FINAL REPORT
on
POTENTIALLY TOXIC AND HAZARDOUS SUBSTANCES
IN THE INDUSTRIAL ORGANIC CHEMICALS AND
ORGANIC DYES AND PIGMENTS INDUSTRIES
to
U. S. ENVIRONMENTAL PROTECTION AGENCY
IERL, CINCINNATI, OHIO
October 30, 1976
by
R. A. Markle, A. F. Fentiman,
T. R. Steadman, and R. A. Mayer
Contract No. 68-02-1323
Task No. 56
BATTELLE
Columbus Laboratories
505 King Avenue
Columbus, Ohio 43201
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Columbus Laboratories
505 King Avenue
December 29, 1976 Columbus. Ohio-43201
Telephone < t>14» 424-b424
Telex 24-5454
Dr. Leo Weitzman
Industrial Environmental Research Laboratory
U.S. Environmental Protection Agency
5555 Ridge Avenue
Cincinnati, Ohio 45213
Dear Dr. Weitzman:
Task 56, Contract Mo. 68-02-1323
The extensive modification and editing required to prepare a Task 56 report
suitable for publication has now been completed and the final report is
enclosed. The reproducible master copy is for your use in preparing additional
copies of the report as required. The originals of the oversize master tables
and the magnetic cards containing the text and most of the extraction tables
are being mailed under separate cover.
If you have any further questions or comments, please call me. I have enjoyed
working with you in preparing this timely document and have greatly appreciated
your guidance during its preparation and revision.
Sincerely yours,
O
Richard A. Markle
Task Leader
RAM/jph
Enclosure
cc: Mr. M. P. Huneycutt
Mr. J. McSorley
Control Systems Laboratory
U.S. Environmental Protection Agency
Research Triangle Park
North Carolina 27711
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ABSTRACT
The objectives of this research program were the identification
of the potential hazards associated with the production and utilization
of industrial organic chemicals (IOC) and organic dyes and pigments
(ODP) and the determination of the state of the art of the technology
for the treatment and control of potentially hazardous wastes generated
during the manufacture and use of these materials. The major output
of the study consists of comprehensive master tables of 511 IOC, 115 ODP
raw materials, 722 ODP intermediates and 1458 dyes and pigments, containing
correlated compound identifications, toxicity data, chemical production
process information, waste product information, production volumes and
end use information where available.
Work done to establish definitive criteria for prioritizing the IOC
and ODP according to toxic hazard produced a substantial set of potential
criteria. However eighteen "prioritized" lists that x^ere actually produced
were based solely on the various types of toxicity data, and the production
volume data, contained in the master tables.. Eight of these tables were
assembled with the chemicals ranked in order of quantitative toxicity
or production volume data and can be viewed as "priority rating" lists.
The compounds in the remaining nine tables are presented alphabetically
and can be considered useful "priority" groups. These tables identify
some of the chemicals that pose the greatest potential hazards. However,
because the availability of specific data types on individual compounds
is limited, these tables are all incomplete compilations. For example
the most prevalent single data type, acute oral data on rats (LD50, oral-
rat), is available on about 50 percent of the IOC. The other data types
are available on 39 percent to one percent or less of the IOC, and 20
percent, or less of the ODP. Although a total of about 150 of the IOC
on these various lists appear to pose potential toxic hazards, the toxicolog-
ical data, taken from secondary compendia, were shown to range widely
in precision where replicate data were available. Consequently these
simple "prioritized" lists must be used with caution. Comparison of seven
of these "prioritized" lists with four EPA priority lists produced 46
IOC of possible special significance in terms of hazard potential common
to the two sets of priority lists. Because of the complexity of these
industries and the present state of toxicological data availability and
understanding, this study should be viewed as a beginning effort.
Assessment of the state of the art of pollution control and waste
treatment technology showed that most of the published information is
of a general nature. It was not possible to specify "best" technologies
for particular chemicals/processes given the broad scope and the time
and funding available for this study.
iv
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CONTENTS
Foreword iii
Abstract iv
Tables viii
Acknowledgment xi
1. Executive Summary 1
2. Introduction 7
3. Objectives 10
4. IOC and ODP Industry Comparisons. 12
5. Research Approach 13
6. Master Table Compilation 15
Information Included in Master Tables 15
Name and Formula 17
Identifying Symbols 17
Toxicity Data 17
Acute Toxicity Data 17
Chronic Toxicity Data 18
Additional Background on the Toxicity Data 19
TLV . 19
Compound, Process, and Waste Data 19
Total Production Volumes 19
Uses 20
Data Availability ..... 20
Industrial Organic Chemicals 20
Organic Dyes and Pigments 21
Toxicity Data - IOC 22
Quantitative Human Toxicity Data 22
Carcinogenic, Teratogenic and Mutagenic Data 22
Quantitative Oral Toxicity 22
Quantitative Inhalation Toxicity 23
Additional Quantitative Toxicity Values 23
IOC (Table A-l) Summary 23
Toxicity Data - IOC Addendum 24
IOC Toxicity Data - Overall Summary 24
Toxicity Data - ODP 24
ODP Raw Materials and Intermediates 24
ODP - Dyes and Pigments 25
ODP Toxicity Data Summary 25
Process Data 25
Waste Stream Data 25
Production Volumes 25
7. Data Extraction Tables 27
IOC Extraction Tables 27
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U.S. Occupational Standard (USDS) for Concentrations in Air-
Industrial Organic Chemicals Listed Alphabetically
According to Compound (Table F-l) 27
USOS Standards Listed According to Increasing Standard
Concentrations (Table F-2) 27
Human Toxicity Data (Table F-3) 28
Carcinogens or Suspected Carcinogens (Table F-4) 28
Teratogens and Mutagens (Table F-5) 28
Oral Toxicity (LD50, Rat) (Table F-6) 29
Oral Toxicity (LD50, Animal Other Than Rat) (Table F-7) ... 30
Inhalation Toxicity (LC50) (Table F-9) 31
Mixed Toxicity Data (Table F-10) 32
Production Volume Data 32
ODP Extraction Tables 32
U.S. Occupational Standard (USOS) for Concentrations in Air
Organic Dyes and Pigments Listed Alphabetically According
to Compound (Table H-l) 32
Human Toxicity DataOrganic Dyes and Pigments (Table H-2). . 33
Carcinogens and Suspected CarcinogensOrganic Dyes and
Pigments (Table H~3) 33
Oral Toxicity (Rat)Organic Dyes and Pigments (Tables H-4,
H-5, and H-6) 33
8. Prioritization Schemes 34
Priority or Rating Lists 34
EPA Priority Lists 35
Comparison of This Study "Priority" Lists and EPA Priority Lists. 36
Comparison of U.S. Occupational Standards (USOS) with USSR
Workplace Standards 37
Preliminary Attempts to Establish Rating Criteria . 38.
Toxicity Data Pitfalls. . 38
Data Unavailability 39
Tentative Criteria for Use in the Identification and
Priority Listing of Hazardous Industrial Organic
Chemicals 39
9. Pollution Control Technology 43
Effluent Pollution Control Technology 43
Air Pollution Control Technology 44
Incineration 46
Adsorption 47
Absorption 47
Condensation 47
Inertial Separators 47
Wet Collection Devices 47
Baghouses 48
Electrostatic Precipitators 48 «
Other Collection Devices 48
10. Organic Dyes and Pigments Industry 50
Background . 50
Industry Characteristics 50
Hazardous Substances 50
Pollution Controls 51
Emissions Controls 51
vi
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Effluent Controls 52
11. Conclusions 54
12. Recommendations 58
References 61
Appendices
A. Industrial Organic Chemicals-Toxicity Production, Waste
and Use Data A-l
B. Organic Dyes and Pigments-Toxicity, Production, Waste,
and Use Data Associated with Dyes and Pigments and the
Raw Materials, Intermediates and Inorganic Chemicals
Used in Dye and Pigment Production B-l
C. Key to Abbreviations and Acronyms Used in Tables in
Appendices A and B C-l
D. References Used in Appendices A and B D-l
E. Industrial Organic Chemicals - Possible Additions to the
Master List E-l
F. Industrial Organic Chemicals - Extraction Tables Based on
Toxicity and Production Volume Data in Table A-l F-l
G. EPA Priority Lists G-l
H. Organic Dyes and Pigments - Extraction Tables Based on
Toxicity and Production Volume Data in Tables B-l through
B-3 H-l
I. USSR Maximum Allowable Concentrations of Harmful Compounds
in Working-Area and Inhabited Area Atmospheres I-l
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TABLES
Number . Page
A-l Industrial Organic Chemicals-Toxicity, Process, Waste, Produc-
tion and Use Data A-l
A-2 Industrial Organic Chemicals, Inorganics - Toxicity A-115
A-3 Industrial Organic Chemicals Addenum - Toxicity A-123
A-4 Emission Factors Not Listed in Table A-l A-135
B-l Organic Dyes and Pigments, Raw Materials - Toxicity Process,
Waste, Production and Use Data B-l
B-2 Organic Dyes and Pigments, Intermediates - Toxicity Process,
Waste, Production and Use Data B-5
B-3 Organic Dyes and Pigments - Toxicity Process, Waste, Production
and Data B"63
B-4 Organic Dyes and Pigments, Inorganics - Toxicity Process, Waste,
Production and Use Data B-175
C-l Key to Abbreviations and Acronyms C-l
D-l References Used in Appendices A and B D-l
E-l Radian List of Compounds to be Added to the List of Industrial
Organic Chemicals E-l
E-2 Industrial Organic Chemicals Not on the IOC List or on Table
E-l - from a 1975 Petrochemical Compilation E-2
E-3 1973 U.S. Tariff Commission Report Compounds Not Elsewhere
Listed. . . E-3
E-4 Additional Compounds to be Considered for Inclusion in IOC
Table A-l . E-4
E-5 Compounds Not Already Included Which Are Covered by Effluent
Limitations Guidelines Development Documents - Organic
Chemical Industry E-5
viii
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Number Page
E-6 Organic Chemicals in IPPEU-IOC but with No Process Number -
Possible Additions to the IOC List E-6
F-l U.S. Occupational Standard (USDS) for Concentrations in Air -
Industrial Organic Chemicals [Listed Alphabetically According
to Compound] F-l
F-2 U.S. Occupational Standard (USOS) for Concentrations in Air -
Industrial Organic Chemicals [Listed According to Increasing
Standard Concentrations] F-2
F-3 Human Toxicity Data - Industrial Organic Chemicals F-5
F-4 Carcinogens or Suspected Carcinogens - Industrial Organic
Chemicals F-7
F-5 Teratogens and Mutagens . Fr-9
F-6 Oral Toxicity (LD50, Oral-Rat) Versus Production Volume, Waste
and Carcinogen Data - IOC F-12
F-7 Oral Toxicity (LD 50, Animal Other Than Rat Values ^ 500 mg/kg)
Versus Production Volume, Waste and Carcinogen Data - IOC . . F-19
F-8 Oral Toxicity (LDLo, All Animals) Versus Production Volume,
Waste and Carcinogen Data - IOC F-20
F-9 Inhalation LC50 Data Versus Carcinogen, Production, and
Emission Data F-21
F-10 Toxicity Data ^ 500 mg/kg or ^ 1000 ppm Not Included in Tables
F-6 Through F-9 Any Animal or Administration Route .... F-23
F-ll Total Production - Industrial Organic Chemicals [Listed
Alphabetically According to Compound] F-25
F-12 Total Production - Industrial Organic Chemicals [Listed
According to Increasing Production for 1973] F-29
G-l Effluent Guidelines Priority List (IOC - Phase 1) G-l
G-2 Effluent Guidelines Priority List (IOC - Phase 2) G-2
G-3 Water Quality Planning and Standards Consent Decree List. . . . G-3
G-4 Potentially Significant Air Toxicants from the Office of Air
Quality Planning and Standards (AQPS) . . G-6
G-5 This Study "Priority" List IOC Distribution on EPA Priority
Lists G-7
ix
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Number Page
x>
G-6 List of Potentially Hazardous Waste Materials G-9
G-7 Spills List of Potentially Hazardous Substances G-14
H-l U.S. Occupational Standard (USDS) for Concentrations in Air -
Organic Dyes and Pigments H-l
H-2 Human Toxicity Data - Organic Dyes and Pigments H-2
H-3 Carcinogens and Suspected Carcinogens - Organic Dyes and
Pigments H-3
H-4 Oral Toxicity (Rat) - Organic Dyes and Pigments, Raw Materials. H-4
H-5 Oral Toxicity (Rat) - Organic Dyes and Pigments, Intermediates. H-5
H-6 Oral Toxicity (Rat) - Organic Dyes and Pigments, Dyes H-8
1-1 Comparison of United States and USSR Occupational Standards . . 1-1
1-2 Maximum Allowable Concentrations of Harmful Compounds in
Working-Area Atmosphere . 1-5
1-3 Maximum Allowable Concentrations of Harmful Substances in
Atmospheric Air of Inhabited Areas - USSR 1-13
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ACKNOWLEDGMENTS
The authors acknowledge the valuable assistance of the following persons
in assembling this report: Dr. Paul Spaite, EPA Consultant, for many val-
uable discussions concerning the philosophy and approach to the study based
on his association with the development of the "Industrial Process Profiles
for Environmental Use" and for bringing the existence of the USSR maximum
allowable concentrations (MAC) of chemicals in working - place and inhabited
area (Appendix I) atmospheres to our attention; Dr. Philip Leber, Battelle
Staff Toxicologist, for providing guidance in selecting and analyzing the
toxicity data; Mr. Daniel Dreyer, of the Battelle staff, for translating the
article on the Russian MAC data; and Dr. Leo Weitzman, EPA Project Monitor,
for providing excellent overall guidance in carrying out the study.
xi
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SECTION 1
EXECUTIVE SUMMARY
In view of the increasing concern created by rapidly expanding
industrial production of organic chemicals, and of federal toxic substances
legislation just enacted, the EPA has expanded studies of the organic
chemicals industry. Prior programs have usually been limited to studying
relatively small numbers of specially selected compounds or oriented
toward studying broad classes of pollutants such as BOD, COD, total
hydrocarbons, etc. A need exists for studies that will provide a comprehen-
sive and detailed data base covering the entire industry and the hundreds
of compounds produced by it. The present task was initiated as one
effort to satisfy this need by compiling information that would satisfy
the following two objectives:
(1) Identify the potential hazards associated with the
production and utilization of industrial organic
chemicals and organic dyes and pigments industries.
(2) Determine the state of the art of the technology for
the treatment and control of potentially hazardous
wastes generated during manufacture and use of these
materials.
The research followed to reach these objectives included the following:
Literature search and assessment of literature obtained
Compile master tables of toxicity, process, waste,
production volume and use data
Attempt to identify definitive criteria for prioritizing
the compounds according to relative hazard
Extract lists of compounds from the master tables
according to various specific types of toxicity
data, or production volume data. These lists can
be viewed as approximate "priority lists"
Acquire EPA priority lists and compare with this
study "priority lists"
Assess pollution treatment and control technology.
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In. the principal effort made to reach the objectives, a data base
has been assembled that will allow ongoing analysis of the hazard posed
by the production and utilization of industrial organic chemicals (IOC)
and of organic dyes and pigments (OOP) and their raw materials and intermed-
iates. The major output of the study consists of comprehensive master
tables listing 511 IOC, 115 ODP raw materials, 722 OOP intermediates and
1458 actual dyes and pigments. The tables contain the following correlated
information, where available:
Compound identification
Comprehensive toxicity data
Chemical production process information
Waste product information (quantitative data where available)
Production volumes
End uses (quantitative use patterns where available).
These master tables can therefore serve as convenient, single sources
of readily available, detailed information on specific compounds/processes,
or as guides to identifying and selecting groups of compounds for evaluation,
field study, effluent guidelines studies, new source performance standards
for air emissions and the like. They are also data pools useful in assem-
bling various data arrays specifically applicable to the analysis of toxic
hazard potential. As part of the present task a number of data extraction
tables were assembled, each keyed to a specific data type in the master
tables. Eighteen (18) different tables or lists of this type were assembled
based on the following types of data:
United States Occupational Standards (USOS)
Human exposure toxicity data (accidental exposure reports)
Carcinogenic data
Mutagenic and teratogenic data
Acute toxicity data
- Oral
- Inhalation
- Miscellaneous administration routes
9 Production volume data.
Eight of these data extraction tables contain the chief data type arranged
in ordered fashion (for example, in decreasing level of acute toxicity
value). Additional pertinent data, such as correlated carcinogenicity,
production volume and waste product data are also included in some of
the extraction tables. Individually these tables represent "priority
rating lists" of various types that are potentially useful in assessing
toxic hazard. It is important to note, however, that the variations in
data types represented on these individual lists make it impossible to
assemble a single, master list, of "prioritized IOC".
In a separate effort EPA priority lists developed prior to and independ-
ently of the present study were identified and obtained. Six of these
lists are presented in the report, with four of them, shown below, receiving
special attention.
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(1) Effluent Guidelines Priority List - Phase I Organics
(2) Effluent Guidelines Priority List - Phase II Organics
(3) Water Quality Planning and Standards Consent Decree
List (65 Toxic Pollutants List)
(4) Potentially Significant Air Toxicants from the Office
of Air Quality Planning and Standards (OAQPS).
These four EPA lists were first compared with the master lists of IOC
and ODP developed on this study, to show the overall commonality of compound
entrants (110 common out of 128 total entrants in the four EPA tables).
This is 86 percent commonality with most of the eighteen entrants not
in the IOC master lists being in categories that fall outside the scope
of the present study (plasticizers, insecticides, etc).
Seven of this study's "priority lists" (IOC tables F-4 through F-
10, Appendix F) were then compared with the above four EPA priority lists
to determine commonality of the IOC entrants. There are 46 IOC (29 percent
of 161 candidates on the seven "priority lists") common to the four EPA
priority lists. These compounds and certain subsets of- them discussed
in the report are the compounds on the EPA lists that presumably pose
toxic harards on the basis of the readily available toxicity data. Thus
they constitute one group of the IOC that should be considered for future
EPA studies. However there are many (over 100) compounds on the "priority
lists" developed on this study (including both IOC and ODP intermediates
and dyes and pigments) which are not on the EPA priority lists but which
are equally good" candidates for continued EPA investigation. These are
discussed in detail in Sections 7 and 8 in the report.
Problems inherent in the available data must be kept in mind when
attempting to use the master tables or the extraction ("priority") tables
for prioritization of compounds according to toxic hazard potential or
for selecting compounds for continued in-depth EPA studies. These relate
to data availability, data quality and prioritization criteria concerning
the follox^ing:
List of compounds of industrial significance
Toxicity data types and relative availability
Production volume data
Waste stream data
The original list of about 350 IOC upon which this study was based
has been expanded to over 500 compounds (including isomeric forms) in
the course of the study. However there may still be compounds of industrial
significance not included, since it is difficult to determine with certainty
which of the thousands of known organic compounds are actually produced
commercially, when many of them are produced by only one company, frequently
for captive use, and production data are not released. The toxicity data
summary which follows pertains only to the 418 IOC included in Table A-l.
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About 85 percent of the IOC have some toxicity data available, and
75 percent have quantitative data. Only 6.9 percent of the ODP intermediates
and dyes and pigments have quantitative data. It must be emphasized that
toxicity data vary widely in terms of the test protocols folloxjed. The
consequence is that the data types and the reliabiliity of the data produced
also cover a considerable range. Thus specific toxicity data types that
can reasonably be compared for toxic hazard purposes are much fewer in
number than the overall amount of available quantitative data indicate.
The most prevalent common protocol data are oral data obtained on rats
to determine the amount of a chemical producing death within several days
to a week (acute toxicity) in 50 percent of a rat population (LD50, oral-
rat) . These data are available on 50 percent of the IOC. Other specific
data types are available on 29 percent to 5 percent, or less, of the IOC.
All these data were of necessity extracted from secondary literature sources
(toxicity data compendia) which do not provide information on the quality
of the specific data. Analyses of replicated data, where it is available,
have shown that the agreement ranges from excellent to poor (data value
ratios of essentailly 1 to 50 are observed) . These data availability
and data quality analyses show that the "priority" or "rating" schemes
described above, which are based on simple arrays according to selected
quantitative toxicity data types, must be used with caution. Also they
indicate the need for additional, common protocol, toxicity testing on
many compounds that already have quantitative toxicity data.
Production volume data were obtained on about 40 percent of the Table
A-l IOC, as follows:
Production Level, Number of
_ Ibs/yr _ Compounds Listed
9 36
10 -10y 66
. 107-108 52
106-107 9
Thus there are at least 102 IOC with production levels of 100 million
Ibs/yr and 193 total compounds with quantitative .production data. Most
of the high volume products (^10° Ibs) have some types of quantitative
toxicity data available but the types vary greatly, as described above.
However there are also 60 percent of the IOC (80 percent of ODP inter-
mediates and dyes and pigments) which have no production volume data readily
available. It would be desirable to establish whether any of these compounds
are high production level items.
The amount of the IOC or ODP escaping to the environment during produc-
tion and use is one of the most important data types bearing on determination
of toxic hazard. There are quantitative data, ranging widely in availability
of specific compound information, on 26 percent of the IOC processes (none .
of the ODP) . This includes effluent data on 4 percent of the IOC and
emissions data on 22 percent of the IOC. The range of effluent and emissions
levels reflecting production factor variations is not available. Neither
is specific information on data collected or analyses protocols. Consequently
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the reliability of the data cannot be assessed at present. Furthermore
there is an obvious need for obtaining more quantitiative data, especially
on more toxic compounds for which no such data are presently available.
The attempts to establish definitive criteria for prioritizing the
IOC and ODP according to toxic hazard have so far succeeded only in producing
a substantial set of potential criteria. These are listed in the report
together with the steps taken to produce them. In the absence of a formula
that would allow quantitative, or even qualitative, evaluation of all
important criteria factors, simplistic "prioritization" or "rating" schemes,
as described above* were devised based solely on toxicity and production
volume data.
An assessment of the state of the art of pollution control technology
for handling effluents and emissions from the IOC and ODP industries was
carried out. It was determined that most of the published information
on these technologies and the processes to which they are applied is of
a general nature. These facts, plus the extremely large number of compounds/
processes involved in-this study, and the very large percentage of expenditure
of available time and funds required to satisfactorily tabulate and analyze
the toxicity, process, production volume, waste and use data, led to a
decision to limit the control technology assessment to general coverage.
Summaries of the major pollution control equipment and techniques applicable
to the control of the effluents and/or emissions from IOC production process-
es are presented, together with some comments on their strengths and weakness-
es. Since the applicability and efficiencies of organic pollutant removal
varies widely depending on the specific chemical/process, it was not found
possible to specify "best" technologies on a generalized basis. Further
assessment .of control technologies will be required in future studies.
The ODP industry and its special requirements for effluent treatment
are discussed in a separate section of the report. In view of the unique
situation this industry faces in controlling pollutants and because of
the rather small amount of published information this study found, three
companies producing ODP were interviewed to obtain first-hand opinions.
The concensus of these interviews, unsubstantiated by independent corrobora-
tion, is that gas and vapor emissions can be effectively controlled by
the use of commercially available absorbers, scrubbers, and filters, while
effluents (except for highly toxic heavy metals) can be controlled by
a central treatment facility. An advanced, proprietary water treatment
system now being tested in full scale operation at a plant manufacturing
disperse dyes has been described to Battelle as very promising. This
system is described in the report.
One environmental pollution problem peculiar to the ODP industry
results from the production of dyes with a significant solubility in water.
Sodium chloride added to "salt out" or precipitate the dye product results
in effluent containing large amounts of salt and much larger amounts of
colored substances than are encountered from other dye or pigment processes.
Plants using this type of process should be located near the ocean to
avoid contamination of fresh water with salt.
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The outputs of this study described above provide the EPA with a
foundation data base and a preliminary analysis of the toxic hazard potentials
presented by the IOC and OOP industries and their hundreds and thousands
of products. However, in view of the extreme complexity of these industries
and the present state of toxicological data availability and understanding,
the study should be viewed as a beginning effort. More work needs to
be done to insure that all the important data (commercially'produced chemicals,
toxicity data, production volumes, waste products data, end use patterns,
environmental stability) have been obtained. Potentially important sources
of this information which were not utilized on the present study due to
time and funding constraints include the producing companies themselves
(product brochures, annual reports, personal contacts), industry organizations
(published reports, personal contacts) and the primary literature (computer
searches of Chemical Abstracts, Index Medicus, Predicasts, etc and retrieval
of significant articles). Collection of information by these routes would
be time consuming but might provide significant amounts of new and important
data.
Considerable additional evaluation of the presently available data
is also possible. Perhaps the most valuable approach would be to expand
or modify the Radian Corporation computer data base to include the new
data from the present study. This would allow more facile compilation
and comparisons of "priority" lists. Also compilation of the various
data types keyed to specific chemical structural features would become
possible. However, even without a computer aid, further analysis of the
present data base is possible. Additional extraction table compilations
of potential value can be constructed.. These could include:
Compounds listed according to decreasing production
volume correlated with various specific toxicity data
Compounds listed in order of toxicity data not yet
specifically analyzed (e.g., LD50, animal data obtained
by administering the chemical by routes other than
oral or inhalation)
Compounds listed in order of total organics emissions
(quantitative data).
Of course continuation of efforts to identify the important criteria for
evaluating toxic hazard potential are certainly in order. Finally, further
assessment of control equipment and technology needs to be carried out.
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SECTION 2
INTRODUCTION
Industrial organic chemicals (IOC) and organic dyes and pigments
(ODP) are derivative products from naturally occurring materials, largely
petroleum and natural gas, which have undergone at least one chemical
reaction such as oxidation, hydrogenation, halogenation, sulfonation,
nitration or alkylation, and which will undergo at least one additional
chemical reaction before leaving the industry, or be used in a solvent
or coloring function. The production of primary organic raw materials
by the petroleum refining industry via distillation, cracking, and reforming
operations is specifically excluded from this study. IOC and ODP chemicals
are further identified under the 1972 Standard Industrial Classification
Manual (SIC) of the U.S. Department of Commerce. These include group
286, Industrial Organic Chemicals subcategories Industry No. 2865, Cyclic
(Coal Tar) Crudes, and Cyclic Intermediates, Dyes, and Organic Pigments
(Lakes and Toners) and Industry No. 2869, Industrial Organic Chemicals,
Not Elsewhere Classified. However certain classes of compounds covered
by these SIC codes are excluded from consideration. These are pesticides,
herbicides, insecticides, other agricultural chemicals, pharmaceuticals,
explosives, plasticizers, and coal tar residues and distillates other
than cresols or other chemically distinct compounds. There are also some
grey areas of compound classes such as tanning agents, rubber processing
chemicals, and flavoring and perfume chemicals X7hich are not covered system-
atically, although a few chemicals from some of these groups do appear
on the master tables.
The specific chemicals to be covered in detail in this study were
those contained in the Industrial Process Profiles for Environmental Uses.
Volumes 6 and 7. These volumes are entitled, respectively, "Industrial
Organic Chemicals" (1) and "Organic Dyes and Pigments" (2) (references
are listed on page 61). Volume 6 (March 30, 1976, draft) is undergoing
extensive revision. Consequently some of the process description data
extracted from Volume 6 and presented in this study will need to be similarly
revised. This is discussed in the text.
The production of organic chemicals, as defined above, has grown
tremendously in both volume and importance, in the several decades since
the Second World War. The organic chemicals industry provides the raw
materials used by at least ten other major industries. These are (1)
plastics and resins, (2) synthetic fibers, (3) synthetic rubber, (4) solvents,
(5) plasticizers, (6) pharmaceuticals, (7) dyes and colorants, (8) surfact-
ants, (9) explosives, and (10) agricultural chemicals, including herbicides
and pesticides. As the number and total amount of organic chemicals commer-
7
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cially produced has expanded, the type and quantities of these chemicals
escaping to the environment during manufacture and use has exploded according-
ly. Emissions of volatile compounds represent by far a greater variety
of chemical types than are introduced from all other stationary sources
combined. Yet, collection of information on which compounds are emitted
in what quantity, and what sort of toxic hazard they pose, is only beginning.
Quantitative data are relatively sparse and of uncertain accuracy. Commerical
introduction of organic chemicals into surface and groundwaters also poses
great problems, but quantitative data on specific chemicals are again
sparse. It has become increasingly clear in the past decade that many
of these chemicals, either because of inherent toxic properties, or because
of the sheer volume of their release or, in some cases, their persistance
in the environment, are hazardous. ....
In fact, toxic hazard crises related to this industry are occurring
with dismaying frequency. Thus a number of individual compounds (e.g.,
B-naphthylamine, DDT, dioxin, vinyl chloride, kepone, etc) have been first
exposed as potent health or environmental hazards and then subjected to
very close scrutiny, but organic chemicals as a class have only just begun
to be investigated. In the face of these facts and with a comprehensive
federal toxic substances act just enacted, the EPA has recognized there
now exists an urgent need for well organized and correlated baseline data
and information on the range of compounds produced. This includes the
following information on these compounds:
identification of as complete a list of commercially
produced compounds as possible
o comprehensive toxicity data
producing companies and plant sites
production process details
production volumes
environmental loss modes and amounts
technology to control or eliminate escape or loss
downstream product uses (normal product fate).
Consequently the present study was contracted by the EPA as one initial
effort to meet these needs. The specific purpose of this project was
to prepare a report containing comprehensive, collated information on
portions of these need areas listed below. This report could serve as
a convenient, single source of .quickly available, detailed information
on specific compounds or as a guide to identifying and selecting groups
of compounds for evaluation, field study, effluent or emissions standards
studies, etc. To obtain the information needed to compile the report,
this study addressed the following subject areas:
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(1) Identify potentially hazardous materials
(2) Compare the chemical products selected with various EPA
priority lists
(3) Assess the treatment and control technology of emissions
from production processes
(4) Identification of the major uses of the most hazardous
materials
(5) Provide summaries of the effectiveness of treatment and
control technologies and suggest areas in which new or
improved technology is needed.
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SECTION 3
OBJECTIVES
The overall objectives of this task study were the following:
(1) Identify the potential hazards associated with the
production and utilization of industrial organic
chemicals and organic dyes and pigments.
(2) Determine the state of the art of technology for the
treatment and control of the potentially hazardous
wastes generated during the manufacture and use of
these materials.
The general approach taken to assess the potential hazards of
the IOC and ODP industries was to conduct a computerized and hand literature
search and quickly assess the output to select appropriate documents
for use in the study. Because of * the very short time period (10 weeks)
originally allotted for the entire study, only readily available secondary
literature (books, encyclopedias, monographs, readily available government
reports) were sought. Primary literature such as papers containing
original data were not sought. Then an intense data selection and
organization effort was mounted to provide collated information for
evaluation as quickly as possible. To reach the objectives the fol-
lowing specific subtasks were established and carried out concurrently:
Subtask 1; Identify the sources of both industrial organic
chemicals and organic dyes and pigments included
in the Industrial Process Profiles and the wastes
associated with their production.
Subtask 2; Obtain and codify published data on the toxicity
or hazardous nature of industrial organic chemicals
and organic dyes and pigments.
Subtask 3; Propose criteria for ascertaining the relative
importance of the hazardous nature of the dif-
ferent potentially toxic and hazardous chemicals.
Subtask 4; Assess the state of the art of treatment and
control technology for both production processes
(Subtask 1) and for major uses of potentially
the most toxic and hazardous chemicals (Subtask 3).
10
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Subtask 5: Identify areas where additional data or infor-
mation is needed to satisfactorily complete
Subtasks 1 through 4.
Subtask 6: Make recommendations for research and development
on new or improved control equipment or technology.
11
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SECTION 4
IOC AND ODP INDUSTRY COMPARISONS
The two major groupings of IOC and ODP were studied and organized
into separate collated data sets. This was dictated primarily by the
fact that the basic information on each was available in separate documents
arranged according to different and basically incompatible formats.
This in turn reflects the facts that ODP production is a major and
completely segregated subgroup of the organic chemicals industry dependent
on highly specialized batch processes while IOC production is, for
the most part, characterized by much higher volume continuous processes,
many of which are vapor phase and/or do not require intimate process
water contact. Most IOC products are low molecular x
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SECTION 5
RESEARCH APPROACH
To meet the objectives of the study, the following methodology was
adopted:
(1) A literature search was conducted [hand and computer - //'
Systems Development Corporation (SDC) Off-Line Citation
List producted from National Technical Information Center
(NTIC) files].
(2) Master tables of industrial organic chemicals and
organic dyes and pigments containing correlated
toxicity, process, waste, production volume, and
use data were assembled. These central data
repositories were then used in all subsequent work.
(3) An attempt was made to identify and propose criteria
for ascertaining the relative importance of the hazard
posed by the chemicals.
(4) Various lists of data were extracted from the master
tables. Some of these lists can be viewed as "priority
lists".
(5) Various EPA toxic chemicals priority lists were acquired
or assembled and compared with the extraction lists.
(6) An assessment of treatment and control technology was
undertaken.
The literature search emphasized the identification of appropriate
major secondary data compilations which could be used to prepare the master
tables. A computer search produced _259 government reports while about
20 standard reference works_pertinent to Subtasks 2, 3, and 4 were identified
ahcFobtained tfirough the Battelle library facilities. The most important
and frequently used references are Items (1) through (16), on pages 61
and 62. These references include process and compound sources (1,2,10,12),
toxicity compilations (3,4,5,9,15), production volume data sources (7,10,11,
12,14), and information on uses (5,8,13,16).
The compilation and processing of the master tables, which are presented
in Appendices A and B, turned out to be a massive undertaking which required
a major portion of the effort. However, the output of this effort represents
13
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what is believed to be a. valuable and unique set of information never
before assembled in such a fashion. These tables are discussed in detail
in the next section. They are central repositories of correlated data
that serve as the main output and focal point of the study.
The effort to identify and establish criteria for priority rating
industrial organic chemicals and organic dyes and pigments proved to be
a very difficult and challenging task. Suggested criteria and approaches
for using them are listed and discussed but no formal approach adopted
as yet. This work is discussed in Section 8, starting on page 38.
In the absence of solid, detailed criteria for identifying hazardous
materials at the present time lists of chemicals based on various types
of toxicity data or production volumes were extracted from the master
tables. Mostly these are based on raw toxicity data arranged in numerical
sequences of decreasing toxicity. Some of these extraction lists are
correlated with quantitative waste data and production volumes. These
lists can be handled as "priority" lists for the present, although their
use must be undertaken with considerable care, keeping in mind the simplis-
tic approach with which they were assembled.
Nonetheless, these "priority" lists of IOC and ODP can be compared
with various EPA priority lists that were obtained or assembled. In this
way different lists or methods of ranking IOC and ODP for potential hazard
can be compared to determine degree of commonalility and to aid in selecting
highest priority compounds/processes for further study.
Literature pertaining to treatment and control technology was also
obtained. Evaluation and compilation of this information has allowed
summaries of the state of the art in effluent and emissions control to
be assembled. The applicability of these controls to specific processes
is, however, beyond the scope of this present project. Also three industry
contacts were made concerning orgnic dyes and pigments, since relatively
little published information is available on pollution control in this
special segment of the chemical industry. Some very interesting information,
presented in the discussion of ODP (page 51), was obtained during these
contacts.
In summary, an initial assessment of the information and data pertinent
to the potential hazards posed by the production of IOC and ODP by industry
can be accomplished by the results described in the following sections.
However, in view of the breadth and complexity of this industry and the
present state of toxicological data availability and understanding the
study must be viewed as a_ beginning effort which has not yet probed the
subject in depth with the funds and time allotted.
14
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SECTION 6
MASTER TABLE COMPILATION
Master tables of toxicity, process, waste products, production volume,.
and end use data (Appendices A and B) were assembled. The main lists
of organic compounds and organic dyes and pigments 'that are included ,
were taken from the Industrial Process Profiles for Environmental Use, /-
Volume 6, "Industrial Organic Chemicals" (Appendix D, reference 1) and
Volume 7, "Organic Dyes and Pigments", (Appendix D, reference 15). These
draft EPA compilations of industrial chemical process information, which
are presently being edited by Radian Corporation, Austin, Texas, were
chosen as the basis for this study since they were the most recent comprehen-
sive compilations of process and end use data available when this quick
response task was started. The comprehensive toxicity data presented
were taken from the major available compendiums (Appendix D, references
2, 3, 4, and 8). These master tables now comprise the basic tools for
addressing the major task of assessing the toxic hazard posed by the
production and use of industrial organic chemicals (IOC) and organic
dyes and pigments (ODP). Once the degree of toxic hazard posed by the
products and their associated waste streams (emissions, effluents, sludges,
and solids) has been established, an assessment of applicable waste and
pollution control technology will be possible.
INFORMATION INCLUDED IN MASTER TABLES
The tables are arranged as facing page (two page) layouts x^hich
present, on the left hand page the folloxdLng information:
Name and formula (where applicable) of IOC or ODP
Chemical Abstract Registry number and Wiswesser Line
Notation (WLN) identifying symbols
o Oral toxicity data - LD50 refers to the dose that produces
death in 50 percent of the exposed animal population.
Any value - 500 can be considered a potential toxic
hazard. Also LDLo (Lowest lethal dose) data are listed here.
Toxic hazard rating
3 = very toxic, small to moderate exposure can
produce death or permanent injury
15
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2 = moderately toxic, serious effects can be produced
but they are usually reversible
1 = very low toxicity, effects usually slight and
readily reversible
0 = essentially nontoxic
U = not listed
Toxicology - includes all toxicity data other than
oral LD50 and LDLo, and carcinogenic data. Thus
all other administration routes (skin, inhalation,
etc) are presented here. Definitions of exposure
mode acronyms are in Appendix C. Also listed there
are summary narrative descriptions of human or
animal physiological symptoms or malfunctions.
Threshhold limit value (TLV) - includes current .
and recommended U.S. occupational standards
Carcinogenic data
On the right hand page of the tables are presented the following:
Sources of products (raw materials, catalysts,
solvents)
Process number from Appendix D references 1 or 15
Process type (ammonolysis, oxidation, etc)
Waste stream information (quantitative data when
available - emissions factor units are Ibs/ton)
Waste treatment used in present process (when available)
Total production of IOC in millions of kilograms
(pounds)-year; OOP in thousands of kg (Ibs)-year
Uses of compound, especially downstream syntheses
or manufacture of new organic chemicals, polymers,
etc (quantitative use patterns presented where
available)
References (Appendix D)
The information contained in the master tables, as outlined above, is de-
scribed in greater detail in the following sections.
16
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Name and Formula
The name under xjhich the compound is listed in Appendix D references
1 and 15 is listed first for both IOC and OOP. IOC are then further
identified in most cases with an alternative descriptive name and molecular
and empirical formulas.
Identifying Symbols
The Chemical Abstract (CA) registry number and Wiswesser Line Notation
(WLN) are listed for most of the compounds. The CA number is a unique
identifier in the American Chemical Societies' Chemical Abstracts index
system. It provides a search key if future literature searches for
information on specific compounds are needed.
WLN symbols were taken from reference 2 or determined, as needed.
They express chemical compound structures as a linear string of symbols.
The resulting notation is compact and unique for each compound. It
is particularly suitable for computer processing, especially for sorting
compounds on the basis of selected functional group or structural features
such as amino, chloro, benzene rings, etc, or combinations of features.
Thus computer storage of compound and process data, keyed to WLN symbols,
will allow facile recall and display of toxicity data (and other data)
for compounds or sets of compounds. Eventually computer storage should
provide a tool for helping to develop criteria for rating toxic hazard.
Once such rating criteria are established computer processing can be
expected to aid in prioritizing compounds/processes for various purposes
relative to.potential hazard.
Toxicity Data
Toxicity information presented, as outlined above, includes various
acute and chronic quantitative test data, together with qualitative
hazard ratings and narrative summaries of physiological symptoms and
malfunctions. Almost all of the quantitative data were obtained by
administering the test compound to a group of animals using a particular
exposure route, although a few quantitative human data, based on accidental
exposures are also listed.
Acute Toxicity Data
The most readily and frequently obtained toxicity .data are acute
data obtained by single dose administration followed by observation
of the animals for several hours to 1 week. Symptoms and death or death
rate are commonly the data recorded. Proper determination of LD50 data
is accomplished by delivering different quantities of the test compound
to various groups of animals and statistically determining the dose
producing 50 percent deaths. Lethality estimates other than 50 percent,
e.g., 1 percent, LD1 or 99 percent, LD99 can also be determined. Lowest
lethal doses (LDLo) are also obtained using these test procedures.
Inhalation tests to determine LC50 values are similar except the experiment
must involve a finite exposure time (preferably 4 hours) in addition
to controlled air concentrations of the test compound. Results of acute
17
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tests on different species can show the spread of biological variation
and reveal, for example, the major organs or systems involved, assuming
of course that the data have been obtained under conditions that allow
valid comparisons. A problem inherent in the toxicity data compilation
in the master tables is that the data are extracted from secondary compila-
tions. Consequently direct assessment of the precision or accuracy
of the data is not possible.
Acute toxicity test data, especially LD50 values obtained by the
same administration route (equivalent test protocols), can normally
be considered comparable for at least first approximation rating purposes.
This is done and extraction (rating) tables are discussed in Sections
7 and 8. Even LD50 data obtained using different animals but the same
administration route are generally usable for at least order of magnitude
comparisons. This can be seen, for example, by scanning the LD50, oral
test data in Tables A-l, A-l Addendum, B-l and B-2. There are exceptions,
of course, and some of these are summarized later, on pp 30 and 31.
A useful toxicity comparison scale for this study (cf references
3, page xviii and 17, page 19) is the following:
Acute LD50 Value Scale
^1 mg/kg poisons
1 to 50 mg/kg highly toxic
50 to 100 mg/kg very toxic
100 to 500 mg/kg moderately toxic
0.5 to 5 gm/kg slightly toxic
>5 gm/kg essentially nbntoxic.
A similar LC50 scale (inhalation data) can be constructed by letting
2 ppm (% 0.4 mg/nH) inhalation exposure be considered equivalent to
1 mg/kg on the LD50 scale. On this basis, an oral LD50 of 500 mg/kg
would be considered equivalent to an LC50 of 1000 ppm (or * 200 mg/m^)
inhalation exposure (preferably 4 hour exposure). This arbitrary rating
scale will be used as the basis of identifying categories of toxicity
in subsequent discussions in this report.
Chronic Toxicity Data
Quantitative chronic test data presented in the tables include
carcinogenic, teratogenic and mutagenic data. These data types are
obtained by studying the effect of repeated administration of the compound
over varying periods of time, usually months or 1 or more years. Of
necessity this type of test covers an appreciable span of the typical
animals lifetime and requires careful test design, including control
groups. All animals must be subjected to pathological examination.
Data recorded under carcinogen include both true carcinogens', i.e.,
cellular tumors which are normally fatal or are associated with the
formation of secondary tumors (metastasis), and neoplasms, i.e., all
other tumors. These data represent an extreme range of test conditions,
i.e., animal type/dose administration route/exposure mode and time.
Thus ranking carcinogenic data for comparison purposes is very difficult,
18
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even though it is clear that some compounds are appreciably more potent
carcinogens than others. An unordered list of compounds producing carcino-
gens or neoplasms (as determined by testing on animals) will be presented
later. Teratogenic (nonhereditary birth defects) and mutagenic (permanent
genetic changes) effects data are the other quantitative chronic data
listed. Chronic affects such as irreversible renal, hepatic, heart, central
nervous system, etc, damage produced by long term exposure are covered
by the narrative summary discussions under the toxicology heading. Shorthand
summaries of both acute and chronic effects are presented under the toxic
hazard ratings. Reference 3 (Sections 9 and 12) should be referred to
for & fuller explanation of this information and more complete data where
desired.
Additional Background on the Toxicity Data
It is necessary to refer to the abbreviations and acronyms list (Appen-
dix C) in order to decipher the toxicity entries in the tables. A more
thorough discussion of the subtleties and intricacies of toxicological
testing and the nature of toxicity data are beyond the scope of this study.
However these factors should ultimately be considered in determining toxic
hazard priorities. For a more complete description of this subject the
reader is referred to Appendix D (2,3), especially to the criteria section
in (2) and sections 9 and 12 in (3), and to reference 15 (References p
61), chapters 2-5, 10, and 13 in particular.
TLV
Threshold limit values were established originally by the American
Conference of Government Industrial Hygienists. They were adopted by
OSHA in 1971 as official occupational workplace standards (U.S.O.S. or
United States Occupational Standards). TLV's were established on the
basis of the best available information from industrial experience and
from experimental human and animal studies. They are not intended as
a relative index of hazard or toxicity. However these standards do indicate
the level of concern they engender as individual compounds on the basis
of workplace experience and experimental toxicity data.
Compound, Process, and Waste Data
These entries are summarized adequately in the outline. Information
in these columns found in Tables A-l and A-2 and B-l through B-4 was taken
from Appendix D, refences 1 and 15. .Additional data on wastes (emissions
factors) was derived from reference 12. Since reference 1 is undergoing
extensive editing and revision by Radian Corporation it will be necessary
to change some of the entries under these headings in the near future.
This is particularly true of the process numbers. Quantitative waste
stream data taken from reference 1 (Air: and Water: data) are presented
in the original units. The emissions factors units are Ibs of emitted
chemical per ton of product.
Total Production Volumes
Production data are for total product, summed for all processes,
taken from Appendix D references 6, 9, 10, 11, 12, and 14. They are
' 19 ,
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kg (106 lbs)/year (IOC) and 103 kg (103 lbs)/year (ODP).
Uses
Qualitative use data are adapted from Appendix D, reference 1 while
quantitative use patterns are from reference 13. The quantitative use
data in Appendix D, reference 13 were compiled from Appendix D reference
6 and reference 16, page 62.
DATA AVAILABILITY
Industrial Organic Chemicals
As described earlier, the basic list of IOC.used in compiling Table
A-l was taken from reference 1. Table A-l contains an extensive listing
of the IOC (418 numbered items). These include 353 different basic organic
chemicals, plus 65 isomeric forms. Hox^ever as the compilation of Table
A-l proceeded it became apparent that not all organic chemicals that should
be included in this study were in reference 1. Since this determination
was made about 170 additional compounds have been identified from various
sources (Tables E-l through E-6, Appendix E; and Tables G-l and G-2, Appendix
G) that are considered potential candidates for inclusion as IOC. These
tabulated sources of the 170 additional compounds include the following:
(1) Table E-l. Radian List of Compounds to be Added to the
List of Industrial Organic Chemicals
(2) Table E-2. Industrial Organic Chemicals Not on the IOC
List or on Table E-l - from a 1975 Petro-
chemical Compilation^a'
(a) Hydrocarbon Processing
(3) Table E-3. 1973 U.S. Tariff Commission Report Compounds
Not Elsewhere Listed
(A) Table E-A. Additional Compounds to be Considered for
Inclusion in IOC Table A-l(a>
(a) Randomly identified.
(5) Table E-5. Compounds Not Already Included Which Are
Covered by Effluent Limitations Guidelines
Development Documents - Organic Chemicals
Industry
(6) Table E-6. Organic Chemicals in IPPEU-IOC but with no
Process Number - Possible Additions to the
IOC List
(7) Table G-l. Water Quality Planning and Standards
Consent Decree List
(8) Table G-2. Potentially Significant Air Toxicants from
20
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the Office of Air Quality Planning and
Standards (AQPS).
A group of 93 of the approximately 170 candidates was identified as being
pertinent due to knoxm or probable commercial availability, presence on
an EPA priority list, or the availability of toxicity data that represent
a potential hazard. Consequently these compounds were tabulated using
the same format as Table A-l in Table A-3. Industrial Organic Chemicals
Addendum - Toxicity, Process, Waste, Production and Use Data. Nineteen
(19) of these compounds were among 33 listings suggested for addition
to reference 1 by Radian Corporation (Table E-l above) in their compilation
of the Organic Chemical Producers Data Base Program (Appendix D, reference
12). These compounds are identified with the Radian identifying (computer)
number in parentheses, under the Table-A-3 item number. The. remaining
14 compounds listed by Radian were already included, either in Table's
B-l or B-2 (ODP raw materials or intermediates), or had already been incor-
porated in Table A-l earlier.
Inorganic chemicals associated with the production of the IOC of
Table A-l are listed in Table A-2 for information purposes. Many of these
compounds are quite toxic and may sometimes be found in waste streams
from IOC production. The consideration of these inorganic chemicals is
outside the scope of this study but they may need consideration in follow-
on studies.
Organic Dyes and Pigments
The ODP master tables include raw materials (Table B-l), intermediates
(Table B-2), and dyes and pigments (Table B-3) taken from Appendix D,
reference 15. There are 32 raw materials used in ODP production listed
in Table B-l. Three of these compounds (item numbers 11, 26, and 31)
are inadvertent repeats from Table A-l. In addition, 86 compounds listed
in Table A-l are maked DP, indicating that these are also dye and pigment
raw materials. Thus, there are a total of 115 ODP raw materials included
in these two tables. ODP intermediates (764 items) are listed in Table
B-2. However, 42 of the numerical sequence of listed items are actually
cross-reference indicators, so that the number of unique compounds listed
is 722. In addition, 26 of these are also in Table A-l, so that the number
of new compounds is actually 696. ODP are found in Table B-3 (1458 items)
and Table B-3 Addendum (30 items). However, ODP in the addendum table
are only modifications (e.g., food dye forms) of the OD? in Table B-3.
Essentially the same data was obtained on these items as for IOC.
The major differences were that appreciably less toxicity and production
data (Appendix D, references 9 and 10) were found but that many more compounds
had to be searched to obtain these data. Some qualitative but no quantitative
waste data were available. No attempt was made to identify end uses for
specific ODP. Inorganic chemicals associated with ODP production are
listed in Table B-4, along with inorganics in Table A-2 marked DP. The
same comments apply to these inorganic chemicals as were made earlier
for IOC-associated inorganics.
21
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Toxicity Data - IOC
A brief summary of the various tabulated toxicity data is provided here
to show the extent of available data. These data are tabulated in various
extraction tables discussed below and also in Section 6 - Data Extraction
Tables Ccf Appendix F}. The data are extracted from Appendix A, Table A-l.
Quantitative Human Toxicity Data
Human toxicity data are available on 59 compounds (14 percent of IOC).
These data are listed in Table F-3. Examination of this table shows 22 re-
ported lethalities resulting from exposure to specific compounds.
Carcinogenic, Teratogenic and Mutagenic Data
Carcinogenic or neoplastic effects have been observed on 71 (17
percent) of the IOC (Table F-4). Of these, about 15 are either known
human carcinogens or show potent carcinogenic activity in animal tests.
Also 7 compounds (Table F-5) have teratogenic or mutagenic data.
Quantitative Oral Toxicity
The master table of IOC (Table A-l) contains 418 number compound
listings. These include 353 different basic organic chemicals, plus
65 isomeric forms. There are 279 (67 percent) of these compounds with
quantitative oral toxicity data of widely varying types. However, the
most prevalent toxicity data that can be fairly compared for evaluating
relative toxic hazard is LD50, oral-rat. These data are available on
208 (50 percent) of the 418 compounds (Table F-6). Of these data, 57
values (27 percent of 208, 13.5 percent of 418) are -.500 mg/kg. These
compounds are given ordinal ratings as a function of decreasing toxicity
in Table F-6.
Also 120 compounds (29 percent of 418) have LD50, oral-animal other
than rat. Of these data, 91 are on compounds that also have LD50, oral-
rat data, i.e., they are overlap data. However 29 (7 percent of 418)
of these data are on compounds that do not have LD50, oral-rat data,
with 4 of these (1 percent of 418) values ^ 500.mg/kg (cf Table F-7,
rating no's 1, 3, 6, and 7). Also listed in Table F-7 are an additional
13 compounds with LD50, oral-animal other than rat toxicity data - 500
mg/kg. These are compounds which have LD50, oral-rat data > 500 mg/kg.
Thus a total of 237 (57 percent) of the 418 IOC compounds have some
type of LD50, oral data, with 73 (17.5 percent) showing some values
£ 500 mg/kg.
There are also 95 compounds with LDLo, oral-any animal data. Twenty
(20, 4.8 percent of 418) of these compounds (Table F-8) have LDLo, oral
- 500 mg/kg, but do not have LD50, oral-rat data at this toxicity level.
Summarizing to this point, oral toxicity data values - 500 mg/kg
are available as folows:
LD50, oral-rat 57 compounds
LD50, oral-animal other than rat 17 compounds
LDLo, oral-animal other than rat 20 compounds.
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Thus, about 94 (23 percent) of the IOC have acute oral toxicity data
that indicates they may represent toxic hazards.
Quantitative Inhalation Toxicity
There are quantitative inhalation toxicity data on 113 (27 percent)
of the 418 IOC. Twenty-eight (28, 7 percent) of these are LC50 data,
while the rest are LCLo or TCLo data. The LC50 data (Table F-9) include
about 16 compounds (3.S percent of 418) showing lethality at about the
1000 ppm or lower exposure level (variable animal and exposure time).
About 9 (2 percent) of these compounds show lethality at the 500 ppm
or lower level. The rating order shown must be considered approximate
in view of the variations in the tests and results (animals, exposure
time, units).
Additional Quantitative Toxicity Values
A number of remaining toxicity data, varying widely in terms of
animal, chemical administration path and exposure mode/time are grouped
together in Table F-10. Only those data ^ 500 mg/kg or 1000 ppm are
included and the data are arranged alphabetically according to compound.
There are 59 items (14 percent of 418), listed in unordered fashion
due to the wide variation in the data types.
IOC (Table A-l) Summary
About 85 percent of the 418 IOC have some toxicity data (quantitative)
or information (qualitative, e.g., toxic hazard rating) presented.
About 75 percent have quantitative data while the remaining 10 percent
have only qualitative information. However, it must be emphasized that,
in spite of the rather numerous quantitative data presented, by far
the most prevalent data obtained under conditions that permit reasonably
valid data comparisons are LD50, oral-rat. These data are available
on only half the IOC. Also most of the compounds that do not have LD50,
oral-rat data have no common data base, since the other LD50 data, the
LC50 data, and the LDLo and LCLo data are each available on only about
29 percent, or less, of the IOC and were obtained using a wide range
of animals and exposure modes. Thus there is only moderate internal
consistency in these data. Overall the available data may be summarized
as follows:
Percent of
Compound category or toxicity type IOC
Toxicity information of any type 85
Quantitative toxicity dataall types . 75
Oral toxicity dataall types 67
LD50, oralall animals 57
LD50, oral-rat 50
LD50, oral-animals other than rat 29
Inhalation toxicity dataall types 27
LDLo, oralall animals 23
Carcinogenic or neoplasem dataall types 17
LC50, ihlall animals 7
LC50, ihl-rat 5
23
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There are sufficient toxicity data available to provide a basis for determin-
ing the relative hazard potential of most of the high volume IOC. Consequent-'
ly, the task.of selecting candidate products/processes for such purposes
as new source performance standards evaluations can go forxjard. However
there are serious gaps in the toxicity data base, as demonstrated above,
and searches for additional data and identification of compounds requiring
additional experimental toxicity evaluation should be instituted.
Toxicity Data - IOC Addendum
There are 93 additional IOC compounds recommended for addition to
the master IOC list in Table A-3, together with the readily available
toxicity data. These IOC compounds show a similar breakdown of available
toxicity data. Inspection of this table (there are no_ extraction tables)
shows LD50, oral-rat available on 38 compounds (41 percent). Sixteen
more compounds (17 percent) have other LD50 data or LC50 data. Of these
data 14 LD50, oral-rat values (15 percent) are ^ 500 mg/kg and 6 (6.5
percent) other LD50 and LC50 values ^ 500 mg/kg or ^ 1000 pptti are available.
Thus 58 compounds in this table (62 percent) have LD50 or LC50 toxicity
data with at least 20 of these data (21.5 percent) indicative of potential
hazards. Twelve compounds (13 percent) have carcinogenic data, with about
4 of these showing potent carcinogenic potential. Thus the data are similar
in availability to master Table A-l, with slightly less data available.
IOC Toxicity Data - Overall Summary
To summarize, the combined IOC data compilations show that a good
amount of toxicity data is available. About 85 percent of all IOC covered.
have some type of toxicity data. These data should prove very useful
in rating the potential hazard of IOC when analyzed together with other
factors such as production volumes, losses to the environment during produc-
tion (waste stream factors), significant use patterns, and other factors
such as physical and chemical properties and environmental stability.
Some serious gaps are identified in the toxicity data base. For
example, the data presented identify a number of compounds that are candidates
for LD50, oral-rat testing, in order to provide a more complete common
data base. Also volatile compounds that do not presently have LC50 data
and numerous compounds that do not have carcinogenic test data but might
be anticipated to show carcinogenic potential are present. These data
gaps can be filled in one of two ways. Searches of the primary literature
can be done to obtain data not yet added to the secondary compendiums
used as data sources in the present study. The data gaps still remaining
should then be filled by additional toxicological testing. Compounds
to be tested and toxicity data to be sought should be selected only after
careful analysis of the updated data base.
Toxicity Data - ODP (Appendix H)
ODP Raw Materials and Intermediates
There are LD50, oral-rat data on 10 of 31 (32 percent) ODP raw materials
(Table H-4), with 5 of the values (16 percent) ^ 500 mg/kg. Only 48 (6.5
24
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percent) of the 722 intermediates have LD50 oral-rat data with 15 (2 percent)
£ 500 mg/kg (Table H-5). There are 7 dyes (Table H-5) with LD50 oral-
rat data, none of which is below 500 mg/kg. The total list of raw materials
and intermediates (753 compounds) has 13 human toxicity exposure data
(2 lethal) (Table H-2) and 45 carcinogenic data entries (Table H-3).
There are 6 recognized human carcinogens in the intermediates table, and
several more compounds with potent carcinogenic animal test data that
suggest that these compounds should be scrutinized more closely. There
are no inhalation data presented on these compounds.
ODP - Dyes and Pigments
There are 22 (1.5 percent of 1458) dyes and pigments with carcinogenic
data (Table H-3). About 6 of these appear to be potent carcinogens in
animal tests. Only 7 dyes and pigments have oral toxicity data. One
dye has human lethality data (Table H-2) available. No inhalation toxicity
data were found.
ODP Toxicity Data Summary
Toxicity data are available on 150 ODP intermediates and dyes and
pigments, with most of the data on intermediates. This is only 6.9 percent
of the total of 2180 intermediates and dyes and pigments. Hence far fewer
toxicity data are available on this class of products, than on the IOC.
Process Data
References 1 and 15 (Appendix D) were relied on for production process
data, since these prior EPA studies had attempted to obtain this information
in detail. The Radian Organic Chemical Producers Data Base Program (Reference
12) is attempting to update this information on IOC. As additional process
information becomes available, it should be incorporated into an updated
version of the present report.
Waste Stream Data '
Quantitative waste stream data, which includes data on 1 or more
specific compounds in each case, are available on 108 of the IOC (20 percent
of 418). This includes water effluent data on 17 compounds and air emissions
data on 16 compounds from Reference 1 (Appendix D) and emissions factor
data on 94 compounds from Reference 12. These data vary widely in availability
of specific compound information. The range of effluent and emissions
levels relative to industrial production over appreciable time periods
is not available. Neither is information on how the data were collected
or how the calculations were made. Consequently the validity and accuracy
of the data are not known. Only a small amount of qualitative information
is available on ODP products.
Production Volumes
Production volume data were obtained from the best available sources.
Data are available on 163 (39 percent) of the IOC compounds in Table A-
1. They are also presented on 27 (29 percent) of the 93 compounds in
IOC addendum Table A-3. Production data presented cover years ranging
25
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from 1968 through 1975, xjith most data for 1973 (124 items, 30 percent).
1973 is considered the best recent base year for comparing compounds on
the basis of relative production levels, since it represents data prior
to the major perturbations resulting from the oil embargo and subsequent
raw materials and energy shortages, and the effects of the 1974 economic
recession.
ODP production volumes are available on 23 (3 percent) of 722 intermed-
iates (Table B-2) and 273 (19 percent) of 1458 dyes and pigments (Table
B-3).
The major source of production volume data is the U.S. Tariff Commission
(9,10). This government agency collects statistical data on industrial
production directly from the companies. However, quantitative data are
only published if there are 3 or more producing companies. This is done
to protect the confidentiality of the data when only 1 or 2 producers
are involved. Hence, these data are in the USTC files but are unavailable
for public disclosure. All other published data ultimately are derived
from figures released for publication by the producing companies or from
.data estimates based on known industrial capacities and' general production
levels.
26
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SECTION 7
DATA EXTRACTION TABLES
The master tables (Tables A-l, A-2, A-3, B-l, B-2, B-3, and B-4)
are massive compilations of correlated data and information. They can
be used as convenient references for many types of data on IOC or ODP
compounds or processes. However, the information contained in these master
compilations can be put to use much more effectively or efficiently if
various types of data or information are extracted and presented in more
compact correlations. A number of these more readily usable data extractions
have been identified and compiled for use on this task study. No doubt
additional combinations or ways of correlating or presenting the data
can, and will be, devised. Most of the extraction tables have already
been referred to and some of the contents discussed in Section 6, since
they were convenient sources of data on the range of data availability.
Thus their contents and meanings have already been discussed to some extent.
There are two sets of extraction tables presented, those on the IOC in
Appendix F and those on the ODP in Appendix H. There are 12 IOC. extraction
tables (Tables F-l through F-12) and 5 ODP extractions tables (Tables
H-l through H-6). These tables, what is in them and the reasons for their
compilation are described below.
IOC EXTRACTION TABLES
The 12 tables are given in sequence, followed by a brief description
of their contents and usefulness.
U.S. Occupational Standard (USOS) for
Concentrations in Air-Industrial Organic Chemicals
Listed Alphabetically According to Compound (Table F-l)
The USOS are workplace standards developed from industrial experience
and experimental animal studies. They are not intended as relative indices
of hazard or toxicity but they do indicate a level of concern engendered
on the basis of human experience. The list of compounds represents commercial
compounds that have come into question in the past and should therefore
include many of the IOC or ODP that are potential health hazards.
USOS Standards Listed According to
Increasing Standard Concentrations (Table F-2)
Experience has presumably resulted in accidental exposures, or testing
has produced data, on which of the USOS compounds pose the greatest health
27
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threat. Thus listing them with the lowest exposure level compounds first
provides one approach to identifying compounds that should be looked at
very closely across their spectrum of properties.
Human Toxicity Data (Table F-3)
Accidental human exposure data of four types are listed: LDLo, LCLo,
TDLo, and TCLo. The exposure mode and toxic effect are noted, with the
quantitative exposure data. Of particular note are the 22 cases of death
noted after exposure to various of the chemicals (LDLo and LCLo). It
seems reasonable to subject those compounds which have caused human death,
especially at low or moderately low exposure concentrations (cf Table
F-3), -to closer scrutiny. Of lesser note but still important are the
IOC v/hich have produced toxic effects but not death. Again, the compounds
producing measurable effects at the lowest doses or concentrations should
be the greatest cause for concern. Since the modes of exposure and the
resultant exposure levels have varied so widely no attempt has been made
to order the compounds in terms of relative hazard potential. This list
of compounds can be compared with the other lists to be described below,
for commonality of entrants.
Carcinogens or Suspected Carcinogens (Table F-4)
Chemicals which produce tumors (cancerous growths or neoplasms) are
of particular concern today to the average person. This is true even
though acute or chronic health conditions of other types may also be likely
to occur to the average citizen.
In view of the this special interest, carcinogens have been listed
separately in the master tables and have been extracted into Table F-
4. The TCLo quantitative data, administration mode/animal, and toxic
effect noted are listed. As in the case of human exposure data, the nodes
of test and resultant data units are so variable that no attempt was made
to present the compounds in order of decreasing toxic effect. It is not
possible on the basis of the present study to determine which compounds
pose the greatest toxic hazard, beyond those compounds already labeled
as known human carcinogens. Each of these compounds should be viewed
as candidates for further study and for comparison with the other lists
for commonality.
Teratogens and Mutagans (Table F-5)
Six (6) compounds with animal test data indicating that they are
teratogens and 1 with data implicating it as a mutagen, are listed in
Table F-5. It is of interest that 3 of the 6 compounds with teratogenic
data, also have been implicated as potent carcinogens. When this is coupled
with carcinogenic potential, these compounds are of high toxic hazard
potential and should be included in any list of compounds to receive further,
close study.
28
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There are also 2 teratogens and 1 mutagen in this table from the
IOC Addendum list (Table A-3), and 3 dyes that have shown potent teratogenic
characteristics in animal tests. Two of these are also animal carcinogens.
.All categories of chemicals (IOC, OOP) covered by this study were
included in this table because of the small total number of compounds
involved. These compounds should also be compared with the other lists
of toxic data to determine commonality.
Oral Toxicity (LD50, Rat) (Table F-6)
As described earlier this is by far the most prevalent toxicity
data that can be fairly compared for ranking purposes. There are data
on half the IOC, with at least one-fourth (13.5 percent of the IOC)
at an LD50 level (- 500 mg/kg) that can be considered a potential hazard
level. These data are arranged in order of increasing LD50. Of course,
lowest LD50 equates with highest toxicity.
Any data on carcinogenicity (Table F-4) and teratogencity or mutagenicity
(Table F-5) are also listed in the table. Production volumes and the
existence of quantitative waste stream data (Table A-l) are also listed.
Thus, this table is one of the most important extraction tables, containing
four types of correlated information that bear on determining whether
compounds pose a potential hazard and "prioritizing" the relative degree
of hazard posed. The existence of commonality, whether it is 2, 3 or
all 4 data types, and the ranking of each data type (LD50, carcinogenic
potential, production volume, quantitative loss patterns), are all of
obvious importance in determining which compounds/processes are most
hazardous. However, a method of weighting (prioritization criteria)
these widely differing factors is not yet available. Determination
of realistic weighting criteria while difficlut, should be pursued.
It can be concluded, however, that the most toxic compounds (for
example, the first 57 items in Table F-6) should be viewed x^ith special
care. Each of these compounds which is produced in sizeable-volume,
which has been implicated as having carcinogenic potential or which
has known losses of the product or the greatest potential losses through
accidents, should be evaluated as carefully as possible. Furthermore,
some compounds ranked above 57 should also be considered potential hazards,
particularly if they are produced at higher volumes than some more toxic
chemicals, if they are implicated as carcinogens, or if the processes
by which they are produced are known to have sizeable waste losses of
the product.
One important observation to be noted is that only 38 (68 percent)
of the first 57 compounds have any one of the other 3 data available
and that compounds with 2, or all 3, correlated data are very few.
Thus, any scheme that can be developed for quantifying assessment of
these four data types can only be applied to a very few of the compounds
at the present time.
29
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It should also be pointed out that the accuracy of the L^50 levels
shown in Table F-6 is essentially unknown. Where LD50 data havt*T>een
obtained on the same compound in two or more testing programs the results
may or may not agree closely. This can be quickly seen by scanning the
data in Table A-l. However, in some cases the variation is relatively
great. This is shown as follows:
IOC LD50 Values,
Item No. oral-rat Ratio
51 3100/1230 2.5
70 4360/790 5.5
81 8790/2940 3.0
103 2078/886 .. .2.3
111 2020/242 8.3
116 1400/290 ' 4.8
201 580/95 6.1
308 2828/1297 2.2
The reasons for these variations (many sizable) are unknown but presumably
is related to study protocol or data processing differences. They show
that rating schemes must be viewed with caution!
Oral Toxicity (LD50. Animal Other Than Rat) (Table F-7)
Oral toxicity LD50 data are also available in which animals other
than rats were used. Data of this type up to LD50 values of 500 mg/kg
are listed in Table F-7. These are data on compounds not listed in Table
F-6, i.e., not subjected to acute oral toxicity tests using rats. The
same additional correlated data are present, but fewer of these data are
available. Similar LDLo data are found in Table F-8, not discussed.
Table F-7 compounds should be roughly comparable in potential toxic
hazard to those in Table F-6 at similar LD50 values. However, it should
be pointed out. that in some cases where LD50, oral values have been determined
on two or more animals, the results vary widely, e.g., by ratios as great
as 50/1. The following data variations cited from Table A-l illustrate
this:
IOC LD50 Values, LD50
Item No. animal Ratio
10 17 rat/3 mus 5.7/1
12 46 rat/7 rbt 6.6/1
16 340 rat/60 mus 5.7/1
22 600 rat/2850 mus 1/4.8
25 3030 rat/200 mus 15/1
41 890 rat/75 bdw 12/1
75 180 rat/900 mus 1/5
89 76 rat/165 mus 1/2.2
111G 1454 rat/861 mus 1.7/1
114 300 rat/6 mus 50/1
30
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IOC LD50 Values, LD50
Item No. animal Ratio
160 698 rat/316 mus 2/1
163 4200 rat/1122 mus 3.7/1
165 535 rat/3700 mus 1/6.9
173 268 rat/1265 mus 1/4.7
312 891 rat/2462 mus 1/2.8
314 1072 rat/330 raus 3.1/1
340 1860 rat/65 mus 29/1
368 5000 rat/316 mus 15/1
These data variations may be partly due to differences in response between
rats and mice, or as above, to test or data evaluation protocol variations.
These data comparisons certainly reinforce the conclusion that rating
'schemes must be approached cautiously. They also indicate the need for
additional, more carefully controlled tests to be done on many compounds,
using a common protocol.
Inhalation Toxicity (LC50) (Table F-9)
The inhalation data that are most reasonably grouped together (LC50)
are presented in Table F-9. They are grouped in a roughly ordered fashion.
Due to the variations in test protocols and data units comparisions must
be viewed with caution and some skepticism. These data are displayed
with the same correlated data that are in Tables F-7 and F-8. Similar
comments apply to their utility except that the relative ordering presented
is probably less likely to be accurate, as described above, than the data
in Tables F-7 and F-8. Nevertheless, it is clear that some compounds
are more toxic than others when inhaled and the relative toxicity indicated
by the rating order is probably a reasonable approximation of actual toxic
hazard.
The number of compounds in the table (28) is a relatively small percent-
age (6.7 percent) of the IOC. It is no doubt an appreciably higher percent-
age of the volatile compounds (not accounted) but still surely represents
only a minor fraction of the total. An appreciable number of the compounds
in the table do have production volume data and some emissions data.
These items should be analyzed in detail to determine which ones present
the greatest hazard potential. However, the master list of IOC should
also be reviewed to determine which volatile compounds with no'quantitative
inhalation toxicity data are produced in moderate to large volume, or
are potential carcinogens, or have other acute or chronic test data that
indicate they are moderately to highly toxic, or have quantitative emissions
data.
Also, as in the case of the oral LD50 test data, there is an obvious
need for testing using common protocols and data evaluation procedures.
Round robin testing involving several laboratories should probably be
done on selected compounds that are most likely to represent high hazard
potential, using both LC50 and LD50 routes, to determine the reproducibility
of these toxic test data and the effects of the different exposure modes.
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Mixed Toxicity Data (Table F-10)
The data presented in Table F-10 cover a wide variety of animal type,
administration route, etc. Consequently, these data cannot be rated accord-
ing to relative toxicity. They are, however, at least crude indications
of toxicity of high to moderate levels and provide additional compounds
which need further consideration.
Production Volume Data
Production volume data are listed in Tables F-ll and F-12. All IOC
(Table A-l) production volume data are presented in Table F-ll. These
data are ranked according to 1973 production in Table F-12. There are
a total (Table F-ll) of 36 compounds with production levels = 1 billion .
Ibs/yr and 102 with production levels ^ 100 million Ibs/yr. The production
levels are summarized below.
Production Level, Number of
lb/yr(a) Compounds Listed
^ 109 36
108-109 66
107-108 52
106-107 9
(a) Highest annual production listed
in Table F-ll.
The highest volume products, especially those in the first two categories
(- 100 million Ibs/yr) should be most carefully reviewed for hazard potential.
Even if these compounds are only slightly toxic, they may constitute poten-
tial hazards because of the greater opportunity that large quantities
might escape to the environment during production or use. Consequently,
all data available on these compounds should be reviewed with particular
care.
OOP EXTRACTION TABLES
There are 6 ODP extraction tables. These are discussed briefly below.
Many of the comments listed above under the IOC extraction tables also
apply to the ODP extraction tables, where the same data types are presented.
U.S. Occupational Standard (USOS) for
Concentrations in AirOrganic Dyes and
Pigments Listed Alphabetically According
to Compound (Table H-l)
The same comments apply as for the IOC. Inorganic chemicals are
also listed since these are frequently used in ODP processes in relatively
large amounts under circumstances where greater losses or human exposure
potential may exist. However, further consideration of these inorganics
is not pursued in the present study, as discussed earlier.
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Human Toxicity DataOrganic Dyes
and Pigments (Table H-2)
There are two recorded deaths, one after ingestion of an ODP intermediate
and one upon intravenous exposure to a dye. The same comments apply as
before, under IOC.
Carcinogens and Suspected Carcinogens
Organic Dyes and Pigments (Table H-3)
The discussion under the IOC extraction Table F-4 is also pertinent
here. There are 5 recognized (human) carcinogens included in Table H-
3.
Oral Toxicity (Rat)Organic Dyes and
Pigments (Tables H-4, H-5, and H-6)
LD50, oral-rat data are covered in these tables. Table F-6 is the
equivalent IOC table. Table H-4 covers ODP raw materials from Table B-
1, Table H-5 includes ODP intermediates from Table B-2 and Table H-6 covers
the actual dyes and pigments in Table B-3. There are 5 raxj materials,
15 intermediates and no dyes and pigments with LD50 values ^ 500 mg/kg.
Those compounds that also have available carcinogenic, teratogenic or
mutagenic data or production volume data are indicated in the tables.
As discussed earlier under Table F-6, those substances with commonality
of data may represent greater potential hazards. Certainly compounds
that show high acute toxicity and also shoxj carcinogenic potential and/or
relatively high production volumes are likely to pose greater toxic hazards.
33
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SECTION 8
PRIORITIZATION SCHEMES
It is known that some of the compounds in the master tables are
toxic hazardsable or likely to inflict injury or death. If, then,
they could be ranked in some way, it would be possible to start at the
top of the list and work down to some level that is assumed to be safe.
This part of the task is extremely important for it brings the other
major objective of the task into perspective. It is extremely difficult
to assess the treatment and control technology of emissions from all
production processes. However, the assessment would become much more
manageable if priority lists were available and the most hazardous compounds
could be subjected to extensive investigations. Consequently an assessment
of the various factors that might affect toxic hazard potential was
undertaken. A number of factors were identified but no method for utilizing
them in actual rating schemes was developed. This is viewed as a major
undertaking that should be pursued in a separate study. The results
of the assessment are listed at the end of this section for information
purposes.
PRIORITY OR RATING LISTS
In the absence of a formula that would allow quantitiative, or
even qualitative, evaluation of all important criteria factors, simplistic
"prioritization" or "rating" schemes were devised based solely on the
principal toxicity (LD50, LC50, carcinogenic TDLo, etc), production
volume and waste product data. These "priority" lists were presented
and discussed in Section 7 above as extraction tables. The extraction
tables that can also be viewed as "priority" lists includes one set
of tables which contain the compounds presented as a function of increasing
or decreasing quantitiative values of various key data, such as LD50,
oral-rat. "Priority rating" tables of this type include Tables F-2,
F-6, F-7, F-8, F-9, and F-12 for the IOC and Tables H-4, H-5, and H-
6 for the ODP. There are also several extraction tables in which the
compounds appear in alphabetical order since it was not possible to
attach an ordinal rating scheme to the data. Hox^ever, these tables
can still be viewed as "priority" lists, or sets of compounds that need
special consideration as a group, for example those compounds with carcino-
genic data. These "priority" lists include Tables F-3, F-4, and F-5
for the IOC and Tables H-2 and H-3 for the ODP. Discussions of the
reasons for choosing these particular methods of "prioritizing" or "rating"
the chemicals in terms of toxic hazard potential have already been presented
in Section 7.
34
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The "prioritized" lists described above, and in Section 7, provide
a set of tools useful in providing preliminary analysis of the relative
toxic hazard posed by a considerable number of the IOC (probably about
50 to 70 percent of the IOC in Table A-l). Table A-l Addendum could
be treated similarly, although time limitations did not allow this on
the present study. The various lists can be compared with one another
to determine commonality. Of cource this has already been done to a
considerable extent in terms of comparing carcinogenic potential and
production volumes with the various acute toxicity data by including
correlated data on single lists (Tables F-5 through F-10 and H-4 through
H-6). However most of the extraction lists show only minor overlap
of the IOC, thus reflecting the manner in which they were constructed
(i.e., for the most part including only compounds which had not been
already covered by a prior selection process, on each new table assembled).
Consequently the set of "priority rating " lists (tables) represents
a number of different ranked sets that are each fairly unique in terms
of compounds included but which are sufficiently different in ranking
method as to make reordering into a master list of ranked compounds
very difficult. Fusion of the separate lists into one master list can
only be accomplished by assigning some sort of unifying weighting factors
to each data component in each of the tables. It is not clear at the
present time how this can be accomplished objectively and accurately.
Consequently each of the lists must be viewed at present as a separate
entity. The selection of compounds for further study cannot yet be
done in such a way as to readily and objectively provide a single prioritized
set of compounds for action. Nevertheless the "priority" lists as a
whole do provide a means of selecting several sets of study candidates,
mostly in some approximate order of importance, to meet such given specific
objectives. Once lists of study candidates have been identified it
may be possible, at least in some cases,, to develop a unified list,
or a reduced number of lists, through fresh analysis based on well defined
objectives and possibly additional data for background information.
EPA PRIORITY LISTS
An attempt was made to identify as many EPA priority lists of organic
chemicals as possible. Six (6) lists which resulted form this effort
are included in Appendix G. They were placed between the Appendices
for IOC and ODP "priority" lists for ease of comparison, especially .
with the IOC lists. The lists produced are presented in the following
tables:
Table G-l. Effluent Guidelines Priority List (IOC - Phase 1)
Table G-2. Effluent Guidelines Priority List (IOC - Phase 2)
Table G-3. Water Quality Planning and Standards Consent
Decree List
Table G-4. Potentially Significant Air Toxicants from the
Office of Air Quality Planning and Standards
(OAQPS)
35
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Table G-6. List of Potentially Hazardous Waste Materials
(reference 17)
Table G-7. Spills List of Potentially Hazardous Substances.
Table G-5 .is a comparison list showing commonality of compounds on the
present study "priority" lists (Tables F-4 through F-10) and' the chief
EPA priority lists of interest (Tables G-l through G-4).
The EPA priority lists are for the most part described adequately
by the table titles. The first 4 lists are considered to be the most
pertinent and will be given special attention. The effluent guidelines
lists (Tables G-l and G-2) are taken from reference 18. Twenty (20)
of the 21 entries in Table G-l and 16 of the 19 entries-in Table G-
2 are represented on either Table A-l (IOC), or one of the other master
tables, of this study. Most of these representatives are IOC. The
water quality planning and standards consent decree list (Table G-3)
contains 66 individual entries with all but 3 of them (these 3 are mixed
ethers, trichlorophenols and chlorinated cresols) specific compounds.
Thirteen (13) of these 66 entries (blanks) are not represented on the
present study master tables. This EPA priority list is the result of
the so-called 65 toxic pollutants (both individual compounds and mixtures
of compounds, or general classes of substances) that resulted from the
recent court settlement (19) between the EPA and several environmental
groups concerning implementation of best available technology (BAT)
standards by June 30, 1983. The fourth EPA priority list (Table G-
4) contains 22 entries, only one of which (a plasticizer) is not on
the master tables. Thus these first 4 EPA priority.lists are concerned
with the IOC, ODP, and related substances that are presently being considered
for effluents and emissions pollution control studies (e.g., Effluents
Guidelines BAT standards and new source performance standards studies).
Overall, commonality with master table entries (IOC, IOC Addendum and
ODP) is very high. Most EPA list entries not included in the present
study are insecticides, herbicices, plasticizers, etc, i.e., compounds
that fall outside the scope of this task.
The last two EPA lists (Tables G-6 and G-7) are additional lists
of potentially hazardous chemicals presented here for use in future
studies of the toxic hazard posed by IOC. Table G-6 covers an earlier
list of potentially hazardous materials developed by Booz-Allen, Inc.
for EPA in 1973 (17). Table G-7 is the EPA spills list of substances
potentially hazardous to the aquatic environment recently published
in the Federal Register (6). Due to time constraints they will not
be further discussed in this report.
COMPARISON OF THIS STUDY "PRIORITY"
LISTS AND EPA PRIORITY LISTS
The first 4 EPA priority lists discussed above (Tables G-l through
G-4) were compared with this study "priority" lists (Tables F-4 through
F-10) for commonality of the IOC. All compounds listed on 5 of 7 "priority"
tables were comparison candidates. However not all the IOC on 2 of
36
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the "priority" lists were candidates. Thus, only compounds with LD50
- 500 mg/kg (57 items) were covered from Table F-6 and only compounds
with LC50 ^ 1000 ppm or ^ 200 mg/m3 (15 items, 1 through 16, item 13
excluded) were covered from Table F-9. There are a total of 161 different
IOC (38.5 percent of 418 total IOC) meeting this comparison candidate
criterion on the 7 tables. The results of the comparison are presented
in Table G-5 with the data displayed to show the occurrence of this
study "priority" list IOC considered to pose a potential toxic hazard,
on each of the 4 EPA priority lists. The addendum IOC (Table A-3) and
the ODP were not included in this analysis because of lack of time.
There are a total of 46 compounds (28.5 percent of the 161 candidates)
common to the 4 EPA lists. The occurrence of an IOC compound on one
of the EPA lists is indicated by an X, 2X or 3X with the numerals referring
to the number of present study "priority" .lists containing the IOC compound.
Eleven (11) IOC (item numbers 3, 17, 30, 39, 86, 101, 227, 243, 265,
284, and 331 show multiple commonality on the EPA priority lists, with
all but 2 of them (243 and 284) also showing multiple commonality on
present study "priority" lists. The 9 IOC showing multiple commonality
on both sets of lists should be given close consideration for further
studies.
An accounting of the IOC appearing on the EPA lists shows the following:
Number of These
Total IOC IOC on Present Percent
Entries Study "Priority" List Commonality
Table G-l 25 14 55
Table G-2 21 11 '52
Table G-3 62 21 34
Table G-4 22 14 64
This tabulation shows the number of the IOC which are on one or more
the 7 "priority" lists that also appear on the EPA priority lists (Tables
G-l through G-4), in comparison to the total number of IOC on each EPA
list (commonality of EPA priority lists with present study master tables) .
The degree of commonality ranges from 34 percent for the. Consent Decree
list to a relatively high 64 percent for the OAQPS priority list. Presumably
those IOC common to both sets of lists are worthy of closer scruting
in terms of setting priorities on which compounds should be emphasized
in future effluent or emissions studies, with the compounds showing
multiple commonality as described above receiving the greatest emphasis.
Of course, there are also compounds on the "priority" lists developed
on this study x^hich are not on the EPA priority lists that are probably
equally good candidates for early studies (cf Sections 7 and 8 discussions).
Further analysis, beyond that possible on the present task, will be
required to properly set future study priorities.
COMPARISON OF U.S. OCCUPATIONAL .STANDARDS
(USDS) WITH USSR WORKPLACE STANDARDS
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Workplace standards have been established by the Soviet government
(20) for 457 chemical substances. These standards are the Soviet equivalent
of our USDS. They are reproduced in Appendix I, (Table 1-2). These values
may be of special interest since there is some indication that they were
determined by the experimental use of human volunteers. This is based
on a private communication from NIOSH (21) and is partially substantiated
by an attachment to a copy of the original Russian article, which was
hand carried to the United States by a former NIOSH employee. The attachment,
although not part of the article, refers to principles and procedures
for developing data for industrial air limits from human subject.
Efforts to determine whether human testing was in fact used to establish
the Soviet standards should continue for two reasons. Firstly, these
standards are set at lower exposure levels than the U.S. equivalents in
78 of 84 total comparisons, usually by substantial amounts (Table 1-1).
Consequently the Soviet standards may be leading indicators concerning
which of our USDS are candidates for lower exposure level standards.
Secondly, if the Soviet standards were actually established by controlled
human testing, they may represent some of the best toxic hazard data avail-
able, concerning a large set of organic compounds, that were determined
using a common well controlled test protocol. Furthermore they should
represent realistic human exposure levels for avoidance of acute toxicity
effects (chronic effects are very likely not accounted for).
PRELIMINARY ATTEMPTS TO ESTABLISH
RATING CRITERIA
The information most pertinent for evaluating the hazard of each
IOC is, of course, the toxicity data. However, the amount of IOC produced
must also be considered as well as the use that is to be made of the chemi-
cal. For if only limited amounts of a very toxic chemical are produced,
the hazard to the population might be much less than a moderately toxic
chemical produced on a large scale. The same applies to the uses to which
a chemical is put. If the use of a moderately toxic substance is such
that a large number of people will be exposed to it, this is much worse
than even a highly toxic compound that is, for example, used entirely
captively or is completely consumed as an intermediate and not an end
product. For example much HCN and acetone cyanohydrin production meets-
these criteria (i.e., used captively) and will constitute a problem only
if there are losses occurring during production.
Toxicity Data Pitfalls
The gathering of data is not always a straightforward process, espe-
cially when it is necessary to use secondary sources because of time con-
straints. The use of secondary sources introduces the possibilities of
inaccurate recording and in some cases even two closely related secondary
sources do not agree on the information contained in a primary source.
This can be best demonstrated with a concrete example. Thus reference
3 gives the following entry under acetamide:
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TXDS:orl-rat TDLo: 456 gm/kg/52WC TFXrCAR from
reference TXAPA9 14,163,69.
However, reference 9 gives the following entry under acetamide:
TXDS:orl-rat TDLo: 360 mg/kg/52W TFX:CAR from
reference TXAPA9 14,163,69; the same reference
as above.
.
The question arises as to which one is correct, since they are obviously
not equivalent doses.
The reference used in the above examples (22) was consulted and
it was. found that neither of the indicated doses could'be directly confirmed.
The dose was indicated in the following way: ". . .administration of
2.5% acetamide in the diet of rats for 12 months led to malignant liver
tumors after 12-15 months of observation in approximately 50% of the
animals at risk." There is no place in the article that describes how
much acetamide "2.5% acetamide in the diet" is. All doses are given
in percentage of the diet and the amount of diet consumed by the rats
is not indicated. It was then determined that when animal food intake
is not specified, it is assumed by NIOSH (reference 3, page xxi) that
rats .eat 15 gm/day.. Based on this assumption and the average weight
of the rats over the 52 week study period it can be calculated that
456 gm/kg is the approximate amount of acetamide administered. Thus
the datum reported in reference 2 is correct but the datum in reference
4 is grossly inaccurate, indicating that acetamide is a potent hepatic
carcinogen in the rat while in fact being a very weak carcinogen.
Data Unavailability
Inaccurate data may be worse than no data, but there is much information
that is given in an incomplete form or not available at all. For example,
total production figures for many important compounds are not available.
Some of these numbers are considered proprietary, others have never
been sought, and still others are available only for certain years.
The'problems with toxicity data are even greater. LD-50 data for oral
toxicity in rats are available for approximately 50 percent of the compounds
in Table A-l, and this is the most abundant single kind of toxicity
data available. The gaps are enormous and it may be that some of the
most hazardous compounds have never been tested.
Some of the toxicity data is subjective or descriptive rather than
quantitative.- This information can be valuable, but comparisons among
different compounds are very difficult with this kind of information.
Tentative Criteria for Use in the
Identification and Priority Listing
of Hazardous Industrial Organic Chemicals
The problems mentioned above have a direct bearing on the identif-
fication of hazardous compounds. It is necessary to identify which criteria
will be used to determine if a compound is hazardous. It is also necessary
39
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to establish if one criterion is more important than another.
Various criteria are listed below that might be considered for use in
the identification and priority listing of hazardous industrial organic
chemicals. These tentative criteria are the result of consideration
of several sources of discussions of toxicity data (15) or the potential
toxic hazards posed by chemicals (23-26).
I. NATURE OF TOXICITY INFORMATION
A. Testing Protocols Used
1. Chemical delivery
a. Species of animal used
b. Exposure or administration route
(1) oral ingestion
(2) inhalation
(3) skin absorption
(4) parenteral
(5) subcutaneous
(6) other ...
c. Rate and duration of exposure
d. Level of exposure
2. Kind of toxicity
a. Acute
b. Subacute
c. Chronic
3. Specific toxicity tests
a. Carcinogenic
b. Teratogenic
c. Mutagenic
d. Others
B. Physiological-Toxic Compound Interfaction Factors
1. Factors affecting translocation
a. Lipid versus water solubility
(1) partition coefficients
(2) ionization factors
b. Membrane mobility '
2. Biotransformation
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a. Metabolism
(1) detoxification (metabolism and exretion)
(2) formation of toxic metabolites
3. Chemical interactions
a. Synergistic (potentiation) effects
b. Additive effects
c. Antagonistic effects
II. COMPOUND PHYSICAL PROPERTIES
.A. Volatility . .
1. Boiling point
2. Vapor pressure
B. Solubility ...
1. Water
2. Aqueous/organic partition coefficients
3. Lipid (oil)
III. CHEMICAL PRODUCTION FACTORS
A. Production Volume
B. Process Type
1. Continuous
2. Batch
3. Aqueous versus nonaqueous
4. Toxic by-products
C. Process Losses
1. Amount
2. Source type
a. Continuous
b. Intermittent (upset conditions, spills, etc)
3. Escape route
a. Air
b. Water
c. Particulates
d. Solids or sludges
D.' Process Controls
E. Waste Disposal Practices
F. Demographic Factors
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IV. USES
A. Downstream Production Processes
B. End Products
1. Level of contamination with chemicals
2. Persistence of chemicals in products and
in the environment
a. Loss mode
b. Loss rate
Admittedly, all of this information is probably not available for
even one compound; but even if it were, the task of identifying hazardous
industrial organic chemicals would still exist. The task ahead then
is to determine which are the most important criteria, whether the criteria
will give a yes-no answer, and at what level a substance xvill be considered
hazardous where quantitative data are involved.
Because of the limited amount of data available for any given industrial
organic chemical and the poor overlap of different types of data, and
the difficult, time-consuming nature of this subtask, it was not possible
to choose criteria and set arbitary cutoff values. Further analysis
of this problem and the type of information available may provide some
criteria in future studies.
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SECTION 9
POLLUTION CONTROL TECHNOLOGY
Published EPA studies are concerned with control of effluents or
emissions in a general way, with little information available on control
of specific compounds". The few exceptions" concern some studies on emissions
from specific processes (described below). Because of the numerous
products/processes involved in the IOC/ODP industries, only a general
survey of control technologies was possible. Effluent controls are
discussed first, followed by emissions control technology.
EFFLUENT POLLUTION CONTROL TECHNOLOGY
Effluent waste treatment for industrial organic chemical processes
can be conceptually divided into three phases: primary, secondary,
and tertiary (27).
In primary treatment simple separation procedures include the fol-
lowing:
(1) Screening
(2) Equalization or neutralization
(3) Oil separation
(40 Flotation or flocculation.
Then the sedimentation of dissolved or particulate waterborne wastes
can be accomplished by secondary treatments such as the following:
(1) Activated sludge
(2) Extended aeration
(3) Trickling filters
(4) Aerated lagoons
(5) Waste stabilization ponds
(6) Chemical or thermal oxidation.
These treatments convert organic wastes to inactive sediments and waste
streams which are innocuous via biological or chemical conversion.
Tertiary treatments can be applied to remove refractory contaminants.
These include such treatments as:
(1) Ammonia stripping
(2) Coagulation and precipitation
(3) Filtration and microscreening
43
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(4) Carbon absorption
(5) Disinfection
(6) Electrodialysis
(7) Ion exchange
(8) Reverse osmosis
(9) Evaporation.
Sludges produced from these treatment processes can be treated in a number
of ways. However, the treatments generally include the following:
(1) Aerobic stabilization
(2) Anaerobic digestion
(3) Lagooning
(4) Heat treatment. ... ..
Also generally usable are dewatering processes such as filter presses,
vacuum filters, centrifuges or sand-drying beds.
The most complete assessment of effluent control technologies is
contained in a recent report (18) done for the National Commission on
Water Quality. The best current technologies for treatment of effluents
are summarized as follows:
Activated carbon adsorption
Activated carbon regeneration
Activated sludge
Aerated lagoon
Aeration, biological processes
Aerobic digestion
Clarification
Dissolved air flotation
Equalization/surge storage
Filtration, dual media
Neutralization
Oil separation
Ozonation
Precipitation, coagulation and flocculation
Thickening
Trickle filtration
Vacuum filtration.
Details of the characteristics and efficiencies of these technologies
are given in that report, Appendix A, pages A-l through A-29. Applicability
and efficiencies of organic pollutant removal vary widely depending
on the chemical/process in question. Thus it is very difficult to specify
"best" technologies. However activated sludge and carbon absorption
processes appear to be especially attractive and useful technologies.
AIR POLLUTION CONTROL TECHNOLOGY
As early as 1967 reasonably adequate basic air pollution control
technology was available to the industrial organic chemical industry.
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Hearings before the Subcommittee on Air and Water Pollution of the Committee
on Public Works, March 15-18, 1967, delineated the following general controls
technologies-:
(1) Incinerators - flame and catalytic
(2) Condensation units
(3) Absorption
(4) Tight systems.
The Houdry Division of Air Products and Chemicals Inc. and Monsanto
Research Corporation have done the most in depth studies of atmospheric
(air) emissions from the petrochemical industry, Houdry under EPA Contract
No. 68-02-0255 and Monsanto Research Corporation under Contract No's.
68-02-1320 (Task 17) and 68-02-1874. Issued reports, in the Houdry series
include a four volume survey of the industry (28-31) and a six volume
series (32-37) pinpointing selected high volume organics. The four volume
series of reports surveyed 33 distinctly different processes used to produce
27 different petrochemicals chosen, according to the authors, from more than
200 petrochemicals currently in production in the United States. Many of
these products are produced by two or more processes that are substantially
different with respect to process techniques and source of air emissions.
Excluding the polymers studied, the following list of petrochemicals was
included in the study.
IOC
Item
Number Houdry Compound
3 Acetaldehyde (2 processes)
7 Acetic acid (3 processes)
8DP Acetic anhydride
17DP Acrylonitrile
18 Adipic acid
2ADD Adiponitrile (2 processes)
84 Carbon disulfide
124DP Cyclohexanone
199 Ethylene
204 Ethylene dichloride (2 processes)
221DP Ethylene oxide (2 processes)
227DP Formaldehyde (2 processes)
232DP Glycerol
243 Hydrogen cyanide
265 Maleic anhydride
"Oxo" alcohols and aldehydes
7OOP n-butanol
248DP isobutanol
223 2-ethyl hexanol
254 iso.octanol
128 n-decanol
80 n-butyraldehyde
250 isobutyraldehyde
331DP Phenol
45
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338DP Phthalic anhydride (2 processes)
268 Styrene
374DP Terephthalic acid (includes dimethyl terephthalate)
82ADD (TDI) Toluene diisocyanate (includes MDI and PAPI)
62ADD (MDI)
403 Vinyl acetate (2 processes)
404 Vinyl chloride
This list includes 23 chemicals, if "oxo" alcohols and adehydes are
considered as one, or 29 chemicals using the indicated list of 5 "oxo"
alcohols and 2 "oxo" aldehydes, and 32 processes.
A summary listing of pollution control devices found to be used
in .these very .representative processes included the following:.
(1) Incinerators (thermal and catalytic)
(2) Flares.
(3) Scrubbers (water or-organic liquid absorbent)
(4) Bag filters (bag houses)
(5) Cyclones
(6) Electrostatic precipitators.
With the addition of solid adsorption (e.g., charcoal) techniques, these
pollution control technologies, although relatively few and inherently
rather simple in concept, may be adaptable to control many of the air
pollution problems in the industrial organic chemicals industry, when
properly designed and utilized. It should be noted that these control
technologies are generally utilized as add-on controls. Better results
might be realized from in-process modifications, where applicable, or
from combinations of in-process changes plus add-on controls.
The Monsanto Source Assessment study (EPA Contract 68-02-1874)
resulted in emissions data on.at least 88 IOC. These .data have been
incorporated in the Organic Chemical Producers Data Base Program (12)
by Radian Corporation and have also been included in Table A-l. Assessment
of control technologies used in the processes represented by these emissions
data is not available at this time.
It may be more appropriate to summarize the add-on control methods
which may be applicable to the vapor and liquid-phase (droplets) air
emissions associated with the synthetic organic chemicals industry differently
as follows:
(1) Incineration
(2) Adsorption on solids
(3) Absorption by liquids
(4) Condensation (vapors only)
(5) Other methods.
Incineration
Incineration has been widely used to control hydrocarbon emissions.
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Three types of combustion are used in incinerators: flame combustion,
thermal combustion, and catalytic combustion. In all cases, an auxiliary
fuel must be added to support the combustion when dilute gas streams are
involved. A special type of incinerator is the waste heat boiler, in which
the heat from the combustion is used to generate steam.
Adsorption
Adsorption of vapors-or droplets onto a solid such as activated char-
coal or a molecular sieve is an attractive emission control method because
it permits recovery of the vapors and thus allows for by-product credits.
Absorption . . . . . . .
Absorption of vapors or droplets by a liquid reagent is a possible
control method. The scrubber effluent has to. be treated to separate the
liquid reagent, which should be recycled, from the recovered compound in
order to avoid secondary pollution problems.
Condensation
Condensation of the vapors by a cooling water condenser and/or
refrigeration may be possible, at least as a first stage method, for
some of the more concentrated"effluent gas streams.
These control methods are designed primarily for volatile organic
compounds, but some processes may emit liquid mist or solid particulates
of rather high vapor pressure (e.g., naphthalene). The add-on control
methods which may be applicable to the liquid- and solid-phase (particulates)
air emissions associated with the organic chemicals industry include
the following types of equipment:
(1) Inertial separators
(2) Wet collection devices
(3) Baghouses
(4) Electrostatic precipitators
(5) -Other collection devices.
Inertial Separators
Inertial separators are the most widely used devices for collecting
medium- and coarse-sized particulates. They operate by the principle of
imparting centrigual force to the particle to be removed from the carrier
gas stream by directing the gas in a circular path or effecting an abrupt
change in direction. Inertial separators include cyclones and mechanical
centrifugal devices.
Wet Collection Devices
Wet.collection devices use a variety of methods to wet the contaminant
particles in order to remove them from the gas stream. The particles are
removed by contact with a liquid droplet or by impingement of wetted or
47
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unwetted particles on collecting surfaces followed by their removal from the
surfaces by flushing with a liquid. Types of wet collection devices include
venturi scrubbers, mechanical scrubbers, cyclone-type scrubbers, and orifice-
type scrubbers.
Baghouses
When high collection efficiency on small particle size is required,
the most widely used method consists of separating the dust from the
carrier gas by means of a fabric filter. The fabric is usually made
into bags of tubular or envelope shape, and the entire structure housing
the bags is called a baghouse.
Electrostatic Precipitators
The electrostatic precipitator design is' based on passing a dust-
laden gas stream through a highly charged electrostatic field which
then charges the dust or smoke and causes agglomeration and precipitation
of the accumulated particles.
Other Collection Devices
Other particulate-collecting devices with limited application include
settling chambers, impingement separators, and panel filters. Settling
chambers collect particles with a sufficiently high settling velocity by the
action of gravity forces. Impingement separators are usually used to collect
mists by inertial impaction. Panel filters, similar to those used in home
furnaces, have several important industrial applications including the
collection of overspray from paint-spraying operations.
As an example of matching process groups and control approaches for the
purpose of identifying specific emission control methods, the advantages and
disadvantages of major hydrocarbon control processes are summarized below: .
ADVANTAGES AND DISADVANTAGES OF MAJOR
ORGANIC CHEMICAL CONTROL PROCESSES
Process
Adsorption
Direct Flame
Incineration
Advantages
Can recover organic chem-
icals will remove low
concentrations of organic
chemicals at low tempera-
tures; does not require
heat
Simple to operate; destroys
organics; little mainte-
nance
Disadvantages
Limited to low temperatures;
limited to low concentra-
tions; must be regenerated
with steam or by heating or
disposed of; must remove
particulates
Emits nitrogen oxides; may
require expensive heat
recovery equipment; may
emit carbon monoxide;
generally requires auxiliary
fuel (energy expenditure)
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Process
Catalytic
Incinerators
Condensation
and
Scrubbing
Advantages
Smaller than a flame unit;
uses less fuel than a
direct-flame unit; less
nitrogen oxide emissions
than a direct-flame unit
Can recover organic chem-
icals, will also remove
particulate matter; con-
ditions stream for other
control units
Disadvantages
Efficiency may decline with
time; susceptible to poisons
including particulates;
requires regular mainte- .
nance
Limited to high-concentration
of hydrocarbons; potential
disposal problem; requires
second control unit
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SECTION 10
ORGANIC DYES AND PIGMENTS INDUSTRY
BACKGROUND
No reliable statistics were found on the manufacturing capacities of
any of the companies in the U.S. organic dyes and pigments industry.
However in 1973, 23 of these companies were listed as making only dyes,
10 were listed as making only pigments and 19 were listed as making both
dyes and pigments (Table B-5).
INDUSTRY CHARACTERISTICS
The manufacture of dyes and pigments. is characterized by the use o-f
a great variety of batch reactions and a wide spectrum of both inorganic
and organic materials. The starting materials are usually relatively low
molecular weight materials which are built up in the processing to higher
molecular weight substances.
Most manufacturers of organic dyes and pigments make a large number
of individual products. The demands for individual products may be quite
disparate, with the result that a batch of one product might be made only
once a week, but batches of another product enjoying a large demand might
be made every day. Large inventories of dyes and pigments cannot be econ-
omically justified because of the high unit value placed on these substances.
Thus, in 1974, the average unit value of all organic dyes and pigments
manufactured in the U.S. was $2.44 per pound. (10) Consequently the waste
effluents from the manufacture of organic dyes and pigments vary greatly
in composition on a daily basis. This unavoidable variation creates
difficult technical problems especially in coping with the wastewater from
dyes and/or pigments plants, and sometimes in dealing with gaseous emissions
as well.
HAZARDOUS SUBSTANCES
All the chemicals used as starting materials to make dyes and pigments
are listed in Tables A-l, B-l, and B-2 together with correlated toxicity,
production process, and a limited amount of waste stream data. Some
of these chemicals show high acute or chronic toxicity. Attention should
in particular be given to all OOP substances which are either known
to be carcinogenic or which are suspected of being carcinogenic. Also
of special note are highly toxic heavy metals (especially lead and mercury)
which are often associated with dye and pigment production. These should
be rigorously excluded from the effluents. Other less toxic heavy metals
50
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such as nickel, must be held within established safe limits. Among
the organic starting materials the following substances should be given
attention as potentially hazardous materials: acenaphthene, acrylonitrile,
aniline, benzene, chlorinated hydrocarbons, chlorinated phenols, nitrobenzes,
nitrotoluenes, nitrophenols, amines (both aromatic and aliphatic), and
£-toluenesulfonic acid.
The lists of dye intermediates and dyes (Tables B-2 and B-3 respective-
ly) are very extensive. Very little toxicity data is available on these
substances, hence it will be presumed that the following types of chemicals
are likely to be hazardous:
e all amino compounds ...
nitro-substituted compounds, especially those with
one or more solubilizing groups such as -SO^H or -OH
all chlorinated compounds, especially those with
solubilizing groups such as -SO^H or -OH.
POLLUTION CONTROLS
Battelle interviewed three industry sources to determine industry's
perception of the hazards associated with effluent materials from the
manufacture of dyes and pigments. This brief survey indicated that
the industry feels it can satisfactorily cope with its pollution problems
using existing technology, although some increase in both operating
and capital costs will be necessary. No attempt at independent corroboration
of this was made because of time constraints.
Careful attention must be given to the regulation of process conditions
to avoid accidental emissions of noxious gases such as sulfur dioxide
and nitrogen oxide. Personnel must be carefully trained, well-instructed
and properly supervised in this connection. When it is necessary to
use highly toxic substances such as lead or mercury, the liquid waste
effluents must be collected separately for special treatment to prevent
contamination of large volumes of aqueous effluents. Thus, one industry
source advised Battelle thaf mercury was still required in some of their
processes, but that all the liquid wastes from such processes were segregated,
the mercury completely recovered by a proprietary system and recycled
to the processes.
Emissions Controls
One industry source indicated that it feels that virtually all
gas and vapor emissions from the manufacture of dyes and pigments can
be effectively controlled by use of appropriate control equipment such
as absorbers, scrubbers, mist eliminators, and filters for the gas streams
involved. This industry source informed Battelle that all equipment
which would result in gas and vapor emissions had been routinely purchased
with the necessary pollution control devices as an integral part of
the process equipment itself. No one type of scrubber or filter will
51
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serve for all gas and vapor emission problems; hence each piece of process
equipment must have an individual pollution control device specifically
designed to cope with the problem entailed by that piece of process
equipment.
However not all companies making dyes and pigments have installed
this type of equipment. Consequently significant emissions 'of nitrogen
oxides, halogen (chlorine and bromine) fumes, volatile organics, and
dusts still are associated with many processes.
