United StrtM
Environmental Protection
Agancy
Off ice of
Pwticide* and Toxic Subftanc
Washington DC 20460
June 1987
Pttticidtt
Guidance for the
Reregistration of
Pesticide Products
Containing Oxamyl
as the Active Ingredient
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GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
OXAMYL
SHAUGHNESSY No. 103801
AS THE ACTIVE INGREDIENT
CAS NO. 23135-22-0
EPA CASE NUMBER 108
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D.C. 20460
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TABLE OF CONTENTS
I. Introduction ....... 1
II. Chemical(s) Covered by this Standard . 4
A. Description of Chemical 4
B. Use Profile . ......._. 5
III. Agency Assessment . ........... 6
A. Summary . .„ 6
B. Preliminary Science Findings 8
C. Tolerance Reassessment .16
D. Tolerance Assessment System Reassessment. . . 17
IV. Regulatory Position and Rationale. ......... 19
A. Summary of Positions and Rationales 19
B. Criteria for Registration 25
C. Acceptable Ranges and Limits 26
D. Required Labeling 27
V. Products Subject to this Standard ......... 33
VI. Requirement for Submission of Generic Data 36
A. What are generic data?
B. Who must submit generic data?
C. What generic data must be submitted?
D. How to comply with DCI requirements
E. Procedures for requesting a change in protocol
F. Procedures for requesting extensions of time
G. Existing stocks provisions upon suspension or
cancellation
VII. Requirement for" Submission of Product-Specific Data. 41
VIII. Requirement for Submission of Revised Labeling ... 42
IX. Instructions for Submission 43
A. Manufacturing use products (sole active)
B. Manufacturing use products (multiple active)
C. End use products
D. Intrastate products
E. Addresses
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APPENDICES
I. DATA APPENDICES
Guide to Tables
Table A
Table B
Table C
II. LABELING APPENDICES
Summary of label requirements and table
40 CFR 162.10 Labeling Requirements
Physical/Chemical Hazards Labeling Statements
Storage Instructions
Pesticide Disposal Instructions
Container Disposal Instructions
III. USE INDEX APPENDIX
IV. BIBLIOGRAPHY APPENDICES
Guide to Bibliography
Bibliography
V. FORMS APPENDICES
EPA Form 8580-1 FIFRA }3(c)(2)(B) Summary Sheet
EPA Form 8580-6 Certification of Attempt to Enter into an
Agreement with Other Registrants for Development
of Data
EPA Form 8580- Product Specific Data Report (End-Use Products)
EPA Form 8580- Formulator's Exemption Statement
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I. INTRODUCTION
The Registration Standards Program
EPA has established the Registration Standards program in order to
provide an orderly mechanism by which pesticide products containing
the same active ingredient can be reviewed and standards set for
compliance with FIFRA. The standards are applicable to reregistration
and future applications for registration of products containing the
same active ingredient. Each registrant of a product containing an
active ingredient subject to this Standard who wishes to continue to
sell or distribute that product must bring his product and labeling
into compliance with FIFRA, as instructed by this Standard.
Pesticides have been grouped into use clusters and will be reviewed on
the basis of a ranking scheme giving higher priority to (1) pesticides
in clusters used on food and feed crops; and (2) pesticides produced
in large volumes.
The Registration Standards program involves a thorough review of the
scientific data base underlying a pesticide's registration. The
purpose of the Agency's review is to reassess the potential hazards
arising from the currently registered uses of the pesticide; to
determine the need for additional data on health and environmental
effects; and to determine whether the pesticide meets the "no
unreasonable adverse effects" criteria of FIFRA. In its review EPA
identifies:
1. Studies that are acceptable in fulfilling the data requirements
for the currently registered uses of the pesticide.
2. Additional studies necessary to support continued registration.
The additional studies may not have been required when the product was
initially registered or may be needed to replace studies that are now
considered inadequate.
3. Labeling revisions needed to ensure that the product*is not
misbranded and that the labeling is adequate to protect human health
and the environment.
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The detailed scientific review, which is not contained in this
document, but is available upon request , focuses on the pesticide
active ingredient. The scientific review primarily discusses the.
Agency's evaluation of and conclusions from available data in its
files pertaining to the pesticide active ingredient. However, durirj
the review of these data the Agency is also looking for potential
hazards that may be associated with the end use products that contain
the active ingredient. The Agency will apply the provisions of fiis
Registration Standard to end use products if necessary to protect
human health and the environment.
The Agency's reassessment results in the development its regulacory
position which is contained in Section IV of this Standard. Based on
this regulatory position, the Agency may prescribe a variety of steps
to be taken by registrants to maintain their registrations in
compliance with FIFRA. These steps may include:
1. Submission of data in support of product -registration;
2. Modification of product labels;
3. Modifications to the manufacturing process of the pesticide
to reduce the levels of impurities or contaminants;
4. Restriction of the use of the pesticide to certified
applicators or other specially trained individuals;
5. Modification of uses or formulation types; or
6. Specification of packaging limitations.
Failure to comply with these requirements may result in the issuance
of a Notice of Intent to Cancel or a Notice of Intent to Suspend (in
the case of failure to submit data).
The scientific reviews are available upon request from the
Information Services Sev- ion, Room 236, CM#2, 1921 Jefferson
Davis Highway, Arlington, VA. 22202 (Tel. (703) 557-4453). Ninety days
after the issuance of the Standard, the reviews may be purchased from
the National Technical Information Service, 5285 Port Royal Road,
Springfield, VA 22161.
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In addition, in cases in which hazards to human health or the
environment are identified, the Agency may initiate a special review
of the pesticide in accordance with 40 CFR Part 154 to examine in
depth the risks and benefits of use of the pesticide. If the Agency
determines that the risks of the pesticide's use outweigh its
benefits, the Agency may propose additional regulatory actions, such
as cancellation of uses which have been determined to cause
unreasonable adverse effects on the environment.
EPA has authority under the Data Call-In (DCI) provisions of FIFRA
sec. 3(c)(2)(B) to require that registrants submit data to answer
questions regarding the chemical, toxicological, and environmental
characteristics and fate of a pesticide. This Registration Standard
lists the data EPA believes are necessary to resolve concerns about
this pesticide. These data are listed in the Tables A, B, and C in
Appendix I. Failure to comply with the DCI requirements enumerated in
this Registration Standard may result in issuance by EPA of a Notice
of Intent to Suspend the affected product registrations.
Registrants are reminded that FIFRA sec. 6 (a)(2) requires ±hem to
submit factual information concerning possible unreasonable adverse
effects of a pesticide at any time that they become aware of such
information. Registrants should notify the Agency of any information,
including interim or preliminary results of studies, if those results
suggest possible adverse effects on man or the environment. This
requirement continues as long as the products are registered by the
Agency.
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II.CHEMICAL COVERED BY THIS STANDARD
A. DESCRIPTION OF CHEMICAL
Oxamyl is the American National Standards Institute (ANSI) approved
common name for a carbamate insecticide produced solely in the United
States by E.I. DuPont de Nemours.
The chemical name for oxamyl is Methyl N'N'-dimethy1-N-
[(methylcarbamoyl)oxy]-1-thiooxamimidate. Other common names and
trade names include DPX 1410, Vydate, and thioxamyl (International
Standardization Organization, ISO).
Empirical Formula: C7H13N303S
Molecular Weight: 219.3
CAS Registry No.: 23135-22-0
OPP Shaughnessy No.: 103801
CHEMICAL STRUCTURE
o
H'C\ II .N-0-C-NHCH,
N-C-CX
H// X
Oxamyl is a white, crystalline, solid with a melting point of 100-102
degrees centigrade. Oxamyl is soluble in water at 28g/100g, methanol
at 144g/100gr.' acetone at 67g/100g, ethanol at 33g/100g, and toluene at
Ig/lOOg.
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B. USE PROFILE
Type of Pesticide: Insecticide, nematocide, acaricide.
Pests Controlled: Insects, mites, nematodes.
Registered Uses: Oxamyl is registered on a variety of field
crops, vegetables, and ornamentals. Some
products are registered for greenhouse and
potted ornamentals.
Annual Usage: Estimated at 580,000 Ibs active ingredient.
Predominant Uses: Apples, potatoes, tomatoes.
Mode of Activity: Cholinesterase inhibitor. Systemic in plants.
Formulations: 42% formulation intermediate.
24%soluble concentrate (SC). 2 Ibs ai.per gal.
10% granular (G).
There is no technical oxamyl product registered.
Basic Registrant: E.I. DuPont de Nemours & Co. Inc.
Initial Registration: 1974
Number of Registrants: 4
Restrictions: The 24 SC product is classified as a Restricted
Use Pesticide. Oxamyl is not allowed for
outdoor application in Suffolk and Nassau
counties, New York, as a result of groundwater
contamination.
End-Use Registrations
Formulation Section 3^ Section 24C
Granular 5 2
Soluble Concentrate 1 69
The following states have 24(C) registrations for oxamyl, the number
per state is included in parentheses(): AZ(3), CA(8), C0(l), CT(2),
DE(1), FL(6), HI(4), ID(1), IL(1), IN(1), MA(1), MD(2), MI(6), NC(1),
ND(1), NJ(1), NM(1), NY(4), OH(2), OR(4), PA(4) , PR(2), SC(1), TX(4),
VA(3), VT(2), WA(3), WV(1).
There are no intrastate products for oxamyl and no multiple active
ingredient products.
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III. AGENCY ASSESSMENT
A. SUMMARY SCIENCE STATEMENT
The Agency has reviewed oxamyl data in the areas of acute toxicity,
subchronic and chronic toxicity, oncogenicity, reproductive effects,
mutagenicity, plant and animal metabolism, residues, environmental
fate and exposure, and ecological effects. As a result of this
review, the Agency has determined that certain changes in the|
conditions of registration, including specific label restrictions and
submission of missing data, are necessary to maintain current
registrations of products and support registration of new products
containing oxamyl. A summary of these data gaps and label revisions
appears in Table 1. Note that this list contains only summary
information on data gaps. More detailed information can be obtained
by referring to Table A in Appendix 1. Based upon a review of the
available data the Agency has reached the following interim
conclusions. A detailed discussion of the Agency's science findings
can be found in section III.B entitled "Preliminary Science Findings".
1. Oxamyl is highly toxic via the oral and inhalation routes of
exposure. The manufacturing use product has classified as
Toxicity Category I.
2. While the available data are insufficient to permit a complete
evaluation of the chronic effects from oxamyl exposure, no oncogenic
response was noted in a valid mouse oncogenicity study. Based upon
that study, the NOEL for chronic toxicity is 25 ppm and the LOEL is 50
ppm. No structural abnormalities were reported in a rabbit teratology
study. The developmental NOEL was 4 mg/kg/day (HOT) and the maternal
NOEL is 1 mg/kg/day.
3. Oxamyl is highly toxic to birds, bees and mammals, and moderately
toxic to fish. Technical oxamyl is moderately toxic to freshwater
invertebrates. However, the 24SC formulation is highly toxic to some
freshwater ./invertebrates. Uses of oxamyl may threaten endangered
species.
4. Leaching studies indicate that unaged (parent compound) oxamyl may
leach in certain soil types. Oxamyl has been found in- minute
quantities in a small percentage of drinking water wells in Suffolk
County, New York and in Massachusetts. Occupational illnesses h < e
been reported in California following exposure to spray dri.:t.
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TABLE 1.
SUMMARY OF DATA GAPS AND REQUIRED LABELING FOR OXAMYL
Toxicology
Acute Dermal Toxicity
Primary Eye Irritation
Primary Skin Irritation
Dermal Sensitization
21 Day Subchronic Dermal Toxicity
Chronic Toxicity (rodent & non-rodent;
Oncogenicity (rat)
Teratogenicity (rat)
Reproduction
Gene Mutation
Chromosomal Aberration
General Metabolism
'50
Ecological Effects
Avian Dietary LC5g (upland & waterfowl;
Field studies (avian & mammalian)
Estuarine and Marine Fish LCC
Fish Early Life Stage
Honeybee Toxicity of Residues on Foliage
Environmental Fate
Hydrolysis
Photodegradation in Water
Anaerobic Soil Metabolism
Leaching and Adsorption/Desorption
Soil Dissipation
Rotational Crops (confined)
Glove Permeability
Droplet Size/Drift Evaluation
Product Chemistry
Description of Manufacturing Process
Discussion of Formulation and Impurities
Preliminary Analysis of Product Samples
Certification of Ingredient Limits
Analytical Methods to Verify Certified Limits
Physical and Chemical Characteristics
Residue Chemistry
Storage Stability
Plant Residues
Labeling Revisions
Animal Metabolism, Ruminant and Poultry
Processing Studies
protective Clothing
~_'oundwater Advisory Statement
Fish and Wildlife Toxicity Warnings
Reentry Restrictions
Restricted Use Classification (granular)
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B. PRELIMINARY SCIENCE FINDINGS
1oAcute Toxicity
Oxamyl is extremely toxic to mammals and is classified in Toxicity
Category I for the oral and inhalation routes of exposure. Oxamyl
acts by inhibition of cholinesterase. Toxic signs result fron
excessive stimulation at cholinergic junctions in the autonomic and
central nervous systems, and include tremors, fascicu1 ation,
salivation, labored respirat _ :>n, diarrhea, and exophthalmos. Atropine
has been shown to be an antidote in both rats and monkeys. Studies on
a technical grade product indicate that the acute oral LDcQ for male
rats is 3.1 mg/kg; female rats, 2.5 mg/kg. Acute dermal toxicity
studies with a technical grade formulation were considered
supplementary because of incomplete reporting. An additional dermal
toxicity study is required. The acute inhalation LCcg for a 1 hour
exposure is 0.17 mg/L for the male rat and 0.12 mg/L for the female.
With a 4 hour exposure the acute LC5Q for male rats is 0.064 mg/L.
Limited data available indicate that oxamyl produces some reversible
eye irritation. These data are supplementary and an additional study
is required. Dermal irritation data reviewed indicate that oxamyl
caused severe systemic effects (cholinesterase inhibition) and some
dermal irritation. The study is supplementary and an additional study
is required. The limited data do not indicate dermal sens itization
from oxamyl but the study is supplementary and an additional -study is
required.
2.Subchronic toxicity
The available data include a a 90 day rat oral study which is
considered invalid and a 13 week dog oral study which is considered
supplementary. Additional studies are usually required in both rodent
and non-rodent species. However, subchronic oral toxicity data are
superseded by the requirement for chronic studies in rats, dogs, and
mice. No subchronic dermal 21 day study is available for oxamyl and a
study is required. No 90 day subchronic dermal or subchronic
inhalation study are available. These studies are not required for
the presently registered use patterns. As Oxamyl is not an
organophosphate, no subchronic neurotoxicity study is required.
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3.Chronic Toxicity
Chronic feeding studies in the rat and the dog have been reviewed and
found to be inadequate. In the rat study, 30 rats/sex/dose were fed
diets containing 50, 100, and 150 ppm oxamyl for 2 years. At the two
highest doses decreases in body weights of both male and female rats
were observed. No significant histopathological changes were noted in
the treated animals. The NOEL for chronic toxicity.in rats was 50 ppm
and the LOEL was 100 ppm. This rat study is classified as
supplementary because of missing histopathology data and insufficient
clinical chemistry. While no adverse effects were observed in the dog
study, it too is classified as supplementary due to the lack of
histopathology on interim sacrificed animals, insufficient numbers of
animals in the control and high dose groups, and because the highest
dose tested did not approach the maximum tolerated dose.
4. Oncogenicity
In an acceptable study, mice orally dosed at 25, 50, and 75 ppm oxamyl
for 2 years displayed decreased body weights at the higher two doses,
but no other histopathological changes. Relative to the controls, no
increase in tumor incidence was found in the treated groups. Based
upon the mouse oncogenicity study, the NOEL for chronic toxicity in
mice is 25 ppm; and the LOEL is 50 ppm. The rat study also showed no
increase in tumor incidence but was found to be unacceptable and must
be repeated.
5.Developmental and Reproductive Effects
The available teratology data only partially satisfy the data
requirements. In an acceptable rabbit study, oxamyl was administered
orally at doses of 1, 2, and 4 mg/kg/day- No developmental effects
were observed at any dose level and the only observed change was
decrease in body weight of the 2 and 4 mg/kg/day groups. This study
yielded a developmental NOEL of 4 mg/kg/day (HOT) , and a maternal NOEL
of 1 mg/kg/day. In a second study female rats were fed oxamyl at
dietary concentrations of 50, 100, 150, and 300 ppm from day 6 through
day 15 of the gestation period. While no functional or structural
abnormalities were reported, the study contains only summary data and
is therefore classified as supplementary. An additional teratology
study with rats is required. In a 3 generation rodent reproduction
and fertility study ^he only observed effect was a decrease in
weights of in the wee nings at mid and high doses. Study deficiencies
include; an insufficient number of litters, no report of the number of
animals, and insufficient reporting of data. The study is classified
as supplementary and another study is required.
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6. Mutagenicity
An acceptable differential toxicity assay using B._ subtilis indicates
that oxamyl did not cause DNA damage. No chromosomal aberration assays
have been submitted, and an acceptable study is required. An Ames
assay using S_._ tYphj.mi.rJ.um and £_._ co]^ showed that oxamyl did not
cause gene muta"tlon. Similar results were obtained in a host-mediated
assay using §_._ ty_phi.mi.r_ium. However, the Ames assays lack
confirmation by another independent study and the toxicity of oxamyl
was not evaluated for dose selection. For the host-mediated study,
certain crucial information concerning clinical signs in the treated
mice and the data on the preliminary dose selection study are missing.
An acceptable study is required.
7. Metabolism
The two available metabolism studies do not fulfill Agency
requirements. One study used only two male rats. The other study used
rat liver homogenate. Both studies are classified as supplementary.
Additional studies are required.
8. Environmental Fate and Ground Water
The available data are insufficient to fully assess the environmental
fate of oxamyl, including the extent of groundwater -contamination, and
its persistence in the environment. Oxamyl has been found in
drinking-water wells in Suffolk County, New York, and in Massachusetts
at levels from 1 to 395 ppb. In 1983, the New York State Health
Department limit for oxamyl was 50 ppb. In 1985, Massachusetts also
considered 50 ppb as a guideline limit for oxamyl. In'New York, less
than 0.1% of the samples tested during the 5 year period from 1980
thru 1985 exceeded 50 ppb. Oxamyl residues were detected below 50 ppb
in 2.9% of the total samples tested (15,535) at an average
concentration of 10 ppb and a median concentration of 3 ppb. In
Massachusetts, of the 146 samples tested in 1985, only 1 positive
sample at 1 ppb was found.
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In the available hydrolysis study, data to support the claimed
quantitative conversion of oxamyl to oxime were not provided and the
purity of the test substance was not specified. Acceptable data from
this study must be provided or an additional study is required. The
available data for photodegradation in water are not acceptable. This
report contains two experiments. In the first, the test substance was
not characterized and the recovery rate was not supported by data. In
the second, the test solutions were not sterile, the test substance
was not characterized, the solutions were not buffered, the
temperature was not reported, sunlight parameters were not described
and there was no material balance. Data to support the reported 98%
recovery, purity and specific activity of the test substance must be
supplied, or an acceptable study is required. The one study available
concerning photodegradation in soil only partially fulfills data
requirements because of test substance purity and because degradates
were not characterized. Additional data are not required, however,
because most oxamyl soil applications involve soil incorporation.
Available data adequately describe the metabolism of oxamyl in aerobic
soil. Labeled oxamyl at 4 and 20 ppm degraded with a half-life of 14-
28 days in silt loam soil incubated at 25 degrees C and 70% water
holding capacity. The major degradate was carbon dioxide. Other
degradates included the oxime and N,N-dimethyloxamic acid. Neither of
the two studies evaluating anaerobic soil metabolism fulfill Agency
requirements. In the first study the test substance purity was not
given, the oxamyl was not aged prior to introduction of anaerobic
conditions,, soils were not completely characterized, and fncubation
temperatures were not reported. In the second study the test
substance was uncharacterized, the treated soil was not initially aged
aerobically, incubation temperatures were not reported, degradates
were not adequately identified, and the analytical methodology was not
properly described. Acceptable data are required.
Three studies relative to leaching and adsorption/desorption were
reviewed. The sum of these data are sufficient to demonstrate the
leaching potential of unaged oxamyl. Unaged oxamyl (parent compound)
is very mobile in sandy loam and silt loam soil columns (Average TLC
Rf values were 1.00 and 0.70, respectively). Additional data are
required for, aged oxamyl residues employing a column leaching study
which includes adequate identification of residues.
Two terrestrial field dissipation studies were reviewed. The first
does not fulfill the data requirement because the maximum application
rate wrs not used, the field test data were incomplete (including
confirmation of the application rate), and "he test substance was not
adequately characterized. In the second st iuy the maximum application
rate was not used, the purity of the test substance was not reported,
soils were not completely characterized, and the patterns of formation
and decline of degradates were not addressed. Complete studies are
required. The requirement for a long-term soil dissipation study is
deferred until the receipt of acceptable field dissipation data.
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Data for confined accumulation on rotational crops could not be
validated as the application rate was not confirmed by immediate
posttreatment sampling. In addition, the test material was
uncharacterized, soil samples were not analyzed at the time of harvest
of the rotational crops, residues other than oxamyl and oxime were
not identified, and other deficiencies were noted. Complete data are
required. Data for field accumulation are deferred until such time as
acceptable confined rotational studies have been received and
reviewed.
Data for foliar dissipation, dermal exposure, and inhalation exposure
were submitted and have been reviewed. Additional information is
needed for conversion of the reported data to surface residue levels.
Soil dissipation studies are not available and will be required for
those use patterns where workers will be exposed directly to
substantial quantities of soil during their work such as in the
harvesting of potatoes, carrots, or celery.
A well-water monitoring study has been reviewed and found to be
valid. Oxamyl was detected at 5.0 to 5.4 ppb in July in three newly
drilled wells (8.8 to 12.2 ft.) located within 10 feet (in the
direction of ground water flow) of a potato field on Long Island, NY,
that had been treated with oxamyl(purity unspecified) at yearly
application rates of 6 and 9 Ib. ai/acre that spring and the previous
year. Subsequent sampling in August and December showed no detectable
(<5 ppb) oxamyl. Eight other wells on Long Island, 30 to 400 ft. "from
potato fields treated with oxamyl at yearly rates ranging from 3 to 11
Ib ai/acre that spring and the previous year were sampled several
times and no oxamyl residues were detected.
A freezer storage stability study could not be validated as the method
of analysis was not reported. The method should be submitted.
9. Ecological Effects
Available data adequately describe the acute oral toxicity of oxamyl
to birds (See Table 2, below). Technical grade 97.1% oxamyl is highly
toxic to birds. The acute oral toxicity of a 24% SC formulated
product also indicates a high toxicity to birds although there is no
guidelines requirement for avian toxicity data on formulated products.
Residues of the SC formulation on crops used by birds are likely to be
above the bobwhite LC50 and lowest reproductive effect level for
waterfowl. For the granular formulat; c i, assuming a size of 2 mg per
granule (0.2 mg ai) , one granule is approximately equivalent to the
LD50 of a 67 g bird or small mammal. Available studies on avian
dietary toxicity for the technical have been evaluated and found to be
inadequate. Additional studies on both upland game birds and
waterfowl are necessary.
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Table 2. The Acute Oral Toxicity of Oxamyl to Avian Species
Species Percent A.I. LD50, mg/kg
Mallard 97.1 3.16
Mallard 24 10.75
Bobwhite 24 39.20
Avian reproduction studies for upland game birds and waterfowl have
been reviewed and found to be acceptable. For the bobwhite, the NOEL
is 50 ppm (highest dose tested). For the mallard the NOEL is 10 ppm
and the LOEL is 50 ppm (highest dose tested).
Data from simulated or actual terrestrial field tests are required for
formulated products of oxamyl because EEC's exceed the avian LD50 and
LC50 and mammalian LD50 levels as determined in laboratory tests.
These data are required for foliar applications of 24% soluble
concentrate products and soil applications of 10% granular products.
Available data are sufficient to satisfy guidelines requirements for
acute toxicity tests with the technical grade product for both
coldwater and warmwater species of freshwater fish (See Table 3).
These data indicate that technical oxamyl is moderately toxic to
fish. Additional data on a 24% formulated product indicate moderate
toxicity to warmwater fish and slight toxicity to coldwater fish.
Table 3. Acute Toxicity of Oxamyl to Freshwater Fish
Species Percent A.I. LC50, ppm
Bluegill 90 5.6
Rainbow Trout 90 4.2
Bluegill 24.8 6.1
Rainbow Trout 24 12.4
Studies utilizing Da^p_hrii.a inagjna indicate that technical oxamylis
moderately toxic to freshwater invertebrates (LC50 5.7 ppm). No
additional data for the technical are required. The 24 SC formulation
is highly toxic to freshwater invertebrates, and with an LC50 for D_._
magna of 1.95 ppm, is more toxic than the technical. As current
registered uses of oxamyl do not include direct application to water
and do not .result in EEC's greater than the freshwater invertebrate
LC5Q, freshwater invertebrate testing with formulated products ar*> not
required.
The data evaluating the toxicity of technical oxamyl to estuarine and
marine fish have been reviewed and found to be unacceptable. A 96
hour LC50 study for a fish, preferably Menidia sp. or spot, Leiostomus
xanthurus must be submitted.
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While no data evaluating the effects of technical oxamyl to marine
invertebrates were available, acceptable data on the 24% formulated
product have been reviewed and found to be sufficient to fulfill the
shrimp and oyster estuarine and marine organism requirements. The
ECSOs for grass shrimp and eastern oysters are 0.7 and 0.1 ppm ai,
respectively. Available studies on fish early life stages have been
reviewed and found to be unacceptable. As the aquatic EEC's from all
foliar uses of oxamyl at 2.0 Ibs ai/acre and higher, from 24% SC soil
applications without incorporation, and from 10% granular treatments
on peanuts and ornamentals all exceed 0.01 the LC5Q for rainbow trout,
fish early life stage testing is required.
Aquatic invertebrate life cycle data evaluating the effects of
technical oxamyl on Daphnia magna have been reviewed and found to
satisfy the invertebrate life cycle requirements. No effects were
observed at the highest test concentration of 1 ppm.
Data from honey bee acute contact LD50 studies are sufficient to
satisfy this guideline requirement. This information indicates that
oxamyl is, moderate to high in toxicity to honey bees. For this
reason, data from a honey bee residual foliage toxicity test is
required and must be submitted.
10. Endangered Species
The Agency has evaluated the risk oxamyl poses to endangered species,
based on jeopardy opinions prepared by the Department of Interior's
Office of Endangered Species (OES) regarding oxamyl's use on certain
crops. This analysis indicates that the use of oxamyl on certain
crops may jeopardize certain endangered species. The Agency has
developed endangered species labeling statements which govern the use
of oxamyl in areas inhabited by endangered species. This labeling has
been required through PR Notices 87-4 and 87-5 issued May 1, 1987.
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11. Data Call-in Notices Issued
The Agency has issued the following 3(c)(2)(B) Data Call-in Notices:.
Date Issued Data Required Status
05/31/84
05/27/86
Environmental Fate
Hydrolysis
Photodegradati on-water
Photodegradati on-soi1
Aerobic soil
Anaerobic soil
Mobi1i ty
Field Dissipation-soil
Product Chemistry
Water Solubility
Vapor Pressure
Octanol water partition
Foliar Dissipation
Soil Dissipation
Dermal Exposure
Inhalation Exposure
Submitted Existing Data. An
Agency review of the data
indicated certain notable
deficiencies. Registrant
submitted additional
information 03/04/87, and
04/01/87 which was reviewed
for this standard.
coefficient
Registrant response
reviewed for this.
standard.
12. Reported Pesticide Incidents
A search of the files in the Pesticide Incident Monitoring System
(PIMS) reveals four incidents reported to the Agency between 1966 and
1979 when PIMS was active. All incidents involved human exposure to
oxamyl alone in agricultural situations. The circumstances were
described as container failure, improper storage, ingestion, and
improper disposal. A fatality was reported in one incident involving
probable container failure (accident undescribed). The other three
incidents resulted in hospitalizations.
v
California, data for the period 1981 through 1985 list the following
occupational illness for oxamyl; systemic (13), eye (3), skin (1).
Most exposures apparently involved spray drift. Four incidents
occurred during ground application and two during mixer-loader
operations.
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C.TOLERANCE REASSESSMENT
Tolerances have been established for oxamyl in or on a number of raw
agricultural commodities at levels between 0.1 and 10.0 ppm. A
listing of the established tolerances is located at the end of this
section. There are no Mexican tolerances for the sites registered for
use in the United States.
After evaluation of the available residue and toxicology studies
supporting these tolerances, the following conclusions have been
reached:
Residue Data
1. Data gaps exist for storage stability. Upon receipt of the
required storage stability data, conclusions regarding the adequacy of
established tolerances may change. No tolerances are presently
established for residues in or on animal commodities. An evaluation
of required data for animal metabolism and residues in feed items may
indicate the necessity for studies and tolerances pertaining to
residues in animal commodities.
2. Sufficient data are available to ascertain the adequacy of the
established tolerances (40CFR 180.303) for residues of oxamyl in or on
sweet potato,' soybeans, soybean straw, eggplants, peppers, tomatoes,
cucumber, honeydew melon, watermelon, summer Bnd winter squash,
cantaloupes, apples, pears, peppermint and spearmint hay, peanuts,
peanut hulls, pineapples, and pineapple bran.
3. Insufficient data are available to ascertain the adequacy of the
established tolerances (40CFR 180.303 and 21 CFR 561.285) for residues
of oxamyl in or on carrots, ginger, potatoes, garlic, onions, celery,
bananas, cottonseed, peanut forage and hay, pineapple forage, and
citrus.
4. Processing studies are required for the following commodities:
citrus, potatoes, soybeans, tomatoes, cottonseed, pineapple, and
peanuts.
5. Upon receipt of the required residue data, the commodity entry
"Root crop vegetables" will be deleted and appropriate individual crop
(carrots, ginger, potatoes, sweet potatoes, garlic, onions) or crop
group (Root and Tuber Vegetables Group and Bulb Vegetables Group)
tolerances will be established.
6. Data are required to determine whether tolerances are needed to
support registered uses of oxamyl on nonbearing cherries, peaches,
plums, and strawberries.
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7. As there are no registered uses of oxamyl on pumpkins, a
registrant must propose a use or the tolerance will be revoked. This
use must be identical to the registered use on winter squash (winter
squash data are used to support the 2 ppm- pumpkin tolerance).
Otherwise the proposed use on pumpkins must be accompanied by
appropriate residue data to assess the adequacy of the established
tolerances.
8. Data are required to determine the exposure of man to residues of
oxamyl resulting from its use on tobacco.
Toxicology Data and Acceptable Daily Intake
An ADI had been determined by the Agency Reference Dose (RFD)
committee based upon a 2 year rat feeding study. Compound related
"effects were decreases in body weights in both mid and high dose rats
of both sexes. The NOEL in this study was 50 ppm (2.5 mg/kg) .
Utilizing an uncertainty factor of 100, the ADI was set at 0.025
mg/kg/day.
Based upon a reevaluation of the data base, the 2-year rat feeding
study is now classified supplementary. Nevertheless, because the sum
of the available data indicate no increase in tumors, and there are no
information to suggest that the ADI is inadequate to protect human
health, a provisional ADI (PADI) will continue to be based upon this
study with the same uncertainty factor until acceptable studies have
been submitted and all data gaps have been filled.
Tolerance Assessment System Tolerance Reassessment
1. The provisional acceptable daily intake (PADI) for this chemical
is 0.025 mg/kg/day.
2. The food uses evaluated by the Tolerance Assessment System (TAS)
were published tolerances as established under 40 CFR 180.303, and
pending tolerances that are under consideration by the Agency.
3. A comparison of published tolerances to the PADI was conducted
using the TAS Routine Chronic Analysis. This analysis calculates a
Theoretical ,M.aximum Residue Contribution (TMRC) based upon published
and pending' tolerances. The TAS analysis estimates dietary exposures
for the U.S. population average and for each of 22 subgroups. The
TMRC for the U.S. population average is 0.0132 mg/kg/day, which
occupies 53.1% of the PADI. The TMRCs for non-nursing infants and
children 1-6 years of age exceeded the PADI: 0.0387 mg/kg/day (155% of
the PADI) and 0.0334 (135% of the PADI), respectively.
For children 1-6 years old and non-nursing infants, the majority of
the TMRC was contributed by oranges and apples, which accounted for
70-80% of the estimated exposure. Since the TMRC is calculated, on the
basis of tolerance-level residues, it is likely that data reflecting
actual residue concentrations in these commodities would result in a
lower estimate of dietary exposure.
