United StrtM
Environmental Protection
Agancy
Off ice of
Pwticide* and Toxic Subftanc
Washington DC 20460
                         June 1987
Pttticidtt
Guidance for the
Reregistration of
Pesticide Products
Containing Oxamyl
as the Active Ingredient

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          GUIDANCE  FOR  THE
REREGISTRATION OF PESTICIDE PRODUCTS

             CONTAINING

               OXAMYL

       SHAUGHNESSY  No.  103801
      AS THE ACTIVE  INGREDIENT
         CAS NO.  23135-22-0
        EPA CASE  NUMBER 108
  ENVIRONMENTAL  PROTECTION AGENCY
    OFFICE OF  PESTICIDE PROGRAMS

       WASHINGTON,  D.C.  20460

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                        TABLE OF CONTENTS
 I.     Introduction  	  ....... 	   1

 II.    Chemical(s) Covered  by  this  Standard  . 	   4
        A.  Description of Chemical	   4
        B.  Use  Profile .   ......._.	   5

 III.   Agency Assessment 	  .   ...........   6
        A.  Summary	 . .„	6
        B.  Preliminary Science Findings  	   8
        C.  Tolerance Reassessment  	 .16
        D.  Tolerance Assessment System  Reassessment.  . .  17

 IV.    Regulatory  Position and Rationale.  .........  19
        A.  Summary of Positions and Rationales	19
        B.  Criteria for Registration	25
        C.  Acceptable Ranges and Limits  	  26
        D.  Required Labeling	27

 V.     Products Subject to this Standard   .........  33

 VI.    Requirement for Submission of Generic Data 	  36
        A.  What  are generic data?
        B.  Who must submit generic data?
        C.  What  generic data must be submitted?
        D.  How to comply with DCI requirements
        E.  Procedures for requesting a change in protocol
        F.  Procedures for requesting extensions of time
        G.  Existing stocks provisions upon suspension  or
            cancellation

VII.  Requirement for" Submission of Product-Specific  Data.  41

VIII. Requirement for Submission of Revised Labeling  ...  42

IX.   Instructions for Submission	  43
       A.   Manufacturing use products  (sole active)
       B.   Manufacturing use products  (multiple active)
       C.   End use products
       D.   Intrastate products
       E.   Addresses

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                         APPENDICES


   I.  DATA APPENDICES

       Guide to Tables

       Table A

       Table B

       Table C


   II.  LABELING APPENDICES

        Summary of label  requirements  and table

        40 CFR 162.10  Labeling Requirements

        Physical/Chemical Hazards Labeling Statements

        Storage Instructions

        Pesticide Disposal  Instructions

        Container Disposal  Instructions


   III.  USE INDEX APPENDIX


   IV.  BIBLIOGRAPHY APPENDICES

        Guide to Bibliography

        Bibliography


   V.  FORMS APPENDICES

   EPA  Form 8580-1   FIFRA }3(c)(2)(B) Summary Sheet

   EPA  Form 8580-6   Certification of  Attempt to Enter into an
                     Agreement with Other Registrants for Development
                   of Data

EPA Form 8580-     Product Specific  Data  Report (End-Use  Products)

EPA Form 8580-     Formulator's Exemption Statement

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                         I.   INTRODUCTION


               The Registration Standards  Program


  EPA has established the Registration  Standards program  in  order  to
  provide an orderly mechanism by which pesticide  products containing
  the same active ingredient can be reviewed and standards set  for
  compliance with FIFRA.   The standards are  applicable to reregistration
and  future  applications  for  registration of products containing the
same active ingredient.  Each registrant of a product containing an
active ingredient subject to this Standard who wishes to continue to
sell  or distribute that  product must bring his product and labeling
into  compliance  with FIFRA,  as  instructed by this Standard.
Pesticides  have  been grouped into use clusters and will be reviewed on
the  basis of a ranking scheme  giving higher priority to (1)  pesticides
in clusters used on  food and feed crops; and  (2)  pesticides  produced
in large volumes.

The  Registration Standards program involves a thorough review of the
scientific  data  base  underlying  a  pesticide's registration.   The
purpose of  the Agency's  review is to reassess the potential  hazards
arising from the currently  registered  uses of the pesticide; to
determine the need  for additional data on health and environmental
effects; and to  determine whether  the  pesticide meets the "no
unreasonable adverse effects" criteria of FIFRA.   In its review EPA
identifies:

1.  Studies that are acceptable in fulfilling the data requirements
for  the currently registered uses of the pesticide.

2.  Additional studies necessary to support continued  registration.
The  additional studies may  not have been required when the product was
initially registered  or  may be needed to replace studies that are now
considered  inadequate.

3.   Labeling revisions needed to ensure that the  product*is  not
misbranded  and that  the  labeling  is adequate to protect human  health
and the environment.

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The detailed scientific review,  which is not contained  in this
document, but is available upon  request  ,  focuses on the pesticide
active  ingredient.  The  scientific review primarily discusses the.
Agency's evaluation of  and conclusions from  available data  in  its
files pertaining to the pesticide active ingredient.  However,  durirj
the review of these data the Agency is also looking for potential
hazards that may be associated with the end use products that  contain
the active ingredient.   The Agency will  apply the provisions of fiis
Registration Standard to end use products if necessary  to protect
human health and the environment.

The Agency's reassessment  results in the development  its regulacory
position which is contained in Section IV of this  Standard.  Based on
this regulatory position,  the  Agency may prescribe  a variety of steps
to be taken by registrants to maintain their registrations  in
compliance with FIFRA.   These steps may include:

1.  Submission of data  in  support of product -registration;

2.  Modification of product labels;

3.  Modifications to the manufacturing process of  the  pesticide

    to reduce the levels of impurities or contaminants;

4.  Restriction of the  use of the pesticide to certified

    applicators or other specially trained individuals;

5.  Modification of uses or formulation types; or

6.  Specification of packaging limitations.


Failure to comply with these requirements may result in the issuance
of a Notice of Intent to Cancel or a Notice of Intent to Suspend (in
the case of failure to submit data).
  The scientific reviews are available upon request from the
 Information Services Sev- ion,  Room 236,  CM#2, 1921 Jefferson
 Davis Highway, Arlington,  VA.  22202  (Tel. (703) 557-4453).   Ninety days
 after the issuance of the Standard,  the  reviews may be purchased from
 the National  Technical  Information Service, 5285 Port  Royal Road,
 Springfield,  VA 22161.

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In  addition,  in  cases in  which  hazards  to  human  health  or the
environment are identified, the Agency may initiate a special review
of the pesticide in accordance with 40 CFR Part 154 to examine  in
depth the risks and benefits of use of the pesticide.   If the Agency
determines  that  the   risks  of  the  pesticide's  use  outweigh its
benefits, the Agency may propose additional regulatory  actions, such
as  cancellation  of  uses which  have  been determined to  cause
unreasonable adverse effects on the environment.

EPA has  authority under the  Data Call-In  (DCI) provisions of FIFRA
sec.  3(c)(2)(B) to require that registrants submit data to  answer
questions regarding the chemical,  toxicological, and environmental
characteristics and fate of a pesticide.   This Registration Standard
lists the data EPA believes are necessary to resolve concerns about
this pesticide.  These data are listed in the Tables A, B,  and  C  in
Appendix I.   Failure to comply with the  DCI  requirements enumerated in
this Registration Standard  may result  in issuance by EPA of a Notice
of Intent to Suspend the affected product registrations.


Registrants are reminded that  FIFRA sec.  6 (a)(2) requires ±hem  to
submit   factual information concerning possible unreasonable adverse
effects  of  a pesticide at any time  that they become aware of such
information.  Registrants should notify  the Agency  of  any  information,
including interim or preliminary  results  of  studies,  if those  results
suggest  possible adverse  effects  on man or the environment.  This
requirement continues as  long as the products are registered by the
Agency.

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              II.CHEMICAL COVERED BY  THIS  STANDARD
A. DESCRIPTION OF CHEMICAL

Oxamyl  is the American National Standards Institute (ANSI) approved
common  name  for a carbamate insecticide  produced  solely  in  the United
States by E.I. DuPont de Nemours.

The  chemical  name  for  oxamyl  is  Methyl  N'N'-dimethy1-N-
[(methylcarbamoyl)oxy]-1-thiooxamimidate.  Other common names and
trade names include DPX 1410, Vydate,  and thioxamyl  (International
Standardization Organization, ISO).


Empirical Formula:    C7H13N303S

Molecular Weight:     219.3

CAS Registry No.:     23135-22-0

OPP Shaughnessy No.:  103801


CHEMICAL STRUCTURE
                                        o

                       H'C\   II    .N-0-C-NHCH,
                           N-C-CX

                       H//       X
Oxamyl is a white, crystalline,  solid with  a  melting  point  of  100-102
degrees centigrade. Oxamyl  is soluble  in  water at 28g/100g,  methanol
at 144g/100gr.' acetone at 67g/100g,  ethanol  at 33g/100g,  and toluene  at
Ig/lOOg.

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 B.  USE PROFILE

 Type of Pesticide:     Insecticide, nematocide, acaricide.

 Pests Controlled:      Insects, mites, nematodes.

 Registered Uses:       Oxamyl  is registered on a variety of field
                       crops,  vegetables, and ornamentals.  Some
                       products are registered for greenhouse and
                       potted  ornamentals.

 Annual Usage:          Estimated at 580,000 Ibs active ingredient.

 Predominant Uses:      Apples, potatoes, tomatoes.

 Mode of Activity:      Cholinesterase inhibitor. Systemic in plants.

 Formulations:          42%  formulation intermediate.
                       24%soluble concentrate (SC).  2  Ibs ai.per gal.
                       10%  granular (G).
                       There is no technical oxamyl product registered.

 Basic Registrant:      E.I. DuPont de Nemours & Co. Inc.

 Initial Registration:   1974

 Number of  Registrants:  4

 Restrictions:          The  24  SC  product is classified as a Restricted
                        Use Pesticide.   Oxamyl  is  not  allowed  for
                        outdoor application in Suffolk and Nassau
                        counties, New York, as a result of groundwater
                        contamination.

 End-Use Registrations


 Formulation            Section 3^     Section  24C

 Granular                5                2

 Soluble  Concentrate      1              69

 The  following  states have  24(C) registrations  for oxamyl,  the  number
 per  state  is  included in parentheses():  AZ(3), CA(8),  C0(l),  CT(2),
 DE(1),  FL(6),  HI(4),  ID(1),  IL(1),  IN(1),  MA(1), MD(2),  MI(6),  NC(1),
ND(1),  NJ(1),  NM(1),  NY(4),  OH(2),  OR(4), PA(4) ,  PR(2),  SC(1),  TX(4),
VA(3), VT(2),  WA(3), WV(1).

There are  no intrastate products for  oxamyl and no  multiple  active
ingredient  products.

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                      III. AGENCY ASSESSMENT


  A.   SUMMARY SCIENCE STATEMENT


  The  Agency has reviewed oxamyl data in the areas of acute  toxicity,
  subchronic and chronic toxicity,  oncogenicity,  reproductive effects,
  mutagenicity, plant and animal metabolism,  residues, environmental
  fate and  exposure, and ecological effects.   As  a result of this
  review,  the Agency has  determined that  certain  changes  in  the|
conditions of registration,  including specific label restrictions  and
submission of  missing  data,  are  necessary  to maintain  current
registrations of products and support registration of new products
containing oxamyl.  A summary  of  these data gaps and label revisions
appears  in  Table  1.    Note that  this list contains only  summary
information on data gaps.  More  detailed  information can be  obtained
by referring to Table A in Appendix 1.   Based upon a review  of  the
available data  the Agency  has reached the following  interim
conclusions.   A detailed discussion of the  Agency's science  findings
can be found in section III.B entitled  "Preliminary Science Findings".


1. Oxamyl is highly  toxic via the  oral   and  inhalation  routes  of
exposure.   The  manufacturing use  product  has  classified   as
Toxicity Category I.

2. While the available data  are  insufficient  to  permit  a complete
evaluation of the chronic effects from  oxamyl exposure, no oncogenic
response was  noted in a valid mouse oncogenicity  study.   Based upon
that study, the  NOEL for chronic toxicity is 25 ppm and the  LOEL is  50
ppm.   No structural abnormalities  were  reported  in  a rabbit  teratology
study.  The developmental  NOEL was 4 mg/kg/day (HOT)  and the maternal
NOEL is  1  mg/kg/day.

3.  Oxamyl is  highly toxic to birds,  bees and mammals,  and moderately
toxic  to fish.  Technical oxamyl  is moderately  toxic to  freshwater
invertebrates.   However, the  24SC  formulation  is  highly toxic to some
freshwater ./invertebrates.    Uses  of  oxamyl  may  threaten  endangered
species.

4.  Leaching  studies indicate that unaged (parent compound)  oxamyl may
leach  in  certain  soil  types.   Oxamyl  has been found  in- minute
quantities in a small percentage of drinking water wells  in Suffolk
County,  New York  and  in Massachusetts.  Occupational  illnesses h < e
been  reported in California  following   exposure  to spray  dri.:t.

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 TABLE  1.
            SUMMARY OF DATA GAPS AND REQUIRED  LABELING  FOR  OXAMYL
 Toxicology

 Acute  Dermal  Toxicity
 Primary  Eye Irritation
 Primary  Skin  Irritation
 Dermal Sensitization
 21  Day Subchronic  Dermal Toxicity
 Chronic  Toxicity  (rodent & non-rodent;
                                             Oncogenicity  (rat)
                                             Teratogenicity (rat)
                                             Reproduction
                                             Gene Mutation
                                             Chromosomal Aberration
                                             General  Metabolism
                            '50
Ecological Effects

Avian Dietary LC5g (upland & waterfowl;
Field studies (avian & mammalian)
Estuarine and Marine Fish LCC
Fish Early Life Stage
Honeybee Toxicity of Residues on Foliage

Environmental Fate

Hydrolysis
Photodegradation in Water
Anaerobic Soil Metabolism
Leaching and Adsorption/Desorption
                                         Soil Dissipation
                                         Rotational Crops  (confined)
                                         Glove Permeability
                                         Droplet Size/Drift Evaluation
Product Chemistry

Description of Manufacturing Process
Discussion of Formulation and Impurities
Preliminary Analysis of Product Samples
Certification of Ingredient Limits
Analytical Methods to Verify Certified Limits
Physical and Chemical Characteristics
Residue Chemistry

Storage Stability
Plant Residues

Labeling Revisions
                           Animal Metabolism, Ruminant and Poultry
                           Processing Studies
protective Clothing
~_'oundwater  Advisory Statement
Fish and Wildlife Toxicity Warnings
Reentry Restrictions
Restricted Use Classification  (granular)

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B.  PRELIMINARY SCIENCE  FINDINGS


    1oAcute Toxicity

Oxamyl is extremely  toxic to mammals  and is classified in Toxicity
Category I for the oral and inhalation routes of exposure.   Oxamyl
acts by   inhibition of cholinesterase.   Toxic  signs result  fron
excessive stimulation at  cholinergic junctions in the autonomic and
central  nervous systems,  and include  tremors,  fascicu1 ation,
salivation,  labored respirat _ :>n, diarrhea,  and exophthalmos.  Atropine
has been  shown to be  an  antidote in both rats and monkeys.  Studies on
a technical grade product  indicate that  the acute  oral LDcQ for male
rats is  3.1  mg/kg;  female rats,  2.5  mg/kg.   Acute dermal  toxicity
studies   with a technical grade  formulation  were  considered
supplementary because of incomplete  reporting.  An additional  dermal
toxicity study is required.  The  acute inhalation LCcg for a 1 hour
exposure is  0.17 mg/L for the male rat and 0.12 mg/L for the female.
With a 4 hour exposure the acute LC5Q for male rats is 0.064 mg/L.
Limited data  available  indicate that oxamyl  produces some reversible
eye irritation.   These data  are supplementary and an  additional  study
is required.   Dermal irritation data reviewed indicate  that  oxamyl
caused severe systemic effects (cholinesterase inhibition) and some
dermal irritation. The  study is supplementary and an  additional  study
is required.  The limited data do not indicate dermal sens itization
from oxamyl  but  the  study is supplementary and an additional -study is
required.


    2.Subchronic toxicity

The  available  data  include a a  90  day  rat  oral study   which is
considered invalid and a 13  week dog  oral study which is considered
supplementary.  Additional studies are usually required in both rodent
and non-rodent species. However, subchronic oral toxicity data are
superseded by the requirement  for chronic studies in rats,  dogs, and
mice.  No subchronic dermal 21  day study is available for  oxamyl and a
study  is  required.   No  90 day  subchronic  dermal or  subchronic
inhalation study are available.   These studies are not required for
the  presently  registered  use  patterns.    As  Oxamyl  is  not an
organophosphate,  no  subchronic  neurotoxicity  study is required.

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     3.Chronic Toxicity

 Chronic feeding studies in the rat  and the dog have been reviewed and
 found to be  inadequate.   In the rat study, 30 rats/sex/dose were fed
 diets containing 50, 100,  and 150 ppm oxamyl for 2 years.  At the two
 highest  doses decreases in body weights of both male and female rats
 were observed.  No  significant histopathological  changes  were noted in
 the  treated animals.  The NOEL for chronic toxicity.in rats was 50 ppm
 and  the LOEL  was  100  ppm.    This rat  study  is classified  as
 supplementary because of missing histopathology  data  and insufficient
 clinical chemistry.  While no adverse effects were observed  in the dog
 study,  it too  is   classified as  supplementary due to the  lack of
 histopathology on interim sacrificed  animals,  insufficient numbers of
 animals in the  control  and high dose groups, and because the highest
 dose tested  did  not   approach  the  maximum  tolerated  dose.
    4.  Oncogenicity

In an acceptable study,  mice  orally dosed at 25,  50, and 75 ppm oxamyl
for 2 years displayed decreased body  weights  at  the higher two doses,
but no  other  histopathological  changes. Relative to the controls,  no
increase  in tumor incidence  was  found in the treated groups.  Based
upon the mouse oncogenicity study, the NOEL for chronic toxicity in
mice is 25 ppm; and the LOEL  is  50 ppm.   The  rat study also showed no
increase in tumor  incidence but was found to  be  unacceptable  and must
be repeated.


     5.Developmental and Reproductive  Effects

The available teratology data only  partially satisfy the data
requirements.   In an acceptable  rabbit study,  oxamyl was administered
orally at doses of 1, 2, and  4 mg/kg/day-   No developmental effects
were observed  at  any dose  level  and the only  observed change was
decrease  in body weight of the 2 and  4 mg/kg/day groups.  This study
yielded a developmental NOEL  of 4  mg/kg/day (HOT) , and a maternal  NOEL
of 1 mg/kg/day.  In a second study   female  rats were fed oxamyl  at
dietary concentrations of 50,  100,  150, and 300 ppm from day  6 through
day 15 of the gestation period.   While  no functional or structural
abnormalities were reported,  the study contains only  summary data and
is therefore  classified  as   supplementary.   An  additional  teratology
study with  rats is required.  In a 3  generation rodent reproduction
and fertility  study ^he only observed  effect was   a decrease  in
weights of  in  the  wee nings  at  mid and high  doses.  Study deficiencies
include;  an  insufficient number of  litters, no report of the number of
animals,  and  insufficient reporting of data.   The study is classified
as supplementary and another study is required.

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     6.  Mutagenicity

An acceptable  differential toxicity  assay using B._ subtilis indicates
that oxamyl did not cause DNA damage. No chromosomal aberration assays
have been  submitted, and  an  acceptable study is required.   An  Ames
assay  using S_._ tYphj.mi.rJ.um  and £_._ co]^ showed that oxamyl did  not
cause gene muta"tlon.  Similar results were obtained in a host-mediated
assay  using  §_._  ty_phi.mi.r_ium.   However,    the  Ames  assays  lack
confirmation by  another  independent  study and the toxicity of oxamyl
was not evaluated for dose selection.  For the host-mediated study,
certain crucial  information  concerning  clinical  signs  in the treated
mice and the data on the preliminary dose selection  study are  missing.
An acceptable study is required.


     7.  Metabolism

The  two  available  metabolism  studies   do not  fulfill Agency
requirements. One study used only two male  rats.   The other  study used
rat  liver  homogenate.   Both studies are classified as  supplementary.
Additional studies  are required.


    8. Environmental Fate and Ground Water

The available data are insufficient to  fully  assess the environmental
fate of oxamyl,  including the extent of groundwater -contamination,  and
its  persistence in  the  environment.    Oxamyl has  been  found in
drinking-water wells  in Suffolk County,  New  York,  and in  Massachusetts
at  levels from  1 to 395  ppb.   In 1983, the New York  State Health
Department  limit for oxamyl was 50  ppb.   In  1985, Massachusetts also
considered 50 ppb as  a guideline limit for oxamyl.  In'New  York, less
than  0.1%  of  the samples  tested  during the  5 year period from 1980
thru 1985 exceeded 50 ppb.   Oxamyl  residues  were  detected below 50  ppb
in  2.9%  of  the  total  samples   tested  (15,535)  at  an  average
concentration of  10 ppb  and  a  median  concentration  of 3 ppb.  In
Massachusetts,  of  the 146 samples  tested in 1985, only 1 positive
sample at  1 ppb  was  found.
                               10

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  In the  available hydrolysis study,   data to  support the claimed
 quantitative conversion of oxamyl to  oxime  were  not  provided  and  the
 purity  of  the  test  substance  was  not  specified.  Acceptable data from
 this study must  be  provided or  an additional study is required.   The
 available data for photodegradation in water  are not acceptable.  This
 report  contains two experiments.   In the  first, the test substance  was
 not characterized and the recovery rate was not supported by data.   In
 the second,  the  test  solutions were not sterile, the test substance
 was not  characterized,  the  solutions were  not  buffered,  the
 temperature  was  not reported,  sunlight parameters  were not  described
 and there was  no material balance.  Data to  support the reported  98%
 recovery,  purity and  specific activity of the test substance  must  be
 supplied,  or an acceptable study  is required.  The one study  available
 concerning photodegradation in  soil only partially fulfills data
 requirements because  of test  substance purity and because  degradates
 were not  characterized.  Additional  data are not required, however,
 because most oxamyl soil applications  involve  soil  incorporation.

 Available data adequately describe the metabolism of oxamyl in  aerobic
 soil.   Labeled oxamyl at 4 and 20  ppm degraded with a half-life of  14-
 28  days in silt loam soil incubated at  25  degrees  C and 70% water
 holding capacity.   The  major degradate  was carbon dioxide.   Other
 degradates included the oxime and  N,N-dimethyloxamic acid.  Neither of
 the two studies  evaluating anaerobic  soil metabolism  fulfill Agency
 requirements.   In  the first study the test substance purity  was  not
 given,  the oxamyl  was not aged prior to introduction of anaerobic
 conditions,,  soils  were  not  completely  characterized,  and fncubation
 temperatures  were not  reported.   In  the second  study  the  test
 substance was  uncharacterized, the treated soil was not initially aged
 aerobically, incubation temperatures were not reported, degradates
 were not adequately identified,  and the analytical methodology  was  not
 properly described.   Acceptable data are  required.

 Three  studies relative  to leaching and adsorption/desorption were
 reviewed.   The sum of these  data are sufficient to demonstrate  the
 leaching potential  of unaged  oxamyl.   Unaged oxamyl (parent  compound)
 is very mobile in  sandy  loam and silt loam soil  columns  (Average  TLC
 Rf  values were  1.00  and 0.70,  respectively).   Additional data  are
 required  for, aged oxamyl residues employing a column leaching study
 which  includes adequate identification of residues.

 Two terrestrial field dissipation studies were reviewed. The first
 does not fulfill the data requirement  because the maximum application
 rate wrs  not used, the  field test data were incomplete (including
 confirmation of the application rate), and "he test substance  was  not
 adequately characterized.   In  the  second st iuy the maximum application
 rate was not used,   the purity of  the  test substance was not reported,
 soils were not completely characterized,  and  the patterns of formation
and decline  of degradates were not addressed.  Complete studies  are
required. The  requirement for a long-term soil dissipation study is
deferred until  the  receipt of acceptable  field dissipation data.
                               11

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Data  for  confined accumulation on  rotational crops   could not be
validated  as the application rate was not  confirmed by  immediate
posttreatment  sampling.  In  addition,  the test  material  was
uncharacterized,  soil samples  were  not analyzed at the  time  of harvest
of the rotational crops,  residues  other than oxamyl  and oxime were
not identified, and  other deficiencies were noted. Complete  data are
required.   Data for field accumulation are  deferred until  such time as
acceptable confined rotational  studies have  been  received  and
reviewed.

Data for foliar dissipation,   dermal exposure, and inhalation  exposure
were  submitted  and  have been reviewed.  Additional  information is
needed for conversion of the reported data to surface residue  levels.
Soil dissipation studies are not available and will be required for
those  use  patterns  where workers will  be  exposed   directly to
substantial quantities of soil during their  work such  as in the
harvesting of  potatoes,  carrots,  or celery.

A well-water monitoring study  has  been reviewed and found to  be
valid.  Oxamyl was  detected at 5.0 to 5.4 ppb in July in three newly
drilled  wells (8.8  to  12.2  ft.)  located  within  10 feet  (in the
direction of ground  water flow) of  a potato  field on Long Island, NY,
that  had  been treated  with  oxamyl(purity  unspecified)  at yearly
application rates of 6 and 9  Ib.  ai/acre that spring and  the  previous
year.   Subsequent sampling in  August and December showed no  detectable
(<5 ppb)  oxamyl.   Eight  other  wells on Long Island, 30  to 400  ft. "from
potato fields treated with oxamyl at yearly rates ranging from 3  to 11
Ib  ai/acre that  spring and the previous  year were sampled several
times and  no oxamyl residues were detected.

A freezer storage stability study could not be validated as  the method
of  analysis was not  reported.   The  method should be submitted.


      9. Ecological  Effects


Available data adequately describe  the acute oral toxicity of  oxamyl
to  birds (See Table  2,  below). Technical grade 97.1% oxamyl is highly
toxic  to  birds.   The  acute  oral  toxicity  of a 24%  SC formulated
product also indicates  a high toxicity  to birds although there  is no
guidelines requirement for avian  toxicity data  on  formulated products.
Residues of the SC formulation on crops  used  by birds are likely to be
above the  bobwhite  LC50 and  lowest reproductive  effect  level for
waterfowl.  For the granular formulat; c i, assuming a size of  2 mg per
granule (0.2 mg ai) , one granule is approximately equivalent to the
LD50  of a 67 g  bird or small mammal.    Available studies  on avian
dietary toxicity  for  the technical  have been evaluated  and found  to be
inadequate.    Additional  studies   on  both  upland game  birds and
waterfowl are necessary.
                               12

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 Table  2.  The Acute Oral Toxicity of  Oxamyl to Avian Species

 Species       Percent A.I.      LD50,  mg/kg
Mallard         97.1               3.16
Mallard         24                10.75
Bobwhite        24                39.20


Avian reproduction studies for upland game birds and waterfowl have
been reviewed  and  found  to  be  acceptable.  For the bobwhite,  the NOEL
is 50 ppm  (highest dose  tested).   For the mallard the NOEL is 10 ppm
and the LOEL is 50  ppm  (highest dose tested).

Data from  simulated or actual terrestrial field tests are required for
formulated products of oxamyl because EEC's exceed the avian LD50 and
LC50 and  mammalian LD50 levels  as determined in laboratory tests.
These data are required for foliar applications  of 24% soluble
concentrate products and soil applications of  10% granular products.

Available  data are sufficient to satisfy  guidelines requirements for
acute toxicity tests with the technical  grade  product for   both
coldwater and warmwater  species of freshwater  fish (See Table 3).
These data indicate that  technical oxamyl   is moderately  toxic to
fish.    Additional data on a 24%  formulated product indicate moderate
toxicity  to warmwater fish and  slight  toxicity to coldwater fish.

Table 3.  Acute Toxicity of Oxamyl  to  Freshwater  Fish

Species       Percent A.I.     LC50, ppm

Bluegill            90           5.6
Rainbow Trout       90           4.2
Bluegill            24.8         6.1
Rainbow Trout       24          12.4


Studies utilizing Da^p_hrii.a  inagjna indicate that technical oxamylis
moderately toxic  to freshwater  invertebrates  (LC50  5.7  ppm).  No
additional data for the technical are required. The 24 SC  formulation
is highly  toxic to  freshwater  invertebrates,  and  with  an   LC50 for  D_._
magna of   1.95 ppm,  is more toxic than the  technical.   As current
registered uses of  oxamyl  do not include direct application to  water
and do not .result in  EEC's  greater than the freshwater invertebrate
LC5Q,  freshwater invertebrate testing with formulated products ar*> not
required.

The data evaluating the toxicity  of technical  oxamyl  to  estuarine and
marine fish  have been reviewed and found to be unacceptable.   A 96
hour LC50  study for a fish,  preferably Menidia sp. or  spot,  Leiostomus
xanthurus  must be submitted.
                               13

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While no data  evaluating the effects  of technical oxamyl to marine
invertebrates  were available, acceptable data on the 24% formulated
product have been reviewed and  found to  be  sufficient  to fulfill the
shrimp  and  oyster estuarine and marine  organism requirements.   The
ECSOs for grass shrimp  and  eastern oysters  are 0.7 and 0.1 ppm ai,
respectively.   Available studies on fish  early  life stages  have  been
reviewed and found to be unacceptable.   As the aquatic EEC's  from all
foliar uses  of oxamyl at 2.0  Ibs ai/acre  and higher, from 24% SC  soil
applications without incorporation, and  from  10% granular treatments
on peanuts and ornamentals all exceed  0.01 the LC5Q  for rainbow trout,
fish early life stage testing is required.

Aquatic invertebrate  life  cycle  data   evaluating the effects  of
technical oxamyl on Daphnia magna have  been reviewed and  found to
satisfy the invertebrate life  cycle requirements.  No  effects  were
observed at the highest test  concentration of  1 ppm.

Data from honey bee acute contact LD50  studies are  sufficient to
satisfy this guideline  requirement.  This  information indicates that
oxamyl  is,  moderate to  high in toxicity to honey bees.  For  this
reason,  data  from a honey  bee residual foliage  toxicity test is
required and must be submitted.


     10. Endangered Species

The Agency has evaluated the  risk oxamyl   poses to endangered species,
based on jeopardy opinions prepared by  the Department of  Interior's
Office of Endangered Species  (OES)  regarding oxamyl's use on certain
crops.   This analysis  indicates that the  use  of oxamyl on certain
crops  may jeopardize  certain  endangered species.   The Agency has
developed  endangered species labeling  statements which govern the use
of oxamyl in areas inhabited  by  endangered species.  This labeling has
been required through PR Notices 87-4 and  87-5 issued May 1, 1987.
                               14

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    11. Data Call-in Notices Issued

 The Agency has  issued the following 3(c)(2)(B) Data Call-in Notices:.

 Date  Issued     Data Required              Status
05/31/84
05/27/86
Environmental Fate
Hydrolysis
Photodegradati on-water
Photodegradati on-soi1
Aerobic soil
Anaerobic soil
Mobi1i ty
Field Dissipation-soil
Product Chemistry
Water Solubility
Vapor Pressure
Octanol water partition

Foliar Dissipation
Soil Dissipation
Dermal  Exposure
Inhalation Exposure
  Submitted Existing Data.  An
  Agency review of the data
  indicated certain notable
  deficiencies. Registrant
  submitted additional
  information 03/04/87,  and
  04/01/87 which was reviewed
  for this standard.
coefficient

    Registrant response
    reviewed for this.
    standard.
    12. Reported Pesticide Incidents

A  search  of the files in the Pesticide  Incident  Monitoring  System
(PIMS) reveals four incidents reported to the Agency between 1966 and
1979 when PIMS was active.  All  incidents involved human exposure to
oxamyl alone in agricultural  situations.  The circumstances were
described as container failure,  improper storage, ingestion, and
improper disposal.  A fatality was reported in one incident involving
probable container failure (accident undescribed).   The other three
incidents resulted in hospitalizations.
                        v
California, data for the period 1981 through 1985 list the following
occupational  illness for oxamyl;  systemic (13), eye (3), skin (1).
Most exposures apparently involved spray drift.  Four   incidents
occurred during ground application and two during mixer-loader
operations.
                               15

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 C.TOLERANCE REASSESSMENT


 Tolerances have been established for oxamyl in or  on a number of raw
 agricultural commodities at levels between 0.1 and 10.0 ppm.  A
 listing of the established tolerances is located at the end of this
 section. There are no Mexican tolerances  for  the  sites registered for
 use  in  the United States.

 After evaluation of the available residue and  toxicology  studies
 supporting these tolerances,  the following conclusions have been
 reached:


 Residue Data

 1.   Data gaps  exist for  storage  stability.  Upon  receipt  of the
 required storage stability data,  conclusions regarding the adequacy of
 established tolerances may  change.   No tolerances  are presently
 established for residues in or  on  animal commodities.   An evaluation
 of required data for animal metabolism  and residues in feed items may
 indicate  the necessity for  studies  and tolerances pertaining to
 residues in animal commodities.

 2.  Sufficient  data are available to ascertain  the adequacy of the
 established tolerances (40CFR 180.303) for  residues of oxamyl in  or on
 sweet potato,' soybeans,  soybean  straw, eggplants,  peppers, tomatoes,
 cucumber,  honeydew melon,  watermelon,  summer  Bnd winter squash,
 cantaloupes,  apples, pears, peppermint and  spearmint hay,  peanuts,
 peanut hulls, pineapples, and pineapple bran.

 3.  Insufficient data are available to ascertain the adequacy of  the
 established tolerances (40CFR 180.303 and 21  CFR 561.285) for residues
 of oxamyl in or on carrots, ginger, potatoes,  garlic, onions, celery,
bananas,  cottonseed, peanut forage  and hay, pineapple forage, and
 citrus.

 4.  Processing studies are required for  the following commodities:
citrus,  potatoes,  soybeans, tomatoes, cottonseed,  pineapple,  and
peanuts.

 5.  Upon receipt of  the  required residue data,  the commodity  entry
"Root crop vegetables" will be deleted and appropriate  individual crop
 (carrots,  ginger,  potatoes, sweet potatoes, garlic,  onions) or  crop
group (Root and Tuber Vegetables Group and Bulb Vegetables  Group)
tolerances will be established.

 6.  Data are  required to  determine  whether tolerances are needed  to
 support registered uses of oxamyl on nonbearing cherries, peaches,
plums, and strawberries.
                               16

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 7.   As there are  no registered  uses of  oxamyl  on pumpkins,  a
 registrant must  propose a use or the tolerance will be revoked.  This
 use  must  be  identical to  the registered use  on winter squash  (winter
 squash data are used to  support the 2  ppm- pumpkin  tolerance).
 Otherwise the  proposed  use  on pumpkins  must be  accompanied  by
 appropriate residue  data to assess the adequacy of the established
 tolerances.

 8.  Data are  required  to determine the  exposure of man to residues of
 oxamyl resulting from its  use on tobacco.

 Toxicology Data and Acceptable Daily Intake

 An  ADI had  been determined by the  Agency  Reference Dose (RFD)
 committee based upon a 2 year  rat  feeding study.  Compound related
"effects were decreases in body  weights  in  both mid and high dose rats
 of  both  sexes.   The NOEL  in  this study was  50 ppm  (2.5  mg/kg) .
 Utilizing an uncertainty  factor of  100,  the  ADI was set  at 0.025
 mg/kg/day.

 Based  upon  a reevaluation  of the data base, the 2-year rat feeding
 study  is  now classified supplementary.   Nevertheless,  because the sum
 of the available data indicate no increase  in tumors, and there are no
 information to suggest that the ADI  is inadequate to protect human
 health, a provisional  ADI (PADI)  will continue to be based upon this
 study  with the same uncertainty factor until acceptable  studies have
 been submitted and all data gaps have been  filled.

Tolerance Assessment System  Tolerance Reassessment

 1.  The provisional   acceptable daily  intake (PADI)  for this  chemical
 is 0.025 mg/kg/day.

 2.  The food uses evaluated  by the Tolerance Assessment System  (TAS)
were published tolerances  as established under 40  CFR  180.303,  and
pending  tolerances  that  are  under  consideration  by  the  Agency.

3.  A comparison of published  tolerances  to the PADI was conducted
using  the TAS Routine Chronic Analysis.  This analysis calculates a
Theoretical ,M.aximum  Residue Contribution  (TMRC)  based upon published
and pending'  tolerances. The  TAS analysis estimates dietary exposures
for the U.S. population average and  for each of 22 subgroups.  The
TMRC  for the  U.S.  population average  is 0.0132 mg/kg/day,  which
occupies  53.1%  of  the PADI.  The TMRCs for non-nursing  infants and
children 1-6  years of age exceeded  the  PADI:  0.0387 mg/kg/day  (155% of
the PADI)  and 0.0334  (135%  of the PADI),  respectively.

For children  1-6 years old and non-nursing  infants, the majority of
the TMRC was contributed by oranges  and apples,  which accounted for
70-80%  of the estimated exposure.  Since  the TMRC is  calculated, on  the
basis of tolerance-level  residues, it  is likely  that  data reflecting
actual  residue concentrations in these  commodities would  result in  a
lower estimate of dietary exposure.


                               17

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Summary of Current Oxamyl  Tolerances

                   	   Tolerances  (ppm)	(MRL)
Commodity         United Statesa/    Canadab/'   International  iloaexk/

Carrots                  0.1           —                0.1
Ginger                   0.1
Potatoes                 0.1           0.1                0.1
Sweet Potato             0.1           ---                0.1
Garlic                   0.1
Onion                    0.1           ---                0.05
Celery                   3.0           ---                3.0
Soybeans                 0.2           ---                0.1
Soybean Straw            0.2           —                —
Eggplant                 2.0           —                —
Peppers (Bell )            3.0           ---                3.0
Tomatoes                 2.0           ---                2.0
Cantaloupe               2.0           ---                2.0
Cucumbers                2.0           ---                0.5
Honeydew melon            2.0           —                2.0
Pumpkinsd/               2.0           —                —
Summer Squash            2.0           —                2.0
Watermelon               2.0           ---                2.0
Winter Squash            2.0           —                —
Citrus fruit group       3.0           —                3.0
Apples                   2.0           ---                2.0
Pears                    2.0
Bananas                  0.3           —                0.2
Cottonseed               0.2          ---                0.2
Peppermint hay          10.0           —                —
Spearmint hay           10.0           —                —
Peanuts                  0.2           ---                O.le/
Peanut hay A forage      2.0           ---                2.0
Pineapples               1.0           —                1.0
Pineapple forage        10.0          ---                ---
Pineapple branf/     6.0              —•                —
a/ The  U.S.  tolerance  definition does not include theoximeeven
   though  the U.S. tolerance  level is based upon combined levels of
   oxamyl  and   its oxime combined.
b/ The Canadian tolerances are expressed in terms of oxamyl  per  se.
c/ The Codex Maximum Residue  Levels are expressed as residues~~of~~oxamyl
   and its oxime, expressed as oxamyl.
d/ Although this crop has a tolerance there are  no  EPA  registered  uses.
e/ Available U.S. data indicate  that  residues  of oxamyl  and  its  oxime
   in or   n peanuts will not  exceed 0.1 ppm.
f/ Feed Additive Tolerance (21 CFR 561.285)
                                18

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           IV.   REGULATORY  POSITION AND RATIONALE


A. SUMMARY OF REGULATORY  POSITIONS AND RATIONALES


    1.  Special Review

The Agency is not placing oxamyl into Special Review  at  this time.