Effluent Controls
One industry source indicated that his company believes that most
wastewater effluent hazards can be effectively controlled (except for
the highly toxic heavy metals) by a central treatment facility. An
advanced, proprietary water treatment system now being tested in full
scale operation at a plant manufacturing disperse dyes has been described
to Battelle as being very promising. The system involved differs from
that used ordinarily in respect to the employment of carbon absorption
beds for primary treatment of the effluent from the plant first enters
a large holding reservoir which serves as an "equalization" basin.
This reservoir holds a volume of effluent corresponding to about 1.5
days throughout. It serves to even out surges in the varying composition
of the plant effluent. The highly acidic effluent (containing mainly
sulfuric acid as the mineral acid component) is neutralized with lime.
The precipitated calcium sulfate, together with certain heavy metal
compounds and some insoluble salts of organic acids is removed in clarifiers.
The clear liquid passes then through beds of activated carbon which ab-
sorb all colored materials and many polar, high molecular weight organic
chemicals as well. The effluent waste has the characteristics, on the
average, shown below.
CHARACTERISTICS OF.LIQUIED EFFLUENT
FROM CARBON TREATMENT SYSTEMS
Characteristic Content, ppm
Biological oxygen demand (BOD) 350
Chemical oxygen demand (COD) 1,000
Iron 10
Nickel 1
Copper 2
Lead 1
Zinc 1
The effluent is further treated in the secondary system (activated sludge)
of a municipal sewage disposal plant.
The activated carbon beds are periodically regenerated in a furnace.
Stack gases from the furnace are passed through an afterburner and the
effluent gases scrubbed with water. The scrubbings are passed into
the equalization basin and treated along with plant wastewater.
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The solid wastes (mainly calcium sulfate and some heavy metal compounds)
are disposed of by landfill. Ideally, the calcium sulfate sludge should
be efficiently de-watered in high pressure hydraulic filters and sent
to a landfill lined xcith an impermeable (plastic) membrane. Such a landfill
should also be equipped with a system for removal and treatment of leachate
from the pit (owing to the intrusion of rainwater) to insure that there
will be no "secondary" environmental pollution by leaching of this solid
waste.
A further environmental pollution problem in the manufacture of dyes
with a significant solubility in water is much more difficult to deal
with. Such dyes must be precipitated from solution by "salting out".
This manufacturing step requires that large amounts of sodium chloride
be added to the finished dye in the reactor to precipitate it from solution.
The effluent from plants making such products therefore contains large
amounts of salt and much larger amounts of colored substances (i.e., dyes)
than are encountered in effluents from plants making organic pigments,
vat and disperse dyes. Such plants should always be located near the
ocean to avoid contamination of fresh water resources {rivers and lakes)
with salt.
One other approach to the control of hazardous organic materials
in wastewater effluents could be considered. This is the Zimmerman (Zimpro)
process, which is used by some municipal sewage disposal plants for sludge
disposal. The process depends on the fact that any organic compound can
be oxidized, even in aqueous solution, if the solution is heated to a
sufficiently high temperature (8, p 112). However such an application
of the Zimpro process might be prohibitively expensive because of the
low concentration or organic materials (1000 ppm) and the corrosive nature
of the inorganic materials present.
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SECTION 11
CONCLUSIONS
The following conclusions are warranted based on an analysis of the
central data compilations and the data extraction lists produced in this
study:
(1) A unique data base useful in the assessment
of the toxic hazard potential of industrial
organic chemicals (IOC) and organic dyes and
pigments (ODP) has been assembled.
(2) The basic compilations, which are master tables
of toxicity, production process, waste products,
production volume and end use data on 418 IOC,
115 ODP raw materials, 722 ODP intermediates, and
1458 actual dyes and pigments (Tables A-l, B-l,
B-2, B-3, and B-3 Addendum, meet an urgent EPA
need for convenient, single source availability
of detailed correlated data for identifying and
selecting groups of compounds for new source
performance standards studies, effluent guidelines
studies and the like. Also an additional 93 IOC
are presented in Table A-3 (IOC Addendum) with
some correlated toxicity and production volume
data but these addendum IOC were not further
analyzed due to time constraints and therefore
are not represented in the following conclusions
concerning the IOC.
(3) Eighteen extraction tables were assembled based
on various simple lists of toxicity data and
production volume data. These may be viexjed as
"priority" lists of compounds that should be given
special attention as candidate groups for further
study.
(4) Six IOC extraction tables (Tables F-2, F-6, F-7,
F-8, F-9, and F-12) and three ODP extraction tables
(Tables H-4, H-5, and H-6) were assembled with
the chemicals presented in order of quantitative
toxicity or production'volume data. These can be
considered approximate "priority rating" lists.
54
-------
(5) Six IOC extraction tables (Tables F-l, F-3, F-5,
F-10, and F-ll) and three OOP extraction tables
(Tables H-l, H-2, and H-3) were assembled with
the chemicals listed alphabetically. These can
be considered "priority" groups or lists.
(6) Use of the 18 "priority rating" and "priority"
lists to identify the chemicals that pose the
greatest potential hazard must be approached with
great care since the randomly collected data upon
x./hich the lists are based are essentially non-
standard protocol data of unknown accuracy. Be-
cause of this, consolidation-of the lists into one
master "priority rating" list is not possible
although one "priority" grouping of all compounds
could be assembled.
(7) Four of six EPA priority lists obtained on this
study (Tables G-l. through G-4) were considered of
primary importance and were compared with seven
of the IOC "priority rating" or "priority" lists
(Tables F-4 through F-10). The 46 IOC common to
the two sets of tables (Table G-5) constitute a
selected group of chemicals for possible further
study, with nine chemicals which show multiple
commonality (text page 41) of possible special
significance.
(8) More than 100 additional IOC which are not on the
four EPA lists but are on the present study "priority"
rating" or "priority" lists may be equally good can-
didates for further, studies.
(9) Although quantitative toxicity data are available
on 75 percent of the IOC, the most prevalent
reasonably uniform test protocol data (50 percent
of the IOC) that can be listed in order of decreas-
ing toxicity (Table F-6) are LD50, oral-rat. Fifty-
seven (13.5 percent of 418 IOC) of the IOC on this
list of 209 compounds constitute potential toxic
hazards (LD50 ^ 500 mg/kg).
(10) LD50, oral-animal other than rate data are also
available (Table F-7) on another 17 percent of
the IOC with 16 of these IOC showing LD50, oral
data = 500 mg/kg. This constitutes a ground total
of 73 IOC (17.5 percent of 418) with LD50, oral
data ^ 500 mg/kg.
(11) Inhalation data (LC50, any animal and test protocol,
Table F-9) are available on 29 IOC (7 percent of 418)
with 15 of these compounds (4 percent) posing a
55
-------
o
potential toxic hazard (LC50 ^ 1000 ppm or 200 mg/m ).
(12) Quantitative toxicity data are available on only
16 percent of the ODP intermediates and 3 percent
of the dyes and pigments. Consequently the few
compounds identified on the ODP "priority" lists
must represent a very incomplete set of potential
toxic hazards.
(13) The important lists of compounds with animal test
data indicating that they are carcinogens (Tables
F-4 and H-3) or mutagens or teratogens (Table F-5)
are presented in alphabetical order due to the great
variation in test protocols used to obtain the data.
Nevertheless there are some compounds on these lists
that are of greater concern than the rest, including
about 25 compounds that are either known human car-
cinogens, relatively potent test carcinogens (animals)
or are both carcinogens and mutagens or teratogens.
(14) Production volume data are available on 163 IOC
(39 percent of 418 IOC, Table F-ll), with quantitative
toxicity data available on 143, or 90 percent, of
these. This is a very high degree of commonality.
(15) The 102 highest production volume IOC (^ 100 x 10
Ibs/yr) should be given special attention, particular-
ly if they are on one of the toxicity "priority" lists.
IOC products with no production volume data (61 per-
cent of 418 IOC) or those few with moderate to high
production volumes but no toxicity data, are can-
didates for additional data searches or toxicity
testing.
(16) Production volumes are available on fewer ODP
products (20 percent) than on the IOC, with the
number of correlated production volume and toxicity
data very few (25 items, 1.5 percent, 16 percent
commonality),
(17) Quantitative waste product data of uncertain reliability
are available on 108 (26 percent) of the 418 IOC
(none on the ODP), including effluent data on 4
percent and emissions data on 22 percent.
(18) Ninety-five of the IOC (23 percent) have quantita-
tive end use pattern data, with most of these (about
90 percent commonality) shox^ing quantitative toxicity
data.
Additional conclusions which can be drawn include:
56
-------
C19) Definitive criteria for rating toxic hazard
potential could not be established but work
should continue on this important task.
(20) A state of the art assessment of pollution
control and waste treatment technology led to
a determination that most of the published
information on these technologies is of a
general nature. Due to wide variations in
production process technology and in the
applicabilities and efficiencies of different
techniques for Controlling organic effluents
or emissions, it was not possible to specify
"best" technologies on the present study, given
the broad scope of the program and the time and
funding available for the task.
(21) Because of the complexity of these industries
and the present state of toxicological data
availability and understanding, this study should
be viewed as a beginning effort.
57
-------
SECTION 12
RECOMMENDATIONS
An extensive analysis of the master tables of coordinated, comprehen-
sive data on industrial organic chemicals (IOC) and organic dyes and pig-
ments (ODP) and the eighteen tables of extracted data produced using this
data base has been carried out. In addition to the results and conclusions
summarized in Sections 1 and 11, a number of areas were identified where
additional analysis of the presently available data would be fruitful and
where new information of potentially great value should be sought. These
areas are summarized in the following outline:
FUTURE WORK OUTLINE .
1. Computer Storage of Data (Computer Program)
2. Expand Data Base
(a) Compounds included
(b) Identifying symbols (WIN, Chemical Abstracts)
(c) Toxicity data additions - especially common protocol
(1) Acute
(2) Chronic
(d) Process information
(1) Update present data
(2) Process information on new compound additions
(e) Waste products - quantitative data on specific compounds
(f) Production volumes
(g) Quantitative end use patterns
3. Continue Examination of Present Data Base to Identify New Extrac-
tion Modes
4. Continue Comparison of Various Extraction or "Priority" Lists
(a) Determine commonality of key data
(b) Construct more complex comparison lists
(1) Most toxic compounds - acute toxicity data
(2) Most toxic compounds - chronic toxicity data
(3) Highest production volumes
58
-------
(4) Quantitative waste product data
5. Continue Attempts to Identify the Most Important Criteria for
Determining Toxic Hazard Potential
(a) Continue analysis of the potential criteria outlined in
Section 8
(b) Evaluate the Ames Bioassay Method
(c) Determine whether potentially important criteria have
been overlooked
6. Continue Search for Pollution Control Technology and Equipment
(a) Emphasize specific compound/process technology
(b) General technology advances.
The value of the present data base can be improved by establishing
a computer program that would provide rapid access to data on the IOC
and OD? with a format that would facilitate data comparisions and allow
new data compilation arrangements to be readily assembled for manual
study. The Radian computer program (12) developed to accommodate IOC
should be amenable to modification to include the new data and IOC con-
tained in the present study. A similar program could be developed to
accommodate the OOP entries. The use of the WLN symbols would allow
searches or data compilations keyed to specific chemical structures to be
accomplished readily. These computer bases would allow more facile com-
parisons of the present "priority rating", "priority" group and EPA priority
lists, to identify commonality. Also compilation of new and more extensive
or data inclusive "priority" lists would be accomplished more readily and
efficiently. These could include:
Compounds listed according to decreasing production
volume correlated with various specific toxicity data
Compounds listed in order of toxicity data not yet
specifically analyzed (e.g., LD50, animal data
obtained by administering the chemical by routes
other than oral or inhalation)
» Compounds listed in order of total organics emissions
(quantitative data)
» More extensive compilations incorporating multiple data
types
More work needs to be done to insure that all the important data
outlined above are obtained. Potentially important sources of this
information were not utilized on the present study because of time and
funding constraints. These include the following:
Producing companies
- Product brochures
59
-------
- Annual reports
- Personal contacts
» Industry organizations
- Published reports
- Personal contacts
e Primary literature (computer searches of abstract services)
- Chemical Abstracts
- Index Medicus
- Predicasts.
Collection of information by these routes would no doubt be time consuming
but they might provide significant amounts of new and important data. Some
preliminary work using a few selected search subjects should establish the
value of these approaches.
Some additional process data which could be incorporated into the pre-
sent study-are already available in reference 12.
Even without the developmment of a computer program for storage and
retrieval of the data base developed on this study, further analysis of the
present data is possible. Thus new lists such as those outlined above
under computer studies could be manually prepared and used. These efforts
would become even more important if new data were obtained by the methods
outlined above and added to the data base. Comparison of the newer "priority"
lists with each other and with the already available lists should provide
further identification of compounds with the greatest toxic hazard potential.
Of course efforts to identify the most important criteria for evalua-
ting toxic hazard potential should be continued. Also further searches
for and assessment of pollution control equipment and technology needs.to
be carried out.
60
-------
REFERENCES
1. Industrial Organic Chemicals. Volume 6 In: Industrial Process
Profiles for Environmental Use. EPA Contract 68-02-1320, Task No. 17,
Monsanto Research Corpoation, Draft being edited by Radian Corporation,
Austin, Texas (1976).
2. Steadman, T. R.. Organic Dyes and Pigments. Volume 7 In: Industrial
Process Profiles for Environmental Use. EPA Contract No. 68-02-1323,
. Task No. 26, Battelle-Columbus, Draft being edited by Radian Corpora-
tion, Austin, Texas (1976). _ . .
3. NIOSH Registry of Toxic Effects of Chemical Substances. 1975 Edition,
U.S. Government Printing Office,
4. Sax, I. Dangerous Properties of Industrial Materials. Reinhold,
4th Edition (1975).
5. Stecher, R. G. Ed. The Merck Index of Chemicals and Drugs. 8th Edi-
tion, Merck and Company, Rahway, New Jersey (1968).
6. Code of the Federal Register. Title 29, Labor, Parts 1900-1919,
U.S. Government Printing Office, July 1, 1975.
7. Stanford Research Institute. Chemical Economics Handbook, Menlo Park,
California.
8. Standen, A. Ed. Kirk-Othmer Encyclopedia of Chemical Technology,
2nd Edition, Interscience Publishers, John Wiley and Sons, Inc.,
New York, Vols. 1-22, Supplement and Index (1972).
9. Suspected Carcinogens. Subfile of: NIOSH Registry of Toxic Effects
of Chemical Substances, 1975, U.S. Government Printing Office.
10. Synthetic Organic Chemicals, United States Production and Sales,
1973 and Preliminary'Figures 1974, United States International Trade
Commission Publication 728, U.S. Government Printing Office.
11. Chemical and Engineering News, June 7, 1976, pp 36-37.
12. Garner, D. N., and Dzierlenga, S. Organic Chemical Producers Data
Base Program, Data Base Report Generator. EPA Contract No. 68-02-1319,
Task No. 51, Radian Corporation, August 6, 1976.
13. Wilkins, G. E. End Use Patterns for Significant Organic Chemicals.
EPA Contract No. 68-02-1319, Task No. 61, Radian Corporation, July 21,
61
-------
1976.
14. Environmental Safety & Health Information. ERDA (336) April 16,
1965.
15. Loomis, T. A. Essentials of Toxicology. 2nd Edition, Lea and Feiberger,
Philadelphia, Pennsylvania, 1974, 223 pp.
16. Lowenheim, F. and Moran M. Eds. Faith, Keyes and Clark's Industrial
Chemicals. 4th Edition, Wiley-Interscience, New York, 1975.
17. Johnson, H. A Study of Hazardous Waste Materials, Hazardous Effects
and Disposal Methods. Vol. I. EPA 670/2-73-14, 1973, 406 pp.
18. Catalytic Inc. Capabilities and Costs of Technology for the Organic
Chemicals Industry to Achieve the Effluent Limitation of P.L. 92-500.
PB 244544, National Commission on Water Quality, June 1975.
19. EPA Proposes Setting Toxic Restrictions as Part of BAT Guidelines.
In: Toxic Materials News, D. R. Newman, Ed., Washington, D.C., 3
(8), April 15, 1976, pp 59-60.
20. Maximum Permissible Concentrations of Harmful Compounds in Working-
Area Atmosphere.. Zdravookhraneniye SSSR, 1970, 18 pp (Translated
by D. K. Dreyer, Battelle-Columbus).
21. Haas, B. National Institute of Occupational Safety and Health,
5555 Ridge Road, Cincinnati, Ohio 45268.
22. Weisburger, J. H., Yamamoto, R. S., Glass, R. M., and Frankel, H. H.
Prevention by Arginine Glutamate of the Carcinogenicity of Acetamide
In Rats. Toxicology and Applied Pharmacology, 14, 1969, pp 163-175.
23. Principles for Evaluating Chemicals in the Environment. National
Academy of Sciences, .Printing and Publishing Office, 2101 Constitution
Avenue, N.W., Washington, D.C. 20418, 1975, 454 pp.
24. Lowrance, W. R. Of Acceptable Risk, Science and the Determination of
Safety. William Kaufmann Inc., Los Altos, California, 1976, ISO pp.
25. Harper, K. Toxic Hazard, The Evaluative Process. In: Chemistry
in Britain, 12, 99-101, March 1976.
26. Geiss, F., and Bourdeau. ECDIN, An EC Data Bank for Environmental
Chemicals. In: Environmental Quality and Safety, Global Aspects of
. Chemistry, Toxicology and Technology As Applied to the Environment.
Academic Press, New York, 5, 1976, pp 15-24.
27. Sittig, M. . Pollution Control in the Organic Chemical Industry.
Noyes Data Corporation, Park Ridge, New Jersey, 1974, 305 pp.
62
-------
28. Pervier, J. W., et al. Survey Reports on Atompsheric Emissions from
the Petrochemical Industry, Volume I. EPA 450/3-73-005a, Air Products
and Chemicals, Inc., Houdry Division, Marcus Hook, Pennsylvania,
March 1974, 261 pp.
29. ' Ibid, Volume II, EPA 450/3-73-005b, April 1974, 332 pp.
30. Ibid, Volume III, EPA 450/3-73-005, April 1974, 261 pp.
31. Ibid, Volume IV, EPA 450/3-73-005, April 1974, 287 pp.
32. Schwartz, W. A., et al. Acrylonitrile Manufacture. Volume 2 In:
Engineering and Cost Study of Air Pollution Control for the Petro-
chemical Industry. EPA 450/3-73-006b, Air Products and Chemicals
Inc.,' Houdry Division, Marcus Hook, Pennsylvania, February 1975,
103 pp.
33. Ibid. Ethylene Dichloride Manufacture by Oxychlorination. Volume 3.
EPA 450/3-73-006c, 1975.
34. Morris, R. B. Ibid. Formaldehyde Manufacture with the Silver Oxide
Process. Volume 4. EPA 450/3-73-006d, March 1975, 94 pp.
35. Ibid. Formaldehyde Manufacture with the Mixed Oxide Catalyst Process.
Volume 5. EPA 450/3-73-006e, March 1975, 82 pp.
36. Field, D. E., et al. Ibid. Ethylene Oxide Manufacture by Direct
Oxidation of Ethylene. Volume 6. EPA 450/3-73-006f, June 1975, '
97 pp.
37. Schwartz, W. A., et al. Ibid. Phthalic Anhydride Manufacture from
Ortho-Xylene. Volume 7. EPA 450/3-73-006g, July 1975, 108 pp.
63
-------
APPENDIX A
INDUSTRIAL ORGANIC CHEMICALS-TOXICITY
PRODUCTION, WASTE AND USE DATA
-------
A-l
TA!it£ A-L. INDUSTRIAL. OKCANIC ailiUHUM.S-TOXlCITY,
1 1 cm
r? c.,
Cir.ii|>oimJ
N;V.nc jin-.l
,^,tl_
Cli.-ui. Ai'dtr.
Ki-T.lstry t'.o. Oral luxlclty, T.":K: ll.ir.ir>! K.:l Im;
4
OOOO^J3-'9 - - - Skn anil nuic nom " TULo:600 gm/kK/Y
(L 5uo LA L irr, NKO ' TF?C:SEOf skn-oma
Acctnl 000105577
(ACftnlhyJc. iltcthyl (20Y02)
accul)
4S70 orl-rat
L)LIil-l L)U
llii-2 ili'l-2
N.'ircuclc, b;idcd on
I.i".ii: iOOO pp:r./4ll,
IM-rat
3
DP
AcotnldctiyJe
ClIjCKO
000075070
(VIII)
1930 orl-rat
1232 orl-nus
L)irr-3 L)lrr-l
ihl-3
S)iny-2
ihl-2
ihl-2
TCLo:134 nnn,
TfX:IRR. Ihl-hmn
L Irr, CNS
narcotic
LDLo: 500 r.g/kg,
ipr-rat
LCI.o: 4000 ppn/4H,
Ihl-rat
IJ150: 640 eg/kg.
scu-rat
LD50: 560 mg/kg.
USOS air: TVA
200 ppra or
360 tng/a3
Acetaldol 000107891
(Butyraldehyde, 3-Kydroxy) (ViilVQ)
CH3CK(OH)CH2Ci:0
2180 orl-rat
L)irr-2 L)U
ing-2 S)U
ihl-2
Acute oral
LD50: 140 eg/kg,
skn-rat
Acetanide
CHjCOMH.,
(CjHjXO)
Acetanillde
CH.CO:.HC,K,
J o 5
(CgMjSO)
000060355
(ZV1R)
000103844
(1VNX)
30g/kg orl-rat
800 orl-rat
1210 orl-mus
Details I'nkr.ovn
(Low Toxicity)
L)alr-l L)alr-l
S)tng-2 S)ing-2
ihl-1 ihl-2
Mild irr, low
toxlcity
LD50: 10 eg/kg.
scu-rat
LD50: 8300 eg/kg,
scu-aus
Cyanosis, derma-
titis
LDLo: 1000 Eg/kg,
ipr-ctus
TDLo:456 ga/kg/
52WC
TFX.'CAR. orl-rat
Acetic acid
CHjCOOH
000064197 3310 orl-rat L)lrr-3 l)irr-2 TDLo:1470 ug/kg,
(QV1) 4960 orl-mus lng-3 S)U TFX:CIT, orl-liajn
Wlo: 1200 ihl-2 Tm.o: Rift pom/3a,
orl-rbt S)U ihl-han. TFX:IRR
Burns, lacrymitions,
. . conjunctivitis,
dcrnatttls
LC50: 5620 ppm/111,
Itil-nus
USDS air:
TVA 10 ppm
or 25 3ig/m3
-------
niocKss, HASTE, rsooucmoN ANI> i!::r, urn
Sourrrs ol
Process
No.
Wnsti-
Ttv.-itr..-
Total
Pr.Hlu.-t i.-
Kr fi-n
tar, li£lit
cycle oils, drlp-
oils, ivfornuir
bottoms
197 Separation
Dye Int; ph.irm;
1)6-669
3)348
6)1
AcctulJetiyJe-ethanol 113 Condensation
Ethylene, oxygen,
air
73
Oxidation
(Hydration)
Echanol
Propane-rich LPG
propane, air,
xoncaldehyde, vater
Acetaldehyde, dilute
alkali
114
212
74
V'acker Process
(Oxidation)
Oxidation
Condensation
Ethyl acetate,
aqueous ainsonla
Aniline, acetic acid,
benzene (solv)
118
13
Anmonolysls
Acetylation
Acetaldehyde, ethyl
acetate, air
90
Oxidation
Methanol, carbon
Bonoxidc
192
Carbonylatlon
n-butanc & other
^Ufcht hydrocarbons;
211
Oxidation
etlianol, accutl, aciJ
or suit catalyst
Air: ethane (4.4 r>/ton)
ethylcne (54.7 f/ton)
acutnldchydc, methane
methyl chloride
(17.3 ?/ton)
Water: discharge 1,200
gallons/ton containing
chlorinated aldehydes,
also catalyst metals &
acid. See 1)5-249
Air; CO (27 MM if per yr)
acetaldehyde, ethanol
ethyl acetate. See
1)6-363
Chiefly forruldehyde &
various aldehydes, alco-
hols & acetone
Water: acetaldehyde,
acctaldol, NaOH
ScruSbcr vent
to flare
657.2
(1447.6)-
1972
Air & Water: reactants
& products
Benzene
1.6
(4.0)-
1973
1104
(2429)-
1973
1033.7
(2580)-
1974
954
(2100)-
1975
Air; hydrogen (11 5/ton) Off-gas
CO (403 f/ton), methane scrubber
(25.5 J/ton), mathanol vent
(29.8 5/ton)
Vntcr : 885 of waste
(507. proplonlc & 507.
higher org)/con
50 g.illons/tun total
.i c IT; acetic acid,
alcotiol, al('<:liyd*:s,
kcto>i':.i, ostcrn, acidc
ctlicrn
At r ; Lutnne, propone,
ethnna
inj, buiUEing inil, pack-
or.i'1^, l'*:trolcuta ind, solv,
cu$ti:ct ics , or& syn, por-
furaes, flavors, electrical
ind, appliaticcR, Rvichincs,
consumer ind
Syn: 50~ acetic acid and
anhydride, UZ n-batar.ol,
lit 2-et!iyl hcxunol, 25:1
olsc: peracetic acid, pen-
taerythrltol, pyrltlir.es,
chloral, l,3-butylc:;e gly-
col, trlncthylolprcp.lr.e,
themoscttins resins; rbr
accelerators 4 ar.cloxidants,
preservative for fruit &
fish; in fuels; hardeners
1)6-359
2)2
3)348
6)1-105
1)6-247
2)2
3)348
6)601A
7)1-92
1)6-363
1)6-723
1)6-251
2)255
3)364
Rbr accelerators; age re-
sistors; syn; perfumery;
engraving; ore flotation;
solv; solv oixture for
cellulose acetate; fungi-
cides; org syn; printer's
rollers; cadaiua plating;
dyes; drugs; dyeing assis-
tant; syn polyners
Org syn (reactant, solv, 1)6-371
peroxide stabilizer); gen- 2)3
eral solv; laco; explosives; 3)349
soldering flux; hygroscopic 31'.
ngn; wetting agn; penetra-
ting agn
Rbr accelerator; Inhib la 1)6-79
hydrogen peroxide; stabi- 2)9
lizer for cellulose ester 3)349
coatings; ofr of iat (para-
nltroaniline, paranitro-
acetanilide, parahcxylene-
diacnine); syn camphor; pharm
chcn; dyestuffs; precursor
in pencillan ofr; aedlclne
(antiseptic)
Hfr: 40Z vinyl acetate, 23J 1)6-293
cellulose acetate, 12Z ace- 2)12
tate esters, 10Z TPA/D.'iT, 31 3)350
textile processing, 2.5Z 6)60L\
chloroacetic acid. 9.5^ nisc: ^1)35
pham; dyes;' insec, photo
Chen, etc; food additive (as
vinegar); natural latex coag-
ulant; oil-veil acidlzer;
textile printing
1)6-645
1)5-715
-------
TAHLK A-l. ((\niclinu.-i!)
Itca Nn.-ac nntl
Vot Ki-rn-uln
8 Acetic uni'.vdrlda
t>P (CM.CO)^O
, *
403
it
Clio:n. Al>«tr.
Registry No.
(«N)
00010S247
(1VOV1)
ti
Ovil Toxtelty, Toxic Hi
Ll),0. W,l '*£ .\i-iiU'
17SO orl-rnt L)lrr-3
l"«-3
ill 1-2
S)U
ii it
:i Til I'd K;lt I til1
Cliroi'.lc
L)lrv-2
S)U
"
ToxK-olot;v Tl.V Curflnovun^B
Irr, corrosive to USOS nlr: --
cyoa ft upper rcb- TCA 5 ppm
plratory tract. Or 20 tig/m3
Ocrnacitls on con-
tinued contact vlth
skn
LCI.o: 1000 ppn/41(,
Ihl-ra; . "
9 Acetone
DP Clt.COCH.
000067641
(1V1)
5300 orl-rbc
LDLo: 8000
orl-dog
L)lrr-l
lng-2
ihl-2
S)lni;-2
ihl-2
skn
ab3-2
L)irr-l
S)inf-l
ihl-1
skn
abi-1
TCI.o:5;0 ppn
TFX:eye. ihl-tan
TCI.o: 12,000 ppo/
«K. TFXrCSS. Ihl-h
Karcoclc In
conccn
USOS air:
T.>'A 1000 ppa
or 2400 ng/n3
10 Acetone cyanohydrln 000075865
(Laetontrile, 2- (QXCK)
methyl)
17 orl-rat
3 orl-tnus
14 orl-rbt
9 orl-gpg
L)lrr-l L)0
S)lns-3 S)U
ihl-3
skn
abs-2
LCLo: 63 p?a/«H,
Ihl-ra:
LDLo: 3500 tg/ke.
scu-rct
1.C50: 575 ppm/2H,
Ihl-nus
LD50: 17 ng/kg,
skn-rbt
11
Accconlcrile
000075058
(NCI)
3800 orl-rat
L)lrr-l
S)ins-3
lhl-3
skn
abs-3
S)lng-l
lhl-1
Highly toxic
(cyanide)
LCLo: 3000 ppo/ill,
Ihl-rat
LD50: 1920 Eg/kg,
Ipr-nua
LDLo: 700 eg/kg,
8CU-OU3
USOS air: TWA
40 ppn or
70 ng/a3
12. Acetophenone
CH,COC,H.
J 0 J
(CBHB0)
000092802
(1VR)
900 orl-rac
-------
Sources of Process
COt!l[VlU\J . JiO.
ActUldoliy.lc, ethyl 90
acctntc, aL?
Acetic iicld 9V\
'
Acottc oclJ 94B
Beazcnc
Cuacnc, air 33
hydrogen, sodium
carbonate, sodiua
hydroxide, sulfuric
acid
62! synthetic
acetone (563 m kg)
produced by this
process in 1973
211
Acrolein- 234B
2-propanol
212
*ropanol 257A
.
2-propanol- 257B
ait
Proci'ss
OxUlatlcn
Pyrolysis
Pyrolysis
Oxidation and
Cleavage
(Peroxidatlon)
(See acetic -
acid above)
Hydrogen
transfer
(See ac«tal-
dehyde above)
Oxidaticn
(Dehydrogena-
tioa)
Oxidation
(Dehydrogena-
'tion)
AssociaU'll UjKti:
Wnstt-.^ Tri'nliii.-iu
fpli-alrn fnrtors (process
94): CO - 3.S.;!, nchylciif -
13.6, ni-tlian.-. - 10.:', pro-
pan? - 2.C, pcopndicne -
2.3, acetic .inhyilrlile - 1.0,
ethane - 0.^, acetic acid -
0.3, particular - 0.01
Atr: cicthanc, cthylonc, . Ncrnnlly burni'.d
& kctonc also gas scrub-
ber systcn
Vater: sodium livcroxide Koavv cadi also
& eodiir-i acetate burned
As above with the
addition of benzene
Host vatcr is recycled, Sluige is inctn-
scrub water contains: eratcd
cumene(trace); acetone
(.91 '?/ton phenol);
phenol (0.15 iVton
phenol), acctophenone.
a-methylstyrene
(See acetic acid above)
(See acetalcehyde above)
Water: acetone. 2-pro- Absorber
panol
Air; acetone, 2-propanol
vapors
Total
Product ion
758.?
(1670.0)-
1973
800
(1760)-
1974
651
(1520)-
1975
t.
904
n QflQ^-
\i.'07 J
1973
900
(1980)-
1974
723
(1591)-
1975
ii
11
" .
ii
Use* R«'ftTi'nceH
95: cellulose acetate 1)6-291
fibers 4 plnsclcs; vtnyl 3)2'
acetate; dehydrating t. 3)350
acetylatlng av;n la produc- 5)559
tion of pharu, dyes, per- 12)
furces. explosives, etc; 13)27
aspirin
11 1)6-305
6)601A
11)36
1)6-309
Sj-n; 25- r.ethyl ncthacry- 1)6-125
late, 14% tr.Cfchyl iso- 2)30
butylkotor.e, 10 coatings 3)352
solv, 61 pharn, 5" cheoi- 5)559
cal processing solv, 4.7Z 6)6013
bisphenol A, 4.7Z cellulose 11)36
acetate spinning solv, 2.61 13)27
hexylene glycol, 2.51 di-
acetone alcohol, 2.3- r.ethyl
isobutyl carblnol. 1.81 iso-
phorone, 0.6:' cesityl oxide.
disc; to clean & dry parts
of precision equipment; solv
for potassiua iodine &
permanganate ; delusteranc 1)6-719
for cellulose acetate
fibers
1)6-791
11 1)6-723
1)6-853
" 1)6-357
Cinnene hydroperor.ide 279A
sulfuric acid 2798
Acetone-hydrogen
cyanide
165
Cleavage
Addition
(Condensation)
Vater; acetone (0.46kg/
Hg), phenol (0.08 kg/Mg
phenol), mesityl oxide
(19.9 kg/Mg phenol)
Air; hydrogen (15g/Xg
phenol), CO (20g/Kg phe-
nol), phenol (1.4Skg/Mg)
Emission factors:
HCN - 1.0, acetone - 1.0
245.2
(540)-1959
Syn: 832 methyl meth-
acrylate, V7. higher
aethacrylates
1)6-915
1)6-525
2)674
3)352
12)
13)27
Propylenc, air
acaonla, culfurlc
acid
258
Aramoxtdation
Air: acrylonitrile
(5kg/:tg product), CO
(200kg/:!g), propane
(50kg/Mg), propylene
(100 kg/Mg) , KCtt (1 kg/
Hg produce)
Water: arauonlua sulfate,
ftcetoaitrllo
Absorber 68.1 Solv In hydrocarbon pro- 1)6-859
off-gases to (149.9)- cesses, especially £or 2)30
flare 1973 butadiene; specialty solv; 3)917
intj separation of fatty 5)559
acida from vegctnble oils; 12)
nfr of syn pharo
Ethylbcnzeno, air,
sodiun hydroxide,
manganese acetate
fetlc anhydride
Oxidation
30,
9f>
33
Frlodcl-Crafts
Reaction
(Seo ncc-tone
above)
Air; ethylbcnzcnc, ace-
tophonone, o-phcnylethyl
alcohol
Water: sodiua salts of
byproduct add.*, uodium
hydroxide, cthylbonsene,
ncctophcnunc, a-plictv/1-
ethyl alcohol
Air & W.iti-r; HC1 , ben- Scrubbers;
zene, acetic anhydride, H.'jovy ottd
acetic acid incinerated
1.0
(2.2)-
1973
1.22
(2.68)-
1°74
Perfumery; solv; Int for
phnrm, resins, etc;
flavoring
1)6-47
2)32
3)1018
4)8
12)
1)6-117
1)6-313
1)6-125
-------
TAIU.i: A-l. (Conl
I torn
No,
13
'CoOfVMj
NHIUO nnd
Kormnln
Acetylene
lic:cn
(C2H2)
(.'lieu. A'.-str.
Rcj; tstrv No,
(WUM
0250f.75S7
(1UU1)
Ornl Toxlcltv, Toxic tin:
LU50- '"I'./M; Ac-iiti-
L)0
S)ihl-2
,:;inl K.K in.;
Ciiriv.it i-
DO
Toxlcoliv.v TLV
?0£. concon may ciiuu*
dyiipnca & tio;ula«:lm
Jn liams; 4(12; n.iy
^^
rtrr(n»<...^^l
^F
900.00? iipm in air,
lethal tor rats
Acrolcin
ClIjCHCHO
15 Acrvlanide
0001070:3
(VH1U1)
000079061
(ZV1U1)
46 orl-rat
7 orl-rbt
170 orl-rat
170 orl-nus
LDLo: 126
orl-rbt
LOLo: 252 ng,
orl-gpg
L)irr-3
alr-1
S)ing-3
ihl-3
skn
abs-2
L)irr-3
alr-3
ing-3
ihl-3
S)ir.g-3
ihl-2
ska rbs-2
L)ivr-3
alr-1
S)U
L)lri.-2
alr-2
S)ihl-2
skn
abs-2
TCI-o: 1 ppm, USOS air: TOA 0.1
TFX-1XS, ihl- man ppn or 0.25 rag/o3
LCLo: 153 ppci/ .
10H, ilil-hnn
Lachryzatorv irr
to eyes & res-
piratory tract
Absorbs through
unbroken skn;
CN'S paralysis
in anioals
LDLo: 1000 mg/kg,
skn-rbt
USOS air:
mg/n^ (skn)
0.3
16 Acrylic acid
CjHjCCOH
000079107
(QV1U1)
340 orl-rat
60 orl-ous
L)irr-3 L)U
ing-3 S)U
ihl-3
S)U
LCLo: 6000 ppa/5H,
ihl-rat
LDLo: 128 og/kg.
ipr-mus
LD50: 280 ng/kg,
skn-rbe
17 Acrylonitrile
DP CHjCXCS
000107131
(NC1U1)
93 orl-rat
93 orl-rbt
. TDLoilS ppn/20M,
TFX:rUL, ihl-nan
Hip.h toxlctty:
little evidence
oC cccunulation
LC50: 576 ppn/4H,
LCLo: 500 ppm/411,
ihl-rat
J.C100: 764 ppn/lH,
ihl-mua
LCLo: 120 «ie/V.B/4H,
Ihl-do;
LCLo: 600 ppm/411,
ihl-cat
USOS air: TWA
20 ppm (skn)
or 43 cg/=i3
18 AdIpIc acid
COO1I(CH2)ACOOH
00012'.0'.9
(QV4VQ)
1900 orl-mus
O.ULo:3600 orl-
rat)
Ixiw toxictty,
based on limited
animal studies
-------
A-i.
Seucct*:! of I'ruvi-ss
Holhlne-os -«o 107A
Hydrocarbon 167B
feedstock, costly
methane.
Propylone- 233
oxygen.
Cuprous oxide cat
Acetaldchyde,
formaldehyde.
LI phosphate on Al-0-
Acrylonitrile, 259A
cone sulfuric 2593
acid, ammonia or
sodiua hydroxide
Acrylonitrile, 259C
water
Ethylene oxide, 148
hydrogen cyanide,
sulfuric acid
.
Propylcne-air 248
Process
Tyro lysis
(BASK process)
Pyrolysis
(Huels electric
dlcharjc pro-
cess)
Oxidation
Cross-aldehyde
condensation
Hydration
Direct hydration
over catalysts
Addition, Hydro-
lysis (Addition
4 Oxidation)
(Process consi-
Oxidation
Assocliite.l Wast,-
'W:ist«-.i Tivaliwiit
Air; hydrocarbon Electrostatic
from feedstocks, car- milts, water
incomplete combustion ine, cuitc beds &
bap filters
Emission factors :
SOi - 4.2, hydro-
carbons - 2.0
Air; propylcne(142 '}/ Propylcne ahsor-
ton), propane (7 if/ bcr ofl-gas
ton), CO (147 J/ton)
F i i f
sane as air
Water: acrylic acid.
acryloni trile , amcio-
nia, sodium hydrox-
ide, sulfates, acry-
laoide
Reported to be pollu- Reported to be
tion free pollution free
V.'ater: ethvlene oxide,
ethylene cyanohydrin,
sulfuric acid, acrylic
acid, annoniun bisulfate
high, - listed in Table
A-4
Air; acetone (,35kg/ Solv recovery
Kg), acrolein (1.S5 colunn
Total
Pro.lm-i Ion
230.2 (507)-
non-che.mival
use)
26.0
(61.7)-
1974
18.2 .
(40)-
1973
See above.
59.7
(131.6)-
1973
431
(948.)-
1974
(includes
esters)
See above
U::es References
Syn: 333 vinyl chloride 4 1)6-531
vlnylUlene chloride: 261 4)11
acrylatos" 17« vtuyl ace 3)355
tate; 20.'. acelnl Jcliydc , nco- 7)1-203
prene, ncrylonitrilc, tri- 13)28
chlorocthyleue, cycloocta-
carhoa black nisc: also
veli! ins & cutting cvtals
" 1)6-537
12)
Mcthlonine (chicken 4 dog 1)6-7-85
food fortifiers). Int for 2)43
syn glycerol, polyurethane, 3)360
polyester resins, pharn; 5)559
herbicides; tear gas 10)
12)
Syn for dyes, etc; polymers 1)6-663
or copolysers as plastics, 1)5-855
ac*hesives, paper & textile 3)360
sizes, soil conditioning agn;
f locculants; sewage & waste
treatnent; ore processing;
permanent press fabric
" 1)5-866
Syn: 20X ethyl and irethyl 1)6-469
acrylates, 6.SX r.-butyl 4 2)43
isobutyl acrylates, 6.8Z 6)604
2-ethyl hexyl 4 other 7)1-311
acrylates; plastics; paper; 12)
paints 4 coating's; floe- 13)28
culants
1)6-825
kg/Mg), ethyl acetate
(38.7kg/;ig), propylcne
(6.25kg/Mg), CO (502
258
Ethylene
cyanohydrin
Acetylene,
HCS
Water: acrylic acid
(10kg/Mg), polyners
(20.6ks/Mg), hydroqui-
none (10.65kg/'!g),
acetic acid (35.7kg/Xg)
& ethyl acetate
(27.25kg/Mg)
(See Acetonltrile Fntssion factors: very
above) high - listed in Table
A-4
614.8 Mfr: 55Z acrylic 4 mod- 1)6-859
(1354.2)- acrylic fibers 4 high- 2)45
1973; strength whiskers; 20/: 3)361
642 ABS 4 SAN copolyrers; 5Z 5)559
(1412)- nltrile rbr; cyanoethyla- 6)606A
1974 tion of cotton; syn soil 11)36
552 blocks (acrylonUrile 12)
(1215)- polymerized in wood pulp);
1975 org syn; grain funigant
Cyclohexane,
air, catalyst,
nitric acid
41 Oxidation Air; nitrous oxides &
nitrogen dioxides,
particulars
Wntcr; metallic cata-
lyst residues, by-
product org acids
T'nlsfllon fartnrr.: N0? -
12.0, partlcuj'at^s - 1.8
711 Mfr: 90Z nylon fibers & 1)6-151
(1567)- resins, 4X urcthane foama; 2)47
1973 5Z esters for use as plas- 3)3r,2
7e4 tlclzers & lubricants; 0.5% 6)6068
(1630)- ingred of foods, as acldu- 7)1-414
1974 lont; Inaccj adhcslvcs; 11)36
568 tanning; tcxtll<: printing; 12)
(1470)- fauna inhib; cunctnss; 13):'8
1975 detergents; ulaatomcru
-------
A-V
TABU: A-K (
Cnr.:;K'umt Cliom. Atistr*
lltm liana im.l Ki-r.istry Nu. Oral Ti.'xltjllv, IVxIC l!;ir
No. Ki'rail.i (WI.IO '-"SO1 '"''"'K A.-Hl,'
19 Allyl alcohol 000107)56 96 orl-nnis L)irr-3
CII.CHCII.,011 (Q2U1) mio: (.9 thl-l
re II 0)" r,rl-r,.r S)lnS-2
36 Lni.p: 43 lhl-2
orl-dep. sliUn'
CliriMilc
L)lrr-3
ihl-3
Sjlns-:1
lhl-2
skn
abs-2
Toxlcolofiv
TCI.o:25 pp:s.
Trx:IIU'., Ihl-hicn
Irr to skn, eyes.
rosplr.itory
tract ; kldiify 4
livor d.imaf.e .
TLV
USOS air: TVA
2 pp:n (skn)
or 5 ns/n3
Gardner
orl-rht
20 Allyl chloride
(Proptae, 3-Chloro-)
21 o-Aoinobenzoic acid
DP (Beczoic acid, a-Ainino-)
000107051 LDLo:64 orl-rat L)irr-3 L)irr-2 Eye & mucous raeo. USOS air: TVA
(C2U1) ing-3 ing-2 irr. Local vase. 1 ppm or 3 ng/n3
ihl-3 ihl-2 construction & nun-
S)ing-2 S)ing-2 bness; rapid body
ihl-2 ihl-2 dist;
»kn skn LCLo: 290 ppa/8H,
abs-2 abs-2 ihl-rat
LD50: 7150 eg/kg.
Ivn-dog
000099058 " " " LDLo: 500 ng/kg,
(ZR CVQ) ipr-nus *
TDLo: 8400 =g
84 DI
TFX:KIO, orl-
22 p-Aaino-benzoic acid
D?
23 Amiaoethylethanol-
aodne
QEthanol, 2-(1.2-anino-
ethyl)atnino)-J
000150130
(ZR DVQ)
000111411
(Z2M2Q)
24 Aayl acetates
(n-Pentylacetaco)
CH3COO(C»2)4CH.,
600 orl-rat
2850 orl-c.us
1830 orl-rbt
LDLo: 1000
orl-dog
3000 orl-rat
000628637
C50V1)
25C Aayl alcohols (8 isomers)
(n-Pentyl alcoliol) 000071410
CI1CHCI!2CH2CH01I (Q5)
26 Isnarayl slr.ohnl 000123513
(Isobutyl c.irblnol) (Q2*)
(l-Butanol-3-ni!thyl)
1300 orl-rot
Large oral doses;
nausea, skn rash,
Eethcnoglobinenia
LD50: 2000 ng/kg,
ivn-rht
Unknown; possi-
bly lov toxicity
LD50: 1800 ng/kg,
skr.-jpg
7400 orl-rbt
3030 orl-ra:
200 orl-mus
. L)irr-l
ing-2
ihl-2
S)ing-2
ihl-2
L)irr-2
ihl-2
S)ihl-3
L)irr-l
S)U
L)lrr-2
S)ing-3
Hil-2
skn
abs-2
TCLo:188 ppt=/30M.
TFX:IRR, ihl-tem USOS air: TVA.
Low chronic toxi- 100 ppm or
city; irr to one 525 =ig/n3
mem; narcotic
LCLo: 5200 ppn,
Ihl-rat
LOLo: 1500 ng/,g,
ipr-rat
Possible eye &
upper respira-
tory tract irr
LDLo: 490 ng/kg.
ipr-rac
USOS air: TWA
100 ppn or 360
mg/a-1
27 An/la^iincs
000110587
470 orl-rat
L)irr-3 L)U
ihl-3 S)U
S)U
1120 skn-rbt
Strong Irr
LCI.o: 2000 ppm/4l(,
ihl-rne
-------
Sources of Process A.isoctatetl
Coxp.".im! No. 1'i-iVi'S.-: U':istfs
Acrolclll - 23-'iA Hydrogen W.it.-r: (lle.lit ends
2~butunol transfer column), aerolein (25
tf/lon), nvlhyl/ethyl
ketone (.'5- /toil), J-
butanol
Wator: (lu-jvv ends
column), J-hutanol
(15-;/tou), allyl al-
cohol (10v/ion), poly-
mer (I07,?/ton) i
alumlnuat hydroxide
Waste Total
Ti'.'.iti-i-nt I'lvJiict it'll Uses
I'l-tl-i^ion f.-u-tory: -- Esters for use in rosins
hydrocarbons - & plust Icliers ; int for
3.0 pliarin & other org cliem;
ctfr of glycerol & acrololn;
military poison gas;
herbicide
Rofereueen
1)6-787
2)55
3)367
5)559
12)
Propylene glycol 270
catalyst
Propylene oxide
272
Dehydration
Isotncrl ration
Allyl chloride, 301
dilute sodiun hydride
& dlothyl ether
Air & U'.itor; propy-
Icno glycol, allyl
alcohol
Vn_tcr: allyl alcohol
(13kg/:i.c)l n-propyl
alcoliol, xylcne tars
(25»5kg'!?n), tcrphc-
nyls (12.5kg/Vg),
lichiuo phospliate
Substitutioa Water: allyl chloride,
(Saponification) allyl alcohol, diallyl
ether
Propylene-chlorine
298
Chlorination
Air: propylene (27"/
con), ethyl chloride
27-J/ton)
Warer: sodium hydroxide
. Emission factors:
same aa air
Absorber
395.4 Prep of allyl alcohol &
(869.9)- other deriv; thernosett-
1970 ing resins for varnishes,
plastics, adhesive?; syn
of pharm; glycerol &
insec
1)6-897
1)6-901
1)6-987
1)6-979
2)970
3)363
5)559
12)
£, p-nitrobenzoic
d, catalyst,
rogen
313
Reduction
Water: benzaldehyde,
cyclic alkyl nitrates
Dyes; drugs; perfumes;
phana; dye int
1)6-1021
2)132
3)380
4)53
Ethylenec'lamine,
echylene chlorohydrin
134
Alkylatioa
Water: HC1, NaCl,
NaOH> org possibly
in separation
vaseewater
Scrubber
6.1 Textile finishing com- 1)6-429
(13.5)- pounds (antifuaing agn, 2)512
1974 dyescuffs, cationic 3)381
eurfacants; resins, rbr 12)
products, insec & certain
ciedicinals
A=yl alcchols,
acetic acid
50,
229
Esterification
Air & Vfater: acetic
acid, amyl alcohol,
amyl acetate, sul-
furic acid
Emission factors:
hydrocarbons - 2.0
5.4
Solv for lacq & paints; 1)6-181
extraction of penicillin; 1)5-763
photo film; leather 2)24 .
polishes; nail polish; 3)398
warning odor; flavoring 5)559
agn; printing & finishing 6)603
fabrics; solv for phosphors 12)
in fluorescent lamps
Mixed butylenes: 49
1-butene, 2-bucene,
methylpropene; CO,
H,
Mixed amyl chlorides, 227
sodium hydroxide
*Aayl chloride arjrtonia 226
Oxo process
Substitution
(Hydrolysis)
AnlnatIon
(Arctnonolysls)
Air; CO, butylcnes
& alcohols, dtmers
Water; NaOH, K.iCl
amyl elcohola, atnyl
chlorides, pentylcncs
& orayl cthor
A1r: nmyl chlorido,
on?nonla, nmyl amines
Water; nnrmmlum
chloride, heavy ory,
Incineration,
off gases to
flare
Solv; mtrl for pharm prep;
org syn; lubricants;
plasticizcrs; additives
for oils & paints; floca-.
tion agn; medicine
Chen ine; dyestuffs, rbr
chcm; Insec; syn deter-
gents, flotation a^n;
corrosion Inhlb; solv;
gasoline a'ldltlvu; pdarm
1)6-177
2)843
3)398
1)6-759.
2)843
3)399
5)561
1)6-737
-------
A-'J
TAIIU: A-l. (Conciuucvl)
I (cm
No.
:8 Any! cli
Ccvajiound
NA-U; and
Kcvnntlu
lor '.do
LO. 1-Cliloro-)
Cli-'m. Ali.itr.
RvKistry No. Or:il Tuslcliy, Ins to l-niiivil Rjrliu; ^^
(WIN) '-":.0- "t'-'kS Ai'uti- Cl.iM-.iU- Toxli.-Dlo>;v TLV ' r.ro( r,.,,...^M
^P
0005'.3599 Unknown
(G5)
Atnyl oereeptrtna
(l-Pontnnctlili>l)
000110667
(S»5)
L)lrr-l
nlr-l
lng-1
ihl-1
S)U
L)Dlr-l
LCLo: 2000 pp3>/411.
30
DP
Aniline
C6H5KH2
000062533 500 orl-dog L)alr-2 L)alr-2 Forms mothcmoslo- USOS air:
(ZR) *^0 orl-rat S)lng-3 S)ina-3 bin, anoxe=iia, de- WA 5 ppa
LULo: 350 orl- i!>l-3 ihl-3 prcssion of CX5, (skn) or
hum skn skn contact dcnrucitis; 19 nj/m^ (skn)
LULo: 1750 abs-3 «bs-3 possible blood pres-
orl-cat sure lowering &
cardiac arryihaia
31 Aniline hydrochlorlde OOOK2041
-------
Sources of Process
Compound No.
Pcntntic, isopcn- 225
tone, chlorine
Any Ich lor ide, sodLum 223
or pot jiSsiu::i hydro*
sulfide, alcohol solv
A»»UH- In toil U'ii.'ile
VYtu'uss U'.'IHI i':: Tivni ::ucr.Kciiu -
0.3, amnonla - 0.3
207.S Syn: tOS isoeyanncos ODI 1)6-67
(457.6)- i PAPPI), 35" rbr aecelcra- 2)105
1973; tors & antiosidap.ta. 61 dyes 3)103
250 S inc. 6Z hyjroquinone, 4)35
(551)- 42 ph.irnj explosives; 5)559
1974 potroloun rclinlny; diphe- 6)603
167 aylamlne; phenallcs; 11)35
(412)- herbicides; fungicides; 12)
1975 textiles, paper £i ciotallur-
gical ind; catalysts;
stabilizers
Nitrobenzene 24
hydrogen
Phenol, atunonia 2S3
catalyst
Aniline, hydrogen 27
chloride
^Tailine, concen 285A
hydrochloric acid 285B
°~> p-nitroanisole, 294
hydrochloric acid,
Reduction
Ammonolysis
Salt Formation
(Hydrochlorina-
tion)
Salt Formation
(Chlorination)
Reduction
Wa_ter: aniline heavy
residues
Air: Hj, N'j , ammonia,
phenol, aniline
Air: HC1, ether (solv)
See above
Water: aniline. HCl
Water: iron or tin
salts & org
Heavies inciner-
ated waste dis-
posal problems
considered ciini-
mal -by thia pro-
cess
«
--
See above
See above
tta or iron filings
Sodiuu phenate
(sodium phenoxide)
aethyl chloride
Phenol
sodium hydroxide
dimethyl sulface
287A
237B
Methylatlon
(Substitution)
Methylation
(Substitution)
Water: Nad, NaOH,
phenol, sodium phe-
naCe, methyl chlor-
ide, anisole
Air; nethyl chloride
Hater; sodium sulfate,
sodiua phenatc, sodium
hydroxide, phenol, ani-
sole, dimethyl sulfate
Ftichalimide, sodium 209
hydroxide, chlorine
or bromine, hydro-
chloric acid
Hydrolysis & Water: Nad or KaBr,
Hofnann Reaction phthalimide, anthra-
nilic acid
Air: chlorine or
bromine
Pnthalic anhydride,
benzene, AlClj,
lulfurlc ncid,
sodium carbonate,
sodium hydroxide
207A
207B
Condensation
Water: Nad, NaOH,
aluminum salts, sul-
furic ncid, benzene,
phthallc anhydride,
o-bcnzoylbcnr.oic acid
0.9
(2.0)
1973
1)6-105
7)2-419
1)6-929
Dyes; Ir.t; dyeing & print- 1)6-111
lag; aniline black 2)162
.3)408
1)6-935
1)6-937
3)409
IDC for azo dyes & for
gualacol; azo dyestuffs
Dyes; drugs; perfumes
phara
Int for dyes; & org; org
inhlb; bird repellent for
seeds
1)6-967
2)113
3)410
Solv; perfumery; vermicide; 1)6-941
Inc 2)113
3)410
1)6-943
1)6-709
2)115
3)411
1)6-599
1)6-705
2)116
3)411 '
8)31
-------
A-11
T.MIU: A-1. nlliiiu-J)
I ton
.to.
Cocipouml
N.tao ami
Forr.iuln
Cticm. ANstr.
RiiKlsrrv [In.
Oral l\>xl>;lcy,
'
Toxic H.iznri 1 ll.it iny.
Aciu.- g.ror.lc
Tl.V
37 Bcnzaldchyje
OP C6115CHO
000100527
(VHR)
1300 orl-rat
1000 oi-l-tps
L)alr-l L).ilr-l
S)ing-2 S)li<£-l
ekn
abs-1
CSS depression in
siiuill Joscs; con-
vulsions in lur&er
dosus; contact
dermatitis
LDLo: 5PUO irg/kg,
scu-rat
33 Bonzanide
C6HjCOSH2
000055210
(ZVR)
1150 orl-nus
39 Benzene
000071432
5700 orl-rat
(Ref 4)128)
3800 orl-rat
(Rcf 2)163)
4700 orl-rius
LDlo: 2000
orl-dog
L)irr-2
ing-1
ihl-1
S)ing-2
ihl-2
skn
abs-2
L)0
S)ir.;-3
ihl-3
skn
abs-3
40G Beczenedisulfonic acid
40 1,2-C6K4(S03H), . 2 Hf (WSQR BQSW)
41 Benunesulionic acid
HP C,H.SO,H
o y J
42 Ber.ztl
^"lO^J
(WSQR BQSW)
0000=3113 890 orl-rat
(WSQR) 75 orl-bdw
L)lrr-3
ing- 3
ihl-2
S)U
L)irr-3
ing-3
ihl-3
S)U
L)irr-2
S)U
L)U
S)U
000134816
(R.WF.)
2710 orl-rat
LCLo: 20000 USOS air:
ppm/SM.tlil-hnn 1VA 10 ?pa
TCLo: 210 ppn or 30 cj/m^
IFX-BLD, iia-hEn fSOS air cay be
Eryth=la, bui-nlng, lowered to: TVA
edena i blistering;1 ppn ty Oct. 1976
narcotic to CN3; (Chen V* 9/1/76,
anesthetic; acute 10)
chronic effects
LC50: 10.000 ppm/7H,
ihl-rat
TDLo:1232 ng/kg/
52W
TFX:CAR,skn-nus
Unknown
43 Benzilic acid
000075937
(QXRi?,&VQ)
Unknown
44
Benzole acid
DP C,H,CO..H
op t.
46 Benzonlcrlle
000119539
(QVRiVR *DXLV)
000100470
(NCR)
I.DLo:720 orl-rat
alr-1 S)U
ing-1
S)U
LD50: 1200 mg/kg,
okn-rat
LCLo: 950 ppn/8H,ihl-rat
LDLo: 180 t3g/kg,scu-mu3
47 Benzophenone
C6KSCOC4«,
(C13"l00)
000119619
(KVR)
Unknown
48
Bcn^oquincne
(Also Quir.onc)
0001M514 130 orl-rat L)irr-3 L)lrr-2 Irr to okn (, USOS air: TDLo:2000
(L6V UVJ) S)ln((-3 S)lnf.-3 eyes , T-'A 0.1 ppm
lhl-3 iiil-3 LCLo: 320 ma/o3, or 0.4 ag/m^ TFC::^0,
LD50:8500
LT>r.O: 25
tvn-rac
-------
Sources of
Compound
Toluene, air,
catalyst
Process
No. Prtvosn
343 Oxidation
A:*fioel.itod Waste
WilfcUu Treiltmrnl
Air; CO, C0.; Scrubber
Wntcr: beii'/.ote ucid.
malclc anliydvlde,
anthraqulnone
Total
Protluc; Ion Uses
Org syn (especially of dyes
& dye Int); solv for oils.
resins, some cellulose
ehtcrs, cellulose acutnte
References
l)b-1091
2)154
3)439
7)3-363
Benzoyl chloride
omaanla
322
Amoonolyjls
& nitrate flavoring cew
pountts; syn pcrfutntis; =if r
of cinnjuic aciJ, benzole
acid; ptmrni & ?onps; p!ioco
cheat; b.ikinj; chern; tnsec;
cedlcino; herbicides; corro-
sion inhib
Org sya
1)5-1041
2)155
Toluene, hydrogen,
. Co aroraatics, alkvl-
. o
337
benzenes
Benzene sulfonic
acid; 657. oleum;
a-benzenedlsulfocJLc
acid; catalyse
Benzene; sulfuric
acid or oleua or
sulfur trioxlde
Benzoin; CuSO,,
dine; acectc
; .^03
Benzll, fiodlum
hydroxide, hydro-
chloric acid
19
18
345
346
Transalkylatlon By product formation:
29kg/>
-------
A-n
TAKIJJ A-l. (<\Mil Inm.l)
Compound
Item Nnr^e find
Ne>. Forrauln
49 BiMizotrLchloridc
DP (Toluene, a, a, a-
trlchloro-)
C.H.CCl,
6 S 3
50 Bcnzoyl chloride
OP C.H.COC1
O J
(CjHjCIO)
51 Benzyl alcohol
C.H.CllOH
652
(Cj^g0)
52 Benzylataine
C.H.CH.NH,
6522
(CjHgN)
53 Benzyl benzoate
(Benzoic acid, benzyl
eater)
C,HeCOOCH,C,H.
65 265
(C..H..OT)
x 14 12 2'
54 Benzyl chloride
DP (Toluene, or-Chloro)
C,H.CH,C1
65 2
. (c,H7ci)
55 Benzyl dlchlorlde
[Benzene, (Dichloroiethyl)!
C.H.CKCl,
652
(C7H&C12)
56 Biphenyl
C H C H
6565
57 Bisphenol A
(Phenol, 4, 4'-lsopro-
pylidenedi-)
(C..H..O,)
15 16 2 ,
53 Bromobenzene
(Benzene, bromo-)
59 C Bromonapthalcne
59 (l-Bromonapchalcne)
,C10H7Br
Chcm. Ahrttr.
RcgtsTcy No.
00009S07/
(CXCCK)
0000*3834
(GVR)
0001C0516
(Q1R)
0001C0469
(Z1R)
000120514
(RV01X)
0001K434
(G1R)
0000=3873
(CYC*)
000032524
(RR)
000030057
(OR DXR DQ)
000103861
(ER)
02497514
' (L65J BE)
Or.ll Tovli-Ky,
600 orl-r.ic
3100 orl-raL
(Ret 4)
1230 orl-rat.
(Re£2)202)
15SO crl-uus
1940 orl-rbt
100 orl-bj«
/ 1700 orl-rat
1400 orl-cus
2240 ocl-cat
1800 orl-rbt
1000 orl-gpg
1231 orl-rat
1624 orl-cus
.
3249 orl-rat
467 orl-cvjs
3280 orl-rat
2400 orl-rbt
..
..
Toxic Jt:K'ii
Acutf
L)irv-3
ing--
lhl-3
S)ln^-2
ihl-2
L)irr-2
ing--'
. lhl-2
S)U
L)irr-l
alr-1
ing-1
ihl-1
S)inj;-:
ihl-2
skn
abs-2
L)irr-3
ing- 3
lhl-3
S)U
L)alr-l
ing-1
ihl-1
S)U
L)irr-3
ing-3
ihl-3
S)ing-3
ihl-3
akn
abs-3
L)U
S)ing-2
ihl-2
L)U
S)U
L)irr-2
S)ing-l
ihl-1
ml 1C:- rim;
Cli !'.>:. u-
L)II
S)U
I.)lrr-l
S)U
L)lrr-l
nlr-1
S)U
L)irr-2
ihl-2
S)U
L)alr-l
S)U
L)U
S)U
1)1'
S)i:ig-2
ihl-2
L)U
S)U
i)c
S)U
ToxK-olo.'.v TLV
Irr to skn & muc
nera
lDLo:125 ppm/411,
ihl-rat
--
Irr to skn &
ciuc mem, vertigo
nausea & diarrhea
LCSO: 1000 ppa/SIl,
ihl-rat
....
TCLo: 16 ppm, USOS air: TWA
TFX:liN5, ihl-hmn '1 ppa or 5 ng/a3
LD50: 1000 mg/kg,
scu-rat
CHS depressant;
strong irr &
lachrymator .
LCSO: 200 05 /a ,
ihl-c'js
2500 =g/kg,skn-rbt USOS air:
TDLo:4400 mg/a TWA 0.2 pra
TFX:I3K, ihl-han. or 1 ag/mi
Experioentally caused
paralysis & convulsions
in anitaals
LD50: 150 mg/ USOS air:
kg, ipr-mus TWA 0.5 ppm
or 2.8 ng/a-5
9
..
.. .
..
TDLo: 50 ag/kg
scu-rat, ^^
TFX:NEO ^A
TDLo: 2100 S^J
kg/51WI,
TFX:NEO, scu-rac
(KaphthaUne, bromo-}
-------
Process
No.
ProcgsH
W.-isie
T«Jt.il
Toluene, chloriiu1, 317 Chlorliuitlon l.'nti-r: chloride M.ilt:;
PC13 ov PClj
Syn dyes; orj; flyu; inscc;
degronslng sotv; dK'loc-
trlc fluid; lubricating
oil additive; coolant
3)444
4)135
7)5-265
Bonzotrichloride
benzole acid
Benzyl chloride,
scJium carbonate
320
313
Exchange
(Hydratlon)
Substitution
(Hydrolysis)
Benzyl chloride
acmonia
319
Agination
KnJ.sj_ton fa.-1ors: l!i:i
5.0, SOi - 3.0, "bi-iir-olc
acid - 0.1
I0/;tor: N.iCl, sodium
carbonate
M.'dlcinc; int fac pro- 1)6-1035
duction of bcnzoyl groups; 2)201
int tor ochor org 3)445
12)
5.9 Perfumes & flavors; plicto 1)6-1031
(12.9)- dcvolopcr for color cuvic 2)202
1973 films; dyeing nylon fila- 3)4*"
6.3 mont, textiles & s!\eet 4)133
(13.9)- plastics; solv for dye- 12'
1974 stuffs, cellulose esters,
casein, vaxes, etc; heat-
scaling polyethylene
films; int for beniyl esters
& ethers; local anesthetic;
cosmetics, ointnents, emul-
sions; ballpoint pen inks &
stencil inks
Chen Inc for dyes, phara 4 1)5-1033
polymers 3)445
Beazaldehyde,
acdium hyJrcxide
316
317
Esterification
(See benzotri-
chlociee above)
Water: benzyl benzoate,
bcnzaldehyde
Er.Isslon factors:
toluene - 2.0, HC1 -
2.0, benzyl chloride -
1.0, HC1 - 2.0
0.64
(1.42)-
1974
36.5
(30.4)-
1972
Fixative & solv for musk
in perfumes & flavors;
medicine (external); plaa-
ticlzer; miticide; insect
repellent; cosmetics
Syn: 65J butyl benzyl phth-
alate, 14* benzyl alcohol,
12Z quaternary aoiconius)
conpounds, dye inc; syn
tannins; perfumery: phara;
&ifr of photo developer;
gasoline gun inhib;
penicillin precursors
1)6-1027
2)133
3)446
4)133
7)3-432
12)
1)6-1029
2)1139
3)447
5)560
6)611
8)308
12)
317
(See benzyl chloride)
Dyes
1)5-1029
2)166
3)439
Eronobenzene,
benzene, sodium or
copper
47
Ullmann Reaction Air: benzene
(Substitution)
Fhenol, acetone, HC1 239
Alkylation
Valar: phenol (14.2v/
ton) COD, TOD given
_Emtssion factors:
acttone - 3.0, phenol
3.0, 1IC1 - 1.0
2.3
(5)-
1971
(77.9)-
1973
145.1
(319.7)-
1973
171.1
(376.8)-
1974
Org syn; heat transfer agn; 1)6-167
fungicides; dyeing assis- 2)218
tant for polyester 3)595
5)560
Hfg: 492 epoxy resins, 381
polycarbonate resins, phe-
noxy ! polysulfone resins;
brake fluids; fungicide for
textiles S cable coverings
1)6-803
2)864
3)458
5)5fiO
6)612
7)1-912
12)
13)29
Benzene,bromine
catalyst
46
Bromination
Air! benzene
Solv; motor fuels; top- 1)6-165
cylinder compounds; crys- 3)474
talllzing solv; org syn
Kaphtholene, bromine, 199
carbon tetrachloridc*
catalyst
Brontnation
Air; hydrogen bromide
Org syn; microscopy;
refractomctry
1)6-575
-------
Co'.u pound
Item N.i-.:i«: nnd
Ko, Koriv.ula
60 Bulntllont!
CHjCltCCHj
(C4l!j)
A-l'i
TAI1IJ-: A-l. (i:,mUuui-il)
ChiTO. Abiilr.
R.'glstry Ho. Or.il Tuxlxtlv, T.'xle i'iiznnl K.itin.-
("L!O Ll'iO' "'B/k|; Ai-iitc Cln.-.iK- ToxU-oloi-y TLV Carcii-.o^o-
000106990 -- L)irr-2 L)ivr-l LCLo: 250.000 USDS air: TWA
(1U2U1) inix-2 S)V ppm/-5H. ihl- 1000 ppm
ihl-- . limn
S)ihl-2 Irr to eyes &
nuc aem; (hi of
high coiicen can
cause unconscious-
ness & death
61 Butnne
CK3CH2CH2CH,J
000106978
(4H)
L}0
LC50: 658 mg/ra . Air: TWA 500
ihl-rat ppm
62 C Butencs
(Butylenes)
Asphyxiant
62
63
64
65
66
67
68
1-Butene
2-Butene
Isobutyler.e
(Propone -2 -nechyl)
n-Butyl acetate
(Acetic acid, n-
Butyl ester)
CK-COOC. H-
ft* M ft
(C6H12°2
sec-Butyl acetate
(Acetic acid, sec-Butyl
ester)
CH.COOC. Hn
3 49
(f* H 0 )
» tio t'
6 12 2
tert-Butyl acetate
(Acetic acid, tcrt-Butyl
ester)
CH3C020(CHJ).J
(C H O }
v 7 12 2;
n-Bucyl acrylate (2-
Fropcnotc acid. Butyl
ester)
(COH.-0.. )
000105989
(3U1)
000107017
000115117
(1YIII)
000123S64
(40VI)
000105464
(2YCV1)
000540885
(1XCV1)
000141322
(4QV1U1)
LDLo: 3200 L)lrr-l
orl-rbt alr-1
LDLo: 4700 ing-1
orl-gpg ihl-1
S)ing-2
ihl-2
skn
abs-2
L)irr-l
alr-1
lng-2
ihl-0
S)ing-2
ihl-2
skn
abs-1
L)irr-l
alr-1
lng-2
lhl-0
S)ing-2
ihl-2
skn
obs-1
3730 orl-rac L)irr-2
lng-2
S) lng-2
-
L)alr-l
irr-1
S)ihl-l
ing-1
skn
abs-1
L)alr-l
S)lng-l
ihl-1
skn
abs-1
L)alr-l
S)ing-l
ihl-1
skn
abs-1
L)U
S)U
n
"
it
TCLo: 200 ppji,
TFX:1RR, ihl-
hmn
Irr to eyes &
respiratory
tract; evidence
of chronic sys-
temic toxicity
is inconclusive
LD50: 1230 ng/kg,
Ipr-aus
LDLo: 1500 ng/kg.
Ipr-rat
.-
__
LDLo: 1000 ppra/411,
(111 -rat
LD50: 2000 mg/kg.
skn-rbt
--
USDS air: TWA
150 poa or 710
og/ap
USDS air: TWA
200 pya or 950
Eg/m3
USOS air: TWA
200 ppn or
950 og/p3
.
lao-Butyl (icrylatc
000106638
(IYIOVII'1)
LCLo: 2000 ppm,
ihl-rat
-------
A- I li
Sources of Process
^^^itenca. hydro^n. 55
furfural catalysts
n-butcnes, olr, H.,, 223
furfural or ace-
ton! trlle
PrcH-.-ss
Dehydration
Dehydration
(Oxld.ltive
dehydrocenat ion)
Associated Waate
100 flat of waste per ton
of [.reduce, COO 4 1'UC
given
Water: oils & tars
Air: furfural
See above
Total
Product Ion
1674
(3682)-
1974
1202
(2645)-
1975
See above
Uses
47'£ styreiie-butad tciw
rubber, 177. polybut.Ulenc ;
8Z neoprenc rubber; ST.
syn flvllponi trlle.
(Z ASS resins; 3%
nitrite rubber; latex
paints; misc
..
1)6-191
2)238
3)479
6)612
7)
13)30
1)6-751
R-butune, H>, fur-
fural or acetonitrile
224
Dehydro^enation See abov
See above
1)6-753
n-butane,
furfural or
eceConicrlle solvent
210 Separation
221 Dehydrocenation VaEcrt furfural or
(Dehydration) accConitrile, vari-
ous C^ hydrocarbons
Air: light hydro-
carbons
Chen nfr; liquified gas; 1)6-717
heattnj:; motor fuels; 2)239
refrigerants; solv; flood- 3)480
ing agn; blo-'ir.g agn 7)3-815
10,074 S1Z gasoline; nzg: 6.01
(22,190)- butadiene, 1.9X butyl
1967 elastocers, l.SZ sec-
buyl alcohol, l.SZ roly-
butcnes, 0.5. specialty
chemicals(C(, & 05 alcohols,
aldehydes & deriv.) 0.3Z
diisobutylene, 0.3X poly-
isobutylenes, 0.25*
kepcenes, 0.1Z misc.
494
(1087)-
1974
Syn: > 75Z butadiene, 23Z 13)30
sec-butyl alcohol, 2'i Rise
obuCane
Kfr: 72" butyl elas:o=ers, 1)6-745
18Z specialt7 chemicals, 13)40
10Z polyisob-jtylenes
o*bucanol, acetic
acid1.
88
Esterlfication
Uater: n-butyl acetate,
n-butanol, acetic acid,
sulfurlc acid
Air: n-butylacetate,
n-butanol
Enisslon factors:
n-butyl acetate - 1.0,
n-butanol - 1.0
36.8 60S solv in production of 1)6-237
(81.0)- lacq, lacq enasels, pyro- 2)14
1973 xylin solutions; leather 3)483
dressings; perfuces, 3)560
flavoring extracts; solv 6)613
for natural gums & syn 12)
resins; dehydration a£n 13)30
aec-butyl alcohol,
acetic acid, culfuric
acid
53
Esterification
Water: 17, ester, 37.
alcohol
Air: ester & alcohol
vapors
<24.9 Solv for nitrocellulose; \)6-187
(<54.9)- lacq; thinners; nail ena- 2)14
1967 mels; celluloid products; 3)483
artificial leather; leather 5)560
finishes; plastic wood;
vashable wallpaper
tert-Uutyl alcohol or 67
Isobucylene, glacial
acetic acid
Esterification
Water: acid, alco-
hol, acetate
Possible antiknock agn In
gasoline
1)6-219
2)14
3)483
5)560
Acrylic acid, n-
butanol, benzene
149
. Estorlficntion
ac id,
toobuumol, benzene
Wntor: acrylic acid,
eulfuric acid, n-
butanol, n-btitylacry-
late, benxnne
Katasion factors:
acrylic"ncl.d - 2.0,
butyl acecate - 2.0
Wqccr; acrylic acid,
>ulfuric uclH, iso-
bitCnii'iI, iKobutyl
acrylacc, bvrizone
58.1
(128.0)-
1973
Int in org syn; polyoerff 1)6-471
copotymers Cor emul-
sion & eolv coatings,
adhcslvcat (Mines,
binders, emu Is Iftcr3
2)972
3)484
9)20'.
12)
13)30
1)6-471
2)45
-------
Item
No,
70
DP
71
72
73
DP
74
75
76
77
78
OP
Compound
Nj:ne nnj
F.'rmuln
n-Butyl alcohol
CIU (CtL).CILOH
«V'10o)"
II
sec-Butyl alcohol
tert-But;l alcohol
(CIL).COi
n-Butyla^ine
sec-Butylatnir.e
tert-ButT-lamine
tert-But-lbenzoic acid
(Benzole acid, t-Butyl-)
l,3-Buty'.ene glycol
(1,3-Butsnedtol)
Ccrt-Butylphenol
(Phenol, tert-Bu:yl)
Clurm. Abstr.
KcRlxry Uo,
(UO
000071363
(04)
-
it
000078922
(QY2)
000075650
(QX)
000109739
(Z4)
013952846
(Zy2)
000075549
(ZX)
001320167
(QVS BX)
000107880
(QWQ)
000098544
(QR OX)
A-17
TAIIIJ-: A-l. (Ctmtir.m-J)
Ornl IX'sKUv. ToxJc M;i:-.;ir
-------
A-IH
Sources 01 Process
Coinpoaml No,
^k
^HKogend'!h>'le'
UC-feed:prop.ine, 212
air, forr-ildehyde
n-butyral4ehy-:umon: Production
Waiter: n-butani>l Heavy en s 235.4
cruluiuildchy.le JnclneraccJ (518.0)-
FmiBsUiii f Actors: 1973
CO - 152.0, hydro- 254
carbons - 5.0 (558)-
1974
155
U'il)-
1975
Water & Air: aldehyuVs. " "
alcohols, orpacids, ace-
tone, formaldehyde
Air; org vapors, Heavy cnJs
hydrogen burned: process
involves no
ciini!nal air
pollution
Water: butyl alcohol, 205.6
sodiun hydroxide, (453)-
sodiur.1 sulfate, sulfuric ' 1973
acid
Water: t-butyl alcohol. 508.5
sodium hydroxide, sodium (1120)-
sulfate, sulfuric acid 1973
Water: sodium chloride, 1.82
sodium hydroxide ; (4)-
Air 4 Water: bis 1973
t , . . ,\
ether
Emission factors:
butyraldehvde - 3.0,
KH3 - 1.0
Air: K>2, formaldehyde,
alcohols, acaonia
Emission factors:
butyraldehyce - 3.0,
NH3 - 1.0
Air: anznonia, hydrogen
Water: tert-butyl tou-
lene, tcrt-bucylbenzoic
acid
Air : ethanol, n-butanol,
2,4-dinethyl-l,3-dioxane
Water: dibutylene gly-
cols, acctaldehyde, ace-
taldol, 1,3-butylene-
glycol
Water: isoneric butyl
phenols, isobutylene
polyners
Uses
>o-
iivs; n£r: 14Z slycol others
12: plasttcizers, 12J! n-
butyl acetate, 10" amiro
resins, 7i n-bucyl acryl.itc.
10'. exports, 15- niac (i-'.g..
butyl amines and 2,4-D
esters).
ii
"
95" syn r.ethyl ethyl ketohej
solv; org syn; enamels &
lacq; hydraulic break fluid;
Ind cleaning £ paint rc-
coval; ore flotation; fruit
stuffs & vetting agn
Alcohol denaturant, chea
mfg; perfun^s; denaturant
Int for enulsifying agn;
pharm; insec;.rbr checi;
dyes; tanning agn; soa;s;
(I ^ r^ « «f
inhib; antioxidants for
gasoline; color photo;
curing agn for siloxanes
Int for rbr accelerators;
insec; fungicides; dye-
stuffs; phara
Resins & plastics; alkyd
resin modifier; corrosion
Inhib
Polyesters; polyurechar.es;
surface active agn; plas-
ticizers; hunecant; coup-
ling agn; solv; food
additive & flavoring
Chca int for syn resins,
plasticizcrs, surface-
active agn, per fuzes i
References
1)6-283
. 3)484
4)173
5)560
6)614
7)3-828
1-')
13)30
1)6-723
1)6-879
7)3-328
1)6-183
2)248
4)173
5)560
7)3-829
12)
13)30
1)6-211
2)248
3)485
5)560
7)3-829
1)6-885-
2)249
3)435
. \ C Cf\
7)2-124
12)
1)6-189
2)249
3)485
12)
1)6-217
. 2)249
3)485
1)6-215
2)184
3)487
7)436
1)6-253
2)241
3)491
4)181
1)6-221
2)860
3)496
other products; a permis-
sible antioxid*ant for
aviation gasoline; plastt-
cizer for cellulose ace-
tate; int for ancioxidanta
special searches, oil-
soluble phenolic resina;
pour-point depressors &
emulsion breakers for
petroleura oils & sot.te
plaacics; syn lubricancs;
tr.aec; ind odoranta
-------
A-t'J
TAV.U: A.I. (Cunl limed)
i.« ' Sir1:,;'
No. . Formula
79 tcre-Bueyltoliiciw
(r»luenc, ten-Butyl-)
C4119C6"4C!S
80 n-ButyrjUehyde
CHJ(CH2)2CHO
'
Clivo. Al'.'ur.
Rcgisirv No.
IVL.N)
000043511
(IXKD)
0001 J3 72 8
(VH3)
Or:ll Tuxlclly. Toxic '.!;I?IIM| K.lllnit
LU50, »»., KH Aoltc (;|UV;.U.
1500 orl-rat L)irr-2 L)lrr-2
900 orl-nus S)ln;-.-3 S)inK-3,
2000 orl-rl>t lhl-3 itil-3
skn skn
obs-2 al.s-2
2490 orl-rat L)irr-2 L)irr-l
ing-2 S)i:
ihl-2
S)inS-2
To\iv'olo^v TLV Ciirclnoscn
TCI*: 10 ppn/3M, u^OS air:
TKX:1RR, iltl-hmn TWA 10 ppn
TCLo: 20 p;-a/3M,
TFX:CNS, ihl-lwin
Irr Co lungs ; CNS
depressant; liver
& kidney damage
after prolonged
exposure
LC50: 1500 cii/a3
4H, ihl-r.nt
LC50: 248 ppu/2H,
TCLo: 5SO ag/m3,.
TFX:IKK, ihl-hmn
LD50: 2400 mg/kg,
scu-=us
lhl-2
81G Butyric acids
CHJ(CH2)2COOH
81 n-Eutyric acid
.^H8°2>
82 n-Butyric anhydride
000107926
(QV3)
2940 orl-rat
(Kef 2)
8790 orl-rat
(Ra£ 4)
LDLo:5(50 orl-
tnus
LDLo:3600 orl-
rbc
L)irr-l
lng-1
ihl-1
S)inS-l
ihl-1
L)irr-l
S)U
83 n-Butyronttrile
000106310
(3VOV3)
000109740
(NC3)
LDLo: 50 orl-
rat
LDLo: 100 orl-
mus
84 Carbon disulfide
(CS2)
000075150
(SCS)
65 Carbon 'tocrabroaide
000558134
(EXEEE)
LDLo: 1000
orl-rat
L)irr-l
ing-l
lhl-1
ihl-1
L)irr-l
S)U
L)lrr-l L)U
lng-3 S)ing-3
lhl-3 ihl-3
skn skn
abs-3 abs-3
L)lng-2
lhl-2
S)ihi-2
L)irr-l
S)U
LD50: 3180. mj/kg,
Ipr-aus
LD50: 3180 mg/kg,
LD50: 800 ng/kg,
Ivn-cus
Anlnal experi-
ments show high
toxiclty similar
to cyanides;
poison
LCLo: 400 ppm,
Ihl-rat
LD50: 500 mg/kg,
skn-rbt
LCLo: 4000 ppo/
30M, ihl-hran
TCLo: 50 rag/n3/
TC; TFX:CNS,
ihl-hmn
CNS effect, narco-
tic & anesthetic,
respiratory fail-
ure; death; per-
manent damage may
occur in cases of
chronic poisoning
LDLo: 300 ng/kg,
scu-rbc
LDLo: 400 ng/kg,
Ipr-rac
Narcotic in high
concen
LDSO: 298 pg/k?.
acu-aus
USOS air: TVA
20 ppo; Cl 30
ppm; Pk 100
ppra/30M/3H
air: TWA 100
PPO
-------
Sources of
Process
tip.
Pi'ocosa
Waste
Tivnt nu'tit
Total
Production
Uso.i
Roforcnecs
Alkylatijn
Cere-butyl alcohol,
Coluem:, jiuliurlc
acid
Wn tor: sodium hydroxide,
tcTt-butyl toluene
Solv; InC
1)6-21}
2)1139
3)498
Crotonaldchyde, 77
hydrogen
Hydrogenation
Air: crotonaldehyde,
buCyraldehyde
216 Polyvinyl butyral; bucy-
(477)- race plastics; coating
1973 fabrics; rbr accelerators
1)6-257
2)255
3)499
9)203
Propylcne, syn, 260
gas, tolueno (solv)
211
Oxo process
AtrI CO, propylene,
propane
Enission factors:
CO - 4.0, prcpylene
1.0, propane - 1.0
Light ends r.ay
be flared
.(See Acetic Acid)
Molded & extruded products;
lenses; cable Ucq; fishinj
e^uip; flavors: pharm
1)6-257
2)255
3)500
7)3-873
12)
1)6-719
2)255
7)3-831
n-butyraldehyde, 73 Oxidation Air: n-butyraldehyde,
air or oxygen butyric acid
Emission factors:
hydrocarbons - 2.0
Syn of butyrate ester
perfuae & flavor ingred;
ph.trrt; delloing agn; dis-
infectants; emulsifying
agn; sveetening gasolines
1)6-259
2)255
4)134
6)6-719
7)3-881
12)
Tutyric acid, acetic 265
acid or acetic anhy-
dride
Exchange Air & Water; acetic
acid, acecic anhydride,
butyric acid, butyric
anhydride
M£r of butyrates; drugs,
tanning agn
1)6-883
3)500
n-propyl chloride,
sodium cyanide,
n-propyl alcohol
217
Substitution
(Displacement)
Water: NaCl, propyl
alcohol, proayl chlor-
ide, butyrontcrile,
sodiua cyanide
Air: propyl chloride,
propanol, hydrogen
cyanide
Basic ntrl in ir.d. chen & 1)6-735
phara iut products; poultry 2)259
medicines 3)500
Methane, sulfur
155
Substitution
(Sulfiding)
Air; sulfur, H2S, S02,
gaseous hydrocarbons,
CS,
352.9
(777.4)-
1973
355
(782)-
1974
218
(479)-
1975
Mfg: 397. viscose rayon, 147.
cellophane, 257. carbon recra-
chloride; flotation agn;
veterinary medicine; solv;
rbr accelerator
1)6-497
2)293
3)520
4)208
6)615
7)4-384
11)37
13)31
llethane, bromine
157
Bronination
Air: bromoroethanos,
hydrogen bromide
Org syn
1)6-503
2)295
3)521
-------
TAiuj-: A-i. (i:,i,ii ir..,,-.;)
Ufa
N>.
86
CotliiioutiJ
Kami' an.l
Forir.ii 1:1
Carbon tccrnclilnr tile
(cci4)
Clu'-i'.i. rth.;ir.
Hfgliil rv Mu.
(U.N)
ooour.i^J5
(CXCtH!)
Ornl Toxl;;0, fv./lti'.
1770 orl-rat
6J80 orl-rbt
Toxic M.i-Mr.l Bailiu;
Ak-iiti- Clii-inili- ToxU-olixv
I.)0 t.)lrr-l TCLo: 20 p|-ai.
S)iiii;-3 S)lnn-3 TFX:CNS,
i!ll-3 Jlll-1 11,1-llMK,
Tl.V
i:SOS nJr: TWA
10 ppiu; ('5 r.i£/(a^
CL: 25 pun
Cari- tii|..'.-r^ta
A
intx>: '.SOi^^^k-
R.sul, TFXiCAU,
skn t:k«
nbs-1 al>s-3
LCU.: 10UO ppn,
llll-hmil
Narcotic; Jcuth
results ilna Co
respiratory fail-
ure; in oa:-es cluic
recover, serious
kidney, Iiver &
Lung pm/UMt;.'/40
I!K or 12.d ng/n^
TDI,j: 133
25'.J1, TFX:Mi;0
scu-rat
TDLo: 31-80 mg/k-
30'.n, 1FX:CAR.
orl-ham
TDLo: 159 Rr.i/kg,
25WI, TFX:CAR,"
fcu-rnt
TDLO: 159 Sm/kg/
20UI. TFX:CAR.
rec-rmis
TDLo: 120 mg/ks.
8SDI, TrX:C,\R,
orl-mu3
87 Cellulose acetate
009004357
Unknown
83 Chloranll 000118752 4000 orl-rat
DP (P-Benzoquinone, 2,3,5,6- (L6V DVJ-/G4
tetrachloro-)
89 ChloroaceCic acid 000079118 76 orl-rat
DP (Acetic acid, chloro-) (QVIC) 165 orl-BUS
CH.,C1COOH
L)irr-2 L)U
S)ing-3 S)U
ihl-2
CNS depression,
irr to skn &
roue mem
LDLo: 500 mg/kg,
ipr-rat
LDLo: 4 oj/kg,
ipr-mus
LD50: 5
scu-rat
LDLo: 500 mg/kg,
ipr-mus
90G
Chloraauilines
(Aniline. Chloro-)
SO m-Chloroanlline
(Aniline, o-Chloro-)
'
91
92
o-Chlorojntllne
(Aniline. o-Chloro-)
p-Chloromlline
(Aniline. p-Cliloro-)
(C61I6C1H)
000108429
(ZR CO)
000095512
(ZR EC)
00010647&
(ZK DC)
300 orl-rat
100 orl-nus
100 orl-bd«
S80 orl-rat
256 orl-nus
300 orl-rat
100 orl-mus
' 100 orl-bdw
L)alr-l
ing-3
ihl-3
skn
abs-3
L)alr-l
S)ine-3
ihl-3
skn
abs-3
L)alr-l
S)ing-3
ihl-3
L)olr-l
S)inis-3
ihl-3
skn
abs-3
L)alr-l
S)in3-3
ihl-3
skn
abs-3
L)alr-l
S)ln;:-3
ihl-3
TCLo: 44 ns/mj
1TX:BLD, ihl-hon
LDLo: 310 mg/kg.
scu-cat
LDLo: 310 [tig/kg.
scu-cat
.TCLo: 44 mg/m3,
TFX:DLD, ihl-hmn
LD50: 420 ns/fcg,
ipr-rat
LDLo: 125 mg/kg,
scu-cat
LUIo: 36 ng/kg.
skn-rbl
-------
Proci::.:;
NI-.
WM s t»!
Tri-:iti:t.-:K
Total
Pri>>!-.!»-t I.i
dU-Morldc, niA,
chlorine UK:
Ch lot" tn.it Ion
f. Pyivlysis
Air: ch I orohyvf voc.tr-
chloride
Heavy cnJa 476 rlfj;: v:~ Kroon H. :'K" I'tvon 1)6-'.17
usu.itly (10'.7)- 11; ru-t.il J.'/.ri-'.nsliu-.; a>;ricul- l)d-t,22
inclncrateJ 1973 tur.il final i;:mt; clilorinac- 2)295
529 in>; civs CDmponnJs; proJuc- 8)8')
(1163)- tinn oC scnicoinluctors; 13)31
1974 clcaiiin,; .:i8u; fire extin-
413 Ktilshcrs; in::ec; flour
(90S)- blcac'li iui;; pharni; [ictro-
1975 leum reliuir^;; lubricai-.t
Ethylene dicliluride, 13ID
hydrogen chloride,
air
LPC or natural gas- 218
ethane, propane,
chlorinet sodium
hydroxide, inhib
r^Chane, chlorine 158
Chlorlnatlon
& Tyrolysis
Clilortnacion
(Chlorinolysis)
ChlorinaCion
See above
See above
Air: various
chloromechanes
See above
See above
See above
D6-A21
3)17; 522
6)618
1)6-737
7)5-137
1)6-505
Cellulose, acetic
acid, acetic
anhydride, sulfuric
acid, sodiun ace-
CaCe, sodiun bicar-
bonate
91
AcetylaCion
Water: degraded cellu-
lose, sulfuric acid
Air: various solv
Emission factors:
Hydrocarbons - 10.0
378.9 »fg: 487, acetate fiber; 1)6-293
(834.5)- 20?. photo film, trans- 3)527
1973 parent sheeting, therao- 6)615
plastic aolding composi- 12)
tion; 247. cigarette 13)31
filters; lacq; protective
coating solutions
1,6-trichtoro-
Inol, chlorine,
fuming sulCuric acid
282 Oxidation Water; 2,4,6-trichlorb-
(Chloroxidation) phenol, other clorophe-
nols, chlorine, sulfuric
acid, chloranil
Agricultural fungicide; 1)6-927
dye int; electrodes for 2)195
pH measurements; vulcan- 3)1147
Iring aga
Acetic acid,
chlorine
93
ChlorinaCion
Acetanilide,
acetic acid,
chlorine
Chlorination
& Hydrolysis
Water; hydrogen chloride,
chlorine, sodium hydrox-
ide, chlorinated bypro-
ducts
Air; acetic acid, chloro-
acecic acid, chlorine,
hydrogen chloride
Emission factors: hydro-
carbons - 2.0; HC1 - 4.0
Air: chlorine
29.1 Mfg: 507. herbicide, 407. pro-
(64.2)- duction of carboxyir.ethyl-
1969 cellulose; ethyl chloro-
acetate, glycine, syn
caffeine, sarcosine,
thioglycolic acid, EDTA,
,2,4-D, 2,4,5-T; syn dyes;
medical & pharoi
Dye int
Int for azo dyes & pig-
ments; pharm; insec;
agricultural checn
1)6-303
2)15
3)941
7)8-417
12)
1)6-81
2)106
7)2-419
2)106
3)542
See chloroanilines above
Dye int; standards for 2)106
colornctric apparatus; 3)542
mfr of petroleum solv
& fungicides
See chloroanillnea above
Dye Int; pharm; agricul-
tural chcm
2)106
3)542
-------
A-M
TAI11J-: A-l. (<:,,iiiii.u.-.l)
ltt-m N.itm! ond
No. F.-rr.uln
93 Chlorobcr.:.ililehy.!''>'
00009S3H4
(VIIK XC)
00010S907 2510 orl-v.-it
(CR) 2SJO orl-rbt
T.-xK. l!.i:-.ir.l K.ntnv;
' AcnU! C!in-::L.-
L)lrr-l L)0
In^-1 S)in3-2
ihl-1 i!il-2
S)lnj;-2 skn
llil-^ abs-2
ekn
abs-l
ToxU'rIoijv TI.V Cnrclnoften
Scrc-.'.s narcotic USOS air: TWA -- .
with only slight 75 ppn or
Irr o,ii.ilictcs. 350 oig.'m^
Prolonged expo-
sure ri.^y cautfe
kidney 4 liver
dnru^e
LDLo: 4000 rig/kg.
scu-rat
95 Chlorober.:otc acid 026:64095
DP(,p)(3etuolc JCid, chloro-) (QVS XG)
96C Chlorober.zoyl chloride
(Bensoyl chloride, chloro-) (OTS XG)
ClC^COCl
(C?H4C120)
96 Chlorobe«oyl chloride a- OOOolS452
DP . (GVR CG)
97 Chlorobetzoyl chloride o- 000'509654
(CVR BG)
98 ChlorobeMoyl chloride p- 000112010
(GVR DC)
99 Chlorodifluoroechane ,. 025-197294
(Ethane, chlorodifluoro-) (GXF?)
L)lrr-l
ihl-1
S)lhl-2
L)irr-l
S)U
100 Chlorodifluoromethane . 000067663
(Methane, chlorodifluro-) (GYFF)
CIHCF,
(CHC13)
101 Chlorofora
000067663
(CYC-C)
800 orl-rac
LCLo: 2400
orl-mus
LDLo: 1000
orl-dog
L)irr-l L)l'
S)ihl-3 S)U
Asphyxiant in high
concon
TCLo: 10 ppn/lY USOS air: TWA
TFX:SYS, ihl-hmn 50 pra or
Anesthetic; paral- 240
TCLo: 18 era/kg/
120DI, TFX-.CAR,
orl-oius
ysis & death.
Narcotic, danage
to liver & heart.
LCLo: 8000 ppra/
4H, ihl-rat
LC50: 28 ppra,
Ihl-r.us
LD50: 704 Kg/kg,
scu-^us
LC50: 100 ppo,
ihl-dog
LDLo: 75 mg/kg,
ivn-dog
LC50: 59 ppa,
ihl-rbt
LDLo: 800 ms/kg,
scu-rbc
LCLo: 20,000 ppra/
211. Ihl-gpg
KIOSH rec
USOS air: WA
10 ppn-10 hr
-------
Sources of
Compound
^^Ht>ro to luvne ,
^^Worlne
L'rovesii
No.
334
P roc oss
Chlorin.itloti
& Hydroly^ia
A:v"^;''"J
Wacpr: c1ilorotvnz.il-
chlurldo:', cliloru-
Tr
toluenc:!, aldehydes
Air: chlorine
Total
Production
Inc In Che prep of trl-
phonyl ncthanc i relate^
dyes; org inc.
Rt'fi'i'ences
1)6-1071
Benzene, chlorine,
6c>duira hydroxide
catdlyst
Chloriiucijn
Air: benzene, HC1
Water: HC1, diclilorj-
benzenc
Emission factor*:
benzene - 7.4, ulhyl
chloride - 1.3, ethyl-
enc dlchlori.lo - 0.1
180.5 Syn: 50". nitroclvtorobenienes, 1)0-55
(397.5)- 207.'solvent, 10" phenol, DUf; 2)164
1973 solv carrier for methylcna 3)542
dllsocyanJCc; Inc. & solv; 5)560
dye Int; Insect repcll- 6)617
ones; dielectrics; lub- 7)5-265
ricaeins oil additive; 9)22
coolant in the electrical 12)
Ind 13)31
p-chlorocoluene
chlorine,
caCalysc
Chlorotoluene,
chlorine,
catalyst
335
336
Chlorlratlon
4 Hydrolysis
(Oxidation)
Chlorlnation
& Hydrolysis
(Replacement)
Air: HC1 «, Cl.,
Water: chlorobcnzoic
acids
Air: HC1, Cl:
tiater: chlorobenzo-
trichloride, chloro-
toluene, KC1
Int for the pre? of dyes, 1)6-1073
fungicides, phara & other 7)3-A37
org chem; glues; paints;
fungicide; plant growth
regulator
Int for pharm, dyes & 1)6-1075
other ors chen
ifluoroethane
169
Chlorination
Air: chlorine,
chlorinated compourds
Water: KaCi, NaOH
Kfg: 52T. aerosol propellant, -1)6-547
297. refrigerant, 97. foaa 3)545
blowing agent, Disc 13)31
Chloroforn,
hydrogen fluoride
Methane, chlorine
161
160
Substitution
(Fluorination)
Chlorination
Air: chlorofluoromethanes
Water: KC1, NaOH, KaCl
Air: chloromethanes
Wacer: NaOH, salts, acids
Emission factors; cethyl
chloride - 26.0, rnethylene
chloride - 4.0, carbon
tetrachloride - 2.0,
chloroform - 2.0, nethane -
2.0
115
(252.8)
1973
134.0
(295.2)-
1974
Mfg: 527. aerosols; 297.
refrigerant, 97. foam blow-
ing agent; chea int
Mfg: 52Z fluorocarbon refrig-
ants & propella-ts (CHC1F,);
417. fluorocarbor. plastics';
dyes & drugs; general solv;
fuoiganC; anesthetic
1)5-515
2)709
3)545
7)5-126
13)32
1)6-513
2)314
3)547
5)560
6)613
7)5-126
12)
13)32
-------
Icon
So,
102C
102
103
104 C
(P)
104
DP
105C
105
106
DP
107
D?
108
109
DP
110
DP
me
.
Compound
N.itni* nnd
F.Tirula
Cliloronurhthalencs
Naphthalene, 1-chloro
Naphthalene, 2-chloro
(C10H7C1)
Chloronitrobenze-es
(Bcmone, chloroaitro-)
C1C,H,NO.
(C6H4ClN02,p-)
Chloro phenols
(Phenol, a-chloro-)
(Phenol, o-chloro-)
(Phenol, p-chloro-)
C^CIOH
(C6H5C10)
m-Chlorocoluene
(Toluene, n-chloro-)
(C7H7C1)
o -Chloro toluene
(Toluene, o-chloro-)
p-Chloro toluene
(Toluene, p-chloro-)
Cresyllc acid
(Cresol)
C,H,OHCE
(C H 0)
Chcm. Ahsti-,
Rctit.nry No.
(KIN)
OOOC90131
(U6J BG)
000091587
(L66J CO)
025167935
(WNR XG)
(WNR DO)
000108430
(QR CG)
000095578
(QR SC)
000106489
(QR OG)
000108418
(CR C)
000095498
(CR 3)
000106434
(CR D)
001319773
(QRX)
Oral Toxlsitv, Ti>xlc Snruril U.illiu:
U>50. !:'!'-'k-1 Ao.U- Chronic
1540 orl-rat
1091 orl-aus
207S orl-rat
836 orl-mus
L)U L)V
S)ins-3 S)ins-3
lhl-3 ihl-3
n ii
570 orl-rat l)lrr-3 L)U
lng-3 S)ing-3
lhl-3 ihl-3
S) ing-3
thl-3
670 orl-rat " "
670 orl-mus
'
500 orl-rat . " "
(Ref 2)
670 orl-rat
(Ref 4)
-
.-
--
1454 orl-rat L)irr-2 L)lrr-3
861 orl-reus alr-l alr-1
ing -2 S)ing-2
lhl-2 lhl-2
S)ing-2 skn
lhl-2 abs-2
skn
aba -2
Toxtcolorv TLV
TFX:SVS, ihl
damage to liver
Cumulative effects.
Kothcnoglobin,
cyanosis & blood
changes
"
L050:' 355 mg/kg,
ipr-rat
LD50: 1390 o3/kg.
scu-rat
LD50: 230 mg/kg.
Ipr-rat
LD50: 950 mg/kg.
scu-rat
LDLo: 950 ng/kg,
scu-rbt
LDLo: 800 mg/kg,
scu-gpg
LD50: 281 ns/kg.
Ipr-rat
LD50: 1030 mg/kg,
scu-rat
Narcotic In high
concen. Details
unknovn
Unknown
ii
Corrosive to skn USOS air: TWA .
& mucous mem. 5 ppci (skn)
Abs nay result in or 22 cg/m
kidney, liver &
CMS damage
Card
.,
m.
--
TDLo:
12HI,
skn-mu
__
1
-------
A'(,
Sourc « s o t* Process A;: sue i ,-t I ed Wa s t «
C«»:r.poun-t No. Process Wii^cc* TiVjitr.iMtit
ithalcne, 193 Chlorin.ition W.-iter: NaCl. NaOH.
>rine, nnplalui U*ne , chlorinated
e^xliura hydroxide napththalcne»
Mr: chlorine
Total
Production Use,i Rt'f*?rt'nct!S
Wax; electrical condenser 1)6-671
impregnation; moisture-, 2)772
flame-, ncid-, insect-proof-
ing of wood, fabric & other
fibrlous todies; cois-
Curc-, & flame-proofing
covered wire & cable;
sol '(for rbr, aniline
& Other dyes; mineral
& vegetable oils, var-
nish gums & resins, &
other waxes when nixed
in the tulcen state
Naphthalene, chlorine 193
Chlorin.ition
2)772
Chlorobenzer.e,
nitric acid
Nitration
Air; aroma ties
Emission factors:
chlorobenzer.e - 3.2,
HO, - 0.9, r.icro-
. chlorobenzend -0.1
63.6
(140)-
1974
Int, especially for dyes; 1)6-61
nfr of p-nicroplienol, from 3)549
which parachion is oad« 12)
Phenol, chlorine,
sodlura carbonate,
hydrochloric acid
Phenol, chlorine,
sodium carbonate,
hydrochloric acid
281
281
Chlorlnation
Chlorination
Water: NaCl, HC1,
phenol, chlorine,-
chlorophenols
Air: C12, HC1, solv
Emission factors:
Cl2 - 2.0, carbon
tetrdchloriia - 1.0,
phenol - 1.0
Int In org syn, e.g., drugs; 1)6-923
fire retard.tnc phenolic 2)361
resins 12)
Dye Int; syn higher 2)361
chlorophenols
Phenol, chlorine,
sodium carbonate,
hydrochloric acid
281
Chlorination
Int syn dyes & drugs; 2)S6l
alcohol denaturant; selec- 3)551
tive solv mineral oil 4)245
refining
m-toluidine,
sodium nitrate,
hydrochloric acid,
cuprous chloride
Toluene,
chlorine,
iron catalyst
332
333
Sandmeyer
Reaction
(Replacement)
Chlorination
Solv; Int
Solv & int for
org chem & dyes
1)6-1067
3)555
1)6-1069
3)556
Toluene,
chlorine,
iron catalyst
333
71
Chlorination
Springing &
Separation
Emission
^
K02 - 4.2, hydro-
carbons - 2.0
Solv & int for 1)6-1069
org chc.Ti & dyes 2)1139
3)556
35.9 221 Phosphate esters; 157. 1)6-233
(79.0)- phenolic resins; 15^ la=iin- 2)350
1973 atea coatings for magnet 3)580
wire for snail electric 5)560
motors; 157. antioxidants; 6)620A
67, disinfectants; 61 ore _ 12)
flotation agn; org int, 13)32
wire enamel solv, plastic-
izers, gasoline additives
mecal cleaning corapoun^s.
surfactants, oil additives,
eotv refining of lubrica-
ting oils, ocouring coct-
pountls, pesticides
-------
TABU: A-l. (CunUnm-.l)
Cx^nipound
Item N.i:n«! auJ
So. Ft'rnuln
1UC Crx.-f.oU, oUed
111 m-Cresol
DP (CJLO)
/ o
112 o-Cresol
DP (C7HS°)
113 p-Crcsol
DP (C H 0)
r
114 CroConaldehyde
CHjCHCIlCKO
(C H 0)
46
Chcm, Abstr,
Registry ilo. Oral ToxUllv. T.'xlc l!.lr:ir,l K.-:t!i>:-,
C.'I.N) L1IM' "'K'"* Aculo Chtv.ilv
.-
(QR X)
000103394 2020 orl-rac L)irr-2 L)irr-3
(QR C) (Kef 4) alr-1 a!r-l
242 orl-r.it lng-2 S)ii-.,;-2
(Ref 2) ihl-2 ihl-2
823 orl-mus S) ing-2 skn
LDLo: 1400 ihl-2 abs-2
orl-rbc skn
aba -2
00095487 1350 orl-rae " "
(QR B) (Ref 4)
121 orl-rac
(Ref 2)
344 orl-mus
LDLo: 940
orl-rbc
000106445 1800 orl-rac " "
(QR D) (Ref 4)
207 orl-rac
(Ref 2)
344 orl-mus
LDLo: 620
orl-rbc
000123739 300 orl-rac L)lrr-3 L)alr-2
(VH1U2-T) 6 orl-iuus alr-2 S)U
ing-3
ihl-3
S)U
Tuxlcolofv T!.V i*~r..i.,
1^ . E^i^^kB
LD50: 620 niS/kg, USOS oi-.-: IMA.
skn-ral 5 ppm (skn) or
LD50: 2050 ns/ks. 22 rag/tr1
skn-rbc
LDLo: 450 res/kg.
scu-:nis
LDLo: ISO *s/kB,
SCU-C.lt
LD50: 2050 as/kg,
skn-rhc
' LDLo: 500 Kg/kg,
scu-rbc
LDLo: 280 r.s/kg.