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Summary of Current Oxamyl Tolerances
Tolerances (ppm) (MRL)
Commodity United Statesa/ Canadab/' International iloaexk/
Carrots 0.1 — 0.1
Ginger 0.1
Potatoes 0.1 0.1 0.1
Sweet Potato 0.1 --- 0.1
Garlic 0.1
Onion 0.1 --- 0.05
Celery 3.0 --- 3.0
Soybeans 0.2 --- 0.1
Soybean Straw 0.2 — —
Eggplant 2.0 — —
Peppers (Bell ) 3.0 --- 3.0
Tomatoes 2.0 --- 2.0
Cantaloupe 2.0 --- 2.0
Cucumbers 2.0 --- 0.5
Honeydew melon 2.0 — 2.0
Pumpkinsd/ 2.0 — —
Summer Squash 2.0 — 2.0
Watermelon 2.0 --- 2.0
Winter Squash 2.0 — —
Citrus fruit group 3.0 — 3.0
Apples 2.0 --- 2.0
Pears 2.0
Bananas 0.3 — 0.2
Cottonseed 0.2 --- 0.2
Peppermint hay 10.0 — —
Spearmint hay 10.0 — —
Peanuts 0.2 --- O.le/
Peanut hay A forage 2.0 --- 2.0
Pineapples 1.0 — 1.0
Pineapple forage 10.0 --- ---
Pineapple branf/ 6.0 —• —
a/ The U.S. tolerance definition does not include theoximeeven
though the U.S. tolerance level is based upon combined levels of
oxamyl and its oxime combined.
b/ The Canadian tolerances are expressed in terms of oxamyl per se.
c/ The Codex Maximum Residue Levels are expressed as residues~~of~~oxamyl
and its oxime, expressed as oxamyl.
d/ Although this crop has a tolerance there are no EPA registered uses.
e/ Available U.S. data indicate that residues of oxamyl and its oxime
in or n peanuts will not exceed 0.1 ppm.
f/ Feed Additive Tolerance (21 CFR 561.285)
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IV. REGULATORY POSITION AND RATIONALE
A. SUMMARY OF REGULATORY POSITIONS AND RATIONALES
1. Special Review
The Agency is not placing oxamyl into Special Review at this time.
Rationale;
Calculations and models based upon the acute toxicity of oxamyl
indicate that granular formulations of oxamyl have the potential to
cause effects (i.e. non-target mortality) in birds and mammals, and
certain uses may exceed special review criteria. There is, however,
'only limited field data to support the finding that significant
adverse effects exist for terrestrial wildlife. The Agency is
requiring extensive field monitoring data to define the extent of
exposure and hazard. Evaluation of the necessity for a special review
on oxamyl will be completed after acceptable data have been received
and reviewed.
Incident data and human toxicity data on file indicate that systemic
poisoning to users and/or field workers can result from exposure to
oxamyl. Through the continued Restricted Use Classification of SC
formulations, and the imposition of protective clothing and equipment,
work safety and reentry statements, on all end-use product labels the
Agency believes that hazards posed by acute toxicity will be mitigated.
2. Restricted Use Classification
All oxamyl end-use products are candidates for restricted use
classification based upon toxicity to avian and mammalian species. In
addition, the Agency will continue to restrict the 24% SC formulation
of oxamyl on the basis of acute toxicity. Registrants of 10G products
have the option of either submitting the acute toxicity data described
in Table C or also classifying these products for restricted use on
the basis of acute toxicity. (Note: Submitted data may indicate
continued restricted use classification).
Rationale:
All registered oxamyl products bear outdoor uses that may pose risks
to non-target birds and mammals. All products are classified for
Restricted Use because residues per square foot occurring immediately
after application in or on the food of avian and mammalian species
exceed 1/10 the dietary LD50.
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Available data indicate that the 24% SC formulation should continue to
be restricted. These data indicate that the technical product is
extremely toxic via the oral and inhalation routes of administration.
These data are sufficient to indicate that the 24% SC formulation will
meet or exceed the acute toxicity criteria for restricted use
classification. Extrapolation of the existing data base to the 10G
formulation also indicates that these formulations are likely to
exceed the criteria for restricted use classification. However, due
to the nature of granular formulations, it is possible that certain
products will not exceed the criteria for restricted use
classification. Registrants are therefore being given the opportunity
to develop and submit acute toxicity data that will permit
determination of the appropriate toxicity categories and restricted
use wording for 10G products. Registrants may choose not to submit
these data and additionally classify these products for restricted use
on the basis of acute toxicity.
3.Endangered Species
Endangered species labeling has been required through PR Notices 87-4
and 87-5 issued May 1, 1987.
Rationale:
Oxamyl is toxic to certain species of .fish, birds, mammals, and
aquatic invertebrates which reside in areas where oxamyl is likely to
be used. The Agency, in an attempt to limit use of oxamyl in areas
where its use may be detrimental to endangered species, has required
through Pesticide Registration (PR) Notices endangered species
information on labeling of end-use products which contain uses for
certain crops. The required labeling is based on Biological Opinions
by the Office of Endangered Species (OES) of the Fish and Wildlife
Service, U.S. Department of the Interior.
4. Reentry Interval
An interim 48 hour reentry interval is being imposed for all
agricultural and greenhouse uses of oxamyl until such time as the
appropriate reentry data have been submitted and evaluated.
Rationale:
Oxamyl use patterns meet or exce^' those criteria in Section 158.40 of
40 CFR concerning the require:.ant for a reentry interval. Oxamyl
meets these criteria in that:
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1. The acute dermal toxicity of the technical grade is less than 200
rag/kg.
2. The acute oral toxicity of the technical grade is less than 50
rag/kg.
3. The Agency has received epidemiological evidence that residues of
this pesticide can cause adverse effects to individuals entering
treated sites. There have been a number of poisoning incidents with
oxamyl.
Oxamyl also meets the exposure criteria of 40 CFR 158.140 in that it
is registered for use on crops for which currer.- agricultural
practices include human tasks which involve substantial exposure to
residues of the pesticide. A 48 hour reentry interval is imposed
because of the high acute toxicity of oxamyl and data gaps regarding
post-application exposure.
5. Drift Studies Required
The Agency is requiring the submission of drift studies for 24 SC
formulations.
Rationale:
Because of reported occupational illness due to exposure to oxamyl as
a result of spray drift, droplet size spectrum and drift field
evaluation studies are required.
6. Groundwater Contamination and Advisory Statements
The Agency is requiring the addition of a groundwater advisory
statement to all oxamyl labels.
Rationale:
Oxamyl leaches through the soil and has been found in ground water.
At this time, because of the wide natural variability in soil types,
weather patterns and aquifer characteristics, it is impossible to
specify those circumstances when oxamyl will reach groundwater. The
ground water data call-in of 5/31/84 was initiated to derive that
information which will allow more accurate predictions concerning the
potential of oxamyl to contaminate ground water. These data have been
submitted and reviewed, but found to be inadequate and additional
information is required in this standard. Acceptable well-monitoring
studies do not indicate toxicological concerns from tip levels of
contamination reported at this time. Oxamyl residues will oe monitored
in the National Survey for Pesticides in Ground Water. EPA Method 531,
which measures both the parent and the oxime degradate, will be used.
A pilot program for all the selected pesticides has begun. Until the
leaching studies and the data from the pilot program have been
received and reviewed, a Groundwater Advisory Statement is required on
all oxamyl labels.
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Rotation Restrictions Expanded
A 6 month rotational interval for crops (including root crops) for
which no tolerance has been established, must appear on all oxamyl
labels.
Rationale:
Residues detected at 120 days in the confined crop rotation studies
indicate that the existing rotational crop interval of 4 months is
inadequate. Extrapolation of these levels indicate that a 6 month
interval will be adequate.
8. Glove Permeability Test Required
The Agency is requiring a glove permeability test for the soluble
concentrate formulation of oxamyl.
Rationale:
Gloves can greatly reduce dermal exposure and are required for
handling oxamyl SC products. However, there are no data demonstrating
which materials adequately limit dermal exposure. The Agency is
requiring a glove permeability study in order to determine which
materials are best suited for this use.
9. Restrictions on Flaggers for Aerial Application
The Agency is prohibiting the use of human flaggers during aerial
application, unless they are in an enclosed vehicle such as a pickup
truck or a tractor with a completely enclosed cab.
Rationale:
The Agency is imposing this requirement to minimize hazards to human
flaggers who inherently" face a risk of exposure by direct contact or
drift during.aerial application.
10. Changes in Precautionary Labeling
The Agency will require that end-use products bear updated
precautionary labeling (including protective clothi." and equipment)
related to the toxicity category to which each prc iuct is assigned.
For the 24SC formulation, these statements (Toxicity Category I) are
required through this registration standard. For the 10G formulation,
the Agency will determine the appropriate labeling after review- of the
required toxicology data for end-use products.
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Rationale:
Because of the acute toxicity of oxamyl products, specific
precautionary statements are required to prevent poisoning of workers
or applicators by direct exposure or contact with contaminated
clothing or materials. Extrapolation of data from the technical is
sufficient to determine the appropriate precautionary labeling for the
24 SC product. Registrants of 10 G products have the option of either
utilizing Toxicity Category I precautionary labeling and the
protective clothing and equipment statements described under
P.L ?§2Hi£^^ L^k®.Lill2 in this standard or making the appropriate
revisions after the submission of the required product specific acute
toxicology data.
11 .New Tolerances
No significant new tolerances or significant new food uses will be
granted until the Agency has received data sufficient to evaluate the
dietary exposure to oxamyl.
Rationale:
Residue chemistry and toxicology data are insufficient to assess the
adequacy of existing tolerances. Animal metabolism, field residue,
processing and storage stability data are required. Pertinent
toxicology data gaps include chronic toxicity, oncogen ic i ty ,
teratogenicity, reproduction, and mutagenicity. Refer to Appendix I,
Table A for specific residue chemistry and toxicology data required.
A tolerance reassessment cannot be completed until these data are
submitted .
12. Labcj^njj for Ha_za_rd_s to Non-target Organisms
Revised labeling for hazards to non-target organisms are required.
Rationale:
Data indicate that oxamyl is highly toxic to birds and mammals and
moderately toxic to aquatic organisms. Other data indicate that
oxamyl is moderately to highly toxic to the honeybee. Precautionary
label statements relative to the potential exposure of non-target
organisms to oxamyl will provide use information to promote practices
to limit such non-target exposure.
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13. Use Directions Nursery and Ornamental Plants
Use directions for nursery and ornamental plants must be revised to
prohibit applications of oxamyl in domestic situations (such as to
potted plants or interior plantscapes in or around homes, shopping
malls, or commercial buildings). This statement is required through
this Registration Standard for the 24 SC. For 10G products, the
registrants have the option of adding this statement immediately or
submitting the acute toxicity data in Table C for Agency review.
(Note: Submitted data may indicate the statement is required)
Rationale:
The high acute toxicity of oxamyl 24 SC formulations creates an
unacceptable risk if existing formulations are applied in such areas
especially if frequented by children. Extrapolated data would
indicate that 10G formulations may also pose an unacceptable risk in
these situations. However, due to the nature of granular
formulations, it possible that these products may not pose such
unacceptable risk. Registrants of 10G products therefore have the
option of submitting the appropriate acute toxicity data to evaluate
such potential risk or choosing not to submit such data and including
the prohibition.
14. Continuation of Registration
While the required data are under development, currently registered
manufacturing use products (MPs) and end use products (EPs) containing
oxamyl as the sole active ingredient may be sold, distributed,
formulated and used, subject to the terms and conditions specified in
this Standard. Registrants must provide or agree to develop
additional data, as specified in the Data Appendices, in order to
maintain existing registrations.
Rationale: Under FIFRA, the Agency may choose not to cancel or
withhold registration 'if data are missing or are inadequate (see FIFRA
sec. 3(c)(2)(B) and 3(c)(7)). The issuance of this sta'ndard provides
a mechanism for identifying data needs. These data will be reviewed
and evaluated, after which the Agency will determine if additional
regulatory actions are necessary.
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B. CRITERIA FOR REGISTRATION
To be registered or reregistered under this Standard, manufacturing-
use (MP) and end-use (EP) products must contain oxamyl as the sole
active ingredient, bear required labeling, and conform to the product
composition, acute toxicity limits, and use pattern requirements
listed in this document.
The applicant for registration or reregistration of MP and/or EP
products subject to this Standard must comply with all terms and
conditions described, including submission of an up-to-date
Confidential Statement of Formula, submission of revised labeling,
commitment to fill data gaps on the schedules as specified by the
Agency and, when applicable, offer to pay compensation as required by
sections 3(c)(l)(D) and 3(c)(2)(D) of the Federal Insecticide,
Fungicide, and Rodenticide Act (FIFRA), as amended, 7 U.S.C.
136(c)(l)(D) and 136(c) (2 ) (D) . Registrants of end-use products who
qualify for the Formulator's Exemption must submit five (5) copies of
draft labeling incorporating the unique label statements identified in
Section D.
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C. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Standard
To conform to this standard, MP and EP products must contain oxamyl
as the sole active ingredient. Each formulation proposed for
registration must be fully described with an appropriate certification
of limits, stating maximum and minimum amounts of the active and
intentionally added inert ingredients present in their products, as
well as impurities found at levels greater than 0.1%.
2. Acute Toxicity Limits
The Agency will consider registration of technical grade,
manufacturing-use, or end-use products containing oxamyl, provided the
product is supported by appropriate acute toxicity data and the
labeling for the product bears appropriate precautionary statements
for the toxicity category in which the product is placed. Oxamyl MPs
and 24SC end-use products are in toxicity category I and the
appropriate signal word is DANGER.
3. Use Patterns
To be registered under this Standard, manufacturing-use products must
be labeled for formulation into other manufacturing-use products or
into end-use products bearing federally registered uses. End-use
products must bear federally registered uses. Appendix III lists all
federally registered uses as well as approved maximum application
rates and frequencies.
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D. REQUIRED LABELING
All products must bear appropriate labeling as specified in 40 CFR
162.10, PR Notices 83-2, 83-3, 87-4, 87-5, and below. Appendix II
contains further information on label requirements.
Pesticide products containing oxamyl as the active ingredient may not
be released for shipment by the registrant after August 1, 1988 unless
the product bears amended labeling which complies with the
requirements of this standard.
Pesticide products containing oxamyl as the active ingredient may not
be distributed, sold, offered for sale, held for sale, shipped,
delivered for shipment, or received and (having been so received)
delivered or offered to be delivered by any person after August 1,
1989 unless the product bears amended labeling which complies with
the requirements of this Standard.
Labeling for the protection of endangered species are required as per
PR Notices 87-4 and 87-5 issued May 1, 1987.
All Products
1. Ingredients Statement
Registrants of all oxamyl products are required to revise their labels
to the following format:
ACTIVE INGREDIENT:
Oxamyl Methyl N'N•-dimethyl-N-[(methylcarbamoyl)oxy]-
1-thiooxamimidate %
INERT INGREDIENTS: % -
Manufacturing Use Products
9
1. Use Pattern Statements
All manufacturing-use oxamyl products must state that they are
intended for formulation into ^ther MPs or end-use products for uses
accepted by the U.S. Environmental Protection Agency. The labeling
must specify those use patterns listed under Use Patterns as Appendix
III. No uses may be included on any label where the registrant fails
to agree to comply with the data requirements in TABLE A for that
pattern of use.
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2. Environmental Hazards
The following revised environmental hazard statement must appear on
all MP labels:
"This pesticide is toxic to wildlife. Do not discharge effluent
containing this product into lakes, streams, ponds, estuaries, oceans
or public waters unless this product is specifically identified and
addressed in an NPDES permit. Do not discharge effluent containing
this product to sewer systems without previously notifying the sewage
treatment plant authority. For guidance contact your State Water
Board or Regional Office of the EPA."
3.Protective Clothing and Equipment
The following statement must appear on the Manufacturing Use Product:
"HANDLE THE CONCENTRATE ONLY WHEN WEARING THE FOLLOWING PROTECTIVE
CLOTHING AND EQUIPMENT:
Wear a protective suit of one or two pieces that covers all parts of
the body except the head, hands, and feet. Wear chemical resistant
gloves, chemical -resistant apron, and chemical resistant shoes, shoe
coverings, or boots. Wear goggles or a face shield. Wear a pesticide
respirator approved by the National Institute for Occupational Safety
and Health (NIOSH) and the Mine Safety and Health Administration
(MSHA)."
End Use Products
1.Environmental Hazards Statements
a. Oxamyl 24% SC
"This pesticide is toxic to wildlife and aquatic invertebrates.
Drift and runoff may be hazardous to aquatic organisms in neighboring
areas. Do not apply directly to water or wetlands (swamps, bogs,
marshes, and potholes). Do not contaminate water by cleaning of
equipment or disposal of wastes."
b. Oxamyl 10% G
"This product is toxic t^ wildlife. Cover, collect, or incorporate
granules spilled on soil -surfaces. Do not contaminate water by
cleaning of equipment or disposal of wastes."
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2. Required Bee Caution
a. Oxamyl 24% SC:
"This product is highly toxic to bees exposed to direct treatment or
residues on blooming crops or weeds. Do not apply this product or
allow to drift to blooming crops or weeds if bees are visiting the
treatment area."
3. Special Precaution for Ornamental and Potted Plants:
a. Oxamyl 24% SC:
The following statement must appear in the directions for use
concerning ornamental and potted plants:
"For use only in commercial greenhouses and nurseries. Do not apply
this product to interior plantscapes or potted plants in or around
domestic areas such as homes, shopping malls, or commercial
buildings."
b. Oxamyl 10% G:
The above statement regarding ornamental or potted plants must appear
on the label or the registrant may submit the acute toxicity data in
Table C. to determine if such statement is not appropriate.
4.Reentry Statement:
The following statement must appear on the labeling of agricultural
end use products which are applied to crops whose culture may involve
hand labor tasks:
" Do not enter treated areas for 48 hours after application unless
protective clothing is worn, as described in the product labeling"
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5. Restricted Use Statement
The following restricted use statement must appear on the front panel
of all 24 SC products. This statement must also appear on 10G labels
unless the acute toxicity data (in Table C) indicate that the product
is not a candidate for restricted use on the basis of acute toxicity.
In such cases, "Acute Toxicity And" may be deleted from the statement.
"RESTRICTED USE PESTICIDE
Due to Acute Toxicity
And Toxicity to Birds and Mammals
For retail sale to and use only by certified applicators or persons
under their direct supervision and only for those uses covered by the
certified applicator's certification."
6c Rotational Crop Statement
All end use products must have the following crop rotation statement:
"Do not plant crops other than those with registered oxamyl uses
within 6 months after the last application."
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"7. Protective Clothing and Work Safety
a. All Products.
"WEAR THE FOLLOWING PROTECTIVE CLOTHING AND EQUIPMENT DURING HANDLING,
MIXING, LOADING, APPLICATION, EQUIPMENT AND CLEANING, DURING EARLY
REENTRY TO TREATED AREAS, AND DURING DISPOSAL OF THE PESTICIDE:
Wear a protective suit of one or two pieces that covers all parts of
the body except the head, hands, and feet. Wear chemical-resistant
gloves, chemical-resistant apron, and chemical resistant shoes, shoe
coverings or boots. Wear goggles or faceshield and a pesticide
respirator approved by the National Institute for Occupational Safety
and Health (NIOSH) and/or the Mine Safety Health Enforcement
Administration (MSHA). A chemical resistant hat or hood must be worn
if the application is likely to result in overhead exposure, such as
during air blast applications.
During application from a tractor with a completely enclosed cab or
aerially with an enclosed cockpit, a long sleeve shirt and long legged
pants may be worn in place of the above protective clothing. Chemical
resistant gloves and an approved respirator must be available in the
cab or cockpit, and the gloves must be worn when exiting. Note that
this clothing is inadequate to protect you during equipment repair,
equipment cleaning, reentry, or during pesticide disposal.
IMPORTANT! Always wash hands, face and arms with soap a-nd water
before eating, smoking, drinking or toileting.
AFTER WORK: Wash gloves with'soap and water before removing. Take off
all clothing and shoes. Shower using soap and water. Wear only clean
clothes. Do not use contaminated clothing. Wash protective clothing
and equipment with soap and water after each use. Personal and
protective clothing worn during use must be laundered separately from
household articles. Clothing and protective equipment heavily
contaminated or drenched with oxamyl must be destroyed according to
state and local regulations.
<.
HEAVILY CONTAMINATED OR DRENCHED CLOTHING CANNOT BE ADEQUATELY
DECONTAMINATED.
Respirators should be cleaned and cartridges replaced according to
instructions included with the respirator. Replace gloves frequently.
DURING AERIAL APPLICATION, HUMAN FLAGGERS MUST BE IN A TOTALLY
ENCLOSED VEHICLE."
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be For the 24 SC only, the following wording may appear on the
label:
"If mixing or loading the concentrate with a closed system, a long
sleeve shirt and long-legged pants may be substituted for the
protective suit and respirator. Appropriate protective clothing and
equipment must still be worn during application, equipment repair,
equipment cleaning, early reentry, and disposal."
8.Ground Water Advisory
The following statement is required for all end-use products.
it
GROUND WATER ADVISORY
Residues of (product name) can seep or leach through soil and can
contaminate ground water which may be used for drinking. Users are
advised not to apply (product name) where the water table is close to
the surface and where soils are very permeable, i.e., well-drained
soils such as loamy sands. Local Agricultural Agencies can provide
information on the soil types i-n your area and the location of the
ground water. "
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V. PRODUCTS SUBJECT TO THIS STANDARD
All products containing one or more of the pesticides identified in
Section II.A. are subject to certain requirements for data submission
or changes in composition, labeling or packaging of the product. The
applicable requirements depend on whether the product is a
manufacturing or end use product and whether the pesticide is the sole
active ingredient or one of multiple active ingredients.
Products are subject to this Registration Standard as follows:
A. Ma^uf_ac_t.ur.ing_use_pro_du_ct_s containing oxamyl as the sole active
ingredient are subject to:
1. The restrictions (if any) upon use, composition, or
packaging listed in Section IV, if they pertain to the
manufacturing use product.
2. The data requirements listed in Tables A and B.1
3. The labeling requirements specified for manufacturing
use products in Section IV.
4. Administrative requirements (application forms, Confiden-
tial Statement of Formula, data compensation provisions)
associated with reregistration.
1 Data requirements are listed in the three tables in Appendix I of
this registration standard. The guide to tables in that Appendix
explains how to read the Tables.
Table A lists generic data requirements applicable to all products
containing the pesticide subject to this registration standard. Table
B lists product-specific data applicable to manufacturing use
products. The data in Tables A and B need not be submitted by a
producer who is eligible for the formulator's exemption for that
a,'ive ingredient.
Table C lists product-specific data applicable to end use products.
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B. Ma_nu^c^ur_inc[_u_se_p_roduct£ containing oxamyl as one of •
multiple active ingredients are subject to:
The data requirements listed in Table A and labeling requirements
specified for manufacturing use products.
C. End_use_p_roducts containing oxamyl as the sole active
ingredient are subject to:
1. The restrictions (if any) upon use, composition, or packaging
listed in Section IV if they pertain to the end use product.
2. If eligible for the formulator's exemption2, the data requirements
listed in Table C.
3. If not eligible for the formulator's exemption, the data
requirements listed in Table A and the data requirements listed in
Table C.
4. The labeling requirements specified for end use products in
Section IV.
* solvents or diluents must be declared as inerts. The
Agency does not have data indicating that these solvents are
insecticidal.
If you purchase from another producer and use as the source of your
active ingredient only EPA-registered products, you are eligible for
the formulator's exemption for generic data concerning that active
ingredient (Table A) and product-specific data for the registered
manufacturing use product you purchase (Table B).
Two circumstances nullify this exemption:
1) If you change sources of active ingredient to an unregistered
product, formulate your own active ingredient, or acquire your active
ingredient form a firm with ownership in common with yours, you
individually lose the exemption and become subject to the data
requirements in Table A.
2) If no producer subject to the generic data requirements in Table A
agrees to submit the required data, all end use producers lose the
exemption, and become subject to those data requirements.
34
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D. End_uj5e_£r;oduc;t£ containing this pesticide as one of multiple
active ingredients are subject to:
a. If not eligible for the formulator's exemption, the data
requirements listed in Tables A and C.
b. If eligible for the formulator's exemption, the data requirements
listed in Table C.
c. The labeling requirements specified for end use products specified
in Section IV.
35
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VI. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
This portion of the Registration Standard is a notice issued under the
authority of FIFRA sec. 3(c)(2)(B). It refers to the data listed in
Table A, which are required to be submitted by registrants to maintain
in effect the registration of products containing this active
ingredient.
A. What are generic data?
Generic data pertain to the properties or effects of a particular
active ingredient. Such data are relevant to an evaluation of all
products containing that active ingredient regardless of whether the
product contains other ingredients, (unless the product bears labeling
that would make the data requirement inapplicable).
Generic data may also be data on a "typical formulation" of a product.
"Typical formulation" testing is often required for ecological effects
studies and applies to all products having that formulation type.
These are classed as generic data, and are contained in Table A.
B. Who must submit generic data?
All current registrants are responsible for submitting generic data in
response to a data request under FIFRA sec. 3(c)(2)(B) (DCI Notice).
EPA has decided, however, not to require a registrant who qualifies
for the formulator's exemption (FIFRA sec. 3(c)(2)(D) and } 152.85) to
submit generic data in response to a DCI notice if the registrant who
supplies-the active ingredient in his product is complying with the
data request.
If you are not now eligible for a formulator's exemption,
you may qualify for one if you change your source of supply
to a registered source that does not share ownership in
common with your firm. If you choose to change sources of
supply, the Confidential Statement of Formula must identify
the new source(s) and you must submit a Formulator's Exemption
Statement form.
3 Registrations -ranted after issuance of this Standard will be
conditioned upon submission or citation of the data listed in this
Registration Standard.
36
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If you apply for a new registration for products containing this
active ingredient after the issuance of this Registration Standard,
you will be required to submit or cite generic data relevant to the
uses of your product if, at the time the application is submitted, the
data have been submitted to the Agency by current registrants. If the
required data have•not yet been submitted, any new registration will
be conditioned upon the new registrant's submission or citation of the
required data not later than the date upon which current registrants
of similar products are required to provide such data. See FIFRA sec.
3(c)(7)(A). If you thereafter fail to comply with the condition of
that registration to provide data, the registration may be canceled
(FIFRA sec. 6(e)) .
C. What generic data must be submitted?
You may determine which generic data you must submit by consulting
Table A. That table lists the generic data needed to evaluate current
uses of all products containing this active ingredient, the uses for
which such data are required, and the dates by which the data must be
submitted to the Agency.
D. How to comply with PCI requirements.
Within 90 days of your receipt of this Registration Standard, you must
submit to* EPA a completed copy of the form entitled "FIFRA Section
3(c)(2)(B) Summary Sheet" (EPA Form 8580-1, enclosed) for each of your
products. On that form you must state which of the following six
methods you will use to comply with the DCI requirements:
1. You will submit the data yourself.
2. You have entered into an agreement with one or more registrants
to jointly develop (or share in the cost of developing) the data,
but will not be submitting the data yourself. If you use this method,
you must state who will submit the data on which you will rely. You
must also provide EPA with documentary evidence that an agreement has
been formed which allows you to rely upon the data to be submitted.
Such evidence may be: (1) your letter offering to join in an
agreement and the other registrant's acceptance of your offer, (2) a
written statement by the parties that an agreement exists, or (3) a
written statement by the person who will be submitting the data that
you may rely apon its submission. The Agency will also require
adequate assurance that the person whom you sta .« will provide the
data is taking appropriate steps to secure it. The agreement to
produce the data need not specify all of the terms of the final
arrangement between the parties or a mechanism to resolve the terms.
37
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3. You have attempted to enter into an agreement to jointly
develop data, but no other registrant has accepted your offer.
You request that EPA not suspend your registration for non-compliance
with the PCI. EPA has determined that, as a general policy, it will
not suspend the registration of a product when the registrant has in
good faith sought and continues to seek to enter into a data
development/cost sharing program, but the other registrants developing
the data have refused to accept its offer. [If your offer is
accepted, you may qualify for Option 2 above by entering into an
agreement to supply the data.]
In order to qualify for this method, you must:
a. File with EPA a completed "Certification of Attempt to Enter into
an Agreement with other Registrants for Development of Data" (EPA Form
8580-6, enclosed).
b. Provide us with a copy of your offer to the other registrant and
proof of the other registrant's receipt of your offer (such as a
certified mail receipt). Your offer must, at a minimum, contain the
following language or its equivalent:
[Your company name] offers to share in the burden of
producing the data required pursuant to FIFRA sec.
3(c)(2)(B) in the [name of active ingredient] Registration
Standard upon terms to be agreed or failing agreement
to be bound by binding arbitration as provided by FIFRA
section 3(c)(2)(B)(iii).
The remainder of your offer may not in any way attempt to limit this
commitment. If the other registrant to whom your offer is made does
not accept your offer, and if the other registrant informs us on a DCI
Summary Sheet that he wil'l develop and submit the data required under
the DCI, then you may qualify for this option. In order for you to
avoid suspension under this method, you may not later withdraw or
limit your offer to share in the burden of developing the data. In
addition, the other registrant must fulfill its commitment to develop
and submit the data.
4. You request a waiver of the data requirement. if you believe that
a data requirement does not (or should not) apply to your product or
its uses, you must provide EPA with a statement of the reasons why you
believe this is so. Your statement must address the specific
composition or use factors that lead you to believe that a requirement
does not apply. Since the Agency has car^./ully considered the
composition and uses of pesticide products in determining that a data
requirement applies, EPA does not anticipate that many waivers will be
granted. A request for waiver does not extend the time-frames for
developing required data, and if your waiver request is denied, your
registration may be suspended if you fail to submit the data.
38
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5. You request that EPA amend your registration by deleting the
H§^§_^2^;_whJ:ch_t;he_da/ta_a^;e_needed_._ You are not required to submit
data for uses which are no longer on your label.
6. You request voluntary cancellation of the registration of your
product(s) for which the data are needed.
E. Procedures for requesting a change in testing protocol.
If you will generate the required data and plan to use test procedures
which deviate from (or are not specified in) either EPA's Pesticide
Assessment Guidelines or the Reports of Expert Groups to the Chemicals
Group, Organization for Economic Cooperation and Development (OECD)
Chemicals Testing Programme, you must submit for EPA approval the
protocols you propose to use.
You should submit your protocols before beginning testing and await
EPA approval, because the Agency will not ordinarily accept as
sufficient studies using unapproved protocols. A request for protocol
approval will not extend the timeframe for submission of the data, nor
will extensions generally be given to conduct studies due to submittal
of inappropriate protocols.
F. Procedures for requesting extensions of time.
If you think that you will need more time to generate the data than is
allowed by EPA's schedule, you may submit a request for an extension
of time. Any request for a time extension which is made as an initial
response to a section 3(c)(2)(B) request notice must be submitted in
writing to the Product Manager listed at the end of this section and
must be made before the deadline for response. Once dates have been
committed to and EPA has accepted these commitments, any subsequent
requests for a time extension must be submitted in writing to the
Office of Compliance Monitoring.
EPA will view failure to request an extension before the response
deadline as a waiver of any future claim that there was insufficient
time to submit the data. While EPA considers your request, you must
strive to meet the deadline for submitting the data.
The extension request should state the reasons why you believe that an
extension is necessary and the steps you have taken to meet the
testing deadline. Time extensions normally will not be granted due to
problems with laboratory capacity or adequacy of funding, since the
Agency believes that with proper planning these can be overcome. Time
extensions may be considered when joint data development is planned,
or when the Agency must approve a new or modified protocol before the
study can be begun.
39
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A request for an extension does not extend the timeframe for
submission of the data. If EPA denies your request for a time
extension and you do not submit the data as requested, EPA may begin
proceedings to suspend the registrations of your products.
G. Existing stocks provision upon suspension or cancellation—
The Agency has determined that if a registration is suspended for
failure to respond to a DCI request under FIFRA sec. 3 (c) (2) (B)-, an
existing stocks provision is not consistent with the Act.
Accordingly, the Agency does not anticipate granting permission to
sell or distribute existing stocks of suspended product except in rare
circumstances. If you believe that your product will be suspended or
canceled and that an existing stocks provision should be granted, you
have the burden of clearly demonstrating to EPA that granting such
permission would be consistent with the Act. The following
information must be included in any request for an existing stocks
provision:
1. Explanation of why an existing stocks provision is
necessary, including a statement of the quantity of
existing stocks and your estimate of the time required
for their sale or distribution; and
2. Demonstration that such a provision would be consis-
tent with the provisions of FIFRA.
40
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VII. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Under its DCI authority, EPA has determined that certain product-
specific data are required to maintain your registrations in effect.
Product-specific data are derived from testing using a specific
formulated product, and, unlike generic data, generally support only
the registration of that product. All such data must be submitted by
the dates specified in this Registration Standard.
If you have a manufacturing use product, these data are listed in
Table B. If you have an end use product, the data are listed in Table
Co As noted earlier, the Agency has decided that it will not
routinely require product-specific data for end use products at this
time. Therefore, Table C may not be contained in this Registration
Standard; if there is no Table C, you are not required to submit the
data at this time.
In order to comply with the product specific data requirements, you
must follow the same procedures as for generic data. See Section IV.D,
E, F, and G. You should note, however, that product chemistry data
are required for every product, and the only acceptable responses are
options IV.D.I. (submit data) or I V.D . 6 . ( cance11 ation of
registration).
Failure to comply with the product-speci'fic data requirements for your
products will result in suspension of the product's registration.
41
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VIII. REQUIREMENT FOR SUBMISSION OF REVISED LABELING
FIFRA requires each product to be labeled with accurate, complete and
sufficient instructions and precautions, reflecting the Agency's
assessment of the data supporting the product and its uses. General
labeling requirements are set out in 40 CFR 162.10 (see Appendix II -
LABELING and SUMMARY). In addition, labeling requirements specific to
products containing this pesticide are specified in Section IV.D of
this Registration Standard. Applications submitted in response to
this notice must include draft labeling for Agency review.
