United states
                      Environmental Protection
                      Agency
                      Research and Development
  Office of Acid Deposition, Environmental
  Monitoring and Quality Assurance.
  Washington DC 20460
  EPA/600/S6-88/009a Sept.  1988
SEPA           Project  Summary

                      Incloqr  Air  Quality  in   Public
                      Buildings:  Vblume  I
                      L S. Sheldon, R W. Handy, T. D. Hartwell, R. W. Whitmore, H. S. Zelon, and
                      E. D. Rellizzari
                       This report documents the first of two
                     studies  of indoor air quality in public
                     buildings carried  out by the U.S. En-
                     vironmental  Protection  Agency in  re-
                     sponse to public and Congressional con-
                     cern. A total of 10 buildings were studied
                     in the program. A  report on the last six
                     buildings studied (Sheldon 1988) is be-
                     ing published simultaneously with this
                     report, which deals with the first four
                     buildings investigated.
                       This Project Summary was developed by
                     ERAS  Office of Acid Deposition,  En-
                     vironmental  Monitoring and  Quality
                     Assurance, Washington, DC, to announce
                     key findings of the research project that
                     is fully documented in a separata report
                     of the same title.  (See  Project Report
                     ordering information at back),


                     Introduction
                       In 1982. Congress mandated that the US.
                     Environmental Protection Agency (EPA) carry
                     out a study of indoor air quality. Because very
                     little was known at that time about volatile
                     organic chemicals (VOCs) in indoor air, it was
                    .decided to concentrate  the study-on this,
                     class of  compounds, which includes a
                     number of  carcinogenic' and  mutagenic
                     species (benzene, tetrachloroelhylene, eta).
                     These compounds were being  extensively
                     studied in private homes in EPA's ongoing
                     Total Exposure Assessment  Methodology
                     (TEAM) Study (Wallace 1987); therefore it was
                     decided to concentrate on buildings rather
                     than homes. Buildings where people spend
                     tang periods of time were selected for study:
                     schools, homes for the elderly, and office
                     buildings. These  buildings also contain
                     populations (children, the elderly) that may
                     be more sensitive to air pollutants.
  Study Design

   The goals of the study were the following:

   1) Identify  all  VOCs  collected by  the
      available methodology (Tenax absor-
      bent, GC-MS detection) on a subset of
      samples, both outdoor and indoor.

   2) Quantify a set of target VOCs'. selected
      on the basis of their potential health ef-
      fects, production volume, and amenabi-
      lity  to  collection  on Tenax,  in  all '
      samples.

   3) Determine the effect of aging on the
     concentrations of VOCs within a newly
     constructed building.

   4) Measure emissions, of  VOCs  from
     building materials and processes.

   5) Measure concentrations of inhalable
     particles, including metals, and air ex-
     change rates in all buildings.

   Four buildings were selected for study: two
 homes for the elderly in Washington, DC; an
 elementary school in Washington DC; and
 an office building scheduled to  be con-
 structed in Research Triangle Park, NC. The
 first three buildings were monitored once on-
 ly, but the new office building was monitored
 three times: immediately following comple-
 tion of construction; two months later (after
 the occupants moved in); and again five
 months after completion of construction.
 ' Each monitoring visit lasted, two or three
 days. From three to five indoor sites were
 selected and one outdoor site (near the air
 intake for-the building) was monitored over
 consecutive 12-hour periods. Air exchange
 rates  were determined for each  12-hour
period by injecting sulfur hexafluoride (SF$)
                                                                       Printed on Recycled Paper

