Office of Pollution
                                       Prevention and
                United States             Toxics
                Environmental            Washington, DC        June 1999
                     TOXICS RELEASE INVENTORY
        ERr\    List f Toxic Chemicals within the Nicotine and Salts
                     Category
       Section 313 of EPCRA requires certain facilities manufacturing, processing, or otherwise
using listed toxic chemicals to report their environmental releases of such chemicals annually.
Beginning with the 1991 reporting year, such facilities also must report pollution prevention and
recycling data for such chemicals, pursuant to section 6607 of the Pollution Prevention Act, 42
U.S.C. 13106.  When enacted, Section 313 established an initial list of toxic chemicals that was
comprised of more than 300 chemicals and 20 chemical categories. Section 313(d) authorizes
EPA to add chemicals to or delete chemicals from the list, and sets  forth criteria for these actions.
                                    CONTENTS

Section 1. Introduction	2

Section 2. CAS Number List of Chemicals within the Nicotine and Salts Category  	4

Section 3. CAS Number List of Mixtures within the Nicotine and Salts Category	14

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                                 Section 1. Introduction
       On November 30, 1994 EPA added 286 chemicals and chemical categories to the list of
toxic chemicals under Section 313 of the Emergency Planning and Community Right-to-Know
Act of 1986 (EPCRA), 42 U.S.C. 11001 et seq. These additions are described at 59 FR 61432,
and are effective January 1, 1995 for reports due July 1, 1996. Six chemical categories (nicotine
and salts, strychnine and salts, polychlorinated alkanes, polycyclic aromatic compounds, water
dissociable nitrate compounds, and diisocyanates) are included in these additions.  At the time of
the addition, EPA indicated that the Agency would work with the public and the regulated
community to develop, as appropriate, interpretations and guidance that the Agency determines
are necessary to facilitate accurate reporting for these categories.  This document constitutes such
guidance for the nicotine and salts category.

       EPCRA Section 313 requires threshold determinations for chemical categories to be
based on the total of all chemicals in the category manufactured, processed, or otherwise used.
For example, a facility that manufactures three members of a chemical category would count the
total amount of all three  chemicals manufactured towards the manufacturing threshold for that
category. When filing reports for chemical categories, the releases are determined in the same
manner as the thresholds. One report  is filed for the category and all releases are reported on this
form.

       The nicotine and salts category is subject to the one percent de minimis concentration.
Thus, mixtures that contain members of this category at concentrations equal to or in excess of
one percent should be factored into threshold and release determinations.

       Any compound that has a nicotine or a nicotine salt component is reportable. EPA is
providing the following list of CAS numbers and chemical names to aid the regulated community
in determining whether they need to report for the nicotine and salts category. However, this list
is not  exhaustive. If a facility is manufacturing, processing, or using a chemical that has a
nicotine or a nicotine salt component,  they must report to TRI, even if this chemical does not
appear on the following list.

Who Must Report

       A plant, factory,  or other facility is subject to the provisions of Section 313, if it meets all
three of the following criteria:

             It is included in a covered Standard Industrial Classification (SIC) code as listed
             in the following table;  and

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Manufacturing
Metal mining
Coal Mining
Electrical utilities
Treatment, Storage, and Disposal facilities
Solvent recovery services
Chemical distributors
Petroleum bulk terminals
20-39
10 (except 1011, 1081, and 1094)
12 (except 12411)
4911, 4931, and 4939, limited to facilities that combust coal
and/or oil for the purpose of generating electricity for
distribution in commerce
4953, limited to RCRA Subtitle C permitted or interim status
facilities
7389, limited to facilities primarily engaged in solvent
recovery services on a contract or fee basis
5169
5171
              It has 10 or more full-time employees (or the equivalent 20,000 hours per year);
              and

              It manufactures, imports, processes, or otherwise uses any (if the toxic chemicals
              listed on the EPCRA Section 313 list in amounts greater than the "threshold"
              quantities specified below.
Thresholds
       Thresholds are specified amounts of toxic chemicals used during the calendar year that
trigger reporting requirements.

