United States
               BOl
                          EPA-560/11-90-023
                            •80

Volatile Corrosion Inhibitors
and Boiler Water Additives:
Potential for Nitrosamine Formation

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This document  is available through the National
Technical Information Service (NTIS), Springfield,
Virginia 22161, Telephone No.  (703) 557-4650.

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        CHEMICAL TECHNOLOGY AND ECONOMICS IN
             ENVIRONMENTAL PERSPECTIVES

 TASK III - VOLATILE CORROSION INHIBITORS AND BOILER
WATER ADDITIVES:   POTENTIAL FOR NITROSAMINE FORMATION

                         by

                  Alfred F. Meiners
                  Howard Gadberry
                  Bonnie L. Carson
                  Harold P. Owens
                  Thomas W. Lapp
                    FINAL REPORT
                    May 15, 1980

             EPA Contract No. 68-01-3896
              MRI Project No. 444l-T(3)
                         For

           Environmental Protection Agency
      Office of Pesticides and Toxic Substances
                 401 M Street, S.W.
               Washington, D.C.  20460

              Attn:  Mr. Roman Kuchkuda
                     Project Officer

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                                  DISCLAIMER
     This report has been reviewed by the Office of Toxic Substances,  U.S.
Environmental Protection Agency, and approved for publication.   Approval does
not signify that the contents necessarily reflect the views and policies of
the U.S. Environmental Protection Agency, nor does mention of trade names or
commercial products constitute endorsement or recommendation for use.

     The report was prepared as part of a preliminary evaluation by EPA and
should not be construed as presenting final Agency judgement concerning the
subject chemicals.

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                                    PREFACE
     This report presents the results of a study to develop information con-
cerning volatile corrosion inhibitors.

     This study was performed by Midwest Research Institute, as Task III under
Contract No. 68-01-3896 for the Office of Pesticides and Toxic Substances of
the U.S. Environmental Protection Agency.  The project officer for this study
was Mr. Roman Kuchkuda.  Mr. Charles Auer was the EPA Technical Officer.  Princi-
pal Midwest Research Institute contributors to this study included:   Dr. Alfred F.
Meiners (Task Leader), Principal Chemist; Mr. Howard Gadberry, Senior Advisor
for Technology; Ms. Bonnie L. Carson, Associate Chemist; Mr. Harold P.  Owens,
Associate Industrial Chemist; Ms. Mary Simister, Social Analyst; Ms. Joy McCann,
Junior Scientist; and Mr. Fred Hopkins, Assistant Scientist.  Dr. Thomas W.
Lapp is the project leader for this contract, under the supervision of
Dr. Edward W. Lawless, Chemical Impact Assessment Section.
Approved for:

MIDWEST RESEARCH INSTITUTE
B. W. Macy, Acting Director
Center for Technoeconomic Analysi
                                     iii

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                                 CONTENTS

Preface	   iii
Figures	    iv
Tables	    iv
     1.  Introduction and Objectives .  .	  .     1
     2.  Summary and Conclusions 	     3
               Volatile corrosion inhibitors 	     3
               Volatile amines in boiler systems .... 	     6
     3.  Volatile Corrosion Inhibitors 	    11
               Definition of VCIs and their function 	    n
               Compounds used as VCIs	    12
               Uses of VCIs	    17
               Market information	    19
               Theories of the mode of action of VCIs	    21
               Potential nitrosamine formation in dichan and
                 related compounds 	    23
               Potential for adverse environmental effects ....    24
     4.  Volatile Amines in Boiler Systems 	    27
               Boiler water treatment practices	    27
               Present status of usage of amines in boilers  ...    34
               Market information	    35
               Potential for nitrosamine formation in boilers.   .  .    37

References	    41
Appendices

     A.  Physical properties of VCIs, boiler water amines and
            related compounds 	    47
     B.  The market for amines and corrosion inhibitors	    75
     C.  Review of possible nitrosamine formation reactions of
            VCIs and boiler water amines	    81
     D.  Market information on selected compounds used  for
            corrosion inhibition	    87

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                                 FIGURES
Number                                                           Page

 3-1      Thermal Stability of Dichan	   23


                                 TABLES


Number                                                           Page

 2-1      U.S. Market for VCI Products, 1978	 .    4

 2-2      Estimated Consumption of Neutralizing and Filming
            Amines  	    7

 3-1      Major Uses of Benzotriazole Compounds ........   16

 3-2      U.S. Market for VCI Products, 1978	 .   20

 4-1      Recommended Characteristics of Boiler Feedwater ...   29

 4-2      Recommended Characteristics of Boiler Water 	   30

 4-3      Quantities of Amines Required to Obtain Particular
            pH Values in Pure Water	   33

 4-4      Estimated Consumption of Selected Amines as Boiler
            Water Additives	   36

 B-l      Estimated use of Vapor Phase Corrosion Inhibitors
            by Industry	   76

 B-2      Estimated U.S. Sales of Chemicals and Formulated
            Chemical Specialities in Refining, Gas Conditioning
            and Pipeline Transmission, 1977—  	   78
 B-3      Comparison of Nace and Kline Surveys Concerning
            Corrosion Inhibitors (Millions of Dollars)	
79

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                                   SECTION 1

                          INTRODUCTION AND OBJECTIVES
     The Environmental Protection Agency (EPA) has expressed concern that po-
tentially carcinogenic nitrosamines may be formed from the use of secondary
amines* as components of volatile corrosion inhibitors (VCIs).  Recent reports
have shown that nitrosamines are formed when secondary amines are incorporated
into plastic wrapping materials for metal products.   Nitrosamines have also
been detected in commercial samples of similar wrapping materials.  Recent re-
ports have stated that substitutes are being developed for these products be-
cause of the nitrosamine problems.  Relatively large quantities of volatile
amines are also known to be used as boiler water additives.   Another concern
was the possible use of amines in boilers with nitrate or nitrite salts,
thereby resulting in the potential for nitrosamine formation.

     This study was initiated to provide information concerning the materials
which are used for these purposes, the quantities which are consumed, and the
possibilities for nitrosamine formation.

     According to most industry sources, the term "volatile corrosion inhibi-
tor" refers to compounds that can volatilize and protect metal surfaces ex-
posed to air or other corrosive gases.  It might be more accurate to describe
VCI as "vapor phase corrosion inhibitors."  Relatively few compounds can func-
tion as true VCIs, and almost all of these are secondary amine derivatives;
however, hundreds of other compounds (including a wide variety of amines) are
used in corrosion protection applications where a degree of volatility may be
desirable.

     Chemicals which are commonly used as VCIs are not normally used as boiler
water additives.  A number of secondary amines and other volatile compounds
are employed as neutralizing agents and film-forming materials in the treat-
ment of boiler water.  Thus, the primary function of the boiler water amines
is distinctly different from VCIs.  The volatility of the boiler water amines,
specifically their ability to steam distill, simply allows them to be intro-
duced into the boiler and transferred through the system to the area which re-
quires corrosion protection, i.e., the area where the steam condenses to give
a liquid-metal interface.

     This report is divided into four major sections.  Section 1 presents an
introduction to the report and outlines the program objectives.  Section 2
     A secondary amine has two organic groups and one hydrogen atom attached
       to the nitrogen atom (

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contains a summary and conclusions.  Section 3 provides data concerning VCIs.
Section 4 presents a discussion of the use of volatile amines in boiler sys-
tems.  There are four appendices:  Appendix A contains descriptions of the
physical properties of VCIs, boiler water amines,  and related compounds; Ap-
pendix B reviews the overall market for amines as  VCIs; Appendix C reviews
possible nitrosamine formation reactions of VCIs and boiler water amines; and
Appendix D contains available market information on VCIs, boiler water amines,
and related products.  This information was obtained from nonconfidential in-
formation submitted to EPA by manufacturers and importers as of January 1979.

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                                   SECTION 2

                            SUMMARY AND CONCLUSIONS
     A summary of the results obtained in this study is presented in this
two-part section.  The first part summarizes the investigation of VCIs,  and
the second part summarizes the study of the use of amines in boiler systems.

VOLATILE CORROSION INHIBITORS

     The semantics of VCIs is not totally clear, but the term is generally
recognized to mean a chemical substance that by virtue of its volatility at
room temperature reaches a metal surface in need of corrosion protection.

     Although a large number of volatile products have been used as VCIs in
the past, the major products at present are dicyclohexylammonium nitrite
(Dichan), "nonnitrite" substitutes for Dichan (in which the nitrite has  been
replaced), and benzotriazole.
     Dichan (Dicyclohexylammonium       "Nonnitrite" Dichan substitute
       nitrite)                           (substituted benzoate salt of
                                          dicyclohexylamine )
     Benzotriazole


     Industry sources indicate that Dichan has recently been substantially re-
placed by nonnitrite VCIs.  The structures of these products are proprietary,
but apparently they are salts of dicyclohexylamine, probably substituted ben-
zoic acid salts in which the substituted benzoate ion has replaced the nitrite
ion of Dichan.

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     Benzotriazole is a VCI which inhibits the corrosion of copper.  As a VCI,
 it is  used almost exclusively in impregnated paper.  Benzotriazole has many
 applications other than as a corrosion inhibitor; most of the production quan-
 tities  in the United States are probably used in photographic processes.

 Market  Information

     The present market for VCI products is approximately 310,000 kg/year
 (Table  2-1) and appears to have remained at this level for the last few years.
 The products have been on the market in the United States for at least 25
 years  but have never substantially exceeded the present volume.
                TABLE  2-1.  U.S. MARKET  FOR VCI PRODUCTS, 1978
                                   Amount of VCI used (x 10^ kg/yr)
                                Impregnated paper
                               and other wrapping          All other VCI
      Compounds                     materials               applications

Dichan (dicyclohexyl-
  aramonium nitrite                      95                       14

Benzotriazole                           30                        0

"Nonnitrite" VCIs                      170                        2

     Totals                            295                       16
Source:  MRI estimates•
 Uses

      Over  90% of  the  use  of  these products  is  in the preparation of  impreg-
 nated paper  and other wrapping materials.   Impregnated paper is widely used
 for the  protection  of small  metallic  objects during storage and shipment.
 Impregnated  paper is  also used to protect relatively large items, for example,
 stacks of  black plate (untinned  steel)  and  tin plate used in the manufacture
 of cans.   A  relatively new VCI product  on the  market is an impregnated plastic
 film  for wrapping.

      VCIs  are also  used in applications in  which the solid product is placed
 within the item it  is designed to protect.  Many "devices" have been developed

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for this purpose.  Formerly, the products were used to protect equipment
within the holds of cargo vessels during shipment, but this application has
apparently greatly declined or even disappeared.

Mechanism of Action

     Although the mechanism of VCI inhibition has not been studied in detail,
the protection is apparently due to adsorption of a film on the metal surface.
This film protects against the corrosive effects of water and/or oxygen.

Nitrosamine Formation Potential

     Dichan, the nitrite salt of dicyclohexylamine, can apparently be con-
verted under ambient conditions to the corresponding nitrosamine.  The com-
mercial product can contain significant concentrations (1 ppm) of the nitros-
amine .
                    NH    NO  	,,    N—J \N-NO  +  HO
            Dichan                      N-Nitrosodicyclohexylamine

The nonnitrite VCJs-are less likely to be converted to n i.trosami ncs l>o< ;itise
the nitrite salt, a major nitrosatirig reagent, is not available.  However,
other secondary amines can be nitrosated under "environmental" conditions via
a number of mechanisms, and the nonnitrite VCIs would be expected to be read-
ily susceptible.  (See Nitrosamine Formation Reactions, Appendix C.)

Potential for Adverse Environmental Effects

     A large number of people come into contact with VCIs because of their use
in the wrapping of small metallic items.  Over 20 million individual items are
wrapped each year in VCI paper (MRI estimate) and these packages ultimately
expose the user to VCI vapor.  Production workers involved in the manufacture
of VCIs and VCI-impregnated paper are also exposed.  Two cases of nitrosamine
detection in VCI wrapping material have been reported.  In one, N-nitroso-
N,N-dibutylamine was found at an estimated concentration of 100 ppm in an un-
identified commercial film.  The same researchers prepared a VCI polyethylene
film and found it to contain 90 ppm nitrosomorpholine.

     Dichan enters the atmosphere as a VCI, but it probably is not a long-
lived constituent because of its susceptibility to photolysis.  However, no
reports were found concerning the nature of its photolytic decomposition
products.

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     No reports have been found concerning the environmental effects of sta-
bility in the environment of nonnitrite Dichan substitutes.   Dichan substi-
tutes can probably be nitrosated in the environment via a number of mecha-
nisms.

Benzotriazole--
     Benzotriazole is likely to be quite stable and persistent in the environ-
ment.  However, the perceived potential for environmental contamination has
been small, and the attention paid to it has been negligible.  Benzotriazole
apparently cannot be converted to the N-nitroso product.

VOLATILE AMINES IN BOILER SYSTEMS

     A number of amines are employed in the treatment of boiler water; the
amines are primarily used as neutralizing agents and film-forming materials.
Thus, their primary function in these applications is distinctly different
from that of true VCIs.  Their volatility (or more exactly,  their ability to
steam distill) simply allows them to be introduced into the  boiler and trans-
ferred through the system to the area which requires corrosion protection,
namely, the area where the steam condenses to form a liquid-metal interface.

     The most widely used neutralizing amines are cyclohexylamine, morpholine,
2-diethylaminoethanol, methylpropylamine (relatively new), and a few others.
The total annual market is estimated to be 6,500 to 7,800 metric tons in 1978
(see Table 2-2).

     Octadecylamine represents about 95% of the film-forming amine market, es-
timated to be about 5 million pounds in 1978.

Potential for Nitrosamine Formation in Boilers

     There is no experimental evidence to indicate whether or not nitrosamines
are formed in boilers as a result of the addition of boiler  water amines.
Most boilers are operated under conditions which would (a) limit the possibil-
ity for nitrosamine formation and (b) probably result in the destruction of
any nitrosamine that might be formed.  However, under certain circumstances,
the possibility for nitrosamine formation is conceivable. These possibilities
are discussed in the following paragraphs.

Modern High-Pressure Boilers--
     Nitrates and nitrites are potential nitrosating agents  for boiler water
amines.  However, neither nitrates nor nitrites are ordinarily added to boiler
water.  For high-pressure boilers such as those used by electric utilities,
high-purity water is essential.  Purification procedures include the careful
removal of dissolved solids including nitrates, present at the 1 to 10 ppm
level in most untreated waters.  Some purification procedures require deioni-
zation of the water, and this process would remove nitrate and nitrite (as
well as other inorganic ions).  However, nitrosamines could  possibly be

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     TABLE 2-2.  ESTIMATED CONSUMPTION OF NEUTRALIZING AND FILMING AMINES
                                                Estimated
                                            1978 consumption
             Type of amine                    (metric tons)

           Neutralizing amines

           Cyclohexylamine                    3,200-3,600
           Morpholine                         1,800-2,200
           2-Diethylaminoethanol                900-1,400
           Methylpropylamine                          400
           All  others                         	200

                  Total                      6,500-7,800

           Filming amines

           Octadecylamine
           All  others

                  Total                             2,500
 Sources:   Stevens  (1978)  and MRI  estimates.


 introduced into water by resins used for deionization; samples of deionized
 water have been found to contain as high as 250 ng/liter of N-nitrosodimethyl-
 amine.

     Other potential nitrosating agents are oxides of nitrogen from air.
 Nearly complete deaeration of boiler water is ordinarily employed to remove
 undesirable dissolved oxygen and carbon dioxide.  These procedures would be
 expected to reduce greatly the concentration of dissolved nitrogen oxides in
 water.  In addition, the boilers are operated at high pH (around pH 9 or 10)
 which further limits the formation and stability of nitrosamines.   The clas-
 sical secondary amine-nitrite reaction would not be expected to occur at this
 pH although the nitrosation of amines by oxides of nitrogen could occur rap-
 idly.

     Although there are limited data on the thermal degradation of nitrosa-
mines in water, most of them are known to be thermally unstable, especially at
 temperatures in the range of 300°C.   Temperatures of 250 to 300°C  are attained
 in high-pressure boilers and sustained for relatively long periods of time.

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Thus, eventual thermal decomposition of most nitrosamines would be expected
under these conditions.  Furthermore, there is evidence that the thermal sta-
bility of some amines is greatly reduced at the high pH values found in boiler
waters.

Medium-Pressure Boilers

     Boilers operating in the pressure range of 100 to 500 psi (maximum tem-
perature about 240°C) utilize much different water treatment practice than
higher pressure boilers.  It is common for them to utilize a coordinated phos-
phate treatment system that allows operation with zero added caustic or to
maintain the desired pH with very minor caustic additions.  Sodium sulfite (or
in some cases hydrazine) may be used as an oxygen scavenger.  The use of so-
dium nitrate (at 200 to 400 ppm) to prevent caustic embrittlement is unknown
to all the boiler specialists who were consulted in this study.

     Hence, the occurrence of nitrosamines in moderate-pressure boilers is not
likely to be attributable to reactions between organic amines and other chemi-
cals intentionally added to manage these boiler water systems.

Low-Pressure Boilers

     There are hundreds of thousands of relatively small, low-pressure boilers
(25 to 200 psi, maximum temperature less than 190°C) in use for heating and
process steam generation.  The majority of these boilers are treated inter-
nally by the use of proprietary boiler water additives, which typically con-
tain phosphates, sodium sulfite, and a sludge-conditioning polymer.   None of
the boiler compound suppliers contacted were aware of any additives  which
presently contain nitrates or nitrites.  However, they did caution that some
boiler additives formulated by some of the numerous, small boiler treatment
supply firms could still incorporate nitrates and/or nitrites.  The  water used
as feed presents another possible source of nitrate.  Hence, the possibility
of reaction between neutralizing amines and nitrates or nitrites is  at least
possible in some low-pressure boiler systems.

