Scientific Publications and Patents Joseph Seifter, M.D. Pioneer in the development of pharmacology and toxicology in the United States. Senior Medical Advisor to the Director of the Office of Toxic Substances U.S. Environmental Protection Agency Gold Medalist 1904-1982 ------- SCIENTIFIC PUBLICATIONS AND PATENTS JOSEPH SEIFTER, M-D- Compiled By Roberta E. Heisler OPTS Technical Information Center Information Support Services Branch Management Support Division Office of Toxic Substances Washington, DC 20460 OFFICE OF PESTICIDES AND TOXIC SUBSTANCES U.S. ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460 April 1983 ------- INTRODUCTION Dr. Joseph Seifter, eminent colleague, scholar in pharmacology and medicine, and valued member of the U.S. Environmental Protection Agency's Office of Toxic Substances, left behind a legacy of valuable research. In tribute, this bibliography of publications and patents, which spans Dr. Seifter's career, was compiled. Copies of the works listed are located in the Office of Pesticides and Toxic Substances (OPTS) Technical Information Center (Rm. E447, Phone: 202- 382-3529). Special thanks is given to Dr. Joseph P. Hanig, U.S. Food and Drug Administration; Geraldine Nowak, U.S. EPA OPTS Technical Information Center; and Douglas Sellers, U.S. EPA OPTS Information Support Services Branch for identification, organization, and retrieval of the publications and patents in this bibliography. ------- TABLE OF CONTENTS Introduction ii Collection of: Papers 2 Monographs and Excerpts 20 Abstracts 22 Patents 29 Journal Abbreviation Index 33 Subject Index 36 ------- COLLECTION OF PAPERS ------- PAPERS *P# AUTHORS TIT IE JOURNAL YEAR VOL. PAGE 1 . 2. 3. 4. 5. 6. 7. 8. 9. Tor a Id Sollmann Joseph Seifter Joseph Seifter Joseph Seifter Joseph Seifter Harry R. Trattner Joseph Seifter L. Pillemer A.O. Kuhn E.E. Ecker Joseph Seifter L. Pillemer Joseph Seifter E. Ecker L. Pillemer Joseph Seifter E. Ecker A. Pa ley Joseph Seifter The Pharmacology of Trimethyl Bismuth Pharmacology of Metal Alkyls II. Trimethylstibine Yields of Stibines and Arsines Simplified Qualitative Analysis of Urinary Calculi by Spot Tests Vitamin C in Chronic Lead Poisoning Pharmacologic Action and Chemical Constitution in the Barbiturate Series The Effect of Amino Compounds on the Fourth Component of Complement The Effect of Reducing Agents on the Fourth Component of Complement Treatment of Experimental Hydrofluoric Acid Corrosion J. Pharmacol. Exp. Ther. J. Pharmacol. Exp. Ther. J. Am. Chem. Soc. J. Urol. Am. J. Med Sci. Reserve Pharmacon J. Enmunol. J. Immunol. Proc. Soc. Exp. Biol. Med. 1939 67 17-49 1939 66 366-377 1939 61 530-531 1939 42 452-457 1940 200 322-327 1941 1 4-5, 11 1941 40 89-95 1941 40 97-99 1941 46 190-192 * "P" denotes paper -2- ------- *Pt AUTHORS TITLE JOURNAL YEAR VOL. PAGE 10. Torald Sollmann Joseph Seifter 11. Joseph Seifter E.S. Rambousek 12. Joseph Seifter Frank M. McDonald 13. Joseph Seifter 14. Joseph Seifter 15. Albert J. Gilbert Joseph Seifter 16. Paul Gyorgy Joseph Seifter R.M. Tomarelli Harry Goldblatt 17. Joseph Seifter W.E. Ehrich George Hudyma George Mueller 18. Nancy V. Clymer Joseph Seifter 19. Wm. E. Ehrich Joseph Seifter Intravenous injections of Soluble Bismuth Compounds: Their Toxicity and Their Sojourn in the Blood and Organs J. Pharmacol. Exp. Ther. 1942 74 134-154 Intravenous injection of Soluble Tin Compounds J. Lab. Clin. Med. 1943 28 1344-1348 Urinary Excretion of Bismuth Following Large But Nonfatal Dose of Bismuth Subsalicylate Liver Injury in Dogs Exposed to Trichloroethylene An Unusual Action of Amphetamine A Note on the Unsuitability of Guinea Pig jejunum for Study by the Magnus Method Influence of Dietary Factors and Sex on the Toxicity of Carbon Tetrachloride in Rats Thyroid Adenomas in Rats Receiving Selenium A Method of Screening Sympathomimetic Amines for Stimulant Action on the Cerebrum Role Played by the Salivary Glands in the "Alarm Reaction" J. Am. Med. Assoc. 1943 123 149 J. Bid. Hyg. Toxicol. Science J. Lab. Clin. Med. J. Exp. Med. Science J. Pharmacol. Exp. Ther. Arch Pathol. 1944 1945 1946 1946 1946 1947 1948 26 250-252 102 31 597 372 83 499-562 103 2687 89 149-152 45 239-245 * "P" denotes paper -3- ------- *Pt AUTHORS TITLE JOURNAL TEAR VOL. PAGE 20. Joseph Seifter Wm. E. Ehrich 21. Sam Seifter David M. Harkness Edward Muntwyler Joseph Seifter 22. Wm. E. Ehrich Joseph Seifter 23. George H. Warren Edwin C. Williams Harvey E. Alburn Joseph Seifter 24. Wm. E. Ehrich Joseph Seifter Harvey E. Alburn Albert J. Begany 25. Wm. E. Ehrich Joseph Seifter 26. Carolyn Forman Joseph Seifter Wm. E. Ehrich 27. Joseph Seifter Wm. E. Ehrich 28. C.W. Sorenson Joseph Seifter I.S. Wright Goitrogenic Compounds: Pharmacological and Pathological Effects The Effect of Dithiobiuret on the Electrolyte and Water Content of Skeletal Muscle, and on Carbohydrate Metabolism Experimental Serum Disease: A Pathogenetic Study Rous Chicken Sarcoma as a Source for Hyaluronic Acid Heparin and Heparinocytes in Elephantiasis Scroti Thrombotic Thrombopenic Purpura Caused by Iodine Effects of Salicylates and Other Drugs on Experimental Serum Disease Effects of Prolonged Administration of Antithyroid Compounds on the Thyroid and Other Endocrine Organs of the Rat A New Synthetic Anticoagulant (Heparinoid): Preliminary Report of Its Action in Humans J. Pharmacol. Exp. Ther. J. Pharmacol. Exp. Ther. J. Exp. Med. Arch. Biochem. 