JUNE 1983


                                     STATUS REPORT


                                          on


                 REBUTTABLE PRESUMPTION AGAINST REGISTRATION  (RPAR) OR
                                SPECIAL REVIEW PROCESS



                                REGISTRATION STANDARDS


                                          and


                               THE DATA CALL IN PROGRAMS
<*.;

O
    3
    O
OFFICE OF PESTICIDE PROGRAMS  (TS-767C)


U. S. ENVIRONMENTAL PROTECTION  AGENCY


        401 M. STREET,  S. W.


       WASHINGTON, D.C.  20460

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                            TABLE OF CONTENTS
RPAR' s Issued	 1

PRE-RPAR Revlew	6

Final Actions (Voluntary Cancellations)	 7

Notice of Intent to Cancel/Suspend	 9

Notice of Intent to Register (Returned to Registration Div.)	11

RPAR's Completed	17

Registration Standards Development - Data Collection	26

Registration Standards Development - Data Evaluation and
Development of Regulatory Position	28

Registration Standards Issued  	31

Data Call In	37

Index of Chemicals Included in Status report	46
                                                Prepared by
                                                Registration Support and
                                                Emergency Response Branch
                                                Registration Division
                                                (703) 557-7700

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                              REGISTRATION DIVISION
DIRECTOR

DEPUTY DIRECTOR

Insecticide-Rodenticide
     Branch

Fungicide-Herbicide
     Branch

Disinfectants Branch

Special Review Branch

Registration Support and
 Emergency Response Branch

DATA CALL IN PROGRAM (PM 51)

PM 12,  Jay Ellenberger

PM 15,  George LaRocca

PM 16,  William Miller

PM 17,  Timothy Gardner

PM 21,  Henry Jacoby

PM 23,  Richard Mountfort

PM 25,  Robert Taylor

PM 31,  John Lee

PM 32,  Arturo Castillo
Douglas D. Campt

Robert V. Brown

Herbert Harrison


James Akerman


Juanita Wills

Paul Lapsley

Ferial Bishop


Geraldine Werdig
(703)  557-7760

(703)  557-0592

(703)  557-2200


(703)  557-1650


(703)  557-3661

(703)  557-7420

(703)  557-7700
(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)

(703)
557-7436

557-2386

557-2400

557-2600

557-2690

557-1900

557-1830

557-1800

557-7163

557-7170

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                                       PREFACE

This publication contains: 1) an alphabetical listing of all chemicals which have been, or are
being, handled under the Rebuttable Presumption Against Registration [RPAR] process, (revisions
to the process and name change to Special Review are planned), 2) an alphabetical listing of the
chemicals which have been through or are now active in the Registration Standard development
process, and 3) identification by cluster of the chemicals which have been through or are being
processed in the Data Call-in program.  These processes are managed by the Registration Division;
Office of Pesticide Programs, Office of Pesticides and Toxic Substances, EPA.

This listing is intended for internal use and is updated setni-annually.  Users of this
document are encouraged to contact the appropriate PM or Branch Chief, as noted, if they have
any questions or corrections regarding the entries in this listing.

Sections of the law referred to in this document are from the Federal Insecticide,
Fungicide and Rodenticide Act (FIFRA) as amended 7 U.S.C. Section 136a(c)(2)(B).

All chemicals are listed by  the names under which they were or are being reviewed. Other widely
used common or chemical names may also appear in the Index.

Copies of most of the position documents (PD) and Registration Standards are available from the
National Technical Information Service (NTIS), U.S. Department of Commerce,  5285 Port Royal Road,
Springfield, Virginia, 22161 (703) 487-4600.  The accession number and costs for paper copy
and/or microfiche are cited  for those documents presently available from NTIS.

When requesting documents from the NTIS, state the name of the document, the NTIS
Accession Number, enclose proper payment (check payable to NTIS) and provide a return
mailing address.

                                      RPAR PROCESS *

Definitions of the risk criteria that, when met or exceeded, can trigger RPAR analyses,
can be  found  in the Federal  Register  of July  3, 1975 (40 CFR 162.11).  These risk criteria
are concerned with the following areas:

      1.  Acute Toxicity

      2.  Chronic Toxicity
          A.  Oncogenic
          B.  Mutagenic
 *  This process  is  undergoing  revision  via  rulemaking  and  a
   name change to  "Special  Review Process"  is  contemplated.

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 Other Chronic Effects
 A.   Reproductive
(1)   Fetotoxicity
(2)   Teratogenicity
     B.  Spermatogenicity
     C.  Testicular Effects
     D.  Neurotoxicity
     E.  Others

 Significant  reduction  in wildlife, reduction  in endangered species, and reduc-
 tion in nontarget species.

 Lack of emergency treatment  or  antidote.

                                 RPAR CATEGORIES

 The name  of  this process will be changed  from "RPAR"  to  "Special  Review" pursuant  to the new
 regulations  which are  planned for proposal  in the  near future.  That  is why  for  purposes of this
 report  the terms may be used interchangeably.  This  report is divided into a number of  categories
 to enable the reader to conveniently determine the current status of  a particular  pesticide.

   Pre-RPAR — This  is  the  initial risk  investigation  phase that involves an  intensive review of
 the scientific  studies of  the chemical  in question that  suggest that  the RPAR criteria  may have
 been exceeded.  A validation of these  studies of  the  chemical  in  question  is conducted  by Agency
 scientists.   During this period, the registrants  of  the  pesticide are informed of  the review and
 are often requested to submit additional  information. If  "trigger  studies"  are  found to be
 valid,  an effort  is made to  gather and  preliminarily assess  available information  on the exposure
 to the  pesticide.   If  such data are not available, the Agency  extrapolates from  models  or analogs
 and develops exposure  assumptions to hypothesize  the  potential  risk of the pesticide under
 review.   Major  "trigger studies" undergo  peer review (in accordance with Section 25e of FIFRA)
 to confirm the  EPA  validation.   Discussions are held  with  registrants and  other  interested
 parties in an attempt  to reduce exposure  to acceptable levels.   If  the risk  is reduced, or is
 found through review  to be acceptable,  the  RPAR review is  terminated.

 If risk is determined  to be  unacceptable, the validation of  the  "trigger studies"  and the
 combination  of  this hazard  information  with the exposure analysis produce  the Agency's
 preliminary  position  on the  potential  risk  of the pesticide.  The document describing this
 position  on  risk  is referred to as position document one (PD 1).  Upon approval  by the Agency, a
 notice of the availability of the PD  1  along with a  formal Notice of  Rebuttable  Presumption
 Against Registration  is published in  the  Federal  Register.
                                               11

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  Issuance of an RPAR--After a PD 1 is published, a 45 day period is allowed for comment
on tho presumptions against registration presented in PD 1.  A 60 day extension is granted,
if justified.  Therefore, there is typically a 105 day period within which the Agency's
pr<>sumptions may be rebutted.

Risks may be rebutted by interested parties submitting to the Agency: (1)  proof that the
study or studies upon which the presumption is based are not scientifically valid or (2)
proof that actual exposure to the compound will not cause the effects described. This phase
of the- process can be characterized as focusing on the gathering of additional information
in the form of:

             --rebuttal comments.
             --additional information on risk.
             --input from other agencies:  primarily the United States Department of
               Agriculture for information on benefits and exposure, and the United States
               Department of Interior, Office of Endangered Species for information on the
               implications of an environmental trigger.

in tho event that all the triggers have been successfully rebutted, the pesticide is re-
turned to the registration process and the RPAR is terminated for all or some of the uses.  The
results of this phase of the analysis is incorporated into a second position document (PD 2)
which states the Agency's regulatory action for the pesticide.  Any new information surfaced
during the rebuttal period is, of course, incorporated.  If the rebuttal is successful for all
or some of the uses, a PD 2 is published and becomes the final document of the RPAR process.

The Acjuncy only produces and publishes a separate PD 2 in those cases where the rebuttal
has boon successful.  When the rebuttal is not successful, the rebuttal assessment, the
risk analysis, the benefits analysis, risk/benefit synthesis and the proposed regulatory
position are presented in a document termed PD 2/3.

 A PD 2/3 is composed of the

    --introductory chapter which reviews the RPAR criteria which gave rise to the
      RPAR on the pesticide in question,
    --the risk analysis which reviews rebuttal comments, estimates exposure and caLculatos
      risks for the registered uses of the pesticide,
    --the benefit analysis which represents the impact of total cancellation of the
      pesticide in question,
    --the risk/benefit analysis of each of the regulatory options under considera-
      tion for resolution of the RPAR, and
    --the recommended regulatory position.
                                          111

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The full  range of  regulatory options  which  are  available  under  the law are examined.  These
range from full registration to  full  cancellation.   Between  the two ends of the regulatory
spectrum  are the options  that deal  with  labeling  changes, classification, and use restric-
tions.  The impact of  each  of these options on  the  benefits  and risk of each use of the
pesticide are considered.   The recommended  decision is  that  which presents the best balance
of risks  and benefits  in  the interest of public health  and the  environment.

At the conclusion  of the  risk/benefit evaluation, the completed PD 2/3 receives Agency review.
Discussions may be held with registrants and other  interested parties.  If the Assistant
Administrator for  the  Office of  Pesticides  and  Toxic Substances approves this document, a
notice of preliminary  determination and  an  announcement of the  document's availability are
published in the Federal  Register.

The FIFRA requires that the proposed  decision (PD 2/3)  be submitted to a Scientific
Advisory  Panel for review of its scientific basis and to  the Secretary of Agriculture for
comment.  These comments,  plus any industry  or public comments on the proposed decision, are
evaluated.  The Agency's  assessment of these comments,  including the final decision on the
regulatory action, are announced in the  Federal Register.  These are contained in publi-
cation PD 4 which  is also announced in the  Federal  Register.

     Activities After  Completion of RPAR's—This  document describes the status of those
chemicals that have, through a variety of means,  concluded their RPAR analyses.  This includes
chemicals which have been returned  to the registration  process, those which have been cancelled
or on which restrictions  have been  imposed, and those which  are currently in administrative
hearings, being reviewed  in court,  etc.


                                REGISTRATION STANDARDS

The Registration Standards  program  is EPA's approach to the  reassessment and reregistra-
tion of pesticide  products  as mandated by Congress  in FIFRA  Section 3 (g).  The reassessment
involves  a thorough review  of the scientific data base  underlying pesticide registrations and
an identification  of essential but  missing  scientific studies which may not have been required
when the  product was initially registered.   It  may  also require new testing or retesting to
ensure the safety  of the  compound by  contemporary scientific standards.

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The standards process involves making broad regulatory decisions at one time for a group
of pesticide products containing the same active ingredient rather than on a product-by-
product basis.  An estimated 600 standards will be developed representing most of the
35,000 currently registered pesticide products.  This approach to reregisration is
intended to simplify and streamline the regulatory process for both the Agency and pesti-
cide registrants and to assure the public that all registrations are supported by a
complete and valid scientific data base.

To establish the sequence of processing the approximate 600 active ingredients through the
Registration Standard review, active ingredients that have similar use(s) have been
clustered into 48 groups.  The groups are being processed in a sequence resulting from
their ranking in an equation based on production, human exposure, and ecological exposure
factors.  The ranking scheme was developed based on consideration of market competition,
availability of in-depth data on alternatives should the need for a Special Review arise,
and efficient use of EPA resources.

Each standard explains EPA's regulatory position on the use of the active ingredient in
all pesticide products containing that same chemical.  The standard contains an analysis
of the data on which the regulatory position is based, describes the rationale for the
regulatory position, and states the conditions that must be met to obtain pesticide
product registration.

The relationship of the Registration Standards process with the Special Review process
is that if the analysis of the data shows that a Special Review criterion has been met,
then the standard is issued announcing that a Special Review will be initiated for some or
all of the uses of the chemical.  When the Special Review process is completed, the result
of the Special Review will then be incorporated into the standard.

Registration Standards are developed in three phases:  1) Data Gathering, 2) Data
Evaluation, and 3) Regulatory Position Development followed by the issuance of the
Registration Standard Guidance Package.  For convenience, phases 2 and 3 are combined
in this report and the issued documents are identified separately in the attached listing.

1)  Data Gathering: The bibliography is sent to the major registrants for comment.  The
bibliography consists of all data in Agency files pertaining to the chemical, except that
in most cases efficacy data are not listed.  The bibliography will also include any
government studies (such as NCI studies) which have been conducted on the chemical and
other relevant material identified by Agency scientists.

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Registrants are asked to comment on the completeness of the entire list and whether
there are duplicates listed.   Registrants are asked to submit additional studies which
may never have been submitted to the Agency previously but which they consider to be
relevant to the review.

Once the bibliography has been commented on by the registrants, reviewed by Agency scien-
tists, and Agency scientists  have identified which studies should be reviewed, hard copy
of all requested studies are  retrieved from Agency files and provided to Agency scientists
for review.  The data gathering phase lasts about five months.

Once the data gathering phase is completed, and the use information is developed (usually
jointly by registrants and Agency use experts), the data evaluation phase is ready to
begin.

2} Data Evaluation; At the outset of the Data Evaluation phase, the Project Support Team,
which consists of all Agency  staff involved in the Registration Standard review (Regis-
tration/reregistration Product Manager, use experts, data retrieval experts, and Agency
scientists) meet to exchange  information regarding the chemical from a regulatory and
scientific perspective.  Following this meeting, registrants are invited to attend a
subsequent meeting to provide an overview from their perspective.  These two meetings are
designed to provide a context in which the scientists conduct their review.  Knowledge of
the regulatory history, the growth patterns of the chemical's use, general understanding
of the completeness of the data base, and discussion of any past regulatory/health
problems will help focus the  review and increase the scientists' effectiveness.