Hot-Water Boilers

     So-called "hot-water boilers," used to circulate water to about 77°C for
heating or to generate low-pressure steam at 10 to 12 psi with 100% condensate
return,  may employ sodium nitrite as a corrosion inhibitor.  These systems are
closed and require no makeup water since losses occur only if leaks  are pres-
ent.  Chromate corrosion inhibitors are commonly used, but a combination of
sodium nitrite and borate buffer is also widely employed.  The water circulat-
ing systems do not use neutralizing or film-forming amines since the proper pH
is maintained by the buffer system.  The development of nitrosamines in hot-
water heating systems is regarded as extremely unlikely.

Reports of Nitrosamines in Steam Emission from Boilers--
     A recent report concerning a survey for N-nitroso compounds observed that
small amounts (0.002 |Jg/g) of N-nitrosomorpholine were formed in the steam

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condensate from boilers at a plant which produces chemicals for the rubber
industry (Fan, Fajen, and Rounbehler, 1978).   The authors were unable to as-
certain exactly how the nitroso compound was  formed,  but they speculated that
it was most likely formed by the transnitrosation reaction of morpholine with
N-nitrosodiphenylamine produced at this plant and was detected at various lo-
cations within the plant.  Morpholine is used at this plant as a neutralizing
amine for the boilers and as a starting material for the manufacture of a vul-
canization accelerator.  N-Nitrosomorpholine  was also detected at various lo-
cations throughout the plant in bulk samples  and in air samples.

     A total of 28 different plants were visited and sampled for N-nitrosamine
contamination.  Boiler steam condensate was sampled when nitrosamines were de-
tected at other sites in the plant.  N-Nitrosomorpholine was found in the
steam condensate at only one plant; the condensate was collected from leaks in
the steamline.  Four of the other plants used morpholine in the boilers but
had no N-nitrosomorpholine contamination.  No samples of boiler "blow down"
(the small fraction of water which is discharged from boilers for the purpose
of preventing buildup of dissolved solids) were taken at any of the plants,
and no record was made of the operating characteristics of the boilers.  The
authors observed that the nitroso compound exists as a contaminant in the mor-
pholine itself and that this fact may account for its presence in the samples
taken.  However, nitrosamine formation via a  transnitrosation reaction outside
the boiler appears to be the most likely mechanism.  Transamination can only
occur when other nitrosamine contaminants are present.

Potential for Adverse Environmental Effects

     Very little is known about the potential for environmental effects caused
by the use of amines in boiler waters.  However, over 2,700 metric tons of
secondary amines, over 5,400 metric tons of primary amines, and over 900
metric tons of tertiary amines are consumed each year in these applications.
The precise fate of these products is unknown.  Evidently, some of them escape
with steam emissions and some are discharged  as boiler blowdown.

     The discharged secondary amines would be subject to conversion to
N-nitrosamines in the environment by a number of possible mechanisms.  How-
ever, no information was found concerning the amounts or kinds of amines dis-
charged from boilers.  Also, no information was available that would conclu-
sively indicate that boiler water discharges  contain nitrosamines.

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                                   SECTION 3

                         VOLATILE CORROSION INHIBITORS
     This section presents a definition of VCIs and describes specific com-
pounds and their uses.  Information concerning the market for VCIs is pre-
sented, and theories of the mode of action are discussed.  The possibilities
for nitrosamine formation and the potential for adverse environmental effects
are also discussed.

DEFINITION OF VCIs AND THEIR FUNCTION

     Every person contacted during this study and most literature references
were in agreement about the meaning of volatile corrosion inhibitors or the
equivalent term, vapor phase corrosion inhibitors.  These terms mean a solid
substance (rarely, a substance in solution) whose vapor pressure is sufficient
in enclosed spaces to protect the metal surfaces upon which the volatilized
substance condenses, i.e., inside a package, a closed storage area, or an
automotive engine.

     Uhlig (1971) in Corrosion and Corrosion Control described VCIs as "sub-
stances of low but significant vapor pressure, the vapor of which has corro-
sion-inhibiting properties" that are used to protect steel articles during
shipping and storing.

     Volatile and nonvolatile "atmospheric corrosion inhibitors" were dis-
cussed by Putilova et al. (1960).  Nonvolatile atmospheric corrosion inhibi-
tors are generally contact inhibitors whose actions are confined to the area
where they are in contact with the metal surface.  These can be nearly any of
the compounds used in neutral aqueous solutions, especially alkali nitrites,
e.g., sodium nitrite.  Volatile atmospheric corrosion inhibitors are distin-
guished by their ability to protect while in the gaseous or vapor phase and
are, therefore, termed "vapor phase inhibitors."  Of the more than 100 dif-
ferent organic compounds tested up to about 1960, salts of amines and amino
alcohols were the best inhibitors.

     Wachter and Stillman (1952) defined a "vapor phase inhibitor" as a "com-
pound which inhibits corrosion of metal parts in the presence of water and air
(oxygen) because said compound possesses corrosion-inhibiting properties and
is capable of vaporization under conditions of use with the resultant presence
of these vapors in the vicinity of the metal."  These authors recommended the
use of a combination of two compounds, one of relatively high vapor pressure
(e.g., diisopropylammonium nitrite, Dipan) to provide instant protection and
one of lower vapor pressure (e.g., Dichan) to give prolonged protection.
                                       11

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     Products called "vapor phase rust inhibitors," especially Dipan and
Dichan, were developed by the Naval Research Laboratory for use in aqueous,
nonflammable hydraulic fluids to prevent the rusting of ferrous metals in the
vapor spaces of hydraulic systems.  Brophy et al.  (1951) described this devel-
opment of "Hydrolubes," which were polymer-thickened, aqueous hydraulic fluids
containing at least one glycol, especially ethylene glycol.  The formulations
described contained 1.6 to 1.7% Dipan.  None of the "Hydrolubes" had proved
satisfactory for prolonged use above 71°C.  Zisman et al.  (1951) patented
"Hydrolubes" in which Dipan appeared as a "vapor-phase corrosion inhibitor."*

     Wachter and Stillman (1952) patented water-glycol hydraulic fluids con-
taining amine nitrites, preferably those of secondary amines such as Dichan or
morpholine nitrite.

     In 1951, Shell Development Corporation (Harman et al., 1951) patented an
aqueous metalworking lubricant or coolant containing a mercaptan; some of these
formulations contained 0.05 to 0.5% Dipan.

     The use of amine nitrites as VCIs in the 1940's was quickly expanded to
include packaging materials because desiccants and oils were often unsatisfac-
tory for protecting military equipment and replacement parts during storage
under all climatic conditions (e.g., at subzero temperatures, the viscosity of
oils and greases prevent the operation of weapons).  Use of the VCIs eliminated
the tedious cleaning necessary when slushing compounds** were used (Baker, 1954)

COMPOUNDS USED AS VCIs

     A large number of volatile organic compounds  have been examined for use
as VCIs.  Most of the earlier published literature was by Japanese and European
scientists (Putilova et al., 1960; Singh, 1976; Takahashi, 1975).  The best
VCIs for ferrous metal were found to be salts of dialkylamines and aminoalco-
hols.  For nonferrous protection, benzotriazole and mercaptobenzothiazole were
found to be very effective corrosion and tarnish inhibitors (Cotton and Scholes,
1967).  Although a number of compounds has been patented as VCIs, only a few
have been produced for commercial use in the United States.  At the present
time, the major VCI compounds are Dichan, substitutes for Dichan, and benzo-
triazole.  Other amine salts such as dicyclohexylammonium benzoate, diisopro-
pylammonium nitrite, and cyclohexylammonium carbonate have had limited use as
VCIs in the United States.  The physical properties of these compounds and
their related nitrosamine derivatives are presented in Appendix A.
     Although the early "Hydrolubes" definitely contained the types of com-
       pounds recognized as VCIs in the literature, MRI was unable to find
       any such substance being used for that purpose today.
     Slushing compounds are petroleum-based materials,  ranging from light
       oils to semisolids, containing inorganic or organic corrosion in-
       hibitors (Campbell, 1948).
                                       12

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VCIs for Ferrous Metals

     The protection of ferrous metals represents the largest fraction (over
90%) of the VCI market.  At the present time, the market is dominated by Dichan
and closely related compounds, but other compounds are known to be effective
and have been used in the past.

Dichan--
     Dichan is one of the most effective and widely used VCI compounds for
ferrous metals.  The substance is a white, crystalline salt with a very slight
odor.  It is volatile at room temperature with a vapor pressure of 0.0001 mm
Hg at 21°C and is relatively nontoxic (Uhlig, 1971).  It is produced commer-
cially by the action of sodium nitrite on the water-soluble phosphate salt of
dicyclohexylamine.
                                 Dichan
     Dichan is more suitable than Dipan lor paper impregnation because il is
less volatile (therefore, it lasts longer) and is less soluble (Baker, 1954).

     Black and Wachter (1953) of the Shell Oil Company and the Shell Develop-
ment Company, respectively, enumerated the benefits of using Dichan (these are
also benefits of other VCIs of suitable vapor pressure):

     1.  Dichan gives excellent long-term storage protection.

     2.  Dichan will provide protection even if the container is damaged enough
to allow entry of moisture vapor.

     3.  Surfaces of assemblies that cannot be reached by other means are pro-
tected by Dichan's vapor.

     4.  The application method is clean.

     5.  Costly and tedious degreasing operations are eliminated.

     6.  Protection is maintained under widely variable ambient conditions
from arctic to tropical storage conditions.

     7.  Articles can be inspected easily.

                                       13

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Dipan--
     Dipan has been used as a VCI in the past,  but there is no evidence of its
use at the present time.  It is a rather volatile compound with a vapor pres-
sure of 0.012 mm Hg at 20°C and is therefore unsuitable for prolonged protec-
tion against atmospheric corrosion.   Tt has a flash point of 40°F and thus
would present a fire hazard.  Another reason for its lack of use as a VCI is
that although it protects steel, chromium and tin, it attacks copper, bron/c,
silver, aluminum, brass, antimony, Babbitt metal, cadmium, zinc, and lead
(Putilova et al., 1960).
                                              NO,
Cyclohexylammonium Carbonate (CHC) and Other Carbonate Salts--
     CHC is an effective VCI for ferrous metals (Lund, 1970).   It has been
produced commercially in the United States and Great Britain,  but no produc-
tion data were available.  It can be used as a powder, but tablets and CHC-
impregnated paper were available in 1964 (Anonymous, 1964).   One reason for
its current lack of use is that although it protects aluminum, zinc, chromium
plate on steel tinplate, solder and soldered joints, it i.s very corrosive to
copper, copper alloys, and magnesium (Uhlig, 1971).   It also lias a relatively
high vapor pressure of 0.4 mm Hg at 25°C (Stroud and Vernon, 1975).
                           <    WHI
                           v_/
[C02
H,
                             Cyclohexylammonium carbonate

     Ethanolamine carbonate is another carbonate found to be an effective VCI
(Uhlig, 1971) but is apparently not being used currently as a VCI in the United
States.

Benzoic Acid Salts--
     Benzoic acid salts of diisopropylamine, dicyclohexylamine, ethanolamine,
diethanolamine, triethanolamine, isopropylcyclohexylamine,  N-ethylmorpholine,
and naphthylamine have been tested and found to give "100% protective action
toward steel" (Putilova et al., 1960).  However,  these compounds are apparently
not used at the present time as VCIs in the United States.
                                       14

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     Rosenfeld et al. (1972) reported that arnine nitrobenzoates are much more
effective than amine benzoates or amine nitrites as VCIs.

Alternatives--
     Although Dichan was very recently the most widely used VCI, several VCI
producers are changing to compounds that do not contain nitrite salts.   The
substitute compounds were not identified by the companies;  however, patent
literature and trade publications indicate that substituted benzoate salts
(salts in which the anion contains a substituted benzoic acid group, e.g., a
chlorobenzoic acid anion) are the compounds most likely to  be used in place of
nitrites.  An example of a chlorobenzoate salt is:
                                            Cl
                Dicyclohexylammonium chlorobenzoate
VCIs for Nonferrous Metals

     Benzotriazole is one of the most effective compounds used as a corrosion
inhibitor for copper and other nonferrous metals such as chromium, nickel-
silver alloys, and zinc-nickel alloys (Sherwin-Williams, 1976).   It can be
prepared directly by the action of nitrous acid on o-phenylenediamine and by
the hydrolysis of an acylated or arylated benzotriazole.  It is  a white to
off-white crystalline powder which melts at 96 to 97°C (Damschroder and
Peterson, 1955).

     Much lower levels (about 0.01 to 0.1 as much) of VCI are needed to pro-
tect copper than to protect steel (Schneider, 1978).   For example, tissue paper
carrying 2% by weight benzotriazole interleaved between copper mill sheets pre-
vented tarnish for approximately 18 months.  A brown wrapping paper coated with
0.43 g benzotriazole/m2 and 10.8 g Dichan/m2 protected copper and steel against
water-saturated air containing 1% sulfur dioxide for 20 hr (Sherwin-Williams,
1976).

     Most of the uses of benzotriazole for corrosion inhibition are not as
VCIs.  The compound has been used in antifreeze and engine coolants, cleaners,
coatings, detergents, electrolytic processes, hydraulic and other functional
fluids, metalworking processes, polishes and waxes, and water-circulating sys-
tems (Sherwin-Williams, 1976; Schneider, 1978).  Table 3-1 shows the major
uses of benzotriazole compounds (Davis et al., 1977).
                                       15

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             TABLE 3-1.  MAJOR USES OF BENZOTRIAZOLE COMPOUNDS
ANTI-CORROSION  -  antifreeze compositions

                   hot water heaters and associated pipes of iron, copper,
                     and their alloys

                   electric generator water cooling systems

                   cleaning pastes and polishes

                   impregnated protective paper (for packing, wrapping, and
                     storage)

                   dry cleaning fluids

                   dishwasher detergent

                   metal lacquers

                   hydraulic and lubrication fluids

                   electrolytic deposition (improves hardness and brightness)

ULTRAVIOLET  STABILIZATION  -  plastics, especially polyolefins

                              other polymers, such as nylons and polyesters

                              clear coatings

                              paints and  pigments

                              oils

PHOTOGRAPHY  -  antifoggants

                emulsion tint agent

                UV absorber/stabilizer

                thermographic photocopying processes


Source:  Davis et al.  (1977)
                                      16

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     Competitors with benzotriazole (I) in some of these applications are
tolyltriazole (II), 2-mercaptobenzothiazole (III), phosphonates,  and chromates.
The structures of compounds I, II, and III are show below:
                                    II
                                                     III
     Benzotriazole is taking over many corrosion inhibitor markets where the
elimination of chromates is desired for environmental reasons (Schneider, 1978).
There are a few uses of benzotriazole as a corrosion inhibitor in consumer prod-
ucts reaching the general public (e.g., hydraulic (brake) fluids and antifreezes)
In addition, a product is marketed which consists of a sponge impregnated with
benzotriazole to be placed unwrapped in a cutlery drawer or chest to protect
silver (Schneider, 1978).

Alternatives--
     No alternatives for benzotriazole and tolyltriazole as VCIs were specif-
ically identified.

USES OF VCIs

     VCIs are used for corrosion control of both ferrous and nonferrous metals.
Over 90% of the amount presently being used is coated or impregnated in packag-
ing and wrapping materials.  VCIs are also currently being marketed as solid
crystalline products in the form of pellets, tablets, and powders, which are
often packaged in small permeable containers.
ing,
VCIs have many applications (Miksic, 1978;  Kravik,  1978) in the packag-
shipping, and storage of a wide variety of  items including:
     Artifacts in museums
     Ball bearings
     Computers
     Electrical transformers
     Gasoline engines
     Guns
     Hearing aids
     Marine electronic equipment
                                   Molds
                                   Motors
                                   Piping
                                   Process control devices
                                   Propane tanks
                                   Pumps
                                   Tanks
VCIs are used in cartridges, tablets, or powder form to protect the following
items:
                                       17

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     Computers

     Electrical equipment

     Junction circuits

     Process control equipment

     Switch boxes

     The major users of VCIs are discussed in the following paragraphs.

The Military

     The principal use by the military and military contractors is for ord-
nance, including storage of weapons, combat vehicles,  ammunition,  maintenance
tools, and equipment.  Small parts are wrapped in VCI  paper and sealed in con-
tainers.  VCI crystals are placed in the cavities of aircraft engines and tanks
in storage.  The present military specification calls  for an acceptable test to
determine the effectiveness of compounds used as VCIs, but not their safety.
Dichan and Dipan have been accepted by the military (Carroll, 1978).

The Automotive, Aircraft, and Tractor Industries

     These industries are the largest users of VCI paper.  The paper is used
to protect small parts, e.g., ball bearings, electrical components,  and gears,
which are shipped overseas or stored for a period of months.

Steel and Copper Manufacturers

     The steel industry uses VCI paper to wrap "black" plate, which  is untinned
steel, and tin plate produced for can companies.  Stacks of cut steel plate (3
x 6 ft) on wooden pallets are wrapped with VCI paper.   VCI paper containing
benzotriazole is used by manufacturers of copper and other nonferrous products
to prevent tarnish as well as corrosion.

Electrical and Electronic Equipment

     VCI crystals in small permeable bags or cartridges are used in  switch
boxes and cavities of large electronic machinery located in areas  having high
humidity, warm temperature, or a salt water atmosphere (Kravik, 1978).  Ben-
zotriazole-treated paper is used to wrap reels of copper wire and  electronic
equipment.  During subassembly storage, microwave components, electronic com-
puter parts, typewriters, and radio and television circuit boards  are protected
by benzotriazole-coated papers.   Manufacturers, such as Honeywell, Rockwell
International, General Electric, Westinghouse, and General Motors  also use VCI
paper for the protection of metal parts and components.
                                        18

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Uses by the General Public

     Currently the bu.lk of VCI paper and crystals is used by industry and not
the general public.  However, small amounts are used by individuals in the
storage of tools, guns, and sterling silver (Miksic, 1977; Kravik,  1978).