. ivn-rbc
. LDLo: 100 nj.'kg,
ipr-spg
LDLo: 250 ms/kg.
scu-frg
& mucous moo.
Abs cay resulc in
kidney, liver &
CiiS damage
LD50: 1100 c;/kg,
skn raC
LDLo: 410 mg/kg,
SCU-3US
LDLo: 55 mg/kg,
scu-cac
LD50: 1380 mg/kg.
skn-rbc
LDLo: 450 mg/kg,
scu-rbc
LDLo: 180 ms/kg,
ivn-rbc
LDLo: 360 mg/kg,
ipr-gpg
LDLo: 200 ng/kg,
scu-frg
Corrosive Co skn USOS air: TWA
& mucous men. 5 pptn (skn) or
Abs aay resulc in 22 nj/=3
kidney, liver &
CHS damage ' -
LD50: 750 mg/kg.
skn-rac
LDLo: 150 mg/kg,
scu-nus
LDLo: 80 mg/kg,
scu-caC
1X150: 301 mg/kg,
skn-rbc
LDLo: 300 mg/kg,
scu-rbc
LDLo: ISO mg/kg,
ivn-rbc
LDLo: 100 mg/kg,
Ipr-gpg
LDLo: 150 mg/kg.
scu-frg
TCLo : 4.1 pptn,
TFX-.IRR, Ihl-hnn
LachrymaCor;
scrong irr; nay
cause corneal
burns
LC50: 4000 nj/nV
30M, ihl-rac
LD50: 140 m;;/kg.
scu-rac
LC50: 1510 ns/ro3/
21!, Ihl-mus
LD50: 160 roz/kE,
scu-rac
Ll)50: 30 mg/ks.
skn.gpg
-------
A-JB
Sources of . Process
Coiiit-ouiul IJn. Process
71 Sprlnc!R;4 &
Separation
Refinery caustic 71 "
extract, flue gas,
isobutylcue
A
Kmlssl;
Wn.1t.
u fnc-
tL'J «.1Ht«
s TiVilCmi.-nt
torn: NO., -
4.2, hydrocarbons - 2.0
Air & W:itc:r: cresols.
phenol
Emlsslo
NO, - 4
2.0
n fnc
rors-
.2, hydrocarbons -
To tu I
Piv.l.icl loa
41.8
(92.0)-
1973
Total n,
0, p-
crcsol
52. /,
(115.4)-
1973
Slrallar 1
Slnilar
Disinfec
resins ;
ph.tte; o
textile
org int,
Uses
o cresylic acid
o cresvltc acid;
:mt; phenolic
vicresyl plios-
c floC.icion;
courluj:; agr\;
tr.fs oC
References
12)
1)6-233
2)350
4)293
5)560
6) 620 A
7)6-442
sallcyl.ijohydc,
counurin, ft herbicides,
food antioxidants; sur-
factant; nulding com-
pounds; adhesives
12)
71
11.2 Sinilar Co cresylic ac£d;
(24.7)- org syn salicaldshyde,
1973 coumarin, misc
1)6-233
2)350
3)579
4)293
5)560
71
Sijnilar to cresylic acid
1)6-233
2)350
3)580
4)293
5)560
Acetaldol
76
Dehydration
Wate
aldehyde,
acctadol, crotonald-
ahyde
Emission factors:
acetaldehyde - 1.00 Ib/ton
Keavy ends
incinerated
Int for n-butyt alcohol
& 2-ethyl-hexyl alcohol;
solv; preparation of rbr
accelerators; purifica-
tion of flubricating oils;
inoec; tear gas; fuel-gas
varnlns agn; org syn;
leather tanning; alcohol
denaturant
1)6-255
2)353
3)580
12)
-------
A-.''I
TAIlI.K'A-1. (i:,ut! liiiu-j)
Item
XD,
Hi
116
117
118
119
120
121
DP
122
N.I.;!.: ami
F.inir.ll:l
Cro Unite :tclJ
CH..CUC1K*OOU
J
CjlljCll(CII3)2
//» 11 \
(C9ii12)
Cumene hyJroperoxide
(HydrvporoxIJe,
o.a-ditnethylbenzyl)
(CH3)2C(C6H,.)OOK
(C H 05
* 9 12 2'
Cyanoacetic acid
(Acetic acid, cyano-)
CNCHjCCOH
Cyanogen chloride
CNC1
(CCIN)
Cyanuric acid
(S-Triazine-2,4,4-triol)
(C3H3N3°3)
Cyanuric chloride
(S-Triazine-2,4,6-
Crichloro-)
(CjCljNj)
.
Cyclohexane
(C,H )
Cli-'u. Ahstr.
Ki-<'.lstrv No. Oi-'il Toxli-Uy. Toxic l!nr..-iril K:illm-
(ULN) '-"jO- "'/k>'- Aciilc ClifiMilc
0037^46SO 1000 orl-vat
WVIU2-T
000093328 2910 orl-rnt L)lrr-l L)irr-2
(1YR) (Kef 4) S)lnt-3 S)ins-.'
1400 orl-rac itil-3 ihl-2
(Re£ 2) skn skn
abs-3 nbs-2
OOOOS0159 332 orl-rat L)irr-3 L)U
(QOXR) LDLo: 5000 ing-3 S)U
orl-mus ihl-3
S)inS-3
ihl-3
skn
abs-3
000372098
(QV1CN)
000506774
(G CN)
000103305
(T6N CN ENJ BQ
DQ FQ)
000108770 435 orl-rac L)irr-2 L)alr-2
(T6H CN alr-2 S)U
E!U BG S)ing-2
DC FC) ' ihl-2
irr-2
OOOU0827 -' 1297 orl-mus L)lrr-2 L)U
(L6TJ) LDLo: 5500 S)Ihl-2 S)ihl-l
orl-rbt
Toxtceloav TI.V
UTjQ: COO nv;/ks.
skn-sps
Unknoviii
Potent narcotic I'SOS air: TWA
with Ipn^-durjtiun 50 ppoi (skn) or
effects. CNS i!o- 245 mg/rr3
prcssant. Possible
cumulative effects
LC50: SOOO ppn/Ail,
ihl-rat
LCLo: 2000 ppra,
ihl-raus
LC50: 220 pfo/iil,
ihl-rat.
LDSO: 95 ng/kg.
ipr-rat
LDSO: 400 ng/ks.
scu-rat
LDSO: 200 ppra/4H,
ihl.-B!U3
LDLo: 90 ng/kg.
ipr-mus
Highly toxic
LDSO: 200 rag/kg,
ipr-cus
Highly toxic
LC50: 118 ppfj/3ttt;
ihl-rat
LC50: 117 ppo/30M,
ihl-cus
LDLo: 39 ng/kg.
scu-cus
LCLo: 79 ppn/SH,
ihl-dog
LDLo: 5 ng/kg.
scu-dog
LC50: 207 ppn/30M,
ihl-rbt
LDLo: 20 ms/kg.
scu-rbc
LC50: 207 ppra/30H,
ihl-gpg
Highly toxic
irr to mucous
mem; causes heart
erhychnia in hcins
skn irr; USOS air: TWA
asphyxianc 300 ppm or
LDLo: 77 ng/kg, 1050 cg/nP
ivn-rbc
_Cnrc_lno^i^^__
TDLo: 304 mg/kg,
TFX:KEO. ihl-nus
TDLo: 10 £o/kg/
76WI, TFX:SEO.
scu-mus
..
-
TDLo: 18 mg/kg/
73W, TFX:NEO,
unk-rat
TDLo: 22 £ra/kg/
73UI, TFX:KEO,
orl-rac
TDLo: 750 mg/kg.
TPX:NEO, scu-rat
-------
A-JO
SuurcfJ ot Process AssociiiU'J
Coni|iot:
-------
A-II
TAI1I.K A-l. (Coiltiiir..-.!)
Compound
3 ten N.tcu1 nnJ
No. JVrir.ti I.T
12J CyclohoxAnol
rp c'n.,011
0 11
/.- ii rt\
(l-b"l20)
Cliorj. A!>slr.
RL'nisiry ;.'o.
0-'I.N>
0001 OR "30
(I.&TJ AlJ)
Or:il Tonic itv,
LIV)0, .,1:i/k,:-
2060 orl-rat
LJ>UJ: 1300
orl-doc.
LDLo: 2200
orl-rbt
Trtxio M:i:r:ir:l K.illmj
Acild1 I'iito.lU-
L)Irr-l
Ihl-1
S)l.,,-.-2
llii-2
skn
abs-1
Tox{colO'-,v Tl.X' Cnri'li\v>^o^^^
TCIo: 100 p|x:i, USOS air: TWA Suspected cnrltiogen
TFX:MMI, Ilil-hicn 50 ppc:i or
Narcotic; kiJncy, 2CO ms/n3
liver i bli>i.-.l
vessel il;n:ui.;o in
cx|vr in:cntal
animals
U)Lo: SOO in,: -'kg.
scu-cat
LDLo: 1420 nj/kg.
ipr-rbt
124 Cyclohexanone
DP cb(Cii.2)4cn2
000103941
(L6VTJ)
1620 orl-rat
LDLo: 1300
orl-mus
LDLo: 1600
orl-rbt
L)irr-2 L)irr-l
S)inS-l S)ing-l
ihl-1
TCLo: 50 ppm,
IFX:IRR, ilil-tuin
Death after lung
exposure. Irr to
eyes & throat;
mild narcotic
LCLo: 2000 ppcn/4H,
ihl-rat
LD50: 1350 oj/kg,
ipr-mus
LDLo: 630 mg/kg,
ivn-dog
LD50: 1000 mg/kg,
skn-rbt
USOS air: Ti.'A
50 ppra or
200 mvj/m3
125 Cyclohexene
000110838
(L6UTJ)
L)ihl-2
S)ihl-2
IOU
S)U
USOS air:
300 ppm or
1015
116
DP
Cyclohexyladine
(C6HUN)
000108918
(L6TJ AZ)
710 orl-rat
L)irr-2
S)ing-3
ihl-3
skn
abs-3
L)irr-2
S)ing-2
ihl-2
skn
abs
Dernatltis &
convulsions
LCLo: 8000 pfm/
4H, ihl-rat
LD50: 200 rag/kg.
Ipr-rat
LD50: 300 mg/kg,
tpr-mus
LD50: 320 mg/kg.
skn-rbt
LDLo: 500 ng/kg.
par-rbt
USOS air: TWA
10 ppm (skn)
or 40 rag/nP
127 Decahydronaphth.ilenes
(Naphthaline,
decahydro-)
000091178
(L66TF)
4170 orl-rat
L)irr-2 L)air
ing-2 S)U
S)ing-2
Irr to eyes, skn,
fit muc mem. Kidney
damage in exper-
imental animals
LCto: 500 ppm/
2H, ihl-rat
128
Dccanol
(Decylnlcohol)
000112301
(Q10)
4720 orl-rac.
Unknown. Exper-
imental animals
suggest low
toxicity
LC50: 4000 mg/m3,
ihl-mus '
-------
Sourci1* of Process
^ Comnn«iiJ No.
air, catalyst
Phenol, hydrogen, 289
be nz -Aldehyde,
sodium hyJroxide
Cyclohcxanol, 42
air
11 290A
2908
290C
290D
Cyclohexanol, 43
phosphorus
tribromide,
arcnonla
fllne, 17
hydrogen,
catalys t
Process
Oxidation
Hydroge nation
Oxidation
ii
"
Dehydration or
substitution &
elimination
(dehydration or
anmonolysis)
Reduction
Wn.stfS Ttv;it ri.'iir
Al rl cyclohos-mo ,
residual cruJo
.
Air : phe no I ,
eye lohexanol ,
cyclohi-'xanoi'.e
Water: taOH.
bcnzaldehyde ,
eye lone xanone
Air ; cyclohexane,
residual crude
n __
Air : cyclohexanol ,
cyclohexanone
Emission factors:
CO - 1115, hydro-
carbons - 100.7
.
Air; arosiatics.
hydrogen
Emission factors:
eye lohexanol - 1.0
To tii I
Ptviluci Ion
325.5
(716.9)-
1968
"
239.7
(638.2)-
1071
J.7 / J
11
II
965
(2123)-
1973
1068
(2352)-
1974
805
(1773)-
1975
"
Uat-s
H£g: 90Z ftdtpfc acid for
nylon; so.ip nukin>;; to
Incorporate aolv & phenolic
Insect; textile finish-
ing solv; blcnJiug agn;
lacq; paints & v.u'nlshe*;
flnlsli renovors; dry
cleaning; ennilslLlcd
products; leather
decreasing; pol i^ties ;
plasticizers; plastics;
germicides
Org syn; particularly
of aJipic acid &
957.); polyvinyl chloride
& its copolyra^rs, &
methacrylatc escer poly-
mers; solv for D3I in
aerosol bombs; general
vood stains; paint £t
varnish reriovers; spot
& stain recnovers; de-
greasing of cteta'.s;
in polishes; leveling
agn in dyeing & de-
lustering silk; lube
oil additive; general solv
Org syn; catalyst solv;
oil extraction
Boiler-water treatment;
corrosion inhib in
tor; Int
1)6-155
2)364
3)591
5)560
1)6-949
1)5-155
1)6-951
1)6-953
1)6-955
1)6-957
2)365
3)591
5)560
6)621
12)
1)6-157
2)365
3)591
5)560
1)6-87
2)367
3)592
5)560
12)
Cyclonexaaone,
aomonla,
hydrogen,
catalyse
Naphthalene,
hydrogen
201
Reductive
apination
(Amination)
Hydroge nation
Air; hydrocarbons
Air: hydrogen,
naphthalene(
hydrogenaced
naphthalenes
Eniijtsj^qn JFgc.t_org:
CO - 3.0, hydro-
carbons - 2.0
Sol for oils, fats,
vaxes, resins, rbr,
etc.; substitute for
turpentine; cleaning
machinery; scain-re-
tnover; shoe creaas,
floor waxes, etc.;
cleaning fluids;
lubricants
Plasticizers; deter-
gents; syn lubri-
cants; solv; per-
fusies; flavorings;
softner for com-
pounding rbr
1)6-87
1)6-679
2)773
3)599
12)
2)379
3)600
7)1-557
-------
A-J.I
t.Wlf. A-t. (Con: iu-.i.td)
It on
No.
K9
K4::n> and
Dtacctonc alcohol
(2-Poiicar.jni!,
4 hydroxy-4-
cwthyl-)
OijCOClL^CILj^O;;
6 12^2
Chcm. AbBtr.
Ri!i:i.
-------
Sourci-s nC
Comm-.liul
Process
No.
Assoclnlril
W;istrs
Tutul
l'iWi:ct I.
Uses
Acetone
260
AUol
Ajh^: acetone,
n & nrciilcal
leather; inicnclon ^old
loaf; dyeing mixture^;
antifreeze mixtures;
oxtr.iction o£ resins &
waxes; preservative t'or
onlntal tissues; cietal-
cleaning compounds;
hydraulic compression
fluids; stripping agn
(textiles); labora-
tory reagenc; the techni-
cal grade, containing
acetone, has greater
solv power
R.- f en-no- s
1)6-007
3)600
5)560
Oinitrobenzoic
acid,
hydrogen,
catalyst
311
Reduction Air: low boiling,
organic nitrates
1)6-1017
Dichloror.itrobenzene,
iron, HGl
Reduction Water: acid
Dye int; inc for
biologically active
compounds; herbicides
1)6-69
2)107
catalyst
2)107
3)608
Tlrchloroaniline,
hxpochlorous acii
16
Dechlorination Air: ether (solv)
1)6-85
7)2-424
Chlorobeiuene,
ferric chloride,
chlorine
5A
Chlorination
63.4 Solv for org otrl & for 1)6-57
(139.7)- oxides of nonferrous metals; 2)165
1972 fumigant & insec; degroas- 5)560
ing hides & wool; netal
30.0 polishes, ind odor control; 2)155
(66.0- germicide space odorant; 3)18;624
1973 mfr of 2,5-dicnloro- 9)22
aniline; dyes; int; phartn;
agriculture (fumigating
soil)
Emission factors:
benzene - 22.6,
chlorobenzenc - 1.3
p-dichlorobcnzene - 0.05
o-
-------
It.-n
N'P.
134
DP
135
136
137
138
.A- r.
TAIllK A-l. (Cjntimu-J)
t\>ri|>ounj Cliun. Alistr.
Nuiur. nntl Si'nislrv No. Or.-ll Tuxlcltv, 1V:;(i- ll.'iznnl K.illm;
Ko ruui In (WI-S) '-"'.U' "»''k^ Ai-uli' Cltr»: 2500
Diclilorodi niuromeUuuic 00007571S L)0 L)U
(Moth.ino. dichloro- S)ihl-l S)ilil-l
difluoro-)
Frcon 12
(CCljFj)
1,2-Dichloroethylene 000540590
(CIUIC)
Dichloroethyl ether 000111444 75 orl-rat L)irr-3 L)U
(Ether, bis(2-chloroethyl) (C202G (Ref 4) ihl-3 S)ins-3
ClClljCH^OOH^Ct^Cl 105 orl-rat S)ing-3 ihl-3
(C.H.C1-0) <«' 2) '|«1-3 sk"
48 2 skn abs
abs-3
(Dichloromethyl ether) 000542831 210
(C101C)
Dichlorohydrin 000096231 490 orl-rac L)irr-l L)U
(2-Propanol,l,3- (C1VC1C) ing-2 S)U
dichloro-) ' ihl-2
CI12C1CHOHCH2C1 ' S) ihl-2
(C H CT Q} ing-3
Toxlcolo-.-.v TLV
LD50: 2500 m^/kg, L'SOS air: 1V.V
ipr -r.it 75 pr»u or 450
Narcotic in USOS alr:.!VA
high concen 1000 ppm
Narcotic & irr; USOS air: IWA
produced liver 200 ppm
& kidney Injury
in experimental
animals
Irr to nuc mem USOS air: CL
of the eyes 4 15 ppm (skn)
nose; Dild or 90 Eis/nr1
narcotic; effects
kidneys & liver
in varying de-
gree
LCLo: 1000 ppm/
45M, ihl-rac
LD50: 300 ng/kg.
akn-gpg
USOS: carcinogen
Irr to ouc trera
WLo: 125 ppm/4H,
ihl-rat.
LD50: SOO mg/kg,
«kn-rbc
Crin-tno^^k
TOI.o: 142 ciK/kt-./l
TFX.'CAR, ncu-mue
TDLo: 33 ga/ks/
79 WIC, TFXrCAR,
orl-nus
known carcinogen
-------
Sources of Process
^ Cor.iiH.mul No,
ll
[ , e.\
wlorol>ciu:t no , J-»
ferric chloride,
chlorine
Carbon 159
Cclr.ichlorlJe,
SbFi, llf
_
Ethyl ether, 120
chlorine
Associated W«st o
Process W:i.ttfH Trf.irniMii
Chlorinatton
Substitution W.itor : HCl,
(Fluori nation) sodium hydroxide ,
HF
Air: chloro-
fluovohydrocarbons
Kmission factors :
Diclilorod tt'luoroc.v tliaue -
5.0, CC14 - 4.0, HCl -
3.0, KF - 3.0, trichloro-
fluorotr.0 thane - 1.0
Chlorination Air: ethyl ether,
chlorine , HCl ,
dichloroethyl
e the r
Total
I'roJiu-l ioi'.
28.5
(62.7)-
197J
222.
(4SS.8)
1973
233. S
(515)-
1974
--
Uses
507. space deodorant; 40?*
tioth control ; syn 2,5-
d ichlofo;ini I Ine ; wise
52Z aerosols, 297-
refrigerants , 91
foaui blow ing a^n
Low temp and special
purpose solv, e.g..
extraction of heat
sensitive substances
Soil f-.tr.u£ant; general
production of high-grade
scouring & cleansing;
fulling compounds; wet-
ting & penetratir^ cora-
pounds; org syn; paints.
varnishes, lacq; finish
removers; spotting &
dry cleaning; war gas
RclVr,,,.-,*
2)J65
5)3
-------
A-'J7
TAI1IJ-: A-l. (r
It on
No.
t.'.'.-no and
Kc rtr.u la
Ch«m. At'3ti.
Kotilstry No.
Oral Tux tellv,
'U<,0' '"!''-.'
Totttf Hii.i.-i.ril li.11 In
Acme Un'imlf
Toxicology
TIV
139 DlrhUiro(«!r.cancB
(IVrilaiie, 1,1-dlchloro-)
000820553
Unknown
DlcUKiropr.-pones 0013196S2
(1'ropeM, Pichlorc-) (2U1 1C YG)
CHCICCICII.
141 Dicyclohexylanlne 000101837
(Ilexylasiii.i, dicyclo-) (L6TJ A- 2H)
(C6Hu)2N!t
373 orl-r.ic
LDIo: 500,
orl-(nu3
L)irr-3 L)iir-3
11.1-3 S)U
S)ihl-3
Narcotic; degenera-
tive changes in
liver S kidneys
LCLo: 260 ppn,
Ihl-r.ic
Local ire & nervous
excitement in
experimental
anlnals
TDLo: 2400 tng/
kg/43 WC,
TFX:SEO,
BCU-OIU9
TDLo: 2400 ir.g/
kg/44 W,
TFX:CAR,
scu-mus
142 Dlechinola=ir.e
DP (Ethanol, C,2'-imiaodl-)
000111422
(Q2M2Q)
710 orl-rat
L)irr-l L)U
lng-1 S)ins-l
ihl-1 ihl-1
S)U
LD50: 2300 mg/kg,
spr-mus
LD50: 3553 mg/kg,
scu-mus
143
DP
Dtethy"lamir.e
000109897
(2M2)
540 orl-rat
649 orl-mus
L)irr-2 L)U
ing-3 S)U
S)U
.1050: 4000 Pfn/4H,
ihl-rat
LD50: 820 mg/kg,
skn-rbc
USDS air: TWA
.25 ppra or 75
144 Dlethylcne glycol
000111456
(Q202Q)
1000 orl-hmn
9000 orl^dog
3300 orl-cac
L)irr-l L)irr-l
S)ing-2 S)U
ihl-2
ID50: 2000 mg/kg,
Irn-rbt
Suspected
carcinogen
of Che
bladder
-------
Source:! Ol
Total
I'M-
22S See nmyl clilor Ule::
307
Clilorinution
See allyl chloriJc
Solv for oils, f.rc.ises,
rhr, res ins & bi-
tuminous citrl; rcn~w.il
of tar; rcclainitm: rbr;
paint & varnisli reaver
de>;rcasinj; oC notal^;
inscc; soil fumi>:aut;
rcniov.il of wax ilcp.-r.ics
on oil-veil c^ui [<:.ont
Org syn; soil
f unugancs
1)6-755
3)632
1)6-1001
2)971
3)533
Cyclohexanone,
ammonia,
hydrogen.
catalyst
Aniinatlon
Air; hydrocarbonds
Int; insec; plasticlier; 1)6-163
corrosion inliib; a:iti- 2)413
oxidancs in rbr; lubri- 3)637
catins oils, fuels; 7)2-125
catalysts tor paint, 8)130
varnishes 4 Inks; 9)130
detcrger-.es; excractant
in medicine; soaps
& detergents In
textiles & printing
Ethylene oxide,
onia
147
. Arrnnono lysis
(Amination)
Air: ammonia,
various ethanol-
amine 3
50.4 Liquid detergents for
(111)- emulsion paints, cutting
1974 oils, shampoos, cleaners,
48.3 & polishers; textile
(105.2)- specialties; absorbent
1973 for acid gases; chein
int for resins 6
plasticizers, etc.;
solubiliiing 2,4-D
1)6-467
2)517
3)640
6)622
«1 chloride, 109 Antnation Air: atraonia,
nia " ethylchlaride, KC1,
ethylamines
Water: organic &
inorganic annonia
salts & above
Emission factors:
hydrocarbons - 2.0,
NH3 - 2.0
Ethylene oxide 136 Hydratlon Air (t Kater: ethylene
glycol, ethylene oxide
5 rbr chen; textile 1)6-345
(111!)- specialties; selective 2)415
1972 solv; dyes; flotation 3)641
agna; resins; pecticides; 5)560
polymerization iuhib; 7)2-123
pharn; petroleum chem; 12)
electroplating;
corrosion inhib
122.0
(268.7)-
1973
140.5
(309.1)-
1974
Mfg: 30Z polyurethane S
unsaturated polyester re-
sins, 13Z triethylene gly
glycol, 12X textile soft-
ener, 7* petroleun solv
extractions, 7% dehydra-
tion of natural gas, 11
plasticizers S surfac-
tants, solv for nitro-
cellulose, & many dyes
& oils; husectanc for
tobacco, casein, syn
sponges, paper products;
cork conposltions; book-
binding adheslves;
dyeing assistant; cos-
netfcs: lubricants;
brake fluids; printing
Inks; lou-pressure
laminates
1)6-437
2)423
3)644
6)623
7)8-553
12)
13)33
-------
A-J'J
YAlilJi A-1. ((\>iatiiu«d)
It
No.
Clii-m. At'Str.
Registry !!o,
(WIN)
Ornl Tuxlrlty.
LUb0. nif./ks
Ti'xK: Ii.i7«nl R.-ltlii
TLV
145 Dlcchylcne glycol -Hbutyl OOOUJ7.V2
ether " ('.02C':!0-',)
(Echer, bis(2-butoxycthyl)
3900 orl-raC
llnknouu
145 Dlcchylene glycol Jlethyl 00011:367
ether (2020202)
1850
Vnknou-n
147 Dlechylene glycol JiEethyl 000111966
ether (1020201)
(Ether,
148 Diethylcne glycol
monjbutyl ether
(Ettunol, '(2-butoxy-
ethaxy)
000112345
(Q20204)
2000 orl-gpg
LD50: 850 rag/kg,
Ipr-mua
149 Diethylene glycol .
oonobutyl ether acetate
(Ethanol. :-(2-but»y-
ethoxy)-acsl:ace)
150
(C10H20°4>
Diethylene glycol
mono t thy I ether
(Ethanol, 2(2-ethoxy-
ethoxy)
153. Diethylene glycol 025961891
monoliexyl ether ncetace (202C60V1)
. (Ethanol, 2 r2-(jZ-(lnyyloxy)
ethoxy ethoxy)
4920 orl-rat
LD50: 150 mg/kg,
skn-rbt
-------
A-'.O
Sources of
Compound
Process
No.
PrcvoSii
WnM e:i
Wtiste
ri'ii en-en C
To I a I
Product ton
Uses
B-, di-. or
trietliylfne glycol
moirooclier,
stxUun sin:,
nlkyl chloride
139
139
Alkoxylut tun
Water; N:iCl, alkyl
chlorlJcu, other
S*e dictl-.ylene
glycol dibucyl
echer
High-boiling, inert 1)6-451
solv wich np;^Ucaclon 2)521
in extraction pro- 3)645
cesses & In coatings
& inks; dlluenc in
vinyl clilorU'c disper-
sions; excratcanc for
uranium ores
Solv for nttrocellu- 2)522
lose; res ins, lacq; 3)046
hi»;h-boilitijj; medium &
solv for org syn.
139
S«e dleChylcae
glycol dibutyl
ether
Sol; anhydrous reac-
tion r.edia for ors
metallic syn
Ethylene oxide,
alcohols
133
Alkoxylacion
Vatcr: cchylene oxide,
echylene, Iiigher
polyglycols, alcohols,
glycol nonoethers
11.5 Mfg: Acetate ester for solv 1)6-447
(25.3)- use; coalescing agnt latex 2)513
1973 paint; solv for nitrocel- 3)792
luose, oils, dyes, gucs, 6)636
soaps, polycers; pl&stici- 13)34
zee Int
Mono- or diethylete
glycol monoether,
acetic acid
140
Esterification
Solv for oils, resins,
gums, also for cellulose
nitrate i polyceric
coatings; plasclci:er3
in lacq 4 coatings
1)6-453
2)513
133
See diethylene
glycol mono-
butyl ether
12.6 Brake fluid diluent; coat- 1)6-447
(27.8)- ings solv; textile print- 2)515
1973 ing & dying solv; ccs- 6)636
metics & toiletries solv; 12)34
solv for dyes, nitre-
cellulose, & resins; ncn-
aqueous stains for vood;
for setting the tvist &
conditioning yarns & cloth;
textile soaps; org syn
140
See diethylene
glycol mono-
butyl ether
acetate
Solv for cellulose 1)6-453
esters, gums, resins; 2)516
coatings & lacq;
printing inks
133
See Diethylene
glycol mono-
butyl ether
1)6-447
2)517
-------
A-/.1
TAI1I.K A-I. (Continue-.!)
Item
No,
i*
155
156
157
158
159
DP
160
DP
161
162
163
Cor.pcund
H.we and
Formula
Dlcthylcno ,2
Dlecltylcne $lycol
tnon^.ietliyl other a-recnte
(Eth.inol, I(2-oeChjxy-
cthjsy)-nc«-ate)
Diethyl su'.fate
(SuUuric ioid.
diethyl cs;er)
(C,K,),SO.
2 52 4
(C H OS)
4 10 4
Difluoroethane
(Ethane, di£luoro-)
F2C2H4
DiisobuCyle-a
(Pencene, 2,4,4-
trlnechyl-)
(C8H16)
Dikstene
(2-Oxetanor.e,
4-cethylena)
DiEethylatnine
(CH_)-NH
^
(C«H_N)
1 1
N.K-Diaeth'/Unilir.e
(Aniline, direchyl)
. .
8 11
Diinechyl e:her
(Methyl et'r.er)
CILOCH.
* *
(C2H60)
N.N'-DlnxsChylformAEide
(Fortnamlde, N,H-di-
inethyl)
(CH ) HCHO
(C H 'O>
37
Chcm. Ahsrr.
Ro-Ktstry No, Or.-il Tiixlcltv, To>:ic )l:izt
(Km '"''iO' r-w/'-'' A.-nti>
OOOH1773 . 4^0 orl-i!|ij L)irr-l
(Q20-01) S)tnj;-3
ilil-1
000629139 3460 orl-gps l.)irr-l
(U'0:020l) S)hi3-3
lhl-1
000064675 647 orl-aus L)irr-3
(20SU02) 830 orl-rat 5)ins-3
LDLo: 750 ihl-3
orl-rac
026497233 L)irr-l
(DfF) S)ihl-2
012002232 l)irr-2
(1X1YU1) S)ihl-l
lng-2
003068880 560 orl-rat L)irr-2
(T4VOY DHJ Oil) LDLo: 300 S)ing-2
orl-mus ihl-2
000124403 693 orl-rat L)irr-2
(1M1) 316 orl-mus ing -2
240 orl-rbc lhl-2
240 orl-gpg S)irr-2
ihl-2
000121697 LDlo: 50 orl-hmn L)0
(INltR) ' . S)ing-3
lhl-3
okn
abs-3
000115105 ' L)irr-l
(101) S) ihl-2
skn
abs-2
000068122 4200 orl-rat L)irr-2
(VILNl&l) 1122 orl-O'js S)ing-2
(Re£ 4) ihl-2
3750 orl-mus skn
(R*£ 2) abs-2
inl K.tt In;-
ChriM-.li-
L)U
S) 1 U;', -3
lh!-2
L)U
ihl-2
L)ll
S)U
L)'J
S)U
L)U
S)ihl-l
L)U
S)U
L)U
S)U
S)ir:g-3
ihl-3
skn
abs-3
L)0
S)U
L)irr-2
S)ing-2
ihl-2
akn
abs-2
ToxK-oloi-.y TLV Cure!
-- *.
LCLo: 250 i>ptn/ilt, -- TDLo: 1
ihl-rac 81WI,
LD50: 350 ng/kg, TFX:C,\i
scu-rac TDI^>: i
LD50: 340 ng/kg, 49WI,
ivn-rat ' TFX:NEt
TDLo: 85 ng/kg/ TDLo: '.
(15D Freg), TFXiCAI
TFX:TER, ivn-rac
irr to lungs;
narcotic in high
concern
irr & narcotic in
high concern; liver
& kidney damage
in experimental
animals
. USOS air: TWA
10 ppn or 18
nc/n^
LD50: 1770 ng/kg, USOS air: TWA
skn-rbc 5 ppra (skn)
CMS depressant or 25 =g/n3
(skn)
TCLo: 200 pptn, USOS air: TWA
TFX:Ci:3, ihl-hrcn 10 ppm (skn)
Highly irritating; or 30 =3/o3
prolonged ihl (akn)
produced 1 Iver
dnniage in cxperi-
r.cntal anliruils
1D50: 1260 n>K/kg,
ipr-rac
LD50: 3500 og/V.g,
L050: 2350 mp./V.Kl
ivn-rac
-------
Sources oi
Troccss
Tola!
13S See iliutltyliMW
glvcul c\>no-
butyl ether
6.2
(13.7)-
1V73
Solv; brake fluid
cuui|KnuMit; InC
1)6-447
2)518
3)914
6)636
Soc dicChylene
glycol IT.OHO-
butyl ether
Solv
1)6-447
2)518
3)914
EChanoI,
suIfuric acid
115
Esturlf icaeion
(SulCitron)
W.iter :iml Mr: eChanol,
suliuvic acid,
dictliyl suli^ffi,
monoechyl ^ulface
EthyLating ago in
org sya
1)6-365
2)1097
3)654
4)361
8)293
Acetylene,
HF
168
Hydrofluorination Air: acetylene,
(Tluoriration) dif luoroechane
32Z Aerosol; 29Z 1)6-545
refrigerant; 9Z foam 3)655
blowing agent 13)34
Isobutylene,
V°4
70
Polymerization
Water: sodiuu hydroxide,
sodiuQ sulfate,
butyl alcohol
Alkylation; int; 1)6-227
antioxidants; surfactants; 2)S42
lube additives; plastici- 3)663
zers;'rbr chem
2468
Pyrolysis
See ketene
Aniline,
methanol
Kuthanol,
sulfonic acid
Hcthyl forrjte,
dircthylariine
26 Alkylation Water: aniline
183
191
Condensation
(dehydration)
Acylation
Air: neth/1 formate,
d inie c hy lam inc
Production of aceto- 1)6-821
arylamides; pignents & 2)829
toners; pesticides; food 3)667
preservatives; pharm
int
55.2 237. Kfr diraethylforramide 2)440
(121.5)- i dir.ethylacetasu.de, about 3)570
1973 TZ. lauryl dice thy looine 5)560
oxide (surfactant), about 9)200
17, rub chenicals (ar.tiox- 13)34
idants, accelerators);
dyes; about 23X acid gas
absorbent; solv; flota-
tion agn; gasoline
stabilizers; phar^; textile
cherc; electroplating; de-
halriag agn; aissile fuels;
rocket propellants
7.1 Solv; activator for 1)6-109
(15.7)- polyesters; alkylating 2)107
1973 agn; dye int; 3)571
stabilizer (acid 5)560
acceptor) 7)2-420
9)23
. Refrigerant; solv; 1)6-637
extraction agn; propel- 3)677
lant for sprays; chem
(reaction medium); cata-
lyst & stabilizer in
polymerization
Solv for vinyl rbsins 1)6-643
& acetylene, butadiene, 2)564
acid g.ises; catalyst 3)673
In carboxylation reac- 4)376
Clons; org syn 5)560
-------
TAB I* A-l. ((\miliim.-J)
I ton
N...
Df
165
166
167G
167
168
169
170
G
Compound '
Itae nnrt
. r'crmiln
Dimethyl sulC.ite
(Sulftiric jo 1.1,
dimethyl oscer)
(CII ) SO
32 4
(c^t^o^s)
DlMthyl sulfide
(Methyl suliide)
(C2H6S)
Dicethyl sulfoxide
(Methyl sulfoxide)
(ChyjSO
(C2H6OS)
Dinitrobenrene
Benzene, m-dinicro
Benzene, p-dinicro
Benzene, o-dinitro
cftTo
Dinitrobenzoic acid
(NO_),C K CO H
Chcm. Ahstr.
Rcr.li-uy No. Oral Toxlc.lcy. Tr-xlc I'.isaril Rnrliu;
(WUO l-'NO' III^'K!> M-tiU- CtironLe ToxU-olop.y TLV CnrclnoKCn^^^
000077731 44P orl-rat L)irr-3 I.)irr-3 Intense Irr to skn VSOS air: WA ICLo: 17 PR/^^^
(lOS-'Ol) 111! -3 lhl-3 & MUV ='.on; frc>|u<:nC 1 |'|x-n (skn) 18MI,
S)tng-3 S)lns-3 I Ivor vS kidney or 5 mg/n3 TFX:CAR, lhl-r.it
llil-3 ihl-3 d:raai;c; death rjy TUl.o: 50 mR/kg,
skn skn hu delayed for TFX:NEO, scu-rat
obs-3 abs-3 scvtr.il weeks
LCI.o: 32 ppn/411.
Ihl-rat
LU50: 100 og/kg.
scu-r jt
1.030: 100 mg/kg.
Ivn-rat
LCLo: 75 ppro/17M,
ihl-mus
Tm.o: :0 DS/kg/
(15D preg),
TKX:TEK, ivn-rat
000075133 535 orl-rat -- -- Unknown
(1S1) 3700 orl-oms
000067635 20 orl-rat L)irr-2 L)irr-l Freely penetrates
lhl-1 S)inj-l causes nausea, " .
S)lng-2 skn. chJ.lls, cramps,
skn abs-2 lithargy
abs-2 LD50: 2500
ivn-dog
TBLo: 5 g3i/kg/
(6-12D preg),
IF>::TES, orl-rac
TDLo: 8 gn/kg/
(6-12D preg) ,
TTX:TER, Ipr-rat
TDLo: 50 mg/kg/
(8D preg) ,
TFX-.TER, ivn-ham
L)U L)U Pathological
ihl-3 ihl-3 jaundice; enlarged
skn skn liver or yellow
abs-3 aba-3 atrophy, kidney
degeneration;
CNS injury
000099650 42 or.l-bdu -- .. USOS air: WA
("NR CSV) I og/mJ (skn)
000100254 LDLo: 29 orl-cat VSOA air: TWA
(WNR DNW) 1 og/m3
025550554
(OUR BNO)
015147645
(WN'R XVQ XNH)
Benzole acid, 2,3-dtnitro 000510300
(H^Tl BVQ FMW)
Bcntolc ncid, 2,4-dlnlcro 000610286
(WNR BVq EtiW)
Bentolc acid, 2,5-dinltro 000603123
(W5iP. BVQ UW)
Benzole acid, 2,6-dlnlcro 000528450
(WNR BVQ CNW)
Benzole acid, 3,4-dinlcro
' (WJIR CVQ F!W)
171 3,5-dlntro-ben:oic acid OOQ0903'.3
(Bcnrolc acid, 3,5-dinttro-) (WNR CVQ n
-------
A-',/i
Sources of
Process
Pro.-
W« s 1c
Tft'.i t nv
Total
I'rodncl
R t'fcrcncoti
lunol ,
sulfiirtc ncicl
187 Estcririition
(Sulfatloii)
Atr; SOX
Water: sodium hydroxide
Mo thy latins a^n for
aaines &. gjlicnjls
D6-6J5
2)1097
5)560
Methyl chloride,
potassium or
sodium suicide
Dirathy!sulfide,
nitrogen dioxide
151 Substitutio
152 Oxidation
22
llitration
c acid,
nitric acid
Water; potassium or
sodium chloride and
sulfide
Air; S0>, dircethyl-
sulfide"
Air; C02, 02, N2,
i 3/1 nitrogen oxides
Air; NOX (0.1
product)
Kater: sulfuric acid,
nitric acid, nono-,
i dinitrobenzene
Cas odorant; solv 1)6-487
for many inorganic 2)744
substances; catalyst 3)934
inpregnator; syn 7)9-354
flavor
Solv for poly^criza- 1)6-489
tion & cyanice reactions; 2)744
analytical regent; spin- 3)585
ning polyacrylonitrile &
other syn fibers; inJ
cleaners pesticides,
paint stripping;
hydraulic fluids;
preservation of cells at
low tenperatures; diffu-
sion of drugs, etc.,
into blood strean by
topical application;
medicine; plant patho-
logy & nutrition
Org syn; dyes; camphor 1)6-101
substitute ir. celluloid 2)166
production 3)688
5)550
5)560
Dinitrotoluene,
chromic acid
or potassium
permanganate
329
Oxidation.
Uater: chromium or
potassium salts
1)6-1051
Benzole ncld, 310 Nitration Air; S02, SOj, CO, SO,
nitric acid, . K02, CO2
ic aciil Wnti-r: nitrates, acids
1)6-1015
-------
A -4 5
TAliU; A-l. (i.miliiui-.l)
Compound
It Lin Nit^i; nm)
So, Formula,
Clicm. Al'rf
(WIN)
Ornl Toy.Ujtty, T.'xlc l-.ig.iril K.UtiU-
>Q' "'r''''!' Acute Clirt'-.it^
Toxlcolo.;v
TLV
Cnvclno
000110935
(QY&IOIVQ)
S)ing-2
t)U
S)lng-2
ihl-1
-------
Sources of
^rmieiu
Nitr.Klim
nllrio .icld,
sulfurie acid,
nKrosylsul Curie
acid
c Int I'll
W.tter : nttr.ued tjhtene
Air: NOX. nil rated
toluenes
Eniss it'll I'.u'CpfS :
NO., - 0.3
Tot.il
.'J7.6
U2>.t
1>)74
Or£ syn; CoLutdincs;
Jycs; c\pl-jsLvos
Rcfi-rcnci
1)6-1051
2)1140
12)
Ethyler.e glycal
Condensation
(Dehydration)
Water: sulfuric acid,
ethylene glycol,
dioxane
7.4
(16.2)-
1973
EthyUnc glycol,
formaldehyde
142
Condensation'
Water: formaldehyde,
ethylene glycol,
dioxolane
Solv for cellulosics 1)6-455
& wide ran3«2 o£ org 2)463
products; lacq; 3)694
paints; varnishes; 5)561
paint & varnish re- 9)199
movers; wetting & dis-
persing agn in tex-
tile processing, dye
baths, stain & print-
ing compositions;
cleaning & detergent
prep; cetwnts; cos-
metics; deodorants;
funigants; er.ulsions;
polishing compositions;
stabilizer £or .chlori-
nated solv; scintil-
lation counter
low-boilins solv & 1)6-457
extractant for oils, 2)465
fats, waxes, dyes, & 3)694
cellulose derivatives
Aniline,
aniline
hydrochloride
28
Condensation
(Dinerization)
15.7
(34.7)-
1973
Rbr antioxidants & 1)6-113
accelerators; stabili:- 2)467
ers for plastics & azo- 3)695
dyes; solid rocket 7)2-420
propellants; 'pesticides; 9)23
explosi%'es; dyes; pharm; 12)
anthelciinthia 6 insec
Bromobeneene,
sodium plienate
Substitution
(Ullnan reaction)
Org syn; perfutnery, 1)6-169
particularly soaps; 2)832
heat-transfer medium; 3)1014
resins for laminated 5)562
electrical insulation
Aniline,
carbon disulfide
25
Condensation
(Acylation)
Int; dyes (sulfur 1)6-107
colors, iudi£o, nethyl 2)290
indijp); vulcanization 3)1165
accelerator; syn org
pharn; flotation agn;
acid inhib
Fropylenc oxide
269
Hydration
Water: propylcne oxide,
propylcnc glycol
24.2 Principally solv unsac- 1)6-893
(53.3)- urated polyester resins; 2)969
1973 solv for nttroccllulofte; 3)701
shellJc; partial solv 9)204
for cclluloitr. ncctatc; 13)35
8olv ntxfjres; Incq;
coatings; prlnilnR Inks
-------
I torn
K.'.
Nll'-Tlt.' JUtJ
Formula
A-',7
TAULK A-l. (O
CliiMti. Al'tilr.
KcKl>:rv No.
TLV
1W DottVcene
(Properns, polymers,
tetraraer)
-------
A-AH
Sources of Process
Ccnntpun (1 No . Prov » * s
^^A*lonc 249 rjlvmcrli.Ulon
ASiiociali'il Vf:itfi»t
UJINI t'M Tiviilmi-n:
AJj;: prapylctic,
other olc f in.-*
Total
Pi-Oiliu-rion HiH'S
Principally syn
f u=ic s ; c-.o d J c t uc
dyes; re 6 Ins
dodecyl-
; oils;
l)o-329
3)709
12)
propylcuc - 10. 0
Inc
Phenol,
dodeccnc
295B
Alkylatien
Varer: phenol,
dodecylphenol
Solv; int for surface-
active ajn, oil ad-
ditives; resi:is;
fungicides; bjcteri-
cides; dyes; rharci,
adheslves; rbr chens;
household 6 inl
nonionic detergents
3)710
7)1-909
DichlorohyJrin,
calciuzt or
sodium hydroxide
274
Dshydrochlorina- Air; chlorine
tion
(1.0
HC1 (0.5 kg/Ms),
allyl chloriJe
epichlorohydrin (1.5
kg/Ms),
trichloropropane (0.5
kg/Hg)
Emission factors :
AHyl chloride - 4.0
229 "' Syn: about 32" glycerine, 1)6-905
(503)- about 12Z cposy 4 phinoxy 2)959
1973 resins; afg epichlorchydrin 3)717
225 elastomers; solv for eel- 5)551
(495)- lulose esters & ethers; 7)10-17
1974 high wet-strer.jth resios 12)
for paper ind; search 13)35
codlfier
Ethylene,
hydrogen,
sodiua hydroxide
210
110
See butane
Hydration
211
147
See acetic acid
See diethanol-
aaine
Water: (15-30) icg/COD/Hg.
Air: 1.1 kg/Kg cthanol,
trace acetalclehyde, ether
& ethylene
Emission factors:
1.1 kg/Kg cthanol, trace
acetaldehyde, ether &
ethylene
Enlssion factors!
echylene oxide - 10.0
362.6
(1900)-
1974
890
(1951.8)-
1973
Commercial fuel;
refrigeraat; chen
nfg
Solv for resir.s, fats.
oils, fatty a:ids, hydro-
carbons, alkali hydroxi-
des; extractive c-.edi'^:;
tafg of inc, org deri-
vatives (especially ace-
taldehyde), dyes, syn
drugs, elastorxjrs,
detergents, clear.ing
solutions, surface
coatings, cos-etics,
pham, explosives,
anti-frceze; beverages;
antisepsis; nedicine
1)5-717
3)721
7)8-305
1)5-719
1)6-347
2)527
3)725
5)551
6)523
8)162
12)
Ul
(310)-
1973
139
(305)-
1974
37Z detergents; 22Z ;as
conditioning i pctroleua
use; 5£ syn carpholice;
201 exports; 15Z else
incl polishes >j herbicides
1)6-467
2)511
3)943
5)551
12)
13)35
Ethanol,
acetic acid,
sulfuric acid
211
92
See acetic acid
Esterificatton
Emission factors:
cthanol - 5.0, ethyl
acetate - 5.0
UnCor: aulfuric acid
100.5
(221.5)-
1973
89.1
(196)-
1974
70S solv in coatings;
10Z solv in plastics;
17Z solv In lacn,
thlnners & dyes; org
syn; pharm; flavor
Smokeless powders
1)6-719
2)20
3)724
12)
13)35
1)4-297
6)023
7)8-378
-------
A-A'I
TAI11.I-: A-l. (i-.ml.lini.-J)
It on
K.i.
i on
1 ?U
Cttn pound
N.yi:o nnd
Ki- trail n
(Acetoacetic acid.
ethyl ester)
Client. Al>str,
Rc|;l»:i-v No.
O.LN)
(20V1VI)
Oinl To:.li;llv.
i-'Sr, ''*.<
3980 orl -i':it
TuxU-._l.;.i.-iirJ K.i tiny.
Aciii.> Clirtnilc ToxUvlurv
-,
S)intt-2 S)U
lhl-2
1LV G.irrlnoiter
' ' ' i ii i i . . i . ,»^O±/
191
192
DP
Ethyl acry'.atc
(Acrylic acid,
et.hyl ester)
ciL,a;cooc2:-.5
(c;H8o2)
Ethylanine
(Ethnnamir.e)
(CjHjN)
0001-OSS5 830 orl-rat
(20V1U1) LDLo: 420
orl-rbt
000075047 400 orl-rat
(7.2)
L)irr-3 L)U
S)ins-3 S)U
ihl-3
skn
abs-3
L)irr-3 L)U
S)ing-3 S)U
ihl-3
Oral aJoinistra-
tion can result
in. dc.tth; severe
local irritation
oC the fil tract;
toxic Je^cncrat tve
changes of cardiac.
hepatic, renal, i
splenic tissues;
no evidence of
cumulative effects
LCLo: 2000 p?3/4H,
ihl -rat
LCLo: 1204 ppa/7H.
llil-rbt
LD50: 1950 ing/lsg.
skn-rbt
LCLo: 1204 ppa/7H,
ihl -EPS
LCLo: 30QO ppra/4H,
il.l-rat
LD50: 390 ir.g/kg,
skn-rbc
USOS air: TWA
25 ppir. (skn) or
100 nji/n.3
USOS air: TWA
10 ppn or
18 t.g/=3
193
194
195
Ethylbenzere
(Benzene, ethyl)
0001C0414
(2R)
3500 orl-rat
Ethyl broaide
(Ethane, bromo-)
Ethylcellulose
(Cellulose, ethyl ether)
-------
A-iO
Sources of
^^^ Compound
n^l acetate.
eodiuni.
sul Curie acid
Acrylic acid,
ethanol
Process A"Rucl;itoJ W.-istc
No. Process U'.-istvrf Vn-.il cu-nt
97 Clarsen reaction Water: organic &
inorganic iicxlium salts,
ethyl acetate, ethyl
acctoccctutc
,
112 Esterification Water: polymers (11.9
kg/Ms). hyJroquinon*
(13.75 kg/Ms)
Air: cCliauul (2.65
kg/Ms), c thy Uicry late
(1.6 k£/My), "thvl-
acetate (5.2: k>;/Mg) ,
sodium carbotvi te
(0.26 ky,Av!s)
Totol
I'roJiii'i Ion
125.1
(275.5)-
1973
139.6
(307.2)-
1974
Org syn; nntipyrlne;
lacq; Jo|-vs; plastics;
tofr of dyes, i4»arm,
antiaularials,
vicanin E; flavoring
Mfg: about 3-^ emulsion
polymers (about half used
in surface costings).
about 10r. used in other
polyr.ers (csp solv coat-
ings & fibers); org syn;
misc
Kot'iTonccs
1)6-315
2)23
3)72-',
1) 6-355
2)44
3)725
6)6M
11)37
13)36
109
See Diethyl-
Benzene,
echylene
349
Alkylatlon
See xyleces
Emlssloa factors;
ethyl chloride - 1.0,
NH - 1.0
Vater: benzer.e, HC1, Heavy ars^a-
alu^iinura salts, echyl- tics disposed
benzene, tars, polycers o: by incinera-
tion
25.2'
(55.5)-
1972
2530
(5688)-
1973
2750
(6050)-
1974
2145
(4720)-
1975
Dye int; solv
extraction; petroleum
refining; stabilizer
for rbr latex;
determents; org syn;
plasticiiers;
deflocculants;
textile finishes
95. ST. let In production
of styrer-e; 2" solv;
export
1)6-345
2)505
3)726
4)431
5)561
7)2-122
12)
1)6-41
2)167
3)727
5)561
11)35
1)6-1109
Ethylene,
hydrogen bromide
72
Hydrobronina-
tion
(Brominat ion)
Org syn; nedicine 1)6-245
(anesthetic); 2)506
refrigerant; solv; 3)728
grain 4 fruit 5)561
fumigant
Cellulose,
SOT. NaOH soln.,
ethyl chloride,
HC1, benzene
or toluene
103
Alicylation
Air: ethyl chloride,
ethanol, ethyl ether,
benzene or toluene
Water: NaOH,
ethyl cellulose,
tlaCl, degraded
cellulose, all of
above under air
2.9
(6.5)-
1973
Protective surface coat-
ings; hot-r,elt adhcsives
& coatings for cables,
paper, textiles, etc.;
extrusion wire insula-
tion; pigr.ent-Erind-
ing base; toughening
agn for plastics;
printing inks; molding
powders; proximity
fuses; vitamin prepara-
tion; casing for rocket
propeliants; food &
feed additive
1)6-341
3)730
7)4-641
-------
1««
Compound
Niiac find
196 Ethyl chloride
DF (Ethane , chloro-)
CltjC^Cl
C2M5cI
Clu'ii. Abntr.
Ri-Rlsirv No.
(VIS)
000075003
-'!'./l.s Acute iMirii.-.it:
L)irr-l I.)U
S)lns-2 K)U
lhl-2
TCI.u: l.l.OOO PITH,
tFX:CXS, llil-lon
Irr to eyes; c.uiaes
least ct>xtc of ull
chl.or iiuU'ed hydro-
TLV - Cnrclnoi-.cn
USOS air: TWA
1 ,000 ppm or
2,600 rs/ra3
Ethyl chlorjacctate
(AciCic acid, chloro-
cthyl ester)
197
193 Ethyl cyanoacetate
DP (Acetic acid, cyana-
ethyl ester)
CNC^CO^K.
000105395
-------
Source* of Process
Compound No,
«cne, 106
go a chloride
Chloroacetic 100
acU, ethar.ol
Ethyl chloroacetate, 103
sodiua cyanide
Associated Vaste
PriK-oss Wustc* Ttviitment
KvdrocliU'triiuClon W;itcr A n 1 r : ethylene.
(Chloriiution) 11CI, ethyl chloride
Ent !-:.< [on fnct.*rs ;
elliylfue dU'hlur Ide -
12.0, ethyl chloride -
5.0, nsthane - 5.0,
ethane - 5.0, othylche -
5i\
U
Ester] fic.itlon Hater: siilfurlc acid.
ethyl chloroacetjtc,
chlorjacetic acid,
ethanjl
Substitution
To t« 1
Production Uses
299.7 SO* Hfr tccraothyl
(660.1). lo.ud; cchylccllulosc;
1973 anesthetic; org syn.
olkylatin;; a^n;
refriscrntioii; analy-
tical reagcat; solv-
far phosphorus, sulfur.
waxes; {usec; aerosols
Solv; org syn;
ullltary pot son gas;
vat dycstuffs
-- Org syn; pharn; dyes
10,859 Mfg: kOi polyethylene. 20Z
(23,890)- ethylene oxide, 14Z ethy-
1974 lene dichloride & deriv.,
83 ethyl beccene, 62 eth-
anol, 12« disc incl:
ethylene glycols, alua-
Inun alky Is, ethyl chloride
ethylene chlorohydris.
acetaldehyde, linear
References
1)6-333
2)506
3)731
7)5-146
9)205
U)
13)36
1)6-321
3)731
1)6-327
2)16
3)732
2)534
3)734
4)434
6)626A
7)8-519
13)36
t
alcohols* trichloroethylene.
etc
Ethylene glycol,
phosgene
144
Condensation
(Addition)
NaCl, NaOH
Solv for many polymers
& resins; solv extrac-
tion; syn of pharm, .
rbr chea, textile
finishing agns
1)6-461
3)734
Echylene,
chlorine
133
Addition
Ethylene dichloride, 126
atraconia,
sodium hydroxide
Agination
(Aamonolysis)
Water; hyrochlorous
acid, chlorine,
NaOH, HCl, NaCl,
ethylene chlorohydrin
Air: airaonia,
ethylenedianine,
higher amines,
ethylene dichloride
Water I sodium
hydroxide, airunonium
chloride
Emission factors;
ethylene dichloride -
1.0, hydrocarbons - 1.0,
N!! - 1.0
Solv for cellulose 1)6-425
acetate, ethylcellulose; 2)513
introduction of hydro- 3)735
ethyl group in org 4)434
syn; to activate 5)561
sprouting of dornant 7)5-309
potatoes; cifr of
ethylene oxide &
ethylene glycol; dyes
30 Mfg: 2SZ corbaiate fungi- 1)6-403
(66)- cldes, 13% chelating agn 2)507
1974 (EDTA), ST. dicethylol- 3)735
ethylene urea resins, 81 4)434
aalnocthylethaaolanize, 5)561
25X exports, 21! mlsc; 10}
solv for albcsin i fibrin; 12)
cedicine: neutralizing 13)36
oils; stabilizing rbr
latex; corrosion inhib
In antifreeze solutions;
textile lubricants; dyes;
rbr accelerators; making
ethylenediacnlno nitratu,
chlorate; dehairing skns;
polyaoide resin adhesivea
-------
A-SI
TABLE A-l. (f.MllluueJ)
lion
N.'.
203
DP
201
N:r.i<_- and
Kortmilu
Ethylciis dibr.'inlde
(Etlune, l,--dibro:uo)
ClL&rCtl Br
Z 2
C2H4Br2
Ethylene dichloride
(Ethane, 1.2-dichloro)
ClIjClClljCl
/ ti f*t
C2H4CI2
Clu'm. Ahucr.
RutlJsrry Ho. Oral JVxlclty,
0001C6W4 140 ji-l-rac
(E2U) 55 orl-rht
110 orl-gps
79 orl-ckn
LDLo: 250
arl-uius
OOOIP7062 680 orl-rat
(C2G) LDU: S45
LDLo: 600
orl-r.ius
LDLo: 2000
orl-doj
LD50: S60
orl-rbt
Toxic l'..i:-nrj R.-iti:u-.
Ai-iiii- UinviLt:
Dirr-J L)lrr-2
5)in:.;-'J S)in;;-2
ilil-3 itil-2
skn 6ku
abs-3 abs-2
L)irr-3 L)irr-2
S)inp-3 S)ini-3
ihl-3 ihl-3
skn
abs-2
To»li-oloi'.v TLV C.irclnoKtiii ^
LCL0; -iOO ppm/:il. UWS nir: 1UA
I!il -rat 20 pirn or 145
UMo : c--'i-5 p^Ki/lli, nu',/niJ
ilil-rhc CI. 30 pi»n
IJ^SO: JOO ng/ks, PK 50 ppm/5M/
skii-rb; 6il
LCLo: iOO prm/3H,
llil-i:rs
TCL<>: 4000 ppm/H, USOA air: r..'A
TFX:CNS, ihl-lron 50 p or 200
Irr to eyes & r.*.>;/mJ
upper respiratory CL 100 ppm
tracL. Narcotic. Ti; 200 ppn/5M/
Fatty Jejieneration 8!l
ot liver & kidneys
in arair.il experi-
ments. Dtftnacitis
& edcr.j in Che
lungs.
LCLo: 1000 ppn/4U,
Ihl-rat
LDLo: 600 mg/kj,
ipr-rac
IDLo: 500 mg/kg,
scu-rat
205
DP
Ethylene glycol
CHjOUCHjOH
000107211 2000 orl-cat L)Low L)irr-l Lethal dose tor 100 pen;
(Q2Q) 6610 orl-gpg S)ing-3 S)ing-2 can is 100 nl. CKS 260 ng/n3
LDLo: 1500 stimulation followed
orl-hian by depressioa. Kid-
ney damage causes
death. Very toxic
in parciculace
fora.
LDLo: 2700 ng/kg,
scu-tnus
LDLo: 1000 ngAg,
ipr-rbc
TDLo: 4gnAg
TFX:NEO, skn-cus
206 Ethylene glycol diacecate 000111557
(ivo:ovi)
4940 orl-gpg
LD50: 1070 rag/kg,
ipr-tsus
207 EChylene glycol 000112481
dlbutyl ether (40204)
(Ethane, 1,2-dibuCjxy)
3250 orl-rat
203 EChylene glycol 016484869
dicthyl ether. (201V102)
(Ethane, 1,2-diethoxy-)
209 Ethylene glycol 000629141
dimethyl ether (10201)
(Ethane, 1,2-dlciethoxy)
(CttjOCH2)2
4390 orl-rat
2440 orl-£p3
LCLo: 8000 ppn/4H
Ihl-rat
Unknown
-------
Sources of
^^^Compo'.inJ
MLe
br ' t
Echylene
1IC1
Ethylene,
chlorine
Formaldehyde,
carbon monoxide
Ethylene
glycol,
acetic acid
Process
NV. ' Pro-TosH
104 Bronilnation
122 Chlorination ami
De hydrocl'.l or 1 na-
tion
(Oxychlorinacion)
123 Chlorination
194 Condensation
and reduction
(Carbonylation
and reduction)
136 See dlethylene
glycol
137 Esterification
Asr.oci:ili:d
Wnsios
Emission f.-uTora:
ethylciiL* bivuiiktc
10.0, clhyl.'M -
5.0. Br, - 1.0
Air: vent gas
(Composition given
In table)
(0.93 Jfc/Mg EPC)
CO 4 hydrocarbon
emission Cor entire
ind given
Air: detailed list
given in Rcf I
Hater: detailed list
given in Ref 1
Water: formaldehyde.
methanol, alcohols.
acids
s
Air & Water: ethylene
glycol, acetic acid.
ethylene glycol.
mono- & diacetate
Wasto Totol
150.3
(331. D-
1973
Direct fired 4210
boiler |>lus (1292.7)-
scrubbcr 1973
control 3490.3
system (7701)-
tl-.ernal 1974
incinerator 2700
anJ scrubber (5940)-
system 1975
\
See abjve
.
1435
(3277.6)-
1973
1518 .
(3340)-
1974
1727
(3800)-
1975
,
2.8
(6.1)-
1973
Usos
Alnost 100£ u?ed as
far tejd In
gasoline-; Brain & fruit
fuuilgant; r.enoral solv;
waterproofing prep;
org syni insec; cedicino
Syn: St7. vinyl chlortJe,
37. nx-thylchloroform, JZ
trichloroctiiylsne, 37.
ethylene isiincs, 37. per-
ch lo roc t'.iy lore; 27. viny-
lldcne chloride; 3Z cou-
pling a£n in untiknoc!;
gasoline; paint, varnish
6 finish reaover; metal
dagreasinj; s»ps &
scouring compounds
11
507. Coolant & antifreeze;
nfg; 357. polyester fiber.
41 alkyd & polyester re-
sins, IZ emulsion paints;
asphalt-eoulsion palr.:s;
heat-transfer agn, in
refrigeration & electron
tubes; low-pressure iiai-
nates; brake fluids;
glycol diacetste; lov-
freezing dyna=ite; solv;
extractant lor various
purposes; solv nixtures
for cellulose esters &
ethers, especially cel-
lophane; cosir.etics (up
to 51); lacq; printing
inks; uood stains; aches-
ives; leather dyeing; tex-
tile processing; tobacco;
Ingredient of deicing
Solv for cellulose
esters & ethers;
resins; lacq; print-
ing inks; perfume
Rot erenctft*
1)6-329
2)507
3)736
5)563
6)627
9)205
12)
13)37
1)6-331
2)503
3)736
5)563
6)627
7)5-153
9)205
10)
11)33
1)6-391
1)6-655
2)536
3) 19; 737
6)627
8)164
9)203
11)36
1)6-445
2)537
3)738
9)203
140
See dlethylene
glycol monobutyl
ether acetate
fixative; nondts-
coloring plasticizer
for ethyl & benzyl
cellulose
High-boiling Inert
solv; specialized
solv & extraction
applications
1)6-453
140
140
Org syn (reaction
mediun); solv It
diluent for detergents
Solv
1)6-453
2)536
1)6-453
2)508
3)739
-------
A-V.
TAIlll: A-I. (Will lime.!)
lU'n
210
211
212
213
Ccv-ipound Chcm, Al».ttr,
Niv.-n: niul RculiiCry Mo.
Kovnula . (I.'US
Echylenu plwul nioujacocate 0005-'.-5%
CHjCOOCHjCu'.OH (Q20V1)
(C, H 0.)
x 4 S3'
Echylene Rlycol 00011U62
nonobutyl e:hcr (Q20-'.)
(Ethauol, 2-butoxy-)
C,H OCR,CILOH
(C H 0 )
x 6 14 2'
\
.
Echylene glycol 000112072
tnonobuCyl e:her acetate (402CV1)
(Ethanol, 2-bucoxy-,
acetate)
Echylene glycol 000110805
monoechyl erher (Q202)
(Echanol, 2-echoxy)
CHjOMCHjOCjU,
(C.H 0-)
v 4 10 2'
Oral ToxUUv, IVsIr i;.!/.ariln.-il cx|H.-rinx-nt»
WJU: IJ10 ng/kg,
Ipr-muS
TDLo: 195 pptn/SU, USOS air: TWA
TFXiIRS, ilil-hfflii 50 pj^n (skn)
LClo: 500 ppci/411, or 240 mc/m»
Ihl-ra:
1D30: 550 mg/ks,
J pr-rjc
LD50: 3'iO ing/kg,
ivn-rac
LC50: 700 ppn/7H,
il>l-mus
U)DO: 536 ng/kg,
Ipr-mus
LD50: 1130 mg/kg,
Ivn-Bits
LD50: 500 mg/kg.
skn-rbt
LD50: 230 mg/kg,
ivn-rbt
LD50: 230 mg/kg,
skn-gpg
UD50: 1580 ngAg,
skn-rat
Congestion 4 adema USOS air: TWA
of lungs & conges- 200 ppm (skn)
tion of kidneys In
animals. Irr to
eyes in hem.
Absorbed by skn
214 Echylene glycol 000111159
monoechyl ether acecaCe (2020V1)-
(Echanol, 2-ethoxy-,
acetate)
1910 orl-gps
L)trr-l L)U
S)ing-2 S)ing-2
skn Jhl-2
abs-2
LCLo: 4000 ppo/4H, '
ihl-rac
LCLo: 1820 ppa,
Ihl-mus
LD50: 1710 ag/kg,
ipr-ous
Absorbed by skn USOS air: TWA
LCLo: 1500 ppci/4H, 100 ppm (skn)
ihl-rac or 540 mg/m3
LD50: 1420 mgAg,
ipr-mus
215 Echylena glycol 000112254
nonohexyl echer (Q206)
(Echanol, 2(hexylaxy))
1480 orl-rac
LD50: 890 mg/kg,
skn-rbc
-------
Source! of Pfoccsn Ast.iocl.itud Waste Total
Compound N'o. Prooosi WIIBU-S Treatment Production Viet
137 S#« ethylena - Sol for nitrocellulose,
glycol d'.acctate cellulose acetate,
camphor
138 See dicthvlene Emission factors: « 62.4 Solv for nttroccllu-
glycol nenolnityl ethylcue oxide - 1.0, (137.8)- lose resins; spray L«q;
etlicr butanol - 0.5 1973 quick-drying lacq;
varnishes; enamels;
dry-cleaning cora-
pounds; varnish re-
movers; textile
(preventing spotting
in printing or dye t IK);
mutual sol for "soluble"
mineral oils to hold
soap in solution & to
improve the emulsifying
properties; syn 2-but-
oxycthyl acetate, dl(2-
bu toxye thy I ) phtha la te
1)6-445
2)537
3)739
1)6-447
2)512
3)446
5)560
9)204
12) ..
13)37
High-boiling solv for
nitrocellulose lacq,
epoxy resins, multicolor
lacq; film coalescing
aid for polyvlnyl acecata
latex
2)512
138
See dlethylene
glycol nunobucyl
ether
Enission factors;
ethylene oxide -
1.0
72.2 Syn: 2-echoxyechyl acetate 1)6-447
(159.0)- solv; nitrocellulose,. nat- 2)316
1974 ural & syn resins; cutual 3)527
86.5 solv for farculacion of 6)636
(190.3)- soluble oils; lacq & lacq 9)204
1973 thinners; dyeing & prtnc- 10)
ing textiles; varnish re- 12)
movers; cleaning solutions;
leather; anti-icing addi-
tive for aviation fuels
Emission factors:
ethoxyethanol - 1.0
Solv for nitrocellu- 2)516
lose; oils & resins; re- 3)526
tards "blushing" In lacq; 5)561
varnish removers; vood 12)
stains; textiles;
leather
138
.See Diethylene
glycol monobutyl
ether
High-boiling solv
1)6-447
2)517
138
Emission factors:
2-meChoxyethanol -
1.0, ethylene - 1.0
39.1 SIS Jet fuel deicing 1)6-447
(86.2)- additive; 107. solv far 2)518
1973 nitrocellulose, cellulose 3)740
acetate, natural & syn 5)561
resins, alcohol-soluble 6)636
dyes, varnishes; leather; 9)204
perfume fixative; wood 12)
stains; sealing moisture- 13)37
prooC cellophane
-------
A -5 7
TAU1.K A-1. (I
It
Chum. Al>»tr.
Kcj'.istry No.
(WIN)
Oral Tuxlc.Uy. T.'xlc i:.i;-.»rd
Ll'',n. I'ly.As "TTuTr TiTr
TIV
217 Ethylrne s'.ycol OOOUlV.96
monojicthyl cllicr ucetute (1VO-01)
(Eth.mol, r-owdioxy-
ncecarc)
3390 orl-rac
1250 url-siv,
If.lo: 7iX)0
Jlil -rat
-ill, VSOi nlr: TWA
25 r,« (skn)
or 110 r.s/rij
21S
219
Ethylcne
nonoocCyl ccher
(Echanol, 2-oclyloxy-)
Unknown
Ethylene glycol
monophenyl ether
(Ethanol, 2-plienoxy-)
(Q20S)
000122995
(Q20R)
1260 orl-rit
220 Ethylene glycol 0028C7309
moospropyl ether (Q203)
CEthanol, 2-propoxv)
A890 orl-rit
LCLo: 2000 ppoi/4H,
ihl-rac
LD50: 940 mg/kg,
skn-rbc
221
OP
Echrlonc oxide
(CH,)20
C2H4°
222 Ethyl ether
(Ethane, l,l'-oxybis)
000075218
(T30TJ)
000060297
(202)
330 orl-rac
270 orl-gpg
1700 orl-rbc
L)irr-3 L)irr-2
S)lhl-2 S)U
L)irr-2 L)U
S)ihl-2 S)ihl-2
akn
abs-2
Irr to eyes & nuc
nea of respira-
tory tract;
pulmonary edeoa
LC50: 1462 ppe/4H,
ihl-rat
LC50: S35 pptn/AH,
ihl-ous
LC50: 960 ppra/4H,
ihl-dog
LCLo: 7000 ppn/150M(.
TDLo: 30 og/a3
IFXiMUT, ihl-nan
CNS depressant;
death results
from severe &
continued expos-
ure
LDLo: 2000 rag/kg,
ipr-rat
I'SOS air: TWA
400 ppni or
1200 mg/rP
223 2-Ethylhexanol
(l-Eexanol,-2-ethyl)
-------
A-si;
Source* of
Ct'mpo-.nul
Process
No.
Associated
Wnttl ea
Tumi
1'rodm-i Ion
Solv for nitrocellu-
lose, cellulose acetate,
various £unis, resins,
waxes, oils; textile
printing; photo film;
lacq; Jopes
2)518
3)7'>0
5)561
13$
See dlethylcne
glycol monobutyl
ether
Solv for cellulose
esters; plasticizer
1)6-447
3)740
13*
138
Solv for cellulose
acetate, dyes inks, re-
sins; perfume & soap
fixative; bacterial
agn; org syu of plascici-
zers, germicides,- per-
fume p.trl & pharm
1)6-447
2)519
1)6-447
2)519
Echylene,
oxygen,
air
135
Oxidation
Air! ethylene,
ethylene oxide
Water: flow from 2
planes given in I)
1890 Syn: ethylene glycol 1)6-431
(4167)-' 27X ar.tifreeze; 23X poly- 2)537
1973 ester fiber S. fUn; 137. 3)741
1765.2 surfactants; 107. mise; 6)623
(3888)- 9Z ethanolamlr.es; 7)8-552
1974 petroleun demulsifler; 11)37
funlgant; rocket propel-
lant; sterilizers; insec
117
See ethar.ol
process to. 110
n-BuCyraldehyde,
hydrogen
79
Condensation and
hydrogenat ion
Emission factors:
ethanol - 3.0,
ethylene - 3.5
Air; butyraldehyde
(58.5 kg/Mg)
light hydrocarbons
(U3.5 kg/Mg)
2-ethylhexanol
Emission factors:
hydrocarbons - 227.0,
butyraldehyde -
117.0
32.8 657. Ind Solv (smokeless
(72.4)- powder); 257. syn; 37.
1973 anesthetic; perfumery;
27.2 extractanc; alcohol
(60)- denacuranc
1974
Heavy ends 182.5 Mfg: 807. plasticizer,
usually (402.3)- mostly for PVC resins,
burned 1973 107. 2-echyl he.xylacrylate
defoaming agn; wetcing
agn; org syn; Solv mix-
tures for nitrocellulose,
paints, lacq, baking fin-
ishes; penetrant for
mercerizing coccon; textile
finishing compounds;
plascicizors; inks;
rbr paper; lubricants;
photo; dry cleaning
1)6-369
2)509
5)561
6)630
7)8-486
9)205
10)
12>
13)38
1)6-261
2)605
9)203
12)
13)38
Sodium
ethoxide,
methylene
chloride or
chloroforn
154
Substitution
(Addition)
Air or water;
chlorine,
chlorohydrocarbons
Int; general purpose
food additive
1)6-495
2)821
3)743
-------
TAIILL A-l. (i
Icon
KJ.
225
Compound
N.v.to mul
Ethyl oxalatfl
(Oxalic aciJ, dlet'iyl
eater)
(cooc2»5)2
-'59:i 400 orl-rat -- Toxic
(20W02)
»
TLV Cnrcli
226 Ethyl so«lli;n oxaU.-etaco 026103775
DP (Oxjlacecic a;ld, Jletliyl (20VT1VO i
ester) -NA-)
227
DP
FornalduhyJe
(IKHO)
000050000
(VH1I)
228
DP
229
DP
800 orl-rat
LDLo: 35
orl-wmn
260 orl-gps
Fonnanide
BCOSH-
(CHjNO)
Forale acid
HCOOH
(CHj02)
000075127
PVH)
000064186
(VHQ)
1210 orl-rat
1100 orl-=us
4000 orl-dog
L)irr-3 L)alr-l
alr-1 S)U
S)ing-3
lhl-3
L)irr-2 L)U
S)lng-2 S)U
lhl-2
L)lrr-2 L)irr-2
S)tng-3 S)inj-l
ihl-2
TCIo: 13.3 ppn,
TFX:IRR, ihl-hnn
Irr; violent
vomttins & dier-
rhea leading Co
collapse
LCLo: 250 ppm/4H,
Ihl-rat
LD50: 420 cig/kg,
scu-rat
LCLo: 900 tng/n /
2H, Ihl-sius
LDLo: 16ag/kg,
Ipr-mus
LD50: 300 mg/kg.
scu-mus-
LDLo: 550 mg/kg,
scu-dog
LCLo: 620 mg/m3/
8H, ihl-cat
LDLo: 240 ing/kg.
«cu-rbt
LD50: 2539 mg/kg,
iras-gpg
TDLo: 6 gm/kg/
(11-160 preg),
TFX:TER. ipr-rat
LD50: 940 ng/kg,
Ipr-rr.us
LDSO: 145 mg/kg,
Ivn-tnus
LOLo: 239 mg/kg,
ivn-rbt
USOS nir: TJ.\
3 p?ra; CL
5 ppn; PK
10 PPQ/30M/8H
Suspected
carcinogen
of the lung
TDLo: 1300 mg/kg/
65MI. TFX:NEO,
leu-rat
USOS air: TWA
20 ppm
USOS air: TWA
5 pptn or 9 tng/cr
230
Fuurlc acid
HOOCCHCIICOOH
000110178
(qviuivq-i)
L)Jrr-l L)U
S)lng-l S)U
LD50: 200 mg/kg.
ipr-mus
-------
A-l.t)
Source* oC
^^ Compound
HFlc aci.!.
eth.inol
EthyUceta:e,
ethyl oxalaee,
sodium
Me Chanel,
air.
liver
catalyse
Process Associ.-U oil Vnsru
No. Process WnHto^ Ttvutrn-nt
HI EsterlCicatlon Vntcr: solv, othauol,
oxulic acid, ccliyl
oxaLito
Air: cdianal & solv
119 Clalsen
reaction
212 See acetalde-
hyde
193 Oxidation Air: CO (63.5 g/kg
37Z fornaldehyde) .
H2 (7.6 g/kg),
CH4 (1.25 g/kg).
HCHO (trace),
CH,OH (trace)
Water! dimethyl ether
Total
Privliirllon Us*s
Solv tor culluloae
& ethers, mar.y natural
& eyn resins; radio
Cube cathode fixlnjj
lacq; dye Inc; pharro;
perfume prep; org
syn
Dyes, syn
2918 Hfg: 30S urea & melanino
(6424.1)- resins, 24Z rhenolic rc-
1973 sins, 97. acecal resins.
2654.0 67. pcncaerychricol, °7-
(S345.S)- hexaniechyler.etecrami^.e.
1974 4% melaniine-resins, 3Z
tetraliydrofuran, 37. acet-
Sea above ylcnlc chemicals, 2" -4,4'
methylenedianillne, '^Z
tritnethylolpropane, 11
acrylic escers, nisc, incl
31 chelating agns & 21.
textile applications;
dyes; cedicir.e (dis-
infectant, fungicide.
germicide} ; eabalrain;
fluids; preservative;
hardening aga;
1)6-351
2)82S
3)752
1)6-373
1)6-723
1)6-649
2)564.
3)776
- 6)632
11)36
13)38
Methyl or ethyl
190 Asmonolysls Air
Air: raethanol or
ethanol
Solv, softener. inC in
org syn; printing irk;
sodiun^ silicate gelation
1)6-641
2)364
3)776
7)10-105
211 See butyric
acid
83 Condensation
Emission factors:
CO - 15.0, formic
acid - 1.0
Air: acetaldehyde,
formaldehyde,
methanol, ethanol
Water: sodlua :
formate, inorganic
sodiun salts
24.2 Dyeing & finishing of 1)6-719
(53.1)- textiles & paper; leather 12)
1973 treatment; chem (formates,
oxalic acid, org esters); 1)6-271
nfr of fuoigancs, Ir.sec, 2)565
refrigerants; solv for 3)776
perfumes, lacq; electro- 5)561
plating; medicine; brew- 7)10-102
ing (antiseptic); silver- 9)201
ing glass; cellulose for-
mat; natural latex
coagulant; ore flota-
tion; vinyl resin
plastlcizers; animal
fee additive; packaging
Benzene, air
catalyst
Maleic acid,
catalyst
21
39
Oxidation
IsoDorization
Air or Hater:
benzene
Emission factors;
benzene - 15.0, malic
acid - 4.0, fumeric
acid - 4.0, NH.J - 3.0
Air: unrcacted
hydrocarbons
24.3 347. Food acidulants, 267. 1)6-99
(53.5>- synthetic resins (unsatd 2)569
1973 . polyesters), 14J pajer- 9)202
19.1 size resins, 107. surface 10)
(42)- coatings (aUyd resins), 12)
1974 47. plasticlzers; resin 13)38
esters & adiiucts; ujjrad-
" ing natural drying oils 1)6-145
(especially tall oil) to
improve drying character-
istics; mordant; org syn
-------
A-M
TA11IJ-: A-1. (
It t'ra
K.'.
Compound
Nnno nnJ
Korfi'.uln
231 Clyceralclchytlc
Clira. Ahitr.
R
Registry No. OrM Toxtclty, T.'slc li.mird R.u !»;
Toxicology
T!,V
000367/.75
(VIIYHIQ)
IDU: 5000
orl-ruc
232 Glycerine
Of (Clycorol)
CH2C!lCllOl(CH.,0;i
233 Glycerol Cri-
(polyoxypropylene)
ether
000056315
(QUXHQ)
31500 orl-mus
7150 orl-gpg
L)lrr-l
S)ln£-l
Jill Irr
10 r..g/n
234 Glycine
Of
000056406
(21VQ)
235 Clyoxal
OCKCHO
000107222
(VHVK)
760 orl-gpg
2000 orl-rac
LDLo: 100
orl-rac
L)lrr-2 L)U
S)ing-2 S)U
ihl-2
LD50: 200 mg/kg,
ipc-mus
-------
A-lil'
Source* of Process
^^^ Compound Ho.
fflWcln. 237
hydrogen peroxide
Allylntcohol, 235
hydrogen peroxide.
sodlura hydroxide
/
A.ir.oclateJ Wn.ile
1'rcK'e*:! Wasu*s Ttvntn».-nt
Epuxlclntiou and Watpv: acrolcm.
hydrat lot: glyuiJaUlcliyJc ,
(Hydruxyl ucion) glyecraltluhyJo
Epoxldntion and Air: allyl alcohol
hydrutioii (6 kf/Mij), butjnol
(2 kf./ms), ncroletn
(20 k.;/M>:). lisl't
Impurities (12 kg/Ms)
Water: allyl alcohol
(4kg,'M>0 , glvrtfrln
(3.5 kp/Ns;), light
Impurities (U.5 kg/Kf)
Tolal
Production
9'i.4
COB)-
1973
(Synthetic
only)
161. 8
(356.3)-
1974
tlsos
BlochenU-al r«scnreh;
Int; nuti-ltlon; prep
of polyesters, udhe-
Ives; cellulose modi-
fier; leather tannlnc.
232 dru$s & cosmetics,
217. nfg alkyJ resins, 157.
tobacco, 127. fjods & bev-
erages, HZ cellophane.
107. polyester polyolj, 5Z
explosives, niic; solv;
printer's ink, rolls;
polyurcihane polyols;
emulsifying a:;n; Inks;
binder fjr cc-ents &
mixes; paper coatings &
finishes; special soaps;
lubricant & softener;
bacteriastat; hydraulic
fluid
Rofi-ri'nces
1)6-799
2)532
1)5-793
3)790
3X9
6)633
9).! 03
10)
13)39
Clyeraldehyde,
hydrogen
Allyl alcohol,
peraeetlc acid
Epiehlorohydrin,
sodiuo hydroxide,
sodium carbonate,
toluene, HC1
23S Hydrogenatlon
sodlua hydroxide
275 Epoxidatian and
hydrolysis
(Feroxldation
and hydrolysis
300 Hydraclon and
substitution
(hydration and
dehydrochlorina-
tion)
303 Addition and
substitution
(Chlorohydrinatian
and hydrolysis)
Air: glyceraldehyde,
glycerol
Water: acetic acid
Hater: glycerol
(& toluene amounts
given in 1))
1)6-801
1)6-907
2)532
1)6-983
4)499
6)633
7)10-627
1)6-991
Clycerol,
propylene oxide,
ethylene oxide
276
Polyether
formation
Air or water: propy-
lene oxide, glycerol,
product, propylene
glycol
Mostly flexible poly- 1)6-909
urethane foaas, also 13)39
rigid foams, surfactants,
lubricants & functional
fluids
Chloroacetic acid,
amoonia
Aceuldehyde,
nitric acid
93
80
Ammonolysis
Oxidation
Water: ammonia,
ammonia salts,
chloroacetic acid,
glycine
Org syn; medicine;
biochemical research;
buffering agn; chicken
feed additive; reduces
bitter taste of saccharin
Kfg of textile resins
for percanent press
process; dimensional
stabilization of rayon,
& other fibers; insolu-
bilizin; agn for com-
pounds containing poly-
hydroxyl groups (poly-
vinyl alcohol, starch,
& cellulosic materials);
insolubiliztng or pro-
teins (casein, gelatin
& animal glue); embala-
ing fluids; leather
tanning; paper coatir.;s
vlth hydroxylethylcellu-
lose; reducing agn in
dyeing textiles
1)6-317
1)6-263
2)535
3)792
4)502
-------
A-(/3
TMIU: A-l. (i\mtlniK.t)
Compound
Knnc and
Chen. Absir.
Registry No. DIM! Toxiclty, TV-sIc li:ii;iii-J l!.u tr.i
236 CunniJlne
0001U 008
(ZY/UN)
LULo: 500
orl-rbt
237 KepCer.e
000592767
(6U1)
L)U L)irr-l
S)ing-l S)U
ihl-1
Toxicology
LDLo: 175
ipr-rat
UUo: 300 ni|;/ks.
Kcu-mus
LDLo: 200 tiig/ks.
scu-dog
U)lo: 100 msAg..
ipr-cat
LDLo: 200 rag/kg,
ecu-cat
LDLo: 500 ng/kg,
scu-rbc
LDLo: 1500 mg/kg,
Ipr-gpg
LDLo: 100 rag/kg,
scu-gpg
Simple aspliyxi.int
238 tiexachloroechar.e
ane, hexJchloro)
(C2ci6)
000067721
(GXGGXCXG)
LDLo: 325 ng/kg, USOS air: TWA
ivn-dag 1 ppn (skn)
LDLo: 4000 mgAg, or 10
scu-rbc
239 Hexaiecyl alcohol
(1-Hexadecarol)
000124298
PracCically non-
toxic
LD50: 2600 mg/kg,
skn-rbc
240 Hexasethyler.: glycol
(1,6-Hcxanediol)
000629118
(Q6Q)
3730 orl-rat
241 Hexansthylenecetramiae
000100970
(T66 E6 ABC IE
I&BN DM FN
UMTS)
L)irr-2
S)ing-2
L)irr-l
S)lng-l
ska rash
LDLo: 512 ng/kg,
ipr-mus
LD50: 9200 mg/kg,
Ivn-rat
TDLo: 144 gm/kg/
72WI, TFX:NEO,
scu-rat
i42 Hoxylene glycot
(2,4-Pentanediol,
2-metliyl)
000107415
(QY1XQ)
4760 orl-rat
(Ref 4)
3696 orl-rat
(Rcf 2)
3860 orl-mus
L)lrr-2 L)irr-l
S)tng-l S)U
lhl-1
Irr to skn, eyes
& ciujt men; large
oral dose produce
narcosis
LD50: 1299 mg/kg,
i pr-mua
25 ppn;
125
proposed
1974
-------
Sources of
Compound
Process
No.
Wast c
Tn-nlruMit
Total
Product ion
R<'ff r c tie*1
176
Atzunolysls Alt:: uiwun
204
(450)-
1967
Org syn
1)6-595
2)583
Cj refinery gas
(propylone),
C^ re finery gas
(butylenes)
Perchloroethylene,
Chlorine,
sodium hydroxide
S3
251
219
Addition Air: olcfins
(Polymerization) Emission factors;
hydrocarbons - 2.0
See Process 58
above
Chlorinacion
Water: NaCl. SaOH,
chlorinated hydro-
carbons, perchloro-
ethylene, hexachloro-
ethar.e
Org syn; plant 1)6-201
growth retardant; 3)30!.
lubricant additive; 12)
catalyst surfactants
" 1)6-337
Org syn; retarding ajn 1)6-741
In fermentation; cazo- 2)509
hor substitute in ni;ro- 5)561
cellulose;, rbr accelera- 7)5-168
tor; pyrotechnics &
smoke devices; solv;
explosives; cedicine;
high pressure lubri-
cants; noth repellant;
pesticides
45.7 Perfumery; eaulsifier;
(100.7)- emollient; faan stabilf-
1973 zer in detergent; face
creams; lotians, lip-
sticks; toilet pre;
ehen int; de:erjents;
pharm; cosxetics; base
for making sulfonated
fatty alcohols; to re-
tard evaporation of
water, vhen spread as
a film on reservoirs,
or sprayed on growing
plants
2)599
3)532
6)
Solv; resin int;
coupling agn
2)603
Formaldehyde,
amconia
196
Condensation
Air: formaldehyde,
ammonia, methanol
Water: formaldehyde,
ammonia, methanol,
hexace thyle no te tromine
Emission factors:
methanol - 5.0, NH.. -
5.0. formaldehyde - 3.0
If off-gases 45.7 527. Catalyst In phenol- 1)6-659
are incinerated, (100.7)- formaldehyde & resorcinol- 2)601
NOX will be 1973 formaldehyde resins; 407. 3)307
produced high exploslve-cyclo^.ite; 6)603
ingred in rbr-ta-tex:ile 9)199
adhesives; protein C3d- 12)
ifler; org syn; phara; 13)39
fuel tablets
Dlacetone
alcohol,
hydrogen
241 Ilydrogonatlon Atr; diacetone
alcohol,
hcxylene glycol
10.9
(23.9)-
1973
1)6-809
2)839
3)311
4)531
9)203
-------
A-65
TAP.Ii: A-l. (fonlliint.1)
Item
No,
243
244
DP.
245
246
247
248
D?
249
250
Compound
Nn;ie and
Kovrmiln
Hydra^m cy.inlde
(Hydrocyanic ocid)
11CH
(C1IN)
Hydraquinone
C,H,(OH)
64 L
Isobutyl acetate
(Acetic acid.
Isobatyl ester)
(C6HU02)3
Isobutyr.ildehyde
(en KCHCHO
. f, n\
4 '8
Chen. Ab:;I r.
Rcj4l.*trv Ho.
(WUO
000074903
(NCI!)
000123319
(QR DQ)
000123513
(Q2Y)
000107846
(C2Y)
000563462
(1Y1U1)
000072831
(Q1Y)
000110190
(U10V1)
000078842
(VUY)
Ornl Toxlcltv,
LI>50. iny/k;'.'
3700 uS/kSi
orl-mua
750 «S/kg,
or 1 -hem
LDLo: 4,
orl-Jog
LDLo: 2,
orl-cat
320 orl-rat
(Ref 4)
370 orl-rat
(Ref 2)
400 orl-mus
200 orl-dog
70 orl-cat
300 orl-pgn
500 orl-gpg
1300 orl-rat
LDLo: 4250
orl-rbt
_
...
2460 orl-rat
LDLo: 3750
orl-rbc
4760 orl-rbt
2810 orl-rat
(Ref 2)
3700 orl-rat
(Ref 4)
Toxic !-n tii ril U.iitm;
A^-utu (:l.r..i:lc
L)Irr-2 I.)U
S)ins-3 S)U
iht-3
«kn
abs-3
__
..
L)irr-2 L)U
S)ing-2 S)U
lhl-2
L)irr-2 L)U
S)ing-2 S)U
ihl-2
L)irr-3 L)U
ing-3 S)ing-l
ihl-3 ihl-1
S)ing-2
ihl-2
ska
aba -I
Toxl^olouv TLV Carcinogen
LCLo: l^O Biu/ni3/ USOS air: TWA
111, 1 hi -limn 10 ppra (skn)
Death tlirough or 11 n\s/m'
asphyxia
LCLo: 5i4 p|ira/5M,
ihl-rat
LC50: 169 ppm/jOM.
ihl-mus
LD50: :990 us/kg,
ipr-mus
LDLo: 3 cng/kg.
LD50: UOO ug/kg,
ivn-mus
LD50: :?00 iigAj,
ims.-tnus
Contact dcrnatitic
LD50: 170 ng^s, . .
ipr-rat
LDLo: ^00 mg/kg,
scu-rat
LD50: 115 mg/kg,
ivn-rat
LDLo: 100 mg/ks,
ipr-mus
LD50: 190 ng/kg,
scu-mus
LD50: 125 mg/kg,
ipr-rbt
LDLo: 150 mg/kg,
ipr-gpg
LDLo: 200 ng/kg,
scu-gpi
LDLo: 190 mg/k«,
par-frg
LDLo: 813 mg/kg, USOS air: TWA
ipr-rat 100 ppa or 360
LD50: 3970 mg/kg, ng/m3
skn-rbt
__ .« ..
V
Simple asphyxiant
LCLo: 8000 ppm/4H, USOS air: TWA
ihl-rat 100 ppm or 300
D050: 4240 mgA-.g, mg/m3
skn-rbt
LCLo: eOOO ppra/4H, USOS air: TWA
ihl-rat 150 ppro or 700
mg/m3
"
Anesthetic; irr
to eyes & roue
mem o£ the res-
piratory tract
LCLo: 5000 ppn/411.
ihl-rat
-------
A-hb
Source* of
Process
No.
VAN It;
Tmitmi'
Totnl
Production
R«!foronce.s
Kla
AnJrussow
Process
Air; ammonia, r.vMtar.
S02, HCN, CO
Vn t c r; amnonia,
pltosphacca, plu<."Hior
acid. HCN, suHurlc
acid
133.1 Mfg: nalnly ocetono cyano- 1)6-517
(104.3)- hyJrin (syn irethyl modi- 2)620
1973 acrylncc). also iidipo- 3)S16
nltrllc. cliclaetnu a.cns 5)501
(KTA, EDtA). aoJiura 7)6-583
cyanide, cyanurtc 13)39
chloride, dyes; ruinljant
for orchards & tree crops;
chelntes
Most KCN (70-9K) produced
& used capcively
p-E«nzoqui.tor.e,
Iron dust.
12
Emission factors:
hydrocarbons - 2.0,
qulnonc - 1.0
8.1
(17.9)-
1973
Photo developer (except 1)6-77
color flla); dye int; 2)622
nedicine; ancloxidant; 3)416
inhlb; stabilizer la 4)547
paints & varnishes, 7)11-469
Bator fuels & oils; 9)23
atloxidant fjr fats 12)
& oils; inhib of
polymerization
05 hydrocarbons,
aulfurlc acid,
sodium hydroxide,
hexane
230
Extraction
Water; sodium hydroxide
sodium sulfate, hexane
Photo ch:o; org syn; 2)244
phara products; cedicine; 5)561
solv; deternlaation of
fat in ailk; nlcroscopy;
flavoring
(Mixtures, usually also
containing normal acyl
chloride); solv (nitro-
cellulose, varnishes,
lacq, neoprer.e); roto-
gravure inks; soil
fumigation; org coo-
pounds
Org syn; dental & 1)6-765
surgical anesthetic; 3)913
high octana fuel nfr
Isobutyraldehyde,
hydrogen
261
Hydrogenation
Isobutyl alcohol,
acetic acid
262
Esterificatlon
Water; tnobutyl acetate,
isobutyl alcohol, acetic
acid, sulfuric acid
Air; Isobutyl acetate,
isobutyl alcohol
60.2 25X Solv - costly acetate 1)6-873
(132.8)- in paints & l»cq; 257. 2)649
1973 lube oil additive; 1CZ 3)839
Int tor amino coating 5)561
resins; substitute for 7)3-828
n-butyl alcohol, pair.t 9)203
removers; fluorooatric 13)39
determinations
S.3 Solv for nltrocellu- 1)6-875
(11.75)- loss in thinners, seal- 1)6-287
1972 ants, & topcoat lacq; 2)22
perfumery; flavoring 3)839
«gn 5)561
260
See n-Sutyr-
aldehyde
173.6 int for rbr anti-
(381.9)- oxidanta & accelcra-
19?* tors, for r.eopentyl
glycol; org syn
1)6-869
2)649
3)364^
41582
12)
-------
A-6/
TABU: A-I. (i
It I'm
ChiMii. Aimer.
KuKislry No.
(W..N)
Or.il To/.lclty, Toxic liasard I!.-;tine.
LPjiQi "'f./kj'. At'iitu Cliror.lc
ToxU-oloi;v
TLV
251 laobutyrlc acid
>2C
(01^)2010)011
000075J12
(QVY)
280 orl-rat
L)iri--2 L)irr-2
S)ln«-2 S)U
Data based oti
IjniUcJ anlnial
CX|«r intents
LD50: 500
sku-rbt
252 iKodecanolc acid
253 Isodecanol
(Is»!ecyl alcohol)
0289335!)?
(QV6Y)
025339177
(Q7V)
UnVnown
Unknown
254 IsoocCyl alcohol
001341419
(QX&MX)
1480 orl-rac
255 Isophorone 00007S591
(2-Cyclohexen-l-one, (L6V BUTJ
3,5,5-triBiethyl) C D D)
COCKCCCHj)^:.
000121915
(QVR CVQ)
2330 orl-rat
256 Isophchalic acid
DP C,H. (CO-H),
L)irr-2 L)U
S)ing-3 S)U
lhl-3
L)irr-l L)U
S)ing-l S)U
ihl-1
Kidney polsoa; USOS air: TOA
irr; lachrymator 25 ppra or 140
LDLo: 1340 ppm/4H, mg/nJ
ihl-rac
LD50: 4200 ogAg,
ipr-mus
257 Isoprene
CH2C(CH3)CHCH2
(C5Hg)
000078795
(1UY1U1)
L)irr-2 L)U Irr to nrnc men
S)ihl-2 S)U - of eyes, nose &
ing-2 upper respiratory
trace; no data on
hnn exposure
LD50: 144 ng/1
air, ihl-nus
258 Isopropyl acetate
(Acetic acid, isopropyl
ester)
259 Isopropyl alcohol
C1LCHOKCH3
000103214
(1YOV1)
000067630
(W
5800 orl-rat
6000 orl-dog
LDLo: 2371
prl-hnm
LDIOO: 5000
orl-rbt
LDLo: 192
orl-mus
L)irr-l L)U
S)ing-2 S)in2-l
ihl-2 ihl-1
L)lrr-l L)U
S)lng-2 S)ing-l
ihl-2 ihl-1
Narcotic In high
concen
ICLo: 400 ppm,
TrX:Ii«, ihl-hcn
Local-irr & in
high concen a
narcotic; absorbed
by the skn
LD50: 533 rag/kg,
ipr-mus
LDIOO: 6000 me/kg,
scu-tnus
LDLo: 1963 ng/kg,
ivn-c.it
LDSO: 16 nig/kg,
ckn-rbt
LDLo: 6 ng/kg,
scu-mas
USOS air: TWA
250 ppro or 950
USOS air: TWA
400 ppra or 300
0 pp
/nJ
-------
Sourer* of
Cpnp
-------
259
A-G'J
T.M'.li: A-l. (C
I torn
No.
Compound Chom. Ab'.'tr.
Nrrae ntid Registry Ni». Oral Ti>:r>0- 1"!-'v!'
i'. TV*lC IKI/..TK! Kalt'iv
AotltC Uiru::io
Toxioolui'.y
TI.V
C.irclno
2£0 Isopropylarr.ine
D? (CU.
000075310
(ZV)
820 orl-rnt
L)irr-3 L)lrr-2
263 Ketere
000075296
(GY)
(QR XV)
000099S93
(QR DV)
000463514
(OCU1)
1300 orl-rat
L)irr-3 L)U
S)ihl-3 S)ihl-3
ing-3
Anesthetic;
animal studies
suggest low
systemic
toxic Ity
LDLo: 250 rig/kg,
ipr-mus
Pu loo nary edema
LCLo: 23 ppra/3CM.
ihl-nus
LCLo: 53 ppm/
100M, ihl-rat
LCLo: 53 ppm/4H,
Ihl-gpg
USOS air: Tt.'A
0.5 ppm or
0.9 mg/=J
Malelc acid
HOOCCHCHCOOH
000110167
(QV1U1VQ-C)
708 orl-rat
L)lrr-3 L)U
S)ing-2 S)U
lhl-2
LDSO: 1560 mg/kg,
skn-rbt
265 Malelc anliydrlde
OCOCKCHCO '
000103316 60 orl-mus L)lrr-3 L)U Pulmonary edema. USOS air: TWA TDLo: 610 ng/kg/
(T5VOVJ) LDLo: 850 S)ing-3 S)U Burns skin 6. eyes 0.25 ppa or 61W
orl-rat lhl-3 1 mg/ra3 TFX:CAR, scu-rac
256 Malic acid
006915157
(QVYQIVA-L)
LDLo: 1500
orl-rat
Unknown
-------
A -70
Sources of Process
_ C fats
" 1)6-689
2)687
3)883
Air, benzene,
sodium perborate
34
Oxidation
Butenes, air
57
Oxidation
204 See phthaltc
anhydride
Maletc acid,
KjSO^, calcium
carbonate, ^02,
sodium cyanide,
sodium hydroxide
38
Hydratlon
Air; benzene (131 kg/
Mg), CO (780 kg/MS),
oaleic acid
Water: maleic anhydride
(3.8 kg/Mg), high boil-
ers (27 kg/Mg), malalc
acid (0.6 kg/Mg)
Emission factors; CO -
1560, benzene - 262.0
Air: butenes, CO, C02,
maleic acid
Water: maleic anhydride,
maleic acid
128
(282)-
1973
132
(290)-
1974
See
above
507. HCg polyester resins;
15% fumaric acid; 107.
pesticides; 57. alkyd
resins; preservative for
oils & fats; paper; perca-
nant-press rosins (text-
iles); plastics; lubri-
cants; copolycers
Kalnly food acldulant;
medicine; mfr of var-
ious eaters & salts;
vine nfr; chelatlng
agn; flavoring
1)6-131
2)687
3)383
5)561
6)639
7)12-832
11)37
12)
13)40
1)6-199
1)6-689
1)6-141
2)688
7)12-847
13)40
-------
A-71
TAiil.K A-t. (Coin
Item
ConpouuJ
Na.ic flnJ
Formula
Clicm. Alotr.
RcBlstry No.
0--1JO
Or.-il Toxlrltv,
Toxic ll.-ir.iinl K.Ulr.Lj
ACULC Cilli::'.ie
ToxU-olor.v
TLV
267
Husityl oxide
(3-reiiccii-2-one,
ft-mctliyl-)
(CIl.jX.caiCOCiLj
W>
263 Kethacrylic acid
000141797
(1YU1V1)
1120 orl-mt
1000 orl-rbc
00007W14
(QVYU1)
9400 orl-rac
L)lrr-3
S)d.g-2
il.l-3
skn
abs-2
L) 11.1-3
skn
ahs-3
L)irr-3 L)U
S)ing-3 S)U
Moderate U'Xlcity
based it. ai.iin:.l
studies. N.irivtic
in high co.icvn;
injury to liver,
kidneys & lunijs.
Readily absorbed.
through skn
LCLo: 10110 ppra,'411,
Ihl-rac
LDLo: 1000 mg/kg,
ipr-rat
LD50: 354 ng/kj,
ipr-mus
LD50: 49 mgAs,
ipr-mus
USOS air: TWA
25 ppm or 100
269 Methacrylic esters
270
271
272
CHjCH^CCOOR
Hethicrylonltrlle
(2-Propenenicrile,
2-methyU)
HjCCCHjCN
45
Methallyl alcohol
(2-Prspen-l-ol,
2 -methyl)
CHjCHCHCl^oa
-------
Source! at
('timpov'.tu!
Free*is
No.
Unhte
TiviUtiu-nt
Totnl
1'fvnlucl t
Etonc
alcohol
24:
Dehydration
W.itfr; acctotie,
dluccconu alcohol
U.ws
RoforenccB
Solv for cellulose 1)6-811
esters & ethers, oils, 2)642
guns, resins, lac, 3)902
roll-coating Inks, 5)561
tains, ore dotation;
paint & varnish-re-
npvers; insect
repellent
Isobuty lene,
nitric acid
62
Oxidation
Acetone cyanohydrin,
aulfuric acid,
inhibitors
Acetone eyanohydria,
sulfuric acid,
alcohols, inhibitors
Isobutylene,
ammonia,
air
165
24T
61
fydrolysis
Esterification
Asooxidation
(Aminoxidatlon)
Water; mcthacrylic
acid, inhibitors
Water: methacryllc
acid, alcohols,
inhibitors
Air! oethacrylic
acid, alcohol
Air: oethacrylonitrila
(5 kgrttg), CO (200 kg/
Kg), isobutylene (ICO
kg/Mg), HCN (1 kg/Kg).
amaonia
30.9 Monomer for large-vol- 1)6-209
(63)- ume resins 6> polymers; 2)707
1968 org syn; many of the 3)903
polymers are based on 4)668
esters of the acid, is
the isechyl, butyl, or
' iosbutyl esters (see
acrylic resin)
" 1)6-527
See
above
321
(706.3)-
1973
(Methyl
nethacrylate)
Almost all polyoers & 1)6-823
copolyners
Vinyl nitrile monomer; 1)6-207
copolyrner with styrer.a, 2)971
butadiene, etc; elasco- 3)903
plastics
Methallyl
chloride,
aodium hydroxide
60
Substitution
(Hydrolysis)
Water; NaOH, NaCl,
methallyl alcohol,
methallyl chloride
Int
1)6-205
2)972
3)903
Isobutylene,
chlorine
59
Chlorlnation
Heavy ends
may be
Incinerated
Int for production 1)6-203
of insec, plastics, 2)971
pharn, other org chea; 3)903
furaiganc for grains, 7)10-723
tobacco, & soil
211 See butyric
acid
Faint remover com- 1)6-719
pounds; lacq solv; int; 2)24
Solv for cellulose 3)907
nitrate, cellulose 5)561
acetate, resins & oils;
artificial leather
Methanol,
acetic acid
185
Esterification
Water; methyl acetate,
methanol, acetic acid,
sulCurie acid
Air: cethatiol, methyl
acetate
Emission factors:
CMitlnnol - 1.0,
methyl acetate - 1.0
1)6-629
7)3-378
12)
-------
A-71
TAKI.K A-I. (C
Item
ConpounJ
Na:.u! and
Fonr-ulo
CliPm. A!>str.
Registry Nu.
(Wl.N)
Ornl Toxlt:lty,
1'n.nifil K;ii ln>'.