If you fail to submit revised labeling as required, which complies
with 40 CFR 162.10 and the specific instructions in Section IV.D., EPA
may seek to cancel or suspend the registration of your product under
FIFRA sec. 6.
42
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IX. INSTRUCTIONS FOR SUBMISSION
A. Manufacturing Use Products (MPs) containing Oxamyl as sole active
ingredient.
1. Within 90 days from receipt of this document, you must submit to
the Product Manager in the Registration Division for each product
subject to this Registration Standard:
a. The "FIFRA Section 3(c)(2)(B) Summary Sheet" (EPA
Form 8580-1), with appropriate attachments./4
b. Confidential Statement of Formula (EPA Form 8570-4),
attached separately.
c. Formulator's Exemption Statement, if applicable.
d. Evidence of compliance with data compensation
requirements of FIFRA sec. 3(c)(1)(D). Refer to 40 CFR
152.80-152.99.
2. Wi.^hiLji_9_montJ}s from receipt of this document you must submit to
the Product Manager:
a. Two copies of any required product-specific data
(See Table B).
b. Five (5) copies of draft labeling, including the
container label and any associated supplemental labeling.
Labeling should be either typewritten text on 8-1/2 x 11
inch paper or a mockup of the labeling suitable for
storage in 8-1/2 x 11 files. The draft label must
indicate the intended colors of the final label, clear
indication of the front panel of the label, and the
intended type sizes of the text.
c. Product Specific Data Report.
4 If on the Summary Sheet, you commit to develop the data, present
arguments that a data requirement is not applicable or should be
waived, or submit protocols or modified protocols for Agency review,
you must submit a copy of the Summary Sheet (and any supporting
information) to the Office of Compliance Monitoring, which will be
monitoring the data rrenerated in response to this notice. This
submission is in addi^on to responding to the Product Manager, and
should be submitted to the Office of Compliance Monitoring at the
address given at the end of this section. (Actual studies are not to
be submitted to the Office of Compliance Monitoring.)
43
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3. Within the times set forth in Table A, you must submit to the
Registration Division all generic data, unless you are eligible for
the formulator's exemption. If for any reason any test is delayed or
aborted so that the schedule cannot be met, immediately notify the
Product Manager and the Office of Compliance Monitoring of the
problem, the reasons for the problem, and your proposed course of
action.
B. Manufacturing Use Products containing Oxamyl in combination with
other active ingredients.
1. Within 90 days from receipt of this document, you must submit to
the Product Manager in the Registration Division:
a. FIFRA sec. 3(c)(2)(B) Summary Sheet, with appropriate
attachments (EPA Form 8580-1).
b. Confidential Statement of Formula (EPA Form 8570-4),
attached separately.
c. Formulator's Exemption Statement, if applicable.
2. Within 9 months from receipt of this document you must submit five
(5) copies of draft labeling.
3. Within the time frames set forth in Table A, you must submit to
the Registration Division all generic data, unless you are eligible
for the formulator's exemption. If for any reason any test is delayed
or aborted so that the schedule cannot be met, immediately notify the
Product Manager and the Office of Compliance Monitoring of the
problem, the reasons for the problem, and your proposed course of
action.
C. End Use Products containing Oxamyl alone or in combination with
other active ingredients.
1. WrthAj}_2£_day^ from receipt of thi.s document, you must submit to
the Product Manager in the Registration Division:
a. FIFRA Section 3(c)(2)(B) Summary Sheet, with
appropriate attachraentsS (EPA Form 8580-1).
b. Confidential Statement of Formula (EPA Form 8570-4),
attached separately.
c. Formulator's Exemption Statement, if applicable.
44
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2. Within 9 months from receipt of this document you must submit
to the Product Manager:
a. Two copies of any product-specific data, if required
by Table C.
b. Product Specific Data Report, if Table C lists
required product-specific data.
c. Five copies of draft labeling, including the container label and
any associated supplemental labeling. Labeling should be either
typewritten text on 8-1/2 x 11 inch paper or a mockup of the labeling
suitable for storage in 8-1/2 x 11 inch files. The draft labeling
must indicate the intended colors of the final label, clear indication
of the front panel of the label, and the intended type sizes of the
text. End use product labeling must comply specifically with the
instructions in Section IV (Regulatory Position and Rationale).
E. Addresses
Dennis Edwards
Product Manager 12
Registration Division (TS-767C)
Office of Pesticide Programs
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460
The address for submissions to the Office of Compliance
Monitoring is:
Laboratory Data Integrity Program
Office of Compliance Monitoring (EN-342)
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460.
45
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APPENDIX I
DATA APPENDICES
46
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GUIDE TO TABLES
Tables A, B, and C contain listings of data requirements for the
pesticides covered by this Registration Standard.
Table A contains generic data requirements that apply to
the pesticide in all products, including data requirements
for which a "typical formulation" is the test substance.
Table B contains product-specific data requirements that
apply only to a manufacturing use product.
Table C contains product-specific data requirements that
apply only to an end use product.
The data tables are generally organized according to the following
format:
1. Data Requirement (Column 1). The data requirements are listed in
the order in which they appear in 40 CFR Part 158. The reference
numbers accompanying each test refer to the test protocols set out in
the Pesticide Assessment Guidelines, which are available from the
National Technical Information Service, 5285 Port Royal Road,
Springfield, VA 22161.
2. Test Substance (Column 2). This column lists the composition
of the test substance required to be used for the test, as follows:
TGAI = Technical grade of the active ingredient
PAI = Pure active ingredient
PAIRA = Pure active ingredient, radio labeled
TEP = Typical end use formulation
MP = Manufacturing use product
EP = End use product
Any other test substances, such as metabolites, will be specifically
named in Column 2 or in footnotes to the table.
47
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3. Use pattern (Column 3). This column indicates the use patterns to
which the data requirement applies. Use patterns are the same as
those given in 40 CFR Part 158. The following letter designations are
used for the given use patterns:
A = Terrestrial, food
B = Terrestrial, non-food
C = Aquatic, food
D = Aquatic, non-food
E = Greenhouse, food
F = Greenhouse, non-food
G = Forestry
H = Domestic outdoor
I = Indoor
Any other designations will be defined in a footnote to the table.
4. Does EPA have data? (Column 4). This column indicates one
of three answers:
YES - EPA has data in its files that completely satisfy
this data requirement. These data may be cited by
other registrants in accordance with data compensation
requirements of Part 152, Subpart E.
PARTIALLY - EPA has some data in its files, but such data
do not fully satisfy the data requirement. In some cases,
the Agency may possess data on one of two required species,
or may possess data on one test substance but not all.
The term may also indicate that the data available to
EPA are incomplete. In this case, when the data are
clarified, or additional details of the testing submitted
by the original data submitter, the data may be determined
to be acceptable. If this is the case, a footnote to
the table will usually say so.
NO - EPA either possesses no data which are sufficient
to fulfill the data requirement, or the data which EPA
does possess are flawed scientifically in a manner that
cannot be remedied by clarification or additional infor-
mation.
5. Bibliographic citation (Column 5). If the Agency has acceptable
data in its files, this column lists the identifying number of each
study. This normally is the Master Record Identification (MRID)
number, but may be a GS number if no MRID number has been assigned.
Refer to the Bibliography Appendices for a complete citation of the
study.
48
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6. Must additional data be submitted? (Column 6). This column
indicates whether the data must be submitted to the Agency. If column
3 indicates that the Agency already has data, this column will usually
indicate NO. If column 3 indicates that the Agency has only partial
data or no data, this column will usually indicate YES. In some
cases, even though the Agency does not have the data, EPA will not
require its submission because of the unique characteristics of the
chemical; because data on another chemical can be used to fulfill the
data requirement; or because the data requirement has been waived or
reserved. Any such unusual situations will be explained in a footnote
to the table. N/A indicates that the data requirement is not
applicable to the use pattern.
7. Timeframe for submission (Column 7). If column 5 requires that
data be submitted, this column indicates when the data are to be
submitted, based on the receipt date of the Registration Standard.
The timefraraes are those established either as a result of a previous
Data Call-in letter, or standardized timeframes established by PR
Notice 85-5 (August 22, 1985).
80 Footnotes (at the end of each table). Self-explanatory.
49
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
Test
Substance
Does EPA Bibliographic
Have Data?!/ Citation I/
Must Additional Timeframe
Data be for
Submitted? Submission?/
156.120 Product Chemistry
Product Identity and Composition
61-2 - Description of Beginning TGAI
Materials and Manufacturing
Process
61-3 - Discussion of Formation of TGAI
Impurities
Analysis and Certification of
Product ingredient?
62-1 - Preliminary Analysis TGAI
Yes
Yes
Yes
6 Months
6 Months
12 Months
0 Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
63-5 - Melting Point
TGAI
TGAI
TGAI
TGAI
Yes
Yes
Yes
Yes3/
6 Months
6 Months
6 Months
6 Months
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
uatd Kequiremenc Test
Substance
1 SH 1 /Tl Prortnrt rhpmf^frv frnntinnpdl
1 ^O • 1 fc.V/ I • \7UUv> V Lilldli 1 j L I Jr I l_ Ull v 1 IIUCVJ |
Physical and Chemical Characteristics
[continued]
63-6 - Boiling Point
63-7 - Density, Bulk Density, or
Specific Gravity
63-8 - Solubility TGAI
63-9 - Vapor Pressure TGAI
63-10 - Dissociation Constant TGAI
63-11 - Octanol/Water Partition
Coefficient
63-12 - pH
63-13 - Stability
TGAI
TGAI
or PAI
or PAI
or PAI
PAI
TGAI
TGAI
Does EPA Bibliographic Must Additional
Have Data?!/ Citation I/ Data be
Submi tted?
Yes4/
Yes
Yes
Yes
Yes
Yes
Yes
Yes.
1 i me frame
for
Submissi on2/
6 Months
6 Months
6 Months
6 Month's
6 Months
6 Months
6 Months
6 Months
Other Requirements:
64-1 - Submittal of Samples
TGAI, PAI
Reserved5/
i; ilthnuah oroduct chemistry data may have been submitted in the past, the Agency has determined thai ' ~
theledatS must be resubmitted for each pesticide. New requirements have been introduced and prev.ously subm.tted
these aa" "";;;. trt Therefore bibliographic citations for the old data are not applicable.
21 D^'dates refer" to the number of 'months following receipt of this Registration Standard by the registrant, unless
3, £u^dei}ndtneatecdhnical is a solid at room temperature.
li S^u rid f the technical is a liquid at room temperature.
\'/ HqslmP?es are needed, the Agency will request them.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
"•*
c_n
Data Requirement
158.130 Environmental Fate
DEGRADATION STUDIES-LAB:
161-1 - Hydrolysis
Photodegradation
161-2 - In Water
161-3 - On Soil
161-4 - In Air
METABOLISM STUDIES-LAB:
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
ifi?_4 - Aerobic Aauatic
Test
Substance
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
Use
Pattern
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
Does EPA
Have Data?
Partially
Partially
No
No
Yes
No
No
NO .
Bibliographic Must Additional Timeframe
Citation Data be for
Submitted? Subnhssionl
00040494 Yes 9 Months
00040494 Yes 9 Months
7
N/A
8
N/A
00063012 No
2
Yes 27 Months
7
N/A
7
N/A
MOBILITY STUDIES:
163-1 - Leaching and
Adsorpti on/Desorpti on
PAIRA
ABEF Partially
00040494
00141395
00154748
Yes
12 Months
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158.130 Environmental Fatekonti
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
DISSIPATION STUDIES-FIELD:
164-1 - Soil
164-2 - Aquatic (Sediment)
164-3 - Forestry
.3 164-4 - Combination and
Tank Mixes
164-5 - Soil , Lc..g-term
en
^ ACCUMULATION STUDIES:
165-1 - Rotational Crops
(confined)
165-2 - Rotational Crops
(field)
165-3 - Irrigated Crops
165-4 - In F1sh
.rr r T- A/iujtir WnntArQPt
lest Use
Substance Pattern
nued)
TEP ABEF
TEP ABEF
TEP ABEF
TEP
TEP
TEP
TEP ABEF
PAIRA ABEF
TEP ABEF
TEP
PAIRA ABEF
TEP
Does EPA
Have Data?
No
No
Yes
No
No
No
No
No
No
No
No
No
Bibliographic Must Additional Timeframe
Citation Data be for
Submitted? Submissionl
N/A8
N/A8
1492J1 Yes 27 Months/2
7
N/A
N/A7
N/A7
4
Reserved
Yes 39 Months/2
ReservedS
7
N/A
6
N/A
7
N/A
Organi sms
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TABLE A
GENERIC REQUIREMENTS FOR OXAMYL
158.130 Environmental Fate - Footnotes
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated.
2/ First progress report due 8 months after receipt of this Standard. Interim reports are due semi-annual ly
thereafter.
3/ Data are required on aged residues using a column leaching study indicating adequate identification of residues.
4/ Pending evaluation of information in soil studies 164-1.
5/ Pending results of confined rotational crop study.
6/ Octanol-watei partition coefficient is 0.33.
II Not required because the registered use patterns preclude the necessity for these studies.
8/ Not required because the appropriate protective equipment triggered by the study results already appears on
registered labels.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data
158.
132-1
132-2
132-3
132-4
158.
158.
201-1
201-1
Requirement
140 Reentry Protection
- Fol iar Dissipation
- Soil Dissipation
- Dermal Exposure
- Inhalation Exposure
75 Other Exposure Data
- Glove Permeabil i ty
142 Spray Drift
- Droplet Size Spectrum
- Drift Field Evaluation
Test
Substance
TEP2
TEP
TEP
TEP
TEP2
TEP2
TEP2
Use
Pattern
ABEF
A
ABEF
ABEF
ABEF
AB
AB
Does EPA Have.
Data?
Partial
No
Partial
Partial
No
No
No
Bibliographic Must Addi tional
Citation Data be Submitted?
163605 Yes3
Yes
163606 Yes3
163606 Yes3
Yes4
Yes6
Yes6
Time frame
for
21 Months
21 Months
27 Months
2? Months
9 Months5
12 Months
12 Months
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated.
2/ SC formulation only.
3/ Additional information is needed to complete estimation of reentry intervals. This information is needed for
conversion of the reported data to surface residue levels.
4/ Study using several materials and conducted according to methods in "Standard Test Method fo Resistance of
Protective C~c*hing to Permeation by Hazardous Liquid Chemicals", ASTM.
5/ Protocol required within 3 months of receipt of this Standard.
6/ The droplet size spectrum and the drift field evaluation data may be done together in order to evaluate the drop
spectra associated with actual field use patterns.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158.135 Toxicology
ACUTE TESTING:
81-1 - Acute Oral Toxicity - Rat
81-2 - Acute Dermal Toxicity -
Rabbit
81-3 - Acute Inhalation Toxicity
Rat
01
ON 81-7 - Acute Delayed
Neurotoxici ty- Hen
Test Use Does EPA
Substance Patterns Have Data?
TGAI ABEF Yes
TGAI ABEF Mo
- TGAI ABEF Yes
TGAI ABEF No
Bibliographic Must Additional
Citation Data be
Submitted?
063011 No
Yes
066902 No
066903
2
NA
Time frame
for
Submissi onl
9 Months
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise Indicated.
21 This study is not required since the subject compound is not an organophosphate.
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TABLE A
GENERIC DATA. REQUIREMENTS FOR OXAMYL
Data Requirement
158.135 Toxicology (continued)
SUBCHRONIC TESTING:
82-1 - 90-Day Feeding: Rodent
and Nonrodent (Dog)
82-2 - 21-Day Dermal - Rabbit
82-3 - 90-Day Dermal - Rabbit
82-4 - 90-Day Inhalation - Rat
82-5 - 90-Day Neurotoxici ty
Test
Substance
TGAI
TGAI
TGAI
TGAI
TGAI
Use
Patterns
ABEF
ABEF
ABEF
ABEF
ABEF
Does EPA
Have Data?
No
No
No
No
No
Bibliographic Must Additional
Citation Data be
Submitted?
No?
Yes
3
NA
3
NA
4
NA
Time frame
for
Submi ssi on!
7 Months
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated.
21 Not required under the present circumstances since chronic studies in the rat, dog and mouse are needed. The
registrant should be aware that subchronic studies are necessary to establish the MTD in rodent oncogenicity
studies.
3/ Requirement not applicable because of lack of serious exposure with registered use patterns.
4/ This study is not required since the compound is not an organophosphate.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data
158.1
Requi rement
35 Toxicology (continued)
Test
Substance
Use Does EPA
Patterns Have Data?
Bibliographic Must Addi ti ondl Timeframe
Citation Data be for
Submitted? Submission/1
CHRONIC TESTING:
83-1
83-2
83-3
83-4
- Chronic Toxicity -
Rodent and Non-Rodent
- Oncogenicity -
Mouse
Rat
- Teratogenici ty -
Rat
Rabbit
- Reproduction - Rat
2-generation
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
ABEF No
ABEF Yes
ABEF No
ABEF No
ABEF Yes
ABEF No
Yes2 42 Months3
076813 No
Yes 42 Months3
Yes 12 Months
063009 No
3
V 20 Months
CO
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated.
2/ Both Rodent and NonRodent Required.
3/ First progress report due 8 months after receipt of this Standard. Interim reports are due semi-annually
thereafter.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158.135 Toxicology (continued)
MUTAGENICITY TESTING:
84-2 - Gene Mutation
84-3 - Structural Chromosomal
Test
Substance
TGAI
TGA1
Use
Patterns
ABEF
ABEF
Does EPA Bibliographic
Have Data? Citation
No
No
Must Addi
Data be
Submitted?
Yes
Yes
tional Timeframe
for
Submissionl/
10 Months
10 Months
Aberration
84-4 - Other Genotoxic Effects
(ONA Damage)
SPECIAL TESTING
85-1 - General Metabolism
TGAI ABEF
PA1 or PAIRA ABEF
Yes
00040594
No
Yes
14 Months
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise Indicated.
21 First progress report due 8 months after receipt of this Standard. Interim reports are due semi-annual ly
thereafter.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data
Requl rement
Test
Substance
Use Does EPA Bibliographic Must Additional Timeframe
Patterns Have Data? Citation Data be for
Submitted? Submissionl/
58.145 Wildlife and Aquatic Organisms
AVIAN AND MAMMALIAN TESTING:
71-1
71-2
71-3
71-4
71-5
- Acute Avian Oral Toxlclty
- Avian Subacute Dietary
- Upland Game Bird
- Waterfowl
- Wild Mammal Toxlcity
- Avian Reproduction
-Upland Game Bird
-Waterfowl
- Simulated and Actual
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TEP3
AB
AB
AB
AB
AB
AB
AB
Yes
No
No
No
Yes
Yes
No
0094660 No
Yes
Yes
2
Reserved
0116610 - No
0116609 No
Yes4
9 Months
9 Months
48 MonthsS
Actual Field Testing -
Mammals and Birds
o\
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement Test Use Does EPA Bibliographic Must Additional Time frame
Substance Patterns Have Data? Citation Data be for
Submitted? Submissionl/
S8.145 Wildlife and Aquatic Organisms (continued)
-QUATIC ORGANISM TESTING
72-1
72-2
72-3
ON
72-4
- Freshwater Fish Toxicity
- Coldwater Species
- Warmwater Species
- Acute Toxicity to
Freshwater Invertebrates
- Acute Toxicity to Estuarine
and Marine Organisms
- Fish
- Shrimp
- Oyster
- Fish Early Life Stage,
and Aquatic Invertebrate
Life Cycle
- Fish
t — .,^«»*-aK»*atP
TGAI AB Yes 0066914 No
TGAI AB Yes 0066916 No
TGAI AB Yes 0094664 No
TGAI AB No Ves6
TGAI AB Yes 0113412 , No
TGAI AB Yes 0113414 No?
TGAI AB NO Ves8 15 Months9
TGAI AB Yes 0094664 No
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data? Citation Data be for
Submi tted? Submissionl/
156.145 Wildlife and Aquatic Organisms(continued)
AQUATIC ORGANISM TESTING
72-5 - Fish - Life Cycle TEP AB No N/A
10
72-6 - Aquatic Organism TEP AB No N/A
Accumulation
11
72-7 - Simulated or Actual Field TEP AB No Reserved
Testing
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated. . ,
2/ Reserved pending the results of field field studies and the necessity of dietary studies on mammals to assess
risks or interpret field studies.
\Jl A°th;»lthfield tesUnYwith birds$andemammaU'is required to support all uses of the 10 G formulation and all foliar
annlicatlons of 24%SC products. For the granular product, a field study using band applications on peanuts is
sSec flcalW Squired to support that uselunincorporated application). An additional field study with the granular
oreflrab y on Jomatoes) is required to support the other granular uses. Study design should include appropriate
(preferably on ™""/ • «J h1n r\Q determine pesticide-induced mortality and extent. For the 24% SC,
He °d stud e re requ ^do^eseuent of use Snd wildlife utilization), on potatoes induced wrt>my and the potent.at effec s „,, ,an breed g «" »^^^^"^gistrants are encouraged to
coniuuVth thfS c5' o erntn 11^^1111 studies prior to the initiation of field studies.
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
158.145 Mildllt^ and Aquatic Organisms (continued)
5/ Protocols must be submitted within 12 months. These protocols must include specific sites and a detailed outline
methodology and experimental design. Registrants are strongly encouraged to submit preliminary protocols within
6 months.
6/ 96 hour LC50 required based on the potential for runoff into estuarine areas from crop uses.
7/ Tests on the 24% SC satisfy requirements for the technical.
8/ Required for uses where estimated environmental concentrations exceed .01 the Fish LC50. These include all foliar
applications greater than 1.0 15 ai/A, soil applications of the 24X SC that are not incorporated, soil
applications of the 10 G at 2.0 Ib. ai/A or greater, and applications by in-furrow irrigation water that do not
specify methods (e.g. retention) to prevent the runoff of treated water.
9/ First progress report due 8 months after receipt of this Standard. Interim reports are due semi-annually
thereafter.
107 Study not required because the octanol/water partition coefficient is O.JJ
III Maximum estimated environmental concentrations in aquatic habitats exceed 1/2 the LC50 for the most sensitive
aquatic Invertebrate from foliar applications at 2.0 Ib ai/A and above, from granular soil treatments for peanuts
a-nd ornamentals and from liquid soil treatments for eggplant, peppermint, spearmint, and garlic (SLNs from
CA 4 OR? Aquatic residue monitoring studies are reserved, pending an evaluation of required environmental fate
studies Ac?ual field studies for aquatic invertebrates are reserved for the same uses and will be required if
?} aquatic residue monitoring demonstrates that residues exceed 1/2 the LC50 for the most sensitive aquatice
Invertebrates.
-------
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158.155
Nontarget
NONTARGET INSECT
141-1 -
141-2 -'
141-4 -
141-5 -
Honeybee
LD50
Honeybee
residues
Honeybee
feeding s
Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data? Citation Data be for
Submitted? Submission I/
Insects
TESTING - POLLINATORS:
Acute Contact TGAI AB Yes 00036935 No
05001991
2 3 4
- toxicity of TEP AB No Yes 15 Months
on foliage
subacute TEP AB No ReservedS
tudy
Field testing for TEP AB No N/A
pol 1 i nators
I/ Due dates refer to the number of months following receipt of this Registration Standard by the registrant,
unless otherwise indicated.
21 SC formulation
3/ As data from the acute toxicity study indicate a high toxicity, residual toxicity data are required.
4/ First progress report due 8 months after receipt of this Standard. Interim reports are due semi-annual ly
thereafter.
5/ Reserved pending development of test methodology.
-------
TARI.E A
GENERIC DATA REQUIREMENTS FDR OXAMYI,
Data Requirement
Test
Substance
Does EPA
Have Data?
$158.125 Residue Chemistry
171-2 -.Chemical Identity^/
171-3 - Directions for Use (See Index)
171-4 - Nature of Residue
(metabolism)
Plants
Livestock
G\
171-4 - Residue Analytical
Methods
Plants and animal
residues
171-4 - Storage Stability Data
Yes
PAIRA
Partially
TGAI Yes
and metabolites
TEP
or PAI
Partially
Hibl lograph i c
Citation
00028728,
00039S11,
00040496,
00040597,
00040605,
00003525,
00134709
00028732
00081610,
00113341 ,
00113357
00081618
Must Ad.) i t i ondl
Data Be Submi t. te.1?
No
Reserved6/
Yes7,8/
T i iitf I i Mine tor
Submission1/
18 Months5'/
18 Months^/
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TABLE A
GENERIC DATA REQUIREMENTS FDR OXAMYI.
Data Requirement
Test Does EPA Bibliographic Must. Additional
Substance Have Data? Citation Data Re Submi11tv
$158.125 Residue Chemistry (cont'd)
171-4 - Magnitude of the Residue - Crop field trials
ON
- Root and tuber
vege '
o Carrots
o Ginger
o Potatoes
TEP Partially
TEP No
TEP, EP Partially
o Sweet potato
- Bulb Vegetables Group14/
o Garlic
o Onion
- Leafy Vegetables Group16/
o Celery TEP
Yes
No
No
Partially
00113339
00040607,
00113339,
00113370
00113339
0037130,
0061648,
0113410,
0147614
Yes10/
Yes11/
Yes'V3/
No
No
Time frame for
Subrai ssion1/
18 Months^/
1B MonthsV
18 Months5,43/
18 Months
18 Months5/
-------
TABU: A
GENERIC DATA HEQUIREMENTS FDR OXAMYL
Data Requirement
Test
Substance
Does EPA
Have Data?
Bibliographic
Citation
$158.125 Residue Chemistry (confd)
171-4 - Magnitude of the Residue (cont'd)
- Crop field trials
- Legume Vegetables Group20/
o Soybeans EP
- Foliage of the Legume
Vegetable Group22/
o Soybean straw
- Fruiting Vegetables Group /
ON
o Eggplant
o Peppers
o Tomatoes
25.
- Cucurbit Vegetables Group__/
o Cantaloupe
o Cucumbers
EP
EP
Partially
Yes
Yes
Yes
TEP, EP Partially
Yes
Yes
00030920
00030920
00081618
00081618,
00113387,
00138996,
00145315
00040603,
00048060,
00084889,
00113419
00143312
00143312
Must Addi 11onal
Data Be Submi tte
-------
TABU: A
GENERIC DATA HEQU I RE MK NTS FOR OXAMYi.
Data
$158
171-
o\
CO
Test Does EPA
Requirement Substance Have Data?
.125 Residue Chemistry (cont'd)
4 - Magnitude of the Residue (cont'd)
- Crop field trials
- Cucurbit Vegetables Group^/
( cont'd )
o Honeydew melon Yes
o Pumpkins EP No
o Summer squash Partially
o Watermelon Yes .
o Winter squash Yes
- Citrus Fruits Group EP, TEP Partially
- Pome Fruits Group30/
o Applts EP Yes
o Pears Partially
- Miscellaneous Commodities
o Bananas EP Partially
11 i hi icxjraphi c Must Additional T i m.j trame for
Citation Data Be Submitted? Submission1/
00143312 No
Yes2f>/ 6 Months
00143312 No£^7
00143312 No
00143312 No
00113343 Yes29,29/ 18 Months^,43/
00067234, No
001 1 3373
00063016 No31/
00113309, Yes_^/ 6 Months
00129354,
001421 26
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR OX AMY I,
Data
$158
171-
Requirement
.125 Residue Chemistry (conf
4 - Magnitude of the Residue
- Crop field trials
Test Does EPA
Substance Have Data?
d)
(cont'd)
Bibliographic Must Additional Timeframe for
Citation Data Be Submitted? Submission1/
- Miscellaneous Commodities (cont'd)
r\
O
o Cottonseed
o Mint
o Peanuts
o Pineapples
o Tobacco
- Nonbearing Fruits
- Meat/Milk/Poultry/Eggs
TEP, EP Partially
EP Yes
TEP Partially
TEP, EP Partially
TEP No
TEP No
Partially
00113341 Yes33,34/ 24 Months5,43/
00126690 No
00083522, Yes3S,36/ 24 Months^, _4_3/
00113357
00113380 Yes37,38/ IB Months5,43/
YesT75,^/ IB Months^, ^/
yes41/ 24 Months5/
00039513, Reserved^/
00040592,
00083524,
001 1 3376
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TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYI,
Footnotes:
§158.125 Residue Chemistry
_»_/ Data must be submitted within the indicated timeframe, based on the date of this Guidance Oocunu.nl.
2/ Refer to Product Chemistry Data Requirement tables.
2/ Studies of the metabolism of (14C)oxamyl in ruminants and poultry. Animals must be dosed for at least 3 days at
a level sufficient to make residue identification and quantification possible. Milk and eggs must he collected
twice daily during the dosing period, and animals must be sacrificed within 24 hours of the final dose. The
distribution and identity of residues must be determined in milk, liver, kidney, muscle, and fat of ruminants,
and in eggs, liver, kidney, muscle, and fat of poultry.
_4/ Samples from studies requested in footnote 3 must be analyzed using current enforcement methods to determine the
usefulness of these methods for analysis of animal commodities.
5/ First Progress Report due 8 months after receipt of this Standard. Interim Reports are due semiannually
therea fter.
6/ If the animal metabolism data required in the section entitled, "Nature of the Residue in Animals" reveal
additional metabolites of toxicological concern or the Toxicology Branch determines that any plant metabolites
must be included in the tolerance definition, additional analytical methods and validation data may be required.
~^J 7/ The storage intervals and conditions of samples used to support all established tolerances for residues must be
O~ submitted. These data must be accompanied by data, depicting the percent decline in residues at the times and
under the conditions specified. (No additional stability studies are required for plant commodities stored
frozen for up to 12 months.) On receipt of 'these data, the adequacy of the aforementioned tolerances will be
reevaluated.
8/ All residue data requested in this Standard must be accompanied by data depicting the duration and conditions
of storage of samples analyzed. These data must be accompanied by data depicting the stability of residues
under the conditions and for the time intervals specified, with the exception of plant commodities stored
frozen for up to 1 2 months. For laboratory tests using fortified samples, the pure active ingredient must b«>
used If field-weathered samples are used, the test substance must be a Ti-P.
-------
TABI.E A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Footnotes:
$158.125 Residue Chemistry (cont'd)
2/ If the registrant wishes to propose a crop group tolerance, use directions must be proposed and residue data
submitted for the additional representative crops radish and sugar beet, in addition to the data r,quired to
support established tolerances for residues in or on carrot and potato.
_HV Data depicting residues of oxarayl in or on carrots following the maximum seasonal treatment regime: the 2 Ib/gal
SC/L or 10\ G formulation preplant incorporated at 8 Ib/ai/A and at-plant in-furrow at 4 Ib/ai/A followed by
three foliar applications of the 2 Ib/gal SC/L made at 2-week intervals at 1 Ib/ai/A. Samples must be collected
at the 14-day PHI. Tests must be conducted in MI. Alternatively, the registrant may elect to cancel this use
permitted under EPA SLN No. MI-820022.
11/ Data depicting residues of oxamyl in or on ginger following separate full-season treatment regimes with the
2 Ib/gal SC/L formulation: (i) a 4 Ib/ai/A preplant incorporated (I'PI) soil treatment followed by two foliar
treatments, the first at 4 weeks postplanting and the second 3 weeks later; and (ii) soil applications at
4 Ib/ai/A by drip irrigation emitters at 1 week postplantinq and repeated at 14-day intervals until 30 days
prior to harvest. Tests must be conducted in HI. The registrant must specify a maximum seasonal rate or
number of appl ica-t i ons for the drip irrigation use which must be reflected in the submitted data.
12/ Data depicting residues of oxamyl in or on potatoes following a full-season treatment tegime, including multiple
foliar applications and soil applications (in-furrow and preplant, in separate tests). The 2 Ib/qal SC/L or
10\ G formulation must be applied in-furrow at 4 Ib/ai/A and, in separate tests, band/broadcast preplant
' incorporated at 8 Ib/ai/A within 1 week of planting. The SC/L must be applied in a volume of at least
20 gal/A. Foliar applications of the 2 Ib/gal SC/L must be made at 1 Ib/ai/A and repeated at S-day intervals.
Samples must be collected 7 days after the final application. The registrant must specify a maximum seasonal
rate or number of applications for foliar treatments which must be reflected in the submitted data. Tests
^ must be conducted in 10(24%), WI(6\). ND(5.7\), O>{5\), and ME(6%) which collectively represented ca. 77%
of 1984 U.S. potato production if ID represents OR(6%) and WA(16%) and WI represents Ml (4%) and HN(4.5%)
(Agricultural Statistics, 1985, p. 164).
'I/ Data depicting residues in wet and in dried potato peels, potato granules, and chips from potatoes bearing
measurable weathered residues of oxamyl. Should residues concentrate in any of these commodities, appropriate
food or feed additive tolerances must be proposed.
-------
TABU: A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Footnotes:
§158.125 Residue Chemistry (cont'd)
14/ If the registrant wishes to propose a crop group tolerance, data depicting residues of oxamyl in or on
the representative group member onion to support the established tolerance must be submitted along with
data depicting oxamyl residues in or on garlic following maximum seasonal use regimes with the 2 Ib/gal SC/L
formulation-. (i) four applications in CA tests at 2 Ib/ai/A, one at-planting in-furrow and three postemergent
treatments via irrigation water (sprinkler or ditch) or as 1- to 2-inch band treatments to the soil surface
at the base of the plant; and (ii) an in-furrow band or drench application at 4 Ib/ai/A followed by three
postemergent bands (6- to 8-inch) or broadcast treatments at the same rate in OR (OR-810033). In OR, samples
must be collected at the 14-day PHI. For CA, the registrant must propose a PHI which must be supported by
the data (EPA SLN No. CA-820068).