With this perspective, scientists review data in each of five disciplines: product
chemistry, environmental fate, residue chemistry, toxicology, and ecological effects.
Efficacy data are reviewed only for products which control infectious microorganisms and
the growth of aflatoxins.  The scientists document their review of each study which they
consider relevant, and prepare a summary of what is known about the chemical in their
respective discipline.  Scientists also identify gaps in the data base which should be
filled to enable a complete scientific assessment to be made.  While the 40 CFR Part 158
guidelines*  (currently proposed) are used as guidance to make the determination of data
gaps, each chemical is reviewed individually to determine, given its particular use
patterns and what is already  known about it, what additional data are needed.  If the
resulting data needs differ from those in the Guidelines, the scientist provides written
justification for the deviation.  Depending on the size of the data base involved in the
review, this phase usually lasts from six to ten months.
 *See p.viii  for specific citation.

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3J Development of Regulatory Position and  Issuance of Guidance Package:  Once the
Science review is completed and scientists have  recommended which additional
data they believe are necessary to complete the  review,  the project Support Team
reconvenes to identify the appropriate regulatory position for the chemical (that
is, what percent active ingredient, formulations, uses,  etc. are registerable under
the Standard and whether regulatory restrictions such as label warnings  or use by
certified applicators only are required).   They  also develop the rationale for the
regulatory position and determine the data requirements  which need to be imposed to
complete the review.  Included in this phase is  the tolerance reassessment which
may result in the initiation of rulemaking to increase or decrease tolerance levels.

Once the proposed regulatory position/rationale  and data requirements are drafted,
they are provided to the registrant for comment.  The registrants may choose to
modify his manufacturing process or use patterns to eliminate the need for additional
label warnings, may provide further information  which affects the exposure profile,
or provide many other observations or information which could affect the final
statement.  Once the registrant comments are received, the proposed regulatory
position and rationale, data requirements, scientific summaries
circulated to Agency management for review.
                                                                 and bibliography are
After the document is approved,  study reviews and science summaries are placed in
Agency records for retrieval  during subsequent reviews of the chemical (e.g.
registration amendments)  as their availability is expected to expedite the processing
of future reviews.  Copies of the study reviews and the science summaries are
available through OPP's Freedom  of Information Section.  The regulatory position/
rationale, data requirements, and bibliography are sent to the registrant in a
document known as a Guidance  Package which cites the authority of Section 3(c)(2)(B)
and Section 3 (g) of FIFRA.  Reregistration occurs when the registrant agrees to
comply with the data requirements, submits an updated Confidential Statement of
Formula if needed, agrees to  comply with any regulatory restrictions placed on the
chemical, agrees to compensate other registrants for data considered relevant to the
Standard, and provides labelling reflecting completion of any product chemistry and
acute toxicity data requirements.
                                               VII

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issuance of  the Standard;    The standard  is  issued to the registrants and made  available
to the public through the National Technical  Information  Service, 5285 Port  Royal  Road,
Springfield, VA 22152 telephone 703-487-4650.  Microfilm  copies are available  for  $4.50;
the price of paper copies varies according to the length  of  the document.  please  furnish
NTIS with the accession number or the PB number when ordering.


                             THE DATA CALL IN PROGRAM

The Data Call In  Program requires existing registrants of active pesticide chemicals  to
provide the  Agency with needed long-term chronic toxicological studies under Section
 (c)(2)(B) of FIFRA.  Such studies are an integral part of the data base used to  reassess
each chemical during the reregistration process.  This reassessment is the forerunner of
the development of the Registration Standard/Guidance Package, described previously.

The purpose  of Data Call In  is to assure that data from needed long-term testing  (2-4
years)  are available or well underway before  the pesticide chemical is reassessed  for
reregistration under Section 3(g).  These  long-term chronic  studies provide  essential
chronic health effects data  needed to determine that a pesticide performs  its  intended
function without  causing unreasonable adverse effects on  the environment (Section  3(c){5})
The program  is being accelerated so that studies will be  requested at least  2  to 4 years
before  the data base is reassessed for reregistration.

The  four types of long-term  toxicological  data which are  requested consist of  (Zhronic
Feeding, Oncogenicity, Reproduction and Teratogenicity  (informally referred  to as  the
CORT studTes).  These studies are described  in the Toxicology Data Requirements  part
of  the  "pesticide Registration: Proposed Data Requirements"  regulation.*

 Under  the  Data Call In Program, the Agency 1) determines  which of the four types of
chronic test data are required for each chemical, based on its use patterns  and  other
 factors; 2)  identifies those test categories  with no valid data submitted; and 3)
 ensures that studies are initiated by registrants of the  pesticide product to  fill
 those  data gaps.   Registrant assistance is requested for  the confirmation  of data  gaps.

 The  sequence of processing the approximate 600 active ingredients through  the  Data Call
 In  process  is  based on the priority cluster  ranking  in which active ingredients  that
 have a similar use(s) are clustered into about 50 groups  and the groups are  processed
 in  sequence.  A notice of the availability of the final cluster ranking was  published


*The Pesticide  Registration Guidelines were
 reproposed  as  Part 158,40 CFR on November  24,
   82 in 47  Federal Register  53192.       	
           —		                      ^^^^^^^^B    . ,
                                               Vlll

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in the Federal Register, 47 FR 3770,  January 24,  1982.   Chemicals now being processed into
Registration Standards or which are in the RPAR process are deferred from the Data
Call in program.

In each Notice, the registrant can request the Agency to waive any or all of the specified
data requirements.  Registrants may request changes or waivers of the data requirements
because:

    1.  They believe the data requirements are inappropriate for their chemical.
    2.  They determine that their chemical involves only minor exposure and production.
        In addition, registrants may cite economic factors as precluding its capacity to
        incur the costs of testing.
    3.  They need a longer time period to complete the testing.
    4.  They wish to remove all registered uses which involve food crops/products and/or
        significant repeated exposure to humans and the environment.
    5.  They wish to use a protocol that differs  from EPA or OECD guidelines.

If the Agency does not grant the change(s) or waiver(s), the registrants must arrange to
comply with the Notice.

If a registrant does not respond or comply with the Data Call in Notice, the Agency will
issue an Administrative- Notice (NOIS—Notice Of Intent to £3uspend) compelling the regis-
trant to stop distributing the particular pesticTde product(s) until compliance with the
Notice occurs.  The actual effect of a NOISe is to put a registration "on hold" until such
time as the registrant wishes to make his registration active.  Any such NOISe issued under
Section 3(c)(2)(B) is rescinded when the Agency is informed and agrees that compliance
occurs.  Such Noises never, independently, result in cancellations and are therefore clear-
ly different from the FIFRA Section 6 suspensions which can later become cancellations
and cause the withdrawal of pesticide products from the market.

This report gives the status of all chemicals and clusters being processed through Data
Call In.  The status includes whether a Notice or equivalent has been issued and whether
the Agency has reached a final decision on all the waivers, exemptions, cancellations,
commitments and offers received from registrants.
                                          IX

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                                         RPARs ISSUED
                                                       June 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
CADMIUM
(Special Review Br,
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Fetotoxicity
  PD 1 published, 42 FR 56574
  (10/26/77); comment period
  closed 2/10/78.
  Risk/benefit assessment may be
  conducted in FY-84.
CAPTAN
(Special Review Br.)
CARBON TETRACHLORIDE
(Special Review Br.)
COAL TAR
(Special Review Br.)
o  Oncogenicity
o  Mutagenicity
o  Other Chronic Effects
o  Oncogenicity
o  Toxic effects on
   liver and kidney
o  Oncogenicity
o  Mutagenicity
o  PD 1 published, 45 FR 54938
   (8/18/80); comment period closed
   12/1/80: NTIS# PBS 1 109449.
o  Risk/benefit assessment is ongoing.

o  PD 1 published, 45 FR 68534
   (10/15/80); comment period
   closed 11/24/80: NTISf PB80 121782.
o  Risk/benefit assessment is ongoing.
o  PD 1 published, 43 FR 4815.4
   (10/18/78); comment period" closed
   9/30/78: NTIS# PB80 213879
o  PD 2/3 (wood uses only) completed
   and Notice of Determination pub-
   lished in 46 FR 13020 (2/19/81);
   comment period closed 5/20/81;Report
   # 540/9-82-004; NTIS f PB 82-229956
o  At 4/14/83 public meeting, proposed
   conclusion presented. Comment period
   closed 5/13/83.
o  Final decision is being developed.

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                                  RPAR's ISSUED -  Cont'd
                                                               June 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
    CURRENT
    STATUS
CREOSOTE
(Special Review Br.)
EPN
Ethyl p-nitro-
phenyl thionoben-
zenephosphonate
(PM-12)
ETHYLENE DIBROMIDE
  EDB
 (Spcial Review Br. )
ETHYLENE OXIDE
EtO
(Special Review Br.)
    o Oncogenicity
    o Mutagenicity
    o Neurotoxicity
    o Oncogenicity
    o Mutagenicity
    o Reproductive Effects
    o Oncogenicity
    o Mutagenicity
    o Testicular Effects
o Same as above (Coal Tar/Creosote
  Coal Tar Neutral Oil PD 1 and
  PD 2/3 combined).  NTIS#82-229956
o PD 2/3 (wood uses only) completed
  and Notice of Determination pub-
  lished in 46 FR 13020  (2/19/81);
  comment period closed  5/20/81. Report
  tt 540/9-82-004 NTIS #  PB 82-229956
o At 4/14/83 public meeting proposed
  conclusion presented.  Comment period
  closed 5/13/83.
o Final decision is being developed.

o PD 1 published, 44 FR  54384
  (9/19/79); comment period closed
  12/29/79:  NTISt PB80  216815
o Final Notice of Determination and
  Decision Document forwarded to
  Acting AA on June 30,1983.

o PD 1 published, 42 FR  63134
  (12/14/77); comment period closed
  4/3/78:  NTIS# PB80 109456.
o PD 2/3 completed and Notice of
  Determination published, 45 FR
  81586 (12/10/81);  comment period
  closed 3/9/81.
o PD 4 being revised

o PD 1 published, 43 FR  3801
  (1/27/78); comment period closed
  5/15/78:  NTIS# PB80 213903
o Label improvement hospital use.
o Regulatory position document fo.
  hospital use being developmen

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                                      RPARs ISSUED - Cont'd
                                                           June 1983
CHEMICAL {Class Of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
                            CURRENT
                            STATUS
INORGANIC
ARSENICALS
  Arsenic Acid,
  Arsenic Pentoxide,
  Arsenic Trioxide,
  Sodium Arsenate,
  Ammonium Arsenite,
  Sodium,
  Pyroarsenate,
  Lead Arsenate
  Basic and Standard)
  Calcium Arsenate,
  Sodium Arsenite,
  Copper Acetoarsenite
  (Special Review Br.)

LINDANE
 {Special Review Br.)
o
o
o
o
o
o
o
o
Oncogenicity
Mutagenicity
Teratogenicity
Oncogenicity
Teratogenicity
Reproductive Effects
Acute Toxicity
Other Chronic Effects
PD 1 published, 43 FR 42867.
(10/18/78); comment period closed
2/12/79.
PD 2/3 (wood uses only) completed
and Notice of Determination pub-
lished in 46 FR 13020 (2/19/81);
comment period closed 5/20/81;
At 4/14/83 public meeting proposed
conclusion presented. Comment
period closed 5/15/83.
Final decision being developed.
PD 1 published, 42 FR 9816
(2/18/77); comment period closed
6/20/77:  NTIS# PB80 213911
PD 2/3 completed and Notice of
Determination published, 45 FR
45362 (7/3/80); comment period
closed 9/15/80.
PD 4 being developed.

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                                    RPAR'S ISSUED - Cont'd
                                                          June 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11  CRITERIA
POSSIBLY MET OR EXCEEDED
STATUS
PENTACHLOROPHENOL
AND DERIVATIVES
(Special Review Br.)
SODIUM FLUORO-
ACETATE/1080
(Special Review Br.)
STRYCHNINE/
STRYCHNINE
SULFATE
(Special Review Br.)
o  Oncogenicity
o  Fetotoxicity
o  Teratogenicity
   Reduction in Non-target
   and Endangered Species
   No antidote
o  Reduction in Non-target
   and Endangered Species
   PD 1 published, 43 FR 48443
   (10/18/78); comment period closed
   2/12/79:  NTIS# PB81 109464.
   PD 2/3  (wood used only) completed
   and Notice of Determination pub-
   lished in 46 FR 13020 (2/19/81)?
   comment period closed 5/20/81;
   At 4/14/83 public meeting proposed
   conclusion presented. Comment
   period closed 5/13/83.
   Final decision being developed.

   PD 1 published, 41 FR 52792
   (12/1/76); comment period closed
   3/15/77:  NTIS# PB80 216823
   PD 2/3 signed on 11/11/82.
   Release delayed to coincide
   with that of document addressing
   predator issues in early 1983.
   PD 2/3 resigned by Acting AA on
   6/29/83.

   PD 1 published, 42 FR 2713
   (1/13/77); comment period closed
   3/15/77:  NTIS# PB80 216807
   PD 2/3 completed and Notice of
   Determination published, 45 FR
   73602 (11/5/80); comment period
   closed  9/30/81:  NTIS# PB81 123960
   PD 4 being developed.

-------
                                      RPARs ISSUED - Cont'd
                                                          June 1983
CHEMICAL (Class of
Chemicals)  and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
2,4-5-TRICHLORO-
PHENOL
(Special Review Br,
o  Oncogenicity
o  Fetotoxicity
                                                      o
   PD 1 published, 42 FR 41268
   (9/15/78); comment period closed
   11/17/78.
   Possibility of TCDD contamination
   under investigation.
   3(c)(2)(B) letters issued requesting
   additional data from registrants.
   Some voluntary cancellations and
   reformulations being processed.
   Further review pending completion of
   2,4,5-T hearings.

