*
NATIONAL ENVIRONMENTAL RESEARCH CENTER
        RESEARCH TRIANGLE PARK
           NORTH CAROLINA

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On the cover:   The  main building of the National
Environmental  Research Center, Research  Triangle
Park,  North Carolina, is composed of research labo-
ratory wings connected by  nodes and  describes  a
gentle arc  around a  central courtyard.   This  view
shows the  inner  courtyard from one  of the inter-
connecting nodes.

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                ANNUAL REPORT

                       1973

NATIONAL ENVIRONMENTAL RESEARCH CENTER
           RESEARCH TRIANGLE PARK
                NORTH CAROLINA
             U.S. ENVIRONMENTAL PROTECTION AGENCY
                Office of Research and Development
               National Environmental Research Center
                Research Triangle Park, North Carolina

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Note:    Mention  of trade names or  commercial
products in  this  publication  does not constitute
endorsement  or recommendation  for  use  by the
Environmental Protection Agency.

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EPA has a clear mandate to carry out the environmental statutes en-
acted by Congress .  .  . In addition, I believe that EPA has a broader
responsibility  to  help  define,  articulate,  and give leadership to  the
environmental aspirations of our society." Russell Train—First speech
as Administrator, delivered before the National Press Club in Washing-
ton, D.C., September 18, 1973.

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                         PREFACE
     The Environmental Protection Agency, as with other Federal  organ-
izations,  receives  direction  from  legislative mandates passed by Congress
and approved by the President.  Important then is an understanding of how
well  the  purpose of this direction is achieved. This determination can best
be made  by reviewing programs in relation to the appropriate legislation,  In
this Annual  Report for  1973 attention is focused on the research activities of
NERC-RTP  and  their relationship to specific legislative acts applicable to
NERC-RTP- Thus, in presenting a summary of our research accomplishments
during  1973, the Report illustrates  the  responsiveness of this research to
Congressional desires. We hope too, that in reading the Report you will  under-
stand better the role of Congress and the  Executive Branch in establishing an
environmental policy and the action taken by a  Federal agency to fulfill the
intent to  this policy. Comments on the Report and our activities are welcome.
                                      John F.  Finklea, M. D.
                                      Director, NERC-RTP
                                                          n>

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                         TABLE  OF CONTENTS
EXECUTIVE SUMMARY .   .         ...                     	     1

INTRODUCTION	       ...            	           7

  Mission  .     .     .  .                      . .     	      	    g
  NERC-RTP Research Program      	         ...             .  .             11

LEGISLATIVE MANDATES	          ....         .       ...   15

SPECIAL FEATURES     	             ...         ...           	    23

  Automotive Oxidation Catalysts ......         .        ......          25
  Energy and the  Environment         	                .     .       ....   27
  Substitute Pesticide Chemicals   .                                                       30

RESEARCH ACTIVITIES          .       	     ...                     33

  Special Studies Staff  .....                  .            .       .        .35
  Human Studies  Laboratory  ...              .             ...          47
  Experimental Biology Laboratory     .             .          ......        .55
  Pesticides and Toxic Substances Effects Laboratory       .  .              .  ,       ....   65
  Chemistry and Physics Laboratory.  .                            ......      75
  Quality Assurance and Environmental Monitoring Laboratory      ...              .       .91
  Meteorology Laboratory   ...              .      ,          ...       .       . ,     105
  Control Systems Laboratory .                          ......                 115

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EXECUTIVE
SUMMARY

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EXECUTIVE
 SUMMARY
   THE ENVIRONMENTAL PROTECTION AGEN-
cy's National Environmental Research Center at Re-
search Triangle Park, NC, (NERC-RTP) constitutes one
of the  largest multidisciplinary research  groups  in
existence concentrating its efforts on developing the
bases  for improving the environment  of the United
States.  Basic research and development programs  at
NERC-RTP encompass air pollution, pesticides pollu-
tion, and radiation  pollution; a special studies staff
performs diverse technical  investigations.  This sum-
mary provides a brief discussion of the  program areas,
cites some of the major accomplishments during the
period  of this  report,  and  indicates the direction  of
future research.
                                                                             Air  Pollution
Lamp method is used to analyze sulfur content of
gasoline collected by National Fuels Surveillance Net-
work.
   Air pollution research and monitoring projects en-
compass a wide variety of scientific disciplines ranging
from the elucidation  of the effects of pollutants on
human health to the evaluation of devices for measur-
ing pollutant concentrations in the ambient air.
   In the evaluation of measurement methods, NERC-
RTP Laboratories conduct a continuing program to
establish definitive  requirements and test  procedures
to be used  in determining whether new or different
methods of sampling  and analyzing the ambient air
produce valid, legally acceptable data.  Acceptable
procedures  may then be designated as "equivalent"
methods. (Equivalent methods  provide the same de-
gree  of measurement accuracy as the "reference"
methods  given in  the regulations for  primary and
secondary ambient  air quality standards.)  In further-
ance of this project,  specific performance specifica-
tions  and  test  procedures  for  measuring carbon
monoxide, ozone, and sulfur dioxide were tested for
workability and technical adequacy by NERC-RTP
technicians  and by  a private, independent  contractor.
Reference materials (samples of known composition)
were supplied to participants in collaborative testing
of reference methods  for measuring ozone and beryl-
lium;  significant  progress was  also made  in the de-
velopment of reference materials for ambient nitrogen
dioxide measurements.
   During the year,  NERC-RTP began the preparation
of guidelines for the development of regional quality
assurance programs for use with the reference methods
for new stationary sources; and with the reference
methods for two hazardous pollutants, mercury and
beryllium.  Also,  reference  samples were  developed
for use in quality control  programs of measurements
of sulfur dioxide, carbon monoxide, and particulates
in ambient air.
   Reference methods used to characterize emissions
were  improved  for Category  I and II  new source
performance standards.  (Category  I sources include
Executive Summary

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steam electric power plants, cement plants, municipal
incinerators, sulf uric acid plants, and nitric acid plants.
Category II sources include petroleum refineries, pri-
mary lead  and copper  smelters,  and asphaltic con-
crete plants.)   Performance criteria were developed
for extractive and in-situ  instrumentation for deter-
mination of compliance with  sulfur oxide,  nitrogen
oxide, and opacity standards for a number of Cate-
gory I sources.
   X-ray fluorescence methods for use in analyzing
a number of possibly hazardous materials were de-
veloped, and improved sampling and analysis  methods
for polycyclic organic matter, asbestos,  and  mercury
are being evolved.  Particular  research emphasis was
placed on assessing levels  of mercury that may have
an adverse effect on human health.
   Several special studies were conducted by NERC-
RTP  at the request of  EPA's Office of Air  Quality
Planning and  Standards to determine  the  ambient
concentrations of significant pollutants—one of many
instances of  technical assistance being provided to
other  EPA components and to  State  air  pollution
control agencies.
   Operational responsibility for  the Continuous Air
Monitoring Program (CAMP) stations in  Philadelphia,
PA,  Denver,  CO,  and Chicago,  IL, was transferred
from NERC-RTP  to the  EPA  Regional Offices in
these cities.   The transfer involved personnel  and
resources and included responsibility for  the direction
of the  National Air  Surveillance Network  (NASN)
monitoring program for total suspended particulates,
sulfur dioxide, and nitrogen dioxide.
   In the area of  air quality simulation modeling,
both  for  predictive  and  diagnostic purposes,  the
User's .Network of  Applied Models of Air  Pollution
(UNAMAP),  a  centralized computer facility, began
operation.  This network  provides nationwide access
by  any user, public or  private, to  standardized  and
consistent  model  arrays  to  estimate concentration
dispersion fields  for  six different  source,  receptor,
dispersion,  and topographic settings. Developmental
work continued on improving  and evaluating the sen-
sitivity  of  simulation models for reactive  and non-
reactive species of pollutants for  both local  and
regional applications.
   Several important field investigations were under-
taken during the year including a study in Denver, CO,
conducted in^cooperation  with the  EPA Region VIII
Office and the Colorado State Air Pollution  Control
Office, to clarify the nature and source of the Denver
"Brown  Cloud";  a  study  in  Houston,  TX,  and
Phoenix, AZ, on  photochemical oxidant air pollut-
ants; and a study in St. Louis, MO, on photochemical
oxidant and  sulfur oxide air  pollutants.   Also in/
St. Louis, in preliminary experiments relating to the
Regional Air Pollution  Study (RAPS), an  intensive
aerosol characterization program was  begun  during
the summer, and the difference in the solar radiation
budget between a rural and urban site was investigated.
Preliminary evaluation of the data indicates that the
city of St. Louis received about 6.5 percent less solar
radiation than in its rural surroundings,  presumably
because of the extinction of sunlight by air pollutants.
RAPS, a major  NERC-RTP  research  program, is de-
signed to  improve  the  techniques  for  developing
least-cost  air pollution  control strategies for urban
areas.
   NERC-RTP established a comprehensive  and in-
tegrated  program  to study the  effects  of  aerosol
composition on visibility.  This program included
field studies to examine specific instances of visibility
reduction  caused by aerosols, a project to develop a
theoretical model  of visibility  degradation,  a study
of the effects of humidity on aerosols and visibility,
and a study  of aerosol formation as a  function of
reactant concentration.   Construction of an  aerosol
generation facility was also planned.
   Statistical,  numerical, and  experimental  studies
were  undertaken  to investigate  the effects of air
quality  on  meteorological  parameters  and clima-
tology—and  to assess the  effects of meteorology and
climatology  on  air quality.  Wind tunnel modeling
and cloud and  rain-chamber  techniques were  used
to  determine the scavenging efficiency of precipita-
tion  on  atmospheric  aerosols,  a  process  bearing
heavily on the problem of acid rains.
   The Community  Health  and  Environmental  Sur-
veillance System (CHESS) program, a major NERC-
RTP  project that relates air  quality to human health
effects, was continued in 31 neighborhoods in 6 sec-
tions of the country—the interstate area of  New York-
New  Jersey; the  state   of  Utah; and the cities of
Chattanooga, TN, Birmingham,  AL, Charlotte,  NC,
and Los Angeles, CA.  The health indicator  used  in
the program included chronic respiratory disease  in
adults,  acute  lower  respiratory  disease  in children,
frequency of daily asthma  attacks, pulmonary func-
tion tests of school children, cumulative residue of
pollutants in body tissues,  and daily aggravation of
symptoms in individuals with pre-existing heart and
lung  disease.    Results  of the CHESS program for
1971-1972 for New York and the Southeastern areas
revealed  that,  with  respect to  respirable-size  par-
ticulates,  the  implementation  of plans  to   improve
air quality in the areas would provide obvious  benefits
to the study populations. Analysis of data and prep-
aration of reports  pertaining to nitrogen  dioxide and
oxidantsfor 1971-1972  was  begun for the Los Angeles
basin and for Chattanooga.  Preliminary results from
laboratory  studies of controlled exposure of  humans
to  oxidants indicate that ambient air concentrations
of  the pollutant in a number of  cities may be suffi-
ciently  high  to  cause  indentifiable chromosomal
aberrations.  The report Health Consequences of Sul-
                                                                            AIS1NUAL REPORT 1973

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fur Oxides: A Report from CHESS,  1970-1971 was
published in May 1974.
   Measurable progress has been achieved  in develop-
ing the technology required to  control air pollution
from stationary  sources in a timely and cost effective
manner. On the pressing  problem of fine particulate
(matter less than 3 micrometers in diameter) control
technology, potential areas of  improvement of  con-
ventional devices have been defined, and laboratory
testing of new concepts in detection and removal has
been accomplished.  Among the "conventional" de-
vices,  field tests  show that properly designed and
operated electrostatic precipitators can be more  than
90 percent efficient on a mass basis  in collecting all
particle size fractions down to about 0.01 micrometer
in diameter. Experimental work by NERC-RTP to aid
in selecting optimum fabric filter cleaning methods
was described in a report issued in early 1974.  Test
programs  were  initiated  to  evaluate  two new par-
ticulate  control  devices, the sonic agglomerator and
the  steam-hydro  scrubber; feasibility  studies  were
completed on the use of charged droplets and  con-
densation  effects to improve fine  particle collection.
   The control  of sulfur  oxides  has been a major
problem of concern  in efforts to improve air quality.
The flue-gas-cleaning demonstration  projects that are
presently underway  are expected to provide removal
efficiencies ranging from  60 to 97 percent for these
pollutants.  The technical feasibility  of removing in-
organic sulfur from coal was proven in  both laboratory
and bench-scale tests;   design  of a pilot-plant-size
operation  has begun.  Support for  coal gasification
and conversion processes and for versions of f luidized-
bed combustion of  coal  and residual oil  to  reduce
emissions  (particularly for steam and power genera-
tion) has continued.
   Techniques were  developed for the reduction of
nitrogen oxides  emissions from combustion processes
by as  much  as  50 percent in commercial coal-fired
boilers.   Commercially  feasible means of  reducing
carbon   monoxide,  hydrocarbons,  and  particulate
emissions from  coke  ovens by 90 percent were also
demonstrated.
   The  NERC-RTP intramural  capability  to support
control technique development  programs took a sig-
nificant step forward  with the installation of the first
aerodynamic  test facility specifically  designed for
studies requiring large gas volumes (up to 15,000 cfm),
carefully controlled  velocity  profiles, and test mate-
rials of  known  chemical composition.  A research
prototype  lidar  (laser-radar) system  designed specifi-
cally for the  measurement of particulate emissions
from stationary  sources  was obtained, and a  new
long-path irradiation chamber system capable of the
resolution  of fractional  parts per  billion of ambient
air pollutants began operation.
   Improved  optical  measurement  instrumentation
has been developed for determining concentrations of
regulated pollutants emitted by on-the-road vehicles.
Extensive research  was  accomplished on  sampling
techniques for particulate emissions  from light-duty
vehicles using leaded and non-leaded  fuels in vehicles
with and without catalytic devices.
   Analyses  of some  1500 samples of fuels and fuel
additives were  completed, and  some certified fuel
standards were developed. NERC-RTP participated
in a cooperative  test of the trace element content of
fuels with approximately 50 public and private labora-
tories using various measurement methods.
   Currently, more than 325 additives used in gasoline
have been registered in a number of chemical classi-
fications. Detailed characterization of vehicle exhaust
products resulting from  combustion of fuels with
and  without additives and of  products eminating
from  catalytic control devices and  alternate  power
systems has resulted in a reassessment of the  public
health benefit related to the use of oxidation catalysts
on mobile sources because of  the attendant increase
in  levels  of  potentially hazardous, non-regulated
emissions.
   Scientific summary documents, which contribute
to the scientific knowledge base necessary for adminis-
trative decisions regarding the need  for control of a
pollutant and indicate the strategy necessary to achieve
that control, were initiated or  completed for a num-
ber of pollutants.  This  documentation of pollutant
characteristics leads to the issuance or revision of air
quality  criteria,  which are compilations of the latest
available information on  the sources, prevalence, and
manifestation  of recognized air  pollutants.   During
Fiscal Year  1974 for example, intramural review of
the effects  of  sulfur  oxides  on vegetation   led  to
revision  of  EPA's Air Quality  Criteria for  Sulfur
Oxides,  which led to  a  revision of  the ambient air
quality  standards for that pollutant.  By arrangement
with the National Academy of Sciences (NAS), review
documents for vapor-phase organic matter, chlorine,
selenium,  copper,  zinc,  arsenic,  and the platinum-
group heavy metals are being developed.  With respect
to the timely review of criteria documents (a require-
ment of the Clean Air Act of 1970), NAS is also pre-
paring reviews on  carbon monoxide, photochemical
oxidants, nitrogen oxides, and fine particulate matter.


            Pesticides Pollution

   A significant  portion  of NERC-RTP  pesticide  re-
search is directed toward evaluating the health effects
of pesticides and their residues on laboratory animals
and ultimately on humans.  For example, high con-
centrations of an experimental organophosphate  in-
secticide was  found  to  cause irreversible paralysis
Executive Summary

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in animals.  The significance to humans of this finding
will  be evaluated  using  a newly  developed,  more
sensitive procedure for determining low-level organo-
phosphate exposure.
   It was also found that,  among pesticides tested in
animals using  an electroencephalograph, carbanyl
caused changes  in brain wave patterns and changes in
behavior in primates at a concentration that approxi-
mates  the  incidental or background  exposure  levels
experienced by humans.  The  significance of  these
findings with respect to  humans is under active  inves-
tigation.
   During  Fiscal Year 1974, all  pesticides laboratory
functions  were  consolidated  at  IMERC-RTP  from
Perrine, FL, and Chamblee, GA.  This transfer meant
that  not only were better accommodations provided
and  more efficient  and economic operations  made
possible, but a significant element of  increased safety
for  operating personnel  and for experimental animal
colonies was also achieved.
             Radiation  Pollution

   Research activities at NERC-RTP included the in-
vestigation  of both ionizing radiation and nonionizing
electromagnetic  radiation effects  using  laboratory
animal models.  Ionizing radiation research programs
were confined to tritium and  krypton-85, two major
effluents from the  reprocessing of nuclear fuel.  Non-
ionizing  radiation  research (part of a multiagency
control program)  investigated potential detrimental
effects of environmental exposure to radio and micro-
wave frequencies.
   Unique  exposure facilities  for the investigation of
biological effects of exposure  to radio frequency and
microwave  radiation were constructed at NERC-RTP.
These  facilities were  used in studies  that demon-
strated the production of chromosome aberrations in
mammalian cells  caused  by  microwave  radiation.
Future efforts will include research on the teratologic
and neurobiologic effects of  nonionizing radiation.
   Humans are exposed to environmental tritium from
conception throughout their  life span.  A long-term
dose/response study of female rats continuously ex-
posed  to tritiated water (HTO) over the gestation
period and of their off-spring demonstrated harmful
effects at concentrations  approaching existing stand-
ards for  exposure  of human  populations  to tritium.
Research into  the  harmful effects of krypton-85 on
laboratory  animals was  continued with  attention
directed toward its cancer-causing properties.
   Research on the health effects of synergistiopqjlut-
ants  was also continued.  A study of the long-term
effects of continuous  exposure to  lead  combined
with tritium revealed a tendency toward birth anom-
alies in laboratory animals.


                   Special  Studies

   During the period of this report, NERC-RTP con-
tinued its involvement  in a  host of international ac-
tivities in cooperation with agencies such as the World
Health Organization, the World Meteorological Organi-
zation, the Organization for Economic Cooperation
and  Development, and the North  Atlantic Treaty
Organization and with  individual countries  such  as
France, Poland, Pakistan, the United Kingdom, and
India.  A broad spectrum of involvement has resulted
in technical  assistance  programs  as well as scientific
research in the fields of health effects research, source
monitoring,  pollutant dispersion  modeling, and con-
trol technology.  Cooperative research agreements in
specified areas of environmental  pollution included
bipartite  projects  with  the  Federal  Republic  of
Germany, Japan, and  the  Soviet Union  and  a tri-
partite project with Sweden and Japan.
   NERC-RTP research capabilities were also focused
on environmental problems related to  the desire  to
again  become  self-sufficient as  a nation  in energy
production.   Substantial  financial   resources  were
allocated to the study  of the impact of alternative
power production strategies on  human health—par-
ticularly  regarding the  increased levels of sulfates,
nitrates,  and total respirable particulates emitted  as
certain fuels are  burned.   A major objective  is the
development of more precise measurements of human
exposure  in situations  of  normal activity  to permit
the  establishment of  relationships  between  health
effects and  air monitoring  data  and  to allow  closer
coordination between  field epidemiological efforts
and controlled laboratory studies.
   Extensive support in resources and data was pro-
vided to the Energy Research and Development Pro-
gram  Task Force, a concerted, cooperative effort by
Federal agencies to plan the Nation's energy future.
A series of model  environmental research and de-
velopment activities were  formulated  by EPA  to
coincide with  the development  of new energy pro-
duction technology. The models allow for an- iterative
process of  environmental  assessment  and  control
technology  development from the  early  stages  of
new technology conception through final demonstra-
tion and commercial application.
                                                                          ANNUAL REPORT  1973

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INTRODUCTION

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INTRODUCTION
  THE ENVIRONMENTAL PROTECTION AGENCY
conducts its activities under the auspices of several
legislative mandates.  Of these, four give direction to
EPA's research programs carried out by the National
Environmental Research Center at Research Triangle
Park(NERC-RTP):

  • Clean Air Act.
  • Federal Insecticide, Fungicide, and Rodenticide
     Act.
  • Federal Food, Drug, and Cosmetic Act.
  • Public Health Service Act.

  This  Report,  in  describing  the Center's research
activities during 1973, relates how these programs are
supportive of the mandates expressed in these Acts.
Accordingly,  the  legislative mandate  portion of the
Report  summarizes these  Acts  and the  NERC-RTP
programs directly supportive of them. The last section
of the  Report describes the NERC-RTP's scientific
program in detail and its relationship to specific sec-
tions of the Acts.   The Executive Summary briefly
discussed the highlights of the  Center's activities in
1973.  This section continues  with a general discus-
sion of  the Center—its mission, research  program,
and summary of resources.  The Report covers the
activities of the Center for the period January through
December 1973.  A supplement to the Report will be
published listing  the publications of the Center Staff.
                                                                                       Mission
The National  Environmental  Research Center  at
Research  Triangle Park, North Carolina, is a highly
specialized facility in which multi-discipline research
programs directed toward solving environmental prob-
lems are conducted.
   The National Environmental Research Center at
Research Triangle Park  has the primary responsibility
within the Environmental Protection Agency for the
conduct and management of research and related ac-
tivities pertaining to  air pollution.   In addition, the
Center has responsibilities for carrying out  research
in the fields of pesticides and radiation.  In general,
Agency research related to environmental media other
than air is performed by EPA at other National En-
vironmental Research Centers. Also, in the interest of
maximizing the  scientific  resources  available to the
Agency as  its  research and development operations
evolve, responsibilities  for  research  in  air pollution
effects with direct implications for non-human life and
in the economic costs  to the nation have gradually
been transferred to those other Centers.
   NERC-RTP  is the corporate successor to preceding
Federal research organizations that have evolved as a
result  of  the  nation's  growing  concern about  air
pollution over the last  20 years.  Accordingly, the
focus of NERC-RTP's objective generally is  reflected
in the stated purpose of the Clean Air Act; its research
is tied to the statutory  mandates of  that Act as well
Introduction

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as of newer  legislation pertaining to pesticides and
radiation.
   The  underlying purpose  stated by the Clean Air
Act  is  to  protect and enhance  the  quality of the
nation's air resources  so  as  to  promote  the public
health  and  welfare and the productive capacity of its
population.  With  this now broader  mandate, the
Center's mission can be paraphrased so  as to protect
and  enhance the quality  of  life  and  the  productive
capacity of the nation's population.  Recognizing the
overwhelming technical problems and economic costs
to the  nation posed by a purpose of this lofty dimen-
sion, and to ensure that solutions advanced for dealing
with those  problems would be meaningful.  Congress
has stipulated other action purposes for the Act, the
aims of which  are to  accelerate  a  national research
and  development program and to provide  technical
assistance  to  state  and  local  governments.   The
mechanisms mandated by Congress for  achieving the
nation's environment-related goals rely heavily  on
the use of standards to be promulgated by the Agency.
Such  standards are  applicable   specifically to the
offending  sources and are  designed to  limit their
emissions   in  accordance  with  appropriate  environ-
mental  goals.   To ensure  relevancy for the  emission
standards,  particularly where the problem is general
and widespread, standards reflecting the environmen-
tal goals are required to be established by the Agency.
The standards  limiting emissions from the sources
must reflect  both the cause-and-effects relationships
and  the technological feasibility of their implementa-
tion.   The scientific  knowledge  necessary  to define
the  environmental  goals, the  establishment  of  the
role of emissions as they relate to these  goals, and the
engineering capability to  ensure availability of con-
trol  technology at reasonable costs in  societal, cul-
tural,  and  economic  consequences are essential  to
the mission of NERC-RTP
   The conduct of research  supporting the develop-
ment of a  reliable monitoring and surveillance capa-
bility—for  following  the  progress in  attaining  the
environmental  goals  and  ensuring compliance with
the  source standards—is  ancillary to  the  Center's
mission.   Scientific  knowledge  necessary  to define
the environmental goals includes an ability to assess
the impact of environmental  pollution on health and
welfare parameters as  the following objectives relate
to this need:

   •  Identification of the health and welfare indica-
     tors of environmental pollution.
   •  Identification  of the  chemical   and  physical
      nature of the environmental pollutants responsi-
      ble for adverse effects.
   •  Development and application of  measurement
     technology to establish pollution  levels and de-
     fine exposure patterns.
   •  Establishment  of  dose-response  relationships
      and the mechanism of the pollutant action  on
      the receptor.

   To  define the  relationships between  polluting
sources  and the  environmental exposure pattern, the
Center's  mission includes  the following  objectives:

   •  Development  and application of  identification
      and measurement  technology  to characterize
      the  chemical  and  physical nature  of  source
      emissions to the environment.
   •  Establishment  of the patterns of  movement of
      pollutants  in the environment and  the  role of
      environmental factors in their transport.
   •  Definition  of the  nature  and  expense  of the
      chemical  and physical  alterations that  attend
      the movement of pollution through the environ-
      ment.
   •  Development  and  validation of  methods for
      simulating  environmental exposure patterns and
      predicting  optimum control strategy.

   The engineering capability to control  the emissions
of  environmental  pollutants  involves the following
Center objectives:

   •  Characterization of pollutants.
   •  Development of laboratory and  pilot-scale  tech-
      niques and hardware for eliminating or minimiz-
      ing emissions.
   •  Construction of plant-scale demonstration  proj-
      ects  to assess the  effectiveness  of control
      techniques.

   Surveillance  and  monitoring  objectives  relate  to
the development and  application  of the following
parameters:

   •  Field-worthy techniques for large-scale popula-
      tion surveys to ascertain the benefits resulting
      from  the  control  of  environmental  pollution
      and to determine the soundness  of the stand-
      ards upon  which the controls are based.
   •  Measurement methodology for  monitoring the
      impact of  pollution controls on environmental
      exposure patterns.
   •  Measurement methodology for monitoring com-
      pliance  with  emissions standards and  surveil-
      lance for new pollutants resulting from control
      operations.

   A  major  function of the Center is the  documenta-
tion of the scientific and engineering knowledge result-
ing from the conduct and management  of research
related to the above objectives to provide information
for policy decisions at the Agency level.
10
                                                                             ANNUAL  REPORT  1973

-------
                              NERC-RTP

                Research  Program

   The  National  Environmental Research  Center  at
Research Triangle Park conducts research and related
functions necessary for the fulfillment of the primary
mission  of  the  Environmental  Protection Agency.
This mission is to protect the public health and wel-
fare by the establishment and enforcement of environ-
mental quality standards. The research  necessary for
the development and promulgation of those standards
is the responsibility of the Agency's Office of Research
and Development of which the NERC-RTP is a major
component.   Research,  and its auxiliary undertaking
of  environmental  surveillance,  is essential   to an
appreciation   of  the  complex and  variable  factors
upon which environmental improvement depends.
   Effective and rational  standard-setting and enforce-
ment require  sound and relevant data on  pollutants
that are  being introduced  into the environment and
on  their  impact on ecological stability, human health,
and other factors important to the well-being  of our
society.  Another obligation of research and develop-
ment is to provide to the  public and private sectors
the technological know-how to comply with  regula-
tory statutes.  All research and technological advance-
ment studies  are conducted with the expectation  of
application  in  problem  solving.  Specifically, NERC-
RTP has the  overall responsibility  for the direction
and conduct of EPA's research and development pro-
grams related  primarily  to effects of air pollutants on
health, and to the understanding of the physical and
chemical  processes  operating  during  the  emission,
transport and transformation, and reception  stages
of  the air pollution cycle.  These programs  are an
integral part  of  EPA's  closely coordinated total re-
search  program that strives to achieve  a synthesis  of
knowledge from the biological, physical, engineering,
medical,  and  social sciences that can be interpreted
in terms of  total human and environmental  needs.
   The NERC-RTP  research program  is in direct re-
sponse to the language and  intent of several Congres-
sional mandates,  specifically the Clean  Air Act (and
amendments).  The Public  Health Service Act; the
Food,  Drug,  and  Cosmetic  Act;  and  the Federal
Insecticide,  Fungicide,  and Rodenticide  Act.   The
activities of five  of the Center's  eight major units
(i.e., seven Laboratories and  the Special Studies Staff)
are  undertaken exclusively, however, under the au-
thority of the Clean Air  Act.  Results of the Center's
research  on  the impact and  the cause-effect relation-
ships  of  pollution  problems  provide  a  range  of
knowledge necessary in the establishment of standards.
The research development of  pollution  control tech-
nology provides  pollutant  emitters with  the  means
for  compliance with  air quality  standards,  and the
Center's  monitoring  capability  provides  a check  on
compliance with the standards.
   NERC-RTP conducts research on a broad  environ-
mental basis to provide EPA with a sound scientific
basis  for  control  of  environmental  pollutants that
adversely affect human health and welfare.
   These programs emphasize  the  following  major
research activities:

   •  Exposure and Source of Exposure—These  ac-
      tivities include development and standardization
      of  techniques for measurement of pollutants,
      both at their source and in the ambient  environ-
      ment.
   •  Effects of Exposure—This work  includes quan-
      tification of  the effects of exposure to  environ-
      mental  pollutants on both  health and welfare
      (including the  development  of techniques for
      assessing effects).
   •  Stratgey—This  research includes  development
      of predictive models for environmental  levels of
      pollutant emissions,  reflecting  transportation
      and removal processes.
   •  Prevent/on of Exposure—Activities  in this area
      include development of cost-effective  control
      technologies.
   •  Pollutant   Characterization—Efforts   include
      preparation  of  briefing reports, scientific sum-
      mary documents, and criteria documents.

   The  development  and  standardization  of tech-
niques for the measurement of  pollutants  both  at
their  source  and  in  the  ambient environment are
necessary  for  accurately defining  the exposure and
its source. Standards and regulations cannot be estab-
lished until the extent and  source of an exposure are
identified.   At the  Center,  techniques are  being
developed  and standardized for  defining both  air
quality and emissions.  Emphasis will continue to  be
placed on gathering valid air quality and related data
and on developing (refining) methodology for measur-
ing  pollutants.  The  chemical and physical transfor-
mations  that  pollutants  undergo from source  to
receptor  in  the atmosphere are also  being  studied.
Specialized monitoring and technical assistance serv-
ices are provided  to  EPA Regional Offices and local
air  pollution control  agencies in  their endeavors  to
identify pollutants and their sources.   The nation-
wide  fuel  surveillance  network  is operated to assess
the"  potential   impact of  emission  products from
various fuel components and from various emission
control  devices on atmospheric- reaction processes.
Exposure of various materials to pollutants is also an
important aspect of this research area. Environmental
samples are analyzed for a variety of  trace metals
and  other  pollutants,  requiring  development and
Introduction
                                               11

-------
                                                                                              ENVIRONMENTAL PROTECTION AGENCY
                                                                                          NATIONAL ENVIRONMENTAL RESEARCH CENTER
                                                                                           RESEARCH TRIANGLE PARK, NORTH CAROLINA
                                                                                                  ASSISTANT ADMINISTRATOR FOR
                                                                                                 RESEARCH AND DEVELOPMENT, EPA
c
>
I-
30
m
T>
O
30









NERC
•RTP
DIRECTOR


1 1 1
HUMAN STUDIES
LABORATORY
^

EPIDEMIOLOGY BRANCH




BIO-ENVIRONMENTAL
MEASUREMENT BRANCH

B10-EHVIHONHEMTAL
LABORATORY BRANCH

CLINICAL STUDIES
BRANCH



EXPERIMENTAL BIOLOGY
LABORATORY
-
-
-



BRANCH





MOLECULAR BIOLOGY
BRANCH



NEUROPHYSIOLOGY AND
BEHAVIORAL RESEARCH
BRANCH

-
TECHNICAL STUDIES
BRANCH

PESTICIDES AND TOXIC
SUBSTANCES EFFECTS
LABORATORY
-


CHEMISTRY BRANCH

TOXIC EFFECTS BRANCH

BIOCHEMISTRY AND
PHYSIOLOGY BRANCH















SCIENTI
s

PROGRAM COORDINATION
STAFF


CHEMISTRY AND PHYSICS
LABORATORY
-




METHODS BRANCH


EMISSION MEASUREMENTS
RESEARCH BRANCH


1
1C ADVISORY
TAFF


1 "
CONTROL SYSTEMS
LABORATORY




ATMOSPHERIC CHEMISTRY
AND PHYSICS BRANCH





~

-





BRANCH

S

GAS CLEANING AND
METALLURGICAL PROCESSES
BRANCH

CLEAN FUELS AND
ENERGY BRANCH

P RTCU












QUALITY ASSURANCE
AND ENVIRONMENTAL
MONITORING LABORATORY

-
METHODS STANDARDIZATION
AND PERFORMANCE EVALUATION
BRANCH

-
ANALYTICAL CHEMISTRY
BRANCH




BRANCH












METEOROLOGY
LABORATORY

-
REGIONAL AtRPOUUTIDN
STUDIES BRANCH

-




MODEL DEVELOPMENT
BRANCH


BRANCH





BRANCH
NOVEMBER 1174
CO
vj
w

-------
standardization of monitoring equipment for specific
elements.
   It  is  important that standard methodology  and
adequate quality control be used to ensure the  pro-
duction  of unimpeachable data and to maximize the
validity  and  comparability  of those data.  Once the
exposure to  harmful  substances and  the sources of
exposure are established,  one major  building block
has been completed in the foundation of knowledge
needed for making far-reaching national decisions on
environmental control.
   Another   body of knowledge important to  EPA
in establishing and  enforcing standards is the research
concerned with  the manner in which environmental
pollutants (singly or in combination)  cause specific
undesirable   health effects.   This  research includes
animal  studies,  human  clinical  studies,   and  epide-
miological studies  on  human  populations.   Major
emphasis is  placed on  the collection of sufficient
information  for  formulating environmental control
strategies and thus providing  bases for  establishing
national emission standards for pollutants or  source
categories that  endanger  human  health  or welfare.
   The Community Health  and Environmental  Sur-
veillance  System (CHESS) is a national  program of
standardized epidemiologic studies organized  within
the past 3 years. The  program is designed to measure
environmental  quality  as it  relates to chronic  and
acute  health indicators in  sets of communities repre-
senting exposure gradients to common air  pollutants
including particulates,  sulfur oxides, nitrogen oxides,
and  photochemical oxidants.  The CHESS program
is essential in evaluating existing environmental stand-
ards, in obtaining health  intelligence for new controls,
and  in  documenting the health benefits of air pollu-
tion control.
   Clinical research is  being conducted in  the area of
exposure effects to obtain data  on gaseous and  par-
ticulate air pollutants  relevant to the development of
standards for the  protection of human  health  and
welfare. These studies are  supportive of the standard-
setting processes in the following ways:

   •  Validating data from human studies.
   •  Providing clues to new human studies.
   •  Indicating the potential harmful effects of  new
      pollutants.
   •  Ascertaining  the adequacy  of  safety margins
      through interaction studies.

   A  specific research  area in the study of pollutant
effects on human health and welfare is the research
pertinent to providing data necessary for the intelligent
assessment of the hazards to human health  of exposure
to pesticides, toxic substances, substitute chemicals,
and combinations of these with each other and with
other environmental factors.  To obtain  these data,
toxicity studies are conducted in which various animal
species are used as models.  Methods for measurement
of human exposure to pesticides and toxic substances
are developed and improved, and a quality assurance
program   is  conducted to  ensure  the accuracy  of
analytical results.  The  studies are concerned with
identifying  pesticides,  their  metabolites, and any
adverse  effects on  normal  biological  functions.  In
these subject areas, research provides data needed  by
the Agency  in meeting its legally mandated responsi-
bilities in registering,  labeling,  setting of tolerances
for, and limiting the misuse of pesticides.
   Results of the Center's research  on the  effects
from  pollutant exposure are used in formulating and
revising  environmental quality criteria.  The epide-
miologic  studies  have been  oriented toward defining
environmental hazards and  providing data on which
to base  standards.  Biological research is designed  to
detect, define, and quantify the effects of environ-
mental pollution.  Collectively, the data generated  by
the Center's research on  exposure effects  form a
major part of the  information system that the Agency
uses to set and enforce standards.
   Relevant to the Agency's  need to make control
decisions  is the information derived from the meteor-
ological  aspects of air pollution, including theoretical
and  experimental studies of the physical properties
that affect  the transport, diffusion, transformation,
and  disposition   of air pollutants in  and  from the
atmosphere.  Through this  research, techniques and
methods  to  forecast potential air  pollution episodes
are improved.  Analytical diffusion models are de-
veloped  to predict the temporal and spatial distribu-
tion of  air  pollutants; they are also useful for pre-
evaluating proposed  air pollution  control strategies.
Studies  are also conducted  on the  effects  of  air
pollutants on the geophysical processes of weather
and climate as well as on  the energy  balance of the
earth-atmosphere system.  The Center's research pro-
gram  also includes development  of remote-sensing
techniques for measuring meteorological  parameters
in urban areas.
   Chamber and  field studies are used to investigate
physical and chemical  characteristics, transformations,
and effects on materials of emissions of sulfur oxides,
carbon monoxide, nitrogen oxides, hydrocarbons and
other organics, and their  role in producing sulfates,
nitrogen   dioxide, nitrates,  ozone,  organic  aerosols,
and other finely  divided particulate materials  in the
atmosphere.   Because the  consequences as well  as
the fate of environmental pollution can be anticipated
from  this and other  information, the Agency can
develop strategy  to be  used in  its program of estab-
lishment  of enforcement standards.
   The Center's  fourth  major area  of  emphasis, pre-
vention   of  exposure,  can  only  be  accomplished
through the development  of the technology required
Introduction
                                               13

-------
to control air  pollution sources in a timely and  cost-
effective manner.  The Agency does not stipulate the
control  technology to be used to meet  the standards
it has set; however, the Agency is required by law to
publish  control  technique documents  before it sets
air  quality  standards.  In  other  words,  EPA  must
identify the means of achieving a standard before  it
sets the standard.  Thus, much research is needed to
develop control  techniques that reflect  the best  avail-
able technology.  A large part of the Center's  research
effort is concerned with the conduct, direction, and
management of engineering research,  development,
and demonstration programs leading to the abatement
of air pollution from major stationary sources.  Labo-
ratory activities encompass development and improve-
ment  of  control  devices such as  scrubbers, filters,
and electrostatic precipitators; complete effluent gas-
treatment processes; combustion  methods and equip-
ment;  fuel  preparation  technology; and associated
sampling and  analysis instrumentation  systems.  Im-
proved  control technology must be developed if new
source  performance standards are to  have  their in-
tended  effect  and hazardous  pollutants are  to be
controlled.
   Another  important element of control in  the area
of exposure prevention is the Fuel and  Fuel Additive
Registration   program.    The  program  consists of
registering information  on the chemical composition,
purpose of  use, and  recommended  concentration of
additives used in motor gasoline that is introduced into
interstate commerce.  Fuel and  fuel additive manu-
facturers are required to provide  usage data quarterly
for registered  additives as well as information concern-
ing the mechanism of action, effects on exhaust com-
position,  and toxicity of the resultant  exhaust  prod-
ucts, if known.  There are also protocols to assess the
effect of fuel components on control device perform-
ance, which will  result in  information to allow the
control or prohibition of fuel components or additives
pursuant to the 1970 Clean  Air Act Amendments in a
time  frame to ensure public  safety and  satisfactory
performance of  advanced automotive control  systems.
   A major effort  in the Center, which results  from
the  previously  described research  programs, is the
preparation of  briefing reports,  scientific summary
documents, and criteria documents that are  required
by the Clean Air  Act Amendments.   According to
the law, the Administrator  is  required  (from time to
time but as soon as practical) to  develop  and issue to
the States such criteria of  air quality as  in his  judg-
ment  may  be  requisite  for  the protection of the
public health and welfare.  Such criteria shall reflect
the latest scientific knowledge useful  in  indicating
the kind  and  extent  of all  identifiable effects  on
health and welfare  which may be expected from the
presence of an air pollution agent.
   Pollutant characterization  is an attempt to define
the biologic effects  of  specific air  pollutants  on
humans, animals,  and  vegetation, as  well  as  non-
biologic effects such as modification of visibility and
deterioration of materials.  Characterization also in-
cludes gathering qualitative and quantitative informa-
tion on the sources, form(s),  reactivity, methods of
collecting and  quantitating,  and strategies for con-
trolling pollutants.  In  promulgating standards, the
legally  defensible  basis must  include scientifically
sound assessment of comprehensive scientific data as
reported in  criteria documents.  Associated position
papers are also required to identify the need for addi-
tional  research for producing adequate criteria for
issuing  or  revising standards.   Position papers (or
scientific  summary  documents) are  also  developed
for non-criteria pollutants to indicate the need for
control and to recommend control strategy.
   The  effort  of  NERC-RTP  in  this  area consists of
collecting,  reviewing,  evaluating,  comparing,  sum-
marizing,  and  interpreting pertinent information and
literature  to  prepare  criteria  documents,  briefing
reports, and scientific  summary  documents on non-
criteria pollutants.   In  this  preparation,  the  data
generated  by the  entire research program of the Cen-
ter converge with  all  other  available literature and
research and form the  basis needed to produce scien-
tifically sound documents.   The  Center   contracts
with  authoritative  sources—one being  the National
Academy  of Sciences—to review the information that
is  available on some issues.  Center personnel then use
these  reviews  in the assessment of the problems and
in  the  development of  pollutant  characterization
documents.  These documents form a major compo-
nent of the data base used by the Agency  in.making
decisions on control and in deciding upon  actions to
be initiated.
   The  Center  also provides assistance to the NATO
Committee  on  the Challenge of Modern Society
(CCMS), the Organization for Economic Cooperation
and  Development  (OECD),  and  the World  Health
Organization (WHO) in developing air quality guide-
line documents as well  as updating annually the infor-
mation on primary ambient  air quality criteria and
hazardous pollutants.
 14
                                                                             ANNUAL  REPORT  1973

-------
LEGISLATIVE
 MANDATES

-------
fffiiJSit-  A\v
i1'        s&v

-------
LEGISLATIVE
   MANDATES
   ACTIVITIES OF THE NERC-RTP ARE EITHER
in response to explicit mandates given in legislative
acts  or derived  from  language that requires the
initiation of certain programs to carry out the intent
of those mandates.
   Illustrated  in Tables 1  and 2 below  are the re-
sources of manpower  (i.e., man-years and funds) that
the several Laboratories of the Center have been
allocated  to  carry out particular  portions of the
relevant Acts.  Tables 1  and 2 are followed by a brief
narrative description of each Section of the Clean Air
Act and the  specific responses  of the appropriate
Center units.
                                                                          Clean Air Act
                                                      Activities of NERC-RTP units are responsive to at
                                                   least 1 3 Sections of the Clean Air Act: 103, 1 04, 1 08
                                                   through  113, 202, 211, 303,  312, and 313.  The fol-
                                                   lowing portion of this section of this Report outlines
                                                   each of the Sections and relates them to the activities
                                                   of NERC-RTP laboratories.
Research activities conducted at NERC-R TP are based
on explicit environmental mandates of the Congress
of the United States.