MARKET INFORMATION

     Based on information from numerous industrial sources, the total market
for VCI products is estimated to be between $7 million and $8 million per year.
Approximately 311,000 kg/year of various chemicals are used as VCIs (see Table
3-2).  Appendix D contains market information on VCIs and related products ob-
tained from nonconfidential information submitted to EPA by manufacturers and
importers as of January 1979.  Until very recently, the market was dominated
by Dichan,** but this product is rapidly being replaced by "nonnitrite" VCIs .*
By far the largest share of the market is represented by impregnated paper and
other wrapping materials; apparently the market for impregnated paper is much
greater than for other wrapping materials such as impregnated plastic films.

     The size of the overall market has been stable for the past 4 to 5 years
despite a reduction of VCI purchases by the military (Bell, 1978);  this reduc-
tion has been offset by the growth of the VCI paper market.

     The development of impreganted plastic wrapping material will probably be
a significant factor affecting the future growth of the VCI market, in partic-
ular, the development of "cold seal" films of polyesters which are impregnated
with VCI compounds is significant.  These products will provide a transparent
package which seals out moisture arid gives corrosion protection.  At the pres-
ent time, these products are produced only by the Orchard Paper Company and
sold as "Rapid Seal" (Van Winkle, 1978).

VCI-Impregnated Paper and Other Wrapping Materials

     The market for VCI-impregnated paper is estimated by industry sources to
be between $6 million and $7 million (Hutter, 1978).  No production figures
were available on the amount of each VCI compound used in this application.
     A discussion of the overall market for volatile amines as corrosion in-
       hibitors is presented in Appendix B.
     Boris Miksic, Chairman of the Volatile Corrosion Inhibitors Group
       (T-3A-4) of the National Association of Corrosion Engineers (NACE)
       in a letter to Norbert Page of NIOSH (January 1977) stated that he
       believed that the market for VCI compounds was "over 10 million pounds
       per year" (4,500,000 kg/year).  Our contacts with manufacturers and
       users of these products have indicated that the market is less than
       one-tenth that size.
     "Nonnitrite" VCIs are proprietary substitutes for Dichan (dicyclohexyl-
       ammonium nitrite) in which the nitrite anion has been replaced with
       another anion, for example, a substituted benzoate anion.
                                       19

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                TABLE  3-2.  U.S. MARKET  FOR VCI PRODUCTS,  1978
                                   Amount of VCI used  (thousands of kg)
                                 Impregnated paper
                               and other wrapping         All other VCI
 	Compounds	.	materials	  applications

  Dichan  (dicyclohexyl-                 95                       14
   ammonium nitrite

 Benzotr lazo I.e                          '!()                       0

 "Nonnitrite" VCIs         ,             170                      _2

      Total                             295                       16
 Source:  MRI estimates.
However, the total market can be estimated from the average loading factor,""
11 g/m2 (1 g/ft2) and the average cost of VCI paper, 24C/m2 (20C/yard2); thus,
over 27 mi.ll.ion m2 (30 million yard2) of VCI paper is produced per year ntil-
i/ing an esL.imat.ed 295,000 kg of VCI chemicals.  According to flutter (1978)
approximately one-third of this amount, or ahout 9!>,00() kg, is Dichan, and  11%,
or ahout 30,000 kg, is benzotriazole.  The remainder, about 170,000 kg, is es-
timated to be "rionnitrite" VCIs which have been used in place of Dichan (Hutter,
1978).

     Daubert Chemicals, the main producer and user of the nonnitrite VCIs, con-
siders the identity of the compounds and the amounts produced to be proprietary.
However, the information in the patent literature and trade publications indi-
cates that substituted benzoate salts of dicyclohexylamine and other fatty
amines are the likely replacements for nitrite salts.

     There are three major VCI paper companies:  Daubert Chemicals, which is
estimated to have 80% of the market; Ludlow Corporation, 15%; and Cromwell,
5%.  Mead, Scott, and International paper companies are firms which buy small
amounts of VCIs for more specialized products such as tissue for rolling sheet
and excelsior for drums holding copper fittings (Schneider, 1978).
     The loading factor is the amount of VCI ordinarily used in the manufac-
       ture of impregnated paper.
                                       20

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 VCI  "Crystals"

      Solid  VCIs  used  for  applications  other  than  impregnated paper are  referred
 to  as "VCI  crystals."   The VCI  crystal market  is  estimated  to he  slightly  less
 than $1  million,  which  is equivalent to  about  16,000  kg.  Dichan  represents
 about 85% of this market.  The  Olin Corporation is  the major producer of Dichan
 crystals, which  are marketed  (as  VP1®  260) by  the Shell  Chemical  Company to
 small customers.   The Alcon Company of New Orleans, Louisiana, also produces
 Dichan and  is a  major supplier  to the  military.

 Benzotriazole

      As  indicated previously, the amount of  benzotriazole used annually as a
 VCI  in paper was estimated to be  30,000  kg (Hutter, 1978).  This  amount is con-
 sistent with an  annual  VCI paper  production  of 27 million m2 and  a loading fac-
 tor  of 1 g/m2 (0.1 g/ft2).

      U.S. producers of  benzotriazole are Sherwin-Williams,  Eastman Kodak,
 Fairmount Chemical, Columbia Organic,  Mobil  Oil,  and  Sieflor (Appendix  D).

      Although Eastman Kodak sells benzotriazole through  its Organic Chemicals
 and  Photographic Chemicals Divisions,  quite  probably  most of the  benzotriazole
 is  produced for  captive use in  photographic  processes.   The Organic Chemicals
 Division sells benzotriazole as a laboratory chemical in small packages through
 dealers. Only two companies, whose names were not  revealed, have bought benzo-
 triazole in large amounts.  The Eastman  Kodak  representative did  not recognize
 these two firms  as users  of corrosion-inhibiting  chemicals  (Van Sice, 1978).

      Cross  (1978), Vice President of Marketing at Fairmount Chemical Company,
 had  no idea what the  total U.S. production of  benzotriazole is at the present
 time.  Fairmount produces benzotriazole  for  photographic use but  has been  un-
 able to penetrate the copper protection  market held by Sherwin-Williams (Cross,
.1978).  Since Sherwin-Williams  is the  major  producer  and has a big share of
 the  market, the  U.S.  International Trade Commission does not report benzotri-
 azole production figures.

      Schneider (1978),  Product  Manager for Triazole Products at the Sherwin-
 Williams Company, Chemical Division, estimated that world use of  benzotriazole
 as  a VCI was 68,000 kg  (150,000 Ib) in 1978.   Complicating  the estimate for
 U.S. consumption for  that purpose is the possibility  that a few companies  may
 import benzotriazole  to sell as a corrosion  inhibitor.   Although  several for-
 eign patents on  benzotriazole as  a corrosion inhibitor have been  issued to
 American Hoechst Corporation, the company stated  that none  of the benzotriazole
 produced by the  parent  firm is  imported  for  sale  in the  United States (Swift,
 1978).

 THEORIES OF THE  MODE  OF ACTION  OF VCIs

      Uhlig  (1971) stated  that the mechanism  of VCI  inhibition had "not  been
 studied in  detail" but  that protection is apprently due  to  adsorption of a
 film on the metal surface that  protects  against water and/or oxygen.


                                       21

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Nitrite ion may be supplied by the volatile nitrites to passivate* the metal
surface.

     According to Rosenfeld et al. (1972), the effectiveness of a compound em-
ployed as a VCI depends on its saturated vapor pressure, its capacity to be
adsorbed by the metal surface, and the presence of functional groups capable
of passivating the metal surface.

     Trabanelli and Zucchi (1976) and Trabanelli et al. (1967) have reviewed
some of the theories which have been postulated concerning the mechanism by
which VCIs protect against corrosion:

     *    The inhibitor saturates the atmosphere surrounding the metal surface,
          reducing the relative humidity at the metal-gas interface below a
          certain critical value.

     *    The adsorbed inhibitor renders the metallic surface hydrophobic,
          thereby preventing contact of the metal with moisture in the atmo-
          sphere.

     *    The inhibitor produces a strong electrical resistance on the metal
          surface which reduces the corrosion current.

     *    The inhibitor renders the metal surface alkaline causing the cor-
          rosion rate to become negligible.

     *    The inhibitor causes passivation of the metal surface by saturating
          the metal-gas interface with inhibitor and by polarizing the metal.

     Very little information is available concerning the mechanism by which VCIs
prevent corrosion.  However, the following observations are significant.  Black
and Wachter (1953) stated that since Dichan (dicyclohexylammonium nitrite) is
moderately water-soluble, its protection ability cannot be attributed to forma-
tion of a hydrophobic-adsorbed film.   The pH of aqueous solutions of Dichan is
near 7, so its action cannot be ascribed to the development of an alkaline pH.
Dichan does not react detectably with oxygen, so it cannot be an oxygen scav-
enger.  It is not especially hygroscopic, so its action cannot be that of a
desiccant.  Thus, the most reasonable mechanism for the VCI properties of
Dichan is that its volatility serves as a means of transport to the metal sur-
face where it contributes a nitrite ion (a recognized contact corrosion inhib-
itor) to condensed or adsorbed moisture on the metal surface (also in Wachter
et al. , 1951).
     Passivation is a process in which the corrosion of a metal surface is
       inhibited by the formation of an insoluble compound by precipitation
       or reaction.  Anions of weak acids, e.g.,  nitrite, chromate,  benzoate,
       silicate, phosphate, and borate, form passivating films that  stabilize
       the metal oxide coating (Uhlig, 1971).
                                       22

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     The mechanism of "nonnitrite" VCIs is probably similar, except that the
nitrite ion is replaced by a substituted benzoate ion.

     Benzotriazole is thought to form a 1:1 chemical complex with copper ions
on the copper surface.  This reaction results0in the formation of a highly im-
permeable physical barrier layer 50 to A,000 A thick (Sherwin-Wi 1 1. i;ims,  1076).

POTENTIAL NITROSAMINE FORMATION IN DICHAN AND RELATED COMPOUNDS

     The major VCI, Dichan, would be expected to be especially vulnerable to
nitrosamine formation because it is a nitrite salt of a secondary amine.  As
described in Appendix C, "Nitrosamine Formation Potential," secondary amines
are readily nitrosated by nitrous acid or nitrite under a wide variety of con-
ditions.  However, little published information was found concerning the con-
version of Dichan to the corresponding nitrosamine.

     An early experiment on the chemical and thermal stability of Dichan
(Wachter et al., 1951) showed the possibility for nitrosamine formation.  How-
ever, nitrosamines were not considered a serious hazard at that time, and the
extent of nitrosamine content during decomposition studies was not measured.

     Dichan was considered "remarkably stable"; a plot of years required for
total decomposition versus temperature is presented in Figure 3-1.
                       10    21
32    43    55   66
Temperature, °C
77
  Source:  Wachter et al. (1951)

                  Figure 3-1.  Thermal stability of Dichan.
                                       23

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For the study of the pure crystals, Dichan was sealed in glass tubes and
stored at different constant temperatures for extended time periods.  A
variety of Dichan coated and impregnated papers were stored separately in
waxed paper envelopes in a closed box at room temperature (about 72°F) for
periods of 1 to 3 years.

     The Dichan content of the crystals and the paper was measured on the basis
of the nitrite content.  The observed decreases in nitrite content could have
been the result of the conversion of Dichan to the nitrosamine or the nitrate
salt; however, no attempt to detect either of these products was reported.

     Recent information obtained from an industrial source indicates that com-
mercial Dichan contains "extremely low" amounts of nitrosamine.  These amounts
were not quantified but were said to be less than 1 ppm (Palm, 1978).

Nitrosatnines from Benzotriazole

     The preparation of benzotriazole and its derivatives is from the appro-
priately substituted o-phenylenediamine and nitrous acid.  The photographic
grade of benzotriazole is almost 100% pure, and the purity of the technical
grade is 99.7 to 99.8% (Schneider, 1978).

     Nitrosation might occur under the reaction conditions so that even when
used without nitrite some nitrosamine could be present.  However, Schneider
(1978) stated that Sherwin-Williams had not been able to form the nitrosamine
of benzotriazole under conditions such as varying the pressure, temperature,
and nitrogen oxide concentration.  However, the firm now recommends that so-
dium nitrite not be used with benzotriazole.

POTENTIAL FOR ADVERSE ENVIRONMENTAL EFFECTS

     Little is known concerning the stability of VCI products in the environ-
ment.  Dichan is known to be thermally unstable (Shell, 1972; Wachter et al.,
1951).  .It is also known to be extensively decomposed by sunlight (20 to 50%
decomposition in 60 days) (Wachter et al., 1951).   As a VCI, Dichan enters the
atmosphere where it is probably not a long-lived constituent because of its
susceptibility to photolysis.  However, no studies have been found concerning
the nature or toxicity of its decomposition products.

     Also, no reports have been found concerning the environmental effects or
stability in the environment of Dichan substitutes or benzotriazoles.

     As pointed out earlier, the biggest use of VCIs is in wrapping materials,
especially impregnated paper.  Archer and Wishnok (1976) detected N-nitroso-
N,N-dibutylamine in a sample of "commercially produced, corrosion-resistant
film of unknown composition."  The concentration was estimated to be about 100
ppm.  However, no indication was found that dibutylamine or any of its salts
are actually used in products of this kind.  Also, Wishnok stated that he did
not know the commercial source of the sample, nor had their group done any fur-
ther studies since the one which was published.  The dibutyl nitrosamine was
"tentatively" identified by a highly reliable analytical methodology, gas


                                       24

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chromatography-mass spectrometry.  Archer (1978) stated that the supplier of
the sample had responded that the identified compound was not one which could
be expected.

     Archer and Wishnok also prepared "a corrosion-resistant polyethylene film
with a surface layer of morpholinium nitrite in an acrylic binder covered with
a layer of latex."  This film was subsequently (time unspecified) found to con-
tain nitrosomorpholine.  The nitrosamine concentration of a methylene chloride
extract of the film was 90 ppm.  These investigators also found 3,000 ppm of
nitrosamine in an "unpurified" sample of the morpholinium nitrate which they
prepared by a procedure in which carbon dioxide was bubbled through a mixture
of morpholine and sodium nitrite in methanol.

     Benzotriazole in contact with air, water, or sunlight is likely to be
quite stable and persistent.  However, the perceived potential for environ-
mental contamination has been small, and the attention paid to it has been
negligible (Davis et al, 1977).
                                      25

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                                   SECTION 4

                       VOLATILE AMINES IN BOILER SYSTEMS
     VCIs  such  as Dichan are not used in steam boilers; the compounds are too
 expensive  and would probably be decomposed by the high temperatures  (Wachter
 et  al.,  1951; Baker,  1954).  However, a variety of volatile and nonvolatile
 amine  compounds are employed to control corrosion in boilers.  Also  examined
 is  the possibility that amines added to boilers might form nitrosamines
 through  reaction with nitrites, nitrates, oxides of nitrogen, or any other ni-
 trosating  agent.  The market for boiler water amines is also discussed.

     This  section of  the report considers the current range of chemical prac-
 tices  used to manage  boiler water  in heating, process steam generation, and
 electrical power production.

 BOILER WATER TREATMENT PRACTICES

     The water  used in boilers is  treated by:  (a) removing dissolved solids
 that would form adherent scale (softening or deionization); (b) removing dis-
 solved gases, including oxygen and carbon dioxide; (c) adding alkali to main-
 tain a desirable pH;  and (d) introducing chemical agents that act as oxygen
 scavengers, neutralize carbon dioxide in the condensate, serve as passivators
 or  corrosion inhibitors, and maintain precipitated sludge  in a suspended con-
 dition.  The sections which follow consider the water management practices
 that are typical for  boilers operating from low pressure to super-critical
 pressures, with special emphasis upon the use of amines and any potential ni-
 trosating  agents.

     The extent of pretreatment required for boiler feedwater and the type of
 compounds  used  to prevent  scale formation, embrittlement,  and corrosion are
 largely  dictated by the type of boiler employed and its operating pressure.
 One convenient, though arbitrary,  classification of boiler types is  shown be-
 low (Hamer et al., 1961):

                                                                 Maximum
        Boiler                 Pressures (Ib/in )           Temperatures (°G)

Low-pressure                      Up to 200                        190
Intermediate-pressure             200 to 500                       240
High-pressure                     500 to 2,000                     335
Very high-pressure                2,000 to 3,209                    375
Super-critical                    Above 3,209                       375
                                       27

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 Feedwater Requirements

      The  requirement  for  feedwater  purification  becomes more  stringent  as  the
 operating pressure  increases.   The  concentration of  dissolved solids  in high-
 pressure  and very high-pressure boilers  must be  held to much  lower  levels  than
 for low-pressure or intermediate-pressure  boilers.   Table  4-1 gives the gen-
 eral characteristics  typically required  for feedwaters.  Typical properties of
 the corresponding boiler  waters are shown  in Table 4-2.

      Very large numbers of low-pressure  boiler systems—these include rela-
 tively small heating  systems  and moderately sized industrial  boilers—are  op-
 erated with minimal pretreatment of the  feedwater.   Precipitation or  exchange
 softening may be used, or proprietary  boiler compounds may be added to  the
 feedwater to achieve  what is  termed "internal treatment" in which all chemical
 treatment of the water is carried out  entirely within the  boiler system it-
 self.

      Internal treatment is widely used for the smaller and simpler boilers,
 such as the various types of  shell  boilers, but  under certain conditions can
 also be used for watertube boilers.  This  type of treatment requires  the main-
 tenance of an adequate excess  of sodium  carbonate or phosphate in the boiler
 water to  precipitate  substantially  all of  the hardness in  a form which  will
 not adhere to boiler  surfaces.