Rationale;

Calculations and  models based upon the acute  toxicity of  oxamyl
indicate that  granular formulations  of oxamyl have the  potential to
cause effects (i.e. non-target mortality)  in  birds and mammals, and
certain uses may exceed  special review criteria.   There  is, however,
'only  limited  field data  to support the  finding that  significant
adverse  effects  exist  for  terrestrial  wildlife.   The Agency  is
requiring  extensive  field monitoring data  to define  the extent of
exposure and hazard.   Evaluation of the necessity  for  a  special review
on oxamyl will  be  completed  after acceptable  data have been  received
and reviewed.

Incident data and human toxicity data on file indicate that systemic
poisoning to users and/or field workers  can result from exposure to
oxamyl.   Through the continued Restricted Use Classification of SC
formulations, and the imposition of protective clothing  and equipment,
work  safety  and reentry  statements,  on all end-use product labels  the
Agency believes that hazards  posed by acute toxicity will be mitigated.


     2.  Restricted Use Classification

All  oxamyl  end-use  products  are  candidates  for restricted  use
classification based upon toxicity to avian and mammalian species.   In
addition,  the Agency will continue to restrict the 24%  SC formulation
of oxamyl on the basis of acute toxicity.  Registrants of 10G  products
have the option of either submitting  the  acute toxicity data described
in Table C or also classifying these products for restricted use on
the basis  of  acute toxicity.  (Note:  Submitted data may  indicate
continued restricted use classification).

Rationale:
All registered oxamyl  products  bear  outdoor  uses  that  may pose risks
to non-target birds and mammals.   All  products  are  classified for
Restricted Use because residues per square foot occurring immediately
after application in or on the food  of  avian and mammalian species
exceed 1/10 the dietary LD50.
                               19

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Available data  indicate that the 24%  SC  formulation should continue to
be restricted.  These   data indicate that the technical product is
extremely toxic via the oral and inhalation routes of administration.
These data are  sufficient to indicate that  the 24% SC formulation will
meet  or  exceed the  acute toxicity criteria  for  restricted use
classification.  Extrapolation of the  existing data base to the 10G
formulation  also indicates  that these formulations are likely to
exceed the criteria for restricted use classification.   However, due
to the nature of granular formulations, it is possible  that certain
products  will  not  exceed  the  criteria  for   restricted  use
classification.  Registrants are therefore  being  given the opportunity
to  develop  and  submit  acute  toxicity data that  will permit
determination of the  appropriate  toxicity  categories  and restricted
use wording  for 10G products.  Registrants may  choose not to submit
these data and  additionally classify  these  products for restricted use
on the basis  of acute  toxicity.


3.Endangered  Species

Endangered species  labeling  has  been  required through PR Notices 87-4
and 87-5 issued May 1,  1987.

Rationale:
Oxamyl  is toxic to  certain species of  .fish,  birds,  mammals,  and
aquatic invertebrates which  reside in areas  where  oxamyl  is likely to
be used.  The Agency,  in an attempt  to limit use of  oxamyl  in areas
where its use may  be detrimental to  endangered species,  has required
through  Pesticide  Registration  (PR) Notices    endangered  species
information on  labeling of end-use products which contain uses for
certain crops.   The required labeling is  based on  Biological Opinions
by the Office of Endangered Species (OES)  of the  Fish  and Wildlife
Service,  U.S. Department of the  Interior.
4.  Reentry Interval

An  interim  48 hour  reentry  interval  is being imposed  for all
agricultural and greenhouse uses  of  oxamyl until such  time as the
appropriate reentry  data  have been submitted and evaluated.

Rationale:

Oxamyl use patterns  meet  or exce^' those criteria in Section 158.40 of
40 CFR concerning the require:.ant for a reentry  interval.   Oxamyl
meets these criteria in that:
                              20

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 1.  The acute dermal toxicity  of the technical  grade   is less than 200
 rag/kg.
 2.  The acute  oral  toxicity of the  technical grade is less than 50
 rag/kg.
 3.  The Agency has  received epidemiological  evidence  that residues of
 this  pesticide  can cause adverse effects  to individuals  entering
 treated sites.    There have been a number of poisoning incidents with
 oxamyl.

 Oxamyl also meets the exposure criteria of 40 CFR 158.140 in that it
 is  registered   for  use on  crops for  which  currer.- agricultural
 practices  include human tasks which  involve substantial  exposure to
 residues  of the pesticide.   A 48 hour reentry interval  is imposed
 because of  the high acute  toxicity of oxamyl and  data gaps  regarding
 post-application exposure.


 5.  Drift Studies Required

 The Agency is requiring  the  submission of drift studies for 24 SC
 formulations.

 Rationale:
 Because of reported occupational  illness  due  to  exposure to oxamyl as
 a  result  of  spray drift,  droplet  size spectrum  and drift field
 evaluation studies are required.


 6.  Groundwater Contamination  and Advisory Statements

 The  Agency  is requiring  the addition  of  a  groundwater  advisory
 statement to all oxamyl labels.

 Rationale:

 Oxamyl  leaches through the soil and has been found in ground water.
 At this time, because of the wide natural variability in  soil types,
 weather patterns and aquifer characteristics,  it  is impossible to
 specify those  circumstances  when  oxamyl  will reach groundwater. The
 ground  water data call-in of 5/31/84 was  initiated to derive that
 information which will allow  more accurate predictions concerning the
 potential of oxamyl to contaminate  ground water.  These data have been
 submitted and reviewed,  but found to be inadequate and additional
 information is  required  in this  standard. Acceptable  well-monitoring
 studies  do not indicate  toxicological  concerns from tip levels  of
 contamination reported at  this time. Oxamyl residues will oe monitored
 in the National Survey for Pesticides  in  Ground  Water. EPA Method 531,
 which measures both the parent and the oxime degradate, will  be used.
A pilot program for all the selected pesticides has begun.  Until the
 leaching  studies  and the data from the  pilot program have  been
 received and reviewed,  a Groundwater  Advisory Statement  is required on
 all oxamyl labels.


                               21

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          Rotation Restrictions Expanded

  A 6 month rotational  interval for crops  (including root crops)  for
which no  tolerance has been established,  must appear on all oxamyl
labels.

Rationale:
Residues  detected at 120 days in the confined crop rotation studies
indicate  that the existing rotational  crop interval of 4 months is
inadequate.   Extrapolation of these levels indicate that a 6 month
interval will be adequate.


8.   Glove Permeability Test Required

The  Agency is requiring a glove permeability test for the soluble
concentrate formulation of oxamyl.

Rationale:

Gloves  can greatly reduce dermal exposure and are  required  for
handling oxamyl SC products.   However, there are no data demonstrating
which   materials  adequately  limit dermal exposure.  The Agency is
requiring a glove  permeability  study  in order to  determine which
materials are best suited for  this use.


9.  Restrictions on Flaggers for  Aerial Application

The  Agency is prohibiting the use of human flaggers during aerial
application,  unless they are  in  an enclosed vehicle such as a pickup
truck or a tractor with a completely  enclosed cab.

Rationale:
The Agency is imposing  this requirement to minimize hazards to human
flaggers who inherently" face  a  risk  of exposure by direct contact or
drift during.aerial application.


10.  Changes in Precautionary Labeling

The  Agency will  require  that  end-use products  bear  updated
precautionary  labeling  (including protective  clothi."  and equipment)
related to  the toxicity category to which each prc iuct is assigned.
For the 24SC formulation,  these  statements (Toxicity  Category I)  are
required through  this registration standard.  For the 10G formulation,
the Agency will determine the appropriate labeling after review- of the
required toxicology data for  end-use products.
                               22

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Rationale:

Because of  the acute toxicity  of  oxamyl  products,   specific
precautionary statements are required  to prevent poisoning of workers
or  applicators  by direct  exposure  or contact  with  contaminated
clothing or materials.   Extrapolation of data from the technical  is
sufficient  to determine the  appropriate  precautionary labeling for the
24 SC product.  Registrants  of  10 G products have the option of either
utilizing  Toxicity  Category I precautionary  labeling and the
protective   clothing and   equipment    statements  described  under
P.L ?§2Hi£^^ L^k®.Lill2  in  this standard  or making  the appropriate
revisions after the submission of the required product specific  acute
toxicology  data.


11 .New Tolerances

No significant new tolerances or  significant new food uses will  be
granted until the Agency has received data sufficient to evaluate the
dietary exposure to oxamyl.

Rationale:
Residue chemistry and toxicology data  are  insufficient to assess the
adequacy of existing tolerances.  Animal metabolism,  field residue,
processing and  storage  stability  data  are required.    Pertinent
toxicology  data  gaps  include  chronic  toxicity,  oncogen ic i ty ,
teratogenicity,  reproduction,  and mutagenicity.   Refer to Appendix I,
Table A for  specific residue  chemistry and toxicology data  required.
A tolerance  reassessment cannot be completed until these data  are
submitted .
12. Labcj^njj  for Ha_za_rd_s  to  Non-target Organisms

Revised labeling for hazards to non-target organisms are  required.

Rationale:

Data indicate that oxamyl is highly toxic  to birds and mammals and
moderately toxic to aquatic organisms.   Other  data  indicate that
oxamyl  is moderately to highly toxic  to  the  honeybee. Precautionary
label statements  relative to the  potential  exposure of  non-target
organisms to oxamyl will provide use information to  promote practices
to limit such non-target exposure.
                               23

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13.  Use Directions Nursery and Ornamental  Plants

Use directions for nursery and ornamental  plants must be revised to
prohibit applications of oxamyl in domestic situations (such  as to
potted plants  or  interior plantscapes in or  around homes, shopping
malls, or commercial  buildings).   This statement is required through
this  Registration Standard  for  the 24  SC.  For 10G products, the
registrants have the option of adding this  statement immediately or
submitting  the acute toxicity  data in  Table  C for Agency  review.
(Note:  Submitted data may indicate the statement  is  required)

Rationale:
The high  acute toxicity  of oxamyl  24  SC formulations creates an
unacceptable  risk  if existing formulations are applied  in such areas
especially  if frequented  by children.   Extrapolated   data would
indicate  that 10G  formulations may also pose an unacceptable risk in
these  situations.   However,  due  to  the  nature  of  granular
formulations,  it possible  that these  products may  not pose  such
unacceptable  risk.  Registrants of 10G products therefore  have the
option  of submitting the appropriate acute toxicity data to evaluate
such potential risk  or choosing not to submit  such data and including
the prohibition.


14.  Continuation of  Registration

While the required data are under development, currently registered
manufacturing use  products  (MPs) and end use products (EPs) containing
oxamyl  as the  sole active ingredient  may  be  sold,   distributed,
formulated and used,  subject to  the terms  and conditions  specified in
this Standard.   Registrants  must provide  or  agree  to develop
additional data,  as specified  in  the  Data Appendices,  in order to
maintain existing  registrations.

Rationale:   Under  FIFRA,  the Agency  may choose  not to  cancel or
withhold registration 'if data are missing or are inadequate  (see  FIFRA
sec. 3(c)(2)(B) and 3(c)(7)).  The issuance of this  sta'ndard provides
a mechanism for identifying data needs.   These data will be reviewed
and evaluated, after which the Agency will  determine if additional
regulatory actions are necessary.
                              24

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B. CRITERIA FOR REGISTRATION


To be  registered  or  reregistered under this  Standard,  manufacturing-
use (MP)  and end-use  (EP) products must contain oxamyl as the  sole
active ingredient, bear required labeling,  and conform  to the  product
composition,  acute  toxicity limits,  and use pattern requirements
listed in this document.

The applicant for registration or  reregistration  of MP and/or EP
products  subject to this  Standard must  comply with  all terms and
conditions  described,   including submission  of  an  up-to-date
Confidential  Statement of Formula,  submission of revised labeling,
commitment to fill  data  gaps on the schedules  as  specified by the
Agency and,  when applicable,  offer  to pay  compensation  as required by
sections 3(c)(l)(D)  and  3(c)(2)(D)  of  the Federal  Insecticide,
Fungicide,  and  Rodenticide  Act (FIFRA),  as  amended,  7  U.S.C.
136(c)(l)(D)  and 136(c) (2 ) (D) .   Registrants of end-use products who
qualify for the Formulator's  Exemption must submit five  (5) copies of
draft labeling incorporating the unique label statements identified in
Section D.
                               25

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C. ACCEPTABLE RANGES AND LIMITS


    1.  Product Composition  Standard

To conform to  this  standard, MP  and  EP   products must  contain oxamyl
as  the  sole  active  ingredient.    Each formulation proposed for
registration  must be fully  described  with an appropriate certification
of limits,  stating maximum and minimum amounts  of the active and
intentionally added inert ingredients present  in their products, as
well as  impurities  found at levels greater  than  0.1%.


    2.   Acute Toxicity Limits

The  Agency   will  consider  registration  of  technical  grade,
manufacturing-use,  or end-use products containing oxamyl,  provided the
product  is   supported  by  appropriate acute  toxicity data and the
labeling for  the product bears  appropriate precautionary  statements
for the toxicity category in which the product is placed.    Oxamyl MPs
and  24SC end-use  products  are in toxicity  category  I  and the
appropriate signal  word  is  DANGER.


    3.  Use  Patterns

To be registered under  this Standard,  manufacturing-use products must
be labeled for formulation into  other manufacturing-use  products or
into end-use  products  bearing  federally  registered uses. End-use
products must  bear  federally registered uses.  Appendix III lists all
federally registered uses as  well  as approved maximum application
rates and frequencies.
                               26

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 D. REQUIRED LABELING


 All  products must bear appropriate labeling as specified in  40  CFR
 162.10,  PR  Notices 83-2, 83-3,  87-4,  87-5,  and below.  Appendix II
 contains further information on label requirements.

 Pesticide products containing oxamyl as the active ingredient may not
 be released for shipment by the registrant after August  1,  1988 unless
 the  product  bears  amended labeling  which complies  with  the
 requirements of this standard.

 Pesticide products containing oxamyl as the active ingredient may not
 be   distributed,  sold,  offered  for  sale, held  for  sale, shipped,
 delivered  for shipment,  or received  and (having been so received)
 delivered  or offered to be  delivered by any person after August 1,
 1989 unless  the  product  bears amended labeling  which  complies  with
 the  requirements of this Standard.

 Labeling for the protection of endangered species are required as per
 PR Notices 87-4 and 87-5  issued May  1,  1987.


 All  Products

     1.  Ingredients Statement

 Registrants of all oxamyl products  are  required  to  revise their labels
 to the following format:

     ACTIVE INGREDIENT:

     Oxamyl  Methyl N'N•-dimethyl-N-[(methylcarbamoyl)oxy]-
             1-thiooxamimidate	     %
     INERT INGREDIENTS:		% -


Manufacturing Use Products
                           9

     1.  Use Pattern Statements

All  manufacturing-use  oxamyl  products  must  state that  they are
intended for formulation  into  ^ther MPs or end-use products for  uses
accepted by  the  U.S. Environmental Protection Agency.  The labeling
must specify those use patterns  listed  under Use Patterns  as Appendix
III.   No uses may be  included  on any  label where the  registrant fails
to agree  to comply  with the  data  requirements in TABLE A for  that
pattern of use.
                               27

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     2.  Environmental  Hazards

The  following  revised environmental  hazard statement must appear on
all MP labels:

"This pesticide is toxic  to  wildlife.  Do not discharge  effluent
containing this product into lakes,  streams,  ponds,  estuaries,  oceans
or public  waters  unless  this  product  is   specifically  identified and
addressed in an NPDES permit.   Do not discharge effluent containing
this product to sewer systems without previously notifying the  sewage
treatment plant authority.   For guidance contact  your State Water
Board or Regional  Office  of the  EPA."


      3.Protective Clothing and  Equipment

The following statement must appear on the Manufacturing Use Product:

"HANDLE THE CONCENTRATE  ONLY WHEN WEARING THE  FOLLOWING PROTECTIVE
CLOTHING AND EQUIPMENT:

Wear a protective suit of one or two  pieces that  covers all  parts of
the body  except the head,  hands,  and  feet.  Wear  chemical resistant
gloves,  chemical -resistant apron, and chemical resistant shoes,  shoe
coverings, or boots.   Wear goggles or  a face shield.   Wear a pesticide
respirator approved by the National  Institute  for  Occupational  Safety
and Health (NIOSH) and  the Mine Safety  and Health Administration
(MSHA)."


End Use  Products

1.Environmental  Hazards  Statements

    a.   Oxamyl  24% SC

 "This pesticide  is  toxic to  wildlife and  aquatic invertebrates.
Drift and runoff may be hazardous to aquatic  organisms  in neighboring
areas.   Do not  apply  directly to water or wetlands  (swamps,  bogs,
marshes,  and potholes).    Do  not contaminate water  by cleaning  of
equipment or disposal of  wastes."


    b.   Oxamyl  10% G

"This product  is  toxic t^ wildlife.  Cover, collect, or   incorporate
granules  spilled on soil -surfaces.  Do not  contaminate water by
cleaning  of equipment or  disposal of   wastes."
                               28

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2.  Required Bee Caution

    a.  Oxamyl 24% SC:

"This product is  highly  toxic to bees exposed to direct   treatment or
residues  on  blooming crops or weeds.  Do not  apply this product or
allow to  drift to  blooming   crops  or  weeds  if  bees  are  visiting the
treatment  area."


3.  Special Precaution for Ornamental  and Potted Plants:

    a. Oxamyl 24% SC:

The  following  statement must  appear  in  the  directions  for use
concerning ornamental and potted plants:

"For use only in commercial greenhouses and nurseries.  Do not apply
this  product to  interior plantscapes or  potted plants  in or around
domestic  areas  such as homes,  shopping malls,  or  commercial
buildings."

    b. Oxamyl 10% G:

The above statement regarding ornamental or potted plants must appear
on  the label or the registrant may submit the  acute toxicity data  in
Table C.  to determine if  such statement is  not appropriate.


4.Reentry Statement:

The following statement must appear on the  labeling of agricultural
end use products which are applied to crops whose culture may involve
hand labor tasks:

" Do not enter treated areas for  48 hours after application unless
protective clothing is worn,  as  described  in  the  product  labeling"
                               29

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  5.  Restricted  Use Statement

  The following restricted use statement must  appear  on  the  front panel
of all 24 SC products.   This statement must also appear on 10G labels
unless the  acute  toxicity data (in Table C)  indicate  that the product
is not a  candidate for restricted use on the basis of acute toxicity.
In such cases,  "Acute Toxicity And" may be deleted from the statement.

                      "RESTRICTED USE PESTICIDE
                        Due to Acute Toxicity
                  And Toxicity to Birds and Mammals

For retail  sale to and use only by certified applicators or persons
under their direct supervision and only for those uses covered by the
certified applicator's certification."


6c Rotational Crop Statement

All end use products must have the following crop rotation statement:

"Do not plant crops other than those  with  registered  oxamyl  uses
within  6 months  after  the  last  application."
                               30

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"7.   Protective Clothing and Work Safety

    a. All Products.

"WEAR THE FOLLOWING PROTECTIVE CLOTHING AND EQUIPMENT DURING HANDLING,
MIXING,  LOADING,   APPLICATION, EQUIPMENT AND CLEANING, DURING EARLY
REENTRY TO TREATED AREAS, AND DURING DISPOSAL OF THE  PESTICIDE:

Wear a protective suit of one or two pieces that covers all parts of
the body except the head,  hands,  and feet.  Wear chemical-resistant
gloves,  chemical-resistant  apron,  and chemical resistant shoes,  shoe
coverings  or boots.   Wear goggles or faceshield and  a pesticide
respirator approved by  the  National  Institute  for  Occupational Safety
and  Health  (NIOSH)  and/or  the  Mine Safety  Health  Enforcement
Administration  (MSHA).   A chemical resistant hat or hood must be worn
if the application is  likely to result in overhead exposure, such as
during air blast  applications.

During application  from a  tractor with a completely enclosed cab or
aerially with an  enclosed cockpit,  a long  sleeve shirt and long legged
pants may be worn in place  of the above protective  clothing.  Chemical
resistant gloves  and an approved  respirator must be available in the
cab or cockpit, and the gloves must be worn when exiting.  Note that
this clothing is  inadequate to protect you during equipment repair,
equipment cleaning, reentry, or during pesticide disposal.

IMPORTANT!   Always wash hands,  face  and arms with soap a-nd water
before eating, smoking, drinking or toileting.

AFTER WORK:  Wash  gloves with'soap  and water before removing. Take off
all clothing and  shoes.  Shower using soap and  water.  Wear only clean
clothes.   Do not  use contaminated  clothing.  Wash  protective clothing
and  equipment  with soap  and  water after  each use.   Personal and
protective clothing worn during use  must  be laundered separately from
household  articles.    Clothing  and  protective  equipment  heavily
contaminated  or drenched with  oxamyl  must be  destroyed according to
state and local regulations.
                       <.
HEAVILY  CONTAMINATED  OR   DRENCHED  CLOTHING  CANNOT  BE  ADEQUATELY
DECONTAMINATED.

Respirators  should be  cleaned and cartridges replaced according to
instructions  included with  the respirator.  Replace gloves  frequently.

DURING  AERIAL  APPLICATION,  HUMAN FLAGGERS  MUST  BE   IN A  TOTALLY
ENCLOSED VEHICLE."
                               31

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    be   For the 24 SC only,  the following wording may appear on the
label:
"If mixing or loading  the  concentrate with a closed  system,  a long
sleeve  shirt and  long-legged  pants  may  be  substituted for  the
protective suit  and respirator.   Appropriate protective clothing and
equipment must  still be  worn during application,  equipment   repair,
equipment cleaning,  early reentry, and disposal."
8.Ground Water  Advisory

The following statement is required for all end-use  products.
it
                       GROUND WATER ADVISORY

Residues of  (product name) can  seep  or leach through  soil and can
contaminate ground water which may be used for drinking.  Users are
advised not to  apply (product name) where  the water table  is close to
the surface and  where soils are very permeable,  i.e.,  well-drained
soils such as loamy  sands. Local Agricultural  Agencies  can provide
information  on the soil types i-n your  area and  the location of the
ground water.    "
                              32

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            V.  PRODUCTS  SUBJECT TO THIS STANDARD

All products containing one or more of the pesticides identified in
Section II.A.  are subject to certain requirements for data submission
or changes in composition, labeling or packaging  of  the product.  The
applicable  requirements depend  on whether the  product  is  a
manufacturing or end use product  and whether the pesticide is the sole
active ingredient or one of multiple active  ingredients.

Products are subject to  this Registration Standard as follows:

A. Ma^uf_ac_t.ur.ing_use_pro_du_ct_s  containing oxamyl  as the sole  active
ingredient are subject to:

     1.  The restrictions (if  any) upon use, composition,  or
     packaging listed in Section  IV,  if they pertain  to  the
     manufacturing use product.

     2.  The data requirements listed  in Tables A and B.1

     3.  The labeling requirements specified for manufacturing
     use products in Section IV.

     4.  Administrative  requirements  (application forms, Confiden-
     tial Statement of Formula, data  compensation provisions)
     associated with reregistration.
1 Data requirements are listed in the three tables  in Appendix I  of
this registration standard.   The guide to tables in that Appendix
explains how to read  the Tables.

Table A lists  generic data requirements applicable to all products
containing the pesticide subject to this  registration standard.   Table
B  lists  product-specific data  applicable   to  manufacturing  use
products.   The data  in Tables A and B need  not  be submitted by a
producer  who  is  eligible for the  formulator's exemption for that
a,'ive  ingredient.

Table C lists  product-specific data  applicable to end use products.
                               33

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 B. Ma_nu^c^ur_inc[_u_se_p_roduct£  containing oxamyl  as  one of •
 multiple active ingredients are  subject to:

 The  data  requirements listed in  Table A and labeling requirements
 specified for manufacturing use  products.

 C.  End_use_p_roducts containing  oxamyl  as the  sole active
 ingredient  are subject to:

 1.  The restrictions (if any)  upon use,  composition, or  packaging
 listed in Section IV if they  pertain to the end use product.

 2.  If eligible for  the formulator's exemption2,  the data requirements
 listed in Table C.

 3.   If not  eligible  for the  formulator's  exemption,  the  data
 requirements listed in Table A and the data requirements listed in
 Table C.

 4.   The labeling  requirements  specified for end use products in
 Section IV.
     * solvents or diluents must be declared as inerts.  The
Agency does not have  data  indicating that these solvents are
insecticidal.

 If you purchase  from another producer and use as the source of your
active ingredient only EPA-registered products,  you are eligible for
the formulator's  exemption for generic data  concerning  that active
ingredient (Table A) and product-specific data for the  registered
manufacturing use product you  purchase  (Table  B).

Two circumstances  nullify  this  exemption:

1)  If you  change sources of  active ingredient to an unregistered
product,  formulate your  own active ingredient,  or acquire  your active
ingredient form  a firm  with  ownership in common with  yours,  you
individually  lose the  exemption and  become subject to  the  data
requirements in Table A.

2)   If no producer subject to the generic data  requirements in Table A
agrees to  submit the required data, all end  use producers lose the
exemption,  and become subject to those data  requirements.
                               34

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D.   End_uj5e_£r;oduc;t£  containing  this pesticide  as one of multiple
active ingredients are subject to:

a.    If not  eligible  for the  formulator's  exemption,  the  data
requirements listed  in Tables A  and  C.

b.   If eligible for  the  formulator's  exemption,  the data requirements
listed in Table C.

c.   The labeling requirements specified for end use products specified
in Section IV.
                                35

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           VI.  REQUIREMENT  FOR  SUBMISSION OF GENERIC DATA

This portion of the Registration Standard is a notice issued under the
authority of FIFRA sec.  3(c)(2)(B).  It refers to the data  listed in
Table A, which are required  to be submitted by registrants to maintain
in  effect  the  registration of   products  containing  this active
ingredient.


A.  What are generic data?

Generic data pertain to the properties or effects of a particular
active  ingredient.  Such data  are relevant to an evaluation of all
products containing that active ingredient regardless of  whether the
product contains other ingredients,  (unless the product bears labeling
that would make the data requirement inapplicable).

Generic data may also be data on a  "typical  formulation" of  a product.
"Typical formulation"  testing is often required for ecological effects
studies and applies to all products having  that formulation  type.
These are classed as generic data,  and are contained  in Table A.


B.  Who must submit generic  data?

All current registrants  are  responsible for submitting generic data  in
response  to  a  data request  under  FIFRA sec.  3(c)(2)(B)  (DCI Notice).
EPA has decided, however, not to require  a  registrant who  qualifies
for the formulator's exemption  (FIFRA sec.  3(c)(2)(D) and  }  152.85)  to
submit  generic data in response  to a DCI notice if the registrant who
supplies-the active ingredient in his product is complying with the
data request.

     If you are not now  eligible for  a formulator's exemption,
you may qualify for one  if you change your source of  supply
to a registered source that  does not  share ownership  in
common with your firm.   If you choose to change sources of
supply,  the Confidential  Statement  of Formula  must identify
the new source(s)  and you must submit a Formulator's  Exemption
Statement form.
3  Registrations  -ranted after  issuance of  this Standard  will be
conditioned upon submission or citation of the data  listed in this
Registration Standard.
                               36

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 If  you apply  for  a  new registration  for products containing this
 active ingredient after the issuance of this Registration Standard,
 you will  be required to submit or cite generic data relevant to the
 uses of your product if,  at  the time the application is  submitted, the
 data have been submitted to  the Agency by current registrants.   If the
 required data  have•not yet  been submitted, any new  registration will
 be conditioned upon the  new  registrant's submission or  citation  of the
 required data  not  later  than  the  date upon which  current  registrants
 of similar  products are required  to provide such data.   See FIFRA sec.
 3(c)(7)(A).   If you thereafter fail to comply with the condition of
 that registration to provide data, the registration may be canceled
 (FIFRA  sec.  6(e)) .


 C.  What generic data must be  submitted?

 You may determine which generic  data you must submit by consulting
 Table A.  That table lists the generic data needed to evaluate current
 uses of all products  containing this active  ingredient, the uses for
 which  such  data are required,  and the dates by which the data must be
 submitted to the Agency.


 D.  How to comply  with PCI requirements.

 Within 90 days of  your receipt of  this Registration Standard, you must
 submit to* EPA a completed  copy of  the  form  entitled "FIFRA Section
 3(c)(2)(B)  Summary  Sheet" (EPA Form 8580-1,  enclosed) for each of your
 products.   On that form you  must state which of the  following six
 methods you will use to  comply with the DCI requirements:

 1.  You will submit the  data yourself.

 2. You  have  entered into an  agreement with one or more  registrants
 to jointly develop (or share in the  cost of developing)  the data,
 but will not be submitting the data yourself.   If you use this  method,
 you must state who will  submit the data on which you will rely. You
 must also provide EPA with  documentary evidence that an agreement has
 been formed which allows you to rely upon the data to be submitted.
 Such  evidence may  be:   (1) your letter  offering to  join  in an
 agreement and the other registrant's acceptance  of your offer, (2)  a
 written statement by the parties that  an agreement exists, or (3)  a
 written statement  by  the person who will be  submitting the data that
 you may rely  apon its  submission.  The  Agency  will also require
 adequate  assurance that the  person whom you sta .« will  provide the
data is taking appropriate  steps  to  secure  it.   The agreement  to
produce the data  need not specify all  of  the  terms of the final
arrangement between the  parties or a mechanism to  resolve  the terms.
                               37

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 3.  You have attempted to  enter  into an agreement to jointly
 develop data, but no other registrant has accepted your offer.
 You request that EPA not suspend your registration for non-compliance
 with the PCI.  EPA has determined that,  as a general policy, it will
 not suspend  the  registration of a product when  the  registrant has in
 good  faith  sought and  continues  to seek to enter into  a  data
 development/cost sharing program,  but the other registrants developing
 the  data  have refused to accept its  offer.   [If your  offer is
 accepted,  you may  qualify for Option 2 above  by  entering into an
 agreement  to supply the data.]

     In order to qualify for this method, you must:

 a.  File with EPA a completed "Certification  of  Attempt to Enter  into
 an Agreement with other Registrants  for Development  of  Data" (EPA  Form
 8580-6,   enclosed).

 b.  Provide  us with a copy  of your offer to  the other  registrant and
 proof  of the  other registrant's receipt of your  offer (such as  a
 certified  mail receipt).  Your  offer must, at a  minimum,  contain the
 following  language or its  equivalent:

     [Your company name] offers  to share in the burden of
     producing the data required pursuant to  FIFRA sec.
     3(c)(2)(B) in the [name of  active  ingredient] Registration
     Standard upon terms to be agreed or failing agreement
     to be bound by binding arbitration as provided by FIFRA
     section 3(c)(2)(B)(iii).

 The remainder  of your offer may not in any way  attempt to limit  this
 commitment.   If  the other registrant to whom your  offer is  made  does
 not accept your offer,  and if the other registrant informs us on a DCI
 Summary  Sheet  that  he  wil'l  develop and submit the data required under
 the DCI, then  you  may qualify  for this option.  In  order for you  to
 avoid suspension under this method,  you may  not  later withdraw  or
 limit your offer to share  in the burden of  developing the data.   In
 addition, the other registrant must fulfill  its  commitment to develop
 and submit the data.

 4.  You request a waiver of the  data requirement.   if you  believe that
 a data requirement does not (or should not)  apply to your product or
 its uses, you must provide EPA with a statement of the reasons why you
believe  this  is so.   Your  statement  must  address  the specific
composition or use factors that  lead you to believe that a requirement
does  not  apply. Since the Agency has  car^./ully considered  the
composition and uses of pesticide products in determining that a data
requirement applies, EPA does not anticipate  that many waivers will be
granted.   A  request for waiver does not extend the time-frames for
developing required data,  and if your  waiver request is denied,  your
registration may be suspended  if you  fail  to  submit  the data.
                               38

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 5. You request that EPA amend your registration  by deleting the
 H§^§_^2^;_whJ:ch_t;he_da/ta_a^;e_needed_._  You are  not required to submit
 data for uses which are no longer  on  your label.


 6.  You request voluntary  cancellation of the registration of your
 product(s)  for which the data are needed.


 E.  Procedures for requesting a change in testing protocol.

 If you will generate the required data and plan  to use test procedures
 which  deviate from (or are not specified in) either EPA's Pesticide
 Assessment Guidelines or the Reports  of  Expert Groups to the Chemicals
 Group, Organization for Economic  Cooperation and Development (OECD)
 Chemicals  Testing  Programme,  you must submit for  EPA  approval the
 protocols you propose  to use.

 You should  submit your protocols  before beginning testing and await
 EPA  approval,  because the  Agency  will not  ordinarily  accept as
 sufficient studies using unapproved protocols.  A request  for  protocol
 approval will not extend the timeframe for submission of  the data, nor
 will extensions generally  be given to conduct studies due  to submittal
 of inappropriate protocols.


 F.  Procedures for requesting extensions of time.

 If you think that you  will need more  time to generate the data than is
 allowed by  EPA's schedule, you may submit a request for an extension
 of time.  Any request for  a time extension which is made  as an initial
 response to a section 3(c)(2)(B)  request notice must be  submitted in
 writing to  the Product Manager listed at  the end of this section and
 must be made before the deadline  for response.  Once dates have been
 committed to  and EPA  has  accepted these commitments, any  subsequent
 requests for  a  time extension  must be submitted in writing to the
 Office of Compliance Monitoring.

 EPA will view failure to request an extension before  the response
 deadline as a waiver  of any future  claim  that  there was  insufficient
 time to submit  the data.   While EPA  considers  your  request,  you  must
 strive to meet the deadline  for  submitting the  data.

The extension request  should state the reasons why you believe that an
 extension  is necessary and the  steps you  have taken  to meet the
 testing deadline.   Time extensions normally  will not be granted due to
problems with laboratory capacity or adequacy of funding, since the
Agency believes  that with  proper planning these can be overcome.   Time
extensions  may be  considered when joint data development is  planned,
or when the Agency  must approve a new or modified protocol before the
study can be begun.
                               39

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A request  for an extension  does not  extend  the timeframe  for
submission of  the  data.  If  EPA denies  your request for  a  time
extension  and  you do not submit the data as requested, EPA may begin
proceedings to  suspend  the  registrations of your products.


G.  Existing stocks provision upon suspension or cancellation—

The Agency has determined that  if a  registration  is  suspended for
failure to respond  to  a DCI  request under  FIFRA sec.  3 (c) (2) (B)-, an
existing  stocks  provision  is  not  consistent  with  the  Act.
Accordingly, the Agency does not anticipate granting permission to
sell or distribute existing stocks of suspended product  except  in rare
circumstances.   If you  believe  that your product will be suspended or
canceled and that an existing stocks provision should be granted, you
have the burden of clearly demonstrating to  EPA  that granting such
permission  would  be   consistent  with  the  Act.   The  following
information must be included  in any request  for an existing stocks
provision:

     1.   Explanation of  why an  existing stocks provision is
     necessary,  including a statement of the  quantity of
     existing stocks and your estimate of the time required
     for their  sale or distribution; and

     2.   Demonstration that such a provision  would be consis-
     tent with  the provisions of FIFRA.
                               40

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   VII.  REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA

Under its  DCI authority,  EPA has  determined  that certain product-
specific data are  required  to maintain your registrations in effect.
Product-specific  data are derived from  testing  using  a specific
formulated product, and,  unlike  generic  data,  generally  support  only
the registration of that product.  All  such  data  must be  submitted  by
the dates specified in this Registration  Standard.

If you  have  a manufacturing use product,  these data are listed  in
Table B.  If  you have  an end use  product, the data are listed in Table
Co  As  noted earlier,  the  Agency has decided  that it  will not
routinely require  product-specific data  for  end  use products  at  this
time.  Therefore,  Table C may not be contained in this Registration
Standard;  if there is no Table C, you  are not  required to submit the
data at  this time.

In order to comply with the product specific data requirements, you
must follow the same  procedures as for generic data.  See  Section  IV.D,
E, F,  and G.   You should note, however,  that product chemistry  data
are required for every product, and the only acceptable responses are
options   IV.D.I.   (submit  data)  or  I V.D . 6 . ( cance11 ation  of
registration).

Failure  to comply with the product-speci'fic  data  requirements for your
products will result  in  suspension of  the product's registration.
                               41

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    VIII.  REQUIREMENT  FOR SUBMISSION OF REVISED LABELING

FIFRA requires each product  to  be  labeled  with accurate,  complete and
sufficient  instructions  and precautions,  reflecting the Agency's
assessment of the  data  supporting the product  and  its  uses.   General
labeling requirements  are set out in 40 CFR 162.10  (see Appendix II -
LABELING and SUMMARY).   In addition,  labeling requirements specific to
products containing this pesticide are specified  in Section IV.D of
this Registration Standard.  Applications  submitted  in response to
this notice  must include draft  labeling for Agency review.

If you fail to submit revised labeling as required, which complies
with 40 CFR 162.10 and the  specific  instructions  in Section  IV.D., EPA
may seek to cancel  or  suspend  the registration of  your product  under
FIFRA sec. 6.
                               42

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                   IX.   INSTRUCTIONS FOR SUBMISSION

A. Manufacturing Use Products  (MPs) containing Oxamyl as sole active
ingredient.

1. Within 90 days from  receipt of this document,  you must submit to
the  Product Manager  in the  Registration Division  for each  product
subject to this Registration  Standard:

        a.  The "FIFRA Section 3(c)(2)(B)  Summary  Sheet" (EPA
            Form 8580-1),  with appropriate attachments./4

        b.  Confidential Statement of Formula (EPA Form 8570-4),
            attached separately.

        c.  Formulator's Exemption Statement, if applicable.

        d.  Evidence of compliance with data compensation
            requirements of FIFRA sec. 3(c)(1)(D).   Refer  to 40 CFR
            152.80-152.99.

2. Wi.^hiLji_9_montJ}s from receipt of this  document you must submit to
the Product  Manager:

        a.  Two copies  of any required product-specific data
            (See Table  B).

        b.  Five (5) copies of draft labeling, including the
            container label and any associated supplemental  labeling.
            Labeling should be either typewritten text  on  8-1/2 x  11
            inch paper or a mockup of the labeling suitable  for
            storage in  8-1/2 x  11  files.   The draft  label  must
            indicate the intended colors of the  final  label,  clear
            indication of the  front  panel of  the label,  and the
            intended type sizes  of the  text.

        c.  Product Specific  Data Report.
4  If on the Summary Sheet,  you commit to develop the data, present
arguments that a  data requirement is not applicable or should  be
waived,  or submit  protocols  or  modified protocols  for Agency review,
you  must  submit  a copy  of  the Summary Sheet  (and  any supporting
information)  to the Office of Compliance Monitoring, which will  be
monitoring  the  data rrenerated in response  to this notice.    This
submission  is in addi^on to responding to the Product Manager, and
should be submitted to the  Office of Compliance  Monitoring  at the
address  given at the end  of  this section.  (Actual  studies are  not  to
be submitted to the Office of Compliance Monitoring.)
                               43

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3. Within the times  set  forth in Table  A,  you must  submit to the
Registration Division all generic data, unless you are eligible for
the formulator's exemption.   If for any reason  any  test is  delayed or
aborted  so  that the schedule cannot be met, immediately notify the
Product  Manager and the  Office  of  Compliance  Monitoring of the
problem,  the reasons for  the problem, and  your  proposed course of
action.

B. Manufacturing Use Products containing Oxamyl in combination with
other active ingredients.

1.  Within  90 days  from receipt of  this  document,  you must submit to
the Product Manager in the  Registration Division:

        a.  FIFRA sec.  3(c)(2)(B)  Summary Sheet, with appropriate
            attachments    (EPA Form  8580-1).

        b.  Confidential Statement of Formula (EPA Form 8570-4),
            attached separately.

        c.  Formulator's Exemption Statement, if applicable.

2.  Within 9 months from receipt of  this document you must submit five
(5)  copies of draft labeling.

3.  Within  the  time  frames set  forth in  Table A, you must submit to
the Registration Division all generic data, unless you are  eligible
for the formulator's exemption.  If  for any reason any  test is delayed
or aborted so that the schedule cannot  be met,  immediately notify the
Product  Manager and the  Office  of   Compliance  Monitoring  of  the
problem,  the reasons for  the problem,  and  your proposed course of
action.

