540/RS-87-135
GUIDANCE FOR THE
REREGISTRATION OF PESTICIQE
^CONTAINING
METHYL
S€HAUGN£SSY.NO.
AS THE ACTIVE INGREDIENT
CAS. HO. 298-OQ-Q
EPA CASE
EPA 540/RS-87-135
-------
TABLE OF CONTENTS
I. Introduction
II. Chemical(s) Covered by this Standard
A. Description of Chemical
B. Use Profile
III. Agency Assessment
A. Summary
B. Preliminary Risk Assessment
C. Other Science Findings
D. Tolerance Reassessment
IV. Regulatory Position and Rationale.
A. Regulatory Positions
B. Criteria for Registration
C. Acceptable Ranges and Limits
D. Required Labeling :
• r - .
V. Products Subject to this Standard
VI. Requirement for Submission of Generic Data
A. What are generic data?
B. Who must submit generic data?
C. What generic data must be submitted?
D. How to comply with DCI requirements
E. Procedures for requesting a change in protocol
F. Procedures for requesting extensions of time
6. Existing stocks provisions upon suspension or
cancellation
VTI. Requirement for Submission of Product-Specific Data
VIII. Requirement for Submission of Revised Labeling . . . .
IX. Instructions for Submission
A. Manufacturing use products (sole active)
B. Manufacturing use products (multiple active)
C. End use products
D. Intrastate products
E. Addresses
-------
APPENDICES
I. DATA APPENDICES
Guide to Tables
Table A
Table B
Table C
II. LABELING APPENDICES
Summary of label requirements and table
40 CFR 162.10 Labeling Requirements
/
Physical/Chemical Hazards Labeling Statements
Storage Instructions
i
Pesticide Disposal Instructions
•*•
Container Disposal Instructions
III. USE INDEX APPENDIX
IV. BIBLIOGRAPHY APPENDICES
Guide to Bibliography
Bibliography
•
V. FORMS APPENDICES
EPA Form 8580-1 FIFRA 3(c)(2)(B) Summary Sheet
EPA Form 8580-6 Certification of Attempt to Enter Into an
Agreement with Other Registrants for Development
of Data
EPA Form 8580-4 Product Specific Data Report
EPA Form 8570-27 Formulator's Exemption Statement
ii
-------
I. INTRODUCTION
EPA has established the Registration Standards program
in order to provide an orderly mechanism by which pesticide
products containing the same active ingredient can be reviewed
and standards set for compliance with FIFRA. The standards
are applicable to reregistration and future applications for
registration of products containing the same active ingredient.
Each registrant of a product containing an active ingredient
subject to this Standard who wishes to continue to sell or
distribute that product must bring his product and labeling
into compliance with FIFRA, as instructed by this Standard.
Pesticides have been grouped into use clusters and will be
reviewed on the basis of a ranking scheme giving higher
priority to (1) pesticides in clusters used on food and feed
crops; and (2) pesticides produced in large volumes.
The Registration Standards program involves a thorough
review of the scientific data base underlying a pesticide's
registration. The purpose of the Agency's review is to reassess
the potential hazards arising from the currently registered
uses of the pesticide; to determine the need for additional
data on health and environmental effects; and to determine
whether the pesticide meets the "no unreasonable adverse
effects" criteria of FIFRA.
In its review EPA identifies:
1. Studies that are acceptable to support the data require-
ments for the currently registered uses of the pesticide.
-------
2. Additional studies necessary to support continued
registration. The additional studies may not have been required
when needed to replace studies that are now considered inadequate.
3. Labeling revisions needed to ensure that the product is
not misbranded and that the labeling is adequate to protect
man and the environment.
The detailed scientific review, which is not contained in
this document, -but is available upon request , focuses on
the pesticide active ingredient. The scientific review
/
primarily discusses the Agency's evaluation of and conclusions
from available data in its files pertaining to the pesticide
active ingredient. However, during the review of these data
the Agency is also looking for potential hazards that may be
iassociated with the end use products that contain the active
ingredient. The Agency will apply the provisions of this
Registration Standard to end use products if necessary to
protect man and the environment.
The Agency's reassessment results in the development of its
regulatory position which is contained in Section IV of this
Standard. Based on this regulatory position, the Agency may
prescribe a variety of steps to be taken by registrants to
maintain their registrations in compliance with FIFRA.
The scientific reviews are available upon request from the
Information Services Section, Room 236, CM-2, 1921 Jefferson
Davis Highway, Arlington VA 22202 (703-557-4453). Ninety
days after the issuance of this standard, the reviews may be
purchased from the Technical information Service, 5285 Port
Royal Road, Springfield VA 22161.
-------
These steps may include:
1. Submission of data in support of product registration;
2. Modification of product labels;
3. Modifications to the manufacturing process of the
pesticide to reduce the levels of impurities or
contaminants;
4. Restriction of the use of the pesticide to certified
applicators or other specially trained individuals;
5. Modification of uses or formulation types; or
6. Specification of packaging limitations.
Failure to comply with these requirements may result in
the issuance of a Notice of Intent to Cancel or a Notice of
Intent to Suspend (in the case of failure to submit data).
In addition, in cases in which hazards to man or the
environment are identified, the Agency may initiate a special
review of the pesticide in accordance with 40 CFR Part 154 to
examine in depth the risks and benefits of use of the- pesticide.
If the Agency determines that the risks of the pesticide's
use outweigh the benefits of use, the Agency may propose
additional regulatory actions, such as cancellation of uses
of the pesticide which have been determined to cause unreasonable
adverse effects on the environment.
EPA has authority under the Data Call-In (DCI) provisions of
FIFRA sec. 3(c)(2)(B) to require that registrants submit data
to answer our questions regarding the chemical, toxicological,
-------
and environmental characteristics and fate of a pesticide.
This Registration Standard lists the data EPA believes are
necessary to resolve our concerns about this pesticide.
These data are listed in the Tables A, B, and C in Appendix I.
Failure to comply with the DCI requirements enumerated in
this Registration Standard may result in issuance by EPA of a
Notice of Intent to Suspend the affected product registrations.
Registrants are reminded that FIFRA sec. 6(a)(2) requires them
to submit factual information concerning possible unreasonable
adverse effects of a pesticide at any time that they become
aware of such information. Registrants should notify the
Agency of any information/ including Interim or preliminary
results of studies, if those results suggest possible adverse
effects on man or the environment. This requirement continues
as long as the products are registered by the Agency.
II. CHEMICAL COVERED BY THIS STANDARD
A. Description of Chemical
The following chemical is covered by this Registration
Standard: ~
^
Common Name: Methyl Parathion
\
Chemical Name: 0,0-dimethyl-0-4-nitrophenyl phosphorothioate
CAS Number: 298-00-0
OPP (Shaughnessy) Number: 053501
Empirical Formula: CgH1005NPS
-------
Trade Names 0,0-dimethyl 0-(4-nitrophenyl) phosphorothioate;
and Other
Names: 0,0-dimethyl O-(p-nitrophenyl) phosphorothioate;
parathion-methyl; metaphos, Cekumethion;
Devithion; dimethyl parathion; E601;
Folidol M; Fosferno M5O; Parataf; Paratox;
Partron M; Penncap M; Tekwaisa; Wofatox;
Hetacide; Bladan M; Metron; Dalf; and
Nitrox 80.
Physiochemical Solubility: Soluble in most organic solvents
and slightly soluble in aliphatic
hydrocarbons. Practically
insoluble in water (55-60 mg/liter).
Compatible with most other pesticides
except alkaline materials.
B. Use Profile
Methyl parathion is a broad-spectrum, non-systemic organo-
phosphate insecticide registered for use to control -many
insects as well as mites and tadpole shrimp. Registered sites
include terrestrial food crops (field, vegetable, and tree
fruit and nut crops), terrestrial nonfood crops (tobacco and
ornamentals}, forestry (including Christmas tree plantations),
\
an aquatic food crop (rice), and terrestrial noncrop sites.
Methyl parathion is predominantly used on field crops. Usage
on field crops accounts for 96.3 percent of the 8.2 million
pounds of active ingredient used on a typical year basis.
Total annual usage on vegetable crops is 3.5 percent, fruit
-------
crops account for 0.2 percent, and usage on non-agricultural
sites account for 0.1 percent.
Methyl parathion is formulated in combination with carbaryl,
parathion, Bacillus thurinaiensis var. kurstaki. zineb, maneb,
endosulfan, copper plus sulfur, methoxychlor, malathion,
toxaphene, endrin, EPN, permethrin, methomyl, and azinphosmethyl.
Single active ingredient formulations consist of 2.0 and 2.5%
dust (D), 25 and 40% wettable powder (WP), 2 Ib/gal
microencapsulated (MCAP), 1.5 to 8.0 Ib/gal amulsifiable
concentrate (EC), and a 45.62% emulsifiable concentrate. Methyl
parathion is usually foliarly applied using ground equipment
or aircraft. Methyl parathion is a restricted use pesticide,
and applicators must be certified or under the direct supervision
of certified applicators in order to apply methyl parathion.
Methyl parathion acts by causing irreversible inhibition of
cholinesterase enzyme, allowing accumulation of acetylcholine
at cholinergic neuroeffactor junctions and autonomic aganglia.
*
Poisoning symptoms include headaches, nausea, vomiting, cramps,
weakness, blurred vision, pinpoint pupils, tightness in the
chest, drooling or frothing of mouth and nose, muscle spasms,
coma, and death.
The federal and state registrations for methyl parathion
include the following:
Section 3 registrations — 305 by 82 companies
Intrastate (CFR 162.17) registrations — 86 by 34 companies
Special Local Need Section 24(c) registrations — 99
-------
Intrastate producers will be notified through a separate
letter as to how they must comply with the requirements imposed
upon them by this methyl parathion Guidance Document. This letter
will be sent to the affected companies no later than two months
from the issuance of this document.
III. AGENCY ASSESSMENT
A. SUMMARY
The Agency has reviewed the available data relating to
methyl parathion. Numerous data gaps exist for methyl parathion
and few definitive conclusions can be made.' Based on the
available data, the Agency has arrived at the conclusions
summarized below. A detailed discussion of these points can
be found in the remaining sections of the "Agency Assessment"
portion of this Standard.
1. Acute toxicitvt Methyl parathion is highly toxic to
laboratory mammals by all routes of exposure. Although methyl
parathion is a restricted use pesticide with a 48 hour reentry
interval, human poisonings from this pesticide still occur.
However, there is no evidence that the poisonings occur when
all reasonable prcautions are taken. Currently, there are
inadequate methyl parathion exposure data available to conduct
an exposure assessment. In addition, the exposure to methyl
parathion cannot be directly extrapolated from generic exposure
data because of the extra care usually taken when handling
acutely toxic pesticides. Additional data are needed to
-------
/
1
evaluate worker exposure. A more detailed discussion of
these issues can be found in Section B item 1 (Preliminary
Risk Assesment; Acute Toxicity), and Section C item 4 (Other
Science Findings; Worker Exposure).
2. Subchronic toxicitvt Subchronic (3-month) feeding
studies in the rat and dog show cholinesterase as the primary
target for the toxic action of methyl parathion. The No
Observed Effect Level (NOEL) in the rat was 2.5 ppm or 0.25
mg/kg/day. The NOEL in the dog was 0.3 mg/kg/day. A more
detailed discussion can ba found in Section C item 1 (Other
Science Findings; Subchronic Toxicity).
3. Metabolism; The specific metabolism of methyl parathion
in both plants and animals has not been entirely determined.
However, sufficient information is available to identify the
chemical changes necessary for activation and deactivation of
*
methyl parathion. Methyl parathion is activated by an oxidative
desulfuration step that greatly enhances its anticholinesterase
«»
properties, and deactivated by a hydrolytic or oxidative
cleavage that renders the molecule virtually inactive.
4. Reproductive effects: The Agency has evaluated a
two-generation rat reproduction study which it considers
satisfactory under current standards, sixty male and 120
female rats were fed diets containing methyl parathion at
concentrations of 0, 0.5, 5.0, and 25.0 ppm. No treatment-
related effects on the reproductive indices were found. No
gross or microscopic changes were considered to be related to
the treatment. No additional data are required.
-------
5. Teratoaenicitv: The Agency received teratogenicity data
on the rat and rabbit in response to a Data Call-In Notice.
These studies are unacceptable because the conduct and results
of the studies were inadequately reported. These studies may
be upgraded by the submission of additional data. The results
of the studies in the rat suggest that methyl parathion is
embryotoxic and fetotoxic in the rat at 1.0 mg/kg., but not
at the NOEL of 0.3 mg/kg. Maternal toxicity was not established
In this study. No evidence of developmental toxicity was
reported in rabbits treated with methyl parathion at dosages
;
i
up to and including 3 mg/kg/day on gestational days six through
eighteen.
6. Chronic toxicitv; The data from a chronic rat study
indicate that methyl parathion causes retinal and sciatic
nerve damage at a dietary level of 50 ppm. Additional testing
is required because treatment-related functional impairment
of the retina may have occurred at lower doses without structural
changes being detected by the ophthalmoscopic and histologic
examinations employed in this study. Also, incomplete histopath-
ologic evaluation of the sciatic nerve at lower dose levels
precludes the determination of a NOEL for this lesion. A
more detailed discussion may be found in Section B, item 2
(Risk Assesment; Chronic Toxicity).
The Agency also evaluated a one-year dog study in which
purebred Beagle dogs were given a diet containing methyl
parathion at concentrations calculated to provide doses of
0.03, 0.1, or 0.3 mg/kg body weight/day. No compound-related
-------
10
toxicity was evident on the basis of clinical pathology tests
with the exception of apparent mild inhibition of plasma and
red blood cell cholinesterase activity at the 0.3 mg/kg dose
level. This dog study is unacceptable because individual
clinical observations were not reported and because there was
inadequate ophthalmologic evaluation.
7. Oncogenicitv; The Agency has evaluated three rat
studies and one mouse study for this effect. The National
Cancer Institute's (NCI) studies (both rat and mouse) showed
no evidence that methyl parathion induced oncogenicity; however,
because of deficiencies in experimental design, these studies
could not be used as a reliable basis for assessing the onccgenic
potential of methyl parathion.
Two additional rat studies were evaluated. One study was
considered inconclusive, primarily because of incomplete
reporting of histopathologic observations. Additional informa-
tion, including historical control data, is required before
the results of this study can be fully evaluated. The other
rat study was acceptable and no oncogenic effects were noted.
See Section B*ltem 3 for a more complete discussion of oncogen-
icity.
\
8. Mutacrenicitvt To assess the mutagenic potential of a
chemical, the Agency requires a battery of tests to address
three categories of possible genetic effects: 1) gene mutation,
2) structural chromosomal aberrations, and 3) other mutagenic
mechanisms, including numerical chromosome aberrations and
-------
DNA damage and repair. The Agency has received and evaluated
all necessary studies. There is some evidence that methyl
parathion is mutagenic and genotoxic.
9. Tolerance Reassessment: Established tolerances for
residues of methyl parathion are listed in 40 CFR Sections
180.121 (a) and (b). The approach used to establish methyl
parathion tolerances is no longer considered to be acceptable
for several reasons. First, the majority of crop tolerances
are not based on actual scientific crop residue data. Second,
a single tolerance expression was used for both the methyl
and ethyl homologs because methyl parathion and ethyl parathion
originally were considered to be structural homologs, and
residue analytical methods at that time could not differentiate
between the two compounds. Therefore, combined tolerances for
ethyl and methyl parathion were established. Now that an
analytical method has been developed to define each of the
homologs separately, the Agency is requiring the submission
of additional residue data so that separate tolerances can be
established. Future tolerance expressions will include methyl
parathion and its cholinesterase inhibiting metabolites co-
analogs, or oxons).
The theoretical maximum residue contribution for methyl
parathion is 0.7762 mg/day based on a 1.5 kg diet, which is
approximately 800% of the Provisional Acceptable Daily Intake
(PADI). However, this figure is not very meaningful because
of the inadequacy of both the residue and toxicology data. A
-------
12
more detailed discussion may be found in Section D (Tolerance
Reassesment).
10. Ecological effects; Methyl parathion is highly toxic
to aquatic invertebrates and birds and is at least moderately
toxic to other nontarget organisms. The Agency is requiring
residue and population monitoring studies to evaluate potential
adverse effects on fish and wildlife since theoretical calculations
indicate probable adverse effects. Currently, there is little
field evidence to support the predictions of acute and chronic
effects. Endangered species labeling 'is required. Current
label warnings regarding non-target organisms remain in effect.
i
A more detailed discussion may be found in Section B item 4
(Risk Assesment; Ecological Effects) and Section C item 2
(Other Science Findings; Endangered Species Considerations).
B. PRELIMINARY RISK ASSESSMENT
1. Acute Toxieitv: Methyl parathion is highly toxic to
laboratory mammals by all routes of exposure with the'major
effect due to cholinesterase inhibition. The oral L0.n in
9O
rats range from 4.5 to 16 mg/kg. Acute dermal H>50 values
range from 6 to 67 mg/kg. Inhalation LC50 values of 0.12
jng/L for four-hour exposure have been reported in rats. Signs
of acute intoxication are typical of cholinergic. poisoning.
Methyl parathion is classified in Toxicity Category I, the
highest toxicity category.
-------
13
Although methyl parathion is a Restricted-Use pesticide
with a 48-hour reentry interval, cases of human poisonings
associated with the use of methyl parathion still occur.
The most reliable data base on pesticide poisonings is
from California. The California information is considered to
be particularly reliable because California is the only state
which enforces mandatory reporting by physicians of occupational
pesticide poisonings. California also investigates all reported
poisonings and verifies the identity of the pesticide involved.
;
Methyl parathion does not appear on the list of the ten leading
pesticides producing systemic occupational poisonings reported
i
by physicians in California between 1981 and 1985. Methyl
parathion averaged two occupational poisonings per year during
this time period. Only one incident of methyl parathion
poisoning required hospitalization between 1981 and 1985 in
California. The California data base for 1981 through 1984
indicates that the ratio for occupational poisonings for
methyl parathion is much less than the poisoning ratio for
ethyl parathion (3.8 versus 33.0 cases treated by a physician
per million acres treated). Similar differences were found
when the ratios were based upon pounds in use in California
(9.7 versus 30.0 cases treated by a physician per million
pounds used). These figures cannot be interpreted to reflect
inherent toxicity to humans because differences in methods of
application for the two chemicals may affect the ratios. Also,
in order to determine the true risk of poisoning for the current
-------
14
use pattern, figures on the number of people who use ethyl
and methyl parathion and the frequency of such use would be
preferable but are unavailable.
It is not possible to infer what differences would be found
in states other than California although very limited national
data suggest that the differences would be similar. Data
from an Agency survey entitled "National Study of Hospitalized
Poisonings, 1974 - 1976" indicate that the ratio of occupational
hospitalized poisonings (1974 through 1976} to million pounds
reported in use in 1974 was 0.5 for methyl parathion and 9.4
for ethyl parathion. A review of available occupational
poisoning surveys can be used to determine whether a pesticide
is being used safely. The Pesticide Incident Monitoring
System (PIMS), now discontinued, was an attempt at a nation-
wide reporting system. A review of the PIMS data for 1978
showed four entries for methyl parathion poisoning of humans
in an occupational setting. The incidents are provided in
Table 1. In two of the incidents, California pesticide regulations
were violated. Both of these two incidents involved probable
contact with aerial spray drift. The incident involving the
crash of the spray plane did not state the cause of the crash.
The PIMS system is limited because of incomplete reporting.
Most states do not require reporting on incidents. Additionally,
the data base are not adequate to show if the poisonings
occurred when methyl parathion is used according to labeled
directions. PIMS data from 1978 was utilized because 1978 is
a recent year prior to the termination of this system.
-------
15
TABLE 1
1978 PIMS REPORTS OF OCCUPATIONAL
METHYL PARATHION POISONINGS
DATE
5 April
STATE
California
POISONING INCIDENT
30 June
Texas
12 July
California
19 July
17 year old male flagger developed
dizziness after contact with spray
drift during aerial application. The
individual was wearing overalls but no
hat. Methyl parathion was applied at
1 pint/acre. The aerial application
service was cited for failure to
provide medical supervision.
A farmer was dermally exposed to
methyl parathion while working on a
truck. Developed nausea, dizziness,
diaphoresis, headache, and ataxia.
Choiinesterase level was 18 units
(normal 65 - 100). Was treated with
atropine.
26 year old male was moving a
sprinkler line 1/4 mile from a cotton
field sprayed with methyl parathion
earlier in the day. He was able to
smell the pesticide in the air. He
was taken to the hospital with chills,
headache, weakness, dry mouth, nausea,
tenseness, dilated pupils, agitation,
and nervousness. Was treated with
atropine. The company was cited for
not having a restricted materials
permit for methyl parathion*
Mississippi Aerial applicator crashed while
spraying and was soaked with ethyl
parathion and methyl parathion.
Serum cholinesterase was 1.06.
Hospitalized for one day. The
PIMS report did not specify if
ethyl parathion or methyl parathion
exposure were the cause of the crash.
However, poisonings may have been reported nationwide as
parathion without proper identification of which homolog was
involved. Some cases may have been reported simply as parathion
without specification as to whether the poisoning was due to
methyl or to ethyl parathion.
-------
16
Methyl and ethyl parathion are different in toxicity, use
patterns, and formulations and this may explain the differences
in poisoning incidences. Methyl parathion is slightly less
toxic than parathion. Aerial application is the usual method
of application to alfalfa and rice, both of which are major
methyl parathion uses in California. Pilots receive substantially
lower exposures per pound of pesticide applied compared to ground
applicators. The Agency's review of parathion poisonings in
California showed that pilot poisonings were rare. Additionally,
methyl parathion is available in a microencapsulated formulation
which is known to have a lower dermal toxicity than all other
formulations.
Although case reports on accidents indicate that methyl
parathion does present some acute toxicity risk to applicators
and farm workers, experience has shown that the problem may
be correctable through extra care and labeling precautions.
By contrast, in the case of ethyl parathion, there were case
reports indicating that applicators were being poisoned despite
taking all possible protective measures.
2. Chronic Toxici^y; A two-year rat study using the
Sprague-Dawley derived CD strain was conducted in which dietary
concentrations of 0.5, 5, and 50 ppm were given to the rats.
The high dosage (50 ppm) of methyl parathion in this strain
of rats caused retinal and sciatic nerve damage.
Evaluation of the sciatic nerve from high-dose males
indicated a loss of myelinated nerve fibers, increased myelin
-------
17
sheath degeneration, and Schwann cell proliferation. The
lack of adequate histopathologic evaluation of the sciatic
nerve at lower dose levels precludes the establishment of a
NOEL for this lesion.
Methyl parathion treatment also caused retinal atrophy and
posterior subcapsular cataract in high dose females. Because
treatment-related functional impairment of the retina may have
occurred at lower doses without being detected in this study,
the Agency is requiring further testing to evaluate specific
ocular parameters at the lower doses. '
3. Oncoaenicitv: In a two-year study with Wistar rats
(GS00153006), dietary exposure to methyl parathion at a con-
*
centration of 50 ppm (the highest level tested) may have caused
a statistically significant increase in thyroid adenomas among
males. Because of deficiencies in reporting the histopatho-
logic findings of this study, oncogenicity could not be
definitively evaluated from the data provided. Further infor-
«
mation is required, primarily additional historical control
data and a specific characterization of the lesions in question,
to upgrade this Wistar rat study.
No evidence of oncogenicity was found in an acceptable
2-year study in Sprague-Dawley rats (GS00153007), or in the
oncogenicity screening studies conducted by the National
Cancer Institute (NCI) on Fischer F344 rats and B6C3F. mice
(00127239). However, The National Cancer Institute studies
-------
18
are not acceptable because of deficiencies in experimental
design and incomplete reporting of results. Because the
Agency has an acceptable rat oncogenicity study it is not
requiring additional oncogenicity testing in this species
at this time. An additional mouse oncogenicity study is
required.
4. Ecological Effects: Toxicity studies on the technical
grade indicate that methyl parathion is very highly toxic to
birds on an acute oral basis. The LD50 in various species of
birds ranged from approximately 7.5 to 60 mg/kg.' This insecticide
is also highly toxic to avian species by dietary exposure
(LC.Q). The LCgg ranged from approximately 29 to 680 ppm in
a variety of species of birds.
Although laboratory data indicate that methyl parathion
is highly toxic to birds, there are no reports of avian field
kills. However, this does not mean that there have not been
significant kills since in the past most bird kills,-except
for the very massive, go unreported or even unnoticed. The
field studies required by this Standard will allow the Agency
to evaluate acute avian effects resulting from the use of
methyl parathion.
Currently, there are no laboratory data on the direct
effects-of technical methyl parathion on avian reproduction.
Laboratory studies conducted using Penncap-M (an encapsulated
methyl parathion product), however, indicate that at levels
-------
19
up to IS ppm active ingredient (ai), there was no biologically
significant impairment of reproduction or survival. There
was, however, significant depression in brain cholinesterase
activity in the adults.
Preliminary field studies indicate that methyl parathion
may affect avian reproduction, although the effects are in-
direct. Specifically, the available field testing data on
starlings demonstrate that nestling survivability can be
affected by changes in nesting behavior of parents exposed to
methyl parathion and/or depressed food abundance. In that
study, nestling starlings had a mortality rate of 39 percent
although they were not directly exposed to the single aerial
application of the pesticide. Also, the production and survival
of teal fledglings and mallard ducklings was reduced by the
application of methyl parathion. Both the number of broods
and number of duckling per brood were reduced. In addition,
several mallard hens abandoned their nests two days after
treatment of the area. This is a behavioral aberration that
the Agency believes was caused by exposure to the pesticide.
Small pen studies, simulated avian field studies, and
field studies in Skagit Valley (GS00153020 and GS00153021)
indicate that birds exposed to methyl parathion display
changes in breeding behavior. Several other observations
were also noted in these studies: 1.) the birds may die directly
from the pesticide or from diseases caused by increased stress
produced by the chemical, or 2.), the birds may survive but
with a significant depression in brain cholinesterase levels.
-------
20
In summary, EPA is evaluating whether exposure to methyl
parathion, a cholinesterase inhibitor which affects the nervous
system, can result in changes in nesting behavior even though
the chemical may not directly affect reproduction. These
possible behavioral effects may be sufficiently severe to
seriously reduce the overall rate of reproductive success.
Additional field data on the effects of methyl parathion on
reproductive success in passerines, upland gamebirds, and
waterfowl are necessary because it is unlikely that these
effects can be measured in the standard laboratory avian
reproduction study.
Acute oral toxicity studies indicate that methyl parathion
is moderately toxic to microtine rodents (voles). The LD5Q
ranged from approximately 57 to 380 mg/kg in voles. On a
dietary basis, there is sufficient information to characterize
methyl parathion as highly toxic to rats and moderately toxic
to microtine rodents. The LCe0 ranged from approximately 110
to 250 ppm in rats and from around 600 to 900 ppm in voles.
As a result, the Agency is requiring that terrestrial field
studies which monitor birds and mammals be performed. Specific
requirements concerning these studies are listed in the Ecological
Effects data tables.
Methyl parathion is highly toxic to freshwater invertebrates,
in which the LC50 ranged from approximately 0.14 to 33 ppb.
Data indicate that methyl parathion is very highly toxic to
shrimp (it is registered to control tadpole shrimp) and copepods
-------
but only moderately toxic to oysters. The LC50 was around 1
ppb for shrimp and approximately 30 ppb for copepods. Methyl
parathion is moderately toxic to freshwater fish, with the
LC5Q ranging from approximately 2 to 10 ppm. There was a
wide range of toxicity to estuarine fish. Methyl parathion
is highly toxic to spot and to striped bass, but only moderately
toxic to sheepshead minnows.
A comparison of laboratory acute toxicity values for
invertebrates and estimated concentrations in water indicate
/
i
that some invertebrates would receive lethal doses resulting
from both cotton and soybean uses of methyl parathion. The
laboratory chronic data on the reproduction and survival of
invertebrates and the fact that multiple applications of
methyl parathion can be used on a particular site suggest
that chronic effects on invertebrates can also occur.
A comparison of the estimated concentrations in water
with the acute and chronic effects data concerning survival
and growth for fish in laboratory studies, indicate that the
potential effects on fish are inconclusive. However, brain
acetylcholinesterase (AChE) inhibition was observed in blueg'ill
in a field situation. This information suggests that chronic
\
effects can occur to fish populations. Neither invertebrate
nor fish population effects have been adequately studied in
field situations. Since the laboratory data indicate the
potential for risks to fish and aquatic invertebrate communities,
the Agency is requiring aquatic field testing data. Please
-------
22
refer to the Ecological Effects data tables for information
concerning these data requirements.
C. OTHER SCIENCE FINDINGS
1. Subchronic Toxicitvt Rats were fed 0, 2.5, 25, and
75 ppm technical methyl parathion in their feed. Both plasma
and red blood cell (RBC) cholinesterase inhibition were noted
in male and female rats at the 25 and 75 ppm ppm treatment
levels. The NOEL was 2.5 ppm or 0.25 mg/kg/day.
Beagle dogs were fed diets containing 0.3, 1.0, and
3.0 mg/kg for 90 days. The only compound-related effect
noted in the dog was inhibition of plasma and RBC cholinesterase
activity at the mid- and high-dose levels and depression of
brain cholinesterase activity at the 3.0 mg/kg level. No other
compound-related effects were reported. The Lowest Effect
Level (LEL), based on cholinesterase depression, was 1.0
mg/kg/day and the NOEL was 0.3 mg/kg/day.
2. Environmental Fatei Available data are insufficient to
fully assess the environmental fate of methyl parathion and
V
the exposure of humans and nontarget organisms to methyl
parathion. The following data are required to fully assess
the environmental fate and the transport of and exposure to
methyl parathion: hydrolysis studies; photodegradation studies
in water, on soil, and in air; aerobic and anaerobic soil
metabolism studies*; aerobic and anaerobic aquatic metabolism
»
studies; leaching and adsorption/desorption studies;
The aerobic and anaerobic soil metabolism studies are not
required if acceptable anaerobic metabolism studies are
submitted.
-------
23
laboratory and field volatility studies; terrestrial (soil),
aquatic (sediment), forestry, and possible long-term field
dissipation studies; and accumulation studies on rotational
and irrigated crops, fish, and aquatic nontarget organisms.
Degradation! The preliminary data on degradation discussed
below is not core data and were not necessarily obtained with
tests meeting EPA's Guidelines Requirements. Nevertheless,
these preliminary data do provide the following information.
Methyl parathion at 10 parts per million degrades in seawater
with 43% of the methyl parathion applied to the sea water
sunlight. Methyl parathion at 0.04 parts per million on
i
degrades in water of sediment/water systems with a half-life
of about one to three days. In hydrosoil plus sediment, the
half-life for the emulsifiable concentrate is about one to
three days, and the half-life for the microencapsulated form-
ulations is about three to seven days. The term "hydrosoil
plus sediment" refers to a test sample including the dense
material at the bottom of a body of water (hydrosoil) and the
lighter sediment above the hydrosoil. In soil columns, methyl
parathion is mobile in sand, but relatively immobile in sandy
loam, silty clay loam/ and silty loam soils. In aqueous
solution with sandy loam soil, the ratio of concentrations of
methyl parathion in solution to that adsorbed is about 1:5.
Methyl parathion is not likely to contaminate groundwater.
Methyl parathion concentrations in runoff from both bare soil
and turf applied four to five days post-treatment at 5 Ib ai/A
-------
24
were similar, about 0.13 to 0.21 ppm in the runoff water in
each case. However, the volume of runoff was not stated;
9
consequently, a percent of applied methyl parathion cannot be
estimated. In the field, dissipation studies showed that
less than 0.05 ppm remained after 30 days when a 3 Ib/A emul-
sifiable concentrate was applied.
3. Worker Exposure; In 1971, the Agency required exten-
sive protective clothing for mettiyl parathion that included
the use of respirators and waterproof clothing. In 1978, the
Agency classified all formulations of methyl parathion for
restricted use.
Currently, there are insufficient exposure data avail-
able to conduct a quantitative risk assessment. The available
surrogate data may not be comparable to the current methyl
parathion exposure data because workers are extraordinarily
careful when handling methyl parathion. The Agency reviewed
ethyl parathion and mevinphos exposure estimates which are
available in the published literature. When these estimates
were compared to other pesticides which are applied in a
similar fashion, the comparisons indicate that ethyl parathion
and mevinphos produce atypically low exposures. The Agency
believes that exposure to methyl parathion may also be atypically
low. Additional exposure data are required for mixers/loaders,
applicators, and fieldworkers while using methyl parathion.
-------
25
As previously stated, the Agency does not have sufficient
data to quantify occupational exposure to mixer/loaders and
applicators handling methyl parathion. A review of the available
poisoning incidents data suggests that methyl parathion can
be used when the appropriate protective measures are employed.
A similar review of ethyl parathion incidents indicated that
poisonings occurred despite extensive precautions and protective
clothing.
A federal reentry interval of 48 hours for methyl parathion
/ ,
has been established for all crops. California has established
more stringent reentry intervals because reentry presents a
greater problem in California than it does in other areas.
Climate conditions in California such as duration of sunlight
and lack of rain favor the chemical conversion of methyl
parathion to methyl paraoxon, which is much more toxic than
methyl parathion. In other geographical regions, a shorter
reentry interval is justified.
•f
California has established reentry intervals for methyl
parathion of 21 days for peaches and nectarines and intervals
of 14 days for citrus, grapes/ and apples when the application
rate is greater than 1 Ib ai/A. When methyl parathion is
applied at 1 Ib ai/A or less, a 48-hour reentry interval is
imposed. However, because the climatic conditions in Monterey
County, California increase the rate of dissipation of non-
encapsulated methyl parathion, the reentry interval for nonencap-
-------
26
sulated methyl parathion in Monterey County is six' days for
grapes. When microencapsulated methyl parathion formulations
are used for grapes, the reentry interval is 48 hours in all
counties of California.
4. Endangered Species Considerations; Endangered species
labeling is required for certain methyl parathion uses. As
further information becomes available, additional endangered
species labeling may be required by the Agency. This conclusion
has been reached as a result of the Agency's evaluation of
the potential for methyl parathion to 'jeopardize endangered
species which reside in areas where this pesticide is used.
j
This assessment was made in conjunction with analyses of all
pesticides under the generic cluster approach which considers
»
. the risk to endangered species on a crop-by-crop basis. The
Agency believes that the labeling required in this standard
is the most efficient and* effective manner of mitigating
risks to endangered species.
*r
Based on terrestrial residue analysis and aquatic runoff
modeling, it appears that certain, use patterns of methyl
*#
parathion have sufficient exposure to pose a hazard to the
listed species. The Agency's analysis shows a hazard to
endangered and threatened mammals, birds, aquatic inverte-
brates, reptiles, and insects.
The criteria used by the Agency to determine whether a
pesticide poses a risk to the continued existence of an
endangered or threatened species are significantly more stringent
-------
27
than those used for non-endangered specie's. Terrestrial
endangered species are determined to be at risk if pesticide
residue levels are one-fifth of the LC1Q or one-tenth of
the LCgg. Aquatic endangered species are determined to be at
risk if residue levels are one-tenth of the LC10 or one-
twentieth of the LC-Q. By contrast, non-endangered terrestrial
species are determined to be at risk if the residue levels
are greater than or equal to the LC50« Non-endangered
aquatic species are determined to be at risk if residues are
greater than or equal to one-half the
Since 1982, cotton, corn, small grains (wheat, barley,
rye, and oats) , sorghum, soybeans, rangeland, forest, and
mosquito larvicide registrations have been reviewed under the
cluster project. Methyl parathion is registered for some of
these sites. The hazard to endangered species from other
uses of methyl parathion has been determined in two ways: by
review and formal consultation with the Office of Endangered
Species (OES) , and the U.S. Fish and Wildlife Service, and by
examining consultations prepared on other pesticides used on
the same sites and with the same use pattern (s) . The latter
approach is based on the assumption that if a hazard to an
endangered species is identified for a particular site and
use pattern for one pesticide, then the use of another equally
hazardous pesticide on the same site with the same use pattern
may pose a similar hazard. In these investigations, use of
methyl parathion was found to pose potential hazards to the
endangered species listed below.
-------
28
a. Cluster Opinions
The various cluster opinions resulted in the following
jeopardy findings which apply to methyl parathion uses:
1. Crops
Attwater's greater prairie chicken (corn, cotton,
soybeans, sorghum, barley, and wheat)
Aleutian Canada goose (corn, wheat, barley)
Everglade kite (corn)
Masked bobwhite (range and pastureland)
Valley elderberry longhom beetle (corn, barley, wheat)
Delta green ground beetle (corn, small grains)
Kern Primrose sphinx moth (small grains, corn and
soybeans)
/
i ,
i
2. Range and Pastureland
Aleutian Canada goose
California condor
Whooping crane
Masked bobwhite
Santa Cruz long-toed salamander
Eastern indigo snake
Hawaiian goose
New Mexican ridge-nosed rattlesnake
San Marcos salamander
Houston toad
Mississippi sandhill crane
- Wyoming toad
Desert tortoise
Valley elderberry longhom beetle
Kern primrose sphinx moth
Delta green ground beetle
Socorro isopod
Hay'^s Spring amphipods
3. Mosquito larvicides
Yuma clapper rail
California clapper rail
Aleutian Canada goose
Salt marsh harvest mouse
Light-footed clapper rail
California least tern
Hawaiian gallinule
Hawaiian coot
Hawaiian stilt
-------
Mississippi sandhill crane
Socorro isopod
Madison Cave isopod
Whooping crane (Grays Lake population)
Kentucky Cave shrimp
4. Forest
Kirtland's warbler
Red-cockaded woodpecker
b. Other Opinions
The Agency has also examined biological opinions prepared
for other pesticides which are used on the same sites as
methyl parathion. These other pesticides also have similar
i
use patterns and were determined to have met the risk criteria
for posing a hazard to endangered species. Based on these
comparisons, the Agency believes that methyl parathion would
also jeopardize the endangered species listed under each of
the following pesticides. These species are included in the
endangered species labeling found in Section IV.0. of this
document.
Species in Jeopardy (assumptions of jeopardy)
4*
Tralomethrin (cotton)
San Marcos salamander
Texas blind salamander
Houston toad
Carbosulfan (apples and pears)
Valley elderberry longhom beetle
Blunt-nosed leopard lizard
Aleutian Canada goose
Santa Cruz long-toed salamander
-------
31
d. Remaining Uses
Methyl parathion is registered for several uses that
have not been reviewed in the cluster project or in registra-
tion submissions for other chemicals. It is unlikely that
these future crop reviews will add endangered species to the
list thus far established because of the broad geographical
distribution of the crops already reviewed.
Endangered species labeling statements are included in the
section of this document entitled "Required Labeling —
Environmental Hazards Statement" and "Required Labeling —-
Endangered Species Restrictions". There is one label statement
for crops, one for pasture/rangeland, and one for mosquito
larvicide uses. The label statements for crops and pasture/
rangeland indicate that the user must obtain the EPA Endangered
*
Species Bulletin before using a methyl parathion product on
that site. The mosquito larvicide products do not contain a
reference to an EPA Endangered Species Bulletin. Mosquito
larvicides are applied by mosquito abatement districts which
will be required to contact endangered species specialists
for guidance prior to use.
D. TOLERANCE REASSESSMENT
1. Residue Data
Tolerances have been established for residues of methyl
parathion in a variety of raw agricultural commodities [40
CFR 180.121 (a) and (b)]. 40 CFR 180.121 (a) includes residues
-------
30
Chlorpyrifos (alfalfa)
Houston toad
Aleutian Canada goose
Carbofuran (rice, peanuts, grains)
Aleutian Canada goose
Attwater's greater prairie chicken
Kern primrose sphinx moth
Oxyfluorfen (non-crop)
Listed insects
Houston toad
Wyoming toad
San Marcos salamander
*
c. Non-jeopardy decisions
Biological opinions prepared for the pesticides listed
below did not indicate that they would jeopardize any endangered
species as a result of their use on designated crops. The
Agency has therefore concluded that the use of methyl parathion
on the crops listed below would not jeopardize endangered
species.
Carbofuran
Tobacco Sugarbeets Grapes
Peppers Potatoes
Strawberries Sweet potatoes
Chlorpyrifos
Broccoli Cabbage Tomatoes
Brussel sprouts Rutabagas Citrus
Nectarines Sunflowers
Aldicarb
Tomatoes Citrus
-------
32
of ethyl parathion and its methyl homolog (methyl parathion),
whereas 40 CFR 180.121 (b) includes tolerances for residues
of methyl parathion but not for ethyl parathion. The tolerance
expression in 40 CFR 180.121 (a) included both the methyl and
ethyl homologs of parathion because these homologs were not
distinguishable by the analytical methodology (colorimetric)
available at that time. However, current gas chromatographic
analytical methods are capable of distinguishing between
these two compounds, and, therefore, the Agency is now requiring
separate tolerances.
/
i
The majority of crop tolerances for methyl parathion
.were established by the Pesticide Spray Residue Hearings held
in the 1950s and are based on estimates of residues which
would probably^ be present following pesticide treatment to
the crop; the tolerances are not based on actual scientific
crop residue data. The existing tolerances do not take into
consideration the metabolites of the parent compounds. Therefore,
the Agency is also requiring that methyl parathion to'lerances
be expressed in terms of the parent compound and any identified
major metabolites.
Crop residue data and plant and animal metabolism data
are required by this Registration Standard. Once the Agency
has received and reviewed these data, it will determine whether
additional tolerances for animal products (meat, milk, and
eggs) are required. As indicated in Table A, crop group
-------
33
tolerances are not appropriate at the present time since
additional key residue data are needed for representative
members in each crop group.
2. Toxicology Data
The current provisional acceptable daily intake (PADI)
for methyl parathion is 0.0015 mg/kg/day. This figure is
based on a subchronic (90 day) dog study with a NOEL of 0.3
mg/kg/day (12 ppm in the diet); the safety factor was set at
200, in accordance with previous standard practice. The
present PADI is temporary and will be modified (or an ADI
will be established) when additional required data are received
and evaluated. The Theoretical Maximum Residue Contribution
(TMRC) is approximately 0.78 mg/day based on a 1.5 kg diet.
This is approximately 800 percent of the PADI for the general
population, based on established tolerances.
This assessment may greatly exaggerate dietary exposure.
The assessment is based on several worst-case assumptions:
*
that methyl parathion residues are equal to established tolerance
levels, that 100 percent of the crop is treated with methyl
parathion, and that there is no degradation of residues after
harvesting. It has been the Agency's experience that pesticide
residue levels on crops are usually below established tolerances.
In addition, much less than 100 percent of registered crops
are treated with methyl parathion, and, in fact, very little
methyl parathion is used on crops that contribute significantly
-------
to the TMRC. Before the Agency can assess methyl parathion's
risk from dietary exposure, additional toxicological data are
needed. Data from recent chronic feeding studies in rats
suggest that a new, lower NOEL may need to be established
based on either cholinesterase effects or systemic effects,
whichever occurs at a lower level. The Agency is requiring
additional data to determine a NOEL for eye toxicity based on
possible functional retinal impairment in the dog and rat.
Data on sciatijc nerve degeneration in the rat must also be
provided.
i
IV. REGULATORY POSITION ANf> pAT^ONAT^j
i
A. REGULATORY POSITIONS AND RATIONALES
Based on review and evaluation of all available data on
methyl parathion, the Agency has made the determinations
below. Refer to Section IV.D. for specific language for label
revisions.
Special Review
1. The Agency will not conduct a Special Review for methyl
parathion at this time.
Rationale; Although methyl parathion is a highly toxic
f
chemical, a Special Review will not be conducted for several
reasons. First, although methyl parathion has been shown to
cause retinal and sciatic nerve damage at high doses (50 ppm
in rats) adequate exposure data are not available to evaluate
-------
35
risk. As a result, there is no basis upon which to determine
whether these effects are likely to occur in humans. In
addition, the available data do not suggest that retinal and
*
sciatic nerve problems are being experienced in human populations.
Thus, the Agency cannot conclude at this time that the use of
methyl parathion poses risks of retinal and sciatic nerve
damage. However, because of the evidence of retinal and
sciatic nerve damage observed in laboratory animal studies,
and in view of the numerous data gaps relating to toxicology
and exposure to methyl parathion, the Agency will carefully
review these data being submitted in response to this Registration
Standard to determine if a Special Review is warrented. Second,
although incidences of human poisoning have occurred, they
have not occurred, in the Agency's opinion, frequently enough
to warrent a Special Review. A more complete discussion of
worker safety may be found in Section III, supra. Third,
although methyl parathion is highly toxic to birds and other
aquatic invertebrates and at least moderately toxic to other
non-target organisms, there is little evidence derived from
field investigations to support the predictions. The Agency
is requiring that additional field monitoring studies for
fish and wildlife be conducted. The Agency reserves considera-
tion of Special Review until it has recieved and reviewed
these additional field monitoring studies.
While methyl and ethyl parathion are both very highly
toxic to birds, the regulatory treatment being accorded them
-------
36
by the Agency differs for several reasons. There are many
reported bird mortalities relating to the agricultural use of
ethyl parathion as indicated by field studies and accident
reports from both federal and state agencies. In contrast,
the Agency has not received such reports form methyl parathion.
Restricted Use
2. All methyl parathion products are currently classified
as Restricted Use pesticides, and this classification is being
retained. However, the Agency has modified the Restricted
Use Statement. Certified applicators are now required to be
physically present during application, mixing and loading of
methyl parathion, as well as during repair and cleaning of
the application equipment. Commercial applicators are also
required to ensure that all persons engaged in these activities
under their direct supervision are informed of all precautionary
statements on the label. Finally, the reason or basis for
the restriction is stated; "because of very high acute toxicity
to humans and birds".
Rationale: The acute toxicity of methyl parathion to
s
humans has been well-documented. Because of this concern,
methyl parathion was classified as a Restricted Use Pesticide
in 1978 and a reentry interval was established in 1974. This
concern continues, consequently, the Restricted Use Classifica-
tion will remain in effect, with modifications designed to
provide additional protection. The Agency has imposed the
-------
37
additional requirements in order to increase the level of
protection afforded to mixer/loaders and applicators.
Because of the inherent dangers which could arise as a result
of exposure during application, splashing and spillage during
mixing and loading, and during repair and cleaning of application
equipment, certified applicators are taught safe methods by
which to use pesticides. Untrained workers are less likely
to be aware of the acute hazards associated with methyl parathion.
A requirement stipulating that a certified applicator must be
physically present during these procedures will increase
supervision as well as improve compliance with label requirements.
The Agency requires that commercial applicators ensure that
persons under their direct supervision who are involved in
applying, mixing and loading of the pesticide and/or repair
and cleaning of application equipment are informed of precautionary
usage statements found on the methyl parathion label. This
regulation ensures that persons who may come into contact
with the methyl parathion are aware of and can comply with
required measures designed to protect their health.
Additional Tolerances
3. The Agency will not accept any additional tolerances,
either group or otherwise. No new food uses or tolerances
will be granted until the Agency has received both data to
support an acceptable daily intake and to support a full
tolerance assessment.
-------
38
Rationale; The Agency has established a policy that
precludes the establishment of tolerances or new uses if the
toxicology data base is substantially incomplete and if the
pesticide's TMRC significantly exceeds the Acceptable Daily
Intake (ADI). The Agency becomes very concerned whenever a
the Theoretical Maximum Residue Concentration is greater than
100 percent of the ADI. First, the Agency focuses upon ways
in which the TMRC .can be decreased, thereby lowering the
percentage of the TMRC that is utilized by the ADI. If this
cannot be accomplished, tolerances must be revoked and uses
must be cancelled.
i
Exposure Data
j.o 4. The Agency is requiring human exposure and biological
monitoring studies.
Rationale: A review of available mixer/loader and applicator
data for methyl parathion indicates that such studies are
»
necessary. The exposure data in the Agency's files are not
adequate to conduct an exposure assesment. Surrogate data
are available to perform the exposure assessments for aerial,
ground boom, and airblast applications of liquid and wettable
powder formulations for typical pesticides. However, the use
of surrogate data for evaluating notoriously highly toxic
chemicals such as methyl parathion are not realistic, since
these chemicals are usually handled much more carefully than
less toxic pesticides. For example, when the Agency compared
-------
39
average exposures of ethyl parathion and mevinphos to the
exposures of other pesticides which are applied by similar
methods and at similar application rates, average ethyl parathion
and mevinphos exposures were lower than would normally be
expected. Therefore, actual exposure data for methyl parathion
are being required.
The Agency is requiring both passive dosimetry and biological
monitoring studies for each formulation of methyl parathion.
The exposure and biological monitoring studies are required for
aerial application, ground boom application, and air blast
application. Mixer/loader exposures should be evaluated with
i
both open pour and closed loading systems when applicable.
Reentry Interval
5. The Agency is not changing its current Federal reentry
interval of 48 hours at this time.
Rationale; On February 28, 1985, the Agency issued a Data
Call In (DCI) Notice notifying registrants that these data
must be submitted within 18 months. The Agency has received
data in response to this request; this data is currently being
reviewed. When this review is complete, a reentry interval
will be established. The current reentry interval was established
without supportive data, however the Agency believes that this
reentry interval is adequate until the new data is reviewed
and new reentry interval(s) is established.
-------
40
Protective Clothing and Equipment:
6. Existing Federal labeling requires the use of protective
clothing and equipment during application of methyl parathion.
The type of protective clothing and equipment required includes
waterproof pants, coat, hat, rubber gloves and boots, safety
goggles, and a mask or respirator approved for use with parathion.
The Agency has determined that this full body protective
clothing and j^guipment must be used during mixing/loading
operations and during field repair and cleaning of equipment
used to mix, load, and apply the pesticide. In addition, this
protective clothing and equipment would also be required if
treated fields are re-entered prior to the end of the reentry
interval.