      Most boilers designed to  operate  above 200  lb/in2 utilize preliminary
 treatment of water  to remove  hardness  and  scale-forming impurities.   For
 larger boilers,  the use of demineralization or evaporation to provide high
 purity feedwater is widespread.

 Oxygen Removal

      After pretreatment,  feedwater  is  treated to remove oxygen.  The  usual
 practice  is to subject feedwater to physical deaeration by bringing it  into
 contact with steam  in the feed heater.   An effective deaerator will reduce the
 dissolved oxygen to about 0.07 ppm  (70 ppb) or less.  Alternatively,  the water
 may be held in the  feedwater  tank at 90  to 95°C  for  a period  of 30 min  to  re-
 duce dissolved oxygen to  about 2 ppm.  This type of  oxygen removal  is prac-
 ticed on  smaller, less elaborate boiler  systems  operating  at  250 lb/in2 or
 less.

      Oxygen is further removed by the  use  of chemical reducing agents.  The
.most important oxygen scavengers are sodium sulfite  and hydrazine (Francis,
 1962).  Although other compounds have  been reported  in the literature,  the
 boiler experts and  operators  interviewed in this study did not report using
 any other agents.

 Sulfite—
      Sodium sulfite reacts with oxygen to  form sodium sulfate:
                                      28

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                                      TABLE 4-1.   RECOMMENDED  CHARACTERISTICS  OF  BOILER  FEEDWATER
          Type of boiler
                                                 Recommended  characteristics
     Hardness
(expressed  as calcium
     carbonate)
        (ppm)
Alkalinity
Oxygen content
                                         Remarks
       Low-pressure
          (up to 200 lb/in2)
       Medium-pressure
         (200-500 lb/in )
vo
                                      < 20
        < 10
                        Sufficient to give
                          pH value of 9.0
                          or greater
                        Sufficient to  give
                          pH value of  9.0
                 May occasionally be
                   necessary to reduce
                   to below 0.14 ppm
                                                                            0.007-0.03 ppm
                     Corrosion of feed systems  is  usually prevented
                       by maintaining correct alkalinity in feed-
                      - water; corrosion of boiler  is  prevented by
                       alkalinity control and by various mechani-
                       cal arrangements for discharging gas into
                       the steam space.  Where  oxygen content must
                       be reduced, physical deaeration is used.
                                          Good physical deaeration may be  sufficient to
                                           give desired oxygen content;  if  not,  sodium
                                           sulfite or hydrazine are added.
       High-pressure
         (500-2,000 lb/in  )
        < 1
                        As for medium-
                          pressure  boilers
                          Nil
                                          Good physical deaeration followed by contin-
                                           uous addition of sodium sulfite or hydra-
                                           zine is essential.
       Source:  Hamer,  Jackson, and Ttmrston, 1961.

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                                                         TABLE  4-2.     RECOMMENDED  CHARACTERISTICS  OF  BOILER  WATER-
                                                                                                                                                                    a/
                     Hardness
                  (expressed as      Sodium phosphate
                calcium carbonate)  reserve (expressed
Type of boiler         (ppm)           as P04)  (ppm)
                                                                                               commended characterist
                                                             Alkalinity
                                                                                                                                                          Silica
                                                                              Alternative treatment chemicals _tg prevent caustic cracking     Sodium sulfite   content   Dissolved
                                                                                Sodium sulfate       Sodium nitrate-                          excess  (ppm)     (ppm)      solids
                                                                                  content     .        content        Phosphate content        as such       as such      (pp«n)
                                                                                                                                                                                         Remarks
Low-pressure     -^5 when carbonate
 (up to 200 Ib     is used.
 lb/in2)
                  2 when phospha
                                        30-90C           Carbonate alkalinity   Sufficient to give
                                     (where used)          should be S 200        Na2S04/NaOH
                                                          ppm expressed as       weight ratio
                                                          calcium carbonate      $ 2"5 and pref-
                                                          and probably
                                                          > 300 ppm.
                                                                                erably > 3-0 in
                                                                                boiler water.
                    Sufficient to give    Sufficient to gi'
                      ratio of NaN03       coordinated
                      to  total alka-
                      linity (includ-
                      ing phosphate if
                      present) ex-
                      pressed as NaOH
                      S 0-4 in boiler
                      phosphate treat-
                      ment, but rarely
                      used  in low-
                      pressure boilers.
                                           50-200
                                        '.where used)
                                                                                                                                                            Any
                                                                                      3,000-
                                                                                      20,000
                                                                             Dissolved solids depend
                                                                               type of boiler,d
Medium-
  pressure
  (200-500 Ib
  lb/in2)
                                        30-90C
                                                        Sufficient  to give
                                                          pH value  of 11
                                                          or more;6 alkali
                                                          content  S 10% of
                                                          dissolved solids.
As for  low-
  pressure
  boilers.
As for  low-
  pressure
  boilers.
                                        Sufficient for co-
                                          ordinated phos-
                                                                   10,000-    Dissolved solids 'figures apply
                                                                    3,000       to watertube boilers and

                                                                               creases.   Suspended solids
High-pressure
  (500-2,000
                                                        As for medium*
                                                          pressure  boilers.
As for low-
  pressure
  boilers.
As for low-
  pressure
  boilers.
As for medium-
  pressure
  boilers.
                                                                                      3,000-
                                                                                      1,000


                                                                                                                                                                                 safety  from turbine blade
                                                                                                                                                                                 deposits, but higher fig-
                                                                                                                                                                                 ures are often acceptable.
d  Figur.
                 follows:

                 Lancashire boiler
                 Economic boiler
                 Locomotive  boiler
                                               20,000 ppm
                                               15,000 ppm
                                                4,000 ppm
                                                3,000 ppm
e  Measured at atmospheric temperature,

f  Sodium sulfite excess depends primarily on efficiency of initial  mechanical deaeratlon  (including that due-to retention in hot
   feed  tank).  If mechanical deaeration is efficient and reliable,  relatively low sodium  sulfite excess only is required.
                                                                                                 res apply
                                                                                                 s, and
                                                                                                 e in-
                                                                                                                                                                                 also be  take
                                                                                                                                                                                               nto account.
                                                                                                                                                                                 Fig
                                                                                                                                                                                 appear  to giv*1 complete
                                                                                                                                                                                 saftty  from turbine blade
                                                                                                                                                                                 deposits, but higher fig-
a  For reccxonended characteristics where internal treatment is used,  see  text.

b  Measured by EDTA method.

c  Typical values; reserve depends on possible rate of depletion and  frequency of replenishment.  Large  quantities may be required where coordinated phosphate treatment
   is used.
Source:   Hamer, Jackson,  and Thurston, 1961.

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                      2 Na SO  + 0  - -2'Na SO


Sulfite is generally used as an oxygen scavenger for removal of oxygen from
water that has been physically deaerated.   Preliminary scrubbing to remove
oxygen is essential, both to reduce the cost of chemicals and to prevent an
undue buildup of dissolved solids content  of the boiler water.

     There are certain objections to the use of sodium sulfite  as a deoxygen-
ator, apart from the fact that it cannot be used without increasing the dis-
solved solids content of the boiler water.   A more important objection is its
liability to decompose at the higher boiler pressures to form hydrogen sulfide
or sulfur dioxide.  The fact that sodium sulfite does decompose in operating
boilers seems to be established.  As a general rule, sodium sulfite can be
safely used as an oxygen scavenger in boilers working at pressures up to at
least 1,000 lb/in2, provided that the boiler water is alkaline  and the con-
centration of sulfite is not above about 10 ppm (Na2S03).

Hydrazine--
     Hydrazine is a powerful reducing agent which reacts with dissolved oxygen
under boiler conditions as follows:


                   N2H4 + °2 -- * 2 H2° + N2

It is thus capable of removing oxygen from the boiler water without increasing
the dissolved or suspended solids content  (Fletcher, 1958; Woodward, 1958).
Hydrazine also decomposes under boiler conditions:
The formation of ammonia from the hydrazine is regarded as advantageous in
reducing the risk of corrosion by dissolved carbon dioxide in condensate.

     As shown in the equation, one molecule of hydrazine is needed to remove
one molecule of oxygen.  In practice, however, a 100% excess of hydrazine in
the feedwater is generally used so as to ensure rapid removal of the oxygen.

Prevention of Caustic Embrittlement--
     Sodium nitrate was formerly added to boiler water to prevent caustic em-
brittlement.*  Boiler experts were almost unanimous in pointing out that the
occurrence of caustic embrittlement problems today is so rare that the embrit-
tlement problem and chemical treatment to avoid it have all but disappeared
(Thiedke, 1978; Johnson, 1978; Walters, 1978).  Walters (1978) stated that
nitrates have not been included in boiler compounds since about 1960.  Thiedke
     Caustic embrittlement is the term used to describe the weakening of
       ferrous alloys which occurs when the alloys are under stress and
       exposed to caustic.
                                      31

-------
suspected that compounds offered by some of the smaller firms might still con-
tain nitrates as a precautionary measure (Thiedke, 1978).

     Coordinated phosphate treatment—Conditioning of carefully purified feed-
water to maintain the desired pH at "zero-caustic" conditions is the most com-
mon means of avoiding caustic embrittlement.   The technique is employed for
boilers in the 500 to 1,800 lb/in2 range (Fryling, 1966;  Purcell and Whirl,
1942).  This treatment involves adding sufficient acid sodium phosphate to the
boiler water.

Chemical Treatment of Condensate Systems —
     Condensate systems can be chemically treated to control corrosion damage
caused by water and carbon dioxide.  The treatment chemicals consist of neu-
tralizing amines, filming amines, hydrazine,  and, in many cases, ammonia.

     Neutralizing amines—When condensate is  to be used as feed for boilers,
it is often necessary to reduce the pickup of iron so that the iron content is
less than 0.01 to 0.1 ppm, depending on pressure.  The pH level of the con-
densate should then be kept at about 9 by injecting a soluble neutralizing
amine into the boiler feed or the steam line.  The amine volatilizes with the
steam and combines in the condensate with the carbon dioxide to form bicarbo-
nates or carbonates.  On returning to the boiler, the amine carbonates decom-
pose to reform the amine and carbon dioxide.   The process is to some extent
then repeated.  Losses occur through blowdown and leakage.

     The compounds used for this purpose include ammonia,  cyclohexylamine,
morpholine, 2-diethylaminoethanol, methylpropylamine, and others (Hamer et al.,
1961).  The physical properties of these amines are presented in Appendix A.
The use of ammonia has sometimes been considered objectionable since, espe-
cially in the presence of small amounts of oxygen, it can cause the corrosion
of equipment made of copper or copper alloys.  Ammonia is widely used, how-
ever, and corrosion of copper is prevented by maintaining the dissolved oxygen
content of the feedwater at very low levels.   Cyclohexylamine and morpholine,
on the other hand, do not cause such corrosion, at least at the concentrations
employed for preventing corrosion of ferrous  metals.

     The choice between ammonia and one or another of the organic amines de-
pends on the quantities required and, hence,  on the cost.   The requirements
depend on their relative basic strengths and  volatilities.  Under working con-
ditions, very much smaller amounts of ammonia than of the organic amines are
needed to raise the pH value of pure water by a given amount; furthermore, the
price of a unit weight of ammonia is very much lower than that of either of
the liquid amines.  These advantages of ammonia are to some extent offset,
however, by the fact that the volatility of ammonia in steam is so high that
in some plants a large proportion will remain in the vapor phase and the de-
sired effects of raising the pH value at the  point where condensation first
takes place will not occur unless large amounts of ammonia are used.  Ammonia
appears to provide the cheapest and most effective method of protecting con-
densate systems from corrosion, provided that the oxygen content is low so
that attack on copper equipment can be disregarded.
                                      32

-------
     The choice between cyclohexyLamine and morphol ine is difficult Lo re-
solve.  Both amines appear to be equally stable substances;  each amine decom-
poses under boiler conditions at temperatures above 370°C (Archibald et al.,
1953).  On the other hand, more recent work (Feitsma, 1958)  suggests a de-
composition temperature at 266°C for morpholine and 288°C for cyclohexylamine.
Both have been used successfully (Rivers and Sonnett, 1950;  Corey, 1947) in
boilers operating at pressures up to about 1,500 lb/in2.  Their boiling points
are close together—cyclohexylamine boils at 134°C and morpholine at 129°C--
and their volatilities might accordingly be expected to be similar.  Cyclo-
hexylamine forms a constant boiling mixture (azeotrope) with water at 97°C,
and this provides it a volatility in steam about 10 times greater than that of
morpholine, which forms no azeotrope.  Thus, morpholine condenses out more
completely than cyclohexylamine at the point where condensation first takes
place.  However, cyclohexylamine is the stronger base of the two and is much
more capable than morpholine of raising the pH level of condensate when it is
present in equal quantities.  The high volatility of cyclohexylamine also im-
plies that the available reserve in the boiler water will be smaller than with
morpholine for any given amine dose in the steam.  Table 4-3 presents typical
concentrations.
          TABLE 4-3.  QUANTITIES OF AMINES REQUIRED TO OBTAIN PARTICULAR
                            pH VALUES IN PURE WATER
       Amine
Conditions
                                                   Amount  needed
 Ammonia
 Cyclohexylamine
 Morpholine
C02 absent
C0~ absent
C02 present
C0£ absent
C02 present
0:2 ppm to give pH 9                    .

1 ppm to give pH 9
2-3 parts per part of C02 to give pH 8-1
  (corresponds to bicarbonate)
2-0 parts per part of C02 to give pH 7-4
1-4 parts per part of C02 to give pH 7
4 ppm to give pH 9
2-0 parts per part of
                                       (corresponds  to bicarbonate)
                                                          C02  to  give pH  7-4
 Source:   Hamer  et  al.  (1961).
     It appears from current operating experience that the maintenance of pH 9
in the condensate is adequate to ensure that steam/water systems will be pro-
tected against corrosion.
                                      33

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     In estimating the overall requirements where part of the amine is re-
cycled, allowance must be made for losses in unrecovered steam and also to
some extent in blowdown.  Sufficient amine must, therefore, be used not only
to deal with fresh carbon dioxide entering the system, but also to make good
those losses.

     Filming amines—Certain straight-chain amines (containing 10 to 20 carbon
atoms) have been found useful for controlling corrosion in steam-condensing
systems in which the amines can form a protective adsorbed layer.  This layer
acts as a barrier between the metal and any liquid water, thus protecting the
metal from attack by water containing dissolved oxygen or carbon dioxide.
Octadecylamine (synthetic stearylamine, C18H37NH2) is the material most com-
monly employed.  Typically, the amine effects a reduction in corrosion of 80
to 95% with steam containing 4 to 60 ppm of carbon dioxide in the presence of
oxygen at boiler pressures in the range 100 to 600 lb/in2.  It must be sup-
plied continuously to the steam, for the film does not appear to be very per-
sistent in operating conditions.  The amine is either injected into the steam
lines or is pumped directly into the boiler where the amine distills off with
the steam.  Feeding the amine directly to the boiler is reported to be inad-
visable because of the risk of thermal decomposition.  The amine is stable,
however, to at least 425°C, and some authors have claimed stability at much
higher temperatures, e.g., 535°C and above (Fryling, 1966).

PRESENT STATUS OF USAGE OF AMINES IN BOILERS

     From discussion with boiler experts, it became clear that the chemical
treatments currently employed with various types of boilers may differ from
the standard methods reported in the literature (Webb, 1978; Thiedke, 1978).
Therefore, the views and opinions of the sources consulted have been set forth
as reflecting the more current commercial practices.

     Major neutralizing amines currently used to treat boiler feedwaters are
cyclohexylamine, morpholine, 2-diethylaminoethanol, and methylpropylamine
(Hollingshad, 1978), and ammonia.  Benzylamines are frequently mentioned in
the literature as neutralizing amines for boilers, but Labine (1978) was not
aware of any such commercial use of benzylamines.

     Filming amines used to treat boiler waters or steam condensate lines di-
rectly include octadecylamine and other fatty amines containing at least 12
carbon atoms.  These may also include secondary amines.  For example, Armak
Chemicals of Chicago produces the Ethomeen® series of secondary C12 to C18
amines that are sometimes used for boilers (Labine, 1978).  The filming amines
tend to foul pumps and strainers and other parts of a boiler system, and their
popularity is declining (Hollingshad, 1978).   However, if the neutralizing
secondary amines had to be replaced with other substances, Labine (1978) indi-
cated that filming amines would be used.  Other experts believed that hydra-
zine and ammonia would be the more likely replacements for neutralizing
amines.
                                      34

-------
     The producers of boiler water additives usually formulate products with a
mixture of amines having different volatilities.   If the system covers rela-
tively short distances, e.g., in a power plant where the boiler, turbine,  and
condenser are in close proximity, the amines used do not need to be highly
volatile.  In a refinery, where miles of piping may be employed, a product
volatile enough to carry to the end of the system is needed.   By applying the
proper blend of high- and low-volatility amines,  a product uniquely suited to
the particular boiler system's geometry can be provided (Hollingshad,  1978).

     Several contacts, including Hertz (1978) of Nalco Chemical Company,
stated that nitrites are not normally added purposely to boilers.  They are,
however, used in closed heating or cooling systems, possibly with amines'"
(Labine, 1978; Hollingshad, 1978; Gabrelli, 1978).  Nitrites might come in
contact with boiler water because of some failure of a nitrite-containing
closed system incorporated within a boiler system (Hollingshad, 1978).  Webb
(1978) stated that in modern-day power plant practice, the only possible use
of nitrites would be as "boron nitrite" in the closed cycle cooling water (in
place of sodium dichromate).  Other industrial sources specified the use of
sodium nitrite plus a borate buffer; and it is likely that such a combination
is what Webb referred to as "boron nitrite."