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  Snto  the building  ventilation  system and
  measuring tha decay in concentration.
 aged 102% for all chemicals. Precision of du-
 plicate samples averaged ± 25% (Table 1).
...: Measurement Methods '    ' ' ....... ' "
    Mflasurenjent methods are described ful-
  ly Jn  the  report.  Following  i  .a  brief
  Description. ...............
    1) \tofatileorganics. Mr samples were col-
  tected in cartridges containing 15 g of 35/60
  mesh Tenax™. 20 Nters of air were sampled
  oyer each 12-hour period. Thermal desorp-
  ' lion" was followed by GC-MS analysis.
    2) Panicles. Inhalabte particles including
  both the fine (<2£^) and coarse (25-10/0
  fractions  were collected  on dichotomous
  samplers (using  virtual impactton) and on
  sampJars designed for EPA by the National
  Bureau of Standards (using stack fitters). The
  fitters were weighed by microbalance and
  analyzed for metajs by proton-induced x-ray
  ^mission (PIXE),
    Near-real-time particle measurements us-
  ing the Ptezobalance"' were made at some
  buildings to document short-term variations
  fn particles  caused by sources  such as
  smoking,
    3) Emissions from materials.  Headspace
  vapors  from heated materials in belljars were
  coltected on Tenax cartridges arid analyzed
  by GC-MS for the target compounds. Several
  materials  (paints,  wallpaper,   carpet,
  adhesives) were then selected for analysis of
:j emissions in a room-size chamber (Pierce
" Foundation, Yale Univ.}. Materials were aged
  for one week, placed in the chamber and
  allowed to equilibrate for 24 hours, and their
  organic emissions were then collected on
  triplicate Tenax cartridges and analyzed by
  GC-MS. One chamber experiment used
  cleaning materials and an insecticide col-
  lected from the supplies in the office building.
  A technician applied detergent,  chlorine
  bleach scouring powder, and the spray insec-
  ticide at Intervals during the sampling period
  in the chamber.
  Quality Assurance
    Three blank Tenax cartridges from each
  Tenax batch employed in the six monitoring
  visits were analyzed for the target pollutants.
  Three additional cartridges were spiked with
  known amounts of the target compounds and
  carried  to the field and returned unexposed;
  these wert  then analyzed to determine
  recovery efficiencies. Deulerated compounds
  were toaded oh some cartridges as a further
  check on recovery efficiency. Ten percent of
  exposed  cartridges were  collected in
  duplicate to determine sampling precision.

  Results
  Quality Assurance
  Blank levels were low for all chemicals except
  benzene. Median recovery efficiencies aver-
 Qualitative Identifications
 A total of 16 samples (12 indoor, 4 outdoor)
 were analyzed to identify a broad spectrum
 of VOCs occurring in the four buildings. More
 than 500 chemicals were identified. Those
 appearing  most often include- aliphatic,
 aromatic, and chlorinated compounds (Table
 2).
  A typical air sample contained 100-200
 compounds. Of these, about 50 compounds
 per sample were unique to that sample. In-
 door samples were normally more complex
 than outdoor samples.

 Quantitative Results
 A total of 165 Tenax samples were collected.
 All four buildings had higher concentrations
 of VOCs indoors than outdoors. For the three
 older buildings, the indoor-outdoor ratio of
 total organics was about 2 or 3 to 1. However,
 this ratio was nearly 50 to 1 for the new of-
 fice building immediately following construc-
 tion. After two months, this ratio dropped to
 about 10 to 1 and after an additional  three
 months, the ratio was about 5 to 1. Chemicals
 at elevated levels in the  new building includ-
 ed aromatic compounds such as xylenes and
 ethylbenzene, and aliphatic compounds such
 as decane and undecane (Table 3).
  Emissions from 16 materials collected from
 the new office building were measured on a
semiquantitative basis  using  headspace
analysis.  Between  13  and  111  organic
chemicals were identified from each material.
Common emissions included xylenes, ethyl-
benzene, decane and undecane, and 1,1,1-
trichloroethane. All but one of the 15 target
chemicals were emitted by one or more of
the  materials.  (The   one exception  was
tetrachioroethytene.)
  Emission  rates  determined  from  the
chamber studies are  displayed in Table 4.
The mixture of cleaning  agents  (liquid
detergent  and a chlorine bleach scouring
powder) and a spray pesticide produced
large quantities of chlorinated compounds,
whereas the paint, carpet, and  adhesives
produced  primarily aromatic and aliphatic
compounds.
  Fine particle mass averaged over 24-hour
periods ranged from 30-100 fig/m* in smok-
ing areas, compared to 10/ig/m3 in nonsmok-
ing areas, (Table 5).  Short-term measure-
ments using  the  Piezobalance™ docu-
mented much higher concentrations (nearly
300 uglm3) during.smoking episodes in a
smoking lounge (Figure 1).
  Air exchange measurements showed
typical ranges of 05 to 1 air change per hour
for two buildings (Table 6). One building, a
home for the elderly, had consistently- high
air  exchange rates due to  high negative
pressures created by excessive heating and
very cold winter temperatures.
Table 1:
Chemical
Recoveries. Blank Levels, and Precision for Target Volatile Organics
Blank
Recoveries" Levels'
(%Jl (ng/cartridge)

Median
RSD"
(%)
Chlorinated
Chloroform
1,2-Dichhroethane
1.1,1-Trichloroethane
Trichloroethylene
Tetrachioroethytene
p-Dichlorobenzene
Carbon Tetrachtoride

Aromatic
Benzene
Styrene
Ethylbenzene
o-Xytene
m+p-Xyfene

Aliphatic
Decane"
Undecane
Dodecane

Mean for all Chemicals
     96
    102
    104
     99
     95
    109
     97
     80
    109
    111
    104
    104
    120
    105
    98

  102 ± 9
   5
  NDF
  12
   2
  ND
   2
  ND
  36
   6
   2
   1
   4
  ND
•   4
   2

5±  9
  37
   7
  31
  20
  16
  20
  23
  35
  40
  23
  25
  25
  30
  22
  22

25 ± 8
'Median of JB triplicate determinations.
"Relative standard deviation (N-17 duplicates)
cNot detected.