Rationale; The Agency has determined that the use of
protective clothing and equipment for mixing/loading operations,
field repair, cleaning of application equipment, as well as for
early reentry into treated fields is needed because of methyl
parathion's high acute toxicity and the associated potential
for high exposure during these activities. Repair and cleaning
of application equipment may involve a risk of spillage or
rupture of lines and hoses, and result in exposure to mixer/
loaders and applicators. By requiring persons engaged in
these activities to wear the protective clothing and equipment
described in Section IV.D. infra, the potential for exposure
will be reduced.
-------
41
Glove permeability studies are needed in order to determine
if the gloves that are in use are adequate to protect pesticide
workers.
Alternative Protective Clothing and Equipment
The modified label provides that alternative protective
clothing and equipment may be worn if mixing/loading is
performed using a closed system, or if application is performed
using an enclosed cab or cockpit. The alternative protective
clothing and equipment is less extensive than that required
in other circumstances.
Rationale; Studies have demonstrated that the use of
closed mixing/loading systems and totally enclosed cabs can
substantially reduce exposure to some pesticides (GS00155025).
The term "totally enclosed cabs" implies that physical
barriers to the outside environment exist and that windows
or louvers are kept closed. Because of the impact (economic
and otherwise) this equipment could impose upon the users of
this pesticide, the Agency has decided not to require its use
at this time. The Agency does, however, wish to encourage
the use of this equipment. The Agency is giving applicators
the option of using less extensive protective clothing and
equipment if closed mixing/loading systems are used. Such
clothing and equipment includes chemical resistant gloves and
apron, and a long-sleeved shirt (or gauntlets and a short-
sleeved shirt) and long legged pants. If application is made
-------
42
using am enclosed cab or cockpit, a long-sleeved shirt and
long-legged pants must be worn. Chemical-resistant gloves
must be available for exiting the vehicle or aircraft.
Human Flaaaers
8. The Agency is prohibiting the use of human flaggers
during aerial application of parathion.
Rationale; Human flaggers face a substantial risk,
either directly or through drift, of being exposed to methyl
parathion because of the nature of aerial application and the
/
changing wind conditions. Incidence data also show a number
of poisonings to human flaggers.
Storage and Laundering of Personal Clothing
9. Existing labeling for methyl parathion contains
numerous directions regarding personal hygiene and cleaning
of protective clothing and equipment after working with the
pesticide. The instructions also add a requirement that
personal clothing which is worn while working with methyl
parathion be stored and laundered separately from other
household items.
*
Rationale; This requirement is intended to prevent
secondary poisonings of workers and other household members.
National Pesticide Telecommunications Network
10. The Agency has added the telephone number of the
National Pesticide Telecommunications Network to the label.
This number is (1-800-858-7378).
-------
43
Rationale; The telephone number is included in order to
provide an additional source of first aid information in the
event of an accident.
Sprav Drift Data Requirements
11. Droplet Spectrum and Spray Drift Field Evaluation
tests are required. The droplet spectrum study must be performed
to reflect the commonly-used nozzle and other equipment types
which are used in the application of methyl parathion to
cotton, fruit and nut trees, and forests. The spray drift
field -evaluation must be performed to reflect the commonly-
used application equipment, use patterns, and typical locations
of use (including different weather factors). The spray
•
drift field evaluation should specifically be conducted on
cotton.
Rationale: The Agency is concerned about hazards to
nontarget organisms (fish and wildlife, domestic animals and
«r
humans) caused by drift from aerial and mist-blower applications
of methyl parathion. These tests are required because of the
toxic nature of methyl parathion and because the methods used
to apply methyl parathion (mist blower and aerial) may lead
to exposure of bystanders and wildlife. These tests will
indicate the extent of possible drift of this chemical from
normal applications and the data from these tests will enable
the Agency to evaluate the potential for drift. The required
testing using cotton as a site is being required because
cotton is one of the major uses of methyl parathion.
-------
44
Waiver of Acute Toxicitv Studies
12. Although the Agency does not have guideline data
for certain acute studies such as dermal sensitization,
primary dermal irritation, and primary eye irritation
tests, the Agency is not requiring these data at this
time.
Rationale; The Agency is not requiring these data
because of the well-known highly toxic nature of methyl
parathion. This toxicity would overshadow any possible
t
irritant or sensitization properties. Additional testing
would not alter the toxicity category-or classification of
methyl parathion.
Endangered Species
13. The Agency is requiring endangered species labeling
for certain uses of methyl parathion.
Rationale: The Agency has evaluated the potential for
methyl parathion to jeopardize endangered species in areas
where this pesticide is used. Analyses of terrestrial residue
and aquatic runoff modeling indicate that certain use patterns
of methyl parathion have sufficient exposure to pose a hazard
to endangered/threatened species.
Separate Tolerances
14. The Agency is requiring that separate tolerances be
established for residues of ethyl parathion and methyl parathion,
-------
45
Rationale; In the 1950's, the tolerance expression
included both ethyl and methyl parathion because these homologs
were not distinguishable by the analytical methodology (colori-
metric) available at that time. The current gas chromatographic
analytical methods are capable of distinguishing between
these two compounds and, therefore, the Agency is requiring
separate tolerances for these two chemicals.
15. Tolerances must be established for residues of methyl
parathion in cattle, goats, hogs, horses, poultry, and sheep.
[40 CFR 180.121], !
Rationale; The need for and magnitude of the residue
tolerances for methyl parathion in livestock products has not
been assessed for several reasons. First, the nature of the
residue in ruminants and poultry has not been elucidated.
Second, the nature and magnitude of the residues in the raw
agricultural and processed feed commodities have not been
adequately determined. Third, there are no available feeding
4*
studies. Currently, methyl parathion is not registered for
direct use on livestock. When the requested data are received
and evaluated, data needs and tolerance proposals for residues
in animal commodities will be determined. The TMRC will also be
recalculated.
Tolerances for residues in these animals must be established
for safety reasons, as all of these animals are used for human
consumption. Currently, there are no established tolerances
for these animals.
-------
46
Residue Data
17. Residue data and appropriate studies involving food
preparation (washing, peeling, cooking) are required.
Rationale; This information is necessary in order to
conduct an appropriate dietary assessment. Additional residue
data is necessary because in the process of food preparation,
residue may be lowered (depending upon the type of preparation
involved).
/
Tolerance Changes
18. The Agency has determined that certain additional
tolerances be obtained or modified. Specific modifications
;and their individual rationales are described below.
a. Separate tolerances should be established for snap,
lima, and dry beans.
Rationale: Tolerances were not established for these
commodities. Tolerances for these commodities were originally
described in the crop grouping tolerance scheme which has
since ended.
b. Separate tolerances should be established for suc-
culent and dry peas.
Rationale; Subdivision 0 of the Pesticide Assessment
Guidelines requires the establishment of separate tolerances
for succulent and dry peas.
-------
47
c. Data and tolerance proposals must be submitted for
residues in or on bean vines and hay, pea straw, and soybean
forage and straw along with pregrazing intervals for pea
vines, bean vines, and soybean forage; alternatively, a feeding
and grazing restrictions for these commodities must be proposed.
Rationale; Because these commodities are fed to animals,
tolerances need to be established for them. Subdivision 0 of
the Pesticide Assessment Guidelines requires the establishment
of tolerances for feed commodities.
/
t
d. The tolerance for residues in or on "summer" squash
must be revoked.
Rationale: This tolerance must be revoked because there
is no registered use on "summer" squash per se. Additionally,
the tolerance for residues in or on squash encompasses "summer"
squash.
e. Separate tolerances must be proposed for residues in
or on field corn grain and sweet corn (kernel plus cob with
husks removed).
Rationale; Separate tolerances for these two types of
corn are necessary because significant major differences occur
in the growing seasons and cultural practices for sweet corn
as compared to field corn.
-------
48
f. A permanent tolerance must be proposed for residues
in or on rye grain.
Rationale; The interim tolerance on rye has been revoked.
There exists a registered use for methyl parathion on rye, but
this use is not presently covered by a tolerance. Registrants
must request a permanent tolerance for rye. Registrants must
submit appropriate data for a tolerance on rye grain. Appropri-
ate food and £eed .additive tolerances are also necessary if
milling data indicates the necessity for them.
/ i
g. Pregrazing intervals for forage and tolerances are
needed for barley forage, hay, and straw; oat forage, hay,
and straw; rice straw; rye forage, hay and straw; and wheat
forage, hay and straw. However, data submitted for wheat can
m. »
be translated to barley, oats, rice and rye. Alternatively,
feeding and grazing restrictions must be proposed for these
commodities.
Rationale; Tolerances for these items are necessary
because they were never established for these registered
uses. Pregrazing intervals are required to assure that
s
illegal secondary residues of methyl parathion will not
-result in meat and milk.
h. Pregrazing intervals are also needed for the forages
of corn, alfalfa, clover, sorghum, sunflower, and cotton.
In addition, a pregrazing interval for forage and data and
tolerance proposals for residues in or on peanut hay and
-------
49
forage are needed. Alternatively, feeding and grazing restric-
tions must be proposed for peanut hay and forage.
Rationale; As explained in item number "g" above,
pregrazing intervals are necessary so illegal residues will
not occur in meat and milk products since these commodities
are fed to cattle.
i. Data and/or tolerance proposals are necessary and
are described for specific crops below.
Data and tolerance proposals for residues in or
on fodder and silage are needed.
Data and tolerance proposals for residues in or
on silage and hay are needed for sorghum. Alternative-
ly, feeding restrictions must be proposed for silage
and hay.
Data and a tolerance proposal are needed for residues
in or on alfalfa seed.
Separate tolerances must be established for clover
forage and hay as well as for vetch forage and hay.
Residue data and a tolerance proposal are needed for
peanut hulls.
Data and tolerance proposals for residues in or on
sunflower and cotton forage are needed.
Data depicting residue and the nature of pyrolysis
products levels in tobacco smoke are needed.
Data and a tolerance proposal are needed for residues
in or on grass hay.
Rationale: The above commodities are deficient in sup-
portive residue data. Subdivision 0 of the Pesticide Assesment
Guidelines provide guidance regarding data and tolerance
requirements for these various commodities.
-------
50
j. Additionally, in regard to residue data and deficien-
cies, the following commodity definitions should be changed
in 40 CFR 180.121 in keeping with presently accepted commodity
definitions:
"Beets (with or without tops)" should be changed to
"garden beet roots".
"Rutabagas (with or without tops)" should instead
read "rutabaga roots".
"Turnips (with or without tops)" should be modified
to -Hturnip roots".
\
"Pea forage" should be changed to "pea vines".
/
/
"Fresh alfalfa" should instead be "alfalfa forage".
Sale of Currently Registered Products
19. While data gaps are being filled, currently registered
manufacturing^use products (MPs) and end use products (EPs)
containing methyl parathion as the sole active ingredient may
be sold, distributed, formulated, and used, subject to the
terms and conditions specified in this Standard. Registrants
must provide or agree to develop the additional data' as specified
in the Data Tables A and B, in order to maintain existing
registrations.
Rationale; Under FIFRA, the Agency does not normally
cancel or withhold registration simply because data are missing
or are inadequate. [See FIFRA, sec. 3(c)(2)(B) and 3(c)(7)]
Issuance of this Standard provides a mechanism for identifying
data needs. These data will be reviewed and evaluated to
determine whether additional regulatory changes are necessary.
-------
51
New food uses will not be processed until the problems
relating to ADI are resolved.
B. CRITERIA FOR REGISTRATION
To be registered or reregistered under this Standard,
products must contain methyl parathion as the sole active
ingredient, bear required labeling, and conform to the product
composition, acute toxicity limits, and use pattern requirements
listed in this section.
C. ACCEPTABLE RANGES AND LIMITS !
1. Product Composition Standard
To be registered or reregistered under this Standard,
manufacturing-use products (MPs) must contain methyl parathion
as the sole active ingredient. Each manufacturing-use product
formulation proposed for registration must be fully described
with an appropriate certification of limits, stating maximum
»
and minimum amounts of the active ingredient and inert
ingredients which are present in products, as well as impurities
found at greater than 0.1 percent.
2. Acute Toxicitv Limits
The Agency will consider registration of technical grade
and manufacturing-use products containing methyl parathion
provided that the product labeling bears appropriate precaution-
ary statements for the acute toxicity category in which each
product is placed.
-------
52
3. Use Patterns
To be registered under this Standard, manufacturing-use
products may be labeled for formulation into end-use products
only for the sites and uses listed below. The EPA Compendium
of Acceptable Uses lists all registered uses, as well as
approved maximum application rates and frequencies.
-Terrestrial, non-domestic, food uses on:
•*-
Alfalfa, almonds, apples, apricots, artichokes,
barley, beans, beets, birdsfoot trefoil (intrastate),
broccoli, brussels sprouts,,cabbage, carrots,
cauliflower, celery, cherry, citrus (intrastate),
clover, collards, corn, cotton, cotton, cucumber,
eggplant, forage grass, garlic (special local need),
gooseberries, grapes, hops, kale, kohlrabi, lentils
(special local need), lettuce, melons, mustard
greens, nectarines, oats, onions, pasture,
peaches, peanuts, pears, peas, pecans, peppers,
plums, potatoes, prunes, pumpkins, rangeland,
rutabagas, rye, safflower, sorghum, soybeans,
spinach, squash, strawberries, sugar beets, sunflowers,
sweet potatoes, tomatoes, turnips, vetch, wheat.
-Terrestrial, non-domestic, non-food uses on:
Tobacco, jojoba (special local need), guayule (special
local need), field grown ornamental flowering plants,
chrysanthemums, daisies, marigolds, stock, forest,
nonagricultural land, wastelands, forest and Christmas
tree plantings (pine).
-Aquatic food crop uses on:
Rice
D. REQUIRED LABELING
All manufacturing-use products and end-use products must
bear appropriate labeling as specified in 40 CFR 162.10, PR
Notice 83-2, PR Notice 73-4, and below. Appendix II and Attach-
ment I contain additional information on label requirements.
-------
53
No pesticide product containing methyl parathion as an
active ingredient may be released for shipment by the registrant
after OfT! I {ggj unless the product bears an amended label
which complies with the requirement of this Standard.
No pesticide product containing methyl parathion as an
active ingredient may be distributed, sold, offered for sale,
held for sale, shipped, delivered for shipment, or received
and (having so received) delivered or offered to be delivered
by any person after FIFE I IQftfi unless the product bears
/
t
an amended label which complies with the requirements of this
Standard.
1. Ingredient Statement
•
The ingredient statement for manufacturing-use products
must list the active ingredient as:
0,O-dimethyl-O-4-nitrophenyl phosphorothioate.
2. Use Pattern Statements
All manufacturing use products must state that they are
intended for formulation into other manufacturing use products
or end use products for those uses accepted by the U.S. EPA.
A limiting factor will be data that support these use patterns.
No use may be included on the label where the registrant
fails to agree to comply with the data requirements in Table
A and B for that use pattern.
-------
54
3. Precautionary Statements
Labels for manufacturing-use products and end use pro-
ducts must bear statements reflecting the compound's acute
human toxicity. All methyl parathion products except micro-
encapsulated formulations with 22% or less active ingredient
are in Toxicity Category I and must bear the signal word
"DANGER". Microencapsulated products with 22% or less are in
Toxicity Catagory II and must bear the signal word "Warning".
The required precautionary associated with this category are
specified in 40 CFR 162.10. Also, refer to PR Notice 73-4
regarding the required graphics, skull and crossbones and
other precautionary labeling requirements that continue to
remain in effect for the Toxicity Catagory I products.
4. Environmental Hazards Statements
The following revised environmental hazard statement must
appear on all MUP labels:
This pesticide is highly toxic to aquatic invertebrates.
Do not discharge effluent containing this product
into lakes, streams, ponds, estuaries, oceans or
public waters unless this product is specifically
identified and addressed in an NPDES permit. Do
„ not discharge effluent containing this product to
sewer systems without previously notifying the
sewage treatment plant authority. For guidance,
contact your State Water Board or Regional Office of
the Environmental Protection Agency.
End-Use Products
Terrestrial Sites
This pesticide is highly toxic to aquatic invertebrates
and wildlife. Birds in treated areas may be killed.
-------
55
Do not apply directly to water or wetlands (swamps,
bogs, marshes and potholes). Runoff and drift from
target areas may be hazardous to aquatic organisms
in adjacent aquatic sites. Do not contaminate
water by cleaning of equipment or disposal of wastes.
Aquatic Sites (Rice)
This pesticide is highly toxic to aquatic invertebrates
and wildlife. Shrimp and other aquatic organisms
may be killed at recommended application rates. Do
not contaminate water by cleaning of equipment or
disposal of wastes.
Aquatic Sites (Mosquito Larvicidel
This pesticide is highly toxic to aquatic invertebrates
and wildlife. Shrimp and other aquatic organisms
in treated waters may be killed. When treating
lakes or other open bodies of water, apply only to
shallow edges. Consult with state fish and game
departments before applying to public waters. Do
not contaminate water by cleaning of equipment or
disposal of wastes.
Bee Precaution Labeling
Labeling for methyl parathion products intended for
outdoor use should bear the following statement:
This product is highly toxic to bees exposed
to direct treatment or residues on blooming
crops or weeds. Do not apply this product
or allow it to drift to blooming crops or
weeds if bees are visiting the treatment area.
Auxiliary statements, to appear in the use directions
for the particular crop or site, are required for the following
crops:
a. Foliar application to alfalfa, peas, or beans:
"Do not apply if the crop or weeds in the treatment
area are in bloom.11
b. Foliar application to corn:
"Do not apply to corn during the pollen shed period.
c. Foliar application to listed fruit trees
(apple, cherry, peach, plum, citrus):
-------
56
"Do not apply when trees or substantial numbers of
weeds in the orchard (grove) are in bloom."
5, Endangered Species Restrictions
Please refer to Attachment I on page 71.
6. Worker Protection Statements
Pursuant to Pr Notice 83-2, for all end-use products/
the general worker protection statements specified in that
notice must appear on the labeling of outdoor agricultural
use products which are applied to crops whose cultural practices
include hand labor. In addition, the following reentry interval
must be stated on the label:
Reentry into treated fields is prohibited for 48
hours after application, unless all protective
clothing and equipment required for early reentry
as described elsewhere on the label are worn.
7. Restricted Use statement
The following "Restricted Use Statement" must appear
on the front panel of all end-use products.
RESTRICTED USE PESTICIDE
Due to very high acute toxicity to Humans and Birds
For retail sale to and use only by certified applicator or
persons under their direct supervision and only for those
uses covered by the certified applicator's certification.
Direct supervision for this product is defined as the
certified applicator being physically present during
application, mixing, loading, repair and cleaning of
application equipment. Commercial certified applicators
must also ensure that all persons involved in these
activities are informed of the precautionary statements.
-------
57
8. Work Safety Rules
The National Pesticide Telecommunication Network is
available for recommendations regarding poisoning management,
emergency treatment, and other information regarding the
toxicity of methyl parathion. The toll free number for the
National Pesticide Telecommunication Network is 1-800-858-
7378.
If handled indoors provide mechanical exhaust ventilation.
Keep all unprotected persons, children, livestock, and pets
away from treated area or where there is danger of drift. Do
not rub eyes or mouth with hands. If you feel sick in any
way, STOP work and get help right away, See First Aid (Practical
Treatment) section.
HANDLE THE CONCENTRATE ONLY WHEN WEARING THE FOLLOWING
PROTECTIVE CLOTHING AND EQUIPMENT:
Wear a protective suit of one or two pieces
that covers all parts of the body except the
head, hands, and feet. Wear chemical resistant
gloves, chemical resistant apron, and chemical *
resistant shoes, shoe coverings, or boots.
Wear goggles or a face shield. Wear a pesticide
respirator approved by the National Institute
for Occupational Safety and Health under the
provisions of 30 CFR part II.
USE ONLY WHEN WEARING THE FOLLOWING PROTECTIVE
CLOTHING AND EQUIPMENT DURING MIXING/LOADING,
APPLICATION, REPAIR, AND CLEANING OF APPLICATION
EQUIPMENT, DISPOSAL OF PESTICIDE AND EARLY
REENTRY INTO TREATED AREAS: protective suit of
one or two pieces covering all parts of the
body except the head, hands, and feet; chemical
resistant gloves; chemical resistant shoes (or
chemical resistant shoe coverings or chemical
resistant boots); goggles or face shield; hood
or wide brimmed hat; NIOSH approved respirator.
-------
58
IF MIXING/LOADING IS PERFORMED USING A CLOSED
SYSTEM, THE FOLLOWING PROTECTIVE CLOTHING AND
EQUIPMENT MAY BE WORN AS AN ALTERNATIVE: long-
sleeve shirt; long-legged pants; chemical resistant
gloves; chemical resistant apron; shoes and socks.
Goggles or face shield must be worn when the system
is under pressure. All other protective clothing
and equipment required for use with open systems
must be available nearby.
IF APPLICATION IS PERFORMED USING AN ENCLOSED CAB
OR COCKPIT, THE FOLLOWING PROTECTIVE CLOTHING
AND EQUIPMENT MAY BE WORN AS AN ALTERNATIVE:
long-sleeve shirt and long-legged pants; shoes and
socks. Chemical resistant gloves must be available
in the cab or cockpit and must be worn during
entry to and exit fro the application vehicle.
All other protective clothing and equipment required
for use during application must be available in
the cab and must be worn when exiting the cab into
treated area. When used for this purpose, contaminated
clothing may not be brought back into the cab
unless in an enclosure such as a plastic bag.
REMEMBER-THIS CLOTHING IS INADEQUATE TO PROTECT YOU
DURING REPAIR AND CLEANING OF APPLICATION EQUIPMENT
AND EARLY REENTRY TO TREATED AREAS I REFER TO
PROTECTIVE CLOTHING AND EQUIPMENT REQUIREMENTS
ABOVE.
IMPORTANT! If pesticide comes in contact with
skin, wash off with soap and water and contact a
physician immediately. Always wash hands, face,
and arms with soap and water before smoking, eating,
drinking, or toileting.
AFTER WORK: before removing gloves, wash them with
soap and water. Take off all work clothes and shoes.
Shower using soap and water. Wear only clean
clothes when leaving job—do not wear contaminated
clothings- Personal clothing worn during work must
be stored and laundered separately from protective
clothing and household articles. Store protective
clothing separately from personal clothing. Clean
or launder protective clothing after each use.
Respirators must be cleaned and filters replaced
according to instructions included with the respirators.
Protective clothing and protective equipment heavily
contaminated or drenched with methyl parathion must
be destroyed according to state and local regulations.
HEAVILY CONTAMINATED OR DRENCHED CLOTHING CANNOT BE
ADEQUATELY DECONTAMINATED. DURING AERIAL APPLICATION,
HUMAN FLAGGERS ARE PROHIBITED.
-------
59
9. Storage and Disposal Statements
All products must have the appropriate storage and
disposal statements on the label. Refer to Appendix IV-4 for
the appropriate statements.
-------
60
V. PRODUCTS SUBJECT TO THIS STANDARD
All products containing one or more of the pesticides
identified in Section II.A. are subject to certain requirements
for data submission or changes in composition, labeling or
packaging of the product. The applicable requirements depend
on whether the product is a manufacturing or end use product
and whether the pesticide is the sole active ingredient or
one of multiple active ingredients.
Products are subject to this Registration Standard as
follows:
A. Manufacturing use products containing this pesticide as
the sole active ingredient are subject to:
1. The restrictions (if any) upon use, composition, or
packaging listed in Section IV, if they pertain to the
manufacturing use product. / ,
2. The data requirements listed in Tables A and B
3. The labeling requirements specified for manufacturing
use products in Section IV.
4. Administrative requirements (application forms, Confiden-
tial Statement of Formula, data compensation provisions)
associated with reregistration.
Data requirements are listed in the three Tables in
Appendix I of this Registration Standard. The Guide to
Tables in that Appendix explains how to read the Tables.
s
Table A lists generic data requirements applicable to all
products containing the pesticide subject to this Registra-
tion Standard. Table B lists product-specific data applicable
to manufacturing use products. The data in Tables A and B
need not be submitted by a producer who is eligible for the
formulator's exemption for that active ingredient.
Table C lists product-specific data applicable to end use
products. The Agency has decided that, in most cases, it
will not require the submission of product-specific data for
end use products at this time. Therefore most Registration
Standards do not contain a Table C.
-------
61
B. Manufacturing use products containing this pesticide
as one of multiple active ingredients are subject to:
The data requirements listed in Table A.
C. End use products containing this pesticide as the
sole active ingredient are subject to:
1. The restrictions (if any) upon use, composition, or
packaging listed in Section IV if they pertain to the
end use product.
2. If eligible for the formulator's exemption3, the
data requirements listed in Table C,
3. If not eligible for the formulator's exemption, the
data requirements listed in Table A and the data require-
ments listed in Table C.
4. The labeling requirements specified for end use
products in Section IV.
D. End use products containing this pesticide as one of
multiple active ingredients are subject to:
a. If not eligible for the formulator's exemption,
the data requirements listed in Tables A and C.
b. If eligible for the formulator's exemption, the
data requirements listed in Table C.
If you purchase from another producer and use as the
source of your active ingredient only EPA-registered products,
you are eligible for the formulator's exemption for generic
data concerning that active ingredient (Table A) and product-
specific data for the registered manufacturing use product
you purchase (Table B).
Two circumstances nullify this exemption:
1) If you change sources of active ingredient to an
unregistered product, formulate your own active ingredient,
or acquire your active ingredient from a firm with ownership
in common with yours, you individually lose the exemption
and become subject to the data requirements in Table A.
2) If no producer subject to the generic data requirements
in Table A agrees to submit the required data, all end use
producers lose the exemption, and become subject to those
data requirements.
-------
62
VI. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
This portion of the Registration Standard is a notice
issued under the authority of FIFRA sec. 3(c)(2)(B). It
refers to the data listed in Table A, which are required to
be submitted by registrants to maintain in effect the regis-
tration of products containing this active ingredient.4
A. What are generic data?
Generic data pertain to the properties or effects of a
particular active ingredient. Such data are relevant to an
evaluation of all products containing that active ingredient
regardless of whether the product contains other ingredients.
(unless the product bears labeling that would make the data
requirement inapplicable).
Generic data may also be data on a "typical formulation"
of a product. "Typical formulation" testing is often required
for ecological effects studies and applies to all products
having that formulation type. These are classed as generic
data, and are contained in Table A.
B. Who must submit generic data?
All current registrants are responsible for submitting
generic data in response to a data request under FI-FRA sec.
3(c)(2)(B) (DCI Notice). EPA has decided, however, not to
require a registrant who qualifies for the formulator's
exemption (FIFRA sec. 3(c)(2)(D) and § 152.85) to submit
generic data in response to a DCI notice if the registrant
who supplies the active ingredient in his product is complying
with the data request.
If you are not now eligible for a formulator's exemption,
you may qualify for one if you change your source of .supply
to a registered source that does not share ownership in
common with your firm. If you choose to change sources of
supply, the Confidential Statement of Formula must identify
the new source (s) and you must submit a Formula tor's Exemption
Statement
If you apply for a new registration for products containing
this active ingredient after the issuance of this Registration
Standard, you will be required to submit or cite generic
data relevant to the uses of your product if, at the time
4 Registrations granted after issuance of this Standard
will be conditioned upon submission or citation of the data
listed in this Registration Standard.
-------
63
the application is submitted, the data have been submitted
to the Agency by current registrants. If the required data
have not yet been submitted, any new registration will be
conditioned upon the new registrant's submission or citation
of the required data not later than the date upon which
current registrants of similar products are required to provide
such data. See FIFRA sec. 3(c)(7)(A). If you thereafter fail
to comply with the condition of that registration to provide
data, the registration may be cancelled (FIFRA sec. 6(e)).
C. What generic data must be submitted?
You may determine which generic data you must submit by
consulting Table A. That table lists the generic data needed
to evaluate current uses of all products containing this
active ingredient, the uses for which such data are required,
and the dates by which the data must be submitted to the
Agency.
D. How to comply with PCI requirements.
Within 90 days of your receipt of this Registration
Standard, you must submit to EPA a completed copy of the form
entitled "FIFRA Section 3(c)(2)(B) Summary Sheet" (EPA Form
8580-1, enclosed) for each of your products. On that form
you must state which of the following six methods you will
use to comply with the DCI requirements:
1. You will submit the data yourself.
2. You have entered into an agreement with one or more
registrants to ]Ointly develop (or share in the cost of
developing) the data, but will not be submitting the "data
yourself. If you use this method, you must state who will
submit the data on which you will rely. You must also provide
EPA with documentary evidence that an agreement has been
formed which allows you to rely upon the data to be submitted.
Such evidence may be: (1) your letter offering to join in
an agreement and the other registrant's acceptance of your
offer, (2) a written statement by the parties that an agreement
exists, or (3) a written statement by the person who will be
submitting the data that you may rely upon its submission.
The Agency will also require adequate assurance that the
person whom you state will provide the data is taking appropriate
steps to secure it. The agreement to produce the data need
not specify all of the terms of the final arrangement between
the parties or a mechanism to resolve the terms.
-------
64
3. You have attempted to enter into an agreement to
jointly develop data, but no other registrant has accepted
your offer. You request that EPA not suspend your registration
for non-compliance with the PCI.EPA has determined that,
as a general policy/it will not suspend the registration of
a product when the registrant has in good faith sought and
continues to seek to enter into a data development/cost
sharing program, but the other registrants developing the
data have refused to accept its offer. [If your offer is
accepted, you may qualify for Option 2 above by entering
into an agreement to supply the data.]
In order to qualify for this method, you must:
1. File with EPA a completed "Certification of Attempt
to Enter into an Agreement with other Registrants for Develop-
ment of Data" (EPA Form 8580-6, enclosed).
2. Provide us with a copy of your offer to the other
registrant and proof of the other registrant's receipt ot your
offer (such as a certified mail receipt). Your offer must,
at a minimum, contain the following language or its equivalent:
[Your company name] offers to share in the burden of
producing the data required pursuant to FIFRA sec.
3(c)(2)(B) in the [name of active ingredient] Registration
Standard upon terms to be agreed or failing agreement
to be tound by binding arbitration as provided by FIFRA
section 3(c)(2)(B)(in).
The remainder of your offer may not in any way attempt to
limit this commitment. It the other registrant to whom your
offer is made does not accept your offer, and if the other
registrant informs us on a DCI Summary Sheet that he will
develop and submit the data required under the DCI, then you
may qualify for this option. In order for you to avoid
suspension under this method, you may not later withdraw or
limit your offer to share in the burden of developing the
data. In addition, the other registrant must fulfill its
commitment to develop and submit the data.
4. You request a waiver of the data requirement. If
you believe that a data requirement does not (or should not)
apply to your product or its uses, you must provide EPA with
a statement of the reasons why you believe this is so. Your
statement must address the specific composition or use factors
that lead you to believe that a requirement does not apply.
Since the Agency has carefully considered the composition and
uses of pesticide products in determining that a data require-
ment applies, EPA does not anticipate that many waivers will
be granted. A request for waiver does not extend the time-
frames for developing required data, and if your waiver
request is denied, your registration may be suspended if you
fail to submit the data.
-------
65
5. You request that EPA amend your registration by deleting
the uses for vhich the data are needed. You are not required
to submit data for uses which are no longer on your label.
6. You request voluntary cancellation of the registration
of your product(s) for which the data are needed.
E. Procedures for reguesting a change in testing protocol.
It you will generate the required data and plan to use
test procedures which deviate from (or are not specified in)
either EPA's Pesticide Assessment Guidelines or the Reports
of Expert Groups to the Chemicals Group, Organization for
Economic Cooperation and Development (OECD) Chemicals Testing
Programme, you must submit for EPA approval the protocols
you propose to use.
You should submit your protocols before beginning testing
and await EPA approval, because the Agency will not ordinarily
accept as sufficient studies using unapproved protocols.
A request for protocol approval will not extend the timeframe
for submission of the data, nor will extensions generally be
given to conduct studies due to submittal of inappropriate
protocols.
F. Procedures for requesting extensions of time.
If you think that you will need more time to generate
the data than is allowed by EPA's schedule, you may submit a
request for an extension of time. Any request for a time
extension which is made as an initial response to a section
3(c)(2)(B) request notice must be submitted in writing to
the Product Manager listed at the end of this section and
must be made before the deadline for response. Once dates
have been committed to and EPA has accepted these commitments,
any subsequent requests for a time extension must be submitted
in writing to the Office of Compliance Monitoring.
EPA will view failure to request an extension before
the response deadline as a waiver of any future claim that
there was insufficient time to submit the data. While EPA
considers your request, you must strive to meet the deadline
for submitting the data.
The extension request should state the reasons why you
believe that an extension is necessary and the steps you
have taken to meet the testing deadline. Time extensions
normally will not be granted due to problems with laboratory
capacity or adequacy of funding, since the Agency believes
that with proper planning these can be overcome. Time extensions
may be considered when joint data development is planned,
-------
66
or when the Agency must approve a new or modified protocol
before the study can be begun.
A request for an extension does not extend the timeframe
for submission of the data. If EPA denies your request for
a time extension and you do not submit the data as requested/
EPA may begin proceedings to suspend the registrations of
your products.
G. Existing stocks provision upon suspension or cancellation.
The Agency has determined that if a registration is
suspended for failure to respond to a DCI request under
FIFRA sec. 3fc)(2)(B), an existing stocks provision is not
consistent with the Act. Accordingly, the Agency does not
anticipate granting permission to sell or distribute existing
stocks of suspended product except in rare circumstances.
If you believe that your product will be suspended or cancelled
and that an existing stocks provision should be granted/ you
have the burden of clearly demonstrating to EPA that granting
such permission would be consistent with the Act. The following
information must be included in any request for an existing
stocks provision:
• 1. Explanation of why an existing stocks provision is
necessary, including a statement of the quantity of
existing stocks and your estimate of the time required
for their sale or distribution; and
2. Demonstration that such a provision would be consis-
tent with the provisions of FIFRA.
-------
67
VII. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Under it-s DCI authority, EPA has determined that certain
product-specific data are required to maintain your registrations
in effect. Product-specific data are derived from testing
using a specific formulated product/ and, unlike generic
data, generally support only the registration of that product.
All such data must be submitted by the dates specified in
this Registration Standard.
If you have a manufacturing use product, these data are
listed in Table B. If you have an end use product, the data
are listed in Table C. As noted earlier, the Agency has
decided that it will not routinely require product-specific
data for end use products at this time. Therefore, Table C
may not be contained in this Registration Standard; if there
is no Table C/ you are not required to submit the data at
this time.
In order to comply with the product specific data require-
ments, you must follow the same procedures as for generic data.
See Section IV.D, E, F, and G. You should note, however, that
product chemistry data are required for every product, and the
only acceptable responses are options IV.D.I. (submit data)
or IV.D.6.(cancellation of registration).
Failure to comply with the product-specific data require-
ments for your products will result in suspension of the
product's registration.
-------
68
VIII. REQUIREMENT FOR SUBMISSION OF REVISED LABELING
FIFRA requires each product to be labeled with accurate,
complete and sufficient instructions and precautions, reflecting
the Agency's assessment of the data supporting the product
and its uses. General labeling requirements are set out in
40 CFR 162.10 (see Appendix II - LABELING and SUMMARY). In
addition, labeling requirements specific to products containing
this pesticide are specified in Section IV.D of this Registra-
tion Standard. Applications submitted in response to this
notice must include draft labeling for Agency review.
If you fail to submit revised labeling as required,
which complies with 40 CFR 162.10 and the specific instructions
in Section IV.D., EPA may seek to cancel or suspend the
registration of your product under FIFRA sec. 6.
-------
69
IX. INSTRUCTIONS FOR SUBMISSION
A. Manufacturing Use Products (MUPs) containing Methyl
Parathion as sole active ingredient.
1. Within 90 days from receipt of this document, you
must submit to the Product Manager in the Registration Division
for each product subject to this Registration Standard:
a. The "FIFRA Section 3(c)(2)(B) Summary Sheet" (EPA
Form 8580-1), with appropriate attachments.5
b. Confidential Statement of Formula (EPA Form 8570-4).
c. Formulator's Exemption Statement (EPA Form ),
if applicable.
d. Evidence of compliance with data compensation
requirements of FIFRA s"ec. 3(c)(l)(D). Refer to 40 CFR
152.80-152.99.
2. Within 9 months from receipt of this document you
must submit to the Product Manager:
a. Application for Pesticide Registration (EPA
Form 8570-1).
b. Two copies of any required product-specific data
(See Table B).
c. Three copies of draft labeling, including the
container label and any associated supplemental labeling.
Labeling should be either typewritten text on 8-1/2 x 11
inch paper or a raockup of the labeling suitable for
storage in 8-1/2 x 11 files. The draft label must indicate
the intended colors of the final label, clear indication
of the front panel of the label, and the intended"type
sizes of the text.
d. Product Specific Data Report (EPA Form 8580-4).
5 If on the Summary Sheet, you commit to develop the data,
present arguments that a data requirement is not applicable
or should be waived, or submit protocols or modified protocols
for Agency review, you must submit a copy of the Summary
Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data
generated in response to this notice. This submission is in
addition to responding to the Product Manager, and should be
submitted to the Office of Compliance Monitoring at the
address given at the end of this section. (Actual studies
are not to be submitted to the Office of Compliance Monitoring.)
-------
70
3. Within the times set forth in Table A, you must
submit to the Registration Division all generic data, unless
you are eligible for the formulator's exemption. If for any
reason any test is delayed or aborted so that the schedule
cannot be met, immediately notify the Product Manager and
the Office of Compliance Monitoring of the problem, the
reasons for the problem, and your proposed course of action.
B. Manufacturing Use Products containing Methyl Parathion
in combination with other active ingredients.
1. Within 90 days from receipt of this document, you
must submit to the Product Manager in the Registration Division:
a. FIFRA sec. 3(c)(2)(B) Summary Sheet, with appropriate
attachments5 (EPA Form 8580-1).
b. Confidential Statement of Formula (EPA Form 8570-4)
c. Formulator's Exemption Statement if applicable.
2. Within the time frames set forth in Table A, you must
submit to the Registration Division all generic data, unless
you are eligible for the formulator's exemption. If for any
reason any test is delayed or aborted so that the schedule
cannot be met, immediately notify the Product Manager and
the Office of Compliance Monitoring of the problem, the
reasons for the problem, and your proposed course of action.
C. End Use Products containing Methyl Parathion as sole
active ingredient.
1. Within 90 days from receipt of this document, you
must submit to the Product Manager in the Registration Division:
a. FIFRA Section 3(c)(2)(B) Summary Sheet, with
appropriate attachments5 (EPA Form 8580-1).
b. Confidential Statement of Formula (EPA Form 857U-4).
c. Formulator's Exemption Statement if applicable.
2. Within 9 months from receipt of this document you
must submit to the Product Manager:
a. Two copies of any product-specific data, if required
by Table C.
b. Product Specific Data Report (EPA Form 8580-4),
if Table C lists required product-specific data.
-------
71
c. Three copies of draft labeling, including the container
label and any .associated supplemental labeling. Labeling should
be either typewritten text on 8-1/2 x 11 inch paper or a mockup
of the labeling suitable for storage in 8-1/2 x 11 files. The
draft labeling must indicate the intended colors of the final
label, clear indication of the front panel of the label, and
the intended type sizes of the text. End use product labeling
must comply specifically with the instructions in Section IV
(Regulatory Position and Rationale).
D. Intrastate Products containing Methyl Parathion either
as sole active ingredient or in combination with other
active ingredients.
These products are being called in for full Federal regis-
tration. Producers of these products are being sent a letter
instructing them how to submit an application for registration.
E. Addresses
The required information must be submitted to the following
address:
Dennis Edwards (PM-12)
Registration Division (TS-767C)
Office of Pesticide Programs
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460
The address for submissions to the Office of Compliance
Monitoring is:
Laboratory Data Integrity Program
Office of Compliance Monitoring (EN-342)
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460.
-------
72
ATTACHMENT I
METHYL PARATHION (LABELING INFORMATION FOR RANGE AND PASTURELAND)
ENDANGERED SPECIES RESTRICTIONS
The use of any pesticide in a manner that may kill or otherwise harm an
endangered or threatened species or adversely modify their habitat is a
violation of federal laws. The use of this product is controlled to prevent
death or harm to endangered or threatened species that occur in the following
counties or elsewhere in their range.
Before using this pesticide in these counties you must obtain the EPA Rangeland
Endangered Species Bulletin. The use of this pesticide is prohibited in the
below named counties unless specified otherwise in the Bulletin. The Rangeland
Bulletin is available from either your County Agricultural Extension Agent, the
Endangered Species Specialist in your State Wildlife Agency Headquarters or the
appropriate Regional Office of either the U.S. Fish and Wildlife Service or the
U.S. Environmental Protection Agency. THIS BULLETIN MUST BE REVIEWED PRIOR
TO PESTICIDE USE.
STATE (Regional Office FWS/EPA)
Species COUNTY (unless specified otherwise)
ARIZONA (Albuquerque, N.M./San Francisco, CA.)
Masked bobwhite Puna, Santa Cruz
CALIFORNIA (Portland, OR./San Francisco, CA.)
Santa Cruz long-toed salamander Santa Cruz, Monterey
Delta green ground beetle Solano
Valley elderberry longhom beetle Merced
Kern primrose sphinx moth Kern
Aleutian Canada goose Colusa, Merced, San Joaquin, Stanislaus
California condor Monterey, San Benito, San Luis Obispo,
Kings, Tulare, Kern, Santa Barbara,
Ventura, Los Angeles, Fresno
Blunt-nosed leopard lizard Kern, Kings, Fresno, Madera, Merced,
Monterey, San Luis Obispo, Santa
Barbara, Stanislaus, Tulare
FLORIDA (Atlanta, GA.)
Eastern indigo snake Statewide
-------
73
STATE (Regional Office FVB/EPA)
Species
County (unless specified statewide)
GEORGIA (Atlanta, GA.)
Eastern indigo snake
HAWAII (Portland, OR./Seattle, WA.)
Hawaiian goose
IDAHO (Portland, OR./Seattle, WA.)
Whooping crane
MISSISSIPPI (Atlanta, GA.)
Mississippi sandhill crane
NEW MEXICO (Albuquerque, N.M./Dallas, IX.)
Socorro isopod
New Mexican ridge-nosed rattlesnake
TEXAS (Albuquerque, N.M./Dallas, TX.)
San Marcos salamander
Houston toad
UTAH (Denver, CO.)
Desert tortoise
WYOMING (Denver, CO.)
Whooping crare
S.E. Georgia
Islands of Maui and Hawaii
Caribou, Bear Lake and Bonneville
Jackson
Socorro
Hidalgo
Hays
Bastrop, Burleson
Washington
Lincoln and Sublette
-------
74
[MEIHYL PARA1HION (LABELING INPORMATICN FOR MOSQUITO LARVICIDE USES)]
ENDANGERED SPECIES RESTRICTIONS
The use of any pesticide in a manner that may kill or otherwise ham an endangered
or threatened species or adversely modify their habitat is a violation of
federal laws. The use of this product is controlled to prevent death or harm
to endangered or threatened species that occur in the following counties or
elsewhere in their range:
Before using this pesticide in the following counties you must first contact the
Endangered Species Specialist in the appropriate Regional/Field Office of the U.S.
Fish and Wildlife Service (FWS) indicated below. Specific information describing
the locations of areas to be treated must be provided to FVB. use of this product
in the range of endangered species, as described by FWS, is prohibited.
Contact FWS Field Offices at the following numbers;
ARIZONA (Phoenix, AR, 602-241-2493)
Yuma clapper rail Mohave and Yuma
CALIFORNIA (Sacramento, CA, 916-978-4613)
Aleutian Canada goose Colusa, Merced, Stanislaus and Sutter
Salt Marsh harvest mouse Alameda, Contra Costra and Mann
Clapper rail Alameda, Contra Costra, Humbolt, Mann,
Monterey, Napa, Solano, San Luis Obispo,
San Mateo, Santa Clara and Sorcma
Yuma clapper rail Imperial, Riverside and San Bernardino
Light-footed clapper rail Orange, Los Angeles, San Diego,
Santa Barbara and Ventura
California least tern Alameda, Los Angeles, Orange, San Diego,
San Mateo, Santa Barbara and Ventura
DISTRICT OF COLUMBIA (Annapolis, MD, 301-269-5448)
Hay's Spring amphipod Rock Creek Park
HAWAII (Honolulu, HA, 808-546-5608)
Hawaiian gallinule Island of Oahu
Hawaiian coot Islands of Kauai, Maui, Molokai,
Hawaiian stilt Islands of Kauai, Maui, Nnhau and Oahu
IDAHO (Boise, ID, 208-334-1806)
Whooping crane Caribou, Bear Lake and Bonneville
-------
75
KENTUCKY (Asheville, NC, 704-259-0321)
Kentucky Cave shrimp Edmundson and Hart
MISSISSIPPI (Jackson, MS, 601-960-4900)
Mississippi sandhill crane Jackson
NEW MEXICO (Albuquerque, MM, 505-566-2323)
Socorro isopod Socorro
VIRGINIA (Annapolis, MD, 301-269-5448)
Madison Cave isopod Augusta
WOMING (Helena, MT, 406-449-5225)
Whooping crane Lincoln and Sublette
-------
76
[METHYL PARATHICN LABEL INFORMATION (CPOP USES)
ENDANGERED SPECIES RESTRICTIONS
The use of any pesticide in a manner that may kill or otherwise haon an
endangered or threatened species or adversely modify their habitat is a
violation of federal laws. The use of this product is controlled to prevent
death or harm to endangered or threatened species that occur in the following
counties or elsewhere in their range.
Before using this pesticide in the following counties you must obtain the EPA
Cropland Endangered Species Bulletin. The use of this pesticide is prohibited in
these counties unless specified otherwise in the Bulletins. The EPA Bulletin is
available from either your County Agricultural Extension Agent, the Endangered
Species Specialist in your State Wildlife Agency Headquarters or the appropriate
Regional Office of either the U.S. Fish and Wildlife Service (FWS) or the
U.S. Environmental Protection Agency. THIS BULLETIN MUST BE REVIEWED PRIOR
TO PESTICIDE USE.
STATE (Regional Office FWS)
Species
CALIFORNIA (Portland, OR.)
Aleutian Canada goose
Blunt-nosed leopard lizard
Delta green ground beetle
Kern primrose sphinx moth
Santa Cruz long-toed
salamander
Valley elderberry
longhorn beetle
FLORIDA (Atlanta, GA.)
Everglade kite
TEXAS (Albuquerque, N.M.)
Attwater's greater
prairie chicken
Houston toad
San Marcos salamander
Texas blind salamander
COUNT*
COLUSA
MERCED
FRESNO
KERN
KINGS
MADERA
MERCED
SUITER
STANISLAUS
MONTEREY
SAN LUIS OBISPO
SANTA BARBARA
STANISLAUS
TULARE
SOLANO
KERN
MONTEREY
SANTA CRUZ
MERCED
SACRAMENTO
DADE
GLADES
ARANSAS
AUSTIN
COLORADO
FORT BEND
BASTROP
PALM BEACH
BROWARD
GOLIAD
REFUGIO
VICTORIA
BURLESON
HAYS
HAYS
-------
77
[METHYL PARA1HICN LABEL INFORMATION (FOREST USES)
ENDANGERED SPECIES RESTRICTIONS
The use of any pesticide in a manner that may kill or otherwise harm an
endangered or threatened species or adversely modify their habitat is a
violation of federal laws. The use of this product is controlled to prevent
death or harm to endangered or threatened species that occur in the following
counties or elsewhere in their range.
Before using this pesticide in the following counties you must first contact the
Endangered Species Specialist in the appropriate Regional/Field Office of the U.S.
Fish and Wildlife Service (FWS) indicated below. Specific information describing
the locations of areas to be treated must be provided to FWS. Use of this product
in the range of endangered species, as described by FWS, is prohibited.
