6.
                                           SEPTEMBER 1983



                                            STATUS REPORT


                                                 on



                         REBUTTABLE  PRESUMPTION AGAINST  REGISTRATION  (RPAR) OR

                                        SPECIAL REVIEW PROCESS




                                        REGISTRATION STANDARDS



                                                  and



                                      THE DATA CALL IN  PROGRAMS
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OFFICE OF PESTICIDE PROGRAMS (TS-767C)



U. S. ENVIRONMENTAL PROTECTION AGENCY



        401 M. STREET, S. W.



       WASHINGTON, D.C.  20460
              
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                              TABLE OF CONTENTS
RPAR1 s Issued	1

PRE-RPAR Review	5

Final Actions (Voluntary Cancellations)	 6

Notice of Intent to Cancel/Suspend	 8

Notice of Intent to Register (Returned to Registration Div.)	10

RPAR' s Completed	16

Registration Standards Development - Data Collection	25

Registration Standards Development - Data Evaluation and
Development of Regulatory Position	27

Registration Standards Issued  	30

Data Call In	37

Index of Chemicals Included in Status report	46
                                                          Prepared by
                                                          Registration Support and
                                                          Emergency Response Branch
                                                          Registration Division
                                                          (703) 557-7700

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                              REGISTRATION DIVISION
DIRECTOR

DEPUTY DIRECTOR

Insecticide-Rodent icicle
     Branch

Fungicide-Herbicide
     Branch

Disinfectants Branch

Special Review Branch

Registration Support and
 Emergency Response Branch

DATA CALL IN PROGRAM (PM 51)

PM 12,  Jay Ellenberger

PM 15,  George LaRocca

PM 16,  William Miller

PM 17,  Timothy Gardner

PM 21,  Henry Jacoby

PM 23,  Richard Mountfort

PM 25,  Robert Taylor

PM 31,  John Lee

PM 32,  Arturo Castillo
Douglas D. Campt

Robert V. Brown

Herbert Harrison


James Akerman


Juanita Wills

Paul Lapsley

Ferial Bishop


Geraldine Werdig
(703)  557-7760

(703)  557-7760

(703)  557-2200


(703)  557-1650


(703)  557-3661

(703)  557-7420

(703)  557-7700
(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)
557-7436

557-2386

557-2400

557-2600

557-2690

557-1900

557-1830

557-1800

557-3675

557-3965

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                                             PREFACE

This publication contains: 1) an alphabetical listing of all chemicals which have been, or are
being, handled under the Rebuttable Presumption Against Registration [RPAR] process, (revisions
to the process and name change to Special Review are planned), 2) an alphabetical listing of the
chemicals which have been through or are now active in the Registration Standard development
process, and 3) identification by cluster of the chemicals which have been through or are being
processed in the Data Call-in program.  These processes are managed by the Registration Division,
Office of Pesticide Programs, Office of Pesticides and Toxic Substances, EPA.

This listing is intended for internal use and is updated semi-annually.  Users of this
document are encouraged to contact the appropriate PM or Branch Chief, as noted, if they have
any questions or corrections regarding the entries in this listing.

Sections of the law referred to in this document are from the Federal Insecticide,
Fungicide and Rodenticide Act (FIFRA) as amended 7 U.S.C. Section 136a(c)(2)(B).

All chemicals are listed by the names under which they were or are being reviewed. Other widely
used common or chemical names may also appear in the Index.

Copies of most of the position documents (PD) and Registration Standards are available from the
National Technical Information Service (NTIS), U.S. Department of Commerce, 5285 Port Royal Road,
Springfield, Virginia, 22161 (703) 487-4600.  The accession number and costs for paper copy
and/or microfiche are cited for those documents presently available from NTIS.

When requesting documents from the NTIS, state the name of the document, the NTIS
Accession Number, enclose proper payment (check payable to NTIS) and provide a return
mailing address.

                                     RPAR PROCESS *

Definitions of the risk criteria that, when met or exceeded, can trigger RPAR analyses,
can be found in the Federal Register of July 3, 1975 (40 CFR 162.11).  These risk criteria
are concerned with the following areas:

      1.  Acute Toxicity

      2.  Chronic Toxicity
          A.  Oncogenic
          B.  Mutagenic

* This process is undergoing revision via rulemaking and a
  name change to "Special Review Process" is contemplated.

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3.  Other Chronic Effects
    A.  Reproductive
   (1)  Fetotoxicity
   (2)  Teratogenicity
        B.  Spermatogenicity
        C.  Testicular Effects
        D.  Neurotoxicity
        E.  Others

4.  Significant reduction in wildlife, reduction in endangered species, and reduction in
    nontarget species.

5.  Lack of emergency treatment or antidote.

                                    RPAR CATEGORIES

The name of this process will be changed from "RPAR" to "Special Review" pursuant to the new
regulations which are planned for proposal in the near future.  That is why for purposes of this
report the terms may be used interchangeably.  This report is divided into a number of categories
to enable the reader to conveniently determine the current status of a particular pesticide.

Pre-RPAR — This is the initial risk investigation phase that involves an intensive review of
the scientific studies of the chemical in question that suggest that the RPAR criteria may have
been exceeded.  A validation of these studies of the chemical in question is conducted by Agency
scientists.  During this period, the registrants of the pesticide are informed of the review and
are often requested to submit additional information.  If "trigger studies" are found to be
valid, an effort is made to gather and preliminarily assess available information on the exposure
to the pesticide.  If such data are not available, the Agericy extrapolates from models or analogs
and develops exposure assumptions to hypothesize the potential risk of the pesticide under
review.  Major "trigger studies" undergo peer review (in accordance with Section 25e of FIFRA)
to confirm the EPA validation.  Discussions are held with registrants and other interested
parties in an attempt to reduce exposure to acceptable levels.  If the risk is reduced, or is
found through review to be acceptable, the RPAR review is terminated.

If risk is determined to be unacceptable, the validation of the "trigger studies" and the
combination of this hazard information with the exposure analysis produce the Agency's
preliminary position on the potential risk of the pesticide.  The document describing this
position on risk is referred to as position document one (PD 1).  Upon approval by the Agency, a
notice of the availability of the PD 1 along with a formal Notice of Rebuttable Presumption
Against Registration is published in the Federal Register.
                                             11

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Issuance of an RPAR—After a PD 1 is published, a 45 day period is allowed for comment
on the presumptions against registration presented in PD 1.  A 60 day extension is granted,
if justified.  Therefore, there is typically a 105 day period within which the Agency's
presumptions may be rebutted.

Risks may be rebutted by interested parties submitting to the Agency: (1) proof that the
study or studies upon which the presumption is based are not scientifically valid or (2)
proof that actual exposure to the compound will not cause the effects described. This phase
of the process can be characterized as focusing on the gathering of additional information
in the form of:

             —rebuttal comments.
             —additional information on risk.
             —input from other agencies:  primarily the United States Department of
               Agriculture for information on benefits and exposure, and the United States
               Department of Interior, Office of Endangered Species for information on the
               implications of an environmental trigger.

In the event that all the triggers have been successfully rebutted, the pesticide is re-
turned to the registration process and the RPAR is terminated for all or some of the uses.  The
results of this phase of the analysis is incorporated into a second position document (PD 2)
which states the Agency's regulatory action for the pesticide.  Any new information surfaced
during the rebuttal period is, of course, incorporated.  If the rebuttal is successful for all
or some of the uses, a PD 2 is published and becomes the final document of the RPAR process.

The Agency only produces and publishes a separate PD 2 in those cases where the rebuttal
has been successful.  When the rebuttal is not successful, the rebuttal assessment, the
risk analysis, the benefits analysis, risk/benefit synthesis and the proposed regulatory
position are presented in a document termed PD 2/3.

A PD 2/3 is composed of the

    —introductory chapter which reviews the RPAR criteria which gave rise to the
      RPAR on the pesticide in question,
    —the risk analysis which reviews rebuttal comments, estimates exposure and calculates
      risks for the registered uses of the pesticide,
    —the benefit analysis which represents the impact of total cancellation of the
      pesticide in question,
    —the risk/benefit analysis of each of the regulatory options under considera-
      tion for resolution of the RPAR, and
    —the recommended regulatory position.

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The full range of regulatory options which are available under the law are examined.  These
range from full registration to full cancellation.  Between the two ends of the regulatory
spectrum are the options that deal with labeling changes, classification, and use restric-
tions.  The impact of each of these options on the benefits and risk of each use of the
pesticide are considered.  The recommended decision is that which presents the best balance
of risks and benefits in the interest of public health and the environment.

At the conclusion of the risk/benefit evaluation, the completed PD 2/3 receives Agency review.
Discussions may be held; with registrants and other interested parties.  If the Assistant
Administrator for the Office of Pesticides and Toxic Substances approves this document, a
notice of preliminary determination and an announcement of the document's availability are
published in the Federal Register.

The FIFRA requires that the proposed decision (PD 2/3) be submitted to a Scientific
Advisory Panel for review of its scientific basis and to the Secretary of Agriculture for
comment. These comments, plus any industry or public comments on the proposed decision, are
evaluated.  The Agency's assessment of these comments, including the final decision on the
regulatory action, are announced in the Federal Reg ister.  These are contained in publi-
cation PD 4 which is also announced in the Federal Register.

     Activities After Completion of RPAR's—This document describes the status of those
chemicals that have, through a variety of means, concluded their RPAR analyses.  This includes
chemicals which have been returned to the registration process, those which have been cancelled
or on which restrictions have been imposed, and those which are currently in administrative
hearings, being reviewed in court, etc.


                                REGISTRATION STANDARDS

The Registration Standards program is EPA's approach to the reassessment and reregistra-
tion of pesticide products as mandated by Congress in FIFRA Section 3 (g).  The reassessment
involves a thorough review of the scientific data base underlying pesticide registrations and
an identification of essential but missing scientific studies which may not have been required
when the product was initially registered.  It may also require new testing or retesting to
ensure the safety of the compound by contemporary scientific standards.
                                                 IV

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The standards process involves making broad regulatory decisions at one time for a group
of pesticide products containing the same active ingredient rather than on a product-by-
product basis.  An estimated 600 standards will be developed representing most of the
35,000 currently registered pesticide products.  This approach to reregisration is
intended to simplify and streamline the regulatory process for both the Agency and pesti-
cide registrants and to assure the public that all registrations are supported by a
complete and valid scientific data base.

To establish the sequence of processing the approximate 600 active ingredients through the
Registration Standard review, active ingredients that have similar use(s) have been
clustered into 48 groups.  The groups are being processed in a sequence resulting from
their ranking in an equation based on production, human exposure, and ecological exposure
factors.  The ranking scheme was developed based on consideration of market competition,
availability of in-depth data on alternatives should the need for a Special Review arise,
and efficient use of EPA resources.

Each standard explains EPA's regulatory position on the use of the active ingredient in
all pesticide products containing that same chemical.  The standard contains an analysis
of the data on which the regulatory position is based, describes the rationale for the
regulatory position, and states the conditions that must be met to obtain pesticide
product registration.

The relationship of the Registration Standards process with the Special Review process
is that if the analysis of the data shows that a Special Review criterion has been met,
then the standard is issued announcing that a Special Review will be initiated for some or
all of the uses of the chemical.  When the Special Review process is completed, the result
of the Special Review will then be incorporated into the standard.

Registration Standards are developed in three phases:  1) Data Gathering, 2) Data
Evaluation, and 3) Regulatory Position Development followed by the issuance of the
Registration Standard Guidance Package.  For convenience, phases 2 and 3 are combined
in this report and the issued documents are identified separately in the attached listing.

1)  Data Gathering; The bibliography is sent to the major registrants for comment.  The
bibliography consists of all data in Agency files pertaining to the chemical, except that
in most cases efficacy data are not listed.  The bibliography will also include any
government studies (such as NCI studies) which have been conducted on the chemical and
other relevant material identified by Agency scientists.

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Registrants are asked to comment on the completeness of the entire list and whether
there are duplicates listed.  Registrants are asked to submit additional studies which
may never have been submitted to the Agency previously but which they consider to be
relevant to the review.

Once the bibliography has been commented on by the registrants, reviewed by Agency scien-
tists, and Agency scientists have identified which studies should be reviewed, hard copy
of all requested studies are retrieved from Agency files and provided to Agency scientists
for review.  The data gathering phase lasts about five months.

Once the data gathering phase is completed, and the use information is developed (usually
jointly by registrants and Agency use experts), the data evaluation phase is ready to
begin.

2) Data Evaluation; At the outset of the Data Evaluation phase, the Project Support Team,
which consists of all Agency staff involved in the Registration Standard review (Regis-
tration/reregistration Product Manager, use experts, data retrieval experts, and Agency
scientists) meet to exchange information regarding the chemical from a regulatory and
scientific perspective.  Following this meeting, registrants are invited to attend a
subsequent meeting to provide an overview from their perspective.  These two meetings are
designed to provide a context in which the scientists conduct their review.  Knowledge of
the regulatory history, the growth patterns of the chemical's use, general understanding
of the completeness of the data base, and discussion of any past regulatory/health
problems will help focus the review and increase the scientists' effectiveness.