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 Tabto 2:    Most Cdmmon Organic Compounds at Four Buildings

 Class/Compound                      n*
                                     A/6
Aromatic Hydrocarbons
benzene
toluene
xylenes
styrene •
ethylbenzene
ethyl methyl benzenes
trimethyl benzenes .
dimethylethylbenzenes •
naphthalene
methyl naphthalenes '
propylmethylbenzenes,.
n-propyl benzene ~-
diethyl benzenes '

Halogenated Hydrobarbons
Tetrachloroethylene
7, 7, 1-trichloroethane
trichloroethylene
dichlorobenzenes
trichlorofluoromethane '
dichloromethane
chloroform , , . .

Esters
ethyl, acetate '' •.
m-hexyl butanoate
'Alcohols
.2-ethyl-1-hexanol
n-hexanol
.- 2-butyloctanbl
n-dbdecanol
•Aldehydes
n-nonanal
n-devansil .
Miscellaneous - '
acetone '
acetic acid . •
dimethylphenbls
ethylene oxide .

76
16
76
76
76
76
/6
75
75
75
14
13
12
.,

i 76
75
14
12
12
11
10


•-''.' ' 'a"
.4

9
8
7-
'•• ' 6'

73
, 70

16
10
-. 6
4
Aliphatics '•"- •
undecane
'_ 2-methylhexane
*2-methylpentane
'- 3-methylhexane •?..'•
3-methylpentane
octane, " • , • - • . .
nonane , \
decane '
-dodecane
tndecane
- methylcyclohexane .-••••••
' ' • heptane .
• tetradecane . .
2-methylheptane • •
cyclohexane .•
• pentadecarie
••- 4-methyldecane
2,44imethylhexane
pentane
hexane
eicosane
3-methylnonane -
1,3*timethyl- . :
cyctopentane














-! '

70
1 -.9-
9
9
' •- 9
9
• g
9
• • •'-. 9
9
9
. 8
- . '•• 8
- '8
8
7
7
7
6
6
6
6
•. /
.'-. 6















 "Number of samples (of 16) with compound present.
 "Number ol samples (of 10) with compounl present.
 Discussion
   Of the 500 chemicals identified in the four.
 buildings, about half were found only once,
 suggesting  the presence  of many  small
 sources rather than a few dominant ones.
 Aliphatic  hydrocarbons formed the most
.populous  category  of  chemicals,  with
 aromatic  hydrocarbons  and   chlorinated
 hydrocarbons  forming  the  next  most
 populous  categories. Alcohols,  acids.
 ketones, aldehydes,'and esters were also
 prevalent. It should  be noted that the ob-
 served  chemicals did not  include organics
 more volatile than hexane or less volatile than
 dodecane. Moreover, most polar compounds
 were also not collected by the methodology
employed. Thus the observed VOCs were
only a portion of the total VOCs present.
  As observed in the TEAM Study of in-
dividual homes (Wallace, 1987a), indoor con-
centrations of VOCs in buildings exceed out-
door concentrations for all of the prevalent
target chemicals. The TEAM Study findings
implied that the source of the higher indoor
concentrations  might be  emissions  from
building materials, consumer products, or in-
door processes such as cleaning or smok-
ing. The present study documents that the
19 materials and several processes studied
emit essentially all of the  observed target
chemicals. The question of what proportion
of the observed concentrations might be at-
 tributed to the materials, and processes tested
 has been treated more fully in Wallace, 1985.
 That paper concludes that many of the target
 chemicals are emitted by a very large num-
 ber of materials and processes,:and'that
 .therefore the observed concentrations may
 often be due to small contributions from
 many sources. These findings are in good
' agreement with  the later more  extensive
 studies of 31 building materials carried out
 in the EPA companion,study of six buildings
 (Sheldon, 1987; Wallace, 1987b; Jungers, 1987,)
   The new office building had concentrations
 of five aromatic and aliphatic hydrocarbons
 that were two orders of magnitude greater
 than the concentrations observed 5 months
 later. Half-lives of the five chemicals ranged
 from 2-8 weeks (Pellizzari, 1984; Wallace ef
 a/.,  1987). Thus  the time required for this
 building to approach the outdoor concentra-
 tions would range from 3-12 months. This fin-
 ding supports the Scandinavian decision to
 require 100% outdoor air as makeup air for
 the first 6 months of a new building's life.
   Fine panicle mass was strongly affected
 by smoking.  Levels in smoking lounges and
 apartments ranged from 20-90 ^g/m3 greater
 than in nonsmoking areas. One apartmert.
 with with two heavy smokers had 24-hour-
 average levels of  up to 100 ^g/m3. These fin-
 dings are similar to  those in the extensive
 series of studies carried out by Spengler and
 coworkers in -the   Harvard  6-City  Study
 