       If a facility manufactures or imports any of the listed toxic chemicals, the threshold
quantity will be:

             25,000 pounds per toxic chemical or category over the calendar year.

       If a facility processes any of the listed toxic chemicals, the threshold quantity will be:

             25,000 pounds per toxic chemical or category over the calendar year.

       If a facility otherwise uses any of the listed toxic chemicals (without incorporating it into
any product or producing it at the facility), the threshold quantity is:
              10,000 pounds per toxic chemical or category over the calendar year.

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     Section 2. CAS Number List of Chemicals within the Nicotine and Salts Category
       EPA is providing the following list of CAS numbers and chemical names to aid the
regulated community in determining whether they need to report for the nicotine and salts
category. However, this list is not exhaustive.  If a facility is manufacturing, processing, or using
a chemical that has a nicotine or a nicotine salt component,  they must report to TRI, even if this
chemical does not appear on the following list.
Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Pyridine, 3-( 1 -methyl-2-pyrrolidinyl)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, sulfate (2:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-
dihydroxybutanedioate (1:2)
Silicate(2-), hexafluoro-, dihydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:2)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [S-(R*,R*)]-2,3-
dihydroxybutanedioate (1:2)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, hyrochloride, (S)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-
dihyroxybutanedioate
Formic acid, compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
(2:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, triacetate
Propanoic acid, compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
(3:1)
Butanoic acid, compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
(3:1)
Nicotine, triisobutyrate
Butanoic acid, 3-methyl-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
Nicotine, monoacetate
Phenol, 2,4-dinitro-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
[l,l'-Biphenyl]-3-carboxylic acid, 2-hydroxy-, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Other Name(s)
Nicotine
Nicotine, sulfate (2:1);
Black Leaf 40
Nicotine, tartrate (1 :2);
Nicotine acid tartrate
Nicotine,
Hexafluorosilicate(2-) (2:1)
Nicotine, D-tartrate
Nicotine, hydrochloride
Nicotine, tartrate
Nicotine, diformate
Nicotine, triacetate
Nicotine, tripropionate
Nicotine, tributyrate

Nicotine, isovalerate (1:3)

Nicotine dinitrophenolate

CAS Number
54-11-5
65-30-5
65-31-6
653-81-6
1421-32-5
2820-51-1
3275-73-8
4699-61-0
4699-62-1
4699-63-2
4699-64-3
4699-65-4
4777-37-1
5153-64-0
5308-71-4
5456-02-0

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Nicotine, (2,4-dintrophenyl)acetate (1:3)
Benzole acid, 2,5-dihydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with 2,4,6-
trinitrophenol (1:2)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, dihydrochloride, (S)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, monohydriodide, (S)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, dihydriodide, (S)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-
dihydroxybutanedioate (1:2), dihydrate
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with 2,4-
dihydro-5-methyl-4-nitro-2-(4-nitrophenyl)-3H-pyrazol-3-one (1:1)
Aurate(l-), tetrachloro-, (SP-4-1)-, hydrogen, compound with (S)-3-
( l-methyl-2-pyrrolidinyl)pyridine (2:1)
1,2-Benzenedicarboxylic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyOpyridine
Zincate(2-), (T-4)-, dihydrogen, compound with (S)-2-(l-methyl-2-
pyrrolidinyl)pyridine (1:1), monohydrate
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with 2,4-
dihydro-5-methyl-4-nitro-2-(4-nitrophenyl)-3H-pyrazol-3-one (1:2)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, sulfate
Hydrogen triiodide, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridinehydrochloride (1:1:1)
Nicotine, compound with 2,4-dinitro-l-naphthol (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-
dihydroxybutanedioate (1:1)
Hydrogen triiodide, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Benzoic acid, 3,4,5-trihydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
Nicotine, l-hydroxy-2-naphthoate
Tungstate(4-), [orthosilicato(4-)]hexatriacontaoxododeca-,
tetrahydrogen, compound with (S)-2-(l-methyl-2-
pyrrolidinyl)pyridine (1:2)
Other Name(s)
Nicotine, tris[(2,4-
dinitrophenyl)acetate]
Gentisic acid, compound with
nicotine (1:1)
Nicotine, dipicrate
Nicotine dihydrochloride
Nicotine hydroiodide
Nicotine dihydriodide
Nicotine, tartrate (1:2), dihydrate
Nicotine, picrolonate
Nicotine, bis[tetrachloroaurate
(1-)]; Nicotine aurichloride
Nicotine, phthalate
Nicotine, tetrachlorozincate (2-),
monohydrate; Nicotine zinc
chloride double salt
Nicotine, dipicrolonate
Nicotine, sulfate
Nicotine hydrochloride
hydriodide iodine

