542F04010
                  Development of Analytical  Methods  for
                  Fuel Oxygenates	
                         Through the Measurement and Monitoring Technologies for the 21st Century (21M2) initiative,
                         EPA's Office of Solid Waste and Emergency Response (OSWER) is identifying and supporting
                         deployment of promising measurement and monitoring technologies by matching existing and
                         emerging technologies with OSWER program and client needs in the fields of waste management
                         and site cleanup. OSWER has identified a number of "needs areas" as the focus of 21M2. These
                         needs reflect evolving requirements across all waste programs. A recent list and description of
                         needs is available at the 21M2 Internet site at httD://www.cluin.ore/Drograms/21m2/needs.cftn.
Background

EPA developed this fact sheet to summarize a recent
study funded in part by the 21 M2 program on the
analytical methods used for fuel oxygenates. The
study produced optimized protocols to preserve and
analyze groundwater samples for the suite of fuel
oxygenates commonly found at petroleum fuel release
sites. The most common of these oxygenates are
methyl tertiary-butyl ether (MTBE) and ethanol.
Other oxygenates include tertiary-amyl methyl ether
(TAME), ethyl tertiary-butyl ether (ETBE),
diisopropyl ether (DIPE), tertiary-amyl ethyl ether
(TAEE), tertiary-butyl alcohol (TBA), tertiary-amyl
alcohol (TAA), and methanol. More comprehensive
information on the topic and the waste program fact
sheet on the method are available from the Office of
Underground Storage Tanks (see "Project
Information").

Project Objectives

EPA evaluated the performance of modifications to
existing SW-8461 methods that are relevant to the
1 SW-846 is EPA's official compendium of analytical and
test methods that have been "evaluated and found to be
among those acceptable for testing under Subtitle C of the
Resource Conservation and Recovery Act (RCRA), as
amended."  SW-846 is a guidance document that sets forth
acceptable, although not required, methods. Under the
Agency's Performance-Based Measurement System
approach as applied to waste sites, any method may be used
provided it can be demonstrated to detect the analyte(s) of
concern in the matrix of concern at the regulatory level of
concern.
analysis of MTBE and other oxygenates. Study
objectives were to:

    identify the most feasible and cost-effective
    analytical methods and optimum operating
    conditions to analyze fuel oxygenates in water
    with a target sensitivity of 5 u-g/L;
•   collect information on performance of alternative
    analytical methodologies;
•   evaluate sample preservation techniques and their
    influence on sample  integrity;
    disseminate the data from this study through
    guidance documents; and
    Recommend potential modifications to existing
    SW-846 methods.

Project Results

Evaluation of Purge-and-Trap Followed by
GC/MS.  One phase of the study involved evaluating
purge-and-trap (Method 5030B) and gas chromato-
graphy/mass spectrometry (GC/MS, Method 8260B)
on MTBE, TBA, DIPE, ETBE, TAME, and TAEE.
The results of this phase  demonstrated that the most
consistent oxygenate recoveries are obtained when
samples are prepared using Method 5030B with a
heated (80° C) purge-and-trap and then subjected to a
determinative analysis using Method 8260B with a
DB-Wax capillary column. A RTX-Volatile capillary
column with a heated purge did not significantly
improve the overall method performance compared to
the performance using the DB-Wax capillary column.
In addition, BTEX interferences did not adversely
affect the chromatographic separation, quantitation,
and recovery of the oxygenates. If ethers are the only
target oxygenates of concern, then the sample  need not
be heated to obtain 5  u.g/L detection limits.
                                                                                           SAt-2.

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                                                                          Office of Superfund Remediation
                                                                                and Technology Innovation
                                                                                         EPA/542/F-04/010
 Use of Static Headspace and Trisodium
 Phosphate Preservative.  A second phase of the
 study involved the use of static headspace (Method
 5021) to prepare samples collected from two oxygen-
 ated fuel release sites. Three different laboratories
 analyzed the split samples from each site. Also tested
 in this phase of the study was the ability of trisodium
 phosphate, a sample preservative (used instead of
 acid), to prevent acid-catalyzed hydrolysis of the
 ethers during analysis at elevated temperature.  All
 samples exhibited good agreement between analyses
 of MTBE, TAME, ETBE,  and TBA (where present).

