United States        Office of          EPA 520/1 -8W)15
               Environmental Protection     Radiation Programs       August 1986
               Agency          Washington, D.C. 20460
               Radiation
<&EPA         Laboratory - Determined
               Concentration Factors And
               Elimination Rates Of Some
               Anthropogenic Radionuclides
               In Marine Vertebrates And
               Invertebrates

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                                 EPA 520/1-85-015
Laboratory-Determined Concentration Factors
          and Elimination Rates of
    Some Anthropogenic Radionuclides in
    Marine Vertebrates and Invertebrates
                August 1986
        Office of Radiation Programs
    U.S. Environmental Protection Agency
            Washington, DC 20460

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                             FOREWORD


     In response to the mandate of Public Law 92-532, the
Marine Protection, Research and Sanctuaries Act, as amended, the
Environmental Protection Agency (EPA)  has developed a program to
promulgate regulations and criteria to control  the ocean disposal
of radioactive wastes.  An important technical  consideration in
an/ environmental assessment of this option is  the potential for
biological uptake of radioactivity as  it moves  through marine
food chains which could lead to man.  An understanding of the
range of concentrations and biological elimination rates of key
radionuc1 ides found in marine organisms is fundamental.
     This report reviews and summarizes the experimental
literature on radionuc 1. ide concentration factors and biological
turnover rates of selected radionuclides.   It also provides a
comparison of laboratory-determined concentration factors with
field-derived values.  The isotopes of low-level waste selected
lor inclusion are plutonium, americium, cesium, strontium, and
cobalt.  The data are presented by isotope and according  to
the various groups of marine organisms for which data are
available.  The concentration factor data are summarized  in
tables that include comments concerning conditions of the
experiment.  Figures are included that compare laboratory and
fie Id-derived concentration factor values for each isotope.

     These data are useful for predictive modelling both  to
estimate concentrations of specific nuclides which may occur
in fish or invertebrates from any past or future ocean disposal
activities and to predict the resultant dose to man from
ingestion of these seafoods.

     The Agency invites all readers of this report to send any
comments or suggestions to Mr. David E. Janes, Director,  Analysis
and Support Division, Office of Radiation Programs (ANR-461),
Environmental Protection A.gency, Washington, D.C. 20460.
                             Sheldon Meyers,Acting Director
                          Office of Radiation Programs  (ANR-458)

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                                   CONTENTS

Abstract   	    xii
Introduction   	      1
  Objective  	      1
  Concentration Factors	      1
     Measurement of Concentration  Factors   	      2
     Application of Concentration  Factors   	  ....      4
     Patterns of Concentration Factors  	      5
  Elimination Rates  	      8
     Derivation of Elimination Rates    	      9
     Determination of Elimination  Rate  Constants  	    11
Plutonium	    12
  Physicochemical Form	    12
  Primary Producers  	    13
     Concentration Factors 	    13
        Microalgae   	    13
        Macroalgae   	    16
     Elimination Rates 	    16
        Microalgae   	    16
        Macroalgae   	    17
  Annelida - Polychaeta  	    17
     Concentration Factors 	    17
     Elimination Rates 	    19
  Mollusca	    20
     Concentration Factors 	    20
        Pelecypoda	    20
        Gastropoda	    20
        Cephalopoda	    24
     Elimination Rates 	    24
        Pelecypoda	    24
        Gastropoda	    26
        Cephalopoda	    26
  Arthropoda -  Crustacea	    26
     Concentration Factors .	    26
     Elimination Rates 	    28
                                     m

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  Chordata - Pisces	     28
     Concentration Factors	     28
     Elimination Rates	     29
Americium    ........ 	     30
  Physicochemical  Form	     3°
  Primary Producers  	     30
     Concentration Factors  . 	     30
        Microalgae	     30
        Macroalgae   	     ^3
     Elimination Rates 	     33
        Microalgae   	     33
        Macroalgae   	     33
  Annelida - Polychaeta  	     34
     Concentration Factors  	     34
     Elimination Rates 	     34
  Mollusca	     36
     Concentration Factors  	     36
        Pelecypoda   	  .......  	     36
        Gastropoda	     36
        Cephalopoda	     36
     Elimination Rates 	     39
        Pelecypoda	     39
        Gastropoda	     39
        Cephalopoda	     41
  Arthropoda - Crustacea 	     41
     Concentration Factors  	     41
     Elimination Rates 	     43
  Chordata - Pisces	     43
     Concentration Factors  	     43
     Elimination Rates 	     43
Cesium	     43
  Physicochemical  Form	     43
  Primary Producers  	     45
                                      IV

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     Concentration Factors	   45
     Elimination Rates 	  .   50
  Annelida - Polychaeta	•  •   50
     Concentration Factors   	   50
     Elimination Rates 	  ....   50
  Mollusca   	50
     Concentration Factors   ....  	   50
     Elimination Rates ....  	   57
  Arthropoda - Crustacea   	   57
     Concentration Factors   	  ...   57
     Elimination Rates 	   57
  Chordata - Pisces	61
     Concentration Factors	61
     Elimination Rates 	   61
Strontium    	64
  Physicochemical Form	64
  Primary Producers  	   64
     Concentration Factors       	   64
     Elimination Rates 	   64
  Annelida   	68
  Mollusca   	68
     Concentration Factors 	   68
     Elimination Rates 	   68
  Arthropoda - Crustacea 	   68
     Concentration Factors 	   68
     Elimination Rates 	   68
  Chordata - Pisces	72
     Concentration Factors 	   72
     Elimination Rates 	   72
Cobalt     	72
  Physicochemical Form .  . .  <	72
  Primary Producers	  .   74
     Concentration Factors 	   74
     Elimination Rates 	   74

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  Annelida - Polychaeta  	   77
     Concentration Factors	  .   77
     Elimination Rates 	   77
  Mollusca .....  	  ...   77
     Concentration Factors 	  ....•••   ^7
     Elimination Rates		81
  Arthropoda - Crustacea	   81
     Concentration Factors .....  	  ....•••   81
     Elimination Rates ......  	   84
  Chordata - Pisces	84
     Concentration Factors 	   84
     Elimination Rates 	   84
Application of Concentration Factor and Elimination Rate Data    	   87
  Concentration Factors  	   87
  Elimination Rates  	   92
Acknowledgments    	   92
References   .	94

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                                LIST OF  TABLES

1.    Laboratory-derived concentration factors  (CFs)  for
     plutonium in primary producers  	     14

2.    Laboratory-derived concentration factors  (CFs)  for
     plutonium in Annelida - Polychaeta   	  ...     18

3.    Laboratory-derived concentration factors  for  plutonium
     in Mollusca	     21

4.    Biological half-life (days) of plutonium  in Mollusca   	     25

5.    Laboratory-derived concentration factors  (CFs)  for
     plutonium in Arthropoda - Crustacea 	     27

6.    Laboratory-derived concentration factors  (CFs)  for
     americium in primary producers (microalgae)  	     31

7.    Laboratory-derived concentration factors  (CFs)  for
     americium in Annelida   Polychaeta   	     35

8.    Laboratory-derived concentration factors  (CFs)  for
     americium in Mollusca 	     37

9.    Biological half-life (days) of americium  in Mollusca	     40

10.  Laboratory-derived concentration factors  (CFs)  for
     americium in Arthropoda - Crustacea 	     42

11.  Biological half-life (days) of americium  in whole
     Arthropoda - Crustacea	     44

12.  Laboratory-derived concentration factors  (CFs)  for
     cesium in primary producers	    46
                                     VI 1

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13.   Biological  half-life  (days)  of cesium in primary
     producers (macroalgae)   ....
14.   Laboratory-derived  concentration factors (CFs) for
     cesium in Annelida  -  Polychaeta  ......... . ........

15.   Laboratory-derived  concentration factors for cesium in
     Mollusca. ......  ......  .  ................    53
16.   Biological  half-life  (days)  of cesium  in Mollusca.
                                                                           58
17.  Laboratory-derived concentration  factors  (CFs) for
     cesium in Arthropoda -  Crustacea   	    59

18.  Laboratory-derived concentration  factors  for cesium  in
     Chordata - Pisces	    62

19.  Biological half-life (days)  of cesium in  Chordata  -
     Pisces	    63

20.  Laboratory-derived concentration  factors  (CFs)  for
     strontium in primary producers  	    65

21.  Laboratory-derived concentration  factors  (CFs)  for
     strontium in Mollusca - Pelecypoda	    69

22.  Laboratory-derived concentration  factors  (CFs)  for
     strontium in Arthropoda - Crustacea 	    71

23.  Laboratory-derived concentration  factors  (CFs)  for
     strontium in Chordata - Pisces  	    73

24.  Laboratory-derived concentration  factors  (CFs)  for
     cobalt in primary producers  	    75

25.  Laboratory-derived concentration  factors  (CFs)  for
     cobalt in Mollusca  .....  	    78
                                     vm

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26.  Biological half-life (days)  of cobalt  in  Mollusca  -
     Pelecypoda	82

27.  Laboratory-derived concentration  factors  (CFs) for
     cobalt in Arthropoda -  Crustacea   	    83

28.  Laboratory-derived concentration  factors  (CFs) for
     cobalt in Chordata - Pisces	    85

29.  Biological half-life (days)  of cobalt  in  Chordata  -
     Pisces	    86

30.  Values obtained from statistical  analyses of  CFs,  assuming
     a normal distribution and a  lognormal  distribution   	    91

31.  CF values selected for use in models  to  predict  the  dose to
     man or aquatic organisms from the release of  radionuclides
     into marine environments  	    93

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                               LIST OF FIGURES

1.   Hypothetical  model  of the partitioning of a
     radionuclide among  compartments  in  aquatic ecosystems
     Processes in uptake,  incorporation,  and loss  of stable
     and radioactive nuclides of metals (modified  from George
     and Viarengo, 1985).   Nuclide (N)  in seawater and/or in
     the cytosol  may be associated with ligands (L)  of
     different molecular size and affinity for  the metal.
     Within the cytosol, nuclides bound to ligands may be
     associated with metallothioneins  and lysosomes	
3.   Concentration factors (CFs)  for plutonium in marine biota:
     laboratory-derived CFs from  this report (•); field-derived  CFs
     from Noshkin (1985) (•) or Jackson _et _al_.  (1983)  (o)	     15

4.   Concentration factors (CFs)  for plutonium in muscle
     tissue of marine biota:  laboratory-derived CFs from this
     report (o);  field-derived CFs  from Noshkin (1985)  (•)	     23

5.   Concentration factors (CFs)  for americium in marine
     biota:  laboratory-derived CFs from  this  report (•);
     field-derived CFs from Noshkin (1985) (•)	     32

6.   Concentration factors (CFs)  for americium in muscle
     tissue of marine biota:  laboratory-derived CFs from this
     report (•);  field-derived CFs  from Noshkin (1985)  (•)	     38

7.   Concentration factors (CFs)  for cesium  in marine
     biota:  laboratory-derived CFs from  this  report (•);
     field-derived CFs from Noshkin (1985) (•);
     field-derived data from Jackson e_t^ a_l_.  (1983) (o);
     stable-element-derived CFs from Polikarpov (1966)  (o).   . 	     49

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8.   Concentration factors for cesium in muscle tissue of
     marine biota:  laboratory-derived CFs from this
     report (o); field-derived CFs from Jackson et al.
     (1983) (o) or Noshkin (1985)  (•); stable-element-
     derived CFs from Polikarpov (1966) (o) or Pentreath (1977)  (A).  .  .     56

9.   Concentration factors (CFs) for strontium in marine
     biota:  laboratory-derived CFs from this  report (•);
     field-derived CFs from Jackson _et _aj_. (1983) (o)  or
     Noshkin (1985) (t); stable-element-derived CFs  from
     Polikarpov (1966)  (o) or Pentreath (1977) (A)	    67

10.  Whole-body concentration factors (CFs) for strontium in
     muscle tissue of marine biota:  laboratory-derived CFs
     from this report (•); field-derived CFs from Noshkin
     (1985) (•); stable-element-derived CFs from Polikarpov
     (1966) (o) or Pentreath (1977) (A)	    70

11.  Concentration factors (CFs) for cobalt in marine
     biota:  laboratory-derived CFs from this  report (•);
     field-derived CFs from Jackson _et _a_L (1983) (o)  or
     Noshkin (1985) (•); stable-element-derived CFs  from
     Polikarpov (1966)  (o), or Shimizu _et _a_L  (1970) (A)	    76

12.  Concentration factors for cobalt in muscle tissue of
     marine biota: laboratory-derived CFs from this  report
     (•); field-derived CFs from Jackson _e_t _al_. (1983) (o);
     stable-element-derived CFs from Polikarpov (1966) (o)
     or Pentreath (1977) (A)	    80

13.  Concentration factors for plutonium in muscles  of
     fish.   The arithmetic mean is 77 (sigma = 220), and
     the geometric mean is 8.9 (sigma = 8.7)	    90
                                      XI

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                      LABORATORY-DETERMINED  CONCENTRATION
                     FACTORS  AND  ELIMINATION RATES OF  SOME
                     ANTHROPOGENIC  RADIONUCLIDES  IN MARINE
                         VERTEBRATES  AND  INVERTEBRATES
                                   ABSTRACT

     The literature on radionuclide concentration factors and elimination
rates acquired in laboratory experiments is reviewed and discussed, and then
the laboratory-derived concentration factors are compared to those
concentration factors measured directly in organisms collected from marine
environments.  The radionuclides considered in this review are those of
Plutonium,  americium, cesium, strontium, and cobalt.  The groups of organisms
for which data have been acquired are primary producers, annelids, molluscs,
arthropods, and fishes.
     I discuss the measurement, application, and patterns of concentration
factors, as well  as the  derivation and determination of elimination-rate
constants.   In addition, I  have compiled tables of concentration factors and
elimination rates for those radionuclides and groups of organisms for which
sufficient  data are available.
                                     XI 1

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                                 INTRODUCTION

OBJECTIVE

     The objective of this study is to provide data that can be used to assess
the potential for bioconcentration of radioactivity in marine food chains that
could lead to man.  Specifically, the literature on radionuclide concentration
factors and elimination rates acquired in laboratory experiments is reviewed
and discussed, and then the laboratory-derived concentration factors are
compared to those concentration factors measured directly in organisms
collected from marine environments.  Radionuclides designated by the U.S. EPA
Office of Radiation Programs for inclusion in this review are those of
Plutonium, americium, cesium, strontium, and cobalt.  Tables of concentration
factors and elimination rates for major groups of organisms were compiled for
those radionuclides for which sufficient data were available.

CONCENTRATION FACTORS

     Concentration factors have been used in models to predict the
concentration of radionuclides when releases from ocean waste disposal  or
ocean discharges are continuous and steady-state conditions are present.  The
concentration factor (CF) is usually defined as the ratio of the concentration
of the radionuclide (R) in the organism or tissue i, (R-), to that in the
water, (Ru).  Thus, if the concentration of a radionuclide in the water in
an ecosystem is known, the concentrations in aquatic organisms can be
calculated from their CFs.  Some authors have calculated CFs from the
concentration of the radionuclide in the soluble fraction of the water; others
have used total water concentrations.  Furthermore, some CFs have been
calculated from radionuclide concentrations in food-chain organisms and in
sediments.  The use of CFs based on specific biotic and abiotic components is
appropriate when sufficient data are available that indicate that the component
(or components) is the actual source of the radionuclide to the organism of
concern.
     CFs are affected both by the physical and chemical form of the element in
the environment and by the route of entry of the element into the organism.
Many physicochemical forms of radionuclides may exist, and the distribution

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among forms differs with the radionuclide and the  characteristics  of  the
ecosystem (Fig. 1).  The routes of entry of  radionuclides  into  an  organism  are
dependent in part on the organism's feeding  behavior  and  its  habitat.  Major
routes of entry are from radionuclides in solution or suspension  in water and
in food-chain organisms.  However, many organisms  live in  sediments and may
absorb radionuclides from interstitial waters,  from the sediment  directly,  and
from ingestion of sediments.  Unfortunately,  for many radionuclides we do not
know the relative bioavailability of the different physicochemical forms or
the relative importance of the food, water,  and sediment  pathways  for transfer
of the radionuclides to the organisms.

Measurement of Concentration Factors

     Let us consider some of the parameters  affecting the measurement of
concentration factors.   Variations in concentration of stable and  radioactive
nuclides in organisms can be expected because of differences  in their sizes,
ages, and reproductive  states  and because of  fluctuations  in  temperature  and
the concentration of constituents in the environment.  If, as has been
frequently done,  field  measurements of stable or radioactive  nuclide
concentrations of organisms are made at only one point in time and on only
limited numbers of the  population, the CFs obtained may be erroneous. Thus,
to obtain a meaningful  measurement of CF, we may need a knowledge of  the
environmental history of the organism and the composition (size,  age, and sex)
of the population sampled.
     In addition to variations in concentration in the organisms, changes  in
concentration in the water occur because of  seasonal  fluctuations both  in the
run-off from the land and in the hydrodynamic and  meteorologic conditions.
Furthermore, more than  values  for just the total concentration of the nuclide
in the water may be required.   It may be necessary also to have the values  for
the concentrations of prominent chemical and physical species because an
organism may possibly accumulate only one specific form.   Consequently, for a
CF to be valid, it should be established both that the concentration  measured
in the water is that with which the organism has equilibrated and that it is
for the physicochemical form that existed during the  period of equilibration.

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      Insoluble
      orecipitate
Sorption by
 particles
Figure 1.  Hypothetical  model of the partitioning of a radionuclide among

compartments  in  aquatic  ecosystems.