Contact FWS Field Offices at the following numbers;
ALABAMA (Jackson, MS, 601-960-4900)
Red-cockaded woodpecker Baldwin, Bibb, Calhoun, Chilton, Clay
Cleburne, Covington, Escambia, Dale,
Jefferson, Lawrence, Macon, Perry, Shelby,
St. Clair, Talladega, Tuscalcosa and Winston
ARKANSAS (Jackson, MS, 601-960-4900)
Red-cockaded woodpecker Ashley, Calhoun, Clark, Columbia, Hempstead,
Lafayette, Monroe, Ouachita, Polk, Scott
and Union
FLORIDA (Jacksonville, FL, 904-791-2580)
Red-cockaded woodpecker Alachua, Baker, Bay, Brevard, Charlotte,
Citrus, Clay, Columbia, Duval, Franklin,
Glades, Gulf, Hernando, Highlands, Lee, Leon,
Levy, Liberty, Marion, Martin, Okaloosa,
Okeechobee, Osceola, Palm Beach, Pasco,
St. Johns, Santa Rosa, Wakulla and Walton
GEORGIA (Jacksonville, FL, 904-791-2580)
Red-cockaded woodpecker Appling, Baldwin, Brantley, Charlton,
Chattahoochee, Clarke, Clinch, Decatur, Floyd,
Glynn, Grady, Harris, Jasper, Jenkins, Jones,
Pierce, Putnam, Screven, Tattnall, Telfair,
Thomas, Tocmbs, Turner, Ware, Washington
and Wilkes
KENTUCKY (Asheville, NC, 704-259-0321)
Red-cockaded woodpecker Laurel and McCreary
-------
78
LOUISIANA (Jackson, MS, 601-960-4900)
Red-cockaded woodpecker Allen, Beauregard, Bienville, Bossier, Caddo,
Calcasieu, Catahoula, Claiborne, Grant,
La Salle, Morehouse, Natchitoches, Ouachita,
Rapides, St. Tamnany, Tangipahoa, Union,
Vemon and Washington
MARYLAND (Anrapolis, MD, 301-269-5448)
Red-cockaded woodpecker Dorchester
MICHIGAN (E. Lansing, MI, 517-337-6650)
Kirtland's warbler Crawford, Kalkaska, Oscoda, Ogernaw,
Roscarmon and Wexford
MISSISSIPPI (Jackson, MS, 601-960-4900)
Red-cockaded woodpecker Choctaw, Copiah, Franklin, Harrison, Hinds,
Jackson, Jones, Lauderdale, Leake, Madison,
Marion, Noxubee, Oktibbeha, Pearl River,
Scott, Smith, Stone, Wayne, Wilkinson and
Winston
NORTH CAROLINA (Asheville, NC, 704-259-0321)
Red-cockaded woodpecker Beaufort, Bertie, Bladen, Brunswick,
Cumberland, Gates, Harnett, Hertford, Hoke,
Hyde, Jones, Montgomery, Moore, Northampton,
v Onslow, Pamlico, Perquimans, Pitt, Richmond,
Wake and Wayne
OKLAHOMA (Tulsa, OK, 918-581-7458)
Red-cockaded woodpecker Bryan, Latimer, Le Flore, McCurtain, Pittsburg
and Pushmataha
SOUTH CAROLINA (Asheville, NC, 704-259-0321)
Red-cockaded woodpecker Aiken, Barnwell, Beaufort, Berkeley, Calhoun,
Charleston, Chesterfield, Clarerdon, Colleton,
Darlington, Dillon, Dorchester, Edgefield,
Florence, Georgetown, Hampton, Horry, Laurens,
Lee, Lexington, Orangeburgr Richland, Sumter
and Williamsburg
TENNESSEE (Asheville, NC, 704-259-0321)
Red-cockaded woodpecker Blount, Campbell, Cumberland and Morgan
TEXAS (Houston, TX, 713-229-3681)
Red-cockaded woodpecker Angelina, Cass, Cherokee, Hardin, Houston,
Jasper, Montgomery, Nacogdoches, Newton,
Polk, Sabine, San Augustine, San Jacinto,
Shelby, Trinity, Tyler and Walker
VIRGINIA (Annapolis, MD, 301-269-5448)
Red-cockaded woodpecker Prince George, Southampton, Surry and
Sussex
-------
79
TGUIDE-l
GTTTTiT? T*n
Tables A, B, and C contain listings of data requirements
for the pesticides covered by this Registration Standard.
Table A contains generic data requirements that apply to
the pesticide in all products, including data requirements
for which a "typical formulation" is the test substance.
Table B contains product-specific data requirements that
apply only to a manufacturing use product.
Table C contains product-specific data requirements that
apply only to an end use product.
The data tables are generally organized according to the
following format:
1. Data Requirement (Column 1). The data requirements are
listed in the order in which they appear in 40 CFR Part 158.
The reference numbers accompanying each test refer to the
test protocols set out in the Pesticide Assessment Guidelines,
which are available from the National Technical Information
Service, 5285 Port Royal Road, Springfield, VA 22161.
2. Test Substance (Column 2). This column lists the composition
of the test substance required to be used for the test, as
follows:
/
TGAI - Technical grade of the active ingredient
PAI » Pure active ingredient
PAIRA = Pure active ingredient, radio labeled
TEP » Typical end use formulation
MP « Manufacturing use product
EP - End use product
Any other test substances, such as metabolites, will be
specifically named in Column 2 or in footnotes to the table.
3. Use pattern (Column 3). This column indicates the use
patterns to which the data requirement applies. Use patterns
are the same as those given in 40 CFR Part 158. The following
letter designations are used for the given use patterns:
A » Terrestrial, food
B =» Terrestrial, non-food
C = Aquatic, food
D » Aquatic, non-food
E » Greenhouse, food
F * Greenhouse, non-food
G « Forestry
H = Domestic outdoor
I « Indoor
Any other designations will be defined in a footnote to the table.
-------
80
TGUIDE-2
4. Does EPA have data? (Column 4). This column indicates one
of three answers:
YES - EPA has data in its files that completely satisfy
this data requirement. These data may be cited by
other registrants in accordance with data compensation
requirements of Part 152, Subpart E.
PARTIALLY - EPA has some data in its files, but such data
do not fully satisfy the data requirement. In some cases,
the Agency may possess data on one of two required species,
or may possess data on one test substance but not all.
The term may also indicate that the data available to
EPA are incomplete. In this case, when the data are
clarified, or additional details of the testing submitted
by the original data submitter, the data may be determined
to be acceptable. If this is the case, a footnote to
the table will usually say so.
NJ3 - EPA either possesses no data which are sufficient
to fulfill the data requirement, or the data which EPA
does possess are flawed scientifically in a manner that
cannot be remedied by clarification or additional infor-
mation.
5. Bibliographic citation (Column 5). If the Agency has
acceptable data in its files, this column lists the identifying
number of each study. This normally is the Master Record
Identification (MRID) number, but may be a GS number if no
MRID number has been assigned. Refer to the Bibliography
Appendices for a complete citation of the study.
6. Must additional data be submitted? (Column 6). This
column indicates whether the data must be submitted to the
Agency. If column 3 indicates that the Agency already has
data, this column will usually indicate NO. If column 3
indicates that the Agency has only partial data or no data,
this column will usually indicate YES. In some cases, even
though the Agency does not have the data, EPA will not require
its submission because of the unique characteristics of the
chemical; because data on another chemical can be used to
fulfill the data requirement; or because the data requirement
has been waived or reserved. Any such unusual situations
will be explained in a footnote to the table.
7. Timeframe for submission (Column 7). If column 5 requires
that data be submitted, this column indicates when the data
are to be submitted, based on the issuance date of the Regis-
tration Standard. The timeframes are those established either
as a result of a previous Data Call-in letter, or standardized
timeframes established by PR Notice 85-5 (August 22, 1985) .
8. Footnotes (at the end of each table). Self-explanatory.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Guideline Citation and
Name of Test
Test Guidelines
Substance!/ Status
Are Data
Required?
Yes No
§158.120 Product Chemistry
Product Identity;
61-2 - Description of Beginning TGAI
Materials and Manufacturing
Process
61-3 - Discussion of Formation of TGAI
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis TGAI
Physical and Chemical Characteristics
R
[XI
IX)
CR
IX)
I 1
Data Must Be
Submitted Within
Time frames Listed
Below2/
6 Months
6 Months
12 Months
63-2
63-3
63-4
63-5
63-6
• *
- Color
- Physical State
- Odor
- Melting Point
- Boiling Point
TGAI
TGAI
TGAI
TGAI
1GAI
R
R
R
R
R
• ••••**•<
(XI
ixi
1X1
(XI
HI
[_]
o
o
n
n
6 Months
6 Months
6 Months
6 Months
6 Months
CO
-------
TABLE A
GENERIC DATA REQUIREMENTS pQR METHYL PARATHION
Guideline Citation and
Name of Test
Test Guidelines Are Data
Substance^/ Status Required?
Yes No
Data Must Be
Submitted Within
Time frames Listed
Below2/
§158.120 Product Chemistry (continued)
Physical and Chemical Characteristics (continued)
63-7
63-8
63-9
63-10
63-11
63-12
63-13
Other
- Density, Bulk Density, or
Specific Gravity
- Solubility
- Vapor Pressure
- Dissociation constant
- Octanol/water partition
coefficient
- PH
- Stability
Requirements:
TGAI
TGAI or PAI
PAI
pXi
PAI
TGAI
TGAI
R
R
R
R
R
R
R
IX)
IX)
IX)
IX)
IX)
IX)
IX]
IJ
IJ
IJ
IJ
IJ
IJ
IJ
6
6
6
6
6
6
6
Months
Months
Months
Months
Months
Months
Months
CO
64-1 - Submittal of samples
TGAI, PAI
CR
IJ
IX)
I/ TGAI = Technical Grade of the Active Ingredient; PAI = Pure Active Ingredient; R = Required;
CR = Conditionally Required.
2/ Data must be submitted within the indicated time frames, which begin on the date of the Guidance Document
(see front cover for this date).
-------
TABLE A
GENERIC DATA REQUIREMENTS POR METHYL PARATHION
Data Requirements
Compositlon^/
Does EPA Have Data
To Satisfy This
Requicement? (Yes,
No, or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Tuneframes For Data
Sutinission2/
§158.125 Residue Chemistry
171-3 - Directions for Use
171-4 - Nature of Residue (Metabolism)
- Plants
- Livestock
171-4 - Residue Analytical Method
- plant residues
- Animal residues
171-4 - Storage Stability Data
171-4 - Magnitude of the Residue-
Residue Studies for each
Food use
- Root and Tuber Vegetables
Gioup
PAIRA
PAIRA and Plant
Metabolites
TGAI and
Metabolites
TGAI and
Metabolites
>
PAI
TEP
Yes
Partially
Partially
Yes
Yes
Partially
Partially
GS00153004
GS00153001
00128039
00003724,
00073196
00085260,
00085262,
00101122,
00101213,
00102367,
00102414,
05004211
00035330
00080018
00085261
00101100
00101124
00102312
00102376
00112173
00047726, 00105217
00102314
00101095, 00102356
00102418, 00031669
No
YesV IB Months
YesV 18 Months
NoV
NoV
Yes^X 18 Months
YesV is Months
CO
-------
GENERIC DATA REQUIREMEWHT FDR METHYL PARATHICN
Data Requirement
CompositionV
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Must Additional Data
Be Submitted Under
Bibliographic FIFRA § 3(c)(2)(B)?
Citation Timeframes for Data
Submission2/
§158.125 Residue Chemistry (continued)
171-4 - Magnitude of the Residue -
Residue Studies (continued)
- Leaves of Root and Tuber
Vegetables Group
- Bulb Vegetables Group
- Leafy Vegetables Group
- Brassica Leafy Vegetables
Group
- Legume Vegetables Group
Foliage of Legume Vegetables
Group
Fruiting Vegetables Group
(Except Cucurbits)
Cucurbit Vegetables Group
Pome Fruits Group
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
Partially
Partially
No
Partially
Partially
Partially
Partially
No
Partially
00101095, 00102418 Yes8 / 18 Months
00102356
00061199, 00102356
00009821, 00009822
00031669, 00102417
00102370, 001379B6
GS00153002, 00101100
00102314, 00102367
00072376, 00102417
00102314, 00101100
00102367, 00102356
00102418, 00102292
00102415, 00102417
00102356
00047726, 00051649
00086695, 00102355
YesV 18 Months
YesW 18 Months
YesW 18 Months
Yes12/ 18 Months
18 Months
YesH/ 18 Months
Yes^V 18 Months
Yes16/ 18 Months
CO
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Data Requirement
Compositionl/
Does EPA Have Data
To Satisfy This
Requi rement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA § 3(C)(2)(B)7
Time frames for Data
Submission2/
§158.125 Residue Chemistry (continued)
174-4 - Magnitude of the Residue-
Residue studies (continued)
- Stone Fruits Group
- Small Fruits Group
- Tree Nut Group
- Cereal Grains Group
Forage, Fodder, and Straw
of Cereal Grains Group
Grass Forage, Fodder, and
Hay Group
Non-Grass Animal Feeds
(Forage, Fodder, Straw,
and Hay) Group
TEP
TEP
TEP
TEP
TEP
TEP
TEP
Partially
Partially
Partially
Partially
Partially
Partially
Partially
00102356, 00047726
00102417, 00102418
00102418, 00031669
00051649,
00086695,
00085260,
00101096,
00081419,
00101213
00072376
00085259
00085261
00053436
00101098
00051649, 00085261
00101096, 00053436
00081419, 00101098
00101213, 00072376
00102417
00035330, 00035332
00035890, 00047726
00072376, 00101221
00102356, 00104198
B Months
YesW 18 Months
Yes^V 18 Months
Yes20/ 18 Months
Yeg21/ 18
Yes22/ 18
Yes23/ IB Months
OO
(Jl
-------
TABLEA
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Data Requirement
Compositionl/
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliogtaphic
No or Partially) Citation
Must Additional Data
Be Submitted Under
FIFRA S 3(C)(2)(B)?
Time frames for Data
Submission2/
$158.125 Residue Chemistry (continued)
174-4 - Magnitude of the Residue-
Residue studies (continued)
- Miscellaneous Commodities
- Artichoke
- Cottonseed
- Hops
- Mustard Seed
- Peanuts
- Rapeseed
- Saf flower seed
- Sunflower seed
- Tobacco
TEP
TEP
TEP
TEP
TEP
TEP
' TEP
TEP
TEP
Partially
Partially
NO
Yes
Partially
Partially
No
Partially
Partially
00102415
00008516,
00086695,
00101100,
00101226,
00102291,
00102362,
00105217,
GSOO 153003,
-
00003724
00102418
00003724
-
00031669,
00102356
00080018
00099011
00101122
00101489
00102314
00102376
00113173
00153356
01012312
Yes24/ is Months
Yes25/ 18 Months
CO
ON
Yes^6/ 18 Months
No
Yes2?/ IB Months
Yes^8/ 18 Months
Yes2V 18 Months
YesW 18 Months
Yes 3 I/ is Months
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Does EPA Have Data Must Additional Data
To Satisfy This Be Submitted Under
Requirement? (Yes, Bibliographic FIFRA § 3(c)(2)(B)?
Data Requirement Composition^/ No or Partially) Citation Timeframes for Data
______ _ Submission2/ _
§158.125 Residue Chemistry (continued)
171-4 - Magnitude of the Residue TGAI or plant/ No Reserved32/
in Food-producing animals animal metabolites
meat, milk, poultry and eggs
171-6 - Proposed Tolerance Residue of No - Yes2V 18 Months
Concern
171-13 - Submittal of Analytical PAIRA ReservedW
Reference Standards
§158.125 Residue Chemistry (continued)
I/ Composition: TSAI =» Technical grade of the active ingredient, PAIRA = Pure active ingredient, radiolabelled;
TEP = Typical end-use product; EP = End-use product.
2/ Data must be submitted within the indicated time frames, which begin on the date of the Guidance Document
(see front cover for this date).
J/ Data are required reflecting the distribution and metabolism of ring-labeled 14C- methyl parathion in cotton-
seed and cotton forage following foliar treatments, in potato-tubers following foliar treatments, and in
lettuce following foliar treatments. If the metabolism of methyl parathion in these three crops differs sign-
ificantly, then metabolism data will be required for one representative commodity from each crop group for
which there are registered uses of methyl parathion.
_4/ Metabolism studies are required utilizing ruminants and poultry. Animals must be dosed for 3 days with
uniformly phenyl-labeled l*4Cl methyl parathion at a concentration in the total diet which will result in
sufficient residues in the tissues, milk, and eggs for characterization. Animals must be sacrificed within 24
hours of the final dose (milk and eggs must be collected twice daily). l^C-Residues must be characterized
fat, kidney, liver, milk, and eggs.
CO
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
5/ If additional metabolites of concern are detected in plants and/or if tolerances must be proposed for
residues in animal products, additional data may be required.
**.
6/ The storage intervals and conditions of storage of samples of raw agricultural commodities used to support the
established tolerances for residues of methyl parathion must be submitted. These data must be supported by
information depicting the percent decline in residues of methyl pa rath ion at the times and under the conditions
specified. All residue data requested in this standard must be accompanied by data regarding storage length
and conditions of storage of samples analyzed. These data must be accompanied by data depicting the stability
of residues under the conditions and for the time intervals specified. On receipt of the above data, the
adequacy of the aforementioned tolerances will be reevaluated.
7/ A group tolerance is not appropriate at the present time because methyl parathion use patterns on the
conrnodities in this group differ significantly in that the maximum registered rates difter up to a
factor of four. Tolerances for residues in or on sugar beets, potatoes, and sweet potatoes (0.1 ppm)
differ by more that a factor of five from the tolerances for residues in or on the remaining commodities
in this crop group (1 ppm). Additional data are required for residues in/on garden beet roots, carrots,
potato tubers, rutabagas roots, sugar beet roots, sweet potatoes, and turnip roots.
a. Data are required for methyl parathion residues of concern in or on garden beet roots as follows:
Depiction of residues of concern 21 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, a Dust (D) formulation at 0.63 Ib ai/A, a Wet table Powder (WP) formulation
a 1 Ib ai/A, and an Emulsifiable Concentrate (EC) formulation at 1 Ib ai/A. An analogous set of
tests must be conducted depicting residues of concern 15 days after application of 0.5 Ib ai/A of
of the D, WP, and EC formulations, in separate tests, applications prior to the last one should be
made at 7-day intervals at the respective maximum registered uses of 0.63, 1, and 1 Ib ai/A. Separ-
ate tests must be conducted iVi CA (including irrigated regions), NY, OR, TX, and WI.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar treatments; the data required above must reflect the proposed number.
b. Data for methyl parathion residues of concern in or on carrots are required as follows:
Depiction of residues of concern 15 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, a D, WP and EC formulation at 1 Ib ai/A/ application. Tests must be
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
conducted with both aerial and ground equipment in separate tests. Tests with EC and WP formulations
must include ULV applications. Tests must be conducted in CA (including irrigated regions), MI/ TX,
and MA.
A label restriction must be proposed which specifies the maximum number of applications allowed per
season; the data required above must reflect that number.
c. Data are required depicting methyl parathion residues of concern in or on potato tubers as follows:
Depiction of residues of concern 5 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, a EC and a WP formulation at 1.5 Ib ai/A. Separate tests must be con-
ducted with ground and ULV aerial equipment. Tests must be conducted in CA (including irrigated
regions), PL, ID, ME, and WI.
A label restriction must be posed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number.
Residues must be determined in granules, chips, and dried potatoes processed tram tubers bearing
measurable weathered residues. If residues are found to concentrate in any of these processed products,
appropriate food additive tolerances must be proposed.
d. Data depicting methyl parathion residues of concern on or in rutabagas roots are required as follows:
Depiction of residues of concern 21 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, EC and WP formulations at 1.5 Ib ai/A. Also, data must be submitted
depiciting residues in or on rutabaga roots harvested 7 days after the last ot two foliar applications
of an EC formulation at 0.5 Ib ai/A which were preceded by several foliar applications, a 7-day inter-
vals, at 1.5 Ib ai/A up to 21, days betore harvest. Both ground and ULV aerial equipment must be used,
in separate tests. Tests must be conducted in MM, WI, and WA.
A label restriction must be proposed which gives the maximum number of applications allowed per season
tor foliar treatments; the data required above must reflect the proposed number.
e. Data depicting methyl parathion residues of concern in or on sugar beet roots are required as follows.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
Depiction of residues of concern 20 days atter the last of several foliar applications at 7-day inter-
vals of, in separate tests, EC and WP formulations at 0.375 Ib ai/A. Both ground and ULV aerial
equipment must be used, in separate tests. Tests must be conducted in CA (including irrigated regions),
ID, MN, and ND.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar treatments; the data required above must reflect the proposed number.
Residues must be determined in dehydrated pulp, molasses, and refined sugar processed from roots bear-
ing measurable weathered residues. If residues are found to concentrate in any of these processed
products, appropriate food/feed additive tolerances must be proposed.
f. Data depicting methyl parathion residues of concern in or on sweet potatoes are required as follows:
Depiction of residues of concern 5 days atter the last of several toliar applications at 7-day inter-
vals using, in separate tests, an EC and a WP formulation at 0.8 Ib ai/A. Both ground and ULV aerial
treatments must be represented. Tests must be conducted in CA (including irrigated regions) and NC.
A label restriction must be prepared limiting the number of permissible foliar applications per season;
the data requested above must reflect that number.
g. Data are required depicting methyl parathion residues of concern in and on turnip roots as follows:
Depiction of residues of concern 15 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, EC and WP formulations at 0.8 Ib ai/A. Also, data must be submitted
depiciting residues in or on turnip roots harvested 7 days atter several foliar applications of an EC
and WP formulations, in separate tests, at 0.5 Ib ai/A (prior applications should be made at 7-day
intervals at the maximum rate). Both ground and ULV aerial equipment must be used, in separate tests.
Tests must be conducted in CA (including irrigated regions), GA, PA, TX, and WA.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number.
-------
TABLE A
GENERIC DATA REQUIREMENTS TOR METHYL PARATHICN
$158.125 Residue Chemistry (continued)
8/ A group tolerance is not appropriate at the present time because methyl parathion use patterns for the
commodities in this group differ significantly in that the maximum registered rates differ up to a factor
of tour. Tolerances for residues of methyl parathion in or on beet greens and turnip greens (1 ppm)
differ by more than a factor of five from the established tolerance for residues in or on sugar beet 'tops.
Additional data are required for garden beet tops, sugar beet tops and turnip greens.
a. Data are required depicting methyl parathion residues of concern in or on garden beet tops as follows:
Depiction of residues of concern 21 days after the last of several foliar applications at 7-day inter-
vals of/ in separate tests, a WP and EC formulations at 1 Ib ai/A. Both ground and ULV aerial equipment
must be used, in separate tests. Tests must be conducted in CA (including irrigated regions), NY, OR, TX,
and WI.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number.
b. Data are required depicting methyl parathion residues of concern in or on sugar beet tops as follows:
Depiction of residues of concern 60 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, a WP and EC formulation at 0.37b Ib ai/A. Separate tests must be conducted
with ground and ULV aerial applications. Tests must be conducted in CA (including irrigated regions),
ID, MM, and ND.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number.
c. Data are required depicting methyl parathion residues of concern in and on turnip tops as follows:
Depiction of residues of concern 21 days after the last of several foliar applications at 7-day inter-
vals of, in separate tests, a WP and EC formulation at 0.8 Ib ai/A. Residues must also be determined
7 days after the last of two foliar applications of an EC and a WP formulation, in separate tests,
at 0.5 Ib ai/A: these applications must be preceded by-several applications, up to 21 days before
harvest, made at 7-day intervals at the maximum rate (0.8 Ib ai/A). Tests must be conducted in CA
(including irrigated regions), GA, PA, TX, and WA.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
9/ A crop group tolerance is not appropriate at the present time because data must be submitted tor onions
(green and bulb) and one other commodity representative ot this crop group.
a. Data are required depicting methyl parathion residues of concern in and on onion bulbs and green'
onions as follows:
Residue data for green and bulb onions harvested 15 days after the last of several (applied at 7-day
intervals) ground and aerial foliar applications of, in separate tests, of an EC formulation at 1 Ib ai/A,
Ib ai/A. Testing must be conducted in CA, MI, NY, OH, or WA, and TX for bulb onions, and A2 or NM, CA
and NJ for green onions.
A label restriction must be proposed which gives the maximum number of applications allowed per season
for foliar applications; the data required above must reflect that number.
10/ A leaty vegetable crop group tolerance is~not appropriate at the present time because additional residue
data are required for celery, leaf and head lettuce, and spinach.
a. Data are required depicting methyl parathion residues ot concern in and on celery as follows:
Data depicting residues of concern in or on celery after multiple foliar applications by ground and
aerial equipment (in separate trials) at 7-day intervals are needed. Data are required tor repres -
sentative D, WP and EC formulations at 1.0 Ib ai/A applied in separate treatments and with side-by-
side formulation comparisons (EC versus D or WP in a given location) from several trials.
Samples must be collected 15 days after the last application. Geographic distribution must include
CA (central and southern coast locations) and FL for fall-winter crops, and CA, Ml and NY for spring-
summer crops.
Label restrictions must be proposed limiting the number of toliar applications permitted per season; the
above-requested data must reflect these numbers.
b. Data are required depicting methyl parathion residues of concern in and on leaf and head lettuce as
follows:
Data reflecting residues of concern in or on leaf and head lettuce after multiple foliar applications by
ground and aerial equipment (in separate trials) at 7-day intervals are needed. Data from EC, D, and
WP treatments applied at 1 Ib ai/A, are required, with formulation comparisons (EC versus D or WP in a
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
within a trial) frcm several locations. Samples must be collected 21 days after the last application.
Geographic distribution must include AZ, CA (central), FL, MI, or WI, NJ or NY, and TX.
Label restrictions must be proposed limiting the number ot foliar applications permitted per season; the
above-requested data must reflect these numbers.
c. Data are required depicting methyl parathion residues of concern in and on spinach as follows:
Data reflecting residues of concern in or on spinach harvested 15 days after the last of several foliar
applications of D, WP and EC formulations, in separate treatments, applied by ground and aerial equip-
ment (in separate trials) at 7-day intervals are needed. The final application must be made at
0.5 Ib ai/A with all previous applications at 1 Ib ai/A (WP and EC) or 0.75 Ib ai/A (D). In
addition, data depiction residues in or on spinach harvested 21 days after the last of several
foliar ground and aerial applications (in separate tests) using WP and EC formulations at \o
I Ib ai/A in separate treatments. Geographic distribution must include CA (central and southern
coast locations), CO, TX and MD or NJ or VA.
Label restrictions must be proposed limiting the number of foliar applications permitted per season; the
above-requested data must reflect these numbers.
ll/ A Brassica leaf vegetable crop tolerance is not appropriate at the present time because additional data
are required to support established tolerances for residues in or on broccoli, cabbage, and mustard
greens.
a. Data are required depicting methyl parathion residues of concern in and on broccoli as follows:
Data depicting residues of concern in or on broccoli harvested 21 days after the last of several
foliar sprays using WP and, in separate tests, EC formulations applied at 7-day intervals by
ground and aerial equipment, in separate trials, at 1.5 Ib ai/A. Tests must also depict residues
in or on broccoli harvested 7 days atter the last of two applications of a D, WP, and EC form-
ulation, in separate tests, at 0.5 Ib ai/A; these applications must be preceded by several foliar
applications applied at 7-day intervals at maximum registered rates (1.5 Ib ai/A for WPs and ECs;
1 Ib ai/A for Ds). Again, both aerial and ground application data are required. Geographic
distribution must include CA (Imperial Valley) an TX for winter-grown crops, and CA (central coast)
and OR for summer-grown crops.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
Label restrictions must be proposed limiting the number ot foliar applications permitted per season; the
above-requested data must reflect these numbers.
b. Data are required depicting methyl parathion residues of concern in and on cabbage as toliows:
Data depicting residues in or on cabbage (with and without wrapper leaves), harvested 21 days after
several toliar applications ot WP, EC, and Heap formulations, in separate tests, at 7-day intervals, at
a rate of 1.5 Ib ai/A application. Trials must also be conducted in which cabbage (with and without
wrapper leaves) samples are collected 10 days after an application ot, in separate trials, D, WP, and EC
formulations at 0.5 Ib ai/A; the final application must be preceded by several foliar applications
applied at 7-day intervals at maximum registered rates (1.5 Ib ai/A tor WP and EC; 1 Ib ai/A tor D).
Both aerial and ground application equipment must be used in these trials, separately.
Data are needed from winter/ spring-planted crops in FL and TX and from summer/fall in CA, NC or NJ, NY
(upstate) and WI.
The registrant(s) must also propose label restrictions limiting the number ot foliar sprays permitted
per crop, which must be supported by the requested residue data.
c. Data are required depicting methyl parathion residues of concern in and on mustard greens as follows:
Data depicting residues of concern in or on mustard greens after the last of several foliar applica-
tions at 7-day intervals by ground or aerial equipment, in separate trials, ot an EC formulation at 1.5
Ib ai/A. Trials must also be conducted in which samples are collected 10 days after an application of,
in separate tests, a D, WP and an EC formulation at 0.5 Ib ai/A; this application must be preceded by
several foliar applications made at 7-day intervals at maximum rates (1.5 Ib ai/A (EC]; 1.0 Ib ai/A
(WPJ; 0.75 Ib ai/A ID}. Separate tests must reflect aerial and ground applications. Trial locations
must include CA, FL, LA or MS or TN, MI or Oil, and TX.
A label restriction must be proposed limiting the number of permissible toliar applications and the
number of permissible postplant broadcast soil applications to kale and mustard greens; the above
requested data must reflect the proposed numbers.
12/ A crop group tolerance is not appropriate at the present time because additional data are required for
residues in or on succulent beans, dried beans (Phaseolus Spp.), succulent peas, dried peas, and soybeans
and the tolerances for residues in or on beans, peas, and lentils (1 ppm) are >5x those for guar beans
(0.2 ppm) and soybeans 0.1 ppm).
a. The established tolerance for residues in or on "beans" is inappropriate. The following data are required:
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
Depiction of residues of concern in or on green lima beans (beans plus pods) after a series of foliar ap-
flications at 7-day intervals, using ground and aerial equipment, in separate tests, as follows: (i)
5 days after the last application of Mcap formulation at 1 Ib ai/A and (11) 21 days after the last
application of, in separate tests, an EC and a WP formulation at 1.5 Ib ai/A. For snap beans, .tests
must be conducted in CA, EL, NY, OR, and WI. For lima beans, tests must be conducted in CA and DE.
Depiction of residues of concern in or on dried beans 15 days after the last of a series of foliar
application of, in separate tests, an EC and a WP formulation at 1.5 Ib ai/A; both aerial and ground
application equipment must be used, in separate trials. Tests must be conducted in CA, MI, NE, and
ND.
Residues must be determined in cannery residue (both dried and snap beans) obtained trcro beans bearing
measurable weathered residues; if residues in cannery residue exceed those found in or on beans, an appro-
priate feed additive tolerance must be proposed. _.
U1
The registrant must propose separate tolerances for residues in or on dried, snap, and lima beans and
approproate tolerance revisions (magnitude) if the data requested indicate toleranceexceeding residues.
A label restriction must be proposed which gives the maximum number of applications allowed per season tor
foliar applications; the data required above must reflect that number.
b. The available data support the established tolerance covering residues of methyl parathion in or on guar
beans. However, additional data are needed to determine whether a feed additive tolerance is needed for
residues in milled products. Thus the following must be submitted:
Residues of concern must be determined in milled products (including guar gum and meal) processed fron
guar beans bearing measurable weathered residues; if resiudes in milled products exceed those found in or
on guar beans, then an appropriate feed additive tolerance must be proposed.
c. The established tolerance for methyl parathion residues in or on lentils is not appropriate.
Therefore, the following data are required:
Residues of concern must be determined in or on lentils harvested 15 days after the last of several foliar
aerial applications of the Mcap folmilation at 0.5 Ib ai/A in 5 gal water/A. Trials must be conducted in
ID and MA, the only states in which use of methyl parathion on lentils is permitted.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
SI58.125 Residue Chemistry (continued)
The registrant roust also propose a label amendment limiting the number of permissible applications per
season to lentils; the maximum permissible number must be reflected in the data requested above.
d. The established tolerance for resiudes in or on "peas" is inappropriate. Separate tolerance must be estab-
lished for residues in or on dried peas and succulent peas. The available data are sparse, with only a
single sample of shelled peas being analyzed tor residues following methyl parathion application. Therefore
the following data are required:
Depiction of the residues of concern in or on dry peas and succulent peas after a series ot foliar applica-
tion at 7-day intervals as follows: 9i) 10 days after the last application of, in separate test, a D, EC,
and WP formulation at 0.5 Ib ai/A (applications made up to 15 days prior to harvest must be at 1 Ib ai/A;
and (ii) 15 days after the last application of, in separate tests, a D, EC, and WP formulation at 1 Ib
ai/A. All of the above application regimens must be conducted in separated tests with aerial and ground
applications. ULV applications must be included in the required tests. Tests must be conducted in DE,
MM, WA and WI. Q
The registrant must also propose a label amendment limiting the number of permissible foliar applications
per season to peas; the maximum permissible number must be reflected in the data requested above.
The registrant(s) must propose separate tolerances for residues in or on dried and succulent peas.
e. The available data are insufficient to support the established tolerance tor methyl parathion residues
in or on soybean seeds, for the following reasons: (i) no data were submitted depicting residues in
or on soybeans following the the registered uses of the D or WP formulations, and (11) insufficient or
no information on sample storage conditions was available for all of the submitted tests. Furthermore,
no data are available depicting residues of concern in soybean processed products. Therefore, the
following additional data are required:v
Depiction of methyl parathion residues of concern in or on soybeans (i) 20 days after two foliar ap-
plication seven days apart, or a D formulation at 1 Ib ai/A; and (ii) 15 days after, in separate
tests, a foliar application at 0.5 Ib ai/A of a D and a WP formulation (this application must be pre-
ceded, 5 days earlier, by an application at 1 Ib/ai A (D formulation) or 0.5 Ib ai/A (WP formulation).
Residue data from soybean hulls, meal, soapstock, crude oil, and refined oil processed from soybeans
bearing measurable, weathered residues (exaggerated rates may be necessary to achieve these residues
levels). If residues concentrate, then appropriate food/feed additive tolerances must be proposed.
-------
TABLE A
GENERIC DATA REQUIREMENTS tOR METHYL PARATHICN
§156.125 Residue Chemistry (continued)
13/ A crop group tolerance for bean vines and hay is not appropriate at the present time for the
tollowing reason:
Additional data or grazing and feeding restrictions are required tor bean vines, bean hay, pea vines,
pea straw/ soybean forage, and soybean hey; refer to the conclusions sections for bean vines and hay,
pea vines and straw, and soybean forage, and hay tor details.
->
The registrant(s) must either propose tolerances for residues in or on bean vines and hay and a pre-
grazing restriction for bean vines or grazing and teeding restrictions. If the registrant(s) choose to
propose tolerances, additional data will be required since the available test data did not adequately
reflect the full regimen of registered uses (or were inadequately described as to methods of treatment,
sample collection, analysis, etc.) and no hay data were submitted. The following data are required:
a. Depiction of residues of concern in or on forage and hay of dried beans. Hay must be sampled 15 days
after the last of a series of foliar applications of, in separate tests, and EC and WP formulation at
1.5 Ib ai/A. Vines must be sampled at regular intervals atter the final treatment, beginning on the
day of final treatment. Tests must be conducted in CA, MI, NE, and ND. Tolerances tor residues
in or on bean vines and hay and a pregrazing interval for bean vines must be proposed. Alternatively,
grazing and feeding restrictions must be proposed.
b. The submitted data concerning residues in or on pea vines are too spare to adequately evaluate the estab-
lished tolerance. Also, no data are available depicting residues in or on pea straw. These data and a
tolerance proposal are required since straw is a raw agricultural commodity ot peas. The following data
are required:
Depiction of the residues ot concern in or on pea vines and straw atter a series ot foliar applications
at 7-day intervals as follows:, (i) 10 days after the last application of, in separate tests, a D, EC,
and WP formulation at 0.5 lb ai/A (applications up to 15 days prior to harvest must be at 1 Ib ai/A );
and (11) 15 days after the last application of, in separate tests, a D, EC, and WP formulation at 1 lb
ai/A. Vines must be sampled at regular intervals atter the final treatment, beginning on the day ot
final treatment. All ot the above application regimens must be conducted in separate tests with aerial
and ground applications. ULV applications must be included in the required tests. Tests must be con-
ducted in UE, MM, WA, and WI.
A tolerance tor residues in or on straw or a teeding restriction must be proposed. Also the 40 Cfr'K
entry ot pea torage must be amended to pea vines, the appropriate commodity definition.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
The registrant must propose a label restriction limiting the number ot permissible foliar applications
per season to peas (currently only the Mcap formulation carries such a limitation), the data requested
above must reflect that number.
c. The available data are insufficient to assess the established tolerance for methyl parathion residues
in or on hay because only two residue values for hay were submitted. Furthermore, since forage and
are raw agricultural commodities of soybeans, tolerances for residues in or on these commodities and
a pregrazing interval for forage must be proposed; alternatively, feeding and grazing restrictions may
be proposed. The available data for forage are inadequate because no D or WP applications were repre-
sented. No data were submitted for straw. The following data are required:
Depiction of methyl parathion residues of concern in or on soybean hay and straw: (i) harvested 2U
days after the last of two foliar applictions of in separate tests, Mcap, EC, and D formulations at I
Ib ai/A; and (11) harvested 15 days after a foliar application ot, in separate tests, an Mcap, EC, D, \o
and WP formulation at 0.5 Ib ai/A which was preceded by a foliar application made 5 days earlier at CD
1 Ib ai/A (Mcap, EC, and D) or 0.5 Ib ai/A (WP). Foliage must be collected at intervals following the
last application in above tests using WP and D formulations. Aerial, ground, and ULV application data
must be submitted. Tests must be conducted in GA, IL, LA, LA, MN, and NC. Tolerances must be proposed
for residues in or on soybean forage and straw and a pregrazing interval must be proposed for forage;
alternatively, feeding and grazing restrictions may be proposed.
14/ A crop group tolerance for fruiting vegetables is not appropriate at the present time for the following
reasons:
Data depicting the residues of concern in or on tomatoes as specified in the tomatoes section. Residue
data from various varieties (bell, chili) or peppers treated at 1.5 Ib ai/A with an EC formulation in
multiple foliar sprays applied at 7-day intervals by ground or aerial equipment in separate trials.
Samplings at 15 days posttreatment are requested from winter trials in FL and TX, and summer trials in
CA, KY, or MI or OH, and NJ.
The registrant(s) must propose label restrictions limiting the total number of applications
per season, which must be supported by the data.
a. The data submitted tor peppers are inadequate to assess the appropriateness ot the established tolerance
for methyl parathion residues. Data deticiences inclyde: no data reflecting a fullseason application
regimen at the maximum registered use rate; no aerial application data, inadequate geographic distri-
-------
TABLE A
GENCRIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
bution ot trials; and insutficient test formulation, sample storage and analytical specifics. Because
ot sufdcently different maximum label rates, the requested data from tomatoes will not be directly
translatable therefore, the following data are required, lit should be noted that these data, per se
would not be appropriate to support a crop group tolerance. Data requirements (for peppers) for estab-
lishing the crop group tolerance were specified in that section.)
Data for the residues of concern in or on various varieties (bell, chili) of peppers from sampled 15
days after multiple foliar applications at 7-day intervals by ground or aerial equipment in separate
trials. Treatments should include EC, D and WP formulations applied at 1.0 Ib ai/A in separate treat-
ments and with side-by-side formulation comparisons (EC versus D or WP in a given location) from several
locations. Field trials must be located in FL and TX for winter-grown crops and in CA, KY or MI or OH,
and NJ for summer-grown crops.
The registrant(s) must propose label restrictions limiting the total number of foliar applications
permitted per crop, which must be supported by the data.
ON
O\ b. The submitted data are not adequate to support the tolerance for methyl parathion residues in or on
tomatoes. The following additional data must be submitted:
Data depicting the residues of concern in or on tomatoes harvested 15 days after multiple foliar ap-
plication at 7-day intervals by ground and aerial equipment (in separate trials) from separate treatments
of an EC and WP at 1.5 Ib ai/A, and of the Mcap and a D at 1.0 Ib ai/A. Also, data are needed from to-
matoes sampled 10 days after a final application of EP, Mcap, WP or D (in separate treatments) at 0.5
Ib ai/A, applied 7 days afrer a full-season treatment regimen of either the EC or Mcap at 1.5 Ib ai/A
applied at 7-day intervals.
Trials should be conducted in central CA, southern (desert) CA, NJ, IN or MI or OH, and TX for spring-
summer crops and in FL for winter-grown tomatoes.
Residue data from wet and dried pomace, puree, catsup and 3uice processed from tomatoes bearing measuar-
able weathered residues. Should residues concentrate in the processed tomato products, the registrant(s)
must propose appropriate food/teed additive tolerances.
The registrant(s) must also propose label restrictions limiting the number of foliar applications permitted
per season, which must be supported by the requested residue data.
-------
GENERIC DATA RETIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
15/ A crop group tolerance for cucurbit vegetables is not appropriate at the present time because the registered
use patterns of use for various crops within the group are too disimiliar.
a. There are insufficient data to assess the tolerance for methyl pa rath ion in or on cucumbers. There-
fore, the following data are needed:
Data for residues of concern in or on cucumbers harvested 10 days after treatment with an EC formulation
at 1.0 Ib ai/A in multiple foliar applications at 7-day intervals by ground or aerial equipment in
separate trials. [Crossover data from D and WP formulations are exempted because their registered use
rates ( <0.25 Ib ai/A) are sufficiently lower than the required EC rate.] Trials are required from CA,
FL, MD, or NJ, MI or OH, NC or SC, and TX.
The registrant(s) must also propose label restrictions limiting the number of foliar permitted per
season, which must be supported by the requested residue data.
b. There are insufficient data to assess the tolerance for methyl parathion in or on melons. There-
tore, the following data are needed:
Data are required depicting the residues of concern in or on cantaloupe from CA and TX, honeydew
from AZ, and watermelon from FL, IN, and NC or SC. The crops should be treated with the EC at 0.164 Ib
ai/A in multiple foliar sprays at 7-day intervals using ground or aerial equipment (in separate trials),
then sampled at 7-day post treatment.
The registrant(s) must also propose label restrictions limiting the number of foliar applications per-
mitted per season, which must be supported by the requested data.
c. No data were submitted for methyl parathion treated pumkins. Therefore, the following data are
needed:
Data depicting the residues ot concern in or on pumpkins harvested 10 days after multiple foliar sprays
at 7-day intervals using the 3 Ib/gal EC (multiple active ingredient product) at 0.24 Ib ai/A. Treatments
applied by ground and aerial equipment in separate trials are requested. Test distribution must in-
clude CA, IL, NJ, and NY.
The registrant(s) must also propose label restrictions limiting the number of foliar applications per
season, which must be supported by the requested residue data.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
d. Data are not available to assess the established tolerance for methyl parathion in or on squash.
Therefore, the following data are required:
Data depicting methyl parathion residues of concern in or on of various varieties ot squash, such as
crookneck types, scallop types (white bush), vegetable marrow types (zucchini), and acorn or butternut
types. The fruit should be treated with multiple foliar sprays (at 7-day intervals) of the EC at 0.15
Ib ai/A by either ground or aerial application equipment (in separate trials), then harvested a 15days
posttreatment. Trials should be conducted in CA, PL, MA, and MI.
The registrant(s) must also propose label restrictions limiting the number of foliar applications per
season, which must be supported by the requested residue data.
16/ A crop group tolerance for pome fruits is not appropriate at the present time because residue data
data and appropriate label restrictions must be submitted for apples (see Apple section tor details). —••
Data depicting the residues ot concern in or on pears sampled 14 days after separate treatments with EC CD
and WP formulations at 1 Ib ai/100 gal, and with the Mcap at 2.0 Ib ai/A (concentrate) in full-season —'
application regimens (at 7-day application intervals) by ground and aerial equipment (at separate loca-
tions). Since it is unlikely that >500 gal/A will be applied to pears, we recommend that the EC and WP
formulations be applied at 5 Ib ai/500 gal/A. Side-by side formulation comparisons (EC versus WP versus
Mcap in a given trial) at the specified maximum rates should be submitted tron several locations. Also,
data are needed from pears harvested 7 days after a final application of the Mcap at 1.0 Ib ai/A, applied
7 days after multiple applications at 7-day intervals of the Mcap formulations at 2.0 Ib ai/A (concentrate).
Field trials must be done in CA, MI, NY, and WA or OR.
The registrant(s) must also propose label restrictions that are conistent tor the crop group that limit
the number and timing of foliar applications permitted per season, which must be supported by the requested
data.
«
a. The submitted data are not adequate to support the established tolerance on apples. Therefore the
following data are required:
Data depicting the methyl parathion residues ot concern in or on apples sampled 14 days atter separate
treatments with an EC formulation at 1 Ib ai/100 gal and with the Mcap at 2.0 Ib ai/A (concentrate) in
full-season application regimens (at 7-day application intervals) by ground and aerial equipment (at
-------
TAULE A
GENERIC DATA REQUIKLMENTS FOR METHYL PARATHICN
S158.125 Residue Chemistry (continued)
separate locations). Since no more that UOO gal/A are likely to be applied to apples, 8 Ib a1/800
gal/A of the EC formulation should be applied. Also, data are needed from apples harvested 7 days
after a final spray ot the Heap at 1.0 Ib ai/A (concentrate) applied 7 days after multiple applications
at 7-day intervals of the Heap formulation at 2.0 Ib ai/A (concentrate). To provide adequate geographic
trials must be conducted In CA, MI, NC, NY, PA or WV, and WA.
Data for methyl parathion residues in wet and dried pomace, and juice processed from apples bearing
measurable weathered residues. Should residues concentrate in the processed apple products, the
registrant(s) must propose appropriate food or feed additive tolerances.
The registrant(s) must also propose label restrictions limiting the number and timing of foliar appli-
cations permitted per season, which must be supported by the residue data.
17/ A crop group tolerance for stone fruits group is not appropriate at the present time for the following
reasons: —>•
O
Residue data from peaches and plums (see Peaches and Plums sections for details] must be submitted. fx>
Residue data are needed from cherries harvested 15 days after the last several (maximum permissible number
to be specified by registrant) foliar high-volume ground applications of an EC formulation at 0.5 Ib
i ai/100 gal. (Since we expect that the maximum gal/A rate to achieve runoff in cherry orchards is 1000, 5
\ Ib ai/A should be applied.] Tests must be conducted in WA, or OR, CA, and MI for sour cherries, and in
1 MI, and UT, for sweet cherries.
' a. The data are insufficient to assess the established tolerance for methyl parathion in or on peaches.
Therefore, the following data are needed:
i
1 Residue data from peaches harvested 14 days after the last ot several foliar high volume ground applications
of a WP and an EC formulation in separate tests, at 1 Ib ai/100 gal. (Since we expect the maximum gal/A
rate to achieve runoff in peach orchards is 500, 5 Ib ai/A should be applied.] These tests must be
conducted in CA, and SC.
The registrant must also propose a maximum number ot permissible seasonal applications to apricots,
peaches and nectarines; this number must be supported by the data requested above.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
k
b. The data are insufficient to assess the established tolerance for methyl parathion in or on plums.
Therefore, the following data are needed:
Data depicting residues in or on plums harvested 14 days after the last of several high-volume ground
foliar applications of a WP and, in separate tests, and EC formulation at 1 Ib ai/lOU gal. [Since we
expect no more than SOU gal/A will be needed to achieve runoff, 5 Ib ai/A must be applied.) Tests must
be conducted in CA, OR, WA, and ID.
The registrant must propose a label restriction limiting the number of permissible applications per
season for foliar use on plums and cherries; the data required above must reflect that number.
Residues must be determined in prunes processed from plums bearing measurable weathered residues. If
residues are found to concentrate in prunes, an appropriate food additive tolerance must be proposed.
18/ A crop group tolerance for small fruits is not appropriate at the present time for the following
reasons:
Additional residue data are required to support the established tolerances for grapes, straw-
berries, and gooseberries.
a. No data were submitted pertaining to residues of methyl parathion in or on gooseberries.
The following data are required:
Data depicting residues in or on gooseberries collected IS days after multiple ULV aerial and, in
separate tests, ground applications at seven day intevals of an EC at 0.5 Ib ai/A. Tests must be
conducted in MI, CA, and WA.
The registrant must propose a label restriction limiting the number of foliar applications to
gooseberries; the data requested above must reflect the proposed maximum number of applications.
b. The submitted data do not support the established tolerance tor residues of methyl parathion in
or on grapes. Therefore, the following data are required:
Depiction of methyl parathion residues of concern in or on grapes harvested 14 days atter the last of
multiple applications at seven-day intervals of an Mcap formulation at 3 Ib ai/A. Separate tests must
be conducted with ground and aerial applications (including ULV aerial). Studies must be conducted
in CA., and NY.
-------
TAB!
GENERIC DATA REQUIREMENTTTFOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
The registrant must also propose a label restriction limiting the number of foliar applications permitted
per season; the requested data must reflect this label restriction.
Data reflecting residues of concern in the processed products of grapes. Residue data should be obtained
from raisins, raisin waste, juice, wet pomace and dried pomace, processed from grapes bearing measurable,
weathered residues. If residues concentrate in any of these processed products, appropriate food/feed
additive tolerances must be proposed.
c. The submitted data do not support the established tolerance for residues of methyl parathion in or
on strawberries. Therefore, the following data are required.
Depiction of methyl parathion residues ot concern in or on strawberries sampled 14 days after, in
separate tests, the last of multiple foliar applications of an EC formulation and a WP formulation at
0.79 Ib ai/A. Separate tests must also be conducted with ground and ULV aerial applications of these
formulations.
The registrant must also propose a label restriction limiting the number of foliar applictions permitted j~
per season; the requested data must reflect this label restriction.
19/ A crop group tolerance for tree nuts is not appropriate because a usage proposal and residue data tor
walnuts, almonds and pecans are needed.
The registrant(s) must propose consistent use patterns (rates, timing, total number of applications per
season) and label restrictions for methyl parathion for all commodities of the group.
a. Data are insufficient to assess the adequacy of the established tolerances in or on almonds and
almond hulls. Therefore, the following data are required:
Data depicting methyl parathion residues in or on almonds and almond hulls sampled after a full-season
application regimen (through hull-sRlit) at 6.0 Ib ai/A applied at 7-day intervals by ground and
aerial equipment in separate trials. Data from at least three locations (San Joaquin Valley, Sacramento
Valley and central coast areas) in CA are requested.
The registrant(s) must also propose label restrictions limiting the number of foliar applications
permitted per season, which must be supported by the requested residue data. The registrant(s) must
also indicate the minimum Pill resultant from tying the Codex MRL final application to the hull-split
growth stage.
-------
TABLE A
GENERIC DATA REQUIREMkNrS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
b. No residue data were submitted to support the existing tolerance tor methyl parathion residues in or
on pecans. The following data are required:
Data depicting methyl parathion residues ot concern in or on pecans treated with the 3 Ib/gal EC (MAI)
at the maximum labeled rate in a full-season application regimen (through shuck-split) applied at
7-day intervals by ground and aerial equipment in separate trials. Data are requested from trials
conducted in AL or GA, MM and OK or TX.
The registrant(s) must also propose label restriction limiting the number ot foliar applications
permitted per season; express the maximum application rate in Ib ai/A or restrict the maximum
spray volume if the rates are expressed in Ib ai/100 gal; and indicate the minimum resultant PHI it
the final application is tied to the shuck-split growth stage.
