&EPA
  United States

                           Office of Research
                           and Development

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The  U.S. Environmental  Protection
Agency (EPA) relies on sound science
to safeguard both human health and
the environment. The Office of
Research and Development (ORD)  is
the scientific research arm of EPA.
ORD's leading-edge research helps provide the solid
underpinning of science and technology for the Agency.

ORD conducts research on ways to prevent pollution,
protect human health, and reduce risk. The work at
ORD laboratories, research centers, and offices across
the country helps improve the quality of air, water, soil,
and the way we use resources. Applied science at ORD
builds our understanding of how to protect and
enhance the relationship between humans and the
ecosystems of Earth.

               ORD  Mission
  •  Perform research and development to identify,
     understand, and solve current and future
     environmental problems.
  •  Provide responsive technical support to EPA's
     mission.
  •  Integrate the work of ORD's scientific partners
     (other agencies, nations, private sector
     organizations, and academia).
  •  Provide leadership in addressing emerging
     environmental issues and in advancing the
     science and technology of risk assessment and
     risk management.
As part of our mission, ORD has identified eight
research areas considered as highest priority. They are:
   Air
   Drinking Water
   Ecosystem Assessment and Restoration
   Global Change
   Human Health Protection
   Water Quality
   Pollution Prevention and New Technologies
   Endocrine Disrupting Chemicals (EDCs)
   For more information on these priority areas please visit
             www.epa.gov/osp/myp.htm

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Although much progress has been made in recent




years, air pollution continues to be a widespread



human health problem in the United States.




EPA's air quality program aims to ensure that the




air in every American community is safe and




healthy to breathe.
ORD's air research program provides the




scientific foundation for EPA's air quality




regulations for particulate matter, ground-level




ozone, carbon monoxide, sulfur




dioxide, nitrogen oxides, and lead.



In addition, ORD conducts




research to help understand and




manage the risks for these




compounds. We also do research




and assessments on hazardous air




pollutants that may be harmful to




people. As part of this work, ORD addresses the




potential effects of these compounds on susceptible



populations such as children, the elderly, and




people with respiratory illnesses. The air research




program includes clinical and laboratory studies,




epidemiologic studies, air quality model



development, characterization of emission sources,




and control technologies.

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Drinking  Water
 "he American public enjoys safe drinking water.




In the United States, utilities and other providers




select the best water sources, treat water to control




contaminants, and maintain sound water




distribution systems. Waterborne threats such as




typhoid fever and cholera have been virtually




eliminated. However, some public




health concerns remain from




pathogens and chemical
contaminants.
             des a strong
scientific foundation for EPA




decisions that help protect the public from
drinking water contamination. ORD's research
groundwater. These sources can be contaminated




with many different chemicals, including natural




substances such as arsenic and man-made
    3ounds nice pe
nermore, the
process of disinfecting water itself creates a




number of potentially toxic chemical byproducts.




This research is especially significant to infants,




children, and people with weakened immune




systems who are particularly sensitive to some




waterborne  contaminants.

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           i
Assessment
and  Restoration
Healthy ecosystems are a complex and delicate

balance of living things and their environment.

Robust, sustainable ecosystems can involve plants,

animals, people, soil, water, energy, and nutrients.

When this balance is disturbed by contaminants,

human activity, or invasive species, the ecosystem

is threatened.
ORD's ecosystem assessment and restoration

research program provides information to

understand the scale of a problem

within a threatened ecosystem,

need for action, causes of harm,

and success of mitigation and

restoration efforts.  We use

highly sophisticated computer

models to help interpret data on the

causes of ecological degradation. To quantify

the risks to ecosystems, ORD scientists develop

and use advanced risk assessment techniques. This

research helps to design cost-effective protection

and restoration strategies.

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Global  Change
Global change can have local impact.  Even




slight shifts in temperature, water currents,




forests, and atmospheric gases—whether the




result of human activity or natural trends—
can have far-rec
The U.S. Global ChanL




Research Program is an




integrated, multi-agency effort




that helps the world understand,




assess, predict, and respond to

global change.  ORD is one of more than



10 federal entities participating in this program.
The research program is assessment-oriented.
It focuses on th
ai conseque
climate variability and climate chanee on
human health, air quality, water quality, and




ecosystem health. ORD investigates the




influence of human activities in global climate




change, as well as adaptation options that can




build resilience to chanee.