With this perspective, scientists review data in each of five disciplines: product
chemistry, environmental fate, residue chemistry, toxicology, and ecological effects.
Efficacy data are reviewed only for products which control infectious microorganisms and
the growth of aflatoxins.  The scientists document their review of each study which they
consider relevant, and prepare a summary of what is known about the chemical in their
respective discipline.  Scientists also identify gaps in the data base which should be
filled to enable a complete scientific assessment to be made.  While the 40 CPR Part 158
guidelines* (currently proposed) are used as guidance to make the determination of data
gaps, each chemical is reviewed individually to determine, given its particular use
patterns and what is already known about it, what additional data are needed.  If the
resulting data needs differ from those in the Guidelines, the scientist provides written
justification for the deviation.  Depending on the size of the data base involved in the
review, this phase usually lasts from six to ten months.
*See p.viii for specific citation.
                                            VI

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3) Development of Regulatory Position and Issuance of Guidance Package; Once the Science
review is completed and scientists have recommended which additional data they believe are
necessary to complete the review, the project Support Team reconvenes to identify the
appropriate regulatory position for the chemical (that is, what percent active ingredient,
formulations, uses, etc. are registerable under the Standard and whether regulatory
restrictions such as label warnings or use by certified applicators only are required).
They also develop the rationale for the regulatory position and determine the data
requirements which need to be imposed to complete the review.  Included in this phase is
the tolerance reassessment which may result in the initiation of rulemaking to increase or
decrease tolerance levels.

Once the proposed regulatory position/rationale and data requirements are drafted, they
are provided to the registrant for comment.  The registrants may choose to modify his
manufacturing process or use patterns to eliminate the need for additional label warnings,
may provide further information which affects the exposure profile, or provide many other
observations or information which could affect the final statement.  Once the registrant
comments are received, the proposed regulatory position and rationale, data requirements,
scientific summaries, and bibliography are circulated to Agency management for review.

After the document is approved, study reviews and science summaries are placed in Agency
records for retrieval during subsequent reviews of the chemical (e.g.  registration amendments)
as their availability is expected to expedite the processing of future reviews.  Copies of
the study reviews and the science summaries are available through OPP's Freedom of Information
Section.  The regulatory position/ rationale, data requirements, and bibliography are
sent to the registrant in a document known as a Guidance Package which cites the authority
of Section 3{c)(2)(B) and Section 3 (g) of FIFRA.  Reregistration occurs when the registrant
agrees to comply with the data requirements, submits an updated Confidential Statement of
Formula if needed, agrees to comply with any regulatory restrictions placed on the chemical,
agrees to compensate other registrants for data considered relevant to the Standard, and
provides labelling reflecting completion of any product chemistry and acute toxicity data
requirements.
                                               VII

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 Issuance
«yintrants ana made available
 to the puBlic through the National Technical Information Service, 5285 Port Royal Road,
 Springfield,  VA 22152 telephone 703-487-4650.  Microfilm copies are available for $4.50;
 the price of  paper copies varies according to the length of the document.  Please furnish
 NTIS with the accession number or the PB number when ordering.
                              THE DATA CALL IN PROGRAM

 The Data Call In Program requires existing registrants of active pesticide chemicals to
 provide the Agency with needed long-term chronic toxicological studies under Section
 (c)(2)(B) of FIFRA.  Such studies are an integral part of the data base used to reassess
 each chemical during the reregistration process.  This reassessment is the forerunner of
 the development of the Registration Standard/Guidance Package, described previously.

 The purpose of Data Call In is to assure that data from needed long-term testing {2-4
 years)  are available or well underway before the pesticide chemical is reassessed for
 reregistration under Section 3(g).  These long-term chronic studies provide essential
 chronic health effects data needed to determine that a pesticide performs its intended
 function without causing unreasonable adverse effects on the environment (Section 3(c)(5))
 The program is being accelerated so that studies will be requested at least 2 to 4 years
 before  the data base is reassessed for reregistration.

 The four types of long-term toxicological data which are requested consist of C_hronic
 Feeding, Oncogenicity, Reproduction and Teratogenicity (informally referred to as the
 CORT studies).  These studies are described in the Toxicology Data Requirements part
 of the  "Pesticide Registration:  Proposed Data Requirements" regulation.*

 Under the Data Call In Program,  the Agency 1) determines which of the four types of
 chronic test data are required for each chemical, based on its use patterns and other
 factors; 2) identifies those test categories with no valid data submitted; and 3)
 ensures that studies are initiated by registrants of the pesticide product to fill
 those data gaps.  Registrant assistance is requested for the confirmation of data gaps.

 The sequence of processing the approximate 600 active ingredients through the Data Call
 In process is based on the priority cluster ranking in which active ingredients that
 have a  similar use(s) are clustered into about 50 groups and the groups are processed
 in sequence.  A notice of the availability of the final cluster ranking was published
*The Pesticide Registration Guidelines were
 reproposed as Part 158,40 CFR on November 24,
 1982 in 47 Federal Register 53192.
                                                Vlll

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in the Federal jtegister, 47 FR 3770, January 24, 1982.  Chemicals now being processed into
Registration Standards or which are in the RPAR process are deferred from the Data
Call In program.

In each Notice, the registrant can request the Agency to waive any or all of the specified
data requirements.  Registrants may request changes or waivers of the data requirements
because:

    1.  They believe the data requirements are inappropriate for their chemical.
    2.  They determine that their chemical involves only minor exposure and production.
        In addition, registrants may cite economic factors as precluding its capacity to
        incur the costs of testing.
    3.  They need a longer time period to complete the testing.
    4.  They wish to remove all registered uses which involve food crops/products and/or
        significant repeated exposure to humans and the environment.
    5.  They wish to use a protocol that differs from EPA or OECD guidelines.

If the Agency does not grant the change(s) or waiver(s), the registrants must arrange to
comply with the Notice.

If a registrant does not respond or comply with the Data Call In Notice, the Agency will
issue an Administrative Notice (NOIS—Notice Of I^ntent to jJuspend) compelling the regis-
trant to stop distributing the particular pesticide product(s) until compliance with the
Notice occurs.  The actual effect of a NOISe is to put a registration "on hold" until such
time as the registrant wishes to make his registration active.  Any such NOISe issued under
Section 3{c)(2){B) is rescinded when the Agency is informed and agrees that compliance
occurs.  Such Noises never, independently, result in cancellations and are therefore clear-
ly different from the FIFRA Section 6 suspensions which can later become cancellations
and cause the withdrawal of pesticide products from the market.

This report gives the status of all chemicals and clusters being processed through Data
Call In.  The status includes whether a Notice or equivalent has been issued and whether
the Agency has reached a final decision on all the waivers, exemptions, cancellations,
commitments and offers received from registrants.
                                          IX

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                                         RPARS ISSUED
                                                  September 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
CADMIUM
(Special Review Br.)
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Fetotoxlcity
o PD 1 published, 42 FR 56574
  (10/26/77); comment period
  closed 2/10/78.
o Risk/benefit assessment may be
  conducted in FY-84.
CAPTAN
(Special Review Br.)
CARBON TETRACHLORIDE
(Special Review Br.)
COAL TAR
(Special Review Br.)
o  Oncogenicity
o  Mutagenicity
o  Other Chronic Effects
o  Oncogenicity
o  Toxic effects on
   liver and kidney
o  Oncogenicity
o  Mutagenicity
o  PD 1 published, 45 FR 54938
   (8/18/80); comment period closed
   12/1/80: NTIS# PB81 109449.
o  Risk/benefit assessment is ongoing.

o  PD 1 published, 45 FR 68534
   (10/15/80); comment period
   closed 11/24/80: NTIS# PB80 121782.
o  Risk/benefit assessment is ongoing.
o  PD 1 published, 43 FR 48154
   (10/18/78); comment period closed
   9/30/78: NTIS# PB80 213879
o  PD 2/3 (wood uses only) completed
   and Notice of Determination pub-
   lished in 46 FR 13020 (2/19/81);
   comment period closed 5/20/81;Report
   # 540/9-82-004; NTIS # PB 82-229956
o  At 4/14/83 public meeting, proposed
   conclusion presented.  Comment period
   closed 5/13/83.
o  Final decision is being developed.

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                                  RPAR's ISSUED - Cont'd
                                                          September 1983
CHEMICAL (Class of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
    CURRENT
    STATUS
CREOSOTE
(Special Review Br.)
EPN
Ethyl p-nitro-
phenyl thionoben-
zenephosphonate
(PM-12)
ETHYLENE OXIDE
EtO
(Special Review Br.)
    o Oncogenicity
    o Mutagenicity
    o Neurotoxicity
    o Oncogenicity
    o Mutagenicity
    o Testicular Effects
o Same as above (Coal Tar/Creosote
  Coal Tar Neutral Oil PD 1 and
  PD 2/3 combined).  NTIS#82-229956
o PD 2/3 (wood uses only) completed
  and Notice of Determination pub-
  lished in 46 FR 13020 (2/19/81);
  comment period closed 5/20/81. Report
  # 540/9-82-004 NTIS # PB 82-229956
o At 4/14/83 public meeting proposed
  conclusion presented.  Comment period
  closed 5/13/83.
o Final decision is being developed.

o PD 1 published, 44 FR 54384
  (9/19/79); comment period closed
  12/29/79:  NTIS# PB80 216815
o Final Notice of Determination and
  Decision Document forwarded to
  Acting AA on June 30,1983.

o PD 1 published, 43 FR 3801
  (1/27/78); comment period closed
  5/15/78:  NTIS# PB80 213903
o Label improvement hospital use.
o Regulatory position document for
  hospital use being development.

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                                      RPARS ISSUED - Cont'd
                                                      September 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
INORGANIC             ,0
ARSENICALS             o
  Arsenic Acid,        o
  Arsenic Pentoxide,
  Arsenic Trioxide,
  Sodium Arsenate,
  Ammonium Arsenite,
  Sodium,
  Pyroarsenate,
  Lead Arsenate
  Basic and Standard)
  Calcium Arsenate,
  Sodium Arsenite,
  Copper Acetoarsenite
  (Special Review Br.)

PENTACHLOROPHENOL      o
AND DERIVATIVES        o
(Special Review Br.)   o
   Oncogenicity
   Mutagenicity
   Teratogenicity
   Oncogenicity
   Fetotoxicity
   Teratogenicity
                               o
   PD 1 published, 43 FR 42867
   (10/18/78); comment period closed
   2/12/79.
   PD 2/3 (wood uses only) completed
   and Notice of Determination pub-
   lished in 46 FR 13020 (2/19/81);
   comment period closed 5/20/81;
   At 4/14/83 public meeting proposed
   conclusion presented. Comment
   period closed 5/15/83.
   Final decision being developed.
   PD 1 published, 43 FR 48443
   (10/18/78); comment period closed
   2/12/79:  NTISt PB81 109464.
   PD 2/3 (wood used only) completed
   and Notice of Determination pub-
   lished in 46 FR 13020 (2/19/81);
   comment period closed 5/20/81;
   At 4/14/83 public meeting proposed
   conclusion presented. Comment
   period closed 5/13/83.
   Final decision being developed.

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                                     RPAR'S ISSUED - Cont'd
                                                     September 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11  CRITERIA
POSSIBLY MET OR EXCEEDED
STATUS
SODIUM FLUORO-
ACETATE/1080
(Special Review Br.)
o  Reduction in Non-target
   and Endangered Species
b  No antidote
2,4-5-TRICHLORO-
PHENOL
(Special Review Br.)
o  Oncogenicity
o  Fetotoxicity
   PD 1 published, 41 FR 52792
   (12/1/76); comment period closed
   3/15/77:  NTIS# PB80 216823
   PD 2/3 signed on 11/11/82.
   Release delayed to coincide
   with that of document addressing
   predator issues in early 1983.
   PD 2/3 resigned by Acting AA on
   6/29/83.

   PD 1 published, 42 FR 41268
   (9/15/78); comment period closed
   11/17/78.
   Possibility of TCDD contamination
   under investigation.
   3(c)(2)(B) letters issued requesting
   additional data from registrants.
   Some voluntary cancellations and
   reformulations being processed.
   Further review pending completion of
   2,4,5-T hearings.

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                                   PRE-RPAR REVIEW
                                          September 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
RONNEL
  0,0-dimethyl
  0-(2,4,5-trichlo-
  rophenyl) phosphoro-
  thioate (related to
  2,4,5-T)
  (Special Review Br.)
o  Oncogenicity
o  Teratogenicity
o  Fetotoxicity
   No action pending 2,4,5-T
   hearing settlement.

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                                  FINAL ACTIONS
                    VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS
                                        September 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ACRYLONITRILE
  (three products)
ARSENIC TRIOXIDE
o  Oncogenicity
o  Teratogenicity
o  Neurotoxicity

o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
BENZENE     -               o  Oncogenicity
  (all except one product) o  Mutagenicity and
                              Blood Disorders
BHC
CHLORANIL

CHLORDECONE
  Kepone
  (Products of six
  formulators)

COPPER ACETOARSENITE
o  Oncogenicity


o  Oncogenicity

o  Oncogenicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  43 FR 26310 (6/19/78).
o  42 FR 45944 (9/13/77).
                           o  Voluntary cancellations
                              completed.
o  43 FR 31432 (7/21/78)
   NTIS# PB80 216781

o  42 FR 3702 (1/19/77).

o  42 FR 38205 (7/27/77)
   NTIS# PB80 216773
o  42 FR 18422 (4/7/77).
COPPER ARSENATE (Basic)
  (all products)

ERBON
o  Oncogenicity
o  Oncogenicity
o  Teratogenicity
o  Fetotoxicity
o  42 FR 18422 (4/7/77).
o  45 FR 58770 (10/4/80)

-------
                                   FINAL ACTIONS
                 VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS - CONT'D
                                          September 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ISOCYANURATES
  (some products)
MONORON
  (some products)

NITROFEN (TOK)
OMPA
  Octamethylpyro-
  phosphoramide

PERTHANE
  (many products)

PHENARSAZINE CHLORIDE

SAFROLE
SODIUM ARSENITE
   (two products)
STROBANE

TRYSBEN
o  Kidney effects
o  Oncogenicity
o  Teratogenicity
o  Mutagenicity
o  Oncogenicity

o  Oncogenicity
o  Oncogenicity
o  None

o  Oncogenicity
o  Mutagenicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity

o  Oncogenicity

o  Oncogenicity
o  Voluntary cancellations
   being processed.
o  Registrants have either
   undertaken or scheduled
   numerous toxicological
   studies.

o  42 FR 41320 (8/16/77).
o  Targeted for 11/83.
o  41 FR 21859 (5/28/76).
o  45 FR 41694 (6/20/80).


o  42 FR 59776 (11/21/77)

o  42 FR 11039 (2/25/77).
o  42 FR 16844 (3/30/77).
o  42 FR 29957 (6/10/77).

o  43 FR 48267 (10/18/78)
o  41 FR 26607 (6/28/76).

o  43 FR 5782 (2/9/78).