Nicotine, tartrate (1:1)
Hydriodic acid, compound with
nicotine and!2 (1:1:1)
Nicotine, gallate

Silicic acid (H4SiO4), tungsten
complex, compound with
nicotine
CAS Number
5562-64-1
6012-21-1
6012-23-3
6019-02-9
6019-03-0
6019-04-1
6019-06-3
6019-09-6
6059-25-2
6159-83-7
6169-10-4
6191-53-3
6505-86-8
6509-46-2
6549-06-0
6550-19-2
6591-68-0
10020-05-0
10047-35-5
12328-53-9

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Nicotine, mono(dimethyldithiocarbamate)
Nicotine, mono(methyldithiocarbamate)
Nicotine, mono(tetrathio-p-benzenedicarbamate)
Nicotine, mono(dithiocarbanilate)
Nicotine, 1 ,4-piperazinedicarbodithiote (1:1)
Nicotine, mono(dithiocarbazate)
Nicotine, compound with aluminum bromide
Nicotine, compound with aluminum chloride
Nicotine, compound within antimony chloride (SbCl5)
Nicotine, compound with zinc chloride
Nicotine, compound with cadmium chloride
Nicotine, compound with dichloroethylaluminum
Nicotine, compound with triethylaluminum
Nicotine, compound with chlorodiethylaluminum
Nicotine, compound with diethylzinc
Nicotine, compound with mercury chloride (HgCl2)
Nicotine, compound with antimony chloride
Nicotine, compound with aluminum iodide
Nicotine, compound with iron chloride (FeCl3)
Propanoic acid, 2-hydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Nicotine, ethylenebis[dithiocarbamate] (1:1)
Nicotine, compound with bis[2-
[(dithiocarboxy)amino]ethyl]dithiocarbamic acid (1:1)
Lactic acid, compound with nicotine
Zincate(2-), [.mu.-[ethanedioato(2-)-O,O'":O',O"]]
bis[ethanedioato(2-)-O,O']di, dihydrogen, compound with (S)-
3-( 1 -methy l-2-pyrrolidinyl)pyridine (1:1)
Benzoic acid, 3,4,5-trihydroxy-, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-rnethyl-2-pyrrolidinyl)-, (S)-, ethanedioate (1:2)
Other Name(s)



















Lactic acid, compound
with nicotine (1:1)


Nicotine, lactate

Nicotine, monogallate
Nicotine, oxalate (1:2)
CAS Number
13624-74-3
13624-75-4
13624-76-5
13624-77-6
13624-78-7
13624-79-8
13837-13-3
13837-14-4
13890-80-7
13890-83-0
13890-84-1
13890-85-2
13890-86-3
13890-87-4
13890-88-5
14032-92-9
14129-12-5
14129-13-6
14222-24-3
14474-00-1
14480-51-4
14544-85-5
15197-02-1
15375-89-0
15566-33-3
15566-45-7