Legislative Mandates
SECTION 103:  "RESEARCH,
INVESTIGATION, TRAINING,
AND OTHER ACTIVITIES"

   The essential feature of Section 103 is the require-
ment for  EPA to establish a national research and de-
velopment program for the prevention and control of
air pollution.  In addition to the conduct of in-house
research  studies, surveys,  etc., the requirements  in-
clude  provision  of assistance to other public and
private agencies  and institutions to conduct experi-
ments, studies, demonstrations, and training activities,
as  well as technical  services relating to the causes,
effects, extent, and control of air pollution. To help
meet these requirements, the Act authorizes EPA to
establish technical  advisory committees; to cooperate
with and utilize the resources of other Federal, public,
and private facilities; to make  research grants and
contracts;  and to develop practical processes and
methods  for  air  pollution control.   EPA  is  to
emphasize short- and long-term effects  of air pollut-
ants on health and welfare by epidemiological, clinical,
and laboratory studies.
   Table  1  indicates that the  largest  category  of
activities  at NERC-RTP is that which involves carry-
ing out the mandates imposed by this Section of the
Clean  Air Act.  All but one of the laboratories are in-
volved to some  degree; over 90 percent of the  re-
sources of the Human Studies Laboratory (HSL) and
the Meteorology Laboratory (ML) are so committed.
                                           17

-------
        Table 1. SUMMARY OF RESOURCES EXPENDED BY NERC-RTP TO MEET LEGISLATIVE
                      MANDATES OF CLEAN AIR ACT FOR FISCAL YEAR 1974
                                           ($103/man-years)

S 6ction
of Act
103
104
108
109
110
111
112
113
202
211
303
312
313
Total
Laboratory3

OD













SSS
156/3

158/3






718/12


10/1
HSL
8461/104












EBL
1896/20












CPL
536/5

1587/23
562/9
2393/13
1847/17
330/5

636/13
780/5


59/2
QAEML
833/28

90/3

1182/14
405/10
274/8
103/3

225/1


112/6
ML
5940/49



275/12





36/0

50/0
CSL
4030/24
3546/21
1934/11

1934/11
3675/22
967/6




32/0

637/14


Total
21,852/233
3,546/21
3,769/40
562/9
5,784/50
5,927/49
1,571/19
103/3
636/13
1,723/18
36/0
32/0
231/9
46,409/478
aOffice of Director (OD), Special  Studies  Staff  (SSS),  Human Studies Laboratory (HSL),  Experimental Biology
 Laboratory (EBL),  Chemistry  and  Physics  Laboratory  (CPL),  Quality  Assurance and Environmental Monitoring
 Laboratory (QAEML),  Meteorology Laboratory (ML), Control Systems Laboratory (CSL).
        Table 2. SUMMARY OF RESOURCES EXPENDED BY NERC-RTP TO MEET LEGISLATIVE
                              MANDATES OF PHSA, FIFRA, AND FDCAa
                                           ($103/man-years)


Act
PHSA
(Section
241)
FIFRA
and
FDCA

Office of
Director
78/2


125/3


Human
Studies
Laboratory
299/9





Experimental
Biology
Laboratory
1 1 80/47





Pesticides and
Toxic Substances
Effects Laboratory



3141/91




Total
1557/58


3266/94


 Public  Health Service Act  (PHSA); Federal
 Cosmetic Act (FDCA).
Insecticide,  Fungicide, and  Rodenticide Act (FIFRA); Federal Food, Drug, and
   The Special Studies Staff (SSS)  is concerned with
the  preparation,  assessment,  and  dissemination  of
scientific and  technical documents  and  publications
related to air pollution research and control activities
impinging upon the total  research  and development
program, as  well as on specific aspects commensurate
with several provisions of  this Section  of the Act.
                    The effort of the Chemistry and Physics Labora-
                 tory (CPL) in this area deals primarily  with  studies
                 relating  to analytical methodology and  atmospheric
                 chemistry research.
                    The Control Systems  Laboratory (CSL)  conducts
                 research  to  characterize  emissions  of  pollutants,
                 evaluate  control technology, predict  future needs,
18
                                      ANNUAL  REPORT  1973

-------
 and develop and demonstrate the most promising and
 cost-effective control methods for stationary sources.
   The  Experimental  Biology Laboratory  (EBL) in-
 vestigates  the  effects of  gaseous  and  particulate
 pollutants  on  biological  species,- i.e.,  whole  animal,
 organ, cellular,  and sub-cellular components. Particu-
 lar emphasis is  given to effects on pulmonary defense
 mechanisms and pulmonary carcinogenesis and on the
 influence of  interactions between coexisting  pollut-
 ants and various physical factors upon these responses.
   The  development and  conduct of studies designed
 to define relationships between  environmental  pol-
 lutants  (singly  or  in  combination) and specific un-
 desirable health effects is the prime objective of HSL
 activities.  Emphasis is given to  the development of
 bases for ambient air and emission standards com-
 patible  with  desirable aspirations for  human  health
 and welfare, and an evaluation of the health benefits
 that could be achieved.  The assessment of  adverse
 health effects  and the economic  costs  that might re-
 sult from any future revision of air quality standards
 is also a part of the HSL program.
   The  activities of ML focus upon research relating
 to the  transport and dispersion of  air  pollutants,
 their  effects on weather,  visibility, and climate; and
 the relationship between  weather factors and pollu-
 tion.    Dispersion  model  development and climatic
 analysis investigations improve understanding  of the
 physical processes involved  in (1) the relationships
 between source strength and receptor dosage, (2) the
 ultimate disposition (fate) of pollutants in the atmos-
 phere, and (3) the delineation of a national climatol-
 ogy of the potential for adverse  accumulations of air
 pollutants.
   QAEML  engages in the  evaluation, testing,  and
 standardization of methodologies for  surveying the
 extent of air pollution as  well as  in the development
 of quality control procedures to ensure comparability
 of data wherever collected in the United States and
 for whatever purpose.
SECTION  104:  "RESEARCH
RELATING TO  FUELS
AND VEHICLES"
   Section  104 charges EPA with the responsibility
for conducting  and supporting research  into the de-
velopment, laboratory  and pilot testing,  and demon-
stration of  improved  methods for the prevention and
control  of  air pollution from  combustion of fuels.
   Activities by CSL under this mandate include the
development  of techniques  for the  reduction  of
nitrogen oxide emissions from combustion processes
and  the  demonstration  of  commercially feasible
means for the reduction of significant pollutants from
coke oven emissions.  Possibilities for effective, low-
cost processes for cleaning  coal are  of  current con-
cern.
SECTION  108: "AIR QUALITY
CRITERIA AND CONTROL

TECHNIQUES"

   EPA is required by Section 108 to ascertain those
pollutants judged  to have an adverse effect on public
health and welfare and  maintain  an up-to-date list
that  it publishes  from  time  to time.  Air quality
criteria for these pollutants must then be issued pre-
senting the latest scientific knowledge  on  the  kind
and extent of identifiable effects that  may  be ex-
pected from varying concentrations of the pollutants
in ambient air. Along with  these criteria,  informa-
tion on air pollution control techniques or methods
must be issued, including data on alternate fuels and
processes that will result in elimination or significant
reduction of the pollutant emissions.
   Preparation  of  the criteria  and scientific summary
documents that serve as the  legally  defensible basis
for the  development of control  stategies  and  the
promulgation  of ambient air quality standards  is the
responsibility of the Special Studies Staff.
   A major program  in  CPL  is  the  development  of
analytical  methods and  instruments to  be used  in
health and welfare studies to  aid in the evaluation or
revision  of air  quality criteria.   Also,  considerable
effort is going  into the development  of measurement
technology for pollutants that  may be considered
candidates for  air  quality criteria, e.g., fine  particles.
   In support of this Section, CSL is evaluating new
and existing  stationary  source  control  technology
procedures on a continuing basis.
   QAEML maintains  the capability  to  evaluate
methodologies   and  undertake  surveys to  obtain
scientific  information  needed by the developers of the
criteria documents.
SECTION 109: "NATIONAL
AMBIENT AIR QUALITY
STANDARDS"

   For each  pollutant  for  which  an  air  quality
criteria document has been issued, Section 1 09 of the
Act  requires  that  national primary and secondary
ambient air quality standards be set. Primary stand-
ards concern the  minimum level  of air quality neces-
sary  to prevent  adverse  health  effects; secondary
standards  are aimed  at the prevention  of adverse
Legislative Mandates
                                             19

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effects on "welfare"; e.g., plants, animals, materials,
and climate.
   Considerable effort in support of the standards is
being  made in CPL, particularly to further define the
atmospheric relationships involving hydrocarbons and
oxidants.  Development of continuous measurement
instrumentation  for nitrogen  dioxide (one of  the
pollutants for which standards have been set) and the
evaluation of the reference method  for measurement
have been accomplished.


SECTION 110:
"IMPLEMENTATION PLANS"
   In  accordance  with  a  prescribed  time schedule,
Section 110 requires each state  to prepare and submit
to EPA a plan that provides for the implementation,
maintenance,  and enforcement of  the primary and
secondary ambient air standards promulgated in ac-
cordance with Section  109. In turn, EPA must make
a thorough examination and evaluation of the plan's
adequacy in technical concept and allocated resources.
If a state fails to submit such a plan  within  the pre-
scribed time, or if the plan is judged to be not in ac-
cordance with the requirements of this Section,  then
EPA must prescribe  (or revise)  a plan that meets the
requirements.  Section  110 also includes the steps
and procedures for notices, hearings, or court actions
that must or may  be utilized in arriving at the objec-
tives sought.
   CPL is involved here to support development of
chemical and physical air pollution models for reactive
pollutants for use  in implementation plans, including
site criteria for large area sources.
   CLS's role is  primarily  in providing expert testi-
mony relating to the availability of air pollution con-
trol technology that could be incorporated in the
implementation  plans  as  they relate to the abate-
ment  of pollutants from specific sources.
   ML provides direct assistance in  the evaluation of
the meteorological  (i.e.,  transport  and  dispersion)
portions of implementation plans.
   QAEML activities support  this Section  by  the
evaluation and standardization of methods  of measure-
ment  for the  pollutants  for  which  standards  have
been  set, and by  the development and dissemination
of quality control  procedures  for  the standardized
methods.


SECTION 111:  "STANDARDS OF
PERFORMANCE  FOR

NEW STATIONARY  SOURCES"
   The emission of  pollutants  from  new stationary
sources must  be regulated under Section 111 of the
Act.  Categories of such sources are to be established,
and uniform  national  standards that would require
application of the best available control  technology,
considering the cost, for air pollution prevention must
be set.  EPA must also determine the procedure that
the states are to follow in setting emission standards
for existing stationary sources.
   Extensive support is provided by CPL in verifying
and improving the  reference  methods  of  emission
measurements and in developing performance criteria
for the  determination of compliance with the new
source performance standards.
   CSL  evaluates  the state-of-the-art air pollution
control  technology  for various stationary  sources
and, based on projected future control needs, de-
velops new control technology.
   QAEML provides  support here in a manner analo-
gous to  that for Section  110, again by the evaluation
and standardization of measurement methods and by
the development and dissemination  of quality control
procedures for the standardized methods.


SECTION 112:  "NATIONAL

EMISSION  STANDARDS FOR

HAZARDOUS AIR POLLUTANTS"
   Section 112 gives  EPA the authority to set nation
emission standards for hazardous air pollutants, de-
fined as  materials discharged into the atmosphere that
have a proven relationship with increased mortality
rates, or with incapacitating or serious illness.
   CPL  is responsible  for developing the  analytical
methodology  for the national emission standards for
hazardous materials.  Improved sampling  and analysis
methods are under development for a number of sub-
stances  including asbestos, mercury, and polycyclic
organic matter.
   The  identification  of all  air pollutants from sta-
tionary  sources is  included in  the programs of CSL.
As the need for control  is indicated, the best tech-
nological  possibilities  and the  most cost-effective
approaches are sought  through  related research pro-
grams.
   Again, QAEML support is in terms of measurement
methods standardization  and  quality control pro-
cedures.   Technical assistance to other EPA units is
also rendered to obtain  data to assist in the determina-
tion  of  what constitutes  a  hazardous  pollutant.


SECTION 113:  "FEDERAL
ENFORCEMENT"
   The legal actions that EPA must take  in the event
that violations of an  implementation plan  are en-
countered are contained in Section 11 3. This Section
also cites penalties to be assessed for non-compliance
with the Administrator's orders.
 20
                                                                       ANNUAL REPORT 1973

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   QAEML maintains a limited rapid-response capa-
bility  to ass'st in the collection of data for purposes
of Federal  enforcement.


SECTION 202: "ESTABLISHMENT

OF STANDARDS"
   In accordance with the provisions of Section 202,
EPA must  establish  standards  of emission for any
pollutant from  new motor vehicles that is likely to
endanger public  health or welfare.  Section 202 also
delineates  a time schedule for achieving a  large (90
percent) reduction in carbon monoxide and  hydro-
carbons; additionally, the  Section outlines a certifica-
tion plan for ensuring compliance with the standards
by the manufacturers.
   CPL provides support in development of emission
protocols for fuel additive effects and in characteriza-
tion of emissions from vehicles  either equipped with
control devices or utilizing alternate  power systems.


SECTION 211: "REGULATION
OF FUELS"
   Section  211 stipulates that no fuel or fuel additive
may be offered  for sale until  the manufacturer has
notified EPA of the  product's chemical composition
and EPA registers the product.  If the fuel or additive
endangers  public health or interferes with the per-
formance of anti-pollution devices,  its use  may be
restricted or banned.  EPA may require tests by the
manufacturer to determine such  effects.
   The fuel and fuel additive registration program is
one of  the areas of responsibility  of  the Special
Studies Staff.  This program involves  information re-
trieval  activities in addition to the  conduct of re-
search programs to develop protocols that will allow
the valid assessment of the effect of fuel components
on emission products.
   CPL develops emission protocols for fuel additive
effects and characterizes the emissions from vehicles
equipped with control devices and advanced alternate
power systems.
   The support of this Section  by QAEML is in the
development and evaluation of methods of analysis
and in the collection and analysis of fuel samples.


SECTION 303: "EMERGENCY

POWERS"
   Section  303  provides EPA with the authority to
act  immediately to restrain the emission of pollutants
presenting  an imminent and substantial danger to the
health of  persons when  appropriate state or local
authorities   have not acted to  abate such sources.
   ML provides direct meteorological  support for the
assessment of weather  factors and consequences  in
actual  or  potential  emergency  or  accidential  air
pollution episodes.


SECTION 312:
"COMPREHENSIVE ECONOMIC

COST STUDIES"
   Included in Section  312 is the requirement for
EPA to make a comprehensive study of the economic
impact of air quality  standards as well as an analysis
of the national requirements for, and the cost of, con-
trolling emissions to attain those standards.
   In this connection, CSL undertakes research  and
demonstration projects leading to the development of
comprehensive data relating to the cost of various air
pollution control techniques.


SECTION 313: "ADDITIONAL
REPORTS TO  CONGRESS"
   The Administrator is required  to  submit annual
reports  to Congress  giving the  progress made in
implementing the purpose and intent of the Clean Air
Act (and amendments).  Included must be statements
of the (1) status of enforcement actions, (2) progress
on control  techniques, and  (3) standards set or under
consideration.
   The Special Studies Staff has a major responsibility
in the preparation of such reports to Congress and in
the identification of problems and additional research
efforts  that should be  brought to the attention of
that body.
   CPL  provides  input  to the progress reports to
Congress on air quality and emission instrumentation
and  on emission  standards for  moving vehicles.
   ML  contributes to these reports  by interpreting
the effects  of weather and climatic factors on existing
or proposed air pollution control strategies to ensure
that the effects of abatement actions can be isolated
from natural variations.
   Air quality and emissions data, as well as measure-
ment  methods developments, by  QAEML are often
included in the reports to Congress.
  Public Health Service Act

SECTION 241:  "RESEARCH  AND
INVESTIGATIONS"
   Section 241  of the  Public Health  Service  Act
authorizes research, investigations, experiments, dem-
onstrations,   and studies  relating  to  the causes,
diagnosis, treatment,  control, and  prevention  of
Legislative Mandates
                                           21

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physical and mental diseases and impairments of man.
Under this broad charge,  EPA has the responsibility
to provide Federal guidance on  both ionizing  and
non-ionizing  radiation  problems  affecting  health.
This  responsibility includes the authority to establish
environmental standards for  safe levels of radioactive
materials.
   The Experimental Biology Laboratory conducts an
extensive program on the known and potential health
effects of  electromagnetic non-ionizing radiation and
ionizing radiation;  studies involving  the  latter are
centered about the  potential health effects of tritium
and  krypton-85,  both  of  which  are major  potential
effluents from nuclear fuel reprocessing plants.
   Epidemiologic studies on  the effects of exposures
from radioactive materials  in Japan  are under the
jurisdiction of HSL.
                  FDCAandFIFRA
   Provisionsof the Federal Food, Drug, and Cosmetic
Act  and  the  Federal  Insecticide,  Fungicide,  and
Rodenticide Act,  taken together, seek to  protect the
safety of the nation's food supply by preventing con-
tamination  that  might  arise through  the  use of
chemical controls to protect crops and livestock from
pests  and  diseases.   These  provisions require the
registration (with EPA) of all such "poisons" as well
as the filing  of all  test  results and claims made for
them.  Also  required by these  Acts is the establish-
ment of tolerances for pesticides in or on both human
andanimal food;this responsibility has been delegated
to EPA.  This provision means that "registration for
use" of a pesticide that  would leave  a  residue  on a
food or feed crop is granted only when  a tolerance
established by  EPA  has  been  satisfied.   Interstate
shipment  of  non-registered  products is  prohibited.
   The entire resources of the  Pesticides  and Toxic
Substances Effects  Laboratory  (PTSEL) are devoted
to support of the responsibilities  delegated to  EPA
to carry out provisions of these Acts.  The resources
are devoted primarily to research activities to support
registration decisions and to determine and analyze
levels  of pesticide residues in or on agricultural prod-
ucts.  In particular,  data from  acute, subacute, and
chronic  studies of  laboratory animals and  exposed
human subjects are  used to augment basic  knowledge
for continued registration of toxic substances for use
in the United States.
22
                                                                           ANNUAL REPORT 1973

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  SPECIAL
FEATURES

-------

-------
      SPECIAL
 FEATURES
   EACH YEAR MANY NERC-RTP PERSONNEL
and programs reflect, in  varying degrees,  significant
areas of effort relating to EPA's overall goal of re-
claiming the  purity of this  Nation's environment.
This portion of the  Report focuses on three programs
that are of significance because of their near-universal
impact:   the  reduction  of  automotive   emissions
through the use of  oxidation catalysts; the interface
between energy and the environment, spotlighted by
the recent fuel shortage; and the efforts to abate ef-
fects of pesticides on human health and the environ-
ment.
                                                         Automotive Oxidation
                                                                                 Catalysts
Emission characterization and emission measurement
methodology work is performed at the Chemistry and
Physics Laboratory's mobile source facility.  Such
work is integral to  the  catalyst program and other
automotive pollutant research efforts.
   The 1970 Clean Air Act Amendments require that
by 1976 the emissions of carbon monoxide, unburned
hydrocarbons, and oxides of nitrogen be reduced to
10 percent  of the rate of emissions from 1970 and
1971  model year cars.  EPA published  new motor
vehicle emission standards for these regulated pollut-
ants based upon the  legislative mandate contained in
Section  202 of these  Amendments.  Although  the
regulations  require the achievement of specific emis-
sion levels for  these  pollutants,  they  do  not require
the automotive  industry  to employ specific  technol-
ogy to do so. The industry has chosen the oxidation
catalyst to  achieve  the  standards  for 1975 model
year vehicles.
   NERC-RTP has conducted its Fuel  and Fuel Addi-
tive Registration  program since  FY 1971. This pro-
gram has been specifically directed toward provisions
of Clean Air Act Section 211, providing  for  the
registration  and prohibition or control of fuels, fuel
components, or fuel  additives that are shown to have
adverse effects on automotive emissions, performance
of emissions control  devices, or public health or wel-
fare.   The major focus of both this program and  the
Mobile Source Emissions  Measurement program (con-
ducted  by   NERC-RTP's  Chemistry  and  Physics
Laboratory) has been to identify not only the effects
of fuels,  fuel additives,  and control  devices on  the
emissions of regulated automotive pollutants (carbon
monoxide,  hydrocarbons, and oxides of nitrogen),
but the effect on non-regulated emission  products
such  as particulates,  trace metals, sulfur compounds,
polynuclear  aromatic   hydrocarbons,  aldehydes,
phenols,  and the  many  other  organic  compounds
present in automotive exhaust gases.
   Early in  1973 it was  noted that, when oxidation
catalysts  were  used,  a substantial  increase  in total
particulate  emissions  resulted  when compared to
similar vehicles  using  the required non-leaded fuel
Special Features
                                            25

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but without the oxidation catalyst present to reduce
regulated emission levels.  It was determined that this
increased  particulate  emission product  consisted of
sulfuric acid aerosols.  Center research activities were
quickly shifted in both the in-house and contract pro-
grams  to investigate this "new" emission product re-
sulting from  the application of the unique emission
control device—the oxidation catalyst.
   The investigations  sought  answers to the following
key questions:

   •  Are sulfuric acid aerosol emissions unique to
      catalyst-equipped vehicles?
   •  What other unique products, if any, are emitted
      from oxidation  catalysts?
   •   How  much sulfuric acid  aerosol  is emitted?
   •  What amount of sulfuric acid aerosol would the
       general public and the driving public be exposed
       to as a result of such emissions?
   •   Would these incremental sulfuric acid exposures
       be  sufficient to  pose  a public  health  threat?
   •   How can sulfuric acid emissions be controlled?

    It  was determined that sulfuric acid, aerosols  are
 indeed  emitted  from  oxidation-catalyst-equipped
 vehicles and  that current, non-catalyst-equipped vehi-
 cles emit little, if any,  sulfuric acid.   Preliminary
 studies  indicated that low  levels of  platinum and
 alumina, the active ingredient of the catalyst and its
 support material, respectively, may also be emitted
 from such catalysts.  It was judged that approximately
 0.05 gram of sulfuric acid is emitted per vehicle mile
 from  catalyst-equipped vehicles.  These data were
 generally confirmed   by  preliminary  reports  from
 automotive and  petroleum industry research studies
 that were examining the problem also.
    NERC-RTP's  Meteorology  Laboratory conducted
 studies to provide estimates  of exposure levels to sul-
 furic acid on and near major highways.  These esti-
 mates, based on the assumed emission factor for sul-
 furic  acid  of  0.05  gram  per mile,  were  used  to
 calculate acid concentrations that would result under
 various meteorological  conditions a.nd  under various
 assumptions as to the number of motor vehicle model
 years equipped with such catalysts.
    Using the estimated  incremental  exposures cal-
 culated  by the  Meteorology Laboratory, the Human
 Studies  Laboratory provided information based upon
 its extensive epidemiological  studies  in  the  CHESS
 program  as  to the  potential public  health  risk of
 various exposure levels to sulfuric acid and particulate
 sulfates.  It  was reported that the localized levels of
 sulfuric  acid aerosols emitted from catalyst-equipped
 vehicles,  after  two  model years  were so equipped,
 would exceed the threshold  adverse health effects
 levels  on several days per year on or near the country's
 major expressways.
   It  was determined,  by  both EPA  and industry
studies, that the emission levels  of sulfuric acid from
oxidation-catalyst-equipped  vehicles increase with in-
creasing  amounts of sulfur in  the  gasoline.    One
obvious control option, then, would be desulfurization
of gasoline.   The  Control Systems Laboratory insti-
tuted a contract late in 1973 to examine the technical
feasibility, cost, and impact of  gasoline  desulfuriza-
tion.   Preliminary findings  indicate  that  desulfuriza-
tion of gasoline  is technically  feasible.  The  oil re-
fineries, however, would require  4 to 6 years to install
the necessary equipment.  It is estimated that the
total cost to  the  refining industry would  be between
$2  and 3 billion depending on  the level of sulfur re-
duction required and on the number and sizes of the
refineries  involved.  The estimated cost  to the  con-
sumer would  be between  1 and 2 cents per gallon.
   The  problem relative to the  emission of catalyst
materials  themselves was  far  more  complex.   Al-
though the emission levels of platinum and  palladium
(the catalyst  active ingredients)  were extremely  low,
it  was  quickly  determined  that  these  metals are
essentially not present in the  public environment to-
day.  Thus, the use of catalysts might result  in the
introduction of "new" pollutants into the ecosystem.
An  extensive search  of the available literature by the
Experimental  Biology  Laboratory and  the Human
Studies Laboratory  indicated  that  extremely  little
work  has been  reported on  the  toxicology and/or
human effects from exposure to these metals.  The
information available  is  based  upon  industrial ex-
posures in the few processing plants that  exist, and
these  studies suggest that noble metals probably are
allergens.  Adverse allergenic reactions were reported
at very low exposure levels.  I n addition, a  preliminary
study suggested that these  metals may methylate  in
the water ecosystem in much  the  same fashion  as
mercury.
   These findings  indicated a need for substantially
more  information  on the potential of noble metals to
adversely affect public health.  Accordingly, extensive
toxicological,  biological, and physcological  studies
were funded  both in-house and under contract by the
Human Studies  Laboratory and the  Experimental
Biology Laboratory in Fiscal Year 1974.
   The  concerns voiced by  NERC-RTP regarding the
potential  adverse  effects associated with the use  of
oxidation catalysts resulted in am extensive Agency re-
view  of the  problem  and,  finally,  in  hearings  con-
ducted  by the Senate  Public Works Committee on
November 5 and 6, 1973.
   The issues involved were  indeed complex. The use
of oxidation  catalysts offered,  on one hand, a  very
definite benefit to public health through the  reduction
of  carbon  monoxide,   hydrocarbons,  and organic
emissions.   Yet,  to what  extent was  the benefit
  26
                                                                             ANNUAL REPORT 1973

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threatened by the potential adverse effect associated
with exposure of the public to sulfuric acid emissions
and/or noble metals?

   Participate  sulfate  compounds, of which sulfuric
acid is one, are currently present in ambient air.  In
fact,  many  urban areas  have  levels  that exceed the
health effects threshold  now  on many days of the
year.   Sulfur in gasoline  is emitted from our current
vehicle population as  sulfur dioxide, which disperses
and reacts in the atmosphere  to form sulfates. The
automotive-generated sulfur dioxide amounts to about
1 percent of the man-made sulfur dioxide emissions
on a  national  basis.  The automotive catalyst,  there-
fore,  causes an  immediate conversion of some of this
gas to sulfate, resulting in increased concentrations on
and near  areas of high vehicle density.   The public
health problem, then,  is  one of adding  an increased
localized concentration of sulfate to existing  ambient
sulfate concentrations.

   In  testimony before the Senate in November 1973,
the  Administrator of EPA voiced  his decision regard-
ing the catalyst issue:
   •  EPA  will permit the  use of catalysts on 1975
      model year vehicles.

   •  EPA  will conduct an  expanded and accelerated
      research and  monitoring program to ascertain
      the   validity  of  projected health  and early
      emissions data.

   •  EPA  will conduct an appropriate  program to
      consider control options if the predictions are
      borne out.

   The  initial  part of the  expanded monitoring pro-
gram was begun in the spring of 1974 by NERC-RTP's
Quality  Assurance  and Environmental  Monitoring
Laboratory.   This  program  is  directed  toward  the
gathering of base-line information at selected highway
sites in  Southern California concerning  the amount,
types, and  concentration profiles of sulfur emissions
from the current vehicle  population.  The research
and  monitoring program will  greatly expand in Fiscal
Year 1975 and will include most NERC-RTP  labora-
tories in a  program directed by the Special Studies
Staff within the Fuel  and  Fuel Additive Registration
program.

   The  objective  of  this  program  is to  gather  the
necessary  information  to  ensure   that  the  use  of
oxidation catalysts  on  future passenger  vehicles  re-
sults in  a net benefit to public  health.   The results
from this  program  are  distributed  to  and used  by
other Agency offices,  the Administrator and his staff,
and the  Congress of the United States.
                    Energy and the
                        Environment
THE PROBLEM
   The  fundamental  energy  problem  facing  the
United  States is  the growing gap between  energy
consumption  and domestic  energy  production.   In
1950, the United States was self  sufficient in  energy
production; in 1973, 76 X  1015  Btu of  energy was
consumed,  of which 62 X  1015  Btu was produced
domestically.   (The use of imported oil represented
the major difference between production and con-
sumption.)   Today  15  percent of our total  energy
needs, and 35 percent of our oil, is imported.   Energy
consumption  in the United States is increasing at an
annual rate of almost 4.5 percent; whereas, the rate of
domestic energy production has  been at  a standstill
since 1970.
   The  oil embargo directed by  Middle Eastern  oil-
producing countries forced recognition of the serious-
ness  of  the energy gap before American dependence
on imported oil presented an unmanageable problem.
There is still time, therefore, to evolve  a  national
energy program of conservation and development that
will  make  us independent  of foreign supply.   Al-
though  environmental  regulations  may have  made
the energy  problem more severe or precipitated it
somewhat earlier, the basic  problem  is that the U.S.
cannot sustain the rate of increase in energy consump-
tion experienced during the last few years.
   Energy production and use and the environment
are inextricably intertwined:  the major source of air
pollution is fuel combustion either in furnaces or in
internal  combustion engines.  Thus, the control of
emissions  both from these sources and from  the
related extraction, processing, and handling of  fuels is
the major means of controlling air pollution.
   Pollution costs are difficult to measure in monetary
terms. EPA estimated that air pollution damage in  the
U.S.  in 1968 amounted to:

     $6.1 billion for damage to human health.
     $5.2 billion for residential property damage.
     $4.7 billion for damage to inert materials.
     $0.1 billion for vegetation damage.

   Pollution  control activities since  1968  have  re-
sulted in a  reduction in pollution damage, however.
   Another potential long-range problem is the possi-
bility of changes in climate as carbon dioxide and fine
particulates build  up in the  air.  Some scientists be-
lieve  this  problem  already  exists  to some  degree.
Dr.  Reid  Bryson,  director of  the  University of
Special  Features
                                               27

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Wisconsin's Institute of Environmental Studies, states:
"Up to  50 years ago man's influence on the climate
was negligible. Then it started to increase.  Over the
past century  it has  worked out to 16 to  20 percent
compared with natural influences.  But this means it
has been very high in recent years, because it was so
low earlier.  Today  it is quite comparable to natural
causes."
   A  key to  solving  the  energy  problem may  be
found by analyzing the nature of energy consumption.
Approximately 50 percent of the energy produced in
the United States is wasted. This makes a  strong case
for conservation  as the prime  element  in energy
management. Because air pollution is directly propor-
tional to  the  amount and  type  of fuel  consumed,
energy  conservation also  promotes  environmental
goals.    For  example,  solar  energy  is  "free" and
environmentally clean; heat pumps are both efficient
and  non-polluting (especially  from  an area source
standpoint).  Although  add-on pollution  control  de-
vices usually  increase energy consumption by 5 to 10
percent,  on balance there is more commonality than
disparity in energy and environmental goals.
   Table  3 shows that substantial energy savings can
be realized in industrial, commercial, residential, and
transportation applications if new technologies are
employed. The achievement of energy self sufficiency
will  not  be  easy, but  zero energy growth  can be
reached  while  still enjoying the "good life."   If
Americans discipline themselves to some changes  in
their  way  of life,  and demand  a  sound  national
energy policy, the problems can be solved.


ERA'S ROLE

   EPA's  research  and development  role  in the
national  energy/environmental  program is  not  com-
pletely defined,  nor will  it be until  the  proposed
Energy Research and Development Agency structure
is clearly established by  the Congress.  It is generally
agreed,  however,  that  effects  research (health and
welfare)  and  the assessment of the pollution charac-
teristics of the various energy extraction, transporta-
tion, preparation, and transformation technologies are
part of EPA's charter.
              Table 3.  POSSIBLE ENERGY SAVINGS THROUGH USE OF CONSERVATION
                            TECHNOLOGY AVAILABLE IN 1985 AND 2000a



Sector
Residential-
commercial





Transportation





Industrial






Total

% of
total
demand
35






25





40






100
1985


Method
Heat pumps, total energy
system, solar heating
and cooling systems, better
insulation, tighter building
construction, more effici-
ent furnaces and air condi-
tioners
Cars with fuel economy of
25 mi/gal, improved air-
craft load factor and ,
efficiency, short-haul air
freight shifted to rail.
truck freight shifted to rail
Improved maintenance (e.g.
steam leaks fixed), energy-
using systems turned off
when not needed, heat
loss eliminated from
buildings, more efficient
electric/steam systems



Savings,
%
6






20





25






17
2000


Method
Catalytic combustion
processes, advanced
fuel conversion
systems, advanced
total energy systems

i
Electric vehicles
(fuel cell and battery).
improved mass transit
systems


Full use of total
energy systems (com-
bined steam/electric),
heat pumps, solar
heading and cooling
systems




Savings,
%
45






50





50






48
          istorical growth:  1972-100 percent, 1985-160 percent, 2000-255 percent.
 aBased on hi
 28
                      ANNUAL REPORT 1973

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   There  is some question  whether EPA will  retain
its capability to develop pollution control technology
for energy processes—a capability that is the key to
environmental  protection.   Energy  developers  will
probably  be interested mainly in  developing the most
efficient energy processes with concerns for adequate
environmental  control  technology  of  secondary  im-
portance.  EPA must have the  authority to develop a
better pollution control  system  in  those cases in
which the pollution  control measures taken  by  the
energy developer are considered  inadequate by EPA.
   The  problem of energy and the environment be-
comes even more acute when  it is realized that the
main  energy  utilization systems for the  forseeable
future are to be developed within the next 5 years by
a massive, government-financed research and develop-
ment program.  Within this  brief period of time,  it
will be impossible to quantify  adequately the pollut-
ants of concern and  to assess their associated health
effects. It will thus be impossible to accurately define
the pollutant  control levels required.   Furthermore,
once  the  energy technologies are in  place it  will be
difficult   and  expensive to   retrofit them  with  im-
proved  pollution  control equipment:   retrofit may
cost three times as  much as that  of  installation of
original equipment.  The best means of protecting
the public's health  is to have an active pollution con-
trol  program to  develop  new  and  improved control
methods  for these energy systems that  will provide
the minimum  pollution levels that can be achieved
technically at an acceptable cost.
PRESENT AND  FUTURE
PROGRAMS AT NERC-RTP

   Of  primary concern to EPA is the  protection of
the health and welfare of people.  Therefore, a major
portion of NERC-RTP's program  is directed toward
minimizing the effects of  air pollution on health.  Two
broad  areas  of  research  are  being  given  special
emphasis:  studies of the human response to exposure
to specific pollutants (singly or  in combination) that
are likely to be emitted to the atmosphere in larger
quantities because of the fuels used and programs for
the development of methods for controlling emissions
from  both stationary and mobile  power generating
facilities.
   Within NERC-RTP, the Human Studies Laboratory
(HSL)  and the  Experimental  Biology Laboratory
(EBL)  have primary responsibility for studying the
health  impact of  policy  decisions  concerned  with
energy production.   These  Laboratories conduct  a
comprehensive program of lexicological, clinical, and
epidemiological  studies  to assess  the effects of air
pollutant  exposure  on human health.  The Control
Systems Laboratory (CSL) has the main responsibility
within NERC-RTP for developing technology to con-
trol air pollution.
   It  is acknowledged that the greatest increases in
human  health risks will  be associated  with increased
pollution  resulting  from  the  greater  use of coal to
fuel  power-generating facilities.  The  pollutants of
primary  concern are  sulfur oxides and trace sub-
stances  that contaminate the coal.  The sulfur oxides
are emitted as gases as the coal is burned, but  in the
atmosphere they are transformed at a  regular rate to
sulfuric acid mist and particulate sulfates.  HSL stud-
ies, therefore, attempt to develop information relative
to adverse health effects associated  with exposure to
ambient concentration of total suspended particulates.
(Fine sulfates and nitrates are particularly  suspect.)
   EBL  has initiated studies in  laboratory animals to
determine  the  relative  toxicity  of  various  metallic
sulfates.  HSL, as part of its responsibility, conducts a
continuing  program  of studies  to determine  the
adequacy   of  all  established  ambient  air  quality
standards.  During the  fiscal year, more than $1 mil-
lion was spent  for this purpose on  studies of the ef-
fects of SOX and particulate matter  on  human health.
In addition, $3.4 million was allocated to HSL from
the energy  program to study  the  health impact  of
decisions  concerning  the  alternative  strategies  for
power production. These funds were used to  support
contract studies  of the effects of  sulfates, nitrates, or
total respirable  particulates on human health.   The
funds also supported a $1 million interagency agree-
ment  with the  National Institute of Environmental
Health  Sciences to  provide  additional  information
(from a  non-EPA source) on  the effects of  energy-
related  pollutants.  These separately  collected data
sets are  expected to verify EPA  studies  and  provide
greater  overall   support  to policy  decisions  made
within  the  Agency.    One of  the  major objectives
of the  program  in  Fiscal Year  1975 will  be  the
development of more precise measurements of human
exposure  in ambient  situations  to permit  the  es-
tablishment of  relationships   with air  monitoring
data  as  well as closer coordination between the field
epidemiological  efforts  and the carefully controlled
clinical laboratory studies.  Other studies will expand
the effort to obtain  data  on human  response  to
specific  particulates both in a clinical  setting and in
ambient air situations.
   The financial  support  given to  research into  issues
raised by the energy  problem will first  of all  provide
for a more rapid development of  health effects data.
It  is  likely,  however, that the financial support will
also intensify the energy problems because additional
study is expected to show that relaxation of efforts to
reduce air pollution levels may well result in significant
increases in the  incidence of adverse health effects-
effects that can  be measured by  increased mortality
Special  Features
                                               29

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rates, increased  prevalence  of  chronic  respiratory
illness,  poorer  pulmonary  function,  and increased
aggravation of symptoms in asthmatics or individuals
with cardiac illness. The trade-off of increased health
risk to meet ever-increasing energy demands may well
be a point on which  individuals with diverse interests
will find it difficult to agree.
   For the long  term, however,  the increased effort
at this time  will provide a stronger  basis on which
decisions can be  made that  may  change our attitudes
about energy  conservation, the  degree of pollution
control required, and (to some extent) our life style.
This increased effort  will ultimately assure a healthier
environment for all of us.

   The Control Systems Laboratory program includes
several projects that  will  have a major impact upon
the availability of  clean energy.  The  projects under
development, although generally not  specifically re-
lated to the energy production process, are focused
upon the control of emissions of harmful pollutants.
Because of simularities in control requirements and
processes, methods  developed  for  the  control of
industrial  emissions  may  be  applicable  to  energy-
related processes; for example, research and develop-
ment  on scrubbers would  be  applicable  to  electric
utilities as well as to  chemical plants,  pulp and paper
plants, oil refineries, and steel mills.
   Perhaps EPA's  most significant  contribution to
clean  energy  production is  flue gas cleaning:  about
80 percent of CSL's expenditures to  date have been
concentrated  in this area. CSL's early efforts helped
develop the  limestone  scrubbing  process,  and its
present efforts are  helping to lower costs and increase
effectiveness and reliability.  CSL is  participating in
the development of  many  other advanced flue gas
cleaning prototype demonstrations including magne-
sium oxide scrubbing, catalytic oxidation, sodium ion
scrubbing with  thermal  regeneration, and  sodium
hydroxide scrubbing with electrolytic regeneration.
Clean fuels and flue  gas cleaning are  the only tech-
niques expected to  be applied to a large extent in con-
trolling  sulfur oxides emissions  during the next 10
years.   With  the  probable shortage  of clean fuels
(clean coal will amount to  about 20  percent of the
demand), flue gas cleaning will apparently have to be
applied widely.

   With respect to  energy production  processes, CSL
is currently developing technology for the control of
sulfur oxide',  fine particulate, and nitrogen oxide that
will  be  applicable to both  combustion  and  non-
combustion sources.  Projects to assess and ultimately
control  the  environmental  impact of  new energy
processes have already begun.  Finally, activities have
recently  been initiated for the characterization  of
potentially hazardous  pollutants from  combustion
and other sources.   This  program will lead to new
control technology development as additional source
and pollutant information becomes available.
   As part of the concerted  Federal effort to solve
the energy  crisis,  EPA's  Office  of  Research and
Development-with  substantial support from  NERC-
RTP's Control Systems Laboratory-participated fully
in the  Energy  Research  and Development Program
Task Force effort that produced A Report to Richard
M. Nixon, President of the United States-The Nation's
Energy  Future.   This interagency effort  and sub-
sequent evaluation,  planning, and coordination with
the Office of Management and Budget resulted in a
$186 million supplement to EPA in Fiscal Year 1975
to address the important areas of environmental assess-
ment and control technology development.
   As part of an effort to  develop and coordinate  an
EPA-managed  environmental research  and develop-
ment  program to interface with the Federal  energy
program, EPA's Office of Research and Development,
with substantial support from NERC-RTP, undertook
a matrix planning exercise to prepare specific program
objectives.   The four major energy research and de-
velopment areas covered were fossil fuel combustion
and conversion, fossil fuel extraction,  conservation,
and nuclear and advanced systems.  To define the
environmental impact of energy technologies in these
four areas,  EPA's contribution to the complex  re-
search and development matrix included environmen-
tal  information systems development,  measurement
and  monitoring  efforts,   health  efforts  research,
ecological processes and effects research, social effects
and  policy  implementation  studies,  air pollution
control,  industrial  water  control, and  non-point
source control.
   EPA's overall aim is to  provide increasingly  ac-
curate  and  comprehensive  information  to  permit
environmental impact assessment  and environmental
policy  formulation  relative  to  a specific  energy
technology.  Before actual commercial application of
energy   technology,  it  is  EPA's   aim  to have the
national environmental impact defined and the siting
criteria  developed to the  point where they  can  be
utilized  to provide a basis  for evaluating the environ-
mental  suitability  of sites  throughout the  United
States.    This  definition  will  allow comparison  of
alternate energy technologies  on  the  basis of their
overall environmental impact.


          Substitute  Pesticide

                             Chemicals

   NERC-RTP's Pesticides and Toxic Substances Ef-
fects Laboratory  (PTSEL) is  involved  in studies in
two major areas relating to substitute chemicals. The
 30
                     ANNUAL  REPORT 1973

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first area relates specifically to pesticides and pesticides
substitutes;  the other relates more generally  to toxic
substances.
PESTICIDE CHEMICALS

PROGRAM

   The  1972  Federal  Insecticide,  Fungicide,  and
Rodenticide Act (FIFRA), as amended, places an in-
creased emphasis on  EPA to regulate pesticide chemi-
cals through full consideration of the consequences on
human health and on the environment from the use
of  pest  control  products.   The  determination to
cancel or suspend a product registration is made after
exhaustive review of the pesticide and of the potential
harm of  pesticide materials  designated  as  potential
substitutes.  Recognizing the enormity of the program
to evaluate the hazard  of a pesticide and to  assess the
acceptability  of a substitute if removal is indicated, a
$5  million,  50-position program to study  pesticides
and feasible substitute  chemicals was included as part
of  the  proposed Agricultural, Environmental,  and
Consumer  Protection  Appropriation Bill for  1974.
   Three integrated strategies were considered  neces-
sary to implement this program: (1) scientific review
of known registered  pesticides, (2) establishment of a
cooperative  liaison  with industrial  research and de-
velopment to expedite  the development of  pesticides
as substitutes for those removed from use, and (3)
generation  of  data  relative to the problem  of  a
pesticides hazard asa  function of toxicity, persistence,
and  potential for  eliciting an  undesirable  response.
The  review  processes will define data gaps in back-
ground information  that can be filled by  initiating
research,  monitoring, and testing programs.
   PTSEL maintains several broad  areas of responsi-
bility, including inhalation toxicology; toxicity screen-
ing and testing; chemical determination of toxicologi-
cally  significant impurities  in  commercial prepara-
tions  of  pesticides;  and multiresidue  methods for
detection of  pesticides. Primary programs  are being
designed  to satisfy the  questions arising in the review
process of pesticides and to  allow a  rapid response to
all inquiries and thus permit the review and admini-
strative actions to be completed in a minimum of time.
It  is anticipated that this program will allow EPA to
expeditiously remove materials  from the market that
are  designated as harmful to humans or the environ-
ment, and will further allow EPA to rationally assess
materials  designated as substitute chemicals.
TOXIC SUBSTANCES EFFECTS

PROGRAM
   PTSEL  has  an expanding  role  in  assessing  the
toxicity of synthetic organic compounds, metals, and
metallic  compounds  and   in  developing  sensitive
analytical  methods for measuring toxic substances in
the  environment.    Currently, approximately  two
million  chemical  compounds  are  known;  several
thousand new compounds are synthesized annually.
Each year, several hundred of these new chemicals are
introduced into commercial  use  even though their
potential impact  on health and the environment in
most cases is not known.
   The pending Toxic Substances Control Act (TSCA)
is  an important legislative  approach to control  the
introduction  of toxic  substances into the environ-
ment.   Rather than focusing on pollutants  in  the
media (e.g., air  and water), the TSCA relies on under-
standing  the flow  of  potentially toxic  substances
throughout the  entire range of activity—from extrac-
tion (or synthesis), through production and consumer
use, to disposal.   Of  particular concern are  the
potentially deleterious effects on health resulting from
long-term exposures to  low  levels of these chemicals,
alone or in combination.
   PTSEL projects over the  past year have supported
the  research  needs  of  EPA's Office of Toxic Sub-
stances.  Animal  model studies were  completed on
the effects of polychlorinated biphenyl compounds,
hexachlorobenzene, cadmium, and TCDD  (2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin).   Preparing  for  public
hearings, PTSEL  carried out over 300  ultra-trace
(ppb) determinations of TCDD in a variety of environ-
mental samples (including human adipose tissue and
agricultural products) utilizing an improved sample-
preparation  procedure  followed   by high-resolution
mass-spectrometry analysis.
   Future  research  on  toxic substances will  include
development of rapid toxicological screening methods;
determination  of  toxic  impurities  in  commercial
chemicals; development of a tissue bank to assess the
accumulation of  toxic substances  in human tissue
over long  time periods; and the  development  of
chemical analytical methods  for  the  determination
of trace levels  of  metals, metallic  compounds, and
synthetic organic compounds.  PTSEL is also planning
to  develop  a rapid-respones capability to  address
environmental crisis situations that will involve short-
term sample collection,  chemical analysis, and toxico-
logical assessment.
Special Features
                                               31

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RESEARCH
ACTIVITIES

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VJ:

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Special
Studies
   Staff

-------

-------
 Special
Studies
      Staff
OVERVIEW OF SSS MISSION
   The Special Studies Staff,  located in the Office of
the  NERC-RTP   Director,  is engaged  in  activities
in three major technical areas:  (1) preparation of air
quality criteria documents and scientific and technical
assessment  reports  involving  pollutant characteriza-
tion,  (2)  fuel  and  fuel  additive  registration  and
vehicular  emission research, and  (3) participation in
or coordination of NERC-RTP international activities.
In addition,  the  Staff carries out various ad hoc,
short-term projects.
                    NERC-RTP
                    DIRECTOR
               SPECIAL STUDIES
                     STAFF
Scientific and Technical Assessment Reports, which
serve as  a  basis for determining pollutant control
strategies in EPA, are produced by the Special Studies
Staff.
LEGISLATIVE MANDATE

   The  legislative mandate upon  which the  Special
Studies Staff's  programs are  based  and the  various
sections of the Clean Air Act  requiring Staff support
are shown below with a brief description of the types
of activities engaged in to  support the mandate and
the Act.

