VvEPA
EPA's Indoor Air Quality Research Update
Office of Research and Development
               Inside   I A Q     }
                                                               EPA/60Q/N-93-021
                                                                Fall/Winter 1993
In  This Issue
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The  second material  tested was  polyvinyl  chloride flooring
material. The laboratories were asked to determine the emission
rate  for four compounds (phenol, 1,2,4-trimethylbenzene,  n-
decane,  and  n-undecane)   and  for  total  volatile  organic
compounds (TVOCs) at 48 and 72 hours.

Water-based  floor wax was the third material  tested.  The
participants  were  requested to use  an average  wax  layer
thickness of 0.05 mm. Sampling was carried out at 10 different
times in order to determine the concentration/time curve for four
compounds (oc-pinene, linalool, geraniol, and a-cedrene) and for
TVOCs.

No method was prescribed for VOC sampling and analysis, and
each investigator was free to use his/her  usual  procedure.
However, it was requested that TVOC  concentrations  be
reported as toluene equivalents.

Results from the  20  participating  laboratories showed that
chambers of different materials (5 glass and  18 stainless steel)
and of widely different capacities (0.035 to 1475L) appeared
equally suitable. The repeatability of duplicate measurements
(including sampling) within each laboratory was good.

The analysis  for n-dodecane showed, for most laboratories,  an
unexpected and yet unexplained discrepancies.  Hypotheses which
might  explain these discrepancies include irreversible or very
slowly reversible sinks in the chambers, error in the flowrate
determination, error in the analytical system, error in weight loss
measurement, and inadequate chamber mixing.

The interlaboratory agreement appeared  reasonable (coefficient
of variation 26 - 42%) with the tile, but the scatter was very
high for the wax. At least three kinds of difficulties seem to have
occurred with the wax test: 1) chamber  difficulties such  as
chamber sink effects or highly scattered data; 2) analytical
difficulties; and 3) curve fitting difficulties. (EPA Contact: Bruce
A. Tichenor, AEERL, 919-541-2991)
Source Characterization Research
Methods for Characterization of Biocontaminant Sources

AEERL  and Research Triangle Institute are developing two
methods  for evaluating indoor biocontaminant sources. The first
method uses static chambers (32 x 39 x 51 cm) and saturated salt
solutions. This method can be used to assess the ability of indoor
materials to support the growth of microbials  such as fungi,
bacteria,   and  dust mites. Both  qualitative and quantitative
analyses  are used  to  characterize the microbial growth. Four
types of ceiling tiles  and two duct lining materials  have been
tested in these static chambers to validate the methodology. A
standard  guide  for the static chamber test method is currently
under review by the American Society of Testing and Materials
(ASTM)  Subcommittee D22.05.06.
The second method for evaluating biocontaminant sources uses
a dynamic chamber (2.44 x 2.44 x 2.44 m). Continuous air flow
through the chamber is provided to simulate a typical room, and
the air mixing pattern in the chamber is controlled by a ceili
fan. Aerolized spores can be injected into the chamber, and
growth of biocontaminants on various sources can be monitored
through observation windows. The chamber can also be used to
evaluate in-room air cleaners  (EPA Contact: John C.S. Chang,
AEERL, 919-541-3747)
Exposure Ane»»ment Research
Development of Gene Probes for Identification of Fungi

Current methods for  identifying  fungi in  air samples are
dependent on culturing the organisms, followed by detailed
morphological examinations, both of which are time consuming
and difficult methods. As a result, EMSL is researching the
feasibility of developing molecular-based detection methods using
polymerase chain reaction (PCR) amplification of small subunit
ribosomal RNA genes. These genes were chosen because: they
are present  in  all organisms;  they contain highly  conserved
sequence regions which can serve as priming sites for PCR
amplification; and they contain variable sequence regions which
can serve as target sites for genus or  species specific DNA
probes.

The first phase of this project is to establish a data base of small
subunit ribosomal RNA gene sequences from fungal species
identified as being common to indoor environments and/or
having potential adverse health effects. Data,  thus far, in
sufficient sequence diversity to allow the construction of species-
specific probes. (EPA Contact: Gerard N. Stelma, Jr., EMSL,
513-569-7384)
Exposure Assessment Research
Development of Methods for Recovery of Aerosolized Fungi

EMSL and researchers at Georgia State University have been
evaluating a  variety of commercial and  experimental  growth
media.  The  goal  is  to  develop a standardized  method for
collecting the broadest possible spectrum of indoor fungi.

The media were first tested for their ability to quantitatively
recover aerosolized fungi  commonly found in indoor air. The
best media are now being evaluated in the field to determine
which recover the broadest spectrum of fungi.

Field tests conducted in a number of buildings in the Southeast
U.S. are nearly complete. The results indicate that a set of three
media used concurrently allows the best recovery of the widest
variety of fungal species. This set of media will be evaluated in
a second independent laboratory in 1994. (EPA Contact: Gerard
N.  Stelma, Jr., EMSL, 513-569-7384)

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   Exposure Assessment Research
   Development and Testing of a Personal Whole Air Sampler

   Research Triangle Institute and AREAL have developed and
f   valuated a small, lightweight personal whole air sampler. The
^•"sampler can be worn to monitor personal exposures to VOCs and
   is suitable for large-scale population-based exposure studies.

   The prototype sampler is 25.5 cm high, 22.5 cm wide, and 7.5
   cm deep. With a 1-L SUMMA sample canister in place, the unit
   weighs 3.35 kg.   The unit  uses  rechargeable batteries that
   operate for approximately 16 hours.  The batteries, electronics
   module, and flow controller are enclosed in a plastic case.  The
   sampler can be placed in a laptop computer carrying case or
   carried over the shoulder.  The unit could also be used as a
   compact microenvironmental sampler.

   Laboratory testing of the unit demonstrated that the sample flow
   rate was not affected by temperature or the activity of the person
   wearing  the  sampler.    Recoveries of methylene  chloride,
   chloroform, 1,1,1-trichloroethane, benzene, n-octane, o-xylene,
   n-decane,  and Q-dichlorobenzene averaged 89% or higher for
   three final prototype samplers. Recoveries were slightly lower
   for vinyl chloride (74%) and n-dodecane (82%). The precision
   for the three prototype samplers was excellent during laboratory
   tests.  Further evaluation of the sampler is required to  fully
   validate its performance under field conditions. (EPA Contact:
   Andy Undstrom, AREAL, 919-541-4866)
              Flow Set Point
              Display Button
                                         Sampler   Mass Flow
                                         Intel    /Controller
     25.5 cm
               Summa-Polished
               Canister (1 liter)
                                                     Electronics
                                                     Module
                                                     Batteries
                                                     Battery
                                                     Charger
                                                     Connector
                                                   T  Depth
                                                   (Front to Back)
                                                     \  7.5 cm
                  Personal Whole Air Sampler.
Health Effect* Research
Results of EPA Carpet Emissions Tests

In  1992 Anderson Laboratories,  a private  testing  company,
reported that  the off-gassing of  certain "complaint" carpets
caused sensory and pulmonary irritation, neurobehavioral effects
and, in the most extreme cases, death, in exposed mice. Based
on  these test results, HERL and AEERL initiated a study to
replicate the Anderson results.

Results from the EPA tests showed that, based on the assessment
of respiratory irritation, neurobehavioral effects, measures from
a general toxicity screen, and evaluation of carpet contaminants
and emissions, there was no indication that exposure to emissions
from the two carpets tested posed a serious health risk.

In the HERL and AEERL study, two standard test methods using
laboratory mice,  one for estimating sensory irritancy and the
other for evaluating the neurotoxic potential of chemicals, were
coupled  with a  postmortem assessment.   The postmortem
evaluation included measurements of hemoglobin, serum clinical
chemistries, blood and lung lavage white cell counts,  organ
weights, and a gross necropsy with a microscopic evaluation of
all  major organs.