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Nicotine, tris(p-nitrobenzoate)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound
with 2,4,6-trinitrophenol
Nicotine, di(hydriodide-d)
Manganate(l-), tris(salicylato)-, hydrogen, compound
with nicotine and salicylic acid (1 :2: 1)
Nicotine, compound with zinc hexafluorosilicate(2-)
(1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, conjugate
monoacid, (S)-
Nicotine, mono(4-aminosalicylate)
Nicotine, monohydrochloride, compound with iodine
chloride (IC1) (1:1)
Pyridine, 3-( 1 -methyl-2-pyrrolidinyl)-,
monohydrochloride (S)-
Propanoic acid, 2,2-dimethyl-, compound with (S)-3-
( 1 -methyl-2-pyrrolidiny l)pyridine (1:1)
Pyridine, 3-(l -methyl-2-pyrrolidinyl)-, (S)-, compound
with iodomethane (1:1)
Nicotine, monoethiodide
Pyridine, 3-(l -methyl-2-pyrrolidinyl)-, (S)-,
ethanedioate
Nicotine, gentisate
Nicotine, pivalate
Nicotine, compound with 4-(l-cyclohexylpentyl)-2,6-
dinitrophenol (1:1)
Nicotine, compound with .alpha.-(3,5-dibromo-4-
hydroxyphenyl)-.alpha.-(3,5-dibromo-4-oxo-2,5-
cyclohexadien-l-ylidene)-o-toluenesulfonic acid (1:2)
2-Propenoic acid, 2-methyl-, homopolymer, compound
with (S)-3-( 1 -methyl-2-pyrrolidinyl)pyridine
Other Name(s)
Benzoic acid, p-nitro-, compound
with nicotine (3:1)
Nicotine, picrate
Hydriodic acid-d, compound with
nicotine (2:1)


Nicotine, conjugate monoacid
Salicylic acid, 4-amino-,
compound with nicotine (1:1)
Nicotine chloriodide,
hydrochloride
Nicotine, monohydrochloride
Nicotine, monopivalate; Pivalic
acid nicotine salt
Nicotine, monomethiodide
Nicotine ethiodide
Nicotine, oxalate
Nicotine gentisic acid salt



Methacrylic acid, polymers,
compound with nicotine;
Poly(methacrylic acid)nicotine salt
CAS Number
15677-87-9
16426-45-2
16488-84-9
18911-12-1
19333-07-4
19527-02-7
20334-41-2
20539-51-9
21361-93-3
21583-33-5
22083-76-7
23277-52-3
23758-42-1
23758-43-2
24580-89-0
25137-75-1
25221-70-9
26793-60-2

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Categroy
Collective Index Name
2-Propenoic acid, 2-methyl-, homopolymer,
isotactic, compound with (S)-3-(l-methyl-2-
pyrrolidinyOpyridine
Nicotine,
diamminetetf akis(isothiocy anato)chromate( 1 -)
Benzoic acid, 2-hydroxy-, compound with (S)-3-
(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Nicotine, privalate (1:2)
Chromate( 1 -), diamminetetrakis(thiocyanato-N)-,
(OC-6-1 1)-, hydrogen, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Alginic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
Pectin, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
Phenol, pentachloro-, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (2:1)
Pyridine, 3-( 1 -methyl-2-pyrrolidinyl)-,
monohydriodide, monohydrochloride,(S)-
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [R-
(R*,R*)]-2,3-dihydroxybutanedioate (2:1)
Cuprate(2-), tetrachloro-, (T-4)-, dihydrogen,
compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l -methyl-2-pyrrolidinyl)-, (S)-,
(R*,R*)-(.+-.)-2,3-dihyroxybutanedioate(l:l)
Benzenesulfonic acid, 4-[[4-
(dimethylamino)phenyl]azo]-, sodium salt,
compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Zincate(2-), tetrachloro-, (T-4)-, dihydrogen,
compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Chromate(l-), bis(4-
ethylbenzenamine)tetrakis(thiocyanato-N)-, (OC-
6-1 1)-, hydrogen, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Other Name(s)
Methacrylic acid, polymers, isotactic,
compound with nicotine; Isotactic
poly(methacrylic acid) nicotine salt
Chromate(l-), diamminetetrakis
(isothiocyanato) -, hydrogen, compound
with nicotine
Nicotine, monosalicylate; Salicylic acid,
compound with nicotine (1:1); Eudermol