   "RESEARCH,  INVESTIGATION, TRAINING,  AND
   OTHER ACTIVITIES
   "Sec. 103. (a) The Administrator shall establish a  national
      research and development program  for the prevention
      and control of air pollution ....
        "(b)  In carrying out the provisions of the preceding
      subsection the Administrator is authorized  to—
        "(1)  collect  and make available .  . .  the results of
        and other information, including appropriate recom-
        mendations by him in connection therewith, per-
        taining to such research and other  activities;.
        "(7)  collect  and disseminate .  .  . basic  data on
        chemical, physical, and  biological effects  of vary-
        ing air quality and other information pertaining to
        air  pollution and the  prevention  thereof;. .
        "(c)  In carrying out the provisions  of subsection
      (a)  of this section the  Administrator  shall  conduct
      research on, and survey  the results of other scientific
      studies on,  the harmful  effects on the health or
      welfare   of persons by   the  various  known  air
      pollutants . . .

   "AIR QUALITY  CRITERIA  AND CONTROL TECH-
   NIQUES
   "Sec. 108. (a) .    (2)  The Administrator shall  issue air
      quality criteria  for an air pollutant      Air quality
      criteria for  an  air pollutant shall accurately reflect
      the latest scientific knowledge useful  in indicating the
      kind and  extent of  all  identifiable Effects on public
      health or  welfare which may be expected from the
      presence of such pollutant in the ambient air, in vary-
      ing quantities . . .
        "(b)   (1) Simultaneously with  the  issuance of
      criteria under subsection (a), the Administrator shall. . .
      issue . . . information on air pollution control tech-
      niques . . . Such information shall include such data
      as are available on available technology and alternative
      methods of prevention and control of air pollution . . .
        "(c)  The Administrator shall from  time  to  time
      review, and, as  appropriate, modify, and  reissue any
      criteria or  information  on  control techniques issued
      pursuant to this section . . .
Research Activities
                                                 37

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   "ADDITIONAL REPORTS TO CONGRESS
   "Sec.  313      the Administrator shall  report to the
      Congress on measures taken toward implementing the
      purpose  and  intent of this Act  including,  but not
      limited to       (2) the  development  of air quality
      criteria and recommended  emission control require-
      ments ... (4) the status of State ambient air standards
      setting, including such plans for implementation and
      enforcement as have been developed. . ."

   As indicated above, Sections 103, 108, and 313 of
the  1970 Clean Air  Act Amendments permit EPA's
Administrator to require the preparation of scientifi-
cally sound assessment or criteria documents to serve
as the  legally defensible basis for both  the  develop-
ment  of control strategies and the  promulgation of
standards.  The preparation of criteria documents and
scientific and technical  assessment  reports  by this
Staff contributes to the requirement of these sections
of the Act.
   Characterization of pollutants consists of critically
reviewing,  evaluating, comparing,  and  interpreting
pertinent literature to revise present, or prepare ad-
ditional, air  quality criteria documents and  prepare
scientific and technical assessment reports that serve
as the scientific basis of control strategies and related
standards.   These  documents are  also required to
identify the need of additional research for producing
adequate criteria  for  issuing or  revising  standards.

   "REGULATION OF FUELS
   "Sec. 211.  (a) The  Administrator  may  by regulation
       designate any  fuel or fuel additive and ...  no manu-
       facturer or processor of any such fuel or additive may
       sell, offer for  sale, or introduce into commerce such
       fuel or additive unless the Administrator has registered
       such fuel or additive in accordance with subsection (b)
       of this section.
         "(b)  (1) For the purpose of registration of fuels
       and fuel additives, the Administrator  shall  require—
         "(A) the manufacturer  of any fuel to notify him
       as to the  commercial  identifying name and  manu-
       facturer of any additive  contained in such  fuels;.
         "(B) to furnish    .  such other information as is
       reasonable  and necessary to determine the  emissions
       resulting from the use of  the  fuel or additive con-
       tained in such fuel, the effect of such fuel or additive
      on the emission control performance of any vehicle or
      vehicle engine, or the extent to  which  such  emissions
      affect the public health or welfare . . .
         "(c)  (1) The  Administrator may,  from time to
      time on the  basis of information obtained under
      subsection  (b) of this section     control or prohibit
      the manufacture, introduction into commerce, offering
      for sale, or sale of any fuel or fuel additive for use in a
      motor vehicle or motor vehicle engine . . "

   Sections 211  (a)  and (b) of the  1970 Clean  Air
Act  Amendments permit the Administrator to require
the  registration  of  fuels  and  fuel additives as a
prerequisite to sale.  These  sections also permit the
Administrator to require, as a prerequisite to registra-
tion, that tests be conducted by the manufacturer to
determine the effect of such fuels or fuel additives on
38
emissions (regulated and non-regulated), the perform-
ance of emissions control  devices, public  health, and
public welfare. Such tests  are to be conducted on the
basis  of  protocols established by  the  Administrator.
   Section 211 (c) provides that any registered fuel or
fuel additive  may be restricted or prohibited based
upon  adverse  effects observed from such tests  or
from  other such information available to the Admin-
istrator.
   The Special Studies Staff's  fuel and fuel additive
program  consists  of registration and   information
retrieval activities in addition to conducting research
programs  to  develop protocols that  will allow  the
valid assessment  of the effect of fuel components and
fuel additives on emission products  (both regulated
and non-regulated), performance of emission control
devices,  atmospheric  loadings  and transformations,
and public health and welfare.
   By  contractual agreement with the World Health
Organization (WHO),  EPA was established as WHO's
International  Reference  Center  for  Air  Pollution
Control (IRCAPC).  The responsibility for responding
to  WHO   requests was  assigned  to  NERC-RTP  by
EPA's  Assistant  Administrator   for  Research  and
Development  who  is  also  the   Director of  WHO-
IRCAPC.
   The Special Studies Staff's international activities
consist of providing direct technical  assistance and
liaison  to  international  organizations in preparing
international  environmental  pollutant criteria  and
guidelines  as well as coordinating other  NERC-RTP
involvement with the WHO, Organization for  Eco-
nomic  Cooperation  and   Development  (OECD),
NATO's   Committee for  the  Concern   of   Modern
Society,  Special  Foreign  Currency Program, World
Meteorological   Organization   (WMO),   Economic
Commission for Europe, and the Council of European
Communities.
   Information  concerning  fiscal  and personnel re-
sources,  presented  in  Table 4, includes  funds and
personnel within the Agency and on contract.
Table4. SUMMARY OF RESOURCES FOR SPECIAL
    STUDIES STAFF FOR FISCAL YEAR 1974
Section of
Clean Air
Act sup-
ported
103
108
211
313
Totals


Funds,
$103
156
158
718
10
1042



Positions
3
3
12
1
19


Approximate
percent
15
15
69
1
100
                      ANNUAL REPORT  1973

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ORGANIZATION
   The  Special Studies Staff, functioning under the
genera]  guidance of a Director, concentrates on two
subject  areas—Pollutant  Characterization and  Fuel
and Fuel Additive Registration.
   To meet its responsibilities in pollutant characteri-
zation, fuel and fuel additive registration, and inter-
national activities, the Special Studies Staff emphasizes
both  extramural  tasks  with  supporting in-house
activities to obtain basic and background information,
and direction  and coordination of in-house NERC-
RTP task force activities concerning  preparation of
multidisciplinary and multimedia  environmental pol-
lutant  scientific  and technical  assessment  reports.
Pollutant Characterization
   Personnel  involved  in  Pollutant Characterization
produce  technical  documentation to  be used  in
decision-making  regarding  pollution control.   This
group assists  international organizations in preparing
similar technical documentation.  Involvement begins
with a  search  for  basic  information, and  extends
through  publication of the  document.   The Staff
Director  coordinates  NERC-RTP's  international ac-
tivities.
Fuel and Fuel Additive
Registration
   The Fuel and  Fuel Additive Registration group is
involved  in  receiving and storing  information from
manufacturers as required by law and registering their
products.  Personnel also assist in the development of
related regulations  and guide  research carried  out
external to the immediate group.
MAJOR PROGRAM AREAS

Pollutant Characterization
   The  Pollutant Characterization  activities  of the
Special Studies Staff provide documentation critically
reviewing,  evaluating,  comparing,  interpreting,  and
summarizing pertinent literature and reports.  This
documentation  leads  to the  (1) revision of existing
criteria  documents or the preparation  of additional
scientific and  technical assessment  reports for air
quality  of  currently  non-regulated  environmental
pollutants, (2) identification of the need for additional
research  required to  produce adequate  criteria for
issuing or revising standards, and (3) preparation of
briefing reports that address new areas for environ-
mental concern that are not  already part of an inte-
grated program.
   Air  quality criteria, as defined  by the  Clean  Air
Act, are compilations of the latest available scientific
information on the sources, prevalence, and manifes-
tations of recognized air pollutants. Most importantly,
these criteria  describe the  effects  that  have been
associated  with,  or may be expected  from,  an  air
pollutant level in excess  of a specific concentration
for a specific  time period.  Such effects generally
involve  visibility reduction,  damage to  materials,
economic costs, vegetation damage, nuisance aspects,
and  adverse effects on the health and well- being of
humans and animals. Air Quality Criteria serve as  the
basis  for  national  ambient air quality   standards.
   The  scientific and  technical assessment  reports
serve two very important purposes.  They summarize
the  scientific  knowledge  base for  administrative
decisions regarding the need and strategy for control;
and  they provide  important input for research and
development program  plans.  In view of their wide-
spread  distribution, these documents also serve as an
important  communications  link  with  other EPA
offices,  other  agencies, and special-interest groups.
In  order to serve  these purposes,  they must  be
functional documents,  clearly and concisely written.
   Assessment  reports are prepared under the super-
vision  of the  Special  Studies  Staff  by task  forces
made up of staff members from the laboratories of
NERC-RTP and from the other  NERCs.  The reports
are based on standard outline to ensure inclusion of
available information on the following items:

   • Chemical and physical properties.
   • Measurement  techniques  applied to  various
     environmental compartments (e.g.,  air,  water,
     and   soil),   sources,  and  (when  pertinent)
     biological samples.
   • Origin and  abundance.
   • Concentrations in air, water, soil, plants, animals
     and humans, and microorganisms.
   • Transformations and transport.
   • Environmental exposure.
   • Mechanisms of exposure.
   • Physiological response.
   • Undersirable effects on humans, animals, vegeta-
     tion,  materials, weather, visibility, climate, and
     land and water resources.
   • Control technology and remedial actions.
   • Current  research and development  activities.
     These reports are  generally  based  on  review
     material provided by panels of experts assembled
     by the National  Academy of Sciences  (NAS)
     under contract with the  Special Studies Staff,
     although  other   organizations  have  provided
     similar resources.  Supplementary information
     is used as available and  required.   When  no
     basic  review  document is available, the basic
     literature is searched.
Research Activities
                                              39

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   Basic  review  documents are being prepared  by
NAS on  vapor-phase  organic  matter, chlorine, sele-
nium, copper, zinc, arsenic, and the platinum-group
heavy  metals.   In  keeping with  timely review of
criteria  documents,  NAS  is  preparing  reviews  on
carbon monoxide, photochemical oxidants,  nitrogen
oxides, and fine  particulate matter.  NAS  recently
submitted  to  the Special  Studies  Staff  reports  on
nickel, chromium, and  vanadium.  Task forces are
currently  preparing reports on  vadium,  chromium,
nickel, and nitrates.
   Reports on particulate polynuclear organic matter,
sulfates and  sulfuric  acid  aerosols, polychlorinated
biphenyls,  cadmium,  and manganese  are now being
finalized prior to publication.
   The Special Studies Staff completed a review and
revision of the  vegetation effects chapter  of Air
Quality Criteria for Sulfur  Oxides in 1973, requiring
EPA review  of  the  secondary standards for  sulfur
oxides that  led  to  the  standards' revision.   The
Special Studies Staff has also prepared and presented
briefings  for  EPA's Office  of  Research and Develop-
ment  (ORD)  on fine particulate matter and  nitrates.
   Scientific and  technical  assessment reports are to
be prepared for selenium, chlorine/hydrochloric acid,
arsenic, vapor-phase organic matter, copper, zinc, and
platinum-group heavy metals.   A briefing document
on  particulates from mobile emissions is also to be
prepared.   The  air  quality criteria documents for
nitrogen   oxides,  photochemical  oxidants,  hydro-
carbons, sulfur oxides, particulates,  and carbon mon-
oxide are to be updated and/or revised.
Fuel and Fuel Additives
Registration
   The Fuel and Fuel Additives Registration program,
reorganized in Fiscal Year 1974  involves registration,
emissions  characterization,   toxicological  testing,
human studies, fuel surveillance and analysis,  health
and welfare effects, and the development of related
effects protocols.   These subject areas  provide a
complex,  interrelated,   multidisciplinary  technical
program,  the objective  of  which  is to ensure the
continued  protection   of  the  public  health  and
welfare  as it relates to  the  mobile source  emissions
control   program, and  the  effects that fuels,  fuel
additives,  advanced  control devices,  and  alternate
power systems have thereon.  The development and
review of  this  integrated  program,   which  is the
responsibility of the  Special Studies  Staff, includes
the review, evaluation, and reporting of data collected
and proposals for necessary action.

   Registration—Additives used in gasoline introduced
into  interstate commerce must be registered with
EPA.   At the present time, more than 325 such
additives  are  registered  in  a number  of chemical
classifications.

   Emission  Characterization—Characterization  of
both regulated  and non-regulated exhaust pollutants
and the effect of  fuel components and fuel additives
thereon  are  essential to provide the  preliminary
information  required  to assess  potential  adverse
effects  of such  fuel  components or  additives  on
emissions and emission control  device performance.
In addition, detailed characterization of exhaust prod-
ucts resulting from combustion of fuels with and
without  additives  and  products emanating  from
catalytic control devices and alternate power systems
is  essential in order to provide the data necessary to
conduct meaningful health effects studies.
   A result of this program has been a reassessment
of the public health benefit  related  to the use of
oxidation catalysts on mobile sources and the attend-
ant increase  in levels of potentially  hazardous non-
regulated emissions.
   The  past  efforts  and  future research  emphasis
related to emission characterization are presented in
Table 5.

   Emissions  Effects Protocols— EPA may require that
tests  be  conducted  by any  fuel or fuel  additive
manufacturer to ascertain the  effects of such fuel or
fuel additive on  both emissions and control  device
performance.  Such tests are to be based on protocols
specified  by  the  Administrator  and are largely ex-
tensions of the research programs outlined previously
under Emission Characterization.
   The  past  efforts  and  future research  emphasis
related to emissions effects protocols are presented in
Table6.

   Surveillance—Collection of commercial fuels, crank-
case oils,  and diesel  fuels,  and their subsequent
analysis are essential  to ensure  both the validity of
the registration information upon which the research
program  is based  and the dependable performance of
consumer-operated advanced  control  systems that
already have  been shown to be sensitive to particular
fuel and  oil components and additives.  This activity
is just getting under way.

   Health  Effects   Assessment-Tbe   Agency   is
developing the health intelligence necessary to ensure
that public health is protected by the mobile  source
emissions control program.   Available serviceable
toxicologic models and human exposure study tech-
niques can provide a reasonable data base for decision-
making.   Although  a  hierarchical screening  system
has not been developed, there  is  no doubt that such a
system would be most valuable  in obtaining answers
 40
                     ANNUAL REPORT 1973

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                         Table 5.  EMISSION CHARACTERIZATION MILESTONES
           Major program component
                                                                 Quarter of calendar year
                                                  1972
             1234
                           1973
1234
             1974
1234
             1975
1234
             1976
123
Characterize gaseous emissions—current vehicles—
 as function of fuel and fuel additive composition
Characterize gaseous emissions—rotary engines
Characterize gaseous emissions-diesel engines
Characterize gaseous emissions as function of fuel
 and fuel additive composition—advanced proto-
 type vehicles
Operate in-house engine and chasis dynamometers
Characterize particulate emissions as function of
 fuel and fuel additive composition—current
 vehicles
Characterize particulate emissions as function of
 fuel and fuel additive composition—advanced
 prototype vehicles
Characterize particulate emission—rotary engines
Characterize particulate emissions—diesel engines
Survey and characterize 1975 model California
 vehicles
Effect of fuel composition and fuel additives on
 atmospheric visibility



              — — — — o-

Planning	
Implemented o
Completed
Continuing
                        Table 6.  EMISSION EFFECTS PROTOCOL MILESTONES


Major program component

Emission control device performance protocol
Regulated emissions (HC, CO, I\IOX) protocol-
LDMV3
Particulate emissions protocol LDMV
Non-regulated emissions protocol— rotary
engines
Visibility effects protocol
Gaseous emissions protocol diesel engines
Particulate emissions protocol diesel engines
Quarter of calendar year
1972 1973 1974 1975 1976
1234 1234 1234 1234 1234
A
Initial .Update
o *


o



Planning
Implemented o-
                Completed
Continuing 	>-
aLDMV-Light Duty Motor Vehicle
Research Activities
                                                                 41

-------
to key health questions more rapidly.  The program
gives  immediate  priority  to toxicologic assessment
(using  simple and  relatively rapid techniques)  of
compounds  of palladium,  platinum, and ruthenium
believed  most likely  to  occur in auto  emissions,
since this information  needs to be available before the
large-scale introduction of catalytic converters with
the potential for introduction of novel  pollutants into
the environment.  The currently funded 3-year pro-
gram is summarized in Table 7.
 International Activities
   The Special Studies Staff serves as a focal point
 for coordinating the international activities of NERC-
 RTP.   In addition, it  provides direct assistance con-
 cerning criteria and other documentation.

   World Health  Organizat/on-Tbe WHO has desig-
 nated  EPA/ORD as its  International Reference Center
 for Air Pollution Control.  The Assistant Administra-
 tor has delegated  the  responsibility for meeting this
 obligation to NERC-RTP

   In  meeting  this obligation, NERC-RTP's Quality
 Assurance and  Environmental Monitoring Laboratory
 serves as an  International  Aerometric  Data  Bank,
 receiving, processing, analyzing, and publishing data
 received from international laboratories via WHO. In
 cooperation  with  the Organization  for Economic
 Cooperation  and  Development, QAEML assists and
 directly participates  in the development of WHO
 standardized measurement  methodology for  moni-
 toring air pollution.
   The Special Studies Staff,  at  WHO'S requests,
 contributed to WHO air criteria and guideline docu-
 ments via annotated outlines and draft manuscripts.
 The  staff provided   draft  annotated  outlines for
 Air Quality Criteria and Guides for Nitrogen Oxides
 and Guidance Manual for Planning, Implementing and
 Evaluating Air Pollution Regulations  and Control
 Programs,    Draft documents  were  also provided
 representing  the  U.   S. contribution  to WHO for
 environmental  health   criteria  for manganese  and
 polychlorinated biphenyls.  Additional documents of
 this  nature are to be  provided on a requested basis.

   Organization  for  Economic  Cooperation  and
 Dei/e/op/7?e/7f-NERC-RTP's  Deputy Director  is the
 official U. S. delegate to the  OECD Air Management
 Sector  Group.   Activities of this  group concern air
 pollution   problems   that   transcend   international
 frontiers, the international interchange of air pollution
 monitoring and research data, the economics of air
 pollution  control  policies  and  their  implications
 relative to international trade, and needs for additional
research and international cooperation to meet these
needs.
   The Special  Studies Staff assisted OECD in 1973
by evaluating WHO'S Air Quality Criteria and Guides
for Urban Air Pollutants  and  by preparing,  with
cooperation from OAQPS,  a case history on the use
of criteria in developing standards for the control of
sulfur dioxides in the United States.
   NATO's Committee on  the Challenges of Modern
Society—The NATO Committee on the Challenges of
Modern Society  (CCMS) conducts eight designated
pilot studies, one of which deals with air pollution.
The  United States  is the pilot nation for this study,
with the Federal  Republic of Germany and Turkey as
co-pilot nations.  The following four major tasks were
concluded in  May 1974:
   Task  I. Assessment  of  ambient  levels of sulfur
oxides and particulate pollution  and sources for both
present conditions  and  projected  growth.  (NERC-
RTP's Quality Assurance and Environmental Monitor-
ing Laboratory)
   Task  II. Selection of  appropriate mathematical
diffusion   modeling  techniques  to   relate   source
emissions   to  ambient   air  levels.   (NERC-RTP's
Meteorology  Laboratory)
   Task  III.  Development  of   air quality  criteria
documents for  sulfur  oxides,  particulates,  carbon
monoxide, nitrogen oxides, and photochemical  oxi-
dants   and  related  hydrocarbons.   (NERC-RTP's
Special  Studies Staff)
   Task  IV.  Development  of  control   technology
documents for pollutants cited above.  (NERC-RTP's
Control Systems Laboratory)
   The  Director   of  the  Special  Studies  Staff  is
chairman  of the air  quality  criteria panel.   The
required documents in Task 111 were formulated by an
international  panel with the U. S.  representatives being
responsible  for   drafting   the  documents and  the
Special  Studies Staff having responsibility for having
the documents reviewed and completed to publishable
form.
   In 1973, the NATO/CCMS document Criteria for
Nitrogen  Oxides  was  completed  and  published;
Criteria for  Photochemical  Oxidants and  Related
Hydrocarbons  was  begun  in   1973  but was  not
published until early in 1974.
   The  commitment to this project  has been met;
future activity is expected to be minimal.


   World  Meteorological  Organization-The  NERC-
RTP's Meteorology Laboratory works closely with the
World  Meteorology Organization  (WMO).  WMO is
now utilizing QAEML's aerometric  data bank  for
storage  and  retrieval  of aerometric data  concerning
rainfall  and atmospheric turbidity.
42
                     ANNUAL  REPORT  1973

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Table 7. ACHIEVEMENT MILESTONES FOR TASKS TO ASSURE THAT PUBLIC HEALTH IS PROTECTED
Research and development task grouping
Estimate LD$Q and LC$Q doses of noble &
and in appropriate concentrations
Identify organs and tissues that may be at
risk through single and repeated exposures
of rodents via ingestion and inhalation of
noble metal compounds
Estimate no-effect level of noble and base-
metal compounds on allergic disease and
immunologic competence:
• immediate and delayed by hypersensi-
tivity in animals
• small airway resistance in guinea pigs as
a model for pulmonary irritation and
aggravation of asthma
Estimate no-effect level of noble-and base-
metal compounds on irritation of eye and
respiratory tract:
• in vitro assay using conjunctiva! and
respiratory cell structures
• in vivo test using rabbit tear lysozyme
or corneal models
Compare pulmonary carcinogenicity of base-
or noble-metal compounds and of lead com-
pounds in association with polynuclear aro-
matics:
• develop in vitro screening systems
• test with in vivo hamster intratrachial
model
Compare no-effect levels of lead and noble-and
base-metal compounds on acute infectious
respiratory disease
• in vitro alveolar macrophage screening
• in vivo mouse pulmonary infectivity
Compare relative mutagenic potential of base-
or noble-metal compounds with lead com-
pounds:
• in vivo screen using hamster cytogenic
model
• in vivo screen using host-mediated assay
• in vivo dominant lethal test in mice
Compare relative toxicities of noble-and base-
metal compounds with lead compounds using
selected enzymatic assays
Assess embryotoxicity potential for noble-and
base-metals on gross developmental anomalies in
mice
Document any changes in human pollutant bur-
dens
Quarter of calendar year
1972 1973 1974 1975 1976
1234 1234 1234 1234 1234
II 1
1 1 4
1 1 1
4 1 4
444
4 4 4

4 4
4 444
4 4 4
0 44 4 4
0 4 4 4 4
4 4 4
4 4 1
4 4 4
4 4 4

Research Activities
43

-------
Table 7.  ACHIEVEMENT MILESTONES FOR TASKS TO ASSURE THAT PUBLIC HEALTH IS PROTECTED
                                                 (cont.)
Research and development task grouping
Investigate subtle physiologic changes (including
enzyme activity, hypersensitivity, and cyto-
genetic anomalies) induced by exposure to
catalyst attrition products
Investigate irritation effects of catalyst attrition
products in humans
Test protocol to assure public health
Quarter of calendar year
1972 1973 1974 1975 1976
1234 1234 1234 1234 1234
* 1 1
4 1 *

°

Implemented t> 	 OomnlPtion T
   Special Foreign  Currency Program—The Special
Foreign Currency Program  (SFCP) provides for con-
tracts  for  cooperative research.   Contracts  exist
between NERC-RTP(via EPA'sOffice of International
Affairs (OIA)) and  institutions  in Poland, India, and
Yugoslavia.  In Poland, SFCP studies are being  done
on control  systems  and biological effects related to
effluents from  coal-fired  boilers and on biological
action  of radionuclides.  In India, radionuclide effects
are also being studied.  There is interest in studies on
air pollution  control  and on biological response to
manganese.   In Yugoslavia, studies are  under way
relative to  biological effects of  several  metals and
pesticides.  There is  interest in studying emissions and
pollution control in  selected industries.
   NERC-RTP's staff participates as members of OIA-
SFCP project teams. These teams have been engaged
in such scientific fields as health effects, monitoring,
modeling, and control technology.  Team members
have visited Yugoslavia, Poland, and Pakistan.

   Internationa/ Cooperative Agreements—Since 1969,
there has been a cooperative agreement  between the
Federal Republic of Germany and the United States
to coordinate research in five specified areas: health
effects of automotive exhaust on  humans; health and
environmental effects  of lead,  including monitoring
programs; effects of airborne nitrogen oxides; effects
of airborne carcinogens; and health effects of asbestos,
including the development of  monitoring methods.
   Since 1961,  there has been a United  States-Japan
Cooperative Science Program. NERC-RTP is involved
with both a working group on trace metals and a proj-
ect  on comparison of cardiorespiratory  illness in
matched groups in the two countries.
   In February  1972, the protocol for a cooperative,
tri-partite,   cadmium-health  effects   project   was
developed and  agreed  upon  for the  United States-
Japan-Sweden  Tri-Partite  Studies.    This protocol
requires  each country to conduct  research, on  a
collaborative basis, on  measurement  and biomedical
aspects of exposure to cadmium.
   A  United States-U.S.S.R. Environmental Agree-
ment, established in 1972, relates in part to biological
and genetic effects of pollutants.
   Initial  discussions and scientific  information ex-
change will  involve epidemiology, mutagenesis,  and
heavy  metals.  NERC-RTP and other  United States
agencies will participate.
   The overall U. S. objectives  of all three programs
would be to make  it  possible  to get the maximum
information input from the ongoing research in these
area in the Soviet Union.  It is clearly possible that the
United States, by working with the Soviets, can both
encourage an increase  in the  quality and quantity of
environmental health research in both countries and
have access  to the research results produced by the
Soviet scientists.  This would  significantly increase
the research data base  upon  which  all  regulatory
decisions  are made.  The long-term benefit, both to
the United States and  to the Soviet Union, would be
a broadened information base on effects to environ-
mental chemicals and  physical factors  on  humans so
as to permit the best  possible regulatory decisions.
   Another   part  of  the  Agreement  deals  with
stationary  source air  pollution control technology.
It is  desirable  to have exchanges of air pollution
research   and   development  information  on  the
following subject areas:

   •  Sulfur  oxides  and particulate  from  thermal
      power plants.
   •  Gasification of coal and oil.
   •  Demetallization of residual fuel oil.
 44
                                                                           ANNUAL REPORT  1973

-------
   •  Economic  studies  of  desulfurizing  methods.
   •  Physiochemical  analysis  of  components  in
      emissions  from the  iron  and  steel  industry.
   •  Ice fog control.
   •  Catalytic  oxidation  process for  sulfur oxide
      control.
   •  Control of emissions from coke ovens.
   •  Desulfurization  and ash removal from coal by
      mechanical cleaning.
   •  Identification and  control  of  emissions  from
      coal- and oil-conversion processess.

   It was agreed that, on problems requiring negotia-
tions  with  industry  groups  or  other  government
agencies in the  United States, EPA would be respon-
sible for coordination.
   There is  a United  States-France cooperative pro-
gram  on "Physical  Modeling Tests" with the French
Meteorological Service and  NERC-RTP's Meteorology
Laboratory.
   There  is also a United States-Spain  study, the
Almaden Project, aimed  at evaluating the  effects of
mercury,  including the  study  of   biological  and
environmental aspects.   The project is  just getting
under way.

   Economic Commission  for Europe—The Control
Systems  Laboratory  has cooperated with the ECE
in conducting a seminar on  air  pollution control in
the non-ferrous smelting industry.
   Other Foreign Contracts—The Special Studies Staff
is also  involved with contracts involving Holland, The
United Kingdom, and Sweden:


   • A contract with the International Flame  Re-
     search Foundation at its Research Station in
     Ijmuiden,  Holland, relates  to  control of emis-
     sions  from  coal  combustion.    Programmed
     through  Fiscal Year 1975, the  contract involves
     NERC-RTP's Control  Systems  Laboratory.
   • A contract with the  Esso Petroleum Company
     Research  Center,  Abingdon,  Berkshire,  U.K.,
     involves  the  chemically active fluid-bed com-
     bustion process. Programmed  activity will con-
     tinue through Fiscal  Year  1975, possibly into
     Fiscal  Year  1976, with  NERC-RTP's  Control
     Systems  Laboratory.

   • A contract with  the Karolinska  Institute  in
     Sweden  involves annual updating,  via supple-
     ment,   of   the  document,   Environmental
     Cadmium.  NERC-RTP's Special Studies Staff is
     party to the contract.

   The  Special Studies  Staff  will  prepare periodic
status  reports  for  describing  and  summarizing  all
international  activities associated with  NERC-RTP.
It  is anticipated that  there will be increased activity
with WHO, SFCP, and cooperative agreements.
Research Activities
                                               45

-------
   Human
   Studies
Laboratory

-------
                                       •

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        Human
       Studies
Laboratory
HUMAN STUDIES
LABORATORY
•••
•^
m^m
•m

EPIDEMIOLOGY BRANCH

BIOMETRY BRANCH

BIO-ENVIRONMENTAL
MEASUREMENT BRANCH

BIO-ENVIRONMENTAL
LABORATORY BRANCH

-
CLINICAL STUDIES
BRANCH
Studies of the cardiopulmonary, psychophysiologic,
metabolic,  and immune responses of humans in con-
trolled environmental  laboratories are conducted at
the Human Studies Laboratory branch located in the
University of North Carolina Medical Center.
OVERVIEW OF HSL'S MISSION

   The mission of the Human Studies Laboratory is to
define the influence of environmental stress on human
health so that appropriate steps can be taken to meet
the  requirements  of  the  Clean Air  Act.   The
Laboratory must also recognize and define new prob-
lem areas in environmental health as new technologies
emerge.  In addition,  it must provide technical assist-
ance to the Agency during pollution emergencies and
during public hearings on control activities.
LEGISLATIVE MANDATE

   HSL's  research program  is designed to  meet the
legislative mandate  expressed in Section 103 of the
Clean  Air Act and in  Section 241  of the Public
Health Service Act.   Specific sections of the Acts are
shown below  followed  by brief descriptions of the
types of  actions  taken  by  HSL  in support of the
mandates.

   "RESEARCH,   INVESTIGATION,  TRAINING,  AND
   OTHER ACTIVITIES
   "Sec. 103. (f) (1)  In carrying out research pursuant to
      this Act, the  Administrator shall give special emphasis
      to research on the short- and long-term effects of air
      pollutants  on public health and welfare.  In the
      furtherance of  such research, he shall conduct  an
      accelerated research program—
        "(A)  to improve knowledge of the contribution of
      air pollutants to the occurrence of adverse effects of
      health, including, but  not  limited   to,  behavioral,
      physiological, lexicological,  and  biochemical effects;
      and
        "(B) to improve knowledge of the short- and long-
      term effects of air pollutants on welfare.
        "(2) In carrying  out the provisions of  this sub-
        section the Administrator may—
        "(A) conduct epidemiological studies of the effects
      of air pollutants on mortality and morbidity;
        "(B) conduct clinical and laboratory studies on the
      immunologic, biochemical, physiological, and the toxi-
      cological  effects including carcinogenic, teratogenic,
      and  mutagenic   effects  of  air  pollutants;.   .  ."

   In support of Section  103, HSL  develops and
conducts  studies  designed  to  define  relationships
between  specific  undesirable health effects and en-
vironmental pollutants,  either  individually or  in
combination.    This research  includes biochemical
laboratory studies, clinical studies on human subjects,
and  epidemiological studies of human  populations.
Knowledge of  the  effects of  short-  and  long-term
exposure  to   environmental  pollutants provides  a
basis for establishing national environmental or emis-
sion standardsfor those pollutants or source categories
that  endanger  human health or welfare,  In addition,
the HSL research  program is designed to evaluate the
health benefits of improved air quality resulting from
Human Studies Laboratory

-------
the establishment  of  emission standards.   This  pro-
gram  is also concerned with the  decrement in health
resulting from  any future relaxation in air  quality
standards in response to the energy crisis. Analysis
of the economic costs resulting  from adverse health
effects of pollution  is an integral  part of the  HSL
program.
   Epidemiologic  studies  on the effect of radiation
on  humans  come under  the  broad  mandate of
Section 241 of the Public Health Service Act, which
is quoted in part below.

   "THE PUBLIC HEALTH SERVICE ACT"
   "Sec.  241. Research and investigations  generally.
      "The Surgeon General shall conduct  in the Service,
      and encourage, cooperate with, and render assistance
      to other  appropriate public  authorities,  scientific
      institutions, and  scientists in the conduct of, and
      promote the coordination of,  research, investigations,
      experiments, demonstrations,  and studies relating to
      the causes, diagnosis, treatment, control, and preven-
      tion of physical and mental diseases and impairment of
      man . . . ."

   Under the  broad  mandate of Section 241,  HSL
studies the  effects of ionizing radiation exposure on
humans  in cooperation  with  the Atomic Bomb
Casuality Commission  research program  in  Japan.
HSL  places major  emphasis  on evaluating the risk of
adverse  irreversible biological effects from exposure
to  various  levels  of different  pollutants  and  in
delineating  the time  lapse  between exposure  and
disease (latent  effects).   Other studies conducted by
the  laboratory are concerned with the  effects of
non-ionizing radiations to which the general  popula-
tion  is  exposed.     HSL resources  committed  in
support of these acts are shown in Table  8.
 ORGANIZATION

   The HSL  is divided into the Office of the Director
 and  five Branches.   The  Office of  the  Director
 coordinates all  Laboratory  activities, develops long-
 and short-term research goals, and periodically reviews
 the progress of Laboratory programs.
   The Epidemiology  Branch studies the effects of
 pollution on  human health  and searches for predis-
 posing  factors  that  worsen  or contribute to the
 development  of various diseases.   In addition, the
 Branch assesses the impact  upon health and welfare
 of improvements  in environmental quality  resulting
 from efforts to control pollution.
   The Biometry Branch is responsible for the design
 and analysisof research studies and provides statistical
 design  and analysis, computer programming,  and data
 processing services.  The Branch conducts research in
statistical and'computer-oriented areas related to the
mission of the Laboratory.
TableS. SUMMARY OF RESOURCES FOR HUMAN
STUDIES LABORATORY FOR FISCAL YEAR 1974a

Category
Clear Air Act,
Section 1 03
Public Health
Service Act,
Section 241
Total
Funds,
$103
8461.0

299.0


8760.0

Positions
104.0

9.0


113.0
Approximate
percent
97

3


100
aDoes not include $3.4 million of special energy appropria-
tions.
   The  Bio-Environmental Measurement Branch con-
ducts  a comprehensive program of  environmental
measurements of pollutants in controlled laboratory
environments and  in ambient polluted environments.
These measurements are related to the physiological
and pathological responses of human  subjects exposed
to environmental pollutants in bio-medical laboratory
studies  and of  selected segments of the populations
in epidemiologic studies.
   The  Clinical  Studies  Branch conducts laboratory
studies  to detect and define effects of environmental
pollutants  on  human  health,  to verify correlative
epidemiological  findings, and  to  develop or improve
methodology for application to human health effects
studies  in the laboratory and in community settings.
   The Bio-Environmental Laboratory Branch (BELB)
works   in cooperation  with the other  Branches  of
HSL to describe human metabolic response to pollut-
ant exposure. The  BELB program  includes performing
chemical  analyses of  environmental  and  biological
samples, as well as conducting  research to determine
appropriate methodology  for  the analyses  of trace
environmental or  biological specimens.  The  Branch
is also  developing  methods for determining the level
of  human  exposure  to various pollutants.   The
objective  is to  demonstrate a dose/response relation-
ship  for exposure  to a given pollutant species and a
specific metabolic parameter prior to permanent  or
serious  injury.
PHYSICAL  FACILITIES

   The  Human  Studies  Laboratory has facilities at
NERC-RTP  and  in  Chapel  Hill,  North  Carolina.
Laboratories in both locations are equipped with the
most modern analytical instruments,  including gas/
50
                     ANNUAL REPORT 1973

-------
 liquid chromatographs, an atomic absorption spectro-
 meter with  heated  graphite  atomizer,  ultra-centri-
 fuges, disc gel and slab electrophoresis devices, radio-
 active strip scanning devices, and liquid scintillation
 spectrometers.
   Twenty-three  Community  Health and Ambient
 Monitoring Program (CHAMP) stations are being up-
 dated and equipped with the  best technology  avail-
 able in sensors complemented by automatic electronic
 data  acquisition  with remote  magnetic  tape storage
 and "on-call" telemetric  output  and  visual field data
 inspection.
   The  Clinical  Studies  Branch  is   located in the
 Clinical Environmental Research Laboratories build-
 ing  on  the  periphery of  the  University  of North
 Carolina  Medical Center  complex  in  Chapel Hill.
 This  special-purpose building was constructed specifi-
 cally to  assist  in  fulfilling EPA medical  research
 objectives and to provide special-purpose laboratories
 and support  areas. These special-purpose laboratories
 include:

   •  Controlled  human  exposure facilities in which
      varied exposures to air pollutant concentrations
      or noise levels can be produced.
   •  Cardiovascular research facilities for validating
      measurement techniques and for obtaining car-
      diovascular data from studies  on animals and
      humans.
   •  Psychophysiology facilities  in which human be-
      havioral and psychophysiologic studies are con-
      ducted.
   •  Microbiology  facilities in which effects of en-
      vironmental stress  and human  immune mech-
      anisms are studied.
   •  Pulmonary physiology facilities in which new
      techniques for human pulmonary function meas-
      urement are developed and  validated.
   •  Clinical metabolism facilities in which  routine
      and   specialized  human   clinical  chemistry
      analyses are performed.
   •  Pulmonary research facilitiesat the  Frank Porter
      Graham Child  Development Center in  Chapel
      Hill, the exercise physiology laboratory, and the
      pathology   laboratories  in  which specialized
      research is conducted.

   In addition to the  above facilities,  HSL  has an
optical reader for directly processing  health question-
naire data  onto magnetic tape and computer terminals
that provide direct access to EPA's Computer Center
atNERC-RTP.
MAJOR PROGRAM AREAS

   HSL research activities are in two major program
areas: field epidemiological studies in ambient pollu-
tion exposure  situations  and  clinical  (laboratory)
studies  on  human  subjects under  experimentally
produced  exposure conditions.   The various studies
are integrated or complementary in a manner designed
to provide the broadest possible  response to the needs
of the Agency.
Epidemiological Studies

   Current  Activities— Studies   conducted   in  13
communities of the Community Health and Environ-
mental Surveillance System (CHESS) provide gradients
of exposure to total suspended particulate, respirable
suspended   particulate,  sulfur   dioxide,  nitrogen
dioxide,  suspended nitrates, suspended  sulfate, and
photochemical oxidants.   Also, autopsy tissues were
collected in each of the CHESS cities to derive new
health intelligence  concerning  the  levels  of trace
metals and other  multimedia  toxic  substances  in
humans.   Those epidemiological activities consist of
measurements  of sensitive, acute, and chronic health
indicators  in  demographically similar  populations
exposed  to a  gradient of  ambient levels of  specific
air  pollutants.    Because  data  are  being collected
during years  in  which communities achieve state
implementation  plans, these studies may document
the health  benefits of pollution control.  CHESS may
also  assess  the  health impact  of changing  energy
patterns as power plants shift from low- to high-sulfur
fuels, and from gas and oil to coal.
   Epidemiological  studies also involve  the  orderly
installation, check-out, calibration, and maintenance
of the Community Health Air Monitoring Program
(CHAMP) measurement devices.  CHAMP  is a key
element  of  the  CHESS program and is  designed to
provide short-term  measurements of air  quality ex-
posures within the CHESS areas.  Data are recorded
on site by automated  methods compatible with EPA
computer standards and are retrieved through a sys-
tem  employing sequential, automatic  polling of all
field stations.  If emergency atmospheric conditions
exist  in any area at the time of polling,  an alarm  is
sounded  and the emergency condition  is displayed
for reporting to Federal and local agencies.
   Two  computerized, mobile  clinical  laboratories
have been designed and are now  being constructed.
They will  give  a  new level  of sophistication to
epidemologic studies in Fiscal Year 1975.

   Major   Accomplishments—Ma]or   field   study
accomplishments during the fiscal  year period of this
report involved the CHESS program.   The CHESS
program  included 31 neighborhoods  in 6 areas of the
country:  the interurban area of New York and New
Jersey; the State of Utah;  the cities  of Chattanooga,
TN,  Birmingham, AL,  and Charlotte, NC; and the Los
Human Studies Laboratory
                                              51

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 Angeles  basin.  The six health indicators under sur-
 veillance  in  these  neighborhoods  included  chronic
 respiratory disease  in adults, acute lower respiratory
 disease in children, frequency of daily asthma attacks,
 pulmonary  function  of school children, residue  of
 cumulative  pollutants  in  human tissue, and  daily
 aggravation of symptoms in subjects with pre-existing
 heart and lung disease.
   Major  research involving a specific group of pollut-
 ants  culminated  in  the publication  of  the  EPA
 monograph, Health Consequences of Sulfur  Oxides:
 A Report from CHESS, 1970-1971.   (EPA-650/1-
 74-004).
   Draft  reports from  field studies of  the  CHESS
 program for 1971-1972 for the CHESS neighborhoods
 in  New  York and in  the  Southeastern cities  were
 completed on the  effects  of respirable particu lates.
 These studies reflected the  benefits of improved air
 quality as pollution control plans were implemented.
 Analyses and  preparation   of  reports  pertaining  to
 nitrogen  dioxide and  oxidants  are underway for
 1971-1972   in  the  Los   Angeles   Basin  and  in
 Chattanooga.
   Data  from the  Southeastern  cities suggest that
 particu lates in  the presence of low  levels of sulfur
 dioxide are associated with decrements in pulmonary
 function and increases  in  lower  respiratory disease
 morbidity  in school children.  The most important
 finding  resulting from  the  New  York-New  Jersey
 area studies  was that  the  health  indices of chronic
 respiratory disease in adults, lower respiratory disease
 in children, and pulmonary function results did not
vary across the four New Jersey communities exposed
to similar  long-term pollutant levels.  The finding
confirmed the belief that people  living in areas with
similar pollution levels would demonstrate  similar
 health indices.
   The first phase of an epidemic logic study confirmed
that  an  increase in congenital anomaly rates  had
occurred at  a military  base at which a significant
amount of  radar surveillance is used.  This study will
be expanded to obtain data  on  factors other than
Blood sample for chromosome analysis is drawn from volunteer exposed to ozone in laboratory test.

52                                                                         ANNUAL  REPORT  1973

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 radar  exposure  that might  explain the  observed
 increase.