IS/ No data are required for garlic because data required for onions (see footnotes 16 and 17) will be translated
— to garlic. It should be noted, however, that translated data may not be used to support a crop group tolerance.
16/ Data depicting oxamyl residues in or on onions following: (i) four applications in CA tests at 2 Ib/ai/A, one
~~ at-Dlantinq in-furrow and three postemergent treatments via irrigation water (sprinkler or ditch) or as 1- to
2-inch band treatments"^ the soil surface at the base of the plant (CA-U2006B); and (ii) an in-furrow band or
drench application at 4 Ib/ai/A followed by three postemergent band (6-8 inch) or broadcast treatments made
at 14-dav intervals at the same rate in OR (OR-810033). In OR, samples must be collected at. the 14-day Pill.
-J For CA the registrant must propose a PHI which must be supported by the data (EPA SLN No. CA-82000U, If the
For LA, tn y support the OR-810033 or CA-820068 label, the MI-840005 label must be supported (one
registrant chooses not to support the « ^emergent applications at 0.25 ib/ai/A at M-day intervals
in-furrow application at 2 Ib/ai/A pi F PU support the MI-840005 label, the ID-830019,
0^^%^^ (multipirpostemerqent applications at 0.25 Ib/ai/A
OR-830025TX 8^0046 and ^^ ^ ^^ con(jucted in IQ and Tx). Tne rt,Jlstrant must
."eel* a* -XV6::: seasonal r.teVnu-b-r of postemergent applications which must be reflected by the data.
. ,-nond the 24(0 labeling for EPA SLN No. NM-810021 to specify an upper limit for treatment
U/ The registrant must *«£ ^. 4(c) 1 * CA-820068 or OR-810033 or the upper limit ,s < 0.25
and submit supporting data <"nle^ ™ J OR-810033 and CA-820068 to include restrictions on harvesting
Ib/ai/A - See(^ttaer9na/tiavberye)i tolerance must be proposed and appropriate supporting residue data submitted
n in or on green onions ,6Sulting from these us,,.,
-------
TABLE A
GENERIC DATA REQUIREMENTS FJR OXAMYL
Footnotes:
§158.125 Residue Chemistry (confd)
_HV If the registrant wishes to propose a crop group tolerance, use directions must be proposed, and appropriate
supporting residue data submitted for additional representative group members 'lettuce and spinach. Also,
additional required data to support the established tolerance for residues of oxamyl in or on the representative
crop group member celery must be submitted.
1 9/ Data reflect -j residues in or on untrimmed celery 14 days after the last of several foliar applications ,11
5-day intervals of the 2 Ib/gal SC/L formulation at 1 Ib/ai/A. Tests must be conducted in I'l. to support S I.N
No. FL-760019, the registered use most likely to result in the highest residues on celery. The fill's for
trimmed celery must be deleted from the label since Agency policy is to set tolerances on and require data
for untrimmed celery. Also, the registrant must specify a maximum number of applications/crop or a maximum
seasonal use rate which must be supported by the data requested above. If the registrant of the t'L-760019
label chooses not to support the FL use, registered uses in MI (MI-820014 and MI-770010) must be supported
with data reflecting residues resulting from a single preplant broadcast application of the 10% G formulation
at 6 Ib/ai/A. The granules should be soil-incorporated to a depth of 4 to 6 inches. Following this preplant
application, three foliar applications of the 2 Ib/gal SC/L formulation at 1 1 b/ai/A/appl i ca t ion must be made
at 2-week intervals to transplanted stock. Samples of untrimmed celery should be harvested 14 days after the
final application. Tests must be conducted in MI. If the registrant does not wish to support the use permitted
under EPA SLN No. MI-820014 but does wish to support use under MI-770010 or PA-800039, the above data are
required from either PA or MI with the exception that the preplant application must be made at 4 Ib/ai/A with
the 2 Ib/gal SC/L formulation.
20/ I f the registrant wishes to propose a crop group tolerance, use directions must be proposed and appropriate
— supporting residue data submitted for the representative group members succulent and dry beans and succulent
and dry peas.
21 / Data depicting residues in grain dust, meal, hulls, soapstock, and crude and refined o,ls processed from soybeans
~ bearing measurable, weathered residues. Should residues concentrate in any of these processed commodities,
appropriate food/feed additive tolerances must be proposed. It may be necessary to apply exaggerated rates
to obtain measurable residues in the raw agricultural commodities.
-------
TABU-; A
GENERIC DATA REQUIREMENTS FOR OXAMVI,
Footnotes:
J158.125 Residue Chemistry (cont'd)
22_/ If the registrant wishes to propose a crop group tolerance, use directions must be proposed and supporting
residue data _, bmitted for the representative group members bean and pea vines and hay.
23/ At present, the registered uses on members of this group are sufficiently different that establishment of a
crop group tolerance is inappropriate.
24/ Data depicting residues in wet and dry pomace, catsup, and juice processed from tomatoes bearing measurable
weathered residues. If residues concentrate in any of these processed commodities, then appropriate food/feed
additive tolerances must be proposed.
25/ If the registrant wishes to propose a crop group tolerance, data depicting oxamyl residues in or on summer
squash harvested 1 day after the last of the following treatments: application of the 2 Ib/gal SC/L or 10% G
formulation at 4 Ib/ai/A as a preplant incorporated broadcast treatment and multiple foliar applications at
.. 7-day intervals of the 2 Ib/gal SC/formulation at 1 Ib/ai/A. Tests must be conducted in CA(15%), PL(21%),
GA(7%), NJ(6\), and TX(7%) which collectively account for 56\ of U.S. acreage in squash and represent the
major geographic regions of squash production (1982 Census of Agriculture, Vol. 1, Part 51, p. 353). Tests
» in CA must include, separately, aerial and ground applications.
26/ There are no registered uses of oxamyl on pumpkins. A registrant must propose a use or the tolerance will be
revoked, th'e proposed use on pumpkins must be identical to the registered use on winter squash as the winter
squash data are used to support the tolerance (2 ppm) for pumpkins. Otherwise, the proposed use on pumpkins
must be accompanied by appropriate residue data to assess the adequacy of the established tolerance.
27/ Although insufficient data are available for summer squash, no additional data are required because the available
— data for cucumber may be translated to support'the established tolerance for residues in/on summer squash. However
it should be noted that translated data may not be used to support a crop group tolerance.
?H/ Data depicting oxamyl residues in or on sweet oranges, lemons, and grapefruits harvested 7 days after the last of
- three foH« treatments at 4 Ib/ai/A. Tests must be conducted in TX to support EPA SLN No. TX-800037. Alterna-
tely, the registrant may elect to cancel EPA SLN No. TX-800037.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Footnotes:
$158.125 Residue Chemistry (cont'd)
29/ Data depicting oxamyl residues in molasses and oil processed from citrus fruits bearing measurable, weathered
residues. Should residues concentrate in any processed product, an appropriate food/feed additive tolerance
muat.be proposed.
30/ If tne registrant wishes to propose a crop group tolerance, data depicting residues of oxamyl in or on pears
harvested 14 days following multiple foliar applications of the 2 Ib/gal SC/L formulation at 2 Ib/ai/A/
application in 100 to 600 gal/A using ground equipment. The registrant must propose a maximum seasonal
rate or number of applications. The required data must reflect this proposal. Tests must be conducted
in WA(29%), NY(3l), and CA(43\); these States produced approximately 75\ of the total 1984 U.S. pear crop
(Agricultural S tatistics, 1985, p. 214). (Although there is presently no registered use in CA, for a crop
group tolerance data would be needed from all geographic production regions.) •
31/ Although insufficient data are available for pears, the available apple data may be translated to support
the established tolerance for residues in/on pears. It should be noted, however, that translated data may
not be used to support a crop group tolerance.
~-^12/ All labels permitting use of oxamyl on bananas grown in countries that export bananas to the United States must
(j"l be submitted and accompanied by English translations. On receipt of these labels, the adequacy of the
established <_3i trance will be reevaluated.
33/ Data from aerial application tests using the 2 Ib/gal SC/L formulation depicting residues of oxamyl in or
— on cottonseed harvested (i) 21 days after the last of four treatments of 1 Ib/ai/A applied in 3 gal water/A
(tests conducted in AZ and CA) ; and (ii) 14 days after the last application of several at 0.25 Ib/ai/A
applied, in separate tests, in 2 gal water/A and 0.375 gal refined vegetable oil/A (tests conducted inTX).
The registrant must amend EPA SLN Nos. TX-840010 and TX-820005 to specify a maximum seasonal rate or number
of applications which must be reflected in the data submitted.
14/ Data from a processing study depicting oxamyl residues in hulls, soapstock, crude oil, and refined oil
nrocessed from cottonseed bearing measurable, weathered residues. Processing procedures, including heating
temperatures and times, must be clearly representative of those in current use for commercial processing.
-------
TABU-: A
GENERIC DATA REQUIREMENTS FOR OXAMYI,
Footnotes:
§158.125 Residue Chemistry (cont*d)
2V Data depicting residues in or on peanut vines and hay harvested after a foliar application of the 2 Ib/gal SC/L
formulation at 1 Ib/ai/A made 6 weeks after emergence and preceded by a foliar application 3 weeks earlier at
the same rate, and an at-plant soil application at 3 Ib/ai/A. Samples must be collected shortly after the second
foliar treatment or at a PHI (hay) and pregrazing interval (vines) to be specified by the registrant. Tests must
be conducted in GA(49\), FL(6%), NC(10\), and TX(8.5\) which together in 1984 produced 74% of peanuts grown in
the United States and account for all major peanut production areas (Agricultural Statistic^, 1985. p. 121).
As an alternative to submission of these data, the registrant may restrict grazing and feeding of vines and hay
and request revocation of these tolerances.
36/ Data depicting residues of oxamyl in the processed products meal, crude and refined oil, and soapstock from
peanuts bearing measurable, weathered residues. Should residues concentrate in any processed product, food/feed
additive tolerances must be proposed.
37/ Data depicting oxamyl residues in or on pineapple forage harvested immediately after the last application of the
following tmtment schedule (using the 2 Ib/gal SC/L formulation): 48 Ib/ai/A cumulative to the plant crop
f< including 8 ll-'ji/A as a broadcast soil application 1 week after planting followed by foliar applications at
4 Ib/ai/A made at 2- to 4-week intervals. Tests must be conducted in HI where ca. 100% of 1982 U.S. pineapples
were produced (1982 Census, of Agriculture, Vol. 1, Part 51, p. 383). Alternatively, the registrant may impose
a 14-day pregrazing restriction.
38/ Data depicting residues of oxamyl in juice processed from pineapples bearing measurable, weathered residues. If
the data indicate potential for residue concentration, a food additive tolerance must be proposed.
39/ Data depicting residues of oxamyl in or on green, freshly harvested tobacco following preplant incorporated (PPI),
~~ transplant water, and two foliar treatments at 6 Ib/ai/A, 0.5 Ib/ai/A, and 1 Ib/ai/A, respectively. Tobacco
plants must be transplanted into treated soil within 1 week of PPI application. Two foliar applications of the
SC/L formulation at 1 Ib/ai/A with a suitable spreader^ sticker must be made to tobacco, the first within 2 weeks
of transplanting and the second 2 to 3 weeks later.
-------
TABU-: A
GENERIC DATA REQUIREMENTS FDR OXAMYI,
Footnotes:
§158.12S Residue Chemistry (cont'd)
40/ If oxamyl residues of _>_ 0.1 ppm are detected in or on green, freshly harvested tobacco, data depicting residues
in or on dried or cured tobacco will be required. If residues in or on dried or cured tobacco tire > 0.1 ppm,
pyrolysis products derived from the active ingredient must be characterized and the level of the residue in smoke
must be quantified. (('^ClOxamyl must be used for identification of pyrolysis products.)
41/ Data depicting residues of oxamyl in or on fruit from cherry, peach, or pi urn trees and si iwberry plants treated
with the 10\ G formulation at 20 Ib/ai/A postplant and at 2 lb/ai/200 cjal/A with a spreader sticker in foliar
applications. Fruit must be harvested 1 year following the last treatment. Should residues be detected in or
on fruit following oxamyl treatment in a nonbearing year, tolerances must be proposed.
42/ Presently, the nature of the residue in animals is not adequately understood. On receipt of the requested animal
metabolism studies, the need for the nature of tolerances for residues in animal commodities will be determined
and the need for additional feeding studies evaluated.
43/ The timeframe for the submission of processing studies is 24 months.
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING OXAMYL
Data Requirement
Test
Substance
58.120 Product Chemistry
'roduct Identity and Composition
61-1 - Product Identity and Dis-
closure of Ingredients
61-2 - Description of Beginning
Materials and Manufacturing'
Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of
Product Ingredients
62-1 - Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Methods to Verify
Certified Limit
>
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
MP
MP
MP
MP
MP
MP
MP
MP
MP
Does EPA Bibliographic
Have Data?!/ Citation I/
Must Additional Timeframe
Data be for
Submitted? Submission2/
Yes
Yes
Yes
Yes
Yes
Yes
6 months
6 Months
6 Months
Yes
Yes
Yes
12 Months
12 Months
12 Months
6 Months
6 Months
6 Months
oo
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING OXAMYL
vO
Data Requirement Test Does EPA Bibliographic Must Additional Timeframe
Substance Have Data?!/ Citation I/ Data be for
Submitted? Submit inn?/
158.120
Physica
(contl
63-7
63-12
63-14
63-15
63-16
63-17
63-18
63-19
63-20
Product Chemistry (continued)
1 and Chemical Characteristics
nued)
- Density, Bulk Density, or
Specific Gravity
- pH
- Oxidizing or Reducing
Ac v :' on
- Flammability
- Explodabil i ty
- Storage Stability
- Viscosity
- Miscibility
- Corrosion Characteristics
MP
MP
MP
MP
MP
MP
MP
MP
MP
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
6 Months
6 Months
6 Months
6 Months
6 Months
15 Months
6 Months
6 Months
15 Months
I/ Although product chemistry data may have been submitted in the past, the Agency has determined that these data must
be resubmitted for each manufacturing-use product. New requirements have been introduced and previously submitted
data must be updated. Therefore, bibliographic citations for the old data are not applicable.
21 Due dates refer to the number of months following receipt of this Registration Standard by the registrant, unless
otherwise indicated. .
3/ Formulation intermediates are also included in the category of manufacturing-use products.
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING OXAMYL
)ata
Requirement Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data? Citation Data be for
Submitted? Submlsslonl
158.135 Toxicology
*CUTE TESTING:
31-1
U-2
91-3
91-4
91-5
31-6
- Acute Oral Toxlclty - Rat
- Acute Dermal Tt~ic1ty -
Rabbit
- Acute Inhalation Toxlclty -
Rat
- Eye Irritation-Rabbit
- Dermal Irritation-Rabbit
- Dermal Sensl tlzatlon-
Gulnea Pig
«
HP
MP
MP
MP
MP
MP
ABEF No
ABEF No
ABEF No
ABEF No
ABEF No
ABEF No
Yes 9 Months
Yes 9 Months
Yes 9 Months
Yes 9 Months
Yes 9 Months
Yes 9 Months
I/ Due *ttt refer to the nu-ber of •*«» f.ll«rl«« receipt of this Registration Standard by the re9istrant, unless
otherwise Indicated.
oo
o
-------
TABLE C
PRODUCT SPECIFIC DATA REQUIREMENTS FOR END-USE PRODUCTS CONTAINING OXAMYL
Guideline Citation and Name of Test
Test Use Does EPA Bibliographic Must Addi tional Timeframe
Substance Patterns Have Data?!/ Citationl/ Data be for
Submission?/
158.120 - Product Chemistry
Product Identity:
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Materials
and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
62-1 - Certification of Limits
62-3 - Analytical Methods to Verify
Certified Limit
>hys1cal and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
-- -. n ft-., DnlL noncitv. or
EP
EP
EP
EP
EP
EP
EP
EP
EP
EP
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
juuiui nei
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Jf 5UD
6 Months
6 Months
6 Months
12 Months
6 Months
6 Months
6 Months
6 Months
6 Months
6 Months
"specific Gravity
CO
-------
TABLE C
PRODUCT SPECIFIC DATA REQUIREMENTS FOR END-USE PRODUCTS CONTAINING OXAMYL
Guideline Citation and Name of Test
Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data?!/ dtationl/ Data be for
158.120 - Product Chemistry (continued)
Physical and Chemical Characteristics^
63-12 - pH
63-14 - Oxidizing or Reducing
Action
63-15 - Flammablllty
63-16 - Explodablllty
63-17 - Storage Stability
00&3-18 - Viscosity
63-19 - Mlsclblllty
63-20 - Corrosion Characteristics
63-21 - Dielectric F -nkdown Voltage
Other Requirements:
64-1 Submlttal of Samples EP.TGAI
ontini
EP
EP
EP
EP
EP
EP
EP
EP
EP
,PAI
have
ued)
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
Teen submitted in the pc
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Reserved3/
ist, the Agency has determined
JUUIIII ib 1 Ullil/
6 Months
6 Months
6 Months
6 Months
12 Months
6 Months
6 Months
6 Months
6 Months
that these data musi
I/ Al
3/
tted for each pestlcl
. .....
them-
-------
TABLE C
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158. 135 Toxicology
ACUTE TESTING:
81-1 - Apute Oral Toxicity - Rat
81-2 - Acute Dermal Toxicity -
Test
Substance
10G
10G
Use
Patterns
ABEFHI
ABEFHI
Does EPA
Have Data?
No
No
Bibliographic Must Addi
Citation Data be
Submitted?
Yesl
Yesl
tional Time frame
for
Submission
9 Months
9 Months
Rabbit
81-3 - Acute Inhalation Toxicity -
Rat
10G
ABEFHI
No
Yes
9 Months
I/ These data are required only if the Toxicity Category I and Restricted Use Classification are challenged by the
registrant. These data will be waived if the registrant elects to restrict the product and utilize Toxicity
Category I labeling.
CD
-------
APPENDIX II
LABELING APPENDICES
84
-------
LABEL CONTENTS
40 CFR 162.10 requires that certain specific labeling statements
appear at certain locations on the label. This is referred to as
format labeling. Specific label items listed below are keyed to the
table at tne end of this Appendix.
Item 1. PRODUCT NAME - The name, brand or trademark is required
to be located on the front panel, preferably centered in the upper
part of the panel. The name of a product will not be accepted if it
is false or misleading. " ,
Item 2. COMPANY NAME AND ADDRESS - The name and address of the
registrant or distributor is required on the label. .The name and
address should preferably be located at the bottom of the front panel
or at the end of the label text.
Item 3. NET CONTENTS - A net contents statement is required on
all labels or on the container of the pesticide. The preferred
location is the bottom of the front panel immediately above the
company name and address, or at the end of the label text. The net
contents must be expressed in the largest suitable unit, e.g., "1
pound 10 ounces" rather than "26 ounces." In addition to English
units, net contents may be expres'sed in metric units. [40 CFR
162.10(d)]
Item 4. EPA REGISTRATION NUMBER - The registration number
assigned to the pesticide product must appear on the label, preceded
by the phrase "EPA Registration No.," or "EPA Reg. No." The
registration number must be set in type of a size and style similar to
other print on that part of the label on which it appears and must run
parallel to it. The registration number and the required identifying
phrase must not appear in such a manner as to suggest -or imply
recommendation or endorsement of the product by the Agency. [40 CFR
162.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment number,
preceded by the phrase "EPA Est." 1s the final establishment at which
the product was produced, and may appear in any suitable location on
the label or immediate container. It must also appear on the wrapper
or outside container of the package if the EPA establishment number on
the immediate container cannot be clearly read through* such wrapper or
container. [40 CFR 162.10(f)]
Item 6A. INGREDIENTS STATEMENT - An ingredients statement is
required on the front panel. The ingredients statement must contain
the name and percentage v weight of each active ingredient and the
total percentage by we jnt of all inert ingredients. The preferred
location is immediately below the product name. The ingredients
statement must run parallel with, and be clearly distinguished from,
other text on the panel. It must not be placed in the body of other
text. [40 CFR 162.10(g)]
85
-------
Item 68. POUNDS PER GALLON STATEMENT - For liquid agricultural
formulations, the pounds per gallon of active ingredient must be
indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY 'STATEMENTS - Front panel
precautionary statements must be grouped together, preferably within a
block outline. The table below shows the minimum type size
requirements for various size labels.
Size of Label Signal Word "Keep Out of Reach
on Front Panel Minimum Type Size of Children"
in Square Inches All Capitals Minimum Type Size
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - The statement
KEEP OUT OF REACH OF CHILDREN must be located on the front panel
above the signal word except where contact with children during
distribution or use is unlikely. [40 CFR 162.10(h)(l ) (ii)]
Item 7B. SIGNAL WORD - The signal word (DANGER, WARNING, or
CAUTION) is required on the front panel immediately below the child
hazard warning statement. [40 CFR 162.10 (h)(l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, dermal, or
inhalation toxicity. the word "Poison" shall appear on the label in
red on a background of distinctly contrasting color and the skull 'and
crossbones shall appear in immediate proximity to the word POISON.
[40 CFR 162.10(h)(l)(i)]
Item 7D. STATEMENT OF PRACTICAL TREATMENT - A statement of
practical treatment (first aid or other) shall appear on the label of
pesticide products 1n toxicity Categories I, II, and III. [40 CFR
162.10(h)(l)(111)]
Item 7E. REFERRAL STATEMENT - The statement "See Side(or Back)
Panel for Additional Precautionary Statements" is required on the
front panel for all products, unless all required precautionary
statements appear on the front panel. [40 CFR 162.10(h)(l )(iii)]
Item 8. STn.E/BACK PANEL PRECAUTIONARY LABELING - The
precautionary sta* •...•ents listed below must appear together on the
label under the heading "PRECAUTIONARY STATEMENTS." The preferred
location is at the top of the side or back panel preceding the
directions for use, and it is preferred that these statements be
surrounded by a block outline. Each of the three hazard warning
statements must be headed by the appropriate hazard title. [40 CFR
162.10(h)(2)J.
86
-------
Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a hazard
exists to humans or domestic animals, precautionary statements are
required indicating the particular hazard, the route(s) of exposure
and the precautions to be taken to avoid accident, injury or damage.
[40 CFR 162.10(h)(2)(i )]
Item 8B. ENVIRONMENTAL HAZARD - Where a hazard exists to non-
target organisms excluding humans and domestic animals, precautionary
statements are required stating the nature of the hazard and the
appropriate precautions to avoid potential accident, injury, or
damage. [40 CFR 162.10(h )(2)(ii )]
Item 8C. PHYSICAL OR CHEMICAL HAZARD - FLAMMABILITY
Precautionary statements relating to f1ammabi1ity of a product are
required to appear on the label if it meets the criteria in the"
PHYS/CHEM Labeling Appendix. The requirement is based on the results
of the flashpoint determinations and flame extension tests required to
be submitted for all products. These statements are to be located in
the side/back panel precautionary statements section, preceded by the
heading "Physical/Chemical Hazards." Note that no signal word is used
in conjunction with the f 1 armabi 1 i ty statements.
Item 9A. RESTRICTED USE CLASSIFICATION - FIFRA sec. 3(d) requires
that all pesticide formulations/uses be cl assi f ied-for either general
or restricted use. Products classified for restricted use -may be
limited to use by certified applicators or persons under their direct
supervision (or may be subject to other restrictions that may be
imposed by regulation).
In the Registration Standard, the Agency has (1) indicated certain
formulations/uses are to be restricted (Section IV indicates why the
product has been classified for restricted use); or (2) reserved any
classification decision until appropriate data are submitted.
The Regulatory Position and Rationale states whether products
containing this active ingredient are classified for restricted use.
If they are restricted the draft label(s) submitted to the Agency as
part of your application must reflect this determination (see below).
If you do not believe that your product should be classified for
restricted use, you must submit any information and rationale with
your application for reregistrati on. During the Agency's review of
your application, your proposed classification determination will be
evaluated 1n accordance with the provisions of 40 CFR 162.11(c). You
will be notified of the Agency's classification decision.
87
-------
Classification Labeling Requirements
If your product has been classified for restricted use, the
following label requirements apply:
1. All uses restricted.
a. The statement "Restricted Use Pesticide" must
appear at the top of the front panel of the label. The
statement must be set in type of the same minimum size
as required for human hazard signal word (see table in 40
CFR 162.10(h)(l)(iv)
b. Directly below this statement on the front panel,
a summary statement of the terms of restriction must
appear (including the reasons for restriction if specified
in Section I). If use is restricted to certified applicators,
the following statement is required: "For retail sale
to and use only by Certified Applicators or persons
under their direct supervision and only for those uses
covered by the Certified Applicator's Certification."
2. Some but not all uses restricted. If the Regulatory
Position and Rationale states that some uses are classified
for restricted use, and some are unclassified, several courses
of action are available:
a. You may label the product for Restricted use.
If you do so, you may include on the label uses that
are unrestricted, but you may not distinguish them
on the label as being unrestricted.
b. You may delete all restricted uses from your
label and submit draft labeling bearing only unrestricted
uses.
c. You may "split" your registration, i.e., register
two separate products with identical formulations, one
bearing only unrestricted uses, and the other bearing
restricted uses. To do so, submit two applications for
reregistrati on, each containing all forms and necessary
labels. Botti applications should be submitted simul-
taneously. Note that the products will be assigned
separate registration numbers.
Item 98. MISUSE STATEMENT - All products must bear the misuse
statement, "It is a violation of Federal law to use this product in a
manner inconsistent with its labeling." This statement appears at the
beginning of the directions for use, directly beneath the heading of
that section.
88
-------
Item 10A. REENTRY STATEMENT - If a reentry interval has been
established by the Agency, it must be included on the label.
Additional worker protection statements may be required in accordance
with PR Notice 83-2, March 29, 1983.
Item 108. STORAGE AND DISPOSAL BLOCK - All labels are required
to bear storage and disposal statements. These statements are
developed for specific containers, sizes, and chemical content. These
instructions must be grouped and appear under the heading "Storage and
Disposal" in the directions for use. This heading must be set in the
same type sizes as required for the child hazard warning. -Refer to
Appendix II, STOR, PEST/DIS, and CONT/DIS to determine the storage and
disposal instructions appropriate for your products.
Item IOC. DIRECTIONS FOR USE - Directions for use must be stated
in terms which can be easily read and understood by the average person
likely to use or to supervise the use of the pesticide. When
followed, directions must be adequate to protect the public from fraud
and from personal injury and to prevent unreasonable adverse effects
on the environment. [40 CFR 162.10]
COLLATERAL LABELING
Bulletins, leaflets, circulars, brochures, data sheets, flyers, or
other written or graphic printed matter which is referred to on the
label or which is to accompany the product are termed collateral
labeling. Such labeling may not bear claims or representations that
differ in substance from those accepted in connection with
registration of the product. It should be made part of the response
to this notice and submitted for review.
89
-------
O
SUMMARY-6
LABELING REQUIREMENTS OF THE FIFRA, AS AMENDED
lEM
1
7
3
4
b
;A
>B
7
'A
^
LABEL ELEMENT
Product name
Company name
and address
Net contents
EPA Reg. No.
EPA Fst. No.
Ingredients
statement
Pounds/gal ion
statement
F ront panel ""*
precautionary
s i a iciucii Li ^^__^
Keep uut of Reach
of Children
(Child hazard
warning) _t
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
AIT products
AIT products
Liquid products
where dosage
given as Ibs.
ai/unit area
All products
11 n rf\(\l\C f Q
All products
PLACEMENT
REQUIRED
Front panel
None
None
None
None
FVont panel '
•ront panel
Front panel
Front panel
^ Front panel
ON LABEL
PREFERRED
Center front
pane)
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel ,
immediately
before or
fol lowing
Reg. No.
Immediately
following
product name
nrectly below
the main
ingredients
statement
Above signal
word
Immediately
below child
hazard
warning
COMMENTS
Tf registrant is not the producer, must
be qualified by "Packed for . . ..'
"Distributed by. . .," etc.
May be in metric units in addition to
U.S. units
Must be in similar type size and run
parallel to other type.
May appear on the container instead of
the label.
ext must run parallel with other text
on the panel .
All front panel precautionary statements
must be grouped together, preferably
blocked.
Note type size requirements.
Note type size requirements.
-------
SUMMARY-7
J
vO
\
i
i
LAbtL LLtMLNI
bKui I & cross-
bones and word
POISON (in red)
Statement of '
Practical
Treatment or
First Aid
Referral
statement
Side/back panel
precautionary
statements
' Hazards to
humans and
domestic
animals
~Tnvi ronmenta 1
hazards
•
APPLICABILITY
OF REQUIREMENT
AI i products
which are Cat-
egory I based
on oral , der-
mal , or inhala-
tion toxlclty
1 All products
in Categories
I, II. and III
All products
where pre-
cautionary
label ing
appears on
other than
front panel .
All products
All products
in Categories
I, II. and III
TTTl products
• —
PLACEMENT
HLIJU1HLD
l-ront panel
1 Category I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped wi th
side panel
precauti onary
statements.
Front panel
None
None
None
• •
UN LAULL
PKLI-LRRED
Both in close
proximity to
signal word
Front panel
for all .
Top or side
of back panel
preceding
di recti ons
for use
Same as above
Same as above
i —
COMMENTS
Must be grouped under the Headings in
8A, 8B. and 8C; preferably blocked.
Must be preceded by appropriate signal
word.
Environmental hazards include Dee
caution where applicable.
-------
SUMMARY-8
rr u
1 LM
IL
JA
9B
IUA
IUB
roc—
LABLL ELEMENI
*nysical or
chemical
hazards
Restricted
block
Misuse
statement
Reentry
statement
Storage and
disposal block
Directions
for use
1 APPLICABILITY
OF REQUIREMENT
All pressurized
products, others
with flash
points under
150~F
All restricted
products
All products
*
PR Notice 83-Z
or as determined
by the Agency
All products
All products
1 PLACEMENT
REQUIRED
None
Top center
of front
panel
Immediately
following
heading of
directions
for use
In the
directions
for use
In the '
directions
for use
None
ON LABEL
PHLhERRED
Same as above
Preferably
blocked
Immediately
after misuse
statement
Immediately
before
specific
directions
for use or
at the end of
directions
for use
None
COMMENTS
Refer to Appendix II guide
PHYS/CHEM
Includes a statement of the terms of
restriction. The words "RESTRICTED USE
PESTICIDE" must be same type size as
signal word.
Required statement is:
"It is a violation of Federal law
to use this product in a manner
inconsistent with its labeling."
Must be set apart and clearly distin-
guishable from from other directions
for use.
Refer to Appendix II guides STOR,
CONT/DIS, and PEST/DIS for further
information and required statements.
May be in metric as well as U.S. units
-------
P*t CAUTION AMY (TAIEMCN7B
HAXAA04 TO HUMANS
|1 DOUESTC
ENVMXUf MTAL KAZAN*
pwr*c,v O
HA2AAM
Kf-CMTKY fTATf UlNl
STORAGE AND
' DISPOSAL
RESTRICTED USE
PESTICIDE
(jreaaon for clnsnlfylnr)
ICtAIL S*J TO AWD LBt CKLI IT CWTlna) WfTICATOKi OK
« «MDCX IMtU 01MCT iUPnrvuiON MO ONLf fC« HCbE
OVOW) IT THE CZXTIMtO AmjCATWi CtKTlfJCATICW
PRODUCT
NAME
ACTIVE NOHEOCNT:
HIK1 NOACMNT*
TOTAL:
100 00 \
Txa rnoovxi COHTAMJ LM or fEN cuuow
KEEP OUT OF REACH OF CHILDREN
DANGER —POISON
•TATIUCNT Of ffUCTCAt. THfATUINT
M IYIS
Ml U)ff PANEL fOU AOOmOMAL PMCAUDONXNV 9TAUUENTS
UFO ir:
TOWN. >TATI
IJTAKJJMUINT NO =
If A RCOOTnATION NO
NET CONTENTS:
CHOP:
CttOf:
cnor.
ChOf.
WAfWANTY fTATOOKT
-------
(1AUMIK1*
HAIAItt* TO HUUAJU
* OOMEfTC ANMAU
CAUTION
^", A4. HATAMM
HA2AMM
I • •
* •
9U-CMTHV 9TATIMCMT
one*-..
PRODUCT
NAME
ACTNt MOflCOOtt:
MOAUXMT*
IOIAU
10000%
TM» PRODUCT COMTAMS LM Of n* OAU.OM
KEEP OUT OF REACH OF CHILDREN
CAUTION
fTATCUINT Of PHACnCAL TRCATU£NT
» MHAUO
r ON »KMI
f N It It
•ci tot f Awet ro* AOomoMAi
ITATIUEMU
TOWN. ITATI ;
UTAIUSHUtMT NO. =
(FA ftf (MIRATION MX :
NCT CONTENT*:
CAOT:
CAOT:
CHOP:
STORAGE AND
DISPOSAL
•10/1x01 =
WAIWAMIYITATUICNT
-------
it obtained Us* 4tn from moth?
(idfodtyr, aooUcant copied
» publication: applicant oat
37 or th* data tram EPA).