     Nitrates are also not intentionally added to boiler waters.  They may
rarely be present because a water softener might have been recharged with ni-
tric acid (not a common practice) or because the plant is a meat plant
(Labine, 1978).  Nitrates have been used in the past as part of the "boilout"
compound to clean down boilers as a precaution against caustic embrittlement
(Murphy, 1978), but this method is now considered obsolete.

MARKET INFORMATION

     About six volatile amines are in general use as boiler water additives
(Hollingshad, 1978).  These are listed below in Table 4-4 along with an esti-
mate of their current annual consumption in boiler water.  Appendix D contains
available market information on these amines and related products obtained
from nonconfidential information submitted to EPA by manufacturers and import-
ers as of January 1979.  A discussion of the overall market for amines as cor-
rosion inhibitors is presented in Appendix B.

     Calgon, Nalco Chemical Company, and Betz Laboratories are the largest
suppliers of boiler water additives.  Olin Water Services, Mogul Corporation,
Dearborn Chemical Division, Chemed Corporation, and Drew Chemical Corporation
are intermediate-sized companies; and there are a great many small companies.
The eight named companies, however, probably represent 90 to 99% of the market
for these materials (Hollingshad, 1978).
     Boilers are considered open systems because of loss of steam or conden-
       sate and the drainage of "blowdown," the periodic removal of concen-
       trated solids in the boiler.
                                      35

-------
             TABLE 4-4.  ESTIMATED CONSUMPTION OF SELECTED
                           AMINES AS BOILER WATER ADDITIVES


                                               Estimated
                                            1978 consumption
               Type of amine                 (metric tons)

            Neutralizing amines

              Cyclohexylamine                 3,200-3,600
              Morpholine                      1,800-2,200
              2-Diethylaminoethanol             900-1,400
              Methylpropylamine                       400
              All others    "                  	200

                   Total                      6,500-7,800

            Filming amines

              Octadecylamine                         2,300
              All others                               200

                   Total                             2,500



            Sources:  Stevens (1978) and  MR! estimates.
     About 40% of the total annual U.S. cyclohexylamine production is used for
pH adjustment in boiler systems.  It is sold directly to water treatment firms
(Meek, 1978).

     The total demand for morpholine in 1975 was about 11,000 metric tons.
About 2,700 metric tons were used in corrosion inhibitors (of this quantity,
1,800 to 2,200 metric tons were used as neutralizing amines in boiler water -
see Table 4-4); about 3,600 metric tons went into rubber chemicals; and about
900 metric tons went into each of the following categories:  optical brighten-
ers, waxes and polishes, alkylmorpholines,  miscellaneous, and exports (Mjos,
1978).  Several volatile boiler water amines are permitted by the U.S.  Food
and Drug Administration (FDA) to be "safely used in the preparation of steam
that will contact food" (Federal Register,  1977).  According to the FDA, steam
in direct contact with food may contain less than or equal to 10 ppm cyclo-
hexylamine, less than or equal to 15 ppm 2-diethylaminoethanol, less than or
equal to 10 ppm morpholine, or less than or equal to 3 ppm octadecylamine (all
                                      36

-------
of these with the proviso that the steam is not to contact milk and milk prod-
ucts) (Code of Federal Regulations, Part 121.1088, 1976).

     Less than 4,000 metric tons of 2-diethylaminoethanol  was produced in the
United States in 1976 (Mullins, 1978).   2-Diethylaminoethanol is also used in
the preparation of medicinals and antimalarials.

     Methylpropylamine has only recently been used as a boiler water neutral-
izing amine (Stevens, 1978).

POTENTIAL. FOR NITROSAMINE FORMATION IN BOILERS

     There is no experimental evidence to indicate whether or not nitrosamines
are formed in boilers as a result of the addition of boiler-water amines.
Most boilers are operated under conditions which would (a) limit the possibil-
ity for nitrosamine formation and (b) probably result in the destruction of
any nitrosamine that might be formed.  However, under certain circumstances,
the possibility for nitrosamine formation is conceivable.   These possibilities
are discussed below.

Modern High-Pressure Boilers

     Nitrates and nitrites are potential nitrosating agents for boiler water
amines.  However, neither nitrates nor nitrites are ordinarily added to boiler
water (Hollingshad, 1978).  For some high-pressure boilers, such as those used
by electric utilities, high purity water is essential.  As pointed out ear-
lier, purification procedures include the careful removal  of dissolved solids,
including nitrates which occur in most untreated waters in the range 1 to 10
ppm.  Some purification procedures require deionization of the water, and this
process would remove nitrate and nitrite (as well as other inorganic ions).
However, nitrosamines could possibly be introduced into water by resins used
for deionization; samples of deionized water have been found to contain as
high as 250 ng/liter of N-nitrosodimethylamine (Cohen and  Bachman, 1978).

     Other potential nitrosating agents are oxides of nitrogen from air.  How-
ever, the presence of dissolved oxygen and carbon dioxide  in boiler water is
undesirable; therefore, nearly complete deaeration of boiler water is ordinar-
ily employed.  These procedures would be expected to reduce greatly the con-
centration of dissolved nitrogen oxides in the water.

     A further detriment to the formation and stability of nitrosamines in
boilers is the fact that they are operated at high pH values, around pH 9 or
10.  The classical secondary amine-nitrite reaction would  not be expected to
occur at these pH values although the nitrosation of amines by oxides of ni-
trogen occurs rapidly at these pH values (see Appendix C).

     Although there are limited data on the thermal degradation of nitrosa-
mines in water, most of them are known to be thermally unstable, especially at
temperatures in the range of 300°C.  Temperatures of 250 to 300°C are attained
in high-pressure boilers and sustained for relatively long periods of time.
                                     37

-------
Thus, eventual thermal decomposition of most nitrosamines would be expected
under these conditions.  Furthermore, there is evidence that the thermal sta-
bility of some amines is greatly reduced at high pH values such as found in
boiler water (Lakings, 1980).

Medium-Pressure Boilers

     Boilers operating in the pressure range of 100 to 500 psi (maximum tem-
perature about 240°C) utilize much different water treatment practices than
higher pressure boilers.  This type of boiler commonly utilized a coordinated
phosphate treatment system to allow operation with zero-added caustic or to
maintain the desired pH with very minor caustic additions.  Sodium sulfite (or
in some cases hydrazine) may be used as an oxygen scavenger.  Since the intro-
duction of welded boiler construction (about 1930) and stress relief of the
boiler parts before use, caustic embrittlement has become virtually a problem
of the past.  The practice of using sodium nitrate (at 200 to 400 ppm) to pre-
vent caustic embrittlement is unknown to all the boiler specialists who were
consulted in this study.

     Hence, the occurrence of nitrosamines in moderate-pressure boilers is not
likely to be attributable to reactions between organic amines and other chemi-
cals intentionally added to manage these boiler water systems.

Low-Pressure Boilers

     There are hundreds of thousands of relatively small, low-pressure boilers
(25 to 200 psi, maximum temperature less than 190°C) in use for heating and
process steam generation.  The majority of these boilers are treated inter-
nally by the use of proprietary boiler water additives, which typically con-
tain phosphates, sodium sulfite, and a sludge-conditioning polymer.  The oc-
currence of caustic embrittlement is so rare that none of the boiler compound
suppliers were aware of any additives which presently contain nitrates or ni-
trites.  However, they cautioned that some boiler additives formulated by some
of the numerous, small boiler treatment supply firms could still incorporate
nitrates and/or nitrites.  The water used as feed presents another possible
source of nitrite.  Hence, the possibility of reaction between neutralizing
amines and nitrates or nitrites is at least possible in some low-pressure
boiler systems.

Hot-Water Boilers

     So-called "hot-water boilers," used to circulate water to about 77°C for
heating or to generate low-pressure steam at 10 to 12 psi with 100% condensate
return, may employ sodium nitrite as a corrosion inhibitor.  These systems are
closed and require no makeup water since losses occur only if leaks are pres-
ent.  Chromate corrosion inhibitors are commonly used, but a combination of
sodium nitrite and borate buffer is also widely employed.  The water circulat-
ing systems do not use neutralizing or film-forming amines since the proper pH
is maintained by the buffer system.  The development of nitrosamines in hot-
water heating systems is regarded as extremely unlikely.
                                      38

-------
Reports of Nitrosamines in Steam Emissions from Boilers

     A recent survey of N-nitroso compounds observed that small amounts (0.002
Hg/g) °f N-nitrosomorpholine were found in the steam condensate from boilers
at a B. F. Goodrich plant which produces chemicals for the rubber industry
(Fan, Fajen, and Rounbehler, 1978).  The authors were unable to ascertain ex-
actly how this nitrosamine (or other nitrosamines detected at the plant) was
formed.  In the report, they speculated that it was most likely formed by the
transnitrosation reaction of morpholine with N-nitrosodiphenylamine.   The lat-
ter compound, a vulcanization retarder, is produced at this plant and was de-
tected at various locations within the plant in amounts ranging from 47 to
50,000 (Jg/g in bulk samples and from 0.3 to 47 |Jg/m3 in air samples.

     Morpholine is used at this plant as a starting material for the manufac-
ture of bismorpholine carbamylsulfenamide, an accelerator.  The N-nitrosomor-
pholine was detected at various locations throughout the plant, ranging from
0.002 (Jg/g in steam condensate to 731 (Jg/g in scrappings from staircases, and
from 0.07 to 6.8 |Jg/m3 of the compound in air samples.  The authors also ob-
served that this compound exists as a contaminant in morpholine (0.8 (Jg/g) and
this fact may account for its presence in the samples taken.

     Fajen (1979) of NIOSH provided additional information concerning these
studies.  Morpholine was also used as a neutralizing amine for the boilers at
the B. F. Goodrich plant.  Many of the steam lines at the plant were leaking,
and these leaks were the source of their samples.  The program team was con-
cerned that the steam emissions might contain N-nitrosomorpholine as a result
of the known contamination of the morpholine starting material.  However, this
was subsequently shown to be unlikely because it was not detected in the steam
emissions from boilers at other plants which used morpholine as a neutralizing
amine.

     As part of this program, 28 different plants were visited for the purpose
of detecting N-nitrosamine contamination.  Steam condensate samples were ex-
amined only when nitrosamines were detected elsewhere in the plants.   No sam-
ples of boiler blowdown were taken at any of the plants, and no record was
made of the operating characteristics of the boilers.  The foremen of the
boiler rooms were contacted in order to determine whether morpholine was used
as a boiler additive.  Bulk samples of the boiler additives were also taken
for analysis for the presence of morpholine and N-nitrosomorpholine.   Some of
the plants used morpholine; for example, five plants serving the rubber indus-
try used morpholine in the boilers.  However, of all the plants visited, only
the B. F. Goodrich plant was found to contain this nitroso compound in the
steam condensate from boilers.

     At the present time, it is not possible to rule out morpholine in the
boiler as a source of N-nitrosomorpholine contamination.  However, nitrosamine
formation via a transnitrosation reaction outside of the boiler appears to be
the most likely mechanism.  Transnitrosation can only occur when other nitro-
samine contaminants are present.
                                      39

-------
     Additional studies are required to clarify this situation; additional
steam condensates from boilers using morpholine (and other amines) should be
examined using sampling techniques which would preclude transnitrosation.
Also, similar examinations should be made of boiler blowdown.
                                      40

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                                 REFERENCES
Anonymous. 1964. Corrosion Inhibitors Anti-Corrosion Manual. Corrosion Preven-
  tion and Control. Scientific Surveys Ltd., London, p.  289-292.

Archer, M. 1978. Department of Nutrition and Food Science, Massachusetts
  Institute of Technology, Cambridge, Massachusetts. Personal communication
  to A. Meiners, August 28.

Archer, M. C., and J. S. Wishnok. 1976. Nitrosamine Formation in Corrosion
  Inhibiting Compositions Containing Nitrite Salts of Secondary Amines.
  Journal of Environmental Science and Health A-ll (10 and 11):583-590.

Archibald, F. L., J. W. Purssell, and F. G. Straub. 1953. Prevention of Metal
  Losses in the Wet Steam Areas of Steam Turbines. Proc. Amer. Power Conf.
  15:579.

Baker, H. 1954. Volatile Rust Inhibitors. Industrial Engineering Chemistry
  46(12 ):2592-2598.

Bell, Ms. 1978. Assistant Manager for VPI Paper Sales, Ludlow Corporation.
  Holyoke, Massachusetts. Personal communication to H. Owens, August 9.

Black, A. R., and A. Wachter. 1953. Defeating Corrosion. Vapor Phase Inhibi-
  tors Provide Easy Means of Protecting Steel from Rust. Ordinance. May-June.

Brophy, J. E., V. A. Fitzsimmons, J. G. O'Rear, T. R. Price, and W. A. Zisman.
  1951. Aqueous Nonflammable Hydraulic Fluids. Industrial Engineering Chemistry
  43(4):884-896.

Cohen, J. B., and J. D. Bachman. 1978. Measurement of Environmental Nitrosa-
  mines.  In:  Environmental Aspects  of N-Nitroso  Compounds  by  E.  A. Walker,
  M. Castegnaro, L. Griciute, and R. E. Lyle. IARC Publication No.  19. Inter-
  national Agency for Research on Cancer, Lyon, France, p. 369.

Corey, R. C. 1947.  Internal Corrosion of Furnace Tubes of High-Pressure Boilers.
  Combustion 18(9):39.

Cross, J  1978.  Marketing Vice-President, Fairmont Chemical Company, Inc.
  Newark, New Jersey. Personal Communication to B. Carson, August 1.
                                      41

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Damschroder, R. E., and W. D. Peterson. 1955.  1,2,3-Benzotriazole.  Organic
  Synthesis. Collective Volume 3. John Wiley and Sons,  Inc., London,  pp.  106-
  108.

Davis, L. N.,  J.  Santodonato, P.  H.  Howard,  and  J.  Saxena.  1977. Investiga-
  tion of Selected Potential Environmental  Contaminants:   lienzoLria^olet;.
  Final Report to Office  of  Toxic  Substances,  Environmental Protection
  Agency. EPA  560/2-77-001.:

Fan, S., J. Fajen, and D. Rounbehler.  1978.  Survey  for N-nitroso Compounds.
  Final Report by Thermo  Electron  Research  Center,  Waltham, Massachusetts,
  and National Institute  of  Occupational  Safety  and Health, Cincinnati,
  Ohio. July 14.

Fajen, J. 1979. Industrial hygienist,  National Institute  of Occupational
  Safety and Health, Cincinnati, Ohio. Personal  communication  to A. F.
  Meiners, July 17.

Federal Register. 1977. 42:14531.

Fietsma, R. 1958. Water Treatment  in Some Dutch  Power Stations.  Bull.
  Centre Beige Etude et Doc. Eaux. 11(40):105.

Fine, D. H. 1978. Thermo  Electron  Corporation. Waltham, Massachusetts. Per-
  sonal communication to  A.  Meiners,  August  15.

Fletcher, W. H. B. 1958.  Hydrazine and Ammonia as Complementary Reagents
  in Water Treatment. In:  Proc. Internat.  Conf., Bournemouth, England,
  May 1957. Whiffen and Sons, London,  pp. 115-117.

Francis, W. 1962. Boiler  House and Power  Station Chemistry. Arnold, Ltd.,
  London.

Fryling, G. R. Editor. 1966. Combustion Engineering.  Revised Edition. Com-
  bustion Engineering, Inc., New York, NY.

Gabrelli, Mr.  1978. Chief, Utility Boiler Water  Chemistry,  Combustion
  Engineering. Windsor, Connecticut.  Personal  communication to H. Gadberry,
  August 11.

Hamer, P., J.  Jackson, and E. F. Thurston.  1961.  Industrial Water Treat-
  ment Practice.  Butterworths.

Harman, D., R. E. Thorpe, and S. K.  Talley.  1951.  Soluble Metalworking Lu-
  bricant. U.S. Patent No. 2,562,844.  July  31.

Hollingshad, W. 1978. Technical  Support Group  Leader, Department of Specialty
  Products Development, Calgon Corporation.  Pittsburgh, Pennsylvania. Per-
  sonal communication to  A.  Meiners,  August  15.

                                    42

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Mutter, C. A. 1978. Vice-President, Daubert  Chemical  Company.  Hinsdale,
  Illinois. Personal communication to H. Owens, August  28.

Johnson, R. F. 1978. Cleaver Brools, Inc. Kansas  City,  Missouri.  Personal
  communication to Howard Gadberry.

Kravik, R. C. 1978. Hoffman Engineering Company,  Division of  Federal Car-
  tridge Corporation. Anoka, Minnesota. Personal  communication to H. Owens,
  August 8.

Labine, P. 1978. Research Scientist, Olin Water Services, Division of Olin
  Corporation. Overland Park, Kansas. Personal communication  to B. Carson,
  July 20.

Lakings, D. 1980. Senior Bioanalytical Chemist, Midwest Research Institute.
  Personal communication to A. F. Meiners, January  27.

Lund, L. 1970. Practical Uses of Vapor Phase Inhibitors.  Proc. 3rd Euro.
  Sympo. Corrosion Inhibition, Ferrara. pp.  875-879.

Meek, J. 1978. Business Manager, Virginia Chemicals Company.  Portsmouth,
  Virginia. Personal communication to B. Carson,  August 7.

Mjos, K. 1978. Cyclic Amines. Encyclopedia of Chemical  Technology, Kirk-
  Othmer. 3rd ed. Volume 2. p. 295.

Mullins, R. M. 1978. Alkanolamines. In:  Encyclopedia of  Chemical Technology,
  Kirk-Othmer, 3rd ed., Vol. 1, p. 952.

Murphy, Mr. 1978. Industrial Boiler Treatment Section,  Combustion Engineer-
  ing. Windsor, Connecticut. Personal communication to  H. Gadberry,
  August 11.