-------
                         NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED    September 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ALDRIN/DIELDRIN
CHLORDANE/HEPTACHLOR
CHLORDECONE
  Kepone
DBCP
ODD (TDE)
DDT
DINITRAMINE
ENDRIN
o  Oncogenicity
o  Reductions in Non-target
   and endangered species

o  Oncogenicity
o  Oncogenicity
o  Mutagenicity
o  Reproductive Effects
o  Oncogenicity
o  Oncogenicity
o  Teratogenicity
o  Reduction in En-
   dangered Species
   and Non-target
   Species
o  39 FR 37216 (10/18/74);
   (Cancellation of most uses)

o  Notice of Intent to Cancel
   39 FR 41298 (11/26/74).
   (Cancellation of most uses)

o  PD 1 published, 41 FR 12333
   (3/25/76).
o  PD 4 published, 42 FR 18885
   (4/11/77).
o  Notice of Intent to Cancel
   42 FR 18885 (4/11/77).

o  See listing under "RPAR's
   COMPLETED".
   36 FR 5254 (3/18/71);
   (Cancelled).

   37 FR 13369 (7/7/72);
   (Cancellation of most uses),

   Notice of Intent to Suspend
   under Sec. 3(c)(2)(B)
   issued on 9/28/82.

   See listing under "RPAR's
   COMPLETED".
                                           8,

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                      NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED Cont'd   September 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
MI REX
2,4,5-T/SILVEX
o  Oncogenicity
o  Teratogenicity
o  Fetotoxicity
o  41 FR 56703 (12/29/76);
   (Most uses cancelled).

o  PD 1 published, 43 FR 17116
   (4/21/78):  2,4,5-T - NTIS#
   PB80 212665
o  Emergency Suspension Order and
   Notice of Intent to Cancel pub-
   lished, 44 FR 15874 (3/15/79):
   2,4,5-T -  NTIS# PB80 225923
   Silvex -  NTIS# PB80 226376
o  PD 4 published, 44 FR 72316
   (12/13/79).
o  Cancellation Hearings began
   3/14/80. The Agency is nego.
   w/ involved parties to resolve
   the hearing.

-------
                             NOTICE OF INTENT TO REGISTER ISSUED
                            (Returned to the Registration Process)
                                                      September 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
CACODYLIC ACID
AND SALTS
  (PM-23)
CARBARYL
 (PM-12)
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
   Insufficient evidence to issue a
   RPAR.
   Decision document published in
   Federal Register, 47 FR 20376,
   (5/12/82).  Returned to the
   Registration process in Dec. 1981
   with the stipulation that pursuant
   to FIFRA Section 3(c)(2)(B), data
   on the rate of dermal absorption be
   submitted, knapsack/hand sprayer
   applicators treating ditch banks
   and rights-of-way will wear
   respirators or masks, and labels
   recommend masks for homeusers
   employing knapsacks or hand
   sprayers.

   45 FR 81869 (12/12/80). The Agency
   has returned this compound to the
   registration process with the stipu-
   lation that the following measures
   b'e considered:  1) a FIFRA Section
   3(c)(2)(B) action that registrants
   remedy data limitations identified
   in pre-RPAR review and, 2) appro-
   priate label changes be made to
   minimize exposure to carbaryl.
   Both measures are being considered
   in the Reregistration review of
   this chemical.
                                         10

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                               NOTICE OF INTENT TO REGISTER ISSUED
                              (Returned to the Registration Process)
                                                      September 1983
CHEMICAL
(Class of Chemicals)
40 CPR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
 DATE OF FEDERAL
REGISTER PUBLICATION
CHLOROFORM
  Trichloro-
  methane
  (PM-16)
DICHLORVOS
  DDVP
  2,2-dichlorovinyl
  dimethyl phosphate
  (PM-15)
DIFLUBENZURON
  Dimilin
   (PM-17)
o  Oncogenicity
o  Oncogenicity
   Mutagenicity
o  Reproductive Effects
o  Fetotoxicity
o  Neurotoxicity
o  Oncogenicity
o  Hazard to Wildlife and
   other Chronic Effects
   PD 1 published, 41 FR 14588
   (4/6/76); comment period closed
   7/23/76.
   FR Notice announcing termination
   of this RPAR issued in December,
   1982. The agency determined that
   applicator exposure had been
   reduced to a minimum as a result
   of label amendments. Also regis-
   trants were required to submit
   data to establish tolerances of
   permissible residues on raw
   agricultural commodities.

   47 FR 45075 (10/13/82).
   NTIS no. not available.
   Returned to the Registration
   Process September 29, 1982
   stating that the Agency will
   reassess carcinogenic potential
   ^nd the need for additional
   Oncogenicity data upon comple-
   tion of an in progress NCI bio-
   assay.  Additional tests on
   mutagenicity were required.

   RPAR action completed in April 1979
   Registrant consented to restricted
   uses.
                                             11

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                                NOTICE OF INTENT TO REGISTER ISSUED
                               (Returned to the Registration Process)
                                                       September 1983
CHEMICAL
(Class of Chemicals)
  40 CFR 162.11 CRITERIA
  POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
MALEIC HYDRAZIDE
  MH
 (PM-25)
  o  Oncogenicity
  o  Mutagenicity
  o  Reproductive Effects
METHANEARSONATES
  includes Amine
  Methanearsonate,
  Calcium Acid Meth-
  anearsonate, Mono-
  ammonium Methane-
  arsonate (MAMA),
  Monosodium Methane-
  arsonate (MSMA),
  Disodium Methane-
  arsonate (DSMA)
  (Special Review Br.)

NALED
  (PM-16)
o  Oncogenicity
o  Mutagenicity
o  Mutagenicity
o  Fetotoxicity
o  Reproductive Effects
o  PD 1 published, 42 FR 56920
   (10/28/77), comment period closed
   12/14/77:  NTIS# PB80 216740
o  Decision document returning maleic
   hydrazide and salts (K-MH, DEA-MH)
   to registration process signed 6/28/82.
   Report #540/9-82-010? NTIS# PB 82240300
   FR Notice has been combined with
   chloroform (see chloroform entry).
o  Additional reproductive and muta-
   genicity studies have been per-
   formed on K-MH as required.
o  Registrants decided not to per-
   form similar tests on DEA-MH and
   thus DEA-MH was suspended 11/81.

o  On 6/28/83 the pre-RPAR review for
   methanearsonate chemicals was
   completed and a decision memo was
   approved returning these chemicals
   to the normal registration process.
   The existing evidence was inadequate
   tio initiate an RPAR for the chemicals.
   however,additional data will be
   required through a 3(c)(2)(B) notice
   to determine if there are any risk
   concerns.
   Chemical returned to normal registra-
   tion process on 6/30/83. Based on a re-
   view of all available data, no valid
   tests or definitive evidence exist which
   meet or exceed the RPAR risk criteria.
   However, additional tests have been re-
   quired and will be reviewed to determine
   whether there are any risks of concern.
                                                  12

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                                NOTICE OF INTENT TO REGISTER ISSUED
                               (Returned to theRegistration Process)
                                                       September 1983
CHEMICAL
(Class o£ Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
10 ,10'Oxybisphen-
  oxarsine
  {Some uses)
   (PM-22)
PARAQUAT
 (PM-25)
PIPERONYL BUTOXIDE
  (PM-17)
ROTENONE
 (PM-17)
o  (Arsenical Compound)
   suspected:
   - Oncogenicity
   - Mutagenicity
   - Teratogenicity

o  Emergency Treatment
o  Chronic Effects
o  Co-Carcinogenicity
o  Carcinogenicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Reproductive Effects
o  Chronic Toxicity
o  Significant Wildlife
   Populations Reductions
o  Acute Toxicity to
   Aquatic Wildlife
o
o
   Returned to the Registration
   Process on April 9, 1979 based
   on Memo indicating no evidence
   of Oncogenicity.
Decision document returning
paraquat to the Registration
Process was signed on 6/29/82.
FR Notice 47 FR 45075, pub-
lished October 13, 1982. NTIS
no. not available.  Decision
Document outlines data gaps and
voluntary cancellation of certain
noncrop use sites.

Decision document complete.
FR Notice 47 FR 20376 pub-
lished 5/12/82.  NTIS #PB 83-137901
Returned to the Registration
Process on May 12, 1982.
Section 3(c)(2)(B) notice
requesting additional data
issued on Sept. 30, 1982.

Notice of Availability of De-
cision document published,
46 FR 36745 (July 15, 1981). NTIS
no. not available. Returned to
Registration Process based on
finding no unreasonable adverse
effects.
                                               13

-------
                               NOTICE OF INTENT TO REGISTER ISSUED
                              (Returned to theRegistration Process)
                                                     September 1983
CHEMICAL
(Class of Chemicals)
 40 CFR 162.11 CRITERIA
 POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
1081
(PM-16)
TERBUTRYN
(PM-25)
TRIALLATE
(PM-25)
S,S,S-TRIBUTYL
PHOSPHOROTRITHIOATE
(DBF)
(PM-25)
   Acute Toxicity to Mam-
   malian and Avian Species
   Reduction in endangered
   and non target species
   Acute Toxicity without
   antidote.
o  Oncogenicity
o  Mutagenicity
o  Reproductive Effects
o  Oncogenicity
o  Mutagenicity
o  Neurotoxicity
o  PD 1 published, 41 FR 52792
   (12/1/76):  NTIS# PB80 216823
o  PD 2 published  45 FR 13189.
   (2/28/80): NTIS# PB80 216831.
o  Returned to Registration Pro-
   cess with the restriction
   that it be used only in sewers.

o  PRE-RPAR evaluation completed.
o  Returned to the Registration
   Process. Registrants agreed
   to change label to reduce
   applicator risk to acceptable
   levels. 47 FR 20376, published
   5/12/82. NTIS no. not available.

o  45 FR 82349 (12/15/80). The
   Agency determined that, in light
   of the low level of exposure, it
   should be returned to the regis-
   tration process stipulating that
   4 FIFRA 3(c)(2)(B) action be
   initiated to obtain necessary
   toxicity data to evaluate its
   hazards.

o  PRE-RPAR evaluation completed.
o  Returned to Registration Divison,
   11/30/81, based on finding of no
   potential unreasonable adverse
   effects. Registrants agreed to
   practice clothing requirement.
   47 FR 20376, published 5/12/82.
   NTIS no. not available.
                                             14

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                             NOTICE OF INTENT TO REGISTER ISSUED
                            (Returned to^ the Registration Process)
                                                  September 1983
CHEMICAL
(Class of Chemicals)
40C CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE 0
REGISTER PUBLICATION
TRIBUTYL PHOSPHORO-
TRITHIOITB
(Merphos)
(PM-25)
o  Neurotoxicity
TRICHLORFON
(PM-16)
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Fetotoxicity
o  Reproductive Effects
o  PRE-RPAR evaluation completed.
o  Returned to Registration Divi-
   sion, 11/30/81, based on finding
   no potential unreasonable adverse
   effects. Registrants agreed to
   protective clothing requirement.
   47 FR 20376 published 5/12/82.
   NTIS no. not available.

o  Removed from Pre-RPAR review as
   it chemically relates to dichlorvos.
   See dichlorvos.
                                            15

-------
                                      RPARS COMPLETED
                                                     September 1983
CHEMICAL (Class of
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA        CURRENT
POSSIBLY MET OR EXCEEDED      STATUS
AMITRAZ
  Baam
(PM-12)
o  Oncogenicity
BENOMYL
o  Reduction in non-target
o  Mutagenicity
o  Teratogenicity
o  Reproductive Effects
o  Hazard to Wildlife
o
o
PD 1 published, 42 FR 18299
(4/6/77); comment period closed
7/18/77: NTIS# PB80 212046
PD 2/3 completed and Notice of
Determination published, 44 FR
2678 (1/12/79); comment period
closed 2/12/79: NTIS# PB80 211436
PD 4 published, 44 FR 32736
(6/7/79); 44 FR 59938 (10/7/79)
(correction):  NTIS# PB80 211428
- conditional registration approved
  for pears but not for apples.
- registrants will conduct an onco-
  genicity study and collect
  additional benefits data.
- tolerance for pears approved 12/6/79.

PD 1 published, 42 FR 61788 (12/6/77).
PD 2/3 completed and Notice of
Determination published, 44 FR
51166 (8/30/79); comment period
closed 9/28/79.
PD 4 completed and Notice of
Determination published, 47 FR 46747
(10/20/82).  NTIS# PB 83-148189.
The Notice requires use of either cloth
or commercially available disposable
dust masks by mixer/loaders of benomyl
intended for aerial application and
that registrants of benomyl products
conduct field monitoring studies to
identify residues that may enter
aquatic sites after use on rice.