1948 92 303-314 1948 93 93-100 Proc. Soc. Exp. Biol. Med. Arch. "Pathol. J. Allergy Arch. Pathol. Bull. N.Y. Acad. Med. 1949 89 23-26 1949 20 300-304 1949 70 183-184 1949 47 446-449 1949 20 273-285 1949 48 536-547 1949 25 448 * "P" denotes paper -4- ------- *P# AUTHORS TITLE JOURNAL YEAR VOL. PAGE 29. Joseph Seifter David H. Baeder Alphonse Dervinis 30. Joseph Seifter David H. Baeder Albert J. Begany 31. Joseph Seifter Peter J. Warter Donald R. Fitch Alteration in Permeability of Some Membranes by Hyaluronidase and Inhibition of this Effect by Steroids Influence of Hyaluronidase and Steroids on the Permeability of Synovial Membrane Preliminary Observations on the Antiarthritic Effect of 2,1-Acetoxy-pregnenolone Proc. Soc. Exp. 1949 Biol. Med. 72 136-141 Proc. Soc. Exp. Biol. Med. 1949 72 277-282 Proc. Soc. Exp. 1950 Biol. Med. 73 131-134 32. Joseph Seifter Donald R. Fitch David H. Baeder Albert J. Begany 33. George H. Paff Joseph Seifter 34. Joseph Seifter 35. Joseph Seifter George H. Warren 36. Joseph Seifter Wm. E. Ehrich Albert J. Begany George H. Warren 37. Joseph Seifter The Action of Hyaluronidase and Steroids on Membrane Permeability The Effect of Hyaluronidase on Bone Growth In vitro Studies on the Pharmacology and Toxicology of Testicular Hyaluronidase Effect of Purified Hyaluronidase on Growth Sarcoma 37 in the Mouse Effect of Cortisone, Hyaluronidase, Desoxycorticosterone and Artisone on Experimental Serum Disease in Rabbits The Effect of Hyaluronidase on Some Physiological and Pathological Processes Am. J. Med. Sci, 1950 219 346-347 Anat. Rec. Ann. N.Y. Acad. Sci. Proc. Soc. Exp. Biol. Med. Proc. Soc. Exp. Biol. Med. Bull. Schweiz. Akad. Med. Wiss. 1950 106 525-536 1950 52 1141-1155 1950 74 796-798 1950 75 337 1951 8 67-73 * "P" denotes paper -5- ------- *P# AUTHORS TITLE JOURNAL YEAR VOL. PAGE 38. Arthur J. Butt Ernst A. Hauser Joseph Seifter 39. Arthur J. Butt Ernst A. Hauser Joseph Seifter 40. Arthur J. Butt Ernst A. Hauser Joseph Seifter Joseph Q. Perry 41. Joseph Seifter Jerome M. Classman Albert J. Begany Edward M. Gore 42. Wm. E. Ehrich Carolyn W. Forman Joseph Seifter 43. Joseph Seifter David H. Baeder Wm. J. Beckfield Gyani P. Shama Wm. E. Ehrich Effect of Hyaluronidase on Urine and Its Possible Significance in Renal lithiasis Medical Management of Renal Lithiasis: Increasing the Protective Urinary Colloids with Hyaluronidase Renal Lithiasis: A New Concept Concerning Etiology, Prevention and Treatment The Effect of Aluminum Hydroxide Gel (Amphojel) and Hydrated Alumina Powder on the Intensity and Duration of Action of Anticholinergic Drugs Diffuse Glomerular Nephritis and lipid Nephrosis Effect of Hyaluronidase on Experimental Hypercholesterolemia in Rabbits and Rats and Atheromatosis in Rabbits J. Am. Med. Assoc. 1952 150 1096-1098 Calif. Med. South. Med. J. J. Pharmacol, Exp. Ther. Arch, pathol. Proc. Soc. Exp. Biol. Med. 1952 75 123-129 1952 45 381-388 1952 1953 105 96-100 54 463-503 1953 83 468-473 44. Jerome M. Classman Effects of Hyaluronidase on Inflammation Albert Blumenthal Wm. J. Beckfield Joseph Seifter Proc. Soc. Exp. Biol. Med. 1953 82 323-328 * "p" denotes paper -6- ------- *Pf AUTHORS TITLE JOURNAL TEAR VOX.. PAGE 45. Joseph Seifter Wm. E. Ehrich David H. Baeder Arthur J. Butt Ernst A. Hauser Evidence for the Direct Effect of Steroids on the Ground Substance Ann. N.Y. Acad. Sci. 1953 56 693-697 46. Arthur J. Butt Joseph Seifter Ernst A. Hauser 47. Joseph Seifter David H. Baeder 48. Joseph Seifter David H. Baeder Wm. J. Beckfield Effects of Hyaluronidase, Cortisone, Stress & Bacteria on Protective Urinary Colloids & Their Relationship to Renal Calculous Disease Partially Depolymerized Hyaluronic Acid (PDHA) as a Spreading Agent The Effect of Streptococcal Hyaluronic Acid (SHA) in Mice, Rats, Rabbits, and Dogs J. Fla. Med. Assoc. Proc. Soc. Exp. Biol. Med. Proc. Soc. Exp. Biol. Med. 1953 40 173-177 1954 85 160-162 1954 85 444-446 49. David H. Baeder Wm. J. Beckfield Joseph Seifter Effect of Aluminum Hydroxide Gels on Experimental Hypercholesterolemia and Atheromatosis in Chicks Proc. Soc. Exp. Biol. Med. 1954 86 326-329 50. Joseph Seifter Jerome M. Classman Albert J. Begany Wm. E. Ehrich Wm. J. Bechfield The Pharmacology of N,N-Dibenzylethylenediamine Antibiot. (DEED) and DEED Dipenicillin G (Bicillin) Chemother. 1954 4 633 51. Joseph Seifter David H. Baeder 52. Jerome M. Classman Joseph Seifter Lipemia Clearing by Hyaluronidase, Hyaluronate and Deoxycorticosterone and Its Inhibition by Cortisone, Stress and Nephrosis The Effect of Mephentemine on Hypodynamic and Arrhythmic Isolated Prog Hearts Proc. Soc. Exp. Biol. Med. J. Pharmacol. Exp. Ther. 1954 86 709 1954 112 364-373 * "P" denotes paper -7- ------- *Pf AUTHORS TITLE JOURNAL YEAR VOL. PAGE 53. Donald K. Eckfeld Liese L. Abe 11 Joseph Seifter 54. David H. Baeder Joseph Seifter 55. S.S. Walkenstein M. Kuna Joseph Seifter Pharmacological Properties of Mephentemine, a Sympathomimetic Amine Technical Factors Influencing Permeability of the Synovial Membrane in Rabbits Fate and Sojourn of C14-Dibenzylethylenediamine (DEED) and C14-DBED Dipenicillin G (Bicillin) Following Oral and Intramuscular Injection J. Am. Pharm. Assoc. Proc. Soc. Exp. Biol. Med. Antibiot. Chemother. 