Palm, D. 1978. Director of Regulatory Affairs, Olin Corporation Research
  Center. New Haven, Connecticut. Personal communication to B. Carson,
  August 7.

Purcell, T. E., and S. F. Whirl. 1942. Protection Against Caustic Embrittle-
  ment by Coordinated Phosphate pH Control.  Proc. 3rd Ann. Water  Conf.
  of Western Pennsylvania, pp. 45-60.

Putilova, I. N., S. A. Balexin, and V. P. Barannik. I960. Metallic Corro-
  sion Inhibitors. Pergamon Press, New York.  pp.  161-165.

Rivers, H. M., and W. M. Sonnett. 1950. Steel, Heat,  and Water. Localized
  Formation of Magnetic Iron Oxide in Power  Boilers.  Proc.  Midwest Power
  Conf., 12:114.

                                   43

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Rosenfeld (Rozenfel'd), I. L., V. P. Persiantseva,  and  M.  N.  Polteva.  1972.
  Theoretical Aspects of Metal Protection Against  Corrosion by Volatile
  Inhibitors. Proc. 4th Internat. Conv.  Metal  Corrosion, Amsterdam,  1969
  (Published in 1972 by the National Association of Corrosion Engineers,
  Houston, Texas),  pp. 606-609.

Schneider, C. 1978. Product Manager for  Triazole Products,  Sherwin-Williams
  Company, Chemicals Division. Cincinnati,  Ohio. Personal  communication to
  B. Carson, August 1.

Shell Oil Company.  1972. Shell BPI 260 Volatile Corrosion  Inhibitor. Shell
  Oil Company. Lubricants Department. Technical Bulletin 5L-72-12.

Sherwin-Williams Company. -1976.  COBRATEC -  Corrosion Inhibitors for Copper,
  Brass, Bronze, and Multi-Metal  Systems. Technical Bulletin 531.

Stevens, J. 1978. Boiler Water Product Manager, Calgon  Corporation.
  Pittsburgh, Pennsylvania. Personal communication to A. Meiners,  August 15.

Stroud, E. C., and  W. H. J. Vernon. 1952. The  Prevention of Corrosion  in
  Packaging. III. Vapor Phase Inhibitors. Journal  of Applied Chemistry 2:178-
  184.

Swift, C. 1978. American Hoechst  Corporation.  Elk  Grove Village,  Illinois.
  Personal communication to B. Carson, August  8.

Takahashi, K. 1975. Volatile Corrosion Inhibitors.  Boshaku Gijutsu 24(9):
  479-489.

Thiedke, J. 1978. Western Chemical Company,  Kansas City, Missouri.  Personal
  communication to  Howard Gadberry.

Trabanelli, G., A.  Fiegna, and V. Carassiti. 1967.  Relations Between Struc-
  ture and Inhibitor Efficiency  in the Vapor Phase. Centre Beige Etude
  et Doc. Eaux et Air. Tribune du Cebedeau  (Liege). 20(288):460-466.

Trabanelli, G., and F. Zucchi. 1976. Fundamentals  of Inhibition with VCI's.
  Proc. Nat. Assoc. Corrosion Eng. Conf. Houston,  Texas. March 22-26.
  Paper No. 82.

Uhlig, H. 1971. Corrosion and Corrosion  Control.  2nd Ed.,  John Wiley,  New York.
  pp. 270-282.

Van Sice, L. 1978.  Customer Relations Representative, Eastman Kodak Company,
  Eastman Organic Chemicals. Rochester,  New York.  Personal communication
  to B. Carson, August 1.

Van Winkle, H. 1978. Sales Manager, VCI  Paper, Daubert  Chemical Company.
  Hinsdale, Illinois. Personal communication to H.  Owens,  July 31.

                                     44

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Wachter, A., and N. Stillman. 1952. Corrosion  Inhibition  with a Mixture
  of Inhibitors of Differing Volatility. U.S.  Patent  No.  2,577,219.

Wachter, A., T. Skei, and N. Stillman. 1951. Dicyclohexylammonium Nitrite,
  a Volatile Inhibitor for Corrosion Preventive  Packaging.  Proc.  Nat.  Assoc.
  Corrosion Eng. Conf. Houston, Texas, pp. 284-294.

Walters, N. 1978. Anderson-Stolz Corporation.  Kansas  City,  Missouri.  Personal
  communication to H. Gadberry, August 15.

Webb, L. 1978. Chief of the Water  Chemistry  Section,  Black  and Veatch Engi-
  neers. Kansas City, Missouri. Personal communication to H.  Gadberry,
  August 11.

Woodward, E. R. 1958. Treating Industrial Water  with  Hydrazine. In:   Proc.
  Internat. Conf., Bournemouth, England, May 1957.  Whiffen  and Sons,  London.
  pp. 98-110.

Zisman, W. A., D. R. Spessard, and J. G. O'Rear. 1951. Noninflammable Hy-
  draulic Fluids and Lubricants. U.S. Patent No. 2,558,030. June 26.

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                                 APPENDIX A
                  PHYSICAL PROPERTIES OF VCIs.  BOILER WATER
                        AMINES AND RELATED COMPOUNDS^/
a/  Unless otherwise noted, the physical properties of these compounds were
      obtained from the Merck Index (9th Edition, 1976, published by Merck
      and Company, Inc., Rahway, New Jersey) or the Dictionary of Organic
      Compounds (4th Edition, 1965, published by Oxford University.Press,
      New York).

                                     47

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                                CONTENTS

Benzotriazole	49
Cyclohexylamine	  50
Cyclohexylammonium Carbonate	  51
Dicyclohexylamine	•  •  •  •  52
Dicyclohexylammonium Nitrite	  53
Diethanolamine	  54
2-Diethylaminoethanol 	 	  55
Diisopropylamine	  56
Diisopropylammonium Nitrite	  57
N-Ethylmorpholine	  58
Mercaptobenzothiazole	  59
Methylpropylamine	  60
Morpholine.	  61
Naphthylamine	  62
N-Nitrosodibutylaraine	  63
N-Nitrosodicyclohexylamine	  64
N-Nitrosodiisopropylamine 	 	  65
N-Nitrosodimethylamine	.66
N-Nitrosodiphenylamine.	  67
N-Nitrosomethylpropylamine	  68
N-Nitrosomorpholine 	 	  69
Octadecylamine	  70
Tolyltriazole	  71
Triethanolamine 	  72
                                      48

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BENZOTRIAZOLE
        Chemical  Formula:  C,H N
                           653
                           H

                     	.1

        Structure:
PLJ
        Molecular Weight:  119.12





        Description:  White powder





        Melting Point:  98.5°C
        Boiling Point:  bp.  = 204 C; bp0 n = 159°C
                          15      .      i *0
                   100
        Density:   d   = 1.19
        Solubility:   Soluble in alcohol, toluene,  chloroform,  DMF.

                     Slightly soluble in water.
Source:  Sherwin-Williams  (1976)
                                    49

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CYCLOHEXYLAMINE
        Chemical Formula:  C,H,-N
                            o U
        Structure:    /\   NH

                      W"   2



        Molecular Weight:  99.17




        Description:  Liquid, strong fishy amine odori




        Melting Point:  solidifies at -17.7°C
        Boiling Point:  bp_,n = 134.5°C
                          7oU
                   25
        Density:  d   = 0.8647
                            25
        Refractive Index:  n   = 1.4565
        Solubility:  Completely miscible with water and common organic

                       solvents.
                                    50

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CYCLOHEXYLAMMONIUM CARBONATE
        Chemical Formula:  c  H..N 0
                            13 26 i
                     \   V~NHC02     iH3N	\   /
Structure






Molecular Weight:   242.36




Description:  White crystals.




Vapor Pressure:  0.394 mm Hg at 25°C




Solubility:  Soluble in water, methanol and ethanol.
Source:  Stroud and Vernon (1952).
                                    51

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PICYCLOHEXYLAMINE
        Chemical Formula:  C  H  N
        Structure:







        Molecular Weight:  181.31





        Description:  Liquid, faint fishy odor





        Melting Point:  solidifies at -0.1°C, mp ~ 20°C
        Boiling Point:  bp_,.n = 256°C
                          7oU
        Flash Point:  110°C
        Density:  d 5 = 0.9104
                            25
        Refractive Index:  n   = 1.4823
        Solubility:  Slightly soluble in water; soluble in organic solvents
                                      52

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DICYCLOHEXYLAMMONIUM NITRITE (DICHAN)
        Chemical Formula:  C  H  N 0
        Structure:      \...y  ^>NH   NO
        Molecular Weight:  228.33


        Description:  White crystalline solid
        Melting Point:  173 to 180°C
                        154°C (technical product)

        Vapor Pressure:  1.2 x 10*  mm Hg at 21.0°C
        Solubility:  Slightly soluble in water; soluble in methanol,
                       ethanol
Sources:  Wachter et al. (1951); Wolfe and Temple (1948).
                                   53

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DIETHANOIAMINE
          Chemical Formula:   C^H11N02



          Structure:   (HOCH2CH2)2NH



          Molecular Weight;   105.14



          Boiling Point:   bp760 = 268.8°C



          Melting Point:   mp = 28°C



          Flash Point:   300°F


                     ?n
          Density:  d£   = 1.09664



          Dipole Moment:   2.81



          Viscosity:  V30  = 351.9 cp



          Solubility:   miscible with water,  methanol,  acetone,  very  soluble

                         in ethanol, slightly soluble  in benzene,, ether.
Source:  Weast (1976) and Toxicology Data Bank File.
                                    54

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2-DIETHYLAMINOETHANOL
        Chemical Formula:  C^H.-NO
                            D 15




        Structure:      ^>N-CH CH OH


                    C2H5


        Molecular Weight:  117.19





        Description:  Liquid
        Boiling Point:  bp_,- = 163°C
                          7oU
                   25
        Density:  d   = 0.8800
                            25
        Refractive Index:  n   = 1.4389
        Solubility:  Soluble in water, alcohol, ether, benzene,
                                     55

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DIISOPROFYLAMINE
        Chemical Formula:  C.H, _N
                            o 15
                    GH
        Structure:    3
                    CH3


        Molecular Weight:  101.19
                           /




        Description:  Liquid, characteristic odor, strongly alkaline
                          °
        Boiling Point:  84 G
                   22
        Density:  d   = 0.722
        Solubility:  Soluble in water, alcohol
                                    56

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DIISOPROPYLAMMONIUM NITRITE (DIPAN)
        Chemical Formula:  C^H, ,0 N
                            o lo z i
        Structure:    3     /^  N°2
        Molecular Weight:  148






        Melting Point:  136 to 137°G






        Vapor Pressure:  0.012 ram Hg at 20°C
Sources:  Wolfe and Temple (1948); Putilova et al. (1960),
                                      57

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N-ETHYIMORPHOLINE
          Chemical Formula:
          Structure:     0     N -
          Molecular Weight:  115.18







          Boiling Point:  bp763 = 138-139°C







          Freezing Point:  fp = 32 °C







          Melting Point:  rap = -63 °C







          Solubility:  Soluble in water, alcohol, ether, acetone, benzene.
Source:  Toxicology Data Bank File.
                                   58

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MERCAPTOBENZOTHIAZOLE
          Chemical Formula:  CyH5NS
          Structure:   |(   )l     *- SH
          Molecular Weight:  167.25


          Density:  d25 = 1.42


          Melting Point:  mp =  180.2  -  181.7
          Solubility:  Solubility at 25° (g/100 ml) in alcohol: 2.0;
                         ether: 1.0; acetone: 10.0; benzene: 1.0;
                         soluble in alkalies and alkali carbonate
                         solutions.
                                    59

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METHYLPROPYLAMINE
        Chemical Formula:  C,H, ,N
                            4 11
        Structure:  CH CH CH NHCH

                      J  £m  £-    J
        Molecular Weight:  73





        Description:  Liquid with fishy odor





        Boiling Point:  62 to 64°G
        Density:  d17 = 0.7204
        Solubility:  Soluble in water
                                      60

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MORPHOLINE
        Chemical Formula:  C. HJMO
                            4 9
                           /	\
        Structure:        0    NH
        Molecular Weight:  87.12
        Description:  Colorless hygroscopic liquid, with characteristic

                        amine odor*



        Melting Point:  -4.9°C
        Boiling Point:  bp_,,n = 128.9°C; bpf = 20.0°C
                          7oU              o
        Flash Point:  38°C
                   20
        Density:  d   = 0.994
                         20
        Vapor Density:  d,  = 1.007
        Vapor Pressure:  7.0 mm Hg at 20° C
                            20
        Refractive Index:  n   = 1.4540
        Solubility:  Miscible with water, acetone, benzene, ether, castor

                       oil, methanol, ethanol, ethylene, and glycol.
Source:  Mjos (1978),
                                     61

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NAPHTHYLAMINE§-/
          Chemical Formula:    CRN
                                10 9
          Structure:
          Molecular Weight:  143.19
          Boiling Point:
                                        a.
      - 300.8°C
      -.306.1'C
          Melting Point:
mp = 50°C
mp = 113° C
          Density:
    = 1.1229
d98 = 1.0614
 4
          Solubility:
Soluble in 590 parts
  water, freely solu-
  ble in alcohol and
  ether.
Soluble in hot water,
  alcohol, ether.
Source:  Weast (1976).

a/  The International Agency for Research on Cancer has published an evalua-
      tion of the carcinogenicity of 1-naphthylamine  (a) and 2-naphthylamine
      (3):   "Epidemiological studies have shown that occupational exposure
      to 2-naphthylamine, either alone or when present as an impurity in other
      compounds, is strongly associated with the occurrence of bladder cancer.
      There is no doubt that 2-naphthylamine is a human bladder carcinogen."
      (IARC, 1973.)

      "Exposure to commercial 1-naphthylamine containing 4-10% 2-naphthylamine
      is strongly associated with bladder cancer.   It is not possible on pres-
      ent evidence to decide whether 1-naphthylamine free of the 2-isomer is
      carcinogenic to man."  (IARC,  1973.)
                                     62

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  N-NITROSODIBUTYLAMINE -
            Chemical  Formula:    CHH10N_0
                                 o  18  L
                                  ^^CH^—CH  — CH^—CH~
            Structure:    0 =' N  -  N
           Molecular Weight:   158.28
           Description:  Pale yellow  liquid
           Boiling Point:  bp?60 = 234° -  237°C
           Density:  d20 = 9.009
           Solubility:  12% soluble in water at room temperature, miscible
                          with hexane, dichloromethane, and other organic
                          solvents.
Source:   MRI,  (1977).

a/  The  International Agency for Research on Cancer has published an evalua-
      tion  of the carcinogenicity of N-nitrosodibutylamine:  "There is suf-
      ficient evidence of a carcinogenic effect of N-nitrosodi-n-butylamine
      in several experimental animal species.  Although no epidemiological
      data  were available, N-nitrosodi-n-butylamine should be regarded for
      practical purposes as if it were carcinogenic to humans."  (IARC, 1978.)
                                      63

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N-NITROSODICYCLOHEXYLAMINE
         Chemical Formula:  C.-H^ISL
                             12 22 2
         Structure:
         Molecular  Weight:  210.36



          Description:  Crystalline needles



          Melting Point:  107°C



          Solubility:  Water solubility 0.0015 g/100 ml
Source:  Druckrey et al.  (1967)j Wolfe and  Temple  (1948)
                                    64

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N-NITROSODIISOPROPYLAMINE
        Chemical Formula:  C.FL.N.O
                            6 14 2
        Structure:    3       N-NO








        Molecular Weight:   130.22






        Boiling Point:   96°C  at  28 mm Hg






        Solubility:  Water  solubility, 1.3 g/100m^
Source:  Druckrey et al.  (1967).
                                       65

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N-NITROSODIMETHYLAMINE -
          Chemical Formula:
          Structure:   H3C
                               - NO
          Molecular Weight:   74.09
          Boiling Point:  bp,cr. = 154°C
                             /oU
                     20
          Density:  d   = 1.0048
          Refractive Index: n   = 1.4368
          Solubility:  Miscible with water, methylene chloride, vegetable
                         oils; soluble in all common organic solvents and
                         in lipids; very soluble in alcohol, ether.
Source:  Toxicology Data Bank File.

a_/  The International Agency for Research on Cancer has published an evaluation
      of the carcinogenicity of N-nitrosodimethylamine:  "There is sufficient
      evidence of a carcinogenic effect of N-nitrosodimethylamine in many ex-
      perimental animal species.  Similarities in its metabolism by human and
      rodent tissues have been demonstrated.  Although no epidemiological data
      were available, N-nitrosodimethylamine should be regarded for practical
      purposes as if it were carcinogenic to humans."  (IARC, 1978.)
                                    66

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N-NITROSODIPHENYLAMINE
          Chemical Formula:
          Structure:
                       \x_ _y /
                                t

                                N


                                0






          Molecular Weight:  198
          Description:  dark-brown solid







          Melting Point:  63 - 66°C







          Solubility:  Soluble in warm EtOH, Warm
Source:  NCI, 1979.
                                    67

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N-NITROSOMETHYLPROPYLAMINE
        Chemical Formula:  C.H,rtONL
                            4  10  2
        Structure:  CH.CH.CH^

                      3  2  S-NO
        Molecular Weight:   102
        Boiling Point:   175°C
                                      68

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N-NITROSOMORPHOLINES/
          Chemical Formula:  C H N 0
                              M- o i 2.
          Structure:       o    N-NO


          Molecular Weight:  116.1


          Description:  Yellow  Crystals


          Melting Point:   29°C
          Boiling Point:  bp y^7 = 224-225°C

                          bp6 = 96°C


          Solubility:  Miscible in water;  soluble  in  organic  solvents
Source:   IARC  (1978).
_a/  The International Agency for Research on  Cancer  has published  an  evalua-
      tion of the carcinogenicity  of N-nitrosomorpholine:   "There  is  sufficient
      evidence for a carcinogenic  effect of N-nitrosomorpholine  in several
      experimental animal  species.  Although  no epidemiclogical  data  were
      available, N-nitrosomorpholine should be regarded for practical  pur-
      poses as if it were  carcinogenic to humans."   IARC  (1978).
                                     69

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OCTADECYLAMINE
        Chemical Formula:  C  H  NH
                            lo J7  2
        Structure:  CH
                      j   z  j./




        Molecular Weight:  269





        Description:  Liquid
        Boiling Point:  bp0  _ =  172  to  173°G
                          2. »j
                                     70

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TOLYLTRIAZOLE
        Chemical Formula:  G7H7No
        Structure:
        Molecular Weight:  133.16
        Description:  off-white granules
        Density:  d    = 1.13
        Solubility:  Slightly soluble in water; soluble in methanol and
                       other alcohols.
Source:  Sherwin-Williams (1976).
                                      71

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TRIETHANOLAMINE
          Chemical Formula:
          Structure:
          Molecular Weight:  149.19





          Boiling Point: bp76Q = 335. 4°C
          Density:  d u = 1.1242
                     4
          Flash Point:  365°F
          Melting Point:  mp = 21,2°C
                             20
          Refractive Index: n'"  = 1.4852
          Viscosity:  V25 = 590.5 cp
Source:  Weast. (1976).
                                     72

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                          APPENDIX A - REFERENCES
Druckrey, H., R. Preussmann, S. Ivankovik and D. Schmahl. 1967. Organotrope
  Carcinogene Wirkungen bei 65 Verschiedenen N-Nitroso-Verbindungen an BD-
  Ratten. Zeitschrift fur Krebsforschung 69:103-201.