Toitl.-olop.v
TLV
27i Methyl acetoacctate
DP (Accloacetic :icld,
methyl i-aler)
CILCliC!l.)CO<)CH3
000105453
(IV1V01)
3000 orl-r.U
Unknown
275 Methyl alcohol
Ctethanol)
000067561
(Ql)
LDIo: 340
orl-hmn
TDLo: 100 TFX:
EYE orl-hon
LDLo: 420
or1-mus
LDLo: 6300
orl-
-------
A-//.
Sou re i- s of Process
^IVl acetJte, 186
Bo?Tu:a,
mcthanol (solvent).
Bulfuric odd
211
212
182
Kethanol, 183
aoeonia
Aniline, methanol, 10A
hydrogen
Pr.ce«
Claisen Reaction
(Sodium fusion)
See butyric
acid
See acetalde-
hyde
Reduction
(Catalytic
synthesis)
Aazonolysls
Alkylation
Antiocl:ttt'il Wnate
Wnrttr:' YtViit Pii-nc
A1 r : liydror.cu
W:iier: nodlum a.ilts,
methanol, sul furlc
acid
Emission factors:
hydrocarbons - 10.0,
CO - 10.0
Water: oils, methanol,
higher boiling organic
compounds
Water; nethylaaine,
dlciethylaaine, cri-
me thy Ian ina
Air: hydrogen, carbon
monoxide, raethylamir.es
Air; methanol, aniline,
methylaniline, N.N-dl-
me thy 1 aniline
Tola!
Product I on
"
*
3210
(7064.4)-
1973
3126
(6378)
1974P
2853
(5177)-
1975
16.8
(37.0)-
1973
24.9
(54.7)
1974
._
Us*'S References
Solv for cellulose 1)6-631
ethers; IngrcJ of solv 2)28
mixtures for cellulose 3)097
esters; org syn
457. Mfr formaldehyde. 107. 1)6-719
dimethyl tccc?httKila:e; 2)713
62, mochylmecl-acryl.n.c, 4Z 5)561
tic thy 1 anilnos, 47. r.echyl 11)37
halldes, 47. acccic avid, 12)
107. solv, 15* nise & ex- 13)40
port; aviation fuel (for
water injection); auto-
motive antifreeze; »-'lv
for nitrocellulose, ethyl-
cellulose, polyvinyl
butyral, shellac, rosin.
manila resin, dyes; ie-
naturant for ethyl alcohol;
dehydratoc for natural gas;
uood & metal finishes;
waterproofing formulations;
coated fabrics
" 1)6-723
3)909
6)642
" 1)6-615
7)13-394
Mfr: HZ Sevin insec, Si 1)6-623
surfactants (e.g., aeyl- .2)724
methyltaurlns salts), 3)944
rocket propel Ian: (-ethyl 5)561
hydrazine)-; inc for ac- 7)2-122
celerators, dyes, pharn; 9)200
fungicides, surface ac- 10)
five agn; tanning; dyeing 13)41
acetate textiles; fuel
additive; polyreriration
inhib; component of
paint removers
Org syn; solv; acid 1)6-71
acceptor 2)110
5)561
Aniline, uwthyl
iodide
103
Alkylation
284A See Process
10A
284B See Process
JOB
Water: Hal, HaOH, methyl
iodide, aniline, mothyl-
aniline, diraethylaniline
Air; methyl iodide, HI
1)6-73
3)910
1)6-931
1)6-933
Acetylene,
acetone,
amnonia
170 Ethylnylatlon
Atr; acetylene, aramonia,
solvents
Water: salts & heavy
byproducts
Stabilizer in chlori-
nated solv; viscosity
reducer It stabilizer;
electroplating
brightener; Int;
metal working; rbr
cement; perfuses
1)6-549
3)914
7)1-624
-------
A-75
TAIU.i: A-l. (Cir.it lii
Itt-m
_Ko,
Compound
tlnrae nnJ
Chcm. A^alr.
RuKintry Co.
Onil Toxlctty, Toxic l-:i;.inl R.-.t-jns
LU,0. mill kg. ACUU- c lu-u-.-.ii:
TI.V
Circlnoi
279
Mt.-t.liYl chloride
Cluth.iue, chloro)
000074373
(Cl)
CK,.
C1
L)irr-l I.)U
lhl-l S) Ui 1-2
S)lhl-3
Sllsht irr f.
narcotic; CHS
da^ayo from
USOS iilr: IVA
100 p|im: or
210 mp,/r.J;
repcaCcil exposure; CL 200 ppm;
sooo livsr. kidney, PK 300 p:W5M/3II
bone ni.irrou f,
damage. Poath m.iy
occur l::KCtcly
or sevei'.il days
after exposure
LCLo: 3000 ppm/uH,
ihl-rat
LCU: 3146 ppm/7H,
Ihl-mus
LCLo: 20.000 psW
2U. lhl-gps
.280 Mathylcyclohexane
(CycloKexane, methyl)
00010S372
0-6TJ A)
LDLo: 4000
orl-rbt
L)U
S)ihl-2
L)U
Lethal in high
concen. Narcosis
& anesthesia in
sublettul doses
USOS air: TWA
500 ppra or
2000 rog/m3
281 Hethylcyclohexanol
(Cyelohexanal, methyl)
282 Kethylcyclohexanone
(Cyclohexanor.e, methyl)
025639423
001331222
(L6VTJ B
*DXLV)
LDLo: 1750 L)U
orl-rbt S)ing-2
ihl-2
skn
abs-2
LDLo: 1000 L)irr-2
orl-rbt S)lng-2
ihl-2
skn
abs-1
L)U
ihl-1
skn
abs-1
L)U
S)ing-l
ihl-1
skn
abs-2
:
Kidney & liver
damage
USOS air: TWA
100 ppm or
470 mg/=P
USOS air: TWA
100 ppm (skn)
or 460 r.g/oi3
(skn)
233 Kethyldioxolane
(Dioxolanc, methyl)
001331095
3000 orl-rat
L)irr-2 L)U
S)ing-2 S)U
ihl-2
284 Kathylene chloride 000075092
(Methane, dichloro) (GIG)
. CH2C12
2136 orl-rat
LDLo: 3000
LD100: 1900
orl-rbt
L)irr-2
S)ing-2
ihl-3
skn
abs-2
L)U
ihl-1
skr.
abs-1
ICLo: 500 ppra/
IYI ir:<:c:is,
ihl-hmn
TCLo: 500 ppm/
8H TFX:BLD.
ihl-hmn
Strong narcotic;
anesthetic;
dermatitis;
dangerous to the
eyes
LD50: 1500 tug/kg,
Ipr-mu8
LD50: 6460 mg/kg,
scu-tnus
LD100: 950 mg/kg,
ipr-dog
LOLo: 2700 ng/kg,
scu-dog
LDLo: 200 mg/kg,
ivn-dog
LDLo: 2700 ms/kg,
scu-rbt
LCLo: 5000 ppra/
2H, ihl-gpg
USOS air: TWA
500 ppn;
CL 1000 ppn;
PK 2000 ppn/
5M/2H
-------
Source* of frocfsi
^^^ Couir-o-.tnil No, Process!
VKuc, chlorine, 150 Chlorlnitlon
sult'urlc acid.
soJluu hydroxide.
HC1
AimorUtfft Wn.ltu
Was: i1:* Tr»-nti:icnC
Air: Oil, (1 lii-./Mg),
CH3Cl ('l3 kc./Ms),
CH2C1., (2 kc/H;;).
CltCl,~(l k^/M.;),
CC1A (1 kg^)
Water: IIC1, sodium
hydi'oxiJe, sulfurlc
acid
Emission t.-ictors:
Cll^ - 1 Ib/ijn,
CII3C1 - 13 1'j/ton,
CI12C12 - 2 Ib/ton,
CHClj - 1 Ib'ton,
CC14 - 1 lb/:on
To i «l
l'i\i
-------
lU-31
285
DP
286
Cr-.rcpinind CIuv.!i. Ab.ilr*
N.iac and Ki'j'.iscry No.
Korauln ' 0'''«N^
Mechylencdl.tnlllne 000101779
(Aniline. 4,4'- (XR D1R 07.)
neehvleitcUl-)
CHj^Nilj),
(C13lt14N2)
Methvl ethyl ketone 00007S933
2-Bu'tanone (2V1)
CILjCOCIljCHj
45
A- 7 7
TAI'.u: K-l. (i\uatiu.cJ)
Oml ToKlcttv, 1VTlt Ii.i7.-inl R:ilt:u:
L0.,(). mK/kK Av-nfi- ClircnU
347 orl-rat L)Ur-3
ulr-2
S) LMR-2
ihl-3
3400 orl-rat L)irr-l L)irr-l
JnC-l S)U
ihl-l
S)ihl-2
ToxU-oloi-.v TLV
t'oiicrntcly high
acute or. 1 1
toxic Itv
LD50: 200 mg/kg.
sen-rat
Local Irr & ' USOS air: TV/A
narcotic 200 ppra or
LCLo: 2000 pom/ 590 e>s/c?
411, ihl-cat
IDLo: 2000 ng/kg,
Ipr-rat
LD50: 616 mg/kg.
Ipr-mus
>.-..
TDLo: 80 nJUT
TFX:CAR, orl-rat
TOLo: 1410 m^/kg
TFX:NEO, scu-rat
^m
287 iiethyl fbrciate
(Foraic acid, methyl
escer)
HCOOCHj
(C2H,02)
000107313
(VH01)
1620 orl-rbt
L)lrr-2 L)U
S)ihl-3 S)U
ing-3
Irr to eyes
LDLo: 10,000 ppra,
ihl-gpg
USOS air: TWA
100 ppm or
250 rag/o3
283 Methyl Isobutyl carbicol
(1-Pentanol, 2-nethyl)
2E9 Methyl isobutyl keCjne
(2-Pentanone, 4-methyl)
(C6K12°>
290 Methyl pentynol
(l-Pcntyn-3-ol,
3-M:hyl-)
00010:306
(Q1V3)
OOOIOS101
(IY1V1)
1410 orl-rat . L)irr-:
S)ihl-3
lng-3
skn
abs-3
2080 orl-rat L)irr-2
IDLo: 2850 og/kg S)ing-3
orl-ous lhl-3
L)lrr-2
S)U
L)U
S)U
Strong irr;
anesthesia
LD50: 3560 ng/kg,
skn-rbt
TCLo: 200 ppm
TFX: IRR, ihl-
ton
Irr to eyes &
mic men; narcotic
LCLo: 4000 ppm/
15M, ihl-rat
LD50: 268 ng/kg,
ipr-mus
USOS
25 p
rag/m
USOS
100
410 i
air: TWA
for 100
air: TWA
ppa or
mg/cP
.
000077758
300 orl-rat
534 orl-gpg
698 drl-mus
TDLo: 7 TFX:
PSV orl-hmn
TDLo: 70 TFX:
CNS orl-hca
Soporific; average
doses cay produce
dermatitis; eruct-
ations; psychoses
& CNS abnormalities;
over doses produce
cona & death
LD50: 750 ng/kg,
scu-mus
291 Methylphenylcarbinol
(Benzenemechanol,
o-roethyl)
000095851
(QYR)
400 orl-rat
(C8H100)
Ethanol, 1-phenyl
benzyl alcohol, a- o«:hyl
292 o-Methyistyrene
DP (Styrene, o-aiechyl)
C6H5.C3H5
(C9K10>
00009S339
(IYRS',1)
4900 orl-rat
L)lrr-2 L)U
S) lng-3 S)U
ihl-2
Linltcd animal
studies shou low
toxlcity
LD50: 2500 tag/kg,
skn-rbt
TCLo: 600 ppm
TFX:1RX. Ihl-hnn
Innediate death
caused by action
on CNS; delayed
death due to
ptitmonla
LCLo: 3000 ppm,
ihl-rnt
LCLo: 3000 ppm,
Ihl-spg
100 ppra;
480 mg/o-1
-------
A-711
Sources of Process
^^^Compoimj No.
Armlno, 195
forLialduhyiie,
hydrochloric acid,
oirervuium
hydroxide
211
See butyl 52
alcohol,
ZnO
Sodium foroate, 139
methanol,
hydrochloric acid
Methyl Isobutyl 244
ketone
Mesityl oxide, 243
hydrogen
*^^
2-Butanone, 171
acetylene.
dicethylacetal
Pro; as i
Condensation
See acetic acid
Oxidation
(Dehydrogena-
tion)
Escerificacion
Hydroge nation
Hydrogenatioa
Ethynylatlon
(Acetylation) "
AsnoclnU'il Wosli-
Wastes Trvntmt'n:
Water: tmunoulum
hydroxide, anaionlum
chloride, & aniline
compounds
Emission factors:
n-bucyl alcohol -
1.0
Hater: methyl ethyl
ketone
Water: sodium chloride,
oodiua formate
Atr; aethyl isobutyl
ketone, methyl isobutyl,
carbinol
Air; nesityl oxide,
methyl isobuCyl ketone.
methyl Isobutyl carbinol
Emission factors:
hydrocarbons - 84.6
-
Tocnl
Product Ion
90.9
(200)-
1975
230
(506.2)-
1974
246
(540.7)-
1973
See
above
..
15.9
(35)-
1973
70.3
(154.8)-
1973
. 94.2
(207.2)-
1974
Usi-a
997. Hfr isocynnatcs (MHI
& polyisocyanacc.i) Tor
polyurclhancs; cpoxy hard-
ener; rbr curing a^n &
antloxldant
Solv: 347. Vir.yl coatings.
14Z nitrocellulose, !'.7.
adhcsives, 12^ acrylic
coatings, 7Z cnisc coat-
ings, TT, lube oil dcvax-
inf, 61 misc incl. alkyds;
paint removers; cemer.ts &
adhesives; org syn; clean-
ing fluids; printing:
catalyst carrier
n
Org syn; cellulose
acetate solv; military
poison gases; fuaigar.t;
larvicides; food ad-
ditive far hnn consump-
tion
Solv fol dyestuffs;
oils, guns, resins.
waxes, nitrocellulose
It ethylcellulose; or;
syn; froth flotation;
brake, fluids
Solv: 35Z nitrocellulose.
252 vinyl coatings & inks;
ICE pharm; 107. Jyn IOC
2S8 & others; 57. magnetic
tape; 4Z adhesives; 117.
Disc, inc 37. extraction
uranium from fission
produc ts
Stabilizer in chlorinated
eolv; viscosity re-
ducer; electroplating
Ri'Ori'ncc*
1)6-657
2)110
3)922
14)3
1)6-719
2)244
5)560
11)37
12)
13)41
1)6-185
3)481
5)561
6)643
1)6-639
2)566
3)924
1)6-815
2)S40
3)910
5)551
6) 644 A
1)6-«13
2)841
3)S41
5)561
6) 644 A
12)
13)41
1)6-553
2)844
3)931
of formaldehyde
(solvent)
brightening; int la
syn o£ hypnotics &
isoprenaid cheo; solv
for polyamide resins;
acid inhib; prevention
of hydrogen enbrittle-
nent; medicine (soporific
& anesthetic
Acetaldchyde,
benzene,
broaine,
magnesium
81
Crignard
Reaction
(Addition)
Water: bromine,
hydrogen brooide,
sodiua bromide,
sodiua hydroxide
Perfumery; flavoring; 1)6-267
dyes; laboratory 3)1017
reagent
Cum«ne
iron oxide
297
Dehydroge na-
tion
Water; aromatic
hydrocarbons, tars
Organic solid, 23.8
from still
bottoms
Incinerated
(52.5)-
1973
26.1
(57.4)-
1974
Polymerization monomer, 1)6-977
especially for polyester; 2)1084
foods; plasticlzers for 3)20;934
paints, waxes, adhesives, 7)19-83
7 plastics
9)23
12)
-------
A-7'J
TAI'.U: A-I.
293 a-Naphthol
DP (1-Naphchol)
299 0-Naphthol
(2-Kiphthol)
300 NeopenCanoic acid
(Plvallc acid)
(CH3).jCCOOH
000090153
(L66J BQ)
2590 orl-rat
9000 orl-rbt
L)irr-2 L)irr-2
S)ing-3 S)lng-3
lhl-2 ihl-2
8kn
abs
000135193
(L66J CQ)
000075989
(QVX)
2420 orl-rat
LDLo: 3800,
orl-rbe
LDLo: 5000
orl-rat
In hnn large
Ingesclsns result
in nephritis, vom-
iting, diarrhea,
circulatory collapse,
aneraia, convulsions
& death. Abs through
skn may cause kid-
ney & eye damage.
LD50: 800 nig/kg,
skn-rbt
See ct-naphthol
LULo: 2940 ng/kg,
scu-rac
LDLo: 100 rag/kg,
ecu-mus
LDLo: 2570 mg/kg,
scu-gpg
-------
A-HO
Sources of Process As«ocl.-it<-il
Compound No. Pro.vss WnMrs
264 See DloroBvteiie EuiUslon f.-^-iurni
glycol propylvnc Kly.:ol -
3*0
Ipnp- nvlde 146 Candcnsat loti Water: amnonta.
nla (Aononolj-sls) ethylene oxide,
ethamjlainitics
Waste- Total
Tlvalrconc Produi-l ion lift*
228 527. Mfr polyester resins;
(501. fl)- 8.57. cello |Juue; 7.51
plastlclzcrs: 47. brake
fluids; craulsiUers &
food add
Rbr accelerator &
stabilizer; Jolv; orj
syn; additive to boil-
er water; waxes & polishes
corrosion in'*.ib; optical
brightencr for determents;
lubricating oil ; wrapping
paper; coatir.j for fruits
& vegetables; phjroi;
baetericides; ccx tiles;
photo; gasoline additive;
herbicide
1)6-891
3)1064
13)44
1)6-465
2)763
5)561
7)13-665
197
See acenaph-
thene
<16A 57Z M£r phthalic anhyd- 1)6-669
(<360)- ride; syn: 2C*. insee (1- 2)772
1973 naphthyl-N-c;echyl car- 3)20;9A3
bamate), 92 i- naphchol, 5)561
77. tanning agents; 3* 7)13-636
mth repell; l£ sur- 9)11
factants; nisc plasti- 13)42
cizers; dyes int; pigments
Naphthalene f
sulfuric acid,
11=B.
soda ash
202A
c acid,
sodluo chlaride
202B
SulConation
(Sulfonating)
Sulfonation
(Sulfonaclng)
Water; calcluo
carbonate, sodium
carbonate, sodium
sulface, naphthalene,
naphthalene sulfonates
Water: sodium
chloride, sodium
sulfate, sodium
hydroxide
Star.ttng poir.t in the nfr 1)6-681
of alpha-naphthoL, alpha-
naphcholsulfanic acid,
alpha-naphthylanine-sul-
fonic acid; srlv (soJlum
salt) for phenol in :he mfr
of disinfectant soaps
Starting point in the mfr 1)6-683
of beta-naphthol, beta- 2)776
naphtholsultonic acid, 13)42
beta-naphthylaaine-
sulfonic acid; leather
tanning agencs
1-Kaphthalene-
sulfonic acid,
sodium hydroxide,
hydrochloric or
sulfuric acid
203A
Substitution &
acidification
(Fusion &
decomposition)
Hater: sales,
naphthalene-
sulfonic acids,
naphthols
Dyes; org syn; syn
perfumes; int; pharn;
Insec
1)6-685
2)779
3)950
4)715
7)13-717
2-Kaphthalene-
ftulfonic acid,
sodiua hydroxide,
sulfuric acid
2033
Substitution &
acidification
(Fusion 6
decompos ition)
Hater: sodium
sulfate,
naphchalene-
sulfontc acid,
naphthols
10.8 Dyes; pigments; anti- 1)6-687
(23.8)- oxldants for rbr, 2)780
1955 fats, oils; insec; 3)950
syn of fungicides; 7)13-717
pharm, perfuses; Int
Tert-butyl
alcohol,
foraic acid,
aulfuric a:ld,
isobutylene,
carbon cionoxide
69
Oxidation
Air: CO,
Isobutylene
Int, as a replacement
for some natural mtrl
1)6-223
2)945
-------
A I! I
TAIIIJ-: A- 1. (i..iil hu:;:J)
Compound
Item t'.t\~a and
No. Formula
3C1C Nltro.inlsol.i
301 p-NitroMaUclc
Cll 0-C.H, -NO,
Cliuni. Atnitr.
Ri-gUtry No.
(VLN)
(WNR MM)
02919S5:i5
(wtiu roi)
Oral To>:Li;!ty,
I'l'jO1 "'"'k!'
4700 nrl-mam
Tusle ll^-iinl R:ulni;
A.-nU- r:i.ront>- Toxi.-olDRv
LD50: '.iOO mu/kc,
1 pr -marz
T1.V Carctno,
..
3K Nitrobenzene
DP (Bcnreno, nltro)
c6»5>;o2
00009S953 TDLo: 200 L)L' L)U
(UMK) TFX:BLU orl-oiira S)ini;-3 S)lny-3
LDLo: 700 iIil-3 lhl-3
orl-rbt skn skn
LDLo: 750 abs-3
orl-doc
LDLo: 2000
orl-cat
abs-3
Cyanosfc due to
formation of
ectliCB.-.;lobln
LDLo: SJO mg/ks,
scu-rnt
LDIo: 400 ng/ks,
skn-nuj
LDLo: 450 tug/kg,
scu-mus
LDLo: 150 mg/kg,
ivn-do?
LDLo: «JO ng/kg,
skn-rbt
USOS air: TWA
1 ppm (skn)
or 5r,is/ar^ (skn)
303C Nitrobenzolc acid
D? (o, p, m)
(WNR XVQ)
303 Benzole acid, o-nltrd
30* Benzole acid, p-nlcro
029805244
(WNR SVQ)
000062237
(WNR CVp)
1960 orl-rat
303 Benzole acid, m-nltro
000121926
CWNR CVQ)
30$ Hltroethane
(Ethane, nitro-)
000075243
(WN2)
1100 orl-rat
860 orl-mus
LDLo: 500
orl-rbt
L)lrr-2 L)U
S)ing-2 S)U
lhl-2
Animal studies
suggest moderate
toxicltv
LD50: 1210 rag/kg,
ipr-rat
LD50: 1960 og/kg,
par-rat
LD50: (30 mg/kg,
ipr-cus
LD30: 770 ng/kg,
ivn-aus
_ LD50: Ii70 ng/kg,
par-mus
LD50: 670 ng/kg,
Ipr-rat
LD50: £50 og/fcg.
Ivn-rat
LD50: 1320 mg/kg,
par-rat
LD50: 610 mg/kg.
ipr-raus
1D50: 6^3 mg/kg,
ivn-uius
LD50: 1190 rag/kg,
par-mus
Injury :o liver &
kidneys of experi-
mental animals
USOS air: TWA
100 or 310 rag/o3
307 Nltromethane
(Methane, nitro-)
(CILjKOj)
000073525
(WN1)
940 orl-rat
950 orl-mus
LDLo: 125
orl-dog
LDLo: 750
orl-rbt
L)lrr-2 L)U
S)ing-3 S)U
lhl-3
May cause anorexia, USOS air: TWA
nausea, voaiting, 100 ppm or
& diarrhea in h=m; 250 mg/m3
kidney u liver
dactage
LDLo: 555 mg/kg,
scu-dog
LDLo: 1.10 mg/kg.
Ivn-dog
LCLo: 2i46 tag/a ,
ihl-mky
LDLo: 750
Ivn-rbt
-------
Sources of
Coi:ip
-------
A-in
TAI'.li: A-l. (foiitlniu-J
Item
No.
N.uic nnj
Korimiln
Clico. Abstr.
Registry Ho. Oral
(V1.N) '-"SO
Toxtctrv. TiV:lr H.tL'nrrf Rjtiiu-,
. ins /KB lU-uti: elm-nit-
ToxK'olot;y
TLV
. C.irclnoi
305G o- i p-Nltroplienol
DP (CMNO)
(WNR xq)
303 Pheiul, o-nicro
309 Phenol, p-nicro)
000088755
(WNR CQ)
000100027
(WNR DQ)
282S orl-rac
1297 orl-rac
350 orl-rat
467 orl-cms
310C Nitropropanes
'
310 Propane, 1-altro
311 Propane, 2-nltro
00010S032
(VW3)
000075469
(WHY)
800 orl-nus
LDLo: 1000
orl-rac
LDLo: 250
orl-rbc
LDLo: 500
orl-rac
LDLo: 500
orl-rbc
312G Nicrocoluene
DP CHjC6Hft802
312 Toluene, o-nitro
313 Toluene, p-nlcro
314 Toluene, m-.ii.cro
CWNR x)
000083722
(WNR B)
000099990
(WNR D)
000099081
(WNR C)
891 orl-rat
2462 orl-cms
2144 orl-rac
1231 orl-nus
1072 orl-rac
330 orl-mus
2400 orl-rbc
3600 orl-gpg
L)U L)H
S)ins-3 S)tnS-3
ilil-3 ihl-3
L)irr-l
ing-1
ihl-1
S)ing-2
ihl-2
L)U .
S)ing-2
ihl-2
L)irr-2
ing-3
ihl-3
skn
abs-3
L)irr-2
S)ing-3
inh-3
skn
abs-3
L)U
S)ing-3
ihl-3
skn
ab9-3
L)U
S)ing-3
inh-3
skn
abs-3
Liver £t kidney
danuge in experi-
mcncal animals
LDLo: 100 r..s/ks,
Ivn-dog
llyperthtmta,
mcthcmo.clobtn-
cnla & CSS
depression
LD50: 75 ns/kg,
ipr-mus
LDLo: 500 ng/kg,
ipr-dog
LDLo: 10 rag/kg,
ivn-dog
LDLo: 65 mg/kg,
Iras-pgn
Moderate
TDLo: 15 ppm
TFX:CNS, ihl-
htcn. GasCro-
incescinal
disCurbances
& Injury Co
kidneys &
liver. Large
doses produce
mecheraojlobi-
nemia £* cyaiiosis
LCLo: 1513 ppra/
5H. ihl-rac
LDLo: 75 mg/kg,
Ipr-mus
LCLo: 714 ppra/
5H, ihl-cac
LCLo: 2331 ppm/
5H, ihl-rbc
LCLo: 4622 ppn,/
5H, ihl-gpg
USOS air: TWA
25 ppra or 90
mg/up
USOS air: TWA
25 ppm or 90
mg/cA
USOS air: TWA
S ppm (skn) or
30 og/ro^ (skn)
USOS air: TWA
5 ppm (skn) or
30 mg/n>3 (skn)
USOS air: TWA
5 ppn (skn) or
30 ng/ra3 (skti)
-------
Sources of Process Assoclatixl \';>f:tc
Cotnpiv.nJ No. PrOi-oss Wnsifs Trf:ilm.-nt
tlf 291 Nitration Water: dinltroplionols,
c nclJ trluitroplienoU.
oxnllc acid, nitric
acid, phenol, p-
nltroplienol
Entsslon factors :
» " " phenol - 2.0, NO, -
2.0, nitrophenol -
1.0
Total
Product Eon Usoa RoftTvnci'S
Syn of o-amiiuiphcnol & 1)6-959
o-nltraaiilsolo; dye 7)13-839
int 12)
11 2)366
3)972
877. Hfr ethyl & methyl
parathions (ir.scc) ; 137.
other incl sy:t dyes, n-
«cecyl-p-anlnj-rhonol &
leather treatments; r">-
duction of phenecidlr.es;
indicator; fungicide;
photo chem
2)366
13)
220 See Hitrodthane
Solv In the coating
ind; printing inks;
propellents; fuels;
pesticides
1)6-743
2)964
3)972
7)13-879
3)552
Toluene,
nitric acid,
eulfurlc acid,
sodium hydroxide
324
Kitration
2)965
5)562
Org syr»; for produc-
tion of toiuidine,
tolidine, fuchsln, &
various syn dyes;
explosives
1)6-1045
2)1140
3)975
7)13-849
3)526
2)1140
5)552
2)1140
5)552
-------
A-K)
TA1UJ-: A-I. (Contlniii.l)
I ten
N.-..UC and
>V rr.m la
Ctii'.ra. Abatr.
ry No.
ml Toxic Uy, Toxic l!;tzunl R..t In;-
TLV
C^rctnoji
31S Nonene
027215958
(SU1)
316 Nonylplienol
(Phenol, n-r.onyl)
025154523
(QR X9)
1620 orl-rat
LD50: 2110
skn-rbc
317 Octylplienol
(Phenol, n-cscyl)
027193:33
(QR X3)
LDLo: 25 mg/kg,
ipr-mus
318 Oxo alcohols
319 Oxo aldehydes
320 Paraldehyde 000123637 TDLo: 14 mg/ks
(s-Trioxana, 2,4,6- (160 CO EOTJ TFX:?S\" orl-han
trimethyl) B D F) 3500 pi'l-dog
OCH(CH3)OCH(CHJ)OCHCH3
321 PEG chloride 000097972 1070 orl-rat
(Polyethylene glycol
chloride)
(AceCaldyhyde, chloro-
dloechylacetal)
L)irr-l L)U
S)inS-2 S)lng-l
lhl-2 ihl-1
TDLo: 14 mg/kg
TFX:PSY, ivn-hmn
TDLo: 71 r.g/kg
TrX:PSY, lais-han
TDLo: 14 mg/kg
TFX:PSY, rec/hmn
Hypnotic &
analgerlc prop-
erties. Habit
forming
TDLo: 12 gm/kg/H
TFX:NEO, skn-nus
322 PenCaerythricol
C(CH2OH)A
000115775
(Ql «x)
Low
low
10 ng/m
-------
Source* e>C
Process
No. troerf*
Wttutc
Tr''iiim*.-nt
Total
rroiliici ton
V::?*
Rofi-rcncos
249 See dodui
Ort; syn; vetting agn;
lube all additive;
polyracr gasoline
1)6-329
Phenol,
nor.enc,
BF,
295A Alkylatlon
Phenol,
diisobutylene
Aldehydes,
hydrogen,
sodium hydroxide
olefin, synthesis gas
Synches Is gas,
olefin, stearic,
natural gas,
C02
Acetaldehyde
295C Alkylation
179
178
82
Reduce ion
0x6 Process
(Oxo alcohols)
Polymerization
Water: phenol,
nonylpltcnol,
boron salts
Fatsston factors;
phenol - 2.0, nonyl
phenol - 1.0
Water; phenol,
octylphenol
Emission factors:
phenol - 1.0,
propylene. - 1.0
Water; COD, BOD,
IOC given
Air: oletin,
synthesis gas
Water; acetaldehyde,
sulfuric acid
Eciission factors:
formaldehyde - 10.0
49 Mfr: 707. non-Ionic sur- 1)5-969
(IDS)- £actant(noiibiodegra
-------
TAM.r. A-l. (Runt liim-J)
Item
KJ.
Compound
N.tme and
Chum. Ab.itr.
Registry No.
(WLN)
Or.-.l Toxlclly,
Ti'r.lc ILiinril R.-.i 1 m-
Aciilc Clin-..il.-
TOKlvvlrH-.y
TLV
Carol
323 Pennine
CII3(CII,).JC1LJ
000109660
(3")
L)U L)U
S)U
TCLo: 130,000 r;m USOS air: TWA
TFX:CNS, ilil-lnnn 1000 ppoi
Njrcocic In high
concon
1-Pentene
(o-n-jtaylcr.e)
CII3(C11J)2CI1:CH2
000109671
(4U1)
L)ing-2 L)U
ihl-2 S)U
S)in2-2
ihl-2
skn
abs-1
Narcotic in hif.li
coucen. Simple
asphyxiant
325 2-Pcntenc
(S-n-Ariylenc)
CH_CK:C!
000109682
(3U2)
Unkr.own
Unknown. Probably
narcotic in high
concen
326 Pcncylenea
(Amylene)
327 Perchloroethylene
(Ethylcne, tctrachloro)
CC1,CC12
(C2ci4)
025377724
000127184
(CYGTYGG)
LDLo: 4000 L)irr-2 L)irr-2 TCLo: 230 ppm
ovl-dog S)ing-3 S)in;-2 TFX:SYS. ihl-hnn
LDLo: 4000 ihl-2 ihl-2 TCLo: 2SO ppm/2H
orl-cat skn skn TFXiEY::, ihl-maa
LDLo: 5000 abs-2 abs-2 TCLo: 600 ppm/lOM
orl-rbt TFX:CNS, ihl-r.ian
Acute effects are
to CNS. Also causes
dermatitic, Irr
to GI trace
LCLo: 4000 ppm/4H,
ihl-rat
LDLo: 85 mg/kg,
ivn-dog
LDLo: 2200 mg/kg,
scu-rbt
USOS air: TWA
100 ppci; or
670 mg/cH
C: 200 ppa
PK: 300 ppa/SM/
3H
328 Perchloronethyl
oercaptan
(Metlunethiol,
trichloro)
C1SCC13
(CCI4S)
000075707
(SHXCCC)
83 orl-rat
L)irr-3
ing-3
ihl-3
S)ing-3
ihl-3
L)U
S) ing-3
ihl-3
TCLo: 45 ppm
TFX:EYE. ihl-hcn
LCLo: 433 ppm/lOM,
ih 1 -hmn
LCLo: 58 ppra/10«.
ihl-mus
LCLo: 53 ppm/ISM,
ihl-cat
USOS air: TWA
800 ug/o3
(Ref 2)
USOS air: TWA
0.1 ppa
(Ref 5)
TCLo: 15 mg/m
68UI TFX:CAK,
ihl-rat
329C o- and p-Phenetidine
DP (CgHuTO)
(ZR 7.02)
-------
Sourcua of
h.- Compound
Process
Ho.
Associated
Wanti'S
Wtistc
Ytvitl sienc
To in I
ivilin:! ton
Ua.-a
References
210
See
Automotive, aviation. 1)6-717
form fuels; rafr of 2)S39
ethylcne & other olcflns, 3)999
solv; blowing ago for 7)14-714
foams; syn rbr
Org syu; blending
agn for high octane
coCor fuel
3)401
Polymerization inhlb;
org syn
3)1000
227
See amyl ilcohoi
1)6-759
131A
See carbon
utrachloride
321 751 Dry cleaning solv; 1)6-417
(706)- n vapor-degreasing solv; 2)538
1973 6% Int. esp fluorocarbons; 3)1002
334 drying agn for tnccals 5)563
(734)- & certain other solics; 11)37
1974 vermifuge; heat-trans- 13)43
305 " fer medium; rir solu-
(674)- tions; paint removers;
1975 printing ink; pharra
131B
131C
Trlchloroethylene,
chlorine,
calcium oxide
218
173
t»hydrochlorina- Atr: trichloroethylene
tion
(2.8 g/kg), pentachloro-
ethene (0.3 g/kg),
dichloroethane (2.35 g/kg)
See
above
1)6-737
1)6-559
7)5-202
Carbon disulfide,
chlorine
156
Calorinatlon
1)6-501
2)712
3)1002
5)562
Hitrophenol,
ethyl sulfate or
ethyl chloride,
sodium hydroxide,
hydrochloric acid,
iron filings
292 Eihylacton & tf.iter; tiaCl. ethyl
reduction chloride, ethyl alcohol,
nlcrophenol, phcn.itidene
Air: ethyl chloride,
ethyl alcohol, KC1
1)6-961
3)1007
7)2-422
-------
A-(:<>
TAliU: A-I. (CV.itliuu,!)
It
N.S
329
Nnui- HllJ
Fcu:uil:i
o-Flicnotidi-.te
(2-Aalnophi'ticColc)
Chora. Abstr.
KcRlstry No.
0000'T4702
(X.R T02)
Crnl Toxii;Uv, T.'stc ll.ir.in! U.-.tlur,
Lisp- TOJ/KS Av-uiLT Clm
-------
A-W
Sources of
n^ffo phenol (
ethyl sul face or
ethyl chloride.
sodium hydroxide.
hydrochloric acid,
Iron filings
Proems*
K.I .
29:
I'n-.vs-j
E thy Lit Ion &
reduction
Associated Waste Total
Wastes Tr.-nt i:ii.*nt Production Use* Referenced
Water: N.iCl, ethyl '-- tlfr of dyes; laboratory 3)1007
chloride, ethyl alcohol, reagent
nltrophenol, plien.il idene
Air: ethyl chloride,
ethyl alcohol, I1C1
Dyestuffs int; p!urm;
medicine; syn sweetener;
rbr antioxldant
3)1003
33
See acetone
1019 M£r: 497. phenolic resins, 1)6-125
(2241)- 147. blsphcnol-A, 147. 2)359
1973 caprolaccam, 47. mechvlated 5)563
1045 phenol, 3Z pUsticizers, 7)15-153
(2298)- 37. adipic acid, 27. sali- 11)37
1974 cylic acid, 2T. nonyl- 13)43
783 phenol, 1J icJucyiphenol,
(1722)- 37. ochor alkyl phenols,
1975 17. 2.4-O, IS pencachloro-
phenol, 2Z chlorophenols,
17. petroleum retininj,
alsc. neg "L
Chtarobenzene,
sodium hydroxide,
diphenoloxide
Cucene, air,
etc
Phenol,
sulfuric acid
33
279A
296'
Substitution
(Hydrolysis)
See acetone
Sulfonatlon
Water; chlorobenzene,
dlchlorobanzene,
chlorotoluene, phenol,
benzene, dephenyl ether
Water; sodium hydroxide
See
above
Water analysis; labora-
tory reagent; electro-
plated tin coatings
baths; ofr of inc &
dyes; pharn; nitrate
analysis; drilling
fluids; bleaching
agn; plasticlier for
concrete; printing;
color inhlb; ion-
exchange resins; tanning
agn
1)6-63
3)1003
4)810
6)647
1)6-125
1)6-915
1)6-975
3)1009
7)15-212
-------
A-'tl
TAIlU-1 A-I. (Continued)
Il«l
No.
Co-pound
Niinc and
Koniuila
Clium. Abstr.
Ri!|>.l>try No.
(VLN }
Oi-.il
u«j(
Toxlcltv,
), n'->/>-S
Voxlc Ihixnrd K.lfln^
Acuti: Chrmiit:
Toxiv-oloRv
TLV Card mi]
33iG Fheny lenodl.imlne
334 m-PhenyleneJi.isiine
335 o-Rienyleneiiamine
336 p-PhenyleneJiamine
00010S452
(ZR CZ)
000095545
(ZR BZ)
000106503
(ZR M)
IDLo: 80
orl-rac
LDLo: 300
orl-cac
LDLo: 300
orl-rbc
LDLo: 100
orl-rat
LDLo: 100
orl-cac
LDLo: 100
orl-rbt
L)irr-3
alr-1
S)inS-3
ihl-3
skn
abs-3
L)alr-2
S)inS-2
ihl-2
skn
abs-2
337 Phosgene
coci2
(CC120)
000075445
(GVG)
L)Irr-3 L)U
lhl-3 S)U
S) ihl-3
338 Phthalic anhydride
D? C,H. (C0),0
OOOOS5449
(T56 BVOVJ)
4020 orl-rat
LDLo: 100
orl-gpg
L)irr-l I.)irr-l
S)ing-l ihl-1
lhl-1 S)U
Not ind ha:ard
LDLo: £0 eg/kg,
scu-rac
LDLo: 17 ng/kg,
Ivn-dog
LDLo: 200 mg/kg,
scu-rbt
Not ind hazard
LDLo: 600 ng/kg,
scu-rat
LDLo: 600 mg/kg,
scu-mus
Skn Jrr. Death
from liver damage.
LDLo: 50 mg/kg,
ipr-rat
LDLo: 170 mg/kg,
scu-rat
LDLo: 100 mg/kg,
scu-dog
LDLo: 17 Eg/kg,
Ivn-dog
LDLo: 200 mg/kg,
scu-rbt
LDLo: 17 mg/kg,
Ivn-man
IDLo: 25 ppji/30H
TFX:IRR, ihl-han
Little vsrning
properties. Where
exposure is
severe pulmonary
adema occurs.
Death cay occur
within 36 hrs
after exposure.
LC50: 75 pptn/30M,
Ihl-rat
LC50: 110 ppm/30M,
ihl-mus
LCLo: 79 ppra/30H,
ihl-dog
LC50: 1037 ppm/
1H, Ihl-mky
LC50: 1482 ppm/
1M, ihl-cac
LC50: 3211 ppm/
1M, Ihl-rbt
LC50: 141 ppm/
30.M, Ihl-gpg
LDLo: 31 ng/ra1/
2CH, ihl-gpg
USDS air: TOA
100 ug/n3 (skn)
USDS air: IWA
0.1 ppra or
0.4 mg/in3
0.05 pp^i or
0.2 n3/n3
(proposed
1974)
USOS air: TMA.
2 ppra or 12
-------
Sources of Process
^_^ Compound No, Procr?.-!
ll^inrobcn:er«, 23 Reduction
hydrochloric acid,
Iron powder
A>Hucl:tleti Waste
W:i!.Tes Treatment
W.itor:
-------
TAUU: A-l. (i\umus
3il B-Ptcoline
(Pyrldine. 3-mechyl)
000109068
(T6NJ B)
Unknown
342 Plperazine
000110850
(T6M DMIJ)
L)irr-l L)U
Excessive abs
can cause urticaria,
vomiting, diarrhea,
blurred vision,
weakness
LD50: 1100 mg/kg,
scu-mus
3A3 Polybutenes
(/*3Ul*/>
344 Polyethylene glycol
025322683
C/l*02*l/)
Unknown
TDLo: 420 gm/kg/Y
TFX:CAR. ivg-oms
345 Polyethylene glycol
chloride
1070 orl-rat
346 Polypropylene glycol
025322694.
(/*OY1*/)
419 orl-rat
3^7 Propane
CU f*lt flj
n-"-n_*wfi-
(C3Hg)
000074986
(3H)
L)0
S)2
Asphyxiant; at USOS air: TWA
high concen has 1000 ppa
a CftS effect
-------
Sources of Process
^Comp..«iul Me. . _
^Plene. 350
oxygen.
V,0_
2 5
Phchalic 205
anhydr idc ,
onsnjnia
Phthallc 205
anhydride.
amcijnia
Acetaldehyde, 89
ancunia,
formaldehyde,
methanol
Ethylerm dichloride, 124
amonia
Butane/butylenes 222
Aiei
ALV J,
136
Hro^-Hs.
Oxidation
taio no lysis
(Substitution)
Asmonolysls &
dehydration
(Anmonolysis)
Chichibabin
synthesis
Aamonolysis
Polymerization
See diethylene
glycol
Associated Waste
Wnsu-s Trv'ntr.u-ii:
Air; CO,, CO, SO.,, 803,
phthallc anliyJrlilc,
maleic anliydriJo,
benzole nctd, atJcliy.lcs
(quantities given)
Air or Wntcr: austtonia.
phthalic anhydride
Air; .iiitnonia, phthalic
anhydride, phi.h;ilo-
nitril, phtlulonide,
phthaliaide
Air: formaldehyde,
ammonia, acetaldchydd.
aoine byproducts
Water: ammonia, KCl,
amnonlun chloride,
alcohol, ethylene di-
chloride, pipcrazinc,
sodiua hydroxide
Air: aianonia, others
Air: C^ hydrocarbons.
alcohols, ethers,
alkylhalides
Total
Production \lf\'f
See "
above
Syn indigo, via
anthranillc acid;
fungicide; ors syn;
laboratory reagent
Int In org syn, es-
pecially pigcents &
dyes; base ntrl for
high temperature
lubricants & coatings;
insec
Vitaains
Corrosion Inhib;
anthel^intic; insec;
accelerator for curtr.g
polychloroprene & epjxy
resins; textile water-
proofing
104.4 Eot-oelt adhesivas;
(230) sealing tapes* special
1967 sealants; cable in-
84 sulation; polyner modi-
USA)- fier; viscosity index
1974 improvers; lube oil
additive
25.8 Chen int (lover coletular
(56.9)- velght varieties); plastl-
1973 cizers; softeners &
44.0 huaectants; lubricar.:s;
(96.9)- bases far cosnetics 4
1974 phara; solv; binders;
netal & rbr processing;
permissible additives to
foods & animanl feed;
laboratory reagent;
Insec, herbicides
Kt'fVrcnccH
1)6-1115
6)648
7)15-455
1)6-707
3)1028
1)6-697
2)928
3)637
1)6-289
2)923
3)1029
13)44
1)6-397
2)932
3)1031
7)15-644
1)6-749
12)
1)6-437
2)948
3)1036
7)10-657
9)204
12)
Solv for cleaning,
extracting, & devaxlag
2)948
Propylene oxide,
propylena
glycol
271
Addition
210
See butane
38.8 Hydraulic fluids; rbr 1)6-899
(85.5)- lubricants; antlfoan 2)949
1973 agn; Int in urethane 9)204
foa.13, adhesives, coat-
ings, elastomers;
plasttellers; paint
foraulations; laboratory
reagent
21,802 Org syn; household & 1)6-717
(48,022)- ind fuel; mfr of ethylene. 2)958
1971 extractant; solv; 3)1058
refrigerant; gas en- . 7)16-547
rlchener; aerosol
propellant; nixturc for
bubble chambers; general
purpose food additives
-------
Compound
It i'(a Nnao end
N.>. Forraila
34S Prop!onaldi-liy«le
CH CH. CIIO
:
L)irr-2 Dlrr-2
lhl-2 S)inS-2
S)in«-2 11,1-2
ihl-2
L)irr-2 L)irr-l
S)ina-l S)ii>f.-l
1'oxUolov.v T1.V C»\
ICla: 8000 i>|W4!t,
ihl-rat
LD50: 6-'0 mB/kS,
scu-rnt
LD50: (i.-'O ng/kg,
scu-inuft
LDLo: 3-'.CO n.S/ks,
skn-rbt
Low coxicity based
on anlr.il studies
LD50: G.-5 niB/k8,
Ivn -RUI s
U)50: 500 tag/kg,
skn-rbt
350 n-Propyl alcohol
351 n-Propyl online
000071238
(Q3)
00o'l07108
(Z3)
LDLo: 5700
or 1 -train
1870 orl-ra:
LDLo: 140
orl-mus
LDLo: 3500
orl-rbt
LDLo: 570
orl-rat
L)irr-l l)U
S)ihl-2 S)ihl-l
ing-2
skn
abs-2
L)lrr-3 L)alr-l
ing-3 S)U
lhl-3
S)ing-3
LCLo: 4000 pfW USOS air: 1WA
4H, Ihl-rat 200 ppm or
LD50: 3^30 mg/kj, 500 og/n3
scu-mus
LDLo: 5 mg/kg,
scu-mam-.
Strong Irr, skn
sensiti:er
LC50: 2310 ppm/
4H, Ihl-rat
LD50: 550 mg/kg,
skn-rbt
352 n-Propyl chloride
CH
000540545
(G3)
L)lrr-l L)U
S)ihl-2 S)U
Irr to nucous
mem; narcotic
In high concen
353 Propylene
(Propene)
000115071
(2U1)
L)lrr-0
S)ihl-2
L)0
S)0
Simple asphyx-
iant. Skn burns
from liquid
form
354 Propylene chlorohydrin
(1-Propanol, 2-chloro-)
CHjClCHOHCIij
(C3H?C10)
000073397
(Q1YC)
220 orl-rat
720 orl-gpg
L)irr-l
S)skn
abs-3
lng-3
lhl-3
L)U
S)skn
abs-1
LCLo: 500 ppn/4H,
ihl-rat
LD50: '80 mg/kg,
skn-rbt
355 Propylene dlchlorlde
(Propane, 1,2-dichloro)
CILC1CKC1CH,
00007S375
(CV1C)
1900 orl-rat
860 orl-mus
LDLo: 5000
orl-dog
L)lrr-2
S)inS-3
lhl-3
skn
flbs-3
L)lrr-i
S)ing-3
ihl-3
skn
abs-3
Dermatitis. Liver,
kidney t* minor
heart daziage in
animals exposed
to high concen
LCLo: 2000 pfW
4H, Ihl-rat
USOS air:
75 ppra or
350 mg/n3
-------
Sources of
Cwnpouiul
«,
ol
Ethinol,
carbon monoxide
__
n-Propyl alcohol.
ammonia
Kpyl chloride,
ia
n-Propyl alochol,
hydrochloric acid
Propylene,
chlorine
Ally! chloride,
sulfurlc acid
..
I'roccss
No. rro.-i-«»
2li Oxidation
(Dehytlro£eoat Ion)
211 See acetic
acid
116 Carbonylation
212 See butyl
alcohol
213 A=nonolysls
216 Aaination
215 Substitution
(Chlorination
267 Addition
(Hydrochlarina-
tlon)
299 Kvdratlon
(Hydrolysis)
306 See Process
No. 267
Associated l.V.3ti;
Air; hyJrof.en,
n-propyl alcohol,
propljnjlduhydc
Emission factors:
acetono - 10.0,
ethylci'.e - 2.0,
CO - 2.0
-- ....
Emission factors;
propyl alcohol - 3.0,
hydrocarbons - 2.0
Air or Water: aamonla.
n-propyl alcohol,
propylamines
Air or Vater: amnonia.
propyl chloride, propylamines
Water; zinc salts,
propyl chloride, tars
-.
Water; sulfurlc acid,
allyl chloride, propylene
chlorohydrin
-
Totul
ProiUi1:: Ion
-
27.4
(60.4)-
1973
39.5
(86.9)-
1974
See
above
42.1
(92.6)-
1973
43.8
(96.3)-
1974 -..
0.20
(0.44)-
1973
1.6
(3.6)-
1974
See
above
_.
4493
(9884)-
1973'
4761
(10475)-
1974
3454
(7593)-
1975
__
_.
_
Uses Rcfori-nces
Mfr of polyvlnyl 1)6-729
acctala & other 2)97!
plastics; syn of rbr 3)1061
chem; disinfectant; 4)373
medicine: preservative; 7)16-551
agriculture
Cellulose preptonatcs, 1)6-719
other i'««P'°rJtes (e-8-> 2)974
Cn.Na) sone of vhich are 3)1060
used as c»ld tnhib in 6)6-367
bread & fungicides In gen- 9)202
eral; herbicides; pljsci- 12)
cizors 4 pham; enulstfy 13)44
ing agn; solutions for
electroplating nickel; per-
fuce esters; artlftc.il fruic
flavors; solv cixtures for
cellulose derivatives
" 1)6-367
7)16-556
Printing ink solv; nail 1)6-723
polish; lacq; wood dyes; 2)981
solv plasticiier; n»:al 3)1061
degreaser; pesticide; 4)375
chen int 5)562'
7)16-552
9)203
12)
Int; laboratory reagent; 1)6-727
rbr chem; dyestuffs; 2)931
textile & leather finish- 3)1061
ing resins; pharta; 7)2-123
petroleum additives; 9)201
agricultural chen; 12)
corrosion Inhib
" 1)6-733
Solv; lot propylaoine 1)6-731
3)1062
Mfr: 46-50Z checicals 4 50- 3)1062
54! nonchealcal; chemical: 6)650
111 polypropylene, 7.7Z 7)16-591
acrylonitrile, 6.7Z Iso- 9)37 .
propyl alcohol, 6.21 propy-13)44
lene oxide, 5.3Z cuzene.
4Z oxo chemicals, oisc ; non-
chem: 34-377. gasoline
alkylate, 6Z polygas
Org syn (introducing 1)6-887
hydroxypropyl group); 2)987
polyurethan« foams; 3)1063
cosmetics; drugs & 7)5-310
food
1)6-981
Int for perchloro- 1)6-999
ethylene & carbon tetra- 2)960
chloride; lead scavenger 3)634
for antiknock fluids; 4)876
-------
A-r/
TAIUJi A-I. (Coutliuiftl)
Ken
No.
356
Cozpouml CliiMo, Abiitr.
Nnro unJ Bci'lstry No.
Horanlii (1.-LX)
Propylene ost.le 000075569
(Propane, 1 .2-0 foxy) (HOTJ B)
OCR,CllClt
~
'C3H6
Or.-.}. Toxlr.ltv, Toxic l-.i2nrit R:aln;;
Ll'io> m«/k>; ,\,,,u. cliror.Lc
930 orl-rat L)irr-2 L)irr-l
690 ovl-sps S)Ii.R-2 S)U
Jlil -2
I.CLo
411,
LC50
411,
ICLo
411,
LD50
oxl>-oloRv TI.V Caret noi
: 4000 ppa/ USOS air: TWA Carcinogen,
^^k__
llil-rat 100 ppm or experimental
: 1740 ppm/ 240 mg/in3
Ihl-au*
: 2005 ppm/
llil-Uos
: 1500 ag/ks.
skr.-rbc
357
DP
Pyridine
NCHCHCKCHCR
(C,.KSN)
000110361
(T6NJ)
891 orl-rat
LDLo: 4000
orl-gps
L)irr-2
S)ing-2
ihl-1
skn
abs-2
L)U
S)ing-2
ihl-2
skn
abs-2
Mild skn irr; CNS
depressant
LCLo: 4000 ppn/
4H, ihl-rat
LD50: 1000 mg/kg,
scu-rat
LDLo: 1200 rag/kg,
ipr-mus
L050: 1121 mg/kg.
skn-rbt
LDLo: 670 agAg,
ipr-gPS
USOS air
5 ppm or
mg/n'3
: TWA
15
353
DP
Resorcinol
00010S463
: 300 ng/kg,
scu-Jog
LDIo: 500 mg/kg,
lpr-f,p?
LDLo : i'jO mg/kg,
scu-GPg
. LDLo: SOO og/kg,
acu-frg
-------
Sources of
CompounJ
^(^.-toiic
chlctroliyilr in,
calcium
hydroxide
Propylene,
Isobutane
__
\
Process Associated Wnar.j
NcL Process Wn:it.'s TrrniMu-r.c
26S Ellcilnation .Mr: ethnnc (S.5 kg/ns) .
(Hydrolysis) huLane (8.5 VS/HU),
prupylcne (8.5 kj'./M,;),
IIC1 (0.5 kg/Ms), |>r..py-
lonc jxldc (*.l k^/Mv;)
Water; calcium chloride.
calcium hydroxiitc.
propylcne glyeol
Emission factors:
ethane, propane &
pro py lone - 17.0, propy-
Icne oxide - 3.2
30* . Epoxldatijn Air; isabutaue, buCane,
(Peroxidjclon) propylene, propylone oxitle,
cthylene oxiJc, acccalde-
hydc (quantities given)
89 See B-Picolene
Tot o.I
Product ton
797
(17535-
1973
798
(1756)-
1974
692
(1523)-
1975
See
above
3.4
(7.42)-
1963
Us.-s
Mfr: 56Z polypropylene
glycols & polyester gly-
cols for polyurcttinncii.
29: propylane Rlycol, 5.X
dlpropylcno filycol, >^ sur-
factants, 5" slycol others
&-iRiac: iuoprcp3uol snides;
synthetic elastomec Otooo-
polymer) ; food add; tubca
M
Rufcrfnci-s
1)6-889
2)964
3)1065
5)562
6)551
7)16-606
11)37
12)
13)45
1)6-993
Syn of plpertdinc. vitanins 1)6-289
& drugs; solv; vacer?roof-
ir.g; rbr chec; denaturaac
2)997
3)1070
for alcohol 4 ant Ifreels
mixtures; dyeing assist-
ant In textiles: bac-
terlcldes; fungicides;
herbicides
5)562
7)16-801
tn-Benzene-
disulfonic acid,
sodium sulfite,
sodium & calcium
carbonate, sodium
hydroxide,
hydrochloric acid,
ether
20
Substitution
(Fusion)
Emission factors'
hydrocarbons - 2.0,
resorcinol - 1.0
11.8 Mfr: 43Z tire & rbr pro- 1)6-97
(26)- ducts, 13X resorcinol- 2)1032
1970 formaldehyde resins; dyes; 3)24;1079
phara; cross-linking agn 7)11-478
for neoprene; rbr tacki- 12)
fler; adhesives for vood 13)45
venteers 4 rbr-to-textile
composites; cedicine; c£r
of styphnlc acid; anilyclcal
agn; explosion detonators;
cosmetics; skn ointcencs;
tanning agn; extraction
of lubricating oil; Ion-
exchange
Dyestuff & pharra int;
chen Int in syn of fine
org chem; light stabili-
zers; resins
Sodium phenate,
C02, hydrochloric
acid or sulfuric
acid
283
Carboxylacion
Water: NaCL or
sodiua sulfate,
hydrochloric acid or
sulfuric acid, phenol,
sulicylic acid
Emission factors;
phenol - 1.0,
HjSO^ - 0.1
6.2
(13.6)-
1969
18.9
(41.5)-
1973
19.9
(43.7)-
1974
531 Hfr aspirin, other 1)6-945
oedlclnals; pteserva- 2)1043
tlve; dyes; perfumes; 3)1087
prevulcanlzatlon Inhib; 7)17-726
org Int; fungicide; 9)24
food additive for 12)
hmn consumption 13)45
-------
363
TAilIJi A-l.
-
I Urn
No.
361
DP
"conpoiiiid
N.I.UI* nuJ
Formula
Sodium accc.ite
(Acetic aciJ,
aodiuRt suit)
NuC.ILO,
2 J 2
Ulpmi ,M,.,tr."
Rtv',l.*rry Ho.
(W1.N)
0001270-rj
(OV1 i-NA-)
Oral Ti'xlslty, Toxlr 1!.
Ll'itl. msj/l.,: Aciili-
3530 oi-l-rat L)Irr-l
S)lng-l
tr.ifd K.i^ljn;
U-.rouli:
DO
S)U
Toxi.'olonv Tl.V Cnrcluoif^^
1J)50: Si'OO ma/ks, -r
awu-nuij
LU5D: 3J5 ng/kg,
ivr.-::uts
Lni.o: 3000 ms/';S>
Sodium hciuoacc
(Ceiuoic acid,
sodium suit)
Sodiun carboxraeChvl
cellulose
(Cellulose, carboxy-
mcChyl ether, sodium
35i Sodiun chloroaceta:e
(Acetic aciJ, chloro-
sodiua sale)
ClCt^COONa
00053:321
(OVR <,-N,V-)
00900W26
003926623
(QV1G 4-NA-)
4100 ovl-rac
LDlo: 2000
orl-rbc
L)0
1)0
S)0
76 orl-rat
165 orl-nus
80 orl-gpg
lorj-.e tioscs by
month cau:;e nausea
& vomitin^. Small
dosos luve no
cficcc
LDLo: 2000 ng/kg,
scu-rbt
LULo: 14CO rag/kg,
tpv-gpj
LDLo: 100 mg
scu-£rg
LD50: 109 mg/kg,
ivn-mus
TDLo: 8600 tng/kg/
IfX:KEO.
ftcu-rat
365 Sodium ferrate 000141537 LDLo: 4000
D? (Fornic acid, sodira salt) (VHQ t-NA-) orl-dog
HCOONa
U)50: 807 mg/kg,
ivn-nus
LDLo: 3000 mg/kg,
ivn-dog
366 Sodium phenace 000139026
(Sodium pheooxide) , (QR &-MA-)
NaOC,Hc
o 3
367 Sorbic acid
(2,4-Hexadieraic)'
ClLj (CH)4COOH
(C6K8°2>
000110441
(QV1U2U2)
7.4
orl-racs
L)lrr-2 L)U
S)ing-l S)U
ihl-1
LDLo: 5000 unk-hum
TDLo: 2600 ng/kg/
65W TFX:CAR,
scu-rat
368 Styrene
(Phenyl ethylene)
(C8H8>
000100425
(1U1R)
5000 orl-rac
316 orl-tnus
L)irr-2 L)U
S)ing-2 S)ir,g-2
ihl-2 ihl-2
LCLo: 10,000 ppa/
DOM, ihl-hmn
TCLo: 600 ppra
TFXrlRR, ihl-hnn
TCLo: 376 ppr,i
TFX:CNS, ihl-hran
TCLo: 20 r.s/m3
TFX:GLi;, ihl-wnn
LCLo: 5000 ppm,
ihl-rat
LCLo: 10,000 ppm,
Ihl-mus
LCLo: 12 gm/m3/
14H, Ihl-gpg
USOS air: WA
100 ppm or
420 rr.g/c3
CL: 200 ppa
PK: 600 ?pn/5H/
311
-------
A-IOU
4
^
B<
Source* of
Compound
He ncid.
>dlun) hydroxide
>n?n 1r ne U _
sodium hydroxide
Process .
No, Process
95 Neutralization Wntor:
sodititu
WnotvEi
nee tic acid,
hyilroxide
Air; acetic acid
315 Salt Formation W.itcr:
(Neutralisation) sodium
sodium
benzole acid.
hydroxide,
bunzoJte
V.lSCl! Tot.-!1.
Tr.'inra-nt Production Usi-s.
D>-e & cplor int; pharm;
cliin;im(k- acid; sonp.t;
pltoto; purification of
glucose; meal preserva-
tion; Keilicino; electro- .
plating; C.innlng; de-
hydrating agn; buffer in
foods; laboratory reagent
5.4 Fungicide; bacterlciJe;
(11.8)- food preservative; cor-
1973 rosion inhib; alkyd resin;
plastici:crs; dyes
References
1)6-311
2)35
3)1102
1)6-1025
2)183
7)3-428
9)199
Cellulose,
sodium hydroxide,
sodium chloroaceta:e,
methanol or echanol
102
Addition
Chloroacetlc and 99
sodium carbonate
Neutralization
Water: sodiua hydroxide,
alkali cellulose, sodium
chloracecatc, chloro-
cecic acid, sodium
glycolate, methanol or
e thanol
29.5 ' Textile ofg (sizing); de-
(64.9)- tergents, soaps, food pro-
1970 ducts (especially dietetic
31.1 foods & Ice crean), vhere
(63.5)- it aces as vater binder,
1973 thickener, suspending agn.
& emulsion stabilizer;
dentifrices; coating paper
& paper board to lover
porosity; drilling cuds;
emulsion paints; pro-
tective colloid; phara:
coscetics; textiles
1)6-325
2)300
3)1105
7)4-645
9)200
1)6-319
2)15 .
^^Pne:
sodium
I sis fit,
hydroxide
Phenol,
fiodiua hydroxide
181
286
Addition
(Fusion)
Water: sodium hydroxide
Sale formation Air: phenol
17.S Reducing agn; oediclne; 1)6-613
(38.6)- ofr of formic acid & 2)566
1973 oxalic acid; org chen; 9)202
rordant; tanning; wall-
paper printing; placing
Antiseptic; salicylic 1)6-939
acid.; org syn
Crotonaldehyde,
keCene
85
Condensation Atr: Crotonaldehyde,
sorbic acid
Fungicide; food pre- 1)6-231
servacive; copolymeri- 2)1073
ration; upgrading of 3)1121
drying oils; cold rbr 7)13-592
additive; Int for
plasticlzers & lubricants;
cosmetics; tobacco
Eehylbenzera
Dehydrogcnation
Water; tarry matter
(v- 13 kg/Hg total) con-
taining styrene cricer,
stilbene, blphenyl,
napathalene, plienan-
threne, ethylphenanthrene,
others
Emission factors:
hydrocarbons - 1.64,
NO, - 0.05, particulate -
0.04
2716 Mfr: 25Z general purpose 1)6-51
(5975)- polystyrenes, 23Z hi&h 2)1083
1973 inpact polystyrene, 153 3)1014
2708 SEE, 6X ARS resins, 5Z 5)562
(5956)- styrenated polyesters, 5X 6)653
1974. emulsion polyoers; 4Z SAS, 7)19-73
1999 3Z styrenc-butadiene co- 11)37
(4398)- polymer resins, nlac; 12)
1975 int; foamed plastica 13)45
-------
A-1'.I I
TAliu: A-1. (L'OIII IniiuJ)
Horn
tjo,
«nJ
C.livcn. Abotr.
Ki-fclftvy No. Or:;l Tuxiclty. Tox tr I'.i ?' ~A>'»tt.- Chn-.-te
TLV
369 Siicctntc .-u-ii!
DP coo;i(Cii2)2a.iO!i
000110156
L)irr-2 L)U
S)U S)U
LULo: 2000 ms/kg,
acu-£rg
370 Succiiunttrilo
000110612
(NC2CN)
371C SuHanillc acid
371 (p-.'flinober.^er.esulfonlc
acid)
(ZR XSVQ)
(ZR DS'JQ)
372 Sulfolane 000126330 1540 orl-rat
(Thiophene, tetrahydro-, CT5SUIJ) 1900 orl-mus
1,1-dioxide)
Highly toxic
LD50: 100 ng/kg,
ipr-rnt
LDlo: 150 ng/kg,
unk-dos
LDLo: 36 mg/kg,
uri-rbt
LDLo: 2300 ng/kg,
unk-pgn
LDLo: 1000 rag/kg,
scu-frg
Unknown. Anicial
studies indicate
lov toxicity &
slight irr
LD50: 3180 mgAg,
skn-rbc
373 Synthesis gas
374 Terephthalic acid
DP C6H4(COOH)2
000100210
(QVR EVQ)
L)irr-l L)U
S)U S)U
LD50: 1430
ipr-nus
LDLo: 757 rng/kg,
ivn-dog
Also dinechyl ester
(OKI), dies thy1
terephthalate
(10VR DV01)
Unknown
375 Tetrachloroathane
DP (Ethane, 1.1,2.2-
tetrachlorc-)
CHC12CHC12
001299907
(CYCYCC)
200 orl-rat L)irr-2 L)U Generally considered
ing-3 S)ing-3 the (rose toxic common
ihl-3 ihl-3 chlorinated hydro-
S)ing-3 skn carbon; produces acute
lhl-3 abs-3 liver conditions -
skn yellow atropliy & cir-
abs-3 riiosis; fatty degenera-
tion of kidneys & heart,
lung 6 serious aembrane
hcmorrhazer & brain
cderna observed in hnin
fatllitles.
LCLo: 1000 ppm/411,
Ihl-rat
LULo: 500 tag/kg,
ipr-rat
L030: 3990
Bkn-rbt
-------
A-lUi
Source.-* oC Proccas
Compound No. Process
iVic anh>\lrldc, 35 HyJro&cnatlan
hydroc.cn,
catalyst
Associated Waste Total
WnHti-s Trratmfii: production Uses
Hfdlclne; org syn; rofc, of
lacq, dyes, esters for
perfumes, succln.itcs;
Rofcrcncvs
1)6-135
2)1035
3)1139
rhoto; in foo*!:) .is a
*
-------
A-IOJ
TAIU.K A-l. (<\nillni:i<.!)
11 em
Compound
Nnnc And
Ko mm In
376 Tctr-ichlovoptitliallc
DP onlisJviile
Cliom. Ahstr,
Kcsls'.ry No.
(WIN)
Oral ToxIcily, Toxic lla::iiril K.itl»!',
LU50, nig/kj-. Ac(ltt. (:l,,.t.;.u.
OOOU703S
(T56 BVOVJ-
/C 4)
TLV
377
load
, tecraethyl)
00007S'JOi'
. .
379 Tetrahydrophthalic 000085433
anhydride ' 0:56 KVOV
(4-Cyclohexene-l,2- GUTJ)
dicarbaxylic anhydride)
2860 orl-rat
L)irr-2 L)U
S)ing-2 S)inf-2
lhl-2 ihl-2
Irr; narcotic;
cacaraccs &
kidney injury
LCLo: 275 ppa/SH/
17D, ihl-gps
LDLo: 500
ipr-mus
380 Tetraraethyler.edianine 00011C501
(1,4-Butanediamine) (Z4Z)
NH
381 Tetraaethylethyler-ediamlne 000110189 LDLo: 15SO
(Ethylenediaalne, (1N1&2S1S1) orl-rat
N.N.Nl.Ni-tetranechyl)
Unknown
382 Toluene-2,4^!iamine
363 p-toluene sulfonamide
C«3C6H4S02:rrf2
(C7H9i:o2s)
000095307
(ZR CZ D)
000070553
(ZSHR 0)
LDLo: 500
orl-rat
L)irr-2 L)U
S)ing-2 S)ing-2
ihl-2 ihl-2
75 orl-bdw
Liver damage;
skn irr
LDLo: 50 ng/kg,
unk-rat
LDLo: 200 mg/kg,
scu-dog
LDLo: 350 mg/kg,
unk-dog
LDLo: 400 rag/kg,
unk-rbt
LDLo: 200 mg/kg,
unk-gpg
LD50: 250 ng/kg,
Ipr-mus
TDLo: 280 mg/kg/
35W TFX:NEO, scu-
rat
-------
A-IP..
SourceJ of Process
nil No,
IJTlne,
sulfur I c acid
AuRnciaU'd
U'astos
Wa.stc
Tivitrt'icn
Totul
1'ivdiiot ton
Vttf
R«fiTrnccn
ar.hydrlde, 20} Chlorination
Wiiti.r: plith.ilic anhy-
dride, *o. 2)1141
mildcvcide in paints
& coatings
-------
lt
-------
A-lOb
oleun
Sources of
Couipoutul
1!Q
Process AsuocLil.'J Wasti:
No. Process Wjiuti** . Tri':itnu-nt
342 Sul Conation Air; toluene ScrubNsr
W.iicr: sodiun sull'ate.
toluene, toluene
»ulfonic acid
Kmlssion factors:
» -- toluene - 1.0
Total
Production Uso.« Rofi-n-nci'S
Dyes; on; syn; acid 1)6-1089
catalyst . 3)1175
12)
2)1141
3)U75
Toluene,
oleum,
PCI.
347
Sjlfonacien &
Substitution
(Condensation)
Air; KC1
W;itor: sulfuric ucicl,
hydrochloric zcid,
chlorine
Org syn; Int in Che
syn of saccharin &
dyes tuffs
1)6-1099
Nitrotoluleae,
hydrochloric acid
or hydrogen catalyse
327
Reduction
Vat:er: toluidinc
Air; ^articulates
Dye
1)5-1055
2)1142
3)1176
7)2-421
Eolvenc (?)
IS
Chlorlnacion
1)6-83
Dichlorobeazene, SB Chlorinatioa
chlorine,
FeCl,
Ethylene dichloride, USA Chlorination
chlorine
Water: chlorine, HCl,
sodiua hydroxide,
ethylene dichloride,
trichloroethane,
Air: HCl, others
Emission factors:
hydrocarbons - 5.0,
CO - 0.1
12.9 Solv in chen afg; dyes 1)6-59
(28.3)- & int; dielectric fluid; 2)172
1973 syn transforcer oils; 3)1184
lubricants; heat-trans- 7)5-265
fer medium; inscc; coolant 9)24
170.1 Kfg of vinylidene chloride; 1)6-409
(374.6)- sol for cleaning precision 2)510
1971 instruments; aerosol pro- 3)1136
193.0 pellant; metal degreasing; 6)656
(425.1)- pesticide; solv for fats, 7)5-159
1974P oils, waxes, resins, other 12)
produces; org syn
Echylene dichloride,
hydrogen chloride,
oxygen
123B
Chlorination
See above
1)6-411
6)656
-------
A-1U7
TAIil.l-i A-l. (OmLliuifv!)
1 1 fin
.No,
39i
Coii pound
N.I.IO and
Trlchlorocchylene
(Etl'.ylcnc , trichloro)
C11C1CC1,,
Chi-m. AI'Htr.
Kc>:ts:ry Ho,
00007S016
(CYCV1C)
Oral Toxlclty,
4: 5360
Tn\lc 1!
Ai-nn-
L)ii-r-l
S)lur.-2
ihl-3
:isiirJ R.-ill'.ii;
Ctiro.iU-
L)(ri--l
S)lhl-l
ToxK'olor.v
TCLo: 160 ppm/S.lM
IKX:CHS, Ilil-hran
TCI.o: 110 ppn/#ll,
i 111 -nun
TLV
USOS air: TWA
100 ppm or 535
C: 200 ppm
Ciirelneui
TDIxs: 351 yS
7EWI TFX:CAR
orl-nus
Narcotic & .me s the- PK: 300 ppm/5M/:il
tic in hivjh conctsn.
KEC STD air
TWA: 100 ppm
Addtctvc. F.itaHr-
ties due to he.irt
failure
LCl.o: 8000 ppm/ill,
Hi 1 -rat
LCLo: 3COO ppm/2H,
Ihl-nus
LD50: 34 mg/kg,
Ivn-tnus
LD50: 1900 mg/ks,
Ipr-dog
LDLo: 150 mg/kg,
Ivn-dog
LCLo: 11000 ppn,
Ihl-rbt
LDLo: 1SOO mg/kj,
scu-rbt
C: 150 ppm
393 Trlchlorofluoro- 00007559*
methane (G.XCG?)
(Methane, trtchloro-
flusro) (Freon 11)
FCC13
(CC13F)
394 1,2,3-Trlchloropropane 000095184
(Propane, 1,2,3-trichloro) (G1YC1C)
395
CHjClCHClCHjCl
1,1,2-Trlchloro- 000076131
1,2,2-Trlfluoroethane (CXCFXCFF)
(Ethane, 1,1,2-trichloro-
1,2,2-tclfluoro)
320 orl-rat
LDLo: 200
orl-dog
L)irr-l L)lrr-l
S)lng-l S)ing-l
ihl-2 ihl-2
ekn skr.
abs-1 abs-1
Anesthesia
L)lrr-3 L)irr-3
S)ing-2 S)ing-2
ihl-2
skn
abs-2
L)U
S)ihl-2
lhl-2
skn
abs-2
L)U
S)U
Cumulative
toxicity
LCLo: 1000 ppm/
4H, ihl-rat
LD50: 1770 mg/kg,
skn-rbt
TCLo: 4500 ppn
TFX:CNS, ihl-han
DSOS air: TWA
1000 ppn or
5600 mg/o3
USOS air: TWA
50 ppra or 300
ng/n3
USOS air: TWA
1000 ppo or
7600 Dg/m3
356 Triethanolamlne
(Ethanol, 2,2',2"-
nltrllotrls)
(CH2OKCH2)JN
000102716
(Q2N2Q2Q)
8000 orl-gpg
L)irr-l L)0
S)ins-l S)ing-2
ckn skn
aba-1 abs-1
Kidney & liver
damage in aninals
under chronic
exposure
-------
A-IDS
Sources ct Process AasociaU'it Wnr.li;
_ Coni>oim,! No. Process Unsti'S Tn-nlnu'!'.:
131A See carbon tetr.i- Emission f;u'Mrs:
chloride trjchlofoccliylonu -
57.0, CC14 - 26.0,
dlchlorocUinno - Jb.O,
Cctrachloroethar.e - O.I
Total
Product ion
205
(451.7)-
1973
176
(388. 1)-
1974
Us.-s
90.t Metal cleaning; 10'
extraction, <:olv, export;
cleaning; extraction solv
for oils, fats, waxes;
solv dyeing; refrigerant
&. heat exchange liquid;
org syn; fumi.;ant; clean-
ing & drying electronic
parts; nfg food additives
for hnn consumption
1)6-417
2)533
3)US6
5)563
7)5-193
9)205
12)
13)46
131B
1,1,2-Trlchloro-
ethana,
oxj-gen
131C
173
130
159
See perchloro-
ethylene
Also pyrolysis of
1,1,2,2-tetra-
chloroethane
P>-rolysts Air: erichloroethar.e,
crlchloroethylene
See dichloro-
difluoror.ethane
152
(334)-
1973
156.2
(344)-
1974
1)6-559
1)6-415
SOZ Aerosol propellucs, 1)6-509
2SZ refrigerants, 1C"
plastics, 57 solv, T"
blowing agn, export &
BlSC
2)712
3)774
6)631B
9)205
13)47
Propylene,
chlorine
305
Chlorination
Air; HCl, chlorine,
chlormaced hydrocarbons
Water; sodiua hydroxide,
chlorir.e, JtaCl,
hydrochloric acid
Faint & varnish recover;
solv; degreaslnj agn
1)6-997
2)965
3)1189
5)562
PerchloroeChylene,
hydrogen fluoride,
chlorine
132
Fluorochlorina-
tlon
Water; sodiua hydroxide,
hydrochloric acid
Air & Water: chloro-
fluorocarbons
Emission factors:
HCl - 2.0, freon - 1.0
Dry cleaning solv; fire 1)6-423
extinguishers; refrigerant; 2)511
alr-condltioning units; to 3)1199
make chlorotrlfluoro- 5)362
ethylene; blowing aga; 12)
polyner int; solv drying;
drying electronic pares &
precision equipment
147
See dlethanol-
uine
44.8 Fatty acid soaps used
(98.5)- in drycleaning, coscat-
1973 les, household deter-
49 gents, & enulsions;
(108)- wool scouring; textile
1974 antlfucie agn & water-
repellent; dispersion
agn; corrosion Inhib;
softening agn,
huciiectanc., & plastici-
zcr; insec; chelatic;
njn; rbr accelerator
1)6-467
2)519
6)622
9)201
-------
A-10-1
TAI'.u: A-I. ((.\mllm.i-.!)
Item
No,
397
Cixnpound
Naac nnj
Fo mm 1 n
Irlothylnmine
(C H ). N
2 5 3
615
Cticra. Ahstr,
Registry Nu.
(WLN)
000121-V4S
(2N2&;)
Oriil Toxlctly. Toxic l-.irsnl Is.-.ilni;
I.»5Q, iiiB/Ki; Acute CI,u.;.U
460 c-rl-rat L)lrr-3 L)in--.l
546 orl-mus S)l"S-3 ilil-'
11, 1-3 S)i, -.:.-;
ilil-J
Toxl.-oliiKv TLV C«rctuofM>n
Kidney .'. liver USOS air: TWA
dar.vaj;!: in cx|X?rl- 25 p\mi ov 100
mont.-.l .ininula mg/n3
LCLo: 1000 ppm/
411, llll-!MC
LD50: 570 r.,s/l
2920 orl-rat
L)irr-l L)irr-l
S)U
Skn trr; narcotic
in the presence
of an inhib
LCLo: 4000 ppm/
4H, Ihl-rat
LDLo: 500 mg/kg,
ipr-rat
LD50: 2320 mg/kg,
skn-rbt
USOS air: TWA
10 ppo or 30
og/n3
-------
Source* of
Process
No.
Associated
U';i!:ti'i*
W.-istc
Tri-:tt mvn
Total
ivtlui-t lou
109 See dletliyl-
aalne
Km I:! si.>» fa.-t.irs:
hydrocarbons - 2.0,
Nil-, - 1.0
139
See dlcchylcne
glycol
13.0 Catalytic solv in che.n 1)6-345
(2S.7)- syn; accelerator act-iva- 2)1159
1074 tors tor rbr; vetting. 3)22;lly
[vnccr.iting & water- 5)552
proofing npn of 7)2-123
quartcrtury nr:noniura 12)
types; curing & harden-
ing of polymers (e.g.,
core-binding resins);
corrosion inhib propel-
lant; print remover
51.3 307. natural s^s dehydra- 1)6-437
(113.1)- tiou, m hur-ectanc, 15?. 2)1160
1973 printing; ink, 127. vir.yl 6)628
50.2 plasticiicrs, 87. polyester 9)204
(110.5)- 4 polyurethan* resins, 12)
1974 12* Udex extraction 13)47
solv
139
See dieth/lene
glycol dibucyl
ether
Solv for gases; coupling
itniniscible liquids
1)6-451
70
See dlisobutylene
Emission factors;
hydrocarbons - 2.0
Syn of resins, & int org 1)6-227
compounds; lubricating
oil additive, raw mtrl
for alkylation in pro-
ducing high octane motor
fuels.
13.1 Syn: 11.&* choline chlo- 2)708
(28.9)- ride, 1.52 others (e.g.. 3)1202
1973 pham.), other quatem- 6)608
ary arr:oniun s«lts; varn- 9)200
Ing agn for natural gas; 12)
efr of disinfectants; 13)47
flotation agn; insect
attractant
Amronla,
carbon dioxide
175
Azmonolysis &
dehydration
(Aomonolysls)
Air! ammonium
carbonate,
ammonia, parciculate
aonoethanolaaine
Ethylene,
acetic acid,
oxygen
84A Oryacetylatlon Air: ethylene,
acetic acid, vtr.yl
acetate, acctaldehyde
3305
(7271)-
1973
3447
(7583)-
1974
3359
(7390)-
1975
683
(1503)-
1«73
638
(1403)-
1974
516
(1136)-
1975
About 76X fertilizer, 12X 1)6-579
anlnal feed, 4Z urea- 1)6-585
formaldehyde resins, 2* 2)1179
oelanlne; plastics; chea 3)1227
Int; stabilizer in er.- 6)657
plosives; nediclne; id- 7)21-54
hesives; separation cf 11)37
hydrocarbons as urea ad- 13)47
ducts); sulfa^lc acid pro-
duction; flare-prooflag
agn; viscosity modifier for
starch or casein-based paper
coatings; reported helpful
in treating sickle-cell anemia
Mr: 39Z polyvinylacetate
laclcs, 16Z polyvlnyi-
acetate resins, 157. poly-
vinyl alcohol (4 butvral,
fornal derlvs.), 71 vinyl
chloride copoiyeers, 4Z
ethylene copolycera, 1%
exports, 27. else; lacex
paints; paper coating:
adhesivcs; textile
finishing; safety glass
intcrlayers
1)6-275
2)27
7)2l-330;340
11)37
13)47
-------
'03
A-Ul
TAIltJ-l A-l. (CoiiCliini-il)
It I'd
No.
N.-iim.' .iiul
Kovmi-.l.-i
r.lu-m. Abstr.
Hi-fi I »I l\v No.
(KLN)
Onil Tuxlclty,
'
T.'xU- H.T.-.anl k.-.lln
Actit i' Chronic
Toxli'oloi-.y
Tl.V
404 Vinyl chloride 000075014
(Ethyleiic, chloro) (C1U1)
ClIjCHCl
L)lrr-2 L)irr-2 TCLo: 20 ppa USOS vinyl
S)ihl-2 S)ihl-3 TFX.-CV5, Ihl- chloride:
hran . T^A 1 ppm;
Anesthetic; liver Cl 5 ppm
Injury ia rats
If rbt; circulatory
& bone changes
la workers
Carcinogen of Che
liver
LCLo: 250 ppa/Mt/
26001 TFX:CAR. Ihl-
rat
TCLo: 250 ppo/S3WI
TFX:CAR, Ihl-aus
405 Vinylldene chloride 000075354
(Ethylene, 1,1-dichloro) (CVGU1)
LDLo: 5750
orl-dog
LCLo: 10,000 ppm/ 10 ppm;
2411, ihl-rat 40'ms/ra3
LDLo: 225 mg/kg, (proposed
ivn-dog 1974)
LDLo: 3700 rag/kg,
scu-rbt-.
406 Vinyl toluene
(Scyrer.e, nethyl)
407 a-Xylene
DP C6H4(CH3)2
(C8K10>
001319739
(1U1R X)
000103383
(IRC)
3160 orl-nus
LDLo: 4900
orl-rat
5000 orl-rat
L)irr-l L)irr-l
S)ihl-2 S)ihl-2
skn skn
abs-2 abs-2
Chronic damage
Co kidneys &
Hver
LC50: 3020mg/raJ,
Ihl-mus
ICLo: 29 og/m3/
13WI TFX:TER,
ihl-gpg
LCLo: 8000 ppm/4H, NIOSH
ihl-rac recornend
LDLo: 2000 mg/kg, scd air: TVA
ipr-rat 100 ppa or
LDLo: 5000 ng/kg, 435 og/n3
scu-rat
408
-Xylene
000095476
(1R B)
LDLo: 5000
orl-rac
LDLo: 1500 ng/Ug, NIOSH
ipr-rat
LDLo; 2500 ng/V.g,
scu-rat
LCLo: 6920 ppm,
Ihl-nus
recocnend
std air: TVA
100 ppa or
435 ng/D3
407C Xylenes (mixed)
(1R X)
-------
A-ir:
Sourer* of
^^ Cotuprmul
z^l^uno,
acetic acid.
oxygen
Process AnHm-liilcil Vn»tu Total
No. Proi-vss Uiitiii-s Tri':ilt!."«I frvini'.-i ion list's Hi-rerrnrrN
84? Oxyacetylatlon Mr: atlwlunr (il.f.S See " 1)5-277
kS/MB)i vinyl aecinte above
(0.34 kg/Mr,), ncetnldc-
hydo (2.0 kr./Mi:) . uthanc
(0.70 kR/Mp.), aortic
acid (0.47 I-.P/MK), methyl
chloride (7. 45 kfi/Mr.) .
ethyl chloride. (0.10
kg/Kg) > f omul Jcliyde
(2.36 kg/Ms)
Water: acutlc .ictd
0.9 kg/>!g), vinyl science
(1.4 kg/Ms), rethyl
acetate (0.18 kg/Ms),
benzene (0.31 Vg/MR)
Ethylcne
dlchlorlde
125
Pyrolysts
1,1,2-Trichloro-
ethane,
sodiua hydroxide
129
Dehydrochlorina-
tion
COD, IOC, EDC i-.lvon
Atr: HC1 (0.1 kc/rtg).
vinyl chloride (5 kg/
Ug), 1,2-dlchloro-
ethylene (0.15 kg/Mg),
1,1-dlchlorocthylune
(0.4 kg/>!g), acetylene
(1.5 kg/>!g)acctaldehyde
Vacer: sodium hydroxide,
sodiun chloride, ferrous
sulfate
Atr: vinylidene chloride
1,1,2-trlchloroethane
Emission factors:
hydrocarbons - 4.0
2432 971 Polyvinyl chloride 1)6-399
(5351)- resins; org syn; 2)534
1973 adhesives for'plastics; 3)1235
2555 plasticals; docorative 7)21-402
(5621)- coatings; Jcacher sub- 11)37
1974 ' stitutcs; drinking cups; 13)i7
1907 printing ink; plasticizers;
(4196)- building and packaging
1975 ind
77.2 Copolynerized vith vinyl 1)6-413
(170)- chloride or a:ryloni- 2)536
1974 trlle to fore various 3)24;1237
kinds of Saran; other 7)21-295
copolyners are also cade; 12)
adhesives; component of
syn fibers; colded,
extrusion & lacq resins
Ethylene,
toluene
121
Alkylatioa i
dehydrogeca-r
tion
Water: toluene, HC1,
aluainun salts, s'odiuz
hydroxide, t.'aCl, tars
Mostly unsacuratcd paly-
esters; solv; int
1)5-377
2)1083
3)1239
13)48
337
See benzene &
ethylbenzene
Solv; int for dyes & 1)6-1077
org syn, especially 2)1201
Isophthalic acid; insec; 5)563
aviation fuel
Xylene feed
349 Separation Sludge: 0.3-1.7 m3/Hg
containing 3 g to 5 kg/
m-* of org material
See
above
1)6-1077
2)1201
337
349
See benzene &
ethylbenzene
See m-xylene
Emission factors:
hydrocarbons - 20.0
485
(1068)-
1973
480
(1056)-
1974
308
(679)-
1973
2,627
(5,780)-
1974
2309
(5,080)-
1975
About 61X syn phthalic
anhydride; vi:a=in &
pham syn; dyes; insec;
motor fuels; exports
About 72Z separated into
individual Isco-.ers; rest
used costly as solv or
in gasolines
1)6-1077
2)1201
3)1246
5)563
6)662
11)37
12)
13)48
11)36
13)48
-------
j; A-l.
It ta
Co:i|»ound
HAIIC nntl
FiTimilii
409 p-Xyleiio
DP CjlUCH,]
(C8H10)
Clu-iii. Ahsrr.
Registry No.
Q.-LN)
Or.-il Ti'xlclty,
I.Li
i>(l,
To* t r K.iyjtnl li;l'. inR
(Wut i; Chronic
ToxU'olofty
TLV
000106-'.23 5000 orl-rac Sec ci-\ylene lOJLu: 2000 rag/kg, NJOSH
(IK D) Ipr-rnt rccommon.!
LDIo: 5000 rag/kg, stJ air: TVA
scu-rac 100 ppn or
I>CLo: 3A60 ppiu, 435 ug/si3
Itil-mus
410C Xyl«nal
(Mixed 2,4-; 2.5-
3,4-; 3,5-)
410 2,4-xylenol
All 2,5-xylenol
412 3,4-xylenol
413 3,5-xylenol
414 2.6-xylenol
415C Xylidine
(ratr.ed 2,3-; 2,r-; 2,5-;
2,6-)
415 2,3-xylldlr.e.
416 2,3-icylldine
417 2,5-rylidine
413 2,6-r.ylidiM
000105679
(QR B D)
000095374
(QR B E)
000095558
(QR C 3)
00010S689
(qa c E)
000576261
(QR B F)
000087592
000093681
(ZR B D)
000095783
000087627
(ZR B F)
3200 orl-rac
444 orl-rac
383 orl-mus
938 orl-rbc
LDLo: 500
orl-rat
LDLo: 400
orl-nus
LDLo: 800
orl-rbc
608 orl-rac
477 orl-=us
1333 orl-rbc
296 orl-rac
479 orl-mus
700 orl-rbc
LDLo: 610
orl-raC
LDLo: 620 orl-rbc
LDLo: 150 mg/kg.
ipr-mus
TOLo: 5600 tag/kg/
28WI TFX:CAR,
933 orl-rac
1072 orl-mus
467 orl-rac
250 orl-mus
1297 orl-rac
841 orl-cms
840 orl-rac
707 orl-mus
LD50: 150 mg/kg,
ipr-nus
L)U L)U Liver i blood da-
S)ing-3 S)ing-3 mage; severe 4
ihl-3 ihl-3 possibly facal
skn skn intoxication
abs-3 abs-3 chrough skn abs
LDLo: 149 ppm,
ihl-mus
LDLo: 120 mg/kg,
ivn-caC
LDLo: 240 ing/kg,
Ivn-rbc
USDS air: TVA
5 ppm (skn)
or 25 mg/B^
(skn)
TDLo: 5600 ogAg/
28WI TFX-.CAR,
skn-nus
TDLo: 5600 og/kg/
28HI TFX:CAR,
ftkn-mus
TDLo: 5600 o
28WI TFX:CAR,
ekn-cus .
TDLo: 4000 mg/kg/
120WI TFX:t(EO,
skn-mus
TDLo: 64,000 eg/kg;
20W1 T?X:NEO,
skn-cus
-------
A-I |.',
Sources- of
ProciMS
No.
Prey ess
Associated
W;i;itt'S
Vaal a
To tn I
33?
349
Sec benzene i
ethylbenriinc
sec o-xylene
1057
(2326)-
1073
1230
(2707)-
197',
1102
(2425)-
19/5
Syn: about CO: DMT & 25Z 1)6-1077
1TA (iisod In polyester 2)1201
resins & fibers, e.g.. 3)1246
"Dacron," "Mylar," 5)563
"T*rylone"); vttaotn 6)663
& pharct syn; insec; 11)37
exports 13)48
71
See m-cresol
Disinfectants; solv. phara,
insec & fungicides; plasti-
ciccrs; rbr Chen; adiitivea
to lubricants & gasoline;
nfr o£ polyphenylene oxida
(2.6-lsoacr cnly); vttclng
agn; dyescuffs
2)1202
Phenol,
nethanol
280
tfethylatlon
Uater: ethers of cresols
& xylenols, cethanol,
phenol
1)6-921
2)1202
9)326
Xylene.
nitric acid,
sulfuric acid,
hydrogen,
hydrogen sulfide
338
Nitration 4
reduction
Water: sodlra hydroxide,
sodiua carbonate
Dye Int; org syn;
phana; vitamins
1)6-1081
5)563
2)1202
2)1202
7)2-421
-------
A-US
TAIII.E A-J. 1SWSTKIAL iMtCAtlli: OIKMKAI.S, !XiM:CA!!ti'S - TOXUMTY
Item
So,
1
DP
2
3
DP
4
5
DP
6
7
8
DP
9
DP
10
DP
11
12
D?
13
D?
14
15
D?
Kortr.uln
Aluminum chloride
A1C1,
j
Aluriinun hydroxide
AKOIOj
Acsonla
Nil,
j
Acr-.oniutn carbonate
(KH ) CO
Ac^onium chloride
NK4C1
Acaonlum sulfate
(KH ) SO
Boron trifluoride
BF1
Bromine
Br2
t.
Calcium carbonate
CaC03
Calcium chloride
CaCl
*
Calcium hydroxide
Ca(OH)2
Calcium oxide
CaO
Carbon dioxide
co2
Carbon noaoxide
CO
Chlorine
C12
i
C!ic:n. Al'Sir.
Registry No.
O.-LN)
007446700
(AL C«)
012645512
007664417
(XI!)
.._
012125029
(ZiC)
007783202
(Z&2 S-04)
007637072
(FBFF)
007726956
(E2)
001317653
010043524
(CAG2)
001305620
001305788
000124389
(OCO)
000630080
(C 0)
007782505
(C2)
DIM I Toxlstty,
37i'0 orl-rac
3£OS orl-mun
_
350 orl-rac
1650 orl-rat
58 orl-rat
__
L
4500 orl-rat
1000 orl-rac
(Ref 2)
4010 orl-rat
(Ref 4)
7340 orl-rac
_
__
T.'xlc l!.i:
.Ao.U-
L)lrr-3
lnR-3
ihl-3
S)U
I.)irr-3
inK-3
il.1-3
S)U
L)lrr-l
Ing-1
ihl-1
S)U
L)irr-l
ing-1
ihl-1
S)U
Dirr-3
ihl-3
S)U
Dirr-3
ing-3
lhl-3
S)U
_
DO
S)ihl-l
DO
S) lhl-3
L)irr-3
lhl-3
5)0
;nril K.I i i in-.
Clin'-.'U-
L)U
S)U
Dirr-1
S)U
L)irr-l
S)U
DU
S)U
Dirr-3
ihl-3
S)U
D irr-2
S)ir.g-2
ihl-2
DO
S) ihl-1
DO
S)ihl-l
DU
S)U
Toxicology TLV
_
LCLo: 10,00(1 USOS air: TVA
pprc/3H, lhl-h=n 50 ppo
ICLo: 20 ppm
TFX:IKR, ihl-ten
Irr to eyes and
cucous r.cm of^
respiratory crack
96 Ivn-irua
Nausla, vomiting, Air: TWA 10 L-.g/m
and acidosis
.^
LCLo: 750 ppm, USOS air:
ihl-rat CL 1-ppn
Corrosive to skn;
Irr to eyes & nucous
LCLo: 180 ppn/7H, L'SOS air: TWA
ihl-rbt 0.1 ppffi
Irr to eyes i upper
respiratory track;
pulmonary edeca
_
Caustic reaction;
ckn irr; affcccs
respiratory system
USOS air: TWA
5 mg/n'
TDLo: 6 pph/100 USOS air: TWA
preg, TFX:TER, 5000 ppa
ihl-rat
Simple asphyxiant
LCLo: 4000 ppa/30 USOS air: TWA
M, ihl-nan 50 ppm
TCLo: 650 ppo/45
M, TFX:CN'S, ihl-oan
Asphyxia; deprives
tissue of oxygen by
reaction in blood
TCLo: 15 ppra, USOS air: TWA
TFX:PUL, ihl-hnn 1 ppm
l.CLo: 430 ppns/30 M,
_
__
__
_.
ihl-hcn
Irr to eyes & nucoua
r.ern; lung tissue ig
affected; pulconary
edenui
-------
Sourci'S of Process Asuocl.sloil W;istc Tulnl
Conipoi'.nil No, rrocoss Wii'M o^ Yivnl::i.-nC Frs'Juct i-.Ml Usoa Ri*Cpri;lK
~ 2)58
3)374
6)701A
2)70
3)305
6)702B
2)73
3)338
2)74
3)389
2)99
3)396
3)469
6)161
3)471
3)509
2)263
4)191
6)723
3)511
4)193
2)264
2)293
3)519
6)727A
2)295
3)520
2)307
3)539
6)728A
-------
1 1 cm
No.
16
DF
17
D?
IS
19
20
21
22
23
24
25
26
27
23
29
30
"31
32
Compound OUT.. Ahulr.
N.tcu1 ami Rcglsti'y No.
Formilii (VIS)
Copper eulfntc 00775S987
CuSO (CU S-0'0
Cuprous chloridu
Cu,Cl2
Cuprous oxide 001317391
Cu,0
Ferric chloride 0077050SO
FeClj (FE Ce)
Ferrous sulfate 0077207S7
(Iron (11) sul£ati) (FE S-04)
llydrochlorous acid 007790923
HC10
Hydrogen 001333740
«2
Hydrogen bromide 010035106
HBr
Hydrogen chloride 007647010
HC1 (GH)
Hydrogen fluoride 007664393
HF (FH)
Hydrogen peroxide 007722841
«2°2
Iron oxide 001309371
(Iron III oxide)
Lithium phosphate 021324403
U3P°4
Manganese acetate 021501768
(Manganese, bis(acetato)-)
C.IUtnO.
46 4
Meta boric acid
(Boric acid) 013460509
(Boric acid) . 013460510
R3B3°6
Nitric acid 007697372
Nitrogen 017778880
«?
t, - 1 1 ?
TAULK /(: <<:..»! lux
Or:il Toxic ttv. TV>\lc !!;.
Ll>r,0> MI-./V. AC,,,,.
300 orl-rat
900 orl-rat Dirr-I
440 orl-r,'.us S)ing-:
14SO orl-r.it
1170 orl-r.us
LDLo: 50
orl-chd
.
DO
Dirr-3
S)ing-3
ihl-3
900 orl-rbt L)irr-3
S)lng-3
ihl-3
LDLo: 80 orl- L)irr-3
gpg S)ing-3
ihl-3
Dirr-3
lng-2
lhl-3
L)lrr-l
_
DU
S)ing-2
ihl-2
_
_
L)irr-3
ing-3
ihl-3
S)ihl-3
__
,,,
,r,\ Knit,.
i:hr.-.ilc
Dlrr-1
S)U
"""
DO
S)0
L)irr-2
ir.j-2
ihl-2
L)irr-2
S)U
Dirr-2
ir.g-3
ihl-3
L)U
S)U
DO
S)0
DU
ing-3
ihl-3
L)irr-2
S)U
ToxtcoloKv TLV Csrclno^fc.
USOS nlr: TOA
1 ng/n3 (as Cu)
_
USOS air: T
Air: 7VA
1 tng/=3
TDLo: 1600 rag/kg/
16 VC, TFX:liEO.
acu-nus
_ ' _
Sinple asphyxiant
In high concn
TCI.o: 5 ppm, USOS air: TWA
TFX:1R-1, ihl-htm 3 ppcn
Strong irr to ciucous
cem, eyes, respira-
tory tract, skn
LCLo: 1300 ppo/30 USOS air: CL
N, ihl-hon 5 ppn
Irr to eyes S upper
respiratory tract;
pulmonary ede=a
TCLo: 32 ppa, USOS air: TWA
TFX.-IRS, ihl-hcn 3 ppn
TCLo: 110 ppm/1 M,
TFX:IRR, ihl-uan
Irr to skn & cucous
aen
Irr to body tissue, USOS air: TWA
skn blistering; eye 1 ppta
irr
Chronic poisoning
affects CN'S; may
result in permanent
disability; upper
respiratory infec-
tion
-_ _
-- USOS air: TWA
2 ppa
NonCo/.ic RRnerally;
simple asphyxiant
In high concn
-------
A-IIS
Sourer.* c!
Waste
Total
Product li'n
Us.-s
Rofrrenccs
2)345
6)733B
2)345
2)553
3)765
2)648
6)734B
4)544
2)619
3)815
2)619
3)816
6)729A
2)620
3)817
6)7353
2)621
3)318
6)7388
3)769
3)885
2)795
3)961
6)7378
3)967
4)738
-------
A-l !
TAIIIJ: A-i (C.uiilimi.-.l)
ItiMa
So.
33
34
35
36
37
33
39
41
42
43
44
45
D?
46
DP
47
D?
43
DP
N;iuio and
Forrculn
Nitrogen dloxldu
NO,
Hiirosyl sulfuric acid
(Sitrosyl sulfate)
KO,HS03
Oxvgen
°2
Phosphates
Phosphoric acid
Phosphorus tribroalde
Potasslun chloride
KC1
KDI
Pctassiua hydrosulfide
(Potasslua sulflds)
HKS
Potassium sul£ide
Scdlua bicarbonate
Scdlum bromide
Na3r
ScdiuQ carbonate
N.2co3
Sodium chloride
NaCl
Sodium cyanide
VtCS
Sodium dlchromate
(Dichromic acid,
disodium salt}
Ciicra. (U'lilr.
(VLN)
(OMO)
0077S27S7
007782447
014265442
0075543S2
(H3 P-04)
007739608
007447407
(KG)
000151508
(KA CN)
001310613
001312733
OOOU4558
(QVA &-!!A)
007617156
(NA E)
000497198
(QVQ &-:iA-2>
007647145
(NA C)
000143339
(NC -HA-)
0105E8019
(NA CR2-05-Q2)
Ornl ToxKttv, Toxic V:\.-.nr.l R.illn.'.
Lt)^Qt uij'./t;;; Acuto fTcvi'c
L)irr-3 L)U
S)lng-3 S)U
lhl-3
1530 orl-ra: L)irr-2 L)irr-2
S)ing-2 ihl-2
ihl-2 S)U
2500 orl-gpg
LDLo: 2430 orl-
rat
10 orl-rat
16 orl-mus
5 orl-rbt
1.6 orl-dog
.4220 orl-rat ~
3500 orl-rat
LDLo: 4000 orl- L)lrr-2 L)irr-l
rat S)lng-2 S)U
ihl-2
3000 orl-rat L)irr-l L)0
4000 orl-nus S)ing-l S)0
TDLo: 8200 mf,/
kg/23 D, TFX:BPR,
orl-hom
6440 orl-rat
liixt.-i'luny TI.V C.irolno^^
TCLo: li-'i ppn, IISOS .ilr: TWA
TFX:rt:i., i!\l-hr:\ 5 ppn
lllf.hly toxic; '
deaJly poison;
the lunj;s, eJona,
6 death
. "*"
Kontoxlc as a pas;
causes burno as a
liquid, douugcs
tissue on contact
ulth skn
TCLo: 100 ng/a3, USOS air: TWA
TFX:IRS, Ihl-hen 1 ng/n3 .
Irr to skn and
mucous cea
Highly toxic 4
corrosive
Large orl doses
cause CI irr, purg-
ing, weakness &
circulatory problems
Poisoning by ing, USOS air: TWA
skn abs, ihl. 5 mg/c3 (skn)
Strong solutions
are corrosive to
skn
"
_ _ _
_
_
117 ipr-mus
Sensitivity reac-
tions occur from
repeated topical
use; ing may produce
corrosion of the GI
tract, vomiting, 4
diarrhea
Irr to eyes
Very poisonous. USOS Air: TWA
Toxicity is Glnllar 5 mg/n3 (skn)
to hydrogen cyanide
Caustic and Irr USOS air: CL TDLo: 160 ng/kg/
100 ug/ta3 69 VI, TFX-.NEO,
ipr-rat
-------
Sourcvs of
Compott'.tvl
Vi«3te
Pro cc ?t s
T.ital
Protluctton
Usos
Rjfurcaces
2)798
3)967
4)739
3)975
3)989
2)897
3)1022
4)824
3)1026
2)951
3)1042
4)853
2)951
4)853
2)1062
2)1062
4)955
2)1062
3)1105
6)7308
2)1062
3)1106
2)1063
3)1107
2)413
3)1107
6)733A
8)129
-------
TAllU: A-'-' ((\ii.l Inn,-.'.)
Iti'ra Xjnw mul
No, Forcr-iln
Ho.
Drill Toxic Ely, Toxic lhi.-.:irJ K.U in)',
U''iO' n'«'-/liS Aciili- Cl.iv.'.li:
ToxU'i
TI.V
49 SoJlum hyilrosuJfU'.o
NaSH
50 So>Uun hydroxide
DP KnOII
0167:1305
001310732
(NA Q)
51 SoJium perborate
NaSO,
007632044
LDLo: 500
orl-rbt
L)lrr-3 L)lrr-2
inK-3 S)U
lhl-2
S)U
40 Jpr-siis
Corrosive to
tissue, vegetable
tissue, S cor-
rosive to nlunlntia
metal in the prca-
rrce? oC tuolsturc.
n.inngo to respira-
tory tract.
I'SOS nlr: TWA
2 n8/nj
52 Sodlun sulfate
007757826
(NA2 S-02-Q2)
i\.ii-rbt
53 Sodlun sulfide
DP Na,S
001313322
53 ipr-mas
Sodlun Eulflce
55 Sulfur dioxide
SO,
007757837
007446095
(050)
TDLo: 57 TFX:
TJNK, orl-hnn
TDLo: 7 TFX:
CNS, orl-h=n
LDLo: 1181
orl-rbt
56 Sulfurlc acid .
DP HS0
007664939
(WSQQ)
2140 orl-rat
57 Sulfur trloxide
SO,
007446119
L)irr-3
ing-3
ihl-3
S)U
L)irr-3
ing-3
lhl-3
S)U
ihl-2
S)U
L)irr-2
lhl-2
S)U
L)ihl-3 L)ihl-2
ing-3 irr-2
lrr-3 S)U
S)U
TCLo: 3 ppn/SD, USDS air: TWA
TFX:PITL, ihl-hcn 5 pp= or 13 eg/
TDlo: 10 ppr./5 M, m3
TTX:PUL, ihl-ban
Irr to eyes; cor-
rosive; poioon;
edema of the lungs;
respiratory paralysis;
Excessive exposure
can be fatal
TCLo: SOO ug/n3, USOS air: TVA
TFX:hfTn, ihl-hcn 1 cg/n3
TCLo: 350 vg/33/3M.