C.  End Use Products containing Oxamyl  alone  or  in combination with
other active ingredients.

1. WrthAj}_2£_day^ from receipt of thi.s document,  you must submit to
the Product Manager in the  Registration Division:

        a.  FIFRA Section  3(c)(2)(B) Summary  Sheet, with
            appropriate attachraentsS  (EPA  Form  8580-1).

        b.  Confidential Statement of Formula (EPA Form 8570-4),
            attached separately.

        c.  Formulator's Exemption Statement, if applicable.
                               44

-------
2.   Within 9 months from receipt of this document you must submit
to the Product Manager:

        a.   Two copies of any  product-specific data, if required
            by Table C.

        b.   Product Specific Data Report, if Table C lists
            required product-specific data.

c.   Five copies of draft labeling, including the container label and
any associated supplemental  labeling.   Labeling should be either
typewritten text on 8-1/2 x 11 inch paper or a mockup of the labeling
suitable for storage in 8-1/2 x  11  inch files.  The draft  labeling
must indicate the intended  colors  of  the  final  label, clear indication
of the front panel of the  label,  and the intended type sizes of the
text.   End  use product labeling  must comply  specifically  with the
instructions in Section IV (Regulatory  Position and Rationale).
E. Addresses

     Dennis Edwards
     Product Manager 12
     Registration Division (TS-767C)
     Office of Pesticide Programs
     Environmental Protection Agency
     401 M St.,  SW
     Washington,  D.C.   20460

     The address for submissions to the Office  of  Compliance
     Monitoring is:

     Laboratory Data Integrity Program
     Office of Compliance Monitoring  (EN-342)
     Environmental Protection Agency
     401 M St.,  SW
     Washington,  D.C.  20460.
                               45

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   APPENDIX I
DATA APPENDICES
         46

-------
                              GUIDE TO TABLES

  Tables A,  B,  and C contain  listings of data  requirements  for  the
 pesticides covered by this Registration  Standard.

      Table A contains generic data  requirements that apply to
      the pesticide in all  products,  including data requirements
      for which a "typical  formulation" is the test substance.

      Table B contains product-specific data requirements that
      apply only to a  manufacturing  use product.

      Table C contains product-specific data requirements that
      apply only to an end  use product.

 The data tables  are  generally organized according to the following
 format:

 1.   Data Requirement  (Column 1).   The data requirements are listed in
the  order in  which they  appear  in 40 CFR Part  158.   The reference
numbers  accompanying  each  test  refer to  the  test  protocols set  out  in
the  Pesticide Assessment Guidelines,  which  are  available from the
National  Technical  Information  Service,   5285  Port  Royal  Road,
Springfield, VA   22161.

2.  Test Substance  (Column 2).   This column lists  the composition
of the test substance  required to be used for the  test,  as follows:

     TGAI = Technical  grade of the active ingredient
     PAI =  Pure active ingredient
     PAIRA = Pure  active ingredient, radio labeled
     TEP =  Typical end use formulation
     MP =   Manufacturing use product
     EP =   End use product

Any other  test substances,  such as  metabolites,  will be specifically
named in Column  2  or  in  footnotes  to the table.
                                       47

-------
 3.  Use pattern (Column 3).   This  column  indicates the use patterns to
 which the data requirement applies.  Use patterns are the same as
 those given in 40  CFR Part  158.  The following letter designations are
 used  for the given use patterns:

      A = Terrestrial,  food
      B = Terrestrial,  non-food
      C = Aquatic,  food
      D = Aquatic,  non-food
      E = Greenhouse,  food
      F = Greenhouse,  non-food
      G = Forestry
      H = Domestic  outdoor
      I = Indoor

 Any other designations will  be defined  in a footnote to the table.


 4.  Does EPA have  data? (Column 4).  This column indicates one
 of three answers:

      YES - EPA has data in  its files that completely satisfy
      this data requirement.   These data may be cited by
      other registrants in accordance with data compensation
      requirements  of  Part 152, Subpart  E.

      PARTIALLY - EPA  has some data in its files, but such data
      do not fully  satisfy the data requirement.  In  some cases,
      the Agency may possess  data on one of two required species,
      or may possess data on  one test substance but not all.
      The term may  also indicate that the  data available to
      EPA are incomplete.  In this  case, when the data are
      clarified, or additional details of  the testing submitted
      by the original  data submitter, the  data may be determined
      to be acceptable.   If  this is the  case, a footnote to
      the table will usually  say so.

      NO -  EPA either  possesses no  data  which are sufficient
      to fulfill the data requirement, or  the data which EPA
      does  possess  are  flawed scientifically in a manner that
      cannot be remedied by  clarification  or additional infor-
      mation.

 5.    Bibliographic citation  (Column  5).   If the Agency  has acceptable
data in  its files, this column lists the identifying number of each
study.   This  normally is  the  Master  Record Identification (MRID)
number,  but may be a GS number  if no MRID number has been assigned.
Refer  to the Bibliography Appendices for a complete citation of the
study.
                                   48

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6.   Must  additional data  be  submitted?  (Column 6).    This column
indicates whether the data  must be submitted to the Agency.  If column
3 indicates that the  Agency  already has data,  this  column will usually
indicate NO.  If column 3 indicates that the Agency has only partial
data or  no data,  this  column  will  usually indicate  YES.   In  some
cases, even though the Agency  does  not  have the  data,  EPA will not
require  its submission because of the unique characteristics of the
chemical; because data on another chemical can be  used  to  fulfill the
data requirement;  or  because the data  requirement  has been waived or
reserved.  Any  such unusual  situations will be explained in a  footnote
to  the  table.   N/A  indicates that  the data requirement  is not
applicable  to the use pattern.

7. Timeframe for submission  (Column 7).   If column 5  requires that
data be  submitted,  this column indicates when  the data are to be
submitted,  based on  the receipt date of the Registration Standard.
The timefraraes  are those established either as a result of a  previous
Data Call-in letter, or standardized timeframes established by PR
Notice 85-5  (August 22,  1985).

80  Footnotes (at the end of each table).  Self-explanatory.
                                49

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                                                         TABLE  A
                                              GENERIC  DATA  REQUIREMENTS FOR OXAMYL
    Data Requirement
  Test
Substance
                                                     Does  EPA      Bibliographic
                                                     Have  Data?!/  Citation I/
                                                                                           Must Additional   Timeframe
                                                                                           Data be             for
                                                                                           Submitted?       Submission?/
156.120 Product Chemistry

Product Identity and Composition

 61-2 - Description of Beginning         TGAI
          Materials and Manufacturing
          Process

 61-3 - Discussion of Formation of       TGAI
          Impurities

Analysis and Certification of
Product ingredient?

 62-1 - Preliminary Analysis             TGAI
                                                                                                  Yes
                                                                                                  Yes
                                                                                                  Yes
                                                                        6  Months
                                                                        6 Months
                                                                         12  Months
0 Physical and Chemical Characteristics

    63-2 - Color

    63-3 - Physical State

    63-4 - Odor

    63-5 - Melting Point
    TGAI

    TGAI

    TGAI

    TGAI
                                                                                               Yes

                                                                                               Yes

                                                                                               Yes

                                                                                               Yes3/
6 Months

6 Months

6 Months

6 Months

-------
                                                           TABLE  A
                                              GENERIC  DATA  REQUIREMENTS  FOR  OXAMYL
uatd Kequiremenc Test
Substance
1 SH 1 /Tl Prortnrt rhpmf^frv frnntinnpdl
1 ^O • 1 fc.V/ I • \7UUv> V Lilldli 1 j L I Jr I l_ Ull v 1 IIUCVJ |
Physical and Chemical Characteristics
[continued]
63-6 - Boiling Point
63-7 - Density, Bulk Density, or
Specific Gravity
63-8 - Solubility TGAI
63-9 - Vapor Pressure TGAI
63-10 - Dissociation Constant TGAI
63-11 - Octanol/Water Partition
Coefficient
63-12 - pH
63-13 - Stability
TGAI
TGAI
or PAI
or PAI
or PAI
PAI
TGAI
TGAI
Does EPA Bibliographic Must Additional
Have Data?!/ Citation I/ Data be
Submi tted?
Yes4/
Yes
Yes
Yes
Yes
Yes
Yes
Yes.
1 i me frame
for
Submissi on2/
6 Months
6 Months
6 Months
6 Month's
6 Months
6 Months
6 Months
6 Months
Other Requirements:

 64-1 -  Submittal of Samples
TGAI,  PAI
Reserved5/
 i;  ilthnuah oroduct chemistry  data  may  have  been  submitted  in  the past, the Agency has  determined thai   '         ~
     theledatS must be  resubmitted  for  each pesticide.   New  requirements have been introduced  and prev.ously  subm.tted
     these  aa" "";;;. trt    Therefore bibliographic  citations for the old data are not  applicable.
 21  D^'dates refer" to  the  number of 'months following  receipt of  this Registration Standard  by  the registrant, unless

 3,  £u^dei}ndtneatecdhnical  is a  solid at room temperature.
 li  S^u  rid  f the technical  is a  liquid at  room  temperature.
 \'/   HqslmP?es are needed,  the  Agency will  request them.

-------
                                                                   TABLE  A
                                                      GENERIC DATA REQUIREMENTS  FOR  OXAMYL
 "•*
c_n
Data Requirement
158.130 Environmental Fate
DEGRADATION STUDIES-LAB:
161-1 - Hydrolysis
Photodegradation
161-2 - In Water
161-3 - On Soil
161-4 - In Air
METABOLISM STUDIES-LAB:
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
ifi?_4 - Aerobic Aauatic
Test
Substance
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
PAIRA
Use
Pattern
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
ABEF
Does EPA
Have Data?
Partially
Partially
No
No
Yes
No
No
NO .
Bibliographic Must Additional Timeframe
Citation Data be for
Submitted? Subnhssionl
00040494 Yes 9 Months
00040494 Yes 9 Months
7
N/A
8
N/A
00063012 No
2
Yes 27 Months
7
N/A
7
N/A
MOBILITY STUDIES:

 163-1 - Leaching and
         Adsorpti on/Desorpti on
                                             PAIRA
ABEF   Partially
00040494
00141395
00154748
                                                                                                   Yes
                                                                                                                   12 Months

-------
                                             TABLE A
                                GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158.130 Environmental Fatekonti
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
DISSIPATION STUDIES-FIELD:
164-1 - Soil
164-2 - Aquatic (Sediment)
164-3 - Forestry
.3 164-4 - Combination and
Tank Mixes
164-5 - Soil , Lc..g-term
en
^ ACCUMULATION STUDIES:
165-1 - Rotational Crops
(confined)
165-2 - Rotational Crops
(field)
165-3 - Irrigated Crops
165-4 - In F1sh
.rr r T- A/iujtir WnntArQPt
lest Use
Substance Pattern
nued)
TEP ABEF
TEP ABEF
TEP ABEF
TEP
TEP
TEP
TEP ABEF
PAIRA ABEF
TEP ABEF
TEP
PAIRA ABEF
TEP
Does EPA
Have Data?
No
No
Yes
No
No
No
No
No
No
No
No
No
Bibliographic Must Additional Timeframe
Citation Data be for
Submitted? Submissionl
N/A8
N/A8
1492J1 Yes 27 Months/2
7
N/A
N/A7
N/A7
4
Reserved
Yes 39 Months/2
ReservedS
7
N/A
6
N/A
7
N/A
Organi sms

-------
                                                         TABLE A
                                             GENERIC  REQUIREMENTS FOR OXAMYL
158.130 Environmental Fate   -  Footnotes
 I/  Due dates refer  to  the  number  of  months  following  receipt  of  this Registration Standard by  the  registrant, unless
     otherwise indicated.

 2/  First progress report due  8  months  after receipt of  this Standard.  Interim reports are due semi-annual ly
     thereafter.

 3/  Data are required on aged  residues  using a  column  leaching study  indicating adequate identification of residues.

 4/  Pending evaluation  of information in  soil  studies  164-1.

 5/  Pending results  of  confined  rotational crop study.

 6/  Octanol-watei partition coefficient is 0.33.

 II  Not required because the registered use  patterns preclude  the  necessity for these studies.

 8/  Not required because the appropriate  protective equipment  triggered by the study results already appears on
     registered labels.

-------
                                                        TABLE A
                                          GENERIC DATA REQUIREMENTS FOR OXAMYL
Data
158.
132-1
132-2
132-3
132-4
158.

158.
201-1
201-1
Requirement
140 Reentry Protection
- Fol iar Dissipation
- Soil Dissipation
- Dermal Exposure
- Inhalation Exposure
75 Other Exposure Data
- Glove Permeabil i ty
142 Spray Drift
- Droplet Size Spectrum
- Drift Field Evaluation
Test
Substance

TEP2
TEP
TEP
TEP

TEP2

TEP2
TEP2
Use
Pattern

ABEF
A
ABEF
ABEF

ABEF

AB
AB
Does EPA Have.
Data?

Partial
No
Partial
Partial

No

No
No
Bibliographic Must Addi tional
Citation Data be Submitted?

163605 Yes3
Yes
163606 Yes3
163606 Yes3

Yes4

Yes6
Yes6
Time frame
for

21 Months
21 Months
27 Months
2? Months

9 Months5

12 Months
12 Months
I/  Due dates  refer to the number of months following receipt of  this  Registration Standard by the  registrant, unless
    otherwise  indicated.
2/  SC formulation only.
3/  Additional  information is needed to complete estimation of reentry  intervals.  This information  is needed for
    conversion  of  the reported data to surface residue levels.
4/  Study  using several  materials and conducted according to methods in  "Standard Test Method fo  Resistance of
    Protective  C~c*hing  to Permeation by Hazardous Liquid Chemicals",  ASTM.
5/  Protocol required within 3 months of receipt of this  Standard.
6/  The  droplet size spectrum and the drift field evaluation data may be done together in order  to evaluate the  drop
    spectra  associated with actual field use patterns.

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                                                        TABLE A
                                          GENERIC DATA REQUIREMENTS FOR  OXAMYL
Data Requirement
158.135 Toxicology
ACUTE TESTING:
81-1 - Acute Oral Toxicity - Rat
81-2 - Acute Dermal Toxicity -
Rabbit
81-3 - Acute Inhalation Toxicity
Rat
01
ON 81-7 - Acute Delayed
Neurotoxici ty- Hen
Test Use Does EPA
Substance Patterns Have Data?


TGAI ABEF Yes
TGAI ABEF Mo
- TGAI ABEF Yes
TGAI ABEF No
Bibliographic Must Additional
Citation Data be
Submitted?


063011 No
Yes
066902 No
066903
2
NA
Time frame
for
Submissi onl


9 Months
I/  Due dates refer to  the  number  of  months following receipt of  this  Registration  Standard  by  the registrant,  unless
    otherwise Indicated.

21  This study is not required  since  the  subject compound is  not  an  organophosphate.

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                                                        TABLE A
                                          GENERIC DATA. REQUIREMENTS FOR OXAMYL
Data Requirement
158.135 Toxicology (continued)
SUBCHRONIC TESTING:
82-1 - 90-Day Feeding: Rodent
and Nonrodent (Dog)
82-2 - 21-Day Dermal - Rabbit

82-3 - 90-Day Dermal - Rabbit

82-4 - 90-Day Inhalation - Rat

82-5 - 90-Day Neurotoxici ty
Test
Substance



TGAI
TGAI

TGAI

TGAI

TGAI
Use
Patterns



ABEF
ABEF

ABEF

ABEF

ABEF
Does EPA
Have Data?



No
No

No

No

No
Bibliographic Must Additional
Citation Data be
Submitted?



No?
Yes
3
NA
3
NA
4
NA
Time frame
for
Submi ssi on!




7 Months






I/  Due dates  refer  to the number of months following receipt of this Registration  Standard by the registrant, unless
    otherwise  indicated.
21  Not required  under the present circumstances since chronic studies in  the  rat,  dog and mouse are  needed.  The
    registrant should be  aware that subchronic studies are necessary to establish the MTD in rodent oncogenicity
    studies.
3/  Requirement not  applicable because of lack of serious exposure with registered  use patterns.
4/  This  study is not required since the compound is not an organophosphate.

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                                                              TABLE A
                                                GENERIC DATA REQUIREMENTS FOR OXAMYL
Data
158.1
Requi rement
35 Toxicology (continued)
Test
Substance

Use Does EPA
Patterns Have Data?

Bibliographic Must Addi ti ondl Timeframe
Citation Data be for
Submitted? Submission/1

CHRONIC TESTING:
83-1
83-2

83-3
83-4
- Chronic Toxicity -
Rodent and Non-Rodent
- Oncogenicity -
Mouse
Rat
- Teratogenici ty -
Rat
Rabbit
- Reproduction - Rat
2-generation
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
ABEF No
ABEF Yes
ABEF No
ABEF No
ABEF Yes
ABEF No
Yes2 42 Months3
076813 No
Yes 42 Months3
Yes 12 Months
063009 No
3
V 20 Months
CO
I/  Due dates  refer  to  the  number  of  months following receipt of this  Registration  Standard by the registrant, unless
    otherwise  indicated.
2/  Both Rodent and  NonRodent Required.
3/  First progress report due 8 months  after receipt of this  Standard.   Interim reports  are due semi-annually
    thereafter.

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                                                         TABLE  A
                                           GENERIC DATA REQUIREMENTS  FOR  OXAMYL
Data Requirement
158.135 Toxicology (continued)
MUTAGENICITY TESTING:
84-2 - Gene Mutation
84-3 - Structural Chromosomal
Test
Substance
TGAI
TGA1
Use
Patterns
ABEF
ABEF
Does EPA Bibliographic
Have Data? Citation
No
No
Must Addi
Data be
Submitted?
Yes
Yes
tional Timeframe
for
Submissionl/
10 Months
10 Months
        Aberration

84-4 - Other  Genotoxic Effects
       (ONA Damage)

SPECIAL  TESTING

85-1  - General Metabolism
   TGAI           ABEF
PA1 or PAIRA     ABEF
Yes
00040594
                                                         No
                                                         Yes
                                         14 Months
  I/  Due dates  refer  to the number of  months following  receipt  of  this Registration  Standard by the registrant, unless

      otherwise  Indicated.
  21  First progress  report due 8 months after receipt of  this Standard.  Interim reports  are due semi-annual ly

      thereafter.

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                                                     TABLE A
                                       GENERIC DATA REQUIREMENTS  FOR  OXAMYL
Data
Requl rement
Test
Substance
Use Does EPA Bibliographic Must Additional Timeframe
Patterns Have Data? Citation Data be for
Submitted? Submissionl/
58.145 Wildlife and Aquatic Organisms
AVIAN AND MAMMALIAN TESTING:
71-1
71-2
71-3
71-4

71-5
- Acute Avian Oral Toxlclty
- Avian Subacute Dietary
- Upland Game Bird
- Waterfowl
- Wild Mammal Toxlcity
- Avian Reproduction
-Upland Game Bird
-Waterfowl
- Simulated and Actual
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TEP3
AB
AB
AB
AB
AB
AB
AB
Yes
No
No
No
Yes
Yes
No
0094660 No
Yes
Yes
2
Reserved
0116610 - No
0116609 No
Yes4

9 Months
9 Months


48 MonthsS
     Actual Field Testing -
     Mammals and Birds
o\

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              TABLE A
GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement Test Use Does EPA Bibliographic Must Additional Time frame
Substance Patterns Have Data? Citation Data be for
Submitted? Submissionl/
S8.145 Wildlife and Aquatic Organisms (continued)
-QUATIC ORGANISM TESTING
72-1
72-2
72-3
ON
72-4
- Freshwater Fish Toxicity
- Coldwater Species
- Warmwater Species
- Acute Toxicity to
Freshwater Invertebrates
- Acute Toxicity to Estuarine
and Marine Organisms
- Fish
- Shrimp
- Oyster
- Fish Early Life Stage,
and Aquatic Invertebrate
Life Cycle
- Fish
t — .,^«»*-aK»*atP
TGAI AB Yes 0066914 No
TGAI AB Yes 0066916 No
TGAI AB Yes 0094664 No
TGAI AB No Ves6
TGAI AB Yes 0113412 , No
TGAI AB Yes 0113414 No?
TGAI AB NO Ves8 15 Months9
TGAI AB Yes 0094664 No

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                                                       TABLE A

                                          GENERIC DATA REQUIREMENTS FOR OXAMYL
  Data Requirement                     Test         Use      Does EPA    Bibliographic   Must  Additional  Timeframe
                                    Substance    Patterns   Have Data?  Citation        Data  be           for
	Submi tted?	Submissionl/


 156.145 Wildlife and Aquatic Organisms(continued)


 AQUATIC ORGANISM TESTING


  72-5 - Fish  - Life Cycle            TEP        AB          No                         N/A
                                                                                         10

  72-6 - Aquatic Organism             TEP        AB          No                         N/A
        Accumulation
                                                                                              11

  72-7 - Simulated or Actual Field    TEP        AB          No                         Reserved

        Testing

  I/ Due  dates refer to the number of months  following receipt of  this Registration  Standard  by  the registrant, unless

     otherwise indicated.                                                              .           ,
  2/ Reserved pending  the results of field  field studies and the necessity of  dietary studies on mammals to  assess

     risks  or interpret field studies.

  \Jl A°th;»lthfield tesUnYwith birds$andemammaU'is required to  support all uses  of  the 10 G formulation and all foliar
     annlicatlons of 24%SC products.  For the  granular product,  a  field study  using  band applications on  peanuts is
      sSec flcalW Squired to support that  uselunincorporated application). An additional field  study with the granular
       oreflrab y on Jomatoes) is required to  support  the other granular uses.   Study design should  include appropriate
      (preferably on ™""/ •    «J       h1n r\Q determine pesticide-induced mortality and extent.  For the  24% SC,

      He  °d  stud e     re  requ ^do^eseuent of use Snd wildlife  utilization),  on  potatoes       induced wrt>my and the potent.at effec s „,, ,an breed  g «" »^^^^"^gistrants are  encouraged  to

     coniuuVth thfS c5' o  erntn  11^^1111 studies prior to the  initiation of  field studies.

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                                                         TABLE  A
                                           GENERIC DATA REQUIREMENTS FOR  OXAMYL
158.145 Mildllt^ and  Aquatic  Organisms (continued)


 5/  Protocols must be  submitted within 12 months.   These protocols must include  specific sites and a detailed  outline
     methodology and  experimental  design.   Registrants are strongly encouraged  to  submit preliminary protocols within
     6 months.
 6/  96 hour LC50  required based on the potential for runoff into estuarine areas  from crop uses.
 7/  Tests on  the  24% SC  satisfy requirements for the technical.
 8/  Required  for  uses  where  estimated environmental concentrations exceed .01  the Fish LC50.  These include  all foliar
     applications   greater  than  1.0  15  ai/A,  soil applications of the 24X SC  that  are  not  incorporated,  soil
     applications   of  the 10 G at 2.0 Ib.  ai/A or greater, and applications by in-furrow irrigation water that do not
     specify   methods (e.g. retention) to prevent the runoff of treated water.
 9/  First progress  report due 8 months after receipt of this Standard.  Interim reports are due semi-annually
     thereafter.
107  Study not required because the octanol/water partition coefficient is O.JJ
III  Maximum estimated environmental concentrations in aquatic habitats exceed  1/2 the LC50 for the most sensitive
     aquatic  Invertebrate from foliar applications at 2.0 Ib ai/A and above, from  granular soil treatments  for peanuts
     a-nd  ornamentals   and from liquid soil treatments for eggplant, peppermint, spearmint, and garlic (SLNs from
     CA 4 OR?    Aquatic residue monitoring studies are reserved, pending an evaluation of required environmental fate
     studies    Ac?ual field studies for aquatic  invertebrates are reserved for  the same uses and will be required if
     ?} aquatic residue monitoring demonstrates  that residues exceed 1/2 the LC50  for the most sensitive aquatice
     Invertebrates.

-------
                                            GENERIC  DATA  REQUIREMENTS FOR OXAMYL
Data Requirement
158.155
Nontarget
NONTARGET INSECT
141-1 -
141-2 -'
141-4 -
141-5 -
Honeybee
LD50
Honeybee
residues
Honeybee
feeding s
Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data? Citation Data be for
Submitted? Submission I/
Insects
TESTING - POLLINATORS:
Acute Contact TGAI AB Yes 00036935 No
05001991
2 3 4
- toxicity of TEP AB No Yes 15 Months
on foliage
subacute TEP AB No ReservedS
tudy
Field testing for TEP AB No N/A
pol 1 i nators
I/ Due dates refer to the number  of  months  following receipt  of  this Registration Standard by the registrant,
   unless otherwise indicated.
21 SC formulation
3/ As data from the acute toxicity study  indicate  a  high  toxicity,  residual toxicity data are required.
4/ First progress report due 8 months  after receipt  of  this Standard.   Interim reports are due semi-annual ly
   thereafter.
5/ Reserved pending development of test methodology.

-------
                                                           TARI.E  A

                                             GENERIC DATA REQUIREMENTS  FDR OXAMYI,
  Data  Requirement
     Test
   Substance
                                                  Does EPA
                                                  Have Data?
   $158.125 Residue Chemistry

   171-2  -.Chemical Identity^/

   171-3  - Directions  for  Use  (See Index)

   171-4  - Nature of Residue
             (metabolism)

           Plants
           Livestock
G\
171-4 - Residue  Analytical
          Methods

        Plants and animal
          residues
   171-4  -  Storage Stability  Data
                                                      Yes
                                         PAIRA
                Partially
     TGAI         Yes
and metabolites
     TEP
     or PAI
                                                    Partially
Hibl lograph i c
  Citation
                                00028728,
                                00039S11,
                                00040496,
                                00040597,
                                00040605,
                                00003525,
                                00134709

                                00028732
                                                                    00081610,
                                                                    00113341 ,
                                                                    00113357

                                                                    00081618
 Must Ad.) i t i ondl
Data Be Submi t. te.1?
                                                                                         No
                                                     Reserved6/
                                                     Yes7,8/
T i iitf I i Mine tor
  Submission1/
                                                                                                        18 Months5'/
                                                                                                       18 Months^/

-------
                                                        TABLE A

                                          GENERIC DATA REQUIREMENTS  FDR OXAMYI.
Data Requirement
  Test       Does EPA      Bibliographic    Must. Additional
Substance    Have Data?      Citation      Data Re Submi11tv
$158.125 Residue  Chemistry (cont'd)

171-4 - Magnitude of the Residue - Crop  field  trials
ON
- Root and tuber
    vege '

  o Carrots

  o Ginger

  o Potatoes
                                      TEP        Partially

                                      TEP          No

                                      TEP, EP    Partially
  o Sweet potato

- Bulb Vegetables Group14/

  o Garlic

  o Onion

- Leafy Vegetables Group16/

  o Celery                    TEP
               Yes



               No

               No



             Partially
                                                         00113339
                                                         00040607,
                                                         00113339,
                                                         00113370

                                                         00113339
                                                                  0037130,
                                                                  0061648,
                                                                  0113410,
                                                                  0147614
                                                 Yes10/
                                                                             Yes11/
                                                 Yes'V3/
                                                                                     No
                                                                                     No
                                                                                           Time frame  for
                                                                                              Subrai ssion1/
18 Months^/

1B MonthsV

18 Months5,43/
                                                                                                    18 Months
                                                                                                    18 Months5/

-------
                                                         TABU: A

                                           GENERIC DATA HEQUIREMENTS FDR OXAMYL
 Data Requirement
  Test
Substance
                                                 Does EPA
                                                 Have Data?
Bibliographic
  Citation
$158.125 Residue Chemistry  (confd)

171-4 - Magnitude  of the Residue (cont'd)

        - Crop  field trials

        - Legume Vegetables Group20/

          o Soybeans                 EP

        - Foliage  of the Legume
            Vegetable Group22/

          o Soybean straw

        - Fruiting Vegetables Group	/
ON
            o Eggplant
            o Peppers
            o Tomatoes
                                      25.
          - Cucurbit Vegetables  Group__/
            o Cantaloupe
            o Cucumbers
   EP
   EP
                                                  Partially
                                                    Yes
               Yes
               Yes
                                       TEP, EP     Partially
                                                    Yes
                                                    Yes
                                                                  00030920
                                                                  00030920
                                                                 00081618
                                                                 00081618,
                                                                 00113387,
                                                                 00138996,
                                                                 00145315

                                                                 00040603,
                                                                 00048060,
                                                                 00084889,
                                                                 00113419
  00143312
  00143312
 Must Addi 11onal
Data Be Submi tte
-------
              TABU: A
GENERIC DATA HEQU I RE MK NTS  FOR OXAMYi.
Data
$158
171-
o\
CO
Test Does EPA
Requirement Substance Have Data?
.125 Residue Chemistry (cont'd)
4 - Magnitude of the Residue (cont'd)
- Crop field trials
- Cucurbit Vegetables Group^/
( cont'd )
o Honeydew melon Yes
o Pumpkins EP No
o Summer squash Partially
o Watermelon Yes .
o Winter squash Yes
- Citrus Fruits Group EP, TEP Partially
- Pome Fruits Group30/
o Applts EP Yes
o Pears Partially
- Miscellaneous Commodities
o Bananas EP Partially
11 i hi icxjraphi c Must Additional T i m.j trame for
Citation Data Be Submitted? Submission1/
00143312 No
Yes2f>/ 6 Months
00143312 No£^7
00143312 No
00143312 No
00113343 Yes29,29/ 18 Months^,43/
00067234, No
001 1 3373
00063016 No31/
00113309, Yes_^/ 6 Months
00129354,
001421 26

-------
                TABLE  A






GENERIC DATA REQUIREMENTS  FOR OX AMY I,
Data
$158
171-

Requirement
.125 Residue Chemistry (conf
4 - Magnitude of the Residue
- Crop field trials
Test Does EPA
Substance Have Data?
d)
(cont'd)

Bibliographic Must Additional Timeframe for
Citation Data Be Submitted? Submission1/



- Miscellaneous Commodities (cont'd)







r\
O
o Cottonseed
o Mint
o Peanuts

o Pineapples
o Tobacco
- Nonbearing Fruits
- Meat/Milk/Poultry/Eggs


TEP, EP Partially
EP Yes
TEP Partially

TEP, EP Partially
TEP No
TEP No
Partially


00113341 Yes33,34/ 24 Months5,43/
00126690 No
00083522, Yes3S,36/ 24 Months^, _4_3/
00113357
00113380 Yes37,38/ IB Months5,43/
YesT75,^/ IB Months^, ^/
yes41/ 24 Months5/
00039513, Reserved^/
00040592,
00083524,
001 1 3376

-------
                                                           TABLE A

                                             GENERIC DATA REQUIREMENTS FOR OXAMYI,
   Footnotes:
   §158.125 Residue  Chemistry

   _»_/  Data must be  submitted within the indicated timeframe, based on the date of this Guidance Oocunu.nl.

   2/  Refer to Product  Chemistry Data Requirement tables.

   2/  Studies of  the  metabolism of (14C)oxamyl in ruminants and poultry.  Animals must be dosed for at  least  3 days at
       a level sufficient  to make residue identification and quantification possible.  Milk and eggs must he collected
       twice daily during  the dosing period, and animals must be sacrificed within 24 hours of the final dose.  The
       distribution  and  identity of residues must be determined in milk,  liver, kidney, muscle, and fat  of  ruminants,
       and in eggs,  liver,  kidney,  muscle,  and fat of poultry.

   _4/  Samples from  studies  requested  in footnote 3 must be analyzed using current enforcement methods to determine  the
       usefulness of these  methods  for analysis of animal commodities.

   5/  First Progress  Report due 8  months after receipt of this Standard.  Interim Reports are due semiannually
       therea fter.

   6/  If the animal metabolism  data required in the section entitled, "Nature of the Residue in Animals" reveal
       additional metabolites of toxicological concern or the Toxicology Branch determines that any plant metabolites
       must be included  in  the tolerance definition,  additional analytical methods and validation data may  be  required.

~^J 7/  The storage intervals and conditions  of samples used to support all established tolerances for  residues must be
O~   submitted.  These data must  be  accompanied by data, depicting the percent decline in residues at the  times and
       under the conditions  specified.   (No  additional stability studies  are required for plant commodities stored
       frozen for up to  12 months.)  On receipt of 'these data, the adequacy of the aforementioned tolerances will be
       reevaluated.

   8/  All  residue data  requested  in this Standard must be accompanied by data depicting the duration  and conditions
       of storage of samples analyzed.   These data must be accompanied by data depicting the stability of residues
       under  the conditions  and  for  the time intervals specified,  with the exception  of plant commodities stored
       frozen for up to  1 2 months.   For laboratory tests using fortified  samples,  the pure active ingredient must b«>
       used   If field-weathered samples are used, the test substance must be a Ti-P.

-------
                                                          TABI.E A

                                            GENERIC DATA REQUIREMENTS FOR OXAMYL
 Footnotes:
 $158.125 Residue Chemistry  (cont'd)

 2/  If the  registrant wishes  to  propose  a  crop group tolerance,  use directions must be proposed  and  residue data
     submitted for the additional  representative crops radish and sugar beet,  in addition to the  data  r,quired to
     support established tolerances  for  residues in or on carrot and potato.

 _HV Data depicting residues of oxarayl  in or on carrots following the maximum  seasonal  treatment  regime:  the 2 Ib/gal
     SC/L or 10\ G formulation preplant  incorporated at 8 Ib/ai/A and at-plant in-furrow at 4  Ib/ai/A  followed by
     three  foliar applications of  the  2  Ib/gal  SC/L made at 2-week intervals at 1  Ib/ai/A.   Samples must be collected
     at the  14-day PHI.  Tests must  be  conducted in MI.  Alternatively, the registrant  may  elect  to cancel this use
     permitted under EPA SLN No.  MI-820022.

 11/ Data depicting residues of oxamyl  in or on ginger following separate full-season treatment regimes with the
     2  Ib/gal SC/L formulation:   (i) a  4  Ib/ai/A preplant incorporated (I'PI) soil  treatment followed by two foliar
     treatments, the  first at  4 weeks  postplanting and the second 3 weeks later;  and (ii) soil  applications at
     4  Ib/ai/A by drip irrigation  emitters  at 1 week postplantinq and repeated at  14-day intervals until 30 days
     prior  to harvest.  Tests  must be  conducted in HI.  The registrant must specify a maximum  seasonal rate or
     number  of appl ica-t i ons  for the  drip  irrigation use which must be reflected in the  submitted  data.

 12/ Data depicting residues of oxamyl  in or on potatoes following a full-season  treatment  tegime, including multiple
     foliar  applications and soil  applications  (in-furrow and preplant, in separate tests).  The  2 Ib/qal  SC/L  or
     10\ G  formulation must  be applied  in-furrow at 4 Ib/ai/A and, in separate tests, band/broadcast preplant
 '   incorporated at 8 Ib/ai/A within  1 week of planting.   The SC/L must be applied in  a volume of at least
     20 gal/A.  Foliar applications  of  the  2 Ib/gal SC/L must be made at 1  Ib/ai/A and  repeated at S-day intervals.
     Samples must be collected 7  days  after  the final application.  The registrant must specify a maximum seasonal
     rate or number of applications  for  foliar  treatments  which must be reflected  in the submitted data.  Tests
^    must be conducted in 10(24%),  WI(6\).  ND(5.7\), O>{5\),  and  ME(6%) which  collectively  represented ca.  77%
     of 1984 U.S. potato production  if  ID represents OR(6%)  and  WA(16%) and  WI  represents Ml (4%) and HN(4.5%)
     (Agricultural Statistics, 1985, p.  164).

 'I/ Data depicting residues in wet  and  in dried potato peels,  potato granules, and chips from potatoes bearing
     measurable weathered residues of  oxamyl.  Should residues concentrate in  any  of these  commodities, appropriate
     food or feed additive tolerances must  be proposed.

-------
                                                           TABU: A

                                             GENERIC DATA REQUIREMENTS FOR OXAMYL
   Footnotes:
   §158.125 Residue Chemistry (cont'd)

   14/ If the registrant  wishes  to propose a crop group tolerance, data depicting residues of oxamyl  in  or on
       the representative group member  onion to support the established tolerance must be submitted along with
       data depicting oxamyl  residues in or on garlic following maximum seasonal use regimes with the 2  Ib/gal SC/L
       formulation-.   (i)  four applications in CA tests at 2 Ib/ai/A, one at-planting in-furrow and three postemergent
       treatments via  irrigation water  (sprinkler or ditch) or as 1- to 2-inch band treatments to the soil surface
       at the base of  the plant;  and (ii) an in-furrow band or drench application at 4 Ib/ai/A followed  by three
       postemergent bands (6- to 8-inch) or broadcast treatments at the same rate in OR (OR-810033).   In OR,  samples
       must be collected  at  the 14-day  PHI.  For CA, the registrant must propose a PHI which must be  supported by
       the data  (EPA SLN  No.  CA-820068).

   IS/ No data are required  for  garlic  because data required  for onions (see footnotes 16 and 17) will be translated
   —  to garlic.  It  should  be noted,  however, that translated data may not be used to support a crop group  tolerance.

   16/ Data depicting oxamyl  residues in or on onions following:  (i)  four applications in CA tests at 2 Ib/ai/A, one
   ~~  at-Dlantinq in-furrow  and three postemergent treatments via  irrigation water (sprinkler or ditch) or as 1- to
       2-inch band treatments"^ the soil surface at the base of  the plant (CA-U2006B); and  (ii) an in-furrow band or
       drench application at  4 Ib/ai/A  followed by three postemergent band (6-8 inch) or broadcast treatments made
       at 14-dav  intervals at the same rate in OR (OR-810033).  In OR, samples must be collected at. the 14-day Pill.
-J     For CA  the registrant must propose a PHI which must be supported by the data (EPA SLN No. CA-82000U,   If the
       For LA, tn    y            support the OR-810033 or CA-820068 label, the MI-840005 label must be supported  (one
       registrant chooses not to support the  «         ^emergent applications at 0.25 ib/ai/A at M-day intervals
       in-furrow application  at 2 Ib/ai/A pi        F   PU                support the MI-840005  label, the  ID-830019,
       0^^%^^                                         (multipirpostemerqent applications at  0.25  Ib/ai/A
       OR-830025TX 8^0046   and                  ^^ ^  ^^ con(jucted  in IQ and Tx).  Tne rt,Jlstrant must

       ."eel* a* -XV6:::  seasonal r.teVnu-b-r of postemergent  applications which must be  reflected by the  data.

                          . ,-nond the 24(0 labeling for EPA SLN No. NM-810021 to specify an  upper limit for treatment
   U/ The registrant  must *«£ ^.  4(c) 1      *               CA-820068 or OR-810033 or  the  upper limit ,s <  0.25
       and submit supporting data <"nle^  ™   J      OR-810033  and CA-820068  to include restrictions on harvesting
       Ib/ai/A -  See(^ttaer9na/tiavberye)i tolerance must be proposed  and appropriate supporting  residue data submitted
                           n          in  or on green onions ,6Sulting from these us,,.,

-------
                                                         TABLE A

                                           GENERIC DATA REQUIREMENTS FJR OXAMYL
Footnotes:

§158.125  Residue Chemistry  (confd)

_HV  If  the  registrant wishes  to  propose a crop group tolerance, use directions must be proposed, and appropriate
     supporting residue data  submitted for additional representative group members 'lettuce and spinach.   Also,
     additional required data  to  support the established tolerance for residues of oxamyl in or on the representative
     crop  group member celery  must be submitted.