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T*«t 3: VolttHe Orgatfcs in a Now Office Building'
Concentration (ng/m*)
WV--4.., Indoors1 Outdoors*
*ct»mic*i July Sepf. Dec a//7nps
. AJiphwics
£•*">• 3ao 38 ^ ' 2
"J^» . 770 48 73 . 1 •
DodK*» 47 19 5 02
Aromtlics . .
m+p-Xyfcn* 740 79 's 2
o-Xyiute 74 e 4 j
£ttyi>*ur*>» w 6 , J
•f«w» 5 7 7 3
SrynKW a 7 4 ,
Httoearbora
i,1,1'Tricahmttham 3SO 700 49 e
T«ertcWoro»Ojyteo» .7 2 3 r
TWeAtoroathytoo* * 7 38 27 03
Cartwj r«6*tf*vfcte j 7 7 ,
CMorofofffl 1 ' 2 78 6
MXchtofobanzene 7 7 1 ND
Total of 14 Optwcs , 7300 326 750 25~
•«•**! of «x JS-ftow *wa9»s *f ffv» tabor fcc*tion.s.
**<*»» o< /8 72-ftx/r «v»/ip« M am outdoor locttion.
T«W» 4.- Emission Rates From Various Selected Sources
Emission Rate (ng/min/m>)
_. . , Cleaning Agents Painted Glued Glued
JXHHnical and Insecticides Sheetrock Wallpaper Carpet
CnKfOform 1S,000±2SO (1.5)* ND" ND ND
I'ffSSf?"'"^* 12'°°° ND 310±46 (15) 180+12 (7)
1,1.1-Tnchhmethane 37.000 ±15.000 (42) 31±15 (47) 84±48 (57) 260+31 (12)
BtmOM ND 120±29 (25) ND ND
Ctrixm Tttrachtoride 71,000±5.300 (7.5) ND ND ND
7/fchtoro«%to/» 370±47 (3.8) ND ND ND
TttrtcnlorotthytenB ND ND ND ND
Cktorobomtn* ND ' ND ND ND
Ethytoetuene ND ND ND 77+39 (50)
P^W ND ND 26±6.5 (25) 1SO±24 (16)
®y?* ND • ND ND 98±14 (15)
*?? ND ND 6.5±3.1 (50) 98+26 (27) ,
m-DKMorobonzerm 560±20 (3.6) ND ND ND
O^ichhfoberaene 440±S (1.2) ND ND 41 ±14 (36)
rvOtca/w 770±27 (16) 240±29 (12) 190±77 (40) 545 ±150 (28)
oJXchforobemera ND ND ND ND'
n^nctoca'» r.700±0 (0) 1500±3SO(24) 300 ±110 (36) 500 ±150 (30)
•Cotttic»nt ot vintiK* (to). N . 3 observitions. ±SD (CV). N - 3 oteervatois.
*ND m not cfcftcwd (vOots mn in no/mm/my,
T«W« S.' Rtspirable Particles at Two Homes for the Elderly
Loc*'*™ Concentration (vglm^f
Home #2 Home#1 ,
Smoker's Apartment • .89 39
Commons Area 76* 30c
Nonsmoktf's Apartment g g
Outdoors ' 4" 10
•MMO of then con&cutivt 24J>our umptes.
*Sotn» smohng obnrvtd
^ptc*«tf tmotung lounge
Ont U-rxwr stmph
considerably greater for these chemicals in
indoor air than in outdoor air or, (except for
chloroform), in drinking water. The risks
associated, with the type of buildings studied
here would be smaller by the ratio of the time
spent in them to the time spent in homes.
The second type of health effect is acute,
consisting of eye, nose and throat irritation,
headaches, neurotoxic symptoms such as
depression, irritability, and forgetfulness, and
general malaise— a group of symptoms often
described as "Sick Building Syndrome"
(SBS). Although the cause or causes of SBS
are unknown, several hypotheses implicate
tow-level concentrations of VOCs as a possi-
ble cause (Berglund, 1982; Molhave, 1984).
The economic effect of SBS may be con-
siderable, if a large proportion of workplaces
.are affected. One nationwide survey has
reported that 25% of American workers feel
the quality of air at their workplace affects
their work adversely. If so, economic produc-
tivity may be lowered by a significant amount.
Conclusions
At least 500 volatile organic compounds
have been identified in indoor air in four
buildings. These indoor air samples contain-
ed from 100 to 200 VOCs, often at levels that
were several times the outdoor concentration.
The sources of these elevated indoor air "con-
centrations included building materials, con-
sumer products, and processes such as
cleaning and smoking. The materials tested
emitted between 18 and 111 VOCs at rates
ranging up to 1000 ^g/m2/h.
Concentrations of individual aromatic and
aliphatic compounds such as xyienes and
decane were elevated over outdoor levels by
factors of 100 in the new building studied.
Half-lives of these compounds ranged from
2-8 weeks. The time to reach concentrations
comparable with outdoor levels was
estimated at 3-12 months.
Concentrations of fine-particulates were
elevated by 20-70 uglrrfl in smoking areas.
Recommendations
This study has indicated that concentra-
tions of certain target VOCs are elevated in
buildings due to emissions from certain
building materials. Only four buildings were
monitored and only 16 building materials
were tested for emissions. Considering that
the building stock in the U.S. is more than
3 million, and that building materials and con-
sumer products probably number in the hun-
dreds of thousands, it is clear that only the
surface has been scratched in this study.
Many more buildings of various types
(hospitals, enclosed shopping malls, etc.)
where people spend a considerable fraction "
of their time should be monitored before it
will be possible to estimate the frequency