Three tests were  run: two with preheated carpet emission
exposures and one with a preheated control exposure. No toxic
effects were observed from exposure to the two tested carpets.
However,  clinical  chemistry and histopathological  alterations
were observed with exposure to both the control air and the
carpet  emissions   when   compared   to  the  non-exposed,
unrestrained control mice.   These results indicate  that the
alterations were caused by the exposure procedure rather than
the carpet emissions.

A detailed chemical and microbial evaluation of the carpets and
their emissions  was also performed.   Pesticide residues,
microbiological flora, and over 200 VOCs were present, but at
insufficient quantities to result in acute toxicity.

A technical paper, detailing the EPA study, has been submitted
to the Journal of the American Industrial Hygiene Association
and should be  published in  1994.   To  assist  in  better
understanding the varying  results between  the EPA and  the
Anderson tests, the next step  for EPA researchers will include
discussions with  physicians with experience in treating patients
that associate  health problems  with  carpet exposure. (EPA
Contact: Robert Dyer, HERL, 919-541-2760)

Health Effects Research
Health Effects Research on Exposure to NO2

Nitrogen dioxide  (NOj)  is a common  indoor air pollutant,
especially in homes  with unvented  combustion  appliances.
Epidemiological  studies suggest  that children  living in  homes
with elevated  levels of NO2 are more prone to  respiratory
infections than children living in homes with lower levels of
NO2.
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The objective of this study by HERL was to investigate whether
inflammation is induced by exposure to 2.0 ppm of NO2 and
whether alveolar macrophage host defense functions are altered.

In this study, 10 healthy adults (males and females, 22-35 years
old) were exposed to either 2.0 ppm of NO2 or filtered air for 4
hours while undergoing intermittent moderate exercise.  Changes
in a number of cellular and biochemical parameters, in both the
airways and alveolar region of the lung, were measured.

Cells and fluid lining the lung passages of the volunteers were
removed by bronchoalveolar lavage 16 hours after the exposure
to NO2.  The  lavage was divided into  two parts: one which
samples  primarily the  large airways of the lung  (bronchial
fraction) and  one  which  samples the gas  exchange region
(alveolar fraction).  Subjects exposed to NO2  had a 3-fold
increase  in inflammatory cells  (neutrophils), and  a  1.5-fold
increase in oc-l antitrypsin, an anti-inflammatory protein, in the
lungs. There  were no  other changes in cells or biochemical
mediators found  in  the bronchial fraction, and  no significant
changes  found in neutrophils or biochemical mediators in the
alveolar  fraction. However, alveolar macrophages,  the body's
first line of defense  against inhaled microorganisms, showed a
decrease in ability to engulf yeast particles as well as a decrease
in production  of superoxide anion, a compound involved in
killing microorganisms.

The results of this study showed evidence of mild inflammation
in the large airways but not the alveoli of humans exposed to
NO2. In addition, NO2 exposure resulted in a decrease in ability
of alveolar macrophages to engulf and kill microorganisms.

A complete copy of this paper is available in the Indoor Air '93
Proceedings. (EPA Contact: Robert Devlin,  HERL, 919-966-
6255)
 Risk Assessment Reieareh
 Use  of  a High-Volume  Small  Surface  Sampler  for  the
 Microbiological Evaluation of Dust

 Research Triangle Institute and ECAO have adapted a high
 volume  small surface sampler for collection of microbials in
 surface dust. The sampler was previously developed by AREAL
 for the collection of residential carpeted and non-carpeted surface
 dust  for pesticide and lead analysis. The major adaptations
 involve disinfecting the unit, using sterile polypropylene bottles
 to collect samples, and special bags on the exhaust of the unit.

 Results  show that the  sampler  can be used to collect surface
 dusts for the  analysis  of viable molds, yeasts,  bacteria,
 endotoxins, and dust mite guanine on both carpeted and non-
 carpeted surfaces.  Protocols for using the sampler are being
 developed. In addition, bioaerosol monitoring will allow the
 relationship   between   surface   and   airborne  microbial
 concentrations to be evaluated.
The sampler has been tested  on surfaces in two buildings
(designated as A and B). Building A has routinely maintained
carpeted and tiled floors. The carpeted floor surface of Building
B did not appear to be routinely maintained and was noticeably
soiled.Results from the sampling are shown in Figures 1, 2,
3 for surface dust loading, fungi, and endotoxins, respectively.
The microbiological composition of the surface dusts from the
buildings was found to be similar to that of ordinary outdoor
dirt. Microbial concentrations were higher in the carpet floor
dust than in tile dust in both buildings. Dusts in building A had
insignificant levels of endotoxin; however, Building B levels are
elevated. Dust mite guanine was not detected in any of the dust
samples. (EPA Contact: Mike A. Berry, ECAO, 919-541-4172)
-
Btdg A BWfl A
Carpet Tito

BMgB
Carpet


             Figure 1. Surface Dust Loading (g/m2)
    1.00E«7

    1.00W

    1.00E+5

    LOOM

    LOOM
                  BldgA
                  Carpet
BWfl A
Tito
BkJgB
Carpet
       Figure 2. Fungi Concentrations (CFU/g of dust)
                   BldgA
                   Lowest
 BldgA
 Highest
 BldgB
 Carpet
         Figure 3. Endotoxin in Surface Dust (ug/g of dust)
                                                         o
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   Solutions
   Pollution Prevention Research

 ^^AEERL is researching various pollution prevention techniques
4J-C-M  equipment or technology changes,  process or procedure
   modification, reformulation or redesign of products) in order to
   reduce indoor air pollution  through the  development of low-
   emitting  or low-impact  materials.   AEERL has  initiated
   cooperative agreements in Tour different  project areas for this
   research: aerosol consumer products, composite wood products,
   office equipment and products, and textiles.

   Aerosol  Consumer Products - The three  objectives of this
   research project are to: 1) characterize emissions from aerosol
   consumer products as a function of time; 2) develop methods and
   models to measure and predict emissions and personal exposures;
   and 3) develop pollution prevention  techniques and guidelines for
   the manufacture and use of these  products.  The research is
   being  performed by  Georgia Tech Research  Institute,  the
   University of Illinois,  and Purdue "University.  (EPA  Contact:
   Kelly Leovic, AEERL, 919-541-7717)

   Composite Wood  Products -  This' project focuses on  the
   development  of low  emitting/low impact composite wood
   products.  A product  list will be developed and  screened to
   determine emission characteristics and  pollution  prevention
   opportunities.  Products  offering  opportunities for pollution
   prevention will then be selected for further research. Studies of
   manufacturing  processes  then  will  be  implemented,  and
   "•^commendations for lower emitting products will be made. The
 ^^search will be conducted by Research Triangle Institute. (EPA
   Contact:  Betsy Shaver, AEERL, 919-541-7915)

   Office Equipment and Products -  The  objectives of this
   research  project are to collect emissions  data from office
   equipment and  products,  to identify  the  sources of  these
   emissions, and to develop pollution prevention approaches to
   reduce or eliminate emissions from selected equipment/products.
   The research will be conducted by Research Triangle Institute
   and Underwriters Laboratories.  (EPA Contact:  Kelly Leovic,
   AEERL, 919-541-7717)

   Textile Products -  Five research projects are underway at the
   College of Textiles at North Carolina State University: 1) VOC
   emissions (e.g., formaldehyde) from finishes used on fabrics -
   A number of fabric and finish combinations have been surveyed
   and five have been selected for further study;  2) Fiber-based
   alternatives for plywood and particleboard - Initial research has
   resulted in several potential products, and these products will be
   tested  for structural  characteristics and  VOC  emissions; 3)
   Fusion bonding equipment -  Emissions will be characterized for
   the most common fusion bonding  materials, and research will
   determine process changes to reduce emissions; 4) and 5) Effects
   of  physical  and   chemical  structure  on  adsorption  and
   emissioncharacteristics of textiles -  Selected materials will be
 (^   jted  and a  model will be developed. (EPA Contact: James
     "lite, AEERL, 919-541-1189)
Solutions
Evaluation of In-Duct Paniculate Air Cleaners

AEERL has conducted  an extensive evaluation of in-duct air
cleaners. The  evaluation included determining efficiency as a
function  of particle diameter for both  clean and  dirty air
cleaners. The  differential pressure across the  filters was also
evaluated because of its effect on energy consumption and the
quantity of air moved through the filter.  Commonly used air
cleaners were  included in the study: electrostatic precipitators
(ESPs), high efficiency filters, common furnace filters, industrial
American  Society  of   Heating,   Refrigerating,   and  Air
Conditioning   Engineers   (ASHRAE)   rated  filters,  and
electrostatically augmented filters.