-------
                                   PRE-RPAR REVIEW
                                          June 1983
CHEMICAL (Class of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
                            CURRENT
                            STATUS
RONNEL
  0 ,0-dimethyl
  0-(2,4,5-trichlo-
  rophenyl) phosphoro-
  thioate (related to
  2,4,5-T)
  (Special Review Br.)
o
o
o
Oncogenicity
Teratogenicity
Fetotoxicity
No action pending 2,4,5-T
hearing settlement.

-------
CHEMICAL
(Class of Chemicals)
                                      FINAL ACTIONS
                           VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS
                                             June 1983
40 CFR 162.11 CRITERIA     DATE OF FEDERAL
POSSIBLY MET OR EXCEEDED   REGISTER PUBLICATION
ACRYLONITRILE
  (three products)


ARSENIC TRIOXIDE
o  Oncogenicity
o  Teratogenicity
o  Neurotoxicity

o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
BENZENE                    o  Oncogenicity
  (all except one product) o  Mutagenicity and
                              Blood Disorders
BHC
CHLORANIL

CHLORDECONE
  Kepone
  (Products of six
  formulators)

COPPER ACETOARSENITE
o  Oncogenicity


o  Oncogenicity

o  Oncogenicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  43 FR 26310 (6/19/78).
o  42 FR 45944 (9/13/77).
                           o  Voluntary cancellations
                              completed.
o  43 FR 31432 (7/21/78)
   NTIS# PB80 216781

o  42 FR 3702 (1/19/77),

o  42 FR 38205 (7/27/77)
   NTIS# PB80 216773
o  42 FR 18422 (4/7/77).
BASIC COPPER ARSENATE
  (all products)

ERBON
o  Oncogenicity
o  Oncogenicity
o  Teratogenicity
o  Fetotoxicity
o  42 FR 18422  (4/7/77).
O  45 FR 58770  (10/4/80)

-------
                                        FINAL ACTIONS
                      VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS - CONT'D
                                               June 1983
CHEMICAL
{Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ISOCYANURATES
  (some products)
MONURON
  (some products)

OMPA
  Octamethylpyro-
  phosphoramide

PERTH AN E
  (many products)

PHENARSAZINE CHLORIDE

SAFROLE
SODIUM ARSENITE
   (two products)
STROBANE

TRYSBEN
o  Kidney effects
o  Oncogenicity
o  Oncogenicity
o  Oncogenicity
o  None

o  Oncogenicity
o  Mutagenicity
o  Oncogenicity
o  MutagenjLcity
o  Teratogenicity

o  Oncogenicity

o  Oncogenicity
o  Voluntary cancellations
   being processed.
o  Registrants have either
   undertaken or scheduled
   numerous toxicological
   studies.

o  42 FR 41320 (8/16/77).
O  41 FR 21859 (5/28/76).
o  45 FR 41694 (6/20/80).
O  42 FR 59776 (11/21/77)

o  42 FR 11039 (2/25/77).
o  42 FR 16844 (3/30/77).
o  42 FR 29957 (6/10/77).

o  43 FR 48267 (10/18/78)
o  41 FR 26607 (6/28/76).

o  43 FR 5782  (2/9/78).

-------
                         NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED
                                                  June 1983
CHEMICAL
(Class of Chemicals)
40 CPR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ALDRIN/DIELDRIN
CHLORDANE/HEPTACHLOR
CHLORDECONE
  Kepone
DBCP
ODD (TDE)
DDT
DINITRAMINE
ENDRIN
o  Oncogenicity
o  Reductions in Non-target
   and endangered species

o  Oncogenicity
o  Oncogenicity
o  Mutagenicity
o  Reproductive Effects
o  Oncogenicity
o  Oncogenicity
o  Teratogenicity
o  Reduction in En-
   dangered Species
   and Non-target
   Species
o  39 FR 37216 (10/18/74);
   (Cancellation of most uses),

o  Notice of Intent to Cancel
   39 FR 41298 (11/26/74).
   (Cancellation of most uses).

o  PD 1 published, 41 FR 12333
   (3/25/76).
o  PD 4 published, 42 FR 18885
   (4/11/77).
o  Notice of Intent to Cancel
   42 FR 18885 (4/11/77).

o  See listing under "RPAR's
   COMPLETED".
o  36 FR 5254 (3/18/71);
   (Cancelled).

O  37 FR 13369  (7/7/72);
   (Cancellation of most uses)

o  Notice of  Intent to Suspend
   under Sec. 3(c)(2)(B)
   issued on  9/28/82.

o  See listing  under  "RPAR's
   COMPLETED".

-------
                      NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED Cont'd
                                                     June 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
MIREX
2,4,5-T/SILVEX
o  Oncogenicity
o  Teratogenicity
o  Fetotoxicity
                                                      o
   41 FR 56703 (12/29/76)?
   {Most uses cancelled).

   PD 1 published, 43 FR 17116
   (4/21/78):  2,4,5-T - NTIS#
   PB80 212665
   Emergency Suspension Order and
   Notice of intent to Cancel pub-
   lished, 44 FR 15874 (3/15/79):
   2,4,5-T -  NTIS# PB80 225923
   Silvex -  NTIS# PB80 226376
   PD 4 published, 44 FR 72316
   (12/13/79).
   Cancellation Hearings began
   3/14/80. The Agency is nego.
   w/ involved parties to resolve
   the hearing.
                                                 10

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                             NOTICE OF INTENT TO REGISTER ISSUED
                            ( Re tu r ned to the Reg i s trat ion Proce s's)
                                                                        June 1983
CHEMICAL
(Class of
Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
CACODYLIC ACID
AND SALTS
  (PM-23)
CARBARYL
 (PM-12)
               o  Oncogenicity
               o  Mutagenicity
               o  Teratogenicity
               o  Oncogenicity
               o  Mutagenicity
               o  Teratogenicity
                                Insufficient evidence to issue a
                                RPAR.
                                Decision document published in
                                Federal Register, 47 FR 20376,
                                (5/12/82).  Returned to the
                                Registration process in Dec. 1981
                                with the stipulation that pursuant
                                to FIFRA Section 3(c)(2)(B), data
                                on the rate of dermal absorption be
                                submitted, knapsack/hand sprayer
                                applicators treating ditch banks
                                and rights-of-way will wear
                                respirators or masks, and labels
                                recommend masks for homeusers
                                employing knapsacks or hand
                                sprayers.

                                45 FR 81869 (12/12/80). The Agency
                                has returned this compound to the
                                registration process with the stipu-
                                lation that the following measures
                                be considered:  1) a FIFRA Section
                                3(c)(2)(B) action that registrants
                                remedy data limitations identified
                                in pre-RPAR review and, 2) appro-
                                priate label changes be made to
                                minimize exposure to carbaryl.
                                Both measures are being considered
                                in the Reregistration review of
                                this chemical.
                                         11

-------
                               NOTICE OF INTENT TO REGISTER ISSUED
                              (Returned to theRegistration Process)
                                                         June 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
 DATE OF FEDERAL
REGISTER PUBLICATION
CHLOROFORM
  Trichloro-
  methane
  (PM-16)
DICHLORVOS
  DDVP
  2 ,2-dichlorovinyl
  dimethyl phosphate
  (PM-15)
DIFLUBENZURON
  Dimilin
   (PM-17)
o  Oncogenicity
o  Oncogenicity
   Mutagenicity
o  Reproductive Effects
o  Fetotoxicity
o  Neurotoxicity
o  Oncogenicity
o  Hazard to Wildlife and
   other Chronic Effects
   PD 1 published, 41 FR 14588
   (4/6/76); comment period closed
   7/23/76.
   FR Notice announcing termination
   of this RPAR issued in December,
   1982. The agency determined that
   applicator exposure had been
   reduced to a minimum as a result
   of label amendments. Also regis-
   trants were required to submit
   data to establish tolerances of
   permissible residues on raw
   agricultural commodities.

   47 FR 45075 (10/13/82).
   NTIS no. not available.
   Returned to the Registration
   Process September 29, 1982
   stating that the Agency will
   reassess carcinogenic potential
   and the need for additional
   Oncogenicity data upon comple-
   tion of an in progress NCI bio-
   assay.  Additional tests on
   mutagenicity were required.

   RPAR action completed in April 1979
   Registrant consented to restricted
   uses.

-------
                                NOTICE OF INTENT TO REGISTER ISSUED
                               (Returned to the Registration Process)
                                                          June 1983
CHEMICAL
(Class of Chemicals)

MALEIC HYDRAZIDE
  MH
 (PM-25)
  •}(s  :t'P 162.11 CRITERIA
  POSSIBLY MET OR EXCEEDED
                             DATE OF FEDERAL
                             REGISTER PUBLICATION
  o
   Oncogenicity
o  Mutagenicity
o  Reproductive
                  Effects
METHANEARSONATES
  includes Amine
  Methanearsonate,
  Calcium Acid Meth-
  anearsonate, Mono-
  ammonium Methane-
  arsonate (MAMA),
  Monosodium Methane-
  arsonate (MSMA),
  Disodium Methane-
  arsonate (DSMA)
  (Special Review Br.)

NALED
  (PM-16)
o  Oncogenicity
o  Mutagenicity
o  Mutagenicity
o  Fetotoxicity
o  Reproductive Effects
PD 1 published, 42 FR 56920
(10/28/77), comment period closed
12/14/77:  NTIS# PB80 216740
Decision document returning maleic
hydrazide and salts (K-MH, DEA-MH}
to registration process signed 6/28/82.
Report #540/9-82-010; NTISI PB 82240300
FR Notice has been combined with
chloroform (see chloroform entry).
Additional reproductive and muta-
genicity studies have been per-
formed on K-MH as required.
Registrants decided not to per-
form similar tests on DEA-MH and
thus DEA-MH was suspended 11/81.

On 6/28/83 the pre-RPAR review for
methanearsonate chemicals was
completed and a decision memo was
approved returning these chemicals
to the normal registration process.
The existing evidence was inadequate
to initiate an RPAR for the chemicals.
However,additional data will be
required through a 3(c)(2)(B) notice
to determine if there are any risk
concerns.
                                 Chemical  returned  to  normal  registra-
                                 tion process  on  6/30/83.  Based  on a  re-
                                 view of all available data,  no  valid
                                 tests  or  definitive evidence exist which
                                 meet or exceed the RPAR  risk criteria.
                                 However,  additional tests have  been  re-
                                 quired and will  be reviewed  to  determine
                                 whether there are  any risks  of  concern.
                                                   13

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                                NOTICE OF INTENT TO REGISTER ISSUED
                               {Returned to the Registration Process)
                                                          June 1983
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
                          DATE OF FEDERAL
                          REGISTER PUBLICATION
10,10'Oxybisphen-
  oxarsine
  (Some uses)
   (PM-22)
PARAQUAT
 (PM-25)
o  (Arsenical Compound)
   suspected:
   - Oncogenicity
   - Mutagenicity
   - Teratogenicity

o  Emergency Treatment
o  Chronic Effects
PIPERONYL BUTOXIDE
  (PM-17)
o
o
ROTENONE
 (PM-17)
O
o
o
o
o
o
Co-Carcinogenicity
Carcinogenicity
Oncogenicity
Mutagenicity
Teratogenicity
Reproductive Effects
Chronic Toxicity
Significant Wildlife
Populations Reductions
Acute Toxicity to
Aquatic Wildlife
                          o  Returned to the Registration
                             Process on April 9, 1979 based
                             on Memo indicating no evidence
                             of Oncogenicity.
o  Decision document returning
   paraquat to the Registration
   Process was signed on 6/29/82.
   FR Notice 47 FR 45075, pub-
   lished October 13, 1982. NTIS
   no. not available.  Decision
   Document outlines data gaps and
   voluntary cancellation of certain
   noncrop use sites.

o  Decision document complete.
o  FR Notice 47 FR 20376 pub-
   lished 5/12/82.  NTIS #PB 83-137901.
   Returned to the Registration
   Process on May 12, 1982.
   Section 3(c)(2)(B) notice .
   requesting additional data
   issued on Sept. 30, 1982.

o  Notice of Availability of De-
   cision document published,
   46 FR 36745 (July 15, 1981). NTIS
   no. not available. Returned to
   Registration Process based on
   finding no unreasonable adverse
   effects.
                                                     14

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                               NOTICE OF INTENT TO REGISTER ISSUED
                              (Returned to the Registration Process)
                                                        June 1983
CHEMICAL
(Class of Chemicals)
 40 CFR 162.11 CRITERIA
 POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
1081
(PM-16)
   Acute Toxicity to Mam-
   malian and Avian Species
   Reduction in endangered
   and non target species
   Acute Toxicity without
   antidote.
   PD 1 published, 41 FR 52792
   (12/1/76):  NTIS# PB80 216823
   PD 2 published  45 FR 13189.
   (2/28/80): NTIS# PB80 216831.
   Returned to Registration Pro-
   cess with the restriction
   that it be used only in sewers
TERBUTRYN
(PM-25)
o  Oncogenicity
o  Mutagenicity
o  Reproductive Effects
S,S,S-TRIBUTYL
PHOSPHOROTRITHIOATE
(DEF)
(PM-25)
o  Neurotoxicity
TRIALLATE
(PM-25)
o  Oncogenicity
o  Mutagenicity
o  PRE-RPAR evaluation completed.
o  Returned to the Registration
   Process. Registrants agreed
   to change label to reduce
   applicator risk to acceptable
   levels. 47 FR 20376, published
   5/12/82. NTIS no. not available.

o  PRE-RPAR evaluation completed.
o  Returned to Registration Divison,
   11/30/81, based on finding of no
   potential unreasonable adverse
   effects. Registrants agreed to
   practice clothing requirement.
   47 FR 20376, published 5/12/82.
   NTIS no. not available.

o  45 FR 82349 (12/15/80). The
   Agency determined that, in light
   of the low level of exposure, it
   should be returned to the regis-
   tration process stipulating that
   a FIFRA 3(c)(2)(B) action be
   initiated to obtain necessary
   toxicity data to evaluate its
   hazards.
                                             15

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                             NOTICE OF INTENT TO REGISTER ISSUED
                            (Returned to the Registration Process)
                                                      June 1983
CHEMICAL
(Class of Chemicals)
40C CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
TRIBUTYL PHOSPHORO-
TRITHIOITE
(Merphos)
(PM-25)
TRICHLORFON
(PM-16)
o  Neurotoxicity
o  Oncogenicity
o  Mutagenicity
o  Teratogenicity
o  Fetotoxicity
o  Reproductive Effects
o  PRE-RPAR evaluation completed.
o  Returned to Registration Divi-
   sion, 11/30/81, based on finding
   no potential unreasonable adverse
   effects. Registrants agreed to
   protective clothing requirement.
   47 FR 20376 published 5/12/82.
   NTIS no. not available.

o  Removed from Pre-RPAR review as
   it chemically relates to dichlorvos.
   See dichlorvos.