1954 XLIII 705-708 1954 87 276 1954 4 700-706 56. David H. Baeder Joseph Seifter 57. S.S. Walkenstein Nina Chumakow Joseph Seifter 58. Joseph Seifter J.M. Glassmann Albert J. Begany Albert Blumenthal Effect of Adrenalectomy and Hypophysectomy on Permeability of Synovial Membrane in Rabbits Fate and Sojourn of Dibenzylethylenediamine C14-Dipe.nicillin G and C14-Penicillin G Following Oral and Intramuscular Injection The Toxicologic Prop. Dipenicillin V of Penicillin V and Proc. Soc. Exp. Biol. Med. Antibiot. Chemother. Antibiot. Ann. 1954 87 280 1954 IV 1245-1250 1955- 1956 534-540 59. Joseph Seifter David H. Baeder influence of Calcium and Serum Albumin on Clearing of Lipemic Dog Plasma Tn. Vitro 60. David H. Baeder Effect of Hyaluronidase and Partially Jerome M. Glassman Depolymerized Hyaluronate on Threshold Doses George M. Hudyma of Drugs Joseph Seifter 61. Jerome M. Glassman The Effect of Analgesic Agents on Barbiturate Joseph Seifter Responses in Mice Proc. Soc. Exp. Biol. Med. Proc. Soc. Exp. Biol. Med. J. Pharmacol. Exp. Ther. 1955 89 511-514 1955 89 645-647 1955 115 21 * "P" denotes paper —8— ------- 'Pf AUTHORS TITLE JOURNAL YEAR VOL. PAGE 62. S.S. Walkenstein Nina Chumakow Joseph Seifter 63. A. S. Weisberger leif G. Surland Joseph Seifter 64. Joseph Seifter David H. Baeder 65. Joseph Seifter David H. Baeder 66. Harry Rosen Patricia Townsend Joseph Seifter 67. Joseph Seifter David H. Baeder 68. R.A. Huebner J.M. Classman G.M. Hudyma Joseph Seifter 69. Harry Rosen Patricia Townsend Joseph Seifter 70. Joseph Seifter David H. Baeder Detoxication and Excretion of Mephentemine Studies on Analogues of L-Cysteine and L-Cystine: 1. Some Structural Requirements for Inhibiting the Incorporation of Radio- active L-Cystine by leukocytes Occurrence in Plasma of an Extractable Lipid Mobilizer (IM) Persistent Hyperlipemia Following Injection of a Clearing Factor-Inhibitor Effect of Sodium Polyanhydromannuronic Acid Sulfate in Incidence of Ulcers in the Shay Rat Assay of Drugs on Connective Tissue Permeability J. Pharmacol. Exp. Ther. Blood Proc. Soc. Exp. Biol. Med. Circulation Fed. Proc. Ann. N.Y. Acad. The Toxic Dose of Dihydrostreptomycin in Fowl Cornell Vet. Effect of Sodium Polyanhydromannuronic Acid Proc. Soc. Exp. Sulfate on Incidence of Ulcers in the Shay Rat Biol. Med. Relation of Endocrines and Clearing Factor- Proc. Soc. Exp. Inhibitors to Hyperlipemia in Fasted Animals Biol. Med. 1955 115 16-20 1956 XI(1) 1-10 1956 91 42-43 1955 12 491 1956 15 475 1956 64 476 1956 XLVI 219 1956 92 439 1956 93 63-67 * "P" denotes paper -9- ------- *P# AUTHORS TITUB JOURNAL YEAR VOL. PAGE 71 • Harry Rosen Albert Blumenthal P.M. Townsend R. Tislow Joseph Seifter 72. W. Steigner C.J.D. Zarafonetis Gladys M. Miller Joseph Seifter David H. Baeder Oxytocic Activity of Aminoacetamides and Propionamides Preliminary Report on the Effects of a Plasma Lipid Mobilizing Factor in Man J. Pharmacol. Exp. Ther. 1956 Am. J. Med. Sci. 1956 117 488 232 605 73. C.J.D. Zarafonetis Further Observation of the Effects of a J. lab. Clin. Med. 1956 48 961 Gladys M. Miller W.A. Steiger David H. Baeder R. Myerson Joseph Seifter 74. Joseph Seifter David H. Baeder 75. Joseph Seifter David H. Baeder Plasma lipid Mobilizing Factor in Man lipid Mobilizer (IM) from the Posterior Pituitary of Hogs lipid Mobilization by a Crystalline Peptide Isolated from Plasma of Horses Administered Cortisone Proc. Soc. Exp. Biol. Med. Proc. Soc. Exp. Biol. Med. 1957 1957 95 318-332 95 469-471 76. Harry Rosen Albert Blumenthal Mary H. Nead R. Tislow Joseph Seifter Diuretic Effects of Some Mercurate Substituted N-n-propylurea Derivatives Proc. Soc. Exp. Biol. Med. 1957 95 635-636 * "p" denotes paper -10- ------- *Pf AUTHORS TITLE JOURNAL YEAR VOL. PAGE 77. S.S. Walkenstein The Metabolic Fate of a Hexamethylenimine Joyce A. MacMullen Analgesic C. Knebel Joseph Seifter 78. C.J.D. Zarafonetis Metabolic Studies in patients Receiving Gladys M. Miller Joseph Seifter David H. Baeder R.M. Myerson W.A. Steiger 79. M.J. Hosko E.M. Gore R. Tislow Joseph Seifter 80. Joseph Seifter David H. Baeder lipid Mobilizer Hormone Taming Effect of Promazine in the Rhesus Monkey Role of liver on Consequences of lipid Mobilization J. Am. Pharm. Assn. Am. J. Med. Sci, 1957 XLVII 20-25 J. Pharmacol. Exp. Ther. Proc. Soc. Exp, Biol. Med. 1957 234 493-504 1957 1957 119 153-4 95 747-750 81. S.S. Walkenstein C.M. Knebel J.A. MacMullen Joseph Seifter 82. C.J.D. Zarafonetis Gladys M. Miller Joseph Seifter David H. Baeder The Excretion and Distribution of Meprobamate and its Metabolites Effect of Prefeeding on the Acute Responses to lipid Mobilizer Hormone in Man J. Pharmacol. 1958 Exp. Ther. Am. J. Med. Sci. 1958 123 254-258 235 410-419 83. S.S. Walkenstein Joseph Seifter -Fate, Distribution and Excretion S35 Promazine J. Pharmacol. Exp. Ther. 1959 125 283-286 * "P" denotes paper -11- ------- *P# AUTHORS TITLE JOURNAL YEAR VOL. PAGE 84. C.J.D. Zarafonetis David H. Baeder Joseph Seifter J. Kalas Lipid Mobilization as a Consequence of Surgical Stress Am. J. Med. Sci. 1959 237 418-433 85. Joseph Seifter David H. Baeder C.J.D. Zarafonetis J. Kalas Hormonal Control of Permeability and Mobilization of Fat Depots Ann. N.Y. Acad. Sci. 1959 72 1031-1044 86. C.J.D. Zarafonetis Joseph Seifter David H. Baeder J. Kalas W.Y.M. Chang 87. C.J.D. Zarafonetis Joseph Seifter David H. Baeder J. Kalas Inhibition of lipid Mobilization of Surgical Stress by Partially Depolymerized Hyaluronic- Acid Current Clinical Status of lipid Mobilizer Hormone Am. J. Med. Sci. AMA Arch. Int. Med. 1959 237 771-780 1959 104 974-981 88. E.M. Gore F.V. Hadley R. Hslow Joseph Seifter 89. I. Geller Joseph Seifter Neurolathyrism in the Rhesus Monkey Induced by )3,/31 Bninodipropionitrile The Effects of Meprobamate, Barbiturates, Amphetamine and Promazine on Experimentally Induced Conflict in the Rat Psychiatr. Res. Rep. 1959 Psychopharmacologia 1960 II 115-118 1 482-492 90. I. Geller A.O. Demarco Joseph Seifter Delayed Effect of Nicotine on Timing Behavior in the Rat Science 1960 131 735-737 * "P" denotes paper -12- ------- *P# AUTHORS TIT IE JOURNAL YEAR VOL. PAGE 91 . L. Stein Joseph Seifter 92. I. Geller J.T. Kulak, Jr. Joseph Seifter 93. G.E. Farrar, Jr. Joseph Seifter 94. I. Geller Joseph Seifter 95. G.H. Warren Joseph Seifter J.M. Classman 96. Joseph Seifter J.M. Classman G.M. Hudyma 97. L. Stein Joseph Seifter 98. J. Glassman A. Dervinis W. Beckfield Joseph Seifter 99. I. Geller E. Bachman Joseph Seifter