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Application of Concentration Factors

     Wide ranges in CF have been determined for some organisms  (Jackson  et
al., 1983; Noshkin, 1985).   Consequently,  before these are used  in  models,  the
method of obtaining the values should be examined to determine  if they should
be applied to the situation under consideration.
     To select the best CF  to apply, one must understand something  of the
nature of the physiological processes that have resulted in the  concentration
difference between the organism and its environment.
     The uptake and loss of a radionuclide may follow the uptake and loss of
its stable nuclide or of related stable or radioactive nuclides  that have
similar physicochemical properties.  Therefore, to be able to predict the
behavior of some radionuclides, it may be necessary to understand the
metabolism of stable and radioactive nuclides of other elements.
     The uptake and loss of elements continues throughout the life  of the
organism and may vary considerably with fluctuations in metabolic demands.
When the rate of uptake exceeds the rate of loss, a concentration buildup
between the organism and its environment will ensue.  This concentration
buildup may be maintained by a process such as binding to subcellular
constituents and cellular metabolites or by processes that require  the
expenditure of metabolic energy.  Thus, CFs may be altered by factors that
affect metabolic activity.
     The accumulation of a  specific element may occur because of needs of
growth, reproduction, and skeleton formation, or because the mechanism for
loss is less effective than that for uptake.   The material accumulated may  be
in distinct chemical, organ, or tissue pools.  Thus, its distribution in the
organism may be distinctly  heterogeneous,  and a large fraction  of the material
may be localized in a small mass.
     Mechanisms have frequently evolved in organisms for increasing the rate
of uptake of an element when the environmental concentrations are  low and
decreasing it when metabolic demands have been met.  When an excess of an
element is accumulated, there is a need for its removal.  Excesses  can be lost
by elimination of the element back across  the body surface or gills and
excreting it into the gut or the urine, or can be metabolically  inactivated by
temporarily or permanently  storing it in a different form in a particular
tissue.  Tissues known to be important storage sites for many elements are  the
liver (or hepatopancreas) and the kidney.   Some aquatic organisms appear to be

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able to regulate the concentration of elements by combining the processes of
absorption, excretion, and storage.  The ability of organisms to regulate
element concentrations has been assessed by analyzing tissues from organisms
exposed to different concentrations of the element of interest.  Homeostatic
control of element concentrations has been demonstrated for a number of
elements in fishes, but for only a few elements in invertebrates.
     Accumulation can be affected also by the modifications that may occur at
the place of uptake because of the specificity of the binding sites.
Furthermore, because these sites may not discriminate between elements that
are chemically and physically similar, inhibition of uptake may occur as a
consequence of competition for binding sites.  Absorption of elements from
seawater may occur across the general body surface or through a special area
such as gills or walls of the gut (Fig. 2).  Once in the body fluid, they may
remain free or bind to proteins, or they may be accumulated by individual
tissues.  This appears to involve sorption at sites on or within the cells.
Absorption may be an active or passive process, and accumulation may be
related to the stabilities of complexes formed between elements and organic
1igands.

Patterns of Concentration Factors

     Three idealized CF patterns have been described by Vanderploeg et a_j_.
(1975).  The first pattern is that the CF for a radionuclide (R) in organism
or tissue i, CF(R)., is constant, i.e., is unaffected by the concentration
of elements:

     CF(R).  = constant.                                                     (1

This pattern is shown by radionuclides that are not under homeostatic control
and is exemplified by the behavior of plutonium in marine invertebrates and
fishes.
     The second pattern is seen in organisms in which the concentration of an
element in an organism or tissue is under homeostatic control or regulated at
a constant concentration despite different concentrations of the element in
water.  In this case, the CF of the element (E) is inversely proportional to
its concentration in the water:

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 Environment
Membrane
Cytosol
 ML,
  N
  N
  +
  U
  ML,







* „ ,
» »
•
s 9
* . •
.;•.
• . .
« *
« •
* «


' Metallothion
N
+ Aulusui
L _.._.. 	 . Synthesis

, Secon
L3 lysos
($ §
• ... •••.•.•.-.;... ^ ••...•.;•:•. 11
:•••••••/. •••:•• • •: ••/• L3.'.-.-. /.• .-.:- T
N f
                                                               Primary
                                                              lysosome
                                            NL
                                      Endocytosis
                                               Residual
                                               body
                                                         Exocytosis
Figure 2.  Processes in uptake, incorporation,  and  loss  of  stable  and
radioactive nuclides of metals (modified from George  and Viarengo,  1985).
Nuclide (N) in seawater and/or in the cytosol may be  associated  with  ligands
(L) of different molecular size and affinity for the  metal.   Within the
cytosol, nuclides bound to ligands may be associated  with metallothioneins and
lysosomes.

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     CF(E). = E./E  ,                                                       (2)
           i    v  w '                                                       v

where E^   = concentration of stable element in organism or  tissue  i,  a
             constant (ug/g wet weight), and
      E    = concentration of stable element in water (ug/g).

If it is assumed that the specific activity (i.e.,  the ratio of  radionuclide
concentration to the stable element concentration)  in i  is equal  to  that  of
the water, the CF for the radionuclide, CF(R)., is  also  inversely
proportional to the concentration of the stable element:

     CF(R)i - E1/Ew .                                                       (3)

This pattern is exemplified by radionuclides of some elements  in  fishes,  but
by few elements in invertebrates.  The classical  example  of  this  pattern  is
the behavior of I    in mammals in which the concentration of  iodine is
under strict control .
     The third pattern is that the CF for the radionuclide,  CF(R).,  is
inversely  proportional to the concentration of a nonisotopic carrier element
in water (i.e., chemically similar to but occurring in higher  concentrations
than the stable-element analogue).  The derivation  of this relationship
follows .
     The CF for radionuclide R is related to CF(E*).,  the CF for  the
                 *
carrier element E , by
                  *   CF(R)
     CF(R). = CF(E ). —-fL  ,                                              (4)
                      L r ( t j .

which may be written as

     CF(R). = CF(E*)i
                      (R/E )w
          *           *
where (R/E ). and (R/E )   are ratios of radionuclide  concentration to
carrier-element concentration found in the organism or  tissue  and  in the
water, respectively.  Assume that the nonisotopic  carrier  element  is
homeostatically controlled in the organism, that is:

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                                                                            (6)
                                                                            ^
where E-  = concentration of nonisotopic carrier element in  organism or
            tissue i, a constant (yg/g wet weight),
and   E   = concentration of nonisotopic carrier element in  water  (yg/g).
                                                     *       *
Combining equations (5) and (6)  and  letting q^  = (R/E )i/(R/E )w,  the
desired expression is obtained:
     CF(R). = -V- •                                                        (7)
          1    Ew
This pattern is shown  by very few radionuclides in marine organisms.   The
classical example of this pattern is  the  behavior  of  radionuclides  of cesium
in fresh-water animals;  the nonisotopic carrier element is potassium  in  this
case.

ELIMINATION RATES

     The accumulation  of the stable or radioactive nuclide of an  element by any
pathway can involve a  number of different processes.   If the  rate-determining
process can be described mathematically,  a model can  be developed to  predict
changes in concentration with time and location.   A considerable  effort  has
been made to develop models to predict the distribution of radionuclides
released into the environment.  The types of  models developed to  predict
concentrations of radionuclides in aquatic organisms  include  equilibrium and
dynamic models.
     The type of model  to be used in  a given  situation depends  on the nature
of the release and on  the properties  of the ecosystem,  when  releases of
radionuclides are continuous and steady-state conditions are  present, an
equilibrium model such as a CF model  can  be used.   In this case,  the  important
parameter needed for the model is the CF, and the  concentration in  the animal
is determined by multiplying the concentration in  the water by the  CF.  In the
case of accidental episodic releases, the result is a dynamic situation  in
which organisms accumulate the material for a relatively short  period and then
lose it with a characteristic rate constant.   In this case, the important
parameters needed for  the model are CFs and biological  elimination-rate
constants.

-------
     The elimination rate of stable and radioactive nuclides in organisms
depends on dynamic processes of exchange with elements in the environment.
Compartments of elements are identified from a mathematical  analysis  of the
changes in concentration during accumulation or loss.  The resolution of
compartments is limited by experimental error, and the compartments  that can
be identified are those whose concentrations differ significantly in  their
elimination-rate constants.  These compartments may be physiological,
structural, or chemical entities, and their metabolic significance may not  be
known.
     The biological half-life of a radionuclide in an organism depends upon the
organism and the properties of any element to which it may be related.  Data
available on biological half-life of radionuclides indicate that,  in  most
marine organisms, the transfer of radionuclides to and from the water can be
described by one- or two-compartment models.  In small organisms with a large
surface-to-volume ratio, the biological half-life of monovalent elements such
as sodium or cesium may be minutes, whereas in large organisms and multivalent
elements, it may be months.  The biological half-life is  also a function of
the metabolism of the element by the organism.  The quantities accumulated  by
organisms when the concentrations are increased in the water differ  greatly
for those elements that are and those that are not under  homeostatic  control.

Derivation of Elimination Rates

     The rate of change in concentration of a radionuclide (corrected for
radioactive decay to time zero) in an organism at any time may be described by:

     dR-(t)/dt = k1 Rw(t) - k2 R.(t) ,                                       (8)

where
     R (t)   = the concentration in the water at time t,
     R-(t)   = the concentration in the organism or tissue i, at time t,
     k-,      = the biological  accumulation-rate constant,
     k~      = the biological  loss-rate constant.

At steady-state conditions, Rw(t) = constant and dR.(t)/dt = 0, and

-------
                               R (s)     k
                          F=  -±—  =  ^,                                (9)

where
     R-(s)   = the concentration in the organism or tissue i,  at steady-state
               conditions.

     If it is assumed that the radionuclide concentration  in  the water at any
time t is a constant, then equation 8  upon integration  becomes:
             k,R        -k_t
     R.(t) = _Lw [1 - e  2 1  .                                           (10)
      T        K2

Substituting R^(s) = k-|Rw/k2 into equation 10,  we have:
                         -k9t
     R^t) = R^s) [1 - e  l ]  .                                          (11)

     In those situations where the concentration in the organism is  not at
steady-state conditions and the concentration  in the water is  known  and is
constant, the ratio of the concentration in the animal  to  that in the water
(CF ) can be substituted for concentrations in  the animal  to  give:

     CF*(t) = CF(s) [1 - e  2  ]  ,                                        (12)
where
     CF (t)   = the nonsteady-state concentration factor in the  organism at
                t i me t,
     CF(s)    = the concentration factor in the organism at steady-state
                conditions.

The loss of stable or radioactive (corrected for radioactive decay to time
zero)  nuclides may be described by:
                      -k,t
     Ri(t) - R^o) [e   M   ,                                              (13)

where
     R.j(o)   = the radionuclide concentration in the organism  at  time zero,
               the time of equilibrium or  cessation of  exposure.
                                      10

-------
From k?, the biological half-life (T 1/2) of a nuclide in an  organism may be
determined from the relationship:
     T  1/2 =      -  .                                                      (14)
              K2
Determination of Elimination Rate Constants

     The kinetics of radionuclide metabolism have been assessed  both  in whole
organisms and in specific body parts.  Some of the techniques  used  to  determine
elimination rates are by monitoring:
     o  the rate of uptake of radionucl ides in organisms  exposed
        to radionucl ides under controlled laboratory conditions,
     o  the rate of uptake of radionucl ides in organisms  transferred from  a
        pristine to a radionucl ide-contaminated environment,
     o  the rate of loss of radionucl ides in organisms exposed to radionucl ides
        under controlled laboratory conditions and then transferred to a
        pristine environment, and
     o  the rate of loss of radionucl ides in organisms transferred  from a
        radionucl ide-contaminated environment to a pristine environment.

The extrapolation of the kinds of data derived from these types  of  experiments
to specific field conditions must be done with care.  For example,  it  is
extremely difficult to design laboratory experiments that simulate  real-world
conditions and provide the kinds of information required  to predict the
accumulation and redistribution by marine organisms of radionucl ides released
into ecosystems.  Ideally the radionuclide should be presented to the  test
organisms in a manner similar to that which would occur in its habitat.  In the
environment, the radionuclide may be present in the particulate  and soluble
fraction of the water in different physicochemical forms, has  been  incorporated
into the food chain, and has been deposited in the sediments.  Most laboratory
experiments performed do not have all abiotic compartments represented, and the
physicochemical  form of the radionuclide to which the organisms  are exposed is
not defined.  Also, the test organisms should be fed, and the  population
densities in the experimental container should be representative of those found
in the natural  habitat.  For many organisms, insufficient data are  available
on their ecology to permit realistic experimental  design. Furthermore, most
laboratory experiments are not conducted long enough to permit steady-state
                                      11

-------
conditions of uptake and loss to be achieved in all compartments; this results
in underestimation of CF values.  In spite of these limitations, data have been
acquired on elimination rates and accumulation factors that can be used to
evaluate the dynamics of radionuclide transfer in marine food chains.

                                  PLUTONIUM

PHYSICOCHEMICAL FORM

     The chemistry of plutonium is complex and is partly governed by the total
concentration in solution.   Multiple oxidation states  can coexist in solution
and the oxidation-reduction behavior is complicated (see review of Matters _e_t
al., 1980).  There are four principal sources of data  on the behavior of
plutonium: world-wide fallout; nuclear test sites (Marshall Islands and
Nevada); Thule, Greenland;  and nuclear power plant outfalls.
     The behavior of plutonium in seawater has been studied in widely
different ecosystems, and the concentrations measured  differ by as much as
three orders of magnitude.   Because the pH of the ocean is well buffered,
plutonium apparently cannot exist except as Pu(III) or Pu(IV) in solution in
the water column (Matters ert _aj_., 1980).  Plutonium has a high affinity for
particulate material.  This is described by a distribution coefficient (K,):
         K  -       fs       V
          d      (1 - fs)    W  '
where
     fs     = fraction of nuclide on the particulate fraction
     1  - fs = fraction of nuclide in the soluble fraction
     V       = weight of water (g)
     W       = dry weight of particles (g).

The K^  as defined is dimensionless,  and greater sorption of the nuclide to
the particulate fraction results in  higher Kds.
     The mean K^ recommended for use in models of both the pelagic and
coastal  regions of the ocean is 100,000; the range of  values recommended for
sensitivity analysis is from 10,000  to 1,000,000 (International  Atomic Energy
Agency  (IAEA),  1985).  The  oxidation state of plutonium on particles is
                                                                     1 ~\
considered to be Pu(IV).  Somewhere  in the concentration range of 10    to
                                      12

-------
10   _M, plutonium ceases to exhibit the properties of simple ions, and the
possible formation of polymeric species must be considered (Matters et al.,
1980).  Consequently, when moderately concentrated solutions are used in
laboratory experiments, the results should not be used to predict the behavior
of plutonium in the environment.

PRIMARY PRODUCERS

Concentration Factors

     Microalgae.  Studies have shown that plutonium can be strongly
concentrated by primary producers (Jackson et_ _al_. , 1983).  However, few
experimental studies of plutonium uptake by marine phytoplankton have been
conducted despite their importance in geochemical cycling and food chain
processes (Table 1 and Fig. 3).  Fi sher _ejt _aj_. (1980) used environmentally
realistic atom concentrations to test the plutonium uptake by Thaiassiosira
pseudonana, Thaiassiosira sp., Platymonas sp., and glass particles.  Yen
(1981) described the sorption of plutonium by two species of marine
phytopl ankton.  More recently, Fisher _et_ _a_l_. (1983a) determined the ability  of
six clones of marine phytoplankton to accumulate plutonium.
     CFs obtained by Yen (1981) and Fisher et_ a_L (1983a) for phytopl ankton
tested in the laboratory demonstrated about an order of magnitude difference
with species (Table 1).  Some values obtained in the field were lower than
those obtained under laboratory conditions (Fig. 3).  It is not known whether
the low values were due to differences in species or to the absence of
steady-state conditions.  The former is probably the reason because steady-
state conditions are reached relatively rapidly in phytopl ankton (Fisher _e_t
al., 1983a).  Also, it would be expected that CF values determined in the
laboratory would be similar to those determined in the field if the organisms
were exposed to the same physicochemical forms of plutonium.
     Dissolved organic matter (DOM) was found to affect the accumulation of
007                OQ7
   Pu (III-IV)  and    Pu (V-VI) by the marine diatom Thaiassiosira pseudonana
(Fisher et al ., 1983b).  Ethylenediaminetetraacetate at 0.3 unreduced
plutonium uptake,  but marine fulvic and humic acids, naturally occurring DOM,
and diatom exudates did not reduce uptake.
                                      13

-------
Table 1.  Laboratory-derived  concentration factors (CFs) for plutonium in
primary producers.
Organism
Thalassiosira pseudonana
T. pseudonana
Dunaliella tertiolecta
Oscillatoria woronichinii
Ernil iania huxleyi
E. huxleyi
Tetraselmis chuii
Monochrysis lutheri0
M. lutheri0
M. lutheric
M. lutheri
M. lutheri
Phaeodactylum tricornutunf
P. tricornutunf
P. tricornutum0
Ascophyllum nodosum
(brown algae)
A. nodosum
A. nodosum
A. nodosum
A. nodosum

Exposure,
d CFs
1
4
4
4
4
4
4
1
1
1
1
1
1
1
1
15
15
15
15
15
Microalgae
85,000-2,800,000
380,000
150,000
50,000
50,000
330,000
60,000
8100 + 5600
24,300 + 3700
32,800 + 10,700
34,200 + 15,900
44,900 + 12,500
38,100 + 19,800
46,500 + 10,700
72,300 + 26,600
Hacroalgae
797
415
298
578
738
Comments
Varied with
biotic and
abiotic factors
3H clone
Dun clone
OSE N4 clone
MCH No.l clone
BT-6 clone
Tet C2 clone
At 24°C
At 0°C
At 24°C
At 24°C
At 24°C
At 24°C
At 0°C
At 24°C
a Fisher et al. (1980).
b Fisher _et _al_. (1983a).
0 Yen (1981).
d Zlobin and Mokanu (1970).
                                     14

-------
        Primary Producers      Annelida
                                                          Moltusca
                                                                                              Arthropods
                                                                                                               Chordata
1,000.000
 100,000
% 10,000
c
g
fD
^^
g
o
c
5  1000
    100
     10
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Wh
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-
  .Figure  3.   Concentration factors (CFs)  for plutonium in  marine biota:   laboratory-derived CFs from this
   report  (•); field-derived  CFs  from Noshkin (1985)  (•) or Jackson  et  al_. (1983)  (o).

-------
     The accumulation of plutonium appears to be a passive process;  dead cells
accumulated about the same amount of plutonium as living cells (Fisher et_ _a1_.»
1980).  Also, quantities accumulated were higher at low salinities and high
temperatures.  Fisher et_ _al_.  (1983a) investigated the effect of valence state
on accumulation; the CFs of Pu(III-IV) were similar to those of Pu(V-VI).
However, Pu(V-VI) may be reduced to Pu(III-IV) once it is associated with the
cells.  The data available support the hypothesis that plutonium in  marine
environments associates with  suspended particles that could act as vertical
vectors for this element.

     Macroalgae.  Limited data are available on laboratory-derived CFs for
plutonium in benthic algae.  Zlobin and Mokanu (1970) determined the uptake of
plutonium by the brown algae  Ascophyllum nodosum (Table 1).  CF values were the
same order of magnitude as those derived for other algae in the field (Fig. 3).
Guary and Fraizier (1977) proposed that the CF for plutonium is related to the
nature of the algal surface.   They reported a CF of 1175 for Corallina
officinalis which has a calcified and strongly ramified structure, a CF of 523
for Fucus serratus which has  a ramified, noncalcified blade, and a CF of 85 for
Laminaria digitata which has  a large, smooth, noncalcified blade.  Wong et al.
(1972) showed plutonium was accumulated on the very outermost (mucilage) layer
of the kelp Pelagophycus porra.   Spies _et_ _al_. (1981) showed that high
concentrations of plutonium are associated with the coenocytic filaments in
the calcareous algae Halimeda macrophysa.   Evidence currently available on
macroalgae indicates that the likely mechanism for accumulation is by
adsorption and that plutonium may be attached to large macromolecules or
micelles, which have slow diffusivities but great affinity for a variety of
surfaces (Beasley and Cross,  1980).