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Environmental pollution poses potential risks to




the general public. Part of assessing those risks is to




address how they affect the most vulnerable groups




among us, such as children and communities that




rely heavily on subsistence fishing, hunting, and



farming.  ORD conducts human health risk




assessment research to assess and characterize more




accurately hazards to humans from exposure to




pollutants.








ORD leads research efforts to




ensure that pesticide residues




on food do not pose a health




hazard. Other areas of



research focus on how




chemicals and pesticides are




absorbed through the skin, ingested, or




inhaled.  A major component of this research is




understanding how these compounds travel




through air and water and cause potentially




harmful exposure to humans. The result of this




research is one piece of the puzzle that provides




scientifically defensible information for the




Agency's decision-making process.

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Water  Quali
                             ater resources is
vital to the ecology, human health, and the


economy. By investigating ways to clean up


contaminated waterways, sites, and groundwater,
ORD scientists are wo
the quality of our water resources.
                         and restore
Water quality
techniques used by the EPA's Office of Water to


protect the nation's freshwater and coastal
resources.
ORD's research assesses
damage to aquatic systems and


identifies sources of that dama—


The research also helps foreca:


the ecological, human health, and


economic outcomes of the possible
                                       '

solutions to water quality problems.


Because the sources of contamination are as


important as its effects, ORD also investigates


methods to clean up contaminated groundwater


and sediments.

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Pollution  Prevention
and  New
Technologies
EPA recognizes that pollution prevention, rather


than remediation, is the optimal solution to


environmental problems. ORD fosters innovative

design and production techniques to minimize or


eliminate industrial waste. This helps create

fundamental changes in the production and

delivery systems that move goods and services to


the American consumer and develops sustainable

approaches for using natural resources. ORD also

supports programs to develop new technologies to


clean up contaminated sites.




Working with industry, universities,


and other agencies, ORD tests

commercial-ready technologies

developed to prevent or solve


environmental problems. Examples

include nonpolluting metal finishing


processes, inexpensive ways to produce


polymers using less hazardous solvents, and

methods to remove chlorinated solvents from

contaminated groundwater. Cleaning up Superfund


sites using innovative technologies evaluated

under this strategy has saved billions of dollars.

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Endocrine  Disrupting
Chemicals  (EDCs)
in the last decade, the scientific community has

become increasingly concerned that humans and

wildlife are harmed bv exposure to chemicals that
interact with the endocrine (hormonal) system.

Chemicals that interfere with the body's natural

hormones are called endocrine disrupting

chemicals (EDCs). A broad range of

environmental contaminants, including some

pesticides and industrial chemicals, are either

known or suspected EDCs.
ORD scientists are developing

methods to detect the endocrine
disrupting a

and industrial chemicals. ORD is

developing computer-based tools

for predicting a chemical's endocrine

activity based on its molecular structure.
Using innovative research methods, investigators

are studying the magnitude of effects of, and

sources and levels of exposures to, EDCs in humans

and a variety of wildlife species. Engineers are
developing ap
or reducing e
EDCs from certain sources, such as sewage

treatment effluents and contaminated sediments.

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Future  Researc
Directions
Rapid developments in science and technology

present us with opportunities to develop innovative

solutions to environmental problems. Looking to the

future for trends that may harm human health and

the environment is critical to setting future research

directions. In ORD, foresight techniques are used to

plan research strategically by identifying potential

issues before they lead to environmental damage.
Nanotechnology, computational toxicology,

biotechnology, information technology,

and genomics are just a few of the

innovative areas of science that

EPA is exploring both for their

benefits and potential unintended

consequences.
                                           100 Jim
For example, ORD is working with its

scientific partners to examine the environmental

benefits of nano-based materials. Nanotechnology, the

science of designing materials at the molecular level,

offers environmental benefits that range from

designing cleaner manufacturing processes that

minimize waste and reduce pollutants to new methods

for detecting and cleaning up environmental hazards.