Possible Mode of Antidepressive Action of Bnipramine Science 1961 134 286-287 The Effects of Chlordiazepoxide and psychopharmacologia 1962 Chlorpromazine on a Punishment Discrimination Gastrointestinal Dysfunction Modified by a Topical Anesthetic The Effects of Monourethans, Diurethans and Barbiturates on a Punishment Discrimination Inhibition of Hyaluronidase by Urinary Kallikrein Oxethazaine and Related Congeners: A Series of Highly Potent Local Anesthetics Muscarinic Synapses in the Hypothalamus Acute and Chronic Toxicity of Oxethazaine Effects of Reserpine and Morphine on Behavior Suppressed by Punishment Pa. Med. J. Pharmacol. Exp. Ther. Nature (London) Proc. Soc. Exp. Biol. Med. Am. J. Physiol, Toxicol. Appl. Pharmacol. Life Sci. 1963 100. Joseph Seifter Tribute to a Charter Member: Torald Sollmann Pharmacologist 1963 1965 3 374-385 1962 65 1369-1373 1962 136 284-288 1962 194 770-771 1962 109 664-668 1962 202 751-756 5 184 4 226-231 7 68-69 * "P" denotes paper -13- ------- *Pf AUTHORS TITLE JOURNAL YEAR VOL. PAGE 101. Joseph Seifter Re: Torald Sollmann West. Res. Univ. Sch. of Med. Alumni Bull. 1965 29(1) 12 102. S. Kramer Joseph Seifter The Effects of Gaba and Biogenic Amines on Behavior and Brain Electrical Activity in Chicks Life Sci. 1966 5 527-534 103. S. Kobrin Joseph Seifter 104. S. Kramer Joseph Seifter P. Sherman 105. F.J. Rauzzino Joseph Seifter 106. B. Bhagat S.Z. Kramer Joseph Seifter 107. S. Kramer Joseph Seifter B. Bhagat 108. Joseph Seifter G. Guideri Eli Seifter 109. J.P. Hanig E.L. Aiello Joseph Seifter co-Amino Acids and Various Biogenic Amines as Antagonists to Pentylenetetrazol Effects of Gamma-Aminobutyric Acid and Sodium L-Glutamate on the Visual System and EEC of Chicks Potentiation and Antagonism of Biogenic Amines The Effects of Nicotine & Other Drugs on the Release of Injected H-Norepinephrine & on Endogenous Norepinephrine Levels in the Rat Brain Regional Distribution of Tritiated Acetylcholine in Rat Brain Effect of Tetraphenylboron (Ph4/3), A Negative Quaternary, on Muscle Contraction and Enzyme Action: A New View of Activation and Blockade of Cholinergic Receptors The Effects of Stress and Intravenous 0.9% NaCl Injection on Concentrations of Whole Brain 5-Hydroxytryptamine in the Neonate Chick J. Pharmacol. Exp. Ther. Int. J. Neuropharmaco1. J. Pharmacol. Exp. Tner. Eur. J. Pharmacol. 1966 154 646 Na ture (London) Eur. J. Pharmacol. J. Pharmac. 1967 1967 1968 6 463-472 1967 157 143-148 2 234-235 1967 217 184-185 3 263 1970 22 317-318 * "P" denotes paper -14- ------- *Pf AUTHORS TITLE JOURNAL YEAR VOL. PAGE 110. J.P. Hanig E. Aiello Joseph Seifter 111. Joseph Seifter J.P. Hanig Neil Edison Eli Seifter Permeability of the Blood-Brain Barrier to Parenteral 5-Hydroxytryptamine in the Neonate Chick Effect of vasoactive Drugs on the Residual Content of Blood in the Brain of Chicks Eur. J. Pharraacol. 1970 Eur. J. Parmacol. 1970 12 180-182 11 29-32 112. J.P. Hanig Joseph Seifter 113. Eli Seifter G. Rettura Joseph Seifter A. Nagler S.M. levenson 114. K. Blum Eli Seifter Joseph Seifter 115. G. Guideri Eli Seifter Joseph Seifter 116. Joseph Seifter Eli Seifter G. Guideri 117. J.P. Hanig Joseph Seifter L-DOPA Administration to Neonate Chicks: Effects on Behavior and levels of Brain Biogenic Amines Gall Bladder Distension in Choline-deficient Chicks 1,2 The Parmacology of d- and 1-Garnite and d- and 1-Acetylcarnitine: Comparison with Choline and Acetycholine Effects of a Negative Quaternary Ibn- Sodium Tetraphenylboron on the Rat Phrenic Nerve-Diaphragm Preparation Catecholamine Reactions and Complex Formations with MgHPO4 and MgATP Experientia J. Nutr. J. Pharmacol. Exp. Ther. Eur. J. Pharmacol. Am. J. Med. Sci. The Effects of Parenteral Administration of CA, Arch. Int. Serotonin & Histamine on Behavior & Levels of Pharmacodyn These Amines in the Brain of the Neonate Chick 1971 1971 1971 1972 27 168-169 1233-1240 178 331-338 17 253-258 1972 263 261-266 1973 202 38-47 * "p" denotes paper -15- ------- *P# AUTHORS TITLE JOURNAL YEAR VOL. PAGE 118. Eli Seifter G. Rettura M. Zisblatt S.M. levenson N. levine A. Davidson Joseph Seifter 119. G. Rettura Joseph Seifter M. Zisblatt S.M. levenson N. levine Eli Seifter Enhancement of Tumor Development in Physically-Stressed Mice Inoculated with an Oncogenic Virus Experientia 1973 29 1379-1382 Metyrapone-Inhibited Oncogenesis in Mice Inoculated with a Murine Sarcoma Virus J. Nat. Cancer Ihst. 1973 51 1983-1985 120. D.F. Ventura Joseph Seifter 121. G. Guideri Joseph Seifter 122. G. Guideri Eli Seifter Joseph Seifter 123. Eli Seifter Giuseppe Rettura A. A. Demetriou Stanley levenson Syed Rahman Joseph Seifter 124. Joseph Seifter Effect of N-Dipropyl Acetic Acid and 1,2-Di-2/4-Dichlorophenyl Ethanolamine on Seizures and Fatality by Tetraphenylboron Effects of Tetraphenylboron on Frog Skeletal and Cardiac Muscle Effects of Tetraphenylboron (TPB) on the Autonomic Nervous System Inhibition of Murine Sarcoma Development by Deoxycorticosterone Acetate Pharmacologi s t Arch. Int. Pharmacodyn Ther, Arch. Int. Pharmacodyn Ther. (Belgium) J. Nat. Cancer Ihst. 1974 16 227 1974 212 302-303 1974 208 224-232 1974 53 1809 Editorial. Ascorbic Acid and the Common Cold J. Clin. Pharmacol. 1975 15 569 * "p" denotes paper -16- ------- *Pf AUTHORS JOURNAL YEAR VOL. PAGE 125. Eli Seifter Giuseppe Rettura Stanley M. levenson Mark Appleman Joseph Seifter 126. Joseph Seifter Aspirin Inhibits a Murine Viral Infection 127. R.D. Short J.M. Minor Joseph Seifter C.C. Lee Hydrocarbon Exposure and proliferative Glomerulonephritis the Effects of various Treatments on the Toxicity of Inhaled vinylidene Chloride life Sci. lancet Environ. Health Perspect. 