Elimination Rates

     Microalgae.  For the phytoplankton species examined by Fisher et al.
(1983a), steady-state conditions of uptake and loss of plutonium were reached
within a few days.  Cells accumulated plutonium in proportion to the isotope
concentration in the water, and  the amount of isotope associated with cells was
a direct function of their number (hence surface area).   The data indicate that
isotope accumulation by cells ceased, not  because of saturation of their
surfaces, but because they reached steady-state conditions of uptake and loss

                                      16

-------
 from the  surfaces.   Uptake was  strongly affected by the nature of particle
 surfaces,  and  cells  from  rapidly  growing cultures took up more plutonium than
 did  those  that were  in  late  log phase of growth or were senescent (Fisher et_
_al_.,  1980).  Such differences prevailed even in experiments during which little
 or no  cell division  took  place.   The authors state that most of the differences
 in cellular  plutonium levels  in their experiments can probably be attributed
 to differences in surface physiology related to the growth stages of the
 cultures used  for inocula.   Cells accumulated more plutonium from UV-treated
 seawater than  from untreated or enriched seawater.

     Macroalgae.  Accumulation of plutonium in the brown algae Macrocystis
 pyrifera appeared to be relatively rapid; steady-state conditions of uptake and
 loss were  reached within  a few days (Hodge et. _al_., 1974).  Spies _et ^1_. (1981)
 measured the rate of loss of plutonium from Halimeda incrassata that had been
 transferred  from a highly contaminated crater in the Enewetak Atoll to the
 lagoon that  had a relatively  low  level of plutonium.  The loss of plutonium
 was  found  to be biphasic.  Most of the plutonium was in a fast-exchanging
 compartment  that had a half-life  of 1.4 d; the slow-exchanging compartment had
 a half-life  of about 30 d.

ANNELIDA - POLYCHAETA

 Concentration  Factors

     Accumulation of plutonium by polychaete worms is of interest because they
 live in the  sediments and belong to a zoological group that occurs in deep
water.  These  organisms are expected and have been found in oceanic radioactive
waste disposal  sites.  Also, Noshkin et_ aj_. (1971) found that Nereis sp.
contained the  highest plutonium concentrations of all invertebrates that they
analyzed.  Fowler e_tal.  (1975) showed that Nereis diversicolor readily
             237
accumulated    Pu (VI to IV) from seawater reaching CFs of about 200 (Table 2).
The concentration of plutonium in the bioassay container was held relatively
constant by  changing the water daily and periodically adding some tracer to the
                              237
water.  A marked reduction of    Pu (VI) uptake was noted in worms accumulating
the isotope  from water that had been used for the first worm experiment.  The
                     237
authors suggest that    Pu might have become associated with excreted
metabolites,  e.g.,  mucus,  and was thus rendered less available for
bioaccumulation.
                                      17

-------
Table 2.  Laboratory-derived concentration factors  (CFs) for plutonium  in
Annelida - Polychaeta.
Organism
Hermione hystrix3
H. hystrix3
H. hystrix3
Nereis diversicolor
H. hystrix0
Arenicol a marina
A. marina
Nereis diversicolor
N. diversicolor

Exposure,
d
22
22
20
15
27
21
14
25
25
CFs
370 + 10
275 + 11
0.05 + 0.01
200
130
7
0.002
190
0.001
Comments
Pu(III+IV), water
Pu(V+VI), water
Pu(III+IV) and (V+VI),
sediments
Pu(IV), water
Pu(IV), water
Pu(VI), water
Pu(VI), sediment
Pu, water
Pu, sediment
  Aston and Fowler (1984).
  Fowler et a_L  (1975).
  Grille et
(1981).
  Miramand et _al_.  (1982).
  Murray and Renfro (1976).
                                      18

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                                            239
     A comparison was made of the uptake of    Pu from sediment and seawater
by Nereis diversicolor (Murray and Renfro, 1976).  Plutonium was added to  the
water and the sediment in the IV oxidation state; concentrations used  in the
                           c       c
experiments were between 10  and 10  times higher than those normally  found
                                           OOQ
under field conditions.  Concentrations of    Pu in the worm increased
throughout the 25-d exposure period, but steady-state conditions were  not
reached.  The CF from the sediments was calculated to be 0.001,  that from  the
seawater to be 190.  Under the conditions of the experiment, it  appears that
N. diversicolor obtained most of its plutonium from the seawater.   The authors
compared the sediment CFs to those reported by Noshkin (1972)  for  a marine worm
from Cape Cod; the value for day 15 was about two orders of  magnitude  less than
those Noshkin (1972) measured in the environment.
                                        pOO_OOQ
     The accumulation of sediment-bound    ~   Pu (VI) and of  plutonium in
seawater by the polychaete worm Arenicola marina was determined  by Miramand
et_ _al_. (1982).  Bioavailabil ity from the sediment was low; after 14 days of
accumulation, the CF was only 0.002.  Worms exposed to labeled seawater for
20 d had a CF of about 7.
     The range of plutonium CFs in Annelida determined in the  laboratory was
lower than that determined in the field (Fig. 3).  This is not unexpected
because most of the exposure times were less than the biological  half-life of
plutonium observed in N.  diversicolor (see below) and that might be expected
in other polychaete worms.

Elimination Rates
     The loss of plutonium was followed in N.  diversicolor  that  accumulated
237
   Pu (VI) for 8 d and then were transferred to nonradioactive water  (Fowler
et_ _a_l_., 1975).  The half-life computed for between  days  4 and 35  of the  loss
period was 79 d.  Elimination of plutonium was followed  also  in  Hermione
                             237
hystrix that had accumulated    Pu from contaminated seawater  (Aston  and
Fowler, 1984).  The loss from the worms indicated the presence of two (at
least) pools that had substantially different  biological  half-lives.   The
long-lived pool  had a half-life of 54 d and the short one of  1.3  d.
                                      19

-------
MOLLUSCA

Concentration Factors

     Pelecypoda.  Bivalve molluscs have been used as indicator organisms of
both stable and radioactive nuclides because of their particular efficiency in
accumulating material from the water column.  Because of this characteristic
and its world-wide distribution, the mussel Mytilus edulis has been used as a
sentinel organism (Goldberg et_ _al_., 1978).  However, proper interpretation of
trends in radionuclide concentrations require knowledge of the rates of
elimination of the isotopes as well as their CFs.
     Plutonium CFs determined in the laboratory are available for four
different bivalve molluscs (Table 3 and Fig. 4).  CFs varied with species and
body part.  The highest concentrations of plutonium were found in byssus
threads (Fowler _e_t _al_., 1975).  High concentrations of other radionuclides have
also been found in this material, but the mechanism of binding is not known.
Higher CFs were found in the shell than in the body; the shell also contained
the largest fraction of the activity.  The high concentrations in the shell  may
primarily be the result of uptake by attached periphyton rather than of actual
accumulation into calcified tissues.
     Examination of the changes of plutonium concentration in the body with
time indicated that none of these test organisms had reached steady-state
conditions of uptake and loss with the plutonium in the media.  This lack of
equilibrium is the probable explanation for the range of the laboratory-
derived CFs being lower than that of CFs derived in the field (Fig. 3).

     Gastropoda.  CFs for plutonium that were determined under laboratory
conditions are available for only the gastropod Aporrhais pespelicani. Grille
et_ al_. (1981) determined the accumulation, tissue distribution, and loss of
plutonium in animals that were exposed to the isotope in the water for 20 d.
Accumulation did not reach steady-state conditions in all tissues, and the CF
values differed with the tissue and individual animals (Table 3).  At the end
of the uptake period, more than 80% of the activity was in the shell; the
remaining activity was distributed about equally between the muscle and the
viscera.
                                      20

-------
Table 3.  Laboratory-derived concentration factors  for  plutonium  in Mollusca
Organism
                 Body   Exposure,
                 part      d      CFs
                             Comments
Venerupis decussata0
V. decussatac
V. decussatac
                     Pelecypoda
                Whole     22     74+5
                Whole
                Whole
          22
          20
       61 + 1
          0.006
Mytilus galloprovincial is
(mussel )
M. galloprovincialis
Tapes decussatus (clam)c
T. decussatus0
T. decussatus0
T. decussatus0
Scrobicularia plana
(clam)
S. plana
S. plana
S. plana
S. plana
S. plana
Byssus
Body
Whole
Shell
Muscle
Viscera
Whole
Shell
Body
Whole
Shell
Body
15-25
25
17
17
17
17
14
14
14
42
42
42
1900-4100
27-70
140
250
0-10
10-30
100
0.01
0.005
190
360
40
          Pu  (III+IV), water,
          nonequilibrium
          Pu  (V+VI), water,
          nonequilibrium
          Pu(III+IV) and  (V+VI),
          sediment
          Varied with  size and
          time
          Varied with  animal
          Pu(IV), water
          Pu(IV), water
          Pu(IV), water
          Pu(IV), water
          Pu(VI), sediment
                                                       Pu(VI), sediment
                                                 0.005  Pu(VI), sediment
                                                       Pu(VI), water
                                                       Pu(VI), water
                                                       Pu(VI), water
Aporrhais pespelicani
  (snail)
                    • c
A. pespelicani
             ,c
A. pespelicani
A. pespelicani
             ,c
,c
A. pespelicani
             .c
                    Gastropoda
                Whole     21
Shell
Body
Shell
Viscera
21
21
21
21
 110

140-230
 20-130
 10-20
 20-210
Pu(IV), water

Pu(IV), water
Pu(IV), water
Pu(IV), water
Pu(IV), water
                                     21

-------
Table 3.  (Continued)
Organism
Octopus vulgaris6
Body Exposure,
part d CFs
Cephalopoda
Whole 15 65
Comments
Pu(IV), water
  (octopus)
0_._ vulgaris
CK_ vulgaris
0_._ vulgaris
0^ vulgaris
f
             Whole             15      65
             Muscle            15      15
             Hepatopancreas    15      50
             Branchial heart   15    9300
             and appendages
Pu(IV), water
Pu(IV), water
Pu(IV), water
Pu(IV), water
  Aston and Fowler (1984).
  Fowler _et _a]_. (1975).
  Grille et a]_. (1981).
  Miramand _et _al_. (1982).
  Guary ej; _aj_. (1981).
  Guary and Fowler (1982).
                                      22

-------
10,000
1,000


2 TOO
u
re
0
•4-J
CT3
t»
•4-*
c

-------
     Cep^ajopod_a_,   Data on accumulation of plutonium are available for Octopus
vu1gari_s (Guary et_ a/L > 1981;  Guary and Fowler,  1982).   It is noteworthy that
this octopus effectively accumulated and distributed plutonium among the
internal tissues (Table 3).   Of special interest was that after the two-week
exposure period, 41% of the  plutonium was in  the branchial hearts and
appendages9  which  had a CF of  9300,  The branchial  hearts have been implicated
also in the  uptake of cesium,  cobalt, arnericium, and certain heavy metals.
The unique ability of the br an-mial hearts and appendages to concentrate many
elements may be related to their role in circulatory and excretory processes.
The elements appear to  be localized in intracellular granules that include
pigtnented material.  Similar  granules have been  found in other molluscs and may
be related to lysosomes (George and Viarengos  1985).

Elimination  Rates

     P_e_1_ecy_po_da.  The elimination of plutonium in mussels has been followed
both under field and laboratory conditions.   Mussels that accumulated Pu(IV)
directly from seawater  showed  a two-component  loss  when  placed in unlabeled
seawater (Table 4).  Under the laboratory conditions used by Fowler et_ al .
(1975)5 the  biological  half-life for the short-lived compartment containing 35%
of the total plutonium  was 7 d;  that for the  long-lived  compartment containing
65% of the total plutonium was 776 d.  Mussels that had  accumulated Pu(IV) from
both food and water showed more rapid elimination,  owing to both a shorter
labeling time and  presumably  a more rapid clearance of  labeled material
eliminated as feces. However,, field data of  Goldberg et al „  (1978) on
239 240
   '   Pu indicated a very rapid elimination,  measured  in weeks or months.
     The half-life of plutonium in the clam Venerupis decussata was followed
                                237
in animals that had accumulated    Pu from either contaminated seawater or
sediment (Aston and Fowler,  1984).  Loss of activity in  those clams that had
accumulated  activity from seawater took place  as an approximately single
exponential  function; the-half-life was 50 d.   Loss of  activity from those that
had accumulated activity from  sediments took  place  as a single exponential
function also; the half-life was 24 d.  No good  explanation was given for the
differences  in loss rates.  Because loss was  followed only for 46 d in the
seawater-contaminated clams  and for 25 d in those contaminated from sediment,
the presence of longer  components could have  been missed.
                                      24

-------
Table 4.  Biological half-life (days) of plutonium in  Mollusca.
Organism
                             Body
                             part   Pool  A    Pool  B   Pool  C   Comments
Venerupis decussata
  (c1 am)
V. decussata
                         c
Mytilus galloprovincialis
  (mussel)
M^_ galloprovincial isc

Tapes decussatus
  (clam)
NL_ galloprovincialis6
  (mussel)
M_._ galloprovincialis6
M. galloprovincialis6
     Pelecypoda
Whole   50(100)

Whole   24(100)

Whole  776(65)     7(35)

Whole   39(100)

Whole   62(65)     7(35)
Pu (III+IV) and
(V+VI), water
Pu (III+IV) and
(V+VI), sediment
Pu (VI), water

Pu (VI), water,
labeled food
Pu(IV), water
                             Whole  193(30)    10(40)   2(30)    Pu(IV), water

                             Whole  192(30)    13(40)   1(30)    Pu(VI), water
                             Shell  215(30)     4(40)    --      Water
Octopus vulgar is
  (octopus)
                                 Cephalopoda
                             Whole  560(46)     2(30)
                                 Pu(III+IV), water
  Number in parentheses is the percent of total  activity  in  the  pool.
  Aston and Fowler (1984).
  Fowler _et _a_K (1975).
  Grille _et a_U (1981).
  Guary and Fowler (1981).
  Guary and Fowler (1982).
                                      25

-------
                  -
     Gastropoda.,   ihe gastropod  Aporrhai s  pespel i carn_ lost  L   Pu  at  rates
comparable to those  of the darn  T_ape_£ decussata (half-life  =  53  to 80 d)
(Grille et_ a]_«9  1981).

                              237
     Cephalopoda.,  The loss of   Pu  from  whole jjctopus^ vulgar is  was slow  and
appeared to take  place from two  compartments  (Table  4).   After a  70-d loss
period, the majority (>90%) of the  plutonium  was  in  the branchial  hearts  and
appendages (Guary and Fowler,  1982).

ARTHROPODA - CRUSTACEA

Con centr at iorj^F actors

     The accumulation of  plutonium  by Crustacea has  been monitored in only a
few animals (Table 5). The earliest  research was  performed using  the lobster
Homaris vulgaris.  Ward (1966) followed  the direct uptake by  lobsters of
plutonium from seawater and established  that  near  equilbrium  was  reached  in
the exoskeleton  and  gills after  50  d  of  exposure.  However, at 220 d the
muscles gut, and  hepatopancreas  were  still not at  steady-state conditions.
Approximately 90% of the  total plutonium taken up  by the lobster  was found in
the exoskeleton,  and, as  would be expected, the major portion that accumulated
was lost during  molting.
     The uptake  of Pu(IV) and  Pu(VI)  from  food and water was  followed in  the
shrimp Lysmata j>eti_caudata (Fowler  et_ _a_L, 1975).  No change  in  uptake rate
with different valence states  was detected.   However,, the valence  state of
plutonium in the  media was not documented  during  the course of the experiment.
For this shrimp,  direct uptake from the  seawater  was slow,  and body  burdens
were reduced when  molting occurred.   Shrimp fed daily rations of  labeled
Artemia sp^ for  15 d did  not accumulate  higher levels of plutonium than those
fed a single ration  of labeled Artemia sp.  When  feeding of nonlabeled food
was resumed, the burden in the soft tissues was reduced rapidly.
     Plutonium was incorporated  into  the hepatopancreas of  the edible crab
Cancer pagunis that  had been fed contaminated food.   Absorption of plutonium
in the hepatopancreas was as high as  5%; < 0.3% was  present in the hemolymph
(Fowler and Guary, 1977).  Investigations  were conducted to determine the
subcellular distribution  of plutonium in the  hepatopancreas of crabs that  were
contaminated jn_ \nvo_ with b9Fe (Guary and  Negrel,  1980). When the cytosolic
                                      26

-------
Table 5.  Laboratory-derived concentration factors (CFs) for plutonium in
Arthropoda - Crustacea.
Organism
Body     Exposure,
part        d        CFs   Comments
Lysmata seticaudata (shrimp)
Corophium volutator (amphipod)
C. volutator
Homaris vulgar is (lobster)1
Whole     25
Whole     14
Whole     12

Muscle   250
5-19   Pu(VI), water
0.1    Pu(VI), sediment
1000   Pu(VI), water,
       nonequi1ibrium
3      Water
  Fowler _et aj_. (1975).
  Miramand _et aj_. (1982).
  Ward (1966).
                                      27

-------
                                                           o o 7
fraction of the hepatopancreas was incubated in vitro with    Pu,  approximately
20% of the plutonium was associated with compounds of molecular weight ranging
from 10,000 to 40,000.  The investigators proposed that these  proteins could
belong to the metallothionein family that has been shown to bind other heavy
metals such as cadmium, copper, zinc,  and mercury.  About 70%  of the plutonium
eluted in the very low molecular weight fraction,  which was below the
operational range of the Sephadex 6-200, and the authors suggest that this
plutonium was present as free metal.  The distribution of plutonium was
different than that of   Fe9 which was bound primarily with a  soluble
protein of high molecular weight (M50,000).

Elimination Rates

     Limited data are available on the half-life of plutonium  in Crustacea.
Fowler ert _al_. (1975) found the loss of plutonium from shrimp was most rapid
when it was ingested with food.  The initial rapid loss was due primarily to
clearance of the gut; the slower loss  was due to other excretory processes.
When shrimp were exposed to plutonium  in water, most was present in the
exoskeleton.  Consequently, molting resulted in a  rapid change in  the body
burden and a change in the kinetics of elimination.  Molts may play an
important role in the biogeochemical cycling of plutonium because  the CF  in
crustacean exoskeleton is high and plutonium in the molt is lost slowly.   In
those areas where the bulk of marine animal  biomass is composed of small
Crustacea that molt frequently, cast molts may be  an important mechanism  for
transporting plutonium to sediments as well  as to  detrital  feeders (Fowler e_t
_aJL, 1976).