We recommend that the current label restriction against feeding treated shucks to livestock be deleted
because pecan shucks are not fed to livestock.
20/ A crop grouping tolerance for cereal grains is not appropriate because the registered use patterns
are too dissimilar and additional data are required for corn, rice, sorghum and wheat.
a. The available data are sufficient and adequate to support a 1 ppm tolerance for residues of methyl
parathion in or on sweet corn (kernels plus cob, husk removed) harvested 3 days after multiple
applications at rates through 1.0 Ib ai/A applied at 2- to 5-day intervals. However, the regis-
trant (s) must:
Propose a tolerance tor residue of methyl parathion in or on sweet corn (kernels plus cob, husk,
removed), per se. Propose label restrictions limiting the number of foliar applications allowed per
season, and limiting the application interval to 2- to 7-day.
b. The available data are insufficient to assess the established tolerance for residues ot methyl
parathion in or on field corn. Therefore, the following data are required:
Data depicting methyl parathion residues of concern in or on field corn grain harvested 12 days after
the final application ot a tull-season foliar treatment ot the Mcap and EC formulations (in separate
treatments) at 1.0 Ib ai/A applied at 7-day intervals by ground and aerial equipment in separate trials.
O
C/T
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
Comparative data from side-by-side treatments of the EC and Mcap tram several trials are desireable.
Data from ultralow volume, aerially applied treatments and chemigation (through sprinklers) treatments
using the Mcap are needed trom separate locations. Trials should be conducted in AL or GA, CA, IL,
MN, NC or VA, NE, Ori and TX.
The registrant(s) must propose a tolerance tor residues ot methyl parathion in or on tieId corn grain,
per se.
Residues must be determined in the crude and retined oils and appropriate food additive tolerances
must be proposed.
Additional residue data are required tor wet and dry milled products processed from field corn
grain bearing measurable weathered residues. If residues concentrate in any of the processed com-
modities, a food/teed additive tolerance must be proposed.
The registrant(s) must propose a label restriction limiting the number of applications per season,
which must be supported by the requested residue data.
c. The data are insufficient to assess the established tolerance for residues of methyl parathion in
or on rice. Therefore, the following data are required:
Data depicting the residues of concern in or on rough rice collected 15 days after a full-season
treatment regimen (at 7-day intervals) applied by aerial equipment (applications by ground equipment
are not needed). Data are needed from separate treatments of the Mcap and WP at 0.75 Ib ai/A. Treat-
ments with the EC at 0.79 Ib ai/A are also required; however, if the registrant(s) elect to revise the
EC labels to a maximum rate of 0.75 Ib ai/A tor consistence with the other formulations, the lower
rate may be used. Trails should be conducted in AR, CA, LA and TX.
«
Residue data for the milled products ot rice, including hulls, bran and polished rice, fractionated
trom rough rice bearing measurable weathered residues. Because the submitted data indicate that
residues will concentrate in the hull fraction, we anticipate that appropriate food/feed additive
tolerances will be needed.
The registrant(s) must also propose label restrictions limiting the number of foliar applications
permitted per season, which must be supported by the requested data.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
d. The available data are inadequate to support the interim tolerance tor residues ot methyl parathion
in or on rye. However, tlie residue data requested tor wheat is translatable to rye.
The registrant(s) should propose an appropriate permanent tolerance for residues of methyl parathion
in or on rye grain and, if warranted by the milling data, appropriate food and feed additive tolerances
for residues in the milled products or rye. Further, we recommend that the current interim
tolerance for residues of methyl parathion in or on rye be deleted from 40 CFR 180.139 when the per-
manent tolerance is established.
e. The available data do not support the established tolerance for methyl parathion residues in or
on sorghum. Therefore, the following data are required:
Data depicting methyl parathion residues ot concern in or on sorghum grain sampled 21 days after
treatment with full-season application regimens of an EC at 1.0 Ib ai/A applied at 7-day intervals by
ground and aerial application equipment in separate tests. Tests must be conducted in KS or MO , Nt;
or SD, NM or western TX, and southern TX.
Residues must be determined in the dry milled products [flour and tine grits (fine bran plus germ]
and starch from sorghum grain bearing measurable weathered residues. If residues concentrate in
these products, the registrant(s) must propose appropriate tood additive tolerances (Milling residue
data for corn may be translated to sorghum).
Data for methyl parathion residues in or on seeds of sweet sorghum (sorgo) are also required from
field trials conducted in AL or GA or MS, and IA, using the test parameters prescribed for grain
sorghum. Residue data are required for syrup processed trora sweet sorghum bearing measurable weathered
residues. A food additive tolerance will be required if processing results in residue concentration
in the syrup. Alternatively, data tor sweet sorghum and its processed commodity may be exempted it the
registrant(s) submit an appropriate label restriction excluding methyl parathion use on sweet sorghum.
The registrant(s) must also propose label restrictions limiting the number ot toliar applications
permitted per season, which must be supported by the data.
f. The available data are not adequate to assess the tolerance tor residues ot methyl parathion in or
on wheat. Therefore, the following data are required:
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
S158.125 Residue Chemistry (continued)
Data are required depicting the methyl parathion residues ot concern in or on wheat sampled 15-days
after two foliar sprays at 0.75 Ib ai/A which were preceded by multiple applications of either a
D, EC, or WP (in separate treatments) at 1.25 Ib ai/A. A 7-day application interval is required as
are ground and aerial treatments (in separate trials). Separate treatments using EC, Mcap, D, and WP
formulations at 0.75 Ib ai/A in the tinal sprays are needed, field trials should be conducted in
CA, KS or NE, MI or OH, NC or VA, ND, TX and WA.
Residue data are also required trom wheat harvested immediately (0-day) after two treatments consisting
of a given formulation (EC, WP, D and Mcap) at 0.25 Ib ai/A applied 7 and 15 days after the multiple
foliar sparys (7-day application interval) of the same formulation at 0.75 Ib ai/A atter heads form,
but at 1.25 Ib ai/A before heads focm. Data should be sumbitted from such treatment regimens of all
formulations ( in separate treatments) from the geographic distribution presecibed above.
Residue data are required from wheat sampled at "normal" harvest following multiple applications at
1.25 Ib ai/A at 7-day intervals through grain head formation. Data are required from separate treatments
with EC, WP and D fromulations from the test locations specified above. The registrant(s) must submit CD
label restrictions for this use that clarify the final application timing labeled as "after heads
form" lie, does this timing refer to grain heads still in the boot (Feekes stage 10.0) or to heads
emerged trora the boot (Feekes stages 10.1-10.5)1. The interval between this application timing and
normal" harvest must also be indicated and supported by the data.
H
Residue data are required for wheat bran, flour, middlings and shorts milled trom grain bearing measur-
able weathered residues. Should resideues concentrate in the milled products, the registrant(s) must
propose appropriate food/teed additive tolerances.
The registrant(s) must also propose label restrictions limiting the number of foliar applications
permitted per season, which must be supported by the requested residue data.
21/ A crop group tolerance for the Forage, Fodder, and Straw of Cereal Grains is not appropriate at the present
time for the following reasons:
Tolerances have not been established tor residues ot methyl parathion in or on: forage, hay and straw
of barley, oats, rye and wheat; straw on rice; fodder and silage of corn; or hay and silage ot sorghum.
Additional data are required to assess the established tolerances for residues in or on corn forage and
sorghum forage and fodder.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
t
S158.125 Residue Chemistry (continued)
The registrant(s) must also propose label restrictions limiting the number of toliar applications
allowed per crop, which must be supported by the requested residue data.
d. The available data are insufticient for a tolerance assessment for wheat forage, hay or straw.
Therefore, because wheat forage, hay and straw are raw agricultural commodities the registrant(s)
must either:
Propose feeding and grazing restrictions for wheat forage, hay and straw; or
Submit tolerance proposals, a pregrazing interval tor forage, and data depicting the residues of
concern in or on:
1. Wheat forage, hay and straw harvested immediately (0-day) after an application of an Heap, EC, D
and WP at 0.25 Ib ai/A applied 7 days after multiple foliar sprays (7-day application interval) of
the same formulation at 0.75 Ib ai/A after the heads form but at 1.25 Ib ai/A before the heads
form. Data are needed frornsuch a treatment for each formulation type (in separate treatments)
applied by ground and aerial equipment in separate tests from the geographic distribution outlined
below.
2. Wheat hay and straw harvested 15 days after and forage harvested at various intervals after the
last of two applications (of each formulation type in separate treatments) at 0.75 Ib ai/A which
were preceded by multiple applications (of either D, EC or WP formulation in separate treatments)
at 1.25 Ib ai/A. A 7-day application interval is required for all treatments. Aerial- and ground
-applied treatments, in separate trials, are needed.
3. Wheat straw harvested at "normal" harvest following multiple applications (full-season treatment
regimen) at 1.25 Ib ai/A at 7-day intervals through grain head formation. Data are required from
EC, D and WP formulations applied in separate treatments at several locations and from aerial- and
ground-applied treatment locations. Field trials should be conducted in CA, KS or NE, MI or OH,
NC or VA, ND, TX and WA.
The registrant(s) must also propose label restrictions clarifying the final application timing label-
led as "after heads form" (i.e., does this timing refer to grain heads still in the boot (Feekes
stage 10.0) emerged from the boot (Feekes sta'ges 10.1 -10.5?). The interval between this application
timing and "normal" harvest must also be indicated and supported by the data.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
S158.125 Residue Chemistry (continued)
* The registrant(s) must also propose label restrictions limiting the number of toliar applications
permitted per season, which must be supported by the requested residue data.
22/ The Grass Forage, Fodder and Hay Group tolerance is not appropriate for the following reasons:
Data are required depicting the residues of concern in or on grass hay harvested fifteen days after
the last of multiple foliars at 7-day application intervals of EC and Mcap formulations (in separate
tests) at 0.79 and 0.75 Ib ai/A respectively. Separate tests must be conducted using ground and aerial
application equipment. Hay curing conditions and practices must be adequately described. Tests must
be conducted at locations representative of bemiudagrass (southern-southeastern U.S.), bluegrass
(northeasternmidwestern U.S.) and bromegrass (upper midwestern and western U.S.) production regimens.
Tests must be conducted under both irrigated and unirrigated production systems. A tolerance tor re-
sidues in or on hay must be proposed.
The registrant(s) must also propose label restrictions limiting the number of foliar applications —••
permitted per season, which must be supported by the requested residue data. CD
23/ The Non-Grass Animal Feeds (Forage, Fodder, Straw, and Hay) Group tolerance is not appropriate
for the following reasons:
Additional residue data are required for alfalfa, a representative ccmnodity (refer to the Alfalfa
section).
Data are needed depicting residues of concern in or on clover forage and hay collected 15 days after a
foliar appliction of, in separate tests, D, EC, and WP formulations at 1 Ib ai/A, preceded by applications
made up to 20 days prior to harvest at 7-day intervals at the maximum allowed rate of 1.25 Ib ai/A.
Separate tests also must be conducted depicting residues 20 days after the last of multiple foliar
applications at 1.25 Ib ai/A for D, EC, and WP formulations. Forage must be collected at intervals
following the last treatment in all tests. These studies must include tests in which ground and
ULV aerial applications made. Tests must be conducted in CA, 10, MN, NY, and MI. The registrant must
limit the number of applications/ season and the data required must reflect that number. Also, pregrazing
intervals for forage must be proposed.
a. The data do not adequately support the established tolerances tor residues of methyl parathion in or
on Alfalfa Forage and Hay. Therefore, the following data are required:
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
§158.125 Residue Chemistry (continued)
The registrant(s) must propose label restrictions limiting the number of toliar applications per
season to alfalfa and establish pregrazing intervals tor D, WP, and EC formulations equal to the PHIs.
If the reyistrant(s) chooses to limit the number of applications to no more than two per season, then
the presently avliable data provide adequate support for the tolerance for residues in or on hay and
may be used to support a tolerance revision for residues in or on forage (increase). It the
registrant(s) chooses to propose more than two applications per growing season, then the following
data are needed.
Depiction of residues of concern are required in or on hay harvested 15 days atter a toliar application
of the D, EC, Mcap and WP formulations, in separate tests, at 1 Ib ai/A preceded by a fullseason
treatment regimen of multiple applications at 7-day intervals at 1.25 Ib ai/A (D, EC, WP) or 1 Ib ai/A
(Mcap) up to 20 days prior to harvest. Forage should be collected 15 days after the last Mcap treatment
'and at intervals following the last D, WP and EC treatment.
Separate tests must also be conducted dipicting residues in or on hay harvested 20 days after the last
of multiple foliar treatments of the D, EC, and WP formulations, in separate tests, at 1.25 Ib ai/A.
Forage should be collected at intervals following the final treatment. Pregrazing intervals must be
proposed for D, WP and EC formulations. These studies must include test in which ground and ULV
aerial applications are made. Tests must be conducted in CA (San Josquin Valley), CA (Imperial Valley)
or A2, ID, KS or OK, ND or SD, NY, OH and WI.
Data depicting residues of concern in or on alfalfa seed harvested on the day of the final application
of a full-season treatment regimen consisting of treatments made at 7-day intervals using an EC formula-
tion at 1.25 Ib ai/A. Ground and aerial application equipment must be used in separate trials.
Tests must be conducted in CA, WA, and NV.
24/ The established tolerance for residues of methyl parathion in or on artichokes is not sufficient.
Therefore, the following data are required:
Residue data are required from artichokes harvested 7 days after the last of multiple applications at
7-day intervals of a WP, EC, D and encapsulated formulation at 1.0 Ib ai/A, using high and low volume
ground equipment for WP, EC and Mcap formulations. The tests must be conducted in CA.
The registrant must also propose a label amendment limiting the number of toliar applications per season.
This number must be represented in the data requested above.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
»
§158.125 Residue Chemistry (continued)
25/ The established tolerance for residues of methyl parathion in or on cottonseed is not sutticlent.
Therefore, the following data are required:
Depiction of residues of concern are required in or on cotton forage harvested at intervals after, and
mature cottonseed samples harvested seven days after the last of several foliar ground and aerial applica-
tions, in separate tests, of an EC formulation at 3 Ib ai/A. Applications must be made three days apart.
Residues in or on cottonseed must also be determined immediately after the last of two applictions made at
3-day intervals of, in separate tests, a D formulation at 1.5 Ib ai/A and WP, EC, and Heap formulations at
1 Ib ai/A. These applications must be preceded by several applications, made at 3 day intervals up to 7
days prior to harvest, with the D, Mcap and WP formulations at 1.5 Ib ai/A and the EC at 3 Ib ai/A.
Tests must be conducted in TX and CA or MS. A tolerance for residues in or on cotton forage and a pre-
grazing interval must be proposed; alternatively, a feed restriction may be proposed.
Data depicting the residues of concern in meal, hulls, soapstock, and crude and refined oil, processed
from cottonseed bearing measurable, weathered residues. Should residues concentrate in processed products,
appropriate food/feed additive tolerances must be proposed. The registrant must also proposed a label
restriction limiting the number of foliar applications permitted per season, the data requested above
must reflect that number.
26/ No data were submitted to support the established tolerance for residues of methyl parathion in or on
hops. The following data are required:
Data are required depicting the residues of concern in or on mature fresh hops harvested 15 days after
the last of multiple applications of an EC and WP formulation, in separate tests, at 1 Ib ai/A using, in
separate tests, aerial and high low volume ground equipment. These tests must be conducted in WA, OR,
or ID;
i
Data depicting the residues of concern in dried hops and spent hops processed from hops bearing measurable
weathered residues. Should concentration of residues be found in the processed products, appropriate
food/feed additive tolerances must be proposed.
The registrant(s) must propose a label restriction limiting the number of applications permitted per
season; this number being reflected in above requested data.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
27/ The available data to support the established tolerance tor residues ot methyl pa rath ion in or on
peanuts are not sutficient. Therefore, the following data are required:
Residue data are required from peanuts (nutmeats), hulls, and hay harvested 15 days after the last of
several foliar applications of an EC and D formulation (in separate tests) at 0.375 and 0.5 Ib ai/A.
These tests must utilize (separately aerial, and high and low volume ground equipment. Vines must be
sampled at intervals following the last treatment. Tests must be performed in GA, or AL, NC, and TX.
Tolerances must be proposed for residues in or on peanut vines, hay, and hulls, and a pregrazing interval
must be proposed for vines. If feeding and grazing restrictions are proposed, no data or tolerance
proposals are required for vines or hay. Processing data for peanut meal, crude oil, soapstock, and
refined oil to determine the concentration of residues upon processing. These data must be generated
frcm peanuts bearing measurable, weathered residues.
The registrant(s) must propose a label restriction limiting the number of applications permitted per
season; this number being reflected in above requested data.
28/ The available data are inadequate to support the established tolerance for residues of methyl parathion
in or on rapeseed. Therefore, the following data are required:
Residue data are required from rape seed harvested 15 days after the last of several multiple applications
ot the 4 Ib/gal EC formulation at 0.5 Ib ai/A in 3 gal of water per acre. These tests must be conducted
in ND by aerial application.
Data depicting residues in meal and oil processed trom rapeseed bearing measurable weathered residues.
Should residues be found to conqentrate in rapeseed oil or meal, then appropriate food/feed additive
tolerances must be proposed. (Note: Processing data for corn, cottonseed and peanuts may be translated
to rapeseed).
The registrant must propose a label restriction limiting the number ot foliar applications permitted to
rape, with above requested data reflecting that number.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.125 Residue Chemistry (continued)
29/ No data were submitted to support the established tolerance for residues of methyl parathion in or on
safflower. The following data are required:
i
Residue data from safflower seed harvested after multiple foliar applications (up to flowering) with' a
WP and EC formulation, in separate tests, at 0.5 Ib ai/A, utlizing, (in separate tests) aerial and
ground (high and low volume) equipment. These tests must be conducted in CA, and MT.
Residue data are required from safflower seeds harvested 60 days after the last of two foliar aerial
application a 1.5 Ib/gal EC using 5 gal water/A. This test must be conducted in CA.
Processing data are required for safflower meal and oil utilizing safflower seeds bearing measurable,
weathered residues. If residues concentrate upon processing, then appropriate food/teed additive
tolerance must be proposed. (Note: Processing data for corn, cottonseed, and peanuts may be translated
to safflower seed).
30/ The available data are inadequate to support the established tolerance tor residues of methyl parathion
in or on sunflower seeds. Therefore, the following data are required:
Residue data are required from sunflower seeds harvested 30 days and from forage harvested at intervals
after the last of three foliar applications of an EC formulation at 1 Ib ai/A, made at 5-day intervals,
utilizing aerial and high and low volume ground equipment in separate tests. These tests must be
conducted in ND. A tolerance for residues in or on forage and a pregrazing interval must be proposed.
Alternatively, registrant(s) may place a grazing restriction on the label.
Processing data tor sunflower meal, hulls, crude oil, and refined oil, processed from sunflowers bearing
measurable, weathered residues are required. Should residues be found to accumulate upon processing,
then appropriate food/feed additive tolerances must be proposed. (Note: Processing data for corn,
cottonseed and peanuts may be translated to sunflower.)
3I/ The available data are not sufficient to assess the exposure to man of residues of methyl parathion
in or on tobacco. The following data are required:
Information indicating the formulation actually used to generate the submitted residue data and the
mode of application used.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR MCTHYL PARATHION
§158.125 Residue Chemistry (continued)
Pyrolysis products derived from methyl paratluon treated tobacco must be characterized and the level of
resiude in smoke must be quanitified. (14C-Ring labeled methyl parathion must be used for identification
of pyrolysis products.)
The registrant(s) must propose a label restriction limiting the number ot foliar applications permitted
per season.
Information clarifying if residues were methyl parathion or ethyl parathion.
32/ These data are reserved pending the results of the requested animal metabolism data. These data will be
evaluated to determine the need for tolerances in animal products, meat and milk, poultry and eggs.
33/ Tolerance petitions must be submitted for those commodities stated throughout the residue chemistry
footnotes. However, since methyl parathion TMRC exceeds 100 percent of the ADI, the Agency will not
accept any new uses or petitions for tolerances-either group tolerances or otherwise. Registrants)
are urged to cancel uses and tolerances (especially tolerances which have no federal registrations)
to reduce the ADI.
34/ If new metabolites are identified and a new analytical method is required, samples may be needed.
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR METHYL PARATWON
Use
Data Requirement
Composition!/ Pattern^
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA S 3(C)(2)(B)7
Timeframes for Data
Submission3/
§158.130 Environmental Fate
DEGRADATION STUDIES-LAB;
161-1 - Hydrolysis
Photodegradation
161-2 - In water
161-3 - On soil
161-4 - In Air
METABOLISM STUDIES-LAB;
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
162-4 - Aerobic Aquatic
MOBILITY STUDIES;
TGAI or PAIRA A,B,C,G
TGAI or PAIRA A,B,C,G
TGAI or PAIRA A,G
TGAI or PAIRA A
TGAI or PAIRA A,B,G
TGAI or PAIRA C
TGAI or PAIRA
TGAI or PAIRA,
163-1 - Leaching and TGAI or PAIRA
Adsorption/Desorption
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
TEP
TEP
C
C
A,B,C,G
A
A
NO
NO
No
No
No
No
No
No
No
No
NO
Yes
Yes
Yes
Yes
9 Months
9 Months
9 Months
9 Months
Yes 27 Months
Reserved^/
Yes
Yes
Yes
Yes
Yes
27 Months
27 Months
12 Months
12 Months
15 Months
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR METHYL PARATHION
Data Requirement
Does EPA Have
Data To Satisfy
Use This Require-
Compositionl/ Pattern2/ ment? (Yes, No
or Partially)
Must Additional Data
Be Submitted Under
Bibliographic FIFRA § 3(c)( 2)(B)?
Citation Timefraines for Data
SutmissionV
§158.130 Environmental Fate (continued)
DISSIPATION STUDIES-FIELD:
164-1 -
164-2 -
164-3 -
164-4 -
164-5 -
Soil
Aquatic (Sediment)
Forestry
Combination and "
Tank Mixes
Soil, Long-term
TEP A,B
TEP C
TEP G
N/R
TEP A,C
No
NO
No
-
NO
Yes
Yes
Yes
No
ReservedV
27 Months
27 Months
27 Months
ACCUMULATION STUDIES:
165-1 -
165-2 -
165-3 -
165-4 -
165-5 -
Rotational Crops
(Confined)
Rotational Crops
(Field)
Irrigated Crops
In Fish
In Aquatic Nontarget
PAIRA A,C
TEP A,C
TEP , C
TGAI or PAIRA A,B,C,G
TEP G
No
No
No
No
No
Yes
Yes6/
Yes
Yes
Yes
39 Months
50 Months
39 Months
12 Months
12 Months
Organisms
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
§158.130 Environmental Fate (continued)
I/ Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active ingredient,
radiolabelled; TEP = Tjpical end-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food;
C = Aquatic, Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food;
G = Forestry; H = Domestic Outdoor; I = Indoor.
3/ Data must be submitted within the indicated tuneframes, which begin on the date of the Guidance Document
(see front cover for this date).
£/ These data are not required if acceptable anaerobic aquatic metabolism data are provided.
j>/ The requirement for these data depend on the results of the terrestrial field dissipation studies.
6/ May be required, depending upon test results frcm confined crop studies (165-1).
CO
-------
TABLE A ,
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Does EPA Have Must Additional Data
Data To Satisfy Be Submitted Under
Use This Require- Bibliographic FIFRA § 3(c)(2)(B)?
Data Requirement Compositionl/ Pattern^/ ment? (Yes, No Citation Timeframes for Data
or Partially) Submission3/
§158.135 Toxicology (continued)
•
ACUTE TESTING:
81-1
81-2
81-3
81-7
- Oral
- Dermal
- Inhalation
- Acute Delayed
Neurotoxicity
TGAI A,B,C,D,E,F
TGAI A,B,CfD,E,F
TGAI A,B,C,D,E,F
TGAI A,B,C,D,E,F
Yes
' No
No
No
GS001530U5 No
Yes!/
Yes4/
Yes4/
9 Months
9 Months
9 Months
SUBCHRDNIC TESTING:
82-1
82-2
82-3
82-4
82-5
- 90-Day Feeding -
Rodent (rat, mouse)
Non-rodent (dog)
- 21-Day Dermal - Rabbit
- 90-Day Dermal - Rabbit
- 90-Day Inhalation - Rat
- 90-Day Neurotoxicity -
TGAI A,C,E
TGAI A,B,C,D,E,F
TGAI A,B,C,D,E,F
TGAI A,B,C,D,E,F
TGAI
Yes
No
No
No
No
00074299,00072513 No
00072512 No
Reserved V
Reserved V
- Reserved^/
Yes4/
15 Months
Hen/Mammal
82-6 - Special Subchronic
Testing - 2 species
-Rat,
-Dog
TGAI A,C,E
No
No
Yes<>/ 12 months
YesV 12 Months
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
Data Requirement
§158.135 Toxicology (continued)
CHRONIC TESTING:
Use
Composition^/ Patternj2/
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, N6
or Partially)
Bibliographic
Citation
Must Additional Data
Be Su tm it ted Under
FIFRA S 3(c)(2)(B)?
Time frames for Data
Submission^/
.
83-1 - Chronic Toxicity - TGAI
2 species
- Rodent (Wistar Rat)
(S-D Rat)
- Non-rodent (Dog)
83-2 - Oncogenicity Study - TGAI
2 species
- Rat (Wistar Rat)
(S-D Rat)
(F344 Rat)
- Mouse (preferred)
83-3 - Teratogenicity - TGAI
2 species:
- Rat
- Rabbit
83-4 - Reproduction - Rat TGAI
2-generation
MuTAGENICITY TESTING
84-2 - Gene Mutation (Ames Test) TGAI
84-2 - Structural Chromosomal
Aberration
TGAI
A,C,E
A,C,E
A,B,C,D,E,F
A,B,C,D,E,F
A,B,C,D,E,F
A,B,C,D,E,F
Partially
Partially
Partially
Partially
Yes
Partially
No
Partially
Partially
Yes
GSOO 1531)06,
GSOO 15 3007
00093895
GSOO 153006,
GS00153007
00127239
GS00153008
GS00153009
00119087
Yes8/
Yes*/,?/
Veal/,*/
Yes9/
No
Yes8/
Yes
Yes8/
Yes8/
No
Yes
Yes
o
50 Months
6800153010,00124901
GS00153011,00132949
No
GS00153012,00124901 No
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHICN
Data Requirement
Use
Does EPA Have
Data To Satisfy
This Require-
Co^npositionV Pattern^/ ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIERA § 3(c)(2)(B)?
Timeframes for Data
Submission^/
§158.135 Toxicology (continued)
84-4 - Other Genotoxic Effects
SPECIAL TESTING
TGAI
A,B,C,D,E,F
85-1 - General Metabolism PAI or PAIRA
85-2 - Dermal Penetration Choice
86-1 - Domestic Animal Safety Choice
Yes
No
No
No
GS00153012,00124901
GS00153011
No
Yes 24 Months
Yes 12 Months
Yes 24 Months
r\j
I/ Composition: PAI = Pure active ingredient; PAIRA = Pure active ingredient, radiolabelledj Choice
several test substances determined on a case-by-case basis.
Choice of
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic,
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry;
H = Domestic Outdoor; I = Indoor.
3/ Data must be submitted within the indicated timeframes, which begin on the date of the Guidance Document
(see front cover for this date).
«
4/ Data to fulfill these requirements may be submitted from the open or published literature.
5/ Contingent upon the outcome of the worker exposure analysis (see reentry section).
6/ The registrant(s) must provide reasonable and acceptable approaches to determine the "no-observed-etfect level"
for the eye toxicity based on possible functional retinal impairment. The Agency is prepared to accept studies
such as electroretinograms to assess these effects. The mechanism of abnormal gait in female rats and sciatic
nerve degeneration including determination of a NOEL in rats must be addressed. Protocols must be submitted to
K Agency within three months from the date ot this Guidance Document. Electroretinogram data must be submitted
he Agency within 16 months from the date of thia«tandard and the abnormal gait and sciatic nerve data^ must be
itted within 8 months from the date this standa^^A issued (see front cover for this date).
-------
§158.135 Toxicology (continued)
7/ The registrant(s) must provide reasonable and acceptable approaches to determine the NOEL for cholinesterase
inhibition in the chronic dog study (data are to be submitted within 24 months from the issuance of this
standard). Additionally, reasonable and acceptable approaches to determine the eye toxicity based on functional
retinal impairment must be provided. The Agency is prepared to accept studies such as electroretinograms to
assess these effects (data trust be submitted within 16 months from the issuance of this standard). Protocols
tor these studies must be submitted to this Agency within three months from the date of this Guidance Document
(see front cover tor this date).
8/ These supplementary studies may be upgraded following submission of additional data. These data must be sub-
mitted no later than 12 months trom the issuance of this standard.
9/ Although this study meets the Agency's guidelines, additional information on the historical background of the
spontaneous tumor incidences are required. These data must be submitted within 6 months from the date of this
Guidance Document.
ro
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR METHYL PARATHION
Use
Data Requirement
Composition^/ Pattern2/
Does EPA Have
Data To Satisfy
This Require-
ment?" (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA § 3(C)(2)(B)7
TimeEcames foe Data
SubmissionV
§158.140
132-1
132-1
133-3
133-4
§158.142
201-1
201-1
§158.75
Reentry Protection
- Foliar Dissipation
- Soil Dissipation
- Dermal Exposure
- Inhalation Exposure
Spray Drift
- Droplet Size Spectrum
- Drift Field Evaluation
Other Exposure Data
TEP
TEP
TEP
TEP
TEP
TEP
A,B,C,D,E,F
A,B,C,D,E,F
A,B,C,D,E,F
A,B,C,D,E,F
A,B,C,D
A,B,C,D
A,B,C,D,E,F
NO
No
NO
NO
No
No
NO
Yes4/
Yes4/
Yes4,V
Yes4 , V
Yes7/
Yes7/
Yes6,8/
27 Months
27 Months
27 Months
27 Months
27 Months
27 Months
27 Months
I/ Composition: TEP = Typical end-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic,
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry;
H = Domestic Outdoor; I = Indoor.
«
3_/ Data must be submitted within the indicated timeframes, which begin on the date of the Guidance Document (see front
cover for this date).
4/ For each representative crop/site the registrant is required to propose an acceptable reentry interval based on
~~ either: a) data on dissipation of foliar and/or soil residues of parathion (decline curve), on human
exposure to those residues, and on toxicity of parathion; or b) determination of that time beyond which
There are no detectable, dislodgeable residues remaining in the worker environment.
hJ
-------
S158.140 Reentry Protection (con't)
5/ Exposure data may be estimated from foliar dissipation data {132-11 according to the Allowable Exposure Method of
Subdivision K of the Pesticide Assessment Guidelines or may be determined experimentally.
6/ Passive dosimetry (patch) studies on mixer/loaders and applicators during airblast, ground boom, and aerial operations
involving emulsifiable concentrates, wettable powders, microencapsulated, and dust formulations are required. These
studies must be conducted in compliance with the Agency's Pesticide Guidelines, Subdivision U, Applicator Exposure
Monitoring. The protocols must be submitted to and approved by the Agency prior to the initiation of the studies
7/ Ttie spray drift droplet spectrum and field evaluation may be done together in order to evaluate the droplet spe'ctrums
that are associated with actual field use patterns.
8/ Quantitative data must be submitted regarding the permeability of various materials used for protective clothing and
equipment (gloves, boots, protective garments, etc.) for all liquid formulations. If these data are not available,
the they must be generated using methods described in American Society of Testing and Materials (ASTM) 739-81-Standard
Test Method for Resistance of Protective Materials to Permeation by Hazardous Liquid Chemicals.
IV)
-£=>.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Use
Data Requirement Compositionl/ PatternV
§158.145
Does EPA Have
Data To Satisfy
This Require- Bibliographic
ment? (Yes, No Citation
or Partially)
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Timeframes for Data
SubmissionV
Wildlife and Aquatic Organisms
AVIAN AND MAMMALIAN TESTING
71-1 -
71-2 -
71-3 -
71-4 -
71-5 -
Acute Avian Oral Toxicity
Avian Subacute Dietary
Toxicity
Wild Mammal Toxicity
Avian Reproduction
Simulated and Actual
Field Testing
- Mammals and Birds
TGAI
TEP
TGAI
TEP
TGAI
TGAI
TEP
TEP
A,B,C,D,G
A,B,C,D,G
A,B,C,D,G
A,B,C,D,G
A,B,C,D,G
A,B,C,G
A,B,C,G
A,B,C,G
i
Yes
Yes
Yes
Partially
Yes
No
Yes
Partially
GS00153014, 00020560
05008363
GS00153015
00022923, GS00153016
00102329
GS00153017, GS00153018
GS00153019
-
00128792, 00128793
00102372, 00090488
00061213, GS00153020
GS00153021
No
No
No
YesV
No
Yes
No
YesV
9 Months
24 Months
48 Months
AQUATIC Ow^rtNISM TESTING
72-1 -
Freshwater Fish Toxicity
Coldwater
Warmwater
TGAI
TEP
TGAI
A,b,C,D,G
C,D
A,B,C,D,G
Yes
Partially
Yes
00003503, 00128791
00061214, 00128791
00003503, 000919U7
GS00153022
No
Yes0/
No
— -— - -^9
9 Months
^
f\J
TEP
C,D
00102405, 00076148
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Data Requirement Compos itionl/
72-2 - Acute Toxicity to
Freshwater Invertebrates
72-3 - Acute Toxicity to
Estuarine and Marine
Organisms
72-4 - Fish Early Life Stage,
and Aquatic Invertebrate
Life-Cycle
Estuarine
Fish
Invertebrate
Freshwater
Fish
Invertebrate
72-5 - Fish - Life-Cycle
72-6 - Aquatic Organism
TGAI
TEP
TGAI
TEP
TGAI
TGAI
TGAI
TEP
TGAI
TEP
i
TGAI
TGAI
Use
Pattern2/
A,B,C,D,G
C,D
A,C,D
C,D
A,C,D
A,C,D
A,C,D
A,C.D
A,C,D
A,C,D
A,C,D
A,C,D
Does EPA Have
Data To Satisfy
This Require- Bibliographic
ment? (Yes, No Citation
or Partially)
Yes 00003503, 00128790
Partially 00128790, 00083028
Yes 00066341V, 05000819
No
No
Partially 00066341
Partially GS00153022, 00128791
Partially GS00153022, 00128791
Partially 00128790
Yes 00128790
No
NO
Must Additional Data
Be Submitted Under
FIFRA § 3(C)(2)(B)7
Time frames for Data
SubnissionV
No
.
YeSb/ 9 Months
No
Yesf/ 12 Months
•
yeg10/ 15 Months
Reserved^!/
Yesl2/ 15 Months
Yes_M/ 15 Months
Yesl3/ 15 Months
NO
Reserved IV
YeglS/ 12 Months
Accumulation
72-7 - Simulated Field Testing TEP
- Aquatic Organisms
- Actual Field Testing TEP
-Aquatic Organisms
A,C,D
A,C,D
Partially 00035176
Partially 00035176
Months
Yesl6/ 48 Months
ON
-------
§158.145 Wildlife and Aquatic Organisms
_!/ Composition of the material to be tested is technical grade unless otherwise specified in footnotes.
_2/ The use patterns are coded as follows: A = Terrestrial, Pood Crop; B = Terrestrial, Non-Food Crop; C = Aquatic,
Food Ctop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic
Outdoor; I = Indoor.
, !
V Data must be submitted within the indicated tine frames, which begin on the date of the Guidance Document (see front
cover for this date).
4/ The data requirement for an avian dietary study with upland gamebirds has been fulfilled. The study must also be
conducted with a waterfowl species.
V Full field testing of the effects of methyl parathion on birds and mammals is required. The use sites with which we
ate concerned include: forests, alfalfa, wheat, cotton, grapes, sunflowers, lettuce, soybeans, rice. If the regis-
trant wants to conduct testing on fewer use sites, justification must be given. The testing must quantify mortality,
survivability and reproduction of birds (waterfowl, passerines and upland gamebirds) and small mammals. The species
that will be studied will be determined by the testing site. More than one geographic area for a specific use site may
be necessary if there are significant environmental differences among the geographic areas. The registrant must k
consult with the Agency prior to initiation of any field testing. Protocols must be submitted to and approved by the ...
Agency prior to initiation of any study. ..
6/ These studies were conducted with Penncap-M. Other formulations need to be tested if they will enter the aquatic
environment from the use on rice and to control mosquitoes.
T/ The first two studies listed were conducted with Penncap-M. The last two studies listed were conducted with stauffer
formulations. If other formulations used on rice and to control mosquitoes are significantly different from the ones
tested, they will also need to be tested.
8/ Study 100066341 was audited by the Agency. Final determination of the status of tests on white shrimp and spot
~~ (static tests) have not been completed* However, the data on oyster larvae, mysid shrimp, sheepshead minnow (static
tests) and spot (flowtnrough test) fulfill Guideline requirements.
9/ Testing must be conducted with typical formulations used on rice and to control mosquitoes in estuarine areas.
1Q/ An estuarine fish early lifestage is required to support the rice' and mosquito control uses. The requirement for
terrestrial food crop uses is reserved pending environmental fate data and a model-determined EEC.
ll/ This study was audited by the Agency. If the Agency determines that this study is deficient, then another one must
be submitted to support the rice and mosquito control uses. The tequitement for terrestrial food crop uses is le-
pending environmental fate data and a model-determined EEC.
-------
§158.145 Wildlife and Aquatic Organisms (con't)
12/ Study 100128791 is deficient because only two concentrations of technical methyl parathion were tested and a no-
effect level was not determined for both technical methyl parathion and Penncap-M. Study GS00153024 Is deficient
because the raw data for the biological and water chemistry parameters are missing. If the caw data are submitted,
the study can be reevaluated and may fulfill the Guideline requirements.
13/ Study 100128790 is deficient because only two concentrations of technical methyl parathion were tested and a no-
effect was not determined.
14/ This study is reserved pending the submission and review of the requested environmental fate data.
15/ Refer to 165-4 and 165-5 for these requirements.
16/ The aquatic data show that aquatic invertebrates can be severely impacted by the movement of methyl parathion from
treated fields to adjacent aquatic sites. The effects on fish populations is less clear. Data from a field test
and estimates from runoff modeling indicate fish may not be significantly affected; however the field and modelling
data did not take Into account potential exposure from drift of the pesticide to aquatic sites. These aquatic
data indicate the need for well-designed full-scale field studies which examine the effects on fish and aquatic —*
invertebrates as well as monitor residues in the water and sediment. These studies can either be designed as |\)
mesocosms (simulated field study) or full field study (actual field Study). Testing sites include, presently, oo
cotton, rice, soybeans, alfalfa and mosquito control sites. The registrant must inform the Agency which of the two
field techniques it wants to use to fulfill this data requirement. The Agency will provide guidelines for proper
protocol development. If the mesocosm method is chosen the system must be inoculated with'biota and allowed to
develop for one year prior to treating the system with the pesticide. The treatment year will be based upon the
season(s) of application of the pesticide. There are to be at least three treatment levels based on estimated en-
vironmental concentrations for drift and surface runoff and three replicates per treatment plus three controls. A
mesocosm study may be needed for each agricultural site if predicted drift and surface runoff and geographic regions
of use are significantly different for each site. If the actual field study method is used there must be at least
one reference pond and one treatment pond per agricultural site. There must be a baseline year of study and a treat-
ment year for each pond. The treatment year will be determined by the application season for each agricultural site.
Based upon the results of the field/mesocpsm testing, aquatic residue monitoring of additional sites may be needed.
The Agency must approve the protocols prior to initiation of the studies.
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR METHYL PARATHION
Use
Data Requirement
Composition^/ PatternV
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Time frames for Data
SubmissionV
§158.155 Nontarget Insect
NONTARGET INSECT TESTING -
POLLINATORS!
141-1 - Honeybee acute
contact toxicity
141-2 - Honeybee - toxicity
of residues on
foliage
141-4 - Honeybee subacute
feeding study
141-5 - Field testing for
pollinators
NONTARGET INSECT TESTING -
AQUATIC INSECTS;
142-1 - Acute toxicity to
aquatic insects
142-1 - Aquatic insect
life-cycle study
142-3 - Simulated or actual
field testing for
aquatic insects
143-1 - NONTARGET INSECT
TING - PREDATORS
thru
143-
PARASITES
TCAI
TEP
(Reserved)4/
TEP
(Reserved)V
i
(Reserved )5/
(Reserved)V
(Reserved)V
A,B,G
A,B,G
A,B,G
Yes
Yes
Yes
00066220
00074486
No
No
00138662, 00138663
00138667
No
-------
§158.155 Nontarget Insect (con't)
\J Composition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food;
C = Aquatic, Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food;
G = Forestry; H = Domestic Outdoor; I = Indoor.
3/ Data must be submitted within the indicated tuneframes, which begin on the date of the Guidance Document
(see front cover for this date).
4/ Reserved pending development of test methodology.
5/ Reserved pending Agency decision as to whether the data requirement should be established.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR METHYL PARATHION
Does EPA Have
Data To Satisfy
Use This Requi re-
Data Requitement Composition!/ Pattern^ ment? (Yes, No
or Partially)
§158.155
§158.150
121-1
Nontarget Insect
Plant Protection
- TARGET AREA EP B,D No
PHYTOTOXICIIY
Must Additional Data
Be Submitted Under
Bibliographic FIFRA § 3(c)(2)(B)7
Citation Timeframes for Data
SubmissionV
No3/
NONTARGET AREA PHYTOTQXICITY
122-1
122-1
122-2
123-1
123-1
123-2
124-1
124-2
TIER I
- Seed Germination/ TCAI B,D No
Seedling Emetgence
- Vegetative Vigor TCAI B,D No
- Aquatic Plant Growth TCAI B,D No
TIER II
- Seed Germination/ TCAI B,D No
Seedling Emergence
- Vegetative Vigor TCAI B,D No
- Aquatic Plant Growth TCAI B,D No
TIER III
- Tetrestnal Field TEP B,D No
- Aquatic Field TEP B,D No
rt — : 1- := s ~ — TT : • n : 1 —
NoV
NoV
NoV
1
NoV
NoV
NoV
NoV
2/ Th^^B patterns ate coded as follows: A = Tettestrial^^d Ctop; B = Terrestrial, Non-Food Crop; C = Aqua
Foo^Prop; D = Aquatic, Non-Food; E = Gieenhouse, Food ^^B F = Greenhouse, Non-Food; G = Fotestry; H = Don>
3/ These tequirements ate generally waived unless it 19 bel^^red thete is a phytotoxicity problan.
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING METHYL PARATHION
Guideline Citation and
Name of Test 5
§158.120 Product Chemistry •
Product Identity:
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning
Materials and Manufacturing
Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Methods to Verify
Certified Limit
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
Test
iubstancej/
MP
MP
MP
MP
MP
MP
MP
MP
MP
Guidelines
Status
R
R
R
CR
R
R
R
R
R
Are
Reqi
Yes
IX]
IX)
IX]
IX]
IX]
IX)
IX)
IX]
IX]
Data Must Be
Data Submitted Within
lired? Timeframes Listed
No Below2/
*
M 6 Months
Q 6 Months
Q 6 Months
Q 12 Months
M 12 Months
H 12 Months
M 6 Months
M 6 -Months
M b Months
::::::::::::::::
r\>
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING METHYL PARATHION
Guideline Citation and
Name of Test
§158.120
Physical
63-7 -
63-12
63-14
63-15
63-16
63-17
63-18
63-19
63-20
Product Chemistry (continued)
Test
SubstanceV
Guidelines
Status
Are Data
Required?
Yes No
Data Must Be
Submitted Within
Time frame s Listed
Below2/
and Chemical Characteristics (continued)
Density, Bulk Density, or
Specific Gravity
- PH
- Oxidizing or Reducing Action
- Flarmnability
- Explodability
- Storage Stability
- Viscosity
- Miscibility
- Corrosion Characteristics
MP
MP
MP
MP
MP
MP
MP
MP
MP
R
CR
CR
CR
R
R
CR
CR
R
(X)
(X)
IX]
[X]
(X)
[X]
[X]
IX]
IX]
u
n
IJ
o
IJ
o
o
o
fl
7
7
7
7
7
16
7
7
7
Months
Months
Months
Months
Months
Months
Months
Months
Months
Other Requirements;
64-1 - Sutmittal of samples
MP
CR
: : : : :
IX]
t : ;
I/ MP = Manufacturing-use Product; R = Required; CR = Conditionally Required.
2/ Data must be submitted within the indicated timeframes, which begin on the date ot the Guidance
Document (see front cover tor this date).
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS TOR MANUFACTURING-USE PRODUCTS CONTAINING METHYL PARATHION
Data Requirement
Composition^/
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
FIFRA $ 3(c)(2)(B)7
Timeframes for Data
Submission I/
§158.135 Toxicology
ACUTE TESTING
81-1 - Acute Oral Toxicity - Rat
81-2 - Acute Dermal Toxicity
- Rabbit
MP
MP
No
No
Yes 9 Months
Yes 9 Months
81-3
81-4
81-5
81-6
- Acute Inhalation Toxicity
- Rat
- Primary Eye Irritation
- Rabbit
- Primary Dermal Irritation
- Rabbit
- Dermal Sensitization
- Guinea Pig
MP
MP
MP
MP
No
No
No
No
No3/
No3/ \
No3/
No3/
I/ Composition: MP = Manufacturing-use product.
2/ Data must be submitted within the indicated timeframes, which begin on the date of the Guidance Document
(see front cover for this date).
3/ These data are waived since parathion labeling bears the highest possible toxicity category (I) and is a
Restricted Use chemical. However, if another toxicity category is desired, data must be submitted
for the above studies.
-------
135
SUMMARY-1
LABEL CONTENTS
40 CFR 162.10 requires that certain specific labeling
statements appear at certain locations on the label. This
is referred to as format labeling. Specific label items listed
below are keyed to the table at the end of this Appendix.
Item 1. PRODUCT NAME - The name, brand or trademark is
required to be located on the front panel, preferably centered
in the upper part of the panel. The name of a product will
not be accepted if it is false or misleading.
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
Item 3. NET CONTENTS - A net contents statement is
required on all labels or on the container of the pesticide.
The preferred location is the bottom of the front panel
immediately above the company name and address, or at the end
of the label text. The net contents must be expressed in the
largest suitable unit, e.g., "1 pound 10 ounces" rather than
"26 ounces." In addition to English units, net contents may
be expressed in metric units. [40 CFR 162.10(d)]
Item 4. EPA REGISTRATION NUMBER - The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase "EPA Registration No.," or "EPA
Reg. No." The registration number must be set in type of a
size and style similar to other print on that part of the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency.
[40 CFR I62.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment
number, preceded by the phrase "EPA Est." is the final estab-
lishment at which the product was produced, and may appear-
in any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of
the package if the EPA establishment number on the immediate
container cannot be clearly read through such wrapper or container.
[40 CFR 162.10(f)]
Item 6A. INGREDIENTS STATEMENT - An ingredients statement
is required on the front panel. The ingredients statement must
contain the name and percentage by weight of each active ingredient
and the total percentage by weight of all inert ingredients.
The preferred location is immediately below the product name.
The ingredients statement must run parallel with, and be clearly
distinguished from, other text on the panel. It must not be
placed in the body of other text. [40 CFR I62.10(g)]
-------
136
SUMMARY-2
Item 6B. POUNDS PER GALLON STATEMENT - For liquid agricul-
tural formulations, the pounds per gallon of active ingredient
must be indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS - Front panel
precautionary statements must be grouped together, preferably
within a block outline. The table below shows the minimum type
size requirements for various size labels.
Size of Label Signal Word "Keep Out of Reach
on Front Panel Minimum Type Size of Children"
in Square Inches All Capitals Minimum Type Size
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - The statement
"Keep Out of Reach of Children" must be located on the front
panel above the signal word except where contact with children
during distribution or use is unlikely. [40 CFR 162.10(h)(1)(ii)]
Item 7B. SIGNAL WORD - The signal word (DANGER, WARNING,
or CAUTION) is required on the front panel immediately below
the child hazard warning statement. [40 CFR 162.10 (h)(1)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, dermal,
or inhalation toxicity, the word "Poison" shall appear on the
label in red on a background of distinctly contrasting color and
the skull and crossbones shall appear in immediate proximity to
the word POISON. [40 CFR 162.10(h)(1)(i)]
Item 7D. STATEMENT OF PRACTICAL TREATMENT - A statement
of practical treatment (first aid or other) shall'appear on
the label of pesticide products in toxicity Categories I,
II, and III. [40 CFR I62.10(h)(1)(iii)}
Item 7E. REFERRAL STATEMENT - The statement "See Side
(or Back) Panel for Additional Precautionary Statements" is
required on the front panel for all products, unless all
required precautionary statements appear on -the front panel.
[40 CFR I62.10(h)(1)(iii)]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING - The
precautionary statements listed below must appear together
on the label under the heading "PRECAUTIONARY STATEMENTS."
The preferred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the three hazard warning statements must be headed by the
appropriate hazard title. [40 CFR 162.10(h)(2)].
-------
137
SUMMARY-3
Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a
hazard exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard, the
route(s) of exposure and the precautions to be taken to avoid
accident, injury or damage. [40 CFR 162.10(h)(2)(i)]
Item 8B. ENVIRONMENTAL HAZARD - Where a hazard exists to
non-target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. [40 CFR 162.lO(h)(2)(ii)]
Item 8C. PHYSICAL OR CHEMICAL HAZARD - FLAMMABILTTY
Precautionary statements relating to flammability of a product
are required to appear on the label if it meets the criteria
in the PHYS/CHEM Labeling Appendix. The requirement is
based on the results of the flashpoint determinations and
flame extension tests required to be submitted for all products.
These statements are to be located in the side/back panel
precautionary statements section, preceded by the heading
"Physical/Chemical Hazards." Note that no signal word is
used in conjunction with the flammability statements.
