1979
Hawley 1981
ACGIH 1984
NIOSH/OSHA 1978
Weiss 1980
Gosselin 1984
Hayes 1982
Buchel 1983
Encyc Occupat Health and Safety 1983
-------
CAS Registry Number: 534-07-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BIS(CHLOROMETHYL) KETONE
CAS Registry Number: 534-07-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 325) 2-Propanone,
1,3-Dichloro-; sym-Dichloroacetone; alpha,alpha'-Dichloroacetone;
alpha,gamma-Dichloroacetone; 1,3-Dichloroacetone; l,3-Dichloro-2-Propanone
Chemical Formula: CSH4C12O
Molecular Weight: 126.97
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.027 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 343°F, 173°C (Merck 1983, p. 443)
Specific Gravity (H2O=1): 1.3826 at 46°C/4°C (Merck 1983, p. 443)
Vapor Pressure (mmHg): Not Found
Melting Point: 113°F, 45°C (Merck 1983, p. 443)
Vapor Density (AIR=1): 4.38 (Sax 1984, p. 464)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Merck 1983, p. 443)
Appearance and Odor: Crystalline solid (Merck 1983, p. 443)
-------
CAS Registry Number: 534-07-6
Page 2 of 4
BIS(CHLOROMETHYL) KETONE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 464)
Skin: Yes (DOT 1984, Guide 55)
Ingestion: Yes (Sax 1984, p. 464)
Health Hazards (Acute, Delayed, and Chronic): It may be fatal if inhaled,
swallowed or absorbed through skin. Contact may cause burns to skin and
eyes. Fire may produce irritating or poisonous gases. Runoff from fire
control water may give off poisonous gases. Runoff from fire control or
dilution water may cause pollution (DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam.
Move container from fire area if you can do so without risk. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site. If water pollution occurs, notify appropriate
authorities (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes of chlorides (Sax 1984, p. 464). This material
may burn but does not ignite readily. Container may explode in heat of
fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 534-07-6
Page 3 of 4
BIS(CHLOROMETHYL) KETONE
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of chlorides (Sax 1984, p. 464).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Formerly extensively used in textiles (especially polyester fabrics) and
still employed in polyurethane foams, textile backcoating and adhesives
(Gosselin 1984, p. 11-303).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation. In case of contact, immediately flush skin or eyes with
water (see Section III above). Do not touch spilled material; stop leak
if you can do so without risk. Use water spray to reduce vapors. For
small spills, absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. For large spills, dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: It causes tearing and blistering (Merck
1983, p. 443).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
-------
CAS Registry Number: 534-07-6
Page 4 of 4
BIS(CHLOROMETHYL) KETONE
SECTION IX (continued)
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
-------
CAS Registry Number: 534-52-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DINITROCRESOL
CAS Registry Number: 534-52-1
Synonyms: 4,6-Dinitro-o-Cresol; 2,4-Dinitro-6-Methylphenol;
2-Methyl-4,6-Dinitrophenol; 3,5-Dinitro-2-Hydroxytoluene;
6-Methyl-2,4-Dinitrocresol; Antinonin; Antinonnin; Arborol; Capsine; Chemsect
DNOC; Degrassan; Dekrysil; Detal; Dillex; Dinitro; Dinitro-o-Cresol;
Dinitrodendtroxal; Dinitrol; Dinitromethyl Cyclohexyltrienol; Dinitrosol;
Dinoc; Dinurania; Ditrosol; DN; DN-Dry Mix No. 2; DNC; DNOC; Effusan 3436;
Elgetol; Elgetol 30; Elipol; ENT 154; Extrar; Hedolit; K III; K IV; Krenite;
Kreozan; Kresamone; Krezotol 50; Sandolin A; Selinon; Toluene,
3,5-Dinitro-2-Hydroxy-; Phenol, 2-methyl-4,6-dinitro
Chemical Formula: C7H6N2O5
Molecular Weight: 198.13
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 594°F, 312°C (ACGIH 1980, p. 152)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00005 (NIOSH/OSHA 1978, p. 90)
Melting Point: 190°F, 87.5°C (*Merck 1976)
Vapor Density (AIR=1): 6.82 (Sax 1984, p. 1212)
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 534-52-1
Page 2 of 3
DINITROCRESOL
SECTION II (continued)
Solubility in Water: 0.01 g in 100 ml (NIOSH/OSHA 1978, p. 90)
Appearance and Odor: Yellow odorless solid (NIOSH/OSHA 1978, p. 90;
*Spencer 1982)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 200 mg/m3 (NIOSH 1987, p. 110)
ACGIH TLV: TWA 0.2 mg/m3 (skin) (ACGIH 1986-87, p. 17)
IDLH: 5 mg/m3 (NIOSH/OSHA 1980, p. 90)
Other Limits Recommended: NIOSH: 0.2 mg/m3 10-hour TWA (NIOSH 1987, p.110)
Routes of Entry: Inhalation: Yes (ACGIH 1980, p. 152)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic material;
probable oral lethal dose is 5-50 mg/kg in humans or between 7 drops and 1
teaspoonful for a 70 kg (150 Ib.) person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): None (NIOSH/OSHA 1978, p. 90)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Water, foam, dry chemical, carbon dioxide (*CHRIS
1980)
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area. Stay upwind and keep out of low areas. Wear self-contained
breathing apparatus and full protective clothing. Move container from fire
area if you can do so without risk (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: It is explosive and is usually
moistened with up to 10 percent water to reduce the hazard (*Spencer 1982).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found .-
-------
CAS Registry Number: 534-52-1
Page 3 of 3
DINITROCRESOL
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
4,6-Dinitro-o-cresol is used as a spray to kill insect eggs on fruit trees,
as an herbicide, and as an insecticide (Hawley 1981, p. 374).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if it can be done without risk.
Take up small spills with sand or other noncombustible absorbent material;
place into containers for later disposal. Small dry spills may be shoveled
into clean, dry containers and covered. Larger spills should be diked for
later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 534-52-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
DINITROCRESOL
(534-52-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Yellow prisms or needles.
Odor - None.
Commercial Forms - 95 to 98% pure solid usually mixed with 10% water, paste
(with ammonium sulfate), or solution in petroleum oil.
Uses - Herbicide, insecticide, dyestuff industry.
Materials to Avoid - Metals.
Other Names - Antinonin, Arborol, Capsine, Degrassan, Detal, Dillex, Dinitro,
4,6-dinitro-o-cresol, Dinoc, Elgetol, Krenite, Kreozan, 2-methyl-4,6-
dinitrophenol, Selinon.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital.
Signs and Symptoms of Acute Dinitrocresol Exposure:
Warning: Effects may be delayed for several hours. Toxicity of dinitrocresol
is enhanced by high ambient temperature and physical activity. Caution is
advised.
Early manifestations of acute dinitrocresol exposure include fever, sweating,
headache, and confusion. Blood pressure, pulse, and respiratory rate are often
elevated. Severe exposure may result in restlessness, seizures, and coma.
Other signs and symptoms include dyspnea (shortness of breath), cyanosis (blue
tint to skin and mucous membranes), pulmonary edema, nausea, vomiting, and
abdominal pain. Liver injury with associated jaundice, kidney failure, and
-------
EFATG
CAS Registry Number: 534-52-1
Page 2 of 3
DINITROCRESOL
cardiac arrhythmias are commonly noted. Dermal exposure results in yellow
staining of the skin and may produce burns. Dinitrocresol may irritate and
burn the eyes and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to dinitrocresol may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dinitrocresol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dinitrocresol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 534-52-1
Page 3 of 3
DINITROCRESOL
Ingestion Exposure:
\. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. DO NOT induce vomiting.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. RUSH to a health care facility.
-------
CAS Registry Number: 535-89-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ CRIMIDINE
CAS Registry Number: 535-89-7
Synonyms: Pyrimidine, 2-Chloro-4-(DimethyIamino)-6-Methyl-; 2-Chloro-4-
Dimethylamino-6-Methyl-Pyrimidine; 2-Chloro-4-Methyl-6-Dimethylaminopyrimidine;
2-Chloro-N,N-6-Trimethyl-4-Pyrimidinamine; 4-Pyrimidinamine, 2-Chloro-N,N,6-
trimethyl-; Castrix; W 491
Chemical Formula: C7H10N3C1
Molecular Weight: 171.65
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 1.2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 284-297°F, 140-147°C at 4 mmHg (*Weast 1974)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Less than 10-5 at 20°C (*Hartley 1983)
Melting Point: 189°F, 87°C (*Weast 1974)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.936 g/100 mL at 20°C (*Hartley 1983)
Appearance and Odor: Brown waxy solid (*Weast 1974); colorless crystals
(*Hartley 1983)
-------
CAS Registry Number: 535-89-7
Page 2 of 4
CRIMIDINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): Super toxic; probable oral
lethal dose in humans is less than 5 mg/kg or less than 7 drops for a 70 kg
(150 Ib.) person (*Gosselin 1984). May cause serious central nervous
system damage leading to convulsions (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
for fumes (*Hartley 1983).
Unusual Fire and Explosion Hazards: It emits highly toxic fumes when
heated to decomposition (*Sax 1975).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes, very stable in neutral medium (*Hartley 1983)
Conditions to Avoid: Decomposing heat (*Sax 1975)
Incompatibility (Materials to Avoid): Acids and acid fumes (*Sax 1975)
Hazardous Decomposition or Byproducts: It emits highly toxic chloride
fumes when heated to decomposition (*Sax 1975)
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CAS Registry Number: 535-89-7
Page 3 of 4
CRIMIDINE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a rodenticide (*Merck ]983). Not registered as a pesticide
in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do so without
risk. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal. If water pollution occurs,
notify appropriate authorities (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may result in serious central
nervous system damage leading to convulsions that may be fatal (*Merck
1976). Symptoms include restlessness; apprehension; muscular stiffness;
sensitivity to light, noises, and contact; and cold sweat. If patient
survives 5 to 6 hours there may not be serious problems (*Gosselin 1984).
-------
CAS Registry Number: 535-89-7
Page 4 of 4
CRIMIDINE
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 538-07-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHYLBIS(2-CHLOROETHYL)AMINE
CAS Registry Number: 538-07-8
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 818): Triethylamine,
2,2'-Dichloro-; bis(2-Chloroethyl)Ethylamine; Ethylbis(beta-Chloroethyl)Amine;
Ethyl-S; HN1; TL 329
(U.S. Army 1975 Synonyms, p. 3-9): Nitrogen Mustard; HN-1
Chemical Formula: C6H13C12N
Molecular Weight: 170.10
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 dermal
(mouse) 13 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 185°F, 85°C at 12 mmHg (Merck 1983, p. 683)
Specific Gravity (H2O=1): 1.0861 at 23°C/4°C (Merck 1983, p. 683)
Vapor Pressure (mmHg): 0.24 at 25°C (U.S. Army 1975, p. 3-9)
Melting Point: -29°F, -34°C (Merck 1983, p. 683)
Vapor Density (AIR=1): 5.9 (U.S. Army 1975, p. 3-9)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (Merck 1983, p. 683)
Appearance and Odor: Liquid with a faint, fishy amine odor (Merck 1983,
p. 683).
-------
CAS Registry Number: 538-07-8
Page 2 of 4
ETHYLBIS(2-CHLOROETHYL)AMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 458)
Skin: Yes (Sax 1984, p. 458)
Ingestion: Yes (Sax 1984, p. 458)
Health Hazards (Acute, Delayed, and Chronic): This compound is a nitrogen
mustard. It is highly irritating to skin, eyes, and mucous membranes
(Merck 1983, p. 683). Nitrogen mustards have preferential toxicity for
rapidly dividing cells. Workers exposed briefly to estimated
concentrations of 10-100 ppm by inhalation became severely ill (Encyc
Occupat Health and Safety 1983, p. 462). The median lethal dosage is 1,500
mg-minute/m3 (U.S. Army 1975, p. 3-9).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): High enough not to interfere with military use
of the agent (U.S. Army 1975, p. 3-9).
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and chlorides (Sax 1984, p. 458).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (U.S. Army 1975, p. 3-9)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and chlorine (Sax 1984, p. 458).
-------
CAS Registry Number: 53&-07-8
Page 3 of 4
ETHYLBIS(2-CHLOROETHYL)AMINE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Polymerizes slowly (U.S. Army 1975, p. 3-10).
(Hazard not specified.)
SECTION VI -- USE INFORMATION
Delayed-action, military casualty agent (U.S. Army 1975, p. 3-10)
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
(Non-Specific -- Poisonous Liquid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent
material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
.*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Irritates the eyes in quantities which do
not significantly damage the skin or respiratory tract, insofar as single
exposures are concerned. After mild vapor exposure, there may be no skin
lesions. After severe vapor exposures, or after exposure to the liquid,
erythema may appear. Irritation and itching may occur. Later, blisters
may appear in the erythematous areas. Effects on the respiratory tract
include irritation of the nose and throat, hoarseness progressing to loss
of voice, and a persistent cough. Fever, labored respiration, and moist
rales develop. Bronchial pneumonia may appear after the first 24 hours.
Following ingestion or systemic absorption, material causes inhibition of
cell mitosis, resulting in depression of the blood-forming mechanism and
-------
CAS Registry Number: 538-07-8
Page 4 of 4
ETHYLBIS(2-CHLOROETHYL)AMINE
SECTION IX (continued)
injury to other tissues. Severe diarrhea, which may be hemorrhagic,
occurs. Lesions are most marked in the small intestine and consist of
degenerative changes and necrosis in the mucous membranes. Ingestion of 2
to 6 milligrams causes nausea and vomiting (U.S. Army 1975, p. 3-9).
Emergency and First Aid Procedures: (Non-Specific — Nitrogen Mustards)
Stop exposure and treat symptomatically (Oilman 1985, p. 1257).
(Non-Specific — Poisonous Liquid, n.o.s.) Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Weast 1979
Hawley 1981
-------
CAS Registry Number: 541-25-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - LEWISITE
CAS Registry Number: 541-25-3
Synonyms: Arsine, Dichloro(2-Chlorovinyl)-; Arsine, (2-Chlorovinyl)
.Dichloro-; Arsonous Bichloride, (2-Chloroethenyl)- (90); Chlorovinylarsine
Dichloride; beta-Chlorovinylbichloroarsine; 2-Chlorovinyldichloroarsine;
Dichloro(2-Chlorovinyl)Arsine
Chemical Formula: C2H2AsCls
Molecular Weight: 207.31
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 dermal
(rabbit) 6 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 374°F, 190°C (decomposes) (Merck 1983, p. 445)
Specific Gravity (H2O=1): 1.888 at 20°C/4°C (Merck 1983, p. 445)
Vapor Pressure (mmHg): 0.395 at 20°C (Merck 1983, p. 445)
Melting Point: 32°F, 0.1°C (Merck 1983, p. 445)
Vapor Density (AIR=1): 7.1 (U.S. Army 1975, pp. 3-11, 3-12)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Merck 1983, p. 445)
Appearance and Odor: Liquid with odor of geraniums (Merck 1983, p. 445).
-------
CAS Registry Number: 541-25-3
Page 2 of 4
LEWISITE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 500 mg/ms as arsenic (NIOSH/RTECS 1982, p. 442)
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found *
Routes of Entry: Inhalation: Yes (Sax 1984, p. 783)
Skin: Yes (Sax 1984, p. 783)
Ingestion: Yes (Sax 1984, p. 783)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by all routes
of exposure. Lethal dose in humans is 6 ppm (inhalation), 20 mg/kg (skin)
(Sax 1984, p. 783). Eye injury below 300 mg-min./ms. It is a blister
agent, cell irritant, and systemic poison (U.S. Army 1975, pp. 3-11, 3-12).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): None (U.S. Army 1975, pp. 3-11, 3-12)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Arsenic Compound, Liquid, n.o.s.)
Extinguish with dry chemical, carbon dioxide, water spray, or foam. Use
water spray, fog, or foam for large fires (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Arsenic Compound,
Liquid, n.o.s.) Wear special protective clothing and positive pressure
breathing apparatus (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Arsenic Compound,
Liquid, n.o.s.) Container may explode in heat of fire. Fire may produce
irritating and poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzed by alkalies; neutralized
by sodium hypochlorite (Merck 1983, p. 445).
Hazardous Decomposition or Byproducts: Not Found
-------
CAS Registry Number: 541-25-3
Page 3 of 4
LEWISITE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Vesicant war gas; chemical warfare agent (Doull 1980, p. 279).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid contact with eyes and skin; avoid breathing vapors (see Section III
above). (Non-Specific -- Arsenic Compound, Liquid, n.o.s.) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
Can be decontaminated by supertropical bleach, DS2, or caustic soda (U.S.
Army 1975, pp. 3-11, 3-12).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This material causes pulmonary edema,
diarrhea, restlessness, weakness, subnormal temperature and low blood
pressure. It produces an immediate searing sensation in the eye, and
permanent loss of sight if not decontaminated within 1 minute. It produces
an immediate and strong stinging sensation to the skin, followed by
reddening within 30 minutes and blistering after about 13 hours.
Inhalation of high concentrations may be fatal in as short a time as 10
minutes (U.S. Army 1975, pp. 3-11, 3-12).
Emergency and First Aid Procedures: (Non-Specific — Arsenic Compound,
Liquid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. Remove and isolate contaminated clothing and shoes at the
site. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Keep victim quiet and maintain
-------
CAS Registry Number: 541-25-3
Page 4 of 4
LEWISITE
SECTION IX (continued)
normal body temperature. Effects may be delayed; keep victim under
observation. Speed in removing material from skin is of extreme importance
(DOT 1984, Guide 55).
-------
CAS Registry Number: 541-53-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DITHIOBIURET
CAS Registry Number: 541-53-7
Synonyms: Biuret, 2,4-Dithio-; Imidodicarbonimidothioic Diamide;
Imidodicarbonodithioic Diamide; Thioimidodicarbonic Diamide; DTB; Urea,
2-thio-l-(thiocarbamoyl)-
Chemical Formula: C2H5N3S2
Molecular Weight: 135.22
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.522 at 30°C (Merck 1983, p. 493)
Vapor Pressure (mmHg): Not Found
Melting Point: 358°F, 181°C (decomposes) (Merck 1983, p. 493)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.27 g/100 mL at 27°C (Merck 1983, p. 493)
Appearance and Odor: Crystalline solid (Merck 1983, p. 493)
-------
CAS Registry Number: 541-53-7
Page 2 of 3
DITHIOBIURET
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1257)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1257)
Health Hazards (Acute, Delayed, and Chronic): The material is highly
toxic. It may cause respiratory failure (Merck 1983, p. 493).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Dithiocarbamate Pesticide, Solid,
n.o.s.) Extinguish fire using agent suitable for type of surrounding fire.
(Material itself does not burn or burns with difficulty.) Use water in
flooding quantities as fog. Use alcohol foam, carbon dioxide or dry
chemical (Student 1981, p. 213).
Special Fire Fighting Procedures: (Non-Specific — Dithiocarbamate
Pesticide, Solid, n.o.s.) Wear boots, protective gloves, goggles and
self-contained breathing apparatus (Student 1981, p. 213).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes of oxides of sulfur and nitrogen (Sax 1984, p.
1257).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 541-53-7
Page 3 of 3
DITHIOBIURET
SECTION V (continued)
Hazardous Decomposition or Byproducts: Sulfur oxides and nitrogen oxides
are formed when the material is heated to decomposition (Sax 1984, p.
1257).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as a plasticizer, as a rubber accelerator, and as an
intermediate in manufacturing of pesticides (Merck 1983, p. 493).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific ~ Dithiocarbamate Pesticide, Solid, n.o.s.) Keep sparks,
flames and other sources of ignition away. Keep material out of water
sources and sewers. Avoid breathing dusts and fumes from burning material.
Keep upwind; avoid bodily contact with the material. Do not handle
broken packages without protective equipment. Wash away any material
which may have contacted the body with copious amounts of water or soap
and water (Student 1981, p. 213).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include respiratory paralysis
(Merck 1983, p. 493).
Emergency and First Aid Procedures: (Non-Specific -- Dithiocarbamate
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 542-76-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPIONITRILE, 3-CHLORO-
CAS Registry Number: 542-76-7
Synonyms: 3-Chloropropanonitrile; l-Chloro-2-Cyanoethane;
3-Chloropropanenitrile; 3-Chloropropionitrile; beta-Chloropropionitrile;
Propanenitrile, 3-Chloro-; USAF A-8798
Chemical Formula: CSH4C1N
Molecular Weight: 89.53
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 347-349°F, 175-176°C (Weast 1983, p. C-477)
Specific Gravity (H2O=1): 1.1573 at 20°C (Weast 1983, p. C-477)
Vapor Pressure (mmHg): 5 at 46°C (*Patty 1963)
Melting Point: -60°F, -51°C (*Merck 1976)
Vapor Density (AIR=1): 3.0 (NFPA 1984, p. 325M-26)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 4.5 g/100 mL at 25°C (Merck 1983, p. 304)
Appearance and Odor: Colorless liquid with a characteristic acrid odor
(*Hawley 1977)
-------
CAS Registry Number: 542-76-7
Page 2 of 4
PROPIONITRILE, 3-CHLORO-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (*Hawley 1977)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): Toxic effects are a result
of systemic cyanide poisoning (*Merck 1976). (Non-Specific -- Cyanide)
Few poisons are more rapidly lethal. Average oral lethal dose for hydrogen
cyanide is approximately 60-90 mg (corresponds to 200 mg of potassium
cyanide). Cause of death is lack of oxygen to the body's cells (especially
the brain and heart) as a result of the chemical inhibiting cell enzymes
(Gosselin 1984, pp. Ill-1-24-125).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 168°F (CC) (*Hawley 1977; Sax 1984, p. 769)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Alcohol foam is recommended, but water spray can
be used because the material can be cooled below its flash point (NFPA
1984, p. 325M-26).
Special Fire Fighting Procedures: (Non-Specific -- Propionitrile) Wear
positive pressure breathing apparatus and special protective clothing.
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Toxic gas (hydrogen chloride) is
released when the compound is heated above 130°C (266°F) (*Merck 1976).
When heated to decomposition, it emits very toxic fumes of chlorine-
containing compounds and nitrogen oxides (Sax 1984, p. 769).
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 542-76-7
Page 3 of 4
PROPIONITRILE, 3-CHLORO-
SECTION V (continued)
Incompatibility (Materials to Avoid): Heat (*Merck 1976).
Hazardous Decomposition or Byproducts: Hydrogen chloride is a by-product
(*Merck 1976). Also, when heated to decomposition, it emits very toxic
fumes of chlorine-containing compounds and nitrogen oxides (Sax 1984, p.
769).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in pharmaceutical and polymer synthesis (*Merck 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Propionitrile) Do not touch spilled material; stop leak
if you can do so without risk. Use water spray to reduce vapors. Absorb
small spills with sand or other noncombustible absorbent material. Dike
far ahead of spill for later disposal. Isolate hazard area and deny entry.
Stay upwind (DOT 1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines",. 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 542-76-7
Page 4 of 4
PROPIONITRILE, 3-CHLC&O-
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Cyanide) Symptoms
include rapid and irregular breathing, anxiety, confusion, odor of bitter
almonds (on breath or vomitus), nausea, vomiting (if oral exposure),
irregular heart beat, a feeling of tightness in the chest, bright pink
coloration of the skin, sweating, protruding eyeballs, dilated pupils,
unconsciousness followed by convulsions, involuntary urination and
defecation, paralysis and respiratory arrest (heart will beat after
breathing stops) (Gosselin 1984, p. Ill-126-127).
Emergency and First Aid Procedures: (Non-Specific ~ Cyanide) Get
emergency medical treatment immediately. If victim has taken the substance
by ingestion (orally) and is not showing symptoms, give syrup of ipecac.
If there is exposure through skin contact, wash immediately with soap and
water. If severe skin contact, treat patient for oral or inhalation
exposure. Exposed eyes should be flushed copiously with water for at least
15 minutes. If the victim stops breathing before emergency medical
treatment is available, give artificial respiration or oxygen, but avoid
mouth to mouth respiration; also avoid contact with contaminated skin
(Gosselin 1984, p. III-127; *Rumack 1975 to Present).
-------
CAS Registry Number: 542-88-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLOROMETHYL ETHER
CAS Registry Number: 542-88-1
Synonyms: Bis(Chloromethyl) Ether; l,l'-Dichlorodimethyl Ether;
alpha.alpha'-Dichlorodimethyl Ether; BCME; bis-CME; Chloro(chloromethoxy)
Methane; Dichlorinated Methyl Oxide; Dichlorodimethyl Ether; Dichloromethyl
Ether; Dimethyl-l.l'-Dichloroether; Ether, bis(Chloromethyl); Monochloromethyl
Ether; Oxybis(Chloromethane); Sym-Dichloro-Dimethyl Ether; Sym-Dichloromethyl
Ether; Methane, Oxybis(chloro-
Chemical Formula: C2H4C12O
Molecular Weight: 114.97
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.025 mg/liter/6 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds) (statutory)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 223°F, 106°C (*Merck 1976)
Specific Gravity (H2O=1): 1.315 at 20°C (*Merck 1976)
Vapor Pressure (mmHg): 30 at 22°C (*Callahan 1979)
Melting Point: -42.7°F, -41.5°C (*Weast 1979)
Vapor Density (AIR=1): 4.0 (*Sax 1968)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not soluble; decomposes (Weast 1979, p. C-300)
-------
CAS Registry Number: 542-88-1
Page 2 of 4
CHLOROMITHYL ETHER
SECTION II (continued)
Appearance and Odor: Colorless liquid (*Merck 1976) with extremely
suffocating odor (*Sittig, 1981).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Occupational carcinogen, no permissible exposure limit (NIOSH
1987, Appendix C)
ACGIH TLV: TWA 0.001 ppm (0.005 mg/m3) (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: Human carcinogen — recommended TLV 0.001 ppm
(ACGIH 1984, p. 40).
Routes of Entry: Inhalation: Yes (Sax 1985, p. 463)
Skin: Yes (Sax 1985, p. 463)
Ingestion: Yes (Sax 1985, p. 463)
Health Hazards (Acute, Delayed, and Chronic): Acute toxicity is high by
ingestion, inhalation, and skin irritation. Small quantities may cause
death or permanent injury after very short exposure (*Sax 1968).
Chloromethyl ether is an alkylating agent which is a recognized human
carcinogen. There is a strong association between industrial exposure and
excess lung cancer (*Sittig 1981; *NIOSH 1984; *IARC 1972-85).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Less than 19°C (*Bretherick 1979)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Move container from fire area if you
can do so without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (*DOT 1984).
Unusual Fire and Explosion Hazards: Container may explode in heat of fire
(*DOT 1984).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 542-88-1
Page 3 of 4
CHLOROMETHYL ETHER
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1976)
Stable:
Conditions to Avoid: Avoid decomposing heat (Sax 1985, p. 63),
powerful oxidizers, areas of high fire hazard (*Sax 1975), and moist air
(*Merck 1976).
Incompatibility (Materials to Avoid): Water: hydrolyzes very rapidly
(half life 10-40 seconds) on contact with water (*Callahan 1979).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of chlorides (Sax 1985, p. 463). Decomposed by
water to hydrochloric acid and formaldehyde (*Merck 1976).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a research chemical and lab reagent (*Hawley 1977; *SRI). Not
produced commercially in the U.S. (*SRI), but was formerly used for
chloromethylation in industry (*ACGIH 1980). Has been used as an
alkylating agent in the manufacture of polymers (*Sittig 1981). May be
produced as chemical intermediate (*IARC 1972 - present).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Remove and isolate contaminated clothing
at the site. Spill or leak: do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spills for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 542-88-1
Page 4 of 4
CHLOROMETHYL ETHER
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Vapor is severly irritating to the skin
and mucous membranes and may cause cornea damage which may heal slowly
(*Sittig 1981).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed. Keep victim
under observation (*DOT 1984).
-------
CAS Registry Number: 542-90-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHYLTHIOCYANATE
CAS Registry Number: 542-90-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 743) Thiocyanic Acid,
Ethyl Ester; Ethane, Thiocyanato-; Ethyl Rhodanate; Ethyl Sulfocyanate
Chemical Formula: CSH5NS
Molecular Weight: 87.15
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(cat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 295°F, 146°C (Merck 1983, p. 1336)
Specific Gravity (H2O=1): 1.007 at 23°C/4°C (Merck 1983, p. 1336)
Vapor Pressure (mmHg): Not Found
Melting Point: -122°F, -85.5°C (Weast 1983, p. C-515)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Merck 1983, p. 1336)
Appearance and Odor: Liquid (Merck 1983, p. 1336).
-------
CAS Registry Number: 542-90-5
Page 2 of 4
ETHYLTHIOCYANATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1394)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic if ingested (Sax 1984, p. 1394).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Pesticide, Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Pesticide, Liquid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984, p.
1394).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 542-90-5
Page 3 of 4
ETHYLTHIOCYANATE
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984, p.
1394).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is an agricultural insecticide (Gosselin 1981, p. 11-288).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Pesticide, Liquid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
For small spills, absorb with sand or other noncombustible absorbent
material and place into containers for later disposal. For large spills,
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Toxicity hazard similar to thiocyanate
(Sax 1984, p. 1394). Prolonged absorption may produce various skin
eruptions, runny nose, and occasionally dizziness, cramps, nausea, vomiting
and mild or severe disturbances of the nervous system (Sax 1984, p. 2568).
Ethyl thiocyanate is an aliphatic thiocyanate (Gosselin 1981, p. 11-288).
Aliphatic thiocyanates have the following signs and symptoms. The
ingestion of a concentrated solution may lead to vomiting. The principal
systemic reaction is probably one of central nervous depression,
interrupted by periods of restlessness, abnormally fast and deep
respiratory movements and convulsions. Death is usually due to respiratory
arrest from paralysis of the medullary centers. In nonfatal cases injuries
to the liver and kidneys may appear (Gosselin 1981, p. 111-16).
Emergency and First Aid Procedures: Treatment is as for aliphatic
thiocyanates (Gosselin 1981, p. 11-288). Because cyanide is probably
largely responsible for poisonings, antidotal measures against cyanide
should be instituted promptly (Gosselin 1981, p. 111-16). First aid for
-------
CAS Registry Number: 542-90-5
Page 4 of 4
ETHYLTHIOCYANATE
SECTION IX (continued)
cyanide includes moving the victim to fresh air. Call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed, keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Hayes 1982
NFPA 1984
Farm Chemicals Handbook 1984
Buchel 1983
Hawley 1981
DASE 1980
Verschueren 1983
-------
CAS Registry Number: 555-77-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TRIS(2-CHLOROETHYL)AMINE
CAS Registry Number: 555-77-1
Synonyms: (SANSS 1983 SYNONYMS) Triethylamine, 2,2',2"-Trichloro-;
Trichlormethine; Tri-(2-Chloroethyl)Amine; 2,2',2"-Trichlorotriethylamine;
Tris(beta-chloroethyl)amine; TS 160; Ethanamine, 2-Chloro-N,N-bis
(2-Chloroethyl)-; HN 3; TL 145; 2-Chloro-N,N-bis(2-Chloroethyl)
Ethanamine
Chemical Formula: C6H12C1SN
Molecular Weight: 204.54
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(mouse) 0.35 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 493°F, 256°C calculated, decomposes (U.S. Army 1975, p.
3-10)
Specific Gravity (H2O=1): 1.2347 (Merck 1979, p. 1379)
Vapor Pressure (mmHg): 0.0109 at 25°C (U.S. Army 1975, p. 3-10)
Melting Point: 25°F, -4°C (Weast 1979, p. C-110)
Vapor Density (AIR=1): 7.1 (U.S. Army 1975, p. 3-10)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Weast 1979, p. C-110)
-------
CAS Registry Number: 555-77-1
Page 2 of 4
TRIS(2-CHLOROETHYL)AMINE
SECTION II (continued)
Appearance and Odor: Liquid with faint odor of fish and soap (Merck 1983,
p. 1379); no odor when pure (U.S. Army 1975, p. 3-10)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2691)
Skin: Yes (Sax 1984, p. 2691)
Ingestion: Yes (Sax 1984, p. 2691)
Health Hazards (Acute, Delayed, and Chronic): Most toxic of the nitrogen
mustards. The median lethal dose for inhalation is
1,500 mg-min/ms; for skin absorption (masked personnel) is
10,000 mg-min/m3. The medium incapacitating dose for eye injury is
200 mg-min/m3; for skin absorption is 2,500 mg-min/m3 (U.S. Army 1975, p.
3-10).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): High enough not to interfere with military use
of the agent (U.S. Army 1975, p. 3-10).
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
%
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (U.S. Army 1975, p. 3-10)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2691)
-------
CAS Registry Number: 555-77-1
Page 3 of 4
TRIS(2-CHLOROETHYL)AMINE
SECTION V (continued)
Incompatibility (Materials to Avoid): No action on metals or other
materials if material is kept dry (U.S. Army 1975, p. 3-10); otherwise, no
information found.
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits chloride and nitrogen oxides (Sax 1984, p. 2691).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION .VI - USE INFORMATION
Delayed-action casualty military agent (U.S. Army 1975, p. 3-10).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). (Non-Specific —
Poisonous Liquid, n.o.s.) Do not touch spilled material; stop leak if you
can do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Irritates the eyes in quantities which do
not significantly damage the skin or respiratory tract, insofar as single
exposures are concerned. After mild vapor exposure, there may be no skin
lesions. After severe vapor exposures, or after exposure to the liquid,
erythema may appear. Irritation and itching may occur. Later, blisters
-------
CAS Registry Number: 555-77-1
Page 4 of 4
TRIS(2-CHLOROETHYL)AMINE
SECTION IX (continued)
may appear in the erythematous areas. Effects on the respiratory tract
include irritation of the nose and throat, hoarseness progressing to loss
of voice, and a persistent cough. Fever, labored respiration, and moist
rales develop. Bronchial pneumonia may appear after the first 24 hours.
Following ingestion or systemic absorption, material causes inhibition of
cell mitosis, resulting in depression of the blood-forming mechanism and
injury to other tissues. Severe diarrhea, which may be hemorrhagic,
occurs. Lesions are most marked in the small intestine and consist of
degenerative changes and necrosis in the mucous membranes. Ingestion of 2
to 6 milligrams causes nausea and vomiting (U.S. Army 1975, p. 3-11).
Emergency and First Aid Procedures: (Non-Specific -- Nitrogen Mustards)
Stop exposure and treat symptomatically (Oilman 1985, p. 1257).
(Non-Specific -- Poisonous Liquid, n.o.s.) Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
NFPA 1984
Hawley 1981
Student 1981
-------
CAS Registry Number: 556-61-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY « METHYL ISOTHIOCYANATE
CAS Registry Number: 556-61-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 676) Methane,
Isothiocyanato-; Isothiocyanatomethane; Isothiocyanic Acid, Methyl Ester;
Methyl Mustard Oil; MIC; MIT; MITC; Morton EP-161E; Trapex; Trapexide; Vorlex;
Vortex; WN 12
Chemical Formula: C2H3NS
Molecular Weight: 73.12
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDEO dermal
(rabbit) 33 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 246°F, 119°C (Sax 1984, p. 1866)
Specific Gravity (H2O=1): 1.069 at 37°C/4°C (Weast 1983, p. C-376)
Vapor Pressure (mmHg): Not Found
Melting Point: 95-97°F, 35-36°C (Sax 1984, p. 1866)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Sax 1984, p. 1866)
Appearance and Odor: Crystalline (Sax 1984, p. 1866)
-------
CAS Registry Number: 556-61-6
Page 2 of 3
•
METHYL ISOTHIOCYANATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Farm Chemicals Handbook 1984,
p. C-242)
Skin: Yes (Farm Chemicals Handbook 1984, p. C-242)
Ingestion: Yes (NIOSH/RTECS 1983, p. 676)
Health Hazards (Acute, Delayed, and Chronic): Very toxic; probable human
oral lethal dose is 50-500 mg/kg, or between 1 teaspoonful and 1 oz. for a
70 kg (150 Ib.) person (Gosselin 1984, p. 11-352). Highly irritating to
skin, mucous membrances, and eyes (Sax 1984, p. 1866). Human oral minimum
lethal dose: approximately 1 g/kg (NIOSH/RTECS 1983, Volume 2, p. 676).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific ~ Pesticide, Solid,
n.o.s.) Move container from area if you can do so without risk. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Pesticide, Solid,
n.o.s.) This material may burn, but does not ignite readily. Fire may
produce irritating or poisonous gases (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Do not store below -20°C or at elevated
temperatures. Keep away from sparks (Farm Chemicals Handbook 1984, p.
C-242).
-------
CAS Registry Number: 556-61-6
Page 3 of 3
METHYL ISOTHIOCYANATE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated it emits very
dangerous cyanides and sulfur compounds (Sax 1984, p. 1866).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a soil fumigant. A mixture of methyl isothiocyanate and
chlorinated C3 hydrocarbons is used as a soil fumigant for control of
weeds, fungi, insects, and nematodes (Farm Chemicals Handbook 1984,
pp. C230, C242).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Extreme irritation of eyes, mucous
membranes, and skin. Coughing and other symptoms of extreme pulmonary
irritation would be expected if vapors are inhaled (Sax 1984, p. 1866).
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Remove and isolate contaminated clothing and
shoes at the site (DOT 1984, Guide 53).
-------
CAS Registry Number: 556-64-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHYL THIOCYANATE
CAS Registry Number: 556-64-9
Synonyms: Thiocyanic Acid, Methyl Ester; Thiocyanatomethane; Methyl
Rhodanate; Methyl Sulfocyanate
Chemical Formula: C2H3NS
Molecular Weight: 73.12
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDiow oral
(cat) 8.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 266-271°F, 130-133°C (Sax 1984, p. 1934)
Specific Gravity (H2O=1): 1.068 at 25°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 10.00 at 21.6°C (Perry, 1984, p. 3-58)
Melting Point: -60°F, -51°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very slight (*Merck 1976)
Appearance and Odor: Colorless liquid, onion odor (*Merck 1976)
-------
CAS Registry Number: 556-64-9
Page 2 of 4
METHYL THIOCYANATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic if ingested (Sax 1984, p. 1934). It is a rapidly acting poison
(*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash -Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Pesticide, Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specif ic -- Pesticide, Liquid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site.
If water pollution occurs, notify appropriate authorities (DOT 1984, Guide
55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984, p.
1934).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 556-64-9
Page 3 of 4
METHYL THIOCYANATE
SECTION V (continued)
Conditions to Avoid: This material is volatile (*Gosselin 1976)
Incompatibility (Materials to Avoid): (Non-Specific -- Thiocyanates)
Incompatible with nitric acid. Violent reactions have occurred when mixed
with chlorates, nitrates, nitric acid, organic peroxides, peroxides,
potassium chlorate, and sodium chlorate (Sax 1984, p. 2568).
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984, p.
1934).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as an agricultural insecticide, a fumigant (*Gosselin 1976), and
as a research chemical. No evidence of commercial production in the U.S.
(*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
(Non-Specific -- Pesticide, Liquid, n.o.s.) Do not touch spilled
material; stop leak if you can do so without risk. Use water spray
to reduce vapors. For small spills, absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. For large spills, dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Thiocyanates) Prolonged
absorption may produce various skin eruptions, runny nose, and
occasionally, dizziness, cramps, nausea, vomiting and mild or severe
disturbances of the nervous system (Sax 1984, p. 2568). (Non-Specific --
Aliphatic Thiocyanates) The ingestion of a concentrated solution may lead
to vomiting. The principal systemic reaction is probably one of central
-------
CAS Registry Number: 556-64-9
Page 4 of 4
*
METHYL THIOCYANATE
SECTION IX (continued)
nervous system depression, interrupted by periods of restlessness,
abnormally fast and deep respiratory movements and convulsions. Death is
usually due to respiratory arrest from paralysis of the medullary centers.
In nonfatal cases injuries to the liver and kidneys may appear (Gosselin
1981, p. IH-16).
Emergency and First Aid Procedures: (Non-Specific — Aliphatic
Thiocyanates) Because cyanide is probably largely responsible for
poisonings, antidotal measures against cyanide should be instituted
promptly (Gosselin 1981, p. Ill-16). (Non-Specific -- Cyanide Solution)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed, keep victim under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 558-25-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHANESULFONYL FLUORIDE
CAS Registry Number: 558-25-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 684) Fumette;
Methanesulphonyl Fluoride; MSF
Chemical Formula: CH3FO2S
Molecular Weight: 98.10
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(rat) 0.14 mg/liter (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 255°F, 124°C at 760 mmHg (Aldrich, 1986, p. 853)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 558-25-8
Page 2 of 3
METHANESULFONYL FLUORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1764)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Highly toxic when inhaled
(Sax 1984, p. 1764).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of fluorides and sulfur oxides (Sax 1984, p. 1764).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluorides and sulfur oxides (Sax 1984, p. 1764).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 558-25-8
Page 3 of 3
METHANESULFONYL FLUORIDE
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Weast 1979
DOT 1984
ACGIH 1984
NIOSH/OSHA 1978
Weiss 1980
Merck 1983
Buchel 1983
Encyc Occupat Health and Safety 1983
Farm Chemicals Handbook 1984
Hawley 1981
Clayton and Clayton 1981-82
Verschueren 1983
Student 1981
NFPA 1984
Gosselin 1984
-------
CAS Registry Number: 563-12-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHION
CAS Registry Number: 563-12-2
Synonyms: Phosphorodithioic Acid, S,S'-Methylene O,O,O',O'-Tetraethyl Ester;
AC 3422; Bis(S-(Diethoxyphosphinothioyl)Mercapto)Methane; Bladan; Diethion;
Embathion; ENT 24,105; Ethanox; Ethiol; Ethiol 100; Ethodan; Ethopaz; Ethyl
Methylene Phosphorodithioate; FMC-1240; Fosfatox E; Fosfono 50; Hylemax;
Hylemox; Itopaz; KWIT; NIA 1240; Niagara 1240; Nialate; O,O,O',O'- Tetraethyl
S,S'-Methylene Di(Phosphorodithioate); O,O,O',O'-Tetraethyl S,S'-
Methylenebisphosphordithioate; O,O,O',O'-Tetraethyl S,S'-Methylenebisphos-
phorodithioate; O,O,O,O-Tetraethyl S,S'-Methylenebis (Dithiophosphate);
Phosphorodithioic Acid, O,O-Diethyl Ester, S,S-Diester with Methanedithiol;
Phosphorodithioic Acid, S,S'-Methylene O,O,O',O'-Tetraethyl Ester;
Phosphotox E; Rhodiacide; Rhodocide; Rodocid; Rodocide; RP 8167; S,S'-Methylene
O,O,O',O'-Tetraethyl Phosphorodithioate; Soprathion; Tetraethyl S,S'-Methylene
Bis(Phosphorothiolothionate); Vegfru Fosmite
Chemical Formula: C9H22O4P2S4
Molecular Weight: 384.48
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 13 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.215-1.230 at 20°C/4°C (*Worthing 1979)
Vapor Pressure (mmHg): 0.0000015 at 77°F, 25°C (*Worthing 1979)
Melting Point: 9-10°F, -12 - -13°C (*Merck 1983)
-------
CAS Registry Number: 563-12-2
Page 2 of 4
•
ETHION
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (*Merck 1983)
Appearance and Odor: Colorless to amber-colored liquid (*Worthing 1979);
odorless (*Farm Chemicals Handbook 1984) or very disagreeable odor (*ACGIH
1980)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.4 mg/m3 (skin) (*ACGIH 1984)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is very
toxic; the probable oral lethal dose for humans is 50-500 mg/kg, which is
between one teaspoonful and one ounce for a 150-lb person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Does not ignite easily (*DOT 1984)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (*DOT
1984).
Special Fire Fighting Procedures: Move containers from fire area if it
can be done without risk. Dike fire control water for later disposal, do
not scatter the material. Fight fire from maximum distance. Wear positive
pressure breathing apparatus and protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Shock can shatter the container,
releasing the contents (*Sax 1979). Fire may produce irritating or
poisonous gases (*DOT 1984).
-!^
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 563-12-2
Page 3 of 4
ETHION
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Worthing 1979)
Stable:
Conditions to Avoid: Slowly oxidized in air (*Worthing 1979)
Incompatibility (Materials to Avoid): Hydrolyzed by acids and alkalies
(*Worthing 1979)
Hazardous Decomposition or Byproducts: Decomposes above 302°F, 150°C
(*Sunshine 1969). When heated to decomposition it emits highly toxic fumes
of oxides of sulfur and phosphorus (Sax 1984, p. 1372).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide and acaricide for citrus fruit, apples, nuts, other fruit, and
cotton (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Do not touch spilled
material. Use water spray to reduce vapors. Take up small spills
with sand or other noncombustible absorbent material. Large spills should
be diked far ahead of the spill for later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 563-12-2
Page 4 of 4
ETHION
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms may include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
weakness, muscle twitching, difficult breathing, blurring or dimness of
vision, and loss of muscle coordination. Death may occur from failure of
the respiratory center, paralysis of the respiratory muscles, intense
bronchoconstriction, or all three (*Gosselin 1976).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin and eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (*DOT 1984).
-------
CAS Registry Number: 563-41-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SEMICARBAZIDE HYDROCHLORIDE
CAS Registry Number: 563-41-7
Synonyms: Amidourea Hydrochloride; Aminourea Hydrochloride; Carbamylhydrazine
Hydrochloride; Hydrazinecarboxamide Monohydrochloride; Hydrazinecarboxamide,
.Hydrochloride; Hydrazinecarboxamide, Monohydrochloride; Semicarbazide Chloride;
Semicarbazide, Monohydrochloride
Chemical Formula: CH6N3OHC1
Molecular Weight: 111.54
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 342-347°F, 172-175°C (Hawley 1981, p. 914); decomposes at
347-365°F, 175-185°C (Merck 1983, p. 1214)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble in water with acid reaction (*Merck
1976)
-------
CAS Registry Number: 563-41-7
Page 2 of 3
SEMICARBAZIDE HYDROCHLORIDE
SECTION II (continued)
Appearance and Odor: Snow white crystals (*Hawley 1977)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Hawley 1981, p. 914)
Health Hazards (Acute, Delayed, and Chronic): Toxic by ingestion (Hawley
1981, p. 914).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Poisonous Solid, n.o.s.) This
material may burn, but does not ignite readily. For small fires use dry
chemical, carbon dioxide, water spray, or foam. For large fires, use water
spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Wear self-contained (positive pressure if available) breathing
apparatus and full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and hydrogen chloride (Sax 1984,
p. 2392).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 563-41-7
Page 3 of 3
SEMICARBAZIDE HYDROCHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found-
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of nitrogen oxides and hydrogen chloride (Sax 1984,
p. 2392).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
As a reagent for ketones and aldehydes with which it affords crystalline
compounds having characteristic melting points (Merck 1983, p. 1214).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Solid, n.o.s.) Isolate hazard area. Stay
upwind; keep out of low areas. Do not touch spilled material. Absorb
small spills with sand or other noncombustible absorbent material and
place into containers for later disposal. Take up small, dry spills
with clean shovel; place material into clean, dry container and cover;
move containers from spill area. Dike far ahead of large spills for
later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -*• Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at site. In case of contact with
material, immediately flush skin or eyes with running water for at least 15
minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 584-84-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TOLUENE 2,4-DIISOCYANATE
CAS Registry Number: 584-84-9
Synonyms: 2,4-Dicyanato-l-Methylphenylene; 2,4-Diisocyanato-l-Methyl-
benzene; 2,4-Diisocyanatotoluene; 2,4-TDI; 2,4-Toluene Diisocyanate;
2,4-Toluenediisocyanate; 2,4-Toluylene Diisocyanate; 2,4-Tolylene Diisocyanate;
2,4-Tolylenediisocyanate; 4-Methyl-m-Phenylene Diisocyanate;
4-Methyl-m-Phenylene Isocyanate; 4-Methyl-Phenylene Diisocyanate;
4-Methyl-Phenylene Isocyanate; Benzene, 2,4-Diisocyanato-l-Methyl; Desmodur
T80; Di-Iso-Cyanatoluene; Hylene T; Hylene TCP A; Hylene TLC; Hylene TM; Hylene
TM-65; Hylene TRF; Isocyanic Acid, 4-Methyl-m-Phenylene Ester; Isocyanic Acid,
Methylphenylene Ester; Meta-Toluene Diisocyanate; Mondur TD; Mondur TD-80;
Mondur TDS; Nacconate 100; NCI-C50533; Niax TDI; Niax TDI-P; Rubinate TDI
80/20; TDI; TDI-80; Toluene Diisocyanate; Toluene, 2,4-Diisocyanato-;
Toluene-2,4-Diisocyanate; Toluylene-2,4-Diisocyanate; Tolyene 2,4-Diisocyanate;
Tolyene-2,4-Diisocyanate; Tolylene Diisocyanate; Tolylene-2,4-Diisocyanate
Chemical Formula: C9H6N2O2
Molecular Weight: 174.15
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rabbit) 0.011 mg/liter/3 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 484°F, 251°C (*Merck 1983)
Specific Gravity (H2O=1): 1.2244 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at 80°C (*Clayton and Clayton 1981-82)
Melting Point: 67.1-70.7°F, 19.5-21.5°C (*Merck 1983)
-------
CAS Registry Number: 584-84-9
Page 2 of 4
TOLUENE 2,4-DIISOCYANATE
SECTION II (continued)
Vapor Density (AIR=1): 6.0 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Reacts with water evolving carbon dioxide (Merck
1983, p. 1364).
Appearance and Odor: Colorless, yellow or dark liquid or solid with a
sweet, fruity, pungent odor (NIOSH/OSHA 1978, p. 180).
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Ceiling 0.02 ppm (0.14 mg/ms) (NIOSH/OSHA 1978, p. 180)
ACGIH TLV: TWA 0.005 ppm (0.04 mg/ms); STEL 0.02 ppm (0.15 mg/ms) (*ACGIH
1984)
IDLH: 10 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: NIOSH: 0.035 mg/m3 10-hour TWA; 0.14 mg/ms
10-minute ceiling (NIOSH 1987, p. 226)
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 180)
Skin: Yes (NIOSH/OSHA 1978, p. 180)
Ingestion: Yes (NIOSH/OSHA 1978, p. 180)
Health Hazards (Acute, Delayed, and Chronic): Can cause death. Contact
with skin may cause allergic eczema. Substance is very corrosive to eyes.
Chronic exposure may cause chronic lung disease (*Gosselin 1976, Weiss
1980, p. 871, DASE 1980, p. 907). As a vapor TDI is a powerful irritant to
the respiratory tract. Chronic loss of respiratory function may occur
(*Gosselin 1976). Acute asthmatic bronchitis or frank asthma may occur
(*IARC 1972-85). A splash in the eyes of workmen has caused keratitis and
conjunctivitis (*Grant 1974). This compound causes inflammation of the
skin, also chemical pneumonitis and pulmonary edema (*ACGIH 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 270°F, 132°C (*Merck 1983)
Flammable Limits:
LEL: 0.9% (*NFPA 1978)
UEL: 9.5% (*NFPA 1978)
Extinguishing Methods: Water gently applied to surface or foam may cause
frothing which will extinguish the fire (*NFPA 1978). If material is on
fire or involved in fire do not extinguish fire unless flow can be stopped.
Use water in flooding quantities as fog. Solid streams of water may be
ineffective. Cool all affected containers with flooding quantities of
water. Apply water from as far a distance as possible. Use "alcohol"
-------
CAS Registry Number: 584-84-9
Page 3 of 4
TOLUENE 2,4-DIISOCYANATE
SECTION IV (continued)
foam, carbon dioxide or dry chemical. Use water spray to absorb vapor
(Student 1981, p. 503).
Special Fire Fighting Procedures: If water gets below the surface of the
liquid, it will turn to steam and cause frothing. Full protective
clothing, including self-contained breathing apparatus, rubber gloves,
boots and bands around legs, arms, and waist should be provided. No skin
surface should be exposed (*NFPA 1978). Move container from fire area if
you can do it without risk. Cool containers that are exposed to flames
with water from the side until well after fire is out. Dike fire control
water for later disposal; do not scatter the material (DOT 1984, Guide 57).
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
very toxic fumes of cyanide and nitrogen oxides (Sax 1984, p. 2590).
Reacts violently with amines, alcohol, bases and warm water causing fire
and explosion hazards (DASE 1980, p. 907).
NFPA Flammability Rating: 1
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 871)
Conditions to Avoid: Avoid heating (*NFPA 1978).
Incompatibility (Materials to Avoid): Strong oxidizers, water, acids,
bases, amines, etc., cause foam and splatter (NIOSH/OSHA 1978, p. 180)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of cyanide and nitrogen oxide (Sax 1984, p. 2590).
Hazardous Polymerization: May Occur: Yes (*Merck 1983)
May Not Occur:
Conditions to Avoid: Concentrated alkaline compound such as sodium
hydroxide or tertiary amines may cause run-away polymerization (*Merck
1983). Slow, not hazardous polymerization may occur above 113°C
(*CHRIS 1978).
SECTION VI - USE INFORMATION
Polyurethane foams; coatings in floor and wood finishes; sealers; paints;
concrete sealers for aircraft and tank trucks; elastomers in clay pipe
seals (*IARC 1972-1985); elastomers and coatings; and cross-linking agent
for nylon (Hawley 1981, p. 1030).
-------
CAS Registry Number: 584-84-9
Page 4 of 4
TOLUENE 2,4-DIISOCYANATE
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no smoking or flames in hazard area. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them (DOT 1984, Guide 57).
If material is not on fire and not involved in fire; keep sparks, flames,
and other sources of ignition away. Keep material out of water so.urces and
sewers. Build dikes to contain flow as necessary; attempt to stop leak if
without hazard. Use water spray to knock down vapors. If material is
leaking (not on fire), downwind evacuation must be considered (Student
1981, p. 503).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 584-84-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
TOLUENE 2,4-DIISOCYANATE
(584-84-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless to yellow liquid or solid below 19.5 degrees C (67.1
degrees F); darkens on exposure to sunlight.
Odor - Sharp, pungent.
Commercial Form - Colorless to light yellow liquid.
Uses - Chemical intermediate; cross-linking agent for nylon; manufacture of
polyurethane foams, sealers, paints, elastomers, and coatings.
Materials to Avoid - Water (except for use in emergency life support).
Caution: Mixing with water may result in a violent reaction. Sources of
extreme heat or ignition including sparks or fire may result in formation of
toxic nitrogen oxide gases.
Other Names - Desmodur T80; Hylene T; Mondur TD; Nacconate 100; Niax TDI;
2,4-TDI; TDI.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate.
Signs and Symptoms of Acute Toluene 2,4-Diisocyanate Exposure:
Signs and symptoms of acute exposure to toluene 2,4-diisocyanate may be severe
and include burning of the skin, eyes, nose, and throat. Cough, laryngitis,
chest pain, tightness of the chest, bronchitis, asthma, emphysema, and
enlargement of the right side of the heart may also occur. Gastrointestinal
effects may include vomiting, diarrhea, and abdominal pain. Headache,
insomnia, euphoria, depression, anxiety, paranoia, neuroses, and ataxia
(incoordination) may also be noted.
-------
EFATG
CAS Registry Number: 584-84-9
Page 2 of 3
TOLUENE 2,4-DIISOCYANATE
Emergency Life-Support Procedures:
Acute exposure to toluene 2,4-diisocyanate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to toluene 2,4-diisocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to toluene 2,4-diisocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 584-84-9
Page 3 of 3
TOLUENE 2,4-DIISOCYANATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. RUSH to a health care facility.
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CAS Registry Number: 594-42-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ PERCHLOROMETHYLMERCAPTAN
CAS Registry Number: 594-42-3
Synonyms: Trichloromethanesulfenyl Chloride; (Trichloromethyl)Sulfenyl
Chloride; Clairsit; Methanesulfenic Acid, Trichloro-, Chloride; Methanesulfenyl
Chloride, Trichloro-; PCM; Perchloro-Methyl-Mercaptan; Perchloromethanethiol;
Perchloromethyl Mercaptan; PMM; Thiocarbonyl Tetrachloride;
Trichloromethanesulphenyl Chloride; Trichloromethylsulfenyl Chloride;
Trichloromethylsulphenyl Chloride
Chemical Formula: CC14S
Molecular Weight: 185.87
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.296 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 297-298°F, 147-148°C (*Weast 1979)
Specific Gravity (H2O=1): 1.6947 at 20°C (*ACGIH 1980)
Vapor Pressure (mmHg): 25 at 51°C (Weast 1984, p. C-374)
Melting Point: Not Found
Vapor Density (AIR=1): 6.414 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*ACGIH 1980)
-------
CAS Registry Number: 594-42-3
Page 2 of 4
PERCHLOROMETHYLMERCAPTAN
SECTION II (continued)
Appearance and Odor: Oily, yellow (*ACGIH 1980) to orange-red liquid
(*CHRIS 1978). Odor is intensely unpleasant; strong, unbearable, acrid
("CHRIS 1978).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 ppm (0.8 mg/ms) (NIOSH 1987, p. 186)
ACGIH TLV: TWA 0.1 ppm (0.8 mg/ms) (*ACGIH 1980)
IDLH: 10 ppm (NIOSH/OSHA 1978, p. 150)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*CHRIS 1978)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): May cause death or
permanent injury after short exposure to small quantities (*Sax 1975);
strong irritant to eyes and skin (*Hawley 1977). Inhalation may cause
severe irritation of the upper respiratory tract. It also is a strong
irritant to the eyes and skin. Brief exposure to lower concentrations may
produce central nervous system depression and lung, liver, and heart
congestion. Severe exposures may be fatal. Exposure of eyes may lead to
severe conjunctivitis or corneal damage. The liquid is irritating to the
skin, and may be absorbed through the skin in quantities sufficient to
cause general toxic effects. Ingestion may cause damage to mucous
membranes and result in pain and burning of the mouth and throat, nausea,
vomiting, cramps, and diarrhea. In severe cases, tissue ulceration and CNS
depression may occur (*CHRIS 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is neither flammable nor a serious
fire hazard, although it will support combustion (*ACGIH 1980). Fight
small fires with dry chemical, carbon dioxide, water spray, or foam, and
large fires with water spray, fog, or foam. Move containers containing
this compound away from fire area if possible (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material.
Positive pressure breathing apparatus and special protective clothing
should be worn (DOT 1984, Guide 55).
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CAS Registry Number: 594-42-3
Page 3 of 4
PERCHLOROMETHYLMERCAPTAN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Very irritating vapors formed from
hot material; may form phosgene gas, hydrogen chloride, and sulfur dioxide
(Weiss 1980, p. 739).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 739)
Conditions to Avoid: Reacts with water only when hot to give carbon
dioxide, hydrochloric acid, and sulfur (Weiss 1980, p. 739).
Incompatibility (Materials to Avoid): Reacts with iron or steel, evolving
carbon tetrachloride. Corrosive to most metals (Weiss 1980, p. 739).
Hazardous Decomposition or Byproducts: At high temperatures this compound
will decompose to carbon tetrachloride, sulfur chloride, heavy oil
polymers, phosgene gas, hydrogen chloride, and sulfur dioxide (Weiss 1980,
p. 739).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 739)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This compound is used as a f umigant, dye intermediate, and in other organic
syntheses (*ACGIH 1980).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if this can be done without risk.
Use water spray to reduce vapors. Take up small spills with sand or other
noncombustible absorbent material and place into containers for later
disposal. For large spills dike far ahead of spill for later disposal.
It may be necessary to seek emergency assistance (DOT 1984, Guide 55).
SECTION VIII « PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 594-42-3
Page 4 of 4
PERCHLOROMETHYLMERCAPT AN
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 594-42-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
PERCHLOROMETHYLMERCAPTAN
(594-42-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Oily, yellow to orange-red liquid.
Odor - Intensely unpleasant.
Commercial Form - 97% pure liquid.
Uses - Fumigant, manufacture of dyes and pesticides.
Materials to Avoid - Iron, steel, water (except for use in emergency life
support).
Caution: Avoid sources of heat including fire. Perchloromethylmercaptan wi
liberate carbon tetrachloride, phosgene, and hydrogen chloride fumes when
heated to decomposition.
Other Names - Clairsit, perchloromethanethiol, trichloromethanesulfenyl
chloride, thiocarbonyl tetrachloride, trichloromethyl sulfur chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Perchloromethylmercaptan Exposure:
Signs and symptoms of acute exposure to Perchloromethylmercaptan may lead to
liver, heart, and kidney damage. Respiratory effects include coughing, dyspnea
(shortness of breath), painful breathing, and lung congestion. Tachycardia
(rapid heart rate) is often observed. Nausea, vomiting, abdominal cramping,
and diarrhea may also occur. Contact with Perchloromethylmercaptan may result
in severe dermatitis (red, inflamed skin), conjunctivitis (red, inflamed eyes),
and burns with ulceration and severe pain.
-------
EFATG
CAS Registry Number: 594-42-3
Page 2 of 3
PERCHLOROMETHYLMERCAPTAN
Emergency Life-Support Procedures:
Acute exposure to perchloromethylmercaptan may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to perchloromethylmercaptan.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to perchloromethylmercaptan.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 594-42-3
Page 3 of 3
PERCHLOROMETHYLMERCAPTAN
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. Transport to a health care facility.
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CAS Registry Number: 597-64-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TETRAETHYLTIN
CAS Registry Number: 597-64-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 634) Stannane,
Tetraethyl-; Tetraethylstannane; Tin, Tetraethyl; TET
Chemical Formula: C8H20Sn
Molecular Weight: 234.97
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rabbit) 7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 358°F, 181°C (Weast 1979, p. C-717)
Specific Gravity (H2O=1): 1.187 at 23°C (Weast 1979, p. C-717)
Vapor Pressure (mmHg): Not Found
Melting Point: -170°F, -112°C (Weast 1979, p. C-717)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. C-717)
Appearance and Odor: Colorless liquid (Weast 1979, p. C-717).
-------
CAS Registry Number: 597-64-8
Page 2 of 4
•
TETRAETHYLTIN
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: (Tin, organic compounds) TWA: 0.1 mg/ms, as tin (NIOSH 1987,
p. 224)
ACGIH TLV: (Tin, organic compounds) 0.1 mg/m3, as tin (skin)
(ACGIH, 1986-87, p. 31)
IDLH: Not Found
Other Limits Recommended: (Non-Specific — Organic Tin Compounds) NIOSH
recommended standard: Air: TWA 0.1 mg (tin)/ms; IDLH for tin compounds,
organic, 200 mg/m3 (NIOSH/OSHA 1978, p. 180).
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 2527)
Ingestion: Yes (Sax 1984, p. 2527)
Health Hazards (Acute, Delayed, and Chronic): Toxic hazard rating is high
for oral, intravenous, intraperitoneal administration (Sax 1984, p. 2527).
This material causes swelling of the brain and spinal cord (Hayes 1982, p.
37).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is a liquid organotin pesticide (Hayes 1982,
p. 37). This material may burn but does not ignite readily. Extinguish
small fires with dry chemical, carbon dioxide, water spray or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This is a liquid organotin pesticide
(Hayes 1982, p. 37). Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2527).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 597-64-8
Page 3 of 4
TETRAETHYLTIN
SECTION V (continued)
Incompatibility (Materials to Avoid): (Non-Specific -- Organic Tin
Compounds) Strong oxidizers (NIOSH/OSHA 1978, p. 180)
Hazardous Decomposition or Byproducts: Acrid smoke and fumes are emitted
upon decomposition by heat (Sax 1984, p. 2527).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
(Non-Specific — Organotin Compounds) Used as biocides, bactericides,
fungicides and insecticides; preservatives for wood, textile, paper, and
leather (Clayton and Clayton 1981-82, p. 1953). Not registered as a
pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is a liquid organotin pesticide (Hayes 1982, p. 37). Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Tetrasubstituted Tin
Compound) Exposure may result in muscular weakness and paralysis, leading
to respiratory failure; convulsive movements; closure of eyelids and
sensitivity to light (Clayton and Clayton 1981-82, p. 1955); headaches, and
EEG changes (Doull 1980, p. 458); dizziness, psychological and neurological
disturbances, sore throat, cough, abdominal pain, nausea, and vomiting
(NIOSH/OSHA 1978, p. 181).
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CAS Registry Number: 597-64-8
Page 4 of 4
TETRAETHYLTIN
SECTION IX (continued)
Emergency and First Aid Procedures: This is a liquid organotin pesticide
(Hayes 1982, p. 37). Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least IS minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 614-78-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 13, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THIOUREA, (2-METHYLPHENYL)-
CAS Registry Number: 614-78-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 890) Urea,
2-Thio-l-o-Tolyl-; o-Tolyl Thiourea; l-o-Tolyl-2-Thiourea
Chemical Formula: C8H10N2S
Molecular Weight: 166.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 304-306°F, 151-152°C (Sax 1984, p. 2601); 324°F, 162°C
(Weast 1984, p. C-539)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (Weast 1979, p. C-540)
Appearance and Odor: Crystalline solid (Sax 1984, p. 2601)
-------
CAS Registry Number: 614-78-8
Page 2 of 4
THIOUREA, (2-METHYLPHENYL)-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2601)
Health Hazards (Acute, Delayed, and Chronic): The material is highly
toxic if orally ingested (Sax 1984, p. 2601).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous Solid, n.o.s.) For
small fires use dry chemical, carbon dioxide, water spray, or foam. Use
water spray, fog, or foam on larger fires. Move container from fire area
if you can do so without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Wear self-contained (positive pressure if available) breathing
apparatus and full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984,
p. 2601).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen and sulfur (Sax 1984,
p. 2601).
-------
CAS Registry Number: 614-78-8
Page 3 of 4
THIOUREA, (2-METHYLPHENYL)-
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Solid, n.o.s.) Keep unnecessary people away,
isolate hazard area and deny entry. Stay upwind and keep out of low areas.
Do not touch spilled material, stop leak if you can do so without risk.
Absorb small spills with sand or other noncombustible material and place
into containers for later disposal. For large spills, dike far ahead of
spill for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Move victim to fresh air and call emergency medical care. Remove
and isolate contaminated clothing and shoes at the site. In case of
contact with the material, immediately flush skin or eyes with running
water for at least 15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
-------
CAS Registry Number: 614-78-8
Page 4 of 4
THIOUREA, (2-METHYLPHENYL)-
COMMENTS (continued)
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Oilman 1985
Verschueren 1983
-------
CAS Registry Number: 624-83-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHYL ISOCYANATE
CAS Registry Number: 624-83-9
Synonyms: Isocyanic Acid, Methyl Ester; MIC; Iso-Cyanatomethane;
Isocyanatomethane; Methane, Isocyanato-
Chemical Formula: C2H3NO
Molecular Weight: 57.05
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.012 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory)
Section 313 Listed (Yes or No): Yes
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 102°F, 39°C (NIOSH/OSHA 1978, p. 130)
Specific Gravity (H2O=1): 0.9599 at 20°C/20°C (*Sax 1979)
Vapor Pressure (mmHg): 348 at 20°C (*ACGIH 1980)
Melting Point: -112°F, -80°C (NIOSH/OSHA 1978, p. 130)
Vapor Density (AIR=1): About twice as heavy as air (Worthy 1985, p. 27)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 6.7 g/100 mL (NIOSH/OSHA 1978, p. 130)
Appearance and Odor: Colorless liquid (*Hawley 1981); sharp odor
(NIOSH/OSHA 1978, p. 130)
-------
CAS Registry Number: 624-83-9
Page 2 of 4
METHYL ISOCYANATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA: 0.02 ppm (0.05 mg/m3) (NIOSH/OSHA 1978, p. 130)
ACGIH TLV: TWA: 0.02 ppm (0.05 mg/ms) (skin) (ACGIH 1983, p. 26)
IDLH: 20 ppm (NIOSH/OSHA 1978, p. 130)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*NIOSH/RTECS 1985)
Skin: Yes (Sax 1984, p. 1864)
Ingestion: Yes (Dagani 1985, p. 37)
Health Hazards (Acute, Delayed, and Chronic): This compound is a skin
irritant and can cause permanent eye damage (*ACGIH 1980). A concentration
of 2 ppm has been reported toxic in humans (*NIOSH/RTECS 1985). Methyl
isocyanate attacks the respiratory system, eyes and skin. It can injure
the lungs and bronchial airways, cause permanent eye damage, and death.
Death has been attributed to various forms of respiratory distress (Dagani
1985, p. 38).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 19°F, -7°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 5.3 percent (*NFPA 1978)
UEL: 26 percent (*NFPA 1978)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide
30).
Special Fire Fighting Procedures: Material is extremely hazardous to
health but areas may be entered with extreme care. Full protective
clothing, including self-contained breathing apparatus (coat, pants,
gloves, boots, and bands around legs, arms and waist) should be provided.
No skin surface should be exposed (*NFPA 1978). Stay away from ends of
tanks. Do not get water inside container. Spray cooling water on
containers that are exposed to flames until well after fire is out.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire (DOT 1984, Guide 30).
Unusual Fire and Explosion Hazards: Reacts violently with water (*NFPA
1978). Extremely flammable; may be ignited by heat, sparks, or flames.
Vapors may travel to a source of ignition and flash back. Container may
explode violently in heat of fire. Vapor explosion and poison hazard
indoors, outdoors, or in sewers. Runoff to sewer may create fire or
explosion hazard (DOT 1984, Guide 30).
NFPA Flammability Rating: 3
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CAS Registry Number: 624-83-9
Page 3 of 4
METHYL ISOCYANATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Avoid heat, flame, oxidizers, water (*Sax 1979).
Incompatibility (Materials to Avoid): Water, acids, alkali, amines, iron,
tin, copper, and other catalysts (*Sittig 1981).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
. emits toxic fumes of nitrogen oxides (Sax 1984, pp. 1863-4).
Hazardous Polymerization: May Occur: Yes (Worthy 1985, p. 28)
May Not Occur:
Conditions to Avoid: Methyl isocyanate (MIC) will react with water,
or in the presence of catalysts (such as sodium hydroxide, sodium
methoxide, triphenylarsine, triethyl phosphine, metallic chlorides) to
form either a cyclic trimer (trimethyl isocyanurate) or a gummy,
resinous polymer. These reactions are exothermic, producing about 540
Btu per pound of MIC. Heat produced in these reactions may result in
pressure build up and rupturing of tanks (Worthy 1985, p. 28).
SECTION VI - USE INFORMATION
Methyl isocyanate is used as an intermediate in the manufacturing of
N-methylcarbamate ester and N-methylurea insecticides and herbicides, such
as the carbaryl insecticide Sevin, the aldicarb insecticide Termik,
additional insecticides carbofuran, methomyl, bendiocarb, and oxamyl, and
the herbicides methazole and tebuthiuron (Chem. & Eng. News, December 10,
1984, p. 7).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Shut off ignition sources; no flares,
smoking or flames in hazard area. Do not touch spilled material; stop leak
if you can do so without risk. Use water spray to reduce vapors, do not
get water inside container. Small spills: flush area with flooding
amounts of water. Large spills: dike far ahead of spill for later
. disposal (DOT 1984, Guide 30). For small quantities, absorb on paper
towels. Evaporate in safe place such as a fume hood. Allow sufficient
time for vapors to completely clear the hood ductwork. Burn the paper in a
suitable location away from combustible materials. Reclaim and atomize
large quantities in a combustion chamber with an effluent gas cleaning
device. Do not allow this gas to enter a confined space such as a sewer
because of the possibility of an explosion (*NIOSH/OSHA 1981).
-------
CAS Registry Number: 624-83-9
Page 4 of 4
METHYL ISOCYANATE
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Neoprene POOR/MANY
Viton POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 624-83-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHYL ISOCYANATE
(624-83-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, pungent.
Use - Manufacture of pesticides.
Materials to Avoid - Acids, alkali, metals, water (except for use in emergency
life support).
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. Methyl isocyanate may polymerize violently in the
presence of water.
Other Names - Isocyanatomethane; isocyanic acid, methyl ester; MIC.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, atropine,
homatropine.
Signs and Symptoms of Acute Methyl Isocyanate Exposure:
Warning: Effects may be delayed for up to 15 hours. Caution is advised.
Acute exposure to methyl isocyanate may result in respiratory tract irritation,
cough, chest tightness and pain, dyspnea (shortness of breath), asthmatic
episodes, and pulmonary edema. Contact with the skin, eyes, and mucous
membranes may result in severe irritation and permanent damage.
-------
EFATG
CAS Registry Number: 624-83-9
Page 2 of 3
METHYL ISOCYANATE
Emergency Life-Support Procedures:
Acute exposure to methyl isocyanate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methyl isocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methyl isocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 624-83-9
Page 3 of 3
METHYL ISOCYANATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
4. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
5. Transport to a health care facility.
-------
CAS Registry Number: 624-92-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHYL BISULFIDE
CAS Registry Number: 624-92-0
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 173): Disulfide,
Dimethyl; Dimethyldisulfide
Chemical Formula: C2H6S2
Molecular Weight: 94.20
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.0123 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 229.5°F, 109.7°C (Sax 1984, p. 1156)
Specific Gravity (H2O=1): 1.0569 at 25°C (Sax 1984, p. 1156)
Vapor Pressure (mmHg): 28.6 at 25°C (Sax 1984, p. 1156)
Melting Point: -120.5°F, -84.72°C (Clayton and Clayton 1981-82,
p. 2064)
Vapor Density (AIR=1): 3.24 (Sax 1984, p. 1156)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Clayton and Clayton 1981-82, p. 2062)
Appearance and Odor: Liquid (Sax 1984, p. 1156); odor detection limit is
0.33 to 1.2 ppb in water (Clayton and Clayton 1981-82, p. 2087)
-------
CAS Registry Number: 624-92-0
Page 2 of 4
METHYL BISULFIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 19S4, p. 1156)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This is highly toxic by
inhalation. Health hazards resemble those of sulfides and alkyl disulfides
(Sax 1984, p. 1156).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 44.6°F (Sax 1984, p. 1156)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Dimethylsulfide) Small fires:
dry chemical, carbon dioxide, water spray, or foam. Large fires: water
spray, fog, or foam. Move container from fire area if you can do so
without risk. Spray cooling water on containers that are exposed to flames
until well after fire is out. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (DOT 1984,
Guide 57).
Special Fire Fighting Procedures: (Non-Specific — Dimethylsulfide) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Wear
positive pressure breathing apparatus and special protective clothing (DOT
1984, Guide 57).
Unusual Fire and Explosion Hazards: (Non-Specific — Dimethylsulfide)
May be ignited by heat, sparks or flames. Container may explode in heat of
fire. Vapor explosion and poison hazard indoors, outdoors or in sewers
(DOT 1984, Guide 57).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 624-92-0
Page 3 of 4
METHYL DISULFIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Oxidizing materials (Sax 1984, p.
1156)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of sulfur oxide (Sax 1984, p. 2482). Photo-
chemically, it is oxidized by ozone (Clayton and Clayton 1981-82,
p. 2087).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapor (see Section III above). (Non-Specific --
Dimethylsulfide) Shut off ignition sources; no flares, smoking, or flames
in hazard area. Do not touch spilled material; stop leak if you can do so
without risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill
for later disposal (DOT 1984, Guide 57).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Dimethylsulfides)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
-------
CAS Registry Number: 624-92-0
Page 4 of 4
METHYL DISULFIDE
SECTION IX (continued)
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed, keep victim under observation (DOT 1984, Guide 57).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 625-55-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ISOPROPYL FORMATE
CAS Registry Number: 625-55-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 339) Formic Acid,
Isopropyl Ester; NCI-C60106
Chemical Formula: C^gOj
Molecular Weight: 88.12
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 1.4 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 154.8°F, 68.2°C (Weast 1979, p. C-310)
Specific Gravity (H2O=1): 0.8728 (Weast 1979, p. C-310)
Vapor Pressure (mmHg): 100 at 17.8°C (Sax 1984, p. 1659)
Melting Point: Not Found
Vapor Density (AIR=1): 3.03 (Sax 1984, p. 1659)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Clayton and Clayton 1981-82,
p. 2264)
Appearance and Odor: Clear liquid, pleasant odor (Clayton and Clayton
1981-82, p. 2264)
-------
CAS Registry Number: 625-55-8
Page 2 of 4
ISOPROPYL FORMATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Clayton and Clayton 1981-82,
p. 2264)
Skin: Yes (Clayton and Clayton 1981-82, p. 2264)
Ingestion: Yes (Sax 1984, p. 1659)
Health Hazards (Acute, Delayed, and Chronic): Vapor produces eye and nose
irritation, while the liquid produces eye and skin irritation (Clayton and
Clayton 1981-82, p. 2265).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 22°F, -5.6°C (CC) (Clayton and Clayton
1981-82, p. 2264)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam. Move container
from fire area if you can do it without risk. Cool containers that are
exposed to flames with water from the side until well after fire is out.
For massive fire in cargo area, use unmanned hose holder or monitor
nozzles; if this is impossible, withdraw from area and let fire burn.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire (DOT 1984, Guide 27).
Special Fire Fighting Procedures: Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing. Isolate
for 1/2 mile in all directions if tank car or truck is involved in fire
(DOT 1984, Guide 27).
Unusual Fire and Explosion Hazards: Vapors may travel to a source of
ignition and flash back. Container may explode in heat of fire. Vapor
explosion hazard indoors, outdoors or in sewers. Runoff to sewer may
create fire or explosion hazard (DOT 1984, Guide 27).
NFPA Flammability Rating: 3
-------
CAS Registry Number: 625-55-8
Page 3 of 4
ISOPROPYL FORMATE
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Reacts vigorously with oxidizing
materials (Sax 1984, p. 1659).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Formic acid, isopropyl ester, is used as a fumigant and as a synthetic raw
material (Clayton and Clayton 1981-82, p. 2265).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Shut off ignition sources; no flares,
smoking or flames in hazard area. Stop leak if you can do so without risk.
Use water spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 27).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
-------
CAS Registry Number: 625-55-8
Page 4 of 4
ISOPROPYL FORMATE
SECTION VIII (continued)
Viton POOR/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Ethyl Formate)
Inhalation of vapor can cause irritation of eyes and nose. High
concentrations can cause unconsciousness in a few minutes, with death
within a few hours. Contact with liquid formic acid, isopropyl ester can
cause irritation of eyes and skin. Ingestion can result in irritation of
the mouth and stomach, with loss of consciousness and death occurring if
untreated (Clayton and Clayton 1981-82, p. 2265; Weiss 1980, p. 446).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush eyes with running water for at least 15 minutes. Wash
skin with soap and water. Remove and isolate contaminated clothing and
shoes at the site (DOT 1984, Guide 27)
-------
CAS Registry Number: 627-11-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLOROETHYL CHLOROFORMATE
CAS Registry Number: 627-11-2
Synonyms: (SANSS 1983 Synonyms) Formic acid, Chloro-, 2-Chloroethyl Ester;
Carbonochloridic Acid, 2-Chloroethyl Ester; .beta.-Chloroethyl Chloroformate;
(2-Chloroethoxy)carbonyl Chloride; Chloroformic Acid, 2-Chloroethyl Ester; TL
207; 2-Chloroethyl Chlorocarbonate; 2-Chloroethyl Chloroformate
Chemical Formula: C3H4C12O2
Molecular Weight: 142.97
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCiow inhalation
(mouse) 0.2 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 312.3°F, 155.7°C (Weast 1978, p. C-310)
Specific Gravity (H2O=1): 1.3847 (Weast 1978, p. C-310)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1978, p. C-310)
Appearance and Odor: Not Found
-------
CAS Registry Number: 627-11-2
Page 2 of 4
*
CHLOROETHYL CHLOROFORMATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Ethyl
Chloroformate) Poisonous; may be fatal if inhaled, swallowed or absorbed
through skin. Contact may cause burns to skin and eyes (DOT 1984, Guide
28).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 627-11-2
Page 3 of 4
CHLOROETHYL CHLOROFORMATE
SECTION VI « USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Ethyl Chloroformate) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire. Shut off ignition sources; no flares, smoking or flames in hazard
area. Do not touch spilled material; stop leak if you can do so without
. risk. Use water spray to reduce vapors. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 28).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene GOOD/LIMITED**
Nitrile POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Ethyl Chloroformate)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Remove and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 28).
-------
CAS Registry Number: 627-11-2
Page 4 of 4
CHLOROETHYL CHLOROFORMATE
COMMENTS
Sources searched but no information found:
Hawley 1981
Hayes 1982
Merck 1983
Clayton and Clayton 1981-82
CHRIS 1978
Weiss 1980
NFPA 1978
DASE 1980
Encyc Occupat Health and Safety 1983
Hayes 1982
Buchel 1983
-------
CAS Registry Number: 630-60-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- OUABAIN
CAS Registry Number: 630-60-4
Synonyms: 3-((6-Deoxy-alpha-L-Mannopyranosyl)Oxy)-1,5,11 alpha, 14,19-
Pentahydroxycard-20(22)-Enolide; Acocantherin; Astrobain; Card-20(22)-Enolide,
3-((6-Deoxy-alpha-L-Mannopyranosyl)Oxy)-l,5,ll,14,19-Pentahydroxy-,
(lbeta,3beta,5beta, 11 alpha)-; G-Strophanthin; G-Strophicor; Gratibain; Gratus
Strophanthin; Kombetin; Ouabagenin L-Rhamnoside; Ouabaine; Purostrophan;
Rectobaina; Solufantina; Strodival; Strophalen; Strophanthin G; Strophanthin
Thorns; Strbphoperm; Strophosan
Chemical Formula: C2gH44O12
Molecular Weight: 584.64
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 8.28 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 392°F, 200°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g/ 75 mL (Merck 1983, p. 990).
-------
CAS Registry Number: 630-60-4
Page 2 of 4
OUABAIN
SECTION II (continued)
Appearance and Odor: Odorless, white crystals or crystalline powder as an
octahydrate (*Osol 1980).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely toxic. Probable oral lethal dose in humans is less than 5 mg/kg
or a taste (less than 7 drops) for 70 kg (150-lb.) person (*Gosselin 1976).
Exposure may result in respiratory and cardiac failure, and/or
hyperalkemia (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Patients with
frequent premature ventricular heart beats or who have received any
preparation of digitalis during preceding three weeks are prone to toxicity
(*Gilman 1980).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Medicine, n.o.s.) For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 11).
Special Fire Fighting Procedures: (Non-Specific — Medicine, n.o.s.)
Cool containers that are exposed to flames with water from the side until
well after fire is out. For massive fires use unmanned hose holder or
monitor nozzles; if this is impossible, withdraw and let fire burn. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing (DOT 1984, Guide 11).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2097).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 630-60-4
Page 3 of 4
OUABAIN
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Stable in air, but affected by light (ouabain
octahydrate) (*Osol 1980)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Hydrolysis yields one mole
ouabagenin and one mole rhamnose (Merck 1983, p. 990). When heated to
decomposition, it emits acrid smoke and fumes (Sax 1984, p. 2097).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Indicated to produce rapid digitalization in acute congestive heart
failure. Also recommended in treatment of atrial or nodal paroxysmal
tachycardia and atrial flutter (Physicians' Desk Reference 1980, p. 1069).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Medcines, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low
areas. If water pollution occurs, notify appropriate authorities.
Shut off ignition sources; no flares, smoking or flames in hazard area.
Keep combustibles (wood, paper, oil, etc.) away from spilled material.
Do not touch spilled material. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material
into clean, dry container and cover; move container from spill area.
Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 11).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 630-60-4
Page 4 of 4
*
OUABAIN
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of heart failure occur, with
marked increase in serum potassium. Signs may include confusion, vomiting,
coma, convulsions, and respiratory failure (*Rumack 1975 to Present; Oilman
1985, p. 738).
Emergency and First Aid Procedures: (Non-Specific -- Medicine, n.o.s.)
Move victim to fresh air, call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In
case of contact with material, immediately flush skin or eyes with running
water for at least 15 minutes. Remove and isolate contaminated clothing
and shoes at the site. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 11).
-------
CAS Registry Number: 639-58-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY « TRIPHENYLTIN CHLORIDE
CAS Registry Number: 639-58-7
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, page 627): Stannane,
Chlorotriphenyl-; Brestanol; Chlorotriphenylstannane; Chlorotriphenyltin;
Fentin Chloride; GC 8993; General Chemicals 8993; HOE 2872; LS 4442; TPTC;
Tinmate; Triphenylchlorostannane; Triphenylchlorotin
Chemical Formula: C18H15ClSn
Molecular Weight: 385.47
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 18 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 464°F, 240°C at 13.5 mmHg (Sax 1984, p. 782)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 223°F, 106°C (Sax 1984, p. 782)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Sax 1984, p. 782) 40 ppm (Farm Chemicals
Handbook 1984, p. C-234)
Appearance and Odor: White crystalline solid (Hawley 1977, p. 1057)
-------
CAS Registry Number: 639-58-7
Page 2 of 4
TRIPHENYLTIN CHLORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Tin, organic compounds) TWA 0.1 mg/ms, as tin, (NIOSH 1987,
• p. 224)
ACGIH TLV: (Tin, organic compounds) TWA 0.1 mg/ms, as tin (skin) (ACGIH,
1986-87, p. 31)
IDLH: Not Found
Other Limits Recommended: (Non-Specific -- Tin Compounds, Organic) IDLH
200 mg/ms (NIOSH/OSHA 1978, p. 180). Occupational exposure to organotin
compounds recommended standard -- Air: TWA 0.1 mg (Sn)/ms (NIOSH/RTECS
1983, Volume 3, p. 627).
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 2582)
Ingestion: Yes (Sax 1984, p. 782)
Health Hazards (Acute, Delayed, and Chronic): -Toxic and irritating to the
skin (Hawley 1977, p. 1057). Dermal exposure may lead to severe skin burns
as well as renal failure and possible death (Clayton and Clayton 1981-82,
p. 1965). (Non-Specific -- Tin Compounds, Organic) Target organs affected
are central nervous system, eyes, liver, urinary tract, skin and the blood
(NIOSH/OSHA 1978, p. 181).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Pesticide, Solid, n.o.s.)
Extinguish fires with dry chemical, carbon dioxide, water spray, fog, or
foam. Move container from fire area if you can do so without risk. Fight
fire from maximum distance. Dike fire control water for later disposal; do
not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated, it emits toxic fumes of
chlorides (Sax 1984, p. 782).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 639-58-7
Page 3 of 4
TRIPHENYLTIN CHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, when stored in dark with dry air (Farm
Chemicals Handbook 1984, p. C234)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzes to hydroxide in water
(Farm Chemicals Handbook 1984, p. C234)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides (Sax 1984, p. 782).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a rodent repellent, molluscicide, fungicide and insecticide
(Clayton and Clayton 1981-82, p. 1952).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Organic Tin Compounds)
Eye irritation and acute local skin burns, irritation of the respiratory
tract on inhalation and irritation of the gastrointestinal tract following
-------
CAS Registry Number: 639-58-7
Page 4 of 4
TRIPHENYLTIN CHLORIDE
SECTION IX (continued)
ingestion (Encyc Occupat Safety and Health 1983, p. 2179). (Non-Specific
— Tin Compounds, Organic) Other symptoms include headache, dizziness,
sore throat, cough, abdominal pain, vomiting, urine retention and skin
burns (NIOSH/OSHA 1978, p. 181).
Emergency and First Aid Procedures: In case of a dermal exposure, wash
with water or scrub with a strong detergent soap and water (Clayton and
Clayton 1981-82, p. 1966). In case of ingestion, induce vomiting and treat
symptomatically (Farm Chemicals Handbook 1984, p. 234).
COMMENTS
Sources searched but no information found:
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Arena 1979
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
Weast 1979
-------
CAS Registry Number: 640-19-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FLUOROACETAMIDE
CAS Registry Number: 640-19-7
Synonyms: 2-Fluoroacetamide; 1081; Acetamide, 2-Fluoro-; AFL 1081; Compound
1081; FAA; Fluorakil 100; Fluoroacetic Acid Amide; Fussol; Megatox;
Monofluoroacetamide; Navron; Rodex; Yanock
Chemical Formula: C2H4FNO
Molecular Weight: 77.06
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(rat) 5.75 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Sublimes on heating (Hayes 1982, p. 499)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 225-228°F, 107-109°C (Hayes 1982, p. 499)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (*Merck 1976)
Appearance and Odor: Colorless crystalline powder (*Worthing 1979)
-------
CAS Registry Number: 640-19-7
Page 2 of 3
•
FLUOROACETAMIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Hayes 1982)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is super
toxic; probable oral lethal dose in humans is less than 5 mg/kg, or a taste
(less than 7 drops) for a 150-lb. person (*Gosselin 1976). Chemically
inhibits oxygen metabolism by cells with critical damage occurring to the
heart, brain, and lungs resulting in heart failure, respiratory arrest,
convulsions, and death (Oilman 1980, p. 1644).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1428)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits very toxic fumes of fluorine
containing compounds and nitrogen oxides when heated to decomposition (Sax
1984, p. 1428).
-------
CAS Registry Number: 640-19-7
Page 3 of 3
FLUOROACETAMIDE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Rodenticide (*SRI); insecticide proposed mainly for use on fruits to combat
scale insects, aphids, and mites (*Merck 1976). Use is largely restricted
to licensed pest control operators (*Doull 1980).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Sodium Fluoroacetate) Do not touch spilled material; stop
leak if you can do so without risk. Small spills: absorb with sand or
other non-combustible absorbent material and place into containers for
later disposal. Large spills: dike spill for later disposal. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
POOR/LIMITED**
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
Viton POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 640-19-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
FLUOROACETAMIDE
(640-19-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Fluoroacetamide is extremely toxic. There is no known antidote*
Immediately transport victims to a health care facility.
Substance Characteristics:
Pure Form - Colorless crystals.
Commercial Form - Powder.
Use - Pesticide.
Caution: Highly toxic fumes of fluorine-containing compounds and nitrogen
oxides will be emitted when fluoroacetamide is heated to decomposition. Avoid
sources of extreme heat including fire.
Other Names - Baran, FAA, fluoroacetic acid amide, Fussol, Megatox,
monofluoroacetamide, Navron, Rodex, Yanock.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin.
Signs and Symptoms of Acute Fluoroacetamide Exposure:
Warning: Effects usually appear within 30 minutes of exposure but may be
delayed as long as 20 hours. Caution is advised. Vital signs should be
monitored closely.
Signs and symptoms may be extremely severe and range from nausea, vomiting,
and diarrhea to convulsions, coma, and heart failure. Other symptoms include
hyperactivity, respiratory depression or arrest, cyanosis (blue tint to the
skin and mucous membranes), and ventricular fibrillation.
-------
EFATG
CAS Registry Number: 640-19-7
Page 2 of 3
FLUOROACETAMIDE
Emergency Life-Support Procedures:
Acute exposure to fluoroacetamide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to fluoroacetamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. RUSH to a health care facility.
4. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to fluoroacetamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. RUSH to a health care facility.
7. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
-------
EFATG
CAS Registry Number: 640-19-7
Page 3 of 3
FLUOROACETAMIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. RUSH to a health care facility.
3. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of f luoroacetamide is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of f luoroacetamide may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 5.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac-may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 644-64-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ DIMETILAN
CAS Registry Number: 644-64-4
Synonyms: l-Dimethylcarbamoyl-5-Methyl-3-Pyrazolyl Dimethylcarbamate;
2-(N,N-Dimethylcarbamyl)-3-Methylpyrazolyl-5 N,N-DimethyIcarbamate;
2-Dimethylcarbamoyl-3-Methyl-5-Pyrazolyl Dimethylcarbamate; Carbamic Acid,
Dimethyl-, l-((Dimethylamino)Carbonyl)-5-Methyl-lH-Pyrazol-3-yl Ester; Carbamic
Acid, Dimethyl-, Ester with 3-Hydroxy-N,N,5-Trimethylpyrazole-l- Carboxamide;
Dimethyl 2-Carbamyl-3-Methylpyrazolyldimethylcarbamate; Dimethylcarbamic Acid
1 -[(Dimethylamino)Carbonyl]-5-Methyl-lH-Pyrazol-3-yl Ester; Dimethylcarbamic
Acid Ester with 3-Hydroxy-N,N,5-Trimethylpyrazole-l- Carboxamide; Dimetilane;
ENT 25,922; Fly Bands; G 22870; G-22870; Geigy 22870; Geigy GS-13332; GS-13332;
Pyrazole-1-Carboxamide, 3-Hydroxy-N,N,5-Trimethyl-, Dimethyl Carbamate (Ester);
Snip; Snip Fly; Snip Fly Bands
Chemical Formula: C10H16N4O3
Molecular Weight: 240.27
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 25 mg/kg (*NIOSH/RTECS)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 392-410°F, 200-210°C at 13 mmHg (*Merck 1976)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.0001 at 20°C (*Worthing 1979)
Melting Point: 154-160°F, 68-71°C (*Merck 1976); technical grade
131-149°F, 55-65°C (Merck 1983, p. 476)
-------
CAS Registry Number: 644-64-4
Page 2 of 4
DIMETILAN
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Merck 1976)
Appearance and Odor: Colorless solid. The technical product is a yellow
to reddish-brown solid (Merck 1983, p. 476)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Very toxic; probable oral
lethal dose for humans is 50-500 mg/kg or between 1 teaspoon and 1 oz. for
a 70 kg (150 Ib.) person (*Gosselin 1976). Dimetilan is highly toxic by
ingestion and moderately toxic by contact with the skin (Sax 1984, p.
1145). Death is primarily due to respiratory arrest of central origin,
paralysis of the respiratory muscles, intense bronchoconstriction, or all
three. This compound is a cholinesterase inhibitor (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Carbamates) Extinguish fire
using agent suitable for types of surrounding fire, as the material itself
burns with difficulty. Use water in flooding quantities as a fog. Use
alcohol foam, carbon dioxide, or dry chemical (Student 1981, p. 104).
Special Fire Fighting Procedures: (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s.) Move container from fire area. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 644-64-4
Page 3 of 4
DIMETILAN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, jx 1145). (Non-Specific --
Carbamate Pesticide, Solid, n.o.s.) This material may burn but does not
ignite readily. Container may explode in heat of fire (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzed by acids and alkalis
(*Merck 1976).
Hazardous Decomposition or Byproducts: When heated to decomposition,
hazardous fumes of nitrogen oxides may be emitted (Sax 1984, p. 1145).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Formerly an insecticide for insect control on livestock, especially
housefly control. It is no longer produced commercially in the U.S. (*SRI;
Farm Chemicals Handbook 1984, p. C80)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Carbamate Pesticide, Solid, n.o.s.) Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind, keep out of
low areas. Do not touch spilled material, or breathe the vapors, dusts,
or fumes from burning materials. Do not handle broken packages
without protective equipment. Wash away any material that may have
contacted the body with soap and water (Student 1981, p. 104;
DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
-------
CAS Registry Number: 644-64-4
Page 4 of 4
DIMETILAN
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms are similar to carbaryl
poisoning: nausea, vomiting, abdominal cramps, diarrhea, pinpoint pupils,
excessive salivation, and sweating are common symptoms. Running nose and
tightness in chest are common in inhalation exposures. Difficulty in
breathing, raspy breathing, and loss of muscle coordination may also be
seen. Exposure may also result in random jerky movements, incontinence,
convulsions, and coma and death (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration.^If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 675-14-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ CYANURIC FLUORIDE
CAS Registry Number: 675-14-9
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 802) s-Triazine,
2,4,6-Trifluoro-; 2,4,6-Trifluoro-s-Triazine; 1,3,5-Triazine, 2,4,6-Trifluoro-
Chemical Formula: CSF3NS
Molecular Weight: 135.06
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.017 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 675-14-9
Page 2 of 3
CYANURIC FLUORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2649)
Skin: Yes (Sax 1984, p. 2649)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by skin contact and inhalation (Sax 1984, p. 2649).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of fluorides and nitrogen oxides (Sax 1984, p.
2649).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2649)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluoride and nitrogen oxides (Sax 1984, p. 2649).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
-------
CAS Registry Number: 675-14-9
Page 3 of 3
CYANURIC FLUORIDE
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Weast 1979
Hawley 1981
Arena 1979
Merck 1983
Encyc Occupat Health and Safety 1983
Gosselin 1984
Weiss 1980
CHRIS 1978
Hayes 1982
Student 1981
DOT 1984
Buchel 1983
Farm Chemicals Handbook 1984
U.S. Army 1975
-------
CAS Registry Number: 676-97-1
Page 1 of 4 ,
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHYL PHOSPHONIC BICHLORIDE
CAS Registry Number: 676-97-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 1J9): Phosphonic
Dichloride, Methyl-
Chemical Formula: CH3C12OP
Molecular Weight: 132.91
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.141 mg/Iiter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 676-97-1
Page 2 of 4
METHYL PHOSPHONIC BICHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (DOT 1984, Guide 39)
Skin: Yes (DOT 1984, Guide 39)
Ingestion: Yes (DOT 1984, Guide 39)
Health Hazards (Acute, Delayed, and Chronic): Poisonous if inhaled or
swallowed. Contact causes severe burns to skin and eyes (DOT 1984, Guide
39).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not get water inside container. Small fires:
dry chemical or carbon dioxide. Large fires: flood fire area with water
from a distance. Do not get solid stream of water on spilled material.
Move container from fire area if you can do so without risk. Spray cooling
water on containers that are exposed to flames until well after fire is out
(DOT 1984, Guide 39).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 39).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. May ignite other combustible materials (wood, paper, oil,
etc.). Reacts violently with water. Flammable poisonous gases may
accumulate in tanks and hopper cars. Runoff to sewer may create fire or
explosion hazard. Contact causes severe burns to skin and eyes. Runoff
from fire control or dilution water may cause pollution (DOT 1984, Guide
39).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 676-97-1
Page 3 of 4
METHYL PHOSPHONIC BICHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Violent reaction with water (DOT
1984, Guide 39)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapors (see Section III above). Do not get water inside
container; stop leak if you can do so without risk. Do not touch spilled
material. Use water spray to reduce vapors but do not put water on leak or
spill area. Keep combustibles (wood, paper, oil, etc.) away from spilled
material. Dike spill for later disposal; do not apply water unless
directed to do so. Clean up only under supervision of an expert (DOT 1984,
Guide 39).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. Speed in removing material from skin is of
extreme importance. In case of contact with material, immediately flush
-------
CAS Registry Number: 676-97-1
Page 4 of 4
*
METHYL PHOSPHONIC BICHLORIDE
SECTION IX (continued)
skin or eyes with running water for at least 15 minutes. Keep victim quiet
and maintain normal body temperature (DOT 1984, Guide 39).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Oilman 1985
-------
CAS Registry Number: 696-28-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENYL DICHLOROARSINE
CAS Registry Number: 696-28-6
Synonyms: Arsine, Dichlorophenyl-; Arsine, Dichloro(phenyl)-; Arsonous
Dichloride, Phenyl-; Dichlorophenylarsine; Phenylarsinedichloride; TL 69
Chemical Formula: C6H5AsCl2
Molecular Weight: 223
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(guinea pig) 4 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 489.9-495.7°F, 254.4-257.6°C (*Weast 1979)
Specific Gravity (H2O=1): 1.6516 at 19°C (*Weast 1979)
Vapor Pressure (mmHg): 0.033 at 25°C (U.S. Army 1975, p. 3-13)
Melting Point: -4°F, -20°C (*Hawley 1977)
Vapor Density (AIR=1): 7.7 (U.S. Army 1975, p. 3-13)
Evaporation Rate (Butyl acetate=l): 390 mg/m3 at 25°C (U.S. Army 1975, p.
3-13))
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor: Liquid -- microcrystalline (*Hawley 1977) odorless
(U.S. Army 1975, p. 3-14)
-------
CAS Registry Number: 696-28-6
Page 2 of 4
PHENYL DICHLOROARSINE
SECTION HI -- HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/ms, as arsenic (NIOSH
1987, p.54)
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: (Arsenic and compounds) NIOSH: 0.002 mg/ms,
15 minute ceiling (NIOSH 1987, p. 54). NIOSH occupational carcinogen
(NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 800)
Skin: Yes.(Hawley 1981, p. 800)
Ingestion: Yes (Hawley 1981, p. 800)
Health Hazards (Acute, .Delayed, and Chronic): Median lethal dosage 2600
mg-minute/ms. Mean incapacitating dosage 16 mg-minute/ms as a vomiting
agent and 1800 mg-minute/m3 as a blistering agent. 633 mg-minute/m3
produces eye injury (U.S. Army 1975, p. 3-14). Poisonous; may be fatal
if inhaled, swallowed, or absorbed through skin. Contact may cause
burns to skin and eyes (DOT 1984, Guide 55). Strong irritant to
eyes, skin, and tissue (*Hawley 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): High enough not to interfere with normal use
(U.S. Army 1975, p. 3-13)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, foam, or fog (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus. Move container from fire area if you can do it without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. Containers may explode in heat of fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 696-28-6
Page 3 of 4
PHENYL DICHLOROARSINE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (Decomposed by water) (Hawley 1981, p. 800)
Stable:
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Decomposed by water
(Hawley 1981, p. 800)
Hazardous Decomposition or Byproducts: Upon decomposition hydrogen
chloride and phenylarsenious oxide are emitted (U.S. Army 1975, p. 3-13).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used in organic synthesis, as a military tear gas, and a solvent
(Hawley 1981, p. 800).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Vomiting and blistering may occur (U.S.
Army 1975, p. 3-14).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
-------
CAS Registry Number: 696-28-6
Page 4 of 4
PHENYL DICHLOROARSINE
SECTION IX (continued)
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 732-11-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSMET
CAS Registry Number: 732-11-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, P. 145) Phosphorodithioic
Acid, O,O-Dimethyl Ester, S-Ester with N-(Mercaptomethyl)phthalimide; Imidan;
APPA; Decemthion; Decemthion P-6; (O,O-Dimethyl-
Phthalimidiomethyldithiophosphate); O,O-Dimethyl S-(N-Phthalimidomethyl)
Dithiophosphate; O,O-Dimethyl S-Phthalimidomethyl Phosphorodithioate;
ENT 25,705; Ftalophos; N-(Mercaptomethyl)Phthalimide S-(O,O-Dimethyl
Phosphorodithioate); Percolate; Phosphorodithioic Acid, S-((l,3-Dihydro-l,3-
Dioxo-2H-Isoindol-2-yl)Methyl) O,O-Dimethyl Ester; Phosmet; Phthalimide,
N-(Mercaptomethyl)-, S-Ester with O,O-Dimethyl Phosphorodithioate;
Phthalimidomethyl O,O-Dimethyl Phosphorodithioate; Phthalophos; PMP; Prolate; R
1504; Smidan; Stauffer R 1504
Chemical Formula: CnH12NO4PS2
Molecular Weight: 317.32
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.054 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes below boiling point (*Spencer 1982)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.001 at 122°F, 50°C (*Merck 1983)
Melting Point: 161°F, 71.9°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 732-11-6
Page 2 of 4
*
PHOSMET
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 25 mg/liter at 25°C (*Worthing 1979)
Appearance and Odor: Off-white crystalline solid (*Merck 1983), offensive
odor (*Spencer 1982).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Maximum air concentration in the USSR is 0.3
mg/m3 (Encyc Occupat Health and Safety 1983, p. 1643).
Routes of Entry: Inhalation: Yes (*NIOSH/RTECS 1985)
Skin: Yes (Encyc Occupat Health and Safety 1983,
p. 1643)
Ingestion: Yes (*NIOSH/RTECS 1985)
Health Hazards (Acute, Delayed, and Chronic): It is an organophosphorus
pesticide (Buchel 1983, p. 69). This material is very toxic; the probable
oral lethal dose for humans is 50-500 mg/kg, or between 1 teaspoon and 1
oz. for a 150 Ib. person. It is a cholinesterase inhibitor and has central
nervous system effects (Gosselin 1984, p. 11-298). Oral lethal doses in
humans have been reported at 50 mg/kg (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) This material may burn but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.). Stay upwind; keep out of low areas. Move container
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter
material. Wear positive pressure breathing apparatus and special
protective clothing (DOJT 1984, Guide 55).
-------
CAS Registry Number: 732-11-6
Page 3 of 4
PHOSMET
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific - Organophosphorus
Pesticide, n.o.s.). Container may explode in heat of fire. Fire and
runoff from fire control water may produce irritating or poisonous gases
(DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Clayton and Clayton 1981-82)
Conditions to Avoid: Storage above 113°F, 45°C, may lead to
decomposition (*Spencer 1982).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is an insecticide and acaricide (*Worthing 1979).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is an organophosphorus pesticide (Buchel 1983, p. 69). As for other
Organophosphorus pesticides stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Remove and isolate contaminated
clothing at the site. Do not touch spilled material. Use water spray to
reduce vapors. Take up small spills with sand or other noncombustible
absorbent material and place in containers for later disposal. Take up
small, dry spills with clean shovel and place in clean, dry container.
Dike far ahead of large spills for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 732-11-6
Page 4 of 4
PHOSMET
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 732-11-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHOSMET
(732-11-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form. - Colorless, crystalline solid.
Odor - Offensive.
Commercial Form - Pure off-white or pink solid (94 to 96%).
Use - Pesticide.
Caution: Phosmet may produce toxic gases when heated; containers may explode
in the heat of fire. Avoid sources of extreme heat.
Other Names - APPA, Decemthion, Ftalophos, Imidan, Imidathion, Percolate,
PMP, Prolate, Safidon, Simidan, Smidan, O,O-dimethyl S-phthalimidomethyl
phosphorodithioate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Phosmet Exposure:
Note: Phosmet is a cholinesterase inhibitor.
Acute exposure to phosmet may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
-------
EFATG
CAS Registry Number: 732-11-6
Page 2 of 3
PHOSMET
The heart rate may decrease following oral exposure or increase following
dermal exposure. Chest pain may be noted. Hypotension (low blood pressure)
may occur, although hypertension (high blood pressure) is not uncommon.
Dyspnea (shortness of breath) may be followed by respiratory collapse.
Giddiness is common.
Emergency Life-Support Procedures:
Acute exposure to phosmet may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosmet.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosmet.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
-------
EFATG
CAS Registry Number: 732-11-6
Page 3 of 3
PHOSMET
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions, from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of phosmet is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of phosmet may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 760-93-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHACRYLIC ANHYDRIDE
CAS Registry Number: 760-93-0
Synonyms: (SANSS 1983 Synonyms) 2-Propenoic Acid, 2-Methyl-, Anhydride;
Methacrylic Acid Anhydride; Methacryloyl Anhydride
Chemical Formula: C8H10OS
Molecular Weight: 154.17
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.45mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 192°F, 89°C at 5 mmHg (Weast 1979, p. C-465)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Weast 1979, p. C-465)
Appearance and Odor: Not Found
-------
CAS Registry Number: 760-93-0
Page 2 of 4
METHACRYLIC ANHYDRIDE
SECTION III « HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Methacrylic Acid) This material
may react violently with water. Small fires: dry chemical, carbon
dioxide, water spray, or foam. Large fires: water spray, fog, or foam.
Move container from fire area if you can do so without risk. Spray cooling
water on containers that are exposed to flames until well after fire is out
(DOT 1984, Guide 60).
Special Fire Fighting Procedures: (Non-Specific — Methacrylic Acid)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Wear self-contained (positive pressure if
available) breathing apparatus and full protective clothing (DOT 1984,
Guide 60).
Unusual Fire and Explosion Hazards: (Non-Specific — Methacrylic Acid)
This material may burn but may not ignite readily. Flammable/ poisonous
gases may accumulate in tanks and hopper cars. Some of these materials may
ignite combustibles (wood, paper, oil, etc.) (DOT 1984, Guide 60).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 760-93-0
Page 3 of 4
METHACRYLIC ANHYDRIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Methacrylic Acid) Do not touch spilled material; stop
leak if you can do so without risk. For small spills, absorb with sand or
other noncombustible absorbent material and place into containers for later
disposal. For large spills, dike far ahead of spill for later disposal
(DOT 1984, Guide 60).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Methacrylic Acid)
Move victim to fresh air; call emergency medical care. Remove and isolate
contaminated clothing and shoes at the site. In case of contact with
material, immediately flush skin or eyes with running water for at least 15
minutes. Keep victim quiet and maintain normal body temperature (DOT 1984,
Guide 60).
COMMENTS
Sources searched but no information found:
NIOSH/RTECS 1983
ACGIH 1983
NIOSH/OSHA 1978
-------
CAS Registry Number: 760-93-0
Page 4 of 4
METHACRYLIC ANHYDRIDE
COMMENTS (Continued)
Hawley 1981
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 786-19-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CARBOPHENOTHION
CAS Registry Number: 786-19-6
Synonyms: Phosphorodithioic Acid, S-(((p-Chlorophenyl)Thio)Methyl)
O,O-Diethyl Ester; Acarithion; Akarithion; Carbofenothion; Carbofenthion;
Dagadip; Endyl; ENT 23,708; Ethyl Carbophenothion; Garrathion; Hexathion;
Lethox; Nephocarp; O,O-Diethyl S-p-Chlorophenylthiomethyl Dithiophosphate;
Phosphorodithioic Acid, S-(((4-Chlorophenyl)Thio)Methyl) O,O-Diethyl Ester;
Phosphorodithioic Acid, S-(((p-Chlorophenyl)Thio)Methyl) O,O-Diethyl Ester;
R-1303; S-(((p-Chlorophenyl)Thio)Methyl) O,O-Diethyl Phosphorodithioate;
S-(4-Chlorophenylthiomethyl) Diethyl Phosphorothiolothionate; Stauffer R-1,303;
Trithion; Trithion Miticide
Chemical Formula: CnH16ClO2PSs
Molecular Weight: 342.85
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
6.8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 180°F, 82°C at 0.01 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.271 at 77°F, 25°C (*Merck 1976)
Vapor Pressure (mmHg): 0.0000003 at 68°F, 20°C (*Martin and Worthing 1974)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 786-19-6
Page 2 of 4
CARBOPHENOTHION
V
SECTION II (continued)
Solubility in Water: Practically insoluble (*Merck 1976); less than 4
mg/liter at 20°C (Hayes 1982, p. 394)
Appearance and Odor: Off-white to amber liquid, mild sulfur (rotten eggs)
like odor (*Martin and Worthing 1974).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not found
Routes of Entry: Inhalation: Yes (Non-Specific ~ Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Hayes 1982, p. 394)
Ingestion: Yes (Hayes 1982, p. 394)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic; the estimated fatal oral dose is 0.6 g for a 150 Ib. (70 kg) person
(*Arena 1974). It is an indirect cholinesterase inhibitor, meaning its
effects are on the nervous system (Hayes 1982, p. 394).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn, but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s) Stay upwind; keep out of low areas. Move
container from fire area if you can do it without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 786-19-6
Page 3 of 4
CARBOPHENOTHION
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide Liquid, n.o.s.) Container may explode in heat of fire. Fire and
runoff from fire control water may produce irritating or poisonous gases
(DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Martin 1974)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is an insecticide and acaricide, primarily for citrus crops
and deciduous fruits and nuts (*SRI; *Farm Chemicals Handbook 1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Do not touch spilled material; stop leak if you can do it without risk. Use
water spray to reduce vapors. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 786-19-6
Page 4 of 4
CARBOPHENOTHION
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms may include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
weakness, muscle twitching, difficult breathing, blurring or dimness of
vision, and loss of muscle coordination. Death may occur from failure of
the respiratory center, paralysis of the respiratory muscles, intense
bronchoconstriction, or all three (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 814-49-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIETHYL CHLOROPHOSPHATE
CAS Registry Number: 814-49-3
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 137) Phosphoro-
chloridic Acid, Diethyl Ester; Chlorophosphoric Acid, Diethyl Ester;
Diethoxyphosphorous Oxychloride
Chemical Formula: C4H10C1O3P
Molecular Weight: 172.56
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(rabbit) 7.9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 140°F, 60°C at 2 mmHg (Sax 1984, p. 1007)
Specific Gravity (H2O=1): 1.1915 at 25°C/25°C (Sax 1984, p. 1007)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 5.94 (Sax 1984, p. 1007)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Clear liquid (Sax 1984, p. 1007)
-------
CAS Registry Number: 814-49-3
Page 2 of 4
DIETHYL CHLOROPHOSPHATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 345)
Skin: Yes (Hawley 1981, p. 345)
Ingestion: Yes (Hawley 1981, p. 345)
Health Hazards (Acute, Delayed, and Chronic): This material is a
cholinesterase inhibitor. It has high oral and very high dermal toxicity.
It is a skin irritant (Sax 1984, p. 1007). It is also toxic by inhalation
(Hawley 1981, p. 345).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is combustible (Hawley 1981, p.
345). Methods for combustible liquids are as follows. Small fires: dry
chemical, carbon dioxide, water spray, or foam. Large fires: vater spray,
fog, or foam (DOT 1984, Guide 27).
Special Fire Fighting Procedures: Use the following procedures for
combustible liquids. Move container from fire area if you can do it
without risk. Cool containers that are exposed to flames with water from
the side until well after fire is out. For massive fire in cargo area, use
unmanned hose holder or monitor nozzles; if this is impossible, withdraw
from area and let fire burn. Withdraw immediately in case of rising sound
from venting safety device or any discoloration of tank due to fire. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Wear self-contained (positive pressure if
available) breathing apparatus and full protective clothing. Isolate for
1/2 mile in all directions if tank car or truck is involved in fire (DOT
1984, Guide 27).
Unusual Fire and Explosion Hazards: Emits very toxic fumes of chloride
and phosphorus oxides when heated to decomposition (Sax 1984, p. 1007).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 814-49-3
Page 3 of 4
DIETHYL CHLOROPHOSPHATE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits very toxic fumes of chloride
and phosphorus oxides when heated to decomposition (Sax 1984, p. 1007).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an intermediate in organic synthesis (Hawley 1981,
p. 345).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Do not breathe vapors (see Section III
above). This material is a combustible liquid (Hawley 1981, p. 345). For
a spill or leak of a combustible liquid, shut off ignition sources; no
flares, smoking or flames in hazard area. Stop leak if you can do so
without risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal. Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas (DOT 1984, Guide 27).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 814-49-3
Page 4 of 4
DIETHYL CHLOROPHOSPHATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 814-49-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIETHYL CHLOROPHOSPHATE
(814-49-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Water-white liquid.
Use - Chemical intermediate.
Caution: Avoid sources of extreme heat including fire. Diethyl
chlorophosphate will liberate toxic phosphorus oxide fumes and hydrogen
chloride gas when heated to decomposition.
Other Names - Chlorophosphoric acid, diethyl ester; diethoxyphosphorous
oxychloride; diethyl phosphorochloridate; phosphorochloridic acid, diethyl
ester.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, atropine,
pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Diethyl Chlorophosphate Exposure:
Note: Diethyl chlorophosphate is a cholinesterase inhibitor.
Acute exposure to diethyl chlorophosphate may produce the following signs and
symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms,
and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma
may also occur.
-------
EFATG
CAS Registry Number: 814-49-3
Page 2 of 3
DIETHYL CHLOROPHOSPHATE
The heart rate may either decrease following oral exposure or increase
following dermal exposure. Chest pain may be noted. Hypotension (low blood
pressure) may be observed, although hypertension (high blood pressure) is not
uncommon. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Diethyl chlorophosphate may
severely irritate or burn the skin, eyes, or mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to diethyl chlorophosphate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to diethyl chlorophosphate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
piocedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to diethyl chlorophosphate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
-------
EFATG
CAS Registry Number: 814-49-3
Page 3 of 3
DIETHYL CHLOROPHOSPHATE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 814-68-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ACRYLYL CHLORIDE
CAS Registry Number: 814-68-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 276) Acrylic Acid
Chloride; Acryloyl Chloride; Propenoyl Chloride; 2-Propenoyl Chloride
Chemical Formula: C3H3C1O
Molecular Weight: 90.51
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.092 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 167°F, 75°C (Hawley 1981, p. 17)
Specific Gravity (H2O=1): 1.1136 at 20°C/4°C (Weast 1979, p. C-465)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Liquid (Hawley 1981, p. 17)
-------
CAS Registry Number: 814-68-6
Page 2 of 3
ACRYLYL CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 134)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Decomposes in water (Weast 1979, p.
C-465).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides (Sax 1984, p. 134).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 814-68-6
Page 3 of 3
ACRYLYL CHLORIDE
SECTION VI -- USE INFORMATION
Monomer; intermediate (Hawley 1981, p. 17).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section HI above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Merck 1983
Weiss 1980
NIOSH/OSHA 1978
ACGIH 1983
Gosselin 1984
Encyc Occupat Health and Safety 1983
DOT 1984
NFPA 1984
Student 1981
Verschueren 1983
-------
CAS Registry Number: 88-05-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ANILINE, 2,4,6-TRIMETHYL-
CAS Registry Number: 88-05-1
Synonyms: 2,4,6-Trimethylaniline; 2-Aminomesitylene; Aminomesitylene;
Benzenamine, 2,4,6-Trimethyl-; Mesidin; Mesidine; Mesitylamine; Mesitylene,
2-Amino-
Chemical Formula: C9H13N
Molecular Weight: 135.2
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.29 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 450-451°F, 232-233°C (Weast 1980, p. C-148)
Specific Gravity (H2O=1): 0.9633 (Weast 1980, p. C-148)
Vapor Pressure (mmHg): Not Found
Melting Point: 23°F, -5°C (Weast 1980, p. C-148)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 88-05-1
Page 2 of 4
ANILINE, 2,4,6-TRIMETHYL-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2661)
Health Hazards (Acute, Delayed, and Chronic): This material is moderately
toxic orally. It is also considered highly toxic by unspecified routes.
It is a skin and eye irritant (Sax 1984, p. 2661). Suspect occupational
carcinogen (Clayton and Clayton 1981-82, p. 2892). (Non-Specific -
Aromatic Amines) The danger of acute poisoning is represented by
methemoglobinemia leading to adverse effects on the red cells. A number of
the amines may act as skin sensitizers (Encyc Occupat Health and Safety
1983, p. 142).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Poisonous Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray or foam. Large fires:
water spray, fog or foam. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific ~ Poisonous Liquid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. If water pollution occurs, notify appropriate
authorities (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2661).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 88-05-1
Page 3 of 4
ANILINE, 2,4,6-TRIMETHYL-
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2661)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2661).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poisonous Liquid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII « PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Repeated exposure results in narrowing of
peripheral vision, increase in size of blind spot and decrease in
photosensitivity (*Grant 1974).
Emergency and First Aid Procedures: (Non-Specific — Poisonous Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
-------
CAS Registry Number. 88-05-1
Page 4 of 4
ANILINE, 2,4,6-TRIMETHYL-
SECTION IX (continued)
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed, keep victim under observation (DOT
1984, Guide 55).
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CAS Registry Number: 88-85-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DINOSEB
CAS Registry Number: 88-85-7
Synonyms: 2,4-Dinitro-6-( 1 -Methylpropyl)Phenol; 2,4-Dinitro-6-sec-
Butylphenol; 2-(l-Methylpropyl)-4,6-Dinitrophenol; Phenol, 2-sec-Butyl-4,6-
Dinitro-; 4,6-Dinitro-2-(l-Methyl-n-Propyl)Phenol; 4,6-Dinitro-2-
sec-Butylphenol; 4,6-Dinitro-o-sec-Butylphenol; AATOX; Aretit; Basanite; BNP
20; BNP 30; Butaphene; Caldon; Chemox General; Chemox PE; DBNF; Dibutox;
Dinitrall; Dinitro Weed Killer; Dinitro-Ortho-Sec-Butyl Phenol;
Dinitrobutylphenol; Phenol, 2-(l-Methylpropyl)-4,6-Dinitro-; DN 289; DNBP;
DNOSBP; DNSBP; Dow General; Dow General Weed Killer; Dow Selective Weed Killer;
Dytop; Elgetol; Elgetol 318; ENT 1,122; Gebutox; Hivertox; Kiloseb; Knoxweed;
Ladob; Laseb; Nitropone; Phenol, 2-(l-Methylpropyl)-4,6-Dinitro-; Phenol,
2-sec-Butyl-4,6-Dinitro-; Premerg; Sinox General; Subitex
Chemical Formula: C10H12N2O5
Molecular Weight: 240.2
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(mouse) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.2647 at 45°C (*Weed Science Society of
America 1979)
Vapor Pressure (mmHg): 1 at 151.1°C (*Weed Science Society of America
1979)
Melting Point: 100-108°F, 38-42°C (Merck 1983, p. 479)
-------
CAS Registry Number: 88-85-7
Page 2 of 4
DINOSEB
SECTION II (continued)
Vapor Density (AIR=1): 7.73 (Sax 1984, p. 582)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.0052 g/100 ml (*Weed Science Society of America
1979)
Appearance and Odor: Orange-brown viscous liquid (Merck 1983, p. 479);
pungent odor (*Weed Science Society of America 1979) or crystals (*Sax
1979); orange solid when pure; technical grade is orange-brown solid
(Worthing 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Weed Science Society of America
1979)
Skin: Yes (Hawley 1981, p. 374)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic: Probable
oral lethal dose is 5-50 mg/kg; between 7 drops and 1 teaspoonful for 70 kg
* person .(ISO Ib.) (Gosselin 1976, p. 11-197).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 60.1°F to 84.9°F, 15.6°C to 29.4°C for 3
commercial products (*Weed Science Society of America 1979)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is a dinitrophenol herbicide (Buchel
1983, p. 304). (Non-Specific -- Dinitrophenol, Flammable Solid)
Extinguish by flooding with water. Cool all affected containers with
flooding quantities of water. Apply water from as far a distance as
possible (Student 1981, p. 205).
Special Fire Fighting Procedures: This is a dinitrophenol herbicide
(Buchel 1983, p. 304). (Non-Specific -- Dinitrophenol, Flammable Solid)
Wear self-contained breathing apparatus and full protective clothing. If
-------
CAS Registry Number: 88-85-7
Page 3 of 4
DINOSEB
SECTION IV (continued)
fire becomes uncontrollable, evacuate for a radius of 5000 feet (Student
1981, p. 206).
Unusual Fire and Explosion Hazards: This is a dinitrophenol herbicide
(Buchel 1983, p. 304). (Non-Specific -- Dinitrophenol, Flammable Solid).
It is dangerously explosive. When not water wet it is a high explosive.
Dry, the material is easily ignited and it will burn very vigorously
(Student 1981, p. 205).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Kearney 1975)
Conditions to Avoid: Appear to be stable in acid solution, but are
susceptible to decomposition by ultraviolet radiation in alkaline
solution (*Kearney 1975).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: On decomposition, nitro compounds
such as this emit toxic fumes (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Plant growth regulator; insecticide and herbicide (Hawley 1981, p. 374).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is a dinitrophenol herbicide (Buchel 1983, p. 340). (Non-Specific --
Dinitrophenol, Flammable Solid) Do not handle broken packages without
protective equipment. Wash away any material which may have contacted the
body with copious amounts of water. Keep sparks, flames, and other sources
of ignition away. Keep material out of water sources and sewers. Keep
spilled material wet. Do not attempt to sweep up dry material
(Student 1981, p. 206).
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CAS Registry Number: 88-85-7
Page 4 of 4
DINOSEB
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 88-85-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
DINOSEB
(88-85-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Dark orange viscous liquid or dark brown crystals.
Odor - Pungent.
Commercial Forms - Orange-brown emulsifiable concentrate or oil solution.
Uses - Plant growth regulator, pesticide.
Material to Avoid - Alkali.
Other Names - AATOX, Aretit, Basanite, Butaphene, Caldon, Chemox General,
Dibutox, Dinitrall, dinitrobutylphenol, Dow General, Dytop, Elgetol, Hivertox,
Kiloseb, Knoxweed, Nitropone, Premerg, Sinox General, Subitex.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Dinoseb Exposure:
Warning: Effects may be delayed from several hours to 2 days. Caution is
advised. Toxicity of dinoseb is enhanced by high ambient temperature and
physical activity.
Early manifestations of dinoseb exposure include fever, sweating, headache, and
confusion. Elevations of blood pressure, pulse, and respiratory rate are
common. Severe exposure may result in restlessness, seizures, and coma.
Other signs and symptoms include dyspnea (shortness of breath), pulmonary
edema, nausea, vomiting, and abdominal pain. Liver injury with associated
jaundice, kidney failure, and cardiac arrhythmias may be noted. Muscle
weakness may be pronounced. Dermal exposure results in yellow staining of the
skin and may produce burns,.
-------
EFATG
CAS Registry Number: 88-85-7
Page 2 of 3
DINOSEB
Emergency Life-Support Procedures:
Acute exposure to dinoseb may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dinoseb.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dinoseb.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes. .
5. Vigorously wash exposed skin areas with soap and water. Yellowish
coloration usually accompanies dermal exposure; the discoloration does not
have to be fully removed to prevent further absorption.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 88-85-7
Page 3 of 3
DINOSEB
Ingestion Exposure:
•1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of dinoseb is unknown or suspected to be greater than 30
minutes, do not induce vomiting and proceed to Step 4. Ipecac should not
be administered to children under 6 months of age.
Warning: Ingestion of dinoseb may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate, and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2
oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 91-08-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TOLUENE 2,6-DHSOCYANATE
CAS Registry Number: 91-08-7
Synonyms: 2,6-Toluene Diisocyanate; l,3-Diisocyanato-2-Methylbenzene;
2,6-Diisocyanato-1 -Methylbenzene; 2,6-Diisocyanatotoluene; 2,6-TDI;
2-Methyl-m-Phenylene Isocyanate; 2-Methyl-meta-Phenylene Isocyanate; Benzene,
2,6-Diisocyanato-1-Methyl-; Hylene TCP A; Hylene TIC; Hylene TM; Hylene TM-65;
Hylene TRF; Isocyanic Acid, 2-Methyl-m-Phenylene Ester; Isocyanic Acid,
2-Methyl-meta-Phenylene Ester; m-Tolylene Diisocyanate; meta-Tolylene
Diisocyanate; NIAX TDI; NIAX TDI-P; Tolylene 2,6-Diisocyanate
Chemical Formula: C9H6N2O2
Molecular Weight: 174.2
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.091 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 264-271°F, 129-133°C at 18 mmHg (*IARC 1972-1985)
Specific Gravity (H2O=1): 1.22 at 25°C for a 80% 2,4:20% 2,6 TDI mixture
(*ACGIH 1980)
Vapor Pressure (mmHg): 0.5 at 25°C for a 80% 2,4:20% 2,6 TDI mixture
(*ACGIH 1980)
Melting Point: 68-72°F, 20-22°C for a 80% 2,4:20% 2,6 TDI mixture (*ACGIH
1980)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 91-08-7
Page 2 of 4
TOLUENE 2,6-DIISOCYANATE
SECTION II (continued)
Solubility in Water: Not Found
Appearance and Odor: Not Found
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 1030)
Skin: Yes (Hawley 1981, p. 1030)
Ingestion: Yes (Hawley 1981, p. 1030)
Health Hazards (Acute, Delayed, and Chronic): Classified as slightly
toxic orally. Probable oral lethal dose in humans is 5 to 15 g/kg or
between 1 pint and 1 quart for a 70 (150 Ib.) person (*Gosselin 1976).
Particularly poisonous when breathed. This is among the most poisonous of
isocyanates (*Lefaux 1968). Acute and chronic exposures to low
concentrations may produce asthmatic attacks (Doull 1980, p. 533).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 270°F, 132°C for a 80% 2,4:20% 2,6 TDI mixture
(*ACGIH 1980)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Should be extinguished with carbon dioxide, dry
chemical or inert gas. For large fires fight with water in the form of
spray (*Encyc Occupat Health and Safety 1981).
Special Fire Fighting Procedures: Should wear a self-contained breathing
apparatus (*Encyc Occupat Health and Safety 1971). Move container from
fire area if you can do so without risk. Spray cooling water on containers
that are exposed to flames until well after fire is out. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 57).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1084). Ventilation
should be adequate. If polyurethane products are heated, protection
against isocyanate release is necessary (*Encyc Occupat Health and
Safety 1971).