CHORDATA - PISCES

Concentration Factors

     Laboratory-determined CFs for marine fishes are few in number; more  field-
determined values are available (Figs. 3 and 4).  Data available were obtained
by Pentreath (1978a, 1978b) who studied the uptake of 237Pu (VI) by plaice
(Pleuronectes platessa) and by the thornback ray (Raja clavate).  The
assimilation of    Pu by plaice was followed in fish exposed to the isotope  in
                   237
water,  in fish fed    Pu-contaminated  Nereis sp.,  and in fish  injected with

                                      28

-------
 the  radionuclide.   Uptake from the water was very slow; after a 63-d uptake,
 the  CF  was <1.   Of  the plutonium accumulated, most of it was in the digestive
 tract.   Plutonium was detectable in the livers of six of the seven fish used,
 and  only traces  were measurable in blood cells, plasma, and bone of two fishes,
     The thornback  ray, a cartilaginous fish, appeared to assimilate more
 237
   Pu than the plaice.  When rays were fed Nereis sp. that had been injected
 with the radionuclide, and crab hepatopancreas that had been incubated  with
 237
   Pu,  the isotope  was found consistently in the liver.  In one fish, 0.2% of
 the  administered dose was found in the liver.  Also, in rays that had been
              237
 injected with    Pu, there were high concentrations of the radionuclide in the
 spleen  as well as the liver.
     It  is clear that the thornback ray differs from the plaice in the  ability
          237
 to absorb    Pu  from labeled food.  In comparable experiments, the plaice
 livers  did not contain more than 0.005% of the total plutonium given in a
 single  labeled meal, whereas the thornback ray livers contained up to 0.23% of
 the  plutonium administered.  Also, the thornback ray had a higher estimated
 percentage of the body burden in the skeleton than did plaice.

 Elimination Rates
     Data on the biological half-life of plutonium are available  only  for
                                             237
plaice  (Pentreath, 1978a).  The retention of    Pu by plaice fed  injected
Nereis  sp. and then fed unlabeled Nereis sp. was determined.  The half-life
                                                                        237
measured in 10 fish ranged from 9 to 49 d.  When fish were injected with    Pu
(IV) intramuscularly, the half-life was considerably longer; values ranged
between 642 and 877 d.  Similar results were obtained from fish that had been
injected directly into the body cavity; half-life values ranged from 282 to
1100 d.  There was marked redistribution of the isotope within fish after they
were injected with the isotope.  The redistribution was independent of the site
of injection and resulted in the highest accumulations occurring  in the liver,
kidney, and spleen.  Growing fish incorporated a relatively larger fraction of
    ?37
the    Pu body burden into skeletal material than nongrowing fish, and this
was attained at the expense of the isotopic content of the liver.  Very little
237
   Pu was incorporated into muscle.
                                      29

-------
                                  AMERICIUM

PHYSICOCHEMICAL FORM

     The major source of americium to the environment is from nuclear weapon
testing..  It was assumed because the americiurn3  like plutonium,,  was present in
high -fired oxide paitk'GS that it. would not  dissolve in natural waters.
However, experimental  dria f.-osri a wide variety of environments does not bear
out this assumption, end americium has been reported in the soluble fraction
of marine waters from a number of environments (see review of Matters et_ _a_K ,
1980).
     Americium is known to form complexes that affect its physicochemical form
and increase the total concentration of the metal in the water.   In seawater,
the most likely oxidation state is the III.,
     Information on the biogeochemistry of americium in marine environments
indicates that most of the americium that was deposited in the ocean from
atmospheric fallout and nuclear wastes was transferred to the sediments.  The
K, recommended for use in models of  both the  pelagic and coastal region of
the ocean is 250005,000; the range recommended for sensitivity analysis is from
100,000 to 20,000,000 (IAEA, 1985).   However, it appears that americium is not
irreversibly retained on sediment particles,,  but can be released into
interstitial waters and hence into the water  column upon changes in the
concentration of americium in the overlaying  waters (Noshkin and Wong, 1980).

PRIMARY PRODUCERS

Coficertrat,ion Fa. c tors
                  Americium concentration factors in marine plankton at steady-
state conditions were in the same range as those for plutonium (cf.  Tables 1
and 6; Figs. 3 and 5).   Appreciable differences were determined with species,
but cells accumulated americium in proportion to the radionuclide concentration
in the water (Fisher _et. _a]L , 1983a)<,  The uptake by dead cells was compared to
that by live cells for  two species.  Uptake was identical ,  indicating that the
uptake process was passive.  Uptake was not affected greatly by the  presence
or absence of light, changes in salinity^ or the presence  of other metals.
                                      30

-------
Table 6.  Laboratory-derived concentration factors (CFs)  for americium  in
primary producers (microalgae).a
Organism
Exposure,
  d
  CF
Comments
Thalassiosira pseudonana
Dunaliella tertiolecta
Oscillatoria woronichinii
Emiliania huxleyi
E_._ huxleyi
Tetraselmis chuii
Heterocapsa pygmaea
Monaco port particles

Offshore particles
3 to 7
3 to 7
3 to 7
3 to 7
3 to 7
3 to 7
3 to 7
3 to 7

3 to 7
410,000
130,000
  7,000
 70,000
150,000
 50,000
280,000
110,000

640,000
3H clone
Dun clone
OSE N4 clone
MCH No. 1 clone
BT-6 clone
Tet C2 clone
Gymno clone
Natural
assemblages
Natural
assemblages
  Fisher et al. (1983a).
                                      31

-------
      Primary Producers  Annelida
                                       Mollusca
Arthropoda
                                                                          Chordata
  100,000 L-
   1 o.ooo U
    1,000l-
 -
 o
o
100 H
      10 U
      1.0 h
      0.1
Microalgae
Field

-


—

-
Lab
*
®
«
!
•
•
»














Polychaeta
Whole
Lab
»



1
*
•









Pelecypoda
Whole
Lab






Body
Lab


•
•
«

Shell
Lab

•

«®











Gastropoda
Body
Lab


«



Shell
Lab

0













Cephalopoda
Whole
Field



0


Lab




»










Crustacea
Whole
Lab
•
f
Q
®

•
•
•










Pisces
Skeleton
Field
-


®
i
-
  Figure 5.   Concentration  factors  (CFs) for  americium  in marine  biota:

  laboratory-derived CFs from this  report (•);  field-derived CFs  from Noshkin

  (1985) (•).
                                           32

-------
 However,  the uptake of americium was  directly  proportional to the cell
 concentration in  the water  and  was  related  to  the  size and surface area of the
 plankton.   The effect of  naturally  occurring dissolved organic matter (DOM) on
 the uptake of americium by  Thalassiosira  pseudonana was determined (Fisher _et
 al_.,  1983b).  They concluded  that the DOM did  not  appreciably affect the
                                                                O A ~\
 bioavailability of the americium.   The cellular distribution of    Am was
 studied  in two algal  species: the diatom  Thalassiosira pseudonana and the naked
 green  alga Dunaliella tertiolecta (Fisher et_ al_.,  1983c).  After a 72-h
 exposure  of the algae to  the  isotope,  94% of the cellular 241Am was found in
 the 745  x  g and 2000  x g  pellets.   These  data  indicate that most of the 241Am
 is  associated with cell walls or membranes  and does not generally bind to
 soluble  cellular  proteins.

      Macroalgae.   No  data on  laboratory-derived CFs of americium in macroalgae
 were  available.

 Elimination Rates

      Microalgae.   Different species of phytoplankton accumulated americium
 rapidly, but the time to  approach steady-state conditions differed with the
 species; the range was from 2 to 4  d  (Fisher ert _al_., 1983a).  The loss of
 americium  was followed in two species,  Thaiassiosira pseudonana and Dunaliel!a
 tertiolecta (Fisher _ejt _a_L, 1983a).   Loss curves were described by a two-
 compartment model  with a  rapid  initial  loss (being greater in size in short-
 term  exposed cells)  and a subsequent,  more  gradual loss.  These investigators
 proposed that this  probably reflected  the presence of two americium
 compartments in the cells, with  a greater fraction of cellular americium in
 the more rapid  compartment.  Biological half-lives in the rapid- and
 slow-elimination compartments were <1  to  1  d,  and  10 to 12 d, respectively.

                              241
     Macroalgae.   The loss of     Am was monitored  from Halimeda incrassata
 that had been transferred from  a  highly contaminated crater in the Enewetak
                                                         241
 Atoll to the lagoon,  which had  a relatively low level of    Am (Spies et
 al., 1981).   The loss  rate constant for the fast-exchanging compartment was
0.49 (half-life of  1.4 d)  and for the  slow-exchanging compartment was 0.067
 (half-life  of 10.3  d).  These exchange rates were similar to those obtained
for plutonium and europium.

                                       33

-------
ANNELIDA - POLYCHAETA

Concentration Factors

     Concentration factors for americium in the same species of nereidae worms
were generally higher for americium than plutonium (cf. Tables 2 and 7).  Only
a few values are available for the uptake of americium from seawater (Fig. 4),
and these differ widely.  It is not known whether the differences are due to
species, analytical methods, or the absence of steady-state conditions.  One
potential source of variability is the presence of food or sediment in the gut
of the worms.  These materials generally have higher affinities for americium
than worm soft tissues; varying amounts of these substances in the gut could
affect the CF value obtained.  Another source of variability is the
physicochemical form of the americium in the water.  Murray et_ al_. (1978) found
that the CF obtained in freshly prepared water was different from that obtained
in aged water, and that the CF was also affected by the pH of the water and
the partitioning of the americium between the soluble and particulate phases
of the water.
     The CF values were considerably lower for uptake from sediment than from
water (Beasley and Fowler, 1976;  Vangenechten et _al_., 1983).  The values
determined by Beasley and Fowler  (1976) from uptake from the sediment showed
an increase with increased exposure time; these were based on the dry weight
of the animal and sediment.

Elimination Rates

     The accumulation of americium by worms from seawater occurred rapidly;
steady-state conditions of uptake and loss were reached in a few days (Beasley
and Fowler, 1976; Murray et _a]_.,  1978; Grille _et _a]_., 1981; Miramand et _a_L,
1982).   Grille et al_. (1981) followed the loss of 241Am from the polychaete
Herrnione hystrix.  Analysis of the loss curves indicated the presence of at
least two distinct compartments within the worm.  A long-lived compartment was
identified that contained about 60% of the activity,  and radioactivity from
this  compartment was  eliminated with a biological  half-life of 66 d (calculated
for the period between  the 15th and 50th day).  From the smaller short-lived
compartment,  radioactivity was eliminated with a half-life of 6 to 7 d.
                                      34

-------
Table 7.  Laboratory-derived concentration factors (CFs) for americium in
Annelida - Polychaeta.
Organism
Nereis diversicolora
N. di versicolora
N. diversicolora
N. diversicolor3
Hermione hystrixc
H. hystrixc
H. hystrixc
Arenicola marina
A. marina
Nereis diversicolor
N. diversicolor6
Hermione hystrix

Body
part
Wholeb
Wholeb
Wholeb
Whole
Whole
Body wal
Setae
Whole
Whole
Whole
Whole
Whole
Exposure,
d CFs
5
15
40
225
22
1 22
22
14
21
20
20
40-50
0.0012
0.002
0.0024
0.004
1000
1900-2200
8000-13,000
2000-3000
18
2-4
16-21
0.05-0.12
Comments
Am in
Am in
Am in
Am in
Am in
Am in
Am in
Am in
Am in
Am in
Am in
Am in
sediment
sediment
sediment
sediment
seawater
seawater
seawater
sediment
seawater
aged seawater
fresh seawater
sediment
a Beasley and Fowler (1976).
  Calculated from the dry weight of worm and sediment.
c Grille et al. (1981).
d
  Miramand et _al_. (1982).
e Murray et _al_.  (1978).
f Vangenechten _et _al_.  (1983).
                                      35

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MOLLUSCA

Concentration Factors

     Pelecypoda.  Americium CFs are available for three species of bivalve
molluscs (Table 8).  The CFs differed with species and body part (Grillo et
_a_L, 1981;  Miramand et _al_., 1982;  Vangenechten _et _aj_., 1983).   Most of the
activity was associated with the shell,  and steady-state conditions of uptake
and loss were not reached.   In Tapes decussatus.,  the uptakes of americium and
Plutonium were followed simultaneously in  the same animals.  At the end of the
3-wk exposure, plutonium was accumulated to a lesser extent than americium.
However, because steady-state conditions were not reached,  it  can not be
concluded that this same relationship would continue with time.  In
Scrobicularia plana, accumulation  from seawater and sediments  was determined
independently.  The CFs calculated from the sediments  were  lower than those
from the water.  However, if the concentration of americium in the interstitial
water of the sediments instead of  the concentration of the  sediments is used
in the calculation, the CFs are more similar to those  obtained with the
americium in the seawater.   No field-derived CFs  are available for Pelecypoda
(Figs. 5 and 6).

     Gastropoda.  Data on the accumulation of americium by  gastropod molluscs
are available for only Aporrhais pespel icani (Grillo et_ a!., 1981).  The CF
values obtained and the kinetics of bioaccumulation were similar to those for
the clam Tapes decussatus.   In this organism also, the uptakes of americium
and plutonium were followed simultaneously in the same animals.  Similar to
J_. decussatus, the CFs for  americium after the 3-wk exposure were higher than
those for plutonium.

     Cephalopoda.  CFs were determined for the cephalopod Octopus vulgaris
(Table 8).   The animals were exposed to  americium and  plutonium concurrently
for 15 d.  Examination of the accumulation curves for  both  elements showed that
equilibrium had not been reached.   Accumulation of plutonium appeared to be
more rapid  than that of americium;  after 2 weeks  the whole-body CFs were 35 for
americium and 65 for plutonium.  CFs for both elements were  high in the gills,
but the highest CFs were found in  the branchial hearts and  appendages (7100 for
americium compared to 9300  for plutonium).   In the branchial hearts, the

                                      36

-------
Table 8.  Laboratory-derived concentration factors (CFs) for americium in
Mollusca.

Organism

Tapes decussatusa
( c 1 am )
T. decussatus3
T. decussatusa
Scrobicularia plana
( c 1 am )
S. plana
S. p!anab
S. p1anab
S. plana
S. plana
S. plana
Venerupis decussatac
( c 1 am )

Aporrhais pespelicania
(snail )
A. pespelicania

Octopus vulgaris
(octopus)
0. vulgaris

a Grille et _al_. (1981).

Body
part

Shell

Body
Muscle
Whole

Shell
Body
Shell
Body
Shell
Body
Whole


Shell

Body

Whole

Muscle



Exposure,
d
Pelecypoda
20

20
20
14

14
14
14
14
32
32
40-50 0

Gastropoda
20

20
Cephalopoda
15

15




CFs

500

330
30
0.009

0.01
0.01
228
137
220
60
.004-0.02


580

330

35

33






Am

Am
Am
Am

Am
Am
Am
Am
Am
Am
Am


Am

Am

Am

Am




Comments

in seawater

in seawater
in seawater
in sediment

in sediment
in sediment
in interstitial water
in interstitial water
in seawater
in seawater
in sediment


in seawater

in seawater

in seawater

in seawater



c Vangenechten et _al_. (1983).
d Guary and Fowler (1982).
                                      37

-------
                           Mollusca
Arthropoda
Chordata


1000
100
k.
8
0
(13
| 10
ro
Vm
C
CD
U
C
o
0
1
0.1
0.01
Pelecypoda
Lab

—
.


—








—
—


















Cephalopoda
Lab









9
























Crustacea
Lab


»































Picsas
Field
—
—



—
t>






@*
—
—
Figure 6.  Concentration factors  (CFs) for  americium in  muscle tissue of
marine biota:  laboratory-derived CFs from  this  report  (•);  field-derived CFs
from Noshkin (1985) («).
                                      38

-------
radionuclides are associated with granular pigment deposits  or  adenochromes
that occur in the cells and may be important in detoxication processes
(Miramand and Guary, 1981).
     When contaminated food is ingested, americium is efficiently assimilated
(mean = 33%) into the tissues of the octopus (Guary and  Fowler,  1982).  These
investigators state that this assimilation coefficient is  of the same order of
magnitude as that measured for plutonium in crabs  (Fowler  and Guary, 1977) but
is 30 times higher than coefficients for plutonium in fish (Pentreath,
1978a, b) and 300 to 3000 times those of transuranic nuclides in mammals.
Guary and Fowler (1982) proposed that the high degree of assimilation of
americium may be linked to the high food-conversion efficiency  reported for
CL vulgaris.

Elimination Rates

     Pelecypoda.  Data on the biokinetics of americium in  bivalve molluscs are
available for the clam Tapes decussatus and for the mussel Mytilus
galloprovincialis (Table 9).  In the clam, at least two  distinct compartments
that were eliminated at substantially different rates were found.
Radioactivity in the short-lived compartment had a half-life of 6 d  and in the
long-lived compartment, 80 d.
     Biological half-lives of americium were determined  in mussels that had
                0 A~\
been exposed to    Am in the laboratory and then transferred to small cages
anchored in the littoral zone off Monaco (Guary and Fowler,  1981).  Loss of
   Am was described as the sum of three exponential functions.   Two  short-
lived compartments were identified.  These represented a total  of 80% of the
incorporated radionuclide and had half-lives of 2  and 3  wk.   The remaining
            241
fraction of    Am was associated with a long-lived compartment  that  was lost
very slowly (half-life of 1.3 y).  Loss rates of americium differed  with body
part, with the most rapid occurring in gill, viscera, and shell.  Some
                               241
indication of translocation of    Am fi
muscle during depuration was obtained.
                               241
indication of translocation of    Am from other  tissues  to  the mantle  and
     Gastropoda.  In the gastropod Aporrhais pespe1icani_,  americium was  lost
at rates comparable to those of the clam J_._ decussatus (Grille et_ a!.,  1981).
Two compartments were identified, one that contained about 65% of the
                                      39

-------
Table 9.  Biological half-life (days) of americium in Mollusca.1
Organism
                                 Pool  A     Pool  B    Pool  C     Comments
Tapes decussatus (clam)
                                  Pelecypoda
                                 80(55-65)  6(35-45)
Am in seawater
Mytilus galloprovincialis
  (mussel)
                                 480(25)     22(40)     11(40)     Am in seawater
Aporrhais pespelicani
  (snail)
                    .b
                                  Gastropoda
                                 80(65)     6(30)
Am in seawater
Octopus vulgaris
  (octopus)
                                 Cephalopoda
                                 560(46)    2(30)
Am in seawater
  Number in parentheses  is  the  percent  of  total  activity  in  the  pool.
  Grille £t _aj_.  (1981).
  Guary and Fowler  (1981).
  Guary and Fowler  (1982).
                                     40

-------
 incorporated radionuclide and  in  which  elimination was very slow, and another
 that represented about 30% of  the radioactivity  and  in which elimination was
 rapid.