The ESP  air  cleaners offered the highest  particle collection
efficiency for all particle diameters and the lowest pressure drop.
The performance of the ESPs was not affected by dust loading.
The ESPs did, however, generate a few parts per billion of
ozone. The ozone can be controlled by carbon filters  located
after the air cleaner. The filters would require occasional (i.e.,
annual) changing.

The high efficiency filters provided high  particle  collection
efficiency but  had much higher pressure drops than the ESPs.
Commonly used furnace filters and the industrial ASHRAE rated
filters had low particle collection efficiency, especially in the 0.2
to 2 /tm diameter range.

The electrostatically augmented air cleaner based on  electret
technology provided improved performance  compared to a
furnace filter  when clean.  However, the performance of the
filter was significantly reduced when the filter was dirty. The
other type of  electrostatically augmented filters tested  did not
show any significant improvement compared to a furnace filter.
In addition, the pressure drops across the filter increased as the
filter became dirty.
   100
                                              Furnace Fiter
                                              1   -w-
                                                 Etectret
                                              2   _*_
                                             Self Charging fitter
                                              3   —•—
                                              ASHRAE 40%

                                              ASHRAE 65%

                                              ASHRAE 95%
                                              O   ~L"1*'
                                                  ESP
     0.010.02  0.05 0.1  0.2   0.5  1   2
               Particle diameter ((jm)
Performance of Various In-Duct Paniculate Air Cleaners.
                                                            Page5

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The major conclusions from the evaluation are:

•   ESPs and high efficiency filters are the only air cleaners that
    provide high (>90%) collection efficiency for particles in
    the 0.2 to 2 pm diameter range.
•   High efficiency filters significantly increase  the pressure
    drop in  the  heating,  ventilating, and  air-conditioning
    (HVAC) system which increases fan motor amperage draw
    and reduces total air flow. The ESPs do not.
•   Electrostatically augmented air cleaners do not appear to
    provide significant performance  benefits compared  to
    common filters, especially when they become  dirty.
•   Particle collection efficiency of all filters, except the electret
    filter and ESP, increased as the filters became dirty.

The test methods developed during this study will form the basis
for an air cleaner evaluation test method recommended to the
private sector.  (EPA Contact: Leslie Sparks, AEERL,  919-
541-2458)
Catalog of  Materials  as Potential  Sources  of Indoor  Air
Emissions

A  variety  of  research  efforts,  both  in  the  U.S.   and
internationally, have focused on materials as potential sources of
indoor air emissions.  These research efforts typically do not
concentrate on any one group of products or standard  sampling
and analytical methods. In addition, there is little consistency in
the terminology used to describe the products tested.  This lack
of consistency in test methods and terminology makes the data
difficult to compare.
                    As a result, AEERL published the Classification of Materials as
                    Potential Sources of Indoor Air Pollution (EPA-600/8-90-074;
                    NTIS   PB91-125708)  in  1990.  This  report  presented  a
                    classification of building materials, fixtures and furnishings,
                    consumer products used or found in homes or offices,
                    of their potential to emit.

                    Materials and products considered to be potential sources of
                    indoor air emissions were then selected for further study. The
                    objective then was  to:   1)  generate  a useful  scheme   for
                    presenting the variety of material sources in homes and offices;
                    and 2) present available usage, constituent, and emissions data
                    for these material sources. The results of this second study are
                    to be presented in Volumes I and II of the Catalog of Materials
                    as Sources of Indoor Air F.rr^issjnns. Volume I of the catalog
                    (EPA-600/R-93-108a;  NTIS  PB93-212041)  was published in
                    June 1993, and contains sections  on: insulation products, wall
                    coverings, resilient floor covering, carpet, adhesives, caulks and
                    sealants, and pesticide products.   Volume II  of the Catalog, to
                    be published early in 1994, will contain sections on:  wood
                    products, paints and coatings, foam products, fabricated  rubber
                    products, and mineral products.

                    Each  section presents  a classification scheme for the product
                    category,  sales and usage volume data,  qualitative data  on
                    product composition, and quantitative and qualitative data on
                    emission  rates.  Emissions information  is presented only for
                    VOCs as these are the compounds most likely to be emitted from
                    materials  found in homes and office buildings. Data  tables
                    summarizing  available emissions and constituent  data
                    provided and are organized according to a product classificati
                    scheme. (EPA Contact: James White, AEERL, 919-541-1189)
                     Summaries of ORD Papers in Indoor Air '93 Proceedings
24 papers at Indoor Air '93 la Helsinki,
Finland.  Below *re summaries of those
         which  should  be  available
             from  National Technical
Information  Service  (see  address on
pagell). To purchase the proceedings
from the organizers of Indoor Air *93,
write or fax your request to: Indoor Ail
'93, P,O, Bex  87*  SF-02IS1 Espoo,
Finland (Fax: +358-CM51 3611).

The summaries we organized into Mb
following five sections: Science /Policy,
Source  Characterization,   Exposure
Assessment,  Health   Effects,    and
Solutions.
Science/Policy

Establishing  Priorities  in the  U.S.
EPA's   Indoor  Air  Engineering
Research Program (NTIS PB93-221984)
- AEERL consulted  researchers within
government, industry, and  academia to
help identify and rank priority program
areas for  IAQ  engineering research.
Specific   program   elements   include
chemical   source  characterization,
bioresponse  testing,   air  cleaning,
ventilation, biocontamination, cost/IAQ
modeling,  and  pollution   prevention.
Recommendations included expansion of
AEERL   biocontaminant   prevention/
control research. Lead Author  & EPA
Contact: Michael C.  Osborne (919-541-
4113).
Indoor Air Quality: Exploring Policy
Options to Reduce Human Exposures -
This  plenary  paper   presents  factors
policymakers   must    consider   in
establishing IAQ policies and the role
researchers can play in  ensuring policies
are based on the best available science.
Examples cited are environmental tobacco
smoke, radon, problem  buildings, and
ventilation standards.  Lead Author  &
EPA Contact: Kevin Teichman (202-260-
7669).

Indoor    Air   Quality:   The  U.S.
Environmental  Protection   Agency's
Research Strategy - EPA's IAQ research
strategy is to identify,  characterize, and
compare  the health risks associated
exposures to indoor air pollutants so
risk assessors  and risk  managers  can
                                                        Page 6

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   make informed decisions to protect public
   health.  This  strategy  emphasizes  the
   quantitative   evaluation   of  indoor
   exposures and associated health effects as
   the basis for relative risk assessment of
     th pollutants and pollutant mixtures.
   For  pollutants for which the potential
   risks  are relatively  well characterized
   (e.g.,  asbestos,  radon,  environmental
   tobacco  smoke,   and   formaldehyde),
   research  efforts focus  on  developing
   approaches to  prevent or reduce indoor
   exposures.  Lead Author, Ken  Sexton.
   EPA Contact: Kevin Teichman (202-260-
   5900).
   Source
   Assessment  of  Fungal  Growth  on
   Ceiling Tiles Under  Environmentally
   Characterized Conditions (NTIS PB93-
   222024) - Static  chambers with defined
   relative humidity, temperature, and light
   conditions are being used to study  the
   effect  of  building  environment  on
   microbial growth. Four types of ceiling
   tile   (one   aged,   two  mineral
   fiber/crystalline  silica,  and  one  fire
   resistant) were placed in the chambers,
 ,,^llowed to equilibrate,  and inoculated
i^/ith  either   Penicillium  glabrum  or
   Aspergillus versicolor. The critical bulk
   moisture content for  organism growth
   varied depending upon tile type and test
   mold. Lead  Author,  K.  Foade. EPA
   Contact:  John C.S.  Chang (919-541-
   3747).