-------
                                RPARs COMPLETED - Cont'd
                                                       September 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA        CURRENT
POSSIBLY MET OR EXCEEDED      STATUS
CHLOROBENZILATE
(PM-12)
o
o
Oncogenicity
Testicular Effects
DBCP
  1, 2-dibromo-
  3-chloropropane
  (PM-21)
o
o
Oncogenicity
Reproductive Effects
PD 1 published, 41 FR 21517
(5/26/76); comment period closed
7/28/76.
PD 2/3  and Notice of Proposed Deter-
mination published, 43 FR 29824
(7/11/78); comment period closed
8/10/78:  NTIS# PB80 213887
Final Determination based on PD 2/3
published, 43 FR 29824 (7/11/78).
PD 4 and Notice of Intent to Cancel
published, 44 FR 9547 (2/13/79):
NTIS# PB80 213929

PD 1 published, 42 FR 48026
(9/22/77); comment period closed
11/7/77.
Suspension Order and Notice of Intent
to Cancel published, 42 FR 57543
(11/3/77).
Amended Notice of Intent to Cancel
and PD 2/3/4/ published, 43 FR 40911
(9/13/78):  NTIS # PB80 213853
Notice of Intent to Suspend all pro-
ducts issued, 44 FR 41783 (7/18/79).
Suspension Order (affecting all uses
except pineapple) and Notice of Intent
to Cancel all Uses published, 44 FR
65135 (10/29/79).
Agreement reached with registrants
that all uses, except on pineapples,
are cancelled.
                                             17

-------
                                      RPARs COMPLETED - Cont'd
                                                       September 1983
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
DIALLATE
  (PM-25)
DIMETHOATE
  (PM-16)
o  Oncogenicity
o  Mutagenicity
o  Oncogenicity
o  Mutagenicity
o  Fetotoxicity
o  Reproductive effects
                                                      o
   PD 1 published, 42 FR 27669
   (5/31/77); comment period closed
   9/9/77:  NTIS* PB80 212863
   PD 2/3 completed and Notice of
   Determination published, 45 FR
   38437 (6/9/80); comment period
   closed 7/9/80:  NTIS# PB80 216849:
   PD 4 completed and announced in
   Federal Register, 47 FR 27109
   (6/23/82). NTIS no. not available.
   Classifies current products for
   restricted use by certified
   applicators wearing protective
   clothing.

   PD 1 published, 42 FR 45806
   (9/22/77); comment period closed
   1/6/78.
   PD 2/3 completed and Notice of
   Determination published, 44 FR
   66558 (11/19/79); comment period
   closed 12/19/79:  NTISf PB80
   213846
   PD 4 published, 46 FR 5334
   (1/19/81). NTIS no. not available.
   Registration Standard approved and
   signed 3/31/83.
                                             18

-------
                                    RPARs COMPLETED - Cont'd
                                                     September 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
EBDC's
  Ethylenebis-
  dithiocarbam-
  ates, maneb,
  mancozeb,
  metirara, nabam,
  zineb, amobam
  (PM-21)
ENDRIN
 (PM-15)
o  Oncogenicity
6  Teratogenicity
o  Hazard to Wildlife
o  Oncogenicity
o  Teratogenicity
o  Reduction in en-
   dangered species and
   nontarget species
   PD 1 published,_42 FR 40618
   (8/10/77); comment period closed
   12/23/77.
   Decision Document and Final
   Determination published, 47 FR
   47669 (10/27/82). NTIS no. not
   available.  The Notice returned
   EBDC products to the Registration
   Process on condition that certain
   use precautions are added to the
   product labels and registrants
   agree to generate additional
   toxicology data.
   Data Call-in Notices requesting
   registrants to generate the
   needed data on 6 EBDC's and
   ETU have been issued.

   PD 1 published, 41 FR 31316
   (7/26/76); comment period closed
   11/4/76:  NTIS# PB81 112690.
   PD 2/3 completed and Notice of
   Proposed Determination published,
   43 FR 51132 (11/2/78).
   PD 4 published, (including can-
   cellations) 44 FR 43631 (7/25/79)
   NTIS# PB81 10980.
                                              19

-------
                                     RPARs COMPLETED - Cont'd
                                                  September 1983
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
ENDRIN cont'd
 (PM-15)
   Oncogenicity
   Teratogenicity
   Reduction in en-
   dangered species and
   nontarget species
ETHYLENE DIBROMIDE
  EDB
 (Spcial Review Br
    o Oncogenicity
    o Mutagenicity
    o Reproductive Effects
GOAL
  (PM-25)
o  Oncogenicity
   PD 4 follow-up notice mailed
   8/28/80, cancellations began
   30 days later.
     - Some uses are conditionally
       registered because require-
       ments have been met.
   Herb Harrison, Registration
   Division (557-2200) is contact
   point for inquiries.

   PD 1 published, 42 PR 63134
   (12/14/77); comment period closed
   4/3/78:  NTIS# PB80 109456.
   PD 2/3 completed and Notice of
   Determination published, 45 FR
   81586 (12/10/81);  comment period
   closed 3/9/81.
   PD 4 and FR Notice were approved on
   9/28/83.  FR publication on 9/30/83
   emergency suspensing soil fumigation
   uses and cancelling others.

   PD 1/2/3 completed. NTIS# PB82
   172289.
   PD 4 published in Federal
   Register on June 23, 1982;47 FR
   27118; NTIS# PB82 185133.
   The decision is to continue use
   of the herbicide subject to
   certain restrictions (on PCE)
   pertaining to formulation of
   the product.
                                               20 .

-------
                                    RPARs COMPLETED - Cont'd
                                                     September 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET DR EXCEEDED
CURRENT
STATUS
LINDANE
 (Special Review Br.)
PCNB
  Pentachloro-
  nitrobenzene
  (PM-21)
PRONAMIDE
 (PM-25)
 o  Oncogenicity
 o  Teratogenicity
 o  Reproductive Effects
 o  Acute Toxicity
 o  Other Chronic Effects
 o  Oncogenicity
   o  Oncogenicity
                                o
                                o
   PD 1 published, 42 FR 9816
   (2/18/77); comment period closed
   6/20/77:  NTIS# PB80 213911
   PD 2/3 completed and Notice of
   Determination published, 45 FR
   45362 (7/3/80); comment period
   closed 9/15/80.
   PD 4, FR Notice and decision
   package were approved on 9/30/83.
   The notice was published 10/19/83.
   The decision cancels the indoor use
   of smoke fumigation devices and the
   use of dog dips to treat pests,
   other than mites.  All other uses
   will be continued with use restric-
   tions and label modifications.

   PD 1 published, 42 FR 61894
   (10/13/77); comment period closed
   2/6/78:  NTIS# PB80 216799
   PD 2/3 in Agency review.
   RPAR terminated through negotiated
   agreement with registrants to
   reduce levels of the HCB
   contaminant and to make label
   changes to reduce exposure.
   47 FR 18177, published 4/19/82.

   PD 1 published, 42 FR 32302
   (5/20/77); comment period closed
   8/29/77:  NTIS# PB81 109472.
   PD 2/3 completed and Notice of
   Proposed Determination published,
   44 FR 3083 (1/15/79); comment period
   closed 2/14/79:  NTIS# PB80 213911.
                                          21

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                                     RPARs COMPLETED - Cont'd
                                                                    September 1983
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE
SPED BRANCH
             40 CFR 162.11 CRITERIA
             POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
PRONAMIDE
  (PM-25)
cont'd
STRYCHNINE/
STRYCHNINE
SULFATE
(Special Review Br.)
                Reduction in Non-target
                and Endangered Species
o  PD 4 completed and Final Determination
   published, 44 FR 61640 (10/26/79):
   NTIS# PB81 112716.  The following
   actions were taken: Cancellation of
   registrations of products allowing
   hand spray applications, except for
   use on ornamentals and nursery stock;
   cancellation of registrations of
   products unless the registrant modi-
   fies the terms and conditions to
   allow certain uses of wettable powder
   products only by or under direct
   supervision of certified applicators;
   modification of labeling of wettable
   powder products to include specific
   general precautions, directions as to
   protective clothing to be worn, dilu-
   tion instructions for wettable powder
   products, and watering instructions
   for granular products used on turf;
   Agency revision of the lettuce
   tolerance from 2 ppm to Ippm; and
   required residue data on lettuce.

o  PD 1 published, 42 FR 2713
   (1/13/77); comment period closed
   3/15/77:  NTIS# PB80 216807.
o  PD 2/3 completed and Notice of
   Determination published, 45 FR
   73602 (11/5/80); comment period
   closed 9/30/81:  NTIS# PB81 123960.
                                          22

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                                     RPARs COMPLETED - Cont'd
                                                                September 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
           40 CFR 162.11 CRITERIA
           POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
STRYCHNINE/ cont'd
STRYCHNINE
SULFATE
(Special Review Branch)
THIOPHANATE
  (PM-21)
METHYL     o  Mutagenicity
           o  Reduction in Non-
              target Species
              (Rebutted)
TOXAPHENE
  (PM-12)
           o  Oncogenicity
           o  Population reduction
              non-target animal species
           o  Acute toxicity to
              aquatic organisms
           o  Chronic effects to
              wildlife
                                                      o
                                                      o
   PD 4, PR Notice and decision package
   were approved on 9/30/83.  FR was
   published 10/19/83.  Decision
   cancels use of strychnine for
   control of prairie dogs and several
   other rodents and small mammals.
   All other uses will require label
   mod ificat ions<

   PD 1 published, 42 FR 61940
   12/7/77); comment period closed
   3/27/78:  NTIS #PB80 216856.
   PD 2 completed and Notice of
   Proposed Determination pub-
   lished, 44 FR 58798 (10/11/79).
   PD 4 completed and Notice of
   Determination published, 47 FR
   46747 (10/20/82).  NTIS no.
   not available.

   PD 1 published, 42 FR 26860
   (5/27/77); comment period closed
   9/13/77: NTIS# PB80 216732.
   Decision Document published 11/29/83
   Final Notice of Determination
   published in 47 FR 53784 (11/29/82).
   NTIS# PB 83- 144204.
                                              23

-------
                                     RPARs COMPLETED - Cont'd
                                                                  September 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
             40 CFR 162.11 CRITERIA
             POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
TOXAPHENE
  (PM-12)
cont'd
2,4,5-T/SILVEX
  (PM-22)
 or(PM-23)
            o  oncogenicity
            o  Teratogenicity
            o  Fetotoxicity
TRIFLURALIN
TrefIan
(PM-23)
           o  Oncogenicity
           o  Mutagenicity
   That notice presented the Agency
   decision to cancel registrations
   for most uses and continue regis-
   tration of certain uses under
   specific terms and conditions.
   The continued uses are:  corn,
   cotton and small grain for specific
   insect infestation (emergency use
   only),  pineapples and bananas for
   specific insects in Puerto Rico and
   the Virgin Islands only, and scabies
   treatments of cattle and sheep.

  PD 4 completed and Final Deter-
  mination published, 44 FR 72316
  (12/13/79); applies to uses not
  included in suspension actions
  described in prior section under
  "Notice of Intent to Cancel
  Suspend Issued".

  PD 1/2/3/ published, 44 FR 50911
  (8/30/79); comment period closed
  11/13/79:  NTIS# PB80 213937.
  PD 4 published August 4, 1982,
  47 FR 33777:  Report #540/9-82-011;
  NTIS# PB82 263252.
  Trifluralin registrations allowed
  to continue if the total N-nitro-
  samine contamination is kept below
  0.5 ppm for technical products and
  below a figure based on trifluralin
  content for formulated products.

-------
                  REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION  September 1983
CHEMICAL (Class
of Chemicals)
      RESPONSIBLE
      RD BRANCH/PM
TYPE OF
CHEMICAL
AMITRAZ

BTC 2125

CAPTAN

COPPER SULFATE & related hydrates

CYHEXATIN

3,5-Dibromosalicylanilide

DIFLUBENZURON

DIPROPETRYN

ENDRIN

EPN

GLYPHOSATE

HCL

HEXYLENE GLYCOL

HYAMINE 3500

METRIBUZIN

MONOCROTOPHOS
      I-R Branch/PM-12

Disinfectants Br./PM-31

      H-F Branch/PM-21

      H-F Branch/PM-21

      I-R Branch/PM-12

Disinfectants Br./PM-32

      I-R Branch/PM-17

      H-F Branch/PM-25

      I-R Branch/PM-15

      I-R Branch/PM-12

      H-F Branch/PM-25

Disinfectants Br./PM-32

Disinfectants Br./PM-31

Disinfectants Branch/PM-31

     H-F Branch/PM-25

     I-R Branch/PM-16
Insecticide

Disinfectant

Fungicide

Fungicide

Insecticide

Disinfectant

Insecticide

Herbicide

Insecticide

Insecticide

Herbicide

Disinfectant

Disinfectant

Disinfectant

Herbicide

Insecticide
                                           25

-------
                   REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION  September 1983
CHEMICAL (Class
of Chemicals)
      RESPONSIBLE
      RD BRANCH/PM
TYPE OF
CHEMICAL
NAPTALAM

NEOMYCIN SULFATE

NITRAPYRIN

OMADINE-SODIUM

ORYZALIN

PARATHION

POTASSIUM & SODIUM HYDROXIDE

POTASSIUM PERMANGANATE

SODIUM BISULFATE

SULFURYL FLUORIDE

TCC

THIOPHANATE Ethyl

THIOPHANATE Methyl
      H-F Branch/PM-25

      H-F Branch/PM-21

      H-F Branch/PM-23

Disinfectants Br./PM-32

      H-F Branch/PM-25

      I-R Branch/PM-12

Disinfectants Br./PM-32

Disinfectants Br./PM-32

Disinfectants Br./PM-32

      I-R Branch/PM-16

Disinfectants Br./PM-32

      H-F Branch/PM-21

      H-F Branch/PM-21
Herbicide

Disinfectant

Herbicide

Disinfectant

Herbicide

Insecticide

Disinfectant

Disinfectant

Disinfectant

Insecticide

Disinfectant

Fungicide

Fungicide
                                              26

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            REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND  September 1983
                         DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
o£ Chemicals)
RESPONSIBLE
RD BRANCH/PM
TYPE OF
CHEMICAL
ACEPHATE