-------
CAS Registry Number: 91-08-7
Page 3 of 4
TOLUENE 2,6-DIISOCYANATE
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1084)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1084).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Manufacturing of polyurethane foams, elastomers, and coatings; crosslinking
agent for nylon 6 (*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Decontaminate with a suitable solution such as 10 percent ammonia with
alcohol (*Encyc Occupat Health and Safety 1971). Keep unnecessary people
away, isolate hazard area and deny entry. Stay upwind and keep out of low
areas. Ventilate closed spaces before entering them. Shut off
ignition sources; no flares, smoking or flames in hazard area. Do not
touch spilled material, stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
noncombustible material and place into containers for later disposal.
Small dry spills: with clean shovel place material into clean dry
container and- cover; move containers from spill area. Large spills: dike
far ahead of spill for later disposal (DOT 1984, Guide 57).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 91-08-7
Page 4 of 4
TOLUENE 2,6-DIISOCYANATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 91-08-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
TOLUENE 2,6-DIISOCYANATE
(91-08-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Water-white to pale yellow liquid.
Odor - Sharp, pungent.
Commercial Forms - Liquid in drums or tank cars.
Uses - Cross-linking agent for nylon; manufacture of polyurethane foams,
elastomers, and coatings.
Materials to Avoid - Water (except for use in emergency life support).
Caution: Mixing with water may result in a violent reaction. Sources of
extreme heat or ignition (including sparks or fire) may result in the formation
of toxic nitrogen oxide gases.
Other Names - Hylene TCPA, m-Tolylene diisocyanate, Niax TDI.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Toluene 2,6-Diisocyanate Exposure:
Warning: Toluene 2,6-diisocyanate is a powerful irritant to the lungs, skin,
eyes, and gastrointestinal tract. Caution is advised.
Signs and symptoms of acute exposure to toluene 2,6-diisocyanate may be severe
and include burning of the skin, eyes, nose, and throat. Cough, laryngitis,
chest pain, tightness in the chest, bronchitis, asthma, emphysema, and
enlargement of the right side of the heart may also occur. Gastrointestinal
effects may include vomiting and abdominal pain. Headache, insomnia, euphoria,
depression, anxiety, paranoia, neuroses, and ataxia (incoordination) may also
be noted.
-------
EFATG
CAS Registry Number: 91-08-7
Page 2 of 3
TOLUENE 2,6-DIISOCYANATE
Emergency Life-Support Procedures:
Acute exposure to toluene 2,6-diisocyanate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to toluene 2,6-diisocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to toluene 2,6-diisocyanate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 91-08-7
Page 3 of 3
TOLUENE 2,6-DIISOCYANATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Give the victims water or milk: children up to I year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. RUSH to a health care facility.
-------
CAS Registry Number: 95-48-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CRESOL, -o
CAS Registry Number: 95-48-7
Synonyms: o-Cresol; l-Hydroxy-2-Methylbenzene; 2-Cresol; 2-Hydroxytoluene;
2-Methylphenol; o-Cresylic Acid; o-Hydroxytoluene; o-Methylphenol;
o-Methylphenylol; o-Oxytoluene; o-Toluol; Orthocresol; Phenol, 2-Methyl-
Chemical Formula: C7H8O
Molecular Weight: 108.15
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.179 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 376°F, 191°C (*Weast 1979)
Specific Gravity (H2O=1): 1.047 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at 38.2°C (*Sax 1979)
Melting Point: 88°F, 31°C (*Weast 1979)
Vapor Density (AIR=1): 3.72 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 40 parts water (*Merck 1983)
Appearance and Odor: Colorless liquid (NFPA 1978, p. 49-32), colorless
crystalline compound (*Clayton and Clayton 1981-82) or white crystals
(*Hawley 1981) with phenolic odor (*Merck 1983)
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CAS Registry Number: 95-48-7
Page 2 of 4
CRESOL, -o
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 ppm (22 mg/ms) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 5 ppm (22 mg/ms) (skin) (*ACGIH 1983)
IDLH: 250 ppm (NIOSH/OSHA 1978, p. 72)
Other Limits Recommended: NIOSH: 2.3 ppm (10mg/ms) 10-hour TWA (NIOSH
1987, p. 86)
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Merck 1983)
Health Hazards (Acute, Delayed, and Chronic): The chemical is rated as a
very toxic compound with a probable oral lethal dose in humans of 50-500
mg/kg, or between I teaspoon and 1 ounce for a 70 kg (150 Ib.) person
(*Gosselin 1976). It is a strong dermal irritant and frequently causes
dermatitis. Serious or fatal poisoning may result if large areas of skin
are wet with cresol, o- and the substance is not removed immediately
(*ACGIH 1980). Ingestion of even a small amount may cause paralysis and
coma (*Merck 1983). It is corrosive to body tissues (NFPA 1978, 49-32)
with toxicity similar to phenol (Encyc Occupat Health and Safety 1983,
p. 569).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 81-83°C (*Merck 1983)
Flammable Limits:
LEL: 1.4% at 300°F (*Sax 1979)
UEL: Not Found
Extinguishing Methods: Water to blanket the fire and dry chemical, foam,
or carbon dioxide to extinguish the flames (*NFPA 1978). Extinguish small
fires with dry chemical, carbon dioxide, water spray, or foam. For large
fires use water spray, fog, or foam. Move container from fire area if you
can do so without risk (*DOT 1984).
Special Fire Fighting Procedures: Use water to keep fire-exposed
containers cool (*NFPA 1978). Fight fire from a maximum distance. Dike
fire control water for later disposal; don't scatter the material. Wear
positive pressure breathing apparatus and full protective clothing. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site (*DOT 1984).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases. Runoff from fire control water may give off poisonous
gases. This material may burn but does not ignite readily. Container may
explode in heat of fire (*DOT 1984). Slight explosion and fire hazard in
the form of vapor when exposed to heat or flame (Sax 1984, p. 814).
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CAS Registry Number: 95-48-7
Page 3 of 4
CRESOL, -o
SECTION IV (continued)
NFPA Flammability Rating: 2
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Reacts violently with nitric acid,
oleum, and chlorosulfonic acid (Sax 1984, p. 814).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes (*Sax 1979).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 279)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chemical intermediate for phenolic and epoxy resins, sulfur chromium dyes,
herbicides, magnet wire coatings, and Pharmaceuticals; disinfectant;
solvent; fiber treatment agent; tanning agent; and metal degreasing agent
(*SRI).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). Keep unnecessary people away;
isolate the hazard area and deny entry. Do not touch spilled
material. Stop leak if you can do so without risk. Use water spray to
reduce vapors. For small spills, absorb the material with sand or other
noncombustible absorbent material and place into containers for later
disposal. For small dry spills, shovel up and place into clean, dry
containers and cover. For large spills, dike far ahead of spill for later
disposal. If clothing becomes contaminated remove immediately and isolate
at the site (*DOT 1984). If a leak or spill has not ignited, use water
spray to disperse the vapors and to provide protection for personnel
attempting to stop a leak. Water spray may be used to flush spills away
from exposures (NFPA 1978, p. 49-32).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
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CAS Registry Number: 95-48-7
Page 4 of 4
CRESOL, -o
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene POOR/LIMITED*
CPE GOOD/LIMITED*
PE POOR/LIMITED
PVC POOR/LIMITED*
Saranex GOOD/LIMITED
' Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 95-48-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
o-CRESOL
(95-48-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless liquid or white crystals below 31 degrees C
(88 degrees F).
Odor - Phenollike.
Commercial Forms - Shipped in glass bottles, 10- and 55-gallon metal drums,
55-gallon metal barrels, tank trucks, tank cars, and tank barges.
Uses - Manufacture of resins, coatings, dyes, herbicides, Pharmaceuticals;
fiber treatment, tanning, metal degreasing; disinfectant; solvent.
Other Names - Cresylic acid, 2-methylphenol, o-hydroxytoluene, orthocresol, o-
oxytoluene.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, polyethylene glycol 300 or 400, water,
milk, activated charcoal, saline cathartic or sorbitol, normal saline, D5W,
Ringer's lactate, castor oil, diazepam, phenytoin, phenobarbital, 1% methylene
blue.
Signs and Symptoms of Acute o-Cresol Exposure:
Warning: Effects may be delayed. Caution is advised. Vital signs should be
monitored closely.
Signs and symptoms of acute exposure to o-cresol may include a weak pulse,
hypotension (low blood pressure), tachycardia (rapid heart rate), cardiac
arrhythmias, and cardiac failure. Tachypnea (rapid respiratory rate),
pulmonary edema, and respiratory arrest or failure may be noted.
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EFATG
CAS Registry Number: 95-48-7
Page 2 of 3
o-CRESOL
Weakness, headache, dizziness, tinnitus (ringing in the ears), shock, and
delirium are common. Seizures may occur and are often followed by coma.
Pallor, sweating, dilated pupils, and a profound drop in body temperature may
also be found. Gastrointestinal effects include nausea, abdominal pain, bloody
vomitus, and bloody diarrhea. Renal insufficiency may lead to hematuria
(bloody urine).
o-Cresol is corrosive to the skin, eyes, and mucous membranes. Contact may
result in severe and painful burns, which promptly become anesthetized (numb)
to touch and pain. Ulceration may occur.
Emergency Life-Support Procedures:
Acute exposure to o-cresol may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to o-cresol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to o-cresol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
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EFATG
CAS Registry Number: 95-48-7
Page 3 of 3
o-CRESOL
5. Wash exposed skin areas with undiluted polyethylene glycol 300 or 400. If
polyethylene glycol is unavailable, use water. Follow initial
polyethylene glycol or water wash with a second (water) wash.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide'
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Immediately give conscious and alert victims water or milk: children up
to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years, 200 mL
(6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Do not exceed 250 mL
(8 oz or 1 cup).
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 97-18-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENOL, 2,2'-THIOBIS(4,6-DICHLORO-
CAS Registry Number: 97-18-7
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 77): Actamer; Bidiphen;
bis(2-Hydroxy-3,5-Dichlorophenyl) Sulfide; Bithionol; Bithionol Sulfide; Bitin;
CP 3438; 2,2'-Dihydroxy-3,3',5,5'-Tetrachlorodiphenylsulfide;
2-Hydroxy-3,5-Dichlorophenyl Sulphide; Lorothidol; Lorothiodol; NCI-C60628;
Neopellis; TBP; USAF B-22; XL 7; 2,2'-Thiobis(4,6-Dichlorophenol); Vancide BL
Chemical Formula: C12H6C14O2S
Molecular Weight: 356.04
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.73 at 25°C/4°C (Merck 1983, p. '182)
Vapor Pressure (mmHg): 0.0000000011 at 37°C (Merck 1983, p. 182)
Melting Point: 370°F, 188°C (Merck 1983, p. 182)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (Merck 1983, p. 182)
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CAS Registry Number: 97-18-7
Page 2 of 4
PHENOL, 2,2'-THIOBIS(4,6-DICHLORO-
SECTION II (continued)
Appearance and Odor: White or grayish-white powder with an odorless to
phenolic odor (Hawley 1981, p. 137).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Non-Specific - Phenol) (Gosselin 1976,
p. III-272)
Ingestion: Yes (Sax 1984, p. 2567)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
slightly toxic. Probable oral lethal dose for humans is 5-15 g/kg for a 70
kg (150 Ib) person. The toxicity of this compound is similar to that of
phenol (Gosselin 1984, p. 11-193). Major hazard of phenol poisoning stems
from its systemic effects which include central nervous system depression
with coma, hypothermia, loss of vasoconstricter tone, cardiac depression
and respiratory arrest (Gosselin 1984, p. III-345).
Medical Conditions Generally Aggravated by Exposure: Not Found
.SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2567)
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CAS Registry Number: 97-18-7
Page 3 of 4
PHENOL, 2,2'-THIOBIS(4,6-DICHLORO-
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits very toxic fumes of
chlorine-containing compounds and sulfur oxides when heated to
decomposition (Sax 1984, p. 2567).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
It is used as a surfactant-formulated antimicrobial against bacteria, molds
and yeast. It is proposed as an agricultural fungicide (Merck 1983, p.
182). Other uses include deodorant, germicide, fungistat and in the
manufacture of Pharmaceuticals (Hawley 1981, p. 137). It is no longer
allowed to be used in cosmetics (Merck 1983, p. 182). A food additive in
feed and drinking water of animals. Also a food additive permitted in food
for human consumption (Sax 1984, p. 2567).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Phenol, Solid) Keep unnecessary people away and stay
upwind. Do not touch spilled material. Use water spray to reduce vapors.
Absorb spills with non-combustible absorbent material. For large spills
dike far ahead for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Phenol) Symptoms
include burning pain in mouth and throat; white necrotic lesions in mouth,
esophagus and stomach; abdominal pain; vomiting; bloody diarrhea; paleness;
sweating; weakness; headache; dizziness; tinnitus; scanty, dark-colored
urine; weak irregular pulse and shallow respiration (Gosselin 1984, p.
III-346).
Emergency and First Aid Procedures: (Non-Specific -- Phenol, Solid) Move
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
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CAS Registry Number: 97-18-7
Page 4 of 4
PHENOL, 2,2'-THIOBIS(4,6-DICHLORO-
SECTION IX (continued)
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site (DOT 1984, Guide 55).
COMMENTS:
Sources searched but no information found:
Hayes 1982
Farm Chemicals Handbook 1984
NFPA 1984
CHRIS 1978
Weiss 1980
Encyc of Occupat Health and Safety 1983
Student 1981
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CAS Registry Number: 98-05-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985 v
Revision: November 30, 1987
CHEMICAL IDENTITY -- BENZENEARSONIC ACID
CAS Registry Number: 98-05-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 542) Phenyl arsenic
acid; Phenylarsonic acid
Chemical Formula: C6H7AsO3
Molecular Weight: 202.05
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (mouse)
0.27 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.760 (Sax 1984, p. 362)
Vapor Pressure (mmHg): Not Found
Melting Point: 320°F, J60°C, decomposes (Sax 1984, p. 362;
Merck, 1983, p.1067)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 40 parts water (Merck 1983, p. 151)
(Sax 1984, p. 362)
Appearance and Odor: Colorless solid (Sax 1984, p. 362).
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CAS Registry Number: 98-05-5
Page 2 of 4
BENZENEARSONIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/ms, as Arsenic
(NIOSH 1987, p.54)
ACGIH TLV: (Soluble arsenic compounds) TWA 0.2 mg/ms, as Arsenic
(ACGIH 1984, p. 10)
IDLH: Not Found
Other Limits Recommended: NIOSH: (Arsenic and compounds) 0.02 mg/ms,
as Arsenic, 15 minute ceiling (NIOSH 1987, p.54)
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Hawley 1981, p. 799)
Health Hazards (Acute, Delayed, and Chronic): Benzenearsonic acid is a
deadly poison (Sax 1984, p. 342). (Non-Specific -- Arsenic Compounds)
Chronic exposure to arsenic compounds can cause dermatitis and digestive
disorders (Clayton and Clayton 1981-82, p. 1522). Renal damage may develop
(Gosselin 1981, p. HI-43).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Arsenical Compound, Solid,
n.o.s.) This material does not burn or burns with difficulty. Extinguish
fire using agent suitable for surrounding fire (Student 1981, p. 51).
Special Fire Fighting Procedures: (Non-Specific ~ Arsenical Compound,
Solid, n.o.s.) Use water in flooding quantities as fog. Avoid breathing
dusts and fumes; keep upwind; wear self-contained breathing apparatus
(Student 1981, p. 51).
Unusual Fire and Explosion Hazards: Benzenearsonic acid emits poisonous
fumes of arsenic when heated to decomposition (Sax 1984, p. 362).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
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CAS Registry Number: 98-05-5
Page 3 of 4
BENZENEARSONIC ACID
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition
(320°F), it emits toxic arsenic fumes (Sax 1984, p. 362).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as an analytical reagent for tin (Merck 1983, p. 151).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Arsenic Compound, Solid, n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Do not touch spilled material; stop leak if you can do it without
risk. Small spills: take up with Sand or other noncombustible absorbent
material and place into containers for later disposal. Small dry spills:
with clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Arsenic) Symptoms of
arsenic poisoning usually appear one-half to one hour after ingestion, but
may be delayed many hours. Symptoms include a sweetish metallic taste and
garlicky odor; difficulty in swallowing; abdominal pain; vomiting and
painful diarrhea; dehydration, thirst, and cramps; dizziness, stupor, and
delirium, rapid heart beat, headache, skin disorders, and coma (Gosselin
1981, p. HI-45).
Emergency and First Aid Procedures: (Non-Specific -- Arsenic Compound,
Solid, n.o.s.) Move victim to fresh air; call emergency medical care.
Remove and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes (DOT J984, Guide 53).
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CAS Registry Number: 98-05-5
Page 4 of 4
BENZENEARSONIC ACID
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Arena 1979
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CAS Registry Number: 98-07-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date:.October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - BENZOTRICHLORIDE
CAS Registry Number: 98-07-7
Synonyms: Toluene, alpha,alpha,alpha-Trichloro-; (Trichloromethyl)Benzene;
l-(Trichloromethyl) Benzene; alpha,alpha,alpha-Trichlorotoluene; Benzene,
(Trichloromethyl)-; Benzenyl Chloride; Benzenyl Trichloride; Benzoic
Trichloride; Benzyl Trichloride; Benzylidyne Chloride; omega,omega,omega-
Trichlorotoluene; Phenylchloroform; Phenyltrichloromethane; Toluene
Trichloride; Trichloromethylbenzene; Trichlorophenylmethane
Chemical Formula: C7H5C1S
Molecular Weight: 195.48
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.064 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 429.4°F, 220.8°C (*Merck 1983)
Specific Gravity (H2O=1): 1.3756 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at 45.8°C; 10 at 87.6°C (*Weast 1979)
Melting Point: 23°F, -5.0°C (*Merck 1983)
Vapor Density (AIR=1): 6.77 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Merck 1983)
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CAS Registry Number: 98-07-7
Page 2 of 4
BENZOTRICHLORIDE
SECTION II (continued)
Appearance and Odor: Material is a clear, colorless to yellowish, oily
liquid with a penetrating odor (*IARC 1972-1985; *Sax 1979; *Hawley 1981)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Not Found
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Toxic by inhalation; fumes
are highly irritating to skin and mucous membranes (*Merck 1983, Hawley
1981, p. 119). May cause death or permanent injury after very short
exposure to small quantities (*Sax 1975). A suspected carcinogen (*Sorahan
1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 260°F, 127°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam. Cool containers
that are exposed to flames with water from the side until well after the
fire is out (DOT 1984, Guide 60).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing (DOT 1984, Guide 60). Normal fire fighting
procedures may be used (*NFPA 1978).
Unusual Fire and Explosion Hazards: This material may react violently
with water. Fire may produce irritating or poisonous gases.
Flammable/poisonous gases may accumulate in tanks and hopper cars.
Materials may ignite combustibles (wood, paper, oil, etc.) (*DOT 1984).
NFPA Flammability Rating: 1
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CAS Registry Number: 98-07-7
Page 3 of 4
BENZOTRICHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1983)
Stable:
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Similar to hydrochloric acid;
material will react with water or steam to produce toxic and corrosive
fumes (*Sax 1979). Hydrolyzes in presence of water forming benzoic and
hydrochloric acids (Hawley 1981, p. 119; *Merck 1983).
Hazardous Decomposition or Byproducts: Produces toxic and corrosive fumes
when it reacts with water or steam (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Synthetic dyes; organic synthesis (Hawley 1981, p. 119).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Material is extremely hazardous to health but areas may be entered with
extreme care. No skin surface should be exposed (*NFPA 1978).
Spilled material should not be touched. Take up spills with
noncombustible absorbent material. For large spills dike far ahead of
spill for later disposal (DOT 1984, Guide 60). Water should be used in
copious amounts because of reaction with water and formation of toxic
by-products (see Section IV above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Highly irritating to skin and mucous
membranes (*Merck 1983).
-------
CAS Registry Number: 98-07-7
Page 4 of 4
BENZOTRICHLORIDE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. In case of contact with material, immediately
flush skin or eyes with copious amounts of running water for at least 15
minutes. Remove and isolate contaminated clothing and shoes at the site.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
60).
-------
CAS Registry Number: 98-13-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRICHLOROPHENYLSILANE
CAS Registry Number: 98-13-5
Synonyms: Silane, Trichlorophenyl-; Phenyltrichlorosilane; Phenyl
Trichlorosilane; Phenylsilicon Trichloride; Phenyltrichlorosilicane; Silane,
Phenyltrichloro-; Silicon Phenyl Trichloride
Chemical Formula: C6H5Cl3Si
Molecular Weight: 211.55
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.0003 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 395°F, 201.5°C (*Weast 1979)
Specific Gravity (H2O=1): 1.326 at 18°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 7.36 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (*Weast 1979)
Appearance and Odor: Colorless liquid (*Weast 1979)
-------
CAS Registry Number: 98-13-5
Page 2 of 4
TRICHLOROPHENYLSILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2631)
Skin: Yes (Sax 1984, p. 2631)
Ingestion: Yes (Sax 1984, p. 2631)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic; may cause
death or permanent injury after short inhalation exposure to small quantity
(*Sax 1975). Chemical burns to all exposed membranes and tissues with
severe tissue destruction. Inhalation -- lungs may fill up with fluid or
throat may swell causing suffocation. Eyes — damage to corneas may cause
blindness. Delayed: after oral exposure stomach and intestines may
perforate or be obstructed by scar tissue (*Rumack 1975 to Present,
Gosselin 1984, pp. III-10-11).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 196°F (OC) (*Sax 1979)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Dry chemical, carbon dioxide, fog, or foam. May
react violently with water (DOT 1984, Guide 29).
Special Fire Fighting Procedures: Full protective clothing, including
self-contained breathing apparatus, coat, pants, gloves, boots, and bands
around legs, arms, and waist should be provided. No skin surface should be
exposed (*NFPA 1978). Move container from fire area if you can do so
without risk. Cool containers that are exposed to flames with water from
the side until well after fire is out. Withdraw immediately in case of
rising sound from venting safety device or any discoloration of tank due to
fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: Do not get water inside containers.
Vapors may travel to ignition source and flash back. Runoff to sewer may
create fire or explosion hazard. Flammable/combustible material; may be
ignited by heat, sparks or flames. Container may explode in heat of fire.
Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may
create fire or explosion hazard (DOT 1984, Guide 29).
NFPA Flammability Rating: 2
-------
CAS Registry Number: 98-13-5
Page 3 of 4
TRICHLOROPHENYLSILANE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes ("Hawley 1977)
Stable:
Conditions to Avoid: Readily hydrolyzed in water/moisture, producing
hydrochloric acid (*Hawley 1977). Avoid mixing with water or exposing
to moisture (*Sax 1979).
Incompatibility (Materials to Avoid): Do not mix with halogenated
compounds, because a trace quantity of free halogen may cause violent
explosion (*Bretherick 1979). May react violently with water (DOT 1984,
Guide 29).
Hazardous Decomposition or Byproducts: Emits toxic chloride fumes when
heated to decomposition (Sax 1984, p. 2631).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Monomer for copolymers in water repellants, in electrical insulating
resins, in high temperature resins for paints (*SRI). Intermediate for
silicones (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
No skin surface should be exposed (see Section III above). Isolate hazard
area. Stay upwind; keep out of low areas. Shut off ignition sources; no
flares, smoking, or flames in hazard area. Do not touch spilled material;
stop leak if you can do it without risk. Do not get water inside
container. Take up small spills with sand or other noncombustible
absorbent material and place into containers for later disposal. Dike far
ahead of large spills for later disposal (DOT 1984, Guide 29).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation — severe difficulty in
breathing, chest pains. Eye contact -- severe pain, swelling, cornea
-------
CAS Registry Number: 98-13-5
Page 4 of 4
TRICHLOROPHENYLSILANE
SECTION IX (continued)
damage. Skin contact severe burns and pain. Ingestion — mild to
moderately severe oral and esophageal burns, with severe burns occurring in
stomach. Perforations and peritonitis may occur. Severe irritation may
produce spontaneous vomiting. Viscid white or blood-stained foamy mucus
and threads of tissue may appear in mouth (*Rumack 1975 to Present).
Emergency and First Aid Procedures: Move victim to fresh air. If not
breathing, perform artifical respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least IS minutes. Keep victim quiet and maintain
normal body temperature (DOT 1984, Guide 29). In case of oral exposure, do
not induce vomiting. Have patient drink 1-2 large glasses of water or milk
to dilute stomach contents, then give demulcents such as milk, cornstarch,
and water (*Rumack 1975 to Present).
-------
CAS Registry Number: 98-16-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BENZENAMINE, S-(TRIFLUOROMETHYL)-
CAS Registry Number: 98-16-8
Synonyms: m-(Trifluoromethyl)aniline; 1 -Amino-3-(Trifluoromethyl)Benzene;
3-(Trifluoromethyl)Aniline; 3-(Trifluoromethyl)Benzenamine; 3-Aminobenzo-
trifluoride; alpha,alpha,alpha-Trifluoro-m-Toluidine; m-Amino-alpha,alpha,
alpha-Trifluorotoluene; m-Aminobenzotrifluoride; ra-Toluidine,
alpha,alpha,alpha-Trifluoro-; Toluene, 3-Amino-alpha,alpha,alpha-Trifluoro-
Chemical Formula: C7H6F3N
Molecular Weight: 161.13
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.44 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 369.5°F, 187.5°C at 764 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.303 at 15.5°C (Sax 1984, p. 192)
Vapor Pressure (mmHg): Not Found
Melting Point: 37°F, 3°C (Sax 1984, p. 192)
Vapor Density (AIR=1): 5.56 (Sax 1984, p. 192)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (*Weast 1979)
-------
CAS Registry Number: 98-16-8
Page 2 of 4
BENZENAMINE, 3-(TRIFLUOROMETHYL)-
SECTION II (continued)
Appearance and Odor: Colorless to yellow oily liquid (*Hawley 1977) with
aniline-like odor (Sax 1984, p. 192).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 192)
Skin: Yes (DOT 1984, Guide 55)
Ingestion: Yes (Sax 1984, p. 192)
Health Hazards (Acute, Delayed, and Chronic): Contact may cause burns to
skin and eyes. May be poisonous if inhaled, swallowed or absorbed through
the skin (DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
-UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Move container from fire area
if you can do so without risk. Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. Cylinder may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 98-16-8
Page 3 of 4
BENZENAMINE, 3-(TRIFLUOROMETHYL)-
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluorides and nitrogen oxides (Sax 1984, p. 192).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as a chemical intermediate for herbicides,
antihypertensives, and diuretics (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. If water
pollution occurs, notify appropriate authorities. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other non-combustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 98-16-8
Page 4 of 4
BENZENAMINE, 3-(TRIFLUOROMETHYL)-
COMMENTS:
Sources searched but no information found:
ACGIH 1984
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health & Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 98-87-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BENZAL CHLORIDE
CAS Registry Number: 98-87-3
Synonyms: (Dichloromethyl)Benzene; alpha,alpha-Dichlorotoluene; Benzene,
(Dichloromethyl)-; Benzyl Dichloride; Benzylene Chloride; Benzylidene Chloride;
Chlorobenzal; Dichlorophenylmethane; Toluene, alpha,alpha-Dichloro-
Chemical Formula: C7H6C12
Molecular Weight: 161.03
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.4 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 5,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 401°F, 205°C (*Merck 1983)
Specific Gravity (H2O=1): 1.26 (*Merck 1983)
Vapor Pressure (mmHg): 1 at 35.4°C (Weast 1979, p. D-209)
Melting Point: 2.48°F, -16.4°C (Weast 1979, p. C-523)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Merck 1983)
Appearance and Odor: Colorless oily liquid with a faint aromatic odor
(*Hawley 1981) or pungent odor (*Merck 1983)
-------
CAS Registry Number: 98-87-3
Page 2 of 3
BENZAL CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): Acute: vapors are highly
irritating to eyes (*Grant 1974). May be fatal if inhaled, swallowed, or
absorbed through skin (*DOT 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: This material'may burn but will not ignite easily (*DOT
1984).
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires: dry chemical, carbon dioxide,
water spray, or foam. For large fires: water spray, fog, or foam. Move
container from fire area if possible. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(*DOT 1984).
Special Fire Fighting Procedures: Keep unnecessary people away and
isolate hazard area. Stay upwind and keep out of low areas. Wear positive
pressure breathing apparatus and special protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases. Runoff from fire control water may give off poisonous
gases and may cause pollution. Cylinder may explode in the heat of fire
(*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 98-87-3
Page 3 of 3
BENZAL CHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Reacts with water to release
hydrochloric acid (*Grant 1974).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in dyes and in the manufacture of benzaldehyde and cinnamic acid
(*Hawley 1981).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapors. Avoid ingestion and skin contact (see Section III
above). For spills or leaks, do not touch material. Stop leak if
possible. Use water spray to reduce vapors. For small spills, take up
with sand or other noncombustible material and place in containers for
later disposal. For small dry spills, place material in clean dry container
with shovel and move containers from spill area. For large spills,
dike far ahead of spills for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Eye irritation occurs upon exposure
(*Grant 1974).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If not breathing give artificial respiration; if
breathing is difficult give oxygen. In case of contact, immediately flush
skin or eyes with water for at least 15 minutes. Speedy removal from skin
is essential. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Keep a
careful watch since effects may be delayed (*DOT 1984).
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CAS Registry Number: 98-95-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NITROBENZENE
CAS Registry Number: 98-95-3
Synonyms: Benzene, Nitro-; Essence of Mirbane; Essence of Myrbane; Mirbane
Oil; NCI-C60082; Nitrobenzol; Oil of Mirbane; Oil of Myrbane
Chemical Formula: C6H5NO2
Molecular Weight: 123.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 10,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 411.4°F, 210.8°C (*Weast 1979)
Specific Gravity (H2O=1): 1.2037 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): 1 at 44.4°C (*Sax 1979)
Melting Point: 42°F, 5.7°C (*Weast 1979)
Vapor Density (AIR=1): 4.3 (NFPA 1984, p. 325M-74)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in about 500 parts water (*Merck 1976)
Appearance and Odor: Greenish-yellow crystals or yellow, oily liquid
(*Hawley 1977) with an odor of volatile oil almond (*Merck 1976).
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CAS Registry Number: 98-95-3
Page 2 of 4
NITROBENZENE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 1 ppm (5 mg/m8) (NIOSH 1987, p. 174)
ACGIH TLV: TWA 1 ppm (5 mg/ms) (skin) (ACGIH 1986-87, p.25)
IDLH: 200 ppm (NIOSH/OSHA 1978, p. 140)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Gosselin 1976)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Can cause death due to
respiratory failure (*Arena 1974). Classified as extremely toxic. The
mean lethal oral dose is probably between 1 and 5 grams. Systemic effects
may be delayed for a few hours (Gosselin 1984, p. 11-214). This compound
is rapidly absorbed through the skin (Merck 1983, p. 945). It is a
powerful methemoglobin former (*Patty 1963).
Medical Conditions Generally Aggravated by Exposure: Ethyl alcohol
aggravates intoxication caused by nitrobenzene exposure (Gosselin 1984, p.
11-214).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 88°C (CC) (*Sunshine 1969)
Flammable Limits:
LEL: 1.8% (*Encyc Occupat Health and Safety 1971)
UEL: Not Found
Extinguishing Methods: Use water spray, dry chemical, foam, or carbon
dioxide (NFPA 1984, pp. 49-67).
Special Fire Fighting Procedures: Move container from fire area if you
can do it without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Wear
positive pressure breathing apparatus and special protective clothing.
Remove and isolate contaminated clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Moderate explosion hazard when
exposed to heat or flame. Reacts violently with nitric acid, aluminum
trichloride plus phenol, aniline plus glycerine, silver perchlorate and
nitrogen tetroxide (Sax 1984, p. 2010).
NFPA Flammability Rating: 2
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CAS Registry Number: 98-95-3
Page 3 of 4
NITROBENZENE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Sunlight (*Sax 1975), physical damage to
container, freezing, and intense heat (NFPA 1984, pp. 49-67).
Incompatibility (Materials to Avoid): Aluminum trichloride; aniline;
gycerol; sulfuric acid; oxidants; phosphorus pentachloride; potassium;
potassium hydroxide (Sax 1984, p. 2010)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a solvent for cellulose ethers; modifying esterification of
cellulose acetate; ingredient of metal polishes (*Hawley 1977), in soaps
and shoe polishes; for refining lubricating oils; manufacturing of
pyroxylin compound (*Merck 1976); a preservative in spray paints;
constituent of floor polishes; substitute for almond essence; in perfume
industry (*Browning 1965); chemical intermediate for aniline and
dichloroanilines (*SRI). Registered as an insecticide for use on cadavers
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors (DOT 1984, Guide 55). Absorb spilled materials in
vermiculite, dry sand, earth, or similar material, and place in sealed
containers for disposal in secured sanitary landfill (*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 98-95-3
Page 4 of 4
NITROBENZENE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
CPE GOOD/LIMITED
Neoprene POOR/MANY
Nitrile POOR/MANY
PVC POOR/LIMITED*
Teflon GOOD/LIMITED
Viton EXCELLENT/MANY
Viton/Chlorobutyl GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 98-95-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
NITROBENZENE
(98-95-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Greenish-yellow crystals or yellow, oily liquid.
Odor - Almondlike.
Uses - Solvent for metal, shoe, and floor polishes; lubricating oils, spray
paints, soaps, perfumes, insecticides, chemical intermediate.
Other Names - Mirbane oil, nitrobenzol.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, 1% methylene blue.
Signs and Symptoms of Acute Nitrobenzene Exposure:
Warning: Effects may be delayed. Caution is advised. Prior alcohol
consumption aggravates the effects of nitrobenzene poisoning.
Note: Absorption of nitrobenzene through the skin is rapid.
Signs and symptoms of acute exposure to nitrobenzene may be severe and include
cyanosis (blue tint to the skin and mucous membranes), tachycardia (rapid heart
rate), hypotension (low blood pressure), and cardiac arrhythmias. Respiratory
depression and respiratory failure may also occur. Headache, lethargy,
weakness, vertigo (dizziness), severe depression, and coma may be noted.
Gastrointestinal symptoms include nausea and vomiting. Urine and vomitus may
have the odor of bitter almonds.
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EFATG
CAS Registry Number: 98-95-3
Page 2 of 3
NITROBENZENE
Emergency Life-Support Procedures:
Acute exposure to nitrobenzene may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to nitrobenzene.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to nitrobenzene.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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EFATG
CAS Registry Number: 98-95-3
Page 3 of 3
NITROBENZENE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of nitrobenzene is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of nitrobenzene may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 99-98-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIMETHYL-p-PHENYLENEDIAMINE
CAS Registry Number: 99-98-9
Synonyms: N,N-Dimethyl-p-Benzenediamine; 1,4-Benzenediamine, N,N-Dimethyl-;
4-(Dimethylamino)Aniline; 4-Amino-N,N-Dimethylaniline; CI 76075;
Dimethyl-para-Phenylenediamine; Dimethyl-paraphenylenediamine; DMPD;
N,N-Dimethyl-1,4-Benzenediamine; N,N-Dimethyl-l,4-Phenylenediamine;
N,N-Dimethyl-p-Phenylenediamine; p-(Dimethylamino)Aniline; p-Amino-N,N-
Dimethylaniline; p-Aminodimethylaniline; p-Dimethylaminophenylamine;
p-Phenylenediamine, N,N-Dimethyl-
Chemical Formula: C8H12N2
Molecular Weight: 136.22
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(guinea pig) 0.0013 mg/liter (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 504°F, 262°C (*Merck 1976)
Specific Gravity (H2O=1): 1.036 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 127°F, 53°C (*Merck 1976); also stated as 106°F, 41°C
(Merck 1983, p. 474)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 99-98-9
Page 2 of 4
DIMETHYL-p-PHENYLENEDIAMINE
SECTION II (continued)
Solubility in Water: Soluble (*Merck 1976)
Appearance and Odor: Colorless to reddish-violet solid (*Hawley 1977,
*Merck 1976)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (Sax 1984, p. 1190)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): Lowest toxic dose with skin
effect is 14 mg/kg (*NIOSH/RTECS 1985). Irritant to skin and eyes (*Hawley
1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1190).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Hawley 1977)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 99-98-9
Page 3 of 4
DIMETHYL-p-PHENYLENEDIAMINE
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1190).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Used in the production of methylene blue and photodeveloper. It is a
reagent for hydrogen sulfide, cellulose, organic synthesis (*Hawley 1977).
Chemical intermediate for dyes and diazonium chloride salts; analytical
reagent for chlproamine detection in water (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Nonspecific -- Phenylenediamine). Do not touch material; stop leak if it
can be done without risk. Keep unnecessary people away. Isolate area and
deny entry. Stay upwind and out of low areas. For small spills, use shovel
to place material into clean, dry container and cover; move containers from
spill area. For large spills, dike far ahead to collect for later
disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Nitrile POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
-------
CAS Registry Number: 99-98-9
Page 4 of 4
DIMETHYL-p-PHENYLENEDIAMINE
SECTION IX (continued)
Emergency and First Aid Procedures: Treatment is as for general
poisoning. Seek medical attention. Establish respiration. Prevent
absorption. Induce vomiting. In case of skin contamination decontaminate
with water and soap. In case of eye exposure, flush thoroughly with water
(*Rumack 1975 to Present).
-------
CAS Registry Number: 100-14-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - BENZENE, l-(CHLOROMETHYL)-4-NITRO-
CAS Registry Number: 100-14-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, page 771): p-Nitrobenzyl
Chloride; Toluene, alpha-Chloro-p-Nitro-; alpha-Chloro-p-Nitrotoluene
Chemical Formula: C7H6C1NO2
Molecular Weight: 171.59
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(rat) 0.28 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 159.8°F, 71°C (Weast 1979, p. C-522)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. C-522)
Appearance and Odor: Not Found
-------
CAS Registry Number: 100-14-1
Page 2 of 4
BENZENE, l-(CHLOROMETHYL)-4-NITRO-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 748)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 748)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific —
Chloronitrotoluene) Poisonous if swallowed or dust is inhaled (DOT 1984,
Guide 53).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Chloronitrotoluene) This
material may burn but does not ignite readily. Small fires: dry chemical,
carbon dioxide, water spray or foam. Large fires: Water spray, fog or
foam. Move container from fire area if you can do it without risk
(DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Chloronitrotoluene)
Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive
pressure if available) breathing apparatus and full protective clothing
(DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Incompatible with sodium hydroxide
(Sax 1984, p. 748).
-------
CAS Registry Number: 100-14-1
Page 3 of 4
BENZENE, l-(CHLOROMETHYL)-4-NITRO-
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Chloronitrotoluene)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. If water pollution occurs, notify
appropriate authorities. Do not touch spilled material; stop leak if you
can do so without risk. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel, place material into
clean, dry container and cover; move containers from spill area.
Large spills: dike far ahead of spill for alter disposal (DOT 1984,
Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
CPE GOOD/LIMITED**
Nitrile POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
-------
CAS Registry Number: 100-14-1
Page 4 of 4
BENZENE, l-(CHLOROMETHYL)-4-NITRO-
SECTION IX - EMERGENCY TREATMENT INFORMATION (continued)
Emergency and First Aid Procedures: (Non-Specific -- Chloronitrotoluene)
Move victim to fresh air; call emergency medical care. Remove and isolate
contaminated clothing and shoes at the site. In case of contact with
material, immediately flush skin and eyes with running water for at least
15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
Hawley 1981
Merck 1983
Student 1981
Weiss 1980
Doull 1980
Clayton and Clayton 1981-82
Gosselin 1984
Encyc Occupat Health and Safety 1983
-------
CAS Registry Number: 100-44-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - BENZYL CHLORIDE
CAS Registry Number: 100-44-7
Synonyms: (Chloromethyl)Benzene; alpha-Chlorotoluene; Benzene,
(Chloromethyl)-; Chloromethylbenzene; Chlorophenylmethane; NCI-CO6360;
omega-Chlorotoluene; Toluene, alpha-Chloro-; Tolyl Chloride
Chemical Formula: C7H7C1
Molecular Weight: 126.58
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.416 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds) (statutory); 100 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 354°F, 179°C (*Merck 1983)
Specific Gravity (H2O=1): 1.100 at 20°C/20°C (*Merck 1983)
Vapor Pressure (mmHg): 1 at 22°C (*IARC 1985)
Melting Point: -45 to -54°F, -43 to -48°C (*Merck 1983)
Vapor Density (AIR=1): 4.4 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Merck 1983)
Appearance and Odor: Colorless to slightly yellow liquid (*NFPA 1978);
irritating odor (*Merck 1983)
-------
CAS Registry Number: 100-44-7
Page 2 of 4
BENZYL CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 ppm (5 mg/m3) (OSHA 1984, p. 661)
ACGIH TLV: TWA Ippm (5 mg/ms) (ACGIH 1986-87, p.10)
IDLH: 10 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Occupational exposure recommended standard —
air: ceiling concentration 5 mg/ms/15 minutes (*NIOSH/RTECS 1985)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Intensely irritating to
skin, eyes, and mucous membranes (*Merck 1983). Highly toxic; may cause
death or permanent injury after very short exposure to small quantities
(*Sax 1975). Has been listed as a direct-acting or primary carcinogen
(*Doull 1980). Large doses cause central nervous system depression (*Merck
1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 153°F, 67°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: 1.1% (*NFPA 1978)
UEL: Not Found
Extinguishing Methods: Use water spray, dry chemical, foam, or carbon
dioxide (*NFPA 1978). Use water to keep fire-exposed containers cool
(*NFPA 1978).
Special Fire Fighting Procedures: Areas may be entered freely with
full-faced mask, self-contained breathing apparatus which provides eye
protection, rubber gloves, and hand and arm protection (*NFPA 1978).
Unusual Fire and Explosion Hazards: It burns but does not ignite readily.
It may ignite combustibles (DOT 1984, Guide 59).
NFPA Flammability Rating: 2
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Keep separate from oxidizing materials (*Sax
1979). May become unstable at elevated temperatures and pressures; may
react with water resulting in some nonviolent release of energy (*NFPA
1978).
-------
CAS Registry Number: 100-44-7
Page 3 of 4
BENZYL CHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Incompatible with active metals
such as copper, aluminum, magnesium, iron, zinc, and tin and keep from
strong oxidizing agents (NIOSH/OSHA 1978, p. 50). Avoid acids or acid
fumes (*Sax 1979).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic and corrosive fumes. Some organic chlorides decompose to yield
phosgene (*Sax 1978).
Hazardous Polymerization: May Occur: Yes (*CHRIS 1978)
May Not Occur:
Conditions to Avoid: Polymerizes with evolution of heat and hydrogen
chloride when in contact with all common metals except nickel and lead
(*CHRIS 1978).
SECTION VI - USE INFORMATION
It is used in the manufacturing of perfumes, pharmaceutical products, dyes,
synthetic tannins, artificial resins, (*Merck 1983) photographic developer,
gasoline gum inhibitors, penicillin precursors (*Hawley 1981). Also,
benzyl chloride is used as an intermediate in the manufacture of other
organic chemicals (*SRI). In the past, it was used as an irritant gas in
chemical warfare (*IARC 1972-1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
If leak or spill has not ignited, use water spray to disperse vapors and to
provide protection for persons attempting to stop leak. Use water spray to
flush spills away from exposures (*NFPA 1978). Take up small spills with
sand or other noncombustible absorbent material and place into containers
for later disposal. For larger spills, dike for later disposal (DOT 1984,
Guide 59).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 100-44-7
Page 4 of 4
BENZYL CHLORIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene POOR/LIMITED*
CPE POOR/LIMITED*
Neoprene POOR/LIMITED*
Nitrile GOOD/LIMITED*
PVC POOR/LIMITED*
Teflon GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 100-44-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
BENZYL CHLORIDE
(100-44-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to slightly yellow liquid.
Odor - Irritating, pungent.
Commercial Form - Liquid in 475-pound nickel drums, 100-pound carboys, tank
trucks, tank cars.
Uses - Manufacture of perfumes, Pharmaceuticals, dyes, synthetic tannins,
artificial resins, and gasoline gum inhibitors; photographic developer;
chemical warfare agent.
Materials to Avoid - Water (except for use in emergency life support).
Caution: Benzyl chloride may liberate toxic gas upon decomposition. Contact
with water may result in the formation of hydrogen chloride gas.
Other Names - Alpha-chlorotoluene, (chloromethyl)benzene, chlorophenylmethane,
omega-chlorotoluene, tolyl chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Benzyl Chloride Exposure:
Benzyl chloride may be very irritating to the skin, eyes, and mucous
membranes. Eye irritation may be severe, and permanent eye damage may result.
Lacrimation (tearing) is common. Other signs and symptoms of acute exposure
may include headache, dizziness, weakness, fatigue, irritability, itching of
the skin, profuse sweating, insomnia, tremors, unsteadiness, and central
nervous system depression. Gastrointestinal effects may include nausea,
vomiting, cramps, anorexia, and diarrhea. Pulmonary edema and disturbance of
liver function may also occur.
-------
EFATG
CAS Registry Number: 100-44-7
Page 2 of 3
BENZYL CHLORIDE
Emergency Life-Support Procedures:
Acute exposure to benzyl chloride may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to benzyl chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to benzyl chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 100-44-7
Page 3 of 3
BENZYL CHLORIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 102-36-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ISOCYANIC ACID, 3,4-DICHLOROPHENYL ESTER
CAS Registry Number: 102-36-3
Synonyms: 3,4-Dichlorophenyl Isocyanate; Benzene, l,2-Dichloro-4-Isocyanato-
Chemical Formula: C7HSC12NO
Molecular Weight: 188.01
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
t
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(mouse) 0.14 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II — PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 244°F, 118°C at 18 mmHg (Beilstein 1954, Vol. 12/3, p.
1405)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 113°F, 45°C (Beilstein 1954, Vol. 12/3, p. 1405)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: White to yellow solid (*Hawley 1977)
-------
CAS Registry Number: 102-36-3
Page 2 of 3
ISOCYANIC ACID, 3,4-DICHLOROPHENYL ESTER
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (DOT 1984, Guide 53)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Strong irritant to tissue,
especially eyes and mucous membranes (*Hawley 1977)
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam. Move container from fire area if you can do so
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: Inhalation of dust poisonous; fire
may produce irritating or poisonous gases (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
-------
CAS Registry Number: 102-36-3
Page 3 of 3
ISOCYANIC ACID, 3,4-DICHLOROPHENYL ESTER
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Chemical intermediate; organic synthesis (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation of dust (see Section III above). Do not touch spilled
material; stop leak if you can do so without risk. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes (DOT 1984, Guide 53).
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CAS Registry Number: 103-85-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENYLTHIOUREA
CAS Registry Number: 103-85-5
Synonyms: Urea, l-Phenyl-2-Thio-; l-Phenyl-2-Thiourea; 1-Phenylthiourea;
alpha-Phenylthiourea; N-Phenylthiourea; NCI-C02017; Phenylthiocarbamide; PTC;
PTU; Thiourea, Phenyl-; U6324; USAF EK-1569
Chemical Formula: C7H8N2S
Molecular Weight: 152.22 (*Merck 1983)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.3 (*Merck 1983)
Vapor Pressure (mmHg): Not Found
Melting Point: 148°C (Aldrich 1986, p.1083)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 400 parts cold water; 17 parts boiling
water (*Merck 1983).
Appearance and Odor: Needle-like crystals (Sax 1984, p. 2205).
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CAS Registry Number: 103-85-5
Page 2 of 3
PHENYLTHIOUREA
SECTION HI - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (Sax 1984, p. 2205)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely toxic. The probable oral lethal dose is 5-50 mg/kg or between 7
drops and 1 teaspoon for a 70 kg (150 Ib.) person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Dangerous disaster hazard; emits
toxic fumes of oxides of sulfur and nitrogen when heated to decomposition
(Sax 1984, p. 2205).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Acid or acid fumes (Sax 1984,
p. 2205)
Hazardous Decomposition or Byproducts: When heated to decomposition, or
on contact with acid or acid fumes it emits highly toxic fumes of sulfur
oxides and nitrogen oxides (Sax 1984, p. 2205).
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CAS Registry Number: 103-85-5
Page 3 of 3
PHENYLTHIOUREA
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacture of rodenticides (*Gosselin 1976) and in medical
genetics (Merck 1983, p. 1794).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation or contact with skin (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may result in vomiting,
difficult breathing, noisy breathing, cyanosis, and low body temperature
(*Gosselin 1976).
Emergency and First Aid Procedures: Phenylthiourea is similar to Antu
(Gosselin 1984, p. H-350). Dermal exposure: wash exposed area twice with
soap and water. Eye exposure: wash copiously with water for 15 minutes.
Inhalation: remove to fresh air (*Rumack 1975 to Present). Oral: Induce
vomiting (Gosselin 1984, p. 111-41).
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CAS Registry Number: 106-89-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - EPICHLOROHYDRIN
CAS Registry Number: 106-89-8
Synonyms: (Chloromethyl)Ethylene Oxide; (DL)-alpha-Epichlorohydrin;
l,2-Epoxy-3-Chloropropane; l-Chloro-2,3-Epoxy propane; 2,3-Epoxypropyl Chloride;
3-Chloro-l,2-Epoxypropane; 3-Chloro-l,2-Propylene Oxide; Alpha-Epichlorohydrin;
Chloromethyloxirane; Chloropropylene Oxide; ECH; Epichlorophydrin;
Epichlorhydrin; gamma-Chloropropylene Oxide; Glycerol Epichlorhydrin; Glycerol
Epichlorohydrin; Glycidyl Chloride; NCI-CO7001; Oxirane, (Chloromethyl)-;
Oxirane, 2-(Chloromethyl); SKEKHG
Chemical Formula: C3H5C1O
Molecular Weight: 92.53
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 1,000 (pounds) (statutory); 100 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 241.7°F, 116.5°C (*Weast 1979)
Specific Gravity (H2O=1): 1.801 at 20°C/4°C (*Weast 1979); 1.18 at 20°C
(Merck 1983, p. 520)
Vapor Pressure (mmHg): 10 at 16.6°C (*Sax 1975)
Melting Point: -54.4°F, -48°C (*Weast 1979); -14.1°F, -25.6°C (Merck
1983, p. 520)
Vapor Density (AIR=1): 3.29 (*Sax 1975)
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CAS Registry Number: 106-89-8
Page 2 of 4
EPICHLOROHYDRIN
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Merck 1976)
Appearance and Odor: Colorless liquid (*Sax 1975) with a pungent, garlic,
sweet odor (*CHRIS 1978).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 ppm (19 mg/ms) (NIOSH 1987 p.114)
ACGIH TLV: TWA 2 ppm (10 mg/m3) (to be changed) (skin) (ACGIH 1986-87,
P.18)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 92)
Other Limits Recommended: NIOSH: Lowest feasible limit; potential
occupational carcinogen (NIOSH 1987, p. 114)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): This compound is caustic as
both a liquid and gas. Irritation of the eyes and skin, and skin
sensitization has been observed (*LeFaux 1968; *Sax 1975). Exposure to
epichlorohydrin has caused inflammation of the lungs, asthmatic bronchitis,
and liver and kidney damage (*Gosselin 1976; *Sax 1975). In acute
poisonings, death may be caused by respiratory paralysis (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 93°F(CC) (*ACGIH 1980); 105°F(OC) (*Merck
1983)
Flammable Limits:
LEL: 3.8% (*NFPA 1978)
UEL: 21.0% (*NFPA 1978)
Extinguishing Methods: Use water spray, dry chemical, foam or carbon
dioxide. Water spray may be used to dilute spills to non-flammable
mixtures. If leak or spill has not ignited, use water spray to disperse
the vapors. Keep fire-exposed containers cooled with water (*NFPA 1978).
Special Fire Fighting Procedures: If fire becomes uncontrollable, or
containers are exposed to direct flames, evacuate for a radius of 1,500
feet (*Student 1981). Isolate for one-half mile in all directions if tank
car or truck is involved in fire (DOT 1984, Guide 30). Epichlorohydrin may
react violently with water (*NFPA 1978).
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CAS Registry Number: 106-89-8
Page 3 of 4
EPICHLOROHYDRIN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, this
compound evolves highly toxic fumes of phosgene (*Sax 1975) and carbon
monoxide (*General Electric Co. MSDS #335B 1979).
NFPA Flammability Rating: 2
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Heat and contaminants (*NFPA 1978).
Incompatibility (Materials to Avoid): Reactive and incompatible with
strong oxidizers, strong acids, caustics, zinc, aluminum, chlorides of iron
and aluminum (NIOSH/OSHA 1978, p. 92), and compounds with an active
hydrogen atom, including water (*ITI 1982).
Hazardous Decomposition or Byproducts: When heated, can evolve fumes of
phosgene (*Sax 1975) and carbon monoxide (*General Electric Co. MSDS #335B
1979).
Hazardous Polymerization: May Occur: Yes (*CHRIS 1978)
May Not Occur:
Conditions to Avoid: Strong acids and bases (*CHRIS 1978); certain
curing agents such as ethylenediamine (*General Electric Co. 1979, MSDS
#335B).
SECTION VI -- USE INFORMATION
Insect fumigant, solvent (*Merck 1976), raw material or intermediate for
chemical synthesis, cross-linking agent, heat stabilizer for plastics,
comonomer for epoxy resins (*SRI), papermaking additive (*Kirk-Othmer
1978). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Shut off ignition sources; no flares,
smoking or flames in hazard area. Do not touch spilled material; stop leak
if you can do it without risk. Use water spray to reduce vapors; do not
get water inside container. Small spills: flush area with flooding
amounts of water. Large spills: dike far ahead of spill for later
disposal (DOT 1984, Guide 30).
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CAS Registry Number: 106-89-8
Page 4 of 4
EPICHLOROHYDRIN
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
CPE POOR/LIMITED*
Neoprene POOR/LIMITED
Nitrile POOR/LIMITED
PE POOR/MANY
PVC POOR/LIMITED
Saranex POOR/LIMITED
Teflon EXCELLENT/MANY
Viton POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 106-89-8
Page I of 3
Emergency First Aid Treatment Guide
for
EPICHLOROHYDRIN
(106-89-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Pungent, sweet, or chloroformlike.
Commercial Form - Liquid shipped in drums or tank cars.
Uses - Manufacture of glycerol, epoxy resins, and pesticides; cross-linking
agent and heat stabilizer for plastics; stabilizer in chlorine-containing
materials; chemical synthesis; solvent.
Materials to Avoid - Oxidizers, acids, caustic substances, water (except for
use in emergency life support).
Other Names - l-Chloro-2,3-epoxypropane, chloromethyloxirane, glycerol
epichlorohydrin, glycidyl chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
dopamine, norepinephrine, furosemide.
Signs and Symptoms of Acute Epichlorohydrin Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
Acute exposure to epichlorohydrin may result in nausea, vomiting, and abdominal
pain. Liver and kidney effects may be observed. The respiratory tract may
become irritated, dyspnea (shortness of breath) may occur, and in acute cases,
respiratory paralysis has been observed. Central nervous system and
respiratory depression have been noted. Facial swelling, mucosal irritation,
dermatitis (red, inflamed skin), and eye irritation may also occur following
exposure to epichlorohydrin.
-------
EFATG
CAS Registry Number: 106-89-8
Page 2 of 3
EPICHLOROHYDRIN
Emergency Life-Support Procedures:
Acute exposure to epichlorohydrin may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to epichlorohydrin.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to epichlorohydrin.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. Jf eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 106-89-8
Page 3 of 3
EPICHLOROHYDRIN
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of epichlorohydrin is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 106-96-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPARGYL BROMIDE
CAS Registry Number: 106-96-7
Synonyms: Propyne, 3-Bromo-; gamma-Bromoallylene; 3-Bromopropyne;
3-Bromo-1 -propy ne
Chemical Formula: CsH3Br
Molecular Weight: 118.97
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(guinea pig) 0.029 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 190-194°F, 88-90°C (Sax 1984, p. 2295)
Specific Gravity (H2O=1): 1.564-1.570 (Sax 1984, p. 2295)
Vapor Pressure (mmHg): Not Found
Melting Point: -77.9°F, -61.07°C (Sax 1984, p. 2295)
Vapor Density (AIR=1): 4.10 (NFPA 1984, p. 325u-81)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless liquid, sharp odor (Sax 1984, p. 2295)
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CAS Registry Number: 106-96-7
Page 2 of 3
PROPARGYL BROMIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (Sax 1984, p. 2295)
Health Hazards (Acute, Delayed, and Chronic): This material is very toxic
via the oral route (Sax 1984, p. 2295). If inhaled, may be harmful;
contact may cause burns to skin and eyes (DOT 1984, Guide 29).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 50°F, 10°C (NFPA 1984, p. 325u-81)
Flammable Limits:
LEL: 3.0% (*NFPA 1978)
UEL: Not Found
Extinguishing Methods: Use water, foam, carbon dioxide, or dry chemical
(Sax 1984, p. 2295)
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing. Move container from fire area if you can do
it without risk. Do not get water inside container. Cool containers that
are exposed to flames with water from the side until well after fire is
out. Withdraw immediately in case of rising sound from venting safety
device or any discoloration of tank due to fire. Isolate for 1/2 mile in
all directions if tank car or truck is involved in fire (DOT 1984, Guide
29).
Unusual Fire and Explosion Hazards: This material detonates at 428°F,
220PC or more; ignites by impact. Emits highly toxic fumes of bromides
when heated to decomposition (Sax 1984, p. 2295).
NFPA Flammability Rating: 3
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Yes (Sax 1984, p. 2295)
Stable:
Conditions to Avoid: Heat, flame, shock, and other chemicals (Sax
1984, p. 2295)
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CAS Registry Number: 106-96-7
Page 3 of 3
PROPARGYL BROMIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Reacts vigorously with oxidizing
materials. Becomes shock-sensitive when mixed with chloropicrin (Sax 1984,
p. 2295).
Hazardous Decomposition or Byproducts: Highly toxic fumes of bromine
containing compounds are formed when this material is heated to
decomposition (Sax 1984, p. 2295).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as a soil fumigant (Hawley 1981, p. 861). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no flames, smoking or flames in hazard area. Do
not touch spilled material; stop leak if you can do it without risk. Use
water spray to reduce vapors, do not get water inside container. Take up
spills with sand or noncombustible absorbent material. For large spills
dike far ahead (DOT 1984, Guide 29).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include skin irritation and
tearing of the eyes (*NFPA 1978).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
29).
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CAS Registry Number: 107-02-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ ACROLEIN
CAS Registry Number: 107-02-8
Synonyms: Acraldehyde; Acrylaldehyde; Acrylic Aldehyde; Allyl Aldehyde;
Aqualin; Aqualine; Ethylene Aldehyde; Magnacide H; NSC 8819; Propenal;
2-Propenal; Prop-2-en-l-al; 2-Propen-l-one
Chemical Formula: CSH4O
Molecular Weight: 56.06
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.15 mg/liter/6 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 126°F, 52.5°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8389 at 20°C; 0.8621 at 0°C (*Merck 1983)
Vapor Pressure (mmHg): 210 at 68°F, 20°C; 135.71 at 50°F, 10°C (*Weed
Science Society of America 1974)
Melting Point: -126°F, -88°C (*Merck 1983)
Vapor Density (AIR=1): 1.94 (*Encyc Occupat Health and Safety 1983)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 2-3 parts water (*Merck 1983)
Appearance and Odor: Colorless or yellowish liquid with extremely sharp,
disagreeable, acrid, irritating odor (*Sax 1979, *CHRIS 1980)
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CAS Registry Number: 107-02-8
Page 2 of 4
ACROLEIN
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 ppm ( 0.25 mg/ms) (NIOSH 1987, p. 44)
ACGIH TLV: TWA 0.1 ppm (0.25 mg/ms); STEL 0.3 ppm (0.8 mg/m3) (*ACGIH
1983)
IDLH: 5 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: EEGL 0.05 ppm (60 minutes) (NRC 1984a,
pp. 27-34)
Routes of Entry: Inhalation: Yes (*NIOSH/RTECS 1985)
Skin: Yes (*NIOSH/RTECS 1985)
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic; probable
oral human lethal dose is 5-50 mg/kg, between 7 drops and one teaspoon for
a 70 kg (150 Ib.) person (*Gosselin 1984). Inhalation of air containing 10
ppm of acrolein may be fatal in a few minutes (*NRC 1981). Death from
cardiac failure accompanied by hyperemia and hemorrhage of the lungs and
degeneration of the bronchial epithelium is possible. Acrolein causes
acute respiratory and eye irritation; severe gastrointestinal distress with
slowly developing pulmonary edema (lungs fill up with fluid); and skin
irritation (Gosselin 1984, p. 11-186).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -15°F, -26°C (CC); less than 0°F, -18°C (OC)
(*NFPA 1978)
Flammable Limits:
LEL: 2.8% (*NFPA 1978)
UEL: 31% (*NFPA 1978)
Extinguishing Methods: Dry chemical, alcohol foam, or carbon dioxide.
Water may be ineffective, but can be used to keep containers cool (*NFPA
1978).
Special Fire Fighting Procedures: In advanced or massive fires, fire
fighting should be done from safe distance or from protected location. Use
dry chemical, alcohol foam, or carbon dioxide. Water may be ineffective,
but should be used to keep fire-exposed containers cool. If a leak or
spill has not ignited, use water spray to disperse vapors. If it is
necessary to stop a leak, use water spray to protect men attempting to do
so. Water spray may be used to flush spills away from exposures and to
dilute spills to nonflammable mixtures (*NFPA 1978). Withdraw immediately
in case of rising sound from venting safety device or any discoloration of
tank due to fire (DOT 1984, Guide 30).
Unusual Fire and Explosion Hazards: Under fire conditions, polymerization
may occur. If inside a container, violent rupture of the container may
take place (*NFPA 1978).
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CAS Registry Number: 107-02-8
Page 3 of 4
ACROLEIN
SECTION IV (continued)
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1983)
Stable:
Conditions to Avoid: Exposure to alkalis or strong acids (*Encyc
Occupat Safety and Health 1983) or to oxygen (*NFPA 1978).
Incompatibility (Materials to Avoid): Alkalis or strong acids act as
catalysts, causing a condensation reaction and liberating energy. Reaction
may be very rapid and violent (*Encyc Occupat Health and Safety 1983).
Readily converted by oxygen to hazardous peroxides and acids (*NFPA 1978).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes (*Sax 1975).
Hazardous Polymerization: May Occur: Yes (*NFPA 1978)
May Not Occur:
Conditions to Avoid: Elevated temperatures, such as fire conditions.
(Polymerization inside container could cause violent rupture of
container under fire conditions.) (*NFPA 1978)
SECTION VI -- USE INFORMATION
Acrolein is used in manufacture of colloidal forms of metals; making
plastics, perfumes; as a warning agent in methyl chloride refrigerant; and
has been used in military poison gas mixtures (*Merck 1983). It is also
used as an intermediate in the production of glycerine, methionine, acrylic
acid, and esters (*SRI). Acrolein is also an intermediate for glycerol,
polyurethane, polyester resins, and Pharmaceuticals (*Hawley 1981).
Additionally, acrolein is used as an aquatic herbicide, biocide, slimicide
(*Farm Chemicals Handbook 1984) and molluscicide (*Kearney and Kaufman
1975).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
When handling acrolein, no skin surface should be exposed (*NFPA 1978).
Remove all ignition sources. Ventilate area of spill or leak. For large
quantities, cover with sodium bisulfite, add small amount of water and mix.
Then, after 1 hour, flush with large amounts of water and wash site with
soap solution. Liquid should not be allowed to enter confined space, such
as sewer, because of possibility of explosion. Take up spill for disposal
by absorbing it in vermiculite, dry sand, or earth and disposing in a
secured landfill or combustion chamber (*NIOSH 1981).
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CAS Registry Number: 107-02-8
Page 4 of 4
ACROLEIN
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Butyl/Neoprene POOR/MANY
CPE POOR/MANY
Nitrile POOR/MANY
Viton POOR/MANY
Viton/Chlorobutyl GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 107-02-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
ACROLEIN
(107-02-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other competent
authority.
Substance Characteristics:
Pure Form - Colorless or slightly yellow liquid.
Odor - Extremely sharp.
Commercial Forms - 92 to 99% pure liquid.
Uses - Chemical intermediate, manufacture of plastics, perfumes, paper,
colloidal forms of metals, component of military poison gas mixtures and liquid
fuels, antimicrobial agent, aquatic pesticide, warning agent in methyl chloride
refrigerant.
Materials to Avoid - Acids, alkali, oxidizers, oxygen (except for use in
emergency life support).
Caution: Acrolein should not be exposed to high temperatures, acids, alkali,
or oxidizers. A violent polymerization reaction may result.
Other Names - Acquinite, acraldehyde, acrylaldehyde, acrylic aldehyde, allyl
aldehyde, ethylene aldehyde, Magnacide H, 2-propenal.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate.
Signs and Symptoms of Acute Acrolein Exposure:
Warning: Acrolein is highly irritating to skin and mucous membranes. Caution
is advised.
Signs and symptoms of acute exposure to acrolein may be severe and include
shortness of breath, tightness in the chest, pulmonary edema, and coma.
Lacrimation (tearing), nausea, vomiting, and diarrhea may also occur. Acrolein
will irritate or burn the skin and mucous membranes. Eye contact may cause
irritation, swelling, discharge, and/or corneal injury.
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EFATG
CAS Registry Number: 107-02-8
Page 2 of 3
ACROLEIN
Emergency Life-Support Procedures:
Acute exposure to acrolein may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to acrolein.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to acrolein.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible (and place in plastic
bag).
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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EFATG
CAS Registry Number: 107-02-8
Page 3 of 3
ACBOLEIN
Ingestion Exposure:
I. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 107-07-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHLOROETHANOL
CAS Registry Number: 107-07-3
Synonyms: 2-Chloroethanol; 2-Chloro-l-ethanol; 2-Chloroethyl Alcohol;
2-Hydroxyethyl Chloride; 2-Monochloroethanol; beta-Chloroethanol;
beta-Chloroethyl Alcohol; beta-Hydroxyethyl Chloride; delta-Chloroethanol;
Ethanol, 2-Chloro-; Ethene, Chlorohydrin; Ethylchlorohydrin; Ethylene
Chlorhydrin; Ethylene Glycol, Chlorohydrin; Glycol Chlorohydrin; Glycol
Monochlorohydrin; Glycomonochlorhydrin; NCI-C50135
Chemical Formula: C2H5C1O
Molecular Weight: 80.52
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.385 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 262°F, 128°C (*Weast 1979)
Specific Gravity (H2O=1): 1.197 (*Merck 1983)
Vapor Pressure (mmHg): 4.9 (*Clayton and Clayton 1981-82)
Melting Point: -89.5°F, -67.5°C (*Weast 1979)
Vapor Density (AIR=1): 2.78 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (*Weast 1979)
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CAS Registry Number: 107-07-3
Page 2 of 4
CHLOROETHANOL
SECTION II (continued)
Appearance and Odor: Colorless, glycerine-like liquid (*Browning 1965);
faint ethereal odor (*Sax 1979); sweet, pleasant odor (*CHRIS 1978)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 ppm (16 mg/m3) (NIOSH 1987, p. 120)
ACGIH TLV: Ceiling 1 ppm (3 mg/ms) (skin) (ACGIH 1986-87, p. 18)
IDLH: 10 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and Safety
1983)
Skin: Yes (*Encyc Occupat Health and Safety 1983)
Ingestion: Yes (*Encyc Occupat Health and Safety
1983)
Health Hazards (Acute, Delayed, and Chronic): Very toxic; probable oral
lethal dose in humans is 50-500 rag/kg or between 1 teaspoon and 1 ounce for
a 70 kg (150 Ib.) person (*Gosselin 1976). Poisoning causes liver and
kidney degeneration and irritates mucous membranes; it may be cumulative
(*Merck 1983). Several fatal cases with brain edema and lung edema have
been reported from industrial exposure by inhalation and skin contact
(*Encyc Occupat Health and Safety 1983). It is more toxic by skin contact
than orally (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 105°F (OC) (*Merck 1983); 140°F, 60°C (CC)
(*NFPA 1978)
Flammable Limits:
LEL: 4.9% (*NFPA 1978)
UEL: 15.9% (*NFPA 1978)
Extinguishing Methods: Water spray may be used to extinguish the fire
because the material can be cooled below its flash point (*NFPA 1978).
Alcohol foam, carbon dioxide, and dry chemical may be used (*CHRIS 1978).
Special Fire Fighting Procedures: Do not breathe fumes from burning
material. Air purifying respirator or self-contained breathing apparatus,
coat, pants, gloves, and boots should be worn. No skin surface should be
exposed. Bands around legs, arm and waist should be provided (*NFPA 1978).
Unusual Fire and Explosion Hazards: Its decomposition products will react
with water or steam to produce toxic and corrosive fumes (*Sax 1979).
Vapors are heavier than air and may flash back to a source of ignition
(*CHRIS 1978).
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CAS Registry Number: 107-07-3
Page 3 of 4
CHLOROETHANOL
SECTION IV (continued)
NFPA Flammability Rating: 2
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits highly toxic fumes of phosgene (*Sax 1979). Hydrogen chloride fumes
may be formed (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Manufacture of insecticides; treating sweet potatoes before planting
(*Merck 1983); introduction of hydroxyethyl group in organic synthesis;
used as a solvent (*Hawley 1981); employed in separating butadiene from
hydrocarbon mixtures (*Clayton and Clayton 1981-82); intermediate for
indigo and thiodiethylene glycol (*SRI); used for removal of tar spots; and
cleaning agent for machines (*Browning 1965)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Remove all ignition sources. Ventilate area of spill or leak. For small
quantities, absorb on paper towels. Evaporate in a safe place (such as a
fume hood). Allow sufficient time for evaporating vapors to completely
clear the hood ductwork. Burn the paper in a suitable location away from
combustible materials. Large quantities can be collected and atomized in a
suitable combustion chamber equipped with an appropriate effluent gas
cleaning device. It should not be allowed to enter a confined space, such
as a sewer, because of the possibility of an explosion. Absorb it in
vermiculite, dry sand, earth or a similar material and dispose in a secured
sanitary landfill (*NIOSH/OSHA 1981). Do not touch material and do
not expose skin (*CHRIS 1978; *Clayton and Clayton 1981-82).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
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CAS Registry Number: 107-07-3
Page 4 of 4
CHLOROETHANOL
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Butyl/Neoprene POOR/LIMITED*
Neoprene GOOD/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX » EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 107-07-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
CHLOROETHANOL
(107-07-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless, glycerinelike liquid.
Odor - Faint, sweet, pleasant.
Commercial Form - Liquid in bottles, jugs, carboys, or tank cars.
Uses - Chemical intermediate, organic synthesis, manufacture of insecticides,
solvent, cleaning agent.
Caution: When heated to decomposition, highly toxic fumes of phosgene and
hydrogen chloride gas may be generated. Refer to the appropriate Emergency
First Aid Treatment Guide for these substances.
Other Names - 2-Chloroethanol, ethylchlorohydrin, ethylene chlorohydrin, glycol
chlorohydrin, 2-hydroxyethyl chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, dopamine, norepinephrine.
Signs and Symptoms of Acute Chloroethanol Exposure:
Signs and symptoms of acute exposure to Chloroethanol may include weakness,
dizziness, confusion, visual disturbances, incoordination, shock, seizures, and
coma.
Dyspnea (shortness of breath), pulmonary edema, respiratory depression, and
respiratory failure may occur. Weak pulse, hypotension (low blood pressure),
and cyanosis (blue tint to the skin and mucous membranes) may be observed.
Nausea, vomiting, and hematuria (bloody urine) may be seen after exposure.
Liver and kidney damage may also occur. Chloroethanol is irritating to the
skin and mucous membranes.
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EFATG
CAS Registry Number: 107-07-3
Page 2 of 3
CHLOROETHANOL
Emergency Life-Support Procedures:
Acute exposure to chloroethanol may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to chloroethanol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to chloroethanol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 107-07-3
Page 3 of 3
CHLOROETHANOL
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 107-11-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ALLYLAMINE
CAS Registry Number: 107-11-9
Synonyms: 2-Propen-l-amine; 2-Propenylamine; 3-Amino-l-Propene;
3-Aminopropene; 3-Aminopropylene; Monoallylamine
Chemical Formula: CSH7N
Molecular Weight: 57.09
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mammal) 0.32 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 131-136°F, 55-58°C (*Merck 1976)
Specific Gravity (H2O=1): 0.76 at 20°C/20°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 2.0 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1976)
Appearance and Odor: A colorless to light yellow liquid (*NFPA 1984),
strong ammonia odor (*Merck 1976).
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CAS Registry Number: 107-11-9
Page 2 of 4
ALLYLAMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*NFPA 1978)
Skin: Yes (*NFPA 1978)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Acute: an eye, skin, and
respiratory tract irritant (*NFPA 1978) which is highly toxic if inhaled or
ingested and moderately toxic if absorbed on skin. Ingestion or inhalation
may cause death or permanent injury after very short exposure to small
quantities. Skin absorption may cause irreversible and reversible changes
(*Sax 1975). Toxic air concentration (TCi0) in humans is 5 ppm over 5
minutes (*NIOSH/RTECS 1985). Vapors are extremely unpleasant and may
ensure voluntary avoidance of dangerous concentrations (*Grant 1974). Will
irritate nose and throat at 2.5 ppm (*Patty 1963).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -20°F (CC) (*NFPA 1978)
Flammable Limits:
LEL: 2.2% (*NFPA 1978)
UEL: 22% (*NFPA 1978)
Extinguishing Methods: Wear self-contained breathing apparatus and full
protective clothing (*NFPA 1978). Use dry chemical, alcohol foam, or
carbon dioxide. Water may be used to keep exposed containers cool (*NFPA
1978). Dike fire control water for later disposal. Withdraw immediately
in case of rising sound from venting safety device or discoloration of tank
due to fire (*DOT 1984).
Special Fire Fighting Procedures: Keep unnecessary people away and
isolate hazard area. Stay upwind and keep away from low areas. Isolate
for 1/2 mile in all directions if tank car or truck is involved (*DOT
1984).
Unusual Fire and Explosion Hazards: Flammable when exposed to heat,
sparks, or flame (*Sax 1975). Vapor forms explosive mixtures with air over
a wide range. Use caution when approaching fire and applying water (*NFPA
1978). Vapor explosion and poison hazard indoors, outdoors or in sewers.
Runoff to sewer may create fire or explosion hazard (*DOT 1984). Can react
with oxidizing materials. When heated to decomposition, it emits toxic
fumes (*Sax 1975).
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CAS Registry Number: 107-11-9
Page 3 of 4
ALLYLAMINE
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA (continued)
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Avoid heating to decomposition (*Sax 1978). May
become unstable at elevated temperatures and pressures or may react
with water with non-violent release of energy (*NFPA 1978).
Incompatibility (Materials to Avoid): Oxidizing materials (*Sax 1975).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a chemical intermediate for mercurial diuretics (*SRI), as a
pharmaceutical intermediate and in organic synthesis (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
For leaks or spills, use water spray to disperse vapors and protect men
attempting to stop leak. Water spray may be used to flush spills away from
exposures and to dilute spills to nonflammable mixtures (*NFPA 1978). Shut
off ignition sources and keep away all flames, smoking, or flares. Do not
touch spilled material. Take up small spills with sand or other
noncombustible absorbent material and place in containers for later
disposal. For large spills, dike far ahead for later disposal (*DOT 1984).
Local exhaust or general ventilation methods should be used in enclosed
spaces (*Sax 1975). Do not breathe vapors (See Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 107-11-9
Page 4 of 4
ALLYLAMINE.
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
PVC POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include irritation of nose,
eyes, and mouth with tearing, runny nose, and sneezing (*Patty 1963). Can
cause excitement, convulsions, and death (*Merck 1976).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. Remove and isolate contaminated clothing and shoes
at site. In case of contact, flush skin or eyes with water for 15 minutes.
Keep victim quiet and maintain normal body temperature. Keep victim under
careful watch since effects may be delayed (DOT 1984, Guide 28).
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CAS Registry Number: 107-12-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROPIONITRILE
CAS Registry Number: 107-12-0
Synonyms: Cyanoethane; Ether Cyanatus; Ethyl Cyanide; Hydrocyanic Ether;
Propanenitrile; Propionic Nitrile; Propiononitrile; Propylnitrile
Chemical Formula: C3H5N
Molecular Weight: 55.08
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.37 mg/liter/hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 207°F, 97.2°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8020 at 0°C/4°C ('Merck 1983)
Vapor Pressure (mmHg): 40 at 22°C (*Clayton and Clayton 1981-82)
Melting Point: -133°F, -9l.8°C (*Merck 1983)
Vapor Density (AIR=1): 1.9 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 11.9 g/100 ml at 40°C (*Merck 1983)
Appearance and Odor: Colorless (*Clayton and Clayton 1981-82) liquid
(Hawley 1981, p. 1428); pleasant, ethereal, sweetish odor (*Merck 1983)
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CAS Registry Number: 107-12-0
Page 2 of 4
PROPIONITRILE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Occupational exposure to nitriles recommended
standard, air: TWA 14 mg/ms (*NIOSH/RTECS 1985). Maximum allowable
concentration (USSR) 0.3 mg/ms (as HCN) (Encyc Occupat Health and Safety
1983, p. 1445).
Routes of Entry: Inhalation: Yes (*Deichman 1969)
Skin: Yes (*Deichman 1969)
Ingestion: Yes (Sax 1984, p. 2300)
Health Hazards (Acute, Delayed, and Chronic): It is highly toxic (*Encyc
Occupat Health and Safety 1981). This super toxic compound has a probable
oral lethal dose in humans of less than 5 mg/kg or a taste (less than 7
drops) for a 70 kg (150 Ib.) person (*Gosselin 1976). It is a mild to
moderate skin and eye irritant (Weiss 1980, p. 1145).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 2°C (CC) (*Bretherick 1979)
Flammable Limits:
LEL: 3.1% (*Bretherick 1979)
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, and foam. Large fires: water spray, fog, or foam. Move containers
from fire area if you can do it without risk. Dike fire control water for
later disposal; do not scatter the material. Cool containers that are
exposed to flames with water from the side until well after fire is out.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire (DOT 1984, Guide 28).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
positive pressure breathing apparatus and special protective clothing.
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides and cyanide (Sax 1984, p. 2300). It
is a flammable/combustible material and may be ignited by heat, sparks or
flames. Vapors may travel to a source of ignition and flash back.
Container may explode in heat of fire. Vapor explosion and poison hazard
indoors, outdoors or in sewers. Runoff to sewer may create fire or
explosion hazard (DOT 1984, Guide 28).
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CAS Registry Number: 107-12-0
Page 3 of 4
PROPIONITRILE
SECTION IV (continued)
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: May become unstable at elevated temperatures and
pressures (*NFPA 1978).
Incompatibility (Materials to Avoid): Generates cyanide ions (*Peer
Review Committee). Poisonous on contact with acids (*Merck 1983).
Hazardous Decomposition or Byproducts: Poisonous when heated to
decomposition (*Merck 1983). When heated to decomposition, it emits toxic
fumes of nitrogen oxides and cyanides (Sax 1984, p. 2300).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as a setting agent for resins; a raw material for some medicines
(*Rumack 1975 to Present) and a chemical intermediate for di-n-propylamine
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors and skin contact (see Section III above). Shut off
ignition sources; no flares, smoking or flames in hazard area. Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 107-12-0
Page 4 of 4
PROPIONITRILE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
PVC POOR/MANY
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death (*NFPA 1978). Exposure
results in headache, dizziness, rapid pulse, deep-rapid breathing, nausea,
vomiting, unconsciousness, convulsions and sometimes death (*Rumack 1975 to
Present). Chronic exposure over long periods may cause fatigue and
weakness (*Merck 1968). Can cause same general symptoms as hydrogen
cyanide but onset of symptoms is likely to be slower (*Clayton and Clayton
1981-82). Contact may cause burns to skin and eyes (DOT 1984, Guide 28).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes
(DOT 1984, Guide 28).
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CAS Registry Number: 107-13-1
Page 1 of 5
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ACRYLONITRILE
CAS Registry Number: 107-13-1
Synonyms: 2-Propenenitrile; Acrylon; Acrylonitrile Monomer; Cyanoethylene;
ENT 54; Fumigrain; Miller's Fumigrain; NCI-C50215; Propenenitrile; TL 314; VCN;
Vinyl Cyanide
Chemical Formula: C3H3N
Molecular Weight: 53.60
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: Chemical does not
meet the toxicity criteria but because of its high production volume
and recognized toxicity it is considered a chemical of concern.
TPQ: 10,000 (pounds)
RQ: 100 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 171°F, 77.3°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8004 at 25°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 100 at 23°C (*IARC 1972-1985)
Melting Point: -116°F, -82.0°C (*Sax 1979)
Vapor Density (AIR=1): 1.9 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 7.35 parts dissolve in 100 parts water at 20°C
(*Merck 1983)
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CAS Registry Number: 107-13-1
Page 2 of 5
ACRYLONITRILE
SECTION II (continued)
Appearance and Odor: Clear, colorless liquid (some technical grades
slightly yellow) with a very slight odor of peach pits (*Clayton and
Clayton 1981-82; *Lefaux 1968)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 2 ppm; Ceiling 10 ppm/15 minutes (NIOSH 1987, p. 46)
ACGIH TLV: TWA 2 ppm (4.5 mg/m8) (skin) (ACGIH 1986-87, p. 9)
IDLH: 500 ppm (NIOSH/OSHA Joint Standards Completion Project, 1975)
Other Limits Recommended: Industrial substance suspect of carcinogenic
potential for man (ACGIH 1986-87, p. 40). NIOSH: 1 ppm 8-hour TWA, 10
ppm 15-minute ceiling; potential occupational carcinogen (NIOSH 1987, p. 46)
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): It is classified as very
toxic. Probable oral lethal dose for human is 50-500 mg/kg (between 1
teaspoon and 1 oz.) for a 70 kg (150 Ib.) person. Irritant skin dose --
500 mg. Toxic concentrations have been reported at 16 ppm/20 min.
(*Gosselin 1976). Acute toxicity is similar to that due to cyanide
poisoning and the level of cyanide ion in blood is related to the level of
poisoning (*Clayton and Clayton 1981-82). Inhalation or ingestion results
in collapse and death due to tissue anoxia (lack of oxygen) and cardiac
arrest (heart failure) (*Encyc Occupat Health and Safety 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 32°F, 0°C (*Merck 1983)
Flammable Limits:
LEL: 3% (*NFPA 1978)
UEL: 17% (*NFPA 1978)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog or foam. Stay away from
ends of tanks. Do not get water inside container. Cool containers that
are exposed to flames with water from the side until well after fire is
out. For massive fire in cargo area, use unmanned hose holder or monitor
nozzles; if this is impossible, withdraw from area and let fire burn.
Withdraw immediately in case of rising sound from venting safety device or
any discoloration of tank due to fire (*DOT 1984).
Special Fire Fighting Procedures: In advanced or massive fires, fire
fighting should be done from a safe distance or a protected location (*NFPA
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CAS Registry Number: 107-13-1
Page 3 of 5
ACRYLONITRILE
SECTION IV (continued)
1978). Isolate for 1/2 mile in all directions if tank car or truck is
involved in fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Materials are too dangerous to health
to expose fire fighters. A few whiffs of vapor could cause death or vapor
or liquid could be fatal on penetrating the fire fighter's normal full
protective clothing. The normal full protective clothing and breathing
apparatus available to the average fire department will not provide
adequate protection against inhalation or skin contact with these materials
(*NFPA 1978). Explosion hazard is moderate. It is flammable and explosive
at normal room temperatures (*Encyc Occupat Health and Safety 1971). Can
react violently with strong acids, amines, strong alkalis (*Sax 1979).
Vapors may travel considerable distance to source of ignition and flash
back. Dilute solutions are also hazardous (flash point of a solution of 2
percent in water is 70°F) (*NFPA 1978).
NFPA Flammability Rating: 3
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Clayton and Clayton 1981-82)
Stable:
Conditions to Avoid: Moderate hazard is possible when it is exposed
to flames, strong acids, amines and alkalis (*Sax 1979).
Incompatibility (Materials to Avoid): Avoid strong acids, amines, alkalis
(*Sax 1979). Also, incompatible with strong oxidizers (especially bromine)
copper and copper alloys (NIOSH/OSHA 1978, p. 42).
Hazardous Decomposition or Byproducts: When heated or burned, toxic
hydrogen cyanide gas and oxides of nitrogen are formed (*CHRIS 1978).
Hazardous Polymerization: May Occur: Yes (*NFPA 1978)
May Not Occur:
Conditions to Avoid: May polymerize spontaneously in the container,
particularly in absence of oxygen or on exposure to visible light
(*Merck 1983). If polymerization occurs in containers, there is a
possibility of violent rupture (*NFPA 1978).
SECTION VI ~ USE INFORMATION
Used primarily in plastics manufacturing as a copolymer and comonomer
(*SRI); to improve dye and working properties of acrylic fibers (*Hamilton
1974); formerly used as a fumigant for food commodities (*Farm Chemicals
Handbook 1983).
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CAS Registry Number: 107-13-1
Page 4 of 5
ACRYLONITRILE
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no flares, smoking or flames in hazard area.
Do not touch material; stop leak if you can do so without risk. Use water
spray to reduce vapors; do not get water inside container.
Small spills: flush area with flooding amounts of water.
Large spills: dike far ahead of spill for later disposal (*DOT 1984).
If leak or spill has not ignited, use water spray to disperse vapors
(*NFPA 1978).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
CPE POOR/LIMITED
Neoprene GOOD/LIMITED*
Nitrile POOR/LIMITED*
PE POOR/MANY
PVC POOR/LIMITED*
Saranex POOR/LIMITED
Teflon POOR/LIMITED
Viton POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Acrylonitrile reaction causes redness,
blisters and some systemic signs (*Gosselin 1976). Symptoms derive from
tissue anoxia in order of onset: limb weakness, dyspnea (difficult
breathing), burning sensation in throat, dizziness, impaired judgment,
cyanosis (turning blue), nausea, collapse, irregular breathing, convulsions
and death. In later stages collapse, irregular breathing or convulsions
and cardiac arrest may occur without warning. Some patients appear
hysterical or may even be violent (*Encyc Occupat Health and Safety 1983).
Emergency and First Aid Procedures: Get emergency medical treatment
immediately. If victim has taken the substance by ingestion (orally) and
is not showing symptoms, give syrup of ipecac with salt solution or water.
If there is exposure through skin contact, wash twice with soap and water.
Exposed eyes should be flushed copiously with water for at least 15
minutes. If the victim stops breathing before emergency medical treatment
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CAS Registry Number: 107-13-1
Page 5 of 5
ACRYLONITRILE
is available, give artificial respiration or oxygen but avoid mouth to
mouth resuscitation; also avoid contact with contaminated skin (Gosselin
1984, p. III-127; *Rumack 1985).
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CAS Registry Number: 107-15-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ETHYLENEDIAMINE
CAS Registry Number: 107-15-3
Synonyms: 1,2-Diaminoethane; 1,2-Ethanediamine; 1,2-Ethylenediamine; beta-
Aminoethylamine; Dimethylenediamine; Ethylendiamine
Chemical Formula: C2H8N2
Molecular Weight: 60.12
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.3 mg/liter (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 5,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 241°F, 116°C (*Merck 1983)
Specific Gravity (H2O=1): 0.898 at 25°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 10.7 at 20°C (*Hawley 1981)
Melting Point: 46°F, 8°C (*Merck 1983)
Vapor Density (AIR=1): 2.07 (*Sax 1975)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble in water (*Weast 1979)
Appearance and Odor: Colorless, thick liquid (*Sax 1975); ammonia-like
odor (*Encyc Occupat Health and Safety 1983)
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CAS Registry Number: 107-15-3
Page 2 of 4
ETHYLENEDIAMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 10 ppm (25 mg/ms) (*NIOSH/OSHA 1978)
ACGIH TLV: TWA 10 ppm (25 mg/m3) (*ACGIH 1983)
IDLH: 2000 ppm (*NIOSH/OSHA 1978)
Other Limits Recommended: Maximum allowable concentration (USSR):
2 mg/m8 (Encyc Occupat Health and Safety 1983, p. 141)
Routes of Entry: Inhalation: Yes (*Arena 1979)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Vapor inhalations at a
concentration of 200 ppm for 5 to 10 minutes will lead to nasal irritation
and produce a tingling sensation. Inhalation at concentrations of 400 ppm
or greater leads to severe nasal irritation (*Clayton and Clayton 1981-82).
Respiratory irritation may result (Gosselin 1984, p. 11-206). Many
individuals are hypersensitive to ethylenediamine exposure; therefore, safe
threshold limits are difficult to set (*ACGIH 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 93°F, 34°C (CC); 150°F, 66°C (OC) (*NFPA 1978)
Flammable Limits:
LEL: 4.2% (*NFPA 1978)
UEL: 14.4% (*NFPA 1978)
Extinguishing Methods: Use water spray, dry chemical, alcohol foam, or
carbon dioxide (*NFPA 1978).
Special Fire Fighting Procedures: Wear full protective clothing including
gloves and boots. If necessary to enter closed area, wear full-faced gas
masks with self-contained breathing apparatus. Do not use water in case of
drum or tank fires (*CHRIS 1978). If a leak or spill has not ignited, use
water spray to reduce the vapors and dilute spills to nonflammable
mixtures. Use water to keep fire-exposed containers cool (*NFPA 1978).
Unusual Fire and Explosion Hazards: Burning rate: 2.2 mm/minute (*CHRIS
1978). When exposed to heat or flame, the material has a moderate fire
potential. The material can react readily with oxidizing materials (*Sax
1975). Containers may explode in heat of fire (*DOT 1984).
NFPA Flammability Rating: 2
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CAS Registry Number: 107-15-3
Page 3 of 4
ETHYLENEDIAMINE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Carbon disulfide (*NRC 1981);
silver perchlorate (*NFPA 1978); imines (*Leleu MJ. 1979. CAH Notes Doc.
94:127-132); oxidizing materials (*Sax 1975).
Hazardous Decomposition or Byproducts: Material emits nitrogen oxides
when burned (*Rumack 1975 to Present).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 430)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
A solvent for casein, albumin, shellac, and sulfur; an emulsifier;
stabilizer for rubber latex; inhibitor in antifreeze solutions;
pharmaceutic aid (*Merck 1983); intermediate in synthesis of carbamate
fungicides and chelating agents (*SRI). An algacide and fungicide
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources. Stop leak if possible without risk. Do not
touch spilled material. Use water spray to reduce vapors. Do not get
water inside containers. For small spills, absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. For large spills, dike far ahead of spill for later disposal.
Keep unnecessary people away and isolate area. Stay upwind and keep out of
low areas. Isolate area for 1/2 mile in all directions if tank car or truck
is involved in fire (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 107-15-3
Page 4 of 4
ETHYLENEDIAMINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
Butyl/Neoprene POOR/LIMITED*
CPE POOR/LIMITED
Neoprene GOOD/LIMITED
PE POOR/LIMITED
PVC POOR/MANY
Saranex GOOD/LIMITED
Teflon GOOD/LIMITED
Viton/Neoprcne POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 107-J5-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
ETHYLENEDIAMINE
(107-15-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless, thick liquid.
Odor - Ammonialike.
Commercial Forms - Liquid shipped in glass bottles; 1- to 5-gallon cans;
55-gallon, tin-lined drums; and tank cars.
Uses - Solvent, emulsifier, stabilizer, chemical intermediate, component of
antifreeze solutions, herbicide.
Materials to Avoid - Oxidizers.
Caution: Flammable liquid. Avoid sources of ignition including sparks or
fire. When burned, ethylenediamine will emit toxic nitrogen oxides.
Other Names - 1,2-Diaminoethane, 1,2-ethanediamine.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, milk, normal saline, D5W,
Ringer's lactate, decadron.
Signs and Symptoms of Acute Ethylenediamine Exposure:
Acute exposure to ethylenediamine may result in cough, difficulty in breathing,
irritation of the lungs, and pneumonia. Nausea, vomiting, and diarrhea are
often seen. Contact with ethylenediamine may result in redness, pain,
irritation, and burns.
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EFATG
CAS Registry Number: 107-15-3
Page 2 of 3
ETHYLENEDIAMINE
Emergency Life-Support Procedures:
Acute exposure to ethylenediamine may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to ethylenediamine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to ethylenediamine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Thoroughly wash exposed skin areas with water for at least 15 minutes.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 107-15-3
Page 3 of 3
ETHYLENEDIAMINE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
6. Transport to a health care facility.
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CAS Registry Number: 107-16-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FORMALDEHYDE CYANOHYDRIN
CAS Registry Number: 107-16-4
Synonyms: Acetonitrile, Hydroxy-; 2-Hydroxyacetonitrile; alpha-
Hydroxyacetonitrile; alpha-Hydroxymethylcyanide; Cyanomethanol; Glycolic
Nitrile; Glyconitrile; Hydroxyacetonitrile; Hydroxymethylnitrile; Methylene
Cyanohydrin; USAF A-8565
Chemical Formula: C2H3NO
Molecular Weight: 57.06
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 skin
(rabbit) 5.0 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 361°F, 183°C, with slight decomposition (*Weast 1979)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 1 at 63°C (*Patty 1963)
Melting Point: Less than r98°F, less than -72°C (*Weast 1979)
Vapor Density (AIR=1): 1.96 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Patty 1963)
Appearance and Odor: Colorless oil (*Sax 1979); odorless (*Encyc Occupat
Health and Safety 1971}; sweetish taste (*Patty 1963)
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CAS Registry Number: 107-16-4
Page 2 of 4
FORMALDEHYDE CYANOHYDRIN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Recommended NIOSH standard air ceiling
concentration is 5 mg/ms/15 minutes (*NIOSH/RTECS 1985).
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Hawley 1977)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic (*Patty
1963); exposure by any route should be avoided; may have fatal
consequences; death from asphyxiation may occur similar to that resulting
from hydrogen cyanide (*Encyc Occupat Health and Safety 1971).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Acetonitrile) Do not extinguish
fire if material is leaking and flow cannot be stopped. Use water in
flooding quantities as fog. Use alcohol foam, carbon dioxide, or dry
chemical (Student 1981, pp. 3-4).
Special Fire Fighting Procedures: (Non-Specific -- Acetonitrile) Cool
containers with flooding quantities of water. Apply water from as far away
as possible. Avoid breathing vapors. Keep upwind. Wear self-contained
breathing apparatus. Avoid bodily contact with the material. Wear boots,
protective gloves, and goggles (Student 1981, pp. 3-4).
Unusual Fire and Explosion Hazards: Moderate explosion hazard when
exposed to heat or by spontaneous chemical reaction in the presence of
alkalies if uninhibited (*Sax 1979). When heated to decomposition, it
emits toxic fumes of cyanide and nitrogen oxides (Sax 1984, p. 1556).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Bretherick 1979)
Stable:
Conditions to Avoid: May explode on standing (*Bretherick 1979).
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CAS Registry Number: 107-16-4
Page 3 of 4
FORMALDEHYDE CYANOHYDRIN
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic cyanide and nitrogen oxide fumes (Sax 1984, p. 1556)
Hazardous Polymerization: May Occur: Yes (*Sax 1979)
May Not Occur:
Conditions to Avoid: Presence of alkalies, and exposure to heat (*Sax
1979)
SECTION VI - USE INFORMATION
This material is used in the manufacture of intermediates in pharmaceutical
production and as a component of synthetic resins (*Encyc of Occupat Health
and Safety 1971), as a chemical intermediate for organic compounds, and as
a solvent (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Acetonitrile) Build dikes to contain flow as necessary.
Use water spray to disperse vapors and dilute standing pools of liquid.
Avoid breathing vapors. Keep upwind. Avoid bodily contact with the
material (Student 1981, pp. 3-4).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Similar to cyanide poisoning. Odor of
bitter almonds on patient's breath may or may not be present. Vomiting,
palpitations, confusion, anxiety, and vertigo may follow exposure.
Respiration may initially be rapid, then slow and labored, followed by coma
and convulsions (*Rumack 1975 to Present). ;
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CAS Registry Number: 107-16-4
Page 4 of 4
FORMALDEHYDE CYANOHYDRIN
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specific -- Acetonitrile) Move
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Remove
and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 28).
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CAS Registry Number: 107-18-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ALLYL ALCOHOL
CAS Registry Number: 107-18-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 308) AA; Allyl Al;
Ally lie Alcohol; 2-Propen-l-ol; Vinylcarbinol; Propenyl Alcohol;
l-Propene-3-ol; 3-Hydroxypropene; Orvinylcarbinol; Propenol; Propen-l-ol-3;
2-Vinylcarbinol; 2-Propenyl Alcohol; Shell Unkrautted A; Weed Drench
Chemical Formula: CSH6O
Molecular Weight: 58.09
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.39 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 206°F, 97°C (*Merck 1976)
Specific Gravity (H2O=1): 0.854 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 23.8 at 25°C (*Sunshine 1969)
Melting Point: -200°F, -129°C; freezes at -50°C (Weast 1980, p. C-466)
Vapor Density (AIR=1): 2.0 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Weast 1979)
Appearance and Odor: Mobile, colorless liquid with a pungent mustard odor
(*Merck 1976, *Martin 1974). Forms a glass at -190°C (*Worthing 1979).
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CAS Registry Number: 107-18-6
Page 2 of 4
ALLYL ALCOHOL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 2 ppm (5 mg/ms) (NIOSH 1987, p. 46)
ACGIH TLV: TWA 2 ppm (5 mg/ms); STEL 4 ppm (10 mg/ms) (skin)
(ACGIH 1986-87, p. 9)
IDLH: 150 ppm (NIOSH/OSHA 1978, p.44)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 63)
Skin: Yes (Weiss 1980, p. 63)
Ingestion: Yes (Weiss 1980, p. 63)
Health Hazards (Acute, Delayed, and Chronic): Allyl alcohol is an intense
irritant to skin, eyes, nose, and throat (Weiss 1980, p. 63). It causes
burns on contact, and may cause pulmonary edema if inhaled. It is
poisonous in small quantities. The probable oral lethal dose is 50-500
mg/kg, or between 1 teaspoonful and 1 ounce for a 150-lb. person (Gosselin
1984, p. 11-98).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 22°C (CC), 32°C (OC) (*Patty 1963)
Flammable Limits:
LEL: 2.5% (*Sunshine 1969)
UEL: 18% (*Sunshine 1969)
Extinguishing Methods: Extinguish with dry chemical, alcohol foam, or
carbon dioxide (*NFPA 1978). Dike fire control water for later disposal
and do not scatter the material (DOT 1984, Guide 28).
Special Fire Fighting Procedures: Water may be ineffective on fire. Cool
exposed containers with water. Wear goggles, self-contained breathing
apparatus, rubber overclothing, gloves (Weiss 1980, p. 63). Isolate
for 1/2 mile in all directions if tank car or truck is involved in fire
(DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Allyl alcohol vapor may explode if
ignited in confined areas. Combustion products may be poisonous. The
vapor is heavier than air and flashback along vapor trail may occur (Weiss
1980, p. 63). Gives off toxic fumes when heated (*NFPA 1978).
NFPA Fiammability Rating: 3
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
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CAS Registry Number: 107-18-6
Page 3 of 4
ALLYL ALCOHOL
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): May react vigorously with oxidizing
materials, carbon tetrachloride, acids, oleum, sodium hydroxide, diallyl
phosphite, potassium chloride, or tri-n-bromomelamine (Sax 1984, p. 159).
Hazardous Decomposition or Byproducts: Gives off toxic fumes when heated
(*NFPA 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Allyl alcohol is used in the production of allyl esters, which are used as
monomers and prepolymers in the manufacture of resins and plastics. It is
also used in the preparation of Pharmaceuticals, organic synthesis of
glycerol and acrolein, and as a fungicide and herbicide (*SRI; *Merck 1976;
*Browning 1965).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
• Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Wear positive pressure breathing apparatus
and special protective clothing. Shut off ignition sources; no
flares, smoking or flames in hazard area. Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl EXCELLENT/MANY
Butyl/Neoprene GOOD/LIMITED
CPE GOOD/LIMITED
Neoprene EXCELLENT/MANY
PE GOOD/LIMITED
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CAS Registry Number: 107-18-6
Page 4 of 4
ALLYL ALCOHOL
SECTION VIII (continued)
PVC POOR/MANY
Saranex GOOD/LIMITED
Teflon GOOD/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 107-18-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
ALLYL ALCOHOL
(107-18-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Pungent, mustardlike.
Commercial Form - Liquid in 1- and 5-gallon cans, drums, tank trucks, tank
cars, tank barges.
Uses - Fungicide, herbicide, chemical intermediate for the manufacture of
chemicals and chemical warfare agents.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire.
Other Names - Allylic alcohol, 3-hydroxypropene, orvinylcarbinol, 2-propen-l-
ol, 2-propenyl alcohol, vinylcarbinol, Weed Drench.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate,
diazepam, dopamine, levarterenol.
Signs and Symptoms of Acute AHyl Alcohol Exposure:
Warning: Effects may be delayed. Caution is advised.
Signs and symptoms of acute exposure to allyl alcohol may be severe and include
eye and skin irritation, pain, burns, and ulceration. Lacrimation (tearing),
blurred vision, and photophobia (heightened sensitivity to light) are common;
permanent eye damage may occur. Nose and throat irritation, headache, cough,
dyspnea (shortness of breath), and hemoptysis (spitting up of blood) may be
noted. Nausea, vomiting, and hematuria (bloody urine) may also occur. Liver
and kidney damage have bgen reported in study animals.
-------
EFATG
CAS Registry Number: 107-18-6
Page 2 of 3
ALLYL ALCOHOL
Emergency Life-Support Procedures:
Acute exposure to allyl alcohol may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to allyl alcohol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to allyl alcohol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 107-18-6
Page 3 of 3
ALLYL ALCOHOL
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of allyl alcohol is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have .an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 107-30-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHLOROMETHYL METHYL ETHER
CAS Registry Number: 107-30-2
Synonyms: Chlorodimethyl Ether; Chloromethoxymethane; CMME; Dimethyl-
chloroether; Ether, Chloromethyl Methyl; Ether Dimethyl Chloro; Methane,
Chloromethoxy-; Methoxychloromethane; Methoxymethyl Chloride;
Methylchloromethyl Ether; Methylchloromethyl Ether, Anhydrous;
Monochlorodimethyl Ether; Monochloromethyl Methyl Ether
Chemical Formula: C2H5C1O
Molecular Weight: 80.52
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.182 mg/liter/7 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 138°F, 59°C (*IARC 1972-1985)
Specific Gravity (H2O=1): 1.0605 at 20°/4°C (*IARC 1972-1985)
Vapor Pressure (mmHg): Not Found
Melting Point: -154.3°F, -103.5°C (*Encyc Occupat Health and Safety 1971)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Weast 1979, p. C-300)
Appearance and Odor: Colorless liquid with an irritating odor (*IARC
1972-1985, *CHRIS 197~8)
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CAS Registry Number: 107-30-2
Page 2 of 4
CHLOROMETHYL METHYL ETHER
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 2 ppm (2 mg/m8) (ACGIH 1986-87, p. 13)
IDLH: Not Found
Other Limits Recommended: Industrial substance suspect of carcinogenic
potential for humans (ACGIH 1984, p. 43).
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): The principal effect is
irritation. The liquid causes severe irritation of eyes and skin; and
vapor exposure of 100 ppm is severely irritating to eyes and nose. This
level is dangerous to life in 4 hours. Pulmonary edema or pneumonia may
cause death (*Encyc Occupat Health and Safety 1971). There was increased
death rate from respiratory cancer among exposed victims (*IARC 1972-1985)
and it is a regulated carcinogen (*Aldrich 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 0°C (OC) (*CHRIS 1978); less than 73.4°F (Sax
1984, p. 738)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemicals, foam, or carbon
dioxide. Water may be ineffective in extinguishing fire ("CHRIS 1978).
Special Fire Fighting Procedures: Move container from fire area. Dike
fire control water for later disposal; do not scatter material. Cool
containers that are exposed to flames with water. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Flammable/combustible material; may
be ignited by heat, sparks, or flames. Vapors may travel to a source of
ignition and flash back. Container may explode in heat of fire (*DOT
1984). In addition to the risk of explosion, when air mixtures of ether
vapors are heated or exposed to flame or sparks, they tend to form
peroxides. Ethers containing peroxides can detonate when heated (*Sax
1975). Unburned material may form powerful tear gas. When wet, also forms
irritating formaldehyde gas (Weiss 1980, p. 251).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 107-30-2
Page 3 of 4
CHLOROMETHYL METHYL ETHER
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*CHRIS 1978)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 738)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Evolves formaldehyde and hydrogen
chloride (*CHRIS 1978). When heated to decomposition, it emits toxic fumes
of chlorides (Sax 1984, p. 738).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 251)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Intermediate in synthesis of chloromethylated compounds (*IARC 1972-1985); a
nion-exchange resins; dodecylbenzyl chloride; and chloromethylating
reaction mixtures (*SRI).
SECTION VII » PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no flares, smoking, or flames. Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Absorb small spills with sand or other noncombustible
absorbent material and place into containers for later disposal. Dike far
ahead of large spills for later disposal (*DOT 1984). Flood with water.
Rinse with sodium bicarbonate or lime solution (*CHRIS 1978).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Sore throat, fever, chills, difficulty in
breathing (*Patty 1963), pulmonary edema with frothy exudate (*Gosselin
1976), and severe skin and eye irritation (*Encyc Occupat Health and Safety
1983) have been reported.
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CAS Registry Number: 107-30-2
Page 4 of 4
CHLOROMETHYL METHYL ETHER
SECTION IX (continued)
Emergency and First Aid Procedures: MoVe victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes
(*DOT 1984).
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CAS Registry Number: 107-44-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SARIN
CAS Registry Number: 107-44-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 122) Phosphonofluoridic
Acid, Methyl-, Isopropyl Ester; GB; IMPF; Isopropoxymethylphosphoryl Fluoride;
Isopropyl Methanefluorophosphonate; Isopropyl Methylfluorophosphate;
Isopropyl-Methyl-Phosphoryl Fluoride; Methylphosphonofluoridic Acid Isopropyl
Ester; MFI; Phosphine Oxide, Fluoroisopropoxymethyl; Phosphoric Acid,
Methylfluoro-, Isopropyl Ester; Sarin II; T-144; T-2106; TL 1618; Trilone 46
Chemical Formula: C4H10FO2P
Molecular Weight: 140.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(human) 0.07 mg/liter (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 297°F, 147°C (Merck 1983, p. 1204)
Specific Gravity (H2O=1): 1.10 at 20°C/4°C (Merck 1983, p. 1204)
Vapor Pressure (mmHg): 2.9 at 25°C (U.S. Army 1975, p. 3-4)
Melting Point: -71°F, -57°C (Merck 1983, p. 1204)
Vapor Density (AIR=1): 4.86 (U.S. Army 1975, p. 3-4)
Evaporation Rate (Butyl acetate=l): About the same as water (U.S. Army
1975, p. 3-4)
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CAS Registry Number: 107-44-8
Page 2 of 4
SARIN
SECTION II (continued)
Solubility in Water: Miscible with and hydrolyzed by water (Merck 1983,
p. 1204)
Appearance and Odor: Liquid (Merck 1983, p. 1204). A colorless liquid
and vapor. Almost no odor in pure state (U.S. Army 1975, p. 3-3 to 3-4).
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (U.S. Army 1975, p. 3-4)
Skin: Yes (U.S. Army 1975, p. 3-4)
Ingestion: Yes (U.S. Army 1975, p. 3-4)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic; lethal
dose in humans may be as low as 0.01 mg/kg. Extremely active
cholinesterase inhibitor. Toxic effects similar to, but more severe than
those of parathion (Merck 1983, p. 1204). Death within 15 minutes after
fatal dose is absorbed (U.S. Army 1975, p. 3-4).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Non-flammable (U.S. Army 1975, p. 3-4)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with foam, carbon dioxide, and dry
chemical (Sax 1984, p. 1662) .
Special Fire Fighting Procedures: Protective clothing and respiratory
protection (U.S. Army 1975, p. 3-5).
Unusual Fire and Explosion Hazards: Non-flammable (U.S. Army 1975, p.
3-5)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (U.S. Army 1975, p. 3-4)
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CAS Registry Number: 107-44-8
Page 3 of 4
SARIN
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Slightly corrosive to steel (U.S.
Army 1975, p. 3-4). Hydrolyzed by water (Merck 1983, p. 1204).
Hazardous Decomposition or Byproducts: Acidic conditions produce hydrogen
fluoride; alkaline conditions produce isopropyl alcohol and polymers (U.S.
Army 1975, p. 3-4). When heated to decomposition or reacted with steam, it
emits very toxic fumes of fluorides and oxides of phosphorus (Sax 1984, p.
1662).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Quick-acting military chemical nerve agent (U.S. Army, p. 3-4). Chemical
warfare agent (Merck 1983, p. 1204).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Rapidly hydrolyzed by dilute aqueous sodium hydroxide or sodium carbonate
forming relatively non-toxic products. Water alone removes the fluorine
atom producing a non-toxic acid (Merck 1983, p. 1204). Decontaminants
include bleach slurry, dilute alkali, hot soapy water, steam and
ammonia (U.S. Army 1975, p. 3-4).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 107-44-8
Page 4 of 4
SARIN
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include difficulty in breathing,
drooling, excessive sweating, nausea, vomiting, cramps, involuntary
defecation and urination, twitching, jerking, staggering, headache,
confusion, drowsiness, coma, convulsion, dimness of vision, and pinpoint
pupils (U.S. Army 1975, p. 3-3).
Emergency and First Aid Procedures: Immediate decontamination of the
smallest drop is essential. Vapor penetrates the skin (U.S. Army 1975, p.
3-4). Toxic effects are similar to parathion (Sax 1984, p. 1662).
Treatment for parathion is as follows: move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 107-49-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TEPP
CAS Registry Number: 107-49-3
Synonyms: Pyrophosphoric Acid, Tetraethyl Ester (Dry Mixture);
Bis-O,O-Diethylphosphoric Anhydride; Bladan; Diphosphoric Acid, Tetraethyl
Ester; ENT 18,771; Ethyl Pyrophosphate [ET4P207]; Ethyl Pyrophosphate, Tetra-;
Fosvex; Grisol; Kept; Hesamite; Hexamite; Killax; Kilmite 40; Lethalaire G-52;
Lirohex; Mortopal; Nifos; Nifos T; Nifost; TEP; Terrasytam; Tetraethyl
Diphosphate; Tetraethylpyrophosphate; Tetrastigmine; Tetron; Tetron-100;
Vapotone; Vaptone
Chemical Formula: C8H20O7P2
Molecular Weight: 290.22
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (rat)
0.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 280°F, 138°C at 2.3 mm (*Merck 1983)
Specific Gravity (H2O=1): 1.185 at 20°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 0.00047 at 30°C (*Merck 1976)
Melting Point: 32°F, 0°C (NIOSH/OSHA 1978, p. 174)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (*Weast 1979); quickly hydrolyzed
(Merck 1983, p. 1317) "
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CAS Registry Number: 107-49-3
Page 2 of 4
TEPP
SECTION II (continued)
Appearance and Odor: Colorless liquid (*Spencer 1982); faint fruity odor
("CHRIS 1978). Technical product is a dark amber-colored liquid (*Worthing
1979).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 0.05 mg/ms (NIOSH/OSHA 1978, p. 174)
ACGIH TLV: TWA 0.004 ppm (0.05 mg/ms) (ACGIH 1986-87, p. 30)
IDLH: 10 mg/m8 (NIOSH/OSHA 1978, p. 174)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 175)
Skin: Yes (NIOSH/OSHA 1978, p. 175)
Ingestion: Yes (NIOSH/OSHA 1978, p. 175)
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. Probable oral lethal dose in humans is less than 5 mg/kg (a taste)
for a 150 Ib. person (*Gosselin 1976). A small drop in the eye may cause
death (*Clarke 1981). Small doses at frequent intervals are additive (*Sax
1979). Poisonings always develop at a rapid rate (*Gosselin 1976). It is
a cholinesterase inhibitor (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not combustible (NIOSH/OSHA 1978, p. 174)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing. Move container from fire area if you can do
it without risk. Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material (*DOT 1984).
Unusual Fire and Explosion Hazards: Extremely toxic fumes of unburned
material and phosphoric acid (*CHRIS 1978).
NFPA Flammability Rating: Not Found
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 107-49-3
Page 3 of 4
TEPP>
SECTION V - REACTIVITY DATA
Incompatibility (Materials to Avoid): Incompatible with strong oxidizers
(NIOSH/OSHA 1978, p. 174).
Hazardous Decomposition or Byproducts: Highly toxic gases and vapors of
unburned material and phosphoric acid are formed in fires (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION. VI -- USE INFORMATION
It is used as an insecticide and a rodenticide (*SRI; *Hawley 1981). No
rodenticide use registered in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of spills, stay upwind; stay out of low areas. Use water spray to
reduce vapors, but do not put water on spill area. Ventilate closed spaces
before entering them. Do not touch spilled material; stop leak if
possible. Take up spills with noncombustible absorbent material. For
large spills dike far ahead (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 107-49-3
Page 4 of 4
TEPP
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms are similar to those for
parathion, including nausea, vomiting, abdominal cramps, excessive
salivation, headache, giddiness, vertigo, weakness, runny nose, sensation
of tightness in the chest, blurring or dimness of vision, weakness and
twitching of muscles, confusion, difficulty in breathing, convulsions, and
coma (*Gosselin 1976).
Emergency and First Aid Procedures: Move victim to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. If contact with material occurs, flush .skin or eyes with running
water for at least 15 minutes. Remove and isolate contaminated clothing.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed. Keep victim under observation (*DOT 1984).
-------
CAS Registry Number: 108-05-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- VINYL ACETATE MONOMER
CAS Registry Number: 108-05-4
Synonyms: 1-Acetoxyethylene; Acetic Acid Ethenyl Ester; Acetic Acid Vinyl
Ester; Acetic Acid, Ethenyl Ester; Ethenyl Acetate; VAC; Vinyl A Monomer; Vinyl
Acetate HQ; Vyac; Zeset T
Chemical Formula: C4H6O2
Molecular Weight: 86.09
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 5,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 162-163°F, 72-73°C (*Merck 1976)
Specific Gravity (H2O=1): 0.932 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 83 at 20°C; 140 at 30°C (*Verschueren 1983)
Melting Point: -136°F, -93.2°C (*Weast 1979)
Vapor Density (AIR=1): 3.0 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g/50 mL at 20°C (*Merck 1983)
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CAS Registry Number: 108-05-4
Page 2 of 4
VINYL ACETATE MONOMER
SECTION II (continued)
Appearance and Odor: Colorless to white mobile liquid (unstable) or blue-green
(stable) (*Sax 1975; *Weast 1979). Sweet, pleasant, fruity
characteristic odor in small quantities ("CHRIS 1978) or a sour, sharp
smell (*Verschueren 1983).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 10 ppm (30 mg/m8); STEL 20 ppm (60 mg/ms) (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: NIOSH recommended air ceiling concentration:
15 mg/ms for 15 minutes (*NIOSH 1977-Present). Maximum Air Concentration
(USSR): 10 mg/m3 (Encyc Occupat Health and Safety 1983, p. 2260).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (Sax 1984, p. 85)
Ingestion: Yes (*Lefaux 1968)
Health Hazards (Acute, Delayed, and Chronic): Vinyl acetate has been
related to reproductive abnormalities (*Talakina 1977). It is a skin and
upper respiratory tract irritant (*ACGIH 1980) and a central nervous system
depressant (*Rumack 1975 to Present). Exposure caused gradual
deterioration of heart muscles (*Agaronyon 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 18°F, -8°C (CC) (*NFPA 1978); 0.5-0.9°C (TOC)
(*Kirk-Othmer 1978)
Flammable Limits:
LEL: 2.6% (*Encyc Occupat Health and Safety 1983)
UEL: 13.4% ("Encyc Occupat Health and Safety 1983)
Extinguishing Methods: Small fires: extinguish with dry chemical, carbon
dioxide, water spray, fog, or alcohol foam. Large fires: water spray,
fog, or alcohol foam (*DOT 1984).
Special Fire Fighting Procedures: Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing. Spray
cooling water on containers that are exposed to flames until well after the
fire is out. For massive fire in cargo area, use unmanned hose holder or
monitor nozzles; if this is impossible, withdraw from area and let fire
burn. Withdraw immediately in case of rising sound from venting safety
device or any discoloration of tank due to fire. Isolate for 1/2 mile
in all directions if tank car or truck is involved in fire
(DOT 1984, Guide 26).
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CAS Registry Number: 108-05-4
Page 3 of 4
VINYL ACETATE MONOMER
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid fumes (*Sax 1975). Highly dangerous when exposed to heat,
flames or oxidizers; explosion hazard with strong acids and strong
oxidizers (Sax 1984, p. 85).
NFPA Flammability Rating: 3
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1976)
Conditions to Avoid: Avoid light or any polymerizing initiator
(*Merck 1976, *Bretherick 1979).
Incompatibility (Materials to Avoid): Incompatible with alumina
(*Bretherick" 1979); oxidizing materials (*Sax 1975); 2-aminoethanol,
chlorosulf onic acid; ethyleneimine; 36% hydrochloric acid; 48.7%
hydrofluoric acid; 70% nitric acid; oleum; 96% sulfuric acid; ethylene
diamine; peroxides (*NFPA 1978); and silica gel (*Bretherick 1979).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
burns and emits acrid fumes (*Sax 1975).
Hazardous Polymerization: May Occur: Yes (*Kirk-Othmer 1978)
May Not Occur:
Conditions to Avoid: Polymerization can be initiated by organic and
inorganic peroxides; azo compounds; redox systems (including
organometallic components); light; and high energy radiation
(*Kirk-Othmer 1978).
SECTION VI - USE INFORMATION
Monomer for making poly (vinyl acetate) and vinyl acetate copolymers, which
are used in water based paints, adhesives, paper coatings, or nonwoven
binders and applications not requiring service at extreme temperatures
(*Kirk-Othmer 1978). In polymerized form it is used for plastic masses,
films, and lacquers (*Merck 1983). It is also used in the production of
emulsion paint ingredients, finishing and impregnation materials and glue
(*Encyc Occupat Health and Safety 1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid all skin and eye contact and inhalation (see Section III above).
Keep unnecessary people away and stay upwind. For spill or leaks shut
off ignition sources; no flares, smoking or flames in hazard area.
Use water spray to reduce vapors. Absorb spills with noncombustible
absorbent material (DOT 1984, Guide 26). :
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CAS Registry Number: 108-05-4
Page 4 of 4
VINYL ACETATE MONOMER
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
CPE GOOD/LIMITED*
PVC POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 108-05-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
VINYL ACETATE MONOMER
(108-05-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to white liquid.
Odor - Sweet, pleasant.
Commercial Form - Liquid in 1- to 5-gallon cans, 55-gallon steel drums, tank
trucks, and tank barges.
Uses - Manufacture of vinyl acetate, plastic, adhesives, paper coatings,
nonwoven binders, films, lacquers, water-based paints, glue, cosmetics, and
safety glass; chewing gum base; fumigant.
Materials to Avoid - Acids, alkali, oxidizers.
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including fire or sparks.
Other Names - Acetic acid, vinyl ester; ethenyl acetate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate,
diazepam, phenytoin, phenobarbital, morphine.
Signs and Symptoms of Acute Vinyl Acetate Monomer Exposure:
Vinyl acetate monomer may irritate the skin, eyes, and respiratory tract;
blisters may form. Inhalation of vapors may result in dizziness or
suffocation.
-------
EFATG
CAS Registry Number: 108-05-4
Page 2 of 3
VINYL ACETATE MONOMER
Emergency Life-Support Procedures:
Acute exposure to vinyl acetate monomer may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to vinyl acetate monomer.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to vinyl acetate monomer.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 108-05-4
Page 3 of 3
VINYL ACETATE MONOMER
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of vinyl acetate monomer is unknown or suspected to be greater
than. 30 minutes, do not induce vomiting and proceed to Step 4. Ipecac
should not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 108-23-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ISOPROPYL CHLOROFORMATE
CAS Registry Number: 108-23-6
Synonyms: Carbonochloride Acid, 1-Methylethyl Ester; Carbonochloridic Acid,
1-Methylethyl Ester; Chloroformic Acid Isopropyl Ester; Formic Acid, Chloro-,
Isopropyl Ester; Isopropyl Chlorocarbonate; Isopropyl Chloromethanoate
Chemical Formula: C4H7C1O2
Molecular Weight: 122.55
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 inhalation
(mouse) 1.5 mg/liter/hour (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 220°F, 104.6°C at 761 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.08 (*Patty 1963)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 4.2 (*Patty 1963)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Weast 1979)
Appearance and Odor: Colorless liquid (*Hawley 1977)
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CAS Registry Number: 108-23-6
Page 2 of 4
ISOPROPYL CHLOROFORMATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1657)
Skin: Yes (Sax 1984, p. 1657)
Ingestion: Yes (Sax 1979, p. 1657)
Health Hazards (Acute, Delayed, and Chronic): Acute: highly toxic by
inhalation, ingestion and skin absorption (Sax 1984, p. 1657). Delayed:
can produce delayed pulmonary edema (2-24 hours after exposure) similar to
that produced by phosgene (*Patty 1963; *Rumack 1975 to Present).
Inhalation of material may cause death or permanent injury (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 60.1°F, 15.6°C (*Clayton and Clayton
1981-1982)
Flammable Limits: Flammable; may be ignited by heat, sparks or flame (DOT
1984, Guide 29)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Keep unnecessary people away and isolate hazard
area. Stay upwind and keep out of low areas. Wear self-contained
(positive pressure if available) breathing apparatus and full protective
clothing. For small fires, use dry chemical, carbon dioxide, water spray
or foam. For large fires, use water spray, fog or foam. Do not get water
inside container. Cool containers exposed to flame with water until well
after fire is out. Withdraw immediately in case of rising sound from
venting safety device or any discoloration of tank due to fire (DOT 1984,
Guide 29).
Special Fire Fighting Procedures: Isolate for 1/2 mile in all directions
if tank car or truck is involved in fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: Extremely dangerous; this chemical
has exploded while stored in refrigerator (*Sax 1979). Vapor explosion
hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or
explosion hazard (DOT 1984, Guide 29).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 108-23-6
Page 3 of 4
ISOPROPYL CHLOROFORMATE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Patty 1963)
Stable:
Conditions to Avoid: Avoid phosgene (*Sax 1979)
Incompatibility (Materials to Avoid): Reacts violently with phosgene
(*Sax 1979).
Hazardous Decomposition or Byproducts: Like other chlorides (Sax 1984, p.
1657) when heated to decomposition or on contact with acids or acrid fumes,
they evolve highly toxic chloride fumes (Sax 1984, p. 672).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a chemical intermediate for free-radical polymerization initiators
and in organic synthesis (*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of spills or leaks, shut off ignition sources and keep away flares,
smoke or flames. Do not touch spilled material. Use water to reduce
vapors but do not get water inside containers. Take up small spills with
sand or other noncombustible absorbent material and place in containers
for later disposal. For large spills, dike far ahead of spill for
later disposal (DOT 1984, Guide 29).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Eye irritation, irritation of upper
respiratory tract and surface burns have been observed. Eye irritation may
persist after exposure ceases, and skin sensitization may occur (*Patty
1963). Inhalation exposures at elevated concentrations cause death by
immediate lung damage, lower concentrations cause difficult breathing,
collapse, and convulsions (Clayton and Clayton 1981-1982, p. 2390).
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CAS Registry Number: 108-23-6
Page 4 of 4
ISOPROPYL CHLOROFORMATE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air. Obtain
emergency medical care immediately. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes
(DOT 1984, Guide 29).
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CAS Registry Number: 108-91-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CYCLOHEXYLAMINE
CAS Registry Number: 108-91-8
Synonyms: Aminocyclohexane; Aminohexahydrobenzene; Benzenamine, Hexahydro-;
CHA; Cyclohexanamine; Hexahydroaniline; Hexahydrobenzenamine
Chemical Formula: C6H1SN
Molecular Weight: 99.17
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: Chemical does
not meet the toxicity criteria but because of its high production
volume and recognized toxicity it is considered a chemical of
concern.
TPQ: 10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 274.1°F, 134.5°C (*Merck 1983)
Specific Gravity (H2O=1): 0.8647 at 25°C/25°C (*Merck 1983)
Vapor Pressure (mmHg): Not Found
Melting Point: 0.1°F, -17.7°C (*Merck 1983)
Vapor Density (AIR=1): 3.42 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1983)
Appearance and Odor: A colorless to yellow liquid with a strong, fishy,
amine odor (*NFPA 197'8; *Merck 1983).
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CAS Registry Number: 108-91-8
Page 2 of 4
CYCLOHEXYLAMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 10 ppm (40 mg/m5) (ACGIH 1986-87, p. 15)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 298)
Skin: Yes (Hawley 1981, p. 298)
Ingestion: Yes (Hawley 1981, p. 298)
Health Hazards (Acute, Delayed, and Chronic): This is classified as very
toxic -- probable oral lethal dose is 50-500 mg/kg or between 1 teaspoon
and 1 ounce for a 70 kg (150 Ib.) person (*Gosselin 1976). It is
considered a nerve poison (*LeFaux 1968). This is a weak
methemoglobin-forming substance (*ACGIH 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 88°F, 31°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, alcohol foam or carbon dioxide;
water may be ineffective (*NFPA 1978).
Special Fire Fighting Procedures: Move container from fire area if you
can do it without risk. Stay away from ends of tanks. Cool containers
that are exposed to flames with water from the side until well after fire
is out. Withdraw immediately, in case of rising sound from venting safety
device or any discoloration of tank due to fire. Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Wear self-contained (positive pressure if available) breathing
apparatus and full protective clothing. Isolate for one-half mile in all
directions if tank car or truck is involved in fire (DOT 1984, Guide 68).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes (Sax 1984, p. 834). Vapor may travel a
considerable distance to source of ignition and flash back (*NFPA 1978).
Toxic oxides of nitrogen are produced during combustion (Student 1984, p.
162).
NFPA Flammability Rating: 3
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CAS Registry Number: 108-91-8
Page 3 of 4
CYCLOHEXYLAMINE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Physical damage, storage with oxidizing material
(*NFPA 1978).
Incompatibility (Materials to Avoid): Nitric acid; reacts vigorously with
oxiding materials (Sax 1984, p. 834).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in organic synthesis, manufacturing of pesticides, plasticizers,
emulsifying agents, dry-cleaning soaps, acid gas absorbents (*Merck 1983);
corrosion inhibitor in boiler water and oil fields; chemical intermediate
for rubber-processing chemicals, dyes, cyclamate artificial sweeteners
(non-U.S. use) and for herbicide; processing agent for nylon fiber
production (*SRI). Not registered as a pesticide in the U.S. (USEPA/
Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Shut off ignition sources; no flares,
smoking or flames in hazard area. Do not touch spilled material; stop
leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other non-combustible absorbent material
and place into containers for later disposal. Large spills: dike
far ahead of spill for later disposal (DOT 1984, Guide 68).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 108-91-8
Page 4 of 4
CYCLOHEXYLAMINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Neoprene POOR/LIMITED
Nitrile POOR/LIMITED
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Light-headedness, drowsiness, anxiety,
apprehension, nausea, slurred speech, vomiting, pupillary dilation, severe
skin irritation (*ACGIH 1980; *Clayton and Clayton 1981-82).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
68).