TTX.-Pt^, ihl-hnn
Burns; caustic;
nicrotls. Corrosive
to all body tissues;
ihl cay cause serious
lung dacage; con;act
with eyes tiay cause
total loss of vision;
ing nay cause serious
Injury and death
Corrosive and irr
to mucous acn
-------
A-I'.1:
Si»irci;» of
Procsss
No.
Vastu
Total
Wn «(
U ;;>.<
6)759B
2)106i
3H111
4)960
61730A
2)1070
6)760
2)1070
6)763
2)1070
6)763
2)1096
3)1133
2)1096
3)1134
6)776
3)1136
4)1006
-------
TAIUJ-: A-3. H.IHISTKIAI. IIKU/VNU
I:ec
No.
1
(125)
2
(185)
3
(235)
&
(290)
5
6
7
8
9
10
"
12
(785)
13
14
Compound
N:v.:u: .ind
Koran In
Acctyl chloride
Adi punier lie
p-aralnoyheuol
Amylptienol, n
Aniylphetol, p-tert
Bcnzldine
Benzoyl peroxide
2,6-di-tert-
butyl-p-
cresol
tert-butyl
hydro peroxide
.
. di-tert-butyl
peroxide
tert -butyl -
peroxy benzoate
Calcium stearate
Caprolactao
Caprolactone
Chlorobenzotri-
Koi:lslrv No. Pr:il T.ixUI i v.
'"'''^
000075365
(CV1)
000111603 300 orl-rat.
(SC-'.CN)
000123308 375 orl-rat
(ZR DQ)
00030466 308 orl-rat
(QR D1V)
000092875 309 orl-rat
PR DR D2) 214 orl-tnus
200 orl-dog
000094360
(RVOOVR)
000128370 3510 orl-rat
(IXi&R BQ 1040 orl-mus
E CX) LDLo: 940 mg/kg
orl-cat
LDLo: 2100 ng/kg
orl-rbt
000075912 406 orl-rat
(QOX) 710 orl-mus
000110054
(LX&400X)
000614459 4160 orl-rat
(1XOOVR) 2500 orl-mus
--
000105602 2140 orl-rat
(T7KVTJ)
4290 orl-rat
(GXCCR XC)
^u.IlnHril .,,,,
,U';-2 IB50: 40 o.^/kg.
ihI-3 lhl-2 l|-i--r!tis
skn U)50: 50 n^/kg.
u!)S-3 scu-spg
L)lrr-l L)alr-2 IJJLo: 470 =i;;/kg,
ir.a-2 S)ins-2 scu-cus
lhl-2 LDLo: 1500 cig/kg,
alr-2 scu-gps
S)inS-2
..
TCIxi: 18 r.g/m3/!3YI
TFX:CAS; ihl-tsan
LDLo: 400 eg/kg
scu-dog
TCLo: 12mg/n3,
TFX:PUL, ihl-hmn
l£lo: 700 pptn,
ihl -DUS
LDLo: 250 eg/kg.
Ipr-mus
TDLo: 5500 mg/kg
(preg)
' ' TFX:TER, orl-rat
LDLo: 250 ng/kg.
ipr-mus
LC50: 500 ppm/4H,
ihl-rat
LC50: 350 pfra/4H,
ihl-ous
LD50: 790 Qg/kg,
skn-rat
LD50: 87 mg/kg,
ipr-rat
LD50: 3210 ng/kg.
ipr-rat
-- _- _-
TDLo: 7 ppa
TFX:IRR, ihl-hmn
UJLo: 1410 mg/kg,
skn-rbt
LDLo: 950 mg/kg.
scu-gpg
-.
--
TLV ' Cnrcln^^ft
»
..
USOS TDLo: 10 mg/m3/
carcinogen 56UI
TFX:CAR, ihl-
rat
TDLo: 4500 mg/kc.
30DI
TFX:CAR, orl-rat
IDLo: 2100 ing/kg'
35VI
TFX:CAR, scu-rac
DSOS air: TJ\ TDLo: 25 gm/kg/
5 ng/co3 42WI
TyX:KEO, skn-mus
..
TDLo: 585 mg/kg
TFX:HEO, Ihl-ous
TDLo: 241 mg/kg
TFX:KEO, ihl-mus
--
USOS air: TUA
vacor - 5 ppa or
20 mg/rP
TLV -dust -
1 og/nj
....
chloride
(905)
15 o-chloro-
nltrobcrzenc
000088733
288 orl-rat
135 orl-mus
-------
A-r.'.'.
CIIXHIJALS Ailltt'NMUM - TOXHMTY
Sourct-s ot Process AssocliUotl V;i;itc Totnt
iVtiipou-.ul No. Process VjMt'* Tr.-'H -.:u-iit rtxuluct ton
Knitsstmi f:if ti-rs : IS. 2
liyilrocarbuitu - -.0 (40. 1)-
1975
Emission C;icti>:-s: 279
butaJicuc - JJ.9, (615)-
IICl - 81.0 1975
K. -- .~ > .. _.
228
Usos Ri'fori*nct:s
2)
3)
12)
2)
3)
12)
2)
3)
12)
2)
3)
12)
Dye and pigiunc 2)
raw naterial 3}
4.0 -. . 2)
(8.8)- 9)
1973
14.5 2)
(32.0)- 9)
1973
1.1 - 2)
(2.4)- 9)
1973
1.1 2)
(2.4)- 9)
1973
Emission factors: . 433 2)
ehloroethylene - 1.0 (951)- 12)
1975
2)
12)
2)
-------
It.'n
N>.'i
16
17
IS
(965)
19
20
21
22
(1170)
23
24
25
26
27
23
29
Cotll|KMll>tJ
Name nti.t
Fori:ml:t
p-c!iloro-
nltrol'cnsrne
Chloroprouo
(1.3-but.iJlenc,
2 cliloro)
Chlorosulfonlc acid
Chlorotrifluoro-
ne thane
Citronellol
(6-octen-l-ol,
3,7-dioethyl)
Cyclohexanone pxine
Cyclooctadiene
Tris(2,3-dibromo-
propyl phosphate)
CTBPP)
Dibutyloaleate
m-dichlorobenzer.e
Dichlororce thyl ether
2 F4-dichlorophenol
Diethylene- .
triamine
N.N-dimethylacetatnide
,\-\V."i
TAHLK A-3. (Coialiiiu-il)
Clien. Ali;.l r.
Rrxlst'rv tin. Oral Ti.x (.-.( (v. Ti'xlc llnz.-ir.l K.Kln,-.
(KLX) '-"50- ""''t.1'- jWulr iMtrvitK- Tnsli-i'lunv TI.V
OOOIOIVOS 1414 orl-ams -- -- IJIOO: 4JO nj-./kg. USOS air: IV. \
0>'N'R 1HO t|.r-m.im 1 rK-./mJ (skn)
000126««3 U)Io: 1600 TCLo: SO f;m USOS air: 1VA
(1UYCIUI) orl-rat TFX:CN.S 25 ppia (,-ik-j)
TDU: 39 lu-j/n3/ or 90 las/m3
41I/4SU
TFX:MUT. ihl -r.it
LCLo: (-00 =i;;/n3/
8H, ihl-r.-.ui
LCLo: 2500 ns/n3/
8H, ihl-cac
LDLo: 96 nj/kg,
tvn-rbt
007790945 -- Details unknown
(H S-03 G) (higli toxicity)
L)irr-l
S)ihl-2
000106229 LD50: 4000 mS/ks,
(Q2Yi3UY) icis-mus
000100641 -- LU50: 250 aig/kg,
(L6YTJ AUNQ) tpr-mus
-T
1010 orl-rat
000105760 3730 orl-rat -- LD50: 150 ng/kg.
(40V1U1VOR) ipr-nus
L)irr-l L)irr-2
ing-2 alr-1
ihl-1 S)ing-2
alr-1 ihl-)
S)ing-2
000542831 210 orl-rat LCLo: 8 ppo/4H, USOS
(C101G) ihl-rat carcinogen
LC50: 25 cg/n3/
. 6H, ihl-nus
LD50: 280 ag/kg,
skn-rbt
000120332 580 orl-rat LO50: 430 tig/kg,
(QR BG DC) 1600 orl-mus ipr-tnus
000111400 1080 orl-rat L050: 74 trig/kg, Air: TWA
(Z2M2Z) ipr-rat 1 ppm (skn)
LD50: 1090 mg/kg.
skn-rbt
000127195 -- -- -- TCLo: 20 ppm USOS air: TWA
(1VI11&1) . TFX:SYS, ihl-hir.n 10 pirn (skn)
TDIx>: 600 ng/kg or 35 mg/rv3
TFX:TER, ipr-rat
1050: 2240 ng/kg,
skn-rbt
^ '
Care 1 i^B|^_
-;
_.
^^
..
__
-
»
TDLo: 100 ppb/4WT
TFX:CAR, ihl-rat
TDLo: 135 ng/kg/
58D1
TFX:CA8, scu-raC
TDLo: 5 mg/m3/
82DI
TFX:NEO, ihl-ir.uS
TDLo: 5520 ing/kg/
23WI
TFX:tZO, skn-mus
._
.
-------
Sourcea oC
AdsociatoJ
Wnalc
Trvii(it:i-ni
Totnl
Pro.lui.-r!, >u
Usos
2)
2)
Emiss ton fncr^rs;
H2S04 - 1.0,
chlorobenzene 5.0
Kmlsston fnct.-rs;
CClj, - l.o, KC1 - 1.0
63
(U8>-
1968
11
(2*)-
1975
2)
3)
U)
2)
3)
U)
2)
Emission factors:
hydrocarbons - 3.0
11
(24)-
1975
2)
12)
5
(11)-
1973
2)
9)
2)
3)
12)
2)
2)
2)
9)
2)
-------
TABU; A-3. ti;.>m iuu.>
onoiof.oio
W^Nl&l)
000079447
(CVNlil)
000057147
(ZN1U)
000534521
(WNS K C
EJM)
000142847
(3K3)
--
000151564
(T3MTJ)
000103117
(442&IOVIU1)
000093011
(I50J BVH)
000516239
(QIYCIC)
OOOH8741
(G 6-R)
000124094
(Z6Z)
Or:il Toxli'llv, To\K ll.i/ar.l K;i t t.n^
Lll.-l(1, t..;;/Kn' iU.,.,,. ' ,:i,7,,,,|;. TovU-oUn-v
2340 orl-r;ic 11)50: 11KO m;/kg,
i pr-mti:>
LUiO: 96L us/kg,
scu-mts
LD30: 1370 ms/kg,
skn-rbc
UlLa: 1.0 m&/kg,
scu-aus
122 orl-rac L)lrr-3 LC50: 252 pfinAll,
S)lns-3 Ihl-rac
ihl-3 LD50: 60 mg/kg,
fikn i pr -rky
abs-3 LC50: 3575 ppra/15M,
Hi 1 -dog
25 orl-rat TCLo: 1 ng/m3
47 orl-nua TFX:CKS, Ihl-han
LCLo: 40 mc/m3.
Ihl-cac
--
930 orl-rat LCLo: 1000 p|W4H,
ihl-rbc
LD50: 1250 ng/kg,
skn-rbc
~
15 orl-rat -- LCLo: 25 ppn/8H,
Ihl-rac
LC50: 400 n^/m3,
Ihl-mus
LD50: 3800 ug/kg,
Ipr-rat
.-
127 orl-rac TDLo: 600 Pg/n3
425 orl-mus TFX-.EYE, Ihl-hmn
2300 orl-dog
541 orl-gpg
90 orl-rat ~ LCLo: 500 ppn/4H,
Ihl-rat
LD50: 200 r-.g/kg,
skn-rbt
3500 orl-rac L)irr-l L)irr-l
4000 orl-Dus S)lng-l
1700 orl-cat
L)lrr-2
S)ing-2
ihl-2
11 .V C.irclnW^^B
TOIo: 17 jm/kg/
7a.'l
TKX:CAK, skn-«u»
TDlo: 2560 mg/kg/
641
TFX:NEO, Ipr-nus
TDLo: 5200 mg/kg/
26WI
TTX:CAR, scu-rau5
USDS air: TWA TDlo: 7902 mg/Tig/
0.5 ppra (skn) 30WC
or 1. mg/m3 TFX-.CAR, orl-ous
USOS air: TWA'
200 ug/o3 (sko)
~
~
--
USOS TDLo: 20 ng/kg/
carcinogen 6701
TFX:CAR, scu-rac
TDLo: 235 mg/kg/
76WC
TTX:CAR, orl-mus
"
USOS air: TWA
5 ppm (skn) or
20 mg/nj
_
-- ~~
«
44 Hcxatnc t h y I c ne -
diacrmonium-
adlpate
-------
A-I.'H
ces of
Co-umuiul
At:suc: latcd
Wustc
Total
rr.-.ltu-l 1..
1.9
(4.2)-
1973
2)
9)
2)
1.8
(4.0)-
1975
2)
3)
12)
2)
3.5
(7.7)-
1973
2)
9)
8.3
(18.1)-
1973
2)
9)
2)
2)
2)
2)
2)
12)
Emission factors:
hydrocarbons - 2.0t
HC1 - 1.0
Emission fJccorg:
idiponicrile -0.1
1.5
(3.2)-
1975
350
(770)-
1973
2)
3)
12)
2)
3)
12)
9)
-------
TAlllj: A-3.
It on
No,
45
4f
47
48
49
50
51
52
53
54
Coi::[»ou-.nl
KiTKlll.l
Hexaniu thy 1 phosphoric
ac iJ» Irl.untJc
(l>lio»|'liorlc trl-
arclttc, licxauwChyl)
2-lifx.inmu!
(ii-l'iil \l nu'lhy I
kcUniu)
3-hcxanonc
(ethyl iH'opyl
keconc)
Hexylalcohol
Hydrasine solutions
(data for hydrazlne)
lonone
IsopenCane
Isophthalonltrile
Isopropyl ether
(propane, 2,2'-
oxybls)
Lactic acid
Clicm. Ahatr.
Registry No. Oriil Tuxlclty,
(U'LN) '-"-iO- "'.'k*'-
CO()fiS03I9 2630 orl-rnt
(K!l&3rOlNl£i
3PO)
000511786 :5'n> ,'fl-rat
(..VI) :iK. .u-l -,-.,,;
3360 orl-rat
(iV3)
000111273 720 orl-rac
(Q6) 1930 orl-mus
000302012 60 orl-rat
PQ)
4950 orl-rac
(LCUTJ A E E
F1U1V1 & L6UTJ
A B1U1V1 C C)
000078784
060103203
(nr & ov)
000050215 3730 orl-rac
(QYVQ)
T.-xl.- ll:u:iir.l K.itin,; 4^^
A^-.iU- Cn-,.-,iU- Tosli-olov.v TI.V Curvlnurfl^B
U)U>: 3500 ws/kg, -- Rcccncly reported
skn-rat squ.imoua cell
carclnof.cn
UUo: I'dOO pirn/711, USOS air: 1VA
illl-J'.IV. ' ll'O l'!-i:' '
410 ms/'ii'
LCLo: 4000 pprj/4H,
Ihl-rac .
LC50: 570 ppmAH, USOS air: TWA TDlo: 400 mg/ke/
Ihl-raC 1 ppm (skn) or 5'..'I
LD50: 252 ppm/4H, 1.3 mg/ra3 TFXiCAR
ihl-mus
- .
"
TDLo: 800 ppra/5M/ USOS air: TWA
IFX:IRR, Ihl-hma 500 ppm
LD50: 812 mg/kg,
Ipr-ous
Lnto: 471 mg/kg,
idu-hn-.n
55 Louroyl chloride
56 Lead haphthenate
(naphtheoic acid,
lead sale)
57 Melacnine
000108781
1600 orl-mus
58 Kethionine
59 Methyl acrylate
60 MeChyl-n-arayl keCone
(2-kepCanone)
61 Methyl bromide
62 Mechylcne dilsocyanotc
(KDI), (p,pl-diphanyl-
aethane diisocyanate)
000096333
(1U1V01)
000110430
(5V1)
000074839
(El)
300 orl-rat
1670 orl-rat
LCLo: 1000 ppm/4H,
ihl-rac
LClo: 4000 ppn/4H,
Ihl-rat
ICLo: 35 ppm
TFX:CNS, ihl-hmn
TOLo: 8000 ppm
TFX:SKM. skn-hmn
LCLo: 514 ppm/6H,
Jlil-rac
LCTx>: 300 ppra/9il,
Ihl-gpg
TCLo: 0.13 ppn/3011
TFX:ALR, ihl-hmn
LD50: 17 mg/kg,
ipr-mu3
USOS air: TWA
10 ppci (skn)
USOS air: TWA
100 ppm or
465 mg/m3
USOS air: CL 20
ppm (skn)
USOS: air
C 0.02'ppra
-------
LSourcc5 of process
Compound No.
Prcvosii
\;:ir,t\-t
Wll:iti!
Tn .1 Ireful
Tutlil
l'r..,li:ct l.-
1973
53.9
(118.6)-
1973
2)
2)
12)
2)
9)
2)
9)
2)
9)
2)
9)
2)
2)
2)
2)650
-------
A-I'll
TAIUJ: A-:I. (cmii iiun-J
Itca
No.
63
w
(-'665)
65
66
67
63
69
70
71
72
73
74
75
76
77
78
<3270)
79
80
81
Name miJ
Forinuta
Methyl lonoiie
Methyl rethacryl.ite
Ox.ilic acid
Methyl salicylate
Para formaldehyde
(cistakenly listed
as s-trixane or
cyclic sym-Crioxane
In rcf 2)
Peracetlc acid
2-pentanone
(methyl propyl
ketone)
Piperldine
Propyl acrylate
Propylene
carbonate
Salicylaldehyde
Stearic acid
Sodium carboxy-
methyl cellulose
Sorbitol
Stllbene
Tannic acid
TerephthalonlCrilc
Tetraethylerte-
Slycol
Tetrahydrofuran
Chcc. AI'Ktr.
(Km
-
000030626
(lUYVlll)
000144627
(QVVO.)
OOOU9368
(QR BVOl)
..
000079210
(QOV1)
000107379
(3V1)
000110394
CI6MTJ)
--
000090028
CVHR BQ)
000057114
(QV17)
003959533
(Q1YQYQYQYQ
-
001401554
000623267
(NCR DCN)
0001121)07
(Q2020202Q)
000109999
CT5GT.J)
Or:il To::i».it v. Toxli- ll.-i.-vir.l R.-illni;
LU50, n. .<«. Acult IV.viilc ' Toslv-olf«:v TI.V
--
6300 ocl-t-.i';: L)irr-l S)ln.;-l TCIo: 125 PI-.U . USOS n!r: I'.'A
1J>L.>: 500(1. S)ln«-2 ihl-l TFX:CMS, ihl-lmm 100 |i|«i or
orl -ilnj; thl-l' l\'l.«: tr»0 I.K-.-'M* 410 D;: 'm-^
lil ..: 'J /'ill |-|-;u.
ihl-r.it
LDLo: 1000 ciB/kg, LDU>: 700 mi-./kj-. USOS air: T..'A
orl-dos IFX:UNS, or I -linn 1 tns/n-1
837 orl-rat -- -- LDUj: 170 ms;/ks.
2100 orl-doj*. orl-ha;n
LDLo: 1500 ng/kg.
scu-sps
1540 orl-rat
10 orl-gpg
3730 orl-rac -- LC50: 2000 ppm/4H USOS air: WA
200 ppra or
700 mg/o
400 orl-rat LCLo: 4000 ppn/4H
ihl-rat
~
_.
LDLo: 1000 mg/kg
LD50: 22 ng/kg,
ivn-rat
LD50: 23 mg/kg,
ivn-cius
LDLo: 5 mg/kg,
ivn-cat
*-
. .-
5000 orl-rbt, L)irr-l L)irr-l LDLo: 75 ng/kg.
LDLo: 2000 mg/kg, S)ing-2 scu-cius
orl-mus ihl-2 LDLo: 10 cng/kg,
ivn-mus
LD50: 699 mg/kg.
i pr -mus
--
3000 Irl-rat LD50: 500 ms/kg, USOS air: WA
Ipr-rat 200 Pfn ar
590 mg/rn3
J^'
Crtri-lno\:i^^^P
"^P~
..
-.
--
..
..
..
~
_.
..
__
TDLo: 860 mg/kg/
UI
TFX:NEO, scu-rat
...
~
TDLo: 4450 mg/kg.
17WI
TFX-.CAR, scu-rat
_M
_
_.
-------
Sources of
Process
Ku.
Ai.soclat.'il
W.I SI l-3
U'.i s I a
Tivatn.-nt
Total
I'roJuct loo
Uses
En I as I on factors:
auuumc - 111.'i. liCN
6.8. i-u-'.hvl i.:oilMorv-
l.iic - j.h. !.-.Jio-
2)
3)
12)
2)
2)
2)
2)
2)
2)
2)
2.2
' (4.8)-
1973
2)
9)
2)
31.2
(68.5)-
1973
72.0
(158.0)-
1973
2)
9)
2)
9)
2)
3)
12)
2)
5.5
(12.D-
1973
2)
9)
2)
-------
No.
82
(J354)
S3
U39S)
84
S3
86
87
88
89
90
91
92
93
Compound
Formula
2,4-taluone-
dltsocyaiuce
(isocyaiuc acid.
oseeliyl plvnylcno
esli-r)
1.1,1-trichloro
eclunc
Owthyl chloroform)
2.4,6-trichloro-
phonol
Tricoresyl-
(phosphcric acid.
trltolyl ester)
Triethylene-
glycol cono-
ethyl echer
(Douanol IE)
Trlethylene-
glycol co na-
me thy 1 ether
Trlethylene-
tetramine
6-trioxane
(formaldehyde
cyclic tricer)
Trine thy lol
propane
Trlphenyl-
phosp'oate
2-vlnyl pyridlne
Xylylece
diisocyanace
,A,,,
C'.i.-m. Al>xtr.
Roplntry No. Or.-^l Toxlctiy,
00007 IJ-5G 5u60 ovi-rt'C
(CXCC)
000033052 S20 orl-rut
(QR BO DC
FC)
001330785 LDI.o: 4680,
crl-rat
LOLo: 500.
orl-dog
LDLo: 100.
orl-rbt
000112505
(Q2020202)
..
000112243 4340 orl-rat
(Z2H2M2Z)
000110333 800 orl-rat
CI60 CO £)TJ)
~
000115865 3000 orl-rat
(ROPO&ORMR)
-
A-l I)
T.'\K- ll!i.i»r.l linCii)-.
Ai-iiio Cluvi'lo Toxtcoli'i-.v TLV CnrclnoR.'ii
I,)irr-3 L)trr-3 Tni^>: 0.5 piw USOS nir:
S)in>-.-2 S)!.n;-l TFSMRE, ilil-lium CT. 0.02 ppa or
llil-3 alv -3 LC50: I'.p|W-'.ll, 0. 14- ms/m3
ilil -rat I1IOS1I roc VI »til
l.Cirt: S p|«i/'ill. Air: WA
iul-i-t-t 5 |.|-b
L)fvr-l l.)ii-r-I T'"U.: J'.d piv.i USDS :,if: K.V,
in^-l S)iit;;-I IfXM'SY, ihl-inaii 3JO Pfn or
S)ilil-2 ilil -1 TULo: l/-0 ppr,i/70M 1900 ng/n3
TFX:CNS, ihl-ltiun
LD50: 276 mg/kg,
ipr-rat
" -- -- .. _-
ID50: 820 mg/kg,
sfcn-rbt
-- . ^ -- -- _- _»
LD50: 100 cig/kg,
scu-cat
-------
ot*
Vnste
Wa a
Total
Vr i.-1 ion
f.-K-cnrs;
boua - 14.0
2)631
3)
12)
2)
3)
12)
2)
10.6
(23.4)-
1973
2)
9)
13.2
(29.1)-
1973 .
9}
2)
9)
2)
2)
-------
A-135
TABLE A-4. EMISSION FACTORS NOT LISTED
IN TABLE A-l
IOC
Item
No . Compound
16 ' Acrylic acid and
Acrylate Esters
17 Acrylonitrile
Emission Factors,
Compound
propane
propylene
acrolein
CO
acetaldehyde
formaldehyde
formic acid
ethyl acetate
acetic acid
acetone
propionaldehyde
ethylene
CO
propane/propylene
pyridine
ethylene
ethane
acrylonitrile
acetonitrile
methane
HCN
N02
furan
butene
benzene
methanol
toluene
ethanol
butanes
acetaldehyde
misc
Ib/ton
.65.0
49.0
29.0
24.0
15.3
7.3
3.0
2.0
1.7
0.8
0.5
0.5
158.6
110.0
5.2
5.1
3.9
1.8
1.4
1.3
1.3
1.1
0.9
0.8
0.6
0.2
0.2
0.1
0.1
0.1
0.2
-------
APPENDIX B
ORGANIC DYES AND PIGMENTS-TOXICITY. PRODUCTION,
WASTE, AND USE DATA ASSOCIATED WITH DYES AND
PIGMENTS AND THE RAW MATERIALS,
INTERMEDIATES AND INORGANIC CHEMICALS USED
IN DYE AND PIGMENT PRODUCTION
-------
11-1
TAi-.ii: 11-1. OUCANU? PYKS AND i-iaois, KAW UUKKI.AI.S-TOXICITY
Item
No.
1
2
3
4
Compound
N\iuu: And
Fo ran la
Alkyl thtourcaa
di-t.-AmylP!,cnol
Antimony potau9iicn>
turtrntc
Carbazole
Chftn, Abi't?.
Registry Nt>.
(WIN)
_
000030466
000304610
(QVYOjqVO-
SB-Od -KA-)
000085743
(T E656 HMJ)
DIM I Taxied-.-, To\Ic K.iAir.l K.iilnr.
Li>:.Q. »'S/k«-. A.-iilu Uiroitlc Toxlcolo.-.v TLV C.ircl!
1S30 orl-rat Probnbly Sono
115 orl-rat L) liiR-3 L)irr-2 USOS aIr:1UA
S)lng-3 ln,;-3 ' 0.5 o.:/ra3 (aa
inl!-3 inh-3 . Sb)
Allergen, toxi- Xono
city unknown
LD30:200 nj/kg
5 Cellulose Waste
6 £-Chlorobcnzcnesul-
fonlc acid
7 4-Chloro-3-nitro-
bcn:ai: acid
8 £-Chloro-«.«:.«-tri-
chlorobenzotrl-
fluorlde)
9 Cyclohexyl alcuhol
10 2,4-Diaainotoluene
11 Dimethylamine
12 £-Dodeeyl aniline
13 Glucose (corn sugar)
14 Rematin
15 Hydrazine
16 3-l!ydrcxybenzenesul-
fonic acid
17 4-Hydroxyienzenesul-
fontc acid
18 p-Hydroxybenzolc acid
19 Logvood extracts
20 Kesityltne
21 Hethanesulconic acid
000103930
(L6TJ AQ)
000095807 '
(ZR CZ D)
000124403
000030212
(ZQ)
000099967
(QVR OQ)
000108678
UR c E)
000075752
:500 mg/kg
orl-rat
698 orl-rat
60 orl-rac
L)irr-l L)U
ing-1 S)U
S)ir.g-2
inh-2
L)irr-2
ing-2
inh-2
S)irr-2
lnh-2
L)U
S)0
L)irr-3
S)ing-3
ing-3
skn
abs-3
L)alr-2
S)ing-3
inh-3
skn
abs-3
3200 orl-rat L)alr-l L)alr-l
S)U S)U
L)t' L)U
S) inh-3 S)JLnh-3
LDLo:200 ng/kg L)irr-3 UU
orl-rat S)Jng-3 S)U
inh-3
148 orl-rat
L)irr-2 L)U
S)lnp.-2 S)a
ing-2
TCLo:10 pp=
TFX.-C.V3 l>.l-;.an
LBLo:2400 ppai/24H
Jhl-rat
LDj0:2.4 Bj/kg
CCTr-(QU3
USOS air: TWA
50 ppa
VKOS air:tva
200 mg/m3
USOS air:r»'A
10 ppm
USOS air:TWA
18 ng/DO
USOS air:TSA
1 ppa
USOS air:WA
1.3 ~''ltru:'enz°yl chloride
25 Oxalic acl.1
000144627
(fJVVp)
l.m.o:1000
orl-dog
kg l.)li-r-l Uirr-3
lng-3 Ji,K-3
lnh-1 Ir.d-J
r;)inr.-3 s)in,--2
USOS nlr:TVA
-------
lT!OCi:::S, WASTE, niltmlCTlON AND USE DATA
h-2
^Sources of
t Compound
Process
No.
V»HtU
Trt-.nmi-nt
To t:il
Hi' forcnccH
3)608
2)119
3)412
2)291
3) Sift
3)543
2)184
2)364
3)17, 591
2)1139
2)440
3)18. 670
2)615
3)19. 814
2)186
2)705
3)20, 902
2)711
3)004
2)245
2)712
3)20. 927
3)964
2)284
3)21. 938
-------
Corapoiiitil Chr'tl. /M'Str.
Item Niitao mill Re£l.slry No.
No. Fjrauln (VI.X)
26 1-Propylaralne
27 Pyrcno 000129000
(1.666 1)6 2A11
PJ)
28 Quebrncho extract 000146485
(Qucbrachliie) (T F6 D5 Cf.65
EM ON i & TTTJ
. TQ UVOl A&Tl!)
29 thlourea 000062566
(ZVZW)
30 Toluene 00010SS33
(1R)
31 o-Toluencsulfonlc acid
32 TrlBolllelc anhydride 000552307
(156 BVOVJ
CVQ)
U-'l
TAi;l>: B-l. (i'..n( iiuioJ)
Or.il To.-. let IV. Tosic l!.r : .it'll R.itin>;
LU.JQ, u«/t>'. Acnli' Cliiinitc
LDLo:.'5 og/kg L)U L)U
orl-ctus S)inr,-3 S)ll
lnh-3
skn
abs-3
20 orl-rat Ulrr-3 1.) t.-.'>-3
lnh-3 S) f:'.!.-2
S)lng-3
lnh-3
5000 orl-rat L)lrr-l L) trr-1
S)inc-2 S) In 3-2
lnh-2 in!t-2
skn 6tn
abs-1 abs-2
L)lrr-3 -L)U
lng-3 S)U
lnh-3
S)lng-3
lnh-3
LD50: 2500 tag/kg
orl-sus
To\(rol.-rv Tl.V Cnrc tiwtt.^H
^
TDLorlO R!r/kB/
3VII, TFX:SKO
skn-ntta
-- TDLo.-lS got/kg/
2YC. TKX:XKO
orl-rat
TCI.o: 2."0 ppn USC5 air: TVM
TFX:C:S ihl-h=n 20C ppm or 750 =g/a2
ICLo: 100 ppm NlCili rec. std.:
TTX.-PSY ihl-nan TWA ISO ppn.
LC50: 5;00 ppn C 200 ppra/lOM
Ihl-cus
-- H . .
«»...».
-------
Sources of Proves
Compounil No,
Associ.ltoJ
Wnst i!.-i
W.HSCC
Tiy.ilin.'nt
Total
l'rtnli:.-t'.on
2)996
3) 1069
2)1204
3)12(3
2)1185
3)1163
3100
(6657.7)-
1974
2)1133
3)22, 1174
3)1175
2)172
-------
r.-5
TABLE 8-2. ORGANIC DYES AMD FIGMENTS. INTEK^JiDIATEE-TUXICITY,
Item
No.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
13
19
20
21
22
23
24
25
26
27
Compound
Nitme and
Fa firm In
Acctamldo, S-(3-antuo-
4-cthoxy phenol)-
Acet.itnldc. N-(4-omino-
phcnyl)-N-n:echyl-
Acotanldu, S-(4-brooo-
9,10-dlhydro-9,10-dioxo-
1-anthracenyl)-
Acvtaalde, 2-chlor»-N-
(4-nltrophenyl)-
Aceeamide, N-(7-hydroxy-
1-naphthaleayl ) -
Acetontde, N-(4-hydroxy-
2-nttrophenyl)-
Acctamide, N-methyl-N-
[4-jj-toluidlno-l-
anthraqulnoayl ] -
Acetamide, H-[2'-nltro-
J'-(7K-benz(de]an:hracon-
7-oneJ-
Acetamida ,S- (7-oxo-7H-
benzt;liv. Toxic H.iir-rd R.utni;
Ll>50. ««/kK ,.fllt. Chronic
..
30 orl-roc
_ _
- ' _
.
800 orl-rat L)ali>l L)alr-l
S)ing-2 S)lnh-2
inh-1 lng-2
1830 orl-rat
3350 orl-rat
_ _
Mild Irritant, low
toxicology
.
_
. ' ^
-. __ .-.
«^. .«. *«
-~ _ _
_ _ ~
LDLoilOOO eg/kg
ipr-mus
, _ .
_' . __
_
Acetanllide, N-2-cyanoeehyl- (See Propioolcrile, 3-(S-acecatilliao)-
Acetanlllde, 2',4'-
dlchloro-
Acetanlltde. 2',5'-
dioathoxy-
Acetanlltda, 2',5'-
dlmethoxy-4 '-alcro-
Ace car.il i
-------
B-6
IVOCKSS. WASTE. raooucTto:! AND VSE DATA
Prov'tfsi In
Sources of Chapter 7* Aacoclatcd Uqsco Totiil
Compound T:ibK'. P.iS«i Process Unites tri-ain-.-nt Production Uses Ref.erohcea
9c, 45 Reduction _____ __ _
2c, 34 . -- 3)349
34c. 71 -- _'.__. _
_ 7d, 39
23b. 51 :
_ 27.63 '
34e, 72 _ _ _ _ _
34c, 70-
_ 34c. 70 _ _- _ _ _ . _
2a, 32
_ 25c, 61 _ '
2a, 32 _ _ . _
25c, 61 '
7d. 39 . 2)9
2a. 32
19, 49
_ 19. 49 .
7e. 40 _ __ _ __ :
27. 63 -- 2)11
2c. 34 '2)11
2e, 34
_ 2a, 32. . . __ _
25c, 61
2a. 32 - - -- . 2)11
7c. 38 2)12
9a. 43 -- . 2)lz
7c. 38 _____
1.591
(3.73)
1974
2)9
3)349
2)9
2)9
-------
B-7
TAHU: tl-2. (Continued)
Item
No.
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
53
Compound
Name nnd
Forrr.tln
o-AcetanlslJlde, 5'-
nltro-
Acetlc acid, [4-(chloro-
»-tolyl-thl«l-
Aceclc acid, (2-naphchyl-
thlo)-
Acetoacecaatlide
Acetoacecanlllde, 2'-
chloro-
Acetoacetanlllde, 4'-
chloro-
Acecoacecanlllde, 4*-
chloro 2* ,5l-dinechoxy-
o-Acetoacetanisidlda
£-Acetoacetophen«tlde
o-Acecoacetocoluidide
£-Acetoacetotoluldlde
o-Acecoacecotululdide,
4'-chloro-
fAcetoacacotululdlde.
4'-nitro-
2* ,4'-Acetoacetoxylidlde
£-Acetophenecide
£-AcecophenaCide, 3'-
Ibis (2-hydroxyethyl) ]
£-AcecopheneCide, 3 ' - [dl
(2-ace toxye thyl) -amlno J -
£-Acetophenetide, 3'-
nitro-
9-AceCoculuidide
£-AcetoCululdlde
£-Acecotuluidlde, 3'-
aclno-
^-Acetotululdide, 4'-
acino
£-Acecocoluldlde , 3'-
Cnloro-
o-Acetotoluldlde, 4'-
chloro-
(K,N-dlechylamlno)-
, £-Acetotoluldlde, 3'-
nltro-
Aalllne derivatives (See
Aniline, 2~bromo-6-
c hloro 4-n 1 c ro-
Anlllno, N-butyl-
Chcn. Abrtcr,
Rffistrv Nc.- Ornl Toxlctcv. Toxic llnr.nr>l Rntlm;
ll.'IN) LBSO' "''''f Aiiitc Cliri-nlc ToxIcoloRv TI.V Cnrclnoiien
033721549 . . -_ _
000094768 - _ _
000093210 -- _ _
000102012 LDI-o:300 mg/kg.lpr- _
(1V1VJE) BUS, weak allergen
000093709 _
000101923 -- -- LDLo:300 ng/kg _ __
(CR DMV1V1) Ipr-r.is
004433798 _ _
000092159 _ _
000122827 _ _
000093685 _ _
002415852 . _ _
020139553 _
_ ' _
000097369 _
000062442 1650 orl-rat L)ing-2 L)U TDLo: 1000 ng/'tg
(ZOR DMV1) inh-1 S)lng-2 TFX:CSS
S)ing-2 lnh-1
inh-1
021615292 _ ' _ _
--. _ _ _
001777840 664 ocl-rat _ _
025449096 1450 orl-nus _
(1VMR B)
000103899 L)D L)U Unknown
S)U S)U
__ _
. - _ _
007149793
005202868
'
002719144 '
also Eenzenomlnc)
'
001126789 1620 orl-rat
(4MR)
Aniline. K-n-bucyt-M(2-
chloroechyl)*-
-------
n-s
In
Sources of
i Compound
| Ui^-
-
__
Chapter 7* Associated Waste Total
Table. P.IRU Process U.istet TrvatMnt Production
7c. 38
28. 63
44. SI _ .
A) 32 - -
7d. 39
9a. 43
19. 49
7c, 38
9c, 45 ~~
4. 64
30. 66
12. 65 ~ '
29b, 65
4. 79 '
9c, 45 ~
Usoa Rc'fort'ncoa
'
2)23
3)350
.
2)28
_ _
"~ * ~
"-
. "
'
"*~ """
_ 2)31
IM^T
9c. 45
9c, 45
9c. 45
29a. 64
30. 66
30, 66
29b, 65
12. 66
29b. 65
29b, 65
30, 66
2)31
2)33
3)353
Reduction
Seduction
12, 45
2b, 33
2b, 33
2)106
-------
It«n
60
61
62
63
64
65
66
67
63
69
70
71
72
73
74
75'
76
77
78
79
80
81
82
83
84
85
86
Compound
K:uui> a tut
Formula
Ant lino, N-butyl-N-(2-
hydroxyechyl)-
Anlllnc, m-ehloro-
Anlllno, op chloro-
Anilinc, j>-chloro-
Anlllne, 4-chloro-2 , 5-
dimechoxy-
Anlllne, S-chloro-2,4-
dlmechoxy-
Aalllne, 2-chlbro-4,6-
dlnltro-
Anlllno, N-(2-
ehlotethyl)-N-ethyl-
ADlllna, H-(2-
cb.loroethyl)-N-aecayl-
Aalllne, 2-chloro-
4-nltro-
Anlline, 2-chloro-
5-nltro-
Anlllne, 4-chloro-2-
nlcro-
Anlllne, 4-ehloro-3-
nlcro
Aniline, 2,6-dlbromo-
*-nlcro-
Anlllne, 2,4-dichloro-
Anillae, 2,5-dlchloro-
' Aniline, 3,4-dicaloro-
Anlllne, 2,6-dichloro-
4-nitro-
Anlline. 2,5-diethoxy
Anlllne, N.tf-diechyl-
Anlllna, N-N-diechyl-£-
nicroso-
Aalllne, 2,5-dl^ethoxy-
Anlllne, 2,5-dl=ethoxy-
4-nltro-
Anlllne, N.H-dlaethyl-
Anlline, M.N-dlaethyl-
Pj-nleroso-
Anlllne, 2,4-dialcro-
Anlllne, N-eChyl-
Chcm. Abitr,
RcRlatry No,
TABLE
Or.il Toxtclty,
_ 11-9
H-2. (Continued)
Toxic llflznrd K.itlnt:
Acttto Clirouic
- ' ' *
Toxlcolocv TLV Cxrrlno^c^^ft
^-
(S«e Ethanol, 2-lN-n-butylanillno)-
000108429 .
(ZR CC)
000095512
(ZR BC)
000106478
(ZR DC)
006358641
(10R BZ EG D01)
000097507
003531199
000092499
001669853
000121879
(ZR BC DSW)
006283256
000036634
(ZR DC BNUZR DC
000635223
OOOS2741I
(ZR DC CNU)
000554007
(ZR 3G DC)
000095329
000095761
(ZR CC DC)
006627345
(ZR BC FC DNW)
000094859
000091667
000120229
000102567
(103 BZ 001)
006313377
000121697
(lid iH)
000138896
(im UNI 41>
000097029
(W1IR BZ E.NW)
000103695
880 orl-rat
256 orl-aus
300 orl-rae
100 orl-bdu
BNK)
100 orl-bdw
LDLo:157 mg/kg
orl-cac
643 orl-rac
1500 orl-rat
--
100 orl-bdw
LDLo:1410 Eg/kg
orl-rat
65 orl-rat
418 orl-rat
«
"
-T*
.
'
UDU-.310 mg/kg
scu-cac
LDLo:310 ns/kg
scu-cac
TCLo:44 ng/a _
Ihl-hmn TFX:BLD
_ _ _
IDLo: 503 mg/kg
Ipr-mu3
LD50:63 og/kg . . _
Ivn-nus
' '
_ _ _
_ _
TCLo: 25 ug/n
Ihl-han TFX:EYE --
LDLorlSOO mg/kg
orl-rat
_ _
_ _ _
--
' .
LD50-' I?" og/ks BSOS alc:TWA
skn-rbt 5 ppa (skn)
TDLo:7300 mg/kg/
: It, TFX-.NEO.
orl-rat
LDLo: 250 og/kg
Ipr-rac ' '
_
87 Aniline. S-eehyl-N- (See Ethanol, Z-(N-ethylaolllno)-
(2-hydroxyoth/l)-
88 Aniline, M-(2- (See Ethanol, 2-(N-mechylantUno)-
hydroxyetliyl)-H-ncthyl-
-------
fl-10
Sources of
Comivurut
^
Proci'3.4 In
Ch.ipcer 7*
Table. Pa«« Pi-noes*
25b, 60
45. 39
9a, 43
19. 49
40, 79
12. 40
2b, 33
6. 34
7d, 39
7e. 40
9c, 45
18, 43
7e. 40
9a, 43
12. 32
2a, 32 '
2Sb. 60
45, 48
9e. 45
12, 45
19. 49
6,8,10, 33
2b, 33
20, 49
19, 49
6,7,8, 34
10
2c, 34
7e, 40
2b, 33
A«»oclnccd Waste Total
Wust.'s Trr.itmi.-nc Production Usos References
_ 2)106
_ _ ' 2)106
_ _ 2)106
_ _ 2)106
_
_ _ _
_ _ _ _
_ _ "
_ 2)106
_ _
__ _ _ 2)106
__ _ _ » ~~
_ _ 2)107
' _
' _ 2)107
_ _ 2)107
_
_ 1.495 (3.295)-1974
« » « ~*
_ _ 2)107
.- _ - .
8.803 (19.407)- 2)107
1974
_ _- _ 2)108
_ 0.261 (0.577)- 2)109
1974
1.088 (2.399)-
1974
-------
B-ll
TAIILE B-2. (Continued)
Itea
So.
89
90
91
92
93
94
95
96
97
93
99
100
101
102
103
104
10J
106
107
108
109
110
111
112
113
1L4
115
Compound
Kdtne and
F.Ttmilll
Aniline. 2-hydroxy-
J-mathyl-
Anlltne. 2-oethoxy-
J-methyl-
Anlllne, 2-oethoxy-
6-n«Chyl-
Anillne. 4-mothoxy-
-3-nltro-H-phcnyl-
Anillae, N-aethyl-
Anlllne, 4.4'-
oethylenibts-CN.S-
diethyl-
Aolllne. 4,4'-
oethylenibls-[N,N-
dlmethyl-
Anllina, cj-nltro-
Anlline, o-nltro-
Anlliae, £-nitro-
Aalllne sulfcnlc acid.
ecbylbeuyl
Aniline. 2,4,5-
trlchloro-
o-Anlslc acid
£-Aalslc acid
c-Aolsidloe
o-Anlsldine
2-Anlsldlne
o^Anlsldlne,- 4-nr (See
bucylaulfonaaldo-
£-Anialdiae, 4-chloro
o^Anlaidiae, 5-chloro-
£-j\nlsldlae, 2-nltro-
^-Anlaldtne. 3-nlcro-
tt-AnUidine, 4-nlcro-
o-Antsldlae, 5-nltro-
o-Antsidlne, 5-nlCro-
H-cthyl-
£-i\nt»ldl.ic, 3-nltro-
N-phenyl-
Clmm. Ahstr.
(ULN)
001207131
050363730
000100618
(1MR)
000135911
028213812
UNUR n- 2n
000099092
(za GNU)
OOOOSS744
(za BMW)
000100016
(za DKU)
Or.-il ToxUlty,
'
tDLo:2SO og/kg
orl-rbt
631 orl-rac
535 ocl-rat
535 orl-rat
3249 orl-rat
Toxtc Ihirnr.l Rntim1. ^^
Acuto Chronic Tnxlcolo^v TLV Carclnovie^^l
- -
. _*
«.«.-
"
-- USOS alr:TVA
2 DPO (skn)
_
_
LDLo:70 og/kg - .
Ipr-dog
LDLo: 40 mg/kg USOS alr:TWA
ivn-nam 1 ppm (skn)
(See n-Toluenesulfooic acid, «e -(N-ethylanillno)-)
000636306
000579759
000100094
000536903
000090040
000104949
(za DOI)
Senzenesulfonamide
000093505
000095034
000096963
000577720
000097529
000099592
(VWR CZ DO'.)
Anlsole, 4-onlllno-2-nltro- (Sec Aniline,
1400 orl-rac
v_ V ' ~ "
Unknown -- "~
probably low
Unknown "~
probably low
_ _
L)lrr-2 L)lrr-2 osos «lr:WA _
alr-1 alr-1 "-1 «>» Cskn>
lng-2 S)lng-3 "S05 «lr:TWA
S)ing-3 lnh-3 . °-5 °K'°3 (skn)
lnh-3 skn
skn abs-3
abs-3
L)irr-2 L)lrr-2 USOS alr:T«A
alr-1 alr-1 0.1 ppta (skn)
lng-2 S)ing-3 USOS alr:TWA
S)lng-3 lnh-3 0.5 mg/o3(skn)
lnh-3 skn
skn aba-3
abs-3
, 3-aaino-N-|i-butyl-4-methoxy-)
-
704 ocl-rat
_ _ '
_
1
--
_
~
_ .
4-methoxy-3-nIcro-!l-phenyl-)
-------
1'rofOMn In
Sour co L; of
Ct'r.lIVltlKl
_
Cli.'ipC
lull 1 1- ,
15.
15.
14.
18.
2c,
t:r 7* AM^OC lat i-J Wiistc Total
, I'iir.o Procoss W.-isu-;; TnMtruMU rriuhict li'n Ust*3 Kef nviw»-s
47 Reduction
47 Reduction
47 Reduction -- ~ --
4S --
34 ~ 2)110
6,7, 33 '
2c, 34 O.SA4 (1.S62)- 2)110
1974
25c, 61 ' 2)111
2a, 32 Egjsston factors: MHj - 3.0, ~ 2)111
7d, 39 nitrobenzene - 1.0, KO- - 1.0, 12)
SO - 1.0
2a, 32 Enissicn factors: saac as . 2)111
9c, 45 o-nitoiniline ' 12)
40. 79 ~ --
36, 76 -- 3)410
21. 50 ~ 3)410
25e, 61
7c, 33 . _ _ 2)113
3)410. 15.
9a, 43 2)113
3)410, 16
25b, 60 ______ __
18, 48
9a, 43 -- --
7c, 38 ' '
7c, 38 _ _ ... 2)113
7e, 40
18, 48 -- '
-------
u-u
TAIUJ: B-2. (ContlniuMl)
Item
No.
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
Compound
Kama And
Fomula
Clicm. Abatr.
Registry tlo, Orul Toxiclty, Toxic lin:nr>t Rnrlm;
(WIN) LU50- "«/k^ Acute Cl.ronlc Toxlcolocv
Anlsole, S-ti- (Soe Bunzenesulfontuildc, (l-£-bucyl-4-mechoxy-3-nlcro)
buty Isul fonnnido-i-
nltroanlsole-
Anlsole, 4-chloro-2-
nltro-
Anlsolo, 2,4-diamino-
Anlsole, 4,5-dichloro-
2-niiro-
Anisole, 2,4-dinlcro-
Anisole, «r-nechyl-
Anisole, £-nicro-
Anlsole, -Anisoyl chloride
£-Anisoyl chloride,
3-nitro-
2-Ancbraceaecarboxylic
acid, 3-chloro-
2-Anchracenecarboxyllc
acid, 3-chloro-9,10-
dihydro-9,10-dioxo-
2-AnChracen«carboxylic
acid, 3-hydroxy-
9 , 10-Anthracenedione
9,10-Anchracenedione,
1-anino
9 ,10-Ancbracenediooe ,
2 amino
9 , 10-Anchracanedione ,
l-amlno-2-bronio-4-
^toluidlno-
9 ,10-Anchraceaedione,
l-amiao-2-chloro
9,10-Aachracenedione ,
l-amlno-5-chloro -*
9,10-Anchracenedione,
l-amino-8-chloro-
9,10-Anchracenedlone,
2-aoiQo-3-chloro-
9 ,10-Anchracencdlone ,
l-amlno-2-chloro-4-
hydroxy-
9,10-Anthracenedlone,
l-aoino-2,4-dibro=o-
9,10-Anchrncencdlone*
2-amlno-l,3-dichloro-
9,10-Anchracenedlone,
l-aolno-2,4-dlchloro-
9 , 10-Anthracencd lone ,
l-oolao-2 ,4-dlhydroxy-
9.lO-Anchrac£ncdionu,
000089214 -_
(See o-phenylcn:100
(VWR B01 EN-.V) orl-rac
000100845 .
000555033
000091236
000100174 4700 orl-oao
000100072 L)lrr-3 L)U
ing-3 S)U
inh-3
S)U
010397281
000135477
_ .. ^_
006295449
. »
000084651 ' '
(L C666 BV IVJ)
000082451
(t C666 BV IVJ D2)
000117793
034037462
000117077
000117113
000117099
000084463
002478673 .
000081492 _ _
006374761
013432321 .
000081516
000117771
TLV Cure
--
*
'
~
TDU>: 90
'TFX:SEO o
TDU>:2440
TFX:8EO
~~
"
'
-------
B-K
Process In
Sources of Chnptcr 7*
CompxMm.lTable. P:iau
Tot«l
Product ton
IS, 48
25b. 60
7e. 40
14, 47
25c, 61
7c, 38
9a, 43
21, 50
2)167
3)410
23a, 50
34b, 69
34b, 69
34b, 69
34g. 74
34e. 63
34c, 70
34e, 72
28, 74
15,28, 75
34a, 68
28, 71
34, 71
28, 68
34b. 75
12, 75
12. 74
12, 75
28, 74
36, 68
0.318 (0.702)-
1974
2)116
2)116
0.389 (0.857)-
1974
-------
TABLE I1-2. (CjntlnneU)
Ucm
So.
144
143
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
Compound
N-irac and
Formula
9, 10-Ant!ir acened tone ,
l-smlno-2-Bothyl-
9,10-AntNruccnedlaae ,
1-amlno-i-ntcro-
9 , 10- Anthracenetl lone ,
l-ootno-5-nitro-
9,10-Anthraccnedione,
1-brooio-
9,10~Anthraccnedloae,
1-bvooo-H-hydroxy-
9,10-AnChtaceaedlana,
l-bromo-A-ce thylaiaino-
9,10-Anchracenedione,
1-chloro-
9 ,10-Anthracenedlone ,
2-chloto-
9 ,10-AnchraceneJione ,
l-chloro-4-hydroxy-
9,10-Anchracenedioae,
l-chloro-2-oechyl-
9»10-Anchracenedioaa,
l-chloro-4-aitro-
9l10~Ancaraeenedioae,
l-chloro-5-nicro-
9 , 10-Anthracenedione ,
l-chloro-8-nicro-
9,10-Anc'dracenedlooe,
l,5-diactn»-
9,10-Aotaraceaedione,
1,8-dianlno-
9 , 10-Anthracenediooe ,
l,5-dtaElno-4,8-
dihydroxy-
9 ,10*Anchracenedione f
1,2-dlchloco-
9,10-Anthracenedione,
1,5-dichloro-
9 , 10- Anthracenedloae ,
1,8-dichloro-
9,10-Antbracenedioaa,
2,3-dlchloto-
9 , 10-AnChracenedione ,
1,2-dihydroxy-
9 , 10-Anthracenediooe ,
1,5-dthydroxy-
9,10- Anchcacened lone,
1,8-dlhydroxy-
9 tlO-Anchracenedione
2,6-diliydroxy-
9 , 10-Anchracenedione ,
1.5-dlhydroxy-4.8-
dlnltro-
9,10-Anthcaccnedlone,
1,5-dlmechoxy-
9 , 10-Anlhrnccncdlono t
Chem, AbaCT.
Koflscrv No. OiMl Toxlclty. Toxic l!.:znrJ Rnttn^
(WLN1 u'50' "*/l'S Acin.- Clirop.lc Toxtcoloitv TLV
OOOOS2280
005937742 . _ _
_ _
000532837
. _- _
000128938 --
000082440 .
000131099
000032428 .
000129351 '
006337322
000129408
000129334
000129442
000129420
000145433 LDLo:256 tcg/kg
(L C666 BV IVJ DZ ipr-ous
CO KZ SO)..
001594463 ~
000082462
000082439 --
000034457
000072480 ' .
000117124
000117102 LDLO-.500 ng/kg
-------
B-16
Process In
Sources of Clmptsr 7*
Compound Table. I*;KL- Process
34b, 69
28, 72.75
28, 70
34e. 72
12, 73
12, 72
28. 72
28, 74
12. 73
25. 69
34e, 72
34d, 71
34d, 71
28,32, 70,71
34c. 70
' 344, 71
34a, 68
34d, 71
34d, 71
34a, 68
23, 74
33,15, 74,71
34d, 71
- 34g, 74 ~
34d. 71
34d, 71
34d, 71
AsaoclntuJ
Unites
-
Waste Total
Treatment Production
.
.
_
_
_ _
_
_
.-
-.
_ _
_
_ _
_ _
_
_
Uses References
_ .
_
_-
.
_ _
_ _
-_ _
.
_ _
2)115
_ _
'
. 2)116
_- _
_
. '
'
-------
B-17
TAlilJi tl-:. (conclniud)
I tea
No.
171
172
173
174
175
176
177
178
179
ISO
181
182
183
184
185
136
Con pound
Nnmo and
Fornul.i
9 , 10-Aachraccncd lone ,
1,5-Jlnlcro-
9 » 10-Anth raccnedione ,
1,8-dlnltro-
9,10-Anthracenedlone,
1,5-dlphenoxy-
9 , 10-Anth raccnedione ,
l-hydrazlno-2-oethyl-
9,10-Anthracenedlone,
1-hydroxy-
9 ,10-Anthracenedlone,
l-hydroxy-4-nttro-
9,10-Anthracenedlone,
1-nethoxy-
9,10-Anthracenedione,
Z.methyl-
9 ,10-Anchracenedione,
1-aethylaaino-
9,10-Anthracenedione,
1- (aethylamlno ) -4-
[ (4-nethylphanyl) asiiao ] -
9 , 10-Anth racenedloae ,
2-Be thy 1-1-nl t ro-
9 , 10-Anthracenedlooe ,
1-nltro-
9,10-Anthracenedione,
1,4,5,8-tetrachloro- .
9 ,10-Anthracenedione ,
l-(4-tolysulfoaamido)-
2-chloro-
9 , 10-Anchracenedlone ,
1,2,4-trlhydroxy-
1,5-Anthracenedlsulfonic
Chen. Ab.ur.
Rustatry No. Ornl ToxUU'v. Toxtc llnrnnl Rntliu;
(WLN) LU50> n'*>'k« A«-uto Cliuinlc Toxicolo
-------
B- in-
Process in
Sources oC
CoropounJ
-
Chnptcr 7* Associated Wnsce . Total
TubU', l*.i);e Process Unsloti Tn-ntnu-nt Production U.«os
28, 70
34c, 70
34d. 71
34b, 69
34f, 73
34f, 73 _
34e. 72 "
34b, 69
28, 72
28. 72
34b, 69
34c. 70
. 12.39. 70 ' .
34a. 68 ~
34g, 74
15, 71 Sulfonaclon
ReftTcnceo
.
15. 71
33. 71
74.
33, 71
15. 74
33, 71
74
15, 74
3Ac 70 _ 0.518 (1.142)-
1974
34d, 71
34d. 71
-------
B-19
TAUI>: li-2. (Continued)
1C cm
So.
Compound
Name and
F.-rrailrt
Clicm. Abstr.
RoRlstry No.
(WLN)
Or.tl Toxiclty,
l°M- "6'^
tar.lf llninril R/utni;
Acutr Chronic
Toxlcolor.s-
TLV
Cnrctnoi
2-Anthnui-neaulfonlc 015100535
acid
2-Anlhra.:cr...-suUonlc 000128994
acid. l-a:ntno-4-O-
amlno-4 -suit o-anl lino) -
9 . 10-d thydro-9 , 10-dloxo-
2-Anthra.-encsul£onlc 000031696
acid, l-.imino-4-(4-
aailno-3-*ulfo-anlllno)-
9,10-dlhydto-9.10-dloxo-
Z-Anthraceneaulfanlc 000116S14
acid, l-jnlno-4-bromo-
9,10-dlhvdro-9,10-dloxo-
2-Anchracen«3ulfonlc OOOOS3625
acid, l-iaino-9.10-
dlhydroi-9 ,10-dloxo-
2-Anchracenesulfonlc 033016692
acid, 3-jailno-9,10-
dlhydro-9 , 10-dioxo*
2-Anchracen*sul£onle
acid, l-aolno-9,10-
dlhydro-i-(3-nitco-4-
Eulfoanilino)-9,10-
dloxo-
2-Anthracenisul tonic
acid, l-amlno-9,10-
dlhydro-4-(H-nitro-
3-sulfoaailino)-9,10-
dioxo-
2-Anthra^eaesulfcnic 00084480
acid, 9,10-dihydro-
9,10-dloxo-
2-Anthracenol 000613149
Anthranillc acid,
B-(4-aolao-l-
anchraqulnoayl)-
Anthranillc acid,
H-[ (3-carboxy-4-
chlorobeazene)'
sulfonyl]
Anchranilic acid, 000612420
n-carboxy cachyl-
Anthranillc acid. 000039770
4-chloro-
Anthranilic acid, 000119686
H-nethyl
Anthranilic acid,
S-(4-nltro-l-
aachraquinonyl ) -
Anthranillc acid, 000098431
4-sulfo
Anthronillc acid, 025352276
5-sul£o-
Anthraqulnone, 1- ~
acetaotco-4-broao-
K-methyl-
Anthrnqutncnc. 1-
acetamlio-!i-mcthyl-4-
195
196
197
198
199
200
201
202
203
204
205
206
207
203
209
210
211
212
213
214
215 Anthraqutnonc, 1-natno-
4-antlir.o-2-brooo-
216 Anthcn^'itaono, 2-atnlno-
l-brorao-3-chloro-
-------
B-30
Proroda in
Sources of Chapter 7*
Compound Table, Pago Prci'ma.
Waste
Treatment
Total
Production
Uses
RofcftfflCua
34g. 74
34h, 75
34h, 75
12. 75
15. 75
15. 74
34h, 75
34h. 75
34c. 70
34g. 74
34e, 72 Reducclon
10. 46
5. 35 -
29b, 65
5. 35
28. 72
38, 77
5, 35 -
34c. 72
34e, 72
28, 75
34*, 68
-------
Iten
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
Compound
Name and
ro rail In ^_
AnCliraqutnone , 2-
»olno-l , 3-d Ib raaj-
Anchraqulnone, 1,5-
bls(dlnUrophenoxy)-
4,8-dlnltco-
Anchroqulnoae, 1- (Sc«
hydrazinj-2-inethyl
Anchrnquinone, 1,4,
5,8-tetrjhy-
[ (2-chlo roe chyl ) -
nechylacioo]-
Benzaldehyde, 4-
[(2-chloroechyl)
echylanino)
Benzaldehyda , ^~
(dieehylanino)
Benzaldchyde, g-
dlaechylaolno
Benzaldehyde, o-
nltro-
Benzaldehyde, £-
oicro-
Benzaroitie, N-(4-anino-
1-anchraqutnonyl)
Benzamlde, N-(4-aaino-
B-.'l
TAB IK 11-2. (Continued)
Clicm. Abstr.
Rcslstry No. Ornl Toxlqtty, Toxic llnzurri Rntln^
(VLN) 1.1)50, ms/Ks 'Ac.it.! Chrunlc' Toxicology
_ _
-
9,10-Aathracenedlone, l-hyilrazinc-2-methylr)
000031607 ~
0001:8676 tDto:2300 ma/kg --
(L C666 BV orl-rac
IV J Bffl EVQ)
000529862 ~
001830779
_ _ _
000103333 1000 orl-rac L)U L)U LDLo-50 mst/kz
(RNinm) S)iog-2 S)lng-l "^ 8/ *
ioh-2
000493487 620 orl-rat L)U L)U Liaitad animal ex-
-
1-anthricenyl)-
237 Benzamide, N-(5-amino- 000117056
9,10-di->ydro-9,10-dloxo-
1-anchracenyl)-
238 Benzatnide, 4-anino ~
N-echyl-N-1-naphchyl-
239 Benzaaide, j>-nntno-N-
(7-(4-h/droxy-2-
naplithalenestulfonlc acid)]
240 BenznmHe. 3-onino-4- 017481275
nechoxy-
241 BenxaraHe. N-(4-n.-3ino-
5-raotho:cy-2-cieiiiylphonyl)-
-------
Process In
Sources of Chapter 7*
Compound Tubli-. Pai;e
Assoclncod
Wnstes
Wnate
.Trvntnu'nc
Total
Product ton
Uaoa
Rufcrcnces
12. 74
34d. 71
34g, 74
34b, 69
2)117
26, 70
29a. 64
34g. 74
34b, 69
34b, 69
25a. 59
2)138
3)427
25a. 59
2)140
3)428
9. 33
6, 78
9, 34
2)154
2b. 33
6,3. 33
2c, 34
5. 35
30, 66
37, 75
37, 75
72
Reduction
0.007 (0.015)-
1974
2)154
2)155
0.019 (0.043)-
1974
34c, 70
23a, 50
5, 35
231. 58
Reduction
21, 50
29!>. 65
-------
B-23
TAIILK B-2. (Continued)
I tea
Compound
N;inK* nnil
-Formula
Chen. AbsCr*
Registry No.
Oral To.xK'tty, Toxic H.iziml S.ictoi;
LU50. mn/ks Ac.ito Chronic
242 B*nzamtd«, N-l-
anthraqulnonyl-
243 BenzanlJe. N-(5-
«athrau s>u ior-nus
Q IVJ
013456809 --
050607200
7-onc, 3-ao»ino-2-nlCro-
267 7H-Bcnz(dclanchraccn-
7-onc, 3-bcnzoyl-
268 7ll-Bcn:[.Jc]anclirnccn-
7-one, 3-bromo-
000081969
-------
B-24
Process in
ea ol Diopter 7* Asaoelntcd Waste Total
Mund Tiiblo. Pay,c Proceaa Wn»t»'B Tronttr.i'n; Production V»rs Reference
12,31, 75 _
3/ic. 70 ' -- .
12. 46
12, 72 Chlorinacloa
75
34e, 72
34h, 75
23a. 50
23c, 52 '
29b, 65 ~
21. 50 .
25c, 61
231. 58
9c. 45
19. 49
19, 49 '
25c, 61 Reduction
25c, 61 .
20, 49 --
20, 49
20, 49 --
^
20, 49
25c. 61
.9C( 45 _ _ _ _ _ _
26, 70 0.330 (0.838)- 2)161
1974 . . 3)440
34c, 70
34c, 70 '
26, 70
12,34, 70 0.380 (0.838)-
1974
-------
E-25
TAHIJ-: U-2. (Continued)
Icea
No,
269
270
271
272
273
274
275
276
277
278
279
280
281
232
283
284
285
286
287
238
239
290
_291
292
293
294
295
296
Compound
Ndrco and
7H-Bonztdo]unthcaccn-
7-one, 3-chloco-
7H-Ben7: (de)nnthraccn-
7-onc, 3,9-dlbrooo-
7H-Benz[de]anthracen-
7-one, 3,9-dlchloro-
7K-8enz [ d* ] an thracen-
7-one, 2-hydroxy-
7K-Benz[d«lanthracen-
7-one, 2-iathoxy
Benzemimlne derivatives,
Benzene, l-chloro-2,4-
dlse thoxy-5-ni t co-
Benzene, l-chloro-2,5-
dlmethoxy-4-nitro-
Beazene, l-chloro-2,4-
dinitro-
Benzene, l-chloro-2-
nltio-
Benzene, 1-chlorc 3-
nitro-
Benzene, l-chloro-4-
nltro-
Benzene, tj-dichloro-
Beazene, 1,2-dichloro-
4-ae thoxy-5-ni t ro-
Beazene, 1,2-dichloro-
4-nitro-
Beazeae, 1,4-dichloro-
Beazene, 2,4-dicnloro-
1-nltro-
Beazene, ^-dlechoxy-
Beazene, 1,4-diethoxy-
2-aitro-
Beazeae, £-dlmethoxy-
Benzene, 1,4-dimethoxy-
2-nltro-
Benzene, 2,4-dlmethyl-
1-nltro-
Benzene, &-dinlcro
£-Benzenedlsulfonlc
acid, 2-aalno-
1,3-Benzenedlsulfonic
acid, 5-aalno-4-hydroxy-
1,3-Benzenedlsulfonlc
acid, 4,5-dlantino-
m-Bcnr.enedlsul Conic
acid, 4-fornyl-
H-P-enzcncdlsulfonlc
Chom, Abatr.
RcRlstrv No. Oral Toxlclty. Toxlr Huznril RutlciK
(WUN) .L1>50- °*'^ Acuco Ctironlc Toxlcolosv TLV
006409445 ___
000081981
. _
_
006535677
(See Aniline derivatives)
000119211 -- _ '
006940530 .
000097007 1070 orl-rat
(WNS 8G ESW)
000088733 288 orl-rat
000121733 -- TCLo:12 ug/m3
TFX:eye, Ihl-htnn
000100005 1414 orl-nus . CSOS alr:T.'A
(HNR DC) '1 DK/n3(sta)
000541731
_ ' '_ _
000099547
000089612
000611063 -- ~ .
000122952
000150787 LDLo:300 r.g/kg
(10R D01) ipr-mus
LD50:1133 mg/kg
lor- rat
000089394
t
000039872
000099650 42 orl-bdw USOS air:TCA
(WNR CNW) LDLo:29 ng/kg 1 0«/n1fskn>
orl-cat
000098442
000120939
000137508
000038391
000096775
Cnrcti
--
_
. _-
acid. 4-hydroxy-
297 1,1-Bcnzpn-jdiaulfonlc
octd, 4-'iiy-lruxy-5-nltro-
n tc
aclrt, 2-nltro-
000119006
-------
Process In
Sources of
Compound
.
'
Chapter 7* Auuociaced Waste Total
Table, Paije Prptcss Wnsti-s Trcntmfnt Production
12. 70 "
12. 70
12. 70
34c, 70 -- --
34c. 70 ~
40. 79 '
19, 49
3, 36
7a. 36
25a. 59
7a. 36 .
25b, 60
40. 79 . .
12. 45 -
18, 48
25b, 60
19, 49
20, 49
I'scs Reference!
_ _
_ _
.
_ _
. 2)165
2)165
. .
2)165
_ _
'
19, 49
2)166
19, 49
42. 79
25c. 61
8a, 41
32, 67
15. 61
11. 77
32, 67
32, 67
8a, 41
2)166
-------
TAIILK 11-2. (Cunt I nurd)
Item
No.
Compound
Njao ami
Forrmln
Chora. Ab*tr.
Registry No.
Or;il Toiltjlty, T-'xlc H.'ir.nr
*-pjQ» "yt'S Acme C
Toxicology
TLV
Curclnogc
299 BeozenoHuUlnlc acid, 000100038
_£-chloro-
300 Bcnzenesulfinlc acid,
2-clilo ro-5-n 11 ro-
301 Bonieaesul5onamlJc, 3-
o=ino-N-ti-butyl-4-
oechoxy-
302 Benzcnesulfonoalde. 05229S449
4'-aolno-:',S'-
dlaechoxy-S'-phenyl-
303 Benzeneoulfonanida. 3- 000030239
aaino-4-hyJroxy-S-
nethyl-
304 B^nzenesulfonaolde,
N-S-butyl-4-nethoxy-
3-nicro-
305 Benzenesolfonamlda, 000093646
E-chloro- (ZSWR DC)
306 Benrenegultonamida, 000137473
4-chloro-S-N-dimechyl-
3-aitro-
307 Benzenesulfonamide, " 000137484
4-chloro-X-aethyl-3-
ottro-
303
309
310
311
312
313
314
315
316
317
318
319
320
321
322
BeazcnesulfonaaJ.de,
A-chloro-3-nltro-
Benzenesulf onaolde ,
N- (2 ,5-d lcethoxy-4-
nlcro pheayl)-
Benzenesulfoaamide,
N-(2,5-dl34thoxyphenyl)-
Benzcnesulfonacvide, 4-
hydroxy-S-=ethyl-3-nltro-
Benzenesulf onanillde ,
2-aalno-X-ethyl-5-
nltro-
Bentcneaulfonanillde,
4-chloro-3-nitro-
Beazenesulfonate, 8-
aalno-3-, 5-disulfo-l-
naphchyl-
Benzenesulfonlc acid,
3-acecyla=lao-
Benzenesulfonlc acid,
5-(acetylialno)-2-amino-
Beozenesulfonic acid,
S-acetamido-2-amlno-4-
»ethoxy-
Bengenesulfonic acid,
o-amlno-(cetanHic acid)
Benzenesulfonic acid,
2-amino(orchanilic acid)
Benzenesulfonic acid,
5-amlno-2[4-(a!ninophenyl)
oaino J-
Benzeneaulfontc acid,
5-antno-2-aollino
Bcn/.eneHulfonic acid.
000097096
034233374
000137495
~
000096786
000121471
000083211
000119700
000091305
014846083
LDLo:500 tug/kg
orl-rat
2-(£-amino-anilino)-5-
nicro-
323
Bcnzeneaulfontc acid,
029452720
-------
B-2H
Vroci-srt In
Sourcoa of Umit:er 7* AsnoclnteJ Woetc Totol
ComivunU _ Table. i':i>;u _ Process _ Wnsto-s _ Trvntr:cat _ Product ton
7a, 35 .
9a, 43 ~
8a, 41 Reduction
20. 49
26. 62
8a. 41
7a. 36
7b, 37
7b, 37
7b 37 _ 0.367 (0.808)-
' 1974
20, 49 . .
20, 49
26, 62 " ~
9b, 44 ~
7b. 37 ~
23c. 32
25a, 59
9b, 44 ~
8b, 42
. ,. .. _ 0.591 (1.304)-
7o, 37
5 . 35
9b. 44
20, 44
20. 44
25s. 61
-------
II-2-)
TAHU: B-2. (Cdiillnuvd)
Item
Com|>ound
N:itiul and
Formula
Chen. Abstr,
ROKlacry No.
Oral Toxlijlty,
Tonic llarurd' Sating
Aenctf Clir.-nit:
ToxU-oloRy
TtV
324 BenienesulfonLc ncld. 004953323
2-( (4-amlno-3-bro:no-9,
10-dlliydr»-9.10-dloxo-
1-anchracenyl)nalno-5-
eethyl-
32S BenrenesulEonlc acid. 000133744
2-«mtno-5-chlo co-
326 BenzenesuUonlc acid, Q0009S362
3-amlno-4-chloro-
327 Benzenesulfonlc acid, -~.
4-amlno-2-chloro-5-
hydroxy-
323 BeniencsuUonIc acid, 002706287
2-amino-i1,5-(dlazo)
di-, disodtun sale
329
330
331
332
333
334
335
336
337
338
339
Beozenesulfonlc acid,
2-anino-4,5-dichloro-
Beazenesulfonic acid,
3-amino-4-hydroxy-
Beozenesulfoaic acid,
3-aninc2-hydroxy-5-
nitro-
Benzenesulfonlc acid,
2-amino-5-mechoxy-
Benzenesulfonlc acid,
3-aoino-4-me choxy-
Benzenesulfonlc acid,
5-anino-4-siechoxy-2-
nicro
Benzenesulfonlc acid,
2-amino-5-nitro-
Benzenesulfonic acid,
A-atoino-2-ni t ro-
Benzenesulfonic acid,
j-((p-aninophenyl)azo]-
Beazenesulfonic acid,
Benzenesulfonic acid, (S<
000098373
^
013244332
000093420
"^
000096753
000712243
000104234
>e Beazenesi
3-(amino-4-cosyl)-4-
oethoxy-
340 Benzenesulfonlc acid, ' 000088357
2-anilino»5-nicro-
341 Benzenesulfonic acid,
2-£-anisidino-5-oitro-
342 Benzenesulfonic acid,
4-chloco-3,5-dlataino-
343 Benzenesulfonlc acid, 004515268
2-chloro3,5-dinltro-
344 Benzenesulfonic acid,
3-chloro-4,6-dlnicro-
345 Benzenesulfonlc acid. 038185067
4-chloro-3,5-dSnitco-
346 Benzenesulfonlc acid,
4-chloro-3-hydrazlno-
347 Benzenesulfonlc acid,
5-chloro-2-hydrazlno-
"348 Benzcncsulfonlc acid. 006973133
5-chloro-4-mcthyl-2-
nlero-
1640 orl-rac
-------
fl-30
Process In
Sourci-» of Chapter 7* Associated Wostc Toinl
'.Compound Tal'K*. I'-TKC Pivo.-sa Unati-3 Tn-atracnt Production !).<>» Reference*
34h, 75
9a, 43
8a,. 41 Reduction
15. 43
4. 32
17, 47 Reduction
6a, 41 ~
9b, 44 Partial
Reduction
15. 43 "
7c, 38
7c. 38
3b, 42
9b,44
25c. 61
4 32 _ _ 0.197 (0.434)- 13
1974
9b, 44 Reduction
3. 44 " -
3. 44
8a, 41 Reduction
9b. 44 -
12, 40
4, 41
4. 41 -
4, 43 Reduction
39. 78 --
-------
II-JI
TM1I.K H-2. (Contlnucil)
Item
No,
Compound
Namo itnd
EVrrui In
Chcu. Abstr.
Registry No.
Oral Toxiclty.
'
Toslc llnznnl S;u_tni!
AcuU' Clir.-nlc
Toxtcolot'.'
349 Beusencsulfonlc acid,
£-cliloro-3-(3-tm.'thyl-
S-oxo-2-ry r«zo1ln-1-
yl)-
3SO EenzcncsuLConlc acid,
jf.cliloro-6- (3-methyl-5-
oxo-2-pyraiOlln-l-yl)-
351
352
353
354
355
356
357
BenzcneauLfonic acid,
4-chloro-3-nltco-
BcnzcncsuUonic acid,
2-chlo ro-5-nl t ro-
Benzenesulfonic acid,
2,4-dlaalno~
Eenzenesulfonlc acid,
2,5-dlanino-
Benzenesulfonic acid,
2 ,5-dlaoino-4-niethoxy-
Bcazenesulfanlc acid,
3,4-dlchloco-
Bcnzenesulfonic acid,
2,5-dlchloro-4-
000121186
000096731
OOOOS3631
000038459
000939957
hydrazlno-
353 Beazenesulfonic acid, 000084571
2,5-dlchloro-4-(3-nechyl-
5-oxc 2-pyrazolin-l-yl)-
359 Benzenesulfonic acid,
4,5-dlchloro-2-nlcro-
360 Benienesulfonlc acid, 00008902JL
2,4-diaicro-
361 Benienesulfonlc acid, .
3 , 5-dlnlc ro-2-hydroxy-
362 Beazenesulfonic acid, (See ^-Toluenesulfonlc acid, « -(N-ethylanillno)
4-(M-echylani'liaonethaae)
363 Benzenesulfonic acid, 000091258
<>-fonnyl-
364 Benzenesulfonic acid, 000098715
jv-hydratino-
365 Benzenesulfonic acid,
4-hydroxy-3,5-dlaicro-
366 Benzenesulfonic acid, 000616853
4-hydroxy-3-nlcco-
367 Benzenesulfonic acid, 022117813
4-nechoxy-3-nitro-
368 Benzenesulfonic acid,
4-ne thoxy-3-(^-
Coluenesul t anamldo ) -
369 Benzenesulfonic acid, 000097063
4-mcthyl-3-nicro-
370 Benzenesulfonic acid. 000089361
£-(3-nethy l-S-oxo-2-
pyrazolln-1-yl)-
371 Benzenesulfonic acid, 000098475
nr-nicro-
372 Benzeneaulfonlc acid, 000080820
373 Benzcneeulfonic acid,
5-nltro-2-([>-
nltioanlllnu)-
374 Benzcnc.iultonlc acid,
5-nlcro-2-(£-coluiJlne)-
-------
Source* of
.Compound
Prucoaa In
Cli.-iptor 7*
TiiliU-. P;iRa
H-J?
Associated
Wastes
Waste
Tivncmc'iu
Total
Production
Kofi-fences
4. 41
4, 43
IS. 19
41
9b, 44
7e. 40
9b. 44
8b, 42
15, 47
4. 48
Reduction
Reduction
4. 48
17. 47
7e, 40
9b, 44
39, 78
2a, 32
8a, 41
8a, 41
32, 67
15, 41
38
8b, 42
38, 77
4. 32
25a, 59
5, 35
7b. 37
9b, 44
9b, 44
-------
h-33
TAHLK B-2. (Continued)
Item
No.
Compound
tCjmc and
y.>rr.:ulo
Chcm. Ahstr.
Renlitry No.
-
376 Benzenesulfonlc acid,
5,5'-urcyl*aebis[2-
anina-4-ncchoxy-
377 Benzencsulfonlc acid*
5,5'-ut*ylenebts[4-
Bethoxy-2-nitro-
378
379
380
381
332
383
384
385
386
387
388
389
390
391
Benzenesulfonlc acid,
5,5'-uKylenebls[2-oicro-
Benzeaesulfonyl chloride,
J-anino-5-aic co-
Benzenesulionyl chloride,
£-chloro-
Bcnzenesulfonyl chloride,
4-chloro-2-aethyl-
Benzcnesulfonyl chloride,
2-chloro-5-nltro-
Benzenesulfonyl chloride,
4-chloro-2-ntcro-
Benzenesulfonyl chloride,
4-chloro-3-olcro
Benzenesulfonyl chloride,
4-hydroiy-3-nitro-
Benzenesulfonyl chloride,
4-methoiy-3-nicro-
1,2,4-BenzeneCricarboxylic
»cld, }-amiao
1,2,4-Btnzenecrlcarboxyllc
acid, 5-hydroxy-
1 , 2 ,4-3enzenecricarboxylic
acid, 5-nitro '
Benzene , 1,2,4-crichloro-
5-nitro-
llH-Benzo{a]carbazole-
"*
020678335
000098602
(WSCR DC)
004533953
004533964
000097085
022117799
-
004961039
000039690
(WNX BC DC EC)
000086191
3-carboi-£-anisldlde,
2-hydroiy-
392 HH-Benzo(a]carbazole- 000084435
3-carboiylic acid,
2-hydroxy-
393 Benzole acid, 5- 005855787
aoIno-2-chloro-4-sul£o-
394 Benzole, 2-(3-aaino- 041378341
4-hydroxybeozoyl)-
395 Benzole acid, £-amino-
(7-(4-hydroxy-2-
nnphthalenesulfonic
acid)]
396 Benzole acid, 4- 053250343
(atnlnosul fonyl)-2-
chloro-
397 Benzole acid, £- 000085529
benzoyl-
398 Benzole acid, 2-
(4-carloxy-3-chloro-
bcnzoyl)-
399 Benzole odd, o_- 000135137
(carboxyatchyl)-
thio-
4250 orl-rat
103 orl-bdv
LDLo:32 mg/kg
Ipr-mus
-------
B-34
ProcesM In
Sources of Chapter 7*
^Compound Tab 11*, Past?
Prcccaa
Asaoclntrd
Wnsti'3
Waste
Tn'ntni'nt
Total
Product ion
Roforcncca
25a, 59
Reduce Ion
7c, 38
8, 38
25a, 59
9b. 44
7a, 36
28, 63
9a, 43
7a. 36
7b, 37
26, 62
8a, 41
41. 79
11. 79
41, 79
40, 79
23f. 55
23f, 55
39. 78
34a. 63
23h. 57
Kcduccloa
2)171
Reduction
2)172
Reduction
Reduction
39. 78
34a. 63
3Ab. 69 Oxidacion
43. 35
2)133
-------
Ken
So,
400
401
402
403
404
405
406
407
403
439
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
Compound
N.irae anil
Formula
Benzole acid, £-
(jv-chlorobenzoyl)-
Bcnzoic acid, 2-
chloro-5-chlo co-suit onyl-
Bonzolc acid, 4-
chloro-3,5-dinlcro- .
Benzole acid, 2-
chloro-5-nicro-
Eenzolc acid, o-
(4-chloro-3-
nltrobetrcoyl)-
Benzole acid, 2-
chloro-5-nicro-4-
sulfo-
Benzoic acid, o-
(3-chloro-£-toluoyl)-
Eenzolc acid, 2,5-
dichlorc
Benzolc acid, 2*
(2 , 3-dlchlorobecioyl) -
Benzole acid, 2,2'-
dithlodi-
Benzoic acid, 2-[3-
echyl-l-C4-aech>-l-3-
nltropheayljtriaienyl]-
5-sulfo-
Benzolc acid, 2-(4-
hydroxy-3-nicrobenzoyl)-
Benzoic acid, £-
cercapto-
Benzoic acid, 4-
izethoxy-3-nlcro-
Benzoic acid,
rf-nttro-
B-3S
TMiU: B-2. (Contlniud)
Choi. Abaci'.
ReKl*try Mo, Or.il Toy.isltv, Toxic llaznri! KatiitK
t«IJ!) LB50- r<-'1'!' Acute Clironlt: Toxlcolpc.v TLV Cnrclnosoi
OOOOS5563
000137644 _- _
000113978 _ ' '
002516963 ~ --
OOOOS5541 ' ~
. - _
015254270 '
000050793 LD33:1200 ng/kg _ - _
(QVR EC EG) . scu-nus
_.___ _
000119802
_ _
043046975 '
000147933 --
000059418 ' . .
000121926 . LD33:670 mg/kg
Ipr-rac
Benzolc acid, 2- - ~
(6-keto-2-oxobenzoxazoyl>-
Benzolc acid, o_-(g-
toluoyl)-
Beazophenone, 4,4'-
bls(diethylamino)-
Ecnzopheaone, 4,4'-
bisCdlmethylaniiao)-
Benzothiazole, 2-(£-
aninophenyl )-6-cathyl-
7*Ben20thlazole sulfonic
acid, 2-(4-anino?hynyl)-
6-nethyl-
Eenzo(b)thlophen-3(2H>-
one
IH-Benzotciazole.
1,2,3-
Eenzoxazole, 2-oeChyl-
Ecnzoxozole, 2-o«chyl-
5-nltto-
2(3ll)Bcnzoaxa7.olone
2(3ll)B«nzoxalone,
6-nitro-
000003552
000090937 ~
000090948 .
000092364
000130176 --
00013-0030
000095147 L)U L)U Led animal exp. indicate
(T56 3M.-.TU) S)U S)U mod. toxl'city, LB33:1300
mg/kf*, Ior-rou3
000095216 717 orl-rat ~
(T56 BS DOJ C)
032044518
000057494
004694911 ~ '
-------
Procoas In
Sources of Chapter 7* Associated Wnslu . Totul
Compound Table. PJKe Process Vnscoa TivaCricnr Product ion Uses Roforencua
34a. 68 -- -- -- --
_ 10, 46 '
_ 3. *6 - - -- - - -
10. 46
34a, 68
39, 78 Oxiiaclon
_ 12, 69 -- ~
_ 8. 48 - - WS4
34a. 68
43, 35 - -- .
7e. 40
34a, 68 -
43, 35 ..
21, 50
4, 35 Oxidation . 2)187
34a, 6S
34a, 68
6, 33 - .
6'7' M 0.051 (0.112)- .
1974
17, 66 " '
17. 66 '
43, 35 "
4f 39 _ _ . _ _ 2)199
3)444
26. 62 - -- ~ - . "
26. 62 ' ~
26. 62 -- ' '
26, 62 " ~
-------
TAIll.i: lt-3. (i\>ntim..'J)
1C cm
No.
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
.448
449
450
451
452
453
Crapound
N.itui! n rtd
F.Tnuln
Benzoyl chloride.
o-n 1 C ro-
Bcnzyla=lne, N-ecliyl- .
S-phcnyl-
4" ,4" '-BUcctanllide
4',4'"-51aceca»illde
3',3'"-dlainlno-
4' ,4" '-Biacecantllde,
31,3'"-dlnlcro-
ll.l'-Btancliraccne]-
9,9'.10,10'-cecrone,
2,2" *-3i-2-naphcho-o-
anlsldiie, 3',3'"-
dlhydroxy-
Biphenyl, 4,4'-dlanilno-
3,3'-dichloro-,
hydrochlorlde
ll.r-Blphenyll-4,4'-
diamlne, 2,2'-dinethoxy-
U,l'-Biphenyl]-4,4'-
diamlne, sulface
3,3'-Bl?henyldlol, 2,
2'-dinl:ro-
2,2'-Bl?henyldlsuUonic
acid, 4.4'-dianino-
3,3'-3l?henyldlsul£onic
acid, 4,4'-diaaino-
3-Blphezylsulfoalc
acid, 4,4'-diamtno-
3, 3*. 4, 4'-
Blphenylcecramlne
(2-m'-B£tolyl]-4,4-
diamlne
(n,m'-B:tolyl]6,6'-
dlsulfoaic acid, 4,
4'-dlanlno-
Butanaalde, N,N'-
(S.S'-dlaechylll,!1-
blphenyl)-4,4'-dlyl)
Carbazole, 3-aalno-9
echyl-
Carbazole, 9-echyl-
Carbazole, 9-echyl
3-nltro-
H,N'-Carbonyl-bls<4-
nechoxy- aethanilic acid)
Carboxcyrll, 4-hydroxy-
1-nechyl-
£-Crcaldlne (See Aniline
p-Crosol, 2-nlcro
2,3-Creaotlc acid
Cyclopenca-[cdJ-
Chrm. Ab»tr.
Ri'Klstry No. Ov;il Toxlslly. T.-xlc Hnznrd Kit rim;
IWLN) L050' "*' *s Acuti- Chronic
000121904 Ci&O orl-rnc
(WNS CVC)
000092391
004471107
(1VMS DR DMVl)
... _ «
006378901
019634903
.
~ -~
000091941
(ZR EC DR DZ CC)
004746752
021135709
__ « .
000117613 --
003365900 v
002051890 --
000091952 LDLo:3000 ag/kg
orl-rac
_
028425550
000091963'
144 orl-rac
(T B656 HNJ DZ H2)
. _
_
_
LDIx>:4650 iR/kg
orl-rac
, 2-oechoxy-5-mechyl-)
000119335 3360 orl-rat
_
Toxtcolov.v
<
__
_
^^
LDLo: 4740 r^/kg,
orl-rat
..
_
__
_
_
__
-_
.
TIV
,. _
»
1
^^
_
>M
DSOS: CAR 1
1
1
1
__
^_
__
^_
1
1
_
__
.^
._
~
TDLo:5300 ng/kg/35WC
TFX:CAS orl-rae
TDLo! 26 pn/kg/50W
TXX: CAR orl-rat
TDLo: 6.5 Bg/kg/M«
TFX: CAR scu-rac
TDLo:90CO ng/kg/30D).
TFX:NEO orl-rac
phenalene, lH-,5,7-
dlkcco
-------
11-3::
Proe.ess In
Sources ot Clianier 7*
CO..IP.H.I..I Tal.U-. IM.-.c fro,-.
AssneliiU'J
Ujir.fes
w.isiu Tumi
Tivairaenr ProJin-i i. >:i
Rufereiire..-!
4, 35
6,7, 33
25a, 59
25a, 59
25a. 59
25. 69
Reduction
(0.217) (0.482)-
1974
2)201
2)215
7c, 3S
7b. 37
2)173 '
7c. 38
25a. 59
26, 62
5. 35
25a, 59
15, 59
15, 59
25a. 59
29a, 64
38, 77
Alkaline
Reduction
Reduction
Reduction
Alkaline
Reduction
Reduction
2)221
29a, 64
20, 36
6, 36
6. 36
8b, 42
3, 35
2)296
15, 47
9, 46
1. 31
2)352
-------
Ue-
No.
454
455
456
457
453
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
473
479
480
481
482
Compound
N:imo and
Korir.it la
Dtanillnc, 4.4'-
isapropyllJene
Dianilinc, 2,4'-thlo-
Dlanlllne, 4,4'-Chto-
Di-o_-onisldtne, 4,4'-
cyclohcxylidene-
B-39
TAIHJ; B-2. (CoticliuifJ)
Chen. Abstr.
Rcelstry No. Ornl Toxlclty. Toxic Il/i:nr-
chlorophtnyl)-
Hydrazlne, l-(5-
chloro-o-colyl)-
Hydrazlne, 1,2-
diphenyl
2-Hydrazlne9ul fon Ic
acid. 1-U-
anchruqulnonyl)-
Kydroxylnmlnu,
N-p!ionyl-
000135356 224 orl-raC L)U L)U
(RNUSMR) . S)U S)U
021337939
(See Eehanol, 2-anlllno)
000122985 2230 orl-rat
(Q2MS)
_ _
000092002 _ '
000092502
01333S602 .
000093903 2830 orl-rae
(Q2NUR)
016365278
000102385
.
026193118
001073694 .
.
000122667 Ml orl.rae -
(RMMK)
0001.00652
(QMR)
"
'
1
TDLoiSOO rig/kg
TFX:SKN skn-hsn
TDLo:37 gni/kg/61W
TFX:CAR skn-mus
-_ _
r- - .
.
_ _
_
TDLo:16 gm/kg/m
TFX:HF.O acu-rat
U>Lo:5!) cn
scu-rbt
-------
11-40
Sources of
Compound
Procoaa In
Chapter 7* Associated Wn.ste Tocnl
Tnblt', PaRa Process W.istos Tr«-atn:ont Production
2c. 34
22. 34
2c. 33 -- .
7c, 38
list's References
_
_
_ _
19,4. 33
25c. 61
«
2Sc. 61
22. 37
2)1149
3)609
25c, 61
28. 63
2b, 33
2b. 33
25b. 60
6-10. 33
30. 66
2c, 34
25c. 61
28, 63
25c. 61
25c, 61
29b, 65
35, 75
4, 43
4. 64
25a, 59
35,75
25a. 59
Reduction
Reduction
Reduction
Reduction
Reduction
Neutral
Reduction
0.163 (0.360)-
1974
2)619
2)623
-------
Item
Xo.
483
484
485
486
487
4S8
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
»-'. 1
TABU 11-2. (CuiiclmieJ)
Compound Chcm, AbsCr,
S.vnc nnd Ruul.«Cry No. Or^t Toxlqlty, Toxtc Hnr.ird R»tlni»
F.-rm.ln (U'LS) . U>50' B1i>'llB Acitto chronic
Isophchalic ocld, 000099310
5-aaino-
IsophchaUc acid, 000618S82
5-ntcro-
4,4'-lBO?ropyllden«dianllino (See Dlanillnc, 4,4'-lsopropylidane-)
Mctaolllc acid (See Benzcnesul tonic acid, oi-nnlno
Hetanilic acid, 4-chloro (Sec Benzenesulfonic acid, 3-anlno-4-chloro-)
Ketanilic acid, 6-chloro 000038437
Mecanllic acid, 2-hydroxy- (See Benzenesulfonic acid, 3-aBino-4-hydroxy-)
Matanllic acid, 4-hydroxy- OOOC98373
Xetsailic acid, 4-hydroiy- 000096935
S-nitro-
Ketanilic acid, N,K-
dlethyl-
Hetaailtc acid, 6-
nicro-
Kethanesulfonlc acid,
aalllno-
Kechanesulfonlc acid,
o-anlslcino
Methanol, 4, 4 '-bis
(dleehylaolnophenyl)-
Naphchalene, 2-echoxy 000093185
(L66J C02)
Kaphthalena, l-ni:ro- 000086577
(L66J BMW)
2-Naphctalenecatboxamlde, 005442400 120 orl-rat
K-(3-chlorophenyl)-3-
hydroxy-
2-Naphchalenecarboxamida, 053232205
S-(ethoxyphenyl)-3-
bydroxy-
1,5-Naphthalenediol 000083567
1,3-Kapbthalene- 000118332
dlsulfo-lc acid, 6-
amino-
1.3-Napithalene- 000086657
dlsulfozic acid, 7-
amino
1,3-Napbthalene- 000118321
dlsulfocic acid, 7-
hydroxy-
1,5-Naphthalene- 000081049 -- L)U L)U
dlsulfonic acid S)U S)U
l,5-Naph:lialcne 000117624
dluulfozlc acid.
2-aoioo-
l.S-Napl-.chalene- 000131271
dlsulfor.lc acid.
3-amlno-
1,5-Naphchalene- 000117555
disulfoalc acid, 4-
aalno-
1,5-Nnphthalene- OOOU7566
dlsulfoalc acid, 4-
hydroxy-
l.S-Nnphthalene- 000117862
Toxicology
-_
'
LDLoilOO ng/kg
ipr-mus
.
TLV
__
_
_-
__
-
~
Cjirctnoi
H
_
_
--
dinulfo.tic acid, 3-
altro-
-------
B-42
Procena In
Sources of Chapter 7* Associated Waste Totul
Compound T.ihlc, I'.IKC Prov-csa Wnstcs Tri'atT.ent Production Vats
22, 30 Reduction .
22. 50 --
9b, 44 Reduction --
32, 67 Reduction .
8a, 41 Partial
Reduction
25a. 59
25a, 59
2c, 34 0.211 (0.466)-
1974
7c, 38 0.370 (0.816)-
1974
6,7, 33 . '
23g. 56 ' 2)775
23a, 50 -- 2)776
25b, 60 . .
9c, 45 _ _ _ _ _ _
23d, 53
23g. 56
23h, 57
15» 57 ~~ ~~ "~* ~ ^~ ~^
15, 55
15, 53 3)949
15, 57 '
23d, 53 .
23d, 53 . .
15, 54 '
23d, 53 ~ "
-------
It en
So.
Compound
Niimo nnd
Formula
Chca. Abatr.
RcgUtry No.
(WIN)
OiMl Toxt
Toxic Hntnnl li.il Ins
.Acuto Chronic
Toxicology
TLV
CnrclnoEC
511 1,5-Naphthalcne-
dlsulfonlc acid, 4-
oltro-
512 1,6-Naphchalene- 000525371
dlsulfonic acid
513 1,6-Naphthalcne- 000129919
disulfonic acid,
8-aotno-
514 1,6-Maphthalene- 000117431
dlsulfonic acid, 8-
bydcoxy-
515 1.6-Na?hchalene-
disoltonic acid,
8-nitro-
516 1,7-Naphthalene- 000130234
disulfonic acid, 4-
aaino-5-hydroxy-
517 1,7-Naphthalene- 006361495
disultonic acid, 4-
(oenzoylaaino)-5-
hydroxy-
518 2,6-Saphchalene- 000581759
disulfoaic acid
519 2,6-Naphchalene- 006362045
disulfoaic acid, 3-
aalno-
520 2,6-Naphthalene-
disulfonic acid,
3-nitro-
521 2,7-Naphthalene- 000092411
disulfonic acid
522 2,7-Naph:halene- 000134349
disulfonic acid, 4-
acetamido-5-hydroxy-
523 2,7-Naphthalene- 030090404
disulfonic acid, 3-
aino-5-hydroxy-
524 2,7-Naphthalene- 000090200
disulfonic acid, 4-
aalno-5-hydroxy-
525 2,7-Naphthalene-
disulfonic acid, 4,4*-
bls(diechylanino-
benzhydroljsalc
526 2,7-Naphchalene-
dlsulfoalc acid, bls-
[(4-diechylaminophenyl)
cethyljsalc
527. 2,7-Naphchalcne-
disulfoaic acid, 4-
chloro5-hydroxy-
528 2,7-Naphthalene- .
disulfonic acid. 4,5-
dlanino-
529 2,7-Naphthalene- 000148254
dtaulfonic acid, 4,5-
dihydroxy-
530 2,7-Haphthalene-
dlsutConic acid, 4,5-
dlnltro-
531: 2,7-Naphchalcne-
dlaulfonlc acid, 1-
hydroxy-
-------
II-*.1.
Source:* of
Compound
ProccHt* in
Chaster 7*
IiiliU-. Pane
Process
Associate. J
Wn.stes
Wnstc
Tvvntnu'nc
Total
ProJ'.ii'tton
References
23d, S3
15. 52
23c, 52
23c. 52
23c, 52
23d, 53
23d. 53
15, 51
23b. 51
23b, 51
15, 51
23c, 52
23g, 56
23c, 52
NaOH
Fusion
8, 33
51
8. 33
51
23c, 52
23c, 52
23c, 52
23t>. 51
2, 58
Reduction
-------
B-45
TABU; 11-2. (coiuinuud)
It eta
No.
532
533
534
535
536
537
538
539
540
541
542
543
COM pound
K.IUIC and
formula
2,7-Naphthalcne-
dlsulfontc acid, 3-
hydroxy-
2,7-Naphchalenc-
dlsulfoutc acid, 4-
oltro-
1-Naphchalcne-
sulfonlc acid
l-Naphthalene-
sultonlc acid, 2-
ainc
1-Naphthalene-
aulfonlc acid, 4-
aaino
1-NaphChalene-
sulfoalc acid, 5-
amino
1-Saphthalene-
sulfonlc acid, 6-
amlno
1-Haphthalcne-
sulfonlc acid, 8-
aoxloo-
1-Naphthalene-
sulfoolc acid, 4-
amloo-3-hydcoxy-
1-Naphchalene-
sulfonlc acid, 4-
aalno 5-hydroxy-
1-Naphthalene-
aulfooic acid, 4-
anlno-3-hydroxy-7-
nitro-
1-Maphchalene-
sulfonic acid, 8-
aaillno-
Chen. Abstr.
Registry No, Oval Toxle.tty, Tonic tlnzard Siiltnt:
(VUN) LU50- mh/k*- Aaiu- Cl.r.-:it.c ToxJcoloj-.v TLV C«rc
000143754 .
OOOOS5472
000031163
000034866 .
000034899
000081050 '. .
000032757
000116632
000083647
006259638
m
000082768
544 1-Naphchalene-
eulfonlc acid, 3-
anlllno-S-^-hydroxy-
aniliao)-
545 1-Haphthalene-
sulfonic acid, 4,5-
dlhydroxy-
546 1-Naphthalenesulfonlc 000567475
acid, 2-hydroxy-
547 1-Naphchalenesulfonic
acid, 3-hydroxy-
54S l-Haphchalenesulfonic 000034371
acid, 4-hydroxy-
549 1-Naphchalcncsulfonlc 000117599
acid, 5-hydroxy-
550 1-Kaphthalenesulfonic 000132570
acid, 7-hydroxy-
551 l-Haphthalencsulfonlc 000117226
acid, 8»hydroxy-
552 l-Naphthalenesulfonlc 052918293
acid, 8-[(occhylphenyl)
aminoj-
553 1-Naphthalcnesulfonlc 017521005
acid, 5-nltro-
554 1-Naplithalcncsulfonlc
acid, 8-nlcro-
-------
B-46
Sources of
ConpounJ
Process In
Ctinptor 7*
T.lhK-, I'ajic-
Process
Wax to
Trt'tunu-ru
Total
PrcJuc tton
Roiferonccft
15, 55
2. 51
15, 52
23g. 56
15, 50
23d, 53
23h, 57
23d, 53
23g, 56
23d, 53
J3g, 56
23d, 53
23d. 53
23d, 53
23g, 55
23g, 56
23a, 50
23d, 53
23f, 55
23e, 54
23c, 54
23d, 53
23d, 53
-------
B-47
TAilLE 11-2. (Coulhu.i-U)
Item
No,
555
556
557
558
559
560
561
562
Compound
Name and
Formula
2-t!aphChalcn
-------
B-4B
Process! In
Sources of Chiiocvr 7*
Compound T.iblo. fav.v Prcn-caa
AnnoclaCcJ
UllSU'i
Wosto
Trvotmonc
Total
Production
Vftt
Reference?
IS, SI
23f. 55
2)776
231, S3
23b, SI
23f. 55
23b, 55
15. 57
23b, 51
231. 58
Reducclan
231, 58
23g. 56 Reduction
23h, 57
23g, 56
23h, 57
23£. 55
23h, 57
23h, 57
231, 58
23f, 55
23£, 55
23g, 56
23g, 56
15,1, 55
231, 58
5, 35
24, 58
0.005 (O.Oi:)-
1974
2)777
23E. 55
23f. 55
23h, 51
-------
MULE 11-2. iCviillnued)
ItCW
No.
Compound
Name tmJ
Formula
Chcra. Abacr.
Registry No.
(KIN)
Or.-.l Toxtcltv. Toxic
« i. ;t. * .1 i I.
Acutt--
Chronic
Toxlcclosy
TIV
581 2-NaphchalenesuUontc 018425746
acid, 8-nlcco-
S82 2-N3phch:ilenesulfontc 000134474
acid, 7,7'-ureylcnebl3
(4-hydroxy-
583
584
S8S
536
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
2-Nophth.ilenesulfonyl
chloride
1,4 ,5 ,8-Saphchalenc-
tetracarboxylic acid
2-Xaphchalenechlol
1.3,5-Saphchalcne-
Crlsulfonic acid
1,3, 5-Naphchalene-
crlsulfontc acid, 8-
«Blno-
1,3,5-Saphthalcne-
Crlsulfonlc acid, 8-
nicro-
1,3, 6-Sa?hthalene-
trlsulfoalc acid
1,3, 6-Saphthalene-
trisulfoalc acid, 2-'
aolao*
1,3,6-Naphchalene-
tiisulfonic acid, 8-
amlao-
1,3, 6-Naphthalena-
Ctlsulfonlc acid, 4-
hydroxy-
1,3, 6-Saph thalene-
trlsulfonlc acid, 8-
hydcoxy-
1,3, 6-Saphthalene-
crlsulfonic acid, 8-
nltro-
Kaphchallc anhydride
Naphchallolde
Naphchallmtde, K-
methyl-
2*!!aphthaolde, 3-
hydroxy-H- (2-hydroxy-
ethyl)-
2-Kaphthamide, >
hydroxy-X-1-naphthyl-
2-Maphthaalda, 3-
hydroxy-.N-2-naphchyl-
2-Haphthanllidc, 4'-
chloro-3-hydroxy-
2-SaphthanllldB, 5'-
000093116
000123972
000091601
(L66J CS1I)
006654644
017894994
~
000086668
000117420
00331*6027
038267311
00051SOS8
. 000081834
002332083
000092808
000132683
000092728
chloro3-hydroxy-2",
4l-dlm«thoxy-
603 2-Naphthanllldc, 4'-
chloro-3-hydroxy-2",
S'-dlBethoxy-
604 2-NaphchanUide, 3-
hydroxy-
605 2-IJaphchantilde, 3-
hydroxy-2-octhoxy-6'-
ncthyl-
004273921
000092773
LDLo::00 mg/kg
-------
B-50
Sources of
Corcivur.d
-
'
'
_
....
Process In
Chapter 7 * Associated Vnstc Total
Table, P.H-n Prrcirsa WAsti's Tn':itnuint Production
23b, SI
231, 53
44. 51
40, 31
44, 51
15, 53
23d, 53
23d, 53
15, 52
15. 56
23c, 52 --
15, 58 '
23c. 52 --
23c, 52 .
1, 31 Oxidation
41, 31
1, 31
23f , 55
23a, 50
23h, 57
9a, 43
40, 79 .
Uses Rofcrrncca
_
_
_
2)778
_
.
_ _
.
'
_ -_
' . --
_
20, 49
23£. 55
14, 47
-------
B-51
TAIID! li--'. (CouLlm:ed)
Ittrm
No.
606
607
608
609
610
611
Compound
N.imc ant!
Fornuln
2-NaphthanUldo, 3-
hydroxy-3'-nlcro-
2-S:iphcho-o-ani3lJlJe,
5'-chloro-3-hyJrox>
2-Naphtho-£-an is id tde ,
3-hydroxy-
2-Naphtholc acid, 3-
amlno
2-Naphcholc actd, 3.5-
dlhydroxy-
2-Saphchoic acid, 3-
Clicra. Absir.
Rc^i^try No, Oral Toxl«;itv. Toxic HnriiMl iviitLnK ^^^
(>-'l-N) IU50' "«'''" Acute Clir.-nU TcxicoloKv TLV r«r',-l n.,»n^^k
000135659
000137520 -- _ '
000092795 '
005959524 ... _
OOOOS9350 .