Pyridine, 3-(l -methyl-2-pyrrolidinyl)-, (S)-
, alginate; Nicotine alginate
Nicotine pectate
Nicotine pentachlorophenolate



Nicotine hydrogen (.+-.) tartrate
Nicotine compound with methyl orange
(1:1); Nicotine-methyl orange complex
(1:1)

Benzenamine, 4-ethyl-, chromium
complex, compound with nicotine
CAS Number
26793-61-3
27399-23-1
29790-52-1
31269-83-7
36447-36-6
39461-16-0
39461-17-1
41944-89-2
46002-56-6
51385-03-6
53224-08-1
54661-91-5
55774-24-8
55990-77-7
56110-75-9

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Listing by CAS Number of Each Individual chemical within the Nicotine and Salts Category
Collective Index Name
Hydrochloric acid-d, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
.beta.-Cyclodextrin, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Chromate( 1 -), bis(4-methoxybenzenamine-
N)tetrakis(thiocyanato-N)-,(OC-6-l 1)-, hydrogen, compound
with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Chromate( 1 -), bis(4-ethoxybenzenamine-
N)tetrakis(thiocyanato-N)-, (OC-6-11)-, hydrogen, compound
with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Chromate( 1 -), bis(benzenemethanarnine)tetrakis(thiocyanato-
N>, (OC-6-1 1)-, hydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Chromate(l-), bis(benzenamine)tetrakis(thiocyanato-N)-,
hydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyOpyridine (1:1)
Chromate(l-), bis(pyridine)tetrakis(thiocyanato-N)-, (OC-6-
12)-, hydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Chromate( 1 -), bis(4-methylbenzenamine)tetrakis
(thiocyanato-N)- (OC-6-1 1)-, hydrogen, compund with (S)-3-
( 1 -methyl-2-pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, diperchlorate
Chromate( 1 -), bis(4-methyl- 1 ,3-benzenediamine-
Nl)tetrakis(thiocyanato-N)-,(OC-6-ll)-, hydrogen, compound
with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Chromate(l-), bis(2-methyl-l ,4-benzenediamine-
N4)tetrakis(thiocyanato-N)-,(OC-6-ll)-, hydrogen, compound
with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Cuprate(2-), tetrachloro-, dihydrogen, compound with (S)-3-
( 1 -methyl-2-pyrrolidiny l)pyridine (1:1)
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-
hydroxyethyl)-4-methyl- chloride, monohydrochloride,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine sulfate
(2:2:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, ethanedioate (2:1)
Chromate(l-), bis(l-butanamine)tetrakis(thicyanato-N)-, (OC-
6-1 1)-, hydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Other Name(s)
Pyridine,3-( 1 -methyl- 2-pyrrolidinyl)-,
mono(hydrochloride-d), (S)-

Benzenamine, 4-methoxy-, chromium
complex, compound with nicotine
Benzeamine, 4-ethoxy-, chromium
complex, compound with nicotine
Benzenemethanamine, chromium
complex, compound with nicotine


Benzenamine, 4-methyl-, chromium
complex, compound with nicotine

1 ,3-Benzenediamine, 4-methyl-,
chormium complex, compound with
nicotine
1 ,4-Benzenediamine, 2-methyl-,
chromium complex, compound with
nicotine



1-Butanamine, chromium complex,
compound with nicotine
CAS Number
58787-03-4
58947-99-2
59598-67-3
59598-68-4
59598-69-5
59598-70-8
59598-84-4
59599-00-7
59888-66-3
60004-81-1
60065-70-5
61091-23-4
61566-91-4
62201-70-1
66915-36-4
9