   Future  Research Emphasis-Jhe  CHESS program
 will continue  to  seek  data delineating  the  dose/
 response   effects   of  exposure  to  pollutants  and
 describing   the  human  health  benefit  of control
 actions.    Timely  reporting of  CHESS results  will
 enable the Agency to evaluate the impact of existing
 standards,  the need  for  revised  standards, and  the
 desirability of taking new control action.
   The completion of a  new research facility  will
 facilitate rapid  dose/response studies of human ex-
 posure to gaseous pollutants, and  particulates.
   Other   major  efforts  will  be directed toward:

   • Completion   of    reports   on   the   health
      consequences  of   exposure    to  respirable
      particulates, nitrogen dioxide,carbon monoxide,
      and oxidants.
   • Completion  of analyses  of  health and exposure
      data  collected under CHESS field studies during
      1972-1973.
   • Cooperation with National Science Foundation,
      National  Bureau of  Standards,  and  Atomic
      Energy  Commission in  establishing a National
      Tissue Bank.
   • Refining the estimate  of the dose/response
      curve relating to the development of thyroid
      tumors in children exposed to diagnostic doses
      of radioactive iodine.
   • Preparation  of a report on  the  benefits of con-
      trolling  automobile pollution that will include
      a review of past studies and propose research to
      obtain better benefit estimates.
   • Investigation of the  health effects  associated
      with the normal operation of sewage plants and
      the   application  of  effluents  in agriculture.
   • Completion of installation and conversion to the
      Univac 1110 computer  system to increase the
      quantity of  data processed per unit of time.
Clinical Studies

   Current Activities—Human clinical studies include
investigations of  the  effects  of short-term,  low-level
exposure  to carbon monoxide, ozone, and nitrogen
oxides.  Physiological measurements include cardio-
vascular response to pollutant exposure under varying
degrees of physical stress (exercise).
   Clinical studies have been initiated to investigate
growth and  development of children's lungs  in low
pollution  environments  using pulmonary  function
measurements. The results of this study should pro-
vide a baseline for comparing pulmonary function in
clean versus polluted environments.
Volunteer is asked to exercise  during exposure to
ozone  in  environmental chamber to test pollutant
effects.
   Other  studies  have  been  initiated  to measure
changes  in  pulmonary  function  and  to  identify
chromosomal aberrations from controlled short-term,
low-level  exposure to the photochemical oxidants
(nitrogen  oxides  and ozone) that are known to be
present  in the polluted  atmospheres of  our  cities.
   The effects of noise levels on humans is also under
investigation.
   The  Clinical  studies  program  also  involves the
design, procurement,  fabrication, and installation of
human  exposure facilities and  the  equipping of a
mobile clinic.  The facilities allow researchers to con-
trol temperature  and humidity and to maintain the
desired levels of aerosols and gases, either singularly or
in combination.
   Physiological  sensors  incorporating  most  recent
advances in the state-of-the-art have been  incorporated
in these facilities.  The operation of these physiological
monitors requires the combined talents of physicians,
engineers, biologists,  psychologists, and technicians.
Human Studies Laboratory
                                               53

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Pulmonary function  of volunteer  exposed  to  ozone in laboratory is  tested to evaluate pollutant effects.
   Clinical  Study  Major Accomplishments—Studies
of non-smokers exposed to 0.5 ppm of ozone for 6
hours indicate a significant decrement in ventilatory
function  measurements.  A high positive correlation
was found  between severity of irritation  symptoms
(chest pain, cough, phlegm, etc.)  and  decrement in
ventilatory  function measurements.  These findings
reflect results similar to  those from animal exposure
studies.   Smokers,  on the other hand, showed no
decrement in ventilatory function after exposure to
0.5 ppm of ozone for 6 hours.
   Preliminary results from  controlled exposure to
oxidants  suggest that ambient air concentrations of
the pollutants in a number of our  cities could be
sufficiently high to cause identifiable  chromosomal
aberrations in humans.
54
                     ANNUAL  REPORT 1973

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Experimental
     Biology
  Laboratory

-------

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Experimental
           Biology
    Laboratory
EXPERIMENTAL BIOLOGY
LABORATORY

•«
^•n
•••

PATHOBIOLOGY RESEARCH
BRANCH

TOXICOLOGY BRANCH

MOLECULAR BIOLOGY
BRANCH

NEUROPHYSIOLOGY AND
BEHAVIORAL RESEARCH
BRANCH

TECHNICAL STUDIES
BRANCH
 Studies  to  determine biological effects of low-level
 microwave  irradation are conducted by  the  Experi-
 mental Biology Laboratory.
OVERVIEW OF

EBL'S  MISSION

   Experimental Biology Laboratory  research is  di-
rected  toward  studies  relevant to the development
of environmental standards for the protection of hu-
man health and welfare,  particularly as such standards
relate to  gaseous and  particulate  air pollutants,  to
ionizing and nonionizmg radiation,  and to interactions
among pollutants. Studies using laboratory animals or
biological  preparations complement human epidemi-
ological and clinical programs by validating data from
human studies, providing clues to new human studies,
developing toxicitydata  for extension to humans, and
indicating the potential  harmful effects of new pollu-
tants. These studies require the coordinated contribu-
tion of  chemists, engineers, and representatives of a
wide variety of biological disciplines. The Laboratory
possesses  particular expertise in  the  areas of animal
toxicology, radiation biology, neurobiology, and mi-
crowave engineering.
LEGISLATIVE MANDATE

   EBL's programs support Section  103  of the Clean
Air Act and Section  241  of the Public Health Service
Act. The relevant sections of the Acts are shown be-
low followed by brief descriptions of the types of ac-
tions taken by EBL to support them.

   "RESEARCH,   INVESTIGATION,  TRAINING,  AND
   OTHER ACTIVITIES
   "Sec. 103. (f) (1) In carrying out research pursuant to the
     Act, the Administrator shall  give  special emphasis to
     research on the short- and long-term effects of air pol-
     lutants on public health and welfare. In the further-
     ance of such  research, he shall conduct an accelerated
     program—
     "(A) to improve knowledge of the contribution of air
     pollutants to the  adverse effects of health, including,
     but not limited to, behavioral, physiological, toxico-
     logical, and biochemical effects; and
     "(B) to improve  knowledge of the short- and long-
     term effects of air pollutants on welfare.
        "(2) In carrying out  the provisions  of this subsec-
     tion the Administrator may —
     "(A) conduct epidemiological studies of the effects of
     air pollutants on mortality and morbidity;
     "(B) conduct clinical  and laboratory studies on the
     immunologic, biochemical, physiological, and the toxi-
     cological  effects including carcinogenic, teratogenic,
     and mutagenic effects of air pollutants; . . . ."

   EBL programs in support of Section  103 include
studies  on the effects  of  the  regulated pollutants
(ozone, nitrogen  oxides, sulfur  oxides,  and  particu-
lates) and  the non-regulated pollutants  (particulate
sulfate and  nitrate, fine  particulates from  industrial
 Experimental Biology Laboratory
                                               57

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sources,  trace  metals, etc.) using appropriate whole
animal, organ, cellular, or sub-cellular models. Particu-
lar emphasis has been given to the effects of pollutants
on  pulmonary defense  mechanisms  and  pulmonary
carcinogenesis  and to the  influence of  interactions
between  coexisting pollutants  and various  physical
factors upon these pulmonary responses. The poten-
tial  mutagenicity  of photochemical  oxidants is also
under  investigation. Programs are under development
to examine the effects  of  prenatal and neonatal, as
well as adult, exposure to photochemical oxidants and
carbon monoxide upon  subsequent growth and devel-
opment  (including  development of behavioral  pat-
terns).

   "THE PUBLIC HEALTH SERVICE ACT
   "Sec. 241. Research and investigations generally
       "The Surgeon General  shall conduct in the Service,
   and encourage, cooperate  with, and render assistance to
   other  appropriate  public  authorities, scientific institu-
   tions,  and scientists in  the conduct of, and promote the
   coordination of,  research, investigations, experiments,
   demonstrations, and studies relating to the causes, diag-
   nosis,  treatment, control, and prevention of physical and
   mental diseases and impairment of man, including water
   purification, sewage treatment, and pollution of lakes and
   streams . . . ."

   The "causes      of      diseases" cited  in Public
 Health Service  Act Section 241 include  ionizing  and
 non-ionizing radiation.  The responsibility to provide
 Federal  guidance on all radiation  matters  affecting
 health and the authority  to  establish  environmental
 standards  for the  protection of the general  environ-
 ment  from radioactive material  rests with EPA.  EBL
 programs related to ionizing radiation are centered on
 tritium  and  krypton-85, two  of the major  effluents
 from  nuclear  fuel  reprocessing plants,  and  are de-
 signed  to  provide  a   more  secure  data  base  for
 prediction of potential health effects than is currently
 Table9. SUMMARY OF RESOURCES FOR EXPERI-
 MENTAL BIOLOGY LABORATORY FOR  FISCAL
                    YEAR 1974
Category
Clean Air Act,
Section 103
Public Health
Service Act,
Section 241
Total3
Funds,
$103
1896

1180


3076
Positions
20

47


67
Approximate
percent
62

38


100
 aDoes  not include $0.5  million of special energy appropria-
 tions.
available. The Laboratory also conducts an extensive
program on  the health  effects of  electromagnetic
non-ionizing  radiation.   Emphasis  is placed on the
potential mutagenic, teratogenic, and neurobiological
effects-and mechanisms of interaction at the cellular
and  subcellular  level-of  radiations  of  frequencies
ranging from  500 megahertz (MHz) to 10 gigahertz
(GHz).  Table  9 presents a  summary  of resources
employed for EBL during Fiscal Year 1974.
ORGANIZATION

   The  Office  of  the  Director ensures integrated
application  of the multi-disciplinary  expertise avail-
able within  the five  branches  in  research  projects
designed to develop information pertinent to formu-
lation and revision of environmental  quality criteria
in support of human health studies.
   The  Pathobiology  Research  Branch  is primarily
concerned with the investigation of air pollutants as
they relate  to acute  and chronic respiratory disease
and  pulmonary carcinogenesis, and as they affect an
organism's mechanisms of  defense  against infectious
agents,   using  whole  animal   and in  vitro model
systems. Particular emphasis is given  to interactions
between  chemical,  biological,  and physical  insults.
The Branch also has responsibility for  development of
rapid  throughout  in  vitro  screening  systems  for
determining  the  relative   toxicity  of  gaseous  and
particulate air pollutants.
   The   Toxicology  Branch   investigates  the gross
teratologic, reproductive, developmental, and genetic
effects  of  a  variety  of   environmental  pollutants,
together with  late effects  such  as tumor production
and life  span  shortening. Originally concerned largely
with  the  toxicology  of   radioactive  materials,  the
Branch  has extended its activities  to studies of the
biological effects of nonionizing radiation and of the
interactions  between  radiation  and other  existing
environmental pollutants.
   The  Molecular Biology  Branch's principal  interest
is the  interaction of radio frequency and microwave
radiation with  biological  systems  at the subcellular
and molecular  level, with  particular  attention being
given to  effects on  the genetic material  and other
macromolecules and on the organelle and cell mem-
branes.  The Branch's  expertise in microbiology,  bio-
chemistry,  and  physical  chemistry and  in  electron
spin  resonance techniques is  also  being applied to
studies  on the  toxicity  of tritium  and heavy metals
and on the extrapulmonary toxicity  of photochemi-
cal oxidants.
   The   Neurophysiology   and  Behavioral  Research
Branch  investigates possible adverse  effects  of envi-
ronmental  contaminants on  the nervous system in
 58
                      ANNUAL REPORT  1973

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animal models  and develops research methodology in
the area of neurobiology applicable to the study  of
human  populations.  The  members of  the Branch
function  as  an interdisciplinary team  to study re-
sponses  of behavioral,  electrophysiological,  neuro-
humoral,  and  related  physiological  parameters  to
exposure  to chemical and physical stressors including
air pollutants,  pesticides,  and  ionizing  and  non-
ionizing  radiation. The  Branch  serves as the focal
point for coordination of neurobiologic research for
NERC-RTP.
   The Technical Studies Branch provides support to
the Laboratory through the development and mainte-
nance  of equipment and instrumentation necessary
for biological effects research, particularly in the area
of electromagnetic non-ionizing radiation. The Branch
also coordinates the Laboratory's computer services
and provides computer programs to support biologi-
cal activities.  The  Branch  conducts research in the
dosimetry of non-ionizing radiation and the applica-
tion of dosimetric  techniques to biological studies.


PHYSICAL FACILITIES

   The  Laboratory possesses facilities for exposure of
laboratory animals (via inhalation) to gaseous materi-
als and  aerosols under  controlled  conditions of air
flow, temperature, and  humidity and  for exposure
(via inhalation and whole-body exposure) to radio-
active gases (currently krypton-85)  over long periods
under beta-infinite cloud conditions.
    Facilities that permit  exposure to a range of radio
and radar frequency radiations are available or under
construction.  These facilities  include two large  ane-
choic chambers for use at S- and X-band frequencies,
both with environmental control systems; a strip-line
facility  for whole-body exposures of small mammals
over the  VHP, TV, and UHF  ranges;  and numerous
custom-built airline systems for irradiation of cellular,
subcellular, and molecular preparations at frequencies
upward from 200 MHz.
    Electrophysiological   recording   instrumentation
and behavioral testing  chambers  (housed  in  RF-
shielded and/or sound-attenuated rooms), with associ-
ated laboratory computers,  are available for neuro-
biological studies.
   For  measurement of  concentrations of  paramag-
netic  species   and  free  radicals, an  electron  spin
resonance  spectrometer with a  9-inch  electromagnet
and a  double  cavity  is available.  The  system  also
includes frequency measuring equipment for  precise
g-value  determinations to characterize  and identify
unknown species.  Additionally, the associated  vari-
able temperature unit  permits  determination of free
radical  reaction rates and  matrix trapping ability from
80° K to 370° K.
MAJOR PROGRAM AREAS

Air Pollutants

   Research   on  pulmonary  defense  mechanisms
utilizes animal model systems to investigate effects of
air  pollutants  on  the  upper and  lower  respiratory
system as reflected by  such parameters  as physical
clearance rates, persistence of bacteria, and exacerba-
tion  of existing  infections.  EBL research  has shown
that  hydrogen chloride  gas  has no effect upon the
aforementioned  parameters  but does produce ana-
tomical  changes in  the  nasal cavity.  In  relation to
pulmonary infection,  EBL  studies  show that the
concentration  of nitrogen dioxide  (NO2) is of much
greater importance than the  time of exposure to the
pollutant. Exercise was found to enhance the suscep-
tibility to pulmonary infection of mice  exposed to
ozone. During a sequential  exposure to ozone and
No2,  when  ozone was  given  first,  there  was  no
additive effect of N02; whereas, when NO2 was  given
first, there was an additive effect to ozone. This result
suggests an immediate tolerance  development wherein
the ozone has  a stronger tolerance-inducing  effect
than  does N02-  In  another EBL  study, N02 in
concentrations of greater than 10 ppm for 30 minutes
failed to alter  complement or immunoglobulin levels
in rabbits, either in vivo or in vitro.  An  antialveolar
macrophage  serum  was  successfully  developed, but
preliminary results have indicated that its non-specific
serum effect  may  override  its  specific  effect  upon
macrophages.
   Extramural  research in support of EBL activities
includes  studies designed  to evaluate  the relative
effects of exposure of mice to peak versus continuous
concentrations   of  NO2-  Parameters studied  have
included  resistance  to  viral  and bacterial infection,
immunoglobulin and  complement levels,  antibody
titers, and pulmonary  pathology.  Currently,  effects
on  cell-mediated immunity  are  under investigation.
Longer term  studies in  rats  and monkeys are being
extended to newborn animals to examine the effects
of  age  on the  genesis of  emphysema  from  N02
exposure.
   Reports on the  potential  mutagenic role of  ozone
have led to reevaluation of its extrapulmonary ef-
fects. Initially,  confirmation  of  ozone's apparent
ability to induce chromosome aberrations in circulat-
ing  lymphocytes  is being  sought.  Following  this
study, effects  on transmissable translocations will be
examined.  A  limited  experiment  to examine the
potential for  induction of extrapulmonary tumors is
also being conducted.
   Implication of acid  mists and sulfate  particulates
as correlates  of respiratory  disease  through  human
epidemiological  studies led to the development of a
program  to evaluate factors  affecting the toxicity of
Experimental Biology Laboratory
                                               59

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Patterned behavior in rats exposed to pollutants is analyzed using closed circuit television coupled with computer
methodology.
Small animal exposure facilities are used to test the health effect of gaseous and paniculate pollutants,

60                                                                       ANNUAL REPORT  1973

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fine particulate materials. The role played by particle
size and composition, and by interacting factors such
as humidity, temperature, and the presence of sodium
chloride is  being  studied  in suitable animal models
using sulfates of  known composition  and mixtures
generated through  the  interaction of sulfur dioxide,
ozone, and olefins.
   Benzo[a] pyrene  (BaP)  is being  used  as a model
compound  in studies of the part played  by environ-
mental  polycyclic hydrocarbons in  the induction of
pulmonary  cancer. Preliminary  studies  have involved
endotracheal administration of  BaP, either alone or
combined   with   metallic  oxides.  Parallel studies
employ  airborne  particulates  containing hydrocar-
bons collected from ambient air.
   Work on the  effects of  oxidant gases on rabbit
alveolar macrophages in vitro led to the development
of systems,  using  alveolar  macrophages  and human
lung  fibroblasts   in  tissue  culture, for  the   rapid
evaluation  of the relative cytotoxicity of environmen-
tal  pollutants. Originally  applied  to  trace  metals
(cadmium,  vanadium, nickel, manganese, and  chro-
mium)  known to occur in fine particulates in ambient
air, these evaluative systems are now being used to
examine fly ash  and  other fine  parciculates  from
industrial effluents,  and noble metal compounds and
other  attrition products from  automobile catalytic
converters.  The systems  have  also  proved useful in
permitting  rapid  identification  of  biochemical and
cytological  lesions  that  might impair  critical cell
functions such as biosynthetic or phagocytic activity.
   Future  plans call for expansion  of studies on the
extrapulmonary effects of three regulated  air  pollu-
tants, ozone, nitrogen dioxide, and carbon monoxide.
These studies will concentrate initially  on the effects
of  prenatal and  neonatal exposure on growth and
functional  development, particularly of the cardiovas-
cular and central  nervous systems, of small laboratory
animals. Research at EBL will continue to be focused
on  the  elucidation of the health effects of pollutant
interactions, expanded  to include such pollutants as
particulate  sulfate  and  particulate  nitrate.   Such
studies  are  needed  to  permit the   continued assess-
ment of the adequacy of environmental  standards and
to provide assurance that new technologies present no
environmental health hazards.
 Ionizing Radiation
   Programs  in  radiation health effects research are
presently confined to  tritium  and  krypton-85,  two
major effluents from the reprocessing of nuclear fuel.

   Tritium— The principal areas of research on tritium
during the reporting  period  have been  the effects of
tritiated  water  (HTO)  on embryos, on  the central
nervous system, and on tumorigenesis, life  span, and
reproduction.  The common focus of this research is
to determine the adequacy of the existing standards
for the exposure of the population to tritium.
   The embryonic and fetal stages are considered the
most  radiosensitive  periods of life. A current extra-
mural  study  using pre-implantation  mammalian em-
bryos is designed to  identify the  radiosensitive stages
in the developmental  process and  to correlate pre-
implantation  and developmental anomalies with post-
implantation  death.  The early zygote stage has been
shown to be the most sensitive. Comparisons of the
relative biological effectiveness (RBE) of tritium and
strontium beta radiations, X-radiation, and  cobalt-60
gamma radiation in  producing these end-points  have
shown that the RBE for tritium is  unity.
   During  early  development, the  central  nervous
system is particularly vulnerable  to irreversible dam-
age. Previous work has shown that the brain size and
weight of new-born  laboratory animals continuously
irradiated during the gestation period  were signifi-
cantly lower than in unirradiated controls and  that
the reduction was  linearly proportional to dose.  A
study has now  been  undertaken to determine if there
are associated neurochemical changes—specifically  in
levels of  the  neurotransmitters, norepinephrine (NE)
and  dopamine  (DA)   and in  concentrations  and
activities  of the enzymes, monoamine oxidase (MAO)
and  acetylcholinesterase (AChE). MAO, AChE, and
DA contents of  the  brain were  unaltered  by HTO
treatment.  The  NE  concentration  in  brains  from
irradiated animals increased significantly between 2
and 45 days  after birth at total  doses as low as 66
rads.  Increased NE  levels  have been associated with
behavioral abnormalities such as hyperactivity.
   Production of tumors and non-specific shortening
of life are two of  the principal  delayed effects  of
whole-body irradiation. A long-term, dose/response
study  of female  rats exposed  continuously to HTO
over the  gestation period  and of their offspring has
been  underway for  more  than 2 years. During the
reporting  period, data collection  on  the  parental
generation  was completed. The  life span  of  dams
receiving total doses of from 66 to 660 rads was
significantly  shortened  over  that  of  unirradiated
female rats.  An increased incidence  of mammary
neoplasia  following  doses  of 330 and 660  rads was
also observed.
   In real life, humans are  exposed to environmental
tritium from conception throughout the life span, a
period that would normally include the production of
another generation.  Genetic  damage resulting from
continuous low-level  radiation may  accrue  and pos-
sibly  be  manifested and  magnified in subsequent
generations. Studies involving the continuous expo-
sure   of  rats  to HTO from conception   through
production of  the  third (F2> generation have  been
Experimental Biology Laboratory
                                               61

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performed. The exposure levels used were 2, 20, 200,
and 2000 times the standard (MPCW) for continuous
exposure  to  HTO  by an  individual in  the general
population. The results of the rat study showed that
lifetime parental exposure produced effects in the ^2
generation at levels 10 to  100 times lower than  those
required  for the same effects after in utero exposure
alone.  Statistically significant reductions in the rela-
tive brain weights of F2 neonates were noted at  doses
as low  as 20 times the MPCW.
   Behavioral studies are planned to complement the
gross   teratologic  and  neurochemical  research de-
scribed above. Studies are underway to  ascertain the
age  segment  of  the population  most  sensitive to
chronic  HTO  irradiation  using reproductive,  hor-
monal, and neurochemical end points.

   Krypton-85— Research  into  the  physiological be-
havior and radiation effects of krypton-85 is designed
to  provide  data for a  realistic assessment of the
hazards of exposure to this noble gas.
   Whole-body partition coefficients and kinetic be-
havior of 85Kr are being studied in several species. In
guinea  pigs,  the  saturation  and desaturation  curves
have  been shown  to  be multi-exponential, usually
with 4 components with half-times of  0.25 to 2.2
minutes,  6 to 12 minutes, 21 to 42 minutes, and 88
to  178  minutes.  The whole-body  weight  partition
coefficient  [(^Ci85Kr/g guinea  pig)/(,uCi85K.r/cm3
air)] for  adult guinea pigs was found to be 0.1444
(Standard  Deviation  =  0.0148).   Comparison  with
preliminary data from  rats  and fragmentary partial
body data from humans indicates that saturation/de-
saturation rates are inversely related to the size of the
animal.
   The equilibrium concentrations of 85Kr in various
organs  and  tissues  of  guinea pigs and  hamsters
breathing 85Kr at known concentrations  are  being
determined  to evaluate radiation  doses  delivered to
radiosensitive  tissues. In vivo weight partition coeffi-
cients  have been obtained for blood and 22 organs
and  tissues  in  guinea  pigs.  The highest coefficients
(for  bloodless tissue)  were: omental  fat, 0.4213;
subcutaneous  fat, 0.4056;  thymus,  0.2588; lymph
nodes, 0.1375; bone  marrow, 0.1342; and  adrenals,
0.1017.
   The median lethal exposure for 85Kr administered
to guinea pigs by  inhalation with  the outside of the
body protected, together  with the associated  hema-
tology  and  pathology,  is being studied  to  correlate
tissue  distribution  findings with effects. The 30-day
median lethal exposure has  been  determined  to be
4450  microcuries   per  cubic centimeter per  hour,
which  corresponds to estimated doses of 316 rads to
bone marrow, 340 rads to whole body, and 7876 rads
to lung. The gross  clinical and necropsy observations
were consistent with  death  from the hematopoietic
syndrome,  but lung  injury was  dominant in animals
that survived for more than 30 days.
   Guinea  pigs (in the  natural state or clipped), rats,
and Chinese hamsters  are being exposed  to   Kr in
beta infinite geometry  to determine the acute median
lethal  exposure  for  each  species and  the associated
hematological  and  pathological  changes.  The skin
dose necessary to cause clinically observable damage
is  of  particular  interest.  To date,  guinea pigs have
been exposed  at surface doses up to 15,000  rads. The
only effects observed  were  some erythema, mild  to
severe beta burns on the ears, and mild burns on the
nose.  The  animals are being retained for long-term
observation.
   Future  plans  call  for chronic  exposure studies
designed to develop a dose/effect  relationship for
induction of skin cancer in rats and, possibly, Chinese
hamsters.
Nonionizing Radiation

   EBL's programs in non-ionizing radiation research
are conducted as part of a multi-agency "Program for
Control of Electromagnetic  Pollution of the Environ-
ment:  The  Assessnr 3nt  of Biological  Hazards  of
Non-ionizing  Elect-omagnetic   Radiation"   coor-
dinated by the Offict of Telecommunications  Policy.
   Animal  models (whole animals and cellular, sub-
cellular, or molecular preparations as appropriate) are
used   to   investigate   potential   damage—including
genetic, biochemical, immunological,  and neurobio-
logical effects—from  exposure to radio  and  micro-
wave   frequencies similar  to  those  found   in  the
environment. Studies are designed to identify poten-
tial harmful effects, to establish the exposure levels at
which  these  effects are  elicited, and to delineate the
mechanisms of physical alterations. These studies will
provide a  data base for the promulgation of standards
governing  the  exposure of  the population to  non-
ionizing radiation.
   Attempts  have been  made to confirm reports that
microwave radiation will inhibit  the growth of bac-
terium, E.  co//'. The phenomenon, if real, is of great
potential significance. No inhibition  or enhancement
of growth  that could not be attributed to tempera-
ture changes could be demonstrated in studies of £
co// exposed at 1.7, 2.45, and 68 to  74 GHz.  The
effects of  changing  the substrate and the  strain  of
bacteria are now being examined.
   Isolated rat liver mitochondria  have been irradi-
ated with  2.45 GHz of radiation at power densities of
10   and   50  milliwatts   per   square  centimeter
(mW/cm2) to  determine if an effect  could  be de-
tected  on  respiration and oxidative  phosphorylation
(ATP synthesis).  No effect  was found. The available
exposure  facilities,  however, dictated irradiation  at
62
                      ANNUAL REPORT  1973

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0.4 C,  a  temperature  at  which  mitochondria  are
biochemically inactive. A coaxial airline exposure
system  is  now being developed to allow exposure at
25°Cor37°C.
   The  possibility of interaction of microwave radia-
tion with macromolecules has been examined  using
bovine  serum albumin as the test material. Because
transient effects can be most  readily observed as the
sample  is  being  irradiated, a cross-beam  apparatus
consisting  of a  waveguide  irradiation  system  inte-
grated with the UV spectrophotometer used to detect
structural changes has  been developed. No significant
effect was observed at  1.7 or 2.45 GHz.
   An  increase  in the percentage of  chromosome
aberrations has  been observed in kidney,  lung, and
thyroid  cells  cultured  from Chinese hamsters irradi-
ated with 2.45 GHz of  radiation at a power  density of
200 mW/cm2 for varying times-and at 25, 50,  100,
150, and 200 mW/cm2 for a constant time. The per-
centage  of aberrations scored was dependent upon
time of exposure but apparently not dependent upon
power density. No dependence upon body tempera-
ture was observed.
   The  range of frequencies over which exposures can
be made continues to expand. Ongoing research using
a time domain reflectometer system is attempting to
identify anomalous absorption characteristics of bio-
logical materials at specific frequencies. In any event,
future work will ensure that  FM, VHP TV, and UHF
TV  frequencies,  as well  as  the S- and  X-microwave
bands,  receive adequate  coverage. These work areas
along with an  examination  of potential teratologic
and  neurobiologic effects and non-ionizing radiation
represent  the major areas of effort in the immediate
future.
Multiple,  Coexisting
Environmental Stressors

   Standards for the protection of the public  against
toxic environmental agents do not  usually consider
the  implications  of the  coexistence  of  multiple,
potentially  synergistic  stressors. The Experimental
Biology  Laboratory's  program has  been limited  to
studies on interactions between two  potentially syn-
ergistic  pollutants  from  among  the  multitude  of
potentially toxic agents and combinations thereof in
existence.
   Evidence suggested that cadmium and whole body
radiation  may act synergistically upon the  hemato-
poietic  system.  Coinsult  studies  in   rats  involving
intraperitoneal  injection of cadmium chloride  and
exposure to X-rays showed that the LDgo/so values
for 250 kVp X-rays decreased linearly  with increasing
amounts  of  cadmium  from 695  rads  (in  animals
receiving  no cadmium) to 491 rads  (in  a group
receiving 250 micrograms of cadmium  chloride twice
weekly for 30 days). Coinsults drastically altered the
number of circulating  red  and white blood cells and
significantly lowered the lymphocyte/neutrophil  ratio
for extended  periods  of  time.  Cadmium  chloride
definitely is a radiosensitizing agent and its biological
effect is synergistic.
   Currently underway is  a study  of  the long-term
effects of continuous exposure to lead and  tritium,
two pollutants  possessing characteristics that suggest
that they may  act synergistically. Both are transpla-
centally  transferred; the embryo and  fetus  are  par-
ticularly sensitive to both,  and exposure can  result in
reduced  litter size, stunted new-borns, sterility,  and
mental  retardation. Rats in EBL  studies are  being
exposed  to lead, tritiated water, and combinations of
the two from conception, through the production of
a  new  generation, to the adulthood  of  the P^
generation. Lead levels  of 5 to 50 ppm (100 and 1000
times  the Public Health Service standards for  drinking
water, respectively) and  tritium levels that are  2 to
200 times the standard  (MPCW) for  individuals in the
general  population  are used in the study.  The F-|
generation is being  observed for growth  and for the
development of  reflexes  and  spontaneous motor
activity. The f~2 generation will be examined for gross
teratologic manifestations  including pathology,  and
for postnatal development  in terms of reflex  develop-
ment,  spontaneous  motor activity,  coordination,
learning, and social behavior.
   Future  plans call  for studies of  more complex
exposure situations that can be expected to  occur in
the environment;  for  example,  the  neurobiologic
consequences  of simultaneous  exposure to 60-Hz
radiation, high  frequency noise, and ozone,  a condi-
tion found  in the vicinity of  high  voltage electrical
transmission lines.
Experimental Biology Laboratory
                                               63

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  Pesticides
       and
      Toxic
Substances
    Effects
 Laboratory

-------

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   Pesticides
              and
           Toxic
Substances
         Effects
 Laboratory
PESTICIDES AND TOXIC
SUBSTANCES EFFECTS
LABORATORY

•••
•••
•M

CHEMISTRY BRANCH

TOXIC EFFECTS BRANCH

BIOCHEMISTRY AND
PHYSIOLOGY BRANCH

ANIMAL RESOURCES STAFF
Studies to determine the effects of pesticides are
conducted in the field using a self-contained, portable
electroencephalograph. The EEC data are recorded on
tape cassette for computer processing at the Pesticide
and Toxic Substances Effects Laboratory.
OVERVIEW OF PTSEL'S MISSION
   EPA's Office of Pesticide Programs is responsible
for registering  pesticides  for use in the U.S. and for
establishing tolerance levels of pesticide residues in or
on  raw agricultural products. All research  conducted
at  NERC-RTP's  Pesticides and  Toxic  Substances
Effects Laboratory (PTSEL) is designed to provide a
foundation for decisions  made by EPA's registration
offices.  Data  from  acute, subacute, and chronic
studies in laboratory animals  and examinations  of
occupationally exposed  individuals are used to aug-
ment the  basic  scientific knowledge that  establishes
the need for continued registration  of pesticides  or
toxic substances in use in the U.S. Analytical chemis-
try  research  is  directed  toward the detection  of
toxicants in biological samples.
   Included  among  the   basic research  goals and
objectives  of the PTSEL  is the development, evalua-
tion, and application of instrumental techniques in a
program of basic and applied research in two general
areas:

   •  Elucidation  of the  mechanism  of  action  of
      pesticides  and their  metabolic products in  a
      variety of biological  substrates  and in appropri-
      ate   model  systems.  This  research  is accom-
      plished through the  use of magnetic resonance
      and spectrophotometric techniques.
   •  Development of a methodology and capability
      for  the  isolation,  detection, characterization,
      identification,  confirmation, and/or  quantita-
      tion  of  pesticide  residues, metabolites, and
      other chemical contaminants in human, animal,
      and  environmental  media.  This research  is
      accomplished,  in  part,  through  the use  of
      magnetic and quadrupole resonance  methods,
      spectrophotometric  techniques  (including infra-
      red, ultraviolet, and  atomic absorption), gas and
      liquid chromatography, and combinations  of
      chromatographic separations with sensitive and
      specific  detection systems and low- and high-
      resolution mass spectrometry.

   Newer and more comprehensive analytical  meth-
ods for the determination of  residues of pesticides
and their metabolic products are being developed  to
permit effective monitoring of the total environment.
The continued development of analytical methods in
pesticidal  research  is a  necessary  component  of
efforts to minimize human and animal exposure and
to preserve the quality of the environment.

LEGISLATIVE MANDATE
   Public  law  and policy  and the traditions of many
decades have directed governmental efforts to  assure
that the  Nation's  food supply  is safe, clean, and
Pesticides and Toxic Substances Effects Laboratory
                                            67

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wholesome. EPA,  committed  to full  enforcement of
these laws, has developed  criteria and  protocols for
pesticides and  toxic substances that  are effective,
workable,  and  enforceable.  The wholesomeness of
any food supply depends in part on the quality of the
total  environment: the soil, water, and air in which
the food is grown,  processed, and consumed. Contam-
ination  of  these basic natural resources by pesticide
residues and other pollutants can affect not only the
safety of food products but also other environmental
values such as water quality, wildlife  preservation,
and  outdoor recreation. EPA is actively seeking to
protect and manage  these resources in the interest of
greater human safety and welfare.
   The  statutory  authority   for  the regulation  of
pesticides and pesticide residues delegates the  respon-
sibility  for the registration of pest control materials
to EPA. In addition, the establishment of tolerances
for  pesticides  in  or on human food  and feed for
animals has been delegated in  part to  EPA and in part
to the Food and Drug Administration of the  Depart-
ment of Health, Education, and Welfare.
   If the proposed  use  of a  pesticide  will result in
residues on a food or feed crop, a registration for its
use  is granted  provided a tolerance  has  been estab-
lished by the regulatory authorities within EPA. The
regulation  of pesticide and pesticide residues by the
Federal government  encompasses those  pesticides or
residues involved in interstate commerce. Pesticides in
food supplies produced and used within a State are
under the jurisdiction of  that State.  The  various
Federal agencies work closely with their  State coun-
terparts in pesticide regulation and control, however.
   The  Federal  Insecticide, Fungicide,  and Rodenti-
cide  Act (FIFRA),  enacted  in  1947,  regulates the
marketing  of economic poisons and devices. This act
was amended in  1959, 1964, and more recently in
1972  to   include  the  Federal  Environmental Pest
Controls Act (FEPCA).
   The  term "economic  poison" is  defined  as any
substance  or  mixture of  substances  intended for
preventing, destroying, repelling, or mitigating forms
of  plant  and  animal  life  (such as  insects, rodents,
fungi, and weeds) or viruses (except  viruses on or in
living humans or other animals) and any substance or
mixture  of substances intended for use as  a  plant
regulator, defoliant,  or dessicant. Under  this  act no
pesticide chemical may be legally shipped in  inter-
state commerce for general use until it is known to be
safe  when used  as  directed  and  effective   for the
purpose claimed on  the label. Also, any residues that
may  remain in or on feed or food must not exceed
the safe tolerance levels established under the Food,
Drug, and Cosmetic Act (FDCA). FIFRA prohibits
the shipment in interstate commerce  of products that
are not registered  or are  adulterated or misbranded.
Products  that  are in violation  of the Act  may be
seized  and  criminal  action  instituted  against the
shipper of such products. In the  more recent amend-
ment  (FEPCA),  in  addition  to  directing labeling
restrictions for pesticide registration, EPA is responsi-
ble for: prescribing standards for the certification of
applicators of  pesticides; administering  the use per-
mits system; registering pesticide producers including
the  examination  of  records and books and the
inspection of plants; conducting research  and moni-
toring  activities including monitoring air, water, soil,
humans, plants, and animals; and regulating pesticides
imported to or exported from the country.
   EPA's  authority  for the establishment of toler-
ances  for  pesticides  in  or  on foodstuffs  or  raw
agricultural  products  is provided  by the Pesticide
Chemical  Amendment  (PCA)  of   the  FDCA.  The
paramount purpose of this Act is to assure the safety
of the  Nation's food supply. In part, this assurance is
provided by  ensuring that the residues remaining on
the food are safe  for  consumption and  by requiring
government  clearance before a pesticide  is used. This
Act  further  provides for seizure and  destruction of
agricultural commodities that contain pesticide  resi-
dues in excess of  established tolerances.  Where no
tolerance has been established, commodities carrying
residues  in excess  of  established working  levels are
also  subject  to seizure and destruction. This Act also
provides both for criminal  penalties for violation and
for legal injunctions to halt  use.  The FDCA outlines
the data and information to be furnished and the
procedures to be followed  for obtaining a pesticide
tolerance. Additional  procedures and more specific
data requirements  in the regulations ensure that food
safety  requirements are met prior to establishing a
tolerance. As provided  under  Section  408  of the
FDCA, tolerances  are established for raw agricultural
commodities,  not  for processed food.  If the residues
remaining in  a processed food have been removed to
the fullest extent possible through  good manufactur-
ing processes and do not exceed the tolerances on the
raw product, the processed product complies with the
law.  In general, the residues in  processed  food are a
fraction of the amount permitted on the raw agricul-
tural  product. To cover the residues of  pesticides
applied to or concentrated  in processed  foods, toler-
ances may be established under  Section 409 of the
Food Additives  Amendment  of  the FDCA, adminis-
tered by the  Food and Drug Administration. Because
the major use of pesticides  in  the U. S.  is  on raw
agricultural commodities, the overwhelming majority
of  established  tolerances  are   on these  products.
Ideally  pesticide  residue tolerances should apply to
ready-to eat food on the dinner plate because it is the
quantity  of  pesticide  actually  consumed that has
health  significance; however, tolerances established at
this  point in the food  chain would not be practical.
Therefore, a  point in  the distribution system where
 68
                      ANNUAL REPORT 1973

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 meaningful, corrective action can be taken to prevent
 the  consumption  of unsafe  amounts  of  pesticide
 chemicals  has  been selected. The  tolerance concept
 does  not anticipate, as a practical matter, that all
 foods will  contain  residues of all chemicals as high as
 the established  tolerance level, or  even  that all  of a
 single  food  will  always contain  a residue at  the
 tolerance level.

   Within the framework of registration of pesticides
 and of establishment of a  tolerance for pesticides,
 several  considerations must be  advanced:  the  regis-
 tered use and the tolerance level must be safe for the
 applicator, the  consumer, and the environment;  the
 level of residue must be safe if all  of a particular raw
 food containing residues at the  tolerance  level  is
 always  consumed;  the tolerance will not  reflect  the
 average residue on  a commodity  but will  represent
 the  maximum  residue  that  will remain under  good
 agricultural practice; the  tolerance  generally is estab-
 lished  on raw agricultural commodities and does not
 realistically reflect  the residue  in or on food as eaten;
 and the tolerance will be set only at levels reasonably
 required to cover  the  residue  likely  to occur as a
 result of good  agricultural practice. In the regulation
 of  pesticides.   EPA's  policy  is  to  minimize  the
 exposure  of the consumer and  the  environment to
 pesticides and  their residues in the interest of safety
 and reduced environmental contamination.

   To  register a pesticide and  to establish tolerances
 for the pesticide in or on raw agricultural commodi-
 ties, toxicity tests on the proposed material must be
 conducted  to  show that the directed use  of the
 product  would not  be  injurious  to humans, other
 animals, or the  ecological system when warnings and
 cautions are  carefully heeded. The extent of toxico-
 logical data  required to fulfill  these  requirements
 varies  with  the nature  and  proposed use  of the
 product. Biological  tests  under field and  laboratory
 conditions  must be conducted to determine  if the
 product will control the pests named  on the  label
 when used as directed without causing  a  significant
 adverse effect  to  the  crop or  the  property being
 treated. The basic  requirement for registering pesti-
 cide chemicals  and establishing tolerances is that the
 data and  other  information,  when  evaluated  as a
 whole,  will  establish the  safety  of the  proposed
 pesticide usage. This judgment is made by  personnel
 qualified by training and experience to  evaluate the
 safety of pesticide residues in or on food. In addition
 to  toxicological  requirements,  suitable  methods of
 analysis must be available for monitoring and enforc-
 ing  the proposed  registration. Sensitivity,  accuracy,
and precision in available analytical methods must be
evaluated in relation to the proposed use and toxicity
of the pesticide chemical.  Extraction and clean-up
procedures must efficiently remove and  recover resi-
dues from treated  samples from suspected cases  of
contamination.
   Data  requirements  for  registration  and for the
establishment of tolerances are  subject to continual
review in light of new scientific data and information.
Specifically,  advances  in  scientific  knowledge  are
continually evaluated to provide  the necessary criteria
for the conclusions made  concerning the safety  of
pesticides.
   Table 10 is a summary of the resources employed
by  PTSEL for  Fiscal  Year 1974 under the  Federal
Environmental  Pesticide Control Act of  1972, Sec-
tion 20.
Table 10.  SUMMARY OF RESOURCES FOR PESTI-
CIDES AND TOXIC SUBSTANCES EFFECTS LAB-
       ORATORY FOR FISCAL YEAR 1974

(Federal   Environmental   Pesticide  Control  Act of
                1972a-Section20)
Category
Pesticides
health effects
research
Pesticide iden-
tification
methodology
Toxic sub-
stances health
effect research
Quality assurance
Substitute pesti-
cides program
Totals
Funds,
$103
1539


335


180


257
830

3141
Positions
51


11


7


10
12

91
Approximate
percent
49


11


6


8
26

100
Includes Federal Insecticide, Fungicide, and Rodenticide Act.


ORGANIZATION
   The Pesticides and Toxic Substances Effects Labo-
ratory consists of two main functioning laboratory
groups: biological and physical.
   Physical  research  is conducted by the Chemistry
Branch, which is responsible both for the  study of the
metabolism   of  pesticides,  their  metabolites,  and
residual  products in  a variety of  biological  and
environmental substrates and for the development of
methodology  for  the  determination  of  pesticide
residues.  In  addition, quality assurance for methods
used  by  EPA and other  laboratories  is  maintained
through  the  use  of  a standard  reference repository
and  an  instrumental  workshop  for maintenance  of
equipment.
Pesticides and Toxic Substances Effects Laboratory
                                               69

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   Biological  research is conducted in two branches:
the Toxic Effects  Branch and the Biochemistry and
Physiology Branch.  The  Toxic  Effects Branch  is
responsible  for  investigating  short-  and  long-term
effects (including reproductive hazards)  of pesticides.
Teratogenesis and mutagenesis potentials of pesticides
are principally addressed  in  this area  as are acute,
subacute, and chronic studies on  laboratory animals.
Complete  pathological  facilities  are   available  for
examination  of  tissues  and organs of  test subjects.
The Biochemistry and  Physiology  Branch  predomi-
nantly investigates the mode of action  of pesticides
on  a  cellular  and subcellular basis using laboratory
animals.  Epidemiological  investigations on  occupa-
tionally  exposed  workers are  carried  out  in the
Branch's Field Studies Section located at Wenatchee,
Washington.   Field  investigations  on the  biological
effects  of pesticides and toxic substances are also
carried  out  at  Wenatchee.  The  Animal  Resource
Facility  maintains the animal quarters for the entire
NERC-RTP. Small laboratory animals, primates, and
selected  unusual experimental animals (e.g., voles) are
maintained for use in pesticide and toxic substances
research.
Effects of pesticides and toxic substances are studied
using laboratory animals.
Test dose of pesticide is administered to pregnant rat
using intubation technique.


   The  basic   purposes  of  these  facilities are  to
maintain  both  a level of applied research  in EPA's
areas of  responsibility and the means to respond to
high priority problems. The maintenance of several
fundamental areas of investigation allows the scien-
tists to respond quickly to inquiries either through
personal   experience  or  by  initiating  programs to
resolve the issues.