      Cephalopoda.   Data on the loss  of  americium are available for CL vulgaris
 (Guary  and  Fowler,  1982).  Whole  body  loss occurred with two compartments.  The
 short-lived compartment,  which contained  about 30% of the initial activity,
 turned  over very rapidly; half-life  of  about 2 d.  Radioactivity in the long-
 lived compartment had  a half-life of 560  d.  These investigators proposed that
 the  short-lived  compartment could represent principally the skin, which
 eliminated  the radionuclide very  rapidly, whereas the long-lived compartment
 could represent  the branchial  hearts, which lost the radioactivity very slowly.

 ARTHROPODA  - CRUSTACEA

 Concentration Factors

      One  of the  early  studies  of  the uptake of americium in crustaceans was
 performed on brine  shrimp and  euphausiids by Fowler and Heyrand (1974).  A
 higher  CF was obtained for the brine shrimp Artemia sp. than for the euphausiid
 Meganyctiphanes  norvegica (Table  10).   A  short-term experiment was performed
                                        241
 with  Artemia sp.  to determine  uptake of    Am from a labeled population of
 phytoplankton.   Uptake from the food appeared to be less efficient than that
 from  seawater; a  CF of 400 was  reached with the tracer in the food and of 1700
 with  the  tracer  in  the seawater.   Filtration of the seawater showed that most
        241
 of the    Am was  associated with  the phytoplankton.  When the CF was calculated
                           241
 from  the  concentration of   Am in the  seawater  in which the phytoplankton were
 suspended,  a CF  similar to that obtained from the water alone was calculated.
 The authors  concluded  that little americium was accumulated from the food.
      The  accumulation  of  americium was followed also in the brackish-water
 amphipod  Gammarus duebeni  and  the harpacticoid copepod Tisbe holothuriae
 (Murray et^ _aj_.,  1978).  The CF was affected significantly by the
                             243
 physicochemical form of the   Am in the water; aging of the water before
 the addition of the organisms  reduced the CF values obtained.   The uptake by
              243
 G. duebeni of    Am from  contaminated food was followed for 10 d.  Unlike
	                                     243
 the uptake from the water  alone,  the uptake of    Am steadily increased;
 steady-state conditions were not  reached in the course of the experiment.

                                      41

-------
Table 10.  Laboratory-derived concentration factors (CFs) for americium  in
Arthropoda - Crustacea.
Organism
Body     Exposure,
part        d        CFs     Comments
Arternia _sp.
  (brine shrimp)
Meganyctiphanes norvegicac
(euphausiid)
Crab or Lobster"1
Crab or Lobster
Gammarus duebeni
  (amphipod)
Corophium volutator
  (amphipod)
C_._ volutator
C. volutator
Gammarus duebeni6
  (amphipod)
G_._ duebeni
Tisbe ho1othuriaee
  (copepod)
Cirolana borealis
  (isopod)
Whole
Whole
48
64
1700     Am in seawater
 125     Am in seawater
Muscle      8          5     Am in seawater
Muscle      8         25     Am in seawater
Whole    12 to 16   25-56    Am in aged seawater

Whole      14          0.12  Am in sediment

Whole      14       1200     Am in seawater
Whole      14       2700     Am in interstitial
                             waters of sediment
Whole      10        300     Am in seawater

Whole      10         40     Am in aged seawater
Whole       7       1070     Am in seawater

Whole    40-50   0.006-0.032 Am in sediment
a Fowler and Heyrand (1974).
  Guary (1980), cited from Jackson et jfL (1983).
C Hoppenheit et _al_.  (1980).
d Miramand ot_ a_K (1982).
6 Murray et_ a]_. (1978).
  Vangenechten et al. (1983).
                                      42

-------
Elimination Rates

     Biokinetics of americium in Crustacea have been determined  for  a  number
of species.  The early work of Fowler and Heyrand (1974)  did  not provide  a
value of biological half-life, but the authors report that accumulation was
rapid.  In the brine shrimp Artemia sp.,  steady-state conditions were  reached
in 48 h; in the euphausiid Meganyctiphanes norvegica, steady-state conditions
                           	                241
were reached in 64 h.  When a single euphausiid that had  accumulated    Am
was placed in unlabeled seawater, it lost 40% of its burden during the first
8 d.  When the animal molted, it lost almost all of its activity.
     Guary (1980) determined the elimination of americium in  a number  of
decapod crustaceans (Table 11).   Elimination was rapid, and only one
compartment was identified.

CHORDATA - PISCES

Concentration Factors

     No data on CFs are available for fishes that were exposed to americium in
the laboratory.  However, CFs are reported for tissues from fish exposed  to
americium under field conditions (see reviews of Jackson  _et _aj_., 1983  and
Noshkin, 1985).  In muscle tissue, the CF values reported ranged from  0.05 to 5
(Fig. 6), in liver from 74 to 104, and in the skeleton from 25 to 178  (Fig. 5).

Elimination Rates

     No data on biological half-life of americium in fishes were found.

                                    CESIUM

PHYSICOCHEMICAL FORM

     Cesium, like other alkali metals, exists primarily as free  ions and  does
not form inorganic complexes.  In solution, it behaves like potassium, which
is present in greater abundance than cesium and serves as a nonisotopic carrier
element.  The concentration of cesium in  surface and deep seawater  is  0.3 vig/kg
                                      43

-------
Table 11.  Biological  half-life (days)  of  americium in  whole  Arthropoda
Crustacea.a*b
Organism
Prawn or shrimp
Prawn or shrimp
Prawn or shrimp
Prawn or shrimp
Prawn or shrimp
Prawn or shrimp
Prawn or shrimp
Pool
45(100)
5(100)
8(100)
2(100)
3(100)
5(100)
20(100)
Comments
Am in seawater
Am in seawater
Am in food
Am in food
Am in food
Am in food
Am in food
a Number in parentheses  is  the  percent of total  activity  in the pool
b Guary (1980),  quoted from Jackson et al.  (1983).
                                     44

-------
 and 0.3 mg/kg, respectively, and that of potassium is 399 mg/kg for both areas
 (Quinby-Hunt  and Turekian, 1983).  Because cesium sorbs to particulate
 material,  especially clays,  it is present in higher concentration in
 sedimentary material.  The mean and range of distribution coefficients,  K,s,
 recommended for use in models of pelagic waters are 2,000 and from 500 to
 20,000; recommended mean and range Kds for models of coastal waters are  3,000
 and from 100  to 20,000, respectively (IAEA, 1985).  Because the Kd for cesium
 is relatively  low, stable and radioactive nuclides of cesium in marine
 ecosystems are primarily in  the water column as soluble, ionic forms,  and they
 behave conservatively.

 PRIMARY PRODUCERS

 Concentration Factors

     Concentration factors for cesium in primary producers are generally low
 (Table 12).   Because of the chemical similarities and relative abundances of
 cesium and potassium concentrations in the water, potassium serves as  a
 nonisotopic carrier for cesium.  Comparison of the CFs determined for  field and
 laboratory populations for radioactive cesium and stable cesium shows  that the
 ranges overlap except for the field-determined values for microalgae (Fig. 7).
     The uptake of cesium by killed cells of Ulva lactuca gave CF values of 1-2
 (Gutknecht, 1965).  Also, seaweeds that had been exposed to    Cs for  up to
 35 d released more than 90% of their activity when killed and kept for several
 hours in the same radioactive medium.  This investigator concluded that  neither
 physical adsorption, adsorption exchange, nor nonexchangeable binding  could
                        137
 account for much of the    Cs taken up by the seaweeds examined.
     The effect of external cesium concentration on cesium uptake was  examined
 in Gracilaria foliifera, Fucus vesiculosus, Ulva lactuca, and Porphyra
 umbilicus (Gutknecht,  1965).   A plot of log cesium uptake vs log  external
 cesium concentration was linear,  indicating that uptake was exactly
 proportional  to external concentration.  This investigator stated that these
                                                     137
 results are consistent with the data indicating that    Cs in seaweeds is
 mainly ionic and not extensively adsorbed.
     Cesium uptake was stimulated by light  in all  species examined (Gutknecht,
 1965).   This  was first observed by Scott (1954), who suggested a  connection
between the mechanisms of cesium  accumulation and photosynthesis.

                                      45

-------
Table 12=   Laboratory-derived  concentration factors  (CFs) for cesium  in primary
producers.
Organism
Nitzschia closteriumc
„ , a
Amphora sp.
Nitzschia sp.
Chlamydomorias sp,
Chlorella sp,a
Pyramimimonas sp.a
Nannochloris atomusa
Ulva sp. (green alga)
Enteromorphia sp, (green alga)
Fucus serrata (brown alga)
F. serrata
r j- b
F. serrata
Chrondrus crispus (red alga)
C. crispus
Corallina sp. (red alga)
Chrondus crispus (red alga)c
Acetabularia mediterranea
(green alga)
A. mediterranea
A., mediterranea
A. mediterranea
A. peniculus
A. peniculus
Batophora oerstedii
B, oerstedii
Boerges_en;i_a forbesii
Exposure,
d
Microalgae
13
13
13
13
13
13
13
Macroalgae
74
31
31
153
44
74 4
107
74 859
100-200
13
13
14
3-7
17
3
13
19
13
CFs
1.2
1.5
1.7
1.3
2.4
2.6
3.1
3 4
O ,H
4
6
16
4
,10,19
10-15
,13,13,14
10-20
13
1
1-2
<1

-------
Table 12.  (Continued).
Organism
B. forbesiid
B. forbesiid
Fucus serratus (brown alga)
Porphyra sp. (red alga)
Ulva lactuca (green alga)
Porphyridium curentum (red alga)a
Ulva lactuca (green alga)6
Codium decorticatum (green alga)e
Fucus vesiculosus (brown alga)6
Dictyota dichotoma (brown alga)6
Porphyra utnbilicalis (red alga)6
Chondrus crispus (red alga)6
o
Gracilaria foliifera (red alga)
Agardhiella tenera (red alga)6
Q
Hypnea musciformis (red alga)
Monostroma sp. (green alga)
Scytosiphon lomentarium (brown alga)
Gracilaria confervoides (red alga)
Ulva ridiga (green algae)"
Cystoseira barbata (brown alga)^
Sargassum natans (brown alga)
S. fluitans
Green alga"1
Green alga1
Green alga1
Brown alga1
Brown alga1
Brown alga1
Red alga1
Red alga1
Red alga1
Red alga1
Exposure,
d
19
3
8
6
8
13
35
35
35
35
35
35
35
35
35
1
1
1
64
64
32
32
26
26
26
26
26
26
26
26
26
26
CFs
%1
<1
2
4-7
24-28
1.3
7
4
30
10
5
30
2.5
6
11
1.2
2
1.6
4-10
30
3.7
10.2
3.4 + 0.2
1.8 + 0.0
1.6 + 0.0
10 +_ 0.6
11.5 +_ 0.6
2.9 + 0.2
3.8 + 0.0
6.3 + 0.4
4.9 ^ 0.2
3.9 +_ 0.2
Comments
Effluent b
Effluent d
Effluent d
Effluent d
Effluent d
                                     47

-------
Table 12.   (Continued)
Organism                                  Exposure,    CFs          Comments
                                             d

Fucus vesiculosus  (brown alga)1-1             45           50          Sulfate form
	—          ^
Cyrtymenia sp. (red alga)'1                  11            5             ---

a Boroughs et _al_.  (1957).
b Ancellin and Vilquin  (1968).
c Avarques et _al_.  (1968).
d Bonotto et aj_. (1981).
e Gutknecht (1965).
  Hiyama and Shimizu (1964).
9 Polikarpov (1961),
h Polikarpov (1964).
1 Ryndina (1972), cited from Jackson _et _al_.  (1983).
J' Scott (1954).
k Ueda et al.  (1978).
                                      48

-------
                 Primary Producers
                                   Annelida
                                                                    MoHusca
                                                                                                       Arthropoda
                                                                                                                        Chordata
-pa
UD
         10,000
         1,000
          100
           10
             _o
           0.1
          0.01
               Microalgae
                  1
                                   Polychaeta
Pelocypoda
Who
0
o

1
TT
0
8
o
00
O



a











A
••
Sho








O


o












?
B<



A

*

I



1
dy






.




t













Gasliopodii
Wh








0
o


l«











•
Bo






.
.




Jy












Sh











O
•ii

























Cephalopoda
Ah







O



o
0
0
1.

























Cru.c.e..
Wh






£b
99°
o

o
o
'•












Exoih


O









eleton











*













PllCOT
Wh




O
%
&
$
H^1


#'
ro
O
,i.











s
4
a.







A
•















-
       Figure  7.   Concentration factors (CFs)  for cesium  in  marine biota:   laboratory-derived  CFs from  this
       report  (•); field-derived CFs  from Noshkin (1985)  (•),  field-derived data  from Jackson  ejt aj_.  (1983) (o);
       stable-element-derived CFs  from Polikarpov (1966)  (o).

-------
Elimination Rates

     Information on the metabolism of cesium in primary producers is available
for only a few species of macroalgae (Gutknecht, 1965; Spies et_ jil_., 1981).
Half-lives ranged from 2 to 21 d (Table 13).

ANNELIDA - POLYCHAETA

Concentration Factors

     Limited data are available on cesium for polychaete worms (Table 14).
Values reported for different species were < 10 for worms exposed only 11 d
as well as those exposed for 58 d.  Rapid achievement of steady-state
conditions is expected because of the small size of most marine annelids.
     Experiments were conducted to determine the relative importance of
                                             137
sediment and seawater on the accumulation of    Cs by Nereis japonica (Ueda
_e_t _al_. 5 1977).  Worms were placed in direct contact with contaminated sediments
and also suspended in the seawater above the sediments.  Although those in
                                                                     137
direct contact with the sediments acquired greater concentrations of    Cs,
the amount the worms acquired from the seawater was about 30 times greater than
that from the sediments.

Elimination Rates

                 137
     The loss of    Cs from both fed and unfed Nereis japonica was followed
(Ueda et_ _al_., 1977).  The loss was relatively rapid and similar for both groups
of worms.  The half-life was calculated to be 6 d for unfed worms and 8 d for
fed worms.
     Elimination of cesium was followed in Neanthes diversicolor.  In the whole
worm, the half-life was 8 d (Ueda et_ aj_., 1976).

MOLLUSCA

Concentration Factors

     More data are available on CFs of cesium in Pelecypoda than  for other
classes  of  Mollusca (Table 15).  Data on the soft tissues were generally

                                      50

-------
Table 13.  Biological half-life (days)  of  cesium  in  primary producers
(macroalgae).

Organism                                         Poola              Comments

Ulva lactuca (green alga)                          5
Codium decorticatum (green alga)                   15
Fucus vesiculosus (brown alga)                     8
Porphyra umbilicalis (red  alga)                   3
Chondrus crispus (red alga)                       2
Gracilaria foliifera (red  alga)                   12
Agardhiella tenera (red alga)                      21
Halimeda incrassata (calcareous alga)c             3
a
  The percent of the total  activity in  the  pool  is  100
b Gutknecht (1965).
c Spies (1981).
                                      51

-------
Table 14.  Laboratory-derived concentration factors (CFs)  for cesium in
Annelida - Polychaeta.
Organism
Arenicola marinaa
A. marina
Nereis diversicola
N. diversicola
N. japonica
N. japonica0
N. japonica0
N. japonica
M • - d
N. japonica

Exposure, d
21
21
58
33
11
11
11
11
14
CFs
2-3
4-5
7.5
6.3
6 + 1
5
0.16
0.2
0.18
Comments
Nonequilibriun
From sediment
From water
From food
and water
From sediment
From sediment
From sediment
  Amiard-Triquet  (1975)
  Bryan  (1963).
  Ueda et  a/L  (1977).
  Ueda et  al.  (1978).
                                     52

-------
Table 15.  Laboratory-derived concentration factors for cesium in  Mollusca,
Organism
Scrobicularia planaa
(clam)
S. plana3
S. plana3
S. plana3
Macoma balthica3
M. balthica3
Chlamys operculata (clam)
C. operculata
Tapes sp. (clam)
-r b
Tapes sp.
Cardium edulis (clam)
C. edulisb
Mytilus edulis (mussel)
M. edulisb
Gyphaea ang.
Gyphaea ang.
Mytilus galloprovincial is
(mussel )
M. edulisd
Chlamys sp. (clam)
Tapes sp. (clam)
d
Tapes sp.
M. edulis
M. edulisf
M. edulis
M. edulisf
M. edulis
M. edulisf
M. edulis
M. edulisf
M. edulis
Body
part Exposure,
Pelecypoda
Body 21
Body 21
Shell 21
Shell 21
Body 21
Shell 21
Flesh 21
Shell 44
Flesh 74
Shell 31
Flesh 100-200
Shell 100-200
Flesh 100-200
Shell 100-200
Flesh 44
Shell 44
Whole 4
Body 100-200
Body 100-200
Body 100-200
Shell 100-200
Whole 26
Foot 22
Body 22
Shell 22
Foot 47
Body 47
Foot 54
Body 54
Adductor muscle 27
d CFs
8.2
8.9
2.6
1
7.1
0.5
8,14
0.7,0
11
0.9
10
0.3
10-11
0.3-5
8
0
4.3-6.4
10
10-15
10
1
3
7.8
8.5
0.09
8.5
10
9.1
10.5
8.4
Comments
From sediment
From sediment
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
Sulfate form
                                      53

-------
Table Ib.  (Continued)
Organism
M. edulis
M. edulisf
M. edulis
M. edulisf
M. edulis
Crassostrea gigas 9
(oyster)
C. gigas9
C. gigas9
C. gigas9
Mya arenaria (clam)
M. arenaria
M. arenaria
Paphia philippinarum
( c 1 am )
P. philippinarum
Mya truncata (clam)J
Mytilus edulis (mussel )J
Ostrea edulis (oyster)J
Pecten maximus (scallop)J
Mytilus galloprovincialis
(mussel )
L-
M. galloprovincialis
M. galloprovincialis
Bivalve
Bivalve
Bivalve
Mercenaria mercenaria171
(clam)
Crassostrea virginicam
Body part
Pelecypoda
Retractor
Adductor
Retractor
Whole
Body
Whole
Body
Shell
Muscle
Whole
Body
Muscle
Body
Muscle
Whole
Whole
Whole
Whole
Shell
Body
Whole
Whole
Body
Shell
Body
Body
Exposure, d
(continued)
muscle 27
muscle 58
muscle 58
58
58
48
48
48
48
200
200
200
5
5
28
28
28
28
64
64
64
32
20
12
CFs Comments
9.8
7.8
8.8
12.9
9.2
7.7
9.4
9.2
6.6
4.6
3.0
10.0
7-9
3.5
2.3
1.7
1.7
0
10
3
10.5
97
0
6 Nonequilibrium
5
  (oyster)
                                      54