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CAS Registry Number: 108-95-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHENOL
CAS Registry Number: 108-95-2
Synonyms: Benzenol; Carbolic Acid; Hydroxybenzene; Izal; Monohydroxybenzene;
Monophenol; NCI-C50124; Oxybenzene; Phenic Acid; Phenyl Alcohol; Phenyl
Hydrate; Phenyl Hydroxide; Phenylic Acid; Phenylic Alcohol
Chemical Formula: C6H6O
Molecular Weight: 94.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mammal) 0.074 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 359.1°F, 181.75°C (*Weast 1979)
Specific Gravity (H2O=1): 1.0722 at 20/4°C (*Weast 1979)
Vapor Pressure (mmHg): 0.3513 at 25°C (*Sunshine 1969)
Melting Point: 109°F, 43°C (*Merck 1976)
Vapor Density (AIR=1): 3.24 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 93 g/liter at 25°C (*Morrison 1973)
Appearance and Odor: Colorless crystals or white crystalline mass (*Merck
1976), with aromatic, somewhat sickening sweet and acrid odor (*Clayton and
Clayton 1981-82). It is liquefied by mixing with about 8% water (Merck
1983, p. 1043).
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CAS Registry Number: 108-95-2
Page 2 of 4
PHENOL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 ppm (19 mg/m3) (NIOSH 1987, p. 188)
ACGIH TLV: TWA 5 ppm (19 mg/ms); STEL 10 ppm (38 mg/ms) (to be changed)
(ACGIH 1986-87, p. 26)
IDLH: 250 ppm (NIOSH 1987, p. 188)
Other Limits Recommended: NIOSH: 20 mg/ms (5.2 ppm) 10-hour TWA, ceiling
60 mg/ms (15.6 ppm)/15 minutes (NIOSH 1987, p.188)
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health
and Safety 1971)
Skin: Yes (*NFPA 1978)
Ingestion: Yes (*NFPA 1978)
Health Hazards (Acute, Delayed, and Chronic): Toxic hazard rating is very
toxic: probable oral lethal dose (human) is 50-500 mg/kg (*Gosselin 1976).
Ingestion of 1 gram has been lethal to humans (*Encyc Occupat Health and
Safety 1971). Lethal amounts may be absorbed through skin or inhaled
(*NFPA 1978). Industrial contact can cause chronic poisoning with kidney
and liver damage (*Merck 1976).
Medical Conditions Generally Aggravated by Exposure: Persons affected
with hepatic or kidney diseases are at a greater risk (*Clayton and Clayton
1981-82).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 79°C (CC) (*Sunshine 1969)
Flammable Limits:
LEL: 1.7% (*CHRIS 1978)
UEL: 8.6% (*CHRIS 1978)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam (alcohol); large fires: water spray, fog or foam; use water
spray to cool containers in fire area (*Environment Canada 1981).
Special Fire Fighting Procedures: Move container from fire area if it can
be done without risk; fight fire from maximum distance; dike fire control
water for later disposal, do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Flammable vapors when heated (*NFPA
1978). Runoff from fire control water may give off poisonous gases and
cause pollution (*DOT 1984). Mixtures of 9-10% phenol in air are explosive
(*Clayton and Clayton 1981-82).
NFPA Flammability Rating: 2
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CAS Registry Number: 108-95-2
Page 3 of 4
PHENOL
»
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Decomposes slowly on air contact (*Merck 1976).
Avoid contact with strong oxidizing agents ("CHRIS 1978).
Incompatibility (Materials to Avoid): Aluminum chloride/nitrobenzene
mixture, peroxodisulfuric acid, peroxomonosulfuric acid (*Bretherick 1979),
and strong oxidizing agents (*CHRIS 1978).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Disinfectant, antiseptic, bactericide (*Merck 1976). Chemical intermediate
for phenolic resins, medicinals, and many other chemicals; solvent for
petroleum refining (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Spills must be disposed of immediately by properly protected personnel; no
others should remain in area. Flush with flooding quantities of water,
then use caustic soda solution for neutralization (*NFPA 1978). Remove
and isolate contaminated clothing at the site (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED*
CPE POOR/LIMITED
Neoprene POOR/LIMITED
Nitrile POOR/MANY
PE GOOD/LIMITED
PVC POOR/MANY
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CAS Registry Number: 108-95-2
Page 4 of 4
PHENOL
SECTION VIII (continued)
Teflon GOOD/LIMITED
Viton POOR/LIMITED*
*Based on qualitative performance information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 108-95-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHENOL
(108-95-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless or white to pink crystalline mass.
Odor - Sickeningly sweet, acrid.
Commercial Forms - Liquid mixed with other components (mostly cresols), or
fused crystals in 25- and 55-gallon drums, tank cars, or tank trucks.
Uses - Chemical intermediate, analytical reagent, petroleum solvent,
disinfectant, antiseptic, preservative.
Materials to Avoid - Strong oxidizers.
Other Names - Carbolic acid, hydroxybenzene, Izal, phenic acid, phenyl alcohol,
phenyl hydroxide, phenylic acid, phenylic alcohol.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, polyethylene glycol 300 or 400, water,
milk, syrup of Ipecac, activated charcoal, saline cathartic or sorbitol, D5W,
normal saline, Ringer's lactate, castor oil, diazepam, phenytoin,
phenobarbital, 1% methylene blue.
Signs and Symptoms of Acute Phenol Exposure:
Signs and symptoms of acute exposure to phenol may be severe, and range from
tachycardia (rapid heart rate) and tachypnea (rapid respiratory rate) to
hypotension (low blood pressure), weak pulse, cardiac failure, pulmonary edema,
and respiratory arrest. Cardiac arrhythmias may be noted.
Weakness, headache, dizziness, tinnitus (ringing in the ears), delirium, and
shock are common. Seizures may often be followed by coma. Pallor, profuse
sweating, dilated pupils, and a profound drop in body temperature may occur.
Gastrointestinal effects may include nausea, abdominal pain, bloody vomitus,
and bloody diarrhea. Renai insufficiency may lead to hematuria (bloody urine).
Liver damage may also occur.
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EFATG
CAS Registry Number: 108-95-2
Page 2 of 3
PHENOL
Phenol is corrosive to the skin and mucous membranes. Contact may result in
severe and painful burns, which promptly become anesthetized (numb) to touch
and pain. Ulceration may follow.
Emergency Life-Support Procedures:
Acute exposure to phenol may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phenol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phenol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Remove phenol from skin with undiluted polyethylene glycol 300 or 400, if
available. If not available, use water. Follow polyethylene glycol wash
with a water wash.
6. Wash exposed skin areas for at least 15 minutes with large amounts of
water.
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EFATG
CAS Registry Number: 108-95-2
Page 3 of 3
PHENOL
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures,
8. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Immediately give the victims water or milk: children up to 1 year old,
125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or
3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given
only if victims are conscious and alert.
4. If a dilute (5% or less) solution has been ingested, vomiting may be
induced with syrup of Ipecac. DO NOT induce vomiting if concentration is
greater than 5% or unknown. If elapsed time since ingestion of phenol is
unknown or suspected to be greater than 30 minutes, do not induce vomiting
and proceed to Step 5. Ipecac should not be administered to children
under 6 months of age.
Warning: Ingestion of phenol may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are^ alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 5.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. Transport to a health care facility.
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CAS Registry Number: 108-98-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THIOPHENOL
CAS Registry Number: 108-98-5
Synonyms: Benzene, Mercapto-; Benzenethiol; Mercaptobenzene; Phenol, Thio-;
Phenyl Mercaptan; Phenylthiol
Chemical Formula: C6H6S
Molecular Weight: 110.17
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.126 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 334.9°F, 168.3°C (*Merck 1976)
Specific Gravity (H2O=1): 1.0728 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 1 at 18.6°C (Weast 1979, p. D-208)
Melting Point: 5.4°F, -14.8°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Merck 1976)
Appearance and Odor: Water-white liquid (*Hawley 1977); repulsive,
penetrating, garlic-like odor especially when impure (*Merck 1976).
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CAS Registry Number: 108-98-5
Page 2 of 4
THIOPHENOL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.5 ppm, 2 mg/ms (*ACGIH 1981)
IDLH: Not Found
Other Limits Recommended: Occupational exposure to benzenethiol
recommended standard: air ceiling concentration 0.5 mg/ms/15 minutes
(*NIOSH/RTECS 1985).
Routes of Entry: Inhalation: Yes (Sax 1984, p. 368)
Skin: Yes (Sax 1984, p. 368)
Ingestion: Yes (Sax 1984, p. 368)
Health Hazards (Acute, Delayed, and Chronic): Marked potential for
causing eye changes (*Encyc Occupat Health and Safety 1983). May cause
death (DASE 1980, p. 189)
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog or foam. Move container
from fire area if you can do so without risk. Spray cooling water on
containers that are exposed to flames until well after fire is out. Fight
fire from maximum distance. Dike fire control water for later disposal; do
not scatter the material (DOT 1984, Guide 57).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 57).
Unusual Fire and Explosion Hazards: When heated to decomposition or on
contact with acids, it emits toxic fumes of sulfur oxides (Sax 1984, p.
368). May be ignited by heat, sparks or flames. Container may explode in
heat of fire. Vapor explosion and poison hazard indoors, outdoors or in
sewers (DOT 1984, Guide 57).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 108-98-5
Page 3 of 4
THIOPHENOL
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes. Oxidizes in air (*Merck 1976).
Stable:
Conditions to Avoid: Contact with acids (Sax 1984, p. 368).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of sulfur oxides (Sax 1984, p. 368).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Pesticide (*Rumack 1975 to Present); intermediate for pesticides, alkyl
phenyl sulfides, polymers, and other materials (*SRI); pharmaceutical
synthesis (Hawley 1981, p. 1020); mosquito larvicide (Sax 1984, p. 368).
Not registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Shut off ignition sources;
no flares, smoking, or flames in hazard area. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other non-combustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal. Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them (DOT 1984, Guide 57).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 108-98-5
Page 4 of 4
THIOPHENOL
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 108-98-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
THIOPHENOL
(108-98-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Water-white liquid.
Odor - Penetrating, garliclike.
Uses - Manufacture of pesticides, Pharmaceuticals, polymers, and alkyl phenyl
sulfides; mosquito larvicide.
Other Names - Benzenethiol, mercaptobenzene, phenyl mercaptan.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, milk, normal saline, D5W,
Ringer's lactate, decadron.
Signs and Symptoms of Acute Thiopheno! Exposure:
Acute exposure to thiophenol may result in cough, difficulty in breathing,
irritation of the lungs, and pneumonia. Nausea, vomiting, and diarrhea are
often seen. Contact with thiophenol may result in irritation and redness,
pain, inflammation, and severe burns to the skin, eyes, and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to thiophenol may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
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EFATG
CAS Registry Number: 108-98-5
Page 2 of 3
THIOPHENOL
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to thiophenol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to thiophenol.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. THOROUGHLY wash exposed skin areas with water for at least 15 minutes.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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EFATG
CAS Registry Number: 108-98-5
Page 3 of 3
THIOPHENOL
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
6. Transport to a health care facility.
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CAS Registry Number: 109-61-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PROPYL CHLOROFORMATE
CAS Registry Number: 109-61-5
Synonyms: n-Propyl Chloroformate; Carbonochloridic Acid, Propyl Ester; Formic
Acid, Chloro-, Propyl Ester; Propyl Chlorocarbonate
Chemical Formula: C^HjClO^
Molecular Weight: 122.56
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 skin
(mouse) 10.0 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 237-241°F, 114-116°C (*Merck 1976)
Specific Gravity (H2O=1): 1.090 at 20 (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): 4.2 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Sax 1984, p. 2307)
Appearance and Odor: Colorless liquid (*Merck 1976)
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CAS Registry Number: 109-61-5
Page 2 of 4
PROPYL CHLOROFORMATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 19S4, p. 2307)
Skin: Yes (DOT 1984, Guide 28)
Ingestion: Yes (DOT 1984, Guide 28)
Health Hazards (Acute, Delayed, and Chronic): Strongly irritating to eyes
and mucous membranes (*Clayton and Clayton 1981-82). Poisonous; may be
fatal if inhaled, swallowed or absorbed through skin (DOT 1984, Guide 28).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -58°F, -50°C (*Clayton and Clayton 1981-82)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray and foam. Move container from fire area if you can do so without
risk. Dike fire control water for later disposal; do not scatter the
material. Spray cooling water on containers that are exposed to flames
until after fire is out. Withdraw immediately in case of rising sound from
venting safety device or any discoloration of tank due to fire (DOT 1984,
Guide 28).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
positive pressure breathing apparatus and special protective clothing.
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of chlorine containing compounds (Sax 1984, p. 2307).
Propyl chloroformate is a flammable/combustible material; it may be ignited
by heat, sparks or flames. Vapors may travel to a source of ignition and
flash back. Container may explode in heat or fire. Vapor explosion and
poison hazard indoors, outdoors or in sewers. Runoff to sewer may create
fire or explosion hazard. Runoff from fire control or dilution water may
cause pollution (DOT 1984, Guide 28).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 109-61-5
Page 3 of 4
PROPYL CHLOROFORMATE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Clayton and Clayton 1981-82)
Stable:
Conditions to Avoid: Decomposes spontaneously to form hydrochloric
acid and other products. Avoid moist air (*Clayton and Clayton
1981-82).
Incompatibility (Materials to Avoid): Gradually decomposed by water and
alcohol (Merck 1983, p. 1130)
Hazardous Decomposition or Byproducts: Decomposes and forms hydrochloric
acid (*Clayton and Clayton 1981-82).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Spill or leak: shut off ignition
sources; no flares, smoking or flames in hazard area. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 28).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Contact may cause burns to skin and eyes
(DOT 1984, Guide 28). Vapors strongly irritating to eyes and mucous
membranes (Merck 1983, p. 1130).
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CAS Registry Number: 109-61-5
Page 4 of 4
PROPYL CHLOROFORMATE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed; keep victim under observation (DOT 1984, Guide 28).
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CAS Registry Number: 109-77-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MALONONITRILE
CAS Registry Number: 109-77-3
Synonyms: Cyanoacetonitrile; Dicyanomethane; Malonic Acid Dinitrile; Malonic
Dinitrile; Malonicdinitrile; Malonodinitrile; Methane, Dicyano-; Methylene
Cyanide; Methylenedinitrile; Propanedinitrile; USAF A-4600
Chemical Formula: CSH2N2
Molecular Weight: 66.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDBO oral
(mouse) 19 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 424-426°F, 218-219°C (*Weast 1979)
Specific Gravity (H2O=1): 1.1910 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 90°F, 32°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 13 g/100 ml (*Patty 1963)
Appearance and Odor: Material is a colorless to white solid (*Sax 1979,
*Patty 1963)
-------
CAS Registry Number: 109-77-3
Page 2 of 4
MALONONITRILE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not found
ACGIH TLV: Not found
IDLH: Not found
Other Limits Recommended: Occupational exposure to nitriles recommended
standard -- TWA 8 mg/ms (*NIOSH/RTECS 1985).
Routes of Entry: Inhalation: Yes (*Patty 1963)
Skin: Yes (*Patty 1963)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Metabolized by body to
cyanide and thiocyanate; effects of inhalation of toxic fumes will be
related to cyanide (*Rumack 1975 to Present, *Patty 1963). Causes brain
and heart damage related to lack of cellular oxygen (*Doull 1980). It is
classified as extremely toxic. Probable oral lethal dose for humans is
5-50 mg/kg, or between 7 drops and 1 teaspoonful, for a 70 kg (150 Ib.)
person (Gosselin 1984, p. 11-215).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 266°F, 130°C (OC) (*Sax 1979)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Move container from fire area if you
can do it without risk. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition,
malononitrile emits highly toxic fumes (*Sax 1979). May polymerize
violently on prolonged heating (*Bretherick 1979).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Heat
-------
CAS Registry Number: 109-77-3
Page 3 of 4 '
MALONONITRILE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Highly toxic fumes (cyanide) when
heated (*Sax 1979).
Hazardous Polymerization: May Occur: Yes (*Bretherick 1979)
May Not Occur:
Conditions to Avoid: Prolonged heating at 130°C or contact with
strong bases at lower temperatures (*Bretherick 1979).
SECTION VI - USE INFORMATION
It is used in organic synthesis, and as a leaching agent for gold (*Hawley
1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid all skin contact, inhalation, and ingestion (see Section III above).
Take up small spills with sand or other noncombustible material. Dike
far ahead of large spills for later disposal. Do not touch spilled
material; stop leak if you can do so without risk. Stay upwind and out
of low areas. Isolate area and deny entry (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: See cyanides (*Rumack 1975 to Present).
Symptoms of cyanide poisoning include rapid and irregular breathing,
anxiety, confusion, odor of bitter almonds (on breath or vomitus), nausea,
vomiting (if oral exposure), irregular heart beat, a feeling of tightness
in the chest, bright pink coloration of the skin, unconsciousness followed
by convulsions, involuntary urination and defecation, paralysis and
respiratory arrest (heart will beat after breathing stops) (Gosselin 1984,
p. III-126-127).
Emergency and First Aid Procedures: See cyanides. Get emergency medical
treatment immediately. If the victim stops breathing before emergency
medical treatment is available, give artificial respiration or oxygen, but
avoid mouth to mouth respiration; also avoid contact with contaminated
-------
CAS Registry Number: 109-77-3
Page 4 of 4
MALONONITRILE
SECTION IX (continued)
skin. If there is exposure through skin contact, wash immediately with
soap and water. Exposed eyes should be flushed with copious amounts of
water for at least 15 minutes (*Rumack 1975 to Present).
-------
CAS Registry Number: 110-00-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FURAN
CAS Registry Number: 110-00-9
Synonyms: l,4-Epoxy-l,3-Butadiene; Divinylene Oxide; Furfuran; NCI-C56202;
Oxacyclopentadiene; Oxole; Tetrole; Axole
Chemical Formula: C4H40
Molecular Weight: 68.08
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.12 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 90°F, 32°C at 758 mmHg (*Merck 1983)
Specific Gravity (H2O=1): 0.9371 at 19.4°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: -123°F, -86°C (*Sax 1979)
Vapor Density (AIR=1): 2.3 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Merck 1976); 10 g/liter at 25°C
(Verschueren 1983, p. 686)
Appearance and Odor: Clear colorless liquid turning brown upon standing
(Hawley 1981, p. 483)
-------
CAS Registry Number: 110-00-9
Page 2 of 4
FURAN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Exposure concentration limit: 10 ppm (*Sax
1979).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): The vapors are narcotic
(Merck 1983, p. 613). Acute exposure to furan by inhalation may involve
both reversible and irreversible changes. Acute exposure by ingestion or
skin absorption, as well as chronic exposure, are associated with high
toxicity (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Less than 32°F, less than 0°C (CC)
(*NFPA 1978)
Flammable Limits:
LEL: 2.3% (*NFPA 1978)
UEL: 14.3% (*NFPA 1978)
Extinguishing Methods: Water may be ineffective (*NFPA 1978). Small
fires: dry chemical, carbon dioxide, water spray, or alcohol foam. Large
fires: water spray, fog, or alcohol foam (DOT 1984, Guide 26).
Special Fire Fighting Procedures: Move container from fire area if this
can be accomplished without risk. Spray cooling water on containers that
are exposed to flames until well after fire is out. For massive fires in
cargo area, use unmanned hose holder or monitor nozzles; if this is
impossible withdraw from area and let fire burn. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire. Isolate for 1/2 mile in all directions if a tank car or
truck is involved (DOT 1984, Guide 26).
Unusual Fire and Explosion Hazards: Very dangerous, upon exposure to heat
or flame. It may form unstable peroxides on exposure to air. Contact with
acids can initiate a violent, heat producing reaction (*Sax 1979).
NFPA Flammability Rating: 4
-------
CAS Registry Number: 110-00-9
Page 3 of 4
FURAN
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Sax 1979)
Stable:
Conditions to Avoid: Upon standing in air, it may form unstable
peroxides (*Sax 1979).
Incompatibility (Materials to Avoid): Acids, oxidizing agents (*Sax
1979).
Hazardous Decomposition or Byproducts: Formation of unstable peroxides
upon standing in air (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chemical intermediate for tetrahydrofuran (*SRI); formation of lacquers,
solvent for resins (*Browning 1965); organic synthesis, especially for
pyrrole, thiophene (*Hawley 1981).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Avoid
breathing vapors. Keep upwind. Do not handle broken packages without
protective equipment. Wash away any material which may have contacted the
body with copious amounts of water or soap and water. Shut off ignition
sources; no flares, smoking, or flames in hazard area. Stop leak if you can
do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill
for later disposal (Student 1984, p. 259; DOT 1984, Guide 26). The exposure
concentration limit of 10 ppm together with the low boiling point of furan
requires that adequate ventilation be provided in areas handling this
chemical. Contact with liquid must be avoided since this chemical can be
absorbed through the skin. Thorough washing with soap and water followed
by prolonged rinsing should be done immediately after accidental contact
(Sax 1984, p. 1462).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 110-00-9
Page 4 of 4
FURAN
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Butyl/Neoprene POOR/LIMITED*
PVC POOR/MANY
Viton POOR/LIMITED
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Vapors are a central nervous system
depressant (*Merck 1976). Irritation and burning eyes and skin, dizziness,
suffocation (DOT 1984, Guide 26).
Emergency and First Aid Procedures: Move victim to fresh air; if not
breathing give artificial respiration or if breathing is difficult give
oxygen. In case of contact with the material, immediately flush eyes with
running water for at least 15 minutes. Wash skin with soap and water.
Remove and isolate contaminated clothing and shoes at the site (DOT 1984,
Guide 26).
-------
CAS Registry Number: 110-57-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRANS-1,4-DICHLOROBUTENE
CAS Registry Number: 110-57-6
Synonyms: l,4-Dichloro-trans-2-Butene; l,4-Dichloro-2-Butene;
1,4-Dichlorobutene; l,4-Dichlorobutene-2 (trans); 2-Butene, 1,4-Dichloro-,
(E)-; 2-Butene, 1,4-Dichloro-, trans-; 2-Butylene Dichloride;
Trans-1,4-Dichloro-2-Butene
Chemical Formula: C4H6C12
Molecular Weight: 125.00
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.44 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 312°F, 155.5°C at 758 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.183 at 25/4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 34-37°F, 1-3°C (*Weast 1979)
Vapor Density (AIR=1): 4 (Weiss 1980, p. 322)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble in water (*Weast 1979)
Appearance and Odor: Colorless liquid with a distinct odor (*IARC
1972-85).
-------
CAS Registry Number: 110-57-6
Page 2 of 4
TRANS-1,4-DICHLOROBUTENE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*IARC 1972-85)
Skin: Yes (*Grant 1974)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific —
Dichlorobutene) Liquid and vapors from the material are highly corrosive
and may damage skin, eyes, lungs, and internal organs (*IARC 1972-85).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: 1.5% (Weiss 1980, p. 330)
UEL: 4% (Weiss 1980, p. 330)
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
spray or foam. For large fires, use water spray, fog, or foam (DOT 1984,
Guide 29).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and full protective clothing. Move containers from fire area if
you can do so without risk. Spray containers with cooling water until well
after fire is out. Isolate for one-half mile in all directions if tank car
or truck is involved in a fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: The material will burn, though it may
require some effort to ignite (Student 1981, p. 184). Fire produces
irritating and poisonous gases (DOT 1984, Guide 29). When heated to
decomposition, it emits toxic fumes of chlorine-containing compounds (Sax
1984, p. 583).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 322)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 110-57-6
Page 3 of 4
TRANS-1,4-DICHLOROBUTENE
SECTION V (continued)
Hazardous Decomposition or Byproducts: When, heated to decomposition, it
emits toxic fumes of chlorine-containing compounds (Sax 1984, p. 583).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is a chemical intermediate for hexamethylenediamine and chloroprene
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area. Stay upwind; keep out
of low areas. Shut off ignition sources. Do not touch spilled material.
Use water spray to reduce vapors, but do not get water inside containers.
For small spills, absorb with sand or other non-combustible absorbent
material. For large spills, dike far ahead of spill for later disposal
(DOT 1984, Guide 29).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED**
Butyl/Neoprene POOR/LIMITED**
CPE POOR/LIMITED**
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 110-57-6
Page 4 of 4
TRANS-1.4-DICHLOROBUTENE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Respiratory distress and burns to skin
and eyes (DOT 1984, Guide 29). Inhalation of vapor irritates nose and
throat. Contact with eyes causes intense irritation and tears. Contact of
liquid with skin causes severe blistering. Ingestion causes severe
irritation of mouth and stomach (Weiss 1980, p. 322).
Emergency and First Aid Procedures: Move victim to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. Remove and isolate contaminated clothing. In case of contact,
immediately flush skin and eyes with running water for 15 minutes. Keep
victim quiet and maintain normal body temperature (DOT 1984, Guide 29).
-------
CAS Registry Number: 110-89-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PIPERIDINE
CAS Registry Number: 110-89-4
Synonyms: Azacyclohexane; Cyclopentimine; Cypentil; Hexahydropyridine;
Hexazane; Pentamethyleneimine; Pentamethylenimine; Pyridine, Hexahydro-
Chemical Formula: C5HUN
Molecular Weight: 85.15
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mammal) 22.4 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 223°F, 106°C (*Merck 1976)
Specific Gravity (H2O=1): 0.8622 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 40 at 29.2°C (*Patty 1963)
Melting Point: 19°F, -7°C (*Merck 1976), 16°F, -9°C (Weast 1980, p.
C-441)
Vapor Density (AIR=1): 3.0 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in all proportions (*Weast 1979)
Appearance and Odor: Piperidine is a clear colorless liquid with an
amine-like odor (Sax 1984, p. 2236). A pepper-like odor has also been
reported (Hawley 1981, p. 819).
-------
CAS Registry Number: 110-89-4
Page 2 of 4
PIPERIDINE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and
Safety 1971)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
Ingestion: Yes (*Encyc Occupat Health and
Safety 1971)
Health Hazards (Acute, Delayed, and Chronic): Strong local irritant and
may cause permanent injury after short exposure to small amounts.
Ingestion may involve both irreversible and reversible changes (*Sax 1975).
30 to 60 mg/kg may cause symptoms in humans (Clayton and Clayton 1981, pp.
2689-90).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 61°F (no method given) (*Patty 1963); 37.4°F
(no method given) (Sax 1984, p. 2236)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or alcohol foam. Large fires: water spray, fog, or alcohol foam.
Move container from fire area if you can do it without risk. Do not get
water inside container. Cool containers that are exposed to flames with
water from the side until well after fire is out. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire (DOT 1984, Guide 29).
Special Fire Fighting Procedures: Keep unnecesary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low area. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing. Isolate for 1/2 mile in all directions if tank
car or truck is involved in fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: Piperidine evolves explosive
concentrations of vapor at normal room temperatures (*Encyc Occupat Health
and Safety 1971). When heated to decomposition, it emits highly toxic
fumes of nitrogen oxides (*Sax 1979). Dangerous, when exposed to heat,
flame, or oxidizers (Sax 1984, p. 2236).
NFPA Flammability Rating: 3
-------
CAS Registry Number: 110-89-4
Page 3 of 4
PIPERIDINE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: It evolves explosive concentrations of vapor at
normal room temperatures (*Encyc Occupat Health and Safety 1971). Keep
away from igniting sources and heat (*NFPA 1978).
Incompatibility (Materials to Avoid): Avoid 1-Perchlorylpiperidine (Sax
1984, p. 2236) and oxidizing materials (*Sax 1979). Piperidine is a
reactive compound and forms complexes with the salts of heavy metals (Merck
1983, p. 1077).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of nitrogen oxides (Sax 1984, p. 2236).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Solvent and intermediate; curing agent for rubber and epoxy resins;
catalyst for condensation reactions; ingredient in oils and fuels;
complexing agent (Hawley 1981, p. 818); manufacture of local anesthetics,
analgesics, Pharmaceuticals, wetting agents, and germicides (*Encyc Occupat
Health and Safety 1971); synthetic flavoring (*Fenaroli 1975). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III). Shut off ignition sources; no flares,
smoking, or flames in hazard area. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors;
do not get water inside container. Small spills: absorb with sand or
other noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 29).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 110-89-4
Page 4 of 4
PIPERIDINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED*
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms upon oral administration include
weakness, nausea, vomiting, salivation, labored respiration, muscular
paralysis, and asphyxiation (Clayton and Clayton 1981, pp. 2689-90).
Redness, pain, and burns occur upon contact with skin. Corrosive effects
seen when contact is made with the eyes. Sore throat, coughing, labored
breathing, and dizziness occur after inhalation (DASE 1980, p. 757).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
29).
-------
CAS Registry Number: 111-44-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DICHLOROETHYL ETHER
CAS Registry Number: 111-44-4
Synonyms: Bis(2-Chloroethyl) Ether; l,l'-Oxybis(2-Chloroethane);
l,5-Dichloro-3-Oxapentane; l-Chloro-2-(beta-Chloroethoxy)Ethane;
2,2'-Dichloroethyl Ether; 2,2'-Dichlorodiethyl Ether; 2,2'-Dichlorethyl Ether;
2-Chloroethyl Ether; beta.beta'-Dichlorodiethyl Ether; beta,beta'-Dichloroethyl
Ether; beta,beta-Dichlorodiethyl Ether; bis(2-Chloroethyl)Ether;
bis(beta-Chloroethyl) Ether; bis(Chloro-2-Ethyl) Oxide; Chlorex; Chloroethyl
Ether; Clorex; DCEE; Di(2-Chloroethyl) Ether; Di(beta-Chloroethyl)Ether;
Dichloroether; Dichloroethyl Oxide; ENT 4,504; Ether, bis(2-Chloroethyl);
sym-Dichloroethyl Ether
Chemical Formula: C4H8C12O
Molecular Weight: 143.02
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.33 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 352°F, 178°C (*Merck 1976)
Specific Gravity (H2O=1): 1.22 at 20/20°C (*Merck 1976)
Vapor Pressure (mmHg): 0.7 at 20°C (*Sax 1979)
Melting Point: -58°F, -50°C (Merck 1983, p. 445)
Vapor Density (AIR=1): 4.93 (*Browning 1965)
Evaporation Rate (ButyJ acetate=l): Not Found
-------
CAS Registry Number: 111-44-4
Page 2 of 4
DICHLOROETHYL ETHER
SECTION II (continued)
Solubility in Water: Slightly soluble in hot water (*Weast 1979)
Appearance and Odor: Colorless, clear liquid with pungent (*Merck 1976)
or nauseating (*ACGIH 1980) or sweet, pleasant odor (*CHRIS 1978). At the
vapor concentration necessary to cause respiratory tract damage, the odor
is easily detectable and usually intolerable (*Patty 1963)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 15 ppm (90 mg/ms) (NIOSH 1987, p. 100)
ACGIH TLV: TWA 5 ppm (30 mg/m8); STEL 10 ppm (60 mg/m8) (skin) (*ACGIH
1982)
IDLH: 250 ppm (NIOSH/OSHA 1978, p. 82)
Other Limits Recommended: Maximum air concentration (USSR) 2 mg/m3 (Encyc
Occupat Health and Safety 1983, p. 122)
Routes of Entry: Inhalation: Yes (*Browning 1965)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is very
toxic; the probable oral lethal dose is 50-500 mg/kg, or between 1
teaspoonful and 1 ounce for a 150 pound person (*Gosselin 1976). It can be
a central nervous system depressant in high concentrations. It is
extremely irritating to the eyes, nose, and respiratory passages (*Browning
1965). It can penetrate the skin to cause serious and even fatal poisoning
(*Encyc Occupat Health and Safety 1971). Poisonous; may be fatal if
inhaled, swallowed or absorbed through skin (DOT 1984, Guide 57).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 180°F, 82°C (OC); 131°F, 55°C (CC) (Weiss
1980, p. 325)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water, foam, mist, fog, spray, or dry chemical
(*Sax 1979). Use water in flooding quantities as fog (Student 1981, p.
185). Small fires: dry chemical, carbon dioxide, water spray, or foam.
Large fires: water spray, fog, or foam. Move container from fire area if
you can do so without risk. Spray cooling water on containers that are
exposed to flames until well after fire is out. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 57).
-------
CAS Registry Number: 111-44-4
Page 3 of 4
DICHLOROETHYL ETHER
SECTION IV (continued)
Special Fire Fighting Procedures: Wear full protective clothing (*NFPA
1978). Do not extinguish fire unless flow can be stopped. Cool all
affected containers with flooding quantities of water. Apply water from as
far a distance as possible (Student 1981, p. 185).
Unusual Fire and Explosion Hazards: May form phosgene or hydrogen
chloride in fires (*CHRIS 1978). There is danger of explosion when ethers
are heated or exposed to flames or sparks. Ethers tend to form peroxides;
when ethers containing peroxides are heated, they can detonate (*Sax 1979).
May be ignited by heat, sparks, or flames. Container may explode in heat
of fire. Vapor explosion and poison hazard indoors, outdoors or in sewers
(DOT 1984, Guide 57).
NFPA Flammability Rating: 2
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 325)
Conditions to Avoid: Ethers tend to form peroxides upon standing.
Heating peroxide-containing ethers can cause detonation (*Sax 1979).
Incompatibility (Materials to Avoid): Reacts vigorously with oleum and
chlorosulfonic acid (*Sax 1979).
Hazardous Decomposition or Byproducts: Decomposes in the presence of
moisture to form hydrochloric acid (*Martin 1974). Emits toxic fumes when
heated to decomposition (*Sax 1979); may form phosgene or hydrochloric acid
in fires (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a chemical intermediate for organic compounds and
polymers (*SRI), in the treatment of textiles (*Merck 1976) and in dry
cleaning (*Hawley 1977), as a pesticide (*NRC 1977; *Farm Chemicals
Handbook 1977), as an anesthetic (*IARC 1972-1985), and for various other
applications.
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Remove all ignition sources. Ventilate area of spill or leak. Do not
allow this material to enter a confined space, such as a sewer, because of
the possibility of an explosion. Absorb spills in vermiculite, dry sand,
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CAS Registry Number: 111-44-4
Page 4 of 4
DICHLOROETHYL ETHER
SECTION VII (continued)
earth, or similar material (*NIOSH/OSHA 1981). Keep material out of water
sources and sewers. Build dikes to contain flow as necessary. Use water
spray to knock down vapors (Student 1981, p. 185). Spill or leak: shut
off ignition sources; no flares, smoking or flames in hazard area. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
(DOT 1984, Guide 57).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
CPE GOOD/LIMITED
Teflon GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: At concentrations above 500 ppm,
.coughing, retching, and vomiting may occur (*Browning 1965), as well as
profuse tearing (*Grant 1974). There can be irritation at lower
concentrations (*Browning 1965). Contact may cause burns to skin and eyes
(DOT 1984, Guide 57).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 57).
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CAS Registry Number: 111-69-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ADIPONITRILE
CAS Registry Number: 111-69-3
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 287): Adipic Acid
Dinitrile; Adipic Acid Nitrile; Adipodinitrile; 1,4-Dicyanobutane;
Hexanedinitrile; Hexanedioic Acid, Dinitrile; Tetramethylene Cyanide
Chemical Formula: C6H8N2
Molecular Weight: 108.16
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: Chemical
does not meet the toxicity criteria but because of its high
production volume and recognized toxicity it is considered a
chemical of concern.
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 563°F, 295°C (Sax 1984, p. 143)
Specific Gravity (H2O=1): 0.965 at 20/4°C (Sax 1984, p. 143)
Vapor Pressure (mmHg): Not Found
Melting Point: 36.1°F, 2.3°C (Sax 1984, p. 143)
Vapor Density (AIR=1): 3.73 (Sax 1984, p. 143)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Hawley 1981, p. 21)
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CAS Registry Number: 111-69-3
Page 2 of 4
ADIPONITRILE
SECTION II (continued)
Appearance and Odor: Water white liquid, practically odorless (Sax 1984,
p. 143).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Occupational exposure to nitriles, recommended
standard: TWA 18 mg/m3 (NIOSH/RTECS 1983, Volume 1, p. 287).
Routes of Entry: Inhalation: Yes (Sax 1984, p. 143)
Skin: Yes (DOT 1984, Guide 55)
Ingestion: Yes (Sax 1984, p. 143)
Health Hazards (Acute, Delayed, and Chronic): This material is toxic by
ingestion and inhalation (Hawley 1981, p. 21). It produces disturbances of
the respiration and circulation, irritation of the stomach and intestine,
and loss of weight (Sax 1984, p. 143). It is irritating to skin and eyes
(Weiss 1980, p. 60).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 199.4°F (OC) (Sax 1984, p. 143)
Flammable Limits:
LEL: 1.0% at 200°C (Weiss 1980, p. 60)
UEL: Not Found
Extinguishing Methods: Dry chemical, carbon dioxide, water spray, fog or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear chemical protective suit with
self-contained breathing apparatus. Cool exposed containers with water
(Weiss 1980, p. 60).
Unusual Fire and Explosion Hazards: Combustion products may contain
hydrocyanic acid (HCN) (Sax 1984, p. 143). Vapor may explode if ignited in
an enclosed area (Weiss 1980, p. 60).
NFPA Flammability Rating: 2
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 60)
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CAS Registry Number: 111-69-3
Page 3 of 4
ADIPONITRILE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Oxidizing material (Sax 1984, p.
143).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes (Sax 1984, p. 143).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 60)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an intermediate in the manufacture of nylon and in
organic synthesis (Hawley 1981, p. 21).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors. Small spills: take up with sand or other
non-combustible absorbent materal and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 111-69-3
Page 4 of 4
ADIPONITRILE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 111-69-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
ADIPONITRILE
(111-69-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Adiponitrile toxicity can occur via ingestion, dermal/eye contact, or
inhalation. IMMEDIATELY begin administering 100% oxygen and RUSH victims to a
health care facility.
Substance Characteristics:
Pure Forms - Water white to light yellow liquid, or needles at temperatures
below 2 degrees C (36 degrees F).
Odor - None.
Uses - Chemical intermediate, solvent, extractant for aromatic hydrocarbons,
manufacture of nylon, organic synthesis.
Caution: Avoid sources of extreme heat or ignition including sparks or fire.
Adiponitrile will liberate toxic gases when heated to decomposition. Vapors
may explode if ignited in an enclosed area.
Other Names - Adipic acid dinitrile; adipodinitrile; 1,4-dicyanobutane;
hexanedinitrile; tetramethylene cyanide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulf ate), diazepam,
phenytoin.
Signs and Symptoms of Acute Adiponitrile Exposure:
Warning: Effects may be delayed. Caution is advised. Vital signs should be
monitored closely.
Signs and symptoms of acute exposure to adiponitrile may include tightness of
the chest and tachypnea (rapid respiratory rate). Tachycardia (rapid heart
rate), hypotension (low blqp.d pressure), and cyanosis (blue tint to skin and
mucous membranes) may also occur. Victims may experience headache, weakness,
-------
EFATG
CAS Registry Number: 111-69-3
Page 2 of 3
ADIPONITRILE
dizziness, difficulty in standing, dilated pupils, confusion, and seizures.
Vomiting has been reported. Adiponitrile may irritate or burn the skin, eyes,
and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to adiponitrile may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure .
to adiponitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with adiponitrile-contaminated
persons or their gastric contents can result in self-poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to adiponitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with adiponitrile-contaminated
persons or their gastric contents can result in self-poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
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EFATG
CAS Registry Number: 111-69-3
Page 3 of 3
ADIPONITRILE
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for .
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with adiponitr-He-contaminated
persons or their gastric contents can result in self-poisoning.
2. RUSH to a health care facility!
3. DO NOT induce vomiting. Ipecac is not recommended for ingestion of
adiponitrile.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 115-21-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRICHLOROETHYLSILANE
CAS Registry Number: 115-21-9
Synonyms: Silane, Ethyltrichloro-; Ethyl Silicon Trichloride;
Ethyltrichlorosilane; Silane, Ethyl(Trichloro)-; Silane, Trichloroethyl-;
Silicane, Trichloroethyl-; Trichloroethylsilicane; Trichloroethylsilicon
Chemical Formula: C2H6ClsSi
Molecular Weight: 163.51
SECTION I « REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCBO inhalation
(mouse) 0.0003 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 208°F, 97.9°C (*Weast 1979)
Specific Gravity (H2O=1): 1.2381 at 20°C/4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: -158°F, -105.6°C (*Weast 1979)
Vapor Density (AIR=1): 5.6 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (*Weast 1979)
Appearance and Odor: Trichloroethylsilane is a colorless liquid (*Hawley
1981).
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CAS Registry Number: 115-21-9
Page 2 of 3
TRICHLOROETHYLSILANE
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Vapor and liquid cause
burns. Do not inhale or expose eyes to vapor. Vapor may damage eyes even
if not immediately painful (NFPA 1984, pp. 49-89).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 72°F, 22.2°C (OC) (*Sax 1979)
Flammable Limits: May be ignited under almost all normal temperature
conditions (*NFPA 1978)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Caution: reacts with water to produce heat and
toxic and corrosive fumes -- see Section IV below.) Use dry chemical,
alcohol foam, or carbon dioxide; water may be ineffective, but water should
be used to keep fire-exposed containers cool. If a leak or spill has not
ignited, use water spray to disperse the vapors and to protect men
attempting to stop a leak. Water spray may be used to flush spills away
from exposure and to dilute spills to non-flammable mixtures (*NFPA 1978).
Special Fire Fighting Procedures: Enter fire areas with extreme care.
Full protective clothing must be worn including self-contained breathing
apparatus, rubber gloves, boots, and bands around arms, legs, and waist.
No skin surface should be exposed (*NFPA 1978). Isolate for 1/2 mile in
all directions if tank car or truck is involved in fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Trichloroethylsilane may form
explosive mixtures with air (*Hawley 1981). Its vapors are heavier than
air and may travel a considerable distance to a source of ignition and
flash back (*NFPA 1978).
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Sax 1979)
Stable:
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CAS Registry Number: 115-21-9
Page 3 of 3
TRICHLOROETHYLSILANE
SECTION V (continued)
Conditions to Avoid: Decomposing heat (*Sax 1979)
Incompatibility (Materials to Avoid): Will react with water or steam to
produce heat and toxic and corrosive fumes. Will react vigorously with
oxidizing materials (*Sax 1979).
Hazardous Decomposition or Byproducts: Toxic and corrosive fumes
including phosgene when heated to decomposition (*Sax 1979); hydrochloric
acid in presence of water (*Hawley 1981).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Chemical intermediate for silicones (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors or contact with eyes or skin (see Section III above).
Shut off ignition sources; no flares, flames, or smoking. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapor but do not get water inside container. Small spills:
take up with sand or other noncombustible absorbent material and
containerize. Large spills: dike ahead of spill for later disposal
(*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 115-21-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
TRICHLOROETHYLSILANE
(115-21-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, biting.
Commercial Form - Liquid in 1-gallon bottles (in steel containers) or 55-gallon
drums.
Use - Chemical intermediate for silicone products.
Materials to Avoid - Oxidizers, water (except for use in emergency life
support).
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. In the presence of water, trichloroethylsilane
liberates hydrochloric acid.
Other Name - Ethyltrichlorosilane, trichloroethylsilicane..
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Trichloroethylsilane Exposure:
Signs and symptoms of acute ingestion of trichloroethylsilane may be severe,
and include increased salivation, intense thirst, difficulty swallowing,
chills, pain, and shock. Oral, esophageal, and stomach burns are common.
Vomitus generally has a coffee-ground appearance. The potential for
circulatory collapse is high following ingestion of trichloroethylsilane.
Acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea
(shortness of breath), respiratory tract irritation, and chest pain. Bleeding
of nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema,
chronic bronchitis, and pneumonia may also occur. Renal toxicity has been
observed in animals.
-------
EFATG
CAS Registry Number: 115-21-9
Page 2 of 3
TRICHLOROETHYLSILANE
If the eyes have come in contact with trichloroethylsilane, then irritation,
pain (may be delayed in the case of vapor exposure), swelling, corneal erosion,
and blindness may result. Severe burns, pain, shock, and dermatitis (red,
inflamed skin) generally follow dermal exposure.
Emergency Life-Support Procedures:
Acute exposure to trichloroethylsilane may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to trichloroethylsilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to trichloroethylsilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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EFATG
CAS Registry Number: 115-21-9
Page 3 of 3
TRICHLOROETHYLSILANE
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Victims should not attempt to
swallow this water.
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
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CAS Registry Number: 115-26-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIMEFOX
CAS Registry Number: 115-26-4
Synonyms: Phosphorodiamidic Fluoride, Tetramethyl-; BFP; BFPO;
bis(Dimethylamido)Phosphoryl Fluoride; N,N,N',N'- Tetramethylphosphorodiamidic
Fluoride; Dimefox; Tetramethylphosphorodiamidic Fluoride;
bis(Dimethylamido)Fluorophosphate; bis(Dimethylamino)Fluorophosphate;
Bisdimethylaminofluorophosphine Oxide; CR 409; DIFO; DMF; Fluophosphoric acid
Di(Dimethylamide); Hanane; Pestox 14; Pestox IV; Pestox XIV; Phosphine Oxide,
bis(Dimethylamino)Fluoro-; Phosphorodiamidic Fluoride, Tetramethyl-; S-14;
T-2002; Terra-sytam; Terrasytum; Tetrasytam; Tetramethyldiamidophosphoric
Fluoride; TL 792; Wacker S 14/10
Chemical Formula: C4H12FN2OP
Molecular Weight: 154.13
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(rat) 1.0 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 187°F, 86°C at 15 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.115 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 0.36 at 25°C (*Martin 1974)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
-T
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 115-26-4
Page 2 of 4
DIMEFOX
SECTION II (continued)
Solubility in Water: Freely soluble (*Merck 1976)
Appearance and Odor: Colorless liquid (*Martin 1974) with a fishy odor
(*Merck 1976)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Martin 1974)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose (human) is 5-50 mg/kg, or 7 drops to 1
teaspoonful for a 150-lb. person. Death may occur from respiratory arrest
(*Gosselin 1976). Hazards of vapor toxicity are high (*Martin 1974).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Insecticide, Liquid, Poisonous,
n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Insecticide, Liquid,
Poisonous, n.o.s.) Stay upwind; keep out of low areas. Wear positive
pressure breathing apparatus and special protective clothing. Ventilate
closed spaces before entering them. Move container from fire area if you
can do so without risk. Dike fire control water for later disposal; do not
scatter the material {DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Highly toxic fumes are given off upon
decomposition with heat (*Sax 1975). (Non-Specific — Insecticide, Liquid,
Poisonous, n.o.s.) Container may explode in heat of fire (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 115-26-4
Page 3 of 4
DIMEFOX
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Sunshine 1969)
Conditions to Avoid: Decomposing heat (*Sax 1975); contact with
chlorine (*Sunshine 1969).
Incompatibility (Materials to Avoid): Decomposes rapidly in the presence
of chlorine. Oxidizes slowly in strong oxidizing agents (*Sunshine 1969).
Hazardous Decomposition or Byproducts: Highly toxic fumes are given off
when material is heated to decomposition (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an insecticide; it is neither produced nor used in
the U.S. (*SRI). Not registered as a pesticide in the U.S. (USEPA/
Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). (Non-Specific -- Insecticide,
Liquid, Poisonous, n.o.s.) Do not touch spilled material; stop leak if you
can do so without risk. Use water spray to reduce vapors. Small
spills: absorb with sand or other noncombustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 115-26-4
Page 4 of 4
DIMEFOX
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include headache, blurred
vision, nausea, cramps, difficulty in breathing, slurring of speech, and
excessive salivation (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Insecticide, Liquid,
Poisonous, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from the skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 115-29-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ENDOSULFAN
CAS Registry Number: 115-29-7
Synonyms: 5-Norbornene-2,3-Dimethanol, 1,4,5,6,7,7-Hexachloro-, Cyclic
Sulfite; l,2,3,4,7,7-Hexachlorobicyclo[2.2.1]Hepten-5,6-Bioxymethylenesulfite;
l,2,3,4,7,7-Hexachlorobicyclo-[2.2.1]-Hepten-5,6-Bisoxymethylene Sulfite;
l,2,3,4,7,7-Hexachlorobicyclo[2.2.1]-2-Heptene-5,6-Bisoxymethylene Sulfite;
1,4,5,6,7,7-Hexachloro-5-Norbornene-2,3-Dimethanol Cyclic Sulfite;
1,4,5,6,7,7-Hexachloro-8,9,10-Trinorborn-5-en-2,3-ylenedimethyl Sulphite;
6,7,8,9,10,10-Hexachloro-1,5,5 A,6,9,9 A-Hexahydro-6,9-Methano-2,4,3-
Benzo[e]dioxathiepin-3-Oxide; 6,9-Methano-2,4,3-Benzodioxathiepin,
6,7,8,9,10,10-Hexachloro-l,5,5A,6,9,9A-Hexahydro-, 3-Oxide; alpha,
beta-1,2,3,4,7,7-Hexachlorobicy clo[2.2.1 ]-2-Heptene-5,6-Bisoxymethylene
Sulfite; AS 4314; Benzoepin; Beosit; BIO 5,462; Chlorthiepin; Crisulfan;
Cyclodan; Devisulphan; Endocel; Endosol; Endosulphan; Ensure; ENT 23,979; FMC
5462; Hexachlorohexahydromethano-2,4,3-Benzodioxathiepin-3-Oxide; Hildan; HOE
2,671; Insectophene; Kop-Thiodan; Malix; NCI C00566; NIA 5462; Niagara 5,462;
QMS 570; Sulfurous Acid, Cyclic Ester with l,4,5,6,7,7-Hexachloro-5-
Norbornene-2,3-Dimethanol; Thifor; Thimul; Thiodan; Thiofor; Thiomul Thionex;
Thiosulfan; Thiosulfan Tionel; Thiotox [Insecticide]; Tionex; Tiovel; 6,7,8,9
10,10-Hexachloro-1,5,5a,6,9,9a-Hexahydro-6,9-Methano-2,4,3-Benzodioxathiepin-
3-Oxide
Chemical Formula: C9H6C16OSS
Molecular Weight: 406.95
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCBO inhalation
(rat) 0.08 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS (Continued)
Physical State: Solid
Boiling Point: Not Found
-------
CAS Registry Number: 115-29-7
Page 2 of 4
ENDOSULFAN
SECTION II (continued)
Specific Gravity (H2O=1): 1.745 at 20°C (Farm Chemicals Handbook 1984, p.
C-92)
Vapor Pressure (mmHg): 0.00001 at 77°F, 25°C (*Worthing 1979)
Melting Point: a isomer 228.7°F, 109.2°C; b isomer 415.9°F, 213.3°C (Farm
Chemicals Handbook 1984, p. C-92). Mixture 158-212°F, 70-100°C (Buchel
1983, p. 47; Hayes 1982, p. 252)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (Merck 1983, p. 516)
Appearance and Odor: Brown crystals (*Merck 1983); colorless crystals
(*Spencer 1982); smells like sulfur dioxide (Hayes 1982, p. 252)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/ms (skin) (ACGIH 1986-87, p. 18)
IDLH: Not Found
Other Limits Recommended: Maximum air concentration (USSR) 0.1 mg/ms
(Encyc Occupat Health and Safety 1983, p. 1634).
Routes of Entry: Inhalation: Yes (Hawley 1984, p. 410)
Skin: Yes (Sax 1984, p. 377)
Ingestion: Yes (Sax 1984, p. 377)
Health Hazards (Acute, Delayed, and Chronic): It is very toxic. The
probable oral lethal dose is 50 to 500 mg/kg, or 1 teaspoonful to 1 ounce
for a 150 Ib. person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish fire using agent suitable for type of
surrounding fire. (Material itself does not burn or burns with
difficulty.) Use water in flooding quantities as fog. Use alcohol foam,
carbon dioxide or dry chemical (Student 1981, p. 220).
-------
CAS Registry Number: 115-29-7
Page 3 of 4
ENDOSULFAN
SECTION IV (continued)
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Container may explode in heat of
fire. Fire or run off from fire control water may release irritating or
poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*White-Stevens 1971)
Conditions to Avoid: Slowly oxidizes in air (*White-Stevens 1971).
Do not store at temperature below 20°F (Farm Chemicals Handbook 1984,
p. C-92).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material is used as an insecticide for vegetable crops, fruits, and
nuts (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of spills, stay upwind; stay out of low areas. Use water spray to
reduce vapors. Ventilate closed spaces before entering them. Do not
touch spilled material; stop leak if you can do it without risk. Small
spills: take up with sand or other noncombustible absorbent material and
place into containers for later disposal. Small dry spills: with clean
shovel place material into clean, dry container and cover; move containers
from spill area. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
-------
CAS Registry Number: 115-29-7
Page 4 of 4
ENDOSULFAN
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 115-29-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
ENDOSULFAN
(115-29-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless crystals.
Odor - Pungent, resembles sulfur dioxide.
Commercial Forms - Brown crystals, wettable powder, dust, granules, or in
combination with dimethoate and parathion-methyl.
Use - Pesticide.
Materials to Avoid - Alkali, water (except for use in emergency life support).
Other Names - Benzoepin; Beosit; Chlorthiepin; Crisulfan; Cyclodan;
Devisulphan; Endosol; Ensure; Hildan; Insectophene; Malix; 5-norbornene-2,3-
dimethanol, 1,4,5,6,7,7-hexachlorocyclic sulfite; Thiodan; Thimul; Thionex;
Thiotox; Tionex.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, alcohol, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's
lactate, diazepam, phenytoin, phenobarbital, thiopental, succinylcholine,
cholestyramine.
Signs and Symptoms of Acute Endosulfan Exposure:
Ingestion of endosulfan may result in nausea, vomiting, and diarrhea.
Dizziness, agitation, nervousness, tremor, incoordination, and convulsions may
also occur. Central nervous system depression may terminate in respiratory
failure. Contact with endosulfan may irritate or burn the skin, eyes, and
mucous membranes.
-------
EFATG
CAS Registry Number: 115-29-7
Page 2 of 3
ENDOSULFAN
Emergency Life-Support Procedures:
Acute exposure to endosulfan may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to endosulfan.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to endosulfan.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times. An initial soap and water wash
should be followed by an alcohol wash. The third wash should again be
with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 115-29-7
Page 3 of 3
ENDOSULFAN
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of endosulfan is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of endosulfan may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 115-90-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ FENSULFOTHION
CAS Registry Number: 115-90-2
Synonyms: Phosphorothioic Acid, O,O-Diethyl O-(p-(Methysulfinyl)Phenyl)
Ester; Agricur; B 25141; Bay 25141; Bayer 25141; Bayer S767; Chemagro 25141;
Daconit; Dasanit; Dazanit; Desanit; Diethyl p-Methylsulfinylphenyl
Thiophosphate; DMSP; ENT 24,945; O,O-Diethyl O-(4-(Methylsulfinyl)Phenyl)
Phosphorothioate; O,O-Diethyl O-(p-(Methylsulfinyl)Phenyl) Phosphorothioate;
Phenol, p-(Methylsulfinyl)-, O-Ester With O,O-Diethyl Phosphorothioate;
Phosphorothioic Acid, O,O-Diethyl-O-(4-(Methylsulfinyl)Phenyl) Ester; S 767;
Terracur P; VUAGT; VUAGT 108; VUAGT 96
Chemical Formula: CUH17O4PS2
Molecular Weight: 308.35
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II « PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 280-286°F, 138-141°C at 0.01 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.202 (*Spencer 1973)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (B*tyl acetate=l): Not Found
-------
CAS Registry Number: 115-90-2
Page 2 of 4
FENSULFOTHION
SECTION II (continued)
Solubility in Water: 1.54 g/liter (*Worthing 1979)
Appearance and Odor: Oily yellow liquid (*Worthing 1979); brown liquid
(*Spencer 1973)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/m3 (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific -- Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Ingestion: Yes (Non-Specific -- Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): It displays cholinesterase
inhibiting properties (*ACGIH 1980). Death results primarily from
respiratory arrest stemming from failure of the respiratory center,
paralysis of respiratory muscles and intense bronchoconstriction (*Gosselin
1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray,
fog or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific ~ Organophosphorus
Pesticide, Liquid, n.o.s.) Wear positive pressure breathing apparatus and
special protective clothing. Move container from fire area. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) This material may burn but may not ignite
readily. Containers may explode in heat of fire (DOT 1984, Guide 55).
-------
CAS Registry Number: 115-90-2
Page 3 of 4
FENSULFOTHION
SECTION IV (continued)
When heated highly toxic fumes of phosphorus and sulfur oxides are emitted
(*Sax 1979).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Menzie 1969)
Conditions to Avoid: Hydrolyzes in alkali, isomerizes in air (*Menzie
1969).
Incompatibility (Materials to Avoid): Incompatible with alkali chemicals
(*Menzie 1969).
Hazardous Decomposition or Byproducts: Sulfur oxides and phosphorous
oxides are formed when heated to decomposition (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an insecticide, nematocide (*SRI), and mosquito
larvicide (*Spencer 1973).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific ~ Organophosphorus Pesticide, Liquid, n.o.s.) Keep
unnecessary people away; stay upwind. Do not touch spilled material; stop
leak if possible. Use water spray to reduce vapors. Take up with
noncombustible absorbent material. For large spills, dike far ahead of
spill (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 115-90-2
Page 4 of 4
FENSULFOTHION
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This material may cause nausea, vomiting,
abdominal cramps, diarrhea, headache, giddiness, vertigo, weakness, lack of
muscle control, tearing, slurring of speech, difficult breathing,
convulsions, excessive salivation, tightness in chest, and death from
respiratory arrest (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with the material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 116-06-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ALDICARB
CAS Registry Number: 116-06-3
Synonyms: Propionaldehyde, 2-Methyl-2-(Methylthio)-, O-(Methyl-
carbamoyl)Oxime; 2-Methyl-2-(Methylthio)Propanal, O-((Methylamino)Carbonyl)
Oxime; 2-Methyl-2-(Methylthio)Propionaldehyde O-(Methylcarbamoyl)Oxime;
Aldecarb; Carbamic Acid, Methyl-, O-((2- Methyl-2-(Methylthio)Propylidene)
Amino) Derivative; Carbamyl; Carbanolate; ENT 27,093; NCI-C08640; OMS 771;
Propanal, 2-Methyl-2-(Methylthio)-, O-((Methylamino)Carbonyl)Oxime;
Propionaldehyde, 2-Methyl-2-(Methylthio)-, O-(Methylcarbamoyl)Oxime; UC 21149;
Union Carbide 21149; Union Carbide UC-21149; Temik TSK; Sulfone aldoxycarb;
Temic; Ambush; Propanal, 2-Methyl-2-(Methylthio)-, O-((Methylamino)Carbonyl)
Oxime; Temic; Temik; Temik 10 G; Temik G 10
Chemical Formula: C7H14N2O2S
Molecular Weight: 190.23
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 0.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O»1): 1.1950 at 25°C (*Farm Chemicals Handbook 1983)
Vapor Pressure (mmHg): Less than 0.5 at 20°C (*Sunshine 1969)
Melting Point: 210-214°F, 99-101°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 116-06-3
Page 2 of 3
ALDICARB
SECTION II (continued)
Solubility in Water: 6 g/liter at 25°C (*Merck 1983)
Appearance and Odor: White crystals, slightly sulfurous odor (*Spencer
1982); commercial formulations are granular (*Farm Chemicals Handbook 1985)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Doull 1980)
Ingestion: Yes (*Doull 1980)
Health Hazards (Acute, Delayed, and Chronic): Aldicarb is a carbamate
pesticide (Hayes 1981, p. 447). This material is super toxic; the probable
oral lethal dose for humans is less than 5 mg/kg, or a taste (less than 7
drops) for a 150-lb. person (*Gosselin 1976); it is extremely toxic by both
oral and dermal routes (*Doull 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamate Pesticide, Solid) Some
of these materials may burn but none of them ignite readily. Small fires:
dry chemical, carbon dioxide, water spray, or foam. Large fires: water
spray, fog or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Carbamate Pesticide,
Solid) Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (*Sax 1984).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 116-06-3
Page 3 of 3
ALDICARB
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NIH 1979)
Conditions to Avoid: Unstable in alkali; poor stability at 122°F,
50°C (*Sunshine 1969).
Incompatibility (Materials to Avoid): Incompatible with highly alkaline
substances (*Farm Chemicals Handbook 1983).
Hazardous Decomposition or Byproducts: When heated, aldicarb emits very
toxic fumes of nitrogen oxides and sulfur oxides (*Sax 1984).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material is used as an insecticide, acaricide, and nematocide (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Carbamate Pesticide, solid) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 116-06-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
ALDICARB
(116-06-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystals.
Odor - Slightly sulfurous.
Commercial Form - 5 to 15% active ingredient in granular form (technical grade
is 99+% pure).
Use - Pesticide.
Caution: Avoid sources of heat including fire. Aldicarb will liberate toxic
nitrogen and sulfur oxide gases when heated.
Other Names - Carbamyl; Carbanolate; propionaldehyde, 2-methyl-2-(methylthio)-,
O-(methylcarbamoyl)oxime; Temik; Union Carbide 21149.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, diazepam, phenytoin.
Signs and Symptoms of Acute Aldicarb Exposure:
Acute exposure to aldicarb usually leads to a cholinergic crisis, with signs
and symptoms that may include increased salivation, lacrimation (tearing),
perspiration, and spontaneous defecation and urination. Pinpoint pupils,
blurred vision, tremor, muscle twitching, shortness of breath, mental
confusion, convulsions, and coma may also occur. Gastrointestinal effects
include nausea, vomiting, diarrhea, and abdominal pain. Bradycardia (slow
heart rate) occurs frequently.
-------
EFATG
CAS Registry Number: 116-06-3
Page 2 of 3
ALDICARB
Emergency Life-Support Procedures:
Acute exposure to aldicarb may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to aldicarb.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an .antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to aldicarb.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 116-06-3
Page 3 of 3
ALDICARB
f
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of aldicarb is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of aldicarb may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 119-38-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ISOPROPYLMETHYLPYRAZOLYL DIMETHYLCARBAMATE
CAS Registry Number: 119-38-0
Synonyms: Carbamic Acid, Dimethyl-, l-Isopropyl-3-Methylpyrazol-5-yl Ester;
1 -Isopropyl-3-Methyl-5-Pyrazolyl Dimethylcarbamate; 5-Methyl-2-
Isopropyl-3-Pyrazolyl Dimethylcarbamate; Carbamic Acid, Dimethyl-, 1-Isopropyl-
3-Methylpyrazol-5-yl Ester; Carbamic Acid, Dimethyl-, 3-Methyl-l-(l-
Methylethyl)-lH-Pyrazol-5-yl Ester; Dimethyl-5-(l-Isopropyl-3-Methyl-
PyrazolyI)-Carbamate; Dimethylcarbamic Acid l-Isopropyl-3-Methylpyrazol-5-yl
Ester; Dimethylcarbamic Acid 3-Methyl-l-(l-Methylethyl)-lH-Pyrazol-5-yl Ester;
ENT 19,060; G 23611; Primin; Pyrazol-5-ol, l-Isopropyl-3-Methyl-,
Dimethylcarbamate; Saolan; Isolan
Chemical Formula: C10H17N3O2
Molecular Weight: 211.27
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(rat) 5.6 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 217°F, 103°C at 0.7 mm (*Sax 1979)
Specific Gravity (H2O=1): 1.07 at 20°C (*Sax 1979)
Vapor Pressure (mmHg): 0.001 at 20°C (*Sunshine 1969)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
-1?
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 119-38-0
Page 2 of 4
ISOPROPYLMETHYLPYRAZOLYL DIMETHYLCARBAMATE
SECTION II (continued)
Solubility in Water: Miscible in water (*Hawley 1977)
Appearance and Odor: Colorless liquid (Hayes 1982, p. 454)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Gosselin 1984, p. 11-306)
Skin: Yes (Sax 1984, p. 1170)
Ingestion: Yes (Sax 1984, p. 1170)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely toxic. Probable oral lethal dose in humans is 5-50 mg/kg or
between 7 drops and 1 teaspoonful for a 150-lb. person (*Gosselin 1976). A
cholinesterase inhibitor; although it is not an organic phosphate, it
resembles that group in action (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use methods for liquid carbamate pesticides (Hayes
1982, p. 454). Small fires: dry chemical, carbon dioxide, water spray, or
foam. Large fires: water spray, fog, or foam. Move container from fire
area if you can do it without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: As with other liquid carbamate
pesticides (Hayes 1982, p. 454), keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1170).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 119-38-0
Page 3 of 4
ISOPROPYLMETHYLPYRAZOLYL DIMETHYLCARBAMATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1170).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Systemic aphicide used in Europe (Buchel 1983, p. 128); insecticide (Merck
1983, p. 744). Currently of little commercial interest (*Worthing 1979).
Not registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Treat as a liquid carbamate
pesticide (Hayes 1982, p. 454). Do not touch spilled material; stop leak
if you can do it without risk. Use water spray to reduce vapors. Small
spills: take up with sand or other noncombustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death due to respiratory
arrest. Symptoms include cool extremities; trembling; fixed pinpoint
pupils; nausea; vomiting; slight bluing of skin; lips and nailbeds;
tearing; diarrhea; excessive salivation; sweating; slurring of speech;
jerky movements; loss of bladder control; convulsions; coma and death
(*Gosselin 1976, Gosselin 1984, p. 11-306).
-------
CAS Registry Number: 119-38-0
Page 4 of 4
ISOPROPYLMETHYLPYRAZOLYL DIMETHYLCARBAMATE
SECTION IX (continued)
Emergency and First Aid Procedures: A liquid carbamate pesticide (Hayes
1982, p. 454). Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 122-14-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FENITROTHION
CAS Registry Number: 122-14-5
Synonyms: 8057HC; 80557HC; AC 47,300; Accothion; Aceothion; Agrothion;
Akotion; Bay 41831; Bayer 41831; Bayer S 5660; CL 47300; CP 47114; Cyfen;
Cytel; ENT 25,715; Falithion; Fentrothione; Folithion; m-Cresol, 4-Nitro-,
O-Ester with O,O-Dimethyl Phosphorothioate; MEP (Pesticide); Metathio E-50;
Metathion; Metathione; Metathionine; Metathionine E50; Metation; Methathion;
Methylnitrophos; Nitrophos; Novathion; Nuvanol; O,O-Dimethyl O-(3-Methyl)
Phosphorothioate; O,O-Dimethyl O-(3-Methyl-4-Nitrophenyl) Thiophosphate;
O,O-Dimethyl O-(4-Nitro-3-Methylphenyl)Thiophosphate; O,O-Dimethyl
O-4-Nitro-m-Tolyl Phosphorothioate; Oleosumifene; OMS 43; Ovadofos;
Phenitrothion; Phosphorothioic Acid, O,O-Dimethyl O-(3-Methyl-4-Nitrophenyl)
Ester; Phosphorothioic Acid, O.O-Dimethyl O-(4-Nitro-m-Tolyl) Ester; S 112A; S
5660; S-1102A; Sumithian; Sumithion
Chemical Formula: C9H12NO5PS
Molecular Weight: 277.25
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.378 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 244°F, 118°C at 0.05 mmHg (*Merck 1976)
Specific Gravity (H2O=1): 1.32 at 25/4°C (*Martin 1974)
Vapor Pressure (mmHg): 0.000006 at 20°C (*Martin 1974)
Melting Point: Not Fownd
-------
CAS Registry Number: 122-14-5
Page 2 of 4
FENITROTHION
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (*Merck 1976)
Appearance and Odor: Brownish-yellow oil (*Martin 1974; *Merck 1976)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 1174)
Ingestion: Yes (Sax 1984, p. 1174)
Health Hazards (Acute, Delayed, and Chronic): This compound is an
organophosphate insecticide. It is a highly toxic cholinesterase inhibitor
(Hawley 1981, p. 452) that acts on the nervous system (Doull 1980, p. 367).
Does not cause delayed neurotoxicity and contact produces little
irritation (Hayes 1982, p. 365).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is an organophosphate insecticide
(Encyc Occupat Health and Safety 1983, p. 1623). Small fires: dry
chemical, carbon dioxide, water spray, or foam. Large fires: water spray,
fog or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphate
Pesticide n.o.s.) Move containers from fire area if you can do so without
risk. Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 122-14-5
Page 3 of 4
FENITROTHION
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, for 2 years if stored at 20-25°C (Hayes 1982,
p. 365)
Conditions to Avoid: Unstable in alkaline media. Do not store above
40°C (Hayes 1982, p. 365).
Incompatibility (Materials to Avoid): Unstable in alkaline media (Hayes
1982, p. 365)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of nitrogen, phosphorus and sulfur (Sax
1984,'p. 1J74). Decomposition at 100-140°C produces a mixture of
organophosphorus polymers (*Menzie 1969).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is a selective acaricide (*Martin 1974) and a contact and stomach
insecticide (*Spencer 1973). Used to control chewing and sucking insects
on rice, orchard fruits, vegetables, cereals, cotton and forest. Also
protects against flies, mosquitoes, and cockroaches (Farm Chemicals
Handbook 1984, p. C-101).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphate Pesticide n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 122-14-5
Page 4 of 4
FENITROTHION
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea is often the first symptom,
followed by vomiting; abdominal cramps; diarrhea; excessive salivation;
headache; giddiness; dizziness; weakness; tightness in the chest; loss of
, muscle coordination; slurring of speech, muscle twitching (particularly the
tongue and eyelid); respiratory difficulty; blurring or dimness of vision;
pinpoint pupils; profound weakness; mental confusion; disorientation and
drowsiness (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphate
Pesticide n.o.s) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature (DOT 1984, Guide 55).
-------
CAS Registry Number: 123-31-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDROQUINONE
CAS Registry Number: 123-31-9
Synonyms: 1,4-Benzenediol; 1,4-Dihydroxybenzene; 4-Hydroxyphenol;
Alpha-Hydroquinone; Arctuvin; Benzohydroquinone; Benzoquinol; Beta-Quinol;
Black and White Bleaching Cream; Diak 5; Dihydroxybenzene; Eldopaque; Eldoquin;
HE 5; Hydroquinol; Hydroquinole; NCI-C55834; p-Benzenediol; p-Dihydroxybenzene;
p-Dioxobenzene; p-Hydroquinone; p-Hydroxyphenol; para-Dihydroxybenzene;
para-Dioxybenzene; para-Hydroquinone; Phiaquin; Quinol; Tecquinol; Tenox HQ;
Tequinol; USAF EK-356
Chemical Formula: C6H6O2
Molecular Weight: 110.11
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: Chemical does not
meet the toxicity criteria but because of its high production volume
and recognized toxicity it is considered a chemical of concern.
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 545-549°F, 285-287°C (*Merck 1976)
Specific Gravity (H2O=1): 1.332 at 15°C (Merck 1983, p. 699)
Vapor Pressure (mmHg): 4 at 150°C (*Clayton and Clayton 1981-82)
Melting Point: 338-340°F, 170-171°C (*Merck 1976)
Vapor Density (AIR=1): 3.81 (*Sax 1975)
Evaporation Rate (Butyl acetate=l): Not Found
j»
Solubility in Water: Soluble in 14 parts water (*Merck 1976)
-------
CAS Registry Number: 123-31-9
Page 2 of 4
HYDROQUINONE
SECTION II (continued)
Appearance and Odor: Colorless (*Sax 1975) to white crystals (*IARC
1972-1985).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 2 mg/m3 (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 2 mg/m3 (ACGIH 1986-87, p. 21)
IDLH: 200 mg/m3 (NIOSH/OSHA 1978, p. 114)
Other Limits Recommended: NIOSH: 2 mg/m3 15-minute ceiling (NIOSH 1987,
p. 140)
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*IARC 1972-1985)
Ingestion: Yes (*IARC 1972-1985)
Health Hazards (Acute, Delayed, and Chronic): This material is very
toxic; the probable oral lethal dose for humans is 50-500 mg/kg, or between
1 teaspoon and 1 ounce for a 150 Ib. person. It is irritating but not
corrosive. Fatal human doses have ranged from 5-12 grams, but 300-500 mg
have been ingested daily for 3-5 months without ill effects (*Gosselin
1976). Death is apparently initiated by respiratory failure or anoxia
(*Encyc Occupat Health and Safety 1971).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 329°F (CC) (*Sax 1975)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires use dry chemical, carbon dioxide,
water spray or foam. Move container from fire area if you can do so
without risk (*DOT 1984). This compound is a slight fire or explosion
hazard (*NFPA 1978).
Special Fire Fighting Procedures: Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Dust cloud may explode if ignited in
an enclosed area (*CHRIS 1978).
NFPA Flammability Rating: 1
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CAS Registry Number: 123-31-9
Page 3 of 4
HYDROQUINONE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Oxidizes in air (Merck 1983, p. 699)
Incompatibility (Materials to Avoid): It can react with oxidizing
materials (*Sax 1975) and is rapidly oxidized in the presence of alkaline
materials (*Merck 1976).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Photographic developer and reducer; antioxidant for fats and oils;
polymerization inhibitor; stabilizer in paints, varnishes, motor fuels, and
oils; in human medicine for skin blemishes; chemical intermediate for dyes;
reagent in phosphate analysis (*SRI; *Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Do not touch spilled material; stop leak
if you can do it without risk. Small spills: take up with sand or other
non-combustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area.
Large spills: dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Neoprene GOOD/LIMITED*
Nitrile GOOD/LIMITED*
PE GOOD/LIMITED :
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CAS Registry Number: 123-31-9
Page 4 of 4
HYDROQUINONE
SECTION VIII (continued)
PVC GOOD/LIMITED
Viton GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 123-31-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDROQUINONE
(123-31-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to white crystals.
Commercial Form - Light tan to light gray crystals in glass bottles, paper
sacks, or fiber drums.
Uses - Photographic developer and reducer, antioxidant for fats and oils,
polymerization inhibitor, reagent in phosphate analysis, paint and varnish
stabilizer, component in fuel mixtures.
Materials to Avoid - Alkali, oxidizers.
Other Names - Arctuvin, 1,4-benzenediol, Diak 5, 1,4-dihydroxybenzene, para-
dihydroxybenzene, Eldoquin, 4-hydroxyphenol, Phiaquin, Quinol, Tecquinol,
Tenox HQ.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's
lactate, diazepam, phenytoin, phenobarbital, methylene blue, castor oil.
Signs and Symptoms of-Acute Hydroquinone Exposure:
Signs and symptoms of acute exposure to hydroquinone may be severe and include
dyspnea (shortness of breath), a sense of suffocation, increased respiratory
rate, and respiratory failure. Pallor (paleness of the skin), cyanosis (blue
tint to skin and mucous membranes), and cardiovascular collapse may occur.
Neurologic effects include headache, tinnitus (ringing in the ears),
dizziness, delirium, muscle twitching, tremor, and convulsions. Nausea,
vomiting, and the production of green to brown-green urine may also occur.
Hydroquinone may be irritating and corrosive to the skin, eyes, and mucous
membranes. Jaundice (yellow tint to skin) may be noticed.
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EFATG
CAS Registry Number: 123-31-9
Page 2 of 3
HYDROQUINONE
Emergency Life-Support Procedures:
Acute exposure to hydroquinone may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydroquinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydroquinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 123-31-9
Page 3 of 3
HYDROQUINONE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen.
2. IMMEDIATELY give the victims water or milk: children up to 1 year
old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL
(6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should
be given only if victims are conscious and alert.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of hydroquinone is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac
should not be administered to children under 6 months of age.
Warning: Ingestion of hydroquinone may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 5.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (I oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. Transport to a health care facility.
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CAS Registry Number: 123-73-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CROTONALDEHYDE, (E)-
CAS Registry Number: 123-73-9
Synonyms: (E)-Crotonaldehyde; 2-Butenal (trans); 2-Butenal, (E)-; beta-Methyl
Acrolein; Crotenaldehyde; Crotonal; Crotonaldehyde; Crotonic Aldehyde;
E*2-Butenal; NCI-C56279; Propylene Aldehyde; Topanel; Topanel CA;
trans-2-Butenal; trans-Crotonaldehyde
Chemical Formula: C4H6O
Molecular Weight: 70.10
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(guinea pig) 25.59 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 219.2°F, 104°C (*Sunshine 1969)
Specific Gravity (H2O=1): 0.853 at 20°C/20°C (Merck 1983, p. 372)
Vapor Pressure (mmHg): 19 at 20°C (*Sunshine 1969)
Melting Point: -101°F, -74°C (*Weast 1979)
Vapor Density (AIR=1): 2.41 (Merck 1983, p. 372)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 18.1 g/100 mL at 20°C (Merck 1983, p. 372)
Appearance and Odor: Crotonaldehyde is a water-white to straw-colored
liquid (*NFPA 1978) with a pungent, suffocating odor (ACGIH 1980, p. 107).
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CAS Registry Number: 123-73-9
Page 2 of 4
CROTONALDEHYDE, (E)-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 2 ppm (6 mg/m3) (NIOSH 1987, p. 88)
ACGIH TLV: TWA 2 ppm (6 mg/m3) (ACGIH 1986-87, p. 14)
IDLH: 400 mg/m3 (NIOSH/OSHA 1978, p. 72)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*NFPA 1978)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Although slightly less
toxic, crotonaldehyde is similar chemically and lexicologically to acrolein
(*Gosselin 1976) which is rated as extremely toxic (Gosselin 1984, p.
VI-186). Toxic concentrations for human inhalation have been reported at
12 mg/m3/10 minutes. Irritant dose to human eye is 45 ppm (*NIOSH/RTECS
1985). As with acrolein, vapor exposures cause severe and painful eye
irritation, damage to cornea, lacrimation (tearing), irritation of nasal
membranes, pulmonary edema (filling of lungs with fluid) (*NFPA 1978,
*Rumack 1975 to Present) and gastrointestinal distress when ingested
(*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 13°C (OC) (Merck 1983, p. 372)
Flammable Limits:
LEL: 2.1% (*Sunshine 1969)
UEL: 15.5% (*Sunshine 1969)
Extinguishing Methods: Use dry chemical, foam, or carbon dioxide; water
may be ineffective but should be used to keep fire-exposed containers cool.
If leak or spill has not ignited, use water spray to disperse vapors.
Water spray may be used to flush spills away from exposures (*NFPA 1978).
Special Fire Fighting Procedures: AH exposed skin surfaces should be
covered. Wear protective clothing including self-contained breathing
apparatus, coat, pants, gloves, boots, and bands around arms, wrists, legs,
and waist. Massive or advanced fires should be fought from a safe distance
or protected location (*NFPA 1978). Isolate area for one-half mile in all
directions if tank car or truck involved in fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Vapors form explosive mixtures in air
(*NFPA 1978) or in sewers (*NIOSH/OSHA 1981).
NFPA Flammability Rating: 3
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CAS Registry Number: 123-73-9
Page 3 of 4
CROTONALDEHYDE, (E)-
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Oxygen, heat, elevated pressures (*NFPA 1978)
Incompatibility (Materials to Avoid): Nitric acid (Sax 1984, p. 817).
Hazardous Decomposition or Byproducts: Hazardous peroxides and acids
(*NFPA 1978).
Hazardous Polymerization: May Occur: Yes (*NFPA 1978)
May Not Occur:
Conditions to Avoid: Contact with alkaline materials such as caustic
ammonia or amines, or at elevated temperatures (*NFPA 1978).
SECTION VI -- USE INFORMATION
Chemical intermediate for several compounds in a variety of industrial
processes (surfactants, textiles, paper, fuels, insecticides, leather
tanning, etc.) (*SRI). Used in chemical warfare (Merck 1983, p. 372).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Remove all ignition sources and ventilate area of spill (*NIOSH/OSHA 1981).
No flares, smoking, or flames in hazard area. Do not touch spilled
material; stop leak if you can do so without risk (DOT 1984, Guide 28).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Irritation of eyes causes reddening and
intense lacrimation (tearing) and pain, irritation to nasal membranes and
difficulty in breathing (*Rumack 1975 to Present, *ACGIH 1980); abdominal
distress when ingested (*Rumack 1975 to Present).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration; if
breathing is difficult, give oxygen. Remove and isolate contaminated
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CAS Registry Number: 123-73-9
Page 4 of 4
CROTONALDEHYDE, (E)-
SECTION IX (continued)
clothing and shoes at site if possible. In case of contact with liquid
material, immediately flush skin or eyes with running water for at least 15
minutes (DOT 1984, Guide 28).
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CAS Registry Number: 124-65-2
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM CACODYLATE
CAS Registry Number: 124-65-2
Synonyms: Arsine Oxide, Dimethylhydroxy-, Sodium Salt; Alkarsodyl; Ansar 160;
Ansar 560; Arsecodile; Arsicodile; Arsine Oxide, Hydroxydimethyl-, Sodium Salt;
Arsinic Acid, Dimethyl-, Sodium Salt; Arsycodile; Arsysodila; Cacodylic Acid
Sodium Salt; Cacodylic Acid, Sodium Salt; Chemaid; Hydroxydimethylarsine Oxide,
Sodium Salt; Rad-E-Cate; Silvisar; Sodium Dimethylarsinate; Sodium
Dimethylarsonate; Sodium Salt of Cacodylic Acid; [(Dimethylarsino)oxy]Sodium
As-Oxide
Chemical Formula: C2H7AsO2Na
Molecular Weight: 159.98
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 4 rag/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 140°F, 60°C for trihydrate (*Weast 1979); liquifies in
water of hydration at 140°F, 60°C and becomes anhydrous at 284°F, 120°C for
trihydrate (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 124-65-2
Page 2 of 3
SODIUM CACODYLATE
SECTION II (continued)
Solubility in Water: Soluble; 2000 g/liter at 15-20°C for trihydrate
(*Weast 1979)
Appearance and Odor: White, amorphous crystals or powder (*Hawley 1977)
with a slight odor (*Merck 1976)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.010 mg/m3, as arsenic (NIOSH 1987,
P. 54)
ACGIH TLV: (Arsenic and soluble compounds) TWA 0.2 mg/m3 (ACGIH 1986-87,
p. 10)
IDLH: Not Found
Other Limits Recommended: (Arsenic and compounds) NIOSH: 0.002 mg/m3 15-
minute ceiling, as arsenic (NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Hayes 1982, p. 42)
Health Hazards (Acute, Delayed, and Chronic): Moderately toxic; probable
oral lethal dose in humans is 0.5-5 g/kg or between 1 ounce and 1 pint (or
1 Ib.) for a 70 kg (150 Ib.) person (*Gosselin 1976). It may cause
disturbances of the blood, kidneys, and nervous system (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.)
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area. Stay upwind;
keep out of low areas. Wear self-contained breathing apparatus and full
protective clothing. Move container from fire area, if you can do so
without risk (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: Poisoning potential is high when
heated to decomposition (*Sax 1979).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 124-65-2
Page 3 of 3
SODIUM CACODYLATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Water solution in contact with
active metals (iron, aluminum, zinc) (*Sax 1979)
Hazardous Decomposition or Byproducts: Dangerous when heated to
decomposition or on contact with acids or acid fumes, because it emits
highly toxic fumes of arsenic (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material has been used as a nonselective herbicide and for general
weed control (*Farm Chemicals Handbook 1961).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 124-65-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
SODIUM CACODYLATE
(124-65-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless or white to light yellow crystals or powder.
Odor - None.
Commercial Forms - Colorless to light yellow crystalline solid or concentrated
solution.
Uses - Herbicide, veterinary medicine.
Caution: Avoid sources of extreme heat including fire. Sodium cacodylate will
liberate toxic arsenic fumes when heated to decomposition.
Other Names - Alkarsodyl; Arsecodile; Bophy; cacodylic acid, sodium salt;
Chemaid; Phytar 560; Rad-E-Cate; Silvisar; sodium dimethylarsonate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, sodium
bicarbonate, dimercaprol, penicillamine, dopamine, norepinephrine, KC1.
Signs and Symptoms of Acute Sodium Cacodylate Exposure:
Warning: Effects usually appear within 30 to 60 minutes but may be delayed
for several hours. Caution is advised.
Acute exposure to sodium cacodylate may be fatal. Headache, red-stained eyes,
and a garlicky odor of the breath may be the first effects noticed. Other
signs and symptoms include generalized weakness, intense thirst, muscle
cramping, seizures, toxic delirium, and shock. Nausea, vomiting, anorexia,
abdominal pain, and diarrhea may occur. Hypotension (low blood pressure),
tachycardia (rapid heart rate), pulmonary edema, ventricular fibrillation, and
other cardiac abnormalities are usually found following severe exposure.
Sodium cacodylate is corrosive to the skin, eyes, and mucous membranes.
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EFATG
CAS Registry Number: 124-65-2
Page 2 of 3
SODIUM CACODYLATE
Emergency Life-Support Procedures:
Acute exposure to sodium cacodylate may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to sodium cacodylate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to sodium cacodylate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas for at least 15 minutes with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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EFATG
CAS Registry Number: 124-65-2
Page 3 of 3
SODIUM CACODYLATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 124-87-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PICROTOXIN
CAS Registry Number: 124-87-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 175) Cocculin; Cocculus;
Cocculus Solid; Fish Berry; Indian Berry; Oriental Berry; Picrotin, compound
with Picrotoxinin (1:1); Picrotoxine; 3,6-Methano-8H-l,5,7-
Trioxacyclopenta[ij]Cycloprop[a]Azulene-4,8(3H)-Dione, Hexahydro-2a-Hydroxy-
9-(l-Hydroxy-l-Methylethyl)-8b-Methyl-, [laR-(la.alpha.,2a. beta.,3.beta.,
6.beta.,6a.beta.,8aS*,8b.beta.,9S*)]-, compound with [laR-(la.alpha.,2a.beta.,
3.beta.,6.beta.,6a.beta.,8aS*,8b.beta,9R*)]-Hexahydro-2a-Hydroxy-8b-Methyl-9-
(l-Methylethenyl)-3,6-Methano-8H-l,5,7-Trioxacyclopenta[ij] Cycloprop[a]
Azulene-4,8(3H)-Dione(l:l)
Chemical Formula: C30H34O13 (Weast 1983, p. C456)
Molecular Weight: 602.60 (Weast 1983, p. C456)
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 15 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 397°F, 203°C (Merck 1983, p. 1069)
Vapor Density (AIR=1): Not Found
•T
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 124-87-8
Page 2 of 4
PICROTOXIN
SECTION II (continued)
Solubility in Water: 1 g/350 mL (Merck 1983, p. 1069)
Appearance and Odor: Shiny leaflets with intensely bitter taste (Merck
1983, p. 1069); microcrystalline powder. Odorless (Hawley 1981, p. 816)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Oilman 1985, p. 585)
Skin: Yes (Oilman 1985, p. 585)
Ingestion: Yes (Sax 1984, p. 2231)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic and a dose of
20 mg may produce symptoms of severe poisoning (Oilman 1985, p. 585). A
human lethal dose of 1.5 mg/kg has been reported (NIOSH/RTECS 1983, Volume
3, p. 175). It is an alkaloid convulsant poison (Sax 1984, p. 2231).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Alkaloid) Use dry chemical,
carbon dioxide, water spray, or foam for small fires. Use water spray,
fog, or foam for large fires. Move container from fire area if this can be
done without risk (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Alkaloid) Isolate
hazard area and deny entry. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
acrid smoke and fumes (Sax 1984, p. 2231).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 124-87-8
Page 3 of 4
PICROTOXIN
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Hawley 1981, p. 816)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2231)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Acrid smoke and fumes when heated
to decomposition (Sax 1984, p. 2231)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in medicine as a central nervous system stimulant and antidote for
barbiturate poisoning (Hawley 1981, p. 816). Reportedly, this material is
not currently regarded as a useful therapeutic agent since it is not a
selective respiratory stimulant (Oilman 1985, p. 585).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Alkaloid) Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Remove and isolate contaminated clothing
at the site. If water pollution occurs, notify appropriate authorities.
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 124-87-8
Page 4 of 4
PICROTOXIN
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Picrotoxin is a powerful stimulant and
affects all portions of the central nervous system. At doses approaching
convulsant levels, signs and symptoms include salivation, elevated blood
pressure, frequent vomiting, rapid breathing (Oilman 1985, p. 584).
Emergency and First Aid Procedures: (Non-Specific -- Alkaloid) Move
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. If case
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed, keep victim under observation (DOT 1984, Guide 55).
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CAS Registry Number: 126-98-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHACRYLONITRILE
CAS Registry Number: 126-98-7
Synonyms: 2-Cyano-l-Propene; 2-Cyanopropene; 2-Cyanopropene-l; 2-Methyl-2-
Propenenitrile; 2-Methylacrylonitrile; 2-Methylpropenenitrile; 2-Propene-
nitrile, 2-Methyl-; alpha-Methacrylonitrile; alpha-Methylacrylonitrile;
Isopropene Cyanide; Isopropenylnitrile; USAF ST-40
Chemical Formula: C4H5N
Molecular Weight: 67.10
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.099 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 194°F, 90.3°C (*Merck 1976)
Specific Gravity (H2O=1): 0.8001 at 20/4°C (*Merck 1976)
Vapor Pressure (mmHg): 40 at 12.8°C (*Clayton and Clayton 1981-82)
Melting Point: -32.4°F, -35.8°C (Merck 1983, p. 850)
Vapor Density (AIR=1): 2.31 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 2.57% by weight in water at 20°C; 2.69% by weight in
water at 50°C (*Merck 1976)
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CAS Registry Number: 126-98-7
Page 2 of 3
METHACRYLONITRILE
SECTION II (continued)
Appearance and Odor: Colorless liquid with an odor similar to bitter
almond (*Clayton and Clayton 1981-82; *Encyc Occupat Safety and Health
1971)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 1 ppm (3 mg/ms) (skin) (*ACGIH 1986-87, p. 23)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (*Hawley 1977)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): A lacrimator (causes
tearing); an insidious poison which causes delayed skin reactions (*Merck
1976). Very readily absorbed through skin (*ACGIH 1980). Highly toxic
(*Hawley 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 55°F, 13°C (*Merck 1976)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Usual precautions for flammable liquid should be
applied (*Encyc Occupat Health and Safety 1971).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Methacrylonitrile evolves flammable
concentrations of vapor at temperatures down to 12.8°C. Thus, at room
temperatures, flammable concentrations are liable to be present. Toxic
fumes are released when the material burns. Also, the chemical will
explode due to its tendency to polymerize violently (*Encyc Occupat Health
and Safety 1971).
NFPA Flammability Rating: 3
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Encyc Occupat Health and Safety 1971)
Stable:
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CAS Registry Number: 126-98-7
Page 3 of 3
METHACRYLONITRILE
SECTION V (continued)
Conditions to Avoid: Heat (Sax 1984, p. 1795)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Toxic fumes of nitrogen oxides are
formed upon heating to decomposition (Sax 1984, p. 1795).
Hazardous Polymerization: May Occur: Yes (*Encyc Occupat Health and
Safety 1971)
May Not Occur:
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in the preparation of homopolymers and copolymers; as intermediate in
preparation of acids, amides, amines, nitriles (*Merck 1976). Also used in
the manufacture of elastomers, coatings, plastics (*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Methacrylonitrile cannot be detected by its smell even at concentrations
which are already dangerous for humans. Hence, special attention must be
given to ventilation and estimations of the amount of poison present must
be carried out frequently (*Lefaux 1968).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
PVC POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 126-98-7
Page 1 of 4
Emergency First Aid Treatment Guide
for
METHYLACRYLONITRILE
(126-98-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Methylacrylonitrile toxicity can occur -via ingestion, dermal/eye
contact, or inhalation; death may occur within minutes. IMMEDIATELY begin
administering 100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Similar to bitter almonds (may be imperceptible at toxic levels).
Uses - Chemical intermediate; chemical manufacture of elastomers, coatings,
plastics; preparation of polymers.
Materials to Avoid - Acids, water (except for use in emergency life support).
Caution: Flammable liquid. Avoid sources of extreme heat or ignition
including sparks or fire. May explosively polymerize. Unstable.
Other Names - Alpha-methacrylonitrile; alpha-methylacrylonitrile;
2-cyanopropene; 2-cyano-l-propene; isopropene cyanide; isopropenylnitrile;
2-methylacrylonitrile; 2-methylpropenenitrile; 2-methyl-2-propenenitrile;
2-propenenitrile, 2-methyl; USAF ST-40.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
normal saline, D5W, Ringer's lactate, cyanide antidote kit (amyl nitrite
ampule, sodium nitrite, sodium thiosulfate), sodium bicarbonate, diazepam,
phenytoin.
Signs and Symptoms of Acute Methylacrylonitrile Exposure:
Warning: Effects, including skin reactions, may be delayed. Caution is
advised. Vital signs should be monitored closely. Heart palpitation may begin
within minutes after exposure.
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CAS Registry Number: 126-98-7
Page 2 of 4
METHYLACRYLONITRILE
Note: Methylacrylonitrile is very readily absorbed through the skin.
Signs and symptoms of acute exposure to methylacrylonitrile may include
hypertension (high blood pressure) and tachycardia (rapid heart rate),
followed by hypotension (low blood pressure) and bradycardia (slow heart
rate). Cherry-red mucous membranes and blood, cardiac arrhythmias, and other
cardiac abnormalities are common. Cyanosis (blue tint to the skin and mucous
membranes) is not a consistent finding.
Tachypnea (rapid respiratory rate) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may also occur. Headache, vertigo
(dizziness), agitation, and giddiness may be followed by combative behavior,
convulsions, paralysis, protruding eyeballs, dilated and unreactive pupils, and
coma.
Methylacrylonitrile is irritating to the skin and mucous membranes.
.Lacrimation (tearing) and a burning sensation of the mouth and throat are
common. Excessive salivation, nausea, and vomiting may also occur.
Emergency Life-Support Procedures:
Acute exposure to methylacrylonitrile may require decontamination and life
support for the victims. All exposed persons should be transported to a health
care facility as quickly as possible. Emergency personnel should wear
protective clothing appropriate to the type and degree of contamination. Air-
purifying or supplied-air respiratory equipment should also be worn, as
necessary. Rescue vehicles should carry supplies such as plastic sheeting and
disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methylacrylonitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with methylacrylonitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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CAS Registry Number: 126-98-7
Page 3 of 4
METHYLACRYLONITRILE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methylacrylonitrile.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with methylacrylonitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use
a forced-oxygen mask. Direct oral contact with methylacrylonitrile-
contaminated persons or their gastric contents may result in self-
poisoning.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. DO NOT induce vomiting or attempt to neutralize!
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
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CAS Registry Number: 126-98-7
Page 4 of 4
METHYLACRYLONITRILE
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
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CAS Registry Number: 129-00-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PYRENE
CAS Registry Number: 129-00-0
Synonyms: Benzo[d,e,f]Phenanthrene; Benzo[def]Phenanthrene; beta-Pyrene
Chemical Formula: C16H10
Molecular Weight: 202.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.17 mg/liter (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 5,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 759°F, 404°C (*Merck 1976)
Specific Gravity (H2O=1): 1.27 at 23°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: 313°F, 156°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.135 mg/liter in water (*MacKay 1977)
Appearance and Odor: Colorless solid (Sax 1984, p. 2324); solid and
solutions have a slight blue fluorescence (Merck 1983, p. 1149)
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CAS Registry Number: 129-00-0
Page 2 of 4
PYRENE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: TLV for coal tar pitch volatiles, as benzene
solubles: TWA 0.2 mg/ms. Coal tar pitch volatiles are suspected human
carcinogens (ACGIH 1985, p. 41).
Routes of Entry: Inhalation: Yes (Clayton and Clayton 1981-82,
p. 3361)
Skin: Yes (Hawley 1981, p. 872)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Pyrene is a carcinogenic
agent and is absorbed by the skin (Hawley 1981, p. 872). It is a skin
irritant, a suspected mutagen, and an equivocal tumor-causing agent (Sax
1984, p. 2324). Workers exposed to 3 to 5 mg/m3 of pyrene exhibited some
teratogenic effects (Clayton and Clayton 1981-82, p. 3361). Pyrene is a
polycyclic aromatic hydrocarbon (PAH). The acute toxicity of pure PAHs
appears low when administered orally or dermally to rats or mice (Encyc
Occupat Health and Safety 1983, p. 1758). Human exposure to PAHs
is almost exclusively via the gastrointestinal and respiratory tracts, and
approximately 99 percent is ingested in the diet. Despite the high
concentrations of pyrene to which humans may be exposed through food, there
is currently little information available to implicate diet-derived PAHs as
the cause of serious health effects (NRC 1983, p. ES-6).
Medical Conditions Generally Aggravated by Exposure: Not Found
.SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2324).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 129-00-0
Page 3 of 4
PYRENE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2324)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Biochemical research (Hawley 1981, p. 872).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED**
CPE GOOD/LIMITED**
Neoprene POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 129-00-0
Page 4 of 4
PYRENE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Establish open airway and
respiration. If conscious, induce vomiting with syrup of ipecac. Dermal
exposure should be minimized by washing the exposed surface with soap and
water. Irrigate the eyes with plain tap water (*Rumack 1975 to Present).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
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CAS Registry Number: 129-06-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- WARFARIN SODIUM
CAS Registry Number: 129-06-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 964) Coumarin,
3-(alpha-Acetonylbenzyl)-4-Hydroxy-, Sodium Salt; 3-(alpha-Acetonylbenzyl)-4-
HydroxyCoumarin Sodium Salt; Athrombin; 2H-l-Benzopyran-2-one, 4-Hydroxy-3-
(3-Oxo-l-Phenylbutyl)-, Sodium Salt; Coumadin Sodium; Coumafene Sodium;
Cumadin; Marevan; Marevan (Sodium Salt); Panivarfin; Panwarfin; Prothromadin;
Ratsul Soluble; Sodium, ((3-(alpha-Acetonylbenzyl)-2-Oxo-2H-l-Benzopyran-4-yl)
oxy)-; Sodium Coumadin; Sodium Warfarin; Tintorane; Varfine; Waran; Warcoumin;
Warfarin, Sodium deriv.; Warfarin, Sodium Salt; Warfilone
Chemical Formula: C19H15O4Na
Molecular Weight: 330.33
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 8.7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 129-06-6
Page 2 of 3
WARFARIN SODIUM
SECTION II (continued)
Solubility in Water: Freely soluble (Merck 1983, p. 1441)
Appearance and Odor: Slightly bitter crystalline powder (Merck 1983, p.
1441)
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 812)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally in humans (Sax 1984, p. 812).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Coumarin Derivative Pesticide,
Solid, n.o.s.) Extinguish fires with dry chemical, carbon dioxide, water
spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Wear positive pressure breathing apparatus
and special protective clothing. Remove and isolate contaminated clothing
at the site. Move container from fire area if you can do it without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of sodium oxide (Sax 1984, p. 813).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 129-06-6
Page 3 of 3
WARFARIN SODIUM
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of sodium oxide (Sax 1984, p. 812).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
(Non-Specific -- Coumarins) Anticoagulants used as rodenticides (Encyc
Occupat Health and Safety 1983, p. 560)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Coumarin Derivative Pesticide, Solid, n.o.s.) Do not
touch spilled material; stop leak if you can do it without risk. Use water
spray to reduce vapors. For small spills, take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. For small dry spills, with clean shovel place material into
clean, dry container and cover; move containers from spill area. For large
spills, dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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CAS Registry Number: 129-06-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
WARFARIN SODIUM
(129-06-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Crystalline powder.
Odor - Slightly bitter.
Uses - Rodenticide, anticoagulant.
Other Names - 4-Hydroxy-3-(3-oxo-l-phenylbutyl)-2H-l-benzopyran-2-one, sodium
salt; Warf 42.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
Vitamin K (phytonadione).
Signs and Symptoms of Acute Warfarin Sodium Exposure:
Warfarin sodium is an anticoagulant. Hemorrhage is the most common sign and
may be manifested by hemorrhagic skin rashes and lip, nose, and upper airway
bleeding. Upper airway pain, difficulty in speaking and swallowing, and
dyspnea (shortness of breath) may occur. Vomiting, abdominal pain, and bloody
stools are common. Back pain may be noted.
Emergency Life-Support Procedures:
Acute exposure to warfarin sodium may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
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CAS Registry Number: 129-06-6
Page 2 of 3
WARFARIN SODIUM
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to warfarin sodium.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to warfarin sodium.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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CAS Registry Number: 129-06-6
Page 3 of 3
WARFARIN SODIUM
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of warfarin sodium is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 131-52-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM PENTACHLOROPHENATE
CAS Registry Number: 131-52-2
Synonyms: Dow Dormant Fungicide; Dowicide G; Dowicide G-ST; Mystox D;
Napclor-G; PCP Sodium Salt; PCP-Sodium; Pentachlorophenate Sodium;
Pentachlorophenol Sodium Salt; Pentachlorophenol, Sodium Salt;
Pentachlorophenoxy Sodium; Pentaphenate; Phenol, Pentachloro-, Sodium Salt;
PKHFN; Santobrite; SAPCO 25; Sodium PCP; Sodium Pentachlorophenol; Sodium
Pentachlorophenolate; Sodium Pentachlorophenoxide; Sodium Pentachlorphenate;
Sodium, (Pentachlorophenoxy)-; Weedbeads
Chemical Formula: C6Cl5ONa
Molecular Weight: 288.30
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.24 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 131-52-2
Page 2 of 4
SODIUM PENTACHLOROPHENATE
SECTION II (continued)
Solubility in Water: 330 g/L at 25°C (*Worthing 1979); 21.0 % wt/vol at
5°C; 29.0% wt/vol at 40°C (*Clayton and Clayton 1981-82)
Appearance and Odor: Tan powder (*Sax 1975); powder, pellets, and
briquettes (*Hawley 1977) with a phenolic odor (*Worthing 1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Clayton and Clayton 1981-82)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Clayton and Clayton 1981-82)
Health Hazards (Acute, Delayed, and Chronic): Fine dusts and sprays are
irritating to the eyes and upper respiratory tract. Severe intoxications,
including fatalities, have been reported from uncontrolled use. This
compound causes inflamed gastric mucosa, congestion of the lungs, edema in
the brain, cardiac dilatation, degeneration of the liver and kidneys
(*Encyc Occupat Health and Safety 1971).
Medical Conditions Generally Aggravated by Exposure: Individuals
suffering from kidney and liver diseases have a lowered resistance and
should not be exposed (*Clayton and Clayton 1981-82).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: It is noncombustible (Student 1981, p. 394). For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Wear self-contained (positive pressure)
breathing apparatus and full protective clothing. Move container from fire
area if possible. Runoff from fire control or dilution water may cause
pollution (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 131-52-2
Page 3 of 4
SODIUM PENTACHLOROPHENATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides and sodium oxide (Sax 1984, p. 2446).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Wood preservative (*SRI); preservation of cellulose products, textiles,
paints, adhesives, leather, pulp, paper and industrial waste systems
(*Clayton and Clayton 1981-82); contact and pre-emergence herbicide (*Farm
Chemicals Handbook 1981); general disinfectant (*Worthing 1979) and control
of the intermediate snail host of schistosomiasis (Buchel 1983, p. 220)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill. Collect spilled material in most convenient
manner and deposit in sealed containers for later disposal. Liquids should
be absorbed in vermiculite, dry sand, earth, or similar material
(*NIOSH/OSHA 1981). Keep unnecessary people away; isolate hazard area
and deny entry. Stay upwind; keep out of low areas. Do not touch
spilled material; stop leak if you can do so without risk. Small
spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel, place material into clean, dry container and cover;
move containers from spill area. Large spills: dike far ahead of spill
for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 131-52-2
Page 4 of 4
SODIUM PENTACHLOROPHENATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure to fine dusts or sprays cause
burning in eyes and painful irritation in upper respiratory tract. If
inhaled, it will induce violent coughing and sneezing. Skin irritation
results from brief exposures (*Clayton and Clayton 1981-82). Symptoms of
severe systemic intoxication include loss of appetite, respiratory
difficulties, anesthesia, fever, sweating, difficulty in breathing and
rapidly progressive coma (*Encyc Occupat Health and Safety 1971).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site (DOT 1984, Guide 53). Bathe and shampoo with soap and water.
Flush chemicals from eyes with copious amounts of water. Prevent
absorption. If the material is ingested, the stomach must be emptied
(*Morgan 1976).
-------
CAS Registry Number: 140-29-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BENZYL CYANIDE
CAS Registry Number: 140-29-4
Synonyms: (Cyanomethyl)Benzene; 2-Phenylacetonitrile; Acetic acid,
Phenyl-Nitrile; Acetonitrile, Phenyl-; alpha-Cyanotoluene; alpha-Tolunitrile;
Benzeneacetonitrile; Benzyl Nitrile; omega-Cyanotoluene; Phenylacetonitrile;
Toluene, alpha-Cyano; USAF KF-21
Chemical Formula: C8H7N
Molecular Weight: 117.14
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.43 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 451.4°F, 233.5°C (*Merck 1976)
Specific Gravity (H2O=1): 1.0214 at 15°C (*Merck 1976)
Vapor Pressure (mmHg): 1 at 60°C (*Sax 1979)
Melting Point: -10.8°F, -23.8°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor:--Benzyl cyanide is a colorless, oily liquid with an
aromatic odor (*Hawley 1977; *Merck 1976)
-------
CAS Registry Number: 140-29-4
Page 2 of 3
BENZYL CYANIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2171)
Skin: Yes (Hawley 1981, p. 122)
Ingestion: Yes (Sax 1984, p. 2171)
Health Hazards (Acute, Delayed, and Chronic): Poisonous. May be fatal if
inhaled, swallowed, or absorbed through skin. Contact may cause burns to
skin and eyes (DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam. Move container
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of cyanide and nitrogen oxides (Sax 1984, p. 2171).
Container may explode in heat of fire. Runoff from fire control water may
give off poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: 1
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 140-29-4
Page 3 of 3
BENZYL CYANIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Sodium hypochlorite (Sax 1984, p.
2171)
»
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of cyanide and nitrogen oxides (Sax 1984, p. 2171).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Organic synthesis, especially penicillin precursors (*Hawley 1977).
Chemical intermediate for amphetamines, phenobarbital, the stimulant,
methyl phenidylacetate, esters as perfumes and flavors (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing vapors (see Section III above). Do not touch spilled
materials; stop leak if you can do it without risk. Use water spray to
reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal.
Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 140-29-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
BENZYL CYANIDE
(140-29-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless, oily liquid.
Odor - Aromatic.
Commercial Form - Liquid in metal drums, tins, or bottles.
Uses - Manufacture of Pharmaceuticals, penicillin, perfumes, and flavors.
Material to Avoid - Water (except for use in emergency life support).
Caution: Avoid sources of heat including fire. Benzyl cyanide will liberate
toxic fumes of cyanide and nitrogen oxides when heated to decomposition.
Other Names - Benzeneacetonitrile, benzyl nitrile, (cyanomethyl) benzene,
phenylacetonitrile, alpha-tolunitrile, USAF KF-21.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, cyanide antidote
kit (amyl nitrite ampule, sodium nitrite, sodium thiosulfate), sodium
bicarbonate, diazepam, phenytoin.
Signs and Symptoms of Acute Benzyl Cyanide Exposure:
Warning: Benzyl cyanide may be fatal if inhaled, swallowed, or absorbed
through skin or mucous membranes. Caution is advised.
Signs and symptoms of acute exposure to benzyl cyanide may include
hypertension (high blood pressure) and tachycardia (rapid heart rate), followed
by hypotension (low blood pressure) and bradycardia (slow heart rate). Cherry-
red or bloody mucous membranes may be noted. Cardiac arrhythmias and other
cardiac abnormalities are common. Cyanosis (blue tint to the skin and mucous
membranes) may be observed.
-------
EFATG
CAS Registry Number: 140-29-4
Page 2 of 3
BENZYL CYANIDE
Headache, vertigo (dizziness), agitation, and giddiness may be followed by
combative behavior, convulsions, paralysis, protruding eyeballs, dilated and
unreactive pupils, and coma. Tachypnea (rapid, shallow respirations) or
hyperpnea (rapid, deep respirations) may be followed by respiratory depression.
Lung hemorrhage and pulmonary edema may also occur.
Benzyl cyanide is irritating to the skin, eyes, and mucous membranes.
Lacrimation (tearing) and a burning sensation of the mouth and throat are
common. Salivation, nausea, and vomiting may also occur.
Emergency Life-Support Procedures:
Acute exposure to benzyl cyanide may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
.clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to benzyl cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with benzyl cyanide-contaminated
persons or their gastric contents can result in self-poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to benzyl cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
-------
EFATG
CAS Registry Number: 140-29-4
Page 3 of 3
BENZYL CYANIDE
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with benzyl cyanide-contaminated
persons or their gastric contents can result in self-poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with benzyl cyanide-contaminated
persons or their gastric contents can result in self-poisoning.
2. RUSH to a health care facility!
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 140-76-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ PYRIDINE, 2-METHYL-5-VINYL-
CAS Registry Number: 140-76-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 423): 2-Methyl-
5-Ethenylpyridine; Pyridine, 5-Ethenyl-2-Methyl-; 2-Methyl-5-Vinylpyridine;
2-Picoline, 5-Vinyl-
Chemical Formula: C8H9N
Molecular Weight: 119.18
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.189 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 358°F, 181°C (Hawley 1981, p. 692)
Specific Gravity (H2O=1): 0.978-0.982 20°C/20°C (Hawley 1981, p. 692)
Vapor Pressure (mmHg): Not Found
Melting Point: Freezing point: 6.3°F, -14.3°C (anhydrous) (Hawley 1981,
p. 692)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: "^Clear to faintly opalescent liquid (Hawley 1981, p.
692)
-------
CAS Registry Number: 140-76-1
Page 2 of 4
PYRIDINE, 2-METHYL-5-VINYL-
SECTION HI ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1944)
Skin: Yes (Sax 1984, p. 1944)
Ingestion: Yes (Sax 1984, p. 1944)
Health Hazards (Acute, Delayed, and Chronic): This material is moderately
toxic by ingestion, inhalation, and absorption through the skin (Sax 1984,
p. 1944).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 165°F, 73.9°C (TOC) (Hawley 1981, p. 692)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: It is combustible (Hawley 1981, p. 692).
(Non-Specific -- Combustible Liquid, n.o.s.) Extinguish with dry chemical,
carbon dioxide, water spray, fog, or foam (DOT 1984, Guide 27).
Special Fire Fighting Procedures: (Non-Specific -- Combustible Liquid,
n.o.s.) Wear self-contained (positive pressure if available) breathing
apparatus and full protective clothing. Isolate for 1/2 mile in all
directions if tank car or truck is involved in fire. Move container from
fire area if you can do so without risk. Spray cooling water on containers
that are exposed to flames until well after fire is out. For massive fire
in cargo area, use unmanned hose holder or monitor nozzles; if this is
impossible, withdraw from area and let fire burn. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire (DOT 1984, Guide 27).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1944). (Non-Specific --
Combustible Liquid, n.o.s.) Flammable/combustible material; may be ignited
by heat, sparks, or flames. Vapors may travel to a source of ignition and
flash back. Container may explode in heat of fire (DOT 1984, Guide 27).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 140-76-1
Page 3 of 4
PYRIDINE, 2-METHYL-5-VINYL-
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxide (Sax 1984, p. 1944).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a monomer for resins; oil additive, ore flotation agent; and dye
acceptor (Hawley 1981, p. 692).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Combustible Liquid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Shut off ignition sources; no flares, smoking, or flames in hazard area.
Stop leak if you can do so without risk. Use water spray to reduce vapors.
Absorb spills with sand or noncombustible absorbent material. For large
spills dike far ahead (DOT 1984, Guide 27).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific - Combustible Liquid,
n.o.s.) Vapors may cause dizziness or suffocation (DOT 1984, Guide 27).
Emergency and First Aid Procedures: (Non-Specific — Combustible Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
-------
CAS Registry Number: 140-76-1
Page 4 of 4
PYRIDINE, 2-METHYL-5-VINYL-
SECTION IX (continued)
oxygen. In case of contact with material, immediately flush eyes with
running water for at least 15 minutes. Wash skin with soap and water.
Remove and isolate contaminated clothing and shoes at the site (DOT 1984,
Guide 27).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Weast 1979
Merck 1983
Student 1981
CHRIS 1978
Doull 1980
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Gilman 1985
Clayton and Clayton 1981-82
NFPA 1984
Weiss 1980
-------
CAS Registry Number: 141-66-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DICROTOPHOS
CAS Registry Number: 141-66-2
Synonyms: 3-(Dimethoxyphosphinyloxy)-N,N-Dimethyl-cis-Crotonamide;
3-(Dimethylamino)-l-Methyl-3-Oxo-l-Propenyl Dimethyl Phosphate (E)-Isomer;
3-Dimethoxyphosphinyloxy-N,N-Dimethylisocrotonamide; 3-Hydroxy-N,N-
Dimethyl-cis-Crotonamide Dimethyl Phosphate; 3-Hydroxydimethyl Crotonamide
Dimethyl Phosphate; Bidrin; C 709; Carbicron; Carbomicron; Ciba 709,
Cis-2-Dimethylcarbamoyl-l-Methylvinyl Dimethylphosphate; Crotonamide,
3-Hydroxy-N,N-Dimethyl-, cis-, Dimethyl Phosphate; Dimethyl (E)-2-Dimethyl-
Carbamoyl-1-Methylvinyl Phosphate; Dimethyl l-Dimethylcarbamoyl-l-Propen-2-yl
Phosphate; Dimethyl 2-Dimethylcarbamoyl-l-Methylvinyl Phosphate; Phosphoric
Acid, Dimethyl Ester, Ester with cis-3-Hydroxy-N,N-Dimethylcrotonamide;
Dimethyl Phosphate Ester with 3-Hydroxy-N,N-Dimethylcrotonamide; Dimethyl
Phosphate of 3-Hydroxy-N,N-Dimethyl-cis-Crotonamide; Ektafos; ENT 24,482;
Karbicron; O,O-Dimethyl O-(N,N-Dimethylcarbamoyl-l-Methylvinyl) Phosphate;
O,O-Dimethyl O-(l,4-Dimethyl-3-Oxo-4-Azapent-l-enyl) Phosphate; Oleobidrin;
Phosphoric acid, Dimethyl Ester, Ester with (E)-3-Hydroxy-N,N-Dimethyl-
crotonamide; SD 3562; Shell SD-3562; Phosphoric Acid, 3-(Dimethylamino)-l-
Methyl-3-oxo-l- Propenyl Dimethyl Ester, (E)-; Crotonamide, 3-Hydroxy-N,N-
Dimethyl-, Dimethyl Phosphate, cis-; Crotonamide, 3-Hydroxy-N,N-Dimethyl-,
Dimethyl Phosphate, (E)-
Chemical Formula: C8H16NO5P
Molecular Weight: 237.21
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.09 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
•>r
Boiling Point: 752°F, 400°C (*Merck 1976)
-------
CAS Registry Number: 141-66-2
Page 2 of 4
DICROTOPHOS
SECTION II (continued)
Specific Gravity (H2O=1): 1.216 at 15°C/15°C (*Merck 1976)
Vapor Pressure (mmHg): 0.00001 at 20°C (Worthing 1983, p. 190)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Sax 1979)
Appearance and Odor: Dicrotophos is a yellow to brown liquid with a mild
ester odor (*Spencer 1973; *Worthing 1979).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.25 mg/m3 (skin) (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hayes 1982, pp. 361-362)
Skin: Yes (Hayes 1982, pp. 361-362)
Ingestion: Yes (Hayes 1982, pp. 361-362)
Health Hazards (Acute, Delayed, and Chronic): It is extremely toxic.
Probable human oral lethal dose is 5 to 50 mg/kg, 7 drops to one
teaspoonful for a 70 kg (150 Ib.) person. Closely related in toxicity to
azodrin (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Above 175°F (*Farm Chemicals Handbook 1981)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray,
fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
-------
CAS Registry Number: 141-66-2
Page 3 of 4
DICROTOPHOS
SECTION IV (continued)
for later disposal; do not scatter the material. Wear positive pressure
breathing apparatus and special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) This material may burn but does not ignite
readily. Container may explode in heat of fire. Fire and runoff from fire
control water may produce irritating or poisonous gases (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Keep away from heat and open flame (*Farm
Chemicals Handbook 1981).
Incompatibility (Materials to Avoid): Rapidly hydrolyzes in acid or
alkali (*Sunshine 1969).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used to control sucking, boring, and chewing pests on rice, cotton, coffee,
apples, and other crops. Effective on ornamentals, trees, and shrubs for
aphids, leaf hoppers, and scale insects (*Worthing 1979; *Spencer 1973;
*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, Liquid, n.o.s.) Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal. Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Remove and isolate contaminated clothing
at the site (DOT 1984, Guide 55). ;
-------
CAS Registry Number: 141-66-2
Page 4 of 4
DICROTOPHOS
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 141-66-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
DICROTOPHOS
(141-66-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Yellow liquid.
Odor - Esterlike.
Commercial Form - Brown, aqueous solution.
Use - Pesticide.
Materials to Avoid - Acids, alkali.
Other Names - Bidrin, Carbicron, Carbomicron, Ektafos, Karbicron,
3-(dimethyoxyphosphinyloxy)-N,N-dimethyl-cis-crotonamide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Dicrotophos Exposure:
Note: Dicrotophos is a cholinesterase inhibitor.
Acute exposure to dicrotophos may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) is not uncommon.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
-------
EFATG
CAS Registry Number: 141-66-2
Page 2 of 3
DICROTOPHOS
Emergency Life-Support Procedures:
Acute exposure to dicrotophos may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to dicrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to dicrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 141-66-2
Page 3 of 3
DICROTOPHOS
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of dicrotophos is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of dicrotophos may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 143-33-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM CYANIDE (Na(CN))
CAS Registry Number: 143-33-9
Synonyms: Cyanide of Sodium; Cyanogran; Cymag; Hydrocyanic Acid, Sodium salt;
Sodium Cyanide, Solid (DOT)
Chemical Formula: NaCN
Molecular Weight: 49.01
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(domestic animal) 4 mg/kg (*N1OSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): In Cyanide Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 2725°F, 1496°C (*Weast 1979)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 1 at 817°C (*Clayton and Clayton 1981-82)
Melting Point: 1047°F, 564°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 82 g/100 cc at 35°C (*Weast 1979)
Appearance and Odor: White solid in form of granules, flakes, or eggs
(resembling chicken eggs) (*NFPA 1978); colorless cubes (*Weast 1979);
odorless when perfectly dry but emits odor of hydrogen cyanide when damp
(*Merck 1983) *
-------
CAS Registry Number: 143-33-9
Page 2 of 3
SODIUM CYANIDE (Na(CN))
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 mg (Cyanide)/ms (Skin) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 5 mg (Cyanide)/ms (*ACGIH 1983)
IDLH: 50 mg/m3 (NIOSH/OSHA 1978, p. 74)
Other Limits Recommended: The recommended upper limit for occupational
exposure to cyanide salts is 5 mg (Cyanide)/ms/10 min (*NIOSH/RTECS 1985).
Routes of Entry: Inhalation: Yes (*Clayton and Clayton 1981-82)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Clayton and Clayton 1981-82)
Health Hazards (Acute, Delayed, and Chronic): Super toxic; probable oral
lethal dose in humans is less than 5 mg/kg or a taste (less than 7 drops)
..for a .70 kg (150 Ib.) person (*Gosselin 1976). Sodium cyanide is poisonous
and may be fatal if inhaled, swallowed or absorbed through the skin.
Contact with sodium cyanide may cause burns to skin and eyes (*DOT 1984).
Medical Conditions Generally Aggravated by Exposure: Individuals with
chronic diseases of the kidneys, respiratory tract, skin, or thyroid are at
greater risk of developing toxic cyanide effects (*Encyc Occupat Health and
Safety 1983).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not combustible (NFPA 1984, p. 49-81)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water (*NFPA 1978). Use dry chemical, carbon
dioxide, water spray, or foam for small fires, water spray, fog, or foam
for large fires (*DOT 1984).
Special Fire Fighting Procedures: Full protective clothing including
self-contained breathing apparatus, rubber gloves, boots, and bands around
legs, arms, and waist should be provided. No skin surface should be
exposed. Normal fire fighting procedures may be used (*NFPA 1978). Fight
fire from maximum distance. Move container from area if you can do it
without risk. Dike fire control water for later disposal. Do not scatter
the material (*DOT 1984).
Unusual Fire and Explosion Hazards: Sodium cyanide is not combustible
itself, but contact with acids releases highly flammable hydrogen cyanide
gas (*NFPA 1978). Fire may produce irritating or poisonous gases. Runoff
from fire control water may give off poisonous gases. Container may
explode in the heat of fire (*DOT 1984).
NFPA Flammability Rating: 0
-------
CAS Registry Number: 143-33-9
Page 3 of 3
SODIUM CYANIDE (Na(CN))
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Avoid contact with acids (*NFPA 1978). Aqueous
solutions rapidly decompose (*Hawley 1977).
Incompatibility (Materials to Avoid): Strong oxidizers such as nitrates
and chlorates; acids and acid salts (NIOSH/OSHA 1978, p. 74)
Hazardous Decomposition or Byproducts: Hydrogen cyanide (*NFPA 1978)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Sodium cyanide is used as a fumigant (*Merck 1983), a rodenticide (*Morgan
1982), in cleaning metals, and in the manufacturing of dyes and pigments,
as a chelating compound (*Hawley 1977), as a component of electroplating
solutions, as a component of salts for case hardening steel, and as an
agent for extraction of gold and silver from ores (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Evacuate the area immediately (*Encyc Occupat Health and Safety 1983).
Do not touch spilled material; stop leak if you can do it without risk.
Use water spray to reduce vapors. Small spills: take up with sand or
other noncombustible absorbent material and place into containers
for later disposal. Small dry spills: with clean shovel place material
into clean, dry container and cover; move containers from spill area.
Large spills: dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 143-33-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
SODIUM CYANIDE
(143-33-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Sodium cyanide toxicity can occur via ingestion, dermal/eye contact,
or inhalation; death may occur within minutes. IMMEDIATELY begin administering
100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Forms - White deliquescent, crystalline powder.
Odor - None when dry; bitter, almondlike when damp.
Commercial Forms - White granules, flakes, or eggs in carboys.
Uses - Metal cleaning, electroplating, steel hardening, chelation, gold and
silver extraction; fumigant, rodenticide, dyes.
Materials to Avoid - Acids.
Other Names - Cyanogran; Cymag; hydrocyanic acid, sodium salt.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, cyanide antidote kit (amyl nitrite ampule, sodium nitrite,
sodium thiosulfate), activated charcoal, saline cathartic or sorbitol, sodium
bicarbonate, diazepam, phenytoin.
Signs and Symptoms of Acute Sodium Cyanide Exposure:
Warning: Heart palpitations may occur within minutes after exposure. Caution
is advised. Effects may be delayed.
Signs and symptoms of acute exposure to sodium cyanide may include hypertension
(high blood pressure) and tachycardia (rapid heart rate), followed by
hypotension (low blood pressure) and bradycardia (slow heart rate). Cardiac
arrhythmias and other cardiac abnormalities are common. Cyanosis (blue tint to
the skin and mucous membranes) and cherry-red or bloody mucous membranes may
occur.
-------
EFATG
CAS Registry Number: 143-33-9
Page 2 of 3
SODIUM CYANIDE
Tachypnea (rapid respiratory rate) may be followed by respiratory depression.
Pulmonary edema and lung hemorrhage may also occur. Headache, vertigo
(dizziness), agitation, and giddiness may be followed by combative behavior,
dilated and unreactive pupils, convulsions, paralysis, and coma.
Sodium cyanide is irritating to the skin and mucous membranes. Lacrimation
(tearing) and a burning sensation of the mouth and throat are common.
Increased salivation, nausea, and vomiting are often seen.
Emergency Life-Support Procedures:
Acute exposure to sodium cyanide may require decontamination and life support
for the victims. All exposed persons should be transported to a health care
facility as quickly as possible. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to sodium cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with sodium cyanide-contaminated
persons or their gastric contents may result in self-poisoning.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to sodium cyanide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
-------
EFATG
CAS Registry Number: 143-33-9
Page 3 of 3
SODIUM CYANIDE
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with sodium cyanide-contaminated
persons or their gastric contents may result in self-poisoning.
3. RUSH to a health care facility!
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. Wash exposed skin areas twice with soap and water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. IMMEDIATELY begin administering 100% oxygen to
all victims. Monitor victims for respiratory distress.
Warning: To prevent self-poisoning, avoid mouth-to-mouth breathing; use a
forced-oxygen mask. Direct oral contact with sodium cyanide-contaminated
persons or their gastric contents may result in self-poisoning.
2. RUSH to a health care facility!
3. DO NOT induce vomiting. Ipecac is not recommended for ingestion of sodium
cyanide.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 824-11-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ TRIMETHYLOLPROPANE PHOSPHITE
CAS Registry Number: 824-11-3
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 298) 1,3-Propanediol,
2-Ethyl-2-(Hydroxymethyl)-, Cyclic Phosphite (1:1); 4-Ethyl-
l-Phospha-2,6,7-Trioxabicyclo[2.2.2]Octane; 4-Ethyl-2,6,7-Trioxa-l-
Phosphabicyclo[2.2.2]Octane; 2-(Hydroxymethyl)-2-Ethyl-l,3-Propanediol, Cyclic
Phosphite (1:1); 1,1,1-Tris-hydroxymethylpropane Bicyclic Phosphite
Chemical Formula: C6HnO3P
Molecular Weight: 162.14
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (cat)
2.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 824-11-3
Page 2 of 3
TRIMETHYLOLPROPANE PHOSPHITE
SECTION HI -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Ratiug: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
-------
CAS Registry Number: 824-11-3
Page 3 of 3
TRIMETHYLOLPROPANE PHOSPHITE
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENT
Sources searched but no information found:
Clayton and Clayton 1981-82
Weast 1979
Verschueren 1983
Merck 1983
Sax 1984
Student 1981
NFPA 1984
Gosselin 1984
Hayes 1982
-------
CAS Registry Number: 900-95-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: June 22, 1987
Revision: November 30, 1987
CHEMICAL IDENTITY -- STANNANE, ACETOXYTRIPHENYL-
CAS Registry Number: 900-95-8
Synonyms: Acetatotriphenylstannane; Acetoxy-triphenylstannane;
(Acetyloxy)triphenylstannane; Acetoxytriphenylstannane; Acetoxytriphenyltin;
Acetyloxytriphenylstannane; Batasan; Brestan; Brestan 60; ENT 25208; Fenolovo
Acetate; Fentin Acetate; GC 6936; HOE-2824; Liromatin; Lirostanol;
Phentinoacetate; Phehtin Acetate; Stannane, (Acetyloxy)Triphenyl-; Suzu; Tin,
Acetoxytriphenyl-; Tinestan; Tinestan 60 WP; Tin Triphenyl Acetate; TPTA;
TPZA; Triphenylaceto Stannane; Triphenyltin Acetate; Tubotin; VP 1940; VP 19-40
Chemical Formula: C2oH1gO2Sn
Molecular Weight: 409.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 21 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.55 at 20°C (*Hartley and Kidd 1983)
Vapor Pressure (mmHg): 0.000000014 (1.9 uPa) at 60°C (*Worthing 1983)
Melting Point: 252°F, 122°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 9 mg/liter at 20°C (*Worthing 1983)
-------
CAS Registry Number: 900-95-8
Page 2 of 4
STANNANE, ACETOXYTRIPHENYL-
SECTION II (continued)
Appearance and Odor: Colorless (*Worthing 1983) to white crystalline
solid (*Hawley 1981) to small needles (*Merck 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Tin, organic compounds) 0.1 mg/ms, as tin (NIOSH 1987, p.224)
ACGIH TLV: (Tin, organic compounds) 0.1 mg/ms, as tin (skin) (ACGIH
1986-87)
IDLH: Not Found
Other Limits Recommended: IDLH for tin organic compounds 200 mg/m3, as
tin (NIOSH 1987, p. 224). NIOSH: (Tin organic compounds) 10.1 mg/ms
(as tin) 10 hour TWA (NIOSH 1987, p. 224).