1975 16 629-636 1977 1151 1977 21 125-129 128. R.D. Short J.M. Winston J.L. Minor C.B. Hong Joseph Seifter C.C. lee 129. R.D. Short J. L. Minor J.M. Winston Joseph Seifter C.C. lee 130. F.J. DiCarlo Joseph Seifter V.J. DeCarlo The Toxicity of Vinylidene Chloride and Rats and Its Alteration by Various Treatments Inhalation of Ethylene Dibromide During Gestation by Rats and Mice Assessment of the Hazards of Polybrominated Biphenyls J. Toxicol. Environ. Health 1977 3 913-921 Toxicol. Appl. Pharmacol. Environ. Health Perspect. 1978 46(1) 173-182 1978 23 351-365 * "" P" denotes paper -17- ------- *P# AUTHORS TIT IE JOURNAL YEAR VOL. PAGE 131. E.M. Cause D.H. Ross M.G. Hamilton B.Z. Leal Joseph Seifter I. Geller Correlation of Systemic and Biochemical Effects of PBB with Behavioral Effects Neurobehav. Toxicol. 1979 1 269-274 132. I. Geller R.J. Hartmann C. Garcia Joseph Seifter 133. W.H. Beinfield Joseph Seifter 134. W.H. Beinfield Joseph Seifter 135. C.F. Allen-Rowlands V.D. Castracane M.G. Hamilton Joseph Seifter Effects of Polybrominated Biphenyl on a Discrimination Task in Rats Spontaneous Mechanical Activities of Dog Trachealis Muscle In Vivo Contraction of Dog Trachealis Muscle In Vivo: Role of Adrenergic Receptors Effect of Polybrominated Biphenyls (PBB) on the Pituitary-Thyroid Axis of the Rat (41099) Neurobehav. Toxicol. J. Appl. Physiol. J. Appl. Physiol. Proc. Soc. Exp. Biol. Med. 1979 1 263-267 1980 48 320-328 1980 48 329-336 1981 166(4) 506-514 p" denotes paper -18- ------- COLLECTION OF MONOGRAPHS AND EXCERPTS ------- MONOGRAPHS AND EXCERPTS *M# AUTHORS TITLE PUBLISHER YEAR Page 1. Joseph Seifter General Pharmacology and Toxicology of Quinones and Hydroquinones* In: Biological Antioxidants. J. Macy Jr. Foundation 1948 50-57 2. Joseph Seifter Pharmacology of the Ground Substance. In: Immunity and Hypersensitivity Relationship to Disease in Man. Columbus OH: M s R Laboratories 1953 71-79 3. W.E. Ehrich Joseph Seifter 4. Joseph Seifter David H. Baeder Chapter 4: The Effect of Corticosteroids upon Columbia U. Press Lymphoid Tissue. In: The Effect of ACTH and Cortisone upon Infection and Resistance. Chapter 16: Urine. In: Lithiasis. Effect of Hyaluronidase on Human Etiologic Factors in Renal Charles C. Thomas 1953 1956 25-45 304-319 5. C.J.D. Zarafonetis Joseph Seifter David H. Baeder J. Kalas Chapter 20: Effect of Adrenals, Pituitary, Liver and Mucopolysaccharides on Blood Lipids. In: Hormones and Atherosclerosis. Academic Press 1958 265-281 6. C.J.D. Zarafonetis Joseph Seifter David H. Baeder J. Kalas Chapter 28: Lipid Mobilizing Factor: Possible Role in Coagulation and Myocardial Infarction. In: The Etiology of Myocardial Infarction. Little Brown & Co. 1963 441-457 7. Joseph Seifter M. Urivetsky Eli Seifter Lipid Mobilizing Peptide in Hog Pituitary & Human Urine. In: Pharmacology of Hormonal Polypeptides and Proteins. Plenum Press 1968 440-448 * "M" denotes monograph or excerpt -20- ------- COLLECTION OF ABSTRACTS ------- ABSTRACTS *Ai AUTHORS TITLE JOURNAL YEAR VOL. PAGE 1. Joseph Selfter 2. J. Begany Joseph Seifter 3. Joseph Seifter A.J. Begany 4. Joseph Seifter William E. Ehrich Albert J. Begany George M. Hudyma 5. Joseph Seifter David H. Baeder Albert J. Begany 6. Joseph Seifter John J. Christian William E. Ehrich 7. William E. Ehrich Joseph Seifter George M. Hudyma 8. Alphonse Dervinis Joseph Seifter William E. Ehrich Prolonged Administration of Goitrogenic Compounds to Dogs Fed. Proc. Studies on a Heparin-like Compound, Algarin Fed. Proc. Studies on the Action of A Synthetic Heparinoid Epinephrine and Dibenamine in the Alarm Reaction Method of Screening Steroids on Synovial Membrane for Possible Antiarthritic Action Am J. Med. Sci. Fed. Proc. Fed. Proc. Effects of Cortisone and Other Steroids on the Fed. Proc. Hibernating Gland of the Pregnant White Rat Effect of the Alarm Reaction upon Lymphocytes and Plasma Cells Effect of Cortisone and 2,1-Acetoxy- Pregnenolone on Experimental Arthritis Fed. Proc. Fed. Proc. 1947 1948 1949 1950 6 370 7 206 1948 216 234-235 8 331-332 9 314 1951 10 334 1951 10 354 1952 11 338 * "A" denotes abstract -22- ------- *A| ADTHORS TITLE JOURNAL YEAR VOL. PAGE 9. O.K. Eckfeld L. Abell Joseph Seifter 10. Albert J. Begany Joseph Seifter Harvey H. Pless Richard DeV. Huber William F. Bruce Pharmacological Properties of Mephentermine, a Sympathomimetic Amine Tranquilizing Effect of Phenothiazines in Cats and Rabbits ACS Abstract Fed. Proc. 1955 49 3412f 1956 15 399-400 11. Joseph Seifter David H. Baeder 12. Jerome M. Glassman Robert W. Heaton Joseph Seifter 13. David H. Baeder Bernard Shore John W. Gofman Joseph Seifter 14. Donald K. Eckfeld Richard Tislow Joseph Seifter 15. Joseph Seifter A. Begany J. Glassman M. Hosko H. Pless E. Gore R. Tislow The Relation of Clearing Factor Inhibitors to Hyperlipemia Myocardial Activity of Some Sympathomimetic Amines Effect of Mucopolysaccharides on the Lipemia Clearing Reaction Hypnotic Effect of Polyhydric Alcoholchloral Hemiacetals Correlation of Some Pharmacological Actions of Phenothiazines in Animals with Ataractic Action in Humans Fed. Proc. Fed. Proc. Fed. Proc. Fed. Proc. Am. J. Med. Sci. 1956 15 481 1956 15 428 1956 15 396 1956 15 419 1957 233 718-719 * "A" denotes abstract -23- ------- b S UNITED STATES ENVIRONMENTAL PROTECTION AGENCY $ WASHINGTON, D.C. 20460 MAY 6 1983 ^ OFFICE OF A™' _, - * PESTICIDES AND TOXIC SUBSTANCES MEMORANDUM TO: Colleagues and Friends of the Late Dr. Seifter SUBJECT: Bibliography I am pleased to send you the chronologic bibliography Scientific Publication and Patents: Joseph Seifter, M.D. It was compiled in recognition of Dr. Seifter 's contributions to the science of toxicology, his work in the Office of Toxic Substances, U.S. Environmental Protection Agency, and