   Bioresponse  Testing of  Sources  of
   Indoor Air Contaminants (NTIS PB93-
   222032) - This paper reviews the concept
   of "bioresponse"  testing  of emissions
   from sources of indoor air contaminants.
   Examples  of bioresponse  methods that
   measure human,  animal,   or  in  vitro
   biological  responses to emissions  are
   briefly described. The potential value of
   bioresponse methods for evaluating health
   and sensory comfort in relation to indoor
   sources  is  discussed and  related  to
   product testing.  Lead Author  & EPA
   Contact: W. Gene Tucker  (919-541  -
   2746).

   Fundamental Mass Transfer Models for
 f***%loor  Air  Pollution Sources  (NTIS
 S"B93-221992) - A simple model based on
Pick's  Law  of  Diffusion has  been
developed for wet solvent-based sources.
In this model, the mass transfer rate is
assumed to be gas-phase  limited and
controlled by the boundary layer mass
transfer coefficient, the saturation vapor
pressure of the material emitted, and the
mass  of  volatile  material  remaining.
Results  of static and dynamic chamber
tests,  as well as test house studies,  are
presented. Lead Author & EPA Contact:
Bruce A. Tichenor (919-541-2991).

International Comparison Experiment
on the Determination of VOCs Emitted
From Indoor Materials Using Small
Test Chambers (NTIS PB93-222073) -
An interlaboratory comparison used small
test chambers to  assess the agreement
among  laboratories  for  characterizing
VOCs emitted from indoor materials and
products.  Results from this paper  are
highlighted  under   Research   Project
Highlights on pages 1 and 2 (International
Comparison of Small Chambers).  Lead
Author, Angelo Colombo. EPA Contact:
Bruce A. Tichenor (919-541 -2991).

Modeling of  Alkane Emissions from a
Wood Stain - The  effects of organic
emissions   from   wood   stain  were
evaluated in a test bouse. Concentrations
of three alkane species - nonane, decane,
and undecane -  were measured  as a
function of time. Results showed that the
test house concentrations can be simulated
by an integrated IAQ model taking into
consideration source, sink, and ventilation
effects.  Sink effects  in the test house
were   significant,   and    an   inverse
relationship between the test house sink
strength and the volatility of the  three
alkane species was found. Lead Author &
EPA Contact: John C.S. Chang (919-541-
3747).
Exposure Assessment

A New House Dust Collection System
and its Use in a Study of Asthma in
Dust   Mite  Sensitive  Children  in
Raleigh,  North Carolina - A prototype
dust collection system, the House Dust
Vacuum One, was designed for use in a
study   to  investigate   the  relationship
between house dust mite antigen levels
and the presence of wheeze in dust mite
sensitive   children.   No   significant
differences in mean micro-environmental
dust mite antigen  levels were observed
between samples  from  the  homes  of
wheezers and nonwheezers. The new unit
was  determined to be  well  suited for
surface dust  and  dust  mite  antigen
collection   studies.    Lead  Author,
Frederick W. Henderson.  EPA Contact:
Andrew B. Lindstrom (919 541-4866).

Assessing  Potential  Exposures  from
Routine Use  of  VOC-Contaminated
Groundwater - Residential measurements
were made to assess potential exposures
from the routine household use of VOC-
contaminatedgroundwater. Measurements
were based on a single 20-minute shower
using  groundwater containing 185-367
pg/L benzene. Personal doses estimated
over the 6-hour experiment for occupants
of the bathroom and  living  room were
< 135  /ig  and  < 80  /ig  benzene,
respectively.  The  20-minute  shower
resulted in an estimated total dose of 281
jig benzene (113 /ig for inhalation and
168  /ig for dermal).  Lead Author and
EPA Contact: V. Ross Highsmith (919-
541-7828).

Association of Personal and Workplace
Characteristics with  Reported Health
Symptoms   of   (771   Government
Employees in Washington,  DC - An
IAQ  questionnaire was completed by
6771 government employees. Regression
analyses  on  12   clusters   of   health
symptoms indicated that both personal
and   workplace   characteristics  were
associated with symptoms. The variables
associated with  the largest  number  of
symptoms at the two agencies studied
were dry air/dusty office, chemical/paint
odors, hot stuffy air,  and sensitivity to
chemicals.  Other  variables  that were
often   significantly   associated   with
symptoms were glare,  carpet/drape odor,
dust/mold allergy, career frustration, and
job pressure/conflict.   Lead  Author &
Contact: Lance Wallace  (703-341-7509).
EPA Base Program-Collecting Baseline
Information on Indoor  Air Quality -
EPA's Office of Radiation and Indoor Air
and AREAL have begun a major study of
                                                          Page 7

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IAQ and occupant perceptions in public
and commercial office buildings. A set of
core measurements will be made for this
Building   Assessment   Survey   and
Evaluation  (BASE). The  cross-sectional
study will  include  approximately 200
buildings over the  next  three  to five
years.   Measurements   include
environmental   conditions   in   a
representative  sampling space in each
building, an occupant questionnaire, and
characterization of the building and  the
HVAC system. The information collected
will be coded for  confidentiality and
included in a publicly accessible database.
Lead Author,  Susan E. Wonble.  EPA
Contact: RossHighsmith(919-541-7828).

Evaluation of "Before"  and  "After,"
Occupant,   IAQ,   and  HVAC
Parameters in a  Building Remediated
Because of Unacceptable IAQ   -  An
Augusta, Maine, office building with 810
occupants   has    undergone    many
IAQ/HVAC diagnostic evaluations during
the past ten years.  In 1992, the owner
upgraded the building's HVAC system.
To assess  conditions  in  the  building
before remediation, an HVAC evaluation,
an   occupant   questionnaire,   and
measurement of VOCs, microbial levels,
inhalable particles,  and  work  station
thermal comfort were conducted. After
remediation in  1993, the evaluations will
be repeated and results compared. Lead
Author, Frederick T.  McKnight.  EPA
Contact: Ross Highsmith (919-541-7828).

Indoor  Concentration  Modeling   of
Aerosol Strong  Acidity  -  A model,
developed   for   estimating    indoor
concentrations  of acid aerosol in a semi-
rural community in PA, was applied to
estimate indoor concentrations of aerosol
strong acidity (H+) in suburban NJ. The
purpose was to assess the applicability of
the model for predicting H+ exposures in
a suburban environment and to evaluate
the model's performance for daytime and
nighttime periods. The model applied to
the site in NJ did not predict the indoor
H+ concentrations as well  as it did for the
experiment for which  it was developed.
Lead Author &  EPA Contact: Michael
Zelenka (919-541-1326).
Indoor,  Outdoor,  and  Personal Air
Exposures to Particles, Elements, and
Nicotine for 178 Southern California
Residents  -  Personal,   indoor,  and
outdoor  concentrations  of  inhalable
particles,  associated  elements,   and
nicotine were measured for a sample of
178  persons representing  nonsmoking
residents  of  Riverside,  CA.  Newly
designed  personal   monitors   were
employed.   Personal  exposures  often
exceeded concurrent indoor and  outdoor
concentrations, both for particles and for
14 elements. The increase is due in part
to personal activities such as cooking and
sharing a home with a smoker. Personal
and indoor nicotine  levels were  elevated
for  persons  reporting   exposure  to
environmental tobacco smoke (ETS) and
living  in homes with  smokers.  EPA
Contact: Lance Wallace (703-341-7509).

Sources   and   Factors   Influencing
Personal  and  Indoor   Exposures to
Particles,  Elements  and  Nicotine:
Findings from the Particle Team Pilot
Study - During the fall of 1990, a large-
scale   field   monitoring  program  to
characterize   personal   exposures  to
inhalable  particles  with aerodynamic
diameter less than 10 /im was conducted
in Riverside,  CA.  Results show that
personal   exposures  to   nicotine  are
strongly  related  to  percent time  spent
indoors in the presence of a  smoker.
Modeling results also indicated that air
exchange  rate,  amount  of   dusting,
vacuuming  and  cooking  affect indoor
particle  concentrations.   Lead  Author,
Haluk  Ozkaynak. EPA Contact: Lance
Wallace (703-341-7509).