-------
                                      RPARs COMPLETED
                                                        June 1983
CHEMICAL (Class of
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
AMITRAZ
  Baam
(PM-12)
o  Oncogenicity
   PD 1 published, 42 FR 18299
   (4/6/77); comment period closed
   7/18/77: NTISf PB80 212046
   PD 2/3 completed and Notice of
   Determination published, 44 FR
   2678 (1/12/79); comment period
   closed 2/12/79: NTIS# PB80 211436
   PD 4 published, 44 FR 32736
   (6/7/79); 44 FR 59938 (10/7/79}
   (correction):  NTIS# PB80 211428
   - conditional registration
     approved for pears but
     not for apples.
   - registrants will conduct
     an oncogenicity study and
     collect additional benefits
     data.
   - tolerance for pears approved
     12/6/79.
                                         17

-------
                                     RPARs COMPLETED cont'd
                                                      June 1983
CHEWICAL (Class of
Chtwicals) and
Ri^ONSIBLE
     BRANCH
40 CFR 162.11 CRITEEIA
POSSIBLY MET O* E*CB«|KD
CURRENT
STATUS
BENOMYL
(PM-22)
o  Reduction in non-target
   species (rebutted)
o  Mutagenicity
o  Teratogenicity
o  Reproductive Effects
o  Hazard to Wildlife
   PD 1 published, 42 FR 61788
   (12/6/77).
   PD 2/3 completed and Notice of
   Determination published, 44 FR
   51166 (8/30/79); comment period
   closed 9/28/79.
   PD 4 completed and Notice of .
   Determination published, 47 FR 46747
   (10/20/82).  NTIS# PB 83-148189.
   The Notice requires use of either
   cloth or commercially available
   disposable dust masks by mixer/loaders
   of benomyl intended for aerial
   application and that registrants of
   benomyl products conduct field
   monitoring studies to identify
   residues that may enter aquatic sites
   after use on rice.
                                                  18

-------
                                        RPARS COMPLETED - Cont'd
                                                          June 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
                           CURRENT
                           STATUS
CHLOROBENZILATE
(PM-12)
o
o
Oncogenicity
Testicular Effects
DBCP
  1, 2-dibromo-
  3-chloropropane
  (PM-21)
o
o
Oncogenicity
Reproductive Effects
PD 1 published, 41 FR 21517
(5/26/76); comment period closed
7/28/76.
PD 2/3  and Notice of Proposed Deter-
mination published, 43 FR 29824
(7/11/78); comment period closed
8/10/78:  NTIS# PB80 213887
Final Determination based on PD 2/3
published, 43 FR 29824 (7/11/78).
PD 4 and Notice of Intent to Cancel
published, 44 FR 9547 (2/13/79):
NTIS# PB80 213929

PD 1 published, 42 FR 48026
(9/22/77); comment period closed
11/7/77.
Suspension Order and Notice of Intent
to Cancel published, 42 FR 57543
(11/3/77).
Amended Notice of Intent to Cancel
and PD 2/3/4/ published, 43 FR 40911
(9/13/78):  NTIS # PB80 213853
Notice of Intent to Suspend all pro-
ducts issued, 44 FR 41783 (7/18/79).
Suspension Order (affecting all uses
except pineapple) and Notice of Intent
to Cancel all Uses published, 44 FR
65135 (10/29/79).
Agreement reached with registrants
that all uses, except on pineapples
are cancelled.
                                              19

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                                      RPARS COMPLETED - Cont'd
                                                           June 1983
CHEMICAL (Class Of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
DIALLATE
  (PM-25)
DIMETHOATE
  (PM-16)
o  Oncogenicity
o  Mutagenicity
o  Oncogenicity
o  Mutagenicity
o  Fetotoxicity
o  Reproductive effects
   PD 1 published, 42 FR 27669
   (5/31/77); comment period closed .
   9/9/77:  NTIS# PB80 212863
   PD 2/3 completed and Notice of
   Determination published, 45 FR
   38437  (6/9/80)j comment period
   closed 7/9/80:  NTIS# PB80 216849:
   PD 4 completed and announced in
   Federal Register, 47 FR 27109
   (6/23/82).  NTIS no. not available

   Classifies current products for
   restricted use by certified
   applicators wearing protective
   clothing.

   PD 1 published, 42 FR 45806
   (9/22/77); comment period closed
   1/6/78.
   PD 2/3 completed and Notice of
   Determination published, 44 FR
   66558  (11/19/79); comment period
   closed 12/19/79:  NTIS* PB80
   213846
   PD 4 published, 46 FR 5334
   (1/19/81). NTIS no. not available.
   Registration Standard approved and
   signed 3/31/83.

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                                    RPARs COMPLETED - Cont'd
                                                       June 1983
CHEMICAL (Class of
Chemicals)  and
RESPONSIBLE
SPED BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
                             CURRENT
                             STATUS
EBDC's
  Ethylenebis-
  dithiocarbam-
  ates, maneb,
  mancozeb,
  metiram, nabam,
  zineb, amobara
  (PM-21)
o
o
o
Oncogenicity
Teratogenicity
Hazard to Wildlife
 ENDRIN
  (PM-15)
o
o
Oncogenicity
Teratogenicity
Reduction in en-
dangered species and
nontarget species
o  PD 1 published,_42 FR 40618
   (8/10/77); comment period closed
   12/23/77.
o  Decision Document and Final
   Determination published, 47 FR
   47669 (10/27/82). NT1S no. not
   available.  The Notice returned
   EBDC products to the Registration
   Process on condition that certain
   use precautions are added to the
   product labels and registrants
   agree to generate additional
   toxicology data.
o  Data Call In Notices requesting
   registrants to generate the
   needed data on 6 EBDC's and
   ETU have been issued.

o  PD 1 published, 41 FR 31316
   (7/26/76);_comment period closed
   11/4/76:  NTIS# PB81 112690.
o  PD 2/3 completed and Notice of
   Proposed Determination pub-
   lished, 43 FR 51132  (11/2/78).
o  PD 4 published, (including can-
   cellations) 44 FR 43631  (7/25/79)
   NTISf PB81 10980.
                                             21

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                                     RPARS COMPLETED - Cont'd
                                                             June 1983
CHEMICAL {Class
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
Of
       40 CFR 162.11 CRITERIA
       POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
ENDRIN cont'
 (PM-15)
       o  Oncogenicity
       o  Teratogenicity
       o  Reduction in en-
          dangered species and
          nontarget species
GOAL
  (PM-25)
       o  Oncogenicity
PCNB
  Pentachloro-
  nitrobenzene
  (PM-21)
       o  Oncogenicity
o  PD 4 follow-up notice mailed
   8/28/80, cancellations began
   30 days later.
     - Some uses are conditionally
       registered because require-
       ments have been met.
o  Herb Harrison, Registration
   Division (557-2200) is contact
   point for inquiries.

o  PD 1/2/3 completed. NTIS# PB82
   172289.
o  PD 4 published in Federal
   Register on June 23, 1982;47 FR
   27118; NTIS# PB82 185133.
o  The decision is to continue use
   of the herbicide subject to
   certain restrictions (on PCE)
   pertaining to formulation of
   the product.

o  PD 1 published, 42 FR 61894
   (10/13/77); comment period closed
   2/6/78:  NTIS# PB80 216799
o  PD 2/3 in Agency review.
o  RPAR terminated through ne-
   gotiated agreement with regis-
   trants to reduce levels of the
   HCB contaminant and to make
   label changes to reduce ex-
   posure.  47 FR 18177, published
   4/19/82.

-------
                                    RPARs COMPLETED -  Cont'd
                                                      June 1983
CHEMICAL (Class
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
                ___
40 CFR 162.11 CRITERIA
POSSIBLY MET DR EXCEEDED
CURRENT
STATUS
PRONAMIDE
 (PM-25)
   o  Oncogenicity
   PD 1 published, 42 FR 32302
   (5/20/77); comment period closed
   8/29/77:  NTIS# PB81 109472.
   PD 2/3 completed and Notice of
   Proposed Determination published,
   44 FR 3083 (1/15/79); comment
   period closed 2/14/79:  NTIS#
   PB80 213911.
   PD 4 completed and Final Deter-
   mination published, 44 FR 61640
   (10/26/79): NTIS# PB81 112716.
   The following actions were
   taken:  Cancellation of regis-
   trations of products allowing
   hand spray applications, except
   for use on ornamentals and nur-
   sery stock; cancellation of
   registrations of products unless
   the registrant modifies the terms
   and conditions to allow certain
   uses of wettable powder products
   only by or under direct super-
   vision of certified applica-
   tors; modification of labeling of
   wettable powder products to in-
   clude specific general precau-
   tions, directions as to protective
   clothing to be worn, dilution
   instructions for wettable powder
   products, and watering instruc-
   tions for granular products used
   on turf; Agency revision of the
   lettuce tolerance from 2 ppm to
   Ippm; and required residue data on
   lettuce.
                                            23

-------
                                     RPARS COMPLETED -  Cont'd
                                                         June 1983
CHEMICAL (Class Of
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
THIOPHANATE METHYL
  (PM-21)
TOXAPHENE
  (PM-12)
o  Mutagenicity
o  Reduction in Non-
   target Species
   (Rebutted)
o  Oncogenicity
o .Population reduction
   non-target animal species
o  Acute toxicity to
   aquatic organisms
o  Chronic effects to
   wildlife
                                                      o
                                                      o
   PD 1 published, 42 PR 61940
   12/7/77); comment period closed
   3/27/78:  NTIS #PB80 216856
   PD 2 completeed and Notice of
   Proposed Determination pub-
   lished, 44 FR 58798 (10/11/79).
   PD 4 completed and Notice of
   Determination published, 47 FR
   46747 (10/20/82).  NTIS no.
   not available.  That determin-
   ation which included benomyl,
   required use of protective
   clothing and generation of
   additional data.

   PD 1 published, 42 FR 26860
   (5/27/77); comment period closed
   9/13/77: NTIS# PB80 216732.
   Decision Document published 11/29/83.
   Final Notice of Determination
   published in 47 FR 53784 (11/29/82).
   NTIS# PB 83- 144204.
   That notice presented the Agency
   decision to cancel registrations
   for most uses and continue regis-
   tration of certain uses under
   specific terms and conditions.
   The continued uses are:  corn,
   cotton and small grain for spe£if^ic
   insect infestation (emergency use
   only),  pineapples and bananas for
   specific insects in Puerto Rico
   and the Virgin Islands only, and
   scabies treatments of cattle and sheep

-------
                                     RPARs COM
                                  Cont'd
                  June 1983
CHEMICAL (Class "of"
Chemicals)  and
RESPONSIBLE
SPRD BRANCH
  40 CFR 162.11 CRITERIA
  POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
2,4,5-T/SILVEX
  (PM-22)
 or(PM-23)
TRIFLURALIN
Treflan
(PM-23)
 o  Oncogenicity
 o  Teratogenicity
 o  Fetotoxicity
o  Oncogenicity
o  Mutagenicity
  PD 4 completed and Final Deter-
  mination published, 44 FR 72316
  (12/13/79); applies to uses not
  included in suspension actions
  described on prior page under
  "Notice of Intent to Cancel
  Suspend Issued".