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Newport,
NHEERL
  Corvallis, OR
                                                  Narragans'
                                                  NHEERL
                                               Edison, NJ
                                               NRMRL
                  Ada, OK
                  NRMRL
                            Gulf Breeze, F>
                            NHEERL
Grosse Me, Ml
NHEERL
                                  Cincinnati, OH
            Research Triangle Park, NC
 Athens, GA >  NERL 4
 NERL        NHEERL
            NRMRL
            Chapel Hill, NC
            NHEERL
          .ARCH LABORA,
  AND CENTERS
  ORD is organized into three national laboratories, three
  national centers, and two offices located in 14 facilities
  around the country and in Washington, DC.  These labs,
  centers, and offices provide information and technical
  support to EPA program offices, regions, state/municipal/
  tribal governments, and other agencies performing
  environmental research, assessment, and risk management.
  ORD scientists also collaborate with private-sector partners
  to address important environmental issues.
  www.epa.gov/ord
          provides information to increase the accuracy of
  EPA's exposure and risk assessments for factors that stress the
  environment, including chemicals, living organisms,
  radiation, changes in land and water use, and changes in
  climate.  NERL also evaluates innovative technologies to
  improve  exposure assessment and provides information on
  stressor sources, pollutant transport and fate, and human
  exposure to pollutants.
  www.epa.gov/nerl
  The National Health and Environmental
                                                iPA's
  focal point for scientific research on the effects of
  contaminants and environmental stressors on human health
  and ecosystem integrity.  NHEERL's research is used by EPA
  and other government agencies to identify and understand
  the processes that affect our health and environment. The
  research helps to evaluate the risks that pollution poses to
  humans and ecosystems.
  www.epa.gov/nheerl
  The National Risk
                         conducts research on ways to
  prevent and reduce risks from pollution that threaten human
  health and the environment. NRMRL investigates methods
  to prevent and control pollution to air, land, and water, and
  to protect water quality in public water systems.
  NRMRL also assesses methods to clean up contaminated
  sites, sediments, and groundwater, prevent and control indoor
  air pollution, and restore ecosystems.
  www.epa.gov/ORD/NRMRL

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The National Center
                       is EPA's national resource center
for human health and ecological risk assessment. NCEA
develops new methods for risk assessment, and applies those
methods to the cutting-edge issues that the Agency faces.
NCEA functions as a critical link between researchers within
ORD and EPA decision makers. As a result, NCEA plays an
important role as a consultant  to EPA programs and regions
on the use  of science in environmental decision making.
www.epa.gov/ncea
The National Center for Enviro.
                    supports innovative environmental
research by scientists in the academic community. NCER's
Science to Achieve Results (STAR) program funds
competitive research grants and graduate fellowships in
numerous environmental science and engineering
disciplines to complement ORD's in-house research.
Through this same competitive process, NCER helps small
businesses address critical technology needs through its
Small Business Innovative Research (SBIR) program.
www.epa.gov/ncer
Center (NHSRC)
                    manages, coordinates, and supports
homeland security research and technical assistance efforts.
This research develops the scientific foundations to prevent
or manage threats. Efforts focus on developing methods to
clean up contaminated buildings (the Safe Building Program),
protecting the nation's drinking water supply (the Water
Protection Program), and improving risk assessment
techniques (the Rapid Risk Assessment Program).
www.epa.gov/ordnhsrc
                         two offices th<
  itical role in the
                                       They are the
Office of Science Policy (OSP) and the Office of Resources
Management Administration (ORMA). OSP is responsible
for science integration, coordination, and communication in
areas that include providing science support to EPA in the
regulatory decision-making process and management of
ORD's multi-year research planning. OSP also manages the
ORD Regional Science Program, staffs the EPA Science
Policy Council, and integrates tribal and environmental
justice issues into ORD's decision-making process.
www.epa.gov/osp

The Office of Resources Management Administration
(ORMA) ensures that ORD's laboratories and centers
have the resources necessary to conduct world-class
environmental research. ORMA provides management and
administrative  services and independently evaluates and
measures progress in meeting ORD's strategic goals. ORMA
also manages www.epa.gov/ord which is a useful portal
for finding information about ORD and its products and
research activities.

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                              ERA BOD/F-OartJOB
                                     May 2003

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