PHYSICAL FACILITIES

   The physical facilities of the Pesticides and Toxic
Substances  Effects   Laboratory,   located  both  at
NERC-RTP and in Wenatchee, are superior to most
laboratories of  comparable size and function. These
facilities  provide instruments for magnetic resonance
studies using spectrophotometry, for atomic absorp-
tion studies,   for  mass  analysis  studies,   and  for
combinations of chromatographic and  mass spectro-
scopy  techniques with integrated computer analysis
for efficient, reliable analysis of pesticide residues. To
maintain  the sophisticated electronic instruments, a
maintenance group provides  repair and modification
services to the  laboratory, to EPA pesticide contract
laboratories, to other Federal and State facilities, to
the  World  Health  Organization,  and  to   research
laboratories of foreign  governments.  The PTSEL
70
                      ANNUAL  REPORT  1973

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                                    ,
              -   --
MM «•  -•«•>»-  JM  _ _;jg_^ 'B«i 	I .   .^M
• •—-   ••-    *---•'•-
  • •      i^^ra^i*-  —•• ^ ,_^  ^MB^—
r
Teratogenic effects of pesticides are studied through
fetal necropsy.
repository,  containing approximately  450 standard
reference  pesticides,  provides  high-grade analytical
standards  for  U.S. and foreign laboratories conduct-
ing a wide variety of studies. To  support biological
studies, radioactivity  tracer equipment  for measure-
ment of low- and  high-energy emitters is available.
Complete  facilities  are available for the preparation
and analysis of radioactive samples.
MAJOR  PROGRAM AREAS

   Health effects research  on pesticides,  toxic sub-
stances, and  their  residues  includes: establishing the
chemical  identity  of  residues,  with  emphasis  on
significant  conversion products;  developing, improv-
ing,  and validating residue  measurement  methodol-
ogy; and conducting a  biological  research  program
aimed at evaluating the hazards of pesticides and their
residues and  conversion products by acquiring infor-
mation  on  the  effects of these materials on animals
and (ultimately) on humans.
Pesticide Identification

Methodology
   Tin,'  development  of  adequate methodology for
the  analysis  of  pesticides and  then  lesidues is  a
continuing problem requiting continual upgrading as
new  pesticides  are  introduced  or  usage  patterns
change. Multiple residue  techniques  that  will detect
many  pesticides simultaneously  have simplified the
regulatory  analytical  problems;  but, they have also
greatly  complicated  research and  development pro-
grams.  It  is often difficult to fit  a  pesticide into a
multiple-residue detection scheme without complicat
ing the scheme with the pesticides for which  it was
originally  developed.  A  large  group  of pesticides
coming into  increasing  use  is the anticholmesterase
agents,  that is, the carbamates and organophosphates.
These  agents are  just now  being  fitted into  such
multiple-residue  techniques.  Furthermore,  multiple-
residue  detection  techniques alone do not establish
unequivocally  the identity of the pesticide  residue,
particularly  if artifacts or interferences are  encoun-
tered.  Identity of the residue must be confirmed by
other methods, and  a variety of such  confirmatory
methods must  be available  for  the  many  different
pesticides  in use.
Pesticide-caused malformations in rat fetus are often
revealed through tissue magnification.
Pesticides and Toxic Substances Effects Laboratory
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   In  addition to the adaptation of present methods
to  new  chemicals and  the  development of  new
methods, improvements in the sensitivity, efficiency,
rapidity,  and simplicity  of  existing  methods  are
needed  to  improve the effectiveness of a monitoring
program.  A  quality  control  manual  for  pesticide
monitoring is being developed to assure the proper
analytical  control  of the  use  of  pesticides.  This
analytical manual  incorporates collaboratively tested
methods for determining pesticides and other chemi-
cal  residues  in air, water, and food; in  human and
animal tissues; and in other  environmental  media. At
the present time this  manual has been prepared for a
limited  number  of  substrates  and pesticide  com-
pounds; it  is  continually  being upgraded. New and or
improved analytical methods  and  detection systems
for  pesticides  are being developed  and  published
continually. Certain of these methods show promise
regarding their suitability for analysis of  substrates
Electroencephalogram changes have occurred in labo-
ratory monkeys after long-term, low-level exposure to
some pesticide.
relating to humans and the environment and are being
evaluated  for  inclusion  into  the  analytical  quality
control manual.
   In an effort to establish the identity of a residue in
the presence of  interfering materials, confirmatory
methods such as mass spectrometry are being utilized.
A  high resolution mass spectroscopy laboratory  has
begun  operation, and new methods for determining
trace   metals  in  human tissues  and excreta  that
combine  mass   spectroscopy  with  other  analytical
tools  including  gas chromatography and  atomic  ab-
sorption have  been developed. Through  the applica-
tion  of gas-chromatography/mass-spectroscopy tech-
niques,  various   pesticides have  been identified  in
human tissues, including Mirex, Oxychlordane, HCB,
Nonaclor,  and other  chlorinated  pesticides and con-
taminants such as polychlorinated biphenyls.
   Current  methodology for determining pesticides in
air is inadequate  both for sampling and for identifica-
tion  purposes.  Studies  are currently in  progress  to
correct  this situation by  amplifying the sampling
phase of the methodology. A new trapping system for
the further determination of pesticides in  air samples
has been laboratory tested and is  being examined in
the field.
   Improved methodology for the  determination  of
low-level  organo-phosphate exposure in humans  has
been developed  and is currently being field tested in
occupationally exposed  and normal populations. The
urinary alkylphosphate method has been shown to be
sensitive and reproducible for the  determination  of
low-level exposure in humans  and  is expected  to be a
welcome  addition  to  the  analytical methodology
currently available for defining such exposure.
   Environmental  samples (e.g., human tissues, wild-
life,  plants, and  water)  of dioxin contamination  of
range  land and  other areas  from  2,4,5-T exposure
have been analyzed to assure that this environmental
contaminant  has  not been introduced to the U.S.
through the normal use of herbicides.
   In many cases, residue from the use of a pesticide
comprises   not  only  the  chemical  applied but also
toxic  degradation or other conversion products that
may  be formed on exposure to light and weathering.
Metabolic   products  may  be  formed in animals and
deposited in edible tissues or milk.  This phase of the
research  program ensures that the composition  of
residues has been established  and  that the analytical
methodology developed will  measure all  lexicologi-
cally significant  residual  chemicals.  Metabolic  studies
of chlorinated pesticides have established the occur-
rence  of  a series  of metabolites  of the pesticide
Lindane  for  which analytical methodology  is cur-
rently  being developed.  The occurrence of these
metabolites of   Lindane, formed  in  the liver  by  the
drug metabolizing  system, forms  the basis of an in
vitro screening procedure for examining the biological
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                     ANNUAL REPORT 1973

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effects of pesticides and other exogenous materials on
drug metabolizing enzymes.


Quality Assurance

   A  quality control program currently in operation
includes:  the calibration and upgrading of instrumen-
tation, the standardization and distribution of materi-
als for  the  determinative  and  clean-up  steps in
pesticide  analyses, the distribution of  standard refer-
ence  material  for use in quality control,  and  the
evaluation  of  laboratory  procedures  and  perform-
ances on  standard reference materials. This  program
continually upgrades  methodology and laboratory
capability  in the 15  U.S.  laboratories involved in the
study of health effects of  pesticides. Each  year, over
3000 analytical  standards are  shipped to approxi-
mately  420 laboratories around  the world. All EPA
laboratories routinely draw samples from a repository
of standard reference materials for pesticide measure-
ment  that includes  over 400  currently  available
analytical standards.
   Quality  control studies for clinical biochemistry
and   pesticide  analytical  determinations  to  assure
reproducibility in data from various laboratories  and
various sections  of  the country give  assurance that
analytical  methodology will  be  available to  measure
all toxicologically  significant  pesticides  and that
variations will be minimal.


Health Effects of Pesticides
and Toxic Substances
   PTSEL's biological  research  program is  directed
toward evaluating the hazard of pesticide residues  and
their  conversion  products by acquiring information
on the effects of these  materials on  animals  and
(ultimately)  on  humans.  This   applied research is
directed  to establishing the safety of  pesticides  and
developing the scientific  foundation for EPA pesti-
cide  policies.  The research effort includes: develop-
ment  of data on  new types of pesticides to facilitate
EPA  guidance of commercial work,  more  detailed
examination of specific toxicological effects for their
impact on  safety evaluations,  examination and devel-
opment of new toxicological  methods for evaluating
product  safety,   and  resolution  of  conflicting  or
equivocal  data  for a  sounder evaluation of  the safety
of pesticides and their residues. With this informa-
tion,  environmentally safe pesticides   can  be regis-
tered, and safe tolerance  levels  and reliable enforce-
ment  policies  can be established. In all cases, animal
experimentation  should  produce measurable  param-
eters  that  can be  used   for logical  prediction  of
toxicity in humans. It is highly desirable to determine
how toxic substances affect humans so  that an animal
species that will provide  corresponding data useful in
the safety interpretation can be obtained.
   In brief,  EPA's health effects  research includes
studies of  the physiological and metabolic effects of
pesticides in biological systems including: the meta-
bolic fate  of the  compounds and  their  biochemical
reactions, the nature  of  the metabolic pathways and
an evaluation of their effects in terms of toxic action,
and  the  development of data on the direct effect of
pesticides on humans. In  this regard, previous primate
studies   on  the  effect  of  carbaryl,  a carbamate
insecticide,  have  shown  that  the EEC  is a sensitive
tool for  measuring biological effects. The  effect  of
several  pesticides  on  EEC  parameters  in squirrel
monkeys was investigated  and several  points  of
interest emerged:  the magnitude of alteration  of the
EEC  did not correlate with the relative  toxicity  of
the compound, similar EEC alterations were induced
by  chemically unrelated compounds, and carbaryl
was effective in altering the EEG of squirrel monkeys
at a dose that approximates the incidental or back-
ground   exposure  levels  in humans. This  low-level
exposure to carbaryl was also responsible for certain
changes in  animal  behavior. To correlate these effects
and  to  determine if they  can  be duplicated  in
humans,  portable EEG units were constructed and are
being field  tested in studies  of  people  who  are
occupationally or  incidentally exposed to pesticides.
   The delayed neurotoxic demyelinating potential  of
several organophosphate  pesticides  was  examined  in
animals.  High  concentrations  of  an experimental
organophosphate  insecticide were  found to induce
demyelination in  the  central and peripheral nervous
systems causing irreversible paralysis in the animals.
The  significance  of  this   unusual   effect from  a
potentially commercial organophosphate  pesticide is
being further investigated  to  determine its signifi-
cance to humans with regard to occupational expo-
sure and  ingestion of residues in food.
   In a  further  effort to examine  the physiological
effect of pesticides, the  impact of several chlorinated
pesticides  and contaminants  on reproduction  was
examined  in  laboratory  animals.   Studies  of  the
teratological  significance of  exposure   to  dieldrin,
Mirex, photodieldrin,  dioxin (several different isom-
ers), and  2,4,5-T were evaluated. In addition, in  vivo
and in vitro screening techniques were developed for
the evaluation of both  the neurotoxicity and the
biological  effects  of  pesticides on  liver function.
These techniques  have been useful in the  screening of
new pesticides prior  to  the initiation of long-term
studies to evaluate their toxicological significance.


Extramural Program
   The extramural  research grant and contract  pro-
gram authorized in part by FIFRA  and n part by the
Pesticides and Toxic Substances Effects Laboratory
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Public   Health  Service Act continues  to support
pesticide research activity  at universities  and non-
profit research organizations. The following program
titles indicate areas of  extramural study that provide
data to  augment  PTSEL's  research supporting the
regulatory activity of EPA:

   • Mode  of Action of Cyclodiene Insecticides-
     University of Arizona
   • Metabolic  Interactions of  Hormonal Steroids
     and  Chlorinate  Hydrocarbons—University  of
     Michigan
   • Mechanisms   of  Pesticide  Degradation-
     University of Wisconsin
   * The  Study  of  the  Ecology of  Pesticides-
     University of Miami
   • Actions of Pesticides and Other Drugs on Male
      Reproductive Organs—West Virginia University
     Medical Center
   • Effect of  Duck Hepatitis  Virus  on  Pesticide
     Toxicity—University of Georgia
   • Chemistry   and  Mode of  Action  of  Insecti-
     cides—University of California (Riverside)
   *  Biological  Hazards of Phototransformed  Pesti-
     cides-Stanford Research Institute
   •  Metabolism  of   Carbamate   Insecticides-
      University of Kentucky
   •  Role of Mixed Function Oxidases in Insecticide
      Action—University of Illinois
   •  Pesticide  Epidemiological   Field  Studies-
      University of Miami
   •  N.M.R. Studies on  the  Molecular Interactions
      of Pesticide of Environmental Concern—Oregon
      State University
   •  Investigation  of Pesticides  in  Human  Milk—
      Meharry Medical College
   •  Sensitive  Specific  Fluorescence  Immunoassay
      Methods for Detecting Organic Contaminants—
      IntelCom-RadTech
   •  Analysis  of  Clinical Specimens—University  of
      Miami

   Because  PTSEL  was   recently  relocated  from
Florida to North Carolina, accomplishments outlined
in  this report effectively cover only  the  period  of
January through September  1973; except  for the
extramural program,  which was consistent over the
entire year.
74

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 Chemistry
      and
   Physics
Laboratory

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                                                     OVERVIEW OF
                                                     CPL'S  MISSION
  Chemistry
              and
       Physics
 Laboratory
                  AND PHYSICS BRANCH
CHEMISTRY AND PHYSICS
LABORATORY

••
«•
••

AIR QUALITY MEASUREMENT
METHODS BRANCH

EMISSION MEASUREMENTS
RESEARCH BRANCH

ATMOSPHERIC CHEMISTRY
Studies, including simulations, of photochemical air
pollution are conducted using environmental chambers
and high sensitivity instrumentation at the Chemistry
and Physics Laboratory.
   NERC-RTP's  Chemistry  and Physics  Laboratory
(CPL) manages and conducts an intramural and extra-
mural research program that provides (1) techniques
and instrumentation for the measurement of atmos-
pheric  pollutants,  (2)  information  on the chemical
and physical transformations that pollutants undergo
in the atmosphere, and (3) information on the effects
of atmospheric pollutants on materials. While each of
these  program areas contributes directly to the  air
pollution control program, all are also closely interre-
lated: air pollution measurement techniques and  in-
strumentation research support atmospheric chemistry
and  physics  studies;  atmospheric chemistry and
physics studies provide information on what measure-
ment techniques are needed; and studies of the effects
of atmospheric  pollutants on materials provide infor-
mation  on  mechanisms  whereby pollutants can  be
removed from the atmosphere.
LEGISLATIVE  MANDATE

   The program of the  Chemistry and Physics Labora-
tory is totally responsive to the legislative mandates of
the Clean Air Act of 1970. The research and develop-
ment program  relates to many of the sections of the
Act as specifically detailed below.

   "RESEARCH, INVESTIGATION,  TRAINING, AND
   OTHER ACTIVITIES
   "Sec. 103. (a)  The Administrator shall  establish a na-
   tional research and development program for the preven-
   tion  and  control of air pollution and as part of such
   program shall —
     "(1) conduct, and  promote the coordination and ac-
     celeration of, research,  investigations, experiments,
     training, demonstrations, surveys, and studies relating
     to the causes, effects, extent, prevention, and control
     of air pollution; . . .
     "(3) conduct investigations and research and make sur-
     veys concerning any specific problem  of air pollution
     in cooperation with any  air pollution control agency
     with a view  to recommending a solution of such  pro-
     blem, if he is requested to do so by such agency or if,
     in his  judgment, such problem  may affect any com-
     munity or communities in a State  other than that in
     which  the source of  the  matter causing or contribut-
     ing to the pollution is located;"

   Each year the Chemistry and Physics Laboratory
conducts one or more field studies  of air pollution.
During  1973 a field  study was conducted  in Denver,
Colorado, in cooperation with the EPA Regional Of-
fice and the State air  pollution control agency.  The
study was part of a continuing effort to  determine the
nature  and source  of the  Denver "Brown  Cloud."
Chemistry and Physics Laboratory
                                              77

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Field studies were also conducted in Houston, Texas,
and Phoenix, Arizona, on photochemical oxidant, and
in St. Louis, Missouri, on photochemical oxidant and
sulfur oxides air pollution.
   Analysis of the data for the  Denver field study in-
dicated that the  "Brown Cloud" is  a two-component
plume:  one part,  close to the ground, contains major
amounts  of aerosol  from stationary sources;  and  a
second  part, above the first, contains aerosol largely
from automotive sources.
   In  1973  the Chemistry and Physics  Laboratory
developed specialized gas chromatographic  instrumen-
tation to measure "reactive" hydrocarbons in auto-
motive exhaust. This equipment was put into use in
EPA's Mobile Source Pollution Control Laboratory in
Ann Arbor,  Michigan.  Also in 1973, work was started
on  additional engine dynamometers  and a stationary
source simulator  to  increase the facilities which sup-
port  research  to  develop  instrumentation  and tech-
niques to measure pollutants emitted by these sources.
      "(4) establish technical advisory committees composed
      of recognized  experts in various aspects of air pollu-
      tion to assist in the examination and evaluation of re-
      search progress and proposals and to avoid duplication
      of research . . . ."

   The Chemistry and Physics  Laboratory  provides
administrative  management  of  the  Air  Pollution
Chemistry  and  Physics  Advisory  Committee.  The
Committee  met  twice in 1973: first  in  St.  Louis,
where the principal agenda item was the Regional Air
Pollution Study (RAPS) in progress there; and second
at the  University of Minnesota,  where the main sub-
ject was atmospheric aerosols.

         "(f) (1) In carrying out research pursuant to this
         Act, the Administrator shall give special emphasis
         to research on  the short- and long-term  effects of
         air pollutants on public health and welfare.  In the
         furtherance of  such research, he shall conduct an
         accelerated research program . .  .
         "(B) to improve knowledge of the short- and long-
         term effects of air pollutants on welfare."

    Research on the effects of air pollutants on mate-
rials and on atmospheric visibility is part of the pro-
gram of the Chemistry and  Physics Laboratory.  In
1973 an experiment was  begun in which several criti-
cal materials are exposed to simulated polluted atmos-
pheres  in chambers. The first phase  of this work will
be  completed  in  1974  and will eventually provide
quantitative dose/response information.


      "RESEARCH   RELATING   TO   FUELS   AND
      VEHICLES
      "Sec.  104.  (a) The Administrator shall  give  special
      emphasis to research and development into new and
      improved methods, having industrywide  application,
      for the prevention and control of air pollution result-
      ing from the combustion of fuels . . .
         "(b) In carrying out the provisions of  the section,
      the Administrator may—
         "(1) conduct and accelerate research and develop-
      ment of low-cost instrumentation techniques to facili-
      tate determination  of  quantity and  quality  of air
      pollutant  emissions,  including, but  not  limited to,
      automotive emissions; . . .
         "(3) establish and operate necessary facilities and
      test sites at which  to carry on the research, testing,
      development, and programming necessary to effectuate
      the purposes of this section;
      "AIR QUALITY CRITERIA AND CONTROL TECH-
      NIQUES
      "Sec.  108.  (a) (1) For the purpose of establishing
      national  primary  and secondary  ambient air quality
      standards . .  .
      "(2)  The Administrator  shall  issue air  quality cri-
      teria  for an  air pollutant within  12  months after he
      has included such  pollutant in  a  list under paragraph
      (1). Air quality criteria for an air pollutant shall accu-
      rately reflect the  latest scientific  knowledge  useful in
      indicating the kind and extent of all identifiable ef-
      fects  on public health or welfare which  may be ex-
      pected from the  presence of such pollutant in the
      ambient  air, in varying quantities. The criteria for an
      air pollutant, to the extent practicable, shall include
      information  on—
      "(A)  those  variable factors (including  atmospheric
      conditions)  which of themselves or in combination
      with  other  factors may alter the effects on  public
      health or welfare of such air pollutant;
      "(B)  the types of  air pollutants which, when present
      in the atmosphere, may interact  with such pollutant
      to produce an adverse effect on public health or wel-
      fare; and
      "(C)  any known  or  anticipated adverse effects  on
      welfare . . .
        "(c) The Administrator  shall  from time to time
        review, and as appropriate, modify, and reissue any
        criteria or information on control techniques issued
         pursuant to this section .  . . ."

   CPL initiated  a program on analytical  methods and
instruments to  be  used as portable analyzers  (dosi-
meters)  in health studies  to  aid  in  revision of air
quality criteria.  Effects  of air pollutants  on  organic
and  inorganic materials are investigated in environ-
mental chambers  to   supply input to  development
or modification  of secondary standards for  the cri-
teria  pollutants.   Research  on  new particulate  mass
monitoring instrumentation is in  progress to  provide
a more acceptable reference or equivalent method for
total  suspended   particulates.  Considerable effort is
going  into the development of the measurement tech-
nology for fine particles and for other pollutants that
may be considered candidates  for air quality  criteria.
The  formation and decay  of such non-criteria pollut-
ants also are under investigation.
      "NATIONAL AMBIENT AIR QUALITY STANDARDS
      "Sec. 109. (a) (1) The Administrator-
      "(A) within 30 days after the date of enactment of the
78
                       ANNUAL REPORT 1973

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       Clean  Air  Amendments of  1970,  shall  publish pro-
       posed  regulations prescribing a  national  primary am-
       bient air quality standard  and  a national secondary
       ambient air quality standard for each air  pollutant for
       which  air  quality criteria have been issued  prior to
       such date of enactment; and
       "(B) after  a reasonable time for interested persons to
       submit written comments thereon  (but no later than
       90 days after the initial publication of such proposed
       standards)  shall  by regulation promulgate such pro-
       posed  national  primary  and secondary  ambient air
       quality standards with such modifications as he deems
       appropriate . . .
          "(b) (1) ...Such primary standards  may be re-
          vised in the same manner as promulgated."
    Considerable efforts in support of present national
 ambient air quality standards  (particularly those for
 hydrocarbon/oxidants  and  nitrogen  dioxide)  are in
 progress in CPL to further define the atmospheric re-
 lationships  involving   hydrocarbons  and   oxidants.
 Evaluation  of  the  reference  method  for nitrogen
 dioxide was made,  and the 24-hour average colori-
 metric method was improved;continuous instrumenta-
 tion was also developed.
      "IMPLEMENTATION PLANS
      "Sec. 110. (a)  (1) Each State shall, after reasonable
      notice and public hearings, adopt and submit to the
      Administrator,  within nine months after the promul-
      gation of a national primary ambient air quality stan-
      dard (or any revision thereof) under section 109 for any
      air pollutant, a plan  which provides for implementa-
      tion,  maintenance, and enforcement of such primary
      standard in each air quality control region (or portion
      thereof)  within such  State. In addition,  such State
      shall adopt and submit to the Administrator (either as
      a  part of a plan submitted under the  preceding sen-
      tence or separately) within nine months after the pro-
      mulgation of  a  national ambient air quality secondary
      standard (or  revision thereof), a  plan which provides
      for implementation, maintenance, and enforcement of
      such secondary standard in each air quality control re-
      gion (or portion thereof) within such State. Unless a
      separate  public hearing  is provided, each State shall
      consider its plan implementing such secondary stand-
      ard at the hearing required by the first sentence  of
      this paragraph."
   CPL  is involved in a considerable effort to support
development  of chemical  and physical  air pollution
models for reactive  pollutants for  use in implementa-
tion plans, including site criteria of large area sources.
The transport of oxidants and the  rural oxidant prob-
lem  are  under  investigation. Empirical  relationships
between  hydrocarbons  and  oxidants  (such  as  upper
limit curves)  and relationships between hydrocarbons
and  nitrogen  dioxide are  being reviewed  and  evalu-
ated. Reactivities of  hydrocarbons and other  organics
have  been evaluated  for organic solvent  regulations
and transportation plans.
      "STANDARDS  OF  PERFORMANCE  FOR  NEW
      STATIONARY SOURCES
      "Sec. 111. (b) (1)  Within 120 days after the inclusion
      of a category of stationary  sources in a list under sub-
      paragraph  (A), the Administrator  shall publish pro-
      posed  regulations,  establishing  Federal standards  of
      performance for new sources  within such  category.
      The Administrator  shall afford  interested persons  an
      opportunity for written comment  on such  proposed
      regulations. After considering such comments, he shall
      promulgate, within 90  days after such publication,
      such  standards with such  modifications as he deems
      appropriate. The Administrator may, from  time  to
      time, revise such standards following the procedure  re-
      quired by this subsection  for promulgation of such
      standards. Standards of performance or revision there-
      of shall become effective upon promulgation."


   Extensive support is provided  by CPL in verifying
and  improving  the reference  methods for Category I
and  II  new  source performance  standards.  Perform-
ance  criteria have  been developed  for  extractive and
in-situ  instrumentation for determination of compli-
ance  with  sulfur oxide, nitrogen  oxide,  and opacity
standards for  a number of the  Category  I  sources.
Methods  development  continues  on  the  reference
methods  required  for  Category  III,  IV,  and V new
source performance standards.

      "NATIONAL    EMISSION   STANDARDS   FOR
      HAZARDOUS AIR POLLUTANTS
      "Sec. 112. (b) (1) (B)  Within 180 days after the inclu-
      sion of any air pollutant in such list, the Administrator
      shall publish proposed regulations establishing emission
      standards for such  pollutant together with a notice of
      a public hearing within thirty days. Not later than 180
      days  after such publication, the Administrator shall
      prescribe an emission standard for such pollutant, unless
      he finds, on  the  basis  of  information presented  at
      such  hearings,  that such  pollutant clearly  is  not a
      hazardous  air  pollutant.  The Administrator  shall  es-
      tablish  any such  standard  at the level which  in  his
      judgment provides an ample margin of safety to pro-
      tect  the  public  health  from   such  hazardous   air
      pollutant."


   CPL is  responsible  for  developing  the  analytical
methodology for the national emission standards for
hazardous  pollutants. Improved methods of sampling
and analysis are under  investigation or evaluation for
asbestos and  mercury.  There  has  been extensive de-
velopment  of  X-ray flourescent  methods for use  in
analyzing  a  number  of elements  possibly  having a
hazardous  nature.  Improved sampling and more rapid
analysis methods  for  polycyclic  organic matter are
under development.
      "PART  A-MOTOR  VEHICLE  EMISSION  AND
      FUEL STANDARDS
      "Sec.  202.  (a)  Except as otherwise provided in sub-
      section (b) —
         "(1)  The Administrator shall  by regulation pres-
         cribe (and from time to time revise) in accordance
Chemistry and Physics Laboratory
                                                   79

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        with the provisions of this section, standards appli-
        cable to the emission of any air pollutant from any
        class or classes of new motor vehicles or new motor
        vehicle  engines, which in his judgment  causes or
        contributes to, or is likely to cause or to contribute
        to, air pollution which endangers the public health
        or welfare . . .
        "(b) (2) Emission standards under  paragraph (1),
        and measurement techniques on which such stan-
        dards are based  (if  not promulgated prior to the
        date of enactment of the Clean Air Amendments of
        1970), shall be prescribed by regulation within 180
        days after such date.
        "(e) In the event a new power source or propulsion
        system for new motor vehicles or new motor vehi-
        cle engines is  submitted for  certification pursuant
        to section 206  (a), the Administrator may postpone
        certification until he has prescribed standards for
        any air pollutants emitted by such vehicle or en-
        gine which cause or contribute to,  or are likely to
        cause  or  contribute to, air  pollution  which en-
        dangers the public health or welfare but for which
        standards  have  not  been prescribed  under  sub-
        section (a)."
   Measurement technology  is  being developed and
evaluated  for  regulated and  non-regulated  emissions
from on-the-road vehicles and advanced power sources.
Improved  optical-measurement instrumentation  has
been developed  for the regulated pollutants. Measure-
ment techniques were developed to support a reactiv-
ity type hydrocarbon standard if undertaken.  Exten-
sive research  has been done on sampling techniques
for  particulate  emissions  from  light-duty vehicles
operated on  leaded  and non-leaded fuels using test
vehicles with and without catalytic devices.
      "REGULATION OF FUELS
      "Sec. 211.  (b) (2) For the purpose of registration of
      fuels and fuel  additives, the  Administrator may also
      require the manufacturer of any fuel or fuel additive—
         "(B) to  furnish the description  of any analytical
         technique that can be used to detect and measure
         any additive in such fuel, the recommended range
         of concentration of such  additive, and the recom-
         mended  purpose-in-use of such additive, and such
         other information as is reasonable and necessary to
         determine the emissions resulting from the use of
         the fuel  or  additive contained in such fuel,  the ef-
         fect of such fuel or additive on the emission control
         performance of any  vehicle  or vehicle engine, or
         the extent to  which such  emissions affect the
         public health or welfare . . .
      Tests under subparagraph (A) shall be  conducted in
      conformity  with test procedures and protocols estab-
      lished by the Administrator. The result of such tests
      shall not be considered confidential.
         "(c) (1)  The Administrator may, from time to time
         on the basis of information obtained under subsec-
         tion (b)  of  this section or other  information avail-
         able to him, by regulation, control or prohibit the
         manufacture, introduction into commerce, offering
         for sale, or sale of any fuel  additive for use in  a
         motor vehicle  or motor vehicle  engine (A) if any
         emission products of such fuel or fuel additive will
         endanger the public health or welfare, or (B) if emis-
         sion products of such fuel or fuel additive will im-
         pair to a significant  degree the performance of any
         emission  control  device or system  which  is  in
         general use, or which  the Administrator finds has
         been developed to a point  where in  a reasonable
         time it would be in general use were such regulation
         to be promulgated.
         "(2)  (C) No fuel or fuel additive may be prohibited
         by the Administrator under paragraph (1) unless he
         finds, and publishes such finding, that in his  judg-
         ment such prohibition  will not cause the use of any
         other fuel or fuel additive which will produce emis-
         sions which will endanger the public health or wel-
         fare to the same or  greater  degree than the use of
         the fuel or fuel additive proposed to be prohibited."
   CPL provides support in development of emission
protocols for fuel additives effects. CPL also performs
the emission characterization of  non-regulated  emis-
sions from  advanced  alternate  power systems.   In
1973 nonregulated emissions from advanced alternate
power  systems were  investigated.    In  1973  con-
siderable work was done on  the problem  of sulfate
formation  by  exhaust  oxidation  catalyst systems.
Work  was  begun  on  alternate  automotive power
systems such as the Wankel engine  and the passenger
vehicle  diesel engine.

      "ADDITIONAL REPORTS TO CONGRESS
      "Sec. 313. Not later than six months after the effective
      date  of this section and not later than January  10 of
      each  calendar year beginning after such  date, the Ad-
      ministrator shall report  to Congress on measures taken
      toward implementing the purpose and  intent of this
      Act including,  but  not limited to, (1) the progress and
      problems associated with  control of automotive ex-
      haust emissions and the research efforts related  there-
      to;  (2)  the development of air  quality criteria and
      recommended  emission control requirements; (3) the
      status of State ambient air standards setting, includ-
      ing such plans  for implementation and enforcement as
      have been developed; (5) the extent  of development
      and expansion of  air pollution monitoring  systems;
      (6) progress and problems related to development of
      new and improved control techniques; (7) the develop-
      ment of quantitative and qualitative  instrumentation
      to monitor emissions and  air quality; (8) standards set
      or under consideration  pursuant to title II of this Act;
      (9)  the status  of State, interstate, and local pollution
      control programs established pursuant to  and assisted
      by this  Act; and (10) the reports and recommendations
      made by the President's Air Quality Advisory Board."
   Technical support is provided by CPL in develop-
ment of  air quality  criteria documents and  progress
reports required  by Congress on air quality, emission
instrumentation, and emission  standards  for  moving
vehicles.
   Table   11 contains a summary  of  resources em-
ployed by CPL  for  Fiscal  Year 1974  in support of
applicable sections of the Clean Air Act.
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                        ANNUAL REPORT 1973

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Table 11. SUMMARY OF RESOURCES FOR CHEM-
ISTRY AND PHYSICS LABORATORY FOR FISCAL
                  YEAR  1974
Section of
Clean Air
Act sup-
ported
103
108
109
110
111
112
202
211
313
Total3


Funds,
$103
536
1587
562
2393
1847
330
636
780
59
8730



Positions
5
22.5
9.1
12.5
17.2
5.1
13 5
5
2.1
92


Approximate
percent
6
18
6
28
21
4
7
9
1
100
aDoes not include SO.5 million of special energy appropria-
tions.
ORGANIZATION

   The Chemistry and Physics Laboratory is organized
into ihree branches. One of these deals with the prob-
lems of the physical and chemical transformations of
pollutants in  the atmosphere, and the other two are
concerned with the development of techniques and
instrumentation for the measurement of air pollution.
All three branches are involved in both laboratory and
field research and implement their programs through
in-house projects and extramural research grants and
contracts.
 Atmospheric Chemistry

 and Physics Branch

   The  program  of the Atmospheric Chemistry and
 and  Physics  Branch involves both  laboratory and
 field  studies.  Laboratory  studies  are conducted  in
 clean glass chambers with  synthetic mixtures and  in
 large irradiation chambers with real mixtures such  as
 motor vehicle exhaust. Hypotheses developed in these
 laboratory studies are tested in the field by analysis  of
 the atmosphere at critical sites chosen on the basis  of
 the pollution sources, meteorology, and topography
 of the area. All of this information is used to choose
 appropriate  air  pollution  strategies as well  as  to
 develop mathematical models of atmospheric photo-
 chemical reactions.  Although the atmospheric chemis-
 try and physics program previously concentrated on
 atmospheric reactions of gaseous pollutants such  as
are involved in the formation of ozone, research now
includes studies of atmospheric  reactions  involving
aerosols. The Branch also conducts research to deter-
mine  the  effects  of environmental  pollutants on
materials. These capabilities in atmospheric chemistry
are  used  in  the  Laboratory's participation  in  the
Regional Air Pollution Study (RAPS) and in the Fuel
and Fuel Additive Registration Program.


Air Quality Measurement

Methods Branch

   The Air Quality Measurement  Methods  Branch
conducts research operations providing EPA with the
capability of assessing environmental quality. This re-
search  is designed  to produce and evaluate new and
improved techniques for the identification and quan-
tification of contaminants in the environment for field
and laboratory use. The Branch develops instruments
for performing continuous or periodic monitoring of
the environment with minimal  human attendance,
and develops  sensor systems for air quality measure-
ment of pollutants in ambient air. Staff personnel
provide methods  for  the  analytical extraction  of
contaminants  from  the  environment  and  for the
qualitative and quantitative analysis of said contami-
nants after transport to the laboratory.


Emission Measurements

Research Branch

   The Emission Measurements Research Branch con-
ducts research and development activities to provide
analytical techniques and instruments for the identifi-
cation and precise measurement of environmental
pollutants  in  emissions discharged from all types of
sources, both mobile and stationary. These activities
are carried out primarily  to support the implementa-
tion of national emission standards for mobile sources,
performance  standards  for  new stationary  sources,
and  national  emission standards for  hazardous air
pollutants as required under the provisions of the
Clean  Air Act of  1970. This Branch  also conducts
studies for the chemical and physical characterization
of pollutants emitted from various sources.
 PHYSICAL FACILITIES

   A research prototype lidar system, designed speci-
 fically  for  particulate emission measurements  from
 stationary sources, is  housed in a mobile van to facili-
 tate field studies now  in progress.
Chemistry and Physics Laboratory
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Pollutant emission patterns from exhaust stacks of stationary sources are simulated using NERC-RTP's wind
tunnel.  Test automobiles are used in developing measurement methods for mobile sources.
   Other research  prototype systems include two re-
 search  infrared  spectrophotometers for  the remoie
 sensing of emissions from  stationary sources. These
 instruments are also  capable  of  long-path  measure-
 ment  of  extended  source emissions.  The Bendix
 spectrophotometer is presently computer-programmed
 to  monitor ozone  in  the  atmosphere.  The Convair
 spectrophotometer has  scanning  capability in the
 3-to-5and 7-to-14 micron wavelength range and much
 higher  resolution  (1.0 cm~1) than the  Bendix (10
 cm-1).
   An experimental stationary source simulator is in-
 stalled in a leased  facility at the Beaunit Corporation
 Technical Center in the Research Triangle Park. This
 facility is used to generate  test flue gases with partic-
 culate matter, moisture, and other pollutants under
 defined conditions—conditions that must be known
 so that sampling and analysis methods can  be evalu-
 ated  under controlled  experimental situations before
 actual field testing is undertaken. This equipment pro-
 vides a 2 by 3 by 35 foot test section, up to 450°F
 (233°C) flue gas temperature, and 80 ft/sec (24m/sec)
 flow  velocities to simulate  conditions encountered in
 typical  power plant operations. Both extractive and
cross-stack optical  instruments are tested at this facil-
ity  before actual installation or field testing at com-
bustion sources.
   The  electron  optical facilities  include scanning
electron  microscopy  (SEM),  transmission  electron
microscopy  (TEM), and X-ray diffraction equipment.
The SEM, used for morphological studies of stationary
and mobile  source particulate emissions, is equipped
with  two X-ray spectrometers that give it a  capa-
bility for quantitative and qualitative chemical analy-
sis as well. The wavelength X-ray spectrometer allows
conversion of the SEM to an electron microprobe for
quantitative chemical analysis of particles smaller than
1  micron in diameter.  The energy dispersive  X-ray
spectrometer allows qualitative chemical analysis, for
elements  beyond  sodium, of  particles only  a few
hundred angstroms in diameter. The TEM is used for
examination of  particles smaller  than  0.1 micron in
diameter where crystal structure is an important con-
sideration. Electron diffraction  techniques  afford  a
means of identifying the  compound  species  of the
particles being examined. X-ray diffraction is used for
identification of  crystalline material   or mixtures.
Quantitative analysis  is possible from  observation of
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                     ANNUAL REPORT 1973

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                                                                                                  .
Atmospheric photochemical  reactions of  pollutants are studied in  NERC-RTP's small  "smog  chamber.'
 intensities of X-ray maxima as a function of percent-
 age composition of a crystalline phase.
   The mobile source emissions laboratory is used for
 the observation  and delineation of the emissions of
 mobile sources, their characterization and quantifica-
 tion,  and the development of the most precise techni-
 ques  for their analysis. The wide range of analytical
 capability  includes particulate and  gaseous compo-
 nents  such as sulfates, fuel  additive  components,
 and   other  nonregulated emissions.    This  general
 capability  is provided by  analytical  facilities  that
 include;

   •  Hitachi RMU-6L mass spectrometer coupled to
      a Perkin-Elmer  990 gas chromatograph.  The
      mass  spectrometer accurately  measures   the
      atomic mass of molecules presented to it while
      the gaschromatograph provides fractionation by
      the principle of  absorption. The  mass spectro-
      meter  can  also  analyze  gaseous  and  liquid
      samples to  provide unique  information on the
      molecular  weights  of the chemical species pre-
      sent.
   •  Gas chromatography capability  for separating
      and analyzing automotive exhaust by its  indi-
      vidual  components.  This  capability typically
     results in over 100 hydrocarbons and many sub-
     stituted organic components, and  is  being ex-
     panded to higher molecular weight components.
     The  principles  involve  selective  absorption,
     elution, and  detection using flame ionization
     detectors that respond with extreme sensitivity
     to individual  carbon atoms. Typical sensitivities
     are about 0.01 ppm.  Special techniques  allow
     these limits to be extended approximately an
     order of magnitude.

   • Other  general  analytical  equipment including
     NMR (Varian T60), infrared spectrophotometer
     (P-E 180), UV-visible spectrophotometers (Gary
     Model 14 and  Beckman  Model B), chemilumi-
     nescent equipment, atomic  absorption, micro-
     balances,  liquid  chromatographs, and  other
     modern analytical laboratory instruments.


   The  mobile  source  testing  facility is installed  at
Beaunit's Technical Center in Research Triangle Park.
Installed equipment  includes a water brake certifica-
tion dynamometer complete with a constant-volume
sampler and a particulate sampling tunnel. Also avail-
able for installation are two engine dynamometers for
light-duty engines and  one  engine  dynamometer for
Chemistry and Physics Laboratory
                                              83

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Elemental analyses of atmospheric aerosols are conducted using X-ray fluorescence techniques.
heavy-duty engines.  Dilution-tunnel  and  constant-
volume samplers are available to allow the measure-
ment of gaseous and particulate emissions. This equip-
ment allows vehicles and engines to be operated under
conditions that simulate  those  encountered  by the
general population.
   These  facilities allow the operation of vehicles and
engines to permit evaluation of control devices (such
as catalysts) and the characterization of non-regulated
emissions caused by unusual operating conditions or
the use of the other fuel components—either fuel addi-
tives or unusual fuels.
   The analysis of  air for pollutants by long-path in-
frared spectroscopy was used  by the early workers in
the field of air pollution to detect ozone as a constit-
uent of smog.  A new system, capable of detecting frac-
tional parts per billion  (by volume)  pollutant  con-
centrations, is operated by  CPL personnel. This  new
long-path  irradiation  chamber has a basic length of
approximately 30 feet; mirrors  on each and provide
an optical path  of over 3000 feet. When this effective
path  length of air  is  analyzed with a Fourier Trans-
form Infrared  Spectrometer and a computer for nearly
instantaneous data analysis, pollutants at  concentra-
tions of a fraction of a part per billion (by volume)
can be identified  and measured. The system  is now
used to detect pollutants that have not been measured
or that have  been measured  only  with  difficulty,
both in the laboratory and field.
   Several mobile  laboratories  are  used  for  field
studies of atmospheric chemistry and physics. These
laboratories are equipped  with  gas chromatographs
and ozone, sulfur dioxide, and NOX analyzers. Aerosol
sampling and sizing equipment is available, as well as
weather monitoring equipment.
   Two smog chambers, soon to be operational, will
permit simulation of polluted atmospheres for study
of aerosol formation and  growth and hydrocarbon/
nitrogen-oxide/oxidant  reactions.  Five chambers are
in use for simulating polluted atmospheres to study
the effect of such atmospheres on critical materials.
MAJOR PROGRAM AREAS

   Principal efforts of personnel of the Chemistry and
Physics Laboratory  are  aimed  in two  directions:
studies of the physical and chemical transformation
of atmospheric pollutants, and development of tech-
niques and instrumentation for measuring air pollu-
tion. The former includes the  interaction of air pollu-
tants with materials and the consequent effects.
Pollutant Transformation

   Among  ongoing studies in the area  of  pollutant
transformation  are  those on   (1)  formation and
removal of noxious gases in the atmosphere, (2) effects
of  aerosol  composition  on visibility,  (3)  oxidant/
precursor relationships for control strategies,  (4) the
Regional Air Pollution Study, relating to air  quality
characterization,  (5)  the character  and  origin  of
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                     ANNUAL REPORT 1973

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aerosols, and  (6) effects of air pollutants  on organic
and inorganic  materials.

   Formation  and Removal of Noxious Gases in the
Atmosphere— Transformations of sulfur oxides, nitro-
gen oxides, and organic pollutants are being identified
and  described quantitatively.  Gas- and condensed-
phase  processes are both  under investigation. Reac-
tivities  and  reaction  paths  are  being established.
Intermediate chemical species  as well as final oxida-
tion products  are being identified and measured. Real
atmospheres are studied  with mobile  equipment  at
selected  locations.  Simulated  polluted  atmospheres
are studied  under controlled conditions in  the labora-
tory.  Results,  being fit into chemical mechanisms, are
yielding  parameters for the mathematical modeling  of
the atmospheric transformation processes. The results
are disseminated  in reports on  the chemical  and
physical  processes  involved  in the formation, trans-
port,  and removal of toxic and noxious substances  in
the atmosphere. Technical papers are published which
provide  insights into the self-cleansing properties  of
the atmosphere. Rate and mechanism  data are pro-
vided for the  mathematical modeling of the reactions
in the polluted air.  Relationships between pollutant
emissions and adverse effects are described. Advice is
given  as  to  control strategies for  minimizing the
formation of noxious gases in the atmosphere. Nearly
all of the nine atmospheric  noxious gas tasks under
way are  multi-year projects which will be  continued.
Three of these tasks are described below.

   Field  Studies of Gaseous Pollutants—The objec-
tives of these  studies are to characterize  the St. Louis
and  Houston  atmospheres. CPL  interest  includes
compositional differences as  well as similarities of air
samples as a function of time of day and sample site
location.  Of  principal  interest is  the  hydrocarbon
distribution, NOX concentration, and oxidant produc-
tion in these two cities. Future work of this type will
involve  vinyl  chloride  and  other halogenated pollu-
tants   in  Houston,  and  oxidant  transport  in  the
Ohio/Indiana area.

   Los Angeles Reactive Pollutant Study—This study,
a cooperative program with the Coordinating Research
Council,  is  now in its data  analysis and  reporting
phase; it may  be concluded next year. An  attempt is
being made to  develop a model  of a  reacting and
moving parcel  of polluted air in the Los Angeles area.
Measurements were  made  on such  pollutants as NO,
N02, 03, CO, and hydrocarbons. Samplers were both
airborne   and   groundbased.  Air  movements  were
tracked with tetroons and radar.

   Halogenated Compounds in  the Atmosphere— This
research   grant  task  at   Rutgers   University   is
concerned with  the measurement, tropospheric reac-
tions, and lifetime of  freons.   In the  past several
years, the  use  of fluorinated hydrocarbons has in-
creased  considerably.   Lovelock's tropospheric mea-
surements show that levels of Freon 11 and  1 2 in the
atmosphere are  increasing  almost proportionately to
the emission  rates. This work will look into possible
removal  processes for  the freons.   If  no  removal
processes  can  be found, then recommendations will
probably  have to be made  on the wisdom of  the
buildup of  non-reactive halocarbons  in the atmos-
phere. Work during the coming year will be expanded
to allow increased field measurements, using a mobile
laboratory.

   Effects of Aerosol Composition on  Visibility—Visi-
bility reduction is the most obvious effect of atmos-
pheric  pollution, but  ironically  it is not well under-
stood.  It  is recognized that  visibility is spoiled by
light scattering from aerosol particles, but the physics
of the  scattering phenomenon and the chemistry of
the formation and growth of the scattering particles
have not been adequately explained. In order to bring
visibility loss under control, further scientific study
of its causes is required.
   The output of the program will include (1) optical
properties of primary and secondary aerosols; (2) rela-
tionships  between visibility  loss and aerosol char-
acteristics  such  as   size,   shape,  and   chemical
composition;  (3)  effects  of relative humidity on
aerosol  properties; (4)  scientific data for  visibility
criteria  and standards;  and (5)  data  from  which to
derive  pollution control strategies that will  improve
atmospheric visibility.

   Determination of Oxidant/Precursor Relationships
for Control Strategies-Ox'\dants are legally controlled
pollutants, but they are not emitted  directly to the
atmosphere.  An  oxidant  is formed  in  the air by
photochemical  reactions involving NOX, oxygen, and
hydrocarbons. The word oxidant designates material
that  causes  an  oxidation  reaction  in  certain  test
procedures.  Oxidant generally consists of about 90
percent ozone and 10 percent peroxyacyl nitrates.
   Control of oxidants follows from control of their
precursors—NOX   and   hydrocarbons.  Permissible
limits of the  precursor concentrations must  therefore
be based on  knowledge of the  photochemical  proc-
esses in the air. The oxidant/precursor relationships
must be determined in quantitative detail.
   The  problem is studied in laboratory simulations
that  yield precise but  indirect determination of the
oxidant/precursor relationships.  Field  studies are also
being carried  out for approximate but direct determi-
nation  of the relationships. From the results of all the
studies, empirical relationships between the chemical
variables are derived.
Chemistry and Physics Laboratory
                                                85

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   Regional Air Pollution Study: Air Quality Charac-
terization—The monitoring network of the RAPS will
measure gaseous pollutant concentrations and meteo-
rological  variables for  use in modeling the transport
of the pollutants in the urban air mass. The network
will have little impact on describing and modeling the
transformations of the pollutants, however, especially
aerosol formation and growth. It has therefore  been
necessary   to  establish this  subprogram  which ad-
dresses atmospheric chemistry problems.
   A  team of  experienced aerosol  scientists was
assembled  in St. Louis  in  the  summer of 1973 to
conduct  an  intensive  aerosol  characterization  pro-
gram. Previous  experience with the California  aerosol
was  the  basis  for  the development of the  aerosol
study. Special  EPA mobile  facilities were used for
aerosol characterization. The results of  the study are
currently   being  analyzed and  developed  for publi-
cation.  Two gaseous  pollutant transformation pro-
jects  have  been under way:  the first is the study of
the transformations of NOX and SOX in power  plant
plumes; the second is laboratory verification of the
kinetic models that are to be applied to the network
data.
   The  program  output  includes:  identification  of
sources of visibility loss in St. Louis; specifications of
particle sizes, size spectra, and chemical composition;
fine-particle  spatial  distribution;  identification  of
gas/particle interactions for  development of visibility
reduction  models; data on choice of tracer substances
for  study of  regional  atmospheres;  and chemical
inputs to the photochemical modeling effort.