IARC.  1973.  International Agency for Research on Cancer.   IARC Monographs
  on the Evaluation of the Carcinogenic Risk of Chemicals to Man:  Some
  Aromatic Amines, Hydrazine and Related Substances, N-nitroso Compounds and
  Miscellaneous Alkylating Agents.  Volume 4.  International Agency for
  Research on Cancer, Lyon, France,  p. 93, 107.

IARC. 1978. International Agency for Research on Cancer. IARC Monographs on
  the Evaluation of the Carcinogenic Risk of Chemicals to Humans:  Some N-
  Nitroso Compounds. International Agency for Research on Cancer, Lyon,
  France, p. 67, 152, 275.

Mjos, K. 1978. Cyclic Amines. Encyclopedia of Chemical Technology, Kirk-
  Othmer. 3rd ed. Volume 2. p. 295.

MRI, Midwest Research Institute. 1977. Draft Report, Carcinogen Safety
  Monograph No. 2, Six Selected N-Nitrosamines. NCI Contract No. N01-CO-
  65331. p. 6 & 7.

NCI, National Cancer Institute. 1979. Bioassay of N-Nitrosodiphenylamine
  for Possible Carcinogenic!ty. NIH Publication No. 79-1720. U.S. Department
  of Health, Education, and Welfare, p. 3.

Putilova, I. N., S. A. Balexin, and V. P. Barannik. 1960. Metallic Corro-
  sion Inhibitors. Pergamon Press, New York, New York. p. 161-165.

Sherwin-Williams Company. 1976. COBRATEC - Corrosion Inhibitors for Copper,
  Brass, Bronze, and Multi-Metal Systems. Technical Bulletin 531.

Stroud, E. C., and W. H. J. Vernon. 1952. The Prevention of Corrosion in
  Packaging. III. Vapor Phase Inhibitors. Journal of Applied Chemistry
  2:178-184.

TDB, Toxicology Data Bank. National Library of Medicine.

Wachter, A., T. Skei, and N. Stillman. 1951. Dicyclohexylammonium Nitrite,
  a volatile Inhibitor for Corrosion Preventive Packaging.  Proceedings of
  the National Association of Corrosion Engineers Conference. Houston, Texas.
  pp. 284-294.

Weast, R. C. 1976. Handbook of Chemistry and Physics. Chemical Rubber
  Publishing Co. Cleveland, Ohio.

Wolfe, J. K. and K. L. Temple. 1948. The Preparation of Nitrite Salts of
  Alkyl Amines. J. Amer. Chem. Soc. 70:1414-1416.
                                       73

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                                APPENDIX B

               THE MARKET FOR AMINES AS CORROSION INHIBITORS
     A recent report by Frost and Sullivan entitled The Corrosion Inhibitors
Market estimated that 1976 expenditures for corrosion control goods and ser-
vices were $10.5 billion (Anonymous, 1978a).  Three classes of corrosion
inhibitors were considered.  The water-soluble inhibitors market in 1976
was said to be $204 million; the oil-soluble inhibitors market, $92 million;
and the vapor phase inhibitors market, $16.3 million.

     A 1975 survey by the National Association of Corrosion Engineers
(NACE, 1976) estimated that total expenditures for corrosion control were
$9.7 billion and vapor phase inhibitor purchases were $12.4 million.

     The NACE survey queried its membership about the amounts spent for
corrosion protection, including the chemical inhibitors divided into the
categories:  water-soluble, oil-soluble, and "vapor phase" inhibitors.
Table B-l presents the survey's results for the latter category.

     Miksic (1978), Chairman of the NACE task committee on volatile cor-
rosion inhibitors (T-3A-4), suspected that in most cases, boiler-water
chemicals, not VCIs, are what the NACE membership perceives as "corrosion
inhibitors, vapor phase type" (Table B-l).  Miksic recognizes that a seman-
tics problem exists and is attempting to clarify the definition of these
corrosion inhibitors within NACE.

     Attempts were made to obtain the types and quantities of the compounds
used as indicated in Table B-l with emphasis on obtaining data from indus-
tries which appear to use over 78% of the vapor phase inhibitors, i.e.,
the chemical and petrochemical industries, and the petroleum production
and refining industries.  The author of the NACE report was contacted
(Castleberry, 1979) but could not provide these data and believed that
they were not available.

     The Charles H. Kline and Company, Inc., of Fairfield, New Jersey, will
soon publish a multiclient study entitled "Refinery, Gas Conditioning, and
Pipeline Chemicals, 1978."  According to a Kline representative (Rosenberg,
1979), this 2-1/2 year survey will include information on chemical composi-
tions, quantities, market share, dollar volume, typical usage, and market
forecasts.  The survey will include refinery boiler water chemicals and
corrosion inhibitors used in pipelines.  According to the company's brochure
(Kline, 1979), most of the information in the survey appears to deal with
dollar volumes, not pounds, of chemicals, and categories of products, not
specific compounds; the only specific compounds pertinent to this study
that were noted in an outline of this study are morpholine, monoethanolamine,


                                    75

-------
             TABLE B-l.  ESTIMATED USE OF VAPOR PHASE CORROSION
                           INHIBITORS BY INDUSTRY
                                                 Amount spent on "corrosion
                                               inhibitors, vapor phase types"
Industry
Chemical and petrochemical industries
Petroleum production
Petroleum refining
Electrical utilities
Engineering and/or construction
Crude oil pipeline transmission
Natural gas transmission
Pulp and paper industry
Government
Research
Metals industry
Nuclear power industry
Equipment manufacturing industries
Gas utilities
Water utilities
Communications
Other industries

Dollars
(millions)
4.012
3.199
2.482
0.396
0.281
0.263
0.237
0.208
0.158
0.114
0.105
0.079
0.057
0.003
0.000
0.000
0.789
12.383

a/
Percentr-
32.4
25.8
20.0
3.2
2.3
2.1
1.9
1.7
1.3
0.9
. 0.8
0.6
0.5
0.0
0.0
0.0
6.4

a./  Figures may not total 100% due to rounding.

Source:  NACE, 1976.
                                     76

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and diethanolamine; of these, only morpholine is used extensively as a
boiler water additive.  The absence of other volatile amines from the
outline confirms our opinion that the "vapor phase types" of corrosion
inhibitors listed by NACE  (Table B-l) as used by the "petroleum refining,"
"natural gas transmission," and "crude oil pipeline transmission" indus-
tries are indeed boiler water additives, and not VCIs.

     A partial summary of  the information compiled by Kline and Company
is presented in Table B-2.

     A comparison of the estimates made by Kline and by NACE shows some
important discrepancies (Table B-3).  As indicated in the table, major
differences occur in estimates of the amounts of corrosion inhibitors
used:  (a) to treat water  in refinery operations and (b) in petroleum and
gas transmission operations.

     Perhaps the major reason for these discrepancies is that each estimate
was based to a large extent upon personal knowledge and opinion obtained
via interviews.  Another problem is the fact that boiler water amines are
commonly sold to the user  at a price which includes in-plant corrosion  .
control service (Ward, 1979).

     The size of the discrepancies in dollar volume obtained in these two
extensive and detailed surveys provides an indication of how time-consuming
and difficult it would be  to obtain reliable information concerning the
quantities and types of chemicals used.  Rosenberg (1979), who is participat-
ing in the Kline and Company survey, estimated that a minimum of 200 inter-
views, including some on-site visits, would be required in order to obtain
even a rough estimate of the chemicals used and their amounts.  He also
stated that the end users  of the inhibitors would not be very helpful
mainly because they do not know the composition of the products they use.

     Frost and Sullivan, Inc., New York, New York, published a report
in 1978 entitled "Corrosion Inhibitors Market."  According to their cata-
log, this report provides  a forecast of the corrosion inhibitor market,
including markets for boilers, oil well, and refinery operations.  In this
report, as well as the Kline and Company survey, the emphasis appears to
be placed on dollar amounts of products sold and not pounds of chemicals
used.

Personal Interviews

     Knowledgeable representatives of the following chemical and petro-
chemical industries were contacted concerning volatile amines used as cor-
rosion inhibitors.
                                     77

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TABLE B-2.  ESTIMATED U.S. SALES OF CHEMICALS AND
              FORMULATED CHEMICAL SPECIALITIES IN
              REFINING, GAS CONDITIONING,  AND
              PIPELINE TRANSMISSION, 19771/
    Use category
Millions of dollars
Refining
  Water treatment
    Corrosion inhibitors
    Other chemical products

  Processing
    Corrosion inhibitors
    Other chemical products
Gas conditioning
  Ethanolamines
  Other chemical products
         $  30
         	52
           82

           15
         	16
 Total   $113
         $  30
                               Total   $  57
Pipeline transmission
  Petroleum
    Corrosion inhibitors
    Other chemical products

  Gas
    Corrosion inhibitors
    All other
                               Total
                         Grand total
         $  15
         	18
         $  33

         $  15
         	2
         $  17
         $  50
         $220
Source:  Kline (1979)

a/  Excludes service.
                         78

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 TABLE B-3.   COMPARISON OF  NACE AND KLINE  SURVEYS CONCERNING CORROSION
               INHIBITORS (MILLIONS OF  DOLLARS)
                         Kline estimate
                           (for 1977)
                                             NACE estimate
                                              (for 1975)
 Refining
   Water treatment
   Processing
 Pipeline transmission
                        Total
                        30
                        11
                        45
 2.4 ("vapor phase types")

"32
Petroleum
Gas
15
15
Total 30
9.4 (0.26 "vapor phase types")
4.9 (0.24 "vapor phase types")
14.3

 Sources:.  Kline  (1979); NACE  (1976).
     y-
     *
     *
     *
     *
Union Carbide, Tarrytown, New York
Du Pont, Wilmington, Delaware
Dow Chemical, Midland, Michigan
Standard Oil Company, Sugar Creek, Missouri
Amoco Research, Naperville, Illinois
Shell Oil Company, Houston, Texas
Gulf Oil Company, Houston, Texas
Texaco, Inc., White Plains, New York
     In general, these representatives know of no large-scale uses by their
industry group of volatile amines as corrosion inhibitors except in boiler
operations.  They also were not knowledgeable of exactly what compounds were
contained in the boiler water chemicals, other than that they were neutral-
izing or film-forming amines.
                                    79

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                         APPENDIX B - REFERENCES
Anonymous. 1978a. Corrosion. Inhibitor Market  Expected  to Double to $24 Bil-
  lion by Year 1985. Chemical Marketing  Reporter.  213(8).  February 20. pp.
  5, 21.

Castleberry, J. 1979. Author, National Association of  Corrosion Engineers
  NACE) Survey, 1976. Personal  Communication  to  Ms.  M.  Simister. May 24.

Kline. 1979. Refinery, Gas  Conditioning,  and  Pipelines  Chemicals 1978.
  Charles H. Kline  & Co.,  Inc.,  Fairfield,  New Jersey.

Miksic, B. A. 1978.  President,  The  Cortec Corporation.  St. Paul, Minnesota.
  Personal communication to A.  Meiners,  July  13.

NACE. 1976. National Association of Corrosion Engineers. Corrosion - A
  Devastating Problem that  is Costing U.S.  Industries  $Billions Each Year.
  Houston, Texas.

Rosenberg, L., 1979. Project Manager, Charles H.  Kline  & Co., Inc. Fairfield,
  New Jersey. Personal communication to  Ms. Mary Simister, May 24.

Ward, ¥. 1979. Director of  Technology, Olin Water Services Division, Olin
  Corporation, Overland Park, Kansas. Personal communication to A. F. Meiners,
  August 14.
                                     80

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                                APPENDIX C

            REVIEW OF POSSIBLE NITROSAMINE FORMATION REACTIONS
                      OF VCIs AND BOILER WATER AMINES
     The most likely possibility as a source of nitrosamines from VCIs
and boiler water amines is the nitrosation of secondary amines.  All of
the VCI amines presently used are secondary amines, and about one-third
of the neutralizing amines are secondary amines.  However, cyclohexylamine
and octadecylamine are primary amines which represent major fractions of
the market for neutralizing and filming amines, respectively (see text,
p. 34).  In addition, 2-diethylamirioethanol is a tertiary amine which rep-
resents 10 to 20% of the market for neutralizing amines (see text,  p.  34).

     Edwards et al. (1978) have reported that "contrary to popular belief,
not only secondary amines, but also primary and tertiary amines can all
yield IJ-nitroso compounds."

     Discussed below are the reactions which could produce nitrosamines
from VCIs and boiler water amines.

Nitrosation of Secondary Amines

     The classic method for producing nitrosamines is the interaction of
secondary amines with nitrous acid; in practice, the method consists of
acidifying a solution containing a nitrite salt and. a secondary amine
(Mirvish, 1975).


          RRNH + N0~ + H   - >   RN-NO + H0
     In the acid-catalyzed nitrosation of secondary amines, nitrite is
usually first converted to nitrous acid, which in turn is  converted to  an
active nitrosating species:  nitrogen (III)  oxide (^O-j) ,  nitrous acidium ion
(H2N02+), nitrosyl cation (NO1), nitrosyl thiocyanate (ON-NCS ), or nitrosyl
halide (NOX ) (Olajos and Coulston, 1978).  The nitrogen (III) oxide moiety
(N203 ^  > NOo'NO') is the active nitrosating agent in the pH range 1 to 4;
at the dilute acidic conditions that are encountered in the environment,
this moiety is likely the one which nitrosates secondary amines (Fine,
1979).

     The N-nitrosation of secondary amines is usually very slow at neutral
or alkaline pH because of the low equilibrium concentration of nitrous an-
hydride.  However, in the presence of formaldehyde,  chloral (Keefer and
Roller, 1973), or some metal ions, appreciable nitrosation can occur even
at pH 6 to 11 (Fine, 1979).
                                    81

-------
       In  pure  buffered  aqueous  systems,  dimethylamine in the presence of
 nitrite was  not  nitrosated  at pH values  above 5»0j  however,  in sterilized
 soil  and  sewage  samples,  nitrosation was observed to occur at pH values as
 high  as 7.7  (Mills  and  Alexander, 1976).

      Nitrosation can take place by other reactions;  for  example  dimethyl-
 and diethyl-nitrosamines  are evidently formed in  air by  the  reaction of
 nitrogen  oxides  with the  secondary amines (Fine and  Rounbehler,  1976).
 The nitrosating  agent can be nitrogen (II)  oxide  (NO), nitrogen  (IV)
 oxide (NO'    .N20 ), or nitrogen (III) oxide  (N20 ), (Edwards et al.,
 1978).  Nitrogen "(II) oxide (NO)  itself  has been  shown to be a poor
 nitrosating  agent (Challis  and  Kyrtopoulos, 1976).   However, nitrosation
 in the presence  of  NO and air proceeds readily, presumably because  of
 oxidation of some of the  NO to  N02 and the  formation of  NjO^ from NO
 and N0_.  Nitrosation by  N20  and N_0, proceeds rapidly  at room  tempera-
 ture  in aqueous  solution  at a pH in the  range of  6  to 14. The reactions
 are very  much  faster than those with acidified nitrite  (Challis  et  al.,

      Pitts et  al.  (1978)  have reported studies of the nitrosation of diethyl-
 amine in  air containing ambient levels of NO  and  N02«  Diethylatnine is  rap-
 idly  nitrosated  in  the  dark but is subsequently  destroyed by sunlight.

      Fan  et  al.  (1978)  have recently shown  that certain  C-nitro  compounds-
 can readily  nitrosate secondary amines to form N-nitroso compounds.  C-nitro
 compounds are  widely used as pesticides,  bactericides, coloring  agents,
 drugs, and perfumes  (Fine,  1979).   The reaction occurs rapidly at neutral
 and alkaline pHs, but alkaline  conditions are the most favorable (Fine,
 personal  communication, 1978).