Routes of Entry: Inhalation: Yes (*Gosselin 1984)
Skin: Yes (*Rumack 1975-Present)
Ingestion: Yes (*Weast 1983-84)
Health Hazards (Acute, Delayed, and Chronic): Very toxic (*Weast 1983-84);
irritant to skin (*Hawley 1981).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organotin pesticide, n.o.s.)
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organotin pesticide,
n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces
before entering them. Wear positive pressure breathing apparatus and
special protective clothing. Move container from fire area if you can do
so without risk. Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 900-95-8
Page 3 of 4
STANNANE, ACETOXYTRIPHENYL-
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1983)
Conditions to Avoid: Air, light (*Worthing 1983), and moisture
(*Spencer 1973)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as an antifeeding compound for insect pest control, a fungicide
(*Merck 1983), an algicide, and a molluscicide (*Farm Chemicals Handbook
1981).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organotin pesticide, n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material;
stop leak if you can do it without risk. Use water spray to reduce
vapors. Small spills: absorb with sand or other noncombustible absorbent
material and place into containers for later disposal. Small dry spills:
with clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include severe headache,
nausea, vomiting and abdominal pain. There may be sugar in the urine
-------
CAS Registry Number: 900-95-8
Page 4 of 4
STANNANE, ACETOXYTRIPHENYL-
SECTION IX (continued)
and high blood sugar. Dizziness and loss of consciousness may occur
(*Gosselin 1984).
Emergency and First Aid Procedures: (Non-Specific -- Organotin
pesticide, n.o.s.) Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 919-86-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DEMETON-S-METHYL
CAS Registry Number: 919-86-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 158) Phosphorothioic
Acid, S-(2-(Ethylthio)Ethyl) O,O-Dimethyl Ester; BAY 18436; Bayer 25/154;
O,O-Dimethyl S-(2-Eththioethyl) Phosphorothioate; Dimethyl S-(2-Eththioethyl)
Thiophosphate; O,O-Dimethyl S-(Ethylmercapto)ethyl Thiophosphate; O,O-Dimethyl
2-Ethylmercaptoethyl Thiophosphate, Thiolo Isomer; O,O-Dimethyl
S-(2-(Ethylthio)Ethyl) Phosphorothioate; Isometasystox; Isomethylsystox;
Ethanethiol, 2-(Ethylthio)-, S-Ester with O,O-Dimethyl
Phosphorothioate; S-(2-(Ethylthio)Ethyl) O,O-Dimethyl Phosphorothioate;
S-(2-(Ethylthio)Ethyl) Dimethyl Phosphorothiolate; S-(2-(Ethylthio)Ethyl)
O,O-Dimethyl Thiophosphate; Metaisoseptox; Metaisosystox; Metasystox Forte;
Metasystox (I); Metasystox J; Methyl Demeton Thioester; Methyl Isosystox;
Methyl-Mercaptofos Teolovy; Phosphorothioic Acid, O,O-Dimethyl
S-(2-(Ethylthio)Ethyl) Ester
Chemical Formula: C6H15OSPS2
Molecular Weight: 230.30
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.5 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 192°F, 89°C at 0.15 mmHg (Merck 1983, p. 867)
Specific Gravity (H2O=1): 1.207 at 20°C/4°C (Merck 1983, p. 867)
Vapor Pressure (mmHg): 0.00036 at 20°C (Worthing 1979, p. 155)
-------
CAS Registry Number: 919-86-8
Page 2 of 4
DEMETON-S-METHYL
SECTION II (continued)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (3300 ppm) (Merck 1983, p. 867)
Appearance and Odor: Pale yellow oil (Merck 1983, p. 867)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 865)
Skin: Yes (Sax 1984, p. 865)
Ingestion: Yes (Sax 1984, p. 865)
Health Hazards (Acute, Delayed, and Chronic): It inhibits the nervous
system and is absorbed readily through the skin (Merck 1983, p. 867). This
compound is a liquid organophosphorus insecticide (Buchel 1983, p. 66).
Poisonous; may be fatal if inhaled, swallowed or absorbed through skin.
Contact may cause burns to skin and eyes (DOT 1984, Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a liquid organophosphorus
insecticide (Buchel 1983, p. 66). Small fires: dry chemical, carbon
dioxide, water spray, or foam. Large fires: water spray, fog or foam.
Move container from fire area if you can do so without risk. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is a liquid
organophosphorus insecticide (Buchel 1983, p. 66). Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Wear positive
-------
CAS Registry Number: 919-86-8
Page 3 of 4
DEMETON-S-METHYL
SECTION IV (continued)
pressure breathing apparatus and special protective clothing. Remove and
isolate contaminated clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of oxides of phosphorus and sulfur (Sax 1984, p.
865). This compound is a liquid organophosphorus insecticide (Buchel 1983,
p. 66). This material may burn but does not ignite readily. Container may
explode in heat of fire. Fire may produce irritating or poisonous gases.
Runoff from fire control water may give off poisonous gases (DOT 1984,
Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Hydrolyzed by alkali (Hayes 1982, p. 341)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of phosphorus and sulfur (Sax 1984, p.
865).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is an insecticide (Merck 1983, p. 867). Not registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is a liquid organophosphorus insecticide (Buchel 1983, p.
66). Do not touch spilled material; stop leak if you can do so without
risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
-------
CAS Registry Number: 919-86-8
Page 4 of 4
DEMETON-S-METHYL
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 919-86-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
DEMETON-S-METHYL
(919-86-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Pale yellow oil.
Use - Insecticide.
Other Names - Methylsystox, methyl-mercaptophos, O,O-dimethyl
S-(ethylmercapto)ethyl thiophosphate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Demeton-S-Methyl Exposure:
Warning: Demeton-s-methyl is readily absorbed through the skin.
Note: Demeton-s-methyl is a cholinesterase inhibitor.
Acute exposure to demeton-S-methyl may produce the following signs and
symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms,
and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma
may also occur. The heart rate may decrease following oral exposure or
increase following dermal exposure. Hypotension (low blood pressure) is not
uncommon. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
-------
EFATG
CAS Registry Number: 919-86-8
Page 2 of 3
DEMETON-S-METHYL
Emergency Life-Support Procedures:
Acute exposure to demeton-S-methyl may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to demeton-S-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to demeton-S-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 919-86-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
DEMETON-S-METHYL
(919-86-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Pale yellow oil.
Use - Insecticide.
Other Names - Methylsystox, methyl-mercaptophos, O,O-dimethyl
S-(ethylmercapto)ethyl thiophosphate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Demeton-S-Methyl Exposure:
Warning: Demeton-s-methyl is readily absorbed through the skin.
Note: Demeton-s-methyl is a cholinesterase inhibitor.
Acute exposure to demeton-S-methyl may produce the following signs and
symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms,
and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma
may also occur. The heart rate may decrease following oral exposure or
increase following dermal exposure. Hypotension (low blood pressure) is not
uncommon. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
-------
EFATG
CAS Registry Number: 919-86-8
Page 2 of 3
DEMETON-S-METHYL
Emergency Life-Support Procedures:
Acute exposure to demeton-S-methyl may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to demeton-S-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to demeton-S-methyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 919-86-8
Page 3 of 3
DEMETON-S-METHYL
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of demeton-s-methyl is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of demeton-s-methyl may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
.fse 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 920-46-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHACRYLOYL CHLORIDE
CAS Registry Number: 920-46-7
Synonyms: (SANSS 1983 Synonyms): 2-Propenoyl Chloride, 2-Methyl-; Methacryl
Chloride; Methacrylic Acid Chloride; Methacrylic Chloride; Methacrylyl
Chloride; Methylacryloyl Chloride
Chemical Formula: C4H6C1O
Molecular Weight: 105
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.06 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 205°F, 96°C (Weast 1983, p. C-371)
Specific Gravity (H2O=1): 1.0871 at 20°C/4°C (Weast 1983, p. C-371)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 920-46-7
Page 2 of 3
METHACRYLOYL CHLORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 920-46-7
Page 3 of 3
METHACRYLOYL CHLORIDE
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
Sax 1984
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
Verschueren 1983
-------
CAS Registry Number: 944-22-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FONOFOS
CAS Registry Number: 944-22-9
Synonyms: Phosphonodithioic Acid, Ethyl-, O-Ethyl S-Phenyl Ester; Dyphonate;
Difonate; Difonatul; Dyfonat; Dyfonate; Ethylphosphonodithioic Acid O-Ethyl
S-Phenyl Ester; Fonofos; O-Ethyl S-Phenyl Ethyldithiophosphonate; O-Ethyl
S-Phenyl Ethylphosphonothiolothionate; Phosphonodithioic Acid, Ethyl-, O-Ethyl
S-Phenyl Ester; ENT 25,796; N 2790; N-2790; Stauffer N 2790
Chemical Formula: C10H15OPS2
Molecular Weight: 246.32
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(domestic animal) 1.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 266°F, 130°C at 0.1 mmHg (*Merck 1976)
Specific Gravity (H2O=I): 1.16 at 25°C (*Merck 1976)
Vapor Pressure (mmHg): 0.00021 at 25°C ('Worthing 1979)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 13 ppm at 22°C (*Spencer 1973)
-------
CAS Registry Number: 944-22-9
Page 2 of 4
FONOFOS
SECTION II (continued)
Appearance and Odor: Light yellow liquid (*Merck 1976); pungent
mercaptan-like odor (*Worthing 1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/m8 (skin) (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organic Phosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): This material is a
cholinesterase inhibitor (*Merck 1976). It can cause severe symptoms and
death from respiratory arrest (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV « FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a liquid organophosphorus
insecticide (Buchel 1983, p. 82). Extinguish with dry chemical, carbon
dioxide, water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is a liquid
organophosphorus insecticide (Buchel 1983, p. 82). Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Wear positive
pressure breathing apparatus and special protective clothing. Remove and
isolate contaminated clothing at the site. Move container from fire area
if you can do so without risk. Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: When this material is heated to
decomposition, it can emit highly toxic fumes of phosphorus oxides (*Sax
1979).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 944-22-9
Page 3 of 4
FONOFOS
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated it can emit highly
toxic fumes of phosphorus oxides (*Sax 1979),
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used primarily as an insecticide for corn (*Spencer 1973).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is a liquid organophosphorus insecticide (Buchel 1983, p.
82). Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Remove and isolate contaminated clothing at the site.
Do not touch spilled material; stop leak if you can do so without risk.
Use water spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 944-22-9
Page 4 of 4
FONOFOS
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
vertigo, sensation of tightness in chest, blurring of vision, ocular pain,
loss of muscle coordination, slurring in speech, muscle twitching,
drowsiness, excessive secretion of respiratory tract mucous, and
convulsions (*Gosselin 1976).
Emergency and First Aid Procedures: This compound is a liquid
organophosphorus insecticide (Buchel 1983, p. 82). Move victim to fresh
air; call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least IS minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
be delayed; keep victim under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 947-02-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHOSFOLAN
CAS Registry Number: 947-02-4
Synonyms: Imidocarbonic Acid, Phosphonodithio-, Cyclic Ethylene P,P-Diethyl
Ester; Cyolane; (Diethoxyphosphinyl)Dithioimidocarbonic Acid Cyclic Ethylene
Ester; 1,2-Ethanedithiol, Cyclic Ester with P,P-Diethyl
Phosphonodithioimidocarbonate; 1,2-Ethanedithiol, Cyclic S,S-Ester with
Phosphonodithioimidocarbonic Acid P,P-Diethyl Ester; 2-(Diethoxy-
phosphinylimino)-l,3-Dithiolane; AC 47031; American Cyanamid CL-47031; American
Cyanamide 47031; Cayolan; CL 47031; CL-47031; Cyalane; Cyclic
Ethylene(Diethoxyphosphinothioyl) Dithioimidocarbonate; Cylan; Cyolan; Cyolane
Insecticide; El 47301; ENT 25,830; Imidocarbonic Acid, (Diethoxyphosphinyl)
Dithio-, Cyclic Ethylene Ester; Imidocarbonic Acid, Phosphonodithio-,
P,P-Diethyl Cyclic Ethylene Ester; P,P-DiethyI Cyclic Ethylene Ester of
Phosphonodithioimidocarbonic Acid; Phosphoramidic Acid, l,3-Dithiolan-2-
ylidene-, Diethyl Ester
Chemical Formula: C7HUNO3PS2
Molecular Weight: 255.3
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 239-244.4°F, 115-118°C at 0.001 mmHg
(*Worthing 1979)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
-------
CAS Registry Number: 947-02-4
Page 2 of 4
PHOSFOLAN
SECTION II (continued)
Melting Point: 98.6-113°F, 37-45°C ('Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Worthing 1979)
Appearance and Odor: Colorless to yellow solid ('Worthing 1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Similar to parathion.
Death may result due to respiratory arrest as a result of paralysis of
respiratory muscles and intense bronchoconstriction (*Gosselin 1976). Also
considered a cholinesterase inhibitor (*Soliman 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) Extinguish with dry chemical, carbon dioxide, water, spray, foam,
or fog (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Organophosphorus
Pesticide, n.o.s.) Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material. Wear positive
pressure breathing apparatus and special protective clothing (DOT 1984,
Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) This material may burn but does not ignite readily.
Container may explode in heat of fire (DOT 1984, Guide 55). When heated to
-------
CAS Registry Number: 947-02-4
Page 3 of 4
PHOSFOLAN
SECTION IV (continued)
decomposition, it emits very toxic fumes of oxides of phosphorus, sulfur,
and nitrogen (Sax 1984, p. 2210).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing J979)
Conditions to Avoid: Hydrolyzed by alkalies (*Worthing 1979)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of phosphorus, sulfur, and nitrogen (Sax
1984, p. 2210).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Insecticide (*Farm Chemicals Handbook 1981)
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Keep unnecessary
people away. Do not touch spilled material. Use water spray to reduce
vapors. Take up spills with noncombustible absorbent materials. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move container from spill area. For large spills dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 947-02-4
Page 4 of 4
PHOSFOLAN
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms similar to parathion and include
nausea, vomiting, abdominal cramps, diarrhea, excessive salivation,
headache, giddiness, dizziness, weakness, tightness in the chest, blurring
or dimness of vision, tearing, loss of muscle coordination, slurring of
speech, twitching of muscles, drowsiness, difficulty in breathing,
respiratory rales, and random jerky movements (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific ~ Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 950-10-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MEPHOSFOLAN
CAS Registry Number: 950-10-7
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 177) 1,3-Dithiolane,
2-(Diethoxyphosphinylimino)-4-Methyl-; AC 47470; Cyclic Propylene (Diethoxy-
phosphinyl)Dithioimidocarbonate; Cytrolane; 2-(Diethoxyphosphinylimino)-4-
Methyl-l,3-Dithiolane; P,P-Diethyl Cyclic Propylene Ester of Phosphonodithio-
imidocarbonic Acid; Diethyl (4-Methyl-l,3-Dithiolan-2-ylidene) Phosphoro-
amidate; EI-47470; ENT-25,991
Chemical Formula: C8H16NO3PS2
Molecular Weight: 269.34
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a '2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 248°F, 120°C at 0.001 mmHg (Merck 1983, p. 835)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 57 g/kg at 25°C (Merck 1983, p. 835)
-------
CAS Registry Number: 950-10-7
Page 2 of 4
MEPHOSFOLAN
SECTION II (continued)
Appearance and Odor: Yellow to amber liquid (Merck 1983, p. 835)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organic Phosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Sax 1984, p. 980)
Ingestion: Yes (Sax 1984, p. 980)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic if swallowed or absorbed through the skin (Sax 1984, p. 980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organic Phosphate, Liquid) Use
agent suitable for surrounding fire. Use water in flooding quantities as
fog. Use foam, carbon dioxide, or dry chemical (Student 1981, p. 381).
Special Fire Fighting Procedures: (Non-Specific — Organic Phosphate,
Liquid) Use water spray to absorb vapors. Avoid breathing'vapors. Keep
upwind. Wear self-contained breathing apparatus. Avoid bodily contact
with the material. Wear full protective clothing (Student 1981, p. 381).
Unusual Fire and Explosion Hazards: When heated to decomposition, this
material emits very toxic fumes of nitrogen oxides, phosphorus oxides and
sulfur oxides (Sax 1984, p. 980).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (at neutral pH) (Merck 1983, p. 835)
-------
CAS Registry Number: 950-10-7
Page 3 of 4
MEPHOSFOLAN
SECTION V (continued)
Conditions to Avoid: Hydrolyzed by acid or alkali (Merck 1983, p.
835)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Nitrogen oxides, phosphorus
oxides, and sulfur oxides are emitted when this material is heated to
decomposition (Sax 1984, 980).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is an insecticide and acaricide (Merck 1983, p. 835). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organic Phosphate, Liquid) Use water spray to knock down
vapors. Build dikes to contain material as necessary. Avoid breathing
vapors. Keep upwind. Avoid bodily contact with the material. Downwind
evacuation should be considered (Student 1981, p. 381).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 950-10-7
Page 4 of 4
MEPHOSFOLAN
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Organic Phosphorus
Pesticides) Signs and symptoms include headache, giddiness, nervousness,
blurred vision, weakness, nausea, vomiting, cramps, diarrhea, and
discomfort in the chest. In severe cases there may be convulsions, coma,
loss of reflexes, and loss of sphincter control (Hayes 1982, p. 301).
Emergency and First Aid Procedures: Treat immediately. (Non-Specific --
Organic Phosphorus Pesticide) If this material has been ingested or
inhaled, and the patient is conscious, induce vomiting, give milk or water,
and induce vomiting again. If there has been skin contact, wash contacted
areas with soap and water followed by alcohol. If there has been eye
contact, irrigate with water (Hayes 1982, p. 313).
COMMENT
Sources searched but no information was found:
Clayton and Clayton 1981-82
Weast 1979
Verschueren 1983
Gosselin 1984
Buschel 1983
Farm Chemicals Handbook 1984
-------
CAS Registry Number: 950-37-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHIDATHION
CAS Registry Number: 950-37-8
Synonyms: Phosphorodithioic Acid, O,O-Dimethyl Ester, S-Ester with
4-(Mercaptomethyl)-2-Methoxy-delta(sup2)-l,3,4-Thiadiazolin-5-one; Supracide;
(O,O-Dimethyl) S-(2-Methoxy-delta(sup2)-l,3,4-Thiadiazolin-5-on-4-ylmethyl)
Dithiophosphate; DMTP; ENT 27193; Geigy 13005; Geigy GS-13005; GS 13005;
Medathion; O,O-Dimethyl S (5-Methoxy-l,3,4-Thiadiazolinyl-3-Methyl)
Dithiophosphate; O,O-Dimethyl S-(2-Methoxy-l,3,4,-Thiadiazol-5(4H)-
onyl-(4)-Methyl)Phosphorodithioate; Phosphorodithioic Acid, O,O-Dimethyl Ester,
S-Ester with 4-(Mercaptomethyl)-2-Methoxy-delta(sup2)-l,3,4-
Thiadiazolin-5-one; Phosphorodithioic Acid, S-[(5-Methoxy-2-Oxo-1,3,4-
Thiadiazol-3(2H)-yl)Methyl) O,O-Dimethyl Ester; S-(2,3-Dihydro-5-Methoxy-
2-Oxo-l,3,4-Thiadiazol-3-Methyl) Dimethyl Phosphorothiolothionate;
S-2,3-Dihydro-5-Methoxy-2-Oxo-l,3,4-Thiadiazol-3-ylmethyl O,O-Dimethyl
Phosphorodithioate; S-[(5-Methoxy-2-Oxo-1,3,4-Thiadiazol-3(2H)-yl)Methyl]
O,O-Dimethyl Phosphorodithioate; Somonil; Supracid; Ultracid; Ultracid 40;
Ultracide; Ultracide Ciba-Geigy
Chemical Formula: C6HnN2O4PS3
Molecular Weight: 302.34
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000-(pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.495 at 20°C (Hayes 1982, p. 371)
Vapor Pressure (mmHg): 0.000001 at 20°C (*Worthing 1979)
-------
CAS Registry Number: 950-37-8
Page 2 of 4
METHIDATHION
SECTION II (continued)
Melting Point: 102-104°F, 39-40°C ('Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 240 mg/liter at 25°C ('Worthing 1979)
Appearance and Odor: Colorless crystals ('Worthing 1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific ~ Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Hayes 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): This material is poisonous
to humans. Its toxic effects are by action on the nervous system. Human
volunteers ingesting 0.11 mg/kg/day for 6 weeks had no clinical effects
(Hayes 1982, p. 371).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move container
from fire area if you can do so without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
-------
CAS Registry Number: 950-37-8
Page 3 of 4
METHIDATHION
SECTION IV (continued)
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Fiammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, in neutral or weak acid solution (*Martin
and Worthing 1974)
Conditions to Avoid: Hydrolyzed by alkali (*Worthing 1979)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This mater iU is used as a non-systemic insecticide (*Worthing 1979).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry containers and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 950-37-8
Page 4 of 4
METHIDATHION
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms are similar to parathion
poisoning and may include nausea, vomiting, abdominal cramps, diarrhea,
excessive salivation, headache, dizziness, giddiness, weakness, muscle
twitching, difficult breathing, sensation of tightness of chest, blurring
or dimness of vision, and loss of muscle coordination. Death may occur
from failure of the respiratory center, paralysis of the respiratory
muscles, intense bronchoconstriction, or all three (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 991-42-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- NORBORMIDE
CAS Registry Number: 991-42-4
Synonyms: 5-Norbornene-2,3-Dicarboximide, 5-(alpha-Hydroxy-alpha-2-
Pyridylbenzyl)-7-(alpha-2-Pyridylbenzylidene)-; Compound S-6,999; Raticide;
Raticate; ENT 51,762; Shoxin; McN 1025; McNeil 1025; 4,7-Methano-lH-Isoindole-
l,3(2H)-Dione,3a,4,7,7a-Tetrahydro-5-(Hydroxyphenyl-2-Pyridinylmethyl)-8-
(Phenyl-2-Pyridinylmethylene)-; S 6999; S-6,999
Chemical Formula: CSsH25NsO3
Molecular Weight: 511.55
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
5.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 374-388°F, 190-198°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble unless pH is less than 4
(*Merck 1976); 60 mg/liter at room temperature (*Worthing 1979)
-------
CAS Registry Number: 991-42-4
Page 2 of 3
NORBORMIDE
SECTION II (continued)
Appearance and Odor: Colorless to off-white crystalline powder (*Worthing
1979)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Moderately to highly toxic
to humans. Probable human lethal dose is SO to 500 mg/kg, or 1 teaspoon to
1 pint for a 150 Ib. person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific - Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2069).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes ('Worthing 1979)
-------
CAS Registry Number: 991-42-4
Page 3 of 3
NORBORMIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Alkalies ('Worthing 1979)
Hazardous Decomposition or Byproducts: Nitrogen oxides when heated to
decomposition (Sax 1984, p. 2069).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as a selective rat poison (*Merck 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may cause a transient decrease
in temperature and blood pressure (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 998-30-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRIETHOXYSILANE
CAS Registry Number: 998-30-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 593) Silane, Triethoxy-
Chemical Formula: C6H16O3Si
Molecular Weight: 164.31
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.5 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 270-275°F, 132-135°C (Weast 1983, p. C-516)
Specific Gravity (H2O=1): 0.8745 at 20°C/4°C (Weast 1983, p. C-516)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 998-30-1
Page 2 of 4
TRIETHOXYSILANE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Toxicity is similar to
silanes (Sax 1984, p. 2637). Silanes are moderately irritating to skin,
eyes, and mucous membranes (Sax 1984, p. 2395). Silane compounds are toxic
(Hawley 1981, p. 919).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Poisonous Liquid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site.
Move container from fire area if you can do so without risk. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2637).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 998-30-1
Page 3 of 4
TRIETHOXYSILANE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and fumes (Sax 1984, p. 2637).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Liquid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
-------
CAS Registry Number: 998-30-1
Page 4 of 4
TRIETHOXYSILANE
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 198.0
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 999-81-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLORMEQUAT CHLORIDE
CAS Registry Number: 999-81-5
Synonyms: (2-Chloroethyl)Trimethylammonium Chloride; 60-CS-16; Antywylegacz;
beta-Chloroethyltrimethylammonium Chloride; CCC; CCC Plant Growth Regulant; CE
CE CE; Chlorocholine Chloride; Chlorcholine Chloride; Cycogan; Cycogan Extra;
Cyocel; El 38,555; Ethanaminium, 2-Chloro- N,N,N-Trimethyl-, Chloride;
NCI-C02960; Retacel; Stabilan; Trimethyl-beta- Chloroethylammonium Chloride;
TUR
Chemical Formula: C5H13C12N
Molecular Weight: 158.07
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (cat)
7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statu ny, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 473°F, 245°C; decomposes (Merck 1983, p. 295)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Merck 1983, p. 295)
-------
CAS Registry Number: 999-81-5
Page 2 of 3
CHLORMEQUAT CHLORIDE
SECTION II (continued)
Appearance and Odor: White crystals with a fish-like odor (Merck 1983, p.
295)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Farm Chemicals Handbook 1984,
p. C52)
Skin: Yes (Farm Chemicals Handbook 1984, p. C52)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Inhalation of spray and
prolonged or repeated contact with skin should be avoided (Farm Chemicals
Handbook 1984, p. C52).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Poisonous Solid, n.o.s.) For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 999-81-5
Page 3 of 3
CHLORMEQUAT CHLORIDE
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Plant growth regulator said to be effective for cereal grains, tomatoes,
and peppers (Hawley 1981, p. 302),
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Solid, n.o.s.) Keep unnecessary people away.
Isolate hazard area and deny entry. Stop leak if you can do it without
risk. For small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel, place in clean, dry container and cover, move
from spill area. For large spills: dike far ahead of spill for later
disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCB/ and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 1031-47-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRIAMIPHOS
CAS Registry Number: 1031-47-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 118) Phosphonic Diamide,
p-(5-Amino-3-Phenyl-lH-l,2,4-Triazol-l-yl)-N,N,N',N'-Tetramethyl-;
5-Amino-l-bis(Dimethylamide)Phosphoryl-3-Phenyl-l,2,4-Triazole;
5-Amino-l-(bis(Dimethylamino)Phosphinyl)-3-Phenyl-l,2,4-Triazole;
5-Amino-l-bis(Dimethylamido)Phosphoryl-3-Phenyl-l,2,4-Triazole; ENT 27,223;
5-Amino-3-PhenyI-l,2,4-Triazole-I-yI-N,N,N',N'-Tetramethylphosphodiamide;
5-Amino-3-Phenyl-l,2,4-Triazolyl-l-bis(Dimethylamido)Phosphate;
5-Amino-3-Phenyl-l,2,4-Triazolyl-N,N,N',N'-Tetramethylphosphonamide;
bis(Dimethylamino)-3-Amino-5-Phenyltriazolyl Phosphine Oxide;
3-Phenyl-5-Amino-l,2,4-Triazolyl-(l)-(N,N'-Tetramethyl) Diamidophosphonate;
Triamphos; Wepsin; Wepsyn; Wepsyn 155; WP 155
Chemical Formula: C12H19N6OP
Molecular Weight: 294.34
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 1031-47-6
Page 2 of 4
TRIAMIPHOS
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Solid (Encyc Occupat Health and Safety 1983, p.
1622)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 202)
Skin: Yes (Sax 1984, p. 202)
Ingestion: Yes (Sax 1984, p. 202)
Health Hazards (Acute, Delayed, and Chronic): Triamiphos is an organic
phosphorus insecticide (Encyc Occupat Health and Safety 1983, p. 1622).
Organic phosphorus insecticides are absorbed by the skin, as well as by the
respiratory and gastrointestinal tracts. It is a cholinesterase inhibitor
(Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Triamiphos is listed as an organophosphorus
pesticide (Encyc Occupat Health and Safety 1983, p. 1622). This material
may burn, but does not ignite readily. Extinguish with dry chemical,
carbon dioxide, water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: As for other organophosphorus
pesticides, stay upwind; keep out of low areas. Move containers from fire
area if you can do it without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: As for other organophosphorus
pesticides, containers may explode in heat of fire (DOT 1984, Guide 55).
Heat may cause decomposition and evolution of highly toxic fumes of
-------
CAS Registry Number: 1031-47-6
Page 3 of 4
TRIAMIPHOS
SECTION IV (continued)
nitrogen oxides and phosphorus oxides (Sax 1984, p. 202).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of nitrogen oxides and phosphorus oxides (Sax
1984, p. 202).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used in the control of powdery mildew on apples and ornamentals
(Buchel 1983, p. 258). Product discontinued by U.S. supplier (Farm
Chemicals Handbook 1984, p. C244).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Triamiphos is an organophosphorus pesticide (Encyc Occupat Health and
Safety 1983, p. 1622). Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other non-combustible absorbent
material and place into containers for later disposal. Small dry spills:
with clean shovel place material into clean dry containers and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 1031-47-6
Page 4 of 4
TRIAMIPHOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Triamiphos is an organic phosphorus
insecticide (Encyc Occupat Health and Safety 1983, p. 1622). Symptoms are
secondary to cholinesterase inhibition: headache, giddiness, blurred
vision, nervousness, weakness, nausea, cramps, diarrhea, and discomfort in
the chest. Signs include sweating, tearing, salivation, vomiting, bluing
of the skin, loss of reflexes, loss of sphincter control, convulsions, and
coma (Hayes 1982, p. 302).
Emergency and First Aid Procedures: Triamiphos is an organic phosphorus
insecticide (Encyc Occupat Health and Safety 1983, p. 1622). Move victim
to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Speed in removing material from skin is of
extreme importance. Remove and isolate contaminated clothing and shoes at
the site. Keep victim quiet and maintain normal body temperature. Effects
may be delayed; keep victim under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched, no information found:
Weast 1979
Hawley 1981
Verschueren 1983
Gosselin 1984
NFPA 1984
Weiss 1980
Clayton and Clayton 1981-82
Merck 1983
ACGIH 1983
NIOSH/OSHA 1978
-------
CAS Registry Number: 1066-45-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ TRIMETHYLTIN CHLORIDE
CAS Registry Number: 1066-45-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 627) Stannane,
Chlorotrimethyl-; Chlorotrimethylstannane; Chlorotrimethyltin; M&T Chemicals
1222-45; Trimethylchlorostannane; Trimethylchlorotin; Trimethylstannyl Chloride
Chemical Formula: C3H9ClSn
Molecular Weight: 199.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (rat)
12.6 rag/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 99°F, 37°C (Sax 1984, p. 782)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 1066-45-1
Page 2 of 4
TRIMETHYLTIN CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Tin, organic compounds) TWA 0.1 mg/m3, as tin (NIOSH 1987,
p. 224)
ACGIH TLV: (Tin, organic compounds) TWA 0.1 mg/m3, as tin (skin) (ACGIH
1986-87, p. 31)
IDLH: Not Found
Other Limits Recommended: (Non-Specific — Tin Compounds, Organic) IDLH
200 mg/m5 (NIOSH/OSHA 1978, p. 180). (Tin, organic compounds) NIOSH: 0.1
mg/m3 10-hour TWA, as tin (NIOSH 1987, p. 224)
Routes of Entry: Inhalation: Yes (Non-Specific -- Tin Compounds,
Organic) (NIOSH/OSHA 1978, p. 181)
Skin: Yes (Non-Specific -- Tin Compounds, Organic)
(NIOSH/OSHA 1978, p. 181)
Ingestion: Yes (Non-Specific -- Tin Compounds,
Organic) (NIOSH/OSHA 1978, p. 181)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Tin
Compounds, Organic) The material is an irritant to the skin and
gastrointestinal tract. Contact may specifically damage the following
target organs: central nervous system, eyes, liver, urinary tract, and
skin (NIOSH/OSHA 1978, p. 180).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 782)
-------
CAS Registry Number: 1066-45-1
Page 3 of 4
TRIMETHYLTIN CHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides (Sax 1984, p. 782).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Tin Compounds, Organic)
Inhalation causes headache, lethargy, and irritated eyes. Symptoms of
ingestion include throat irritation, coughing, and abdominal pain. Skin
contact results in burns and sores (NIOSH/OSHA 1978, p. 180).
Emergency and First Aid Procedures: (Non-Specific -- Tin Compounds,
Organic) In case of skin or eye contact wash immediately with large
amounts of water. If ingested, dilute with water and induce vomiting. If
breathing is interrupted, apply artificial respiration or oxygen
(NIOSH/OSHA 1978, p. 180).
COMMENTS
Sources searched but no information found:
Hawley 1981
Weast 1979
Merck 1983
DOT 1984
NFPA 1984
-------
CAS Registry Number: 1066-45-1
Page 4 of 4
TRIMETHYLTIN CHLORIDE
COMMENTS (continued)
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
-------
CAS Registry Number: 1122-60-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ NITROCYCLOHEXANE
CAS Registry Number: 1122-60-7
Synonyms: (SANSS 1983 Synonyms) Cyclohexane, Nitro-
Chemical Formula: C6HnNO2
Molecular Weight: 129.16
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.15 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 401.9°F, 205.5°C at 768 mmHg (Weast 1979, p. C-262)
Specific Gravity (H2O=1): 1.0610 at 20°C/4°C (Weast 1979, p. C-262)
Vapor Pressure (mmHg): Not Found
Melting Point: -29°F, -34°C (Weast 1979, p. C-262)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. C-262)
Appearance and Odor: Colorless liquid (Beilstein 1954, B51 p. 10)
-------
CAS Registry Number: 1122-60-7
Page 2 of 4
NITROCYCLOHEXANE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Poisonous Liquid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Poisonous Liquid,
n.o.s.) Move container from fire area if you can do it without risk. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: 2
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
-------
CAS Registry Number: 1122-60-7
Page 3 of 4
NITROCYCLOHEXANE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Not Found
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poisonous Liquid, n.o.s.) Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Absorb small spills with sand or other noncombustible
absorbent materials. Large spills: dike far ahead of spill for later
disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
CPE GOOD/LIMITED**
Nitrile POOR/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. Remove and isolate contaminated clothing and shoes at the site.
In case of contact with material, immediately flush skin or eyes with
running water for at least 15 minutes. Speed in removing material from
-------
CAS Registry Number: 1122-60-7
Page 4 of 4
NITROCYCLOHEXANE
SECTION IX (continued)
skin is of extreme importance. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 1124-33-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PYRIDINE, 4-NITRO-, 1-OXIDE
CAS Registry Number: 1124-33-0
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 427) 4-Nitro-
Pyridine-N-Oxide
Chemical Formula: C5H4N2O3
Molecular Weight: 140.11
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral (rat)
8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 1124-33-0
Page 2 of 3
PYRIDINE, 4-NITRO-, 1-OXIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2040)
Health Hazards (Acute, Delayed, and Chronic): High toxicity via oral
exposure (Sax 1984, p. 2040).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides (Sax 1984, p. 2040).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2040)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides (Sax 1984, p. 2040).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 1124-33-0
Page 3 of 3
PYRIDINE, 4-NITRO-, 1-OXIDE
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece. self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Hawley 1981
Hayes 1982
Merck 1983
Oilman 1985
Gosselin 1984
Weiss 1980
Student 1981
Encyc Occupat Health and Safety 1983
Buchel 1983
Clayton and Clayton 1981-82
Farm Chemicals Handbook 1984
DOT 1984
CHRIS 1978
Verschueren 1983
-------
CAS Registry Number: 1129-41-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METOLCARB
CAS Registry Number: 1129-41-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 840) Carbamic Acid,
Methyl-, m-Tolyl-Ester; Carbamic Acid, Methyl-, 3-Tolyl Ester; m-Cresyl
Methylcarbamate; m-Cresyl ester of N-Methylcarbamic Acid; Dicresyl; DRC 3341;
Kumiai; Metacrate; 3-Methylphenyl N-Methylcarbamate; MTMC; m-Tolyl
N-Methylcarbamate; 3-Tolyl-N-Methylcarbamate; Tsumacide; Carbamic Acid,
Methyl-, 3-Methylphenyl Ester
Chemical Formula: C9HnNO2
Molecular Weight: 165.21
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.475 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notif cation under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00001 at 25°C (Farm Chemicals Handbook 1984, p.
C236)
Melting Point: 169-171°F, 76-77°C (Farm Chemicals Handbook, 1984, p.
C236)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 1129-41-5
Page 2 of 4
METOLCARB
SECTION II (continued)
Solubility in Water: 2.6 g/liter at 30°C (Farm Chemicals Handbook 1984,
p. C236)
Appearance and Odor: Colorless crystalline solid (Farm Chemicals Handbook
1984, p. C236)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1823)
Skin: Yes (Sax 1984, p. 1823)
Ingestion: Yes (Sax 1984, p. 1823)
Health Hazards (Acute, Delayed, and Chronic): High oral and skin
toxicity, and moderate inhalation toxicity (Sax 1984, p. 1823).
(Non-Specific -- Carbamates) Some carbamates appear to be carcinogenic,
teratogenic, and/or mutagenic (Sax 1984, p. 631). Carbamates are
cholinesterase inhibitors (Hayes 1982, p. 436).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (Farm Chemicals Handbook 1984, p. C236)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Metolcarb is a carbamate insecticide (Buchel 1983,
p. 131). Solid carbamate pesticides may burn but do not ignite readily.
For small fires, use dry chemical, carbon dioxide, water spray, and foam.
For large fires, use water spray, fog or foam. Dike fire control water for
later disposal (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Procedures for carbamate pesticides,
solid, include the following. Stay upwind and keep out of low areas. Wear
positive pressure breathing apparatus and special protective clothing.
Move container from fire area if you can do it without risk. Fight fire
from maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
-------
CAS Registry Number: 1129-41-5
Page 3 of 4
METOLCARB
SECTION IV (continued)
Unusual Fire and Explosion Hazards: As for other solid carbamate
pesticides, container may explode in heat of fire. Fire and runoff from
fire control water may produce irritating or poisonous gases (DOT 1984,
Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1823)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits toxic fumes of nitrogen
oxides when heated to decomposition (Sax 1984, p. 1823).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Metolcarb is an insecticide for the control of rice leafhoppers,
planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies,
bollworms and aphids (Farm Chemicals Handbook 1984, p. C236). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index !985).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). For solid carbamate pesticides,
use the following procedures. For small spills, take up with sand or
other noncombustible absorbent material and place in containers for later
disposal. For small dry spills, with clean shovel place material into
clean, dry container and cover; move container from spill area. For large
spills, dike far ahead of spill for later disposal. Do not touch spilled
material. Use water spray to reduce vapors (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 1129-41-5
Page 4 of 4
METOLCARB
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Metolcarb is a carbamate insecticide
(Buchel 1983, p. 131). Signs and symptoms of poisoning by carbamates are
similar to those for organic phosphorus compounds (Hayes 1982, p. 437).
Symptoms of poisoning by organic phosphorus compounds include headache,
giddiness, nervousness, blurred vision, weakness, nausea, cramps, diarrhea,
and discomfort in the chest. Signs include sweating, myosis, tearing,
salivation and other excessive respiratory tract secretion, vomiting,
cyanosis, uncontrollable muscle twitches followed by muscular weakness,
convulsions, coma, loss of reflexes, and loss of muscular control (Hayes
1982, p. 301).
Emergency and First Aid Procedures: Procedures for carbamate pesticides,
solid, are as follows. Move victim to fresh air and call emergency care.
If not breathing, give artificial respiration. If breathing is difficult,
provide oxygen. Remove and isolate contaminated clothing and shoes at the
site. In case of contact, immediately flush skin or eyes with water for 15
minutes. Speed in removing material from skin is of extreme importance.
Keep victim quiet and maintain normal body temperature. Carefully observe
victim since effects may be delayed (DOT 1984, Guide 55).
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CAS Registry Number: 1303-28-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ARSENIC PENTOXIDE
CAS Registry Number: 1303-28-2
Synonyms: Arsenic (V) Oxide; Arsenic Acid; Arsenic Acid Anhydride; Arsenic
Anhydride; Arsenic Oxide; Arsenic Pentaoxide; Diarsenic Pentoxide; Orthoarsenic
Acid (Weiss 1980, p. 126); Zotox
Chemical Formula: As2Og
Molecular Weight: 229.84
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 5000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II « PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 4.32 (*Clayton and Clayton 1981-82)
Vapor Pressure (mmHg): Not Found
Melting Point: 599°F, 315°C (Hawley 1981, p. 89)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (*Merck 1983)
Appearance and Odor: White (*Hawley 1977), amorphous lumps or powder
(*Merck 1983). Odorless (Weiss 1980, p. 126)
-------
CAS Registry Number: 1303-28-2
Page 2 of 4
ARSENIC PENTOXIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/ms, as arsenic (NIOSH 1987,
P. 54)
ACGIH TLV: 0.2 mg/m5, as arsenic (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: (Arsenic and compounds) NIOSH: ceiling 0.002
mg/m8, 15 minutes, as arsenic (NIOSH 1987, p. 54) (Arsenic and compounds)
NIOSH occupational carcinogen (NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*IARC 1972-85)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7
drops and 1 teaspoonful for a 150-lb. person (*Gosselin 1976). It is
irritating to eyes, nose, and throat (Weiss 1980, p. 126). Chronic
exposure may cause nerve damage to the extremities, alter cellular
composition of the blood, and cause structural changes in blood components
(*Goodman 1980). There is sufficient evidence that inorganic arsenic
compounds are skin and lung carcinogens in humans (*IARC 1972-85).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not flammable (Weiss 1980, p. 126)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (*DOT
1984).
Special Fire Fighting Procedures: Isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*CHRIS 1978)
-------
CAS Registry Number: 1303-28-2
Page 3 of 4
ARSENIC PENTOXIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Will corrode metal and may give off
toxic arsine gas (Weiss 1980, p. 126)
Hazardous Decomposition or Byproducts: Reacts with metal and may give off
toxic arsine gas (Weiss 1980, p. 126).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 126)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a chemical intermediate, as a herbicide, and as an
ingredient in wood preservatives and in glass. Other possible uses are as
an insecticide and soil sterilant (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing dust (see Section III above). Stay upwind; keep out of low
areas. Do not touch spilled material. Absorb small spills with sand or
other noncombustible absorbent material and place into containers for
later disposal. For small dry spills, use clean shovel to place
material in clean, dry container. For large spills, dike far ahead of
spill for later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 1303-28-2
Page 4 of 4
ARSENIC PENTOXIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms usually appear 1/2 to 1 hour
after ingestion, but may be delayed. Symptoms include a sweetish, metallic
taste and garlicky odor of breath; difficulty in swallowing; abdominal
pain; vomiting and diarrhea; dehydration; feeble heart beat; dizziness and
headache; and eventually coma, sometimes convulsions, general paralysis,
and death (*Gosselin 1984).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. Remove contaminated clothing and shoes. In case
of contact with material, immediately flush skin or eyes with running water
for at least 15 minutes (*DOT 1984). In case of ingestion, induce
vomiting; give plenty of lime water, milk, or raw egg (Weiss 1980, p. 126).
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CAS Registry Number: 1306-19-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CADMIUM OXIDE
CAS Registry Number: 1306-19-0
Synonyms: Cadmium Fume; Cadmium Monoxide; Cadmium Oxide Fume; NCI-CO2551
Chemical Formula: CdO
Molecular Weight: 128.40
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.5 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Cadmium Compounds category
SECTION f -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Crystalline form: 8.15 (*Weast 1979);
Amorphous form: 6.95 (Weast 1979, p. B-103)
Vapor Pressure (mmHg): 1 at 1000°C (*Sax 1975)
Melting Point: Greater than 2732°F, greater than 1500°C (Weast 1979, p.
B-103)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1979)
Appearance and Odor: Brown crystals or brown amorphous powder (*Weast
1979)
-------
CAS Registry Number: 1306-19-0
Page 2 of 4
CADMIUM OXIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Cadmium fume/cadmium oxide fume) TWA 0.1 mg/m8, as cadmium;
Ceiling 0.3 mg/m3, as cadmium (NIOSH 1987, p. 68)
ACGIH TLV: (Fume) Ceiling 0.05 mg/m3, as cadmium; (Production) TWA 0.05
mg/ms, as cadmium (ACGIH 1986-87, p. 12)
IDLH: (Cadmium fume/cadmium oxide fume) 40 mg/m3, as cadmium (NIOSH 1985,
p. 68)
Other Limits Recommended: NIOSH: lowest feasible limit (NIOSH 1987, p. 68)
NIOSH occupational carcinogen (NIOSH 1987, p. 68)
Routes of Entry: Inhalation: Yes (*IARC 1972-1985)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 613)
Health Hazards (Acute, Delayed, and Chronic): The lethal inhalation dose
of cadmium oxide in humans is 2,500 mg/m3 for a 1 minute exposure (*IARC
1972-1985). Lethal exposure has been established at 50 mg (cadmium)/m3 for
1 hour for cadmium oxide dust and 1/2 hour for the fume (*Casarett 1975).
These concentrations may be inhaled without sufficient discomfort to warn
worker of exposure (*Sax 1984, p. 612). Inhalation may cause acute
tracheobronchitis, pneumonitis, and pulmonary edema. Exposure can cause
kidney and lung damage (*Encyc Occupat Health and Safety 1981). Acute
exposure by inhalation may cause death by anoxia. The lowest human toxic
inhalation concentration is 8.630 mg/ms/5 hours for the fume (*NIOSH/RTECS
1985).
Medical Conditions Generally Aggravated by Exposure: Persons with
respiratory disorders should be excluded from contact with this material
(*Encyc Occupat Health and Safety 1971).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: (Non-Specific — Cadmium Compounds) This material may
burn but does not ignite readily (DOT 1984, Guide 53).
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Cadmium Compounds) Extinguish
with dry chemical, carbon dioxide, water fog, spray, or foam (DOT 1984,
Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Cadmium Compounds)
Wear self-contained breathing apparatus and full protective clothing. Move
container from fire if you can do so without risk (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of cadmium (Sax 1984, p. 613). (Non-Specific -- Cadmium
Compounds) Fire may produce irritating or poisonous gases. Runoff from
fire control or dilution water may cause pollution (DOT 1984, Guide 53).
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CAS Registry Number: 1306-19-0
Page 3 of 4
CADMIUM OXIDE
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Oxides of cadmium react explosively
with magnesium when heated (*NFPA 1978).
Hazardous Decomposition or Byproducts: Toxic fumes may form in a fire
(*CHRIS 1978). When heated to decomposition, it emits toxic fumes of
cadmium (Sax 1984, p. 613).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Cadmium oxide is used as an electroplating chemical and in the manufacture
of cadmium electrodes. It is a component of silver alloys, phosphors,
semiconductors, glass and ceramic glazes (*SRI). It was formerly used by
veterinarians to kill worms and parasites (*Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
If dust is released in a hazardous concentration: (1) remove all ignition
sources; (2) ventilate area of release; and (3) collect released material
and place in sealed containers in secured sanitary landfill (*NIOSH/OSHA
1981). (Non-Specific -- Cadmium Compounds) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind, keep out of low areas.
If pollution of water occurs, notify proper authorities. Do not touch
spilled material; stop leak if you can do so without risk. Absorb
small spills with sand or other noncombustible absorbent material and
place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
container from spill area. Dike large spills far ahead for later
disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
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CAS Registry Number: 1306-19-0
Page 4 of 4
CADMIUM OXIDE
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1306-19-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
CADMIUM OXIDE
(1306-19-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless, amorphous powder; brown or red crystals.
Odor - None.
Commercial Form - Silver-white or yellow-brown to brown solid.
Uses - Catalyst for organic reactions; electroplating; manufacture of
electrodes, silver alloys, semiconductors, glass, and ceramic glazes.
Other Names - Cadmium fume, cadmium monoxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
EDTA.
Signs and Symptoms of Acute Cadmium Oxide Exposure:
Warning: Effects may be delayed for hours. Caution is advised.
The following signs and symptoms may be noted following exposure to cadmium
oxide: cough, dyspnea (shortness of breath), dry mouth or increased
salivation, abdominal pain, nausea, vomiting, bronchitis, and chest pain.
Pulmonary edema may develop. Vertigo (dizziness), fever, and profuse sweating
are common. Victims may collapse.
-------
EFATG
CAS Registry Number: 1306-19-0
Page 2 of 3
CADMIUM OXIDE
Emergency Life-Support Procedures:
Acute exposure to cadmium oxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to cadmium oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
•
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EFATG
CAS Registry Number: 1306-19-0
Page 3 of 3
CADMIUM OXIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of .cadmium oxide is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of cadmium oxide may result in sudden loss of
consciousness. Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 1314-56-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHORUS PENTOXIDE
CAS Registry Number: 1314-56-3
Synonyms: Diphosphorus Pentaoxide; Diphosphorus Pentoxide; Phosphoric Acid
Anhydride; Phosphoric Acid, Anhydrous; Phosphoric Anhydride; Phosphoric Oxide;
Phosphoric Pentoxide; Phosphorus Oxide; Phosphorus Pentaoxide;
Phosphorus(V)Oxide; Phosphorus, Oxide, Pent-
Chemical Formula: P2O5
Molecular Weight: 141.96
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.061 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Sublimes at 572°F, 300°C (Weast 1983, p. B-119)
Specific Gravity (H2O=1): 2.39 (*Weast 1979)
Vapor Pressure (mmHg): 1 at 384°C (Weast 1983, p. D-197)
Melting Point: 340°C (Merck 1983, p. 7247)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: White powdery crystals (*Weast 1979)
-------
CAS Registry Number: 1314-56-3
Page 2 of 4
PHOSPHORUS PENTOXIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Hygienic standard recommended in AIHA Guide is
1 mg (phosphorus pentoxide)/m3 of air (*Clayton and Clayton 1981-82).
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Powder and fumes in the air
are irritating to eyes and the respiratory tract (*Grant 1974). Particles
in contact with eye react vigorously and even a small amount may cause
permanent burns. Contact with the skin will cause severe burns. Ingestion
will damage the gastrointestinal tract (*Rumack 1975 to Present).
Corrosive to skin, mucous membranes and eyes (Merck 1983, p. 1061).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Flammable (Merck 1983, p. 1061)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Does not support combustion (Merck 1983, p. 1061).
Do not get water inside container. For small fires, use dry chemical or
carbon dioxide. For large fires, flood fire area with water from a
distance. Do not get solid stream of water on spilled material. Spray
cooling water on containers that are exposed to flames until well after
fire is out (DOT 1984, Guide 39).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Keep combustibles away from
spilled material (DOT 1984, Guide 39).
Unusual Fire and Explosion Hazards: Reacts violently with water to evolve
heat (Hawley 1981, p. 809). Flammable poisonous gases may accumulate in
tanks and hopper cars (DOT 1984 Guide 39). Phosphorus pentoxide reacts
violently with the following: ammonia, hydrofluoric acid, oxygen
difluoride, potassium, sodium, propargyl alcohol, calcium oxide, sodium
hydroxide and chlorine trifluoride. A violent explosion occurs if a
solution of perchloric acid in chloroform is poured over phosphorus
pentoxide (*NFPA 1978).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 1314-56-3
Page 3 of 4
PHOSPHORUS PENTOXIDE
SECTION V « REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Hawley 1977)
Conditions to Avoid: Readily absorbs moisture from air to form meta-,
pryo-, or orthophosphoric acid (*Hawley 1977).
Incompatibility (Materials to Avoid): Formic acid, hydrogen fluoride,
inorganic bases, metals, oxidants, water (Sax 1984, p. 2224). Phosphorus
pentoxide reacts violently with the following: ammonia, hydrofluoric acid,
oxygen difluoride, potassium, sodium, propargyl alcohol, calcium oxide,
sodium hydroxide and chlorine trifluoride. A violent explosion occurs if a
solution of perchloric acid in chloroform is poured over phosphorus
pentoxide (*NFPA 1978).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Drying and dehydrating agent; condensing agent in organic synthesis (*Merck
1976). Used in the preparation of acrylate esters, surfactants, sugar
refining, medicine, fire extinguishing, and special glasses (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away. Stay upwind. Keep out of low areas.
Ventilate closed spaces before entering them. Stop leak if possible without
risk. Do not touch spilled material. Use water spray to reduce vapors,
but do not put water on leak or spill. Keep combustibles away from spilled
material. Dike spilled area and keep water away from spill. Clean up
requires supervision by an expert (DOT 1985, Guide 39).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 1314-56-3
Page 4 of 4
PHOSPHORUS PENTOXIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1314-56-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHOSPHORUS PENTOXIDE
(1314-56-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystalline powder.
Commercial Form - 98% pure powder in glass bottles, cans, or drums.
Uses - Drying and dehydrating, organic syntheses, sugar refining,
pharmaceutical and glass manufacturing, flame retardants, fire extinguishing.
Materials to Avoid - Alkali, metals, oxidizers, water (except for use in
emergency life support).
Caution: Reacts violently with water to evolve heat and generate aqueous
phosphoric acid.
Other Names - Diphosphorus pentaoxide, phosphoric acid anhydride, phosphoric
oxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, dopamine, norepinephrine.
Signs and Symptoms of Acute Phosphorus Pentoxide Exposure:
Signs and symptoms of acute exposure to phosphorus pentoxide may include
severe burns, pain, shock, intense thirst, nausea, vomiting, diarrhea, severe
abdominal pain, and "smoking stools." The breath and feces may have a garlicky
odor. A symptom-free period of several days may follow.
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EFATG
CAS Registry Number: 1314-56-3
Page 2 of 3
PHOSPHORUS PENTOXIDE
Exposure to phosphorus pentoxide may also result in bloody vomitus and
diarrhea, jaundice, liver enlargement with tenderness, renal damage, hematuria
(bloody urine), and either oliguria (scanty urination) or anuria (suppression
of urine formation). Headache, convulsions, delirium, coma, cardiac
arrhythmias, and cardiovascular collapse may occur.
If phosphorus pentoxide contacts the eyes, severe irritation and burns,
blepharospasm (spasmodic winking), lacrimation (tearing), and photophobia
(heightened sensitivity to light) may occur. Eye contact may lead to a total
destruction of the eyes. Victims may experience spontaneous hemorrhaging of
phosphorus pentoxide-contaminated skin and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to phosphorus pentoxide may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosphorus pentoxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosphorus pentoxide.
-------
EFATG
CAS Registry Number: 1314-56-3
Page 3 of 3
PHOSPHORUS PENTOXIDE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. Brush nonadherent phosphorus pentoxide from skin areas, then flush skin
with water. Immerse exposed skin areas in water or cover with a wet
dressing.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
AT LEAST 15 MINUTES. Keep exposed eyes covered with wet compresses.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
4. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
5. Ambulate (walk) and give water to the victims.
6. RUSH to a health care facility.
-------
CAS Registry Number: 1314-62-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- VANADIUM PENTOXIDE
CAS Registry Number: 1314-62-1
Synonyms: CI 77938; Divanadium Pentaoxide; Divanadium Pentoxide; Vanadic
Anhydride; Vanadium Oxide; Vanadium Pentaoxide
Chemical Formula: V2O5
Molecular Weight: 181.90
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 3182°F, 1750°C (decomposition) (*NIOSH/OSHA 1981)
Specific Gravity (H2O=1): 3.357 at 18°C (*Hawley 1981)
Vapor Pressure (mmHg): Approximately 0 at 20°C, 68°F (*NIOSH/OSHA 1981)
Melting Point: 1274°F, 690°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 1 g in 125 ml (*Merck 1983)
Appearance and Odor: Vanadium pentoxide exists as a yellow-orange powder,
dark gray flakes, or yellow to rust brown crystals (*NIOSH/OSHA 1981;
*Merck 1983). It is odorless (*CHRIS 1978)
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CAS Registry Number: 1314-62-1
Page 2 of 3
VANADIUM PENTOXIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Ceiling 0.5 mg/m8, as vanadium (dust); Ceiling 0,1 mg/m3,
as vanadium (fume) (NIOSH/OSHA 1978, p. 188)
ACGIH TLV: TWA 0.05 mg/m3 (respirable dust and fume) (ACGIH 1985,
P. 33)
IDLH: 70 mg/m3 (NIOSH/OSHA 1978, p. 188)
Other Limits Recommended: (Dust and fume) NIOSH: 0.05 mg/m3 15-minute
ceiling (NIOSH 1987, p.234)
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2718)
Skin: Yes (Merck 1983, p. 1418)
Ingestion: Yes (Sax 1984, p. 2718)
Health Hazards (Acute, Delayed, and Chronic): Probable oral lethal dose
for humans is between 5 and 50 mg/kg or between 7 drops and 1 teaspoonful
for a 70 kg (150 Ib.) person (*Gosselin 1984). Toxicity is about the same
magnitude as pentavalent arsenic (Gosselin 1984, p. 11-148).
Medical Conditions Generally Aggravated by Exposure: Chronic respiratory
disease (*Encyc Occupat Health and Safety 1983).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (Weiss 1980, p. 909)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam. Move container
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Container may explode in heat of fire
(DOT 1984, Guide 55) When heated to decomposition, it emits acrid smoke
and fumes of vanadium oxides (Sax 1984, p. 2718). Material is not
flammable but it may increase the intensity of the fire when in contact
with combustible materials (Weiss 1980, p. 909).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 1314-62-1
Page 3 of 3
VANADIUM PENTOXIDE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 909)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Chlorine trifluoride; lithium;
peroxyformic acid; and calcium, sulfur, water complexes (Sax 1984, p. 2718)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and fumes of vanadium oxides (Sax 1984, p. 2718).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 909)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
As catalyst in the oxidation of sulfur dioxide to sulfur trioxide, alcohol
to acetaldehyde, etc.; for the manufacture of yellow glass; inhibiting
ultraviolet light transmission in glass; depolarizer; as developer in
photography; in form of ammonium vanadate as mordant in dyeing and printing
fabrics and in manufacture of aniline black (Merck 1983, p. 1418).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe dust. In case of contact, immediately flush skin or
eyes with water (see Section III above). Do not touch spilled
materials; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small
dry spills: with clean shovel place material into clean, dry container
and cover; move containers from spill area. Large spills: dike far ahead
of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1314-62-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
VANADIUM PENTOXIDE
(1314-62-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Yellow to rust-brown crystals, yellow-orange powder, or dark gray
flakes.
Odor - None.
Commercial Form - 98 to 99% pure solid shipped in drums or multi-walled paper
sacks.
Uses - Dyeing textiles, oxidation catalyst, manufacture of specialty glass,
developer in photography, depolarizer.
Other Names - Divanadium pentoxide, vanadic anhydride.
Personal Protective Equ,<»nient: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, normal saline, DSW, Ringer's
lactate, dimercaprol (BAL), EDTA.
Signs and Symptoms of Acute Vanadium Pentoxide Exposure:
Acute exposure to vanadium pentoxide may result in pulmonary irritation,
bronchospasm, hemoptysis (coughing up of blood), pulmonary edema, emphysema,
and pneumonia. Gastrointestinal effects may include nausea, abdominal
cramping, diarrhea, anorexia, and black stools. Headache, dry mouth,
dizziness, nervousness, insomnia, and tremor may be found.
-------
EFATG
CAS Registry Number: 1314-62-1
Page 2 of 3
VANADIUM PENTOXIDE
Vanadium pentoxide is irritating to the skin, eyes, and mucous membranes.
Contact may result in a green staining of the tongue and skin. Blindness and
epistaxis (bloody nose) are further complications.
Emergency Life-Support Procedures:
Acute exposure to vanadium pentoxide may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to vanadium pentoxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to vanadium pentoxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
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EFATG
CAS Registry Number: 1314-62-1
Page 3 of 3
VANADIUM PENTOXIDE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of vanadium pentoxide is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no sign of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 5.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. Transport to a health care facility.
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CAS Registry Number: 1314-84-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ZINC PHOSPHIDE
CAS Registry Number: 1314-84-7
Synonyms: Blue-ox; Delusal; Kilrat; Mous-con; Phosvin; Rumetan; Stutox;
Trizinc Diphosphide; Wuehlmaus-Koeder; Wuehlmaustod Arvikol; Zinc Phosphide
(Zn3P2); Zinc-tox; ZP
Chemical Formula: PjZng
Molecular Weight: 258.09
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 12 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 2012°F, 1100°C (*Merck 1983)
Specific Gravity (H2O=1): 4.55 (*Merck 1983)
Vapor Pressure (mmHg): Not Found
Melting Point: 788°F, 420°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Weast 1979, p. B-143); insoluble (Merck
1983, p. 1457)
Appearance and Odor: Dark gray crystals, lustrous or dull powder with a
faint phosphorus odor (*Merck 1983); dark gray granular solid (Student
1984, p. 541)
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CAS Registry Number: 1314-84-7
Page 2 of 4
ZINC PHOSPHIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes ('Arena 1974)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This compound is very
caustic when ingested. Zinc phosphide reacts with water and acid in the
stomach and causes severe irritation (*Doull 1980). The probable oral
lethal dose is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 70 kg
(150 Ib.) person. Most patients die after about 30 hours from peripheral
vascular collapse secondary to the compound's direct effects. Extensive
liver damage and kidney damage can also occur. Ingestion of 4-5 grams has
produced death in human adults, but also doses of 25 to 50 grams have been
survived (*Gosselin 1976). The lowest oral lethal dose reported for women
is 80 mg/kg ('NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not use water or foam. Small fires, use dry
chemical, soda ash or lime. Large fires, withdraw from area and let burn
(DOT 1984, Guide 41). Do not use any agent with an acid reaction (i.e.,
carbon dioxide or halogenated agents) as phosphine will be liberated
(*CHRIS 1978).
Special Fire Fighting Procedures: Wear boots, protective gloves, and
goggles. Wear self-contained breathing apparatus when fighting fires
involving this material (Student 1981, p. 541). Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Move container from fire area if you can do so without risk (DOT
1984, Guide 41).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of phosphorus and zinc oxides (Sax 1984, p. 2756).
Irritating oxides of phosphorus may be formed in fires (*CHRIS 1978). May
ignite in presence of moisture. Contact with water produces flammable gas.
Runoff to sewer may create fire or explosion hazard (DOT 1984, Guide 41).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 1314-84-7
Page 3 of 4
ZINC PHOSPHIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Farm Chemicals Handbook 1984)
Conditions to Avoid: May ignite in the presence of moisture, or
evolve flammable gas (*DOT 1984). Stable unless exposed to moisture;
toxic phosphine gas may then be released and collected in closed spaces
(Sax 1984, p. 2756).
Incompatibility (Materials to Avoid): Reacts violently with concentrated
sulfuric acid, nitric acid, and other oxidizing agents (*Merck 1983).
Reacts with hydrochloric acid or sulfuric acid with the evolution of
spontaneously flammable phosphine (Merck 1983, p. 1457).
Hazardous Decomposition or Byproducts: Decomposed slowly by water giving
off phosphine, a flammable poison gas (Student 1981, p. 541). When heated
to decomposition, it emits toxic fumes of oxides of phosphorus and zinc
(Sax 1984, p. 2756).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 935)
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
It is a rodenticide (Encyc Occupat Health and Safety 1983, p. 2341) used in
the manufacture of rat and mouse poison (*Merck 1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not use water. Keep sparks, flames, and other sources of ignition away.
Keep material out of water sources and sewers. Keep material dry. Avoid
breathing dusts and fumes from burning material. Keep upwind. Avoid
bodily contact with the material. Do not handle broken packages without
protective equipment. Wash away any material which may have contacted
the body with copious amounts of water or soap and water. For a land
spill, dig a pit, pond, lagoon, or holding area to contain liquid or solid
material. For water spill, neutralize with agricultural lime (slaked
lime), crushed limestone, or sodium bicarbonate. Use mechanical dredges
or lifts to remove immobilized wastes of pollutants and precipitates
(Student 1981, p. 541). Small dry spills: with clean shovel place material
into clean, dry container and cover; move containers from spill area.
Large spills: dike spill for later disposal. Cover powder spill with
plastic sheet or tarp to minimize spreading. Clean up only under
supervision of an expert (DOT 1984, Guide 41).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
-------
CAS Registry Number: 1314-84-7
Page 4 of 4
ZINC PHOSPHIDE
SECTION VIII (continued)
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Butyl/Neoprene GOOD/LIMITED**
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
Viton GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Earliest symptoms of oral ingestion
include nausea, abdominal pain, tightness in chest, excitement, agitation
and chills. Early labored breathing, shock, halted urinary output,
metabolic acidosis, muscle cramps and convulsions are grave prognostic
signs (*Gosselin 1976). Inhalation of zinc phosphide dust is followed in
several hours by vomiting, diarrhea, bluing of skin, rapid pulse, fever and
shock. The breath smells of phosphine (*Arena 1974). The compound is very
caustic and may cause closing of the esophagus (*Rumack 1975 to Present).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin and eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature (DOT 1984, Guide
41).
-------
CAS Registry Number: 1327-53-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ARSENOUS OXIDE
CAS Registry Number: 1327-53-3
Synonyms: Arsenic Trioxide; Arsenic (III) Oxide; Arsenic Oxide; Arsenic
Sesquioxide; Arsenicum Album; Arsenious Acid; Arsenious Oxide; Arsenious
Trioxide; Arsenite; Arsenolite; Arsenous Acid; Arsenous Acid Anhydride;
Arsenous Anhydride; Arsenous Oxide Anhydride; Arsodent; Claudetite; Crude
Arsenic; Diarsenic Trioxide; White Arsenic
Chemical Formula: As2O3
Molecular Weight: 197.8
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(man) 1.43 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 5000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 869°F, 465°C (*Merck 1976)
Specific Gravity (H2O=1): 3.738 (amorphous or vitreous); 3.865
(arsenolite); 4.15 (claudetite) (Weast 1983, p. B-71)
Vapor Pressure (mmHg): 66.1 at 312°C ('Worthing 1979)
Melting Point: 594.1°F, 312.3°C; 379°F, 193°C sublimes (arsenolite and
claudetite) (Weast 1983, p. B-71)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Sparingly soluble in cold water. Soluble in 15
parts boiling water (*Merck 1976).
-------
CAS Registry Number: 1327-53-3
Page 2 of 4
ARSENOUS OXIDE
SECTION II (continued)
Appearance and Odor: White or transparent, glassy, amorphous lumps or
crystalline powder (*Merck 1976); odorless (*Hawley 1977).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Arsenic and coumpounds) TWA 0.01 mg/m3, as arsenic (NIOSH
1987, p. 54)
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: (Arsenic trioxide production) Industrial
substance suspect of carcinogenic potential for man (ACGIH 1986-87, p. 10)
Routes of Entry: Inhalation: Yes (*Friberg 1979)
Skin: Not Found
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): Material is considered
super toxic; probable oral lethal dose (human) is less than 5 mg/kg, i.e.,
a taste (less than 7 drops) for a 70kg (150 Ib.) person. Material causes
acute gastrointestinal and central nervous system symptoms. Renal and
hepatic damage have also been observed (*Gosselin 1976). Chronic exposure
to material has led to nasal septum perforation, dermatological symptoms
(lesions, necrosis, etc.) and an increase in the incidence of lung and
lymphatic cancers (*Gosselin 1976, *Clayton and Clayton 1981-82, *Venugopal
1978, *ACGIH 1981). Appreciable exposure to respiratory irritant promoters
such as metal oxide fumes elicits a carcinogenic response from arsenic
trioxide (*Clayton and Clayton 1981-82).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (*CHRIS 1980)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish fire using agent suitable for type of
surrounding fire (material itself does not burn or burns with difficulty).
Use water in flooding quantities as fog. Use foam, carbon dioxide or dry
chemical (*Student 1981).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
(*Student 1981).
Unusual Fire and Explosion Hazards: Toxic fumes of arsenic trioxide and
arsine may be formed in fire situations (*CHRIS 1980).
-------
CAS Registry Number: 1327-53-3
Page 3 of 4
ARSENOUS OXIDE
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: It is stable in air but slowly oxidizes in acid
media (*Worthing 1979).
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Sodium chlorate; fluorine; chlorine
trifluoride; chromic oxide; aluminum chloride; phosphorus pentoxide;
hydrogen fluoride; oxygen difluoride (*NFPA 1978); tannic acid; infusion
cinchona and other vegetable astringent infusions and decoctions; iron in
solution (*Merck 1976).
Hazardous Decomposition or Byproducts: Toxic fumes of arsenic trioxide
and arsine may be formed in fire situations (*CHRIS 1980). Contact with
halide acids will form toxic volatile halides. Reduction in acid solutions
will form arsine (*AOAC 1965). Arsenic trioxide and excess zinc filings
will explode on heating (*Bretherick 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORM \TION
Primary material for all arsenic compounds (*Merck 1976). It is an
intermediate for insecticides, herbicides and fungicides. The material is
used as a wood preservative and a decoloring and refining agent in glass
manufacture. It is also used in Pharmaceuticals and in the purification of
synthetic gas (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing dusts, and fumes from burning materials. Keep upwind.
Avoid bodily contact with the material. Do not handle broken packages
without protective equipment. Wash away any material which may have
contacted the body with copious amounts of water or soap and water
(*Student 1981).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
-------
CAS Registry Number: 1327-53-3
Page 4 of 4
ARSENOUS OXIDE
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1327-53-3
Page 1 of 4
Emergency First Aid Treatment Guide
for
ARSENOUS OXIDE
(1327-53-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White or transparent glossy amorphous lumps or crystalline
powder.
Odor - None.
Commercial Form - 95 to 99% pure solid.
Uses - Primary material for arsenic compounds and textile mordants; manufacture
of pesticides, Pharmaceuticals, wood preservatives, enamels, and glass;
preservation of hides; purification of synthetic gas.
Other Names - Arsenic sesquioxide, arsenic trioxide, Arsenite, arsenous acid,
arsenous acid anhydride, Arsodent, Claudelite, crude arsenic, diarsenic
trioxide, white arsenic.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
dopamine, norepinephrine, sodium bicarbonate, dimercaprol, penicillamine,
isoproterenol.
-------
EFATG
CAS Registry Number: 1327-53-3
Page 2 of 4
ARSENOUS OXIDE
Signs and Symptoms of Acute Arsenous Oxide Exposure:
Warning: Effects usually appear within 30 minutes of exposure but may be
delayed for several hours. Caution is advised.
Hypotension (low blood pressure), tachycardia (rapid heart rate), dehydration,
intense thirst, difficulty swallowing, vomiting, abdominal pain, and diarrhea
are among the first signs and symptoms noticed following acute arsenous oxide
exposure. Headache, conjunctivitis (red, inflamed eyes), runny nose, and
lacrimation (tearing) are also common. Garlic odor of breath and feces may be
noted.
Cardiovascular effects include shock, tachycardia (rapid heart rate),
ventricular fibrillation, and other cardiac abnormalities. Pulmonary edema may
occur. Altered mental status, seizures, and delirium are further complications
of arsenous oxide exposure. Intense muscle cramping is common. Exposure to
airborne dust is generally accompanied by irritation of exposed skin, eyes, and
mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to arsenous oxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to arsenous oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
-------
EFATG
CAS Registry Number: 1327-53-3
Page 3 of 4
ARSENOUS OXIDE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to arsenous oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. RUSH to a health care facility!
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of arsenous oxide is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of arsenous oxide may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 5.
-------
EFATG
CAS Registry Number: 1327-53-3
Page 4 of 4
ARSENOUS OXIDE
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
-------
CAS Registry Number: 1397-94-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ ANTIMYCIN A
CAS Registry Number: 1397-94-0
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 430): Antipiricullin;
Virosin
Chemical Formula: C28H40N2O9
Molecular Weight: 548.70
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 1.8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 149°C (Merck, 1983, p. 733)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 1397-94-0
Page 2 of 4
ANTIMYCIN A
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 307)
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 1397-94-0
Page 3 of 4
ANTIMYCIN A
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of oxides of nitrogen (Sax 1984, p. 307).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Specific uses for Antimycin A were not found, however, Antimycin Al, and
Antimycin A3 are reported to be antibiotic substances produced by
Streptomyces for use as a fungicide, possible insecticide and miticide
(Merck 1983, pp. 104-105, Hawley 1981, p. 82). Only registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
!a>er disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Neoprene GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 1397-94-0
Page 4 of 4
ANTIMYCIN A
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh' air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Hayes 1982
Physicians' Desk Reference 1985
-------
CAS Registry Number: 1420-07-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DINOTERB
CAS Registry Number: 1420-07-1
Synonyms: 2,4-Dinitro-6-tert-Butylphenol; 2-(l,l-Dimethylethyl)-4,6-
Dinitrophenol; 2-tert-Butyl-4,6-Dinitrophenol; Dinoterbe; DNTBP; Herbogil;
Phenol, 2-(l,l-Dimethylethyl)-4,6-Dinitro-; Phenol, 2-tert-Butyl-4,6-Dinitro-;
Phenol, o-t-Butyl-4,6-Dinitro-; Stirpan Forte; Veraline Creme
Chemical Formula: C10H12N2O5
Molecular Weight: 240.24
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 198fc
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes 01 No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 259°F, 126°C (*Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (*Worthing 1979).
Appearance and Odor: Yellow solid (*Worthing 1979).
-------
CAS Registry Number: 1420-07-1
Page 2 of 3
DINOTERB
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Dinitro-o-Cresol)
(ACGIH 1980, p. 152-153)
Skin: Yes (Non-Specific ~ Dinitro-o-Cresol) (ACGIH
1980, p. 152-153)
Ingestion: Yes (Non-Specific -- Dinitro-o-Cresol)
(ACGIH 1980, p. 152-153)
Health Hazards (Acute, Delayed, and Chronic): This compound is toxic by
all routes of exposure. The dangerous single oral dose of dinitro-o-
cresol, a structurally similar compound (*Rumack 1975 to Present), is
estimated to be about 29 mg/kg (Hayes 1982, p. 469).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specif ic -- Dinitro-o-cresol) Use dry
chemical, carbon dioxide, water spray, or foam for small fires, and water
spray, fog, or foam for large fires. Move container from fire area if
possible (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Dinitro-o-cresol)
Isolate hazard area, stay upwind, and keep out of low areas. Wear
self-contained breathing apparatus and full protective clothing (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
toxic nitrogen oxide fumes (Sax 1984, p. 1160).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 1420-07-1
Page 3 of 3
DINOTERB
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic nitrogen oxide fumes (Sax 1984, p. 1160).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This compound is a herbicide (Farm Chemicals Handbook 1984, p. C82) and a
rodenticide (*Tsubura and Kato 1974).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). (Non-Specific -- Dinitro-o-Cresol)
Do not touch spilled material; stop source of spill or leak if it can be
done without risk. Take up small spills with sand or other noncombustible
absorbent material and place into containers for later disposal. Small
dry spills: with clean shovel place material into clean, dry container and
cover. Remove from spill area for later removal. Dike far ahead of spill
for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of poisoning are similar to
other dinitrophenols (*Rumack 1975 to Present) and may include nausea,
gastric distress, restlessness, sensation of heat, flushed skin, sweating,
thirst, deep and rapid breathing, rapid heart rate, fever, and lack of
oxygen to tissues (blueness of skin) (Hayes 1982, p. 469).
Emergency and First Aid Procedures: (Non-Specific — Dinitro-o-Cresol)
Move victim to fresh air; call emergency medical care. Remove and isolate
contaminated shoes and clothing at the site. In case of contact with
material, immediately flush skin or eyes with running water for at least 15
minutes (DOT 1984, Guide 53).
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CAS Registry Number: 1464-53-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIEPOXYBUTANE
CAS Registry Number: 1464-53-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 757) 1,2:3,4-
Diepoxybutane; l,l'-Bi(Ethylene Oxide); Bioxiran; Bioxirane; 2,2'-Bioxirane;
Butadiene Dioxide; 2,4-Diepoxybutane; Dioxybutadiene; ENT-26592; Erythritol
Anhydride; Threitol, l,2:3,4-Dianhydro-
Chemical Formula: C4H6O2
Molecular Weight: 86.10
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.317 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 280°F, 138°C at 1 atm (Merck 1983, p. 531)
Specific Gravity (H2O=1): 1.113 at 18°C/4°C (Merck 1983, p. 531)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Weast 1980, p. C-219); hydrolyzes to
erythritol (Merck 1983, p. 531)
Appearance and Odor: Colorless liquid (Sax 1984, p. 429)
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CAS Registry Number: 1464-53-5
Page 2 of 3
DIEPOXYBUTANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 19S4, p. 429)
Skin: Yes (Sax 1984, p. 429)
Ingestion: Yes (Sax 1984, p. 429)
Health Hazards (Acute, Delayed, and Chronic): Severe skin and eye
irritant (Sax 1984, p. 429). Accidental minor exposure caused swelling of
the eyelids, upper respiratory tract irritation and painful eye irritation
6 hours after exposure (Encyc Occupat Health and Safety 1983, p. 772).
NOTE: The dl- and meso-forms (CAS Registry Numbers 298-18-0 and 564-00-1,
respectively) as well as the L(-) form (CAS Registry Number 30031-64-2)
have all been determined to be positive animal carcinogens (NIOSH/RTECS
1983, Volume 1, p. 757).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
acrid smoke and irritating fumes (Sax 1984, p. 429).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and irritating fumes (Sax 1984, p. 429).
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CAS Registry Number: 1464-53-5
Page 3 of 3
DIEPOXYBUTANE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is used as a research chemical (*SRI); in curing polymers; crosslinking
textile fibers; and to prevent microbial spoilage (Merck 1983, p. 531).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene POOR/LIMITED**
Nitrile POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include swelling of the
eyelids, upper respiratory tract irritation, and delayed eye irritation
(Encyc Occupat Health and Safety 1983, p. 772).
Emergency and First Aid Procedures: (Poisonous Liquid or Gas, n.o.s.)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Remove and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush with running water for at least 15
minutes. Keep victim quiet and maintain normal body temperature. Effects
may be delayed; keep victim under observation (DOT 1984, Guide 15).
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CAS Registry Number: 1558-25-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 9, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ TRICHLORO(CHLOROMETHYL)SILANE
CAS Registry Number: 1558-25-4
Synonyms: (SANSS 1983 Synonyms) Silane, Trichloro(Chloromethyl)-;
(Chloromethyl)Trichlorosilane; Trichloro(Chloromethyl) Silane
Chemical Formula: CH2Cl4Si
Molecular Weight: 184
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.03 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 1558-25-4
Page 2 of 3
TRICHLORO(CHLOROMETHYL)SILANE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific ~ Methyl
Trichlorosilane) If inhaled, may be harmful; contact may cause burns to
skin and eyes. Runoff from fire control or dilution water may cause
pollution (DOT 1984, Guide 29).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Methyl Trichlorosilane) Small
fires: Dry chemical, CO2, halon, water spray, or standard foam. Large
fires: Water spray, fog, or standard foam is recommended (DOT 1987, Guide
29).
Special Fire Fighting Procedures: (Non-specific -- Methyl Trichlorosilane)
Move container from fire area if you can do it without risk. Do not get
water inside container. Cool containers that are exposed to flames with
water from the side until well after fire is out. Stay away from ends of
tanks. Withdraw immediately in case of rising sound from venting safety
device or any discoloration of tank due to fire (DOT 1987, Guide 29).
Unusual Fire and Explosion Hazards: (Non-specific - Methyl Trichloro-
silane) Flammable/Combustible material; may be ignited by heat, sparks, or
flames. Vapors may travel to a source of ignition and flash back.
Container may explode in heat of fire. Vapor explosion hazard indoors,
outdoors, or in sewers. Runoff to sewer may create fire or explosion
hazard. May react violently with water (DOT 1987, Guide 29).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 1558-25-4
Page 3 of 3
TRICHLORO(CHLOROMETHYL)SILANE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Methyl Trichlorosilane) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
If water pollution occurs, notify appropriate authorities. Shut off
ignition sources; no flares, smoking or flames in hazard area. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors; do not get water inside container. Small spills:
flush area with flooding amounts of wt er. Large spills: dike far ahead
of spill for later disposal (DOT 1984, Guide 29).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1558-25-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
TRICHLORO (CHLOROMETHYL) SILANE
(1558-25-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Sharp, biting.
Commercial Form - Liquid in 1-gallon bottles (in steel containers) or 55-gallon
drums.
Use - Manufacture of silicone products.
Material to Avoid - Water (except for use in emergency life support).
Caution: Extremely flammable; may spontaneously ignite. Avoid sources of
extreme heat or ignition including sparks or fire. Trichloro (chloromethyl)
silane will liberate hydrochloric acid upon contact with water.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Trichloro (Chloromethyl) Silane Exposure:
Signs and symptoms of acute ingestion of trichloro (chloromethyl) silane may be
severe, and include increased salivation, intense thirst, difficulty
swallowing, chills, pain, and shock. Oral, esophageal, and stomach burns are
common. Vomitus generally has a coffee-ground appearance. The potential for
circulatory collapse is high following ingestion of trichloro (chloromethyl)
silane.
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EFATG
CAS Registry Number: 1558-25-4
Page 2 of 3
TRICHLORO (CHLOROMETHYL) SILANE
Acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea
(shortness of breath), respiratory tract irritation, and chest pain. Bleeding
of nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema,
chronic bronchitis, and pneumonia may also occur.
If the eyes have come in contact with trichloro (chloromethyl) silane,
irritation, pain, swelling, corneal erosion, and blindness may result.
Dermatitis (red, inflamed skin), severe burns, pain, and shock generally
follow dermal exposure.
Emergency Life-Support Procedures:
Acute exposure to trichloro (chloromethyl) silane may require decontamination
and life support for the victims. Emergency personnel should wear protective
clothing appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to trichloro (chloromethyl) silane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to trichloro (chloromethyl) silane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
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EFATG
CAS Registry Number: 1558-25-4
Page 3 of 3
TRICHLORO (CHLOROMETHYL) SILANE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Rinse mouth with large amounts of water. Instruct victims not to swallow
this water.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
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CAS Registry Number: 1563-66-2
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CARBOFURAN
CAS Registry Number: 1563-66-2
Synonyms: Carbamic Acid, Methyl-, 2,3-Dihydro-2,2-Dimethyl-7-Benzofuranyl
Ester; 2,2-Dimethyl-2,2-Dihydrobenzofuranyl-7 N-Methylcarbamate;
2,3-Dihydro-2,2-Dimethyl-7-Benzofuranol-N-Methylcarbamate;
2,3-Dihydro-2,2-Dimethylbenzofuranyl Methylcarbamate; 2,3-Dihydro-2,2-
Dimethylbenzofuranyl-7-N-Methylcarbamate; 7-Benzofuranol, 2,3-Dihydro-
2,2-Dimethyl-, Methylcarbamate; Bay 70143; Chinufur; Curaterr; D 1221; ENT
27,164; FMC 10242; Furadan; Furadan 3G; Furodan; NIA 10242; Niagara 10242;
Niagara Nia-10242; OMS 864; Yaltox; 7-Benzofuranol, 2,3-Dihydro-2,2-Dimethyl-,
Methylcarbamate
Chemical Formula: C12H15NO3
Molecular Weight: 221.28
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.043 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.18 at 20°C (*Farm Chemicals Handbook 1984)
Vapor Pressure (mmHg): 0.00002 at 33°C (*Farm Chemicals Handbook 1984)
Melting Point: 302-307°F, 150-153°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 1563-66-2
Page 2 of 3
CARBOFURAN
SECTION II (continued)
Solubility in Water: 700 ppm at 25°C (*Merck 1976)
Appearance and Odor: White crystalline solid (*Merck 1976); odorless
(*Farm Chemicals Handbook 1984)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 mg/m3 (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
poisonous. May be fatal if swallowed, inhaled, or absorbed through skin.
Contact may burn skin or eyes (*DOT 1984). Probable lethal oral dose to
humans 5 to 50 mg/kg or 7 drops to 1 teaspoon for 150 Ib. person (*Gosselin
1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray, or
foam. Dike fire control water for later disposal, do not scatter the
material (*DOT 1984).
Special Fire Fighting Procedures: Stay at maximum distance (*DOT 1984).
Unusual Fire and Explosion Hazards: May release nitrogen oxides (Sax
1984, p. 1152). Containers may explode in heat of fire (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Under neutral or acid conditions (*Spencer
1982)
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CAS Registry Number: 1563-66-2
Page 3 of 3
CARBOFURAN
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Alkalies (*Merck 1976)
Hazardous Decomposition or Byproducts: Nitrogen oxides (Sax 1984, p.
1152)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide on corn, alfalfa, tobacco and other
field crops (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
In case of releases or spills, stay upwind; keep out of low areas.
Ventilate closed spaces before entering them (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplie air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1563-66-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
CARBOFURAN
(1563-66-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White crystalline solid.
Odor - None.
Commercial Forms - 2, 3, 5 and 10% pure granules; 75% pure wettable powder;
flowable paste.
Use - Pesticide.
Other Names - Bay 70143; Brifur; carbamic acid, methyl-, 2,3-dihydro-2,2-
dimethyl-7-benzofuranyl ester; Curaterr; Furadan; Yaltox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of- Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, diazepam, phenytoin, protopam.
Signs and Symptoms of Acute Carbofuran Exposure:
Acute exposure to carbofuran usually leads to a cholinergic crisis. Signs and
symptoms may include increased salivation, lacrimation (tearing), and
spontaneous defecation and urination. Pinpoint pupils, along with blurred
vision, tremor, muscle twitching, convulsions, mental confusion, and coma may
also occur. Gastrointestinal effects include nausea, vomiting, diarrhea, and
abdominal pain.
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EFATG
CAS Registry Number: 1563-66-2
Page 2 of 3
CARBOFURAN
Bradycardia (slow heart rate) occurs frequently. Muscle coordination may be
diminished. Dyspnea (shortness of breath) may lead to respiratory collapse.
Emergency Life-Support Procedures:
Acute exposure to carbofuran may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to carbofuran.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to carbofuran.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
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EFATG
CAS Registry Number: 1563-66-2
Page 3 of 3
CARBOFURAN
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
' ingestion of carbofuran is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of carbofuran may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of
cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 1600-27-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MERCURIC ACETATE
CAS Registry Number: 1600-27-7
Synonyms: Acetic Acid, Mercury(2+) Salt; Bis(acetyloxy)Mercury;
Diacetoxymercury; Mercuriacetate; Mercuric Diacetate; Mercury (II) Acetate;
Mercury Acetate; Mercury Diacetate; Mercury(2+) Acetate; Mercuryl Acetate
Chemical Formula: Hg(C2H3O2)2
Molecular Weight: 318.70
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 23.9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes (Merck 1983, p. 839)
Specific Gravity (H2O=1): 3.270 (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 352-356°F, 178-I80°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 25 g/100 mL of water at 10°C, 100 g/100 mL of water
at 100°C (*Weast 1979)
Appearance and Odor: White scales or powder (*Weast 1979); crystals or
crystalline powder with a slight acetic odor (Merck 1983, p. 839); white
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CAS Registry Number: 1600-27-7
Page 2 of 3
MERCURIC ACETATE
SECTION II (continued)
solid with a mild vinegar-like odor (Weiss 1980, p. 579)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Mercury and inorganic compounds) Ceiling 0.1 mg/ms, as mercury
(NIOSH 1987, p. 152)
ACGIH TLV: (Aryl and inorganic compounds) TWA 0.1 mg/ms, as mercury (skin)
(ACGIH 1986-87, p. 22)
IDLH: Not Found
Other Limits Recommended: (Mercury and inorganic compounds) NIOSH:
0.05 mg/m3 10-hour TWA, as mercury (NIOSH 1987, P. 152)
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 653)
Skin: Yes (Hawley 1981, p. 653)
Ingestion: Yes (Sax 1984, p. 174)
Health Hazards (Acute, Delayed, and Chronic): It may cause death by
hypovolemic shock or kidney failure. Chronic exposure may lead to kidney
failure (*Gilman 1980, "Clayton and Clayton 1981-82).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable (Weiss 1980, p. 579). Extinguish
fire using agent suitable for type of surrounding fire. Material itself
does not burn or burns with difficulty. Use water in flooding quantities
as fog. Use foam, carbon dioxide or dry chemical to extinguish fires
(Student 1981, p. 324).
Special Fire Fighting Procedures: Avoid breathing dusts, and fumes from
burning material. Keep upwind. Avoid bodily contact with the material.
Wear boots, protective gloves, and goggles. Do not handle broken packages
without protective equipment. Wash away any material which may have
contacted the body with copious amounts of water or soap and water. Wear
self-contained breathing apparatus when fighting fires involving this
material. If contact with the material is anticipated, wear full
protective clothing (Student 1981, p. 324).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of mercury (Sax 1984, p. 1747).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 1600-27-7
Page 3 of 3
MERCURIC ACETATE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 579)
Conditions to Avoid: Light (Sax 1984, p. 1747)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of mercury (Sax 1984, p. 1747).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chiefly for mercuration of organic compounds; for the absorption of
ethylene (Merck 1983, p. 839), as a chemical intermediate for
phenylmercuric acetate, a mildewicide, and other organomercury compounds
(*SRI); catalyst in organic synthesis; and in the manufacture of
Pharmaceuticals (Hawley 1981, p. 653)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing dusts (see Section III above).
If material is not involved in fire, keep material out of water
sources and se vers (Student 1981, p. 324). Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: Dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 1600-27-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
MERCURIC ACETATE
(1600-27-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White crystals or white to yellow powder.
Odor - Mild, vinegarlike.
Commercial Forms - Crystals or powder shipped in glass, earthenware,
composition bottles or jars, metal packaging, fiber cartons, cans, and boxes.
Uses - Pesticide, manufacture of Pharmaceuticals, mercuration of organic
compounds, absorption of ethylene, catalyst.
Materials to Avoid - Reducing agents.
Caution: Avoid sources of heat including fire. Mercuric acetate will liberate
toxic mercury fumes when heated to decomposition.
Other Names - Diacetox'-mercury, mercuriacetate, mercury diacetate, mercuryl
acetate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, penicillamine, dimercaprol.
-------
EFATG
CAS Registry Number: 1600-27-7
Page 2 of 3
MERCURIC ACETATE
Signs and Symptoms of Acute Mercuric Acetate Exposure:
Warning: Effects may be delayed. Camion is advised.
Signs and symptoms of acute exposure to mercuric acetate may be severe and
include increased salivation, foul breath, inflammation and ulceration of the
mucous membranes, abdominal pain, and bloody diarrhea. Oliguria (scanty
urination), anuria (suppression of urine formation), and acute renal failure
may be noted. Weak pulse, seizures, psychic disturbances, dyspnea (shortness
of breath), chest pain, and circulatory collapse may be observed. Dermal
exposure may result in dermatitis (red inflamed skin).
Emergency Life-Support Procedures:
Acute exposure to mercuric acetate may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to mercuric acetate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to mercuric acetate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
-------
EFATG
CAS Registry Number: 1600-27-7
Page 3 of 3
MERCURIC ACETATE
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas for at least 15 minutes with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 1622-32-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ETHANESULFONYL CHLORIDE, 2-CHLORO-
CAS Registry Number: 1622-32-8
Synonyms: (SANSS 1983 Synonyms) beta-Chloroethanesulfonyl Chloride;
2-Chloroethane Sulfochloride; 2-Chloroethanesulfonic Acid Chloride;
2-Chloroethanesulfonyl Chloride; 2-Chloroethylsulfonyl Chloride
Chemical Formula: C2H4C12O2S
Molecular Weight: 163
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.25 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 392-397°F, 200-203°C (Weast 1978, p. C-295)
Specific Gravity (H2O=1): 1.55 at 20°C/4°C (Weast 1978, p. C-295)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (Weast 1978, p. C-295)
Appearance and Odor: Not Found
-------
CAS Registry Number: 1622-32-8
Page 2 of 3
ETHANESULFONYL CHLORIDE, 2-CHLORO-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 1622-32-8
Page 3 of 3
ETHANESULFONYL CHLORIDE, 2-CHLORO-
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS:
Sources searched but no information found:
NIOSH/RTECS 1983
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
Sax 1984
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 1642-54-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIETHYLCARBAMAZINE CITRATE
CAS Registry Number: 1642-54-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, page 185)
1-Piperazinecarboxamide, N,N-Diethyl-4-Methyl-, Citrate (1:1); Banocide;
Caricide; Caritrol; Cypip; Dicarocide; Diethylcarbamazine Acid Citrate;
Diethylcarbamazane Citrate; Diethylcarbamazine Hydrogen Citrate;
l-Diethylcarbamoyl-4-Methylpiperazine Dihydrogen Citrate;
N,N-Diethyl-4-Methyl-l-Piperazinecarboxamide Citrate;
N,N-DiethyI-4-Methyl-l-Piperazinecarboxamide Dihydrogen Citrate; Ditrazin;
Ditrazine; Ethodryl Citrate; Franocide; Franozan; Hetrazan; Loxuran;
1 -Piperazinecarboxamide, N,N-Diethyl-4-Methyl-, 2-Hydroxy-1,2,3-Propanetri-
carboxylate
Chemical Formula: C10H21N3O C6H8O7
Molecular Weight: 391.48
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.309 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 286-289°F, 141-143°C (Merck 1983, p. 453)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 1642-54-2
Page 2 of 4
DIETHYLCARBAMAZINE CITRATE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Merck 1983, p. 453)
Appearance and Odor: Crystalline solid (Merck 1983, p. 453); scored white
tablets (Physician's Desk Reference, 1980, p. 979)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1006)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Drugs,
n.o.s.) May be fatal if inhaled, swallowed or absorbed through skin.
Contact may cause burns to skin and eyes. Fire may produce irritating or
poisonous gases. Runoff from fire control or dilution water may cause
pollution (DOT 1984, Guide 11). The average adult man tolerates a single
dose of 1.5 gm without ill effects (Gosselin 1984, p. 11-388).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 1642-54-2
Page 3 of 4
DIETHYLCARBAMAZINE CITRATE
SECTION V (continued)
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1006)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1006).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used against filariasis in man and animals. Especially popular in
veterinary medicine (Gosselin 1984, p. 11-388).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Drugs, n.o.s.) Shut off ignition sources; no flares,
smoking or flames in hazard area. Keep combustibles (wood, paper, oil,
etc.) away from spilled material. Do not touch spilled material. Small
spills: take up with sand or other noncombustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal. Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas (DOT 1984,
Guide 11).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Untoward reactions include nausea,
vomiting, headache, weakness, and (as seen in dogs) muscle tremors and
convulsions (Gosselin 1984, p. 11-388).
Emergency and First Aid Procedures: (Non-Specific — Drugs, n.o.s.) Move
victim to fresh air; call emergency medical care. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case
of contact with material, immediately flush skin or eyes with running water
-------
CAS Registry Number: 1642-54-2
Page 4 of 4
DIETHYLCARBAMAZINE CITRATE
SECTION IX (continued)
for at least 15 minutes. Remove and isolate contaminated clothing and
shoes at the site. Keep victim quiet and maintain normal body temperature
(DOT 1984, Guide 11).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Oilman 1985
-------
CAS Registry Number: 1752-30-3
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ACETONE THIOSEMICARBAZIDE
CAS Registry Number: 1752-30-3
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 233) Acetone,
Thiosemicarbazone; Hydrazinecarbothioamide, 2-(l-Methylethylidene)-;
Thiosemicarbazone Acetone
Chemical Formula: C4H9N3S
Molecular Weight: 131.22
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 1752-30-3
Page 2 of 3
ACETONE THIOSEMICARBAZIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1985, p. 2576)
Health Hazards (Acute, Delayed, and Chronic): High oral toxicity (Sax
1984, p. 2576).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
2576).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2576)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
2576).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not found
-------
CAS Registry Number: 1752-30-3
Page 3 of 3
ACETONE THIOSEMICARBAZIDE
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Weast 1979
Merck 1983
Hawley 1981
Hayes 1982
Farm Chemicals Handbook 1984
Encyc Occupat Health and Safety 1983
Verschueren 1983
Gosselin 1984
Clayton and Clayton 1981-82
DOT 1984
Student 1981
Buchel 1983
Weiss 1980
CHRIS 1978
DOT 1984
NFPA 1984
Doull 1980
Arena 1979
-------
CAS Registry Number: 1910-42-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PARAQUAT
CAS Registry Number: 1910-42-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 719) 4,4'-Bipyridinium,
l,l'-Dimethyl-, Dichloride; Bipyridinium, l,l'-Dimethyl-4,4'-, Dichloride;
Crisquat; Dextrone-X; Dexuron; N,N'-Dimethyl-4,4'- Bipyridynium Dichloride;
N,N'-Dimethyl-4,4'-Bipyridylium Dichloride; l,r-Dimethyl-4,4'-Bipyridynium
Dichloride; 4,4'-Dimethyldipyridyl Dichloride; l,r-Dimethyl-4,4'-Dipyridylium
Chloride; N,N'-Dimethyl-4,4'-Dipyridylium Dichloride; Esgram; Gramonol;
Gramoxone; Gramoxone S; Gramuron; Methylviologen; Methyl Viologen (Reduced);
Ortho Paraquat Cl; Para-Col; Paraquat Chloride; Paraquat Cl; Paraquat,
Dichloride; Pathclear; Pillaquat; Pillarxone; Terraklene; Totacol; Toxer Total;
Viologen, Methyl-; Weedol
Chemical Formula: C12H14N2 2C1
Molecular Weight: 257.18
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(guinea pig) 22 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Approximately 0 (NIOSH/OSHA 1978, p. 146)
Melting Point: Decomposes 572°F, 300°C (Merck 1983, p. 1009)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 1910-42-5
Page 2 of 3
PARAQUAT
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble in water (ACGIH 1980, p. 319)
Appearance and Odor: Colorless to yellow crystalline solid (Farm
Chemicals Handbook 1984, p. C172; Merck 1983, p. 1009)
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: (Paraquat compounds) TWA 0.5 mg/m3 (NIOSH 1987, p. 184)
ACGIH TLV: (Respirable sizes) TWA 0.1 mg/m3 (ACGIH 1986-87, p. 26)
IDLH: 1.5 mg/m3 (NIOSH/OSHA 1978, p. 146)
Other Limits Recommended: Maximum air concentration (Bulgaria) 0.01 mg/m3
(Encyc Occupat Health and Safety 1983, p. 1037)
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 776)
Skin: Yes (Hawley 1981, p. 776)
Ingestion: Yes (Farm Chemicals Handbook 1984,
p. C172)
Health Hazards (Acute, Delayed, and Chronic): Can cause death due to
severe injury to the lungs (Sax 1984, p. 2117). The lowest lethal oral
dose reported in humans is 43 mg/kg (NIOSH/RTECS 1983, p. 719).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is a bipyridilium compound (Buchel
1983, p. 376). Procedures for bipyridilium pesticides are as follows.
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam. Move container from fire area if you
can do so without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 1910-42-5
Page 3 of 3
PARAQUAT
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
p. 146).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Contact herbicide and desiccant (Farm Chemicals Handbook 1984, p. C172).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Bipyridilium Pesticide) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. If water pollution occurs, notify
appr ,-priate authorities. Do not touch spilled material; stop leak if you
can do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFAJG
CAS Registry Number: 1910-42-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
PARAQUAT
(1910-42-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to yellow crystalline solid.
Uses - Herbicide, desiccant.
Materials to Avoid - Strong oxidizers, alkali, metals.
Other Names - l,l'-Dimethyl-4,4'-bipyridinium dichloride; methylviologen;
paraquat dichloride; Pathclear; Terraklene; Weedol.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment act Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Paraquat Exposure:
Warning: Effects occur in two stages, immediate and delayed. Caution is
advised. Exposure to paraquat may be fatal; there is no effective antidote.
Signs and symptoms of acute exposure to paraquat may be severe and include
nausea, vomiting, diarrhea, and abdominal pain. A burning sensation of the
mouth and esophagus with possible ulceration may occur following ingestion.
Eye exposure may result in corneal opacification (cloudiness). Dermatitis and
nail atrophy may occur following dermal contact.
Delayed effects include transient reversible liver injury, acute renal failure,
and progressive pulmonary fibrosis with associated dyspnea (shortness of
breath) and pulmonary edema.
-------
EFATG
CAS Registry Number: 1910-42-5
Page 2 of 3
PARAQUAT
Emergency Life-Support Procedures:
Acute exposure to paraquat may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to paraquat.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to paraquat.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 1910-42-5
Page 3 of 3
PARAQUAT
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of paraquat is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 1982-47-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLOROXURON
CAS Registry Number: 1982-47-4
Synonyms: Urea, 3-(p-(p-Chlorophenoxy)Phenyl)-l,l-Dimethyl-;
3-(p-(p-Chlorophenoxy)Phenyl)-l,l-Dimethylurea; C1983; Chloroxifenidim; CIBA
1983; N'-4-(4-Chlorophenoxy)Phenyl-N,N-Dimethylurea; Norex; Tenoran; Urea,
N'-(4-(4-Chlorophenoxy)Phenyl)-N,N-Dimethyl-
Chemical Formula: C16H15C1N2O2
Molecular Weight: 290.7
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(dog) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.34 at 20°C (Worthing 1983)
Vapor Pressure (mmHg): 0.0000000018 at 20°C (Worthing 1983, p. 121)
Melting Point: 304-306°F, 151-152°C ('Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 3.7 mg/liter at 20°C and pH 7 (*Spencer 1973)
Appearance and Odor: Colorless powder (Worthing 1983). White crystals
(*Spencer 1973). Odorless (*Weed Science Society of America 1979).
-------
CAS Registry Number: 1982-47-4
Page 2 of 3
CHLOROXURON
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 753)
Health Hazards (Acute, Delayed, and Chronic): This is highly toxic by
ingestion (Sax 1984, p. 753). Under certain conditions, chloroxuron will
form carcinogenic dimethylnitrosamine (*Egert and Greim, Food Cosmetic
Toxicology 14(3)193(1976)).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Non-flammable (*Weed Science Society of America 1979)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.) For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Avoid breathing vapors or dust. Wear self-contained (positive
pressure if available) breathing apparatus and full protective clothing
(DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Pesticide, Solid,
n.o.s.) Fire may produce irritating or poisonous gases (DOT 1984, Guide
53).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1973)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
-------
CAS Registry Number: 1982-47-4
Page 3 of 3
CHLOROXURON
SECTION V (continued)
emits very toxic fumes of chlorides and nitrogen oxides (Sax 1984, p. 753).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Selective pre- and early post-emergence herbicide in soybeans,
strawberries, various vegetable crops and ornamentals (*Spencer 1973).
Root- and foliage-absorbed herbicide selective in leek, celery, onion,
carrot and strawberry (Buchel 1983, p. 353). Herbicidal urea (Hayes 1982,
p. 540). Selective herbicide (Farm Chemicals Handbook 1984, p. C-220).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material;
stop leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other noncombustible absorbent
material and place into containers for later disposal. Small dry spills:
with clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53). Use caution with this material
(Farm Chemicals Handbook 1984, p. C-220).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Safest decontaminant is water with
soap. If any question of exposure, skin decontamination should be
thorough. Eye exposure: irrigate eyes with plain tap water (*Rumack 1975
to Present).
-------
CAS Registry Number: 2001-95-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - VALINOMYCIN
CAS Registry Number: 2001-95-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, page 905) Antibiotic N-329
B; Valinomicin
Chemical Formula: C^HgoNeOjg
Molecular Weight: 1111.50
SECTION I « REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 2.5 rag/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 374°F, 190°C (Merck 1983, p. 1417)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (Merck 1983, p. 1417)
Appearance and Odor: Shiny crystalline solid (Merck 1983, p. 1417)
-------
CAS Registry Number: 2001-95-8
Page 2 of 4
VALINOMYCIN
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2717)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally (Sax 1984, p. 2717).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, Solid, n.o.s.) Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam. Move container from fire area if you can do so
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2717).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 2001-95-8
Page 3 of 4
VALINOMYCIN
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Nitrogen oxides (Sax 1984, p.
2717)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide and nematocide (Merck 1983, p.
1417). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do so without risk. Small spills: absorb with sand or
other noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
-------
CAS Registry Number: 2001-95-8
Page 4 of 4
VALINOMYCIN
SECTION IX (continued)
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 2032-65-7
Page 1 of 4
EPA CHEMICAL. PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHIOCARB
CAS Registry Number: 2032-65-7
Synonyms: 3,5-Dimethyl-4-(Methylthio)Phenol Methylcarbamate; 3,5-Dimethyl-
4-(Methylthio)Phenyl Methylcarbamate; 3-5-Dimethyl-4-Methylmercaptophenyl-N-
Methylcarbamate; 3,5-Dimethyl-4-Methylthiophenyl N-Methyicarbamate;
3,5-Xylenol, 4-(Methylthio)-, Methylcarbamate; 4-(Methylthio)-3,5-Xylyl
Methylcarbamate; 4-Methylmercapto-3,5-Dimethylphenyl N-Methylcarbamate;
4-Methylmercapto-3,5-Xylyl Methylcarbamate; 4-Methylthio-3,5-Dimethylphenyl
Methylcarbamate; B 37344; Bay 37344; Bay 5024; Bay 9026; Bayer 37344; Carbamic
Acid, Methyl-, 3,5-Dimethyl-4-(Methylthio)Phenyl Ester; Carbamic Acid,
Methyl-,4-(ethylthio)-3,5-Xylyl Ester; OCR 736; DRAZA; ENT 25,726; H 321;
Mesurol; Methyl Carbamic Acid 4-(Methylthio)-3,5-Xylyl Ester; Metmercapturon;
OMS-93; Phenol, 3,5-Dimethyl-4-(Methylthio)-, Methylcarbamate; SD 9228
Chemical Formula: CUH16NO2S
Molecular Weight: 225.3
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 15 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.0001 (Farm Chemicals Handbook 1984,
p. CHS)
Melting Point: 243°F, 117°C ('Worthing 1979)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 2032-65-7
Page 2 of 4
METHIOCARB
SECTION II (continued)
Evaporation Rate (Butyl acetate*!): Not Found
Solubility in Water: 0.0027 g/100 g water (*Farm Chemicals Handbook
1984)
Appearance and Odor: White crystalline powder (*Spencer 1982). Mild odor
(*Farm Chemicals Handbook 1984).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1177)
Skin: Yes (Sax 1984, p. 1177)
Ingestion: Yes (Sax 1984, p. 1177)
Health Hazards (Acute, Delayed, and Chronic): As a carbamate insecticide,
this compound is a reversible cholinesterase inhibitor and acts on the
nervous system. It is classified as very toxic, and the probable oral
lethal dose for humans is 50-500 mg/kg or between 1 teaspoon and 1 ounce
for a 150 Ib. adult (Gosselin 1984, p. 11-307).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a carbamate insecticide (Encyc
Occupat Health and Safety 1983, p. 1624). Extinguish with dry chemical,
carbon dioxide, water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is a solid carbamate
insecticide (Buchel 1983, p. 129). Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site. Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
-------
CAS Registry Number: 2032-65-7
Page 3 of 4
METHIOCARB
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen and sulfur oxides (Sax 1984, p. 1177).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide and immobilizing agent for birds (*Rossoff 1974), acaricide and
molluscicide (*Worthing 1979)
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation of material (see Section III above). This compound is a
solid carbamate insecticide (Buchel 1983, p. 129). Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: With clean shovel, place material into clean, dry container and
cover; move containers from spill area. Large spills: Dike far ahead of
spill for later disposal. Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Remove and isolate contaminated clothing
at the site. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2032-65-7
Page 4 of 4
METHIOCARB
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include salivation, slowed
heartbeat, spontaneous urination and defecation, labored breathing,
headache, blurred vision, tremor, slight paralysis, and muscle twitching.
In severe poisoning, unconsciousness and convulsions may occur. Nausea,
vomiting, diarrhea, and abdominal pain may be noted (*Rumack 1975 to
Present).
Emergency and First Aid Procedures: This compound is a solid carbamate
insecticide (Buchel 1983, p. 129). Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 2074-50-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PARAQUAT METHOSULFATE
CAS Registry Number: 2074-50-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 719) 4,4'-Bipyridinium,
l,l'-Dimethyl-, bis(Methyl Sulfate); 1,1'-Dimethyl- 4,4'-Bipyridynium
Dimethylsulfate; l,l'-Dimethyl-4,4'-Dipyridinium Di(Methyl Sulfate); Gramoxone
Methyl Sulfate; Paraquat bis(Methyl Sulfate); Paraquat Dimethyl Sulfate;
Paraquat Dimethyl Sulphate; PP 910
Chemical Formula: C12H14N2-(CH3O4S)2
Molecular Weight: 408.48
SECTION I » REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral
(dog) 25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes at 347-356°F, 175-180°C (NIOSH/OSHA 1978, p.
146)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Approximately 0 (NIOSH/OSHA 1978, p. 146)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Hawley 1981, p. 776)
-------
CAS Registry Number: 2074-50-2
Page 2 of 4
PARAQUAT METHOSULFATE
SECTION II (continued)
Appearance and Odor: White crystalline solid (Farm Chemicals Handbook
1984, p. C172); yellow solid (Merck 1983, p. 1009)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Paraquat compounds) 0.5 mg/m3 (NIOSH 1987, p. 184)
ACGIH TLV: (For Paraquat) TWA 0.1 mg/ms (respirable sizes) (ACGIH 1985,
p. 26)
IDLH: (Paraquat compounds) 1.5 mg/ms (NIOSH 1987, p. 184)
Other Limits Recommended: Maximum Air Concentration (Bulgaria) 0.01 mg/m3;
TLV: 0.1 mg/m3 (respirable sizes) (Encyc Occupat Health and Safety 1983,
p. 1037)
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 776)
Skin: Yes (Hawley 1981, p. 776)
Ingestion: Yes (Sax 1984, p. 2118)
Health Hazards (Acute, Delayed, and Chronic): It can cause death by shock
and/or pulmonary damage. The fatal dose is estimated to be 6 grams of
paraquat ion. Exposure may cause renal tubular damage and liver
dysfunction (Encyc Occupat Health and Safety 1983, p. 1037).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not combustible (NIOSH/OSHA 1978, p. 146).
(Non-Specific — Pesticide, Solid, n.o.s.) Extinguish with dry chemical,
carbon dioxide, water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific - Pesticide, Solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing. Move
container from fire area if you can do so without risk (DOT 1984, Guide
53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of sulfur oxides and nitrogen oxides (Sax 1984, p.
2118).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2074-50-2
Page 3 of 4
PARAQUAT METHOSULFATE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
p. 146)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of sulfur oxides and nitrogen oxides (Sax 1984, p.
2118).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Contact herbicide and desiccant (Farm Chemicals Handbook 1984, p. C172).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do so without
risk. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Small dry spills: with clean shovel place material into clean, dry
container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Death may occur in 24 hours or less.
Contact causes irritation. Inhalation causes nose bleeds, headaches,
coughing, and a sore throat. Swallowing causes burning in mouth, throat,
and abdomen, vomiting, bloody vomitus, diarrhea with bloody stools, and
headaches (NIOSH/OSHA 1978, p. 146; Hayes 1982, p. 552; Encyc Occupat
Health and Safety 1983, p. 1037; Gosseiin 1984, p. III-333).
-------
CAS Registry Number: 2074-50-2
Page 4 of 4
PARAQUAT METHOSULFATE
SECTION IX (continued)
Emergency and First Aid Procedures: (Non-Specif ic — Pesticide, Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Remove and isolate contaminated clothing and
shoes at the site (DOT 1984, Guide 53).
-------
CAS Registry Number: 2097-19-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHENYLSILATRANE
CAS Registry Number: 2097-19-0
Synonyms: 2,8,9-Trioxa-5-Aza-l-Silabicyclo[3.3.3] Undecane, Phenyl-;
Silatrane, Phenyl-
Chemical Formula: C12H17NO3Si
Molecular Weight: 251.39
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDIow oral
(rat) 1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 2097-19-0
Page 2 of 3
PHENYLSILATRANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2203)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic following
ingestion by mouth (Sax 1984, p. 2203). .
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
«
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Decomposes to toxic fumes of nitrogen
oxides when heated (Sax 1984, p. 2203).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 2203).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Toxic fumes of nitrogen oxides
when heated to decomposition (Sax 1984, p. 2203).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 2097-19-0
Page 3 of 3
PHENYLSILATRANE
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Clayton and Clayton 1981-82
Merck 1983
Verschueren 1983
Weast 1979
Student 1981
Hawley 1981
DOT 1984
-------
CAS Registry Number: 2104-64-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - EPN
CAS Registry Number: 2104-64-5
Synonyms: Phosphonothioic Acid, Phenyl-, O-Ethyl O-(p-Nitrophenyl)Ester;
Benzenephosphonic Acid, Thiono-, Ethyl-p-Nitrophenyl Ester;
Benzenephosphothionic Acid, Ethyl 4-Nitro-Phenyl Ester; ENT 17,798; EPN 300;
Ethoxy-4-Nitrophenoxyphenylphosphine Sulfide; Ethyl p-Nitrophenyl
Benzenethionophosphonate; Ethyl p-Nitrophenyl Benzenethiophosphate; Ethyl
p-Nitrophenyl Benzenethiophosphonate; Ethyl p-Nitrophenyl
Phenylphosphonothioate; Ethyl p-Nitrophenyl Thionobenzenephosphate; Ethyl
p-Nitrophenyl Thionobenzenephosphonate; O-Ethyl O-(4-Nitrophenyl)
Benzenethionophosphonate; O-Ethyl O-(4-Nitrophenyl) Phenylphosphonothioate;
O-Ethyl O-(p-Nitrophenyl) Phenylphosphonothioate; O-Ethyl O-p-Nitrophenyl
Benzenethiophosphonate; O-Ethyl O-p-Nitrophenyl Phenylphosphonothiolate;
O-Ethyl O-p-Nitrophenyl Phenylphosphorothioate; O-Ethyl Phenyl p-Nitrophenyl
Thiophosphonate; Phenol, p-Nitro-, O-Ester with O-Ethyl Phenyl
Phosphonothioate; Phenylphosphonothioate, O-Ethyl-O-p-Nitrophenyl-;
Phosphonothioic Acid, Phenyl-, O-Ethyl O-(4-Nitrophenyl) Ester; PIN; Santox
Chemical Formula: C14H14NO4PS
Molecular Weight: 323.30
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral
(rat) 8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.268 at 77°F, 25°C (*Merck 1976)
Vapor Pressure (mmHg): 0.0003 at 212°F, 100°C (*Worthing 1979)
-------
CAS Registry Number: 2104-64-5
Page 2 of 4
EPN
SECTION II (continued)
Melting Point: 97°F, 36°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Merck 1976)
Appearance and Odor: Light yellow crystalline powder ('Worthing 1979);
aromatic odor (*Merck 1976).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.5 mg/m3 (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.5 mg/ms (skin) (ACGIH 1986-87, p. 18)
IDLH: 50 mg/m8 (NIOSH/OSHA 1978, p. 94)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Farm Chemicals Handbook 1983)
Skin: Yes (*Farm Chemicals Handbook 1983)
Ingestion: Yes (*Farm Chemicals Handbook 1983)
Health Hazards (Acute, Delayed, and Chronic): This material may be fatal
if swallowed. It is poisonous if inhaled and extremely hazardous by skin
contact. Repeated exposure may, without symptoms, be increasingly
hazardous (*Farm Chemicals Handbook 1983). The estimated fatal oral dose
is 0.3 grams for a 150 Ib. (70 kg) person (*Arena 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Organophosphorus Pesticide,
n.o.s.) For small fires, use dry chemical, carbon dioxide, water spray, or
foam. For large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 2104-64-5
Page 3 of 4
EPN
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) This material may burn but does not ignite readily.
Container may explode in heat of fire. Fire and runoff from fire control
water may produce irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*ACGIH 1980)
Conditions to Avoid: Hydrolyzed by alkali (*Worthing 1979)
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
P. 94)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an insecticide for cotton (*SRI) and an acaricide
(*Worthing 1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill. Cover with soda ash, mix, and spray with water.
Place in container of water and allow to stand for 2 days, then neutralize
with 6 molar hydrochloric acid (*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2104-64-5
Page 4 of 4
EPN
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 2104-64-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
EPN
(2104-64-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Light yellow, crystalline powder.
Odor - Aromatic.
Commercial Forms - Dark amber-colored liquid, wettable powders and dusts.
Use - Pesticide.
Materials to Avoid - Strong oxidizers, alkali.
Other Names - Ethyl p-nitrophenyl benzenethiophosphate, PIN, Santox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute EPN Exposure:
Warning: Extremely hazardous by skin contact. Effects may be delayed up to 12
hours. Caution is advised.
Acute exposure to EPN may produce the following signs and symptoms: pinpoint
pupils, blurred vision, headache, dizziness, muscle spasms, and profound
weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may also
occur.
-------
EFATG
CAS Registry Number: 2104-64-5
Page 2 of 3
EPN
The heart rate may decrease following oral exposure or increase following
dermal exposure. Hypertension (high-blood pressure) is not uncommon.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression and respiratory paralysis. Giddiness, slurred speech, confusion,
and psychosis may also be observed.
Emergency Life-Support Procedures:
Acute exposure to EPN may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to EPN.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to EPN.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
-------
EFATG
CAS Registry Number: 2104-64-5
Page 3 of 3
EPN
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of EPN is unknown or suspected to be greater than 30 minutes,
do not induce vomiting and proceed to Step 4. Ipecac should not be
administered to children under 6 months of age.
Warning: Ingestion of EPN may result in sudden onset of seizures or loss
of consciousness. Syrup of Ipecac should be administered only if victims
are alert, have an active gag-reflex, and show no signs of impending
seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 2223-93-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CADMIUM STEARATE
CAS Registry Number: 2223-93-0
Synonyms: Octadecanoic Acid, Cadmium Salt; Alaixol 11; Cadmium Distearate;
Cadmium Octadecanoate; SCD; Stabilisator SCO; Stabilizer SCO; Stearic Acid,
Cadmium Salt
Chemical Formula: CS6H72O4Cd
Molecular Weight: 681.48
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
»
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.13 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Cadmium Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR»1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 2223-93-0
Page 2 of 3
CADMIUM STEARATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: (Cadmium dusts and salts) TWA 0.05 mg/ms, as cadmium (ACGIH
1986-87, p. 11)
IDLH: Not Found
Other Limits Recommended: IDLH for cadmium dust 40 mg/ms (NIOSH/OSHA 1971
P. 58)
Routes of Entry: Inhalation: Yes (Similar to cadmium) (*Rumack 1975
to Present)
Skin: Not Found
Ingestion: Yes (Similar to cadmium) (*Rumack 1975
to Present)
Health Hazards (Acute, Delayed, and Chronic): Similar to cadmium; acute
tpxicity most notably occurs secondary to cadmium ingestion or inhalation
of cadmium fumes. Poisoning from inhalation is relatively rare but
dangerous, having a mortality rate of about 15 percent (*Rumack 1975 to
Present). Toxic inhaled concentrations in humans have been reported at 147
mg/ms/35 minutes and at 1800 mg/ms/2 years (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Cadmium Compound) For small
fires, use dry chemicals, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific - Cadmium Compound)
Keep upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: It emits acrid smoke when heated to
decomposition (Sax 1984, p. 2079).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2223-93-0
Page 3 of 3
CADMIUM STEARATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke (Sax 1984, p. 2079).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Lubricant and stabilizer for polyvinyl chloride (*SRI). Lubricant and
stabilizer in plastics (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Cadmium Compounds) Do not touch spilled material.
Stay upwind; keep out of low areas. Take up small spills with sand
or other noncombustible absorbent material and place into containers
for later disposal. Take up small, dry spills with clean shovel
and place into clean, dry container. Dike far ahead of large spills for
later disposal (DOT 1984, Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
• demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 2223-93-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
CADMIUM STEARATE
(2223-93-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White powder.
Odor - Fatty acidlike.
Commercial Form - Powder in drums.
Uses - Lubricant, stabilizer for plastics.
Other Names - Alaixol 11; cadmium octadecanoate; Stabilizer SCD; stearic
acid, cadmium salt.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
EDTA.
Signs and Symptoms of Acute Cadmium Stearate Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
The following signs and symptoms may be noted following exposure to cadmium
stearate: cough, dyspnea (shortness of breath), either dry mouth or increased
salivation, abdominal pain, nausea, vomiting, bronchitis, and chest pain.
Vertigo (dizziness), fever, and profuse sweating may also occur.
-------
EFATG
CAS Registry Number: 2223-93-0
Page 2 of 3
CADMIUM STEARATE
Emergency Life-Support Procedures:
Acute exposure to cadmium stearate may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to cadmium stearate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or' performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to cadmium stearate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 2223-93-0
Page 3 of 3
CADMIUM STEARATE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedure^, ,.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of cadmium stearate is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 2231-57-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THIOCARBAZIDE
CAS Registry Number: 2231-57-4
Synonyms: l,3-Diamino-2-Thiourea; Carbohydrazide, Thio-; Carbonothioic
Dihydrazide; Hydrazinecarbohydrazonothioic Acid; TCH; Thiocarbohydrazide;
Thiocarbonic Dihydrazide; Thiocarbonohydrazide; USAF EK-7372
Chemical Formula: CH6N4S
Molecular Weight: 106.17
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 338°F, I70°C -- decomposes (Weast 1979, p. C-239)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Weast 1984, p. C-219)
Appearance and Odor: Crystalline needles and plates (Weast 1979, p.
C-239)
-------
CAS Registry Number: 2231-57-4
Page 2 of 3
THIOCARBAZIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2568)
Health Hazards (Acute, Delayed, and Chronic): High oral toxicity (Sax
1984, p. 2568)
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Poisonous Solid, n.o.s.)
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Wear self-contained (positive pressure if available) breathing
apparatus and full protective clothing. Stay upwind, keep out of low
areas. Move container from fire area if you can do so without risk (DOT
1984, Guide 53).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
2568).
-------
CAS Registry Number: 2231-57-4
Page 3 of 3
THIOCARBAZIDE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found -
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Has been tested as a fungicide and pesticide (*Peer Review Committee). It
is used in electron microscopy to produce electron-opaque deposits for
ultrastructural analysis (*Hoch H.C.; Planta 147(3) 1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poisonous Solid, n.o.s.) Do not touch spilled material.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel, place material into clean, dry container and cover. Move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Treat as for general poisoning.
Establish respiration. Prevent absorption. Decontaminate exposed skin
with water and soap. For eye exposure, flush thoroughly with water
(*Rumack 1975 to Present). (Non-Specific - Poisonous Solid, n.o.s.) Move
victim to fresh air; call emergency medical care. Remove and isolate
contaminated clothing and shoes at the site. In case of contact with the
material, immediately flush skin or eyes with running water for at least 15
minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 2238-07-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIGLYCIDYL ETHER
CAS Registry Number: 2238-07-5
Synonyms: bis(2,3-Epoxypropyl) Ether; DGE; Di(2,3-Epoxy)Propyl Ether; Ether,
bis(2,3-Epoxypropyl); Glycidyl Ether; NSC 54739; Oxirane,
2,2'-(Oxybis(Methylene))bis-
Chemical Formula: C6H10OS
Molecular Weight: 130.16
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.16 mg/liter/4 hours (*NIOSH/RTEC 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 500°F, 260°C (*Patty 1963)
Specific Gravity (H2O=1): 1.262 at 25°C/4°C (*Patty 1963)
Vapor Pressure (mmHg): 0.09 at 25°C (*Patty 1963)
Melting Point: Not Found
Vapor Density (AIR=1): 3.78 at 25°C (*Patty 1963) (SUSPECT)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless liquid with a pronounced irritant odor
(•Patty 1963).
-------
CAS Registry Number: 2238-07-5
Page 2 of 4
DIGLYCIDYL ETHER
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 0.5 ppm (2.8 mg/ms) (NIOSH 1987, p. 104)
ACGIH TLV: 0.1 ppm (0.5 mg/ms) (ACGIH 1983, p. 18)
IDLH: 85 ppm (NIOSH/OSHA 1978, p. 86)
Other Limits Recommended: NIOSH: 0.1 mg/m3 15-minute ceiling (NIOSH 1987,
p. 104). NIOSH occupational carcinogen (NIOSH 1987, p. 104)
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Sax 1979)
Health Hazards (Acute, Delayed, and Chronic): This compound can cause
death or permanent injury via oral and inhalation routes during exposure
that comes from normal use. It is incapacitating and poisonous and
requires special handling. It can cause considerable discomfort by the
dermal route (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 147.2°F, 64.0°C (Encyc Occupat Health and
Safety 1983, p. 787)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Poison, Flammable Liquid, n.o.s.)
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam (DOT 1984, Guide 57).
Special Fire Fighting Procedures: (Non-Specific - Poison, Flammable
Liquid, n.o.s.) Move container from fire area if you can do so without
risk. Cool containers that are exposed to flames with water from the side
until well after fire is out. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Wear
positive pressure breathing apparatus and special protective clothing (DOT
1984, Guide 57).
Unusual Fire and Explosion Hazards: (Non-Specific - Poison, Flammable
Liquid, n.o.s.) May be ignited by heat, sparks, or flames. Container may
explode in heat of fire. Vapor explosion and poison hazard indoors,
outdoors or in sewers (DOT 1984, Guide 57).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2238-07-5
Page 3 of 4
DIGLYCIDYL ETHER
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
p. 86).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a reactive diluent for epoxy resins; chemical intermediate;
stabilizer of chlorinated organic compounds; a textile-treating agent
(*Patty 1963).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Poison, Flammable Liquid, n.o.s.) Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Wear positive
pressure breathing apparatus and special protective clothing. Shut off
ignition sources; no flares, smoking, or flames in hazard area. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 57).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2238-07-5
Page 4 of 4
DIGLYCIDYL ETHER
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Irritation of the eyes and respiratory
tract, skin damage, and skin burns (ACGIH 1980, p. 143; *Patty 1963).
Emergency and First Aid Procedures: (Non-Specific — Poison, Flammable
Liquid, n.o.s.) Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least IS minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 57).
-------
CAS Registry Number: 2275-18-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PROTHOATE
CAS Registry Number: 2275-18-5
Synonyms: Phosphorodithioic Acid, O,O-DiethyI Ester, S-Ester with
N-Isopropyl-2-Mercaptoacetamide; Trimethoate; AC 18682; Acetamide,
N-Isopropyl-2-Mercapto-, S-Ester with O,O-Diethyl Phosphorodithioate; American
Cyanamid 18,682; El 18682; ENT 24,652; FAC; FAC 20; FAK-40; Fostion; Isopropyl
Diethyldithiophosphorylacetamide; L 343; N-Monoisopropylamide of
O,O-Diethyldithiophosphorylacetic Acid; O,O-Diethyl Phosphorodithioate S-Ester
with N-Isopropyl-2-Mercaptoacetamide; O,O-Diethyl S-(N-Isopropylcarbamoyl-
methyl) Dithiophosphate; O,O-Diethyl S-(N-Isopropylcarbamoylmethyl)
Phosphorodithioate; O,O-Diethyl S-Isopropylcarbamoylmethyl Phosphorodithioate;
O,O-Diethyldithiophosphorylacetic Acid, N-Monoisopropylamide; Oleofac;
Phosphorodithioic Acid, O,O-Diethyl Ester, S-Ester with N-Isopropyl-2-
Mercaptoacetamide; Phosphorodithioic Acid, O,O-Diethyl S-(2-((l-Methylethyl)
Amino)-2-Oxoethyl) Ester; Prothoat; Telefos
Chemical Formula: C9H20NOSPS2
Molecular Weight: 285.40
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCgo inhalation
(rat) 0.165 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.151 at 32°C ('Worthing 1979)
Vapor Pressure (mmHg): 0.0001 at 40°C ('Worthing 1979)
Melting Point: 83.3°F, 28.5°C; technical product solidifies at 70-75°F,
21-24°C ('Worthing 1979).
-------
CAS Registry Number: 2275-18-5
Page 2 of 4
PROTHOATE
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 2.5 g/liter at 68°F, 20°C (*Worthing 1979)
Appearance and Odor: Colorless crystalline solid, camphor-like odor.