Health Effects

Cotinine  Elimination Following ETS
Exposure in  Young  Children  as a
Function of Age, Sex, and Race - The
determination of the elimination half-life
(tl/2) of cotinine from urinary excretion
data is  useful  in  correlating  urinary
cotinine concentrations to estimate ETS
exposure.  Currently,   quantitative
relationships between  urinary  cotinine
excretion and ETS exposure in  children
have not been determined. This  research
determined the cotinine tl/2 in children up
to  three  years  of age  using  urinary
cotinine  excretion data.  Lead  Author,
Albert M. Collier. EPA Contact: George
M. Goldstein (919-541-6204).
Electronically Enhanced Measures o
Eye Irritation  for  Use in Studying
Subjects Exposed to VOCs -  Simple,
rapid,   and   objective   methods   of
measuring tear-film break-up time  and
quantitating eye  irritation are needed in
order to  study  the  health  effects  in
individuals  that  complain  of  ocular
irritation following  exposure to  VOCs.
The described method uses miniaturized,
closed circuit television to non-invasively
measure  tear film  break-up  time.  A
procedure   that   uses   computer
enhancement  of eye  photographs  to
objectively score changes in  eye redness
is also described. Lead Author & EPA
Contact: George M. Goldstein (919-541-
6204).
Evidence for Mild Inflammation and
Change   in  Alveolar  Macrophage
Function in Humans Exposed to 2 PPM
NO2 - In this study, 10 healthy volunteers
were exposed to either 2.0 ppm NO2 or
filtered air for 4 hours while undergoing
intermittent  moderate  exercise.
project is  highlighted  under
Project Highlights beginning on page 3
(Health Effects Research on Exposure to
NOj).  Lead  Author,  Susanne Becker.
EPA Contact: Robert Devlin (919-541-
6255).

Mite Antigen Concentrations in House
Dust and the Occurrence of Wheezing
in Children  with Dust Mite Allergy -
This  study  examined  the  relationship
between dust mite antigen concentrations
in house dust samples and the occurrence
and frequency of wheezing in 58 children
with dust mite allergy. Dust samples were
obtained  from six sites in each home:  the
child's  mattress,   blanket,   pillow,
bedroom floor, and the recreation room
couch  and  floor.  Differences  in  the
degree of home environmental contamin-
ation with mite  antigen did  not account
for  differences  in  the occurrence  or
frequency of wheezing,  bronchial hyper-
activity, or lung function among children
with dust  mite allergy. Lead Author
Frederick W. Henderson. EPA
Andrew B. Lindstrom (919-541-4866).
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   Neurobehavioral    and   Subjective
   Reactions of Young Men and Women
   to  a Complex Mixture of  Volatile
   Organic  Compounds  -  The  neuro-
    tthavioral and subjective reactions of 26
   male and IS female subjects to  4-hour
   controlled exposure to clean air and 25
   mg/m3 of VOCs were compared. Subjects
   reported  greater  odor   intensity  and
   unpleasantness; increased eye, nose and
   throat irritation; and reduced IAQ during
   VOC   exposure.    Neurobehavioral
   performance was not affected by VOCs.
   Contrary to previous reports, women did
   not express more sick building syndrome
   type complaints  than  men during VOC
   exposure. Lead Author & EPA Contact:
   D. Otto (919-541-6226).
   Pulmonary, Respiratory, and Irritant
   Effects of Exposure  to  a Mixture of
   VOCs  at Three  Concentrations in
   Young Men - The objective of this study
   was to determine if  the  frequency of
   human respiration is affected by exposure
   to a mixture of VOCs (0,  12, 24 ppm).
   Twenty subjects were exposed to the mix
   for 4 hours during which respiration rate
   was   collected   continuously   and
 "  questionnaire data were obtained hourly.
W Results indicate no effect on respiratory
frequency. However, there was a linear
increase in respiratory eyeblink frequency
with  time  in the  chamber.  Eyeblink
frequency was elevated  by exposure.
Increased eye irritation, odor strength,
and degradation of IAQ were reported in
comparison to control  exposures.  Lead
Author & EPA Contact: J.D. Prah (919-
541-6244).

Time Course of Odor and Irritation
Effects  in  Humans  Exposed  to  a
Mixture   of  22  Volatile  Organic
Compounds - Ratings of IAQ, odor and
irritation intensity,  and other variables
were obtained before and during 4 hour
exposures  to  clean  air  and   three
concentrations of a mixture of VOCs.
Perceived odor intensity decreased, and
irritation intensity  increased  gradually
during VOC  exposure in a dose-related
fashion. Odor and irritation appear to be
primary determinants of perceived  IAQ.
Lead  Author  &  EPA Contact: H. Ken
Hudnell (919-541-7866).

Solutions

Evaluation of Ventilation Performance
for Indoor Space (NTIS PB93-212751) -
Ventilation   performance  depends  on
room geometry, ventilation method, and
operating conditions, as well as location,
source   strength,   and   types   of
contaminants. A menu-driven ventilation
model was developed that is capable of
determining the turbulent flow field  and
time-dependent/steady-state contaminant
concentration    distributions   within
isothermal  indoor space. Lead Author,
Toshiaki Yamamoto EPA Contact: Leslie
E. Sparks (919-541-2458).

Status  of ASHRAE  Standard 62 -
Ventilation for Acceptable Indoor Air
Quality  (NTIS  PB93-222040)  - This
paper describes the purpose, history, and
major features of ASHRAE Standard 62.
The  status of the review and revision
process  as of January 1993  and the
current  working  outline of the revised
standard    are     discussed.     The
complementary   roles  of  ventilation,
source management, and air cleaning are
emphasized.  Extending  the  standard
beyond  ventilation  system  design  to
include  operation and  maintenance of
buildings and ventilation systems  is also
projected. EPA Contact: W. Gene Tucker
(919-541-2746).
                            Summaries of Recent EPA Indoor Air Workshops
   Indoor Air Quality/Pollution Prevention Workshop

   To assist AEERL in identifying potential areas of research for
   applying pollution prevention to IAQ, a 2-day workshop was
   held March 9-10, 1993. The 64 Workshop attendees included
   scientists and  engineers with experience in IAQ, pollution
   prevention, and/or industrial processes.

   The  Workshop  covered background information  on  IAQ,
   pollution prevention, and AEERL1 s strategy to combine the two.
   Participants were then  placed into one of six workgroups to
   focus on pollution prevention research in the following topic
   areas:  adhesives and sealants,  building materials,  consumer
   products, furniture,  office equipment, and  textiles.   On  the
   second day, an ad hoc workgroup on biocontaminants was added
   because of participants'  interest.

   At the Workshop, a number of materials/products were identified
   as potential research options for applying pollution prevention
   techniques to improve IAQ. A ranking or prioritization of the
   .naterials/products suggested  was not included as part of  the
   Workshop.
                    AEERL will use the suggestions from the Workshop as input for
                    both lAQ/pollution  prevention  strategic planning and for
                    determining specific  program direction and  prioritization of
                    future research projects.

                    In summary, the major themes from the Workshop were:
                    •   There is  a desire  for  EPA to identify  the major  IAQ
                        problems.   Many  discussions focussed  on the  relative
                        importance of different IAQ sources.
                    •   Making the link between IAQ and pollution prevention was
                        difficult. More specific examples or case studies would be
                        helpful.
                    •   The workgroups  consistently identified a need for more
                        emissions  testing,  methods   development,   modelling,
                        consumer education, and source ranking.
                    •   The issue of proprietary information must  be considered in
                        developing a  pollution prevention research strategy for
                        indoor materials and products.
                    •   Participants felt that research on preventing biocontaminant
                        growth is important.
                    •   The Workshop served to initiate interaction between IAQ,
                        pollution prevention, and industry researchers.
                                                          Page 9

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Detailed suggestions from each of the seven workgroups are
summarized below.  The  suggestions are  not meant as  a
comprehensive listing or ranking of AEERL research priorities,
but only as summaries of the  topics discussed by Workshop
participants.