1 9/  Data  reflect -j residues  in  or on untrimmed celery 14 days after the last of several foliar applications ,11
     5-day intervals of the  2  Ib/gal  SC/L formulation at 1 Ib/ai/A.  Tests must be conducted in I'l. to support S I.N
     No. FL-760019, the registered use most likely to result in the highest residues on celery.  The fill's  for
     trimmed celery must be  deleted from the label since Agency policy is to set tolerances on and require data
     for untrimmed celery.   Also,  the registrant must specify a maximum number of applications/crop or a  maximum
     seasonal use rate which must be supported by the data requested above.  If the registrant of the t'L-760019
     label chooses not to  support the FL use, registered uses in MI (MI-820014 and MI-770010)  must be supported
     with  data reflecting  residues resulting from a single preplant broadcast application of the 10% G  formulation
     at  6  Ib/ai/A.  The granules  should be soil-incorporated to a depth of 4 to 6 inches.  Following this preplant
     application, three foliar applications of the 2 Ib/gal SC/L formulation at 1 1 b/ai/A/appl i ca t ion must be made
     at  2-week intervals  to  transplanted stock.  Samples of untrimmed celery should be harvested 14 days  after the
     final application.  Tests must be conducted in MI.  If the registrant does not wish to support the use permitted
     under EPA SLN No. MI-820014  but does wish to support use under MI-770010 or PA-800039,  the above data are
     required  from either  PA or MI with the exception that the preplant application must be made at 4 Ib/ai/A with
     the 2 Ib/gal SC/L  formulation.

 20/  I f  the registrant wishes  to  propose a crop group tolerance, use directions must be proposed and appropriate
—  supporting residue data submitted for the representative group members succulent and dry  beans and succulent
     and dry peas.

 21 /  Data  depicting residues in grain dust, meal, hulls, soapstock, and crude and refined o,ls  processed  from soybeans
~  bearing measurable,  weathered residues.  Should residues concentrate in any of these processed commodities,
     appropriate  food/feed additive tolerances must be proposed.  It may be necessary to apply  exaggerated rates
     to  obtain measurable  residues in the raw agricultural commodities.

-------
                                                         TABU-; A

                                           GENERIC DATA REQUIREMENTS FOR OXAMVI,
 Footnotes:
 J158.125 Residue Chemistry  (cont'd)

 22_/ If the registrant  wishes  to propose a crop group tolerance,  use directions  must  be  proposed and supporting
     residue data _,  bmitted  for  the representative group members  bean and  pea  vines and  hay.

 23/ At present, the registered  uses  on members of this group are sufficiently different that  establishment of a
     crop group  tolerance  is  inappropriate.

 24/ Data depicting  residues  in  wet and dry pomace,  catsup,  and juice processed  from  tomatoes  bearing measurable
     weathered residues.   If  residues concentrate in any of  these processed  commodities,  then  appropriate food/feed
     additive tolerances must  be proposed.

 25/ If the registrant  wishes  to propose a crop group tolerance,  data depicting  oxamyl residues in or on summer
     squash harvested 1 day after  the last of the following  treatments:  application  of  the 2  Ib/gal SC/L or 10%  G
     formulation at  4 Ib/ai/A  as a  preplant incorporated broadcast treatment and multiple foliar applications at
..    7-day intervals of the 2  Ib/gal  SC/formulation  at 1 Ib/ai/A.  Tests must  be conducted  in  CA(15%), PL(21%),
     GA(7%), NJ(6\), and TX(7%)  which collectively account for 56\ of U.S.  acreage  in squash and represent the
     major geographic regions  of squash production (1982 Census of Agriculture,  Vol.  1,  Part 51, p. 353).  Tests
»    in CA must  include, separately,  aerial and ground applications.

 26/ There are no registered uses  of  oxamyl on pumpkins.  A  registrant must  propose a use or the tolerance will be
     revoked,  th'e proposed use  on pumpkins must be  identical to  the registered  use on winter  squash as the winter
     squash data are used  to support  the tolerance (2 ppm)  for pumpkins.  Otherwise,  the proposed use on pumpkins
     must be accompanied by appropriate residue data to assess the adequacy  of the  established  tolerance.

 27/ Although insufficient data  are available for summer squash,  no additional data are  required because the available
 —  data for cucumber  may be  translated to support'the established tolerance  for residues  in/on summer squash.  However
     it should be noted that  translated data may not be used to support a  crop group  tolerance.

 ?H/ Data depicting  oxamyl residues in or  on sweet oranges,  lemons,  and grapefruits harvested  7 days after the last  of
 -  three foH« treatments at  4  Ib/ai/A.  Tests must be conducted in TX  to support  EPA SLN No. TX-800037.   Alterna-
     tely, the registrant may  elect to cancel EPA  SLN No.  TX-800037.

-------
                                                           TABLE A

                                             GENERIC DATA REQUIREMENTS  FOR OXAMYL
   Footnotes:

   $158.125 Residue Chemistry (cont'd)

   29/ Data depicting  oxamyl  residues in molasses and oil processed  from citrus fruits bearing measurable,  weathered
       residues.  Should  residues concentrate in any processed product, an appropriate food/feed additive  tolerance
       muat.be proposed.

   30/ If tne registrant  wishes to propose a crop group tolerance, data depicting residues of oxamyl  in or  on pears
       harvested  14 days  following multiple foliar applications of the 2 Ib/gal SC/L formulation at 2 Ib/ai/A/
       application  in  100 to  600 gal/A using ground equipment.  The registrant must propose a maximum seasonal
       rate  or number  of  applications.  The required data must reflect this proposal.  Tests must be  conducted
       in WA(29%),  NY(3l),  and CA(43\);  these States produced approximately 75\ of the total 1984 U.S.  pear crop
       (Agricultural S tatistics, 1985, p. 214).  (Although there  is presently no registered use in CA,  for  a crop
       group tolerance data would be needed from all geographic production regions.) •

   31/ Although  insufficient  data are available for pears, the available apple data may be translated to support
       the established tolerance for residues in/on pears.  It should be noted, however,  that translated data may
       not be used  to  support a crop group tolerance.

~-^12/ All labels permitting  use of oxamyl on bananas grown in countries that export bananas to the United States must
(j"l     be submitted and accompanied by English translations.  On  receipt of these labels, the adequacy  of  the
       established  <_3i trance  will be reevaluated.

   33/ Data  from aerial application tests using the 2 Ib/gal SC/L formulation depicting residues of oxamyl  in or
   —  on cottonseed harvested (i) 21 days after the last of four treatments of 1  Ib/ai/A applied in  3  gal water/A
       (tests conducted in AZ and CA) ; and (ii) 14 days after the last application of several  at 0.25 Ib/ai/A
       applied,  in  separate tests, in 2 gal water/A and 0.375 gal refined vegetable oil/A (tests conducted  inTX).
       The registrant  must amend EPA SLN Nos. TX-840010 and TX-820005 to specify a maximum seasonal rate or number
       of applications which  must be reflected in the data submitted.

   14/ Data  from a  processing study depicting oxamyl residues in hulls, soapstock,  crude  oil,  and refined oil
       nrocessed from  cottonseed bearing measurable, weathered residues.  Processing procedures,  including heating
       temperatures and times, must be clearly representative of those in current  use for commercial  processing.

-------
                                                           TABU-: A

                                             GENERIC DATA REQUIREMENTS FOR OXAMYI,
   Footnotes:
   §158.125 Residue Chemistry (cont*d)

   2V Data depicting  residues in or  on peanut vines and hay harvested after a foliar application of  the  2 Ib/gal SC/L
       formulation  at  1  Ib/ai/A made  6 weeks after emergence and preceded by a foliar application 3 weeks earlier at
       the same  rate,  and  an at-plant soil application at 3 Ib/ai/A.  Samples must be collected  shortly after the second
       foliar  treatment  or at a PHI (hay) and pregrazing interval (vines) to be specified by the registrant.  Tests must
       be conducted in GA(49\),  FL(6%), NC(10\), and TX(8.5\) which together in 1984 produced 74% of  peanuts grown in
       the United States and account  for all major peanut production areas (Agricultural Statistic^,  1985. p. 121).
       As an alternative to submission of these data, the registrant may restrict grazing and feeding of vines and hay
       and request  revocation of these tolerances.

   36/ Data depicting  residues of oxamyl in the processed products meal, crude and refined oil,  and soapstock from
       peanuts bearing measurable,  weathered residues.  Should residues concentrate in any processed  product, food/feed
       additive  tolerances must be proposed.

   37/ Data depicting  oxamyl  residues in or on pineapple forage harvested immediately after the  last  application of the
       following tmtment schedule (using the 2 Ib/gal  SC/L formulation):   48 Ib/ai/A cumulative to  the  plant crop
f<      including 8  ll-'ji/A as a  broadcast soil application 1 week after planting followed by foliar applications at
       4 Ib/ai/A made  at 2- to 4-week intervals.  Tests  must be conducted in HI where ca. 100% of 1982 U.S. pineapples
       were produced  (1982 Census, of  Agriculture, Vol. 1, Part 51, p. 383).  Alternatively, the  registrant may impose
       a 14-day pregrazing restriction.

   38/ Data depicting  residues of oxamyl in juice processed from pineapples bearing measurable,  weathered residues.  If
       the data  indicate potential  for residue concentration, a food additive tolerance must be  proposed.

   39/ Data depicting  residues of oxamyl in or on green,  freshly harvested tobacco following preplant incorporated (PPI),
   ~~  transplant water, and  two foliar treatments at 6  Ib/ai/A, 0.5 Ib/ai/A, and 1 Ib/ai/A, respectively.  Tobacco
       plants must  be  transplanted  into treated soil within 1 week of PPI application.  Two foliar applications of the
       SC/L formulation  at 1  Ib/ai/A  with a suitable spreader^ sticker must be made to tobacco,  the first within 2 weeks
       of transplanting  and the second 2 to 3 weeks later.

-------
                                                        TABU-:  A

                                           GENERIC  DATA  REQUIREMENTS  FDR  OXAMYI,
Footnotes:

§158.12S Residue  Chemistry (cont'd)

40/ If oxamyl  residues of _>_ 0.1 ppm are detected  in  or  on  green,  freshly  harvested  tobacco,  data depicting residues
    in or on dried or cured tobacco will  be  required.   If  residues in or  on dried  or  cured  tobacco tire > 0.1  ppm,
    pyrolysis  products derived from the active  ingredient  must  be characterized  and  the  level  of the residue  in smoke
    must be quantified.  (('^ClOxamyl  must be used  for  identification of  pyrolysis  products.)

41/ Data depicting residues of oxamyl  in  or  on  fruit from  cherry,  peach,  or pi urn trees and  si  iwberry plants  treated
    with the 10\  G formulation at  20  Ib/ai/A postplant  and at 2 lb/ai/200 cjal/A  with  a spreader sticker in foliar
    applications.  Fruit must be harvested  1 year following the last treatment.  Should  residues be detected  in or
    on fruit following oxamyl treatment in a nonbearing year,  tolerances  must  be proposed.

42/ Presently,  the nature of the residue  in  animals  is  not adequately understood.  On receipt  of the requested animal
    metabolism studies, the need  for  the  nature of  tolerances for residues in  animal  commodities will be determined
    and  the  need  for additional  feeding studies evaluated.

43/ The  timeframe for the submission  of processing  studies is 24  months.

-------
                                                      TABLE B
                  PRODUCT  SPECIFIC  DATA REQUIREMENTS  FOR MANUFACTURING-USE PRODUCTS CONTAINING OXAMYL
 Data Requirement
  Test
Substance
 58.120 Product Chemistry
 'roduct Identity and Composition

 61-1 - Product Identity and Dis-
        closure of  Ingredients

 61-2 - Description of Beginning
          Materials and Manufacturing'
          Process

 61-3 - Discussion of Formation of
          Impurities

Analysis and Certification of
Product Ingredients

 62-1 - Preliminary Analysis

 62-2 - Certification of Limits

 62-3 - Analytical Methods to Verify
          Certified Limit
          >
Physical and Chemical Characteristics

 63-2 - Color

 63-3 - Physical State

 63-4 - Odor
     MP
     MP
     MP
     MP

     MP

     MP




     MP

     MP

     MP
Does EPA      Bibliographic
Have Data?!/  Citation I/
                                                                                           Must Additional  Timeframe
                                                                                           Data be             for
                                                                                          Submitted?       Submission2/
                                                         Yes
                                                         Yes
                                            Yes
                                            Yes

                                            Yes

                                            Yes
                                                          6 months
                                                          6 Months
                                                                       6 Months
Yes
Yes
Yes
12 Months
12 Months
12 Months
6 Months

6 Months

6 Months
oo

-------
                                                                   TABLE B
                           PRODUCT  SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING OXAMYL
vO
Data Requirement Test Does EPA Bibliographic Must Additional Timeframe
Substance Have Data?!/ Citation I/ Data be for
Submitted? Submit inn?/
158.120
Physica
(contl
63-7

63-12
63-14

63-15
63-16
63-17
63-18
63-19
63-20
Product Chemistry (continued)
1 and Chemical Characteristics
nued)
- Density, Bulk Density, or
Specific Gravity
- pH
- Oxidizing or Reducing
Ac v :' on
- Flammability
- Explodabil i ty
- Storage Stability
- Viscosity
- Miscibility
- Corrosion Characteristics



MP

MP
MP

MP
MP
MP
MP
MP
MP



Yes

Yes
Yes

Yes
Yes
Yes
Yes
Yes
Yes



6 Months

6 Months
6 Months

6 Months
6 Months
15 Months
6 Months
6 Months
15 Months
          I/  Although product  chemistry  data may have been submitted in the  past,  the Agency has determined that these data must
              be resubmitted  for  each  manufacturing-use product.   New requirements  have been introduced and previously submitted
              data must be updated.  Therefore,  bibliographic  citations  for the  old data are not applicable.
          21  Due dates refer to  the number of months following receipt  of  this  Registration Standard by the registrant, unless
              otherwise indicated.                                                     .
          3/  Formulation intermediates  are also included in the  category of  manufacturing-use products.

-------
                                                      TABLE B

                PRODUCT  SPECIFIC  DATA  REQUIREMENTS FOR MANUFACTURING-USE  PRODUCTS CONTAINING OXAMYL
)ata
Requirement Test Use Does EPA Bibliographic Must Additional Timeframe
Substance Patterns Have Data? Citation Data be for
Submitted? Submlsslonl
158.135 Toxicology
*CUTE TESTING:
31-1
U-2

91-3

91-4
91-5
31-6

- Acute Oral Toxlclty - Rat
- Acute Dermal Tt~ic1ty -
Rabbit
- Acute Inhalation Toxlclty -
Rat
- Eye Irritation-Rabbit
- Dermal Irritation-Rabbit
- Dermal Sensl tlzatlon-
Gulnea Pig
«
HP
MP

MP

MP
MP
MP

ABEF No
ABEF No

ABEF No

ABEF No
ABEF No
ABEF No

Yes 9 Months
Yes 9 Months

Yes 9 Months

Yes 9 Months
Yes 9 Months
Yes 9 Months

I/  Due *ttt refer to the nu-ber of •*«» f.ll«rl«« receipt  of  this Registration Standard by the re9istrant, unless

    otherwise Indicated.
 oo
 o

-------
                                                         TABLE C
                       PRODUCT  SPECIFIC DATA REQUIREMENTS FOR END-USE PRODUCTS  CONTAINING OXAMYL
Guideline  Citation and Name of  Test
  Test       Use     Does EPA     Bibliographic   Must Addi tional  Timeframe
Substance  Patterns  Have Data?!/ Citationl/      Data be            for

                                                                Submission?/
158.120 - Product Chemistry
Product Identity:
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Materials
and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
62-1 - Certification of Limits
62-3 - Analytical Methods to Verify
Certified Limit
>hys1cal and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
-- -. n 	 ft-., DnlL noncitv. or
EP
EP
EP

EP
EP
EP
EP
EP
EP
EP
ALL
ALL
ALL

ALL
ALL
ALL
ALL
ALL
ALL
ALL
juuiui nei
Yes
Yes
Yes

Yes
Yes
Yes
Yes
Yes
Yes
Yes
Jf 5UD
6 Months
6 Months
6 Months

12 Months
6 Months
6 Months
6 Months
6 Months
6 Months
6 Months
         "specific Gravity
     CO

-------
                                                        TABLE C
                       PRODUCT SPECIFIC DATA REQUIREMENTS FOR END-USE PRODUCTS CONTAINING  OXAMYL
Guideline Citation and Name of Test
  Test       Use     Does EPA     Bibliographic  Must Additional   Timeframe
Substance  Patterns  Have Data?!/  dtationl/     Data be           for
158.120 - Product Chemistry (continued)
Physical and Chemical Characteristics^
63-12 - pH
63-14 - Oxidizing or Reducing
Action
63-15 - Flammablllty
63-16 - Explodablllty
63-17 - Storage Stability
00&3-18 - Viscosity
63-19 - Mlsclblllty
63-20 - Corrosion Characteristics
63-21 - Dielectric F -nkdown Voltage
Other Requirements:
64-1 Submlttal of Samples EP.TGAI

ontini
EP
EP
EP
EP
EP
EP
EP
EP
EP
,PAI
have
ued)
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
ALL
Teen submitted in the pc
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Reserved3/
ist, the Agency has determined
JUUIIII ib 1 Ullil/
6 Months
6 Months
6 Months
6 Months
12 Months
6 Months
6 Months
6 Months
6 Months

that these data musi
I/  Al
3/
              tted  for each pestlcl
                                                                                                            . .....
                                                    them-

-------
                                                         TABLE C
                                           GENERIC DATA REQUIREMENTS FOR OXAMYL
Data Requirement
158. 135 Toxicology
ACUTE TESTING:
81-1 - Apute Oral Toxicity - Rat
81-2 - Acute Dermal Toxicity -
Test
Substance
10G
10G
Use
Patterns
ABEFHI
ABEFHI
Does EPA
Have Data?
No
No
Bibliographic Must Addi
Citation Data be
Submitted?
Yesl
Yesl
tional Time frame
for
Submission
9 Months
9 Months
         Rabbit

81-3  -  Acute Inhalation Toxicity -
         Rat
10G
ABEFHI
No
Yes
9 Months
  I/    These  data are  required  only  if  the  Toxicity Category  I and Restricted Use Classification are challenged  by   the
       registrant.   These   data   will   be waived  if the  registrant elects to restrict the  product and  utilize  Toxicity
       Category I labeling.
CD

-------
    APPENDIX  II
LABELING  APPENDICES
         84

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                               LABEL CONTENTS

      40  CFR 162.10  requires  that certain specific labeling  statements
 appear  at  certain  locations  on  the label.   This is  referred  to  as
 format labeling.    Specific label items listed below are  keyed to  the
 table at tne end  of  this  Appendix.

      Item 1.    PRODUCT  NAME -  The name, brand or trademark  is  required
 to  be  located on  the  front  panel,  preferably centered  in  the   upper
 part  of the panel.    The  name  of  a product will not be accepted  if   it
 is false or misleading.                                      "  ,

      Item  2.   COMPANY NAME  AND  ADDRESS - The name and address  of  the
 registrant  or  distributor is  required on the label.   .The  name  and
 address should  preferably be  located at the bottom of the front   panel
 or at the end of  the  label  text.

      Item  3.   NET  CONTENTS  -  A  net contents statement is required  on
 all   labels  or  on  the container of   the  pesticide.    The  preferred
 location  is  the   bottom of  the  front  panel  immediately  above  the
 company  name and address,  or  at the  end  of  the  label text.   The  net
 contents  must  be expressed in  the largest  suitable  unit,  e.g.,   "1
 pound  10  ounces"   rather  than "26 ounces."  In   addition  to  English
 units,   net contents   may  be  expres'sed in   metric  units.   [40  CFR
 162.10(d)]

      Item  4.   EPA   REGISTRATION  NUMBER  -  The   registration   number
 assigned  to  the  pesticide  product must appear on  the  label,  preceded
 by  the  phrase  "EPA   Registration  No.,"  or   "EPA   Reg.  No."   The
 registration number  must  be set in type of a  size  and  style similar to
 other print on  that  part  of the label  on which it  appears and must run
 parallel  to it.   The registration number  and the  required  identifying
 phrase   must  not   appear  in  such a manner as   to suggest  -or  imply
 recommendation  or  endorsement  of the  product by  the  Agency.  [40  CFR
 162.10(e)]

    Item 5.   EPA ESTABLISHMENT NUMBER  - The  EPA  establishment  number,
 preceded  by the phrase  "EPA Est." 1s  the final establishment  at  which
 the   product was  produced,  and may appear in any suitable  location  on
 the label  or immediate  container.    It must  also  appear  on  the  wrapper
 or outside  container  of the package  if the EPA establishment  number  on
 the immediate container cannot be clearly  read through* such wrapper  or
 container.  [40 CFR  162.10(f)]

    Item  6A.   INGREDIENTS  STATEMENT  -  An  ingredients   statement  is
 required   on the  front  panel.    The  ingredients  statement must  contain
 the   name and percentage   v weight  of  each active ingredient   and  the
 total    percentage  by we  jnt  of all  inert  ingredients.  The  preferred
 location   is  immediately  below the   product  name.   The  ingredients
 statement must  run parallel with,  and be  clearly distinguished  from,
other   text on  the panel.    It must  not be placed in the body of other
 text.    [40  CFR  162.10(g)]
                                            85

-------
     Item   68.   POUNDS PER GALLON STATEMENT  -  For  liquid  agricultural
 formulations,   the  pounds  per gallon  of  active   ingredient  must  be
 indicated  on  the label.

     Item   7.    FRONT  LABEL  PRECAUTIONARY  'STATEMENTS  - Front  panel
 precautionary statements must be grouped together,  preferably within a
 block   outline.    The  table  below  shows  the   minimum   type  size
 requirements  for various size labels.

     Size of Label        Signal Word          "Keep Out of  Reach
     on Front  Panel        Minimum Type Size       of Children"
     in Square Inches     All  Capitals          Minimum  Type Size

     5 and  under                6 point               6  point
     above  5 to  10             10 point               6  point
     above  10  to 15            12 point               8  point
     above  15  to 30            14 point              10  point
     over 30                   18 point              12  point

     Item 7A.  CHILD HAZARD WARNING STATEMENT - The statement
 KEEP  OUT  OF REACH OF CHILDREN  must be located on  the  front  panel
 above  the  signal   word  except where  contact  with  children   during
 distribution  or use is unlikely.  [40 CFR 162.10(h)(l ) (ii)]

     Item   7B.   SIGNAL WORD - The signal  word  (DANGER,  WARNING,   or
 CAUTION)   is  required on the front panel  immediately below the  child
 hazard warning  statement.  [40 CFR 162.10 (h)(l)(i)]

     Item   7C.   SKULL  & CROSSBONES AND WORD  "POISON"  - On  products
 assigned   a   toxicity  Category I on the basis  of  oral,  dermal,   or
 inhalation  toxicity.  the word "Poison" shall appear on the label   in
 red  on a background of distinctly contrasting color and the skull  'and
 crossbones  shall  appear in immediate proximity to the  word  POISON.
 [40  CFR 162.10(h)(l)(i)]

     Item   7D.   STATEMENT  OF  PRACTICAL TREATMENT  - A  statement  of
practical   treatment (first aid or other) shall appear on  the  label of
pesticide products 1n toxicity Categories I,  II,   and  III.    [40  CFR
162.10(h)(l)(111)]

     Item  7E.   REFERRAL STATEMENT - The  statement "See  Side(or  Back)
Panel  for  Additional  Precautionary  Statements"  is  required   on   the
front  panel   for  all products,  unless  all   required   precautionary
statements appear on the front panel.  [40 CFR 162.10(h)(l )(iii)]

     Item   8.     STn.E/BACK    PANEL    PRECAUTIONARY   LABELING   - The
precautionary   sta* •...•ents  listed below must  appear  together   on   the
label  under  the heading "PRECAUTIONARY  STATEMENTS."    The  preferred
location   is  at  the  top of  the side or  back   panel   preceding  the
directions  for  use,  and   it is preferred that these  statements  be
surrounded  by  a block outline.    Each  of  the   three  hazard  warning
statements  must be headed by  the appropriate hazard title.   [40  CFR
162.10(h)(2)J.


                                 86

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     Item  8A.   HAZARD  TO  HUMANS  AND DOMESTIC ANIMALS -  Where  a  hazard
 exists  to humans or domestic  animals,  precautionary  statements   are
 required  indicating the  particular hazard,  the route(s)  of   exposure
 and  the precautions to be taken  to avoid accident,  injury  or damage.
 [40 CFR 162.10(h)(2)(i )]

     Item  8B.   ENVIRONMENTAL  HAZARD - Where a hazard exists   to  non-
 target organisms excluding humans and  domestic animals,   precautionary
 statements  are   required   stating the nature of the  hazard  and   the
 appropriate   precautions   to   avoid  potential  accident,   injury,  or
 damage.   [40  CFR 162.10(h )(2)(ii )]

     Item  8C.     PHYSICAL  OR   CHEMICAL  HAZARD   - FLAMMABILITY
 Precautionary  statements   relating to f1ammabi1ity of a  product   are
 required  to   appear on   the  label if it meets the  criteria  in   the"
 PHYS/CHEM Labeling Appendix.   The requirement  is based on the  results
 of  the flashpoint determinations  and flame extension tests required to
 be  submitted  for all  products.    These statements  are to be located in
 the side/back panel  precautionary statements section,  preceded by the
 heading "Physical/Chemical  Hazards."   Note that no signal  word  is  used
 in  conjunction with  the f 1 armabi 1 i ty statements.

     Item 9A.   RESTRICTED  USE CLASSIFICATION  -  FIFRA  sec. 3(d)  requires
 that   all  pesticide  formulations/uses  be cl assi f ied-for either  general
 or   restricted   use.    Products  classified for restricted use  -may  be
 limited  to use by certified applicators or persons under  their  direct
 supervision   (or  may   be  subject to other restrictions   that  may  be
 imposed  by regulation).

     In  the Registration Standard, the  Agency has  (1)  indicated  certain
 formulations/uses  are  to  be restricted  (Section  IV  indicates why  the
 product   has  been classified for  restricted  use);   or  (2) reserved  any
 classification decision until  appropriate  data are submitted.

    The   Regulatory   Position  and Rationale   states  whether   products
 containing this active ingredient are classified  for restricted   use.
 If  they  are  restricted the draft label(s)  submitted to the  Agency  as
 part of your  application  must  reflect  this  determination  (see below).

     If  you  do  not  believe that  your  product should be classified for
 restricted use,   you must submit any  information  and  rationale   with
your  application for reregistrati on.    During the Agency's review  of
your  application,   your  proposed classification   determination will be
evaluated  1n  accordance with the  provisions  of 40  CFR 162.11(c).    You
will be  notified of  the Agency's  classification decision.
                                            87

-------
      Classification Labeling Requirements
      If  your  product has been classified   for   restricted  use,  the
 following  label requirements apply:

      1.  All uses restricted.

         a.  The statement "Restricted Use  Pesticide"  must
      appear at the top of the front panel  of the  label.   The
      statement must be set in type of the  same  minimum size
      as  required for human hazard signal  word (see  table  in 40
      CFR 162.10(h)(l)(iv)

         b.  Directly below this statement  on the front panel,
      a summary statement of the terms of  restriction  must
      appear (including the reasons for restriction  if specified
      in  Section I).  If use is restricted  to certified applicators,
      the following statement is required:   "For retail sale
      to  and use only by Certified Applicators or  persons
      under their direct supervision and only for  those uses
      covered by the Certified Applicator's  Certification."

      2.  Some but not all uses restricted.   If the Regulatory
Position and Rationale states that some uses are  classified
for restricted use, and some are unclassified,  several courses
of action  are available:

           a.  You may label the product for Restricted use.
      If you do so, you may include on the label uses  that
      are unrestricted, but you may not distinguish them
      on  the label  as being unrestricted.

           b.  You may delete all restricted uses from your
      label  and submit draft labeling bearing only unrestricted
      uses.

          c.  You may "split" your registration, i.e., register
      two separate products with identical formulations,  one
      bearing only unrestricted uses, and the other bearing
      restricted uses.  To do so,  submit two  applications for
      reregistrati on, each containing all forms and necessary
      labels.  Botti applications should be submitted  simul-
      taneously.  Note that the products will be  assigned
      separate registration numbers.

    Item  98.    MISUSE   STATEMENT -  All products must bear  the   misuse
statement,   "It is a violation of Federal  law  to use this  product in a
manner inconsistent with  its labeling."  This  statement  appears at the
beginning of the directions  for use,   directly beneath the heading  of
that  section.
                                    88

-------
     Item   10A.   REENTRY  STATEMENT - If a reentry  interval  has  been
 established   by  the  Agency,  it  must  be  included   on   the  label.
 Additional  worker protection statements may be required  in  accordance
 with  PR Notice 83-2, March 29, 1983.

     Item  108.   STORAGE AND DISPOSAL BLOCK -  All  labels  are   required
 to   bear   storage  and  disposal   statements.   These   statements   are
 developed  for specific containers, sizes, and chemical  content.  These
 instructions must be grouped and appear under the heading "Storage  and
 Disposal"  in the directions for use.   This heading must  be set  in  the
 same  type sizes as required for the child hazard warning.  -Refer   to
 Appendix  II, STOR,  PEST/DIS, and CONT/DIS to determine the storage  and
 disposal  instructions appropriate for your products.

     Item  IOC.   DIRECTIONS FOR USE - Directions for use must be  stated
 in terms which can be easily read and understood by the average  person
 likely  to  use  or  to supervise the  use  of  the  pesticide.    When
 followed,  directions must be adequate to protect the public from fraud
 and   from  personal  injury and to prevent unreasonable adverse  effects
 on the environment.  [40 CFR 162.10]


                     COLLATERAL LABELING

    Bulletins, leaflets, circulars,  brochures,  data sheets, flyers, or
other  written  or graphic printed matter which  is  referred to on   the
label  or  which  is to accompany the product   are  termed  collateral
labeling.   Such labeling may not bear  claims  or representations   that
differ   in   substance  from  those  accepted   in    connection    with
registration  of the product.   It  should  be made  part of the response
to this notice and submitted for  review.
                                89

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O
                                                   SUMMARY-6
                                 LABELING REQUIREMENTS OF THE FIFRA,  AS AMENDED

lEM
1
7
3
4
b
;A
>B
7

'A
^

LABEL ELEMENT
Product name
Company name
and address
Net contents
EPA Reg. No.
EPA Fst. No.
Ingredients
statement
Pounds/gal ion
statement
F ront panel ""*
precautionary
s i a iciucii Li 	 ^^__^
Keep uut of Reach
of Children
(Child hazard
warning) _t
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
AIT products
AIT products
Liquid products
where dosage
given as Ibs.
ai/unit area
All products
11 n rf\(\l\C f Q

All products
PLACEMENT
REQUIRED
Front panel
None
None
None
None
FVont panel '
•ront panel
Front panel
Front panel

^ Front panel
ON LABEL
PREFERRED
Center front
pane)
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel ,
immediately
before or
fol lowing
Reg. No.
Immediately
following
product name
nrectly below
the main
ingredients
statement

Above signal
word
Immediately
below child
hazard
warning

COMMENTS

Tf registrant is not the producer, must
be qualified by "Packed for . . ..'
"Distributed by. . .," etc.
May be in metric units in addition to
U.S. units
Must be in similar type size and run
parallel to other type.
May appear on the container instead of
the label.
ext must run parallel with other text
on the panel .

All front panel precautionary statements
must be grouped together, preferably
blocked.
Note type size requirements.

Note type size requirements.

-------
SUMMARY-7




J
vO

\
i



i

LAbtL LLtMLNI
bKui I & cross-
bones and word
POISON (in red)
Statement of '
Practical
Treatment or
First Aid
Referral
statement
Side/back panel
precautionary
statements
' Hazards to
humans and
domestic
animals
~Tnvi ronmenta 1
hazards
	 • 	

APPLICABILITY

OF REQUIREMENT
AI i products
which are Cat-
egory I based
on oral , der-
mal , or inhala-
tion toxlclty
1 All products
in Categories
I, II. and III
All products
where pre-
cautionary
label ing
appears on
other than
front panel .
All products
All products
in Categories
I, II. and III
TTTl products
	 • —

PLACEMENT

HLIJU1HLD
l-ront panel
1 Category I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped wi th
side panel
precauti onary
statements.
Front panel
None
None
None
	 	 	 • 	 •

UN LAULL

PKLI-LRRED
Both in close
proximity to
signal word
Front panel
for all .

Top or side
of back panel
preceding
di recti ons
for use
Same as above
Same as above


i — 	 	

COMMENTS




Must be grouped under the Headings in
8A, 8B. and 8C; preferably blocked.
Must be preceded by appropriate signal
word.
Environmental hazards include Dee
caution where applicable.



-------
SUMMARY-8
rr u
1 LM
IL
JA
9B
IUA
IUB
roc—

LABLL ELEMENI
*nysical or
chemical
hazards
Restricted
block
Misuse
statement
Reentry
statement
Storage and
disposal block
Directions
for use
1 APPLICABILITY 	
OF REQUIREMENT
All pressurized
products, others
with flash
points under
150~F
All restricted
products
All products
*
PR Notice 83-Z
or as determined
by the Agency
All products
All products
1 PLACEMENT
REQUIRED
None
Top center
of front
panel
Immediately
following
heading of
directions
for use
In the
directions
for use
In the '
directions
for use
None
ON LABEL
PHLhERRED
Same as above
Preferably
blocked

Immediately
after misuse
statement
Immediately
before
specific
directions
for use or
at the end of
directions
for use
None

COMMENTS
Refer to Appendix II guide
PHYS/CHEM
Includes a statement of the terms of
restriction. The words "RESTRICTED USE
PESTICIDE" must be same type size as
signal word.
Required statement is:
"It is a violation of Federal law
to use this product in a manner
inconsistent with its labeling."

Must be set apart and clearly distin-
guishable from from other directions
for use.
Refer to Appendix II guides STOR,
CONT/DIS, and PEST/DIS for further
information and required statements.
May be in metric as well as U.S. units

-------
P*t CAUTION AMY (TAIEMCN7B


  HAXAA04 TO HUMANS

  |1 DOUESTC
 ENVMXUf MTAL KAZAN*
 pwr*c,v O

    HA2AAM
  Kf-CMTKY fTATf UlNl
  STORAGE AND
  '  DISPOSAL
    RESTRICTED USE

        PESTICIDE
    (jreaaon for clnsnlfylnr)
ICtAIL S*J TO AWD LBt CKLI IT CWTlna) WfTICATOKi OK
 « «MDCX IMtU 01MCT iUPnrvuiON MO ONLf fC« HCbE
 OVOW) IT THE CZXTIMtO AmjCATWi CtKTlfJCATICW
     PRODUCT
         NAME
                          ACTIVE NOHEOCNT:

                          HIK1 NOACMNT*


                          TOTAL:
                                             100 00 \
                          Txa rnoovxi COHTAMJ  LM or  fEN cuuow
                         KEEP OUT OF REACH OF CHILDREN

                            DANGER —POISON
     •TATIUCNT Of ffUCTCAt. THfATUINT
                        M IYIS
                      Ml U)ff PANEL fOU AOOmOMAL PMCAUDONXNV 9TAUUENTS
                      UFO ir:

                      TOWN. >TATI

                      IJTAKJJMUINT NO =

                      If A RCOOTnATION NO
                                NET CONTENTS:
                                                            CHOP:
                                                            CttOf:
                                    cnor.
                                    ChOf.
                                                               WAfWANTY fTATOOKT

-------
          (1AUMIK1*
   HAIAItt* TO HUUAJU
   * OOMEfTC ANMAU
       CAUTION
        ^", A4. HATAMM
     HA2AMM
I • •
      * •
   9U-CMTHV 9TATIMCMT
 one*-..
                              PRODUCT
                                   NAME
                           ACTNt MOflCOOtt:
                               MOAUXMT*
                            IOIAU
                                               10000%
                            TM» PRODUCT COMTAMS  LM Of  n* OAU.OM
                          KEEP OUT OF REACH OF CHILDREN
                                 CAUTION
                               fTATCUINT Of PHACnCAL TRCATU£NT
» MHAUO
r ON »KMI
f N It It

•ci tot f Awet ro* AOomoMAi
                                                 ITATIUEMU
                        TOWN. ITATI ;
                        UTAIUSHUtMT NO. =
                        (FA ftf (MIRATION MX :
                                 NCT CONTENT*:
                                                               CAOT:
                                                               CAOT:
                                                               CHOP:
                                         STORAGE AND
                                           DISPOSAL
                                                                •10/1x01 =
                                                                 WAIWAMIYITATUICNT

-------
   it obtained Us* 4tn from moth?
     (idfodtyr, aooUcant copied
     » publication: applicant oat
    37 or th* data tram EPA).
     Tn* applicant «*«n submit
     ppUcutloa i stAtoncnt that
     ^er*lu*aoQ or th* prop«ru«
     iaad  taTrcy or th*  formv
?nd-ua*  product.  ™«r QOC cotm
         niDportln*
ezcep< \.h* foUovtn* <
  (1) TO* data
mltt*d t\ EPA nm-Uf p*r»4Ta£a (b) or
thu »*ca
  (3)  OtHfcr  ^«>«  p*rtalni£c  to
aJrty or fc* product'i act
enu. r»th*k. than to th* i^frty or tii*
end-u**  p
  (3) »^Tl»^n^ tolcmaea. /ood
             tztmpUonj/  iad  other
cl
Tood. Onic. idy Cocmei^c Act.
  (•) U en* tci
lUm of d*t*
McCoa v«j n
P«DM or) 1QO<
ly submitted tho'
pr^dtcesaor. U3O^

for  rtdnrvooo.
p«rmlt. or  inw
OM to &a *i
                        n >>»•> my
                         andrr tiu
                    37 (or u th* tz-

                     to EPA (or !U
                  'oa or i/ter Jinu-
                      in iflpilcaUon
rvAcn*d  vrlt
xmount ud :$• :ermj
407 came
tbl*     und«
J(cxixDxu)/witn
or the tppii'Lt'KA  S*cQon  3(cKl) of  t
                                     product  .rith cotnpoeiuon mdVnund-
                                        •di«j/dentlcal  to tho«* propoaed (or
                                           •pUcant'i  product.  undeJy.  th*
                                                  lenu  In  etfect oo\Ui*
                                     dat*/EPA  approTc*  th*  appllca^fi
                                     prt**xu  application.
                                      24CL j. t. '"^ U
                                     0-1C 114 it M«.)
                                     rv« rn n»ii MA/
                                                      FTTRA. u
                                                    11. irrti
                                     I 1IZ.19  Lt*«ltn« n^ulrtm«iiu.