Tn* applicant «*«n submit
ppUcutloa i stAtoncnt that
^er*lu*aoQ or th* prop«ru«
iaad taTrcy or th* formv
?nd-ua* product. ™«r QOC cotm
niDportln*
ezcep< \.h* foUovtn* <
(1) TO* data
mltt*d t\ EPA nm-Uf p*r»4Ta£a (b) or
thu »*ca
(3) OtHfcr ^«>« p*rtalni£c to
aJrty or fc* product'i act
enu. r»th*k. than to th* i^frty or tii*
end-u** p
(3) »^Tl»^n^ tolcmaea. /ood
tztmpUonj/ iad other
cl
Tood. Onic. idy Cocmei^c Act.
(•) U en* tci
lUm of d*t*
McCoa v«j n
P«DM or) 1QO<
ly submitted tho'
pr^dtcesaor. U3O^
for rtdnrvooo.
p«rmlt. or inw
OM to &a *i
n >>»•> my
andrr tiu
37 (or u th* tz-
to EPA (or !U
'oa or i/ter Jinu-
in iflpilcaUon
rvAcn*d vrlt
xmount ud :$• :ermj
407 came
tbl* und«
J(cxixDxu)/witn
or the tppii'Lt'KA S*cQon 3(cKl) of t
product .rith cotnpoeiuon mdVnund-
•di«j/dentlcal to tho«* propoaed (or
•pUcant'i product. undeJy. th*
lenu In etfect oo\Ui*
dat*/EPA approTc* th* appllca^fi
prt**xu application.
24CL j. t. '"^ U
0-1C 114 it M«.)
rv« rn n»ii MA/
FTTRA. u
11. irrti
I 1IZ.19 Lt*«ltn« n^ulrtm«iiu.
(»J GrarraJ — (1) C&ntmU o/
Uo«t Crvrr p«*ttdd« producu
cioa ip*dlled by th« Act ind <_h«
'.iuooj ji thli PVTL The «nunu 3f t
1*0*1 muit ino« cl**/Ly md promi-
nently in* follovuic:
M) The aim*, onnd. or U-idcsuurt
'in'I^T wruch t_ne product J told u prt-
>cnb*d la P*TMTVO& «6) or Uui v*c-
uoa:
iU) Th* nun* md iddrca of '.ft*
producer. r*TUtrvnt or p*rson for
wQom produced u presented la ;«JT^-
cnpa (. o of taai Mcaoa:
(Ul) T.i act connjiu u prtv3-.!>*d
j of '-tui
95
-------
| 142.10
(Iv) The product registration
number a* prescribed In paragraph (e>
ol Ihla section;
(v> The producing aatabtlahment
number a* prescribed In paragraph (f)
ol thta arctlon;
4*1) An Ingredient statement M pr»-
arrlbed In paragraph <•> ol this aec-
Uon;
Ivll) Warning or precautionary state-
anenU aa prescribed In paragraph
ol Ihla aecllon;
<*llll The direction* for usw a* prw-
•crlbed In paragraph II) ol Ihte aecUon:
and
(U> The taat elaaaffleaUortfa) M pra-
actlbcd In paragraph ()> ol thta section.
(1) rromUeMce aitsT lerlMJIfa. (I) AH
worda. •laUmenla. graphic rrpreaenla-
Uona. dealgna or other Information re-
quired on the labeling bjr UM Act or
the regulation* In Into part mart b*
clearly Will hie to a petaon with normal
vUkm, and must be placed with guch
cotmplcttoiigixaa (M compered with
other word*. •lalrmenta, designs, or
graphic matter on th« Ubellrtf) and
expressed In mich tern. * to render It
likely lo be re«4 and _/»derstood by
the ordinary Individual under custom-
ary conditions of purchase and uae.
(II) All required label te«t mual:
(A) Be art In ••point or tarter type".
(B) Appear on a clear conlragUng
background; and
Hot he obacured or tio»dod.
IJ) L+*ru**e to 6e tued. All required
Ubcl or labclln« lei I snail appear In
In* Khgilah rancuagr However. th«
Airencr may require or UM applicant
may pvopoat additional Uit In other
language* M fa cona+dered neoaaaary to
protect the public. When additional
leit In another language to neceawary.
•II labeling retiulremenU win be ap-
plied equally to both the English and
other language veralorsi of lh« label-
In*.
14) naremmf o/ L«o«i-4h Otntr+L
The label shall appear on or b« aecure-
|y attached to the Immediate contain-
er of the poattcM* product, for pur
poaea of thta Section, and UM mta-
brandmg provtolona of the Act, "se-
curely attached" shall mean that a
label «u» r«wonably be r«p«eU>d U»
rrmkln •lllm«4 <«uftn« th* loif»««»b>«>
TlrU 40—rr*l*ctl»«i «f
wrapper or ouUrtde container through
which the label cannot be clearly read.
Ihe label muat atao be securely at-
tached lo guch oulatde wrapper or con-
Ulner. If It • a part of Ihe package a*
cuatomarlly distributed or sold.
(Ill Tank car* ana* offr bmtk eon-
fafner*— Anr
Oovrrn
or devlccr.
or Indl-
any agency ol the
ment;
(•I) The name ol a pmttaMe which
contain* I wo or more principal actlte
ln«rrdlrnt« If (he narnr Ku««rnU one
or more bill not all such principal
active InnrrdlrnU even lhou«h the
nurnr* ol Ihr other Ingrrdlrntn «rr
KUted rlwrvhrrr In the Ubrlln*:
(*lll A (rue xlolrmrnt iinrd In Much a
way a* U> »l»e » lulur or ml'lrt toxic rhrml
caU known"
«C> •Tolhillon approved"
(•) Final prlnlrd tabrltny (I) Excepl
a* provided In paragraph (aM6Nll) of
thta arctkm. final printed labeling
itiuxt br gubmlttcd and arcrptrd prior
lo regbrtratlon. However, final printed
labeling nr*d not be aubmlltpd unlit
draft label lr*U have been provision-
ally accepted by the Agency.
(II) Clearly legible reproduction* or
photo reduction* will be accepted for
untwual label* *uch a* thone *llk-
it.ie>iKd directly onto gla** or metal
container* or large bag or drum labels.
auch reproduction* mu*t be of micro-
film reproduction quality.
(b) Hamf. brand, or trattrmarlt. (I)
The name, brand, or trademark under
whkh Ihe pentlclde product In sold
iihall apnear on the front panel of (he
label
(3) No name, brand, or trademark
may appe*r on the litbcl which:
(I) In (nine or mlnlemllna. or
(II) 1 1 a* nol been approved by the
Administrator tliroimh rr«l«lr»llon or
•
5 Ul 10
(c) Name and addrm ol producer.
registrant, or person lor whom pio
dured An unqualified namr nod »d
drr-w given on Ihr laln-l ulinll br ron
sldered a* Ihe numr mid addre*a of Ihr
producer. II Ihr rrglalranl n namr up
pear* on the Uhrl »nd the rrsHlrnul In
nol the producer, or II (he nnmr ol Ihr
person lor vhom Ihe prsllrldr won
prodtK-rd *ppenrr< on Ihr lahel. II mu-/<>
durer.
Id) Hrt tprloht or mri«nrr o/ ron
If nit (I) The nrl weight or mrimmr
of content »h*ll he enchi^lvr ol *rni>
per* or other motrrliOi and nh»ll br
Ihr airrraiie conlrnl unlrni rupllrllly
slated M a minimum qtinnllly.
(7> II the pcflllrldr I* a liquid Ihr
net content nlalrmrnl shall hr In
(ermed In metric unit*.
(•) Varlallon above minimum eon
lenl or around an average la permlwl
ble only lo Ihe exlenl thai II rrprr
sent* deflation unavoidable In good
manufacturing practice Vnrlnllon
below a staled minimum I* nol permll
ted. In no ca*e shall Ihe average ron
lent of the packages In a shlpmrnl (nil
below Ihe slaled arerane content.
(e) Product rrpiilrallnn numhrr
The reglstrallon numher a*.*lgnrd lo
the pesticide product at the lime of
registration shall appear on the Inhrl.
preceded by the phra.*e "r7fM nr«N
tration No.." or the phr«-*r "FPA (!«•«
Ho " The reglntrollon numrwr xlmll ttr
•rt In type or • flfr »nd olylr xlmli*r in
-------
I !»*..•
to 1C The rcfftaUmUon number
UM required idenUlyin* phraae
ahaJI not appear hi *oeh a manner u
U »umM or Umply recommendation
or endorse meitt of the product by UM
A««ncy.
• •mber. The producto*
Ibhment redatrallon number preced-
ed by lh« phraae "KPA •«*.". of UM
final eetAbibhment at which UM prod-
uct WM produced may appear In any
•ullabie location on the label or hmmt
dlaU onnUJner. It must appear on UM
wrapper or ouUkfa container ol UM
package If the KPA e*Ublbhm«nt reg-
istration number on the ImmsJUU
container cannot be dearly
through such wrapper or container.
- -
el The label of each peatidd* product
must bear a •Utemenl which contain*
Lh« name and percentage by weight of
each active Ingredient, the total per-
oenlage by weight of all Inert ln«rtxM-
enU: and If the pesticide contain* ar-
senic In any form, a statement of th«
percentages of total and water -voluble
arsenic calculated as ekmenlal ar-
•enle. The active Ingredients must be
designated by the term "active Ingredi-
ents" and the Inert Ingredients by the
term "Inert IngredlenU." or the slngu-
lar forms of thes* terms when appro-
priate. Roth term* shall be In the
same type (toe. be aliened to the came
margin and be equally prominent Ttve
statement "Inert Ingredients, none" I*
not required for pesticide* which con-
tain IM percent active Ingredients.
Union the Ingredient statement b a
complete analysis of the pe*Udde. U»e
term "analysis" shall not be uaed as a
neadlnc for th« Incredlent (tatement.
«1) fofitlom oj infrtdUnl $UUm*nL
(I) The Ingredient etaUmenl I* nor-
mally required on the front panel of
the Ubrl. If ther ., an ouUlde con-
tainer or wrapper />vu«h which Ine
Inrredlent •UOemenl cannot be clearly
read, the Inaredlent vUlenkent mu«t
kteo appear on «uch ouUlde container
or wrapper. If U>e «tae or form of U»e
p»ck*«e make* It Impracticable to
pUce the ln«redlenl ctatement on the
rrool panel of the label, perrotarion
may be (ir«jiU>d for the Incredlenl
rUUmenl to appear etoewhere.
TKU
» ->«^ rw« parallel with other
Umt on UM panel on which M. appeara,
and muwl be dearly dMIncukhable
from and muwl not be placed In the
body of other text
<1) Name* to be »Mrf U im*r*dUnt
ttaUmenl. The name woed for each bv
•redlent ahall be UM accepted
common name. If there h one. fol-
lownt by UM chemical name. The
commort name may be imtd alone only
U It b well known. If no wimmon name
ha« been eMabttahed. the chemical
name alone aball be UM>d. In no can
wtU the UM •* a trademark or propri-
etary name be permitted unlcm «uch
ha« been accepted a* a common
name by UM AdmJnbtralor vnder the
authority of Section »l«iUncanUy.
the product murt bear the following
•tatement wt a prominent porilion on
the label: "Hot for mie or UK alter
(date)."
(II) The product mimt meet all label
claim* up to the expiration lime IndJ
catcd on the UbeL
<7> Imfrt i**Tf4tr*U. The Admlrsta
tralor may require the nao*e of any
•I rVe4*ctte«
Inert ln«redlenU*> to be Ibied In the
Ingredient •Utement If he determine*
that auch IncredlenUi) may poae a
hjLxard to nuui or thr environment.
(h) Wmmlmfft u*4 »rece>floa«r|r
it*tfwif»Li. Required wamlnm and
precautionary •tatemenU concernlnf
the grneral area* of toxlcolocloal
hazard Includlrwi hazard to children,
environmental hazard, and phymical or
chemical hazard fall Into two troop*;
thoee required on the front panel of
the labrllnc and thow which may
9
appear cbewhere. 8prririr i
menU ooinccmlnc content. pUornvi
type atee. and promlnmrr »rr «l*
below.
(I) Kf^ulrnd front p**H iltlrmrn
With the exception of Uir clil
hazard wamlnc •tatrmrnt. Ihr lr»( i
quired on the front fux*! of Ihr Uti
b determined by UK ToiMly Cnlrii
ry of the peoUdde. Tli^ r»lr«ory U •
tlgnaS on the b«*b of Uir lilnlir
hazard chown by any of irw Imltotln
In the Uble below-.
(I) Humun limJtrd ilffmal loonf—
Toiicilf Category I. All pesticide prod-
uct! nveeUni the criteria of Toxldty
Catefory I ahall bear on the front
panel the dmal word "Dancer." In ad-
dition If the product wa* amlfned to
ToikUy Category I on the bad* of IU
oral. Inhalation or dermal toxldty (a*
dbllnct from akin and eye local ef-
fecU) the word "Pobon" shall appear
In rrd on a background of dbllnctly
conlnuitln« color and the ukull and
crombofMii chall appear In Inunedlate
proximity to lh« word "poi*on.~
(HI TarlcHw Cuttyorv II. All peatl-
cMe product! meeting the criteria of
ToxvcUy CaUgory II chall bear on the
front panel the ilgnal word "Warn-
ing "
(C> ToHcl/r C*Uyont III. All pertl-
cMe product! meeting the criteria of
Toxklty Category HI ihall bear on
the front (wuml the ilgnal word "Cau-
tkjn "
(U) ToiMtr Ctleyor* IV. All peeti-
ckV prodixrU meeting the criteria of
Toik-lly CiUgory IV ihall bear on the
front panel the iUgn«l word "Caution."
(E) Vtf of il(naj iponli. Umt of any
-|«iij>l worcMi) uotodaled with a hUher
Toxldly Category b not primllUxi
except when the Agency drU-rmlnr*
that cuch labeling b nrrtmty to prr
vent unreasonable advrrw rffrcU on
rn«n or the envlrorunrnL -In no nuie
•hall more than one human huwrd
•ignal word appear on the front porwl
of a UbeL
(II) OiU AaMrrf wmnftmf Rvrry pr»
Uc*de product label ihall bmr on the
front panel the *i«ly
the applicant to be cxtrrmrly rrmotr.
or If the nature of the pe>tlcin thr front
panel of the label of all prattcMm mil
big hi to ToMWljr Calrwory I on thr
bub of oral. Uihalatlon or dermal U»
Idly. The Agency nu>y. ho*r*rr.
prrmvlt reaaonabie varUiUona In Ihr
of th« «4jil«-in«^i( ol i.i«ril
-------
CO
| 10.10
c»l treatment I* acme reference tueh
as "Bee statement of practical treat-
ment on beck panel" appear* on the
front panel nea/ the word "Poleon"
and the skull and cronsborvea.
(B) OU»tr (orlciCr eefeoorU*. The
statement of practical treatment U not
required on the Iron I panel except a*
described In paragraph IhKIHIIIMA) of
IhU •ecllon. The applicant may. how-
ever. Include *uch a front panel atate-
menl at hU option. Statement* of
practical treatment art, hoarever. re-
quired elsewhere on th« label In
accord with paragraph (hHJ) of ttito
•ectlon If they do not appear on the
front panel.
llv» Placemen < ana* JTOmlsKWCc. All
the require front panel warning vtate-
ments *hall be grouped together on
the label, and shall appear with «utfV
clent prominence relative to other
front panel text and graphic material
to make them unlikely to be over-
looked under customary oondlUone of
purchase and u*e The following table
«how« the minimum trpe stee require
menu for the front panel warning
statement* on various sixee of labekr
40—f>r*re«rUfl ef Efrvwvmwtenl
* vrf.
••*)*..
_ J
It
II
(1) Other rtwvlrrrf verwfnp* an*" pre-
cenfloita.ry ttmtrwtfntt. Th«i warnings
and precautionary statement* a* re-
quired below thall appear together on
the label under the general heading
"Precautionary Statement*" and
under appropriate nibheadlng* of
"Haaard t« Humane and" Domestic Anl-
male,** " Environmental Hazard" and
"Fhyvkml or Chemical Hazard."
(ll J/aMwnf to nameft* **4 tomtttic
m*lm*U. (A) Where • hacard eiUU to
humane or dumeaUc animal*, precau-
Uonary etatetnenU are required Indl
caUnc the particular hazard, the
routed) of eipocure and the precau-
Uone to be taken to avoid accident.
Injury or damajre. The precautionary
paragraph •hall be Immediately pre-
ceded by the appropriate hazard
(B) The fottowlnn table depict* typi-
cal precautionary •tatemenU. Thaw
•ialemenU mivt be modified or ex-
panded to reflect *p«clftc haxard*.
yy •*•! 0« MI sri to «r«* ••
tl
IM.
. Where a
hazard ckUU to rton tarvet onranlame
eicludln* humane and domeeUc ani-
mal*, precautionary etatententa are re-
quired *lalln| the nature of Ui«
and IHe a(>i>rof>rtat« P€«C»U-
to »»old
Injury or damage. Kiamptea of the
haxard *tatemenU and the circum-
stance* under which they are required
follow:
(A) If a peatldde Intended for out-
door uve contain* an actl** ln*re Por U*e«i InvoUIn* lollur Mppllrx
lion to agricultural rrnrM. Inrrnln. or
nh*de tree*, or for mo*qnllo ohnlr
menl trralmenl*. pmllcldrn Inilr In
polllnntlnx Irveclx mu^l hcur npproprl
•Ic litbcl rnullorw
(F) For all outdoor n«r" other limn
unuKtlc appllcatlonii the l«rx-l muni
brnr the caution "Keep out of Inker
pond* or Hlreitrn*. Do not ronlnmliiRlr
»i»(rr br clennlnx of eniilpmrnl or din
poanl of wa.ite«."
(Ill) /Vivifcaf or chrmlral ftarnnli
W»rnln« uliitemenl* nil the Hwrnmnhll
Ity or exploaUe chararl^rlnllm nf Ihe
»re required an follown
•. •<• OP-I tew Do «M pwctw. f fcfc«M.
a~. 0» « pram . krt,.^.
»»*.M.M ««« in- r ~r ..„.
(I) DlrrcHoni /or l/ie—(I) Ofnerat
rrqutremtnti—(I) Xtteouacv and clar-
ity of Atnctlont. Direction* for u*e
must be staled In terms which can be
easily read and understood by the
average person likely to u*« or to *u-
pervlse the use of the peiillclde. When
followed, direction* must be adequate
to protect Ihe public frorq fraud $nd
from personal Injury and to prevent
unreasonable adverse effect* on the
environment.
(II) Placrmmt of direction* /or tut.
Directions may appear on any portion
of the label provided that they are
conspicuous enouith to be easily read
by the user of the pesticide product.
Directions for UAC may appear on
printed or »r«phlc matter which ac-
comp*nln the ixntlclde pro»lrf«* thmt:
(A) If required by the Aienry. nuch
printed or «rnphlc matter Is securely
•llached to each packace of the pext)
clde. or placed within the oulxlde
wrapper or DM:
(R) The label bear* a reference to
the direction* for use In acrtrnipsnyln*;
leaflet* or circular*, sttch as "Ree di-
rection* In the enclosed circular:" and
(C) The Administrator determines
that It I* not necessary for such direr-
lion* to appear on the label.
(Ill) Stceptloni to regalrrmenf /or
rffrecffon for •*«— Detailed direc-
tion* for uae may be omitted from la-
beling of pesticides whlrh arc Intended
for use only by manufacturers ol ttrmt-
uets other than potlclde pnxtiM-ix l>>
thrlr regular manif/actwrlnir
-------
5 142.10
(I) The label clearly §how« thai UMJ
product U intended lor UM only tn
manufacturing, proctsm* and sped fie*
the tvpe The product will not come Into
the hand* ol the general publk eioept
alter Incorporation Into (Intoned prod-
ucU; and
> («) The AdmlnUtrator determine*
that «uch directions are not nrrngairj
to prevent unreasonable adverse ef-
fects on man or the environment.
(B) Detailed direction* (or u*e may
be omitted from the labeling ol pesti-
cide product* (or whkh sale to limited
to physician*, veterinarian*, or drug-
•tot*, provided that:
(/) The label clearly stale* that the
product to (or u*e only by phyiklan*
or veterinarian*;
(2) The Administrator determine*
that such direction* are not neceaaary
to prevent unreasonable adv*r»e el-
(ect* on man or the environment; and
(J) The product to al*o a drug and
regulated under the provtoton* o( the
Federal Food. Drug and Cocmelk Act,
(C) Detailed direction* (or us* may
be omitted from the labeling of pe*U-
clde product* which are Intended (or
uae only by formulalor* In preparing
pealklde* for sale to the public, pro-
vided that:
(II There U Information readily
available to the formulalor* on the
composition, toxklty. method* of us*.
applicable restriction* or limitation*.
and elfectlvervefl* of the product for
pe*lklde purpowe*:
(J) The label clearly itate* that the
product t* Intended for uae only In
manufacturing, formulating, mixing.
or repacking for u*e a* i pe*lklde and
specifies the lypeis) of pealklde prod
•ucU Involved;
(J) The producl as finally manufac-
tured, formulated, mixed, or repack-
aged U registered; and
n a* prescribed In KMtMJ) Immedi-
ately under the heading -Direction*
lor Use."
(M) Immediately below the lUte-
me/il of uae clarification, the slale-
ment "Jt to a violation of Federal law
to u«e thto product In a manner Incon-
ttolenl with It* labeling."
(Ill) The slleXs) of applkallon. aa for
eiample the crop*, animal*, area*, or
ob >ect* to b« treated.
(Iv) The target pesUi> asaodaled
with each alU.
(v> Th* doMge rate associated with
each alte and p«aL
(vl) The method of applkallon. In-
cluding Instruction* (or dilution. If re-
quired, and lype<») of application ap-
paralu* or equipment required.
(vll> The frequency and timing of ap-
plkaUon* ntcmsry to obtain effective
reaull* without caualng unreasonable
adverse effect* on the environment.
(vlll) Spedfk limitation* on reentry
to area* where the poitklde ha* been
applied, meeting the requirement*
concerning reentry provided by 40
CFK Part 110.
(Ix) Spedfk direction* concerning
the storage and disposal of the peatl-
cldn and IU container, meeting the re-
quirement* of 40 CFR Part 145. These
IrwtrucUon* shall be grouped and
appear under the heading "Storage
and DUpoaal." Thto heading must be
•et In type of the same minimum slu*
as required for the child hazard warn-
ing (See Table In | l«l ICHhK I Xl») >
(x) Any HcnlUUonj or rcntrktlons on
u*e requlrec to prevent unreasonable
advera* effects, such a*:
(A) Required Intervals between ap-
plication and harvest of food or feed
crop*.
(B) Rotational crop realrktlons.
(C) Warnings a* required agalrut use
on certain crop*, animals, objects, or
In or adjacent to certain areut.
(D) IReaerved)
(E) For renlrkted u»e ptallcldes. a
statement that the pollclde may b«
applied under the direct supervision of
• certified applicator who la nol phys-
ically present al Ihe slle of application
but nonrlheleaa available to Ihe
person applying, the pesllclde. unless
the Agency has determined thai the
prallclde may only be applied under
Ihe direct supervlnlon of a certified »p
plkalor who U physically presrnl.
(F) Other pertinent Information
which Ihe Admlnlnlralor determine]
to be necenoary for the protection ol
man and Ihe environment.
(j) Slalrment of Vie Clau(/icatto»
Dy October 23. 1919. all peallrlde prod
ucU mu.nl bear on their labels a iilale-
menl of lute clamlflcallon as dencrlbed
In paragraphs (JM 1 > and (3) of thU nee-
lion. Any pontlclde prodiicl for which
some ujien are clamlfled for general line
and othem for renlrlcted line nhall be
separately labeled according In the l«
bclln* nlan<1ardi ael forth In IhM mib-
iiectlon. Hnd iihall be narkelcd an ivrpn
rale products with d fferenl reglnlra-
lion numtxm. one b>-arlng directions
only for general usei.i) aixl the other
bearing dlrecllon* (or r en trie ted IIMS*)
except Ihftt. If a product has both re-
ilrlcled lined) and general uneis). both
of lhe*r unes may appear on a producl
labeled lor rm Irk ted une. Such prod
ucUi nh»ll be subjecl to Ihe provUlons
of | 183 10(jX3>.
(I) OenrraJ Ult ClattUlcalion. Prsll-
clde products bearlnn directions for
iwr<*) elftA.ilfled general iihall be la-
beled with the exact words "General
Climllkatlon" Immediately below the
heading "Direction* for Use." And ref-
erence to the general cliuulf(cation
that suggests or Implies that Ihe gen-
eral ullllly of the pesticide extends
beyond thane purpose* and ujies con-
tained In the Direction* for Us^ will be
considered a false or misleading slale-
menl under the statutory definitions
of mlnhrnndlng.
(3) Iteilricted Uir Cl. and appear
Ing with nufflclenl prominence relative
to other text and graphic material on
5 161.
the fronl panel In make It unllk<
be overlooked under ciwlomary i t
(Ions of purchase and use. Ihe
menl '•Restricted Use Pesticide"
appesr.
Directly below Ihln nUteme
the front panel, a nummary ntnlr
of the terms of restriction linnoi
a precondition to rcjlnlrallon
spprar. If use ls restricted lo cer
applicators. Die following nisi cm.
required: "For retail sale lo am
only by Certified Appllcalmn i>r
sons under their direct siiporvhloi
only for Ihone uaen covered by Uir
titled Applicator's cerllflcallon
however, other rcgulaUuy reslrlcllor
are Imponed. the Administrator wl
define the appropriate wording for
lerms of reslrlcllon by regulation.
(k> Advcrllslng. inciwrvedl
(40 FTt MM*. July I. 1*11: 40 m
AIH i. ins. 40 rn wit. AU« 11. t
amended at 41 TO I7SS. ITb • IS7SI
I Pfl II Criteria for «V(rrmlf.alUnXI) of tftc Act. or
lo hohl a hearing U
no renislrallor
fr dented, as ap
sued, upon a de
Vdmlntatralor Ilial
pr exceeds any o
el forth In para
(Ion. Upon suet
notice of Inte
determine wh
should be cance
proprlale. shall ^
termination by the
the pesticide met
the criteria for B/ak
graph (aX3) of kfils
determination^' the \Admlnlntrato.
shall Issue notice by certified mall to
the sppllca.ryl or reglslrarX as the cax«t
may be. ktnlng that (he Vi>pllcanl or
reentrant/has Ihe oppoWunlly to
submit b*ldence In rehulla\ of niicli
presumpdon In accordance wVli para
graph (4x4) of this section ThV appl).
cant or registrant shall have forty live
(48) /lays frorn the dale such no)irr la
senlr lo submit evidence In rebutlaj nf
lh/ prenumpllon; provided.
for good cause shown the Adm.,
itralor may grant an additional nl«!
-------
PEST/DIS-1
PESTICIDE DISPOSAL INSTRUCTIONS
The laoel of ail products, except those intended solely for domestic
use, must bear explicit instructions about pesticide disposal. The
statements listed below contain the exact wording that must appear on
the laoel :>r these products:
1. -The laoels of all products, except domestic use, must contain the
statement, "Do not contaminate water, food, or feed by storage or disposal.
2. Except those products intended solely for domestic use, the labels
of all products that contain active ingredients that are Acute Hazardous
Wastes or are assigned to Toxicity Category I on the basis of oral or
dermal toxicity, or Toxicity Category I or II on the basis of acute
inhalation toxicity must bear the following pesticide disposal statement:
"Pesticide wastes are acutely hazardous. Improper disposal of
excess pesticide, spray mixture, or rinsate is a violation of Federal
Law. If these wastes cannot be disposed of by use according to
label instructions, contact your State Pesticide or Environmental
Control Agency, or the Hazardous Waste representative at the nearest
EPA Regional Office for guidance."
3. The labels of all products, except those intended for domestic 'use,
containing active or inert ingredients that are Toxic Hazardous Wastes
or meet any of the criteria in 40 CFR 261, Subpart C for a hazardous.
waste must bear the following pesticide disposal statement:
"Pesticide wastes are toxic. Improper disposal of excess pesticide,
spray mixture, or rinsate is a violation of Federal Law. If these
wastes cannot be disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control Agency, or the
Hazardous Waste representative at the nearest EPA Regional Office
for guidance."
4. Labels for all other products, except those intended for domestic
use, must bear the following pesticide disposal statement:
"Wastes resulting from the use of this product may be disposed of on
site or at an approved waste disposal facility."
5. Products intended for domestic use only must bear the following
disposal statement: "Securely wrap original container in several layers
of newspaper and discard in trash."
100
-------
PEST/DIS-2
PESTICIDE ACTIVE INGREDIENTS THAT ARE ACUTE HAZARDOUS WASTES
PESTICIDES ON THE "E" LIST (with RCRA » and CAS »
40 CFR 261 .33(e)
Ac role in
Aldicarb
Aid r i n
Allyl alcohol
Aluminum phosphide
4-Aminopyridine (Avitrol)
Arsenic ac id
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroani1i ne
Cyanides (soluble cyanide salts
not otherwise specified)
Cyanogen chloride
Dieldrin
O,O-Diethyl S-(2-ethylthio) ethyl]
phosphorodith loate (disulfoton)
O,0-Diethyl O-pyrazinyl
phosphorothioate (Zinophos®)
Dimethoa te
0,0-Dimethyl 0-p-nitropheny1
phosphorothioate (methyl parathion)
4,6-Dinitro-o-cresol and salts
4,6-Dinitro-o-cyclohexylphenol
Dinoseb
Endosu1 fan
Endothall
Endrin
Famphur
Fluoroace tarn ide
Heptachlor
Hexachlorohexahydro-exo,exo-
dimethanonaphthalene (Isodrin)
Hydrocyanic acid
Me thorny 1
alpha-Naphthylthiourea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide
(OMPA, schradan)
Parath ion
PhenyImer
Phora te
Potass ium
Propargy1
ric acetate (PMA)
cyan ide
alcohol
Sodium azide
Sodium cyanide
Sodium £ luoroacetat,e
P003
P070
P004
POOS
P006
POOS
P010
P011
P012
P021
P022
P024
P030
P031
P037
P039
P040
107-13-1
116-06-3
309-00-2
107-18-6
1302-45-0
504-24-5
7778-39-4-.