000092706 800 orl-nus
hydroxy- (I.66J CVQ DQ)
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
"633
634
635
636
2-Naphchoic acid, 3-
hydroxy-5-sul£o-
2-Haphthol
1-Naphchol, 5-amino-
1-Naphthol, 8-aatno-
2-Kaphchol, 8-arainc
000056646
000135193 2420 orl-rac ~ '
(L66J CQ)
OOOOS3S56
002834915
'
l-Saphchol, 7-aaino-3-sulfo- (See 2-Naphthaleaesulfontc acid, 6-aat3O-4-hyiroxy-)
2-Naphthol, 5-aaiac
2-Kaphthol, l-nicro3o-
5-Haphchol, 1-amino- (See
7-Naphthol, 1-aolao- (See
8-Naphchol, 1-aaloo- (See
l-Naphchol-3-sulfonic acid
l-Naphchol-3-sulfonlc actd
2-Naphchol-6 sul fonic acid
2-Naphchol-8-sul£onic acid
Saphtho[2,l-6]chtophen-l
(2HJ-one
2-Naphtho-o-toluidida,
3*-chloro-3-hydroxy-
2-Naphtho-o-colutdide,
4'-chloro-3-hydroxy-
2-Napheho-£-coluidida,
3-hydroxy-
2-Naphtho-£-toluidida,
3-hydroxy-
Kaphch-(l,2-d)l,2,3-
oxadlazole-5-sulCoalc
acid
1-NaphChylaoine
1-Naphthylamlne ,
K-echyl-
2-Naphcliylanine
2-Phcnazlnol, 8-
«nino-7-octhyl-
000036975 . ''--
000131919
1-Naphchol, 5-amioo-)
2-Naphthol, 8-anlno-)
1-Naphchol, 8-aoino-)
, 6-aoino- (See 2-Naphchalenesulfoaic aclj, 7-a=ino-4-hydroxy->
, 6-aailino- (See 2-Naphthalenesulfonic actd, 7-anilino-i-hydroxy-)
(See 2-Naphchalenesulfonic acid, 6-hydroxy-)
(Sea 1-Naphchalenesulfonic actd, 7-hydroxy-)
000032600 .
_ .
000092762 ~ '
000135615
_ _ __ _
000233721 -- ~
025168109 779 orl-rat L)irr:2 L)U USDS: CAR *ea - Incriminated
(L66J BZ) S)ing:3 S)ing:3 as cause of urinary
inh:3 inh:3 bladder cancer
skn skr. TDLo: 25 og/kg/
abs:3 abs:3 TFX: NEO acu-cua
000118445 -- -- ~ .
000091598 727 orl-rac USOS: CAR TDLo:31 gm/kg/YI
(L66J CZ) . TFX: CAR orl-rat
LDLo: 200 ag/lg^
TFX i CAK ipr-^^B
TDLO: 13 oR/kg^^
TFX:CAK par-cu»
-------
H-52
Pror.'UM In
Sources of Chapter 7* Associated Wnste Totil
Compound T.il'lo, P.ijj" Procusa Wnst.!> Tri'otmcnt yroJu.-l l.'n Una Reference*
25c. 61
_ 18, 48 --
9a, 43
23f, 55
231, 55 -- .
23f, 55 2)779
15, 55 .
1. 51
23d, 53 '
23d, 51
23b, 51
1, 56
44. 51
29a, 64
2t>, 65 . " "
29a, 64
30, 66 . .
4, 56 -- '
23a. 50 - - -- 2)782
3)950
8,10. 50 ' .
238. 56 - - - - - 2)782
4, 47 Oxidation .
16, 63
-------
I ton
No.
637
633
639
640
641
642
643
644
645
646
647
648
.649
650
651
652
653
654
655
656
657
653
659
.660
661
662
663
664
*65
Compound
Name and
Formula
oj-Phenotldlne
m-Phene tiding, N,
tt-dlcthyl-
n-Phenetldlna, 4-nltroso-
N.N-dlethyl-
jj-Phenetldlna , 3-nlcro.-
Phenetole, £-nitro-
Phenol, pj-N-acetylaalno
11-51
TAHITI tl~2. (Continued)
Clicm. Abscr,
Registry No. OM! Toxlcllv. Toxic Ho:.ircl Kiillm;
O-'LN) LJW nI«'kS Acute Clirouiv Toxioolo^v TIV
000156434 L)U
S)lng:3
lnh:3
skn
abs:3
_ _ ._ - _
027292622 .
000100298
(See Acetanllide. 4'-hydroxy-)
C«rclm>«<4
Recogutr.ed
carcinogen
.
Phenol, 4-N-acetylamino 2-nicro- (See Acetanide, N-(4-hydroxy-2-nltro?henyl-)
Phenol, o_-anino-
Phenol, £-aaino-
Phenol, 2-amlno-4- .
chloro-
Phenol, 2-aoinc~4-
chloro 6-nitro-
Phenol, 2-aaIno-4-
( «. -c -dinethylbenzyl)-
Phenol, 2-amino-4,
6-dinitro-
Pbenol, 4-anino 3-
(2-nethylanilino)-
Phenol, 2-anino-4-
(methylsulfonyl)-
Pheaol, 2-anlno-5
nltro-
Pheaol, 4-aiaino-2-
nitro-
Phenol, 2-aolno-4-
(1.1,3,3-tetra-
oethylbucyl)-
Phenol. 4-(4'-amlno-
3'-toluidlno)-
Phenol, oj-anlllno-
Phenol, _£-anllino-
Phcool, 2-chloro-4,
6-dlnltro-
Phenol, 4-chlorg-2,
6-dlnltro-
Phenol, 2-chloro-4-
nttro-
Phenol, 4-chloro-2-
nltro-
Phenol, £-cyclohcxyl-
Phenol, 2,4-dlnmlno,
dihydrochloride
Phenol, 2,6-dlbcomo-
4-nltro-
Phcnol, m-dlcthylaalno-
000095556 LDU>:37 eg/kg
(ZR BQ) scu-cac
LDjo:20° a8/k8 Ipr-ous
000123308 375 orl-rac LDLo:470 og/kg
(ZR DQ) acu-Dus
000095852
006358083 '<
024133651
000096913
_ ~ .
000093306 .
000121880
000119346
006073207
0000101188
000122372 __ _ _ _
000946315 LDLo:500 ng/kg
(WNR EQ CG ES«) orl-rat
000038879
000619089 LDLo:100 =3/kg
(WNR DQ CC) orl-rat
000089645 _ _
001131603 --
000095863 '
000099285
j
000091689 _ _
»
~*
'
--
~~
~~
-------
n-5'.
Compound
In
7*
Pnvosa
Associated
TtvnEnK'nc
Total
Hroii.ict Ion
45. 45
Reduction
25«, 59
25a, 59
9c. 45
9c. 45
26, 62
Reduction
2)359
27.
18.
13.
26,
32.
29a
31,
26,
27,
26,
63
48
48
62
67
. 64
67
62
63
62
Reduction
Reduction
Reduction
Partial
Reduction
Reduction
Sapoalficacion
Reduction
2)359
31. 67
35, 76
20, 49
9c. 45
18, 48
9c, 45
18, 43
31, 67
7e, 40
12, 63
2Sa. 59
Reduction
2)861
2)861
-------
B-55
TAB UK U-2. (Continued)
K_
T66
667
668
669
670
671
672
673
674
>5
676
677
673
679
630
681
682
683
684
63S
686
067
688
Compound
Niimo and
FiTnmln
Phenol, 4-( « , -=. -
din«thylbci>:yl)-2-
nitro-
Phenol, 2,4-dlnltro-
Phenol, tt-nicro-
Phenol, c~nlcro-
Fhcnol, 2-nitro-
4-occyl-
Fhenol, 4-nlcroso-
»-Phenylencdiaeiine
o^Phenylenediaraine
jg-Phenylenediamine
B-Phenylenediatalne , 4-
chloro-
jj-Phenylenediaaiae, 4-
chloro-
CUc.n. Abstr.
Registry No. I
(KIJO
024133640
000051235
(WNR BQ EMU)
000554847
(WNR CQ)
000083755
(WNR CO.)
024777057
000104916
(QR DNO)
000108452
(ZR CZ)
000095345
(ZR. BZ)
000106503
(ZR DZ)
005131602
000055830
m-Phenylenediaalne, 2-chloro-5-sul£onic acid
n-Phenylenediamiae, 4
methoxy-N (l)-phenyl-
jr-Phenylenodlamine, 4-
methoxy-
o-Phenylenediamioe, 4-
nltro-
Phthalic anhydride, 3-
nltro-
Phchallc anhydride, 4r
nitro-
Picrlc acid
Froplonitrile, 3-
(N-acecanilino)-
Proplonlcril", 3-
anlnilo-
Proplonltrile, 3-
(N-butylanillno)-
Proplonltrllc. 3-
(M-ethylanlllno)
Proplonlcrllc, 3-
(p.-forayl-N-nothyl-
anllino)'
000615054
000615054
005131588
000503112
000610275
000083891
(.vys. BQ CNW E.W)
001075769
000143373
000094213
Dr;il ToKlcltv. Tcxfc !;n:ard Rjitlni;
L1'50, ««/k8 Acnri.
«
30 orl-rat
447 orl-rac
2823 orl-rat
LDLo:80 mg/kg L)irr:3
orl-rac alr:l
S)ing:3
lnh:3
skn
aba: 3
L)irr:3
alr:l
S)ing:3
inh:3
skn
abs:3
LDLo:100 ng?kg L)irr:3
orl-rat alr:l
S)ing:3
inh:3
ska
abs:3
-
(See Benzenesulfonic acid.
__
_
'
LDLo:120 mg/kg L)irr:2
orl-rbt alr:l
S)ing:3
inh:3
skn
abs:2
-_
ClironU- Tcxlcolocv TLV Care
T
_ _
LDLo:83'zg/kg
ivn-dog
LDLo:100 =g/kg
Iffl-dog
_
LOLo:250 =g/kg
ipr-ous
L)alr:2 Systenlc poisoning
S)ing:2 is uncommon
inh:2
»kn
abs:2
L)alr:2 LDLo:600 =g/kg
S)lng:2 scu-rac
iuh:2
skn
abs:2
L)alr:2 £-lsomer is xost US OS 3lr:WA
S)ing:2 toxic although 103 uz/c (skn)
inh:2 systemic poisoning
skn is uncooron
abs:2
4-chloro-3,5-diamino-)
_ __
L)irr:2 can cause .llergic "SOS airrWA
alr:2 Or Irritative 0-1 «/<
S)ing:2 deroatlcis
lah:2
skn
abs:2
_
_
-_
_
-------
I'nwi-s* In
Sources of Chapter 7* Asuocinteil Wastu Totul
I Conpoi-.mt T.ilili-. P;IK« Pv.voss Uti.-ti-.* Tri'nl :r.»-iir Fn-.l-.i^t Inn
-- 26. 62 - --
7e. 40 KmissIiMi f.iccora: 0,45
hydrocarbon - J.O, (1.0)-
SO - 1.0 1975
25c. 61 --
7b. 37 .
_ 26. 62
31, 67 '
25c, 61 Reduction
Usi-fl R
2)863
2)866
2)866
2)866
2)879
3)1013
40, 39
2)879
3)1013
9c, 45
Reduction
2)880
3)1013
7e, 40
18, 48
Reduction
Reduction
18. 48
7c, 38
25c. 61
34a, 68
34a, 63
32, 67
Reduction
Reduction
3)1029
2)929
2a, 32
2a, 32
2b. 33
2b, 33
6, 34
-------
D-57
TAHI.K U-:. (.Continued)
Cliom. Abbtr.
Registry Ho.
(WIN)
Ornl Toxic try, Toxic Hor.iril Rulm;
I-U^p, mu/tj; Actite Cluv.iU-
689
690
691
TrxUolocv
TLV
CnrctnoRf.
Proplonlcrile. 3-1 (S-
*-fornyl-3-nechylph<;iiyl-
(i-n*thyl)aaluo)-
Proplonitrlle, 3-(ti-
ecthylanilino)-
Proplonlcrlle, 3-[(N-
methyl-N-3-cethylphenyl)
aaino)-
000094343
692
693
.694
695
696
697
693
699
700
701
702
ft"
W
704
705
706
707
708
709
710
711
712
713
714
715
716
717
v
2-Pyrazolin-5-one,l-(£-
chlorophcnyl)-3-nothyl-
Z-Pyrasolin-S-one, 1-
oethyl- ~
5-Py razolone , l-(4-chlocophenyl)-3-methyl- (See
_
__ m- . __
2-Pyrazdin-5-one, l-(£-chlorophenyl)-3-methyl-)
^ ^
5-Pyrazolone, l-(2-chloro-5-sulfophenyl)-3-nethyl- (See Benzenesulfonlc acid, p_-chloro-3-(3-meth?l-5-oxo-2-pyrazolin-l-yl-)
Pyrazoloae, l-(4-chloro-2-sulfopheayl)-3-sethyl-
i-Pyrazolone , 1- (2 , 5-dichlo ro-4-sulf ophenyl ) - 3-m
S-Pyrazolone, 3-methyl-l-(4-sulfophenyl)- (See
(See Benzenesulfonic acid, cj-chloro-6(3-nethyl-3-oxo-2-pyrazo]oa-l-yl-)
ethyl- (See Beazenesulfonic acid, 2,5-dichloro-4-(3-nethyl-5-oro-2-pyrazolin-l-yl-)
Benzene sulfonic acid, p^(3-methyl-5-oxo-2-pyrazolin-l-yl-)
Purpurln (See Anthracenedione, l,2,4-trihydroxy-9,10-)
4-Quinoneinine , H-
(4-aailinopheayl)-
Resorcinol, 4-chloro- 000095885
Salicylic acid, 5- 000089576
anico (ZR tXJ CVQ)
Salicylic acid, 5- 000096979
nitro-
Sulfanilic acid 000121573
Sulfanlllc acid, N, 004986703
N'-dibenzyl
Sulfanilic acid, 2, 000088506
5-dlchloro-
Sulfaoilic acid, 2- 000712243
nltro-
Sulfanilyl chloride, 000121608
K-aeetyl (HSGR DMV1)
Sulfone, 4-chloro- 000097074
3-nitrophenyl oethyl-
Sulfone. 2-chloro- 021081743
5-nitrophenyl oethyl-
Sulfone, £-chlorophenyl 000098577
nethyl-
o-Tolualdehyde, 4-[(2- 000092104
chloroethyDechylamino]-
Toluene, n-chloro- 000108413
Toluene, p_-chloro- 000095498
Toluene, £-chloro- 000106434
_ ^~
. ~ ~
U)Lo:313 og/kg
Ipr-mus
_ _
-
L)U L)D Animal eiperinents
S)U S)U suggest lou toxicicy
and slight irricatioa
*~ -« '
,
'_ '
TDLo:5100 ug/m3
ihl-hum
-_
._ __
_
_
_ _
«
__
_
, _,
_
Toluene, 2-chloro- 000121868 3020 orl-rat
4-nlcro-
Toluene, 2-chloro- 000083421
6-nltro-
Toluenc, 4-chloro- 000089593
2-nttro-
_ _
_
-------
Sources ot
ComitounJ
Proci'SH In
Chapter 7*
TabU-. I'iii-.i-
It-SB
Anuociatcd
Process
Vnstu
Trvntmi-nc
Total
Prm'uctlon
Vset
28. 63
2c, 34
28, 63
4. 43
4, 64
19, 49
12, 76
36, 76
36, 76
13, 32
Reduction
Baking
2)1043
2a, 32
15, 48
2Sc. 61
2a, 32
7b, 37
9a, 43
7a, 36
30, 66
28, 63
39. 78
12, 76
12. 66
12. 64
3, 64
12, 76
2.553 (5.623)-
1974
2)1091
2)1139
-------
fcm
KL
^
719
720
721
722
723
724
72J
726
727
B-59
TAIIIJC B-2. (Continued)
Compound Clicm. AbtHv*
H:ioe and Ri-Klstry Ho. Oml ToxUltv. T.'xlc Hn:nnl Rnttm:
Fonmiln (ULS) '"SO- mii'kK Acute Cl,ro:il.- Toxicology
Toluene, 4-chloro-3- 000089601 ~
nltro-
2,4-Toluonedisulfonlc 000121040 '
acid
Toluene, 3-ner.hoxy- (See Anisole. m-methyl-)
Toluene, nj-tnethoxy-
2-ntcro-
Toluene, 4-_ethoxy- -
3-nltro-
Toluene, o.- . 000088664
trlchloro-
a-Toluentsulfooaalde, _____ _
5-amlno-
a-Toluenesulfoaamide, 006269916
i-nltro-
£-Toluenesul£oaa_dde; ______ __
TLV Cntcino,
_
__ ' __
__ __
^ _ __
__ __
__ »_
_ _
723
N-[4-(5-hydtoxy-2,7-
naphchadeaedisulfonlc
acid)l-
f-Tolueaesulfonace, 8-
»alno-3,6-disulfo-l-
naphthyl
729
730
r
732
733
734
735
736
737
738
739
740
.741
742
743
1
w *
o-Toluenesulfonic acid,
£>-Tolueaesul£onic acid,
6-anino_
£-Toluenesulfonic acid,
2-ani_o-5-chloro-
tfr-Toluenesulfonlc acid,
6-aaino-4-chloro-
£-Toluenesulfonlc acid,
3-chloro-
£- Toluenesulfonlc acid,
3,5-diaaiino-
^*Toluenesulfoaic acid,
3,5-dinitro-
n-Tolueaesulfonic acid,
- (K-ethylaaillno)-
oj-Toluenesulfonic acid,
5-nitro-
toluidida,
toluidlde, 2'-nltro-
chloride, 3-chloro-
o-Tolucnesulfonyl
chloride, 5-nicro-
p_-Toluenethtol, 4-
chloro-
D-Toluldlne
o_Toluldlne
000113837
000098339
000088539
000088517
000088904
000101111
000121039
000599860
000121028
017178017
000108441
(ZR C)
000099945
(ZR B)
974 orl-rat
L)irr:2
alr:l
inq:2
S)ing:3
lnh:3
akn
L)alr:l
S)lng:2
inh:2
skn
abs:2
Material can produce t'305 alr:WA
severe systemic 5 poa
disturbances, althouRh t'503 alr:T.VA
good data for comparing 21 as/m3
Che o, m, and p_ Isoaers
aru not available
L)lrr:2 L)nlr:l
alr:l S)lnR:2
lnq:2 lnh:2
S)lng:3 skn
lnl.:3 nbs:2
Material ccn produce
severe gyst&tntc
disturbances, although
good daCo lor comparing
the o, in, and 2.
arc not avaliable
VSOS alr:TW\
S spa
CSOS alr:TVA
22 an/ml
A recognized
carcinogen
A recognll
carcinogen
-------
Sources of
^ Compound
Process In
Chapter 7*
Talilc. Pano
Process
ll-i.O
Associated
.Vnstcs
Vance
Trr.Uinrnt
Total
Production
3. 76
15, 77
14. 47
15, 47
12, 78
30, 66
30, 66
23c, 52
Nitration
Reduction
23c. 52
30. 66
15. 66
39, 78
15, 66
12, 77.78
38. 77
38, 77
15, 33
5.15, 66
30, 66
30, 66
12, 78 '
30. 66
28, 63
28. 63
Reduction
Baking
Reduction
Baking
Reduction
_ .
Seduction
Reduction
3.431 (7.546)-
1974
19. 64
Reduction
3)22?
-------
B-fi!
T.\III£ tl-2. (Cuutliim-il)
Compound Chcra, Abdir.
hem (fane and Registry No. Oral Toxlcltv, Toxic Jtnrnri! K.itlni-. .^
M- Formula (WIN) k^SO' "'K'^-S Acute
w
745 £-Toluldlne 000106490 L)lrr:2
(ZR D) nlr:l
lng:2
S)inS:3
lnh:2
skn
abs-.l
CIllVLlK:
L):.lr:l
S)i..S:2
lull : 2
sku
ubs: 2
Toxlcotorv
Material can product-
severe syntu^lc
disturbances, although
good data for comparing
the £, a, and ^ Ittooiiirs
are not available
TLV
USDS air:WA
5 ppo
USOS .ilr:T.
-------
B-6:
Prix-k-ss In
Sources of Chapter 7* Asooclui,/d Waste Tc:nl
ComiJ.nmJ Table. l'.i|-.o Prpi->-sa Wnate." Tri-mm-nt Prod-jetton Uaca Rot\"
30, 66 Reduction 2)1142
3)22, 1175-6
4, 63 - -
45, 64 --
30, 66 . 2)1143
29b, 65 Saponification
29a, 64 Reduction 2)1143
30, 66
29b, 65 ~~ ~ ~" ~~ " " ~""
29b. 65
28. 63
28. 63 --
29b, 65 .
30, 66
30. 66 - 2)1144
29b. 65
29a, 64
29a, 64
42, 79 Reduction 2)1202
-------
Compuund
NOIM anil
Fomulrt'
Chcro. Abstr.
Registry No.
(WIN)
Oral Toxlclty,
B-6J
Toxic Hngnnl K.itlny.
Acute Clivi'.'.K'
TABI£ B-3. OKCANIC DYES AKD PICJENTS-TOXlCI'Tf
Toxicology
TLV
C110005 Mordant Green
2 CI1Q006 Plgaent Green 8 015635537
CI10020 Acid Green 1
019331501
" D&C Green 8
CI10316 Ext. D&C
Yellow 7
006358696
000846708
6 " Acid Yellow 1 000846708
7 CI10333 Disperse 005124254
Yellow 42
8 CI10345 Disperse
Yellow 1
. 000119153
CI10395 Acid Brown 1
10 CIUOOO .Solvent Yellow 1 033063093
(ZR D5iUl«)
11 " Pigoent :
Yellow 98
12 CI11005 Disperse 000730405
Orange 3
13 CI11014 Basic Red 30
TDLo:1600 eg/Wg/2.;VI
TFX:CAR, sitn-rac
14 CIU020 Solvent
Yellow 2
15 CI11021 Solvent
Yellow 56
000060117
(1N1SR
DNUHR)
002481949
16 CI11043 Basic Violet 18
17 CI11052 Basic Blue 54 015000596
13 CIU085 Basic Red 13 014097031
800 orl-rat
300 orl-nus
TDLo:800 mg/kg/
40D. TFX:CAS.
orl-rat
TOLo:11 gn/kg/
12WC. TFX:N£0
orl-ous
-------
PROCKSS, WASTE, PRODUCTION AtS DATA
B-t>4
Sources of
Process
Nc*.
Process
Aafioclntcil
VMS ton
Vaato
Trcatci-nt
Total
Production
t!.res
IS
Nlcrosation
Filtration
Nlcrosacion
Filtration
Kltrosatlon
Filtration
Precipitation
Air: nitrogen oxide
Water: Inoryjnlc
salt solutions
Nitrogen oxide
furaes encnpe fron
a tall stack or pipe.
Usually no effort
has been made to
control fluid
effluents
Air; nitrogen oxide Nitrogen oxide 67.3 (US)-
Vacer: inorganic funws escape from 1973
salt solutions a tall stack or pipe.
Usually no effort
has been made to
control fluid
effluencs
Air; nitrogen oxide Nitrogen oxide
Vacer: inorganic
salt solutions anj
brines which cay
contain residual
amounts o£ metal
iotxs
fuces escape from
a tall stack or pipe
Usually no effort
has been made to
control fluid
effluents
Nicrosatlon Air: nitrogen oxide Nitrogen oxides 404 (839)-
Nitracion Water: inorganic are difficult to 1973
Filtration salt solutions and control by water
nitrogen oxides scrubbing
Replacement
Reaction
Filtration
Replacement
Reaction
Filtration
Dlazocizatlon
Coupling
Diazotization
Coupling
Diazoclzacion
Coupling
Diazotizacion
Coupling
Dlazoclzacion
Coupling
Water: brine
contaminated with
small acounts of
organic substances
Water: brine
contaminated with
small amounts of
organic substances
Water: brine
contaminated with
small anounCs of
organic substances
Water:inorganic
salts
Water: inorganic
salts
Vacer: inorganic
salts
Water: Inorganic
sales
Water: inorganic
sales
53.6 Q18)-
1973
2)29, Splmt
2)330. 103
Dlazbtizaclon
Coupling
Diazocizaclon
Coupling
Diazocizaclon
Coupling
Diazotlzacion
Coupling
Water: inorganic
salts
Water: inorganic
sales
Water: inorganic
sal trs
Waccr: Inorganic
salts
39.6 (87)-
1973
254 (559)-
1973
-------
to11
1
w
w.
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
'
Compound
N.tuio and
Forr-uln
CtlllOO Disperse
Orange 5
CI1U10 Disperse Red 1
C111115 Disperse Red 13
C111150 Disperse Red 7
CI11152 Disperse Brown 1
CI111S4 Basic Blue 41
CI11160 Solvent
Yellow 3
C 11 12 10 Disperse Red 17
CI11215 Disperse Red 5
C111250 Disperse Red 31
CI11255 Disperse Black 2
CI11270 Basic Orange 2
CI11290 Mordant
Brova 12
C111320 Basic Orange 1
C111365 Disperse
Black 1
C111450 Basic Yellow 25
CI11460 Basic Red 29
C111480 Basic
Yellow 24
CI11660 Plgtaent
Yellow 5
CI11665 Pigment
Yellow 4
CI11670 Pigment
Yellow 6
CI11680 Pigment
Yellow 1
CI11710 Pigment
Yellow 3
C111720 Pigment
Yellow 9
CI11725 Pigment
Orange 1
CI11738 Pigment
Yellow 73
CI 11740 Pigment
Yellow 65
CI11741 figment
Yellow 74
B-65
TAUI£ B-3. (Continued)
Clu'ci. Abacr.
KfKistry No. Ornl Toxiclcv. Toxic K.i:nrd R.itlnn
C.UO Lll50- "«'kK Acut.- Chronic Toxicology
00623:560 ' .
00:872528
0031S0812 ~
004540005
~
000097563
003179393 '
003769571
002475435
006232571
000532321 LDLo:158 mg/lcg
(ZR CZ DNUNR orl-ous
sea)
' ' .
005042546
006054484
041025676
_ ' _ _
_- .
001657165
004106767 ~
002512290
006486233
_ _. _
006371956 .
_ -_ _
_ __ _
r_ _ - __ '
TLV Carclnoccl
1 1
_ _ .
.
'. ~
.. >
_ _
_
TDto:158 gi
56WC. TFX:
orl-oua
'
_
_
_ _
_ __
~
__
_
_ -_
_
-------
Il-tG
Sources of
' -
.
-
Process
Co.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Proc,«
Dlazotlzatlon
Coupling
Dlnzotlzacion
Coupling
Diazocizacion
Coupling
Dlnzoclzatlon
Coupling
Diazocizaclon
Coupling
Diazocizaclon
Coupling
Diazocizacion
Coupling
Diazocizaclon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizaclon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazotizaelon
Coupling
Diazocizacion
Coupling
Dlazacizaelon
Coupling
Diazocizacion
Coupling
Diazociznclon
Coupling
Dlnzoclzaeion
Coupling
Diazotlz.t tlon
Coupling
Diozoclzaclnn
Coupling
AscOirinccd Vnfite
Wastes Tr>Mtr.t-nc
Ua^cr : Inorgnn Ic
salts
V-Uer: inorganic
salts
Vacer: inorganic
sales
Va_ce£: inorganic
sales
Vater: Inorganic
salcs
VaCor: inorganic
sales
Vacer: inorganic
sales
Vacer: Inorganic
sales
Vacer: inorganic
sales
Vacer: Inorganic
sales
Vacer: inorganic
sales
Vacer: inorganic
sales
Vater: inorganic
sales
Vacer: Inorganic
sales
' Vacer: Inorganic
sales
Vacer: inorganic
sales
Vacer: inorganic
sales
Vater: Inorganic
salts
Water: inorganic
sales
Vater: inorganic
salts
Vacer: inorganic
sales
VaCer: inorganic
sales
Vacer: Inorganic
sales
Vater: Inorganic
salts
Vncer: inorganic
salts
Water: Inorganic
sales
Vacer: inorganic "
salts
V_au:£: inorganic
sal cs
ToCi\l
Vroductton
160 (351)-
1973
~
123 (270)-
1973
46.4 (102)-
1973
221 (.487)-
1973
'
142 (31-3)-
1973
306 (674)-
1973
189 (415)-
1973
290 (637)-
1973
--
Use, Rcf,ronco.^.
_
.
2)331. 330
-------
km
I"
47
48
49
SO
51
22
53
34
35
56
57
53
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
Compound
Na=ie nnd
Formula
C111765 Figment
v Yellow 49
CI11767 Plg'Mnt
Yellow 97
C111770 Pignent
lollow 75
CU1055 Disperse
Yellow 3
CI11920 Solvent
Orange 1
CI120S5 Solvent
Yellow 14
CI12060 Pignent
Orange 2
CI12070 Light Pigment
Red 1
CI12071 Pigment Brown 2
C112075 Pigment Orange 5
" D&C Organge 17
CU2035 D&C Red 36
" Pigment Red 4
CU2090 Plgaenc Red 6
CI12100 Solvent
Orange 2
CI12120 Plgaent Red 3
CI12140 Solvent
Orange 7
CI12150 Solvent Red 1
CI12170 Pigment Red 40
CI12200 Mordant
Black 19
CI12210 Basic Blue 16 .
CI1224S Direct Red 76
CI12310 Plgaent Red 2
CI12315 Pigment Red 22
C112350 Pigment Red IS
CI12355 Pign>ent Red 23
CU2 360 Plgaent Red 31
B-67
TAIH.K B-3. (Continued)
Chca. Abalr,
RcKistry No. Ornl Toxlctly. Toxic llnznrJ Rut in?.
lULNl Ll>50' "V''^* Acme Chronic ToxUoloitv
._
012:25182 . .
_ _
002332408 .
002051S56
000542079
(L66J BNUSR6
CQ)
005410099
006410102 ~
_ .
003468631
003468S31
002314779
.002314779 '
006410135 --
002646175 LDLo:5000 mg/kg
(L65J BNUNR orl-rat
BS CQ)
002425856 '
003113976
(L65J BSUNR
B D4 CQ)
001229556
002553547 _
_ _
004569384 ~
001325639
006041947
006448959
003564225 --
006471494
.
TLV C*rr * '»«P ^^^*
.
TDLo:56 gn/kg/
52WC, TFXsNEO
orl-aus
~
.-
. _ _
_ _
TDLo:6 gm/kg/
52W. TFXiCAR
scu-mua
TDLo:80 mg/kg
TFX:SEO Imp-nua
_-
.
._
_ . _
-------
b-fiS
Sources of
Compound
~
--
'
-
~
Proccsi
No.
*
4
4 '
' 4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
DluzotUatlon
Coupling
Dlazoticatloo
Coupling
Dlazotigatlon
Coupling
Diazotizacion
Coupling
Diazotization
Coupling
Diazotizatlon,
Coupliag
Diazotizatlon
Coupliag
Diazotizatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupliag
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupliag
Diazotlzatloa
Coupliag
Diazotizatlon
Coupliag
Diazotization
Coupliag
Diazotization
Coupliag
Diazotization
Coupliag
Diazotizatlon
Coupliag
Diazotization
Coupling
Diazotizatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlnzoelz.ition
Coupling
Associated
Wnslo»
Water; inorganic
salts
Water: inorganic
salts
Hater: inorganic
salts
Water: inorganic
salts ,
Water: inorganic
salts
Water: inorganic
sales
Water: Inorganic
salts
Water: inorganic
sales
Water: Inorganic
salts
Water: Inorganic
salts
Water: Inorganic
salts
Water: inorganic
salts
Water: Inorganic
salts
Water; Inorganic
salts
Water: inorganic
salts
Water: Inorganic
sales
Water: inorganic
salts
Water: inorganic
salts
Water: inorganic
salts
Water: inorganic
salts
Water: inorganic
salts
Water: Inorganic
salts
Water: inorganic
salts
Water: Inorganic
salts
Water: inorganic
salts
W-itcr: Inorganic
salts
VjH£r: Inorganic
salts
Waste To t a 1
Tr»-ntr.n'nt Production Utius Refer
_
1704 (3,748)-
1973
256 (564)- 2)730
1973
_ _
--
364 (800)-
1973
_ _
5.0 (11)- -
1973
135 (296)- -
1973
.
2)330
814 (1,790)- '
1973
35.5 (78)- 2)330
1973
_ _
_
__
^
.
35.5 (78)-
1973
58.6 (129)-
1973
122 (2C.9)-
1973
-------
fe
^r
74
75
76
77
78
79
80
81
82
83
84
85 .
86
\
88
89
90
91
92
9?
94
95
96
97
98
99
100
101
102
Compound
Naiac and
Fornnita
CIU370 SoJturn PiRaent
Red 112
" Pigment ReJ 112
CI12330 Plgoent ReJ 14
CU2390 Pigment Red 17
CI12395 Pignient Red 13
CI12420 Pigment Red 7
CI12440 Plgaent Red 10
CU2460 Pigment Red 9
CI12465 Pigment Red 15
C112480 Plgoent Brown 1
C112485 Pignent Red 146
CI12490 Pigment Red 5
CI12515 Pigxent Red 176
C112690 Disperse
Yellow 8
CI12710 Plgaent
Yellow 10
CI12715 Solvent Red 8
CU2775 Pigment Green 10
CI12790 Disperse
Yellow 5
CI13010 Acid Dye 0
C113025 Acid Orange 52
C113053 D&C Red 39
CI13065 External D&C
Yellow 1
" Acid Yellow 36
C113080 Acid Orange 5
CI13090 Acid Orange 1
CI13095 Acid Yellow 63
CI13150 Acid Orange 50
CU3225 Mordant Brown 13
CI13250 tordant Btown 33
R-t>9
TAIIU: B-3. (Continued)
Chem. At>str.
Registry No. Orul ToxicHy, Toxic Jl.iznrd Katlm;
IWLN) LDr)0' "S'1* Acutu Cl.rimU ToxUolonv
00o33i4u2*
006535462
_ _ '
006655341
--
006471518
006410351
006410384
_
006410408 _
_ _ _ ' ._
006410419
_ __
006358492
006407756
_ _ '
006421654
006439538
000547530
063715571
000587984
000587984
000554734
_ _ _ _
_ _ _ .
006054804
003618620
TLV Carclnns
..
_ .i.
_
->
_
_
__ _ ^
_
'
__ __
_
~
~
! --
-------
Sources of
i Comfvutttl
r^
-
-
Process
NV.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Prcvosu
Diazotl:ation
Coupling
Diazotlration
Coupling
Diazocl:ation
Coupling
Dlazotliation
Coupling
Dlazotlratlon
Coupling
Dlazotl:aclon
Coupling
Diazotl:atioa
Coupling
Diazotizatlon
Coupling
Diazoclzation
Coupling
Dlazotization
Coupling
Diazotization
Coupling
DiazotUatlon
Coupling
Diazoclzatlon
Coupling
Diazotization
Coupling
Diazoelzacion
Coupling
Diazocization
Coupling
IHazocizaClon
Coupling
. Dlazotizacion
Coupling
Diazocizacioa
Coupling
Dlazocizacion
Coupling
Diazotizatlon
Coupling
Dlazocization
Coupling
Dlazoclzatioo
Coupling
Diazoclzaclon
Coupling
Dlazocization
Coupling
Diazoeization
Coupling
Dlazoclzat Ion
Coupling
Dtar.oclzncton
Coupling
Dlazot Izaclon
Coupl L.ig
An
Water;
salts
Water:
salta
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Uaterr
salts
Water:
salts
W.ifr:
S'lltH
Water!
nalts
300 l.i ted WnHCe Total
Vilnius Tr.'.-uncnt Production Udei Ref*i
inorganic
inorganic
Inarjanic 36.8 (31)-
1973
inorganic --
injrgaaic
inorganic -
inorganic ^
inorganic
Inorganic
inorganic
inorganic -'
Inorganic ~ 43.5 (100)-
1973
inorganic .
inorganic --
inorganic
inorganic
inorganic '
Inorganic .
inorganic '
inorganic
inorganic
Inorganic
Inorganic - 89.6 (197)-
1973
Inorganic '
iDorganlc
Inorganic
inorganic ~
inor^anic
inorganic
-------
km
E_
w
103
104
105
106
107
108
109
110
111
112
113
114
}is
116
117
118
119
120
121
122
123
124
125
126
Compound
Ndmo and
>Vrrailn
C113265 Mordant Brown 49
CI13360 Mordant Dye 0
CI13361 Acid Green 35
CI13390 Acid Blue 92
CI13425 Acid Green 12
CI13900 Acid Yellow 99
" Solvent
Yellow 19
CI13906 Acid Yellow 151
CI13920 Direct
Yellow 8
CI13950 Direct
Yellow 27
CI14025 Mordant
Yellow 1
CI14030 Mordant
Orange 1
CI14055 Mordant
Yellow 14
C114110 Mordant
Yellow 20
C114130 Mordant
Yellow 5
C114135 Mordant
Yellow 36
CI14155 Direct Green 28
CI14170 Acid Yellow 65
CI14250 Mordant
Brown 19
C114270 Acid Orange 6
CI14625 Acid Brown 6
CI14640 Mordant
Black 3
C114645 Mordant
Black 11
C114700 FDiC E-d 4
B-71
TABU: 0-3. (Contima-j)
Clicc. Abatr.
RoKiitry No. Oml Toxtclcy. Toxic ll,i:nnl R.-ulnu.
t-'UO U150- in*'l-S Acnci- Chronic Toxicology TLV Carcinoc-el
-. -_
_ _ _
-.
003S61732 LD30:450 og/kg
(L66J BQ OS- tvn-mus
WQ HSU!) JSUN
B_66J EMS&
CSUQ &-SA- 3)
__ __ _
010343535 _____
010343535* __ _ _ _
_____
__ _ _ _
'
000584429
001718349 ' .
__
006054984 -
'
006471095 ' .
__ _ _ _
_ __ _ _ '
000547579
006409105
003554145 ~
001787617
004348532 TDLo: 42!
(L6W BQ 65WC, T?
CNWR B D orl-rat
ESWOS ESWO
--NA- 2)
127
CI147H Acid Red 4
005*58399
-------
B-72
Source* of
kCompounJ
r
_
_
_
_
_
_
Process
No.
4
4
4
' 4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Diazotizatlon
Coupling
Dluzoctzatlon
Coupling
Diazoclzatlon
Coupling
Dlazocizaclon
Coupling
Diazotizacion
Coupling
Diazocizatlon
Coupling
Diazocizaeion
Coupling
Diazocizatioa
Coupling
Dlazoclzacloa
Coupling
Diazocizatioa
Coupling
Dlazocizaclon
Coupling
Diazoclzacioa
Coupling
Dlazocizaclon
Coupling
Diazotizacloa
Coupling
Coupling
Dlazocization
Coupling
Dlazocizaclon
Coupling
Dlazotizaticn
Coupling
DlazocizaCion
Coupling
DlazocizaCion
Coupling
Dlazocizaclon
Coupling
DlazocizaCion
Coupling
DlazocizaCion
Coupling
DlazocizaCion
Coupling
Dlnzoclzacion
Coupling
Atfdociatud Waste Total
Wnsces TriMiCir.ont Production Uses Rofen
V,^C£r: inorganic
sales -
VnCi'r: inorganic
sales
W.itor: inorganic
sales
Water: inorganic -- 35.5 (7S)- 2)330
salts 19"
Vater: inorganic ~
salts
Water: Inorganic 42-3 (93)- _
sales 1973
Water: inorganic -
sales
Water: Inorganic ~ 818 (1.799)-
salcs 1973
Wacer: Inorganic 10.9 (24)-
salts 1973
Water: inorganic . -
salts
Water: inorganic * -
salts
Water: Inorganic ~
sales
Water: Inorganic
salts
Water: Inorganic
salts
salts
Water: inorganic -
sales
Water: inorganic
salts
Wacer: inorganic 24.1 (53)-
sales 1973
Water: inorganic
sales
Water: inorganic
salts
Water: Inorganic __ .
salts
Water: inorganic
salts
Vater: Inorganic
salts
Wnter: inorganic 2)330,
salts
Water: Inorganic 69.6 (153)- .
salts 1973
-------
te°
m
^r
128
129
130
131
132
133
134
135
136
137
138
139
k
P40
141
142
143
144
145
146
147
148
149
150
151
152
153
154
Ccapound
Name and
Formula
C1U720 Acid Rod 14
CI14830 Calcium Pigment
Red 54
CI14855 Verdant Blue' 9
CI14870 >tordant Brown 15
CI14880 Acid Blue 158
CI15050 Acid Blue 158
C115075 Direct Red 20
CI15510 Acid Orange 7
Lake Figment
Orange 17
D&C Orange 4
CI15575 Acid Orange 8
CI15585 Sodium Pigment
Red 53
" Barium Pigment
Red 53
" DiC Red 9
D&C Red 8
CI15620 Acid Red 88
CT15630 D&C Red 10
" DiC Red 13
" D&C Red 12
D&C Red 11
" Sodium Pigaent
.. Red 49
" Calcium Pigment
Red 49
* Barium Pigmenc
Red 49
CH5670 Mordant Violet 5
CU5705 Mordant Black 17
CI15710 Mordant Black 1
CU5711 Acid Black 52
n-J3
TAIlli: P-3. (Continued)
Chen. Abstr.
Ri>Elatry No. Oral Toxlctty, Toxic Hnznrd R.-itltu;
IWLN) L'J50' "Z'k* Aciito Clirnnlc ToxlcoloRV TLV
003567699 ' L050:910 mg/kg
(LfieiJ BSUQ lor-rat
ENUN- CL66J
BQ ESWJ i-NA-
2}
. '
003624688
008006028
-- -- --
_ _ _ _ _
005350737 "
OOOJ33965
000633965* "~ ~
000633965 '
005350852
002092560
002092560* /
024777239
002092560
001653566
001248186
005371671 '
001103334
001103395
001248186
001103395
001103384 --
002092559 --
002533854
003613584 .
OOS6 10640
^m
CurclnORei^J
.
--
--
~
".
.
-------
Sources of
^Co.np.nmJ
__
Process
4
4
' 4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Dlazotizatlon
Coupling
Dlazotizatlon
Coupling
Diazotization
Coupling
Dlazotizatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlazotizatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlazotizatlon
Coupling
Diazotization
Coupling
Diazoclzation
Coupling
Diazotization
Coupling
Dlnzotization
Coupling
Diazotization
Coupling
Diazotlzatlcn
Coupling
Assoctnt ud
Water;
salts
Water;
salts
salts
Water:
salts
Water:
salts
Water:
salts
salts
Water:
salts
Water:
salts
Water;
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water;
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
salts
inorganic
Inorganic
inorganic
Inorganic
Inorganic
Inorganic
Inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inoig.nnic
Wastj Total
Tr>'orr.vnt Production Usoa Ro^ri'nce^^k
60.0(13.')- 2)330.777
1973
34.6 (76)-' '
1973
_ _ '
}540 (1,188)- " "~
1973
257 (565)- _ " _
1973
2.27 <5)-
1973
125 (275)-
1973
1445 (3,179)-
1973
.
458 (1,008)-
1973
__ __
1.8 (4)-
1973
6.3 (13)-
1973
634 Cl. 395)-
1973
1997 (4,393)-
1973
381 (!«8)-
1973
-------
B-75
TAIILE B-3. (Continued)
155
156
157
153
159
160
161
162
163
164
165
166
167
>
169
170
171
172
173
174
175
176
-177
178
179
180
181
Com pound
N.~tmc and
Ko rmu 1 n
CI15800 Pigment Brown 5
" D4C Red 31
" Pigment Red 64
C115820 Pigaent Red 55
CI15825 Pigaenc Red 58
CI15826 Pigment Red 77
CI15850 Calcium Pignent
Red 57
" DiC Red 7
O&C'R'ed 6
CI15860 Pigment Red 52
CI15365 Pigment Red 48
CI15380 Pigment Red 63
D&C Red 34
CI15970 Acid Orange 12
CI15985 DSC Yellov 6
FD4C Yellov 5
CI15995 Acid Orange 31
CI16055 Acid Violet 56
CI16105 Lake Pigaent
Red 60
" Mordant Red 9
CI16150 Acid Red 26
CI16180 Acid Red 17
CI16135 Acid Red 27
» . FD&C Red 2
DSC Red 2
CI16230 Acid OranRe 10
Ctld255 Acid 'fed 18
Chem. Abstr.
RexlJtrv No. Oral Toxlctty. To
-------
Sources of
^^ CuropounJ
«
-
~
-
~
»
Process
No.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Pr.-vi-sa
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotizaelon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
DiazotJzacion
Coupling
Diazotization
Coupling
Diazotization
Coupliag
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlazotiration
Coupling
Diazotl/atlon
Couplir.g
Diazotization
Coupling
Diazoclzation
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Plazotlzatlon
Coupling
Dlozotlzation
Coupling
Dlaxoclzatton
Coupling
Dlazotlzacion
Coupling
AsHoclaCed Waste
Mn.
-------
fe
w.
187
1S3
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
Compound
Name nnd
Formula
CD 6260 Acid Violet 53
" Solvent Red 35
CI16500 Mordant Black 9
CI16575 .Veld Red 176
CI16580 Acid Violet 3
CI!6600 Acid Violet 6
CI17025 Acid Violet 1
CI17045 Acid Red 37
CIJ7065 Acid Red 32
CI17200 Acid Red 33
» . DSC Red 33
CI17235 Mordant Craen 36
.CI17590 Mordant Brown 40
CI17755 Acid Red 137
CI17757 Reactive
Orange 16
CI17820 Direct Red 123
CI1790S Reactive Red 8
CI17916 Reactive Black 1
CI17995 Acid Red 133
CI18050 Acid Red 1
CU8055 Acid Violet 7
CI1S065 Acid Red 35
CI18073 Acid Red 133
CI18075 Acid Violet 12
CI10096 Reactive
Violet 4
C118097 Ruactlve
Violet 5
CI18105 Reactive Red 4
CI1S110 Acid Red 106
CI18153 Reactive Rod 1
E-77
TAHU: P-3. (Continued)
Chen. AbHtr.
Registry No. Oral Toxlclty, Toxic ll.iznrd Ratlm-. .
IWLN) l~'jO' **'*>» Acnti- Chronic Toxtcoloqv TLV Cart Inc.- ell
(BL6frJ ESWO 4-NA- 4)
' -- --
000548S01 __'__
OQ'632477
001681603 .
004197095
_ _
005360072
_-
003567666
003567666 _ i_
00376961.7 _ _ _
_ _ _
006222635 ---.-*
._
-~
025409365 ~ _ _
01:236770
006417363 ' -
003734676
00^321691 ' .
006441936
__ __ _ _
__ ' ' "
012226339 -- . " ~ ~
01S623662 -
.
017752851 . --
-------
B-7a
Sources of Process
^ Compound No.
_ ' A
« q
4
4
' 4
4
4
4
4
4
4
*.
4
4
4
4
4
4
4
4
4
4
* 4
. 4
4
-~ 4
4
4
4
Process
Coupling
Dlazotlzuclon
Coupling
DlazoclzuCton
Couoling
Dlazotlzacion
Coupling
Diazocizatlon
Coupling
Diazotlzation
Coupling
Diazocizacion
Coupling
Coupling
Diazotizacloa
Coupling
Diazocizacion
Coupling
Diazotlzation
Coupling
Diazotization
Coupling
Diazotizacion
Coupling
Diazotlzation
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
D la zo c 1 za C ion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Dlazoclzatioa
Coupling
Dlazocizatlon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazoelzation
Coupling
Diazotization
Coupling
Dlozuclzaclon
Coupling
Dtrr/oclzation
Coupling
; Dinzottzatlon
Coupling
As
salts
Water:
salts
Water:
sales
Wacer:
sales
Water:
sales
Wacer:
salts
Water:
salts
salts
Wacer:
sales
Wacer:
salts
Water:
salts
Water:
salts
Water:
salts
Water;
salts
Water:
salts
Water:
sales
Water:
sales
sales
WaCcr:
sales
Vacer:
sales
Waeer:
sales
Wacer:
salts
Waeer:
sales
Uaccr:
sales
Water:
sales
Water;
salts
W.icer:
anlts
Wa_eer;
gales
Water:
sales
.icclnied Ku«tu Total
Wa>lr:* Trratnonc Product Ion
inorganic
Inorganic
inorganic
Inorganic 17.7 (39)-
1973
inorganic
inorganic
inorganic 28.6 (63)-
1973
inorganic
inorganic
inorganic -
inorganic
inorganic .
Inorganic 59.1 (130)-
1973
Inorganic
inorganic
inorganic
Inorganic
inorganic 207 (455)-
1973
inorganic 90 (193)-
1973
inorganic
inorganic
Inorganic -
inorganic
inorganic
Inorganic
inorr..-.nic
Inorganic
Uses Ri.'f«?rcnci
. _
-
_ _
« __
» -_
_
_ _
«._
_
_ _
__ '
__
__
«
,
- -,
-------
B-7')
TAI1LE B-3. (Continued)
IL
211
21?
213
214
215
216
217
218
219
220
221
222
223
>24
225
226
227
228
229
230
231
232
233
234
235
236
237
|233
239
Compound
Name and
Pormiln
CI13159 Seantivo Red 3
CUS160 Mordant Black 33
CI18J.65 AciJ Bloc'* 60
CI1S690 Acid Yellow 121
CI1S695 Acid Yellow 4
CI18710 Mordant
Yellow 30
CI18732 Acid Oranjw 60
CI18740 Acid Orange 72
CI1S745 Acid Orange 74
. " Solvent Orange 5
CI18760 Mordant Red 7
CI18761 Acid Red 201
CT18ROO Acid Red 133
CI18810 Acid Red 186
CI1S820 Acid Yellow 11
CI18S21 Mordant
Yellow 8
CI18835 Acid Yellow 25
CI18850 Acid Yellow 25
CI18870 Acid Orange 76
CI18890 Acid Yellow 34
CI18900 Acid Yellow 29
C118940 Mordant
Orange 4
CIJ8950 Acid Yellow 40
CI18960 Acid Yellow 14
CIJ8965 Acid YelJov 17
CI18990 Reactive
Yellow 13
CI19010 Acid Yellow 54
CU914Q Acid Yellow 23
DJ.C Yellow 5
Chcca. Atistr*
Registry No*
023:11474
000l>il9.'.9
012218950
014904519
010127772
010127272*
003618631
OOMOJ317
052677448
006359826
006359359
025739677
.
006359917
006359962
006372969
006359984
010127056
001934210
001934210*
Ornl Toxlc.lty. Toxic I!n:nn1 Racine
DO' u^' ^ Acuto nucule Toxicology
_ --
-_
. _
' . _
' _ _
_
v|
' _ _ _
_ ..
_ _
_ _ _
_
_ _
_
_ _ _
~ -
_ _
TLV Cnrcl
_
.
_
.
'
.-
-------
K-tift
Source* of
ConrvunJ
K
_
_*
_
_
_
__
_ _
__
Pro.- us >
K-'.
4
4
4
4
4
4
4
4
4
4 .
4
4
4
4
^
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Dlazot izacion
Coupling
Diazoclzaelon
Coupling
Dlazotizacica
Coupling
Diazotizaticn
Coupling
Dlazotizaelon
Coupling
Dlaz6cizacion
Coupling
DiazocizaCica
Coupling
Diazoclzatlon
Coupling
Dlazotization
Coupling
Diazotizatioa
Coupling
Dlazotlzaclon
Coupling
Diazocizacion
Coupling
Dlazotizaclon
Coupling
Dlazotlzaclon
Coupling
Coupling
Diazotlzation
Coupling
Dlazotlzaclon
Coupling
Dlazoclzaticn
Coupling
Dlazotlzaclon
Coupling
Dlazoclzaclon
Coupling
Dlazoclzaclon
Coupling
Dlazetizatton
Coupling
Diazoclzatlon
Coupling
Dlazoclzaclon
Coupling
Dlazoclzaclon
Coupling .
Dlazotlzatlon
Coupling
Dlazoclzaclon
Coupl Ing
Dlnzoctzacion
Coupling
Dtazotizntion
Coupling
AS!
V
Water:
Hairs
Wjcer:
sales
Water:
sales
Water;
salts
Water:
sales
Water:
salts
Water:
salts
Water:
salts
Water:
sales
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Vater:
sales
salts
Water:
sales
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water;
salts
U.iter:
salts
W.-itec;
salts
Water:
salts
Water:
salts
Water;
u-iitu
loclnti-d Wait?
JosFc* Tn-ntr.-.cnt
Inorgonlc
inor&mlc
Inorganic
Inorganic
Inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic .
InorRnntc
Total
Product ton
~
148 (325)-
1973
40.0 (88)-
1973
__
__-.
33.2 (73)-
1973
_
._
40.0 (38)-
1973
_
..
117 (2S3)-
1973
149. (327)-
1973
26.3 (58)-
1971
287 (631)-
1973
Uses Ri;f«r<
_
_..
« *.
__
^_ _
* ._
__
__
..
» _*
_
_
__ __
^.
» ..
_ _
.. _..
_
_. ^.
_ _
-------
B-B1
TAIJUC B-3. (CdiUlnued)
ko
W"3
240
241
242
243
244
245
246
247
248
249
250
251
252
t>
254
255
256
257
258
259
260
261
262
263
264
265
266
1267
268
Compound
Numo nnil
F.'rniiln
FD4C Yellow 5
CU9350 Mordant Dye 1
CI19351 AcIJ Red 179
CI19540 Direct Yellow 9
CI19555 Direct Yellow 28
CI19556 Direct Yellow 29
CI19500 Mordant Brown 21
CI20040 PigMnt
Tellow 16
C120110 Mordant Brown 1
CI20150 Mordant Brown 18
C120170 Acid Orange 24
C120195 Acid Brown 14
CI20440 Acid Green 19
CI20460 Acid Blue 29
CI20470 Acid Black 1
CI20480 Acid Black 41
CI20495 Acid Green 20
C120505 Reactive Black 5
C121000 Basic Brown 1
CI21010 Basic Brown 4
n Pigment Broun 3
ii Solvent Brown 12
C121030 Basic Brown 2
CI21090 Pigaent
Yellow 12
CI21095 Plgaent
Yellow 14
CI21096 Pigment
Yellow 55
CI2UOO Pl^nt
Yellow 13
CI21105 Plsjiuint
Yellow 17
CI21108 Plitmrne
Yellow 83
Chum. Abstr.
Registry No.
(VL.N1
001931210
001829001
008005729
006537662
006232515
005979282
003654156
-
001320076
005350340
000106448
005850395
012225251
010114585
005421669
005421669*
005421669*
006358856
005463757
005102830
004531491
005^,7157
Ornl ToNlslty. Toxic Il:iznrd Rntini-
LO-iQ, nv'«S Acuto Chrunlc
-_
_-
_-
_
_
.
~
, --
_
_
_
.
_ _
-_
_-
_.
_
_
_
TcxlcoJoKv
~
~
.
--
TLV
-
--
~
--
Carclnou
.
--
.
'
~
--
-r
-------
Sources of
1 ComjvtmJ
_
__
,_. *
^_,
,__,
__
,_,
^_
_.
T
. .
--
_
l T
,__
_
-
Process
No.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
^
4
4
4
4
4
4
i
Process
Dlazoclzjcion
Coupling
Diazocizacion
Coupling
Dlazoclzacioa
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocization
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Diazoelzacion
Coupling
DlazoclzaCloa
Coupling
Diazocizatioa
Coupling
Dlazotlzacion
Coupling
Dlazoclzacioa
Coupling
Coupling
Diaro-tlzation
Coupling
Diazotizacioa
Coupling
Diazoelzacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Dlnzociznclon
Coupling
At:
I
Water:
salrs
V.uer:
salts
Water;
sales
Water:
sales
Water:
sales
Wacer:
sales
Vacer:
sales
Vacer:
sales
Vater:
sales
Vacer:
sales
Uacer:
sales
Water:
sales
Wacer:
sales
"acer;
sales
Vacer:
sales
Vacer:
sales
Vacer:
salts
Wacer:
sales
Water:
sales
Vater:
sales
Vater:
salts
Vater:.
salts
sales
Vacer:
salts
Water:
salts
Wator:
sales
V.iter:
sales
v.iccr:
sales
Wntc^r:
snlctf
J.ISti'S
inorganic
lnorg:mie
inorgiinic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
Inorganic
inorganic
Watte Tocnl
Tr.'.ltttPnt Production Vf.ct
*26 (1.378)-
1973
_
93.2(205)-
1973
._
' '
14.6 (32)-
1973
. -
210 (461)-
1973
127 (280)-
1973
_
~~
_ 357 (786)- _ -
1973
10.9 (24)-
1973
_ v __
59 (130)- __
1973
235 (518).
1973
__
9.1 (20)-
1973
_ 3,817 (8.393)- _
1973
1,225 (2,694)-
1973
261 (574)-
1973 '
Rofcr.'nccs
_
_
_»
^_
_ ^
_
:
_
__
__
__
r_
._
.
.
-------
It 031
So. _
269
270
271
272
273
274
275
276
277
273
279
280
281
282
233
234
235
236
237
288
239
290
291
292
293
294
295
296
297
Compound
Naiiu' and
Fonr-uln
C121110 Plgaent
Orange 13
CI21U5 Pigment
Orange 34
CI21120 Pigment Red 33
CI21130 Pigaent
Orange 15
CI21150 Pigsent
Orange 16
CI21165 Plgoent
Orange 14
CI211SO Pigment Blue 25
CI21200 Pigaent Red 41
C121230 Solvent
Yellow 29
C121240 Solvent
Yellow 30
CI21250 Solvent Red 22
CI22120 Direct Red 23
CI22130 Direct Orange S
CI22140 Direct Orange 8
CI22145 Direct Red 10
CI22155 Direct Red 13
CI22165 Direct Dye 0
CI22195 Acid Orange 45
CI22240 Direct Red 37
CI22245 Acid Red 85
C122310 Direct Red 1
C122311 Direct Brovn 2
CI22345 Direct Bro«\ 59
CI22370 Direct Orange 1
CI22375 Direct Orange 1
CI22410 Direct fellow 20
CI22430 Direct Orange 1
CI22460 Direct Violet 27
C122480 Direct Violet 22
B-83 -,
TAULE 11-3. (Continued)
Chen. Abstr.
Ri'Eistrv No. Ornl ToxltiltV. Toxic Knz.inl Rnritx
(Wl.N) LU50- "'I;/ kB Acute Chronic Toxicology Tl.V
003520727
006358873
_ -_
-----
024876322
006505299
010127034
003321106
006706758 .
0005735SO TDLo:80 ng/kg/
(1.66 J B2 ESWQ . (SDpreg) TFX:TER
CNUNR D2 ' unk-rat
&-NA- 2) . LD50:190 eg/kg
Ivn-rat
002429701 -- .
_ _
002429701
001937355
_ _ _. -
0024298ns
~
003567655
002429847 .
002429825
no*,, - - -
_ _ _
.. _- _
_ _ _
' . _ . _ ' _
OOG42f,671 '
j
'
. ._
~
.
--
.
.«.
-------
B-bi
Sources of
Compound
r
-
'
Process
No.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Dlozotlzatlon
Coupling
Dlazoclzatlon
Coupling
Dlazotlzatlon
Coupling
Dlazotizution
Coupling
Diazotlzatlon
Coupling
Dlazoclzatlon
Coupling
Dlazotlzatloa
Coupling
Dlazotizatlon
Coupling
Dlazotlzatioo
Coupling
Dlazoclzatloa
Coupling
Diazotlzation
Coupling
Diazotlzatloo
Coupling
Dlazoclzatloa
Coupling
Dlazocizatios
Coupling
Diazotizatlon
Coupling
Dlazoclzatlon
Coupling
Dlazotizatlon
Coupling
Dlazoclzaclon
Coupling
Dlazoclzaclon
Coupling
DiazoclzaCioa
Coupling
Dlazocizatioa
Coupling
Diazocizaclon
Coupling
Dlazotlzatlon
Coupling
Diazocizaclon
Coupling
Ola zodiac Ion
Coupling
DiazoclzaCioa
Coupling
Diazocizacion
Coupling
Dlazoclxtion
Coupling
Dln*otl *.it Ion
Coupling
Associated Waste
W.-istt-s Treatment
Water:
sales
Water:
sales
WaCer:
salts
WaCer:
sales
Water:
sales
WaCer:
salts
Wacer:
salts
Water:
salts
Water:
salts
Wacer:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water:
salts
Water;
sales
W/ucr:
Bafts
Water;
sales
Wjuor^:
sal t«
inorganic
Inorganic
Inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
Inorganic
Inorganic
Inorganic
inorganic
Inorganic
Inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
inorganic
inorp.inic
inarg.inic
inorganic -
lotnl
Product ion
149 (327)-
1973
40.9 (90)-
1973
171 (377)-
1973
--
136 (300)-
1973
60.0 (1321-
1973
60.5 (133>-
1973
76.8 (169)-
1973
90.9 (2001-
1973
67.3 U48)-
197T
Uses References
_
--
_.
.
'
~
-------
Item
No,
298
.299
300
301
302
303
304
305
306
307
303
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
Compound
Name and
Formula
CI22570 Direct Violet 1
C122590 Direct Blue 2
C122370 Acid Orange 63
C122S80 Mordant
Yellow :6
CI22390 Acid Red 97
CI22895 Acid Orange 56
CI22910 Acid Yellow 42
CI23050 Direct Red 46
CI23155 Direct Blue 98
CI23266 Acid Red 111
CI232S5 Acid Red 99
C123365 Direct Orange 6
C123370 Direct Orange 10
CI23375 Direct Orange 6
C123500 Direct Jed 2
CI23530 Direct ied 39
CI23635 Acid Red 114
CI23790 Direct Blue 25
CI23350 Direct Blue 14
CI23900 Acid Yellow 44
CI23910 Acid Red 89
CI24065 Direct Slue 136
CI24100 Direct Red 7
CI24125 Acid Red 128
C124140 Direct Blue 8
CI24175 Direct Blue 151
C124280 Direct Blue 22
CI24/.00 Direct 31ne 15
CI2'.401 Direct Blue 2M
1I-S5
TABU P-3. (Continued)
Chuc, Abntr.
Registry No, Or.il Toxlclly, Toxic il.iinrJ Katlni; ^^k
. (VLS) LU50> "W/k.l Acutf Clu-onlo Toxtcolosv TI.V r.^-l ,..<^^B
002536609 -- --
0024:9734
006232491
_ _ _ _ _
_ _ _ _ _
006375559 --
_ _ ., _ _ _ _
006656037 __
006358572
003701404 --
_ _ _
_
_ . _ _ _
000992596 . -
006459945 _ _ _
002150541 -- --
000072571 TDLo:25 mg/kg/ ~ TDLo:825 tng/Vg/
(L65J BQ Dr..'Q (8Dpreg),TFX:TER 65WI, TFX:CAR
HSVJ 1Z CtilWS scu-ous scu-rat
B D- 2 &-NA- LD50:267 ng/kg
4) SCU-CDUS
002429757
006472500
_ _ _ _ ' _ _
002368759
_ _- _- .
n<12'.29712 . ' __
oouuw
002J86574
002429745
_ _
-------
B-B6
Sources of
Compound
_-
~
.
~"~
--
Process
No. . .
4
4
. 4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Dlazoclnaclon
Coupling
Dlazotlzacion
Coupling
Diazo:i:aclon
Coupling
Diazocizacion
Coupling
Diazoclzatlon
Coupling
Diazoeizaeion
Coupling
Diazo-clzatlon
Coupling
Diazocization
Coupling
Diazoeizaeion
Coupling
Diazocizacion
Coupling
Diazocization
Coupling
Dlazoeizacioa
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazotization
Coupling
DlazotizaCion
Coupling
Diazocizacion
Coupling
uiazocization
Coupling
Diazocization
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Didzoclzation
Coupling
Diazocizacion
Coupling
Dlazocizrtclon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
bl.ir.o.1: Iz.'if Ion
Coupl Ing
Associated
Wnsti'*
Water:
sales
Water;
salts
W-icer:
sales
Wacer:
sales
Wacer:
sales
Wacer:
sales
Wacer:
sales
Water:
sales
Water:
sales
Water:
salts
Water:
sales
Water:
sales
Wacer:
sales
Water:
sales
Wacet:
sales
Wacer:
salts
Water:
sales
Water:
salts
Water:
salts
Wacer:
sales
Wacer:
salts
Water:
salts
Wacer:
sales
Water:
sales
Water:
sales
W^tor:
sales
Wo_c_cr:
sal en
Water:
salts
Water:
till C'l
Inorganic
Inorganic
Inorganic
inorganic
inorganic
inorgan ic
inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
Waste TOCJ!
Trfotr.cnr Production
-_ 540 (1.188)-
1973
'
29.6 (65)-
1973
152 (334)-
1973 .
61.4 (135)-
1973
.
96.4 (212)-
1973
_ 56.8 (125)-
1973
- 255 (560)-
1973
22.3 (49)-
1973
"
'
20.0 (44)-
1973
660 fl,472)-
t<171
Usos Rofcronces
'
__ _
_ _
.
_ _
_ _
'
.
_ _
_ _
2)330. 774
_
. '
_
.
-
-------
F.-87
TAI'.I.K l!-3. (Coiitlnuvd)
Item
No.
327
328
329
330
331
332
333
334
335
336
337
333
339
340
341
342
343
344
345
346
347
343
349
350
351
352
353
354
355
30 Acid Black 26
Chun. Al>str.
Registry No. . Oral Toxicltv.
(VLN) LD50' mS'kK'
002610051
016143796
006459694
003051114
002$ 70328
_
_. _
_ _
_ '
002329427
002329438
007198994
_ _
006250233
000385869
000085836
(L63J BNUXR B
DNCSTl B&S CQ)
004477796
001320065
004197255 . --
.
003351051
003071736
003529019
006406322
003554270
004196990
Toxic lln:nrd Rjiclivv-.
AcuCv Clirpnli: Toxlcolorv TLV
_-
_ _ .
- . "
_
_
_ _ _
_ _
_ _ _
_ _ _ - _ .
_ _ _
_ _
_
_
.
.
_ _ _
_ _
_
_ _ _
.-
_
TDLo:512 mg/kg/
58WI, TFX:CAS
ecu-roc
-------
Sourc
-------
ItCUl
SOi
357
358
359
360
361
352
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
335
Cirapotmd
N,iac and
Formula
CI27075
C127200
C127290
C127680
CI27700
C127720
C127855
CI27885
CI27905
C127925
CI28160
CI23210
C128215
C128230
CI28240
CI28255
CI28280
CI28360
CI29000
CI29005
CI29025
CI29060
CI29055
CI29090
CI29100
CI29105
CI29110
C129120
CI29.125
B-89
TAUIJ; H-3. (Continued)
Chcm. Abstr.
Registry No. Oral Toxlelty, Toxic N.irnrd Rntlm;
(VIA) U)50- "i-'kS Acute Gironiu Toxlcoloqv TLV Curclnocc
Acid Black 26
Acid Red 115 006226808 --
Acid Re
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
d 73 005413752 ~
Red 16 006227027 ~
Black 17 002945962
Black 51 034977634 _ _ _ _ _
Violet 7
Violet 9 006227141
Violet 51 005489770 _ - .
Blue 67 003354970
Red 81 002610119 .
Rad 153
Red 127
Red 117 .
Slack 127
Oraage 74 005104569 .
Creeu 33
Red 152
Yellow 44
Yellow 41
Yellow 50 003214479
Yellow 34 006420333 . ~
Red 79 001937344
Orange 33 . '
Red 31 005001729
Violet 14
Red 149 '
VIolot 66 --
Violet 48 ~ .
-------
B-W
Sources of
Compound
.
-
Procctj
N\>.
4
4
4
' 4
4
4
4
4
.4
4
4
4
4
4
4
4
4
4
4 .
4
4
4
4
4
4
4
4
4
4
Pr«e«
Diazocizacion
Coupling
Diazoclzacion
Coupling
Dlnzocizacioa
Coupling
Diazoclzacioa
Coupling
Dlazoclzaeloa
Coupling
Diaz6clzacion
Coupling
Diazocizacion
Coupling
Diazocizacioa
Coupling
Diazocizacloa
Coupling
Diazocizacion
Coupling
Diazocizacloa
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
Diazoclzacioa
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazotlzacion
Coupling
Diazocizacion
Coupling
Diazoclzacioa
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
DiazoChZaclon
Coupling
Dlazoclzaclon
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Dlor.ocizaclon
Coupling
As
i
Vac or:
s-ilts
V.i tor;
sales
Vaccr;
sales
Water:
sales
Vjeer:
sales
Vacer:
sales
Vaeer:
sales
Wacer:
sales
Water;
salts
Vater;
salts
Water;
sales
Vacer:
salts
Water:
sales
Vater:
salts
Vater:
sales
Wacer:
sales
Uacer:
sales
Wacer:
sales
Vacer:
sales
Waeer:
sales
Water:
sales
Wacer:
sales
Wacer;
sales
U.i'cer:
salts
Vaccr:
sales
v.icer:
sales
V.Ttcr;
sales
V.iccr;
sales
iiccr:
BjUB
GOciaCctl Waste
U'.istt.':; Trvntr.LM-. c
Inorganic
Inorganic
inorganic
inorganic
inorganic ~
inorganle
Inorganic
inorganic .
inorganic
Inorganic
Inorganic
inorganic
Inorganic
inorganic '
inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic .
inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
Inorganic
Total
Product ton
23.6 (52)
1973
119 (261)- '
1973
41.4 (91)-
1973
68.2 (130)-
1973
5.5 (12)-
1973
337 (742)-
1973
"
459 (1.009)-
1973
113 (248)-
1973
.
40.9 (90)-
1973
20.0 (44)
1973
~~
f'.fS
~
. _
'
^foroncts
_ .
.
.
~
-------
Item
So.
386
387
338
339
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
403
409
410
411
412
413
414
Compound
Name nnd
F.' rim la
CI29150
CI29155
CI29156
CI29160
CI29165
CI29166
CI29175
CI29180
CI29185
CI29190
CI29200
CI29210
CI29225
C130015
CI30045
CI30120
CI30140
CI30145
CI30220
CI30235
CI30245
CI30280
CI30295
CI3031S
CI31560
CI31565
CI31575
C131600
C1U665
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Direct
Dlruct
B-91
TAIUi: il-3. (Coi\clnu«-J)
Clicm. Abctr,
Registry No. Oval Toxlclty. Toxic Hflzitn] Rntliv.-
C-LV) LD50- n*'k>' Acute ChrmiU Toxlvolor.v TLV
Orange 24 0036:6366
Orange 29 006420402 ~
Orange 102
Ked 23 003441143
Red 4 006470413 __ _
Brown 112 .
Red 62 ' -- .
Red 73 '
Red 24 006420446
Red 26 003687807 '
Red 72
Red 122 006420468
Sed 83 015418163 .
Black 78
Brown 1 003311710
Brown 154 006360549
Brovn 6 002293803
Brovn 95 016071S66
Stem 39
Slack 38 001937377 '
Black 4 002429336
Green 1 003626236
Creen 6 004335095
Green 8 005422173
Black 9
Slack 9
Black 2
Black 80 003003698
Black 35 --
-------
Source of
Conr.'dr.J
"
"
'
_
--
ttOiCSi
N.>.
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Dlazocizatioa
Coupling
Dla zodiac Ion
Coupling
Dlazoclzacioa
Coupling
Dlazoclzaelca
Coupling
Diazotizatioa
Coupling
Diazoctzatloa
Coupling
Diazoclzaclea
Coupling
Diazocizacioa
Coupling
Diazotizatioa
Coupling
Diazociiacloa
Coupling
DiazoclzaCioa
Coupling
DiazoclzaCioa
Coupling
Diazo:lzacioa
Coupling
Diazocizatloa
Coupling
Dlazoeizacloa
Coupling
Diazocizacioa
Coupling
Diazocizacioa
Coupling
Diazocizatloa
Coupling
Dlazocizacioa
Coupling
Diazocizacioa
Coupling
Dlazocizacioa
Coupling
Diazocizacioa
Coupling
Dlazocizacioa
Coupling
Diazoclzaeioa
Coupling
Dlazocizacioa
Coupling
Dlaiocizacion
Coupling
Diazocizacion
Coupling
Dlazoclzatlca
Coupling
Dinzoclza ticn
. Coupling
. Assocl.itcU linsti!
V.iiti'it Troal-si'iit
V.i cor:
Hairs
Vjtcr;
salts
Voter;
sales
Vacer;
salts
Vatec;
sales
Vacer:
salts
Vater:
sales
Vacer:
salts
Vater:
sales
Vater:
sales
Vacer;
sales
Vaeer;
sales
Vacer:
sales
Vater:
sales
Vater:
sales
Vacer:
sales
Vater:
sales
Vater:
sales
Vacer:
sales
Vater:
sales
Vacer:
sales
Vater:
salts
Vater:
salts
Vater:
salts
.Vater:
salts
'-.iter;
salts
Water;
salts
V.i tor:
aulcu
ili.1I1
sails
inorganic
inorganic
inorganic
inorganic
inorganic
ino rganlc
inorganic
inorganic
inorganic --
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic ~
inorganlc
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
inorganic
inorganic
1 no n;anlc
Total
ProJuctl.in Us.-s
43.2 (9S)-
197J
117 (2')3)- ' _
197J
115 (252)-
1973
'
182(400)-
1973
98.6 (2171-
1973
165 (362)-
1973
_
74.6 (164)-
1973
~
.
~ ' ~
258 (567)-
1973
3.065 (6.743)-
1973
75.0 (165V .
197T
85.9 (189)- _
1973
~ «
313 (M)8)-
1973 .
Rofcrcncci
.
'
.
--
-------
Icon
So,
115
416
417
413
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
433
439
440
441
442
443
Compound
N.uai; and
F.-rrr.ilo
CI31930 Direct Blue. 26
CI34010 Direct Blue 126
C134015 Direct Srovn 32
CI34045 Direct Green 26
CI34085 Direct Blue 120
CI34Q90 Direct Blue 120A
C134140 Direct Blue 71
C134146 Direct Blue 74
CI34X70 Direct Black 56
CI34200 Direct Blue 78
CI34215 Direct Blue 81
CI34220 Direct Blue 75
CI34260 Direct Green 51
CI35005 Direct Brown 44
CI352S5 Direct Black 19
CI35435 Direct Black 22
CI35660 Direct Brown 31
CI35760 Direct Red 84
CI35730 Direct Red 80
CI35790 Direct Red 32
CI35870 Direct Black 75
CI36200 Direct Broun 106
CI36300 Direct Brown 74
C137000 Sase Azoic
Oiazoic 44 .
" Salt Aiotc
Dlazoic 44
CI37005 Salt Azoic
Dlazoic 2
" Bj3c Azoic
Dlazoic 2
C137010 3ase Azoic
Diazolc 3
" Salt Azote
D1-17.OLC 3
B-93
TAUI£ 11-3. (Continued)
Choc. Abxtr.
Registry No. Or.il Toxlqlty, Toxic lln::nr
-------
Sources of
Conijvunil
;
' .
'
«
«
'
.
_
Process
' NV. .
4
'.. 4
4
'" 4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Diazotization
Coupling
Diazotization
Coupling
Dinzoclzaeloo.
. Coupling
Diazotizacion
Coupling
Diazotization
Coupling
Diazotizacion
Coupling
Diazotlzaclon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlazoclzatioa
Coupling
Dlazotizatioo
Coupling
Diazotizacion
Coupling
Dlazocizatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Dlazotlzacloa
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Diazotization
Coupling
Dlazocization
Coupling
Dlazotlzatlor.
Coupling
Diazotizacion
Coupling
Dlazocization
Coupling
Diazoclzaclon
Coupling
Dlazotli.lt Ion
Coupl Ing
Associated
Wastv.'i
Water;
salrs
W.i cor:
salts
Water:
salts
Water;
salts
Water:
sales
Water!
salts
Water:
salts
Water:
sales
Water:
salts
Water:
salts
Water!
salts
Water:
salts
Wacer:
salts
'-'ater:
sales
WaCer:
sales
Water;
sales
Water:
salts
Water;
sales
Water:
' salts
Wacer:
salts
Water:
salts
Water;
salts
Water;
salts
W.iter:
salts
Water:
salts
W.icor:
salts
Water;
salts
W.itcr:
sales
VMter:
Inorganic
Inorganic
inorganic
Inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic
Inorganic
Inorganic
inorganic
inorganic
Inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
Inorganic
Inorganic
inorganic
Inorganic
Inorganic
Inorganic
inorganic
Inorganic
Wniito Total
Tr.'ntciont Production Usos
42.3 (93)- _
1973
'
59.6 (131)-
, 1973
_ 47.7 (105)- _
1973
_i
__
-
(475)-
1973
39.6 (87)-
1973
' :
297 (653)-
1973
_
--
_ 1VI (337)- _
1973
Rcfcroncos
.
.
~
'
.
-- .
-------
II-'JS
TABLE b-3. (ContltiucJ)
It en
No.
Compound
Name and
Formula
Chen. Abstr.
Rcjiiitry No.
(WLN)
Or:il
LlV
I°!»-
TcixK- \(a~
A i- iiu-
ii n! R:iclnt;
Chronic
TostcoloKY
TLV
,,,,,
444
Azoic Broun 31
445
Azoic Orange 3
446
447
448
449
450
451
452
453
454
455
456
457
458
CI37025 Salt Azoic
Diazoic 6
CI37035 Salt 'Azoic
Dlaiolc 37
CI37040 Sale Azoic
Diazoic 9
CI37050 Azoic Orange 10
Sale Azoic
Diazoic 49
CI37080 Base Azoic
Dlazolc 46
CI37035 Base Azoic
Dlazolc 11
Salt Azoic
Dlazolc 11
CI37090 Salt Azoic
Dlazolc 32
" . "Base Azoic
Dlazolc 32
» Azoic Red 1
Azoic Yellw 3
" Azoic Red 6
OOOOS3744
(7.R S»0
000100016
(ZR DNW)
000039634
(ZR DG BtWZR
DC BMW)
000121505
(ZR &G
EXFFF)
003165933
(ZR DC B &GH)
003165933*
__
535 orl-rnt
3249 orl-rae
-~
' '
LDLo:40mg/kg
Ivn-nan
LDsn:63 m;
USOS air:TWA 1
ppo
LDLo:100 ng/kg
ipr-mus
U>50:560 mg/kg
lor-rat
459
Azoic Yellow 1
460 C137100 Azoic Red 16
461
462
463
464
465
466
467
468
469
470
** Base Azoic
Dlazolc 34
Sale Azoic
Diazoic 34
CI37105 Sale Azoic
Dlazolc 12
Base Azoic
Diazoic 12
CI37107 Azoic Coupling 107
CI37110 Base Azoic
Diazoic 8
» Sale Azoic
Diazoic S
C137120 Salt Azoic
Diazoic 10
" Base Azoic
Diazoic 10
" Azoic Broun 10
471
Azoic Red 2
-------
B-%
Sources of
Compound
'
'
--
Proceas
No.
4
4
4
.' 4
4
4
4
4
4
4
4
4
4 '
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Dlazotizaclon
Coupling
Dlnzoclzaclon
Coupling
Dlazocizaclon
Coupling
Dlnzoeization
Coupling
Diazoclzacion
Coupling
Diazotizacion
Coupling
Diazocizacloa
Coupling
Diazocizatlon
Coupling
Dlazocizacion
Coupling
Diazotizacion
Coupling
Diazotizacion
Coupling
Dlazocizacion
Coupling
Dlazocizacion
Coupling
"Dlazocizaclon
Coupling
Diazotizacion
Coupling
Dlazocization
Coupling
DlaocizaClon
Coupling
Dlazocizaclon
Coupling
Dlazocizacion
Coupling
Dlazocizacion
Coupling
DlazocizaCion
Coupling
Dlazocizacion
Coupling
Diazocizatlon
Coupling
Dia-otizatlon
Coupling
DlazoclzaClon
Coupling
Dlazotizaclon
Coupling
Diazotlzation
Coupling
Diazotlzation
Coupling
Associated Uaaco
Wni'tt1:! Trt-ntmcnt
Wa tor;
salts
W;iter:
salts
Vatcr;
salts
Water:
sales
Water:
sales
Vater:
salts
Vater;
salts
Vacer;
sales
Vaeer:
sales
Vacer:
sales
Vacer:
sales
Vacer:
sales
Vacer:
sales
Vater:
salts
Vater:
sales
Vacer:
sales
VaCer:
salts
Vacer:
salts
Vater:
salts
VaCer:
salts
Vater:
sales
Vater:
sales
Wacer:
salts
Vater:
sales
V.iter;
sales
Vnter:
nalca
Water:
salts
Water:
salts
inorganic
inorganic
inorganic
Inorganic
inorganic
inorganic
inorganic
Inorganic
Inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
Inorganic
Inorganic -
inorganic
inorganic
inorganic
inorg-inlc
Total
ProOiict Ion
37.3 (82)-
1971
97.1 (214)-
1971
26.3 (W-
1973
-
137 (302)-
1973
77. J (170)-
1973
~
1973
45.0 (99)-
1971
15.5 (34)-
1973
2)330.
2)330.
2)330,
2)330.
_
2)330.
2)330.
__ __
~ -
.
"
""
Ill
HI
106
1143
1143
1143
-------
B-97
TAHLE E-3. (Continued)
Item
So.
Compound
Name and
Formula
Chen. Abtttr.
Registry Nw.
(WIN)
Orni
Lu>(
Toxlclty. Toxic Hnznrd R:ifln^
ToxlcoloKv
C.rM^W
472
Azoic Brown 7 '
473
Azoic Yellow 2
474
475
476
477
478
479
480
481
482
483
484
485
CI37125 Base Azoic
Dlazolc 5
Salt Azoic
Dlazolc 5
CI37130 Base Azoic
Dlazoic 13
" Sale Azoic
Dlazolc 13
C137135 Salt Azoic
Diazoic 1
CI37150 Azoic Red 12
Salt Azoic
Diazoic 42
CI37151 Salt Azoic
Dlazolc 14
" Salt Azoic
Diazoic 23
< Base Azoic
Dlazoic 14
i> Base- Azoic
Dlazolc 28
CI37155 Azoic Dlazoli
486 » Azoic Blue 7
487 CI37155 Azoic Violet 1
488 " Salt Azoic
Dlazoic 41
489 CI37175 Salt Azoic
Diazoic 20
490 Azoic Blue 6
491
Azoic Creen 1
492
493
494
495
496
497
498
499
500
CI371S5 Azoic Dlazolc 0
006232571*
Disperse Black 2 006232571
CI37210 Base Azoic
Dlazolc 4
C137235 Base Azoic
Dlazoic 43
I Salt Azoic
Diazoic 48
n Disperse Black 6
CI37255 Salt Azote
Dlazolc 35
CI37275 Salt Azoic
Diazoic 36
C137505 Azoic Coupling 2
00119904*
"U* 10S BZ
1920 orl-rac
TDLo 13gm/ki!/
52WI TFX:!4ED
orl-rat
-------
E-9.S
Sources of
.Compc-unJ
.
'
Process
No.
4
4
4
. 4 .
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Process
Diazocizacion
Coupling
Dlazocizacion
Coupling
Dlazocizacion
Coupling
Dlazoclzaclon
Coupling
Diazoeizaclon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Diazotlzaclon
Coupling
Diazoeizaeioc
Coupling
Diazocizacion
Coupling
Diazoeizaclon
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
Diazoeizaclon
Coupling
Diazocizacion
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
Diazocizacion
Coupling
-
Diazocizacion
Coupling
Diazocizacion
Coupling
Dlazocizacion
Coupling
-
Diazocizacion
Coupling
Diazoclzaclun
Coupling
Dlazocizacion
Coupling
Aasoclntcd Vnscc Total
Wastes Treacrent Production
Vacer:
sales
Vjcer;
salts
Vacer;
sales
Ha ear:
sales
Vacer:
sales
Vacer;
sales
Vacer:
sales
Vacer:
sales
Vaeer:
sales
Vaeer:
sales
sales
Vacer:
sales
Vaeer:
sales
7ater;
sales
Vacer:
salts
Vaeejr:
sales
Vacer:
sales
Vacer:
sales
Vaeer:
sales
Vaeer:
sales
Vacer:
sales
Vaeor:
sales
Vacer;
sales
Vacer;
sales
Uacer:
sales
v/iter:
sales
V.iter:
Bales
inorganic
inorganic 9.1 (20)-
1973
inorganic
Inorganic ia7i^36^~
inorganic
inorganic ~ 166 (365)-
1973
Inorganic los «38)-
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic
inorganic <
inorganic
inorganic
inorganic
inorganic ~
inorganic
inorganic
..
inorganic
Inorganic
inorganic
inorganic
Inorganic
inorganic --
Uses References
v
.
__
~
~
-------
: 11-3.
Item
So.
Cenpound
Name anJ
Forr.nila
Chen. Abscr.
Registry Ho. Oral Toxlclty, Toxic i!;iz:ird R.'ittnv-.
(WIN ) *-°5Q' l°.
-------
B-100
Sources of
Compound
'
.
Process
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
Pracoss
Dlazotlz.iclon
Coupling
Dlazoeizaeloa
Coupling
Dlazoeizaeloa
Coupling '
Diazoeizacion
Coupling
Diazocizaclon
Coupling
Diazoeizacion
Coupling
Diazoeizacion
Coupling
Slazoelzacloo
Coupling
Dlazoclzaclon
Coupling
Diazocizacioa
Coupling
Diazoeizacion
Coupling
Diazocizaclon
Coupling
Diazoeizacion
Coupling
Diazoeizacion
Coupling
Dlazoeizaeloa
Coupling
Dlazoelzatioa
Coupling
Diazottzation
Coupling
Diazocizacioa
Coupling
Diazocizacioa
Coupling
Diazoeizacion
Coupling
Diazocizacioa
Coupling
Diazcclzacion
Coupling
Dlazoclzaclon
Coupling
Diazocizacioa
Coupling
Diazoeizacion
Coupling
Diazocizaclon
Coupling
Dlazocizacion
Coupling
Diazoeizacion
Coupling
Diaz&Cizaclon
Cuupl Ing
Atf.sactatud Waste Total
Wn»ti-s Tr.'.Ttnont Projection t'-,'s 8><:'cr<.-r.Ci<*
Vater:
s.itra
W.itcr:
s.ilts
Vater:
sales
Water:
sales
Vater:
sales
Vacer:
sales
Vacer;
sales
sales
Vacer:
sales
Vater;
sales
Vaeer:
sales
Vaeer;
sales
Vaeer;
sales
Vaeer:
. sales
Wacer:
sales
Waeer:
sales
Wacer:
salts
Wacer:
salts
Vacer:
. sales
Vater;
salts
Vacer:
sales
Vater:
sales
Vaeer:
sales
Water:
sales
Water:
salts
W.i ec r:
salts
Water;
salts
W.i tor:
salts
w.it_cr:
ttalta
inorganic «
inorganic
inorganic
inorganic
inorganic
inorganic
Inorganic
inorganic 77.3 (170)-
1973
Inorganic
Inorganic 43. 2 '(95)-
1973
inorganic
Inorganic
inorganic
inorganic
inorganic
inorganic
inorganic 9.1 (20)
1973
inorganic
Inorganic
Inorganic
inorganic 137 O02'>-
1973
inorganic 37.3 (821-
1973
tnorganic
inorganic
tnorganic . .
Inorganic
inorganic
inorg.ir.tc
'
--
.
.
~
--
-------
B-101
TAU1J-: B-3. (Continued)
Item
No.
Compound
Numt! nml
Formula
dicta. At'utr*
Registry No.
(WLM)
Ornl
LU5(
Toxlcity,
A, Riv'./kc,
Toxic
ACIIH
llnznrJ Bntlnit
Clironlu
Toxicolo\:v
TLV .
Corel
IK'1
530 " Azoic Crcen 1
531 CI37595 Azoic Coupling 13
532 CI37600 Azoic CoupUug 15
533 " Azoic Btovin 3
534 " Azoic Brovra 7
535 CI37605 Azoic Coupling 16
536 CI37S10 Azoic Coupling 5
537 " Azoic Yellow 3
538 " Azoic Yellow 2
539 Azoic Yellow 1
540 C137615 Azoic Coupling 35
541 CI40000 Direct Yellow 11 001325377
542 C140001 Direct Yellow 6 001325338
543 CI40002 Direct Orange 15
544 CI40003 Direct Orange 15
545 CI40045 Direct Yellow 21
546 CI40210 Direct Orange 61
547 C140215 Direct Orange 39 001325548
548 " Direct Orange 34 301325548
549 CI40220 Direct Orange 34
550 CI40260 Direct Orange 37
551 CI40265 Direct Orange 37
552 CI40290 Direct Red 111
-------
B-iOi
Suurcrs of Process
CnwpeunJ NP.
4
4
4
4
4
4
4
. *
« «. A
4
4
5
5
i
5
5
5
5
~ 5
5
5
- - 5
*
~ s
rT,c,«
Diazotization
Coupling
Diazotization
. Coupling
Dlazutizatlon
Coupl lug
Diazotization
Coupling
Diazotizatloa
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Condensation
Precipitation
Filtration
Condensation .
Precloitatlon
Reduction
Filtration
11
Condensation
Precipitation
Filtration
Condensation
Precipitation
Filtration
. _ .
Condensation
Precipitation
Filtration
Associated Wuntu
Wnnto.1 Tiviitrccnc
Water: Inorganic
salts
Water: inorganic
salts
Water: Inorganic
salts
Water: Inorganic
salts
Water: inorganic
salts
Water: Inorganic
salts
Uater! inorganic -
salts
Uater: inorganic
salts
Water: Inorganic --
salts
Water: Inorganic
salts
Water; Inorganic
salts
Water: brines
containing small
amounts of organic
materials
Water: brines
containing small
acounts of organic
materials
Water: brines
containing small
anounts of organic
materials
Water: brines
containing small
aoounts of organic
materials
Water: brines
containing snail
aoounts of organic
materials
Water: brines
containing small
amounts of organic
materials
Water: brines
containing small
amounts of organic
materials
_
Water: brines
containing gmall
amounts of organic
rvtterials
Total
Production Us*-s
'
.
9.1 (20)-
1973
-.
1.220 (2,685)-
1973
265 (583)
1973 ~
57.3 (342)-
1973
f
57.3 (126)-
1973
46.8 (103)-
1973
N
11.8 (26)-
1973
"
R,-f,.renceS
~
r
*
-------
Compound
Hem Name mul
No. F^rrailn
Choc,. Abatr.
KcgUtrv Ko.
(VI.N)
TABU:
Or:il Toxlclty.
LO^p, KH'./^S
B-103
B-3. (Cout tmicJ)
Toxic H.iz:irrt R.itlny
Actitt' Chronic ToxlcoloKV
Tl.V Cure I
553 C140300 Direct Yellou 106
554 CI40600 Fluorescent
Brlghtcner 30
002t06931
555 CU0621 Fluorescent
Brightcner 9
000133664
556 CI40622 Fluorescent
Brlghtcner 28
004404437
557 CI40630 Fluorescent
Brightener 1
015339396
558 a40645 Fluorescent
Brightener 46
006il6633
559 CI41000 Basic Yellou 2 002465272 150 orl-cat
(1S1SR D2YUM
4CH)
TDLo:43 go/kg/
87WC, TFX:CAR
orl-rat
560 » . Solvent Yellou 34 000492808
561 C141001 Baste Yellow 37 " 006358367
562 CI42000 3aslc Creed 4
000559G42 LDLo:75 og/kg
(L6Y DYJ orl-rbt
AUYRSR DN1&1&
DUK 40 &2S/23)
TDLo:29 gm/kg/
'52WC, TFX:CAR
orl-oua
563
564
565
PIA Pigoent '
Green 4
PMA Plgo«nt
Green 4
566 CI42025 Pigaent Basic
Blue 2
000569642*
000569642*
Solvent.Green 1 000569642*
003521060*
567 " PTA Pigccnt
Blue 9
568 " PMA Pigrent
Blue 9
569 " Basic Elue 2
570 Basic Blue 1
571 CI42040 Soslc Green 1
003521060*
003521060*
003521060*
003521060
000633034
U6Y DYJ
AUYP.1R DX2S2&
DUK 242 iWST
0 425/34
LDI.o:25 ing/kg
orl-oiua
572
PTA PIRT.cnt
Crc.cn 1
00061303'.'
-------
H-104
Sources of
Compound
Proci.-si
So.
Prp.i-s*
Vault-
Total
koforcncfi
6.IS
6,13
6.18
6
6
6
6
6,18
6,18
6.18
6,13
Condensation
Oxid.it ion
Reduction
Condensation
Filtration
Reduction
Condensation
Reduction
Condensation,
Reduction
Condensation
Reduction
Condensation
Oxidation
Filtration
Condensation
Filtration
Precipitation
Condensation
Oxidation
Crystallization
Filtration
Condensation
Oxidation
Crystallization
Precipitation
Filtration
Water: brines
containing small
amounts of organic
nateriula
Wnter; brines
containing snail
amounts of organic
materials
Water; brines
containing snail
amounts of organic
materials
Water; brines
containing scall
amounts of organic
materials
Water: brines
containing s=all
anuunts of organic
materials
Water: brines
containing saall
amounts of organic
materials
Water; brines
contaminated with
small amounts of
organic materials,
residual arounts of
metal ions and
lead sulfate
Water: brines
contaminated vita
small 3ico--Tits of
organic cacerials
Also, lead sulfate
is precipitated
as a solid waste
336 (7391-
mi
Water: brines
coataainated with
small amounts of
organic eaterials,
residual amounts of
metal iona and
lead sulfate
523 fl.1511
197T
2)330, 110
312 (636)-
1973
2)330.110
2)330, 77
2)330.77
2)330.77
2)330,77
6.18
6.13
Condensation
Crystallization
Oxidation
Precipitation
Filtration
Wacer: brines
co.itamtnatcd with
small aian:mt3 of
organic n-itcrials,
residual amounts of
metal Ion4 and
lead sulfate
38.2 C84)-
2)75, 330
6.1.1
2)75.330
-------
11-105
TAI!l.v: B-3. (Continued)
Item
Xo.
573
S74
S75
376
577
Compound
N.131U ond
Formula
" PMV Pignent
Crecn 1
" PTA Pigoenc
Crcen 2
" FMA Pignent
Crcen 2
CI42045 Ac 14 Blue- 1
CI42053 FDSC Green 3
Chen. Abatr.
Registry tio. Or^il Toxlcttv. Tuxlc ll.imrd Kntliu:
(WIN) . . L'%50> "S/kiS Acut,- Cliroulr Toxicology
OOObJ3034*
00061.1014* _
000633034* _ ._
000129179 -- LD5Q:1200 mg/kg
ivn-miis
002353459 ~
(WSOiK DIN24R D-
2v*a DQ BSWO
&-S.\- 2)
TI.V Cjirclnot^cn^^^
.
--
1T>Lo:6500 ng/Ug/
33WI. TFX:NEO
acu-rac
TDLo:5925 og/kg/
48WI TFX:CAS.
ecu-rat
573 CI420SO Acid Blue 7
003436304
579 CI42085 Acid Green 3
0046307S3
(WSO&R D1N26R
D2V*R S-NA-)
TDLo:600 rng/kg/
43'JC, IFX-.CAR
oil-rat
580 CI42090 Acid Blue 9
002650182
(L6Y DYJ ALTR
BSUOR DN2&1R
CSWQ&Ji DUK2S1R
CSWQ SZH iZK
&37/17)
TDLo:17
2VI, IFX-.CAR
Bcu-rat
531
Lake Pigment
Blue 24
002650132*
582 " FDiC Blue 1
583 CI42095 Acid Green 5
002650182
005141203
(WSOSR DW2iR
D-2Y*R DSHO
4-SA- 2)
TDLo:1290 gm/kg/
86WC, TFXiCAR
otl-rat
584, CI42100 Acid Green 9
004857312
585 CI42140 Basic Blue 5
003343826
-------
R-lOf.
^Sources of
w
^
-
r-
__
«
.__
_
_
Process
No.
6,18
6.18
6.18
6,13
6
6
6
6.18
6
6
6
6
6,18
Process
n
-
M
Condensation
Crystallisation
Oxidation
Filtration
Precipitation
Condensation
Crystallization
Precipitation
Oxidation
Filtration
Sulfonatlon
Condensation
Crystallization
Oxidation
Filtration ^
Condensation
Crystallization
Oxidation
Filtration
Condensation
Crystallization
Oxidation
Filtration
Condensation
Crystallization
Oxidation
Filtration
Condensation
Precipitation
Oxidation
Filtration
Sulfonatlon
Condensation
Crystallization
Oxidation
Filtration
Condensation
Crystallization
Oxidation
Filtration
Precipitation
Associated Waste Total
Wnstos Treatment Production Uses References
' . 2.7 (5)- _ _
1973
M _ _ _
30.5 (67)- _ _
1973
W.irer: brines 2)330, 421
contaminated with
sull amounts of
organic materials.
residual amounts of
metal Ions and
lead sulfacc
Water: brines
contaminated with
snail amounts of
organic materials.
and lead sulfate
Is precipitated
as a solid waste
Water: brines
contaminated with
scull amounts of
organic materials
and lead sulfate
is precipitated
as a solid waste
Water: brines 93.6 (2061- 2)330, 80
contaminated with 1973
scall amounts of
organic materials
and lead sulface
Is precipitated
as a solid waste
Water: brines - 971 (2.136)- _ 2)330, 80
contaminated with 1973
scall amounts of
organic materials
and lead sulfate
is precipitated
as a solid waste
Water: brines 21330, 80
contaminated with
scall amounts of
organic materials
and lead sulfate
Is precipitated
as a solid waste
" 3j_2 (183). 2)330, 80
1973
Water: brines 2)330. 80
contaminated with
scall aaounts of
organic materials
and lead sulfate
is precipitated as
a solid waste
Water: brines
contaminated with
scall amounts of
organic materials
and lead sulfate
is precipitated
as a solid waste
Wa_ter: brines 7.3 OM-
contaminated with 1973
sivill amounts of
organic miturials
residual amounts of
m':t-'il ions and
lend sulfate
-------
B-10/
TABLE l<-3. (CoilUiluuJ)
Compound
Item N.ime ond
So. Formula .
Chaos. Abatr.
Registry No.
(I.-LN).
Or.il Toxlcity, Tnxfc Hnsnnl Riitt
Li'^Q. niji/^S Acvn>! CliroiUc
Toxtcolot-.v
586 CI42170 Acid Green 22
005S63514
587 C145170 PTA Pig=enc 001326030*
Violet 1
533 CU2500 Saslc Red 9
000548618
539 CI42510 Basic Violet 14 000632995
590
PMA
Violet 9
591 " Solvent Red 41
592 CI4ZS20 Basic Violet 2
593 CI42535 Basic Violet 1
000632995*
003243939
003243917
OOS004873
594
595
PTA Pigzent
Violet 3
PMA Pigment
Violet 3
008004873*
008004873*
596 Solvent Violet 8 003004873*
597 CI42536 Basic Violet 13
-------
n-ioa
Sources of
Compound
Process*
No.
Process
Associated
Waste
Tot.il
Production
Uses
References
11.13
Condensation
Crystallization
Oxidation
Filtration
Precipitation
Filtration
Condensation
Water; brines
contaminated with
scull amounts of
organic caterlals
and lead sulfnte
Is precipitated
as a solid waste
S«e C145170
52.3 (115)-
1973
Oxidation
Filtration
Oxidation
Filtration
Air: possibly
significant and
hazardous amounts of
toxic arylamincs
Water; brines
contaminated
with varying
aoounts of organic
substances
Solids; sludges
containing large
aoounts of cetal
Ion3
Air: possibly
significant and
hazardous amounts of
toxic arylamines
Water; brines
contaminated
vlth varying
amounts of organic
substances
Solids: sludges
containing large
anounts of cetal
ions
Oxidation
Filtration
Benzylatlon
Oxidation
Filtration
Benzylatlon
Air: possibly
significant and
hazardous amounts of
toxic arylamines
Water: brines
contaminated
with varying
amounts of organic
substances
Solids: sludges
'containing large
aaounts of cvetal
ions
Air; possibly
significant and
hazardous amounts
of toxic arylaalnea
Water: brines
contaminated
vlth varying
amounts of organic
substances
containing large
anounts of necal
ions
555 (1,221)-
1973
18.2 (40)-
1973
191 (421)-
1973
-------
P.-109 .
TAIlIK l:-3. (Condiuifvl)
Item
No.
593
Compound
Name and
IVnmila
CI42555 Basic Violet 3
Chum. Abstr.
Registry Ho.
O-'LN)
000548629
(INUR D-
3Y* iC)
Or;il Toxlclly.
L'.'50. BIS 7 1. f.
1000 orl-rat
Toxtc Hnrnrd R;Uln'.'.
Acute Chrotitc Toxtcolo^v
LDLo:15 mg/kg
Ip r- rat
TLV Ore
--
599 " Solveac Violet 9 00054629*
600 CU2561 AciJ Blue 34 006^60055
1000 orl-rac
601 CI4259S Sa-ilc Blue 7
002390605
602
603
604
605
" Solveac Blue 5
PTA Pigcent
Blue 1
" PMA Pigaent
Blue 1
.C142600 PTA Pigceat
001325366
001325377*
001325877*
002390505*
Blue 14
606
?XA Pigseac
Blue 14
607 Basic Violet 4
608 CI42640 Acid Violet 49
002390592*
002390592
001694093
TDLo:9400 mg/kg/
2YI, TFX:NEO
scu-rac
609 FD4C Violet 1 001694093
610 CI42645 Acid Blue 15 005363467
611 CI42650 Acid Violet 17 004129344
61Z CI42655 Acid Blue 90
006104581
613 CI42660 Acid Blue 83 006104592
614 CI42735 Acid Blue 104 006305302
615 » Lake Acid 006^05302*
Blue 104
-------
B-tIO
Sources ot
Compound
Process
Nc.
Prccoas
Associated
Ujstes
Waste
Total
Product ion
Uses
References
8.1J
Condensation
Filtration
Precipitation
JUr_: snwll amounts
ot phosgene
Water: IcaJ sulfate
precipitate nnd
brine which cor.cains
lead and small
amounts of organic
caterlala and
residual aaoimcs of
cecal Ions
2)330, 73
8.13
3
2)330. 73
6,13
Condensation
Filtration
Sulfon-ition
Condensation
CrystallizaClon
Oxidation
Filtration
Precipitation
Atr; small amovnts
of phosgene
Water: lead sulfate
precipitate and
brine vhich contains
lead and small
aaounts of organic
materials
Water: brines
contaminated with
snail aaounts cf
organic caterials.
residual aeounts of
cetal ions and
lead sulfate
78.2 f!72>-
1971
6.18
6.18
6,18
8,13
Condensation
Filtration
Precipitation
Air: small amounts
oc phosgene
Water: lead sulfate
precipitate and
brine which contains
lead and snail
aaounts of organic
materials and
residual amounts of
oe cal loos
45.9 (101)-
1973
8,18
8.18
18
18
Precipitation
Filtration
Water: brines
cay also contain
residual aaounts of
oetal ions
26.4 (58)-
1973
2)330, 77
77
18
Precipitation
Filtration
Condensation
Oxidation
Precipitation
Filcracion
Sulfor.atlon
Water: brines
cay also contain
residual amounts of
cetal ions
Water: brines
contaminated with
small amounts of
organic materials
end lead sulfa-.c
is precipitate-!
as a solid waste
13.2 (29)-
1973
-------
Item
So.
Compound
Nsine and
For nail a
Chcc. Abacr.
Registry No.
B-lll
TAHLE U-3. (Continued)
Oral Toxtclty, Toxic Hasan! Knftm-.
U)so. ma/is Ac,,,.. C|,ro,a,.
ToxlcoloHv
TLV
Carcincp.
616 CI4:750 Plgoent Blue 19
617 CU2760 Solvent Blue 23 002152549
618 CU2775 Solvent Blue 3
619 C142780 Acid Blue 93 028933564
620 CI43320 Mordant Blue 3 . 003564189
621 CI43830 Mordant Blue 1 001795925
622 CI44025 Acid Green 16 001325446
623 CI44040 Saslc Blue 11 002185866
624
625
626
Solvent Blue 6
PTA Plgaent
Slue 10
PMA Pi&neot
Blua 10
627 C144045 PTA
Bluo 2
006736841
002185866*
002185866*
002', 30565*
-------
P-112
Sources of
Cotnrvund
Process
No.
Process
Associated
Wastes
Wnate
Tri'.ntmcnt
Toinl
Production
Usus
18
7
Precipitation
Filtration
Condcnsa tlon
Filtration
Oxidation
Condensation
Filtration
Oxidation
Water: brines
may also contain
residual amounts
of mctnl ions
Air: possibly
significant and
hazardous amounts of
toxic arylaaines
Water: brines
contaminated
vith varying
amounts of organic
substances
Solids: kludges
containing large
amounts of octal
ions
Air: possibly
significant and
hazardous amounts of
toxic arylaaines
Water: brines
contaminated
with varying
amounts of organic
substances
Solids; sludges '
containing large
amounts of metal
ions
Condensation
Oxidation
Filtration
Air: noxious gas
emissions from
use of nitrogen
oxides
Water: brines
containing small
aicounts of organic-
materials
10.13
10.18
10.18
Condensation
Oxidation
Filtration
Condensation
Oxidation
Condensation
Oxidation
Nltrosatlon
Hydrolysis
Precipitation
Filtration
Air: noxious gas
emissions from
use of nitrogen
oxides
Water: brines
containing small
aoounts of organic
materials
Ain small amounts
of phosgene
Water: lead sulfate
precipitate and
brine which contains
lead and scall
amounts of organic
materials
Air; nitrogen
oxides and
formaldehyde
Water: brines
containing heavy
metal ions
Sollda; distillation
residues and
precipitated lead
sulfate
37.7 (83)-
1973
10.18
10.18
Condcn.nat ion
Oxidation
Nltrosatlon
Hydrolyslti
TreeIpltat Ion
Filtration
A_^r_: nitrogen
oxiduM and
forinnlclchyde
V;i_£rr: brines
contaltttng hu.lvy
n»:t.nl lon.'i
Sol.lilii: 'IlKtUlatlan
rf»l»tiuT, nntl
-------
11-113
TAUI£ 11-3. (Continued}
I ten
Mo. _
628
629
630
631 .