ALACHLOR

ALDICARB

AMITROLE

ANILAZINE

ARSENICALS

BENOMYL

BENTAZON(Na)(Basagram)

CAPTAFOL

CARBARYL

CARBOFENOTHION

CARBOFURAN

CHLORDIMEFORM/HCL

CHLOROBENZILATE

CHLOROTHALONIL

CHLORPYRIFOS

CYANAZINE
I-R Branch/PM-16

H-F Branch/PM-25

I-R Bcanch/PM-12

SR Branch

H-F Branch/PM-21

H-F Branch/PM-21

H-F Branch/PM-21

H-F Branch/PM-25

H-F Branch/PM-21

I-R Branch/PM-12

I-R Branch/PM-16

I-R Branch/PM-12

I-R Branch/PM-12

I-R Branch/PM-12

H-F Branch/PM-21

I-R Branch/PM-12

H-F Branch/PM-25
Insecticide

Herbicide

Insecticide

Herbicide

Herbicide

Fungicide

Fungicide

Herbicide

Fungicide

Insecticide

Insecticide

Insecticide

Insecticide

Insecticide

Herbicide

Insecticide

Herbicide
                                           27

-------
             REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND  September  1983
                          DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
of Chemicals)
    RESPONSIBLE
    RD BRANCH/PM
TYPE OF
CHEMICAL
DAMINOZIDE(Alar)

DCNA

DEMETON

DICOFOL

DISULFOTON

FENSULFOTHION

FLUCHLORALIN (Basalin)

FONOFOS

HELIOTHIS

LINURON

NORFLURAZON

PENDIMETHALIN (Prowl)

PHORATE

PICLORAM

POTASSIUM Blfluoride

POTASSIUM BROMIDE

POTASSIUM IODATE
    H-F Branch/PM-25

    H-F Branch/PM-25

    I-R Branch/PM-16

    I-R Branch/PM-12

    I-R Branch/PM-15

    I-R Branch/PM-15

    H-F Branch/PM-25

    I-R Branch/PM-16

    I-R Branch/PM-17

    H-F Branch/PM-25

    H-F Branch/PM-23

    H-F Branch/PM-25

    I-R Branch/PM-16

    SR Branch

Disinfectants Br./PM-32

Disinfectants Br./PM-32

Disinfectants Br./PM-32
Herbicide

Herbicide

Insecticide

Insecticide

Insecticide

Insecticide

Herbicide

Insecticide

Insecticide

Herbicide

Herbicide

Herbicide

Insecticide

Herbicide

Disinfectant

Disinfectant

Disinfectant
                                                28

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              REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND    September 1983
                           DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
of Chemica1s)
  RESPONSIBLE
  RD BRANCH/PM
TYPE OF
CHEMICAL
PROPACHLOR

SIMAZINE

TEBUTHIURON

THIRAM

TPTH(Triphehyltin Hydroxide)

TRICHLORFON
H-F Branch/PM-25

H-F Branch/PM-23

H-F Branch/PM-25

H-F Branch/PM-21

H-F Branch/PM-21

I-R Branch/PM-16
Herbicide

Herbicide

Herbicide

Fungicide

Fungicide

Insecticide
                                             29

-------
                                 REGISTRATION STANDARDS - ISSUED
                                                September 1983
CHEMICAL & REPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
ALUMINUM PHOSPHIDE
  (PM 16)
ALIETTE
  (PM 22)

4-AMINOPYRIDINE (AVITROL)
  (PM 16)
AMMONIUM SULFAMATE
  (PM 25)
AS PON
  (PM 16)

ATRAZINE (PM 25)

BARIUM METABORATE
  (PM 22)

BIFENOX
  (PM 25)

BKLFI-2
  (PM 32)
 Insecticide
 Fungicide
 Bird Chemosteri- '
   lants. Toxicants
   and Repellents

 Herbicide
 Insecticide


 Herbicide

 Fungicide


 Herbicide


 Disinfectant
 October 1981
 NTIS# PB82 137514
 June 30, 1983*
 September 1980*
 11/24/81
 RS-81-017
 PB82-137514
 6/30/83
                                                                                   * *
 9/30/80**.
 June 1981           8/5/81
 NTIS# PB82 133570.  RS-81-012
                     PB82-133570.
 September 1980*     9/30/80
 NTIS# PB81 112484.
                                                                                   **
 September 30, 1983*

 April 14, 1983*     6/27/83**
 June 1981*


 December 1981*
 8/12/81
 RS-82-007**

 12/29/81
 RS-82-002/**
*  RS or NTIS PB number not available.
** Ntis numbers not available.
                                                30

-------
                              REGISTRATION STANDARDS - ISSUED Cont'd
                                                   September 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
BOLSTAR (SULPROFOS)
  (PM 12)
Insecticide
BORIC ACID (pending 25(b) exemption decision)
  (PM 16)
BROMACIL & SALTS
  (PM 25)

BUTYLATE (PM 25)

CARBOXIN (VITAVAX®)
  (PM 21)

CHLORAMBEN
  (PM 25)

CHLORONEB
  (PM 21)

CHLOROPICRIN
  (PM 21)

COUMAPHOS
  (PM 15)

CRYOLITE
  (PM 17)

CYCLOHEXIMIDE
  (PM 21)
Herbicide


Herbicide

Fungicide


Herbicide


Fungicide


Insecticide


Insecticide


Insecticide


Fungicide
August 1981
NTIS# PB82 133646
September 1982*
September 30, 1983*

August 1981
NTIS# PB82 132994

August 1981
NTIS# PB82 134347

September 1980
NTIS# PB81 123804.

September 1982*
August 1981
NTIS# PB82 133570.

June 23, 1983*
September 1982*
8/10/81
RS-81-008
PB-82-133646
9/30/82**.
8/12/81
RS-81-007

8/12/81
RS-81-015

9/30/80**.


9/28/82**.
9/4/81
RS-81-013
PB82-133357.
June 28, 1983**
9/24/82**.
*  RS or NTIS PB number not available.
** NTIS numbers not available.
                                                31

-------
                              REGISTRATION  STANDARDS  -  ISSUED Cont'd
                    September 1983

CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
DEBT
(PM 25)
DIALIFOR)
(PM 16)
DIALLATE
(PM 25)
DICAMBA
(PM 25)
DICHLONE
(PM 21)
DICROTOPHOS (BIDRIN®)
(PM 16)
DIMETHOATE
(PM 16)
DIOXATHION
(PM 15)
DIURON
(PM 25)
ENDOSULFAN
TYPE OF
CHEMICAL
Insecticide

Insecticide

Herbicide

Herbicide

Fungicide

Insecticide

Insecticide

Insecticide

Herbicide

Insecticide
DATE OF
STANDARD
& NTIS NOS.
December 1980*

July 1981
NTIS* PB82 133638.
March 31, 1983*

September 30, 1983*

March 1981
NTIS# PB82 131418.
April 1982*

March 31, 1983*
/
March 31, 1983*

September 28, 1983*

March 1982
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
12/2/80*
RS-81-004
7/31/81
RS-81-014/*.
4/7/83**



3/16/81**
RS-81-001
6/30/82
PB81-204383.
4/11/83**

4/7/83**



6/25/82
  (PM 15)
NTIS# PB82 243999.  RS82-0081
                    PB82-243999
*  RS or NTIS PB number not available.
** NTIS numbers not available.
                                                32

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                            REGISTRATION STANDARDS - ISSUED Cont'd
                                                September 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
EPTC

ETHION
  (PM 16)

ETHOPROP
  (PM 16)

ETHOXYQUIN
  (PM 25)

2 ETHYL If3 HEXANEDIOL(6-12)
  (PM 17)

FENAMINOSULF
  (PM 21)

FORMETANATE HYDROCHLORIDE
  (PM 12)

FUMARIN (COUMAFURYL)
  (PM 16)

GLEAN® (CHLOROSULFURON)
  (PM 25)

HEXAZINONE (VELPAR)
  (PM 23)

HYPOCHLORITE Salts
  (PM-32)
Herbicide

Insecticide


Nematicide


Growth Regulator


Insecticide


Fungicide


Insecticide


Rodent Toxicant
and Anticoagulant

Herbicide


Herbicide


Disinfectant
September 30, 1983*

December 1982*      12/23/82**
June 23, 1983*
March 1981*
 6/24/83**
 3/81
 RS-81-011**
June 1981            6/5/81
NTIS# PB81-234098.   RS-81-005

September 30, 1983*
September 16, 1983*  9/23/83**
September 1982       10/21/80**,
NTIS# PB81 123812.
September 1982.
February 1982.
January 13, 1983
 9/30/82**.
 4/27/82**
*  RS or NTIS PB number not available.
** NTIS numbers not available.
                                                33

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                              REGISTRATION STANDARDS -  ISSUED Cont'd
September 1983

CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
ISOPROPALIN
(PM 25)
MAGNESIUM PHOSPHIDE
(PM 16)
MCPA
(PM 23)
METALAXYL (RIDOMIL®)
(PM 21)
METHAMIDOPHOS (MONITOR®)
(PM 16)
METHIDATHION
(PM 12)
METHOMYL
(PM 12)
METHOPRENE
(PM 17)
METOLACHLOR
(PM 23)
MONURON
(PM 25)
TYPE OF
CHEMICAL
Herbicide
Insecticide
Herbicide
Fungicide
Insecticide
Insecticide
Insecticide
Insecticide
Herbicide
Herbicide
DATE OF
STANDARD
& NTIS NOS.
August 1981
NTIS# PB82 131293.
March 1982
NTIS# PB82 195777.
March 1982.
August 1981
NTIS# PB82 172297.
September 1982
January 13, 1983
September 1981
NTIS# PB82 180738.
February 1982*
September 1980*
NTIS# PB81 123820.
June 30, 1983*
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
8/5/81
RS-81-009
PB82-131293.
3/29/82
RS-82-006
PB82-195777.
6/30/82**.
8/31/81
RS-82-005
PB82-172297.
9/24/82**.
1/14/83
1/22/82
RS-82-001
3/31/82**.
9/30/80**
7/7/83**
*  RS or NTIS PB number not available.
** NTIS numbers not available.
                                                34

-------
                              REGISTRATION STANDARDS - ISSUED Cont'd
                                                  September 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
MONURON TCA
  (PM 25)

NALED
  (PM 16)

NAPHTHALENE
  (PM 16)
NAPHTHALENEACETIC ACID
  AND ITS SALTS
  (PM 25)

OBPA (10, 10'-
  OXYBISPHENOXARSINE)
  (PM 21)

PHOSALONE
  (PM 12)

PLANTPIN® (BUTOXICARBOXIME)
  (PM 12)
SULFUR
  (PM 22)

SULPROFOS (BOLSTAR)
  (PM 12)
Herbicide


Inseticide


Insecticide


Growth Regulator


Fungicide


Insecticide


Insecticide


Fungicide


Insecticide
June 30, 1983*
June 30, 1983*
September 1981
NTIS* PB82 139437,
August 1981
NTIS #PB82 131145
September 1981
NTIS* PB82 172271,
September 1981.
NTIS# PB82 131731
   /
September 1981
NTIS# PB82 177585,
December 1982*
7/7/83**
7/6/83*'
11/9/81
RS-81-016
PB82-139437,

8/18/81
RS-81-006
PB82-131145,

10/27/81
RS-82-003
PB82-172271,

9/18/81
RS-81-010**

9/30/81
RS-82-004
PB82-177585

12/29/82**
August 1981          8/10/81
NTIS# PB82 133646.   RS-81-008
*  RS or NTIS PB number not available.
** NTIS numbers not available.
                                                35

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                              REGISTRATION  STANDARDS  -  ISSUED ContM
                                                  September 1983

CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION

TEMEPHOS (ABATE)
(PM 16)

TERBACIL
(PM 25)
TERBUFOS
(PM 16)
TERRAZOLE
(PM 21)

WARFARIN
(PM 16)
TYPE OF
CHEMICAL

Insecticide



Herbicide
Insecticide

Fungicide


Rodent Toxicant &
Anticoagulant
DATE OF
STANDARD
& NTIS NOS.

August 1981
NTIS# PB82 140641.


June 4, 1982*
June 30, 1983*

September 1980
NTIS* PB81 126716.

August 1981
NTIS# PB82 140716.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
PB82-133646.
9/25/81
RS-81-018
PB82-140641.

6/4/82**
6/30/83**

9/30/80
OPP-80-525
PB81-126716.
10/26/81
RS-81-019
ZINC PHOSPHIDE
  (PM 16)
Rodent Toxicant and
Anticoagulant
June 1982*
                                                                            PB82-140716
6/23/82**.
*  RS or NTIS PB number not available
** NTIS numbers not available
                                                36

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                            DATA CALL IN — STATUS OF CHEMICALS
                                                                         September 1983
The following chemical clusters are being processed through Data Call in (DCI).
These clusters are the same as described in the Federal Register notice on
November 14, 1980 (45 FR 75488), except that the chemicals now in Registration Standard
development or in the RPAR process are omitted.  The status of these clusters and the
chemicals are as follows.

DCI Cluster #1 consists of insecticides used on corn, alfalfa and sorghum (1-2)

     Chemical            .           Status
     Bufencarb
     Carbofuran
     Carbophenothion
     Chlorpyrifos
     Disulfoton
     Ethoprop
     Fensulfothion
     Fonofos
     Landrin (Broot)
     Phorate
     TEPP
     Terbufos
     Trichlorfon
Decision reached - cancelled/suspended.
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated
Decision reached - chronic data being generated
Decision reached - -chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - suspended.
Decision reached - temporary data waiver.
Decision reached - chronic data base complete.
"Letter being drafted" — the Agency is investigating the available chronic studies and
discussing the findings with registrants.