in tribute to the memories many of us hold of him personally. Don R. Clay Acting Assistant Administrator for Pesticides and Toxic Substances Attachment ------- *Ai AUTHORS TITLE JOURNAL YEAR VOL. PAGE 16. Joseph Selfter J.M. Glassman F. Rauzzino 17. W.J. Beckfield G. Keller E.M. Gore F.V. Hadley R. Tislow Joseph Selfter 18. J. Glassman G. Hudyma Joseph Selfter 19. Jerome M. Glassman Alphonse Dervinis Joseph Selfter 20. Joseph Selfter David H. Baeder 21. W. Beckfield M. Hirata Joseph Seifter W.E. Enrich Pharmacological Properties of Promazine Pathological Changes Induced by/3,/31- Iminodipropionitrile in the Rehesus Monkey Phenothiazines Antihistaminic Properties and Responses to Analeptic Agents Effects of Phenothiazines, Meprobamate and Pentobarbital on Pulmonary Edema in Mice J. Pharmacol. Exp. Ther. Fed. Proc. J. Pharmacol. Exp. Ther. Fed. Proc. Antilipemic Action of Partially Depolymerized Fed. Proc. Hyaliironic Acid Observations on the Fate of Lymphocyte Fed. Proc. 1957 119 183 1958 17 427 1958 122 25A 1959 1959 1960 395 443 19 241 22. J. Glassman A. Begany H. Pless G. Hudyma Joseph Seifter The Pharmacology of Some Phenoselenazines Fed. Proc. 1960 19 182 * "A" denotes abstract -24- ------- *Ai AUTHORS TITLE JOURNAL YEAR VOL. PAGE 23. J. Classman P. Rauzzino A. Dervinis Joseph Seifter 24. Robert Wiser Cornelius Knebel Joseph Seifter 25. Alphonse Dervinis Jerome M. Classman Robert O. Stewart Cathryn Gudmunsen Joseph Seifter 26. Stanley Z. Kramer Joseph Seifter Felix Rauzzino Effectiveness of Certain Agents Against Pulmonary Edema in Mice The Determination of Promazine in Biological Materials A Pharmacological Comparison of Several Dicarbamates Derived from 2-Substituted 1, 3-Propanediols The Effect of Some Indoles in Chicks Pharmacologist 1960 67 Pharmacologist Pharmacologist Pharmacologist 1960 1962 1963 83 183 246 27. Stanley Z. Kramer Sidney Kobrin Joseph Seifter 28. Stanley Z. Kramer Joseph Seifter 29. S.Z. Kramer Eli Seifter Joseph Seifter 30. J. Hanig E. Aiello Joseph Seifter 31. J.P. Hanig Joseph Seifter Epinephrine, Serotonin and Gamma-Aminobutyric Pharmacologist Acid as Pentlenetetrazol Antagonists in Chickens Electrocortical and Behaviorial Effects of Centrally Active Drugs in Chicks Bed. Proc. Catatonic Behavior and Brain Electrical Fed. Proc. Activity as Influenced by Some Catecholamines and Their Metabolites Brain Distribution of Serotonin (HT) Following Fed. Proc. Parenteral Injection in Chickens One to Ninety Days Old Amines in Brain of Neonate Chicks After Paren- Fed. Proc. teral Injection of Biogenic and Other Amines 1963 1964 1965 1966 1968 23 246 148 24 390 25 452 27 651 * "A" denotes abstract -25- ------- *A# AUTHORS TITLE JOURNAL YEAR VOL. PAGE 32. J. Hanig Joseph Seifter 33. Joseph Seifter Eli Seifter Effect of Drugs on Residual Blood in Brain Fed. Proc. Occurrence of a Lipid Mobilizer in Human Urine ACS Abstract April 1967 26 324 April 153/4 1967 M29 34. K. Blum Eli Seifter Joseph Seifter 35. G. Guideri Eli Seifter Joseph Seifter 36. Joseph Seifter G. Guideri Eli Seifter Pharmacology of Garnitines and Acetylcarnitines. Comparison with Choline and Acetylcholine Pharmacologist Pharmacological Actions of Na Tetraphenylboron Pharmacologist Activation of Muscle Receptors by Electron Donation Pharmacologist June 1968 10 177 June 10 177 1968 June 10 177 1968 37. Eli Seifter Joseph Seifter G. Guideri Effect of Tetraphenylboron on Oxidation of Malate and Glutamate by Mitochondria Pharmacologist June 10 177 1968 38. K. Kasses W.H. Beinfield Joseph Seifter 39. F. Rauzzino W.H. Beinfield Joseph Seifter 40. G. Guideri Eli Seifter Joseph Seifter Alpha Receptors in Isolated Guinea Pig Tracheal Chain Pharmacologist Response of Dogs to Bradykinin Injected into Pharmacologist a Coronary Artery Cholinergic Actions of Na Tetraphenylboron Fed. Proc. June 10 206 1968 June 10 192 1968 1969 28 419 * "A" denotes abstract -26- ------- *At AUTHORS TITLE JOORNAL YEAR VOL. PAGE 41. E. Freeman Joseph Seifter 42. Joseph Seifter G. Guideri Eli Seifter Effect of Quaternary Ions on Muscles; In Vivo Pharmacologist Antagonism of Depolarizing Blockers by Atropine in Chicks Catecholamine Reactions and Complex Formations Fed. Proc. with MgHPO4 and MgATP 1969 11 294 April 29 545 1970 43. Joseph Seifter E. Friedman S. Gershon D.F. Ventura Eli Seifter 44. Eli Seifter G. Rettura Joseph Seifter H. Davidson S.M. Levenson Effect of 2-Arylalanines, 2-Arylserines, Tetraphenylboron and 1 , 2-di(2,4-Di- chlorophenyD-Ethanolamine on Levels of Serotonin (5HT), Norepinephrine (NE) and Dopamine (DM) in Whole Brain of Mice Thymotropic Action of Vitamin A Fed. Proc. 1973 32 816 Fed. Proc. 1973 32 947 * "A" denotes abstract -27- ------- COLLECTION OF PATENTS ------- PATENTS *PT§ INVENTORS PATENT U.S. NO. DATE 1. 2. 3. 4. 5. 6. 7. 8. 9. W.F. Bruce Joseph Seifter W.F. Bruce G. Mueller Joseph Seifter J.L. Szabo W.F. Bruce Joseph Seifter W.F. Bruce Joseph Seifter W.F. Bruce Joseph Seifter J.W. Opie Joseph Seifter W.F. Bruce G. Mueller W.F. Bruce Joseph Seifter W.F. Bruce Joseph Seifter W.F. Bruce Joseph Seifter Substituted Glycinamides 2,449,638 Barbituric Acid Derivatives and Process for 2,494,084 Preparing Them Substituted Glycinamides 2,499,352 Substituted Glycinamide 2,516,674 Substituted Glycinamides 2,523,275 5-Alpha-Cyclopropylethyl Substituted 2,538,322 Barbituric Acids and Process for Preparing Same Substituted Glycinamides 2,548,863 Substituted Glycinamides 2,568,141 Aryl-Glycinedialkylamides 2,568,142 09/21/48 01/10/50 03/07/50 07/25/50 09/26/50 01/16/51 04/17/51 09/18/51 09/18/51 * "PT" denotes patent -29- ------- *PT§ INVENTORS PATENT O.S. NO. DATE 10. Liese L. Abell W.F. Bruce Joseph Seifter 11. W.F. Bruce Joseph Seifter 12. W.F. Bruce