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Chromate(l-), bis(l-propanamine)tetrakis(thiocyanato-N)-, (OC-
6-11)-, hydrogen, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [S-(R*,R*)]-,
compound with (S)-3-(l -methyl- 2-pyrrolidinyl)pyridine (1:1)
Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [R-(R*,R*)]-,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, 2-hydroxy- 1,2,3-
propanetricarboxylate (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, phosphate (1:1)
Butanedioic acid, hydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, 2-hydroxy- 1,2,3-
propanetricarboxylate
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, phospate
Butanedioic acid, hydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
Butanoic acid, 2-methyl-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
Hexadecanoic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, 2-hydroxy- 1,2,3-
propanetricarboxylate (1:2)
Butanedioic acid, hydroxy-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (2:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, monobenzoate
Benzeneacetic acid compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
1 ,2-Benzenedicarboxylic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Propanoic acid, 2-oxo-, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Glutamic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Aspartic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Other Name(s)
1-Propanamine,
chromium complex,
compound with nicotine




Nicotine, malate (1:1)







Benzoic acid, compound
with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
(1:1)





CAS Number
66915-45-5
68935-25-1
68935-26-2
72057-10-4
72057-11-5
73057-36-0
73086-01-8
73086-02-9
73086-03-0
88660-49-5
88660-50-8
88660-51-9
88660-52-0
88660-53-1
88660-54-2
88660-55-3
88660-56-4
88660-57-5
88660-58-6
10

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Benzoic acid, 2-hydroxy-5-sulfo-, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, pectate
Platinate(2-), hexachloro-, (OC-6-1 1)-, dihydrogen,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Tungstate(4-), [.mu.l2-[orthosilicateo(4-)-
O:O:O:O1:O':O':O":O":O":O"':O'":O'"]]tetracosa-.mu.-
oxododecaoxododeca-, tetrahydrogen, compound with (S)-3-
(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Pentanoic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
Dodecanoic acid, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (3:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with
cellulose carboxymethyl ether
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with
cellulose carboxymethyl 2-hydroxypropyl ether
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with
cellulose dihydrogen phosphate
2-Propenoic acid, homopolymer, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine
Cellulose, 4-carboxybutyl ether, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine
Alginic acid, phosphate, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, 2-hydroxy- 1,2,3-
propanetricarboxylate (2: 1 )
2-Propenoic acid, 2-methyl-, polymer with diethenylbenzene,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
Nicotine, compound with AcOH and Hg(OAc)2
Phenol, 2,2'-sulfinyl bis 4-6-dichloro-, compound with
nicotine
Platinate(2-), tetrachloro-, (SP-4-1)-, dipotassium, polymer
with (S)-3-( 1 -methyl-2-pyrrolidinyl)pyridine
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, compound with
molybdenum hydroxide oxide phosphate (1:1)
Benzoic acid, p-acetamido, compound with nicotine
Other Name(s)

Pectic acid, compound with (S)-3-
( 1 -methyl-2-pyrrolidinyl)pyridine

Silicic acid (H4SiO4), tungsten
complex, compound with nicotine








Nicotine, citrate (2:1)56X
Nicotine polacrilex





CAS Number
88660-59-7
88660-60-0
88660-62-2
88660-63-3
88673-56-7
88673-57-8
90937-10-3
90937-12-5
90937-13-6
90960-67-1
91098-28-1
91198-78-6
94006-00-5
96055-45-7
100022-25-1
100435-91-4
102857-74-9
104062-50-2
110441-65-1
11