"Letter issued (date)" — The notice/notification or equivalent was issued to indicate
existing chronic data gaps.

"Decision reached" — The Agency has evaluated all the responses from registrants reques-
ting exemptions, waivers, commitments,  offers to cost share, cancellations, suspensions,
etc. and has issued final decisions on the data required and status of all registrations
containing the chemical.  The terms "chronic data being generated" or "chronic data
waiver or deferral" are self explanatory.  "Chronic data base complete" may mean that the
data were available, recently submitted,  or certain data requirements have been waived.
The terms "cancelled", "suspended", "no current registrations" mean that there are no
known active registrations of the chemicals.  The term "Defer requirements to Standard"
means that the standard is planned to be developed within two years hence and the chronic
requirements will be addressed in the standard.
                                                37

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                                                                      September 1983
                        DATA CALL IN — STATUS OF CHEMICALS cont'd

Data Call In Cluster |2 consists of insecticides used on citrus and grapes (1-4).

       Chemical                    Status
    Chlorobenzilate
    Cryolite
    Dimethoate
    Dioxothion
    Ethion
    Formetanate hydrochloride
    Naled
    Tetradifon

Data Call In Cluster #3 consists
wheat and tobacco (1-1).

    Aldicarb
    Bollex
    Chlordimeform
    Chlordimeform hydrochloride
    Demeton
    Dimilin
    Endrin
    Fenvalerate
    Gossyplure
    Grandlure
    Heliothis virus
    Methyl Parathion
    Monocrotophos
    Parathion
    Permethrin
    Phosphamidon
  Decision
  Decision
  Decision
  Decision
  Decision
  Decision
  Decision
  Decision
reached
reached
reached
reached
reached
reached
reached
reached
chronic data
chronic data
chronic data
chronic data
chronic data
chronic data
chronic data
suspended.
being generated.
deferred.
base being generated,
being generated.
being generated.
deferred.
being generated.
of insecticides used on cotton, soybeans, peanuts,
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Decision reached - chronic data
  Letter issued 11/14/81.
  Decision reached - chronic data
  Decision reached - chronic data
                       being generated,
                       base complete.
                       base complete.
                       base complete.
                       being generated,
                       base complete.
                       base complete.
                       base complete.
                       base complete.
                       base complete.
                       base complete.
                       being generated,
                       being generated,

                       base complete.
                       being generated,

-------
                        DATA CALL IN — STATUS OF CHEMICALS cont'd
                                                                         September 1983
Data Call In Cluster #4 consists of herbicides used on corn (H-2).
   Alachlor
   Atrazine
   Butylate
   Cyanazine
   Cyprazine
   Dicaraba
   EPTC
   Simazine
   TCBC
Decision reached - chronic data base complete.
Letter issued 7/26/82
Decision reached - chronic data being generated.
Letter issued 7/12/82.
Decision reached - Suspension/Cancellation.
Letter issued 9/28/82.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - cancelled/suspended.
Data Call In Cluster #5 consists of herbicides used on soybeans, cotton, peanuts and
alfalfa (H-3).
   Acifluorfen
   Bentazon (and sodium form)
   2,4-DB
   Dichlofop methyl
   Dinitramine
   Dipropetryn
   DSMA
   EGT
   Fluchloralin
   Glyphosate isopropylamine salt
   Metribuzin
   Naptalam
   Nitralin
   Norflurazon
   Oryzalin
   Oxyfluoren
   Pendimethalin
   Perfluidone
   Profluralin
   Pronamide
   Propachlor
   Vernolate
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Letter issued 10/22/82.
Decision reached - chronic data base complete.
Decision reached - chronic data base to be generated,
Letter issued 3/31/83.
Letter issued 8/18/82.
Decision reached - cancelled.
Letter issued 12/1/82.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - Defer requirements to standard.
Decision reached - cancelled.
Letter issued 7/25/83.
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Letter issued 9/7/82.
Decision reached - No added data required.
Decision reached - cancelled.
Decision reached - chronic data being generated.
Letter issued 1/19/83
Decision reached - chronic data being generated.
                                                39

-------
                        DATA CALL IN — STATUS OF CHEMICALS cont'd

Data Call in Cluster #6 consists of fungicides used on vegetables (F-3).
                                                                        September 1983
Anilazine
Calcium Cyanamide
DCNA
Hexachlorophene
Triadiraefon
Decision reached - Defer requirements to standard.
Letter issued 8/11/83.
Decision reached - Defer requirements to standard.
Letter deferred.
Decision reached - chronic data base complete.
Special Data Call In Fungicide Project consists of certain large volume fungicides which
will be processed through Data Call In and subjected to comparative risk analysis.
Captafol
Chlorothalonil
Copper (Bordeaux mixture)
Copper Carbonate
Copper Naphthenate
Copper Oxide
Copper Oxychloride
Copper Quinolinolate
Copper Sulfate Basic
Copper Sulfate Monohydrate
Dinocap
Dodine
Ferbam
Folpet
Thiram
Decision reached - chronic
Letter issued 9/14/81.
Decision feached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Letter issued 9/4/81.
Letter issued 9/4/81.  '
Decision reached - chronic
data being generated,

data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
data being generated,
data base complete.
data base complete.
Special Data Call In Fumigant Project.
listed above but for fumigants.
    Same as Special Data Call In Fungicide Project
Carbon disulfide
Ethylene dichloride
Methyl Bromide
Decision reached - time extension on initiating studies,
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.

-------
                         DATA CALL IN — STATUS OF CHEMICALS COnt'd
                                                                        September 1983
                                     Letter issued 3/16/83
RPAR Decision Data Call In
      Benomyl
      EBDC's
        Amobam
        Mancozeb
        Maneb
        Metiram
        Nabam
        Zineb
      Piperonyl Butoxide
      TrefIan

R-7  Wood preservatives for industrial, commercial and marine use.

      Potassium bifluoride           Decision reached - Defer requirements to standard.

F-5  Fungicides used as seed treatments
Letter
Letter
Letter
Letter
Letter
Letter
Letter
Letter
issued
issued
issued
issued
issued
issued
issued
issued
1/83.
1/83.
1/83.
1/83.
1/83.
1/83.
9/30/82.
8/25/82.
      Chloronitropropane
      Fenaminosulf
      Hexachlorobenzene
                                     Decision reached - Cancelled/discontinued.
                                     Decision reached - Defer requirements to standard.
                                     Decision reached - Letter deferred
R-ll Preservatives, disinfectants, slimicides, unclassified uses.

      Abietylamine
      Chromic acid
      Chlorobenzene
      Dowicil A-40
      Dowicide 31,32
      Hexylene glycol
      Lime
      Nitrapyrin
      Omad i ne-sod i urn
      Potassium iodate
      Potassium permanganate
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
- No
- No
- No
- NO
- No
- No
- No
- NO
- No
- NO
- No
added
added
added
added
added
added
added
added
added
added
added
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
data
data
data
data
data
data
data
data
data
data
data
needed
needed
needed
needed
needed
needed
needed
needed
needed
needed
needed
now
now
now
now
now
now
now
now
now
now
now
                                                 41

-------
                       DATA CALL IN —STATUS OF CHEMICALS cont'd
                                                                      September 1983
1-3  Insecticides used on fruit and nut trees excluding citrus and grapes.
      Azinphos methyl
      Chloropropylate
      Cyhexatin
      Dormant oil
      Diazinon
      2-naphthol
      Ovex
      Phosmet
      Propargite
      Tetrasul
      Vendex
Decision reached - chronic data base complete.
Decision reached - cancelled/discontinued.
Letter issued 6/17/83.
Decision reached - no current registration.
Letter issued 2/18/83.
Decision reached - no added chronic data needed,
Decision reached - cancelled/discontinued.
Letter issued 6/20/83.
Decision reached - chronic data base complete.
Letter issued 7/26/83.
Letter issued 8/6/83.
H-4  Herbicides used on sorghum, rice and small grains.
       Barban
       Bromoxynil
       Butachlor
       Difenzoquat
       Methazole
       Molinate
       Oxadiazon
       Propanil
       Picloram
       Propazine
       Terbutryn
       Triallate
Letter issued 8/26/83.
Letter issued 1/19/83.
Decision reached - cancelled/discontinued
Letter issued 8/4/83.
Decision reached - chronic data deferred.
Letter issued 8/31/83.
Decision reached - defer requirements to Standard
Letter issued 7/20/83
Decision reached - defer rqmts. to standard.
Decision reached - chronic data base complete.
Letter being drafted.
Letter being drafted.

-------
                       DATA CALL IN — STATUS OF CHEMICALS cont'd
                                                                        September 1983
1-5  Insecticides used on vegetables.

      Bacillus thuringiensis
      Malathion
      Methoxychlor
      Mevinphos
      Nicotine
      Nicotine sulfate
      Oxamyl
      Oxydemeton methyl
      Pirimicarb
      Pirimiphos ethyl
      Rotenone
      Ryanodine
      Sabadilla alkaloids
Decision reached - chronic data base complete.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter issued 8/30/83.
Letter issued 8/30/83.
Decision reached - chronic data base complete.
Letter issued 8/11/83.
Decision reached - cancelled/discontinued.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter issued 8/22/83
H-5 Herbicides used on citrus,  tree fruits,  nuts,  and sugar cane.
      Ametryn
      Asulam
      Dichlobenil
      Hexazinone
      Napropamide
      Paraquat
Letter issued 8/15/83.
Decision reached - chronic data base complete.
Letter issued 8/18/83.
Decision reached - Defer rqmts. to standard.
Letter issued 8/30/83.
Decision reached - chronic data base complete.
H-9  Herbicides used on vegetables and tobacco.
      Bisethylxanthogen
      CDAA
      Chlorpropham
      Diphenamid
      Endothall
      Nitrofen
      Prometryn
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
                                                43

-------
                      DATA CALL IN — STATUS OF CHEMICALS cont'd

F-2   Fungicides used on walnuts,  pecans,  almonds,  apples, pears,
      peaches, cherries, plums, prunes,  and  grapes.
                                                                        September 1983
      Ammonium Polysulfide
      Dithianon
      2,2- Dithiobisbenzothiazole
      Fentin hydroxide
      Glyodin
      Oxythioqu inox
      Sodium Polysulfide
      Streptomycin
      Ziram
Letter issued 8/6/83.
Letter being drafted.
Letter being drafted.
Decision reached - Defer rqmts. to standard
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
H-6   Herbicides used on sugar beets,  beans and peas.
      Cycloate
      Dalapon
      Desmedipham
      Diallate
      Dinoseb
      Ethofumesate
      MCPB
      Pebulate
      Phenmedipham
      Propham
      Pyrazon
      Sodium TCA
Letter being drafted.
Letter being drafted.
Letter being drafted.
Decision reached - Defer rqmts. to standard
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter issued 9/12/83.
Letter being drafted.
Letter being drafted.
Letter issued 8/30/83.
H-7   Herbicides used on drainage ditches,  rights of way, forestry
      and ponds.
      Acrolein
      Amitrol
      Dichlorprop
      Diquat
      Fenac
      Karbutilate
Letter
Letter
Letter
Letter
Letter
Letter
being
being
being
being
being
being
drafted.
drafted.
drafted.
drafted.
drafted.
drafted.

-------
                       DATA CALL  IN  —  STATUS  OF  CHEMICALS  cont'd
                                                                        September 1983
       MAMA
       MSMA
       Prometon
       Trichlopyr
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter issued 8/22/83.
                                  Letter being drafted.
1-12   Insecticides used  as  mosquito larvicides.
       Dimethrin
       Fenthion
       Kerosene
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
1-6
Insecticides used on livestock and domestic animals.
       Benzyl  Benzoate
       Bomyl
       Bone oil
       Butonate
       Butoxy  Polypropylene  glycol
       Chlorfenvinphos
       Crotoxyphos
       Crufornate
       Dichlorvos
       Diisobutyl Phenoxyethanol
       Diphenylamine
       Famphur
       Lindane
       Linseed Oil
       Muscalure
       Phenothiazine
       Piperazine dihydrochloride
       Tabutrex
       Tetrachlorvinphos
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter issued 8/12/83.
                                  Letter issued -  3/22/83
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter issued 9/7/83.
                                  Letter being drafted.
                                                45

-------
                                     Page

Abate® see Temephos
Abietylamine  S #004101                41
  CAS #51344-60-6
Acephate  S #103301                    27
  CAS #30560-19-1
Acifluorfen S #114401, 114402, 114403  39
  CAS # 50594-66-6
      sodium salt 62476-59-9
      ethyl ester 77207-01-3
Acrylonitrile  S #000601                6
  CAS #107-13-1
Acrolein S #000701                     44
  CAS #107-02-8
Alachlor  S #090501               27 & 39
  CAS #15972-60-8
Alar® see Daminozlde
Aldicarb  S #098301, 110801       27 & 38
  CAS #116-06-3
Aldrin/Dieldrin  S #45101/45001         8
  CAS #309-00-2—60-57-1
Aliette  S #123301                     30
  CAS # 39148-24-8
Aluminum phosphide  S #066501          30
  CAS #20859-73-8
Ametryn  S #080801                     43
  CAS #834-12-8
4-Aminopyridine  S #069201             30
  (Avitrol®)
  CAS #504-24-5
Amitraz  S #106201, 572200        16 & 25
  CAS #33089-61-1
Amitrole  S #004401               27 & 44
  CAS #61-82-5
Ammonium polysulfide  S #076701        44
  CAS #9080-17-5
Ammonium sulfamate  S #005501          30
  CAS #7773-06-0
                                                 INDEX
Amobam  S #014502
  CAS #3566-10-7
Anilazine  S #080811
  CAS #101-05-3
Arsenicals  S # Multiple
  CAS # Multiple
Arsenic trioxide  S #007001
  CAS #1327-53-3
Aspon®  S #079101
  CAS #3244-90-4
Asulam  S #106901
  CAS #3337-71-1
Atrazine  S #080803
  CAS #1912-24-9
Avitrol®  see 4-Aminopyridine
Azinphos methyl  S #058001
  CAS #86-50-0
Bacillus thuringiensis  S #006401
  CAS #68038-71-1
Barban  S #017601
  CAS #101-27-9
Barium Metaborate  S #011101
  CAS #13701-59-2
Benomyl  S #099101
  CAS #17804-35-2
Bentazon and sodium form
  S #275200, 103901
  CAS #25057-89-0? 50723-80-3
Benzene  S #008801
  CAS #71-43-25-2
Benzyl benzoate  S #009501
  CAS #120-51-4
BHC  S #008901
  CAS # mixed isomers 608-73-1
  alpha 319-84-6
  beta 319-85-7
  gamma 58-89-9 (See Lindane)
  delta 319-86-8
27
30
Page