   Character and Origin of Aerosols—Physical and
chemical properties of source, ambient, and  natural
aerosols  are being determined.  Aerosol  generation
rates  for  various sources are being established. The
major sinks for aerosol pollutants are being identified
and  the removal  rates are being defined.  The effects
of the aerosols on gas-phase atmospheric chemical
reactions   are  under   investigation,  along with the
gas/particle  conversions  and  the  particle-removal
processes.  The results  of the research are  being used
to establish the contribution of the  various sources to
the ambient atmospheric aerosol loading; characterize
urban, natural, primary source, and secondary source
aerosols; develop quantitative descriptions of  genera-
tion  and  removal  rates associated  with  each major
aerosol source  and  sink; and quantify aerosol effects
on  atmospheric  chemical  reactions.  The scientific
data  are basic to the  promulgation  of fine-particle
criteria  and  standards and  to  the development of
effective control procedures.

   Relating Fine-Particle  Aerosols  to   Sources-The
pollution aerosol  is  a dynamic system whose physical
and chemical characteristics depend  in a complex way
On-the-scene research into atmospheric  aerosol be-
havior is performed using NERC-RTP's mobile labo-
ratory.


on  the background aerosol and  on particle and gas
emissions.  The  goal  of  this  research  is  to develop
experimental and theoretical methods for relating the
properties of the pollution aerosol  to the characteris-
tics of emission sources.  This is being accomplished
by  (1) beginning with the observed characteristics of
the  pollution  aerosol   and  formulating  a  set  of
hypotheses  relating the  aerosol to  the sources of
particles and  gases;  (2) carrying  out laboratory
experiments  and  theoretical  calculations  aimed at
testing these mechanisms; and (3) arriving at a tested
quantitative understanding of the origins of the smog
aerosol. Experimental studies include  investigations
of  the conversion  of  organic  gases  and  SC>2  to
particulate matter in an ozone-rich atmosphere.

   Air Pollutant Effects on  Organic and  Inorganic
Materials— The  interaction of  gaseous and particulate
pollutants  with material  surfaces is  of vital  interest
from  two points of view: (1)  the damage inflicted on
man-made  materials by  acidic vapors, soot,  and other
airborne matter is of concern, and (2)  the uptake of
pollutants by the surfaces is a  major removal path and
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                      ANNUAL REPORT 1973

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must be understood quantitavely for development of
atmospheric models and control plans.
   Statistically designed, controlled-environment lab-
oratory  experiments   are  being  used  to  establish
cause/effect   relationships  between  pollutants  and
materials.  Laboratory  experiments  with S02, NO2,
and  03 are being carried out on an intramural basis.
The  results of these  studies will include reports and
documents on the direct and synergistic effects of air
pollutants  on nine classes of sensitive, economically
important  materials,  Final reports will  contain dose/
response  data,  at pollution  levels  below  primary
standards,  that may  be  used  to  set  secondary  air
quality standards. Quantitative data will be generated
on  the rates  of  uptake of  individual  pollutants  by
surfaces of various types.
   In the materials-damage  survey, an evolved, two
level, fractional,  factorial experiment has been con-
ducted,  using controlled-environment  chambers, to
screen and  assess the  damaging effects,  both direct
and  synergistic,  of  SC>2,  NC>2, 03,  and  climatic
parameters  on steel,  galvanized  aluminum,  tires,
paints,  plastics, fabrics and dyes,  marble, and con-
crete.
   Based on  the results of this experiment, a  more
definitive orthogonal-square, controlled-environment
experiment will  be designed and  conducted during
the  coming year to produce dose/response  relation-
ships  for  materials  found  to  be  sensitive to  air
pollution, both directly and synergistically.
   Two  additional programs will be  undertaken in
1974.  The first  will  be a  multi-year field study of
pollutant effects on materials,  to be conducted in  St.
Louis with the assistance  of Rockwell personnel who
are  contractors  for  the  RAPS. Materials  will  be
exposed at selected locations  and examined periodi-
cally for damage. An effort will be made to correlate
observed damage with measured pollution levels. The
second  new undertaking will be a laboratory investi-
gation of the  uptake of pollutants by various types of
materials.
Pollutant Measurement

   Work relating to air pollution measurement, the sec-
ond of CPL's two major functional work areas (the first
is pollutant transformation studies), includes (1) new
and improved  methods  for measuring  and  analy-
zing ambient  air particulates,  (2) personal exposure
dosimeters, (3) fine particulate methodology, (4) the
RAP's gaseous pollutants in  ambient air,  (5) mobile
source emissions, (6) gaseous pollutants emitted from
stationary sources, (7) criteria for selection of station-
ary source  measurement  strategies  or  methodology
and instrumentation, and  (8) particulates and hazard-
ous  substances emitted  from  stationary  sources.
   Ambient Air Paniculate Measurement and Analy-
sis Methods —The  aim of  this  project  is to provide
EPA  with  the capability  for measuring parameters
judged to be relevant to  pollution of the atmosphere
by suspended particles. Parameters of present concern
include  mass,   particle-size  distribution,  elemental
composition, and visibility  attenuation.
   Considerable progress  has  been made  in the design
of collectors capable of  segregating particles in two
sizes  regimes (0 to 3.5 and 3.5 to 20 microns) on a
Teflon surface. Exposed filters are examined for mass
determination  by  Beta-ray attenuation,  and for ele-
mental  composition by  X-ray  fluorescence.  Filters,
filter  holders,  filter transport mechanisms, and identi-
fication coding and decoding devices have been or are
being designed for total  compatibility, resulting in a
system  geared  to  the handling  of large numbers of
samples with minimum opportunity for human error.
   A  major step forward  was the development of a
simple, sensitive,  and  reasonably  specific device for
the automated  collection  and  quantification of sul-
furic  acid mist.  Early evaluation is planned. A similar
device capable  of  measuring particulate nitrate is also
being developed.
   The  X-ray  fluorescence technique  for  measure-
ment of trace elements in  airborne particles has been
notably  improved  through  updated computer pro-
gramming that eliminates  inaccuracies previously  in-
curred as a result of variations in particle  size.
   Future efforts  will  include further improvements
in collection, sizing and  analyzing techniques, and
development of objective methods of assessing visibil-
ity reduction.
   Important progress  was  made toward development
of a  rapid method  for the  measurement  of benzo-
(a)pyrene,  an  important  carcinogenic  component  of
pollutant particles.

      Personal  Exposure Dosimeters— This  program,
new in 1973, is aimed at providing simple devices that
will  record  the exposure  of individuals to  specific
pollutants,  independently  of  movements  of  those
individuals  within and  between  areas  of  differing
pollutant levels.
   A  major  initial  contract-procurement   effort   is
directed toward  preparation  of  a state-of-the-art
survey to identify  available measurement techniques,
to clarify uncertainties in  informational needs  (e.g.,
time  resolution, sensitivity,  and  precision) and  to
assess  the  degree  to  which it may  be reasonably
assumed that existing miniaturization techniques can
be  applied  to  the  several candidate  measurement
methods. Concurrently, procurement is being sought
for a  small number of prototype sensors for pilot use
and evaluation. Such  pilot  use will aid in establishing
realistic design criteria for  future  prototype  procure-
ments.
Chemistry and Physics  Laboratory
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   Fine-Paniculate  Methodology—The objective  of
this program is to develop a simple,  low-cost,  2- or
3-stage  device  that  will  effect  the dichotomous
collection of respirable and  non-respirable  particles
from  ambient  air  in a  manner compatible  with
subsequent  assessment of  their mass and chemical
composition.
   During 1973,  laboratory and  preliminary design
work  led to initiation of  a  procurement  for the
fabrication  of  prototype 2-stage  collection  devices
that will be fieldworthy yet amenable to production
at moderate ($2,000) cost. Design criteria include an
intake section  whose performance will not be seri-
ously  affected  by wind direction or speeds of  up to
15km/hr.
   Future activity will include field evaluation of the
product  of  the  procurement described  above and
fabrication  of   improved  second-generation  proto-
types. Every effort  will  be  made  to provide the
capability  of   real-time  assessment  of fine-particle
burden in the final product. A corollary activity  is the
development of reliable  methods   for  generating
monodisperse  aerosols of  precisely known particle
size for use in  the  calibration of sizing instrumenta-
tion.
   A gas-chromatographic instrument capable of meas-
uring acetylene  at  levels  of  0.1 ppb was fabricated
under contract. This capability will be used in studies
applying acetylene as an  intrinsic tracer  substance
indicative of automotive traffic.
   Further work in this task will  consist  largely of
field trials and  applications  of  the techniques des-
cribed above.

   Instruments for Measuring Gaseous Pollutants in
Ambient Air—Jhe objective of this program is to pro-
vide EPA  with  both instrumental and laboratory
methods for the measurement of important gaseous
pollutants such as ozone,  NOX, SOX, CO, and hydro-
carbons. Its aims are: to provide measurement capa-
bility for a specific pollutant where a need is known
to  exist;  to  improve that  capability to an  EPA-
acceptable  level of reliability; to  simplify the hard-
ware resulting from initial efforts to a degree permit-
ting routine operation of the method or instrument by
personnel available to enforcement agencies; and to
seek design optima (or alternate methods/instruments)
that will facilitate proliferation at costs commensurate
with EPA resources.
   RAPS  Measurements and Instrumentation—The
objective of this program is to provide measurement
capabilities necessary to complete the Regional Air
Pollution Study. The major accomplishment in  1973
was  the  awarding of a contract for activation and
operation of Regional Air Monitoring System (RAMS)
to Rockwell International.
   An  X-ray flourescence  analyzer  was fabricated,
providing RAPS with the capability of analyzing col-
lected  particulate  samples for  up to 30  elements.
Sensitivity  and analysis time are sufficient  to handle
large numbers of samples collected over periods of 2
hours or more.
   Twelve  automated  dichotomous  samplers  were
fabricated to collect particulate  samples, segregating
respirable from non-respirable fractions. A Beta-gauge
was developed to assess the mass of particles in each
fraction  collected. This gauge will be fabricated to
handle the same samples collected for X-ray analysis.
   Two separate,  laser-powered, long-path spectro-
photometers  were developed for  use in  RAPS for
determining gaseous  pollutant burdens, averaged over
line-of-sight paths  of up to 1 kilometer.  Results will
be utilized in improving pollution-transport modeling
capability. These instruments  are  capable of analyzing
for CO, 03, SO2, and other pollutants.
   A contract was let for fabrication of a fluorescence
instrument for measuring N02- This, a direct measure-
ment,  will assist  in confirming data generated  by
chemiluminescence (indirect)  instruments in RAMS.
Atmospheric particulate  matter  is  analyzed using
liquid chromatography.
                                                                            ANNUAL  REPORT 1973

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Benzofajpyrene in atmospheric paniculate matter is measured using a CPL-developed instrument
Mobile Source Emissions

   Activities encompassed in  this task include  the
definition, description, and measurement of emissions
from  all  mobile sources. Possible emissions are in-
vestigated and  techniques for  their measurement are
developed. The operational parameters of this  meas-
urement are  defined so that the critical  health-related
questions  can  be investigated. Physical and kinetic
considerations   are  addressed  in  order to  define
practical  limits of consideration. Emphasis is on cur-
rently  nonregulated emissions that might have  the
greatest impact on our environment. Techniques for
the measurement of regulated  emissions are continu-
ally reviewed to ensure their efficacy.
   In the past year, methodology has been delineated
to routinely  perform analyses  of hydrocarbons, non-
reactive hydrocarbons,  and diesel odors. Methodology
is being developed to  assess sulfate emissions and to
measure SO2 in exhaust.
   Major efforts have been expended to define partic-
ulate  emissions and the  technology  for measuring
them. This work has led to the measurement of partic-
ulates from  a wide variety  of  light-duty  vehicles,
including vehicles operated  on  nonstandard fuels,
with and without catalysts,  and  with and without
other novel  control  systems.  Projects are currently
under way to extend these techniques to heavy-duty
vehicles  and other mobile sources.


Gaseous Pollutants Emitted

from  Stationary Sources

   The objectives of this project are to develop and
evaluate  measurement  techniques  and  monitoring
systems  for gaseous  emissions in support of control
regulations for selected industrial sources. The research
and development program consists of one or more of
the following  efforts to  meet the  required needs:
Chemistry and Physics Laboratory
                                             89

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establish the state-of-the-art, conduct feasibility stud-
ies  of new or  improved concepts  and  evaluate their
application to  specific gas pollutants,  develop and
evaluate  field prototypes, and evaluate commercially
available prototype systems. Methods  and measure-
ment systems  include improved  manual  methods,
in-stack  instrumentation,  and  remote sensors for
sulfur-containing compounds,  NOX,  halides, CO, hy-
drocarbons, and odorous  materials.  Also involved  is
the development of supporting technology including
both flow and  temperature measurements as well as
sample-conditioning mechanisms.

   Selection of Criteria for Stationary-Source Measure-
ment Strategies--The objectives of this  activity are to
develop performance criteria for prescribed methods
and monitoring systems and to establish test proce-
dures by which criteria can be verified. These criteria
and procedures provide the technical data to support
the prescribed methods and monitoring requirements
and to assess the capability  and accuracy of equivalent
or alternate measurement methods.
   Compliance  test methods for NOX and S02 were
evaluated at coal-burning  power plants; monitoring
systems for these pollutants were tested under field
operating conditions. A technical document was com-
pleted  on performance specifications and test proce-
dures for monitoring  systems for  NOX, SC>2, and
visible emissions from Group I stationary sources.


Particulates from Stationary

Sources

   The objective of this project is to develop and eval-
uate measurement techniques and monitoring systems
in  support  of  regulations  for selected  industrial
sources. The research and development program con-
sists of one or more of the following efforts to meet
the required needs, establish the state-of-the-art, con-
duct feasibility studies of new or improved concepts
and  evaluate  their  application  to  specific particle
parameters,  develop  and evaluate field  prototypes,
and  evaluate commercially  available prototype sys-
tems.
Hazardous Substances Emitted

from Stationary Sources

   The first group of substances designated for national
emission  standards for hazardous air  pollutants in-
cludes  asbestos,  beryllium, and mercury.  Future
designations may  include  such  materials as  toxic
metals  (Pb,  Cd, V, Ni, Co, Cr, Mn, As, and Se) or
groups  of polycyclic organic matter (POM). The pur-
pose of this work is to develop measurement methods
to obtain reliable emission data and to support emis-
sion standards for these substances. The program con-
sists of one or  more of the following  approaches to
achieve a working method or system:  feasibility study
of new concepts and their evaluation for specific pol-
lutants, development  and evaluation  of  a  research
prototype, development and evaluation of a field pro-
totype, and  evaluation  of commercial  prototype
systems.
90
                                                                         ANNUAL REPORT 1973

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       Quality
    Assurance
          and
Environmental
   Monitoring
   Laboratory

-------

-------
  Quality  Assurance
and  Environmental
                Monitoring
                Laboratory
QUALITY ASSURANCE
AND ENVIRONMENTAL
MONITORING LABORATORY

^•i
t^m
^^
I^H

METHODS STANDARDIZATION
AND PERFORMANCE EVALUATION
BRANCH

ANALYTICAL CHEMISTRY
BRANCH

ENVIRONMENTAL MONITORING
BRANCH

QUALITY ASSURANCE STAFF

STATISTICAL SERVICES STAFF
Studies  to determine  the  chemical  and physical
composition of fuel additives are conducted  by the
Quality  Assurance  and  Environmental  Monitoring
Laboratory. Research techniques include the analysis
of gasoline for  lead  using an  atomic absorption
spectrophotometer
OVERVIEW OF QAEML'S

MISSION

   The mission of the Quality Assurance and  Envi-
ronmental  Monitoring  Laboratory  (QAEML)  is to
obtain  the data needed to reach and support deci-
sions concerning environmental  quality, particularly
in  the air medium.  Such data are needed in a variety
of activities such  as air quality management, criteria
development,  standards setting, compliance and en-
forcement, emergency  episode control, and source
emission control strategy.
   In  carrying out its  mission, QAEML provides
monitoring services that range from  the first steps of
any monitoring effort—selecting field sites for moni-
toring and making  measurements on  such sites—to
the final  steps of  data evaluation, summarization,
and dissemination.  Quality assurance is  practiced to
control and document the quality  of  the data ob-
tained. Although the use of standardized methods is
an important aspect of quality assurance, such meth-
ods are not always available.
   To supplement the use  of standardized methods,
QAEML maintains expertise in analytical chemistry,
instrument electronics, and statistics to ensure that
method development and  evaluation, formal testing
(including collaborative testing in the community of
users),  and  quality  control procedure  development
can be carried out effectively.  Quality  control pro-
cedures are  formalized  and  disseminated for use
within  EPA,  by the states, and by  other  interested
groups.
   Data evaluation and summarization of information
routinely  obtained in  the  environment and of infor-
mation about analytical methods are provided for the
community of users by appropriate statistical analy-
ses and summaries. Data are entered  into the National
Aerometric Data Bank or  are published through ap-
propriate channels.
                                                    LEGISLATIVE MANDATE

                                                      The mission of QAEML responds to eight sections
                                                    of the Clean Air  Act (103, 108, 110, 111, 112, 113,
                                                    211, and 313). The various sections are shown below
                                                    with  brief  descriptions of the types  of supportive
                                                    activities.
   "RESEARCH,  INVESTIGATION,  TRAINING, AND
   OTHER ACTIVITIES
   "Sec.  103.   (a) The Administrator shall  establish a
     national research and development program  for the
     prevention and control of air pollution and as part of
     such program shall—"(1) conduct and promote the
     coordination and acceleration of, research, investiga-
     tions, experiments, training, demonstrations, surveys.
Quality Assurance and Environmental Monitoring Laboratory
                                            93

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      and studies relating to the causes, effects, extent, pre-
      vention, and control of air pollution;...  (3) conduct
      investigations and research and make surveys concern-
      ing any specific  problem of air pollution in coopera-
      tion with any air pollution control agency with a view
      to recommending a solution of such problem, if he is
      requested to do  so by such agency or if, in his judg-
      ment, such problem  may affect  any  community or
      communities in a State other than that in which the
      source of the matter causing or  contributing to the
      pollution is located;. . .
         "(b)  In carrying out the provisions of the preced-
      ing subsection the Administrator is authorized to—
      "(1)  collect and make available, through publications
      and other appropriate means, the  results of and other
      information, including appropriate recommendations
      by him in connection therewith, pertaining to such
      research and other  activities; . . . ."

   QAEML responds to  Section 103 by evaluating,
testing, and standardizing methods. Quality control
procedures for relevant  methods are also developed.
Material samples  involved in lawsuits are carefully
handled to  maintain chain-oi'-custody requirements
and are sealed  in locked storage cabinets  (inset).
Surveys and  investigations  are  undertaken, both  of
the  general  extent of  air  pollution and  of specific
problems. The voluminous data that result are appro-
priately summarized, analyzed, and disseminated.

   "AIR QUALITY  CRITERIA  AND  CONTROL  TECH-
   NIQUES
   "Sec. 108.    (a) (2)  The  Administrator shall issue  air
      quality criteria for an air pollutant within  12 months
      after he has included  such pollutant in a list  under
      paragraph  (1).  Air quality  criteria for an air pollutant
      shall accurately reflect the  latest scientific knowledge
      useful in indicating the kind and extent  of all identi-
      fiable effects on public health or welfare which may
      be expected from the presence of such  pollutant in
      the ambient air, in varying  quantities . . .
         "(c!  The Administrator shall from time to time
      review, and, as appropriate, modify and reissue any
      criteria or information  on  control techniques  issued
      pursuant to this section

   QAEML responds to  this  section  of the law by
standing ready to evaluate methodology used to ob-
tain  scientific  information  or to undertake surveys
to obtain information  needed  by those  who  must
develop criteria documents.

   "IMPLEMENTATION PLANS
   "Sec. 110.   (a) (1)  Each  State shall,  after  reasonable
      notice and public hearings, adopt and submit to the
      Administrator,  within nine  months after the promul-
      gation of  a national  primary ambient  air quality
      standard (or any  revision thereof) under section 109
      for any air pollutant, a plan which provides for imple-
      mentation, maintenance, and enforcement of  such
      primary  standard in each air quality control region.
      (or portion thereof) within such State.  In addition,
      such State shall adopt  and submit  to the Adminis-
      trator ... a plan which  provides for the  implementa-
      tion, maintenance, and  enforcement  of such second-
      ary standard . . .
      "(2)  . . . The Administrator shall approve such plan . . .
      if he determines that it was adopted after reasonable
      notice and hearing and that—. . .  (C) it includes pro-
      vision for ... appropriate devices, methods, systems,
      and procedures necessary to (i) monitor, compile, and
      analyze data on ambient air  quality

   This section of the law  is supported by QAEML's
activities  in  the evaluation and  standardization  of
methods  for  the criteria  pollutants and in the devel-
opment and dissemination of quality  control proce-
dures  for  standardized methods.   Use of  the  stand-
ardized methods with quality assurance documenta-
tion  provides  the  ability  to  meaningfully compare
data  collected routinely  by  many  unrelated  State
agencies.


   "STANDARDS OF PERFORMANCE  FOR  NEW STA-
   TIONARY SOURCES
   "Sec. 111.   (b) (a) (B) . . . the Administrator shall pro-
      pose regulations, establishing Federal standards of per-
      formance for new sources .  . .
94
                       ANNUAL REPORT 1973

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        "(c)  (1) ..  If the Administrator finds the State
     procedure is adequate, he shall delegate to such State
     any authority he has under this Act to implement and
     enforce such standards . . . ."

   This  requirement is analogous to that of Section
110 of  the Act;  QAEML  supports this section simi-
larly.

   "NATIONAL  EMISSION STANDARDS FOR HAZARD
   OUS AIR POLLUTANTS
   "Sec. 112.  (b) (1) (B)  ..the  Administrator shall pre-
     scribe an  emission  standard for  such  (hazardous)
     pollutant .  . .
        (d)  (1)...lf the Administrator finds the State
     procedure is adequate, he shall delegate to such State
     any authority he has under this Act to implement and
     enforce such standards . . . ."


   This  requirement is  similar  to those of Sections
110 and 111 of  the Act.  QAEML's support is also
in terms of methods standardization, evaluation, and
quality  control procedure development.  Some tech-
nical  assistance is  also  rendered to obtain  data to
assist  the  Administrator in making judgments as to
what constitutes a hazardous pollutant.

   "FEDERAL ENFORCEMENT
   "Sec. 113.  (a) (1)  Whenever, on the basis of any informa-
     tion available to him, the Administrator finds that any
     person is in violation of any requirement of an applica-
     ble implementation  plan . . . the Administrator may
     issue an order requiring such person to comply with
     the requirements of such plan or he may bring a civil
     action . . ."

   QAEML maintains a limited rapid-response capabil-
ity to assist in the collection of data for purposes of
Federal enforcement.

   "REGULATION OF FUELS
   "Sec. 211.  (a) The Administrator may  by  regulation
     designate any fuel or fuel additive and, ... no manu-
     facturer or processor of any such fuel or additive may
     sell, offer for sale, or introduce into commerce such
     fuel or additive . . ."

   QAEML's support of the law consists of the de-
velopment  and  evaluation  of  methods of analyses
and of  the collection and analysis of fuel samples as
required.

   "ADDITIONAL REPORTS TO CONGRESS
   "Sec. 313 ... the Administrator shall report to the Con-
     gress on measures taken toward  implementing the
     purpose and intent of this Act . . ."

   When the inclusion  of  data or method develop-
ments  developed by  QAEML  is  relevant,  the  infor-
mation  is  provided  to support  this provision of the
Act.
Table 12. SUMMARY OF RESOURCES FOR QUAL-
ITY ASSURANCE AND ENVIRONMENTAL MONI-
TORING LABORATORY  FOR FISCAL YEAR  1974
Section of
Clean Air
Act sup-
ported
103
108
110
111
112
113
211
313
Total


Funds,
$103
833
90
1182
405
274
103
225
112
3224



Positions
28
3
14
10
8
3
1
6
73


Approximate
percent
26
3
37
13
8
3
7
3
100
ORGANIZATION

   The Quality Assurance and  Environmental Moni-
toring Laboratory conducts its activities through four
technically oriented branches and a statistical group,
all  of  which  report  directly  to the Office of the
Director.  All activities are coordinated through the
Office of the Director, which also serves as the inter-
face with other EPA units for which QAEML pro-
vides technical support. Table 12 shows the percent-
ages of funds  and personnel  used by QAEML  in
Fiscal Year  1974 to support various  sections of the
Clean Air Act.
Quality Control Branch

   The Quality Control Branch (QCB) provides guid-
ance on development and implementation of quality
assurance  programs to NERC-RTP laboratories, EPA
Regional Offices, and State and local laboratories to
ensure that all aerometric data used in the various
decision-making processes are valid and comparable.
The  Branch develops standard reference samples and
delivery systems for use  in quality control  and cer-
tification programs.
Methods Standardization Branch

   The  Methods Standardization Branch  (MSB)  de-
velops and conducts a methods standardization  pro-
gram   involving   laboratory  evaluation,  procedure
revision, and  collaborative testing.  The end products
are standard analytical methods  for the measurement
of pollutant concentrations in ambient air and those
emitted from sources.  The Branch develops standard
Quality Assurance and Environmental Monitoring Laboratory
                                               95

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reference materials for methods standardization and
calibration.


Environmental Monitoring

Branch

   The Environmental Monitoring Branch (EMB)  is
responsible for the installation, calibration, operation,
and maintenance of special multipurpose pollutant
monitoring stations and  networks such as the tur-
bidity, precipitation, and membrane-filter particulate
networks, and for providing guidance to other govern-
mental agencies  in the design and operation of moni-
toring stations and networks.  The Branch provides
specialized field  monitoring support (including activi-
ties during emergency episodes) to the Office of Air
Quality  Planning and Standards,  the  Office of En-
forcement and  General  Counsel  (OEGC), and the
Regional Offices.  It is also responsible for the deter-
mination of equivalency of candidate methods and
instruments for  published reference methods, and for
the in-house  and field evaluation of commercially
available environmental  monitoring  instrumentation.
Analysis of phosphorus in gasoline is included in fuel
tests conducted at NERC-R TP.
Analytical Chemistry Branch

   The Analytical Chemistry Branch (ACB) provides
analytical  capability to NERC-RTP for the measure-
ment of trace elements and other pollutants present
in various environmental, bioenvironmental, source,
and fuel samples. The Branch provides technical sup-
port and specialized training to EPA Regional, State,
and local laboratory personnel. As required, the ACB
develops  new methods,  modifies  existing methods,
and provides analytical services in support of ongoing
studies including  research  monitoring.  The Branch
is also responsible for maintaining liaison with and
giving technical assistance to the Office of Air Quality
Planning and  Standards with respect  to source sam-
pling  and  analysis methodology  for  trace  elements
and other pollutants to provide valid data for  de-
velopment of source performance  standards.  ACB
personnel  provide analytical  laboratory  services  to
OAQPS, OEGC, or other  EPA programs for  short-
term and special environmental studies in support of
trend monitoring  in such areas as State Implementa-
tion Plans and enforcement actions.
                                                    Statistical Services Staff

                                                       The Statistical Services Staff (SSS) provides statis-
                                                    tical  competence to QAEML by participating in the
                                                    statistical design, execution,  and  analysis of quality
                                                    assurance, methods standardization, and monitoring
                                                    studies.  Personnel carry out mathematical and statis-
                                                    tical  evaluation and report  on internally  generated
                                                    data.  The Staff is a focal point  within NERC-RTP
                                                    for handling, processing,  and  reporting aerometric
                                                    data  received from  the World Health Organization
                                                    and the World  Meteorological Organization.
PHYSICAL FACILITIES

   QAEML personnel are housed at NERC-RTP,  in
Monsanto's Research  Building (located at RTP), and
in  the  Durham Air Monitoring and Demonstration
Facility (DAMDF).  The  Laboratory either owns  or
has access to a  number of special  instruments and
facilities to support its mission.
   The Durham  Air Monitoring and Demonstration
Facility is a specially designed and equipped multi-
purpose facility utilized for the following functions:

   • To demonstrate  advanced  air monitoring
     techniques.
   • To test and  field-evaluate commercially avail-
     able ambient  air monitors, calibration tech-
     niques, and data acquisition systems.
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                    ANNUAL REPORT 1973

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  • To gather pollutant concentration data  gener-
     ated from  special intermethod comparability
     studies.
  • To provide capability for methods and  instru-
     ment equivalency testing.
  • To provide on-the-job-training.

   For special field studies, vans are available to carry
calibration and maintenance equipment  or to be con-
verted  on short notice into air monitoring  stations.
For projects requiring more elaborate air monitoring
equipment,  mobile  laboratories are utilized which,
when  fully  equipped, are able to monitor for the
criteria  pollutants  and common meteorological pa-
rameters.
   Laboratory  facilities used for the analysis of am-
bient, source, fuel, and fuel additive samples by opti-
mized  procedures  include specialized  space that
allows  analysis of fuels and fuel additives under safe
conditions.
   The  analysis  of  samples  by  neutron-activation
techniques is made possible by use of facilities leased
from North  Carolina State  University.  The Univer-
sity's  pulstar reactor is used  (under control  agree-
ment)  to  irradiate  the  samples, which  are later
counted  with  QAEML-owned  equipment located in
the rented space.
   The  25-channel,  direct-reading optical  emission
spectrometer has  been optimized  for the determina-
tion of trace elements in particulate matter. A spark-
source mass spectrometer that can be used to measure
small  concentrations of trace  elements  of possible
health significance is being activated to permit analy-
sis of environmental samples of interest and to com-
plement the neutron-activation  capability.
   Development  of an  Automated  Laboratory Data
Analysis System, nearing completion, will allow rapid
output of validated laboratory  analyses—a capability
not now possible.
MAJOR PROGRAM  AREAS

Methods Standardization

   Methods standardization, which directly supports
Sections  103,  110,  111,  and 112 of the Clean Air
Act, is an important component of the quality assur-
ance system necessary  to generate  valid data.  The
standardization  process is being applied to all refer-
ence methods  given  in regulations  for primary and
secondary national  ambient air quality  standards.
QAEML  is also attempting to standardize some of
the methods specified  in  regulations for new  sta-
tionary sources and for two of  the hazardous pollut-
ants designated  thus far—beryllium  and  mercury.
Evaluations by the standardization process are being
Fuel additive samples are carefully catalogued prior to analysis and registration.

Quality Assurance and Environmental Monitoring Laboratory
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carried out for some  methods not specified in regu-
lations, and  the laboratory is also investigating new
techniques for  the evaluation of  air pollution meas-
urement methods.
   Measurement methods are standardized  in a two-
step process.  First, the candidate method is examined
in  depth in  a  single  laboratory  for the purpose of
identifying and correcting errors,  omissions, ambigui-
ties, and other inadequacies.  Second, the candidate
method is  examined  in several  laboratories  by  an
interlaboratory collaborative test  in which  each par-
ticipant uses the method to measure pollutants con-
tained  in a reference  material.  In this way, the pre-
cision and accuracy of the method are measured, and
the capabilities of the method in the hands of typical
users are estimated.
   The levels of ambient air  quality for each  of the
criteria  pollutants  must be measured by the appro-
priate reference method  (those that were previously
discussed  with regard to standardization  or  by  an
equivalent method).  In 1972, a project was initiated
to  establish  definitive requirements and test  proce-
dures to determine whether methods of sampling and
analyzing  the ambient air may be designated "equiv-
alent methods."    During  this   project, continued
through  1973, performance  specifications  and test
procedures were developed for three pollutants, car-
bon monoxide, ozone, and sulfur dioxide.  The pro-
cedures were tested thoroughly both in-house and  by
an  independent contractor for workability and tech-
nical adequacy.
   In 1973,  numerous  achievements were accom-
plished  in methods standardization.  The following
specific reference materials, required before any col-
laborative testing of a method (part of the standardi-
zation process)  can begin, were developed:

   • A significant portion of the work to develop a
     reference material  for ambient N02  measure-
     ments  was completed.
   • Ozone reference materials were supplied to par-
     ticipants  in the  collaborative  test  of the refer-
     ence method to  measure ambient ozone.
   • Beryllium reference materials  were supplied to
     participants  in  the  collaborative  test  of the
     regulatory method  to measure beryllium emis-
     sions.
   • The Federal  reference  method  for   ambient
     N02  was  withdrawn during  1973.   QAEML
     assisted in the search for an  evaluation of a new
     method.  In partial response to these  needs,
     single-laboratory  evaluations  of  the sodium
     arsenite procedure, the  TGS-ANSA procedure,
     and a significant portion of the triethanolamine
     procedure for ambient  IM02  were completed,
     and  a substantial portion of the work  required
     to collaboratively  test the sodium  arsenite and
      TGS-ANSA procedures for ambient N02 was
      accomplished.
   •  The  collaborative  test  of the chemilumines-
      cence reference  method  for  ozone  was com-
      pleted.
   •  The collaborative test of the 24-hour version of
      the reference  method for measuring ambient
      S02 was finished.
   •  The collaborative test, in a power plant and in
      a nitric acid plant, of the regulatory method for
      measuring NOX  emissions was finished.  This
      method  was found  to be  reliable.
   •  The  collaborative  testing of  the  regulatory
      method  for measuring S02 emissions was com-
      pleted in a power plant and found reliable.  A
      significant portion  of the  collaborative testing,
      in a sulfuric acid plant, was also finished.
   •  A significant portion  of the collaborative  test-
      ing, in a power plant, municipal  incinerator,
      and cement plant, of the  regulatory method to
      measure particulate emissions was completed.
   •  A significant portion  of the evaluation and col-
      laborative testing of the method that measures
      CO,  C02, and  02  in source emissions  was
      completed.
   •  A  portion  of  the  collaborative  test  of the
      method  to  determine visual  opacity was fin-
      ished.
   •  The field portion of the collaborative test, in a
      ceramic  plant,  of  the regulatory  method  to
      measure  beryllium emissions was finished.
   •  A new technique based on the ganged-probe
      concept  was applied  to the evaluation  of the
      method  for  measuring  particulate  emissions
      from stationary sources.  This was found to  be
      a  useful  technique  with  potential  for wide
      application.
   •  A program  was  initiated  to evaluate the  pro-
      posed  method  to measure H2S emissions from
      refineries.
   •  Test procedures for the determination of equiv-
      alent  ambient  air  monitoring  methods were
      developed  and  tested.  The  procedures were
      published as  Proposed "Ambient Air Monitor-
      ing Equivalent and Reference Methods," Fed-
      eral Register,  Vol.  38, No.  197,  October  12,
      1973.  Comments were considered, and  appro-
      priate  changes were made to the proposed regu-
      lations.   The  regulations are currently being
      considered for  final promulgation.

   Plans  for future  methods standardization  follow
the same general direction as in  the past, but involve
new methods.
   Programs for single-laboratory evaluations of  at
least two ambient sulfate methods, and for collabora-
tive testing  of at least one of these, are being devel-
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oped.  The collaborative testing should be completed
in  late  1975.   In 1975 the standardization  process
for methods to measure benzo(a)pyrene  will begin.
   Completion of the standardization of the reference
method for measuring photochemical oxidants (cor
rected for  interferences due  to  SO2 and N09) and
the beryllium and mercury methods is planned.
   The  single-laboratory evaluation of  the reference
method for measuring hydrocarbons should be com
pleted and  a decision reached with respect to the
methods suitable  for standardization.
   Completion  of the collaborative testing  of the
method for measuring S02 and acid mist emissions
from sulfuric acid plants is planned as is further eval-
uation of the method for measuring particulate emis-
sions.   This is  a  very difficult area and  will  require
examination of the  method  at  a  variety of  sources
subject to regulations.
   Evaluation and collaborative testing of the regula-
tory methods for measuring CO, S02, and acid mists
from smelters;  particulate  matter  from asphalt con-
crete plants; particulate  matter  and lead from lead
smelters; fluoride emissions from aluminum reduction
plants and  phosphate fertilizer plants;  total reduced
sulfur from Kraft pulp mills;  and hydrocarbons from
fuel conversion  units are planned.
   New methods  for measuring  NOX  and S02  emis-
sions from  stationary sources will  be evaluated  if
possible.
   Future work in the area of equivalency determina-
tions will  involve the implementation of the regula-
tion requirements, such as reviewing applications for
equivalency  determinations, testing  new and exist-
ing air monitors  to  determine  if they meet  the re-
quirements of  the  regulations, publishing  a  list of
acceptable  "equivalent"  methods,  and  developing
regulations for  NO2 and nonmethane hydrocarbon
instruments.
Quality Assurance
   QAEML's quality assurance program, in direct sup-
port of Section 110 of the Clean Air Act, involves the
development of guidelines describing techniques that
can be used to:

   •  Provide  routine indication,  for operating pur-
      poses, of satisfactory or unsatisfactory perform-
      ance of personnel or equipment.
   •  Provide for  prompt detection and correction of
      conditions that contribute to  the collection of
      poor-quality data.
   •  Collect  and  supply  information useful to suc-
      cessfully describe the quality of the data.

   Four guidelines, each specific to one method, were
developed and published  for the  reference methods
Laboratory tests  are used  to evaluate various  methods  for  measuring ambient pollutant concentrations.

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for ambient air.   Similar documents are being de-
veloped for  stationary sources reference methods,
hazardous pollutant methods, fuel and fuel  additive
reference methods, and mobile source emission tech-
niques.
   Functioning of  any quality assurance program re-
quires the routine use of  reliable materials of known
composition, called "reference materials."  Such ma-
terials are obtained, and procedures are developed for
their use in  the calibration of equipment, in quality
control  checks of  components  of the measurement
process, and in activities that  document the  data
quality.   Interlaboratory performance  surveys  are
conducted periodically using  these materials. These
surveys evaluate overall performance of those organi-
zations participating.
   Among QAEML's  major accomplishments during
the reporting  period  was the initiation of work on
guidelines for  the  development  of quality assurance
programs, for use with the new stationary source per-
formance  reference methods, and for the reference
methods for the hazardous pollutants, mercury and
beryllium.
   Reference samples  were developed for use in qual-
ity control  programs  for measuring  SO2, CO, and
particulates  in  ambient air.   Several  interlaboratory
performance surveys  were conducted with the par-
ticipation  each  time of about 100 Federal, state, and
local laboratories.  Surveys were for measuring S02,
CO, and particulates in ambient air.
   Guidelines for quality  assurance program develop-
ment for the method  for measuring ozone, CO, SO2,
and  TSP  in the  ambient air  were   published and
distributed.
   Future QAEML research will  be aimed at develop-
ing quality assurance guidelines  for newly designated
reference  methods and revising  previously published
documents.  Test materials for use in interlaboratory
quality  control  performance testing  activities  con-
ducted  by EPA will  continue to be  developed and
refined; interlaboratory performance  surveys  will be
continued, perhaps at an expanded rate.


National Air Surveillance

Network

   The  National Air Surveillance Network (NASN),
operation  of which supports Clean Air Act Section
103, is a  network of  about  250 sampling sites dis-
tributed all  over the nation.  Routinely, once every
12 days during 1973,  the air at each site was sampled
for particulates,  S02,  and N02.  The amount of par-
ticulate matter  collected  on glass-fiber  filters was
measured, and the filters were  stored  in a  sample
bank.   Liquid samples  taken to measure N02 and S02
were analyzed promptly.
   A  direct-reading emission spectrometer,  used to
determine  simultaneously  some   25  trace-element
levels in environmental particulate  samples, has been
modified, greatly improving its precision and lowering
detectability limits for most elements.
   Several programs  for automated data acquisition
and analysis,  with built-in quality  assurance checks,
have been constructed, including numerous regression
analyses for determining precision.
   Among the year's major accomplishments was the
analysis of particulate  matter  samples collected in
1970 and 1971  for some  25 metals,  using the im-
proved optical emission spectrometer; the use of a
computer  reduced the time necessary to process the
162,250 data points produced.  Some 300 particulate
matter samples from  selected sites were  taken from
the particulate matter sample bank and analyzed for
benzo(a)pyrene.
   Personnel,  resources, and responsibilities  for rou-
tine NASN monitoring for TSP, SO2, and NO2 were
transferred to the regions  with minimal adverse  ef-
fects.  This transfer was accomplished through train-
ing of regional  personnel both at NERC-RTP and in
the field, and by furnishing complete written instruc-
tions  in all phases of the NASN activities. Sites were
visited, and equipment was  replaced  and/or  updated
as needed.  Quality assurance assistance was rendered
to all  of  the  EPA regional laboratories during this
transfer of responsibilities.  Performance audits for
analytical  portions of the  S02 and NO2  analyses
were  conducted.  QAEML  provided  in quantity the
samples whose concentrations were unknown  to the
recipients  on  a schedule such that  the quality  of the
performance of the routine analyses can be estimated.
This activity was  begun in 1973 and  continued  As-
sistance in quality control  of the  NASN techniques
was also begun in  1973 and will continue.
   Although  routine  operation of  the  NASN for
analysis of the weight  of  TSP, S02,  and N02 has
been  transferred  from QAEML to the regions, por-
tions  of exposed glass-fiber filters collected under re-
gional auspices are  still being received  and placed in
the sample bank.   Portions of archived filters will be
analyzed for  sulfates, nitrates, trace  metals, and  or-
ganic and  inorganic constituents to meet the require-
ments of QAEML's mandate.


Co n tin uousAir Mo n ito ring

Program

   The Continuous Air Monitoring Program  (CAMP),
in support of Clean Air Act Section 103, provides  a
current and ongoing  source of information relevant
to a wide range of problems associated  with air moni-
toring and surveillance, including operation, mainte-
nance, calibration, and  evaluation  of air monitoring
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                     ANNUAL REPORT 1973

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equipment.   This program provides  demonstration
and on-site training in the use of sophisticated state-
of-the-art instrumentation and procedures throughout
the United States.
   Continuous air monitoring instruments were evalu-
ated and optimized during the year, and calibration
techniques were  developed  to support regional needs.
CAMP stations in  Philadelphia, Denver, and Chicago
were  transferred  to  appropriate  regional offices.
Immediately  before the transfer, the equipment was
serviced, the  instruments  were calibrated,  and the
operators were trained.  The exterior of the St. Louis
station  was  replaced and incorporated into the Re-
gional  Air Monitoring System (RAMS). The Cincin-
nati  station  was disassembled and removed because
the site lease could not be renewed.
   The  Durham  Air Monitoring and  Demonstration
Facility (DAMDF) was  utilized to conduct an N02
methods comparison study and to evaluate the  pro-
posed  equivalency regulations.   Four  methods,  cur-
rently  being considered  as candidates for a new refer-
ence method  for  measuring  N02,  were extensively
evaluated  during November and  December  of  1973
to determine the comparability of data collected by
each  method.   The  study was conducted at the
DAMDF utilizing a special  ambient air manifold sys-
tem from which duplicates of each of the four meth-
ods could simultaneously sample ambient air spiked
with various levels of N02.  Data were collected con-
tinuously  for  36 days  under  various  conditions of
N02 and other  ambient pollutant levels.  Results of
this study are currently  being  evaluated  and will be
used  to assist in  the selection of  a  new  reference
method for N02.
   The  DAMDF  is now being  remodeled to include
an  improved system for environmental control  and
general  building maintenance.
   The  latest available continuous monitoring instru-
ments  are to  be installed at DAMDF   This special
multipurpose facility will then  be utilized to demon-
strate  advanced  air  monitoring techniques, to  test
and field-evaluate commercially available  ambient air
monitors and associated calibration and data acquisi-
tion techniques  to gather pollutant data, to conduct
intermethod comparability  studies, to provide on-the-
job training,  and to conduct  equivalency testing.
Operation of the Washington, D.C., station  will con-
tinue,  and  updating of the station will be  initiated
(within resource  availability).