1303-23-2
1327-53-3
592-01-8
75-15-0
106-47-8
506-77-4
60-57-1
298-04-4
297-97-2
P044
P071
P047
P034
P020
P050
P088
P051
P097
P057
P059
P069
P063
P066
P072
P075
P085
P089
P092
P094
P098
P102
P105
P106
P058
60-51-5
298-00-0
534-52-1
131-89-5
88-85-7
115-29-7
129-67-9
72-20-8
52-85-7
640-19-7
76-48-8
465-73-6
74-90-8
16752-77-5
86-88-41
54-11-5
152-16-9
56-38-2
62-38-4
298-02-2
151-50-8
107-19-7
26628-22-8
143-33-9
62-74-8
01
-------
PEST/DIS-3
Strychnine and salts P108
0,0,0,0-Tetraethyl P109
dithiopyrophosphate (sultotepp)
Tetraethyl pyrophosphate . Pill
Thallium sultate P115
ThioEanox P045
Toxaphene P123
Warfarin (>0.3%) P001
Zinc phosphide (>10%) P122
57-24-9
60-41-3
3689-24-5
107-49-3
7446-18-6
39196-18-4
8001-35-2
81-81-2
1314-84-7
50 ACTIVES
II. PESTICIDES DERIVED
[40 CFR 261.31]
FROM TRI-, TETRA-, AND PENTACHLOROPHENOLS
2-Chloroethyl 2-(2,4,6-trichloro-
phenoxy) ethyl ether
Dehydroabietylammon iura
pentachlorophenoxide
Erbon
0-ethyl 0-.( 2,4,5-trichlorophenyl)
ethylphosphonothioate
2,2'-Methylenebis
(3,4,6-trichlorophenol )
(Hexachlorophene)
--Potassium salt ot
--Sodium salt of
--Disodium salt ot
Pentachlorophenol
--Potassium salt of
--Sodium salt of
--Z inc salt of
--Zinc salt of N-alkyl
(C16~C18)~!'3-propaned iamine
--Pentachlorophenyl laurate
Potassium trichlorophenate (2,4,6)
Potassium trichlorophenate (2,4,5)
S i Ivex
--2-Butoxyethy1 ester
--Butoxypolypropoxypropy1 ester
--Butoxypropy1 ester
--C i •>thanolamine salt
--^i isopropanolamine salt
--Dimethylamine salt
--Dipropylene glycol isobutyl
ether ester
--Ethanolamine salt
--2-Ethylhexy1 ester
- - Isoocty1 ester
F027 5324-22-1
F027 35109-57-0
F027 136-25-4
F027 327-98-0
F027 70-30-4
F027 67923-62-0
F027 • 3247-34-5
F027 5736-15-2
F027 87-86-5
F027 7778-73-6
F027 131-52-2
F027 2917-32-0
F027
F027 3772-94-9
F027 2591-21-1
F027 35471-43-3
F027 93-72-1
F027 19398-13-1
F027 53404-07-2
F027 25537-26-2
F027 51170-59-3
F027 53404-09-4
F027 55617-85-1
F027 53535-26-5
F027 7374-47-2
F027 53404-76-5
F027 53404-14-1
102
-------
PEST/DIS-4
--I sopropanolamine salt
--Monohydroxylaluminum salt
--Polypropoxypropy1 ester
— Potassium salt
--Propylene glycol isobutyl
ether ester
— Sodium salt
— Triethanolamine salt
--Triethy lamine salt
--Triisopropanolamine salt
--Tripropylene glycol isobutyl
ether ester
Sodium 2- (2,4,5-trichlorophenoxy)
ethyl sulfate
Tetrachlorophenols
--A1kylamine*amine salt (as in
fatty acids of coconut oil)
--Potassium salt
--Sodlum salt
2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
2,4,5-Trichlorophenol salt of
2,6-bis[(dimethylamino)methyl)
eyelohexanone
2 , 4 , 5-Trichlorophenol, sodium salt
2 , 4 , 6-Trichlorophenol, sodium salt
2,4 , 5-Tnchlorophenoxyacetic acid
--Alkyl C-12 amine salt
--Alkyl C-13 amine salt
--Alkyl C-14 amine salt
--N , N-diethylethanolamine salt
--Dime thylamine salt
--N,N-dimethyllinoLeylamine salt
--N,N-dimethyloleylamine salt
--N-oleyl-l,3-propylene
diamine salt
--Sodium salt
--Triethanolamine salt
--Trlethylamine salt
--Alkyl (C3H7 - C7H9) ester
--Amyl ester
--Butoxyethoxypropyl ester
--2-Butoxyethy1 ester
--Butoxypropy1 ester
--Butyl ester
--Dipropylene glycol isobutyl
ether ester
--2-EthyIhexy1 ester
--1sobu ty 1 esteo
F027 53404-13-0
F027 69622-82-8
F027 83562-66-7
F027 2818-16-8
F027 53466-84-5
F027 37913-89-6
F027 17369-89-0
F027 53404-74-3
F027 53404-75-4
F027 53535-30-1
F027 3570-61-4
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
25167-83-3
53535-27-6
25567-55-9
95-95-4
88-06-2
53404-83-4
136-32-3
3784-03-0
93-79-8
53404-84-5
53404-85-6
53535-37-8
53404-86-7
6369-97-7
53404-88-9
53404-89-0
53404-87-8
13560-99-1
3813-14-7
2008-46-0
120-39-8
1928-58-1
2545-59-7
1928-48-9
93-79-8
53535-31-2
1928-47-8
4938-72-1
103
-------
PEST/DIS-5
— Isopropyl ester F027 93-78-7
--Propylene glycol isobutyl F027 53466-86-7
e ther ester
--Tripropylene glycol isobutyl F027 53535-32-3
e ther es ter
4-(2,4,5-Trichlorophenoxy)butyric F027 93-80-1
acid [2,4,5-TB~]
2-(2 , 4,5-Trichlorophenoxy)ethyl F027 69633-04-1
hydrogen sulfate [2,4,5-TES]
1,4' ,5'-Trichloro-2'-(2,4,5- F027 69462-14-2
trichlorophenoxy)
methanesulfonani1ide [Edolan U]
104
-------
PEST/DIS-6
PESTICIDES THAT ARE TOXIC HAZARDOUS WASTES
PESTICIDES ON THE "F" LIST (with RCRA |, and CAS »
[40 CFR 261 .33( f) ]
Acetone U002 67-64-1
Aery Ion i tri le* U009 107-13-1
Amitrole U011 61-82-5
Benzene* U019 71-43-2
Bis(2-ethyIhexyl)phthalate U028 117-81-7
Cacodylic acid U136 75-60-5
Carbon tetrachloride* U211 56-23-5
Chloral (hydrate) U034 302-17-0
(chloroacetaldehyde)
Chlordane, technical* U036 57-74-9
Chlorobenzene* U037 108-90-7
4-Chloro-m-cresol U039 59-50-7
Chloroform- U044 67-66-3
o-Chlorophenol U048 95-57-8
Creosote U051 8021-39-4
Cresylic acid (cresols)* 1)052 1319-77-3
Cyclohexane U056 110-82-7
Cyc-lohexanone U057 108-94-1
Decachlorooctahydro-1,3,4-metheno- U142 143-50-0
2H-cyclobuta[c,d]-pentalen-2-one
(Kepone, chlordecone)
1,2-Dibromo-3-chloropropane (DBCP) U066 96-12-8
Dibutyl phthalate U069 84-74-2
S-2,3-(Dichloroallyl diisopropyl- U062 2303-16-4
thiocarbamate) (dia 1 late,Avadex)
o-Dichlorobenzene* U070 95-50-1
p-Dichlorobenzene* U072 106-46-7
DichlorodiE luoromethane U075 75-71-8
(Freon 12«)
3,5-Dichloro-N-(1,1-dimethy1-2- U192 23950-58-5
propynyl) benzamide
(pronamide, Kerb*)
Dichloro diphenyl dichloroethane U060 72-54-8
( ODD)
Dichloro diphenyl trichloroethane U061 50-29-3
( DDT)
Dichloroethyl ether U025 1191-17-9
2,4-Dichlorophenoxyacetic, U240 94-75-7
salts and esters (2,4-D)*
1,2-Dichloropropane U083 8003-19-8
1,3-Dichloropropene (Telone) U084 542-75-6
Dimethyl phthalate U102 131- 1-3
Epichlorohydrin U041 106-89-8
( l-chloro-2,3-epoxypropane)
Ethyl acetate U112 141-78-6
Ethyl 4,4'-dichlorobenzilate U038 510-15-6
(chlorobenzi late )
*Proposed tor deletion by TCLP proposal
105
-------
PEST/DIS-7
Ethylene dibromide (EDB)
Ethylene dichloride*
Ethylene oxide
Formaldehyde
Furtural
Hexachlorobenzene*
Hexachlorocyclopentadiene
Hexachloroetnane*
Hydrofluoric acid
Isobutyl alcohol*
Lead acetate
Lindane *
Maleic hydrazide
Mercury
Methoxychlor *
Methyl alcohol (methanol)
Methyl bromide
Methyl chloride
2,2'-Methylenebis
( 3,4,6-trichlorophenol )
(hexachlorophene)
[acute waste per 261.31]
Methylene chloride*
Methyl ethyl ketone*
4-Methyl-2-pentanone
(methyl isobutyl ketone)
Naphthalene
Nitrobenzene*
p-Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentachlorophenol*
(acute waste per 261.31]
Phenol *
Pyr id i ne *
Resorcinol
Safrole
Selenium disulfide
Silvex (acute waste per 261.31]
1,1,2,2-Tetrachloroethane*
Tetrachloroethylene*
2, 3,4,6-Tetrachloroptienol*
[acute waste per 261.31]
Thiram
Toluene *
1 , 1 , 1-Trichioroethane*
(methyl chloroform)
Trichloroethylene*
Tr ichloromonofluoromethane
(Freon 11«)
2 , 4 , 5-Trichlorophenol*
[acute waste per 261.31]
2,4,6-Tnchlorophenol*
[acute waste per 261.31]
U067
U077
U115
U122
U125
U127
U130
U131
U134
U140
U144
U129
U148
U151
U247
U154
U029
U045
U132
106-93-4
107-06-2
75-21-8
50-00-0
98-01-1
1 18-74-1
77-47-4
67-72-1
7664-39-3
78-83-1
301-04-2
58-89-9
123-33-1
7439-97-6
72-43-5
67-56-1
74-83-9
74-87-3
70-30-4
U080
U159
U161
U165
U169
U170
U184
U185
U242
U188
U196
U201
U203
U205
U233
U209
U210
U212
U244
U220
U226
U228
U121
U230
U231
75-09-2
78-93-3
108-10-1
91-20-3.
98-95-3
100-02-7
76-01-7
82-68-8
87-86-5
108-95-2
110-86-1
108-46-3
94-59-7
7488-56-4
93-72-1
79-34-5
127-18-4
137-26-8
108-88-3
71-55-6
79-01-6
75-69-4
95-95-4
88-06-2
106
-------
PEST/DIS-8
2,4,5-Trichlorophenoxyacetic acid U232 93-76-5
(2,4,5-T)*
[acute waste per 261.31]
Wartarin «0.3%) U248 81-81-2
X/lene U239 1330-20-7
Zinc pnospliide <<10%) U249 1314-84-7
83 ACTIVES
107
-------
CONT/DIS-1
CONTAINER DISPOSAL INSTRUCTIONS
The laoel ot each product must bear container disposal
instrjrtions appropriate to the type of container.
1. Ocmestic use products must oear one ot tne following
container •:: :. soosa L statements:
Container Type
Statement
Non-aerosol products
(bottles, c'ans, jars)
Do not reuse container (bottle, can, jar).
Rinse thoroughly before discarding in trash.
Non-aerosol products
bags
I
Do not reuse bag. Discard bag in trash.
Aerosol products
Replace cap and discard containers in
trash. 3o not incinerate or puncture.
2.
based on
All other products must bear container disposal instructions,
container type, listed below:
Container Type
Statement
Metal
conta i ners
( non-aerosol )
Plastic containers
Glass containers
Fiber drums
with liners
Paper and
plastic bags
Compressed gas
cy 1 inders
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
author 1 1 les .
Triple rinse (or equivalent). Then otter
nor recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay out of smoke. 1
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reused^-, dispose of in the same manner.
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Return empty cylinder for reuse (or
similar wording) _
Manufacturer may replace this phrase with one indicating
whether and h'ow tiber drum may be reused.
108
-------
PHYS/CHEM-1
PHYSICAL/CHEMICAL HAZARDS
Criteria R_equired Label Statement
I. Pressurized Containers
F 1 a s n p o i n t at ~>~ below
2 J ° F ; or it there is a
t 1 a s n o a c '< at any valve
opening.
Flashpoint above 20°F
and not over 80°F; or
if the flame extension
is more than 13 inches
long at a distance of
6 inches f rom the
va ive opening.
All Other Pressurized
Containers
II. Non-Pressurized Containers
A. Flashpoint at or below
20°F.
B. Flashpoint above 20°F
and not over 80°F.
C. Flashpoint over 80°F
and not over 150°F.
D. Flashpoint above
150°F.
Extremely flammaole.
Contents under pressure.
Keep away trom tire, spares,
and heated surfaces. Do not"
puncture or incinerate
container. Exposure to
temperatures above L3'J°F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame. Do
not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Contents under pressure.
Do not use or -ore near
heat or open t^ame. Do not
puncture or incinerate
container. Exposure to
temperatures above 13U°F
may cause bursting.
Extremely flammable. Keep
away from fire, sparks, and
heated surfaces.
Flammable. Keep away from
heat and open flame.
Do not use or store near
heat and open flame.
None requ i red•
109
-------
STOR-1
STORAGE INSTRUCTIONS FOR PESTICIDES
Heading:
All products are required to Dear specific laoel instructions
about storace and disposal. Storage and disposal instructions
rrust be jped togetner in the air-ect ions cor use portion ot
the laoel under the heading STORAGE AND DISPOSAL. Products
intended solely tor domestic use need not include the heading
"STORAGE AND DISPOSAL."
Storage Instructions:
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed.
Each registrant must develop his own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, heat, sunlight,
tricticr, or contaminating substances or media.
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
wnile opening or closing container.
4. Instructions-on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been.
spilled, and precautions to minimize exposure if damage occurs.
5. General precautions concerning locked storage, storage-in
original container only, and separation of pesticides
during storage to prevent cross-contamination of other
pesticides, fertilizer, food, and teed.
6. General storage instructions for household products should
enphasize storage in original container and placement in
locked storage areas.
1 10
-------
APPENDIX III
USE INDEX APPENDIX
} \ 1
-------
Compete i urn of Pcceatanle u
OXfiMYu
TQ5LE PC" CONTENDS
Site Name . Dace
TE3=ES~RIALFOCDCRQ2 i
' HQ r i C'_i 1 t ura 1 Crops > i
"ERREE""5 13'- NON-ODD CROP il
( Pgr i cu 1 t ura 1 Crops ) c. I
5REENHOUSE FOOD CROP i7
(Agricultural Crops) c.7
GREENHOUSE NONFOOD DROP 18
(Ornamental Plants and Forest Trees) cS
e £, c!7
ftpole ( rionbear i ng ) 3
Cantaloupe ^
Cat'rots H
Celery 5
Cherry £7
Cher^ry (ncndearing) £,
Citrus Fruits 7, S7
Citrus Fruits (nonbearing) 8
Cotton 8
Cucumber 4
Eggp1 ant 3
Gar 1 ic 10
Ginger 1 1
Honeydew Melons *+
Onion 11
Ornamental Plants £4, c8
Ornamental Plants (interior plantscapes) 30
Peacn d7
Peach (nonbearing) 13
Peanuts 13
Pear 14, 27
Pear (nondearing) 15
Pepper (bell peppers) 15
Peppermint 1&
Pineapp1e 17
Plum £7
Plum (nonbearing) 17
Potato 18
Soybeans 13
Spearmint 16
Squash 4
Strawberry £0, c.1
Sweet Potato £0
Tobacco 23
Tomato 21
Watermelons 4
Issued: £-06-86 III-103801-i 1 12
Provisional Update: 5-11-87
-------
CC'mcena. i urn of ^cceota'Dle Uses
103QO1 OXPMYL
TYPE PEST ICIDE : Nematicide, Insecticide, Pcancide
FQRnULQTIONS:
^ I ' ^ E' •'. )
G i 1 '.'% )
'il /' '_ '2 1 ti / g a i ;
GENE ~^i__ ?~~~, '. '.35 M.Np _lriTMTICNS: Oxamyl ls a RESTRICTED USE PES'l-
<_IDE C'..e to ac^te toxicity ana toxicity to birds ana mammals. «p-
ply ei trier- f.; r-rnu 1 at i on only in cornrnerc i a 1 and farm plantings; do
not use in home plantings. Do not apply in Suffolk and Nassau
Counties, Long Island, NY, except (Reg. No. 3O4-415, 1O% G) for- con-
tainer grown nursery stock, greenhouse, and interior plantscapes.
Do not enter- treated areas for- i^ hours after application unless ap-
propriate protective clothing is worn.
Uhen mixing spray, loading, applying, or otherwise handling, wear
protective clothing, goggles, and an approved mask or respirator.
The use of the 2 pound per gallon formulation in greerihouses is
limited to SLN-FL770G44 and SLN-OH7SOOO1 . The operator must wear- a
suitable full-faced mask and the greenhouse must be ventilated for
1 hour after- treatment.
Oxamyl is tc>xic to wildlife. Cover, collect, or incorporate gran-
ules spilled on soil surfaces.
Do not plan crops other than those with registered oxamyl uses
within 6 months after- the last application.
During aerial application, human flaggers are prohibited unless in
totally enclosed vehicle.
Bee Cantion;
The 2 pound per gallon formulation is highly toxic to bees exposed
to direct treatment or residues on blooming crops or weed's. Do not
apply oxamyl or allow to drift to blooming crops or weeds if bees
are visit i rig the treatment area.
Ground Uiater Qdvisory; Residues of oxamyl can seep or leach
through soil and can contaminate ground water which may be used for
drinking. Users are advised not to apply oxamyl where the water-
table is close to the surface and where soils are very permeable,
i.e., well-drained soils such as loamy sands. Your local Rgricul-
tur-al Soil Conservation Service can provide information on the soil
types in your- area and the location of the ground water.
Dosage rates are given in active ingredient.
agricultural Crop Tolerances (other- than those listed in the text) :
Banana , 0.3 ppm
P'.impk in 2. 0 pprn
Definition of Terms;
SLN - Special Local Needs
Claims for pest control limited to suppression of population are
indicated by an entirely parenthesized pest name.
Issued: £-06-86 I I I- 103801 - 1
Provisional Update: 5-11-87 i i 7
-------
EPP Cc'ivipenc i urn of ncceotaole uses
GXfiriYi_
5 i te and Pest
Dosages ana : o 1 e-ance. ^se,
Forriiu 1 ationis'
i f.i i t a t i c r s
••I-or C-OP
1 H aay pr-enar-vesr ir.ter-vai
tnr-O'.ign c:.O DO'-inas oer acr-e.
DC not graze livesrc'CK i r, t^
or-cnaras.
DC net acDDly at Die cm or- w 11 - i r.
20 days after- bio on:, or fr-r.ur
tniriniriD may occur.
Do not apply were tnan 400 g apply at pink (no petals openea)
when aphids are present i n sigra-
f leant nurnpers. For apple ap^ic.
apoly when 50 percent or- more or
the terminals are infested witn
a 3 - i d s.
I ssued: 2-06-86
I I 1-103801-1
1 14
-------
CornDend i urn of ftcceota^e _,ses
CXPMYL
Site ar,d
Dosages a rig ~o1erance. Use, i_ i M 1t a t i •:•
For mu 1 a t i or, ( s )
, t ; r, uea >
. o '
Soot t eo t erit i -
form 1 ea f 011 ner
( 1arvae)
g gal
ib/gal
/L.)
ueiavec dormant ana foliar- a-^.x-
c a t i c- r-- s . For- first o r o o c i e a ~ -
miner (adults ana larvae), a D D . ,
at p i ri K (no petals o o e r i e c J . f- .;• r •
secona Qrooa ieafnuner (larvae;,
apoiy when there ar-e an average
of 3. or more lar-vae oer leaf in
the sao-feeclirig stage. Ppolica-
t i C'Ti should be maae oefc't-e tne
lar-vae er.ter into the tissue —
f e e a i n g stage.
SLN - Use limited to CT.
Delayed dormant aria foliar- aopli-
catiC'ns. For- first brood leaf-
miner- (adults aria lar-vae), aooiv
at pink (before Bloom). For- se-
cond brood le'afminer (lar-vae),
apply 30 days after- bloom if in-
festation is 2 mines per leaf aria
the majority of lar-vae are sap-
feeders. Repeat i n 2 to ^ wee-s
i f neeaed .
CSi_NJ SLN - Use limited to NY arid Vi.
0.25-0.5 IP/ Delayed dormant arid foliar- appii-
1 (.'0 gal cations. For first orooo leaf-
(c: Ib/gal miner (adults ana larvae), apply
SC/L) orice befor-e bloom. For secona
brc'Od leafminer (larvae), appiy
30 days after bloom if infesta-
tion is 1 mine per- leaf- Repeat
in 3 t c> A meei*s if neeaea.
Whit e apple
1ea fnoooer
ft pp 1 y
o f 1 e a f h o c -
!>. c'5-0. 5 lb/ Foliar- application.
100 gal significant nurnoers
! i lb/c.al pers are present. Repeat at i<.
SC/L) to 1A day iritervals as neeaec.
( n.:>ripear- i n c >
ftpply to trees that will not oe
fruit within 1 c. months after- ^
plicatior. Do not treat oiar,Li
stocK by root dip.
Refer to TERR£5TRIfti_ NONFOOD CROP, (Ornament
-------
aDie _ses
OXP.MVL
Dosaces
Forr,".i 1 at 1 or ( s ^
'ole-'ance, use.
e « - e,
i- '.'a S'
• po'una oer acre for fo
D 1 1 C a t ion.
Preplant soil a DD : i ca t i or,
A. O pounds per acre.
!\ E TJ ~ _
i_ e s i o n
t oae =
Ring n
CS-N-
Roc c-K
toces
J a v a n
St i nc
£ t '.i n t
'- odes
I NJ
riot nefiia
(exceat
ese '
£.0-4.0 Ib/P
(£ 1b/ga i
5C/L)
(1O% G)
0.5-1.0 1 b/ft
i c. 1 b/ ga 1
ner.ia t oces
Ppfiics CSi_"--irL_]
L i r i C' M / r a
fr' l r.er-s
1 ea f-
'.'. 5-1. «.' 1 b/ft
(1 1 b / g a i
SC/L)
Carrot s
I \~r.-^
rrot weev i i
. 5-1.0 i b/
(c 1b/ga1
Precis nt soil application. e
cast; or, for Dana treatment,
proportionately less f orrm.i i at io
Following application arrc ce*:'
planting, i ncc'r pc^ra t e f or MM i a t
'.se
ii: to
incnes into tne soi
Foliar application. Pooiv
weens after planting anc
t o> 5 weens later. Preferaoly, a:
plications snould be usea in CJT,-
juriction with prep 1 ant soil aonli
cation. SLN-IN: If soil aoDiic;
tiori is no't used, apply 10 to It
days after planting ana repeat 1'
to £'1 days later.
Foliar application. Pppiy wrie^
insects first appear ana resea: "i
weekly c>r as needea. Wnere i e a f
ni i r.er- i ri f es t a t i ons C'CCuir anriuai-
iy, apply cl tc> 4 weeks after
olariting and reoeat weekly or a=
neecea. SLN-CA-: P'lay also oe a;
piiea by aircraft.
0. 1 pprn
ftt-plariting soil aop 1 i cat i on
through **.0 pou'nas per acr~e.
Preplant so> i 1 application
B.O pc'unas per acr~e.
SLN-ril: 1A pay prehar-vest
va 1 through 1 . < '.' pouna per'
for foliar application.
Do not apply i n Cft.
5LN — Use limited to Ml.
Foliar application. H vly as
directea spray in a mi , inv.ini c f
gallons per acr^e. Apply '-ID t1-
treatments at c: to 2 wee-< ir.t
vais beginning wnen i ri sects a
pear i n sufficient riijmaer'S to
cause injury.
Issued: £-06-6£
I I 1-103801-4
1 16
-------
•EPS Compete i urn of Accentaole uses
G
bite a r, c H e s'.
DC-sages ana To I eranee, use, — i rn i ^ at i ons
•r :•>-mu 1 a t i or. ( s >
N E •_ & A A A
Root —">'••:" nema —
todes >, except
Javanese )
Spiral nerna-
t o a e s
Sting nernatoaes
St'.mt nematoces
( c. i D / g a i
SC/L >
<10% G)
>i. 'J-A-. i.'' 1 O / fi
i c. i D/ ga 1
SC/L)
( 1 ll'Vi l3 ^
CSLNJ
1.1-1.5 or/
1, GOO ft of
row
L 6 in.
width]
(10* G)
,=> r.t SC' i i a D o i i c a t i on . f--o re-
cast. ftpDiy to tne soil i ri a Min-
imum of cX> gallons per- acre w i T: n -
in 1 weeK of oiantinn. IricoroC'r-
ate to a aeotn of i t •:• t, ir.cnes.
Ht-olanting sc>il aoolication.
I n —furrow. Pooiy in the seea f'.ir-
rc'w during tne planting opera-
tion, ftpoly the soluole concen-
trate f or^mu 1 at i on in a minimum of
c:1!' gallc>ns per- acre.
Sl_N - Use limited to MI.
Pt-planting soil application. fto-
ply C'ver- tne planting area -arid in-
corporate thorouahiy.
Le .
weev i 1
. 0 1 b / «
(1 Ib/ga 1
SC/L)
^.U ppm
1A day preharvest interval
through 1 .'!> pound per acre for
foliar application in F L , MI, o r
PP.
SLN-rL (trimmed celery): 5 oay
preharvest interval through 0.5
pound per- acre or 7 day orehar-
vest interval through 1.0 pouno
per acre for foliar application.
SLN-MI: Preplant soil applica-
tion through 6.0 pounds per- acre.
SLN - Use limited to MI.
Foliar-'application. Apply 3
times at £ to 3 week intervals
when insects appear in signifi-
cant number's to cause injury.
May be applied alone or following
the preplant application.
Issued: £-06-86
I I I-103801-!
1 17
-------
EPfl Compendium of Acceptable Uses
DXftMYL
Site and •-'est
Dosages and Tolerar.ce. Use. Limitations
Form i.i 1 a t ion < s i
t - ~ e s
Pin r. e-
root-knot nemat oaes. apply **.o t
6. C' pounds per acre on a Droac-
cast basis. Incorporate to c.
dept!~i of 4 to £ inches.
SLN - Use limited to M anc --.
Preplant soil application. r^-,:
treatment. ftpply to a band B t:
1£ inches wide on the row. Inc
porate to a depth of <+ inches.
SL.N - Use limited to Ml anc Pfi.
Fo.iar app 1 icat 1 or,. Following
tie pr-eplarit soil application,
aocly 2 times at c1 to 2 w e e K in
tervals beginning c.1 to 2 wee- s
after t t'ansp 1 ant i ng ; or-, if no
pr-eplant a pD 1 i cat i •:• n is niace,
begin as soon as r.ew gr-.;.w*Ti s~C'
a^ter t rarisp i ant i r. :: .
ber-pent i ne
lea f rii i ner
comp i ex
(except
i_ i r i C'my : a
t rofol 1 l J
CSt-N]
0. 5-1.0 1D/P
-
i nf es
tion.
c r a f t .
May pe applied by
I nerry ( n c> n p e a r i r, q )
woDiy to trees that wiii r-'.
^njit within li rnor, thc^ afte'
plication. Do not tre^~ Dl
stoc* by root dip.
Refer- to TESREST^IAL NONFOOD CRQO, ( Ci-r,af.i5' * <
Plants and Forest Trees), Ornamental P^ar.-.E,
tC'f- use arid limitation i r. f C'r-'^a ~ i c r, .
Issuea: i-06-86
I I 1-102601-6
1 18
-------
Compencium of Pcceztas^e -ses
Site ar.c ^esr Dosages ar.c To 1 g--a r re, use,
c or m u i a t i o r i 5 ;.
^T r-'.'. s --•'•:•:=_ -;.'.' pprr
7 a a y ore harvest i r t s"-v a . ~ ~
I.11 pour,- cer- acr-e f : - - - i . ^ a • r
pllcatlO" w i a r.ia » 1 r,i • • • ;
pi icat ions De>-- v ea r- .
SL-N-TX : 7 day crer-ia--v = s: : ' - -r.
va 1 through 11!. 0 pounc. s oe- f : 5
per- season for- foli-ar a iro 1 i Z;--
t i or i.
5i_N-&Z arid CP : 7 ca- rv-=~f . e _
interval thr-ough c..'!' rcv-cr z-:-•
acr-e for" irr-igation wat&- a . i
cation; aric ao not apzi..Y mere
tnan 2.0 pouncs pe-- azr'e i-
5'.i aay periC'C.
D'O not gr-aze livestcz- i r\ t--e^ ;
orcharcs.
Citrus riematooe C5i_Nj Si_N - Use lirnitec tc T X .
ii. 0 - ^. 0 i P / A Collar applicatiC'n. O p p » y 2 T •:
(c ID/gal times between the new flush o~
SC/l_) growth in the spring ar.d trie
fa 1 1 .
(Citrus nema- [5i_Nj 5i_N - Use limited to fiZ ar.c C^.
toae; 0.5-2.0 lp/P Irrigation water application. i
(i IP/gal piy be metering into fiooa irr;
SC/i_) tion water- or into drip ir-r'i^J-
t io n systems. 0 p piy ir the
soring wher, soil temperature i -7
1 19
-------
EPft Cofnoenc i urn or Acceot
aaie uses
Site ar.g Pest
Dosages and Tolerance. Use, _ i .M ; t a t
r or M i.i i a t i on ( s )
0. 0625 — O. 2
iD/lOO Dci
I '.i D t o *nj'
cai/t^J
(c. Ib/gai
5C/i_)
F.; i i a r a 20 1 i ca r i or . w ro ; v ^ =
SO Or, as Sicr, iflCc-r.t 1 r, f e S t
c' * cay preharvest interval
tnr-ougn 1 . 0 pounc per- acr'e f •'"'
foliar application.
L/C' not grace or feea tr-eatec
cotton to livestock.
Boil weevil 0. 1 25-0.1
Cctton flea- ID/ft
n.:.pr->r- (2 lo/aal
plant SC/^_)
Foliar a DP 11 cat ion. npp^y tsne^
damaging populations apoe^- ^('r
repeat as r.eedec to rnainte ' c.
troi. Si_N-TX: may pe acjliec,
a i rcra f t i n a m i n i rin.if.i .:• ^ 2 c
-------
ornpenc i urn of Pccestaoie
ar.g
Dosages
i- orriiu ; a t i c r- <. s i
c . er ance, use,
tat : or s
< cor. r i n•. ec
I p / M - i 1 i a r- appiicaticn. H P p . / ~
a a '•' a c i r, c c •:• p '.• ^ a t i " r, 5 D P c : " t
p v i 1 a . ^ e D e a t at t t •: i c .- .
tervais for- MO t C' *» a D ^ • i c a t
S •_ ,\ — fl Z aria CM: r^a^ DE? aDL^i
air-craft .
See
ant a i O'.ioe c
c: q q
cs
c.. (-•' ODrn
7 day prei ar- vest ir.ter-vai t n r !•
1 . (j po'.ind per a~re w^e-'i '.isirc
soil a po i i ca t i or, witn f c i i ar- a
Ciicatiori; or- 1 cay p--eiarves-;
inter-val tnrouci 1 . C.1 ^oanc pi -•
acre for foliar application <: r,
O. 5-1.0 1P/P Foliar application. Apply C>-
Coloraao pc'tato (£ la/gal
beet le SC/i_)
l_ea f rn i ners
r^ i t es
ground equipment wneri insect1
first appear-. Repeat at 1 t
intervals as neeceo.
Plant-parasitic soil:
nernatoaes ^.0 io/ft
or
f o 1 i a r- :
O.5 Ib/fi
(2 i b/ga 1
SC/L)
Use limited to areas otner- tnar
CA.
Soil ana foliar- appiicatic^ris.
p j. y t C' the soil as a Dana trea
ment i± t c. 5 weens, after- trans-
planting. Repeat 4 weeks late'
Two to A weeks after the soil
treatments, make i foliar acpl
catiC'Tis Dy gr-ounc eq L> i p-nent at
to c: ween inter-va.s.
Issuea: 2-C'6-86
I I 1-103601-
121
-------
C.PO Cornoenc i urn o* Pcceotaoie uses
GXH"1Yl_
iice ar.c J e s t Dosages ana To 1 erar.ce, _se, _ : • • . T j : : •: r •-
For MM i 3 r 1 or. ( 5 ;
O. 1 por.i
5_*< —03: 1 *• day c^e"1 => •' - F-S •
interval, t ~i rc".i c ~ <* . v o : r :
ac'-e ^o -• s ;• i i a^3..ca"i_f.
''.I i o anc stem C5i_NJ 5i_N - Use 1 in:;-r.ee to C-*.
nematoae 1.5 —A. C' IP/M fit—planting ar,c DC -5- e--e •- c= - .ce
MCAM&^H St uPby-root ( c; Ib/'gai soil app i i ca t i or s. £• - r . > 2.''.. t:
;odes 5C/i_) A. C' pounds oer- acr-e at pla'.t ;r,;.
as an in —f'.irrow pare S3f-e, . r, i.
to 5'."1 gallons, or- a 5 an i r, --.i ••-•.;, „
cr-eric^ using 1.5 t o il.'!' p.:-.. r>cs
per- acr-e i r, 100 tc- 15'J cailC'rs.
fippl> 2.0 t o> A.'.'- p-zurics per- ac-'e
i r> c.1 ' to 5'. gal lens (Pane. <: -
oroaccas"/ as post emergence tr-e^7
riients). Mpoly at flag leaf (I :;.
3 leaf) stage anc repeat at ;*. •:
21 aay intervals. Barid widt-
oer- acre given are on a bre^ae-ias:
oasis; for bana ape 1 i ca4; i e-n !.>•: =
pr-oport i on-at e 1 y less,. M:^.:C?-
tioris s no'.i la be f .;• i ,. e v.ec -".- 'i'-e--
neaa irr-igation e^r- rair :" =• . i <~:~-
in 2 days of treatr.-ent (•;i.J,t:; t:
acre incn).
CSuNj 5i_N - Use iimitea t •: CA.
1. O-ii. 0 IP/ Pr-olaritiriQ ar,c pest-olarit s: . 1
surface & aooiications. Apoly a~ plar.r.nc
(cr Ib/gal as an in—furrow spray folle^ec o>
5C/i_) irrigation. Ppoly c.1 to 2 a r: i" ; •:
na 1 times, at 1 A t o c. 1 cay ir;-.£--
vais. Py injection into sprin -.S1'
1 i r.es e>r furrow i r-r-1 gat i :>r., or- 2>
oariped app 1 icat I'l^n (1 to 2 inc'es
wice) o lac eel o>r tne soil S'..r-f;, r. ?
at t f. e base •:• f ': n e P . a " ': = f e
ed witnin A6 ho-.ir-s a*rp-- =?• '.-"
1 22
Issued: i-0£-S£ I I I-iLoSul-10
-------
£pq Compendium of ficceptaple uses
QXSMYi_
iite ana Mes t Dosages arc To. pi-a nee, Lse, - i m i ~ a t \
- c •T:II.. .at i c r, ( 5 )
!•.-=?'- 0. 1 pom
5_"J—'I : 3' cav D--e~ar-ve
interval t ~ r- o u o h s . '-.- D :•'.
a c r = f o'- s c : i a?"lira'i:". ^ ~ ~ .
u n to 7 wee-s a f t e < • ^ . a r t •. r 5
foi iar apoi icat i c n.