Item 9A. RESTRICTED USE CLASSIFICATION - FIFRA sec. 3(d)
requires that all pesticide formulations/uses be classified
for either general or restricted use. Products classified
for restricted use may be limited to use by certified applicators
or persons under their direct supervision (or may be subject
to other restrictions that may be imposed by regulation).
In the Registration Standard, the Agency has (1) indicated
certain formulations/uses are to be restricted (Section IV
indicates why the product has been classified for restricted
use); or (2) reserved any classification decision until
appropriate data are submitted.
The Regulatory Position and Rationale states whether
products containing this active ingredient are classified
for restricted use. If they are restricted the draft label(s)
submitted to the Agency as part of your application must
reflect this determination (see below).
If you do not believe that your product should be classified
for restricted use, you must submit any information and
rationale with your application for reregistration. During
the Agency's review of your application, your proposed classi-
fication determination will be evaluated in accordance with
the provisions of 40 CFR 162.11(c). You will be notified of
the Agency's classification decision.
-------
138
SUMMARY-4
Classification Labeling Requirements
If your product has been classified for restricted use,
the following label requirements apply:
1. All uses restricted.
a. The statement "Restricted Use Pesticide" must
appear at the top of the front panel of the label. The
statement must be set in type of the same minimum size
as required for human hazard signal word (see table in 40
CFR 162.10(h) (1) (iv)
b. Directly below this statement on the front panel,
a summary statement of the terms of restriction must
appear (including the reasons for restriction if specified
in Section I). If use is restricted to certified applicators,
the following statement is required: "For retail sale
to and use only by Certified Applicators or persons
under their direct supervision and only for those uses
covered by the Certified Applicator's Certification."
2. Some but not all uses restricted. If the Regulatory
Position and Rationale states that some uses are classified
for restricted use, and some are unclassified, several courses
of action are available:
•
a. You may label the product for Restricted use.
If you do so, you may include on the label uses that
are unrestricted, but you may not distinguish them
on the label as being unrestricted.
b. You may delete all restricted uses from your
label and submit draft labeling bearing only unrestricted
uses.
c. You may "split" your registration, i.e., register
two separate products with identical formulations, one
bearing only unrestricted uses, and the other bearing
restricted uses. To do so, submit two applications for
reregistration, each containing all forms and necessary
labels. Both applications should be submitted simul-
taneously. Note that the products will be assigned
separate registration numbers.
Item 9B. MISUSE STATEMENT - All products must bear the
misuse statement, "It is a violation of Federal law to use
this product in a manner inconsistent with its labeling."
This statement appears at the beginning of the directions
for use, directly beneath the heading of that section.
-------
139
SUMMARY-5
Item 10A. REENTRY STATEMENT - If a reentry interval
has been established by the Agency, it must be included on
the label. Additional worker protection statements may be
required in accordance with PR Notice 83-2, March 29, 1983.
Item 10B. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage and disposal statements. These
statements are developed for specific containers, sizes, and
chemical content. These instructions must be grouped and
appear under the heading "Storage and Disposal" in the directions
for use. This heading must be set in the same type sizes as
required for the child hazard warning. Refer to Appendix II,
STOR, PEST/DIS, and CONT/DIS to determine the storage and
disposal instructions appropriate for your products.
Item IOC. DIRECTIONS FOR USE - Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate to
protect the public from fraud and from personal injury and to
prevent unreasonable adverse effects on the environment.
[40 CFR 162.10]
•
COLLATERAL LABELING
Bulletins, leaflets, circulars, brochures, data sheets,
flyers, or other written or graphic printed matter which is
referred to on the label or which is to accompany the product
are termed collateral labeling. Such labeling may not bear
claims or representations that differ in substance from those
accepted in connection with registration of the product. It
should be made part of the response to this notice and submitted
for review.
-------
SUMMARY-6
LABELING REQUIREMENTS OF THE FIFRA, AS AMENDED
ITEM
1
2
3
4
5
6A
6B
7
7A
7B
LABEL ELEMENT
Product name
Company name
and address
Net contents
EPA Reg. No.
EPA Est. No.
Ingredients
statement
Pounds/gal Ion
statement
Front panel
precau t ionary
statements
Keep Out of Reach
of Children
(Child hazard
warning)
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
All products
All products
Liquid products
where dosage
given as Ibs.
ai/uniV. area
All products
All products
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
None
None
None
None
Front panel
Front panel
Front panel
Front panel
Front panel
PREFERRED
Center front
panel
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel,
immediately
before or
following
Reg. No.
Immediately
following
product name
Directly below
the main
ingredients
statement
Above signal
word
Immediately
below child
hazard
warning
COMMENTS
If registrant is not the producer, must
be qualified by "Packed for . . .,"
"Distributed by. . .," etc.
May be in metric units in addition to
U.S. units
Must be in similar type size and run
parallel to other type.
May appear on the container instead of
the label.
Text must run parallel with other text
on the panel.
All front panel precautionary statements
must be grouped together, preferably
blocked.
Note type size requirements.
Note type size requirements.
o
-------
SUMMARY-7
ITEM
7C
7D
7E
8
8A
8B
LABEL ELEMENT
Skull & cross-
bones and word
POISON (in red)
Statement of
Practical
Treatment or
First Aid
Referral
statement
Side/back panel
precaut ionary
statements
Hazards to
hunans and
donestic
animals
Environmental
hazards
APPLICABILITY
OF REQUIREMENT
All products
which ate Cat-
egory I based
on oral, der-
mal, or inhala-
tion tonicity.
All procucts
in Categories
I, II, and III
All products
where pre-
cautionary
labeling
appears on
other than
front panel.
All products
All products
in Categories
I, II, and III
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
Category I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped with
side panel
precautionary
statements.
Front panel
None
«
None
None
PREFERRED
Both in close
proximity to
signal word
Front panel
for all.
Top or side
of back panel
preceding
directions
for use >
Same as above
Same as above
COMMENTS
Must be grouped under the headings in
8A, 8B, and 8C; preferably blocked.
Must be preceded by appropriate signal
word.
Environmental hazards include bee
caution where applicable.
-------
SUMMARY-W
ITEM
8C
9A
9B
IDA
10B
IOC
LABEL ELEMENT
Physical or
chemical
hazards
Restricted
block
Misuse
statement
Reentry
statement
Storage and
disposal block
Directions
fop use
APPLICABILITY
OF REQUIREMENT
All pressurized
products, others
with flesh
points under
150°F
All restricted
products
All products
PR Notice 83-2
or aa determined
by the Agency
All products
All products
PLACEMENT ON LABEL
REQUIRED
None
Top center
of front
panel
Immediately
following
heading of
directions
for use
In the
directions
for use
In the
directions
for use
None
PREFERRED
Same as above
Preferably
blocked
Immediately
after misuse
statement
Immediately
before
specific
directions
for use or
at the end of
directions
for use
(tone
COMMENTS
Refer to Appendix II guide
PHYS/CHEM
Includes a statement of the terms of
restriction. The words "RESTRICTED USE
PESTICIDE" must be same type size as
signal word.
Required statement is:
"It is a violation of Federal law
to use this product in a manner
inconsistent with its labeling."
Must be set apart and clearly distin-
guishable from from other directions
for use.
Refer to Appendix II guides STOR,
CONT/DIS, and PEST/DIS for further
information and required statements.
May be in metric as well as U.S. units
fX)
-------
I—environmental Prelection Agency
$ 1*2-10
it obtained the data from anothc
(identify); applicant co
11 publication, applicant
>y of the data from EPA;
The applicant shall lubmit
Bplication a statement that
L evaluation of the properties/ ef fl-
cacyAand safety of the foray
' product.,
• not comic
data u supporting the appl
except \he following data:
data the applicant
(1)
mittcd
thiSSeCtll
(3)
safety
ents. rathe'
end-use
(1)
regulations.
EPA under i
data
tub-
(b)of
Kemptio!
jed
Pood, Drug.
(e) If the applicant
item of data hi, sui
section was gen
pense of) anothi
ly submitted the
predecessor. Ui
ary L 1910. to
for registration.
permit, or
use to an
reregistraUon
and the original data
reached writ
amount and
any compenssjtlon
able on
NcXlXOXli)/
of the applioition>. the
submit to fPA a
has
to the
e product's acute Ingredi-
than to the ss£ety of the
ucttad
tolerances.
to each
, submitter:
od additive
and other
the Federal
Act.
vs that any
under th|>
(or at the cz>
who oriclaal-
to XPA (or itt
on or after Janu*
irt an appUcation
xperlaeotal use
;nt addin* a new
or for
the applicant
submitter hare
on the
payment of
may be pay-
section
approral
'Ucant •****!
t that he
Identified
(1) A
intent to,!
taw the;
iUfleaUon of tae
• f or reflstrat
ppUcanfs
Inclutf-
I product]
(2) Aa1 offer to pay the
, with regard to the approval
' application, to the
rXFRA sections
(CX2XDK
'An identtflcatton of the
, to which the offer applies
f) An offer to
to
of i
/(5) The applicant's
the amount
i to be paid:;
f) If the applicant's product co;i-
any active ingredient other
that are present solely
Incorporation Into the product,
formulation, of one or/more
ered pesticide producu
from another producer.
then tbeXapplicant shall alM comply
with | Itte-t at to such active ingre-
dient. and Vhe appUcation/shall con-
tain an acknpwledcment tnat for pur*
poaea of P13TLA section 3(cxlXD) the
application reues on (ud any result-
bi< retistratiookshould/be refirded as
If it were based to th«/Admiznstntor's
eonsideraUon of ) ue/ollowtnr dau:
(1) All data submlRed or specifically
cited by the appl^ant In support of
the registration.
(2) Xach othe^lte^ of data tn the
Afency's fQes wi
(1) Concerns me propertiea or effects
of any such SOUTC tncrecaent. and
(U) Is one/of the typo Not data that
Z3»A would/equire to be submitted for
sclfHttftc ftnew by EPA iT\the appli-
cant sou/ht the tnitial
under FTFRA Section J(cx^)
'with composition and
ed uses' identical to those proi
the applicant's product.
rcquiremenu tn effect on\
EPA approves the appl
application.
J. <. aatf » of riTRA. at «a«
1M«(M«,)
(44 TR nwi. toy it irrti
(a) Oenmol— (1) Contnt* o/ U*
labtL rrery pesticide products shall
bear a label containing the informa-
tion specified by the Art md the recu-
Utlons in this Part. The contents of a
label must show clearly and promi-
nently the foQowtnsj:
(1) Tbe^name, brand, or trademark
under which the product to sold as pre-
scribed in paragraph (b) of this sec-
tion:
(U) The name and address of the
producer, ^registrant, or person for
whom produced as prescribed in para-
graph (e) of this section:
UU) The net contents as prescribed
in paragraph (d) of this section;
-------
I ui.it
Till* 40— tVolacMwN of I
O>»ft*r I—tr»vltsnm*»t*< frolocHoti Afeiwy
(continue*))
| IM 10
alltl to It. The registration number
ind the required Identifying phrase
•hall not appear In such a muiner M
to su(ge*t or Imply recommendation
or endorsement ol the product by the
Agency
(II Preprint e*(aMI*Ammt* rryit-
Irsdon **mbrr The producing e*tab-
llshtntnt registration number preced-
ed by the phraae ' EPA BsC". of the
final establishment at which the prod-
opt was produced may appear In any
suitable location on the label or Imme-
dltle container It must appear on the
wrapper or ouUMe container o( the
package H the EPA establishment reg
tstratlon number on the Immediate,
container cannot be clearly read
through such wrapper or container
(|) faeredlmf ((alcmeiil—41) Gener-
al. The label ol each p*eUc*d* product
must bear a italement which contain*
the name and percent*** by weight of
each active Ingredient, the total per-
. eentege by weight of all Inert Ingredi-
ent*; and If the pe*Udde contain* ar-
senic In any form, a statement of the
percentage* of total and waUf-aoluble
arsenic calculated a* elemental ar-
•enlc. The active Ingredient* must be
deiltnated by the term "aeUrg Ingredi-
ent* and the Inert Ingredient* by the
term "Inert Ingredient*." or UM singu-
lar lonns of theee term* when appro-
prUU. Both term* *h*ll be In the
same type she. be aligned to the Mine
margin and be equally prominent. The'
itatement "Inert Ingredient*, none** I*
not required for pesticide* which con-
tain 100 percent active Ingrwdtentg.
Unte*i the Ingredient lUtement I* a
complete analyst* of the pesticide, the
term "analysis" shall not be lued a* a
heading for the Ingredient statement.
ID Porttto* o/ iMftvrfleiit itafamrat
III The Ingredient statement I* nor
mally required en the front panel of
the label II there I* an ouUtde con-
tainer or wrapper through which the
Ingredient statement cannot be clearly
read, the Ingredient statement must
*Uo appear on such outetde container
or wrapper If the stse or form of the
package makes It Impracticable U
place the Ingredient statement on the
front panel of the label, permission
may be granted for the Ingredient
statement to appear elsewhere
(III The text of the Ingredient state-
ment must run parallel with other
text on the panel on which It appear*.
and muat be clearly distinguishable
from and mu*t not -be placed In the
body of other teal
O) rV*wie* to ft* lued In Infrerflmf
itntrmntL The name u*ed for each In
gredlent shall be the accepted
common name. II there Is one. fol
lowed by the chemical name The
common name may be u*ed alone only
II It Is well known. II no common name
ha* been established. the chemical
name alone shall be us«d. In no ea*e
will the UM of a trademark or proprt
etary name be permitted unlc** such
t
name nas oeen IK>DCV~«. —
name by UM Administrator under UM
authority of Section IMcMt)
14) St*ttm**lt o/ prreewtape*. The
percentage* of Ingredient* shall be
stated In term* of welght-to-wclght.
The sum of percentage* of the active
and the Inert Ingredient* ahall be 100.
Percentage* shall not be expressed by
a range of value* such a* "71-J»%.* If
the use* of the pesticide product are
expressed a* weight of active Ingredl
ent per unit are*, a statement of th*
weight of active Ingredient per unit
volume of the pesticide formulation
shall also appear In UM Ingredient
statement.
(i) Jcewracv of stataf pert**!****.
The percentage* given shall b* a* pre-
cis* a* possible reflecting good manu-
facturing practice II there may b* un-
avoidable variation between manufae
luring batches. UM vain* stated for
each active Ingredient ahall b* the
lowest percentage which may b* prev-
ent.
(f) Dvtorlorwflow. PMtldde* which
change In chemical composition slg
nlltcanUy must meet th* following la
bellng requirements:
(I) In ca*e* where It Is determined
that a peaUctde formulation change*
Chemical composition significantly.
th* product must bear the following
statement tat a prominent position on
the label- "Not for sal* or use alter
Idatel"
(II) The product must meet all label
claims up to the expiration Urn* Indl
rated on the label
(1) frwrt (wrdUnU Th* Adminis-
trator may require the name of any
Inert Ingredlentlsl to be listed In the
Ingredlrnt statement II he determine*
that *uch Ingredient)*! may pone *
hajiard to man or the environment
(III Wanting! »n4 ftrctullonurf
f(*femr*'f Required warnings and
precautionary statements concerning
the general areas of lexicological
haitard Including haitard to children.
environmental haxard. and physical or
chemical hazard fall Into two groups;
those required on the front panel of
the labeling and (hone which may
appe«r elsewhere HneHllr require
menl* concerning rnntenl plarentenl
type she. and prnmlitenrr arr given
below
III Mreiilmf from! prtnrl •Imlrmftl*
With the esrepHnn of the rhllit
hiuutrd warning ulalement ll>e leal rr
quired on the fmnl nawl ol the labrl
Is determined by the Tnxtrlly Caletin
ry ol the pesticide The rale«nry I* MI
signed on the bnuls of (lie hlghenl
haxard shown by any of the Indlralnrs
In the table below
(I) HsmsK Au«nf
rojrMly C*(r*orv I All pesticide prod
ucte meeting the criteria of Toxtclty
Category I shall bear on the front
punel the slgnsl word ' Danger " In ad
dllton If the product was assigned to
Toildty Category I on the basis of It*
oral. Inhalation or dermal toxlclty (as
distinct from skin and eye local el
fectel the word "Poison" shall appear
In red on a background of distinctly
contrasting color and the skull and
crossbones shall appear In Immediate
proximity to the word poison."
(B> Tbxldlr Caterer* II All pest!
ride product* meeting the criteria of
ToiMty Category II shall bear on tht
front panel the signal word "Warn-
ing "
ICI roztclfv Cslrponr III All pesU
elde product* meeting the criteria of
Toxlclty Category III shall bear on
the Iront panel the signal word "Cau-
tion"
IDI Toriett* Cairpory IV All pestl
«Jde products meeting the-criteria of
Toxlclty Category IV shall bear on th*
front panel I he signal word 'Caution "
IRI V»t o/ ifensl inorwi Use of any
slsnal wordtsl amorlaled with a higher
Toxlclty Category Is not permit ted
except when the Atenry determine
that such labeling U nm+ntj In pre
vent unreasonable adverse effects on
man or the environment. In no nme
•hall mor* than one human hamrd
signal word appear on the frnnt panel
of a label
(III OkIM A***rrf w>*nilHg Rvery pes
Uctde product label shall bear on the
front panel the statement keep out of
reach of children" Only In mws
where th* likelihood of ronUrl with
children during distribution, market
Ing. storage or use U demonstrated by
the applicant to be extremely remote.
or If th* nature of the pesticide Is such
that It Is approved fnr IMC on Infant*
or small children may the AdmlnUtra
tor waive this requirement
(III) 5l*lrmmf o/ pr«cfle*f fivwt
mm (-(A) TaHcitt CXeporv I A
statement of practical treatment (first
aid or other) shall appear on the frnnt
panel of the label of all peetlrldes 1*11
Ing Into Toxlclty Category I on the
basts of oral. Inhalation or dermal Inx
klty The Agerwy may. hnwever.
permit reasonable variation* In I he
placement of the statement nr prarll
-------
(conr tnued)
I let 10
(I*) The product registration.
number M prescribed In paragraph (•)
or this Mdlon.
(v) Tlit produdng establishment
number M prescribed In paragraph (I)
of this Mdlon:
(vl) An Ingredient statement M pre-
scribed In paragraph <•> ol thU MC-
Uon.
(•ID Warning or precautionary stale-
menu a* prescribed In paragraph th)
ol this Mctlon.
tvlll) The dlreetloni for use M pre-
scribed In paracraph (I) of thla section:
and
Ui) The UM classification^) as pre-
scribed In paragraph 'Pollution approved"
(g> rinul printed leorllnp (I) Fxcept
as provided In paragraph (aMtldl) of
Ihls srctlon. final printed labeling
must be submitted and accepted prior
to registration. However, final printed
labeling need not be submitted until
draft label lexis have been pro/talon-
ally accepted by the Agency
(III Clearly legible reproductions or
photo reductions will be accept *d for
unusual labrls such as those silk
screened directly onto glass or metal
containers or large bag or drum labels.
Such reproductions must be of micro-
fUm reproduction quality
(b) MIHWV brand, or trademark. (I)
The name, brand, or trademark under
whkh the pesticide product Is sold
shall appear on the front panel of the
label
(1) No name, brand, or trademark
may appear on the label whkh.
(I) Is false or misleading, or
(ID Has not bren approved by the
Admlnhlralor through registration or
siipplrmrntsl rrsUtratlon as an add!
llonal namr nnmimnl la I |S1 SihU4l
(c) Name and addrras of producer
reglntranl. or person for whom pro
duerd An unqualified name and art
drras given on Ihr latwl shsll he ron
sldrred as thr nam* and addrcwi of I he
producer If thr rrglslranl s name ap
pears on the label and Ihr registrant Is
not Ihr producer or If Ihr namr of Ihr
prraon for whom Ihr prsllrMr was
produced spprars on thr labrl II miwl
br quallflrd by appropriate wording
such as "Packed for * * * Dlnlribul
ed by • * *." or Sold by • • •' lo show
thai thr namr la no! thai of lltr pro
ducer
(dl Ntl lortp/U or mriMurr »/ ron
tent*. (I) The net wrlahl or mnuurr
of conlrnt shall br rxrhmlve of wrap
pen or other materials and ahall br
the average contrnt unlras rspllrllly
staled as a minimum quantity
(1) If the pratkldr la a liquid thr
net content alalrtnrnt shall be In
terms of liquid mramir* at •• F«1OCI
and shall be exprensrd In conventional
American units of fluid ouncra pints.
quarts, and gallons
(I) If the pntMdr Is solid or armlan
lid viscous or preasurhtrd or la a mis
lure of liquid and solid thr nrt ran
tent statement snail br In Urms nf
weight expressed as avoirdupois
pounds and ounces
(4) In all cases. n«t cnntrnt shall hr
stated In Urms of th* largrst sultablr
units. I e. "I pound It ounces * ralhrr
than "!• ounoss."
(I) In addition to thr required units
spedfled. net content may br ex
prtsstd In mstrtc unlta
(g) Variation above minimum con
Unt or around an average Is prrmUal
bis only to the extent that It repre
senls deviation unavoidable In good
manufacturing practice Variation
below a stated minimum la not prrmlt
ted In no case shall thr averagr ron
Unt of the packages In a uhlpmrnt fall
below the stated average central
(S) Product rrpOfrafln* Humor
The regUtrallon number aaalgnrd to
the pesticide product at the tlmr of
registration shall apprar on Ihr labrl
preceded by the phraae
tratlon No,- or the phra
No." The reghtratlon numl br
Ml In type of a it*e and slylffl^plr lo
other print on that part of th> lahr|
nn wtilrH It
-------
I urio
If) The label clearly show* that the
product It Intended lor use only to
manufacturing proccast* kiwi specific*
the typett) of product* Involved.
l»> Adequate Information *uch M
technical data sheet* or bulletin*, to
available to the trade specifying the
tn>e of product Involved and IU
proper use In manufacturing piocot
11M* 40—r*rot*iHosi of tsnrln
Choplar I—Cnv
>rt«l Fr«t*«tlow Afsncy
(continued)
IIMII
«-s
Ol The product will not come Into
the hands of the general public except
•fter Incorpormtlon Into finished prod-
uct*: and
<«) The Administrator determine*
lh»l nich direction* are not n«e>tsary
to prevent unreasonable adverse ef
feet* on man or the environment.
IB) Detailed direction* for u*e mar
be omitted from th* labeling of pe*U-
ctde product* for which *al* to limited
to physician*, veterlnarlam. or dnif
gist* provided that.
tl) The label clearly slate* that the
product to for u*e only by physician*
or veterinarian*:
til Th* Admlntotrator determine*
that *uch direction* are not necessary
to prevent unreasonable advene ef
feet* on man or th* environment, and
IJ> The product to ateo a drug and
regulated under the provision* of tht
Federal rood. Drug and Coametlc Act.
(C> Detailed direction* for u*e may
be omitted from th* labeling of pesll-
cMe product* whkh arc Intended for
u*e onlr by formulatort In preparing
pe*tlclde* tor aal* U th* public pro-
vided that.
tlr Th*r* to Information readily
available to the formulator* on th*
composition, toikjly. method* of uae.
applicable restriction* or limitation*.
and effectlvene** of th* product for
pectiddc purpose*;
t»> The label clearly state* that the
product to Intended for ua* only In
manufacturing, formulating, mixing,
or repacking for uae a* a peilldde and
•pcdlfrM th* trp«<*> of pesticide prod
uct* Involved.
IJ) The product a* finally manufae
lured, formulated, mixed, or repack
aged to regblered, and
(1} The AdmlnUtrator determine*
that *uch direction* are not necessary
to prevent unreasonable advene ef
feet* on man or the environment.
(II Cv4f*«f* of Direction* Aw Vtt.
The direction* tor uae «hatl Include
the following, under th* heading* ~tM
rectlon* for Use"
(I) The italement of me elaadftc*
Uon a* preacrlbed In IIJ IOIJ) hnmedl
•Uly under th* heading -Direction*
for Use "
4111 Immediately below th* *UU
mrnt of uae claMflcaUon. th* aUle-
menl -It to a violation of Federal law
to use Ihto product In a manner Incon-
•Utent with It* labeling ~
(III) Th* stle(s> of application, aa for
example the croc*, animate, areaa. or
object* to be treated.
Ov> The target pe*Us) associated
with each alte
(*l The dosage, rait ataoetated with
each alt* and peat.
of application ap-
paratus or equipment required.
Ivll> The frequency and timing of ap-
plication* necessary to obtain effective
remit* without causing unreaaonable
advene of feet* on th* environment.
(vllll Specific limitation* on reentry
to area* where th* pcsjtldd* ha* been
applied, meeting th* reqohoment*
concerning; reentry provided by 4*-
CTR Part 119
tls) Specific direction* concerning
the storage and disposal of In* peatl
tide and It* container, meeting th* re-
quirement* of <• CTR Part If I The**
Instruction* shall b* grouped and
appear under th* heading "Storage
and Dtopoaal - Thto heading moat b*
a*t In typ* of tho aam* minimum slat*
a* required for th* child hasard warn-
ing (Be* Table hi I l4S.lwthNI)4rv> »
(*> Any limitations or rwtrfcUo.4 on
uae required to prevent unreasonabl*
•dven* *f feet*, ruch aK
(A) Required Interval* between ap-
plication and harveat ef food, or feed
crop*.
4B> Rotational crop rwtrtctlona.
(C> Wamln** at required agalnH «*•
on certain crop*, animal*, object*, or
In or adjacent to certain areaa.
For restricted na* petUcMe*. a
ttaUment that the pe*Mdde may b*
applied under th* direct •upervtolon of
a certified applicator who to not phra
really present at the tit* of application
but nonrlhrleat available to thr
penon Applying the pettlclde, unle*a
the Agency ha* determined that the
pcntlcMe may only be appll-d under
the direct niprrvfailon of a err tilled ap-
plicator who to physically prrirnL
(PI Other pertinent Information
whkh the AdmlnUtralor d« Urmlne*
to be necewuiry for the protection of
m«n and the environment
(j) Stattmml of tltf Oau l/lcafton.
By October M ing. all pettklde prod-
uct* rniut bear on their btbeto a »tate
ment of inr clamlflratlon as described
InpanutrapMOKllandOlof this nee
tlnn Any pmtlrMe product for Which
some lute* are elauillled Inr general ime
and other* for restricted une *hall be
separately labeled according to the la
brllni ttandardi set forth In thb sub-
leetlon and shall be marketed as sepa
nle products with different re*lstra
tlon number*, one bearing direction*
only for general utettl and the other
bearing directions for mtrktrd useltl
except that. If a product has both re-
ttrkted u»r and *eneral iisdt) both
of these uses may appear on a product
labeled tor restricted use Such prod-
uct* shsll be subject to the provision*
of | HI I classified restricted shall
bear statement* of restricted use elas-
slIk*tlon on th* front panel as de-
scribed below
III rroHf swarf ttutrmmt o} mlrltt-
t4 are cl*M(/lc*floit. r*H «ia* rv*. • l*7*|
rfTetU.
I Criteria for fuMsnr* n/ J
fo Drsjp Jt«vt*f ratio*
VrafloM. or to Hold • llr
ipflosi. (I)
til
•umptl
Intent
•ectlon
Intent to
to section
notice of In
determln*
•hould b*
proprlal*. thsll
termination by
th* pestldd* m
th* criteria for
graph (aMl> of
de terminal
•hall latu*
the appl
may b* k
registrant^
•ubmlt
arise
registration |
of
I
bMI>
rebuttak
Uce of
tant to
notice of
regtalralVh pursuant
Act. or a
a hearing to
registration
denied, a* ap-
upon a de
dmlnlstralor that
or exceeds any of
forth In para
Ion. Upon such
Administrator
lied mall to
it, as the case
llcant or
regbtraV
that
the
Mcne* m rebult
preturn*
m
rdance
graph/SiMO of this section.'
cant sV registrant shall hate
tlll/ay* from the dale tuch
to submit evidence hi rebutl
presumption, provided, hoi
Hat for good cause shown the A<<
trator may grant an additional i
-------
11M.10
eal treatment b gome reference «uch
M "See *taUment of practical treat.
menl on back puiel' appear* on the
front panel near the word "Pobon"
and the ikull and cro**bone*
(B) OOur loxieUy eaUoorle*. The
•taUment of practical treatment b not
required on the front panel except M
described In paragraph (hXIMIIIKAl of
thb Mellon. The applicant mar. how-
ever. Include cuch a front panel itate-
ment at hi* option Statement* of
practical treatment are. however, re-
quired ebewhere on the label In
accord with paragraph re
cautionary itatemenCf The warning*
and precautionary etatemenU a* re-
quired below chall appear together on
the label under the general heading
"Precautionary Statement*" and
under appropriate *ubheadlngg of
"Hazard to Humane and Domeatle Anl .
malt." -Environmental Haxard" and I
"Phraleal or Chemical Haurd."
(II Harare! to ftumciu end dom«t(lc
mntmmU. (A> Where a hacard eiliU to
human* or domeatle animal* precau
tlonary etatemenU are required Indl
eating the particular haaard. the
rouU4*> of eipomr* and the precau
Uon* to be taken to avoid accident.
Injury or damage The precautionary
paragraph ahall be Immediately pre-
eedod by the appropriate hacard etgnal
word.
(Bl The followliMi (able deplete typl |
eal precautionary •tatemenU. Theee
•tatemenU muet bo modified o* ex
panded to reflect *poclf to hacard*.
(III CiielroiimeMlat naterd*. Where a
hazard e«UU to non Uriel ortanlmi*
eicludlni human* and domeetle anl
mala, precautionary etatemenU are re-
quired »Ulln» the nature of the
Placard and the appropriate precau
Inlury or damage Example*
hacard *taUmenU and It '
(Unce* under whkh they
follow
(A) If • pertkide Intended for out-
door o*e contain* an active Ingredient
100 or lem Ihr ctaUment "ThU Pentl
clde I* Tonic to Wildlife- b required
IB( If a penllclde Intended for out
door UHe contain* an active Iniredlent
with a lUh acute LC» ol I ppm or In*.
the (tatemrnt ThU PMtklde I* To«k
to Fhh b required
(Cl If a pcntlclde Intended for) out
door u*c contalrw an active Iniredlent
with an avlan acute oral LD. of 100
mi/kg or lem, or a (ubacute dietary
LC. of WO ppm or lem the •UUment
"ThU Pmtlclde b Toilc to WIMIKe" b
required
(D> If either accident hblory or field
•Indie* demomlrate thai une of the
pentlrlde may rcniilt In fatality to
bird*, fbh or mammata. the italement
"ThU pe*tkld> b extremely toilc lo
wildlife (fliih)- b required
I P.) For uie* Involving foliar applied
lion lo aurlculliiral rropo forenU or
•hade tree* or for mo*q»llo abate
menl treatmenU. penlklde* tnilr lo
pollinating IruerU muni bear approprl
ate label caution*
(PI For all outdoor une* other than
aquatic application* the label miiot
bear the caullon 'Keep oul of lake*
pond* or *lream* Dn not rnnlamlnale
water by cleaning of equipment or
-------
©
lOn
mtCAUIONAUT IlklfWfNtf
MA/AMOS '0 HUU«N)
It DOMf SIC AMMAIS)
0AMQIM
fNVT>ONU|NI*t. HAJAOPS
On CMtMCAl
ovwcnoNi row UM
• • . « »•*••* b» » M*
i »• > i « n •> •
«t fM1NV SIAttUIHf
STOnAGE AND
DISPOSAL
cm*
RESTRICTED USE
PESTICIDE
, fir rtltll ill* I* «•>! lit »«»r kr CtrtlMt< *r>Hi«»tr«t«U* 1*4 »»lr '•'
IHtlt (til t*ttri4 If Ikt C*rllMr« *rrl>c«Uri ttrllfl.
CtlUn. .
PRODUCT
NAME
10000%
tHA MOOUCf CONtAMS IM O» MN OM1OM
KEEP OUT OF REACH OF CHILDREN
DANGER —POISON
•f«lf MfNI Of r* AC I CO*. IfllATUtNT
9 ON «••« '
r
3f I SOt
wroi**
MClCONIfNII:
ATOnUNAi r*|CAimONAMT IIAttMfNlf I
CHOP
W AMMAN r* •lAHMNf
-------
©I
©I
&
i
©
i|C*u*O>i»n«
ti>|*nut lO»ni
ll UOM(SI< ••«
9
e*ni ION
|»iv«in»
-------
143
PHYS/CHEM-l
PHYSICAL/CHEMICAL HAZARDS
Criteria
I. Pressurized Containers
A.
Flashpoint at or below
20'F; or if there is a
flashback at any valve
opening.
B.
Flashpoint above 20'F
and not over 80'F; or
if the flame extension
is more than 18 inches
long at a distance of
6 inches from the
valve opening.
All Other Pressurized
Containers
II. Non-Pressurized Containers
A. Flashpoint at or below
20'F.
B. Flashpoint above 20'F
and not over 80'F.
C. Flashpoint over 80'F
and not over 150'F.
D. Flashpoint above
150'F.
Required Label Statement
Extremely flammable.
Contents under pressure.
Keep away from fire, sparks,
and heated surfaces. Do not
puncture or incinerate
container. Exposure to
temperatures above 13 0'F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame. Do
not puncture or incinerate
container. Exposure to
temperatures above 130'F
may cause bursting.
Contents under pressure.
Do not use or store near
heat or open flame. Do not
puncture or incinerate
container. Exposure to
temperatures above 130'F
may cause bursting.
Extremely flammable. Keep
away from fire, sparks, and
heated surfaces.
Flammable. Keep away from
heat and open flame.
Do not use or store near
heat and open flame.
None required.
-------
144
STOR-l
STORAGE INSTRUCTIONS FOR PESTICIDES
Heading:
All products are required to bear specific label instructions
about storage and disposal. Storage and disposal instructions
must be grouped together in the directions for use portion of
the label under the heading STORAGE AND DISPOSAL. Products
intended solely for domestic use need not include the heading
"STORAGE AND DISPOSAL."
Storage Instructions;
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed.
Each registrant must develop his own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, heat, sunlight,
friction, or contaminating substances or media.
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
while opening or closing container.
4. Instructions on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been
spilled, and precautions to minimize exposure if damage occurs,
5. General precautions concerning locked storage, storage in
original container only, and separation of pesticides
during storage to prevent cross-contamination of other
pesticides, fertilizer, food, and feed.
6. General storage instructions for household products should
emphasize storage in original container and placement in
locked storage areas.
-------
145
PEST/DIS-l
PESTICIDE DISPOSAL INSTRUCTIONS
The label of all products, except those intended solely for domestic
use, must bear explicit instructions about pesticide disposal. The
statanents listed below contain the exact wording that must appear on
the label of these products:
1. The labels of all products, except domestic use, must contain the
statement, "CD not contaminate water, food, or feed by storage or disposal."
2. Except those products intended solely for domestic use, the labels
of all products that contain active ingredients that are Acute Hazardous
Hastes (see list in this Appendix) or are assigned to Toxicity Category
I on the basis of oral or dermal toxicity, skin or eye irritation potential,
or Toxicity Category I or II on the basis of acute inhalation toxicity
must bear the following pesticide disposal statement:
"Pesticide wastes are acutely hazardous. Improper disposal of
excess pesticide, spray mixture, or rinsate is a violation of Federal
Law. If these wastes cannot be disposed of by use according to
label instructions, contact your State Pesticide or Environmental
Control Agency, or the Hazardous Waste representative at the nearest
EPA Regional Office for guidance."
3. The labels of all products, except those intended for domestic use,
containing active or inert ingredients that are Toxic Hazardous Wastes
(see list in this Appendix) or meet any of the criteria in 40 CFR 261,
Subpart C for a hazardous waste must bear the following pesticide disposal
statement:
-"Pesticide wastes are toxic. Improper disposal of excess pesticide,
spray mixture, or rinsate is a violation of Federal Law. If these
wastes cannot be disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control Agency, or the
Hazardous Waste representative at the nearest EPA Regional Office
for guidance."
4. Labels for all other products, except those intended for.domestic
use, must bear the following pesticide disposal statement:
"Wastes resulting fron the use of this product may be disposed of on
site or at an approved waste disposal facility."
5. Products intended for domestic use only must bear the following
disposal statement: "Securely wrap original container in several layers
of newspaper and discard in trash.*
-------
146
PEST/DIS-2
PESTICIDE ACTIVE INGREDIENTS THAT ARE ACUTE HAZARDOUS WASTES
I. PESTICIDES ON THE "E" LIST
[40 CFR 261.33(6)]
(with RCRA # and CAS *
Acrolein
Aldicarb
Aldrin
Allyl alcohol
Aluminum phosphide
4-Aminopyndine (Avitrol)
Arsenic acid
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroaniline
Cyanides (soluble cyanide salts
not otherwise specified)
Cyanogen chloride
Dieldrin
0,0-Diethyl S-[2-ethylthio)ethyl]
phosphorodithioate (disulfoton)
0,0-Diethyl 0-pyrazinyl
phosphorothioate (Zinophos\)
Dimethoate
0,0-Dimethy1 0-p-nitrophenyl
phosphorothioate (methyl parathion)
4,6-Dinitro-o-cresol and salts
4,6-Dinitro-o-cyclohexylphenol
Dinoseb
Endosulfan
Endothall
Endrin
Famphur
Fluoroacetamide
Heptachlor
Hexachlorohexahydro-exo, exo-
dimethanonaphthalene (Isodrin)
Hydrocyanic acid
Methomyl
alpha-Naphthylthic-urea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide
(OMPA, schradan)
Parathion
Phenylmercurie acetate (PMA)
Phorate
Potassium cyanide
Propargyl alcohol
Sodium azide
Sodium cyanide
Sodium fluoroacetate
P003
P070
P004
POOS
P006
POOS
P010
P011
P012
P021
P022
P024
P030
P031
P037
P039
P040
107-13-1
116-06-3
309-00-2
107-18-6
1302-45-0
504-24-5
7778-39-4
1303-28-2
1327-53-3
592-01-8
75-15-0
106-47-8
506-77-4
60-57-1
298-04-4
297-97-2
P044
P071
P047
P034
P020
P050
P088
P051
P097
P057
P059
P069
P063
P066
P072
P075
P085
P089
P092
P094
P098
P102
P105
P106
P058
60-51-5
298-00-0
534-52-1
131-89-5
88-85-7
115-29-7
129-67-9
72-20-8
52-85-7
640-19-7
76-48-8
465-73-6
74-90-8
16752-77-5
86-88-41
54-11-5
152-16-9
56-38-2
62-38-4
298-02-2
151-50-8
107-19-7
26628-22-8
143-33-9
62-74-8
-------
147
PEST/DIS-3
Strychnine and salts P108
0,0,0,0-Tetraethyl P109
dithiopyrophosphate (sulfotepp)
Tetraethyl pyrophosphate Pill
Thallium sulfate P115
Thiofanox P045
Toxaphene P123
Warfarin (>0.3%) P001
Zinc phosphide (>10%) P122
57-24-9
60-41-3
3689-24-5
107-49-3
7446-18-6
39196-18-4
8001-35-2
81-81-2
1314-84-7
50 ACTIVES
F027
F027
F027
F027
F027
5324-22-1
35109-57-0
136-25-4
327-98-0
70-30-4
II. PESTICIDES DERIVED FROM TRI-, TETRA-, AND PENTACHLOROPHENOLS
[40 CFR 261.31]
2-Chloroethyl 2-(2,4,6-trichloro-
phenoxy) ethyl ether
Dehydroabi ety1ammonium
pentachlorophenoxide
Erbon
0-ethyl 0-(2,4,5-trichlorophenyl)
ethylphosphonothioate
2,2'-Methylenebis
(3,4,6-trichlorophenol)
(Hexachlorophene)
—Potassium salt of
—Sodium salt of
—Disodium salt of
Pentachlorophenol
—Potassium salt of
—Sodium salt of
—Zinc salt of
—Zinc salt of N-alkyl
(C.g-C.8)-1,3-propanediamine
—PentacHIorophenyl laurate
Potassium trichlorophenate (2,4,6)
Potassium trichlorophenate (2,4,5)
Silvex
—2-Butoxyethyl ester
—Butoxypolypropoxypropyl ester
—Butoxypropyl ester
—Diethanolamine salt
—Diisopropanolamine salt
—Dimethylamine salt
—Dipropylene glycol isobutyl
ether ester
—Ethanolamine salt
—2-Ethylhexyl ester
—Isooctyl ester
F027 67923-62-0
F027 3247-34-5
F027 5736-15-2
F027 87-86-5
F027 7778-73-6
F027 131-52-2
F027 2917-32-0
F027
F027 3772-94-9
F027 2591-21-1
F027 .35471-43-3
F027 93-72-1
F027 19398-13-1
F027 53404-07-2
F027 25537-26-2
F027 51170-59-3
F027 53404-09-4
F027 55617-85-1
F027 53535-26-5
F027 7374-47-2
F027 53404-76-5
F027 53404-14-1
-------
148
PEST/DIS-4
—Isopropanolamine salt
—Monohydroxylaluminum salt
—Polypropoxypropyl ester
—Potassium salt
—Propylene glycol isobutyl
ether ester
—Sodium salt
—Triethanolamine salt
—Triethylamine salt
—Triisopropanolamine salt
—Tripropylene glycol isobutyl
ether ester
Sodium 2-(2,4,5-trichlorophenoxy)
ethyl sulfate
Tetrachlorophenols
—Alkylamine*amine salt (as in
fatty acids of coconut oil)
—Potassium salt
—Sodium salt
2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
2,4,5-Trichlorophenol salt of
2,6-bis[(dimethylamino)methyl]
cyclohexanone
2,4,5-Trichlorophenol, sodium salt
2,4,6-Trichlorophenol, sodium salt
2,4,5-Trichlorophenoxyacetic acid
—Alkyl C-12 amine salt
—Alkyl C-13 amine salt
—Alkyl C-14 amine salt
—N,N-diethylethanolamine salt
—Dimethylamine salt
—N,N-dimethyllinoleylamine salt
~N, N-dimethyloleylamine salt
—N-oleyl-1,3-propylene
diamine salt
—Sodium salt
—Triethanolamine salt
—Triethylamine salt
—Alkyl (C3H7 - C7H9) ester
—Amyl ester
—Butoxyethoxypropyl ester
—2-Butoxyethyl ester
—Butoxypropyl ester
—Butyl ester
—Dipropylene glycol isobutyl
ether ester
—2-Ethylhexyl ester
—Isobutyl ester
F027 53404-13-0
F027 69622-82-8
F027 83562-66-7
F027 2818-16-8
F027 53466-84-5
F027 37913-89-6
F027 17369-89-0
F027 53404-74-3
F027 53404-75-4
F027 53535-30-1
F027 3570-61-4
F027 25167-83-3
F027
F027 53535-27-6
F027 25567-55-9
F027 95-95-4
F027 88-06-2
F027 53404-83-4
F027 136-32-3
F027 3784-03-0
F027 93-79-8
F027 53404-84-5
F027 53404-85-6
F027 53535-37-8
F027 53404-86-7
F027 6369-97-7
F027 53404-88-9
F027 53404-89-0
F027 "53404-87-8
F027 13560-99-1
-F027 3813-14-7
F027 2008-46-0
F027
F027 120-39-8
F027 1928-58-1
F027 2545-59-7
F027 1928-48-9
F027 93-79-8
F027 53535-31-2
F027 1928-47-8
F027 4938-72-1
-------
149
PEST/DIS-5
—Isopropyl ester F027 93-78-7
—Propylene glycol isobutyl F027 53466-86-7
ether ester
—Tripropylene glycol isobutyl F027 53535-32-3
ether ester
4-(2,4,5-Tnchlorophenoxy)butyric F027 93-80-1
acid [2,4,5-TB]
2-(2,4,5-Trichlorophenoxy)ethyl F027 69633-04-1
hydrogen sulfate [2,4,5-TES]
1,4',5'-Trichloro-2'-(2,4,5- F027 69462-14-2
trichlorophenoxy)
- methanesulfonanilide [Edolan U] - -
-------
1 50 PEST/DIS-6
PESTICIDES THAT ARE TOXIC HAZARDOUS WASTES
PESTICIDES ON THE "F" LIST
[40 CFR 261.33(f)]
(with RCRA I. and CAS »
Acetone U002
Acrylonitrile* U009
Amitrole U011
Benzene* U019
Bis(2-ethylhexyl)phthalate U028
Cacodylic acid U136
Carbon tetrachloride* 0211
Chloral (hydrate) U034
(chloroacetaldehyde)
Chlordane, technical* U036
Chlorobenzene* U037
4-Chloro-m-cresol U039
•Chloroform* U044
o-Chlorophenol U048
Creosote U051
Cresylic acid (cresols)* U052
Cyclohexane U056
Cyclohexanone U057
Decachlorooctahydro-1,3,4-metheno- U142
2H-cyclobuta[c,d]-pentalen-2-one
(Kepone, chlordecone)
l,2-Dibromo-3-chloropropane (DBCP) U066
Dibutyl phthalate U069
S-2,3-(Dichloroallyl diisopropyl- U062
thiocarbamate) (diallate,Avadex)
o-Dichlorobenzene* U070
p-Dichlorobenzene* U072
Dichlorodifluoromethane U075
(Freon 12\)
3,5-Dichloro-N-(1,1-dimethyl-2- U192
propynyl) benzamide
(pronamide, Kerb\)
Dichloro diphenyl dichloroethane U060
(DDD)
Dichloro diphenyl trichloroethane U061
(DDT)
Dichloroethyl ether U025
2,4-Dichlorophenoxyacetic, U2 4 0
salts and esters (2,4-D)*
1,2-Dichloropropane U083
1,3-Dichloropropene (Telone) U084
Dimethyl phthalate U102
Epichlorohydrin U041
(l-chloro-2,3-epoxypropane)
Ethyl acetate U112
Ethyl 4,4'-dichlorobenzilate U038
(chlorobenzilate)
67-64-1
107-13-1
61-82-5
71-43-2
117-81-7
75-60-5
56-23-5
302-17-0
57-74-9
108-90-7
59-50-7
67-66-3
95-57-8
8021-39-4
1319-77-3
110-82-7
108-94-1
143-50-0
96-12-8
84-74-2
2303-16-4
95-50-1
106-46-7
75-71-8
23950-58-5
72-54-8
50-29-3
1191-17-9
94-75-7
8003-19-8
542-75-6
131-11-3
106-89-8
141-78-6
510-15-6
*Proposed for deletion by TCLP proposal
-------
151
PEST/DIS-7
Ethylene dibromide (EDB)
Ethylene dichloride*
Ethylene oxide
Formaldehyde
Furfural
Hexachlorobenzene*
Hexachlorocyclopentadiene
Hexachloroethane*
Hydrofluoric acid
Isobutyl alcohol*
Lead acetate
Lindane*
Maleic hydrazide
Mercury
Methoxychlor*
Methyl alcohol (methanol)
Methyl bromide
Methyl chloride
2,2'-Methylenebis
(3,4,6-trichlorophenol)
(hexachlorophene)
[acute waste per 261.31]
Methylene chloride*
Methyl ethyl ketone*
4-Methyl-2-pentanone
(methyl isobutyl ketone)
Naphthalene
Nitrobenzene*
p-Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentachlorophenol*
[acute waste per 261.31]
Phenol*
Pyridine*
Resorcinol
Safrole
Selenium disulfide
Silvex [acute waste per 261.31]
1,1,2,2-Tetrachloroethane*
Tetrachloroethylene*
2,3,4,6-Tetrachlorophenol*
[acute waste per 261.31]
Thiram
Toluene*
1,1,1-Trichloroethane*
(methyl chloroform)
Tnchloroethylene*
Trichloromonofluoromethane
(Freon 11\)
2,4,5-Trichlorophenol*
[acute waste per 261.31]
2,4,6-Trichlorophenol*
[acute waste per 261.31]
U067
U077
U115
U122
U125
U127
U130
U131
U134
U140
U144
U129
U148
U151
U247
U154
U029
U045
U132
106-93-4
107-06-2
75-21-8
50-00-0
98-01-1
118-74-1
77-47-4
67-72-1
7664-39-3
78-83-1
301-04-2
58-89-9
123-33-1
7439-97-6
72-43-5
67-56-1
74-83-9
74-87-3
70-30-4
U080
U159
U161
U165
U169
U170
U184
U185
U242
U188
U196
U201
U203
U205
U233
U209
U210
U212
U244
U220
U226
U228
U121
U230
U231
75-09-2
78-93-3
108-10-1
91-20-3
98-95-3
100-02-7
76-01-7
82-68-8
87-86-5
108-95-2
110-86-1
108-46-3
94-59-7
7488-56-4
93-72-1
79-34-5
127-18-4
~
137-26-8
108-88-3
71-55-6
79-01-6
75-69-4
95-95-4
88-06-2
-------
152
PEST/DIS-8
2, 4,5-Trichlorophenoxyacetic acid • U232 93-76-5
(2,4,5-T)*
[acute waste per 261.31]
Warfarin (<0.3%) U248 81-81-2
Xylene U239 1330-20-7
Zinc phosphide (<10%) U249 1314-84-7
83 ACTIVES
-------
153
CONT/DIS-l
CONTAINER DISPOSAL INSTRUCTIONS
The label of each product must bear container disposal
instructions appropriate to the type of container.
1. Domestic use products must bear one of the following
container disposal statements:
Container Type
Statement
|Non-aerosol products
[(bottles, cans, jars)
Do not reuse container (bottle, can, jar).
Rinse thoroughly before discarding in trash.
|Non-aerosol products
I fbaas)
I
Do not reuse bag. Discard bag in trash.
|Aerosol products
| Replace cap and discard containers in
I trash. Do not incinerate or puncture.
2. All other products must bear container disposal instructions,
based on container type, listed below:
Container Type
Statement
Metal
containers
(non-aerosol)
Plastic containers
Glass containers
Fiber drums
with liners
Paper and
plastic bags
Compressed gas
cylinders
Triple rinse (or equivalent) . Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or byj
other procedures approved by state and local
authorities.