Fuels Surveillance Network

   Fuels and fuel  additives are collected nationally
and analyzed for physical  characteristics and chemi-
cal composition  in support of Clean Air Act Sections
211 and 313.
   During the past year, fuels and fuel additives were
collected and  analyzed  routinely.   Analyses  of  the
1500  samples  collected in  1972 were completed in
1973.  Some certified fuel standards were developed.
A  round-robin  test of the  trace-element content of
fuels was conducted by some four dozen laboratories
using  various methods.  A  paper, "EPA's Fuels Sur-
veillance Network: Trace Elements in Gasoline,"  was
published.  The collection  and  analysis  of fuels  and
fuel additives  is an ongoing effort.   Results will be
made   available  promptly  to appropriate  decision-
making organizations.
   QAEML  contributed  to  the development of  a
simple,  but  accurate  field test for detecting lead, an
atomic  absorption spectrophotometric  method  for
detecting  lead  in gasoline  (ASTM-D3237),  and  a
method for detecting  phosphorus in gasoline (ASTM-
D3231).
   Fuel and fuel  additive samples were  analyzed for
possible enforcement  actions.  Chain-of-custody  was
maintained so that samples could meet  legal eviden-
tiary  tests.  Samples  for possible enforcement were
analyzed as received  (in most cases, a rapid response
was necessary.)  Programs for automated data  acqui-
sition  and analysis have  been constructed,  including
numerous regression  analyses for determining preci-
sion for internal quality control.
   Areas of future study  include  improvement of
techniques  for  trace-element  definition  by  spark-
source mass spectrometry, neutron-activation  analy-
sis, and X-ray fluorescence.  A computer program to
support  neutron-activation  analysis  is  being  devel-
oped,  and  work  is continuing  on methodology for
analysis for  sulfur, lead,  and phosphorus in fuels in
support of the fuel regulations for OEGC.


Membrane Filter and

Precipitation Networks

   In  support of  Clean Air Act Section  103, opera-
tion  of the  55-station membrane filter  network for
particulates  was maintained;  samples were collected
and analyzed for atmospheric pollutants of interest.
QAEML  supported a  20-station  Precipitation Net-
work  operated jointly by EPA,  the National Oceanic
and Atmospheric Administration, and the World  Me-
teorological  Organization  (EPA-NOAA-WMO); sam-
ples were analyzed for trace contaminants-  Several
programs were developed for automated  data acquisi-
tion  and  analysis, some of  which include built-in
quality control checks.
   During the year, archived samples collected by the
55-station membrane  filter  network were  analyzed
for asbestos.   Some 7,000 analyses were performed
on precipitation network samples, and the data were
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provided to interested  parties.  Membrane filter and
precipitation  monitoring  will be maintained roughly
at present levels.


Technical Assistance and

Rapid Response Sampling and

Analysis

   Much of QAEML's activity is prompted by needs
for technical assistance in other portions of EPA.  For
purposes of this report, QAEML's responses to these
"outside" needs are described as a group.
   During the past year, QAEML developed and opti-
mized  methodology for assessment  of levels of mer-
cury that  may  have  an  adverse effect  on  human
health.  The Laboratory also developed and published
a method for the  sampling  and analysis  of ambient
elemental mercury.
   At  the  request of  EPA's Office of  Air Quality
Planning and Standards,  several special studies  were
conducted to determine  the  levels of criteria pollut-
ants.   For example, EPA  disapproved State Imple-
mentation  Plan smelter regulations; therefore, a spe-
cial network was implemented to determine the levels
of S02 in the vicinity of  1 2 smelters to provide infor-
mation unon which to base a control strategy to meet
the national secondary  ambient air quality standards.
Specifications  were  developed for  the  monitoring
equipment,  sites were  selected,  stations  were in-
stalled, standard operating and quality control proce-
dures were developed, operators  were trained,  and
instruments were calibrated.  The network consisted
of 23  sites with continuous analyzers,  40 sites with
integrating samplers, and 12 meteorological stations.
Integrated  samples were  taken  daily,  and  some
30,000 samples were  analyzed for  S02  under con-
tract.  The validated data were submitted to OAQPS
and to  appropriate Regional Offices.
   The  levels  of N02  are being determined  at 20
selected  stations in  Air  Quality  Control  Regions
(AQCRs)  that  may need to  be  reclassified.   The
latest state-of-the-art continuous  monitoring  instru-
ments  for  N02 were  used at 42  sites  in selected
AQCRs.   Mandated reclassifications were promul-
gated based on the decision-making  data gathered by
this operation.  The present network now consists of
the 20 stations chosen for continuing evaluation in
areas of elevated ambient NO2 levels. All equipment
is calibrated at 4- to 6-week intervals. The validated
data are utilized to reclassify the appropriate AQCR
with respect  to the primary ambient NO2 standard.
   QAEML  responded  to  a request by OEGC for
assistance in  gathering air  quality data  for asbestos
in the  city of Duluth  and in the vicinity of the Erie
Mining Company and the Reserve Mining Company
for possible enforcement action. From June 17 to 30,
1973, a total of 11 sites were monitored in the above
areas.  QAEML calibrated samplers, trained personnel
doing the sampling, and provided technical assistance
in  chain-of-custody procedures.
   OEGC later requested a second extensive asbestos
air monitoring study.  The August 7-16, 1973, study
consisted  of monitoring asbestos levels in Metropoli-
tan Duluth,  the  iron ore  loading.dock in Duluth, and
the vicinity  of  Erie Mining Company's site at Hoyte
Lake.  This time QAEML provided equipment opera-
tion  and  data  reduction.   Chain-of-custody  proce-
dures were used for all asbestos samplers at the nine
sites.
   QAEML's technical  assistance rendered  in initiat-
ing the Southwest Energy Study consisted of develop-
ing equipment  specifications,  procuring  hardware,
selecting sites, and  preparing operating instructions.
Installation  and calibration  assistance  was also pro-
vided on-site by field personnel.
   At the request of OAQPS, a complex source study
to obtain ambient CO concentrations was conducted
at  various shopping centers.   Indoor and  outdoor
levels of CO  were determined and compared.
   Environmental samples, including those of  biologi-
cal origin, were analysed for trace-metal constituents.
Instrumental techniques (including atomic-absorption
spectroscopy,  spark-source  mass spectroscopy, neu-
tron-activation  analysis,  and  optical-emission  spec-
trometry) are used  for  trace-constituent analyses  in
animal  and  plant tissues,  soil and  water samples,
particulates, and fuels.  Services being  performed in-
clude analysis of biological tissues exposed to metal
aerosols,  preparation  of metal aerosol samples  by
particle  size  fractions, development of the  Anodic
Stripping Voltameter for analysis  of trace  metals,
and development of atomic-absorption  spectrometric
techniques for  analysis of serum  and tissue samples.
   An  impaction collector, for collecting particulate
matter according to particle size, was evaluated  in
the field; results were  submitted to the Emissions
Measurement Branch  of OAQPS.
   QAEML  personnel assisted OAQPS  in making on-
site  analyses and in obtaining source samples that
were  analyzed  to  determine data necessary  for the
setting of standards of performance for new  station-
ary sources.   Sources  involved in this  effort have
been kraft mills and refineries.
   Source samples obtained from  chloro-alkali plants
and  from phosphate  fertilizer plants were analyzed
for mercury and fluorides, respectively.
   Future work will  include determination  of atmos-
pheric levels of TSP, sulfate, nitrate,  platinum, pal-
ladium,  and  ruthenium  in special samples taken  in
Southern California before and after introduction  of
catalytic converters on automobiles.
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   Methods will  be developed for the determination        An experimental network  for  the determination
of trace  elements  of interest in biological matrices      of  elemental  mercury in ambient air will  be  imple-
such as serum and  tissue. Technical assistance will be      mented in the coming year.
provided in analyzing both special samples and NASN        Research  and development will be  conducted to
samples for metal  and non-metal inorganics. Special      determine the precision  of sampling and analysis of
networks will be developed and maintained to gather      precipitation and the effects of storage of samples on
data to  show the  influence  of the automobile  cata-      the analytical data obtained.
lysts on the nature and extent of sulfur species in the
air and to define background levels of ozone and the
patterns of transport of ozone through the air.
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Meteorology
  Laboratory

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                                                       OVERVIEW OF ML'S MISSION
 Meteorology
    Laboratory
METEOROLOGY
LABORATORY
•••
•am
•••
•••

REGIONAL AIR POLLUTION
STUDIES BRANCH

MODEL DEVELOPMENT
BRANCH

ENVIRONMENTAL APPLICATIONS
BRANCH

CLIMATIC ANALYSIS
BRANCH

SPECIAL PROJECTS
BRANCH
Studies of the flow and diffusion of pollutants around
building, highway configurations, and complex terrain
are conducted in a  wind tunnel by  the Meteorology
Laboratory.
   The  Meteorology  Laboratory  (ML)  provides an
accurate description of the role and interrelationships
of atmospheric processes  in effective air, water, and
land resource management. It  provides direct consul-
tation  and  technical  meteorological  services; and,
through grants, contracts, and  personal contacts, pro-
motes meteorological  research  in concert with EPA's
efforts  to  improve and  protect  public health and
welfare.
   ML's contribution  to efforts to control air pollu-
tion lies in the delineation of  the  effects of weather
and climate on air pollution as well as the  effects of
air pollution on weather, visibility,  and climate. Theo-
retical  and experimental  research  into the physical
processes  that affect  the  transport, diffusion, trans-
formation, and disposition of air pollutants in and
from  the  atmosphere  leads to improved techniques
for determining and  forecasting  meteorological  as-
pects of air pollution  on a local, regional, or national
basis. To this end, the Laboratory develops, evaluates,
and disseminates  analytical diffusion  models, which
are used to predict the temporal and spatial distribu-
tion of  air pollutants. ML also develops sensing tech-
niques  for measuring  meteorological  parameters in
urban  and rural  areas  and provides  meteorological
support to EPA offices and activities in their abate-
ment and compliance efforts.

LEGISLATIVE MANDATE

   The  major Laboratory  effort is  directly  related to
the requirements of Section 103 of the Clean Air Act;
however, efforts are also in support of Sections 110,
303, and 313. Pertinent portions of these Sections are
quoted  below, followed  by brief discriptions of the
types of supportive actions taken by ML.

   "RESEARCH,  INVESTIGATION,   TRAINING,  AND
   OTHER  ACTIVITIES
   Sec. 103. (a) The Administrator shall establish a national
     research and development program for the prevention
     and  control of air pollution and as  part  of  such
     program shall—(1) conduct,  and  promote the coordi-
     nation  and acceleration of, research, investigations,
     experiments,  training,  demonstrations, surveys, and
     studies relating to the causes, effects, extent, preven-
     tion, and control of air pollution; . . ." (3) conduct in-
     vestigations and research and make surveys concerning
     any specific problem of air pollution  in cooperation
     with  any air pollution control agency with a view to
     recommending a solution of such problem, if he is re-
     quested to do so by such agency or if, in his judgment,
     such  problem may affect any community or communi-
     ties in a State other than that in which the source of
     the matter causing or contributing to the pollution is
     located;  .... "(b)  In carrying out the provisions of the
     preceding subsection the Administrator is authorized
     to-
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     "(1) collect and  make available, through  publications
     and other appropriate means, the results of and other
     information,  including appropriate  recommendations
     by  him in connection therewith, pertaining to such
     research and other activities.
     "(2) cooperate with  other  Federal  departments  and
     agencies, with air pollution control agencies, institu-
     tions,  and organizations,  and  with  any  industries
     involved,  in  the preparation and  conduct of such
     research and other activities;
     "(3) make grants to air pollution control agencies, to
     other public or nonprofit private agencies, institutions,
     and organizations, and  to individuals,  for purposes
     stated in subsection (a) (1)  of this section;
     "(4) contract with public  or private agencies, institu-
     tions, and organizations, and with individuals . . .;
     "(7) collect   and disseminate,  in cooperation with
     other  Federal departments  and agencies,  and with
     other  public  or private  agencies,  institutions,  and
     organizations having  related responsibilities, basic data
     on chemical, physical, and  biological effects of varying
     air quality  and  other information  pertaining to  air
     pollution and the prevention and control thereof; .  . .
     "(f) (1) In carrying out research pursuant to this Act,
     the Administrator  shall  give  special  emphasis  to
      research on  the short- and long-term effects of  air
      pollutants on   public health   and  welfare.  In  the
      furtherance of  such  research,  he  shall  conduct an
      accelerated   research  program— ...  (B) to improve
      knowledge of the short- and long-term  effects of air
      pollutants on welfare.
      "(2) In carrying out the provisions  of this subsection
      the Administrator may— . . . (C) utilize, on a reimburs-
      able basis, the facilities of existing Federal scientific
      laboratories and research  centers; (D) utilize the au-
      thority  contained  in paragraphs (1)  through  (4) of
      subsection (b); and  (E) consult with other appropriate
      Federal  agencies to  assure  that research  or  studies
      conducted pursuant  to this subsection will be coord-
      inated with research  and studies of such other Federal
      agencies."
   EPA's research responsibilities, as outlined  in the
portions of the Clean Air Act cited above, constitute
the  Meteorological  Laboratory's  principal  mission.
The Laboratory also provides direct assistance  in the
evaluation of environmental impact statements.

   "IMPLEMENTATION PLANS
   "Sec. 110. (a) ... (2) The Administrator shall . . . approve
      or  disapprove such (state-submitted implementation)
      plan  or  any  portion thereof. The Administrator shall
      approve such  plan, or any portion  thereof, if he
      determines that it was adopted after reasonable notice
      and hearing and that— . . .  (C) it includes provision for
      establishment and operation of  appropriate  devices,
      methods,  systems,  and   procedures  necessary  to
      (i)  monitor, compile, and analyze data on ambient air
      quality . . ."
   Laboratory  assistance provided by the  Meteoro-
logical  Laboratory  in  support of  the evaluation and
enforcement of state implementation plans by EPA is
a component of Section 110 of the Clean Air Act.
   "EMERGENCY POWERS
   "Sec.  303.  Notwithstanding any other provision of this
      Act,  the Administrator . .  .  may  bring  suit ...  to
      immediately restrain any person causing or contribut-
      ing to (the) alleged pollution to stop the emission of
      air pollutants causing or contributing to  such pollution
      or to take such other action as may  be necessary."
   "ADDITIONAL REPORTS TO CONGRESS
   "Sec.  313 ... the Administrator shall  report to Congress
      on measures taken toward  implementing  the purpose
      and intent of this Act .  . ."

   The  Meteorological  Laboratory  provides  direct
support to EPA's exercise  of emergency powers under
Section  303  of  the  Clean  Air Act. The  Laboratory's
assistance  is also provided in support of Section 313
of  the  Clean  Air  Act   to  prepare meteorological
portions of reports to Congress.
   Table  13  contains a  summary  of the resources
employed  by ML  for  Fiscal Year  1974 in  support of
the applicable sections of the Clean Air Act.
ORGANIZATION

   The  Meteorology   Laboratory   consists  of  five
Branches:  Model  Development. Environmental Ap-
plications, Climatic  Analysis,  Regional  Air Pollution
Study (RAPS),  and  Special  Projects.  The activities
and   research  programs  of  these   five  Branches  in
furtherance of the Laboratory's mission are described
briefly below.


Table 13.  SUMMARY OF RESOURCES FOR METE-
OROLOGICAL  LABORATORY FOR FISCAL YEAR
                         1974
Section of
Clean Air
Act sup-
ported
103
110
303
313
Totals3


Funds,
$103
5940
275
36
50
6301



Positions
49
12
—
—
61


Approximate
percent
94
4
1
1
100
 aDoes not  include $0.5 million of special energy appropria-
 tions,  but  includes 47 positions loaned under  interagency
 agreement with National Oceanic and Atmospheric Adminis-
 tration.
Model Development Branch

   The  Model  Development  Branch  develops  the
analytical and  numerical formulations (i.e.,  meteoro-
logical dispersion and statistical techniques  models)
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                        ANNUAL  REPORT  1973

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Solar  tracking instruments are used to track the sun. measure the intensity of solar radiation, and indirectly
provide a measure of atmospheric aerosol concentration.
 that are used to estimate relationships between source
 emissions having  any specified distribution and the
 resultant air quality throughout any specified region.
 The Branch also conducts theoretical and experimen-
 tal studies to  improve the understanding of physical
 processes affecting the transport, diffusion, transfor-
 mation, and ultimate disposition of pollutants in and
 from the atmosphere.

 Environmental

 Applications Branch

   The Environmental Applications Branch evaluates
 new and existing meteorological dispersion  and statis-
 tical  techniques  and models and adapts  them to
 recurring user applications.  The  Branch  maintains
 liaison with groups applying  and developing models
 to provide guidance and advice  and  to  ascertain
 future model needs at the user level.

 Climatic Analysis Branch

   The Climatic Analysis Branch develops and applies
 techniques of  meteorological data  analysis and pre-
sentation to provide information on the potential for
atmospheric dispersion of air pollutants in a specific
geographical area. The Branch  determines empirical
relationships between air quality data, meteorological
parameters, physical processes governing observed air
quality, and site characteristics. Through a national
and international  cooperative network. Branch per-
sonnel  monitor atmospheric turbidity  and  establish
seasonal values, geographical variations, and long-term
trends. Field experiments are designed and conducted
to determine the radiant  energy  balance of earth-
atmosphere  systems  in  both urban  and rural loca-
tions.  The Branch evaluates and studies the collected
data by incorporating them into  radiation  transfer
theories for variously  polluted and clean atmospheres,
and thereby establishes effects  of  pollutants on  the
energy balance,  which then affects pollutant distribu-
tion.

Regional Air Pollution Studies

(RAPS) Branch

   The Regional Air  Pollution Studies  Branch devel-
ops,  implements,  and manages a  comprehensive re-
search  program to define and describe air pollution
Meteorology Laboratory
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transport and transformation processes in the atmos-
phere on a regional scale. It coordinates the activities
of other agencies, both  public and  private, that are
conducting field experiments pertinent to  RAPS to
ensure that the broad program of research, develop-
ment, and field experimentation directed  toward the
acquisition, verification,  and  evaluation of basic data
for models used to describe and predict the transport,
dispersion, and concentration of pollutants in the
regional  area  is conducted  in an  appropriate and
economical manner.
Special Projects Branch

   The Special  Projects Branch provides  continuing
technical guidance and  staff  support  to  EPA com-
ponents,  including the  Regional  offices, to  ensure
that appropriate meteorological  information  is pro-
vided in abatement,  compliance, and  other  opera-
tional activities. The  Branch  collects  and evaluates
environmental  quality  and  meteorological-climato-
logical information appropriate  for  application to
power plant  or  industrial engineering requirements,
design of  monitoring networks, support  of legal
actions, and studies of possible effects of air pollu-
tion.  In support of EPA Regional Offices, consulta-
tion and other  meteorological  assistance  is provided
to State and local air pollution control agencies. Field
support  is  provided  in  air pollution  emergencies.
Liaison  is  maintained  with  the  National  Weather
Service through  participation in the work of inter-
agency committees.
PHYSICAL FACILITIES

   In addition to the usual meteorological instrumen-
tation,  the   Laboratory  possesses  a  mobile lidar
(laser-radar)  unit, a microwave thermosonde system,
special  meteorological  sensors for studying surface
energy fluxes, special equipment for sensing short-
and long-wave radiation, and a small wind tunnel. The
sunphotometers  used in  the national  and  interna-
tional turbidity  networks are  tested, repaired,  cali-
brated,  and   occasionally  built in the Meteorology
Laboratory.  The  Laboratory's small  wind tunnel is
used  to  physically demonstrate  the dispersal of a
pollutant from a scale-model source.  A large, sophis-
ticated wind tunnel is expected to be in operation by
early  1975.  This  new  device  initially will  be an
open-return, non-stratified tunnel  with a test section
that is  3.66  meters  (12  feet)  wide,  2.13  meters (7
feet)  high,  and  18.29 meters (60 feet)  long with a
maximum air flow speed  of 7.62 meters (25 feet) per
second.
MAJOR PROGRAM AREAS

   Meteorology Laboratory activities can be function-
ally divided  into five areas: development, evaluation,
and  validation  of air  quality  models;  innovative
development in air quality simulation models; deter-
mination of patterns and levels of pollutant emissions
from  large power  plants; determination of pollutant
and thermal  emission effects  on visibility, weather,
and climate; and  meteorological  support for  abate-
ment and compliance efforts.
   Unless  indicated otherwise, the research activities
discussed  in the following  paragraphs represent con-
tinuing efforts by ML or its contractors in support of
Section 103  of the  Clean Air Act.
Air Quality Models

   Information on the meteorological effect of pollu-
tant concentrations on  prospective control  strategy
decisions and  land-use plans is provided by  models
describing  temporal  and  spatial  variations   in  air
quality. To facilitate the application of models, the
air  quality  simulation  models and  related  data for
various  pollutants are  stored at a central computer
facility, called the User's  Network of Applied  Models
of Air Pollution (UNAMAP).


   • APRAC—Provides  the hourly  average  carbon
     monoxide  level  as  a  function  of extraurban
     diffusion  from automotive  sources in upwind
     cities,   intraurban  diffusion   from  roadway
     sources,  and  local   diffusion  within  a  street
     canyon.
   • HI WAV-Estimates  highway-related  air  pollu-
     tion for  receptor locations that are downwind
     of at-grade and cut  highway sections.
   • COM—Provides  long-term  average  pollutant
     concentration.
   • PTM AX—Estimates  the  maximum   hourly
     average   ground-level  concentration  from  a
     single stack as a function of stability and wind
     speed.
   • PTDIS—Estimates the hourly  average  ground-
     level  concentration  from a  single stack at a
     specified downwind distance.
   • PTMTP-Estimates the average hourly  concen-
     tration  at  up to 30  receptors from up to  25
     sources.


   Reactive pollutants  and inert  pollutants  are  the
two  major areas  of  concern in efforts to   model
transport and  dispersion  characteristics  from  single-
line and area sources.
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                     ANNUAL REPORT 1973

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Reactive Pollutant Models
Additional Modeling Work
   Three  private  research  organizations  under con-
tract to ML developed separate air quality simulation
models  for  reactive  pollutants. Two of the models,
one by  Pacific Environmental Services (PES) and one
by General  Research  Corporation (GRC), are  quasi-
lagrangian  or ''trajectory" models.  These models
follow  an  air parcel, a body of air within  which
chemical processes occur as the air moves over various
emission sources. PES assumes that  the  atmosphere
consists of a single well-mixed vertical layer  between
the surface  of the earth and the top of the mixing
layer; GRC  assumes a multilayered vertical structure.
PES  uses  a  33-reaction kinetic module; GRC  uses a
16-reaction   kinetic  module.  The  basic  difference
between the two models lies in  the  handling  of the
hydrocarbon reactions.
   System Applications, Inc. has developed  a "grid"
or  Eulerian  model   that   is  basically  a  three-
dimensional  multi-box representation.  This  model
divides the mixing layer into a maximum of 10  layers,
the horizontal scale  is 2 miles by 2 miles for  a grid
square.  The  15-reaction kinetic  module is similar to
the GRC model.
   In  each of these three models the meteorological
parameters are input; they are not predicted by the
model.  All three  are  single-day,  daylight models and
all are relatively  crude  first generation efforts.
Inert Pollutant Models

   The  Meteorology   Laboratory's  effort  in  inert
pollutant modeling includes: modification and testing
in the Los Angeles basin  of the urban  meteorology
and  pollutant  model  developed  by  the  Center of
Environment and  Man; evaluation  of Northern En-
gineering  Research  Corporation's  airport  model  by
Geomet, Inc., based  on observations  made at Wash-
ington National Airport;  development and use of a
computational  procedure  for  estimating  maximum
24-hour concentrations that occur once per year from
a single power plant emitting pollutants  from one to
six stacks; initial development of a  versatile short-
term  model for urban  areas with  a stagnation sub-
model for  use  in episode  control; development and
use of a screening  procedure  to evaluate  in  broad
terms the  impact (relative  to the air quality standard)
of a  point source releasing  a  nonreactive  pollutant;
evaluation  by  Geomet of a gaussian plume  urban
diffusion  model; development and  testing  by  Los
Alamos Scientific Laboratory  of a numerical  model
of air pollution transport  in  street canyons;  and
evaluation of an analytical and experimental study of
diffusion in the turbulent surface layer.
   Pennsylvania  State  University,  under  an  EPA
grant, conducted  studies on  the  development of a
three-dimensional  meteorological and air quality pre-
diction  mesoscale  model,  on  a  parameterization
scheme  for incorporating  the  effects  of  sub-grid
fluxes  into  a  regional model,  on the modeling of
sub-grid turbulent transport applicable to microscale
modeling  of the urban  environment, and  on the
interpretation of  remote  sensing data with emphasis
on  interpretation  of acoustic radar  signals to deter-
mine vertical wind and temperature profiles.
   Stanford  Research  Institute conducted two  stud-
ies: one to observe the photochemical smog  over San
Francisco   by  attempting  to track an  air  parcel
crossing San Francisco Bay; and the other, to measure
the geophysical characteristics and energy budget of
the urban surface  in the St. Louis area.
   A study of the dispersion,  transport, and removal
of  airborne pollen  was conducted by  the  State
University  of  New  York  at Albany.  Preliminary
results  suggest that  source configuration and  local
meteorology are  critical  factors. The University of
Wisconsin  at Milwaukee is studying  the transport of
pollution by and within lake-breeze circulation.
   In  September  and October  of  1973,  a  field
program—Los  Angeles Reactive Pollutant  Program
(LARPP)—was  conducted in the Los Angeles basin to
obtain  air  quality and meteorological data  for the
development and  evaluation of "trajectory"  air qual-
ity  simulation models for reactive  pollutants. Work is
also being conducted  at the University of California
at Los Angeles, using a wind tunnel, cloud chamber,
and  rain  chamber,  to  determine   the  scavenging
efficiencies of precipitation  for atmospheric  aerosols.
   The first generation air quality simulation models
for reactive pollutants previously  mentioned  and
other   existing  photochemical   models  are  being
analyzed and evaluated. A  second generation model
that will include  revision of  the  chemical  reaction
module, provision for multi-day simulation, inclusion
of  the  sulfur  reactions,  and improvements in the
meteorological components is under development.
Innovative Air Quality Models

   New and improved concepts and methodologies
for use in the  development and  evaluation of air
quality  simulation  models having a broader,  more
comprehensive capability  to  predict the air quality
distribution under various  emission, topographic, and
meteorological   conditions  are  being   developed.
Among  the  technologies applied  to the solution of
practical problems will be  the fluid modeling facility.
Meteorology Laboratory
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(The wind tunnel  for the facility is currently under
construction.)
   Efforts,  most  of  which  are  now  in  progress,
include the  development  of   a  three-dimensional
model  of  the  wind  and  temperature  field,  as  a
function  of time  and  space,  in  a  region  extending
about  SOX 30 kilometers horizontally and 2  kilo-
meters vertically.  Currently,  work on  this  model
concerns:  specifying boundary  conditions  that will
allow nesting of the model in  a larger scale model;
incorporating  a  meaningful  surface  balance;  and
developing additional equations for the generation of
turbulent  dissipation  and turbulent energy required
for parameterizing the subgrid scale dynamics.
   Aeronautical  Research  Associates  of  Princeton,
Inc., under contract to EPA, is applying its invariant
modeling  concept to the analysis of diffusion under
three conditions:  in an  unstable surface atmospheric
layer capped by temperature inversion, from a point
source in  three spatial dimensions, and in  the Ekman
spiral of the planetary boundary  layer.
Large Single-Source Models

   The  transport  and  dispersion characteristics  of
pollutants from large single sources have been studied
and  modeled.  Field studies were  conducted to pro-
vide  data for the evaluation  of plume dispersion
models  capable of calculating ground level concentra-
tions of effluents from  single sources with tall  stacks.
Information on the chemical transformation of pollu-
tants within the plume  was also collected to assist in
modifying  the plume  dispersion  models.   These
models  will  be used to determine the impact of large
single sources on a region's air quality.
   The  large power plant effluent study (LAPPES) in
Western Pennsylvania was completed in 1970.  Analy-
sis of the data is continuing, with current emphasis on
the analysis of observed plume dispersion parameters.
The  observations were  made in the  vicinity of three
large, coal-burning, mine-mouth power plants as each
plant was constructed,  came on-line, and went into
full operation.
   Preliminary work has been done on the problem of
integrating the emissions from a large single-point
source  of reactive  pollutants  into  an air quality
simulation model  for reactive pollutants in  a region.
   Field studies are underway in cooperation with the
Tennessee Valley Authority (TVA) to measure chemi-
cal transformation in a fossil-fuel power plant plume.
The  study  is  concerned with the dispersion and
interaction of sulfur dioxide,  sulfuric  acid,  nitrogen
oxide, ozone, and particulates in stack emissions from
coal-fired  power  plants. Analysis of  the  data has
begun.
   By  use of a water channel, Flow Research, Inc.,
under  an  EPA  contract, is examining the effects of
terrain features on the dispersion of plume pollutants.
Initial  work dealt with the dispersion of a plume in
the vicinity of two hills joined by a saddle.
Climatic Effects

   This work area encompasses the analysis of pollu-
tant effects of physical processes in the atmosphere,
the comprehensive examination and statistical  anal-
ysis of air pollution meteorology parameters, and the
assessment of the effect of meteorological and clima-
tological  parameters on air quality. Statistical,  numer-
ical, and experimental methods were used to  investi-
gate the effects  of air quality on  meteorology  and
climatology, and  to assess the effects of meteorology
and climatology on air quality.
   Work   in  this  area included:   analysis of  U.S.
rawinsonde data to obtain meteorological  data perti-
nent to  the preparation of dispersion  estimates for
large single-point sources,  initiation of an  investiga-
tion to develop an objective technique  for determin-
ing hourly mixing heights, and studies of atmospheric
turbidity and urban radiation.
   A study of the worst air stagnation episodes lasting
1,2,3, 4, and 5 days  at 62 rawinsonde stations in the
contiguous United States was conducted using mixing
height  and wind speed data covering a 5-year  period.
This  information can be  applied  to  models  of
atmospheric transport and diffusion processes during
episodes  of extremely slow dilution (air stagnation).
   A turbidity  network of 80  stations, 50 in the U.S.
and 30 in other countries, is maintained by EPA. The
instrumentation,   instrumentation  calibration,  and
instrument repair is provided by EPA. Data reduction
and publication is performed by the National Oceanic
and Atmospheric Administration (NOAA), with qual-
ity control assistance from EPA.
   The difference in  the radiation  budget between
rural and urban sites  was examined in the St. Louis
area. Observations were made of the incident global
and direct solar radiation, of  atmospheric turbidity,
of downward-directed long-wave irradiance,  and of
the particle content  of the atmosphere.  Preliminary
evaluation of the data indicates that 6.5 percent less
total solar energy is received  at the urban site  than at
the rural site.
   An  examination   is  underway  to  evaluate  the
relative importance of interurban  and interregional
transport of   air pollutants  and   to  identify  the
meteorological  conditions associated with significant
long-distance transport (greater than 100 kilometers).
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                      ANNUAL  REPORT 1973

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 Meteorology Support

   In support of Sections  110, 303, and 315 of the
 Clean  Air  Act,  Meteorology  Laboratory  provides
 technical  services to various  EPA  offices and pro-
 grams, and  to State and local agencies. The Labora-
 tory  also supplies meteorological  field  support to
 EPA's Emergency Team during critical air pollution
 incidents,  such   as  the  chloride  barge accident at
 Morgan  City, LA.  NOAA  meteorologists were  as-
 signed to the Monitoring and  Data  Analysis Division
 and  the Control Programs Development Division of
 EPA's Office of  Air Quality Planning and Standards
 and  to the  Quality Assurance  and  Environmental
 Monitoring  Laboratory and the Human Studies La-
 boratory of NERC-RTP.
 OAQPS Support

   During  1973, the Laboratory provided meteoro-
 logical support for three major studies conducted by
 OAQPS. First, the  impact  of smelting operations on
 sulfur dioxide concentrations in the Rocky Mountain
 area  was examined. Second, the effects of  granting
 variances to large, non-urban power plants, if ambient
 air quality  standards  were not  violated, were ex-
 amined.  Results of applying   ML's  24-hour single-
source  model to three Air Quality Control Regions in
Indiana indicated that large power plants could be
allowed to burn coal temporarily at the 1970 sulfur
levels without  violating  either  annual  or  24-hour
primary  ambient  air  quality  standards. Third,  an
investigation of possible intermittent control systems
showed  that such systems were viable control meas-
ures, but only for large, isolated, elevated sources of
sulfur dioxide.
   In addition  to  reviewing Environmental  Impact
Statements and providing expert testimony  in court
suits, ML personnel assigned to OAQPS analyzed air
quality  trends using data  from the National Aero-
metric  Data Bank.  Initial trend analysis focused  on
isolating meteorological  parameters that  may cause
short-term trends. Thus far only heating degree-days
and rainfall have been associated with the short-term
trends. A trend toward increasing suspended particu-
late levels was found to be associated with decreased
rainfall between 1968 and 1971  in the western states.
   Two meteorologists, assigned to  the Air Pollution
Training Institute presented the meteorological por-
tions of the Institute's  courses.  In  addition,  they
conducted three courses during the year: Air Pollu-
tion  Meteorology, Diffusion of Air Pollution—Theory
and Application, and Meteorological Instrumentation
in Air  Pollution.  They  also  conducted a  2-week
training course for  NOAA meteorologists responsible
for preparing Air Stagnation Advisories.
Solar radiation measurements are taken using instruments mounted on a meteorological tower near the Meteorolog-
ical Laboratory.  A crank-up tower and a temperature shelter can be seen to the left of the tower.
 Meteorology Laboratory
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                                                    NERC-RTP Support
                                 \
Atmospheric  turbidity is measured using a portable
sunphotometer developed at Meteorology Laboratory.
                                                       Meteorological personnel assigned to other labora
                                                    tories within NERC-RTP provide assistance and guid-
                                                    ance on meteorological and climatological criteria and
                                                    instrumentation.  In  addition, daily  summaries of
                                                    atmospheric stagnation conditions were prepared for
                                                    the Community Health  and  Environmental Surveil-
                                                    lance Study (CHESS) in  New York, NY; Birmingham,
                                                    AL;  Charlotte, NC; and  Los  Angeles, CA. A  proto-
                                                    type continuous monitoring station was installed at
                                                    Chapel  Hill, NC, to determine the best instrumenta-
                                                    tion for measuring temperature, dewpoint, and wind
                                                    velocity. This  instrumentation  will be part of the
                                                    Community   Health   Air  Monitoring   Program
                                                    (CHAMP).  Climatological assistance was provided for
                                                    an  asthma  study in southern  California. Studies are
                                                    underway  on  the  relationship  between  mortality
                                                    statistics and  maximum temperatures, and the rela-
                                                    tionship  between extremely  high  nitric  oxide  and
                                                    nitrogen dioxide concentrations in Chattanooga,  TN,
                                                    and atmospheric conditions in  the area.
114
                                                                       ANNUAL REPORT 1973

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   Control
  Systems
Laboratory

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                                                     OVERVIEW OF CSL'S MISSION
       Control
     Systems
 Laboratory
CONTROL SYSTEMS
LABORATORY

^•i
^•i
••

ENGINEERING ANALYSIS
BRANCH

GAS CLEANING AND
METALLURGICAL PROCESSES
BRANCH

CLEAN FUELS AND
ENERGY BRANCH

PARTICULATE AND CHEMICAL
PROCESSES BRANCH
Studies of the  operation of lime/limestone flue gas
scrubbing processes are conducted at a prototype test
facility by the Control Systems Laboratory.   The
facility (TVA's Shawnee Steam Plant, Paducah, Ken-
tucky) employs three types of 10-MW  equivalent
scrubbers:   the hydrofliter,  the  turbulent contact
absorber, and the venturi.
   The Control  Systems Laboratory (CSL) of NERC-
RTP  is  involved  in   a  variety  of  technical and
management  functions  directly  related  to the re-
search,  development,  and demonstration of equip-
ment and systems designed to abate, in a timely and
cost-effective manner,  the emission  of  atmospheric
pollutants from stationary sources  to  a level that
protects  public  health and  welfare,  and to do so
within the framework of our  nation's  energy and
environmental mandates.  Included in  this mission is
the  goal  of  developing  a complete data  base of
stationary source emissions and demonstrating ade-
quate technology to control  pollutant emissions so
that effective New Source Performance Standards and
Hazardous Pollutant Standards can be promulgated.
   CSL  has a high degree of expertise  in the manage-
ment of complex engineering research and develop-
ment projects; additionally, as the result  of 10 years
of experience as an organizational entity,  the Labora-
tory has developed other  major capabilities in efforts
to fulfill its mission:

   •  The Laboratory  has  established  a  technical
      information data base  to  support  EPA's deci-
      sion-making capabilities in the area of station-
      ary source air pollution control.
   •  The Laboratory has proven its ability to recon-
      cile environmental and industrial requirements
      in a  cost-effective  manner  by  working  with
      industry on joint programs to  solve  environ-
      mental problems.
   •  The Laboratory  has become an international
      forum  for communication concerning available
      technology  through  its recognized ability to
      objectively evaluate new concepts and  to share
      research results.
LEGISLATIVE  MANDATE

   The legislative mandates upon which CSL's several
programs are  based and the various Sections of the
Clean  Air  Act  requiring  Laboratory support are
shown  below  with a brief description of the types of
actions taken  to support that mandate or Section.

   "RESEARCH,  INVESTIGATION,  TRAINING,  AND
   OTHER ACTIVITIES
   "Sec. 103. (a) The Administrator shall establish a national
     research and development program for the prevention
     and control of  air pollution and  as part of such
     program shall —
     "(1) conduct and promote the coordination and accel-
     eration of research, investigations . . . demonstrations,
     surveys, and studies relating to the causes, effects . . .
     prevention, and control of air pollution. . . .
Control Systems Laboratory
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           "(b) In  carrying  out  the  provisions  of  the
      preceding subsection, the Administrator is authorized
      to-
      "(1) collect and make available, through publications
      and other appropriate means, the results  of and other
      information . . . pertaining to such research. . . .
      "(8) develop effective and  practical processes, meth-
      ods,  and  prototype  devices for  the prevention  or
      control of air pollution."

   In support of Sections 103  (a) and (b) of the Clean
Air  Act  (cited  above),  CSL   conducts  studies and
investigations to characterize emissions of pollutants,
to evaluate  control technology, and to predict the
impact of and  need for  controls in  the  future. The
Laboratory   conducts   research  to  develop  cost-
effective   controls  for   pollutants  from  stationary
sources and  demonstrates the  most promising control
methods.  Finally,  CSL  disseminates  the  research,
development, and demonstration results to the public
through seminars, professional meetings, and appro-
priate publications.


   "RESEARCH RELATING  TO FUELS AND VEHICLES
   "Sec. 104. (a) The Administrator shall give special empha-
      sis to  research and  development into  new  and  im-
      proved methods, having industry-wide application, for
      the prevention and control of air pollution resulting
      from the combustion of fuels. In furtherance of such
      research and development he shall —
      "(1) conduct  and accelerate  research  programs di-
      rected  toward development  of  improved  low-cost
      techniques for—
           "(A) control of combustion byproducts of fuels,
           "(B) removal of potential  air  pollutants from
      fuels prior to combustion,
           "(C) control of  emissions from  the evaporation
      of fuels,
           "(D) improving  the efficiency of fuels  combus-
      tion so as to decrease atmospheric emissions, and
           "(E) producing  synthetic or  new fuels which,
      when used, result in decreased atmospheric emissions.
      "(2)  provide for  Federal grants . . . and contracts . . .
      for payment of (A) . . .  cost acquiring . . . for research
      and development purposes, new or improved devices
      or methods having industry-wide  application of pre-
      venting or controlling discharges into the air of various
      types of pollutants. .  . .
      "(3) determine, by laboratory  and pilot plant testing,
      the results of air pollution research and  studies  in
      order to develop new or improved processes and plant
      designs to the point where  they can be demonstrated
      on a large and practical scale;
      "(4) construct, operate, and  maintain,  or assist  in
      meeting the cost of  ... new or improved demonstra-
      tion  plants  or processes  which  have  promise  of
      accomplishing the purposes  of this Act. . . ."


   Through   efforts  provided   for  under  Section
104  (a) of the  Clean Air Act  (cited above), CSL has
brought flue gas cleaning to the  stage of commercial
development, has developed techniques for the reduc-
tion  of nitrogen oxide (NOX) emissions  from combus-
tion   processes  by  as   much  as  50  percent; has
currently under demonstration a  commercially feasi-
ble  means  of reducing  carbon monoxide,  hydrocar-
bon, and particulate emissions  from coke ovens by 90
percent;  has  identified  promising  new combustion
techniques  such as the advanced  power  cycle  and
fluidized-bed  combustion; and has developed effec-
tive, low-cost processes for cleaning coal.

   "AIR QUALITY  CRITERIA  AND  CONTROL TECH-
   NIQUES
   "Sec. 108 . . . (b) (1) Simultaneously with the issuance of
      criteria  under subsection  (a), the Administrator shall
      .  . . issue  . . .  information  on  air  pollution control
      techniques,  which  information  shall  include data
      relating  to  the technology and  costs of  emission
      control. Such information shall include such data as
      are available or attainable technology and alternative
      methods of prevention and control  of air  pollution.
      Such information shall also include data on alternative
      fuels,  processes,  and  operating methods  which  will
      result  in  elimination  or significant reduction of emis-
      sions."
   In support of Section  108 (b) of the Clean Air Act
(cited  above), CSL is continually evaluating  new and
existing  stationary source  control  procedures  in  an
effort  to  develop and  maintain  a comprehensive data
base related to air pollution control techniques.

   "(STATE) IMPLEMENTATION PLANS
   "Sec. 110. (a)  (1) Each State  shall . . . adopt  ... a plan
      which provides for implementation, maintenance and
      enforcement of such  primary (and secondary)  stand-
      ard. . . .
            "(a)  (2) (B) it (the plan) includes emission limi-
      tations, schedules, and timetables for compliance. . .  .
            "(e)  (1) Upon application of a Governor . . . the
      Administrator may  . . . extend  (compliance period)
      ...  if ... the Administrator determines that—
                 "(A) One or  more emissions sources . .  .
      are  unable to comply with  . . . standard because the
      necessary  technology or  other  alternatives are not
      available. ...
            "(f)  (1) . . .  The Governor  . . . may apply to the
      Administrator to  postpone  the  applicability of such
      requirement to such  source.  ... If the Administrator
      determines that—
                  "(B) such source (or class) is  unable to
      comply with such requirement because the necessary
      technology or other alternative methods of control are
      not available or have not been available for a sufficient
      period of time . . .
                 "(D)  . . . then  the Administrator shall
      grant a postponement of such requirement."


   The Laboratory's  role in  the procedures required
by  Sections 110 (a),  (e), and (f) of the Clean Air Act
(cited  above)  is  primarily  that of providing expert
testimony relating to  the availability of  air pollution
control  technology.  CSL's  research,  demonstration,
and other evaluation  tools  provide the most compre-
hensive  data base  available  concerning  the state-of-
the-art of air pollution control technology.
118
                                                                                   ANNUAL  REPORT  1973

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   "STANDARDS OF PERFORMANCE FOR NEW STA-
   TIONARY SOURCES
   "Sec. 111. (b) (3) The Administrator shall,  from time to
      time, issue information on pollution control tech-
      niques for categories of new sources and air pollutants.

           "(d)(1)...  each  State shall  submit  to  the
      Administrator a plan  which  (A) establishes emission
      standards for any  existing source for any air pollu-
      tant. . . ."

   CSL,  in support of Sections lll(b)  and (d)  of the
Clean  Air  Act  (cited  above), evaluates the state-of-
the-art of air pollution control technology for various
stationary  sources  and,  based  on  projected  future
control needs, develops new control technology. The
predicted new developments and schedules  provide a
basis  upon  which  EPA  can set future New  Source
Performance Standards. For non-criteria pollutants,
the Laboratory's data  base  related to control capabil-
ity and emission levels provides a  basis  upon which
States may set  emission standards for any  pollutant
from  stationary  sources.

   "NATIONAL EMISSION  STANDARDS FOR  HAZARD-
   OUS AIR POLLUTANTS
   "Sec. 112. (b) (2) The Administrator shall,  from time to
      time, issue information on pollution control tech-
      niques for air pollutants subject  to  the provisions of
      this section.
           "(c) (2) The President may exempt any station-
      ary source ...  if he finds that the technology  to
      implement such standards is not available. .  . ."

   In  support of Sections  112 (b) and (c) of the Clean
Air Act (cited above), CSL's programs will identify all
air pollutants from stationary sources.  As the need
for control of these pollutants is indicated, through
its related research and  development program, the
Laboratory will  be able  to  identify  not  only the
specific sources requiring control,  but also the most
cost-effective approach for achieving that  control.

   "COMPREHENSIVE ECONOMIC COST STUDIES
   "Sec. 312. (a) ...  The Administrator . . . shall  make a
      detailed  estimate  of  the cost of carrying  out  the
      provisions of this Act  . . . and  a comprehensive study
      of the economic impact of Air Quality  Standards on
      the Nation's industries, communities, and  other con-
      tributing sources of pollution, including an analysis of
      the national requirements for and the cost of control-
      ling emissions to attain such standards of air quality.
   Among  the  activities  of  the  CSL,  related  to
Section 312 (a)  of the  Clean Air Act (cited  above),
are research  and  demonstration projects  leading to
the development  of  comprehensive data relating to
the cost of various air  pollution control techniques.
   Because CSL's programs simultaneously support
numerous  sections  of  the  Clean  Air  Act,  it  is
impossible  to allocate a given resource to  only one
Section of  the Act. For  example, a  CSL  flue gas
cleaning demonstration project supports Section 103
(Research, Investigation, Training,  and Other Activi-
ties); Section 104  (Research Relating to Fuels and
Vehicles);  Section   108  (Air  Quality  Criteria  and
Control Techniques); Section 110 (State Implementa-
tion Plans); Section III (Standards of Performance for
New  Stationary  Sources—in this  case for electric
utilities); and Section 312  (Comprehensive Economic
Cost Studies).
   Thus, although Table 14 does not display a direct
one-to-one relationship  between projects and individ-
ual sections of  the Clean Air Act,  it does convey the
general level of support that CSL's program provides
to various sections of the Act.