 Refrigeration and chemical preservation, the key
 components of sample preservation, are used to
 prevent deterioration and degradation of groundwater
 samples. Refrigeration effectively inhibits the
 chemical deterioration of the sample, and chemical
 preservation is necessary to prevent biodegradation.
 Most protocols for the chemical preservation of
 groundwater samples call for the addition of a suffi-
 cient volume of hydrochloric acid to adjust the pH of
 the sample to less than 2. However, under the high
 temperature conditions of GC analysis, ethers undergo
 acid-catalyzed hydrolysis inside the instrument.  This
 consumes ether and creates alcohol, giving false
 results.  Consequently, another objective of EPA's
 investigation was to determine whether this effect was
 significant under expected  operating conditions for
 oxygenate analysis and if so, to evaluate an
 alternative.  The study evaluated two sets of acidified
 samples using heated purge-and-trap and GC/MS
 analysis.  For samples with a pH of 1 and 30 minutes
 of incubation, more than  50 percent of the MTBE in
 the sample was converted to TBA during passage
 through the GC instrument.

 The study found that ether hydrolysis can be avoided
 by using a base rather than  an acid as the chemical
 preservative. However, the pH of the preserved
 sample must exceed 11 to be effective.  This alkaline
 condition prevents the biodegradation of organic
 compounds in the sample while avoiding potential
 problems of acid-catalyzed  ether hydrolysis.  It also
 eliminates the problem of effervescence in samples
 with high carbonate alkalinity that is caused by acid
preservation.

To achieve the elevated pH, approximately 0.4 grams
of trisodium  phosphate dodecahydrate ("TSP") is
recommended.  The TSP is added to the sample vial
prior to sample collection. To avoid the need for a
scale in the field, the sample team in this project used
 a pre-sized scoop that held a volume of TSP whose
 weight is equivalent to 0.4 grams. Following the addi-
 tion of the TSP, each vial was filled with groundwater
 and sealed without headspace (the same as is done for
 a sample preserved with acid). If purge-and-trap
 (Method 5030B) is used to prepare the water samples,
 it is particularly important and good laboratory
 practice to prevent transfer of aerosols from the
 purged water to the trap and GC column.

 Project Information

 A more detailed summary of the EPA study on the
 analytical methods of fuel  oxygenates is available in
 Analytical Methods for Fuel Oxygenates, L.U.S.T.: A
 Report on Federal & State Programs to Control
 Leaking Underground Storage Tanks, New England
 Interstate Water Pollution Control Commission,
 Bulletin 42, October 2002.
 httv://w\vw.eDa.ffov/swen4stl/mtbe/LL42Anatvtical.Ddf

 The Office of Underground Storage Tanks has
 prepared a fact sheet on "Analytical Methodologies
 for Fuel Oxygenates," EPA 510-F-03-001.  It is
 available at:
 http://www. eva. sov/oust/mtbe/omethods. pdf

 For more information on this study, contact Barry
 Lesnik, U.S. EPA Office of Solid Waste, 703-308-
 0476, lesnik.barrv@eDa.gov.

 Additional Information

 More information can be found at the following
 locations:

 •   Analytical methods.
    EPA's Methods Information Communication
    Exchange (MICE) hotline  at 703-676-4690, or
    visit the MICE website at
    http;//www. epa. zov/SW-846/mice. htm

•   SW-846 methods.
    httt>://www. epq. eov/epaoswer/hazwaste/test/rnam.
    htm
   EPA's Office of Underground Storage Tanks.
   htto://www. epa. sov/oust

   21M2 program.
   http://cluin.orff/Drofframs/2Jm2/

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