-------
Table  15.   (Continued)
Organism
                            Body  part     Exposure,  d
            CFs
         Comments
Gomphina melanaegis
  (c 1 am)
G_._ melanaegis1
Ranqia cuneata0
                          Pelecypoda  (continued)
                            Body              14
                           Muscle
                           Whole
14
29
6
2.3     Estuarine
Li ttorina 1 ittorina1-1
  (snail)

Octopus vulgar is13
  (octopus)
0. vulgaris
                                Gastropoda
                           Whole             28

                                Cephalopoda
                           Whole             14

                           Arms and          14
                              tentacles
           6

           6.4
a
b
c
d
e
f
g
h
i
j
k
1
m
n
o
P
Amiard-Triquet  (1975).
Ancellin and Vilquin  (1968).
Argiero et. _al_.  (1966).
Avargues _et_ a_L  (1968).
Bonotto _et _al_.  (1981).
Bryan (1963).
Cranmore and Harrison  (1975).
Harrison (1973).
Hiyama and Shimizu  (1964).
Morgan (1964).
Polikarpov (1961),  cited from Jackson e^t  aj_.  (1983)
Polikarpov (1964),  cited from Jackson _et_ _al_.  (1983)
Price (1965), cited from Jackson et _al_. (1983).
Ueda et aj_. (1978).
Wolfe and Coburn  (1970).
Suzuki et al. (1978).
                                      55

-------
Mollusca Arthropoda


100.000
10,000
o
5 1 ,000
c
o
2
c
0
o
100




10




1.0
n 1
PELECYPODA
Lab








—




~ '3k-.
ago




Sublu












O

O
0
o























CRUSTACEA
f=,«ld










••
«







Lib










O
oo
'00
CD





Sllblc











O
o
o






Uhordata






















F,»ld


O
o
o




0
o
X
<&
PISCES
Lib









,
Tjf
A
a»
«a»

*



O
o
0°0


o

oo


St«b!»
-
-



A

*
A —
A
^
™


—
A




Figure 8.  Concentration factors  for  cesium in  muscle  tissue  of  marine biota:
laboratory-derived CFs  from this  report  (o);  field-derived  CFs from Jackson et_
a_K (1983) (o)  or Noshkin (1985)  (•);  stable  element-derived  CFs from
Polikarpov (1966) (o) or Pentreath,  1977 (A).
                                      56

-------
similar to those for muscle and indicate little bioconcentration  of  cesium.
Shell CFs were lower than those for living tissues, as expected.   Comparison
of field-derived and laboratory-derived data shows that the highest  values
were determined generally in field populations (Fig. 7).

Elimination Rates

     Elimination rates of cesium have been determined for the oyster
Crassostrea gigas, the clam Mya arenaria, Gomphina melanaegis,  and Anadara
granosa, and the mussel Mytilus edulis (Table 16).  Two compartments were
identified in some species.  The biological half-life for the short-lived one
was generally a few days while that for the long-lived one was  generally a few
months.  In the octopus, cesium in the arms and tentacles, which  make up 68%
of the body weight, had a half-life of 90 d (Suzuki _et _aj_., 1978).

ARTHROPODA - CRUSTACEA

Concentration Factors

     The range of CFs of cesium for Crustacea was similar to that for other
marine organisms (Table 17, Figs. 7 and 8).  Again, some of the highest values
were obtained from Crustacea from field populations.

Elimination Rates
     The only data available for elimination rates of cesium in  Crustacea  are
for a euphausiid and a prawn.  Fowler et^ al_. (1971) found  the half-life of
1 ^7
   Cs in whole Euphausia pacifica to be 6 d.  This zooplankton had been fed
radioactive Artemia sp. nauplii.  Bryan and Ward (1962)  followed the  loss  of
            	                                     137
cesium in the prawn Palaemon serratus, which had acquired     Cs  through the
food chain.  They found an average retention in three animals of about 70% of
initial body burden after 48 h in nonradioactive water,  and  a retention of
about 45% in one prawn after 6 d in nonradioactive water.
                                      57

-------
Table 16.  Biological half-life (days) of cesium in Mollusca.'
Organism
Body part    Pool A
              Pool B
             Comments
Crassostrea gjgas
  (oyster)
Mytilus edulisc
  (mussel)
Mya arenaria (clam)(
FL_ arenaria
M^ arenaria
C_o_ virginica6
Anadara granosa
  (clam)
A_._ granosa
Clam9
Clam9
       Pelecypoda
Whole         90( —)
Whole

Whole
Body
Muscle
Whole
Whole

Whole
Body
Muscle
  7.6(49)

  3.6(75)
  3.6(77)
  3.3(65)
250(100)
  3.0(70)

620.5(100)
  3(100)
 13(100)
60(25)
41(23)
33(35)

15.5(30)
             Loss in situ
Octopus vulgaris
  (octopus)
      Cephalopoda
Whole         90(100)
a Number in parentheses is the percent of the activity in the pool
  Cranmore and Harrison (1975).
c Dahlgaard (1981).
d Harrison (1973).
e Hess et a/L  (1977).
f Patel e^^l_. (1978).
9 Price (1965)s cited from Jackson et al. (1983).
h Suzuki et al. (1978).
                                      58

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Table 17.  Laboratory-derived concentration  factors  (CFs) for cesium in
Arthropoda - Crustacea.
Organism
Crangon vulgaris (shrimp)3
Carcinus maenas (crab)3
C. maenas
C. maenas
Portunus puber (crab)
P . puber
P. depurator
P . depurator
Polybius henslowi (crab)
Cancer pagurus (crab)
C. pagurus
Corystes cassivelaunus
(crab)
C. cassivelaunus
Homarus vulgaris (lobster)0
Decapoda-Stomatopoda
Zooplankton
Zoopl ankton
Galathea squamifera
(squat lobster)
G. squamifera6
H. vulgaris
H. vulgaris
H. vuljjaris
Palaemon serratus
P. serratus
P. serratus
P. serratus
P. serratus
P. serratus
Body part
Whole
Whole
Whole
Muscle
Whole
Muscle
Whole
Muscle
Whole
Whole
Muscle
Whole
Muscle
Whole
Muscle
Whole
Whole
Muscle
Exoskeleton
Whole
Muscle
Exoskeleton
Whole
Muscle
Shell
Whole
Muscle
Whole
Exposure
d
12
7
67
67
67
67
67
67
67
67
67
67
67
28
58
11
11
150
150
150
4.2
4.2
4.2
4.2
4.2
4.2
CFs
20
4
8.5 +_ 0.6
17.7
6.6 + 1.48
13.1
6.5 + 0.0
12.0
5.2
6.0 + 1.4
11.3
4.4
11.4
4.7
19.4
12
14
12.6, 13.6
4.0, 4.2
7.6
14.9
1.5
29.2
33.9 + 2.6
10.9 + 4.5
25
25.6 + 1.6
29.5
Comments
Water, unfed
Water, unfed
Water, unfed
Food and Water
Food and Water
Food and Water
                                     59

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Table 17.   (Continued).
Organism
P. serratus
f
P. serratus
Leander pacificus^
L, pacificus^
L. pacificus^
Shrimp or prawn
Crangon vulgaris (shrimp)0
Pandalus montagui (shrimp)0
Leander serratus (shrimp)
Nephrops norvegicus
(euphausiid)
Body part
Muscle
Shell
Whole
Body
Body
Whole
Whole
Whole
Whole
Whole
Exposure
d
4.2
4.2
11
4
2
150
28
28
8
28
CFs
27.4 + 2.0
6.6 + 1.2
13.3 + 2.6
15
15
12-13
20
18
15.9
7.3
Comments
Food and Water
Food and Water
Cancer pagurus (crab)'
Whole
28
7.2
  Bonotto et _al_. (1981).
  Bryan (1961).
  Morgan (1964).
  Bryan (1963), cited from Jackson et _a_L  (1983).
  Bryan (1965).
  Bryan and Ward (1962).
  Hiyama and Shimizu (1964).
  Lemee et_ _aj_. (1970), cited from Jackson  et_ _a]_.  (1983).
                                      60

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CHORDATA - PISCES

Concentration Factors

     Considerable data are available on CFs of cesium for marine fishes
(Table 18).  CF values for fishes are similar in range to those of other
aquatic organisms (Figs. 7 and 8).  A number of studies have been undertaken
to try to understand the effect of route of entry of the cesium radionuclides
on CFs and to ascertain whether trophic enrichment occurs (higher CFs in
organisms in higher trophic levels than in those in lower trophic levels).
Data are not available that permit conclusions to be made on the effects of
feeding behavior and trophic level on CF values (see review by Pentreath,
1981).
     Factors affecting cesium accumulation that have been examined include the
addition of stable cesium and chelating agents, changes in temperature,  and
differences in body weight.  No effect on CFs of the addition of stable cesium
or of chelating agents was found (Hiyama and Shimizu, 1964).  However,  the rate
of accumulation of cesium by a number of species was found to decrease  with
increased body size and to increase with increased temperature of the water
(Morgan, 1964; Nakahara et al., 1977).
                                                  134
     A comprehensive study of the accumulation of    Cs from seawater by the
plaice and the thornback ray was conducted (Jefferies and Hewett, 1971).  For
these species, information is available on organ as well as whole body
                                                     134
accumulation.  Every organ of the plaice accumulated    Cs at a faster  rate
than that of the ray.

Elimination Rates

     Elimination of cesium in whole fish and fish muscle is relatively  slow
(Table 19).   In plaice and the thornback ray, kinetics of elimination of cesium
were evaluated from experiments that followed both the accumulation  and loss
of the radionuclide;  the biological  half-lives compared well.
                                      61

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Table 18.  Laboratory-derived concentration factors for cesium in Chordata -
Pisces.
Organism
Blennius sp. (blenny)
Blennius sp.
Blennius sp.
Micropogon undu1atusc
(Atlantic croaker)
Paralichthys dentatus (flounder)0
Acanthogobius flavimanus (goby)
Pleuronectes platessa (plaice)6
P. platessa
p
Raja clavata (thornback ray)
R. clavata6
Clupea harengus (herring)
Pollachius virens (coalfish)
P. pollachius
Mugil chelo (grey mullet)
Gadus morhua (cod)
Trisopterus luscus (whiting)
Anguilla anguilla (eel )
Scophthalamus maximus (turbot)
S. rhombus
Limanda 1 imanda (dab)
Solea solea (sole)
P. platessa
R. clavata

Body part
Flesh
Whole
Flesh
Muscle
Whole
Muscle
Muscle
Whole
Muscle
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Whole
Exposure
d
100-200
100-200
100-200
29
91
>30
800
800
800
800
28
28
28
28
28
28
28
28
28
28
28
28
28
CFs Comments
36,15
15-35
15-35
4.5 (Nonequilibrium)
9
25
20.2
10.6
2.3
3.4
9.2
4.0
3.5
2.7
2.7
2.1
1.6
2.8
2.6
2.5
2.5
2.1
0.5
  Ancellin  and Vilquin  (1968).
  Avargues  ert _a_L  (1968).
  Baptist and Price  (1962).
  Hiyama and  Shimizu  (1964).
  Jefferies and Hewett  (1971).
  Morgan (1964).
                                      62

-------
Table 19.  Biological  half-life  (days)  of  cesium  in Chordata - Pisces.
Organism
Paralichthys dentatus
(flounder)
Micropogon undulatus
(Atlantic croaker)
Blennius pholis (blenny)c
Mugil chelo (mullet)0
Pleuronectes platessa (plaice)
P. platessa
Raja clavata (thornback ray)
R. clavata
P. platessa
P. platessa6
R. clavata6
R. clavata6
Evynnis japonica (sea bream)
Helicolenus hilgendorf
(scorpionf ish)
a Number in parentheses is the
b Baptist and Price (1962).
c Fraizier and Vilquin (1971).
d Hewett and Jefferies (1978).
e Jefferies and Hewett (1971).
f Suzuki et al. (1978).
Body part
Whole
Muscle
Whole
Whole
Whole
Muscle
Whole
Muscle
Whole
Muscle
Whole
Muscle
Whole
Whole
Pool Aa
5.3(34)
34.8(35)
20-30(12)
20-30(25)
57.9(100)
139.0(100)
68.8(100)
126.4(100)
64.7(100)
120.3(100)
179.7(100)
189.3(100)
75-95(100)
75-95(100)
Pool Ba Comments
36.9(66)
94.7(61)
203 + 18(88)
154 + 24(75)
Uptake
from water
Uptake
from water
percent in the pool .
                                     63

-------
                                  STRONTIUM

PHYSICOCHEMICAl FORM

     Strontium has physicochemical  properties  similar  to  calcium  and,  like
calcium, appears mainly in  ionic  form in  water.   In  seawater, calcium  serves
as a nonisotopic carrier for strontium.   The concentration  of strontium  in
surface seawater is 7.4 mg/kg and that of calcium is 417.6  mg/kg  (Quinby-Hunt
and Turekian, 1983).  Neither strontium nor calcium  is strongly sorted by
particulate material.   The  mean Kd  recommended for use in models  of coastal
waters is 1000 and that for the pelagic waters sea is  200;  the ranges  are 100
to 5000 and 2 to 500,  respectively  (IAEA, 1985).  Because of the  low Kd  of
strontium in marine ecosystems, most  of the strontium  is found in the  water
column.

PRIMARY PRODUCERS

Concentration Factors

     The CF values of  strontium reported  for microalgae ranged from 4  to 1600
(Table 20).  A comparably wide range  was  found in field populations also
(Fig. 9).  Experiments performed  to evaluate factors affecting the uptake of
strontium by phytoplankton  showed that the uptake of strontium was proportional
to the concentration of strontium in  the  medium  (Corcoran and Kimball, 1963).
Furthermore, concentrations up to ten times the  normal  concentrations  of
strontium did not seem to affect  growth or strontium accumulation.  For
macroalgae, the upper  extent of the range of values reported was  lower than
that for microalgae for both field- and laboratory-derived  data (Fig.  9).

Elimination Rates

     No laboratory-derived  data on  elimination rates of strontium in primary
producers were found.
                                      64

-------
Table 20.  Laboratory-derived concentration  factors  (CFs)  for  strontium  in
primary producers.
Organism
Nitzschia closteriuma
Phytoplankton
Chlamydomonas minima
Carteria sp.
Carteria sp.
Diva lactuca (green alga)e
Monostroma sp. (green alga)
Sargassum thunbergii (brown alga)
Gracilaria confervoides (red alga)
Fucus serratus (brown alga)9
Ulva rigida (green alga)9
U. lactuca (green alga)9
Dictyota fasciola (brown alga)9
Padina pavonia (brown algae)9
Cystoseira barbata (brown alga)9
Corallina rubens (red alga)9
Ceramium rubrum (red alga)9
Polysiphonia elongata (red alga)9
Phyllophora nervosa (red alga)9
Green alga
Green alga
Brown alga
Brown alga
Brown alga
Red alga
Red algah
Red alga
Red alga
j n h
Red alqa
Exposure
Microalgae
24
24
Macroalgae
10
7
7
f 7
8
8
8
26
26
26
26
26
26
26
26
26
26
, d CFs
17
9
4
561
1600
0.3
6.7
6.5
5.3
40
2
1
18
19
40
4
1
1
8
0.8 + 0.0
1.0 +_ 0.0
42.1 + 2.0
25.3 +_ 3.4
6.4 +_ 0.2
1.4 +_ 0.0
3.8 + 0.2
1.3 +_ 0.0
2.2 +_ 0.4
2.3 + 0.0
Comments
Rapidly growing
Extracted from
dead plants
7 and 70 mg Sr/L
7 and 70 mg Sr/L
7 and 70 mg Sr/L
                                      65

-------
Table 20.   (Continued).
Organism Exposure, d CFs
Fucus serratus (brown alga)1 -- 40
F. serratus1 -- 30
F. vesiculosus -- 23
F. vesiculosus -- 35
Ascophyllum nodosum (brown alga)1 -- 22
Laminaria digitata (brown alga) -- 14
Chrondrus crispus (red alga)1 -- 1.7
Gigartina stellata1 -- 2.2
Ulva lactuca (green alga) -- 1.2

Comments
In dark
New growth
a Boroughs et _al_. (1957).
b Martin (1958), cited from Jackson et al. (1983).
c Polikarpov (1964).
d Rice (1956).
e Hampson (1967), cited from Jackson et al. (1983).
Hiyama and Shimizu (1964).
9 Polikarpov (1966).
h Ryndina (1972), cited from Jackson et al. (1983).
1 Spooner (1949).
                                    66

-------
           Primary Producers
                                                                              Arthropoda
                                                                                                      Chordata
10.000
1,000

100



10

,


0.
0.0
Mactoalgae
Whole
Field



0
8
o
o

'£3
QD





Lab




*
£
(
£.
s
?

•

Stable



O
O
O
o
99
«
o


0
o
0















Mictoalgae
Whole
Field


O
O
8
o
0
§
0
CD





Lab

*
*


•

»
•




Stable





0



O



Pelecypoda
Whole
Field
O
0
o



&
0



Ljb






»



Shell
Field


s
O
O





Lab





•




Body
Lab








\












Uaitco
Shell
Field

0








poda
Body
Fluid





V















Cephalopoda
Whole
Field







3


Stable









O
Cmitacea
Whole
Field




•JO

O
o





Lab




•

ac


•


e
Stable










O
0

E
Field













r~keiet
Lab





.








3n
Stable
O



























Pitcei
Whole
Field




,»

*
%
O




Lab






•


•



Stable







'-•





Skeleton
Field

O
(j
8

.







Lab









8
•


Stable
-




t



A



Figure 9.   Concentration factors (CFs)  for  strontium in marine biota:  laboratory-derived CFs from
this report  (•);  field-derived CFs from Jackson  et a]_.  (1983) (o) or Noshkin  (1985)  (•);  stable-
element-derived  CFs from Polikarpov  (1966)  (o) or Pentreath (1977) (A).

-------
ANNELIDA

     No laboratory-derived data on  CFs  and  elimination  rates  of  strontium in
Annelida were found.