  PD 1/2/3/ published, 44 FR 50911
  (8/30/79); comment period closed
  11/13/79:  NTIS# PB80 213937.
  PD 4 published August 4, 1982,
  47 FR 33777:  Report #540/9-82-011;
  NTIS# PB82 263252.
  Trifluralin registrations allowed
  to continue if the total N-nitro-
  samine contamination is kept
  below 0.5 ppm for technical pro-
  ducts and below a figure based on
  trifluralin content for formulated
  products.
                                               25

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                   REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION
                                          June 1983
CHEMICAL (Class
of Chemicals)
      RESPONSIBLE
      RD BRANCH/PM
TYPE OF
CHEMICAL
AMITRAZ

BTC 2125

CAPTAN

Copper Sulfate & related hydrates

CYHEXATIN

DEMETON

3,5-Dibromosalicylanilide

DIFLUBENZURON

DIPROPETRYN

ENDRIN

EPN

GLYPHOSATE

HCL

HEXYLENE GLYCOL

HYAMINE 3500

METRIBUZIN

MONOCROTOPHOS
      I-R Branch/PM-12

Disinfectants Br./PM-31

      H-F Branch/PM-21

      H-F Branch/PM-21

      I-R Branch/PM-12

      I-R Branch/PM-16

Disinfectants Br./PM-32

      I-R Branch/PM-17

      H-F Branch/PM-25

      I-R Branch/PM-15

      I-R Branch/PM-12

      H-F Branch/PM-25

Disinfectants Br./PM-32

Disinfectants Br./PM-31

Disinfectants Branch/PM-31

     H-F Branch/PM-25

     I-R Branch/PM-16
Insecticide

Disinfectant

Fungicide

Fungicide

Insecticide

Insecticide

Disinfectant

Insecticide

Herbicide

Insecticide

Insecticide

Herbicide

Disinfectant

Disinfectant

Disinfectant

Herbicide

Insecticide

-------
                   REGISTRATION STANDARDS DEVELOPMENT - DATA  COLLECTION
                                           June 1983
CHEMICAL (Class
of Chemicals)
      RESPONSIBLE
      RD BRANCH/PM
TYPE OF
CHEMICAL
NAPTHALAM

NEOMYCIN SULFATE

NITRAPYRIN

OMADINE-SODIUM

ORYZALIN

PARATHION

POTASSIUM & SODIUM HYDROXIDE

POTASSIUM PERMANGANATE

SODIUM BISULFATE

SULFURYL FLUORIDE

TCC

THIOPHANATE Ethyl

THIOPHANATE Methyl
      H-F Branch/PM-25

      H-F Branch/PM-21

      H-F Branch/PM-23

Disinfectants Br./PM-32

      H-F Branch/PM-25

      I-R Branch/PM-12

Disinfectants Br./PM-32

Disinfectants Br./PM-32

Disinfectants Br./PM-32

      I-R Branch/PM-16

Disinfectants Br./PM-32

      H-F Branch/PM-21

      H-F Branch/PM-21
Herbicide

Disinfectant

Herbicide

Disinfectant

Herbicide

Insecticide

Disinfectant

Disinfectant

Disinfectant

Insecticide

Disinfectant

Fungicide

Fungicide
                                               27

-------
             REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND
                          DEVELOpMENT QF REGULATORY POSITION
                                             June 1983
CHEMICAL (Class
of Chemicals)
RESPONSIBLE
RD BRANCH/PM
TYPE OF
CHEMICAL
ACEPHATE

ALACHLOR

ALDICARB

AMITROLE

ANILAZINE

ARSENICALS

ATRAZINE

BENOMYL

BENTAZON(Na)(Basagram)

BUTYLATE

CAPTAFOL

CARBARYL

CARBOFENOTHION

CARBOFURAN

CHLORDIMEFORM/HCL

CHLOROBENZILATE
I-R Branch/PM-16

H-F Branch/PM-25

I-R Branch/PM-12

SR Branch

H-F Branch/PM-21

H-F Branch/PM-21

H-F Branch/PM-25

H-F Branch/PM-21

H-F Branch/PM-25

H-F Branch/PM-25

H-F Branch/PM-21

I-R Branch/PM-12

I-R Branch/PM-16

I-R Branch/PM-12

I-R Branch/PM-12

I-R Branch/PM-12
insecticide

Herbicide

Insecticide

Herbicide

Herbicide

Fungicide

Herbicide

Fungicide

Herbicide

Herbicide

Fungicide

Insecticide

Insecticide

Insecticide

insecticide

insecticide

-------
              REGISTRATION STANDARDS DEVELOPME
                E^T -
- DATA EVALUATION AND
June .1983
                           DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
of Chemicals)
CHLOROTHALONIL

CHLORPYRIFOS

CYANAZINE

DAMINO2IDE(Alar)

DCNA

DICAMBA

DICOFOL

DISULFOTON

DIURON

EPTC

FENAMINOSULF

FENSULFOTHION

FLUCHLORALIN (Basal in)

FONOFOS
RESPONSIBLE
RD BRANCH/PM
H-F Branch/PM-21

I-R Branch/PM-12

II-F Branch/PM-25

H-F Branch/PM-25

H-F Branch/PM-25

H-F Branch/PM-25

I-R Branch/PM-12

I-R Branch/PM-15

H-F Branch/PM-25

H-F Branch/PM-25

H-F Branch/PM-25

I-R Branch/PM-15

H-F Branch/PM-25

I-R Branch/PM-16
                TYPE OF
                CHEMICAL
                Herbicide

                Insecticide

                Herbicide

                Herbicide

                Herbicide

                Herbicide

                Insecticide

                Insectic ide

                Herbicide

                Herbicide

                Herbicide

                Insecticide

                Herbicide

                Insecticide
                                                 29

-------
               REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND
                            DEVELOPMENT OF REGULATORY POSITION
                                            June  1983
CHEMICAL (Class
of Chemicals)
      RESPONSIBLE
      RD DRANCH/PM
FORMETANATE HYDROCHLORIDE

HELIOTHIS

LINURON

NORFLCJRAZON

PENDIMETHALIN (Prowl)

PHORATE

PICLORAM

POTASSIUM Bifluoride

POTASSIUM BROMIDE

POTASSIUM IODATE

PROPACHLOR

SIMAZINE

TEBUTHIURON

THIRAM

TPTH(Triphenyltin Hydroxide)

TRICHLORFON
    I-R Branch/PM-12

    I-R Branch/PM-17

    H-F Branch/PM-25

    H-F Branch/PM-23

    H-F Branch/PM-25

    l-R Branch/PM-16

    SR Branch

Disinfectants Br./PM-32

Disinfectants Br./PM-32

Disinfectants Br./PM-32

    H-F Branch/PM-25

    H-F Granch/PM-23

    H-F Branch/PM-25

    H-F Branch/PM-21

    H-F Branch/PM-21

    I-R Branch/PM-16
TYPE OF
CHEMICAL
Insecticide

Insecticide

Herbicide

Herbicide

Herbicide

Insecticide

Herbicide

Dis infectant

Disinfectant

Disinfectant

Herbicide

Herbicide

Herbicide

Fungicide

Fungicide

Insecticide
                                             3 a

-------
                                 REGISTRATION STANDARDS -  ISSUED
                                                  June  1983
CHEMICAL S. REPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
ALUMINUM PHOSPHIDE
  (PM 16)
ALIETTE
 (PM-22)
 Insecticide
 Fung icide
 October 1981        11/24/81
 NTISI PB82 137514.  RS-81-017
                     PB82-137514

 June 30, 1983*
4-AMINOPYRIDINE  (AVITROL)
  (PM 16)
AMMONIUM SULFAMATE
   (PM 25)
AS PON
  (PM 16)

BARIUM METABORATE
  (PM-22)
 Bird Chemosteri-
   lants. Toxicants
   and Repellents

 Herbicide
 Insecticide
 Fungicide
 September 1980*
 June 1981
 NTIS* PB82 133570,
 September 1980*
 NTIS# PB81 112484,

 April 14, 1983*
 9/30/80
                                                                                    * *
 8/5/81
 RS-81-Q12
 PB82-133570,

 9/30/80**.
 6/27/83'
 BIFENOX
   (PM  25)

 BKLFI-2
   (PM-3 2)

 80LSTAR  (SULPROFOS)
   (PM-12)
  Herbicide


  Disinfectant


  Insecticide
 BORIC  ACID  (pending  25(b)  exemption decision)
   (PM-16)

 *  RS or  NTIS PB number  not available.
 ** NTIS  numbers not  available.
 June 1981*
 December  1981*
 August  1981
 NTIS# PB82  133646
 8/12/81
 RS-82-007**

 12/29/81
 RS-82-002/**

 3/10/81
 RS-81-008
 PB-32-133646
                   31

-------
                              REGISTRATION STANDARDS - ISSUED Cont'd
                                              June  1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM}  IN
REGISTRATION DIVISION
8ROMAC[L & SALTS
  (PM 25)

CARBOXIN (VITAVAX®)
  (PM 21)
CflLORAMBEN
  (PM 25)
CHLORONEB
  (PM 21)

CHLOROPICRIN
  (PM 21)
TYPE OF
CHEMICAL
Herbicide


Fungic Lde


Herbicide


Fungicide


Insecticide
DATE OF
STANDARD
& NTIS NOS.
August 1981
NTIS# PB82 132994
August 1981
NTIS# PB82 134347
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
September 1982*     9/30/82
                                                                                    * *
8/12/81
RS-31-007
PB82-132994,

8/12/81
RS-81-015
PB82-134347
September 1980      9/30/80
NTISf PB81 123804.
                                                                                    **
September 1982*     9/28/82
                            * *
COUMAPHOS
  (PM 15)
CRYOLITE
 (PM-17)

CYCLOHEXIMIDE
   (PM 21)

DEBT
   (PM 25)
Insecticide



Insecticide


Fungicide


Insecticide
August 1981          9/4/81
NTISt PB82 133570.   RS-81-013
                     PB82-133357.
June 23, 1983*
December  1980*
June  28,  1983**
September  1982*      9/24/82**,
 12/2/80*
 RS-81-004
* RS or NTIS PB number not available.
** NTIS numbers not available.
                                                  32

-------
                             REGISTRATION  STANDARDS -  ISSUED Cont'd
                                             June 1983

CHEMICAL & RESPONSIBLE
PRODUCT MANAGER 
-------
                            REGISTRATION STANDARDS - ISSUED Cont'd
                                             June 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
RtGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
FUMARIN (COUMAFURYL)
  (PM 16)

GLEAN® (CHLOROSULFURON)
  (PM 25)

HEXAZINONE (VELPAR)
  (PM 23)

HYPOCHLORITE Salts
  (PM-32)

ISOPROPALIN
  (PM 25)

MAGNESIUM PHOSPHIDE
  (PM 16)

MCPA
  (PM 23)

METALAXYL (RIDOMIL®)
  (PM 21)

METHAMIDOPHOS  (MONITOR®)
  (PM 16)

METHIDATHION
  (PM-12)

METHOMYL
  (PM 12)
Rodent Toxicant
and Anticoagulant

Herbicide
Herbicide


Disinfectant


Herbicide


Insecticide


Herbicide


Fungicide


insecticide


Insecticide


Insecticide
September 1982
NTIS# PB81 123812,

September 1982.
February 1982.
January 13, 1983
August 1981
NTIS# PB82 131293,

March 1982
NTIS# PB82 195777,

March 1982.
August 1981
NTIS# PB82 172297.

September 1982
January 13, 1983
10/21/80**.
9/30/82**.
4/27/82**.
8/5/81
RS-81-009
PB82-131293,
3/29/82
RS-82-006
PB82-195777,
6/30/82**.
8/31/81 "
RS-82-005
PB82-172297,
9/24/82**.
1/14/83
September 1981       1/22/82
NTIS# PB82 180738.   RS-82-001
 *  RS or  NTIS  PB  number  not  available
 ** NTIS  numbers  not  available
                                                 34

-------
                              REGISTRATION STANDARDS - ISSUED Cont'd
                                             June 1983

CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
METHOPRENE
(PM 17)
METOLACHLOR
(PM 23)
MONURON
(PM-25)
MONURON TCA
(PM-25)
NALED
(PM-16)
NAPHTHALENE
(PM 16)
NAPHTHALENEACETIC ACID
AND ITS SALTS
(PM 25)
OBPA (10, 10'-
OXYBISPHENARAZINE)
(PM 21)
PHOS ALONE
(PM 12)
TYPE OF
CHEMICAL
Insecticide
Herbicide
Herbicide
Herbicide
Inseticide
Insecticide
Growth Regulator
Fungicide
Insecticide
DATE OF
STANDARD
& NTIS NOS.
February 1982*
September 1980*
NTIS# PB81 123820.
June 30, 1983*
June 30, 1983*
June 30 , 1983*
September 1981
NTIS# PB82 139437.
August 1981
NTIS IPB82 131145.
September 1981
NTIS* PB82 172271.
September 1981.
NTIS* PB82 131731
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
3/31/82**.
9/30/80**
7/7/83**
7/7/83**
7/6/83**
11/9/8.1
RS-81-016
PB82-139437.
8/18/81
RS-81-006
PB82-131145.
10/27/81
RS-82-003
PB82-172271.
9/18/81
RS-81-010**
PLANTPIN® (BUTOXICARBOXIME)
  (PM 12)
Insecticide
September 1981
NTIS# PB82 177585,
9/30/81
RS-82-004
PB82-177585.
* RS or NTIS PB number not available
** NTIS numbers not available
                                              35

-------
                              REGISTRATION STANDARDS - ISSUED Cont'd
                                             June 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
SULFUR
  (PM 22)

SULPROFOS (BOLSTAR)
  (PM-12)
TEMEPHOS (ABATE)
  (PM-16)

TERBACIL
  (PM-25)

TERBUFOS
  (PM-16)

TERRAZOLE
  (PM 21)
WARFARIN
   (PM 16)
ZINC PHOSPHIDE
   (PM 16)
Fungicide


Insecticide



Insecticide



Herbicide

Insecticide


Fungicide
Rodent Toxicant &
Anticoagulant
Rodent Toxicant and
Anticoagulant
December 1982*
August 1981
NTIS# PB82 133646,
August 1981
NTIS# PB82 140641,
June 4, 1982*

June 30, 1983*
September 1980
NTIS* PB81 126716,
August 1981
NTIS# PB82 140716
June 1982*
12/29/82**


8/10/81
RS-81-008
PB82-133646

9/25/81
RS-81-018
PB82-140641

6/4/82**

6/30/83**
9/30/80
OPP-80-525
PB81-126716,

10/26/81
RS-81-019
PB82-140716,

6/23/82**.
 *  RS or NTIS  PB  number  not  available
 **  NTIS numbers  not available

-------
                                                                           June 1983
                            DATA CALL IN — STATUS OF CHEMICALS
The following chemical clusters are being processed through Data Call In (DCI).
These clusters are the same as described in the Federal Register notice on
November 14, 1980 (45 FR 75488), except that the chemicals now in Registration Standard
development or in the RPAR process are omitted.  The status of these clusters and the
chemicals are as follows.