                                       (»J  GrarraJ — (1)  C&ntmU  o/
                                     Uo«t Crvrr  p«*ttdd«  producu
                                     cioa ip*dlled by th« Act ind <_h«
                                     '.iuooj ji  thli PVTL The «nunu 3f t
                                     1*0*1  muit  ino« cl**/Ly  md promi-
                                     nently in* follovuic:
                                       M)  The  aim*, onnd. or U-idcsuurt
                                     'in'I^T wruch t_ne product J told u prt-
                                     >cnb*d  la P*TMTVO&  «6)  or  Uui v*c-
                                     uoa:
                                       iU)  Th* nun* md  iddrca of '.ft*
                                     producer.  r*TUtrvnt   or  p*rson  for
                                     wQom produced u presented la  ;«JT^-
                                     cnpa (. o  of  taai Mcaoa:
                                       (Ul) T.i act connjiu u prtv3-.!>*d
                                                    j of '-tui
                                        95

-------
| 142.10

  (Iv)   The    product   registration
number a* prescribed In paragraph (e>
ol Ihla section;
  (v>  The  producing  aatabtlahment
number a* prescribed In paragraph (f)
ol thta arctlon;
  4*1) An Ingredient statement M pr»-
arrlbed In paragraph <•> ol this aec-
Uon;
  Ivll) Warning or precautionary state-
anenU aa prescribed In paragraph 
ol Ihla aecllon;
  <*llll The direction* for usw a* prw-
•crlbed In paragraph II) ol Ihte aecUon:
and
  (U> The taat elaaaffleaUortfa) M pra-
actlbcd In paragraph ()> ol thta section.
  (1) rromUeMce aitsT lerlMJIfa. (I) AH
worda. •laUmenla. graphic rrpreaenla-
Uona. dealgna or other Information re-
quired on the labeling bjr UM  Act or
the regulation* In  Into part mart  b*
clearly Will hie to a petaon with normal
vUkm, and must be placed with guch
cotmplcttoiigixaa  (M compered  with
other word*.  •lalrmenta, designs,  or
graphic  matter  on th« Ubellrtf) and
expressed In mich tern.  *  to render It
likely lo be re«4 and  _/»derstood  by
the ordinary Individual under custom-
ary conditions of purchase and uae.
  (II) All required label te«t mual:
  (A) Be  art In ••point or tarter type".
  (B) Appear  on a clear conlragUng
background; and
   Hot he obacured or tio»dod.
  IJ) L+*ru**e to 6e tued. All required
Ubcl or  labclln« lei I snail appear In
In*  Khgilah  rancuagr  However. th«
Airencr may require or UM  applicant
may  pvopoat additional Uit In other
language* M fa cona+dered neoaaaary to
protect the  public.  When  additional
leit In another language  to neceawary.
•II  labeling retiulremenU win be  ap-
plied equally to  both the English and
other language veralorsi of  lh« label-
In*.
  14)  naremmf  o/ L«o«i-4h Otntr+L
The label shall appear on  or b« aecure-
|y attached to the Immediate contain-
er of the poattcM* product, for  pur
poaea of thta Section, and UM  mta-
brandmg provtolona of the  Act, "se-
curely  attached"  shall mean that  a
label «u» r«wonably  be r«p«eU>d U»
 rrmkln •lllm«4 <«uftn« th* loif»««»b>«>
TlrU 40—rr*l*ctl»«i «f
 wrapper or ouUrtde container through
 which the label cannot be clearly read.
 Ihe  label muat  atao  be securely at-
 tached lo guch oulatde wrapper or con-
 Ulner. If It • a part of Ihe package a*
 cuatomarlly distributed or sold.
   (Ill Tank  car*  ana*  offr  bmtk  eon-
 fafner*— Anr
                                                                     Oovrrn
                  or devlccr.
                           or Indl-
  any  agency ol  the
  ment;
    (•I) The name ol a pmttaMe which
  contain* I wo or  more principal actlte
  ln«rrdlrnt« If  (he  narnr Ku««rnU one
  or more bill  not  all  such  principal
  active  InnrrdlrnU  even lhou«h the
  nurnr* ol Ihr other  Ingrrdlrntn «rr
  KUted rlwrvhrrr  In the Ubrlln*:
   (*lll A (rue xlolrmrnt iinrd In Much a
  way a* U> »l»e » lulur or ml'lrt toxic rhrml
 caU known"
   «C> •Tolhillon approved"
   (•) Final prlnlrd tabrltny (I) Excepl
 a* provided In  paragraph (aM6Nll) of
 thta  arctkm.  final  printed   labeling
 itiuxt br gubmlttcd and arcrptrd prior
 lo regbrtratlon.  However, final printed
 labeling nr*d not be aubmlltpd unlit
 draft label lr*U have been provision-
 ally accepted by the Agency.
  (II) Clearly  legible reproduction* or
 photo reduction* will be accepted  for
 untwual  label*  *uch a*  thone *llk-
 it.ie>iKd directly onto  gla** or metal
 container* or large bag or drum labels.
 auch reproduction* mu*t be of micro-
 film reproduction quality.
  (b) Hamf. brand, or trattrmarlt. (I)
 The name, brand,  or trademark under
 whkh  Ihe pentlclde  product  In sold
iihall apnear on  the front panel of (he
 label
  (3) No name,  brand,  or trademark
may appe*r on the litbcl which:
  (I) In (nine or mlnlemllna. or
  (II) 1 1 a* nol been  approved by the
Administrator  tliroimh rr«l«lr»llon or
              •
                              5 Ul 10

    (c) Name and  addrm ol producer.
   registrant, or person  lor  whom pio
   dured  An unqualified namr nod »d
   drr-w given on Ihr laln-l  ulinll br ron
   sldered a* Ihe numr mid addre*a of Ihr
   producer. II Ihr rrglalranl  n namr up
   pear* on the Uhrl »nd the rrsHlrnul In
   nol the producer, or II (he nnmr ol Ihr
   person  lor  vhom Ihe  prsllrldr won
   prodtK-rd *ppenrr< on Ihr  lahel. II mu-/<>
  durer.
    Id)  Hrt tprloht or  mri«nrr o/ ron
  If nit  (I) The nrl weight or mrimmr
  of content »h*ll  he enchi^lvr ol *rni>
  per*  or other  motrrliOi and nh»ll br
  Ihr airrraiie conlrnl  unlrni rupllrllly
  slated M a minimum qtinnllly.
    (7> II the pcflllrldr I* a  liquid  Ihr
  net content  nlalrmrnl  shall hr In
  (ermed In metric unit*.
   (•)  Varlallon above  minimum  eon
 lenl or around  an average la permlwl
 ble only lo  Ihe exlenl  thai II rrprr
 sent*  deflation unavoidable In  good
 manufacturing   practice    Vnrlnllon
 below  a staled minimum I* nol permll
 ted. In no ca*e  shall  Ihe average ron
 lent of the packages In a shlpmrnl (nil
 below Ihe slaled arerane content.
   (e)  Product   rrpiilrallnn  numhrr
 The reglstrallon numher a*.*lgnrd lo
 the pesticide product  at the lime of
 registration shall appear on the Inhrl.
 preceded  by  the phra.*e  "r7fM  nr«N
 tration No.." or the phr«-*r  "FPA (!«•«
 Ho " The  reglntrollon numrwr xlmll ttr
•rt In type or • flfr »nd olylr xlmli*r in

-------
I !»*..•
      to  1C The rcfftaUmUon  number
     UM  required  idenUlyin*  phraae
ahaJI not appear hi *oeh a manner u
U »umM or  Umply recommendation
or endorse meitt of the product by UM
A««ncy.
        • •mber. The producto*
Ibhment  redatrallon number preced-
ed by  lh« phraae "KPA •«*.". of UM
final eetAbibhment at which UM prod-
uct WM produced may  appear In any
•ullabie location on the label or hmmt
dlaU onnUJner. It must appear on UM
wrapper or ouUkfa  container ol UM
package If the KPA e*Ublbhm«nt reg-
istration  number on  the ImmsJUU
container  cannot   be  dearly
through such wrapper or container.
                          -         -
el The label of each peatidd* product
must bear a •Utemenl which contain*
Lh« name and percentage by weight of
each  active Ingredient, the total per-
oenlage by weight of all Inert ln«rtxM-
enU:  and If the pesticide  contain* ar-
senic In any form, a statement of th«
percentages of total  and water -voluble
arsenic calculated  as  ekmenlal ar-
•enle. The active Ingredients  must be
designated by the term "active Ingredi-
ents" and the Inert Ingredients by the
term "Inert IngredlenU." or the slngu-
lar forms of thes* terms when appro-
priate.  Roth  term*  shall be  In  the
same type (toe. be aliened to the came
margin and be equally  prominent Ttve
statement "Inert Ingredients, none" I*
not required for pesticide* which con-
tain  IM  percent active  Ingredients.
Union the Ingredient statement b a
complete analysis of the pe*Udde. U»e
term "analysis" shall not  be uaed as a
neadlnc for th« Incredlent (tatement.
  «1) fofitlom oj infrtdUnl $UUm*nL
(I) The Ingredient etaUmenl  I* nor-
mally required on the  front panel of
the Ubrl. If ther  ., an  ouUlde con-
tainer or  wrapper  />vu«h which Ine
Inrredlent •UOemenl cannot be clearly
read,  the Inaredlent vUlenkent mu«t
kteo  appear on «uch ouUlde container
or  wrapper. If U>e «tae  or form of U»e
p»ck*«e  make*  It  Impracticable  to
pUce the ln«redlenl ctatement on the
rrool panel of  the  label, perrotarion
may  be  (ir«jiU>d  for  the  Incredlenl
rUUmenl to appear  etoewhere.
                                          TKU
  »  ->«^ rw«  parallel with  other
Umt on UM panel on which M. appeara,
and muwl  be dearly  dMIncukhable
from  and muwl  not be placed In the
body of other text
  <1)  Name* to be »Mrf  U im*r*dUnt
ttaUmenl. The name woed for each bv
•redlent   ahall   be  UM   accepted
common  name.  If  there h  one. fol-
lownt by  UM chemical name. The
commort name may be  imtd alone only
U It b well known. If no wimmon name
ha« been  eMabttahed. the  chemical
name alone aball be UM>d. In no can
wtU the UM •* a trademark or propri-
etary  name be permitted unlcm «uch
      ha« been accepted a* a common
name by UM AdmJnbtralor  vnder the
authority of Section »l«iUncanUy.
the product murt bear  the  following
•tatement wt a prominent porilion on
the label: "Hot  for  mie or  UK  alter
(date)."
  (II)  The product mimt meet all label
claim* up to the expiration  lime IndJ
catcd on the UbeL
  <7>  Imfrt i**Tf4tr*U. The Admlrsta
tralor may require the  nao*e of any
                                                                                                            •I rVe4*ctte«
   Inert ln«redlenU*> to be Ibied In the
   Ingredient •Utement If he determine*
   that  auch IncredlenUi) may poae  a
   hjLxard to nuui or thr environment.
    (h)  Wmmlmfft  u*4  »rece>floa«r|r
   it*tfwif»Li. Required   wamlnm and
   precautionary •tatemenU  concernlnf
   the  grneral  area* of  toxlcolocloal
   hazard Includlrwi hazard to children,
  environmental hazard, and  phymical or
  chemical hazard fall Into two troop*;
  thoee required on the  front panel of
  the labrllnc and thow which  may
                                                                    9
   appear  cbewhere.  8prririr       i
   menU ooinccmlnc content. pUornvi
   type atee. and promlnmrr »rr «l*
   below.
     (I) Kf^ulrnd front p**H iltlrmrn
   With  the  exception  of  Uir  clil
   hazard wamlnc •tatrmrnt. Ihr lr»( i
   quired on the front fux*! of Ihr Uti
   b determined by UK ToiMly  Cnlrii
   ry of the peoUdde. Tli^ r»lr«ory U •
   tlgnaS on the b«*b  of Uir  lilnlir
   hazard chown by any of irw Imltotln
   In the Uble below-.
   (I) Humun  limJtrd ilffmal loonf—
 Toiicilf Category I. All pesticide prod-
 uct! nveeUni the criteria of Toxldty
 Catefory  I ahall bear on the front
 panel the dmal word "Dancer." In ad-
 dition If the  product wa* amlfned to
 ToikUy Category I  on the bad* of IU
 oral. Inhalation or dermal toxldty (a*
 dbllnct  from akin and eye local ef-
 fecU) the  word "Pobon"  shall  appear
 In  rrd on  a background  of dbllnctly
 conlnuitln« color  and the ukull  and
 crombofMii chall appear In Inunedlate
 proximity to lh« word "poi*on.~
  (HI TarlcHw Cuttyorv II. All peatl-
 cMe product!  meeting the criteria of
 ToxvcUy  CaUgory II chall bear  on  the
 front panel the ilgnal  word "Warn-
 ing "
  (C> ToHcl/r C*Uyont III. All pertl-
 cMe product!  meeting the criteria of
 Toxklty  Category HI ihall bear  on
 the front (wuml the ilgnal  word "Cau-
 tkjn "
  (U) ToiMtr Ctleyor* IV. All peeti-
ckV prodixrU  meeting the criteria of
Toik-lly CiUgory IV ihall  bear on the
front panel the iUgn«l word "Caution."
  (E) Vtf of il(naj iponli.  Umt of any
-|«iij>l worcMi) uotodaled with a hUher
  Toxldly Category  b  not primllUxi
  except  when  the  Agency drU-rmlnr*
  that cuch labeling b nrrtmty to prr
  vent unreasonable advrrw rffrcU on
  rn«n or the envlrorunrnL -In no  nuie
  •hall  more than one human  huwrd
  •ignal word appear on the front porwl
  of a UbeL
   (II) OiU AaMrrf wmnftmf Rvrry  pr»
  Uc*de product  label ihall bmr on  the
  front panel the *i«ly
 the applicant to be cxtrrmrly rrmotr.
 or If the  nature of the pe>tlcin thr front
 panel of the label of all prattcMm mil
 big hi to  ToMWljr Calrwory I on thr
 bub of oral. Uihalatlon or dermal U»
Idly.  The   Agency  nu>y.  ho*r*rr.
prrmvlt reaaonabie varUiUona  In Ihr
         of th« «4jil«-in«^i( ol i.i«ril

-------
CO
          | 10.10

          c»l treatment I*  acme reference tueh
          as "Bee statement of practical treat-
          ment  on beck panel" appear* on  the
          front  panel nea/ the word "Poleon"
          and the skull and cronsborvea.
            (B)  OU»tr  (orlciCr eefeoorU*.  The
          statement of practical treatment U not
          required on the Iron I panel except a*
          described In paragraph IhKIHIIIMA) of
          IhU •ecllon. The applicant may. how-
          ever. Include *uch a front panel atate-
          menl  at  hU  option. Statement*  of
          practical treatment art,  hoarever. re-
          quired elsewhere  on  th«  label  In
          accord with paragraph (hHJ) of  ttito
          •ectlon If  they do  not appear on  the
          front panel.
           llv»  Placemen <  ana* JTOmlsKWCc.  All
          the require front panel warning vtate-
          ments *hall be  grouped  together on
          the label, and shall appear with «utfV
          clent  prominence  relative  to other
          front panel text and  graphic material
          to  make them  unlikely  to be over-
          looked under customary oondlUone of
          purchase and u*e The following table
          «how« the  minimum trpe stee require
          menu for  the  front panel  warning
          statement* on various sixee of labekr
        40—f>r*re«rUfl ef Efrvwvmwtenl
 * vrf.
     ••*)*..
 _ J
                                   It
                                   II
  (1) Other rtwvlrrrf verwfnp* an*" pre-
 cenfloita.ry ttmtrwtfntt. Th«i warnings
 and  precautionary  statement* a* re-
 quired below thall appear together on
 the label  under the general  heading
 "Precautionary   Statement*"   and
 under  appropriate  nibheadlng*   of
 "Haaard t« Humane and" Domestic Anl-
 male,**  " Environmental Hazard" and
 "Fhyvkml or Chemical Hazard."
  (ll  J/aMwnf to nameft* **4 tomtttic
 m*lm*U. (A) Where • hacard eiUU to
 humane or dumeaUc animal*, precau-
 Uonary etatetnenU are required Indl
 caUnc  the particular  hazard,  the
 routed) of eipocure and the precau-
 Uone to be taken to  avoid accident.
 Injury or  damajre. The precautionary
 paragraph  •hall be Immediately pre-
 ceded by the appropriate hazard
                                                   (B) The fottowlnn table depict* typi-
                                                 cal  precautionary  •tatemenU.  Thaw
                                                 •ialemenU  mivt be  modified or ex-
                                                 panded to reflect *p«clftc haxard*.
                    yy •*•! 0« MI sri to «r«* ••
                                                 tl

                  IM.
                                     . Where a
         hazard ckUU to rton tarvet onranlame
         eicludln*  humane  and domeeUc ani-
         mal*, precautionary etatententa are re-
         quired *lalln|  the  nature  of  Ui«
                 and  IHe a(>i>rof>rtat« P€«C»U-
                 to   »»old
Injury  or  damage. Kiamptea of  the
haxard *tatemenU and the  circum-
stance* under which they are required
follow:
  (A) If a peatldde Intended for out-
door uve contain* an actl** ln*re Por U*e«i InvoUIn* lollur Mppllrx
   lion to agricultural  rrnrM. Inrrnln. or
   nh*de  tree*,  or for mo*qnllo  ohnlr
   menl trralmenl*.  pmllcldrn  Inilr In
   polllnntlnx Irveclx mu^l hcur npproprl
   •Ic litbcl rnullorw
    (F) For all  outdoor n«r" other limn
   unuKtlc  appllcatlonii  the  l«rx-l  muni
   brnr the caution "Keep out of Inker
   pond* or Hlreitrn*. Do not ronlnmliiRlr
   »i»(rr br clennlnx of eniilpmrnl  or din
   poanl of wa.ite«."
    (Ill) /Vivifcaf or chrmlral ftarnnli
   W»rnln« uliitemenl* nil the Hwrnmnhll
   Ity or exploaUe chararl^rlnllm nf Ihe
           »re required an follown
                                        •. •<• OP-I tew Do «M pwctw. f fcfc«M.
                                                                                                                               a~.  0» « pram . krt,.^.
                                                                                                                               »»*.M.M ««« in- r ~r ..„.
   (I) DlrrcHoni  /or  l/ie—(I) Ofnerat
 rrqutremtnti—(I) Xtteouacv  and clar-
 ity  of  Atnctlont.  Direction* for  u*e
 must be staled In terms which can be
 easily  read  and  understood by  the
 average person likely to u*« or to *u-
 pervlse the use of the peiillclde. When
 followed, direction* must be adequate
 to protect Ihe public frorq fraud $nd
 from personal Injury and to prevent
 unreasonable adverse effect* on the
 environment.
  (II) Placrmmt of direction* /or tut.
 Directions may appear on any portion
 of the  label provided that  they are
 conspicuous enouith to be easily read
 by the  user of the pesticide product.
 Directions for UAC  may appear  on
printed  or »r«phlc matter which ac-
comp*nln the ixntlclde pro»lrf«* thmt:
   (A) If required by the Aienry. nuch
 printed or «rnphlc matter Is securely
 •llached to each packace of  the pext)
 clde.  or placed within  the  oulxlde
 wrapper or DM:
   (R) The label bear*  a  reference to
 the direction* for use In acrtrnipsnyln*;
 leaflet* or circular*, sttch as "Ree di-
 rection* In the enclosed circular:" and
   (C)  The Administrator  determines
 that It I* not necessary for such direr-
 lion* to appear on the label.
   (Ill)  Stceptloni  to  regalrrmenf /or
 rffrecffon for •*«— Detailed direc-
 tion* for uae  may be omitted from la-
 beling of pesticides whlrh arc Intended
 for use only by manufacturers ol ttrmt-
uets other than potlclde pnxtiM-ix l>>
thrlr regular manif/actwrlnir

-------
5 142.10

  (I) The label clearly §how« thai UMJ
product  U  intended  lor UM  only tn
manufacturing, proctsm* and sped fie*
the tvpe  The product  will not  come  Into
the hand* ol the general publk eioept
alter Incorporation Into (Intoned prod-
ucU;  and
>   («) The   AdmlnUtrator  determine*
that  «uch directions are not nrrngairj
to prevent  unreasonable adverse ef-
 fects on man or the environment.
   (B) Detailed direction* (or  u*e  may
 be omitted  from the labeling ol pesti-
 cide  product* (or whkh sale to limited
 to physician*, veterinarian*,  or  drug-
 •tot*, provided that:
   (/) The label clearly stale* that the
 product to  (or u*e only by phyiklan*
 or veterinarian*;
   (2) The  Administrator   determine*
 that such  direction* are not neceaaary
 to  prevent  unreasonable  adv*r»e  el-
 (ect* on man or the environment; and
   (J) The product to al*o a drug and
 regulated  under the provtoton* o( the
 Federal Food. Drug and Cocmelk Act,
   (C) Detailed direction* (or us* may
  be omitted from the labeling  of pe*U-
  clde product* which are Intended  (or
  uae  only by  formulalor* In preparing
  pealklde*  for sale to the public, pro-
  vided that:
    (II  There  U   Information  readily
  available  to the  formulalor* on the
  composition, toxklty. method* of us*.
  applicable restriction*  or  limitation*.
  and elfectlvervefl* of  the product for
  pe*lklde purpowe*:
    (J) The  label clearly itate* that the
   product t* Intended  for  uae only  In
   manufacturing,  formulating, mixing.
   or repacking for u*e a* i pe*lklde and
   specifies the lypeis) of pealklde prod
  •ucU Involved;
    (J) The  producl as finally manufac-
   tured,  formulated,  mixed,  or repack-
   aged U registered; and
    n a* prescribed In KMtMJ) Immedi-
ately under the  heading -Direction*
lor Use."
  (M)  Immediately  below  the  lUte-
me/il of  uae  clarification,  the slale-
ment "Jt  to a violation of Federal law
to u«e thto product In a manner Incon-
ttolenl with It* labeling."
  (Ill) The slleXs) of applkallon. aa for
eiample  the  crop*, animal*, area*, or
ob >ect* to b« treated.
  (Iv) The target  pesUi>  asaodaled
with each alU.
  (v> Th* doMge rate associated with
each alte and p«aL
  (vl) The  method of applkallon. In-
cluding Instruction*  (or dilution. If re-
quired, and lype<») of application ap-
 paralu* or equipment required.
   (vll> The frequency and timing of ap-
 plkaUon* ntcmsry to obtain effective
 reaull* without caualng unreasonable
 adverse effect* on the environment.
   (vlll) Spedfk limitation* on reentry
 to area*  where  the poitklde ha* been
 applied,   meeting  the   requirement*
 concerning  reentry  provided  by  40
 CFK Part 110.
   (Ix)  Spedfk  direction*  concerning
 the  storage and disposal of the peatl-
 cldn and IU container, meeting the re-
 quirement* of 40 CFR Part  145. These
 IrwtrucUon*  shall  be  grouped   and
 appear  under   the  heading "Storage
 and DUpoaal."  Thto heading must be
 •et In type of the same minimum slu*
 as required for the child hazard warn-
 ing (See Table In | l«l ICHhK I Xl») >
   (x) Any HcnlUUonj or rcntrktlons on
  u*e requlrec to prevent unreasonable
  advera* effects, such a*:
   (A)  Required  Intervals between ap-
  plication and  harvest of food  or  feed
  crop*.
   (B) Rotational crop realrktlons.
   (C)  Warnings a* required agalrut use
  on  certain crop*, animals,  objects, or
  In or adjacent to certain areut.
    (D) IReaerved)
    (E) For renlrkted  u»e ptallcldes. a
  statement that the pollclde  may b«
  applied  under the direct supervision of
  • certified applicator who la nol phys-
  ically present  al Ihe slle of  application
 but  nonrlheleaa   available  to  Ihe
 person applying, the  pesllclde.  unless
 the Agency has determined thai the
 prallclde may only be  applied  under
 Ihe direct supervlnlon of a certified »p
 plkalor who U physically presrnl.
  (F)  Other  pertinent  Information
 which  Ihe  Admlnlnlralor  determine]
 to  be  necenoary  for the protection ol
 man and Ihe environment.
  (j) Slalrment of Vie  Clau(/icatto»
 Dy October 23. 1919. all peallrlde prod
 ucU mu.nl bear on their labels a iilale-
 menl of lute clamlflcallon as dencrlbed
 In paragraphs (JM 1 > and (3) of thU nee-
 lion. Any pontlclde prodiicl  for which
 some ujien are clamlfled for general line
 and othem  for renlrlcted line nhall be
 separately labeled according In the l«
 bclln*  nlan<1ardi  ael forth  In IhM mib-
 iiectlon. Hnd iihall be narkelcd an ivrpn
 rale products with d fferenl reglnlra-
 lion numtxm.  one b>-arlng  directions
 only for general  usei.i) aixl  the other
 bearing dlrecllon* (or r en trie ted IIMS*)
 except Ihftt. If a  product has both re-
 ilrlcled lined) and general uneis). both
 of lhe*r unes may appear on a producl
 labeled lor  rm Irk ted une.  Such prod
 ucUi nh»ll be subjecl to Ihe provUlons
 of | 183 10(jX3>.
  (I) OenrraJ Ult ClattUlcalion. Prsll-
 clde products  bearlnn  directions for
 iwr<*)  elftA.ilfled  general iihall be  la-
 beled with the exact words  "General
 Climllkatlon" Immediately below the
 heading "Direction* for Use." And ref-
 erence  to  the general  cliuulf(cation
 that suggests or Implies  that Ihe gen-
 eral ullllly  of  the  pesticide extends
 beyond thane  purpose* and ujies con-
 tained  In the Direction* for Us^ will be
considered a false or misleading slale-
menl under the statutory  definitions
of mlnhrnndlng.
  (3)  Iteilricted  Uir  Cl. and appear
Ing  with nufflclenl prominence relative
to other text and graphic material on
                                                                   5 161.
 the fronl panel In make It unllk<
 be overlooked under ciwlomary i    t
 (Ions  of purchase and use. Ihe
 menl  '•Restricted Use Pesticide"
 appesr.
    Directly below Ihln nUteme
 the front panel, a nummary ntnlr
 of the terms  of restriction linnoi
 a  precondition to  rcjlnlrallon
 spprar. If use ls restricted lo  cer
 applicators. Die following nisi cm.
 required:  "For retail sale lo  am
 only by Certified Appllcalmn i>r
 sons under their direct siiporvhloi
 only for Ihone uaen covered by Uir
 titled  Applicator's  cerllflcallon
 however, other rcgulaUuy reslrlcllor
 are  Imponed.  the Administrator  wl
 define the appropriate wording for
 lerms of reslrlcllon by regulation.
  (k> Advcrllslng. inciwrvedl

 (40 FTt MM*.  July  I. 1*11: 40 m
 AIH  i. ins. 40 rn wit. AU« 11. t
 amended at 41 TO I7SS. ITb • IS7SI

 I Pfl II  Criteria for «V(rrmlf.alUnXI)  of tftc   Act. or
                lo hohl a hearing U
                     no  renislrallor
                    fr  dented, as ap
                    sued, upon a de
                   Vdmlntatralor Ilial
                   pr exceeds any o
                    el forth  In para
                     (Ion. Upon suet
notice of  Inte
determine  wh
should be cance
proprlale. shall   ^
termination by the
the pesticide met
the criteria  for B/ak
graph (aX3) of kfils
determination^'   the \Admlnlntrato.
shall Issue notice  by certified mall to
the sppllca.ryl or  reglslrarX as the cax«t
may be. ktnlng  that (he  Vi>pllcanl or
reentrant/has  Ihe  oppoWunlly  to
submit b*ldence  In  rehulla\ of  niicli
presumpdon In accordance wVli para
graph (4x4) of this section ThV appl).
cant or registrant shall have  forty live
(48) /lays frorn the dale such no)irr la
senlr lo submit evidence In rebutlaj nf
lh/ prenumpllon;  provided.
     for good cause shown the Adm.,
 itralor may grant an additional nl«!

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                                PEST/DIS-1

              PESTICIDE  DISPOSAL INSTRUCTIONS

 The laoel of  ail  products, except those intended solely for domestic
 use,  must bear explicit instructions about pesticide disposal.  The
 statements listed below contain the exact wording that must appear on
 the laoel :>r  these products:

 1.  -The laoels of  all products, except domestic use, must contain the
 statement,  "Do not contaminate water, food, or feed by storage or disposal.

 2.  Except  those  products  intended solely for domestic use, the labels
 of  all  products that contain active ingredients that are Acute Hazardous
 Wastes  or are  assigned  to Toxicity Category I on the basis of oral or
 dermal  toxicity,  or Toxicity Category I or II on the basis of acute
 inhalation  toxicity must bear the following pesticide disposal statement:

    "Pesticide wastes are acutely hazardous.  Improper disposal of
    excess  pesticide, spray mixture, or rinsate is a violation of Federal
    Law.   If  these wastes cannot be disposed of by use according to
    label  instructions, contact your State Pesticide or Environmental
    Control Agency, or  the Hazardous Waste representative at  the nearest
    EPA Regional Office for guidance."

 3.  The labels  of  all products, except those intended for domestic 'use,
 containing active  or inert ingredients that are Toxic Hazardous Wastes
 or  meet any of  the criteria in 40 CFR 261, Subpart C for a hazardous.
 waste must bear the following pesticide disposal statement:

    "Pesticide  wastes are toxic.  Improper disposal of excess pesticide,
    spray mixture,  or rinsate is a violation of Federal Law.  If these
    wastes cannot  be disposed of by use according to label  instructions,
    contact your State  Pesticide or Environmental Control Agency, or  the
    Hazardous Waste representative at the nearest EPA Regional Office
    for guidance."

 4.  Labels for  all other products, except those intended for  domestic
use, must bear  the  following pesticide disposal statement:

    "Wastes resulting from the use of this product may be disposed  of on
    site or at  an  approved waste disposal facility."

5.  Products intended for domestic use only must bear  the  following
disposal statement:  "Securely wrap original container  in  several layers
of newspaper and discard in trash."
                                     100

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                                  PEST/DIS-2
         PESTICIDE ACTIVE INGREDIENTS THAT ARE ACUTE  HAZARDOUS WASTES

     PESTICIDES ON THE "E" LIST  (with RCRA »  and  CAS  »
          40 CFR 261 .33(e)

 Ac role in
 Aldicarb
 Aid r i n
 Allyl  alcohol
 Aluminum phosphide
 4-Aminopyridine  (Avitrol)
 Arsenic  ac id
 Arsenic  pentoxide
 Arsenic  trioxide
 Calcium  cyanide
 Carbon disulfide
 p-Chloroani1i ne
 Cyanides (soluble  cyanide  salts
    not otherwise specified)
 Cyanogen chloride
 Dieldrin
 O,O-Diethyl S-(2-ethylthio) ethyl]
    phosphorodith loate  (disulfoton)
 O,0-Diethyl O-pyrazinyl
    phosphorothioate   (Zinophos®)
 Dimethoa te
 0,0-Dimethyl 0-p-nitropheny1
    phosphorothioate (methyl parathion)
 4,6-Dinitro-o-cresol  and  salts
 4,6-Dinitro-o-cyclohexylphenol
 Dinoseb
 Endosu1 fan
 Endothall
 Endrin
 Famphur
 Fluoroace tarn ide
 Heptachlor
 Hexachlorohexahydro-exo,exo-
   dimethanonaphthalene  (Isodrin)
 Hydrocyanic  acid
Me thorny 1
alpha-Naphthylthiourea  (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide
   (OMPA, schradan)
Parath ion
PhenyImer
Phora te
Potass ium
Propargy1
            ric  acetate  (PMA)
          cyan ide
          alcohol
Sodium azide
Sodium cyanide
Sodium £ luoroacetat,e
                                        P003
                                        P070
                                        P004
                                        POOS
                                        P006
                                        POOS
                                        P010
                                        P011
                                        P012
                                        P021
                                        P022
                                        P024
                                        P030

                                        P031
                                        P037
                                        P039

                                        P040
107-13-1
116-06-3
309-00-2
107-18-6
1302-45-0
504-24-5
7778-39-4-.
1303-23-2
1327-53-3
592-01-8
75-15-0
106-47-8
506-77-4
60-57-1
298-04-4

297-97-2
P044
P071
P047
P034
P020
P050
P088
P051
P097
P057
P059
P069
P063
P066
P072
P075
P085
P089
P092
P094
P098
P102
P105
P106
P058
60-51-5
298-00-0
534-52-1
131-89-5
88-85-7
115-29-7
129-67-9
72-20-8
52-85-7
640-19-7
76-48-8
465-73-6
74-90-8
16752-77-5
86-88-41
54-11-5
152-16-9
56-38-2
62-38-4
298-02-2
151-50-8
107-19-7
26628-22-8
143-33-9
62-74-8
                                       01

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                                 PEST/DIS-3
 Strychnine  and  salts                   P108

 0,0,0,0-Tetraethyl                     P109
    dithiopyrophosphate  (sultotepp)
 Tetraethyl  pyrophosphate             .  Pill
 Thallium  sultate                       P115
 ThioEanox                              P045
 Toxaphene                              P123
 Warfarin  (>0.3%)                       P001
 Zinc phosphide  (>10%)                  P122
                        57-24-9
                        60-41-3
                        3689-24-5

                        107-49-3
                        7446-18-6
                        39196-18-4
                        8001-35-2
                        81-81-2
                        1314-84-7
 50 ACTIVES
 II.   PESTICIDES  DERIVED
      [40 CFR  261.31]
FROM TRI-,  TETRA-,  AND PENTACHLOROPHENOLS
 2-Chloroethyl  2-(2,4,6-trichloro-
   phenoxy) ethyl ether
 Dehydroabietylammon iura
   pentachlorophenoxide
 Erbon
 0-ethyl 0-.( 2,4,5-trichlorophenyl)
   ethylphosphonothioate
 2,2'-Methylenebis
   (3,4,6-trichlorophenol )
   (Hexachlorophene)
   --Potassium salt ot
   --Sodium salt of
   --Disodium  salt ot

 Pentachlorophenol
   --Potassium salt of
   --Sodium salt of
   --Z inc salt of
   --Zinc salt of N-alkyl
     (C16~C18)~!'3-propaned iamine
   --Pentachlorophenyl laurate

Potassium trichlorophenate (2,4,6)
Potassium trichlorophenate (2,4,5)
S i Ivex
   --2-Butoxyethy1 ester
   --Butoxypolypropoxypropy1 ester
   --Butoxypropy1 ester
   --C i •>thanolamine salt
   --^i isopropanolamine salt
   --Dimethylamine salt
   --Dipropylene glycol isobutyl
     ether ester
   --Ethanolamine salt
   --2-Ethylhexy1 ester
   - - Isoocty1 ester
               F027     5324-22-1

               F027     35109-57-0

               F027     136-25-4

               F027     327-98-0
               F027     70-30-4
               F027     67923-62-0
               F027    • 3247-34-5
               F027     5736-15-2

               F027     87-86-5
               F027     7778-73-6
               F027     131-52-2
               F027     2917-32-0
               F027

               F027     3772-94-9

               F027     2591-21-1
               F027     35471-43-3
               F027     93-72-1
               F027     19398-13-1
               F027     53404-07-2
               F027     25537-26-2
               F027     51170-59-3
               F027     53404-09-4
               F027     55617-85-1
               F027     53535-26-5

               F027     7374-47-2
               F027     53404-76-5
               F027     53404-14-1
                                     102

-------
                                 PEST/DIS-4
    --I sopropanolamine salt
    --Monohydroxylaluminum salt
    --Polypropoxypropy1 ester
    — Potassium salt
    --Propylene glycol isobutyl
       ether ester
    — Sodium salt
    — Triethanolamine salt
    --Triethy lamine salt
    --Triisopropanolamine salt
    --Tripropylene glycol isobutyl
     ether ester

Sodium 2- (2,4,5-trichlorophenoxy)
   ethyl sulfate

Tetrachlorophenols
   --A1kylamine*amine salt (as in
     fatty  acids of coconut oil)
   --Potassium salt
   --Sodlum salt

2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
2,4,5-Trichlorophenol salt of
   2,6-bis[(dimethylamino)methyl)
   eyelohexanone
2 , 4 , 5-Trichlorophenol,  sodium salt
2 , 4 , 6-Trichlorophenol,  sodium salt

2,4 , 5-Tnchlorophenoxyacetic acid
   --Alkyl  C-12 amine salt
   --Alkyl  C-13 amine salt
   --Alkyl  C-14 amine salt
   --N , N-diethylethanolamine salt
   --Dime thylamine salt
   --N,N-dimethyllinoLeylamine salt
   --N,N-dimethyloleylamine salt
   --N-oleyl-l,3-propylene
     diamine  salt
   --Sodium salt
   --Triethanolamine salt
   --Trlethylamine salt
   --Alkyl  (C3H7  - C7H9)  ester
   --Amyl ester
   --Butoxyethoxypropyl ester
   --2-Butoxyethy1 ester
   --Butoxypropy1  ester
   --Butyl  ester
   --Dipropylene  glycol isobutyl
    ether  ester
   --2-EthyIhexy1  ester
   --1sobu ty 1  esteo
F027     53404-13-0
F027     69622-82-8
F027     83562-66-7
F027     2818-16-8
F027     53466-84-5

F027     37913-89-6
F027     17369-89-0
F027     53404-74-3
F027     53404-75-4
F027     53535-30-1
F027     3570-61-4
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
25167-83-3

53535-27-6
25567-55-9
95-95-4
88-06-2
53404-83-4
136-32-3
3784-03-0
93-79-8
53404-84-5
53404-85-6
53535-37-8
53404-86-7
6369-97-7
53404-88-9
53404-89-0
53404-87-8
13560-99-1
3813-14-7
2008-46-0

120-39-8
1928-58-1
2545-59-7
1928-48-9
93-79-8
53535-31-2
1928-47-8
4938-72-1
                                    103

-------
                                 PEST/DIS-5
   — Isopropyl ester                   F027     93-78-7
   --Propylene glycol isobutyl         F027     53466-86-7
     e ther ester
   --Tripropylene glycol isobutyl      F027     53535-32-3
     e ther es ter

4-(2,4,5-Trichlorophenoxy)butyric      F027     93-80-1
   acid   [2,4,5-TB~]

2-(2 , 4,5-Trichlorophenoxy)ethyl        F027     69633-04-1
   hydrogen sulfate   [2,4,5-TES]

1,4' ,5'-Trichloro-2'-(2,4,5-           F027     69462-14-2
   trichlorophenoxy)
   methanesulfonani1ide   [Edolan  U]
                                    104

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                                 PEST/DIS-6


                   PESTICIDES THAT ARE TOXIC HAZARDOUS WASTES

 PESTICIDES ON THE "F" LIST    (with  RCRA |,  and   CAS »
    [40 CFR 261 .33( f) ]

 Acetone                               U002       67-64-1
 Aery Ion i tri le*                        U009       107-13-1
 Amitrole                              U011       61-82-5
 Benzene*                              U019       71-43-2
 Bis(2-ethyIhexyl)phthalate            U028       117-81-7
 Cacodylic acid                        U136       75-60-5
 Carbon tetrachloride*                  U211       56-23-5
 Chloral (hydrate)                      U034       302-17-0
    (chloroacetaldehyde)
 Chlordane,  technical*                  U036       57-74-9
 Chlorobenzene*                        U037       108-90-7
 4-Chloro-m-cresol                      U039       59-50-7
 Chloroform-                            U044       67-66-3
 o-Chlorophenol                        U048       95-57-8
 Creosote                              U051       8021-39-4
 Cresylic acid (cresols)*              1)052       1319-77-3
 Cyclohexane                            U056       110-82-7
 Cyc-lohexanone                         U057       108-94-1
 Decachlorooctahydro-1,3,4-metheno-    U142       143-50-0
    2H-cyclobuta[c,d]-pentalen-2-one
    (Kepone,  chlordecone)
 1,2-Dibromo-3-chloropropane  (DBCP)    U066       96-12-8
 Dibutyl  phthalate                      U069       84-74-2
 S-2,3-(Dichloroallyl  diisopropyl-     U062       2303-16-4
    thiocarbamate)  (dia 1 late,Avadex)
 o-Dichlorobenzene*                     U070       95-50-1
 p-Dichlorobenzene*                     U072      106-46-7
 DichlorodiE luoromethane                U075      75-71-8
    (Freon  12«)
 3,5-Dichloro-N-(1,1-dimethy1-2-        U192      23950-58-5
    propynyl)  benzamide
    (pronamide, Kerb*)
 Dichloro diphenyl dichloroethane      U060      72-54-8
    ( ODD)
 Dichloro diphenyl trichloroethane     U061      50-29-3
    ( DDT)
 Dichloroethyl  ether                    U025      1191-17-9
 2,4-Dichlorophenoxyacetic,             U240      94-75-7
   salts and  esters (2,4-D)*
 1,2-Dichloropropane                    U083      8003-19-8
 1,3-Dichloropropene (Telone)           U084      542-75-6
 Dimethyl phthalate                     U102      131- 1-3
Epichlorohydrin                        U041      106-89-8
   ( l-chloro-2,3-epoxypropane)
Ethyl acetate                          U112      141-78-6
Ethyl 4,4'-dichlorobenzilate           U038      510-15-6
   (chlorobenzi late )
*Proposed tor deletion  by  TCLP proposal


                            105

-------
                                 PEST/DIS-7
 Ethylene dibromide (EDB)
 Ethylene dichloride*
 Ethylene oxide
 Formaldehyde
 Furtural
 Hexachlorobenzene*
 Hexachlorocyclopentadiene
 Hexachloroetnane*
 Hydrofluoric acid
 Isobutyl alcohol*
 Lead acetate
 Lindane *
 Maleic hydrazide
 Mercury
 Methoxychlor *
 Methyl alcohol  (methanol)
 Methyl bromide
 Methyl chloride
 2,2'-Methylenebis
    ( 3,4,6-trichlorophenol )
    (hexachlorophene)
    [acute waste per  261.31]
 Methylene chloride*
 Methyl ethyl ketone*
 4-Methyl-2-pentanone
    (methyl  isobutyl  ketone)
 Naphthalene
 Nitrobenzene*
 p-Nitrophenol
 Pentachloroethane
 Pentachloronitrobenzene  (PCNB)
 Pentachlorophenol*
    (acute waste per  261.31]
 Phenol *
 Pyr id i ne *
 Resorcinol
 Safrole
 Selenium  disulfide
 Silvex   (acute waste  per  261.31]
 1,1,2,2-Tetrachloroethane*
 Tetrachloroethylene*
 2, 3,4,6-Tetrachloroptienol*
    [acute waste per  261.31]
Thiram
Toluene *
 1 , 1 , 1-Trichioroethane*
    (methyl chloroform)
Trichloroethylene*
Tr ichloromonofluoromethane
    (Freon 11«)
2 , 4 , 5-Trichlorophenol*
    [acute waste per  261.31]
2,4,6-Tnchlorophenol*
    [acute waste per  261.31]
U067
U077
U115
U122
U125
U127
U130
U131
U134
U140
U144
U129
U148
U151
U247
U154
U029
U045
U132
106-93-4
107-06-2
75-21-8
50-00-0
98-01-1
1 18-74-1
77-47-4
67-72-1
7664-39-3
78-83-1
301-04-2
58-89-9
123-33-1
7439-97-6
72-43-5
67-56-1
74-83-9
74-87-3
70-30-4
U080
U159
U161
U165
U169
U170
U184
U185
U242
U188
U196
U201
U203
U205
U233
U209
U210
U212
U244
U220
U226
U228
U121
U230
U231
75-09-2
78-93-3
108-10-1
91-20-3.
98-95-3
100-02-7
76-01-7
82-68-8
87-86-5
108-95-2
110-86-1
108-46-3
94-59-7
7488-56-4
93-72-1
79-34-5
127-18-4

137-26-8
108-88-3
71-55-6
79-01-6
75-69-4
95-95-4
88-06-2
                                    106

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                                PEST/DIS-8


2,4,5-Trichlorophenoxyacetic acid     U232      93-76-5
    (2,4,5-T)*
    [acute waste per  261.31]
Wartarin  «0.3%)                      U248      81-81-2
X/lene                                U239      1330-20-7
Zinc pnospliide  <<10%)                 U249      1314-84-7


83 ACTIVES
                                107

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                          CONT/DIS-1

               CONTAINER DISPOSAL INSTRUCTIONS

    The laoel ot each product must bear container disposal
instrjrtions appropriate to the type of container.