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Chromic acid (H2Cr2O7), compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine (1:1)
Benzhydrol, 4,4'-dichloro-.alpha.-(dichloromethyl)-, compound
with nicotine
Nicotine, malate (2:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, conjugate diacid, (S)-
Quinolinium, l-ethyl-4-[2-(2-hydroxyphenyl)ethenyl]-, iodide,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Quinolinium, 2-[2-(2,4-dihydroxyphenyl)ethenyl]-l-ethyl-,
iodide, compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
(1:1)
Quinolinium, l-ethyl-2-[2-(4-hydroxyphenyl)ethenyl]-, iodide,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Quinolinium, l-ethyl-2-[2-(2-hydroxyphenyl)ethenyl]-, iodide,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
Pyridinium, l-ethyl-2-[2-(2-hydroxyphenyl)ethenyl]-, iodide,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
l,3,5-Triazine-2,4,6(lH,3H,5H)-trione, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine
2,4-Hexadiyne-l,6-diol, 1,1,6,6-tetraphenyl-, compound with
(S)-3-( 1 -methy l-2-pyrrolidinyl)pyridine (1:1)
Nicotine, bromocadmate
Nicotine, iodocadmate
Nicotine, tetraiodocadmate
Nicotine, tetrabromocadmate
Nicotine, Fe complex
Nicotine, pentachloroferrate
Nicotine, Fe complex
Nicotine, Fe complex
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, monohydrate, (S)-
2,5-Cyclohexadiene-l,4-dione, 2,3,5,6-tetrachloro-, compound
with (S)-3-(l-methyl-2-pyrroldinyl)pyridine (1:1)
Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, [S-(R*,R*)]-2,3-
dihydroxybutanedioate (1:1)
Other Name(s)















Nicotine pentaiodoferrate

Nicotine
pentabromoferrate
Nicotine tetraiodoferrate
Nicotine monohydrate


CAS Number
110794-22-4
118980-02-2
119328-39-1
119427-28-0
119543-59-8
119543-61-2
119543-62-3
119543-63-4
119543-64-5
122759-59-5
125947-48-0
126425-22-7
126425-23-8
12640-15-7
126460-16-0
126460-19-3
126460-20-6
126505-90-6
127088-40-8
128758-70-3
129047-75-2
129721-88-6
12

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Listing by CAS Number of Each Individual Chemical within the Nicotine and Salts Category
Collective Index Name
Tungstate(S-), tetracosa-.mu.-oxododecaoxo[.mu. 1 2-
[tetrahydroxyborato(5-)-
O:O:O:O'-O'-O'-O":O":O":O'":O'":O'"]]dodeca-, pentahydrogen,
compound with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:4)
.beta.-Cyclodextrin, compound with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine
4,6:9,12:22,24:27,30-Tetraetheno-15,18,21:33,3,36-
diethenylylidenedibenzo[k,al ] [1,8,1 7,24]tetraoxacyclodotriacon
tin-l,2,19,20-tetracarboxylic acid, 3,8,13,18a,21,26,31,36a-
octahydro-ion(3-), [3S-(3R*,18aR*,21R*,36aR*)]-, compound
with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine (1:1)
4,6:9,12:22,24:27,30-Tetraetheno-15,18,21:33,3,36-
diethenylylidenedibenzo
[k,al ] [ 1 ,8, 1 7,24]tetraoxacyclodotriacontin- 1 ,2, 1 9,20-
tetracarboxylic acid, 3,8,13,18a,21,26,31,36a-octahydro-ion
(3-), [3R-(3R*,18aR*,21R*,36aR*)]-, compound with (S)-3-(l-
methyl-2-pyrrolidinyl)pyridine (1:1)
Other Name(s)
Borate(l-), tetrahydroxy-,
tungsten complex,
compound with nicotine