Technical product is amber to yellow semi-solid (*Worthing 1979).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Organophosphorus
Pesticide, n.o.s.) (DOT 1984, Guide 55)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Sax 1979)
Health Hazards (Acute, Delayed, and Chronic): This is a highly toxic
material capable of causing death or permanent injury due to exposures
during normal use. Small doses at frequent intervals are additive.
Similar to parathion (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 2275-18-5
Page 3 of 4
PROTHOATE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire. Fire and.runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1982)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is an insecticide (*SRI) and an acaricide (*Worthing 1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2275-18-5
Page 4 of 4
PROTHOATE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
'Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms may include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
dizziness, weakness, muscle twitching, difficult breathing, blurring or
dimness of vision, and loss of muscle coordination. Death may occur from
failure of the respiratory center, paralysis of the respiratory muscles,
intense bronchoconstriction, or all three (*Gosselin 1976).
»*-
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticides, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55). If material has been ingested,
induce vomiting with ipecac (*Morgan 1982).
-------
CAS Registry Number: 2497-07-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - OXYDISULFOTON
CAS Registry Number: 2497-07-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 141) Phosphorodithioic
Acid, O,O-Diethyl S-((Ethylsulfinyl)Ethyl)Ester; O,O-Diethyl
S-(2-Ethylsulfinyl)Ethyl Phosphorodithioate; Disyston S; Oxydemeton-Ethyl;
Phosphorodithioic Acid, O,O-Diethyl S-[2-(Ethylsulfinyl) Ethyl) Ester; BAY
23323; DEPD; Disyston Sulfoxide; Disyston Sulphoxide; Ethylthiometon Sulfoxide
Chemical Formula: C8H19O3PS3
Molecular Weight: 290.42
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 12 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 2497-07-6
Page 2 of 4
OXYDISULFOTON
SECTION II (continued)
Solubility in Water: Not Found
Appearance and Odor: Not Found
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 2108)
Ingestion: Yes (Sax 1984, p. 2108)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally and through the skin (Sax 1984, p. 2108). This material is an
organophosphate pesticide (Buchel, 1983, p. 178).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Fight fire from maximum distance. Dike fire control
water for later disposal; do not scatter the material. Poisonous gases may
be generated from the fire or runoff water (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Some materials may burn but none of them ignite easily.
Container may explode in the heat of fire (DOT 1984, Guide 55). When
heated to decomposition, it emits very toxic fumes of oxides of sulfur and
phosphorus (Sax 1984, p. 2108).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2497-07-6
Page 3 of 4
OXYBISULFOTON
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of oxides of sulfur and phosphorus (Sax 1984, p.
2108)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Agricultural insecticide (Buchel 1983, p. 178).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Do not touch spilled
material. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 2497-07-6
Page 4 of 4
OXYDISULFOTON
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Mild: headache, loss of appetite, nausea, dizziness.
Moderate: abdominal cramps, diarrhea, salivation, excessive tearing,
muscular cramps. Severe: fever, blue lips, lack of sphincter control,
coma, heart shock, difficult breathing (ITII 1976, p. 205).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing give artificial respiration. If breathing is difficult
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 2524-03-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ DIMETHYL PHOSPHOROCHLORIDOTHIOATE
CAS Registry Number: 2524-03-0
Synonyms: Chlorodimethoxyphosphine Sulfide; Dimethoxy Thiophosphonyl
Chloride; Dimethyl Chlorothionophosphate; Dimethyl Chlorothiophosphate;
Dimethyl Thionophosphorochloridate; Dimethyl Thiophosphorochloridate; Methyl
PCT; O,O-Dimethyl Chlorothionophosphate; O,O-Dimethyl Chlorothiophosphate;
O,O-Dimethyl Phosphorochlorothioate; O,O-Dimethyl Phosphorothionochloridate;
O,O-Dimethyl Thionophosphorochloridate; O,O-Dimethyl Thiophosphoric Acid
Chloride; O,O-Dimethylphosphorochloridothioate; O,O-Dimethylthionophosphoryl
Chloride; Phosphonothioic Acid, Chloro-, O,O-Dimethyl Ester;
Phosphorochloridothioic Acid, O,O-Dimethyl Ester
Chemical Formula: C2H6C1O2PS
Molecular Weight: 160.56
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 inhalation
(mouse) 0.32 mg/liter/2 hours (*NIOSH/RTECS 1985)
TP'Q: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under, SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 151-153°F, 66-67°C at 16 mmHg (*Hawley 1977)
Specific Gravity (H2O=1): 1.320 at 25°C (*Hawley 1977)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 2524-03-0
Page 2 of 3
DIMETHYL PHOSPHOROCHLORJDOTHIOATE
SECTION II (continued)
Solubility in Water: Insoluble (*Hawley 1977)
Appearance and Odor: Colorless to light amber liquid (*Hawley 1977).
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This material is a strong
irritant to the eyes, skin, and mucous membranes (*Hawley 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found.
UEL: Not Found
Extinguishing Methods: May react violently with water. Extinguish with
dry chemical, carbon dioxide, water spray, fog, or foam (DOT 1984, Guide
59).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Move container from fire area
if you can do so without risk. Cool containers that are exposed to flames
with water from the side until well after fire is out (DOT 1984, Guide 59).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. This material may ignite combustibles (wood, paper, oil,
etc.) (DOT 1984, Guide 59).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 2524-03-0
Page 3 of 3
DIMETHYL PHOSPHOROCHLORIDOTHIOATE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated it emits very toxic
fumes of chlorine containing compounds, phosphorus oxides, and sulfur
oxides (Sax 1984, p. 1193).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a chemical intermediate for insecticides,
pesticides, and fungicides; oil and gasoline additives; plasticizers;
corrosion inhibitors; flame retardants; and flotation agents (*Hawley
1977). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). Apply powdered limestone,
slaked lime, soda ash, or sodium bicarbonate (*CHRIS 1978). Do not
touch spilled material; stop leak if you can do so without risk. Use
water spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike spill for later disposal (DOT 1984,
Guide 59).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 2524-03-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIMETHYL PHOSPHOROCHLORIDOTHIOATE
(2524-03-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to light amber liquid.
Use - Chemical intermediate for pesticides, flame retardants, other substances.
Material to Avoid - Water (except for use in emergency life support).
Caution: Avoid sources of heat including fire. Dimethyl phosphor ochlorido-
thioate will liberate toxic pkgyphorus and sulfur oxides when heated to
decomposition.
Other Names - Chlorodimethoxyphosphine sulfide, dimethoxy thiophosphonyl
chloride, dimethyl chlorothiophosphate, Methyl PCT.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate, atropine,
pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Dimethyl Phosphorochloridothioate (Methyl PCT)
Exposure:
Warning: Methyl PCT is extremely corrosive. Caution is advised.
Note: Methyl PCT is a cholinesterase inhibitor.
Acute exposure to Methyl PCT may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
-------
EFATG
CAS Registry Number: 2524-03-0
Page 2 of 3
DIMETHYL PHOSPHOROCHLORIDOTHIOATE (METHYL PCT)
The heart rate may either decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) may occur,
although hypertension (high blood pressure) is not uncommon. Chest pain may be
noted. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
Contact with the skin, eyes, or mucous membranes may result in severe
irritation, burns, and pain.
Emergency Life-Support Procedures:
Acute exposure to Methyl PCT may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to Methyl PCT.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to Methyl PCT.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
-------
EFATG
CAS Registry Number: 2524-03-0
Page 3 of 3
DIMETHYL PHOSPHOROCHLORIDOTHIOATE (METHYL PCT)
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 2540-82-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FORMOTHION
CAS Registry Number: 2540-82-1
Synonyms: Aflix; Anthio; Anthio 25; Antio; CP 53926; ENT 27,257; Formithion;
J-38; N-Formyl-N-Methylcarbamoylmethyl O,O-Dimethyl Phosphorodi- thioate;
O,O-Dimethyl Dithiophosphorylacetic Acid N-Methyl-N-Formylamide; O,O-Dimethyl
Phosphorodithioate N-Formyl-2-Mercapto-N-Methylacetamide S-Ester; O,O-Dimethyl
S-(N-Formyl-N-Methylcarbamoylmethyl) Phosphorodithioate; O,O-Dimethyl
S-(N-Methyl-N-Formylcarbamoylmethyl) Phosphorodithioate; OMS-968; P 1;
Phosphorodithioic Acid, O,O-Dimethyl Ester, N-Formyl-2-Mercapto-N-Methyl-
acetamide S-Ester; Phosphorodithioic Acid, O,O-Dimethyl Ester, S-Ester with
N-Formyl-2-Mercapto-N-Methylacetamide; Phosphorodithioic Acid,
S-(2-(Formylmethylamino)-2-Oxoethyl) O,O-Dimethyl Ester; S 6900;
S-(2-(Formylmethylamino)-2-Oxoethyl) O,O-Dimethyl Phosphorodithioate;
S-(N-Formyl-N-Methylcarbamoylmethyl) Dimethyl Phosphorothiolothionate;
S-(N-Formyl-N-Methylcarbamoylmethyl) O,O-Dimethyl Phosphorodithioate;
SAN 244 I; SAN 6913 I; SAN 7107 I; Toprose; VEL 4284
Chemical Formula: C6H12NO4PS2
Molecular Weight: 257.29
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.027 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.361 at 20°C (*Spencer 1973)
Vapor Pressure (mmHg): 0.0000085 at 20°C (*Spencer 1973)
-------
CAS Registry Number: 2540-82-1
Page 2 of 4
FORMOTHION
SECTION II (continued)
Melting Point: 77°F, 25°C (*Spencer 1973)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (*Merck 1976)
Appearance and Odor: Viscous yellow oil or crystalline mass (*Spencer
1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 1157)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Formothion is one of the
least toxic systemic organophosphates (*Agrochem Dept. of Info. Service
1971). Formothion is a compound of low to moderate toxicity (Hayes 1982,
p. 369). It causes the depression of cholinesterase (Hayes 1982, p. 370)
leading to accumulation of acetylcholine in the nervous system, which is
believed to be responsible for the symptoms (Doull 1980, p. 367).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is an organophosphorus insecticide
(Buchel 1983, p. 71). Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam. Move container
from fire area if you can do so without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter
material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is an organophosphorus
insecticide (Buchel 1983, p. 71). Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
-------
CAS Registry Number: 2540-82-1
Page 3 of 4
FORMOTHION
SECTION IV (continued)
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur
oxides (Sax 1984, p. 1157). This compound is an organophosphorus
insecticide (Buchel 1983, p. 71). Some of these materials may burn but
none of them ignite readily. Container may explode in heat of fire. Fire
and runoff from fire control water may produce irritating or poisonous
gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
%
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Martin 1974)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Alkaline pesticides; hydrolyzed by
water especially under alkaline conditions (Farm Chemicals Handbook 1984,
p. C106))
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
An insecticide and acaricide on crops and ornamentals. It is not presently
produced commercially in the U.S. (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is an organophosphorus insecticide (Buchel 1983, p. 71).
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Do not touch spilled material; stop leak if you can
do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel, place
material into clean, dry containers and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 55).
-------
CAS Registry Number: 2540-82-1
Page 4 of 4
FORMOTHION
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines', 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Early symptoms of poisoning include:
headache, dizziness, weakness, perspiring, nausea, vomiting, and sensation
of tightness in chest (*Agrochem Dept. of Info. Service 1971). Chronic low
doses may produce symptoms similar to influenza. Acute exposure causes
psychotic behavior, uncoordination, unconsciousness, convulsions, abdominal
pain, diarrhea, labored breathing, blurred vision, and profound weakness
(*Rumack 1975 to Present).
Emergency and First Aid Procedures: This compound is an organophosphorus
insecticide (Buchel 1983, p. 71). Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 2570-26-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PENTADECYLAMINE
CAS Registry Number: 2570-26-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 12) 1-Pentadecanamine;
n-Pentadecylamine; 1 -Pentadecylamine
Chemical Formula: C16HMN
Molecular Weight: 227.49
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mammal) 0.2 MR/liter (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 585.7°F, 307.6°C (Weast 1983, p. C-414)
Specific Gravity (H2O=1): 0.8104 at 20°C/4°C (Weast 1983, p. C-414)
Vapor Pressure (mmHg): Not Found
Melting Point: 99.1°F, 37.3°C (Weast 1983, p. C-414)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Flakes (Weast 1983, p. C-414)
-------
CAS Registry Number: 2570-26-5
Page 2 of 4
PENTADECYLAMINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2128)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2128)
Health Hazards (Acute, Delayed, and Chronic): This material is moderately
toxic by oral ingestion and highly toxic by inhalation (Sax 1984, p. 2128).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Alkylamine, n.o.s.) Flammable/
combustible material; may be ignited by heat, sparks, or flames. Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 29).
Special Fire Fighting Procedures: (Non-Specific — Alkylamine, n.o.s.)
Move container from fire area if you can do it without risk. Do not get
water inside container. Cool containers that are exposed to flames with
water from the side until well after fire is out. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire. Keep unnecessary people away; isolate hazard area and
deny entry. Stay upwind; keep out of low areas. Wear self-contained
(positive pressure if available) breathing apparatus and full protective
clothing. Isolate for 1/2 mile in all directions if tank car or truck is
involved in fire (DOT 1984, Guide 29).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 2128). (Non-Specific --
Alkylamine, n.o.s.) Vapors may travel to a source of ignition and flash
back. Container may explode in heat of fire. Vapor explosion hazard
indoors, outdoors or in sewers. Runoff to sewer may create fire or
explosion hazard (DOT 1984, Guide 29).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2570-26-5
Page 3 of 4
PENTADECYLAMINE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of oxides of nitrogen (Sax 1984, p. 2128).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Alkylamine, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Shut off ignition sources; no flares, smoking or flames in hazard
area. Do not touch spilled material; stop leak if you can do it
without risk. Use water spray to reduce vapors; do not get water
inside container. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 29).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Nitrile GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 2570-26-5
Page 4 of 4
PENTADECYLAMINE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Alkylamine, n.o.s.)
Move victim to fresh air; call emergency medical care. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Remove and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Keep victim quiet and maintain normal body
temperature (DOT 1984, Guide 29).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 2587-90-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: June 22, 1987
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHOSPHOROTHIOIC ACID, O.O-DIMETHYL
S-(2-(METHYLTHIO) ETHYL) ESTER
CAS Registry Number: 2587-90-8
Synonyms: Cebetox; Cymetox; Demephion; Demephion-S; Ethanethiol,
2-(Methylthio)-, O,O-Dimethyl Phosphorothioate; Ethanethiol, 2-(Methylthio)-,
S-Ester with O,O-Dimethyl Phosphorothioate; Isonitox; Methyl Demeton Methyl;
2-Methylthioethyl O,O-Dimethyl Phosphorothioate; Tinox
Chemical Formula: C6H13O3PS2
Molecular Weight: 216.27
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
20 mg/kg (*NIOSH/RTECS 1987)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 149°F, 65°C at 0.1 mmHg (decomposes) (Worthing 1979, p. 153)
Specific Gravity (H2O=1): 1.218 at 25°C/4°C (Worthing 1979, p. 153)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 300 mg/liter ('Worthing 1979, p. 153)
Appearance and Odor: Straw-colored liquid (Worthing 1979, p. 153)
-------
CAS Registry Number: 2587-90-8
Page 2 of 4
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL S-(2-(METHYLTHIO) ETHYL) ES'
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: (Non-specific — Organophosphorus
pesticide, liquid) Yes (DOT 1984,
Guide 55).
Skin: (Non-specific - Organophosphorus pesticide,
liquid) Yes (DOT 1984, Guide 55).
Ingestion: (Non-specific — Organophosphorus
pesticide, liquid) Yes (DOT 1984,
Guide 55).
Health Hazards (Acute, Delayed, and Chronic): (Non-specific —
Organophosphorus pesticide, liquid) May be fatal if inhaled, swallowed or
absorbed through the skin. Contact may cause burns to skin and eyes (DOT
1984, Guide 55). • (Non-specific — Organophosphate insecticide) May cause
respiratory fa -are (Casarett and Doull 1980, p. 367).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Organophosphorus pesticide,
liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog, or foam. Move container from
fire area if you can do so without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
pesticide, liquid, n.o.s.) Keep unnecessary people away; isolate hazard
area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate
contaminated clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
pesticide, liquid, n.o.s.) This material may burn but does not ignite
readily. Container may explode in heat of fire. Fire may produce
irritating or poisonous gases. Runoff from fire control water may give
-------
CAS Registry Number: 2587-90-8
Page 3 of 4
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL S-(2-(METHYLTHIO) ETHYL) ESTER
SECTION IV (continued)
off poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI.-- USE INFORMATION
This chemical is a systemic insecticide and acaricide effective against
sucking insects (Worthing 1979, p. 153).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus pesticide, liquid) Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small
dry spills: with clean shovel place material into clean, dry container
and cover; move containers from spill area. Large spills: dike far ahead
of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-specific -- Organophosphorus
insecticide) Exposure may cause tightness of chest, wheezing, increased
-------
CAS Registry Number: 2587-90-8
Page 4 of 4
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL S-(2-(METHYLTHIO) ETHYL) ESTEI
SECTION IX (continued)
salivation and lacrimation, increased sweating, nausea, abdominal cramps,
diarrhea, involuntary defecation, decreased heart action that can lead to
heart block, frequent and involuntary urination, constriction of the
pupils (miosis), easy fatigue, mild weakness, pallor, elevated blood
pressure, hyperglycemia (Casarett and Doull 1980, p. 367).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
pesticide, liquid) Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Merck 1983
Sax 1984
Hayes 1982
Verschueren 1983
Clayton and Clayton 1981-1982
Weiss 1980
Goodman and Oilman 1985
Weast 1986-1987
Gosselin 1984
Hawley 1981
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CAS Registry Number: 2631-37-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PROMECARB
CAS Registry Number: 2631-37-0
Synonyms: Carbamic Acid, Methyl-, m-Cym-5-yl Ester; 3-Isopropyl-5-
Methylphenyl Methylcarbamate; 3-Methyl-5-(l-Methylethyl)Phenyl Methylcarbamate;
3-Methyl-5-Isopropylphenyl-N-Methylcarbamate; 5-Isopropyl-m-Tolyl Methyl-
carbamate; Carbamic Acid, (3-Methyl-5-(l-Methylethyl)Phenyl)-, Methyl Ester;
Carbamic Acid, N-Methyl-, 3-Methyl-5-Isopropylphenyl Ester; Carbamult;
Carbanilic Acid, 3-Isopropyl-5-Methyl-, Methyl Ester; ENT 27300; ENT 27300-A;
EP 316; m-Cym-5-yl Methylcarbamate; OMS 716; Promecarbe; SCH 34615; Schering
34615; Phenol, 3-Methyl-5-(l-Methylethyl)-,Methylcarbamate
Chemical Formula: C12H17NO2
Molecular Weight: 207.28
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral
(mouse) 16mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 243°F, 117°C at 0.01 mmHg (*Merck 1976)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00003 at 25°C (Worthing 1983)
Melting Point: 189-190°F, 87-87.5°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 2631-37-0
Page 2 of 4
PROMECARB
SECTION II (continued)
Solubility in Water: 92 mg/liter at room temperature (*Martin and
Worthing 1974)
Appearance and Odor: Almost odorless, colorless crystalline solid
(*Martin and Worthing 1974).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Doull 1980, p. 375)
Skin: Yes (Doull 1980, p. 375)
Ingestion: Yes (Doull 1980, p. 375)
Health Hazards (Acute, Delayed, and Chronic): Promecarb is highly toxic
by ingestion and is absorbed through the intact skin. ' It is a reversible
cholinesterase inhibitor and its effects are related to action on the
nervous sysem (Gosselin 1984, p. 11-308; *Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamates) Extinguish fire
using agent suitable for the surrounding fire, as the material itself burns
with difficulty. Use water in flooding quantities as a fog. Use alcohol
foam, carbon dioxide, or dry chemical (Student 1981, p. 104).
(Non-Specific - Carbamate Pesticide, Solid, n.o.s.) This material may
burn, but does not ignite readily. For small fires, use dry chemical,
carbon dioxide, water spray, or foam. For large fires, use water spray,
fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Stay upwind; keep out of low areas. Move container from
fire area if you can do it without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material.
Wear positive pressure breathing apparatus and special protective clothing
(DOT 1984, Guide 55).
-------
CAS Registry Number: 2631-37-0
Page 3 of 4
PROMECARB
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s.) Container may explode in heat of fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, no changes observed on storage for 140 hours at
50°C (122F) (*Martin and Worthing 1974).
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzed by alkalis (*Merck
1976).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Non-systemic contact insecticide (*Martin and Worthing 1974). Not for sale
or use in the USA (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Carbamate Pesticide, Solid, n.o.s.) Keep unnecessary
people away; isolate hazard areas and deny entry. Stay upwind and keep out
of low areas. Do not touch spilled material or breathe the dusts, vapors,
or fumes from burning materials. Use water spray to reduce vapors.
Do not handle broken packages without protective equipment. Wash
away any material that may have contacted the body with soap and water.
Take up small spills with sand or other noncombustible absorbent material
and place in containers for later disposal. Small dry spills: with clean
shovel place material into clean, dry container and cover; move containers
from spill area. Dike far ahead of large spills for later disposal
(Student 1981, p. 104; DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
-------
CAS Registry Number: 2631-37-0
Page 4 of 4
PROMECARB
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Diarrhea, nausea, vomiting, excessive
salivation, headache, pinpoint pupils and uncoordinated muscle movements
are all common symptoms of exposure to carbamate insecticides (*Rumack 1975
to Present).
Emergency and First Aid Procedures: Move the victim to fresh air and
monitor for respiratory distress. If a cough or difficulty in breathing
develops, be sure airways are clear and be prepared to provide oxygen.
Decontaminate the patient if there is any possibility of exposure to the
skin. Wash the skin and hair with soap and water at least twice. Remove
all contaminated clothing (*Rumack 1975 to Present; DOT 1984, Guide 55).
-------
CAS Registry Number: 2636-26-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CYANOPHOS
CAS Registry Number: 2636-26-2
Synonyms: (NIOSH/RTECS Synonyms, Volume 3, p. 154) Phosphorothioic Acid,
O,O-Dimethyl Ester, O-Ester with p-Hydroxybenzonitrile; BAY 34727; Bayer 34727;
Ciafos; O-p-Cyanophenyl O,O-Dimethyl Phosphorothioate; Cyanox; Cyap;
O,O-Dimethyl-O-p-Cyanophenyl Phosphorothioate; O,O-Dimethyl O-4-Cyanophenyl
Phosphorothioate; O,O-Dimethyl O-4-Cyanophenyl Thiophosphate; ENT 25,675;
Phosphorothioic Acid O-(4-Cyanophenyl) O,O-Dimethyl Ester; S 4084; Sumitomo S
4084; Sunitomo S 4084
Chemical Formula: C9H10NO,PS
Molecular Weight: 243.23
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral
(rat) 18 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 246-248°F, 119-120°C at 0.09 mmHg (Decomposes) (Merck
1983, p. 322)
Specific Gravity (H2O=1): 1.255-1.265 at 25°C/4°C (Worthing 1983,
P. 142)
Vapor Pressure (mmHg): 0.0008 at 20°C (Worthing 1983, p. 142)
Melting Point: 57-59°F, 14-15°C (Merck 1983, p. 322)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 2636-26-2
Page 2 of 4
CYANOPHOS
SECTION II (continued)
Solubility in Water: Slightly soluble (Merck 1983, p. 322)
Appearance and Odor: Yellow to reddish-yellow transparent liquid (Merck
1983, p. 322).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hayes, 1982, p. 301)
Skin: Yes (Hayes, 1981, p. 301)
Ingestion: Yes (Hayes, 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): Cyanophos is an
organophosphorus insecticide (Buchel 1983, p. 80). It is a cholinesterase
inhibitor (Merck 1983, p. 322). Death may occur after a massive oral dose;
with smaller accidental doses, onset of illness may be delayed (Hayes 1982,
p. 302).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn, but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move
container from fire area if you can do it without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire
and runoff from fire control water may produce irritating or poisonous
gases (DOT 1984, Guide 55).
-------
CAS Registry Number: 2636-26-2
Page 3 of 4
CYANOPHOS
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (Merck 1983, p. 322)
Stable:
Conditions to Avoid: Rapidly decomposes under alkaline conditions and
upon exposure to light (Merck 1983, p. 322).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE" INFORMATION
This material is an insecticide (Merck 1983, p. 322) used against rice stem
borers and house flies (Buchel 1983, p. 80). Not registered as a pesticide
in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material. Use water spray to reduce vapors. Take up small spills with
sand or other noncombustible absorbent material and place in containers for
later disposal. Dike far ahead of large spills for later disposal (DOT
1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2636-26-2
Page 4 of 4
CYANOPHOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of organophosphorus pesticide
poisoning include: headache, giddiness, nervousness, blurred vision,
weakness, nausea, cramps, diarrhea, and discomfort in the chest. Signs
include: sweating, pinpoint pupils, tearing, salivation and other
excessive respiratory tract secretion, vomiting, cyanosis, papilledema,
uncontrollable muscle twitches followed by muscular weakness, convulsions,
coma, loss of reflexes, and loss of sphincter control (Hayes 1982, p. 301).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least IS minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Farm Chemicals Handbook 1984
Sax 1984
Weast 1979
Hawley 1981
Gosselin 1984
-------
CAS Registry Number: 2642-71-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - AZINPHOS-ETHYL
CAS Registry Number: 2642-71-9
Synonyms: Phosphorodithioic Acid, O,O-Diethyl Ester, S-Ester with
3-(Mercaptomethyl)-l,2,3-Benzotriazin-4(3H)-one; Ethyl Guthion;
3,4-Dihydro-4-oxo-3-Benzotriazinylmethyl O,O-Diethyl Phosphorodithioate;
Athyl-Gusathion; BAY 16259; Bayer 16259; Cotnion-Ethyl; Crysthion; ENT 22,014;
Ethyl Azinphos; Ethyl Gusathion; Ethyl Homolog of Guthion; Gusathion A;
Gusathion H and K; Gusation A; Guthion (Ethyl); O,O-Diethyl
S-(4-Oxobenzyltriazine-3-Methyl) Dithiophosphate; O,O-Diethyl
S-(4-Oxobenzotriazino-3-Methyl) Phosphorodithioate; Phosphorodithioic Acid,
O,O-Diethyl Ester, S-Ester With 3-(Mercaptomethyl)-l,2,3-Benzotriazin-
4(3H)-one; Phosphorodithioic Acid, O,O-Diethyl S-((4-oxo-l,2,3-Benzotriazin-
3(4H)-yl)Methyl) Ester; R 1513; S-(3,4-Dihydro-4-oxo-l,2,3-Benzotriazin-3-yl
Methyl) O,O-Diethyl Phosphorodithioate; Azinphos Ethyl Dithiophosphate
Chemical Formula: C12H16NSO3PS2
Molecular Weight: 345.38
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 7 nag/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 232°F, 111°C at 0.001 mmHg (*Worthing 1979)
Specific Gravity (H2O=1): 1.284 at 20°C/4°C (*Worthing 1979)
Vapor Pressure (mmHg): 0.00000022 at 20°C (*Worthing 1979)
Melting Point: 127°F, 53°C (*Farm Chemicals Handbook 1981)
-------
CAS Registry Number: 2642-71-9
Page 2 of 4
AZINPHOS-ETHYL
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Farm Chemicals Handbook 1981)
Appearance and Odor: Colorless crystals (*Farm Chemicals Handbook 1981)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
•
Health Hazards (Acute, Delayed, and Chronic): The systemic effects of
this compound are similar to parathion. It is an extremely potent systemic
toxicant via ingestion, inhalation and skin contact. It may cause death or
permanent injury after very short exposure to small quantities (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do so without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) When heated to decomposition, it emits very toxic fumes
of sulfur, phosphorus and nitrogen oxides (Sax 1984, p. 1355). Container
-------
CAS Registry Number: 2642-71-9
Page 3 of 4
AZINPHOS-ETHYL
/
SECTION IV (continued)
may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of nitrogen, phosphorous and sulfur oxides (Sax
1984, p. 1355).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is a non-systemic insecticide with good ovicidal properties and long
persistence. It is not registered for use in the U.S. (*SRI). Among other
crops, it is used on cotton, citrus, vegetables, potatoes, tobacco, rice,
and cereals (*Worthing 1979) to control caterpillars, beetles, aphids,
spiders and many other insects (*Farm Chemicals Handbook 1981).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean dry containers and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2642-71-9
Page 4 of 4
AZINPHOS-ETHYL
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
'Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: The symptoms are similar to parathion.
Nausea is often the first symptom followed by vomiting, abdominal cramps,
diarrhea and excessive salivation. Also common in inhalation exposure are
headache, giddiness, vertigo and weakness, nasal discharge and a sensation
of tightness in the chest. Other symptoms include blurring or dimness of
vision; tearing; eye muscle spasm and pain; pinpoint pupils; loss of muscle
coordination; slurring of speech; muscle twitching (especially tongue and
eyelids); difficulty in breathing; excessive secretions of mucous in mouth,
nose, and respiratory tract; convulsions and coma (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticides, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 2665-30-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHONOTHIOIC ACID, METHYL-,
O-(4-NITROPHENYL) O-PHENYL ESTER
CAS Registry Number: 266S-30-7
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 124) CP 40294; ENT
25,787; Monsanto CP-40294; Phosphonothioic Acid, Methyl-, O-(p-Nitrophenyl)
O-Phenyl Ester
Chemical Formula: C13H12NO4PS
Molecular Weight: 309.29
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 2665-30-7
Page 2 of 4
PHOSPHONOTHIOIC ACID, METHYL-, O-(4-NITROPHENYL) O-PHENYL ESTI
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific - Organic Phosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific ~ Organic Phosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Non-Specific — Organic Phosphorus
Pesticide) (Hayes 1982, p. 301)
SECTION V - HEALTH HAZARD DATA (Continued)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Organic
Phosphorus Insecticides) Organic phosphorus insecticides are absorbed by
the skin, as well as by the respiratory and gastrointestinal tracts. It is
a cholinesterase inhibitor (Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide) This
material may burn, but does not ignite readily. For small fires, use dry
chemical, carbon dioxide, water spray, or foam. For large fires, use water
spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide) Stay upwind; keep out of low areas. Move containers from fire
area if you can do so without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide) Container may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
-------
CAS Registry Number: 2665-30-7
Page 3 of 4
PHOSPHONOTHIOIC ACID, METHYL-, O-(4-NITROPHENYL) O-PHENYL ESTER
SECTION V (continued)
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Organic Phosphorus Insecticides) Do not touch spilled
material; stop leak if possible. Use water spray to reduce vapors. Absorb
spills with noncombustible absorbent material. For large spills dike far
ahead for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Organic Phosphorus
Insecticides) Symptoms are headache, giddiness, blurred vision,
nervousness, weakness, nausea, cramps, diarrhea, and discomfort in the
chest. Signs include sweating, tearing, salivation, vomiting, bluing of
the skin, convulsions, coma, loss of reflexes and loss of sphincter control
(Hayes 1982, p. 302).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide) Move victim to fresh air; call emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least 15 minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
-------
CAS Registry Number: 2665-30-7
Page 4 of 4
PHOSPHONOTHIOIC ACID, METHYL-, O-(4-NITROPHENYL) O-PHENYL ESTE
SECTION IX (continued)
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
COMMENTS
Sources searched, no information found:
Sax 1984
Merck 1983
Farm Chemicals Handbook 1984
Buchel 1983
Verschueren 1983
Weast 1979
Hawley 1981
Chemical structure indicates that this is an organic phosphorus pesticide.
-------
Sis,
CAS Registry Number: 2703-13-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHONOTHIOIC ACID, METHYL-, O-ETHYL
O-(4-(METHYLTHIO)PHENYL) ESTER
CAS Registry Number: 2703-13-1
Synonyms: (SANSS 1983 Synonyms) Bayer 29952; BAY 29952; ENT 25,612; O-Ethyl
O-[4-(Methylthio)Phenyl] Methylphosphonothioate; Phenol, p-(Methylthio)-O-Ester
with O-Ethyl Methylphosphonothioate; Phosphonothioic Acid, Methyl-, O-Ethyl
O-(p-(Methylthio)Phenyl) Ester
Chemical Formula: C10H15O2PS2
Molecular Weight: 262
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 2703-13-1
Page 2 of 3
PHOSPHONOTHIOIC ACID, METHYL-, O-ETHYL O-(4-(METHYLTHIO)PHENY
ESTER
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 2703-13-1
Page 3 of 3
PHOSPHONOTHIOIC ACID, METHYL-, O-ETHYL O-(4-(METHYLTHIO)PHENYL)
ESTER
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
RTECS 1983
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Physicians' Desk Reference 1985
Oilman 1985
DOT 1984
Hayes 1982
-------
CAS Registry Number: 2757-18-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THALLOUS MALONATE
CAS Registry Number: 2757-18-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p.637) Malonic Acid,
Thallium Salt (1:2); Formomalenic Thallium; Propanedioic Acid, Dithallium Salt;
Thallium Malonate
Chemical Formula: C3H2O4 2T1
Molecular Weight: 510.79
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 18.8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Thallium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 2757-18-8
Page 2 of 4
THALLOUS MALONATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Soluble Thallium Compounds) 0.1 mg/ms, as thallium (OSHA 1984,
p. 663)
ACGIH TLV: (Soluble Thallium Compounds) 0.1 mg/ms, as thallium (skin)
(ACGIH 1985, p. 31)
IDLH: Not Found
Other Limits Recommended: (IDLH for soluble thallium compounds) 20 mg/m3
(NIOSH 1987, p. 224)
Routes of Entry: Inhalation: Yes (Non-Specific — Thallium Salts,
n.o.s.) (DOT 1984, Guide 53)
Skin: Not Found
Ingestion: Yes (Non-Specific - Thallium Salts,
n.o.s.) (Gosselin 1984, p. III-379)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific - Thallium
Salts, n.o.s.) Poisonous if swallowed. Inhalation of dust causes
poisoning (DOT 1984, Guide 53).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Thallium Salts, n.o.s.) For
small fires use dry chemical, carbon dioxide, water spray, or foam. For
large fires use water spray, fog, or foam. Move container from fire area
if you can do so without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Thallium Salts,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing (DOT 1984,
Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Thallium Salts,
n.o.s.) Fire may produce irritating or poisonous gases. Runoff from fire
control or dilution water may cause pollution (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 2757-18-8
Page 3 of 4
THALLOUS MALONATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above).
(Non-Specific — Thallium Salts, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Thallium Salts,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 2757-18-8
Page 4 of 4
THALLOUS MALONATE
COMMENTS
Sources searched but no information found:
ACGIH 1983
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 2763-96-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MUSCIMOL
CAS Registry Number: 2763-96-4
Synonyms: 3-Isoxazolol, S-(Aminomethyl)-; 3(2H)-Isoxazolone,
5-(Aminomethyl)-; 3-Hydroxy-5-Aminomethylisoxazole; 3-Hydroxy-5-
Aminomethylisoxazole-Agarin; 5-(Aminomethyl)-3-Isoxazolol; 5-Aminomethyl-3-
Hydroxyisoxazole; 5-Aminomethyl-3-Isoxyzole; Agarin; Agarine; Pantherine
Chemical Formula: C4H6N2O2
Molecular Weight: 114.12
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 17 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 347°F, 175°C (decomposes) (Merck 1983, p. 903)
Vapor Density (AIR»1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (Gosselin 1984, p. 11-247)
Appearance and Odor: Crystals (*Merck 1976)
-------
CAS Registry Number: 2763-96-4
Page 2 of 3
MUSCIMOL
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 227)
Health Hazards (Acute, Delayed, and Chronic): This compound is a natural
constituent of amanita mushrooms and is extremely toxic. It is a potent
central nervous system depressant, and is believed to be responsible for
most of the nervous system effects that result from eating this mushroom
('Grant 1974; *Gilman 1980). The lowest toxic dose in humans has been
reported at 109 mg/kg (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 227).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 227).
-------
CAS Registry Number: 2763-96-4
Page 3 of 3
MUSCIMOL
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
I
Formerly used as a sedative and an antiemetic (*Merck 1976) and for
experimental laboratory purposes (*Peer Review Committee).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Muscimol is a potent central nervous
system depressant (*Merck 1976). Initially, drowsiness, stupor, or sleep
followed by mild nausea and vomiting, muscle spasms in extremities, various
emotional changes and distorted perceptions of space and time, but only
rarely hallucinations (Gosselin 1984, p. 11-247).
Emergency and First Aid Procedures: Treat as for general poisoning
(*Rumack 1975 to Present). Move victim to fresh air; call emergency
medical care. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site (DOT 1984, Guide 53).
-------
CAS Registry Number: 2778-04-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ENDOTHION
CAS Registry Number: 2778-04-3
Synonyms: Phosphorothioic Acid, O,O-Dimethyl Ester, S-Ester with
2-(Mercaptomethyl)-5-Methoxy-4H-Pyran-4-one; 2-(S-Dimethylphosphorothio-
methyl)-5-Methoxy-4-Pyrone; 5-Methoxy-2-(Dimethoxyphosphinylthioinethyl)
Pyrone-4; AC-18737; Endocid; Endocide; ENT 24653; Exothion; FMC 5767; NIA 5767;
Niagara 5767; O,O-Dimethyl Phosphorothioate, S-Ester with
2-(Mercaptomethyl)-5-Methoxy-4H-Pyran-4-one; O,O-Dimethyl S-(5-Methoxy-
4-oxo-4H-Pyran-2-yl) Phosphorothioate; O,O-Dimethyl S-(5-Methoxypyronyl-
2-Methyl) Thiophosphate; Phosphate 100; Phosphopyron; Phosphopyrone;
Phosphorothioic Acid, S-((5-Methoxy-4-oxo-4H-Pyran-2-yl)Methyl) O,O-Dimethyl
Ester; S-(5-Methoxy-4-Pyron-2-ylmethyl) Dimethyl Phosphorothioate;
S-5-Methoxy-4-Oxopyran-2-ylmethyl Dimethyl Phosphorothioate;
S-5-Methoxy-4-Pyron-2-ylmethyl O,O-Dimethyl Phosphorothioate;
S-[(5-Methoxy-4-Oxo-4H-Pyran-2-yl)Methyl] O,O-Dimethyl Phosphorothioate
Chemical Formula: C9H13O6PS
Molecular Weight: 280.24
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 17 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
-------
CAS Registry Number: 2778-04-3
Page 2 of 4
ENDOTHION
SECTION II (continued)
Melting Point: 205°F, 96°C (*Martin and Worthing 1974); 194-196°F,
90-91°C (Hawley 1981, p. 410)
Vapor Density (AIR-1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 150 g/100 ml at 68°F, 20°C (*Martin and Worthing
1974)
Appearance and Odor: White crystals, slight odor (*Martin and Worthing
1974).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
1DLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 1276)
Ingestion: Yes (Sax 1984, p. 1276)
Health Hazards (Acute, Delayed, and Chronic): This material is poisonous
to humans (Hayes 1982, p. 365). Its toxic effects are most likely related
to action on the nervous system (Clayton and Clayton 1982, p. 11-291).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 2778-04-3
Page 3 of 4
ENDOTHION
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Cylinder may explode in heat or fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of phosphorous oxides and sulfur oxides (Sax 1984,
p. 1276).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is a systemic insecticide (*Martin and Worthing 1974). It is
not sold in the USA or Canada (Hayes 1982, p. 365).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific ~ Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry containers and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 2778-04-3
Page 4 of 4
ENDOTHION
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include headache, dizziness,
nausea, salivation, vomiting, abdominal pain, diarrhea, chest pain, blurred
vision, muscle twitching, and weakness. Exposure may cause psychotic
behavior, loss of coordination, unconsciousness, and rarely, convulsions
(*Rumack 1975 to Present).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 3037-72-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SILANE, (4-AMINOBUTYL)DIETHOXYMETHYL-
CAS Registry Number: 3037-72-7
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 775): Butylamine,
4-(Diethoxymethylsilyl)-; (4-Aminobutyl)diethoxymethylsilane;
delta-Aminobutylmethyldiethoxysilane
Chemical Formula: C9H2SNO2Si
Molecular Weight: 205.42
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Unjler Section 302: LD50 dermal
(rat, mouse, rabbit) 45 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate-1): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 3037-72-7
Page 2 of 3
SILANE, (4-AMINOBUTYL)DIETHOXYMETHYL-
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 204)
Ingestion: Yes (Sax 19S4, p. 204)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic to skin, moderately toxic by ingestion and is a mild skin irritant
(Sax 1984, p. 204).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 204).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 204).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
-------
CAS Registry Number: 3037-72-7
Page 3 of 3
SILANE, (4-AMINOBUTYL)DIETHOXYMETHYL-
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid contact with skin (see Section HI above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Arena 1978
Doull 1980
Encyc Occupat Health and Safety 1983
NFPA 1984
Oilman 1985
Gosselin 1983
Hawley 1981
Hayes 1982
Merck 1983
Weiss 1980
Farm Chemicals Handbook 1984
NIOSH/OSHA 1978
ACGIH 1983
Weast 1979
Verschueren 1983
-------
CAS Registry Number: 3254-63-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHOSPHORIC ACID, DIMETHYL 4-(METHYLTHIO)
PHENYL ESTER
CAS Registry Number: 3254-63-5
Synonyms: Dimethyl p-(Methylthio)Pheiiyl Phosphate; 4-Methylthiophenyl
Dimethyl Phosphate; Allied GC 6506; ENT 25734; GC 6506; HA-1200; O,O-Dimethyl
O-(4-Methylmercaptophenyl) Phosphate; Phenol, p-(Methylthio)-, Dimethyl
Phosphate; Phosphoric Acid, Dimethyl p-(Methylthio)Phenyl Ester
Chemical Formula: C9H13O4PS
Molecular Weight: 248.25
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.273 at 21.4°C (*Worthing 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 9.8 mg/100 ml at room temperature ('Worthing 1979)
Appearance and Odor: Colorless liquid (*Worthing 1979)
-------
**,,:
CAS Registry Number: 3254-63-5
Page 2 of 4
PHOSPHORIC ACID, DIMETHYL 4-(METHYLTHIO) PHENYL ESTER
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2214)
Skin: Yes (Sax 1984, p. 2214)
Ingestion: Yes (Sax 1984, p. 2214)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by oral or
skin exposure (Sax 1984, p. 2214). Its effects are probably due to action
on the nervous system (Doull 1980, p. 371). This compound may cause death
through respiratory arrest (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: (Non-Specific - Organophosphorus Pesticide, Liquid,
n.o.s.) May burn but does not ignite readily (DOT 1984, Guide 55)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray,
or foam. Large fires: water spray, fog, or foam. Move container from
fire area if you can do it without risk. Fight fire from maximum distance
(DOT 1984 Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Wear positive pressure breathing apparatus and
special protective clothing. Dike fire control water for later disposal;
do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of sulfur oxides and phosphorus oxides (Sax 1984, p.
2214). (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Fire
and runoff from fire control water may produce irritating or poisonous
gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 3254-63-5
Page 3 of 4
PHOSPHORIC ACID, DIMETHYL 4-(METHYLTHIO) PHENYL ESTER
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Hydrolyzed by alkalies at 37.5°C
(* Worthing 1979).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of sulfur oxides and phosphorus oxides (Sax 1984, p.
2214).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
A contact and systemic insecticide and acaricide (*Worthing 1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticides) Keep material out of water
courses and sewer. Build dikes to contain flow as necessary. Use water
spray to knock down vapor. Do not touch spilled material (Student 1981,
p. 384). (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Large
spills: dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms are similar to those of
parathion. Common symptoms upon inhalation include: nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headaches, dizziness,
weakness, runny nose, and sensation of tightness in chest. Other symptoms
include: loss of muscle coordination, slurring of speech, mental
-------
CAS Registry Number: 3254-63-5
Page 4 of 4
PHOSPHORIC ACID, DIMETHYL 4-(METHYLTHIO) PHENYL ESTER
SECTION IX (continued)
confusion, and disorientation. Further exposure symptoms include
convulsions, loss of bladder control, random jerky movements, and coma
(*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. Remove and isolate contaminated clothing and
shoes at the site. In case of contact with material, immediately flush
skin or eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 3569-57-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFOXIDE, 3-CHLOROPROPYL OCTYL
CAS Registry Number: 3569-57-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 672) Sulfoxide,
3-Chloropropyl-n-Octyl-; 3-Chloropropyl-n-Octylsulfoxide, MGK Repellent 1,207
Chemical Formula: CnH23ClOS
Molecular Weight: 238.85
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 dermal
(rabbit) 8 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 3569-57-1
Page 2 of 3
SULFOXIDE, 3-CHLOROPROPYL OCTYL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 3569-57-1
Page 3 of 3
SULFOXIDE, 3-CHLOROPROPYL OCTYL
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENT
The following sources were searched but no information was found:
Clayton and Clayton 1981-82
Merck 1983
Sax 1984
Verschueren 1983
Weast 1979
Hayes 1981
Buchel 1983
Farm Chemicals Handbook 1984
DOT 1984
X —
-------
CAS Registry Number: 3615-21-2
Page 1 of 3
EPA CHEMICAL PROFILE
Date: June 22, 1987
Revision: November 30, 1987
CHEMICAL IDENTITY -- BENZIMIDAZOLE, 4,5-DICHLORO-2-(TRIFLUOROMETHYL)-
CAS Registry Number: 3615-21-2
Synonyms: Chlorflurazole; Chloroflurazole;
4,5-Dichloro-2-Trifluoromethylbenzimidazole;
IH-Benzimidazole, 4,5-dichloro-2-(Trifluoromethyl)-; NC 3363;
4,5-Dichloro-2-(Tr if luoromethy 1)-1 H-Benzimidazole;
4,5-Dichloro-2-(Trifluoromethyl)benzimidazole
Chemical Formula: C8H3C12F3N2
Molecular Weight: 255.03
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
13.08 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00004 mmHg (5.3 mPa) at 22.5°C (*Spencer 1982)
Melting Point: 415-417°F, 213-214°C (*Spencer 1982)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 69 ppm (§> 25°C (*Spencer 1982)
-------
CAS Registry Number: 3615-21-2
Page 2 of 3
BENZIMIDAZOLE, 4,5-DICHLORO-2-(TRIFLUOROMETHYL)-
SECTION II (continued)
Appearance and Odor: Crystalline solid, fine white needles when pure;
brownish commercial material (*Spencer 1982)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: (Non-Specific -- Pesticide, solid, n.o.s.)
Yes (DOT 1984, Guide 53)
Skin: Not Found
Ingestion: (Non-Specific -- Pesticide, solid, n.o.s.)
Yes (DOT 1984, Guide 53)
Health Hazards (Acute, Delayed, and Chronic): (Non-specific — Pesticide,
solid, n.o.s.) Poisonous if swallowed. Inhalation of dust poisonous
(DOT 1984, Guide 53).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): (Non-Specific -- Pesticide, solid, n.o.s.)
May burn, but does not ignite readily (DOT 1984, Guide 53).
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Pesticide, solid, n.o.s.)
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Pesticide, solid,
n.o.s.) Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Wear self-contained (positive
pressure if available) breathing apparatus and full protective clothing
(DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: (Non-Specific - Pesticide, solid,
n.o.s.) Fire may produce irritating or poisonous gases. Runoff from fire
control or dilution water may cause pollution (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
-------
\
CAS Registry Number: 3615-21-2
Page 3 of 3
BENZIMIDAZOLE, 4,5-DICHLORO-2-(TRIFLUOROMETHYL)-
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1982)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Amine salts of hormone herbicides,
alkali-unstable fungicides or insecticides (*Spencer 1982)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an herbicide (*Farm Chemicals Handbook 1984).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Pesticide, solid, n.o.s.) Do not touch spilled material;
stop leak if you can do it without risk. Small spills: take up with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 53).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific — Pesticide, solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove
and isolate contaminated clothing and shoes at the site. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 3689-24-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFOTEP
CAS Registry Number: 3689-24-5
Synonyms: Thiopyrophosphoric Acid, Tetraethyl Ester; Dithion;
Di(thiophosphoric)Acid, Tetraethyl Ester; Dithio; Dithiodiphosphoric Acid,
Tetraethyl Ester; Dithiofos; Dithione; Dithiophos; ASP 47; Bay-E-393;
Bis-O,O-Diethylphosphorothionic Anhydride; Bladafum; Pirofos; Plant Dithio
Aerosol; Plantfume 103 Smoke Generator; Pyrophosphoric Acid, Dithiono-,
Tetraethyl Ester; Pyrophosphorodithioic Acid, O,O,O,O-Tetraethyl Ester;
Pyrophosphorodithioic Acid, Tetraethyl Ester; Sulfatep; Sulfotepp; Sulphatep;
TEDP; TEDTP; Tetraethyl Dithio Pyrophosphate, Liquid (DOT); Tetraethyl
Dithionopyrophosphate; Tetraethyl Dithiopyrophosphate; Tetraethyl
Thiodiphosphate; Tetraethyl Thiopyrophosphate; Thiodiphosphoric Acid
[((HO)2P(S))2O], Tetraethyl Ester; Thiopyrophosphoric Acid [((HO)2PS)2O],
Tetraethyl Ester; Thiopyrophosphoric Acid, Tetraethyl Ester; Thiotep; Thiotepp
Chemical Formula: C8H20O5P2Sj
Molecular Weight: 322.32
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.038 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 277-282°F, 136-139°C at 2 mmHg (*Weast 1979)
Specific Gravity (H2O=1): 1.196 at 25°C (*Weast 1974)
Vapor Pressure (mmHg): 0.00017 at 20°C (*Worthing 1979)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 3689-24-5
Page 2 of 4
SULFOTEP
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 25 mg/liter at room temperature (Worthing 1983)
Appearance and Odor: Colorless oil (*Weast 1979); pale yellow mobile
liquid (*Worthing 1979); garlic odor (*ACGIH 1980)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.2 mg/ms (skin) (*NIOSH/OSHA 1978)
ACGIH TLV: TWA 0.2 mg/m3 (skin) (ACGIH 1986-87, p. 30)
IDLH: 35 mg/ms (*NIOSH/OSHA 1978)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 981)
Skin: Yes (Sax 1984, p. 1395)
Ingestion: Yes (Sax 1984, p. 1395)
Health Hazards (Acute, Delayed, and Chronic): Super toxic; probable oral
lethal dose in humans is less than 5 mg/kg, or a taste (less than 7 drops)
for a 70 kg (150 Ib.) person (*Gosselin 1976). It is a cholinesterase
inhibitor (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not combustible (NIOSH/OSHA 1978, p. 172)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
n.o.s.) For small fires, use dry chemical, carbon dioxide, water spray, or
foam. For large fires, use water spray, fog, or foam. Fight fire from
maximum distance (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55);
Unusual Fire and Explosion Hazards: When heated to decomposition, emits
highly toxic fumes of phosphorus oxides and sulfur oxides (*Sax 1979).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 3689-24-5
Page 3 of 4
SULFOTEP
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1973)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
p. 172). Technical products corrosive to iron ('Worthing 1979).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide; acaricide (*Farm Chemicals Handbook 1981); mitocide (Merck
1983, p. 1287).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphate Pesticide) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Remove and isolate
contaminated clothing at the site. Do not touch spilled material; stop
leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other noncombustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Material is similar to parathion in
symptomatology, including nausea followed by vomiting, abdominal cramps,
diarrhea, excessive salivation, headache, giddiness, dizziness, weakness,
-------
CAS Registry Number: 3689-24-5
Page 4 of 4
SULFOTEP
SECTION IX (continued)
tightness in chest, blurring of vision, tearing, slurring of speech,
confusion, difficulty breathing, convulsions, coma and even death
(*Gosselin 1976).
Emergency and First Aid Procedures: Emergency treatment is similar to
that for parathion poisoning (*Rumack 1975 to Present) and includes:
moving victim to fresh air and calling emergency medical care. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush skin or eyes
with running water for at least IS minutes. Speed in removing material
from skin is of extreme importance. Remove and isolate contaminated
clothing and shoes at the site. Keep victim quiet and maintain normal body
temperature. Effects may be delayed; keep victim under observation (DOT
1984, Guide 55).
-------
CAS Registry Number: 3691-35-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLOROPHACINONE
CAS Registry Number: 3691-35-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, pp. 514-515)
1,3-Indandione, 2-((p-Chlorophenyl)Phenylacetyl-; 2-[(4-Chloropheny 1)
Phenylacety 1]-1 H-indene-1,3(2H)-dione; 2-[(p-chlorophenyl)phenyl- acety 1]-
1,3-indandione; LM91; CAID; Drat; Liphadione; Quick; Raviac; Rozol; Delta;
Microzul; Muriol; 2-(2-Phenyl-2-(4-chlorophenyl)acetyl)-1,3-Indandione;
Ramucide; Ranac; Ratomet; Topitox; lH-Indene-l,3(2H)-Dione,
2-[(4-Chlorophenyl)Phenylacetyl]-; Afnor; 2-(alpha-p-Chlorophenylacetyl)Indane-
1,3-Dione; 2(2-(4-Chlorophenyl)-2-Phenylacetyl)Indan-l,3-Dione
Chemical Formula: C23H15C1OS
Molecular Weight: 374.82
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 1.06 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 284°F, 140°C (Merck 1983, p. 302)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 3691-35-8
Page 2 of 3
CHLOROPHACINONE
SECTION II (continued)
Solubility in Water: Very sparingly soluble (Merck 1983, p. 302)
Appearance and Odor: Crystals (Merck 1983, p. 302). Commercially
available as oil concentrate and as dust concentrate (Gosselin 1984, p.
11-348).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 749)
Ingestion: Yes (Sax 1984, p. 749)
Health Hazards (Acute, Delayed, and Chronic): Chlorophacinone is highly
toxic orally and by skin absorption (Sax 1984, p. 749). The probable oral
lethal dose for humans is less than 5 mg/kg to 50 mg/kg, or between a taste
(less than 7 drops) and 1 teaspoonful for a ISO Ib. (70 kg) person
(Gosselin 1984, p. IM335).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Coumarin Derivative Pesticide,
Solid, n.o.s.) Small fires: dry chemicals, carbon dioxide, water spray or
foam. Large fires: water spray, fog or foam. Move container from fire
area if you can do so without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) Container may explode in heat of fire. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Wear
positive pressure breathing apparatus and special protective clothing.
Remove and isolate contaminated clothing at the site. If water pollution
occurs, notify appropriate authorities (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Coumarin Derivative
-------
CAS Registry Number: 3691-35-8
Page 3 of 3
CHLOROPHACINONE
SECTION IV (continued)
Pesticide, Solid, n.o.s.) Fire may produce irriating or poisonous gases.
Runoff from fire control water may give off poisonous gases. Runoff from
fire control or dilution water may cause pollution (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated it emits toxic fumes
of chlorides (Sax 1984, p. 748).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Anticoagulant rodenticide (Merck 1983, p. 302). Chronic acting, multiple
dose rodenticide (Buchel 1983, p. 222).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Coumarin Derivative, Pesticide, Solid, n.o.s.) Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 3691-35-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
CHLOROPHACINONE
(3691-35-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Yellow crystals.
Commercial Forms - Oil, powder.
Use - Rodenticide.
Other Names - 2-(p-Chlorophenyl)phenylacetyl-l,3-indandione; Drat; liphadione;
Quick; Raviac; Topitox.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, DSW, Ringer's lactate,
Vitamin K (phytonadione).
Signs and Symptoms of Acute Chlorophacinone Exposure:
Warning: Highly toxic by skin absorption.
Chlorophacinone is an anticoagulant. Hemorrhage is the most common sign and
may be manifested by nose and gum bleeding, bloody stools and urine, ecchymoses
(extravasations of blood into skin), and hemoptysis (coughing up of blood).
Bruising is heightened. Abdominal and flank pain may also occur.
-------
EFATG
CAS Registry Number: 3691-35-8
Page 2 of 3
CHLOROPHACINONE
Emergency Life-Support Procedures:
t
Acute exposure to chlorophacinone may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be used, as necessary. Rescue
vehicle should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to chlorophacinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to chlorophacinone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 3691-35-8
Page 3 of 3
CHLOROPHACINONE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of chlorophacinone is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 3734-97-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - AMITON OXALATE
CAS Registry Number: 3734-97-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 150) Phosphorothioic
Acid, S-(2-Diethylamino)ethyl) O,O-Diethyl Ester, Oxalate (1:1); Chipman 6199;
Chipman R-6,199; Citram; S-(2-Diethylaminoethyl) O,O-Diethylphosphorothioate
Hydrogenoxalate; O,O-Diethyl-S-(2-Diethylamino) Ethylphosphorothioate Hydrogen
Oxalate; O,O-Diethyl S-(beta-Diethylamino)Ethyl Phosphorothiolate Hydrogen
Oxalate; O,O-Diethyl S-(2-Ethyl-N,N-Diethylamino) Phosphorothioate Hydrogen
Oxalate; ENT 20,993; Hydrogen Oxalate of Amiton; Tetram 75; Tetram, Acid
Oxalate; Tetram Monooxalate
Chemical Formula: C10H24NOSPS-C2H2O4
Molecular Weight: 359.42
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral (rat)
3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 208-210°F, 98-99°C (Merck 1983, p. 73)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
V
-------
CAS Registry Number: 3734-97-2
Page 2 of 4
AMITON OXALATE
SECTION II (continued)
Solubility in Water: Not Found
Appearance and Odor: Crystals (Merck 1983, p. 73)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 1009)
Skin: Yes (Non-Specific — Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Hawley 1981, p. 1009)
Health Hazards (Acute, Delayed, and Chronic): It is a cholinesterase
inhibitor (Hawley 1981, p. 1009).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Wear positive pressure breathing apparatus and special
protective clothing. Move container from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
V
-------
CAS Registry Number: 3734-97-2
Page 3 of 4
AMITON OXALATE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as an insecticide (Hawley 1981, p. 1009).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills; with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 3734-97-2
Page 4 of 4
AMITON OXALATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Organophosphorus
Pesticide) Symptoms include headache, giddiness, nervousness, blurred
vision, weakness, nausea, cramps, diarrhea, and discomfort in the chest.
Signs include sweating, miosis, tearing, salivation and other excessive
respiratory tract secretion, vomiting, cyanosis, uncontrollable muscle
twitching followed by muscular weakness, convulsions, coma, loss of
reflexes, and loss of muscular control (Hayes 1982, p. 301).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least IS minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
The following sources were searched but no information was found:
Sax 1984
NFPA 1984
ACGIH 1983-1984
NIOSH/OSHA 1978
Farm Chemicals Handbook 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Weast 1979
Doull 1980
Arena 1979
-------
CAS Registry Number: 3735-23-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- METHYL PHENKAPTON
CAS Registry Number: 3735-23-7
Synonyms (NIOSH-RTECS 1983 Synonyms, Volume 3, p. 140): Phosphorodithioic
Acid, S-(((2,5-Dichlorophenyl)Thio)Methyl) O,O-Dimethyl Ester; S-(((2,5-
Dichlorophenyl)Thio)Methyl) O,O-Dimethyl Phosphorodithioate; O,O-Dimethyl
S-(2,5-Dichlorophenylthio)Methyl Phosphorodithioate; ENT 25,554-X; G 30494;
Geigy 30494; Methanethiol, ((2,5-Dichlorophenylthio)-, S-Ester with
O,O-Dimethyl Phosphorodithioate; Methyl Phencapton
Chemical Formula: C9H11C12O2PS3
Molecular Weight: 349.25
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 11 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 3735-23-7
Page 2 of 4
METHYL PHENKAPTON
SECTION II (continued)
Appearance and Odor: Not Found
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Non-Specific — Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Organic
Phosphorus Insecticides) Organic phosphorus insecticides are absorbed by
the skin, as well as by the respiratory and gastrointestinal tracts (Hayes
1982, p. 301). Toxic hazard rating (oral) is high (Sax 1984, p. 1904).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Cylinder may explode in heat of fire (DOT 1984, Guide
55). Heat may cause decomposition and evolution of highly toxic fumes of
phosphorus oxides and chlorides (Sax 1984, p. 1904).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 3735-23-7
Page 3 of 4
METHYL PHENKAPTON
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Acaricide, insecticide (Farm Chemicals Handbook 1984, p. C-150). Not
registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry containers and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 3735-23-7
Page 4 of 4
METHYL PHENKAPTON
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Organic Phosphorus
Insecticides) Symptoms are secondary to cholinesterase inhibition,
headache, giddiness, blurred vision, nervousness, weakness, nausea, cramps,
diarrhea, and discomfort in the chest. Signs include sweating, tearing,
salivation, vomiting, cyanosis, convulsions, coma, loss of reflexes and
loss of sphincter control (Hayes 1982, p. 302).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Buchel 1983
Clayton and Clayton 1981-82
Weast 1979
Hawley 1981
Encyc Occupat Health and Safety 1983
-------
CAS Registry Number: 3878-19-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FUBERIDAZOLE
CAS Registry Number: 3878-19-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 577) Benzimidazole,
2-(2-Furyl)-; B-33172; BAY 33172; Bayer 33172; IH-Benzimidazole,
2-(2-Furanyl)-; Fuberidatol; Fuberisazol; Fubridazole; Furidazol; Furidazole;
2-(2-Furyl)Benzimidazole; 2-(2'-Furyl)-Benzimidazole; Voronit; Voronite;
W VII/117
Chemical Formula: CUH8N2O
Molecular Weight: 184.21
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(rat) 0.33 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 543-550°F, 284-288°C (Farm Chemicals Handbook 1984,
p. C108); 280°C decomposes (Worthing 1983, p. 296)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Practically insoluble (Farm Chemicals Handbook 1984,
p. C108)
-------
CAS Registry Number: 3878-19-1
Page 2 of 4
FUBERIDAZOLE
SECTION II (continued)
Appearance and Odor: Crystalline powder (Farm Chemicals Handbook 1984, p.
C108)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1465)
Skin: Yes (Sax 1984, p. 1465)
Ingestion: Yes (Sax 1984, p. 1465)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
moderately toxic. Its probable oral lethal dose in humans is 0.5-5 g/kg or
between 1 ounce and 1 pint for a 70 kg (150 Ib.) person (Gosselin 1984, p.
11-315).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a fungicide (Buchel 1983, p.
314). Extinguish with dry chemical, carbon dioxide, water spray, fog, or
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is a fungicide (Buchel
1983, p. 314). Move container from fire area if you can do so without
risk. Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Wear positive pressure
breathing apparatus and special protective clothing. Remove and isolate
contaminated clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1465).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 3878-19-1
Page 3 of 4
FUBERIDAZOLE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1465).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Uses include cereal seed dressing (Buchel 1983, p. 314); and fungicidal
non-mercurial seed dressing with special action against f usarium (Farm
Chemicals Handbook 1984, p. C108). Not registered as a pesticide in the
U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is a fungicide (Buchel 1983, p. 314). Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: This compound is a fungicide (Buchel
1983, p. 314). Move victim to fresh air; call emergency medical care. If
-------
CAS Registry Number: 3878-19-1
Page 4 of 4
a
FUBERIDAZOLE
SECTION IX (continued)
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Hawley 1981
Merck 1983
Hayes 1982
Weiss 1980
Weast 1979
DASE 1980 •
ACGIH 1983
NIOSH/OSHA 1978
Student 1981
Clayton and Clayton 1981-82
Doull 1980
NFPA 1984
Verschueren 1983
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 4044-65-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - BITOSCANATE
CAS Registry Number: 4044-65-9
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 585) Isothiocyanic Acid,
1,4-Phenylenedi-; Biscomate; 1,4-Diisothiocyanatobenzene; Isothiocyanic Acid
p-Phenylene Ester; Jonit; Phenylenc-l,4-Diisothiocyanate; Phenylene Thiocyanate
Chemical Formula: C8H4N2S2
Molecular Weight: 192.26
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral (rat)
21 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 270°F, 132°C (Sax 1984, p. 2185)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Odorless, colorless crystals (Sax 1984, p. 2185).
-------
CAS Registry Number: 4044-65-9
Page 2 of 3
BITOSCANATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (NIOSH/RTECS 1983, Volume 2, p. 585)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic if ingested. It is a central nervous system and gastrointestinal
toxin in humans (Sax 1984, p. 2185).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
2185).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
-------
CAS Registry Number: 4044-65-9
Page 3 of 3
BITOSCANATE
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Preparation and use as anthelmintic (Merck 1983, p. 182).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific — Cyanide or Cyanide
Mixture, Dry) Move victim to fresh air; call emergency medical care. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed, keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Weast 1979
Hayes 1975
Doull 1975
Weiss 1980
Verschueren 1983
Clayton and Clayton 1981-82
Physicians' Desk Reference 1985
Student 1981
NFPA 1984
Hayes 1982
Farm Chemicals Handboook 1984
Hawley 1981
-------
CAS Registry Number: 4098-71-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ISOPHORONE DIISOCYANATE
CAS Registry Number: 4098-71-9
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 556): Isocyanic Acid,
Methylene(3,5,5-Trimethyl-3,l-Cyclohexylene) Ester; Cyclohexane, 5-Isocyanato-
l-(Isocyanatomethyl)-l,3,3-Trimethyl-; IPDI; 3-Isocyanatomethyl-3,5,5-
Trimethylcyclohexylisocyanate; Isophorone Diamine Diisocyanate
Chemical Formula: C12H18N2O2
Molecular Weight: 222.32
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.26 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 4098-71-9
Page 2 of 4
ISOPHORONE DIISOCYANATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.09 mg/ms (0.01 ppm) (skin); to be changed to TWA 0.045
mg/m3 (0.005 ppm) (ACGIH 1986-87, pp. 21 and 36)
IDLH: Not Found
Other Limits Recommended: Occupational exposure to diisocyanates
recommended standard - Air: TWA 5 ppb; Ceiling limit 20 ppb/10 minutes
(NIOSH/RTECS 1983, Volume 2, p. 556).
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1648)
Skin: Yes (Sax 1984, p. 1648)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by inhalation and moderately toxic through the skin (Sax 1984, p.
1648).
Medical Conditions Generally Aggravated by Exposure: (Non-Specific --
Isocyanates) People with skin or respiratory problems should avoid
exposure (Encyc Occupat Health and Safety 1983, p. 1162).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog or foam. Move container
from fire area if you can do so without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Remove and isolate contaminated
clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1648).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 4098-71-9
Page 3 of 4
ISOPHORONE DIISOCYANATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of nitrogen oxides (Sax 1984, p. 1648).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other non-combustible absorbent material
and place into containers for later disposal. Small dry spills: with clean
shovel place material into clean, dry container and cover; move containers
from spill area. Large spills: dike far ahead of spill for later disposal
(DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Isocyanates)
Isocyanates can cause itching and skin rashes, tearing of the eyes,
inflammation of the mucous membrane of the nose, and lung problems (Encyc
Occupat Health and Safety 1983, p. 1161).
-------
CAS Registry Number: 4098-71-9
Page 4 of 4
ISOPHORONE DIISOCYANATE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 4104-14-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHOSACETIM
CAS Registry Number: 4104-14-7
Synonyms: Phosphoramidothioic Acid, Acetimidoyl-, O,O-bis(p-Chlorophenyl)
Ester; BAY 38819; Bayer 38819; DRC-714; Gophacide; Phosazetim;
Phosphoramidothioic Acid, (1-Iminoethyl)-, O,O-bis(4-Chlorophenyl) Ester
Chemical Formula: C14H1SC12N2O2PS
Molecular Weight: 375.22
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
3.7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 4104-14-7
Page 2 of 3
PHOSACETIM
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 464)
Ingestion: Yes (Sax 1984, p. 464)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic by mouth and
skin exposure (Sax 1984, p. 464).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, emits
toxic fumes, primarily chlorides and oxides of nitrogen, sulfur and
phosphorus (Sax 1984, p. 464).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Extreme heat (Sax 1984, p. 464)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition,
emits toxic fumes, primarily chlorides and oxides of nitrogen, phosphorus
and sulfur (Sax 1984, p. 464).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
-------
CAS Registry Number: 4104-14-7
Page 3 of 3
PHOSACETIM
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid skin contact (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
DOT 1984
Hawley 1981
Hayes 1982
Merck 1983
-------
CAS Registry Number: 4170-30-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CROTONALDEHYDE
CAS Registry Number: 4170-30-3
Synonyms: 2-Butenal; Crotonal; Crotonic Aldehyde; Crotylaldehyde
Chemical Formula: C4H6O
Molecular Weight: 70.09
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.2 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 219°F, 104°C (*Merck 1976)
Specific Gravity (H2O=1): 0.853 at 20°C (*Merck 1976)
Vapor Pressure (mmHg): 19 at 20°C/20°C (*Merck 1976)
Melting Point: -105°F, -76.5°C (*Merck 1976)
Vapor Density (AIR=1): 2.41 ('Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate-1): Not Found
Solubility in Water: 18.1 g/100 mL (Merck 1983, p. 372)
Appearance and Odor: Water-white to straw-colored liquid (*NFPA 1978);
pungent, suffocating odor (*Hawley 1977).
-------
CAS Registry Number: 4170-30-3
Page 2 of 4
CROTONALDEHYDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Gosselin 1976, p. 11-186)
Skin: Yes (Gosselin 1976, p. 11-186)
Ingestion: Yes (Gosselin 1976, p. 11-186)
Health Hazards (Acute, Delayed, and Chronic): This compound is an extreme
eye, respiratory, and skin irritant and can cause corneal damage (*NFPA
1978). A 15 minute exposure at 4.1 ppm is highly irritating to the nose
and upper respiratory tract and causes tearing. Brief exposure at 45 ppm
proved very disagreeable with prominent eye irritation (*ACGIH 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 55°F (OC) (*Hawley 1977)
Flammable Limits:
LEL: 2.95% v/v (Merck 1983, p. 372)
UEL: 15.5% v/v (Merck 1983, p. 372)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray and foam. Large fires: water spray, fog or foam (DOT 1984, Guide
28).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and full protective clothing. Move container from fire area if
you can do so without risk. Dike fire control water for later disposal; do
not scatter the material. Spray cooling water on containers that are
exposed to flames until well after fire is out. Withdraw immediately in
case of rising sound from venting safety device or any discoloration of
tank due to fire. Isolate for one-half mile radius if tank car or truck is
involved in fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: Flammable/combustible material; may
be ignited by heat, sparks or flames. Vapor may travel to a source of
ignition and flash back. Container may explode in heat of fire. Vapor
explosion and poison hazard indoors, outdoors or in sewers. Runoff to
sewer may create fire or explosion hazard.
NFPA Flammability Rating: 3
-------
CAS Registry Number: 4170-30-3
Page 3 of 4
CROTONALDEHYDE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1976)
Conditions to Avoid: Readily resinifies to dimer when pure and slowly
oxidizes to crotonic acid (*Merck 1976). Altered by light and air
(*Hawley 1977).
Incompatibility (Materials to Avoid): Readily converted by oxygen to
hazardous peroxides and acids (*NFPA 1978) and is incompatible with
caustics, ammonia, organic amines, mineral acids, and strong oxidizers
(NIOSH/OSHA 1978, p. 72).
Hazardous Decomposition or Byproducts: Peroxides and acids (*NFPA 1978).
Hazardous Polymerization: May Occur: Yes (*NFPA 1978)
May Not Occur:
Conditions to Avoid: Polymerization may take place at high
temperatures (*NFPA 1978).
SECTION VI - USE INFORMATION
Chemical intermediate for n-butanol, n-butyraldehyde, crotonic acid, and
sorbic acid (*SRI); intermediate for 2-ethylhexyl alcohol, solvent,
insecticides, tear gas, organic synthesis, and leather tanning (*Hawley
1977). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Shut off ignition sources; no flares,
smoking or flames in hazard area. Do not touch spilled material; stop leak
if you can do so without risk. Use water spray to reduce vapors. Small
spills: absorb with sand or other non-combustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 28).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 4170-30-3
Page 4 of 4
CROTONALDEHYDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED
CPE POOR/LIMITED
Neoprene POOR/LIMITED
Teflon GOOD/LIMITED
Viton POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Irritated eyes, repiratory distress, and
skin irritation (NIOSH/OSHA 1978, p. 72).
Emergency and First Aid Procedures: Exposed skin or eyes should be washed
with copious amounts of water for 15 minutes. Remove contaminated clothing
(*Rumack 1975 to Present). If not breathing, give artificial respiration.
If breathing is difficult, give oxygen. Keep victim quiet and maintain
normal body temperature. Effects may be delayed, keep victim under
observation (DOT 1984, Guide 28).
-------
CAS Registry Number: 4301-50-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FLUENETIL
CAS Registry Number: 4301-SO-2
Synonyms: (SANSS 1983 Synonyms) 4-Biphenylacetic Acid, 2-Fluoroethyl Ester;
[l,r-Biphenyl]-4-Acetic Acid, 2-Fluoroethyl Ester; beta-Fluoroethyl
4-Biphenylacetate; Fluenethyl; Lambrol; M 2060; Mytrol; TH 367-1; 2-Fluoroethyl
4-Biphenylacetate (ACN)
Chemical Formula: C16H15FO2
Molecular Weight: 258.31
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral (rat)
6 mg/kg ('NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 4301-50-2
Page 2 of 4
FLUENETIL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Fluenitil is highly toxic
to mammals (Buchel 1983, p. 177).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is an insecticide (Buchel 1983, p.
177). Methods for liquid insecticides are as follows. Small fires: dry
chemical, carbon dioxide, water spray, or foam. Large fires: water spray,
fog, or foam. Move container from fire area if you can do so without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This compound is an insecticide (Buchel
1983, p. 177). Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Remove and isolate contaminated clothing at the site
(DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 4301-50-2
Page 3 of 4
FLUENETIL
SECTION V (continued)
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material has been used as an acaricide and insecticide (Farm Chemicals
Handbook 1984, p. C-133). Its main use was as a dormant spray for orchard
fruit. It is no longer made (Buchel 1983, p. 177). Not registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is an insecticide (Buchel 1983, p. 177). Procedures for
liquid insecticides are as follows. Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Remove and isolate contaminated
clothing at the site. Do not touch spilled material; stop leak if you can
do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: This compound is an insecticide
(Buchel 1983, p. 177). For liquid insecticides, move victim to fresh air;
call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
V
-------
CAS Registry Number: 4301-50-2
Page 4 of 4
FLUENETIL
SECTION IX (continued)
be delayed; keep victim under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 4418-66-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHENOL, 2,2'-THIOBIS(4-CHLORO-6-METHYL-
CAS Registry Number: 4418-66-0
Synonyms: o-Cresol, 6,6'-Thiobis[4-Chloro-; Chlorbisan;
2,2'-Dihydroxy-3,3'-Dimethyl-5,5'-Dichlorodiphenyl Sulfide; Orbisan;
2,2'-Thiobis(4-Chloro-6-Methylphenol)
Chemical Formula: C14H12C12O2S
Molecular Weight: 315.22
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
1.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 175°C (Merck, p. 3928)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=I): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 4418-66-0
Page 2 of 3
PHENOL, 2,2'-THIOBIS(4-CHLORO-6-METHYL-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1068)
Health Hazards (Acute, Delayed, and Chronic): This compound is highly
toxic by ingestion (Sax 1984, p. 1068).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition it emits
very toxic fumes of sulfur oxides and chlorine containing compounds (Sax
1984, p. 1068).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of sulfur oxides and chlorine containing compounds
(Sax 1984, p. 1068).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 4418-66-0
Page 3 of 3
PHENOL, 2,2'-THIOBIS[4-CHLORO-6-METHYL-
SECTION VI - USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
The following sources were searched but no information found:
Hawley 1981
Hayes 1982
Merck Index 1983
Clayton and Clayton 1981-82
Buchel 1983
-------
CAS Registry Number: 4835-11-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - HEXAMETHYLENEDIAMINE, N,N'-DIBUTYL-
CAS Registry Number: 4835-11-4
Synonyms: N,N'-Dibutyl-l,6-Hexanediamine; 1,6-Hexanediamine, N,N'-Dibutyl-;
l,6-N,N'-Dibutylhexanediamine; N,N'-Dibutylhexamethylenediamine
Chemical Formula: C14H32N2
Molecular Weight: 228.42
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.22 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 204°C at 760 mmHg (Weast 1987, p. C303)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 4835-11-4
Page 2 of 4
HEXAMETHYLENEDIAMINE, N,N'-DIBUTYL-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Non-Specific -- Corrosive Alkali)
(Gosselin 1984, p. III-245)
Ingestion: Yes (Non-Specific — Corrosive Alkali)
(Gosselin 1984, p. III-245)
Health Hazards (Acute, Delayed, and Chronic): (Non-Sp*ecific — Corrosive
Alkali) Acute circulatory shock; burns in mouth, throat, and esophagus;
suffocation due to glottal or laryngeal swelling; perforation and
inflammation of the esophagus and the tracheobronchial tree; aspiration
pneumonia. Delayed stricture (scar) formation causing problems with
swallowing, and stomach filling and emptying; strong alkalis are markedly
corrosive and penetrating to skin and mucous membranes (Gosselin 1984, p.
III-245).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Alkylamine, n.o.s. (Corrosive))
This material may react violently with water. Small fires: dry chemical,
carbon dioxide, water spray, or foam. Large fires: water spray, fog, or
foam. Move container from fire area if you can do so without risk. Spray
cooling water on containers that are exposed to flames until well after
fire is out (DOT 1984, Guide 60).
Special Fire Fighting Procedures: (Non-Specific -- Alkylamine, n.o.s.
(Corrosive)) Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Wear self-contained (positive
pressure if available) breathing apparatus and full-protective clothing
(DOT 1984, Guide 60).
Unusual Fire and Explosion Hazards: (Non-Specific -- Alkylamine, n.o.s.
(Corrosive)) Flammable or poisonous gases may accumulate in tanks or
hopper cars (DOT 1984, Guide 60).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 4835-11-4
Page 3 of 4
HEXAMETHYLENEDIAMINE, N,N'-DIBUTYL-
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Alkylamine, n.o.s. (Corrosive)) Do not touch spilled
material; stop leak if you can do so without risk. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas (DOT 1984, Guide 60).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED**
Neoprene POOR/LIMITED**
PVC POOR/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 4835-11-4
Page 4 of 4
HEXAMETHYLENEDIAMINE, N,N'-DIBUTYL-
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This material is a corrosive alkali
(*Rumack 1975 to Present) By ingestion, visible burns in mouth, drooling,
gagging, vomiting, chest and upper abdominal pain, difficulty in breathing
or apnea (respiratory arrest), collapse and cardiac arrest may occur
(Gosselin 1984, p. III-245).
Emergency and First Aid Procedures: For oral ingestion, dilute
immediately with milk or water. Avoid vomiting. For inhalation exposure,
establish respiration and administer oxygen. For skin or eye exposure,
irrigate copiously with water for at least 15 minutes (*Rumack 1975 to
Present).
-------
CAS Registry Number: 5281-13-0
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PIPROTAL
CAS Registry Number: 5281-13-0
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 595) 1,3-Benzodioxole,
6-(bis(2-(2-Butoxyethoxy)Ethoxy)Methyl)-; Heliotropin Acetal; Piperonal
Bis(2-(2-Butoxyethoxy)ethyl)acetal; Tropital
Chemical Formula: C24H40O8
Molecular Weight: 456.64
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
4.4 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 5281-13-0
Page 2 of 3
PIPROTAL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 5281-13-0
Page 3 of 3
PIPROTAL
SECTION VI -- USE INFORMATION
Insecticide, structurally related to piperonyl butoxide (Hayes 1982,
p. 113). Synergist for pyrethroids (Buchel 1983, p. 21). Product
discontinued (Farm Chemicals Handbook 1984, p. C-236).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENT
Sources searched but no information was found:
Clayton and Clayton 1981-82
Merck 1983
Sax 1984
Verschueren 1983
Weast 1979
DOT 1984
-------
CAS Registry Number: 5344-82-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THIOUREA, (2-CHLOROPHENYL)-
CAS Registry Number: 5344-82-1
Synonyms: Urea, l-(o-Chlorophenyl)-2-Thio-; 2-Chlorophenylthiourea;
(o-Chloropheny l)thiourea; 1 -(2-Chloropheny l)thiourea; 1 -(o-Chloropheny 1)-
thiourea; N-(2-Chlorophenyl)thiourea; l-(2 Chlorophenyl)-2-Thiourea
Chemical Formula:
Molecular Weight: 186.67
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
4.6 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 294.8-295.7°F, 146-146.5°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Needles or plates (*Weast 1979)
-------
CAS Registry Number: 5344-82-1
Page 2 of 3
THIOUREA, (2-CHLOROPHENYL)-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 764)
Health Hazards (Acute, Delayed, and Chronic): High oral toxicity (Sax
1984, p. 764).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits very toxic fumes of chlorides, nitrogen oxides, and sulfur oxides
(Sax 1984, p. 764).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 5344-82-1
Page 3 of 3
THIOUREA, (2-CHLOROPHENYL)-
SECTION VI -- USE INFORMATION
This material is an herbicide (Iramer, C.R., Biochem. Physiol. Pflanz
117(6)515 (1982)). Not registered as a pesticide in the U.S. (USEPA/Active
Ingredients 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Thiourea) Do not touch spilled material; stop leak if you
can do it without risk. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX » EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific — Thiourea) Move
victim to fresh air; call emergency medical care. Remove and isolate
contaminated clothing and shoes at the site. In case of contact with
material, immediately flush skin or eyes with running water for at least 15
minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 5836-29-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - COUMATETRALYL
CAS Registry Number: 5836-29-3
Synonyms: 2H-1 -Benzopyran-2-one, 4-Hydroxy-3-( 1,2,3,4-Tetrahydro-1 -
Naphthalenyl)-; 3-(alpha-Tetral)-4-Oxycoumarin; 3-(alpha-Tetralyl)-4-
Hydroxycoumarin; 3-(D-Tetralyl)-4-Hydroxycoumarin; 4-Hydroxy-3-( 1,2,3,4-
Tetrahydro-1 -Naphthalenyl)-2H-1 -Benzopyran-2-one; 4-Hydroxy-3-( 1,2,3,4-
Tetrahydro- 1 -Naphthyl)-Cumarin; 4-Hydroxy-3-( 1,2,3,4-Tetrahydro-1 -
Naphthyl)Coumarin; Bayer 25 634; Coumarin, 4-Hydroxy-3-(l,2,3,4-Tetrahydro-l-
Naphthyl)-; Endox; Endrocid; Endrocide; Racumin; Racumin 57; Raucumin 57;
Rodentin
Chemical Formula: C19H16O3
Molecular Weight: 292.35
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
16.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 349°F, 176°C ('Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 5836-29-3
Page 2 of 4
COUMATETRALYL
SECTION II (continued)
Solubility in Water: Practically insoluble (*Worthing 1979)
Appearance and Odor: Yellowish-white crystalline powder; colorless when
pure; odorless ('Worthing 1979)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) (DOT 1984,
Guide 55)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
Ingestion: Yes (Physicians' Desk Reference 1980,
p. 1031)
Health Hazards (Acute, Delayed, and Chronic): Overdosage with
anticoagulants may cause acute bleeding (Physicians' Desk Reference 1980,
p. 1031).
Medical Conditions Generally Aggravated by Exposure: Pre-existing blood
clotting disease or liver disease (*Morgan 1976).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Coumarin Derivative Pesticide,
Solid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray or
foam. Large fires: water spray, fog or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) Stay upwind; keep out of low areas.' Wear
positive pressure breathing apparatus and special protective clothing.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) This material may burn but does not ignite
readily. Fire and runoff from fire control water may produce irritating or
poisonous gases. Runoff from fire control water may give off poisonous
gases. Container may explode in heat of fire (DOT 1984, Guide 55).
-------
CAS Registry Number: 5836-29-3
Page 3 of 4
COUMATETRALYL
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Enolic form of compound has acidic
properties and can form salts with metals (*Spencer 1982).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Courmatetralyl is used as a rodenticide (*Encyc Occupat Health and Safety
1971), functioning as an anticoagulant that does not induce bait-shyness
(* Worthing 1979).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Coumarin Derivative Pesticide, Solid, n.o.s.) Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not
touch spilled material. Use water spray to reduce vapors. With clean
shovel place material into clean, dry container and cover. Dike far ahead
of large spills for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED**
Butyl/Neoprene POOR/LIMITED**
-------
CAS Registry Number: 5836-29-3
Page 4 of 4
COUMATETRALYL
SECTION VIII (continued)
CPE GOOD/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
'Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Coumarin derivatives present no danger to
man under ordinary conditions of use, but can produce hemorrhage if
absorbed in large or repeated quantities (*Encyc Occupat Health and Safety
1971).
Emergency and First Aid Procedures: Ingestion: induce vomiting with
syrup of ipecac if victim ingested anticoagulant rodenticide within the
preceding 2-3 hours (Morgan 1976). (Non-Specific -- Coumarin Derivative
Pesticide, Solid, n.o.s.) Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least IS minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
\
-------
CAS Registry Number: 6533-73-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THALLOUS CARBONATE
CAS Registry Number: 6533-73-9
Synonyms: Thallium(I) Carbonate(2:l); Dithallium Carbonate; Carbonic Acid,
Dithallium (1+) Salt; Thallium Carbonate; Thallium Carbonate (T12CO3)
Chemical Formula: CO3 2T1
Molecular Weight: 468.78
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 21 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Thallium Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 7.1 (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: 522°F, 272°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate-1): Not Found
Solubility in Water: Soluble in 24 parts water, 3.7 parts boiling water
(*Merck 1976)
Appearance and Odor: Heavy, shiny, colorless or white crystals (*Hawley
1977)
-------
CAS Registry Number: 6533-73-9
Page 2 of 4
THALLOUS CARBONATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Thallium, soluble compounds) TWA 0.1 mg/m3, as thallium (NIOSH
1987, p. 224)
ACGIH TLV: (Thallium, soluble compounds) TWA 0.1 mg/ms, as thallium (skin)
(ACGIH 1986-87, p. 31)
IDLH: Not Found
Other Limits Recommended: IDLH for thallium, soluble compounds 20 mg/m3
(NIOSH 1987, p. 224)
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (Sax 1984, p. 2556)
Health Hazards (Acute, Delayed, and Chronic): Thallium is a digestive
tract irritant and nervous system toxicant (Doull 1980, p. 457). It is
classified as extremely toxic. Probable oral lethal dose (humans) is 5-50
mg/kg, or between 7 drops and 1 teaspoon for 70 kg person (150 Ib.)
(*Gosselin 1976). Teratogenic effects are noted after chronic intoxication
(*Venugopal 1978).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: •
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Thallium Salts, n.o.s.)
Extinguish with dry chemicals, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specif ic - Thallium Salts,
n.o.s.) Move container from fire area if you can do so without risk. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of thallium (Sax 1984, p. 2556). (Non-Specific --
Thallium Salts, n.o.s.) Fire may produce irritating or poisonous gases
(DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 6533-73-9
Page 3 of 4
THALLOUS CARBONATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of thallium (Sax 1984, p. 2556).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in the manufacture of imitation diamonds (*Merck 1976). Also used in
analysis to test for carbon disulfide (*Hawley 1977). Used as a fungicide
(*Venugopal 1978).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill. For small quantities, sweep onto paper or other
suitable material, place in sealed container for disposal. Large
quantities may be reclaimed. If this is not practical, collect in most
convenient and safe manner and deposit in sealed containers. For liquids
absorb in vermiculite, dry sand, earth or similar material and place in
sealed containers for disposal (*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
**Based on a chemical analog.
-------
CAS Registry Number: 6533-73-9
Page 4 of 4
THALLOUS CARBONATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms appear within 12-24 hours after
a single toxic dose or after several weeks of small daily doses. In acute
poisoning dominant symptoms include severe stomach cramps, vomiting and
diarrhea. In severe cases nervous system damage may be indicated by
tremors, delirium, convulsions, paralysis, and coma culminating in death.
Symptoms of subacute poisonings include stomach cramps, nausea, vomiting,
diarrhea, leg pains, tremors, and tingling sensations in the hands and
feet. Damage to nervous system may be permanent (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Thallium Salts,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contamiated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 6923-22-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MONOCROTOPHOS
CAS Registry Number: 6923-22-4
Synonyms: (E)-Dimethyl l-Methyl-3-(Methylamino)-3-Oxo-l-Propenyl Phosphate;
(E)-Phosphoric Acid Dimethyl Ester, Ester with 3-Hydroxy-N-Methylcrotonamide;
3-(Dimethoxyphosphinyloxy)-N-Methyl-cis-Crotonamide; 3-(Dimethoxyphosphinyloxy)
-N-Methylisocrotonamide; i-(Dimethoxyphosphinyloxy) N-Methyl-cis-Crotonamide;
3-Hydroxy-N-Methyl-cis-Crotonamide Dimethyl Phosphate; 3-Hydroxy-N-
Methylcrotonamide Dimethyl Phosphate; Azodrin; Azodrin Insecticide; Bilobran; C
1414; Ciba 1414; cis-l-Methyl-2-Methyl Carbamoyl Vinyl Phosphate; Crisodrin;
Crotonamide, 3-Hydroxy-N-Methyl-, Dimethylphosphate, (E)-; Dimethyl l-Methyl-2-
(Methylcarbamoyl)Vinyl Phosphate, cis-; Dimethyl 2-Methylcarbamoyl-l-
Methylvinyl Phosphate; Dimethyl Phosphate Ester of 3-Hydroxy-N-Methyl-cis-
Crotonamide; Dimethyl Phosphate of 3-Hydroxy-N-Methyl-cis-Crotonamide;
ENT 27,129; Monocron; N-Desmethyl Bidrin; N-Methyl Bidrin; Nuvacron; Nuvacron
20; Phosphoric acid, Dimethyl l-Methyl-3-(Methylamino)-3-Oxo-l-Propenyl Ester,
(E)-; Phosphoric Acid, Dimethyl Ester, Ester with (E)-3-Hydroxy-N-
Methylcrotonamide; Phosphoric acid, Dimethyl Ester, Ester with 3-Hydroxy-N-
Methylcrotonamide, (E)-; Phosphoric Acid, Dimethyl Ester, Ester with cis-3-
Hydroxy-N-Methylcrotonamide; Pillardrin; Plantdrin; SD 9129; Shell SD 9129;
Susvin
Chemical Formula: C7H14NO5P
Molecular Weight: 223.16
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.063 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 257°F, 125°C at 0.0005 mmHg (Worthing 1983)
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CAS Registry Number: 6923-22-4
Page 2 of 4
MONOCROTOPHOS
SECTION II (continued)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.000007 at 20°C (*Merck 1983)
Melting Point: 129-131°F, 54-55°C (crystals) (*Merck 1983); 77-86°F,
25-30°C (commercial product) (Merck 1983, p. 894)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible ('Merck 1983)
Appearance and Odor: Colorless crystals with a mild ester odor ('Hartley
1983; *Spencer 1982); commercial product is a reddish-brown solid (Merck
1983, p. 894)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.25 mg/m3 (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Farm Chemicals Handbook 1984)
Skin: Yes (Hayes 1982, p. 360)
Ingestion: Yes (Hayes 1982, p. 360)
Health Hazards (Acute, Delayed, and Chronic): Monocrotophos is an
organophosphorus pesticide. It is a cholinesterase inhibitor and acts on
the nervous system (Hayes 1982, p. 360). Extremely toxic; probable oral
lethal dose to humans 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70
kg (150 Ib.) person (*Gosselin 1984). Repeated inhalation or skin contact
with this material may, without symptoms, progressively increase
susceptibility to poisoning (*Farm Chemicals Handbook 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Above 200°F (CC) (Farm Chemicals Handbook
1984, p. C156)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Like other organophosphorus pesticides ('Morgan
1982) extinguish with dry chemical, carbon dioxide, water spray, fog, or
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CAS Registry Number: 6923-22-4
Page 3 of 4
MONOCROTOPHOS
SECTION IV (continued)
foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: Like other organophosphorus pesticides
(*Morgan 1982) move container from fire area if you can do so without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Wear positive pressure breathing
apparatus and full protective clothing ('Farm Chemicals Handbook 1984).
Container may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes. Unstable in aqueous solution above pH 7.0; in
low molecular weight alcohols and glycols ('Worthing 1979)
Stable: Yes. Stable in ketones and higher molecular weight
alcohols and glycols ('Worthing 1979).
Conditions to Avoid: Stable when stored in glass or polyethylene
containers. Relatively stable in sunlight (Farm Chemicals Handbook
1984, p. C156). Keep away from temperatures above 80°F; do not store
below 70°F. Corrosive to black iron, drum steel, stainless steel 304
and brass, but not to glass, aluminum, or stainless steel 316
('Worthing 1979).
Incompatibility (Materials to Avoid): Incompatible with alkaline
compounds ('Worthing 1979).
Hazardous Decomposition or Byproducts: Toxic fumes evolved when heated to
decomposition ('Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Monocrotophos is a fast acting insecticide with both systemic and contact
action used against a wide range of pests on cotton, sugar cane, tobacco,
potatoes, peanuts, tomatoes, and ornamentals ('Worthing 1979; 'Farm
Chemicals Handbook 1984).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
As with other organophosphorus pesticides ('Morgan 1982), do not
touch spilled material; stop leak if you can do it without risk.
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CAS Registry Number: 6923-22-4
Page 4 of 4
MONOCROTOPHOS
SECTION VII (continued)
Use water spray to reduce vapors. Small spills: take up with
sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal. Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 6923-22-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
MONOCROTOPHOS
t
(6923-22-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless crystals.
Odor - Mild, sweet.
Commercial Forms • Reddish-brown semisolid, water-soluble concentrate, mixture,
granules.
Use - Pesticide.
Other Names - Azodrin; Bilobran; (E)-dimethyl l-methyl-3-(methylamino)-3-oxo-l-
propenyl phosphate; ENT 27129; Monocron; Nuvacron; Pillardrin; Plantdrin.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, syrup of Ipecac,
activated charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's
lactate, atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Monocrotophos Exposure:
Note: Monocrotophos is a cholinesterase inhibitor.
Acute exposure to monocrotophos may result in the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Hypotension (low blood pressure) may occur,
although hypertension (high blood pressure) is not uncommon. Chest pain may be
noted. Dyspnea (shortness of breath) may lead to respiratory collapse.
Giddiness is common.
V
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EFATG
CAS Registry Number: 6923-22-4
Page 2 of 3
MONOCROTOPHOS
Emergency Life-Support Procedures:
Acute exposure to monocrotophos may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to monocrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to monocrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 6923-22-4
Page 3 of 3
MONOCROTOPHOS
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of monocrotophos is unknown or suspected to be greater than 30
minutes, do not induce vomiting and proceed to Step 4. Ipecac should not
be administered to children under 6 months of age.
Warning: Ingestion of monocrotophos may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 7446-09-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFUR DIOXIDE
CAS Registry Number: 7446-09-5
Synonyms: Sulfur Oxide; Sulfurous Acid Anhydride; Sulfurous Anhydride;
Sulf urous Oxide; Sulphur Dioxide
Chemical Formula: SO2
Molecular Weight: 64.07
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 14°F, -10°C (*Merck 1976)
Specific Gravity (H2O=1): Liquid: 1.434 (*Weast 1979)
Vapor Pressure (mmHg): 2432 at 68°F (*Hawley 1977)
Melting Point: -98.9°F, -72.7°C (*Weast 1979)
Vapor Density (AIR=1): 2.26 (*General Electric Co. 1979, MSDS #50)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 17.7% at 0°C; 11.9% at 15°C; 8.5% at 25°C; 6.4% at
35°C ("Merck 1976)
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CAS Registry Number: 7446-09-5
Page 2 of 4
SULFUR DIOXIDE
SECTION II (continued)
Appearance and Odor: Colorless liquid or gas with a strong suffocating
odor (*Merck 1976).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 5 ppm (13 mg/m3) (NIOSH/OSHA 1978, p. 168)
ACGIH TLV: TWA 2 ppm (5 mg/ms); STEL 5 ppm (10 mg/ms) (ACGIH 1985, p. 30)
IDLH: 100 ppm (*NIOSH/OSHA 1981)
Other Limits Recommended: NIOSH: 0.5 ppm, 10-hour TWA (NIOSH 1987,
p. 212). EEGL 10.0 ppm (60 minutes) (NRC 1984b, pp. 95-102).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): It may cause death or
permanent injury after very short exposure to small quantities (*Sax 1975).
1,000 ppm causes death in from 10 minutes to several hours by respiratory
depression (*Thienes 1972). It is an eye and respiratory tract irritant
(*Grant 1974; *Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Persons with asthma,
subnormal pulmonary functions or cardiovascular disease are at a greater
risk (*OSHA 1977 Public hearing on occupational standard for sulfur dioxide
(PB83-182485); *Encyc Occupat Health and Safety 1971).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable (Weiss 1980, p. 841). Extinguish
fires with dry chemical, carbon dioxide, water spray, fog or foam (*DOT
1984).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing. Move container from fire area. Stay away
from ends of tanks. Cool containers that are exposed to flames with water
from the side until well after the fire is out. Isolate area until gas has
dispersed. Keep unnecessary people away (*DOT 1984).
Unusual Fire and Explosion Hazards: Containers may explode in heat of
fire (*DOT 1984), or they may rupture and release irritating toxic sulfur
dioxide (*CHRIS 1978). Sulfur dioxide has explosive properties when it
comes in contact with sodium hydride; potassium chlorate at elevated
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CAS Registry Number: 7446-09-5
Page 3 of 4
SULFUR DIOXIDE
SECTION IV (continued)
temperatures; ethanol; ether; zinc ethylsulfurinate at very cool
temperatures (-15°C); fluorine; chlorine trifluoride and chlorates
(*Bretherick 1979; *NFPA 1978). It will react with water or steam to
produce toxic and corrosive fumes (*Sax 1975).
NFPA Flammability Rating: 0
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Ammonia (*General Electric Co.
1979, MSDS #50); monocesium or monopotassium acetylide; dicesium monoxide;
iron (II) oxide; tin oxide; lead (IV) oxide; chromium; manganese; molten
sodium (*Bretherick 1979); powder aluminum and rubidium (*NFPA 1978).
Sulfur dioxide has explosive properties when it comes in contact with
sodium hydride; potassium chlorate at elevated temperatures; ethanol;
ether; zinc ethylsulf urinate at very cool temperatures (-15C); fluorine;
chlorine trifluoride and chlorates (*Bretherick 1979; *NFPA 1978).
It will react with water or steam to produce toxic and corrosive fumes
(*Sax 1975).
Hazardous Decomposition or Byproducts: When the liquid is heated it may
release irritating, toxic sulfur dioxide gas (*CHRIS 1978).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 891)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used in preserving fruits and vegetables (*Merck 1976). Chemical
intermediate for various organic syntheses (*SRI); antioxidant (*Patty
1963); bleaching agent; inhibitor for various reactions in manufacturing
process; solvent and refrigerant (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away. Stay upwind and out of low areas. In case
of spills or leaks, stop leak if you can do so without risk. Use water
spray to reduce vapor but do not put water on the spill (*DOT 1984).
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CAS Registry Number: 7446-09-5
Page 4 of 4
SULFUR DIOXIDE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7446-09-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
SULFUR DIOXIDE
(7446-09-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas or liquid under pressure.
Odor - Strong, suffocating.
Commercial Form • Liquefied gas in 2- to 300-lb pressure cylinders, ton drums
on multi-unit cars, 40,000-lb tank cars.
Uses - Fruit and vegetable preservative, antioxidant, bleaching agent, solvent,
refrigerant, organic synthesis, inhibitor for various reactions in
manufacturing.
Caution: Explosion potential is high upon contact with a variety of chemicals.
To ensure safety, exit from areas where sulfur dioxide may be present before
instituting emergency life-support procedures.
Other Names - Sulfur oxide, sulfurous acid anhydride, sulfurous anhydride,
sulfurous oxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate.
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EFATG
CAS Registry Number: 7446-09-5
Page 2 of 3
SULFUR DIOXIDE
Signs and Symptoms of Acute Sulfur Dioxide Exposure:
Note: Persons with asthma, subnormal pulmonary function, or cardiovascular
disease are at greater risk.
Sulfur dioxide may irritate the eyes and respiratory tract. Signs and symptoms
of acute exposure to sulfur dioxide may be severe and include coughing,
choking, dyspnea (shortness of breath), sneezing, wheezing, and chest
discomfort. Upper airway edema (swelling) or obstruction, bronchoconstriction,
pneumonia, pulmonary edema, and respiratory paralysis may occur. Fatigue may
be noted.
Gastrointestinal effects may include nausea, vomiting, and abdominal pain.
Cyanosis (blue tint to skin and mucous membranes) may be noted following
exposure to sulfur dioxide.
Emergency Life-Support Procedures:
Acute exposure to sulfur dioxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to sulfur dioxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to sulfur dioxide.
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EFATG
CAS Registry Number: 7446-09-5
Page 3 of 3
SULFUR DIOXIDE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
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CAS Registry Number: 7446-11-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFUR TRIOXIDE
CAS Registry Number: 7446-11-9
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 677): Sulfan; Sulfuric
Anhydride; Sulfuric Oxide
Chemical Formula: SO3
Molecular Weight: 80.06
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(guinea pig) 0.03 mg/liter/6 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 113°F, 45°C (all forms) (Hawley 1981, p. 983)
Specific Gravity (H2O=1): Alpha form: 1.97 at 30°C; Gamma form (liquid):
1.920 at 20°C/4°C (Weast 1979, pp. B-132 - B-133)
Vapor Pressure (mmHg): Alpha form: 73 at 25°C; Beta form: 344 at 25°C;
Gamma form: 433 at 25°C (Merck 1983, p. 1289)
Melting Point: Alpha form: 144°F, 62°C; Beta form: 90.5°F, 32.5°C;
Gamma form: 62.2°F, 16.8°C (Hawley 1981, p. 983)
Vapor Density (AIR=1): 2.76 (Sax 1984, p. 2492)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (Weast 1978, p. B172)
Appearance and Odor: Alpha form and Beta form: asbestos-like needles;
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CAS Registry Number: 7446-11-9
Page 2 of 4
SULFUR TRIOXIDE
SECTION II (continued)
Gamma form: ice-like mass or liquid (Merck 1983, p. 1289)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2492)
Skin: Not Found
Ingestion: Yes (DOT 1984, Guide 39)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic (Hawley 1981, p. 983). It is an irritant and corrosive to mucous
membranes (Merck 1983, p. 1289). Poisonous if inhaled or swallowed.
Contact causes severe burns to skin and eyes (DOT 1984, Guide 39).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not get water inside container. Small fires:
dry chemical or carbon dioxide. Large fires: flood fire area with water
from a distance. Do not get solid stream of water on spilled material.
Move container from fire area if you can do so without risk. Spray cooling
water on containers that are exposed to flames until well after fire is out
(DOT 1984, Guide 39).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 39).
Unusual Fire and Explosion Hazards: Fire risk in contact with organic
materials. An explosive increase in vapor pressure occurs when the alpha
form melts (Hawley 1981, p, 983). Combines with water with explosive
violence, forming sulfuric acid (Merck 1983, p. 1289). May ignite other
combustible materials (wood, paper, oil, etc.). Flammable poisonous gases
may accumulate in tanks and hopper cars. Runoff to sewer may create fire
or explosion hazard (DOT 1984, Guide 39).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 7446-11-9
Page 3 of 4
SULFUR TRIOXIDE
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: On exposure to air, it absorbs moisture and
emits dense white fumes (Merck 1983, p. 1289).
Incompatibility (Materials to Avoid): Water and organic materials (Hawley
1981, p. 983)
Hazardous Decomposition or Byproducts: Forms sulfuric acid on contact
with water (Merck 1983, p. 1289).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used in the sulfonation of organic compounds and in solar
energy collectors (Hawley 1981, p. 983). It is an intermediate in sulfuric
acid manufacture and in the manufacture of explosives (Merck 1983, p.
1289).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). Do not get water inside
container; stop leak if you can do so without risk. Do not touch spilled
material. Use water spray to reduce vapors but do not put water on leak or
spill area. Keep combustibles (wood, paper, oil, etc.) away from spilled
material. Dike spill for later disposal; do not apply water unless directed
to do so. Clean up only under supervision of an expert (DOT 1984, Guide 39).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This material may cause coughing,
choking, and severe discomfort at a concentration of 1 ppm (Merck 1983, p.
1289).
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CAS Registry Number: 7446-11-9
Page 4 of 4
SULFUR TRIOXIDE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. Speed in removing material from skin is of
extreme importance. In case of contact with material, immediately flush
skin or eyes with running water for at least 15 minutes. Keep victim quiet
and maintain normal body temperature (DOT 1984, Guide 39).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Gilman 1985
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CAS Registry Number: 7446-18-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THALLOUS SULFATE
CAS Registry Number: 7446-18-6
Synonyms: (NIOSH/RTECS 1983 SYNONYMS, VOLUME 3, p. 706)
Thallium(I)Sulfate(2:l); C.F.S.; CSF-Giftweizen; Dithallium Sulfate;
Dithallium(l+) Sulfate; M7-Giftkoerner; Rattengiftkonserve; Sulfuric Acid,
Dithallium(l+) Salt; Sulfuric Acid, Thallium(l+) Salt (1:2); Thallium Sulfate;
Thallium(I) Sulfate (Hayes 1982 Synonyms, p. 25) Bonide Antzix ant killer
(trademark); GTA ant bane(trademark); GTA bait(trademark); Magikil Jelly ant
bait(trademark); Martin's Rat-Stop(trademark); Liquid Mission Brand ant-roach
killer(trademark); Rex ant bait(trademark)
Chemical Formula: T12SO4
Molecular Weight: 504.80
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
20.3 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Thallium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes (Weast 1979, p. B-134)
Specific Gravity (H2O=1): 6.77 (Weast 1979, p. B-134)
Vapor Pressure (mmHg): Inappreciable (Hayes 1982, p. 25)
Melting Point: 1170°F, 632°C (Weast 1979, p. B-134)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 7446-18-6
Page 2 of 4
THALLOUS SULFATE
SECTION II (continued)
Solubility in Water: 4.87 g/100 ml at 20°C, 19.14 g/100 ml at 100°C
(Weast 1979, p. B-134)
Appearance and Odor: White rhomboid prisms to a colorless dense powder;
odorless (Hayes 1982, p. 25; Merck 1983, p. 1325; Hawley 1981, p. 1013)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Thallium Soluble Compounds) TWA 0.1 mg/ms, as thallium (skin)
(OSHA 1984, p. 663)
ACGIH TLV: (Thallium Soluble Compounds) TWA 0.1 mg/ms, as thallium (skin)
(ACGIH 1985, p. 31)
IDLH: (Thallium Compounds, Soluble) 20 mg/m8 (NIOSH/OSHA 1978,
p. 178)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2557)
Health Hazards (Acute, Delayed, and Chronic): Rated as extremely toxic.
The probable oral lethal dose in humans is 5 to 50 mg/kg, or between 7
drops and 1 teaspoon for a 150-pound person (Gosselin 1984, p. 11-139).
The mean lethal dose in an adult is probably about 1 gm of thallium sulfate
(Gosselin 1984, p. Ill 380). Chronic exposure causes hair loss starting 10
days after exposure and complete baldness in about a month (Clayton and
Clayton 1981-82, p. 1922).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific - Thallium Salts, n.o.s.) If
material is involved in fire, extinguish fire using agent suitable for type
of surrounding fire (material itself does not burn). Use water in flooding
quantities as fog. Use foam, carbon dioxide or dry chemical (Student 1981,
p. 497). For small fires use dry chemical, carbon dioxide, water spray, or
foam. For large fires use water spray, fog, or foam. Move container from
fire area if you can do so without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific -- Thallium Salts,
n.o.s.) For personnel protection avoid breathing dusts, and fumes from
burning material. Keep upwind. Avoid bodily contact with the material.
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CAS Registry Number: 7446-18-6
Page 3 of 4
THALLOUS SULFATE
SECTION IV (continued)
Wear boots, protective gloves, and goggles. Do not handle broken packages
without protective equipment. Wash away any material which may have
contacted the body with copious amounts of water or soap and water. Wear
self-contained breathing apparatus when fighting fires involving this
material. If contact with the material is anticipated, wear full
protective clothing (Student 1981, p. 497). Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas
(DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of thallium and sulfur oxide (Sax 1984, p. 2557).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of thallium and sulfur oxides (Sax 1984, p. 2557).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used as a rat poison, as ant bait and as a reagent in analytical chemistry
(Merck 1983, p. 1325). Also used for analysis (testing for iodine in the
presence of chlorine); ozonometry; rodenticide; and pesticide (Hawley 1981,
p. 1013). Not registered as a pesticide in the U.S. (USEPA/Pesticide
Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Thallium Salts, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas (DOT 1984, Guide 53).
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CAS Registry Number: 7446-18-6
Page 4 of 4
THALLOUS SULFATE
SECTION VIII » PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death due to shock. Dominant
effects include severe abdominal pain, vomiting and diarrhea. Blood in
vomitus and stools are often seen. In severe cases, tremors, delirium,
convulsions, paralysis, coma and even death may occur (Gosselin 1984, p.
III-381).
Emergency and First Aid Procedures: (Non-Specific — Thallium Salts,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
NFPA 1984
Weiss 1980
CHRIS 1978
Arena 1979
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Doull 1980
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CAS Registry Number: 7487-94-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MERCURIC CHLORIDE
CAS Registry Number: 7487-94-7
Synonyms: Mercury (II) Chloride; Abavit B; Bichloride of Mercury; Calochlor;
Corrosive Mercury Chloride; Corrosive Sublimate; Dichloromercury; Fungchex; MC;
Mercuric Bichloride; Mercury Bichloride; Mercury Dichloride; Mercury
Perchloride; NCI-C60173; Perchloride of Mercury; Sublimate; Sulem; TL 898;
Mercuric Chloride, Solid (DOT); Mercury Chloride
Chemical Formula: HgCl2
Molecular Weight: 271.52
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
1 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 576°F, 302°C (*Weast 1979)
Specific Gravity (H2O=1): 5.44 at 25°C (*Weast 1979)
Vapor Pressure (mmHg): 1 at 136.2°C (*Sax 1979)
Melting Point: 529°F, 276°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 6.9 g/100 ml at 20°C (*Weast 1979)
Appearance and Odor: White crystals or powder (*Weast 1979); odorless
(Weiss 1980, p. 581)
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CAS Registry Number: 7487-94-7
Page 2 of 4
MERCURIC CHLORIDE
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: (Mercury and inorganic compounds) Ceiling 0.1 mg/m3, as mercury
(NIOSH 1987, p. 152)
ACGIH TLV: (Mercury, Aryl and inorganic compounds) TWA 0.10 mg/m3, as
mercury (skin) (ACGIH 1986-87, p. 22)
IDLH: Not Found
Other Limits Recommended: (Mercury and inorganic compounds) NIOSH:
0.05 mg/m3, 10-hour TWA, as mercury (NIOSH 1987, p. 152) IDLH for mercury
and inorganic compounds 28 mg/m3 (NIOSH 1987, p. 152)
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 581)
Skin: Yes (*Gosselin 1976)
Ingestion: Yes (*Browning 1969)
Health Hazards (Acute, Delayed, and Chronic): It is classified as
extremely toxic. All forms of mercury are poisonous if absorbed. Probable
oral lethal dose is 5-50 mg/kg; between 7 drops and 1 teaspoonful for a 150
Ib. person. Mercuric chloride is one of the most toxic salts of mercury
(*Gosselin 1976). Material attacks the gastrointestinal tract and renal
systems (*Friberg 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Some of these materials may burn but none of them
ignite readily. Extinguish with water spray, fog, foam, dry chemical or
carbon dioxide (*DOT 1984).
Special Fire Fighting Procedures: Move container from fire area. Wear
self-contained breathing apparatus and full body protective clothing (*DOT
1984).
Unusual Fire and Explosion Hazards: Material may explode on heating, with
friction, or contact with alkali metals, sulfides, acetylene, ammonia, and
oxalic acid (*Rumack 1975 to Present).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 7487-94-7
Page 3 of 4
MERCURIC CHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 581)
Conditions to Avoid: Mercuric chloride may explode with friction or
application of heat. Mixtures of mercuric chloride and sodium or
potassium are shock sensitive and will explode on impact (*NFPA 1978).
Avoid contact with acids or acid fumes (*Sax 1975).
Incompatibility (Materials to Avoid): Formates, sulfites, hypophosphites,
phosphates, sulfides, albumin, gelatin, alkalies, alkaloid salts, ammonia,
lime water, antimony, arsenic, bromides, borax, carbonates, reduced iron,
copper, iron, lead, silver salts, infusions of cinchona, columbo, oak bark
or senna, and tannic acid (*Merck 1983).
Hazardous Decomposition or Byproducts: Upon decomposition highly toxic
chloride and mercury fumes are emitted (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Preserving wood and anatomical specimens; embalming; browning and etching
steel and iron (*Merck 1983); catalyst for organic synthesis; disinfectant;
antiseptic; tanning; textile printing aid; manufacture of dyes;
agricultural chemicals and dry batteries; Pharmaceuticals; and photographic
chemicals (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
After spill keep unnecessary people away and stay upwind. If water
pollution occurs, notify appropriate authorities. Do not touch spilled
material; stop leak if you can do so without risk. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (*DOT
1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
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CAS Registry Number: 7487-94-7
Page 4 of 4
MERCURIC CHLORIDE
SECTION VIII (continued)
demand supplied air respirator with escape SC6A and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7487-94-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
MERCURIC CHLORIDE
(7487-94-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless crystals or white powder.
Odor - None.
Commercial Forms - Crystals, granules, wettable powder or dusts in 100-pound
drums.
Uses - Preserving wood and anatomical specimens; embalming; disinfectant;
browning and etching steel and iron; tanning; textile printing aid; catalyst
for organic synthesis; manufacture of dyes, agricultural chemicals, dry
batteries, Pharmaceuticals, and photographic chemicals.
Materials to Avoid - Reducing agents.
Caution: Avoid sources of heat including fire. Mercuric chloride may liberate
irritating or poisonous gases when heated to decomposition.
Other Names - Calochlor, corrosive sublimate, dichloromercury, Fungchex,
mercury bichloride, mercury perchloride, Sublimate, Sulem.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, penicillamine, dimercaprol (BAL).
-------
EFATG
CAS Registry Number: 7487-94-7
Page 2 of 3
MERCURIC CHLORIDE
Signs and Symptoms of Acute Mercuric Chloride Exposure:
Signs and symptoms of acute exposure to mercuric chloride may be severe and
include increased salivation, foul breath, inflammation and ulceration of the
mucous membranes, abdominal pain, and bloody diarrhea. Dermal exposure may
result in dermatitis (red, inflamed skin) and burns. Oliguria (scanty
urination), anuria (suppression of urine formation), and acute renal failure
may be noted. Weak pulse, seizures, psychic disturbances, circulatory
collapse, chest pain, and dyspnea (shortness of breath) may be observed.
Emergency Life-Support Procedures:
Acute exposure to mercuric chloride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to mercuric chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to mercuric chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
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EFATG
CAS Registry Number: 7487-94-7
Page 3 of 3
MERCURIC CHLORIDE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas for 15 minutes with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 7550-45-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TITANIUM TETRACHLORIDE
CAS Registry Number: 7550-45-0
Synonyms: Tetrachlorotitanium; Titanic Chloride; Titanium Chloride, (T-4)-;
Titanium Chloride
Chemical Formula: TiCl4
Molecular Weight: 189.73
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.1 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 277.5°F, 136.4°C (*Merck 1976)
Specific Gravity (H2O=1): 1.726 (*Merck 1976)
Vapor Pressure (mmHg): 10 at 21.3°C (Encyc Occupat Health and Safety
1983, p. 2180)
Melting Point: -11.4°F, -24.1°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in cold water (*Merck 1976)
Appearance and Odor: A colorless (*Merck 1976) or light yellow (*Weast
1979) liquid with penetrating acid odor (*Merck 1976)
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CAS Registry Number: 7550-45-0
Page 2 of 4
TITANIUM TETRACHLORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): This compound is a highly
corrosive, acute irritant to the skin, eyes, mucous membranes and the
respiratory tract. It is capable of causing death or permanent injury due
to exposures encountered in normal use (*Sax 1979). Even short contact may
lead to eye inflammation which may result in corneal opacities (Encyc
Occupat Health and Safety 1983, p. 2180).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable (Weiss 1980, p. 869). For small
fires, use dry chemical or carbon dioxide. For large fires, flood fire
area with water from a distance. Do not get solid streams of water on
spilled material. Move container from fire area if this can be done
without risk. Cool containers exposed to flames with water until well
after fire is out (*DOT 1984).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Material will react with water to
produce hydrochloric acid (*Thienes 1972). It may ignite other combustible
materials (e.g., wood, oil, etc.). Flammable, poisonous gases may
accumulate in tanks and hopper cars. Runoff to sewer may create fire or
explosion hazard (*DOT 1984).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 869); in concentrated
aqueous solutions (*Hawley 1977)
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CAS Registry Number: 7550-45-0
Page 3 of 4
TITANIUM TETRACHLORIDE
SECTION V (continued)
Conditions to Avoid: Avoid contact with moisture; the chemical
absorbs moisture from air and evolves dense white fumes (Merck 1983, p.
1357).
Incompatibility (Materials to Avoid): Water, moist air (Weiss 1980, p.
869)
Hazardous Decomposition or Byproducts: Reacts strongly with water to
release hydrochloric acid and heat (Thienes 1972).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacture of titanium salts, mordant dye, and titanium
pigments (*Hawley 1977), and used as a chemical intermediate for titanium
metal, titanium dioxide, as an agent in smoke screens, polymerization
catalyst, and iridescent agent in glass and pearl manufacturing (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate closed spaces before entering (*DOT 1984). In case of emergency,
keep unnecessary people away and isolate hazard area. Stay upwind and keep
out of low areas. Workers should receive periodic medical exams at
least annually and those manifesting signs of persistent injury to
upper respiratory tract should be transferred to other work
(*Encyc Occupat Health and Safety 1971).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED*
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 7550-45-0
Page 4 of 4
TITANIUM TETRACHLORIDE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation symptoms include congestion
and irritation of upper respiratory tract (*Browning 1969), coughing,
burning of the throat, headache and weakness. Prolonged exposure to low
concentrations may cause cough and pneumonia (*Rumack 1975 to Present).
Ingestion causes mouth, throat and GI tract irritation, nausea, vomiting,
cramps and diarrhea (Weiss 1980, p. 869). Corneal damage has been observed
in individuals exposed to fumes (*Grant 1974).
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site. Speed in removing material from skin is of extreme
importance. In case of contact, immediately flush skin or eyes with
running water for at least 15 minutes. Keep victim quiet and maintain
normal body temperature (*DOT 1984). If skin is exposed, however, wipe off
with dry cloth before applying water (*Rumack 1975 to Present).
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CAS Registry Number: 7580-67-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - LITHIUM HYDRIDE
CAS Registry Number: 7580-67-8
Synonyms: Lithium Monohydride; Lithium Hydride (LiH)
Chemical Formula: LiH
Molecular Weight: 7.95
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(rat) 0.022 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 0.76-0.77 (*Merck 1983)
Vapor Pressure (mmHg): 0 at 20°C (*NIOSH/OSHA 1981)
Melting Point: 1256°F, 680°C (*Merck 1983) 1267°F, 686°C (*NIOSH/OSHA
1978)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Merck 1983, p. 793)
Appearance and Odor: Pure lithium hydride is a white or translucent
crystalline mass or powder (*Hawley 1981). However, the commercial product
is usually gray (*Merck 1983). Lithium hydride is odorless (*CHRIS 1978).
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CAS Registry Number: 7580-67-8
Page 2 of 4
LITHIUM HYDRIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.025 mg/ms (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.025 mg/ms (*ACGIH 1984)
IDLH: 55 mg/m3 (NIOSH 1987, p. 148)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*Grant 1974; "Clayton and Clayton
1981-82)
Health Hazards (Acute, Delayed, and Chronic): This material is relatively
toxic to people. It is more likely to cause irritation of skin and mucous
membrane tissues rather than death. Its effects are primarily acute. A
massive exposure to the eyes and by inhalation may be lethal (*DOT 1984;
*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Those experiencing
any ailment of the upper respiratory tract (e.g., bronchitis or pneumonia)
are at a greater risk (*Rumack 1975 to Present).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Flammable solid (*NIOSH/RTECS 1985)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not use water, carbon dioxide, dry chemical, or
halogenated extinguishing agents such as carbon tetrachloride (*NFPA 1978).
Use dry graphite; or ground dolomite-based dry chemical extinguishers such
as "Lith-X" (*NFPA 1978, *Clayton and Clayton 1981-2). Fires may be
smothered by inverting a can over them (*NFPA 1984).
Special Fire Fighting Procedures: Wear protective goggles or face shield,
rubberized gloves, flame-proof outer clothing, respirator, and high boots
or shoes (*CHRIS 1978). Large fires: withdraw from area and let fire
burn, as lithium hydride may continue to re-ignite (*DOT 1984). A fire,
once started, cannot be extinguished by ordinary methods (*Clayton and
Clayton 1981-82).
Unusual Fire and Explosion Hazards: In a fire, irritating alkali fumes
may form (*CHRIS 1978). Lithium hydride can form airborne dust clouds
which may explode on contact with flame, heat, or oxidizing materials
(*NFPA 1978). Additionally, spontaneous ignition occurs when nitrous oxide
and lithium hydride are mixed. Lithium hydride also forms explosive
mixtures with liquid oxygen (*NFPA 1978).
NFPA Flammability Rating: 4
-------
CAS Registry Number: 7580-67-8
Page 3 of 4
LITHIUM HYDRIDE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (NFPA 1984, p. 49-59)
Stable:
Conditions to Avoid: Lithium hydride may ignite spontaneously in air
and should be maintained and handled out of contact with air and
moisture (*Clayton and Clayton 1981-82). Any contact with nitrous
oxide; airborne powders may ignite upon reaching moisture (*NFPA 1978).
Incompatibility (Materials to Avoid): Incompatible with air and moisture
(*Clayton and Clayton 1981-82), nitrous oxide, strong oxidizers, and liquid
oxygen (*NFPA 1978).
Hazardous Decomposition or Byproducts: Contact with heat, moisture or
acid causes exothermic reaction and evolution of hydrogen as well as
lithium hydroxide (*Clayton and Clayton 1981-82).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Lithium hydride is a reducing agent used for condensing ketones and acetic
esters. Used as a desiccant in hydrogen generators (*Merck 1983).
Preparation of double hydrides used in nuclear shielding materials (*Hawley
1981). Used in the manufacture of electronic tubes, ceramics, and chemical
synthesis (*Doull 1980).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Isolate hazard area and deny entry. Stay upwind; keep out of low areas.
In the event of a spill or leak, shut off ignition sources; no flares,
smoking or other sources of flame. Do not touch spilled materials. Do not
allow material to contact water. Shovel up small spills with noncombustible
absorbent material. Confine large spills with dikes, sheets, or tarps to
stop spreading (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 7580-67-8
Page 4 of 4
LITHIUM HYDRIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Butyl/Neoprene GOOD/LIMITED**
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7580-67-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
LITHIUM HYDRIDE
(7580-67-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White, translucent, crystalline mass or powder (darkens on
exposure to light).
Odor - None.
Commercial Forms - 93 to 95% pure light bluish-gray crystalline mass or a white
or gray powder contained in cans, cases, or drums.
Uses - Desiccant, chemical syntheses, reducing agent, hydrogen generators,
nuclear shielding materials, manufacture of electronic tubes and ceramics.
Materials to Avoid - Oxidizers, oxygen, and water (except for use in emergency
life support).
Caution: Explosion potential is high. Avoid any sources of extreme heat or
ignition including sparks or fire. Lithium hydride may spontaneously ignite on
contact with water or moist surfaces.
Other Names - Lithium monohydride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May be Required:
Compressed oxygen, forced-oxygen mask, water, milk, normal saline, D5W,
Ringer's lactate.
-------
EFATG
CAS Registry Number: 7580-67-8
Page 2 of 3
LITHIUM HYDRIDE
Signs and Symptoms of Acute Lithium Hydride Exposure:
Warning: Lithium hydride is an alkaline-corrosive agent. Contact with eyes
may result in severe damage to the cornea, conjunctiva, and blood vessels.
Caution is advised.
Acute exposure to lithium hydride may result in irritation and burning of the
skin, eyes, and mucous membranes. Increased salivation, dysphagia (difficulty
swallowing), abdominal pain, and spontaneous vomiting may occur. Stridor
(high-pitched, noisy respirations), dyspnea (shortness of breath), and
pulmonary edema are also common. Apathy and mental confusion may develop, with
progression to coma and death.
Emergency Life Support Procedures:
Acute exposure to lithium hydride may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to lithium hydride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to lithium hydride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
-------
EFATG
CAS Registry Number: 7580-67-8
Page 3 of 3
LITHIUM HYDRIDE
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 30 minutes.
5. Wash exposed skin areas for at least 15 minutes with water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
6. Transport to a health care facility.
-------
CAS Registry Number: 7631-89-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY « SODIUM ARSENATE
CAS Registry Number: 7631-89-2
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 439): Arsenic Acid, Sodium
Salt; Fatsco Ant Poison; Sodium Arsenate (DOT); Sodium Orthoarsenate; Sweeney's
Ant-Go
Chemical Formula: AsH3O4 xNa
Molecular Weight:
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rabbit) 12.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 1000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 7631-89-2
Page 2 of 4
SODIUM ARSENATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/ms, as arsenic (NIOSH 1987
P. 54)
ACGIH TLV: (Arsenic and soluble compounds) TWA 0.2 mg/ms, as arsenic
(ACGIH 1986-87, p. 10)
IDLH: Not Found
Other Limits Recommended: NIOSH: 0.002 mg/ms, IS-minute ceiling (NIOSH
1987, p. 54); NIOSH occupational carcinogen (NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 319)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific -- Arsenic)
High mortality rate due to acute poisoning usually within 48 hours
(Gosselin 1984, p. 111-42).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray or foam. Large fires: water spray, fog or foam. Move container
from fire area if you can do it without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing. If water pollution occurs, notify appropriate
authorities (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of arsenic (Sax 1984, p. 319).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
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CAS Registry Number: 7631-89-2
Page 3 of 4
SODIUM ARSENATE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of arsenic (Sax 1984, p. 319).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
Insecticide (Farm Chemicals Handbook 1984, p. C-207).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other non-combustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 7631-89-2
Page 4 of 4
SODIUM ARSENATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Arsenic) Death can
occur due to a severe decrease in blood pressure. Thickening of skin on
palms and soles following chronic low-level exposures. Symptoms usually
appear one-half to one hour after ingestion but may be delayed many hours.