Triple rinse (or equivalent) . Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stav out of smoke.
Triple rinse (or equivalent) . Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose" of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reused*, dispose of in the same manner.
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Return empty cylinder for reuse (or
similar wordincn
** Manufacturer may replace this phrase with one indicating
whether and how fiber drum may be reused.
-------
EPA Compendium-OTr Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTH10ATE
TABLE OF CONTENTS
Site Name Page
TERRESTRIAL FOOD CROPS 3
(Agricultural Crops) 3
Alfalfa 3
Alfalfa (seed crop) 5
Almonds 5
Apple 6
Apricot 7
Artichoke 7
Barley 8
Beans 9
Beets 11
Birdsfoot Trefoil 11
Broccoli 12
Brussels Sprouts 12
Cabbage 12
Carrots 13
Cauliflower 12
Celery 13
Cherry 14
Citrus Fruits 15
Clover 3
Clover (seed crop) 5
Collards 15
Corn 16
Cotton 18
Cucumber 22
Eggplant 22
Forage Crass 23
Garlic 23
Gooseberries 24
Grapes 24
Hops 25
Kale 15
Kohlrabi - 25
Lentils 26
Lettuce 26
Melons 28
Mustard Greens 15
Nectarines 28
Oats ' 8
Onions 29
Onions, Dry 29
Onions, Dry (seed crop) 29
Pasture 29
Peach 30
Peanuts 31
Pear 31
Peas (including blackeyed peas, cowpeas, field peas, and
southern peas) 32
Issued: 11-10-83 III-053501-1
-------
1 cr
EPA Compendium df Acceptable Uses
0,0-DIXETHTL 0-p-NITROPHENYL FHOSPHOROTHIOATE
TABLE OF CONTENTS
Site Name Page
Pecan 34
Peppers • 34
Plum 30
Potato 35
Prune 30
Pumpkins 36
Rangeland (including grass (seed crop)) 36
Rutabagas 25
Rye 8
Safflower 37
Sorghum 37
Soybeans . 3d
Spinach 39
Squash 40
Strawberry 40
Sugar Beets 41
Sunflower 41
Sweet Potato 42
Tomato 42
Turnips 44
Vetch 3
Wheat 8
TERRESTRIAL NON-FOOD CROP 45
(Agricultural Crops) 45
Guayule 45
Jojoba 45
Tobacco 45
Tobacco (to be transplanted) 46
(Ornamental Plants and Forest Trees) 47
Chrysanthemum 47
Daisy " 47
Field Crown Ornamental Flowering Plants 47
Marigolds 47
Stock 47
(Noncrop, Wide Area, and General Indoor/Outdoor Treatments) 47
Forest, Nonagricultural Land, Wastelands 47
AQUATIC FOOD CROP 48
(Agricultural Crops) 48
Rice 48
FORESTRY 49
(Ornamental Plants and Forest Trees) 49
Forest and Christmas Tree Plantings (pine) 49
Issued: 11-10-83 III-053501-ii
-------
156
EPA Compendium of Acceptable Uses
C053501 0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE*
TYPE PESTICIDE: Insecticide, Acaricide, Tadpole shrimp control agent
FORMULATIONS;
Tech (80*, 83.52)
FI (252)
D (1.252, 1.52, 1.82, 22, 2.52, 3,72)
WP (152, 202, 252, 402)
Heap (2 Ib/gal)
N EC (0.5 Ib/gal, 0.75 Ib/gal, 0.99 Ib/gal, 1 Ib/gal, 1.5 Ib/gal, 1.6 lb/
gal, 2 Ib/gal, 2.85 Ib/gal, 3 Ib/gal, 4 Ib/gal, 4.2 Ib/gal, 5 Ib/gal,
6 Ib/gal, 7.2 Ib/gal, 7.5 Ib/gal, 8 Ib/gal, 15.92, 16.82, 45.622)
RTU (3 Ib/gal)
GENERAL WARNINGS AND LIMITATIONS; RESTRICTED USE PESTICIDE.
HANDLE THE CONCENTRATE ONLY WHEN WEARING THE FOLLOWING PROTECTIVE CLOTHING
AND EQUIPMENT:
Wear a protective suit of 1 or 2 pieces that covers all parts of the body
except the head, hands, and feet. Wear chemical resistant gloves, chemi-
cal resistant apron, and chemical resistant shoes, shoe coverings, or
boots. Wear goggles or a face shield. Wear a pesticide respirator ap-
proved by the National Institute for Occupational Safety and Health under
the provisions of 30 CFR part II.
If handling the concentrate with a closed system—long-sleeve shirt and
long-legged pants may be substituted for the protective suit, and the res-
pirator requirement is waived.
WEAR THE F01LOWING PROTECTIVE CLOTHING DURING APPLICATION, EQUIPMENT RE-
PAIR, EQUIPMENT CLEANING, AND DURING EARLY REENTRY TO TREATED AREAS:
Wear a protective suit of 1 or 2 pieces that covers all parts of the body
except the head, hands, and feet. Wear chemical resistant gloves and
chemical resistant boots, shoes, or shoe coverings.
During application only from a tractor vith a completely enclosed car or
aerially vith an enclosed cockpit—long-sleeve shirt and long-legged pants
may be worn in place of the above protective clothing. Chemical resistant
gloves must be available in the cab or cockpit and must be worn while
exiting. This clothing is Inadequate to protect you during equipment re-
pair, cleaning or reentry.
Workers entering treated fields within 48 hours must wear protective
clothing. Do not apply with hand equipment.
Shrimp and crabs may be killed at labeled application rates.
Do not apply where these are Important resources. Refer to labeling for
appropriate ENDANGERED SPECIES LIMITATIONS.
Bee Caution;
Methyl parathion is highly toxic to bees exposed to direct treatment or
residues on blooming crops or weeds. Do not apply methyl parathion or
allow it to drift to blooming crops or weeds if bees are visiting the
treatment area.
*Methyl Parathion
Hetacide
o,o-dimethyl 0-p-nitrophenyl thiophospate
Issued: 11-10-83 III-053501-1
Provisional Update: 9-15-86
-------
157
EPA Compendium of Acceptable Uses
0,0-DIMETHYL O-p-NITROPHENYL PHOSPHOROTH10ATE
Agricultural Crop Tolerances (other than those listed in the text)
Avocados 1.0 pptn
Blackberries 1.0 ppo
Blueberries (huckleberries) 1.0 ppm
Boyscnberries 1.0 ppo
Citrus fruits 1.0 ppo
Cranberries 1.0 ppo
Currants 1.0 ppm
Dates 1.0 ppo
Dewberries 1.0 ppo
Endive (escarole) 1«0 ppo
Figs 1.0 ppo
Filberts 0.1 ppm
Garlic 1.0 ppo
Guar beans 0.2 ppm
Guavas 1.0 ppm
Lentils 1.0 ppo
Loganberries 1.0 ppm
Mangoes 1.0 ppm
Okra 1.0 ppm
Olives 1.0 ppo
Parsley 1.0 ppa
Parsnips (vith or without tops) 1,0 ppo
Parsnip greens (alone) 1.0 ppo
Pineapple 1.0 ppm
Qiinces 1.0 ppa
Radishes (with or without tops) 1.0 ppo
Rape seed 0.2 ppm
Raspberries 1.0 ppm
Sugarcane 0.1 ppm
Sugarcane fodder 0.1 ppo
Sugarcane forage 0.1 ppo
Swiss chard 1.0 ppo
Valnuts 0.1 ppo
Youngberries 1.0 ppm
Issued: 11-10-83 III-053501-2
-------
/23001AA
/23003AA
/23010AA
ITBJADA
ERACAAA
[NASBUJ
[NASBWC
tTBCCFC
ITBCCZA
INASBXA
INASBTA
IVABAAA
ITBCCCA
IRAFAAA
CQAMARA
[LAAABA
LMOAAAA
INAGACA
[TAAAMA
Site and Pest
'158
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
TERRESTRIAL FOOD CROPS
General Warnings and Limitations; Do not plant any food or feed crop in
methyl parathion treated soil other than those with registered methyl
parathion uses. Unless otherwise specified, apply for thorough coverage
of crop-plants. Apply when damaging or potentially damaging infestations
of the pest appear, continue at 7 day intervals as needed. Formulations
requiring dilution, unless otherwise specified, apply in sufficient water
for thorough coverage. May be applied by aircraft.
For armyvorm on vegetable and field crops, labeling claims control is ef-
fective only up to third instar.
(Agricultural Crops)
Alfalfa
Clover
Vetch
Alfalfa cater-
pillar
Aphids (including
spotted alfalfa
aphid)
Alfalfa weevil
(adults)
Alfalfa weevil
(larvae)
Armyvorm (larvae)
Climbing cutworms
Clover leaf weevil
Egyptian alfalfa
weevil
Grasshoppers
Green cloverworm
Leafhoppers
Lygus bugs
Mites (including
spider mites)
Thrips
Vetch bruchids
Webworms
AND MAI
0.234-1.25
Ib/A
(2-2.5* D)
(25-40Z WP)
(4-8 Ib/gal
EC)
(45.62Z EC)
—OR MAI—
[W/PARATHI-
ON]
0.094-1.25
Ib/A
(2-4 Ib/gal
EC)
1.25 ppm (alfalfa (fresh))
5 ppm (alfalfa hay)
1 ppm (clover, vetch)
15 day preharvest interval through
1 pound per acre for foliar appli-
cation.
20 day preharvest interval through
1.25 pounds per acre for foliar ap-
plication.
Do not apply when temperatures are
below 70 F (21.1 C).
Foliar application.
Alfalfa weevil larvae-apply when 75
percent of the terminals show feed-
ing damage or when larvae count
equals 25 larvae per sweep.
Spotted alfalfa aphid-apply 0.25 to
0.5 pound per acre in the early
spring.
In CA and NV apply 0.094 to 0.375.
pound per acre for alfalfa weevil
larvae.
OR MAI
Formulated with parathion.
Issued: 11-10-83
III-053501-3
-------
INBGAAA
ITBCABA
INAMADA
IMAAAEA
IQAQAAA
/23001AA
ITBJADA
INASBWC
ITBMBUA
ITBCCFA
ITBCCOA
INAMADA
INBPAZA
IRAFAAA
IRAEAAA
IRACFGA
INASBWC
/23001AA
/23003AA
ITBJADA
IRACAAA
ITBCCFA
IVABAAA
IRAFAAA
IMOAAAA
ITAAAMA
Site and Pest
159
EPA Compendium of Acceptable Uses
0,0-DIHETHYL 0-p-NTTROPHENTL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Alfalfa cluster (continued)
Pest list continued from previous page.
Blister beetles
Cutworms
Flea beetles
Leafrollers
Stink bugs
(Alfalfa)
Alfalfa caterpillar
Alfalfa weevil
(larvae)
Alfalfa webworm
Armyworm
Fall armyworm
Flea beetles
Japanese beetle
Leafhoppers
Spittlebug
Alfalfa weevil
complex
Pea aphid
Blue alfalfa aphid
Alfalfa weevil
(larvae)
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
Foliar application.
Formulated with methoxychlor.
0.5 Ib/A
(2 Ib/gal
Heap)
0.375 Ib/A
(2 Ib/gal
Heap)
Foliar application.
during bloom.
Do not apply
Use limited to AZ and CA.
Foliar application. Do not apply
during bloom.
0.195 Ib/A Foliar application. Apply when
(5 Ib/gal EC) buds and shoots appear ragged or
larvae count equals 15 Tarvae per
sweep.
(Alfalfa)
(Clover)
Alfalfa caterpillar
Aphlds
Armyworm
Grasshoppers
Leafhoppers
Thrips
Webworms
[W/CARBARTL] Foliar application.
0.125-0.188
Ib/A
(1.251 D)
Formulated with carbaryl.
Issued: 11-10-83
III-053501-4
-------
/23001BA
/23003BA
ISAQAFA
ISAQAFA
/23001BA
IRACAAA
ITBCCFC
IRAFAAA
IQAMARA
ILAAABA
/03001AA
ITDBAGA
ILAAABB
RAKBPA
ITAMABA
IRAKBYA
ITAUADA
IRACAAA
IMAAAEA
ITBUCJA
IRAAABA
ILAVAAA
160
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Alfalfa (seed crop)
Clover (seed crop)
Dosages and Tolerance, Use, Limitations
Formulation(s)
1.25 ppm (alfalfa (fresh))
5 ppm (alfalfa hay)
1 ppm (clover)
Do not feed treated forage to dairy
animals or animals being finished
for slaughter.
Alfalfa seed chal- 0.25-1.25 Foliar application to seed crop.
cid lb/A OR MAX
Clover seed chalcid (4-7.5 Ib/gal Formulated with parathion.
EC)
—OR MAI—
[W/PARATHI-
ON]
0.188-0.375
lb/A
(3 Ib/gal EC)
(Alfalfa (seed crop))
Aphids
Armyworm (larvae)
Leafhoppers
Lygus bugs
Kites
Almonds
Fruittree leaf-
roller
Mites (eggs)
Parlatoria scale
Peach twig borer
San Jose scale
Tent caterpillars
AND MAI
Aphids
Leafrollers
Oriental fruit moth
Scales
Spider mites
fW/ENDOSUL- Foliar application to seed crop.
FAN] Formulated with endosulfan.
0.5-1.25 lb/A
(1.5-2 Ib/gal
EC)
0.1 (N) ppm (almonds)
3.0 ppm (almond hulls)
Do not apply after hulls open
through 6 pounds per acre.
0.5-1 lb/. Dormant and delayed dormant appli-
100 gal cation. May be tank mixed with
[max 600 dormant oils.
gal/A] OR MAI
(4 Ib/gal EC) Formulated with parathion.
Scales-tank mix with dormant oils.
—OR MAI—
[W/PARA-
THION]
0.125-0.25
lb/100 gal
(3 Ib/gal EC)
Issued: 11-10-83
III-053501-5
-------
/04001AA
IRA CAM
ITBOCSA
ILAVASA
INASAVA
ITBDCJA
ITBDAPA
DUAABA
ITBUDHA
ISBEARA
ITBUAGA
IVABAAA
PAZA
tRAWAAA
TTBUALA
ILAVAAA
ITBUCSA
[NASAVA
LRAKMA
ILAVASA
Site and Pest
Apple
161
EFA Compendium of Acceptable Uses
0,0-DDffiTHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation^)
1 ppm
14 day preharvest interval through
6 pounds per acre for foliar appli-
cation.
Do not apply to Co it land, Mclntosh
and related varieties as fruit or
foliage injury may occur.
Aphids
Codling moth
European red mite
Plum curcullo
Oriental fruit moth
Redbanded leaf-
roller
Scales
AND MAI
Eyespotted bud moth
European apple
sawfly
Fruittree leaf-
roller
Grasshoppers
Japanese beetle
Leafhoppers
Leafminers
Mealybugs
Orange tortrix
Spider mites
Codling moth
Plum curcullo
San Jose scale
European red mite
0.25-0.5 lb/
100 gal
(25-402 WP)
or
0.25-1 lb/
100 gal
(4-8 Ib/gal
EC)
—OR MAI—
[W/EPN]
4-5 Ib/A
[60-800 gal/
A]
(3 Ib/gal EC)
or
[W/PARATHI-
ON] '
0.094-0.5 lb/
100 gal
(3-4 Ib/gal
EC)
0.25-0.5 lb/
100 gal
or
1-2 Ib/A
[concen-
trate]
(2 Ib/gal
Heap)
Foliar application.
Codling moth, plum eurculio,
and
redbanded leafroller-apply at petal
fall.Make 3 to 4 applications at
7 to 14 day intervals.
OR MAI
Formulated with EPN or parathlon.
Eyespotted bud moth-delayed dormant
application.
Foliar application. DB not tank
mix with streptomycin.
San Jose scale-use limited to the
Northwest.
Apply the maximum dosage for plum
cureulio and for heavy infestations
of codling moth and San Jose scale.
0.125-0.5 lb/ Foliar application. Make 2 applica-
100 gal tions at 5 day intervals. Apply
(4-8 Ib/gal during prebloom if control is not
EC) achieved during a regular spray pro-
gram.
Issued: 11-10-83
III-053501-6
-------
/C5001AA
EUCAAA
ILAVASA
roucsA
ITBTOHA
ITSDAGA
II3DCJA
IT1MABA
IT3UALA
/13018AA
RACAAA
17301AA
IT3LABA
IT3CABA
r.AMADA
RAF AM
ILAAABA
ICAMAAA
Site and Pest
Apricot
162
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
1 ppm
14 day preharvest interval through
0.25 pound per hundred gallons of
water or 2.5 pounds per acre for
foliar application.
0.117-0.25
lb/100 gal
or
0.625-2.5
Ib/A
(4-7.5 Ib/gal
EC)
Aphids
European red mite
AND MAI
Codling moth
Eyespotted bud
moth
Fruittree leaf-
roller
Oriental fruit moth —OR MAI—
Peach twig borer
Orange tortrix [W/PARATHI-
ON]
0.094-0.25/
100 gal
(3 Ib/gal EC)
Foliar application.
European red mite-make 2 applica-
tions at 5 day Intervals.
OR MAI
Formulated with parathlon.
Artichoke
Aphids
Armyworm (larvae)
Artichoke plume
moth
Cutworms (including
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Mites
Plant bugs
0.47-1 Ib/A
(25-40Z WP)
(4-8 Ib/gal
EC)
(43.622 EC)
—OR MAI—
[W/PARATHI-
ON]
0.3-1 Ib/A
(2-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.25-1 Ib/A
(2.51 D)
or
(15Z WP)
(1-2 Ib/gal
EC)
1 ppm
7 day preharvest interval through 1
pound per acre for foliar applica-
tion.
•i
Foliar application.
Apply 1 pound per acre for artichoke
plume moth and cutworms. If plants
are cut in April and May begin ap-
plications for artichoke plume moth
after September!Repeat at 14 to
21 day intervals as needed through
December.
Apply at 30 day intervals in
January and February and 14 day
intervals from March through the
end of the picking season.
OR MAI
Formulated with parathlon or endo-
sulfan.
Issued: 11-10-83
III-053501-7
-------
/24001AA
/24003AA
/24005AA
/24007AA
RACAAA
ITBCCFC
D'OCAHA
IQAMAJA
ITBCCZA
IQALAEA
IQALAHA
IVABAAA
IRAFAAA
IQAMARA
•UQAEA
•iVAAA
IQAQAAA
ILAMABA
INBGAAA
ITBCABA
ITBCCOA
IBCCFA
ITBCABA
IVABAAA
Site and Pest
163,
EPA Compendium of Acceptable Uses
0,0-DIMETHTL 0-p-NITROPHENYL PHOSPHOROTH10ATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.5 ppm (rye (interim))
1.0 ppm (barley, oats, wheat)
No preharvest interval through 0.25
pound per acre for foliar applica-
tion.
15 day preharvest interval through
0.75 pound per acre for foliar
application.
Do not apply after heads form
through 1.25 pounds per acre for
foliar application.
Aphids
Annyvorm (larvae)
Barley thrips
Black grass bug
Climbing cutworms
Chinch bug
False clinch bug
Grasshoppers
Leafhoppers
Lygus bugs
Say stink bug
Spider mites (in-
cluding brown
wheat mite)
Stink bugs
Winter grain mite
AND MAI
Blister beetles
Cutworms
Fall armyworm
Armyworm
Cutworms
Grasshoppers
0.117-1.25
Ib/A
(2-2.52 D)
(25-40Z WP)
(1.5-8 lb/
gal EC)
(43.621 EC)
—OR MAI—
[W/PARATHI-
ON1
0.094-0.5
Ib/A
(3-4 Ib/gal
EC)
[W/TOXA-
PHENE]
0.16-1.25
Ib/A
(3-4 Ib/gal
EC)
Foliar application.
Apply 0.75 pound per acre for chinch
bug, false chinch bug, and Say stink
bug (emulsifiable concentrate).
Dosages 0.117 through 1.25 pound
per acre may be applied for aphids,
black grass bug, (emulsifiable con-
centrate).
OR MAI
Formulated with parathion.
Foliar application. Sale, distri-
bution, or use of toxaphene is per-
mitted only after a showing of
emergency conditions to the Envi-
ronmental Protection Agency by a
federal or state agency and issuance
by the Environmental Protection
Agency of a finding that an emer-
gency condition exists, and only as
permitted by that Environmental
Protection Agency finding.
Formulated with toxaphene.
Issued: 11-10-83
III-053501-8
-------
Site and Pest
164
EPA Compendium of Acceptable Uses
0,0-DIMETHn. 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
/24007AA
IVABAAA
IRACADNA
/15025AA
IRACAAA
ITBCCFC
INASARA
ITS CAB A
INAMADA
IRAFAAA
IMAAAGA
INAPAFA
ILAAABA
IQAMAAA
IQAQAAA
INASARA
TTBCAWA
ITASAEA
ITBCBOA
INAMACA
cluster (continued)
(Wheat)
Grasshoppers
Greenbug
0.5 Ib/A
(2 Ib/gal
Heap)
0.25-0.375
Ib/A
(2 Ib/gal
Heap)
Beans
Aphids
Annyworm (larvae)
Covpea curculio
Cutworms (including
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Leafminers
Mexican bean beetle
Mites
Plant bugs (includ-
ing lygus bugs)
Stink bugs
AND MAI
Bean leaf beetle
Bean leafskeleton-
izer
Bean leafroller
Corn earwonn
Cucumber beetles
Foliar application.
0.88-1 Ib/A
(2-5Z D)
or
0.75-1.5 Ib/A
(25-40% WP)
or
0.31-1.5 Ib/A
(4-8 Ib/gal
EC)
(43.622 EC)
—OR MAI—
fW/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
1 ppm
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication (green beans and lima
beans).
15 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication (dry beans).
21 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication (green beans and lima
beans).
Do not apply microencapsulated
formulations to snap beans after
pods begin to form.
Foliar application.
Apply 0.94 through 1.5 pounds per
acre for cowpea eureulio, cutworms,
and BtinkTugs (emulsffiable con-
centrate) .
OR MAI
Formulated with methoxychlor,
EPN, carbaryl, parathion, or endo-
sulfan.
Issued: 11-10-83
III-053501-9
-------
165 .
EPA Compendium of Acceptable Uses
0,0-DMETHYL O-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Beans (continued)
Pest list continued from previous page.
INBDAAA
IVABAAA
INBPA2A
IHAAAEA
ITBMBFA
INAGADA
IHDAAAA
ITBCATA
ITAAAMA
IRABAAA
Darkling beetles
Grasshoppers
Japanese beetle
Leafrollers
Limabean pod borer
Pea weevil
Thrips
Velvet bean cater-
piller
Webvorms
Whiteflies
[W/EPN]
0.475-1.5
Ib/A
(2.85-4 lb/
gal EC)
or
[W/CARBARYL]
0.125-1 Ib/A
(1.25-2.5* D)
or
[W/PARATHI-
ON]
0.094-1.5
Ib/A
(2-4 Ib/gal
EC)
or
0.22 Ib/A
(3.71 D)
or
0.2 Ib/A
(20Z WP)
or
[W/ENDOSUL-
FAN]
1 Ib/A
(25* D)
or
0.45-1 Ib/A
(152 WP)
or
0.25-1 Ib/A
(1-2 Ib/gal
EC)
INAPAPA
Mexican bean beetle 0.5 Ib/A
(2 Ib/gal
Mcap)
Use limited to the southeastern
United States.
Foliar application.
Issued: 11-10-83
111-053501-10
-------
/28002AA
IRACAAA
ITBCCFC
ITBCCSA
DJAMADA
IRAFAAA
IMAAAGA
ILAAABA
IQAMAAA
IQAQAAA
INBCAAA
EN AS CCA
ITAAAMA
Site and Pest
Beets
/23011AA
166
EPA Compendium of Acceptable Uses
0,0-DIMETHYL O-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(3)
1 ppm (beets (with or without tops))
(beet greens (alone))
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication (roots).
21 day preharvest interval through
1 pound per acre for foliar appli-
cation (roots and tops).
Aphids
Annywonn (larvae)
Cabbage looper
Flea beetles
Leafhoppers
Leafminers
Mites
Plant bugs (includ-
ing lygus bugs)
Stink bugs
AND MAI
Blister beetles
Vegetable weevils
Webworms
Birdsfoot Trefoil
0.63 Ib/A
(2.5Z D)
or
0.5-1 Ib/A
(25-402 WP)
0.44-1 Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI--
[W/PARATHI-
ON]
0.125-1 Ib/A
(2-4 Ib/gal
EC)
Foliar application.
Apply 1 pound per acre for cabbage
looper, plant bugs, and stink bugs
(emulsifiable concentrate).
OR MAI
Formulated with parathion.
1.25 ppm (forage)
5.0 ppm (hay)
This use occurs only on Intrastate
labeling and has not bee*n summarized
in this entry. Refer to appropriate
labeling for use information and
limitations.
Issued: 11-10-83
III-053501-11
-------
/13005AA
/13006AA
/13007AA
/13008AA
IRACAAA
ITBCCFA
ITBCCSA
INAMADA
ITBJAHA
IRAFAAA
DtAAAGA
ILAAABA
IQAMAAA
IQAQAAA
JMOAAAA
CCZA
WBMBHA
ITCHACA
INASCCA
Site and Pest
Broccoli
167
EFA Compendium of Acceptable Uses
0,0-DBETHYL 0-p-NHROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Brussels Sprouts
Cabbage
Cauliflower
Aphids
Arnyworm (larvae)
Cabbage looper
Flea beetles
Imported cabbage
worm
Leafhoppers
Leafminers
Mites
Plant bugs
Stink bugs
Thrips
AND MAI
Climbing cutworms
Cross-striped
cabbageworm
Oiamondback moth
Vegetable weevil
1 ppm
7 day preharvest interval through
0.5 pound per acre for foliar ap-
plication (except cabbage).
10 day preharvest interval through
0.5 pound per acre for foliar ap-
plication (cabbage).
21 day preharvest interval through
1.5 pound per acre for foliar ap-
plication.
0.88 Ib/A Foliar application.
(2.52 D)
or Apply 0.94 through 1.5 pound per
0.75-1.5 Ib/A acre for cabbage looper, imported
(20-4031 WP) cabbageworm, and stink'bugs (enul-
or sifiable concentrate).
0.23-1.5 Ib/A OR MAI
(4-8 Ib/gal Formulated with methoxychlor, para-
EC) thlon, or endosulfan.
(43.62Z EC)
—OR MAI—
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/PARATHI-
ON]
0.094-1.5
Ib/A
(2-4 Ib/gal
EC)
or
[V7/ENDOSOL-
FAN]
1 Ib/A
(2.5Z D)
or
0.45-0.6 Ib/A
(15Z WP)
or
0.25-1 Ib/A
(1-2 Ib/gal
EC)
Issued- 11-10-83
111-053501-12
-------
/13005AA
INAMADA
ITBCCFA
ITBCBOA
/13005AA
/13007AA
/13008AA
IRACAAA
ITBJAHA
/14003AA
/13002AA
IRACAAA
ITBCCFC
tTBCCSA
CTBCABA
INAMADA
IRAFAAA
D1AAACA
ILAAABA
IQAMAAA
IQAQAAA
INBGAAA
ITBMCQA
ITBHAFA
Site and Pest
168
EPA Compendium of Acceptable Uses
0,0-DBIETHYL O-p-NITROPHENYL PHOSPHOROTH10ATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Broccoli cluster (continued)
(Broccoli)
Flea beetles
Armyworm
Corn earvorm
(Broccoli)
(Cabbage)
(Cauliflower)
Aphlds
Imported cabbage-
worm
Brussels Sprouts
Cabbage
Carrots
Celery
[W/CARBARYL] Foliar application.
0.5 Ib/A Formulated with carbaryl.
(22 D)
[W/CARBARYL]
1 Ib/A
(22 D)
[V/BACILLUS Foliar application.
THURING1EN- Formulated with bacillus thuringi-
SIS] ensis.
0.87-1 Ib/A
(22 D)
See Broccoli cluster.
See Broccoli cluster.
1 ppm
15 day preharvest interval through
1 pound per acre for foliar appli-
cation (carrot roots and celery).
20 day preharvest interval through
1 pound per acre for foliar appli-
cation (carrot tops).
Aphids
Armyworm (larvae)
Cabbage looper
Cutworms (Including
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Leafminers
Mites
Plant bugs (includ-
ing lygus bugs)
Stink bugs
AND MAI
Blister beetles
Celery leaftiers
Celeryworms
0.63 Ib/A
(2.52 D)
or
0.5-1 Ib/A
(25-402 WP)
0.44-1 Ib/A
(4-8 Ib/gal
EC)
(43.622 EC)
—OR MAI—
[W/PARATHI-
ON]
0.22 Ib/A
(3.7Z D)
or
Foliar application.
Apply 1 pound per acre for cabbage
looper, cutworms, plant bugs, and
stink bugs (emulsifiable coneen-
trate).
OR MAI
Formulated with parathion or endo-
sulfan.
Issued: 11-10-83
111-053501-13
-------
DIOAAAA
DJASCCA
ITAAAMA
/14003AA
RAFAAA
'05002AA
3.ACAAA
ILAVASA
ITANABA
ITAGAAA
IOAPABA
ITBUDHA
ITAAANA
IXAAAGA
IMAAAEA
ITBUCLA
r_AAABA
ITBUCJA
ITBUAYA
'iASAVA
Site and Pest
169
EPA Compendium of Acceptable Uses
0,0-DDETHTL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Dset Limitations
Formulatiop(s)
Carrots cluster (continued)
Pest list continued from previous page.
Thrips
Vegetable weevil
Webvorms
(Carrot a)
Leafhoppers
Cauliflower
Celery
Cherry
0.15-0.2
Ib/A
(20-25* WP)
or
[W/ENDOSUL-
FAN]
0.5-1 Ib/A
(2.5Z D)
or
0.25-0.666
Ib/A
(15Z WP)
(1-2 Ib/gal
EC)
[W/METHOXY- Foliar application.
CHLOR] Formulated with methoxychlor.
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
See Broccoli cluster.
See Carrots cluster.
1 ppm
15 day preharvest interval through
0.5 pound per 100 gallons of water
or 2.5 pounds per acre.
Aphlds
European red mite
AND MAI
Cankerwoms
Casebearers
Drosophila
Eyespotted bud moth EC)
Fruitworm
Leaf miners —OR MAI—
Leafrollers
Lesser appleworn fW/PARATHI-
Mites ON]
Oriental fruit moth 0.125 lb/100
Pandemis moths gal
Plum curculio (3 Ib/gal EC)
0.125-0.5 lb/ Foliar application. Repeat at 7 to
100 gal 10 day intervals.
or OR MAI
0.625-2.5 Formulated with parathion.
Ib/A
(4-7.5 Ib/gal
Issued: 11-10-83
111-053501-14
-------
INBPADA
INASABA
ERAAABG
IHBOBQA
IMOAAAA
/02000AA
/13009AA
/13011AA
/13021AA
IRACAAA
ITBCCFC
ITBCCSA
INAMADA
ITBJAGA
IRAFAAA
IMAAAGA
ILAAABA
IQAMAAA
IQAQAAA
IMOAAAA
ITBCABA
ITCHACA
IOACAHA
INASCCA
Site and Pest
17Q
EPA Compendium of Acceptable Uses
0,0-DBETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
Cherry (continued)
Pest list continued from previous page.
Hose chafer
Savflies
Scale (crawlers)
Shothole borer
Thrips
Clover
Citrus Fruits
Collards
Kale
Mustard Greens
Aphids
Armyworm (larvae)
Cabbage looper
Flea beetles
Imported cabbage-
worm
Leafhoppers
Leafminers
Mites
Plant bugs
Stink bugs
Thrips
AND MAI
Cutworms
Diamond back moth
Seed corn maggot
Vegetable weevil
See Alfalfa cluster.
0.75-1 Ib/A
(25-40Z WP)
or
0.23-1.5 Ib/A
(4-8 Ib/gal
EC)
(43.622 EC)
—OR MAI—
[W/PARATHI-
ONJ
0.22 Ib/A
(3.7Z D)
or
0.25 Ib/A
(20Z HP)
or
1 ppm
This use occurs only on Intrastate
labeling and has not been summarized
in this entry. Refer to appropriate
labeling for use information and
limitations.
1.0 ppm
0.2 ppm (mustard seed)
10 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
21 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication.
Foliar application.
Apply 0.94 through 1.5 pound per
acre for cabbage looper, imported
cabbageworm, stink bugj, and thrips
(emulsifiable concentrate).
Apply 1.5 pounds per acre for plant
bugs (emulsifiable concentrate;.
OR MAI
Formulated with parathion or endo-
sulfan.
Issued: 11-10-83
111-053501-15
-------
Site and Pest
171.
EPA Compendium of Acceptable Uses
0,0-DMZTHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
/13009AA
/13011AA
fcfcMADA
/28005AA
IRACAAA
ITBCCPC
INAMBHJ
ITBCCZA
ITBMCCA
ITBCCOA
INAMADA
IVABAAA
ILAAABA
IQAQAAA
IZZZADA
CBOA
Collards cluster (continued)
(Collards)
(Kale)
Flea beetle
Corn
0.094-1.5
Ib/A
(2-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.75 Ib/A
(2.52 D)
or
0.45 Ib/A
(15Z WP)
or
0.375-0.5
Ib/A
(1-2 Ib/gal
EC)
[W/METHOXY- Foliar application.
CHLOR] Formulated with methoxychlor.
0.25-0.5 Ib/A
(0.5-1 Ib/gal
EC)
1 ppm (corn)
(corn, forage)
12 day preharvest interval through
1 pound per acre for foliar appli-
cation.
Aphids (including
corn let; aphid)
Armyvorm (larvae)
Corn rootworms
(adults)
Climbing cutworm*
European corn borer
Fall aroyvorm
Flea beetles
Grasshoppers
Mites
Stink bugs
AND MAI
Budvorms
Corn earworm
Corn silk flies
Issued: 11-10-83
0.188-0.5 Foliar application.
Ib/A
(25-4OZ WP) Apply 0.5 pound per
Apply 0.5 pound per acre for Euro-
or pean corn borer (vettable powder).
0.23-0.51 Apply 0.23 through 0.51 pound per
Ib/A acre for grasshoppers (eraulsifiable
(4-8 Ib/gal concentrate).
EC) OR MAI
(43.622 EC) Formulated with methoxychlor, EPN,
or carbaryl, or parathion.
111-053501-16
-------
172
EPA Compendium of Acceptable Uses
0,0-DIKETHYL 0-p-NITROPHEm PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Fonnulatlon(s)
Corn (continued)
Pest list continued from previous page.
ITBCABA
INBPAZA
INBJAAA
ITBMAYA
Cutworms
Japanese beetle
Sap beetles
Southwestern corn
borer
ITBCCTA
ITBCABA
CVABAAA
Armyworm
Cutworms
Grasshoppers
—OR 11AI—
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/EPN]
0.18-1 Ib/A
(2.85-4 lb/
gal EC)
or
[W/CARBARYL]
0.125-0.25
Ib/A
(1.25Z D)
or
[W/PARATHI-
ON]
0.11 Ib/A
(3.72 D)
or
0.094-0.28
Ib/A
(2-3 Ib/gal
EC)
[W/TOXA-
PHENE]
0.75-1 Ib/A
(3-4 Ib/gal
EC)
Foliar application. Sale, distri-
bution, or use of toxaphene is per-
mitted only after a showing of
emergency conditions to the Envi-
ronmental Protection Agency by a
federal or state agency and issuance
by the Environmental Protection
Agency of a finding that an emer-
gency condition exists, and only as
permitted by that Environmental
Protection Agency finding.
Formulated with toxaphene.
Issued: 11-10-83
111-053501-17
-------
/15005AA
ITBCBOA
ITBMCCA
/28007AA
IRACAAA
ITBCCFC
ITBCBOA
UvASAHA
ITBCCSA
ITBCAOA
ITAYAHA
ITBCABA
ITBCCOA
IQALAHA
ISAMADA
IOAMBDA
I7BMBVA
UABAAA
TP.AFAAA
IXAAAEA
Site and Pest
173
EPA Compendium ot Acceptable Uses
0,0-DlMETHYL 0-p-NITROPHENTL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Corn (continued)
(Corn, Sweet)
Corn earvorm
European corn borer
Cotton
Aphids
Armywonn (larvae)
Bollworm
Boll weevil
Cabbage looper
Cotton leafworm
Cotton leafper-
forator
Cutworms
Fall armyworm
False chinch bug
Flea beetles
Fleahoppers
Garden webworm
Grasshoppers
Leafhoppers
Le^frollers
Lygus bugs
0.5 Ib/A
or
1 Ib/A
(2 Ib/gal
Heap)
0.25-1.5 Ib/A
(2-51 D)
or
0.188-1 Ib/A
(25-40Z WP)
or
0.125-3 Ib/A
(1.5-8 Ib/gal
EC)
—OR MAI—
[W/ENDRIN]
0.125-0.5
Ib/A
(1.52-2 lb/
gal EC)
or
Foliar application. Begin applica-
tions at silking. Apply 0.5 pound
per acre at 1 to 2 day intervals
and 1 pound per acre at 2 to 5 day
intervals.
0. 75 ppm (cottonseed)
No preharvest interval through 1.5
pounds per acre (dusts) or 1 pound
per acre (other formulations) for
foliar application.
7 day preharvest Interval through 3
pounds per acre for foliar applica-
tion. The above preharvest inter-
vals are limited to fields harvested
with mechanical pickers.
5 day handpicking interval through
1.5 pounds per acre (dusts) and 1
pound per acre (other formulations)
for foliar application.
Repeated applications of methyl
parathlon, particularly if made
during the early and mid seasons
may delay the maturity of cotton,
reduce the yield of cotton, and may
intensify infestations of cotton
bo11worms by suppression of its
parasites and predators.
Foliar application.
Early season; Hake 1 to 3 applica-
tions at the 2 to 4 leaf stage.
Repeat at 7 to 10 day intervals.
Apply 0.125 to 0.5 pound per acre
for aphlds, fleahoppers and thrips
when populatlons reach damaging
levels.
Mid-Seasont Apply 0.5 to 1 pound
per acre for overwintering boll
weevils. Make first application at
the start of squaring or after 10
to 25 percent of the first squares
are punctured. Repeat at 3 to 8
day intervals until tops of bolls
are full grown.
Major Fruiting Season and Periods
of heavy boll weevil migration;
Issued; 11-10-83
111-053501-18
-------
174
EPA Compendium of Acceptable Uses
0,0-DDffiTHTL O-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
ILAAABA
ITAMAOA
IQAMACA
ITABACA
IQAQAAA
IQAMATA
IMOAAAA
ITBRAKA
INBUAAA
IOABADA
ITAAAKA
Cotton (continued)
Pest list continued from previous page.
Mites (including
spider mites)
Pink bollworm
Rapid plant bug
Saltmarsh cater-
pillar
Stink bugs
Tarnished plant bug
Thrips
Tobacco budvorm
AND MAI
Darkling beetles
Serpentine leaf-
miner complex
Webworms
[W/EPN]
0.24-1 Ib/A
(2.85-4 lb/
gal EC)
or
[W/CARBARYL]
0.125-0.5
Ib/A
(1.25-2.5Z D)
or
[W/PARATHI-
ON]
0.094-3 Ib/A
(2-4 Ib/gal
EC)
or
[W/MALATHI-
ON]
0.56-0.75
Ib/A
[ulv]
(3 Ib/gal
RTU)
or
0.25-1 Ib/A
[dilute]
(4 Ib/gal EC)
or
[W/A2INPHOS
METHYL]
0.188-1.9
Ib/A
(3 Ib/gal EC)
or
[W/ENDOSDL-
FANJ
0.28-1.5 Ib/A
(152 WP)
(1.5-2 Ib/gal
EC)
or
Apply 1 to 3 pounds per acre for
boll weevil and bo11worms. Repeat
at 3 day intervals.
For control of bollworms in CA make
2 to 3 applications at 3 to 4 day
intervals. Repeat this series in 7
to 10 days until control is main-
tained. Do not sprinkle irrigate .
during the 3 to 4 day interval.
Apply in the late afternoon or
evening.
For other pests listed control is
obtained during boll weevil or boll-
worm spray programs.Otherwise
apply when damaging populations
threaten.
OR MAI
Formulated with endrin, EPN, carbar-
yl, parathion, malathion, azinphos
methyl, endosulfan, permethrin,. or
carbaryl plus parathion.
Issued: 11-10-83
111-053501-19
-------
17S
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Cotton (continued)
ITBCCFA
ITBCABA
IVABAAA
Armyworm
Cutworms
Grasshoppers
INASAHA
INBCBOA
ITBRAKA
Boll weevil (in
absence of boll-
worm)
Bollworm
Tobacco budworm
Dosages and Tolerance, Use, Limitations
Formulation(s)
[W/PERMETB-
RIN]
0.125-0.5
Ib/A
(5-6 Ib/gal
EC)
or
fW/CARBARTL
plus PARA-
THION or W/
PARATHIOK]
0.15-0.3 Ib/A
(1.5-3.72 D)
[W/TOXA-
PHENE]
0.16-1.5 Ib/A
(0.75-4 lb/
gal EC)
or
[W/TOXA-
PHENE]
plus PARA-
THION]
0.25-0.375
Ib/A
(1 Ib/gal EC)
or
[W/TOXA-
PHENE plus
MALATHION]
0.84-1.125
Ib/A
(2.25 Ib/gal
EC)
0.75 Ib/A
(2 Ib/gal
Heap)
Foliar application. Sale, distri-
bution, or use of toxaphene is per-
mitted only after a showing of
emergency conditions to the Envi-
ronmental Protection Agency by a
federal or state agency and issuance
by the Environmental Protection
Agency of a finding that an emer-
gency condition exists, and only as
permitted by that Environmental
Protection Agency finding.
Formulated with toxaphene, toxaphene
plus parathion, or toxaphene plus
malathion.
1-1.5 Ib/A
(2 Ib/gal
Heap)
Foliar application. Apply when 10
to 25 percent of the squares are
punctured. Repeat at 5 to 7 day
intervals.
Foliar application. Apply when
numbers of larvae are expected to
be damaging. Make a second appli-
cation 3 to 5 days later.
Issued- 11-10-83
111-053501-20
-------
ITBCCNA
INASARA
ITBCBOA
ITAYAHA
ITBRAKA
INASAHA
ITBCBOA
IQAMAAA
IHOAAAA
INASAHA
ITBCBOA
ITBRAKA
tTBCBOA
ETBRAKA
176
EPA Compendium of Acceptable Uses
0,0-DIMETm 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Cotton (continued)
Beet armyworm
Boll weevil
Bollvorm
Cotton leafper-
forator
Tobacco budvorn
Boll weevil
Bollworm
Plant bugs
Thrips
Boll weevil
Bollworm
Tobacco budworm
Bollworm
Tobacco budworm
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.5-1 Ib/A Foliar application. Apply as an
(4-7.5 Ib/gal occasional spray during early and
EC) mid season with a minimum of 10
days between applications. After
boll load is set make up to 3 ap-
plications at 3 to 5 day intervals.
Tank mix with methomyl.
2-4.22 oz/A Foliar application.
(4-7.5 Ib/gal Tank mix with EPN.
EC)
0.5-0.75 Ib/A
(4-7.5 Ib/gal
EC)
1-2.34 or/A
(4-7.5 Ib/gal
EC)
0.5-1 Ib/A
(4-7.5 Ib/gal
EC)
0.5-0.75 Ib/A
(2 Ib/gal
Heap)
1 Ib/A
(4-7.5 Ib/gal
EC)
1 Ib/A
(4-7.5 Ib/gal
EC)
0.5-1 Ib/A
(4-7.5 Ib/gal
EC)
0.5-0.51 Ib/A
(4-7.5 Ib/gal
EC)
Foliar application.
Tank mix with chlordimeform.
Foliar application.
Tank mix with chlordimeform hydro-
chloride.
Foliar application.
Tank mix with chlorpyrifos.
Foliar application.
Tank mix with acephate.
Foliar application.
Tank mix with permethrin.
Foliar application.
Tank mix with EPN and chlorpyrifos.
Issued: 11-10-83
111-053501-21
-------
ITBCBOA
ITBRAKC
/10010AA
IRACAAA
ILAAABA
ITBCCFA
ITBCCZA
INAMACA
INAHADA
IRAFAAA
IKAAACA
KUABA
MAWA
GAFA
ITBQADA
IMOAAAA
/11001AA
IRACAAA
INAMADA
IRAFAAA
IMAAAGA
ILAVAAA
IMOAAAA
177 -
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Cotton (continued)
Bollworm
Tobacco budworm
(larvae)
Cucumber
Aphids
Mites (including
tvospotted spider
mite)
AMD MAI
Armyworm
Climbing cutworms
Cucumber beetles
Flea beetles
Leafhoppers
Leafminers
Melonvorm
Pickleworm
Squash bug
Squash vine borer
Thrips
Eggplant
Aphids
Flea beetles
Leafhoppers
Leafminers
Spider mites
Thrips
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.5-0.51 Ib/A Foliar application.
(4-7.5 Ib/gal Tank mix with EPN and methomyl.
EC)
1 ppm
15 day preharvest interval through
1 pound per acre for foliar applica-
tion.
Do not apply before vining.
Foliar application.
OR MAI
Formulated with methoxychlor or
parathion.
0.23-0.26
Ib/A
(4-8 Ib/gal
EC)
—OR MAI—
[W/METHOXY-
CHLORJ
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/PARATHI-
ON]
0.166 Ib/A
(3.7X D)
or
0.2 Ib/A
(20Z WP)
or
0.125-0.25
Ib/A
(3 Ib/gal EC)
1 ppm
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
[W/METHOXT- Foliar application.
CHLOR] Formulated with methoxychlor or
0.25-0.5 Ib/A parathion.
(0.5 Ib/gal
EC)
or
Issued: 11-10-83
111-053501-22
-------
1/8
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSFHOROTHIOATE
Site and Pest
Eggplant (continued)
/22000AA Forage Grass
Dosages and Tolerance, Use, Limitations
Formulation(3)
[W/PARAIHI-
ON]
0.125-0.25
Ib/A
(3 Ib/gal EC)
1 ppm (forage)
15 day preharvest/pregrazing inter-
val through 0.79 pound per acre for
foliar application.
IRACAAA Aphids
ITACAAA Armyvorm (larvae)
IQAMAJA Black grass bugs
IQALAHA False chinch bug
IVABAAA Grasshoppers
IQAMAIA Grass bugs
IRAFAAA Leafhoppers
ITBNAJA Range caterpillar
AND MAI
ITBJADA Alfalfa caterpillar
INASBWJ Alfalfa weevil
(adult)
HiASBVC Alfalfa weevil
(larvae)
INBGAAA Blister beetles
INASBXA Clover leaf weevil
ITBCABA Cutworms
INASBTC Egyptian alfalfa
weevil (larvae)
INAMADA Flea beetles
DIAAAZA Leafrollers
IQAMAEA Lygus bugs
ILAAABA Mites
IQAQAAA Stink bugs
IMOAAAA Thrips
ITBUAAA Tortricid moths
ITAAAMA Pebworms
/14007AA Garlic
0.7-0.79 Ib/A Foliar aplication.
(4-8 Ib/gal Aphids-apply 0.25 pound per acre.
EC) Range caterpillar-apply 0.5 pounds
or per acre.
0.25 Ib/A OR MAI
(4 Ib/gal EC) Formulated with carbaryl or para-
thion.
—OR MAI—
[W/CARBARTL]
0.125-0.188
Ib/A
(1.25Z D)
or
[W/PARATHI-
ON]
0.094-0.28
Ib/A
(3 Ib/gal EC)
1 ppm
This use occurs only on Special
Local Need (24-C) labeling and has
not been summarized in this entry.
Refer to appropriate labeling for
use information and limitations.
Issued: 11-10-83
IH-053501-23
-------
/01013AA
IRACAAA
ILAVAAA
/01014AA
IkCAAA
CLFAOA
ITBMATA
ILAAABA
IMOAAAA
IQAQAFA
IQALAHA
ITBDCWA
[NBPBBA
INBPAZA
IRAWAAA
ITBOAPA
Site and Pest
Gooseberries
179 ,
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
1 ppm
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
Aphids
AND MAI
Spider mites
Aphids
Grape leafhopper
Grape leaffolder
Mites
Thrips
AND MAI
Consperse stink
bug
False chinch bug
Grape berry moth
Hoplia beetle
Japanese beetle
Mealybugs
Redbanded leaf-
roller
0.117-0.5 Foliar application.
Ib/A OR MAI
(4-7.5 Ib/gal Formulated with parathion.
EC)
—OR MAI—
[W/PARATHI-
ON]
0.125-0.25
Ib/A
(3 Ib/gal EC)
1 ppm
14 day preharvest interval through
1 pound per acre for foliar appli-
cation.
0.7-0.75 Ib/A Foliar application.
(25-40Z WP)
or
1 Ib/A
(2 Ib/gal
Mcap)
0.125-1 lb/
100 gal/A
(4-8 Ib/gal
OR MAI
Formulated with EPN, carbaryl, or
parathion.
When formulated with parathion:
Foliar application or post harvest
application.
—OR MAI—
(W/EPN)
0.75 Ib/A
(3 Ib/gal EC)
or
[W/CARBARYLJ
0.5-0.75 Ib/A
(2.52 D>
or
Issued: 11-10-83
111-053501-24
-------
180
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSFHOROTHIOATZ
Site and Pest
Grapes (continued)
/08020AA
RACAAA
ITBCCFC
IRAFAAA
ILAAABA
/13012AA
'14015AA
RACAAA
ITBCCFC
ITBCCSA
T.AMADA
ITBJAHA
IRAFAAA
Aphids
Armyworm (larvae)
Leafhoppers
Mites (including
spider mites)
Rutabagas
Aphids
Annywora (larvae)
Cabbage looper
Flea beetles
Imported cabbage-
worm
Leafhoppers
Dosages and Tolerance. Use, Limitations
Formulation(s)
[W/PARATHI-
ON]
0.188-0.75
Ib/A
(3-4 Ib/gal
EC)
1 ppm
15 day preharvest interval through
1 pound per acre for foliar appli-
cation.