    1.  Ocmestic use products must oear one ot tne following
container •:: :. soosa L statements:
Container Type
                                Statement
 Non-aerosol products
 (bottles, c'ans, jars)
                Do not reuse container  (bottle, can, jar).
                Rinse thoroughly before discarding  in trash.
 Non-aerosol products
  bags
              I
Do not reuse bag.  Discard bag in trash.
 Aerosol products
                Replace cap and discard containers  in
                trash.   3o not incinerate or puncture.
    2.
based on
All other products must bear container disposal  instructions,
 container type, listed below:
 Container Type
                                 Statement
Metal
conta i ners
( non-aerosol )
Plastic containers
Glass containers
Fiber drums
with liners
Paper and
plastic bags
Compressed gas
cy 1 inders
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
author 1 1 les .
Triple rinse (or equivalent). Then otter
nor recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay out of smoke. 1
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reused^-, dispose of in the same manner.
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Return empty cylinder for reuse (or
similar wording) _
     Manufacturer may replace  this  phrase with one indicating
     whether and h'ow tiber drum  may  be  reused.
                                108

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                           PHYS/CHEM-1
                    PHYSICAL/CHEMICAL HAZARDS

Criteria                              R_equired Label Statement

I.  Pressurized Containers
        F 1 a s n p o i n t at ~>~ below
        2 J ° F ;  or it there  is a
        t 1 a s n o a c '< at any valve
        opening.
        Flashpoint above 20°F
        and not over 80°F; or
        if the flame extension
        is more than 13 inches
        long at a distance of
        6 inches f rom the
        va ive opening.

        All Other Pressurized
        Containers
II.   Non-Pressurized Containers

    A.   Flashpoint at or below
        20°F.
    B.   Flashpoint above  20°F
        and not over 80°F.

    C.   Flashpoint over 80°F
        and not over 150°F.

    D.   Flashpoint above
        150°F.
Extremely flammaole.
Contents under pressure.
Keep away trom tire,  spares,
and heated surfaces.   Do not"
puncture or incinerate
container.  Exposure to
temperatures above L3'J°F
may cause bursting.

Flammable.  Contents under
pressure.  Keep away from
heat, sparks, and flame.  Do
not puncture or incinerate
container.  Exposure to
temperatures above 130°F
may cause bursting.

Contents under pressure.
Do  not  use or  -ore near
heat or open t^ame.  Do not
puncture or  incinerate
container.  Exposure to
temperatures above  13U°F
may cause bursting.
Extremely  flammable.   Keep
away  from  fire,  sparks,  and
heated  surfaces.

Flammable.   Keep away from
heat  and open  flame.

Do not  use or  store near
heat  and open  flame.

None  requ i red•
                          109

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                             STOR-1

              STORAGE  INSTRUCTIONS FOR  PESTICIDES

 Heading:

 All products  are  required  to Dear specific  laoel  instructions
 about storace and disposal.   Storage and disposal  instructions
 rrust be jped togetner  in  the air-ect ions  cor use portion ot
 the laoel  under the heading  STORAGE AND DISPOSAL.  Products
 intended solely tor domestic use need  not include  the heading
 "STORAGE AND  DISPOSAL."

 Storage Instructions:

 All product labels are required to have appropriate storage
 instructions.  Specific storage instructions are  not prescribed.
 Each registrant must develop  his own storage instructions,
 considering,  when applicable,  the following factors:

 1.   Conditions of  storage  that might alter  the composition or
     usefulness of  the pesticide.  Examples  could  be temperature
     extremes, excessive moisture or humidity, heat, sunlight,
     tricticr, or  contaminating substances or media.

 2.   Physical  requirements of  storage which might  adversely
     affect the container of  the product and  its ability to
     continue  to function properly.  Requirements  might include
     positioning of the container in storage, storage or damage
     due to stacking, penetration of moisture, and  ability to
     withstand shock or friction.

 3.   Specifications for handling the pesticide container,
     including movement of container within  the storage area,
     proper opening and closing procedures (particularly for
     opened containers), and  measures to minimize  exposure
     wnile opening or closing  container.

4.   Instructions-on what to  do if the  container  is damaged  in
     any way,  or if the pesticide is leaking or has been.
     spilled,  and precautions  to minimize exposure if damage  occurs.

5.  General precautions concerning locked storage, storage-in
    original container only,  and separation of pesticides
    during storage to prevent cross-contamination of other
    pesticides, fertilizer,  food, and  teed.

6.  General storage instructions for household products  should
    enphasize storage in original container and  placement in
     locked storage areas.
                                  1 10

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   APPENDIX  III
USE INDEX APPENDIX
        }  \ 1

-------
                   Compete i urn of Pcceatanle u

                             OXfiMYu

                       TQ5LE PC" CONTENDS

 Site Name	.	Dace

 TE3=ES~RIALFOCDCRQ2                                            i
  ' HQ r i C'_i 1 t ura 1  Crops >                                            i
 "ERREE""5 13'-  NON-ODD  CROP                                        il
  ( Pgr i cu 1 t ura 1  Crops )                                           c. I
 5REENHOUSE FOOD CROP                                            i7
  (Agricultural  Crops)                                           c.7
 GREENHOUSE NONFOOD DROP                                         18
  (Ornamental  Plants  and Forest Trees)                          cS
     e                                                             £,  c!7
ftpole ( rionbear i ng )                                                3
Cantaloupe                                                        ^
Cat'rots                                                            H
Celery                                                            5
Cherry                                                           £7
Cher^ry (ncndearing)                                               £,
Citrus Fruits                                                     7,  S7
Citrus Fruits  (nonbearing)                                       8
Cotton                                                            8
Cucumber                                                          4
Eggp1 ant                                                          3
Gar 1 ic                                                            10
Ginger                                                            1 1
Honeydew Melons                                                    *+
Onion                                                             11
Ornamental Plants                                                £4,  c8
Ornamental Plants (interior plantscapes)                       30
Peacn                                                             d7
Peach (nonbearing)                                                13
Peanuts                                                            13
Pear                                                               14,  27
Pear  (nondearing)                                                15
Pepper (bell  peppers)                                            15
Peppermint                                                        1&
Pineapp1e                                                         17
Plum                                                               £7
Plum  (nonbearing)                                                17
Potato                                                            18
Soybeans                                                          13
Spearmint                                                         16
Squash                                                              4
Strawberry                                                        £0, c.1
Sweet  Potato                                                      £0
Tobacco                                                            23
Tomato                                                            21
Watermelons                                                        4
Issued:   £-06-86        III-103801-i          1  12
Provisional Update:   5-11-87

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                              CC'mcena. i urn of  ^cceota'Dle Uses

103QO1                                  OXPMYL

          TYPE  PEST ICIDE :    Nematicide,   Insecticide,  Pcancide

          FQRnULQTIONS:
          ^ I     ' ^ E' •'. )
          G     i 1 '.'% )
          'il /' '_  '2 1  ti / g a i ;

          GENE ~^i__ ?~~~, '. '.35  M.Np _lriTMTICNS:   Oxamyl ls  a  RESTRICTED USE  PES'l-
          <_IDE  C'..e  to ac^te  toxicity  ana  toxicity  to birds ana  mammals.   «p-
          ply ei trier-  f.; r-rnu 1 at i on only in  cornrnerc i a 1 and  farm plantings;  do
          not  use  in home  plantings.   Do  not apply in Suffolk  and Nassau
          Counties,  Long  Island,  NY,  except   (Reg.  No.  3O4-415,  1O% G)  for- con-
          tainer  grown  nursery stock,  greenhouse,  and  interior  plantscapes.
          Do  not  enter-  treated areas  for-  i^  hours  after  application  unless  ap-
          propriate  protective clothing  is  worn.
          Uhen  mixing spray,  loading,  applying,  or otherwise handling,  wear
          protective clothing,  goggles,   and  an  approved  mask or respirator.
          The  use  of the  2  pound per  gallon  formulation  in greerihouses  is
          limited  to SLN-FL770G44 and SLN-OH7SOOO1 .   The  operator must  wear- a
          suitable full-faced  mask  and  the  greenhouse must be  ventilated for
          1 hour  after-  treatment.
          Oxamyl  is  tc>xic  to wildlife.    Cover,  collect,  or incorporate  gran-
          ules  spilled on  soil  surfaces.
          Do  not  plan crops other than  those with  registered oxamyl  uses
          within  6 months  after- the  last  application.
          During  aerial  application,  human  flaggers are prohibited  unless  in
          totally  enclosed vehicle.
          Bee  Cantion;
          The  2 pound per  gallon formulation  is highly  toxic  to bees exposed
          to direct  treatment  or residues on blooming  crops or weed's.   Do  not
          apply oxamyl or  allow to  drift  to  blooming crops or  weeds  if bees
          are  visit i rig the treatment  area.
         Ground Uiater Qdvisory;   Residues  of  oxamyl can seep  or  leach
          through  soil and can contaminate  ground  water which  may  be used  for
         drinking.   Users are advised  not  to  apply oxamyl where  the water-
         table is close to the surface  and  where  soils are very  permeable,
          i.e.,  well-drained soils  such  as  loamy sands.   Your  local  Rgricul-
         tur-al  Soil Conservation Service can  provide  information  on the  soil
          types  in your- area and the  location  of the  ground water.
         Dosage rates are given in  active  ingredient.
         agricultural Crop Tolerances  (other-  than those  listed  in the  text) :
         Banana ,      0.3 ppm
         P'.impk  in       2. 0 pprn
         Definition of Terms;
         SLN  -  Special Local  Needs
         Claims for pest  control  limited to  suppression  of  population  are
         indicated  by an  entirely  parenthesized  pest  name.
         Issued:   £-06-86         I I I- 103801 - 1
         Provisional  Update:   5-11-87                 i  i 7

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               EPP Cc'ivipenc i urn of  ncceotaole  uses

                               GXfiriYi_
5 i te and  Pest
Dosages  ana    : o 1 e-ance.  ^se,
Forriiu 1 ationis'
                    i f.i i t a t i c r s
               ••I-or C-OP
                                        1 H  aay  pr-enar-vesr  ir.ter-vai
                                        tnr-O'.ign  c:.O  DO'-inas  oer  acr-e.
                                        DC  not  graze  livesrc'CK  i r, t^
                                        or-cnaras.
                                        DC  net  acDDly  at  Die cm or-  w 11 - i r.
                                        20  days  after- bio on:,  or fr-r.ur
                                        tniriniriD may  occur.
                                        Do  not  apply  were  tnan  400  g          apply at  pink   (no  petals openea)
                 when aphids  are present  i n  sigra-
                 f leant  nurnpers.   For apple  ap^ic.
                 apoly when 50   percent  or- more or
                 the  terminals   are   infested  witn
                 a 3 - i d s.
I ssued:    2-06-86
    I I 1-103801-1
                                                   1 14

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                      CornDend i urn of ftcceota^e  _,ses

                                  CXPMYL
 Site  ar,d
                          Dosages a rig    ~o1erance.  Use,  i_ i M 1t a t i •:•
                          For mu 1 a t i or, ( s )
                , t ; r, uea >
                                      . o '
     Soot t eo  t erit i -
       form  1 ea f 011 ner
       ( 1arvae)
                                 g   gal
                              ib/gal
                              /L.)
             ueiavec  dormant  ana  foliar-  a-^.x-
             c a t i c- r-- s .    For- first  o r o o c  i e a ~ -
             miner   (adults ana  larvae),  a D D . ,
             at  p i ri K  (no  petals  o o e r i e c J .   f- .;• r •
             secona Qrooa  ieafnuner  (larvae;,
             apoiy  when there ar-e an  average
             of  3.  or  more  lar-vae oer  leaf  in
             the  sao-feeclirig  stage.   Ppolica-
             t i C'Ti  should  be  maae oefc't-e  tne
             lar-vae er.ter  into  the tissue —
             f e e a i n g  stage.

             SLN  -  Use  limited  to CT.
             Delayed  dormant  aria foliar-  aopli-
             catiC'ns.    For-  first brood  leaf-
             miner-   (adults aria  lar-vae),  aooiv
             at  pink  (before Bloom).    For- se-
             cond  brood  le'afminer  (lar-vae),
             apply  30 days  after- bloom if  in-
             festation  is 2  mines  per  leaf  aria
             the majority of  lar-vae  are sap-
             feeders.    Repeat  i n 2  to  ^ wee-s
              i f  neeaed .
                           CSi_NJ            SLN  - Use  limited  to NY arid Vi.
                          0.25-0.5  IP/   Delayed  dormant  arid  foliar- appii-
                            1 (.'0  gal        cations.    For  first  orooo  leaf-
                           (c:  Ib/gal       miner  (adults  ana  larvae),  apply
                            SC/L)           orice befor-e  bloom.   For secona
                                            brc'Od  leafminer   (larvae),  appiy
                                            30 days  after  bloom if infesta-
                                            tion is  1  mine per- leaf-    Repeat
                                             in 3 t c>  A  meei*s   if neeaea.
     Whit e  apple
       1ea fnoooer
                                         ft pp 1 y
                                        o f  1 e a f h o c -
 !>. c'5-0. 5  lb/   Foliar-  application.
  100  gal        significant  nurnoers
 ! i lb/c.al       pers  are present.   Repeat  at  i<.
  SC/L)           to  1A day  iritervals  as neeaec.
           ( n.:>ripear- i n c >
                                             ftpply  to  trees  that  will  not  oe
                                             fruit  within  1 c.  months  after-  ^
                                             plicatior.    Do  not  treat  oiar,Li
                                             stocK  by  root  dip.

                          Refer to TERR£5TRIfti_ NONFOOD  CROP,   (Ornament 
-------
                                                          aDie _ses
                                             OXP.MVL
                                     Dosaces
                                     Forr,".i 1 at 1 or ( s ^
                                                       'ole-'ance,  use.
                   e « - e,
                i- '.'a S'
                •   po'una  oer  acre for  fo
                                                       D 1 1 C a t ion.
                                                       Preplant  soil  a DD : i ca t i or,
                                                       A. O  pounds per acre.
!\ E TJ ~ _
                  i_ e s i o n
                   t oae =
                  Ring  n
                   CS-N-
                  Roc c-K
                   toces
                   J a v a n
                  St i nc
                  £ t '.i n t
    '- odes
     I NJ
riot  nefiia
  (exceat
ese '
                                     £.0-4.0 Ib/P
                                     (£ 1b/ga i
                                      5C/L)
                                     (1O%  G)
                                     0.5-1.0 1 b/ft
                                      i c.  1 b/ ga 1
                         ner.ia t oces
                 Ppfiics  CSi_"--irL_]
                 L i r i C' M / r a
                  fr' l r.er-s
                              1 ea f-
'.'. 5-1. «.'  1 b/ft
(1  1 b / g a i
 SC/L)
               Carrot s
I \~r.-^
                    rrot  weev i i
                                       . 5-1.0  i b/
                                      (c 1b/ga1
                 Precis nt  soil  application.   e
                 cast;  or,  for  Dana  treatment,
                 proportionately less f orrm.i i at io
                   Following  application  arrc  ce*:'
                 planting,  i ncc'r pc^ra t e f or MM i a t
                                                                  '.se
                                                       ii: to
                                                                incnes  into tne soi
                              Foliar  application.   Pooiv
                              weens after  planting  anc
                              t o>  5 weens  later.   Preferaoly, a:
                              plications  snould  be  usea  in  CJT,-
                              juriction with prep 1 ant soil aonli
                              cation.   SLN-IN:    If  soil  aoDiic;
                              tiori is no't  used,  apply  10 to It
                              days after  planting  ana  repeat 1'
                              to  £'1 days  later.

                              Foliar  application.   Pppiy wrie^
                              insects first appear  ana resea: "i
                              weekly  c>r  as needea.   Wnere  i e a f
                              ni i r.er-  i ri f es t a t i ons C'CCuir anriuai-
                              iy,  apply  cl tc>  4 weeks  after
                              olariting and reoeat  weekly or a=
                              neecea.   SLN-CA-:   P'lay also oe a;
                              piiea  by aircraft.

                              0. 1 pprn
                              ftt-plariting soil aop 1 i cat i on
                              through **.0 pou'nas per  acr~e.
                              Preplant so> i 1  application
                              B.O pc'unas per  acr~e.
                              SLN-ril:   1A pay prehar-vest
                              va 1 through  1 . < '.' pouna  per'
                              for  foliar application.
                              Do  not  apply  i n Cft.

                              5LN  —  Use  limited  to Ml.
                              Foliar application.    H vly as
                              directea  spray  in a  mi  , inv.ini  c f
                              gallons  per  acr^e.   Apply  '-ID  t1-
                              treatments  at  c:  to 2 wee-< ir.t
                              vais  beginning  wnen  i ri sects  a
                              pear  i n  sufficient  riijmaer'S  to
                              cause   injury.
            Issued:    £-06-6£
                                          I I 1-103801-4
                                                                   1  16

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                             •EPS  Compete i urn  of  Accentaole  uses

                                             G
            bite  a r, c  H e s'.
                     DC-sages  ana    To I eranee,  use,  — i rn i ^ at i ons
                     •r :•>-mu 1 a t i or. ( s >
N E •_ & A A A
Root —">'••:"  nema —
 todes  >, except
 Javanese )
Spiral  nerna-
 t o a e s
Sting  nernatoaes
St'.mt  nematoces
( c.  i D / g a i
 SC/L >
<10% G)

>i. 'J-A-. i.''  1 O / fi
i c.  i D/ ga 1
 SC/L)
( 1 ll'Vi l3 ^
                                      CSLNJ
                                      1.1-1.5  or/
                                       1, GOO  ft  of
                                       row
                                       L 6  in.
                                       width]
                                      (10* G)
      ,=> r.t  SC' i i  a D o i i c a t i on .    f--o re-
cast.   ftpDiy  to tne soil  i ri  a Min-
imum of cX> gallons  per- acre  w i T: n -
in  1 weeK  of  oiantinn.    IricoroC'r-
ate  to a  aeotn of  i t •:• t,  ir.cnes.

Ht-olanting  sc>il  aoolication.
I n —furrow.    Pooiy  in  the  seea f'.ir-
rc'w  during tne planting  opera-
tion,   ftpoly  the  soluole  concen-
trate  f or^mu 1 at i on  in  a minimum of
c:1!'  gallc>ns per- acre.

Sl_N  -  Use  limited  to  MI.
Pt-planting  soil  application.   fto-
ply  C'ver-  tne planting area  -arid  in-
corporate thorouahiy.
              Le .
                          weev i 1
                                       . 0  1 b / «
                                      (1  Ib/ga 1
                                       SC/L)
                                       ^.U  ppm
                                       1A  day  preharvest  interval
                                       through  1 .'!>  pound  per acre  for
                                       foliar  application  in F L ,  MI,  o r
                                       PP.
                                       SLN-rL  (trimmed  celery):  5 oay
                                       preharvest   interval  through 0.5
                                       pound  per- acre or  7  day  orehar-
                                       vest  interval  through  1.0  pouno
                                       per acre  for foliar  application.
                                       SLN-MI:   Preplant  soil  applica-
                                       tion  through 6.0 pounds per-  acre.

                                       SLN -  Use  limited to  MI.
                                       Foliar-'application.    Apply  3
                                       times  at  £  to  3  week  intervals
                                       when  insects appear  in  signifi-
                                       cant  number's to  cause injury.
                                       May be applied  alone  or  following
                                       the preplant application.
            Issued:    £-06-86
                         I I I-103801-!
                                                                     1 17

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                            EPfl Compendium  of Acceptable  Uses

                                            DXftMYL
             Site  and  •-'est
           Dosages  and    Tolerar.ce.  Use.  Limitations
           Form i.i 1 a t ion < s i
                   t - ~ e s
                 Pin r. e-
root-knot nemat oaes.  apply **.o t
6. C' pounds  per  acre  on a  Droac-
cast basis.   Incorporate  to c.
dept!~i of 4  to £  inches.

SLN - Use limited to  M  anc --.
Preplant soil application.   r^-,:
treatment.   ftpply to  a band B  t:
1£  inches wide  on the row.   Inc
porate  to a depth of  <+ inches.

SL.N - Use  limited to  Ml anc Pfi.
Fo.iar  app 1 icat 1 or,.   Following
tie pr-eplarit soil application,
aocly 2 times at  c1  to 2 w e e K  in
tervals beginning c.1  to 2  wee- s
after t t'ansp 1 ant i ng ;  or-,  if no
pr-eplant  a pD 1 i cat i •:• n  is niace,
begin as  soon as r.ew gr-.;.w*Ti s~C'
a^ter t rarisp i ant i r. :: .
                 ber-pent i ne
                   lea f rii i ner
                   comp i ex
                   (except
                   i_ i r i C'my : a
                   t rofol 1 l J
           CSt-N]
           0. 5-1.0  1D/P
            -
                                                                                     i nf es
                             tion.
                             c r a f t .
                                                               May pe  applied  by
               I nerry  ( n c> n p e a r i r, q )
                                                       woDiy  to  trees that  wiii  r-'.
                                                       ^njit  within  li  rnor, thc^ afte'
                                                       plication.    Do not tre^~  Dl
                                                       stoc*  by  root  dip.
                                     Refer-  to TESREST^IAL  NONFOOD  CRQO,   ( Ci-r,af.i5' * <
                                     Plants  and  Forest  Trees),  Ornamental  P^ar.-.E,
                                     tC'f- use arid  limitation i r. f C'r-'^a ~ i c r, .
            Issuea:   i-06-86
               I I 1-102601-6
                                                      1 18

-------
                         Compencium of  Pcceztas^e  -ses
 Site  ar.c  ^esr           Dosages  ar.c     To 1 g--a r re,   use,
                             c or m u i a t i o r i 5 ;.
     ^T r-'.'. s  --•'•:•:=_                           -;.'.'  pprr
                                                 7  a a y  ore harvest  i r t s"-v a .   ~ ~
                                                 I.11  pour,-  cer-  acr-e  f : - -  - i  . ^ a •   r
                                                 pllcatlO"  w i	  a  r.ia » 1 r,i •  • •   ;
                                                 pi icat ions  De>--  v ea r- .
                                                 SL-N-TX :    7  day  crer-ia--v = s:   : ' - -r.
                                                 va 1  through  11!. 0  pounc. s  oe-   f :  5
                                                 per-  season  for-  foli-ar  a iro 1 i  Z;--
                                                 t i or i.
                                                 5i_N-&Z  arid  CP :    7  ca-   rv-=~f  . e _
                                                 interval  thr-ough  c..'!'  rcv-cr  z-:-•
                                                 acr-e   for"  irr-igation wat&-   a . i
                                                 cation;  aric  ao  not  apzi..Y  mere
                                                 tnan  2.0  pouncs  pe-- azr'e  i-
                                                 5'.i  aay  periC'C.
                                                 D'O  not  gr-aze  livestcz-  i r\  t--e^ ;
                                                 orcharcs.

      Citrus  riematooe  C5i_Nj              Si_N  -  Use  lirnitec  tc  T X .
                             ii. 0 - ^.  0  i P / A   Collar applicatiC'n.    O p p » y  2  T •:
                             (c  ID/gal        times  between the  new  flush  o~
                               SC/l_)             growth  in  the spring   ar.d  trie
                                                 fa 1 1 .

      (Citrus  nema-     [5i_Nj              5i_N  -  Use  limited  to   fiZ ar.c  C^.
       toae;               0.5-2.0  lp/P   Irrigation  water  application.    i
                             (i  IP/gal        piy  be metering   into   fiooa   irr;
                               SC/i_)             tion  water-  or  into  drip  ir-r'i^J-
                                                 t io n  systems.    0 p piy   ir the
                                                 soring wher,  soil  temperature   i -7
                                                                    1  19

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              EPft Cofnoenc i urn  or Acceot
                                             aaie  uses
Site  ar.g  Pest
                       Dosages  and    Tolerance.   Use,  _ i .M ; t a t
                       r or M i.i i a t i on ( s )
                          0. 0625 — O. 2
                            iD/lOO  Dci
                            I '.i D t o  *nj'
                            cai/t^J
                          (c.  Ib/gai
                            5C/i_)
                                          F.; i i a r   a 20 1 i ca r i or .    w ro ; v ^ =
                                          SO Or,  as  Sicr, iflCc-r.t   1 r, f e S t 
                                          c' *  cay preharvest  interval
                                          tnr-ougn  1 .  0  pounc  per- acr'e  f •'"'
                                          foliar application.
                                          L/C'  not grace or  feea  tr-eatec
                                          cotton to  livestock.
     Boil  weevil       0. 1 25-0.1
     Cctton flea-       ID/ft
      n.:.pr->r-             (2  lo/aal
                  plant    SC/^_)
                                          Foliar  a DP 11 cat ion.   npp^y  tsne^
                                          damaging populations  apoe^-  ^('r
                                          repeat  as  r.eedec  to  rnainte  '  c.
                                          troi.    Si_N-TX:    may  pe  acjliec,
                                          a i rcra f t i n a  m i n i rin.if.i .:• ^  2  c 
-------
                         ornpenc i urn  of  Pccestaoie
        ar.g
                           Dosages
                           i- orriiu ; a t i c r- <. s i
                                               c . er ance,  use,
                                                                        tat : or s
             < cor. r i n•. ec
                                        I p / M  - i 1 i a r-  appiicaticn.    H P p . /  ~
                                              a a '•' a c i r, c  c •:• p '.• ^ a t i " r, 5  D P c : "  t
                                              p v i 1 a .    ^ e D e a t  at  t  t •:  i  c .-  .
                                              tervais  for-  MO  t C'  *»  a D ^ • i c a t
                                              S •_ ,\ — fl Z  aria  CM:   r^a^  DE?  aDL^i
                                              air-craft .
                   See
                                                     ant a i O'.ioe  c
   c: q q
           cs
                   c.. (-•'  ODrn
                   7 day  prei ar- vest  ir.ter-vai  t n r !•
                   1 . (j  po'.ind  per  a~re w^e-'i  '.isirc
                   soil a po i i ca t i or,  witn  f c i i ar-  a
                   Ciicatiori;  or-  1  cay  p--eiarves-;
                   inter-val  tnrouci  1 . C.1  ^oanc  pi -•
                   acre for  foliar  application <: r,

O. 5-1.0  1P/P   Foliar  application.    Apply  C>-
      Coloraao  pc'tato  (£  la/gal
       beet le              SC/i_)
      l_ea f rn i ners
      r^ i t es
                   ground equipment  wneri  insect1
                   first  appear-.   Repeat  at   1  t
                   intervals as neeceo.
      Plant-parasitic soil:
       nernatoaes        ^.0  io/ft
                              or
                           f o 1 i a r- :
                           O.5  Ib/fi
                            (2  i b/ga 1
                             SC/L)
                   Use  limited  to areas  otner- tnar
                   CA.
                   Soil  ana  foliar-  appiicatic^ris.
                   p j. y  t C' the  soil  as  a  Dana  trea
                   ment  i± t c. 5  weens, after-  trans-
                   planting.    Repeat  4  weeks  late'
                   Two  to A  weeks after  the  soil
                   treatments,  make i  foliar  acpl
                   catiC'Tis  Dy  gr-ounc  eq L> i p-nent  at
                   to c:  ween  inter-va.s.
Issuea:   2-C'6-86
     I I 1-103601-
                                                          121

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                                C.PO  Cornoenc i urn  o*  Pcceotaoie  uses

                                                 GXH"1Yl_

               iice  ar.c  J e s t          Dosages  ana    To 1 erar.ce,  _se,  _ : • • . T j : : •: r •-
                                         For MM i 3 r 1 or. ( 5 ;

                                                            O. 1  por.i
                                                            5_*< —03:    1 *•  day  c^e"1 => •' - F-S •
                                                            interval,  t ~i rc".i c ~   <* . v  o :   r :
                                                            ac'-e  ^o -•  s ;• i i   a^3..ca"i_f.
                    ''.I i o  anc  stem    C5i_NJ             5i_N  -  Use  1 in:;-r.ee  to  C-*.
                    nematoae          1.5 —A. C'  IP/M   fit—planting  ar,c  DC -5- e--e •- c= - .ce
MCAM&^H          St uPby-root       ( c;  Ib/'gai       soil  app i i ca t i or s.    £• - r . >  2.''..  t:
                           ;odes          5C/i_)            A. C'  pounds  oer-  acr-e  at  pla'.t ;r,;.
                                                            as an  in —f'.irrow  pare  S3f-e,   . r,  i.
                                                            to 5'."1  gallons,  or-  a 5  an  i r, --.i ••-•.;, „
                                                            cr-eric^  using  1.5  t o  il.'!'  p.:-.. r>cs
                                                            per-  acr-e  i r,  100  tc- 15'J  cailC'rs.
                                                            fippl>  2.0  t o>  A.'.'-  p-zurics  per-  ac-'e
                                                            i r> c.1 '  to  5'.  gal lens  (Pane.  <: -
                                                            oroaccas"/  as  post emergence  tr-e^7
                                                            riients).    Mpoly  at  flag  leaf  (I :;.
                                                            3 leaf)   stage  anc  repeat  at  ;*. •:
                                                            21  aay  intervals.   Barid  widt-

                                                            oer-  acre  given  are on  a  bre^ae-ias:
                                                            oasis;  for  bana  ape 1 i ca4; i e-n !.>•: =
                                                            pr-oport i on-at e 1 y  less,.   M:^.:C?-
                                                            tioris  s no'.i la  be  f .;• i ,. e v.ec  -".-  'i'-e--
                                                            neaa  irr-igation  e^r- rair  :" =• . i <~:~-
                                                            in 2 days of  treatr.-ent   (•;i.J,t:;  t:
                                                            acre  incn).

                                         CSuNj             5i_N  -  Use  iimitea  t •: CA.
                                         1. O-ii. 0  IP/    Pr-olaritiriQ ar,c  pest-olarit  s: . 1
                                          surface  &     aooiications.   Apoly a~   plar.r.nc
                                         (cr  Ib/gal       as an  in—furrow  spray  folle^ec  o>
                                          5C/i_)             irrigation.    Ppoly  c.1  to  2  a r: i" ; •:
                                                            na 1  times,  at  1 A t o   c. 1  cay  ir;-.£--
                                                            vais.  Py  injection  into  sprin -.S1'
                                                             1 i r.es  e>r  furrow  i r-r-1 gat i :>r., or- 2>
                                                            oariped app 1 icat I'l^n   (1  to  2  inc'es
                                                            wice)  o lac eel  o>r  tne  soil  S'..r-f;, r. ?
                                                            at  t f. e base  •:• f  ': n e P . a " ': =   f e
                                                            ed  witnin  A6  ho-.ir-s a*rp--  =?•  '.-"
                                                                           1  22
              Issued:    i-0£-S£           I I I-iLoSul-10

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                               £pq  Compendium  of  ficceptaple  uses

                                                QXSMYi_

              iite  ana  Mes t          Dosages  arc     To. pi-a nee,   Lse,  - i m i ~ a t \
                                        - c •T:II.. .at i c r, ( 5 )

                !•.-=?'-                                    0. 1  pom
                                                           5_"J—'I :   3'   cav D--e~ar-ve
                                                           interval  t ~ r- o u o h  s .  '-.-  D :•'.
                                                           a c r =  f o'-  s c : i  a?"lira'i:".    ^ ~ ~ .
                                                           u n  to  7  wee-s  a f t e < •  ^ . a r t •. r 5

                                                           foi iar  apoi icat i c n.

                  &'.!••-r.;.w j. r,g  r.ema-  C S i_ N j             S i_ N -  Use  iimitec  t:  ^'. .
                    t C'de               sc' i 1 :             Prep i ant  so i i  ana /  :•'• f :•. i a •• ? - :
NtJB&HM          i_esion  nema-      c.. 'J-s. '.'>  Ib/fi   cations.   fippiy as  a pr-i^ar ca = t  •: -
                    toces                 or-              band  treatment   (using  pr :oor t : o'-
                  Poot—knot  nema-  foliar:          ateiy   less  formulation)   aefc^-e
                    toaes              0.5-1.O  Ib/P   planting.     I nco'-pc^rat e i  to ^
                  S t i r i g  r i e rn a t o ci e s  ( c:  In/cal        inches   into the s o i i .    P< p c . y
                                         £C/_)            foliar sprays  i  tc  4 wee-^s  a^ter'
                                                           plant ing ana  repeat 14 to  c. I  cays
                                                           later-    Foiiar sprays  shoalc  re
                                                           used  preferably as  a  foilow-UP to
                                                           the soil  application.   OR.  a^ply
                                                           c:.0 t C' 4.0  pc'ij^ics  per  acr-e  cirect
                                                           ly  to the  sc> i 1  by  c--;o  irr-igat:c-
                                                           emitters.    fipaly  1  wee^  a^re-'
                                                           plariting  ar.c  repeat a*:  1-  c?^ :r-
                                                           tervals  as   r.eecec.

                            r^ieion                         See Cantaloupe  cluste--.
               Or, ; •:• n                                     C'. 1  pprn
                                                           SLN-ID,  MI,  OR,  TX,  ana  ^fi:    Is
                                                           day  preharvest  interval  tnro'.icr,
                                                           O. 5  pound  per  acre  for'  foliar
                                                           application.
                                                           Do not  ha-vest  tops  c>f  tre
                                                            4. C'  pounas  per-  acre  as  an  cas*. -
                                                            fi.irrow  bar.d  spray  i r\ i'".1 to S1   c,
                                                            Ions.
                                                                          123
            Issued:    i-Ofc-86           I I I - 103601 - 1 1

-------
                      uompend i urn o f ficceotaole  uses
Site ar

   ,- - - -   < CC r, t l nuec '
                          C5_Nj            5_"- -  Use  lir.ntec  t o  M I .
                          1.1-1.3 or'    Preplan t  s •:• i i  application .   £•--.,
                           1,OOO ft  •!' f   : n  a  6 men  oati  eve-- sla'ti^a
                           row             ar~ea.   I nccr-por-ar e c "ICT-C >.•. gi-, . y .
                          ( 1 C'%  G )

                          CSuNl            SI_N -  use  iirnitec  t •:  I = .
                          1.5-^.'I>  io/ft   ftt-o.ariting  anc  PC s r e-iier- ger,c =
                          ( c.  ID/gal       soil  aop 1 i cat i ors.   Pool/ j.1.1  :;
                           SC/L.)           ^. 0 pouncs  per  ac^'e  at piar,rir,-
                                           as  an  i ri- f Lir*-C'W  oar.c  GC-~ay  i '  J.
                                           t C'  5O  gallons,  or as  an  :r>-f jr-r  -.,
                                           ar-er.ci usiric 1.5  to  c:. 0  pc-^'ici
                                           per acre  in  1 OO  to i5O cailo^i..
                                           Apply  2,O  to 4. 0  pounds  per a~-c-
                                           in  £1])  to  50  gallons   (banr or
                                           Orc'adcast )  as pC'St ernercerice tr-e^1:
                                           ments.   ftpply at   flag  leaf  (i t°:
                                           2  leaf stage)  and  reoeat at 14  t
                                           cl  day  intervals.   &and  .w i c *: -•
                                           snoold be 4  t c>  8  inches.    Gallc'
                                           per  acre given  are  on  a   Droacrc??1
                                           Pasis;  for  Band application use
                                           proport i onat e 1 y less.   Hp^.ica-
                                           tions snoi.iid  De followec  P/ eve-
                                           head   irrigation or"  rainfall *~.~~
                                            i n 5  days of  treatment  ((.'.£5 t:
                                           acr-e   i nch ) .
                                            Si_N  - Use  limited  to  CH.
                          l.'!>-c:.0  IP/     Pt -pi ant ing  arid post -pi ant soil
                           surface  ft      applications.   Ppply  at -plant ir.:;
                          < i  ID/gal        as  an  iri-furr-ow spray foliowez
                           SC/i_)           irrigation.    ftpply i  to 3 aaci-
                                            tional  times,  at  14  to  21 ca/
                                            ir.ter-vals,  oy ir.jection into
                                            sprinkler  iir.es or  furrow  irri::
                                            ticn,,  or  py  Paridec  applicator
                                            (1  to  c: incnes wiae>  placed  •:•'"
                                            tne soil   S'.'. rface  at  rie ^as^-
                                            tne piar.ts fC'ilow£_  witnir.  -»e
                                            nours  witn spr-ir, K  er- i:>r~ f'.>r  . "
                                            irrigat ion.
Issued:    i-06-86          I I I-1U3601 - 1 c.'
                                                          124

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                                    Coriioenc i um  of  wcceataoie  Uses

                                                 G X MM Y L_

             5 i t e  ar,g  Pest           DC'Saqes  ar.c     ~o i ef-a nee ,   use.   ^imitation?
                                         For-Vi.i i. a t 1 C'r, i s '

                ,1 " : : r,  ,,  c : r, t i nuec >
  ,_O~-iv't-           _/'::'  t -i r- i 3 s      TS^^J             S,_ \  -  use  iirnitec  to  ID,  ^ I ,   >_ -

                    t .-i r : - E:              ' .1  . D / g a 1        Fc. liar- a D o ^ i c a t i •:"• .    ^zic^v  «•-. e '
                                          Su/L-1            i ri sects  fir-st  appear  ir
                                                            s i gr, i f i can t  numbers  ar.c  r-eos-at
                                                            1^»  aay intervals   i *  r.eeaec.
                                                            fijpiv  in  S'.iff ic:ert  water  t •:
                                                            ootain uniform  c:>--er-Jce  t,  cr-,;
                P e a c n  (nonpearinc;
                                                            AoDly  t C' trees  t ~ at  will  r,;. r  z- f a -
                                                            fruit  w i t-h i n  i i  rii,;«r, t -, s  a. " t e r'  =- _, -
                                                            pl icat iC'r..   DC.  riot  treat  r- . a r t i f :.
                                                            stocK  .by root  C:P.
                                         Refer  to  TERRESTRIA^  NONFOOD  CRO^,  ( Or nanie--t a .
                                         Plarits arid  Forest  Trees;,   Ornament a i   Plants,
                                         for  use  ana  limitation  information.