These symptoms include: a feeling of constriction of throat, difficulty
swallowing, abdominal discomfort with pain, vomiting, watery diarrhea,
sweetish metallic taste, garlicky odor of breath and stools, and dizziness
with frontal headaches (Hayes 1982, p. 41; Gosselin 1984, p. 111-42).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
Weast 1979
Merck 1983
NIOSH/OSHA 1978
ACGIH 1984
Weiss 1980
Hawley 1981
Student 1981
DASE 1980
Clayton and Clayton 1981-82
Encyc Occupat Health and Safety 1983
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CAS Registry Number: 7637-07-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BORON TRIFLUORIDE
CAS Registry Number: 7637-07-2
Synonyms: ANCA 1040; Borane, Trifluoro-; Boron Fluoride; Boron Fluoride
(BF3); Trifluoroboron
Chemical Formula: BF3
Molecular Weight: 67.82
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.109 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -148°F, -99.9°C (*Weast 1979); -148.7°F, -100.4°C
(Merck 1983, p. 187)
Specific Gravity (H2O=1): Liquid: 1.6 (DASE 1980, p. 216)
Vapor Pressure (mmHg): Liquid: 760 at -100.7°C (Perry 1984, p. 3-47)
Melting Point: -196.1°F, -126.7°C (*Weast 1979)
Vapor Density (AIR=1): 2.4 (DASE 1980, p. 216)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 332 g/100 ml at 0°C (*Merck 1983); 106 g/100 ml
(Weast 1979, p. B-102); some hydrolysis occurs (Merck 1983, p. 187)
-------
CAS Registry Number: 7637-07-2
Page 2 of 4
BORON TRIFLUORIDE
SECTION II (continued)
Appearance and Odor: Colorless gas with a pungent, suffocating odor
(*Merck 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 1 ppm (3 mg/m3) (NIOSH/OSHA 1978, p. 50)
ACGIH TLV: Ceiling 1 ppm (3 mg/ms) (ACGIH 1983, p. 12)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 50)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 148)
Skin: Yes (DASE 1980, p. 216)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Highly toxic; may cause
death or permanent injury after very short exposure to small quantities
(*Sax 1975). Substance is irritating to the eyes, the skin, and the
respiratory tract (DASE 1980, p. 216).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (NIOSH/OSHA 1978, p. 50)
•LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam (DOT 1984, Guide 15).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and full protective clothing. Evacuate area endangered by gas.
Do not get water inside container. Move container from fire area if you
can do it without risk. Stay away from ends of tanks. Cool containers
that are exposed to flames with water from the side until well after fire
is out. Isolate area until gas has dispersed (DOT 1984, Guide 15).
Unusual Fire and Explosion Hazards: When heated to decomposition or upon
contact with water or steam, it will product toxic and corrosive fumes of
fluorine containing compounds (Sax 1984 p. 513). Decomposes upon heating
or on contact with moist air, forming toxic and corrosive fumes of boric
acid and hydrofluoric acid (DASE 1980, p. 216).
NFPA Flammability Rating: 0
-------
CAS Registry Number: 7637-07-2
Page 3 of 4
BORON TRIFLUORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*ACGIH 1980)
Stable:
Conditions to Avoid: It hydrolyzes in moist air to form boric acid,
hydrofluoric acid, and fluoboric acid (*ACGIH 1980).
Incompatibility (Materials to Avoid): Reacts with alkalis and fumes in
moist air, producing particulates which reduce visibility (NIOSH/OSHA 1978,
p. 50). Reacts with alkali metals, alkaline earth metals (except
magnesium), alkyl nitrates, and calcium oxide (Sax 1984, p. 513).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
will produce toxic and corrosive fumes of fluorine containing compounds
(Sax 1984, p. 513).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Catalyst in organic synthesis; production of diborane; instruments for
measuring neutron intensity; soldering fluxes; gas brazing (Hawley 1981, p.
146); protects molten magnesium and its alloys from oxidation; and a
fumigant (Merck 1983, p. 187). Not registered as a pesticide in the U.S.
(USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Stop leak if you can do it without risk. Use water spray to reduce vapor
but do not put water on leak or spill area. Small spills: flush area with
flooding amounts of water. Large spills: dike far ahead of spill for
later disposal. Do not get water inside container. Isolate area until
gas has dispersed (DOT 1984, Guide 15).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 7637-07-2
Page 4 of 4
BORON TRIFLUORIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
Neoprene ' GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7637-072
Page 1 of 3
Emergency First Aid Treatment Guide
for
BORON TRIFLUORIDE
(7637-07-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas.
Odor - Pungent, suffocating.
Commercial Form - Gas shipped in pressure cylinders or tank vehicles.
Uses - Catalyst in organic synthesis, manufacture of boranes, soldering flux,
gas brazing, oxidation protectant, fumigant, polymerizer of epoxy resins,
casting and heat treating in magnesium industry.
Materials to Avoid - Oxygen, water (except for use in emergency life support).
Caution: Avoid sources of heat including fire. Boron trifluoride will
liberate toxic and corrosive fumes when heated to decomposition and will
generate hydrofluoric, fluoboric, and boric acids upon contac' with water.
Other Names - ANCA 1040, trifluoroborane, trifluoroboron.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate.
-------
EFATG
CAS Registry Number: 7637-072
Page 2 of 3
BORON TRIFLUORIDE
Signs and Symptoms of Acute Boron Trifluoride Exposure:
Warning: Boron trifluoride is extremely corrosive. Caution is advised.
Acute inhalation exposure of boron trifluoride may result in sneezing,
hoarseness, choking, laryngitis, and respiratory tract irritation. Bleeding of
the nose and gums, ulceration of the nasal and oral mucosa, bronchitis,
pneumonia, dyspnea (shortness of breath), chest pain, and pulmonary edema may
also occur.
If the eyes have come in contact with boron trifluoride, irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure may
result in dermatitis (red, inflamed skin), severe burns, and pain.
Emergency Life-Support Procedures:
Acute exposure to boron trifluoride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to boron trifluoride
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to boron trifluoride.
-------
EFATG
CAS Registry Number: 7637-072
Page 3 of 3
BORON TRIFLUORIDE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support. Humidified oxygen is preferred.
2. IMMEDIATELY give the victims milk or water to dilute the hydrofluoric
acid: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to
12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Milk or water should be given only if victims are conscious and alert.
3. DO NOT induce vomiting.
4. Milk of Magnesia should be administered if victims are conscious and
alert. Use 2.5 mL (1/2 tsp) for children up to 1 year old, 5 mL (1 tsp)
for children 1 to 12 years old, and 10 mL (2 tsp) for adults. Do not
exceed 15 mL (3 tsp or 1 tbsp).
5. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
6. Activated charcoal is of no value.
7. Repeat the administration of water or milk to conscious and alert victims.
Use quantities listed above (see No. 2).
8. Transport to a health care facility.
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CAS Registry Number: 7647-01-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDROGEN CHLORIDE (gas only)
CAS Registry Number: 7647-01-0
Synonyms: Anhydrous Hydrochloric Acid; Chlorohydric Acid; Hydrochloric
Acid Gas; Hydrochloric Acid, Trimer; Hydrochloride; Hydrogen Chloride
Dimer; Muriatic Acid; Spirits of Salt
Chemical Formula: HC1
Molecular Weight: 36.46
SECTION I « REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: Constant boiling azeotrope with water 227°F, 109°C
containing 20.22% hydrogen chloride (Merck 1983, p. 692); -121°F, -85°C
(gas) (*Weast 1979)
Specific Gravity (H2O=1): 1.05 at 15°C/4°C for 10.17% weight/weight
solution (Merck 1983, p. 692)
Vapor Pressure (mmHg): Not Found
Melting Point: Freezing point -13.7°F, -25.4°C (39.17% weight/weight
solution) (Merck 1983, p. 692); -174.6°F, -114.8°C (gas) (*Weast 1979)
Vapor Density (AIR=1): 1.268 (*Merck 1983)
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CAS Registry Number: 7647-01-0
Page 2 of 4
HYDROGEN CHLORIDE (gas only)
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 82.3 g/100 mL at 32°F (gas) (*Weast 1979)
Appearance and Odor: Colorless gas or liquid (*Weast 1979). Irritating
pungent odor (*NFPA 1978). May be colored yellow by traces of iron,
chlorine, and organic matter (*Merck 1983).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Ceiling 5 ppm (7 mg/m3) (NIOSH/OSHA 1978, p. 110)
ACGIH TLV: Ceiling 5 ppm (7 mg/m3) (ACGIH 1986-87, p. 20)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 110)
Other Limits Recommended: EEGL 20.0 ppm (60 minutes) (NRC 1987, pp.
17-30). SPEGL 1.0 ppm (60 minutes) (NRC 1987, pp. 17-30).
Routes of Entry: Inhalation: Yes (*Merck 1983)
Skin: Yes (*Merck 1983)
Ingestion: Yes (*Merck 1983)
Health Hazards (Acute, Delayed, and Chronic): Gas concentrations of 50 to
100 ppm are tolerable for 1 hour. Concentrations of 1,000 to 2,000 ppm are
dangerous, even for brief exposures. More severe exposures will result in
serious respiratory distress and prolonged exposures will result in death.
Mists of hydrochloric acid are considered less harmful than anhydrous
hydrochloric acid, because droplets have no dehydrating action (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Individuals with
respiratory problems and digestive diseases may be adversely affected by
low level exposures to the gas or mist (*Encyc Occupat Health and Safety
1983).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not combustible (*NFPA 1978)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Normal fire fighting procedures may be used (*NFPA
1978). Do not get water inside containers. Move containers from fire
area. Keep containers that are exposed to the fire cool with water that is
sprayed from the side until well after the fire is out (*DOT 1984).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
and full protective clothing (*DOT 1984). Neutralize with chemically basic
substances such as soda ash or slaked lime (*NFPA 1978).
-------
CAS Registry Number: 7647-01-0
Page 3 of 4
HYDROGEN CHLORIDE (gas only)
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases. Containers may explode in heat of fire (*DOT 1984).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 513)
Conditions to Avoid: Avoid heat; at high temperatures it will
decompose into hydrogen and chlorine (*Encyc Occupat Health and Safety
1983).
Incompatibility (Materials to Avoid): Mercuric sulfate -- violent
reaction with gaseous hydrochloric acid at 250F. Sodium -- reacts
vigorously with gaseous hydrochloric acid. Acetic anhydride,
2-aminoethanol, ammonium hydroxide, chlorosulfonic acid, ethylene diamine,
ethyleneimine, oleum, propiolactone, sodium hydroxide, sulfuric acid, and
vinyl acetate -- increase in temperature and pressure when mixed with
hydrochloric acid. Calcium phosphide -- energetic reaction with
hydrochloric acid. Silver perchlorate and carbon tetrachloride — when
mixed in combination with hydrochloric acid forms a compound that detonates
at 105F (*NFPA 1978). Formaldehyde -- when mixed with hydrochloric acid
forms a human carcinogen (*NRC 1981).
Material reacts violently with bases and is corrosive with the generation
of heat. Reacts with base metals, forming combustible gas (hydrogen).
Reacts violently with strong oxidants forming toxic gas (chlorine) (DASE
,980, p. 541).
Hazardous Decomposition or Byproducts: At high temperatures, it
decomposes into hydrogen and chlorine (*Encyc Occupat Health and Safety
1983).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Major uses of hydrochloric acid include refining metal ore, lab reagent,
and removing scale from boilers (*Merck 1983). It is also a metal treating
agent; it is used in food processing, and to neutralize waste streams
(*Hawley 1981). It is used in the manufacture of fertilizers and dyes, in
electroplating, in the textile industry, and in the rubber industry (*Encyc
Occupat Safety and Health 1983).
-------
CAS Registry Number: 7647-01-0
Page 4 of 4
HYDROGEN CHLORIDE (gas only)
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away and stay upwind. Stay out of low areas.
Ventilate closed areas before entering them. Use water spray to
reduce vapor from leak. For small spills, flush area with flooding
amounts of water. For larger spills, dike far ahead of spill for
later disposal. Do not get water inside containers (*DOT 1984).
Spilled material can be neutralized with powdered limestone,
slaked lime, soda ash, or sodium bicarbonate (*CHRIS 1978).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Butyl/Neoprene GOOD/LIMITED
CPE ' GOOD/LIMITED
Chlorobutyl GOOD/LIMITED
Neoprene EXCELLENT/MANY
Nitrile GOOD/LIMITED
PVC POOR/MANY
Saranex GOOD/LIMITED
Teflon POOR/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
NOTES: Based on 100% HC1 liquid
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7647-01-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDROGEN CHLORIDE
(7647-01-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas; colorless to slightly yellow water solution.
Odor - Pungent, suffocating.
Commercial Forms - Gas in pressurized containers; aqueous liquid in glass
bottles, carboys, rubber-lined steel drums, rubber-lined tank cars.
Uses - Laboratory reagent, activator of petroleum wells, metal ore refining,
boiler scale removal agent, metal treating, food processing, waste stream
neutralizer, electroplating, fertilizers.
Other Names - Clorohydric acid, hydrochloric acid, muriatic acid.
Personal Protective Equipment: Se~ Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Hydrogen Chloride Exposure:
Warning: Hydrogen chloride is extremely corrosive. Caution is advised.
Signs and symptoms of acute ingestion of hydrogen chloride may be severe and
include salivation, intense thirst, difficulty in swallowing, chills, pain, and
shock. Oral, esophageal, and stomach burns are common. Vomitus generally has
a coffee-ground appearance. The potential for circulatory collapse is high
following ingestion of hydrogen chloride.
-------
EFATG
CAS Registry Number: 7647-01-0
Page 2 of 3
HYDROGEN CHLORIDE
Acute inhalation exposure of hydrogen chloride may result in sneezing,
hoarseness, choking, laryngitis, and respiratory tract irritation. Bleeding of
nose and gums, ulceration of the nasal and oral mucosa, bronchitis, pneumonia,
dyspnea (shortness of breath), chest pain, and pulmonary edema may also occur.
If the eyes have come in contact with hydrogen chloride, irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure may
result in dermatitis (red, inflamed skin), severe burns, and pain.
Emergency Life-Support Procedures:
Acute exposure to hydrogen chloride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrogen chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrogen chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
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EFATG
CAS Registry Number: 7647-01-0
Page 3 of 3
HYDROGEN CHLORIDE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Rinse mouth with large amounts of water. Victims should not attempt to
swallow this water.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
-------
CAS Registry Number: 7664-39-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDROGEN FLUORIDE
CAS Registry Number: 7664-39-3
Synonyms: Hydrofluoric Acid; Anhydrous Hydrofluoric Acid; Antisal 2B;
Fluorhydric Acid; Hydrofluoric Acid Gas; Hydrofluoric Acid, Anhydrous (DOT)
Chemical Formula: HF
Molecular Weight: 20.01
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.28 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 67.1°F, 19.51°C (*Merck 1976)
Specific Gravity (H2O=1): 0.991 at 19.5°C (Weast 1983, p. B-97)
Vapor Pressure (mmHg): 400 at 2.5°C (*Sax 1975)
Melting Point: -118.4°F, -83.55°C (*Merck 1976)
Vapor Density (AIR=1): 0.7 (Weiss 1980, p. 515)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (*Merck 1976)
Appearance and Odor: Colorless, fuming liquid or gas with a strong,
irritating odor (NIOSH/OSHA 1978, p. 112).
-------
CAS Registry Number: 7664-39-3
Page 2 of 4
HYDROGEN FLUORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 3 ppm (NIOSH/OSHA 1978, p. 112)
ACGIH TLV: Ceiling TWA 3 ppm (2.5 mg/m3); STEL 6 ppm (ACGIH 1987, p.21)
IDLH: 30 ppm (NIOSH 1987, p. 138)
Other Limits Recommended: NIOSH: 3 ppm 10-hour TWA, 6ppm 15-minute ceiling
(NIOSH 1987, p. 138)
Routes of Entry: Inhalation: Yes (*NRC 1981)
Skin: Yes (*Clayton and Clayton 1981-82)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Ingestion of an estimated
1.5 grams produced sudden death without gross pathological damage.
Repeated ingestion of small amounts resulted in moderately advanced
hardening of the bones (*Gosselin 1976). Contact of skin with anhydrous
liquid produces severe'burns (*Clayton and Clayton 1981-82). Inhalation of
anhydrous hydrogen fluoride or hydrogen fluoride mist or vapors can cause
severe respiratory tract irritation that may be fatal (*NRC 1981).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Flammable (Weiss 1980, p. 515)
Flammable Limits:
LEL: Non-Flammable (*Encyc Occupat Health and Safety 1976)
UEL: Non-Flammable (*Encyc Occupat Health and Safety 1976)
Extinguishing Methods: Use water on fires in which hydrofluoric acid is
involved (*NFPA 1978).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated, it emits highly
corrosive fumes of fluorides (*Sax 1975). Its corrosive action on metals
can result in formation of hydrogen in containers and piping to create fire
hazard (*Encyc Occupat Health and Safety 1971).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 515)
Conditions to Avoid: May generate flammable hydrogen gas in contact
with some metals (Weiss 1980, p. 515)
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CAS Registry Number: 7664-39-3
Page 3 of 4
HYDROGEN FLUORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Will attack glass, concrete, and
certain metals, especially those containing silica, such as cast iron.
Will attack natural rubber, leather, and many organic materials (Weiss
1980, p. 515).
Hazardous Decomposition or Byproducts: Toxic and irritating vapors are
generated when heated (Weiss 1980, p. 515).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Removing efflorescence from brick and stone, or sand particles from
metallic castings; working over too heavily weighted silks; cleaning cast
iron, copper, brass; polishing crystal glass; decomposition of cellulose;
enameling and galvanizing iron; increasing porosity of ceramics; in
fluorination processes, especially in the aluminum industry; manufacture of
fluorides; separating uranium isotopes; in making fluoride containing
plastics; in dye chemistry (*Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill or leak to disperse gas. If in gaseous form, stop
flow of gas. If source of leak is cylinder and leak cannot be stopped,
remove to safe place in open air and repair leak or allow cylinder to
empty. If in liquid form, allow to vaporize and disperse the gas
(*NIOSH/OSHA 1981).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Butyl/Neoprene POOR/LIMITED
CPE GOOD/LIMITED*
Neoprene POOR/LIMITED*
Nitrile POOR/LIMITED*
PE GOOD/LIMITED
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CAS Registry Number: 7664-39-3
Page 4 of 4
HYDROGEN FLUORIDE
SECTION VIII (continued)
PVC POOR/MANY
Saranex GOOD/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
NOTES: Based on 100% HF liquid
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7664-39-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDROGEN FLUORIDE
(7664-39-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas.
Odor - Strongly irritating.
Commercial Forms - 99.9% pure gas in cylinders or tank cars; 48, 52, and 70%
pure aqueous solutions.
Uses - Specialty chemical manufacture; metal, brick, and sand cleaning; iron
galvanizing; silk working; crystal or glass polishing; increasing ceramic
porosity; separating uranium isotopes; cellulose decomposition; dye chemistry;
petrochemical refining.
Materials to Avoid - Water (except for use in emergency life support).
Other Nam s - Anhydrous hydrofluoric acid, fluorohydric acid gas, hydrofluoric
acid.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, milk of Magnesia,
normal saline, D5W, Ringer's lactate, calcium gluconate.
-------
EFATG
CAS Registry Number: 7664-39-3
Page 2 of 3
HYDROGEN FLUORIDE
Signs and Symptoms of Acute Hydrogen Fluoride Exposure:
Warning: Hydrogen fluoride is highly corrosive. Effects may be delayed from
1 to 24 hours. Caution is advised.
Acute exposure to hydrogen fluoride will result in irritation, burns, ulcerous
lesions, and necrosis of the eyes, skin, and mucous membranes. Total
destruction of the eyes is possible. Other effects include nausea, vomiting,
diarrhea, pneumonitis (inflammation of the lungs), and circulatory collapse.
Emergency Life-Support Procedures:
Acute exposure to hydrogen fluoride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as hydrogen fluoride-resistant plastic
sheeting and disposable plastic bags to assist in preventing spread of
contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrogen fluoride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support. Humidified oxygen is preferred.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrogen fluoride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support. Humidified oxygen is preferred.
3. Remove contaminated clothing as soon as possible.
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EFATG
CAS Registry Number: 7664-39-3
Page 3 of 3
HYDROGEN FLUORIDE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support. Humidified oxygen is preferred.
2. IMMEDIATELY give the victims milk or water to dilute the hydrofluoric
acid: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to
12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Milk or water should be given only if victims are conscious and alert.
3. DO NOT induce vomiting.
4. Milk of Magnesia should be administered if victims are conscious and
alert. Use 2.5 mL (1/2 tsp) for children up to 1 year old, 5 mL (1 tsp)
for children 1 to 12 years old, and 10 mL (2 tsp) for adults. Do not
exceed 15 mL (3 tsp or 1 tbsp).
5. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
6. Activated charcoal is of no value.
7. Repeat the administration of water or milk to conscious and alert victims.
Use quantities listed above (see No. 2).
8. Transport to a health care facility.
-------
CAS Registry Number: 7664-41-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- AMMONIA
CAS Registry Number: 7664-41-7
Synonyms: AM-FOL; Ammonia Gas; Ammonia, Anhydrous; Nitro-Sil; R 717; Spirit
of Hartshorn; Liquid Ammonia
Chemical Formula: HSN
Molecular Weight: 17.03
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -28.03°F, -33.35°C (*Merck 1976)
Specific Gravity (H2O=1): Liquid 0.6818 at -33.35°C (Merck 1983, p. 74)
Vapor Pressure (mmHg): 400 at -45.4°C (*Weast 1983)
Melting Point: -107.9°F, -77.7°C (*Merck 1976)
Vapor Density (AIR=1): 0.6 (Weiss 1980, p. 73)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 31 g/100 g at 25°C (*Merck 1983)
Appearance and Odor: Colorless gas, liquid (*Weast 1979); sharp, cloying,
repellant odor (*Booth 1982)
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CAS Registry Number: 7664-41-7
Page 2 of 4
AMMONIA
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 50 ppm (35 mg/m3) (NIOSH 1987, p. 50)
ACGIH TLV: TWA 25 ppm (18 mg/m3); STEL 35 ppm (27 mg/ms) (*ACGIH 1983)
IDLH: 500 ppm (NIOSH/OSHA 1978, p. 44)
Other Limits Recommended: Short-term inhalation limits: 50 ppm for 5
minutes (*CHRIS 1978). NIOSH: 50 ppm (35 mg/m3) 5-minute ceiling (NIOSH
1987, p. 50). EEGL 100.0 ppm (60 minutes) (NRC 1987, pp. 7-16).
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 73)
Skin: Yes (Weiss 1980, p. 73)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Vapors cause irritation of
eyes and respiratory tract (*Gosselin 1976). Liquid will burn skin and
eyes ("CHRIS 1978). Poisonous; may be fatal if inhaled. Contact may cause
burns to skin and eyes. Contact with liquid may cause frostbite (DOT 1984,
Guide 15).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: 16% (*NFPA 1978)
UEL: 25% (*NFPA 1978)
Extinguishing Methods: Small fires: dry chemical or carbon dioxide.
Large fires: water spray, fog or foam. Apply water gently to the surface.
Do not get water inside container. Move container from fire area if you
can do it without risk. Stay away from ends of tanks. Cool containers
that are exposed to flames with water from the side until well after fire
is out. Isolate area until gas has dispersed (DOT 1984, Guide 15).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and full protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Mixing of ammonia with several
chemicals can cause severe fire hazards and/or explosions (*Bretherick
1979; *NFPA 1978; *Merck 1983). Ammonia in container may explode in heat
of fire (*DOT 1984).
NFPA Flammability Rating: 1
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 73)
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CAS Registry Number: 7664-41-7
Page 3 of 4
AMMONIA
SECTION V (continued)
Conditions to Avoid: Mixing with other chemicals and water
(*Bretherick 1979).
Incompatibility (Materials to Avoid): Incompatible with many materials
including silver and gold salts, halogens, alkali metals, nitrogen
trichloride, potassium chlorate, chromyl chloride, oxygen halides, acid
vapors, azides, ethylene oxide (*Bretherick 1979), picric acid
(*Environment Canada 1981), and many other chemicals (*NFPA 1978).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 73)
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Twenty-five percent used as a direct application fertilizer; intermediate
uses include 10% used to make urea fertilizer; 19% for ammonium nitrate
fertilizer; 18% for all other fertilizers; 4% for ammonium nitrate-based
commercial explosives; 7% for major fiber and plastic intermediates, and
14% for all other applications (*SRI). Also used as a bactericide (USEPA/
Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill or leak to disperse gas. If in gaseous form stop
flow of gas. If source of leak is a cylinder and leak cannot be stopped in
place, remove leaking cylinder to safe place in open air and repair leak or
allow cylinder to empty. If in liquid form allow to vaporize (*NIOSH/OSHA
1981). Keep unnecessary people away; isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Evacuate area endangered by gas (DOT 1984, Guide 15).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7664-41-7
Page 4 of 4
AMMONIA
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED*
Neoprene GOOD/LIMITED*
PVC GOOD/LIMITED*
Viton POOR/LIMITED*
Viton/Neoprcne POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7664-41-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
AMMONIA
(7664-41-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas.
Odor - Sharp, repelling.
Commercial Form - Compressed liquefied gas in steel cylinders, pressurized tank
cars, barges, pipelines.
Uses - Fertilizer, chemical intermediate, condensation catalyst, latex
preservative, bactericide, refrigerant, rocket fuel component, nitriding of
steel, explosives intermediate.
Caution: Ammonia in containers may explode in heat of fire. Water used to
dilute large ammonia spills must be added cautiously to avoid violent fuming.
Other Names - Anhydrous ammonia, liquid ammonia, ammonium hydroxide (ammonia
in water, CAS No. 1336-21-6).
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
-------
EFATG
CAS Registry Number: 7664-41-7
Page 2 of 3
AMMONIA
Signs and Symptoms of Acute Ammonia Exposure:
Warning: Ammonia is extremely corrosive to the skin, eyes, and mucous
membranes. Contact with the liquified gas may cause frostbite. Caution is
advised.
Inhalation of ammonia may cause irritation and burns of the respiratory tract,
laryngitis, dyspnea (shortness of breath), stridor (high-pitched respirations),
and chest pain. Pulmonary edema and pneumonia may also result from inhalation.
A pink frothy sputum, convulsions, and coma are often seen following exposure
to high concentrations. When ammonia is ingested, nausea and vomiting may
result; oral, esophageal, and stomach burns are common.
If ammonia has contacted the eyes, irritation, pain, conjunctivitis (red,
inflamed eyes), lacrimation (tearing), and corneal erosion may occur. Loss of
vision is possible. Dermal exposure may result in severe burns and pain.
Emergency Life-Support Procedures:
Acute exposure to ammonia may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to ammonia.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to ammonia.
-------
EFATG
CAS Registry Number: 7664-41-7
Page 3 of 3
AMMONIA
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
Warning: Do not attempt to neutralize with an acid wash; excessive
liberation of heat may result.
3. If eye exposure has occurred, eyes must IMMEDIATELY be flushed with
lukewarm water for at least 15 minutes.
4. Remove contaminated clothing as soon as possible.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induct vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal does not strongly bind ammonia, and therefore is of
little or no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
6. Transport to a health care facility.
-------
CAS Registry Number: 7664-93-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFURIC ACID
CAS Registry Number: 7664-93-9
Synonyms: Battery Acid; BOV; Chamber Acid; Dipping Acid; Fertilizer Acid;
Nordhausen Acid; Oil of Vitriol; Spirit of Sulfur; Sulphuric Acid; Vitriol
Brown Oil; Hydrogen Sulfate; Matting Acid; Spent Sulfuric Acid
Chemical Formula: H2SO4
Molecular Weight: 98.08 (*Merck 1983)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.018 mg/L (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 554°F, 290°C (*Merck 1983)
Specific Gravity (H2O=1): 1.841 (*Weast 1984)
Vapor Pressure (mmHg): 1 at 146°C (*Patty 1963)
Melting Point: 50.65°F, 10.36°C (*Weast 1984)
Vapor Density (AIR=1): 3.4 (*NIOSH/OSHA 1981)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Encyc Occupat Health and Safety 1983)
Appearance and Odor: Clear, colorless, oily liquid when pure; brownish
when impure (*Encyc Occupat Health and Safety 1983). Spent sulfuric acid
is a black oily liquid (*Student 1981); odorless (*Merck 1983); choking
odor when hot (*CHRIS 1978).
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CAS Registry Number: 7664-93-9
Page 2 of 4
SULFURIC ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 1 mg/m3 (*NIOSH/OSHA 1978)
ACGIH TLV: TWA 1 mg/ms (*ACGIH 1983)
IDLH: 80 mg/ms (*NIOSH/OSHA 1978)
Other Limits Recommended: NIOSH: 1 mg/m3 10-hour TWA (NIOSH 1987, p. 212).
EEGL 1 mg/m3 (60 minutes) (NRC 1984a, pp. 107-112).
Routes of Entry: Inhalation: Yes (*Merck 1983)
Skin: Yes (*Merck 1983)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): Corrosive to all body
tissues. Inhalation of vapor may cause serious lung damage. Contact with
eyes may result in total loss of vision. Skin contact may produce severe
necrosis (*Merck 1983). Fatal amount for adult: between 1 teaspoonful and
one-half ounce of the concentrated chemical. Even a few drops may be fatal
if the acid gains access to the trachea (*Arena 1974). Chronic exposure
may cause tracheobronchitis, stomatitis, conjunctivitis, and gastritis
(*ACGIH 1980). Gastric perforation and peritonitis may occur and may be
followed by circulatory collapse. Circulatory shock is often the immediate
cause of death (*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Those with chronic
respiratory, gastrointestinal, or nervous diseases and any eye and skin
diseases are at greater risk (*Encyc Occupat Health and Safety 1983).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable (Weiss 1980, p. 842). For small
fires use dry chemical or carbon dioxide. Use water on combustibles
burning in vicinity of this material (*NFPA 1978). For large fires flood
fire area with water from a distance. Do not get solid streams of water on
material. Move container from area if you can do so without risk (*DOT
1984).
Special Fire Fighting Procedures: Fight fire from safe distance or from
protected location. Use care as water applied directly to this acid
results in evolution of heat and causes spattering (*NFPA 1978). Cool
containers that are exposed to flames with streams of water until fire is
out. Wear positive pressure breathing apparatus and special protective
clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: It is highly reactive and capable of
igniting finely-divided combustible materials on contact (*NFPA 1978).
When heated, it emits highly toxic fumes (*Sax 1975).
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CAS Registry Number: 7664-93-9
Page 3 of 4
SULFURIC ACID
SECTION IV (continued)
NFPA Flammability Rating: 0
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 842)
Conditions to Avoid: Can undergo violent chemical change at elevated
temperatures and pressure. May react violently with water (*NFPA
1978). When heated, it emits highly toxic fumes (*Sax 1975).
Incompatibility (Materials to Avoid): Avoid heat; water (*NFPA 1978); and
organic materials (*Encyc Occupat Health and Safety 1983). Sulfuric acid
is explosive or incompatible with an enormous array of substances (*NFPA
1978; *Bretherick 1979; *Sax 1975; *ITI 1982).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 842)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used in the manufacture of dyestuffs; acids; parchment paper; glue;
petroleum purification (*Merck 1983); electroplating baths; non-ferrous
metallurgy; production of pigments, rayon, film, laboratory reagents,
etchant (*Hawley 1981), and herbicides (*Spencer 1982); dehydrating agen
for ethers, esters, and gases; refining mineral and vegetable oils; leather
industry (*Encyc Occupat Health and Safety 19&3); chemical intermediate for
fertilizers; agent in production of alcohols and explosives; iron and steel
pickling; and storage batteries (*ACGIH 1980).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Extremely hazardous to health; areas may be entered with extreme care. No
skin surface should be exposed (*NFPA 1978). Keep all sources of ignition
away from containers because explosive mixtures of hydrogen may be produced
during storage. Small spills: cover area with sodium bicarbonate or soda
ash/slaked lime. Shovel neutralized residues into containers for disposal,
or (if not available) cover area with sand or earth and shovel into
disposal containers (*Environment Canada 1984). Other neutralizing agents
are calcinated dolomite, calcivm oxide and hydroxide, sodium carbonate.
Place sulfuric acid absorbed in vermiculate in sealed containers
(*NIOSH/OSHA 1981). Keep unnecessary people away; isolate hazard area
and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Notify proper authorities in case of water
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CAS Registry Number: 7664-93-9
Page 4 of 4
SULFURIC ACID
SECTION VII (continued)
pollution. Do not touch spilled material. Use water spray to reduce
vapor; do not get water inside container. Dike for later disposal (*DOT
1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene GOOD/LIMITED
CPE EXCELLENT/MANY
Chlorobutyl GOOD/LIMITED
Neoprene GOOD/LIMITED
Nitrile POOR/LIMITED*
Nonwovwen PE POOR/MANY
PE GOOD/LIMITED
PVC POOR/MANY
Saranex EXCELLENT/MANY
Teflon POOR/LIMITED
Viton GOOD/LIMITED
Viton/Chlorobutyl GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7664-93-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
SULFURIC ACID
(7664-93-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Clear, colorless, oily liquid.
Odor - None.
Commercial Forms - Brownish when impure, 33 to 98% pure solutions.
Uses - Manufacture of dyestuffs, other acids, parchment paper, and glue;
purification of petroleum; medication; electroplating; metallurgy; pigments;
rayon; film; laboratory reagent and etchant; food additive; herbicide; gas
drying; refining mineral and vegetable oils; leather industry; carbonization of
wool fabrics; extraction of uranium from pitchblende; fertilizer; explosives;
storage batteries.
Materials to Avoid - Water (except for use in emergency life support).
Caution: Diluting sulfuric acid with water may result in a violent reaction.
Highly toxic fumes may be liberated when heated. Finely divided combustible
materials may ignite upon contact with sulfuric acid.
Other Names - Battery acid, Chamber acid, Fertilizer acid, Nordhausen acid.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
-------
EFATG
CAS Registry Number: 7664-93-9
Page 2 of 3
SULFURIC ACID
Signs and Symptoms of Acute Sulfuric Acid Exposure:
Caution: Sulfuric acid is extremely corrosive. Caution is advised.
Signs and symptoms of acute ingestion of sulfuric acid may be severe and
include salivation, intense thirst, difficulty in swallowing, pain, and shock.
Oral, esophageal, and stomach burns are common. Vomitus generally has a
coffee-ground appearance. The potential for circulatory collapse is high
following ingestion of sulfuric acid.
Acute inhalation exposure may result in sneezing, hoarseness, choking,
laryngitis, dyspnea (shortness of breath), respiratory tract irritation, and
chest pain. Bleeding of nose and gums, ulceration of the nasal and oral
mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur.
If the eyes have come in contact with sulfuric acid, irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure may
result in severe burns, pain, and dermatitis (red, inflamed skin).
Emergency Life-Support Procedures:
Acute exposure to sulfuric acid may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to sulfuric acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 7664-93-9
Page 3 of 3
SULFURIC ACID
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to sulfuric acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Instruct victims not to swallow
the water.
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
-------
CAS Registry Number: 7697-37-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NITRIC ACID
CAS Registry Number: 7697-37-2
Synonyms: Aqua Fortis; Azotic Acid; Engraver's Acid; Hydrogen Nitrate; Nital;
Nitric Acid (Red Fuming); Nitrous Fumes; Nitryl Hydroxide; Red Fuming Nitric
Acid; Nitric Acid (White Fuming)
Chemical Formula: HNOS
Molecular Weight: 63.01
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.17 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 181°F; 83°C (*Weast 1979); 248.9°F, 120.5°C for constant
boiling acid at 68% nitric acid (Merck 1983, p. 943)
Specific Gravity (H2O=1): 1.5027 at 25°C/4°C (*Weast 1979); 1.4134 at
20°C/4°C for 70% nitric acid (Merck 1983, p. 943)
Vapor Pressure (mmHg): 47.8 at 20°C (*Encyc Occupat Health and Safety
1983)
Melting Point: -44°F, -42°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in all proportions (*Weast 1979)
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CAS Registry Number: 7697-37-2
Page 2 of 4
NITRIC ACID
SECTION II (continued)
Appearance and Odor: Colorless or yellow liquid with acrid odor (*Merck
1983; *CHRIS 1975).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 2 ppm (5 mg/ms) (NIOSH 1987, p. 172)
ACGIH TLV: TWA 2 ppm (5 mg/ms); STEL 4 ppm (10 mg/ms) (*ACGIH 1984)
IDLH: 100 ppm (NIOSH/OSHA 1978, p. 138)
Other Limits Recommended: NIOSH: 2 ppm (5 mg/m3) 10-hour TWA (NIOSH 1987,
P. 172)
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 656)
Skin: Yes (Weiss 1980, p. 656)
Ingestion: Yes (Weiss 1980, p. 656)
Health Hazards (Acute, Delayed, and Chronic): This compound is a primary
irritant, and causes burns and ulceration of all tissues and membranes that
it contacts. This includes burns to the eyes and skin by contact, burns to
the mouth, throat, esophagus, and stomach by ingestion, and the entire
respiratory tract by inhalation. Circulatory collapse and shock is often
the immediate cause of death (*Gosselin 1984). The approximate minimum
lethal dose is 5 ml for a 150-lb person (*Arena 1979).
Medical Conditions Generally Aggravated by Exposure: Persons with skin,
eye or cardiopulmonary disorders are at a greater risk (*Encyc Occupat
Health and Safety 1983).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water spray (NFPA 1984, pp. 49-67). Small
fires: water, dry chemical, or soda ash. Large fires: flood fire area
with water. Move container from fire area if you can do so without risk.
Spray cooling water on containers that are exposed to flames until well
after fire is out. For massive fire in cargo area, use unmanned hose
holder or monitor nozzles; if this is impossible, withdraw from area and
let fire burn (DOT 1984, Guide 44).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 44).
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CAS Registry Number: 7697-37-2
Page 3 of 4
NITRIC ACID
SECTION IV (continued)
Unusual Fire and Explosion Hazards: May give off poisonous oxides of
nitrogen and acid fumes when heated in fires ("CHRIS 1978). May ignite
other combustible materials. Reactions with fuels may be violent. Runoff
to sewer may create fire or explosion hazard (*DOT 1984). Noncombustible
but dangerously reactive with many materials. Reacts explosively with
metallic powders, carbides, hydrogen sulfide, and turpentine. Increases
the flammability of combustible organic and readily oxidized materials.
Can cause ignition of some of these materials (NFPA 1984, p. 49-67).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Moisture and heat (*Sax 1979).
Incompatibility (Materials to Avoid): Reacts violently with alcohol,
turpentine, charcoal, and organic refuse (*Merck 1983). Reacts explosively
with metallic powders, carbides, and hydrogen sulfide (*NFPA 1978).
Powerful reducing agents may cause explosion (*Sax 1975).
Hazardous Decomposition or Byproducts: Will react with water or steam to
produce heat, and toxic and corrosive fumes. When heated to decomposition,
it emits nitrogen oxides (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacture of organic and inorganic nitrates, many different
organic chemicals, dye intermediate, Pharmaceuticals, jewelry and
explosives (*SRI; *Merck 1983; *Encyc Occupat Health and Safety 1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away. Isolate the hazard area and deny entry.
Stay upwind and keep out of low areas. Ventilate closed spaces before
entering them (*DOT 1984). Ventilate area of spill or leak. Flush
with copious quantities of water and neutralize with alkaline material
(such as soda ash, lime, etc.) (*NIOSH/OSHA 1981). Keep combustibles
(wood, paper, oil, etc.) away from spilled material. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors; do not get water inside container. Small spills: flush area
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CAS Registry Number: 7697-37-2
Page 4 of 4
NITRIC ACID
SECTION VII (continued)
with flooding amounts of water. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 44).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene GOOD/LIMITED
CPE GOOD/LIMITED
Chlorobutyl GOOD/LIMITED
Neoprene GOOD/LIMITED
Nitrile POOR/LIMITED*
PE GOOD/LIMITED
PVC POOR/MANY
Saranex GOOD/LIMITED
Teflon POOR/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7697-37-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
NITRIC ACID
(7697-37-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Nitric acid is extremely corrosive. Avoid contact with mists and
decomposition fumes.
Substance Characteristics:
Pure Form - Colorless or yellow liquid.
Odor - Sharp and biting.
Commercial Forms - 56, 68, and 70% pure, in water solution.
Uses - Chemical intermediate, fertilizer, veterinary medication,
Pharmaceuticals, explosives, steel pickling, manufacture of organic and
inorganic nitrates, photoengraving.
Materials to Avoid - Alcohols, metal powders.
Other Names - Aqua Fortis, Azotic acid, Engraver's acid, hydrogen nitrate,
Nital, nitrous fumes; nitryl hydroxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
-------
EFATG
CAS Registry Number: 7697-37-2
Page 2 of 3
NITRIC ACID
*
Signs and Symptoms of Acute Nitric Acid Exposure:
Warning: Nitric acid is extremely corrosive. Caution is advised.
Signs and symptoms of acute ingestion of nitric acid may be severe and include
increased salivation, intense thirst, difficulty swallowing, chills, pain, and
shock. Oral, esophageal, and stomach burns are common. Vomitus generally has
a coffee-ground appearance. The potential for circulatory collapse is high
following ingestion of nitric acid.
Acute inhalation exposure may result in sneezing, hoarseness, choking,
laryngitis, dyspnea (shortness of breath), respiratory tract irritation, and
chest pain. Bleeding of nose and gums, ulceration of the nasal and oral
mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur.
If the eyes have come in contact with nitric acid, irritation, pain, swelling,
corneal erosion, and blindness may occur. Dermal exposure may result in severe
burns, pain, and dermatitis (red, inflamed skin).
Emergency Life-Support Procedures:
Acute exposure to nitric acid may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to nitric acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 7697-37-2
Page 3 of 3
NITRIC ACID
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to nitric acid.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Rinse mouth with large amounts of water. Instruct victims not to swallow
the water.
3. DO NOT induce vomiting or attempt to neutralize!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
7. RUSH to a health care facility.
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CAS Registry Number: 7719-12-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PHOSPHORUS TRICHLORIDE
CAS Registry Number: 7719-12-2
Synonyms: Phosphine, Trichloro-; Phosphorous Chloride; Phosphorus Chloride
(C16P2); Phosphorus Chloride (PC13); Trichlorophosphine; Phosphorous Trichloride
Chemical Formula: PC1S
Molecular Weight: 137.35
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCSO inhalation
(guinea pig) 0.28 mg/m3/4 hours (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 169°F, 76°C (*Merck 1983)
Specific Gravity (H2O=1): 1.574 at 21°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 100 at 21 °C (*Merck 1983)
Melting Point: -170°F, -112°C (*Merck 1983)
Vapor Density (AIR=1): 4.75 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (*Merck 1983)
Appearance and Odor: Colorless, clear fuming liquid (*Merck 1983);
pungent odor (*NFPA 1978).
-------
CAS Registry Number: 7719-12-2
Page 2 of 4
PHOSPHORUS TRICHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.5 ppm (3 mg/ms) (NIOSH 1987, p. 194)
ACGIH TLV: TWA 0.2 ppm (1.5 mg/m8); STEL 0.5 ppm (3 mg/ms) (*ACGIH 1983)
IDLH: 50 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Sax 1979)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic; it may cause death or permanent injury. Contact is highly
irritating to the skin, eyes, and mucous membranes, and the material is an
irritant through oral and inhalation exposure (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material will not burn (*NFPA 1978). Use
carbon dioxide or dry chemical on fires involving phosphorus trichloride
(*Sax 1979). Do not use water (Weiss 1980, p. 751).
Special Fire Fighting Procedures: Spray cooling water on containers that
are exposed to flames until well after fire is out. Do not get water
inside containers (*DOT 1984).
Unusual Fire and Explosion Hazards: This material will react violently
with water (*NFPA 1978), producing heat and toxic and corrosive fumes (*Sax
1979). When heated to decomposition, it emits highly toxic fumes of
chlorides and phosphorus oxides (*Sax 1979). It may ignite other
combustible materials (*DOT 1984).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*NFPA 1978)
Stable:
Conditions to Avoid: Contact with water, steam, or acids (*Sax 1979).
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CAS Registry Number: 7719-12-2
Page 3 of 4
PHOSPHORUS TRICHLORIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Reacts violently with water.
Reacts explosively with acetic acid, aluminum, chromyl chloride,
diallylphosphite and allyl alcohol, dimethyl sulfoxide, fluorine,
hydroxylamine, iodine monochloride, lead dioxide, nitric acid, nitrous
acid, organic matter, potassium, and sodium (*NFPA 1978).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides and phosphorus oxides (*Sax 1979).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 751)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a chemical intermediate for phosphorus
oxychloride, surfactants, and stabilizers (*SRI). It is also used as an
intermediate for organophosphorus pesticides and for a number of other
applications (*Hawley 1981).
SECTION VII « PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not get water into containers. Do not touch spilled material.
Use water spray to reduce vapors, but do not put water on leak or spill
area. Keep combustibles aw? y from spilled material. Dike spills for later
disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED*
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 7719-12-2
Page 4 of 4
PHOSPHORUS TRICHLORIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may cause dizziness, headache,
anorexia, respiratory difficulties, nausea and vomiting, and swelling. It
can also cause liver and lung disturbances (*Rumack 1975 to Present).
Occupational exposure has caused coughs, bronchitis, pneumonia, and
conjunctivitis (*ACGIH 1980).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature (*DOT 1984). Do not induce vomiting
(*Rumack 1975 to Present).
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CAS Registry Number: 7722-84-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDROGEN PEROXIDE (Concentration greater than 52%)
CAS Registry Number: 7722-84-1
Synonyms: Albone; Albone DS; Hydrogen Dioxide; Hydrogen Dioxide Solution;
Hydroperoxide; Inhibine; Perhydrol; Peroxaan; Superoxol; T-Stuff
Chemical Formula: H2O2
Molecular Weight: 34.02
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 306°F, 152°C (*Merck 1976); (greater than 52% solution) 258°F,
126°C (Dupont MSDS 1985)
Specific Gravity (H2O=1): 1.463 at 0°C (*Merck 1976); 1.29 at 20°C (Weiss,
1986, p. 574); (greater than 52% solution) 1.3 at 20°C (Dupont MSDS 1985)
Vapor Pressure (mmHg): 1 at 15.3°C (Sax 1984, p. 1551)
Melting Point: 31°F, -0.43°C (*Merck 1976); (greater than 52% solution)
-40°F, -40°C (Dupont MSDS 1985)
Vapor Density (AIR=1): 1.02 (calculated) (Dupont MSDS 1985)
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 7722-84-1
Page 2 of 4
HYDROGEN PEROXIDE
SECTION II (continued)
Solubility in Water: Soluble (Hawley 1981, p. 545)
Appearance and Odor: A crystalline solid at low temperatures (*Sax 1979).
Slightly pungent, irritating odor (Dupont MSDS 1985).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (High-strength hydrogen peroxide) TWA 1 ppm (1.4 mg/ms) (NIOSH
1987, p. 138)
ACGIH TLV: TWA 1 ppm (1.5 mg/ms) (ACGIH 1986-87, p. 21)
IDLH: 75 ppm (NIOSH/OSHA 1978, p. 112)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1551)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (Sax 1984, p. 1551)
Health Hazards (Acute, Delayed, and Chronic): Strong irritant to skin,
eyes, and mucous membranes (Sax 1984, p. 1551).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable. Fires should be fought with water
since the use of chemical extinguishants may accelerate decomposition
(*Encyc Occupat Health and Safety 1971). Small fires: water only; no dry
chemical or carbon dioxide. Large fires: flood fire area with water (*DOT
1984).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing. Move container from fire area if you can do it
without risk. Cool containers that are exposed to flames with water from
the side until well after fire is out. For massive fire in cargo area, use
unamnned hose older or monitor nozzles; if this is impossible, withdraw
from area and let fire burn (*DOT 1984).
Unusual Fire and Explosion Hazards: Spontaneous ignition may occur when
contact with combustible materials is made. Oxygen released in
decomposition will promote combustion. Fires can be of the flaring type but
are not explosive unless confined. Vapor concentration greater than 40
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CAS Registry Number: 7722-84-1
Page 3 of 4
HYDROGEN PEROXIDE
SECTION IV (continued)
percent by weight can be decomposed explosively at 1 atmosphere pressure
(*Encyc Occupat Health and Safety 1971). Severe explosion hazard when it
is exposed to heat, mechanical impact, detonation of a blasting cap, or
caused to decompose catalytically (*Martin 1978).
NFPA Flammability Rating: 0
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Hawley 1977)
Conditions to Avoid: Mechanical impact, uncovering the container
(*Sax 1979); contact with combustible materials, light (*Merck 1976);
temperatures above 35°C (*Osol 1975); hot wires, catalytic impurities
(*Encyc Occupat Health and Safety 1971).
Incompatibility (Materials to Avoid): Oxidizable materials including
iron, copper, brass, bronze, chromium, zinc, lead, manganese, silver,
catalytic metals (NIOSH/OSHA 1978, p. 112).
Hazardous Decomposition or Byproducts: Decomposition can build up large
pressures of oxygen and water which may then burst explosively (Sax 1984,
p. 1551).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Bleaching and deodorizing of textiles, wood pulp, hair, fur, etc; source of
organic and inorganic peroxides; pulp and paper industry; plasticizers;
rocket fuel; foam rubber; manufacture of glycerol; antichlor; dyeing;
electroplating; antiseptic; laboratory reagent; epoxidation; hydroxylation;
oxidation and reduction; viscosity control for starch and cellulose
derivatives; refining and cleaning metals; bleaching and oxidizing agent in
foods; neutralizing agent in wine distillation; seed disinfectant;
substitute for chlorine in water and sewage treatment (Hawley 1981, p.
545).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Keep combustibles (wood, paper, oil, etc.)
away from spilled material. Do not touch spilled material; stop leak if you
can do it without risk. Use water spray to reduce vapors; do not get water
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CAS Registry Number: 7722-84-1
Page 4 of 4
HYDROGEN PEROXIDE
SECTION VII (continued)
inside container. Small dry spills: with clean shovel place material
into clean, dry container and cover; move containers from spill area.
Small spills: flush area with flooding amounts of water. Large spills:
dike far ahead of spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED
Butyl/Neoprene GOOD/LIMITED*
Neoprene GOOD/LIMITED*
Nitrile POOR/LIMITED*
PVC POOR/LIMITED
Teflon POOR/LIMITED
Viton GOOD/LIMITED*
Viton/Neoprene GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7722-84-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDROGEN PEROXIDE (>52%)*
(7722-84-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Liquid above 0 degrees C (31 degrees F).
Odor - None.
Commercial Form - 27.5, 35, 50, and 70% pure solutions, usually mixed with
water.
Uses - Manufacture of peroxides and glycerol; pulp and paper industry; metal
refining and cleaning; rocket fuel component; substitute for chlorine in water
and sewage treatment; wine distillation; electroplating; bleaching;
deodorizing; oxygen source; seed disinfectant; antiseptic; manufacture of
cosmetics, plasticizers, and foam rubber.
Materials to Avoid - Oxidizable materials, metals.
Caution: Explosion potential is high. Hydrogen peroxide may ignite
combustable materials.
Other Names - Albone, Inhibine, Perhydrol, Peroxaan, Superoxol, T-stuff.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
*Only concentrations greater than 52% are listed under Section 302 of
SARA Title III.
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EFATG
CAS Registry Number: 7722-84-1
Page 2 of 3
HYDROGEN PEROXIDE
Signs and Symptoms of Acute Hydrogen Peroxide Exposure:
Signs and symptoms of acute exposure to hydrogen peroxide may be severe and
include irritation or burns to the skin, eyes, respiratory tract, mouth,
esophagus, stomach, and intestines. Distension or rupture of the stomach and
other hollow viscera may occur; vomiting is common. Corneal ulceration may
develop.
Emergency Life-Support Procedures:
Acute exposure to hydrogen peroxide may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrogen peroxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrogen peroxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
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EFATG
CAS Registry Number: 7722-84-1
Page 3 of 3
HYDROGEN PEROXIDE
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
6. Transport to a health care facility.
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CAS Registry Number: 7723-14-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHORUS
CAS Registry Number: 7723-14-0
Synonyms: Black Phosphorus; Bonide Blue Death Rat Killer; Common Sense
Cockroach and Rat Preparations; Exolit LPKN; Exolit VPK-n361; Phosphorus
(White); Phosphorus (Yellow); Phosphorus (Red); Phosphorus, White, Molten
(Dry); Phosphorus-31; Rat-Nip; Red Phosphorus; Violet Phosphorus
Chemical Formula: P
Molecular Weight: 30.97
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 3.03 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: White/Yellow: 536°F, 280°C (*Weast 1979) (ignites at
86°F, 30°C in moist air) (Merck 1983, p. 1060); Red: 536°F, 280°C (ignites
at 500°F, 260°C) (Merck 1983, p. 1060)
Specific Gravity (H2O=1): Red: 2.34; Violet: 2.36; Black: 2.70;
White/Yellow: 1.8 at 20°C (*Weast 1979)
Vapor Pressure (mmHg): White/Yellow: 0.026 at 20°C (*NIOSH/OSHA 1981)
Melting Point: White/Yellow: 111.2°F, 44.1 °C; Violet: 1094°F, 590°C;
Red: 1094°F, 590°C at 43 atm (*Weast 1979)
Vapor Density (AIR=1): Red: 4.77; White/Yellow: 4.42 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: White/Yellow: 1 part/300,000 parts water. Black:
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CAS Registry Number: 7723-14-0
Page 2 of 4
PHOSPHORUS
SECTION II (continued)
Very slightly soluble in cold water, insoluble in hot water (*Weast 1979).
Appearance and Odor: White/Yellow: White to yellow, soft, waxy solid
(*NIOSH/OSHA 1981). It has a garlic-like odor (*Hayes 1983). Black:
Polymorphic, orthorhombic crystalline form, amorphous form;. Red: Red to
violet powder; polymorphic (Merck 1983, pp. 1059-1060). Violet: Violet
monoclinic (*Weast 1979).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Yellow or white phosphorus) 0.1 mg/m8 (NIOSH 1987, p. 194)
ACGIH TLV: (Yellow phosphorus) TWA 0.1 mg/ms (ACGIH 1986-87, p. 27)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*NIOSH/OSHA 1981)
Skin: Yes (*NIOSH/OSHA 1981)
Ingestion: Yes. Red is not poisonous unless
contaminated with Yellow (*Gosselin 1976).
Health Hazards (Acute, Delayed, and Chronic): It is classified as super
toxic. The probable lethal dose is less than 5 mg/kg (a taste or less than
7 drops) for 70 kg (150 Ib.) person (*Gosselin 1976). Poisonous if
swallowed or if fumes are inhaled (DOT 1984, Guides 32, 38). Yellow:
Fumes are irritating to the respiratory tract and cause severe ocular
irritation. On contact with the skin it may ignite and produce severe skin
burns with blistering (*NIOSH/OSHA i981). Red: Irritates eyes (*DASE
1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: White/Yellow: Can be ignited under almost all normal
temperature conditions. Red: Material that must be preheated before
ignition can occur (*NFPA 1978).
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, sand, water spray, or
foam. Large fires: water spray, fog, or foam. Cool containers that are
exposed to flames with water from the side until well after fire is out
(DOT 1984, Guides 32, 38).
Special Fire Fighting Procedures: White/Yellow: Deluge with water,
taking care not to scatter, until fire is extinguished and phosphorus has
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CAS Registry Number: 7723-14-0
Page 3 of 4
PHOSPHORUS
SECTION IV (continued)
solidified, then cover with wet sand or dirt. Red: Flood with water and
when fire is extingushed, cover with wet sand or dirt. Extreme caution
should be used during clean up since reignition may occur. Under certain
conditions at high temperature, red phosphorus reverts to more hazardous
white phosphorus (*NFPA 1978).
Unusual Fire and Explosion Hazards: Will reignite itself after fire is
extinguished (*DOT 1984). White/Yellow: Ignites at approximately 86°F,
30°C in air; ignition temperature is higher when air is dry. Black: Does
not catch fire spontaneously. Red: Catches fire when heated in air to
approximately 500°F, 260°C and burns with formation of the pentoxide. Burns
when heated in atmosphere of chlorine. Caution: Avoid contact with
potassium chlorate, potassium permanganate, peroxides and other oxidizing
agents; explosions may result on contact or friction (Merck 1983,
pp. 1059-1060).
NFPA Flammability Rating: 3 (white or yellow); 1 (red)
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes White/Yellow: Darkens on exposure to light
(Merck 1983, pp. 1059-1060). Gives off acrid
fumes on exposure to air (*NIOSH/OSHA 1981).
Ignites spontaneously in air at or above 30C
(Merck 1983, pp. 1059-1060).
Stable: Yes. Black: stable in air (Merck 1983, pp.
1059-1060).
Conditions to Avoid: Avoid heat. Red: burning yields toxic oxides
of phosphorus ("CHRIS 1978); White/Yellow: toxic gases and \npors
such as phosphoric acid fumes are released (*NIOSH/OSHA 1981).
Incompatibility (Materials to Avoid): Red: Avoid uncontrolled contact
with oxidizing agents, or with strong alkaline hydroxides. Can react
violently with oxidizing agent in presence of air and moisture, liberating
phosphorus acids and toxic, spontaneously flammable phosphine gas (*CHRIS
1978). White/Yellow: Air, all oxidizing agents including elemental
sulfur, strong caustics (NIOSH/OSHA 1978, p. 156).
Hazardous Decomposition or Byproducts: Upon heating Red releases toxic
oxides of phosphorus (*CHRIS 1978) and Yellow emits toxic gases and vapors
such as phosphoric acid fumes (*NIOSH/OSHA 1981).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
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CAS Registry Number: 7723-14-0
Page 4 of 4
PHOSPHORUS
SECTION VI -- USE INFORMATION
Major uses: rat poison; for smoke screens; gas analysis; fireworks;
manufacturing safety matches, phosphoric acid, phosphine, phosphoric
anhydride, phosphorus pentachloride, phosphorus trichloride, fertilizers,
pesticides, smoke bombs, incendiary shells, tracer bullets; in organic
synthesis (Merck 1983, pp. 1059-1060).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas (*DOT 1984). Any clothing which becomes
contaminated should be removed immediately (*NIOSH/OSHA 1981).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7723-14-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHOSPHORUS
(7723-14-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White or yellow: crystalline, waxlike transparent solid;
Red: violet-red, amorphous powder; Black: solid resembling graphite.
Odor - Garliclike.
Commercial Forms - White or yellow: shipped under water in steel drums or
tank cars; Red: in tins and drums.
Uses - Rat poison, fertilizers, pesticides, and other phosphorus-containing
compounds; organic synthesis; manufacture of safety matches, fireworks, smoke
bombs, incendiary shells, tracer bullets, and semiconductors.
Caution: Flammable solid. Avoid sources of extreme heat or ignition including
sparks or fire. White (or yellow) phosphorus may spontaneously ignite on
contact with damp surfaces, including water or skin. Phosphorus will liberate
toxic gases and vapors when heated.
Materials to Avoid - Oxidizers, alkali, water (except for use in emergency life
support).
Other Names - Exolit LPKN, Exolit VPK-n361, Rat-Nip.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, copper sulfate, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbital, dopamine, norepinephrine.
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EFATG
CAS Registry Number: 7723-14-0
Page 2 of 3
PHOSPHORUS
Signs and Symptoms of Acute Phosphorus Exposure:
Signs and symptoms of acute exposure to phosphorus may be severe and occur in
three stages. The first stage will involve burns, pain, shock, intense
thirst, nausea, vomiting, diarrhea, severe abdominal pain, and "smoking
stools." The breath and feces may have garlicky odor. The second stage will
be a symptom-free period of several days in which the patient appears to be
recovering. The third stage may be severe and include nausea, bloody vomitus,
diarrhea (may be bloody), jaundice, liver enlargement with tenderness, renal
damage, hematuria (bloody urine), and either oliguria (little urine formation)
or anuria (no urine formation). Headache, convulsions, delirium, coma, cardiac
arrhythmias, and cardiovascular collapse may also occur.
If phosphorus contacts the eyes, then severe irritation and burns,
blepharospasm (spasmodic winking), lacrimation (tearing), and photophobia
^heightened sensitivity to light) may occur. Eye contact may lead to a total
destruction of the eyes. Victims may experience spontaneous hemorrhaging of
phosphorus-contaminated skin and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to phosphorus may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosphorus.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
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CAS Registry Number: 7723-14-0
Page 3 of 3
PHOSPHORUS
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosphorus.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. Brush nonadherent phosphorus from skin areas, then flush skin with water.
Immerse exposed skin areas in water or cover with a wet dressing.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
AT LEAST 15 MINUTES. Keep exposed eyes covered with wet compresses.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
4. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
5. Ambulate (walk) and give water to the victims.
6. RUSH to a health care facility.
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CAS Registry Number: 7726-95-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985 .
Revision: November 30, 1987
CHEMICAL IDENTITY ~ BROMINE
CAS Registry Number: 7726-95-6
Synonyms: No Synonyms Found
Chemical Formula: Br2
Molecular Weight: 159.81
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 139.2°F, 59.5°C (*Merck 1976)
Specific Gravity (H2O=1): 3.1023 at 25°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 172 at 20.6°C (*Patty 1963)
Melting Point: 19.0°F, -7.25°C (*Merck 1976)
Vapor Density (AIR=1): 5.51 at 15°C (Hawley 1981, p. 149)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 3.52 g/100 cc water at 50°C (*Weast 1979)
Appearance and Odor: Heavy dark reddish-brown liquid or vapor (*Merck
1976, *Gosselin 1976, *NFPA 1978); solid forms are also found (*NRC 1980);
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CAS Registry Number: 7726-95-6
Page 2 of 4
BROMINE
SECTION II (continued)
it has a suffocating odor (*Merck 1976).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 ppm (0.7 mg/ms) (OSHA 1984, p. 661)
ACGIH TLV: TWA 0.1 ppm (0.7 mg/ms); STEL 0.3 ppm (2 mg/ms) (*ACGIH 1981)
IDLH: 10 ppm (NIOSH/OSHA 1978, p. 52)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Encyc Occupat Health and Safety 1971)
-Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Inhalation exposure to
11-23 mg/m8 produces severe choking. 30-60 mg/m8 is extremely dangerous.
200 mg/m8 is fatal in a short time. Vapors can cause acute as well as
chronic poisoning. It has cumulative properties (*Encyc Occupat Health and
Safety 1971). It is irritating to the eyes and respiratory tract (*NFPA
1978). Poisoning is due to the corrosive action on the gastrointestinal
tract. Nervous, circulatory and renal disturbances occur after ingestion.
Ingestion of liquid can cause death due to circulatory collapse and
asphyxiation from swelling of the respiratory tract (*Gosselin 1976). The
lowest oral lethal dose reported for humans is 14 mg/kg. The lowest lethal
inhalation concentration reported for humans is 1000 ppm (*NIOSH/RTECS
1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Nonflammable, but a strong oxidizer (NFPA 1984,
p. 49-12). Extinguish with dry chemical, carbon dioxide, water spray, fog
or foam (DOT 1984, Guide 59).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Move containers from fire area.
Cool containers that are exposed to flames with water (DOT 1984, Guide
59).
Unusual Fire and Explosion Hazards: Will cause ignition of organic
materials; spontaneous ignition possible when combined with potassium,
phosphorus and tin (*Encyc Occupat Health and Safety 1971) and a wide
variety of other chemicals (Sax 1984, p. 519). It reacts explosively with
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CAS Registry Number: 7726-95-6
Page 3 of 4
BROMINE
SECTION IV (continued)
acetylene, acrylonitrile, ammonia, dimethyl formamide, ethyl phosphine,
hydrogen, isobutyrophenone, nickel carbonyl, nitrogen triiodide, ozone,
oxygen difluoride, phosphorus, potassium, silver azide, sodium and sodium
carbide (*NFPA 1978).
NFPA Flammability Rating: 0
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (NFPA 1984, p. 49-21)
Conditions to Avoid: Vaporizes rapidly at room temperature (Merck
1983, p. 192)
Incompatibility (Materials to Avoid): Bromine is incompatible with a wide
variety of materials including alkali hydroxides; arsenites; ferrous,
mercurous salts; hypophosphites and other oxidizable substances (Merck
1983, p. 192).
Hazardous Decomposition or Byproducts: When heated it emits highly toxic
fumes and will react with water or steam to product toxic and corrosive
fumes (Sax 1980, p. 519).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
For gold extraction; military gas; bleaching fibers and silks; manufacture
of medicinal bromine compounds, anti-knock compounds (ethylene bromide) for
gasoline (*Merck 1976). For fire-retardant for plastics; in photography;
shrink-proofing wool; in organic synthesis; solvents; intermediate for
fumigants; fire-extinguishing fluid; and analytical reagents (*Hawley
1977). Also used as a refrigerant and dehumidifying agent and for swimming
pool sanitation and water purification (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill or leak. Collect for reclamation by absorbing it
ia vermiculite, dry sand, earth, or a similar material and disposing in
sealed containers in secured sanitary landfill (*NIOSH/OSHA 1981).
Potassium carbonate, sodium carbonate, sodium bicarbonate, lime, and sodium
hydroxide solutions are neutralizing agents for liquid bromine spills
(*Clayton and Clayton 1981-82). Do not touch material, stop leak if
possible without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other noncombustible absorbent material and place in
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CAS Registry Number: 7726-95-6
Page 4 of 4
BROMINE
SECTION VII (continued)
container. Large spills: dike spill for later disposal (DOT 1984, Guide
59).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
PE POOR/MANY
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7726-95-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
BROMINE
(7726-95-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Bromine toxicity can occur via inhalation, dermal/eye contact, or
ingestion. Special personal protective equipment may be required. Caution is
advised.
Substance Characteristics:
Pure Forms - Dark reddish-brown liquid; solid below -7 degrees C (19
degrees F).
Note: Bromine has a significant vapor pressure.
Odor - Suffocating.
Commercial Form - Liquid in bottles, drums, tank cars, tank trucks.
Uses - Swimming pool sanitation; water purification; bleaching; shrink
proofing; gold extraction; intermediate for gasoline additives, fire
retardants, fumigants, and refrigerants.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, isoproterenol
inhaler, normal saline, D5W, Ringer's lactate.
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EFATG
CAS Registry Number: 7726-95-6
Page 2 of 3
BROMINE
Signs and Symptoms of Acute Bromine Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
Signs and symptoms of acute exposure to bromine may include hypotension (low
blood pressure), tachycardia (rapid heart rate), cyanosis (blue tint to the
skin and mucous membranes), and circulatory collapse. Neurological effects
may include headache, dizziness, delirium, stupor, and shock.
Gastrointestinal effects may include vomiting (vomitus may be blue), diarrhea,
abdominal pain, and bloody stools. Nephritis with oliguria (scanty urination)
and anuria (absence of urine formation) has been reported. Bromine is
irritating to the skin, eyes, and mucous membranes; brown discoloration of the
mucous membranes, lips, and tongue may be observed. Lacrimation (tearing),
-photophobia (heightened sensitivity to light), nosebleeds, coughing,
asphyxiation, and pulmonary edema may also occur. A burning pain in the mouth
and esophagus generally follows ingestion.
Emergency Life-Support Procedures:
Acute exposure to bromine may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying and supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to bromine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 7726-95-6
Page 3 of 3
BROMINE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to bromine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed IMMEDIATELY with
lukewarm water for at least 15 minutes.
5. IMMEDIATELY wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
6. Transport to a health care facility.
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CAS Registry Number: 7778-44-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CALCIUM ARSENATE
CAS Registry Number: 7778-44-1
Synonyms: Arsenic Acid, Calcium Salt (2:3); Calcium Arsenate, Solid (DOT);
Calcium Orthoarsenate; Calcium-O-Arsenate; Calciumarsenat; Chip-Cal Granular;
Cucumber Dust; FLAG; KALO; Kilmag; Pencal; Security; Spra-Cal; Spracal;
Tricalcium Arsenate; Tricalcium Ortho-Arsenate; Tricalcium-O-Arsenate
Chemical Formula: As2O8 3Ca
Molecular Weight: 398.08
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 3.620 (*Clayton and Clayton 1981-82)
Vapor Pressure (mmHg): Not Found
Melting Point: 1455°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.13 g/liter at 77°F, 25°C (*Clayton and Clayton
1981-82)
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CAS Registry Number: 7778-44-1
Page 2 of 4
CALCIUM ARSENATE
SECTION II (continued)
Appearance and Odor: Colorless (*Weast 1979) or white powder (*Worthing
1979); odorless (*CHRIS 1978)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.01 mg/rn8, as arsenic (NIOSH 1987, p. 68)
ACGIH TLV: (Arsenic and soluble compounds) TWA 0.2 mg/ms as arsenic
(ACGIH 1986-87, p. 10)
IDLH: 100 mg/m8 (NIOSH/OSHA 1978, p. 58)
Other Limits Recommended: Occupational exposure to inorganic arsenic
recommended standard — Ceiling concentration 0.002 mg/ms/15 minutes, air
(*NIOSH/RTECS 1985). NIOSH occupational carcinogen (NIOSH 1987, P. 68)
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Not Found
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose for humans is 5-50 rag/kg, or between 7
drops and 1 teaspoonful for a 150 Ib. person (*Gosselin 1976). It is an
irritant to eyes, respiratory tract, mouth and stomach (*CHRIS 1978).
Damage to kidneys, liver and the nervous system have been reported (*Rumack
1975 to Present). (Non-Specific -- Arsenic) Chronic exposure can cause
bone marrow damage, often leading to aplastic anemia. There is
epidemiological evidence that chronic ingestion of arsenic compounds causes
a predisposition to skin cancers (*Gilman 1980).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not flammable (Weiss 1980, p. 210) For small
fires, use dry chemical, water spray, or foam. For large fires, use water
spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear self-contained (positive pressure if available) breathing apparatus
and full protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases (*DOT 1984).
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CAS Registry Number: 7778-44-1
Page 3 of 4
CALCIUM ARSENATE
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1986, p. 219)
Conditions to Avoid: Heat ("Hawley 1977)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition,
calcium arsenate produces toxic fumes of arsenic (Sax 1984, p. 317).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 210)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide and herbicide (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Stay upwind; keep out of low areas. Do not touch spilled material.
Take up small solution spills with sand or other noncombustible
absorbent material and place into containers for later disposal.
For small dry spills, use clean shovel to place material in clean,
dry container. For large spills, dike far ahead of spill for later
disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7778-44-1
Page 4 of 4
CALCIUM ARSENATE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7778-44-1
Page 1 of 4
Emergency First Aid Treatment Guide
for
CALCIUM ARSENATE
(7778-44-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless or white powder.
Odor - None.
Commercial Form - 70% pure mixture with calcium carbonate and calcium
hydroxide.
Uses - Pesticide.
Caution: Avoid sources of heat including fire. Calcium arsenate will liberate
toxic arsenic fumes when heated to decomposition.
Other Names - Cucumber dust, FLAG, KALO, Kilmag, Pencal, Spracal, tricalcium
arsenate, tricalcium ortho-arsenate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
dopamine, norepinephrine, sodium bicarbonate, dimercaprol, penicillamine,
isoproterenol.
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EFATG
CAS Registry Number: 7778-44-1
Page 2 of 4
CALCIUM ARSENATE
Signs and Symptoms of Acute Calcium Arsenate Exposure:
Warning: Effects usually appear within 30 minutes of exposure but may be
delayed for several hours. Caution is advised.
Hypotension (low blood pressure), tachycardia (rapid heart rate), dehydration,
intense thirst, difficulty swallowing, vomiting, abdominal pain, and diarrhea
are among the first signs and symptoms noticed following acute calcium arsenate
exposure. Headache, conjunctivitis (red, inflamed eyes), runny nose, and
lacrimation (tearing) are also common. Garlic odor of breath and feces may be
noted.
Cardiovascular effects include shock, tachycardia (rapid heart rate),
ventricular fibrillation, and other cardiac abnormalities. Pulmonary edema may
occur. Altered mental status, seizures, and delirium are further complications
of calcium arsenate exposure. Intense muscle cramping is common. Exposure to
airborne dust is generally accompanied by irritation of exposed skin, eyes, and
mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to calcium arsenate may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to calcium arsenate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. RUSH to a health care facility!
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
-------
EFATG
CAS Registry Number: 7778-44-1
Page 3 of 4
CALCIUM ARSENATE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to calcium arsenate.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
6. RUSH to a health care facility!
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of calcium arsenate is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 5. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of calcium arsenate may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 5.
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EFATG
CAS Registry Number: 7778-44-1
Page 4 of 4
CALCIUM ARSENATE
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
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CAS Registry Number: 7782-41-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FLUORINE
CAS Registry Number: 7782-41-4
Synonyms: Fluorine-19
Chemical Formula: F2
Molecular Weight: 38.0
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.23 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -306.6°F, -188.13°C (*Merck 1983)
Specific Gravity (H2O=1): 1.5127 at -306.6°F, -188.13°C (liquid) (*Merck
1983)
Vapor Pressure (mmHg): 760 at -306.2°F, -187.9°C (*Weast 1979)
Melting Point: -363.3°F, -219.6°C (*Merck 1983)
Vapor Density (AIR=1): 1.695 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Reacts with water (*Merck 1983)
Appearance and Odor: Pale yellow to greenish yellow gas having a
characteristic pungent odor (*Merck 1983; *Weast 1979).
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CAS Registry Number: 7782-41-4
Page 2 of 4
FLUORINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 ppm (0.2 mg/ms) (NIOSH 1987, p. 128)
ACGIH TLV: TWA 1 ppm (2 mg/ms); STEL 2 ppm (4 mg/ms) (*ACGIH 1984)
IDLH: 25 ppm (NIOSH/OSHA 1978, p. 104)
Other Limits Recommended: EEGL 7.5 ppm (60 minutes) (NRC 1984a, pp.
77-88).
Routes of Entry: Inhalation: Yes (*Merck 1983)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Poisonous; may be fatal if
inhaled. Vapor extremely irritating. Contact may cause burns to skin and
eyes (*DOT 1984). Chronic absorption may cause osteosclerosis and
calcification of ligaments (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fire, use dry chemical or carbon
dioxide. For large fire, use water spray, fog, or foam. For massive fire
in cargo area, use unmanned hose holder or monitor nozzles (*DOT 1984).
Special Fire Fighting Procedures: A few whiffs of the gas or vapor could
cause death. Gas, vapor or liquid could be fatal on penetrating the
firefighters' normal full protective clothing. Only special protective
clothing designed to protect against fluorine should be used; the normal
full protective clothing available to the average fire department will not
provide adequate protection. Do not direct water onto fluorine leaks as
the fire may be intensified (*NFPA 1978).
Unusual Fire and Explosion Hazards: May ignite other combustible
materials (wood, paper, oil, etc.) Mixture with fuels may explode.
Container may explode in heat of fire. Vapor explosion and poison hazard
indoors, outdoors, or in sewers (*DOT 1984).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
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CAS Registry Number: 7782-41-4
Page 3 of 4
FLUORINE
SECTION V (continued)
Conditions to Avoid: Keep gas in tank, avoid exposure to all other
materials (*Merck 1983)
Incompatibility (Materials to Avoid): Avoid contact with all oxidizable
materials, including organic materials (*Merck 1983). Will react violently
with water and most organic materials to produce heat and toxic fumes (*Sax
1979).
Hazardous Decomposition or Byproducts: Poisonous gas is produced in fire
(*CHRIS 1980).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Manufacture of fluorochemicals and plastics; rocket propellant (*Weast
1979). Chemical intermediate for sulfur hexafluoride, chlorine
trifluoride, bromine trifluoride, uranium hexafluoride, molybdenum
hexafluoride, perchloryl fluoride, oxygen difluoride (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe gas or vapor; do not allow vapor to contact skin or eyes
(see Section III above). Stop leak if you can do it without risk.
Use water spray to reduce vapors but do not put water on leak or spill
area. Isolate area until gas has dispersed. A fine water spray
applied to the edge of the spill pool will start a hot flare fire
which will burn the spilled material. (Use extreme caution.)
(*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7782-41-4
Page 4 of 4
FLUORINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED*
Neoprene GOOD/LIMITED*
PVC GOOD/LIMITED*
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation of fluorine causes coughing,
choking, and chills. An asymptomatic period of 1 to 2 days followed by
fever, cough, tightness in chest, rales, and cyanosis indicate pulmonary
edema (*Dreisbach 1977). Small amounts of gas in air can have a strong
caustic effect on the cornea, eyelids, nose (*Grant 1974, *Merck 1983).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, establish respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin and eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed; keep victim under observation. (*DOT 1984).
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CAS Registry Number: 7782-50-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLORINE
CAS Registry Number: 7782-50-5
Synonyms: Bertholite; Molecular Chlorine
Chemical Formula: C12
Molecular Weight: 70.91
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.4 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): Yes
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -30.3°F, -34.6°C (*Weast 1983)
Specific Gravity (H2O=1): 1.424 at 15°C (Weiss 1986, p. 252)
Vapor Pressure (mmHg): 7600 at 30°C (*Weast 1983)
Melting Point: -150°F, -101°C (*Weast 1983)
Vapor Density (AIR=1): 2.49 (Sax 1986, p. 32)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.57 g/100 mL at 30°C (*Weast 1983)
Appearance and Odor: Greenish-yellow gas with suffocating odor (*Merck
1983).
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CAS Registry Number: 7782-50-5
Page 2 of 4
CHLORINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 1 ppm, 3 mg/ms (OSHA 1984)
ACGIH TLV: TWA 1 ppm (3 mg/ms); STEL 3 ppm (9 mg/m8) (*ACGIH 1980)
IDLH: 30 ppm (NIOSH 1987, p. 74)
Other Limits Recommended: Occupational Exposure to Chlorine Recommended
Standard: 15-minute ceiling 0.5 ppm (*NIOSH/RTECS 1985); EEGL 3.0 ppm
(60 minutes) (NRC 1984b, pp. 5-11)
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 64)
Skin: Yes (NIOSH/OSHA 1978, p. 64)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Poisonous; may be fatal if
inhaled. Contact may cause burns to skin and eyes (*DOT 1984).
Medical Conditions Generally Aggravated by Exposure: Bronchitis or
chronic lung conditions (*ITI 1982).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Will not burn, but most combustible materials will
burn in chlorine as they do in oxygen; flammable gases will form explosive
mixtures with chlorine (*NFPA 1978). Dry chemical, carbon dioxide, water
spray, fog or foam (DOT 1984, Guide 20).
Special Fire Fighting Procedures: Evacuate area endangered by gas. Stay
upwind; keep out of low areas. Wear positive pressure breathing apparatus
and full protective clothing. Move container from fire area if you can do
so without risk. Spray cooling water on containers that are exposed to
flames until well after fire is out (DOT 1984, Guide 20). If it is
necessary to stop the flow of gas, use water spray to direct escaping gas
away from those effecting shut-off (*NFPA 1978).
Unusual Fire and Explosion Hazards: May ignite other combustible
materials (wood, paper, oil, etc.). Mixture with fuels may cause
explosion. Container may explode in heat of fire. Vapor explosion and
poison hazard indoors, outdoors or in sewers (DOT 1984, Guide 20).
Hydrogen and chlorine mixtures (5-95%) are exploded by almost any form of
energy (heat, sunlight, sparks, etc.) (*NFPA 1978). May combine with water
or steam to produce toxic and corrosive fumes of hydrochloric acid
(*Environ Canada 1981).
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CAS Registry Number: 7782-50-5
Page 3 of 4
CHLORINE
SECTION IV (continued)
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Heat and contact with hydrogen gas or powdered
metals (*NFPA 1978).
Incompatibility (Materials to Avoid): Plastics and rubber (*NIOSH/OSHA
1981)
Hazardous Decomposition or Byproducts: Emits highly toxic fumes when
heated (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Manufacture of chlorinated lime used in bleaching; manufacture of synthetic
rubber and plastics; purifying water; detinning and dezincing iron (*Merck
1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Keep combustibles (wood, paper, oil, etc.) away from spilled
material. Stop leak of you can do it without risk. Use water spray to
reduce vapor but do not put water on leak or spill area. Isolate area
until gas has dispersed. (*DOT, 1984)
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7782-50-5
Page 4 of 4
CHLORINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl POOR/LIMITED*
Butyl/Neoprene GOOD/LIMITED
CPE GOOD/LIMITED*
Neoprene GOOD/LIMITED
Nitrile POOR/LIMITED*
PE POOR/MANY
PVC POOR/MANY
Saranex GOOD/LIMITED
Viton GOOD/LIMITED
Viton/Neoprene GOOD/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7782-50-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
CHLORINE
(7782-50-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Greenish-yellow gas.
Odor - Pungent, suffocating.
Commercial Forms - Gas in cylinders; liquid in 100- and 150-pound steel
cylinders, tank cars and barges, motor trucks, pipelines.
Uses - Chemical synthesis, swimming pool sanitation, water purification, food
processing, shrink proofing, metal processing, batteries, bleaching agent,
intermediate for gasoline additives, flame-retafdant compounds, refrigerants.
Other Names - Bertholite, molecular chlorine.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, isoproterenol inhaler, sodium bicarbonate.
Signs and Symptoms of Acute Chlorine Exposure:
Warning: Effects may be delayed. Caution is advised. Chlorine is corrosive
and may be converted to hydrochloric acid in the lungs.
Signs and symptoms of acute exposure to chlorine may include tachycardia (rapid
heart rate), hypertension (high blood pressure) followed by hypotension (low
blood pressure), and cardiovascular collapse. Pulmonary edema and pneumonia
are often seen.
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EFATG
CAS Registry Number: 7782-50-5
Page 2 of 3
CHLORINE
The eyes, nose, throat, and chest may sting or burn following exposure to
chlorine. Cough with bloody sputum, a feeling of suffocation, dizziness,
agitation, anxiety, nausea, and vomiting are common. Dermal exposure may
result in sweating, pain, irritation, and blisters.
Emergency Life-Support Procedures:
Acute exposure to chlorine may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as chlorine-resistant plastic sheeting and
disposable bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to chlorine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to chlorine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas for at least 15 minutes with soap and water.
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EFATG
CAS Registry Number: 7782-50-5
Page 3 of 3
CHLORINE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
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CAS Registry Number: 7783-00-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SELENIOUS ACID
CAS Registry Number: 7783-00-8
Synonyms: Monohydrated Selenium Dioxide; Selenous Acid
Chemical Formula: H2O3Se
Molecular Weight: 128.98
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow oral
(rat) 25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000/10,000 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): In Selenium Compounds category
SECTIO?: II — PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 3.004 at 15°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 2 at 15°C (*Merck 1976)
Melting Point: Decomposes at 158°F, 70°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 90 parts/100 parts at 32°F, 0°C (*Merck 1976)
Appearance and Odor: Colorless solid (*Merck 1976, *Weast 1979);
transparent, colorless crystals (Sax 1984, p. 2390)
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CAS Registry Number: 7783-00-8
Page 2 of 3
SELENIOUS ACID
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Selenium compounds) TWA 0.2 mg/m3 as selenium (NIOSH 1987,
(p. 206)
ACGIH TLV: (Selenium compounds) TWA 0.2 mg/ms, as selenium (ACGIH 1986-87,
P-29)
IDLH: Not Found
Other Limits Recommended: Toxicity information: IDLH for selenium compounds
100 mg/m3 (NIOSH 1987, p. 206).
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Selenious acid and its salts
are capable of penetrating the skin and can produce acute poisonings
(*Rumack 1975 to Present). Causes irritations and burns of the skin
(*Friberg 1979). It is highly toxic orally. Inorganic selenium compounds
may cause dermatitis (Sax 1984, p. 2390).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Avoid heating (Sax 1984, p. 2390)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
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CAS Registry Number: 7783-00-8
Page 3 of 3
SELENIOUS ACID
SECTION V (continued)
emits toxic fumes of selenium (Sax 1984, p. 2390)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a reagent for alkaloids and as an oxidizing agent (*Merck
1976). Isotope is used in labeling radiopharmaceuticals (*Nuclear Medicine
Communication 3(4)247 1982).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). Ventilate
area of spill. Collect spilled material in most convenient and safe manner
and deposit in sealed containers for reclamation or disposal in a secured
disposal landfill. Liquid containing selenium inorganic compounds should be
absorbed in vermiculite, dry sand, earth or similar material (*NIOSH/OSHA
1981).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breath ng apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Toxic effects are similar to those of
selenium and other selenium compounds. Garlic odor of breath is a common
symptom. Pallor, nervousness, depression, and digestive disturbances have
been reported in cases of chronic exposure (Sax 1984, p. 2390). The most
common industrial injuries are irritations and burns of the skin (*Friberg
1979).
Emergency and First Aid Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
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CAS Registry Number: 7783-06-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- HYDROGEN SULFIDE
CAS Registry Number: 7783-06-4
Synonyms: Dihydrogen Monosulfide; Dihydrogen Sulfide; Hydrogen Sulphide;
Hydrosulfuric Acid; Sewer Gas; Stink Damp; Sulfur Hydride; Sulfureted Hydrogen
Chemical Formula: H2S
Molecular Weight: 34.08
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302:
Chemical does not meet the toxicity criteria but because of its
high production volume and recognized toxicity it is considered
a chemical of concern.
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -76.59°F, -60.33°C (*Merck 1976)
Specific Gravity (H2O=1): 0.916 at -60°C (Liquid) (Weiss 1980, p. 518);
1.54 g/L at 0°C (*Merck 1976)
Vapor Pressure (mmHg): 20 atmospheres at 25.5°C (*Weast 1979)
Melting Point: -121.9°F, -85.49°C (*Merck 1976)
Vapor Density (AIR=1): 1.19 (*Merck 1976)
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 7783-06-4
Page 2 of 4
HYDROGEN SULFIDE
SECTION II (continued)
Solubility in Water: 1 gram dissolves in 242 mL at 20°C (*Merck 1976)
Appearance and Odor: Colorless gas with the characteristic odor of rotten
eggs (*Weast 1979; *Merck 1976).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Ceiling 20 ppm; Peak 50 ppm, 10 minutes (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 10 ppm (14 mg/m3); STEL 15 ppm (21 mg/m3) (*ACGIH 1980)
IDLH: 300 ppm (NIOSH/OSHA 1978, p. 112)
Other Limits Recommended: NIOSH: 10 ppm 10-minute ceiling (NIOSH 1987,
p. 140). EEGL 10.0 ppm (24 hour) (NRC 1985a, pp. 55-68).
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Exposure to very high
concentrations causes immediate death (Sax 1984, p. 1552). Also death or
permanent injury may occur after very short exposure to small quantities
(*Sax 1975). It acts directly upon the nervous system resulting in
paralysis of respiratory centers (*Casarett 1975).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: 4.3% (*NFPA 1978)
UEL: 45% (*NFPA 1978)
f
Extinguishing Methods: A very flammable gas (*NFPA 1978). For small
fires let burn unless leak can be stopped immediately. For large fires,
use water spray, fog or foam (*DOT 1984).
Special Fire Fighting Procedures: Stop flow of gas. Use water to keep
fire-exposed containers cool and to protect men effecting the shut-off
(*NFPA 1978). Keep unnecessary people away; isolate hazard area and deny
entry. Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Wear positive pressure breathing apparatus and special
protective clothing. Evacuate area endangered by gas. Move container from
fire area. Stay away from ends of tanks. Withdraw immediately in case of
rising sound from venting safety device or any discoloration on tank due to
fire. Cool containers with water using unmanned device until well after
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CAS Registry Number: 7783-06-4
Page 3 of 4
HYDROGEN SULFIDE
SECTION IV (continued)
the fire is out. Isolate for one-half mile in all directions if tank car
or truck is involved in fire (*DOT 1984).
Unusual Fire and Explosion Hazards: Compound is heavier than air and may
travel a considerable distance to source of ignition and flash back. It
forms explosive mixtures with air over a wide range. Also reacts
explosively with bromine pentafluoride, chlorine trifluoride, nitrogen
triiodide, nitrogen trichloride, oxygen difluoride, and phenyl diazonium
chloride (*NFPA 1978). When heated to decomposition, it emits highly toxic
fumes of oxides of sulfur (Sax 1984, p. 1552).
NFPA Flammability Rating: 4
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*NFPA 1978)
Conditions to Avoid: Avoid physical damage to containers; sources of
ignition; storage near nitric acid, strong oxidizing materials, and
corrosive liquids or gases (*NFPA 1978).
Incompatibility (Materials to Avoid): Incompatible with many materials
including strong oxidizers, metals (NIOSH/OSHA 1978, p. 112), strong nitric
acid, bromine pentafluoride, chlorine trifluoride, nitrogen triiodide,
nitrogen trichloride, oxygen difluoride and phenyl diazonium chloride
(*NFPA 1978).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of oxides of sulfur (Sax 1984, p. 1552).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Used in the manufacturing of chemicals; in metallurgy; analytical reagent;
agricultural disinfectant; intermediate for sulfuric acid, elemental
sulfur, sodium sulfide, and other inorganic sulfides; additives in extreme
pressure lubricants and cutting oils; and as an intermediate for organic
sulfur compounds (*Merck 1976; *Encyc Occupat Health and Safety 1971;
*SRI). Not registered as a pesticide in the U.S. (USEPA/Pesticide Index
1985).
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CAS Registry Number: 7783-06-4
Page 4 of 4
HYDROGEN SULFIDE
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Do not touch spilled material; stop leak if you can do it
without risk. Shut off ignition sources; no flares, smoking or flames in
hazard area. Use water spray to reduce vapors. Isolate area until gas has
dispersed. (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED*
CPE GOOD/LIMITED*
Neoprene GOOD/LIMITED*
PVC GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7783-06-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
HYDROGEN SULFIDE
(7783-06-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Caution: Hydrogen sulfide toxicity can occur via inhalation or dermal/eye
contact, and death may occur within minutes. IMMEDIATELY begin administering
100% oxygen and RUSH victims to a health care facility!
Substance Characteristics:
Pure Forms - Colorless gas or liquid under pressure.
Odor - Similar to rotten eggs.
Commercial Forms - Gas in steel cylinders, or liquid at 350 to 400 psi in
60-ton tank cars.
Uses - Metallurgy, analytical reagent, agricultural disinfectant, chemical
intermediate.
Materials to Avoid - Oxidizers, metals, halogenated compounds.
Caution: Highly flammable. Explosion potential is high. Avoid sources of
extreme heat or ignition including sparks or fire. Combustion produces
irritating sulfur oxides. Hydrogen sulfide may react explosively with strong
oxidizers.
Other Names - Hydrosulfuric acid, sulfur hydride, sulfureted hydrogen.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, diazepam, phenytoin, phenobarbital, dopamine, norepinephrine,
amyl nitrite, sodium nitrite, pyridoxine, atropine.
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CAS Registry Number: 7783-06-4
Page 2 of 3
HYDROGEN SULFIDE
Signs and Symptoms of Acute Hydrogen Sulfide Exposure:
Warning: Caution is advised. Vital signs should be monitored closely.
Signs and symptoms of acute exposure to hydrogen sulfide may include
tachycardia (rapid heart rate) or bradycardia (slow heart rate), hypotension
(low blood pressure), cyanosis (blue tint to skin and mucous membrane), cardiac
palpitations, and cardiac arrhythmias. Dyspnea (shortness of breath),
tachypnea (rapid respiratory rate), bronchitis, pulmonary edema, respiratory
depression, and respiratory paralysis may occur.
Neurological effects include giddiness, irritability, drowsiness, weakness,
confusion, delirium, amnesia, headache, sweating, and dizziness. Muscle
cramping, tremor, excessive salivation, cough, convulsions, and coma may be
noted. Nausea, vomiting, and diarrhea are commonly seen. Exposure to hydrogen
sulfide gas may result in skin irritation, lacrimation (tearing), inability to
detect odors, photophobia (heightened sensitivity to light), and blurred
vision.
Emergency Life-Support Procedures:
Acute exposure to hydrogen sulfide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to hydrogen sulfide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility!
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CAS Registry Number: 7783-06-4
Page 3 of 3
HYDROGEN SULFIDE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to hydrogen sulfide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas for at least 15 minutes with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility!
Ingestion Exposure: No information is available.
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CAS Registry Number: 7783-07-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - HYDROGEN SELENIDE
CAS Registry Number: 7783-07-5
Synonyms: Dihydrogen Selenide; Selane; Selenium Anhydride; Selenium
Dihydride; Selenium Hydride
Chemical Formula: H2Se
Molecular Weight: 80.98
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(guinea pig) 0.28 mg/liter/10 minutes (*NIOSH/RTECS 1985)
TPQ: 10 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Selenium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -42.3°F, -41.3°C (*Merck 1976)
Specific Gravity (H2O=1): 2.12 at -42°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 6536 at 18°C; 9120 at 30.8°C (*Merck 1976)
Melting Point: -86.31°F, -65.73°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 270 ml in 100 ml at 72.5°F, 22.5°C (*Merck 1976)
Appearance and Odor: Colorless gas with an odor resembling decayed
horseradish (*Patty 1963)
-------
CAS Registry Number: 7783-07-5
Page 2 of 4
HYDROGEN SELENIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.05 ppm (0.2 mg/ms) (NIOSH 1987, p. 138)
ACGIH TLV: TWA 0.05 ppm (0.2 mg/ms) (ACGIH 1986-87, p. 21)
IDLH: 2 ppm (NIOSH/OSHA 1978, p. 112)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (DOT 1984, Guide 18)
Skin: Yes (DOT 1984, Guide 18)
Ingestion: Yes (DOT 1984, Guide 18)
Health Hazards (Acute, Delayed, and Chronic): It is a hazardous compound
which can cause damage to the lungs and liver (Sax 1984, p. 1551).
Medical Conditions Generally Aggravated by Exposure: Those experiencing
dermatitis, chronic bronchitis, or any form of skin allergy or respiratory
tract infection are at a greater risk (*Friberg 1979).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Extremely flammable (DOT 1984, Guide 18)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Let tank car, tank truck, or storage tank burn
unless leak can be stopped. Small fires: dry chemical or carbon dioxide.
Large fires: water spray, fog, or foam (DOT 1984, Guide 18).
Special Fire Fighting Procedures: Isolate for 1/2 mile in all directions
if tank car or truck is involved in fire. Stay upwind; keep out of low
areas. Withdraw immediately in case of rising sound from venting safety
device or any discoloration of tank due to fire. Wear self-contained
breathing apparatus and full protective clothing. Cool containers that are
exposed to flames with water until well after the fire is out (DOT 1984,
Guide 18).
Unusual Fire and Explosion Hazards: It is extremely flammable; may be
ignited by heat, sparks, or flames. Vapors may travel to a source of
ignition and flash back. Container may explode in heat of fire (DOT 1984,
Guide 18). It is dangerous and forms explosive mixtures with air (*Sax
1979).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 7783-07-5
Page 3 of 4
HYDROGEN SELENIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: It should be stored out of the direct rays of
the sun (*Sax 1975). Keep away from heat and flames (Sax 1984, p.
1552).
Incompatibility (Materials to Avoid): Incompatible with acid, water,
halogenated hydrocarbons, oxidizers, hydrogen peroxide, and nitric acid
(*Sax 1979; NIOSH/OSHA 1978, p. 112).
Hazardous Decomposition or Byproducts: It can decompose into toxic fumes
(*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
It is an intermediate for metal selenides and organoselenium compounds.
Also used in doping gas for preparation of semiconductor materials (*SRI).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition sources; no flares, smoking, or flames in hazard area.
Stop leak if you can do it without risk. Use water spray to reduce vapors;
isolate area until gas has dispersed (DOT 1984, Guide 18).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms may include garlic odor on
breath, dizziness, nausea, vomiting, labored breathing, bluing of skin,
pulmonary edema, metallic taste, coughing, nasal secretion, pain in the
chest, difficulty in breathing, irritation of the eyes, irritation of the
respiratory tract resulting in bronchitis and conjunctivitis (*Browning
-------
CAS Registry Number: 7783-07-5
Page 4 of 4
HYDROGEN SELENIDE
SECTION IX (continued)
1969, *Hamilton 1974; *Patty 1963, *Merck 1976, *Clayton and Clayton
1981-82).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed; keep victim under observation (DOT 1984, Guide 18).
-------
CAS Registry Number: 7783-60-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SULFUR TETRAFLUORIDE
CAS Registry Number: 7783-60-0
Synonyms (SANSS 1983 Synonyms): Sulfur Fluoride (SF4), (T-4)-;
Tetrafluorosulfurane
Chemical Formula: SF4
Molecular Weight: 108.06
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCiow inhalation
(rat) 0.08 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -40°F, -40°C (Weast 1979, p. B-131)
Specific Gravity (H2O=1): Liquid at -108°F, -78°C: 1.95; Solid at
-297°F, -183°C: 2.349 (Merck 1983, p. 1289)
Vapor Pressure (mmHg): Not Found
Melting Point: -191°F, -124°C (Weast 1979, p. B-131)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (Weast 1979, p. B-131)
Appearance and Odor: Gas (Weast 1979, p. B-131); colorless (Merck 1983,
p. 1289).
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CAS Registry Number: 7783-60-0
Page 2 of 4
SULFUR TETRAFLUORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Fluorides) TWA 2.5 mg/m8, as fluoride (NIOSH 1987, p. 126)
ACGIH TLV: Ceiling 0.1 ppm (0.4 mg/ms) (AGCIH 1986-87, p. 30)
IDLH: Not Found
Other Limits Recommended: (Fluorides) NIOSH: 2.5 mg/ms 10-hour TWA, as
fluorine (NIOSH 1987, p. 126). IDLH for fluorides 500 mg/ms (NIOSH 1987,
p. 126).
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 983)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by inhalation; it is a strong irritant to eyes and mucous membranes
(Hawley 1981, p. 983). Poisonous; may be fatal if inhaled. Contact may
cause burns to skin and eyes. Contact with liquid may cause frostbite (DOT
1984, Guide 15).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is non-combustible (Hawley 1981, p.
983). Small fires: dry chemical or carbon dioxide. Large fires: water
spray, fog or foam. Do not get water inside container. Move container
from fire area if you can do so without risk. Stay away from ends of
tanks. Spray cooling water on containers that are exposed to flames until
well after fire is out. Isolate area until gas has dispersed (DOT 1984,
Guide 15).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and full protective clothing. Evacuate area endangered by gas
(DOT 1984, Guide 15).
Unusual Fire and Explosion Hazards: Container may explode in heat of fire
(DOT 1984, Guide 15).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 7783-60-0
Page 3 of 4
SULFUR TETRAFLUORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, thermostable to 600°C (Merck 1983, p. 1289)
Conditions to Avoid: Reacts violently with water (Merck 1983, p.
1289)
Incompatibility (Materials to Avoid): Reacts violently with water. It is
decomposed by concentrated sulfuric acid (Merck 1983, p. 1289).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluorides and sulfur oxides (Sax 1984, p. 2492).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a selective fluorinating agent (Merck 1983, p.
1289).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapors (see Section III above). Stop leak if you can
do so without risk. Do not put water on leak or spill area. Small spills:
flush area with flooding amounts of water. Large spills: dike far ahead of
spill for later disposal. Do not get water inside container. Isolate
area until gas has dispersed (DOT 1984, Guide 15).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
-------
CAS Registry Number: 7783-60-0
Page 4 of 4
SULFUR TETRAFLUORIDE
SECTION IX (continued)
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed; keep victim under observation (DOT 1984, Guide 15).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians Desk Reference 1985
Gilman 1985
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CAS Registry Number: 7783-70-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ANTIMONY PENTAFLUORIDE
CAS Registry Number: 7783-70-2
Synonyms: Antimony Fluoride; Antimony (V) Fluoride; Antimony (V)
Pentafluoride; Pentafluoroantimony
Chemical Formula: SbF5
Molecular Weight: 216.76
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.27 mg/L (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Antimony Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 286°F, 141°C (*Merck 1976)
Specific Gravity (H2O=1): 3.097 at 25.8°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: 47°F, 8.3°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble (*Weast 1979)
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CAS Registry Number: 7783-70-2
Page 2 of 4
ANTIMONY PENTAFLUORIDE
SECTION II (continued)
Appearance and Odor: Oily, colorless liquid (*NFPA 1978); sharp odor
(*CHRIS 1978).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Antimony and compounds) TWA 0.5 mg/ms, as antimony (NIOSH 1987,
P. 52)
ACGIH TLV: (Antimony and compounds) TWA 0.5 mg/ms, as antimony (ACGIH
1986-87, p. 10)
IDLH: Not Found
Other Limits Recommended: IDLH for Antimony and Compounds: 80 mg/m8
(NIOSH/OSHA 1978, p. 48). (Antimony and compounds) NIOSH: 0.5 mg/ms
10-hour TWA (NIOSH 1987, p. 52).
Routes of Entry: Inhalation: Yes (Weiss 1980, p. 121)
Skin: Yes (*NFPA 1975)
Ingestion: Yes (Gosselin 1984, p. IM33)
Health Hazards (Acute, Delayed, and Chronic): The compound is irritating
to eyes, skin, and lungs (*NFPA 1975). Contact with eyes or skin causes
severe burns (*CHRIS 1978). The compound is extremely toxic with a
probable oral lethal dose of 5-50 mg/kg or between 7 drops and teaspoonf ul
for a 150 pound person (antimony salts) (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not flammable (Weiss 1980, p. 121)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not use water or foam on fire or on adjacent
fires; extinguish with dry chemicals or carbon dioxide (Weiss 1980, p.
121).
Special Fire Fighting Procedures: Wear full protective clothing (*NFPA
1978) and acid-gas-type canister mask (*CHRIS 1978). Move container from
fire area. Spray cooling water on containers that are exposed to flames
until well after fire is out (DOT 1984, Guide 59). Reacts violently with
water (*Merck 1976).
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CAS Registry Number: 7783-70-2
Page 3 of 4
ANTIMONY PENTAFLUORIDE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Reacts violently with water (*Merck
1976) to form poisonous hydrogen fluoride fumes. If confined and wet can
cause explosion. May cause fire in contact with combustible material
(Weiss 1980, p. 121).
NFPA Flammability Rating: 0
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 121)
Conditions to Avoid: If confined and wet, can cause explosion. May
cause fire in contact with combustible material (Weiss 1980, p. 121).
Incompatibility (Materials to Avoid): Reacts violently with water (*Merck
1976).
Hazardous Decomposition or Byproducts: When heated with water, it emits
poisonous hydrogen fluoride fumes (Weiss 1980, p. 121).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 121)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Fluorination of organic compounds (*Merck 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Flood spills with large volumes of water (*NFPA 1978). Reacts violently
with water (*Merck 1976). Do not touch spilled material; stop leak if you
can do so without risk. Use water spray to reduce vapors. Absorb spills
with noncombustible absorbent material. For large spills dike far ahead
(DOT 1984, Guide 59).
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CAS Registry Number: 7783-70-2
Page 4 of 4
ANTIMONY PENTAFLUORIDE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Ingestion causes vomiting and severe
burns of mouth and throat. Overexposure by any route can cause bloody
stools, slow pulse, low blood pressure, coma, convulsions, and cardiac
arrest (*CHRIS 1978).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration; if
difficult breathing, give oxygen. In case of contact with material,
immediately flush with running water for at least 15 minutes. Remove and
isolate contaminated clothing and shoes at the site. Effects may be
delayed; keep victim under observation (DOT 1984, Guide 59).
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CAS Registry Number: 7783-80-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TELLURIUM HEXAFLUORIDE
CAS Registry Number: 7783-80-4
Synonyms: Tellurium Fluoride (TeF6); Tellurium Fluoride (TeF6), (OC-6-11)-
Chemical Formula: TeF6
Molecular Weight: 241.61
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCjow inhalation
(rabbit, guinea pig) 0.049 mg/liter/8 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 95.91°F, 35.5°C (*Weast 1979)
Specific Gravity (H2O=1): 2.499 at -10°C (*Merck 1976)
Vapor Pressure (mmHg): Greater than 760 (NIOSH/OSHA 1978, p. 172)
Melting Point: -35.7°F, -37.6°C (*Merck 1976)
Vapor Density (AIR=1): Greater than 1 (NIOSH/OSHA 1978, p. 172)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes (Weast 1979, p. B-132)
Appearance and Odor: Colorless gas; repulsive odor (*Merck 1976).
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CAS Registry Number: 7783-80-4
Page 2 of 4
TELLURIUM HEXAFLUORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.02 ppm (0.2 mg/ms), as tellurium (NIOSH 1987, p. 216)
ACGIH TLV: TWA 0.02 ppm (0.2 mg/ms), as tellurium (*ACGIH 1980)
IDLH: 1 ppm (NIOSH/OSHA 1978, p. 172)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Sax 1979)
Health Hazards (Acute, Delayed, and Chronic): Capable of causing death or
- permanent injury. Acute — the material is highly toxic by inhalation
exposure and a strong irritant to skin, eyes, the lungs, the throat, and
stomach (*Sax 1979). Death can occur from filling of the lungs with fluid
(pulmonary edema) or from asphyxiation due to spasm of the throat (larynx)
or bronchi (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Those with impaired
pulmonary function, especially obstructive airway diseases are at a greater
risk (*NIOSH/OSHA 1981).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is not combustible (NIOSH/OSHA 1978,
p. 172). Small fires: dry chemical or carbon dioxide. Large fires:
water spray, fog or foam (DOT 1984, Guide 15).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and full protective clothing. Do not get water inside container.
Move container from fire area if you can do so without risk. Stay away
from ends of tanks. Spray cooling water on containers that are exposed to
flames until well after fire is out. Isolate area until gas has dispersed
(DOT 1984, Guide 15).
Unusual Fire and Explosion Hazards: Container may explode in heat of fire
(DOT 1984, Guide 15). When heated to decomposition, it emits very toxic
fumes of fluoride and tellurium (Sax 1984, p. 2502).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 7783-80-4
Page 3 of 4
TELLURIUM HEXAFLUORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposes in water, acid, and alkali (*Weast
1979).
Incompatibility (Materials to Avoid): None hazardous (NIOSH/OSHA 1978, p.
172).
Hazardous Decomposition or Byproducts: Toxic gases and vapors such as
hydrogen fluoride may be released when tellurium hexafluoride decomposes
(*NIOSH/OSHA 1981). When decomposed, toxic fumes of fluoride and tellurium
are released (Sax 1984, p. 2502).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of leak to disperse vapors. Stop the flow of the leak.
Remove the leaking container to a safe place in the open air and allow the
leak to disperse (*NIOSH/OSHA 1981). Use water spray to reduce vapor but
do not put water on leak or spill area. Small spills: flush area
with flooding amounts of water. Large spills: dike far ahead of spill for
later disposal. Do not get water inside container. Isolate area until
gas has dispersed (DOT 1984, Guide 15).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 7783-80-4
Page 4 of 4
TELLURIUM HEXAFLUORIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7783-80-4
Page 1 of 3
Emergency First Aid Treatment Guide
for
TELLURIUM HEXAFLUORIDE
(7783-80-4)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas.
Odor - Garliclike, repulsive.
Material to Avoid - Water (except for use in emergency life support).
Caution: Avoid sources of heat including fire; hydrogen fluoride and tellurium
fumes will be liberated when heated to decomposition. Tellurium hexafluoride
will emit toxic fumes of hydrogen fluoride gas upon decomposition in water.
Other Name - Tellurium fluoride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Tellurium Hexafluoride Exposure:
Signs and symptoms of acute exposure to tellurium hexafluoride may include
drowsiness, malaise, lassitude, weakness, and dizziness. A metallic taste,
garlicky breath, and profuse sweating may be noted. Kidney damage, liver
injury, and pulmonary effects such as pulmonary edema and bronchial spasms may
also occur. Gastrointestinal effects may include nausea, vomiting, anorexia,
and constipation. Dermal exposure may result in dermatitis (red, inflamed
skin).
-------
EFATG
CAS Registry Number: 7783-80-4
Page 2 of 3
TELLURIUM HEXAFLUORIDE
Emergency Life-Support Procedures:
Acute exposure to tellurium hexafluoride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to tellurium hexafluoride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to tellurium hexafluoride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
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EFATG
CAS Registry Number: 7783-80-4
Page 3 of 3
TELLURIUM HEXAFLUORIDE
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support. Humidified oxygen is preferred.
2. IMMEDIATELY give the victims milk or water to dilute the hydrofluoric
acid: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to
12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Milk or water should be given only if victims are conscious and alert.
3. DO NOT induce vomiting.
4. Milk of Magnesia should be administered if victims are conscious and
alert. Use 2.5 mL (1/2 tsp) for children up to 1 year old, 5 mL (1 tsp)
for children 1 to 12 years old, and 10 mL (2 tsp) for adults. Do not
exceed 15 mL (3 tsp or 1 tbsp).
5. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
6. Activated charcoal is of no value.
7. Repeat the administration of water or milk to conscious and alert victims.
Use quantities listed abov^ (see No. 2).
8. Transport to a health care facility.
-------
CAS Registry Number: 7784-34-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ARSENOUS TRICHLORIDE
CAS Registry Number: 7784-34-1
Synonyms: Arsenic Trichloride; Arsenic Butter; Arsenic Chloride; Arsenic
(III) Chloride; Arsenic (III) Trichloride; Arsenious Chloride; Arsenous
Chloride; Butter of Arsenic; Caustic Arsenic Chloride; Caustic Oil of Arsenic;
Fuming Liquid Arsenic; Trichloroarsine
Chemical Formula: As'Cl3
Molecular Weight: 181.28
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCjow inhalation
(cat) 0.1 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 5000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 266.38°F, 130.21°C (*Merck 1983)
Specific Gravity (H2O=1): 2.1497 at 25°C/4°C (*Merck 1983)
Vapor Pressure (mmHg): 10 at 23.5°C (*Patty 1963)
Melting Point: 3.2°F, -16°C (*Merck 1983)
Vapor Density (AIR=1): 6.25 (*Clayton and Clayton 1981-82)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: One mole in 9 moles (*Merck 1983)
-------
CAS Registry Number: 7784-34-1
Page 2 of 4
ARSENOUS TRICHLORIDE
SECTION II (continued)
Appearance and Odor: Yellowish oily liquid or needle-shaped crystals
(*Patty 1963); acrid odor (*CHRIS 1978).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/m3, as arsenic (NIOSH 1987,
P. 54)
ACGIH TLV: (Arsenic and soluble compounds) TWA 0.2 mg/ms, as arsenic
(ACGIH 1986-87, p. 10)
IDLH: Not Found
Other Limits Recommended: (Arsenic and compounds) NIOSH: 0.002 mg/ms
15-minute ceiling (NIOSH 1987, p. 54). (Arsenic and compounds) NIOSH
occupational carcinogen (NIOSH 1987, p. 54).
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (Gosselin 1984, p. 111-42)
Ingestion: Yes (Gosselin 1984, p. 111-42)
Health Hazards (Acute, Delayed, and Chronic): It can cause death. In
acute exposures, it is extremely toxic and caustic, owing not only to the
poisonous nature of arsenic, but also to the release of hydrochloric acid
in the presence of water (*Grant 1974). Exposure to the skin causes local
irritation and blisters. Inhalation or ingestion causes hemorrhagic
gastroenteritis resulting in loss of fluids and electrolytes, collapse,
shock and death (Gosselin 1984, p. 111-42). Chronic poisoning can lead to
peripheral nerve damage, skin conditions, liver damage (*Sax 1975, *Merck
1976); and it has been implicated in the induction of skin and lung cancer
(Gosselin 1984, p. HI-42, Oilman 1980). The fatal human dose is 70-180 mg
depending on the weight of the victim (Weiss 1980, p. 128).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is not flammable (*NFPA 1978).
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and special protective clothing. Move container from fire area
if you can do so without risk. Fight fire from maximum distance. Dike
-------
CAS Registry Number: 7784-34-1
Page 3 of 4
ARSENOUS TRICHLORIDE
SECTION IV (continued)
fire control water for later disposal; do not scatter the material (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: When in contact with active metals
such as arsenic, iron, aluminum, zinc, or when heated to decomposition, it
emits highly toxic fumes of arsenic (*Sax 1975). Upon contact with water
hydrogen chloride is produced (*NFPA 1978). Water causes it to decompose
to yield arsenic acid and hydrochloric acid (Student 1981, p. 49).
NFPA Flammability Rating: 0
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 128)
Conditions to Avoid: Air, ultraviolet light (*Hawley 1981)
Incompatibility (Materials to Avoid): Active metals such as arsenic,
iron, aluminum, zinc (*Sax 1975); decomposed by water to form arsenic
hydroxide and hydrogen chloride (Merck 1983, p. 117).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of arsenic. Contact with water produces hydrogen
chloride (*Sax 1975).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 128)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Ceramics industry; synthesis of chlorine - containing arsenicals (*Merck
1983); chemical intermediate for arsenic insecticides and arsenic
Pharmaceuticals (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Remove and isolate contaminated clothing at the site. Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
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CAS Registry Number: 7784-34-1
Page 4 of 4
ARSENOUS TRICHLORIDE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED
Viton/Neoprene POOR/LIMITED
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7784-34-1
Page 1 of 4
Emergency First Aid Treatment Guide
for
ARSENOUS TRICHLORIDE
(7784-34-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Pale yellow, oily liquid or needle-shaped crystals below
16 degrees C (3 degrees F).
Odor - Sharp, biting.
Commercial Form - Liquid in glass bottles or 20- and 55-gallon drums.
Uses - Ceramic production, chemical intermediate for pesticides and
Pharmaceuticals.
Materials to Avoid - Water (except for use in emergency life support).
Caution: Contact with water will result in the formation of toxic hydrogen
chloride gas.
Other Names - Arsenic chloride, arsenious chloride, arsenous chloride, butter
of arsenic, caustic arsenic chloride, fuming liquid arsenic, trichloroarsine.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, KC1,
dopamine, norepinephrine, sodium bicarbonate, dimercaprol, penicillamine.
-------
EFATG
CAS Registry Number: 7784-34-1
Page 2 of 4
ARSENOUS TRICHLORIDE
Signs and Symptoms of Acute Arsenous Trichloride Exposure:
Warning: Effects usually appear within 30 minutes of exposure but may be
delayed for several hours. Caution is advised.
Dehydration, intense thirst, vomiting, severe abdominal pain, and diarrhea are
among the first signs and symptoms of acute arsenous trichloride exposure.
Hypotension (low blood pressure) and tachycardia (rapid heart rate) are common.
Headache, conjunctivitis (red, inflamed eyes), runny nose, and lacrimation
(tearing) may also be seen. Garlic odor to the breath and feces may be noted.
Cardiovascular signs include shock, ventricular fibrillation, tachycardia, and
other cardiac abnormalities. Pulmonary edema may occur. Altered mental
status, seizures, and delirium are further complications of acute arsenous
trichloride exposure. Intense muscular cramping is common. Contact with
airborne dust can result in the release of hydrochloric acid and is generally
accompanied by irritation of exposed skin, eyes, and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to arsenous trichloride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to arsenous trichloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 7784-34-1
Page 3 of 4
ARSENOUS TRICHLORIDE
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to arsenous trichloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
ar ificial respiration. If breathing is labored, administer oxygen or
otiser respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. DO NOT induce vomiting.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
5. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to
3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
-------
EFATG
CAS Registry Number: 7784-34-1
Page 4 of 4
ARSENOUS TRICHLORIDE
6. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
7. RUSH to a health care facility.
-------
CAS Registry Number: 7784-42-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ARSINE
CAS Registry Number: 7784-42-1
Synonyms: Arsenic Hydride; Arsenic Trihydride; Arseniuretted Hydrogen;
Arsenous Hydride; Hydrogen Arsenide
Chemical Formula: AsH3
Molecular Weight: 77.93
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCjow inhalation
(mouse) 0.07 mg/liter/3 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -80.4°F, -62.5°C (*Merck 1983)
Specific Gravity (H2O=1): 1.689 at 185°F, 84.9°C (liquid)
(*Weast 1979) (Patty, 1981, p. 1520)
Vapor Pressure (mmHg): Greater than 1 atm (NIOSH/OSHA 1978, p. 48)
Melting Point: -179°F, -117°C (*Merck 1983)
Vapor Density (AIR=1): 2.66 (*Sax 1986), 2.695 (Weast 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 20 ml/100 ml at 68°F, 20°C (*Clayton and Clayton
1981-1982)
Appearance and Odor: Colorless gas; disagreeable garlic odor (*Merck
1983).
-------
CAS Registry Number: 7784-42-1
Page 2 of 4
ARSINE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.05 ppm, (0.2 mg/ms) (NIOSH 1987, p. 54)
ACGIH TLV: TWA 0.05 ppm, (0.2 mg/ms) (*ACGIH 1983)
IDLH: 6 ppm (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: NIOSH: 0.002 mg/ms 15-minute ceiling (NIOSH
1987, p. 54). NIOSH occupational carcinogen (NIOSH 1987, p. 54). EEGL
1.0 ppm (60 minutes) (NRC 1984a, pp. 35-40)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by inhalation; a very short exposure to small quantities may cause
death or permanent injury (Sax 1984, p. 323). Arsine is the most powerful
hemolytic poison encountered in industry (*Hamilton 1974).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Extremely flammable; may be ignited by heat, sparks, or
flames (*DOT 1984)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Let small fires burn. Use water spray, fog, or
foam for large fires. For massive fire in cargo area use unmanned hose
holder or monitor nozzles; if this is impossible, withdraw from area and
let fire burn (*DOT 1984).
Special Fire Fighting Procedures: Cool containers that are exposed to
flames with water from the side until well after fire is out. Isolate for
1/2 mile in all directions if tank car or truck is involved in fire (*DOT
1984).
Unusual Fire and Explosion Hazards: Vapors may travel to a source of
ignition and flash back. Container may explode in heat of fire (*DOT
1984). When heated to decomposition, emits highly toxic fumes (*Sax 1979).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1983)
Stable:
Conditions to Avoid: On exposure to light, moist arsine decomposes
-------
CAS Registry Number: 7784-42-1
Page 3 of 4
ARSINE
SECTION V (continued)
quickly, depositing shiny black arsenic (*Merck 1983).
Incompatibility (Materials to Avoid): Can react vigorously with oxidizing
materials. May explode when exposed to chlorine, nitric acid, or potassium
plus ammonia (Sax 1984, p. 324; NIOSH/OSHA 1978, p. 48).
Hazardous Decomposition or Byproducts: When heated to decomposition,
emits highly toxic fumes (Sax 1984, p. 324).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used in the manufacture of electronic components. It may
be used in organic synthesis and as a poison gas for military purposes
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
No flares, smoking, or flames in area. Use water spray to reduce vapors.
Isolate area until arsine gas has dispersed. Stay upwind; keep out of low
areas (*DOT 1984). There is a high potential for generation of arsine
gas when inorganic arsenic is exposed to freshly-formed molecular hydrogen
(*Blackwell 1979).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 7784-42-1
Page 4 of 4
ARSINE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7784-42-1
Page 1 of 3
Emergency First Aid Treatment Guide
for
ARSINE
(7784-42-1)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas.
Odor - Disagreeable, garliclike.
Commercial Form - 99% pure or in mixture with other gases in steel cylinders.
Uses - Organic synthesis, manufacture of semi-conductors, chemical warfare
agent.
Materials to Avoid - Oxidizers, water (except for use in emergency life
support).
Caution: Extremely flammable. Avoid sources of ignition.
Other Names - Arsenic hydride, arsenic trihydride, arseniuretted hydrogen,
arsenous hydride, hydrogen arsenide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, normal saline, D5W, Ringer's
lactate, dopamine, dimercaprol (BAL).
-------
EFATG
CAS Registry Number: 7784-42-1
Page 2 of 3
ARSINE
Signs and Symptoms of Acute Arsine Exposure:
Warning: Effects usually appear within 30 to 60 minutes, but may be delayed
for several hours. Caution is advised.
Note: Arsine is the most powerful hemolytic poison encountered in industry.
Acute arsine exposure may be fatal. Headache and a garlicky odor of the breath
may be the first signs and symptoms noted following acute exposure to arsine.
Victims may experience hypotension (low blood pressure), generalized weakness,
and muscle cramping. Gastrointestinal effects include nausea, vomiting,
anorexia, and abdominal pain. Urine may be colored red or green, and the
volume may be reduced. Arsine is corrosive to the skin, eyes, and mucous
membranes. Severe exposure may result in cardiac abnormalities.
Emergency Life-Support Procedures:
Acute exposure to arsine may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Victims must be transported to a health
care facility as quickly as possible. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to arsine.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to arsine.
-------
EFATG
CAS Registry Number: 7784-42-1
Page 3 of 3
ARSINE
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Remove contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
6. THOROUGHLY wash exposed skin areas with water.
7. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
Ingestion Exposure: No information is available.
-------
CAS Registry Number: 7784-46-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM ARSENITE
CAS Registry Number: 7784-46-5
Synonyms: Arsenenous Acid, Sodium Salt; Arsenious Acid, Monosodium Salt;
Atlas 'A'; Chem Pels C; Chem-Sen 56; Kill-All; Penite; Prodalumnol; Prodalumnol
Double; Sodium Metaarsenite; Arsenious Acid, Sodium Salt
Chemical Formula: NaAsO2 (Merck 1983, p. 1230)
Molecular Weight: 129.91 (Sax 1984, p. 2412)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDgo oral
(mammal) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1000 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.87 (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble (*Merck 1983).
Appearance and Odor: White or grayish-white powder (*Merck 1983) with a
salty taste (*White-Stevens 1971)
-------
CAS Registry Number: 7784-46-5
Page 2 of 4
SODIUM ARSENITE
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: (Arsenic and soluble compounds) TWA 0.01 mg/m8, as arsenic
(NIOSH 1987, p. 54)
ACGIH TLV: (Arsenic and soluble compounds) TWA 0.2 mg/ms, as arsenic
(ACGIH 1985, p. 10)
IDLH: Not Found
Other Limits Recommended: (Arsenic and soluble compounds) NIOSH: 0.002
mg/m3, 15-minute ceiling, as arsenic (NIOSH 1987, p. 54); (Arsenic and
soluble compounds) NIOSH occupational carcinogen (NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (Sax 1984, p. 2412)
Ingestion: Yes (Sax 1984, p. 2412)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic: probable
oral lethal dose (human) 5-50 mg/kg, between 7 drops and one teaspoon for
70 kg person (150 Ib.) (*Gosselin 1976). Poisonous if swallowed or inhaled
(*DOT 1984). Human suspected carcinogen (Sax 1984, p. 2412).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Keep unnecessary people away; stay
upwind; keep out of low areas. Wear self-contained breathing apparatus and
full protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Slowly converted in solution to arsenates by
atmospheric oxygen; in dry state it is decomposed by carbon dioxide
(*IARC 1972-1985).
-------
CAS Registry Number: 7784-46-5
Page 3 of 4
SODIUM ARSENITE
<«
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated it emits toxic fumes
of arsenic and sodium oxide (Sax 1984, p. 2412).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
Technical grade is 90-95% pure (Merck 1983, p. 1230). Commercially 95-98
percent pure (Sax 1984, p. 2412). The material is used in manufacturing of
arsenical soap for use on skin; treating vines against certain scale
diseases (Merck 1983, p. 1230); wood preservation (*IARC 1972-1985);
reagent in preparation of methylene iodide; corrosion inhibitor (*SRI); and
herbicidal and pesticidal purposes (*IARC 1972-1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do so without risk.
Absorb small spills with sand or other noncombustible absorbent material,
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 7784-46-5
Page 4 of 4
SODIUM ARSENITE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 7784-46-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
SODIUM ARSENITE
(7784-46-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White to gray powder.
Odor - None.
i
Commercial Forms - 95 to 98% pure powder; 4, 6, 8, or 9.5% pure solution.
Uses - Herbicide, acaricide, corrosion inhibitor, textile drying, manufacture
of arsenical soaps and wood preservatives.
Caution: Avoid sources of heat including fire. Sodium arsenite will emit
toxic arsenic fumes when heated to decomposition.
Other Names - Arseneous acid, sodium salt; Atlas 'A'; Penite; Prodalumnol;
Sodanit; sodium meta-arsenite.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, activated charcoal, saline
cathartic or sorbitol, normal saline, D5W, Ringer's lactate, dimercaprol (BAL),
penicillamine, morphine.
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EFATG
CAS Registry Number: 7784-46-5
Page 2 of 3
SODIUM ARSENITE
Signs and Symptoms of Acute Sodium Arsenite Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
Signs and symptoms of acute exposure to sodium arsenite may be severe and
include cough, dyspnea (shortness of breath), hypotension (low blood pressure),
and chest pain. Gastrointestinal effects include difficulty swallowing,
intense thirst, generalized abdominal pain, vomiting, and painful diarrhea;
blood may be noted in the vomitus and feces. A weak pulse, cyanosis (blue tint
to the skin and mucous membranes), and cold extremities may also be observed.
Neurological effects include giddiness, delirium, mania, stupor, weakness,
headache, dizziness, and fainting. Convulsions, paralysis, and coma may occur.
Sodium arsenite may irritate or burn the skin, eyes, and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to sodium arsenite may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to sodium arsenite.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to sodium arsenite.
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EFATG
CAS Registry Number: 7784-46-5
Page 3 of 3
SODIUM ARSENITE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 7786-34-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MEVINPHOS
CAS Registry Number: 7786-34-7
Synonyms: Crotonic Acid, 3-Hydroxy-, Methyl Ester, Dimethyl Phosphate, (E)-;
Apavinphos; l-Methoxycarbonyl-l-propen-2-yl Dimethyl Phosphate; 2-Butenoic
Acid, 3-((Dimethoxyphosphinyl)oxy)-, Methyl Ester; 2-Carbomethoxy-
1-Methylvinyl Dimethyl Phosphate; l-Carbomethoxy-l-Propen-2-yl Dimethyl
Phosphate; 2-Methoxycarbonyl-l-Methylvinyl Dimethyl Phosphate;
3-Hydroxycrotonic Acid Methyl Ester Dimethyl Phosphate;
3-[(Dimethoxyphosphinyl)oxy]-2-Butenoic Acid Methyl Ester; Alpha-2-
Carbomethoxy-1-Methylvinyl Dimethyl Phosphate; Cis-2-Methoxycarbonyl-l-
Methylvinyl Dimethylphosphate; Cis-Phosdrin; CMDP; Compound 2046; Crotonic
Acid, 3-Hydroxy-, Methyl Ester, Dimethyl Phosphate; Dimethyl
(l-Methoxycarboxypropen-2-yl) Phosphate; Dimethyl 2-Methoxycarbonyl-
1-Methylvinyl Phosphate; Dimethyl Methoxycarbonylpropenyl Phosphate; Dimethyl
Phosphate of Methyl 3-Hydroxy-cis-Crotonate; Dimethyl-1-Carbomethoxy-1-Propen-
2-yl Phosphate; Duraphos; ENT 22,374; ENT 22374; Fosdrin; Gesfid; Gestid;
Meniphos; Menite; Methyl 3-(Dimethoxyphosphinyloxy)Crotonate; O,O-Dimethyl
l-Carbomethoxy-l-Propen-2-yl Phosphate; O,O-Dimethyl O-(l-Methyl-2-
Carboxyvinyl) Phosphate; OS-2046; PD 5; Phosdrin; Phosfene; Phosphoric Acid,
(l-Methoxycarboxypropen-2-yl) Dimethyl Ester; Phosphoric Acid, Dimethyl Ester,
Ester With Methyl 3-Hydroxycrotonate
Chemical Formula: C7H13O6P
Molecular Weight: 224.17
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCBO inhalation
(rat) 0.128 mg/liter/hour (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 223-226°F, 106-107.5°C at 1 mmHg (*Merck 1983)
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CAS Registry Number: 7786-34-7
Page 2 of 4
MEVINPHOS
SECTION II (continued)
Specific Gravity (H2O=1): 1.25 at 20°C (*Merck 1983)
Vapor Pressure (mmHg): 0.0029 at 70°F (*Spencer 1982)
Melting Point: cis isomer 70°F, 21°C; trans isomer 44.4°F, 6.9°C (Hayes
1982, p. 356; *Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1983)
Appearance and Odor: Pale yellow to orange liquid (*Spencer 1982), with a
weak odor (NIOSH/OSHA 1978, p. 154)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 0.1 mg/ms (NIOSH/OSHA 1978, p. 154)
ACGIH TLV: TWA 0.01 ppm (0.1 mg/ms) (skin); STEL 0.03 ppm (0.3 mg/ms)
(skin) (ACGIH 1986-87)
IDLH: 40 mg/ms (NIOSH/OSHA 1978, p. 154)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Gosselin 1984)
Skin: Yes (*Gosselin 1984)
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is super
toxic; the probable oral lethal dose for humans is less than 5 mg/kg, or a
taste (less than 7 drops) for a 150-lb. person. It has direct and
immediate effects whether it is swallowed, inhaled, or absorbed through the
skin (*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 175°F (OC) (*Clayton and Clayton 1981-82)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: use dry chemical, carbon dioxide,
water spray or foam. Large fires: use water spray, fog or foam. Fight
fire from maximum distance. Dike fire control water for later disposal
(*DOT 1984).