DCI Cluster #1 consists of insecticides used on corn, alfalfa and sorghum (1-2)

     Chemical                       Status
     Bufencarb
     Carbofuran
     Carbophenothion
     Chlorpyrifos
     Disulfoton
     Ethoprop
     Fensulfothion
     Fonofos
     Landrin (Broot)
     Phorate
     TEPP
     Terbufos
     Trichlorfon
Decision reached - cancelled/suspended.
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated
Decision reached - chronic data being generated
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - suspended.
Decision reached - temporary data waiver.
Decision reached - chronic data base complete.
 "Letter being drafted" -- the Agency is investigating the available chronic studies and
discussing the findings with registrants.

 "Letter issued (date)" — The notice/notification or equivalent was issued to  indicate
existing chronic data gaps.

 "Decision reached" — The Agency has evaluated all  the  responses  from  registrants  reques-
 ting exemptions, waivers, commitments, offers to cost share, cancellations, suspensions,
 etc. and has issued final decisions on the data required and status of all registrations
 containing the chemical.  The terms "chronic data being generated" or  "chronic data
 waiver or deferral" are self explanatory. "Chronic  data base complete" may mean  that the
 data were available, recently submitted, or certain data requirements  have been  waived.
 The terms "cancelled", "suspended", "no current registrations" mean that  there are no
 known active registrations of the chemicals.  The term  "Defer requirements to  Standard"
 means that the standard is planned to be developed  within two years hence and  the  chronic
 requirements will be addressed  in the standard.
                                             37

-------
                        DATA CALL IN — STATUS OF CHEMICALS COnt'd
                                                                           June 1983
Data Call In Cluster #2 consists of insecticides used on citrus and grapes (1-4).

       Chemical                    Status
    Chlorobenzilate
    Cryolite
    Dimethoate
    Dioxothion
    Ethion
    Formetanate hydrochloride
    Naled
    Tetrad ifon

Data Call In Cluster #3 consists
wheat and tobacco (1-1).

    Aldicarb
    Bollex
    Chlordimeform
    Chlordimeform hydrochloride
    Demeton
    Dimilin
    Endrin
    Fenvalerate
    Gossyplure
    Grandlure
    Heliothis virus
    Methyl Parathion
    Monocrotophos
    Parathion
    Permethrin
    Phosphamidon
  Decision reached
  Decision reached
  Decision reached
  Decision reached
  Decision reached
  Decision reached
  Decision reached
  Decision reached
chronic data being generated.
chronic data deferred.
chronic data base being generated,
chronic data being generated.
chronic data being generated.
chronic data deferred.
chronic data being generated.
suspended.
of insecticides used on cotton, soybeans, peanuts,
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Decision reached - chronic
  Letter issued 11/14/81.
  Decision reached - chronic
  Decision reached - chronic
        data being generated.
        data base complete.
        data base complete.
        data base complete.
        data being generated.
        data base complete.
        data base complete.
        data base complete.
        data base complete.
        data base complete.
        data base complete.
        data being generated.
        data being generated.

        data base complete.
        data being generated.
                                            38

-------
                        DATA CALL IN — STATUS OF CHEMICALS cont'd

Data Call In Cluster #4 consists of herbicides used on corn (H-2).
                                                                           June 1983
   Alachlor
   Atrazine
   Butylate
   Cyanazine
   Cyprazine
   Dicamba
   EPTC
   Simazine
   TCBC
Decision reached - chronic data base complete.
Letter issued 7/26/82
Decision reached - chronic data being generated.
Letter issued 7/12/82.
Decision reached - Suspension/Cancellation.
Letter issued 9/28/82.
Decision reached - chronic data being generated.
Letter issued 12/2/82.
Decision reached - cancelled/suspended.
Data Call In Cluster #5 consists of herbicides used on soybeans, cotton, peanuts and
alfalfa (H-3).
   Acifluorfen
   Bentazon
   Sodium Bentazon
   Dichlofop methyl
   Dinitramine
   Dipropetryn
   DSMA
   EGT
   Fluchloralin
   Glyphosate isopropylamine salt
   Metribuzin
   Naptalam
   Nitralin
   Norflurazon
   Oryzalin
   Oxyfluoren
   Pendimethalin
   Perfluidone
   Profluralin
   Pronamide
   Propachlor
   Vernolate
   2,4-DB
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Decision reached - chronic data base to be generated,
Letter issued 3/31/83.
Letter issued 8/18/82.
Decision reached - cancelled.
Letter issued 12/1/82.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - Defer requirements to standard.
Decision reached - cancelled.
Letter issued 6/29/83.
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Letter issued 9/7/82.
Decision reached - No added data required.
Decision reached - cancelled.
Decision reached - chronic data being generated.
Letter issued 1/19/83
Decision reached - chronic data being generated.
Letter issued 10/22/82.
                                            39

-------
                        DATA CALL IN — STATUS OF CHEMICALS cont'd

Data Call in Cluster #6 consists of fungicides used on vegetables (F-3).
                                                                           June 1983
Anilazine
Calcium Cyanamide
DCNA
Hexachlorophene
Triad imefon
Decision reached - Defer requirements to standard.
Letter being drafted.
Decision reached - Defer requirements to standard.
Letter deferred.
Decision reached - chronic data base complete.
Special Data Call In Fungicide Project consists of certain large volume fungicides which
will be processed through Data Call In and subjected to comparative risk analysis.
Captafol
Chlorothalonil
Dinocap
Dodine
Ferbam
Folpet
Th i ram
Copper (Bordeaux mixture)
Copper Carbonate
Copper Naphthenate
Copper Oxide
Copper Oxychloride
Copper Quinolinolate
Copper Sulfate Basic
Copper Sulfate Monohydrate
Decision reached - chronic
Letter issued 9/14/81.
Decision reached - chronic
Decision reached - chronic
Letter issued 9/4/81.
Letter issued 9/4/81.
Decision reached - chronic
Decision feached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
data being generated.

data being generated.
data base complete.
data base complete.
data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
data waived.
Special Data Call In Fumigant Project.
listed above but for fumigants.
    Same as Special Data Call In Fungicide Project
Carbon disulfide
Ethylene dichloride
Methyl Bromide
Decision reached - time extension on initiating studies
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
                                            40

-------
                                                                            June 1983
                         DATA CALL IN — STATUS OF CHEMICALS cont'd
                                     Letter issued 3/I6/R3
RPAR Decision Data Call In
      Benomyl
      EBDC'S
        Nabam
        Amobam
        Metiram
        Zineb
        Maneb
        Mancozeb
      Piperonyl Butoxide
      TrefIan

R-7  Wood preservatives for industrial, commercial and marine use.

      Potassium bifluoride           Decision reached - Defer requirements to  standard

F-5  Fungicides used as seed treatments
Letter
Letter
Letter
Letter
Letter
Letter
Letter
Letter
issued
issued
issued
issued
issued
issued
issued
issued
1 ,/8 3 .
1/83.
1/83.
1/83.
1/83.
1/83.
9/30/82
8/25/82
      Hexachlorobenzene
      Fenaminosulf
      Chloronitropropane
                                     Decision reached - Letter deferred
                                     Decision reached - Defer requirements  to  standard.
                                     Decision reached - Cancelled/discontinued.
R-ll Preservatives,  disinfectants, slimicides, unclassified uses.

       Chromic acid
       Chlorobenzene
       Omad i ne- sod i urn
       Dowicil A-40
       Dowicide 31,32
       Nitrapyrin
       Hexylene glycol
       Abietylamine
       Lime
       Potassium iodate
       Potassium permanganate
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
De c i s i on
Decision
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
- NO
- No
- No
- NO
- NO
- NO
- No
- No
- NO
- No
- No
added
added
added
added
added
added
added
added
added
added
added
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
data
data
data
data
data
data
data
data
data
data
data
needed
needed
needed
needed
needed
needed
needed
needed
needed
needed
needed
now
now
now
now.
now.
now.
now.
now.
now.
now.
now.
                                                41

-------
                                                                           June 1983
                DATA CALL IN —STATUS OF CHEMICALS cont'd
1-3  Insecticides used on fruit and nut trees excluding citrus and grapes,
      Azinphos methyl
      Chloropropylate
      Cyhexatin
      Diazinon
      2-naphthol
      Ovex
      Phosmet
      Propargite
      Tetrasul
      Vendex
      Dormant oil
Decision reached - chronic data base complete.
Decision reached - cancelled/discontinued.
Letter issued 6/17/83.
Letter issued 2/18/83.
Decision reached - no added chronic data needed,
Decision reached - cancelled/discontinued.
Letter issued 6/20/83.
Decision reached - chronic data base complete.
Letter being drafted.
Letter being drafted.
Letter being drafted.
H-4  Herbicides used on sorghum, rice and small grains,
       Bromoxynil
       Difenzoquat
       Methazole
       Propanil
       Picloram
       Barban
       Terbutryn
       Propazine
       Triallate
       Butachlor
       Molinate
       Oxadiazon
Letter issued 1/19/83.
Letter being drafted.
Letter being drafted.
Letter issued 6/20/83
Decision reached - defer rqmts. to standard.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Decision reached - cancelled/discontinued
Letter being drafted.
Letter being drafted.

-------
                                                                           June 1983
                     DATA  CALL  IN  —  STATUS  OF  CHEMICALS  cont'd
1-5  Insecticides  used  on  vegetables.

      Bacillus  thuringiensis
      Malathion
      Methoxychlor
      Mevinphos
      Nicotine
      Nicotine  sulfate
      Oxamyl
      Pirimicarb
      Rotenone
      Ryanodine
      Sabadilla alkaloids
      Oxyderaeton methyl
      Pirimiphos ethyl
Decision reached - chronic data base complete,
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drated.
Letter being drafted.
Letter being drafted.
Decision reached - cancelled/discontinued.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
      Pinmipnos etnyi                   Letter being dratted.

H-5 Herbicides used on  citrus,  tree fruits, nuts, and sugar cane.

      Ametrvn                           Letter beina drafted.
      Ametryn
      Paraquat
      Dichlobenil
      Napropamide
      Asulam
      Hexazinone
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Decision reached - Defer rqmts. to standard.
H-9  Herbicides used on vegetables and tobacco.
      Nitrofen
      Endothall
      Diphenamid
      Chlorpropham
      Bisethylxanthogen
      CDAA
      Prometryn
Letter
Letter
Letter
Letter
Letter
Letter
Letter
                                               being
                                               being
                                               being
                                               being
                                               being
                                               being
                                               being
drafted.
drafted.
drafted.
drafted.
drafted,
drafted,
drafted,
                                         43

-------
                        DATA CALL IN -- STATUS OF CHEMICALS cont'd

F-2   Fungicides used on walnuts, pecans, almonds, apples, pears,
      peaches,  cherries, plums, prunes, and  grapes.
                                                                           June 1983
      Ammonium Polysulfide
      Dithianon
      2,2- Dithiobisbenzothiazole
      Fentin hydroxide
      Glyodin
      Karathane
      Oxythioquinox
      Sodium Polysulfide
      Streptomycin
      Ziram
Letter being drafted.
Letter being drafted.
Letter being drafted.
Decision reached - Defer rqmts. to standard
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
H-6   Herbicides used on sugar beets, beans and peas.
      Cycloate
      DaLapon
      Desmedipham
      Diallate
      Dinoseb
      Ethofumesate
      MCPB
      Pebulate
      Phenmedipham
      Propham
      Pyrazon
      Sodium TCA
Letter being drafted.
Letter being drafted.
Letter being drafted.
Decision reached - Defer rqmts. to standard
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter being drafted.
H-7   Herbicides used on drainage ditches, rights of way, forestry
      and ponds.
      Acrolein
      Amitrol
      Dichlorprop
      Diquat
      Fenac
        rbutilate
Letter
Letter
Letter
Letter
Letter
Letter
                                           44
being
being
being
being
being
being
drafted.
drafted.
drafted.
drafted.
drafted,
drafted.