MOLLUSCA

Concentration Factors

     Data on CFs of strontium in Mollusca are  available only  for Pelecypoda
(Table 21, Figs. 9 and 10).  Values are considerably  lower for soft tissues
than for the shell.  Because of the accumulation  of radioisotopes of  strontium
                                                     90
in shells of bivalves, they have been used  to  monitor    Sr contamination  in
the aquatic environment (Nelson, 1962).

Elimination Rates

     No data on elimination rates of strontium in Mollusca were  available.

ARTHROPODA - CRUSTACEA

Concentration Factors

     Limited numbers  of CFs of  strontium are available  for Crustacea  (Table 22,
Figs.  9 and 10).  However,  the  range of values  is  similar to  that for other
marine organisms.  Some of the  highest  values  were obtained from Crustacea from
field  populations. CFs of exoskeletons were higher than those of soft tissues,
and accumulation of strontium in the exoskeleton  may  account  for the  high CF
values for whole animals.

Elimination Rates

    No data on the elimination  of  strontium in Crustacea were available.
                                     68

-------
Table 21.  Laboratory-derived  concentration factors (CFs) for strontium in
Mollusca - Pelecypoda.
Organism
Mytilus galloprovincialis3
(mussel )
Crassostrea sp. (oyster)
Mercenaria mercenaria (clam)c
M. mercenaria0
Meretrix meretrix (clam)
Venerupis phil ippinarum (clam)
V. phil ippinarum
V. phi 1 ippinarum
V. phil ippinarum
V . phi 1 ippinarum
Mytilus edulis (mussel)
M. edulis6
M. edulis6

Body part
Whole
Body
Shell
Body
Muscle
Muscle
Body
Shell
Body
Shell
Body
Shell
Whole
Exposure
d
5
20
20
20
20
18
18
64
64
64
CFs Comments
3.6
1
10 Nonequi 1 ibrium
0.9
>0.7
>0.4
0.8 7 mg Sr/L
1.5 7 mg Sr/L
0.5 70 mg Sr/L
1 .6 70 mg Sr/L
0.7
6
6
a Argiero et al. (1966).
b Boroughs _et _a_L (1957).
c Chipman (1959).
  Polikarpov (1961).
                                      69

-------
10,000
1,000
100
0
y
CO
c
0
co
C
§ 10

1


0.1
n m
Mollusca
Pelecypoda
Field
-
-





—

-


_

Lab










•
*


Stable








O


O
00















Arthropoda
Crustacea
'Lab











*


Stable









88

0
O















Chordata
Puces
Field










S



Lab












•
e
Stable
-
-
—




—
O
A —
*
A
O
ox*-

Figure 10.  Whole-body concentration  factors  (CFs)  for strontium in muscle
tissue of marine biota:   laboratory-derived CFs  from this  report (•)
field-derived CFs  from Noshkin  (1985)  (•); stable-element-derived  CFs  from
Polikarpov (1966)  (o)  or  Pentreath  (1977)  (A).
                                      70

-------
Table 22.  Laboratory-derived concentration factors  (CFs)  for  strontium  in
Arthropoda - Crustacea.
Organism
Body part
Exposure,  CFs
    d
Comments
Artemia salina (brine shrimp)3
A. salina3
Tigropus californicus3
Leander sp. (shrimp)
Leander sp.
L. squillac
Krilld
Krilld
Krilld
Whole
Whole
Whole
Muscle
Exoskeleton
Whole
Whole
Whole
Whole
1
3.8
9
9
64
4-6
4-6
4-6
0.7
0.2
1
0.2
15
8
8.0 + 0.6
12.1 +; 0.9
29 + 0.9
Nauplii
Nonequilibrium
Site 1
Site 2
Site 3
  Boroughs _et _al_. (1958).
  Hiyama and Shimizu (1964).
  Polikarpov (1966).
  Tolkach and Gromov (1976).
                                      71

-------
CHORDATA - PISCES

Concentration Factors

     Laboratory-derived CFs of strontium have been obtained for both bony and
cartilagenous fishes (Table 23).  Examination of the experimental  data on
accumulation of strontium shows that almost all  the experiments were too short
in duration for steady-state conditions of uptake and loss  to have occurred.
Absence of equilibrium conditions is indicated also because the field-derived
CFs were larger than the laboratory-derived CFs  (Figs.  9  and 10).
     The effect of differing calcium and strontium concentrations  on the
occurrence of the radioisotopes of these elements in tissues as well  as  the
relative role of the food and water pathway in accumulation of strontium have
been examined.  However, the interpretation of the results  from studies  of both
of these factors is controversial.  Because the results of  these investigations
have been reviewed recently (Pentreath, 1981), a discussion of the data  will
not be included here.

Elimination Rates

     The metabolism of strontium in the Atlantic croaker  Micropogon undulatus
was investigated by Baptist et_ aj_. (1970).  The  loss was  biphasic  and the
half-lives were 1.25 d and 138 d for the short-  and long-lived components,
respectively.  The short-lived component was 21% and the  long-lived was  79% of
the total activity.  Analysis of the rates of loss from tissues indicated that
the long-lived component represented loss from bones and  scales.

                                    COBALT

PHYSICOCHEMICAL FORM

     Cobalt is commonly present in more than one chemical form in  seawater.
It can be present in ionic  form or associated with dissolved organic  material.
Cobalt may also be present  in low concentration  in the  form of cyanocobalamin
(vitamin  B  12),  which is required by many aquatic organisms  but  synthesized by
only a few.   The concentration of cobalt in surface waters  is  7  ng/kg and in
deep waters  is  2 ng/kg  (Quinby-Hunt  and Turekian,  1983).  These  authors  state
                                      72

-------
Table 23.  Laboratory-derived concentration factors (CFs) for strontium in
Chordata - Pisces.
Organism
Tilapia mossambicaa
Mugil cephalus (mullet)
Fundulus heteroclitus
(mummichog)
Rudarius ercodes0
R. ercodesc
Pterogobius elapoidesc
P. elapoides0
Acanthogobius flavimanus (goby)c
A. flavimanus0
Trachurus japonicus
T. japonicus0
Pleuronectes platessa (plaice)
P. platessa

Body part
Whole
Whole
Muscle
Muscle
Vertebra
Muscle
Vertebra
Muscle
Vertebra
Muscle
Vertebra
Whole
Flesh
CFs
0.3
5
0.1
0.03
0.5
0.04
1.4
0.04
0.7
0.06
1.5
1.0
0.15
Comments

Euryhal ine
Young
Nonequilibrium
Nonequi 1 ibrium
Nonequil ibrium
Nonequi 1 ibrium
  Boroughs _et _a]_. (1956).
b Chipman (1959).
0 Hiyama and Shimizu (1964).
d Templeton (1959), cited from Jackson et al.  (1983).
                                      73

-------
that cobalt is maximum in concentration in surface waters  and, with  depth,  is
positively correlated with the labile nutrients and negatively correlated with
dissolved oxygen.
     The K, for cobalt is higher than that for cesium and  strontium.   The mean
K, recommended for use in models of coastal  waters is 100,000 and  that for
 d
pelagic areas is 3,000,000;  the ranges are 20,000 to 500,000 and 50,000 to
5,000,000, respectively.   Because of its high  affinity for particulate
material, cobalt is found primarily in the particulate fraction of the water
column.

PRIMARY PRODUCERS

Concentration Factors

     Although the data available on CFs of cobalt determined under field and
laboratory conditions in  microalgae are limited,  CFs have  been determined for
many different macroalgae (Table 24, Fig.  11).  The range  of CFs for macroalgae
is similar for stable-element- and radionuclide-derived values.  These results
indicate that steady-state conditions of uptake and loss of cobalt were
probably reached in the laboratory experiments.
     The marine alga Dunaliella bioculata  was  found to concentrate  Co
rapidly, and the CF determined was considerably lower in the presence  of
increased concentrations  of  stable cobalt  (Kirchmann et_ ^1_., 1977).  The
accumulation of   Co by Ulva sp. is reported to be dependent on light;  the
CF was 2.5 times higher in algae grown in  the  light than in the dark.   These
results indicate that accumulation of cobalt may be an active rather than a
passive process,

Elimination Rates

     Few data are available  on the biological  half-life of cobalt  in primary
producers.  The biological half-life of cobalt in Ulva pertusa was determined
to be 10 d (Nakahara et_ al_.,  1975).   The loss  of  60Co from Halimeda incrassata
was found to be fit best  by  a one-compartment  model;  the half-life was 9.4 d
(Spies et_al_._,  1981).   Mattsson et_ al_.  (1980)  reported a biological half-life
of 60 ^ 15 d for Fucus vesiculosus that was  collected from waters  around the
Barseback Nuclear Plant.
                                      74

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Table 24.  Laboratory-derived concentration factors (CFs) for cobalt in
primary producers.
Organism
Dunaliella bioculata3
Phytoplankton
Porphyra sp. (red alga)3
Acetabularia mediterranea
(green algae)
A. mediterranea
A. mediterranea
Ulva lactuca (green algae)3
U. pertusa0
U. pertusa0
Sargassum thunbergii (brown alga)
A. mediterranea
A. mediterranea
U. pertusa6
Laminaria japonica (brown alga)
Eisenia bicyclis (brown alga)6
Q
Undaria pinnatifida (brown alga)
Hizikia fusiforme (brown alga)6
Sargassum thunbergii (brown alga)
Chondrus ocellatus (red alga)6
Q
Ahnfeltia paradoxa (red alga)

Body part
Exposure
Microalgae
Whole 27
Whole
Macroalgae
Whole 19
Whole 2
Whole 21
Whole 25
Whole 19
Whole 22
Whole 22
c Whole 22
Whole 7
Chloroplasts 7
Whole 20
Whole 20
Whole 20
Whole 20
Whole 20
6 Whole 20
Whole 20
Whole 20
, d CFs Comments
100
326
314
187
410
228
612
380 August
>17 April
420
200-400
18-25
439
138
34
120
127
2574
833
290
  Bonotto  et _aj_.  (1978).
  Martin  (1958),  cited from Jackson _et _a_L  (1983).
  Hiyama  and Khan (1964).
  Kirchmann et^ a]_.  (1977).
  Nakahara et  al. (1975).
                                      75

-------
                   Primary Producers
                                                       Mollusca
                                                                                         Arthropoda
                                                                                                           Chordata
        100.OOO -
        10,000
         1.000 -
          100 -
           10 -
          0.1
Macioale*
Whole
Field
O
O

-








_

-
Lab


«


t
t
t



;
*



Stable




0
§
O
0
o

0
0

...





















Microelgae
Whole
Lab

































Pelecypoda
Whole
Lab






*



.,




Stable


A
A


A







00
Shell
Lab





•
•

•0
**
••

•
•
«
Body
Field





•









Lab






i


*

.



Stable





A
A
A







A


















Giutropod*
Body
Stable






A

A
























Cephalopoda
Whole
Stsble





A
A
A





A
A



















Cruitacae
Whole
Fi«ld



«











Lab





»





•



Stable




-,
O
A
0
•i
A


























Crustacea
Exoikeleton
Lab












e


Stoble






A




A





















PllCtl
Whole
Lab













t

Stable
-
-

—

Li
g

U



-

~
            1 -
Figure  11.   Concentration factors  (CFs)  for cobalt  in marine biota:  laboratory-derived  CFs from this  report (•);
field-derived CFs from  Jackson e_t  al_.  (1983) (o) or Noshkin (1985)  (•);  stable-element-derived CFs from
Polikarpov  (1966) (o),  Shimizu et _a_L  (1970) (A).

-------
 ANNELIDA  -  POLYCHAETA

 Concentration Factors

     CF values of cobalt have been determined for only a few polychaete  worms.
 For Arenicola marina, CFs of 10 for the coelomic fluid,  1000 for  the  blood,  and
 25 for the  digestive tract were determined (Triquet, 1973).   For  whole A.
 marina, a CF of 335 was obtained (Amiard-Triquet, 1975).  For Neanthes
 diversicolor, uptake of cobalt from water, food and water, and sediment  was
 investigated (Ueda et al., 1977).  The CFs obtained from worms exposed to
 radioactive cobalt in the water was 6^1, in the food and water  was  7,  and  in
 the sediment was 0.045 and 0.055.  Young (1982) investigated the  accumulation
 by Neanthes virens of   Co released into seawater from the corrosion  of
 neutron-activated stainless steel.  The average CF from  water during  months  6
 to 13 of the exposure was 343 ± 123 and from sediment was 2.25 ±  0.36.

 Elimination Rates

     The  loss of   Co from Nereis japonica was followed  for  24 d  (Ueda _e_t
 al., 1977).  There was a rapid loss of   Co during the first 2 to 3 d and
 then the rate of loss was slower.  The half-life obtained for the slower
 compartment was 37 d.

 MOLLUSCA

 Concentration Factors

     CF values of cobalt in Mollusca are presented in Table  25 and Figs. 11  and
 12.  The highest values were obtained in the experiments of  longest duration.
 Comparison of the field- and laboratory-derived data shows that the range of
 values for the body was different (Fig. 10).  These data indicate absence of
 steady-state conditions for most, if not all, populations exposed under
 laboratory conditions.
     Investigations have been made of the importance of  food and  water in the
 uptake of cobalt by Mollusca.  Nakahara et al. (1976) showed that the
 absorption of   Co by some Mollusca depended on the species  of algae  on
which they were fed;  the percent absorbed varied from 26 to  47.   Amiard  (1978)

                                      77

-------
Table 25.   Laboratory-derived concentration factors (CFs) for cobalt in
Mollusca.
Organism
Scrobicularia plana (clam)
S. planaa
Macoma balthica (clam)a
M. ba1thicaa
Mytilus edulis (mussel)
Crassostrea gigas (oyster)
C. gigasc
C. gigas0
C. gigasc
Mya arenaria (clam)
• d
M. arenaria
M. arenaria
Phaphia philippinarum (clam)e
P. philippinarum6
P. philippinarum6
P. philippinarum6
Venerupis philippinarum (clam)
V. philippinarum
V. philippinarum
Mytilisepta virgatus^
(mussel )
M. virgatus^
M. virgatus^
M. virgatus^
M. virgatus^
M. virgatus9
Mytilus edulis (mussel )h
M. edulish
Body part
Pelecypoda
Body
Shell
Body
Shell
Whole
Whole
Body
Muscle
Shell
Whole
Body
Muscle
Shell
Viscera
Shell
Viscera
Viscera
Muscle
Shell
Body
Body
Shell
Shell
Muscle
Muscle
Body
Shell
Exposure
d
35
35
35
35
26
48
48
48
48
179
179
179
10
10
10
10
22
22
22
40
40
40
40
40
40
15-35
15-35
CFs
32
76
22
53
30
300
51
41
610
220
82
100
35
10
3
2
9.2
>7
36
1.4
13
0.7
11
0.8
8.5
140
190
Comments
No carrier
No carrier
Carrier added
Carrier added
Trisglycinato
complex of Co
Ionic Co
Trisglycinato
complex of Co
Ionic Co
Trisglycinato
complex of Co
Ionic Co
CoCl2,200 ppm
CoCl0,200 ppm
                                     78

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Table 25.   (Continued).
Organism
             Exposure
  Body  part      d
           CFs
           Comments
M_._ edulis1
M^ edulis1
_M_._ edul i s
M_._ edul i s
M. edulis1
M. edulis
Macoma inquinata1-1
M. inquinata
  Body
  Shell
  Body
  Shell
  Body
  Shell
  Whole
  Whole
 60
 60
 60
 60
 60
 60
390
390
 135 j^ 40  Nonequilibrium
  40 +_ 18  Nonequilibrium
 155 _+ 30  Nonequilibrium
  75 +_ 30  Nonequilibrium
 120 + 20  Nonequilibrium
  52 + 15
 244 + 95
Nonequi1ibrium
From water
0.48 + 0.1 From sediment
Octopus or squid
Cephalopoda
 Muscle
 30
  15
  Amiard-Triquet  (1975).
b Bonotto _et aj_.  (1981).
c Cranmore and Harrison  (1975)
d Harrison (1973).
e Hiyama (1962).
f Hiyama and Khan  (1964).
9 Nishiwaki _et a_L  (1981).
h Shimizu _e_t _a]_.  (1970).
1 van Weers (1973).
J' Young (1982).
k Nakahara et al.  (1979a).
                                      79

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                         Mollusca
                                      Arthropoda
Chordata

10,000

1,000


3
u
CO
c
o
CO
c
8
o 10
1
0.1
0.01
Pelecypoda
Field

-

-


-


-
-
-
Lab






•


s
•

Stable





§

O
















Crustacea
Lab









•


Stable


O





















Pisces
Field
OO
O
I









Lab










*

Stable

-

-
A
A
^-
O
cmo
'j^yu
A*A
0 _
-
-
Figure 12.  Concentration factors  for  cobalt in muscle tissue of marine  biota:
laboratory-derived CFs from this report  (•);  field-derived CFs from Jackson  et
aj_. (1983) (o); stable-element-derived CFs from Polikarpov (1966)  (o)  or
Pentreath (1977) (A).
                                       80

-------
reported that the CFs obtained from short-term exposure to  cobalt  in  the  water
were 300 to 400 times greater than those from food.   When accumulation  had
occurred over a 2-month period, CFs from the water pathway  were  7.6 times that
from the food pathway.
     The accumulation of ionic cobalt and cobalamin  by the  abalone Haliotis
discus was compared (Ueda et_ aj_., 1981).  They reported that  the distribution
of cobalt in the liver was different for the two forms of cobalt.

Elimination Rates

     Metabolism of cobalt has been investigated in both clams and  oysters
(Table 26).  Generally, elimination was several months in duration  in the long-
lived compartment.  Pentreath (1973a) investigated the uptake of cobalt in
various tissues of Mytilus edulis.  When the radionuclide was administered in
the water, half-lives ranged from 4.7 d in the foot  to 17.7 d in the  adductor
muscle.  He concluded from his analysis of stable-element data that
accumulation of radionuclides from water was minor relative to that from  the
food.
     The accumulation and loss of   Co by the octopus Octopus vulgaris was
followed by Nakahara et a1_. (1981).  The distribution of the   Co  in octopuses
that had accumulated the radionuclide from the food  differed  from  that  in
octopuses that had accumulated it from the water.  The biological  half-life of
  Co calculated from the long component of the excretion curve of  whole body
radioactivity was approximately 200 d for the organisms reared in  labeled
seawater and was 300 d for those administered labeled food.

ARTHROPODA - CRUSTACEA

Concentration Factors

     CF values of cobalt for crustaceans are presented in Table  27.   It is not
known whether the considerable variability shown is  due to  differences  in
species or the absence of equilibrium conditions.   Most of  the cobalt was
present in the exoskeleton and would be lost from  the animal  upon  molting.
     Amiard and Amiard-Triquet (1977) followed the uptake of  cobalt from  food
and seawater in the crab Carcinus maenas.  The CF  resulting from cobalt in the
water was 5.8 times that from food.