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CAS Registry Number: 7786-34-7
Page 3 of 4
MEVINPHOS
SECTION IV (continued)
Special Fire Fighting Procedures: Isolate hazard area, stay upwind;
ventilate closed spaces before entering, wear protective clothing and
positive breathing apparatus. Remove and isolate contaminated clothing
(*DOT 1984).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases. Runoff from fire control may give off poisonous gases and
also cause pollution (*DOT 1984).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1982)
Conditions to Avoid: Temperatures above 25-30°C, sources of heat,
fire, free flames or spark-generating equipment (*Farm Chemicals .
Handbook, 1984)
Incompatibility (Materials to Avoid): Strong oxidizers (*NIOSH/OSHA 1978)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of phosphorus oxides (Sax 1984, p. 639)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to \void: Not Found
SECTION VI - USE INFORMATION
Used as an insecticide and acaricide on vegetables, alfalfa, deciduous
fruits and nuts (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material (see Section III above). In case of spills,
stay upwind; keep out of low areas. Ventilate closed areas before entering
them. Use water spray to reduce vapors (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7786-34-7
Page 4 of 4
MEVINPHOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
dizziness, runny nose, tightness in the chest, blurring and dimming of
vision, slurrying of speech, twitching of muscles, mental confusion,
disorientation, difficulty breathing, bluing of skin, convulsions, coma,
and death (*Gosselin 1984)
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 7791-12-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THALLOUS CHLORIDE
CAS Registry Number: 7791-12-0
Synonyms: Thallium Chloride; Thallium Chloride (T1C1); Thallium Monochloride;
Thallium (1+) Chloride; Thallium (I) Chloride
Chemical Formula: T1C1
Molecular Weight: 239.82
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 24 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Thallium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 1328°F, 720°C (*Weast 1979)
Specific Gravity (H2O=1): 7.0 (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: 806°F, 430°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in 260 parts cold water (*Merck 1976)
Appearance and Odor: White, crystalline powder (*Merck 1976); becomes
violet on exposure to light (*Hawley 1977).
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CAS Registry Number: 7791-12-0
Page 2 of 4
THALLOUS CHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Soluble Thallium Compounds), 0.1 mg/m8, as Thallium (skin) (OSHA
1984, p. 663)
ACGIH TLV: (Soluble Thallium Compounds), TWA 0.1 mg/m3, as Thallium (skin)
(ACGIH 1986-87, p. 31)
IDLH: Not Found
Other Limits Recommended: IDLH for soluble thallium compounds 20 mg/m3, as
thallium (NIOSH 1987, p. 224). Occupational exposure to thallium compounds
recommended standard 20 mg/m3 (NIOSH/OSHA 1978, p. 178).
Routes of Entry: Inhalation: Yes (*Venugopal 1978)
Skin: Yes (*Venugopal 1978)
Ingestion: Yes (*Venugopal 1978)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific — Thallium
Salts) Poisonous if swallowed. Inhalation of dust is poisonous (DOT 1984,
Guide 53).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Thallium Salts) Small fires:
dry chemical, carbon dioxide, water spray or foam. Large fires: water
spray, fog or foam (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific — Thallium Salts) Move
container from fire area if you can do so without risk (DOT 1984, Guide
53).
Unusual Fire and Explosion Hazards: (Non-Specific -- Thallium Salts)
Fire may produce irritating or poisonous gases (DOT 1984, Guide 53). When
heated to decomposition, it emits very toxic fumes of chloride and thallium
(Sax 1984, p. 2556).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
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CAS Registry Number: 7791-12-0
Page 3 of 4
THALLOUS CHLORIDE
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Thallium(I) chloride is vigorously
attacked by cold fluorine (*Bretherick 1979). A mixture of potassium and
thallous chloride produces a weak explosion on impact (*NFPA 1978).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Used as a catalyst in chlorinations (*Merck 1976) and in suntan lamps
(*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above). (Non-Specific -- Thallium Salts)
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other non-combustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 7791-12-0
Page 4 of 4
THALLOUS CHLORIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7791-12-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
THALLOUS CHLORIDE
(7791-12-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White to violet crystalline powder.
Commercial Form - Powder in glass bottles.
Uses - Suntan lamps, catalyst.
Other Names - Thallium chloride, thallium monochloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Thallous Chloride Exposure:
Warning: Effects may be delayed from hours to days. Caution is advised.
Signs and symptoms of acute exposure to thallous chloride may be severe and
include bronchitis, pneumonia, and respiratory paralysis. Tachycardia (rapid
heart rate) may occur. Victims may experience headache, delerium, dementia,
depression, psychosis, and peripheral burning sensations with severe pain.
Muscle weakness and atrophy, incoordination, choreif orm (spasmodic) movements,
convulsions, shock, and coma may also occur. Hair loss is common.
Gastrointestinal effects include increased salivation, inflammation of the oral
cavity, anorexia, vomiting (may be bloody), diarrhea (may be bloody), abdominal
pain, and constipation. Kidney damage has been reported.
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EFATG
CAS Registry Number: 7791-12-0
Page 2 of 3
THALLOUS CHLORIDE
Emergency Life-Support Procedures:
Acute exposure to thallous chloride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to thallous chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to thallous chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
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EFATG
CAS Registry Number: 7791-12-0
Page 3 of 3
THALLOUS CHLORIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of thallous chloride is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of thallous chloride may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 7791-23-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ SELENIUM OXYCHLORIDE
CAS Registry Number: 7791-23-3
Synonyms: Seleninyl Chloride; Seleninyl dichloride; Selenium chloride oxide;
Selenium oxydichloride
Chemical Formula: SeOCl2
Molecular Weight: 165.87
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDlow skin
(rabbit) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Selenium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 356°F, 180°C (*Merck 1976)
Specific Gravity (H2O=1): 2.44 at 16°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 1 at 94.6°F, 34.8°C (*Sax 1979)
Melting Point: 47.3°F, 8.5°C (*Weast 1979)
Vapor Density (AIR=1): Not found
Evaporation Rate (Butyl acetate=l): Not found
Solubility in Water: Decomposed by water into hydrochloric acid and
selenious acid (*Merck 1976).
Appearance and Odor: Nearly colorless or yellowish liquid (*Merck 1976).
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CAS Registry Number: 7791-23-3
Page 2 of 4
SELENIUM OXYCHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Selenium compounds) TWA 0.2 mg/ms, as Selenium (NIOSH 1987,
p. 206)
ACGIH TLV: (Selenium compounds) TWA 0.2 mg/ms, as Selenium (ACGIH 1986-87,
p. 29)
IDLH: (Selenium compounds) 100 mg/ms, as Selenium (NIOSH 1987, p. 206)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is very toxic
and may cause death or permanent injury after very short exposures to small
quantities (*Sax 1975). Inhalation of small quantities may be corrosive
and irritating to the respiratory tract (*Patty 1963). It can burn and
irritate the skin and eyes and cause burns when ingested (*Rumack 1975 to
Present). Long-term exposure to selenium compounds may be a cause of
amyotrophic lateral sclerosis in humans (Sax 1984, pp. 2391-92).
Medical Conditions Generally Aggravated by Exposure: Populations at
special risk include those with a history of dermatitis, chronic
bronchitis, skin allergies, respiratory tract infections, liver or kidney
disease, jaundice, or albuminuria. Women of child-bearing age are also
considered at risk (*Friberg 1979).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use dry chemical, carbon dioxide, water spray, or
foam for small fires; use water spray, fog, or foam for large fires (*DOT
1984).
Special Fire Fighting Procedures: Cool containers that are exposed to
flames with water until well after the fire is out. Stay upwind; keep out
of low areas. Wear positive pressure breathing apparatus and special
protective clothing (*DOT 1984).
Unusual Fire and Explosion Hazards: When this material is heated to
decomposition, or in contact with acids or acid fumes, highly toxic
chloride and selenium fumes are evolved (*Sax 1979).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 7791-23-3
Page 3 of 4
SELENIUM OXYCHLORIDE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1976)
Stable:
Conditions to Avoid: Water, moist air (*Merck 1976)
Incompatibility (Materials to Avoid): Decomposed by water (*Merck 1976).
Reacts violently with powdered antimony, red and white phosphorus, disilver
oxide, lead oxides, and potassium (*Bretherick 1979).
Hazardous Decomposition or Byproducts: Hydrochloric acid and selenious
acid are produced by reaction with water (*Merck 1976); toxic chloride and
selenium fumes are evolved when material is heated to decomposition (*Sax
1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
This material is used as a solvent for many substances, including metals
(*Merck 1976) and as a chlorinating agent and resin plasticizer (*Patty
1963).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Isolate hazard area. Stay upwind; keep out of low areas. Do not touch
spilled material. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike spill for later disposal (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
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CAS Registry Number: 7791-23-3
Page 4 of 4
SELENIUM OXYCHLORIDE
SECTION VIII (continued)
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation of this material may cause
garlic breath odor, nausea, vomiting, indigestion, fever, headache,
lassitude, irritability, and unstable blood pressure. Eye contact can
cause burns or irritation (*Friberg 1979). Ingestion can produce burns to
the mouth, esophogus, and stomach. Skin contact may produce severe burns
(*Rumack 1975 to Present).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing give artificial respiration. If
breathing is difficult give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin and eyes with running water for at least 15 minutes
(DOT 1984, Guide 59).
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CAS Registry Number: 7803-51-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ PHOSPHINE
CAS Registry Number: 7803-51-2
Synonyms: Hydrogen Phosphide; Celphos; Delicia; Delia; Gas-Ex-B;
Phosphoretted Hydrogen; Phosphorus Trihydride
Chemical Formula: PH3
Molecular Weight: 34.00
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.015 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -126°F, -87.7°C (*Merck 1983)
Specific Gravity (H2O=1): 0.746 at -90°C (*Weast 1979)
Vapor Pressure (mmHg): 760 at -87.5°C (Weast 1979, p. D-201)
Melting Point: -207°F, -133°C (*Merck 1983)
Vapor Density (AIR=1): 1.17 (*NFPA 1978)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (*Merck 1983); 26cc/100mL at 17°C
(Farm Chemicals Handbook 1984, p. C-47)
Appearance and Odor: Colorless gas or liquid (*Weast 1979) with a
disagreeable, fishy odor (*Grant 1974); a colorless gas with a disagreeable
garlic-like odor (Student 1981, p. 405)
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CAS Registry Number: 7803-51-2
Page 2 of 4
PHOSPHINE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.3 ppm (0.4 mg/ms) (NIOSH/OSHA 1978, p. 154)
ACGIH TLV: TWA 0.3 ppm (0.4 mg/ms) (ACGIH 1983, p. 29); STEL 1 ppm (1
mg/ms) (*ACGIH 1983)
IDLH: 200 ppm (NIOSH/OSHA 1978, p. 154)
Other Limits Recommended: Allowable tolerance for residues in
agricultural commodities: 0.01 ppm (*USEPA 1983). Maximum Air
Concentration (USSR) 0.1 mg/m3 (Encyc Occupat Health and Safety 1983,
p. 1681).
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 154)
Skin: No (*Rumack 1975 to Present)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Phosphine is a super- toxic
gas with a probable oral lethal dose of 5 mg/kg or 7 drops for a 150 pound
person (*Gosselin 1976). An air concentration of 3 ppm is safe for long
term exposure, 500 ppm is lethal in 30 minutes, and a concentration of
1,000 ppm is lethal after a few breaths (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Dangerous fire hazard from spontaneous chemical
reaction
LEL: 1.79% (*Spencer 1982)
UEL: Not Found
Extinguishing Methods: If material is on fire or involved in a fire, do
not extinguish unless flow can be stopped; use water in flooding quantities
as fog; cool all affected containers with flooding quantities of water;
apply water from as far a distance as possible; solid streams of water may
be ineffective; use "alcohol" foam, carbon dioxide or dry chemical (Student
1981, p. 405).
Special Fire Fighting Procedures: Wear full protective clothing including
self-contained breathing apparatus, rubber gloves, boots, and bands around
legs, arms, and waist. No skin surface should be exposed (*NFPA 1978).
For massive fires in cargo areas, use unmanned hose holders or monitor
nozzles. Move containers from fire area (DOT 1984, Guide 18).
Unusual Fire and Explosion Hazards: Phosphine can explode with powerful
oxidizers (Sax 1986, p. 138). The gas is heavier than air and may travel
along the ground to an ignition source (DASE 1980, p. 741).
Container may explode in heat of fire (DOT 1984, Guide 18).
NFPA Flammability Rating: 4
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CAS Registry Number: 7803-51-2
Page 3 of 4
PHOSPHINE
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, up to 55°C (*Spencer 1982)
Conditions to Avoid: May become unstable at high temperatures (*NFPA
1978). Reacts violently with air (Sax 1984, p. 2212).
Incompatibility (Materials to Avoid): Reacts violently with: air; boron
trichloride; bromine; chlorine; chlorine monoxide; nitric acid; nitric
oxide; nitrous oxide; nitrogen trioxide; silver nitrate; nitrous acid;
mercuric nitrate; nitrogen trichloride; oxygen; and (potassium plus
ammonia) (Sax 1984, p. 2212).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of phosphorus oxides (Sax 1984, p. 2212).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide used for fumigation of animal feed, leaf stored tobacco, and
box cars; also used for rodent control (*Spencer 1982). Doping agent for
solid state electronic components; polymerization initiator, condensation
catalyst (*SRI). Aluminum phosphine and magnesium phosphide are registered
as pesticides in the U.S.; they produce phosphine (USEPA/Pesticide Index
1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate area and deny entry. Stay upwind and
keep out of low areas. Ventilate closed spaces. Isolate hazard area for
one-half mile in all directions if tank car or truck is involved in fire.
Use water spray to reduce vapors; isolate area until gas has dispersed.
Shut off ignition sources; no flares, smoking or flames in hazard area.
Stop leak if you can do so without risk (DOT 1984, Guide 18).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 7803-51-2
Page 4 of 4
PHOSPHINE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Neoprene POOR/MANY
PE POOR/LIMITED
PVC POOR/LIMITED
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 7803-51-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
PHOSPHINE
(7803-51-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Colorless gas or liquid under pressure.
Odor - Fishy or garliclike.
Commercial Form - Gas.
Uses - Chemical intermediate, polymerization initiator, condensation catalyst,
doping agent, pesticide, fumigant.
Material to Avoid - Oxygen (except for use in emergency life support).
Caution: Highly flammable. May spontaneously ignite in air or explode when
mixed with oxygen. Avoid sources of extreme heat or ignition including sparks
or fire.
Other Names - Celphos, Delicia, Detia, hydrogen phosphide, phosphoretted
hydrogen, phosphorus trihydride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, diazepam, phenytoin.
Signs and Symptoms of Acute Phosphine Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
Acute exposure to phosphine usually results in headache, cough, tightness and
pain in the chest, shortness of breath, dizziness, lethargy, and stupor.
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EFATG
CAS Registry Number: 7803-51-2
Page 2 of 3
PHOSPHINE
Fatigue, muscle pain, chills, tremors, incoordination, seizures, and coma may
be seen. Pulmonary edema and cardiac arrhythmias are common.
Gastrointestinal symptoms include nausea, vomiting, abdominal pain, and
diarrhea. Renal (kidney) damage, hepatic (liver) damage, and jaundice may also
occur. Contact with phosphine may burn the skin and eyes.
Emergency Life-Support Procedures:
Acute exposure to phosphine may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosphine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosphine.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
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EFATG
CAS Registry Number: 7803-51-2
Page 3 of 3
PHOSPHINE
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
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CAS Registry Number: 8001-35-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CAMPHECHLOR
CAS Registry Number: 8001-35-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 786) Toxaphene; Agricide
Maggot Killer; Alltex; Alltox; Camphochlor; Camphoclor; Camphophene Huileux;
Chem-Phene; Chlorinated Camphene; Chlorocamphene; Chlor Chem T-590; Compound
3956; Crestoxo; Cristoxo; Cristoxo 90; ENT 9,735; Estonox; Fasco-terpene;
Geniphene; Gy-phene; Hercules 3956; Hercules Toxaphene; Kamfochlor; M 5055;
Melipax; Motox; NCI-C00259; Octachlorocamphene; PCC; Phenacide; Phenatox;
Polychlorcamphene; Polychlorinated Camphenes; Polychlorocamphene; Strobane-T;
Synthetic 3956; Toxadust; Toxakil; Toxon 63; Toxypen; Vertac 90%
Chemical Formula: C10H10C18 approximate (Hawley 1981, p. 1034)
Molecular Weight: Unknown
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (dog)
15 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): Yes
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.65 (*Worthing 1976)
Vapor Pressure (mmHg): 0.4 at 25°C (*Sunshine 1969)
Melting Point: 149-194°F, 65-90°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 3 mg/liter at room temperature (*Worthing 1979)
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CAS Registry Number: 8001-35-2
Page 2 of 4
CAMPHECHLOR
SECTION II (continued)
Appearance and Odor: Yellow, waxy solid with a pleasant piney odor
(*Merck 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.5 mg/ms (NIOSH 1987, p. 74)
ACGIH TLV: TWA 0.5 mg/m8; STEL 1 mg/m8 (skin) (ACGIH, 1986-87, p. 12)
IDLH: 200 mg/ms (NIOSH 1987, P.74)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 63)
Skin: Yes (NIOSH/OSHA 1978, p. 63)
Ingestion: Yes (NIOSH/OSHA 1978, p. 63)
Health Hazards (Acute, Delayed, and Chronic): Camphechlor is extremely
toxic: the probable oral lethal dose (human) is 5-50 mg/kg or between 7
drops and 1 teaspoonful for 70 kg (150 Ib.) person (*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 84°F, 29°C (CC) (Weiss 1980, p. 874)
Flammable Limits:
LEL: 1.1% (Weiss 1980, p. 874)
UEL: 6.4% (Weiss 1980, p. 874)
Extinguishing Methods: Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide
55). Water may be ineffective on fire (Weiss 1980, p. 874).
Special Fire Fighting Procedures: Move container from fire area if this
can be done without risk. Fight fire from a maximum distance. Dike fire
control water for later disposal; do not scatter the material. Wear
positive pressure breathing apparatus and special protective clothing (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: Container may explode in heat of fire
(DOT 1984, Guide 55). Toxic vapors are generated when heated (Weiss 1980,
p. 874).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Merck 1983)
Stable:
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CAS Registry Number: 8001-35-2
Page 3 of 4
CAMPHECHLOR
SECTION V (continued)
Conditions to Avoid: Dehydrochlorinates in the presence of alkali, on
prolonged exposure to sunlight, and at temperatures above 155C (*Merck
1983).
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1984,
p. 62); corrosive to iron (Merck 1983, p. 9384).
Hazardous Decomposition or Byproducts: Releases hydrochloric acid in the
presence of alkali, on prolonged exposure to sunlight, and at temperatures
above 155C (*Merck 1983).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Insecticide, primarily for cotton and early growth stages of vegetables
(Hawley 1981, p. 1034). Also peas, soybeans, peanut, corn, and wheat. Not
produced commercially in the U.S. since 1982 (*SRI). Only registered for
scabies control on cattle in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Wash away any material which may have contacted the body
with copious amounts of water or soap and water (Student 1981, p. 504;
DOT 1984, Guide 55). In case of land spill, dig a pit, pond, lagoon, or
holding area to contain the liquid or solid material. Cover solids with a
plastic sheet to prevent dissolving in rain or firefighting water. In case
of water spill, if camphechlor is dissolved, apply activated carbon at ten
times the spilled amount in region of 10 ppm or greater concentration.
Remove trapped material with suction hoses. Use mechanical dredges or
lifts to remove immobilized masses of pollutants and precipitates (Student
1981, p. 504).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 8001-35*2
Page 4 of 4
CAMPHECHLOR
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Acute toxicity is manifested as
generalized convulsions preceded by cyanosis. Also reported is sudden
exertional dyspnea (labored breathing), tachycardia (rapid heart rate),
weakness and low blood pressure (Gosselin 1984, p. III-387). Lethal doses
cause respiratory failure. Hypersalivation, leg and back muscle spasms,
nausea, vomiting, hyperexcitability, tremors, shivering, clonic
convulsions, and tetanic muscular contractions of all skeletal muscles have
also been reported (Weiss 1980, p. 874).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 8065-48-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DEMETON
CAS Registry Number: 8065-48-3
Synonyms: Phosphorothioic Acid, O,O-Diethyl O-(2-(Ethylthio)Ethyl) Ester
Mixed with O,O-Diethyl S-(2-(Ethylthio)Ethyl)Ester (7:3); Systox; O,O-Diethyl O
(and S)-2-(Ethylthio)Ethyl Phosphorothioate Mixture; Phosphorothioic acid,
O,O-diethyl O-(2-(ethylthio)ethyl) ester, mixed with O,O-diethyl
S-(2-(ethylthio)ethyl)phosphorothioate; Isosystox; Thioldemeton; BAY 10756;
Bayer 8169; Demeton-O and Demeton-S; Demox; Diethoxythiophosphoric Acid Ester
of 2-Ethylmercaptoethanol; E 1059; ENT 17,295; Ethyl Systox; Mercaptofos;
Mercaptophos; O,O-Diethyl-2-Ethylmercaptoethyl Thiophosphate; Septox; Systemox;
UVL; O,O-Diethyl-O-[2-(ethylmercapto)ethyl]Thionophosphate; Dematon;
beta-Ethylmercaptoethyl Diethyl Thionophosphate; Diethoxythiophosphoric Acid
Ester of 2-Ethylmercaptoethanol
Chemical Formula: C8H19O3PS2-C8H19OSPS2
Molecular Weight: 258.34
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
1.7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 273°F, 134°C at 2 mmHg (*Merck 1983)
Specific Gravity (H2O=1): 1.183 (*Clayton and Clayton 1981-82)
Vapor Pressure (mmHg): 0.00026 (""Hartley 1983)
Melting Point: -13°F, -25°C (NIOSH/OSHA 1978, p. 78)
Vapor Density (AIR=1): Heavier than air (*CHRIS 1978)
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CAS Registry Number: 8065-48-3
Page 2 of 4
DEMETON
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Demeton-O: 60 mg/L; Demeton-S: 2 g/L at room
temperature (*Worthing 1983)
Appearance and Odor: Oily liquid (*Merck 1976); amber color (*Osol 1980);
sulfur odor (*ACGIH 1980)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 mg/ms (skin) (*NIOSH/RTECS 1985)
ACGIH TLV: TWA 0.01 ppm, (0.1 mg/m3) (skin) (ACGIH 1986-87, p. 15)
IDLH: 20 mg/ms (*Encyc Occupat Health and Safety 1983)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Gosselin 1984)
Health Hazards (Acute, Delayed, and Chronic): This material is a
cholinesterase inhibitor (*Merck 1983). It is readily absorbed through the
skin (*Sax 1979) and is extremely toxic. Probable human lethal oral dose
is 5-50 mg/kg or 7 drops to 1 teaspoonful for 150 Ib. person (*Gosselin
1984). Acute dose is believed to be 12 to 20 mg by oral route (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 1139°F, 45°C (CC) (solution in combustible
solvent) (*CHRIS 1978)
Flammable Limits:
LEL: 1% (solution in combustible solvent) (*CHRIS 1978)
UEL: 5.3% (solution in combustible solvent) (*CHRIS 1978)
Extinguishing Methods: Use dry chemical, foam, carbon dioxide. Water may
be ineffective (*CHRIS 1978)
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Flammable Liquid, n.o.s.) Wear positive pressure breathing
apparatus and special protective clothing. Move containers from fire area.
Dike fire control water for later disposal; do not scatter the material.
Cool containers that are exposed to flames with water from the side until
well after fire is out. Withdraw immediately in case of rising sound from
venting safety device or any discoloration of tank due to fire. Isolate
for 1/2 mile in all directions if tank car or truck is involved in fire
(DOT 1984, Guide 28).
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CAS Registry Number: 8065-48-3
Page 3 of 4
DEMETON
SECTION IV (continued)
Unusual Fire and Explosion Hazards: May release sulfur oxides and
phosphoric acid. Solvent carrier vapors may travel on ground to ignition
source (*CHRIS 1978)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*CHRIS 1978)
Conditions to Avoid: Mixtures with water or polar solvents, in which
sulfur is lost to oxygen (*White-Stevens 1971); air and light, which
cause hydrolysis (*Sunshine 1969); alkaline mixtures and oxidizing
agents (*Hartley 1983).
Incompatibility (Materials to Avoid): Strong oxidizers (NIOSH/OSHA 1978,
P. 78)
Hazardous Decomposition or Byproducts: When heated, it emits sulfur
oxides and phosphoric acid (*CHRIS 1978).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used primarily as an agricultural insecticide (*Merck
1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Spills may be cleaned up by absorbing the material in vermiculite, dry
sand, earth, or a similar material (*NIOSH/OSHA 1981). General precautions
for organophosphorous pesticides are as follows. Keep unnecessary people
away; stay upwind. Shut off ignition sources; no flares, smoking, or
flames in hazard area. Do not touch spilled material. Use water spray
to reduce vapors. Take up spills with noncombustible absorbent material.
For large spills, dike far ahead (DOT 1984, Guide 28).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
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CAS Registry Number: 8065-48-3
Page 4 of 4
DEMETON
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 8065-48-3
Page 1 of 4
Emergency First Aid Treatment Guide
for
DEMETON
(8065-48-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Oily, amber-colored liquid.
Odor - Sulfurlike.
Commercial Form - 25 to 66% demeton in xylene solution.
Use - Pesticide.
Other Names - Bay 10756, E 1059, Ethyl Systox, Mercaptofos, Septox, Systemox.
Note: Demeton is a mixture of phosphorothioic acid, O,O-diethyl O-(2-
(ethylthio)ethyl)ester and O,O-diethyl S-(2-(ethylthio)ethyl) ester.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Demeton Exposure:
Warning: Demeton is readily absorbed through the skin. Effects may be delayed
up to 12 hours. Caution is advised.
Note: Demeton is a cholinesterase inhibitor.
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EFATG
CAS Registry Number: 8065-48-3
Page 2 of 4
DEMETON
Acute exposure to demeton may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
The heart rate may decrease following oral exposure or increase following
dermal exposure. Chest pain may be noted. Hypotension (low blood pressure)
may occur, although hypertension (high blood pressure) is not uncommon.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
Emergency Life-Support Procedures:
Acute exposure to demeton may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as demeton-resistant plastic sheeting and disposable
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to demeton.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to demeton.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
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EFATG
CAS Registry Number: 8065-48-3
Page 3 of 4
DEMETON
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of demeton is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of demeton may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4,
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
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EFATG
CAS Registry Number: 8065-48-3
Page 4 of 4
DEMETON
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 10025-73-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CHROMIC CHLORIDE
CAS Registry Number: 10025-73-7
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 922): Chromium(HI)
Chloride; Chromium Chloride; Chromium Chloride, Anhydrous; Chromium
Trichloride; CI 77295; Puratronic Chromium Chloride; Trichlorochromium
Chemical Formula: CrCl3
Molecular Weight: 158.35
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.0315 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 1/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Chromium Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Dissociates above 1300°C (Merck 1983, p. 316)
Specific Gravity (H2O=1): 2.87 (Merck 1983, p. 316)
Vapor Pressure (mmHg): Not Found
Melting Point: 2106°F, 1152°C (Merck 1983, p. 316)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Hawley 1981, p. 248); slightly soluble in
hot water (Weast 1984, p. B-85).
Appearance and Odor: Violet, lustrous, hexagonal, crystal scales; greasy
feel (Merck 1983, p. 316).
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CAS Registry Number: 10025-73-7
Page 2 of 3
CHROMIC CHLORIDE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Chromium Metal and Insoluble Salts) TWA 1.0 mg/m3
(NIOSH 1987, Appendix D)
ACGIH TLV: (Chromium (III) Compounds, as Chromium) TWA 0.5 mg/ms (ACGIH
1985, p. 14)
IDLH: Not Found
Other Limits Recommended: (Chromium metal and insoluble salts), IDLH
500 mg/m3, as chromium (NIOSH 1987, p. 82).
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 70)
Skin: Yes (Sax 1984, p. 791)
Ingestion: Yes (Sax 1984, p. 791)
Health Hazards (Acute, Delayed, and Chronic): It displays high dermal
toxicity, and moderate oral toxicity (Sax 1984, p. 791).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of chlorine containing compounds (Sax 1984, p. 791).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Strong oxidizers (NIOSH/OSHA 1978, p. 70)
Incompatibility (Materials to Avoid): Violent reaction with lithium,
nitrogen (Sax 1984, p. 791).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorine containing compounds (Sax 1984, p. 791).
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CAS Registry Number: 10025-73-7
Page 3 of 3
CHROMIC CHLORIDE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
In chromizing; in the manufacture of chromium metal and compounds; as a
catalyst for polymerization of olefins and other organic reactions; as a
textile mordant; in tanning; in corrosion inhibitors; and as a
waterproofing agent (Merck 1983, p. 316).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material. Avoid inhalation (see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 10025-73-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
CHROMIC CHLORIDE
(10025-73-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Violet, lustrous, hexagonal, crystalline scales.
Commercial Form - Dark green salt.
Uses - Metal tanning, chromium plating, textile mordant, corrosion inhibitor,
polymerization catalyst, waterproofing, manufacture of olefins.
Other Names - Chromium (III) chloride, chromium chloride, chromium trichloride,
puratronic chromium chloride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, milk, ascorbic acid, normal
saline, D5W, Ringer's lactate, magnesium hydroxide (or another antacid), sodium
bicarbonate, KC1, furosemide, mannitol, dopamine.
Signs and Symptoms of Acute Chromic Chloride Exposure:
Warnings: Effects may not appear for several days. Caution is advised.
Acute exposure to chromic chloride may produce signs and symptoms that include
corneal injury, oral burns, deep perforating ulcers, gastrointestinal
inflammation, and hemorrhage. Pulmonary edema, bronchial asthma, circulatory
collapse, and shock may also occur.
Delayed effects such as hepatic encephalopathy, pneumoconiosis, acute
hepatitis, renal failure, anemia, and thrombocytopenia may take as many as
7 days to manifest. Hospitalization is essential.
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CAS Registry Number: 10025-73-7
Page 2 of 3
CHROMIC CHLORIDE
Emergency Life-Support Procedures:
Acute exposure to chromic chloride may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to chromic chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to chromic chloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas with a 10 to 20% ascorbic acid solution for
15 minutes. If ascorbic acid solution is unavailable, water may be used.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
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EFATG
CAS Registry Number: 10025-73-7
Page 3 of 3
CHROMIC CHLORIDE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activated charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
6. RUSH to a health care facility.
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CAS Registry Number: 10025-87-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHORUS OXYCHLORIDE
CAS Registry Number: 10025-87-3
Synonyms: Phosphoric Chloride; Phosphoric Trichloride; Phosphoroxychloride;
Phosphorus Chloride; Phosphorus Chloride Oxide; Phosphorus Oxide Trichloride;
Phosphorus Oxytrichloride; Phosphoryl Chloride; Phosphoryl Trichloride;
Trichlorophosphine Oxide; Trichlorophosphorus Oxide
Chemical Formula: C13OP
Molecular Weight: 153.32
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.3 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1,000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 223°F, 106°C (*Merck 1976)
Specific Gravity (H2O=1): 1.645 at 25°C (*Merck 1976)
Vapor Pressure (mmHg): 40 at 27.3°C (*Sax 1979)
Melting Point: 34.2°F, 1.25°C (*Merck 1976)
Vapor Density (AIR=1): 5.3 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water (*Hawley 1977); reacts
exothermically with water (Merck 1983, p. 1060)
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CAS Registry Number: 10025-87-3
Page 2 of 4
PHOSPHORUS OXYCHLORIDE
SECTION II (continued)
Appearance and Odor: Colorless to light yellow, oily liquid with a
pungent, musty odor (*CHRIS 1978).
SECTION III ~ HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.1 ppm (0.6 mg/ms); STEL 0.5 ppm (3.0 mg/ms) (*ACGIH
1980)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (Sax 1984, p. 2225)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): This poison is toxic by
inhalation and ingestion and is strongly irritating to skin and tissues
(*Hawley 1977). It causes burns of the mucous membranes of the mouth and
digestive tract (*Lefaux 1968), and may be fatal (DASE 1980, p. 749).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Flammable
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish by smothering with suitable dry
chemical. Use water on combustibles burning in vicinity of this material
(*NFPA 1978). Use dry chemical, carbon dioxide, or dry sand; do not use
water on material itself; if large quantities of combustibles are involved,
use water in flooding quantities as spray and fog; use water spray to
absorb vapors; cool all affected containers with flooding quantities of
water; apply water from as far a distance as possible (Student 1981, p.
406).
Special Fire Fighting Procedures: Avoid breathing vapors; keep upwind.
Wear self-contained breathing apparatus. Avoid bodily contact with the
material. Wear boots, protective gloves, and goggles. Do not handle
broken packages without protective equipment. Wash away any material which
may have contacted the body with copious amounts of water or soap and
water. If contact with the material is anticipated, wear full protective
clothing (Student 1981, p. 406). Keep unnecessary people away; isolate
hazard area and deny entry (DOT 1984, Guide 39).
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CAS Registry Number: 10025-87-3
Page 3 of 4
PHOSPHORUS OXYCHLORIDE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: Poisonous, corrosive, and irritating
gases are generated when this material is heated or is in contact with
water (Weiss 1980, p. 747). It may ignite other combustible materials
(wood, paperi oil, etc.). It reacts violently with water (DOT 1984, Guide
39).
NFPA Flammability Rating: 0
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 747)
Conditions to Avoid: Do not store with combustible materials,
particularly fibrous organic materials, or with electrical or other
equipment that can be corroded. Reacts violently with moisture (*NFPA
1978).
Incompatibility (Materials to Avoid): Incompatible with carbon disulfide;
N,N-dimethylformamide; 2,5-dimethylpyrrole; 2,6-dimethyl- pyridine N-oxide;
dimethylsulf oxide; Ferrocene-1,1-dicarboxylic acid; water; and zinc (Sax
1984, p. 2225).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of chlorides and oxides of phosphorus; it will react with
water or steam to produce heat and toxic and corrosive fumes (Sax 1984, p.
2225).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used as a solvent in cryoscopy (*Merck 1976); chemical intermediate
for cresyldiphenyl phosphate, tricresyl phosphate, triphenylphosphate, and
other cyclic and acylic phosphate esters; organic chlorinating agent
(*SRI); manufacture of plasticizers, hydraulic fluids, gasoline additives,
and fire retarding agents; and as a catalyst (*ACGIH 1980).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep material out of water sources and sewers; build dikes to contain
flow as necessary; use water spray to knock down vapors; do not use water
on material itself; and neutralize spilled material with crushed
limestone, soda ash, or lime. For a land spill, dig a pit, pond, lagoon,
or holding area to contain liquid or solid material; dike surface flow
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CAS Registry Number: 10025-87-3
Page 4 of 4
PHOSPHORUS OXYCHLORIDE
SECTION VII (continued)
using soil, sand bags, foamed polyurethane, or foamed concrete; absorb
bulk liquid with fly ash or cement powder; neutralize with agricultural lime
(slaked lime), crushed limestone, or sodium bicarbonate. For a water spill,
neutralize with agricultural lime (slaked lime), crushed limestone,
or sodium bicarbonate; use mechanical dredges or lifts to remove
immobilized masses of pollutants and precipitates; adjust pH to neutral
(pH-7). For air spills apply water spray or mist to knock down vapors;
vapor knock down water is corrosive or toxic and should be diked for
containment (Student 1981, p. 406). Stop leak if you can do so without
risk. Do not touch spilled material. Keep combustibles (wood, paper,
oil, etc.) away from spilled material. Clean up only under supervision
of an expert (DOT 1984, Guide 39).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE POOR/LIMITED
Neoprene POOR/MANY
Nonwovwen PE POOR/MANY
PVC POOR/MANY
Saranex POOR/LIMITED
Viton POOR/LIMITED
*Based on qualitative performance information.
"""Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include burns and extensive
reddening of eyes, pains in throat, coughing, labored breathing with a
shortness of breath (*Lefaux 1968), dizziness, headache, weakness, nausea,
vomiting, chest pain, bronchitis, bronchopneumonia, pulmonary edema and
kidney damage (*ACGIH 1980).
Emergency and First Aid Procedures: Move victim to fresh air, call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. Speed in removing materials from skin is
of extreme importance. In case of contact with material, immediately flush
skin or eyes with running water for at least 15 minutes (DOT 1984, Guide
39).
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CAS Registry Number: 10026-13-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHORUS PENTACHLORIDE
CAS Registry Number: 10026-13-8
Synonyms: Pentachlorophosphorane; Pentachlorophosphorus; Phosphorane,
Pentachloro-; Phosphoric Chloride; Phosphoric Perchloride; Phosphorous
Pentachloride; Phosphorus Chloride; Phosphorus Pentachloride, Solid; Phosphorus
Perchloride; Phosphorus(V) Chloride
Chemical Formula: PC15
Molecular Weight: 208.27
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.205 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 320°F, 160°C (*Merck 1976)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 1 at 55.5°C (*Sax 1975)
Melting Point: (decomposes) 298°F (148°C) (under pressure) sublimes at
about 100°C without melting (*Merck 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Reacts violently with water (Sax 1984, p. 2223)
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CAS Registry Number: 10026-13-8
Page 2 of 4
PHOSPHORUS PENTACHLORIDE
SECTION II (continued)
Appearance and Odor: Pale yellow solid with an odor like hydrochloric
acid (NIOSH/OSHA 1978, p. 154); white to pale yellow crystalline with a
pungent, unpleasant odor (*Merck 1976).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 1 mg/m3 (NIOSH/OSHA 1978, p. 154)
ACGIH TLV: TWA 0.1 ppm (1.0 mg/m3) (ACGIH 1983, p. 29)
IDLH: 200 mg/m3 (NIOSH/OSHA 1978, p. 154)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2223)
Skin: Yes (Sax 1984, p. 2223)
Ingestion: Yes (Sax 1984, p. 2223)
Health Hazards (Acute, Delayed, and Chronic): It can cause death due to
pulmonary edema (Encyc Occupat Health and Safety 1983, p. 1683) or by
circulatory shock (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: If material is involved in fire then use dry
chemical, carbon dioxide, or dry sand. Do not use water on material
itself. If large quantities of combustibles are involved, use water in
flooding quantities (i.e., spray or fog), and use water spray to absorb
vapors (Student 1981, p. 407).
Special Fire Fighting Procedures: Avoid breathing vapors; keep upwind.
Wear self-contained breathing apparatus. Avoid bodily contact with the
material; wear boots, protective gloves, and goggles (Student 1981, p.
407).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits highly toxic fumes of chlorides and chlorine (see Section IV below).
Will react with water or steam to produce heat and toxic and corrosive
fumes. Reacts violently with moisture, chlorine trioxide, fluorine
hydroxylamine, magnesium oxides, diphosphorus trioxide, sodium and
potassium (Sax 1984, p. 2223). Decomposed by water to form hydrogen
chloride, phosphoric acids, corrosive materials, and heat. This heat may
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CAS Registry Number: 10026-13-8
Page 3 of 4
PHOSPHORUS PENTACHLORIDE
SECTION IV (continued)
be sufficient to ignite surrounding combustible materials (Student 1981, p.
407).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*Clayton and Clayton 1981-82)
Stable:
Conditions to Avoid: Produces phosphorus trichloride and chlorine
when heated (*Clayton and Clayton 1981-82).
Incompatibility (Materials to Avoid): Water, magnesium oxide, chemically
active metals: sodium, potassium; alkalis (NIOSH/OSHA 1978, p. 154).
Aluminum; chlorine dioxide; chlorine; diphosphorus trioxide; fluorine;
hydroxylamine; magnesium oxide; 3'-methyl-2-nitrobenzanilide; nitrobenzene;
sodium; urea; water (Sax 1984, p. 2223).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits highly toxic fumes of chlorides (Sax 1984, p. 2223). It is
decomposed by water to form hydrochloric and phosphoric acids, corrosive
materials and heat. This heat may ignite surrounding combustible material
(Student 1981, p. 407).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Chlorinating and dehydrating agent; (Hawley 1981, p. 811) catalyst in
manufacturing of acety'lcellulose and benzotrichloride from benzal chloride;
dehydrating agent (*SRI). Also used for converting acids into acid
chlorides (*Merck 1976).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep material out of water sources and sewers. Use water spray to knock
down vapors. Do not use water on material itself; neutralize spilled
material with crushed limestone, soda ash, or lime. Avoid breathing
vapors; keep upwind. Avoid bodily contact with the material;
Do not handle broken packages without protective equipment. Wash away any
materials which may have contacted the body with copious amounts of water
or soap and water (Student 1981, p. 407).
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CAS Registry Number: 10026-13-8
Page 4 of 4
PHOSPHORUS PENTACHLORIDE
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death by pulmonary edema or
circulation shock. Fumes cause irritation of eyes and respiratory
passages. Upon ingestion, immediate pain in the mouth and throat,
abdominal pain, nausea, vomiting of mucoid and "coffee-ground" material,
intense thirst, clammy skin, weak and rapid pulse, shallow respiration, and
circulatory shock occur (*Gosselin 1976; Encyc Occupat Health and Safety
1983, p. 1683).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Remove and isolate contaminated
clothing and shoes at the site. Speed in removing material from skin is of
extreme importance. In case of contact with material, immediately flush
skin or eyes with running water for at least 15 minutes. Keep victim quiet
and maintain normal body temperature (DOT 1984, Guide 39).
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CAS Registry Number: 10028-15-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - OZONE
CAS Registry Number: 10028-15-6
Synonyms: Oxygen, Mol; Triatomic Oxygen
Chemical Formula: O3
Molecular Weight: 48.00
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.0094 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -169.6°F, -111.9°C (*Weast 1979)
Specific Gravity (H2O=1): Gas: 2.144 g/liter at 0°C (*Weast 1979)
Vapor Pressure (mmHg): 41,257 (54 atm) at -12°C (DASE 1980, p. 710)
Melting Point: -314°F, -192.7°C (*Weast 1979)
Vapor Density (AIR=1): 1.7 (DASE 1980, p. 710)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 49 ml/100 ml at 0°C (*Weast 1979)
Appearance and Odor: Ozone is a colorless to bluish gas, a dark blue
liquid, or blue-black crystals (*Weast 1979; *Merck 1976). It has a
characteristic odor in concentrations less than 2 ppm (*Merck 1976).
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CAS Registry Number: 10028-15-6
Page 2 of 4
OZONE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 0.1 ppm (0.2 mg/ms) (OSHA 1984, p. 663)
ACGIH TLV: TWA 0.1 ppm (0.2 mg/ms); STEL 0.3 ppm (0.6 mg/ms) (*ACGIH
1982)
IDLH: 10 ppm (NIOSH/OSHA 1978, p. 176)
Other Limits Recommended: EEGL 1.0 ppm (60 minutes) (NRC 1984a, pp.
99-107).
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (*Sax 1979)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Ozone is highly toxic via
inhalation or by contact of liquid to skin, eyes, or mucous membranes. It
is capable of causing acute to chronic lung damage, burns, and death or
permanent injury (*Sax 1979). Ozone can be toxic at a concentration of 100
ppm for 1 minute (*NIOSH/RTECS 1985). Ozone is capable of causing death
from pulmonary edema (Doull 1980, p. 619). It increases sensitivity of the
lungs to bronchoconstrictors and allergens (*Gilman 1980); increases
susceptibility to and severity of lung bacterial and viral infections
(* ACGIH 1980).
Medical Conditions Generally Aggravated by Exposure: Ozone increased the
sensitivity of the lung to bronchoconstrictors (*Gilman 1980).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not .Found
Extinguishing Methods: In case of fire: keep cylinder cool by spraying
water (DASE 1980, p. 710).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Severe explosion hazard when shocked,
exposed to heat or flame, or by chemical reaction with organic substances,
especially reducing agents (*Rumack 1975 to Present). Ozone is a powerful
oxidizing agent (*Encyc Occupat Health and Safety 1971).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 10028-15-6
Page 3 of 4
OZONE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (*Encyc Occupat Health and Safety 1971).
Stable:
Conditions to Avoid: Contact with organic materials (Hawley 1981, p.
769)
Incompatibility (Materials to Avoid): Alkenes; aromatic compounds;
benzene, rubber; bromine; dicyanogen; diethyl ether; dinitrogen tetroxide;
hydrogen bromide; 4-hydroxy-4-methyl-l,6-heptadiene; nitrogen trichloride;
stibine; tetrafluorohydrazine (Sax 1984, p. 2110).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Disinfectant for air and water; used for bleaching waxes, textiles and oils
(*Merck 1976), ozonolysis of unsaturated fatty acids to pelargonic and
other acids; manufacture of ink; catalyst; water treatment for taste and
odor control; mold and bacteria inhibitor in cold storage; bleaching agent
(*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Irritating Agent, n.o.s.) Isolate area and deny entry.
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them (DOT 1984, Guide 58). Workers handling liquid ozone
should wear protective equipment designed for exposure to cryogenic liquid
(*Encyc Occupat Health and Safety 1971).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 10028-15-6
Page 4 of 4
OZONE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
'"Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 10028-15-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
OZONE
(10028-15-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to bluish gas.
Odor - Pungent.
Uses - Catalyst, bactericide, bleaching agent, industrial waste treatment,
purification of drinking water, deodorization of air and sewage gases,
production of peroxides, manufacture of ink.
Materials to Avoid - Oxidizable materials.
Other Names - O3, triatomic oxygen.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate.
Signs and Symptoms of Acute Ozone Exposure:
Warning: Effects may be delayed for 12 to 24 hours. Caution is advised.
Signs and symptoms of acute exposure to ozone may be severe and include
irritation and burns of the skin, eyes, and mucous membranes. An increased
respiratory rate, shallow breathing, cough, dyspnea (shortness of breath),
bronchitis, pulmonary edema, and pulmonary hemorrhage may occur. Tachycardia
(rapid heart rate) and hypotension (low blood pressure) may be observed.
-------
EFATG
CAS Registry Number: 10028-15-6
Page 2 of 3
OZONE
Neurologic effects include fatigue, dizziness, drowsiness, headache,
exhiliration, and depression. Nausea, vomiting, and anorexia may occur. Eye
exposure may result in conjuctivitis (red, inflamed eyes).
Emergency Life-Support Procedures:
Acute exposure to ozone may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to ozone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to ozone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. THOROUGHLY wash exposed skin areas with soap and water.
-------
EFATG
CAS Registry Number: 10028-15-6
Page 3 of 3
OZONE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
-------
CAS Registry Number: 10031-59-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- THALLIUM SULFATE
CAS Registry Number: 10031-59-1
Synonyms: (NIOSH/RTECS 1983 SYNONYMS, VOLUME 3, p. 706) Thallous Sulfate;
Ratox; Sulfuric Acid, Thallium Salt; Zelio
Chemical Formula: Tl(SO4)x
Molecular Weight:
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
16.0 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Thallium Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 632°C (Merck 1983, p. 9095)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
-------
CAS Registry Number: 10031-59-1
Page 2 of 4
THALLIUM SULFATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Thallium soluble compounds) TWA 0.1 mg (Tl)/m3 (skin) (NIOSH
1987, p. 224)
ACGIH TLV: (Thallium soluble compounds) TWA 0.1 mg (Tl)/ms (skin) (ACGIH
1986-87, p.31)
IDLH: Not Found
Other Limits Recommended: IDLH for thallium soluble compounds 20 mg/m3 (as
thallium) (NIOSH 1987, p. 224)
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 2557)
Health Hazards (Acute, Delayed, and Chronic): A dangerous, highly toxic
metal salt. Its main hazard is as a chronic poison due to its
accumulation, especially in liver, brain, and skeletal muscle. Fatal human
dose is about 500 mg of thallium. Many reported fatalities (Sax 1984, p.
2557).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Thallium Salts, n.o.s.) If
material is involved in fire, extinguish fire using agent suitable for type
of surrounding fire (material itself does not burn or burns with
difficulty). Use water in flooding quantities as fog. Use foam, carbon
dioxide or dry chemical (Student 1981, p. 497). For small fires use dry
chemical, carbon dioxide, water spray, or foam. For large fires use water
spray, fog, or foam. Move container from fire area if you can do so
without risk (DOT 1984, Guide 53).
Special Fire Fighting Procedures: (Non-Specific - Thallium Salts,
n.o.s.) For personnel protection avoid breathing dusts, and fumes from
burning material. Keep upwind. Avoid bodily contact with the material.
Wear boots, protective gloves, and goggles. Do not handle broken packages
without protective equipment. Wash away any material which may have
contacted the body with copious amounts of water or soap and water. Wear
self-contained breathing apparatus when fighting fires involving this
material. If contact with the material is anticipated, wear full
protective clothing (Student 1981, p. 497). Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
-------
CAS Registry Number: 10031-59-1
Page 3 of 4
THALLIUM SULFATE
SECTION IV (continued)
Wear self-contained (positive pressure if available) breathing apparatus
and full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of thallium and sulfur oxide (Sax 1984, p. 2557).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of thallium and sulfur oxides (Sax 1984, p. 2557).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Rodenticide (Sax 1984, p. 2557). Used for control of rats, moles and house
mice (Farm Chemicals Handbook 1984, p. C-223). Not registered as a
pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Thallium Salts, n.o.s.) Do not touch spilled material;
stop leak if you can do so without risk. Small spills: absorb with sand
or other noncombustible absorbent material and place into containers for
later disposal. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area. Large
spills: dike far ahead of spill for later disposal. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
-------
CAS Registry Number: 10031-59-1
Page 4 of 4
THALLIUM SULFATE
SECTION VIII (continued)
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: A dangerous, highly toxic metal salt.
Ingestion causes abdominal pain, vomiting, trembling, convulsions,
paralysis, shortness of breath, collapse, and death (Sax 1984, p. 2557).
Emergency and First Aid Procedures: (Non-Specific — Thallium Salts,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminated clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
COMMENTS
Sources searched but no information found:
Hawley 1981
Weast 1979
Merck 1983
NFPA 1984
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety 1983
Buchel 1983
Hayes 1982
-------
CAS Registry Number: 10102-18-8 .
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 9, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM SELENITE
CAS Registry Number: 10102-18-8
Synonyms: Selenious Acid, Disodium Salt; Disodium Selenite; Disodium Selenium
Trioxide; Sodium Selenium Oxide [Na2SeO3]; Selenious Acid
(H2SeO3), Disodium Salt
Chemical Formula: Na2O3Se
Molecularv Weight: 172.92
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): In Selenium Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Freely soluble in water (*Merck 1983). Soluble in
water to form a slightly alkaline solution/pentahydrate (*Clayton and
Clayton 1982).
-------
CAS Registry Number: 10102-18-8
Page 2 of 4
SODIUM SELENITE
SECTION II (continued)
Appearance and Odor: Tetragonal prisms (*Merck 1983). White crystals
(Sax 1984, p. 2451).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Selenium compounds) (TWA) 0.2 mg/ms, as selenium (NIOSH 1987,
p. 206)
ACGIH TLV: (Selenium compounds) (TWA) 0.2 mg/m8, as selenium (ACGIH 1986-
87, p. 29)
IDLH: Not Found
Other Limits Recommended: IDLH for selenium compounds 100 mg/ms (as
selenium) (NIOSH 1987, p. 206)
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2451)
Skin: Not Found
Ingestion: Yes (Hawley 1981, p. 951)
Health Hazards (Acute, Delayed, and Chronic): Toxic by ingestion (Hawley
1981, p. 951). In humans, a concentration of 5 ppm in food or 0.5 ppm in
milk or water has been estimated to be dangerous (selenium compounds)
(*Clarke 1981). Elemental selenium has low acute systemic toxicity, but
dust or fumes can cause serious irritation of the respiratory tract
(non-specific selenium compounds) (Sax 1984, p. 2390).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: dry chemical carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (*DOT 1984).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: May burn but will not ignite readily
(*DOT 1984). When heated to decomposition, may emit toxic fumes of
selenium and sodium oxide (Sax 1984, p. 2541).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 10102-18-8
Page 3 of 4
SODIUM SELENITE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes. Stable in air (*Merck 1983).
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition it
emits toxic fumes of selenium and sodium oxide (Sax 1984, p. 24S1).
Hazardous Polymerization: May Occur: Not Found
May Not Occur:
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Removing green color from glass during its manufacture; alkaloidal reagent
(*Merck 1983); reagent in bacteriology; testing germination of seeds;
decorating porcelain (*Hawley 1981). Livestock feed additive (*Peer Review
Committee).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing dust (see Section III above). Small spills: absorb with
sand or other non-combustible absorbent material and place into
containers for later disposal. Small dry spills: shovel material into
clean, dry container and cover. Large spills: dike far ahead of
spill for later disposal (*DOT 1984).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
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CAS Registry Number: 10102-18-8
Page 4 of 4
SODIUM SELENITE
SECTION VIII (continued)
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Selenium Compounds)
Garlic odor of breath is a common symptom. Pallor, nervousness,
depression, and digestive disturbances have been reported in cases of
chronic exposure (Sax 1984, p. 2390).
Emergency and First Aid Procedures: Isolate hazard area and deny entry.
Stay upwind; keep out of low areas. Wear self-contained (positive pressure
if available) breathing apparatus and full protective clothing. Move
victim to fresh air; call emergency medical care. Remove and isolate
contaminated clothing and shoes at the site. In case of contact with
material, immediately flush skin or eyes with running water for at least 15
minutes (*DOT 1984).
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CAS Registry Number: 10102-20-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SODIUM TELLURITE
CAS Registry Number: 10102-20-2
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 686): Telluric Acid,
Disodium Salt; Sodium Tellurate (IV); Tellurous Acid, Disodium Salt
Chemical Formula: Na2TeO3
Molecular Weight: 221.58
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in water (Merck 1983, p. 1242)
Appearance and Odor: White crystals (Weast 1979, p. B-129)
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CAS Registry Number: 10102-20-2
Page 2 of 4
SODIUM TELLURITE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Tellurium and compounds) TWA 0.1 mg/m3, as tellurium (NIOSH
1987, p. 216)
ACGIH TLV: (Tellurium and compounds) TWA 0.1 mg/ms, as tellurium (ACGIH
1986-87, p. 30)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Tellurium,
Compounds) (NIOSH/OSHA 1978, p. 173)
Skin: Yes (Sax 1984, p. 2454)
Ingestion: Yes (Sax 1984, p. 2454)
Health Hazards (Acute, Delayed, and Chronic): The material is both an
oral and dermal toxic hazard (Sax 1984, p. 2454). The material is toxic by
ingestion (Hawley 1981, p. 953). (Non-Specific -- Tellurium Compounds)
Oral ingestion of tellurium compounds is generally regarded as extremely
toxic. The probable oral lethal dose is 5-50 mg/kg or between 7 drops and
1 teaspoonful for a 70 kg (150 pound) person. Tellurium compounds are
regarded as super toxic for skin exposures (Gosselin 1976, p. 90).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 10102-20-2
Page 3 of 4
SODIUM TELLURITE
SECTION V (continued)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of tellurium and sodium monoxide (Sax 1984, p. 2454).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Sodium tellurite is used in bacteriology and medicine (Hawley 1981, p.
953).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Tellurium) Symptoms
include garlic odor of the breath and a metallic taste in the mouth,
drowsiness, and a loss of appetite (Encyc Occupat Health and Safety 1983,
p. 2156).
Emergency and First Aid Procedures: (Non-Specific — Tellurium Compounds)
Eyes: irrigate immediately. Skin: wash with soap and water immediately.
If breathed in large amounts, move to fresh air, perform artificial
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CAS Registry Number: 10102-20-2
Page 4 of 4
SODIUM TELLURITE
SECTION IX (continued)
respiration if necessary; keep person warm and at rest. If swallowed and
person is conscious, give large amounts of water and try to get the person
to vomit by having him touch the back of his throat with his finger
(NIOSH/OSHA 1978, p. 173).
COMMENTS
Sources searched but no information found:
DOT 1984
Student 1981
Weiss 1980
DASE 1980
NFPA 1984
CHRIS 1978
-------
CAS Registry Number: 10102-43-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NITRIC OXIDE
CAS Registry Number: 10102-43-9
Synonyms: Mononitrogen Monoxide; Nitrogen Monoxide; Nitrogen Oxide
Chemical Formula: NO
Molecular Weight: 30.01
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rabbit) 0.39 mg/liter/15 minutes
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -241.1°F, -151.7°C (*Merck 1976)
Specific Gravity (H2O=1): 1.27 at -150.2°C (*Merck 1976)
Vapor Pressure (mmHg): 26,000 at 20°C (*ACGIH 1980)
Melting Point: -262.5°F, -163.6°C (*Merck 1976)
Vapor Density (AIR=1): 1.04 (*Merck 1976)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 7.34 mL/100 mL at 0°C (*Weast 1979)
Appearance and Odor: Colorless gas; deep blue when liquid; bluish-white
snow when solid (*Merck 1976). Colorless gas with sharp, sweet odor; brown
at high concentrations in air (NIOSH/OSHA 1978, pp. 138-139).
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CAS Registry Number: 10102-43-9
Page 2 of 4
NITRIC OXIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: TWA 25 ppm (30 mg/ms) (NIOSH 1987, p. 174)
ACGIH TLV: TWA 25 ppm, 30 mg/m3; (ACGIH 1986-87, p. 25)
IDLH: 100 ppm (NIOSH/OSHA 1978, pp. 138-139)
Other Limits Recommended: NIOSH: 25 ppm (30 mg/ms) 10-hour TWA (NIOSH
1987, p. 174)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (NIOSH/OSHA 1978, p. 138)
Ingestion: Yes (NIOSH/OSHA 1978, p. 138)
Health Hazards (Acute, Delayed, and Chronic): Can cause death or
permanent injury after a very short exposure to small quantities (*Sax
1975). Irritant of eyes, nose, throat; can cause unconsciousness
(NIOSH/OSHA 1978, pp. 138-139). Nitric oxide forms acids in the
respiratory system which are irritating and cause congestion in the lungs.
Concentrations of 60-150 ppm cause immediate irritation of the nose and
throat with coughing and burning in the throat and chest. 6-24 hours after
exposure, labored breathing and unconsciousness may result. Concentrations
of 100-150 ppm are dangerous for short exposure of 30-60 minutes.
Concentrations of 200-700 ppm may be fatal after very short exposure (Sax
1984, p. 2004).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical or carbon
dioxide. For large fires, use water spray, fog, or foam (DOT 1984, Guide
20).
Special Fire Fighting Procedures: Wear positive pressure breathing
apparatus and full protective clothing. Move container from fire area if
you can do so without risk. Stay away from ends of tanks. Spray cooling
water on containers that are exposed to flames until well after fire is
out. For massive fire in cargo area, use unmanned hose holder or monitor
nozzles; if this is impossible, withdraw from area and let fire burn (DOT
1984, Guide 20).
Unusual Fire and Explosion Hazards: Burns only when heated with hydrogen
(*Merck 1976). With carbon disulfide, it reacts explosively with emission
of light. When mixed with chlorine monoxide, can be explosive. Explodes
on contact with nitrogen trichloride. When mixed with ozone, it will
-------
CAS Registry Number: 10102-43-9
Page 3 of 4
NITRIC OXIDE
SECTION IV (continued)
explode (*NFPA 1978). Will react with water or steam to produce heat and
corrosive fumes. Reacts vigorously with reducing materials. When heated
to decomposition, highly toxic fumes of nitrogen oxides are emitted (*Sax
1975). May ignite other combustible materials (wood, paper, oil, etc.).
Mixture with fuels may explode. Container may explode in heat of fire.
Vapor explosion and poison hazard indoors, outdoors or in sewers (DOT 1984,
Guide 20).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Sax 1975)
Conditions to Avoid: Storage in direct sunlight, or areas of high
fire hazard (*Sax 1975).
Incompatibility (Materials to Avoid): Aluminum, boron, carbon disulfide,
hypochlorite, chromium, fluorine, fuels, hydrocarbons, nitrogen
trichloride, ozone, phosphorus, uns-dimethyl hydrazine, uranium, acetic
anhydride, ammonia, barium oxide, boron trichloride, methyl chloride,
1,2-dichloroethane, dichloroethylene, ethylene, iron, magnesium, manganese,
olefins, potassium, propylene, sodium, sulfur, trichloroethylene, 1,1,1-
trichloroethane, uns-tetrachloroethane (Sax 1984, p. 2004); and reducing
agents (*Sax 1975).
Hazardous Decomposition or Byproducts: When heated to decomposition,
highly toxic fumes of nitrogen oxides are emitted. Reacts with water or
steam to produce heat and corrosive fumes (*Sax 1975). Reacts with oxygen
to form poisonous nitrogen dioxide (Student 1981, p. 368).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Manufacturing of nitric acid, in bleaching of rayon, stabilizer for
propylene, methyl ether (*Merck 1976), to prepare nitrosyl carbonyls
(*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Keep combustibles (wood, paper, oil, etc.) away from spilled
-------
CAS Registry Number: 10102-43-9
Page 4 of 4
NITRIC OXIDE
SECTION VII (continued)
material. Stop leak if you can do so without risk. Isolate area until gas
has dispersed (DOT 1984, Guide 20).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED*
CPE GOOD/LIMITED*
PVC GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death due to blockage of gas
exchange in lungs. Initially, symptoms include slight coughing, fatigue
and nausea at high concentrations, coughing, choking, headache, nausea,
abdominal pain and shortness of breath are seen. Latent symptoms are
uneasiness, restlessness, rapid and shallow breathing, bluing of skin, lips
and fingernail beds, anxiety, mental confusion, and finally loss of
consciousness (*Gosselin 1976).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult give oxygen. Remove and isolate contaminated
clothing and shoes at the site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Effects may be
delayed; keep victim under observation (DOT 1984, Guide 20).
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CAS Registry Number: 10102-44-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - NITROGEN DIOXIDE
CAS Registry Number: 10102-44-0
Synonyms: Nitrito; Nitro; Nitrogen Dioxide (liquid); Nitrogen Oxide (NO2);
Nitrogen Peroxide
Chemical Formula: NO2
Molecular Weight: 46.01
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(guinea pig) 0.056 mg/liter/hour (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 10 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: 70.07°F, 21.15°C (*Merck 1976)
Specific Gravity (H2O=1): 1.448 at 20°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): 720 at 20°C (*NIOSH/OSHA 1978, p. 140)
Melting Point: 15.3°F, -9.3°C (*Merck 1976)
Vapor Density (AIR=1): 1.58 (*Merck 1976)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble; decomposes (Weast 1980, p. B-103)
Appearance and Odor: Colorless solid, yellow liquid (*Weast 1979).
Reddish-brown gas, liquid below 21.15°C, has an irritating odor (*Merck
1976).
-------
CAS Registry Number: 10102-44-0
Page 2 of 4
NITROGEN DIOXIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Ceiling 5 ppm (9 mg/m3) (OSHA 1984, p. 663)
ACGIH TLV: TWA 3 ppm (6 mg/ms); STEL 5 ppm (10 mg/m3) (*ACGIH 1982)
IDLH: 50 ppm (NIOSH/OSHA 1978, p. 140)
Other Limits Recommended: NIOSH: 1.0 ppm (1.8 mg/m3) 15-minute ceiling
(NIOSH 1987, p. 176). SPEGL 1.0 ppm (60 minutes) (NRC 1985a, pp. 83-96).
Routes of Entry: Inhalation: Yes (*Sax 1979)
Skin: Yes (Student 1981, p. 371)
Ingestion: Yes (NIOSH/OSHA 1978, p. 141)
Health Hazards (Acute, Delayed, and Chronic): Severe exposures may be
fatal (DASE 1980, p. 685). Contact may cause burns to skin and eyes.
Contact with liquid may cause frostbite (DOT 1984, Guide 20). This
compound was reported to react with blood to form methemoglobin (*Gosselin
1978). The lowest lethal human inhalation dose has been reported at 200
ppm/1 min (*NIOSH/RTECS 1985).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Does not burn (*Merck 1983)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray, fog, or foam. For massive fire in cargo area, use unmanned
hose holder or monitor nozzles; if this is impossible, withdraw from area
and let fire burn (DOT 1984, Guide 20).
Special Fire Fighting Procedures: Move container from fire area if you
can do so without risk. Stay away from ends of tanks. Spray cooling water
on containers that are exposed to flames until well after fire is out (DOT
1984, Guide 20).
Unusual Fire and Explosion Hazards: When heated to decomposition, toxic
fumes of nitrogen oxides are emitted (Sax 1984, p. 2023). May ignite other
combustible materials (wood, paper, oil, etc.). Mixture with fuels may
explode. Container may explode in heat of fire. Vapor explosion and
poison hazard may occur indoors, outdoors or in sewers (DOT 1984, Guide
20).
NFPA Flammability Rating: 0
-------
CAS Registry Number: 10102-44-0
Page 3 of 4
NITROGEN DIOXIDE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 664)
Conditions to Avoid: Moisture and physical damage to storage
container (*NFPA 1978)
Incompatibility (Materials to Avoid): Incompatible with combustible
matter, chlorinated hydrocarbons, ammonia, carbon disulfide (NIOSH/OSHA
1978, p. 171). Reacts with alkalies to form nitrates and nitrites (*Merck
1976). Violent reaction with cyclohexane, fluorine, formaldehyde,
alcohols, nitrobenzene, petroleum, and toluene (Sax 1984, p. 2023).
Hazardous Decomposition or Byproducts: Decomposes in water forming nitric
acid and nitric oxide (*Merck 1976)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is used in bleaching flour; in initiation of organic compounds and
explosives; in manufacture of oxidized cellulose for acrylates (*Hawley
1977); as a chemical intermediate (captive) for nitric acid; and as a
catalyst for sulfuric acid (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Evacuate area endangered by gas (DOT 1984, Guide 20).
For water spills, neutralize with agricultural lime (slaked lime),
crushed limestone, or sodium bicarbonate. For an air spill, apply
water spray or mist to knock down vapors. Vapor knockdown water is
corrosive or toxic and should be diked for containment (Student 1981, p.
371). Keep combustibles (wood, paper, oil, etc.) away from spilled
material. Stop leak if you can do so without risk. Use water spray to
reduce vapor but do not put water on leak or spill area. Isolate area
until gas has dispersed (DOT 1984, Guide 20).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
-------
CAS Registry Number: 10102-44-0
Page 4 of 4
NITROGEN DIOXIDE
SECTION VIII (continued)
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED*
Viton/Neoprene POOR/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG »
CAS Registry Number: 10102-44-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
NITROGEN DIOXIDE
(10102-44-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Reddish-brown gas (high pressure or low temperature results in the
reversible formation of a yellow or brown liquid or colorless solid of nitrogen
tetroxide, CAS No. 10544-72-6).
Odor - Pungent, acrid, mildly irritating.
Commercial Form - 99.5% pure liquid in 125-, 150-, 2000-lb cylinders; tank
cars.
Uses - Bleaching flour, manufacture of oxidized cellulose, nitric acid,
catalyst for manufacture of sulfuric acid, component of explosives, oxidizer
for rocket fuels.
Materials to Avoid - Combustible matter, chlorinated hydrocarbons, ammonia,
alkali, formaldehyde, alcohol, petroleum, water (except for use in emergency
life support).
Caution: Nitrogen dioxide reacts violently with many substances, especially
reducing agents such as ammonia or amines. Spontaneous ignition is likely upon
contact with combustible matter. Nitrogen dioxide will decompose in water to
nitric acid and nitric oxide.
Other Names - Nitro, nitrogen peroxide.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
-------
* EFATG
CAS Registry Number: 10102-44-0
Page 2 of 3
NITROGEN DIOXIDE
Signs and Symptoms of Acute Nitrogen Dioxide Exposure:
Warning: Effects may be delayed for hours to days. Caution is advised,
Acute exposure to nitrogen dioxide may be severe and result in a weak, rapid
pulse; cyanosis (blue tint to the skin and mucous membranes); and circulatory
collapse. Cough, dyspnea (shortness of breath), bronchitis, pneumonitis, and
pulmonary edema may occur following inhalation exposure. Gastrointestinal
symptoms include nausea and abdominal pain. Fatigue, lethargy, restlessness,
fever, anxiety, headache, mental confusion, and loss of consciousness may also
occur. Contact with the skin and mucous membranes may result in severe
irritation and burns. When liquid nitrogen dioxide contacts the skin,
frostbite will result.
Emergency Life-Support Procedures:
Acute exposure to nitrogen dioxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to nitrogen dioxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to nitrogen dioxide.
-------
EFATG
CAS Registry Number: 10102-44-0
Page 3 of 3
NITROGEN DIOXIDE
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas with soap and water for at least 15 minutes.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Activa'ted charcoal is of no value.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
6. Transport to a health care facility.
-------
CAS Registry Number: 10124-50-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - POTASSIUM ARSENITE
CAS Registry Number: 10124-50-2
Synonyms: Arsenious Acid, Potassium Salt; Arsenenous Acid, Potassium Salt;
Arsonic Acid, Potassium Salt; Fowler's Solution; NSC 3060; Potassium Arsenite,
Solid; Potassium Metaarsenite
Chemical Formula: KAsO2HAsO2 (Weiss 1986, p. 848)
Molecular Weight: 253.9
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
14 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1,000 (pounds) (statutory)
Section 313 Listed (Yes or No): In Arsenic Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in water (*Weast 1979)
Appearance and Odor: White hygroscopic powder (*Merck 1976)
-------
CAS Registry Number: 10124-50-2
Page 2 of 4
POTASSIUM ARSENITE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/ms, as arsenic (NIOSH 1987,
P. 54)
ACGIH TLV: (Arsenic and compounds) 0.2 mg/ms, as arsenic (ACGIH 1986-87,
P. 10)
IDLH: Not Found
Other Limits Recommended: NIOSH: 0.002mg/m3 15-minute ceiling, as arsenic
(NIOSH 1987, p. 54)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Not Found
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): Very toxic: probable oral
lethal dose in humans is 50-500 mg/kg, or between 1 teaspoonful and one
ounce for a 150-lb. adult (*Gosselin 1976). It is a skin irritant and
allergen (*Sax 1975).
Medical Conditions Generally Aggravated by Exposure: Acute allergic
reactions to arsenic compounds are fairly common (Sax 1984, p. 2268-2269).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with dry chemical, carbon dioxide,
water spray or foam (*DOT 1984).
Special Fire Fighting Procedures: Keep unnecessary people away; stay
upwind; keep out of low areas. Wear full protective clothing and
self-contained breathing apparatus (DOT 1984, Guide 54).
Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gases (*DOT 1984)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (*IARC 1972-1985)
Stable:
Conditions to Avoid: Aeration (*IARC 1972-1985)
-------
CAS Registry Number: 10124-50-2
Page 3 of 4
POTASSIUM ARSENITE
SECTION V (continued)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Reduces silver salt to metallic silver during mirror silvering. Currently,
it is probably not being used (Merck 1983, p. 1098).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact. With clean shovel place material
into clean, dry container and cover; move containers from spill area.
Dike far ahead of spill for later disposal. Do not touch spilled
material; stop leak if you can do it without risk (DOT 1984, Guide 54).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Nausea, vomiting and diarrhea result from
arsenic ingestion. Patient may go into collapse and shock with weak, rapid
pulse, cold sweat, coma, and death. Chronic arsenic poisoning may manifest
itself by loss of appetite, cramps, nausea, constipation, or diarrhea.
-------
CAS Registry Number: 10124-50-2
Page 4 of 4
POTASSIUM ARSENITE
SECTION IX (continued)
Liver damage may cause jaundice. Itching or skin pigmentation changes may
occur (*Sax 1975).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. Remove and isolate contaminated clothing and shoes
at the site. In case of contact with material, immediately flush eyes with
running water for at least 15 minutes. Wash skin with soap and water (DOT
1984, Guide 54).
-------
CAS Registry Number: 10140-87-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ETHANOL, 1,2-DICHLORO-, ACETATE
CAS Registry Number: 10140-87-1
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 249): 1,2-Dichloroethyl
Acetate
Chemical Formula: C4H6C12O2
Molecular Weight: 157.00
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(rat) 0.10 mg/liter/4 hours (NIOSH/RTECS 1983, Volume 2, p. 249)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 136-149°F, 58-65°C at 13 mmHg (Hawley 1981, p. 335)
Specific Gravity (H2O=1): 1.296 at 20°C (Hawley 1981, p. 335)
Vapor Pressure (mmHg): Not Found
Melting Point: Less than -26°F, less than -32°C (Hawley 1981, p. 335)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Hawley 1981, p. 335)
Appearance and Odor: Water-white liquid (Hawley 1981, p. 335)
-------
CAS Registry Number: 10140-87-1
Page 2 of 4
ETHANOL, 1,2-DICHLORO-, ACETATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 335)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): This material is toxic by
inhalation (Hawley 1981, p. 335).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 307°F, 152°C (Hawley 1981, p. 335)
Flammable Limits: Combustible (Hawley 1981, p. 335)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Combustible Liquid, n.o.s.)
Small fires: dry chemical, carbon dioxide, water spray or foam. Large
fires: water spray, fog or foam (DOT 1984, Guide 27).
Special Fire Fighting Procedures: (Non-Specific -- Combustible Liquid,
n.o.s.) Move container from fire area if you can do it without risk. Cool
containers that are exposed to flames with water from the side until well
after fire is out. For massive fire in cargo area, use unmanned hose
holder or monitor nozzles; if this is impossible, withdraw from area and
let fire burn. Withdraw immediately in case of rising sound from venting
safety device or any discoloration of tank due to fire. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing. Isolate one-half mile in all directions if tank
car or truck is involved in fire (DOT 1984, Guide 27).
Unusual Fire and Explosion Hazards: (Non-Specific — Combustible Liquid,
n.o.s.) May be ignited by heat, sparks or flames. Vapors may travel to a
source of ignition and flash back. Container may explode in heat of fire.
Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may
create fire or explosion hazard (DOT 1984, Guide 27).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 10140-87-1
Page 3 of 4
ETHANOL, 1,2-DICHLORO-, ACETATE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): (Non-Specific - Esters) Esters
may explode on mixing with nitrates (Sax 1984, p. 1298).
Hazardous Decomposition or Byproducts: (Non-Specific — Chlorinated
Hydrocarbons, Aliphatic) When heated to decomposition, it may emit highly
toxic fumes of phosgene (Sax 1984, p. 673).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used in organic synthesis (Hawley 1981, p. 335).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Combustible Liquid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Shut off ignition sources; no flares, smoking or flames in hazard area.
Stop leak if you can do it without risk. Use water spray to reduce vapors.
Small spills: take up with sand or other non-combustible absorbent material
and place into containers for later disposal. Large spills: dike far
ahead of spill for later disposal (DOT 1984, Guide 27).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Combustible Liquid,
n.o.s.) Move victim to fresh air; call emergency medical care. If not
-------
CAS Registry Number: 10140-87-1
. Page 4 of 4
ETHANOL, 1,2-DICHLORO-, ACETATE
SECTION IX (continued)
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact with material, immediately flush eyes with
running water for at least 15 minutes. Wash skin with soap and water.
Remove and isolate contaminated clothing and shoes at the site (DOT 1984,
Guide 27).
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CAS Registry Number: 10210-68-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - COBALT CARBONYL
CAS Registry Number: 10210-68-1
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 950): Cobalt,
Di-mu-Carbonylhexacarbonyldi-, (Co-Co); Cobalt Octacarbonyl; Cobalt
Tetracarbonyl; Cobalt Tetracarbonyl Dimer; Di-mu-Carbonylhexacarbonyldicobalt;
Dicobalt Carbonyl; Dicobalt Octacarbonyl; Octacarbonyldicobalt
Chemical Formula: C8Co2O8
Molecular Weight: 341.94
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.027 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Cobalt Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes at 126°F, 52°C (Weast 1979, p. B-72)
Specific Gravity (H2O=1): 1.73 at 18°C (Weast 1979, p. B-72)
Vapor Pressure (mmHg): 0.07 at 15°C (Encyc Occupat Health and Safety
1983, p. 493)
Melting Point: 124°F, 51°C (Weast 1979, p. B-72)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. B-72)
Appearance and Odor: Orange or dark brown crystalline solid (Weast 1979,
p. B-72).
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CAS Registry Number: 10210-68-1
Page 2 of 4
COBALT CARBONYL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Cobalt metal, fume and dust) TWA 0.1 mg/m3, as cobalt (NIOSH
1987, p. 84)
ACGIH TLV: TWA 0.1 mg/m3, as cobalt (ACGIH 1986-87, p. 14)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 263)
Skin: Yes (Encyc Occupat Health and Safety 1983,
p. 493)
Ingestion: Yes (Hawley 1981, p. 263)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic. It is irritating to skin and mucous membranes (Merck 1983, p. 448).
Cobalt carbonyls share the general toxicity of carbonyls because of the
direct irritant and systemic action of the compound coupled with the
effects of carbon monoxide which is released from their decomposition
(Encyc Occupat Health and Safety 1983, p. 493).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits carbon monoxide (Sax 1984, p. 800)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (Merck 1983, p. 448)
Stable:
Conditions to Avoid: Decomposes on exposure to air (Merck 1983, p.
448)
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CAS Registry Number: 10210-68-1
Page 3 of 4
COBALT CARBONYL
SECTION V (continued)
Incompatibility (Materials to Avoid): Slowly attacked by hydrochloric
acid and sulfuric acid, more rapidly by nitric acid and bromine (Merck
1983, p. 448).
Hazardous Decomposition or Byproducts: Emits carbon monoxide when heated
to decomposition (Sax 1984, p. 800).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a catalyst for a number of reactions (Merck 1983,
p. 448). It is also used in anti-knock gasoline and for high-purity cobalt
salts (Hawley 1981, p. 263).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: The carbonyls are direct irritants (Sax
1984, p. 646). Carbon monoxide causes breathlessness, headache, weakness
and fatigue, nausea and vomiting, dimness of vision, collapse and coma
(Gosselin 1984, p. 111-98).
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. In case of
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Remove and isolate clothing and shoes at the site
(DOT 1984, Guide 53).
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CAS Registry Number: 10210-68-1
Page 4 of 4
COBALT CARBONYL
COMMENTS:
Sources searched but no information found:
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1986
Clayton and Clayton 1981-1982
Arena 1979
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
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CAS Registry Number: 10265-92-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHAMIDOPHOS
CAS Registry Number: 10265-92-6
Synonyms: Phosphoramidothioic Acid, O,S-Dimethyl Ester; Monitor;
Acephate-Met; BAY 71628; Bayer 5546; Bayer 71628; Chevron 9006; Chevron Ortho
9006; ENT 27,396; Hamidop; Metamidophos; Monitor (Insecticide); O,S-Dimethyl
Ester Amide of Amidothioate; O,S-Dimethyl Phosphoramidothioate; O,S-Dimethyl
Phosphoramidothiolate; Ortho 9006; RE 9006; SRA 5172; Tamaron
Chemical Formula: C2H8NO2PS
Molecular Weight: 141.14
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes (Worthing 1983, p. 359)
Specific Gravity (H2O=1): 1.31 at 44.5°C (*Worthing 1979)
Vapor Pressure (mmHg): 0.0003 at 30°C (*Worthing 1979)
Melting Point: 112°F, 44.5°C (*Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 90 g/liter at 20°C (*Farm Chemicals Handbook 1981);
greater than 2000 g/liter at 20°C (Worthing 1983, p. 359)
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CAS Registry Number: 10265-92-6
Page 2 of 4
METHAMIDOPHOS
SECTION II (continued)
Appearance and Odor: Crystalline solid (*Farm Chemicals Handbook 1981);
technical product is off-white (*Worthing 1979); pungent odor (*Spencer
1973).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Farm Chemicals Handbook 1981)
Skin: Yes (*Farm Chemicals Handbook 1981)
Ingestion: Yes (*Farm Chemicals Handbook 1981)
Health Hazards (Acute, Delayed, and Chronic): This material is harmful or
fatal if swallowed, inhaled, or absorbed through the skin (*Farm Chemicals
Handbook 1981).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 10265-92-6
Page 3 of 4
METHAMIDOPHOS
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes, at neutral pH (*Worthing 1979)
Conditions to Avoid: Strong acid or alkali (*Worthing 1979)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: (Non-Specific —
Phosphoramidothioic Acid, O-Ethyl S-Methyl Ester) Emits very toxic fumes
of nitrogen oxides, phosphorus oxides, and sulfur oxides when heated to
decomposition (Sax 1984, p. 2213).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as an insecticide on a number of vegetables and on
cotton (*SRI).
SECTION VII « PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do so without risk. Use water spray
to reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 10265-92-6
Page 4 of 4
METHAMIDOPHOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 10265-92-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHAMIDOPHOS
(10265-92-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Crystalline solid.
Odor - Pungent.
Commercial Form - Off-white, water-soluble concentrate.
Use - Pesticide.
Materials to Avoid - Alkali.
Other Names - Bayer 71628, Hamidop, Monitor, Ortho 9006, O,S-dimethyl ester
phosphoramidothioic acid, Tamaron.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Methamidophos Exposure:
Note: Methamidophos is a cholinesterase inhibitor.
Acute exposure to methamidophos may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur.
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EFATG
CAS Registry Number: 10265-92-6
Page 2 of 3
METHAMIDOPHOS
The heart rate may decrease following oral exposure or increase following
dermal exposure. Chest pain may be noted. Hypotension (low blood pressure)
may be noted, although hypertension (high blood pressure) is not uncommon.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
Emergency Life-Support Procedures:
Acute exposure to methamidophos may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methamidophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methamidophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
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EFATG
CAS Registry Number: 10265-92-6
Page 3 of 3
METHAMIDOPHOS
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of methamidophos is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of methamidophos may result in sudden onset of
seizures or loss of consciousness. Syrup of Ipecac should be
administered only if victims are alert, have an active gag-reflex, and
show no signs of impending seizure or coma. If ANY uncertainty exists,
proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 10294-34-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- BORON TRICHLORIDE
CAS Registry Number: 10294-34-5
Synonyms: Borane, Trichloro-; Boron Chloride; Boron Chloride [BC13];
Trichloroborane; Trichloroboron
Chemical Formula: BC13
Molecular Weight: 117.19
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(rat, mouse) 0.10 mg/liter/7 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 54.5°F, 12.5°C (*Merck 1976)
Specific Gravity (H2O=1): 1.35 at 12/4°C (*Merck 1976)
Vapor Pressure (mmHg): 760 at 12.7°C (*Sax 1979)
Melting Point: -161°F, -107°C (*Merck 1976)
Vapor Density (AIR=1): 4.03 (*Sax 1979)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Decomposes in water to form hydrogen chloride and
boric acid (Weast 1980, p. B62)
Appearance and Odor: Colorless, fuming liquid at low temperature (*Merck
1976) with a pungent, irritating odor (*Sax 1979)
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CAS Registry Number: 10294-34-5
Page 2 of 4
BORON TRICHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Rumack 1975 to Present)
Skin: Yes (*Rumack 1975 to Present)
Ingestion: Yes (*Rumack 1975 to Present)
Health Hazards (Acute, Delayed, and Chronic): Strong irritant to tissue.
Fumes are corrosive and highly toxic (*Hawley 1977). Boron affects the
central nervous system causing depression of circulation as well as shock
and coma. May cause severe burns to skin. May result in marked fluid and
electrolyte loss and shock (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: It is not flammable (Weiss 1980, p. 171). Use dry
chemical, carbon dioxide, or dry sand to extinguish. If large quantities
of combustibles are involved, use water in flooding quantities as spray and
fog. Use water spray to absorb vapors (Student 1981, p. 74). For large
fires use water spray, fog, or foam (DOT 1984, Guide 15). Do not get water on
material itself (Student 1981, p. 74).
Special Fire Fighting Procedures: Cool all affected containers with
flooding quantities of water. Apply water from as far a distance as
possible (Student 1981, p. 74). Do not get water inside container. Move
container from fire area if you can do so without risk. Stay away from
ends of tanks. Spray cooling water on containers that are exposed to
flames until well after fire is out. Isolate area until gas has dispersed
(DOT 1984, Guide 15).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes. It will react with water or steam to produce heat, and
toxic and corrosive fumes (*Sax 1979).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 10294-34-5
Page 3 of 4
BORON TRICHLORIDE
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 171)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Avoid aniline,
hexafluorisopropylidene amino lithium, nitrogen dioxide, phosphine, grease,
organic matter, and oxygen (Sax 1984, p. 514). Nitrogen peroxide,
phosphine, fat or grease react energetically with boron trichloride (*NFPA
1978). It will react with water or steam to produce heat, and toxic and
corrosive fumes (*Sax 1979). Oxygen and boron trichloride react vigorously
on sparking (*NFPA, 1978). Boron trichloride and aniline react violently
in the absence of a coolant or diluent (*Bretherick 1979).
Hazardous Decomposition or Byproducts: In hot water, decomposes to
hydrochloric acid and boric acid (*Weast 1979). Fumes and hydrolyzes in
moist air to form hydrochloric acid and oily, irritating corrosives (*Encyc
Occupat Health and Safety 1971). When heated to decomposition, emits toxic
fumes of chlorides (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Manufacture and purification of boron; catalyst in organic reactions;
semi-conductors; bonding of iron or steel; purification of metal alloys to
remove oxides, nitrides, and carbides (*Merck 1983); chemical intermediate
for boron filaments (*SRI); soldering flux; electrical resistors; and
extinguishing magnesium fires in heat treating furnaces (*Hawley 1977)
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep material out of water sources and sewers. Build dikes to contain flow
as necessary. Use water spray to knock down vapors. Do not use water on
material itself. Neutralize spilled material with crushed limestone, soda
ash or lime. Avoid breathing vapors. Keep upwind. Avoid bodily contact
with the material. Do not handle broken packages without protective
equipment. Wash away any material which may have contacted the body
with copious amounts of water or soap and water (Student 1981, p. 74).
Stop leak if you can do so without risk. Small spills: Flush area with
flooding amounts of water. Large spills: Dike far ahead of spill for
later disposal. Do not get water inside container. Isolate area until gas
has dispersed (DOT 1984, Guide 15).
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CAS Registry Number: 10294-34-5
Page 4 of 4
BORON TRICHLORIDE
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
CPE GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 10294-34-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
BORON TRICHLORIDE
(10294-34-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless liquid.
Odor - Pungent, irritating.
Commercial Form - 99% pure liquid, shipped in 50-pound pressure cylinders or
tank cars.
Uses - Manufacture and purification of boron, semiconductors, electrical
resistors, and metal alloys; iron bonding; catalyst; soldering flux;
extinguishing magnesium fires.
Materials to Avoid - Oxygen, water (except for use in emergency life support).
Caution: Avoid sources of heat including fire. Boron trichloride will
liberate toxic and corrosive fumes when heated to decomposition and will
generate hydrochloric acid upon contact with water.
Other Names - Trichloroborane, trichloroboron.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, normal saline, D5W,
Ringer's lactate.
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EFATG
CAS Registry Number: 10294-34-5
Page 2 of 3
BORON TRICHLORIDE
Signs and Symptoms of Acute Boron Trichloride Exposure:
Warning: Boron trichloride is extremely corrosive. Caution is advised.
Signs and symptoms of acute ingestion of boron trichloride may be severe and
include salivation, intense thirst, difficulty in swallowing, chills, pain, and
shock. Oral, esophageal, and stomach burns are common. Vomitus generally has
a coffee-ground appearance. The potential for circulatory collapse is high
following ingestion of boron trichloride.
Acute inhalation exposure of boron trichloride may result in sneezing,
hoarseness, choking, laryngitis, and respiratory tract irritation. Bleeding of
nose and gums, ulceration of the nasal and oral mucosa, bronchitis, pneumonia,
dyspnea (shortness of breath), chest pain, and pulmonary edema may also occur.
If the eyes have come in contact with boron trichloride, irritation, pain,
swelling, corneal erosion, and blindness may result. Dermal exposure may
result in dermatitis (red, inflamed skin), severe burns, and pain.
Emergency Life-Support Procedures:
Acute exposure to boron trichloride may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to boron trichloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
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CAS Registry Number: 10294-34-5
Page 3 of 3
BORON TRICHLORIDE
Dermal/Eye Exposure:
1. Remove victims from exposure.* Emergency personnel should avoid self-
exposure to boron trichloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Rinse mouth with large amounts of water. Inform victims not to swallow
this water.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
7. RUSH to a health care facility.
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CAS Registry Number: 10311-84-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DIALIFOR
CAS Registry Number: 10311-84-9
Synonyms: Phosphorodithioic Acid, S-(2-Chloro-l-(l,3-Dihydro-l,3-Dioxo-2H-
Isoindol-2-yl)Ethyl) O,O-Diethyl Ester; Dialifos; Dialiphor; ENT 27320;
Hercules 14503; O,O-Diethyl S-(2-chloro-l-phthalimidoethyl) Phosphorodithioate;
Phosphorodithioic acid, O,O-Diethyl Ester, S-Ester with N-(2-Chloro-l-
Mercaptoethyl)Phthalimide; Phosphorodithioic acid, S-(2-chloro-l-
phthalimidoethyl) O,O-Diethyl Ester; S-(2-chloro-l-(l,3-Dihydro-l,3-Dioxo-2H-
Isoindol-2-yl)Ethyl) O,O-Diethyl Phosphorodithioate; S-(2-chloro-l-
Phthalimidoethyl) O,O-Diethyl Phosphorodithioate; Torak
Chemical Formula: C14H17C1NO4PS2
Molecular Weight: 393.84
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.001 at 35°C (Worthing 1983, p. 168)
Melting Point: 153-156°F, 67-69°C solid; 144-147°F, 62-64°C
recrystallized from toluene and hexane (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
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CAS Registry Number: 10311-84-9
Page 2 of 4
DIALIFOR
SECTION II (continued)
Solubility in Water: Insoluble (*Merck 1976)
Appearance and Odor: White crystalline solid, also reported as oil
(*Merck 1976), colorless (*Worthing 1979)
SECTION III » HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 2216)
Ingestion: Yes (Sax 1984, p. 2216)
Health Hazards (Acute, Delayed, and Chronic): This material can cause
serious symptoms and in extreme cases death by respiratory arrest
(*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Solid, n.o.s.) This material may burn but does not ignite readily. Small
fires: dry chemical, carbon dioxide, water spray, or foam. Large fires:
water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Solid, n.o.s.) Stay upwind; keep out of low areas. Ventilate
closed spaces before entering them. Wear positive pressure breathing
apparatus and special protective clothing. Move container from fire area
if you can do it without risk. Fight fire from maximum distance. Dike
fire control water for later disposal; do not scatter the material (DOT
1984, Guide 55).
Unusual Fire and Explosion Hazards: Releases nitrogen oxides, sulfur
oxides, and phosphorus oxides when heated (Sax 1984, p. 2216)
NFPA Flammability Rating: Not Found
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CAS Registry Number: 10311-84-9
Page 3 of 4
DIALIFOR
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Hydrolyzed by concentrated alkali (*Worthing
1979)
Incompatibility (Materials to Avoid): Readily hydrolyzed by concentrated
alkali (*Worthing 1979)
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of sulfur oxides, nitrogen oxides, and phosphorus oxides
(Sax 1984, p. 2216)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is a non-systemic insecticide and acaricide (kills beetles,
ticks, mites, etc.), effective in controlling many insects and mites common
to apples, citrus, grapes, nut trees, potatoes, and vegetables (*Worthing
1979).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, Solid, n.o.s.) Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do it without risk. Use water spray to
reduce vapors. Small spills: take up with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 10311-84-9
Page 4 of 4
DIALIFOR
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Similar to parathion. Symptoms include
muscle weakness and twitching, fluid in lungs, nausea, vomiting, stomach
cramps, diarrhea, excessive salivation, headache, giddiness, dizziness,
tightness in chest, blurring or dimness of vision, tears, constriction of
pupils, loss of muscle coordination, slurring of speech, mental confusion,
disorientation and drowsiness, difficulty with breathing, convulsions, and
coma (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphorus
Pesticide, Solid, n.o.s.) Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 10476-95-6
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHACROLEIN DIACETATE
CAS Registry Number: 10476-95-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 331) 2-Propene-l,l-
Diol, 2-Methyl-, Diacetate; Acetic Acid, 2-Methyl-2-Propene-l,l-Diol Diester
Chemical Formula: C8H12O4
Molecular Weight: 172.20
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 skin
(rabbit) 44 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 191°C at 760 mmHg (Aldrich 1986, p.190)
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
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CAS Registry Number: 10476-95-6
Page 2 of 3
METHACROLEIN DIACETATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 84)
Skin: Yes (Sax 1984, p. 84)
Ingestion: Yes (Sax 1984, p. 84)
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits acrid smoke and irritating fumes (Sax 1984, p. 84).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits acrid smoke and irritating fumes (Sax 1984, p. 84).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 10476-95-6
Page 3 of 3
METHACROLEIN DIACETATE
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
DOT 1984
NFPA 1978
Encyc Occupat Health and Safety 1983
Student 1981
Weiss 1980
CHRIS 1978
Clayton and Clayton 1981-82
Arena 1979
Buchel 1983
Gosselin 1984
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Doull 1980
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CAS Registry Number: 12002-03-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PARIS GREEN
CAS Registry Number: 12002-03-8
Synonyms: Copper, bis(Acetato)Hexametaarsenitotetra-; (Acetato)
Trimetaarsenitodicopper; (Acetato-O)(Trimetaarsenito)Dicopper; Basle Green; CI
77410; CI Pigment Green 21; Copper Acetate Arsenite; Copper Aceto-Arsenite;
Copper (II) Acetate Meta-Arsenite; Cupric Acetoarsenite; Emerald Green; ENT
884; French Green; Genuine Paris Green; Imperial Green; King's Green; Meadow
Green; Mineral Green; Mitis Green; Moss Green; Mountain Green; Neuwied Green;
New Green; Ortho P-G Bait; Parrot Green; Patent Green; Powder Green;
Schweinfurt Green; Schweinfurtergrun; Schweinfurth Green; Sowbug and Cutworm
Bait; Sowbug Cutworm Control; Swedish Green; Vienna Green; Wuerzberg Green;
Zwickau Green
Chemical Formula: Complex Composition (*Gosselin 1984); Specifications
usually require approximately C4H6As6Cu4O16 (*Spencer 1982)
Molecular Weight: For Chemical Formula (usually contains some water):
1013.78 (NIOSH/RTECS 1983, p. 958)
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
22 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 100 (pounds) (statutory); 1 (pounds) (proposed)
Section 313 Listed (Yes or No): In Arsenic Compounds and Copper
Compounds categories
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes (Weiss 1980, p. 265)
Specific Gravity (H2O=1): Estimated as greater than 1.1 at 68°F, 20°C
(*CHRIS 1978)
Vapor Pressure (mmHg): Not Found
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CAS Registry Number: 12002-03-8
Page 2 of 4
PARIS GREEN
SECTION II (continued)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Weast 1983)
Appearance and Odor: Emerald green, crystalline powder (*Merck 1983);
odorless (*CHRIS 1978)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: (Arsenic and compounds) TWA 0.01 mg/m3, as arsenic (NIOSH 1987,
P-54)
ACGIH TLV: (Arsenic and soluble compounds) 0.2 mg/m3, as arsenic (ACGIH
1986-87, p. 10)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Morgan 1976)
Skin: Yes (*Morgan 1976)
Ingestion: Yes (*Morgan 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7
drops and 1 teaspoonful for a 150-lb. person (*Gosselin 1984). Some
absorption may occur through the skin and by inhalation, but most
poisonings result from ingestion (*Morgan 1976). It may cause eye and
respiratory tract irritation (*Grant 1974). Industrial exposure may cause
dermatitis (*Hayes 1982).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (Weiss 1980, p. 265)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, water spray, or
foam. For large fires, use water spray, fog, or foam (DOT 1984, Guide 53).
Use of water may result in generation of toxic fumes (see Section IV
below).
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CAS Registry Number: 12002-03-8
Page 3 of 4
PARIS GREEN
SECTION IV (continued)
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear self-contained (positive pressure if available) breathing apparatus
and full protective clothing (DOT 1984, Guide 53).
Unusual Fire and Explosion Hazards: Poisonous, volatile arsenic oxide may
be formed in fires (*CHRIS 1978). Exposure of dust to flame may cause
explosion (*Rumack 1975 to Present).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1983)
Conditions to Avoid: Unstable in acids and bases (*Merck 1983)
Incompatibility (Materials to Avoid): Can react vigorously with oxidizing
materials. Emits highly toxic fumes on contact with acid or acid fumes
(*Sax 1975).
Hazardous Decomposition or Byproducts: When heated, it emits highly toxic
fumes (*Sax 1975); decomposes readily in the presence of waterand carbon
dioxide to yield phytotoxic arsenical compounds (*Spencer 1982).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 265)
Condit'ons to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used primarily as an insecticide (*Clarke 1981); it may be
used as a wood preservative and a pigment, particularly for ships and
submarines (*Merck 1983), and also finds use as an anthelmintic (*Rossoff,
1974).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Stay upwind; keep out of low areas. Do not touch spilled material.
Take up small spills with sand or other noncombustible absorbent
material and place into containers for later disposal. For small
dry spills, use clean shovel to place material in clean, dry container.
For large spills, dike far ahead of spill for later disposal
(DOT 1984, Guide 53). Use water spray to knock down dust (Weiss
1980, p. 265).
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CAS Registry Number: 12002-03-8
Page 4 of 4
PARIS GREEN
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms usually appear 1/2 to 1 hour
after ingestion, but may be delayed. Symptoms include a sweetish, metallic
taste and garlicky odor; difficulty in swallowing; abdominal pain; vomiting
and diarrhea; dehydration; rapid heart beat; dizziness and headache; and
eventually coma, sometimes convulsions, and death (*Gosselin 1984).
Emergency and First Aid Procedures: Remove contaminated clothing and
shoes. For ingestion, give copious quantities of water and induce repeated
vomiting. If eyes have been exposed, flush with water for 15 minutes. If
there has been skin contact, wash thoroughly with soap and water (Weiss
1980, p. 265).
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CAS Registry Number: 12108-13-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - MANGANESE, TRICARBONYL METHYLCYCLOPENTADIENYL
CAS Registry Number: 12108-13-3
Synonyms: Methylcyclopentadienyl Manganese Tricarbonyl;
(Methylcyclopentadienyl)Manganese Tricarbonyl; (Methylcyclo-
pentadienyl)Tricarbonylmanganese; 2-Methylcyclopentadienylmanganese
Tricarbonyl; AK-33X; Antiknock-33; CI-2; Combustion Improver-2; Manganese,
Tricarbonyl((l,2,3,4,5-eta)-l-Methyl-2,4-Cyclopentadien-l-yl)-; Manganese,
Tricarbonyl(Methyl-pi-Cyclopentadienyl)-; Methylcymantrene; MMT; pi-Methyl-
cyclopentadienylmanganese Tricarbonyl; Tricarbonyl(2-Methylcyclopentadienyl)
Manganese; Tricarbonyl(eta(5)-Methylcyclopentadienyl)Manganese; Tricarbonyl
(Methyl-pi-Cyclopentadienyl)Manganese; Tricarbonyl(Methylcyclopentadienyl)
Manganese
Chemical Formula: C9H7MnOs
Molecular Weight: 218.10
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.059 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Manganese Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 449°F, 232°C (*ACGIH 1980)
Specific Gravity (H2O=1): 1.39 at 20°C (*ACGIH 1980)
Vapor Pressure (mmHg): 7.3 at 100°C (*ACGIH 1980)
Melting Point: 34°F, 1°C (Weiss 1980, p. 607)
Vapor Density (AIR=1): Not Found
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CAS Registry Number: 12108-13-3
Page 2 of 4
MANGANESE, TRICARBONYL METHYLCYCLOPENTADIENYL
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*ACGIH 1980)
Appearance and Odor: A dark orange liquid with a faintly pleasant smell
(*ACGIH 1980).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Manganese compounds) Ceiling 5 mg/m5, as manganese (NIOSH 1987,
p. 150)
ACGIH TLV: TWA 0.1 mg/ms, as manganese (skin) (ACGIH 1986-87, p. 22)
- IDLH: (Manganese compounds) 10,000 mg/ms, as manganese (NIOSH 1987,
p. 150)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*ACGIH 1980)
Skin: Yes (*ACGIH 1980)
Ingestion: Yes (*ACGIH 1980)
Health Hazards (Acute, Delayed, and Chronic): In concentrated form this
compound is highly toxic by all routes of exposure. Approximately 5-15 ml,
when spilled on the hand and wrist of a worker, produced toxic effects
within 3-5 minutes (*ACGIH 1980).
Medical Conditions Generally Ag^iavated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 230°F, 110°C (CC) (*ACGIH 1980)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Extinguish with water, dry chemicals, foam, or
carbon dioxide. Wear goggles and self-contained breathing apparatus (Weiss
1980, p. 607).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, this
compound emits toxic fumes of carbon monoxide (Sax 1984, p. 1733).
NFPA Flammability Rating: Not Found
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CAS Registry Number: 12108-13-3
Page 3 of 4
MANGANESE, TRICARBONYL METHYLCYCLOPENTADIENYL
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 607)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits carbon monoxide when heated
to decomposition (Sax 1984, p. 1733).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 607)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This compound is used as a smoke abater additive in fuels (*ACGIH 1980), a
gasoline additive in antiknock mixes, and a combustion improver in
distillate fuels and fuel oils (*SRI).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Stop discharge, if possible; isolate and remove discharged material (Weiss
1980, p. 607). Large spills can be cleaned up using JP-4L or
JP-5 (jet engine fuels). Isopropyl alcohol may be used to clean up
moderate spills, while methyl ethyl ketone should be used for cleaning
small spills and quick disconnects (*ACGIH 1980). Avoid contact with
liquid; keep people away. Call fire department and notify local health
and pollution control agencies (Weiss 1980, p. 607).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This compound is moderately irritating to
the eyes. Giddiness, "thick tongue," nausea, and headache were reported to
occur after skin exposure. Human exposure data are limited; the primary
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CAS Registry Number: 12108-13-3
Page 4 of 4
MANGANESE, TRICARBONYL METHYLCYCLOPENTADIENYL
SECTION IX (continued)
site of action is reported to be the central nervous system (ACGIH 1980, p.
272).
Emergency and First Aid Procedures: Remove victim from exposure. Exposed
clothing should be removed, and exposed areas of the body should be washed
twice with soap and water. If eyes are exposed flush with copious amounts
of water for at least 15 minutes. Induce vomiting unless patient is
comatose, convulsing, or has lost gag reflex. Get medical attention
following all exposures to this compound (Weiss 1980, p. 607; *Rumack 1975
to Present).
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CAS Registry Number: 13071-79-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ TERBUFOS
CAS Registry Number: 13071-79-9
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 141): Phosphorodithioic
Acid, O,O-Diethyl-S-(((l,l-Dimethylethyl)thio)Methyl)-Ester; AC 92100;
S-((Tert-Butylthio)Methyl)O,O-Diethylphosphorodithioate; Counter; Counter 15G
Soil Insecticide; S-((( 1,1 -Dimethylethyl)Thio)Methyl)-O,O-Diethy 1
Phosphorodithioate; Phosphorodithioic Acid S-((Tert-Butylthio)Methyl)
O,O-Diethyl Ester; Phosphorodithioic Acid S-(((l,l-Dimethylethyl)Thio)Methyl)
O,O-Diethyl Ester
Chemical Formula: C9H21O2PS3
Molecular Weight: 288.45
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
1.6 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 156°F, 69°C at 0.01 mmHg (Merck 1983, p. 1310)
Specific Gravity (H2O=1): 1.105 at 24°C (Merck 1983, p. 1310)
Vapor Pressure (mmHg): 0.0003 mmHg at 25°C (Worthing 1983, p. 512)
Melting Point: -20.6°F, -29.2°C (Merck 1983, p. 1310)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 15 ppm (Farm Chemicals Handbook 1978, p. C62)
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CAS Registry Number: 13071-79-9
Page 2 of 4
TERBUFOS
SECTION II (continued)
Appearance and Odor: Technical product: clear, colorless to pale yellow
liquid (Merck 1983, p. 1310).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Farm Chemicals Handbook 1984, p. C62)
Skin: Yes (Farm Chemicals Handbook 1984, p. C62)
Ingestion: Yes (Farm Chemicals Handbook 1984, p. C62)
Health Hazards (Acute, Delayed, and Chronic): This material may be fatal
if swallowed, inhaled, or absorbed through the skin. Repeated inhalation
or skin contact may progressively increase susceptibility to poisoning
(Farm Chemicals Handbook 1984, p. C62).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 190°F, 88°C (TOC) (Merck 1983, p. 1310)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is a liquid organophosphorus pesticide (Encyc
Occupat Health and Safety 1983, p. 1620). For small fires, use dry
chemical, carbon dioxide, water spray, or foam. For large fires, use water
spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This is a liquid organophosphorus
pesticide (Encyc Occupat Health and Safety 1983, p. 1620). Wear positive
pressure breathing apparatus and special protective clothing. Move
container from fire area if you can do so without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: This is a liquid organophosphorus
pesticide (Encyc Occupat Health and Safety 1983, p. 1620). Fire may
produce irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 13071-79-9
Page 3 of 4
TERBUFOS
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Farm Chemicals Handbook 1984, p. C62)
Conditions to Avoid: Hydrolyzes under alkaline conditions (Farm
Chemicals Handbook 1984, p. C62).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material is used as a soil insecticide (Merck 1983, p. 1310).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is a liquid organophosphorus pesticide (Encyc Occupat Health and
Safety 1983, p. 1620). Keep unnecessary people away; isolate hazard area
and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Remove and isolate contaminated clothing
at the site. Do not touch spilled material; stop leak if you can do so
without risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 13071-79-9
Page 4 of 4
TERBUFOS
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 13071-79-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
TERBUFOS
(13071-79-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Clear, colorless liquid.
Commercial Form - Pale yellow liquid.
Use - Insecticide.
Other Names - AC 92100; Counter; S-((tert-butylthio)methyl) O,O-
diethylphosphorodithioate.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Supp ,rt Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Terbufos Exposure:
Note: Terbufos is a cholinesterase inhibitor.
Acute exposure to terbufos may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may decrease following oral exposure or increase
following dermal exposure. Chest pain may be noted. Hypotension (low blood
pressure) may be noted, although hypertension (high blood pressure) is not
uncommon. Respiratory symptoms include dyspnea (shortness of breath),
respiratory depression, and respiratory paralysis. Psychosis may occur.
-------
EFATG
CAS Registry Number: 13071-79-9
Page 2 of 3
TERBUFOS
Emergency Life-Support Procedures:
Acute exposure to terbufos may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to terbufos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to terbufos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 13071-79-9
Page 3 of 3
TERBUFOS
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of terbufos is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of terbufos may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 13171-21-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHAMIDON
CAS Registry Number: 13171-21-6
Synonyms: Phosphoric Acid, Dimethyl Ester, Ester with 2-Chloro-N,N-
Diethyl-3-Hydroxycrotonamide; l-Chloro-Diethylcarbamoyl-l-Propen-2-yl Dimethyl
Phosphate; 2-(N,N-Diethylcarbamoyl)-l-Methylvinyl Phosphate; 2-Chloro-2-
Diethylcarbamoyl-1-Methyl vinyl Dimethyl Phosphate; 2-Chloro-2-Diethylcarbamyl-
1-Methylvinyl Dimethyl Phosphate; 2-Chloro-3-(Diethylamino)-l-Methyl-3-Oxo-l-
Propenyl Dimethyl Phosphate; 2-Chloro-N,N-Diethyl-3-Hydroxycrotonamide Dimethyl
Phosphate; Crotonamide, 2-Chloro-N,N-Diethyl-3-Hydroxy-, Dimethyl Phosphate;
Dimecron; Dimecron 100; Dimecron 50; Dimecron-20; Dimethyl Phosphate of
2-Chloro-N,N-Diethyl-3-Hydroxycrotonamide; Dixon; Famfos; Merkon; N,N-Diethyl
2-Chloro-3-Dimethylphosphate Crotonamide; NCI-C0058; Phosphamidone; Phosphoric
Acid, 2-Chloro-3-(Diethylamino)-l-Methyl-3-Oxo-l-Propenyl Dimethyl Ester;
Sundaram 1975
Chemical Formula: C10H19C1NO6P
Molecular Weight: 299.70
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.03 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 324°F, 162°C at 1.5 mmHg (*Martin and Worthing 1974)
Specific Gravity (H2O=1): 1.2132 at 25°C/4°C (*Martin and Worthing 1974)
Vapor Pressure (mmHg): 0.000025 at 20°C (*Martin and Worthing 1974)
Melting Point: -49°F, -45°C (*Merck 1976)
-------
CAS Registry Number: 13171-21-6
Page 2 of 4
PHOSPHAMIDON
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Miscible (*Merck 1976)
Appearance and Odor: Pale yellow oily liquid (*Farm Chemicals Handbook
1975), faint odor (*Martin and Worthing 1974).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: ADI in connection with residues of pesticides
in foods -- 0.001 mg/kg (*Hayes 1975).
Routes of Entry: Inhalation: Yes (*Hawley 1977)
Skin: Yes (*Hawley 1977)
Ingestion: Yes (*Hawley 1977)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7
drops and 1 teaspoonful for a 150-lb person (*Gosselin 1976). It is a
cholinesterase inhibitor (*Hawley 1977).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn, but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific - Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move
containers from fire area if you can do it without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
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CAS Registry Number: 13171-21-6
Page 3 of 4
PHOSPHAMIDON
SECTION IV (continued)
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire (DOT
1984, Guide 55). Heat may cause decomposition and evolution of highly
toxic fumes of phosphorus oxides and chlorides (*Sax 1975).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes, in neutral and acid media (*Martin
and Worthing 1974)
Conditions to Avoid: Hydrolyzes in alkali (*Martin and Worthing
1974).
Incompatibility (Materials to Avoid): Hydrolyzes in alkali (*Martin and
Worthing 1974)
Hazardous Decomposition or Byproducts: Decomposes above 320°F, 160°C
(*Sunshine 1969); may emit highly toxic fumes of phosphorus oxides and
chlorides (*Sax 1975).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
This material is an insecticide for citrus, cotton, and deciduous fruit and
nuts (*SRI). It is also an acaricide (*Farm Chemicals Handbook 1980).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Do
not touch spilled material; stop leak if you can do so without risk. Use
water spray to reduce vapors. Small spills: absorb with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
-------
CAS Registry Number: 13171-21-6
Page 4 of 4
PHOSPHAMIDON
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 13171-21-6
Page 1 of 4
Emergency First Aid Treatment Guide
for
PHOSPHAMIDON
(13171-21-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless to pale yellow liquid.
Odor - Faint.
Commercial Form - Pale yellow, oily liquid.
Use - Pesticide.
Caution: Explosion potential is high. Containers may explode in heat of fire.
Highly toxic phosphorus oxides and chlorides may be emitted when phosphamidon
is heated to decomposition. Avoid sources of extreme heat.
Other Names - Apamidon, 2-chloro-2-diethylcarbamoyl-l-methylvinyl dimethyl
phosphate, Ciba 570, Dimecron, Dixon, Famfos, Merkon, Sundaram 1975.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
-------
EFATG
CAS Registry Number: 13171-21-6
Page 2 of 4
PHOSPHAMIDON
Signs and Symptoms of Acute Phosphamidon Exposure:
Note: Phosphamidon is a cholinesterase inhibitor.
Acute exposure to phosphamidon may produce pinpoint pupils, blurred vision,
headache, dizziness, muscle spasms, and profound weakness. Vomiting, diarrhea,
abdominal pain, seizures, and coma may also occur. The heart rate may decrease
following oral exposure or increase following dermal exposure. Hypotension
(low blood pressure) may occur, although hypertension (high blood pressure) is
not uncommon. Chest pain may be noted.
Respiratory effects include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
Emergency Life-Support Procedures:
Acute exposure to phosphamidon may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to phosphamidon.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to phosphamidon.
-------
EFATG
CAS Registry Number: 13171-21-6
Page 3 of 4
PHOSPHAMIDON
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of phosphamidon is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of phosphamidon may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
-------
EFATG
CAS Registry Number: 13171-21-6
Page 4 of 4
PHOSPHAMIDON
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 13194-48-4
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - ETHOPROPHOS
CAS Registry Number: 13194-48-4
Synonyms: Phosphorodithioic Acid, O-Ethyl S,S-DipropyI Ester; Mocap; ENT
27,318; Ethoprop; Jolt; O-Ethyl S,S-Dipropyl Dithiophosphate; O-Ethyl
S,S-Dipropyl Phosphorodithioate; O-Ethyl S,S-Dipropylphosphorodithioate;
Prophos; Rovokil; V-C Chemical V-C 9-104; VC 9-104; VC9-104
Chemical Formula: C8H19O2PS2
Molecular Weight: 242.36
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 dermal
(rabbit) 26 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 187-196°F, 86-91°C at 0.2 mmHg (*Worthing 1979)
Specific Gravity (H2O=1): 1.094 at 20°C (*Worthing 1979)
Vapor Pressure (mmHg): 0.00035 at 26°C (*Worthing 1979)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 750 mg/liter (*Worthing 1979)
Appearance and Odor: Clear, pale yellow liquid (*Worthing 1979).
-------
CAS Registry Number: 13194-48-4
Page 2 of 4
ETHOPROPHOS
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): This material is extremely
toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7
drops and 1 teaspoonful for a 150 Ib. person. It is a cholinesterase
inhibitor which affects the nervous system (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move
containers from fire area if you can do it without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire
and runoff from fire control water may produce irritating or poisonous
gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes, in water (*Worthing 1979)
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CAS Registry Number: 13194-48-4
Page 3 of 4
ETHOPROPHOS
SECTION V (continued)
Conditions to Avoid: Hydrolyzed in alkali (*Worthing 1979).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide and nematocide on a number of crops
(*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Do
not touch spilled material; stop leak if you can do it without risk. Use
water spray to reduce vapors. Small spills: take up with sand or other
noncombustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 13194-48-4
Page 4 of 4
ETHOPROPHOS
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms are similar to parathion and may
include nausea, vomiting, abdominal cramps, diarrhea, excessive salivation,
headache, giddiness, weakness, muscle twitching, difficult breathing,
blurring or dimness of vision, and loss of muscle coordination. Death may
occur from failure of the respiratory center, paralysis of the respiratory
muscles, intense bronchoconstriction, or all three (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific -- Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
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CAS Registry Number: 13410-01-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - SODIUM SELENATE
CAS Registry Number: 13410-01-0
Synonyms: (NIOSH/RTECS 1983 SYNONYMS, VOLUME 3, p. 580) Selenic Acid,
Disodium Salt; Disodium Selenate; P-40; Sel-Tox SS02 and SS-20; Selenic Acid
(H2SeO4), Disodium Salt
Chemical Formula: Na2SeO4
Molecular Weight: 188.94
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
2.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Selenium Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 3.098 (Sax 1984, p. 1254)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (Merck 1983, p. 1241)
Appearance and Odor: Colorless rhombic crystals (Sax 1984, p. 1254)
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CAS Registry Number: 13410-01-0
Page 2 of 4
SODIUM SELENATE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Selenium compounds) 0.2 mg/m3, as selenium (NIOSH 1987, p.206)
ACGIH TLV: (Selenium compounds) TWA 0.2 mg/m3, as selenium (ACGIH 1986-87,
P. 29)
IDLH: Not Found
Other Limits Recommended: IDLH for selenium compounds 100 mg/m3, as
selenium (NIOSH 1987, p. 206)
Routes of Entry: Inhalation: Yes (DOT 1984, Guide 53)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1254)
Health Hazards (Acute, Delayed, and Chronic): Causes damage to liver and
kidneys. Resembles arsenic in its effects (Sax 1984, p. 1254).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Dry chemical, carbon dioxide, water spray, fog, or
foam. Move container from fire area if it can be done without risk (DOT
1984, Guide 53).
Special Fire Fighting Procedures: Stay upwind; keep out of low areas.
Wear self-contained (positive pressure if available) breathing apparatus
and full protective clothing (DOT 1984, Guide 53).
. Unusual Fire and Explosion Hazards: Fire may produce irritating or
poisonous gas (DOT 1984, Guide 53).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposing heat (Sax 1984, p. 1254)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits toxic selenium and sodium
oxide fumes when heated to decomposition (Sax 1984, p. 1254).
-------
CAS Registry Number: 13410-01-0
Page 3 of 4
SODIUM SELENATE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Insecticide in some horticultural applications (Merck 1983, p. 1241).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid breathing dust (see Section III above). Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills:
with clean shovel place material into clean, dry container and cover;
move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 53).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
ohemical resistant suit. See the introductory information section at the
Beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Selenium Compounds)
Garlic odor of breath is common. Pallor, nervousness, depression, and
digestive disturbances. Inorganic selenium compounds can cause dermatitis
(Sax 1984, p. 2390).
-------
CAS Registry Number: 13410-01-0
Page 4 of 4
SODIUM SELENATE
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air. Remove
contaminated clothing and shoes at site. In case of contact, immediately
flush skin or eyes with running water for at least 15 minutes (DOT 1984,
Guide 53).
-------
CAS Registry Number: 13450-90-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- GALLIUM TRICHLORIDE
CAS Registry Number: 13450-90-3
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 362) Gallium(3+)
Chloride
Chemical Formula: GaCl3
Molecular Weight: 176.07
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCJow inhalation
(rat) 0.191 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 394°F, 201.3°C (Weast 1978, p. B-119)
Specific Gravity (H2O=1): 2.47 at 25°C/4°C (Weast 1978, p. B-119)
Vapor Pressure (mmHg): Not Found
Melting Point: I72°F, 78°C (Sax 1984, p. 1470)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Very soluble (Weast 1978, p. B-119); very soluble in
either hot or cold water (Clayton and Clayton 1981-82, p. 1632)
Appearance and Odor: Colorless needles (Sax 1984, p. 1470)
-------
CAS Registry Number: 13450-90-3
Page 2 of 4
GALLIUM TRICHLORIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p.1470)
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific - Gallium
Compounds) In view of the toxicity of gallium and its compounds, as shown
by experiments, all persons involved in work with these substances should
-'undergo periodic medical examinations^ during which special attention
should be paid to the condition of the liver, respiratory organs, and
skin (Encyc Occupat Health and Safety 1983, pp. 938-939).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposes upon sufficient heating (Sax 1984, p.
1470)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits toxic chloride fumes when
heated to decomposition (Sax 1984, p. 1470)
-------
CAS Registry Number: 13450-90-3
Page 3 of 4
GALLIUM TRICHLORIDE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Used as a raw material in the production of metallic gallium (Hawley 1981,
p. 488); and in the processing of monocrystal semi-conductor compounds
(Encyc Occupat Health and Safety 1983, p. 938).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact.
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. Remove and
isolate contaminsted clothing and shoes at the site. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes (DOT 1984, Guide 53).
-------
CAS Registry Number: 13450-90-3
Page 4 of 4
GALLIUM TRICHLORIDE
COMMENTS
Other sources checked but no information found:
ACGIH 1983
Merck 1983
DASE 1980
NIOSH/OSHA 1978
Hayes 1982
Doull 1980
Gosselin 1984
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
Farm Chemicals Handbook 1984
Verschueren 1983
-------
CAS Registry Number: 13463-39-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- NICKEL CARBONYL
CAS Registry Number: 13463-39-3
Synonyms: Nickel Carbonyl [Ni(CO)4], (T-4)-; Nickel
Tetracarbonyl; Tetracarbonyl Nickel; UN 1259
Chemical Formula: C4NiO4
Molecular Weight: 170.75
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.067 mg/liter/30 minutes (*NIOSH/RTECS 1985)
TPQ: 1 (pounds)
RQ: 1 (pounds) (statutory); 10 (pounds) (proposed)
Section 313 Listed (Yes or No): In Nickel Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 109°F, 43°C (*Merck 1983)
Specific Gravity (H2O=1): 1.318 at 17°C (*Merck 1983)
Vapor Pressure (mmHg): 400 at 25.8°C (*Hawley 1981)
Melting Point: -2.2°F, -19.3°C (*Merck 1983)
Vapor Density (AIR=1): 5.89 (NFPA 1984, p. 325M-74)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Soluble in about 5000 parts water free from air
(*Merck 1983)
Appearance and Odor: Nickel carbonyl exists as a gas or as a colorless
liquid (*Merck 1983; *Hamilton and Hardy 1974). It has a peculiar sooty
odor (*Clayton and Clayton 1982).
-------
CAS Registry Number: 13463-39-3
Page 2 of 4
NICKEL CARBONYL
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.007 mg/ms (0.001 ppm) (NIOSH 1987, p. 172)
ACGIH TLV: TWA 0.35 mg/ms (0.05 ppm), as nickel (*ACGIH 1983)
IDLH: 0.001 ppm (NIOSH/OSHA 1978, p. 138)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*DOT 1984)
Skin: Yes (*DOT 1984)
Ingestion: Yes (*DOT 1984)
Health Hazards (Acute, Delayed, and Chronic): Probable oral lethal dose
for a human is between 50 and 500 mg/kg, between one teaspoon and one ounce
per 150 Ib. person (*Gosselin 1976). Nickel carbonyl has also been
estimated to be lethal in man at atmospheric exposures of 30 ppm for 20
minutes (*Doull 1980). Autopsies show congestion, collapse, and tissue
destruction, as well as hemorrhage in the brain (""Hamilton and Hardy 1974).
Dermatitis, recurrent asthmatic attacks, and increased number of white
blood cells (eosinophils) in respiratory tract are acute health hazards
(*DOT 1984). Nickel carbonyl is poisonous. It can be fatal if inhaled,
swallowed, or absorbed through skin. Vapors may cause irritation,
congestion, and edema of lungs (*Merck 1983).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Less than -18°C (no method given) (*NFPA 1978)
Flammable Limits: Flammable and burns with a yellow flame ('Clayton and
Clayton 1982)
LEL: 2% (NIOSH/OSHA 1978, p. 138)
UEL: Not Found
Extinguishing Methods: Use water, alcohol foam, carbon dioxide, dry
chemical (*NFPA 1978). Use water in flooding quantities as fog. Solid
streams of water may be ineffective (Student 1981, p. 363).
Special Fire Fighting Procedures: Material is too dangerous to health to
expose fire fighters. A few whiffs of the vapor could cause death. If
liquid or vapor penetrates fire fighter's protective gear it will cause
fatality. Normal full protective gear available to the average fire
department will not provide adequate inhalation or skin protection (*NFPA
1978).
Unusual Fire and Explosion Hazards: Vapor forms explosive mixtures with
air. Vapor is heavier than air and may travel a considerable distance to
source of ignition and flash back (*NFPA 1978). Liquid may explode when
heated under confinement (NFPA 1984, p. 49-66). Vapor explosion and poison
hazard indoors, outdoors, or in sewers. Runoff to sewer may create fire
and explosion (*DOT 1984).
-------
CAS Registry Number: 13463-39-3
Page 3 of 4
NICKEL CARBONYL
SECTION IV (continued)
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (Weiss 1980, p. 646)
Stable:
Conditions to Avoid: Contact with air (*Clayton and Clayton 1981-82).
Contact with heat, acid, or acid fumes (*Sax 1979). Ignition sources
and vapors entering a confined space (*NIOSH/OSHA 1981).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: May explode at 68°F (20°C) in
presence of air or oxygen (*Clayton and Clayton 1981-82). Emits highly
toxic fumes^when heated or on contact with acid or acid fumes (*Sax 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Nickel carbonyl is used to nickel-coat steel and other metals (Student
1981, p. 363). It is also used in the electronics industry (*Doull 1980).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Material is extremely dangerous and may explode. Do not inhale vapors or
allow material to contact skin (see Sections III, IV, and V above).
Remove all ignition sources. Ventilate area of spill. Atomize large
quantities in a combustion chamber equipped with an effluent gas cleaning
device. Nickel carbonyl should not be allowed to enter a confined space
(such as a sewer) because of the possibility of an explosion (*NIOSH/OSHA
1981). Isolate hazard area and deny entry. Stay upwind and out of low
areas. Do not touch spilled material; stop leak if you can do so without
risk. Use water spray to reduce vapors (*DOT 1984).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 13463-39-3
Page 4 of 4
NICKEL CARBONYL
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED*
CPE GOOD/LIMITED*
PVC GOOD/LIMITED*
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 13463-39-3
Page 1 of 3
Emergency First Aid Treatment Guide
for
NICKEL CARBONYL
(13463-39-3)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - Gas or colorless liquid.
Odor - Musty, irritating.
Commercial Form - Liquid in cylinders pressurized with carbon monoxide.
Uses - Electronics industry, nickel-coated metals, nickel powder.
Materials to Avoid - Oxidizers, acids, halogens.
Other Names - Nickel tetracarbonyl.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
dimercaprol, disulfiram, penicillamine.
Signs and Symptoms of Acute Nickel Carbonyl Exposure:
Warning: Effects usually occur in two stages: immediate and delayed. Delayed
effects may begin hours to days after exposure. Caution is advised.
Acute exposure to nickel carbonyl may result in dizziness, giddiness, weakness,
convulsions, hallucinations, delirium, nausea, vomiting, and diarrhea.
Following inhalation, respiration will initially be rapid, accompanied by a
nonproductive cough, and followed by pain and tightness in the chest.
-------
EFATG
CAS Registry Number: 13463-39-3
Page 2 of 3
NICKEL CARBONYL
Pulmonary edema, cerebral edema, and hepatic (liver) degeneration may also
occur. Vapor is irritating to the eyes, nose, and throat.
Nickel contact dermatitis is the most common reaction to nickel carbonyl.
Nickel itch may begin with a burning sensation and itching, often followed by
erythema (redness) and nodular eruptions. Liquid nickel carbonyl will burn the
skin and eyes.
Emergency Life-Support Procedures:
Acute exposure to nickel carbonyl may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
-supplied-air-respiratory - equipment' should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to nickel carbonyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. . RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to nickel carbonyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
-------
EFATG
CAS Registry Number: 13463-39-3
Page 3 of 3
NICKEL CARBONYL
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims
are conscious and alert.
4. Activated charcoal may be administej ;d if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for clmuren, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
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CAS Registry Number: 13463-40-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- IRON, PENTACARBONYL-
CAS Registry Number: 13463-40-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p.547-548) Iron Carbonyl;
Pentacarbonyliron
Chemical Formula: Fe(CO)6
Molecular Weight: 195.90
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LCBO inhalation
(rat) 0.044 mg/liter (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 216.8°F, 102.8°C at 749 mmHg (Weast 1979, p. B-126)
Specific Gravity (H2O=1): 1.457 at 21°C (Weast 1979, p. B-126)
Vapor Pressure (mmHg): 40 at 30.3°C (Sax 1984, p. 2125)
Melting Point: -5.8°F, -21°C (Weast 1979, p. B-126)
Vapor Density (AIR=1): 6.74 (NFPA 1984, p. 325M-60)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. B-126)
Appearance and Odor: Viscous yellow liquid (Weast 1979, p. B-126)
-------
CAS Registry Number: 13463-40-6
Page 2 of 4
IRON, PENTACARBONYL-
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 0.8 mg/ms (0.1 ppm); STEL 1.6 mg/m3 (0.2 ppm) (ACGIH 1985,
P. 21)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Hawley 1981, p. 572)
Skin: Yes (Hawley 1981, p. 572)
Ingestion: Yes (Hawley 1981, p. 572)
Health Hazards (Acute, Delayed, and Chronic): Toxicity of this compound
is high via all routes of entry. Cyanosis (bluish discoloration of skin)
-and circulatory collapse may occur after exposure. Death may result.