Joseph Seifter 13. ,W.F. Bruce Joseph Seifter 14. W.F. Bruce Joseph Seifter 15. Joseph Seifter 16. W.F. Bruce Joseph Seifter 17. Joseph Seifter W.F. Bruce 18. W.F. Bruce Joseph Seifter 19. H.E. Alburn Joseph Seifter 20. L.L. Abell W.F. Bruce Joseph Seifter 21. W.F. Bruce Joseph Seifter Tertiary Butyl Amines and Their Preparation 2,590,079 Substituted Glycinamides Substituted Glycinamides Acylated Glycinamides Substituted Glycinamides Analgesic Composition Substituted Glycinamides Substituted Glycinamides Substituted Glycinamides Sulfated Pectic Acid Blood Anticoagulant 2,654,754 2,665,309 2,676,188 2,678,948 2,687,366 2,692,265 2,700,680 2,719,862 2,729,633 Tertiary Butylamines and Their Preparation German 939506 Substituted Glycinamides German 942149 03/25/52 10/06/53 01/05/54 04/20/54 05/18/54 08/24/54 10/19/54 01/25/55 10/04/55 01/03/56 02/23/56 04/26/56 * "PT" denotes patent -30- ------- *PTi 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. INVENTORS W.F. Bruce Joseph Seifter W.F. Bruce Joseph Seifter Joseph Seifter R.S. Hanslick M.E. Freed Joseph Seifter A.L. Monaco F.J. Hoover Joseph Seifter David H. Baeder Joseph Seifter W.F. Bruce W.F. Bruce R.S. Hanslick Joseph Seifter M.E. Freed Joseph Seifter David H. Baeder Joseph Seifter B. Hanslick R.S. Hanslick M.E. Freed Joseph Seifter Berwyn David H. Baeder PATENT O.S. NO. Substituted Glycinamides 2,768,166 Substituted Glycinamides 2,778,834 Fatty Acid Amides and Derivatives Thereof 2,780,646 Anti-Exgitatory Compositions 2,799,619 Depolymerized Hyaluronic Acid 2,850,428 Substituted Glycinamides 2,856,427 Fatty Acid Amides and Derivatives Thereof British 802995 Depolymerized Hyaluronic Acid German 1047380 Nicotinic Acid Ester of Certain 2,945,041 Hydroxy-Alkyleneimino-Diacetamides Lipid Mobilizing Composition 3,002,888 DATE 10/23/56 01/22/57 02/05/57 07/16/57 09/02/58 10/14/58 10/15/58 1 2/24/58 07/12/60 10/03/61 "r~irPTM~denotes patent -31- ------- *PTf INVENTORS PATENT U.S. NO. DATE 32. Joseph Seifter C.H. Gudmundsen 33. W.F. Bruce R.S. Hanslick Joseph Seifter Haloalkyl-1, 3-Propanediol Dicarbamates 3,133,959 Process for Making 2-Secondary and Tertiary 3,252,976 Amino-1-Phenylethane Thiols 05/19/64 05/24/66 * "p-p" denotes patent -32- ------- JOURNAL ABBREVIATION INDEX Abbreviation journal Title ACS Abstract AMA Arch. Bit. Med. Am. J. Med. Sci. Am. J. Physiol. Anat. Rec. Ann. N.Y. Acad. Sci. Antibiot. Annu. Antibiot. Chemother. Arch. Biochem. Arch. Ht. pharmacodyn. Arch. Int. Pharmacodyn. Ther. Arch. Pathol. Blood Bull. N.Y. Acad. Med. Bull. Schweiz. Akad. Med. Wiss. American Chemical Society Abstract American Medical Association Archives of Internal Medicine American Journal of the Medical Sciences American Journal of Physiology Anatomical Record Annals of the New York Academy of Science Antibiotics Annual Antibiotics and Chemotherapy Archives of Biochemistry Archives Jhternationales de Pharmacodynamie Archives Internationales de Pharmacodynamies et de Therapie Archives of Pathology Blood Bulletin of the New York Academy of Medicine Bulletin der Schweizerischen' Akademie der Medizinischen Wissenschaftenn -33- ------- Abbreviation Journal Title Calif. Med. Circulation Cornell Vet. Environ. Health Perspect. Eur. J. Pharmacol. Experientia Fed. Proc. Int. J. Neuropharmacol. J. Allergy J. Am. Chem. Soc. J. Am. Med. Assoc. J. Am. Pharm. Assoc. J. Appl. Physiol. J. Clin. Pharmacol. J. Exp. Med. J. Fla. Med. Assoc. J. Immunol. J. Bid. Hyg. Toxicol. J. lab. Clin. Med. California Medicine Circulation Cornell Veternarian Environmental Health Perspectives European Journal of Pharmacology Experientia Federation Proceedings, Federation of American Societies for Experimental Biology International Journal of Neuropharmacology Journal of Allergy Journal of the American Chemical Society Journal of the American Medical Association Journal of the American Pharmaceutical Association Journal of Applied Physiology Journal of Clinical Pharmacology Journal of Experimental Medicine journal of the Florida Medical Association Journal of Immunology Journal of Industrial Hygiene and Toxicology Journal of laboratory and Clinical Medicine -34- ------- Abbreviation Journal Title J. Pharm. Pharmacol. J. Pharmacol. Exp. Ther. J. Nat. Cancer Inst. J. Nutr. J. Toxicol. Environ. Health J. Urol. lancet life Sci. Nature (London) Neurobehav. Toxicol. Pa. Med. Pharmacologist Proc. Soc. Exp. Biol. Med. Psychiatr. Res. Rep. Psychopharmacologia Reserve Pharmacon South. Med. J. Toxicol. Appl. Pharmacol. West. Res. Univ. Sch. Med. Alumni Bull. Journal of Pharmacy and Pharmacology Journal of Pharmacology and Experimental Therapeutics Journal of the National Cancer Institute journal of Nutrition Journal of Toxicology and Environmental Health Journal of Urology Lancet life Sciences Nature Neurobehavioral Toxicology Pennsylvania Medicine Pharmacologist Proceedings of the Society for Experimental Biology and Medicine Psychiatric Research Reports Psychopharmacologia Reserve Pharmacon Southern Medical Journal Toxicology and Applied Pharmacology Western Reserve University School of Medicine Alumni Bulletin -35- ------- SUBJECT INDEX ACTH, 20: M3 2,1-Acetoxy-pregnenolone, 5:P31; 22:A8 Acetycholine, 14:P107; 15:P114; 26:A34 ' Acetylcarnitines, 15:P114; 26:A34 Adrenalectomy, 8:P56 Adrenergic Receptors, 18:P134 Alarm Reaction, 3:P19; 22:A7 Algarin, 22: A2 5-Alpha-Cyclopropylethyl Substituted Barbituric Acids, 29:PT6 Alpha Receptors, 26:A38 Aluminum Hydroxide Gel, 6:P41; 7:P49 Amines, 3:P18; 25:A31 Amino Acids, 14:P103 Amino Compounds, 2:P7 Amino-1-Phenylethane Thiols, 32:PT33 Aminoacetamides, 10:P71 Amphetamine, 3:P14; 12:P89 Amphojel, 6:P41 Analeptic Agent, 24:A18 Analgesic Agents, 8:P61; 30:PT15 Anesthetic, 13:P93 Anti-Exgitatory