Table 14.  SUMMARY OF RESOURCES  FOR  CON-
TROL SYSTEMS  LABORATORY  FOR  FISCAL
                   YEAR 1974
Section of
Clean Air
Act sup-
ported
103
104
108
110
111
112
312
Totals3


Funds,
$103
4,030
3,546
1,934
1,934
3,675
967
32
16,118



Positions
24
21
11
11
22
6
-
95


Approximate
percent
25
22
12
12
22.8
6
0.2
100
aTotal is  for CSL's "base  program"; it does not  include
approximately $10.2 million of supplemental energy research
and development funds received during FY 1974.
ORGANIZATION

   The Control  Systems Laboratory consists of four
main  Branches.  Its Engineering Analysis Branch func-
tions  as a program monitoring and evaluation group.
The  other three Branches are engaged  in  projects
ranging from small-scale  experimental  studies and
exploratory research, through pilot-plant-size experi-
mental work, to prototype evaluations of equipment
large enough  to  permit  confident scale-up to full-size
commercial installations.

Gas Cleaning and Metallurgical

Processes Branch

   The  Gas  Cleaning  and  Metallurgical  Processes
Branch directs  and manages  a broad-based research,
Control Systems Laboratory
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development, and  demonstration program  aimed at
developing  processes and equipment for the removal
of gaseous  pollutants from  fossil-fuel  combustion
effluents and  of all  pollutants  from  primary  and
secondary operations  in the ferrous and non-ferrous
metals processing industries.
   Much of the work of this Branch relates to flue gas
scrubbing processes: lime/limestone wet scrubbing, at
both TVA's Shawnee  Plant and in Key West; double
alkali  scrubbing,  using  a  soluble  alkali   (usually
sodium)  solution;  Chemico Mag-Ox,  a regenerable
approach utilizing  magnesium  oxide; Wellman-Lord,
utilizing  a  sodium  sulfite/bisulfite  solution  with
thermal  regeneration;  Stone and Webster/Ionics,  uti-
lizing  sodium  hydroxide  solution with electrolytic
regeneration; Monsanto Cat-Ox, a catalytic oxidation
adaptation  of the contact sulfuric acid process; and a
completely cyclic ammonium sulfite/bisulfite process
with bisulfate regeneration. The Branch's metallurgy-
related activities include such iron and steel industry
areas  as coke  ovens, sinter  plants,  basic oxygen
process  (BOP)  furnaces, and iron foundry cupolas, as
well as work with pollutants from copper,  lead,  and
zinc smelters.
Clean Fuels and Energy Branch

   The Clean Fuels and  Energy  Branch is responsible
for research, development,  and demonstration  (in-
cluding  evaluation) studies relating to processes for
the production  or utilization of clean fuels or clean
energy as a means of air pollution control. Among its
activities are:  evaluation  of systems for removing
potential pollutants  from coal  and oil; critical air
pollutant  emission assessment  and  review of  new
energy technologies; development of generalized con-
trol technology  for air pollutant emissions from fossil
fuel combustion and conversion processes; evaluation
and development  of  combustion  modifications for
abating  the  emission  of nitrogen  oxides and  other
combustible pollutants  from all stationary combus-
tion  sources; and evaluation, environmental  assess-
ment,  and/or  development   of  new pollution-free
methods of generating and utilizing  energy.
   Combustion   modifications  for  the  control of
nitrogen oxides and other pollutants have been  (and
continue to be) the target  of  significant efforts of
Branch  personnel. Modifications being investigated
include: combustion with low excess air, recirculation
of flue gas,  staged combustion,  combustor redesign,
and fluidized-bed combustion. Investigations of fuel
cleaning have included fossil  fuels (coal, oil, and gas)
and waste products such  as municipal refuse.
Paniculate and Chemical

Processes Branch

   The Particulate and Chemical Processes  Branch is
active in three major areas: it identifies, develops, and
demonstrates generalized  particulate control technol-
ogy to support the needs of CSL  for technology to
control patriculate emissions from specific industries;
it  identifies, develops,  and  demonstrates technology
for controlling pollutant emissions  from the chemical
process  industries; and it provides process measure-
ment services to all CSL Branches.
   The  Branch's  work in   the  area  of particulate
control technology development has included studies
not only to  improve such conventional particulate
control  equipment  as  electrostatic   precipitators,
fabric filters, and wet scrubbers, but also to identify
and further  develop  such  completely  new  control
approaches as the Sonic Agglomerator, Steam-Hydro
Scrubber,  and Pentapure  Impinger. Its activities re-
lated  to the  control of air pollution  from chemical
process  industries include studies of a wide range of
organic  and inorganic manufacturing processes, com-
bustion  processes, and open sources.  The  Branch's
process  measurement  activities  encompass the selec-
tion,  verification,  and   further  development  of
sampling methods, analytical procedures, and process
instrumentation   required  for  CSL's   internal  and
external  research, development, and  demonstration
activities.


Engineering Analysis Branch

   The Engineering Analysis  Branch  is the Labora-
tory's program planning and evaluation  coordination
facility.  Additionally,  it  is  responsible for technical
and editorial services that  are  more effective when
they are provided centrally. Branch personnel provide
cost  control  and  contract management services to
individual  project officers and assist in the evaluation
of unsolicited proposals as well as in the review of
on-going  programs.  Staff specialists are  available for
consultation on specific technical matters.


PHYSICAL  FACILITIES

   Final relocation  of all CSL  personnel  to NERC-
RTP from several scattered  locations was effected by
the end of the fiscal year. CSL's laboratory facilities
include  a  flue-gas  generator;  bench-scale scrubbing
equipment; laboratories for odor problem studies and
for the  physical  characterization of particulates; an
electronics shop; and equipment for wet and  instru-
mental analyses.  CSL also  maintains and  operates a
                                                                           ANNUAL REPORT 1973

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self-propelled  van  and a  trailer  (both  40  feet  in
length) that are equipped to conduct full-scale investi-
gation of process streams.
   Pilot-size equipment in  the  NERC-RTP High Bay
Areas (Wings  G and  H-300) includes a model wet
scrubber; four baghouses for fabric filtration  studies;
a  laboratory for the evaluation of novel  particulate
control  devices; and a variety  of experimental and
commercial combustion  systems including furnaces,
boilers,  and a gas turbine instrumented  for  most
gaseous  pollutant  emission  measurements.   (Fuels
being investigated  are  coals, oils, gases,  and  other
liquid and gaseous  materials.)
   The  Laboratory's in-house  capability to  support
measurements programs  recently  took  a  significant
step forward with  the  installation, at  NERC-RTP,  of
the  first  aerodynamic  test facility specifically de-
signed for  studies  requiring large gas volumes (up  to
 15,000cfm) with  carefully controlled  velocity pro-
files and known chemical composition.
 MAJOR PROGRAM AREAS

   The accompanying diagram, showing air pollution
 control technology  interactions, presents an overview
 of the Control System Laboratory program. Because
 of the way various laws are written, and because of
 EPA's planning system, CSL's  program  is divided into
 elements  based  on  the control of individual pollu-
 tants. Obviously, however, to control  ambient  con-
 centrations of pollutants, the industries  producing the
 pollutants must be controlled.
   The first five industries to which  New  Source
 Performance Standards were applied are shown at the
 top  of  the  diagram.  The  methods  that   CSL  is
 improving or developing for air pollution control are
 shown at the bottom of the diagram. Inevitably, there
 is significant overlap between industry,  pollutant, and
 control method descriptions of CSL's  program. For
 example,  work  directed  toward  controlling sulfur
 oxides (SOX)  may involve clean fuels,  gas scrubbing,
 or advanced  power  cycles. On the other hand,  SOX
 gas scrubbing  may be applicable to  power  plants,
 sulfuric acid  plants,  and non-ferrous  smelters; and
 smelters may emit trace hazardous elements as well as
 SOX.
   For purposes  of discussion, this  portion  of the
 Report is  organized  by control of specific pollutants.
 The broad  applicability of a control method for more
 than  one  pollutant,  from more  than one  source,
 should be kept in mind when  analyzing the program.
 This interdependence of CSL  program components
 highlights  an important synergistic characteristic: for
 example,  a  change  in the  Laboratory's  combustion
 control research  program,  to  reflect changes in the
 nitrogen oxides (NOX) program philosophy, will also
affect CSL's program to control combustible particu-
lates—particulates  which may  include  carcinogenic
hydrocarbons, possibly the most hazardous of pollu-
tants.
   A  strong  cooperative  effort  has  been fostered
between   industry  and  government:  CSL's  major
control technology development/demonstration proj-
ects  have  been cost-shared approximately equally by
both  sectors.  Industrial  studies conducted by  the
Laboratory have resulted in initiation of such promis-
ing projects as various  flue gas desulfurization sys-
tems, advanced  power  cycles,  low-Btu gasification,
and  coke  pushing and  charging demonstrations. Be-
cause many aspects of air pollution control are nearly
equal in  importance,  CSL's  efforts are not  (and
cannot be) concentrated in any single area.
GAS



FUEL



COMBUSTION



FLUID-BED

Air pollution control technology interactions among
sources to  which new source performance standards
were first applied.


Particulate Control

   The  most  pressing  need  in particulate  control
technology is the development of commercially avail-
able and widely applicable fine particulate (microm-
eters in diameter) control technology to support the
establishment of  Fine Particulate Ambient Air Qual-
ity Standards.  Such  technology is generally inade-
quate and  currently  in  the early stages of develop-
ment under EPA sponsorship. This technology is also
Control Systems Laboratory
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acutely  needed   to   achieve   Hazardous  Pollutant
Standards  and associated  New Source  Performance
Standards  for trace metals, which have  already been
established or are planned for the near  future. In  an
effort  to   develop  this technology  as  rapidly  as
possible, CSL is currently working with  many (nearly
70) contractors, grantees, and consultants.
   Scrubbers, electrostatic  precipitators,  and fabric
filters are  currently the major  particulate collection
devices. These devices  are being up-graded by projects
concerned  with decreasing costs, increasing applicabil-
ity of these devices to a wider  range of sources, and
extending  their range of particle collection capability
to  smaller  particle  sizes.  In  addition,  entirely  new
concepts of  particle collection are being investigated.
   System  studies, completed for  each of the conven-
tional devices, define potential  areas of improvement
and new  applications. Long  range projects  include:
development of generalized  models for  existing col-
lectors, identification  and  laboratory scale testing  of
totally  new  concepts  in particle control technology,
and pioneering work in small  particle detection and
small particle generation equipment.

   Electrostatic Precipitation—\n an electrostatic pre-
cipitator (ESP), dust suspended in  the  gas stream is
electrically  charged  and passed through an  electric
field  where  electrical  forces cause the  particles  to
migrate  toward  a collection   electrode.  The  dust,
separated  from  the gas by  being retained  on the
collection  electrode,  is  subsequently  removed from
the  device.  In  a conventional  ESP,  the  dust  is
removed mechanically.  In  a wet ESP,  the  dust  is
removed by continuous washing of  the collection
electrode.
   CSL is conducting field tests of industrial ESP's  to
determine  the fine particle collection efficiency and
economics  of ESP systems. Recent results  indicate
that  properly  designed and   operated  ESP's are
capable of  controlling flyash from coal-fired  utility
boilers at an overall mass  efficiency in  excess of 99
percent. These same efficiency measurements indicate
that these  ESP's  are more than 90 percent efficient
on a mass  basis in collecting all particle size fractions
down to about 0.01 micrometer in diameter.
   ESP's are being redesigned  to  improve their  par-
ticulate collection efficiency, especially for fine parti-
cles  and high  resistivity dusts. This work includes
development of  special dust-conditioning methods,
particle charging  procedures, and collection  section
designs. The work on conditioning has resulted in the
discovery of the current-carrying mechanism in flyash
at high temperatures and the demonstration of a new
conditioning agent.

   Fabric Filtration-k typical fabric filter consists of
a  flexible  layer  of  porous  cloth through which  a
 dust-laden gas is passed to separate particles from the
 gas stream. Fabric filters have been used successfully
 for  many years to  collect  dusts  at temperatures as
 high  as about  290°C; however  comparatively little
 scientific effort has been expended to develop higher
 temperature filtration technology. Fabric filtration is
 one of the few techniques now capable of collecting
 very   small  particulate  matter.  Fabric  filters  are
 usually flat  or  tubular bags suspended in a structure
 known as a baghouse (see accompanying figure).
 CLEAN AIR
   OUTLET

 DIRTY AIR
    INLET
CELL
PLATE
Typical fabric filter baghouse.
   One  product  of  a fabric filter systems  study,
completed for CSL in 1970, is a technology  hand-
book intended as a guide in the design, development,
application, and  operation of fabric filter  systems.
The  study also recommended research and  develop-
ment for possible funding by EPA.
   Products of that research  over  the  period of this
Report  have  been  publications  that  relate woven
fabric structure to filtering performance and evaluate
122
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 new spunboncied nylons as filter media. Experimental
 work to  aid  in selecting optimum filter  cleaning
 methods has been completed: a report of that work
 will be issued late in 1974.
    Major effort has been directed toward characteriz-
 ing and  improving fabric filter  system  performance
 for capture of fine  particulates. Tasks  in this area
 have been  awarded  to  contractors  and  grantees, as
 well as being  pursued  in-house. Specific programs
 involve  the development  of  non-woven  media;  the
 development of high-velocity,  high-efficiency  filtra-
 tion techniques; and the construction of a  portable
 baghouse system for on-site field testing.

    Novel Paniculate  Collection Dei//ces-The cost of
 high-efficiency   particle  collection   from  industrial
 sources  by conventional  equipment of all  types
 (scrubbers, filters, ESP's) is high, in large part because
 the efficiency of most collectors decreases in the fine
 particulate  range. This  performance loss must, there-
 fore,  be offset  by large size  or high-energy  input.
 Devices  or systems based on new collection principles
 or on radical redesign  of conventional collectors are
 sometimes  offered by  private developers.  Presently
 proposed systems include sonic agglomeration, granu-
 lar  bed  filtration, foam scrubbing, and several  types
 of  steam  or high-pressure water ejector scrubbers.
 Entirely new concepts utilizing new mechanisms have
 the potential for providing high-efficiency fine  parti-
 cle  collection  or  for  permitting   the  growth  of
 particles by agglomeration for subsequent more effici-
 ent collection. New concepts that have been advanced
 include  charged  droplet scrubbing and collection  of
 charged  particles by fiber beds.
    All  known  novel  devices  and  new  collection
 concepts are being reviewed by EPA. Those  showing
 potential for fine particle collection will  be evaluated
 for  performance and related  cost. Systems  showing
 promise of high-efficiency fine particle collection at
 reasonable  cost  and meriting further development
 will, if necessary, be further supported by  CSL.

   Wet Scrubbing—\n a wet scrubber, both gaseous
 and particulate pollutants are transferred from the gas
 to  the  scrubbing liquid.  The  availability  of  a wide
 variety of scrubber types and scrubbing  liquids gives
 wet scrubbers the potential for satisfactorily  remov-
 ing many pollutants.
 Sulfur Oxides Control

   In  the  area  of  sulfur  oxides  (SOX)  control,
 achievement of Ambient Air Qi  ;lity Standards de-
 mands the  control of  industrial combustion,  indus-
 trial processes, ana area sources,  as well as  utility
combustion.  Natural low-sulfur fuels are only suffici-
ent to  satisfy about  40 percent of the demands of
State Implementation  Plans. The remainder must be
supplied  by  control  technology  in  the  form  of
effluent desulfurization,  fuel  cleaning,  or  process
modification. Although  the currently  defined  SOX
control technology program contains developmental
projects of sufficient  diversity to ensure the achieve-
ment of Ambient Air  Quality Standards, a substantial
EPA  research and  development  investment  will  be
required to  bring  this  technology to  commercial
fruition. Only in the  case of effluent desulfurization
technology for  electric utility applications will  the
control technology achieve  widespread  commerciali-
zation within the next few years.
   Consistent with Congressional  guidelines,  CSL's
major  concern has  been the control of sulfur oxides
from  fuel  combustion.  About  80  percent  of the
Laboratory's  total  expenditures to date  have been in
this  area  and have been concentrated on  flue  gas
cleaning. Flue  gas  cleaning  devices are now being
installed on commercial power plants in this country.
The  prototype demonstrations that  CSL has under-
way  are shown  in Table 15. Except for clean fuels,
flue gas cleaning is probably the only  sulfur oxides
control technique  that will have widespread applica-
tion  within  the next  10  to  15  years. With  the
expected shortage of clean fuels (amounting to about
Table 15. PRESENT AND PROJECTED FLUE GAS
         CLEANING DEMONSTRATIONS
Process and
application
Wet limestone
scrubbing
Shawnee-
TVA (30
MW, coal)
Key West
(40 MW, oil)
MgO scrub-
bing (Chemi-
cal: 155
MW, oil)
Cat-OX (Mon-
santo: 100
MW, coal)
Wellman-Lord
(115MW,
coal)
Stone & Web-
ster/Ionics
(70 MW,
coal)
Startup
April 1972
January 1974
May 1972
June 1972
July 1975
November 1975
Removal
efficiency, %
75-90
60-80
85-90
85-90
90-95
90-97
Control Systems Laboratory
                                              123

-------
Wet limestone scrubbing system for sulfur dioxide removal is in operation at TVA's Shawnee coal-fired power
plant in Paducah, Ky.
20  percent  of  the  coal  demand), flue gas cleaning
should find wide application.
   The need to develop techniques to permit the use
of eastern and midwestern coal is shown clearly in the
accompanying figure. Only about 7 percent of this
coal is usable under New Source Performance Stand-
ards.  Because of physical and contractual  limitations
it is not possible to mine all the low sulfur coal first.
(That is, the mining will  proceed from left to right,
not  from bottom to  top.) Thus  a  native  resource
approximating the GNP will not be available for use if
cleaning  techniques  are  not utilized. It  had  been
projected that this would cause economic dislocations
and  unemployment,  substantial  increase in  the flow
of dollars outside the country, and increased depend-
ence of the security of our country on mid-eastern
oil; current events substantiate that projection.
13
-------
   2500
   2000
   1500
   1000
    500
 ESSENTIALLY ALL KNOWN RESERVES
 MADE AVAILABLE BY 95% EFFICIENT
 FLUE GAS CLEANING PROCESSES
 (EXAMPLES:  SODIUM ION SCRUB-
 BING WITH THERMAL REGENERA-
 TION, AND SODIUM HYDROXIDE
 SCRUBBING WITH ELECTROLYTIC
 REGENERATION)
ADDITIONAL RESERVES (TO 2.5% S)
MEETING NSPS MADE AVAILABLE BY
75% EFFICIENT FLUE GAS SCRUBBING
PROCESSES NOW BECOMING COMMER-
CIALLY AVAILABLE (EXAMPLE: WET
LIMESTONE SCRUBBING)
            NATURALLY OCCURRING LOW-
            SULFUR COAL (<0.7%S) THAT MEETS
            NSPS
 Value of eastern and central coals meeting new source
performance standards as a function of efficiency of
flue gas cleaning processes (value of coal resources at
$4 per ton).
and  cleaning, and  pollutant control  evaluation  and
optimization. The  most recent work  is  aimed at
chemical desulfurization of coal and the problems of
hazardous pollutants in fossil fuel.
   Two  factors—the major contribution of small coal-
and oil-burning sources  (area sources) to the degrada-
tion  of  ambient  air quality and the severely  limited
supplies of low-sulfur fuels—indicate a need for clean
fuel  or  coal conversion  processes. CSL has provided
funds to both the Bureau of Mines and the Office of
Coal Research to assist  in both the development of
conversion and gasification processes that can provide
clean fuels and the determination  of environmental
controls that will be required for these techniques.
   Since   1967,  CSL  has  been  actively  developing
several  versions  of  the fluidized-bed  process  for
combustion of coal  and residual oil as a means of
economical pollution control in  low cost steam and
power generation. This combustion process has the
capability of reducing pollutant emissions 95 percent
for S02,  80  percent  for NOX,  and 99 percent  for
particulates. In addition, the capital costs for such a
plant  would   be  10  to  20  percent  less  than a
conventional facility, and thermal discharge to water-
courses can  be  reduced   by  10  to  60  percent.
Fluidized-bed  combustion  represents  an  attractive
long-range solution to the control of pollutants from
utility boilers.
   The Laboratory  is also conducting  research into
the control of  emissions from smelters, iron  and steel
operations, kraft wood pulping mills, iron foundries,
secondary  aluminum furnaces, and other industrial
sources of SOX.
Nitrogen Oxides Control

   On a National basis, 65 percent of the emissions of
nitrogen oxides (NOX)  are from combustion sources
other than  motor vehicles.  For this reason, the CSL
program  is  oriented  heavily  in  the direction  of
combustion control. Control of stationary sources of
NOX will be necessary for achieving and maintaining
Ambient Air  Quality Standards  as  well as for estab-
lishing future  New Source Performance Standards.
   The main  approach  has been modification of the
combustion   process to  reduce  NOX  formation.
Bench-scale  work  and  field testing  indicate  that
necessary control for the immediate future can  be
achieved  by  this  method.  In  addition,  stack  gas
cleaning processes  are  being evaluated and  investi-
gated on a  small scale;  results in this area, however,
are not encouraging thus far.
   A further complication in nitrogen oxides forma-
tion  is that not only is  nitrogen fixed in the air, but
also  some  fuel  nitrogen  is converted  to  nitrogen
oxides. Some  success in controlling NOX  from fuel
nitrogen has been achieved, however. Whether control
of fuel  nitrogen by combustion  modification alone
will be adequate has not yet been determined.
   The accompanying  figure shows  another area  in
which CSL has made a  major contribution—nitrogen
oxides control in coal combustion, the most difficult
area.  The  field  testing  program,  which  has been
underway since the beginning of calendar year 1971,
has  been  more  effective than   anticipated and  is
substantially ahead of  schedule.  The second part  of
Control Systems Laboratory
                                                                                      125

-------
NOX CONCENTRATION (ppm, 3% 02 DRY)
M A O) OO 0
0 0 0 0 0
O 0 0 O 0 0
t>
*£*?•
L
\ \
,S * ^ PROJECTED
\4 *- -AHTIIAI (RESULTS OF FIELD TFSTINfi)
FIELD TESTING (700 ppm"'---...
5
i
^^^ "\
O x —
\
Vy NSPS (525 ppm)
X
ENGINEERING R&D (300 ppm) *>**-- ^^
'
FUNDAMENTAL COMBUSTION RESEARCH (150 ppm) ^17;
k
1
        1969
70
          71
72        73        74        75
                                                          76
                                                                                         77       1978
                                                CALENDAR YEAR
Control of nitrogen oxide emissions from coal-fired utility boilers.
the NOX program, engineering research and develop-
ment  began in  calendar year 1974 and is expected to
furnish  technology  permitting  the attainment  of
National New Source Performance Standards by the
beginning of calendar year 1975. It should ultimately
allow  the attainment of average emissions of less than
300 ppm of NOX.
   The  basic research, which  got underway at the
beginning  of calendar  year  1974,  is expected  to
provide technology  to  allow  average  emissions  of
150 ppm NOX to be obtained in 1978.
   Primary efforts during Fiscal Year 1974 will be the
development  and demonstration of  modified operat-
ing procedures  for NOX  control on pilot- and  com-
mercial-scale  boilers. The efforts of the  overall  com-
bustion  research  and  development  program  are
classified under  the main areas of fundamental studies,
fuels research and development, process  research and
development, and field testing.

   Fundamental Studies—A number of projects classi-
fied as fundamental  research  studies are directed at
providing  a  basic understanding of the  important
phenomena involved in  the formation and destruction
of pollutants during the combustion process. This
understanding can then be used to improve existing
combustion  control techniques and to suggest other
techniques with even greater  promise for control of
                                 pollutants.  The  fundamental  studies  cover  three
                                 categories of work: the chemistry of pollutant forma-
                                 tion and destruction, the physical processes of com-
                                 bustion, and the mathematical simulation of combus-
                                 tion.
                                    The  actual conditions existing within the flame
                                 zone  are  a  function  of  the  physical  processes  of
                                 combustion. Most  combustors operate with diffusion
                                 flames where fuel  and air are introduced separately
                                 and mixing is dependent on the  manner of introduc-
                                 tion.  Because the flame zone is not of homogeneous
                                 composition, it is necessary to understand the role of
                                 combustion aerodynamics in pollutant formation. A
                                 contract with United Aircraft Research Laboratories
                                 has as  its  objective  the  establishment  by detailed
                                 velocity  mapping  of  the  flow-field  properties  in  an
                                 idealized  single-burner  combustor  as a function  of
                                 fuel and air inlet parameters. The local chemical com-
                                 positions  and the  exhaust product composition will
                                 be monitored to show the effect of aerodynamic and
                                 mixing  conditions. Future work  in this area will  in-
                                 clude a study of  the role of  flame interactions in
                                 multiple-burner systems on the emission properties of
                                 the systems.
                                    Because the chemical and physical effects of actual
                                 combustion  are closely related,  it is essential to pro-
                                 vide a  method of tying  these  effects  together and
                                 generalizing  the  results  for a  variety of  systems.
126
                                                       ANNUAL REPORT 1973

-------
          •
  *•  ^'^
             i
Catalytic oxidation process for sulfur dioxide removal is in operation at Wood River Power Station in A /ton, IL.
 Mathematical simulation of combustion by modeling
 is the tool  used  for this purpose. In the past year,
 work has been directed toward developing the neces-
 sary components  of the model. Major effort has been
 expended in the development of a rapid computerized
 technique to allow evaluation of combustion kinetics
 of numerous simultaneous reactions,  incorporation in
 the model  of simplified flow fields,  improvement of
 the turbulence model,  and comparison of model pre-
 dictions with cold- and  hot-flow furnace data using
 simple chemical kinetics. Ultimately, the kinetics and
 fluid-flow programs must be  applied  together to give
 a realistic description of any practical system.

   Fuels  Research and  Development-Fuels research
and development studies are  conducted  on versatile
experimental combustion systems. The studies are de-
signed  to develop  generalized combustion control
technology that is applicable to the control of NOX
and other combustion-related pollutants  from con-
ventional fuels, waste fuels, and future fuels. Studies
conducted  to date have  been designed  to develop
combustion  control  technology  for  a specific  fuel
through single-burner design  criteria on combustion
modification  techniques.  These  studies provide the
future  goals for NOX control and will generate the
necessary  technology to  be  applied  in the process
research and development area.
   Contracted studies with the Institute of Gas Tech-
nology (IGT) have been directed toward the relation-
ship between combustion, aerodynamics,  and  pollu-
tant emission characteristics  of industrial gas burners.
A  recently initiated study with IGT will further inves-
tigate  specific  burner and  process  parameters  and
Control Systems Laboratory
                                              127

-------
Wet limestone (coral) scrubbing system for sulfur dioxide removal is in operation at oil-fired power plant in Key
West, FL.
evaluate and optimize burner design to minimize NOX
emissions from natural gas firing. A new experimental
furnace has been  built for this program. The detailed
experimental  program will evaluate  three classes of
industrial gas burners. Detailed in-the-flame probing
will  be conducted to better  understand the  role of
aerodynamics in pollutant formation. The experimen-
tal  program and  final report  are scheduled for com-
pletion late in 1974.
   The International Flame Research Foundation  is
under contract to develop combustion system design
criteria for heavy  oil-  and coal-fired furnaces.  Two
series of  experimental  trials have been conducted to
relate burner design parameters  to  pollutant emis-
sions, flame  configuration, and  combustion effici-
ency. These  trials  have  consisted  of input/output
measurements followed by detailed flame probing for
a  limited number  of  cases. Results to  date  have
                                                                           ANNUAL  REPORT 1973

-------
identified  the types of flow conditions required to
control formation of NOX from pulverized coal.


   Process Research and Development—CSL's process
research and development work involves studies with
commercial  and prototype  combustion  systems  for
the application of optimum  NOX control technology.
Results of these studies will  provide the basis for the
demonstration of combustion control technology. To
date,  the  studies  have considered ail  conventional
fuels and combustion systems. The major emphasis,
however, is  in controlling IMOX emissions from coal-
fired utility boilers.
   Two  major  programs that  will have  significant
beneficial  impact  are  those related to  combustion
modifications  of a  125-MW,  tangentially coal-fired
utility  boiler (Combustion  Engineering, Inc.) and a
125-MW, wall  coal-fired  utility   boiler  (Tennessee
Valley Authority). Both programs will evaluate staged
combustion  as a control technique for  NOX with
special emphasis on unit  performance  and  fire-side
corrosion.
ing 60  to  70 percent were  achieved  with gas-fired
units, and 50  to 60 percent with  oil-fired units:
initially, reductions with coal-fired  units were not as
successful.  NOX  reductions on the  gas- and oil-fired
units were  primarily  achieved  through  low-excess-air-
firing and  staged  combustion. In  the  past 2 years,
emphasis has been placed on  coal-fired boilers.  Esso
was  recently able to reduce  NOX  emissions by  an
average  of  40 to 50  percent by using low excess  air
and staged  combustion on 12 coal-fired units without
increasing other omissions or significantly affecting
boiler  performance.   However, more information  is
needed to determine the effect of combustion modifi-
cation with coal-fired units and tube-wall  corrosion.
   In the future, new burner designs will be tested in
industrial  and  utility boilers,  and testing  will  be
conducted  on  such  techniques as  increasing fuel
richness during staging of combustion. The effect  on
emissions  of mixed-fuel  firing and fossil-fuel/waste-
fuel  firing will  be determined. Also, the effect  of
firing coal-derived fuels,  such  as low-Btu gas, will  be
investigated.
   Field Testing-CSL has sponsored several field test
programs, with  boilers  ranging  from  residential to
utility size, to determine what can presently be done
to control NOX and combustible emissions. This work
is  done on  commercial equipment and  is generally
performed  by research  and  development organiza-
tions familiar with the  specific combustion systems
being studied using the financial  and technical assist-
ance of manufacturers,  users, and trade associations.
In  addition  to   developing  trends  and  providing
directional  recommendations for industry to  use to
minimize  emissions  with  today's  technology, the
work also defines where  the  research and  develop-
ment efforts should  be concentrated by  developing
emission  factors  as a  function of equipment type and
size, and  fuel consumed. The field testing studies are
the  initial   efforts in  the development  of  control
technology and  are designed to  provide the state-of-
the-art in control of  NOX and combustible emissions
from existing commercial combustion systems.
   A study with  residential (up to 30,000 Btu/hr) and
commercial  (300,000 to 10,000,000  Btu/hr)  boilers
was  jointly  sponsored  by the American Petroleum
Institute  (API)  and  EPA.  Battelle  Laboratories, the
contractor,  concluded that emissions  from  this size
range of  equipment can be controlled best by proper
burner design and proper maintenance.
   Field  tests with utility (500,000,000 Btu/hr and
greater)  boilers  have been performed  by Esso Re-
search  and  Engineering  Co.  During  1971,  the first
year of the tests, 17 boilers (25 boiler/fuel combina-
tions)  that  fired coal,  oil, and/or gas were  tested.
Depending on boiler design, NOX reductions  averag-
   NOX  Program  Summary—Jo date, it has  been
shown:  that flue gas  recirculation is the  most effec-
tive combustion control technique for NOX emission
from  nitrogen fixation of atmospheric nitrogen, and
that staged combustion is the most  effective control
method for NOX emissions from fuel nitrogen conver-
sion. The development of this technology by the EPA
has allowed  the control of  NOX emission from gas-
and  oil-fired  utility  boilers to  a  level  of  150 to
250 ppm. In short-term testing, combustion modifica-
tions  have also resulted in  NOX  reductions of up to
50  percent in  commercial  coal-fired  utility boilers. In
addition,  burner and  furnace  design  variables have
been  shown  to cause widely  varying NOX emission
levels  in  all   boiler categories. Current  efforts are
directed  toward  the continued  development  and
demonstration of  modified  operating  procedures for
NOX  control  in  pilot- and commercial-scale  utility
and industrial boilers. Future work will support the
establishment of New Source Performance Standards
by applying the control technologies,  developed as a
result  of this research and development effort, to
pilot- and commercial-scale demonstration of com-
bustion control of NOX for  existing and new combus-
tion sources   in all size  categories.  In addition, the
research and development effort will be extended to
develop control technology  applicable to the combus-
tion of additional  fuel types  (including coal-derived
fuels such as low-Btu gas,  mixed fuels, waste  fuels,
and methanol)  and covering  a wider range  of com-
bustion  equipment  (e.g.,  stationary  gas  turbines,
internal combustion  engines,  and  industrial  process
furnaces).
Control Systems Laboratory
                                               129

-------
Hazardous and Other

Pollutant Control

   As EPA's regulatory program  has  developed, the
number of pollutants requiring control has expanded
to include more than 30 potentially hazardous and/or
annoying  air pollutants. The overall goal  relating to
hazardous  and other  (other  than SOX,  NOX, and
particulates) pollutants involves demonstration of the
"best" technology for controlling pollutant emissions
from  specific combustion  and industrial processes to
such a degree that a net health benefit is realized with
the least  economic  impact.  Established technology
can lead to setting New Source Performance Stand-
ards or Hazardous Emissions Standards.
   Each of several hundred different industrial source
types has  a different degree of adverse environmental
impact.  The  data  base describing many of  these
source types is either non-existent or not in a form
suitable for deciding  on the need to develop control
technology for the sources. A major effort is under-
way in CSL to generate the needed data base so that
the  environmental  impact of the  sources  can be
assessed accurately. Where  currently installed control
technology does not reduce emissions sufficiently for
them  to  be  of  insignificant environmental  impact,
control  technology must be  developed. All opti-ons,
including  add-on  devices,  process changes, and raw
materials  changes,  are  considered in selecting the
most  attractive   approach  for technology  develop-
ment. The programs in the  "hazardous' element then
involve either source assessment or technology devel-
opment.
      The goal  of CSL's highly source-oriented con-
trol program for hazardous and other pollutants is to
control  all   pollutants  from a  given  source.  For
convenience  in presentation,  the  extremely diverse
program  can be  divided into six  source  categories:
organic  chemical  processes, inorganic chemical  proc-
esses, ferrous metals processes,  non-ferrous metals
processes, open   sources,  and  hazardous  pollutants
from combustion  sources.
   Organic Chemical Processes—In the area of organic
chemical processes, CSL has three source characteri-
zation  (assessment) programs underway: acrylonitrile
manufacture, petrochemical  flares, and  hexachloro-
benzene  sources.  The  Laboratory  also  has four
technology development programs underway  involv-
ing:  catalyst  regenerators  at  refineries, pulp  mill
recovery furnaces,  rendering  plants (odor control),
and  ethylene dichloride  plants.  Projects are  also
underway to assess the economics of various sulfur
control options at petroleum refineries.
   Inorganic  Chemical Processes—Relating to  CSL's
work with  inorganic chemical processes, a program is
underway to determine the need to develop control
technology for fluoride emissions from gypsum ponds
at fertilizer  plants.  Another  ongoing  project  will
provide data to quantify the  capability of control
equipment for  enclosed asbestos sources: hopefully,
this  data  will be used to strengthen the equipment
standards for asbestos control.

   Ferrous Metals Processes—The  ferrous metals in-
dustry  converts iron ore  and scrap iron  into  useful
iron  and  steel   products. At large integrated  steel
plants,  iron ore, limestone, and coke are charged to a
blast furnace where the iron ore is reduced to molten
metal,  which is periodically tapped. The iron  from
the blast furnace is saturated with  carbon that  must
be removed to  change it into steel. The iron  from the
blast furnace, usually molten, is generally mixed with
cold  scrap  in a  steelmaking furnace where it is blown
with air  or  oxygen, which  burns the carbon,  to
produce  steel.  It  is  in  the  steel  furnace  that the
carbon level is  reduced to the required level, impuri-
ties  are  removed,  and alloying agents are  added.
(Other, less important, steel-making furnaces are the
open-hearth and the electric arc.) The steel from the
furnace is poured into ingots that solidify. The ingots
are then adjusted to proper and uniform temperature
and  physically  squeezed  into  the  desired  shape in
rolling  mills.
   This sounds  simple, but  in reality  it  is  rather
complex as there  are many ancillary processes and
operations  to  contend  with;  e.g.,  sintering,  coke
production, scarfing, and galvanizing.
   The iron and steel industry is not limited to  large
integrated  plants: small iron and steel  foundries are
spread  throughout  the  country.  In these foundries
scrap  iron  or  steel  is  melted  in  electric  arc  and
induction  furnaces  or in  cupolas with  little  or  no
refining, then poured into molds to solidify into the
desired shape.
   Production of coke in conventional oven batteries
has traditionally been a  major source of particulates,
SOX, odors, carcinogens, and hazardous trace metals.
It has  been shown  that top-side coke oven workers
have a substantially  higher risk  of  lung cancer than
the  average  worker,  probably  from carcinogenic
materials associated  with  the  particulate fraction of
the emissions.  Until  recently, emissions from  this
source  have been relatively uncontrolled. Because the
majority of  existing cokemaking  facilities will  be
operable for the next  25 years and because  most
facilities  built  in   the  next  10 years  will feature
conventional  oven batteries, CSL has  had to concern
itself with  developing control  technology for conven-
tional  batteries  in  order  to  meet  pollution control
guidelines until  the end of the century.
                                                                            ANNUAL REPORT 1973

-------
   Present indications are that, even though pollution
control  technology  may be developed  for  conven-
tional batteries, equipment will probably be expen-
sive and have high-maintenance cost, yet may not be
able to control  all pollutants. The expected long-term
solution to the coking problem is a continuous coking
process  that emits pollutants  in a more  controllable
form. CSL's involvement   in  coking  is ultimately
expected to encompass continuous cokemaking.
   Specific coke oven emission control projects with
CSL involvement include:  smokeless coke charging,
enclosed coke pushing and quenching, smokeless coke
pushing, and  improved  coke  oven door  seals.  As
shown in  the accompanying figure, CSL's prototype
demonstrations are  expected to permit reduction of
coke  oven emissions from coke production, CSL is
now  expanding its  outlook-initiating  projects  in
other areas  of the  industry,  in  addition to coke-
making. Other  major CSL  ferrous emission  control
projects are  related to sinter plant windboxes, basic
oxygen  process (BOP)  furnaces,  and  iron  foundry
cupolas.

   Non-Ferrous  Metals  Processes—CSL's  activities
relating  to non-ferrous metals processes—particularly
relating  to air  pollution problems  associated with
primary  copper,  lead, and zinc production  in  the
U.S.—began  late  in  1967  with a  survey  of sulfur
oxides  and   particulate  matter  emitted  by those
industries. The  study by Arthur G.  McKee and  Co.,
completed early in  1970,  gave a general qualitative
and quantitative status of  emissions in the smelting
industry.
   The  "McKee"  effort was followed  by  another
general  study—this one  to  appraise the suitability of
Monsanto's  Cat-Ox  process  and  the  Well man-Lord
process  for  controlling sulfur oxide emissions from
copper,   lead,  and  zinc  smelters.   The  study   was
performed by Stanford Research Institute.
   Because U.S. copper smelting exposes a significant
segment  of  the population  to  a multiplicity  of
pollutants whose effects have not  yet  been deter-
mined,  efforts  are  underway to  evaluate emissions
from  such  plants.  CSL has also  initiated  a set of
development projects.  Two  new  efforts currently
being mounted  have as their respective objectives:

   •  Providing  smelter-by-smelter  information  to
      EPA on the optimum application  of currently
      demonstrated  technology   to  simultaneously
      control all smelter streams containing S02  and
      particulates. The  output will be  in the form
      currently  being  accepted  by  the  courts as
      demonstration  by  means of technology trans-
      fer.
   •  Assessing the  environmental considerations of
      emerging technology for metal-winning in the
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      primary  non-ferrous  industry. In this  project,
      consideration will be given to hydrometallurgy
      as a new smelting process.

   CSL and Phelps Dodge Corporation started a cost
 sharing study  in  July  1971  on a new SOX  control
 method  based  on  reacting  the  S02 with  h^O, with
 sulfur values   recovered  as  elemental  sulfur. Initial
 attempts to generate  the  needed  H2S  by  roasting
 available  copper  ore with  steam at 800°C  showed
 that, although  it was technically feasible, the econom-
 ics were prohibitive. The emphasis has now shifted to
 leaching  the   concentrate  with hydrochloric  acid,
 which decomposes the  pyrite and/or pychloric in the
 concentrate  and  releases ample quantities of  h^S.

 Preliminary results are promising; however, tests are
 required to understand  the observed  variations in h^S
 generation as a function of the concentrate source.
   EPA  has entered into two separate Public Law 480
 Agreements  (excess foreign currency program) with
 Yugoslavia: one with the Institute for Copper, in Bor;
 and  the  other with the Lead  and  Zinc Institute in
 Trepca.  The  Bor project  is  a  3-year investigation
 (begun  in May   1971)  being  carried  out at  an
 American-engineered copper smelter,  the  largest in
 Europe. The Trepca project is a similar 3-year effort
 (started in October 1971) being carried out at a lead
 and zinc smelter.
    Objectives of both projects are:

    •  To  characterize,  quantitatively  and  quali-
       tatively, all air  pollutant emissions  from  this
       type of smelter.
Control Systems Laboratory
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   • To relate air pollutant emissions to the smelter
     feed and to feed changes so that data will apply
     to other smelters.
   • To relate air pollutant emissions to operational
     changes (changes  in smelter configuration) so
     that data will apply to other smelters.
   • To determine the effects of controlling  sulfur
     dioxide and  particulates on the emission of all
     other pollutants,  especially of the  "hazardous"
     heavy metals.

The  relationships  that are  being  developed  in these
two  Public  Law 480  projects are  expected  to be
applicable to the  domestic  non-ferrous smelting in-
dustry.
   CLS's interest  in hazardous and  other emissions
from  the non-ferrous  metals industry  prompted a
study being performed at the South Dakota School of
Mining under a research grant. The hazardous element
of  interest in this study  is the mercury  vapor or
metallic mercury found in smelter or power plant flue
gases.
   Another  CSL-funded  effort relating to  mercury
and  other hazardous  pollutants  (e.g.,  arsenic,  cad-
mium, selenium,  antimony,  beryllium, copper, zinc,
and lead) is a study by Monsanto Research Company
to  ascertain   concentrations  of  these  metals in
smelter-produced  sulfuric  acid.  Such  a  survey  is
intended  to  help predict  the  fate of  hazardous
pollutants produced by smelter sulfuric acid  distribu-
tion to, and consumption by, different industries.

   Open  Sources—CSL's  open sources program  is a
broad-based  source characterization program,  initi-
ated  to   characterize  all  major  sources  of  toxic
emissions from  mining and materials handling  opera-
tions for the metallic ores and non-metallic  minerals
industries. Studies are  underway: to identify hereto-
fore unrecognized  major sources of asbestos;  to assess
the importance of and develop control technology for
asbestos  mining sites; and to assess the importance of
and develop  control techniques for industrial wastes
containing asbestos.

   Hazardous Pollutants from Combustion Sources—
CSL's  program relating to  the control  of hazardous
pollutants from  combustion  sources is  closely coor-
dinated  with the  Laboratory's   particulate control,
NOX  combustion,  and  SOX  flue gas cleaning  pro-
grams. Because the initial emphasis is upon characteri-
zation of emissions from the most significant sources
of  pollution, the  approach  of the program  is  similar
to that for industrial process control programs.
   Coal-fired  utility and industrial  boilers  were se-
lected  as being of highest priority. Midwest Research,
selected  as   the   contractor  to  characterize  these
sources  for  hazardous  emissions, has  developed a
comprehensive  test program covering  all significant
parameters that might  affect toxic pollutant emis-
sions. The program was prepared  during 1973 with
actual sampling beginning early in 1974.
   In  addition to the characterization  of utility and
industrial   boilers,  studies  are  being  initiated   to
identify  control  alternatives for  open  combustion
sources.
 Energy Research and

Development


   A  major effort has been underway since July 1973
to develop a  plan  for increased Federal  support of
energy  research and  development. As  noted in  the
special  Energy and the Environment section  of  this
Report, the Control Systems Laboratory has provided
substantial support to this planning activity and is
expected  to assume a major role in  the implementa-
tion  of the new energy  programs.  The  accelerated
development of new energy processes will  require an
extensive   technology assessment  function  within
EPA.
   The  expanded control  technology  research  and
development program  will require increased budgets
for EPA starting in Fiscal Year 1975. CSL  is expected
to assume the  lead  in  managing  these  funds;  the
program  will  be implemented  through interagency
agreements and activities conducted by  other EPA
laboratories that are coordinated by CSL, as  well as
through direct contracts to the private sector.
   The  significance to EPA  of  this energy research
and development function cannot be  overemphasized.
During  the next  5 years, decisions will  be made  and
technology will  be  developed that will  firmly estab-
lish the basis for the generation of energy for decades
to come.  These new energy technologies must be
environmentally  sound  if  the  future  health   and
welfare of the Nation is  to be  protected. Although
environmental  considerations  may be subjugated to
short-term energy needs,  there must ultimately be a
reconciliation  of energy and environmental considera-
tions.
   Active  involvement  by  EPA will  ensure   that
environmental  control systems  keep pace with  new
energy processes.
132
                     ANNUAL  REPORT  1973

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