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   Figure 1.    Respirable particulales in smoking lounge of the elderly home « ; (3/24/83).:
         360
        320
        280
      .  240
   I
  •I-
       200
        160
       120-
        80.
        40-
                                                                       Nine Smokers
                                        Three Smokers
No Smokers
  Present
                             :1
                                                   Mean Concentration
                                                   in nonsmoking area
         5:00 PM
                             5:30
                                               6:00
                                                                  6:30
                                         Time
 distribution of VOC concentrations in such
 buildings.  Many more building  materials
 should be tested to determine their rates of
 emission of chemicals of concern-before a
 trustworthy estimate of the range.of emission
 rates can be.achieved.
 Table 6:    Air Exchange Rates at Three
           Buildings
Building
Elderly Home #7
School
Office (July)
Office (September)
Air Exchange Rate*
(ach)
1.72 ± 0.41
0.85 ± 0.31
0.61 ± 0.32
0.52. ± 0.25
'Mean of 4-6 measurements over consecutive 12-4mur
 periods at each ol 3-4 indoor fccMbns in each txOOing.
                              An economic study of the effects of indoor
                            air quality on productivity would help to clarify
                            the magnitude of the indoor air quality pro-
                            blem  in   the  office  and  workplace
                            environment.

                            References
                              Berglund, a, Berglund, U, UndvaK.T. and
                            Nicander-Bredberg, H. (1982), "Olfactory and
                            Chemical Characterization of  Indoor Air—
                            Towards a  Psychophysical Model  for Air
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                             Jungers.  R. H. and Sheldon, L.S. (1987)
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     A/lolhave, L., Bach, B. and Pederson, O.F.
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  ,   Pellizzari, E.D., Sheldon, L. S., Sparacino,
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     Repace, J. L. and Lowrey, A.  H. (1980) "In-
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-------
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Smoking,  Gas Cooking, and Respiratory
Health of Children Living in Six Cities" Amer.
Rev. Respir. Dis. 129:366-374.
  L S. Sheldon, R. W. Handy. T. D. Hartwell. R. W. Whitmore. H. S. Zelon. and
     £, D. Pellizzari are with Research Triangle Institute, Research Triangle Park,
     NC 27709.
  Lance Wallace is the EPA Project Officer (see below}.
  The complete report, entitled "Indqpr Air Quality in Public Buildings: Volume
     I." (Order No. PB 89-102 503/AS; Cost: $44.95.  subject to change) will be
     available only from:
          National Technical Information Service
          B28S Port Royal Road
          Springfield, VA 22161
          Telephone: 703-487-4650
  The EPA Project Officer can be contacted at:
          Office of  Acid Deposition,  Environmental Monitoring and Quality
          Assurance
          U.S. Environmental Protection Agency
          Washington. DC 20460

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