&'.!••-r.;.w j. r,g r.ema- C S i_ N j S i_ N - Use iimitec t: ^'. .
t C'de sc' i 1 : Prep i ant so i i ana / :•'• f :•. i a •• ? - :
NtJB&HM i_esion nema- c.. 'J-s. '.'> Ib/fi cations. fippiy as a pr-i^ar ca = t •: -
toces or- band treatment (using pr :oor t : o'-
Poot—knot nema- foliar: ateiy less formulation) aefc^-e
toaes 0.5-1.O Ib/P planting. I nco'-pc^rat e i to ^
S t i r i g r i e rn a t o ci e s ( c: In/cal inches into the s o i i . P< p c . y
£C/_) foliar sprays i tc 4 wee-^s a^ter'
plant ing ana repeat 14 to c. I cays
later- Foiiar sprays shoalc re
used preferably as a foilow-UP to
the soil application. OR. a^ply
c:.0 t C' 4.0 pc'ij^ics per acr-e cirect
ly to the sc> i 1 by c--;o irr-igat:c-
emitters. fipaly 1 wee^ a^re-'
plariting ar.c repeat a*: 1- c?^ :r-
tervals as r.eecec.
r^ieion See Cantaloupe cluste--.
Or, ; •:• n C'. 1 pprn
SLN-ID, MI, OR, TX, ana ^fi: Is
day preharvest interval tnro'.icr,
O. 5 pound per acre for' foliar
application.
Do not ha-vest tops c>f tre
4. C' pounas per- acre as an cas*. -
fi.irrow bar.d spray i r\ i'".1 to S1 c,
Ions.
123
Issued: i-Ofc-86 I I I - 103601 - 1 1
-------
uompend i urn o f ficceotaole uses
Site ar
,- - - - < CC r, t l nuec '
C5_Nj 5_"- - Use lir.ntec t o M I .
1.1-1.3 or' Preplan t s •:• i i application . £•--.,
1,OOO ft •!' f : n a 6 men oati eve-- sla'ti^a
row ar~ea. I nccr-por-ar e c "ICT-C >.•. gi-, . y .
( 1 C'% G )
CSuNl SI_N - use iirnitec t •: I = .
1.5-^.'I> io/ft ftt-o.ariting anc PC s r e-iier- ger,c =
( c. ID/gal soil aop 1 i cat i ors. Pool/ j.1.1 :;
SC/L.) ^. 0 pouncs per ac^'e at piar,rir,-
as an i ri- f Lir*-C'W oar.c GC-~ay i ' J.
t C' 5O gallons, or as an :r>-f jr-r -.,
ar-er.ci usiric 1.5 to c:. 0 pc-^'ici
per acre in 1 OO to i5O cailo^i..
Apply 2,O to 4. 0 pounds per a~-c-
in £1]) to 50 gallons (banr or
Orc'adcast ) as pC'St ernercerice tr-e^1:
ments. ftpply at flag leaf (i t°:
2 leaf stage) and reoeat at 14 t
cl day intervals. &and .w i c *: -•
snoold be 4 t c> 8 inches. Gallc'
per acre given are on a Droacrc??1
Pasis; for Band application use
proport i onat e 1 y less. Hp^.ica-
tions snoi.iid De followec P/ eve-
head irrigation or" rainfall *~.~~
i n 5 days of treatment ((.'.£5 t:
acr-e i nch ) .
Si_N - Use limited to CH.
l.'!>-c:.0 IP/ Pt -pi ant ing arid post -pi ant soil
surface ft applications. Ppply at -plant ir.:;
< i ID/gal as an iri-furr-ow spray foliowez
SC/i_) irrigation. ftpply i to 3 aaci-
tional times, at 14 to 21 ca/
ir.ter-vals, oy ir.jection into
sprinkler iir.es or furrow irri::
ticn,, or py Paridec applicator
(1 to c: incnes wiae> placed •:•'"
tne soil S'.'. rface at rie ^as^-
tne piar.ts fC'ilow£_ witnir. -»e
nours witn spr-ir, K er- i:>r~ f'.>r . "
irrigat ion.
Issued: i-06-86 I I I-1U3601 - 1 c.'
124
-------
Coriioenc i um of wcceataoie Uses
G X MM Y L_
5 i t e ar,g Pest DC'Saqes ar.c ~o i ef-a nee , use. ^imitation?
For-Vi.i i. a t 1 C'r, i s '
,1 " : : r, ,, c : r, t i nuec >
,_O~-iv't- _/'::' t -i r- i 3 s TS^^J S,_ \ - use iirnitec to ID, ^ I , >_ -
t .-i r : - E: ' .1 . D / g a 1 Fc. liar- a D o ^ i c a t i •:"• . ^zic^v «•-. e '
Su/L-1 i ri sects fir-st appear ir
s i gr, i f i can t numbers ar.c r-eos-at
1^» aay intervals i * r.eeaec.
fijpiv in S'.iff ic:ert water t •:
ootain uniform c:>--er-Jce t, cr-,;
P e a c n (nonpearinc;
AoDly t C' trees t ~ at will r,;. r z- f a -
fruit w i t-h i n i i rii,;«r, t -, s a. " t e r' =- _, -
pl icat iC'r.. DC. riot treat r- . a r t i f :.
stocK .by root C:P.
Refer to TERRESTRIA^ NONFOOD CRO^, ( Or nanie--t a .
Plarits arid Forest Trees;, Ornament a i Plants,
for use ana limitation information.
/cl&OlSfiH Pea r. i.i t E O.ii ppm (peanuts, pear, Lit r u i i s '
i.C' oprn (peanut forage, peanut
hay )
Apply 6 weeWs after- er.ier- pence
tnr-ougn 1 . (j pound per acr-e for-
feit ar apoiicatic.ri.
Pit-plaritiriQ soil app 1 i ca t i C"-i
tnrougn 3. C1 pc.urids per- acr-e.
Do not allow granules to cor.ie in
contact with seea.
Do not apply in CP.
i_ar.ce nefiiatodes 0. 5-c.1. 0 Ib/A fit -p 1 ant i nq arid at-oegcing soil
^esion nema- ( 10'/. G) aop 1 i cat ioris. ftppiy i r, a 7 men
toces bar.d or in-fi.irrC'W at oiar.tirir.
Root -K nc't nerna— If r.eedea, repeat at pegging anc
toaes (except irrigate thoroughly to ^a = - gr~a^
Javanese) uies o.ff fc.iiace ar.a ir.tc. t^e
(Tnrios-i SC' i i .
125
Issued: ci-u&-8£ I I I - 1 L'J-GL'1 - 1 3
-------
tP« Comoenc i urn of wcceptacie Uses
i.-e ana Pest
D o s a c e s ana
For-r.i'.i i a~ i o n ( s
'ol era nee, use, uimttati'
( c on t i nuec
( £ i b / g <=>
N E Zi t< C
IM
-R i r, L r s -a T oees
toaes (exceot
Javanese;
Sting nematoaes
T h r- i D S
^ 1b/aa1
^r-eDictrit or at-s:antinc = :
D i i c g a. ions ae--
acre. Apoly first soray 5 we=-£
after emer-gerice anc the secc'.r
soray £ wee^s after eriier-ger-.ee.
Concent r-at i ng the spray or, t~e
row using 5 cone-type norz.es
oositiorieo over- arid to eac^ sice
of tne rC'W is r-ecor.iriiericiec.
l_ (-• J M U I--
cur-ooear,
rii i t e
mcOaniei spider
rn i t e
Pear- r'.ist mite
Twospott ed
so x cer- rnite
14 day prehar-vest interval
through £. O pouncs per acre.
Do not graze livestoc* in treats
orchards.
Do not apply in CP.
Do not apply at bioom or witnin
50 days after- full bloom, or
fruit thinning may occur-.
Varieties otner- than Bar-tier' an
a'Pnjou snoulc be testec fcr- me
possibility of russet ir.^.
1.5-2.0 iD/P Foiiar- application. Ppaly D/
(2 lo/gal grour.a equiornent i r, liiiu to £*•'.•'•.
SC/i_) gallons per acre wnen rnites rir- = '
aopear. Repeat as neeaec. H ci
lute application is recommence..
Issued: i-06-86
126
-------
i urn of ftcceptaple Uses
^ i t e ana >-• e s 7
os ages ,? ••- a Tolerance,
or ',1 '-i - a r : :••- ' 5 ;
Use, _ '. r.i i t a t i : r. 5
0 D D i v t c trees t T a 7 w i
fruit w 1 t n : r. 1,1 rnor, 7-1 =
application. C : ^ : t t •
oiaritir. c s t •: c - o > f . •- t
sea •"
Refer to TERRESTRIfiL NOrMrOCD C ^ _ - .
Piar.ts ana Forest Trees^, Or r.a Me>-t: ,?
for- use ar,c 1 i rn i t a t i on i nf orrra t i :•" .
-e" T a .
?ppe>
IRACCUfi
peacn
aon i a
Peooer weevi1
Vegetable leaf-
m i ner
. 5-1 . 0 i s/i
( £ 1 o / g a i
5C/L)
2. u
7 oay prenarvest ir,te--vai t~---i"jz'
1.0 pound per acre for fc'i;^-- a -• •
pi i cat ion.
Do not apply as a t^arisolar. t
water treatment G'.: r i »• g pei-'ic^ZE c •
slow plarit grow:~i s-.icn as *~^.e-'
ter.iper'atures fall Qeiow A5 F (7.,
C > , or crop injury may '~es 1.11 t .
Do not apply in CA.
Foliar applicatiori. P p o . y in a
minimum of 1 Ou gallC'r.s per acr-e
wneri insects first appear^. Re-
peat at 1 t c> c. weew intervals or-
as needed.
Ring nerna t c^aes tr-ansplarit
Root—^not nerna- water:
tC'aes (except 0.5 iD/fi
Javanese; and
Sting nernatodcs foliar:
Stuooy-root O. 5-l.C' Id/
nernatodes < «i' lo/ga.
Sturit nematoaes SC/i_>
T'-arisplarit water applicatic^ri ar.c
foliar application. Apply in a
minimum of clOO gallc^ris of trans-
plant water per acr-e. Uncer very
high nernatode pC'pu 1 at i ons, fC'll'i'W
transplant water apolication wit n
a foliar- applicatiori 1<+ days
after transplanting arid continue
as descrioec in aoove L; = e oat-
t ern.
Issued: c:-0£-
I I 1-103801-15
127
-------
EPA Compete i urn of Pccentaoie
re and Pes*. Dosages arid Tolerance. Use, L i •• : t ar i c
r or MM 1 a t i on ' 3 '
. (nay)
ea -'f ' : " r 5_N-"1I ana OR: £' 1 car prena-ves:
iriter-vai cnr-O'.ign 5 . 0 - : r.cs DE-'
acr-e.
i_esiC'r, rieriia- C5^'^J Si_N — Use liMitec t •:• IT I ar.c C-.
toces 1.0—2.0 lD/P Soil/foliar aoolication. Purj.y
flint nemat oae < i ia/cai as mint br-eans winter- cor-n-a":c/
(Long i per i.'g £C/l_) and active i- o o t c r- o w t n D e z i ' = ; r.
e i •:• r, c a r '.i s i a n< in: m ij r.i of 1C1 o a i i o n s per
acre. Aooly tne lower' r-are •: '.
coarse texturec ^sancy; £•:•-..= ^r,-
rnuiCK soils for lesion or M i r -
nema r c ces . Opoly tne nic"i = r ra^
or, fine textured (clay) 5:1.5 -.:,•
rn i nr riewa t C'de. CPpplicatiori t:
neavy soils for- lesion ne^at ooe;
have not proven effective.] cair
fall or sorinWler irr-igatior. (0.
to 1 men) is neecec within 7
oays of treatment to move cne
active ingreaient into the rcct
Issued: £-06-66 I I I - 1 O38O 1 - 1 6 128
-------
EPP, Cornoenc i'-I'll of Pcceataole Uses
C' X H M Y i_
: Dosaces anc Volgrar.ce, Use, i- i iv •. t a t i >: ns
FQ r-rnu ..at 1 or. ( s ;
1. u PCM "-.Dineacc.es •
6 . O pc1". i p i nea c 3 : e or a-'
1 0. O ppm ioinea33le f i r a ;: >= '
5O day prenarv@=t i "' *: e >•• •- => . VN •. t ~ a
rna x i Mi.1.rii o * MCJ . ' ' ?•:.,- a c- ci ac ' ^
on the plant cr-'oc: •:••. a .-.'a - i >v."
of li^.O po u rids per- ac-e •: •'• t n e
ratoon crop.
Do not a DD I y i r CP.
e~.vp'.'C5 [S^J soil: Preplant or- pi'Stoiant s.^.
i f O'r.-ii nerna - 1 . C' —6. 0 1 D / P a pp i i cat i on ana f o i i a r a c z I i ca -
toce or- tion. Ppo 1 y ^. <:> t o 6. 0 poun - ^
tie SC1 : i . Plte'-ria-
SC/i_> tively. apply 1.0 t :• 6. C> pc".'r,as
per- acr-e Or-.;.acrast witnin i wee^
after- planting, or- apply 1.0 t ;>
6. C> pea-no s per- acr-e c i rec t i y to
the soil by or IP irrigation in-
jection within 1 k-vee- after- plan 7
ing. Suosecuent.v, a p p . .• i T:
••+. C' pc'urias per- acre c> i : c
equipment as a fo.xar =,-•••- gr-c-w fc^i :"<•• i n-.
planting. For- tne r-atocr cr~c~
apply 1 to 3 wee-s afte-- nar-vett
•of plar-it crop (Si_N- PR ; . Piter-na-
tively, apply 0.5 to <-+.O pour. PS
per- acre directly t o tne sc i 1 by
drip irrigation injectiC'n at !,
^, or 8 weet-< intervals. It is
recofiirnenaec tnat these suSsec, uer :
app i i cat i ons follow tne aacve Dr-g
plant or pC'Stplarit app icaticn.
C'r- a star,aar-c f urr i pant .
.ijvi ( riO'r.oear- ing;
fipplytC'treestnatwil.riitPC:?
pi i c a t ion.
Refer tc TERRESTRlPu NONFOOD CROP, (Ornament±
Plarits arid Fci>-est Trees), Or-riarner"'t a 1 Piar.ts,
for- use aria limitation information.
1 ?Q
Issued: i-06-B6 I I I - 1 03801 - 17 '^/
-------
S i te ar.g Pest
Cornpena i urn of Acceptance Lses
OXAriYL
Dosages a^-d Tolerance. Use,
Forr.iu 1 a t i on ' s )
^ : rn 1t a t i o i
NEF&E-&H
I RAFPJP
1 as
Colorado ootato
beet i e
F lest Peet i es
Golden riernatoae
CS^N-NV]
Les i or* nema-
t cdes
Potato leaf-
nooper-
Ring nernatodes
(except w
of t n e
Roc*ies;
RC'C'C - Kno t
t C'Oes ( e xceot
i. 0-6.0 1b/ft
c <£• 1 b / g a i
SC/L)
( 1 Or. G)
0. 25- 1.0 I b / ft
( 2 1 b / g a 1
SC/L.)
Sting neniatodes
Tarnisnec plar. t
bug
'-'. 1
7 aay or'e^iar-vest interval t n r^; i.,--,
l.O pound per- acre for foliar- oj-
D i i c a t ion.
In — fur'rcw sC'il a^olicatir^r, .
tnrougn <+.<'.> pounds oer acre; or
preplant soil aoplicatior! fir.:..,;-.
8. O pounds per- acre.
Do not apoly ir. CO.
Preplant or at-planting scii
application. For nernatoaes ar.z
eariy season control of insect;,
apply 2.0 to 4.O pounds per ac-e
in tne seed furrow curing the
planting operation; or, apply H.O
to 6.O pounds per acre as a Dana
or broadcast treatment (use
broadcast for c o1d e n n e r n a t oc e)
witnin 1 week of planting. inccr
porate to a depth of ^ to & inch-
es, ftpply .2 pound per gallon
formulation in a minimum of c.0
gallons oer acre.
Foliar* application. For insects,
apply O. 5 to 1.0 pound per acre,
except in tne Midwest and
Nortneast where 0. c.5 to 1.0 Dounc
per acre may be usea for" Co - oraC'i
pot at o beet 1e. Apply wnen
insects first appear ana repeat
at 5 to 7 day intervals or- a =
needed. May be applied by
aircraft in a minimum of **
gallons per acre.
i ssuec
2-06-86
I I I-103801-18
130
-------
r;lte a r,c nest
Cc-iYiDena i urn of PcceataOie uses.
Ox Ar-iYi_
~G' . ef~ 2 r.ce, 'Jset
Dosages ar.o
For'on.i I a c 1 C' r. ( =
L_ i m i t a t i or.
I R (H •_ H M
NEr&HH
N £ J E4 e M
NEG&HMM
, c s ;
Cyst nematodes
i_es i or. nema —
t oces
Rc'C't-knot nema-
todes (except
Javanese)
St ing nema t O'Oes
(Thrips)
Cyst nematodes
L_ a n c e n e m a t O' C e s
Lesion nema-
t oo es
Ring nematodes
Root—knot nerna-
tooes (except
Javariese)
Stunt nematodes
Ib/A
( 1 0V. G )
bar,a :
0.5-1.0 1 b/ft
C3£ in. rc'w
spacing]
or
broadcast:
i. 0-4. 0 1b/«
(2 Ib/gai
SC/L)
( soy pe=»fis,
st f-aw '
not cut for nay, or- ^eec:
treated for-age to l'i ves v :>c « .
DC' nc't allow granules t •:• c:'f; =
GC'Titact witn seec;.
Do not apply in CM.
Preplar.t or- a t -p 1 ant i rig soi-
appiication. &ar.c treatment.
ftpply in a 7 to 14 inch b=?r-
1 ncor pc'r-a t ed or- in— furrow.
Treat merit will control only
rnocerate i n f est at i ons of cyst
nemat oces.
P replant or at-plartir.g
app 1 i ca t i on. Apply in 1 '.' to IO
gallor.s per- acr-e. HS a ^,
in- fur row barid treatment, apply
over- open Or- ill row at t n e
juncture where trie seec: is
covered with so i 1 to assure
mixing of the f ormu . at i on witn
tne soil around the seed. Or-,
a p o 1 y t C' a 7 to 1 < J
the drill areas up
before planting or
i nch bane i
t c- 1 weeK
at plartinc
c: to 4 inc'iei
Or-, apply =• -: r>c *: ris.
5 pea rm i r, t
'.< a
See Pepper-mi rt- cluster
See Cantaloupe cluste
Issueo: £-06-86
I I I-1036ul-13
13
-------
C.PP Cornpenc i urn of ftcceotacle uses
OXPMYL
Site and Pest Dosages a"ci
Tc' 1 eranee. Use, Limitations
Strawperr/
St OC - '
( r\ o r-. 3 e a r1 n c
ft^riy tc> o 1 a r 1 1 s t n a t i~ i ; i net
bear fruit *M 1 1 n i n 11 montns after
application . Certain varieties
of st rawde'-r 1 es ar-e ser, sitive •: .;•
oxamyl exnibiting sever- e
phytOtOHic syr.ipt Ofi-'a . Kr.ow.
sensitive var-ieties t n o t s~i>: .c
riot De treated w i 1 1 oxaoiyi
incl'-iae Bc'unty, Can.;. 5 a (\r'i2£>i),
Cavalier, Dsrrow, D'.irica,
Ea>-iidawn, Ear^ligicw, Ef.iczre,
Hoiiaay, Mar'late, Midway, M;c
l^ac, NY 1^*09, Ogailalla, Recgl.i.w,
Recstar-, Sec'aoia, Stark Rea,
5'jr,r-ise, and Vies tar. Otner
varieties may be sensitive. Tes
'••r> a small scale to aeterriiir.e
sensitivity prior to ia^ce
aool icat iori.
Refer- to TERRESTRIft^ NONFOOD CRO^. (Ornamental
Plar.ts arid Fc''-est Trees), Ornamental Plants,
for- use ana limitation information.
Sweet Potato
t Lj i
ftC'Ot— Priot nema- preolant:
todes (exceot *>. 0-£. 0 lo/ft
Javanese) (c: lo/gal
Soirai nema- SC/D
t oaes (10% G)
or
i n-f urr-C'W :
c. O-4. 0 i o/ft
(i Ib/ga.
'.i. 1
Preolant soil application tnrougn
6.'.' pounds per- acr-e: or,
at-plan ting (in-furrow) soil
application through 4.0 pounds
per acre.
Do not apply as a transplant
water treatment during periocs of
slow plant growtn such as wnen
temperatures fall below 45 F (7-1
C), or crop injury may result.
Do not apply in Cft.
Pr-eplant or- at-planting so;,.
application. Apply as a preplans
broadcast or banp treatment
(using proportionately less
formulation) in a minimum of 10
gallons per acre. Ppply w 11 n i n 1
ween of pi—nting and incorporate
to a aeatn of 4 to 6 incties. Or,
apply in—furrow in a minimum of
1C"J gallons per acre of
transplant water- d r i r, c tne
P i a r> t 1 n g of Slips.
Issued: £-06-86
I I I - 1
1 -
132
-------
CornpenciuM of Acceptance uses
'=__- t e a ng Pest
Dosages and
r I'l-riiu i a C 1 Of, ( S '
.erance, us& . ^. i M i t a t i <
Ic..11 Douncs per- acr-e oer s,e-
f r, r~ foliar- a D D 1 1 C
I fl< p A A (3 l
NED&CA
IGfiE- AD
N'_ H H cr M M
.UHFHi- n
cs C a u N j
Cc> 1 or a co DC'tatC'
beet 1 e C5i_N]
Flea oeet i es
C o^N j
Gr-eeri oeaci
i i a r apoiicacic''. A D p . y : r. a
rn i ri i dium of i(j>j gaiioris. i5_^ -
Ws or as
neeced.]
.NM^A;
; ^ H A A;
'•tJE-t:
i( .
'tcr^r
(Aphids)
( F i eaDeet ies)
(i_ea f m i ners )
ftem f orr.i r.erna-
toaes (except
Javanese'
5 t i rig ne'.ia t oces
St '.i DOy-root
r.eriia t oaes
Stunt r.eMat odes
( wnit ef1 ies)
4 . 0 - £ . 0 1 P / O
C 1 6-<±^4 i r,.
par.c wiatnj
or
6. i.''-a . 0" i D / A
Pr-eplar, t soil application. T.-. o.
oucniy i ncC'rpCT-a t e to a ceorn .;.
^ t C' £ incnes i fiir;iec i a ^ e . > art^r
apo; icac iori.
1 <.'% G )
1-06-86
III- K)38
-------
Compendium of Pcceptaoie
Site ana Pest
Do sages and
'•:•. er-ar;ce, use, t_ i m •. t at i •:••'.s
i c o
I PML-'-"-J>1'
[ f^, M h-< M '_: t-i
J E U P CM i-1
vi E J & L, E- P
! M P A H • j i-1
C'Ot -K not
t odes
i n u e a '
Nj L 5 ^ N j
(!' . 5 — c. . ' J
(ilo/g
nenia- SC/i_)
bi_N - Use iimitec
i D / H Soil application.
1 to trie SC'il by aria irriaat
Ppoly with first irrigatior.
tne field at 7 to 10 davs.
E".i t't-i-' w i no
toaes [S^Nj
i_ea f rii i ner-s
CSi_NJ
Lesion r.erna-
CS^N] SLN - Use limited to HI.
4.0 — 8.0 ip/P Soil application. Poply c i r e c t . \
(c. ip/gai to the soil by drip irrigation.
Ppply within 1 wee-' after plant-
ing and repeat at 14 to 30 aay
intervals as needed.
•j E u b C
RC'C't — K no t
tC'Ces CS-Nj
Sting neniatodes
JEO&CP
Root ->< not
toaes C5i_N]
- CSLN]
O. 75-1.
lo/fi
( c. i d/ c c
w a c e rme i o r.
Si_N - Use limited to CP. '"
Soil application. Pppiy 0.75
pound per acre using an injection
shank immediately adjacent to the
planter furrow. Ppply to mcist
soil ana follow as soon as D<: : -
siPle with either- sp^inK.er or
furrow irrigatiori water-. M^oiy
1..E5 pounps per- acre as
-------
Coriipena i uni of Mcceptapie Uses
0 x M f v ;_
Dosages ar,q " o . e r a r, c e , L' s e , i_ i M 1 1 a t i o r\ s
Form i.i 1 a - : : r, • s -
>- * ea Deet i es
Lesion neriia-
t oaes (except
J a v a n e s e >
Root-unot nema-
todes (except
Javanese;
Prep i a r-it :
il. C-b. 0 1 p / P
( c. 1 D / g a i
SC/L)
( 1 0% G)
or
t r-
gri 5 wee«s afrer-
t r'a risp i ant i r(g t n r'O'.i Cn 1 . ' ' DO'.inc
per acre; aria t rar.^c 1 art i~ate'
a3D i i ca t i on tnrougn L'.5 ^i''.ir.a DS--
acr-e or" nreolar-.t s: i 1 <=OD! i r =? - !•:•'.
tnr'O'.ic1"! 6. '!' DC".; nis ?e'- £»cr'e.
Over" -a 3D 1 i cat i on fiiav ca'.ise s t <.( r"> ~ -
i nc of tobacco.
Oreoiarit soil a 02 1 i ca t i on, t^^-'iS-
olarit water apoiication, anc
foliar application. Tr-arisplarit
water- application may De apoliec
alone or following prep 1 ant soil
application. Foliar applications
can follow t ranso 1 ant water- or
preplant soil applications. Pp-
piy as a prep I a nt row treatmer~
i r-, an 18 t C1 2'4 ir.cn pane! : ' a
NT i n i rni.irn C1 f £0 gallons pe-- acr-e
(12,OC>0 row feet), or- as a bro- acr-e.
Incorporate to a deptn .;• f ** t i £
iriches by rc^ary tiller- for- row
treat merit or by disci rig for prcaa
cast and bedding. Transplant
within d.^ hour's after soil treat
rflent. CSLN-NC: May be t a r, -
mixed with 1.0 pouno active ingre
dierit aiacirion in broadcast SP--^^
t C1 control wireworms. - fts a
tr-arisplant water- application, az-
Piy 1 n a minimurii of i >'.•'.> caiions:
C'f t r-ariso 1 ar>t water per- acr~e
using the low rate fcr S,c,'."''
plants per acre or tne n i gn --ate
for- S,t.'OO plants per- acre. HPJ.
-------
Comoendiurn of AcceotaoLe Uses
OX AMYl_
Site ana Pest
Dc' sages ana
F o r m M 1 a t i o n ( s )
Tr. ler~ar.ce. Use, Limitations
•: sacc :• < cont i nued
a seconc directea spray ir. £1., to
^•O gallons deoending on pia".-
sire *+ to 5 wee^s after- t>-ar,s-
plant ing. The use of 2 nozzles
positioned over aria to eac^ sice
of the row is
a i .Plarits ana Forest Trees)
/ .Z^O
/ '.'
Plants
ias (in-
cluaing aople
aonia ana
green peacn
aphid)
&1ac^ vine
i1
gnats
Japanese beetle
Leafhoppers
Leafminers
flea 1 yDugs
Mites
Royal palm bug
Sea i es
Th rips
wn i t ef-1 i es
O.5-1.O lb/
1OO gal
Cmax clOO
gal/A:
or
1. 0-c:. 0 1
[max 60O
gal/A:
or
0. 375-0. 75
oz/5-14
ga1/1,000
so. ft
(2 Ib/gal
5C/L)
For use only in cornrnerc i a 1
houses arid nur'ser-xes. Do not
apply tne sc>l uole/1 iquia cc'
tr-ate f orrnu 1 at i on t o interior
plantscapes or potted plants in
or around domestic areas such as
homes, shopping mails, or- commer-
cial buildings.
Treat and observe a few olants
prior to large-scale application
to a single variety. Do not ao-
ply foli'ar treat merit t o plants
unaer water- stress or plants not
actively growing.
Foliar application. Apply as
needed to maintain control.
Issued: £-06-86
I II-1O38O1-24
136
-------
Compena i urn cf Pcceot.apie Uses
GXPMY'L.
Dosages ana
F ormu j a t i o n < s
'ol era nee, use, ^
i 1 a r i o
NEBPPP
'.g_^~ _g_- - 1 a ^ t s (cont inuea)
pre p1 ant :
6. O-cO. O 1 b/ft
Or"
soil rn i x :
O. c.-O. 6 or /
C'J. ya
or
p O s t o i a r. t :
6. O-c:0. O 1 b/P
Or
0.£-2. 1 g/ 1O
sc. ft
( i (J7. G >
Burrow i ng nema- preplant:
todes £. 0-8. 8 Ib/P
Lesion nema- C r>i i n £0
toae^ gal/P]
Root-wnot nerna- (S Ib/gal
tC'Ges (eHcear SC/L)
Javanese; or
Stir.g neriiatodes 6.0-2ij.0 Ib/P
Stur.t r.ematoaes (10% G)
or-
SC1 1 i mix:
0. 69 o; / 1 C'
gal
or
0. 17-0. c.2 02 /
CM. yd
(c: 1 b/ga 1
SC/L)
Or-
(j. I-C'. £ 02 /
cu. ya
( 1O* G)
Or-
f o 1 i ar- :
i;>. 5- 1 . o i c/
( <:>':> gal
L.nax 2. 'J
i£ 1 b/ ga :
SC/L)
Sc'il aoolicaticr-i. inpoiv as a
prep 1 a r. t so ; i a DD 1 i c a t i on ar.c
i r'CC't- a or- a t e to a aeotn of *+ t c 6
inches. If apDiiea in a oana.
use Dr-opor-tioriateiy less fc'rTiv.i —
1 at ion. Or-, apply as a s o i 1 r.i i K
wh lie t i.imb 1 i n g in a sell rn i x e'~ -
Tne rate given is eauivaient tc>
£/. O t C' iL'. ij pr. i.irics per acre. Or-,
aoply as a pc s r 3 i a r, t soil acoii-
cation. I rnfiiea i a t e 1 y after- appli-
cation, apoly 1 i ncf~i of C've-'^eac
i r--- i g a t i on t c- t n oro LI g r. 1 y was^
granules off foliage a rid into t ne
soi 1.
fay Pe applied as a pretransolant
soil application, postplant soil
application,, as a drench, or as
root, corrn, or Dulb a i p. Fc'iiar
applicatiC'ri may be usea alone or-
a supplemerit to the a f orernent i on-
ec apoiicatioris or other- nernati-
cide treat riier-its. When trariSPlarit-
ing, set plants into soil within
c.** hC'Ur-s after aoplication. Ap-
ply as a prep 1 ant soil applica-
tion and incorporate to a depth
of ^ to & inches. If appliea in
a band, use proportionately less
formulation. Ppply as a soil MIX
while tumbling in a soil rnixer.
Tne rates given are equivalent to
ti. 0 t G' .10. C1 pounds per acre ae-
pend i r.g upon f orrnu 1 a t l on. For
f •: 1 i ar application, aoply ^ tirnes
as a ailute spr'ay at c: t o 3 wee*-
ir, ter-vals. Ppply first spray at
first f i.i 11 leaf or- wneri plant is
in active growth pnase. Pac a
suitaole spr-eader- sticker-. Ppci/
as a p'i'S t pi arit soil application
followed immediately Oy 1 i r.ch of
overhead irrigation to thoroughly
wasn gr-anuies off foliage and
into the SC' i 1 . Ppply as a iiauic
C r' e^c"^ usinc ^ t C' 8 f i i.i i d C'ur.ces
ssuec
I I I-1038>">l-i5
137
-------
C.2C Lc freer.- : '.ir,-. -; f ficceptat-le Uses
u x fl ""i Y,_
S i r e £•' c 3es- DC sages ar.p Tolerance, Use,
~ : r".i .1 . a t ;on(5;
_•':?' e- - t ^ - . => r t s v c :• r. t i n ..i e c .'
pis-.plar. t of solution pet' & ir.cn oc. t; of i
= c i . : to <* f 1 '.i i G ounces cer- <* i r.cn
t. ''-c.'.1. '.' ID/M DC't. As a o i p, place r-r.crs,
or- cor-rns, or- o i j i b s i fi the solutior,
minutes. Use tne
sa.ft higher- rate ana lorvger- sc^a^ir,a
(!'.)% G) time fc>r- mc'r>e severe nernatoce
or- * infestation.
a '-er.cn :
'0. £'5 i D / 1 C'O
or / £ i r, . pot
'!•. 0. 0 1 15 c r / 4
1 r. . COt
(I . 5 ' ca i
C : p :
•. ^- 1 . >.' 1 b/
O. 275-0. 7
o r / 5 gal
< £ 1 b / o a 1
5C/L)
Issuec: i-0£-8£ I I I -103S01-S£ 138
-------
- e ^c : .i'i o * ficrestar.e uses
, i~se, _ i •.• i r a t i :
- c- ^
AoD.y to tr-ees ar,c st'-^wDe
t!"iit t^it^ir-^
1 £ mo n t h s after- a D r ^ i c a r i •:• r-,.
foiiowiric s t r-aiNDer' r- i es ar-e v. •-•: w
to be sensitive to C'xaMvi ar,c
ni i c ^ t e M n i o i t p n y t C' v C' x i c s y 01 D -
t orns : Bour-ity, Can'i'DcS ('^ Y 1 3££ ' ,
Cavalier, Dafr-C'w, D u ri i o p, Ear'ii-
Ga w>, Ear'ligl'i.vv, Efi-jire, M>;. . i '2 a
r^ic.aric, i^icwav, Mic rrac, N'
i^i.'9, Ogali?.ia, Rea g ; ow , Rec-
s tar. SecMC'ia, Star-H Rec. Sur>-
r-ise, ar.a Viestar.
e*er- to GPEENHQL'SE NONFOOD CRO^>. (Drnaroent a i
1 ar. t s ar,c: F .:•!•£? 5 t Tr-ees > , Or name "it a i Plants,
:•'- M se a •" c i i M i T a t i c r, i r. f or-nia t i or-,.