Compound
Karoo And
F.
-------
B-114
Sources of
ComtXMim!
Process
"o.
Process
Astioclnlud
U.-istos
Una to
Total
10.18
11
10.18
10,18
Condensation
Oxidation
Condensation
Cycllsation
Oxidation
Air: small amounts
of phosgene
Water: lead sulfate
precipitate and
brine which contains
lead and small
acouats of organic
materials
Water: brines
contaminated with
scall amounts of
organic chemicals
Solid: sludge o£
iron oxide
13.2 (29)-
1973
2)22. Splmnc
11.18
11.18
11.18
11,18
11,18
11.18
11,18
11
11
12.18
Precipitation
Filtration
Condensation
Precipitation
Filtration
Condensation
Esterificatlon
Condensation
Condensation
Condensation
Condensation
Precipitation
Filtration
Halogenation
Water: brines
contaminated with
saall amounts of
organic chemicals
and residual amounts
of metal Ions
Solid! sludge of
Iron oxide
Water: brines
contaminated vith
saall anounts of
organic chemicals
aad residual a^ouncs
of cetal ions
Solid; sludge of
iron oxide
Water: brines
contaminated vith
small amounts of
organic chemicals
Solid: sludge of
iron oxide
Water: brines
contaminated vith
small aoounts of
organic chemicals
Solid: sludge of
iron oxide
U'Ater; hydro^n
halidu and s-tall
amnunts of hl;;hly
colored products and
residual amounts of
octal ions
42.7 (94)-
1973
294 (646)-
1973
(115)-
1973
143 (315)-
1973
2)330. 557
2)330, 557
2)330. 557
-------
Item
No.
643
649
650
651
652
Compound
N.*tn« and
Fortsula
C1453SO D&C Red 22
Acid Red 87
" Pigaenc Red 90
D&C Red 21
CI45410 Oic Bed 27
B-115
TAHIi: B-3. (Coiiltiiurd)
Choc. Ahstr.
Registry No. Oral To>:i^lty. Toxic Hnzarv! K:ili
-------
B-116
Sources of Process
Compound No. Process
12,18 Precipitation
Filtration
Halogenatlon
Associated Waste Total
Wastes Ttv:tr i-nt Production
Wrtter: hydrogen
hallde and small
amounts of lilt*,hly
colored products and
residual amounts of
metal Ions
Usi'S References
2)330. 557
12.18
12.18
12.18
12. IS
Precipitation
Filtration
Balogcnation
Water; hydrogen
hallde and snail
amounts of highly
colored products and
residual amounts of
netal Ions
720 fl.«3V
1973
12.18
12.18
12,18
13
14.
14
14,15.
18
14.15
18
14,15
Precipitation
Filtration
HalogenatIon
Precipitation
Filtration
Balogenation
Oxidation
Condeasatlon
Nitration
Reduction
Cyclization
Cyclizatlqn
Balogination
Amlnaelon
Condensation t
Condensation
Sulfeaation
Precipitation
Filtration
Condensation
Sulfonation
Water: hydrogen
halide and small
amounts of highly
colored products and
residual amounts of
metal ions
Water:
halide and small
amounts of highly
colored products and
residual acrouncs of
metal ions
Air: nitrogen
oxides and
formaldehyde
Water: brines
containing heavy
metal ions
Solid: distillation
residues and
precipitated lead
sulfate
Hater: brines
containing saall
amounts of
organic chemicals
Solid: acidic
wastes
Water: possibly
brines contam-
inated with
szall amounts
of organic
materials
Water: dilute
sulfuric acid
and brine
solutions
contaminated
with small
aoounts of
organic chcnlcals
and residual amounts
of metal Ions
Water; dilute
sulfuric acid
and brine
solution*
contanln-itcd
..with nm.ilI
amounts of
organic chccilcaln
and residual ntmunts
of mctnl Itmn
155 (340)-
1973 -.
2)330, 558
6ns
-------
B-117
TAIIU: u-3. (co
It«a
KC-.
Compound
(ittmo naj
Formulii
Client.
Registry No. Ornl TyxUlty, Toxtc llnr.nnl Rtittnv;
(WLN) . _ LP50' "''' ^ _ Acut>- Clu-onti:
Toxicology
Tl.V
CarctnoBcJ
663 0147023
Yellow 64
012223368
664 CI47035 Direct
Yellow 5
665 CI48000 Disperse 004361346
Yellow 31
666 CI43013 Basic Violet 16
667 CI48013 Basic Red 13 003643360
668 C14S020 Basic Violet 7 006441323
669 CI48035 Basic Orange 21 003056937
670 CI48040 Basic Orange 22 004657005
671 CI43055 Basic Yellow 11 004203304
672 CI43070 Basic Red 12 006320145
673 CI48100 Basic Yellow 23
674 CI49000 Direct 00806.'.606
Yellow 59
-------
B-ua
Sourcoi of
- Compound
Process
Process
Associated
Wnsti-s
Wnste
Total
Production
UHOJ
References
14,15
Condensation
Condensation
Sulfonatlon
Condensation
Filtration
16
16
16
16
16
16
16
17
Condensation
Condensation
Condensation
Condensation
Condensation
Condensation
Condensation
Condensation
Kethylatlon
Sulfonation
Dehydrogcnation
Water; possibly
brines contami-
nated with
email amounts
of organic
materials
Water: dilute
sulfurlc acid
and brine
solutions
contaminated
with small
amounts of
organic chemicals
Air: noxious gas
emissions from
use of nitrogen
oxides
Water; brines
containing soall
amounts of organic
materials
Water: acidic
brines containing
small amounts
of organic
chemicals
Water: acidic
brines containing
small amounts
of organic
cheoicals
Water: acidic
brines containing
small amounts
of organic
chemicals
Water: acidic .
brines containing
small amounts
of organic
cheaicals
Water: acidic
brines containing
small amounts
of organic
chemicals
Water: acidic
'brines containing
small amounts
of organic
chemicals
Water: acidic
brines containing
small amounts of
organic
chemicals
Water: acidic
brines containing
small amounts of
organic
chemicals
Air: possibly
hydrogen sulflde
Water: dilute
sulCurlc acid
and ammoniacal
brine contaminated
with small amounts
of organic material
65.5 (144)-
1973
216 (476)-
1973
13.6 (30)-
1973
427 (939)-
1973
755 fl.661)-
1973
-------
Itvm
Compound
Naino and
Fomntln
B-M'I
TABI>: 11-3. (t\M
Cher:. i\bt>cr.
Registry No. Ornl Toxl^tty, Toxic Hnrttnl R;tcin.q
Lll-ip. "^'kS Aon.- au-onic
TLV
Corctno]
675 CI49005 Basic Yellow 1 002W0547
676
677
PMA Plga
Creen 2
00:390547
PTA Plg=ent 002390547
Green 2
678 CI49013 Direct Yellow 7 015724693
679 CI50204 Basic 0
6SO CI50240 Basic Red 2 000477736
681 CI50400 Solvent Blue 7 OOS004936
682 C150405 Acid Blue 20
683 CI50415 Solvent Black 5 012227804*
684 " Solvent Black 7 012227804
685 CI50420 Acid Black 2 012227815
685 CI51004 Basic Blue 4 002787919
-------
B-120
Source* of
Process
No.
Associated
Wastes
Waste
Tn-n input
Toul
Produ.'t Ion
17.18
17.18
Methyl.icion
Sulfon.it ion
Dchydrogcnaclon
Prcc Lpitution
Filtration
Air: possibly
liyJrogen .tulflde
Ujiti-r: .dilute
Huluirlc acid
and anuaonlacal
brine contaminated
vlth small amounts
o£ organic caterl.il
and residual amounts
of metal Ions
23.6 (63)-
1973 '
17.18
17
19
Methylation
Sulfonjtlon
DenydtogenatIon
Condensation
19
19
Oxidation
Precipitation
Fractional
Condensation
15.18
Sulfonation
Condensation
19
Condensation
19
15
Sulfonation
20
Nit ron,it Ion
Condensation
Air; possibly
hydrogen sulfide
Waier: dilute
sulfuric acid
and ammoniacal
brine contaminated
with small amounts
of organic material
Water: effluent
would contain
chloride, iron,
and chromium Ions,
as veil as
small amounts of
organic materials
Hater: effluent
would contain
chloride, iron,
and chromiuB Ions,
as well as
snail amounts of
organic materials
Water: effluent
would contain
chloride, iron,
and chromium ions,
as veil as
small amounts of
organic materials
Hater: dilute
sulfuric acid
and brine
solutions
contaminated
with small
amounts of
organic chemicals
and residual amounts
of metal ions
Water: effluent
would contain
chloride. Iron,
and chromium ions,
as well as
small amounts of
organic materials
Water: dilute
sulfuric acid
and brlno
solutions
contaminated
with small
amounts of
organic chemicals
W.vt£r: brine*
containing Hnnll
anounts of organic
nntcrInlH
-------
TAIILH n-3. (i\>ntlm:i:d)
Compound Chi*n. Ab«lr,
Item . Name nnd Ro^istvy No. Oral Toxlclty, ' Toxic M.iE.-ml Knttn^
No. Formula . O'LN) ^O- "t'/^B Aculi- i:lnvnli: Toxlcolonv TLV ; Cnrctno
687 " Basic Blue 3 002737919 .
683 CI51175 Basic Blue 6 000966621
6S9 CIS1300 Direct Blue 106 0065:7704
690 CI51319 Pigment 006353301
Violet 23
691 C151320 Direct Blue 103 001324539
692 CI52015 Basic Blue 9 000061734 LDLoUOO ng/kg
(T C666 BS Ivn-Dus
ISJ FNlil LD50:82 mg/kg
LNJil &G &12/28 Ivn-mus
693 C1S3000 Leuco Sulfur
Brown 1
694 CI53001 Solubilized Sulfur
Brown 1
695 C153010 Leuco Sulfur
Tellow 9
696 CIS3040 Leuco Sulfur
Yellow 1
697 CI53050 Sulfur Orange 1
698 CI53055 Sulfur Brown 10
699 " Leuco Sulfur
Broun 10
700 CI53056 Solubilized Sulfur
Brown 10
701 CI53090 Leuco Sulfur
Brown 26
702 .. Sulfur Brown 26
703 CI53120 Leuco Sulfur
Yellow 2
-------
li-U'3
Sources of
Compound
Process
Process
Associated
Unsta*
Waste
Trtrnrnu'n
Total
Production
Rofrrenc
20
20 Nltro.iatlon
Condensation
341 (751)-
1973
20
20
15
21
22
22
Condensation
Sulfonation
Condensation
CyclijJtion
Sulfonation
Oxidation
Cy dilation
Precipitation
Filtration
Baking
Filtration
Baking
Filtration
W.Tferl brine
containing soatl
amounts of
organic chemicals
Water: brine
containing snail
amounts of
oiganic chemicals
Water: brtne
containing snail
acpunts of
organic chemicals
Water: dilute
sulfurlc acid
and brine
solutions
contaminated
vith small
amounts of
organic chemicals
Vater: brine
containing >tav
An, Al, and
Cr ions.
Water: brines
containing inorganic
sulfur compounds and
small amounts of
organic chemicals
Water: brines
containing inorganic
sulfur compounds and
snail amounts of
organic chemicals
127 (280)-
1973
2)330. 872
22
22
22
22
Baking
Filtration
Baking
Filtration
Baking
Filtration
Vater: brines
containing Inorganic
sulfur compounds and
small amounts of
organic chemicals
Water: brines
containing inorganic
sulfur compounds and
scall amounts of
organic chemicals
Water: brines
containing inorganic
sulfur compounds and
scall arounts of
organic chemicals
22
22
22
Baking '
Filtration
Baking
Filtration
Water: brines
containing inorganic
sulfur compounds and
ssall amounts of
organic chemicals
W.iter; brines
containing inor^nnic
sulfur conipomtdr. and
small amounts of
organic chemicals
-------
TAIIU: B-3. (ContinuoJ)
Item
So.
Coapound
Nnne nnd
Chcm. Abfltr,
Rcglitry No.
(VLN)
Toxl
-------
Ii-124
Sources of
Compound
Process
Untiti*
Total
Produce ton
Rofcrt*nc**
Baking
Flic radon
Water: brluyM
containing Inorganic
sulfur compound*
and small amounts
of organic chemicals
22
22
Baking
Filtration
Water: brines
containing inorganic
sulfur compounds
and small amounts
of organic chemicals
22
22
22
Condensation
Condensation
Condensation
Water: brines
containing Inorganic
Sulfur compounds
and small amounts
of organic chemicals
Water: brines
containing Inorganic
sulfur compounds
aad small amounts
of organic chemicals
22 Condensation
Water: brines
containing inorganic
sulfur compounds
and small amounts
of organic chemicals
22 Condensation
22 Condensation
22
Water: brines
containing Inorganic
sulfur compounds
and small amounts
of organic chemicals
Water: brines
containing Inorganic
sulfur compounds
and small amounts
of organic chemicals
22 Condensation
Water: brines
containing inorganic
sulfur compounds
and small amounts
of organic chemicals
22
22
22
22
22
Condensation
Baking
Filtration
Baking
Filtration
Water: brines
containing inorganic
sulfur compounds
and small amounts
of organic chemicals
Water: brines
containing inorganic
sulfur compounds
and small atounts
of organic chemicals
Water: brines
containing inorganic
sulfur compounds
and diKill amounts
of organic chemicals
W.itcr: brings
contiiinin^ liiorj?..inlc
siilfur cnmpoiuttlft
find Htn.'lll n.iMituit'l
of orjvnilc rlu
-------
n-m
TAIIIJ; B-3. (Continued)
Itca
Coopound
Narje find
Clicm. Abstr.
Registry No.
Or:il Toxlclty, Toxic ISninnl K,irtnK
LD.,0. ninAi; Acuct- Cli route
Tos'.coloKv
. TI.V
72J " Lcuco Sulfur
Blue 7
724 CIS3A41 Solublltiod
SulCur Blue 7
0013J7577
725 CI53450 Leuco Sulfur 012:62269
Blue 13
726 CI53570 Leuco Sulfur
Green 3
727 CI53571 Leuco Sulfur
Creen 2
728 " Sulfur Creea 2
729 CI53630 Vat Blue 43
730 CI53680 Leuco Sulfur
Brown 20
731 CI53720 Sulfur Red 6
732 CI53721 Sulfur Srown 12
733 CI53830 Leuco Sulfur
Bed S
734 " Sulfur Red 5
735 CI5SOOO Mordant Red 11 000072430
736
Lake Ftgraent
Red 83
737 CI58005 Mordant Red 3
738 CIS8055 PTA Pigment
Blue 7
739
PKA Plgaent
Blue 7
740 C159040 Ext. DIG
Creen 1
000072480*
000130223
006358696
741 CI59100 Vac Yellow 4 000128665
-------
B-126
Sources of
Compound
Process
Ko.
Process
Auuoclntcd
V:i sees .
Tri-ntip.>-;it
Total
Product ton
Reference*
22
22 Condensation
22 Condensation
22
22
22
22
22
22
Condensation
Condensation
Condensation
Baking
Filtration
Condensation
Water: brines
concatninc: Inorganic
sulfur compounds
and small amounts of
organic chemicals
Water: brines
.containing Inorganic
sulfur compounds and
small amounts of
organic chemicals
Water; brines
containing Inorganic
sulfur compounds and
soall airounts of
organic chemicals
Water: brines
containing inorganic
sulfur compounds and
small amounts of
organic chemicals
Water: brines
containing inorganic
sulfur coc-pounds and
small amounts of
organic chemicals
Water: brines
containing inorganic
sulfur conpounds and
small amounts of
organic chemicals
Water; brines
containing inorganic
sulfur compounds and
small amounts of
organic chemicals
22
22
23
23
Condensation
Hydrolysis
Oxidation
Water; brines
containing inorganic
sulfur conpounds and
snail amounts of
organic chemicals
Water: brine containing
sodium sulfite and
ftmall amounts of
organic materials
30.9 (68)-
1973
24
26
Hydrolysis
Benzylation
Cycllzatlon
Condens.i tlon
Reduction
Water: effluent
containing sodium
sulfite
Water: brlnus
ulth excess alkali,
manganese ion,
or aluminum Ion and
org-inlc substances
Sullrt; oxide Bludge
44.6 (98)-
1973
-------
ll-U'7
TAHIK B-3. (CjiiLliiurd)
Item
No.
Compound
Nrtiao nnd
fcruai In
Choa. Ahttr.
Registry No. Or:il ToxUlcy, ToxU- lUrnrd S.iitns
**UM)' '"l'"'kt'. Acuto Clii.juU ToslcoloKv
TLV
Cnrclnotenl
742 CI59101 Solul>lll:ed Vat . 003564703
Yellou 4
743 CI5910S Vac Orange 1 001324114
744 CI59106 Solublllscd Vat 001324153
Orange 1
745 CI59300 Vac Orange 3 00437S614
746 « Plgmeoc Red 168 OO
747 CI59700 Vac Oraage 9 000123701
748 CI59705 Vac Orange 2 001324352
749 CI59710 Vat Orange 4 001324330
750 CI59800 Vac Blue 20 001324330
751 CI59815 Vac Blue 18 001324545
752 C159825 Vac Green 1 000123585
753 CI59826 Solublllzed Vat 002538843
Green 1
754 CI59350 Vat Green 9 006369659
755 Cl60000 Vac Violet 10 000123643
-------
D-128
Process
No.
Associated
Wnste
Total
Production
References
15
Sulfon.it ton
Water; dilute
Bult'urlc acid
and brine
solutions
contaminated with
small atwunts of
organic chemicals
Balogeaacion
SulfOD.it ion
12
12
25
12
12
26
12
26
15
26
27
Balogenation
Dimortization
Cycll:ation
Purification
Balogeaacion
Halogenacion
Alkali Fusion
Condensation
Seduction
Ralogenation
Reduction
Condensation
Alkali Fusion
Oxidation
Methjlatlon
Sulfotiatlon
Condensation
Reduction
Nitration
Alkali Fusion
Chlorinatlon
Water; hydrogen
hallde and srvjll
accunts of hip.hly
colored products
Water: dilute
sulfuric acid
and brine
solutions
contaminated with
saall aoounts
of organic
chemicals
Water: hydrogen
halide anil small
amounts of highly
colored products
Water: brine
containing small
aoounts of
organic chemicals
Water; hydrogen
hallde and small
aoounts of highly
colored products
Water; hydrogen
halide and snail
amounts of highly
colored products
Water; brines
with excess alkali,
manganese ion,
or aluminum ion and
organic substances
Solid: oxide sludge
Water: hydrogen
balide and snail
amounts of highly
colored products
Water: brines
with excess alkali,
manganese ion,
or aluminum ion and
organic substances
Solid: oxide sludge
Water: dilute
sulfuric acid
and brine
solutions
contaminated
with small
amounts of
organic chemicals
Water: brines
wltlt uxc«ss alkali,
cangnnese ion,
or aluminum ion and
organic substances
Solid: oxide sludge
Wjjt_c£: dilute
hydrochloric ncld
sodium sulfidu
and aang'lnou.1
sulfatc
592 (1.303)-
1973
129^83).
(458)-
1973
427 (939)-
1973
944 (2.077)-
1971
-------
C-129 ';.-.
TAIU£ B-3. (Com Im.cJ)
Compound Clion. Ahstr.
Item Narao nnd Registry No. Drill ToxUl'v, Toxfc ll:mirii Snitng
Xo. Formula CULN) LL).,0. ayi^r, Acuto Chronic ToxlroloKv TLV
756 CI60005 Vat Violet 9 0013J4170
757 CI60010 Vac Violet 1 001324556
758 » Pigment Violet 31 OOU24556
759 C160015 Vat Blue 26 004430551
760 CI60505 Solvent Red 111 000032382
761 " Disperse Red 9 000082382
762 CI60710 Disperse Red 15 000116358
763 CI60725 Disperse Blue 72
764 " " Solvent Violet 13 000031481
765 " .' DiC Violet 2 000031481
766 CI60730 Acid Violet 43 004430186
767 CI60755 Disperse Red 4 002379900
768 CI60756 Disperse Red 60 017418585
769 CI60767 Disperse Blue 27
770 CI61100 Disperse Violet 1 000128950
771 CI61102 Disperse Violet 23
772 CI61105 Disperse Violet 4 001220946
773 CI61115 Disperse Blue 9
774 C161125 Acid Blue 23 033140339
-------
Source* of
Compound
Priwcsa
No.
Ahaocintcd
Vatic
Trr;>trr.i-;it
Total
Product ton
Roferencos
12
12
12
27
28
Halogen.lt ton
Halogenation
Water; hydrogen
ballde anil :-.uiull
omounts of highly
colored provinces
Water: hydrogen
halide and small
amounts of highly
colored products
Oxidation Vatcr: dilute
Desulfurizatlon hydrochloric acid
Hethylation aodiua sulfido,
Chlorinatlon nanganous sulfate,
Sulflde Formation and brines
containing small
quantities of
organic compounds
Amlnolysis
Water: brines
containing small
amounts of organic
chemicals
130 (287)-
1973
23
23
15,23
Oxidation
Amlaolysis
Sulfoaation
Oxldatloa
Amlnolysis
Water; brine containing
sodium sulfice and
small amounts of
organic materials
Water: dilute sulfuric
acid and brine
solutions contaminated
with small amounts
of organic chemicals
and sodium sulfite
15,23
15.23
29
30
23
23
Hethylation
Condensation
Amlnolysis
Oxidation
Amlnolysis
Water; brines
containing saall
amounts of organic
chemicals
Water; brines
containing small
amounts of organic
chemicals and
possibly small
amounts of heavy
metal ions
Water; brines
containing small
amounts of organic
chemicals
Water: brines
containing small
accounts of organic
chemicals
930 (2,047)-
1973
«6.8 (103)-
1973
29
23
28
Methylation
Oxidation
Amino Lysis
Amlnolyuis
Water; brines
containing small
amounts of organic
chemicals
Water: brines
containing small
aimuntH of organic
chemicals
Water; brines
containing xmall
amoiintH of organic
chemicals
-------
H-m
TABU; 11-3. (Cj
Compound Chen. Abxtr.
Icon N.tao and Registry No. Orjil Toxlslty, Toxtc '.hiznnl Knclns
«,>. _ Formula _ 1WLN) _ U150- mM** _ ACHU- Clu-ontc _ ToxlcoloRy _ TIV
775 CI6U3S Acid Blue 127 ~ ~ ~
776 CI61200 Reactive Blue 19 002530781
777 " Solvent Blue 12
778 C161205 Reactive Blue 5 016323511
779 " Reactive Blue 4 013324204
780 CI61211 Reactive Blue 2 012236827
781 CI61500 Disperse Slue 14 002475447
782 CI61505 Disperse Blue 3 002475469
783 CI61525 Solvent Blue 11 000128358
784 CI61530 Acid Blue 27
785 CI61551 Solvent Blue 36 012226732
786 CI61552 Solvent Blue 59
787 CI61555 Solvent Blue 14 002645153
788 CI61565 Solvent Green 3 000123803
739 " DSC Green 6 000128803
790 CI61570 D4C Green 5 004403901
791 " Acid Green 25 004403901
792 CI61585 Acid Blue 80 004474242
-------
Sources of Process
Compound . No.
Process
AuuoctnCctl
. Unsti'S
What*
Tn-.itKvnt
Total
Product Ion
23 Aminolysts
28
Amlnolysis
Writer; brines
coutain Ins small
uaounts of organic
chemicals
W.iter: brines
containing small
amounts of organic
chemicals
28
28
Aalnolysis
Kjter; brines
containing small
arounts of organic
chemicals
28
23
28
28
28
15
28
28
28
15,28
Aminolysls
Oxidation
Aulnolysis
Oxidation
Aminolysis
Anlnolysls
Sulfonaclon
Amlnolysls
Oxidation
Aminolysis
Oxidation
Amlnolysls
Oxidation
Sulfonaclon
Oxidation
Amlnolysls
Vlater: brines
containing small
amounts of organic
chemicals
Water: brines
containing small
amounts of organic
chemicals
Hater; brines
containing small
amounts of organic
chemicals
Water: brines
containing small
amounts of organic
chemicals
Water; dilute
sulfuric acid
nad brine
solutions
contaminated
vith small aoounts
of organic
chemicals
Water: brines
containing small
amoves of organic
chemicals
Water; brines
containing small
amounts of organic
chemicals
Water: brines
containing small
amounts of organic
chemicals
Water: dilute
sulfuric acid
and brine
solutions
contaminated
with snail amounts
of organic
chemicals
619 (1.36D-
1973
67.7 (149)-
1973
93.6 (217)-
1973
15.28
15,28
Sulf (nation
Aminolyola
W.-itor: dilute
BulEuric acid
and brine nultitlonn
cont.-imtn.itcd with
small finout^ttt of
organic chutulcain
153 (336)-
1973
-------
B-133
TAP.I.K lt-3. (ContlmitMl)
Item
CotapouttJ
Nnao ond
Formula
Chen. Abstr.
Registry No.
(KIN)
Oral Toxlclty, Toxic llnsnrj RiUlm;
LU50- "8' k«' Acntj Clir.-nlc
Toxlcolof.y
T1.V
CarclneacJ
793 C161705 Solvent Violet 14
794 CI61710 Acid Violet 34 0064Q3535
795 CI6172S Vac Yellow 3
796 C161800 Acid Violet 34
797 CI62015 Dlspatse Red 11 002872482
798 CI62020 Acid Violet 41
799 CI62025 Disperse Violet 26
800 CI62030 Disperse Violet 8 000032337
801 CI&204S Acid Blue 62 004363S63
802 CI6205S Acid Blue 23 006408782
803 CI62070 Acid Blue 145 006408806
804 CI62073 Acid Blue 230
SOS C162030 Solvent Blue 13
806 CI620S5 Acid Blue 47 00440W98
-------
B-134
Process
No.
Process
Vnatcs
Waste
Tn-ntnu-nt
Total
_rroauction
Rof c
28
28
31
15,28
Aminolysla
Anlholysls
Aalde Formation
Sulfonation
Aminolysis
28
30
Aolnolysls
Condensation
30
Condensation
32
28
28
30
Nitration
Amioolysis
Aolno lysis
Condensation
28
15,28
Amlnolys Is
Sulfonation
Aminolyuls
Wator: brlu^u
contaInlii*', small
acuunts of organic
chemicals
Water: brines
containtng small
aoaunts of organic
chemicals
Water: brines
containing small
asiounta of organic
materials
Water: dilute
sulfuric acid
and brine
solutions
contaminated
with small
aoaunts of
organic chemicals
Water; brines
containing soall
aaounts of organic
chemicals
Water: brines
containing small
amounts of organic
chemicals and
possibly small
amounts of heavy
cetal ions
Water; brines
containing small
amounts of organic
chemicals and
possibly small
amounts of heavy
metal Ions
Air; nitrogen
oxide emissions
Water: spent
acid froa nitration
(e.g., sulfuric
acid)
Water: brines
containing small
amounts of oraganic
chemicals
Water; brines
containing small
amounts of organic
chemicals
I
Water: brines
containing small
amounts of organic
chemicals and
possibly small
amounts of heavy
metal ions
Water: brines
containing small
amounts of organic
chemicals
Water; dilute
sulfuric acid
and brine
solutions
contaminated
ulth acvill
amounts of
organic chcmlcaln
21.8 (48)-
1973
292 (642)-
1973
-------
Item
No.
CcMttpounJ
N;imo and
r.M-nvilo
li-135
TAliU: U-3. (Culitlimvil)
Chcm, AbBCr.
Registry No. Or:ll Toxlclty, Toxic H:mtrtl Kitting
LUSO- "H"1*' Airuttf CJii.Mili: Toxtcoloi-.v
T1.V
CflTClnoecq
807 CI62105 Acid Blue 78 006;.'4755
803 CIS2125 Acid Blue 40 006424857
809 C162130 Acid Blue 41 002666173
810 CI62SOO Disperse Blue 7 003179906
311 CI62560 Acid Green 41
812 CI63000 i=W Blue 43 002150609
813 O63005 Solvent Blue 74
814 CI63010 Acid Blue 45 002861021
815 CI63285 Disperse Blue 46 012217797
81$ C163365 Vac Violet 17 003076877
817 CI63615 Mordant Black 13
818 CI64500 Disperse Blue 1 002475458
819 CI64515 Acid Blue 81
820 CI65005 Acid Black 48 001328241
821 CI65049 ?lgmcnc Yellou 123
822 CI65230 Vot Black 9
-------
B-1 ?h
Source* of
Compound
Process
Process
A.iiiocl.-ited
Vault
Trratnvrt
Total
ProJu.'t ion
Reference*
IS
28
Sulfo-.tatlon
Aminolysla
Water; dilute
sulfurlc m:ld and
brine solutions
contaminated with
saall atixnutts of
organic chenlcals
Hater: brines
containing small
aoounts of organic
chemicals
14.6 (3.')-
1973
309 (6SO)-
1973
28
28
15
Anlnolysis
Atninolysis
Sulfoaatlon
Wat er: brines
containing scvilL
amounts of organic
chemicals
Water: brines
containing small
anoints of organic
chemicals
Water: dilute
sulfuric acid and
brine solutions
coatarainated with
small amounts of
organic chemicals
15.5 (34)-
iv/j
(359)-
1973
33
Nltrosation
Reduction
Sulfoaacion
Air: sulfur
oxides, nitrogen
oxides and hydrogen
sulfides
Water; spent
acids
41 (91)-
1973
31
15,28
32
15,28
15,28
31
Amide Formation
Sulfonation
Aoinolysis
Amide formation
Sulfonatlon
Aminolysis
Sulfonatlon
Amlnolysis
Amide Formation
Condensation
Water: brines
containing small
aoounts of organic
materials
Water: dilute
sulfuric acid and
brine solutions
contaminated with
spall amounts of
organic chemicals
Air: nitrogen
oxide emissions
Water: spent
acid from nitration
(e.g., sulfuric
acid)
Water: diluta
sulfuric acid and
brine solutions
contaminated with
scall amounts of
organic chemicals
Water; dilute
sulfuric acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Water: brines
containing small
amounts of organic
materials
Sj)ljd: copper
salts, sndfum
bromide nnd
distillation
residuea
104 (228)-
1973
-------
n-137
TAHI.K U-3. (iVntlmird)
Item
. So.
Compound
Name and
Form 11 ft .
Chen. Ahstr.
Registry No.
twin)
Oral Toxu-tly,
Toxicology
TLV
823 C165430 Solubtllii.-J Vat
Yellow 10
824 C167000 Vat Red 10 002379795
825 CI67300 Vat Yellow 2 000129099
826 CI67895 Vac Violet 14
827 CI58210 Solvent Red 52
828 C168215 Acid Red 80 00447S766
829 CI68420 Pigment Yellow 108
830 CI63700 Vat Violet 13
831 C16900S Vat Black 27 002379819
832 CI69015 Vat Broun 3 000131920
833 " Pigment Brown 28 000131920
834 CI69025 Vat Oranse 15 012379734
-------
ii-us
Sources of
Compound
Process
Associated
WllSf CM
Waste
Total
Product ion
Vsc-s
Reference*
31
36
36
28,12
28
12,15
31
28
28
28,37
Amide To mat ton
Reduction
Hydrolysis
Condensation
Cycllzatlon
Reduction
Condensation
Purification
Amlnolysis
Halogeaation
Amlnolysis
Halogeaation
Sulfonation
Amide Formation
Amlnolysls
Amlnolysis
Amlnolysis
Oxidation
Cycllzation
Purification
Condensation
Filtration
Water: brlnosi
contntnlns small
amounts of organic
materials
Wajter; brines,
spent sulfuric
acid and a sodium
thiosulfate
solution containing
small amounts of
organic chcntcols
Solid: distillation
residues
Water: brines,
spent sulCurie
acid and a sodium
thiosulfate
solution containing
small amounts of
organic chemicals
Solid: distillation
residues
Water; hydrogen
hallde and small
amounts of highly -
colored products
and brine with
small amounts of
organic chemicals
Water: brines
containing small
amounts of organic
chemicals
Water: hydrogen
hallde, dilute
sulfuric acid,
small acounts of
highly colored
products and brine
solutions
contaminated with
small amounts
of organic chemicals
Wa_t_er_; brines
containing small
amounts of organic
materials
Water: brines
containing ssnll
amounts of organic
chemicals
Water: brines
containing saall
amounts of organic
chemicals
Water: sulfuric
acid solutions
containing small
amounts of organic
chemicals, and
aqueous solutions
containing salt,
copper ion, chromium
ion, .and sulfate ion
1696 (3.732)-
1973
276 (608)-
1973
(377)-
1973
262 (577)-
1973
28,37
37
Oxidation
Cycllzation
Purification
Condensation
Filtration
Water; sulfuric
acid solutions
containing small
annum3 of organic
chemicals, and
aqueous solutlon.1
containing salt,
copper ion, chronluro
ion, n»*l Rulfatc ion
336 (739)-
1971
-------
B-139
TAIUJ: »-3. (co
Item
No.
Compound
N.
-------
B-140
Sources of
Compound
Process
Ho.
Process
Associated
Wnsti-s
Waste
Trv a tfuctu
Total
Product ton
Uses
28.34
15
28.34
22
33
Arclnolysi:)
Cycllzjtion
Condensation
Sulfonition
Aninolysis
Cycllzition
Condensation
Oxidation
Baking
Amide Format ten
Purification
Filtration
Wiit_or: brines
containing small
amounts of organic
ctu'tntcals
Solid! copper
salts, sodium
bronlde, And
distillation
residues
Water: dilute
sulturlc acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Water: brines
containing saall
amounts of organic
chentcals
Solid: copper
salts, sodium
brooide, and
distillation
residues
Water: brines
containing inorganic
sulfur compounds and
small amounts of
organic chemicals
Water; alkaline
solutions as
veil as sodium
sulfate
604 (1.329)-
1973
1.066 (2,345)-
1973
2)330, 117
IS
12
12
Sulfonatlon
Halogenacloo.
Water: dilute
sulfuric acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Wacer; hydrogen
halide and small
amounts of highly
colored products
12
12
15
15
35
Balogenation
Sulfocaclon
Sulfonatlon
Diazotlzaclon
Reduction
Cycllzation
Dlmorlzatlon
Ethylatlon
Water: hydrogen
halide and small
amounts of highly
colored products
Water; dilute
sulfuric acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Water; dilute
sulfuric acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Air: nitrogen
oxides and
possibly sulfur
dioxide
Water: spent
acid and brine
containing sre.lll
oraountu of organic
material!*
890 (1,957)-
1973
-------
h-141
TAULE B-3. (Vonclnuud)
Ilea N:ir,io iiml
No. Fonmiln.
Chen. Abstr.
Ki'Kistry No.
I'-'IJO
Oi'.il To.'cictcy, Toxic tins/ml Rtitinp.
U)yo. nin/Vs Ac,,u. cin-.M.U
Toxicology
TLV
849 CI70320 Vat Red 13
O0'.:03774
850 CI70507 Vat Blue 67
851 CI70600 Vac Yellow 1 000i75718
852 » Pigment Yellow 24 000-175718
853 CI70800 Vat Brown 1 002i75334
854 CI70801 Solubllized Vat . 023725157
Broun 1
855 CI70805 Vat Orange 11 002172330
856 CI71050 Vat Gresa 8 001499974
857 CI71100 Vat Red 15 004216028
858 C171105 Pigment Orange 43 OOU24060
859 Vat Orange 7 004424060
860 CI71110 Vat Red 14
361 CI71129 Plgsient Brown 26
862 CI71130 Vat Rud 23
005521313
-------
Source) of
" Compound
Process
No.
Associated
Unsti'S
Waste
Tren tnu-nr
Total
Product ion
Vau 3 '
Reference*
Di.izot Ization
Reduction
Cycllrjclon
Dlmorliatlon
Ethylation
Air: nitrogen
oxides and
possibly sulfur
dioxide
Woj^: spent
acid and brine
containing scull
amounts of organic
materials
127 (.'80)-
1973
38
38
39
IS
39
39
40
Condensation
Filtration
Condensation
Cyclizacion
Sulfonatioo.
Condensation
Cyclizacion
Condecsacion
Cyclizatioa
Amide Formation
Filtration
Wa_t«r: alkaline
solutions as
well as sodiua
sulfate
Mater: brines
coacaining copper &
alumtnuro ions, and
small amounts of
organic compounds
.Solid: distillation
residues
Water: dilute
sulfurlc acid and
brine solutions
contaminated vleh
small anounts of
organic chemicals
Water: brines
containing copper &
aluaiiaum ions, and
small acounts of
organic compounds
Solid: distillation
residues
Wacerr brines
containing copper &
aluainuQ ions, and
scall amounts of
organic compounds
Solid: distillation
res idues
Water: effluents
containing organic
cheoicals, acetic
acid, tt-phenylene-
diaaine, ethanol,
and potassium
hydroxide
Solid: distillation
residues
360 (792)-
1973
102 (224)-
1973
40
Amide Formation
Filtration
41
Amide Formation
Antlde Formation
Mcchyl.it Ion
Water: effluents
containing organic
chemicals, acetic
acid, (>-phenylene-
dlaniine, ethanol,
and potass iuzt
hydroxide
Solid: distillation
residues
Water: effluents
containing
alkali, sodium
sulfacc, and
organic compounds
!£?> cfflucntft
contaInln^
alkali, sodium
sulf.ito, and
or^^nfc compounds
-------
D-U3
TAHI.K B-3. (Contlmu-il)
Item
He*.
Compound
t>3nio and
Chum. Abate.
KKgtxcry No.
Oral Toxiiiicy, Toslc !!;\znrcl K.-itlm'.
t-l'sp. "-.g-kS Acute Chronic
Toxicology
TLV
Carcinogen^
863 " Pigment Red 179 005521313
864 CI71135 V.it ReJ 32 002379773
865 CI71137 Pigment Red 149 012225024
866 CI71140 Pignent Red 190 006i24777
867 Vat Red 29 006424777
868 CI71145 Pigment Red 123
869 CI71200 Vac Blue 16 006424766
870 CI71205 Vat Blue 53
871 CI73000 Vat Blue 1 000'4S2893
872 i. D&c Blue 6
873 CI73015 FD4C Blue 2
000-432893
000860220
T56 BMYVJ
C SVQ C-2U
S -SA-2
TDLo:10
211, TfX:C.«
scu-rac
874 * Acid Blue 74
875 C173065 Vat Blue 5
000860220
875 CI73300 Vat Red 41 000522753
877 CI73310 Pigment Red 87 006371115
878 CI73312 Pigment Red 88 014295433
-------
Sources oi
Process
Proccs.H
Associated
Waste
Trvacm.'tu.
Total
Produ.-c ion
Usos
Rtffcrencci
41
41
41
41
41
26
12
42
42.
15
15
12
43
45
45
Condensation
Hydrolysis
Amide Formation
Condensation
Hydrolysis
Amide Formation
Condensation
Hydrolysis
Amide Formation
Condensation
Hydrolysis
Amide Formation
Reduction
Condensation
Oxidation
Halogeaation
Amide Formation
Filtration
Alkylation
Hydrolysis
Sulfonation
Halogenation
Dlazotizatlon
Alkylation
Amide Formation
Oxidation
Substitution
Hydrolysis
AlkylatIon
Cycllzatlon
Hcrz Reaction
Hydrolysis
Alkylatlon
Cycltz.ition
Hcrz Reaction
Uattr: effluents
containing
alkali, sodium
sulfate, and
organic compounds
Hater: effluents
containing
alkali, sodium
sulfate, and
organic coapounda
Water: effluents
containing
alkali, sodium
sulfate, and
organic compounds
Water: effluents
containing
alkali, sodium
sulfate, and
organic compounds
Water: brines
vita excess alkali,
manganese ion,
or aluminua ion and
organic substances
Solid: oxide sludge
Water: hydrogen
halide and small
amounts of highly
colored products
Water: small amounts
of salts and
organic compounds
Water: dilute
sulfuric acid and
brine solutions
contaminated with
small aoounts of
organic chemicals
Water: hydrogen
halide and stnall
amounts of highly
colored products
Water: dilute
alkali solutions
and also sodium
chloride and snail
anoints of org.inic
chemicals and
nitrogen oxides
Solid: copper sulftde
Water: brine
contaminated, with
varying a counts
of organic
chemicals and
cyanide Ion
Water! brine
contaminated with
varying anounts
of organic
chetnJcnlH and
cyauitlc ion
37.7 (83)-
1973
2)330. 217
2)330, 217
-------
B-14S
TAItl£ n-3. (Continued)
Compound Chen. Abatr.
Item Niraa mid Registry No. Or;il Toxl^lty, Toxic llnznnl Xnrtng
So. Ft-rnuilii tKLN) **t'50' ";^'tl^ Acm» ClironK- ToxtcoloRV Tl.V C.ircti;
879 CI73335 Vat Or.tnge 5 003-63318
880 CI73336 Solublll:ed Vat 010126871
Orange J
3S1 C173360 Vat Red 1 002379740
832 " Pigment Red 181
883 " DiC Red 30 002379740
884 C173361 Solubillzed 003375727
Vat Red 1
885 CI7338S Vat Violet 2 005462293
886 » Pigment Violet 36 005452293
887 CI73390 Pigment Red 193
833 CI73395 Pigment Violet 33 002379751
389 ' " Vat Violet 3 002379751
890 CI73410 Vat Brown 5 003989751
891 CI73670 Vat Black 1 003687670
892 CI73671 SoltiblllzL-d Vat 010134357
Black 1
893 CI73915 Pigment RcJ 122 012225002
-------
K-Uti
Sources of
Process
Associated
Wnstcs
Way to
Trcotnu-nc
Total
.J'rodu.'t Ion
US.-3
Reference*
IS
Hydrolysis
Alkylatlon
Cycllrutlon
Hcrz Reaction
Sulfonation
Hydrolysis
Alky lac ion
Cyclizatlon
Herz Reaction
Hnj^r: brine
contaminated with
varying aoounts
of orp-inlc
chemicals and
cyanide ion
Wat_ejr: dilute
sulctirlc acid and
brine solutions
contaminated with
saill amounts of
organic chemicals
Water; brine
contaminated with
varying acounts
of organic
chemicals and
cyanIdo ion
141 (311)-
1973
45
15
45
Sulfonation
Hydrolysis
Alkylacioo
Cycliration
Herz Reaction
Water; dilute
sulfuric acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Water; brine
contaminated with
varying amounts
of organic
chemicals and
cyanide ion
45
45
44
Hydrolysis
Alkylatlon
Cyclizatioa
Herz Reaction
Acid Chloride
Formation
Reduction
AlkyUtion
Cyclization
Oxidation
Water: brine
coataoinated with
varying acounts
of organic
chemicals and
cyanide loo
Water: dilute
hydrochloric acid,
phosphorus oxy-
chloride, aqueous
zinc chloride
solution and
aluriinum chloro
hydrate solution
Solid; distillation
residues
44
46
15
Acid Chloride
Fo nut ion
Reduction
Alkylation
Cycllzatlou
Oxidation
Oxidation
Chlorlnation
Bromination
Condensation
Sulfonatlon
Water: dilute
hydrochloric acid
phosphorus oxy-
chlorlde, aqueous
zinc chloride
solutions and
aluminum chloro-
hydratc solution
Solid: distillation
residues
Water: brines
containing small
aootints of
organic chcalcals
Water: dilute
sulfuric acid and
brine Bolutlono
contaminated with
8E.il I nmouiUB of
organic chemicals
44.1 (97)-
1971
-------
Item
Ko.
B-l',7
TAIII.K 11-3. (CjiiUii.ii-J)
Compound Chen. Abulr.
[lame nnd RcEi.stry Uo. Oral ToxKllv. Toxic H:iBnrlRm.-i.t P.I no 27
-------
Source* of
^C
Process
Piv
Wn »11
Tn'-a tcn-iit
TotJl
Product Ion
Rofo
47
Chlorlwitlon
Condensation
Grinding
Acid Pasting
Water: relatively
lar>:c aiauunts of
uastc sul(uric
acid and brittle
blue pigment.
Also, brines
containing
altdluun ion
and sm.il! amounts
of organic
chemicals
2880 V6.336)-
1973
47
47
47
15
Sulfonacion
Water: dilute
sulfurlc acid and
brine solutions
contaminated ulth
small amounts of
organic chemicals
2033 (4,472)-
1973
(343)-
1973
15
15
47
Sulfooatlon
Condensation
Chloroae thyla tion
47
Chlorlnatloa
Condensation
Grinding
Acid Pasting
47
Condensation
Amide Formation
Reduction
Chlorosulfonatlon
Water: dilute
sulfurlc acid and
brine solutions
contaminated with
small amounts of
organic chemicals
Water: relatively
large amounts of
waste sulfuric
acid and bright
blue pigment.
Also, brines
containing
aluminum Ion
and small anounts
of organic
chemicals
Water; relatively
large amounts of
vaste sulfuric
acid and bright
blue pig-enc.
Also, brines
containing
aluminum ion
and small amounts
of organic
chemicals
Water: relatively
large ao*>unts of
vaste sulfuric acid
and bright blue
pigment. Also
brines containing
aluminum ion and
scall amounts of
organic chemicals
493 (1.085)-
1973
1740 (3,828)-
1973
-------
il-149
TAHI.K K-3. (Continued)
Item
No.
i
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
9iS
Confound Chen. Abatr.
N.-iuu' ond Rt'Ristry No. Ov;tl Toxlclty. Tuxlc lu/nrd K;irlnrr
Fomuln IVLN) LUiO' "*'k|; ACIIU- Clir.'iili: ToxlcoloRv
Pigment Blue 23 ~
Pigment Red 91
Pigment Red 170
Pigment Red 177 004051632
Pigment Violet 74
PM\ Pigment Red 79
Pigment Orange 38
Pigmeac Yellow 85 -- --
Vat Blue 39
Vac Blue 60
Vat Brown 11
Vat Green 32
Vac Green 20
Vat Brown 57
Vat Brown 40 '
Vat Brown 31 --
Vac Brown 29
Vac Brown 28
Vac Brown 20
Vac Brown 13 -- --
Vat Brown 12
Vac Black 13
Vac Black 22
Vat Black 34 ~
Vat Black 52
Vat Black 38
Vac Black 37
Pigment Yellow 76
Vac Violet 21 _ _ _
Vat Red 12 .
Vat Red 52
Vac Red 16
Vat Yellow 15
Vat Yellow 33
Vat Yellow 22 ~
Vat Yellow 14 ~ .
Lcuco Sulfur Brown 82
Lcuco Sulfur Brown 81 ~
Solvent Yellow 13 '
Solvent Yellow 40
Solvent Yellow 45
Solvent Yellow 44 00247K208
Solvent Yellow 43 012226969
Solvent Yellow 42
Mnrilant llt.ick 26
TLV . Cnrclnoi
_
_
_ _
__
.
_
_ _
_ _
_ _
_ _
_ _
_
_
_
_ _
_ _
-_
._
'_
__
_-
-------
Source;: of
Aiaocintctl
V.I !«f «'!!
Total
Pro.!uctton
-------
r.-i5t
TAr.u: u-3. (Continued)
Item
No.
Coapound
Kane and
rornnilo
Chem. Abalc.
Registry No.
(WLN)
0ml ToxUlty, T.'xtc l!;nnril Kiiilna
ToxtcoloEv
TIV
959
960
961
962
963
964
965
966
967
963
969
970
971
972
973
974
975
976
977
978
979
989
981
982
933
984
985-
986
987
983
989
990
991
992
.993
994
995
996
997
998
999
1000
1001
1002
1003
Mordant Slack 8
Mordant Brown 70
Mordant Brown 63
Mordant Orange 8
Mordant Red 64
Slordant Yellow 29
Mordant Blue 19
Ingrain Blue 3
Fluorescent Brighccner 159
Fluorescent Brlghtenar 158
FDSC Red 40
> Solvent Red 68
Solvent Red 33
Solvent Red 40
Solvent Orange 51
Solvent Orange 48
Solvent Orange 20
Solvent Orange 31
Solvent Orange 25
Solvent Orange 24
Solvent Oraage 23
Solvent Yellow 107
: Solvent Yellow 87
Solvent Yellow 47
Solvent Yellow 72
Solvent Yellow 71
> Solvent Blue 9
Solvent Blue 16
Solvent Blue 57
Solvent Blue 43
Solvent Blue 33
Solvent Blue 37
Solvent Violet 17
Solvent Red 166
Solvent Red 164
Solvent Red 103
Solvent Red 126
Solvent Red 115
Solvent Red 105
Solvent Red 75
Solvent Red 74
Solvent Red 69
Solvent Blue 60
Solvent Dine 53
Solvent Him- 100
025956176
-------
11-1 SJ
Sources of
ror.r.-und
Process
Associated
U'.TJTC.'i
Waste
Tn-atr-vnt
Total
Production
Rofercnce<
71.4 (157)-
1973
-------
11-15}
TAIlIJi B-3. (Continued)
Item
Ko.
Compound
Name titij
Formula
Chen. Abstr.
fa-glut ry No.
(Wlji)
Ornl Toxiclty. Toxlr i;.-i::nr>l K.iil
Llkn, ms/kj;
._Att"tf
Toxicology
TLV
. Cuvcinoi-.on
1004 Solvent Bluo 93
1005 Solvent Blue 89
1006 Solvent Green 2
1007 ~ Solvent Broun 11
1008 Solvent Brown 33
1009 -- Solvent Brown 22
1010 Solvent Brown 20
1011 Solvent Srovn 19
1012 Leuco Sulfur Yellow 15
1013 Solvent Black 26
1014 Solvent Black 17
1015 -- Solvent Black 13
1016 Solvent Black 12
1017 Leuco Sulfur Brown 3
1018 Solubilized Sulfur Brown 37
1019 Leuco Sulfur Brown 37
1020 Leuco Sulfur Blue 5
1021 Sulfur Blue 3
1022 -- Leuco Sulfur Green 16
1023 ~ Sulfur Green 14
1024 Pigoent Green 38
1025 Pigneat Green 48
1026 Pigoent Brown 32
1027 Acid Yellow 49
1028 Acid Yellow 59 001220529
1029 Acid Yellow 19
1030 -- Acid Yellow 79
1031 Acid Yellow 124
1032 Acid Yellow 114
1033 ~ Acid Yellow 152
1034 Acid Yellow 174
1035 -- Acid Yellow 159
1036 Acid Yellow 135
1037 Acid Yellow 129
1038 Acid Yellow 128
1039 Acid Yellow 127
1040 Acid Orange 2 -r
1041 Acid Yellow 198
1042 Acid Yellow 190
104} ~ Acid Yellow 179
1044 Acid Yellow 175
1045 Acid Blue 69 006370623
1046 -- Acid aiun 63
1047 Acid Blue 122
1048 Acid Blue 163
-------
Sources of rrocosi
Associated
font pa
Voice
Tri'nt*u'nt_
Totnl
ProJuction
l'50»
Rcf ercp.cc »
199 (438)-
1973
230 (505)-
1973
-------
TA11LE B-3. (Continued)
Item
KP.
Compound
Nam* flntl
Form i In
OUT.. Ahacr.
Reglslry No.
Oral Toxls'l'y, Toxic il.i?nrd R:itlnK
l"!>0- °y;UK Acnl.- CliivnU-
ToxlCO.lOKV
TLV
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1063
1069
1070
1071
1072
1073
1074
1075
1076
1077
1073
1079
1080
1081
1032
1033
1034
1085
1086
1087
1088
1089
1090
1001
1092
1093
Acid Blue 193
Acid Blue 179
Acid Violet 29
Actd Violet 76
Acid Red 337
Acid Red 309
Acid Red 299
Acid Red 278
Acid Rod 277
Acid Red 266
Acid Sad 225
Acid Red 213
Acid Red 212
Acid Red 211
Acid Red 119
Acid Red 100
Acid Red 167
Acid Red 175
Acid Red 178
Acid Red 182
Acid Red 191
Acid Red 194
Acid Red 57
Acid Orange 136
Acid Orange 132
Acid Orange-64
Acid Orange 62
Acid Orange 69
Acid Orange 128
Acid Orange 119
- Acid Orange 116
Acid Orange 86
Acid Black 29
Acid Brown 354
Acid Brown 243
Acid Brown 239
Acid Brown 158
Acid Brown 152
> Acid Broun 98
Acid Broun 97
Actd Brown 96
Acid Bl.ick 172
Acid Black 140
Acid Black 51
Acid B|;j<:k 53
012220267
012239053
012220074
012219040
012218949
-------
B-r.6
Source) of Process
C.*irp3»f.J No.
Process
Asaoclntcd
Mnr-trs
Wiute Total
Treiilm-nt ProJncllon
Vstt
Rcferrnces
127 (279)-
60.0 (132)-
1973
134 (295)-
1973
41.8 C92)-
1973
270 (593)-
-------
B-1W
TAIII.E B-3. (i\iiuliu.fi!)
Item
No.
J 004
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1123
1129
1130
1131
1132
1133
1134
1135
1136
1117
1138
Coaipoumt Clion. Abocr.
Name nnj RuKlstry Uo« Oral Toxivclty, Toxic K.-i'/nrtl RntlnK
. Formula- (WHO- ' L1ISO' rj*'k* Acuc.' Ur.vuU Toxii-oloRV
ActJ Slack 139
Acid Black 103
~ Acid Black 107 012213961 ~ -- ~
Acid Black 92 -- --
Acid Crecn 58 --
. Acid Green 84
Acid Creon 70
Actd Brovn 19 012234730
Acid Brown 28 _____ _
Actd Brovrn 22
Acid Brown 58
Acid Brown 51
Acid Brown 45 012219544
Acid Brown 31 ' ~
Acid Blue 221 .
Acid Blue 215 014541903 . -r-
Acid Blue 203 _
Acid Blue 293 .
Acid Blue 231 -- -- . '
Azoic Brown 9
Azoic Red 74
Azoic Blue 2
Azoic Blue 3
Azoic Red 73 x
Azoic Black 1
Azoic Brovn 26
Azoic Black 15 --
Azoic Black 4
Basic Blue 35 -- ...
Basic Blue 22 .
Basic Blue 21
Basic Blue 45
Basic Blue 45
Basic Blue 47 012217435 --
. Basic Blue 76
Basic Blue 75
Basic Blue 69
Basic Blue 60
~ Basic Vlolcc 24
Basic Violet 15
Basic Orange 41 ~
Basic Orange 40
~ Basic Red 14 ~ ~
Basic Ornnp.o 24
Basic Orange 26 ~ -- --
TLV Care!
_
_
--
_ '
-_
__
__
_ .
" -
_
_
_ _
_
-_
_
-_
_
--
-_
__
_-
_-
--
-------
II- I VI
Sources of Process
Cc»r-.?untl Xo,
Associated
Process
Waste
Total
Production
l'»c»
. Hcfercn.-ta
138 (303)-
197J
160 (352)-
1973
144 (517)-
1973
(559)-.
1973
-------
H-1V.)
TAUU: B-3. ((\milm.wi)
Item
No,
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150
1151
1152
1153
1154
1155
1156
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169
1170
1171
1172
1173
li74
1175
1176
1177
1178
1179
1180
1181
1182
1 181
Compound Chen. Abstr.
N»tno mid Registry No. Ontl Toxi^tty, Toxic tlaz.in! Snttnn
K.'ttmiln (I>'UN) '-U!>0' "i"** Aculo Cln'.-nU- TosU-olocv
-- Basic Orange 25 --
Basic Orange 39
Basic Orange 31 . __
Basic Orange 28
Basic Orange 27 _-
-- Basic Red 73
Basic Red 46 __ _
Basic Red 51 . _
Basic Red 49
Basic Red 23
Basic Red 22 _ -_ _
Basic Red 19
Basic Red 17 _____ _
Basic Red 16
Basic Red 15 _____ _
Azoic Coupling 3 --
Basic Yellow 15
Basic Yellow 13
Basic Yellow 21
Basic Yellow 31
Basic Yellow 29
Basic Yellow 28 '
Basic Yellow 58
-- Basic Yellow 53
Basic Yellow 52
Basic Yellow 41 __ _
Salt Azoic Diazoic 121
Reactive Blue 21
Reactive Blue 38 012236907
Reactive Blue 30
Reactive Blue 29 ~ -- --
Reactive Blue 25
Reactive Broun 17
Reactive Broun 10 ______
Reactive Brown 9 -- .
Reactive Green 6 __
Reactive Blue 91
Reactive Blue 90
Reactive Blue 89 --
Reactive Blue 71
Reactive Blue 3 012239371
~ Reactive Violet 1 ~ ~ --
-- Rcnctlve Red 105
Kcnctlvu Rril 94
Rcnctlvi: Ri-tl BO
TLV Cure!
-_
'
_
_
_
_
. . -
_
_
_ " _
_
_
_ _
,
_ _
_
_
_
_-
'
_
_ _
_
_
_
_
__
_
_ ' _
_
_
_
_-
-
__
-------
Source! of Process
Compound - No.
Associated
Wnatua
Waste
Trc-armrnt
Total
Prodiu't ton
Reference*
175 (385)-
1973
-------
It-II. I
TAHU: n-'J. (Continued)
Compound Chum, Abstr.
Item K.imc ond Registry No. Ov;il Toxt^lty, Toxtc Hninnl R.-II Ing
So. formula (WUD ' L"iO' "B^S , ,\rulo Cl.ioulc Toxicology TLV .
1184 Reactive Red 53 0^5310973
1185 Reactive Red 55 027873627 --
1186 Reactive Red 43
1137 -- Reactive Red 41 012226185 .
1183 Reactive Red 40 012226174
1189 -- Reactive Red 33
1190 Reactive Red 31 _ __ _ _
1191 Fluorescent Brightencr 49
1192 Fluorescent Brlghtener 45 -
1193 Fluorescent Brlghcener 33
1194 Fluorescent Brightener 25
1195 Fluorescent Brightener 24
1196 Reactive Black 9
1197 Fluorescent Brightener 22
1198 Fluorescent Brightener 8 ~
1199 -- Fluorescent Brlghtener 6
1200 Fluorescent Brightener 134
1201 Fluorescent Brlghtener 130
1202 Fluorescent Brlghtener 128
1203 Fluorescent Brightener 126
1204 - Fluorescent Brightener 125
1205 Fluorescent Brightener 114 012270518 .
1206 Fluorescent Srightener 109 --
1207 Fluorescent Brlghtener 108
1208 Fluorescent Brlghtener 102
1209 Fluorescent Brlghtener 75 012226969 ~
1210 Fluorescent Brlghtener 71
1211 Fluorescent Brighteaer 68
1212 Fluorescent Brightener 61 . -- .
1213 Fluorescent Brtghtener 59 -- .
121,3 Fluorescent Brightener 54
1214 Fluorescent Brlghtener 52
1215 -Disperse Black 9 001222694 '
1216 Disperse Black 34
1217 Disperse Black 33 _ _
1218 Reactive Yellow 4 012226458
1219 Reactive Yellow 3 006539679
1220 Reactive Yellow 2 016893484
1221 Reactive Yellow 1 0050S9167
1222 Disperse Brown 14
1223 Dlspornc Brown II
1224 Disperse Brown 8 --
1225 Dlnpcrbe Brown 7 «
1226 Ulnpu-ruc Brovn 5
1227 Dlapurni: llroun 2
-------
Source? of Process
Associated
V«s to*
Waste Total
.Trvat-iont Production
References
-------
ll-ll'J
TAUI>: 11-3. (Continued)
Item
So,
i:28
1229
1230
1231
1232
1233
1234
1235
1236
1237
1238
1239
1240
1241
1242
1243
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253
1254
1255
1256
1257
1258
1259
1260
1261
1262
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272
Compound Choc. Abatr.
Name nnd Rvglmry No. Or.il ToxUUy, Toxic H.i:nr>l S.-.tlns
Fortmilo IWLX) '-"SO' n'i>/llK Acut,. Chuv.U- Toxicolov.v TLV P.,,
Disperse
Disperse
Disperse
Disperse
Disperse
-- Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
-- Disperse
Reactive
Reactive
Reactive
Reactive
-- Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
Reactive
~ Reactive
Reactive
Reactive
Reactive
-- Reactive
Dlspnr.se
-- Disperse
Disperse
Dlnper:
Dlr.pcrric
Blue 173 -- . .
Blue 172 .- . ...
Blue 166 ~
Blue 165 '
Blue 155 -,
Blue 152 _ _
Blue 150
Blue 148 _
Blue 139
Blue 138
Blue 133
Blue 132 '
Blue 125 -- --
Blue 123
Yellow 15 .
Yellov 7
Yellow 6 . 012239484 _ _ _
Yellow 25 012226527 ~ ~
Yellow 24 012226516 '
Yellow 18 . .
Yellow 17 020317195 ' -- '
Orange 5 -
Orange 4
Orange 1 006522743
Yellow 86 -
Yellow 62 --
Yellow 42 . -- .
Yellow 37
Yellow 31
Red 2 012226038
Red 5 «
Red 11 .
Red 29
Red 21
Orange 50
Orange 49
Orar.ge 14 0122258&4 ~
Orange 13 --
Orange 12
Orange 11 ' .
Violet 57 ~ . --
Violet 44 --
Violet 43
Violet 42
VIolKt 41
-------
Sources of Process Associated Wa»:e Totnl
Crr-".»i!nd No. Troccsa l-.'natc» Trynt-wnt ProJiK-tton Vtea »i-fgrcr.'f»
-------
TAI)1£ H-3.
Icon
N'n.
Compound
N.iau; nnd
Clion. Abntc.
Ri'RiMry No,
Oral ToxUlly. Tc'xtc l!;i/nfd K.ntln
i"l'..'^ Aciit.- r.tir.-nlc
Toxi colony
TLV
1273
1274
1275
1276
1277
1273
1279
1230
1281
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291
1292
1293
1294
1295
1295
1297
1293
1299
1300
1301
1302
1303
1304
1305
1306
1307
1303
1309
1310
1311
1312
1313
1314
1315
1316
1317
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Disperse
Diopcrse
Dl»pcr»e
DlRpersc
DlspufMe
Violet 40
Red 211
Violet 17
Violet 27
Red ISO
Red 179
Red 17S
Red 177
Red 175
Red 157
Red 162
Red 161
Red 159
Red 140
Red 139
Red 133
Red 137
Red 136
Red 135
Red 133
Blue 60
Blue 62
Blue 61
Blue 71
Blue 70
Blue 64
Blue 8
Blue 35
Blue 55
Blue 54
Blue 121
Blue 120
Blue 119
Blue 118
Blue 117
Blue 116
Blue 112
Blue 109
Blue 102
Blue 95
Blue 94
Blue 87
Blue 85
Blue 81
Blue T>
012222752
01227W8
-------
K-K.R
Sources of
Process
No.
Antedated
V'a.< tea
Wnice
Trrotri-nt
Tcuil
Product ton
Uaca
References
86.4 M90)-
197J
214 (471)-
1973
fi-'i'. O.f.19)-
]'/73
-------
n-1 c.;
TAIII.K 11-3. (Continued)
Item
No,
1318
1319
1320
1321
1322
1323
1324
1325
1326
1327
1328
1329
1330
1331
1332
1333
133A
1335
1336
1337
133S
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348
1349
1350
1351
1352
1353
1354
1355
1356
1357
1358
1359
1360
13 Disperse Orange 89 --
Disperse Ornnge 80 "~
Disperse Ornnge 79
Disperse Orange 73 --
Disperse Orange 77 -~
Dlnporao Orange 75 ~~
DlnprfHo Ornnge 67 --
Ulsnerr.c Or-in^i! 66 - __ ,
TLV Citrclnottcn
~
_
' _
_ _
.
_- ' _
_
--
_ _
__
_ -
.
_
_
_-
_-
-_
_-
._
_
_-
-_
-------
H-Ihci
Sources of Process
Compound So.
Protean
Aasociatud
Ba»tc»
Waste
Trratnfnt'
Total
t'aca
Rofo
145 (319)-
1973
311 (6851-
1973
51.4 (1131-
1973
-------
B-16'J
TAKIK li-'J. (Continued)
It«n
.NO,
1353
1364
1365
1366
1367
1368
1369
1370
1371
1372
1373
1374
1375
1376
1377
1378
1379
1380
1381
1382
1383
1384
1385
1386
1387
1388
1389
1390
1391
1392
1393
1394
1395
1396
1397
1393
1399
1400
1401
1402
U03
1404
1405
1406
1407
Compound Chen. Abstr.
Naac onJ Ruslstry No. Onil ToxUlty. Toxic ll.ii-.nrd K.iilnr
KornuU (UlN) ioW "*"> Acuto Cl.ivnU- Toxlcolow
-- Disperse Orange 65
~ Disperse Orange 62 --
Disburse Orange 59
Disperse Orange 58 -- __ .
Disperse Orange 57
Disperse Orange 44 -- _
-- Disperse Orange 42 .
Direct Blue 91
Direct Blue 100
Direct Blue 104
Direct Blue 143
Direct Blue 160
Direct Blue 191
Direct Blue 139
Direct Green 69
Direct Creen 47
Direct Creen 45
Direct Green 27 ' .
Direct Blue 199
Direct Blue 263
Direct Blue 224 .
Direct Blue 80 .
Direct Blue 24
Direct Violec 67
Direct Violet 99
Direct Blue 6 002602462
Disperse Yellow 34 .
Disperse Yellow 33 012223846
Disperse Yellow 32
Direct Black 95
Disperse Yellow 2
Direct Black 190
Disperse Yellow 67
Disperse Ycllov 69
Disperse Yellow 68 012223891 ~
~ Disperse Yellow 50 --
Disperse Yellow 58 '
Disperse Yellow 56
Disperse Yollow 93 --
Disperse Yellow 89
Dlspcrao Yellow 88
Disperse Yellow 87 --
-- Disperse Yellow 86
UlupiTne Yellow 85
Dlnpvrnc Yellow 77.
TLV
--
~
~
~
'
'
.
~
~
-------
B-170
Sources of Process
Proccns
Associated
V.ntea
Waste
Total
Product ton
Uses
52.7 (116)-
1973
239 (526)-
1973
54.1 (119)-
1973
130 (285)-
1973
-------
Item
No.
1403
1409
1410
1411
1412
1413
1414
1415
1416
1417
1413
1419
1420
1421
1422
1423-
1424
1425
1426
1427
1428
1429
1430
1431
1432
1433
1434
1435
1436
1437
1438
1439
1440
1441
1442
1443
1444
1445
1446
1447
1443
1445
1450
1451
U-171
TAI'.U: B-3. (Continued)
Compound Chcm. AbHtr.
K.inic anj RonUtrv No. Or.il Toxic. tly. TJxK- ll.nsnrcl Sadni;
Forrailn (WIN) LU30' "W^K Aculv Clir.'uic ToxtcoloKV TLV
-- DlapcrM Yellow 74 012J36338 ~ ' .
-- Direct Broun 48
Direct Brown 111
Direct Brown 40 - -
Direct Brown 1 003SU710
Direct Black 37
Direct Black 44 --
Direct Brown 213 ~
Direct Black 3
Direct. Yellow 39
Direct Yellow 23
Basic Black 9
Basic Green 7 ~ --
Basic Blue 97
Basic Green 3
Basic Blue 94
Basic Blue 87 _____ __
Basic Blue 82 '
Basic Blue 77 --
Direct Yellow 63 T-
Direct Yellow 105 --
Direct Yellow 103
Direct Yellow 84
Direct Yellow 81 .
Direcc Yellov 107
Dtrecc Yellow 117
Direct Yellow 114
Direct Yellow 127
Direct Yellow 120 ~ __
Direct Yellow 119
Dlrecc Yellow 118
Direct Orange 11 '
Dtrecc Yellow 137
Direct Yellow 133
Direct Yellow 132 -- '
Dlrecc Yellow 131
Direcc Red 100
Dlrecc Red 139 ~ .
Direct Red 238 -- --
Direct Red 236 --
Direct Red 209
Dtrwc Red 95 ~
Direct Ornngc 59
Direct Orange 72
Cnrcli
-
-
-
-
-
-
-
-
-
' -
-
-
-
-
-
_
-
-
. -
-
-
-
-------
K-I7J
Sources of
Process
Xc.
Process
Associated
Wa s t ^ a
Waste
Total
Pro.'uctlcn
Uses
Ri'fc-rfnccs
17.7 (39)-
1973
119 (262)-
1973
69.1 (152)-
1973
311 (685)-
1973
IA>. (125)-
1971
-------
11-173
TAIII.K H-3. ((Viitlmii-il)
I turn
No.
1452
1453
1454
1455
1456
1457
Compound
NAKIO unJ
Formula
-- Direct Orange 67
Direct Orange 81
~ Direct Orange 80
Direct Orange 79
~ Direct Orango 78
Direct Orange 110
Chon. Ahstr.
RcKlntry No. Or:il Toxlclty, Toxic llnKnr.l Ruling
(HI.N) U)50- mS'kl'. Acini- Cl, ionic Toxtcolo«v TLV Carcli
_ _ ' _
1453 Direct Orango 88
-------
B-17-'.
Sources of Process
Compound No«
Vusce
Ptvcesa
ToCrtl
Product Ion
Reference*
-------
n-r/5
TAIIIE B-1. ORGANIC UVKS AND MCMilSTS. IWKCANICS-TOXICITY
It via.
No.
1
2
3
4
5
6
7
8
9
10
11
12
13
.14
Coupouud
Name and
Formal:!
Alumina hydrate
Aluminum* acutatc
Aluminum sulfate
Ammonium bisulfite
(Araaonlum hydrogen
sulflte)
Ammonium molybdate
Arsenic trioxide
Barium chloride
Boric acid
Chlorosulfonic acid
Chromlua fluoride
Chromium formate
Chromium sulfate
Cobalt acetate
Copper (powder)
Clicm. Abstr.
Registry No, Oral Tor.K'ltv, Toxic 1'nriinl R.ittnv. ^^
(VLN) L"jO- ""'*& Ac ii 1 1-
l)irr-l
S)0
010043013
(AL2 S-02-
Q2* 3)
L)irr-3
ing-3
lnh-1
S)U
013106768 333 orl-rat L) irr-2
inf-2
inh-2
S)ing-2
001327533 20 orl-rat L) irr-2
(.As2.03) alr-2
lng-3
S)ing-3
lnh-3
010351372 L)irr-l
(BA C2) lng-1
inh-1
S) lng-3
lnh-3
010043353 2660 orl-rat L)ing-2
(QBQQ) lnh-2
S)U
007790945 L)irr-3
(H S-03 C) ing-3
lnh-3
S)U
LDLo-.lSO og/kg L)irr-3
orl-gpg lng-3
lnh-3
S)U
L)lrr-3
lng-3 .
lnh-3
S)n
010101533 L)irr-3
(CR2 S-02- ing-3
Q2* 3) lnh-3
S)U
000071487
(QV1 & QV1
& -CO-)
-- L)irr-l
alr-1
ing-1
inh-1
S) inZ-l
inh-2
CliroEiU
L)irr-i
S)0
L) irr-2
S)U
L)irr-l
S)lr.g-l
L) irr-2
alr-2
S) lng-3
inh-3
L)irr-l
S)ing-2
inh-2
UO
S)ing-2
inh-2
skn
abs-2
L) irr-2
inh-2
S)U
L) ing-3
ina-3 '
S)ing-3
inh-3
L) ing-3
ioh-3
S)iag-3
inh.-3
L)ing-3
inh-3
S) ing-3
inh-3
L) alr-1
S) lng-1
inh-1
Toxlcolor.v . TLV Care Inocct^^l
_ _
U>50 270 mg/kg
Inr-mus
No cases of hu=an USOS alr:WA 10.2
poisoning have been mg/zj
reported
A rodentlslde USOS alr:TWA 0.5
LD5Q 54 mg/kg USDS air.-TWA 806
ipr-mus ug/o3
USOS air:TCA 0.5
mg/n3
TDLo: 8 ga/k
SOW TFX:S£0
Ivg-mua
Highly toxic ~
LDLo:85 mg/kg
ivn-mus
LD50: 25 i-.g/kg
ivn-rbt
-
15 Copper ferrocyanlde
16 Cupric chloride
17 Cupric oxide
13 Hydrochloric acid
19 Iodine
001344678
007M7010
(11)
140 orl-rat
900 orl-rbt
I.DI.O-.2000
orl-hmzi
Used as a herbi-
cide
Used as a fungi-
cide
Dlrr- 3 Oirr-2
S)ln?-3 S)U
lnh-3
L)trr-3
S)ln;?-3
lnh-3
USOS alr:WA
og/m3
USOS air:TUA 5
ppo
t'ROS olr:TWA 0.1
ppm
USOS alr:-T.;A 1
mg/nJ
-------
11-176
meows.'WASTE, nioDuerioN AN» USE DATA
Sources of Process
Process
Aasocioled
Wnsti-s
Wuscc
Total
Production
Rjfi-rciK-c.i
3)373
2)59
3)377
3)463
2)750
3)393
2)126
3)422,420
2)148
3)432
2)231
3)467
2)320
3)555,1134
2)328
3)559
3)559
2)323
3)559
2)16
3)574
2)344
3)573
3)575
2)619
3)616
2)645
3)18. 832
-------
Item
20
21
22
23
') 24
25
27
28
29
V 30
31
32
33
34
35
36
37
Compound
N.irao and
Formula
Iron (r.crup)
Lead carbonate (basic)
Lead peroxide
Magneslun oxide (funo)
Manganese chloride
Manganese dioxide
Mercuric oxide
Nickel acetate
Raney nickel catalyst
OleumCsulfuric acid)
Phosgene
Phosphomolybdlc acid
Phosphorus oxy chloride
Phosphorus pcntachloride
Phosphorus trichloride
Phosphocungstlc acid,
sodlutn salt
Pot.issium carbonate
(anhydrous)
Potassium hydroxide
Chem. Abstr.
Registry No.
(UI.N)
000598630
(QViJ & -PB-)
001309600
001309484
007773015
(MN 02)
001313139
001344452
000373024
(qvi 4 2
-NI-)
007440320
(.NI)
007664939
(WSQQ)
000075445
(CVC)
010025373
(P 0 C3)
010026138
(P C5)
007719122
(P 03)
001303726
001310583
: _
LD^Q, IHK/KK Acute
DO
S)lnh-l
DO
S)lng-3
inli-3
DO
S) lng-3
lnh-3
Dlrr-1
S) lng-1
lnh-2
L)U
S) lng-2
inh-2
L)U
S)ing-2
lnh-2
18 orl-rat L)irr-l
S) ing-3
lnh-3
350 orl-rat
2140 orl-rat L)irr-3
ing-3
inh-3
S)U
L)lrr-3
inh-3
S) inh-3
380 orl-rat L)lrr-3
S) lng-3
lnh-3
660 orl-rat L)lrr-3
S) ing-3
lnh-3
550 orl-rat L)lrr-3
S) ing-3
lnh-3
1600 orl-rat Dlrr-3
S) lng-3
LDI.o:160 me/kg L)lrr-2
orl-r.it lng-2
S) lng-2
365 orl-rat L)lrr-3
lng-3
lnh-3
S)lni;-3
Chronic
S) lnh-3
DO
S) lng-3
lnh-3
skn
abs-3
DO
S) lr.g-3
lnh-3
skn
abs-3
Dirr-2
L)D
S) lng-3
lnh-3
L)U
S) ing-3
Inh-3
L)irr-2
alr-3
S) ing-3
inh-3
skn
abs-3
L)U
S)B
DU
S)D
-
L)irr-2
S)U
Dirr-2
S)U
Dtrr-2
S)U
L)irr-2
S)U
L)lrr-2
S)ing-2
L)lrr-3
S)U
Toxicology TLV
USOS nlr:TOA
253 ug/m3
USOS alr:TOA
230 ug/o3
TCLo:400ag/m3 USOS alr:TVA
TFX:UNS ihl-hmn 10mg/a3
tOLo:210og/kg
scu-mus
LD5o:121 agAg
ipr-mus
LBLo:45 ng/kg
ivn-rbt
Highly toxic USOS airrTVA
0.05 mg/m3
USOS air: TWA '
TDLo:15 mg/m3/ USOS air:WA
91WI, inh-gpg 1 mg/m3
TCLo:800 ug/m3 USOS alr:TWA
TFX_MTH , ihl-Jimn 1 ag/m3
: TCLo:350 ug/a3.
TFX:PUL, ihl-hon
TDLO-.25 ppn/30H
TFX:IRR, Ihl-him
LC5Q:75 ppra/
30M, Jhl-rat
Highly toxic
LCI.o:120 ppa USOS alr:TWA
Ihl-mus, highly 1 r.g/°3
caustic
LCLo:600 ppm/lOM USOS airiTVA
Ihl-mus 0.5 ppo
USOS air:TOA
3 mg/m3
Strong caustic
USOS air: TWA
Cnrclimeo^^fc
w
Iron compounds
suspected car-
cinogens
TOLo:350 og/kg/
43WI. IFX:CA^
ics-rat ^^^
TDLo:15 mg/kg7
6WI, TFX:SEO
scu-rat
~*
w.
~~
-------
B-17S
Sources of
CouuvunJ
Process
No*
Ausocintcd
Waste9
Wnste
Ttvntincnt
Total
ProJuct ion
References
3)336
2)677
3)861
2)677
3)861
2)6(56
3)19. 880
2)690
3)885
2)690
3)835
3)19. 895. 900
2)790
3)954
2)790
2)1096
3)985
2)837
3)1021
2)924
3)1025. 816
2)897
3)1025, 816, 7.1
2)924
3)1027. 816. 21
2)924
3)1027
2)950
3)1042
2)951
3)1047. 21
-------
I ten
No.
^d
JO
39
40
41
42
43
44
45
46
47
43
49
50
51
52
53
54
Nm:ic and
Kornula
Sodium bisulfite
Sodium bror.uce
Sodlun chlorate
Sodlua hyposulfite
Sodiua nitrite
Sodiua thlosulfate
Starmous chloride
SCronclua chloride
Sulfamic acid
Sulfur
Sulfur chloride
Sulfur monochloride
Sulfuryl chloride
Thionyl chloride
Zinc
Zinc chloride
TAIiia
Choni. Al'Str.
RrtU*'t<*y No. Ortil Ti'X.Ltjtty,
(KI.N) ^'':iO* I:-J"'^!P-
0077'J26't7 1090 orl-r:tt
(.KA.. MX-Oi)
00761UW5
(NA S-O-QZ)
0077893SO
(NA E-02-Q)
007775099 L01.o:1500 r.s/kg
(NA C-02-Q) orl-rat
007632000 85 orl-rat
(NA N-O-Q)
007772993 700 orl-rat
(SS C2)
010476354
(.SR..G2)
005329146 1600 ug/kg
(2SHQ) orl-rat
007704349
(S)
010025579
(S2 C2)
010025679
007791255
(S 02 C2)
007719097
(S 0 C2)
._
007646857
(.ZN..C2)
II- 1 /-I
"*' "'"": "J)
T.'xli- C.irnril P.iCiiii;
A.-iili Cl.ro:H»-
K) i rr-3 I.) i rr-2
lnr.-.l S)!n,;-3
in!i-.l lnli-3
S)liiK-3
inli-3
I.) Inc.-: U U
lull-: S) 1 :1S- 1
S)ini;-^ inh-1
inn-:
L)ll t.)U
S)liif- b:)inK-;
LHri- l.)irr-2
S)Iil|;- ?)U
inh-
L)inB- UU
inh- S)ir.s-l
S)lnfi- inh-1
inh-2
L) U L) U
S)ing-3 S)ir.g-3
inli-3 inh-3
L)irr-2 L)U
S)ing-2 S)U
inh-2
LHrr-2 L)U
S)U S)U
~
L)irr-3 L)irr-2
ing-3 inh-2
lnh-3 S)U
S)U
L)irr-3 L)irr-2
ing-3 inh-2
inh-3 S)L'
S)U
Irxlcoloi-.y Tl.V Ci.ri'l.n.v-..-
uf.'lj;!)0-!./!^
jn»:j«^.
U^ed as an -
hcrhi.-iiie
Host thiosulfates
have lov toxlcity
USOS air:TUA 3.2
mg/o3
ID5;).-?03 eg/kg
ior-cus
Very low
LCLo:15D p?n/l.M uso3 air:TWA 1 ppo
ihl-i^js USOS air: TWA 6 mg/
n3
LCLo::50 p?n/l.M USDS air:WA 1 ppn
ihl-cus US03 air:Tn'A 6 og/
m3
Corrosive
Very toxic material
and constitutes
serious toxic
hazards
Not toxic unless
heated
Tunes ate highly USOS air:TWA 1 TOLo:17 c
toxic . mg/o3 TFX:N£0,
o3/3C:M TFXtP'JL
ihl-r^m
LOLo:30 o;/kg
ivn-rat
-------
Sourct'K of
Process
... ""
Process
Wnsi.-.-i
V'iistu
Tn jigi-.
Torn!
rml-.:>;t lor.
2)846
1)1051
2)1052
2)23-',
3)471
2)J06
3)1105
3)1111. 1131
2)801
3)962, 1114
3)1120
2)1133
3)1124
2)1082
2)1088
3)1130
2)1096
3)1132
2)1096
3)1132. 21
2)1096
3)1132. 21
2)1098
3)1136
2)1126
3)1166
3)1252
2)1206
3)1251. 22
-------
TAHI.K H-'I \:>:i:'::i'ii:!
li-1 HI
No,
N:ntf mill
tV-.-ir.iilu
rlu-r.i. Abnlr.
'l!>.-)-.lstry Co.
Ur.-iL Ti'Mli-.lIy, 'ft'Si
'' ''
Il;i7.'iril H.n li
JOa CIU270 Solvent Or-ingc 3 000512321*
54a CIi:070 D;irk Plgmonc Rod 1 OOM10102*
98a CI13091 Acl.I Ocango 1
U7a CI15530 l..iko Pigment
Orange 7
175a CI16150 Laki Acid Red 26 003761533*
176a CI161SO Lake Aoid Red 17 005558333*
238a CI19140 Lake AclJ 001934210*
Yellow 23
251a CI20195 Plj^enc Acid
Brown 1A
358a CI27201 Acid Red 115 006226803*
367a CI2S160 Pigment Direct 002610119
Red 81
5ila C140000 Ptgnent Direct 001325377
Yellow 11
Tl.V
542a CI40001 Pipaent Direct
Yellow 6
001325388
J59a CI41000 Pigaent Basic
Yellow 2
002465272
561a CI41001 Pipaenc Basic 006358367
Yellow 37
563a CI42000 Fugitive Pigaenc 000569642*
Green 4
5S7a CI42025 Plgaant Basic 003521060
Blue 1
532a CI42093 D6C Blue 1
002650182
-------
U-Hi.'
Process
Asscol.it. >)
Waste
Total
ri\u!tt^ t U
6,18
6,18
6,18
Dla.'Ot Izat Iim
Coupling
niazottT.it Ion
Coupling
Dlnzotlzatlon
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Diazotization
Coupling
Condensation
Precipitation
Filtration
Condensation
Precipitation
Filtration
Condensation
Filtration
Precipitation
Condensation
Filtration
Precipitation
Condensation
Oxidation
Crystallization
Filtration
Condensation
Oxidation
Crystallization
Precipitation
Filtration
Condensation
Crystallization
Oxidation
Flltrjtlon
W.'.t.or:
b.llt.S
1973
(87)-
s.i Us
W.-iror: inorganic
salts
Wjit.cjr: inorganic
salts
Water: Inorganic
salts
Water: inorganic
salts
Water: inorganic
salts
Water: inorganic
salts
Bater: inorganic
salts
Water: brines
containing small
amounts of organic
materials
Water; brines
containing small
amounts of organic
materials
'Water: brines
contaminated uith
small amounts of
organic materials,
residual amounts of
metal ions and
lead sulfate
Water: brines
contaminated with
small amounts of
organic materials,
residual anounts of
metal ions and
lead sulfate
Water: brines
contaminated with
SMll amounts of
organic materials
Also, lead sulfate
is precipitated
as a solid waste
Water: brines
contaminated vith
small amounts of
organic cmtorlals,
residual anounts of
aetal Ions and
lead sulfate
Water: brlnus
cuutcinln:itcd with
small amuunts of
and le.id sulf.iti:
is preclplt.iti'it
a.i a solid w.-iste
90.9 (200)-
1973
2)330. 80
-------
I- -i!il
TAMl>; « -I. (C,ur lum-.l)
Cor.ipound
t'oriml.i
Chrro. Ah:-1 i .
Ki-glsrry No.
(WUO
Ornl Toxi i-.tr/.
Vlolot 2
593a CU2535 Fugitive
Violet 3
00030«S73
619a CI427SO Lake Acid Blue 93 028983564
632a CI45160 Lake Figment Red 81 0009S9388
6363 CI45170 Fugitive Pigment 001326030*
Violet 1
655a CI45430 FD&C Red 3
000568638
(T C566 BO
EVJ DI FI IR
BV04 LI MO MI
SNA- 2)
1895 orl-rat
LDLo:200 ng/kg
ivn-rat
719a CI53290 Sulfur Black 11
739a CI58055 Lake Pigment
Violet S
746a CI59300 Plg=ent Vat
Orange 3
004378614
749a CI59710 Pigment Vat
Orange 4
001324330
657a Cl71100 Pljr^nt Vat Red 15 004216028
-------
8 U'v
Sources of
Cotnppun.l
Process
No.
Associated
Total
Product ton
Uses
References
Oxidation
Filtration
Oxidation
Filtration
Benzylotion
Air: possibly
significant and
hazardous amounts of
toxic arylasines
Water: brines
contaminated
with varying
aaounta of organic
substances
Solids: sludges
containing large
amounts of netal
ions
Air: possibly
significant and
hazardous amounts of
toxic arylaoincs
Water: brines
contaminated
vith varying
anounts of organic
substances
Solids: sludges
containing large
amounts of aetal
Ions
265 (582)-
1973
Condensation
Cy dilation
Oxidation
Hater; brines
contaminated vich
snail amounts of
organic chenicals
Solid; sludge of
iron oxide
11,18
12,18
22
Precipitation
Filtration
Condensation
Precipitation
Filtration
Kalogenatlon
Condensation
12
12
Halogenation
Halogenatlon
Amide Formation
Filtration
Vatar: brines
contaminated with
small aoounes of
organic chemicals
and residual amounts
of octal ions
Solid: sludge of
iron oxide
tfater:
halide and small
amounts of highly
colored products and
residual acounts of
metal ions
tfater! brines
containing inorganic
sulfur compounds
and small aaounts
of organic chemicals
Vater; hydrogen
halide and small
amounts of highly
colored products
Vater: hydrogen
halide and saall
ai2ounts of highly
colored produces
Vator; effluents
containing organic
chcalcals, acetic
acid. £-[>hcnylcne
diamine. cthanul,
and potassium
hydroxide.
Sp_M_
-------
r.- i.Vi
TAKUi 11-J. (I'..I.: I inn-.!)
Clii-iii. Alis 1 1 .
Item Nun.- HI-..! Kcf.Utry lie. I'r.il To\i.;lty, Ti-sl. l!:i::iii-.l k.-il i
Sj. _ y.".'"-".'.-.' _ tHi) _ '.I':.Q. ':'./':. _ A^i.l.' '"c!,,vuU
8JSa CI7H05 rif.in-nt V.it
Oran^r 7
910;i CI76-.I76 I'sM.ilU-n B:ise 8
-------
Sources ot Process
To uil
rt'.iiu-t ton
llsca
-------
2 !?7
TA!'!>: I'.-'i. OiiCAXIC I'VKS AMI ruiKKNTS,
C«l.i|>i>uud CIt.-ITi. Alolr.
It.TI . K;ini.' mitl Roj'.tstry No.
No. Ki.riai.hi (WL::>
1 Aluptn;i liydr.itc
2 Alumtnvun acetate
') A lien inum ::ull.il.u OHIO i Illl'l
(A!..: s ,).:-
l}-* 3)
4 Anunonium hUulflte
(Action lun hydrogen
sulfKe)
5 Acnonlua motybJate 013106763
6 Arsenic trioxide 001327533
(.As2.03)
7 Barium chloride 010361372
(BA C2)
8 Boric acid 010043353
(QSQQ)
9 Cblorosulfonic acid 007790945
(H S-03 C)
10 Chrooiua fluoride
11 Chrooiuoi fomace
12 Chroaium sulface 010101538
(CR2 S-02-
Q2* 3)
13 Cobalt acetate 000071487
(QV1 4 QV1
& -CO-)
14 Copper (powdar)
15 Copper ferrocyanlde
1', Cuprlc chloride 001344678
17 Cuprlc oxide
18 Hydrochloric ocid 007647010
(Gil)
19 Iodine 00 7 S5 3562
(U)
''lit ^''X V'L '. ^' ' iil!i'/--l:d-:'jl
l.)ln-l
S)0
~~
L)irr-3
itii;-3
lnh-1
S)U
333 orl-rat L)irr-2
lni'.-2
lnb-2
20 orl-rat L)irr-2
alr-2
inp.-3
S)lnS-3
inh-3
L)irr-l
lng-1
inh-1
S)ing-3
Inh-3
2660 orl-rac L)ing-2
inh-2
S)U '
L)irr-3
ing-3
inh-3
S)U
LDLo:lSO' og/kg L)irr-3
orl-gpg ing-3
inh-3
S)U
L)irr-3
ing-3
lnh-3
S)U
L)lrr-3
ing-3
lnh-3
S)U
-,~
L)lrr-l
alr-1
inp-1
lnh-1
S)inE-l
inh-2
140 orl-rat
900 orl-rbt I.)irr-3
lnh-3
l.IH.o:20fiO L)lrr-3
orl-limn S) tnp.-3
inh-3
r.l K;u 1 iv.- . ^^
.'
S)ll
I.H-,,1 .',.> B!-..-1.!-.
Uirr-: --
S)U
t.)icc-l No cn^cs of hurun USOS atr:7.*'A 10.2
S)iii(;-l poisonip.y have been Ej;/ci3
reported
L)lrr-2 A rodcnticide USOS air:T..'A 0.5
alr-2 mg/oi3
S) irig-3
inh-3
L)irr-l LD5Q 54 Kg/kg USOS air:T.U 805
S)ing-2 ipr-mus ug/n3
inh-2 uses air:P;A 0.5
mg/n3
DO TDLo: 8 gn/kjr'
S)ing-2 . SOW TF.\:NEO
inh-2 ivg-ous
skn
abs-2
L)irr-2 Highly toxic
inh-2
S)U
L) ing-3
inii-3
S)lng-3
lnh-3
L) ing-3 ~
inh-3
S)lng-3
inh-3
t)ing-3 LDLo:85 r.;/kg
lnh-3 ivn-rr.us
S)inp,-3
inh-3
LD5a: 25 ng/kg
ivn-rbt
I.)slr-l
S)ing-l
lnh-1
Used .v; a hurbi- |;sos ,iir:lV,\ 1
cidc mg/ol
Used as a fungi-
ctdc
I.Hrr-2 USOS olr:TJA S
S)U pp:n
t.)U USOS .il r: TWA 0.1
SjlllR-l fPa
inh-3 ' IWOS utrrr/A 1
-------
I! IM?
rnoci:.ss, KASTC.JKOWICTIOH A:;U USK IWA
Source's ol I'rnci-ss
Ci'li'PQlinJ _ Kq.
Av»t>i'l ,-iU'J
W;l ;' 1 1- :;
W;isio
Tf. ;ii;m-nl
Ust-s
3)373
» 111
3)463
2)750
3)393
2)126
3)422.420
2)148
3)432
2)231
3)467
2)320
3)555,1134
2)328
3)559
3)559
2)328
3)559
2)16
3)574
2)344
3)573
3)575
2)619
3)1116
2)645
3)18. 832
-------
iM'.I.K r.-.'i. (Cii.il liu.->l)
It en
No
20
:i
22
23
: 24
25
26
27
23
29
30
31
32
33
34
35
36
37
Compound
Foriiailn
Iron (scrap)
U-.-i.! r:i rluii.it c (h.irtl.O
Lead peroxide
Kagncsluc oxide (luce)
Manganese chloride
Kingaaese dioxide
Mercuric oxide
Nickel acetate
Raney nickel catalyst
Oleua(sulfuric acid)
Phosgene
Phosphoaolybdic acid
Phosphorus oxychloride
Phosphorus penCachloride
Phosphorus trichloride
Phosphocungscic acid.
6Odiura salt
Potassium carbonate
(anhydrous)
Potassium hydroxide
Chcra. Al«sir.
(VI.N)
l\MVi$.. HI
l^\j .\ -i'l1- !
001309600
001309484
007773015
(MM C2)
001313139
001344452
000373024
(3.V1 i 2
-SI-)
007440020
(MI)
007664939
(USQQ)
000075445
(GVG)
010025373
(P 0 GB)
010026133
(P C5)
007719122
(? C3)
~
0013037:6
001310583
-3
pkn
ah? -3
Dtrr-2
S)U
DU
S) ing-3
inh-3
DU
S)ins-3
inh-3
Dirv-2
alr-3
S)iaS-3
inh-3
skn
abs-3
-
DU
S)'J
DU
S)U
-
Dirr-2
S)U
Dirr-2
S)U
Dirr-2
S)U
I.)lrr-2
S)U
Dlrr-2
S)tnC-2
Dlrr-3
S)U
roxti-ol.-.-v TLV
IWi'S .Mr: :V\
.' >S i.i-./ 11: '.
i
USOS alr:T.:.\
230 ug/c,3
TCLo:-''OOni-;/r,i USOS air:TC,\
TFX:UNS ihl-hcn 10ng/tn3
LDLe:210og/!tE
SCU-DUS
LD5Q:121 os/kg
Ipc-mu3
Ltil.o:45 ng/kg
iv.i-rb t
Highly toxic USOS air:TVA
0.05 mg/n3
USOS air: TWA
3 mg/m3
TDl.o:15 ng/n3/ t-SOS alr:n-;A
91WI, inh-gpg I- ng/o3
TCLo:300 ug/m3 USOS air:TOA
TFX MIH , ihl-hcn 1 Kg/a3
. TCLo:350 ug/n3
TFX:?UT., ihl-hnn
TDLo:25 ppn/30K
TFX:ItlR, ihl-hra
LC50= 75 ppm/
30M, ihl-rat
'
Highly toxic
LCLo:120 pp3i USOS alr:TOA
ihl-nus, highly 1 og/n3
caustic
I.CI.o:600 ppm/ 101! USOS air:lVA
ihl-aus 0.5 ppm
USOS alr:TJA
3 mg/ni3
Strong caustic
IK OS air: IV A
2 ng/m3
^^±
~^F~
Iron ci
-------
Sources of Process
Compoitml No.
As'socintcd
{.'.-isles
W.iste
total
.'Jwi ion
3) 8J6
2H.77
2)677
3)861 . .
2)6S6
3)19. 630
2)690
3)885
2)690
3)885
3)19, 895, 900
2)790
3)954
2)790
2)1096
3)985
2)887
3)1021
2)924
3)1025, 816
2)897
3)1025, 816, 21
2)924
3)1027, 816, 21
2)924
3)1027
2)950
3)1042
2)951
3)1047, 21
-------
T.V.I.::
Icon Kami1 mid
So, For-.-.,),,
33 Potassium pertun&aiiatu
j') S..Jiur.i I.is-.ill 1 lv
40 Sodlun bronate
41 Sodlua chljrata
42 Sodiua hyposulCite
43 Sodlua nitrite
44 Sodlua thiosulfate
45 Stannous chloride
46 Strontium chloride
47 SulEaolc acid
48 Sulfur
49 Sulfur chloride
50 Sulfur taoaochloride
51 Sulfuryl chloride
52 Thionyl chloride
53 Zinc
54 Zinc chloride
Clii'm. Ah*! r.
Resist ry K,-.
O'1-N)
(.KA.. MN-lKi)
n.l7i, .I'm".
0077S9330
(NA E-02-Q)
007775099
(NA C-02-Q)
"
007632000
(XA S-O-Q)
007772998
(SN C2)
010476854
(.SR..C2)
005329146
(2SWQ)
007704349
(S)
010025679
(S2 02)
010025679
007791255
(S 02 G2)
007719097
(S 0 C2)
007646857 .
(.ZK..G2)
. ..,v.|,..,v T,,,,!,. ,,,..
UllQ. n:.;/ki; A^-iHr (
10'W orl-r.\l 1.) trr-3
H'B-3
lnli-3
Inli-'l
Ml,,,-.-
iuh-2
MU
S) ing-2
LUl.o:1500 Big/kg I.) lrr-1
orl-rat S) lng-2
inh-2
M ing-2
inh-2
S)lnp-2
lnh-2
85 orl-rat MU
S)ing-3
lnh-3
700 orl-rat Mirr-2
S) ing-2
inh-2
1500 ug/kg Mirr-2
orl-rat S)U
_
Mirr-3
ing-3
lnh-3
S)U
Mirr-3
lng-3
lnh-3
S)U
"
,. , |-.,ii.-
:ii: . ii I.-
Mir r-2
S) l:v.-3
lnli-3
I.)1.1
' inli-1
MU
s)i;
MU
ir.ii-l
Ml'
S)ing-.1
luh-3
MU
S)U
MU
S)U
Mirr-2
inh-2
S)U
Mlrr-2
inh-2
S)U
Tcixli-i)li»:v TI.V Cnrcliiov-r.iiL5
Used as nn
herbicide
.._
Most thiosulfstcs
have low toKicicy
USDS alr:TWA 3.2
ng/n3
LD5;):908 icg/kg
ior-mus
Very low .
LCLo:153 ppn/lM "SOS alr:WA 1 ppm _
ihl-Eus l!sos air:r«'A 6 °g/
o3.
LCLo:150 poa/lM USDS air:TWA 1 ppn
ihl-nus ' U50S air:WA 6 ng/
Corrosive -~
Very toxic material . ~
and constitutes
serious toxic
hazards
Not toxic unless
heated
Furces arc highly USOS alr:TWA 1 TDLo:17 mg/kp
toxic ng/m] TFX:NEO, par-ha
TCLo:i300 w.f
03/30M TFX-.PL'l.
!.ll.o:'l3 rai-./kg
Ivii-r.-tt
-------
Source:! of
Cor.ipomul
Process
No.
To 1 nl
2)8.'.6
3)1051
2)234
3)471
2)306
3)1105
3)1111, 1131
2)301
3)962. 1114
3)1120
2)1133
3)1124
2)1082
2)1083
3)1130
2)1096
3)1132
2)1096
3)1132, 21
2)1096
3)1132, 21
2)1098
3)1136
2)1126
3)1166
3)1252
2)1206
3)1251. 22
-------
APPENDIX C
KEY TO ABBREVIATIONS AND ACRONYMS USED
IN TABLES IN APPENDICES A AND B
-------
C-l
KEY TO ABBREVIATIONS AND ACRONYMS
abs - absorption(s)
agn - agent(s)
air - allergenic effect(s)
aqtx - aquatic toxicity
BCM - blood clotting mechanism effects
bdw - wild bird species
BLD - blood effect(s)
BPR - blood pressure effect(s)
brd - bird (domestic or lab)
C - continuous
cc - cubic centimeter
CL - ceiling concentration
CAR - carcinogenic effect(s) j
cat - cat )
chd - child
chem - chemicals
concen - concentration(s)
ckn - chicken
CNS - central nervous system effects
COR - corrosive effects
ctl - cattle
CRIT DOC - criteria document
CUM - cumulative effects
CVS - cardiovascular effects
D - day
del - duck
DDP - drug dependence effects
DEF - definition
dog - dog
EYE - eye effects
frg - frog
GIT - gastrointestinal tract effects
GLN - glandular effects
gm - gram
gpg - guinea pig
H - hour
ham - hamster
hmn - human
inc - including
I - intermittent
IARC - International Agency for
Research on Cancer
ial - intraaural
iat - intraarterial
ice - intracerebral
icv - intracervical
idr - intradermal
idu - intraduodenal
ihl - inhalation
imp - implant
ims - intramuscular
ind - industry, industrial
inf - infant
ing - ingestion
int - intermediate
ipc - intraplacental
ipl - intrapleural
ipr - intraperitoneal
irn - intrarenal
irr - irritant effects
isp - intraspinal
itr - intratracheal
ivg - intravaginal
ivn - intravenous
ingred - ingredient(s)
insec - insecticide(s)
inhib - inhibitor(s)
kg - kilogram (one thousand grams)
L - local
lacq - lacquer
LC5Q - lethal concentration 50 percent kill
LCLo - lox/est published lethal concentration
LDijQ - lethal 'dose 50 percent kill
LDLo - lowest published lethal dose
mam - mammal (species unspecified)
man - man
M - minute
mtrl - material(s)
muc - mucous
nr* - cubic meter
mfg - manufacturing
mfr - manufacturer
mg ' - milligram (one thousandth of a
gram; 10~3 gm)
mky - monkey
mmi - mucous membrane effects
msk - muscolo-skeletal effects
mth - mouth effects
mem - membrane
mus - mouse
MUT - mutagenic effects
-------
ABBREVIATIONS
(Continued)
0
NEO - neoplastic effects
ng - nanogram (one billionth of
a gram; 10~° gm)
ocu - ocular
orl - oral
org - organic
par - parenteral
photo - photography, photographic
pg - picogram (one trillionth ',-,
of a gram; 10~12 g^
pgn - pigeon
pig - pig
pk - peak concentration
PNS - peripheral nervous system effects
ppb - parts per billion (v/v)
pph - parts per hundred (v/v) (percent)
ppm - parts per million (v/v)
ppt - parts per trillion (v/v)
prep - preparation(s)
psy - psychotropic
pul - pulmonary system effects
pharm - Pharmaceuticals
qal - quail
rat - rat .
RBC - red blood cell effects
rbt - rabbit
rbr - rubber
rec - rectal
rec'd - recommended
C-2
U - unknown
ug - microgram (one millionth of a gram;
10-6 gm)
unk - unreported
uns - toxic effects unspecified in source
USDS - U.S. Occupational Health Standard
W - week
wbc - white blood cell effects
WLN - Wisswesser Line Number
wmn - woman
Y - year
* - indicates closely related derivative
of the Chem. Abst. Registry No.
shown, such as a salt, free acid,
free base or lake
scu - subcutaneous
skn - skin
skn abs - skin absorption
SKN - skin effects
sql - squirrel
syn - synthetic(s), synthesis
sup - super script
S - systemic effects
solv - solvent(s)
TCLo - lox^est published toxic concentration
TDLo - lowest published toxic dose
TER - teratogenic effects
TFX - toxic effects
TLV - threshold limit value
tox rev - toxicology review
trk - turkey
TWA - time weighted average
TXDS - qualifying toxic dose
-------
APPENDIX D
REFERENCES USED IN APPENDICES A AND B
-------
D-l
REFERENCES USED IN APPENDICES A AND B
(1) Industrial Process Profiles for Environmental Use, Volume 6, "Industrial
Organic Chemicals", EPA Contract 68-02-1320, Task No. 17, Monsanto
Research Corporation, Draft being edited by Radian Corportion, Austin,
Texas (1976).
(2) NIOSH Registry of Toxic Effects of Chemical Substances. 1975 Edition,
U. S. Government Printing Office.
(3) Dangerous Properties of Industrial Materials, Irving Sax, Reinhold,
4th Edition (1975).
(4) The Merck Index of Chemicals and Drugs, R. G. Stecher, Ed., 8th
Edition, Merck and Company, Inc., Rahway, New Jersey (1968).
(5) Code of the Federal Register. Title 29, Labor, Parts 1910-1919, pp 559-
563, U. S. Government Printing Office, July 1, 1975.
(6) Manual of Current Indicators, Chemical Economics Handbook, Stanford
Research Institute, Menlo Park, California (February, April, October,
1975).
(7) Kirk-Othmer Encyclopedia of Chemical Technology, A. Standen, Ed.,
2nd Edition, Interscience Publishers, John Wiley and Sons, Inc.,
New York, Vols. 1-22, Supplement and Index (1972).
(8) Suspected Carcinogens, Subfile of the NIOSH Registry of Toxic Effects
of Chemical Substances, 1975, U. S. Government Printing Office.
(9) Synthetic Organic Chemicals, United States Production and Sales,
1973, United States International Trade Commission Publication 728,
U. S. Government Printing Office.
(10) Ibid, Preliminary Figures, 1974.
(11) Chemical and Engineering News, June 7, 1976, pp 36-37.
(12) Garner, D. N., and Dzierlenga, S., Organic Chemical Producers Data Base
Program, Data Base Report Generator. EPA Contract No. 68-02-1319, Task
No. 51, Radian Corporation, August 6, 1976.