  41

& 40

  27

   6

  30

  43

& 39


  42
16,27
27
42
30
& 41
& 39
      6

     45

      6

-------
                                     Page

  epsilon 6108-10-7
  zeta 6108-11-8
  eta 6108-12-9
Bidrin® see Dicrotophos
Bifenox S 1104301,  285200               30
  CAS #42576-02-3
Bisethylxanthogen  S ,#086501           43
  CAS #502-55-6
BKLFI-2  S #046924                      30
  CAS #82010-75-1
Bollex  S #118501                      38
  CAS #4175-47-7
Bolstar®  see also  Sulprofos           31
Bomyl  S #084201                       45
  CAS #122-10-1
Bone Oil  S #010801                     45
  CAS #8001-85-2
Boric acid  S #011001                   31
  CAS #10043-35-3
Bromacil & salts S  #012301,02,03,04    31
  CAS #314-40-9
  dimethylamine bromide #69484-13-5
  lithiumbromacil #53404-19-6
  sodium bromcil #69484-12-4
Bromoxynil  S #035301                   42
  CAS #1689-84-5
BTC 2125  S #'s 069104,069111          25
  CAS #'s 53516-76-0,  8045-21-4
Bufencarb  S #059301                   37
  CAS #8065-36-9
Butachlor  S #112301                   42
  CAS #23184-66-9
Butonate  S #035701                     45
  CAS #126-22-7
Butoxicarboxime  see Plantpin®
Butoxy polypropylene glycol  S #011901 45
  CAS #9007-07-2
                                     Page
Butylate  S #041405               31
  CAS #2008-41-5
Cacodylic acid & salts  S #012501
  CAS #75-60-5
  Sodium cacodylate 124-65-2
Cadmium  S #021001, 02, 05;
         012901, 02, 236200,
         012903, 04, 05; 064601
  CAS # for following compounds
  anilocadmium dilactate 19651-91-3
  cadmium carbonate 513-78-0
  cadmium chloride 10108-64-2
  cadmium oxide 1306-19-0
  cadmium succinate 141-00-4
  cadmium sebacate 4476-04-4
  cadmium sulfate 10124-36-4
Calcium cyanamide  S #014001
  CAS #156-62-7
Captafol  S #081701
  CAS #2425-06-1
Captan  S #081301
  CAS #133-06-2
Carbaryl  S #056801
  CAS #63-25-2
Carbofenothion  S #058102
  CAS #786-19-6
Carbofuran  S #090601
•  CAS #1563-66-2
Carbon disulfide  S #016401
  CAS #75-15-0
Carbon tetrachloride  S #016501
  CAS #56-23-5
Carbophenothion  S #058102
  CAS #786-19-6
Carboxin (Vitavax®)  S #090201
  CAS #5234-68-4
CDAA  S #019301
  CAS #93-71-0
& 39

  10

27
1
10

27


27


40
& 40
& 25
S, 27
27
& 37
40
1
& 37
31
43

-------
        Page
           8
Chloramben S #029901,  02,  03,  04,       31
              05, 06
  CAS #133-90-4
Chloranil S #079301                     6
  CAS #118-75-2
Chlordane/Heptachlor
  chlordane  S #058201
  CAS #57-74-9 (cp)
       12789-03-6 (tech)
  CAS #76-44-8
  heptachor  S #044801
    CAS #76-44-8
Chlordecone (Kepone) S #027701
  CAS #143-50-0
Chlordimeform  S #059701
  CAS #6164-98-3
Chlordimeform hydrochlorlde
  CAS #19750-95-9
Chlorfenvinphos  S #084101
  CAS #470-90-6
Chlorobenzene  S #056504
  CAS #108-90-7
Chlorobenzilate  S #028801
  CAS #510-15-6
Chloroform   S #020701
  CAS #67-66-3
Chloroneb   S #027301
  CAS #2675-77-6
Chloronitropropane  S #011302
  CAS #2425-66-3
Chloropicrin  S #081501
  CAS #76-06-2
Chloropropylate  S #026801
  CAS #5836-10-2
Chlorothalonil  S #081901         27 S. 40
  CAS #1897-45-6
Chlorpropham  S #018301
  CAS #101-21-3
       6 & 8
          38

S #059702 27 &
            38
          45

          41

 17, 27 S, 38

          11

          31

          41

          31

          42
          43
Chlorpyrifos  S #059101
  CAS #2921-88-2
Chromic acid  S #021101
  CAS #7738-94-5
Coal tar  S #022003
  CAS #8007-45-2
Copper acetoarsenite  S #022601
  CAS #12002-03-8
Copper arsenate (Basic)  S #271300
  CAS # 16102-92-4
Copper (bordeaux mixture)  S #
  CAS #8011-63-0
Copper carbonate  S #022901
  CAS #12069-69-1
Copper naphthenate  S #023102
  CAS #1338-02-9
Copper oxide  S #025601
  CAS #1317-38-0 & 1317-39-1
Copper oxychloride  S #023501
  CAS #8012-69-9
Copper quinolinolate  S #024002
  CAS #10380-28-6
Copper sulfate basic  S #024401
  CAS #1344-73-6
Copper sulfate monohydrate
  S #024402
  CAS #10237-72-6
Coumafuryl  see Fumarin®
Coumaphos  S #036501
  CAS #56-72-4
Creosote  S #025004
  CAS #8021-39-4
Crotoxyphos  S #058801
  CAS #7700-17-6
Crufomate  S #012101
  CAS #299-86-5
Cryolite   S #075101              31
  CAS #15096-52-3

27










25
26
Page
& 37
41
1
6
6
40
40
40
40
40
40
& 40
& 40
  31

   2

  45

  45

& 38

-------
                                     Page
Cyanazine  S #100101              27
  CAS #21725-46-2
Cycloate  S #041301
  CAS #1134-23-2
Cyclohexiraide  S #043401
  CAS #66-81-9
Cyhexatin  S #101601              25
  CAS #13121-70-5
Cyprazine  S #100401
  CAS #22936-86-3
Dalapon  S #'s 028901,2,3,4
  CAS #75-99-0; 127-20-8; 29110-22-3
       83542-87-4; 83542-88-5
Daminozide (Alar®)  S #035101
  CAS #1596-84-5
Dasanit  see Fensulfothion
2,4-DB  S #030801
  CAS #94-82-6
DBCP  S #011301
  CAS #96-12-8
DCNA  S #031301
  CAS #99-30-9
ODD  S #029101
  CAS #72-54-8
DDT  S #029201
  CAS #50-29-3
Deet  S #080301
  CAS 134-62-4
Demeton  S #057601
  CAS 8065-48-3
Desmedipham  S #104801
  CAS #13684-56-5
Dialifor  S #102501
  CAS #10311-84-9
Diallate S #078801             :
  CAS #2303-16-4
      cis #17708-58-6
      trans #17708-57-5
& 39

  44

  31

& 42

  39

  44


  28

8 &
28 &



28 &


32 &
39
17
40
8
8
32
38
44
32
44
                                                  Page
     42
     25
32 & 39
Diazinon  S #057801
  CAS #333-41-5
Dibromosalicylanilide  S #077402
  CAS #87-12-7
Dicamba S #029801, 02, 03,
              04, 05, 06
  CAS #1918-00-9; 2300-66-5;
       25059-78-3; 53404-28-7
       53404-29-8; 1982-69-0
Dichlobenil  S #027401
  CAS #1194-65-6
Diclofop methyl  S #110902
  CAS # 51338-27-3
Dichlone   S #029601
  CAS #117-80-6
Dichlorprop  S #031401
  CAS #120-36-5
Dichlorvos  S #084001
  CAS #62-73-7
Dicofol  see Kelthane®
Dicrotophos S #035201
  CAS #141-66-2
Dieldrin  see Aldrin/Dieldrin
Difenzoquat  S #106401
  CAS #43222-48-6
Diflubenzuron (Dimilin) S #108201  11 &25
  CAS #35367-38-5
Diisobutyl phenoxyethanol  S #001504   45
  CAS #121-54-0
Dimethoate  S #035001
  CAS #60-51-5
Dimethrin  S #034101
  CAS #70-38-2
Dimilin  S #108201
  CAS #35367-38-5
Dinitramine  S #102301
  CAS #29091-05-2
     43
     39
     32
                                                    44
                                               11 & 45
                                                    32
                                                    42
                                           18,  32 & 38
                                                    45
                                                    38
                                                8 & 39

-------
                                     Page

Dinocap  S #036001                     40
  CAS #39300-45-3
Dinoseb  S #'s 037511,2,3,4;037505,6   44
  CAS #88-85-7; 6420-47-9;  8048-12-2;
       35040-03-0; 6365-83-9;
       53404-43-6; 2813-95-8
Dioxathion  S #037801             32 & 38
  CAS #78-34-2
Diphenamid  S #036601                  43
  CAS #957-51-7
Diphenylamine  S #038501               45
  CAS #122-39-4
Dipropetryn  S #104401            25 & 39
  CAS #4147-51-7
Diquat dibromide  S #032201            44
  CAS #85-00-7
Disulfoton  S #032501             28 & 37
  CAS #298-04-4
Dithianon  S #099201                   44
  CAS #3347-22-6
2,2-Dithiobisbenzothiazole S #009202   44
  CAS #120-78-5
Diuron  S #035505                      32
  CAS #330-54-1
Dodine  S #044301                      40
  CAS #2439-10-3
Dormant oil  S # none                  42
  CAS # none
Dowicide 31:32  S #062208,  10          41
  CAS #607-12-5
Dowicil A-40 S #102801                 41
  CAS #38827-35-9
DSHA  S #013802                        39
  CAS #144-21-8
EBDC's  S #014502,3,4,5,6;  014601  19 &41
  CAS #lll-54-6(Parent); 3566-10-7;
   142-59-6; 8018-01-7; 12427-38-2;
   12122-67-7; 9006-42-2
                                     Page

  see  amobam, maneb,  nabam,
       mancozeb, metiram, zineb
EGT S #042201                          39
  CAS #2514-53-6
Endosulfan S #079401                   32
  CAS #115-29-7-1
Endothall  S #'s 038901,2,3,4,5,6,7;   43
  CAS #145-73-3; 2536-26-7;  129-67-9;
       2164-07-0; 2536-27-8
Endrin  S #041601            8,19,25 & 38
  CAS #72-20-8
EPN  S #041801                     2 & 25
  CAS #2104-64-5
EPTC  S #041401                   33 & 39
  CAS #759-94-4
Erbon  S #028701                        6
  CAS #136-25-4
Ethion  S #058401                 33 & 38
  CAS #563-12-2
Ethofumesate  S #110601                44
  CAS #26225-79-6
Ethoprop  S #041101               33 & 37
  CAS #13194-84-4
Ethoxyquin  S #055501                  33
  CAS #91-53-2
2-Ethyl-l,3-hexanediol S #041001       33
  CAS #94-96-2
Ethylene dibromide  S #042002          20
  CAS #106-93-1
Ethylene dichloride  S #042003         40
  CAS #107-06-2
Ethylene oxide  S #042301               2
  CAS #75-21-8
Famphur  S #059901                     45
  CAS #52-85-7
Fenac  S #082601                       44
  CAS #85-34-7

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                                     Page

Fenaminosulf  S #034201           33 & 41
  CAS #140-56-7
Fensulfothion   S #032701         28 & 37
  CAS #115-90-2
Fenthion  S #053301                    45
  CAS #55-38-9
Fentin hydroxide  S #.083601            44
  CAS #76-87-9
Fenvalerate  S #109301                 38
  CAS #51630-58-1
Ferbam  S #034801                      40
  CAS #14484-64-1
Fluchloralin S #108701            28 & 39
  CAS #33245-39-5
Folpet  S #081601                      40
  CAS #133-07-3
Fonofos  S #041701                28 & 37
  CAS #944-22-9
Formetanate hydrochloride         33 & 38
  S #097301
  CAS #23422-53-9
Fumarin® (Coumafuryl) S #086001        33
  CAS #117-52-2
Glean  S #118601                       33
  CAS #64902-72-3
Glyodin  S #043601                     44
  CAS #556-22-9
Glyphosate isopropylamine
  salt  S #103601                 25 & 39
  CAS #38641-94-0
Goal  S #111601                        20
  CAS # 42874-03-3
Gossyplure®  S #114101, 02             38
  CAS # 53042-79-8, 52207-99-5
Grandlure®  S #112401, 02, 03, 04      38
  CAS #11104-05-5
HCL  S #045901                         25
  CAS #7647-01-0
                                     Page