Pneumonitis and injury to the kidneys, liver, and central nervous system
may also occur (Merck 1983, p. 736; Sax 1984, p. 2125).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 5°F, -15°C (Hawley 1981, p. 572)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material is incompatible with water (Sax
1984, p. 2125). Use dry chemical, carbon dioxide, water spray, or foam for
small fires, and water spray, fog, or foam for large fires. Move material
from fire area if this can be done without risk. Dike fire control water
for later disposal (DOT 1984, Guide 28).
Special Fire Fighting Procedures: Isolate hazard area and deny entry.
Stay upwind and keep out of low areas. Isolate area for 1/2 mile in all
directions if tank car or truck is involved in fire. Wear positive
pressure breathing apparatus and special protective clothing. Cool
containers exposed to flames with water until fire is out. Withdraw
immediately in case of rising sound from venting safety device or any
discoloration of tank due to fire (DOT 1984, Guide 28).
Unusual Fire and Explosion Hazards: This material may be ignited by heat,
sparks, or flames. Vapors may travel to ignition source and flash back.
Containers may explode in the heat of fire. Evolution of carbon monoxide
may create a poison hazard. This material presents a vapor explosion and
poison hazard indoors, outdoors, or in sewers (DOT 1984, Guide 28).
NFPA Flammability Rating: 3
-------
CAS Registry Number: 13463-40-6
Page 3 of 4
IRON, PENTACARBONYL-
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Yes (Hawley 1981, p. 572)
Stable:
Conditions to Avoid: Decomposes in acids and alkalies (Hawley 1981,
p. 572). Protect from light and air (Merck 1983, p. 736).
Incompatibility (Materials to Avoid): Acetic acid, water, nitrogen oxide,
transition metal halides, and zinc (Sax 1984, p. 2125), and it burns in air
(Merck 1983, p. 736).
Hazardous Decomposition or Byproducts: Evolves carbon monoxide on
exposure to air or to light (Hawley 1981, p. 572). Emits carbon monoxide
when heated to decomposition (Sax 1984, p. 2125).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Iron carbonyl is used as a catalyst in organic reactions; to make carbonyl
iron which is used in high frequency coils for the radio and television
industry; and as an anti-knock agent in motor fuels (Merck 1983, p. 736).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not breathe vapors (see Section III above). Shut off or remove
ignition sources in hazard area. Do not touch spilled material. Stop leak
if this can be done without risk. Use water spray to reduce vapors. Take
up small spills with sand or other noncombustible absorbent material and
place into containers for later disposal. Dike far ahead of large spills
for later disposal (DOT 1984, Guide 28).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Inhalation may result in dizziness,
nausea, and vomiting; if exposure continues, unconsciousness will follow.
Delayed reactions include chest pain, cough, and difficult breathing (Sax
1984, p. 2125).
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CAS Registry Number: 13463-40-6
Page 4 of 4
IRON, PENTACARBONYL-
SECTION IX (continued)
Emergency and First Aid Procedures: Move victim to fresh air and call
emergency medical care. If victim is not -breathing, give artificial
respiration; if breathing is difficult, give oxygen. Remove and isolate
contaminated clothing at site. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Keep victim quiet and maintain normal body temperature. Keep victim under
observation since effects may be delayed (DOT 1984, Guide 28).
COMMENTS
Sources searched but no information found:
DASE 1980
Weiss 1980
Clayton and Clayton 1981-82
Oilman 1985
Gosselin 1981
OSHA 1984
Hayes 1982
Student 1981
Doull 1980
NIOSH/OSHA 1978
-------
CAS Registry Number: 13494-80-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TELLURIUM
CAS Registry Number: 13494-80-9
Synonyms: Aurum Paradoxum; Metallum Problematum
Chemical Formula: Te
Molecular Weight: 127.60
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: 1814°F, 989.9°C (amorphous powder) (*Merck 1976); 2534°F,
1390°C (crystalline solid) (Weast 1984, p. B-146)
Specific Gravity (H2O=1): 6.24 (Weiss 1980, p. 1158)
Vapor Pressure (mmHg): 1 at 520°C (Sax 1984, p. 2501)
Melting Point: 842°F, 449.8°C (*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Merck 1983, p. 8970)
Appearance and Odor: Grayish-white, lustrous, brittle, crystalline solid;
dark-gray to brown, amorphous powder with metal characteristics (*Merck
1976).
-------
CAS Registry Number: 13494-80-9
Page 2 of 3
TELLURIUM
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 0.1 mg/ms (NIOSH/OSHA 1978, p. 172-173)
ACGIH TLV: TWA 0.1 mg/m3 (*ACGIH 1980)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (NIOSH/OSHA 1978, p. 172-173)
Skin: Yes (NIOSH/OSHA 1978, p. 172-173)
Ingestion: Yes (NIOSH/OSHA 1978, p. 172-173)
Health Hazards (Acute, Delayed, and Chronic): Causes central nervous
system depression (Merck 1983, p. 1307). Moderate skin and eye irritant
(Weiss 1980, p. 1158). Tellurium is capable of doing harm within the body
by replacing the essential element sulfur (Arena 1979, p. 269).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Use water spray (Weiss 1980, p. 1158). Tellurium
will burn only slowly in air (Clayton and Clayton 1981-82, p. 2137).
Special Fire Fighting Procedures: Straight water streams will scatter
molten tellurium oxide. Wear goggles, rubber gloves, and proper respirator
with filter (Weiss 1980, p. 1158).
Unusual Fire and Explosion Hazards: A finely divided suspension of
elemental tellurium in air will explode (*NFPA 1978). Burning tellurium
produces toxic tellurium oxide gas (Weiss 1980, p. 1158).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Encyc Occupat Health and Safety 1971)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Solid sodium (*NFPA 1978);
halogens, interhalogens, metals, hexalithium disilicide (Sax 1984, p.
2501). Reacts with nitric acid; reacts with concentrated sulfuric acid
forming a red solution. Dissolves in potassium hydroxide in the presence
of air with formation of deep red solution; combines with halogens (Merck
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CAS Registry Number: 13494-80-9
Page 3 of 3
TELLURIUM
SECTION V (continued)
1983, p. 1307). Antimony and chlorine trifluoride; chlorine trifluoride
reacts vigorously with tellurium producing flame. Fluorine and tellurium
react with incandescence. Lithium silicide attacks tellurium with
incandescence. Reaction with zinc is accompanied by incandescence (same
potential with cadmium, only hazard is less). A vigorous reaction results
when liquid tellurium is poured over solid sodium (*NFPA 1978).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of tellurium oxide (Sax 1984, p. 2501).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Coloring agent in chinaware, porcelains, enamels, glass; producing black
finish on silverware; semiconductor devices and research; manufacturing
special alloys of marked electrical resistance (*Merck 1976). Improves
mechanical properties of lead; powerful carbide stabilizer in cast iron
(*Encyc Occupat Health and Safety 1971); tellurium vapor in "daylight"
lamps, vulcanization of rubber (*Clayton and Clayton 1981-82). Blasting
caps (*Weast 1979). Semiconductor research (Merck 1983, p. 1307).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill or leak; collect spilled material in the most
convenient and safe manner and deposit in sealed containers for reclamation
or for disposal in a secured sanitary landfill. Liquids containing
tellurium should be absorbed in vermiculite, dry sand, earth or a similar
material (*NIOSH/OSHA 1981).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 13494-80-9
Page 1 of 3
Emergency First Aid Treatment Guide
for
TELLURIUM
(13494-80-9.)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Silvery or grayish-white lustrous solid, dark gray to brown
amorphous powder.
Commercial Forms - Powder, sticks, slabs, and tablets.
Uses - Coloring agent in chinaware, porcelains, enamels, glass, black finish on
silver, semiconductors, manufacturing special alloys of marked electrical
resistance, carbide stabilizer in cast iron, lamps, vulcanization of rubber,
blasting caps, catalyst.
Materials to Avoid - Acids.
Caution: When heated to decomposition, toxic fumes of tellurium oxide will be
emitted. Avoid sources of extreme heat.
Other Names - Aurum paradoxum, metallum pioblematum.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate.
Signs and Symptoms of Acute Tellurium Exposure:
Signs and symptoms of acute exposure to tellurium may include drowsiness,
malaise, lassitude, weakness, and dizziness. Gastrointestinal symptoms may
include nausea, vomiting, anorexia, and constipation.
-------
EFATG
CAS Registry Number: 13494-80-9
Page 2 of 3
TELLURIUM
A metallic taste, garlicky breath, and profuse sweating may be noted. Kidney
damage, liver injury, and pulmonary effects may also occur. Dermal exposure
may result in dermatitis (red, inflamed skin).
Emergency Life-Support Procedures:
Acute exposure to tellurium may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to tellurium.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to tellurium.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
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EFATG
CAS Registry Number: 13494-80-9
Page 3 of 3
TELLURIUM
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of tellurium is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities 01
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 14167-18-1
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- SALCOMINE
CAS Registry Number: 14167-18-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 950) Cobalt,
N,N'-Ethylenebis(Salicylideneiminato)-; bis(Salicylaldehyde)Ethylenediimine
Cobalt(II); Cobalt, ((2,2'-(l,2-Ethanediylbis(Nitrilomethylidyne))bis
(Phenolato))(2-)-N,N',O,O')-; Cobalt, ((alpha,alpha'-(Ethylenedinitrilo)
Di-o-Cresolato)(2-))-; N,N'-Ethylenebis(Salicylideneiminato)Cobalt(II);
Salcomin; Salcomine Powder
Chemical Formula: C16H14CoN2O2
Molecular Weight: 325.25
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(mouse) 0.39 mg/liter (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Cobalt Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=I): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 14167-18-1
Page 2 of 3
SALCOMINE
SECTION II (continued)
Appearance and Odor: Not Found
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 14167-18-1
Page 3 of 3
SALCOMINE
SECTION VI - USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Weast 1979
Sax 1984
Hawley 1981
Hayes 1982
Gosselin 1984
Clayton and Clayton 1981-82
DOT 1984
Merck 1983
Physicians' Desk Reference 1985
Oilman 1985
Verschueren 1983
Farm Chemicals Handbook 1984
Encyc Occupat Health and Safety 1983
Doull 1980
Weiss 1980
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CAS Registry Number: 15271-41-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - BICYCLO[2.2.1]HEPTANE-2-CARBONITRILE,
5-CHLORO-6-((((METHYLAMINO)CARBONYL)OXY)IMINO)-,(lS-(l ALPHA,
2 BETA, 4 ALPHA, 5 ALPHA, 6E))-
CAS Registry Number: 15271-41-7
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 865) 2-Norbornanone,
endo-3-Chloro-exo-6-Cyano-, O-(Methylcarbamoyl)Oxime;
endo-3-Chloro-exo-6-Cyano-2-Norbornanone O-(Methylcarbamoyl)Oxime;
2-exo-Chloro-6-endo-Cyano-2-Norbornanone-O-(Methylcarbamoyl)Oxime;
3-Chloro-6-Cyano-2-Norbornanone-O-(Methylcarbamoyl)Oxime; 3-Chloro-6-
Cyanonorbornanone-2 Oxime O,N-Methylcarbamate; 5-Chloro-6-((((Methylamino)
Carbonyl)Oxy)Imino)Bicyclo[2.2.1]Heptane-2-Carbonitrile; exo-5-Chloro-6-
Oxo-endo-2-Norbornanecarbonitrile O-(Methylcarbamoyl)Oxime;
Compound UC-20047 A; ENT 25,962; Tranid; UC 20047; UC 20,047A
Chemical Formula: C10H12C1N3O2
Molecular Weight: 241.70
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Va ue Used for Listing Under Section 302: LD50 oral (rat)
19 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 318-320°F, 159-160°C (Merck 1983, p. 1369)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 15271-41-7
Page 2 of 4
BICYCLOI2.2.1JHEPTANE-2-CARBONITRILE...
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Yes (Sax 1984, p. 692)
Ingestion: Yes (Sax 1984, p. 692)
Health Hazards (Acute, Delayed, and Chronic): High oral and dermal
toxicity (Sax 1984, p. 692). Carbamates are cholinesterase inhibitors
(Gosselin 1984, p. 111-86).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: A carbamate insecticide (Buchel 1983, p. 127).
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: A carbamate insecticide (Buchel 1983,
p. 127). Move container from fire area if you can do so without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material. Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Wear positive pressure
breathing apparatus and special protective clothing. Remove and isolate
contaminated clothing at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of chlorine containing compounds and nitrogen oxides
(Sax 1984, p. 692).
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CAS Registry Number: 15271-41-7
Page 3 of 4
BICYCLO[2.2.1JHEPTANE-2-CARBONITRILE...
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of chlorine containing compounds and nitrogen oxides
(Sax 1984, p. 692).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Acaricide used experimentally for residual control of mobile forms of
spider mites, including several phosphate resistant strains. It is neither
ovicidal nor systemic and has not been registered (Farm Chemicals Handbook
1984, p. C229).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
•
A carbamate insecticide (Buchel 1983, p. 127). Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 15271-41-7
Page 4 of 4
BICYCLO[2.2.1]HEPTANE-2-CARBONITRILE.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms of carbamate poisoning are
similar to those of parathion poisoning and may include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, dizziness,
giddiness, weakness, muscle twitching, difficult breathing, sensation of
tightness of chest, blurring or dimness of vision, and loss of muscle
coordination. Death may occur from failure of the respiratory center,
paralysis of the respiratory muscles, intense bronchoconstriction, or all
three (Gosselin 1984, pp. IH-88, 89).
Emergency and First Aid Procedures: An insecticidal carbamate (Buchel
1983, p. 127). Move victim to fresh air; call emergency medical care. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
- ^-contaminated clothing and shoes at the site.- Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Hayes 1982
Weast 1979
ACGIH 1983
NIOSH/OSHA 1978
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Clayton and Clayton 1981-82
Arena 1979
Encyc Occupat Health and Safety 1983
Doull 1980
Hawley 1981
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CAS Registry Number: 16752-77-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - METHOMYL
CAS Registry Number: 16752-77-5
Synonyms: Acetimidic Acid, Thio-N-((Methylcarbamoyl)oxy)-, Methyl Ester;
l-(Methylthio)Acetaldehyde O-Methylcarbamoyloxime; l-(Methylthio)
Ethylideneamino Methylcarbamate; 3-Thiabutan-2-one, O-(Methylcarbamoyl)Oxime;
Acetimidic Acid, N-((Methylcarbamoyl)Oxy)Thio-, Methyl Ester; Acetimidothioic
Acid, Methyl-, N-(Methylcarbamoyl) Ester; Du Pont Insecticide 1179; Du Pont
1179; Ethanimidothioic Acid, N-(((Methylamino)Carbonyl)Oxy)-, Methyl Ester; IN
1179; Insecticide 1,179; Lannate; Mesomile; Methyl N-((((Methylamino)Carbonyl)
Oxy)Ethanimido)Thioate; Methyl N-((Methylcarbamoyl)Oxy)Thioacetimidate; Methyl
N-[[(Methylamino)Carbonyl] OxyJEthanimidothioate; Methyl O-(Methylcarbamoyl)
Thiolacetohydroxamate; N-[(Methylcarbamoyl)Oxy]Thioacetimidic Acid Methyl
Ester; N-[[(Methylamino) Carbonyl]Oxy]Ethanimidothioic Acid Methyl Ester;
Nudrin; S-Methyl N-(Methylcarbamoyloxy)Thioacetimidate; SD 14999; WL 18236
Chemical Formula: C5H10N2O2S
Molecular Weight: 162.23
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(mouse) 10 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.2946 at '/5°F, 24°C (*Merck 1983)
Vapor Pressure (mmHg): 0.00005 at 77°F, 25°C (*ACGIH 1980)
Melting Point: 172-174°F, 78-79°C (*Merck 1983)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 16752-77-5
Page 2 of 3
METHOMYL
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 5.8 g/100 ml (Farm Chemicals Handbook 1984, p. C147)
Appearance and Odor: White crystalline solid with slight sulfurous smell
(*Farm Chemicals Handbook 1984)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: TWA 2.5 mg/ms (*ACGIH 1983)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Jones 1977)
Skin: Yes (*Jones 1977)
Ingestion: Yes (*Jones 1977)
Health Hazards (Acute, Delayed, and Chronic): Methomyl has high oral
toxicity, moderate inhalation toxicity and low skin toxicity (Sax 1984, p.
1874). The probable oral lethal dose for humans is between 7 drops and 1
teaspoon for a 150 pound adult. Death is due to respiratory arrest
(*Gosselin 1984).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamate Pesticide, Solid) Use
agent suitable for type of surrounding fire. Use water in flooding
quantities as a fog. Use alcohol foam, carbon dioxide, or dry chemical
(Student 1981, p. 104).
Special Fire Fighting Procedures: (Non-Specific -- Carbamate Pesticide,
Solid) Wear self-contained breathing apparatus (Student 1981, p. 104).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
1874).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 16752-77-5
Page 3 of 3
METHOMYL
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Worthing 1979)
Conditions to Avoid: Do not subject liquid formulations to
temperatures below 32°F (*Farm Chemicals Handbook 1984).
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p.
1874).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
A nematocide, and an insecticide on vegetables, tobacco, cotton, alfalfa,
soy beans, and corn (*SRI).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Carbamate Pesticide, Solid) Keep unnecessary people away;
isolate hazard areas and deny entry. Stay upwind and keep out of low
areas. Do not touch spilled material, or handle broken packages without
protective equipment. Do not breathe dust, vapors, or the fumes from
burning material (Student 1981, p. 104; DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 16752-77-5
Page 1 of 3
Emergency First Aid Treatment Guide
for
METHOMYL
(16752-77-5)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White, crystalline solid.
Odor - Slightly sulfurous.
Commercial Forms - Water-soluble liquid or powder.
Use - Insecticide.
Caution: Flammable. Avoid sources of extreme heat or ignition including
sparks or fire. Methomyl will liberate toxic nitrogen and sulfur oxide fumes
when heated to decomposition.
Other Names - Acetimidic acid, thio-N-((methylcarbamoyl)oxy)-, methyl ester;
Dupont 1179; Nudrin.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, diazepam, phenytoin, protopam.
Signs and Symptoms of Acute Methomyl Exposure:
Acute exposure to methomyl usually leads to a cholinergic crisis. Signs and
symptoms may include increased salivation, lacrimation (tearing), spontaneous
defecation, and spontaneous urination. Pinpoint pupils, blurred vision,
tremor, muscle twitching, and loss of muscle coordination may occur. Mental
confusion, convulsions, and coma may also be noted.
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CAS Registry Number: 16752-77-5
Page 2 of 3
METHOMYL
Gastrointestinal effects include nausea, vomiting, diarrhea, and abdominal
pain. Bradycardia (slow heart rate) occurs frequently. Dyspnea (shortness of
breath), pulmonary edema, and respiratory arrest may also occur.
Emergency Life-Support Procedures:
Acute exposure to methomyl may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to methomyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to methomyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
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CAS Registry Number: 16752-77-5
Page 3 of 3
METHOMYL
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of methomyl is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of methomyl may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); child* en 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 17702-41-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - DECABORANE(14)
CAS Registry Number: 17702-41-9
Synonyms: Boron Hydride (B10H14); Decaborane; Decaboron Tetradecahydride
Chemical Formula: B10H14
Molecular Weight: 122.22
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(mouse) 0.06 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTIC 5
Physical State: Solid
Boiling Point: 415°F, 213°C (*Weast 1979)
Specific Gravity (H2O=1): 0.95 at 25°C (*Weast 1979)
Vapor Pressure (mmHg): 19 at 100°C (*Sax 1975)
Melting Point: 211°F, 99.5°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble in cold water (*Weast 1979)
Appearance and Odor: White crystals (*Weast 1979) or colorless
crystalline needles (*NFPA 1978) with an intense, bitter, chocolate-like
odor (*Browning 1969)
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CAS Registry Number: 17702-41-9
Page 2 of 4
DECABORANE(14)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: 0.3 mg/m3 (0.05 ppm) (NIOSH/OSHA 1978, p. 76).
ACGIH TLV: TWA 0.3 mg/m3 (0.05 ppm); STEL 0.9 mg/m3 (0.15 ppm) (skin)
(ACGIH 1984, p. 17)
IDLH: 20 ppm (NIOSH/OSHA 1978, p. 76)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (NIOSH/OSHA 1978, p. 77)
Ingestion: Yes (NIOSH/OSHA 1978, p. 77)
Health Hazards (Acute, Delayed, and Chronic): May cause death or
permanent injury after very short exposure to small quantities (*Sax 1975).
- — •Produces-marked irritation-of skirrand mucous membranes (*Encyc Occupat
Health and Safety 1971). May cause liver injury (*Rumack 1975 to Present).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 176°F, 80°C (CC) (*NFPA 1978)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Small fires: cover with sand, earth or water
spray and keep it wet. Large fires: water spray or fog. Do not scatter
spilled material with more water than needed for fire control. Move
container from fire area if you can do so without risk. Spray cooling
water on containers that are exposed to flames until well after fire is
out. For massive fire in cargo area, use unmanned hose holder or monitor
nozzles; if this is impossible, withdraw from area and let fire burn (DOT
1984, Guide 38).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
positive pressure breathing apparatus and full protective clothing (DOT
1984, Guide 38).
Unusual Fire and Explosion Hazards: Decaborane mixed with carbon
tetrachloride is dangerously shock sensitive (*Merck 1976). It reacts
slowly with air but when mixed with air or oxygen, it becomes highly
flammable and may explode. It undergoes an explosive reaction with most
oxidizing agents including halogenated hydrocarbons (*Encyc Occupat Health
and Safety 1971).
NFPA Flammability Rating: 2
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CAS Registry Number: 17702-41-9
Page 3 of 4
DECABORANE(14)
SECTION V ~ REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Merck 1976)
Conditions to Avoid: Normally stable, but becomes unstable at
elevated temperature and pressure (*NFPA 1978).
Incompatibility (Materials to Avoid): Incompatible with ethers;
halocarbons; oxygen at 100°C; dimethyl sulfoxide (Sax 1984, p. 856); most
oxidizing agents, including halogenated hydrocarbons (*Encyc Occupat Health
and Safety 1971). It is corrosive to natural rubber, some synthetic
rubbers, some greases, and some lubricants (Weiss 1980, p. 301).
Hazardous Decomposition or Byproducts: It may give off toxic fumes of
unburned material (Weiss 1980, p. 301). When heated to decomposition, it
emits toxic fumes of boron oxides (Sax 1984, p. 856).
Hazardous Polymerization: May Occur: ^
May Not Occur: Yes (Weiss 1980, p. 301)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
In rocket propellants; as catalyst in olefin polymerization (*Merck 1976);
rubber vulcanizer (*Browning 1969); to coat metals with corrosion resistant
boron; in manufacture of plastics (Thienes 1972); oxygen scavenger;
mothproofing; dye-stripping; reducing and fluxing agent (*Clayton and
Clayton 1981-82); stabilizer and rayon delustrant (*Hawley 1977).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Ventilate area of spill. For small quantities, sweep into paper or other
suitable material, place in appropriate container and burn in safe place
(such as fume hood). Large quantities may be reclaimed. If reclamation is
not practical, dissolve in flammable solvent (such as alcohol) and atomize
in suitable combustion chamber equipped with appropriate effluent gas
cleaning device (*NIOSH/OSHA 1981). Only persons with adequate personal
protective equipment should be allowed in vicinity of containers.
(*Encyc Occupat Health and Safety 1971). Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: cover with water, sand or earth; shovel into metal container
and keep material under water. Large spills: dike for later disposal
and cover with wet sand or water. Clean up only under supervision of
an expert (DOT 1984, Guide 38).
SECTION VIII « PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
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CAS Registry Number: 17702-41-9
Page 4 of 4
DECABORANE(14)
SECTION VIII (continued)
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 17702-41-9
Page 1 of 4
Emergency First Aid Treatment Guide
for
DECABORANE
(17702-41-9)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Forms - White crystals or colorless crystalline needles.
Odor - Intense, bitter, chocolatelike.
Commercial Form - 95% pure solid.
Uses - Rocket propellant, catalyst in olefin polymerization, rubber vulcanizer,
manufacture of plastics, oxygen scavenger, mothproofing, metal coating, dye-
stripping, reducing and fluxing agent, stabilizer and rayon delustrant.
Materials to Avoid - Oxidizers, halogenated hydrocarbons, natural and synthetic
rubber, grease, lubricants, acetone.
Caution: Flammable solid; unstable at elevated temperature. Avoid sources of
heat including fire. Decaborane will liberate toxic boron oxide fumes when
heated to decomposition.
Other Names - Boron hydride, decaboron tetradecahydride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbital.
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EFATG
CAS Registry Number: 17702-41-9
Page 2 of 4
DECABORANE
Signs and Symptoms of Acute Decaborane Exposure:
Warning: Effects may be delayed up to 24 hours. Caution is advised.
Signs and symptoms of acute exposure to decaborane may include tightness in the
chest, dyspnea (shortness of breath), cough, and wheezing. Nausea and
pulmonary edema may also occur. Neurological effects of acute exposure include
dizziness, headache, weakness, incoordination, muscle spasms, tremor, and
seizures. Exposure to decaborane may irritate or burn the skin, eyes, and
mucous membranes.
Emergency Life-Support Procedures:
-Acute exposure to decaborane may require- decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to decaborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
. for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to decaborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
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EFATG
CAS Registry Number: 17702-41-9
Page 3 of 4
DECABORANE
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas at least twice with large amounts of cool water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of decaborane is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of decaborane may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
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EFATG
CAS Registry Number: 17702-41-9
Page 4 of 4
DECABORANE
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
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CAS Registry Number: 17702-57-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - FORMPARANATE
CAS Registry Number: 17702-57-7
Synonyms: (NIOSH/RTECS Synonyms 1983, Volume 1, p. 834): Carbamic Acid,
Methyl-, 4-(((Dimethylamino)Methylene)Amino)-m-Tolyl Ester; ENT 27,305;
UC-25074; Union Carbide UC-25074
Chemical Formula: C12H17N3O2
Molecular Weight: 235.32
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7.2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes c: No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
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CAS Registry Number: 17702-57-7
Page 2 of 3
FORMPARANATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: No: Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
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CAS Registry Number: 17702-57-7
Page 3 of 3
FORMPARANATE
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
Buchel 1983
Clayton and Clayton 1981-82
Farm Chemicals Handbook 1984
Hawley 1981
Hayes 1982
Merck 1983
Sax 1984
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CAS Registry Number: 19287-45-7
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- DIBORANE
CAS Registry Number: 19287-45-7
Synonyms: Boroethane; Boron Hydride; Diborane; Diboron Hexahydride
Chemical Formula: B2H6
Molecular Weight: 27.69
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC60 inhalation
(mouse) 0.033 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Gas
Boiling Point: -135°F, -92.5°C (*Merck 1983)
Specific Gravity (H2O=1): 0.210 at 15°C (*Merck 1983)
Vapor Pressure (mmHg): 224 at -112°C (*Sax 1979)
Melting Point: -265°F, -165°C (*Merck 1983)
Vapor Density (AIR=1): 1.0 (NFPA 1984, p. 325M-32)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless gas with a repulsive, sickly-sweet odor
(*Merck 1983)
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CAS Registry Number: 19287-45-7
Page 2 of 3
DIBORANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: 0.1 mg/m3 (0.1 ppm) (NIOSH 1987, p. 94)
ACGIH TLV: TWA 0.1 mg/ms (0.1 ppm) (ACGIH 1986-87, p. 15)
IDLH: 40 ppm (NIOSH/OSHA 1978, p. 78)
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (*Encyc Occupat Health and
Safety 1983)
Skin: Yes (*Encyc Occupat Health and Safety 1983)
Ingestion: Yes (*Encyc Occupat Health and
Safety 1983)
Health Hazards (Acute, Delayed, and Chronic): "Boranes are highly toxic by
inhalation, skin absorption or ingestion. They may produce acute or
chronic poisoning (*Encyc Occupat Health and Safety 1983). Diborane is an
irritant to the lungs and kidneys (Doull 1980, p. 441). The primary effect
of diborane poisoning is lung congestion caused by local tissue irritation
produced by the exothermic reaction of hydrolysis (Clayton and Clayton
1981-82, p. 2991).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): -130°F, -90°C (*Hawley 1978)
Flammable Limits:
LEL: 0.8% (*NFPA 1978)
UEL: 88% (*NFPA 1978)
Extinguishing Methods: Inert gas substances such as liquid nitrogen are
recommended (*Encyc Occupat Health and Safety 1983).
Special Fire Fighting Procedures: Firefighting should be done from an
explosion-resistant location. Use water from unmanned monitors or hose
holders to keep fire-exposed containers cool. If it is necessary to stop
flow of gas, use water spray to protect personnel effecting shut-off.
Personnel should be evacuated immediately. Self-contained breathing
apparatus and full protective clothing should be worn (*NFPA 1978).
Isolate for 1/2 mile in all directions if tank car or truck is involved in
fire (DOT 1984, Guide 18).
Unusual Fire and Explosion Hazards: It will ignite spontaneously in moist
air at room temperature. Also, it reacts violently with vaporizing
liquid-type extinguishing agents (NFPA 1984, p. 49-36).
NFPA Flammability Rating: 4
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CAS Registry Number: 19287-45-7
Page 3 of 3
DIBORANE
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (NFPA 1984, p. 49-36).
Stable:
Conditions to Avoid: Avoid moist air, electrical sparks, open flames
or any other heat source (NFPA 1984, p. 49-36).
Incompatibility (Materials to Avoid): Incompatible with air, halogenated
compounds, aluminum, lithium, active metals, oxidized surfaces (NIOSH/OSHA
1978, p. 78), chlorine, fuming nitric acid, nitrogen trifluoride, oxygen,
and phosphorus trifluoride (*NFPA 1978).
Hazardous Decomposition or Byproducts: It hydrolyzes in water to hydrogen
and boric acid (*Merck 1983).
Hazardous Polymerization: May Occur: Yes (*Thienes 1972)
May Not Occur:
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
It is an intermediate for trialkyl and triaryl boranes (polymerization
catalyst); copolymerization catalyst for styrene and butadiene;
polymerization catalyst for olefins and epoxides. It is also used in the
production of hard boron coatings on metals and ceramics; rocket
propellants; as a rubber vulcanizer; reducing agent; flame-speed
accelerator and a doping gas (*SRI, *Merck 1983).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind. Shut off ignition sources; no flares, smoking or flames in
hazard area. Stop leak if possible. Use water spray to reduce vapors.
Evacuate area endangered by gas. Isolate for 1/2 mile in all directions if
tank car or truck is involved in fire (DOT 1984, Guide 18).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 19287-45-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
DIBORANE
(19287-45-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless gas.
Odor - Repulsive, sickly sweet.
Commercial Form - 95 to 99% pure compressed gas in steel cylinders.
Uses - Chemical intermediate, catalyst, reducing agent, rubber vulcanizer,
doping agent, rocket propellant, flame speed accelerator.
Materials to Avoid - Oxidizers, aluminum, halogenated compounds, water (except
for emergency life support).
Caution: Explosion potential is high. Avoid sources of extreme heat or
ignition including sparks or fire.
Other Names Boroethane, boron hydride, diboron hexahydride.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Diborane Exposure:
Warning: Effects may be delayed up to 24 hours. Caution is advised.
-------
EFATG
CAS Registry Number: 19287-45-7
Page 2 of 3
DIBORANE
Signs and symptoms of acute exposure to diborane may include tightness in the
chest, dyspnea (shortness of breath), cough, and wheezing. Nausea and
pulmonary edema may also occur.
Other possible effects of acute exposure include dizziness, headache, weakness,
lack of coordination, muscle spasms, tremor, and seizures. Exposure to
diborane may irritate or burn the skin, eyes, and mucous membranes.
Emergency Life-Support Procedures:
Acute exposure to diborane may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to diborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. - Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to diborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
-------
EFATG
CAS Registry Number: 19287-45-7
Page 3 of 3
DIBORANE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas at least twice with large amounts of cool water.
•6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
-------
CAS Registry Number: 19624-22-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PENTABORANE
CAS Registry Number: 19624-22-7
Synonyms: Pentaborane (9); Pentaboron Nonahydride; (9)-Pentaboron Nonahydride
Chemical Formula: B5H9
Molecular Weight: 63.17
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.018 mg/liter 4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 140°F, 60°C (*Merck 1976)
Specific Gravity (H2O=1): 0.61 at 0°C/4°C (Merck 1983, p. 1020)
Vapor Pressure (mmHg): 171 at 20°C (NIOSH 1985, p. 184)
Melting Point: -51.9°F, -46.6°C (Merck 1983, p. 1020)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Colorless liquid with a strong, pungent, foul, sour
milkish odor (*CHRIS 1978).
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CAS Registry Number: 19624-22-7
Page 2 of 4
PENTABORANE
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: TWA 0.01 mg/m3 (0.005 ppm) (NIOSH/OSHA 1978, p. 148)
ACGIH TLV: TWA 0.01 mg/ms (0.005 ppm); STEL 0.03 mg/ms (0.015 ppm) (*ACGIH
1980)
IDLH: 3 ppm (NIOSH/OSHA 1978, p. 148)
Other Limits Recommended: Short-term inhalation limits: 25 ppm for 5
minutes, 8 ppm for 15 minutes, 4 ppm for 30 minutes; 2 ppm for 60 minutes
(Weiss 1980, p. 731).
Routes of Entry: Inhalation: Yes (Sax 1984, p. 2124)
Skin: Not Found
Ingestion: No (Weiss 1980, p. 731)
Health Hazards (Acute, Delayed, and Chronic): May cause death or
permanent injury after very short exposure to small quantities (Sax 1984,
p. 2124).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 86°F, 30°C (CC) (Hawley 1981, p. 782)
Flammable Limits:
LEL: 0.42% (NIOSH/OSHA 1978, p. 148)
UEL: 98% (Weiss 1980, p. 731)
Extinguishing Methods: If material is on fire or involved in fire, do not
extinguish unless flow can be stopped. Do not use water. Extinguish small
fires with dry chemical or carbon dioxide (Student 1981, p. 394). For
large fires withdraw and let burn (DOT 1984, Guide 75).
Special Fire Fighting Procedures: Move container from fire area if you
can do it without risk. Cool containers that are exposed to flames with
water from the side until well after fire is out. For massive fire in
cargo area, use unmanned hose holder or monitor nozzles; if this is
impossible, withdraw from area and let fire burn. Wear positive pressure
breathing apparatus and full protective clothing (DOT 1984, Guide 75).
Evacuation: if fire becomes uncontrollable or container is exposed to
direct flame -- evacuate for a radius of 1,500 feet. If material is
leaking (not on fire), downwind evacuation must be considered (Student
1981, p. 394).
Unusual Fire and Explosion Hazards: Ignites spontaneously in air (Weiss
1980, p. 731). Reacts violently with halogenated extinguishing agents
(*NFPA 1978). Boron hydrides present considerable fire and explosion
hazard. They undergo explosive reaction with most oxidizing agents,
including halogenated hydrocarbons (*Encyc Occupat Health and Safety 1971).
Fires tend to reignite (Weiss 1980, p. 731).
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CAS Registry Number: 19624-22-7
Page 3 of 4
PENTABORANE
SECTION IV (continued)
NFPA Flammability Rating: 3
SECTION V - REACTIVITY DATA
Stability: Unstable: Yes (Merck 1983, p. 1020)
Stable:
Conditions to Avoid: Direct sunlight and sources of ignition (*Encyc
Occupat Health and Safety 1983); decomposes very slowly at 150C (Merck
1983, p. 1020).
Incompatibility (Materials to Avoid): Dimethyl sulfoxide (Sax 1984, p.
2124), water, most oxidizing agents (including halogenated hydrocarbons)
(*Encyc Occupat Health and Safety 1971 and see Section IV).
Hazardous Decomposition or Byproducts: On decomposition, it emits toxic
fumes and can react vigorously with oxidizing materials (Sax 1984, p.
2124).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 731)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Fuel for air-breathing engines; propellant (*Hawley 1977).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material, stop leak if you can do it without risk.
For spills dike for later disposal and do not apply water unless directed
to do so. Clean up only under supervision of an expert. Keep unnecessary
people away; isolate hazard area and deny entry. Stay upwind; keep out of
low areas. Ventilate closed spaces before entering them (DOT 1984, Guide
75). Avoid breathing vapors, and keep upwind. Avoid bodily contact with
the material. Do not handle broken packages without protective equipment.
Wash away any material which may have contacted the body with copious
amounts of water or soap and water (Student 1981, p. 394).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 19624-22-7
Page 4 of 4
PENTABORANE
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Death can occur by central nervous system
poisoning. Inhalation of low concentrations causes behavioral changes,
loss of recent memory, poor judgment, nausea, vomiting, drowsiness, and
difficulty in focusing. Upon inhalation of higher concentrations,
headache, dizziness, nervous excitation, muscular pain, uncoordination,
cramps, tremors, convulsions, and coma may occur (*Grant 1974; *Thienes
1972; *Encyc Occupat Health and Safety 1983; *Casarett 1975; *ACGIH 1980).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Remove and isolate contaminated clothing and shoes at the site. Keep
victim quiet and maintain normal body temperature (DOT 1984, Guide 75).
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CAS Registry Number: 20830-75-5
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ DIGOXIN
CAS Registry Number: 20830-75-5
Synonyms: Acygoxin; Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-
hexopyranosyl-(hexopyranosyl-(l-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-
12,14-dihydroxy-,; Chloroformic digitalin; Lanacordin; Lanatilin; Lanicor;
Lanoxin; Rougoxin; Saroxin; Vanoxin; Cordioxil; Davoxin; Digacin; Digitalis
Glycoside; Dilanacin; Dixina; Homolle's Digitalin
Chemical Formula: C41H64O14
Molecular Weight: 780.92
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (cat)
0.2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposition range 446-509°F, 230-265°C (Merck 1983, p.
460)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (*Sunshine 1969)
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CAS Registry Number: 20830-75-5
Page 2 of 3
DIGOXIN
SECTION II (continued)
Appearance and Odor: Clear to white crystals or white crystalline powder.
Odorless (*Osol 1975).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
••--•«• "Ingestion: Yes (*Gosselin 1976)
Health Hazards (Acute, Delayed, and Chronic): Material is a digitalis
glycoside. Ingestion can cause death. Material is considered super toxic;
probable human oral lethal dose is less than 5 mg/kg, a taste (less than 7
drops) for a 70 kg (150 Ib.) person (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Persons at risk
include those taking drugs for thyroid and renal diseases (*Osol 1975,
*AHFS 1984). Quinidine and diuretics taken concurrently with digoxin can
be hazardous (Oilman 1985, p. 743). It should be used with extreme care
during pregnancy and in nursing mothers (*AHFS 1984).
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Medicines, Solid, Poison B)
Extinguish fire using agent suitable for type of surrounding fire; material
burns with difficulty. Use water in flooding quantities as fog.
Use alcohol foam, carbon dioxide, or dry chemical (Student 1981, p. 322).
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
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CAS Registry Number: 20830-75-5
Page 3 of 3
DIGOXIN
SECTION V (continued)
Conditions to Avoid: Avoid light (*AHFS 1984)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Material is a cardiotonic drug (*Goodman 1975).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Medicines, Solid, Poison B) Avoid breathing dusts, and
fumes from burning materials. Keep upwind. Avoid bodily contact with the
material. Wash away any material which may have contacted the body with
copious amounts of water or soap and water (Student 1981, p. 322).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece b^lf-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Data here refer specifically to
digitalis. Nausea and vomiting, headache, fatigue, weakness, drowsiness,
and abdominal discomfort are symptomatic of toxicity. Visual disturbances
(including blurring, halos, and aberrations of color), emotional disorders
(including confusion, disorientation, aphasia, delirium, and
hallucinations) and convulsions (*Gosselin 1976).
Emergency and First Aid Procedures: Not Found
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CAS Registry Number: 20859-73-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ALUMINUM PHOSPHIDE
CAS Registry Number: 20859-73-8
Synonyms: AIP; Al-Phos; Aluminum Phosphide (AP); Aluminum Monophosphide;
Celphos; Delicia; Delicia Gastoxin; Delia; Delia Gas EX-B; Detia-EX-B;
Phostoxin; Phostoxin-A; Quickphos
Chemical Formula: AIP
Molecular Weight: 57.95
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(human) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 2.85 at 15°C/4°C (*Merck 1976)
Vapor Pressure (mmHg): Not Found
Melting Point: Does not melt or decompose at temperatures up to 1000°C
(*Merck 1976)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found (also see Section V)
Appearance and Odor: Aluminum phosphide exists as dark gray or dark
yellow crystals (*Merck 1976)
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CAS Registry Number: 20859-73-8
Page 2 of 4
ALUMINUM PHOSPHIDE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 178)
Skin: Not Found
Ingestion: Yes (Gosselin 1984, p. 11-120)
Health Hazards (Acute, Delayed, and Chronic): Acute toxicity occurs
primarily by the inhalation route when aluminum phosphide decomposes into
the toxic gas, phosphine (*Rumack 1975 to Present). The human median
lethal dose for aluminum phosphide has been reported to be 20 mg/kg
(*NIOSH/RTECS 1985). Rated as super toxic: probable oral lethal dose is
less than 5 mg/kg or less than 7 drops for a 70 kg (150 Ib.) person
(Gosselin 1984, pp. II-119-120).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Do not use water or foam. Small fires can be
extinguished with dry chemical, soda ash, or lime. Large fires -- withdraw
from area and let fire burn. Move container from fire only if you can do
it without risk (DOT 1984, Guide 41).
Special Fire Fighting Procedures: Wear self-contained breathing apparatus
when fighting fires involving this material. If contact with the material
is anticipated, wear full protective clothing (Student 1981, p. 21).
Unusual Fire and Explosion Hazards: Releases toxic fumes on exposure to
moist air, water, or acids (*Merck 1976, *Peer Review Committee;
*Bretherick 1975).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Stable when dry (*Worthing 1979)
Conditions to Avoid: Moist air (*Merck 1976)
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CAS Registry Number: 20859-73-8
Page 3 of 4
ALUMINUM PHOSPHIDE
SECTION V (continued)
Incompatibility (Materials to Avoid): Water (*Peer Review Committee),
dilute mineral acids, dilute or concentrated hydrochloric acid (*Bretherick
1979).
Hazardous Decomposition or Byproducts: Phosphine gas (*Peer Review
Committee; *Bretherick 1979).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Insecticidal fumigant for grain, peanuts, processed food, animal feed, leaf
tobacco, cottonseed, and as space fumigant for flour mills, warehouses, and
railcars (Farm Chemicals Handbook 1984, p. C12); used in semiconductor
research (*Merck 1976).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Shut off ignition; no flares, smoking, or flames in hazard area. Do not
touch spilled material. Do not get water on spilled material or inside
container. Dike spill for later disposal. Shovel small spill into clean,
dry container, and cover. Move containers from spill area. Avoid
breathing dusts (Student 1981, p. 21). Cover large powder spill
with plastic sheet or tarp to minimize spreading. Clean up only under
supervision of an expert (DOT 1984, Guide 41).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
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CAS Registry Number: 20859-73-8
Page 4 of 4
ALUMINUM PHOSPHIDE
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
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EFATG
CAS Registry Number: 20859-73-8
Page 1 of 3
Emergency First Aid Treatment Guide
for
ALUMINUM PHOSPHIDE
(20859-73-8)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Dark gray or dark yellow crystals.
Commercial Forms - Tablets or pellets.
Uses - Fumigant, pesticide, semiconductor research.
Materials to Avoid - Acids, water (except for use in emergency life support).
Caution: Flammable. Avoid sources of heat or ignition including sparks or
fire. Toxic phosphine gas will be released upon contact with moisture.
Aluminum phosphide may spontaneously ignite in air.
Other Names - Al-Phos, Celphide, Celphine, Celphos, Delicia, Delia, Phostoxin,
Quickphos.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, normal saline, D5W,
Ringer's lactate, diazepam, phenytoin.
Signs and Symptoms of Acute Aluminum Phosphide Exposure:
Warning: Effects may be delayed for several hours. Caution is advised.
Acute exposure to aluminum phosphide usually results in headache, cough,
tightness and pain in the chest, shortness of breath, dizziness, lethargy, and
stupor. Muscle pain, fatigue, chills, tremor, lack of coordination, seizures,
and coma may be observed. Pulmonary edema and cardiac irregularities are also
commonly found.
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EFATG
CAS Registry Number: 20859-73-8
Page 2 of 3
ALUMINUM PHOSPHIDE
Gastrointestinal effects include nausea, vomiting, abdominal pain, and
diarrhea. Renal (kidney) damage, hepatic (liver) damage, and jaundice may also
occur. Contact with aluminum phosphide may cause severe burns to skin and
eyes.
Emergency Life-Support Procedures:
Acute exposure to aluminum phosphide may require decontamination and life
support for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to aluminum phosphide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to aluminum phosphide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas twice with soap and water.
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EFATG
CAS Registry Number: 20859-73-8
Page 3 of 3
ALUMINUM PHOSPHIDE
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
Ingestion Exposure: No information is available.
-------
CAS Registry Number: 21548-32-3
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ FOSTHIETAN
CAS Registry Number: 21548-32-3
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, page 510) Imidocarbonic
Acid, Phosphonodithio-, Cyclic Methylene P,P-Diethyl Ester; AC 64475; Acconem;
CL 64475; (Diethoxyphosphinylimino)-l,3-Dithietane; Geofos; Nem-a-tak;
Phosphoramidic Acid, 1,3 Dithietan-2-ylidene-, Diethyl Ester;
l,3-Dithietan-2-ylidenephosphoramidic Acid Diethyl Ester; Phosphonodithioimi-
docarbonic Acid Cyclic Methylene P,P-Diethylester (Merck 1983 Synonyms, p. 607)
2-(Diethoxyphosphinylimino)-l,3-Dithietane
Chemical Formula: C6H12NO3PS2
Molecular Weight: 241.28
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDSO oral (rat)
4.7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.3 at 25°C (Merck 1983, p. 607)
Vapor Pressure (mmHg): 0.0000065 at 25°C (Merck 1983, p. 607)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 21548-32-3
Page 2 of 4
FOSTHIETAN
SECTION II (continued)
Solubility in Water: 50 g/kg at 25°C (Merck 1983, p. 607)
Appearance and Odor: Pale yellow liquid, mercaptan-like odor (Merck 1983,
p. 607)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organic Phosphorus
Insecticides) (Hayes 1982, p. 301)
Skin: Yes (Sax 1984, p. 980)
Ingestion: Yes (Sax 1984, p. 980)
Health Hazards (Acute, Delayed, and Chronic): This compound is a liquid
organophosphorus insecticide (Buchel 1983, p. 86) Organic phosphorus
insecticides are absorbed by the skin, as well as by the respiratory and
gastrointestinal tracts (Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a liquid organophosphorus
insecticide (Buchel 1983, p. 86) This material may burn, but does not
ignite readily. For small fires, use dry chemical, carbon dioxide, water
spray, or foam. For large fires, use water spray, fog, or foam (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: This compound is a liquid
organophosphorus insecticide (Buchel 1983, p. 86) Stay upwind; keep out of
low areas. Move containers from fire area if you can do so without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material. Wear positive pressure breathing
apparatus and special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur
-------
CAS Registry Number: 21548-32-3
Page 3 of 4
FOSTHIETAN
SECTION IV (continued)
oxides (Sax 1984, p. 980). This compound is a liquid organophosphorus
insecticide (Buchel 1983, p. 86) Container may explode in heat of fire
(DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur
oxides (Sax 1984, p. 980).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a nematocide and insecticide (Merck 1983, p. 607).
Not registered as a pesticide in the U.S. (USEPA/Pe^ticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is a liquid organophosphorus insecticide (Buchel 1983, p. 86)
Stay upwind; keep out of low areas. Ventilate closed spaces before
entering them. Do not touch spilled material; stop leak if you can
do so without risk. Use water spray to reduce vapors. Small spills:
absorb with sand or other non-combustible absorbent material and place into
containers for later disposal. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
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CAS Registry Number: 21548-32-3
Page 4 of 4
FOSTHIETAN
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
"'"Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: This compound is a liquid
organophosphorus insecticide (BucheTI983, p'.'86) Move victim to fresh
air; call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
be delayed; keep victim under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 19 8
Hawley 1981
Weast 1979
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 21609-90-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- LEPTOPHOS
CAS Registry Number: 21609-90-5
Synonyms: Phosphonothioic Acid, Phenyl-, O-(4-Bromo-2,5-Dichlorophenyl)
O-Methyl Ester; Abar (Velsicol); Fosvel; K62-105; Lepton; MBCP; NK 711;
O-(2,5-Dichloro-4-Bromophenyl) O-Methyl Phenylthiophosphonate; O-(2,5-
Dichloro-4-Bromophenyl) O-Methyl Phenyl Thiophosphonate; O-(4-Bromo-2,5-
Dichlorophenyl) O-Methyl Phenylphosphonothioate; O-(4-Bromo-2,5-Dichloro-
phenyl) O-Methylphenylphosphonothioate; O-4-Bromo-2,5-Dichlorophenyl-O-Methyl
Phenylphosphonothioate; Oleophosvel; V.C.S.; VCS 5-D; VDS-506; Velsicol 506;
Velsicol VCS 506; VVS-506
Chemical Formula: C13H10BrCl2O2PS
Molecular Weight: 412.07
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 30 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.53 at 25°C (*Worthing 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: 158-159°F, 70.2-70.6°C (*Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 21609-90-5
Page 2 of 4
LEPTOPHOS
SECTION II (continued)
Solubility in Water: 2.4 mg/liter (*Worthing 1979)
Appearance and Odor: White crystalline (*Spencer 1982) or colorless
amorphous solid (*Worthing 1979); the technical product is a light tan
powder (*Spencer 1982).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Organophosphorus
Pesticide, n.o.s.) (DOT 1984, Guide 55)
Skin: Yes (*Sax 1979)
Ingestion: Yes (*Sax 1979)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic; it is capable of causing death or permanent injury by exposure
during normal use (*Sax 1979).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move container
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire. Fire may
produce irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 21609-90-5
Page 3 of 4
LEPTOPHOS
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1982)
Conditions to Avoid: Strong alkalies (*Worthing 1979)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Decomposes above 356°F, 180°C
(*Spencer 1982).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is used as an insecticide; its use is not permitted in the
U.S. (*SRI). Denied registration as a pesticide in the U.S. (USEPA/
Pesticide Index 1985).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Do not touch
spilled material; stop leak if you can do it without risk. Use water spray
to reduce vapors. Small dry spills: with clean shovel place material into
clean, dry container and cover; move containers from spill area (DOT 1984,
Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit.. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
-------
CAS Registry Number: 21609-90-5
Page 4 of 4
LEPT.OPHOS
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms may include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, headache, giddiness,
weakness, muscle twitching, difficult breathing, blurring or dimness of
vision, and loss of muscle coordination. Death may occur from failure of
the respiratory center, paralysis of the respiratory muscles, intense
bronchoconstriction, or all three (*Gosselin 1976).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Move victim to fresh air; call emergency medical care.
If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Speed in removing
material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 21908-53-2
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- MERCURIC OXIDE
CAS Registry Number: 21908-53-2
Synonyms: Mercury(II) Oxide; CI 77760; Hydrargyrum Oxid Flav; Mercuric Oxide,
Red; Mercuric Oxide, Solid (DOT); Mercuric Oxide, Yellow; Mercuric Oxides, Red
and Yellow; Mercury Monoxide; Mercury Oxide (HgO); Mercury(2+) Oxide; Natural
Montroydite; Red Oxide of Mercury; Red Precipitate; Santar; Santar M; Yellow
Mercuric Oxide; Yellow Oxide of Mercury; Yellow Precipitate
Chemical Formula: HgO
Molecular Weight: 216.61
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
18 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Mercury Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): 11.1 at 39°F, 4°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposes at 932°F, 500°C (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.053 grams/liter at 77°F, 25°C; 0.395 grams/liter
at 212°F, 100°C (*Weast 1979)
-------
CAS Registry Number: 21908-53-2
Page 2 of 4
MERCURIC OXIDE
SECTION II (continued)
Appearance and Odor: Red or orange-red heavy crystalline powder or
scales, yellow when finely powdered; odorless (*Merck 1976)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: (Mercury and inorganic compounds) Ceiling: 0.1 mg/m3 (NIOSH
1987, p. 152)
ACGIH TLV: (Mercury, aryl and inorganic compounds) TWA 0.1 mg/m3 (ACGIH
1986-87, p. 22)
IDLH: Not Found
Other Limits Recommended: NIOSH: 0.05 mg/m3, 10-hour TWA, as mercury
(NIOSH 1987, p. 152) IDLH: (Mercury and inorganic compounds) 28 mg/m3, as
mercury (NIOSH 1987, p. 152)
Routes of Entry: Inhalation: Yes (*Sax 1975)
Skin: Yes (*Sax 1975)
Ingestion: Yes (*Sax 1975)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by ingestion, inhalation, or skin absorption. Very short exposure to
small quantities may cause death or permanent injury (*Sax 1975).
Following ingestion, mercuric oxide is readily converted to mercuric
chloride, the most dangerous mercury compound. Mercuric oxide dust has a
corrosive effect on eyes, skin, and respiratory tract (*Rumack 1975 to
Present).
Medical Conditions Generally Aggravated by Exposure: People with a
history of allergies or known sensitization to mercury, chronic respiratory
disease, nervous system disorders, or kidney disorders are at increased
risk from exposure (*NIOSH/OSHA 1981).
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Not Flammable (Weiss 1980, p. 585)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (DOT
1984, Guide 53).
Special Fire Fighting Procedures: Wear full body protective clothing and
self-contained breathing apparatus (*Rumack 1975 to Present).
Unusual Fire and Explosion Hazards: When heated to decomposition (932°F,
500°C) it decomposes into mercury and oxygen. Fumes from fire may contain
-------
CAS Registry Number: 21908-53-2
Page 3 of 4
MERCURIC OXIDE
SECTION IV (continued)
poisonous mercury vapor; oxygen may increase intensity of fire (*CHRIS
1978). Explosion of mercuric oxide may occur with friction or application
of heat (*Rumack 1975 to Present).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Weiss 1980, p. 585)
Conditions to Avoid: Light; may decompose into mercury and oxygen
(*Merck 1976).
Incompatibility (Materials to Avoid): Reducing agents (*Merck 1976).
Hazardous Decomposition or Byproducts: Decomposes into mercury and oxygen
at 932°F, 500°C (*CHRIS 1978).
Hazardous Polymerization: May Occur:
May Not Occur: Yes (Weiss 1980, p. 585)
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Chemical intermediate for mercury salts, organic mercury compounds, and
chlorine monoxide; antisepti" in Pharmaceuticals; component of dry cell
batteries; pigment and glass modifier; fungicide; preservative in
cosmetics; analytical reagent; formerly used in antifouling paints (*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Isolate hazard area. Stay upwind; keep out of low areas. Do not touch
spilled material. Take up small spills with sand or other non-combustible
absorbent material and place into containers for later disposal. For small,
dry spills, use clean shovel to place material into clean dry containers.
Dike far ahead of large spills for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 21908-53-2
Page 4 of 4
MERCURIC OXIDE
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl GOOD/LIMITED**
Neoprene GOOD/LIMITED**
Nitrile GOOD/LIMITED**
PVC GOOD/LIMITED**
Viton/Neoprene POOR/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 21908-53-2
Page 1 of 3
Emergency First Aid Treatment Guide
for
MERCURIC OXIDE
(21908-53-2)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Red or orange-red heavy crystalline powder, yellow when finely
powdered.
Odor - None.
Commercial Form - Solid in 100-lb drums.
Uses - Chemical intermediate, analytical reagent, pigment and glass modifier,
polishing compound, paint antifouler, antiseptic, fungicide, dry cell
batteries, cosmetics.
Materials to Avoid - Reducing agents, inorganic acids, water (except for use in
emergency life support).
Caution: Extreme temperatures (in excess of 500 degrees C, may decompose
mercuric oxide into mercury and oxygen. Avoid sources of extre,.-te heat.
Other Names - Red mercuric oxide, yellow mercury oxide, Natural Monotroydite,
Santar.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, milk, activated charcoal,
saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate, diazepam,
phenytoin, phenobarbital, penicillamine, dimercaprol.
-------
EFATG
CAS Registry Number: 21908-53-2
Page 2 of 3
MERCURIC OXIDE
Signs and Symptoms of Acute Mercuric Oxide Exposure:
Signs and symptoms of acute exposure to mercuric oxide may be severe and
include increased salivation, foul breath, inflammation and ulceration of the
mucous membranes, abdominal pain, and bloody diarrhea. Oliguria (scanty
urination), anuria (suppression of urine formation), and acute renal failure
may be noted. Weak pulse, seizures, psychic disturbances, circulatory
collapse, chest pain, and dyspnea (shortness of breath) may be observed.
Dermal exposure may result in dermatitis (red, inflamed skin).
Emergency Life-Support Procedures:
Acute exposure to mercuric oxide may require decontamination and life support
for the victims. Emergency personnel should wear protective clothing
appropriate to the type and degree of contamination. Air-purifying or
supplied-air respiratory equipment should also be worn, as necessary. Rescue
vehicles should carry supplies such as plastic sheeting and disposable plastic
bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to mercuric oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to mercuric oxide.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
-------
EFATG
CAS Registry Number: 21908-53-2
Page 3 of 3
MERCURIC OXIDE
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas for 15 minutes with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz
or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults,
250 mL (8 oz or 1 cup). Water or milk should be given only if victims are
conscious and alert.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
CAS Registry Number: 21923-23-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLORTHIOPHOS
CAS Registry Number: 21923-23-9
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 150) Phosphorothioic
Acid, O,O-Diethyl O-((2,5-Dichloro-4-Methylthio)Phenyl) Ester; Celamerck
S-2957; Celathion; CM S 2957; O-(Dichloro(Methylthio)Phenyl) O,O-Diethyl
Phosphorothioate (3 isomers); O,O-Diethyl-O-2,4,5-Dichloro- (Methylthio)Phenyl
Thionophosphate; ENT 27635; OMS 1342; S 2957
Chemical Formula: CnHjgClpaPSj
Molecular Weight: 361.25
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rabbit) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 307-316°F, 153-158°C at 0.013 mmHg (Worthing 1983,
p. 130)
Specific Gravity (H2O=1): 1.345 at 20°C (Worthing 1983, p. 130)
Vapor Pressure (mmHg): 0.0004 at 25°C (Worthing 1983, p. 130)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 0.3 mg/liter (Worthing 1983, p. 130)
-------
CAS Registry Number: 21923-23-9
Page 2 of 4
CHLORTHIOPHOS
SECTION II (continued)
Appearance and Odor: Yellow-brown liquid which tends to crystallize at
less than 25°C (Worthing 1983, p. 130)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
• 'Skin: Yes (Non-Specific — Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Non-Specific - Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): Classified as extremely
hazardous by the World Health Organization (Encyc Occupat Health and Safety
1983, p. 1619) (Non-Specific — Organophosphorus Pesticide) Organic
phosphorus insecticides are absorbed by the skin, as well as by the
respiratory and gastrointestinal tracts. They are cholinesterase
inhibitors (Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn, but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move
containers from fire area if you can do so without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific - Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire (DOT
1984, Guide 55).
-------
CAS Registry Number: 21923-23-9
Page 3 of 4
CHLORTHIOPHOS
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Product discontinued by Celamerck. It is used as an insecticide and
acaricide (Farm Chemicals Handbook 1984, p. C55).
SECTION VII ~ PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Nor. 'Specific - Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them. Do
not touch spilled material; stop leak if you can do so without risk. Use
water spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent material and place into containers for later
disposal. Large spills: dike far ahead of spill for later disposal (DOT
1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
**Based on a chemical analog.
-------
CAS Registry Number: 21923-23-9
Page 4 of 4
CHLORTHIOPHOS
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific — Organophosphorus
Pesticide) Symptoms are headache, giddiness, blurred vision, nervousness,
weakness, nausea, cramps, diarrhea, and discomfort in the chest. Signs
include sweating, tearing, salivation, vomiting, cyanosis, convulsions,
coma, loss of reflexes and loss of sphincter control (Hayes 1982, p. 302).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched but no information found:
Weast 1979
Hawley 1981
Clayton and Clayton 1981-82
Doull 1980
Buchel 1983
Merck 1983
Student 1981
NFPA 1984
Gosselin 1984
Verschueren 1983
Weiss 1980
ACGIH 1984
NIOSH/OSHA 1978
-------
CAS Registry Number: 22224-92-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FENAMIPHOS
CAS Registry Number: 22224-92-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 126) Phosphoramidic
Acid, Isopropyl-, 4-(Methylthio)-m-Tolyl Ethyl Ester; BAY 68138; ENT 27572;
Ethyl 3-Methyl-4-(Methylthio)Phenyl (l-Methylethyl)Phosphoramidate; Ethyl
4-(Methylthio)-m-Tolyl Isopropylphosphoramidate; Isopropylamino-O-Ethyl-(4-
Methylmercapto-3-Methylphenyl) Phosphate; l-(Methylethyl)-Ethyl 3-Methyl-4-
(Methylthio)Phenyl Phosphoramidate; Nemacur; Nemacur P; Phenamiphos;
Phosphoramidic Acid, (1-Methylethyl)-, Ethyl (3-Methyl-4-(Methylthio)Phenyl)
Ester
Chemical Formula: C13H22NOSPS
Molecular Weight: 303.39
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.091 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 10/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.0000000098 at 86°F, 30°C (Farm Chemicals Handbook
1984, p. C161)
Melting Point: 121°F, 49.2°C (Farm Chemicals Handbook 1984, p. C161)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 22224-92-6
Page 2 of 4
FENAMIPHOS
SECTION II (continued)
Solubility in Water: 400 mg/liter (Farm Chemicals Handbook 1984,
p. C161); 700 mg/liter at 20°C (Worthing 1983)
Appearance and Odor: Brown, waxy solid (Farm Chemicals Handbook 1984,
p. C161); colorless solid (Worthing 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: 0.1 mg/m3 (skin) (ACGIH 1986-87, p. 19)
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1376)
Skin: Yes (Sax 1984, p. 1376)
Ingestion: Yes (Sax 1984, p. 1376)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic orally, by inhalation, and by absorption through the skin (Sax 1984,
p. 1376). (Non-Specific -- Parathion) Death may occur from respiratory
failure (Gosselin 1984, p. III-340).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Organophosphorus Pesticide,
n.o.s.) This material may burn, but does not ignite readily. For small
fires, use dry chemical, carbon dioxide, water spray, or foam. For large
fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move container
from fire area if you can do it without risk. Fight fire from maximum
distance. Dike fire control water for later disposal; do not scatter the
material. Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, n.o.s.) Container may explode in heat of fire. Fire and runoff
from fire control water may produce irritating or poisonous gases (DOT
1984, Guide 55).
-------
CAS Registry Number: 22224-92-6
Page 3 of 4
FENAMIPHOS
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Farm Chemicals Handbook 1984, p. C161)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Emits toxic fumes of nitrogen
oxides, phosphorus oxides, and sulfur oxides when heated to decomposition
(Sax 1984, p. 1376).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
This material is used as a nematocide (Farm Chemicals Handbook 1984, p.
C161).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USF
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific ~ Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out
of low areas. Ventilate closed spaces before entering them. Remove and
isolate contaminated clothing at the site. Do not touch spilled material.
Use water spray to reduce vapors. Take up small spills with sand or other
noncombustible absorbent material and place in containers for later
disposal. Take up small, dry spills with clean shovel and place in clean,
dry container. Dike far ahead of large spills for later disposal (DOT
1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 22224-92-6
Page 4 of 4
FENAMIPHOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 22224-92-6
Page 1 of 3
Emergency First Aid Treatment Guide
for
FENAMIPHOS
(22224-92-6)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Colorless solid.
Commercial Form - Brown, waxy solid.
Use - Pesticide.
Caution: Explosion potential is high; containers may explode in heat of fire.
Avoid sources of extreme heat.
Other Names - Bay 68138, ENT 27572, ethyl 3-methyl-4-(methylthio)phenyl (1-
methylethyl)phosphoramidate, Nemacur.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, pralidoxime, diazepam, phenytoin, phenobarbital.
Signs and Symptoms of Acute Fenamiphos Exposure:
Note: Fenamiphos is a cholinesterase inhibitor.
Acute exposure to fenamiphos may produce the following signs and symptoms:
pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and
profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may
also occur. The heart rate may increase following oral exposure or decrease
following dermal exposure. Hypotension (low blood pressure) may occur although
hypertension (high blood pressure) is not uncommon. Chest pain may be noted.
Respiratory symptoms include dyspnea (shortness of breath), respiratory
depression, and respiratory paralysis. Psychosis may occur.
-------
EFATG
CAS Registry Number: 22224-92-6
Page 2 of 3
FENAMIPHOS
Emergency Life-Support Procedures:
Acute exposure to fenamiphos may require decontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to fenamiphos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to fenamiphos.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 22224-92-6
Page 3 of 3
FENAMIPHOS
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of fenamiphos is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Ingestion of fenamiphos may result in sudden onset of seizures
or loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 23135-22-0
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- OXAMYL
CAS Registry Number: 23135-22-0
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 2, p. 910): Oxamimidic Acid,
N',N'-Dimethyl-N-((Methylcarbamoyl)oxy)-l(Methylthio); D-1410;
2-Dimethylamino-l-(Methylthio)Glyoxal O-Methylcarbamoylmonoxime; DPX 1410;
Insecticide-Nematicide 1410; Thioxamyl; Vydate; Methyl 2-(Dimethylamino)-N-
(((Methylamino)Carbonyl)Oxy)-2-Oxoethanimidothioate; S-Methyl
l-(Dimethylcarbamoyl)-N-(Methylcarbamoyl)Oxy)Thioformimidate; Methyl
N',N'-Dimethyl-N-((Methylcarbamoyl)Oxy)-l-Thiooxamimidate; Vydate L Oxamyl
Insecticide/Nematocide (Hayes 1982 Synonyms, p. 457)
N,N-Dimethyl-alpha-Methylcarbamoyloxyimino-
alpha-(Methylthio)acetamide
Chemical Formula: C7H13N3OSS
Molecular Weight: 219.29
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(raO 0.17 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00023 at 25°C (Hayes 1982, p. 457)
Melting Point: 212-216°F, 100-102°C; changes to form melting at
226-230°F, 108-110°C (Hayes 1982, p. 457)
-------
CAS Registry Number: 23135-22-0
Page 2 of 4
OXAMYL
SECTION II (continued)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Solubility 28 g/100 g at 25°C (Farm Chemicals
Handbook 1984, p. C170)
Appearance and Odor: White, crystalline solid (Farm Chemicals Handbook
1984, p. C170) with slight sulfurous odor (Hayes 1982, p. 457).
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
'iDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1174)
Skin: Yes (Gosselin 1984, p. H-308)
Ingestion: Yes (Hayes 1982, p. 458)
Health Hazards (Acute, Delayed, and Chronic): Classified by the World
Health Organization as highly hazardous (Encyc Occupat Health and Safety
1983, p. 1622). Has also been rated as extremely to super-toxic (Gosselin
1984, p. 11-308). Acute oral exposure (ingestion) to oxamyl has caused
death (Hayes 1982, p. 458). Oxamyl is a potent cholinesterase inhibitor
(Gosselin 1984, p. 11-308).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is a solid carbamate pesticide (Hayes 1982,
p. 457). Extinguish fire using agent suitable for type of surrounding
fire, as the material itself does not burn or burns with difficulty. Use
water in flooding quantities as a fog. Use alcohol foam, carbon dioxide or
dry chemical (Student 1981, p. 104).
Special Fire Fighting Procedures: This is a solid carbamate pesticide
(Hayes 1982, p. 457). Move container from fire area. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
-------
CAS Registry Number: 23135-22-0
Page 3 of 4
OXAMYL
SECTION IV (continued)
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits toxic fumes of nitrogen oxides and sulfur oxides (Sax 1984, p. 1174).
This is a solid carbamate pesticide (Hayes 1982, p. 457). Container may
explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V « REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Hayes 1982, p. 457)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition,
hazardous fumes of nitrogen oxides and sulfur oxides may be emitted (Sax
1984, p. 1174).
Hazardous Polymerization: May Occur Not Found:
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Used as an insecticide, nematicide and ar iricide on many field crops,
vegetables, fruits, and ornamentals (Farm Chemicals Handbook 1984, p.
C170).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This is a solid carbamate pesticide (Hayes 1982, p. 457). Keep unnecessary
people away; isolate hazard areas and deny entry. Stay upwind, keep out of
low areas. Do not touch spilled material, or breathe the vapors,
dusts or fumes from burning materials. Do not handle broken packages
without protective equipment. Wash away any material that may have
contacted the body with soap and water (Student 1981, p. 104;
DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 23135-22-0
Page 4 of 4
OXAMYL
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 23135-22-0
Page 1 of 3
Emergency First Aid Treatment Guide
for
OXAMYL
(23135-22-0)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - White, crystalline solid.
Odor - Slightly sulfurous.
Commercial Forms - Water-soluble liquid or granules.
Use - Pesticide.
Other Names - Oxamil, Thioxamyl, Vydate, 2-dimethylamino-l-(methylthio)glyoxal
O-methylcarbamoylmonoxime.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
atropine, diazepam, phenytoin, protopam.
Signs and Symptoms of Acute Oxamyl Exposure:
Acute exposure to oxamyl usually leads to a cholinergic crisis. Signs and
symptoms may include increased salivation, lacrimation (tearing),
perspiration, spontaneous defecation, and spontaneous urination. Pinpoint
pupils, blurred vision, tremor, muscle twitching, mental confusion,
convulsions, and coma may occur. Gastrointestinal symptoms include abdominal
pain, diarrhea, nausea, and vomiting. Bradycardia (slow heart rate) is common.
Dyspnea (shortness of breath) and pulmonary edema may also occur.
-------
EFATG
CAS Registry Number: 23135-22-0
Page 2 of 3
OXAMYL
Emergency Life-Support Procedures:
Acute exposure to oxamyl may require decontamination and life support for the
victims. Emergency personnel should wear protective clothing appropriate to
the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to oxamyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to oxamyl.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. Transport to a health care facility.
-------
EFATG
CAS Registry Number: 23135-22-0
Page 3 of 3
OXAMYL
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of oxamyl is unknown or suspected to be greater than 30 minutes,
do not induce vomiting and proceed to Step 4. Ipecac should not be
administered to children under 6 months of age.
Warning: Ingestion of oxamyl may result in sudden onset of seizures or
loss of consciousness. Syrup of Ipecac should be administered only if
victims are alert, have an active gag-reflex, and show no signs of
impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility.
-------
CAS Registry Number: 23422-53-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- FORMETANATE HYDROCHLORIDE
CAS Registry Number: 23422-53-9
Synonyms: Formetanate; Carbamic Acid, Methyl-, Ester with
N'-(m-Hydroxyphenyl)-N,N-Dimethylformamidine, Monohydrochloride; Carzol; Carzol
SP; ENT 27566; EP 332; Formetanate Monohydrochloride;
m-(((Dimethylamino)Methylene)Amino)Phenyl Methylcarbamate Hydrochloride;
Methanimidamide, N,N-Dimethyl-N'-(3-(((Methylamino)Carbonyl)Oxy)Phenyl)-,
Monohydrochloride; N,N-Dimethyl-N'-(3-(((Methylamino)Carbonyl)Oxy)Phenyl)
methanimidamide; Schering 36056; SN 36056
Chemical Formula: CnH15NsO2 C1H
Molecular Weight: 257.8
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.16 mg/liter/1 hour (*NIOSH/RTECS 1985)
TPQ: 500/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00000002 (Worthing 1983)
Melting Point: 392-396°F, 200-202°C (decomposes) (Farm Chemicals Handbook
1983, p. C46)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 23422-53-9
Page 2 of 4
FORMETANATE HYDROCHLORIDE
SECTION II (continued)
Solubility in Water: Greater than 50% (*Spencer 1973)
f
Appearance and Odor: White powder with a faint odor (*Martin and Worthing
1974)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Carbamate)
(Doull 1980, p. 375)
Skin: No (Gosselin 1984, p. 11-306)
Ingestion: Yes (Non-Specific -- Carbamate)
(Doull 1980, p. 375)
Health Hazards (Acute, Delayed, and Chronic): Extremely toxic to humans.
Not absorbed through contact with skin. Inhalation or ingestion may cause
poisoning. Inhibits cholinesterase activity so effects are in relation to
action on nervous system and can result in death (*Rumack 1975 to Present;
Gosselin 1984, p. 11-306).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamates Pesticide, Solid,
n.o.s.) Extinguish fire using agent suitable for type of surrounding fire,
as the material itself does not burn or burns with difficulty. Use water
in flooding quantities as a fog. Use alcohol foam, carbon dioxide, or dry
chemical (Student 1981, p. 104).
Special Fire Fighting Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Wear self-contained breathing apparatus when fighting fire
involving this material (Student 1981, p. 104). Move container from fire
area if you can do it without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
-------
CAS Registry Number: 23422-53-9
Page 3 of 4
FORMETANATE HYDROCHLORIDE
SECTION IV (continued)
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. Container may explode in heat of fire (DOT 1984, Guide
55).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (*Spencer 1973)
Conditions to Avoid: Hydrolyzed at pH less than 4 (*Martin and
Worthing 1974)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to'Avoid: Not Found
SECTION VI - USE INFORMATION
Plant insecticide, acaricide, and miticide (*Martin and Worthing 1974,
*SRI).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific ~ Carbamate Pesticide, Solid, n.o.s.) Keep unnecessary
people away; isolate hazard areas and deny entry. Stay upwind and keep out
of low areas. Do not touch spilled material or breathe the dusts, vapors,
or fumes from burning materials. Do not handle broken packages
without protective equipment. Wash away any material that may have
contacted the body with soap and water (Student 1981, p. 104;
DOT 1985, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 23422-53-9
Page 4 of 4
FORMETANATE HYDROCHLORIDE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Diarrhea, nausea, vomiting, excessive
salivation, headache, pinpoint pupils and uncoordinated muscle movements
are all common symptoms (*Rumack 1975 to Present).
Emergency and First Aid Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Move the victim to fresh air and monitor for respiratory
distress. Although it is not absorbed through contact with the skin
(Gosselin 1984, p. H-306) it is advisable to flush skin or eyes with
running water for at least 15 minutes in case of contact. Remove all
contaminated clothing (DOT 1984, Guide 55).
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CAS Registry Number: 23505-41-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PIRIMIFOS-ETHYL
CAS Registry Number: 23505-41-1
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 150) Pirimiphos- Ethyl;
Phosphorothioic Acid, O,O-Diethyl O-(2-(Diethylamino)-6-Methyl-4- Pyrimidinyl)
Ester; O-(2-(Diethylamino)-6-Methyl-4-Pyrimidinyl) O,O-Diethyl
Phosphorothioate; 2-Diethylamino-6-Methylpyrimidin-4-yl Diethylphosphoro-
thionate; O,O-Diethyl O-(2-Diethylamino-6-Methyl-4-Pyrimidinyl)
Phosphorothioate; Fernex; Pirimifosethyl; PP211; Primicid; Primotec; Prinicid;
Phosphorothioic Acid, O-(2-(Diethylamino)-6-Methyl-4-Pyrimidinyl) O,O-Diethyl
Ester
Chemical Formula: C13H24N3O3PS
Molecular Weight: 333.43
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (cat)
25 mg/kg (*NIOSH/RTECS 1985)
TPQ: 1,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): 1.14 at 20°C (Merck 1983, p. 1082)
Vapor Pressure (mmHg): 0.00029 at 25°C (Merck 1983, p. 1082)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
-------
CAS Registry Number: 23505-41-1
Page 2 of 4
PIRIMIFOS-ETHYL
SECTION II (continued)
Solubility in Water: Less than 1 mg/liter at 30°C (Merck 1983, p. 1082)
Appearance and Odor: Straw colored liquid (Merck 1983, p. 1082)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organic Phosphorus
Pesticides) (Hayes 1982, p. 301)
Skin: Yes (Sax 1984, p. 1000)
Ingestion: Yes (Sax 1984, p. 1000)
Health Hazards (Acute, Delayed, and Chronic): Pirimifos-ethyl is an
organophosphorus pesticide (Encyc Occupat Health and Safety 1983, p. 1622)
and is absorbed by the skin, as well as by the respiratory and
gastrointestinal tracts. It is a cholinesterase inhibitor, acting on the
nervous system (Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Like other organophosphorus pesticides (Encyc
Occupat Health and Safety 1983, p. 1622), this material may burn, but does
not ignite readily. For small fires, use dry chemical, carbon dioxide,
water spray, or foam. For large fires, use water spray, fog, or foam (DOT
1984, Guide 55).
Special Fire Fighting Procedures: Use procedures for organophosphorus
pesticides (Encyc Occupat Health and Safety 1983, p. 1622). Stay upwind;
keep out of low areas. Move containers from fire area if you can do it
without risk. Fight fire from maximum distance. Dike fire control water
for later disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: As with other organophosphorus
pesticides (Encyc Occupat Health and Safety 1983, p. 1622), container may
explode in heat of fire (DOT 1984, Guide 55). Heat may cause decomposition
and evolution of highly toxic fumes of phosphorus oxides, nitrogen oxides
and sulfur oxides (Sax 1984, p. 1000).
-------
CAS Registry Number: 23505-41-1
Page 3 of 4
PIRIMIFOS-ETHYL
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Decomposes above 130°C (Merck 1983, p. 1082)
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur
oxides (Sax 1984, p. 1000).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Pirimifos-ethyl is an organophosphorus pesticide (Encyc Occupat Health and
Safety 1983, p. 1622).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
As with other organophosphorus pesticides (Encyc Occupat Health and Safety
1983, p. 1622), stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Do not touch spilled material; stop leak
if you can do so without risk. Use water spray to reduce vapors. Small
spills: absorb with sand or other non-combustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 23505-41-1
Page 4 of 4
PIRIMIFOS-ETHYL
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: As with other organophosphorus pesticides
(Encyc Occupat Health and Safety 1983, p. 1622), symptoms are secondary to
cholinesterase inhibition: headache, giddiness, blurred vision,
nervousness, weakness, nausea, cramps, diarrhea, and discomfort in the
chest. Other signs include sweating, tearing, salivation, vomiting,
cyanosis, convulsions, coma, loss of reflexes and loss of sphincter control
(Hayes 1982, p. 302).
Emergency and First Aid Procedures: Treat as organophosphorus pesticide
(Encyc Occupat Health and Safety 1983, p. 1622). Move victim to fresh air;
call emergency medical care. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact
with material, immediately flush skin or eyes with running water for at
least 15 minutes. Speed in removing material from skin is of extreme
importance. Remove and isolate contaminated clothing and shoes at the
site. Keep victim quiet and maintain normal body temperature. Effects may
be delayed; keep victim under observation (DOT 1984, Guide 55).
COMMENTS
Sources searched, no information found:
Farm Chemicals Handbook 1984
Buchel 1983
Clayton and Clayton 1981-82
-------
CAS Registry Number: 24017-47-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - TRIAZOFOS
CAS Registry Number: 24017-47-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 153): Phosphorothioic
Acid, O,O-Diethyl O-(l-Phenyl-l,2,4-Triazolyl) Ester; O,O-Diethyl
O-(l-Phenyl-lH-l,2,4-Triazol-3-yl)Phosphorothioate; HOE 2960; HOE 2960 OJ;
Hostathion; l-Phenyl-3-(O,O-Diethyl Thionophosphoryl)-l,2,4-Triazole;
l-Phenyl-l,2,4-Triazolyl-3-(O,O-Diethyl Thionophosphate); Triazophos
Chemical Formula: C^H^NgOjPS
Molecular Weight: 313.34
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.28 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Decomposes before boiling (Farm Chemicals Handbook 1984,
p. C123)
Specific Gravity (H2O=1): 1.247 at 20°C/4°C (Worthing 1983)
Vapor Pressure (mmHg): 0.00001 (Worthing 1983)
Melting Point: 32-41°F, 0-5°C for technical grade (Worthing 1983)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 30-40 mg/L at 20°C (Worthing 1983)
-------
CAS Registry Number: 24017-47-8
Page 2 of 4
TRIAZOFOS
SECTION II (continued)
Appearance and Odor: Yellowish oil (Worthing 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Skin: Yes (Non-Specific — Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Encyc Occupat Health and Safety
1983, p. 1622)
Health Hazards (Acute, Delayed, and Chronic): This is an organophosphate
pesticide (Buchel 1983, p. 166). This material is a cholinesterase
inhibitor and acts on the central nervous system (Buchel 1983, pp.
165-166). Organic phosphorus insecticides are absorbed by the skin as well
as by the respiratory and gastrointestinal tracts (Hayes 1982, p. 301).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This is an organophosphate pesticide (Buchel 1983,
p. 166). Extinguish with dry chemical, carbon dioxide, water spray, fog,
or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures: This is an organophosphate pesticide
(Buchel 1983, p. 166). Keep unnecessary people away; isolate hazard area
and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Wear positive pressure breathing apparatus
and special protective clothing. Remove and isolate contaminated clothing
at the site. Move container from fire area if you can do it without risk.
Fight fire from maximum distance. Dike fire control water for later
disposal; do not scatter the material (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: This is an organophosphate pesticide
(Buchel 1983, p. 166). Some of these materials may burn but none of them
-------
CAS Registry Number: 24017-47-8
Page 3 of 4
TRIAZOFOS
SECTION IV (continued)
ignite readily. Container may explode in heat of fire. Fire may produce
irritating or poisonous gases (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Degraded by acids and alkalis (Farm
Chemicals Handbook 1984, p. C123).
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI --USE INFORMATION
This material is a pesticide used to control insects, mites, and nematodes
(Buchel 1983, p. 166). Not registered as a pesticide in the U.S. (USEPA/
Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation and skin contact (see Section III above). This is an
organophosphate pesticide (Buchel 1983, p. 166). Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel, place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 24017-47-8
Page 4 of 4
TRIAZOFOS
SECTION VIII (continued)
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: This is an organophosphate pesticide
(Buchel 1983, p. 166). Symptoms include headache, giddiness, nervousness,
blurred vision, weakness, nausea, cramps, diarrhea, chest pain, sweating,
fixed pinpoint pupils, tearing,'salivation, vomiting, muscle weakness and
irregular heart beat (Hayes 1982, p. 301).
Emergency and First Aid Procedures: This is an organophosphate pesticide
(Buchel 1983, p. 166). Move victim to fresh air; call emergency medical
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 24934-91-6
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- CHLORMEPHOS
CAS Registry Number: 24934-91-6
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 139) Phosphorodithioic
Acid, S-(Chloromethyl) O,O-Dimethyl Ester; S-(Chloromethyl) O,O-Diethyl
Phosphorodithioate; S-Chloromethyl O,O-Diethyl Phosphorothiolothionate;
Dotan; MC 2188
Chemical Formula: C5H12C1O2PS2
Molecular Weight: 234.71
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral (rat)
7 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listtl (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 178-185°F, 81-85°C at 0.1 mmHg (Worthing 1983)
Specific Gravity (H2O=1): 1.260 (Farm Chemicals Handbook 1984,
p. C51)
Vapor Pressure (mmHg): 0.0056 at 30°C (Worthing 1983)
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Slightly soluble (Farm Chemicals Handbook 1984, p.
C51); 60 mg/liter at 20°C (Worthing 1983)
-------
CAS Registry Number: 24934-91-6
Page 2 of 4
CHLORMEPHOS
SECTION II (continued)
Appearance and Odor: Liquid (Farm Chemicals Handbook 1984, p. C51);
colorless (Worthing 1983)
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Organophosphorus
Pesticide.) (Hayes 1982, p. 301)
Skin: "Yes (Non-Specific— Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Ingestion: Yes (Non-Specific -- Organophosphorus
Pesticide) (Hayes 1982, p. 301)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific --
Organophosphorus Pesticide, Liquid, n.o.s.) This material is poisonous; it
may be fatal if inhaled, swallowed, or absorbed through the skin (DOT 1984,
Guide 55).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Organophosphorus Pesticide,
Liquid, n.o.s.) This material may burn, but does not ignite readily. For
small fires, use dry chemical, carbon dioxide, water spray, or foam. For
large fires, use water spray, fog, or foam (DOT 1984, Guide 55).
Special Fire Fighting Procedures:(Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move
container from fire area if you can do it without risk. Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter the material. Wear positive pressure breathing apparatus and
special protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire
and runoff from control water may produce irritating or poisonous gases
(DOT 1984, Guide 55).
-------
CAS Registry Number: 24934-91-6
Page 3 of 4
CHLORMEPHOS
SECTION IV (continued)
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (Farm Chemicals Handbook 1984, p. C51).
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
This material is a soil insecticide (Farm Chemicals Handbook 1984, p. C51).
Not registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Organophosphorus Pesticide, Liquid, t .o.s.) Stay upwind;
keep out of low areas. Ventilate closed spaces before jntering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material. Use water spray to reduce vapors. Take up small spills with
sand or other noncombustible absorbent material and place in containers for
later disposal. Dike far ahead of large spills for later disposal (DOT
1984, Guide 55).
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
**Based on a chemical analog.
-------
CAS Registry Number: 24934-91-6
Page 4 of 4
CHLORMEPHOS
SECTION IX ~ EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: (Non-Specific -- Parathion) Symptoms may
include nausea, vomiting, abdominal cramps, diarrhea, excessive salivation,
headache, giddiness, weakness, muscle twitching, difficult breathing,
blurring or dimness of vision, and loss of muscle coordination. Death may
occur from failure of the respiratory center, paralysis of the respiratory
muscles, intense bronchoconstriction, or all three (Gosselin 1984, p.
III-340).
Emergency and First Aid Procedures: (Non-Specific — Organophosphorus
Pesticide, Liquid, n.o.s.) Move victim to fresh air; call emergency
medical care. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
-------
CAS Registry Number: 26419-73-8
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - CARBAMIC ACID, METHYL-, O-(((2,4-DIMETHYL-l,
3-DITHIOLAN-2-YL)METHYLENE)AMINO)-
CAS Registry Number: 26419-73-8
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 835) 2,4-Dimethyl-
l,3-Dithiolane-2-Carboxaldehyde O-(Methylcarbamoyl)Oxime; 2,4-Dimethyl-
2-Formyl-l,3-Dithiolane Oxime Methylcarbamate; l,3-Dithiolane-2-
Carboxaldehyde, 2,4-Dimethyl-, O-((Methylamino)Carbonyl)Oxime; 1,3-Dithiolane-
2-carboxaldehyde, 2,4-Dimethyl-, O-(Methylcarbamoyl)Oxime; Ent 27696; MBR 6168;
Tirpate
Chemical Formula: C8H14N2O2S2
Molecular Weight: 234.36
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD60 oral (rat)
1 mg/kg (*NIOSH/TECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II ~ PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 26419-73-8
Page 2 of 3
CARBAMIC ACID, METHYL-, O-(((2,4-DIMETHYL...
SECTION II (continued)
Appearance and Odor: Not Found
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV ~ FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
. NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
-------
CAS Registry Number: 26419-73-8
Page 3 of 3
CARBAMIC ACID, METHYL-, O-(((2,4-DIMETHYL...
SECTION V (continued)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Nematocide; product discontinued (Farm Chemicals Handbook 1984, p. C227).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
The following sources were searched but no information was found:
Clayton and Clayton 1981-82
Merck 1983
Sax 1984
Verschueren 1983
Weast 1979
Hayes 1982
Hawley 1981
-------
CAS Registry Number: 26628-22-8
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
, Revision: November 30, 1987
CHEMICAL IDENTITY -- SODIUM AZIDE (Na(N3))
CAS Registry Number: 26628-22-8
Synonyms: Azide; Azium; Kazoe; NSC 3072; Smite; Sodium Azide; U-3886;
Hydrazoic Acid, Sodium Salt
Chemical Formula: NsNa
Molecular Weight: 65.02 (*NIOSH 1985)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 dermal
(rabbit) 20 mg/kg (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1000 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Decomposes in vacuum (*Weast 1979)
Specific Gravity (H2O=1): 1.846 at 20°C (*Weast 1979)
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposes at 275°C to sodium and nitrogen (*Weast 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 42g in 100 mL at 17°C (DASE 1980, p. 827)
Appearance and Odor: Colorless hexagonal crystals or white crystalline
solid which is odorless (*Weast 1979; *Patty 1963; *Weed Science Society of
America 1979)
-------
CAS Registry Number: 26628-22-8
Page 2 of 4
SODIUM AZIDE (Na(N3))
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Ceiling: 0.3 mg/ms (0.1 ppm) (ACGIH 1984, p. 31)
IDLH: Not Found
Other Limits Recommended: Not found
Routes of Entry: Inhalation: Yes (DASE 1980, p. 827)
Skin: Yes (Sax 1984, p. 2412)
Ingestion: Yes (Sax 1984, p. 2412)
Health Hazards (Acute, Delayed, and Chronic): Can cause death by
affecting the central nervous system. Contact may cause burns to skin and
eyes (*Gosselin 1976).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not flammable (Weiss 1980, p. 811)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: If material is on fire or involved in fire, use
water in flooding quantities as fog. Cool all affected containers with
flooding quantities of water. Apply water from as far a distance as
possible. Use foam, carbon dioxide or dry chemical (Student 1981, p. 462).
Small fires: dry chemical, carbon dioxide, water spray, or foam. Large
fires: water spray, fog, or foam. Move container from fire area if you
can do so without risk. Spray cooling water on containers that are exposed
to flames until well after fire is out. For massive fire in cargo area,
use unmanned hose holder or monitor nozzles; if this is impossible,
withdraw from area and let fire burn (DOT 1984, Guide 56).
Special Fire Fighting Procedures: Personnel protection: Avoid breathing
dusts and fumes from burning material. Avoid bodily contact with the
material. Wear boots, protective gloves and goggles. Do not handle broken
packages without protective equipment. Wash away any material which may
have contacted the body with copious amounts of water or soap and water.
Evacuation: If fire becomes uncontrollable or container is exposed to
direct flame, evacuate for a radius of 2500 feet (Student 1981, p. 462).
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering.
Wear positive pressure breathing apparatus and special protective clothing
(DOT 1984, Guide 56).
Unusual Fire and Explosion Hazards: When heated to decomposition, it
-------
CAS Registry Number: 26628-22-8
Page 3 of 4
SODIUM AZIDE (Na(N3))
SECTION IV (continued)
emits very toxic fumes of nitrogen oxides; explosive (Sax 1984, p. 2412).
Forms explosive-sensitive materials with some metals such as lead, silver,
mercury or copper. May form toxic hydrazoic acid fumes in fire.
Containers may explode in fire (Weiss 1980, p. 811).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Yes (Sax 1984, p. 2412)
Stable:
Conditions to Avoid: Acids (Weiss 1980, p. 811)
Incompatibility (Materials to Avoid): Acids (Weiss 1980, p. 811); benzoyl
chloride and potassium hydroxide; bromine; carbon disulfide; copper; lead;
nitric acid; barium carbonate; sulfuric acid; chromium (II) hypochlorite,
dimethyl sulfate, water, dibromomalononitrile (Sax 1984, p. 2412). Lead,
silver, copper, mercury (Weiss 1980, p. 811).
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen oxides (Sax 1984, p. 2412).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Yes (Weiss 1980, p. 811)
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATJ ,"»N
Air bag inflation; preservative in diagnostic medicinals; intermediate in
explosives manufacturing (Hawley 1981, p. 933). Broad-spectrum biocide,
herbicide, fungicide, nematicide, soil fumigant and insecticide (*Weed
Science Society of America 1979). Used in organic synthesis (*USEPA 1977),
water pollution analysis (*Bretherick 1979), and in the chemical industry
for various manufactured products including sponge rubber and latexes
(*Sittig 1981).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation of this material (see Section III above). In case of
contact, immediately flush skin or eyes with water for at least 15 minutes.
Remove and isolate contaminated clothing. Do not touch spilled material;
stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material
and place into containers for later disposal. Small dry spills: with
clean shovel place material into clean, dry container and cover; move
containers from spill area. Large spills: dike far ahead of spill for
later disposal (DOT 1984, Guide 56).
-------
CAS Registry Number: 26628-22-8
Page 4 of 4
SODIUM AZIDE (Na(Ns))
SECTION VII (continued)
If material is not on fire and not involved in fire, keep sparks, flames,
and other sources of ignition away. Keep material out of water sources and
sewers (Student 1981, p. 462).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Can cause death by affecting the central
nervous system. Contact on skin causes redness and pain. Contact with
eyes causes redness, pain, and blurred vision. Inhalation or ingestion
causes dizziness, weakness, blurred vision, slight shortness of breath,
hypotension, slowed heart rate, abdominal pain and spasms. Serious cases
of exposure may result in convulsions, unconsciousness and death (*Patty
1963; *Gosselin 1976; *USEPA 1977; Weiss 1980, p. 811; DASE 1980, p. 827).
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact with material,
immediately flush skin or eyes with running water for at least 15 minutes.
Speed in removing material from skin is of extreme importance. Remove and
isolate contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 56).
-------
CAS Registry Number: 27137-85-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- TRICHLORO(DICHLOROPHENYL)SILANE
CAS Registry Number: 27137-85-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 591) Silane,
(Dichlorophenyl)Trichloro-; Dichloro Phenyl Trichloro Silane
Chemical Formula: C6HsCl5Si
Molecular Weight: 280.43
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LClow inhalation
(mouse,mammal) 0.08 mg/liter/2 hours (*NIOSH/RTECS 1985)
TPQ: 500 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 500°F, 260°C (Sax 1984, p. 962)
Specific Gravity (H2O=1): 1.562 (Sax 1984, p. 962)
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Straw colored liquid with pungent odor (Student
1981, p. 187)
-------
CAS Registry Number: 27137-85-5
Page 2 of 4
TRICHLORO(DICHLOROPHENYL)SILANE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 962)
Skin: Yes (Hawley 1981, p. 338)
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Contact causes burns to
skin and eyes. If inhaled, it may be harmful (DOT 1984, Guide 60). Fire
may produce irritating or poisonous gases. The compound is highly toxic by
inhalation (Sax 1984, p. 962) and is a strong irritant to the skin and eyes
(Hawley 1981, p. 338).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 286°F (Sax 1984, p. 962)
Flammable Limits: Material will burn but requires some effort to ignite
(Student 1981, p. 187).
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This material may react violently with water.
Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam
(DOT 1984, Guide 60). Also dry sand may be used (Student 1981, p. 187).
Special Fire Fighting Procedures: Keep unnecessary people away; isolate
hazard area and deny entry. Stay upwind; keep out of low areas. Wear
self-contained (positive pressure if available) breathing apparatus and
full protective clothing. Move container from fire area if you can do so
without risk. Spray cooling water on containers that are exposed to flames
until well after fire is out (DOT 1984, Guide 60). Do not use water on
material itself. Use spray to absorb vapors (Student 1981, p. 187).
Unusual Fire and Explosion Hazards: This material may burn but does not
ignite readily. Flammable/poisonous gases may accumulate in tanks and
hopper cars (DOT 1984, Guide 60). This material may ignite combustibles
(wood, paper, oil, etc.). The compound is a slight fire hazard when
exposed to heat or flame (Sax 1984, p. 962).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 27137-85-5
Page 3 of 4
TRICHLORO(DICHLOROPHENYL)SILANE
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: It is decomposed by moisture or
water to hydrochloric acid with the evolution of heat (Student 1981, p.
187).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Intermediate for silicones (Hawley 1981, p. 338).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other combustible absorbent material and
place into containers for later disposal. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 60). Neutralize spilled material
with crushed limestone, soda ash, or lime. Keep sparks, flames, and other
sources of ignition away. Use water spray to knock down vapors. Do not
use water on material itself. Avoid breathing vapors. Keep upwind.
Avoid bodily contact with the material. Do not handle broken
packages without protective equipment (Student 1981, p. 187).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Move victim to fresh air; call
emergency medical care. Remove and isolate contaminated clothing and shoes
-------
CAS Registry Number: 27137-85-5
Page 4 of 4
TRICHLORO(DICHLOROPHENYL)SILANE
SECTION IX (continued)
at the site. In case of contact with material, immediately flush skin or
eyes with running water for at least 15 minutes. Keep victim quiet and
maintain normal body temperature (DOT 1984, Guide 60).
COMMENT
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Weast 1979
Merck 1983
NFPA 1984
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 28347-13-9
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- XYLYLENE BICHLORIDE
CAS Registry Number: 28347-13-9
Synonyms (SANSS 1983 Synonyms): Benzene, bis(Chloromethyl)-; Xylene,
alpha.alpha-Dichloro-; alpha,alpha'-Dichloroxylene;
bis(Chloromethyl)Benzene; Dichloroxylylene; Xylylene Chloride
(Weast 1980 Synonyms, p. C-149) Benzene, l,2-bis(Chloromethyl)-; o-Xylylene
Chloride; Benzene, l,3-bis(Chloromethyl)-; m-Xylylene Chloride; Benzene,
l,4-bis(Chloromethyl)-; p-Xylylene Chloride
Chemical Formula: C8H8C12 (Weast 1979, p. C-149)
Molecular Weight: 175.07 (Weast 1979, p. C-149)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.2 mg/liter/4 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: o-Isomer: 462-466°F, 239-241°C; m-Isomer: 482-491°F,
250-255°C; p-Isomer: 464-473°F, 240-245°C (decomposes) (Weast 1979, p.
C-149)
Specific Gravity (H2O=1): o-Isomer: 1.393 at 0°C; m-Isomer: 1.302 at
20°C; p-Isomer: 1.417 at 0°C (Weast 1979, p. C-149)
Vapor Pressure (mmHg): Not Found
Melting Point: o-Isomer: 131°F, 55°C; m-Isomer: 93.6°F, 34.2°C;
p-Isomer: 212°F, 100°C (Weast 1979, p. C-149)
Vapor Density (AIR=1): Not Found
-------
CAS Registry Number: 28347-13-9
Page 2 of 4
XYLYLENE DICHLORIDE
SECTION II (continued)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Weast 1979, p. C-149)
Appearance and Odor: o- and p-Isomers: crystalline solids (Weast 1980,
p. C-149).
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: "Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
-------
CAS Registry Number: 28347-13-9
Page 3 of 4
XYLYLENE DICHLORIDE
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific — Poisonous Solid, n.o.s.) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Do not touch spilled material; stop leak if you can do so without risk.
Small spills: absorb with sand or other noncombustible absorbent
material and place into containers for later disposal. Large spills:
dike spill for later disposal (DOT 1984, Guide 53).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene POOR/LIMITED**
CPE GOOD/LIMITED**
Neoprene POOR/LIMITED**
PE POOR/LIMITED**
PVC POOR/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
*Based on qualitative performance information.
**Based on a chemical analog.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific — Poisonous Solid,
n.o.s.) Move victim to fresh air; call emergency medical care. In case of
-------
CAS Registry Number: 28347-13-9
Page 4 of 4
XYLYLENE BICHLORIDE
SECTION IX (continued)
contact with material, immediately flush skin or eyes with running water
for at least 15 minutes. Remove and isolate contaminated clothing and
shoes at the site (DOT 1984, Guide 53).
COMMENTS:
Sources searched but no information found:
NIOSH/RTECS 1983
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1986
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 28772-56-7
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY ~ BROMADIOLONE
CAS Registry Number: 28772-56-7
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 965): Coumarin,
3-(3-(4'-Bromo-l,l'-Biphenyl-4-yl)-3-Hydroxy-l-Phenylpropyl)-4-Hydroxy-;
2H-l-Benzopyran-2-one, 3-(3-(4'-Bromo(l,l'-Biphenyl)-4-yl)-3-Hydroxy-l-
Phenylpropyl)-4-Hydroxy-; Bromadialone; Coumarin, 3-(alpha-(p-(p-Bromophenyl)-
beta-Hydroxyphenethyl)Benzyl)-4-Hydroxy-; Maki; Ratimus (Tamogram); Super-Caid;
Super-Rozol; (Farm Chemicals Handbook 1984, p. C-36): Bromone; Canadien 2000;
Contrac; Termus; Sup'operats
Chemical Formula: CsoH2sBrO4
Molecular Weight: 527.44
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 1.125 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: 392-410°F, 200-210°C (Merck 1983, p. 191)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Insoluble (Merck 1983, p. 191)
-------
CAS Registry Number: 28772-56-7
Page 2 of 4
BROMADIOLONE
SECTION II (continued)
Appearance and Odor: Yellowish powder (Merck 1983, p. 191)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 517)
Health Hazards (Acute, Delayed, and Chronic): The compound is toxic by
oral exposure (Sax 1984, p. 517).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specifiw -- Coumarin Derivative Pesticide,
Solid, n.o.s.) Small fires: dry chemicals, carbon dioxide, water spray or
foam. Large fires: water spray, fog or foam. Move container from fire
area if you can do so without risk. Fight fire from maximum distance.
Dike fire control water for later disposal; do not scatter the material
(DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) This material may burn but does not ignite
readily. Container may explode in heat of fire. Keep unnecessary people
away; isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering them. Wear positive
pressure breathing apparatus and special protective clothing. Remove and
isolate contaminated clothing at the site. If water pollution occurs,
notify appropriate authorities (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific — Coumarin Derivative
Pesticide, Solid, n.o.s.) Fire may produce irritating or poisonous gases.
Runoff from fire control water may give off poisonous gases. Runoff from
fire control or dilution water may cause pollution (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
-------
CAS Registry Number: 28772-56-7
Page 3 of 4
BROMADIOLONE
SECTION V ~ REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits toxic fumes of bromine containing compounds (Sax 1984, p. 517).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI « USE INFORMATION
Anticoagulant rodenticide (Merck 1983, p. 191). It is bait for rodent
control used against house mice, roof rats, warfarin-resistant Norway rats.
It is also authorized by USDA for use in official establishments operating
under the Federal meat, poultry, shell egg grading and egg products
inspection program (Farm Chemicals Handbook 1984, p. C-36).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Coumarin Derivative, Pesticide, Solid, n.o.s.) Do not
touch spilled material; stop leak if you can do so without risk. Use water
spray to reduce vapors. Small spills: absorb with sand or other
non-combustible absorbent material and place into containers for later
disposal. Small dry spills: with clean shovel place material into clean,
dry container and cover; move containers from spill area. Large spills:
dike far ahead of spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SUIT MATERIAL PERFORMANCE (Based on EPA/USCG "Guidelines", 1987)
(Chemical Resistance/Amount of Data)
Butyl/Neoprene GOOD/LIMITED**
Viton GOOD/LIMITED**
Viton/Neoprene GOOD/LIMITED**
**Based on a chemical analog.
-------
CAS Registry Number: 28772-56-7
Page 4 of 4
BROMADIOLONE
SECTION IX - EMERGENCY TREATMENT INFORMATION
See Emergency First Aid Treatment Guide
-------
EFATG
CAS Registry Number: 28772-56-7
Page 1 of 3
Emergency First Aid Treatment Guide
for
BROMADIOLONE
(28772-56-7)
This guide should not be construed to authorize emergency personnel to
perform the procedures or activities indicated or implied. Care of persons
exposed to toxic chemicals must be directed by a physician or other recognized
authority.
Substance Characteristics:
Pure Form - Yellowish powder.
Commercial Form - 97% pure yellowish powder.
Use - Rodenticide.
Other Names - Bromone; Contrac; coumarin, 3-(3-(4'-bromo-l,l'-biphenyl-4-yl)
-3-hydroxy-l-phenylpropyl)-4-hydroxy; Maki; Ratimus; Super-Caid; Sup'operats;
Termus.
Personal Protective Equipment: See Chemical Profile Section VIII.
Emergency Life-Support Equipment and Supplies That May Be Required:
Compressed oxygen, forced-oxygen mask, soap, water, syrup of Ipecac, activated
charcoal, saline cathartic or sorbitol, normal saline, D5W, Ringer's lactate,
vitamin K (phytonadione).
Signs and Symptoms of Acute Bromadiolone Exposure:
Bromadiolone is an anticoagulant. Hemorrhage is the most common effect and may
be manifested by nose bleeding, gum bleeding, bloody stools and urine,
ecchymoses (extravasations of blood into skin), and hemoptysis (coughing up of
blood). Bruising is heightened. Abdominal and flank pain are also common.
-------
EFATG
CAS Registry Number: 28772-56-7
Page 2 of 3
BROMADIOLONE
Emergency Life-Support Procedures:
Acute exposure to bromadiolone may require dedontamination and life support for
the victims. Emergency personnel should wear protective clothing appropriate
to the type and degree of contamination. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure
to bromadiolone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
4. RUSH to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to bromadiolone.
2. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for
at least IS minutes.
5. Wash exposed skin areas twice with soap and water.
6. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
7. RUSH to a health care facility.
-------
EFATG
CAS Registry Number: 28772-56-7
Page 3 of 3
BROMADIOLONE
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since
ingestion of bromadiolone is unknown or suspected to be greater than
30 minutes, do not induce vomiting and proceed to Step 4. Ipecac should
not be administered to children under 6 months of age.
Warning: Syrup of Ipecac should be administered only if victims are
alert, have an active gag-reflex, and show no signs of impending seizure
or coma. If ANY uncertainty exists, proceed to Step 4.
The following dosages of Ipecac are recommended: children up to 1 year
old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults,
30 mL (1 oz). Ambulate (walk) the victims and give large quantities of
water. If vomiting has not occurred after 15 minutes, Ipecac may be
readministered. Continue to ambulate and give water to the victims. If
vomiting has not occurred within 15 minutes after second administration of
Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert.
Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz)
for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to
conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz)
of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. RUSH to a health care facility.
-------
EPA CHEMICAL PROFILE
CHEMICAL IDENTITY -- METHACRYLO
CAS Registry Number: 30674-80-7
Synonyms (NIOSH/RTECS 1983 Synonyms,
2-Isocyanatoethyl Ester; beta-Isocyanoethyl
Methacrylate; 2-Propenoic Acid, 2-Methyl-,
Chemical Formula: C7H9NOS
Molecular Weight: 155.17
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
fLOXYETHYL ISOCYANATE
Volume 2, p. 670): Methacrylic Acid,
Methacrylate; 2-Isocyanatoethyl
2-Isocyanatoethyl Ester
Toxicity Value Used for Listing
(rat) 0.15 mg/Iitcr/1 hour (*NIQSH/RTECS
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification
Section 313 Listed (Yes or No):
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): No|t Found
Solubility in Water: Not Found
Appearance and Odor: Not Found
CAS Registry Number: 30674-80-7
Page 1 of 4
Date: October 31, 1985
Revision: November 30, 1987
Under Section 302: LC50 inhalation
1985)
under SARA Section 304(a)(2))
No
-------
CAS Registry Number: 30674-80-7
Page 2 of 4
METHACRYLOYLOXYETHYL ISOCYANATE
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Non-Specific — Isocyanates and
Solutions, n.o.s. (Flammable, Poisonous))
(DOT 1984, Guide 57)
Skin: Yes (Non-Specific — Isocyanates and
Solutions, n.o.s. (Flammable, Poisonous))
(DOT 1984, Guide 57)
Ingestion: Yes (Non-Specific ~ Isocyanates and
Solutions, n.o.s. (Flammable, Poisonous))
(DOT 1984, Guide 57)
Health Hazards (Acute, Delayed, and Chronic): (Non-Specific —
Isocyanates and Solutions, n.o.s. (Flammable, Poisonous)) Poisonous; may
be fatal if inhaled, swallowed or absorbed through skin. Contact may cause
burns to skin and eyes (DOT 1984, Guide 57).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific -- Isocyanates and solutions, n.o.s.
(Flammable, Poisonous)) Small fires: dry chemical, carbon dioxide, water
spray, or foam. Large fires: water spray, fog, or foam (DOT 1984, Guide
57).
Special Fire Fighting Procedures: (Non-Specific — Isocyanates and
Solutions, n.o.s. (Flammable, Poisonous)) Keep unnecessary people away;
isolate hazard area and deny entry. Stay upwind; keep out of low areas.
Ventilate closed spaces before entering them. Wear positive pressure
breathing apparatus and special protective clothing. Move container from
fire area if you can do it without risk. Cool containers that are exposed
to flames with water from the side until well after fire is out. Fight
fire from maximum distance. Dike fire control water for later disposal; do
not scatter the material (DOT 1984, Guide 57).
Unusual Fire and Explosion Hazards: (Non-Specific — Isocyanates and
Solutions, n.o.s. (Flammable, Poisonous)) May be ignited by heat, sparks,
or flames. Container may explode in heat of fire. Vapor explosion and
-------
CAS Registry Number: 30674-80-7
Page 3 of 4
METHACRYLOYLOXYETHYL ISOCYANATE
SECTION IV (continued)
poison hazard indoors, outdoors or in sewers. Runoff from fire control or
dilution water may cause pollution (DOT 1984, Guide 57).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific - Isocyanates and Solutions, n.o.s. (Flammable, Poisonous))
Keep unnecessary people away; isolate hazard area and deny entry. Stay
upwind; keep out of low areas. Ventilate closed spaces before entering
them. Shut off ignition sources; no flares, smoking or flames in
hazard area. Do not touch spilled material; stop leak if you can do so
without risk. Use water spray to reduce vapors. Small spills: absorb
with sand or other noncombustible absorbent material and place into
containers for later disposal. Small dry spills: with clean shovel place
material into clean, dry container and cover; move containers from spill
area. Large spills: dike far ahead of spill for later disposal (DOT 1984,
Guide 57).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
-------
CAS Registry Number: 30674-80-7
Page 4 of 4
METHACRYLOYLOXYETHYL ISOCYANATE
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: (Non-Specific -- Isocyanates) Once
the victim has been removed from the contaminated area the treatment is
symptomatic. Oxygen may be administered in acute attacks. The person must
be kept quiet until respiratory symptoms disappear. When there is skin or
mucous membrane contact, the affected areas must be washed copiously (Encyc
Occupat Health and Safety 1983, p. 162).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 39196-18-4
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - THIOFANOX
CAS Registry Number: 39196-18-4
Synonyms: 2-Butanone, 3,3-Dimethyl-l-(Methylthio)-, O-((Methylamino)
Carbonyl)Oxime; 3,3-Dimethyl-l-(Methylthio)-2-Butanone O-((Methylamino)
Carbonyl)Oxime; Dacamox; DS 15647; ENT 27851
Chemical Formula: C9H18N2O2S
Molecular Weight: 218.35
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 8.5 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 100 (pounds)
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): 0.00017 at 25°C (*Worthing 1979)
Melting Point: 133.7-135.5°F, 56.5-57.5°C (*Worthing 1979)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: 5.2 g/liter af22°C (*Worthing 1979)
Appearance and Odor: Thiof anox is a colorless solid with a pungent odor
(*Worthing 1979)
-------
CAS Registry Number: 39196-18-4
Page 2 of 3
THIOFANOX
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Student 1981, p. 104)
Skin: Yes (Student 1981, p. 104)
Ingestion: Yes (Student 1981, p. 104)
Health Hazards (Acute, Delayed, and Chronic): This material is a
carbamate pesticide (Buchel 1983, p. 134). Carbamate pesticides are
moderately to highly toxic (Sax 1984, p. 631). It is a cholinesterase
inhibitor (Gosselin 1984, p. 111-86).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits: Non-flammable (Student 1981, p. 104)
LEL: Not Found
UEL: Not Found
Extinguishing Methods: (Non-Specific — Carbamate Pesticide, Solid,
n.o.s.) Isolate hazard area and deny entry. Stay upwind; keep out of low
areas. Ventilate closed spaces before entering. Use water spray, fog or
foam. Move container from fire area (only without risk). Fight fire from
maximum distance. Dike fire control water for later disposal; do not
scatter material (DOT 1984, Guide 55).
Special Fire Fighting Procedures: (Non-Specific — Carbamate Pesticide,
Solid, n.o.s.) Wear positive pressure breathing apparatus and special
protective clothing (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: (Non-Specific -- Carbamate Pesticide,
Solid, n.o.s.) Container may explode in heat of fire (DOT 1984, Guide 55).
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable:
Stable: Stable at normal storage temperature; reasonably
stable to hydrolysis at less than 30C at pH 5-9
(*Worthing 1979)
-------
CAS Registry Number: 39196-18-4
Page 3 of 3
THIOFANOX
SECTION V (continued)
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of nitrogen and sulfur oxides (Sax 1984, p. 852).
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Systemic insecticide and acaricide (*Worthing 1979)
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
(Non-Specific -- Carbamate Pesticide, Solid, n.o.s.) Do not touch spilled
material; stop leak (only without risk). Use water spray to reduce
vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal.
Large spills: dike far ahead of spill for later disposal (DOT
1981, Guide 55).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting,
abdominal cramps, diarrhea, excessive salivation, sweating, weakness, runny
nose, tightness of chest (inhalation exposure), blurred vision, tearing,
muscle spasm, loss of eye coordination, ocular pain, extreme dilation of
the pupil, loss of muscle coordination, slurring of speech, difficulty in
breathing, excessive respiratory tract mucous, lung fluid buildup, skin
discoloration, and hypertension (*Gosselin 1976).
Emergency and First Aid Procedures: Establish clear airway and administer
oxygen if necessary. Bathe and shampoo victim if skin and hair are
contaminated. If ingested, stomach must be emptied; give syrup of ipecac
to induce vomiting (*Morgan 1976).
-------
CAS Registry Number: 50782-69-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY - PHOSPHONOTHIOIC ACID, METHYL-, S-(2-(BIS
(1-METHYLETHYL)AMINO)ETHYL) O-ETHYL ESTER
CAS Registry Number: 50782-69-9
Synonyms: Phosphonothioic Acid, Methyl-, S-(2-(Diisopropylamino)Ethyl)
O-Ethyl Ester; S-(2-Diisopropylaminoethyl) O-Ethyl Methylphosphonothiolate;
Ethyl-S-Diisopropylaminoethyl Methylthiophosphonate; Ethyl S-Dimethylamino-
ethyl Methylphosphonothiolate; VX
Chemical Formula: CnH26NO2PS
Molecular Weight: 267.37
SECTION I ~ REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LDIow dermal
(human) 0.086 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Liquid
Boiling Point: 568°F, 298°C (decomposes) (U.S. Army 1975, p. 3-5)
Specific Gravity (H2O=1): 1.0083 g/mL at 25°C (U.S. Army 1975,
P. 3-5)
Vapor Pressure (mmHg): 0.0007 at 25°C (U.S. Army 1975, p. 3-5)
Melting Point: Freezing point below -60°F, -51°C (U.S. Army 1975,
P. 3-5)
Vapor Density (AIR=1): 9.2 (U.S. Army 1975, p. 3-5)
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 50782-69-9
Page 2 of 3
PHOSPHONOTHIOIC ACID, METHYL-, S-(2-(BIS...
SECTION II (continued)
Appearance and Odor: Odorless liquid (Merck 1983, p. 1440) with an amber
color (U.S. Army 1975, p. 3-5)
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (U.S. Army 1975, p. 3-5)
Skin: Yes (Sax 1984, p. 1335)
Ingestion: Yes (U.S. Army 1975, p. 3-5)
Health Hazards (Acute, Delayed, and Chronic): Cholinesterase inhibitor
(Merck 1983, p. 1440). Lowest toxic oral dose (TDLO) to humans is 4 mg/kg;
lowest lethal skin dose to humans (LDLO) is 86 mg/kg (NIOSH/RTECS 1983, p.
124). Death within 15 minutes after fatal dose is absorbed (U.S. Army
1975, p. 3-5).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): 159°C (U.S. Army 1975, p. 3-5)
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Use protective clothing and respiratory
protection (U.S. Army 1975, p. 3-5)
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable:
Stable: Yes (U.S. Army 1975, p. 3-5)
Conditions to Avoid: Extreme heat (Sax 1984, p. 1335)
Incompatibility (Materials to Avoid): Not Found
-------
CAS Registry Number: 50782-69-9
Page 3 of 3
PHOSPHONOTHIOIC ACID, METHYL-, S-(2-(BIS...
SECTION V (continued)
Hazardous Decomposition or Byproducts: Highly toxic nitrogen oxides and
sulfur oxides (Sax 1984, p. 1335)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI - USE INFORMATION
Quick-acting military chemical nerve agent (U.S. Army 1975, p. 3-5).
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Decontaminants include bleach slurry and hot soapy water (U.S.
Army 1975, p. 3-5).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERG ONCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Exposure may produce red blood cell and
central nervous system effects (Sax 1984, p. 1335). Other symptoms include
difficulty in breathing, drooling, excessive sweating, nausea, vomiting,
cramps, involuntary defecation and urination, twitching, jerking,
staggering, headache, confusion, drowsiness, coma, convulsions, dimness of
vision and pinpoint pupils (U.S. Army 1975, p. 3-5).
Emergency and First Aid Procedures: Immediate decontamination of the
smallest drop is essential (U.S. Army 1975, p. 3-5).
COMMENTS
Sources searched, no information found:
DOT 1984
Hayes 1982
Hawley 1981
Weast 1979
-------
CAS Registry Number: 53558-25-1
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- PYRIMINIL
CAS Registry Number: 53558-25-1
Synonyms (NIOSH/RTECS 1983 Synonyms, Volume 3, p. 887): Urea,
l-Nitrophenyl-3-(3-Pyridylmethyl)-; DLP-87; DLP 787; N-(4-Nitrophenyl)-N'-(3-
Pyridinylmethyl)Urea; N-3-Pyridylmethyl-N'-p-Nitrophenylurea; Pyriminyl;
RH-787; VACOR; Urea, N-(4-Nitrophenyl)-N'-(3-Pyridinylmethyl)-
Chemical Formula: C13H12N4O3
Molecular Weight: 272.29
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 6.2 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): No
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Decomposes at 433°F, 223°C (Hayes 1982, p. 503)
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
Appearance and Odor: Yellow, resembling corn meal (Arena 1979, p. 174)
-------
CAS Registry Number: 53558-25-1
Page 2 of 4
PYRIMINIL
SECTION III - HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Yes (Arena 1979, p. 175)
Health Hazards (Acute, Delayed, and Chronic): This chemical may cause
death by cardiovascular collapse and respiratory failure (Arena 1979, p.
175). It may cause diabetes. Also it affects the central nervous system
(Hayes 1982, p. 504). Human survivors regularly develop an insulin-
deficient, ketosis-prone form of diabetes millitus (Gosselin 1984, p.
11-351).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: This compound is a solid pesticide (Buchel 1983,
p. 226). Small fires: dr> chemical, carbon dioxide, water spray, or foam.
Large fires: water spray, fog, or foam. Move container from fire area if
you can do so without risk. Fight fire from maximum distance. Dike fire
control water for later disposal; do not scatter the material (DOT 1984,
Guide 55).
Special Fire Fighting Procedures: This compound is a solid pesticide
(Buchel 1983, p. 226). Keep unnecessary people away; isolate hazard area
and deny entry. Stay upwind; keep out of low areas. Ventilate closed
spaces before entering them. Wear positive pressure breathing apparatus
and special protective clothing. Remove and isolate contaminated clothing
at the site (DOT 1984, Guide 55).
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
-------
CAS Registry Number: 53558-25-1
Page 3 of 4
PYRIMINIL
SECTION V (continued)
Conditions to Avoid: Not Fpund
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI ~ USE INFORMATION
Single-dose, acute rodenticide (Farm Chemicals Handbook 1984, p. C-238).
Not registered as a pesticide in the U.S. (USEPA/Pesticide Index 1985).
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
This compound is a solid pesticide (Buchel 1983, p. 226). Keep
unnecessary people away; isolate hazard area and deny entry. Stay upwind;
keep out of low areas. Ventilate closed spaces before entering them.
Remove and isolate contaminated clothing at the site. Do not touch spilled
material; stop leak if you can do so without risk. Use water spray to
reduce vapors. Small spills: absorb with sand or other noncombustible
absorbent material and place into containers for later disposal. Small dry
spills: with clean shovel place material into clean, dry container and
cover; move containers from spill area. Large spills: dike far ahead of
spill for later disposal (DOT 1984, Guide 55).
SECTION VIII - PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Symptoms include nausea, vomiting,
abdominal pains, chills, mental confusion, anorexia, aching, dilated
pupils, dehydration, chest pain, urinary retention, irregular heartbeat,
and muscular weakness (Arena 1979, p. 175). Exposure may also result in
visual disturbances, central nervous system depression and tremors
(Gosselin 1984, p. 11-351).
Emergency and First Aid Procedures: This compound is a solid pesticide
(Buchel 1983, p. 226). Move victim to fresh air; call emergency medical
-------
CAS Registry Number: 53558-25-1
Page 4 of 4
PYRIMINIL
SECTION IX (continued)
care. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact with material, immediately
flush skin or eyes with running water for at least 15 minutes. Speed in
removing material from skin is of extreme importance. Remove and isolate
contaminated clothing and shoes at the site. Keep victim quiet and
maintain normal body temperature. Effects may be delayed; keep victim
under observation (DOT 1984, Guide 55).
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Encyc Occupat Health and Safety 1983
Physicians' Desk Reference 1985
Oilman 1985
-------
CAS Registry Number: 58270r08-9
Page 1 of 3
EPA CHEMICAL PROFILE
Date: October 31, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- ZINC, DICHLORO(4,4-DIMETHYL-5((((METHYLAMINO)
CARBONYL)OXY)IMINO)PENTANENITRILE)-, (T-4)-
CAS Registry Number: 58270-08-9
Synonyms: Not Found
Chemical Formula: C9H15Cl2NsO2Zn (*NIOSH/RTECS 1985)
Molecular Weight: 334 (*NIOSH/RTECS 1985)
SECTION I -- REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LD50 oral
(rat) 9 mg/kg (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for notification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Zinc Compounds category
SECTION II -- PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found "
Appearance and Odor: Not Found
-------
CAS Registry Number: 58270-08-9
Page 2 of 3
ZINC, DICHLORO(4,4-DIMETHYL-5((((METHYLAMINO)...
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Not Found
Skin: Not Found
Ingestion: Not Found
Health Hazards (Acute, Delayed, and Chronic): Not Found
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: Not Found
NFPA Flammability Rating: Not Found
SECTION V -- REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: Not Found
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
-------
CAS Registry Number: 58270-08-9
Page 3 of 3
ZINC, DICHLORO(4,4-DIMETHYL-5((((METHYLAMINO)...
SECTION VI ~ USE INFORMATION
Not Found
SECTION VII -- PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Not Found
SECTION VIII ~ PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX - EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
Sax 1984
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 1980
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
NIOSH/RTECS 1983
-------
CAS Registry Number: 62207-76-5
Page 1 of 4
EPA CHEMICAL PROFILE
Date: October 9, 1985
Revision: November 30, 1987
CHEMICAL IDENTITY -- COBALT, ((2,2'-(l,2-ETHANEDIYLBIS
(NITRILOMETHYLIDYNE))BIS(6-FLUOROPHENOLATO))(2-)-N,N',O,O')-,
(SP-4-2)
CAS Registry Number: 62207-76-5
Synonyms: (NIOSH/RTECS 1983 Synonyms, Volume 1, p. 950) Cobalt (II),
N,N'-Ethylenebis(3-Fluorosalicylideneiminato)-; Cobalt,
Bis(3-Fluorosalicylaldehyde)Ethylenediimine-; N,N'-Ethylenebis(3-Fluorosali-
cylideneiminato)Cobalt II; Fluomine; Fluomine Dust
Chemical Formula: C16H12CoF2N2O2
Molecular Weight: 361.23
SECTION I - REGULATORY INFORMATION
CERCLA (SARA) 1986:
Toxicity Value Used for Listing Under Section 302: LC50 inhalation
(rat) 0.112 mg/liter/6 hours (*NIOSH/RTECS 1985)
TPQ: 100/10,000 (pounds)
RQ: 1 (pounds)
(statutory, for -otification under SARA Section 304(a)(2))
Section 313 Listed (Yes or No): In Cobalt Compounds category
SECTION II - PHYSICAL/CHEMICAL CHARACTERISTICS
Physical State: Solid
Boiling Point: Not Found
Specific Gravity (H2O=1): Not Found
Vapor Pressure (mmHg): Not Found
Melting Point: Not Found
Vapor Density (AIR=1): Not Found
Evaporation Rate (Butyl acetate=l): Not Found
Solubility in Water: Not Found
-------
CAS Registry Number: 62207-76-5
Page" 2 of 4
COBALT, ((2,2'-(l,2-ETHANEDIYLBIS...
SECTION II (continued)
Appearance and Odor: Not Found
SECTION III -- HEALTH HAZARD DATA
OSHA PEL: Not Found
ACGIH TLV: Not Found
IDLH: Not Found
Other Limits Recommended: Not Found
Routes of Entry: Inhalation: Yes (Sax 1984, p. 1339)
Skin: Not Found
Ingestion: Yes (Sax 1984, p. 1339)
Health Hazards (Acute, Delayed, and Chronic): This material is highly
toxic by oral ingestion or inhalation (Sax 1984, p. 1339).
Medical Conditions Generally Aggravated by Exposure: Not Found
SECTION IV -- FIRE AND EXPLOSION HAZARD DATA
Flash Point (Method Used): Not Found
Flammable Limits:
LEL: Not Found
UEL: Not Found
Extinguishing Methods: Not Found
Special Fire Fighting Procedures: Not Found
Unusual Fire and Explosion Hazards: When heated to decomposition, it
emits very toxic fumes of fluorine containing compounds and nitrogen oxides
(Sax 1984, p. 1339).
NFPA Flammability Rating: Not Found
SECTION V - REACTIVITY DATA
Stability: Unstable: Not Found
Stable: Not Found
Conditions to Avoid: Not Found
Incompatibility (Materials to Avoid): Not Found
Hazardous Decomposition or Byproducts: When heated to decomposition, it
emits very toxic fumes of fluorine containing compounds and nitrogen oxides
(Sax 1984, p. 1339).
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CAS Registry Number: 62207-76-5
Page 3 of 4
COBALT, ((2,2'-(l,2-ETHANEDIYLBIS...
SECTION V (continued)
Hazardous Polymerization: May Occur: Not Found
May Not Occur: Not Found
Conditions to Avoid: Not Found
SECTION VI -- USE INFORMATION
Not Found
SECTION VII - PRECAUTIONS FOR SAFE HANDLING AND USE
(Steps to be Taken in Case Material is Released or Spilled)
Avoid inhalation (see Section III above).
SECTION VIII -- PROTECTIVE EQUIPMENT FOR EMERGENCY SITUATIONS
For emergency situations, wear a positive pressure, pressure-demand,
full facepiece self-contained breathing apparatus (SCBA) or pressure-
demand supplied air respirator with escape SCBA and a fully-encapsulating,
chemical resistant suit. See the introductory information section at the
beginning of the profiles for additional information.
SECTION IX -- EMERGENCY TREATMENT INFORMATION
Signs and Symptoms of Exposure: Not Found
Emergency and First Aid Procedures: Not Found
COMMENTS:
Sources searched but no information found:
ACGIH 1983
NIOSH/OSHA 1978
Hawley 1981
Weast 1979
Merck 1983
DOT 1984
NFPA 1984
Student 1981
Weiss 1980
CHRIS 1978
Doull 19CO
Clayton and Clayton 1981-82
Arena 1979
Gosselin 1984
Encyc Occupat Health and Safety 1983
Buchel 1983
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CAS Registry Number: 62207-76-5 „
Page 4 of 4
COBALT, ((2,2'-(l,2-ETHANEDIYLBIS...
COMMENTS (continued)
••
Farm Chemicals Handbook 1984
Hayes 1982
Physicians' Desk Reference 1985
Oilman 1985
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