The following pollution prevention options were suggested for
adhesives and caulks/sealants:  material substitution;  material
elimination (e.g., eliminating unnecessary chemicals); innovative
technologies (e.g., producing a carpet with an attached stick-on
pad, producing adhesives without solvents); process substitution;
and packaging reduction.

The biocontaminants workgroup concluded that research should
concentrate on:  improvement of biocontaminant measurement
techniques; development of building codes to prevent places in
buildings that encourage biocontaminant growth; development of
effective building cleaning schedules; and public education.

The building materials workgroup discussed vinyl and fabric wall
coverings;  HVAC systems; interior panels; ceiling tiles;  and
electrical wire jacketing.  General suggestions included research
on the source characteristics of a material and the potential sink
characteristics; coating or sealing  exposed surfaces to prevent
VOC  release; easy-to-clean designs; and consideration of total
surface area of material used, the toxicity of emitted compounds,
and the emission mechanisms (e.g., physical, chemical).

Pollution prevention suggestions for consumer products included:
packaging, delivery, storage, and disposal  issues;  consumer-
based performance standards development;  total cost benefit
assessment; labeling; consumer education on proper product use;
source  characterization; and  test method development.

The following products were suggested for potential research by
the furniture workgroup: finish coatings, upholstery, institutional
and residential  furniture,  and  cushioning. Research should
identify  all emitters  and emission rates,  then  the  critical
emissions  and  products.    The  next  step  is  to  identify
manufacturing changes that will reduce emissions.

The  office equipment  workgroup  suggested  researching:
blueprint machines; dry printers and copiers; toner emissions,
increasing toner transfer efficiencies, and the secondary toner
market; equipment bakeouts; propellants and other dispensing
agents; and paper proliferation in the office.  Emissions research
should   include:   emission   characterization,    chemical
transformations  and interactions  with  emissions  from other
sources, and product aging.  The workgroup also recommended
designing products  so that  they  are  easily remanufactured;
studying the relationship between equipment miniaturization and
emissions; and understanding cross media and energy impacts,
toxicity, and flammability issues.

The  textiles workgroup  suggested the  following research:
measure primary emissions from textiles and create a database;
investigate source/sink behavior; understand  exposures  and
health effects;   conduct  life-cycle analyses considering  use
patterns and exposures, consumer and end-use issues,  aging,
maintenance, and raw materials; finishes (e.g., formaldehyde,
fire retardants), and the use of mechanical rather than chemical
finishes;  process changes (e.g.,  pressure drying rather  than
atmospheric drying);  and process design changes (e.g.,
optimally designed machines so that fabric does not need to
sized for different uses).

Proceedings from  the Workshop  (EPA-600/R-93/198; NTIS
PB94-114782)  are available  from  the  National  Technical
Information Service (NTIS). (See address on page 11.)
Ventilation and IAQ Workshop

AEERL co-sponsored a Workshop on Ventilation and IAQ with
the University of Illinois Bioenvironmental Engineering Research
Laboratory (BERL).  The Workshop was held September 14-16,
1993, in Raleigh, NC.

Over 80  IAQ researchers, HVAC industry representatives,
engineers   and   architects,   and   buildings   science  and
environmental professionals attended. The objective  was  to
review an analysis of ventilation technology systems prepared for
AEERL by BERL.

The analysis summarized emerging trends and technologies and
identified  research and development activities in  these HVAC
areas: system selection and application; design; construction and
installation; commissioning and testing, adjusting, and balancing-,
and  operations and  maintenance.  Non-industrial  ventilati
systems were the primary target of the document.

Workgroups  focused  on  the impact of ventilation systems on
IAQ  related  to  buildings  and  ventilation.  The  Workshop
identified  several areas of needed research:

•   Development of an acceptable definition of IAQ for industry
use.  It is important to define IAQ in terms of health risk, lost
productivity, and associated costs.

•   Design of more flexible HVAC systems to accommodate
building use changes and renovations.  For example, designs to
allow supply and return air to be properly installed and balanced
to match space alterations and expanded system capacity needs.

•   Emphasis on  life cycle  costing to  discourage least cost
engineering.  Installing the least expensive system can often lead
to IAQ problems. In addition, these systems are typically harder
to commission because of the lack of proper balancing and
distribution components, and they are often more difficult and
costlier to maintain.
 •  Development of improved field measurement techniques,
 instrumentation, and IAQ sensors.  The industry needs tools anc
 diagnostic procedures that are less costly, more reliable,
 have greater accuracy than current techniques.
                                                         Page 10

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   •   Encouragement of building owners and operators to provide
   continuous building commissioning and preventive maintenance.
   Building  owners  and  operators  need to  understand  that
,. „. commissioning of a facility does not end when occupancy begins.
   Many studies prove that continued good IAQ is dependent on
"**" continued preventive maintenance.

   •   Increased technology transfer and communications among
   researchers and industry professionals.   Researchers need  to
   realize that the ultimate end user of IAQ research is an engineer,
   architect, or building owner and that economics, profit margin,
   and practicality are driving forces.

   Areas of emerging trends and technological advances discussed
   at the workshop included development of:
                               •   Computer-based automated control and analysis system for
                               continuous monitoring and evaluation of IAQ.

                               •   Alternative ventilation   strategies  include  displacement
                               ventilation,  under-fioor supply  distribution,  and  dedicated
                               occupant environmental control systems for improved ventilation.

                               •   Advanced/enhanced filtration (particle, gas, and microbial)
                               technology to reduce outdoor air and energy requirements.

                               •    Continued use  of  experimental  computational  fluid
                               dynamics models to assist ventilation effectiveness research.

                               For additional information on the Workshop, contact Russell N.
                               Kulp at (919) 541-7980.
   Symposium on Measurement of Toxic
   and Related Air Pollutants

   This international symposium will be held
   May 2-6, 1994, at the Omni Hotel and
   Convention Center in Durham, North
   Carolina.  The symposium is sponsored
   by  AREAL  and the  Air  & Waste
   Management Association (AWMA) and
   will  include   oral  presentations   and
   exhibits.      Indoor   air   pollutant
   measurements  are  included  in   the
   program. For information, contact Bruce
   W.   Gay,  Jr., U.S.   EPA,  MD-80,
   Research Triangle Park, NC 27711 (919-
   541-2830).
             Upcoming ORD Meetings

           Symposium on Characterizing Indoor
           Sources and Sinks

           ASTM Subcommittee D22.05 on Indoor
           Air  will be holding a  Symposium on
           Characterizing Indoor Sources and Sinks.
           The Symposium will be held September
           25-28, 1994, in Washington, DC, and
           will be chaired  by Bruce Tichenor of
           AEERL.  Topics will include:  chamber
           design,   characterization,   and
           performance;    operation;   data
           interpretation and application; and other
           topics related to emissions testing.  For
           information,  contact  ASTM  (215-299
           5413) or Bruce Tichenor (919-541-2991).
                                        Biocontaminant Workshop

                                        AEERL,   EMSL,  and   AREAL  are
                                        sponsoring a Biocontaminant Workshop
                                        in March 1994.  The objectives of the
                                        Workshop are to assist EPA in planning
                                        both short-term and long-term (beyond 3
                                        years)  research  in  the   areas   of
                                        biocontaminant measurement and control.
                                        Attendance at the workshop  will  be
                                        limited.   For information, contact John
                                        Chang (919-541-3747).
                                      Summaries  of Recent Publications
   This section proyidet
of recent
(*) Summaries  listing  "1992  Toxics
Measurement Symposium*  as a source
abbreviates   'Proceedings  of   the
AWMA/EPA International Symposium on
Measurement of Toxic and Related Air
Pollutants, Durham, N.C.,  May  3-8,
1992. EPA-600/R-92-131.'
                                          Source Characterization