Foliar application.
OR MAI
Formulated with parathion.
1 Ib/A
(25-402 WP)
or
0.5-1 Ib/A
(4-8 Ib/gal
EC)
—OR MAI--
[W/PARATHI-
ON]
0.188-0.5
Ib/A
(2-3 Ib/gal
EC)
See Collards cluster.
1 ppm (kohlrabi)
(rutabagas (with or without
tops))
(rutabaga tops)
7 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
21 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication.
0.75-1.5 Ib/A Foliar application.
(25-402 WP)
or Apply 0.94 to 1.5 pounds per acre
for cabbage looper, imported cab-
bagworm,and stinE bugs (emulsTFi-
able concentrate).
Issued: 11-10-83
111-053501-25
-------
TLAAABA
IQAMAAA
IQAQAAA
ITBCCZA
ITCHACA
IMOAAAA
IHASCCA
715011AA
/13020AA
IRACAAA
ITBCCFC
ITBCCSA
DJAMADA
ITBCCSA
DIAFAAA
IMAAAGA
ILAAABA
IQAMAAA
INAMBJA
Site and Pest
181
EPA Compendium of Acceptable Uses
0,0-DIMETm 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Kohlrabi cluster (continued)
Pest list continued from previous page.
Mites
Plant bugs
Stink bugs
AND MAI
Climbing cutworms
Diamondback moth
Thrips
Vegetable weevil
Lentils
Lettuce
Aphlds
Armyworm (larvae)
Cabbage looper
Flea beetles
Imported cabbage-
worm
Leafhoppers
Leafminers
Mites
Plant bugs
AND MAI
Banded cucumber
beetle
0.47-1.5
Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI—
i
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/PARATHI-
ON]
0.094-1.5
Ib/A
(2-4 Ib/gal
EC)
Apply 1.5 pounds per acre for plant
bugs (emulsif iable concent rat ejT!
OR MAI
Formulated with methoxychlor or
parathlon.
0.63 Ib/A
(2.5Z D)
or
0.5-1 Ib/A
(25-40Z WP)
or
0.375-1 Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
or
1 ppm
This use occurs only on Special
Local Need (24-C) labeling and has
not been summarized in this entry.
Refer to appropriate labeling for
use information and limitations.
1 ppm
21 day preharvest interval through
1 pound per acre for foliar appli-
cation.
Foliar application.
Apply 1 pound per acre for cabbage
looper, and plant bugs (emulsifiable
concentrate).
OR MAI
Formulated with bacillus thuringi-
ensis, carbaryl, parathion, or en-
dosulfan.
Issued: 11-10-83
111-053501-26
-------
182
EFA Compendium of Acceptable Uses
0,0-DTMETHTL O-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Lettuce (continued)
Pest list continued from previous page.
ITBCBOA
ITCHACA
ITABACA
IQAQAAA
IMOAAAA
ITAAAMA
Corn earvorm
Diamondback moth
Saltmarsh caterpil-
lar
Stink bugs
Thrips
Vebworms
—OR MAI--
[W/BACILLDS
THURINGI-
ENSIS]
0.6 Ib/A
(2Z D)
or
[W/CARBARYL]
1 Ib/A
(2Z D)
or
[W/PARATHI-
ON]
0.11-0.22
Ib/A
(3-72 D)
or
0.2 Ib/A
(20Z WP)
or
0.094-1 Ib/A
(3-4 Ib/gal
EC)
[W/ENDOStTL-
FAN]
0.6 Ib/A
(2-57. D)
or
0.45-0.6 Ib/A
(15* WP)
or
0.375-1 Ib/A
(1-2 Ib/gal
EC)
Issued: 11-10-83
111-053501-27
-------
/10001AA
IRACAAA
ITBCCFC
ITBCCSA
IRAFAAA
ILAVAAA
IMOAAAA
/05003AA
I IBM BOA
IRACAAA
IQAAABA
ITBUDHA
lAAA
IAEA
ITBQALA
ILAAABA
ITBUCJA
ITBUAYA
ITBQAHA
ITAMABA
[NASAVA
IRAAABA
INBQBQA
niOAAAA
Site and Pest
Melons
183
EPA Compendium of Acceptable Uses
0,0-DMETHTL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
1 ppm
7 day preharvest Interval through
0.164 pound per acre for foliar ap-
plication.
Aphids
Armyvonn (larvae)
Cabbage loopers
Leafhoppers
Spider mites
Thrips
Mustard Greens
Nectarines
[W/PARATHI- Foliar application.
ON] Formulated with parathion.
0.117-0.164
Ib/A
(3 Ib/gal EC)
See Collards cluster.
1 ppm
14 day preharvest interval through
0.25 pound per 100 gallons for fol-
iar application.
American plum borer
Aphids
Catfacing insects
Eyespotted bud
moth
Grasshoppers
Leafrollers
Lesser peachtree
borer
Mites
Oriental fruit moth
Pandemis moths
Peachtree borer
Peach twig borer
Plum curculio
Scales
Shothole borer
Thrips
Oats
fW/PARATHI-
ON]
0. 094-0.25
lb/100 gal
(3 Ib/gal EC)
Foliar application.
Formulated with parathion.
See Barley cluster.
Issued: 11-10-83
111-053501-28
-------
/14011AA
DIOCAVA
IRACAAA
ILAVADA
IMAAAGA
IOACACJ
IQAQAAA
/14011AA
/14011BA
IMOCAVA
/28035AA
IRACAAA
ITBCCFC
IVABAAA
IQAQAAA
D10AAAA
IOAMAAC
Site and Pest
Onions
184
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSFHOROTHIOATZ
Dosages and Tolerance, Use, Limitations
Formulation(s)
1 ppm
15 day preharvest interval through
0. 94 pound per acre for foliar ap-
plication.
Onion thrips
AND MAI
Aphids
Brown wheat mite
Leafminer
Onion maggot
(adults)
Stink bugs
Onions, Dry
Onions, Dry (seed
crop)
Onion thrips
Pasture
Aphids
Armyworm (larvae)
Grasshoppers
Stink bugs
Thrips
0.25-0.94
Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI—
[W/PARATHI-
ON]
0.094-0.25
Ib/A
(3 Ib/gal EC)
Foliar application.
OR MAI
Formulated with parathion.
0.5 Ib/A
(2 Ib/gal
Mcap)
1 ppm
15 day preharvest interval through
0.5 pound per acre. Do not apply
when onions are blooming.
Foliar application.
1.25 ppm (alfalfa fresh, birdsfoot
trefoil forage)
5.0 ppm (alfalfa hay, birdsfoot
trefoil hay)
1.0 ppm (grass, clover, vetch)
7 day preharvest/pregrezing interval
through 0.125 pound per acre for
foliar application.
15 day preharvest interval through
0. 5 pound per acre for foliar ap-
plication.
[W/CARBARYL] Foliar application.
0.125-0.188 Formulated with carbaryl.
Ib/A
(1.25Z D)
Mosquitoes (larvae) 0.063-0.125 Broadcast application to irrigated
Ib/A pastures.
(4-7.5 Ib/gal
EC)
Issued: 11-10-83
111-053501-29
-------
IVABAAA
/05004AA
/05005AA
/05006AA
185
EPA Compendium of Acceptable Uses
0,0-DIHETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Pasture (continued)
Grasshoppers
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.5 Ib/A
(2 Ib/gal
Mcap)
Foliar application.
(peaches)
(plums (fresh prunes))
14 day preharvest interval through
4 pounds per acre for foliar appli-
cation.
IRACAAA
ILAVASA
ITBUCJA
ITBQAHA
INASAVA
*
IQAAABA
ITBUAGA
IRAFAAA
IMAAAEA
•JAAA
BUALA
ITAMABA
ULAAABJ
IMOAAAA
ITAXAAA
/05004AA
ITBUCJA
INASAVA
Aphids
European red mite
Oriental fruit moth
Peachtree borer
Plum curculio
AND MAI
Catfacing Insects
Fruittree leaf-
roller
Leafhoppers
Leafroller*
Mealybugs
Mites
Orange tortrix
Peach tvig borer
Scales (crawlers)
Thrips
Tussock moths
0.5-1 lb/
100 gal
(25-402 WP)
or
0.117-1 lb/
100 gal
(4-8 Ib/gal
EC)
—OR MAI—
[W/PARATHI-
ON]
0.094-1 lb/
100 gal
(3-4 Ib/gal
EC)
Foliar application.
Oriental fruit moth and plum cyr-
culio-apply at petal fall or shuck
split. Make 3 to 4 applications at
8 to 14 day intervals.
Peach tree borer-apply to trunks
trom ground to scaffold limbs. Make
2 to 3 applications timed with moth
flight.
Apbids-apply in early cover sprays.
Aphida and European red mite-make 2
applications at 5 day intervals.
OR MAI
Formulated with parathion.
(Peach)
Oriental fruit moth 0.5 lb/100
Plum cucurlio gal
or
1.5 Ib/A
[aircraft or
concen-
trate]
(2 Ib/gal
Mcap)
Foliar application.
Issued: 11-10-83
111-053501-30
-------
/28015AA
Site and Pest
Peanuts
186
ZPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Foraulation(s)
1 ppm
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
IRACAAA
IMOAAAA
ITBCATA
ITBCBOA
IT?COOA
ERATAJA
Aphids
Thrips
Velvetbean cater-
pillar
AND MAI
Corn earvorm
Fall armyworm
Potato leafhopper
/04003AA
[TBUCSA
INASAVA
IRAiCBYA
Pear
Codling aoth
Plum curculio
San Jose scale
IRACAAA
OAVASA
[TBUCSA
ETBCBSA
IMAAAGA
Aphids
European red mite
OR MAI
Codling moth
Green fruitworm
Leafminer
0.375 Ib/A
(4 Ib/gal EC)
—OR MAI—
[W/CARBARYL]
0.5 Ib/A
(2.5Z D)
or
[W/PARATHI-
ON]
0.125 Ib/A
(3 Ib/gal EC)
or
[W/COPPER
plus SUL-
FUR]
0.375-0.5
Ib/A
(22 D)
1 lb/100 gal
(25Z WP)
or
0.25-0.5 lb/
100 gal
[max 6 Ib/A]
or
1-2 Ib/A
[concen-
trate]
(2 Ib/gal
Mcap)
1 lb/100 gal
(25Z WP)
or
0.117-0.5 lb/
100 gal
or
Foliar application.
OR MAI
Formulated vith carbaryl, parathion,
or copper as metallic from cuprous
and cupric oxide plus sulfur.
1 ppm
14 day preharvest interval through
6 pounds per acre for foliar appli-
cation.
Foliar application.
Do not tank mix microencapsulated
formulation with strepfomycin. San
Jose scale-use limited to the north-
west.
Apply the maximum dosage for plum
curculio and for heavy infestations
of codling moth and San Jose scale.
Foliar application.
European red mite-make 2 applica-
tions at 5 day intervals.
OR MAI
Delayed dormant and foliar applica-
tions.
Issued: 11-10-83
111-053501-31
-------
Site and Pest
187
EPA Compendium of Acceptable Uses
0,0-DIMZTHTL 0-p-NTTROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
IMAAAEA
IRAWAAA
ILAAABA
ISBEAEA
IRAAABG
IQAMATA
ILAJAWA
Pear (continued)
Pest list continued from previous page.
Leafroller 0.625-2.5 Formulated with parathion.
Mealybugs ib/A
Mites (4-7.5 lb/
Pear psylla gal EC)
Pear sawfl?
Scales (crawlers) —OR MAI—
Tarnished plant bug
Pearleaf blister [W/PARATHI-
mlte ON)
0.094-1 lb/
100 gal
(3-4 Ib/gal
EC)
ILAVABA
ILAVBAA
IRAXALA
ILAVBBA
Clover mite
Pacific spider mite
Pear psylla
Schoene mite
Willamette mite
Pear leaf blister
mite
0.15 lb/100 Delayed dormant and foliar applica-
gal tion.
(3 Ib/gal EC) Formulated with parathion.
/28016AA
[W/PARA-
THION ]
0.094 lb/100
gal
(3 Ib/gal EC)
Peas (including blackeyed peas,
covpeas, field peas, and southern
peas)
Delayed dormant application.
Formulated with parathion.
1 ppm (peas)
(peas*, forage)
10 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
15 day preharvest interval through
1 pound per acre for foliar appli-
cation.
15 day preharvest interval through
0.5 pound per acre for foliar appli-
cation of the microencapsulated for-
mulation (forage peas only).
Do not make more than 1 application
of the microencapsulated formulation
to forage peas per year.
Issued: 11-10-83
111-053501-32
-------
1
EFA Compendium of Acceptable Uses
0,0-DIHETHTL 0-p-KITROPHENTL PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Foraulation(s)
IRA CAM
ITBCCFC
ITBCCSA
INASARA
ITSCAB A
INAMADA
IRAFAAA
INAAAGA
ILAAABA
IQAMAAA
IQAQAAA
ITBCAVA
ITBCARA
INAGADA
IMOAAAA
IRACAIA
INASDPA
INAGADA
Peas (continued)
Aphids
Annyworm (larvae)
Cabbage looper
Cowpea curculio
Cutworms (including
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Leafminers
Mites
Plant bugs (includ-
ing lygus bugs)
Stink bugs
AND MAI
Alfalfa looper
Celery looper
Pea weevil
Thrips
Pea aphid
Pea leaf weevil
Pea weevil
0.63 Ib/A
(2.5* D)
or
0.5-1 Ib/A
(25-40Z WP)
or
0.375-1 Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI—
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/PARATHI-
ON]
0.2-0.25
(3.7Z D)
(202 WP)
or
0.094-1 Ib/A
(2-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
1 Ib/A
(2.5* D)
or
0.5 Ib/A
(1 Ib/gal EC)
0.5 Ib/A
(2 Ib/gal
Mcap)
Foliar application.
Apply 1 pound per acre for cabbage
looper, cowpea curculio, cutworms,
and stink bugs (emulsiTiable concen-
trate).
OR MAI
Formulated with methoxychlor, para-
thion or endosulfan.
Foliar application. Do not apply
to Austrian winter peas during
bloom.
Pea aphid and pea weevil-for aerial
application apply in a minimum of 5
gallons of water per acre.
Issued: 11-10-83
111-053501-33
-------
/03008AA
IRACAAA
ITBCCDA
ILAAABA
ITBMAFA
INALBCA
ITBDABA
/28017AA
IRACAAA
ITBCCFC
INAMADA
ULAFAAA
IMAAACA
ILAAABA
IQAMAAA
ITBCBOA
IOBHATA
ElAXAAA
INBPAUA
IQAQAAA
IMOAAAA
Site and Pest
Pecan
189
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROFHENYL PHOSFHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm
15 day preharvest interval 0.25
pound per 100 gallons for foliar
application. Do not apply after
husks open and do not feed treated
husks to livestock.
Aphids
Fall armyvorm
Mites
Fecan leaf case-
bearer
Twig girdler
Walnut caterpiller
Peppers
Aphids
Armyvorm (larvae)
Cabbage looper
Cutworms (including
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Leafminers
Mites
Plant bugs
AND MAI
Corn earworm
Pepper maggots
Psyllids
Rose chafer
Stink bugs
Thrips
Foliar application.
Twig girdler-make 3 to 5 applica-
tions at 14 to 21 day intervals.
[W/PARATHI-
ON]
0.125-0.25
lb/100 gal
(3 Ib/gal EC) Pecan leafcase bearer-apply 0.25
pound per acre when nuts turn brown.
Formulated with parathion.
1 ppm
15 day preharvest interval through
1 ound per acre for foliar appli-
es ion.
Fol ar application.
Apply 1 pound per acre for cabbage
looper, cutworms, and plant bugs .
(emulsifiable concentrate).
OR MAI
Formulated with methoxychlor,
carbaryl, parathion, endosulfan or
carbaryl plus parathion.
0.63 Ib/A
(2.51 D)
or
0.75-1 Ib/A
(25-40Z WP)
0.375-1 Ib/A
(4-8 Ib/gal
EC)
(A3.62Z EC)
—OR MAI—
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
[W/CARBARYL]
0.5-1 Ib/A
(2-2.5Z D)
or
[W/PARATHI-
ON]
0.1-0.3 Ib/A
(3.7* D)
(202 WP)
or
Issued: 11-10-83
111-053501-34
-------
190
EPA Compendium of Acceptable Uses
0,0-DMETHYL 0-p-NITROPSENYL PHOSPHOROTHIOATE
Site and Pest
/14013AA
ElACAAA
ITBCC7C
ITBCCSA
IQALAHA
:VIAMADA
:VABAAA
IRAFAAA
IMAGAAA
ILAAABA
IQAMAAA
IQAQAQA
IQAQAAA
IMOAAAA
INBGAAA
ITAMBJA
ITBCCZA
i:,AMCFA
Peppers (continued)
Plua
Potato
Aphids
Annywonn (larvae)
Cabbage looper
False chinch bug
Flea beetles
Grasshoppers
Leafhoppers
Leafminers
Mites
Plant bugs
Shieldbaeked bugs
Stink bugs
Thrips
AND MAI
Blister beetles
Banded cucumber
beetle
Climbing cutworms
Colorado potato
beetle
Dosages and Tolerance, Dse, Limitations
Formulation(s)
0.094-1 Ib/A
(2-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.25-0.67
Ib/A
(2.52 D)
(152 WP)
(1-2 Ib/gal
EC)
or
[W/CARBARYL
plus PARA-
THION]
0.03-0.45
Ib/A
(1.52 D)
See Peach cluster.
0.1 ppm
5 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication.
0.6-1 Ib/A
(2-2.52 D)
or
0.75-1.5 Ib/A
(25-402 WP)
or
0.23-1.5 Ib/A
(4-8 Ib/gal
EC)
(43.622 EC)
—OR MAI—
[W/CARBARYL]
0.25-1 Ib/A
(2.52 D)
or
Foliar application.
Apply 1.5 pounds per acre for cab-
bage Ipoper, false chingh bug, and
plant bugs (emulsifiable concen-
trate).
OR MAI
Formulated with carbaryl, parathion,
or endosulfan.
Issued: 11-10-83
111-053501-35
-------
IQAGAEA
IRAXAHA
INAMAPA
INASCCA
IRABAAA
/10011AA
mk
PBCCFC
ITS CCS A
INAMADA
IRAFAAA
ILAVAAA
IMOAAAA
/28045AA
/22013BA
IVABAAA
Site and Pest
191 -
EPA Compendium of Acceptable Dees
0,0-D3METHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Potato (continued)
Pest list continued from previous page.
Leaffooted plant
bug
Potato poyllid
Potato tubervorm
Vegetable weevil
Whiteflies
Prune
Pumpkins
Aphid 3
Armyworm (larvae)
Cabbage looper
Flea beetles
Leafhoppers
Spider mite
Thrips
Rangeland (including
grass (seed crop))
Grasshoppers
Rutabagas
Rye
[W/PARATHI-
ON]
0.125-1.5
Ib/A
(3-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.5-1 Ib/A
(1.5-2 Ib/gal
EC)
[W/PARATHI-
ON]
0.125-0.25
Ib/A
(3 Ib/gal EC)
See Peach cluster.
1 ppm
10 day preharvest interval through
0.25 pound per acre for foliar ap-
plication.
Foliar application.
Formulated with parathion.
0.5 Ib/A
(2 Ib/gal
Heap)
1 ppm (grass)
15 day preharvest pregrazing inter-
val through 0.5 pound per acre for
foliar application.
Foliar application.
See Kohlrabi cluster.
See Barley cluster.
Issued: 11-10-83
111-053501-36
-------
/28077AA
Site and Pest
Safflower
IRA CAM
IQAMARA
Aphids
Lygus bugs
/28019AA
Sorghum
192
EPA Compendium of Acceptable Uses
0,0-DIMETHTL 0-p-NITROPHEUYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm (safflower seed)
Do not apply after flowering through
0.5 pound per acre for foliar ap-
plication.
0.25-0.5 Ib/A Foliar application.
or OR MAI
0.5 Ib/A Formulated with parathion.
(252 WP)
—OR MAI—
[W/PARATHI-
ON]
0.15-0.5 Ib/A
(2-4 Ib/gal
EC)
0.1 ppm (sorghum)
3.0 ppm (sorghum fodder)
3.0 ppm (sorghum forage)
21 day preharvest interval through
1 pound per acre for foliar appli-
cation.
Leaf injury may occur on some hy-
brids. Test spray a few rows 7
days before the boot stage. Do not
apply with wetting agents.
RACAAA
ILAAABA
IOAHAIA
ITBCCFA
ITBCBOA
IQALAHA
IVABAAA
ITBCBAA
IQAQAAA
Aphids
Mites
Sorghum midge
AND MAI
Armyworm
Corn earvorm
False chinch bug
Grasshoppers
Sorghum webworm
Stink bugs
0.313-1 Ib/A
(4-8 Ib/gal
EC)
—OR MAI—
[U/CARBARYL]
0.125-0.25
Ib/A
(1.25Z D)
or
fW/PARATHI-
ON]
0.125-0.3
Ib/A
(3.77. D)
(2-3 Ib/gal
EC)
Foliar application.
Sorghum midge-apply when 90 percent
of the heads emerge from the boot.
Make 2 applications 3*to 5 days
apart. Apply no later than the
start of bloom.
OR MAI
Formulated with carbaryl or para-
thion.
Issued: 11-10-83
111-053501-37
-------
/28023AA
IRACAAA
ITBCCFC
INAMARA
INBGAAA
ITBCCSA
ITBCCZA
ITBCBOA
ITBMBVA
IVABAAA
ITBCCCA
INAPAFA
•kVAAA
IQAQAAA
IRAS ADA
IMOAAAA
ITBCATA
ITBJADA
INAMACA
IKBPAZA
IRAFAAA
ITABACA
Site and Pest
Soybeans
193
EPA Compendium of Acceptable Uses
0,0-DTMETHYL 0-p-NTTROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm (soybeans)
1.0 ppm (soybean hay)
15 day preharvest/pregrazing inter-
val through 0.5 pound per acre for
foliar application.
20 day preharvest/pregrazing inter-
val through 1 pound per acre for
foliar application.
Do not make more than 2 applications
per growing season.
Aphids
Armyworm (larvae)
Bean leaf beetle
Blister beetles
Cabbage looper
Climbing cutworms
Corn earvorm
Garden vebvora
Grasshoppers
Green cloverworm
Mexican bean beetle
Spider mites (in-
cluding tvospotted
spider mite)
Stink bugs
Three cornered
alfalfa hopper
Thrips
Velvet bean cater-
pillar
AND MAI
Alfalfa caterpillar
Cucumber beetles
Japanese beetle
Leafhoppers
Saltmarsh caterpil-
lar
0.25-0.5 Ib/A Foliar application.
(2.5Z D)
or Apply 1 pound per acre for army-
0.5 Ib/A vorns, bean leaf beetle, corn ear-
(25-40Z WP) worm, fall armyworm, and grassho'p-
or
0.5-1 Ib/A
(2 Ib/gal
Heap)
or
0.25-1 Ib/A
(1.5-8 Ib/gal
EC)
—OR MAI—
fW/EPN]
(2.85-4 lb/
gal EC)
or
[W/CARBARYL]
0.125-0.4
0.178-1 Ib/A
Ib/A
(1.8-2.5Z D)
or
[W/PARATHI-
OH]
0.222-0.333
Ib/A
(3.72 D)
or
0.125-1 Ib/A
(2-4 Ib/gal
EC)
or
pers (emulsifiable concentrate).
OR MAI
Formulated vith EPN, carbaryl, par-
athion, azlnphos methyl, or carbaryl
plus parathion.
Issued: 11-10-83
111-053501-38
-------
194
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
/13024AA
RACAAA
ITBCCFC
ITBCCSA
ILABAHA
iTBJAHA
ERAFAAA
IMAAAGA
ILAAABA
IQAHAAA
:OACAHA
T'OAAAA
DJASCCA
ITAAAKA
Soybeans (continued)
Spinach
Aphids
Annyworm (larvae)
Cabbage looper
Crown mite
Flea beetles
Imported cabbage-
worm
Leafhoppers
Leaf miners
Mites
Plant bugs
Seed corn maggot
(in crown)
AND MAI
Thrlps
Vegetable weevil
Webworms
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
[W/A2INPHOS
METHYL]
0.56-0.94
Ib/A
(3 Ib/gal EC)
or
[W/CARBARYL
plus PARA-
THION]
0.225 Ib/A
(1.5Z D)
1 ppm
15 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
21 day preharvest interval through
1 pound per acre for foliar appli-
cation.
0.63 Ib/A
(2.51 D)
or
0.5-1 Ib/A
(25-40Z WP)
or
0.375-1 Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI—
[W/PARATHI-
ON]
0.25 Ib/A
(25Z WP)
or
0.188-1 Ib/A
(3-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.75 Ib/A
(2.5% D)
or
Foliar application.
Apply 1 pound per acre for cabbage
looper and plant bugs (emulsifiable
concentrate).
OR MAI
Formulated with parathion or endo-
sulfan.
Issued: 11-10-83
111-053501-39
-------
195
EPA Compendium of Acceptable Uses
0,0-DIMETHTL O-p-NITROPHENTL PHOSPHOROTHIOATE
Site and Pest
Spinach (continued)
/10012AA Squash
IRACAAA Aphids
ITBCCFC Armyvorm (larvae)
I IB CCS A Cabbage looper
C.AMADA Flea beetles
I2AFAAA Leaf hoppers
ILAAABA Mites
D'OAAAA Thrips
Strawberry
PACAAA Aphids
IIAAABA Mites
AND MAI
I'AHAAA Crickets
I'.AMADA Flea beetles
?AFAAA Leafhoppers
C1AAAEA Leafrollers
SAMARA Lygus bugs
IOALAJA Paraerae
D'OAAAA Thrips
Dosages and Tolerance,
Foraulation(s)
0.45 Ib/A
(15Z WP)
or
0.375-0.5
Ib/A
(1-2 Ib/gal
EC)
:, Limitation"
[W/PARATHI-
ON]
0.094-0.15
Ib/A
(3 Ib/gal EC)
1 ppo
15 day preharvest interval through
0.15 pound per acre for foliar ap-
plication.
Foliar application.
Formulated with parathion.
1 pptn
14 day preharvest interval through
0.79 pound per acre for foliar ap-
plication.
0.5-0.79 Ib/A Foliar application.
(25-40Z WP)
(4-8 Ib/gal Apply 0.75 pound per acre for
EC) mites.
OR MAI „
—OR MAI— Formulated with parathion.
[W/PARATHI-
ON]
0.125-0.375
Ib/A
(3 Ib/gal EC)
Issued: 11-10-83
111-053501-40
-------
/28020AA
IRACAAA
ITBCCFC
ITBCABA
ITBCCOA
INAMADA
IVABAAA
ZRATAAA
IMAAAGA
IQAMARA
ILAAABA
IQAQAAA
ITBMBWA
ITBCAVA
INBGAAA
IRAEAKA
ITAAAMA
/27011AA
IOBMARA
ITBMBPA
INASFPA
Site and Pest
Sugar Beets
196
EPA Compendium of Acceptable Uses
0,0-DlHETHYL 0-p-HITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm (beets, sugar)
(beets, sugar (tops))
20 day preharveat interval through
0.375 pound per acre for foliar
application (roots).
60 day preharvest interval through
0.375 pound per acre for foliar
application (tops).
Aphids
Armyworm (larvae)
Cutworms
Fall armyvorm
Flea beetles
Grasshoppers
Leafhoppers
Leafminers
Lygus bugs
Mites
Stink bugs
Sugarbeet webworm
AND MAI
Alfalfa loopers
Blister beetles
Meadow spittlebug
Webworms
Sunflower
Sunflower maggot
Sunflower moth
Sunflower seed
weevil complex
0.25-0.375
Ib/A
(25-4CK VP)
(4-8 Ib/gal
EC)
—OR MAI--
[W/PARATHI-
ON]
0.11-0.25
(3.71 D)
(2-3 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.25-0.375
Ib/A
(2 Ib/gal EC)
Foliar application.
OR MAI
Formulated with parathion or endo-
sulfan.
0.94-1 Ib/A
(4-8 Ib/gal
EC)
0.2 ppm (sunflower seed)
30 day preharvest interval through
1 pound per acre for /oliar applica-
tion. Do not make more than 3 ap-
plications at 5 day intervals per
growing season.
Do not feed seeds to birds.
Foliar application.
Apply at first flowering or at onset
of bloom. Repeat at 5 day inter-
vals.
Issued: 11-10-83
111-053501-41
-------
/14018AA
IRACAAA
ITBCCFC
ITBCCSA
ITBCABA
INAMADA
IRAFAAA
ILAAABA
/11005AA
IRACAAA
ITBCCFC
ITBCCSA
INAMADA
tRAFAAA
01AAAGA
ILAAABA
IQAMAAA
IRAXARA
INBGAAA
INAMCFA
INBUAAA
[TBCCOA
IVABAAA
ITBRAAA
[RAXAPA
IQAQAAA
I>fOAAAA
Site and Pest
Sweet PC -«to
197 -
EPA Compendium of Acceptable Uses
0,0-DIMETHYL O-p-NTTROPHENYL PHOSFHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm
5 day preharvest interval through
0.8 pound per acre for foliar ap-
plication. •
Aphids
Annyworm (larvae)
Cabbage looper
0.5-0.8 Ib/A
(25-40* WP)
or
Foliar application.
OR MAI
Formulated vith parathion.
Cutworms (including 0.75-0.79
surface feeding
and climbing cut-
worms)
Flea beetles
Leafhoppers
Mites
Tomato
Aphids
Armyworm (larvae)
Cabbage looper
Flea beetles
Leafhoppers
Leafminers
Mites
Plant "bugs
Tomato psyllid
AtlD MAI
Blister beetles
Colorado potato
beetle
Darkling beetle
Fall armyworm
Grasshoppers
Hornworms
Psyllids
Stink bugs
Thrips
Ib/A
(4-8 Ib/gal
EC)
—OR MAI—
[W/PARATHI-
ON]
0.25-0.375
Ib/A
(3 Ib/gal EC)
0.87-1 Ib/A
(2.5Z D)
or
0.75-1.5
Ib/A
(25-40Z WP)
or
0.23-1.5 Ib/A
(4-8 Ib/gal
EC)
(43.62Z EC)
—OR MAI—
[W/METHOXY-
CHLOR]
0.25-1 Ib/A
(0.5-1 Ib/gal
EC)
or
1 ppm
10 day preharvest interval through
0.5 pound per acre for foliar ap-
plication.
15 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication.
Foliar application.
Apply 0.94 to 1.5 pounds per acre
for cabbage looper (emulsifiable
concentrate).
Dust may be formulated with bacillus
thuringiensis.
OR MAI
Formulated vith methoxychlor, EPN,
parathion, endosulfan, and carbaryl
plus parathion.
Issued: 11-10-83
111-053501-42
-------
Site and Pest
198
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Tomato (continued)
Pest list continued from previous page.
ITBCBOA
IN AS CCA
IRABAAA
Tomato fruitworm
Vegetable weevil
Whiteflies
[W/EPN]
0.48-1.33
Ib/A
(2.85-4 lb/
gal EC)
or
[W/CARBARYL]
0.5-1 Ib/A
<2-2.52 D)
or
[W/PARATHI-
ON]
0.22-0.25
Ib/A
(3.72 D)
(202 WP)
or
0.125-0.47
Ib/A
(3-4 Ib/A)
or
[W/ENDOSUL-
FAN] •
1 Ib/A
(2.52 D)
or
0.3-1 Ib/A
(252 WP)
(1-2 Ib/gal
EC)
or
[W/CARBARYL
plus PARA-
THIONJ
0.3-0.45 Ib/A
(1.52 D)
Issued: 11-10-83
111-053501-43
-------
/28022AA
IRACAAA
ITBCCFC
ITBCCSA
INAMADA
ITBJAHA
IRAFAAA
IMAAAGA
INBGAAA
ITBCABA
ITCHACA
IQALAHA
IMOAAAA
INASCCA
ITAAAMA
Site and Pest
Turnips
199
EPA Compendium of Acceptable Uses
0,0-DUETHYL O-p-NTTROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Fonaulation(s)
1 ppm (turnips (with or without
tops))
(turnip greens)
7 day preharvest interval through
0.5 pound per acre for foliar ap-
plications.
15 day preharvest interval through
0.8 pound per acre for foliar ap-
plication (roots).
21 day preharvest interval through
0.8 pound per acre for foliar ap-
plication (tops).
Aphids (including
cabbage aphid)
Armyvora (larvae)
Cabbage looper
Flea beetles
Imported cabbage-
worm
Leafhoppers
Leafminers
Mites
Plant bugs
AND MAI
Blister beetles
Cutworms
Diamondback moth
False chinch bug
Thrips
Vegetable weevils
Webwonas
Vetch
Wheat
Issued:
11-10-83
0.75 lb/A
(2.52 D)
or
0.5-0.8 lb/A
(25-402 W?)
or
0.23-0.8
lb/A
(4-8 Ib/gal
EC)
—OR MAI—
[W/CARBARYL]
0.5 lb/A
(2.52 D)
or
[W/PARATHI-
ON]
0.094-0.75
lb/A
(2-4 Ib/gal
EC)
or
[W/ENDOSUL-
FAN]
0.75 lb/A
(2.52 D)
or
0.45 lb/A
(152 WP)
or
0.375 lb/A
(1 Ib/gal EC)
See Alfalfa cluster.
See Barley cluster.
111-053501-44
Foliar application.
Cabbage aphids-in the coastal areas
of CA, apply when aphids are present
and colonies abundant.
Apply 0.7 to 0.8 pound per acre for
cabbage aphids, cabbage looper,
imported cabbageworm, and plant
bugs (emulsifiable concentrate).
OR MAI
Formulated with carbaryl, parathion,
or endosulfan.
-------
Site and Pest
200
EPA Compendium of Acceptable Uses
0,0-DIKETHTL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance, Use. Limitations
Formulation(s)
726015AA
/27018AA
/26003AA
IRACAAA
ITBCBNA
ITBRARA
IRACAAA
ITBCABA
ITBCCSA
IQAQAAA
ITBCBNA
INAMBUA
ITBRAKA
IQAMAFA
TERRESTRIAL NON-FOOD CROP
(Agricultural Crops)
Guayule
Jojoba
Tobacco
Aphids
Tobacco budworm
Tobacco hornworm
1-1.5 Ib/A
(2 Ib/gal
Heap)
Aphids (including
green peach aphid)
Cutworms (Including
surface feeding
and climbing cut-
worms)
AMD MAI
Cabbage looper
Stink bugs
Tobacco budworm
Tobacco flea beetle
Tobacco hornworm
Tobacco suckfly
0.5 Ib/A
(25-402 WP)
or
0.23-0.5
Ib/A
(4-8 Ib/gal
EC)
—OR MAI—
[W/CARBARYLJ
0.18-0.375
Ib/A
(1.25-1.82 D)
or
N.F.
This use occurs only on Special
Local Need (24-C) labeling and has
not been summarized in this entry.
Refer to appropriate labeling for
use information and limitations.
N.F.
This use occurs only on Special
Local Need (24-C) labeling and has
not been summarized in this entry.
Refer to appropriate labeling for
use information and limitations.
N.F.
5 day pre-priming interval through
1.5 pounds per acre.
15 day pre-cutting interval through
1.5 pounds per acre.
Avoid contact with plant juices
when priming or cutting.
Foliar application.
Apply in 25 to 40 gallons of water
per acre.
Tobacco budworm-apply in 18 to 40
gallons of water per acre. Repeat
at 5 to 7 day intervals.
Foliar application.
Formulated with carbaryl, parathion,
endosulfan, carbaryl plus parathion,
or endosulfan plus zineb.
Issued: 11-10-83
111-053501-45
-------
201
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Tobacco (continued)
/26003DA Tobacco (to be trans-
planted)
Dosages and Tolerance, Use, Limitations
Formulation(s)
[W/PARATHI-
ON]
0.11-0.5
Ib/A
(2-3.7Z D)
or
0.094-0.375
Ib/A
(3 Ib/gal EC)
(24.06-32.7Z
EC)
or
[W/CARBARYL
plus PARA-
THION]
0.225-0.3
Ib/A
or
[W/ENDOSUL-
FAN plus
ZINEB]
0.4-0.5 Ib/A
(22 D)
N.F.
Do not apply within 5 days of
transplanting.
INBPALC Green June beetle
(larvae)
[TBCCSA Cabbage looper
LNAMADA Flea beetles
1TBRAAA Horn worms
QAQAAA Stink bugs
ETBCBNA Tobacco budworms
0.167-0.25 Application to transplant beds.
lb/100 gal/ Apply emulsifiable concentrates
100 sq.yd with a sprinkling can.-
(4-7.5 Ib/gal OR MAI
EC) Formulated with carbaryl or endo-
sulfan.
—OR MAI— With carbaryl apply with a hand
duster.
[W /CARBARYL]
0.216-0.432
or/
100 sq.yd
(1.8Z D)
or
Issued: 11-10-83
111-053501-46
-------
Site and Pest
EPA Compendium of Acceptable Uses
0,0-DIMETHYL ^-p-NITROPHENYL PHOSFHOROTHIOATE
Dosages and Tolerance, Use, Limitations
Formulation(s)
Tobacco (to be transplanted) (continued)
P/ENDOSUL-
FAN]
0.094-0.25
lb/100 gal
[1 gal/
sq.yd]
(1.5 Ib/gal
EC)
/31003AA
/31065AA
/31085AA
/31137AA
/31188AA
IRACAAA
IRABAAA
(Ornamental Plants and Forest Trees)
Field Grown Ornamental Hovering
Plants
Chrysanthemum
Daisy
Marigolds
Stock
Do not apply to Chrysanthemums be-
fore plants flower.
Aphlds
Whiteflies
[W/ENDOSUL-
FAN]
0.5-1 Ib/A
(2.52 D)
Foliar application.
Formulated with endosulfan.
(Noncrop, Wide Area, and General Indoor/Outdoor Treatments)
/67000AA
Forest, Nonagricul-
tural Land, Waste-
lands
IOAHAAC
Mosquito (larvae)
Toxic to fish and wildlife. Do not
use where shrimp and crabs are an
important resource. Do not use in
any estuaries, coastal or tidal
areas along the Southeast Atlantic
or Gulf Coast. When treating lakes
or other open bodies of water, apply
only to shallow edges. Consult
state fish and game departments be-
fore applying to public waters.
0.1-0.117 por use by Mosquito Abatement Dis-
Ib/A tricts and Official Government Agen-
(4-7.5 Ib/gal cies.
EC) Broadcast application.
Issued: 11-10-83
111-053501-47
-------
Site and Pest
203
EPA Compendium of Acceptable Uses
0,0-D1METHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Dosages and Tolerance. Use, Limitations
Formulation(s)
/28072AA
AQUATIC FOOD CROP
(Agricultural Crops)
Rice
IRACAAA
ITBCCFC
IVABAAA
IRAPAAA
IQAQAAA
Aphids
Armyvonn (larvae)
Grasshoppers
Leafhoppers
Stink bugs
ITBCCTA
ITBCABA
IVABAAA
Armyvorm
Cutworms
Grasshoppers
IVABAAA
IOARABA
ITBAABA
Grasshoppers
Rice leafminer
Tadpole shrimp
1 ppm
15 day preharvest interval through
0.79 pound per acre for foliar ap-
plication.
Do not apply within 14 days of an
application of propanil.
0.75 Ib/A
(25Z WP)
or
0.47-0.79
Ib/A
(1.5-7.5
Ib/gal EC)
—OR MAI—
fW/CARBARYL]
0.125-0.188
Ib/A
(1.25Z D)
[W/TOXA-
PHENE]
0.16-0.75
Ib/A
(2-4 Ib/gal
EC)
Foliar application.
OR MAI
Formulated with carbaryl.
0.5 Ib/A
(2 Ib/gal
Heap)
Foliar application. Sale, distri-
bution, or use of toxaphene is per-
mitted only after a showing of
emergency conditions to the Envi-
ronmental Protection Agency by a
federal or state agency, and issuance
by the Environmental Protection
Agency of a finding that an emer-
gency condition exists, and only as
permitted by that Environmental
Protection Agency finding.
Formulated with toxaphene.
Foliar application.
0.7-0.75 Ib/A use limited to CA.
(4-7.5 Ib/gal Foliar application.
EC)
Apply at first
sign of infestation following plan-
ting. Apply in 5 to 10 gallons of
water per acre by aircraft. Limit
rice spill for 3 days following ap-
plication.
Issued: 11-10-83
111-053501-48
-------
IQAQAAA
204
EPA Compendium of Acceptable Uses
0,0-DUETHTL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Rice (continued)
—OR MAI—
[W/PARATHI-
OM]
0.25 Ib/A
(3 Ib/gal EC)
Stinkbugs (includ- 0.23-0.53
ing rice stinkbug) Ib/A
(2 Ib/gal
Heap)
(4-8 Ib/gal
EC)
OR MAI
Formulated with parathion.
Foliar application.
FORESTRY
(Ornamental Plants and Forest Trees)
'30059AA Forest and Christmas Tree Plantings
'30005AA (pine)
ETBUDDA European pine shoot 0.94-1 Ib/A Foliar application. Apply in 5 to
moth (4-7.5 Ib/gal 50 gallons of water per acre.
tTBUDEA Nantucket pine tip EC)
moth
3900300
XAAAAAA
AERIAL, MOTHPROOFING AND TANK MIX APPLICATIONS
Aerial Application
Refer to
TERRESTRIAL FOOD CROPS
(Agricultural Crops)
All Sites
TERRESTRIAL NON-FOOD CROPS
(Agricultural Crops)
Tobacco
(Nonerop, Wide Area, and General Indoor/
Outdoor Treatments)
Forest, Nonagricultural Land,
Wastelands
Issued: 11-10-83
111-053501-49
-------
205
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
9001500 Tank Mix
UAAAAA
~" TERRESTRIAL FOOD CROPS
~~(Agricultural Crops)
Almonds, Cotton
Issued- 11-10-83 111-053501-50
-------
206
EPA Compendium of Acceptable Uses
0,0-DIHETHYL O-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation
&280.0001 80Z technical chemical
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
002393-00355 003125-00035 004787-00004 009618-00003
009859-00267 039511-00002
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
000476-01710 000524-00068 000524-00136
&283.5001 83.51 technical chemical
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum distillate (006601)
000876-00015
&025.0002 25% formulation intermediate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
005905-00339 037686-00065
&001.2503 1.251 dust
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus carbaryl
(056801)
000769-00339
&001.5003 1.5Z dust
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus carbaryl
(056801)
002124-00721 005905-00314 046946-00171
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), carbaryl
(056801) plus parathion (057501)
001842-00255
&001.8003 1.87. dust
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus carbaryl
(056801)
037686-00037
&002.0003 22 dust
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
001526-00450
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus bacillus
thurlngiensis var. kurstaki (006402)
001202-00270
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus carbaryl
(056801)
001202-00298 005905-00313
Issued: 11-10-83 111-053501-51
-------
207
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
2X dust (continued)
0,0-dimethyl 0-p-nitrophei 1 phosphorothloate (053501) plus parathion
(057501)
001812-00199
0,0-dimethyl 0-p-nitTophenyl phosphorothioate (053501), zineb (014506)
plus endosulfan (079401)
000279-02808
&002.5003 2.57. dust
0,0-dimethyl 0-p-nitrophenyl phosphorothloate (053501)
000476-01044 001812-00073 005905-00078 005905-00372
037686-00026
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus carbaryl
(056801)
001812-00076 001812-00208 005905-00327 006735-00110
009779-00146
0,0-dimethyl 0-p-nitrophenyl phosphorctbloate (053501) plus endosulfan
(079401)
000279-02680
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), copper as
metallic from cuprous and cupric oxide (042403) plus sulfur or sulphur
(077501)
037686-00043
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), endosulfan
(079401) plus toxaphene (080501)
000279-02966*
*currently unavailable for review
4003.7003 3.7Z dust
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus parathion
(057501)
005905-00146
&015.0006 15% wettable powder
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus endosulfan
(079401)
000279-02574
&020.0006 202 wettable powder
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus parathion
(057501)
005905-00110
Issued: 11-10-83 111-053501-52
-------
208
EPA Compendium of Acceptable Uses
0,0-DIKETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
& 025. 0006 257, wet table powder
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
000279-02669 000524-00129 001202-00161 007001-00207
&040. 0006 40Z vet table powder
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
000524-00146
&102.0009 2 Ib/gal microencapsulated
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
004581-00292 004581-00320 004581-00324
&100. 5012 0.5 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), methoxychlor
technical (034001) plus xylene range aromatic solvent (086803)
005905-00366
&100.7512 0.75 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nltrophenyl phosphorothioate (053501), malathion
(053501), toxaphene (080501) plus xylene (086802)
003743-00326
A100. 9912 0.99 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene (086802)
003743-00330
«
&101.0012 1 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), methoxychlor
technical (034001) plus xylene range aromatic solvent (086803)
005905-00367
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), endosulfan
(079401) plus xylene range aromatic solvent (086803)
000279-02609
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene (086802)
037430-00335
&101.5012 1.5 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
005905-00223
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum derivative solvent (006501) plus toxaphene (080501)
001191-00310
Issued: 11-10-83
111-053501-53
-------
209
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
1.5 Ib/gal emulslfiable concentrate (continued)
0,0-dimethyl 0-p-nltrophenyl phosphorothioate (053501), petroleum
distillate (063503) plus endosulfan (079401)
000279-02608
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), endosulfan
(079401) plus xylene (086802)
007001-00119 034704-00183
/
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene (086802)
003743-00322
S101.6012 1.6 Ib/gal emulsifiable concentrate
0,0-diraethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum derivative solvent (006501) plus endrin (041601)
009857-00107 040831-00022
&102.0012 2 Ib/gal eaulsifiable concentrate
0,0-dimethyl O—p-nitrophenyl phosphorothioate v. 53501) plus aromatic
petroleum distillate (006601)
000554-00063
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus petroleum
distillate (063503)
004185-00143
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
000264-00354 001842-00114 005905-00176 046946-00019
0,0-dimethyl 0-p-nitrophenyl phoephorothioate (053501) plus xylene
range aromatic solvent (086803)
005905-00306 005905-00344 005905-00348
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), parathion
(057501) plus xylene (086802)
001812-00139 001812-00140
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), parathion
(057501) plus xylene range aromatic solvent (086803)
000476-02014 005905-00241
0,0-dimeth, :. 0-p-nitrophenyl phosphorothioate (053501), endosulfan
(079401) f us xylene (086802)
005967-0 '^2 001226-00051 010226-00051
0,0-dimethyl 0-p-nitrcphenyl phosphorothioate (053501), endosulfan
(079401) plus xylene range aromatic solvent (086803)
000279-02149
Issued 11-10-83 111-053501-54
-------
&102.8512
&103.0012
210
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
2 Ib/gal emulsifiable concentrate (continued)
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene (086802)
001526-00479 003743-00262 003743-00299
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene range aromatic solvent (086803)
003142-00048 007467-00054
2.85 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), 0-ethyl
0-(p-nitrophenyl)phenylphosphonothioate (041801) plus xylene range
aromatic solvent (086803)
000876-00409
000876-00418
000876-00425
001339-00222
033722-00013
000352-00406
000876-00413
000876-00423
000876-00430
012062-00010
037686-00001
000876-00234
000876-00414
000876-00424
001339-00219
032928-00010
044605-00001
000876-00411
000876-00422
000876-00426
006735-00238
034704-00071
3 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus parathion
(057501)
000524-00144 001812-00154 001990-00457
002935-00360
010163-00003
019713-00083
000279-02128*
002124-00720
008934-00067
012130-0002 5
037686-00051
002393-00354
009859-00200
014475-00016
044317-00018
007401-00203
010226-00034
034704-00016
^currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic petro-
leum derivative solvent (006501) plus 0-ethyl 0-(p-nitrophenyl)phenyl-
phosphonothioate (041801)
000769-00376
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum derivative solvent (006501") plus parathion (057501)
000769-00329 009859-00108 011656-00016 040831-00105
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum derivative solvent (006501) plus malathion (057701)
009779-00207*
*currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum derivative solvent (006501) plus 0,0-dimethyl S-[(4-oxo-
1,2,3,-benzotria2in-3(4H)-yl)raethyl] phosphorodithioate (058001)
000769-00439 009779-00191*
*currently unavailable for review
Issued: 11-10-83
111-053501-55
-------
211
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
3 Ib/gal emulsifiable concentrate (continued)
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus 0-ethyl 0-(p-nitrophenyl)phenyl-
phosphonothioate (041801)
009779-00031 019713-00057 025030-00007 045115-00031*
^currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus parathion (057501)
009779-00125
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus 0,0-dimethyl S-[(4-oxo-l,2,3,-
benzotriazin-3(4H)-yl)methyl] phosphorodithioate (058001)
009779-00191
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), 0-ethyl
0-(p-nitrophenyl)phenylphosphonothioate (041801) plus xylene (086802)
001842-00256 005905-00085 012130-00010 013166-00007
044317-00030
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), 0-ethyl
0-(p-nitrophenyl)phenylphosphonothioate (041801) plus xylene range
aromatic solvent (086803)
001063-00122 002935-00349 003442-00694 004841-00065
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), parathion
(057501) plus xylene (086802)
001202-00125 001528-00487 001812-00139 005905-00225
007001-00202 008934-00080 045115-00022
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), parathion
(057501) plus xylene range aromatic solvent (086803)
000400-00232 000476-01894 000476-01989 000876-00071
001258-01025 002737-00039 003468-00018 004185-00308
005481-00152 006735-00118
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), malathion
(057701) plus xylene (086802)
005905-00242*
*currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene (086802)
000400-00263 001526-00499 003743-00323 012130-00007
034704-00027
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene range aromatic solvent (086803)
044605-00004
Issued: 11-10-83 111-053501-56
-------
*104.0012
212
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
3 Ib/gal emulsifiable concentrate (continued)
0,0-dimethyl 0-p-nitrophenyl phosphorothloate (053501), aromatic
petroleum distillate (006601), malathion (057701) plus xylene (086802)
034704-00020
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601), 0,0-dimethyl S-[(4-oxo-l,2,3,-benzotri-
azin-3(4H)-yl)methyl] phosphorodithioate (058001) plus xylene (086802)
005905-00247
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601), 0,0-dimethyl S-[(4-oxo-l,2,3,-benzotri-
azin-3(4B)-yl)methyl] phosphorodithioate (058001) plus xylene range
aromatic solvent (086803)
001258-01039*
*currently unavailable for review
4 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum derivative solvent (006501)
000524-00128 000524-00273 000769-00340 000802-00498
002269-00096
010163-00002
044684-00001
001191-00284
009859-00104
015575-00011
000524-00273
001258-01019
009859-00152
044317-00008
007401-00155
014775-00015
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum distillate (006601)
001063-00104 001339-00140 004841-00038 008648-00012
008867-00003 009779-00034 010411-00003 011656-00030
025030-00003 039190-00003
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus petroleum
distillate (063503)
003743-00298 019713-00037 042057-00071 042463-00005
045115-00046
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
000264-00353
001842-00205
002737-00019
011682-00007
033439-00003
000400-00206
002124-00745
003051-00067
012062-00005
033722-00006
001598-00182
002217-00471
005905-00055
012130-00018
039511-00092
001842-00133
002393-00246
008934-00029
013166-00011
040831-00041
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
000476-01078 000876-00069
001258-01030 001526-00194
003442-00688 004185-00256
006735-00089 007232-00002
000279-01500
001208-00034
002935-00142
004977-00107
001202-00124
001990-00370
004581-00117
007467-00059
Issued: 11-10-83
111-053501-57
-------
213
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
4 Ib/gal emulsifiable concentrate (continued)
009779-00162 010107-00039 034704-00010 037686-00029
037686-00029 044605-00002
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus 0-ethyl 0-(p-nitrophenyl)phenyl-
phosphonothioate (041801)
009779-00131 025030-00009
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus parathion (057501)
001202-00076
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus malathion (057701)
009779-00153*
*currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), 0-ethyl
0-(p-nitrophenyl)phenylphosphonothioate (041801) plus xylene (086802)
001339-00220 001842-^0268 005905-00107 006735-00154
044317-00024
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), 0-ethyl
0-(p-nitrophenyl)phenylphosphonothioate (041801) plus xylene range
aromatic solvent (086803)
003442-00691
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), malathion
(057701) plus xylene (086802)
005905-00198*
*currently unavailable for review
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), toxaphene
(080501) plus xylene range aromatic solvent (086803)
044605-00005 045639-00056
$104.2012 4.2 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum derivative solvent (006501)
00524-00131
.105.0012 5 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501)
010226-00007
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum derivative solvent (006501)
000524-00276* 010163-00007
*currently unavailable for review
Issued- ,11-10-83 111-053501-58
-------
214
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
5 Ib/gal emulsifiable concentrate (continued)
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum distillate (006601)
011656-00013
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
007001-00054
0,0-diaethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
000279-01431 000476-01518 002935-00363 005481-00175
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), xylene (086802)
plus pennethrin (109701)
005905-00465
&106.0012 6 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum derivative solvent (006501)
000524-00274 000769-00440 001339-00184
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
037686-00067
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic
petroleum distillate (006601) plus permethrin (109701)
005905-00466
&107.2012 7.2 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum distillate (006601)
009779-00218
&107.5012 7.5 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus aromatic
petroleum distillate (006601)
001339-00183 039190-00001
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
005905-00414
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
range aromatic solvent (086803)
002935-00421 004185-00452 006735-00239 007401-00301
007467-00061 034704-00072
Issued: 11-10-83 . 111-053501-59
-------
215
EPA Compendium of Acceptable Uses
0,0-DIHETm 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
IBS.0012 8 Ib/gal emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) .plus aromatic
petroleum derivative solvent (006501)
000524-00272
> 215. 9012 15.9% emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), endosulfan
(079401) plus xylene (086802)
000279-02057*
*currently unavailable for review
^216.8012 16. 8Z emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus toxaphene
(080501)
010163-00012
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), aromatic petro-
leum distillate (006601) plus toxaphene (080501)
002460-00053*
*currently unavailable for review
*245.6212 45.627 emulsifiable concentrate
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501) plus xylene
(086802)
003468-00017
PD3.0016 3 Ib/gal liquid-ready to use
0,0-dimethyl 0-p-nitrophenyl phosphorothioate (053501), malathion
(057701) plus xylene (086802)
000241-00225 003743-00321
J999999
State Label Registrations
AL Reg. No.