-------
                                                                           June 1983
       MAMA
       MSMA
       Prometon
       Trichlopyr
             DATA CALL IN — STATUS OF CHEMICALS cont'd

                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
1-12   Insecticides used as mosquito larvicides.
       Fenthion
       Kerosene
       Dimethrin
                                  Letter being drafted,
                                  Letter being drafted,
                                  Letter being drafted,
1-6
Insecticides used on livestock and domestic animals.
       Benzyl Benzoate
       Bomyl
       Bone oil
       Butonate
       Butoxy Polypropylene glycol
       Chlorfenvinphos
       Crotoxyphos
       Crufornate
       Dichlorvos
       Diisobutyl  Phenoxyethanol
       Diphenylamine
       Famphur
       Lindane
       Linseed Oil
       Muscalure
       Phenothiazine
       Piperazine  dihydrochloride
       Tabutrex
       Tetrachlorvinphos
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter issued - 3/22/83
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                  Letter being drafted.
                                          45

-------

-------
                                                    INDH!^
                                     Page

Abate® see Temephos
Abietylamine  S #004101                41
  CAS #51344-60-6
Acephate  S #103301                    28
  CAS #30560-19-1
Acifluorfen S #114401, 114402, 114403  39
  CAS # for following compounds
      sodium salt 62476-59-9
      ethyl ester 77207-01-3
Acrylonitrile  S #000601                7
  CAS #107-13-1
Acrolein S #000701                     44
  CAS #107-02-8
Alachlor  S #090501               28 & 39
  CAS #15972-60-8
Alar® see Daminozide
Aldicarb  S #098301, 110801            38
  CAS #116-06-3
Aldrin/Dieldrin  S #45101/45001         9
  CAS #309-00-2—60-57-1
Aliette  S #123301                     31
  CAS #none
Aluminum phosphide  S #066501          31
  CAS #20859-73-8
Ametryn  S #080801                     43
  CAS #834-12-8
4-Aminopyridine  S #069201             31
  (Avitrol®)
  CAS #504-24-5
Amitrole  S #004401               28 & 44
  CAS #61-82-5
Amitraz  S #106201, 572200        17 & 26
  CAS #33089-61-1
Ammonium polysulf ide  S #076701        44
  CAS #9080-17-5
Ammonium sulfamate  S #005501          31
  CAS #7773-06-0
Amobam  S #014502
  CAS #3566-10-7
Anilazine  S #080811
  CAS #101-05-3
Arsenicals  S # Multiple
  CAS # Multiple
Arsenic trioxide  S #007001
  CAS #1327-53-3
Aspon®  S #079101
  CAS #3244-90-4
Asulam  S #106901
  CAS #3337-71-1
Atrazine  S #080803
  CAS #1912-24-9
Avitrol®  see 4-Aminopyridine
Azinphos methyl  S #058001
  CAS #86-50-0
Bacillus thuringiensis  S #006401
  CAS #68038-71-1
Barban  S #017601
  CAS #101-27-9
Barium Metaborate  S #011101
  CAS #13701-59-2
Basic Copper arsenate S #271300
  CAS #10103-03-8
Bencmyl  S #099101
  CAS #17804-35-2
Bentazon  S #275200, 103901
  CAS #25057-89-0
Benzene  S #008801
  CAS #71-43-25-2
Benzyl benzoate  S #009501
  CAS #120-51-4
BHC  S #008901
  CAS # mixed isoners 608-73-1
  alpha 319-84-6
  beta 319-85-7
   28
   28
   Page

     41

   & 40

     28

      7

     31

     43

   & 39


     42
        42

        31

         7

18,28 & 41

      & 39

         7

        45

         7
28

-------
                                     Page
                                     Page
  delta 319-86-8
  epsilon 6108-10-7
  zeta 6108-11-8
  eta 6108-12-9
Bidrin® see Dicrotcphos
Bifenox S #104301, 285200              31
  CAS #42576-02-3
Bisethylxanthogen  S #086501           43
  CAS #502-55-6
BKIfI-2  S #046924                     31
  CAS #82010-75-1
Bollex  S #118501                      38
  CAS #4175-47-7
Bolstar®  see Sulprofos
Bcmyl  S #084201                       45
  CAS #122-10-1
Bone Oil  S #010801                    45
  CAS #8001-85-2
Boric acid  S #011001                  31
  CAS #10043-35-3
Bronacil & salts S #012301,  02,       32
                    03, 04
  CAS #314-40-9
  lithiumbrcmacil #534-19-6
Brcmoxynil  S #035301                  42
  CAS #1689-84-5
BTC 2125  S #'s 069104,069111          26
  CAS #'s 1871-22-3,42988-44-3
Bufencarb  S #059301                   37
  CAS #8065-36-9
Butachlor  S #112301                   42
  CAS #23184-66-9
Butonate  S #035701                    45
  CAS #126-22-7
Batoxicarboxime  see Plantpin®
Butoxy polypropylene glycol  S #011901 45
  CAS #9007-07-2
Butylate  S #041405               28 & 39
  CAS #2008-41-5
Cacodylic acid & salts  S #012501      11
  CAS #75-60-5
  Sodium cacodylate 124-65-2
Cadmium  S #021001, 02, 05              1
         012901, 02,  236200,
         012903, 04, 05
  CAS # for following compounds
  anilocadmium dilactate 19651-91-3
  cadmium chloride 10108-64-2
  cadmium succinate 141-00-4
  cadmium sebacate 4476-04-4
Calcium cyanamide  S #014001           40
  CAS #156-62-7
Captafol  S #081701               28 & 40
  CAS #2425-06-1
Captan  S #081301                  1 & 26
  CAS #133-06-2
Carbaryl  S #056801               11 & 28
  CAS #63-25-2
Carbofenothion  S #058102              28
  CAS #786-19-6
Carbofuran  S #090601             28 & 37
  CAS #1563-66-2
Carbon disulfide  S #016401            40
  CAS #75-15-0
Carbon tetrachloride  S #016501         1
  CAS #56-23-5
Carbcphenothion  S #058102        28 & 37
  CAS #786-19-6
Carboxin (Vitavax®) S #090201          32
  CAS #5234-68-4
CDAA  S #019301                        43
  CAS #93-71-0
Chloramben S #029901, 02, 03, 04,      32
              05, 06
  CAS #133-90-4

-------
                                     Page
Chloranil S #079301
  CAS #118-75-2
Chlordane/Heptachlor
  chlordane  S #058201
  CAS #54-74-9 (cp)
       12789-03-6 (tech)
  CAS #76-44-8
  heptachor  S #044801
    CAS #76-44-8
Chlordecone (Kepone) S #027701
  CAS #143-50-0
Chlordimeform  S #059701
  CAS #6164-98-3
Chlordimeform/hydrochloride
  CAS #19750-95-9
Chlorfenvinphos  S #084101
  CAS #470-90-6
Chlorobenzene  S #056504
  CAS #108-90-7
Chlorobenzilate
  CAS #510-15-6
Chloroform   S #020701
  CAS #67-66-3
Chloroneb   S #027301
  CAS #2675-77-6
Chloronitrcpropane  S #011302
  CAS #2425-66-3
Chlorcpicrin  S #081501
  CAS #76-06-2
Chlorqpropylate  S #026801
  CAS #5836-10-2
Chlorothalonil  S #081901
  CAS #1897-45-6
Chlorprophan  S #018301
  CAS #101-21-3
Chlorpyrifos  S #059101
  CAS #2921-88-2
                   7 & 9

                 12 & 38

            S #059702 28 &
                        38
                      45

                      41
S #028801    19, 28 & 38
                      12
                      32
                      41
                      32
                      42
                 29 & 40
                      43
                 29 & 37
Chromic acid  S #021101
  CAS #7738-94-5
Coal tar  S #022003
  CAS #8007-45-2
Copper acetoarsenite  S #022601
  CAS #12002-03-8
Copper (bordeaux mixture)  S #
  CAS #8011-63-0
Copper carbonate  S #022901
  CAS #12069-69-1
Copper naphthenate  S #023102
  CAS #1338-02-9
Copper oxide  S #025601
  CAS #1317-38-0 & 1317-39-1
Copper oxychloride  S #023501
  CAS #8012-69-9
Copper quinolinolate  S #024002
  CAS #10380-28-6
Copper sulfate basic  S #024401
  CAS #1344-73-6
Copper sulfate monohydrate S #024402
  CAS #10237-72-6
Coumafuryl  see Fumarin®
Coumsphos  S #036501
  CAS #56-72-4
Creosote  S #025004
  CAS #8021-39-4
Crotoxyphos  S #058801
  CAS #7700-17-6
Crufonate  S #012101
  CAS #299-86-5
Cryolite   S #075101
  CAS #15096-52-3
Cyanazine  S #100101
  CAS #21725-46-2
Cycloate  S #041301
  CAS #1134-23-2


1







26
02




32
29

Page
41
& 26
7
40
40
40
40
40
40
& 40
26 &
40
32
2
45
45
& 38
& 39
44

-------
                                     Page
                                     Page
Cycloheximide  S #043401               32
  CAS #66-81-9
Cyhexatin  S #101601              26 & 42
  CAS #13121-70-5
Cyprazine  S #100401                   39
  CAS #22936-86-3
Dalapon  S #'s 028901,2,3,4            44
  CAS #75-99-0
Daminozide (Alar®)  S #035101          29
  CAS #1596-84-5
Dasanit  see Fensulfothion
2,4-DB  S #030801
  CAS #94-82-6
DBCP  S #011301
  CAS #96-12-8
DCNA  S #031301
  CAS #99-30-9
ODD  S #029101
  CAS #72-54-8
DDT  S #029201
  CAS #50-29-3
Deet  S #080301
  CAS 134-62-4
Demeton  S #057601
  CAS 8065-48-3
Desmedipham  S #104801
  CAS #13684-56-5
Dialifor  S #102501
  CAS #10311-84-9
Diallate S #078801
  CAS #2303-16-4
      cis #17708-58-6
      trans #17708-57-5
Diazinon  S #057801                    42
  CAS #333-41-5
Dibronosalicylanilide  S #077402       26
  CAS #87-12-7

9
29



26


33
39
& 19
& 40
9
9
32
& 38
44
33
& 44
Dicamba S #029801, 02, 03,        29 & 39
              04, 05, 06
  CAS #1918-00-9
Dichlobenil  S #027401
  CAS #1194-65-6
Diclofop methyl  S #110902
  CAS # 51338-27-3
Dichlone   S #029601
  CAS #117-80-6
Dichlorprcp  S #031401
  CAS #120-36-5
Dichlorvos  S #084001
  CAS #62-73-7
Dioofol  see Kelthane*
Dicrotcphos S #035201
  CAS #141-66-2
Dieldrin  see Aldrin/Dieldrin
Difenzoquat  S #106401
  CAS #43222-48-6
Diflubenzuron (Dimilin) S #108201   12&26
  CAS #35367-38-5
Diisobutyl phenoxyethanol  S #001504
  CAS #121-54-0
Dimethoate  S #035001
  CAS #60-51-5
Dimethrin  S #034101
  CAS #70-38-2
Dimilin  S #108201
  CAS #35367-38-5
Dinitramine  S #102301
  CAS #29091-05-2
Dinocap  S #036001
  CAS #39300-45-3
Dinoseb  S #'s 037511,2,3,4;037505,6
  CAS #88-85-7
Dioxathion  S #037801             33 & 38
  CAS #78-34-2
         43
         39
         33
         44
    12 & 45
         33
         42
         45
20, 33 & 38

         45
         38
     9 & 39
         40
         44

-------
                                     Page

Diphenamid  S #036601                  43
  CAS #957-51-7
Diphenylamine  S #038501               45
  CAS #122-39-4
Diprcpetryn  S #104401            26 &  39
  CAS #4147-51-7
Diquat  S #032201                      44
  CAS #85-00-7
Disulfoton  S #032501             29 &  37
  CAS #298-04-4
Dithianon  S #099201                   44
  CAS #3347-22-6
2,2-Dithiobisbenzothiazole S #009202   44
  CAS #120-78-5
Diuron  S #035505                      29
  CAS #330-54-1
Dodine  S #044301                      40
  CAS #2439-10-3
Dormant oil  S # none                  42
  CAS # none
Dowicide 31:32  S #062208, 10          41
  CAS #607-12-5
Dowicil A-40 S #102801                 41
  CAS #38827-35-9
DSMA  S #013802                        39
  CAS #144-21-8
EBDC's  S #014502, 03, 05,        21 &  41
           06, 014601
  CAS #111-54-6
  see  amobam, maneb, nabam,
       mancozeb, metiram,
       zineb
EOT S #042201                          39
  CAS #2514-53-6
Endosulfan S #079401                   33
  CAS #115-29-7-1
Endothall  S #'s 038901,2,3,4,5,6,7;   43
  CAS #129-67-9
                                     Page

Endrin  S #041601            9,21,26 & 38
  CAS #72-20-8
EPN  S #041801                     2 & 26
  CAS #2104-65-4
EPTC  S #041401                   29 & 39
  CAS #759-94-4
Erbon  S #028701                        7
  CAS #136-25-4
Ethion  S #058401                 33 & 38
  CAS #563-12-2
Ethofumesate  S #110601                44
  CAS #26225-79-6
Ethoprop  S #041101               33 & 37
  CAS #13194-84-4
Ethoxyquin  S #055501                  33
  CAS #91-53-2
2-Ethyl-l,3-hexanediol S #041001       33
  CAS #94-96-2
Ethylene dibronide  S #042002           2
  CAS #106-93-1
Ethylene dichloride  S #042003         40
  CAS #107-06-2
Ethylene oxide  S #042301               2
  CAS #75-21-8
Fanphur  S #059901                     45
  CAS #52-85-7
Fenac  S #082601                       44
  CAS #85-34-7
Fenaminosulf  S #034201           29 & 41
  CAS #140-56-7
Fensulfothion   S #032701         29 & 37
  CAS #115-90-2
Fenthion  S #053301                    45
  CAS #55-38-9
Fentin hydroxide  S #083601            44
  CAS #76-87-9
Fenvalerate  S #109301                 38
  CAS #51630-58-1