/cl&OlSfiH     Pea r. i.i t E                                   O.ii  ppm  (peanuts,  pear, Lit  r u i i s '
                                                            i.C'  oprn  (peanut   forage,  peanut
                                                                       hay )
                                                            Apply 6 weeWs  after-  er.ier- pence
                                                            tnr-ougn  1 . (j  pound  per acr-e  for-
                                                            feit ar  apoiicatic.ri.
                                                            Pit-plaritiriQ  soil  app 1 i ca t i C"-i
                                                            tnrougn 3. C1  pc.urids  per-  acr-e.
                                                            Do not  allow granules to  cor.ie  in
                                                            contact with seea.
                                                            Do not  apply in  CP.
                  i_ar.ce  nefiiatodes  0. 5-c.1. 0  Ib/A   fit -p 1 ant i nq  arid  at-oegcing  soil
                  ^esion  nema-      ( 10'/.  G)          aop 1 i cat ioris.   ftppiy  i r,  a  7  men
                   toces                                  bar.d  or  in-fi.irrC'W  at  oiar.tirir.
                  Root -K nc't  nerna—                     If  r.eedea,   repeat  at  pegging  anc
                   toaes  (except                       irrigate  thoroughly to  ^a = -  gr~a^
                   Javanese)                             uies  o.ff  fc.iiace ar.a  ir.tc.  t^e
                  (Tnrios-i                                SC' i i .
                                                                               125
            Issued:    ci-u&-8£          I I I - 1 L'J-GL'1 - 1 3

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                             tP«  Comoenc i urn of  wcceptacie Uses
i.-e ana  Pest
                                     D o s a c e s ana
                                     For-r.i'.i i a~ i o n ( s
                                      'ol era nee,  use,  uimttati'
                         ( c on t i nuec
                                      ( £  i b / g <=>
N E Zi t< C
IM
-R i r, L r s -a T oees

 toaes  (exceot
 Javanese;
Sting nematoaes
T h r- i D S
                          ^  1b/aa1
                                          ^r-eDictrit  or  at-s:antinc  = :
                                          D i i c  g a. ions  ae--
                                                       acre.    Apoly first  soray 5 we=-£
                                                       after emer-gerice  anc  the  secc'.r
                                                       soray £ wee^s after  eriier-ger-.ee.
                                                       Concent r-at i ng the  spray  or, t~e
                                                       row  using  5  cone-type norz.es
                                                       oositiorieo  over-  arid  to  eac^  sice
                                                       of  tne  rC'W  is r-ecor.iriiericiec.
 l_ (-• J M U I--
     cur-ooear,
      rii i t e
     mcOaniei spider
      rn i t e
     Pear-  r'.ist mite
     Twospott ed
      so x cer-  rnite
                                      14 day prehar-vest  interval
                                      through  £. O  pouncs per  acre.
                                      Do not graze livestoc*  in treats
                                      orchards.
                                      Do not apply in  CP.
                                      Do not apply at  bioom or witnin
                                      50 days  after-  full  bloom, or
                                      fruit thinning may  occur-.
                                      Varieties otner-  than Bar-tier' an
                                      a'Pnjou  snoulc  be  testec  fcr- me
                                      possibility  of  russet ir.^.

                    1.5-2.0  iD/P   Foiiar-  application.   Ppaly  D/
                    (2  lo/gal       grour.a  equiornent  i r,  liiiu  to  £*•'.•'•.
                     SC/i_)           gallons  per  acre  wnen  rnites  rir- = '
                                      aopear.   Repeat  as  neeaec.    H  ci
                                      lute  application  is  recommence..
             Issued:    i-06-86
                                                           126

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                                             i urn  of  ftcceptaple Uses
             ^ i t e  ana  >-• e s 7
 os ages  ,? ••- a     Tolerance,
 or ',1 '-i - a r : :••- ' 5 ;
                                                                         Use,  _ '. r.i i t a t i : r. 5
                                                           0 D D i v  t c  trees  t T a 7  w i
                                                           fruit  w 1 t n : r.  1,1 rnor, 7-1 =
                                                           application.    C :  ^  : t  t •
                                                           oiaritir. c  s t •: c -  o >  f . •- t
                                                                                                  sea •"
Refer  to  TERRESTRIfiL NOrMrOCD  C ^ _ - .
Piar.ts ana  Forest  Trees^,  Or r.a Me>-t: ,?
for- use  ar,c  1 i rn i t a t i on  i nf orrra t i :•" .
                                                                                               -e" T a .
                 ?ppe>
IRACCUfi
                          peacn
                   aon i a
                  Peooer  weevi1
                  Vegetable  leaf-
                   m i ner
 . 5-1 . 0  i s/i
( £  1 o / g a i
 5C/L)
2. u
7  oay  prenarvest  ir,te--vai  t~---i"jz'
1.0 pound  per  acre  for  fc'i;^--  a -• •
pi i cat ion.
Do not  apply  as  a t^arisolar. t
water  treatment  G'.: r i »• g  pei-'ic^ZE  c •
slow  plarit  grow:~i s-.icn  as  *~^.e-'
ter.iper'atures  fall Qeiow  A5  F   (7.,
C > ,  or  crop  injury  may  '~es 1.11 t .
Do not  apply  in  CA.

Foliar  applicatiori.    P p o . y  in  a
minimum of 1 Ou  gallC'r.s  per  acr-e
wneri  insects  first  appear^.   Re-
peat  at  1  t c>  c.  weew   intervals  or-
as needed.
                  Ring  nerna t c^aes   tr-ansplarit
                  Root—^not  nerna-   water:
                   tC'aes  (except   0.5  iD/fi
                   Javanese;            and
                  Sting nernatodcs  foliar:
                  Stuooy-root        O. 5-l.C'  Id/
                   nernatodes         < «i'  lo/ga.
                  Sturit  nematoaes   SC/i_>
                   T'-arisplarit  water applicatic^ri  ar.c
                   foliar  application.    Apply  in a
                   minimum of  clOO  gallc^ris  of  trans-
                   plant  water  per  acr-e.    Uncer  very
                   high  nernatode pC'pu 1 at i ons,  fC'll'i'W
                   transplant  water apolication  wit n
                   a  foliar-  applicatiori  1<+ days
                   after transplanting  arid continue
                   as descrioec in  aoove L; = e  oat-
                   t ern.
            Issued:    c:-0£-
     I I 1-103801-15
                                                                         127

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                 EPA  Compete i urn of  Pccentaoie
   re  and  Pes*.          Dosages  arid    Tolerance.   Use,  L i •• : t ar i c
                           r or MM 1 a t i on '  3 '
                                               .        (nay)
     ea -'f ' : " r                               5_N-"1I  ana  OR:   £' 1  car prena-ves:
                                             iriter-vai  cnr-O'.ign  5 . 0  - :  r.cs  DE-'
                                             acr-e.

     i_esiC'r,  rieriia-      C5^'^J             Si_N  —  Use  liMitec  t •:•  IT I  ar.c  C-.
       toces              1.0—2.0 lD/P   Soil/foliar aoolication.    Purj.y
     flint  nemat oae     < i  ia/cai       as  mint  br-eans  winter- cor-n-a":c/
       (Long i per i.'g       £C/l_)           and  active  i- o o t  c r- o w t n  D e z i ' =  ; r.
       e i •:• r, c a r '.i s i                          a  n< in: m ij r.i  of  1C1  o a i i o n s  per
                                             acre.    Aooly tne  lower'  r-are  •: '.
                                             coarse  texturec  ^sancy;  £•:•-..=  ^r,-
                                             rnuiCK  soils  for   lesion or M i r -
                                             nema r c ces .   Opoly tne nic"i = r  ra^
                                             or,  fine  textured  (clay)  5:1.5  -.:,•
                                             rn i nr  riewa t C'de.    CPpplicatiori  t:
                                             neavy  soils for-  lesion  ne^at ooe;
                                             have not  proven  effective.]    cair
                                             fall  or  sorinWler  irr-igatior.  (0.
                                             to  1  men)  is  neecec  within 7
                                             oays of  treatment  to  move  cne
                                             active  ingreaient   into  the  rcct
Issued:   £-06-66          I I I - 1 O38O 1 - 1 6               128

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                   EPP,  Cornoenc i'-I'll  of  Pcceataole  Uses

                                      C' X H M Y i_

                  :           Dosaces  anc     Volgrar.ce,   Use,  i- i iv •. t a t i >: ns
                             FQ r-rnu ..at 1 or. ( s ;

        	                                   1. u  PCM  "-.Dineacc.es •
                                                   6 . O  pc1".  i p i nea c 3 : e  or a-'
                                                  1 0. O  ppm  ioinea33le  f i r a ;: >= '
                                                  5O  day  prenarv@=t  i "' *: e >•• •- =>  .  VN •. t ~  a
                                                  rna x i Mi.1.rii o *  MCJ .  ' '  ?•:.,- a c-  ci    ac ' ^
                                                  on  the  plant  cr-'oc:   •:••.  a  .-.'a - i >v."
                                                  of  li^.O po u rids  per-  ac-e  •:  •'•  t n e
                                                  ratoon  crop.
                                                  Do  not  a DD I y  i r  CP.

       e~.vp'.'C5   [S^J  soil:              Preplant  or- pi'Stoiant  s.^.
           i f O'r.-ii  nerna -   1 . C' —6. 0  1 D / P   a pp i i cat i on ana   f o i i a r a c z I i ca -
       toce                   or-               tion.    Ppo 1 y  ^. <:>  t o 6. 0  poun - ^
         tie  SC1 : i .     Plte'-ria-
                               SC/i_>             tively.  apply   1.0  t :•  6. C>  pc".'r,as
                                                  per-  acr-e  Or-.;.acrast  witnin  i   wee^
                                                  after-  planting,  or-  apply  1.0  t ;>
                                                  6. C>  pea-no s  per- acr-e c i rec t i y  to
                                                  the  soil  by or IP  irrigation  in-
                                                  jection  within  1  k-vee-  after-  plan 7
                                                  ing.    Suosecuent.v,   a p p . .•  i     T:
                                                  ••+. C'  pc'urias   per-  acre  c>  i  :   c
                                                  equipment  as  a  fo.xar =,-•••-  gr-c-w  fc^i   :"<•• i n-.
                                                  planting.    For-  tne  r-atocr cr~c~
                                                  apply  1  to   3  wee-s  afte--  nar-vett
                                                  •of  plar-it  crop  (Si_N- PR ; .    Piter-na-
                                                  tively,  apply  0.5  to <-+.O  pour. PS
                                                  per-  acre directly  t o tne  sc  i 1  by
                                                  drip  irrigation injectiC'n  at  !,
                                                  ^,   or  8   weet-<   intervals.     It    is
                                                  recofiirnenaec  tnat  these   suSsec, uer :
                                                  app i i cat  i ons  follow  tne  aacve  Dr-g
                                                  plant  or  pC'Stplarit  app  icaticn.
                                                  C'r-  a  star,aar-c   f urr i pant .

      .ijvi   ( riO'r.oear- ing;
                                                   fipplytC'treestnatwil.riitPC:?

                                                   pi i c a t ion.

                              Refer  tc  TERRESTRlPu  NONFOOD  CROP,   (Ornament±
                              Plarits  arid  Fci>-est   Trees),  Or-riarner"'t a 1  Piar.ts,
                              for-  use  aria  limitation  information.
                                                                         1  ?Q
Issued:   i-06-B6           I I I - 1 03801 - 17                   '^/

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            S i te  ar.g  Pest
Cornpena i urn  of Acceptance Lses

           OXAriYL

    Dosages  a^-d    Tolerance.  Use,
    Forr.iu 1 a t i on ' s )
                                                      ^ : rn 1t a t i o i
NEF&E-&H
I RAFPJP
    1 as
Colorado  ootato
 beet i e
F lest Peet i es
Golden riernatoae
 CS^N-NV]
Les i or* nema-
 t cdes
Potato leaf-
 nooper-
Ring nernatodes
 (except  w
 of  t n e
 Roc*ies;
RC'C'C - Kno t
 t C'Oes ( e xceot
                                   i. 0-6.0  1b/ft
                                    c <£• 1 b / g a i
                                    SC/L)
                                     ( 1 Or.  G)
                                    0. 25- 1.0  I b / ft
                                    ( 2 1 b / g a 1
                                     SC/L.)
                 Sting  neniatodes
                 Tarnisnec  plar. t
                  bug
                    '-'.  1
                    7  aay or'e^iar-vest  interval  t n r^; i.,--,
                    l.O  pound  per-  acre  for foliar- oj-
                    D i i c a t ion.
                    In — fur'rcw  sC'il  a^olicatir^r, .
                    tnrougn  <+.<'.> pounds  oer acre;  or
                    preplant  soil  aoplicatior!  fir.:..,;-.
                    8.  O  pounds per- acre.
                    Do not apoly  ir. CO.

                    Preplant  or at-planting  scii
                    application.   For  nernatoaes ar.z
                    eariy season  control  of  insect;,
                    apply 2.0  to  4.O pounds  per ac-e
                    in tne seed furrow curing  the
                    planting operation;  or,  apply  H.O
                    to 6.O pounds per  acre as  a Dana
                    or broadcast  treatment  (use
                    broadcast  for c o1d e n n e r n a t oc e)
                    witnin  1 week of planting.   inccr
                    porate to a depth  of ^ to  &  inch-
                    es,   ftpply .2  pound per gallon
                    formulation  in a minimum of  c.0
                    gallons  oer acre.

                    Foliar*  application.   For  insects,
                    apply O. 5 to  1.0  pound  per acre,
                    except  in tne  Midwest  and
                    Nortneast  where 0. c.5  to  1.0  Dounc
                    per  acre may  be usea  for"  Co - oraC'i
                    pot at o  beet 1e.  Apply  wnen
                    insects  first  appear  ana  repeat
                    at 5 to  7 day  intervals  or-  a =
                    needed.   May  be applied  by
                    aircraft  in a  minimum  of  **
                    gallons  per acre.
            i ssuec
      2-06-86
        I I I-103801-18
                                                                          130

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              r;lte  a r,c  nest
Cc-iYiDena i urn  of  PcceataOie  uses.

            Ox Ar-iYi_

                       ~G' . ef~ 2 r.ce,  'Jset
Dosages  ar.o
For'on.i I a c 1 C' r. ( =
                                                                                  L_ i m i t a t i or.
I R (H •_ H M
NEr&HH
N £ J E4 e M
NEG&HMM
      , c s ;
Cyst  nematodes
i_es i or.  nema —
  t oces
Rc'C't-knot  nema-
  todes  (except
  Javanese)
St ing   nema t O'Oes
(Thrips)

Cyst  nematodes
L_ a n c e   n e m a t O' C e s
Lesion  nema-
  t oo es
Ring  nematodes
Root—knot  nerna-
  tooes  (except
  Javariese)
Stunt   nematodes
           Ib/A
(  1 0V.  G )
bar,a :
0.5-1.0  1 b/ft
  C3£  in.   rc'w
  spacing]
   or
broadcast:
i. 0-4. 0  1b/«
(2 Ib/gai
  SC/L)
                                                                        ( soy pe=»fis,
                                                                       st f-aw '
                         not  cut  for  nay,  or-  ^eec:
                       treated  for-age  to   l'i ves v :>c « .
                       DC'  nc't  allow granules t •:•  c:'f; =
                       GC'Titact  witn seec;.
                       Do  not  apply in CM.

                       Preplar.t  or-  a t -p 1 ant i rig  soi-
                       appiication.   &ar.c  treatment.
                       ftpply  in  a  7 to  14  inch  b=?r-
                       1 ncor pc'r-a t ed or-  in— furrow.
                       Treat merit will  control  only
                       rnocerate  i n f est at i ons of  cyst
                       nemat oces.
                        P replant  or  at-plartir.g
                        app 1 i ca t i on.    Apply   in  1 '.'  to  IO
                        gallor.s  per-  acr-e.    HS  a ^,
                        in- fur row  barid  treatment,   apply
                        over- open  Or- ill  row   at  t n e
                        juncture  where  trie  seec:  is
                        covered  with  so i 1  to  assure
                        mixing of  the f ormu . at i on  witn
                        tne  soil  around  the   seed.    Or-,
                    a p o 1 y  t C' a  7  to  1 < J
                    the drill  areas  up
                    before planting  or
                                                                                        i nch  bane   i
                                                                                        t c-  1  weeK
                                                                                        at  plartinc
                                          c:  to  4  inc'iei
                                          Or-,   apply  =• -:    r>c *:  ris.
                5 pea rm i r, t
                   '.< a
                    See  Pepper-mi rt-  cluster

                    See  Cantaloupe  cluste
             Issueo:    £-06-86
     I I I-1036ul-13
                                           13

-------
               C.PP Cornpenc i urn of  ftcceotacle  uses

                               OXPMYL

Site  and  Pest         Dosages a"ci
                                                    Tc' 1 eranee.  Use,  Limitations
              Strawperr/
               St OC - '
                ( r\ o r-. 3 e a r1 n c
                                        ft^riy  tc> o 1 a r 1 1 s t n a t i~ i ; i  net
                                        bear fruit *M 1 1 n i n 11 montns  after
                                        application .   Certain  varieties
                                        of  st rawde'-r 1 es ar-e ser, sitive •: .;•
                                        oxamyl  exnibiting sever- e
                                        phytOtOHic syr.ipt Ofi-'a .   Kr.ow.
                                        sensitive var-ieties t n o t  s~i>: .c
                                        riot De treated  w i 1 1 oxaoiyi
                                        incl'-iae Bc'unty, Can.;. 5 a  (\r'i2£>i),
                                        Cavalier,  Dsrrow,  D'.irica,
                                        Ea>-iidawn, Ear^ligicw,  Ef.iczre,
                                        Hoiiaay, Mar'late,  Midway,   M;c
                                        l^ac, NY 1^*09,  Ogailalla,  Recgl.i.w,
                                        Recstar-, Sec'aoia,  Stark Rea,
                                        5'jr,r-ise, and Vies tar.   Otner
                                        varieties may  be  sensitive.   Tes
                                        '••r>  a small  scale  to aeterriiir.e
                                        sensitivity  prior to  ia^ce
                                        aool icat iori.
                                   Refer- to  TERRESTRIft^ NONFOOD CRO^.   (Ornamental
                                   Plar.ts  arid Fc''-est  Trees),  Ornamental  Plants,
                                   for-  use  ana  limitation  information.
              Sweet  Potato
t Lj i
     ftC'Ot— Priot  nema-  preolant:
      todes (exceot   *>. 0-£. 0  lo/ft
      Javanese)        (c:  lo/gal
     Soirai nema-      SC/D
      t oaes            (10% G)
                          or
                        i n-f urr-C'W :
                        c. O-4. 0  i o/ft
                        (i  Ib/ga.
             '.i. 1
             Preolant  soil  application tnrougn
             6.'.'  pounds per- acr-e:  or,
             at-plan ting  (in-furrow)  soil
             application  through  4.0  pounds
             per  acre.
             Do not apply  as a  transplant
             water treatment during  periocs of
             slow plant growtn  such  as wnen
             temperatures  fall  below  45  F  (7-1
             C),  or crop  injury may  result.
             Do not apply  in Cft.

             Pr-eplant  or-  at-planting  so;,.
             application.   Apply  as  a  preplans
             broadcast or banp  treatment
             (using  proportionately   less
             formulation)   in  a  minimum of  10
             gallons  per  acre.   Ppply  w 11 n i n 1
             ween of  pi—nting  and  incorporate
             to  a aeatn  of  4  to 6 incties.   Or,
             apply  in—furrow  in a minimum  of
             1C"J  gallons  per  acre of
             transplant  water- d r i r, c  tne
             P i a r> t 1 n g  of  Slips.
           Issued:   £-06-86
I I I - 1
                                       1 -
                                                                          132

-------
                                       CornpenciuM  of Acceptance  uses
              '=__- t e a ng  Pest
                                           Dosages  and
                                           r I'l-riiu i a C 1 Of, ( S '
                                               .erance,  us& .  ^. i M i t a t i <
                                                               Ic..11  Douncs  per-  acr-e  oer  s,e-
                                                               f r, r~  foliar-  a D D 1 1 C 

I fl< p A A (3 l
NED&CA

IGfiE- AD
N'_ H H cr M M
.UHFHi- n
      cs  C a u N j
Cc> 1 or a co  DC'tatC'
  beet 1 e  C5i_N]
Flea  oeet i es
  C o^N j
Gr-eeri  oeaci
   i i a r  apoiicacic''.    A D p . y   : r.  a
                                                               rn i ri i dium  of   i(j>j  gaiioris.    i5_^  -
                                                               Ws  or  as
                                                               neeced.]
 .NM^A;
 ; ^ H A A;
 '•tJE-t:

i( .
 'tcr^r
                    (Aphids)
                    ( F i eaDeet ies)
                    (i_ea f m i ners )
                   ftem f orr.i  r.erna-
                     toaes  (except
                     Javanese'
                   5 t i rig  ne'.ia t oces
                   St '.i DOy-root
                     r.eriia t oaes
                   Stunt  r.eMat odes
                    ( wnit ef1  ies)
                        4 . 0 - £ .  0  1 P / O
                          C 1 6-<±^4  i r,.
                         par.c  wiatnj
                           or
                        6. i.''-a .  0"  i D / A
Pr-eplar, t  soil  application.     T.-. o.
oucniy  i ncC'rpCT-a t e  to  a  ceorn  .;.
^  t C' £  incnes  i fiir;iec i a ^ e . >   art^r
apo; icac iori.
                          1 <.'%  G )
                           1-06-86
                             III- K)38
-------
                                 Compendium of  Pcceptaoie
            Site  ana  Pest
                    Do sages  and
                                      '•:•. er-ar;ce,  use,  t_ i m •. t at i •:••'.s
                       i c o
I PML-'-"-J>1'
[ f^, M h-< M '_: t-i


J E U P CM i-1
vi E J & L, E- P

! M P A H • j i-1
                  C'Ot -K not
                  t odes
             i n u e a '

             Nj      L 5 ^ N j
                    (!' . 5 — c. . ' J
                    (ilo/g
             nenia-   SC/i_)
                                     bi_N  - Use iimitec
                              i D / H   Soil  application.
                              1       to trie  SC'il  by aria  irriaat
                                     Ppoly with  first  irrigatior.
                                     tne  field at  7 to  10  davs.
E".i t't-i-' w i no
 toaes  [S^Nj
i_ea f rii i ner-s
 CSi_NJ
Lesion  r.erna-
                    CS^N]            SLN  - Use  limited to  HI.
                    4.0 — 8.0  ip/P   Soil  application.   Poply  c i r e c t . \
                    (c. ip/gai       to  the  soil  by  drip  irrigation.
                                     Ppply within 1  wee-'  after plant-
                                     ing  and  repeat  at 14  to  30 aay
                                     intervals  as needed.
•j E u b C
RC'C't — K no t
 tC'Ces  CS-Nj
Sting  neniatodes
JEO&CP
Root ->< not
 toaes  C5i_N]
                 -  CSLN]
                    O. 75-1.
                     lo/fi
                    ( c.  i d/ c c
              w a c e rme i o r.
Si_N  - Use  limited to  CP.           '"
Soil  application.   Pppiy  0.75
pound per  acre  using  an  injection
shank  immediately adjacent  to the
planter furrow.   Ppply  to  mcist
soil  ana follow as  soon  as  D<: : -
siPle with  either- sp^inK.er  or
furrow  irrigatiori water-.    M^oiy
1..E5 pounps per- acre as  
-------
                        Coriipena i uni of Mcceptapie  Uses

                                    0 x M f v ;_
                            Dosages ar,q    " o . e r a r, c e ,  L' s e ,   i_ i M 1 1 a t i o r\ s
                            Form i.i 1 a - : : r, • s -
      >- * ea Deet i es
      Lesion neriia-
        t oaes  (except
        J a v a n e s e >
      Root-unot   nema-
        todes  (except
        Javanese;
Prep i a r-it :
il. C-b. 0  1 p / P
( c.  1 D / g a i
 SC/L)
  ( 1 0%  G)
    or
t r-
 gri  5 wee«s afrer-
t r'a risp i ant i r(g  t n r'O'.i Cn  1 . ' '  DO'.inc
per  acre;  aria  t rar.^c 1 art  i~ate'
a3D i i ca t i on  tnrougn  L'.5  ^i''.ir.a  DS--
acr-e  or"  nreolar-.t  s: i 1  <=OD! i r =? - !•:•'.
tnr'O'.ic1"!  6. '!'  DC".; nis  ?e'- £»cr'e.
Over" -a 3D 1 i cat i on  fiiav ca'.ise s t <.( r"> ~ -
i nc  of  tobacco.

Oreoiarit  soil  a 02 1 i ca t i on, t^^-'iS-
olarit  water  apoiication,   anc
foliar  application.   Tr-arisplarit
water- application  may  De  apoliec
alone or  following  prep 1 ant  soil
application.    Foliar applications
can  follow t ranso 1 ant  water-  or
preplant  soil  applications.    Pp-
piy  as  a  prep I a nt  row  treatmer~
i r-, an  18  t C1 2'4  ir.cn  pane!   : '  a
NT i n i rni.irn C1 f £0   gallons  pe--  acr-e
 (12,OC>0 row  feet),  or-  as   a  bro-  acr-e.
Incorporate  to  a deptn .;• f  **   t i  £
iriches  by  rc^ary tiller-  for-   row
treat merit  or  by disci rig  for   prcaa
cast  and  bedding.    Transplant
within  d.^  hour's after  soil  treat
rflent.   CSLN-NC:   May   be  t a r, -
mixed  with  1.0 pouno   active  ingre
dierit  aiacirion  in  broadcast  SP--^^
 t C1  control  wireworms.  -   fts a
 tr-arisplant  water-  application,  az-
 Piy   1 n a  minimurii  of i >'.•'.>  caiions:
 C'f  t r-ariso 1 ar>t  water per-  acr~e
 using  the  low  rate  fcr  S,c,'."''
 plants  per  acre  or  tne  n i gn   --ate
 for-  S,t.'OO  plants  per-  acre.    HPJ.
 
-------
                              Comoendiurn  of AcceotaoLe Uses

                                        OX AMYl_
           Site  ana Pest
Dc' sages ana
F o r m M 1 a t i o n ( s )
                        Tr. ler~ar.ce.  Use, Limitations
               •: sacc :•  < cont i nued
                                                 a  seconc  directea  spray  ir.  £1., to
                                                 ^•O gallons  deoending on  pia".-
                                                 sire *+ to 5 wee^s  after-  t>-ar,s-
                                                 plant ing.   The  use of 2  nozzles
                                                 positioned  over  aria to eac^ sice
                                                 of the row  is
                        a i .Plarits  ana Forest Trees)
/ .Z^O
/ '.'
Plants
                   ias  (in-
                 cluaing  aople
                 aonia  ana
                 green  peacn
                 aphid)
                &1ac^  vine
                      i1
                        gnats
                Japanese  beetle
                Leafhoppers
                Leafminers
                flea 1 yDugs
                Mites
                Royal  palm bug
                Sea i es
                Th rips
                wn i t ef-1 i es
O.5-1.O  lb/
  1OO  gal
  Cmax clOO
  gal/A:
  or
1. 0-c:. 0  1
  [max 60O
  gal/A:
  or
0. 375-0. 75
  oz/5-14
  ga1/1,000
  so. ft
 (2  Ib/gal
  5C/L)
                        For use  only  in  cornrnerc i a 1
                        houses arid nur'ser-xes.   Do not
                        apply tne sc>l uole/1 iquia  cc'
                        tr-ate f orrnu 1 at i on t o  interior
                        plantscapes or  potted  plants  in
                        or around domestic areas  such  as
                        homes, shopping  mails,  or- commer-
                        cial buildings.
                        Treat and observe a  few olants
                        prior to large-scale  application
                        to a single variety.   Do not  ao-
                        ply foli'ar treat merit  t o plants
                        unaer water- stress or  plants  not
                        actively growing.

                        Foliar  application.   Apply  as
                        needed  to maintain control.
           Issued:   £-06-86
            I II-1O38O1-24
                                       136

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                                     Compena i urn cf Pcceot.apie Uses

                                                  GXPMY'L.
                                         Dosages  ana
                                         F ormu j a t i o n < s
                                          'ol era nee,  use,  ^
                                                                                      i 1 a r i o
NEBPPP
                       '.g_^~ _g_-  - 1 a ^ t s  (cont inuea)

                                         pre p1 ant :
                                         6. O-cO. O  1 b/ft
                                            Or"
                                         soil  rn i x :
                                         O. c.-O.  6  or /
                                           C'J. ya
                                            or
                                         p O s t o i a r. t :
                                         6. O-c:0. O  1 b/P
                                            Or
                                         0.£-2.  1  g/ 1O
                                           sc. ft
                                          ( i (J7.  G >
Burrow i ng  nema-  preplant:
  todes              £. 0-8. 8   Ib/P
Lesion  nema-        C r>i i n £0
  toae^                gal/P]
Root-wnot  nerna-   (S   Ib/gal
  tC'Ges  (eHcear     SC/L)
  Javanese;             or
Stir.g  neriiatodes  6.0-2ij.0  Ib/P
Stur.t  r.ematoaes   (10%  G)
                          or-
                      SC1 1 i  mix:
                      0. 69  o; / 1 C'
                        gal
                         or
                      0. 17-0. c.2  02 /
                        CM. yd
                       (c:   1 b/ga 1
                        SC/L)
                         Or-
                      (j. I-C'. £  02 /
                        cu. ya
                       ( 1O*  G)
                         Or-
                       f o 1 i ar- :
                      i;>. 5- 1 . o  i c/
                        ( <:>':>  gal
                        L.nax  2. 'J
                                           i£  1 b/ ga :
                                           SC/L)
Sc'il  aoolicaticr-i.    inpoiv  as  a
prep 1 a r. t  so ; i  a DD 1 i c a t i on  ar.c
i r'CC't- a or- a t e  to  a aeotn  of  *+  t c  6
inches.   If  apDiiea  in  a  oana.
use  Dr-opor-tioriateiy  less  fc'rTiv.i —
1 at ion.   Or-,  apply  as  a  s o i 1  r.i i K
wh lie t i.imb 1 i n g  in  a  sell  rn i x e'~ -
Tne  rate  given  is  eauivaient  tc>
£/. O  t C'  iL'. ij  pr. i.irics  per  acre.    Or-,
aoply as  a pc s r 3 i a r, t  soil  acoii-
cation.   I rnfiiea i a t e 1 y  after- appli-
cation,  apoly 1  i ncf~i  of  C've-'^eac
i r--- i g a t i on t c- t n oro LI g r. 1 y  was^
granules  off  foliage  a rid  into  t ne
soi 1.

fay  Pe  applied  as  a  pretransolant
soil  application,   postplant  soil
application,,  as a  drench,  or  as
root,  corrn,  or  Dulb a i p.    Fc'iiar
applicatiC'ri  may be usea  alone or-
a  supplemerit  to the a f orernent i on-
ec   apoiicatioris or other- nernati-
cide treat riier-its.   When  trariSPlarit-
ing,  set  plants into  soil  within
c.**   hC'Ur-s after  aoplication.    Ap-
ply  as  a prep 1 ant  soil  applica-
tion and  incorporate  to   a  depth
of   ^ to &   inches.    If  appliea  in
a  band,  use  proportionately  less
formulation.   Ppply  as  a  soil  MIX
while  tumbling   in  a  soil  rnixer.
Tne  rates   given are  equivalent  to
ti. 0  t G'  .10. C1  pounds  per  acre  ae-
pend i r.g upon  f orrnu 1 a t l on.    For
 f •:  1 i ar  application,  aoply ^   tirnes
as  a ailute  spr'ay  at  c: t o 3   wee*-
 ir, ter-vals.   Ppply   first  spray  at
 first  f i.i 11  leaf  or-  wneri  plant   is
 in  active  growth  pnase.     Pac  a
 suitaole  spr-eader-  sticker-.    Ppci/
 as  a  p'i'S t  pi arit   soil   application
 followed   immediately  Oy  1  i r.ch  of
 overhead   irrigation  to  thoroughly
 wasn  gr-anuies  off  foliage and
 into  the   SC' i 1 .    Ppply  as  a  iiauic
 C r' e^c"^  usinc  ^  t C'  8  f i i.i  i d C'ur.ces
              ssuec
                                              I I I-1038>">l-i5
                                                                                      137

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                    C.2C  Lc freer.- : '.ir,-.  -; f  ficceptat-le Uses

                                        u x fl ""i Y,_

 S i r e  £•' c   3es-           DC sages  ar.p    Tolerance,   Use,
                               ~ : r".i .1 . a t ;on(5;

    _•':?' e- - t ^   - . => r t s  v c :• r. t i n ..i e c .'
                               pis-.plar. t        of  solution pet'  &   ir.cn  oc. t;  of  i
                                = c i . :            to  <*  f 1 '.i i G  ounces   cer-  <*   i r.cn
                               t. ''-c.'.1. '.'  ID/M DC't.     As  a  o i p,  place  r-r.crs,
                                 or-               cor-rns,   or-  o i j i b s   i fi  the  solutior,
                                minutes.   Use  tne
                                sa.ft            higher-  rate ana   lorvger-  sc^a^ir,a
                               (!'.)%  G)           time  fc>r-  mc'r>e severe  nernatoce
                                 or-     *         infestation.
                               a '-er.cn :
                               '0. £'5  i D / 1 C'O
                                or / £  i r, .   pot

                              '!•. 0. 0 1 15   c r / 4
                                1 r. .   COt
                               (I  . 5 '  ca i
                              C : p :
                               •.  ^- 1 .  >.'  1 b/
                              O.  275-0. 7
                                o r / 5  gal
                               < £  1 b / o a 1
                                5C/L)
Issuec:    i-0£-8£           I I I -103S01-S£                          138

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                          - e ^c :  .i'i o *  ficrestar.e  uses
                                                           ,   i~se,  _ i •.• i r a t i :
- c- ^	
                                                  AoD.y  to  tr-ees  ar,c  st'-^wDe
                                                  t!"iit   t^it^ir-^
                                                  1 £  mo n t h s  after-  a D r ^ i c a r  i •:• r-,.
                                                  foiiowiric  s t r-aiNDer' r- i es  ar-e  v. •-•: w
                                                  to  be  sensitive  to  C'xaMvi  ar,c
                                                  ni i c ^ t  e M n i o i t  p n y t C' v C' x i c  s y 01 D -
                                                  t orns :   Bour-ity,  Can'i'DcS   ('^ Y 1 3££ ' ,
                                                  Cavalier,  Dafr-C'w,   D u ri i o p,  Ear'ii-
                                                  Ga w>,   Ear'ligl'i.vv,  Efi-jire,   M>;. . i '2 a
                                                  r^ic.aric,  i^icwav,  Mic  rrac,  N'
                                                  i^i.'9,   Ogali?.ia,  Rea g ; ow ,  Rec-
                                                  s tar.   SecMC'ia,  Star-H  Rec.  Sur>-
                                                  r-ise,   ar.a  Viestar.