CAS Number
130555-55-4
137740-94-4
151527-31-0
151528-73-3
13

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      Section 3. CAS Number List of Mixtures within the Nicotine and Salts Category
        EPA is providing the following list of CAS numbers and chemical names for mixtures
that contain a nicotine or a nicotine salt component.  This list will aid the regulated community in
determining whether they need to report for the nicotine and salts category.  However, this list is
not exhaustive. If a facility is manufacturing, processing, or using a mixture that contains a
nicotine or a nicotine salt component, they must report to TRI, even if this chemical does not
appear on the following list. Threshold calculations for the nicotine and salts category should
account only for the percentage of the nicotine or the nicotine salt component contained in the
mixture.
                             Mixtures Containing Nicotine or Nicotine Salts
                        Mixture Name
    Nicotine
   Component
Mixture CAS
  Number
 Sulfuric acid copper(2+) salt (1:1), mixture with arsenic acid
 (H3AsO4) copper(2+) salt, (S)-3-(l-methyl-2-pyrrolidinyl)pyridine
 and tetrachloromethane
Nicotine
54-11-5
  8065-25-6
 Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, mixture with 1,1'-(2,2,2-
 trichloroethylidene)bis[4-chlorobenzene]
Nicotine
54-11-5
  8074-22-4
 Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, mixture with barium
 sulfide (BaS) and sulfur
Nicotine
54-11-5
  8077-43-8
 Benzoic acid, 3,4,5-trihydroxy-, compound with (S)-3-(l-methyl-2-
 pyrrolidinyl)pyridine (1:1), mixture with manganese chloride
 (MnCl2)
Nicotine
Monogallate
15566-33-3
 55874-21-0
 Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-nitrophenyl)
 ester, mixture with (S)-3-(l-methyl-2-pyrrolidinyl)pyridine sulfate
 (2:1)
Nicotine
Sulfate(2:l)
65-30-5
 97268-83-2
 Phosphoric acid, dimethyl l-methyl-3-(methylamino)-3-oxo-l-
 propenyl ester, (E)-, mixture with (S)-3-(l-methyl-2-
 pyrrolidinyl)pyridine sulfate (2:1)
Nicotine
Sulfate(2:l)
65-30-5
 97268-84-3
 Pyridine, 3-(l-methyl-2-pyrrolidinyl)-, (S)-, mixture with (S)-3-(l-
 methyl-2-pyrrolidinyl)pyridine[R-(R*,R*)]-2,3-
 dihydroxybutanedioate (1:2)
Nicotine
54-11-5;
Nicotine Tartrate
(1:2)
65-31-6
 126898-17-7
 Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-,
 (5.alpha.,6.alpha.,14.alpha.)-, mixture with
 (5.alpha.,6.alpha.,14.alpha.)-7,8-didehydro-4,5-epoxy-3-methoxy-
 17-methylmorphinan-6-ol, l-[(3,4-dimethoxyphenyl)methyl]-6,7-
 dimethoxyisoquinoline,[7(S)-
 (l.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)]-9-methyl-3-oxa-9-
 azatricyclo[3.3.1.02,4]non-7-yl .alpha. -
 (hydroxymethyl)benzeneacetate and (S)-3-(l-methyl-2-
 pyrrolidinyl)pyridine	
Nicotine
54-11-5
 127060-78-0
                                                 14

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Mixtures Containing Nicotine or Nicotine Salts
Mixture Name
Phenol, 4-chloro-3,5-dimethyl-, mixture with 3,6-dichloropyridazine
and (S)-3-( 1 -methyl-2-pyrrolidinyl)pyridine
2-Pyrrolidinone, l-methyl-5-(3-pyridinyl)-, (S)-, mixture with (S)-3-
( 1 -methyl-2-pyrrolidinyl)pyridine
lH-Pyrazole-5-carboxamide, 4-chloro-N-[[4-(l,l-
dimethylethyl)phenyl]methyl]-3-ethyl-l-methyl-, mixture with (S)-3-
(l-methyl-2-pyrrolidinyl)pyridine sulfate (2:1)
Benzoic acid, 3,5-dimethyl-, l-(l,l-dimethylethyl)-2-(4-
ethylbenzoyl)hydrazide, mixture with (S)-3-(l-methyl-2-
pyrrolidinyl)pyridine sulfate (2:1)
Nicotine
Component
Nicotine
54-11-5
Nicotine
54-11-5
Nicotine
Sulfate(2:l)
65-30-5
Nicotine
Sulfate(2:l)
65-30-5
Mixture CAS
Number
143222-98-4
146081-02-9
147762-42-3
149294-95-1
15

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