Compositions, 31:PT25 Antiarthritic Action, 5:P31; 22:A5 Anticholinergic Drugs, 6:P41 Anticoagulant, 30:PT19 Antithyroid Compounds, 4:P27 Arsines, 2:P3 Arthritis, 23: A8 Artisone, 5:P36 2-Arylalanines, 27:A43 Aryl-Glycinedialkylamides, 29:PT9 2-Arylserines, 27:A43 Ascorbic Acid, 16:P124 Aspirin, 17:P125 Atheromatosis, 6:P43; 7:P49 Atropine, 27:A41 B Barbiturate, 2:P6; 8:P61; 12:P89; 13:P94 Barbituric Acid Derivatives, 29:PT2 Bicillin, 7:P50; 8:P55 Biogenic Amines, 14:P102, 14:P103; 14:P105 15:P112 Bismuth Subsalicylate, 3:P12 Bismuth, 2:P1; 3:P10; 3:P12 Blood Lipids, 19:M5 Blood-Brain Barrier, 15:P110 Bone, 5:P33 Bradykinin, 26:A39 Brain, 15:P110; 27:A43 Butylamines, 30:PT20 C14 Pencillin G, 8:P57 Calcium, 8:P59 Carbon Tetrachloride, 3:P16 Carnite, 15:P114 Garni tines, 26:A34 Catecholamine 15:P116; 15:P117; 27:A42 Centrally Active Drugs, 25:A28 Cerebrum, 3:P18 Chlordiazepoxide, 13:P92 Chlorpromazine, 13:P92 Choline, 15:P113; 15:P114; 26:A34 Cholinergic Receptors, 14:P108 Clearing Factor-Inhibitor, 9:P65; 9:P70; 23:A11 Complement, 2:P7; 2:P8 Corticosteroids, 20: M3 Cortisone, 5:P36; 7:P46; 7:P51; 10:P75; 20: M3 1-Cysteine, 9:P63 1-Cystine, 9:P63 Reference Notes: Collection of Papers (P), Monographs and Excerpts (M), Abstracts (A), and Patents (PT) -36- ------- DBED (Dibenzylethylendiamine), 7:P50; 8:P57 DBED (Dibenzylethylendiamine) C14, 8:P55 DBED Dipencillin G, 7:P50; 8:P57 De-Polymerized Hyaluronic Acid, 8:P60; 24:A20; 31:PT26; 31:PT29 Deoxycorticosterone, 5:P36; 7:P51; 16:P123 Dibenamine, 22:A4 Dicarbamates, 25:A25; 32:PT32 1,2-di-2,4-Dichlorophenyl Ethanolamine, 16:P120; 27:A43 Dihydrostreptomycin, 9:P68 Dipenicillin V, 8:P58 Dithiobiuret, 4:P21 Diurethans, 13:P94 Dopamine, 27:A43 Elephantiasis Scroti, 4:P24 Epinephrine, 22:A4; 25:A27 Ethylene Dibromide, 17:P129 Fatty Acid Amides, 31:PT24; 31:PT28 Gamma-Ami nobutyric Acid (Gaba) , 14:P102; 14:P104; 25:A27 Glomerular Nephritis, 6:P42; 17:P126 Glutamate, 26:A37 Glycinamides, 29:PT1 ; 29:PT3; 29:PT4; 29:PT5; 29:PT7; 29:PT8; 30:PT11; 30:PT12; 30:PT13; 30:PT14; 30:PT16; 30:PT17; 30:PT18; 30:PT21; 31:PT22; 31:PT23; 31:PT27 Goitrogenic Compounds, 4:P20; 22:A1 Ground Substance, 7:P45; 20:M2 Heparin, 4:P24; 4:P28 22: A3 Hexamethylenimine, 11:P77 Histamine, 15:P117 Hyaluronate, 7:P51 Hyaluronic Acid, 4:P23 Hyaluronidase, 5:P30; 5:P32; 5:P33; 5:P34; 5:P35; 5:P36; 5:P37; 6:P38; 6:P39; 6:P44; 7:P46; 7:P51; 8:P60; 13:P95 Hydrated Alumina Powder, 6:P41 Hydrofluoric Acid, 2:P9 Hydroquinones, 20:M1 Hydroxy-Alkyleneimino-Diacetamides, 31:PT30 5-Hydroxytryptamine, 14:P109; 15:P110 Hypercholesterolemia, 6:P43; 7:P49 Hyperlipemia, 9:P65; 9:P70; 23:A11 Hypophysectomy, 8:P56 Hypothalamus, 13:P97 Iminodipropionitrile, 12:P88; 24:A17 Imipramine, 13:P91 Imnunity, 20: M2 Indoles, 25:A26 Inflammation, 6:P44 Iodine, 4:P25 Kallikrein, 13:P95 L-DOPA, 15:P112 Lead, 2P5 Lipemia Clearing Reaction, 23: A1 3 Lipid Mobiliz...., 9:P64; 10:P72; 10:P73; 10:P74; 10:P75; 11:P78; 11:P80; 11:P82; 12:P84; 12:P86; 12:P87; 20:M6; 20:M7; 31:PT31 Lipid Mobilizing Peptide, 20: M7 Lipid Nephrosis, 6:P42 Reference Notes: Collection of Papers (P), Monographs and Excerpts (M), Abstracts (A), and Patents (PT) -37- ------- Liver, 3:P13; 11:P80 Lymphocyte, 24:A21 Magnus Method, 3:P15 Malate, 26:A37 Mephentermine, 7:P52; 8:P53; 23:A9 Meprobamate, 11:P80; 12:P89; 24:A19 Metal Alkyls, 2:P2 Metyrapone, 16:P119 Monourethans, 13:P94 Morphine, 13:P99 Mucopolysaccharides, 23:A1 3 Muscarinic Synapses, 13:P97 Muscle Receptors, 26:A36 N-dipropyl Acetic Acid, 16:P120 N-n-propylurea Derivatives, 10:P76 Nephrosis, 6:P42; 7:P51 Nicotine, 12:P90; 14:P106 Nicotinic Acid Ester, 31:PT30 Norepinephrine, 14:P106; 27:A43 O Oncogenic Virus, 16:P118 Oxethazaine, 13:P96; 13:P98 PBB (Polybrominated Biphenyls), 17:P130; 18:P132; 18:P135 PDHA (Partially Depolymerized Hyaluronic Acid), 7:P47 Penicillin V, 8:P58 Pentlenetetrazol Antagonists, 25:A27 Pentobarbital, 24:A19 Pentylenetetrazol, 14:P103 Peptide, 20:M7 Permeability, 5:P29; 5:P30; 5:32; 8:P54; 8:P56; 9:P67; 12:P85 Ph4/3, 14-.P108 Phenoselenazines, 24:A22 Phenothiazines, 23:A10; 23:A15; 24: A18; 24:A19 Plasma Lipid Mobilizing Factor, 10:P72, 10:P73 Polyhydric Alcoholchloral Hemiacetals, 23:A14 Promazine, 11:P79; 11:P83; 12:P89; 24: A1 6; 25:A24 Propanediols, 25:A25 Propionamides, 10:P71 Pulmonary Edema, 24:A19; 25:A23 Purpura, 4:P25 Quinones, 20: M1 R Reducing Agents, 2:P8 Renal Calculous Disease, 7:P46 Renal Lithiasis, 6:P38; 6:P39; 6:P40 Reserpine, 13:P99 Rous Chicken Sarcoma, 4:P23 Salicylates, 4:P26 Sarcoma 37, 5:P35 Sarcoma, 4:P23; 16:P123 Selenium, 3:P17; Serotonin, 15:P117; 25:A27; 25: A30? 27:A43 Serum Albumin, 8:P59 Serum Disease, 4:P22; 4:P26; 5:P36 Sodium L-Glutamate, 14:P104 Sodium Polyanhydromannuronic Acid Sulfate, 9:P66; 9:P69 Sodium Tetraphenylboron, 15:P115 Sollmann, Torald, 13:P100; 14:P101 Steroids, 5:P29; 5:P30; 5:P32; 7;P45 Stibines, 2:P3 Streptociccal Hyaluronic Acid, 7:P48 2-Substituted 1,3-Propanediols, 25:A25 Sulfated Pectic Acid, 30:PT19 Reference Notes: Collection of Papers (P), Monographs and Excerpts (M), Abstracts (A), and Patents (PT). -38- ------- Sympathomimetic Amine, 8:P53; 23: A9; 23:A12 Synovial Membrane, 5:P30; 8:P54; 8:P56 T Tertiary Butyl Amines, 30:PT20 Tetraphenylboron, 15:P115; 16:P121; 16:P122; 26:A35; 26:A37; 26:A40; 27:A43 Thryoid Adenomas, 3:P17 Tin, 3:P11 Trachealis Muscle, 18:P133 Trichloroethylene, 3:P13 Trimethyl Bismuth, 2:P1 Trimethylstilbine, 2:P2 O Ulcers, 9:P66; 9:P69 Urinary Calculi, 2:P4 Urinary Colloids, 6:P39; 7:P46 V Vasoactive Drugs, 15:P111 Vinylidene Chloride, 17:P127; 17:P128 Vitamin A, 27:A44 Vitamin C, 2:P5 Reference Notes: Collection of Papers (P), Monographs and Excerpts (M), Abstracts (A), and Patents (PT) -39- ------- |