-------
Table 26.  Biological  half-life (days)  of  cobalt  in  Mollusca  - Pelecypoda.
Organism
Scrobicularia plana (clam)
Crassostrea gigas
(oyster)
C. gigasc
r • c
C . gigas
C. gigas
Mya arenaria (clam)
M. arenaria
M. arenaria
Crassostrea virginica6
(oyster)
Body part
Whole
Whole

Body
Muscle
Shell
Whole
Body
Muscle
Whole

Pool Aa
2-4(~)
220( — )

130(-)
300 ( — )
100(-)
120(100)
240(100)
180(100)
35(100)

Pool Ba
30-57( — )
40(-)

7(~)
12(-)
35(-)
—
—
—
__

  Number in parentheses  is  the  percent of total activity in the pool.
  Amiard-Triquet and  Amiard (1976a, b).
  Cranmore and Harrison  (1975).
  Harrison (1973).
  Hess et al.  (1977).
                                     82

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Table 27.  Laboratory-derived  concentration  factors  (CFs) for cobalt in
Arthropoda - Crustacea.
Organism
Crangon vulgaris
(shrimp)
C. vulgaris3
Carcinus maenasa
(crab)
Leander pacificus
(shrimp)
L. pacificus
L. pacificus0
L. pacificus0
L. pacificus0
L. pacificus0
Clibanarius virescens0
(hermit crab)
C. virescens0
d
Crangon crangon
Body part
Whole
Exoskeleton
Whole
Whole
Whole
Muscle
Exoskeleton
Muscle
Exoskeleton
Whole
Whole
Whole
Exposure, d
12
12
7
19
19
15-35
15-35
15-35
15-35
15-35
15-35
30
CFs
37
100
30
20
5
5
18
4
14
520
57
13
Comments
No carrier
Carrier added
No carrier
No carrier
CoCl2, 200 ppm
CoCl2, 200 ppm
CoCl2, 200 ppm
CoCl2, 200 ppm
Water
a Bonotto _et jj_. (1981).
b Hiyama (1962).
0 Shimizu et _al_. (1970).
d van Weers (1975).
                                     83

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Elimlnation Rates

     Little information is available on the biological  half-life of cobalt in
Crustacea.  Amiard-Triquet and Amiard (1976b)  found that the rate of loss  of
  Co from the fast compartment was related to  the frequency of feeding.   No
data on half-lives were given.  When the shrimp Crangon crangon was fed
  Co-labeled mussel flesh and then the loss of activity followed, two
components of loss were identified (van Weers, 1975).   The  short-lived
component had a mean biological half-life of 1.2 d and  accounted for about 80%
of the initial activity.  The long-lived component had  a half-life of about
10 d and represented about 20% of the activity.

CHORDATA - PISCES

Concentration Factors

     Data on CFs of cobalt in marine fishes are limited (Table 28).   Values are
considerably lower than those of Mollusca and  Crustacea.  Comparison  of field-
derived stable-element and laboratory-derived  radionuclide  CF  values  shows that
the range of the stable-element values is more than an  order of magnitude
higher than that obtained under laboratory conditions.   The accumulation of
cobalt from food and water was compared in  the yellowtail (Seriola
quinqueradiata)  (Nakahara _ejt  _aj_.,  1979b;  Suzuki _et al.,  1979).   After the  fish
were exposed for a 7-d period, the percentages of    Co  in tissues  were
different for the two pathways, but the significance of the pattern  of the
differences was  not apparent.
                         ro
     The accumulation of   Co by the thornback ray was  followed for 84 d
(Pentreath,  1973b).  Data on  organ CFs  show a  high  value of 2.2  in the gills
and a low value  of 0.3 in the muscle.   This investigator concluded that intake
from water played only a relatively minor role in  the accumulation of cobalt
by the ray.

Elimination  Rates

     The biological half-life of cobalt has been  determined for a number of
species (Table 29).  The elimination of cobalt was  followed in  the Atlantic
croaker Micropogon undulatus  after intraperitoneal  injections  (Baptist et  al.,

                                      84

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Table 28.  Laboratory-derived concentration  factors  (CFs) for cobalt in
Chordata - Pisces.
Organism
Girella punctata3
G. punctata3
Chasmichthys gulosus
C. gulosus
C. gulosus
Brevootia tyrannusc
Body part
Whole
Whole
Whole
Whole
Whole
Whole
Exposure,
22
22
22
22
22
16
d CFs
>5
>2
4.5
5.2
2.5
7.1
Comments
No carrier
Carrier added
July, small size
Oct., small size
Medium size
Nonequilibrium
(post-larvae menhaden)
Sebastes nivosusc           Whole
  (rock fish)
Evynnis japonica0           Whole
  (sea bream)
E. japonicac                Muscle
Seriola quinqueradiatac     Whole
  (yellowtail)
S. quinqueradiata0          Muscle
Paralichthys o1ivaceusc     Whole
  (flounder)
P. olivaceusc               Muscle
 20

 62

 62
131

131
120

 20
4.2    Nonequilibrium

4.8

0.5
1.2

0.3
5.5

1.5
  Hiyama (1962).
  Hiyama and Khan (1964).
  Nakahara et al. (1979b).
                                     85

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Table 29.  Biological half-life (days) of cobalt in Chordata - Pisces.
Organism
Body Part  Pool Ac
              Pool Bc
              Comments
Micropogon undulatus
 (Atlantic croaker)
Blennius pholisc
 (blenny)
Mugil chelo0
 (grey mullet)
Evynnis japonica
 (sea bream)
r   .     -  d
E. japonica
Seriola quinqueradiata
 (yellowtail)
^_._ quinqueradiata

Paralichthys o1ivaceusc
 (flounder)
£_._ olivaceus

Pleuronectes platessa6
 (plaice)
?_._ platessa6

Raja clavata6
 (thornback ray)
R. clavata6
Whole
Whole
Whole
Whole
Muscle
Whole
Muscle
Whole
31(100)
203±18(88)
154±24(75)
Whole      28.9( —;

Muscle     38.5( — ;
23.9(-)

53.3( —)

49.5(--)

63.0(~)
Whole      65(100)

Muscle     120(100)
180(100)
Muscle     189(100)
           Intraperitoneal
           injection
20-30(12)  Loss after uptake
           from water
20-30(25)  Loss after uptake
           from water
           Loss after uptake
           from water
           Loss after uptake
           from water
           Loss after uptake
           from water
           Loss after uptake
           from water
           Loss after uptake
           from water
           Loss after uptake
           from water
           Accumulation from
           water
           Accumulation from
           water
           Accumulation from
           water
           Accumulation from
           water
  Number in parentheses  is  the percent  of  total  activity in  the  pool.
b
  Baptist et a/L  (1970).
C Fraizier and Vilquin (1971).
d Nakahara &t_ _aJL  (1979b).
6 Jefferies and Hewett (1971).
                                     86

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 1970)  and only one compartment was  identified compared to two compartments for
 the  other radionuclides that were examined.  These investigators state that
 more compartments  might have been found if  loss of the cobalt had been
 followed  for  a longer time.  The accumulation by the common goby Acanthogobius
 flavimanus  of  Co that had been incorporated into Nereis japonica was
 followed  (Kimura and Ichikawa, 1972).  A triphasic pattern of loss was found
 after  a single meal of worms had been consumed.  The absorption of
 sediment-bound  Co was studied after oral  administration of encapsulated
 sediment  (Koyanagi  et al_., 1978); loss was found to be biphasic.

         APPLICATION OF  CONCENTRATION FACTOR AND ELIMINATION  RATE  DATA

 Concentration  Factors

     CFs  for  radionuclides in marine organisms are, in general, higher in
 primary producers  than in marine invertebrates, and fish  usually have  lower
 CFs  than  invertebrates (see also reviews by Coughtrey and Thome,  1983a,  b).
 Examination of  the distribution of laboratory-derived CF  values for a  specific
 group  of  organisms  shows  that the spread of the values may range over  several
 orders of magnitude (Pentreath, 1977, 1981).  For a given species, the CF is
 dependent on  whether the  analysis was made on the whole organism,  on the
 eviscerated body,  on soft tissues only, or on selected organs or tissues.
 Comparison  of  laboratory- and field-derived CFs shows that there is better
 agreement between  the data sets for some groups than for  others.  It is
 expected  that  better agreement would occur for organisms  or body parts that
 have short elimination times than for those that have long ones, and for  those
 organisms or  body  parts where surface adsorption reactions predominate rather
 than for those  where transfer across membranes and uptake by internal  tissues
 is required.
     The distribution of  radionuclide concentrations in environmental  media
 and the distribution of the resulting CFs calculated from them generally  are
 highly variable and exhibit a skewness.  This is readily  demonstrated  by  the
 plots of CFs in this report.  Such CF values are not well represented  by  a
 normal distribution, but they are well approximated by a  lognormal
distribution (i.e., the  values  of the logarithms of the CFs appear to  be
normally distributed).   Such lognormal distributions for  radionuclide
                                      87

-------
concentration data and CF values have been described previously by others, and
procedures for the statistical treatment of the data have been given (Gilbert,
1979, 1983).
     Because CF values exhibit such a wide range of values, it is difficult to
select a single value to use in dose-assessment models.   An approach used
frequently in the past has been to select a conservative value;  however,  this
practice is currently considered to be a poor procedure  except in efforts to
protect the public in advance of an actual release of radioactivity.  The
current approach used by modelers to predict the movement of radionuclides
through ecological systems is to stress the use of stochastic models, wherein
the actual distribution of data sets is considered and results are specified
in a probabilistic nature.  This more realistic approach has several important
advantages.  The most important is that model outputs represent  a more
realistic assessment of the inherent variability of natural  systems, and  the
regulator is presented with a probability distribution.   From this
distribution, a desired degree of conservatism can be selected or the dose
being calculated can be presented in terms of a probable value and an
appropriate statement of uncertainty.
     To apply these concepts, however, it is necessary to specify a
distribution of values for each of the input parameters  used in  a model and to
propagate uncertainties throughout the model.  Therefore, some of the CF  data
in this report have been examined to specify the distributions of values.   Of
the radionuclides and groups of organisms discussed in this  review,  I  am
considering only the field-derived CFs for plutonium and cesium  in fishes and
molluscs because they are the only ones with a reasonable body of data.
     The two-parameter lognormal  distribution is described mathematically by

     f(x)  = [l/(a V^f)]  exp[-(ln x - y )2/(2a2)J
                 •/                     J       J
              X > 0,  - oo >  y^ > co, a^ > 0 ,

                2
where u   and a    , the two parameters of the distribution,  are the true mean
       J      j
and variance, respectively, of the transformed variate y = In x  (Gilbert,
1983).  The distribution can be described  also by the  true geometric  mean
[exp(uy)]  and true geometric standard deviation  [exp(a )].  Such  distributions
have several  useful  properties including  the following:
                                     88

-------
      •   The  product of m independent lognormal variates is also a lognormal
         variate.  This is a very useful property in multiplicative food-chain
         models.
      •   The  ratio of two lognormal variates (x/y) is also a lognormal  variate.

If the several variates are not independent, then in the calculation  of the
variance, the correlation between the variates must also be considered
(Gilbert, 1983).  The second point above is important in consideration  of  the
utilization of CF values.
      Analyses were performed on the values, cited by Noshkin (1985),  of field-
derived CFs for plutonium and cesium in fishes and molluscs.  The  analyses
included plotting the values on lognormal probability paper to examine  the
assumption of lognormality.  If a straight line fitted the data reasonably, a
lognormal distribution was assumed; all of the CF values analyzed  appeared to
be reasonably well represented by a lognormal  distribution. A  probability  plot
of the CF values for plutonium in fish muscle is shown in Fig.  13.  Analyses
were  performed also to provide data on the median and on the mean,  variance,
and central percentage interval (plus or minus one standard deviation)  with the
assumptions that the data were (1) normally distributed and (2)  lognormally
distributed. The arithmetic mean was always larger than the median  or the
geometric mean (Table 30).
      Examination of the data on the central percentage confidence  intervals
shows that the values obtained, assuming a normal distribution,  are of  little
value for analysis of uncertainty because negative numbers are  obtained (the
standard deviation is larger than the mean). It is also clear that  the  true
geometric standard deviations are large.  These large true geometric  standard
deviations could be attributed to many causes.   First, the data are not
homogeneous; they were obtained by a variety of investigators  on a  variety of
specimens.  Second, there may be systematic errors between investigators whose
data  are represented in the data base.  And finally,  the biological and
chemical  systems measured may in fact have very large variability.
      In general, the following steps are suggested in the selection of
parameters to be used in models.
     •   Perform a probability plot of the data to determine whether the data
         are best represented by a normal  or lognormal distribution.
     •   Determine the mean,  standard deviation,  and  confidence intervals  for
         the appropriate distribution.

                                      89

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        1000
         0.1 -
          0.14
                                                                              2

                                                                              I
                                                                              c
                                                                              o
                                                                              '£


                                                                              e
0.62  0.23  0.67   16    31    50    69   84   93   97.7  99.4


                 Cumulative probability (%)
Figure  13.   Concentration  factors for  plutonium in  muscles of fish.  The


arithmetic  mean is 77  (sigma = 220), and the geometric mean is 8.9


(sigma  = 8.7).
                                         90

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Table 30.  Values obtained from statistical  analyses  of  CFs,  assuming  a normal distribution and a lognormal
distribution.
Organism Number
Fish
Muscle 48
Bone 22
Liver 17
Pelecypods
Soft tissues 16

Fish
Muscle 35
Pelecypods
Soft tissues 10
Normal distribution
Median Mean S.D.a Central
65% interval
Plutonium
9.5 68 220 -152 to 288
77 160 180 -20 to 340
64 1400 2400 -1000 to 3800

420 650 870 -220 to 1600
Cesium

47 54 31 23 to 85

41 380 680 -300 to 1100
Lognormal distribution
GMb S.D. Central
68% interval

9.5 7.8 1 .2 to 74
64 5.4 12 to 350
130 14 9.3 to 1800

340 3.0 110 to 1000


45 2.0 22 to 90

74 7.6 10 to 560
Central
95% interval

0.2 to 530
2.4 to 1,700
0.7 to 23,000

40 to 2000


12 to 180

1.4 to 3900
   S.D., standard deviation.
   GM,  geometric mean.

-------
     ®   Critically review the data for  systematic  or  other  biases  to  derive
         the most appropriate values for the particular  application.

     Single values of CFs for plutonium  and  cesium  in  fish muscle and  soft
tissues of molluscs to be used in  models have been  selected  previously by
others (Table 31). Comparison of those values to  the means given in this
report, which were  calculated from the  data base from Noshkin  (1985),  shows
that most are within reasonable agreement, considering the variance of  the
data.  However, the range of values given differ  considerably from  the
confidence intervals calculated.

Elimination Rates

     It is important in determining the  elimination of radionuclides that (1)
the initial pulse labeling of the  organisms  be performed over a length  of time
sufficient to label long-lived compartments  and  (2) the  loss be followed long
enough to identify long-lived compartments.   If data on  long-lived compartments
are not available, then wrong conclusions can be  drawn about the retention of
radionucl ides and their potential  for transfer to man.   For example, recent
seasonal  data from Mussel  Watch program  (Goldberg _et _a_L , 1978) showed  that  50%
of the plutonium and americium were eliminated within  3  to 10 weeks.  The
predictions that might be made as  to when contaminated mussels might be safe
to ingest after a period of depuration would be considerably longer if  the
Guary and Fowler (1981) data were  used than  if the  Goldberg _et _a_L  (1978) data
were used.

                               ACKNOWLEDGMENTS

     The  author thanks Dr. Lynn Anspaugh for his  assistance  in the writing of
the section on "Application of Concentration Factor and  Elimination Rate Data"
and for his critical  review of the report.
                                     92

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Table 31.  CF values for use in models  to  predict  the  dose to man or aquatic
organisms from the release of radionuclides  into marine  environments.
Organism


Fish
Muscle
Mol luscs
Soft tissues
Thompson et
(1972)


3.5

100b
al. IAEA
(1985)
Plutonium

40 (0.5 to 100)a

3000 (500 to 5000 )C
This report
Mean GM


68 9.5

650d 340d
Fish
   Muscle
Molluscs
   Soft tissues
30
Cesium

   100 (10 to 300)

    30 (10 to 50)C
54
                                      3801
45
  Numbers in parenthesis are ranges.
  Invertebrates.
  Molluscs except cephalopods.
  Pelecypods.
                                      93

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                                   TECHNICAL REPORT DATA
                            (Please read Instructions on the reverse before completing}
 • REPORT NO.
_EPA_520/l-85-015
'. TITLE ANDSUBTITLE
 Laboratory-Determined Concentration  Factors and
 Turnover Rates of  Some Anthropogenic Radionuclides  in
 Marine Vertebrates  and Invertebrates
                                                            3 RECIPIENT'S ACCESSION NO.
                                                            5. REPORT DATE
                                                              July 1935
                                                            6. PERFORMING ORGANIZATION CODE
                                                                    I
  \UTHOR(S)
                                                            B. PERFORMING ORGANIZATION REPORT NO
 F.  L. Harrison
 PERFORM
           ORGANIZATION NAME AND ADDRESS
 Environmental  Sciences Division
 Lawrence Livermore National  Laboratory
 Livermore,  California  94550
                                                            10. PROGRAM ELEMENT NO.
                                                            11. CONTRACT/GRANT NO.

                                                              IAG No. AD89-F00070
12. SPONSORING AGENCY NAME AND ADDRESS
 Office of Radiation Programs
 Environmental Protection Agency
 401 M St.,  S.W.
 Washington,  D.C.  20460
                                                            13. TYPE OF RE PORT AND PERIOD COVERED
                                                              Final
                                                            14. SPONSORING AGENCY CODE

                                                              ANR-461
 5 SUPPLEMENTARY NOTES
16. ABSTRACT
       Literature is reviewed  and summarized with regard to concentration factor
       values  and biological elimination rates  determined in laboratory  experiments
       for  several anthropogenic radionuclides.   Comparison is made with concentration
       factors measured  in  situ in the marine  environment.
                                KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                                              b. IDENTIFIERS/OPEN ENDED TERMS  C.  COSATI Held/Group
8. DISTRIBUTION STATEMENT
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                                                 Unclassified
                                                                            NO. OF PAGES
                                              2O SECURITY CLASS 11'liu
                                                 Unclassified
   Form 2220-1 (Rev. J-/7)   PREVIOUS EDITION 15 O BSC
       7U.S. GOVERNMENT PRINTING OFFICE: 1986-621-735/60520

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