009779-04760
015575-05336
039297-10584
AZ Reg. No.
000279-04033
007001-04374
010026-05671
011656-05742
CA Reg. No.
000239-04134
000279-03901
002935-06668
015575-05327
015575-05338
001526-09112
007001-04375
010026-05673
011656-05752
000239-04135
000279-03997
002935-06672
015575-05328
039297-10582
002935-06659
007001-04380
010226-03758
000279-03508
000279-04015
005481-03849
015575-05331
039297-10583
002935-06660
007001-04383
011656-05724
000279-03517
001202-05028
005481-03850
Issued: 11-10-83
111-053501-60
-------
216
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Listing of Registration Numbers by Formulation (continued)
CA Reg. No. (continued)
005967-05148
006973-03603
007001-07708
007001-10565
010226-03757
010965-09874
011369-08797
011656-05694
CO Reg. No.
008773-04617
FL Reg. No.
002342-06945
035222-07164
GA Reg. No.
001812-05435
LA Reg. No.
004814-06127
MO Reg. No.
010371-07494
TX Reg. No.
004581-04480
033722-03273
037854-08624
006023-
007001-
007001-
008434-
010226-
011124-
011656-
•03038
•07672
•07711
•04728
•03764
•09000
05688
005967-06218
007001-07659
007001-07709
008434-04727
010226-03761
010972-05298
011369-08810
035296-05795
008773-04621
009859-07628 009859-07632
035222-07165 035222-07166
011017-08194
004841-06166 037841-08558
006023-03047
007001-07706
007001-07744
010226-03750
010951-09803
011124-09001
011656-05693
035222-07163
007467-03390 007467-03394 033722-03271
037854-08296 037854-08297 037854-08301
Issued: 11-10-83
111-053501-61
-------
217
EPA Compendium of Acceptable Uses
0,0-DIMETHYL 0-p-NITROPHENYL PHOSPHOROTHIOATE
Appendix A
Listing of Common Chemical Names Used on the Entry
Chemical Common Name EPA Acceptable
Code (source) Common/Chemical Name
028201 propanil (ISO) 3',4'-dichloropropionanilide
034001 methoxychlor methoxychlor, technical
041801 EPN 0-ethyl 0-(p-nitrophenyl)phenylphosphono-
thloate
042403 copper copper as metallic from cuprous and copper
oxide
058001 azinphos-methyl (ISO) 0,0-dimethyl S-[(4-oxo-l,2,3-benzotriazin-
3(4H)-yl)oethyl] phosphorodithioate
Issued- 11-10-83 111-053501-62
-------
218
BIBGUIDE-l
GUIDE TO USE OF THIS BIBLIOGRAPHY
1. CONTENT OF BIBLIOGRAPHY. This bibliography contains
citations of all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources .for studies in this
bibliography have been the body of data submitted to EPA
and its predecessor agencies in support of past regulatory
decisions. Selections from other sources including the
published literature, in those instances where they have
been considered, will be included.
2. UNITS OF ENTRY. The unit of entry in this bibliography
is called a "study." In the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
"studies" generally have a distinct title (or at least a
single subject), can stand alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study.
3. IDENTIFICATION OF ENTRIES. The entries in this bibliography
are sorted numerically by "Master Record Identifier," or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It is not related to the six-digit "Accession Number"
which has been used to identify volumes of submitted
studies; see paragraph 4(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late in the review may be preceded by a nine-character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number is
also to be used whenever specific reference is needed.
4. FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards of the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
-------
219
BIBGUIDE-2
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four-digit date is followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??), the Agency was unable to determine
or estimate the date of the document.
i
c. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets.
d. Trailing Parentheses. For studies submitted to the
Agency in the past, the trailing parentheses include
(in addition to any self-explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
"received.11
(2) Administrative Number. The next element,
immediately following the word "under," is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission.
(3) Submitter. The third element is the submitter,
following the phrase "submitted by." When
authorship is defaulted to the submitter, this
element is omitted.
(4) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA accession number of the volume
in which the original submission of the study
appears. The six-digit accession number follows
the symbol "CDL," standing for "Company Data
Library." This accession number is in turn
followed by an alphabetic suffix which shows the
relative position of the study within the volume.
For example, within accession number 123456, the
first study would be 123456-A; the second, 123456-
B; the 26th, 123456-Z; and the 27th, 123456-AA.
-------
220
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION GUIDANCE DOCUMENT BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Parathion Guidance Document
GS00153001 Shipp, O.E.; Lindquist, D.A., and J.R. Brazzel. (1963). Character-
istics of residues of methyl parathion applied in field cotton.
J. Econ. Enton. 566:793-798
GS00153002 Interegional Research Project No. 4. (1978) Results of tests on
the amount of methyl parathion residues remaining in or on
guar beans, including a description of the analytical method
used, (unpublished study dated August 3, 1978 under 8E2108)
GS00153003 Pennwalt Corp. (1984) Application for amended registration Pen-
ncap-M Microencapsulated insecticide ULV aerial application to
cotton in vegetable oil. (unpublished study received June 11,
1984 under E.P.A. Reg. No. 4581-292)
GS00153004 U.S. EPA (1983). EPA Index to Pesticide Chemicals: Methyl Parathion.
Issued Nov. 10, 1983.
GS00153005 U.S. EPA Toxicology Branch Review, Docket #000168. Roger Gardner,
July 28, 1978.
GS00153006 Bomhard, E,; Loeser, E., and B. Schilde. (1981). E 605-methyl
chronic toxcological study on rats, (unpublished study nos.
9889 and 12559 prepared by Bayer AG Institute to Toxicology,
Wuppertal, West Germany, for Cheminova, Lemvig, Denmark; dated
March 31, 1981)
GS00153007 Daly, I. (1984). A Two year chronic feeding study of methyl parathion
in rats. Project No 77-2060. Study conducted at Bio/dynanucs,
Inc., P.O. Box 43, East Millstone, N.J. 08873.
GS00153008 Machemer, L. (1977). Parathion-methyl, Evaluation for embryotoxic
and teratogenic effects on rats following oral administration.
(unpublished report no. 6825 prepared by Bayer AG Institute of
Toxicology, Wuppertal, West Germany; submitted by Cheminova,
Lemvig, Denmark)
GS00153009 Renhof, M. (1984). Parathion-methyl (Folidol M active ingredient),
Study for embryotoxic effects on rabbits after oral administration.
(unpublished report No. 12907, prepared by Bayer AG Institute
of Toxicology, Wuppertal, West Germany; submitted by Cheminova,
Lemvig, Denmark)
GS00153010 Jotz, M.; Rundle, D.; and A. Mitchell. (1980). An evaluation of muta-
genic potential of parathion-methyl employing the L5178Y TK+'~ mouse
lynphoma assay. SRI International, Project No. LSU-7558. Prepared for
EPA, Contract No. 68-02-2947.
-------
221
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION GUIDANCE DOCUMENT BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Parathion Guidance Document
GS00153011 Jones, D.; Simon, V.; Mortelmans, K.; Mitchell, A.; Evans, E.; Riccio,
E.; Robinson, D.; and B. Kirkhart. (1984). In vitro and in vivo
mutagenicity studies of environmental chemicals. U.S. Environmental
Protection Agency, Document EPA-600/1-84-003. Contract no. 68-02-2947.
GS00153012 Evans, E.; and A. Mitchell. (1980). An evaluation of the effect of para-
thion on sister chrcmatid exchange frequencies in cultured Chinese
hanster ovary cells. Submitted by SRI International. Prepared for
the U.S. Environmental Protection Agency; Contract No. 68-02-2947
(SRI Project LSU-7558). Final report dated March, 1980.
GS00153014 Hudson, R.H., Tucker, R.K., and M.A. Haegele. (1984). Handbook of toxi-
city of pesticides to wildlife. USDA Publication 153, Washington, DC.
GS00153015 Knittle, C.E. and R.H. Hudson. (1973). Final report: Pesticides
evaluation toxicity comparisons between technical methyl para-
thion and an encapsulated formulation (Penncap-M®). U.S.D.I.r
Bureau of Sport Fisheries and Wildlife, Denver Wildlife Research
Center, (unpub. report).
GS00153016 Grue, C. (1982). Response of canton grackles to dietary concentrations
of four organophosphate pesticides. Arch. Environm. Contam. Toxicol.
11: 617-626.
GS00153017 U.S. EPA. (1979). Report on the toxicity of technical methyl parathion,
99%, to albino rats. U.S. EPA, Chemical and Biological Investigations
Branch, Beltsville, MD., 5 Day Feeding Test, 13, February 2, 1979.
(unpub. report).
GS00153018 U.S. EPA. (1980). Report on the toxicity of technical methyl parathion,
99% to albino rats. (U.S. EPA, Chemical and Biological Investigations
Branch, Beltsville, MD, 5 Day Dietary Test, No. 55, February 13, 1980,
(unpublished report).
GS00153019 U.S. EPA. (1980). Study of the chemical and behavioral toxicity of
substitute chemical in microtine rodents. EPA-60013-78-082, August
1978.
GS00153020 Kendall, R., Driver, C., and L. Brewer. (1984). The effects of methyl
parathion on wild avian species in agricultural areas of Skagit
Valley, Washington. U.S. EPA, Corvallis Environmental Research
Laboratory, (unpub. report).
GS00153021 Kendall, R., Driver, C., and L. Brewer. (1985). Effects of methyl
parathion on wild avian species in agricultural areas of Skagit
Valley, Washington. U.S. EPA, Corvallis Environmental Research
Laboratory. (unpub. report).
GS00153022 U.S. EPA. (19??). Toxicity of selected controlled release and cor-
responding unformulated technical grade pesticides to the fathead
minnow (Punephales pronelas). U.S. EPA , Duluth Environmental
Research Laboratorv. (pre-pub, report).
-------
222
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION GUIDANCE DOCUMENT BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Parathion Guidance Document
GS00144012 Johnson, W.; and Finley, M. (1980) Handbook of Acute Toxicity of
Chemicals to fish and Aquatic Invertebrates. USDI Publication
137, Washington, D.C.
GS00155025 Wojeck, G.A.; Price, J.F.; Nigg, H.N. and J. H. Stamper (1983)
Worker Exposure to Paraquat and Diquat. Arch. Environ. Contam.
Toxicol. 12: 65-70.
-------
223
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00003724 Winterlin, W. (1968) Residues Found on Mustard and Rape Seed. In-
cludes undated method. (Unpublished study received Aug 11, 1972
under 3E1300; prepared by Univ. of California—Davis, Dept. of
Environmental Toxicology, submitted by Interregional Research
Project No. 4, New Brunswick, N.J.; CDL:092201-B)
00008516 E.I. du Pont de Nemours and Company (1976) Data Supporting Use of
Lannate Methcmyl Insecticide and Lannate L Methomyl Insecticide
Plus Methyl Parathion on Cotton. Summary of studies 227339-B
through 227339-M. (Unpublished study received Jul 13, 1976
under 352-342; CDL:227339-A)
00009821 Werum, L.N.; Parkins, M.; Frents, G. (1961) Request for Analysis or
Experiment: No. 14096. (Unpublished study including nos. 14097-
14099, received Aug 30, 1966 under unknown admin, no.; prepared
by California Packing Corp., submitted by FMC Corp., Philadel-
phia, Pa.; CDL:119652-A)
00009822 Thornburg, W.; Werum, L.N.; Parkins, M.; et al. (1963) Re-
quest for Analysis or Experiment: No. 21065. (Unpublished study
including nos. 03538, 16638, 16641, 16643, and 21066-21070,
received Aug 30, 1966 under unknown admin, no.; prepared by
California Packing Corp., submitted by FMC Corp., Philadelphia,
Pa.; CDL:119652-E)
00020560 Schafer, E.W. (1972) The acute oral toxicity of 369 pesticidal,
pharmaceutical and other chemicals to wild birds. Toxicology
and Applied Pharmacology 21(? ):315-330. (Also in unpublished
submission received Apr 25, 1978 under 476-2180;.submitted by
Stauffer Chemical Co., Richmond, Calif.; CDL:233577-C)
00022923 Hill, E.F.; Heath, R.G.; Spann, J.W.; et al. (1975) Lethal Dietary
Toxicities of Environmental Pollutants to Birds: Special Scien-
tific Report—Wildlife No. 191. (U.S. Dept. of the Interior,
Fish and Wildlife Service, Patuxent Wildlife Research Center;
unpublished report)
00031669 Penwalt Corporation (1977) Residue Data: Introduction: Penncap-M.
(Unpublished study received Feb 12, 1980 under 4581-EX-16; CDL:
241841-A)
00035176 Mulla, M.S.; Isaak, L.W.; Axelrod, H. (1963) Field studies on the
effects of insecticides on seme aquatic wildlife species. Jour-
nal of Economic Entomology 56(2) .-184-188. (Also in unpublished
submission received Jan 28, 1970 under 241-216; submitted by
American Cyanamid Co., Princeton, N.J.; CDL:002057-V)
-------
224'
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00035330 Orloski, E.J.; Devine, J.M.; Pass, B.C.; et al. (1969) Malathion
and Methyl parathion Residues in Alfalfa: Report No. C-217.
Includes undated method entitled: Gas chromatographic deter-
mination of Malathion and Methyl parathion residues in alfalfa
(green foliage and dry hay). (Unpublished study received Feb
19, 1970 under 241-219; prepared in cooperation with Syracuse
Univ. Research Corp., submitted by American Cyanamid Co.,
Princeton, N.J.; CDL:002059-C)
00035332 Roberts, W.W.; Waldron, A.C.; Goleman, L.; et al. (1967) Alfalfa
Residues: Methal and Ethul parathion. (Unpublished study re-
ceived Apr 1, 1969 under 241-219; prepared in cooperation with
Ohio State Univ. and Univ. of Nevada, Cooperative Extension
Service, Div. of Agricultural Biocnemistry and Pest Control,
submitted by American Cyanamid Co., Princeton, N.J.; CDL:
002059-G)
00035890 Dorough, H.W.; Randolph, N.M. (1967) Comparative Residual Nature of
certain Insecticides Applied as Low Volume Concentrate and Water
Emulsion Sprays. Bulletin of Environmental Contamination &
Toxicology 2(6):340-342. (Also in unpublished submission re-
ceived Apr 1, 1969 under 241-219; submitted by American Cyanamid
"Co., Princeton, N.J.; CDL:002059-F)
00047726 Fahey, J.E. (1961) The Results of Tests on the Amount of Residue
Remaining, Including a Description of the Analytical Method
Used: Methyl parathion. (Unpublished study received May 4,
1962 under 524-128; prepared in cooperation with U.S. Dept. of
Agriculture, submitted by Monsanto Co., Washington, D.C.; CDL:
101429-B)
»
00051649 Culver, W.H. (1975) Introduction and Summary: Penncap-M. (Un-
published study received Dec 24, 1975 under 6E1724; prepared in
cooperation with GHT Laboratories, submitted by Pennwalt Corp.,
-j.Philadelphia, Pa.; CDL:095194-A)
00053436 Pennwalt Corporation (1973) Residue Studies on Various Crops.
Includes five undated methods for Methyl parathion. (Unpub-
lished study including published data and letter dated Sep 11,
1973 from R.A. Reynolds to Gentlemen, received Jan 8, 1974 under
4581-EX-16; CDL:127286-A)
00061199 Pennwalt Corporation (1972) Disappearance of Methyl and Ethyl para-
thion on Foliage from Applications of Penncaps and E.G. Formu-
lations. (Unpublished study received Sep 29, 1980 under 4581-
292; CDL:243398-A)
-------
225
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00061213 Pennwalt Corporation (1980) Penncap-M Insecticide—Simulated
Avian Field Study: Project No. WT-12-79. (Unpublished study
received Sep 29, 1980 under 4581-292; CDL:243398-P)
00061214 Kuc, W.J. (1977) The Acute Toxicity of Penncap-M to the Blue-
gill Sunfish, Leponis macrochirus Rafinesque and Rainbow Trout,
Salmo gairdneri Richardson UCES Project # 11506-41-01. (Un-
published study received Sep 29, 1980 under 4581-292; prepared
by Union Carbide Corp., submitted by Pennwalt Corp., Philadel-
phia, Pa.; CDL:243398-R)
00066220 Atkins, E.L., Jr.; Anderson, L.D.; Kellum, D.; et al. (1976)
Protecting Honey Bees from Pesticides. ?: Univ. of California,
Div. of Agricultural Sciences. (Leaflet 2883; also in unpub-
lished submission received Mar 20, 1980 under 432-502; sub-
mitted by Penick Corp., Lyndhurst, N.J.; CDL:243536-B)
00066341 U.S. Environmental Protection Agency, Environmental Research Labo-
ratory (1981) Acephate, Aldicarb, Carbophenothion, DEF, EPN,
Ethoprop, Methyl Parathion, and Phorate: Their Acute and Chronic
Toxicity, Bioconcentration Potential, and Persistence as Related
to Marine Environments: EPA-600/4-81-023. (Unpublished study)
00072376 Pennwalt Corporation (1972) Disappearance of Methyl and Ethyl
Parathion on Foliage from Applications of Penncaps and E.G.
Formulations. (Compilation; unpublished study received Dec 4,
1980 under 4581-292; CDL:244308-A)
00072512 Tegens, A.S., Underwood, P.C. (1978) Methyl Parathion: Ninety Day
Feeding to Dogs: Report No. 7758; Report No. 77-117. (Unpub-
lished study, including submitter suimary, received May 4, 1981
under 524-68; prepared by Pharmacopathics Research Laboratories
Inc., submitted by Monsanto Co., Washington, D.C.; CDL:244991-B)
00072513 Daly, I.W.; Rinehart, W.E. (1980) A Three Month Feeding Study of
Methyl Parathion in Mice: Project No. 77-2057. (Unpublished
study, including letter, submitter summary, dated Apr 11, 1980
from T.W. Fuhremann to W.D. Carpenter, received May 4, 1981 un-
der 524-68; prepared by Bio/dynamics, Inc., submitted by Monsan-
to Co., Washington, D.C.; CDL:244995-A)
00073196 FMC Corporation (1964) Residues on Grain Sorghum. (Compilation;
unpub. study received Jan 7, 1967 under 7F0519; CDL: 090614-F)
00074299 Daly, I.W.; Rinehart, W.E. (1980) A Three Month Feeding Study of
Methyl Parathion in Rats: Project No. 77-2059. (Unpublished
study, including letter, submitter summary, dated Mar 7, 1980
from T.W. Fuhremann to W.D. Carpenter and letter dated Aug 5,
1980 from T.W. Fuhremann to W.D. Carpenter, received May 4, 1981
under 524-68; prepared by Bio/dynamics, Inc. in cooperation with
Experimental Pathology Laboratories, Inc., submitted by Monsanto
Co., Washington, D.C.; CDL:244993-A; 244994)
-------
226
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00074486 Atkins, E.L.; Kellum, D. (1980) Effect of Pesticides on Api-
culture: Maximizing the Effectiveness of Honey Bees as Polli-
nators: Project No. 1499. 1980 annual rept. (Unpublished
study received Jun 8, 1981 undeb D41-259; prepared by Univ. of
California—Riverside, Citrus Research Center and Agricultural
Experiment Station, Dept. of Entomology, submitted by American
Cyanamid Co., Princeton, N.J.; CDL:070148-G)
00076148 McCann, J.A. (1968) Methyl Parathion: Bluegill: Test No. 129.
(U.S. Agricultural Research Service, Pesticides Regulation
Div., Animal Biology Laboratory; unpublished study; CDL:
102958-A)
00080018 Monsanto Company (1981) Residues of Methyl Parathion in Ginned
Cottonseed following Postemergent Application of Methyl Para-
thion/Permethrin Tank Mixes to Cotton Fields: MSL-1669. In-
cludes undated method entitled: Analytical residue method for
methyl parathion in cottonseed and method Ran 0018 dated Jan 16,
1981. (Unpublished study received Aug 31, 1981 under 524-128;
CDL:245821-A)
00081419 Randolph, N.M.; Dorough, H.W. (1964?) Residues on Grain Sorghum
Sprayed with Dimethoate, Ethion, Azinphosmethyl and Methyl
Parathion. (Unpublished study received Jan 7, 1967 under
7F0519; submitted by FMC Corp., Middleport, N.Y.; CDL:090614-E)
00083028 Vilkas, A.G. (1977) The Acute Toxicity of Penncap-M to the
Water Flea Dapnnia magna Straus: UCES Proj. # 11506-41-01.
(Unpublished study received Dec 4, 1980 under 458-1-292; prepared
by Union Carbide Corp., submitted by Pennwalt Corp., Philadel-
phia, Pa.; CDL:244308-R)
00085259 Hercules, Incorporated (1976) Data Summary: Toxaphene and Methyl
Parathion on Sweet Corn. (Compilation; unpublished study re-
ceived Apr 15, 1976 under 891-23; CDL:223962-A)
00085260 University of Florida (1974) Analysis of Toxaphene and Methyl
Parathion Residues on Sweet Corn. (Unpublished study received
Apr 15, 1976 under 891-23; prepared by Institute of Food and
Agricultural Sciences, Dept. of Food Science, Pesticide Research
Laboratory, submitted by Hercules, Inc., Agricultural Chemicals,
Wilmington, Del.; CDL:233962-C)
00085261 Weischedel, B.C. (1976) Toxaphene and Methyl Parathion Residues
on Sweet Corn from Florida: Anal/8109. (Unpublished study re-
ceived Apr 15, 1976 under 891-23; submitted by Hercules, Inc.,
Agricultural Chemicals, Wilmington, Del.; CDL:233962-D)
-------
227
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00085262 Martin, B.W. (1975) Determination of Residues of Methyl Parathion
and Toxaphene. Undated method. (Unpublished study received
Apr 15, 1976 under 891-23; prepared by Everqlades Laboratora-
tones, Inc., submitted by Hercules, Inc., Agricultural Chemi-
cals, Wilmington, Del.; CDL:233962-E)
00086695 Pennwalt Corporation (1968) Residue Chemistry: Introduction: Penn-
cap-M. (Unpublished study received Oct 28, 1981 under
4581-292; CDL:246182-A)
00090488 Edwards, W.R.; Graber, R.R. (1967) Responses of Avians to Methyl
Parathion in a Hayfield. (Unpublished study received on unknown
date under unknown admin, no.; submitted by ?; CDL:130204-A)
00091907 Henderson, C.; Pickering, Q.H. (1957) The Toxicity of Organic
Phosphorus Insecticides to Fish: Mobay 1967. (U.S. Public
Health Service, Bureau of State Services, Robert A. Taft Sani-
tary Engineering Center; unpublished study; CDL:120467-C)
00093895 Ahmed, F.E.; Sagartz, J.W.; Tegeris, A.S.; et al. (1981) One-year
Feeding Study in Dogs: R.D. 1393: Special Report MSL 1967.
(Unpublished study received Jan 25, 1982 under 524-68; submitted
by Monsanto Co., Washington, D.C.; CDL:246638-A; 246640; 246641)
00099011 Nor-Am Agricultural Products, Inc. (1975) Summary: Residue Data
for Tank Mix Applications of Chlordimeform Fundal/Galecron plus
Azodrin, Methyl Parathion/Toxaphene or Methyl Parathion When
Applied to Cotton. (Compilation; unpublished study received
Aug 15, 1975 under 2139-98; CDL:223839-A)
00101095 National Agricultural Chemicals Assoc. (1970) Parathion/Methyl
Parathion Pesticide Petition: Results of Analysis of Root
Crops. (Compilation; unpublished study received Dec 12, 1970
under 1F1091; CDL:090847-C)
00101096 National Agricultural Chemicals Assoc. (1970) Parathion/Methyl
Parathion Pesticide Petition: Results of Analysis of Rye—0.5
ppm. (Compilation; unpublished study received Dec 12, 1970
under 1F1091; CDL.-090847-D)
00101098 National Agricultural Chemicals Assoc. (1970) Parathion/Methyl
Parathion Pesticide Petition: Results of Analysis of Sorqhum—
0.1 ppm (Negligible Residues). (Compilation; unpublished study
received Dec 12, 1970 under 1F1091; CDL:090847-F)
00101100 National Agricultural Chemicals Assoc. (1969) Parathion/Methyl
Parathion Pesticide Petition. (Compilation; unpublished study
received Sep 10, 1969 under OF0878, CDL:090885-A)
-------
223
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00101122 National Agricultural Chemicals Assoc. (1970) Results of Analyses
of Field Treated Cottonseed and Cottonseed Oil. (Compilation;
unpublishd study received May 6, 1969 under OF0878; CDL:
093175-A)
00101124 Univ. of Nevada (1969) Residues of Ethyl and Methyl Parathion
on Alfalfa. (Compilation; unpublished study received Mar 3,
1969, Dec 31, 1970 under 9E0823; CDL:093524-A)
00101213 Monsanto Co. (1964) Residue Studies of Parathion on Sorghum.
(Unpublished study received Sep 11, 1964 under unknown admin.
no.; CDL:122516-A)
00101221 Union Carbide Corp. (1967) Sevithion Residues in Alfalfa Hay—a
Surrmary. (Compilation; unpublished study received Mar 1, 1968
under 1016-EX-28; CDL:126503-D)
00101226 Agchem (1978) Residue Data Introduction: Penncap-E. (Unpub-
lished study received Nov 16, 1978 under 4581-EX-23; CDL:
235971-A)
00101489 Pennwalt Corporation (1978?) Residue Data on Penncap-M Insect-
icide and Permethrin, Including Method Determining Cis and
Trans Isomers of Permethrin. (Compilation; unpublished study
received Apr 5, 1982 under 4581-292; CDL:247267-A)
00102291 Walker, R.; Yeomans, A.; Fahey, J.; et al. (1965) Comparative
Studies of Ultra Low-volume Sprays and Conventional Emulsion
Sprays of Malathion and Methyl Parathion Applied to Cotton for
Insect Control. (U.S. Agricultural Research Service, Entomology
Research Div., Analytical Investigations, Aerosol Investiga-
tions, Biological Investigations and Plant Pest Control Div.;
unpublished study; CDL;005066-B)
00102292 Thornburg, W. (1973) Methyl Parathion Toxaphene Residues in Treated
Tomatoes. (Unpublished study received May 25, 1973 under
891-106; submitted by Hercules, Inc., Agricultural Chemicals,
Wilmington, DE; CDL:005136-A)
C0102312 Docough, H, (19b8) Letter sent to C. Compton dated Apr 19, 1968
Methyl paratnion: Residues in sunflowers. (Unpublished study
received Apr 22, 1968 under 8E0718; prepared by Texas A & M
Univ., Dept. of Entomology, submitted by Rutgers Univ., New
Brunswick, NJ; CDL:093029-A)
00102314 Pennwalt Corp. (1972) Introduction: Pencap M (Methyl Parathion):
Studies on Various Crops. (Unpublished study received on un-
known date under 3F1361; CDL:093631-A)
-------
229
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRJD CITATION
00102329 Pennwalt Corp. (1972) Pencap M—LC50 for Bobwhite Quail. {Unpub-
lished study received Mar 6, 1973 under 3F1361; CDL:093632-I)
00102355 Pennwalt Corp. (1974) Discussion: Penncap-M. (Compilation; un-
published study received Jan 10, 1975 under 5E1585; CDL:
094349-A)
00102356 Pennwalt Corp. (1973) Residues on Crops—Methyl Parathion. (Com-
pilation; unpublished study received Jan 14, 1977 under 4581-
292; CDL:095714-A)
00102362 Bouchard, D. (1970) Cotton: Residue Studies with Various Pes-
ticides. (Unpublished study received May 6, 1971 under 876-
125; submitted by Velsicol Chemical Corp., Chicago, IL; CDL:
101519-A)
00102367 Stranz, J. (1963) Methyl Parathion: Residue Studies on Soybean
and Soybean Stalks (Hay)—Including a Description of the Analyt-
ical Method Used. (Unpublished study received Aug 12, 1963
under 524-128; submitted by Monsanto Co., Washington, DC; CDL:
119346-A)
00102370 FMC Corp. (1965) Residues of Methyl Parathion in Beans. (Ccrt-
pilation; unpublished study received Jul 29, 1966 under 279-
1321; CDL:119655-B)
00102372 Shellenberger, T. (1970) Letter sent to K. Nolan dated Dec 30,
1970: A simulated field toxicity evaluation of Cyqard-630 in-
secticide: GSRI Project No. NC-400. (Unpublished study received
on unknown date under 241-EX-49? prepared by Gulf South Research
Institute, submitted by American Cyanamid Co., Princeton, NJ;
CDL.-123157-B)
00102376 Peterson, R.; Pasarela, N. (1969) Malathion and Methyl Parathion
Residues in Ground Undelinted Cottonseeds: Report No. C-181.
(Unpublished study received Feb 19, 1969 under 241-EX-49; sub-
mitted by American Cyanamid Co., Princeton, NJ; CDL:123158-G)
00102405 McCann, J. (1970) Methyl Parathion 4 Lb.: Bluegill (Lepomis macro-
chirus): Test No. 228. (U.S. Agricultural Research Service,
Pesticides Regulation Div., Animal Biology Laooratory; unpub-
lished study; CDL:129778-A)
00102414 Waldron, A.; Coleman, D.; Estesen, B. (1967) Ethyl and Methyl
Parathion Residues in Alfalfa: Project Report No. 3. (Unpub-
lished study received Jun 24, 1968 under unknown admin, no.;
prepared by Ohio Cooperative Extension Service, Pesticide Chem-
icals Residue Laboratory, submitted by American Cyanamid Co.,
Princeton, NJ; CDL:223051-A)
-------
230
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00102415 Keckemet, 0. (1975) Residue Data: Methyl Parathion. (Unpublished
study received Dec 29, 1975 under 4581-OC-16; submitted by
Pennwalt Corp., Philadelphia, PA; CDL:223517-A)
00102417 Keckemet, 0. (1977) Residue Data: Penncap-M. (Unpublished study
received Feb 3, 1977 under 4581-292; submitted by Pennwalt
Corp., Philadelphia, PA; CDL:228033-A)
00102418 Keckemet, 0. (1977) Residue Data: Penncap-M. (Unpublished study
received Mar 29, 1977 under 4581-EX-24; submitted by Pennwalt
Corp., Philadelphia, PA; CDL:228782-A)
00104198 Velsicol Chemical Corp. (1964) Residues of Various Insecticides
on Alfalfa, Red Clover, Milk and Other Crops. (Compilation;
unpublished study received Jan 27, 1961; Aug 30, 1963; Dec 24,
1963; Jan 20, 1964 under unknown admin, no.; CDL:122412-B)
00105217 Ciba-Geigy Corp. (1978) The Results of Tests on the Amount of
Residues Remaining Including a Description of the Analytical
Methods Used: Curacron. (Compilation; unpublished study
received Mar 3, 1978 under 100-598; CDL:096851-A; 096852;
096853; 096854; 096855)
00113173 Mitchell, M.; Russell; Cleveland, R.; et al. (1971) Cygard 630:
Malathion, Methyl Parathion and Methyl Paraoxon Residues in
Undelinted Cottonseed: Report No. C-261. (Unpublished study re-
ceived Mar 8, 1971 under unknown admin, no.; prepared in cooper-
ation with Syracuse Univ. Research Corp., submitted by American
Cyanamid Co., Princeton, NJ; CDL:120007-A)
C01190C7 Daly, I.; Hogan, G. (1982) A Two Generation Reprodugtion Study of
Methyl Parathion in Rats: Project No. 80-2456; BD-80-139. Final
rept« (Unpublished study received Dec 9, 1982 under 524-68;
prepared by Bio/dynamics, Inc., submitted by Monsanto Co.,
Washington, DC; CDL:248971-A)
00124901 Simmon, V.; Mitchell, A.; Jorgenson, T. (1977) Evaluation of Se-
lected Pesticides as Chemical Mutagens: In vitro and in vivo
studies: EPA-600/3-77-028: Pre RPAR Review Submission 13. (Un-
published study received Sep 14, 1977 under 1471-35; prepared by
Stanfonf Rc-searcl* Institute, Environmental Toxicology Div.,
Health Effects Research Laboratory, and U.S. Environmental
Protection Agency, Office of Research and Development, submitted
by Elaiico Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN, CDL:233222-L)
00127239 Ulland, B,; Gordon, E.j Cardy, R.; et al. (1979) Bioassay of Methyl
parathion for Possible Carcinogenicity. By U.S. National Insti-
tutes of Health, National Cancer Institute, Div. of Cancer Cause
and Prevention, Carcinogenesis Testing Program. Bethesda, MD:
USNIH. (DHEW publication no. (NIH) 719-1713; also in unpublish-
ed submission received Mar 9, 1982 under unknown admin, no.;
submitted by Stauffer Chemical Co., Richmond, CA; CDL:247782-A)
-------
231
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CnATION
00128039 Anon, (W^) Source unknown. (Also in unpublished submission
received on unknown date under 524-EX-14; submitted by Monsanto
Co., Washington, DC; CDL:123776-E)
00128790 Bailey, H. (1983) Chronic Toxicity of Penncap M to Daphnia magna:
SRI Pro3ect LSC-4652. Rev. final rept. (Unpublished study re-
ceived Jun 30, 1983 under 4581-293; prepared by SRI Interna-
tional, submitted by Agchem Div. , Pennwalt Corp., Philadelphia,
PA; CDL:250628-A)
00128791 Bailey, H. (1983) Chronic Toxicity of Penncap M to Rainbow Trout
(Salno gairdnern) : SRI Project LSC-4652. Rev. final rept.
(Unpublished study received Jun 30, 1983 under 4581-293; pre-
pared by SRI International, submitted by Agchem Div., Pennwalt
Corp., Philadelphia, PA; CDL:250628-B)
00128792 Beavers, J.; Jaber, M.; Fink, R. ; et al. (1983) One-generation
Reproduction — Bobwhite Quail: Penncap-M: Project No. 110-
129. Final rept. (Unpublished study received Jun 30, 1983
under 4581-293; prepared by Wildlife International, Ltd. and
Johns Hopkins Univ., Dept. of Biostatistics, submitted by Agchem
Div., Pennwalt Corp., Philadelphia, PA; CDL:250628-C)
00128793 Beavers, J.; Jaber, M.; Fink, R. ; et al. (1983) One-generation
Reproduction — Mallard Duck: Penncap-M: Project No. 110-130.
Rev. final rept. (Unpublished study received Jun 30, 1983 under
4581-293; prepared by Wildlife International/ Ltd. and Johns
Hopkins Univ., Dept. of Biostatistics, submitted by Agchem
Div., Pennwalt Corp., Philadelphia, PA; CDL:250628-D)
00132949 Mortelmans, K.; Riccio, E.; Shepherd, G. (1980) In vitro Detection
of Mitotic Crossing-Over, Mitotic Gene Conversion and Reverse
Mutation with S. Cerevisiae D7 for Seven Pesticides: SRI Project
No. LSU-7558-20; Contract No. 68-02-2947. Final rept. (Unpub-
lished study received Dec 5, 1983 under 239-2471; prepared by
SRI International, submitted by Chevron Chemical Co., Rich-
mond, CA; CDL:251894-C)
00137986 FMC Corp. (1965) Study: DDT, Toxaphene and Methyl Parathion Resi-
due Data on Beans. (Compilation; unpublished study received
Aug 1, 1966 under 279-1321; CDL:119204-A)
00138662 Ross, B.; Loper, G.; Harvey, J. (1980) Chemical Detection of
Penncap-M Capsules in Honey Bees ...: Collected Pollen and
Methyl Parathion Analyses of Honey Bees and Bee Products from
Five Apiaries in the Vicinity of Cotton . . . Fields Treated with
Four Applications of Penncap-M -Yuma, AR. , 1980. (Unpublished
study received Jan 11, 1984 under 4581-292; submitted by Agchem
Div., Pennwalt Corp., Philadelphia, PA; CDL:252448-B)
-------
232
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Methyl Parathion Standard
MRID CITATION
00138663 Waller, G.; Hanny, B.; Harvey, et al. (1983) A Comparison of Honey
Bee losses with Two Formulations of Methyl Parathion Applied to
Sunflowers. (Unpublished study received Jan 11, 1984 under
4581-292; submitted by Agchera Div., Pennwalt Corp., Philadel-
phia, PA; CDL:252448-C)
00138667 Smith, W.; Kritsky, G. (1982) Preliminary Report on the Effects of
Penncap-M on Honeybees. (Unpublished study received Jan 11,
1984 under 4581-292; prepared by Tri-State Agri Research, sub-
mitted by Agchem Div., Pennwalt Corp., Philadelphia, PA; CDL:
252448-G)
00153356 Pennwalt Corp. (1985) Application for Amended Registration of
Penncap-M Microencapsulated Insecticide ULV Application to
Cotton. Unpublished compilation. 32 p.
05000819 Korn, S.; Earnest, R. (1974) Acute toxicity of twenty insecticides
to striped bass, Morone saxatilis. California Fish and Game
60(3):128-131.
05004211 Bowman, M.C.j Beroza, M. (1967) Temperature-programmed gas
chromatography of 20 phosphorus-containing insecticides on 4
different columns and its application to the analysis of milk
and corn silage. Journal of the Association of Official
Analytical Chemists 50(6):1228-1236.
05008363 Hudson, R.H.; Haegele, M.A.; Tucker, R.K. (1979) Acute oral and
percutaneous toxicity of pesticides to mallards: correlations
with mammalian toxicity data. Toxicology and Applied
Pharmacology 47(3):451-460.
-------
OMB AoofOftl No 20O&04S8 (Exfurn 123183)
FIFHA SECTION 3(C){2KB) SUMMARY SHEET
EPA REGISTRATION NO
PRODUCT NAME
APPLICANT'S NAME
DATE GUIDANCE DOCUMENT ISSUED
With rapKl to ttii nqummtm to submit "gtntne" data imposed by tht FIFRA ncbon 3(C)(2)(8) nottct contained in tht rc(o«ictd
Gwdanct Document. I am ropondmg m On foUowmt. manntr
O 1 I will mibmit data HI * Bmtry manntr to atafy th« (otlawmi nqmnnranu. II th« tut proudurts I wnH u» dunm from (or »i nai
tpKifltd m) tfit Rtgatntran Gutddma or tfit Protocott commd m th« Rtpam of Expttl Groups to the Chtmiuls Group. OECO
Chtmiuls Ttstng Prognmmi, I mdoM th« protocols thit I will urn
D 2. I h»v« mttnd Into in qmmm »rtt> om or i
raquirimtntx. Th* wa, tnd toy rvqund protocols, wtt b* mibmrmd to EPA by
rwib undv FIFRA wetion 3(C)(2)(B)(iO to trsfy th« lollovm| dm
NAME OF OTHER REGISTRANT
D 3 I tndoM • eomplmd "CtrtrfcatiM of Ammpt to Emir Into tn AgntrMnt with Othtt Rifotrtnu (or Oivtlopmtnt o< 0*u" with
r«ptct to Oil following d«ta ftquinmintt:
O 4 I raquM thit you tmtnd my regotntlofi by dtlftmg tht following USM (th« option • not tvitoblt to mpliunti for ntw productt)
D 5. I nquM vohinunr etnoUMon tf tht rtootmion of tha product. (Th« option « not wwUWt ID wptcana (or ntw producttj
REGISTRANT'S AUTHORIZED REPRESENTATIVE
EPA Fen* tMO-1 (10*2)
SIGNATURE
DATE
-------
OMB Approval No 20O&0468 (E«vm 1231-83)
(To qtmlify. ctrtify ALL four item)
CERTIFICATION OF ATTEMPT TO ENTER
INTO AN AGREEMENT WITH OTHER REGISTRANTS
FOR DEVELOPMENT OF DATA
1 I am duly authorized to represent the following firm(i) who are subject to the require-
ments of • Notice under FIFRA Section 3(c)(2M8> contained in a Guidance Document
to submit dau concerning the active ingredient
GUIDANCE DOCUMENT DATE
ACTIVE INGREDIENT
•4AMC of FIRM
SPA COMPANY NUMBER
(This firm or group of firtm is referred to below at "my firm" )
2. My firm a willing to develop and submit the data as required by that Notice, if neceuary However, my firm would prefer to enter
into an agreement with one or more other registrants to develop tointly, or to (hare in the con of developing, the following required
items or data
3. My firm he* offered M writing to enter mto welt «n •oreemem. Copies of KM off en art attached That offer we* irrevocabli and included en offer to bt
Bound try tfi srbtfitlicn iSscuon -adw EICB*. S«r""o 3(d(2)(B)(ni) if final agreement on all Urms could not bt reached otherwise. Tho offer was made
to tht fsilcwmj fcm(i) on th« following datt(s) "
FIRM
DATE OF OFFER
However, none of thote firm(i) ecceptud my offer
4 My firm requests that'EPA not suspend the registrat*on(s) of my firm's product(s), if any of the firms named in paragraph (3) above
Ki?r*yTWd to-sutmit the data lined m paragraph (2) above in accordance with the Notice I understand EPA will promptly inform
-B»e~wh«thec..rrjyJirTT) mutt submit data to^avoid suspension of its regi*tr»noti(i) -rvder FIFRA Section 3(c)(2)(B) (This natement
doe* not apply to applicants for new producn t I give c?A per-n.ision f> <*'t*ow this statement upon request.
TYPED NAME
EPA Form 8680-6 (10-82)
SIGNATURE
DATE
-------
PRODUCT SPECIFIC DATA REPORT
EPA Reg. No.
Date
Guidance Document for
Registration
Guideline No.
S158.120
PRODUCT
CHEMISTRY
61-1
61-2
61-3
62-1
62-2
62-3
63-2
63-3
63-4
63-5
63-6
63-7
*
63-8
63-9
63-10
63-11
63-12
Name of Test
Identity of
ingredients
Statement of
composition
Discussion of
formation of
ingredients
Preliminary
analysis
Certification of
limits
Analytical methods
for enforcement
limits
Color
Physical state
Odor
Melting point
Boiling point
Density, bulk-
density, or
specific gravity
Solubility
Vapor pressure
Dissociation
constant
Octanol/water
partition
coefficient
PH
Test not
required
for ray
product
listed
above
(check
below)
-
I am corplyinc
data require™
Citing MRID
Number or
EPA Accession
Number
>
••> , » - ,
3
3 witn
snts by
Submit-
ting
Data
(At-
tached)
m
""*"
—
* ' z
(For EPA Use Only)
Accession Numbers'
Assigned
,
• »
\
t
i
t
** -**~" — »** j
J 0 ' v*. ;
V '«<. f * V "
. . , ?
. . , ' f
*
*— — - «,. — = — .. ^ w
<
— *. ^, j
. j
""„' '-**..'_' *' **v t vV^l
r>i-r» r , in1 'rf( C*i
-------
,_ Registration
Guideline No.
— 63-13
63-14
63-15
63-16
63-17
63-18
63-19
63-20
63-21
, 5,158.135
"TOXICOLOGY
81-1
81-2
•
81-3
- , 81-4-
'i - -i
'•: ' 81-5 i r
81-6
J i
Name of Test
Stability
Oxidizing/reducing
reaction
Flattroability
Explodability
Storage stability
Viscosity
Miscibility
Corrosion
characteristics
Dielectric break-
down voltage
Acute oral
toxicity, rat
Acute dermal
toxicity, rabbit
Acute inhalation,
toxicity, rat
Prinary eye
^irritation p rabbit
-Primary dental
irritation
Etermal sensitiza-
tion
Test not
requireo
for my
product
listed
above
(check
below)
I am .complying with
data >requirements by
Citing MRID
Number or
EPA Accession
Number
Submit-
ting
Data
(At-
tached)
•
(For EPA Use Only)
Accession Numbers
Assigned
•
-------
FOPMULATOR'S EXEMPTION STATEMENT
(40 CFR 152.85)
EPA File Symbol/Reg. No. - Product Name
. v •"
Applicant's Name and Address
As an authorized representative of the applicant for registration of the
product identified above, I hereby certify that:
~0
(1) This product contains the active ingredient(s):
(2) Each active ingredient listed in paragraph (1) is present solely
as the result of the incorporation into the product (during formulation or
packaging) of another product which contains that active ingredient, which
is registered under FIFRA sec. 3, and which is purchased by us from another
producer.
(3) Indicate by circling (A) or (B) below which paragraph applies:
(A) An accurate Confidential Statement of Formula (EPA Form-8570-41 for
the above identified procuct is attached to this statement. That_fprmula
statement indicates, by company none, registration number and-product
name, the source of tne active ingredient(s) listed in paragraph jU).
CR __
(B) The Confidential Statement of Formula dated on file #rith
the EPA is complete, current and accurate and contains the information
required on the current CSF Form No. 8570-4. The registered source(s)
of the active ingredient(s) listed in paragraph (1) is/are listed below;
Active ingredient Source; Product name and Reg. No.
Signature
Date Title
EPA Form I April 1985)
------- |