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                                     Page
                                     Page
Ferban  S #034801                      40
  CAS #14484-64-1
Fluchloralin S #108701            29 & 39
  CAS #33245-39-5
flolpet  S #081601                      40
  CAS #133-07-3
Ponofos  S #041701                29 & 37
  CAS #944-22-9
Fbrmetanate hydrochloride         30 & 38
  S #465200
  CAS #22259-30-9
Fumarin® (Coumafuryl) S #086001        34
  CAS #117-52-2
Glean  S #118601                       34
  CAS #38641-94-0
Glyodin  S #043601                     44
  CAS #556-22-9
Glyphosate iscpropylamine
  salt  S #103601                 26 & 39
  CAS #38641-94-0
Goal  S #111601                        22
  CAS # 42874-03-3
Gossyplure*  S #114101, 02             38
  CAS # 53042-79-8, 52207-99-5
Grandlure®  S #112401, 02, 03, 04      38
  CAS #11104-05-5
HCL  S #045901                         26
  CAS #7647-01-0
Heliothis virus  S #107301        30 & 38
  CAS # none
Heptachlor  see Chlordane Heptachlor
Hexachlorobenzene  S #061001           41
  CAS #118-74-1
Hexachlorcphene  S #044901             40
  CAS #70-30-4
Hexazinone (Velpar®)  S #107201   34 & 43
  CAS #51235-04-2
Hexylene glycol  S #068601        26 & 41
  CAS #107-41-5
Hyamine 3500  S #069105                26
  CAS # None
Hypochlorites  S #014701, 02, 03       34
  CAS # for following compounds
  sodium 7681-52-9
  calcium 7778-54-3
  lithium 13840-33-0
Inorganic arsenicals               3 & 28
  S #006801, 02 006901, 007001
  CAS # for following compounds
  arsenic acid 1327-52-2 & 7778-39-4
  arsenic pertoxide 1303-28-2
  arsenic trioxide 1327-53-3
  sodium arsenate 7631-89-2, 10103-60-3,
  13464-38-5 & 35794-26-4
  ammonium arsenite 58829095-1
  sodium pyroarsenate 13464-42-1
  lead arsenate (basic) 3687-31-8
  lead arsenate 7645-25-2, 7784-40-9 &
  10102-48-4
  calcium arsenate 7778-44-1
  sodium arsenite 7784-46-5
  copper acetoarsenite 12002-03-8
Isocyanurates  S #081401, 03, 04, 05,   8
                  06, 07
  CAS #126-25-4
  isocyanuric acid 108-80-5
  isocyanuric chloride 87-90-1
  sodium isocyanurate 2624-17-1
  potassium dichloroisocyanurate 2244-21-5
  sodium dichloroisocyanurate 2893-78-9
  sodium trichloroisocyanurate 29680-41-9
  triphenyl isocyanurante 1785-02-0
  isocyanuric dichloride 2782-57-2
  isocyanuric dichloride,
    dihydrate 515 80-86-0

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                                     Page

Iscprcpalin  S #100201                 34
  CAS #33820-53-0
Karathane  S #036001                   44
  CAS #131-72-6
Karbutilate  S #097401                 44
  CAS #4849-32-5
Kelthane® (Dioofol)   S #010501         29
  CAS #115-32-2
Kepone  see Chlordecone
Kerosene  S #063501                     45
  CAS #8008-20-6
Landrin  S #102401,  02                 37
  CAS #2686-99-9
Lime  S #075604                        41
  CAS #1305-78-8
Lindane  S #009001                 3 & 45
  CAS #58-89-9
Linuron  S #035506                     30
  CAS #330-55-2
Linseed Oil  S #031603                 45
  CAS #8001-26-1
Magnesium phosphide  S #066504, 218100  34
  CAS #12057-74-8
Malathion  S #0577                     43
  CAS #121-75-5
Maleic hydrazide  S  #051501, 02,  03    13
  CAS #123-33-1
MAMA  S #013808                        45
  CAS #2321-53-1
Mancozeb  S #none                      41
  CAS #12001-34-2
Maneb  S #014505, 005050               41
  CAS #12427-38-2
MCPA  S #030501, 02? 030553, 56,  62;   34
         030563, 66; 030510, 11,  16,
  CAS #94-74-6
MCPB  S #019201                        44
  CAS #94-81-5
                                     Page

Metalaxyl (Ridomil®) S #113501         34
  CAS #57837-19-1
Methamidophos (Monitor®)  S #101201    34
  CAS #10265-92-6
Methanearsonates  S #013802, 03, 04,   13
                  05, 06, 07, 08
  CAS # for following corpounds
  calcium acid 5902-95-4
  MAMA 2321-53-1
  MSMA 2163-80-6
  DSMA 144-21-8
  octyl ammonium 6379-37-9
  docecyl ammonium 4410-88-2
Methazole  S #106001                   42
  CAS #20354-26-1
Methidathion  S #100301                34
  CAS #950-37-8
Methonyl  S #090301, 549400            34
  CAS #16752-77-5
Methoprene  S #105401, 549500          35
  CAS #40596-69-8
Methoxychlor  S #034001                43
  CAS #72-43-5
Methyl bromide  S #053201              40
  CAS #74-83-9
Methyl parathion  S #053501            38
  CAS #298-00-0
Metiram  S #014601                     41
  CAS #9006-42-2
Metolachlor  S #108801, 288700         35
  CAS #15972-60-8
Metribuzin  S #101101             26 & 39
  CAS #21087-64-9
Mevirphos  S #015801                   43
  CAS #7786-34-7
Mirex  S #039201                       10
  CAS #2385-85-5

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                                     Page
                                                                          Page
Molinate  S #041402                    42
  CAS #2212-67-1
Monitor*  see Methamidophos
Monocrotophos  S #058901          26 & 38
  CAS #6923-22-4
Monuron  S #035501                 8 & 35
  CAS #150-68-5
Monuron trichloroacetate S #035502     35
  CAS #150-68-5
MSMA  S #013803                        45
  CAS #2163-80-6
Muscalure  S #103201                   45
  CAS #27519-02-4
Nabam  S# 014503                       41
  CAS #142-59-6
Waled  s #034401               13,35 & 38
  CAS #300-76-5
Naprcpamide  S #103001                 43
  CAS #15299-99-1
Naptalam  S # 030701, 02, 03      27 & 39
  CAS #132-66-1
Napthalene  S #055801
  CAS #91-20-3
Napthaleneacetic acid
       03, 04, 07, 08,
  CAS #86-87-3
2-napthol  S #010301
  CAS #135-19-3
Neonycin sulfate  S #006313
  CAS #1405-10-3
Nicotine  S #056702
  CAS #54-11-5
Nicotine sulfate  S #056703
  CAS #65-30-5
Nitralin  S #037601
  CAS #4726-14-1
Nitrapyrin  S #069203
  CAS #1929-82-4
S #056001, 02,
055801, 589300
                35
35
                42
                27
                43
                43
                39
                41
Nitrofen  S #038201                    43
  CAS #1836-75-5
Norflurazon  S #105801            30 & 39
  CAS #27314-13-2
OBPA (10, 10' Oxybisphen
        oxarsine)  S #012601      14 & 35
  CAS #58-36-6
Qmadine-sodium  S #088004         27 & 41
  CAS #15922-78-8
OMPA  S #058601                         8
  CAS #152-16-9
Orthene®  see Acephate
Qryzalin  S #104201               27 & 39
  CAS #19044-88-3
Ovex  S #020201                        42
  CAS #80-33-1
Oxadiazon  S #109001                   42
  CAS #19666-30-9
Oxamyl  S #103801                      43
  CAS #23135-22-0
10,10 Oxybisphenoxarsine  see OBPA
Qxydeneton methyl  S #058702           43
  CAS #301-12-2
Oxyfluorfen  S #111601                 39
  CAS #42874-03-3
Oxythioquinox  S #054101               44
  CAS #2439-01-2
Paraquat  S #061612               14 & 43
  CAS #4685-14-7
Parathion  S #057501              27 & 38
  CAS #56-38-2
PCNB  S #056502                        22
  CAS #82-68-8
Pebulate  S #041403                    44
  CAS #1114-71-2
Pendimethalin  S #108501          30 & 39
  CAS #40487-42-1

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                                     Page

Pentachlorophenol  S #063001, 02,  4 & 29
                 03,08, 09, 10, 11
  CAS #87-86-5
  sodium pentachlorophenate #131-52-2
  potassium      "          #7778-73-6
Perfluidone  S #108001, 02             39
  CAS #37924-13-3
Permethrin  S #109701                  38
  CAS #52645-53-1
Perthane  S #032101                     8
  CAS #72-56-0
Phenarsazine chloride  S #063901        8
  CAS #578-94-9
Phenmedipham  S #098701                44
  CAS #13684-63-4
Phenothiazine  S #064501               45
  CAS #92-84-2
Phorate  S #057201                30 & 37
  CAS #298-02-2
Phosalone  S #097701                   35
  CAS #2310-17-0
Phosmet  S #059201                     42
  CAS #732-11-6
Phosphanidon  S #018201                38
  CAS #13171-21-6
Picloram  S #005101               30 & 42
  CAS #1918-02-1
Piperazine dihydrochloride  S #067401  45
  CAS #142-64-3
Piperonyl butoxide  S #067501     14 & 41
  CAS #51-03-6
Pirimicarb  S #106101                  43
  CAS #23103-98-2
Pirimiphos-ethyl  S #108101            43
  CAS #23505-41-1
Plantpin® (butoxicarboxim) S #113001   35
  CAS #39196-18-4
                                     Page

Potassium bifluoride  S #075203   30 & 41
  CAS #7789-29-9
Potassium bromide  S #013903           30
  CAS #7758-02-3
Potassium hydroxide  S #075602         27
  CAS #1310-58-3
Potassium iodate  S #075703       30 & 41
  CAS #7758-05-6
Potassium permanganate  S #068501 27 & 41
  CAS #7722-64-7
Profluralin  S #106601                 39
  CAS #26399-36-0
Prometon  S #080804                    45
  CAS #1610-18-0
Prometryn  S #080805                   43
  CAS #7287-19-6
Pronamide  S #101701              23 & 39
  CAS #23950-58-6
Propachlor  S #019101             30 & 39
  CAS #1918-16-7
Prcpanil  S #028201                    42
  CAS #709-98-8
Propargite  S #097601                  42
  CAS #2312-35-8
Propazine  S #080808                   42
  CAS #139-40-2
Propham  S #047601                     44
  CAS #122-42-9
Pyrazon  S #069601                     44
  CAS #1698-60-8
Ridomil®  see Metalaxyl
Ponnel  S #50301                        6
  CAS #299-84-3
Botenone  S #071003               14 & 43
  CAS #83-79-4
Byanodine  S #071502                   43
  CAS #15662-33-6

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                                     Page

Sabadilla alkaloids  S #002201         43
  CAS #8051-02-3
Safrole  S #097901                      8
  CAS #94-59-7-0
Simazine  S #080807               30 & 39
  CAS #122-34-9
Sodium arsenite  S #013603              8
  CAS #7784-46-5
Sodium bentazon  S #103901             39
  CAS #50723-80-3
Sodium bisulfate  S #073201            27
  CAS #7681-38-1
Sodium fluoroacetate/1080               4
   S #075003
  CAS #62-74-8
Sodium hydroxide  S #075603            27
  CAS #1310-73-2
Sodium polysulf ide  S #006902          44
  CAS #1344-08-7
Sodium TCA  S #081001                  44
  CAS #650-51-1
S,S,S,-tributyl phospho-
  rotrithioate (DEF)  S #074801        15
  CAS #78-48-8
Streptomycin  S #006306                44
  CAS #57-92-1
Strobane  S #020401                     8
  CAS #8001-50-1
Strychnine/strychnine sulfate           4
  S # 076901, 02
  CAS #57-24-9
  CAS #60-41-3
Sulfur  S #077501                      36
  CAS #7704-34-9
Sulfuryl Fluoride  S #078003           27
  CAS #2699-79-8
Sulprofos (Bolstar*) S #111501         36
  CAS #35400-43-2
                                     Page

Tabutrex  S #077802                    45
  CAS #141-03-7
Tar  S #022004                         27
  CAS #8007-45-2
TCBC  S #017304                        39
  CAS 1344-32-7
TCC  S #027901                         27
  CAS #101-20-2
Tebuthiuron  S #105501                 30
  CAS #34014-18-1
Temephos (Abate*) S #059001            36
  CAS #3383-96-8
1081  S #075002                        15
  CAS #640-19-7
TEPP  S #079601                        37
  CAS #107-49-3
Terbacil  S #012701                    36
  CAS #5902-51-2
Terbufos  S #105001                    37
  CAS #13071-79-9
Terbutryn  S #080813              15 & 42
  CAS #886-50-0
Terrazole*  S #084701                  36
  CAS #2592-15-9
Tetrachlorvirphos  S #083701           45
  CAS #961-11-5
Tetradifon  S #079202             22 & 38
  CAS #116-29-09
Tetrasul  S #079201                    42
  CAS #2227-13-6
Thicphanate ethyl  S #103401           27
  CAS #23564-06-9
Thicphanate methyl  S #102001     24 & 27
  CAS #23564-05-8
Thiram  S #079801                 30 & 40
  CAS #137-26-8
Toxaphene S #080501                    24
  CAS #8001-35-2

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                                     Page

TPTO S #83601                          30
  CAS #76-87-9
Treflan  S #036101                     41
  CAS #1582-09-8
Triadimefon  S #109901            29 & 40
  CAS #43121-43-3
Triallate  S #078802              15 & 42
  CAS #2303-17-5
S,S,S-Tributyl Phosphoro-
   trithioate (DBF)  S #074801         15
  CAS #78-48-8
Tributyl phosphorotri-
  thioite (Merphos)  S #074901         16
  CAS #130-50-5-8
Trichlopyr  S #116001,2                45
  CAS #'s 55355-06-3,-57213-69-1
Trichlorfon  S #057901         16,30 & 37
  CAS #52-68-6-2
2,4-5-Trichlorcphenol  S #064204, 10,   5
             11, 12, 14, 17, 19, 20
  CAS #95-95-4
Trifluralin  S #036101                 25
  CAS #1582-09-8
Trysben (Benzac)  S #017303             8
  CAS #50-12-7
2,4,5-T/Silvex  S #082501         10 & 25
  CAS #93-765, 93-72-1
Velpar®  see Hexazinone
Vendex  S #104601                      42
  CAS #13356-08-6
Vemolate  S #041404                   39
  CAS #1929-77-7
Vitavax®  see Carboxin
Warfarin  S #086002, 086003            36
  CAS #81-81-2
  sodium warfarin #129-06-6
  potassium warfarin #2610-86-8
Zinc phosphide  S #088601
  CAS #1314-84-7 & 51810-20-9
  CAS #12122-67-7
Zineb  S #014506
  CAS #142-14-3
Ziram  S #034805,6
  CAS #137-30-4
Page

  36


  41

  44

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