                                          Fundamental Mass Transfer Model for
                                          Indoor Air Emissions from Surface
                                          Coatings - A simple model based on the
                                          boundary layer theory was developed to
                                          determine emissions from freshly applied
paints and coatings.  The model provides
a better fit to chamber-derived emissions
data than  an empirical first-order decay
model,  especially  over  the  decaying
portion of the concentration versus time
curve.  In this model, the mass transfer
rate  is assumed to be controlled by the
boundary layer mass transfer coefficient,
the  saturation  vapor pressure of the
material being emitted, and  the mass of
volatile material remaining in the source.
Static and dynamic chamber tests and test
house data indicate that the model can be
applied to  different products with similar
solvents. Source: Indoor Air (accepted for
publication).   EPA   contact:   Bruce
Tichenor, AEERL (919-541-2991).
                                                         Page 11

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 Exposure Assessment

Comparison  of Transfer  of Surface
Chlorpyrifos Residues From Carpet by
Three Dislodgeable Residue Methods •
The Dow drag sled, the California cloth
roller,  and   the  Southwest  Research
Institute polyurethane foam roller, three
sampling methods developed to estimate
the transfer  of  a chemical  from  a
contaminated  surface  to  the  skin, were
evaluated. The cloth roller was found to
be less suitable than the other methods
because its transfers exhibited greater
variability and were altered by orientation
of the roll relative to the lay of the carpet
fibers.  The  effect of  moistening  the
sampling media on transfer by the drag
sled and the polyurethane foam roller are
discussed.     Source:   1992  Toxics
Measurement   Symposium.'1'     Lead
Author,  D.  E. Camann.  EPA Contact:
Robert G. Lewis (919-541-3065).
Methodology  for  Determination  of
Polycydic Aromatic Hydrocarbons and
Other   Semi-Volatile   Organic
Compounds in House Dust - Analytical
methods  were validated  to determine
polycyclic aromatic hydrocarbons (PAH)
and   other   semi-volatile   organic
compounds (SVOC) in house dust. The
storage stability of three potential markers
(solanesol,  nicotine,  and cotinine) for
particulate-phase  ETS in house  dust was
also  examined.  Results  suggest that
cotinine  is  a  better  marker  for ETS
particles in house dust than nicotine and
solanesol  is not  a  suitable  marker.
Results  from a  small field study that
evaluated  the effect of smokers  in the
house on  PAH,  cotinine,  and nicotine
concentrations in  house dust are included.
Source:    1992  Toxics  Measurement
Symposium.*  Lead  Author,   Jane  C.
Chuang.  EPA Contact: Nancy K. Wilson
(919-541-4723).

Sampling,   Supercritical    Fluid
Extraction  and  GC/MS  Analyses  of
Indoor    Air    Semi-Volatile   Toxic
Organics - A method has been developed
to sample indoor airborne semi-volatile
toxic organics  followed by  supercritical
fluid extraction  and GC/MS analyses.
The sampling module, parameters used in
the wet chemistry preparation,  typical
quality assurance/quality control data, and
preliminary  results   from  several
categories  of homes (e.g., electric and
gas   heating/cooking   systems,
smoking/non-smoking)  are  discussed.
Source:   1992   Toxics   Measurement
Symposium.'"  Lead  Author,  V.  M.
Kanagasabapathy. EPA Contact: Robert
Chapman (919-541-6219).

The  Mutagenicity  of  Outdoor and
Indoor Air Samples Taken in Roanoke
During Wintertime -  The mutagenicity
of wintertime ambient air samples in
Boise,  ID,  and  Roanoke,  VA,  was
examined   using  the   Salmonella
mutagenicity assay. Twenty homes were
sampled in 10 matched pairs. Each pair
included one home  with  a combustion
heat  source (an oil heater, a woodstove,
or a fireplace),  and  the other  home
without.  Both the  extractable organic
matter   and   SVOC   samples   were
mutagenic,  and the level of mutagenicity
could be  associated  with  the  known
sources.   Source:      1992   Toxics
Measurement Symposium.1" Lead Author
& EPA Contact: Larry  D. Claxton (919-
541-2329).
Risk Assessment

Use of a High-Volume Small Surface
Sampler   for   the   Microbiological
Evaluation of Dust From Carpeted and
Non-Carpeted  Surfaces  -  This paper
discusses a building cleaning effectiveness
study being conducted  by ECAO. This
study is discussed under Research Project
Highlights  on page 4 (Use of a High-
Volume Small Surface  Sampler for the
Microbial  Evaluation of Dust). Source:
1992 Toxics Measurement Symposium.*
Lead  Author,  K.  E.   Leese.    EPA
Contact: M. A.  Berry (919- 541-4172).
Solutions

An Analytical Solution to Describe the
Pressure/ Flow Relationship in EPA's
Soil-Gas Chamber - An analytical model
has  been  developed  to  describe the
relationship between pressure differential
and  flow  rate in AEERL's  soil gas
chamber. The classic method of images is
applied   to   simulate   the   boundary
conditions   imposed  by  the   finite
dimensions of the chamber. The resulting
influence on constant pressure contours
and the streamlines is shown.   Source:
1992 Toxics Measurement Symposium.*
Author  &   EPA  Contact: Ronald B.
Mosley  (919-541-7865).

Case  Studies  of  Radon  Reduction
Research in 13 School Buildings -This
report details AEERL radon mitigation
research in 13 school buildings located in
Colorado,  Maine,  Minnesota,  Ohio,
South   Dakota,     Tennessee,   and
Washington state.   The objectives of the
research were to  better  understand  the
conditions under which HVAC systems
can be used for effective radon reduction
and  to   compare   the performance  of
HVAC  system control  of radon with
active subslab depressurization control in
the same building.  Source: EPA Report
(EPA-600/R-93-225).   Lead    Author,
Bobby  E.  Pyle.  EPA  Contact:  Kelly
Leovic (919-541-7717).
Case Studies  of  Radon  Reduction
Research  in Maryland, New  Jerse
and Virginia Schools - One school i
each of these states was selected for this
radon research project.  In two of the
schools the objective was to evaluate the
potential for modification of the school
HVAC   system   to   control   radon
concentrations.   The  third school was
recently constructed with radon resistant
features,   and  the  objective   was  to
evaluate   the  effectiveness  of those
features. Source: EPA Report (EPA-600/
R-93-211;  NTIS PB94-1 17363).  Lead
Author, David W. Saum. EPA Contact:
Kelly Leovic (919- 541-7717).

Characteristics of School Buildings in
the  U.S.  - To  guide AEERL's radon
mitigation   research   in  schools,
information on the physical characteristics
of  100  randomly selected  schools was
collected.  The results show: most school
structures  are   of   slab-on-grade
construction; gravel was used as subslab
fill material in approximately half of the
structures; approximately  80% of
schools have either central HVAC or unil
ventilators   capable    of   delivering
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'
conditioned outdoor air; and about 25%
of  the  schools  have subslab  footings
extending both  beneath the classroom
walls and along  the  corridors,  thus
 •omplicating the installation of a subslab
'depressurization  system.  Source: EPA
Report    (EPA-600/R-93-218)   Lead
Author,   Harry   Chmelynski.     EPA
Contact: Kelly Leovic (919-541-7717).

Comparison    of   Measurement
Techniques  for Soil Permeability  in
EPA's Soil-Gas Chamber  - Initial soil
permeability measurements in AEERL's
soil  chamber  yield  relatively  good
agreement between two methods.  One
method  uses  a set  of 23  point  probes
located  in a vertical plane and is  similar
to the standard practice of measuring  in
situ soil permeabilities. The other method
uses an arrangement designed to ensure
ideal geometric flow patterns and yields
a better approximation of the  effective
bulk  permeability.  The   permeability
measurements are then  compared to the
predictions of a widely used empirical
model.     Source:     1992    Toxics
Measurement Symposium.111 Author  &
EPA  Contact: Ronald B. Mosley (919-
S41-7865).

Designs for New  Residential HAC
Systems to Achieve Radon and Other
Soil Gas Reduction - Residential heating
and  cooling   (HAC)   systems  can
significantly impact the pressure-driven
entry of soil  gas into houses. Entry  of
soil gas is of  concern  because  it can
contain   contaminants such as  radon,
VOCs,  pesticides, and biocontaminants.
HAC configurations that have lowered
radon entry rate in new construction, and
which could  be applied to reduce the
entry of other soil gas contaminants, are
presented. Source:  Proceedings  of the
1993  International  Radon  Conference,
Denver,  CO., September 20-23, 1993.
Lead Author &  EPA Contact:  Timothy
M. Dyess (919-541-2802).