      Transnitrosation of  aliphatic secondary  amines  has  also been demon-
 strated to occur  (Singer  et al.,  1978).   Transnitrosation is the transfer
 of the nitroso group of one N-nitrosamine to  another amine to form  a dif-
 ferent N-nitrosamine.
          R^N-NO + R3R4NH2   	-> R R^N-NO +


Many transnitrosation reactions are known to take place in strong aqueous
acid (pH 1.5) and the reactions are catalyzed by nucleophiles such as thio-
cyanate or halide ion.  Some secondary amines are more easily nitrosated by
this reaction than others; for example, morpholine can apparently be readily
nitrosated by a variety of nitrosamines (Fine, 1978).  Also, some nitrosa-
mines appear to be stronger nitrosating agents than others (Singer et al.,
1978).
a/  A C-nitro compound is a compound in which a nitro group  (N02 ) is
      attached to an aliphatic carbon atom.

                                     82

-------
     The nitrosation of secondary amines by microorganisms at pH values
 above  5.0 has been reported by several investigators  (Archer et al.,  1978).
 Rate enhancements of from  12-  to 49-fold  have been observed  when  dihexylamine
 was nitrosated at pH 3.5 in the  presence of bacteria  and yeast cells; a non-
 enzymatic mechanism is proposed  (Archer et al., 1978).

     Very little has been reported concerning the  potential transformation
 to nitrosamines of secondary amines used as VCIs or boiler water additives.
 N-nitrosomorpholine has been detected on one occasion in the steam emissions
 from boilers  (see text, p. 36).  However, the morpholine added to the boiler
 is not believed to be the source of the nitrosamine.  Dichan, the nitrite
 salt of a secondary amine, apparently can be at least partially transformed
 to the corresponding nitrosamine (see text, p.  21).

 Nitrosamines from Primary and Tertiary Amines

     Although the nitrosation of secondary amines has been studied exten-
 sively, there are relatively few publications concerning the formation of
 nitrosamines from primary and tertiary amines.

     The nitrosation of primary amines yields monoalkylnitrosamines which
 are highly unstable (Olajos and Coulston, 1978).  However, small quantities
 of secondary amine N-nitroso compounds are also formed in this reaction via
 a mechanism which is not well understood (Fine, 1979).

     Tertiary amines react with nitrous acid to yield amine type N-nitroso
compounds.  Erroneous reports to the contrary have persisted for over 100
 years  (Fine, 1979).  The reaction involves a nitrosative dealkylation; an
 alkyl group must first be cleaved oxidatively to yield the secondary  amine,
which then becomes nitrosated.  The mechanism of this reaction has been
discussed by Lijinsky et al. (1972).

     No reports were found concerning the formation of nitrosamines from
primary or tertiary amines used as boiler additives.
                                     83

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                         APPENDIX C -  REFERENCES
Challis, B. C., and S. A. Kyrtopoulos.  1976.  Mitrosation under Allealine
  Conditions. J. C. S. Chem.  Comm.  178.

Challis, B. C., A. Edwards, R.  Hunma,  S.  A.  Kyrtopoulos,  and J. R.  Outram.
  1978. Rapid Formation of N-Nitrosamines from Nitrogen Oxides under Neutral
  and Alkaline Conditions. Environmental  Aspects  of  N-Nitroso Compounds,
  by E. A. Walker, M. Casteguaro, L. Griciute,  and R.  E.  Lyle. International
  Agency for Research on Cancer, Lyon,  France.  Scientific Publication No.
  19. pp. 127-142.
                          x.
Edwards, G., I. Krull, M. Wolf,  and D.  Fine.  1978. N-Nitroso Compounds in
  the Air Environment. Presented before the  Division of Environmental Chemis-
  try, American Chemical Society. Anaheim, California. March 12-17.

Fan, T. Y., R. Vita, and D. H.  Fine. 1978. C-Nitro Compounds:  A New Class
  of Nitrosating Agents. Toxicology Letters  2:5-10.

Fine, D. H. 1979. N-Nitroso Compounds  in  the Workplace. Monitoring Toxic
  Substances, by D. Schuetzle.  American Chemical  Society Symposium Series
  No. 94. pp. 247-254.

Fine, D. H. 1978. Thermo Electron Corporation.  Waltham, Massachusetts. Per-
  sonal communication to A. Meiners, August  15.

Fine, D. H., and D. P. Rounbehler.  1976.  N-Nitroso Compounds in the Ambient
  Community Air of Baltimore, Maryland. Analytical Letters 9(6):595-604.

Keefer, L. K., and P. P. Roller. 1973.  N-Nitrosation by Nitrite Ion in Neu-
  tral and Basic Medium. Science 81:1245-1247.

Lijinsky, W., L. Keefer, E. Conrad, and R. Vande  Bogart.  1972. Nitrosation
  of Tertiary Amines and Some Biologic Implications. Journal of the National
  Cancer Institute. 49:1239-1249.

Mills, A. L., and M. Alexander.  1976.  Factors Affecting Dimethylnitrosamines
  Formation in Samples of Soil  and  Water. Journal of Environmental Quality
  5(4):437-440.

Mirvish, S. S. 1975. Formation  of N-Nitroso  Compounds:  Chemistry,  Kinetics,
  and In Vivo Occurrence. Toxicology and  Applied  Pharmacology 31:325-351.
                                    84

-------
Olajos, E. J., and F. Coulston. 1978. Comparative  Toxicology of  N-Nitroso
  Compounds and their Carcinogenic Potential  to  Man.  Ecotoxicology and En-
  vironmental Safety 2:317-367.

Pitts, J. N., Jr., D. Grosjean, K. Van  Cauweriberghe,  J.  B.  Schmid, and D.
  R. Fitz. 1978. Photooxidationof Aliphatic Amines under Simulated Atmos-
  pheric Conditions:  Formation of Nitrosamines, Nitramines, Amides,  and
  Photochemical Oxidant. Environmental  Science and Technology 12(8):946-
  953.

Singer, S. S., W. Lijinsky, and G. M. Singer. 1978.  Transnitrosation:  An
  important Aspect of the Chemistry of  Aliphatic Nitrosamines.  Environmental
  Aspects of N-Nitroso Compounds, by E. A. Walker, M.  Castegnaro, L.  Gricuite,
  and R. E. Lyle. International Agency  for Research  on Cancer,  Lyon,  France.
  Scientific Publication No. 19. pp. 175-182.
                                    85

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                                 APPENDIX D


   MARKET INFORMATION ON SELECTED COMPOUNDS USED FOR CORROSION INHIBITION^

  Compound (CASRN)!/         Manufacturer       1977 Production (Ib)   Importer

Benzotriazole           Fairmount Chemical Co.       0 to 1,000          No
syn:  iH-Benzotriazole
(95-14-7)               Columbia Organic             0 to 1,000          No
                          Chemicals

                        Agfa-Gevaett                      0              Yes

                        The Sieflor Corp.       "small manufacturer"     Yes

                        Sherwin Williams           "manufacturer"        No
                          Chemicals

                        Mobil Oil Corp.              0 to 1,000          Yes

                        Unknown!/                         0              No

Cyclohexylamine         Drew Chemical Corp.       10,000 to 100,000      Yes
syn:  Cyclohexanamine
(108-91-8)              Mobay Chemical Corp.
                          New Martinsville, W.Va.   "manufacturer"        No

                          Pittsburgh, Penn.      not a manufacturer      Yes

                        American Hoechst Corp.            0              Yes

                        Thorson Chemical Corp.      0 to 1,000           Yes

                        The Sieflor Corp.       "small manufacturer"     Yes

                        Sandoz Colors & Chemi-            0              Yes
                          cals - N. J.

                        Unknown!/                   0 to 1,000           Yes
                                 (continued)
                                      87

-------
                           APPENDIX D (continued)
Compound (CASRN)-'
                             Manufacturer
                        1977 Production (Ib)  Importer
Cyclohexylamine (con-
  tinued)
I. Schneid Inc., Ga.

Machemco Inc.

Chemical Exchange Co.,
  Inc.

E. I. du Pont
  Victoria, Tex.
     \
  Orange, Tex.
                                                 "manufacturer"

                                                 "manufacturer"

                                                 100 million to
                                                  500 million^-/


                                                 1,000 to 10,000

                                                10,000 to 100,000
                        Virginia Chemicals Inc.,   "manufacturer"
                         - Portsmouth
                        C. Itoh and Co., Inc.

                        Abbott Laboratories

Dibenzylamine           Uniroyal Chemical Divi-
syn:  Benzenemethana-     sion, Uniroyal Inc.
        mine,
      N-(phenylmethyl)- Miles Laboratories Inc.,
(103-49-1)                Sumner Division

                        .Hexcel Corp., Specialty
                          Chemicals Division

                        The Ames Laboratories
                          Inc.

Dicyclohexylamine       Kodak Park Division
syn:  Cyclohexanamine,
      N-cyclohexyl-     BASF Wyandotte Corp.
(101-83-7)
                        American Hoechst

                        Virginia Chemicals, Inc.
                          Portsmouth

                        Koch Chemical Co.

                                  (continued)

                                       88
                                  0

                           "manufacturer"

                             0 to 1,000


                           "manufacturer"


                           "manufacturer"


                             0 to 1,000


                             0 to 1,000

                                  0



                            "manufacturer"


                         not a manufacturer
No

No

No



No

No

No


Yes

No

No


No


No


No


No

Yes

Yes

No


Yes

-------
                            APPENDIX D (continued)
  Compound (CASRN)-/
                             Manufacturer
 1977 Production (Ib)  Importer
Dicyclohexylamine
  (continued)
                        Abbott Laboratories
Dicyclohexylammonium    Olin Corp.
  Nitrite
syn:  Cyclohexanamine,  Northern Instruments
      N-cyclohexyl-,      Corp.
      nitrite
(3129-91-7)
    "manufacturer"


   10,000 to 100,000

    1,000 to 10,000
Diethylamine
s yn:  E thanamine,
      N-ethyl-
(109-89-8)
2-Diethylaminoethanol
syn:  Ethanol,
      2-(diethylami-
      no)-
(100-37-8)
                        Ashland Chemical Co.
                          International Division

                        Pennwalt Corp.

                        BASF Wyandotte Corp.
           0


    "manufacturer"

   10,000 to 100,000
                        Air Products & Chemicals
                          Inc.
                          Pace, Fla.               "manufacturer"
                          St. Gabriel, La.

                        Uniroyal Chemical Divi-
                          sion, Uniroyal Inc.

                        Virginia Chemicals, Inc.
                          Portsmouth

                        Penwalt Corp.

                        Haven Chemical

                        Union Carbide Corp.

                        Alcolac Inc.

                        SST Corp.

                        The Ora Corp.
                                                   "manufacturer"
    "manufacturer"


    "manufacturer"

 "small  manufacturer"

    "manufacturer"

    "manufacturer"

      0 to 1,000

1 million to 10 million
                        Proctor Chemical Co.,  1 million to 10 million
                          Inc.
                                 (continued)

                                      89
No


No

No
Yes


No

Yes



No

No

Yes


No


No

No

No

No

Yes

No

No

-------
                            APPENDIX D (continued)
  Compound (CASRN).2-/
     Manufacturer
                        1977 Production (Ib)  Importer
2-Diethylaminoethanol   ICI Americas Inc.
  (continued)
                        Unknowns.'
                           1,000 to 10,000       Yes

                        "small manufacturer"     No
Diisopropylamine
syn:  2-propanamine
      N-(l-methyleth-
      yD-
(108-18-9)
Methylpropylamine
syn:  2-butanamine
(13952-84-6
Morpholine
(110-91-8)
Pennwalt Corp.

Union Carbide Corp.

Air Products & Chemi-
  cals Inc.

ICI Americas Inc.
                           "manufacturer"
                           "manufacturer"
                           "manufacturer"
                               o /
                        Unknown^-'
                         not a manufacturer

                             0 to 1,000

BASF Wyandotte Corp.              0

American Hoechst Corp.            0
No

No

No


Yes

No

Yes

Yes
                        E. I. du Pont de
                          Nemours & Co.
                       1 million to 10 million^' No
                        Virginia Chemicals, Inc.,  "manufacturer"
                          Portsmouth
Henkel, Inc.

Henley & Co., Inc.

Union Carbide Corp.

BASF Wyandotte

ABC Compounding Co.,
  Inc.
                             0 to 1,000
                                                 No
Yes
                                                 not a manufacturer      Yes

                                                          0              No

                                                100,000 to 1 million     Yes

                                                  1,000 to 10,000        No
                        American Bio-Synthetics  "small manufacturer"—'   No
                          Corp.
                        Jefferson Chemical Co., Inc.
                          Port Neches, Tex.         "manufacturer"
                          Conroe, Tex.
                                 (continued)
                           "manufacturer"
                                                 No

                                                 No
                                      90

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                           APPENDIX D  (concluded)
                  o /
  Compound  (CASRN)—'         Manufacturer       1977 Production  (Ib)  Importer
                                o /
Morpholine  (continued)  Unknown^'               "small manufacturer"     No

N-Nitrosodiisopropyla-  Kodak Park Division               0              No
  mine
syn:   1-propanamine,    The Ames Laboratories        0 to 1,000          No
      N-nitroso-n-        Inc.
      propyl-
(621-64-7)

Octadecylamine          Armak Industrial Chemicals
syn:  1-octadecylamine    McCook, 111.              "manufacturer"        No
(124-30-1)
                          Morris, 111.              "manufacturer"       NO

                        Ashland Chemical Company
                          Oakland, Calif.                 0              No

                          Mapleton, 111.        100,000 to 1 million     No

                        I. Schneid Inc., Ga.        "manufacturer"        No

                        Machemco Inc.               "manufacturer"        No

                        General Mills Chemicals     "manufacturer"        No
                          Inc.

                        Unknown!/                   1,000 to 10,000       Yes

Tolyltriazole           American Hoechst Corp.   not a manufacturer      Yes
syn: lH-Benzotriazole,
     methyl             Sherwin Williams            "manufacturer"        No
(29385-43-1)              Chemicals

I/  Based on nonconfidential information submitted  to the EPA by manufacturers
    and importers as of January, 1979.

2j  Chemical Abstracts Service Registry Number.

_3_/  Link between information and company has been claimed to be  confidential. .

4/  Chemical is manufactured and consumed on site.
                                     91

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                                          TECHNICAL REPORT DATA
                                 ll'leasc read luuructions on the reverse he fore completing!
 1  REPORT NO.
  EPA 560/11-80-023
 •1. TITLE AND SUB! I'l LIE
  Volatile Corrosion  Inhibitors and Boiler  Water
  Additives:   Potential  for Nitrosamine Formation
                6. PERFORMING ORGANIZATION CODE
                                                                      3. RECIPIENT'S ACCESSION NO.
                5. REPORT DATE
                  July  1980
 7. AUTHORISi
  Alfred  F. Meiners,  Howard Gadberry,  Bonnie L.  Carson
  Harold  P. Owens,  Thomas  W. Lapp
                                                                      8. PERFORMING ORGANIZATION REPORT NO.
 9. PERFORMING ORGANIZATION NAME AND ADDRESS
  Midwest Research Institute
  425 Volker  Boulevard
  Kansas  City,  Missouri   64110
                10. PROGRAM ELEMENT NO.
                  Task  III
                11. CONTRACT/GRANT NO.
                                                                        68-01-3896
 12. SPONSORING AGENCY NAME AND ADDRESS
  Environmental Protection Agency
  Office  of  Pesticides and Toxic Substances
  Washington,  D.C.   20460
                13. TYPE OF REPORT AND PERIOD COVERED
                  Final  Rpnnrf-	
                          Len
                          INTO
                14. SPONSORING AGENCY CODE
 15. SUPPLEMENTARY NOTES
  Roman  Kuchkuda,  Project  Officer
 16. ABSTRACT
                         Study investigated volatile corrosion inhibitors (VCIs) and the use of
             amines  as boiler water additives.  The major VCI's are  dicyclohexylammoniuni  nitrite
             (Dichan), "nonnitrite" Dichan substitutes,  and'benzotriazole.  The  present market is
             about 310^000 kg/year; over 90% of the use  is in the preparation of impregnated paper
             and other wrapping materials. Dichan can be converted  to the corresponding nitrosa-
             mine; commercial products can contain up to 1 ppm of the nitrosamine. Nonnitrite sub-
             situtes are less likely to be converted to  nitrosamines but can likely be readily
             nitrosated under environmental conditions.  Benzotriazole Is likely to be environmen-
             tally stable and not converted to the corresponding nitrosamine.  Population exposure
             to VCI's is large since it is estimated that over 20 million individual items are
             wrapped in VCI impregnated paper.  Two cases of nitrosamine detection at levels of
             100 and 90 ppm in VCI wrapping paper have been reported.  A number  of amines are em-
             ployed  for treating boiler water.  The total market in  1978 was estimated to be 9,000
             to 10,300  metric tons.  The two most widely used neutralizing amines are cyclohexyl-
             amine and morpholine; octadecylamine is the most common film-forming araine.   There is
             no experimental evidence to indicate whether or not nitrosamines are formed in boilers
             as a result of the addition of these amines.  Picogram  amounts of N-nitrosomorpholine
             were recently reported in the steam condensate from boilers and at  several other lo-
             cations at a plant which produces chemicals for the rubber industry.  It was specu-
             lated that a transnitrosation reaction of morpholine with N-nitrosodiphenylamine may
             have resulted in the N-nitrosomorpholine.
                                      KEY WORDS AND DOCUMENT ANALYSIS
                     DESCRIPTORS
  Corrosion Inhibition
  Nitrosamines
  VCI
  Exposure
  Boiler Additives
  Water Treatment
                                                       b.lDENTIFIERS/OPEN ENDED TERMS  C.  COSATI Field/Group
 Z. DISTRIBUTION STATEMENT

  Unlimited distribution
19. SECURITY CLASS (This Report I
   Unclassified
21. NO. OF PAGES
      95
                                                      20. SECURITY CLASS (This page)
                                                         Unclassified
                                                                                      22. PRICE
EPA Form 2220-1 (9-73)
                                                    92

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