Iss uec :
I I I - 1O56' i -17
139
-------
^ - - •_<; r i .T e'::. 'i •;* Acceptaole Uses
G * h ^ y •_
iite arr -e ;- Dosa:&= ard' ~o»erance. Use. i_ i rn i t at i ons
~ : •-••'.! i at i :>r (5)
rees )
For use only in commercial green-
houses and nurseries. Do nor:
apply tne soKiole concentrate/
liauid formulation to interior
• IMK;;,II pi ant scapes or pcittea plarrts i n
xi iu(-i(':3CH or ar-ound domestic areas sucn as
/- I'.ilfcLM homes, snooping mails, or comn-er-
/ 32'ii'CKjAA cial buildings.
Treat arid observe a few plants
prior- to large-scale application
t •: a single variety.
ids (in- CSLNJ SLN - Use limited to Fl_.
eluding a^ole 0.5-1.0 lb/ Foliar application to greenhouse
aphid and 100 gal grown plants. For i nsect =>, apply
green peacn 'Crna* £00 as needed to maintain control.
aphicr^ gal/ft]' Greennouse must be completely
&lac*v:re or- cl osed for at least d. hours fol-
weevil '. . '!'-£. '".' 1 p / O iC'Wiro treatment.
lOfrFPfifi ~ LI r. g'.i s CJ'ICI'TS [fiiax 6'!'0
jeet 1e ca i/w]
-s or-
ea^r.i: ^e-s '>. 375-<:>. 75
'taiypugs or/5-l^» gal/
:t es 1, OOO sc. ft
'oval D a I n p u g ( £ 1 b / g a 1
les • SC/L)
i PS
". e " 1. i e s
iss.iec: c-0£-86 I I I - 1C'380 1-£6
140
-------
Comoena i urn of HcceotaQj.e Uses
Be_§_t_ Dosages ano Tolerance, Use. L. i rn i c at i ens
.-•:•-• MU 1 a - i on ' s )
^-S—g " ' . 1 A-O. i 9 ID/ p 1 a n_t S'T' i 1 aoalicatiori ar.c i r,cc>r -
•-'-'t-K",.;. t r-ierna- i , ijCaj sa.ft pc>rate t c> a aectn of *+ to & inc~i-
toaes (except or es. If apo.iea in «s paric, use
_avanese> 5c>il mix: orooor-t i or.at e 1 y less f C'r-fin.t : a r i on .
- - - r-. g neriia t oc es '!'. c.-' >. 2 c z / Or-, aco 1 y as a so i . m i v wn i 1 = t Mm
c '.i. v C D 1 i ri g i r. a soil mixer. T n e rare
or- given is eauivalent to &.O to 9.0
cost P 1 ant : POM rids oer acre. Or-, apply as a
£.O-8.0 lc/ft post Diane soil application. Im-
or mediately after aD3iicatic>n, an-
1 '. i. ^» -'!'. 19 ID/ D 1 y i i r.cn of :- ver-nead i r-r i g a 'c i c>n
1 , OOC J sr . f t to t norou g~i i y wa s.~i gr-ari LI 1 e s off
or foliage arid into the soil.
0. £-'j. u g/ 1O
sc. ft
( 1'!'•/. G)
5_K - use limitea to UM.
'e-,i-? t •: c e ij . 1 S-C'. 5 75 Foliar app i i ca t i on to areenno..ise
=<-^- « oz/5-1** gal/ grown Rieger BegC'r.ias. Masly to
1OO so. ft foliage as a directeq spr-ay. MD
(c ID/gal ply at 2 t c> A ween ir.ter-va^s as
SC/L) nee^ea to maintain. cc>r.t ro i .
Gr eenn C'Lise nn.ist 3e cC'r.io 1 et e : v
fc>r- at least c: ho'.ir-s foi-
t r~eat riient .
141
ssuec: 2-06-86 I I I - 1 038'.'1-13
-------
HCCBDT e»C I'e USSS
^ies an
olerance. Use. ._ i m 1 1 at i •: ns
. 1 , OGO sa . ft
Biacw vine or
wee v i i so i i mix:
& u I- 1- <:• WM i r, c riema- O.i-O.Z oz/
t •: CP? c-. . ya
Pone '.is c r,ese oeetle o-i'St D 1 ar,t :
i_ea f nooDers 6. '.''-8. 0 ID/ A
Lea f m: ners C"-
i_esiC'ri r,ema- 0. l^-ij. 19 lb
t •••c. &s 1 , 'i";"!! sc . f t
fea 1 / D'.l C S Cr-
r : t es i:>. £-'.'. 8 c/ I1.'
ficct-Kr.cr ne'iia- sc. ft
toaes (excert <10v. G)
Soil aoolicatiori to greerinouse
g^C'wri plarjts. Aopiy for i nsec t s
arid nernat C'Qes. Mo^.y as a ^r-e-
plant soil app 1 i cat i on and incor--
pc'r-ate to a aeotn of A to : ncn-
es. If appliea in a bane. :e
~r-C'2Or-t i C'r.a t e 1 y less f emu., . 3 - i on.
Or-, apoiy as a so i 1 m i x wnxie c MM
aling in a soil mixer- Tne rate
given is equivalent to 6. 0 to 9.0
counds per' acre. Or, apoly as a
oostpiant soil application. Im-
mediately after ap3 i i cat ion, ao-
b '. y 1 men of overnead irrigation
t C' t ho'rougn 1 y wasn granules off
foiiaae ana into tne so i i .
R'i>y a i oa i M D
Sea i e s
St ing neroa t C'
Tnr- i 23
K ^ I X ftPP'_ I CAT I GN5
Qpplication
Refer to
CRG_P
( ftqr i CM i t ijr a
Cantaloupe CSLN], Ceier-y :5_'*-,
Citrus Fruits C5i_N], Cot tor,
CS_N], Cucurnoer [b'^Nj, n evcew
Melons
-------
_r, c P e s T
:• . ef- a
143
Issuec: ^-0£-8£
I I I - I 028'.- : -2 1
-------
-,- i (.mi of Hcceotao.e Uses
g of ^egis-.ereo Pesticide Products Dy For HIM i at i on
ec: i a t e
e - *. . y unavaiiaole for review
O00352-'.iO27 i G<.'076'3-0052:4 GO
O < '.> 3 7 7 3 - GO 2 5 3 «
«* s i.i s D e n a e a
. a / q a . ( 2 <* % ) s o i M D i e c o n c e n t r- a t e / 1 i q M i a
c > a.v » i (1 i.>56O 1 ;
000552-O0372
AZ80O051 AZ8lC"J25 ftZ850i:'O8 ftZ850'J;'
Cft730i:>l7 Cft8i:)0<;>62' Cft80OOb3 CPSi.HJ.t"
00001 CT780002 CT73O001 DE810011
FL7£i;iC>l3 ^^770033 Fi_77C'C)i+4 FL78IJ047
FL&lOC)i!i2 Fi_8lO|."*2 H173i!"!'i.">6 Ml8lOOG9
nl 81 00 13 M I 82OGi.' 1 ID63»JOl3 luSOOOOt
M I 77<.>O i 0 M I 62''!'022 M I 64i'.)(!iCi5 -M I 850003
^CSl'JOOS ND73(!)C'22* NJ8A(.ij,.
0025 OK 64 GO 20 Pft78i".nJl
OC'33 PR78O003 PRSC'Cn
T X6**'!".' :'.' V&780G18
vT73l'"''l''5 V782i">i'>i''3
r . / .o-,a v a i . ao I e for- f"ev i ew
Iss'.iec: 2-"t-5i 1 I I - 1 0380 : -22 144
-------
0 x nr-1 r _
l-ist;rc T - Derive I 1-1 5 r- e c i e ^ t < =
i c ~ "lav be I r. c i u c e c i r , a " -- "" i " e =
E <-'*-< i^cce z ~. a - . e
cia:::nor, iISO)
, U - c i e T -, v i G - • I - i :
-'iDv . — i -r.ie t ~ . - ---
y i~ i :<• i ^ : " s . ; 3 i •: = -
,%ar,le
Issuea: £-O£-S£
I I I - : O2S-
. r
-------
APPENDIX IV
BIBLIOGRAPHY APPENDICES
-------
BIBGUIDE-1
GUIDE TO USE OF THIS BIBLIOGRAPHY
1. CONTENT OF BIBLIOGRAPHY. This bibliography contains
citations of all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources for studies in this
bibliography have been the body of data submitted to EPA
and its predecessor agencies in support of past regulatory
decisions. Selections from other sources including the
published literature, in those instances where they have
been considered, will be included.
2. UNITS OF ENTRY. The unit of entry in this bibliography
is called a "study." in the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
"studies" generally have a distinct title (or at least a
single subject), can stand alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study-
3. IDENTIFICATION OF ENTRIES. The entries in this bibliography
are sorted numerically by "Master Record Identifier," or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It is not related to the six- digit "Accession Number"
which has been used to identify volumes of submitted
studies; see paragraph 4(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late in the review may be preceded by a nine- character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number is
also to be used whenever specific reference is needed.
4. FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards o the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
147
-------
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four- digit date is -followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??), the Agency was unable to determine
or estimate the date of the document.
c. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets.
do Trailing Parentheses. For studies submitted to the
Agency in the past, the trailing parentheses' include
(in addition to any self- explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
"received."
(2) Administrative Number. The next element,
immediately following the word "under," is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission,
(3) Submitter. The third element is the submitter,
following the phrase "submitted by." When
authorship is defaulted to the submitter, this
element is omitted.
(4) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA accession number of the volume
in which the original submission of the study
appears. The six- digit accession number follows
the symbol "CDL," standing for "Company Data
Library." This accession number is in turn
followed by an alphabetic suffix which shows the
relative position of the study within the volume.
For example, within accession number 123456, the
first study would be 123456- A; the second, 123456-
B; the 26th, 123456- Z; and the 27th, 123456- AA.
148
-------
OFFICE CF PESTICIDE PROGRAMS
REGIS~?,A~I:N S'ANDARD BIBLIOGRAPHY
.a,ions Considered to be Part of tne Data Base Supporting
Registrations 'Jnder the Cxanyl Standard
r ' - . - .
OCC28T23 E.I. du Pont de Nemours & Company (1974) Metabolism of Cxamyl.
Summary of studies 097651-3 through 097651-F. (Unpublished
. study received Jun 14, 1976 under 352-372; CDL :G9?651-A)
00023732 Harvey, J., jr. (19757) Metabolism of 14C-Cxamyl in the lactating
Goat. (Unpublished study received Jun 14. 1976 under 352-372;
submitted by E.I. du Pont de 'lemours L Co., Wilmington, Del.;
CDL:097651-F)
00030920 E.I. du Pont de Nemours & Company (1977) Residue Data: Soybeans.
(Unpublished study received May 30, 1980 under 352-372; CDL:
099443-F)
00036935 Atkins, E.L.; Greywood, E.A.; Macdonald, R.L. (1975) Toxicity of
Pesticides and Other Agricultural Chemicals to Honey Bees: Labo-
ratory Studies. By University of California, Dept. of Entomolo-
gy. ?: UC, Cooperative Extension. (Leaflet 2287; published
study. )
00037130 Holt, R.F.; Pease, H.L. (1974) Results of Tests on the Amount of
Residue Remaining on Treated Crops: "Oxamyl!. Includes undated
method entitled: Determination of Oxamyl residues using flame
photometric gas chromatography. (Unpublished study received Uun
25, 1975 under 5F1650; submitted by E.I. du Pont de Nemours &
00039511 Harvey, J., Jr.; Gerike, P. (19??) Biodegradation of 14C-Oxamyl
in Peanuts. Interim rept. (Unpublished study received on un-
known date under 3G1349; submitted by E.1. du Pont de Nemours a
Co., Wilmington, Del.; CDL :093610-J)
00039513 Manlove, L. (1973) Oxamyl Livestock Feeding Studies: Milk and Meat.
Unpublished study received on unknown date under 3G1349; sub-
mitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.;
CDL:093610-L)
00040494 Harvey, J., Jr.; Han, J.C. (1977) Decomposition of Oxamyl in Soil
and Water. (Unpublished study .ceived Jul 21, 1977 under
352-372; submitted by E.I. du P nt de Nemours & Co., Wilmington,
Del.; CDL:096301-A)
49
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Oxanyl Standard
MRID CITATION
00040496 Harvey, J., Jr.; Bellina, R.; Morales, R.; et al. (1970) Metabolism"
and Biodegradation of Oxamyl. (Unpublished study received Jul
21, 1977 under 352-372; submitted by E.I. du Pont de Nemours &
Co., Wilmington, Del.; CDL:096301-C)
il
00040592 E.I. du Pont de Nemours & Company, Incorporated (1976) Livestock
Feeding Study. (Unpublished study received Oct 21, 1976 under
6F1696; CDL:095326-A)
00040594 Shirasu, Y.; Moritani, M.; Watanabe, K. (1976) Oxamyl Mutagenicity
Study Using Bacteria. (Unpublished study received Oct 21, 1976
under 6F1696; prepared by Institu4te of Environmental Toxicology
Toxicity Dept., submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, Del.; CDL:095326-C)
00040597 Harvey, J., Jr. (1975) Metabolism of Oxamyl in Tomato Fruit. (Un-
published study received Oct 21, 1976 under 6F1696; submitted by
E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:
095326-F)
00040603 E.I. du Pont de Nemours & Company, Incorporated (1976) Results of
Tests on the Amount of Residue Remaining on Treated Crops. (Un-
published study received Oct 21, 1976 under 6F1696; CDL:-
095326-N)
00040605 Han, J.C.Y.; Harvey, J., Jr. (1975) Characterization of 14C-Harvest
Residues in Potato Tubers. (Unpublished study received Oct 30,
1975 under 6F1695; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, Del.; CDL:095227-B)
00040607 E.I. du Pont de Nemours & Company, Incorporated (1975) Oxarayl Resi-
due Data—Potatoes (Tubers). (Unpublished "study received Oct
30, 1975 under 6F1695; CDL:095227-D)
00048060 E.I. du Pont de Nemours & Company, Incorporated (1975) Results of
Tests on the Amount of Residu^ Remai.'ng on Treated Crops: "Oxa-
myl | . (Unpublished study rec •'".ved C .t 30, 1975 under 6F1696;
CDL:095228-B)
150
-------
ati
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
MR ID
CITATION
E-I- du Pont de Nemours and Company, Incorporated (1976) Data Sup-
porting the Use of Vydate-(R)\ L Oxamyl Insecticide/Nematicide
on Celery. (Unpublished study received Oct 27, 1976 under 352-
372; CDL:226801-A)
00063009 Hoberman, A.M.; Mossburg, P.A.; Wolfe, G.W.; et al. (1980) Teratol-
ogy Study in Rabbits: Oxamyl: Project No. 201-545; HLO-0801-80.
Final rept. (Unpublished study received Nov 21, 1980 under 352-
371; prepared by Hazleton Laboratories America, Inc., submitted
by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:
099754-B)
00063011 Da-shiell, O.L.; Hinckle, L. (1980) Oral LD50 Test in Rats — EPA Pro-
posed- Guidelines: Haskell Laboratory Report No. 775-80. (Unpub-
lished study received Nov 21, 1980 under 352-371; submitted by
E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:099754-D)
00063012 Dulka, J.J.; Julius, A.J. (1978)
Oxamyl in Soil. (Unpublished
352-371; submitted by E.I. du
Del.; CDL:099754-E)
Microbial Degradation
study received Nov 21,
Pont de Nemours & Co.,
of 1—14\C-
1980 under
Wilmington,
30063016 E.I. du Pont de Nemours & Company (1980) Residue Summary: Oxamyl —
Pears. (Unpublished study received Nov 21, 1980 under 352-371;
CDL:099754-L)
D0066902 Tayfun, F.O. (1969) Acute Dust Inhalation Toxicity: Haskell Labora-
tory Report No. 280-69. (Unpublished study received Nov 29,
1972 under 3G1316; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, Del.; CDL:092249-N)
0066903 Tayfun, F.O. (1969) One-hour Inhalation Toxicity: Haskell Labora-
tory Report No. 281-69. (Unpublished study received Nov 29,
1972 under 3G1316; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, Del.; CDL:092249-0)
15
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
MRID CITATION
00066914 Knott, W.B.; Johnston, C.D. (1969) Insecticide 1410: Evaluation of
Acute LC\50- for Bluegill Sunfish. (Unpublished study received
Nov 29, 1972 under 3G1316; prepared by Woodard Research Corp.,
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
Del.; CDL:092249-AA)
00066916 Knott, W.B.; Johnston, C.D. (1969) Insecticide 1410: Evaluation
of Acute LC\50- for Rainbow Trout. (Unpublished study received
Nov 29, 1972 under 3G1316; prepared by Woodard Research Corp.,
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
Del.; CDL:092249-AC)
00067234 E.I. du Pont de Nemours & Company (1980) Data Supporting Special
Local Need Labeling for Use of Vydate-(R)\ L Insecticide/Nemati-
cide on Apples in the State of Illinois. (Unpublished study
received Jul 24, 1980 under IL 80/6; submitted by state of
Illinois for du Pont; CDL:243033-A)
00076813 Adamik, E.R.; Criswell, M.K.; Mahler, S.C.; et al. (1981) Long Ten
Feeding Study in Mice with Oxamyl: Project No. WIL-77033; HLO-
252-81. (Unpublished study received May 29, 1981 under 352-372
prepared by WIL Research Laboratories, Inc., submitted by E.I.
du Pont de Nemours & Co., Wilmington, Del.; CDL:070136-A;
070137; 070138; 070139; 070140; 070141; 070142; 070143)
00081618 Interregional Research Project Number 4 (1981) Summary of Residue
Data: A0xamyl/Eggplant Field Trials!. (Compilation; unpublishe
study received Sep 4, 1981 under 1E2566; CDL:070295-A)
00083522 E.I. du Pont de Nemours & Company (1978) Results of Tests on the
Amount of Residue Remaining on Treated Crops: A0xamyl|. (Unpub
lished study received Jul 30, 1979 under 352-371; CDL:'098845-G)
00083524 Zahnow, E.W. (1978) Oxamyl-chicken and Egg Study. (Unpublished
study received Jul 30, 1978 under 352-371; submitted by E.I. du
Pont de Nemours & Co., Wilmington, Del.; CDL:09°S45-K)
152
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
ions Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
00083525 Harvey, j., Jr-. Han> j.c.Y.; Reiser, R.W. (1978) Metabolism of
oxamyl in plants. Journal of Agricultural and Food Chemistry
26 ( 3 ): 529-536 . ( Also-In-unpubl ished submission received Jul 30,
1979 under 352-371; submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL: 098845-L)
00084889 E.I. du Pont de Nemours & Company (1980) -Residues of Oxamyl on
Tomatoes | . (Compilation; unpublished study received Oct 15,
1981 under 352-372; CDL: 2346106-A)
00094660 Dudeck, S.; Bristol, K.L. (1981) Final Report: Single-dose Oral
Toxicity Study in Mallard Ducks: Project No. 201-543. (Unpub-
lished study received Jan 29, 1982 under 352-372; prepared by
Hazleton Laboratories America, Inc., submitted by E.I. du Pont
de Nemours & Co., Inc., Wilmington, Del.; CDL: 246726-A)
00094664 Muska, C.F.; Brittelli, M.R.;' Hall, C.L. (1981) Chronic Toxicity
of Oxamyl to-Daphnia magna-:: Haskell Laboratory Report No. 580-
81. (Unpublished study received Jan 29, 1982 under 352-372;
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
Del . ; CDL: 246726-E)
00113339 E.I. du Pont de Nemours & Co., Inc. (1977) A Determination of Oxamyl
Residues on Treated Crops | . (Compilation; unpublished study
received Mar 17, 1977 under 352-372; CDL: 096042-A)
10113341 E.I. du Pont de Nemours & Co., Inc. (1976). Results of Tests on the
Amount of Residue Remaining on Treated Crops: ^Oxamyl | . (Com-
pilation; unpublished study received Jan 17, 1977 under 352-
372; CDLC095720-A)
0113343 E.I. du Pont de Nemours & Co., Inc. (1976) Results of Tests on the
Amount of Residue Remaining on Treated Crops: "Oxamyl | . (Com-
pilation; unpublished study received Jan 18, 1977 under 352-372;
CDL:095719-A)
0113357 E.T. du Pont de Nemours & Co., Inc. (1974) "Residues of DPX 1410
in Peanuts and Various Other Crops | . (Compilation; unpublished
study received Aug 1, 1974 under 3G1316; CDL: 094669-B)
0113370 E.I- du Pont de Nemours & Co., Inc. (1974) Residue Data: "Oxamyl | .
(Compilation; unpublished study received Oct 31, 1974 under
3G1316; CDL: 095-009-C)
153
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MRID
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
CITATION
00113373 E.I. du Pont de Nemours & Co., Inc. (1972) Results of Tests on the
Amount of Residue Remaining on Treated Crops: A0xamyl|. (Compi-
lation; unpublished study received Dec 1, 1972 under 3G1316;
CDL:095011-L)
00113376 E.I. du Pont de Nemours & Co., Inc. (1973) Vydate Oxamyl Insecti-
cide/Nematicide: Fish Residue Study- (Compilation; unpublished
study received Aug 1, 1973 under 352-371; CDL:009019-A)
001133,80 E.I. du Pont de Nemours & Co., Inc. (1977) Results of Tests on the
Amount of Residue Remaining on Treated Crops: ^Oxamyl|. (Compi-
lation; unpublished study received Aug 17, 1977 under 352-372;
CDL:096320-C)
00113387 E.I. du Pont' de Nemours & Co., Inc. (1979) Results of Tests on
the Amount of Residue Remaining on Treated Crops: ^Oxamyl|.
(Compilation; unpublished study received Sep 14, 1979 under
352-372; CDL:098958-A)
00113389 E.I. du Pont de Nemours & Co., Inc. (1978) Results of Tests on the
Amount of Residue Remaining on Treated Crops: ^Oxamyl|. (Compi-
lation; unpublished study received Nov 17, 1978 under 9E2148;
CDL:097629-A; 098399)
00113410 E.I. du Pont de Nemours & Co., Inc. (1976) AStudy: Vydate L Residue
on Celery|. (Compilation; unpublished study received Jul 28,
1978 under 352-372; CDL:234575-A)
00113412 Heitmuller, T. (1978) Acute Toxicity of H-11738 to Grass Shrimp
...: Report No. BP-78-4-066. (Unpublished study received Sep
13, 1978 under 352-EX-89; prepared by EG & G, Bionomics, submit-
ted by E.I. du Pont de Nemours & Co., Inc., Wilmington, DE; CDL:
235326-A)
00113414 Hollister, T. (1978) Acute Toxicity of H-11738 to Embryos of East-
ern Oysters ...: Report No. BP-78-4-067. (Unpublished study
received Sep 13, 1978 under 352-EX-89; prepared by EG & G, Bio-
nomics, submitted by E.I. du Pont de Nemours & Co., Inc., Wil-
mington, DE; CDL:235326-C)
154
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
MRID CITATION
00113419 Hawaii (1978) -Study: Vydate Residues on Tomatoes|. (Unpublished
study received Oct 29, 1979 under HI 79/8; CDL:241281-B)
00116609 Roberts, N.; Phillips, C.; Chanter, D.; et al. (1982) The Effects
of Dietary Inclusion of Oxamyl on Reproduction in the Mallard
Duck: Report No. DPT 106WL/81992. (Unpublished study received
Oct 3, 1982 under 352-372; prepared by Huntingdon Research
Centre, Eng., submitted by E.I. du Pont de Nemours & Co., Inc.,
Wilmington, DE; CDL:248464-A)
00116610 Roberts, N.; Phillips, c.; Chanter, D.; et al. (1982) The Effects
of Dietary Inclusion of Oxamyl on Reproduction in the Bobwhite-
Quail: DPT 107 WL/8261. (Unpublished study received Oct 3, 1982
under 352-372; prepared by Huntingdon Research Centre, Eng.,
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
DE; CDL:248465-A)
00126690 Interregional Research Project No. 4 (1983) Results of Tests on
the Amount of Residue Remaining on Treated Crops: -Oxamyl|.
(Compilation; unpublished study received Mar 28, 1983 under
352-372; CDL:071504-A)
10129354 E.I. du Pont de Nemours & Co., Inc. (1983) Du Pont Vydate L Insec-
ticide/Nematicide: Bananas: Residue Data. (Compilation; unpub-
lished study received May 23, 1983 under 3F2833; CDL:071622-A)
10134709 Harvey, J. (1973) Additional Studies on the Metabolism and Biode-
gradation of Oxamyl in Plants. (Unpublished study received
1973 under 3G1316; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, DE; CDL:092126-B)
0138996 Interregional Research Project No. 4 (1983) The Results of Tests on
the Amount of Oxamyl Residues Remaining in or on Peppers, In-
cluding a Description of the Analytical Method Used. (Compila-
tion; unpublished study received Feb 16, 1984 under 352-372;
CDL:072368-A)
1141395 Chrzanowski, R. (1984) Soil Column Absorption Studies with Vydate
Oxamyl Insecticide/Nematicide. Unpublished study prepared by
E.I. du Pont de Nemours & Co., Inc. 11 p.
155
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Oxamyl Standard
MRID CITATION
00142126 E.I.du Pont de Nemours and Co., Inc. (1984) Du Pont Vydate L
Insecticide/Nematicide [Use on Bananas]. Unpublished
compilation. 90 p.
00143312 E.I. du Pont de Nemours & Co., Inc. (19??) Oxamyl/DMCF Residue
Analyses - Cucurbits. Unpublished study. 79 p.
00143315 Dickhaus, S.; Heisler, E. (1980) Irritant Effects of Molinate
on Rabbit Eye: 1-3-258-80. Unpublished study prepared by
Pharmatox. 10 p.
00147614 E. I. Du Pont De Nemours and Company (1980) Residue Data
Supporting the use of Vydate L Insecticide/Nematicide on
Celery. Unpublished study. 10 p.
00149231 Mclntosh, C.; Jenkins, J.: Burgoyne, D.; et al. (1984) A
Two- Year Field Study to Determine the Fate of Oxamyl in
Soil during Flood Irrigation. Unpublished study prepared
by E.I. DuPont de Nemours and Co. Inc. 14 p.
00154748 Rao, P.; Wheeler, W.; Dickson, D. (1983) Sorption, Leaching,
and Degradation of Nematicides (Oxamyl and Phenamiphos) in
Three Southeastern U.S. Soils: 1982 Short-term PIAP
Project: Final Report (Report # 2). Unpublished study
prepared by University of Florida. 12 p.
00163605 E. I.du Pont de Nemours & Co., Inc. (1986?) Du Pont "Vydate" L
Insecticide/Nematicide: [Foliar Dissipation Study].
Unpublished compilation. 99 p.
00163606 Du Pont Canada Inc. (1982) Vydate Oxamyl Insecticide/
Nematicide: Applicator Exposure Study. Unpublished
study. 5 p.
05001991 Stevenson, J.H. (1?""8) The acute toxicity of unformulated
pesticides to -orker honey bees (:Apis melliferaLQ .
Plant Pathology 27 (1): 38-40.,
156
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APPENDIX V
FORMS APPENDICES
-------
OMB Aaarov* No. XOO-O46S
FIFHA SECTION 3• rop«n4a>f «
by m« f IFHA
31CK2JI8)
m tru f
O I. I «* Mtwwt tra in « a»«> !!••• m mtftj avt loflrnif rrquirvntnu. It D>« tnt 9 OM QMKICJU tfouo. OECO
iMf Proyvnrat, I mdo» Ox protocaa rtvit I will u«:
Attach separate page with a list of the data requirements your company
agrees to satisfy.
G 2. I tov« «it>r*4 into *i
r*quirvn«ia. Th«
mrOl tm m man affm rt^arrvra unrter FIFRA MCCWMI 3(C)(Z)(3)(fl te atafv itw Idlowus
prvtocMk •* b* aibmirtBd to EPA fry:
NAME OF OTH€fl REGISTWA^T
Attach list of data requirements
LJ 2. I «ndo«t i twn&mt "C*rofcatjo« tf Atmrl o« • nm twUbt* la
nm product]):
Qi i
•ItfMf
(TW apeoa • net
(VI
HEGlSTRAXT-J
SIGMA FURS
OATC
EPA
I II
158
-------
CERTIFICATION OF ATTEMPT TO ENTER
_ m ... ^ INT° AN AGREEMENT WITH OTHER REGISTRANTS
(To&Mitfy. CWT//V41L fourinmtf FOR DEVELOPMENT OF DATA
1. 1 tm duly •uttxxu.d to "ixmm *. Moving finnU) -no .0, ajb^ct to *, recuire-
m^itiof . Not.c» und»r FIFRA S*rT«o 3irtloo jod tutvnit th« d*ti u requirtd by th*t Notica. if rwceiury. However, my firm would prefer to enter
mto an agreement with on« of more otHer reqirtrjntj to develop jointly, or to tfijre in the colt of developing, the following required
itemi or dat«:
3. My firm n*i oHerrd m writing to enter into «jd< tn »o/»ement. Coo««i of the oHtM we in«cn»d. Thit ofltr wtt irrrvooole *nd mcludid in off«f 10 b«
oound 6y in irbitfltion dfrmon under FIFRA Section 3(c)(2)(8)(iii) A finel igrtemmt or c dJta ntied .n pi.^r}(yi (2) Joove o iccorcUrvie «.t", tne Not,^ : uort.ruand SPA w,n o'ompdy .
e .'..-,, my r.-m -..uii *j'J.n,t <3H» lu J»0'd luirenvon of ti ^ntflfontM ,nc!er PlFaa, $.r-.mn :(c((2;(B> ITh,\ vit
>ice^ no; r'alv to ioolican.i fcx n*w prodoctl.) I give £PA ppm.si.on to o.icio*- tr>,i itatemeni upon r,:qu«i
| ' "to s.
59
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PRODUCT SPECIFIC DATA REPORT
EPA Reg. No.
Date
Guidance Document for
Registration
Guideline No.
§158.120
PRODUCT
CHEMISTRY
61-1
61-2
61-3
62-1
62-2
62-3
63-2
63-3
63-4
63-5
63-6
63-7
63-8
63-9
63-10
63-11
63-12
1
Name of Test
Identity of
ingredients
.statement of
composition
Discussion of
formation of
ingredients
Preliminary
analysis
Certification of
limits
Analytical methods
for enforcement
limits
Color
Physical state
Odor
Melting point
Boiling point
Density, bulk-
density, or
specific gravity
Solubility
Vapor pressure
Dissociation
constant
Octanol/water
partition
coefficient
pH
Test not
required
for my
product
listed
above
(cneck
below)
I am complying with
data requirements bv
Citing MRID
Number or
EPA Accession
Number
Suonit-
ting
Data
(At-
tached)
(For EPA Use OnJ
Accession Numbe:
Assigned
160
-------
CMB Approval No. 2070-0057
Expiration Date 11/30/89
GENERIC DATA EXEMPTION STATEMENT
EPA Product Registration Number:
Registrant's Name and Address:
As an authorize.-! representative 3t the registrant of the oroduct identified
aoove, I cert it/ tnat:
(1) I have read and am familiar with the terms of the Notice from EPA dated
concerning a requirement for submission of "generic" data on tne
active ingredient named under FIFRA Section 3(c)(2)(B)
(2) .My firm requests that EPA not suspend the registration of our product,
despite our lack of intent to submit the generic data in question, on the grounds
that the product contains the active ingredient solely as the result of the
incorporation into the product of another product which contains that active
ingredient, which is registered under FIFRA Section 3, and which is purchased by
us from another producer.
(3) An accurate Confidental Statement of Formula(CSF) for the above-identifled
product is attached to this statement. That tormula statement indicates, by
company name, registration number, and product name, the source of the subject
active ingredient in my firm's product, or
The CSF dated on file with EPA is complete, current and accurate and
contains the information requested on the current CSF Form No. 8570-4. The
registered source(s) of Che above named active ingredient in my product(s) is/are
and their registration number(s) is/are .
My firm will apply for an amendment to the registration prior to changing
the source of the active ingredient in our product.
(4) I understand, and agree on behalf of my firm, that if at any time any
portion of this Statement is no longer true, or if my firm fails to comply with
the undertakings made in this Statement, my firm's product's registration may be
suspended under FIFRA Section 3(c)(2)(B).
(5) I further understand that if my firm is granted a generic data exemption
for the product, my firm relies on the efforts of other persons to provide the
Agency with the required generic data. It the registrant(s) who have committed
to generate and submit the required data tail to take appropriate steps to meet
requirements or are no longer in ccnpliance with this Notice's data requirements,
the Agency will consider that both they and my firm are not in compliance and
will normally initiate proceedings to suspend the registrations of my firm's
product(s) and their product(s), unless my firm commit^ to submit and submits
the required data in the specified tune frame. I undf-tand that, in such cases,
the Agency generally will not grant a time extension tor submitting the data.
Registrant's authorized representative:
(Signature!
Dated:
EPA Form 857U-27
(Typed!
161
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United States
Environmental Protaetion
Agency
O«ic*of
Pacttcidei and Toxic Sutwtanc
Washington DC 20460
June 1987
Pesticides
Guidance for the
Reregistration of
Pesticide Products
Containing Oxamyl
as the Active Ingredient
------- |