                               e*er-  to  GPEENHQL'SE  NONFOOD  CRO^>.   (Drnaroent a i
                                1 ar. t s  ar,c:  F .:•!•£? 5 t  Tr-ees > ,  Or name "it a i  Plants,
                                :•'-  M se  a •" c   i i M i T a t i c r,  i r. f or-nia t i or-,.
Iss uec :
                                   I I I - 1O56'  i -17
                                                                                  139

-------
                             ^ - -  •_<; r i .T e'::. 'i  •;*  Acceptaole  Uses

                                             G * h ^ y •_

             iite  arr  -e ;-          Dosa:&=  ard'    ~o»erance.  Use.  i_ i rn i t at i ons
                                      ~ : •-••'.! i at i :>r (5)
                                                      rees )
                                                        For  use  only in  commercial  green-
                                                        houses and  nurseries.   Do  nor:
                                                        apply tne  soKiole  concentrate/
                                                        liauid formulation  to  interior
   •  IMK;;,II                                              pi ant scapes or  pcittea  plarrts  i n
xi iu(-i(':3CH                                              or ar-ound  domestic  areas  sucn  as
/- I'.ilfcLM                                              homes, snooping  mails,  or  comn-er-
/ 32'ii'CKjAA                                              cial  buildings.
                                                        Treat arid  observe  a  few  plants
                                                        prior- to large-scale  application
                                                        t •: a  single variety.
                      ids  (in-       CSLNJ            SLN  - Use  limited  to  Fl_.
                   eluding  a^ole   0.5-1.0  lb/     Foliar  application to greenhouse
                   aphid  and         100 gal         grown plants.   For i nsect =>,  apply
                   green  peacn       'Crna* £00       as  needed  to maintain control.
                   aphicr^             gal/ft]'         Greennouse  must be completely
                  &lac*v:re          or-             cl osed  for  at  least d. hours  fol-
                   weevil            '. . '!'-£. '".'  1 p / O   iC'Wiro  treatment.
lOfrFPfifi          ~ LI r. g'.i s  CJ'ICI'TS       [fiiax 6'!'0
                              jeet 1e   ca i/w]
                              -s         or-
                   ea^r.i: ^e-s        '>. 375-<:>. 75
                   'taiypugs          or/5-l^» gal/
                   :t es               1, OOO  sc. ft
                   'oval  D a I n  p u g    ( £  1 b / g a 1
                      les           •   SC/L)
                      i PS
                      ". e " 1. i e s
iss.iec:   c-0£-86          I I I - 1C'380 1-£6
                                                                                     140

-------
                                        Comoena i urn of  HcceotaQj.e  Uses
                             Be_§_t_           Dosages ano     Tolerance,   Use.  L. i rn i c at i ens
                                             .-•:•-• MU 1 a - i on '  s )
                      ^-S—g " ' .  1 A-O. i 9  ID/   p 1 a n_t  S'T' i 1  aoalicatiori  ar.c  i r,cc>r -
                      •-'-'t-K",.;. t   r-ierna-   i , ijCaj  sa.ft    pc>rate  t c>  a aectn  of  *+  to  &  inc~i-
                      toaes   (except       or                es.    If  apo.iea   in  «s  paric,   use
                      _avanese>          5c>il  mix:         orooor-t i or.at e 1 y   less  f C'r-fin.t : a r i on .
                     - - - r-. g  neriia t oc es  '!'.  c.-' >. 2 c z /     Or-,   aco 1 y  as  a  so i .  m i v  wn i 1 =  t Mm
                                              c '.i. v C             D 1 i ri g   i r.  a  soil   mixer.    T n e  rare
                                                or-                given   is  eauivalent  to  &.O  to  9.0
                                             cost P  1 ant :       POM rids  oer  acre.    Or-,  apply  as  a
                                             £.O-8.0  lc/ft    post Diane  soil  application.    Im-
                                                or                mediately  after   aD3iicatic>n,   an-
                                             1 '.  i. ^» -'!'. 19  ID/   D 1 y  i   i r.cn  of  :- ver-nead  i r-r i g a 'c i c>n
                                              1 , OOC J  sr . f t    to  t norou g~i i y  wa s.~i  gr-ari LI 1 e s off
                                                or                foliage  arid  into  the  soil.
                                             0.  £-'j. u  g/ 1O
                                              sc. ft
                                             ( 1'!'•/.  G)
                                                                  5_K  -  use  limitea  to  UM.
                       'e-,i-? t •: c e            ij .  1 S-C'. 5 75       Foliar app i i ca t i on  to  areenno..ise
                       =<-^-           «      oz/5-1**  gal/  grown  Rieger  BegC'r.ias.    Masly  to
                                              1OO  so. ft       foliage  as  a  directeq  spr-ay.    MD
                                             (c   ID/gal        ply  at 2  t c>  A  ween   ir.ter-va^s  as
                                              SC/L)             nee^ea to  maintain. cc>r.t ro i .
                                                                  Gr eenn C'Lise  nn.ist  3e cC'r.io 1 et e : v
                                                                             fc>r-  at   least  c:  ho'.ir-s  foi-
                                                                             t r~eat riient .
                                                                                                   141
               ssuec:    2-06-86            I I I - 1 038'.'1-13

-------
                                        HCCBDT e»C I'e  USSS
                              ^ies an
                                             olerance.  Use.  ._ i m 1 1 at i •: ns
                   .              1 , OGO sa . ft
      Biacw vine           or
       wee v i i            so i i  mix:
      & u I- 1- <:• WM i r, c riema- O.i-O.Z  oz/
       t •: CP?              c-. .  ya
      Pone '.is  c r,ese  oeetle o-i'St D 1 ar,t :
      i_ea f nooDers       6. '.''-8. 0  ID/ A
      Lea f m: ners           C"-
      i_esiC'ri  r,ema-     0. l^-ij. 19  lb
       t •••c. &s               1 , 'i";"!! sc . f t
      fea 1 / D'.l C S            Cr-
      r : t es              i:>. £-'.'. 8  c/ I1.'
      ficct-Kr.cr ne'iia-   sc.  ft
       toaes  (excert    <10v.  G)
             Soil  aoolicatiori  to  greerinouse
             g^C'wri plarjts.   Aopiy  for i nsec t s
             arid  nernat C'Qes.   Mo^.y  as a  ^r-e-
              plant  soil  app 1 i cat i on  and  incor--
              pc'r-ate  to  a aeotn  of  A  to     : ncn-
              es.    If  appliea  in  a  bane.    :e
              ~r-C'2Or-t i C'r.a t e 1 y  less  f emu., . 3 - i on.
              Or-,   apoiy  as  a  so i 1  m i x  wnxie c MM
              aling  in a  soil  mixer-    Tne  rate
              given  is equivalent  to  6. 0  to 9.0
              counds  per'  acre.   Or,  apoly  as  a
              oostpiant  soil  application.   Im-
              mediately  after ap3 i i cat ion, ao-
              b '. y  1  men  of  overnead  irrigation
              t C'  t ho'rougn 1 y  wasn  granules  off
              foiiaae ana  into  tne so i i .
      R'i>y a i  oa i M  D
      Sea i e s
      St ing  neroa t C'
      Tnr- i 23
                  K  ^ I X ftPP'_ I CAT I GN5
            Qpplication
                           Refer to
                                                 CRG_P
                            ( ftqr i CM i t ijr a
                                             Cantaloupe  CSLN],  Ceier-y  :5_'*-,
                                             Citrus Fruits  C5i_N],  Cot tor,
                                             CS_N],  Cucurnoer  [b'^Nj,   n   evcew
                                             Melons 
-------
       _r, c  P e s T
                                    :• . ef- a
                                                  143
Issuec:   ^-0£-8£
                        I I I - I 028'.- : -2 1

-------
                                    -,- i (.mi  of  Hcceotao.e  Uses
          g  of  ^egis-.ereo  Pesticide  Products  Dy   For HIM i at i on

                                   ec: i a t e
                  e - *. . y  unavaiiaole   for  review
       O00352-'.iO27 i     G<.'076'3-0052:4      GO
       O < '.> 3 7 7 3 - GO 2 5 3 «
          «* s i.i s D e n a e a

    . a / q a .   ( 2 <* % )   s o i M D i e  c o n c e n t r- a t e / 1 i q M i a
    c > a.v » i   (1 i.>56O 1 ;
       000552-O0372
                                        AZ80O051    AZ8lC"J25    ftZ850i:'O8    ftZ850'J;'
                                        Cft730i:>l7    Cft8i:)0<;>62'    Cft80OOb3    CPSi.HJ.t"
                                             00001    CT780002    CT73O001    DE810011
                                        FL7£i;iC>l3    ^^770033    Fi_77C'C)i+4    FL78IJ047
                                        FL&lOC)i!i2    Fi_8lO|."*2    H173i!"!'i.">6    Ml8lOOG9
                                        nl 81 00 13    M I 82OGi.' 1    ID63»JOl3    luSOOOOt
                                        M I 77<.>O i 0    M I 62''!'022    M I 64i'.)(!iCi5    -M I 850003
                                        ^CSl'JOOS    ND73(!)C'22*  NJ8A(.ij,.
       0025    OK 64 GO 20    Pft78i".nJl
                       OC'33    PR78O003    PRSC'Cn
T X6**'!".' :'.'   V&780G18
vT73l'"''l''5   V782i">i'>i''3
                     r . /   .o-,a v a i  . ao I e  for-  f"ev i ew
Iss'.iec:    2-"t-5i            1 I I - 1 0380 : -22                     144

-------
                                                        0 x nr-1 r _
  l-ist;rc   T -   Derive   I 1-1 5 r- e c i e ^ t  < =
i c ~   "lav   be   I r. c i u c e c   i r    , a " --   "" i  " e =
                                                                                                            E <-'*-<   i^cce z ~. a - .  e
                           cia:::nor,   iISO)
                                                                                                      , U - c i e T -, v i   G - • I  - i :
                                                                                                      -'iDv . — i -r.ie t ~  . -  ---
                                                                                                      y i~ i :<• i ^ : " s .  ;    3 i •:  = -
                               ,%ar,le
Issuea:     £-O£-S£
                                                  I I I - :  O2S-
                                                                                                                     .  r

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      APPENDIX IV
BIBLIOGRAPHY APPENDICES

-------
                             BIBGUIDE-1

               GUIDE TO  USE  OF THIS BIBLIOGRAPHY


 1.   CONTENT OF BIBLIOGRAPHY.  This bibliography contains
     citations of all studies considered relevant by EPA in
     arriving at the positions and conclusions stated elsewhere
     in the Standard.  Primary sources for studies in this
     bibliography have been  the body of data submitted to EPA
     and its predecessor agencies in support of past regulatory
     decisions.   Selections  from other sources including the
     published literature,  in those instances where they have
     been considered, will  be included.

 2.   UNITS OF ENTRY.   The unit of entry in this bibliography
     is called a "study."  in the case of published materials,
     this corresponds closely to an article.  In the case of
     unpublished materials  submitted to the Agency, the Agency
     has sought  to identify  documents at a level parallel to
     the published article  from within the typically larger
     volumes in  which they  were submitted.  The resulting
     "studies" generally have a distinct title (or at least a
     single subject), can stand alone for purposes of review,
     and can be  described with a conventional bibliographic
     citation.   The Agency  has attempted also to unite basic
     documents and commentaries upon them, treating them as a
     single study-

 3.   IDENTIFICATION OF ENTRIES.  The entries in this bibliography
     are sorted  numerically by "Master Record Identifier," or
     MRID,  number.   This number is unique to the citation, and
     should be used at any  time specific  reference  is required.
     It  is not related to the six- digit  "Accession Number"
     which has been used to identify volumes of submitted
     studies;  see paragraph 4(d)(4) below for a further  explana-
     tion.   In a few cases,  entries added to the bibliography
     late  in the review  may be preceded by  a nine-  character
     temporary identifier.   These entries are  listed  after
     all MRID  entries.  This temporary  identifier  number is
     also  to be  used whenever specific  reference  is needed.

4.   FORM  OF ENTRY.   In  addition  to  the Master  Record Identifier
     (MRID), each entry  consists  of  a  citation  containing
     standard  elements followed,  in  the case  of  material
     submitted to EPA, by a description of  the earliest known
     submission.   Bibliographic  conventions used reflect the
     standards o  the American National  Standards Institute
     (ANSI), expanded to provide  for  certain special needs.
                                                        147

-------
a.  Author.   Whenever the  Agency  could  confidently identify
    one, the Agency has  chosen  to show  a personal author.
    When no  individual was identified,  the Agency has
    shown an identifiable  laboratory  or testing  facility
    as author.   As a last  resort,  the Agency has shown
    the first submitter  as author.

b.  Document Date.  When the  date appears as four digits
    with no  question marks, the Agency  took  it directly
    from the document.  When  a  four-  digit date  is -followed
    by a question mark,  the bibliographer deduced the
    date from evidence in  the document. When the date
    appears  as  (19??), the Agency was unable to  determine
    or estimate the date of the document.

c.  Title.   In  some cases, it has been  necessary for
    Agency bibliographers  to  create or  enhance a document
    title.   Any such editorial  insertions are contained
    between  square brackets.

do  Trailing Parentheses.   For  studies  submitted to the
    Agency in the past,  the trailing  parentheses' include
    (in addition to any  self- explanatory text)  the  fol-
    lowing elements describing  the earliest  known submission:

    (1)  Submission Date.   The  date of  the earliest  known
         submission appears immediately following the  word
         "received."

    (2)  Administrative  Number.  The  next  element,
         immediately following  the word "under," is  the
         registration number, experimental use  permit
         number,  petition  number, or other administrative
         number associated with the earliest known  submission,

    (3)  Submitter.  The third  element  is  the  submitter,
         following the phrase "submitted by."   When
         authorship is defaulted  to the submitter,  this
         element is omitted.

    (4)  Volume Identification  (Accession Numbers).   The
         final  element in  the trailing parentheses
         identifies the  EPA accession  number of the volume
         in  which the original  submission of the study
         appears.  The six- digit accession number follows
         the symbol "CDL," standing  for "Company Data
         Library."  This accession number is in turn
         followed by an alphabetic suffix which shows the
         relative position of the study within  the volume.
         For example, within accession number 123456, the
         first  study would be  123456-  A; the second,  123456-
         B;  the 26th, 123456-  Z;  and the 27th,  123456-  AA.
                                                 148

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                      OFFICE CF PESTICIDE PROGRAMS

                   REGIS~?,A~I:N S'ANDARD BIBLIOGRAPHY

        .a,ions  Considered to be Part of tne  Data  Base  Supporting
                Registrations 'Jnder the Cxanyl  Standard
           r ' - . - .
 OCC28T23  E.I.  du  Pont  de Nemours & Company (1974)  Metabolism  of  Cxamyl.
             Summary  of  studies 097651-3 through 097651-F.   (Unpublished
           . study  received Jun 14, 1976 under 352-372;  CDL :G9?651-A)

 00023732  Harvey,  J., jr. (19757) Metabolism of 14C-Cxamyl  in  the lactating
             Goat.   (Unpublished study received Jun 14.  1976  under 352-372;
             submitted  by E.I. du Pont de 'lemours L Co.,  Wilmington,  Del.;
             CDL:097651-F)

 00030920  E.I.  du  Pont  de Nemours & Company (1977)  Residue  Data:  Soybeans.
             (Unpublished study received May 30, 1980 under 352-372;  CDL:
             099443-F)

 00036935  Atkins,  E.L.;  Greywood, E.A.; Macdonald,  R.L.  (1975) Toxicity of
             Pesticides  and Other Agricultural Chemicals to Honey Bees: Labo-
             ratory Studies.   By University of California,  Dept.  of Entomolo-
             gy.    ?: UC, Cooperative  Extension.   (Leaflet 2287;  published
             study. )

 00037130  Holt,  R.F.; Pease,  H.L.  (1974) Results of Tests on  the Amount of
             Residue  Remaining on  Treated  Crops: "Oxamyl!.  Includes undated
             method entitled:  Determination of  Oxamyl residues using flame
             photometric gas  chromatography.   (Unpublished study  received Uun
             25,  1975 under 5F1650;  submitted  by E.I. du Pont de  Nemours &

 00039511  Harvey,  J., Jr.; Gerike,  P.  (19??)  Biodegradation of 14C-Oxamyl
             in  Peanuts.  Interim  rept.   (Unpublished study  received on un-
             known  date  under 3G1349;  submitted by E.1.  du  Pont  de Nemours  a
             Co.,  Wilmington,  Del.;  CDL :093610-J)

00039513  Manlove,  L. (1973)  Oxamyl  Livestock  Feeding  Studies:  Milk and Meat.
             Unpublished study received on unknown date under 3G1349;  sub-
             mitted by  E.I. du Pont de Nemours & Co.,  Inc., Wilmington, Del.;
             CDL:093610-L)

00040494  Harvey,  J., Jr.; Han,  J.C.  (1977) Decomposition of Oxamyl in Soil
             and Water.   (Unpublished study  .ceived Jul 21, 1977  under
             352-372; submitted  by E.I.  du P  nt de Nemours & Co.,  Wilmington,
             Del.;  CDL:096301-A)
                                                               49

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                       OFFICE OF PESTICIDE PROGRAMS

                    REGISTRATION STANDARD BIBLIOGRAPHY

       Citations  Considered to be Part of the Data Base Supporting
                 Registrations Under the Oxanyl Standard


  MRID      CITATION

  00040496 Harvey, J.,  Jr.; Bellina, R.; Morales, R.; et al.  (1970) Metabolism"
              and Biodegradation of Oxamyl.   (Unpublished study received Jul
              21,  1977  under 352-372; submitted by E.I. du Pont de Nemours &
              Co., Wilmington, Del.; CDL:096301-C)
                                                                             il
  00040592 E.I. du Pont de Nemours & Company, Incorporated  (1976) Livestock
              Feeding Study.  (Unpublished study received Oct 21, 1976 under
              6F1696; CDL:095326-A)

  00040594 Shirasu,  Y.; Moritani, M.; Watanabe, K.  (1976) Oxamyl Mutagenicity
              Study  Using Bacteria.  (Unpublished study received Oct  21, 1976
              under  6F1696; prepared by  Institu4te of Environmental Toxicology
            Toxicity Dept., submitted by E.I. du Pont de Nemours & Co.,
            Inc., Wilmington, Del.; CDL:095326-C)

 00040597 Harvey,  J., Jr. (1975) Metabolism  of Oxamyl  in Tomato  Fruit.   (Un-
            published  study received Oct 21, 1976 under 6F1696;  submitted by
            E.I.  du Pont de Nemours & Co.,  Inc., Wilmington, Del.; CDL:
            095326-F)

 00040603 E.I. du Pont  de Nemours & Company,  Incorporated  (1976)  Results of
            Tests on the Amount of Residue  Remaining  on Treated  Crops.   (Un-
            published  study received Oct 21, 1976 under 6F1696;  CDL:-
            095326-N)

 00040605 Han, J.C.Y.;  Harvey, J., Jr.  (1975) Characterization  of 14C-Harvest
            Residues in Potato Tubers.   (Unpublished  study received  Oct 30,
            1975  under 6F1695; submitted by E.I. du Pont  de Nemours  & Co.,
            Inc., Wilmington, Del.; CDL:095227-B)

00040607 E.I. du  Pont  de Nemours & Company,  Incorporated  (1975)  Oxarayl Resi-
            due  Data—Potatoes  (Tubers).   (Unpublished "study received Oct
            30,  1975 under 6F1695; CDL:095227-D)

00048060 E.I. du  Pont  de Nemours & Company,  Incorporated  (1975)  Results  of
            Tests on the Amount of Residu^  Remai.'ng on Treated Crops: "Oxa-
            myl |  .   (Unpublished study rec •'".ved  C .t 30,  1975 under 6F1696;
            CDL:095228-B)
                                                      150

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ati
                     OFFICE  OF  PESTICIDE  PROGRAMS

                  REGISTRATION  STANDARD BIBLIOGRAPHY

               Considered  to be Part  of the  Data Base Supporting
               Registrations Under  the Oxamyl  Standard
MR ID
          CITATION
         E-I-  du Pont  de  Nemours  and  Company,  Incorporated  (1976)  Data Sup-
            porting  the Use  of  Vydate-(R)\  L  Oxamyl  Insecticide/Nematicide
            on Celery.   (Unpublished  study  received  Oct  27,  1976  under 352-
            372; CDL:226801-A)

00063009  Hoberman, A.M.;  Mossburg,  P.A.;  Wolfe,  G.W.;  et  al.  (1980) Teratol-
            ogy Study  in  Rabbits: Oxamyl: Project  No.  201-545;  HLO-0801-80.
            Final rept.   (Unpublished study received Nov  21,  1980 under  352-
            371; prepared by Hazleton Laboratories America,  Inc.,  submitted
            by E.I.  du Pont  de  Nemours &  Co.,  Wilmington,  Del.; CDL:
            099754-B)

00063011  Da-shiell, O.L.;  Hinckle,  L.  (1980) Oral LD50 Test  in Rats — EPA  Pro-
            posed- Guidelines:  Haskell Laboratory Report  No.  775-80.   (Unpub-
            lished study  received Nov 21,  1980 under 352-371; submitted  by
            E.I.  du  Pont  de  Nemours & Co.,  Wilmington,  Del.;  CDL:099754-D)
00063012 Dulka,  J.J.;  Julius,  A.J.  (1978)
           Oxamyl  in  Soil.   (Unpublished
           352-371; submitted by E.I.  du
           Del.; CDL:099754-E)
                                  Microbial Degradation
                                  study received Nov 21,
                                  Pont de Nemours & Co.,
of 1—14\C-
 1980 under
 Wilmington,
30063016 E.I. du  Pont  de Nemours & Company (1980)  Residue Summary: Oxamyl —
           Pears.   (Unpublished study received Nov 21,  1980 under 352-371;
           CDL:099754-L)

D0066902 Tayfun,  F.O.  (1969)  Acute Dust Inhalation Toxicity: Haskell Labora-
           tory  Report  No.  280-69.   (Unpublished study received Nov 29,
           1972  under 3G1316;  submitted by E.I. du Pont de Nemours & Co.,
           Inc., Wilmington,  Del.;  CDL:092249-N)

0066903 Tayfun,  F.O.  (1969)  One-hour Inhalation Toxicity: Haskell Labora-
           tory  Report  No.  281-69.   (Unpublished study received Nov 29,
           1972  under 3G1316;  submitted by E.I. du Pont de Nemours & Co.,
           Inc.,  Wilmington,  Del.;  CDL:092249-0)
                                                        15

-------
                     OFFICE OF PESTICIDE PROGRAMS

                  REGISTRATION STANDARD BIBLIOGRAPHY

     Citations Considered to be Part of the Data Base Supporting
               Registrations Under the Oxamyl Standard


MRID      CITATION

00066914 Knott, W.B.; Johnston, C.D. (1969) Insecticide 1410: Evaluation of
            Acute LC\50- for Bluegill Sunfish.   (Unpublished study received
            Nov 29, 1972 under 3G1316; prepared by Woodard Research Corp.,
            submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
            Del.; CDL:092249-AA)

00066916 Knott, W.B.; Johnston, C.D. (1969) Insecticide 1410: Evaluation
            of Acute LC\50- for Rainbow Trout.   (Unpublished study received
            Nov 29, 1972 under 3G1316; prepared by Woodard Research Corp.,
            submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
            Del.; CDL:092249-AC)

00067234 E.I. du Pont de Nemours & Company  (1980) Data Supporting Special
            Local Need Labeling for Use of Vydate-(R)\ L Insecticide/Nemati-
            cide on Apples  in the State of Illinois.   (Unpublished study
            received Jul 24, 1980 under IL 80/6; submitted by state of
            Illinois for du Pont; CDL:243033-A)

00076813 Adamik, E.R.; Criswell,  M.K.; Mahler, S.C.;  et al.  (1981) Long  Ten
            Feeding Study in Mice with Oxamyl: Project No. WIL-77033; HLO-
            252-81.  (Unpublished study received May  29, 1981 under 352-372
            prepared by WIL Research Laboratories,  Inc., submitted by E.I.
            du Pont de Nemours & Co., Wilmington, Del.; CDL:070136-A;
            070137; 070138; 070139; 070140; 070141; 070142;  070143)

00081618 Interregional Research Project Number 4  (1981) Summary of Residue
            Data: A0xamyl/Eggplant Field Trials!.   (Compilation;  unpublishe
            study received Sep 4, 1981 under  1E2566;  CDL:070295-A)

00083522 E.I. du Pont de Nemours & Company  (1978) Results  of Tests  on the
            Amount of Residue Remaining on Treated  Crops:  A0xamyl|.   (Unpub
            lished study received Jul 30,  1979 under  352-371;  CDL:'098845-G)

00083524 Zahnow, E.W. (1978) Oxamyl-chicken and  Egg Study.   (Unpublished
            study received Jul 30, 1978 under 352-371;  submitted by E.I. du
            Pont de Nemours & Co., Wilmington,  Del.;  CDL:09°S45-K)
                                                       152

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                    OFFICE OF PESTICIDE PROGRAMS

                  REGISTRATION STANDARD BIBLIOGRAPHY

          ions  Considered to be Part of the Data Base Supporting
               Registrations Under the Oxamyl Standard
00083525 Harvey, j., Jr-. Han> j.c.Y.; Reiser,  R.W.  (1978)  Metabolism  of
           oxamyl  in plants.  Journal of Agricultural and  Food Chemistry
           26 ( 3 ): 529-536 .   ( Also-In-unpubl ished submission received Jul  30,
           1979 under 352-371; submitted by E.I.  du Pont de Nemours & Co.,
           Wilmington, Del.; CDL: 098845-L)

00084889 E.I. du Pont de  Nemours & Company (1980)  -Residues of Oxamyl  on
           Tomatoes | .  (Compilation; unpublished study received Oct 15,
           1981 under 352-372; CDL: 2346106-A)

00094660 Dudeck, S.; Bristol, K.L.  (1981) Final Report: Single-dose Oral
           Toxicity Study in Mallard Ducks: Project No. 201-543.   (Unpub-
           lished study  received Jan 29, 1982 under 352-372; prepared by
           Hazleton Laboratories America, Inc., submitted by E.I.  du Pont
           de Nemours &  Co., Inc., Wilmington, Del.; CDL: 246726-A)

00094664 Muska, C.F.; Brittelli, M.R.;' Hall, C.L.  (1981) Chronic  Toxicity
           of Oxamyl to-Daphnia magna-:: Haskell Laboratory  Report No. 580-
           81.  (Unpublished study received Jan 29,  1982  under  352-372;
           submitted by  E.I. du Pont de  Nemours &  Co.,  Inc.,  Wilmington,
           Del . ; CDL: 246726-E)

00113339 E.I.  du Pont de  Nemours & Co.,  Inc.  (1977)  A Determination of Oxamyl
           Residues on Treated Crops | .   (Compilation;  unpublished study
           received Mar  17, 1977 under  352-372; CDL: 096042-A)

10113341 E.I.  du Pont de  Nemours & Co.,  Inc.  (1976). Results of Tests  on  the
           Amount of Residue Remaining  on Treated  Crops:  ^Oxamyl |  .  (Com-
           pilation; unpublished study  received Jan 17,  1977 under 352-
           372; CDLC095720-A)

0113343  E.I.  du Pont de Nemours & Co.,  Inc.  (1976)  Results of Tests on the
           Amount of Residue Remaining  on Treated  Crops:  "Oxamyl | .  (Com-
           pilation; unpublished study  received Jan 18,  1977 under 352-372;
           CDL:095719-A)

0113357  E.T.  du Pont de Nemours & Co.,  Inc.  (1974)  "Residues of DPX 1410
           in Peanuts  and Various Other  Crops | .   (Compilation; unpublished
           study received Aug 1, 1974 under 3G1316;  CDL: 094669-B)

0113370  E.I-  du Pont de Nemours & Co.,  Inc.  (1974)  Residue Data:  "Oxamyl | .
           (Compilation;  unpublished study received Oct 31,  1974  under
           3G1316;  CDL: 095-009-C)
                                                        153

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 MRID
                OFFICE OF PESTICIDE  PROGRAMS

             REGISTRATION STANDARD BIBLIOGRAPHY

Citations Considered to be Part  of the  Data Base Supporting
          Registrations Under the Oxamyl  Standard


     CITATION
 00113373 E.I. du Pont de Nemours & Co., Inc. (1972) Results of Tests on the
            Amount of Residue Remaining on Treated Crops: A0xamyl|.   (Compi-
            lation; unpublished study received Dec 1, 1972 under 3G1316;
            CDL:095011-L)

 00113376 E.I. du Pont de Nemours & Co., Inc. (1973) Vydate Oxamyl Insecti-
            cide/Nematicide: Fish Residue Study-   (Compilation; unpublished
            study received Aug 1, 1973 under 352-371; CDL:009019-A)

 001133,80 E.I. du Pont de Nemours & Co., Inc. (1977) Results of Tests on the
            Amount of Residue Remaining on Treated Crops: ^Oxamyl|.   (Compi-
            lation; unpublished study received Aug 17, 1977 under 352-372;
            CDL:096320-C)

 00113387 E.I. du Pont' de Nemours & Co., Inc. (1979) Results of Tests on
            the Amount of Residue Remaining on Treated Crops:  ^Oxamyl|.
            (Compilation; unpublished study received Sep  14,  1979 under
            352-372; CDL:098958-A)

 00113389 E.I. du Pont de Nemours & Co., Inc. (1978) Results of Tests on the
            Amount of Residue Remaining on Treated Crops: ^Oxamyl|.  (Compi-
            lation; unpublished study received Nov 17, 1978 under 9E2148;
            CDL:097629-A; 098399)

 00113410 E.I. du Pont de Nemours & Co., Inc. (1976)  AStudy: Vydate  L Residue
            on Celery|.  (Compilation; unpublished study  received Jul  28,
            1978 under 352-372; CDL:234575-A)

00113412 Heitmuller, T.  (1978) Acute Toxicity of H-11738  to Grass Shrimp
            ...: Report No. BP-78-4-066.   (Unpublished study  received  Sep
            13, 1978 under 352-EX-89; prepared by  EG  & G,  Bionomics,  submit-
            ted by E.I. du Pont de Nemours  & Co.,  Inc.,  Wilmington, DE; CDL:
            235326-A)


00113414 Hollister, T.  (1978) Acute Toxicity of H-11738  to Embryos  of East-
            ern Oysters  ...: Report No. BP-78-4-067.   (Unpublished  study
            received Sep 13, 1978 under 352-EX-89;  prepared by EG & G, Bio-
            nomics, submitted by E.I. du  Pont de  Nemours & Co.,  Inc.,  Wil-
            mington, DE; CDL:235326-C)
                                                             154

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                     OFFICE OF PESTICIDE PROGRAMS

                  REGISTRATION STANDARD BIBLIOGRAPHY

     Citations  Considered to be Part  of the Data Base Supporting
               Registrations Under  the Oxamyl Standard


MRID       CITATION

00113419 Hawaii  (1978)  -Study:  Vydate Residues on Tomatoes|.   (Unpublished
            study  received Oct 29,  1979 under HI 79/8; CDL:241281-B)

00116609 Roberts,  N.;  Phillips,  C.; Chanter, D.; et al.  (1982) The Effects
            of  Dietary Inclusion of Oxamyl on Reproduction in the Mallard
            Duck:  Report  No.  DPT 106WL/81992.  (Unpublished study received
            Oct  3,  1982 under 352-372; prepared by Huntingdon Research
            Centre,  Eng.,  submitted by E.I. du Pont de Nemours & Co., Inc.,
            Wilmington, DE;  CDL:248464-A)

00116610 Roberts,  N.;  Phillips,  c.; Chanter, D.; et al.  (1982) The Effects
            of  Dietary Inclusion of Oxamyl on Reproduction in the Bobwhite-
            Quail:  DPT 107 WL/8261.   (Unpublished study  received Oct 3, 1982
            under  352-372; prepared by Huntingdon Research Centre, Eng.,
            submitted  by  E.I.  du Pont de Nemours & Co.,  Inc., Wilmington,
            DE;  CDL:248465-A)

00126690 Interregional Research Project No. 4  (1983)  Results  of Tests on
            the  Amount of Residue Remaining on Treated Crops: -Oxamyl|.
            (Compilation;  unpublished study received  Mar 28,  1983 under
            352-372; CDL:071504-A)

10129354 E.I. du Pont  de  Nemours &  Co., Inc.  (1983) Du Pont Vydate  L Insec-
            ticide/Nematicide:  Bananas: Residue Data.   (Compilation;  unpub-
            lished  study  received May 23,  1983 under  3F2833;  CDL:071622-A)

10134709 Harvey, J.  (1973)  Additional Studies on the  Metabolism and Biode-
           gradation  of  Oxamyl in  Plants.   (Unpublished study  received
            1973 under 3G1316;  submitted by E.I. du Pont de Nemours & Co.,
           Inc., Wilmington,  DE; CDL:092126-B)

0138996 Interregional Research Project No.  4  (1983)  The Results  of Tests on
           the Amount of  Oxamyl Residues  Remaining  in or on  Peppers, In-
           cluding a  Description of  the Analytical Method Used.   (Compila-
           tion; unpublished study received  Feb  16,  1984 under 352-372;
           CDL:072368-A)

1141395 Chrzanowski,  R.  (1984)  Soil  Column  Absorption Studies with Vydate
           Oxamyl Insecticide/Nematicide.   Unpublished study prepared by
           E.I. du Pont de  Nemours & Co.,  Inc.   11 p.
                                                                  155

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                     OFFICE OF  PESTICIDE PROGRAMS

                  REGISTRATION  STANDARD BIBLIOGRAPHY

     Citations Considered to be Part of the Data Base Supporting
               Registrations Under the Oxamyl Standard


MRID      CITATION

00142126 E.I.du Pont de Nemours and Co., Inc. (1984) Du Pont Vydate  L
            Insecticide/Nematicide  [Use  on Bananas].   Unpublished
            compilation. 90 p.

00143312 E.I. du Pont de Nemours & Co., Inc.  (19??) Oxamyl/DMCF Residue
            Analyses - Cucurbits.  Unpublished study.  79 p.

00143315 Dickhaus, S.; Heisler,  E.  (1980) Irritant Effects of Molinate
            on Rabbit Eye:  1-3-258-80.   Unpublished study prepared  by
            Pharmatox.  10 p.

00147614  E.  I.  Du Pont  De  Nemours and Company (1980)  Residue  Data
            Supporting the  use  of Vydate  L Insecticide/Nematicide  on
            Celery.   Unpublished study.   10 p.

00149231  Mclntosh,  C.;  Jenkins, J.:  Burgoyne,  D.;  et  al. (1984)   A
            Two- Year Field Study to Determine the Fate of Oxamyl in
            Soil during  Flood Irrigation.   Unpublished study prepared
            by E.I.  DuPont de Nemours and Co. Inc.   14 p.

00154748  Rao, P.; Wheeler,  W.;  Dickson, D.  (1983)  Sorption, Leaching,
            and Degradation of  Nematicides  (Oxamyl  and Phenamiphos) in
            Three  Southeastern U.S.  Soils:  1982  Short-term  PIAP
            Project:  Final Report (Report # 2).   Unpublished  study
            prepared by University of Florida.   12 p.

00163605 E.  I.du Pont de Nemours & Co., Inc.  (1986?)  Du Pont "Vydate" L
             Insecticide/Nematicide:   [Foliar  Dissipation  Study].
             Unpublished compilation.   99  p.

00163606 Du  Pont Canada Inc. (1982) Vydate  Oxamyl  Insecticide/
             Nematicide:  Applicator Exposure  Study.   Unpublished
             study.   5 p.

05001991 Stevenson,  J.H.  (1?""8)  The acute toxicity of unformulated
            pesticides  to  -orker honey  bees  (:Apis  melliferaLQ .
            Plant Pathology 27 (1): 38-40.,
                                                      156

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   APPENDIX  V
FORMS APPENDICES

-------
                                                                       OMB Aaarov* No. XOO-O46S
                 FIFHA SECTION 3• rop«n4a>f «
                                            by m« f IFHA
                                                                  31CK2JI8)
                                                                                       m tru f
      O I. I «* Mtwwt tra in « a»«> !!••• m mtftj avt loflrnif rrquirvntnu. It D>« tnt 9 OM QMKICJU tfouo. OECO
                    iMf Proyvnrat, I mdo» Ox protocaa rtvit I will u«:
           Attach  separate  page with a  list  of  the data requirements  your  company
           agrees  to  satisfy.
G 2. I tov« «it>r*4 into *i
     r*quirvn«ia. Th«
                                  mrOl tm m man affm rt^arrvra unrter FIFRA MCCWMI 3(C)(Z)(3)(fl te atafv itw Idlowus
                                        prvtocMk •* b* aibmirtBd to EPA fry:
   NAME OF OTH€fl REGISTWA^T
                                   Attach  list of  data  requirements
      LJ 2.  I «ndo«t i twn&mt "C*rofcatjo« tf Atmrl o« • nm twUbt* la
                                                                                             nm product]):
     Qi  i
                                 •ItfMf
                                                    (TW apeoa • net
                                                                                        (VI
HEGlSTRAXT-J
                                                 SIGMA FURS
                                                                                                OATC
EPA
             I II
                                                                                       158

-------
CERTIFICATION OF ATTEMPT TO ENTER
_ m ... ^ INT° AN AGREEMENT WITH OTHER REGISTRANTS
(To&Mitfy. CWT//V41L fourinmtf FOR DEVELOPMENT OF DATA
1. 1 tm duly •uttxxu.d to "ixmm *. Moving finnU) -no .0, ajb^ct to *, recuire-
m^itiof . Not.c» und»r FIFRA S*rT«o 3irtloo jod tutvnit th« d*ti u requirtd by th*t Notica. if rwceiury. However, my firm would prefer to enter
mto an agreement with on« of more otHer reqirtrjntj to develop jointly, or to tfijre in the colt of developing, the following required
itemi or dat«:
   3.  My firm n*i oHerrd m writing to enter into «jd< tn »o/»ement. Coo««i of the oHtM we in«cn»d. Thit ofltr wtt irrrvooole *nd mcludid in off«f 10 b«
      oound 6y  in irbitfltion dfrmon under FIFRA Section 3(c)(2)(8)(iii) A finel igrtemmt or c dJta ntied .n pi.^r}(yi (2)  Joove  o iccorcUrvie «.t", tne Not,^  :  uort.ruand SPA w,n o'ompdy .
      e  .'..-,,  my  r.-m  -..uii *j'J.n,t <3H» lu J»0'd  luirenvon of  ti ^ntflfontM  ,nc!er  PlFaa, $.r-.mn :(c((2;(B>  ITh,\ vit
    >ice^ no; r'alv  to ioolican.i fcx n*w prodoctl.)  I give £PA ppm.si.on  to o.icio*- tr>,i itatemeni upon r,:qu«i
|  ' "to s.
                                                                                                                     59

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                            PRODUCT SPECIFIC DATA REPORT
EPA Reg.  No.
Date
Guidance  Document for
Registration
Guideline No.
§158.120
PRODUCT
CHEMISTRY
61-1
61-2
61-3
62-1
62-2
62-3
63-2
63-3
63-4
63-5
63-6
63-7
63-8
63-9
63-10
63-11
63-12
1
Name of Test

Identity of
ingredients
.statement of
composition
Discussion of
formation of
ingredients
Preliminary
analysis
Certification of
limits
Analytical methods
for enforcement
limits
Color
Physical state
Odor
Melting point
Boiling point
Density, bulk-
density, or
specific gravity
Solubility
Vapor pressure
Dissociation
constant
Octanol/water
partition
coefficient
pH
Test not
required
for my
product
listed
above
(cneck
below)


















I am complying with
data requirements bv
Citing MRID
Number or
EPA Accession
Number


















Suonit-
ting
Data
(At-
tached)


















(For EPA Use OnJ
Accession Numbe:
Assigned


















                                                       160

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                                             CMB Approval No. 2070-0057
                                             Expiration Date 11/30/89
                          GENERIC DATA EXEMPTION  STATEMENT

 EPA Product Registration Number:	

 Registrant's Name and Address:
     As an authorize.-! representative 3t  the registrant of  the oroduct identified
 aoove, I cert it/ tnat:

     (1)  I have read and am familiar with  the  terms of  the Notice from EPA dated
               concerning a requirement  for submission of  "generic" data on tne
 active ingredient 	 named under  FIFRA Section 3(c)(2)(B)

     (2)  .My firm requests that EPA not suspend the  registration of our product,
 despite our lack of intent to submit the generic  data  in question, on the grounds
 that the product contains the active ingredient solely as  the  result  of the
 incorporation into the product of another product which contains  that active
 ingredient, which is registered under FIFRA Section  3,  and which  is purchased by
 us from another producer.

     (3)  An accurate Confidental Statement of  Formula(CSF) for the above-identifled
 product is attached to this statement.  That tormula  statement indicates, by
 company name,  registration number, and product name,  the source of the subject
 active ingredient in my firm's product, or

 The CSF dated 	 on file with EPA is complete,  current and accurate and
 contains the information requested on the current CSF Form No. 8570-4.  The
 registered source(s) of Che above named active ingredient  in my product(s)  is/are
 	 and their registration number(s)  is/are  	  .

     My firm will apply for an amendment to the registration prior  to changing
 the source of  the active ingredient in our product.

     (4)   I understand,  and agree on behalf of my firm, that  if at any time  any
 portion of this Statement is no longer true, or  if my  firm fails to comply  with
 the undertakings made in this Statement, my firm's product's  registration may be
 suspended  under FIFRA Section 3(c)(2)(B).

     (5)  I  further understand that if my firm  is granted a generic data exemption
 for the  product, my firm relies on the efforts of other persons  to provide the
Agency with the required generic data.   It the registrant(s)  who have committed
 to  generate and submit the required data tail  to take  appropriate steps to meet
 requirements or are no longer in ccnpliance with this  Notice's data  requirements,
 the Agency  will consider that both they  and my firm are not in compliance  and
will normally  initiate proceedings to suspend  the registrations  of my  firm's
product(s)  and  their product(s), unless  my  firm  commit^ to submit  and submits
the required data in the specified tune  frame.   I undf-tand  that,  in such cases,
the Agency  generally will not grant a  time  extension  tor  submitting  the data.
Registrant's authorized representative:
                                                (Signature!

Dated: 	
EPA Form  857U-27
                                                  (Typed!

                                               161

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United States
Environmental Protaetion
Agency
O«ic*of
Pacttcidei and Toxic Sutwtanc
Washington DC 20460
                         June 1987
Pesticides
Guidance for the
Reregistration of
Pesticide Products
Containing  Oxamyl
as the Active Ingredient


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