Heliothis virus  S #107301        28 & 38
  CAS # none
Heptachlor  see Chlordane Heptachlor
Hexachlorobenzene  S #061001           41
  CAS #118-74-1
Hexachlorophene  S #044901             40
  CAS #70-30-4
Hexazinone (Velpar®)  S #107201   33 & 43
  CAS #51235-04-2
Hexylene glycol  S #068601        25 & 41
  CAS #107-41-5
Hyamine 3500  S #069105                25
  CAS # None
Hypochlorites  S #014701, 02, 03       33
  CAS # for following compounds
  sodium 7681-52-9
  calcium 7778-54-3
  lithium 13840-33-0
Inorganic arsenicals               3 & 27
  S #006801, 02 006901, 007001
  CAS # for following compounds
  arsenic acid 1327-52-2 & 7778-39-4
  arsenic pertoxide 1303-28-2
  arsenic trioxide 1327-53-3
  sodium arsenate 7631-89-2, 10103-60-3,
  13464-38-5 & 35794-26-4
  ammonium arsenite 58829095-1
  sodium pyroarsenate 13464-42-1
  lead arsenate (basic) 3687-31-8
  lead arsenate 7645-25-2, 7784-40-9 &
  10102-48-4
  calcium arsenate 7778-44-1
  sodium arsenite 7784-46-5
  copper acetoarsenite 12002-03-8
Isocyanurates  S #081401,2,3,4,5,6,7    7
  CAS #126-25-4
  isocyanuric acid 108-80-5
  isocyanuric chloride 87-90-1

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                                     Page

  potassium dichloroisocyanurate 2244-21-5
  sodium dichloroisocyanurate 2893-78-9
  isocyanuric dichloride 2782-57-2
  isocyanuric dichloride,
    dihydrate 515 80-86-0
  ACL-66  30622-37-8
Isopropalin  S #10020.1                 34
  CAS #33820-53-0
Karbutilate  S #097401                 44
  CAS #4849-32-5
Kelthane® (Dicofol)  S #010501         28
  CAS #115-32-2
Kepone  see Chlordecone
Kerosene  S #063501                    45
  CAS #8008-20-6
Landrin  S #102401, 02                 37
  CAS #2686-99-9
Lime  S #075604                        41
  CAS #1305-78-8
Lindane  S #009001                21 & 45
  CAS #58-89-9
Linuron  S #035506                     28
  CAS #330-55-2
Linseed Oil  S #031603                 45
  CAS #8001-26-1
Magnesium phosphide S #066504, 218100  34
  CAS #12057-74-8
Malathion  S #0577                     43
  CAS #121-75-5
Maleic hydrazide  S #051501, 02, 03    12
  CAS #123-33-1
MAMA  S #013808                        45
  CAS #2321-53-1
Mancozeb  S #014504                    41
  CAS #8018-01-7
Maneb  S #014505, 005050               41
  CAS #12427-38-2
                                                                                       Page
MCPA  S #030501,2,3; 030553, 56, 62;   34
         030563, 66; 030510, 11, 12,
         13, 14, 15, 16
  CAS #94-74-6; 3653-48-3; 5221-16-9;
    6365-62-4; 20405-19-0; 42459-68-7;
    42459-69-8; 42459-70-1; 42459-71-2
    2039-46-5; 19480-43-4; 1713-12-8;
    1713-11-7; 26544-20-7; 2698-40-0
MCPB  S #019201                        44
Metalaxyl (Ridomil®) S #113501         34
  CAS #57837-19-1
Methamidophos (Monitor®)  S #101201    34
  CAS #10265-92-6
Methanearsonates  S #013802, 03, 04,   12
                  05, 06, 07, 08
  CAS # for following compounds
  calcium acid 5902-95-4
  calcium methanearsonate 5902-97-6
  MAMA 2321-53-1
  MSMA 2163-80-6
  DSMA 144-21-8
  octyl ammonium 6379-37-9
  docecyl ammonium 53404-47-0
Methazole  S #106001                   42
  CAS #20354-26-1
Methidathion  S #100301                34
  CAS #950-37-8
Methomyl  S #090301, 549400            34
  CAS #16752-77-5
Methoprene  S #105401, 549500          34
  CAS #40596-69-8
Methoxychlor  S #034001                43
  CAS #72-43-5
Methyl bromide  S #053201              40
  CAS #74-83-9
Methyl parathion  S #053501            38
  CAS #298-00-0

-------
                                     Page
Metiram  S 1014601
  CAS #9006-42-2
Metolachlor  S #108801, 288700
  CAS #15972-60-8
Metribuzin  S #101101
  CAS #21087-64-9
Mevinphos  S #015801
  CAS #7786-34-7
Mirex  S #039201
  CAS #2385-85-5
Molinate  S #041402
  CAS #2212-67-1
Monitor® .see Methamidophos
Monocrotophos  S #058901
  CAS #6923-22-4
Monuron  S #035501
  CAS #150-68-5
Monuron trichloroacetate S #035502
  CAS #140-41-0
MSMA  S #013803
  CAS #2163-80-6
Muscalure  S #103201
  CAS #27519-02-4
Nabam  S# 014503
  CAS #142-59-6
Naled  S #034401
  CAS #300-76-5
Napropamide  S #103001
  CAS #15299-99-1
Naptalam  S # 030701, 02, 03
  CAS #132-66-1
Napthalene  S #055801
  CAS #91-20-3
Napthaleneacetic acid
       03,  04, 07, 08
  CAS #86-87-3
2-napthol  S #010301
  CAS #135-19-3
                41
                34
           25 & 39
                43
                42
           25 & 38
            7 & 34
                35
                45
                45
                41
        12,35 & 38
                43
           26 & 39
S #056001, 02,
055801, 589300
                35
35
                42
                                     Page

Neomycin sulfate  S #006313            26
  CAS #1405-10-3
Nicotine  S #056702                    43
  CAS #54-11-5
Nicotine sulfate  S #056703            43
  CAS #65-30-5
Nitralin  S #037601                    39
  CAS #4726-14-1
Nitrapyrin  S #069203             26 & 41
  CAS #1929-82-4
Nitrofen  S #038201                    43
  CAS #1836-75-5
Norflurazon  S #105801            28 & 39
  CAS #27314-13-2
OBPA (10, 10' Oxybisphen
        oxarsine)  S #012601      13 & 35
  CAS #58-36-6
Omadine-sodium  S #088004         26 & 41
  CAS #15922-78-8
OMPA  S #058601                         7
  CAS #152-16-9
Orthene®  see Acephate
Oryzalin  S #104201               26 & 39
  CAS #19044-88-3
Ovex  S #020201                        42
  CAS #80-33-1
Oxadiazon  S #109001                   42
  CAS #19666-30-9
Oxamyl  S #103801                      43
  CAS #23135-22-0
10,10 Oxybisphenoxarsine  see OBPA
Oxydemeton methyl  S #058702           43
  CAS #301-12-2
Oxyfluorfen  S #111601                 39
  CAS #42874-03-3
Oxythioquinox  S #054101               44
  CAS #2439-01-2

-------
                                     Page

Paraquat  S 1061612               13 & 43
  CAS #4685-14-7
Parathion  S #057501              26 & 38
  CAS #56-38-2
PCNB  S #056502                        21
  CAS #82-68-8
Pebulate  S #041403  .                  44
  CAS #1114-71-2
Pendiraethalin  S #108501          28 & 39
  CAS #40487-42-1
Pentachlorophenol  S #063001, 02,       3
                 03,08, 09, 10, 11
  CAS #87^-86-5
  sodium pentachlorophenate #131-52-2
  potassium      "          #7778-73-6
Perfluidone  S #108001, 02             39
  CAS #37924-13-3
Permethrin  S #109701                  38
  CAS #52645-53-1
Perthane  S #032101                     7
  CAS #72-56-0
Phenarsazine chloride  S #063901        7
  CAS #578-94-9
Phenmedipham  S #098701                44
  CAS #13684-63-4
Phenothiazine  S #064501               45
  CAS #92-84-2
Phorate  S #057201                28 & 37
  CAS #298-02-2
Phosalone  S #097701                   35
  CAS #2310-17-0
Phosmet  S #059201                     42
  CAS #732-11-6
Phosphamidon  S #018201                38
  CAS #13171-21-6
Picloram  S #005101               28 & 42
  CAS #1918-02-1
                                     Page

Piperazine dihydrochloride  S #067401  45
  CAS #142-64-3
Piperonyl butoxide  S #067501     13 & 41
  CAS #51-03-6
Pirimicarb  S #106101                  43
  CAS #23103-98-2
Pirimiphos-ethyl  S #108101            43
  CAS #23505-41-1
Plantpin® (butoxicarboxim) S #113001   35
  CAS #39196-18-4
Potassium bifluoride  S #075203   28 & 41
  CAS #7789-29-9
Potassium bromide  S #013903           28
  CAS #7758-02-3
Potassium hydroxide  S #075602         26
  CAS #1310-58-3
Potassium iodate  S #075703       28 & 41
  CAS #7758-05-6
Potassium permanganate  S #068501 26 & 41
  CAS #7722-64-7
Profluralin  S #106601                 39
  CAS #26399-36-0
Prometon  S #080804                    45
  CAS #1610-18-0
Prometryn  S #080805                   43
  CAS #7287-19-6
Pronamide  S #101701              21 & 39
  CAS #23950-58-5
Propachlor  S #019101             29 & 39
  CAS #1918-16-7
Propanil  S #028201                    42
  CAS #709-98-8
Propargite  S #097601                  42
  CAS #2312-35-8
Propazine  S #080808                   42
  CAS #139-40-2
Propham  S #047601                     44
  CAS #122-42-9

-------
Pyrazon  S #069601
  CAS #1698-60-8
Ridomil®  see Metalaxyl
Ronnel  S #50301
  CAS #299-84-3
Rotenone  S #071003
  CAS #83-79-4
Ryanodine  S #071502
  CAS #15662-33-6
Sabadilla alkaloids  S #002201
  CAS #8051-02-3
Safrole  S #097901
  CAS #94-59-7
Simazine  S #080807
  CAS #122-34-9
Sodium arsenite  S #013603
  CAS #7784-46-5
Sodium bentazon  S #103901
  CAS #50723-80-3
Sodium bisulfate  S #073201
  CAS #7681-38-1
Sodium fluoroacetate/1080
   S #075003
  CAS #62-74-8
Sodium hydroxide  S #075603
  CAS #1310-73-2
Sodium polysulfide  S #006902
  CAS #1344-08-7
Sodium TCA  S #081001
  CAS #650-51-1
S,S,Sr-tributyl phospho-
  rotrithioate (DBF)  S #074801
  CAS #78-48-8
Streptomycin  S #006306
  CAS #57-92-1
Strobane  S #020401
  CAS #8001-50-1
   Page

     44
13 & 43

     43

     43

      7

29 & 39

      7

     39

     26

      4


     26

     44

     44


     14

     44

      7
                                     Page

Strychnine/strychnine sulfate          22
  S # 076901, 02
  CAS #57-24-9
  CAS #60-41-3
Sulfur  S #077501                      35
  CAS #7704-34-9
Sulfuryl Fluoride  S #078003           26
  CAS #2699-79-8
Sulprofos (Bolstar®) S #111501         35
  CAS #35400-43-2
Tabutrex  S #077802                    45
  CAS #141-03-7
2,4,5-T/Silvex  S #082501          9 & 24
  CAS #93-765, 93-72-1
TCBC  S #017304                        39
  CAS 1344-32-7
TCC  S #027901                         26
  CAS #101-20-2
Tebuthiuron  S #105501                 29
  CAS #34014-18-1
Temephos (Abate®) S #059001            36
  CAS #3383-96-8
1081  S #075002                        14
  CAS #640-19-7
TEPP  S #079601                        37
  CAS #107-49-3
Terbacil  S #012701                    36
  CAS #5902-51-2
Terbufos  S #105001               36 & 37
  CAS #13071-79-9
Terbutryn  S #080813              14 & 42
  CAS #886-50-0
Terrazole®  S #084701                  36
  CAS #2592-15-9
Tetrachlorvinphos  S #083701           45
  CAS #961-11-5
Tetradifon  S #079202                  38
  CAS #116-29-09

-------
S 1102001
Tetrasul  S #079201
  CAS #2227-13-6
Thiophanate ethyl  S #103401
  CAS #23564-06-9
Thiophanate methyl
  CAS #23564-05-8
Thiram  S #079801
  CAS #137-26-8
Toxaphene S #080501
  CAS #8001-35-2
TPTH S #83601
  CAS #76-87-9
Treflan  S #036101
  CAS #1582-09-8
Triadimefon  S #109901
  CAS #43121-43-3
Triallate  S #078802
  CAS #2303-17-5
S,S,S-Tributyl Phosphoro-
   trithioate (DBF)  S #074801
  CAS #78-48-8
Tributyl phosphorotri-
  thioite (Merphos)  S #074901
  CAS #150-50-5
Trichlopyr  S #116001,2
  CAS #'s 55355-06-3;57213-69-l
Trichlorfon  S #057901         15,29
  CAS #52-68-6
2,4-5-Trichlorophenol  S #064204, 10
             11, 12, 14,
  CAS #95-95-4
Trifluralin  S #036101
  CAS #1582-09-8
Trysben (Benzac)  S #017303
  CAS #3426-62-8; 1338-32-5
Velpar®  see Hexazinone
Vendex  S #104601
  CAS #13356-08-6



23
29




14
Page
42
26
& 26
& 40
23
29
4i
40
& 42
     17, 19, 20
  14


  15

  45

S, 37

   4


  24

   7


  42
             Vernolate  S #041404
               CAS #1929-77-7
             Vitavax®  see Carboxin
             Warfarin  S #086002, 086003
               CAS #81-81-2
               sodium warfarin #129-06-6
               potassium warfarin #2610-86-8
             Zinc phosphide  S #088601
               CAS #1314-84-7
             Zineb  S #014506
               CAS #12122-67-7
             Ziram  S #034805,6
               CAS #137-30-4; 16509-79-8
Page

  39


  36



  36

  41

  44
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