EPA's  Indoor  Air Quality/Pollution
Prevention  Workshop  -  To   assist
AEERL   in   prioritizing   areas    of
AQ/pollution   prevention   research,  a
workshop was held March  9-10, 1993.
 lie workshop is discussed on page  9.
Source: EP A Report (EPA-600/R-93/198;
NTIS PB94-114782) and the Proceedings
of the Annual AWMA Meeting, June 13-
18, 1993. EPA  Contact: Kelly Leovic
(919-541-7717).

Evaluation   of  Radon  Movement
Through   Soil   and  Foundation
Substructures -  A  2x2x4m chamber
filled with radium containing soil is being
used to study  convective and diffusive
soil  gas movement  through  soil  and
foundation substructures. A  perforated
pipe vacuum line draws air (or tracer gas)
through the soil under varying moisture
conditions to simulate  convective flow
conditions. Data from the chamber will
be  used  to  model  soil permeability
properties and  radon entry  conditions
imperative to site characterization for soil
gas source potential.   Source:   1992
Toxics Measurement Symposium.1" Lead
Author,  Marc  Y.  Memetrez.   EPA
Contact: Ron Mosley (919-541-7865).

Follow-up Radon Measurements in 14
Mitigated Schools - To determine the
long-term   performance  of   radon
mitigation systems, radon measurements
were made between February  and April
1992  in  14  schools  that  had  been
mitigated  between   1988 and  1991.
Results   show   that   active   soil
depressurization systems have  been very
effective in  maintaining low  long-term
radon levels in these 14 schools. Source:
EPA Report (EPA-600/R-93/197). Lead
Author,  Jean-Claude  Dehmel.   EPA
Contact: Kelly Leovic (919-541-7717).

Measurements of Soil Permeability and
Pressure  Fields  in EPA's  Soil-Gas
Chamber - An  analytic solution for
advective  flow  in  AEERL's soil-gas
chamber is  presented.   The solution
includes the effects of moisture dependent
variations of permeability with position.
Relatively good agreement between the
measurements  and  model is  obtained
except in the region near the water level
where the boundary conditions are not
rigorously satisfied. Source: Proceedings
of  the   1993   International  Radon
Conference, Denver, CO, September 20-
23, 1993 EPA Contact: Ron B. Mosley
(919-541-7865).
                                                                                      Measurement  of  the   Surface
                                                                                      Permeability of Basement Concretes -
                                                                                      This report details the development and
                                                                                      test  results of a portable permeameter
                                                                                      used   for    surface   permeability
                                                                                      measurements  of   concrete.   Surface
                                                                                      permeability of concrete  determines the
                                                                                      performance of seals between concrete
                                                                                      sections, an important passive technique
                                                                                      for  preventing radon  entry  into  new
                                                                                      buildings. EPA Report (EPA-600/R-93-
                                                                                      169; NTIS PB93-232114). Lead Author,
                                                                                      Arthur Scott.  EPA Contact: Timothy M.
                                                                                      Dyess (919-541-2802).
Radon in Florida Large Building Study
- This project is examining how IAQ is
affected  by  ventilation,   mixing,  and
leakage rates in two research buildings.
Measurements include:  radon, carbon
dioxide,   temperature,   humidity,
differential pressures, outdoor air intake
flow rates, and tracer gas methods. The
outdoor air intake is adjusted  from no
outdoor air to recommended ASHRAE
ventilation standards.  Source:    1992
Toxics   Measurement   Symposium. *
Author  &   EPA  Contact: Marc  Y.
Menetrez (919-541-7981).

Removal  Efficiencies  in  Terms  of
Particle  Size and Concentration  of
Console Air Cleaners in a Suburban
Home - Removal efficiency data and
cost/benefits for two commercial console
air  cleaners are  presented.  One   is
equipped with a high efficiency filter and
the  other with an ESP. Data show that
both units are highly efficient at removing
particles 1.0 /tin and greater,  the size
range of  spores and  pollens,  but less
efficient at removing submicron particles.
Source:   Proceedings  of   the  Annual
AWMA  meeting,  June   13-18,  1993
(EPA-600/A-93-183,   NTIS   PB93-
222016). Lead Author & EPA  Contact:
Raymond S. Steiber (919-541- 2288).

The Environmental  Resource Guide
(ERG) - The ERG is a comprehensive
reference   resource  being  developed
cooperatively between AEERL and the
American  Institute  of Architects (AIA).
The ERG aids architects and other design
professionals in evaluating environmental
impacts of design decisions. The ERG's
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 six   sections   include   case  studies,
 professional  advisories,  and technical
 analyses  of the life  cycle of building
 materials.  AEERL is involved with:  1)
 development  of the  materials  analysis
 section;  2)  development  of  a   data
 gathering/data analysis methodology (i.e.,
 modified Life Cycle Assessment); and  3)
 establishment   of  acceptable   quality
 assurance and peer review procedures.
The ERG's goal is to meet the public's
need for informed decision making  in
support  of sustainable environments.  It
also provides public outreach for two  of
EPA's   highest  priorities:  IAQ  and
pollution   prevention.    The  ERG
subscription  service  currently reaches
more  than  2000.     For  subscription
information, contact Nancy Solomon  at
AIA  (202-626-7463).  EPA   Contact:
James B. White (919-541-1189).
The Indoor Air Quality Data Station:
An  Integrated  Sensing and  Logging
Platform  -  This  portable  IAQ  data
logging system  monitors HVAC  influ-
ences on IAQ in schools and other
buildings.  Temperature, relative humid-
ity,  carbon dioxide,  radon, and  differ-
ential pressure data can be  retrieved via
modem. Source: 1992 Toxics Measure-
ment  Symposium.*   Author  &  EPA
Contact: Bruce Harris (919-541-7807).
                                           EASE ~ Building Asaeaamett airiSurvey
                                            ,   Evaluation        :        '!'
AEERL - Air and Energy Engineering: Research
AIA - American Institute of ArcMtoctg
AREAL * Atmospheric Research ud Exposure
    Assessment Laboratory
ASHRAE - American Society of Heating.
   RefrigerttisB & AiiMConditioamg Engineer*
ASTM - American Society of Testing and
   Materials
AWMA - Air and Waste Management Association

Mailing List for Inside IAQ
If you would like to be added to or deleted from the  Inside IAQ mailing list,
please mail or fax (919-541-2157) your name and address to:
   Inside IAQ, Attn: Kelly Leovic
   U.S. EPA/AEERL MD-54
   Research Triangle Park, NC 27711
                                            1   Laboratory
                                           ECAO - Enviroamemal Criteria ««I AMesement
                                                                       '
                                           HAC - Heating and/or Cooling
                                           HERL- Health Effect* Research Laboratory
                                           HVAC - Heating, Vemilating and
iMSL - Environmental 1
    Laboratory
EPA - IT.S. Environmental Protection Agency
ERG -Environmental Re«cK>rc« Guide
ISP - ElectawtaBc Precqiitator
ETS > Environmental Tobacco Smoke
GCVMS -
IAQ -Indoor Air Qu,lily
NTIS . National Ttchaica
ORO . Office of Reaeareh and Development
PAH - Polycyclk Aromatic Hydrocarbon
PCR - Polymeraae Chain Reaction
PMN - Pdytnorj)ho«ielear Neutropha*
$VOC * Semivolatile Organic Cbropouwt
TVW - Tottl Volatil* Organic Compound
VOC - Volatile Organic Compound
                     IAQ Information Clearinghouse

                     Additional information on indoor air is available through the Indoor Air
                     Quality Information Clearinghouse maintained by EPA's Indoor Air Division.
                     The Clearinghouse can be contacted by phone at 1-800-438-4318 or 301-585-
                     9020, or by (x at 301-588-3408.
        &U.S. GOVERNMENT PRINTING OFFICE: 19«4 - 550-067/KOI43
               Page 14

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