(13) Wilkins, G. E., End Use Patterns for Significant Organic Chemicals, EPA
Contract No. 68-02-1319, Task No. 61, Radian. Corpoation-, July 21, 1976.
(14) Environmental Safety & Health Information, ERDA, Issue No. 336, April 16,
1976, p 3.
-------
D-2
(15) Steadman, T. R., Industrial Process Profiles for Environmental Use,
Volume 7, "Organic Dyes and Pigments", EPA Contract No. 68-02-1323, Task
No. 26, Battelle-Coluobus, Draft being edited by B.adian Corporation,
Austin, Texas (1976).
-------
APPENDIX E
INDUSTRIAL ORGANIC CHEMICALS - POSSIBLE
ADDITIONS TO THE MASTER LIST
-------
E-l
TABLE E-l. RADIAN LIST OF COMrOUTOS TO BE ADDED TO
. THE LIST Or INDUSTRIAL OUCANIC CHEMICALS^"'
Radian
Number
Compound
125
185
190
235
290
785
905
950
951
965
995
1170
1215
1230
965
950
951
1021
1170
1200
1230'
1495
1530
1545
2091
2145
2165
2210
2261
2321
2455
2665
2756 .
2757
2930
3270
3349
3354
3355
3395
Acetyl chloride
Adiponitrilc
Alkyl naphthalenes (methyl)
p-Amtnophcnol(c'
Any 1 phenol
Caprolactacr
Chlorobenzotrlchloride (o, p)
o-Chloronicrobenzene
p-Chloronitrobenzene
Chlorosulfonlc acid
Chlorotrif luoror.e thane
Cyclooctadiene
m-Dichlorobenzene
1 , 2-Dlchloroe thane
ChlorosulConlc acid
o-Chloronitrobenzene
p-Chloronitrobenzene
Cresols, mixed
Cyclooctadiene
a-Dichlorobenzene
1,2-Dlchloroethylene
Dimethylhydrazine
Dimethyl tcrephthalate
2.4-Dlnitrophenol(£)
Glycerol dichlorohydrln
Hexachlorobenzene
Hexamechylenediamtne
p-Hydroxybenzoic acld^S)
Isobutylene 00
Isopentane
Mecanlltc acid^
Methyl cethacrylate
o-Nitroantline 0)
p-Nlcroanlline CO
Phonylanthranilic acid (1)
Tannlc acid (a)
Toluene
2,4-ToluenedlisocyanaCe
Toluene diisocyanate
1 , 1 , 1-Trichloroc thane
CV1
NC4CN
L65J C
ZR DQ
QR X5
T7MVTJ
GXCGR XC
VRJR EG
VNR DC
H S-03 G
GXFFF
L8U CLTJ *C *C
CR CC
G1U1G
H S-03 G
VSB. EG
WNR DO
QR X
L8U CUTJ *C *C
GR CG
G1UIC
ZN1&1
10VR DV01
WNR BQ ENW
Q1YC1G
G 6-R
Z6Z
QVR DQ
1YU1
2Y
ZR CSWQ
1UYV01
ZR BNW
ZR DNW
QVR BMR
1R
OCNR B ENCO
OCNR X XNCO
CXCC
(a) Radian Use of compounds added to OCPDB (reference 12) and
supplied to Battelle on 6/2/76.
(b) Wisusser Line Notation.
(c) Item No. 645 page B-53, Table B-2 (ODP-I).
(d) Compound ncanc to be ethylcne dlchlorldc: WI.H C1C1.
(e) See under Item No. 374, page A-101, Table A-l (IOC).
(f) Item Ho. 667. page B-55. Table B-2 (ODP-I).
(g) Item No. 18, page B-l, Table B-l (ODP-K).
(h) Itea No. 64, page A-15, Table A-l (IOC).
(1) Item No. 31S, page E-27, Table B-2 (ODl>-I).
(J) Itcn Mo. 97, page B-ll, Table B-2 (OnP-I).
(1) Item No. 333, page A-89, ToMo A-l (IOC).
(m) Itcn No. 30, pace B"5, Table B-l (ODP-R).
-------
E-2
TABLE E-2. INDUSTRIAL ORGANIC CHEMICALS NOT ON
THE IOC LIST OR ON TABLE E-l - FROM
A 1975 PETROCHEMICAL COMPILATION(a)
Compound Name _ . WLN
(Methyl acrylate) 10V1U1
(n-Propyl acrylate) 30V1U1
. , (2 -Ethyl hexyl acrylate) 4Y2&10V1U1
Isophthalonitrile NCR CCN
Lactic acid QYVQ .
(c\
Linear alkyl benzenes v ' ' -
DL-Methionine QVM2S1
Peracetic acid QOV1
Propylene carbonate T50VOTJ D
Tetrahydrofuran T50TJ
Xylylene diisocyanate OCNR X X XNCO
(a) IOC = Industrial Organic Chemicals. Compounds
are taken from Hydrocarbon Processing (1975
Petrochemical Handbook issue), 54. (11); 76 D -
76 VV & 97-98, November, 1975, published by
Gulf Publishing Co., Houston, Texas.
(b) Other acrylate esters may also be of suffi-
cient importance to consider adding. Ethyl
and n-butyl acrylates are already on the
IOC list.
(cj Higher alkyl benzenes other than those already
listed (toluene and ethyl benzene are on the
IOC list); also some branched alkyl benzenes
are commercial and should be added.
-------
E-3
TABLE E-3. 1973 U.S. TARIFF COMMISSION REPORT
COMPOUNDS NOT ELSEWHERE LISTED(a)
1973
Production,
Compound MM/lbO>)
Hexamethylenedianmonium 770.4
adipate (Nylon 66 salt)
Sorbitol . 158.0
Melamine 118.6
Sodium carboxymethyl cellulose 68.5
2,6-di-tert-Butyl-p-cresol 32.0
Triethylene glycol monomethyl ether 29.1
Triethylene glycol monoethylene ether 23.4
Dipropyl amine . 18.1
Butyl benzoate 12.9
Tetraethylene glycol 12.1
Lead naphthenate % 11.6
Dibutyl maleate 11.2
Hexyl alcohol 9.8
Benzoyl peroxide 8.8
Dioctyl maleate 7.7
Salicylaldehyde 4.8
Dimethylaminoethanol 4.2
Lauroyl chloride 4.2
di-tert-Butyl peroxide 2.4
tert-Butyl peroxy benzoate 2.4
Dodecenylsuccinic anhydride 1.6
tert-Butyl peroxy-2-ethyl hexoate 1.4
4,4'-Methylenebis (N,Nf-dimethyl 1.2
aniline) (Michler's Ketone)
tert-Butyl peroxy pivalate 1.0
Diethylenetriamine(c) -
Isopropyl ether (O
Triethylenetetramine(c)
(a) Compounds produced commercially at 1 million pounds
per year or greater.
(b) Millions of pounds/year (divide by 2,2 to obtain
millions of kilograms/year).
(c) Sales of substantially more than 1 MM Ib/year indicates
similar production levels.
-------
E-4
TABLE E-4. ADDITIONAL COMPOUNDS TO BE CONSIDERED
FOR INCLUSION IN IOC TABLE A-l(a)
Benzidine
tert-Butyl hydroperoxide
Caprolactone
Tris (2,3-DibroEiopropyl phosphate)
Dichloromethyl ether
Cyclohexanone oxime
Dimethyl acetamide
Dimethyl carbamoyl chloride(b)
Ethyleneimine .
Hexahydrophthalic anhydride
Hexamethyl phosphoric acid
triamide (HMPT)^b)
3-Hexanone
8-Hydroxystearic acid
Lauryl alcohol
Methyl-n-amyl ketone
Methylene diisocyanate (MDI)
(p, p'-diphenylraethane diisocyanate)
Nadic methyl anhydride
Paraformaldehyde
2-Pentanone
Piperidine
Stearic acid
Terephthalonitrile
Trimethylolpropane
s-Trioxane
Vinyl pyridines
(a) Randomly identified compounds that are now or have been commercially
produced.
(b) Recently identified as potent carcinogens (Chemical Week,
June 2, 1976, page 31).
-------
E-5
TABLE E-5. COMPOUNDS NOT ALREADY INCLUDED WHICH ARE
COVERED BY EFFLUENT LIMITATIONS GUIDELINES
.'DEVELOPMENT DOCUMENTS - ORGANIC CHEMICAL
INDUSTRY(a)
Acetin
(Glyceryl monoacetate)
n-Butyl propionate
Calcium citrate
Calcium oxalate
Calcium stearate(b)
Calcium tartrate
Chloral
(Trichloroacetic aldehyde)
Chloroprene
Citral
Citric acid
Coumarin
Dichloroethyl sulfide
(mustard gas)
Ethyl nitrite
Geraniol(b)
Hydrazine solutions^)
lonone'k)
Methyl ionone'b)
Methyl salicylate^^
Monosodium glutamate
Oxalic acid
Pentachlorophenol
Saccharin
Silicones
(Chlorosilanes)
Sodium citrate
Sodium pentachlorophenate
Tartaric acid
Terpineol
Thioglycolic acid
Tricresyl phosphate
Tridecyl alcohol
Triphenyl phosphate
Vanillin
(a) Compounds not already included in IOC Table A-l or pre-
ceeding Tables 2-5.
(b) Compounds on the effluent guidelines priority list, i.e,
recommended standards published in EPA-440/1-74-0099,
April 1974 and EPA-440/1-75/045, November 1975.
-------
E-6
TABLE E-6. ORGANIC CHEMICALS IN IPPEU-IOC BUT WITH NO
PROCESS NUMBER - POSSIBLE ADDITIONS.TO THE
IOC LIST(a)
Aniline sulfate
o-Benzoylbenzoic acid
Bis(Chloroisopropyl) ether
Cobalt toluate
Cresol ether
Diallyl ether
Diamyl sulfide
2,4-Dimethyl-l-l,3-dioxane
Ethyl formate
Ethyl phenanthrene
Furfural
Glycidaldehyde
Hexane -
Isobutane
Methane
Methyl bromide
Methyl iodide
Naphthalene sodium sulfonate
(c)
o-Nitroanisole
Oxalic acid
Pentachloroethane
Phenanthrene
cx-Phenylethyl alcohol
Sodium ethoxide
Sodium glycolate
Sodium stearate
Stilbene
Terphenyl
2,4,6-Trichlorophenol
Trinitrophenol (Picric acid)
(a) Thirty-four organic chemicals are listed which appear in
Volume 6 reference (1) IPPEU-IOC (Draft), but which do
not have process number assignments. These compounds
should be considered for inclusion in the catalog as
primary entrants and for addition to the list of compounds
on which toxicity and process data are being assembled.
(b) Item No. 397, page B-33, Table B-2 (ODP-I).
(c) Item No. 123, page B-13, Table B-2 (OdP-I).
-------
APPENDIX F
INDUSTRIAL ORGANIC CHEMICALS - EXTRACTION
TABLES BASED ON TOXICITY AND PRODUCTION
VOLUME DATA IN TABLE A-l
-------
F-l
TABLE F-l. U.S. OCCUPATIONAL STANDARD (USDS) FOR CONCENTRATIONS IN AIR -
INDUSTRIAL ORGANIC CHEMICALS
[Listed Alphabetically According to Compound]
Compound
Number
3
7
8
9
11
14
15
17
19
20
24
26
30
32
39
48
49
54
56
57
60
. 61
65
66
67
68 '
69
70
71
72
73
79
Concentration ,
ppn
200
10
5
1000
40
0.1
0. 3 mg/m3 (skn) (b)
20 (skn)
2 (skn) J-
1
100
100
5 (skn)
0.5 mg/m (skn)
10
0.1
1
1
0.2
0.5
1000
500
-------
F-2
TABLE F-2 (Continued)
Compound
Number
248
249
255
258
259
260
263
265
267
270
273
275
276
277
279
280
281
282
284 .
286
287
288
Concentration ,
ppm
100
150
25
250
400
5
0.5
0.25
25
1 (skn)
200
200
10
2 (skn)
100, CL 200,"
PK 300/5M/3H
500
100
100 (skn)
500, CL 1000,
PK 20QO/5M/2H
200
100
25
Compound
Number
289
292
294
295
302
306
307
310
311
312
313
314
322
323
327
328
331
336
337
i to
338
347
350
Concentration ,
ppra.
100
CL 100
20 (skn)
10
1 (skn)
100
100
25
25
5 (skn)
5 (skn)
5 (skn)
10 mg/m3(c)
1000
100, CL 200,
PK 300/5M/3H
0.1
5 (skn)
0.1 mg/m (skn)
0.1
2
1000
200
Compound
Number
355
356
357
358
368
377
387
391
' 392
393
394
395
397
403
404
405
406
407
403
409
415G
Concentration ,
ppm
75
100
5
10(c>
100, CL 200,
PK 600/5M/3H
117/ug/tn3 (skn)
5 (skn)
10 (skn)
100, CL 200,
PK 300/5M/2H
1000
50
1000
25
10
1, CL 5
10(c)
100
100 (c)
100 (c)
* .
ioou;
5 (skn)
(a) Time weighted average (TW) unless indicated otherwise.
(b) (skn) indicates additional absorption through the skin is possible even when the concentration is
below the indicated standard.
(c) Not necessarily USOS.
-------
F-3
TABLE F-2. U.S. OCCUPATIONAL STANDARD (USDS) FOR CONCENTRATIONS IN AIR -
INDUSTRIAL ORGANIC CHEMICALS
(Listed According to Increasing Standard Concentrations]
Concentration(a) ,
ppm
0.1
0.1
0.l(O
0.1
0.1
0.2
0.2
0.25
0.5
0.5
0.5
1
1
1
1
1 (skn)(b>
1
1 (skn)
1 (skn)
1 (skn)
1
2 (skn)
2
2 (skn)
2
3
3
5
5 (skn)-
CL 5 (skn)
5
Compound
Number
14
48
85
328
337
7
56
265
8
57
263
20
49
54
164
168
179
238
270
302
404
19
114
277
338
188
227
8
30
70
73
Concentration^) ,
ppm
5 (skn)
5 (skn)
5 (skn)
5 (skn)
5 (skn)
5 (skn)
5 (skn)
5
5
5 (skn)
5 (skn)
5 (skn)
5 (skn)
5
5 (skn)
5' (skn)
10
10
10
10 (skn)
10 (skn)
10
. 10 (skn)
10
10
10 (skn)
10
10
10(0
10 (skn)
10
Compound
Nunber
111G
111
112
113
161
185
201
229
260
312
313
314
331
357
387
415G
7
39
79
86
126
160
163
192
202
243
276
295
358
391
403
Concentration (a) ,
Ppm
10(0
CL 15 (skn)
20 (skn)
20
20
20
20 (skn)
25
25 (skn)
25 (skn)
25 (c)
25
25
25
25
25
25
40
50
50
50
50
50
CL 50
50
50
50
50
75
75
100
Compound
Number .
405
137
17
84
203
228
294
143
216
217
242
255
267
288
310
311
397
11
101
116
123
124
129
133
204
211
221
394
94
134
26
-------
F-4
TABLE F-2. (Continued)
Concentration (a) ,
pptn
100
100
100
100
100 (skn)
100
100(c)
100 (skn)
100
100
100
100
100 (skn)
100
100
CL 100
100.
100
100
100
100
100
Compound
Number
24
62
69
72
176
193
205
214
245
248
279
281
282
287
289
292
306
307
327
356
368
392
Concentration^) ,
PDta
100
100(O
100 (O
100(c)
150
150
150
200
200
200
200
200
200 (skn)
200
200
200
200
250.
300
300
400
400
Compound
Number
406
407
408
409
68
71
249
3
65
66
67
194
213
273
275
286
350
258
122
125
222
259
Concentration^3) ,
pptn
500 (O
500
. 500
1,000
1,000
1,000
1,000
1,000
1,000
1,000
1,000
1,000
0.1 (skn)
0.117 (ska)
0.3 (skn)
0.5 (skn)
1 (skn)
1 (skn)
10
10<0
10(0
Compound
Number
61
280
284
9
60
135
187
196
323
347
393
395
336
377
' 15
32
167
163
178
232
322
(a) Time weighted average (TWA) unless indicated otherwise.
(b) (skn) indicates additional absorption through the skin is possible even when the
concentration is below the indicated standard.
(c) Not necessarily USOS.
-------
r-5
TABLE F-3. HUMAN TOXICITY DATA - INDUSTRIAL ORGANIC CHEMICALS
Compound
Numbar*3'
3
7
9
II
14
II
17
19
24
30
39
ti
44
54
56
60
62
64
79
ii
80
84
II
86
n
90
101
114
123
124
132
134
163
176
185
187
"
II
193
196
201
202
TDI.o TCLo
134 ppm
816 ppm/3M
500 ppm
12,000 ppm/4!l
1 ppa
-
16 ppm/20M
25 ppm
188 ppm/30H
.
-
210 ppn
6 mg/kg
16 ppm
4400 mg/m3
-'
25 ppa
200 ppm
10 ppm/3M
20 ppm/5M
580 mg/m3
50 mg/m3/7Y
20 ppm
44 mg/m3
10 ppm/lY
4.1 ppm
. ' . 100 ppm
50 ppm
25 (ig/m3
300 mg/kg
200 ppm
-
20 ppm
-
. .
50 mg/kg
1,000 ppra
13,000 ppm
-
200 ppm
LDLo LCLo TFX
IRR
IRR
EYE
CNS
IRR
153 ppm/ KM
PUL
IRR
IRR
350 mg/kg
20,000 ppm/5M - .
BLD
SKN
UNS
IRR
250,000 ppm/25M
- = PUT.
IRR
IRR
CNS
- IRR
4,000 ppm/30M
CNS
CNS
1,000 ppm
BID
SYS
IRR
MMI
IRR
EYE
UNS
CNS
470 ppra
EYE
2000 mg/kg
6000 mg/kg
. CIT
IRR
CNS
5000 mg/kg - . SKN
IRR
Adm(b)
thl
thl
ihl
thl
thl
thl
Ihl
thl
Ihl
orl
Ihl
thl
skn
Ihl
thl
Ihl
Ihl
Ihl
thl
thl
thl
Ihl
thl
ihl
Ihl
thl
thl
thl
Ihl
thl
ihl
orl
ihl
thl
thl
orl (chd)
orl
orl
sea
thl
skn
thl
-------
F-6
TABLK F-3. (Continued)
Compound
Number M.
204
It
205
211
216
227
it
243
II
259
tl
275
II
II
234
II
290
II
295
302
311
320
II
II
M
323
327
"
ti
328
ii
331
If
337
350
367
363
II
It
II
392
. II
395
404
TDLo
_
-
-
195 ppm/8H
-
-
-
-
-
-
-
-
-
100 mg/kg
-
-
7 rag/kg
70 mg/kg
-
200 mg/kg
15 ppra
14 mg/kg
14 mg/kg
71 mg/kg
14 mg/kg
-
-
-
-
-
-
14 mg/kg
-
25 ppm/30M
-
-
-
-
-
-
-
-
-
-
TCt.o
.
4,000 ppra/H
-
-
25 ppm
13. 8 ppm
-
-
-
400 ppm
300 ppm
-
-
500 ppm/m
500 ppm/8H
-
-
-
-
-
-
-
-
-
130,000 ppra
230 ppm
230 ppm/2H
600 ppm/lOH
45 ppm
-
-
-
-
-
-
-
600 ppm
376 ppra
20 mg/m3
160 ppm/33M
110 ppm/8U
4500 ppm
20 pptn
UM.O LCFxi
845 mg/kg
-
1500 mg/kg
-
-
36 mg/kg
-
750 us/kg
120 tcg/nVlH
2371 mg/kg
-
-
340 rag/kg
. -
-
-
-
-
100 tag/kg
-
-
- '
-
-
-
-
-
-
-
' -
483 ppm/lOM
-
140 mg/kg
.
5700 mg/kg
5000 mg/kg
10,000 ppra/30M
-
-
-
-
-
-
-
TFX
_
CMS
-
IRR
CNS
-
IRR
-
-
-
IRR
CNS
-
EYE
CNS
BIO
PSY
CNS
-
BLD
CNS
PSY
PSY
PSY
PSY
CIS
SYS
EYE
CMS
EYE
-
CIT
-
IRR
-
-
-
IRR
OiS
CLN
CNS
-
CMS
CVS
Adm
orl
thl
orl
Ihl
Ihl
orl
Ihl
orl
Iht
orl
thl
thl
orl
orl
thl
. thl
orl
orl
orl
orl
thl
orl
tvn
1ms
rec
Ihl
thl
thl
thl
thl
thl
ort
orl
Ihl
orl
unk
thl
thl
- thl
thl
Ihl
thl
Ihl
thl
(b)
(ran)
*
(chd)
(wmn)
(«rm)
(wmn)
(a) Item number of compound tn Industrial Organic Chemicals Cable.
(b) Method of administration (sec Itst of abbreviations and acronyms).
-------
F-7
TABLE F-4. CARCINOGENS OR SUSPECTED CARCINOGENS - INDUSTRIAL ORGANIC CHEMICALS
Compound
1,
5
21
35
36
n
39
48
54
It
86
ii
n
n
it
"
101
106
117
"
121
II
123
134
137 .
141
tt
144
156
tl
II
164
n
176
178
185
II
187
II
TDLo TCLo
600 gm/kg/VI
455 gm/kg/52W
8400 mg/ks/84DI
16 goi/kg/24UI
90 gWkg/90DC
72 gm/kg/90D
1232 mg/kg/52W
2000 mg/kg/28WC
50 mg/kg
2100 mg/kg/51WI
4800 rag/kg/88DI
133 gm/kg/25HI
3680 mg/kg/30WI
159 gm/kg/25MI
159 gm/kg/20WI
120 mg/kg/88DI
18 gm/kg/120DI
38 gm/kg/12WI
304 Big/kg
10 gm/kg/76WI - .
22 gm/kg/73WI
18 mg/kg/73W
Suspected carctnogen-hmn
142 mg/kg/I
33 gm/kg/79WIC
2400 mg/kg/48MC
2400 mg/kg/44M
Suspected carcinogen o£ Che bladder-hem
1900 mg/kg/SlWI
800 Bg/kg/49WI
. 50 mg/kg
17 mg/o>3/18«I
50 mg/kg
416 gm/kg/57WC
Recognized carctnogen-hntn . -
19 mg/kg
720 mg/kg/18WI
2770 gm/kS/79WI
548 gm/kg/78WI
TFX
NEO
CAR
NEO
NEO
NEO
NEO
CAR
NEO
NEO
NEO
CAR
NEO
CAR
CAR
CAR
CAR
CAR
NEO
NEO'
NEO
NEO
KEO
-
CAR .
CAR
NEO
CAR
-
CAR
NEO
CAR
CAR
NEO
CAR-
-
NEO
NEO
NEO
CAR
Ad.-Ant^lOO
skn-mua
orl-rat
orl-rat
orl-rat
orl-rat
orl-rat
skn-mus
skn-mus
scu-rat
scu-rat
orl-mus
acu-rat
orl-ham
scu-rat
roc-mus
orl-mus
orl-mus
skn-mus
thl-mus
Scu-mus
orl-rat
unk-rat
-
scu-ous
orl-mus
scu-mus
scu-mus
-
orl-rat
scu-rat
scu-rat
thl-rat
scu-rat
orl-rat
-
Ihl-mu3
SCU-Q1U9
orl-mus
rec-mus
-------
F-8
TABLE F-4. (Continued)
Compound
205
227
It
241
265
285
It
295
320
328
329
330
331
344
356
363
367
377
382
386
387
392
404
ii
ii
410
411
412
413
414
ii
TDLo
4 gm/kg
1300 mg/kg/65WI
Suspected carcinogen of the lung
144 gm/kg/72WI
610 mg/kg/61W
80 mg/kg
1410 mg/kg ' '
3500 mg/kg/98DI
12 gra/kg/W
-
Recognized carcinogen-hum
Recognized carclnogen-hmn
4000 mg/kg/2CWI
420 gm/kg/Y
Carcinogen, experimental
8500 mg/kg/19MI
2600 mg/kg/65H
86 mg/kg/28DI
280 mg/kg/35H
6.6 mg/kg/19HI
8200 mg/kg/24MI
351 gm/kg/78«I
-
.
Carcinogen of the liver
5600 mg/kg/28WI
5600 mg/kg/28HI
5600 mg/kg/Z8WI
5600 mg/kg/28MI
4000 mg/kg/l2(WI
64,000/mg/kg/2CHI
TCLo TFX
NEO
NEO
.
NEO
CAR
CAR
NEO
NEO
NEO
15 mg/m3/63WI CAR ,
-
-
CAR
CAR
-
NEO
" CAR
CAR
NEO
NEO
NEO
CAR
250 ppm/4H/260DI CAR
250 ppo/35MI CAR
-
CAR
CAR
CAR
CAR
NEO
NEO
Adn.An(mal(b)
skn-mus
scu-rat
-
scu-rat
scu-rat
orl-rat
scu-rat
scu-rat
skn-mua
Ihl-rat
-
-
skn-mus '
Ivg-mus
-
scu-rat
scu-rat
scu-mus
scu-rat
orl-rat
orl-rat
orl-raus
Ihl-rat
Ihl-mus
-
skn-mus
skn-mus
skn-mus
sknrmus
skn-rous
skn-mus
(a) Item number of compound In Industrial Organic Chemicals Cable.
(b) Method oE administration and animal (see list of abbreviations and acronyms).
-------
.TABLE F-5. TERATOGENS AND MUTAGENS
Item
No.
Compound
Mutagen
Teratogen
Carcinogen
IOC
156
diethyl sulfate
TDL0:85 mg/kg
(15 D preg),
TFX:TER, ivn-rat
potent
carcinogen
orl or scu
IOC
164
IOC
166
IOC
178
dimethyl sulfate
dimethyl sulfoxide
diphenylamine
TDL0:20 mg/kg
(15 D preg),
TFX:TER, ivn-rat
TDL0:5 gm/kg
(6-12 D preg),
TFXrTER, orl-rat
TDL0:8 gm/kg
(6-12 D preg)
TFXrTER, ipr-rat
TDL0:50 mg/kg
(8 D preg)
TFX:TER, ivn-ham
TDL0:7500 mg/kg
(17-22 D preg)
TFX:TER, orl-rat
potent
carcinogen
ihl or scu
recognized
carcinogen
-------
TABLE F-5. (Continued)
Item
No.
IOC
221
IOC
228
IOC
406
IOC-ADD
7
IOC-ADD
17
IOC-ADD
29
(a)
DPD
177
(b)
Compound
ethylene oxide
formamide
vinyl toluene
2,6-di-tert
butyl-p-cresol
Chloroprene
N,N-dimethyl
acetamide
CI 16185 Acid
Red 27
Mutagen
TDL0:3Q mg/m3
TFXrMUT, ihl-man
Tcratogen
TDL0:6 gm/kg
(11-160 D preg)
TFXrTER, ipr-rat
TCL0:29 mg/m3/13WI
TFX:TER
ihl-gpg
TDL0:5500 mg/kg
(preg)
TFXtTER, orl-rat
TDL0:39 mg/m3/4 H/48D
TFX:MUT., ihl-rat
TDLQ:600 mg/kg
(preg)
TFX:TER, ipr-rat
LDL0:1500 y/kg
(preg)
TFX:TER, orl-rat
Carcinogen
I
M
O
yes
orl-rat
-------
TABLE F-5. (Continued)
Item
No.
Compound
Mutagen
Teratogen
Carcinogen
DPD
280
DPD
316
CI 22120 Direct
Red 28
CI 23850 Direct
Blue 14
TDL0:80 mg/kg/
(8 D preg)
TFX:TER, unk-rat
TDLQ:25 mg/kg/
(8 D preg)
TFX:TER, scu-mus
potent
carcinogen
scu-rat
(a) IOC-ADD are industrial organic chemicals-addendum (cf Table A-3, Appendix A)
(b) Dye and pigment dye (cf Table B-3).
-------
F-12
TABLE F-6. ORAL TOXICITY (LD50, ORAL-RAT) VERSUS PRODUCTION
VOLUME, WASTE AND CARCINOGEN DATA - IOC
Rating
Order
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
IOC
Item
Num-
ber (a)
1 to 5C
10
166
14
51 to
137
89
364
328
185
17
201
101 to
112
48
203
15
175
72
375
113
354
111
270
173
251
414
12
90
114
290
LD50, Carcin- .
ing/kg ogen(b)
\ \ " /
17
20 T
46
100
75 +
76
76
83 +
90 ' +
93
95
300
121
130 +
140
170
177
180
200
207
220
242
250
268
280
296 +
300
300
300
300
1973 Production^), Waste(d)
MM kg (MM pounds) W A
245 (540) - 1969 +
28 (62) - 1974 +
29.1 (64.2) - 1969 . +
81.7 (180) +
614.8 (1354.2) ' +
11/2 (24.7)
150.3 (331.1) +
18.2 (40)
508.5 (1120)
+
+
+
__
1.0 (2.2)
+
-------
F-13
TABLE F-6. (Continued)
Rating
Order
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
IOC
Item
Num- . LD50, Carcin-
ber^3-) mg/kg ogen'k)
301 to 500
358
394
244
221
16
285
309
141
71
117
297
192
225
291
384
331
346
30
164
411
397
416
27
121
138
70
107
134
412
501 to 700
165
143
159
105
391
22
49
413
132
301
320
320
330 M
340
347 +
350
373 +
380
382 +
400
400
400
400
400
414 +
419 .
440
440 +,T
444 +
460
467
470
485 +
490
500
500
500 +
500 +
535
540
560
570
580
600
600
608 +
648
1973 Production (c), Waste(d)
MM kg (MM pounds) W A
11.8 (26) - 1970 +
8.1 (17.9) +
1890 (4167)
59.7 (131.6) +
91 (200)
205.6 (453)
25.2 (55.5) - 1972 +
. +
1019 (2241)
38.8 (85.5)
207.8 (457.6) +
+
.
58.1 (128.0) +
28.5 (62.7)
__
5 (11.1) - 1972 +
+
193.0 (425.1) - 1974 +
-------
F-14
TABLE F-6. (Continued)
IOC
Item
Rating Num-
Order ber^a)
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
501 to 700
106
204
160
701 to
174
264
142
126
73
390
202
70
6
101
227
260
191
418
91
156
41
312
357
360
387
356
415
307
386
115
1001 to
294
321
31
314
306
267
LD50, Carcin-
mg/kg ogen'b)
(Cont.)
670 +
680
698
1000
707
708
710
710
735
756
760
790
800
800 +
800 +
820
830
840
880
880 +, T
890
891
891
891
900 +
930 +
933
940
974 +
1,000
1500
1,050
1,070
1,072
1,072
1,100
1,120
1973 Production^0) ,
MM kg (MM pounds)
4210 (9292.7)
55.2 (121.5)
__
48.3 (106.2)
1.82 (4)
30 (66) - 1974
. 235.5 (518.6)
1.8 (4.0)
115 (252.8)
2918 (6424.1)
.125.1 (275.5)
3.4 (7.4) - 1968
18.9 (41.5)
797 (1753) .
__
'
Waste(d)
W A
__
+
__
'
+
+
-t-
+
+
+ +
+
+
___
-------
F-15
TABLE F-6. (Continued)
Rating
Order
IOC
Item
Num-
ber (a)
LD50,
mg/kg
Carcin- 1973 Production^ ,
ogent") MM kg (MM pounds)
Waste (d)
W A
1001 to 1500 (Cont.)
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
172
229
51
54
219
417
263
37
245
33
348
288
111G
211
215
254
79
1,122
1,210
1,230
1,231
1,260
1,297
1,300
1,300
1,300
1,400
1,400
1,410
1,454
1,480
1,480
1,480
1,500
1501 to 2000
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
349
102
372
124
316
53
86
8
295
340
350
355
3
304
235
1,510
1,540
1,540
1,620
1,620
1,700
1,770
1,780
1,780
1,860
1,870
1,900
1,930
1,960
2,000
+
+
2001 to 3000
134 123 2,060
135 103 2,078
136 289 2,080
24.2 (53.1)
5.9 (12.9)
36.5 (80.4) - 1972
0.9 (2.0)
f
15.9 (35)
26.1 (57.5)
62.4 (137.8)
22.4 (49.3)
27.4 (60.4)
289.7 (638.2)
49 (108)
476 (1047)
758.2 (1670)
272.6 (600.5)
42.1 (92.6)
657.2 (1447.6) - 1972
325.5 (716.9) - 1968
70.3 (154.8)
-------
F-16
TABLE F-6. (Continued)
Rating
Order
IOC
Item
Nuia-
LD50,
mg/kg
Carcin-
ogen^)
1973 Production^, Waste^
MM kg (MM pounds) W A
2001 to 3000 (Cont.)
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
188
. 284
184
313
4
255
299
216
248
80
298
42
250
308
378
94
116
224
403
81
177
23
213
274
283
2,100
. 2,136
2,140
2,144
2,180
2,330
2,420
2,460
2,460
2,490
2,590
2,710
2,810
2,828
2,860
2,910
2,910
2,920
2,920
2,940
3,000
3,000
3,000
3,000
3,000
162
163
164
165
166
167
168
169
170
171
172
173
174
3001 to 4000
24
25
44
223
410
55
78
207
56
7
179
217
286
3,030
3,030
3,040
3,200
3,200
3,249
3,250
3,250
3,280
3,310
3,370
3,390
3,400
40.2 (88.4)
236 (520.2)
39.1 (86.2)
60.2 (132.8)
216 (477)
180.5 (397.5)
1210 (2665)
- 683 (1503)
86.5 (190.3)
5.4 (12)
36.8 (81) - 1974
182.5 (402.3)
2.3 (5) - 1971
1104 (2429)
246 (540.7)
-------
F-17
TABLE F-6. (Continued)
Rating
Order
IOC
Item
Num-
ber^)
LD50,
mg/kg
Carcin-
ogen
(b)
c
1973 Productionv. Waste
MM kg (MM pounds) W
(d)
3001 to 4000 (Cont.)
175
176
177
178
179
180
181
182
183
184
185
186
69
193
361
242
34
68
11
39
145
190
129
88
3,500
3,500
3,530
3,696
2,700
3,730
3,800
2,800
3,900
3,980
4,000
4,000
>4000 .
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207 .
208
338
362
127
163
208
2
35
128
220
292
152
392
368
407
409
189
259
68
367
268
5
293
4,020
4,100
4,170
4,200
4,390
4,570
4,620
4,720
4,890
4,900
4,920
4,920
5,000
5,000
5,000
5,600
5,800
6,480
7,400
9,400
30,000
30,000
2580 (5688)
10.9 (23.9)
38 (128)
378.9 (834.5)
465 (1023)
5.4 (11.8)
23.8 (52.5)
205 (451.7)
2716 (5975)
2627 (5780) - 1974
1057 (2326)
100.5 (221.5)
833 (1835)
24.9 (54.9) - 1967
2716 (5975)
228 (501.8)
-f-
+
-------
F-18
TABLE F-6. (Continued)
Footnotes.
(a) Item number of compound in Industrial Organic Chemicals Table A-l.
(b) A plus (+) indicates that this compound is a known or suspected
carcinogen; M indicates mutagen; and T indicates teratogen.
(c) A dash () indicates no production data available. A number
follox^ed by a year indicates no 1973 data, but instead data for
another year.
(d) Quantitative waste data on specific compounds available. W =
effluent data, and A = air or emissions data.
-------
F-19
TABLE F-7. ORAL TOXICITY (LD 50, ANIMAL OTHER THAN RAT VALUES ^ 500 mg/kg)
VERSUS PRODUCTION VOLUME, WASTE AND CARCINOGEN DATA - IOC
Rating
No.
1
2
3
4
5
6
7
8
9
-10
11
12
13
14
15
16
IOC
Item No. (a
167
388
265
340
41
383
19
25
160
91
227
331
368
314
202
413
LD 50
) mg/kg Carcinogen (b)
42 bdw
42 bdw
60 mus +
65 mus -
75 bdw
75 bdw
96 mus
200 mus
240 rbt
316 mus
256 mus
260 gpg +
300 mus +
316 mus
330 mus
470
477 mus +
1973 Production, Waste^
MM kg W A
.
128 + +
:
55
2918
1019
30 . +
+
(a) Item number of compound in Table A-l. Four compounds (19, 167, 265, 383) do not
have any oral-rat data. All the other compounds listed have LD 50, oral-rat
values > 500 mg/kg.
(b) A plus C+l indicates the compound is a known or suspected carcinogen.
(c) Quantitative waste data on specific compounds in effluent (W) and air or emissions
(A) are available for marked (+) compounds).
-------
F-20
TABLE F-8. ORAL TOXICITY (LDLQ, ALL ANIMALS) VERSUS PRODUCTION VOLUME,
WASTE AND CARCINOGEN DATA - IOC
Rating
Order
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
IOC
Item No. (a)
377
168
161
83
20
334
235
336
350
131
259
310
277
387
275
236
271
311
382
412
LDL0,
mg/kg Carcinogen
17 rat +
29 cat
50 hmn
50 rat
64 rat
80 rat
100 rat
140 mus
157 cat +
192 mus '
250 rbt
280 rbt
300 cat +
340 hmn
500 rbt
500 mus
500 rat
500 rat +
500 rat +
1973 Production Waste
MM kg W A
160 +
7
395 ' +
42 . +
17
3210 +
204
88 +
(a) Item number of compound in Industrial Organic Chemicals Table A-l. Only the 20
compounds that do not have LD 50, orl-rat data ^ 500 mg/kg are .shown. There
are a total of 32 compounds that do not have LD 50 orl-rat requested.
(b) A plus (+) indicates this compound is a known or suspected carinogen.
(c) A minus (-) indicates no production data.
(d) Quantitative waste data on specific compounds in effluent (W) and air emissions
(A) available.
(e) Special note-human data.
-------
F-21
TABLE F-9. INHALATION LC50 DATA VERSUS CARCINOGEN,
PRODUCTION, AND EMISSION
Rating
Order vft
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
IOC
Item No.
377
101
337
119
243
117
270
17
10
211
275
221
51
189
55
356
351
61
143
202
7
216
114
116
39
272
86
128
LC50,
ppm/H/animal Cc) Carcinogen^)
6/ /rat +
59/ /rbt . +
28/ /mus
75/0.5/rat
110/0. 5/mus
114/0. 5/gpg
1,087/lm/mgy
118/0. 5/rat
207/0. 5/gpg
169/0. 5/mus
220/4/rat
328/4/rat
36/4/raus
576/4/gpg
575/2/mus
700/7/mus
1,0007 /mky
1,462/4/rat ,.M
836/4/mus
960/4/dog
1,000/8/rat
1,0007 /rat
(200 mg/m3/ /mus)
1,740/4/mus +
2,310/4/rat
(658 nig/m3/ /rat
4,000/4/rat
4,000/8/rat .. - '
5,620/1/mus
(1,340 mg/kg/ /rbt)
(1,510 mg/m3/2/mus)
8,000/4/rat
10,000/17/rat +
(2,000 mg/m3/24/rat)
9,526/8/mus +
(4,000/mg/m3/ /mus)
1973
Production,
mm kg
160
115
331
-
138
-
(
615
245
62
3210
1890
6
100
-
797
1.6^)
-
5
30
1104
39
-
1210 ,
5130
.-
476
-
Emission
Data(e)
+
+
-
-
-
-
+
f
+
+
+
-
-
+
-
+
-
-
+
-
+
+
-
_
-
-
-------
F-22
TABLE F-7. (Continued)
(a) All compounds with inhalation lethal concentration, 50 percent test
animal population data from Table A-l.
(b) Approximate ordinal ranking based on inhalation toxicity (i.e, in order of
lowest lethal concentrations); different exposure times/animals makes
ranking only approximate.
(c) Parts per million/hours/animal. Blank spaces indicated data not available.
Data in parentheses are milligrams/cubic meter.
(d) Carcinogen or neoplasm (M = mutagen).
(e) Specific compound quantitative emission data in Table A-l in Ib/ton. No
quantitative effluent data are available on these compounds.
(f) 1974.
-------
F-23
TABLE F-10. TOXICITY DATA = 500 MG/KG OR ^ 1000 PPM
NOT INCLUDED IN TABLES F-6 THROUGH F-9 -
ANY ANIMAL OR ADMINISTRATION ROUTE
IOC
Item
No.
3
4
8
17
20
21
46
49
57
83
85
86
88
90
105
126
127
133
137
138
140
152
156
164
176
180
185
192
201
203
204
211
227
229
230
263
267
268
273
LDLo:
LD50:
LCLo:
LCLo:
LCLo:
LDLo:
LDLo:
LDLo:
LD50:
LCLo:
LD50:
LCLo:
LDLo:
LDLo:
LD50:
LD50:
LCLo:
LCLo:
LCLo:
LCLo:
LCLo:
LD50:
LD50:
LCLo:
LCLo :
LCLo:
LD50:
LCLo:
LD50:
LCLo:
LDLo:
LCLo:
LCLo:
LCLo:
LD50:
LD50:
LCLo:
LCLo :
LD50 :
LCLo:
Toxic Dose, Carcin-
mg/kg(a) ogen
500 ipr-rat
140 skn-rat
1000 ppm/4H, ihl-rat
500 ppm/4H, ihl-rat .
290/8H, ihl-rat
500 ipr-mus +
180 scu-mus
125 ppm/4H, ihl-rat
150 ipr-mus
400 ppm, ihl-rat
298 scu-mus
1000 ppm, ihl-hmn +
4 ipr-mus -
310 scu-cat
355 ipr-rat
200 ipr-rat
500 ppm/2H, ihl-rat
707 ppm/7H, ihl-rat
1000 ppm/45M, ihl-rat +
125 ppm/4H, ihl-rat
260 ppm, ihl-rat
150 skn-rbt
340 ivn-rat +
250 ppm/4H, ihl-rat
75 ppm/17M, ihl-mus +
470 ppm, ihl-hmn +
500 ipr-mus
250 ppm/4H, ihl-rat +
39.0 dkn-rbt
32 ppm/4H, ihl-rat
500 scu-rat
1000 ppm/4H, ihl-rat
500 ppm/4H, ihl-rat
250 ppm/4H, ihl-rat +
145 ivn-mus
200 ipr-mus
53 ppm/100 M, ihl-rat
1000 ppm/4H, ihl-rat
49 ipr-mus
67 mg/m3/56M, ihl-cat . -
1973
Production
MM kg
657
-
758
615
395 (b)
-
-
145
-
-
476
-
-
-
-
-
34
-
-
-
-
-
-
7
229
25
-
4210
62
2918
-
-
-
-
31
Waste
W A
+
-
-
-
-
-
-
-
+
-
-
-
-
-
-
-
-
,. -
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
+
-
+
+
+
-
+
-
+
-
-
-
-
-
+
+
+
+
-
-
-
-
-
-
-
+
+
-
+
+
+
-
+
-
-
(continued)
-------
F-24
TABLE F-10. (Continued)
IOC
Item
No.
284
294
295
299
302
308
311
327
331
354
361
375
378
386
391
392
394
397
403
475
Toxic Dose,
mg/kg(a>
LDLo: 200 ivn-dog
LD50: 500 skn-rbt
LD50: 150 ipr-mus
LDLo: 100 scu-mus
LDLo: 150 ivn-dog
LDLo: 100 ivn-dog
LCLo: 714 ppin/5H, ihl-cat
LDLo: 85 ivn-dog
LD50: 250 ipr-rat
LD50: 344 scu-mus
.LCLo: 500 ppm/4H, ihl-rat
LD50: 335 ivn-mus
LCLo: 1000 ppm/4H, ihl-rat
LCLo: 275 ppm/8H, ihl-gpg
LD50: 150 ipr-mus
LD50: 227 scu-mus
LCLo: 500 ppm/8H, ihl-rat
LDLo: 150 ivn-dog
LCLo: 1000 ppm/4H, ihl-rat
LCLo: 1000 ppm/4H, ihl-rat
LDLo: 500 ipr-rat
LDLo: 225 ivn-dog
1973
Carcin- Production
ogen MM kg
236
- -
+ 164
- -
140
-
-
321
+ 1019
- -
-
-
+ -
170(°)
+ 205
-
13
683
77
Waste
W A
- +
-
_
- -
_
+
-
-
+ +
-
+
_
-
- +
+
-
+
_
- +
(a)
(b)
(c)
Chemical administration units
.otherwise indicated in table;
ihl-animal .
1970.
1971.
in mg chemical/kg body weight unless
inhalation data given in -
ppm/time,
-------
F-I5
TABLE F-ll TOTAL PRODUCTION - INDUSTRIAL ORGANIC CHEMICALS
[LISTliD ALPllAiiETICALLY ACCORDING TO COMPOUND]
Compound
Number (")
3
6
7
8
9
10
11
12
13
14
15
16
17
18
20
23
24
30
33
39
44 .
47
51
53
54
55
57
60
62C
62
65
66
68
70
71
72
73
SO
84
86
87
89
.
94
101
Tocnl Produce Inn . ni'lllons of k\* (tntlltons of pounds)
Earlier Yn.irs 1972 1973
657.2 (1447.6)
1.8 (4.0
1014.9 (2235.4) 1104 (2429)
758.2 (1670)
904 (1989)
245.2 (540) - - _
- 68 (150)"
1.0 (2.2)
- - -
18.2 (40)
59.7 (131.6)
614.8 (1354.2)
711 (1567)
395 (870) -1970
- .
5.4 (12)
207.8 (457.6)
0.9 (2.0)
5130 (11,300)
- ' -
- 0.33 (0.74)
5.9 (12.9)
. _ .
36.5 (80.4)
2.3 (5) - 1971 35.5 (77.9)
145.1 (319.7)
-
10,074 (22,190)-
_ -
36.8 (81.0)
24.9 (54.9) -
1967
58.1 (128.0)
235.5 (518.6)
- - 205.6 (453)
508.5 (1120)
- 1-82 (4)
216 (477)
352.9 (777.4)
476 (1047)
378.9 (834.5)
29.1 (64.2) -
1969
180.5 (397.5)
115 (252.8)
197-',
_
-
1033.7 (2530)
800 (1760)
900 (1980)
-
_
1.2 (2.7)
230.2 (507)
27.7 (61)
-
197S
.
-
954 (2100)
651 (1520)
723 (1591)
.
.
.
-
-
431 (948) inclesters
642 (1412)
754 (1630)
' '
6.1 (13.5)
-
25Q (551)
-
4587 (10,091)
36.8. (81)
0.43 (0..95)
6.3 (13.9)
0.64 (1.42)
-
-
171.1 (376.8)
1674 (3682)
-
494 (1087)
_
-
254 (558)
-
-
-
-
-
-
-
-
134.0 (295.2)
552 (1215)
668 (1470)
-
-
.
187 (412)
-
3482 ,(7660)
- .
-
-
-
-
1202 (2*45)
-
_
-
155 (341)
-
-
-
-
-
' -
-
-
-
-
-------
T-26
TABLE F-ll. (Continued)
Compound.
Number'1'1' Earlier Vears
104
112
111C Cresylic
116
122
123 325.5 (7f6.9) -
1963
124
125
133
134
135
142
143
144
148
150
154
160
161
172G
176
173
181
185
187
188
189
191
192
193
195
196
199
202
203
204
205
206
211
213
216
221
222
223
227
229
230
,232
Total Production! million.1) of kg (millions of pounds)
1972 1973
.
11.2 (24.7
35.9 (79.0)
1210 (2665)
965 (2123)
-
289.7 (638.2)
965 (2123)
63.4 (139.7) 30 (66)
- 28.5 (62.7)
222 (488.8)
' - 48.3 (106.2)
5 (11.1)
122.0 (268.7)
11.5 (25.3)
12.6 (27.8)
6.2 (13.7)
55.2 (121.5)
7.1 (15.7)
-
7.4 (15.2)
15.7 (34.7)
24.2 (53.3)
229 (503)
890 (1961.8)
141 (310)
100.5 (221.5)
125.1 (275.5)
25.2 (55.5)
2580 (5638)
2.9 (6.5)
299.7 (660.1)
-
-
150.3 (331.1)
4210 (9292.7)
1485 (3277.6)
2.8 (6.1)
62.4 (137.8)
86.5 (190.3)
39.1 (86.2)
1890 (4167)
32.8 (72.4)
182.5 (402.3)
2913 (6424.1)
24.2 (53.1)
24.3 (53.5)
94.4 (208)
(synthetic
1974
63.6 (140)
-
-
1325 (2910)
1063.7 (2343)
-
-
1068 (2352)
-
-
233.3 (515)
50.4 (111)
-
140.5 (329.1)
-
-
'
-
'
217.6 (522.8)
-
-
-
-
862.5 (1900)
89.1 (196)
'
139 (305)
-
-
10,859 (23,890)
30 (66)
-
3496.3 (7701)
1518 (3340)
-
72.2 (159.0)
-
1765 (3383)
27.2 (60)
2654.0 (5345.3)
-
19.1 (42)
161.8 (356.3)
1975
-
-
-
895 (1970)
-
-
-
805 (1773)
. -
-
-
-
-
-
.
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2700 (5940)
1727 (3800)
-
-
-
-
-
-
.
-
-
-
-
-------
F-27
TABLE ₯-11. (Continued)
Compound,
Number1"'
236
239
241
242
243
244
248
249
250
253
234
256
257
259
265
268
269
275
276
279
284
285
286
' 288
289
292
293
295
299
302
316
322
327
331
334C
337
338
343
344
346
347
Total Production, millions of kc (millions of pounds)
Earlier Ye;irs
204 (450) - 1967
-
-
'
-
-
-
-
-
-
55.4 (112) -
1967
-
151.8 (334.3) -
1971
-
-
30.9 (68) - 1968
-
-
-
-
-
-
'
-
-
-
-
-
10.8 (23.8) -
1955
-
'
'
-
29.1 (64) -
1971
-
-
104.4 (230 -
1967
. -
-
21,802 (48.022) -
1971
1972 1973
45.7 (100.7)
45.7 (100.7)
10.9 (23.9)
138.1 (304.3)
8.1 (17.9)
60.2 (132.8)
5.3 (11.75)
-
79.2 (174.3)
22.4 (49.3)
-
_
833 (1835)
128 (282)
-
321 (706)
3210 (7064.4)
16.8 (37.0)
247 (544.1)
236 (520.2)
-
246 (540.7)
15.9 (35)
70.3 (154.8)
23.8 (52.5)
228 (501.8)
164 (360)
_
140.1 (308.7)
49 (108)
46.8 (103.2)
321 (706)
1019 (2241)
-
330.6 (728.2)
465 (1023)
-
25.8 (56.9)
38.8 (85.5)
-
. 1974 1975
_
_ _
'* -.
_. _
^ ^
_ _
_ _
173.6 (381.9)
81.7 (180)
_
53.6 (118)
869.1 (1914.4)
132 .(290)
_ ' _
_
3126 (6878)
24.9 (54.7)
207.3 (456.7)
264.1 (581.7)
91 (200)
230 (506)
-
94 (207)
26 (57)
-
-
* » »
-
-
57 (125) 45.2 (99.6)
334 (734) 306 (674)
1045 (2298) 783 (1722)
_ _
394 (867)
444 (977) 322 (709)
84 (184)
44 (97)
-
.. - _
349
27.4 (60.4)
40 (87)
-------
F-28
TABLE F-U. (Continued)
Co-pound. ToC.il Production, millions of kg (millions of oonnds)
Number1"1' Earlier Years 1972
350 - -
351 ' - 7.6 (15.7)
353
356
357 3l4 (7.4) -
1968
358 11.8 (26) -
1970
360 6.2 (13.6) -
' 1969
362
363 29.5 (64.9) -
1970
365 - -
368 -
374 (TPA)
374 (DMT)
377 - -
382
390 -
391 170.1 (374.6) -
1971
392
393
396
397
398 -
401 -
402
403
404 - . -
405 -
407G
408
409 -
1973
42.1 (92.6)
0.20 (0.44)
4493 (9884)
797 (1753)
-
-
18.9 (41.5)
%
5.4 (11.8)
31.1 (63.5)
17.5 (38.6)
2716 (5975)
-
'
160.4 (353.3)
87.6 (193)
13 (28)
-
205 (451.7)
152 (334)
44.8 (98.5)
-
51.3 (113.1)
13.1 (28.9)
3305 (7271)
683 (1503)
2432 (5351)
-
-
485 (1068)
1057 (2326)
1974
44 (26)
1.6 (3.6)
4761 (10,475)
798 (1756)
-
.
20 (44)
-
!
-
2708 (5956)
1936 J4260)
1483 (3262)
211 (464)
-
-
193.0 (425.1)
176 (388)
156.2 (344)
49 (108)
13 (29)
50 (110)
-
3447 (7583)
638 (1403)
2555 (5621)
77.2 (170)
2627 (5780)
480 (1056)
1230 (2707)
1975
_
-
3454 (7593)
692 (1523)
-
-
-
-
-
-
1999 (4393) .
2114 (4650)
-
-
-
-
-
-
-
-"
-
-
3359 (7390)
515 (1136)
1907 (4196)
-
2309 (5080)
303 (679)
1102 (2425)
(a) Item number of compound in Industrial Organic Chemicals table.
-------
F-29
TABLE F-12. TOTAL PRODUCTION - INDUSTRIAL ORGANIC CHEMICALS
[LISTED ACCORDING TO INCREASING PRODUCTION FOR 1973]
Total Production,
KM kg (KM pounds)
0.20 (0.44)
0.33 (0.74)
0.9 (2.0)
1.0 (2.2)
1.8 (4.0)
1.82 (4.0)
2.8 (6.1)
2.9 (6.5)
5.35 (11.8)
5.45 (12.0)
5.9 (12.9)
6.2 (13.7)
7.1 (15.7)
7.4 (16.2)
8.1 (17.9)
10.9 (23.9)
11.2 (24.7)
11.5 (25.3)
12.6 (27.8)
13.1 (28.9)
15.7 (34.7)
15.9 (35)
16.8 (37.0)
17.5 (38.6)
18.2 (40)
18.9 (41.5)
22.4 (49.3)
23.8 (52.5)
24.1 (53.1)
24.2 (53.3)
24.3 (53.5)
.25.8 (56.9)
26.1 (57.5)
'27.4 (60.4)
28.5 (62.7)
Compound
Number (a)
351
47
33
12
6
73
206
195
362
24
51
154
161
176
244
242
112
148
150
401
178
288
276
365
15
360
254
292
229
181
230
344
me
349
134
Total Production,
MM kt- (MM pounds)
30 (66)
31.1 (68.5)
32.8 (72.4)
36.8 (81.0)
38.8 (85.5)
39.1 (86.2)
40.2 (88.4)
42.1 (92.6)
44.8 (98.5)
45.7 (100.7)
45.7 (100.7)
46.8 (103.2)
48.3 (106.2)
49 (108)
51.3 (113.1)
55.2 (121.5)
58.1 (128)
59.7 (131.6)
60,2 (132.8)
62.4 '(137.8)
70.3 (154.8)
79.2 (174.3)
81.7 (180)
86.5 (190.3)
87.6 (193)
94.4 (208)
(synthetic only)
100.5 (221.5)
115 (252.8)
122.0 (268.7)
125.1 (275.5)
127.8 (281.8)
138.1 (304.3)
140.1 (308.7)
145.1 (319.7)
Compound
Nunbe r ( a '
133
363
222
67
346
216
188
350
396
239
241
322
142
316
398
160
70
16
248
211
289
253
185
213
382
232
189
101
144
191
265
243
302
57
-------
F-30
TABLE F-12. (Continued)
Total Production,
KM kg (MM pounds)
150.3 (331.1)
152 (334)
160.4 (353.3)
180.5 (397.5)
182.5 (402.3)
205 (451.7)
205.6 (453)
207.8 (457.6)
216 (477)
222 (488.8)
228 (501.8)
235.5 (518.6)
236 (520.2)
246 (540.7)
247 (544.1)
272.6 (600.5)
289.7 (638.2)
299.7 (660.1)
321 (706)
330.6 (728.2)
352.9 (777.4)
378.9 (834.5)
465 (1023)
476 (1047)
485 (1068)
508.5 (1120)
Compound
Number'3'
203
393
377
94
223
392
71
30
80
135
293
62
234
286
279
295
124
196
327
337
84
88
338
86
403
72
Total Production,
KM ks (KM Bounds)
614.3
683
711
758.2
797
833
890
904
965
965
1019
1057
1104
1210
1485
1890
2432
2580
2716
2918 '
3210
3305
4210
4493
5130
(1354.2)
(1503)
(1567)
(1670)
(1753)
(1335)
(1961.8)
(1989)
(2123)
(2123)
(2241)
(2326)
(2429)
(2665)
(3277.6)
(4167)
(5351)
(5683)
(5975)
(6424.1)
(7064.4)
(7271)
(9292.7)
(9884)
(11,300)
Compound
Number'3)
17
403
18
8
356
259
187
9
122
125
331
409 .
7
116
205
221
404
193
368
227
275
402
204
353
36
(a) Item number of compound in Industrial Organic Chemicals table.
-------
APPENDIX G
EPA PRIORITY LISTS
-------
G-l
TABLE C-l EFFLUENT GUIDELINES PRIORITY
LIST (IOC - Phase 1)(a)
IOC (b)
Compound ' Item Number
Acetaldehyde (3 processes) 3
Aceclc acid 7
Acetone (2 processes) "9
Acetylene 13
Acrylates 191, 68, 39ADD, 59ADD, 71ADD
Acrylic acid 16
Aniline 30
Bisphenol A 57
BTX Aromatics (2 processes) 39, 30DP-R, 407G
Butadiene (2 processes) 60
Caprolactan . 12ADD
Coal tar (2 processes)
p-Cresol 113
Cyclohexane 122
Dimethyl terephthalate 374
Ethyl benzene 193
Ethylene 199
Ethylene dichloride 204
Ethylene glycol 205
Formaldehyde 227
Methanol 275
Methyl amines . 276, 160, 401
Methyl methacrylate 64ADD
Oxo Chemicals 70, 80, 128, 223, 248,. 250, 254
Phenol 331
Propylene 353
Styrene 368
Terephthalic acid (3 processes) 374
Tetraethyl lead . 377
Vinyl chloride (2 processes) 404
Vinyl acetate 403
(a) Taken from reference 18.
(b) ADD in Table A-3, IOC Addendum; DP-R in Table B-l, OOP raw materials.
-------
G-2
TABLE G-2.
LIST (IOC - Phase 2)
EFFLUENT GUIDELINES PRIORITY
(a)
Compound
Item Number
Acrylonitrile
Sec-Butyl alcohol
Chlorinated methanes
Cresol, synthetic
Citric acid
Cumene
Dyes and dye intermediates
Hexamethylene diamine
Hexamethylene tetramine
Isobutylene
Isopropanol
.Maleic anhydride
Methyl ethyl ketone
Monosodium glutamate
Pentaerythritol
Perchloroethylene
Propylene oxide
Plasticizers
p -Xy lene
17
71
279, 284, 101, 86
111G
116
ODP
4 3 ADD
241
64
259
265
286
322
327
356
409
(a) Taken from Reference 18.
(b) 43ADD found in Table A-3, IOC Addendum.
-------
TABLE G-3. WATER QUALITY PLANNING AND STANDARDS CONSENT DECREE LIST
(a)
Compound
Appendix Item Numbers
IOC DP-I
(b)
Acenaphthane
Acroleln
Acrylonitrile
Benzene
Benzidine
Carbon tetrachloride
Chlorinated benzenes
Chlorobenzene
Trichlorobenzenes (Isomers)
(1,2,4-Trichlorobenzene)
Chlorinated ethanes
1,2-Dichloroethane
1,1,1-Trichloroethane
Hexachloroethane
Chloroalkyl ethers
Chloromethyl ether (Dichloromethyl ether)
Chloroethyl ether (Dichloroethyl ether)
Mixed ethers
Chlorinated naphthalene
1-Chloronaphthalene
2-Chloronaphthalene
Chlorinated phenols
(b)
Trichlorophenols (isomers)
Chlorinated cresols (isomers)
Chloroform
2-Chlorophenol'
Cyanides
Hydrogen cyanide
Acetone cyanohydrin (2-Methyl lactonitrile)
1
14
17
39
5ADD
86
(General class - other than dichlorobenzenes)
94DP
390G
390
(General class -. specified compounds follow)
204
8 3 ADD
238
(General class - specific compounds follow)
137
(General class - specific compounds follow)
102
103
(General class - other than those listed elsewhere,
includes trichlorophenols and chlorinated cresols)
8 4 ADD
101
106DP
243
10
o
i
-------
TABLE G-3. (Continued)
Compound
Appendix Item Numbers
IOC DP-I
(b)
Dichlorobenzenes (General class)
1,2-Dichlorobenzene
1,3-Dichlorobenzene
1,4-Dichlorobcnzene
Dichlorobenzidine
Dichloroethylenes (General class)
l,l-Dichloroethylene(c)
1,2-Dichloroethylene
2, 4-Dichlorophenol
Dichloropropane (General class)
1,2-Dichloropropane
Dichloropropene (General class)
1,2-Dichloropropene
2,4-Dimethylphenol(d)
Dinitrotoluene (Isomers below)
2,3-Dinitrotoluene
2,4-Dinitrotoluene
2,5-Dinitrotoluene
2,6-Dinitrotoluene
Diphenylhydrazine
Ethyl benzene
Fluoranthene
Haloethers
Chlorophenylphenyl ether
Bromophenylphenyl ether
Bis(dichloroisopropyl) ether
Polychlorinated diphenyl ether (isomers)
Halomethanes
Methylene chloride
Methyl chloride
133G
133DP
5ADD 281
134DP
434
405
136
27ADD
355
140
410
172G
172
173
174
175
83ADD
193
(General class - other than those listed elsewhere)
o
(General class - other than those listed elsewhere)
284
279
-------
TABLE G-31 (Continued)
Compound
Appendix Item Number
IOC DP-I
Methyl bromide
Bromoform
Dichlorobromomethane
Trichlorofluoromethane
Dichlorodifluoromethane
Hexachlorobutadiene .
Hexachlorocyclohexane
Hexachlorocyclopentadiene
Naphthalene
Nitrobenzene
2,4-Dinitrophenol
Pentachlorophenol
Phenol
Tetrachloroethylene
Toluene
Trichloroethylene
Vinyl chloride
61 ADD
393
255
295DP
(General - specific compounds follow)
3 3 ADD
331DP
o
i
Ul
392
404
(a) Inorganics and organic insecticides and herbicides deleted from published decree as not
pertinent. The chemicals listed are to be covered by the Effluent Guidelines Standards
for Best Available Technology Economically Achievable by June 30, 1983.
(b) ADD refers to compounds in Table A-3, IOC Addendum, DP-I to compounds in Table B-2.
(c) Table B-l.
-------
G-6
TABLE G-4. POTENTIALLY SIGNIFICANT AIR
TOXICANTS FROM THE OFFICE OF
AIR QUALITY PLANNING AND
STANDARDS (AQPS)
Compound
IOC Number
Acetaldehyde 3
Acetonitrile 11
Acrolein 14
Acrylonitrile 17Dp(a)
Allyl chloride . 20
Aniline 30DP
Benzene 39
Carbon tetrachloride 86
Chloroform 101
Chloroprene
Di(2-ethyl hexyl phthalate)
Dimethylatnine 160DP
Dioxane 176
Ethylene dibromide 203
Ethylene oxide 221DP
Formaldehyde 227DP
Hydrogen cyanide 243
Maleic anhydride 265
Nitrobenzene 302DP
Perchloroethylene 327
Trichloroethylene 392 -
Vinylidine chloride 405
(a) Table B-l.
(b) Table A-3, IOC Addendum.
-------
G-7
TABLE G-5. THIS STUDY "PRIORITY" LIST IOC DISTRIBUTION
ON EPA PRIORITY LISTS(a,b)
IOC
Item
No.
1
3
10
14
16
17
20
30
39
70
71
86
101
111
113
133
134
135
137
140
160
173
175
176
203
204
205
221
227
241
243
259
265
275
284
295
302
327
331
Effluerit
Guidelines
Priority
List - Phase 1
(Table G-l)
__
X
X
X
2X
X
X
X
X
3X
2X
3X
Effluent
Guidelines
Priority
List - Phase 2
(Table G-2)
3X
X
3X
2X
X
X
X
2X
X
X
*
WQPS
Consent
Decree
List
(Table G-3)
X
2X
3X
2X
3X
2X
X
X
X
3X'
X
X
X
X
.
X
X
X
3X
OAQPS
Priority
List
(Table G-4)
.
X
X
3X
2X
X
2X
3X
2X
X
2X
2X
3X
3X
X
2X
~*~ .
(continued)
-------
G-8
TABLE G-5. (Continued)
Effluent Effluent WQPS
Guidelines Guidelines Consent OAQPS
IOC Priority Priority Decree Priority
Item List - Phase 1 List - Phase 2 List . List
No. (Table G-l) (Table G-2) (Table G-3) (Table G-4)
356 2X
368 X
377 X
403 X
404 -- X
405 -- 2X
410 X
(a) Seven (7) "priority" lists from the present study are included
(Tables F-4 through F-10).
(b) X means commonality of entrants on one table from the group
Table F-4 through Table F-10, 2X and 3X indicate occurrence
on two or three of these tables.
-------
G-9
TABLE G-6. LIST OF POTENTIALLY HAZARDOUS WASTE MATERIALS
. IOC Item No.
3
7
8DP
9DP
10
11
1ADD
13
Acridine
14
16
17DP
19
20
24 (Banana Oil)
25 (Fusel Oil)
30
Anthracenes
39
42 ADD
41DP
44DP
54DP
60
61
62DP
64
67
70
73DP
Butyl mercaptan
78DP
80
84
86
User's (b)
SIC No.
»»
20,38
20,26,36
38
__
20
34
19
22,26,31
22,30
19
20,22,39
. *
22,38
30,38
__
38
30
29
__
22,26
30
Production
MM, Ibs
1,652
1,770
1,675
1,589
970
150
<10
468
- <10
<10
150
1,037
<10
<10
<10
64
372
100
8,000
800
<10
55
88
3,054
2,160
404
1,630
127
63
11
<10
<10
<10 .
1,640
935
-------
G-10
TABLE G-6. (Continued)
User's Production
IOC Item No. SIC No. MM, Ibs
337 447
Chloral hydrate <10
Chloroacetophenone 29 <10
94DP 700
101 -- 239
18ADD 154
111G 20,33 245
114 20 <10
116 1,500
128
122 280
123DP 716
124DP 704
126DP 30 72
128 162
Dibutyl phthalate 29
133DP 75
134DP 72
137
284 418
355 -- 86
140
142DP 92
143DP 29,30 7
222 -- . 102
176
28ADD .
158 32
Diisobutylketone
160DP 74
181 45
37ADD . 533
185 20 120
186
187DP 20 320
-------
G-ll
TABLE G-6. (Continued)
IOC Item No.
188DP
189
191
192DP
193
196DP
199
203DP
Ethylene cyanohydrin
202
Dibromoe thane
204
205DP
213
212
221DP
38ADD
223
Ethyl mercaptan
286
Ethyl phthalate
2-Ethyl-3-propylacrolein
227DP
229DP
40ADD
Furfural alcohol
Heptane
43ADD
Hexane
243
244DP
249
248DP
255
257
259
258
260DP
53ADD
267
User's Production
SIC No. MM, Ibs
22,29 265
159
22,26,31 167
20 16
4,700
600
15,600
29
65
__ ' __
6,700
2,400
3,671"
22,26,34 1.5
440
20,22,39,73 4,312 (37%)
22,31 40
380
22
244
34
232
33,34 410
34 12
34
30 300
2,000
44
20
22 12
-------
G-12
TABLE G-6. (Continued)
IOC Item No.
275
273
59ADD
276DP
61ADD ' -
279
Methyl chloroformate
287
289
Methyl mercaptan
64ADD
277
294DP
295DP
96 and 980DP-I^C)
302DP (c\
278, 279, and 2800DP-IV '
306
307
309
310
311
313
65ADD
6 7 ADD
Pentachlorophenol
323
327
331DP
374DP
347
348
349
n-Propylacetate
350
User's
SIC No.
29
31
30
30
26
29
29
30,34
31,34
«»
30
'
29
34
__
19,34
22,31
22,24,26
38
22
29
30,32
20
:
Production
MM, Ibs
9,245
9
120 (30%)
21
432
430
21
. 700
10
515
100
50
__
18
23
47
706
1,680
760
7,200
40
21
68
-------
G-13
TABLE G-6. (Continued)
IOC Item No.
351
353
293
356
355
357DP
48
360DP
365DP
Sodium oxalate
368
375DP
377
81ADD
Tetramethyllead
82ADD
387
39 OOP
391
392
396
397
399
88ADD
401
85ADD .-
403
404
.4Q7DP
(a) Reference 17.
(b) End use patterns for the
User's
SIC No.
29
.'
20
30
34
30
26
"
29
22
22,33,34
__
32
29
_
29,35
30,44
Production
MM, Ibs
0.2
7,240
450
1,121
7
__
44
.
4,400
371
76
_*.
9
15
340
239
77
80
20
48
799
4,040
chemical, classified by stand-
ard industrial classification numbers,
(c) Table B-2, organic dyes
(d) Table B-l, organic dyes
and pigments -
and pigments -
as shown below.
intermediates.
other materials.
-------
C-14
TABLE C-7. SPILLS LIST OF POTENTIALLY HAZARDOUS SUBSTANCES
(a)
Compound
Acetaldehyde
Acetic acid
Acetic anhydride
Acetone cyanohydrln
Acetyl bromide
Acetyl chloride
Ac role in
Acrylonitrlle
Adiponitrile
Allyl alcohol
Allyl chloride
Benzene
Benzole acid
Benzonitrile
Benzoyl chloride
Benzyl chloride
Butyl acetate
Buty lamina
Butyric acid
Carbon disulfide
Chlorobenzene
Chloroform
Chlorosulfonic acid
Cresol
Hydrogen cyanide
Cyclohexane
2,6-Dichlorobenzonltrile
Die thy lamina
Dimethylamine
Dinltrobenzene
Dlnitrophenol
Dodecylbenzenesulfonic acid
Ethyl benzene
Ethylenediamine
Ethylenediaminotetraacetic acid (EDTA)
Formaldehyde
Formic acid
Fumaric acid
Furfural
EPA Toxicological
Criteria(o)
1
1
1
2
1
1
1, 2
1
2
1
1
1
1
1, 3
1
1
1, 2
. 1
1
1
1
1
1
1
1. 2
1
1
1
1
1
1, 2
1
1
1
1
1
1
1
1
Appendix Table Item Kumbers(c)
IOC DP-R DP-I
3
7
8
10
-
1ADD
14
17
2ADD
19
20
39
44DP
46
50DP
54DP
65 W)
66 (O
67 (g)
73«>
74(0
7S(S)
81
84
94DP
101
8ADD
111(0
113 (k)
243
122
-
143DP
167G
167(0
168(10
169(J)
-
-
193
202
'
227DP
229DP
230
.
.
.
.
-
-
-
-
-
- '
-
-
-
-
-
-
-
-
-
.
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
'
**
-
.
.
-
-
-
-
-
-
-
-
-
-
-
. -
-
-
-
-
-
-
-
-
-
.
-
-
-
-
-
-
291
-
-
-
-
-
-
.-
-
.
-------
G-15
TABLE C-7. (Continued)
Comoound
Isoprene
Maleic acid
Maleic anhydride
Methyl mercaptan
Methyl methacrylate
Monoethylamine (e thylamine)
Monome thylamine
Naphthalene
Kaphthenic acid
Nitrobenzene
Nitrophenol
Parafortnaldehyde (Paraform)
Pentachlorophenol
Phenol
Phosgene
Polychlorir.ated biphenyls (PCB)
Propionic acid
Propionic anhydride
Propyl alcohol
Qu in o line
Resorcinol
Styrene
Tetraethyl lead
'Tetraethylpyropho.sphate
Toluene
Trichlorophenol
Trie thylamine
Tr iiae thylamine
Vinyl acetate
Xylene
Xylenol
.
EPA Toxicolocical
Criteria^)
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1.
1, 2
1
1
1
1
1
1
1
Appendix
IOC
257
264
265
-
64ADD
192DP
276DP
295DP
-
303G
303(J)
30400
305(D
308G
308(J)
309 00
67ADD
-
331DP
337
-
349
-
350
-
358DP
368
377
-
-
84ADD
397
401
403
407DP
410G
4110")
412
413(0)
414(p)
Table Item
DP-R
-
-
-
23
-
-
-
-
-
-
-
-
'
-
-
-
-
-
-
-
-
-
-
-
30
-
-
-
-
-
-
Numbers'0'
DP-I
.
-
-
-
-
-
- '
-
-
-
-
-
-
. -
-
-
-
-
-
-
-
' -
-
-
-
-
-
-
-
.
-
-
See footnotes on following page.
-------
C-16
TABLE C-7. (Continued)
(a) Reference 6.
(b) Toxlcologlcal criteria.
1 = aquatic animal toxlcity
2 = oral mammalian toxlcity
3 = dermal manmaltan toxicity.
(c) Item numbers in master Tables A-l, B-l, and B-2.
IOC = Industrial Organic Chemicals
DP-R = Dye and Pigment Raw Material
DP-I *> Dye and Pigment Intermediate
G = commercial isomer mixture.
(d) 11-
(f) sec-
(g) tert-
(h) Cresylic acid
(i) m-
(j) o-
(k) p-
U) 2,4-
(m) 2,5-
(n) 3,4- .
(o) 3,5-
(p) 2,6-
-------
APPENDIX H
ORGANIC DYES AND PIGMENTS - EXTRACTION
TABLES BASED ON TOXICITY AND PRODUCTION
VOLUME DATA IN TABLES B-l THROUGH B-3
-------
H-l
TABLE H-l. U. S. OCCUPATIONAL STANDARD (USOS)
FOR CONCENTRATIONS IN AIR -
ORGANIC DYES AND PIGMENTS
[LISTED ALPHABETICALLY ACCORDING TO COMPOUND]
Compound ^a'
DP-RO 3
DP-RO 9
DP-RO 11
DP-RO 15
DP-RO 20
DP-RO 23
DP-RO 25
DP-RO 30
DP-RI 5
DP-RI 6
DP-RI 7
Ditto
DP-RI 16
DP-RI 18
DP-RI 19
DP-RI 21
DP-RI 22
DP-RI 23
DP-RI 26
DP-RI 27
DP-RI 28
DP-D 447
Concentration^^
0.5 mg/m3
50 ppm
10 ppm
1 ppm
25 ppm
0.5 ppm
1 mg/ra3
100 ppm
10.2 mg/m3
0.5 mg/m3
806 g,g/m3
0.5 mg/m3
1 mg/m3
5 ppm
0.1 ppm
258 u-g/m3
230 jig/m3
10 mg/m3
0.05 mg/m3
3 mg/m3
1 mg/m3
1 ppm
Compound'3'
DP-RI 29
DP-RI 33
DP-RI 34
DP-RI 37
DP-RI 45
DP-RI 49
DP-RI 50
DP-RI 54
DP-I 83
DP-I 93
DP-I 98
DP-I 104
DP-I 105
DP-I 280
DP-I 291
DP-I 674
DP-I 683
DP-I 743
DP-I 744
DP-I 745
Concentration'"'
1 mg/m3
1 mg/m3
0.5 ppm
2 mg/m3
3.2 mg/m3
1 ppm
1 ppm
1 mg/m3
(c)
5 ppm (skn)
2 ppm (skn)
1 ppm (skn)
0.1 ppm (skn) .
0.1 ppm (skn)
1 mg/m3 (skn)
1 mg/m3 (skn)
100 u-g/m3 (skn)
0.1 mg/m3
5 ppm
5 ppm
5 ppm
(a) Item number of compound in Organic Dyes and Pigments table.
DP-RO: Dyes and Pigments - organic raw material;
DP-RI: Dyes and Pigments - inorganic raw material;
DP-I: Dyes and Pigments - intermediate;
DP-D: Dyes and Pigments - dye.
(b) Time weighted average (TWA).
(c) (skn) indicates additional absorption through the skin is possible even
when the concentration is below the indicated standard.
-------
II-2
TABLE H-Z. HUMAN TOXICITY DATA - ORGANIC DYES AND PIGMENTS
Compound
Number^3'
DP-RO 20
DP-RI 19
DP-RI 23
DP-RI 29
Ditto
DP-RI 30
DP-RI 54
DP-I 44
DP-I 63
DP-I 76
DP-I 279
DP-I 482
DP-I 708
DP-D 447
LDLo TDLo TCLo
10 ppm
2000 mg/kg
400 mg/m3
800' u-g/m3
350 |j,g/m3
25 ppm/30M
4800 mg/m3/30M
1000 mg/kg
44 mg/m3
25 |j,g/m3
12 |j,g/m3
500 mg/kg
5100 u.g/ni3
40 mg/kg
TFX
CNS
-
UNS
MTH
PUL
IRR
PUL
CNS
BID
EYE
EYE
SKN
IRR
-
Adm(b)
ihl
orl
ihl
ihl
ihl
ihl
ihl
orl
ihl
ihl
ihl
skn
ihl
ivn
(a) Item number of compound in Organic Dyes and Pigments table.
DP-RO: Dyes and Pigments - organic raw material;
DI-RI: Dyes and Pigments - inorganic raw material;
DI-I: Dyes- and Pigments - intermediate;
DP-D: Dyes and Pigments - dye.
(b) Method of administration (see list of abbreviations and acronyms).
-------
H-3
TABLE H-3. CARCINOGENS AND SUSPECTED CARCINOGENS
ORGANIC DYES AND PIGMENTS
Compound ^a'
DP-RO 10
DP-RO 15
DP-RO 27
DP-RO 29
DP-RI 8
DP-RI 27
DP-RI 28
DP-RI 54
DP-I 84
DP-I 130
DP-I 131
DP-I 225
DP-I 226
DP-I 429
DP-I 434
DP-I 441
DP-I 459
DP-I 480
DP-I 633
DP-I 634
DP-I 635
DP-I 637
DP-I 743
DP-I 744
DP-I 745
DP-D 10
DP-D 14
Ditto
DP-D 30
DP-D 52
DP-D 61
DP-D 63
DP-D 126
DP-D 169
DP-D 177
DP-D 181
DP-D 316
DP-D 343
DP-D 559
DP-D 576
DP-D 577
DP-D 579
DP-D 580
DP-D 583
DP-D 608
DP-D 631
DP-D 648
DP-D 873
(a) Item number
DP-RO: Dyes
DP-RI: Dyes
DP-I: Dyes
DP-D: Dyes
TDLo
280 mg/kg/35W
400 mg/kg/5WI
10 gm/kg/3WI
18 gra/kg/2YC
8 gm/ks/50U
350 ng/kg/43WI
15 tag/kg/GUI
17 tng/kg
7300 mg/kg/lY
90 gm/kg/90DC
2740 mg/kg/GlWI
17 gm/kg/2YI
4 mg/kg
5300 mg/kg/35WC
26 gm/kg/50H
6.5 mg/kg/44WI
9000 mg/kg/30DI
37 gm/kg/61W
16 gm/kg/lYI
Bladder 'carcinogen - hum
31 gm/kg/YI, 25 mg/kg
dl gm/kg/YI
31 gm/kg/YI
Recognized carcinogen - hmn
Recognized carcinogen - hnn
Recognized carcinogen - hnn'
Recognized carcinogen - hmn
1600 mg/kg/2.3 YI
800 mg/kg/40D
11 gm/kg/12WC
158 gm/kg/56WC
56 gm/kg/52WC
6 gm/kg/52W
80 mg/kg
428 gm/kg/65WC
2750 mg/kg/28WI
172 gm/kg/26WC
524 gm/kg/74WC
825 mg/kg/65WI
512 mg/kg/53WI
40 gm/kg/87WC
6500 rag/kg/33WI
5925 mg/kg/48WI
600 mg/kg/43KC
17 gm/kg/2YI
1290 gm/kg/86WC
9400 mg/kg/2YI
270 gm/kg/30WI
7200 mg/kg/44WI
10 gm/kg/2YI
o£ compound in Organic Dyes and Pigments
and Pigments - organic raw material;
and Pigments - inorganic raw material;
and Pigments - intermediate;
and Pigments - dye.
TFX
NEO
CAR
NEO
NEO
NEO
CAR
NEO
NEO
NEO
NEO
.NEO
NEO
CAR
CAR
CAR
CAR
NEO
CAR
NEO
_
NEO
CAR
CAR
-
«
-
-
CAR
CAR
NEO
NEO
NEO
CAR
NEO
CAR
NEO
CAR
CAR
CAR
CAR
CAR
NEO
CAR
CAR
CAR
CAR
NEO
CAR
NEO
CAR
table.
Adm-Anir.:al(°>
scu-rat
ipr-mus
skn-mus
orl-rat
ivg-mus
ims-rat
scu-rat
par-ham
orl-rat
orl-rat
orl-rat
scu-rat
scu-rat
orl-rat
orl-rat
scu-rat
orl-rat
skn-nus
scu-rat
^
SCU-EIUS
orl-rat
orl-rat
-
-
-
skn-rat
orl-rat
orl-mus
orl-mus
orl-mus
scu-mus
imp-mus
orl-rat
scu-rat
orl-rat
orl-rat
scu-rat
scu-rat
orl-rat
scu-rat
scu-rat
orl-rat
scu-rat
orl-rat
scu-rat
scu-rat
scu-rat
scu-rat
t
(b) Method of administration and animal (see list of abbreviations and acronyms).
-------
H-4
TABLE H-4. ORAL TOXICITY (RAT) -
ORGANIC DYES AND PIG-
MENTS, RAW MATERIALS
Rating
Order
1
2
3
4
5
6
7
8
9
10
ODP
Item
Number (a)
29
15
7
3
22
11
2
9
18 M
30 <-c'
LD50,
mg/kg
20
60
75
115
148
698
1830
2060
3200
5000
Carcinogen
+
+
-
-
-
-
-
-
-
(a) Item number of compound in Organic
Dyes and Pigments Table B-l.
(b) A plus (+) indicates that this
compound is a known or suspected
carcinogen.
(c) Production volume 3100 (6658).
-------
H-5
TABLE H-5. ORAL TOXICITY (RAT) - ORGANIC DYES
AND PIGMENTS, INTERMEDIATES
Rating
Order
1
2
3
4
5
6
7
8
9
10
11
12
13
14 "
15
16
17
18
19
20
21
22
23
OOP
Item
Number ('
1 to
2
667
51 to
84
101 to
499
445
459
278
63
301 to
480
645
555
85
668
750
764
501 to
96
97
226
76
47
95
701 to
112
423
LD50, , v 1973 Production
l) mg/kg Carcinogen Volume, MM kg
5Q(c,d)
30 -
30 - 0.45
100
65 +
300(e>f) v
120 -
144
224 +
288 - - .
300
500
301 +
375
400
418 - 0.3
447
464
467 -
700
535 - -
535
620 +
648 - .
664
681 - 0.8
1000
704 - -
717
-------
H-6
TABLE H-5. (Continued)
Rating
Order
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
OOP
Item
Number (£
635
633
10
61
743
225
1001 to
277
105
77
748
1501 to
58
343
44
11
2001 to
466
20
613
427
669
471
3001 to
716
98
12
451
> 4000
380
LD50, , . 1973 Production
L) mg/kg Carcinogen Volume, MM kg
727 +
779 +
800 - 1.7
. 880 -
974 +
1000 +
1500
1070
1400
1500
1500
2000
1620
1640
1650 .
1830
3000
2230
2400
2420
2460
2828
2830
4000
3020
3249
3350
3360
4250
-------
H-7
TABLE H-5. (Continued)
(a) Item number of compound in Organic Dyes and Pigments
Table B-2.
(b) A plus (+) indicates that this compound is a known or
suspected carcinogen.
(c) LD50 value range.
(d) Item number 758 has LD50, oral-bdw = 3. Item No. 291,
Ibid = 42.
(e) Item numbers 64, 72, 81, and 390 have LD50, oral-bdw =
"100.
-------
H-8
TABLE H-6. ORAL TOXICITY (RAT) - ORGANIC
DYES AND PIGMENTS, DYES
Rating
Order
1
2
3
4
5
6
7
OOP
Item
Number ^a'
446
14
598
655
631
839
447
LD50,
mg/kg
535
800
1000
1895
2000
2000
3249
1973 Production
Volume, MM kg
_
-
155
-
~
(a) Item number of compound in Organic Dyes
and Pigments Table B-3.
-------
APPENDIX I
USSR MAXIMUM ALLOWABLE CONCENTRATIONS
QF HARMFUL. COMPOUNDS IN WORKING - AREA
AND INHABITED AREA ATMOSPHERES
-------
1-1
TABLE 1-1. COMPARISON' OF UNITED STATES AND USSR
OCCUPATIONAL STANDARDS
IOC
Number
3
7
8
9
11
13
14
15
17
19
20
24
30
33
39
48
49
56
57
60
61
62
67
68
69
71
72
73
79
84
85
86
94
101
111
112
113
111G
114
116
Comnound Name
Acetaldchyde
Acetic acid
Acetic anhydride
Acetone
Acetonitrile
Acetylene
Acrolein
Acrylamide
Acrylonitrile
Allyl alcohol
Allyl chloride
n-Amyl acetate
Aniline
o- and p-Anisidine
Benzene
p-Benzoquinone
Benzo trichloride
Biphenyl
Bisphenol A
Butadiene
Butane
n-Butanol
n-Butyl acetate
sec-Butyl acetate
tert-Butyl acetate
sec-Butyl alcohol
tert-Butyl alcohol
n-Butylamine
tert-Butyl toluene
Carbon disul£ide
Carbon tetrabromide
Carbon tetrachloride
Chlorobenzene
Chloroform
m-Crcsol
o-Cresol
p-Cresol
Cresylic acid
Crotonaldehyde
Cumene
USOS(a),
ppm
200
10
5
1000
40 .
20% may cause
headache in hrans;
40% may cause
collapse^)
0.1
-
20s (0
2s
1
100
5s
-
10(0
0.1
l(c)
0.2(O
0.5
1000
500(O
100
150
200
200
150
100
C 5s(O
10
20
0.l(O
10s
75
C 50
(10 reed by NIOSH)
5s
5s
5s
5s
2
50
m?,/M3
VSOS
360
25
20
2400
70
.
0.25
0.3s
45s
5s
3
525
19s
0.5s
- '
0.4
-
1(0
2.8
2200
-
300
710
950
950
450
300
C 15s
60
-
-
65s
350
240
22s
22s
22s
22s
6
245
MAC
5
5
-
200
-
-
0.7
-
0.5
2
-
100
Is
Is
5s
0.05
0.5 or
0.2
-
5
-
300
10
200
-
-
-
-
10
-
10
20s
50s
-
-
-
-
-
0.5
50
-------
1-2
TABLE 1-1. (Continued)
IOC
Number
122
123
124
125
126
129
133
134
135
136
137
143
160
161
163
164
167
168
176
. 179
185
187
188
189
192
193
194
196
201
202
203
204
205 '
211
213
214
216
217
221
222
227
228
229
ncno(a) m^/M3
Compound Name
Cyclohaxane
Cyclohexanol
Cyclohcxanone
Cyclohexene
Cyclohexy lamina
Diacetone alcohol
o-Dichlorobanzene
p-Dichlorobenzena
Dichlorod if luorome thane
1 , 2-Dich loroo thy lene
Dichloroethylether
Diethy lamina
Dime thy lamina
N,N-Dimethylaniline
N,N-Dimethylformamide
Dimethyl sulfate
m-Dinitrobenzene
p-Dinitrobenzene
p-Dioxane
Diphenyl oxide (phenyl ether)
Epichlorohydrin
Ethanol
Ethanolamine
Ethyl acetate
Ethylamine
Ethylbenzene
Ethyl bromide
Ethyl chloride
Ethylene chlorohydrin
1,2-Ethanedianiine
Ethylene dibromide
Ethylene dichloride
Ethylene glycol
Ethylene glycol monobutyl ether
Ethylene glycol monoethyl ether
Ethylone glycol monoethyl ether
acetate
Ethylene glycol monoethyl ether
Ethylene glycol monomethyl ether
acetate
Ethylene oxide
Ethyl ether
Formaldehyde
Formamide
Formic acid
pnm
300
50
50
300
10s (c)
50
C 50
75
1000
200
C 15s
25
10
5s
10s
Is
-
-
100s
1
5s
1000
3
400
10
100
200
1000
5s
10
C 20
50
. 100(c)
50s
200s
100s
25s
25s
50
400
3
20
5
usos
1050
200
200
1015
240
C 300
450
4950
790
C 90s
75
18
25s
30
. 5
Is
Is
360s
7
19s
1900
6
-
18
435
890
2600
16s
25
-
260(0
240
740
540
80
120
90
1200 '
-
-
9
MAC
-------
1-3
TABLE 1-1. (Continued)
IOC
Number
232
238
242
243
244
245
248
249
255
253
259
260
263
265
267
270
273
275
276
277
279
280
281
282
284
286
287
288
289
292
. 294
295
302
306
307
310
311
312
313
314
322
323
327
328
Cornoound Narac
Glycerine
Hexachloroe thane
Hexylene glycol
Hydrogen cyanide
Hydroquinone
Isoamyl alcohol
Isobutanol
Isobutyl acetate
Isophorone
Isopropyl acetate
Isopropyl alcohol
Isopropyl amine
Ketene
Maleic anhydride
Mesityl oxide
Methacrylonitrile
Methyl acetate
Methyl alcohol
Methyl amine
N-Methyl aniline
Methyl chloride
Methyl cyclohexane
Methyl cyclohexaaol
Methyl cyclohexanone
Methylene chloride
Methyl ethyl ketone
Methyl formate
Methyl isobutyl carbinol
Methyl isobutyl ketone
a-Methyl styrene
Morpholine
Naphthalene
Nitrobenzene
Nttroethane
Nitrome thane
1-Nitropropane
2-Nitropropane
o-Nitrotoluene
p-Nitrotoluene
ra-Nitrotoluene
Pantaerythritol
n-Pentane
Perchloroethylene
Per chlorome thy Irae reap tan
usos (a ) ,
pptn
-
Is
25 Cc)
10s
-
100
100
150
25
250
400
5
0.5
0.25
25
Is
200
200
10
2s
100
500
100
100s
500
200
100
25 .
100
C 100
20s
10
Is
100
100
25
25
5s
5s
5s
-
1000
100
0.1
usos
10<0
10
125
11
2
360
300
700
140
950
980
12
0.9
1
100
'
610
260
12
9s
-
2000
470
-
-
590
250
100
410
480
70
50
5
310
250
90
90
30
30
30
10
2950
-
0.8
^M
MAC
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
100
5
1
-
5
50
-
-
- '
200
-
-
-
5
0.5
20
3
30
30
30
-
-
-
-
-
-
10
1
-------
1-4
TABLE 1-1. (Continued)
IOC
Number Compound Name
331 Phenol
336 p-Phenylenediamine
337 Phosgene
338 Phthalic anhydride
347 Propane
350 n-Propyl alcohol
355 Propylene dichloride
356 Propylene oxide
357 Pyridine
358 Resorcinol
368 Styrene
375 1,1,2,2-Tetrachloroethane
377 Tetraethyl lead
387 o-Toluidine
391 1,1,2-Trichloroethane
392 Trichloroethylene
393 Trichlorof luoromethane
394 1,2,3-Trichloropropane
395 1,1,2-Trichloropropane
397 Trie thy lainine
403 Vinyl acetate
404 Vinyl chloride
405 Vinylidene chloride
406 Vinyl toluene
407 m-Xylene
408 o-Xylene
409 p-Xylene
415G Xylidene (mixed)
(a) United States Occupational Standards
Substances (1.975 Edition).
(b) Maximum allowable concentrations, or
milligrams per cubic meter.
(c) Not necessarily USOS.
(d) Symbol "s" indicates skin absorption
USOSCa),
ppm
5s
-
0.1
2
1000
200
75
100
5
10
100
5
5s
10s
100
. 1000
50
1000
25
10
1
10
5s
-
0.5
1
-
10
10
Is
5
-
5
5
5 u-s/M3
3s
-
10
-
-
-
10
- .
30
10s
50
50
50
50
3s
Toxic Effects of Chemical
concentration (MFC)
in
(e) Symbol "C" indicates ceiling value, i.e, the worker's exposure shall at no tirna
exceed this value.
-------
1-5
TABLE 1-2. .MAXIMUM ALLOWABLE CONCENTRATION'S OF HARMFUL
COMPOUNDS IN WORKING-AREA ATMOSPHERE^3)
[Translated by D. K. Dreyer, Battelle]
Item
Number
2
3
4
7
. 9
10
11
12
13
14
16
18
19
20
21
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
40
41
42
46
47
48
49
Compound Name
Acrolein
Acrylic acid
Allyl cyanide
Amyl acetate
Primary aliphatic amines (Cy - Cg)
Higher aliphatic amines (C^j - C^g)
Of-Aminoanthraquinone
m-Aminobenzotrifluoride
5-Amino-8-oxy-3, 7 -dibromo-l,4-naphthoquinone inline
Aminopelargonic acid
Aminooenanthic acid (aininoheptanoic acid,
isomer unknown)
Anabasine-sulphate (3-(2-piperidyl) pyridyl sulphate).
p-Anisidine (p-aminoanisole)
Aniline
Blue dispersed anthraquinone dye "K" (mixture 50%
l-methylaraino-4-oxyethylaminoanthraquinone and 50%
disodium salt dinaphthylamine disulphonic acid)
Acetaldehyde
Acetone
Acetonanyl (2,2,4-trimethyl-l,2-dihydroquinoline)
Acetone cyanohydrine
Acetopropylacetate (propyl ester of acetoacetic acid)
Acetophenone
Benzal chloride
Benzyl chloride
Benzyl cyanide
Benzine solvent (on conversion to C) (petroleum
distillate, mostly aliphatic)
Benzine-fuel (shale, cracking and others) (on
conversion to C)
Benzoyl chloride
Benzene
Benzotrifrluoride
Ben zo trichloride
p-Benzoquinone
Bischloromethylbenzene
Bischloromethylxylene
Bischloromethylnaphthalene
Bromocetopropylacetate
Broraobenzene
Bromoforra
Butyl acetate
MAC.
ms/M3
0.7
5
0.3s
100
1
1
5
0.5
1
8
8
0.1
Is
3s
5
5
200
1
0.9s
5
5s
0.5
0.5
0.8s
300
100
5
5s
100
0.2
0.05
1
1
0.5
0.5
3
5
200
Physical
State(c)
V
V
V
V
V
v+a
a
V
a
a
a.
v+a
V
V
a
a
V
a
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
-------
1-6
TABLE 1-2. (Continued)
Item
Number
51
52
53
55
56
57
59
60
61
62
63
65
66
67
68
69
70
71
72
73
78
79
80
84
85
86
87
88
89
91
93
94
95
96
97
98
99
100
101
102
103
104
105
Compound Name
Butyl acrylatc
Butyl ester of 5-chlorotnethyl-l-furoic acid
Butyl ester o£ 2-furoic acid
Butynediol
Butyphos (tributyltrithiophosphate)
Valerianic acid
Vinyl acetate
Vinylbutyl ether
2-Vinylpyridine
Vinyltoluene
Vinyl chloride
Hexaraethylene diamine
Hexamethylene diisocyanate
Kexamethylene imine
Hexachlorocyclohexana
y-hexachlorane (y-hexachlorocyclohexane)
Hexachloroacetone
Hexachlorobenzene
Hexach lor ocycl open tad iene
Hexafluoropropylene
Hydrazine -hydrate, hydrazine and its derivatives
8-Hyd r oxye thy line r ca p tan
Isopropylbenzene hydroperoxide
Decalin
1,2-Dibroraopropane
Divinyl (1,3-butadiene pseudobutylene)
Perfluoroacetone dihydrate
Diisopropylamine
Disopropylfaenzane
Dicurayl methane ,
Dime thy lamine
Dime thy laniline
Dime thy Ibenzy lamina
Dimethyldioxane
Dimethyl sulphide
Dimethylterephthalate
Dime thy Iformamide
Dime thy Ich lor othiophosphate
Dime thy lethanolatnine
Dinyl (mixture of 257. diphenyl and 757. diphenyl oxide)
Dinitrobenzene
4, 6-Dinitro-2-isopropyl phenol
Dinitro-o-cresol
MAC(b),
mc;A!3
10
0.5
0.5
1
0.6s
5
10
20
0.5s
50
30
1
0.05s
0.5s
0.1
.. 0.05s
0.5
0.9s
0.01s
5
O.ls
Is
1
100
5
100
2s
5
50s
5s
1
0.2s
5
10
50s
0.1
10
0.5
5
10
Is.
0.05s
0.05s
Phsical
Stated)
V
a
a
v+a
v+a
V
V
V
V
V
V
V
V
V
v4-a
v-fa
V
v+a
V
V
V
V
V
V
V
V
V
V
V
a
V
V
V
V
V
v+a
V
V
V
v+a
v+a
v+a
v+a
-------
1-7
TABLE 1-2. (Continued)
Item
Number
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
Compound Name
Dinitrotoluene
Dinitrophenol
Dinitro-secondary-butyl phenol
Dinitrile of adlpic acid
Dinitrile of perf luoroglutaric acid
Dinitrile of parfluoroadipic acid
Dinitrothiocyanogenbenzene (probably 3,5-dinitro-l-
thiocyanobenzene)
Dioxane
Diptane (diisopropyltrichloroallylthiocarbamate)
Di-n-Propylainine , tri-n-propy lamina
Ditertiarybutyl peroxide
Ditolylme thane
Chlorinated diphenyls
Chlorinated diphenyl oxide
Diphenylolpropane (Bisphenol A)
3,4-Dichloroaniline
Dichlorobenzene.
l,3-Dichlorobutene-2
Dichlorohydrin
1,2-Dichloroisobutsne
1,3-Dichloroisobutylene
3,3-Dichloroisobutylene (symnetric isoiner)
3,3-Dichloromethyloxacyclobutane
2,3-Dichloro-l,4-naphthoquiinone
3,4-Dichloronitrobenzene
1,2-Dichloropropane
1,3-Dichloropropylene
2,3-Dichloropropylene
3,4-Dichlorophenylisocyanate
Dichlorophenyltrichlorosilane (HC1 verification
obligatory)
Dich lor oe thane
1,1-Dichloroethylene (vinylidene chloride)
Dicyclopentadiene
Diethylamine
8-Diethylaminoethylr.ercaptane
Diethylaminoethyl methacrylate
Diethylbenzene
Diethyl ester of perfluoroadipic acid
Diethyl ester of perf luoroglutaric acid
Diethylchlorothiophosphate
Diethylethanolamine
Dodecylmercaptane (tertiary)
Isobutylene
Isobutylene chloride
MAC(b),
mg/M3
Is
0.05s
0.05s
20
0.05
0.1
2s
10s
1
2
100
1
Is
0.5s
5
0.5s
20s
1
5
20
0.5
0.3
0.5
0.5
Is
10
5
3
0.3
1
10s
10s
Is
30
Is
800
10
0.1
0.1
1
5
5
100
0.3
Physical
State(c)
v+a
v+a
v+a
V
V
V
a
V
v+a
V
V
v+a
V
V
a
V
V
V
V
V
V
V
V
a
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
-------
1-8
TABLE 1-2. (Continued)
Item
Number
150
151
152
153
154
155
156
157
162
163
164
168
171
172
173
174
175
177
178
179
180
185
186 .
189
190
191
192
193
194
195
196
197
198
199
200
203
205
206
207
208
209
210
Compound Name
Isoprene
Isopropylaminodiphenylamine
Isopropylbenzene (cunene) '
Isopropylnitrate
Isopropylnitrite
.Isopropylchlorocarbonate
Isopropyl-N-phenylcarbaraate
Isopropyl-N-3-chlorophenylcarbamate
Camphor
Caprolactam
Caproic acid
Kerosene (in conversion to C)
Crotonaldehyde
Butylic K Xanthogenata
Xylidine
Xylene
Ligroin (in conversion to C)
Butyraldehyde
Butyric anhydride
Butyric acid
Maleic anhydride
Methacrylic acid
Methacrylic acid anhydride
Methyl acetate
Methyl bromide
Methyl chloride
2-Methyl-5-vinylpyridine
6-Mathyl-2-vinylpyridine
Methyl hexyl ketone
Methylene bromide
Methylene chloride
Methyl vinyl katone.
'Methylthiophene (2 and 3 isomers)
Me thy Id ihyd r o py r ane
Methylisothiocyanate
1-Methylnaphthaline, 2 -me thy Inaphtha line
Methyl acrylate
Methylpyrrolidone
Methyl propyl ketone
MethylEluorophenyldichlorosilane (obligatory HC1
control)
Methyl chloroacetate
Methylcyclohexane
MAC('))>
40
2
50
5
Is
0.1
2
2
3
10-
5
300
0.5
10
3s
50
300
0.5
1
10
1
10
1
100
1
5
2s
0.5s
200
10
50
O.ls
20
5s
O.ls
20
20
100
200
1
5
50
Physical
Stated)
V
a
V
V
V
V
v+a
v+a
V
a
V
V
V
a
V
V
V
V
V
V
v+a
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
V
v+a
V
V
V
V
-------
1-9
TABLE 1-2. (Continued)
Item
Number
211
212
217
218
219
220
221
222
223
224
225
226
229
230
231
232
236
237
238
239
240
241
242
243
244
245
246
249
250
252
253
254
255
257
258
259
260
261
262
263
264
265
266
Compound Narae
Methyl ethyl ketone
2-Methyl-5-cthylpyridlne
Monobuty lamina
Monovinyl acetylene
Monoisopropylamine
Monome thy lamina
m-Monomothyl ether of resorcinol
Monochlorod ibromotr if luoroe thane
Monochloroditnethyl ether
Monochloro-, dichlorostyrene
Monochlorocyclohexane
Morpholine
Sodium thiocyanate (technical)
Naphthalene
Chlorinated naphthalines (high)
O/-Naphthoquinone
Nicotine sulphate (3-(l-methyl-2-pyrrolidyl)pyridine
sulphate)
Nitrophene (containing alkylphenols 72.5-67.5%)
Acrylonitrile
p-Nitroanisole
p-Nitroaniline
o-Nitroaniline
m-Nitrobenzotrifluoride
Nitromethane, nitroethane, nitropropane, nitrobutane
Nitroxylene
Nitrocompounds of benzene
Nitroform
Nitrochlorobenzene, dinitrochlorocompounds of benzene
Ni trocyc lohexane
p-Oxyd iphenylamine
Oxycarbatnate
Octamethyl (octataethyltetramide of pyrophosphoric acid)
Octafluorodichlorocyclohexene
Pentafluoropropionic acid
Pentachloroacetone
Pentachloronitrobenzene
Pen tachloro phenol
Pentachlorophenolate of sodium
Perfluoroisobutylene
Perchloromcthylmercaptan
Picoltnes (mixture of isomers)
Piperidine
Pyridine
MAC
-------
1-10
TABLE 1-2. (Continued)
Item
Number
275
276
277
278
279
280
291
294
295
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
325
326
327
328
329
330
331
332
333
334
335
336
337
Compound Kama
Propanide (3,4-dlchloropropione anilidc)
Propylene oxtda
n-Propylamine
Propylacctate
Propylpropionate
Proplonic aldehyde
Carbon disulCide
Spirits of turpentine (on conversion to C)
Solvent naphtha (on conversion to C)
Unsaturated alchols of the fatty series (allyl,
crotonyl, etc)
Methyl alcohol (methanol)
Ethyl alcohol
Propyl alcohol
Amyl alcohol
Acetopropyl alcohol
Butyl alcohol
n-Haxylic alcohol
n-Haptyl alcohol
n-Octyl alcohol
n-Nonyl alcohol
n-Decyl alcohol
Propargyl alcohol
Octafluoroamyl alcohol
Trifluorobutyl alcohol
Trifluoroethyl alcohol
Tetrafluoropropyl alcohol
Isooctyl alcohol (2-ethylhexanol)
Styrene, a-methylstyrene
Terephthalic acid
Te trabronie thane
Tetrahydrofuran
Tetralin
Tetranitrome thane
Tetrachlorohexatriene
Tetrachloropropane, tetrachloropentane, tetra-
chloroheptane
Te tr a ch lor on onane
Tetrachlorundecane
Tetrachloroe thane
Tetrachloroethylene
Tetraethyl lead
Tetraethoxysilane
MAC(b),
tnf>/M3
0.1
Is
5
200
70
5
10
300
100
2
5
1000
10
10
" 10
10
10
10
10
10
10
1
20
20
10
20
50
5
0.1
1
100
100
0.3
0.3s
1
1
5
5s
10
0.005s
20
Physical
Stated
a
V
V
V
V
V
V
V
V
V
V
V
V
V
V .
V
V
V
v+a
v+a
v+a
V
V
V
V
V
V
V
v+a
V
V
V
V
V
V
v+a
v+a
V
V
V
V
-------
1-11
TABLE 1-2. (Continued)
Item
Number
339
341
343
345
346
347
348
350
351
352
353
355
356
357
358
359
360
361
362
363
365
366
367
368
369
.370
371
372
375
376
377
380
381
382
383
385
386
387
392
397
398
402
403
404
Compound Name
Thioglycolic acid
Thiophone
Thiuram, TMTD (tetramethylthiuram disulfide)
Toluidine
Toluene diamine
Toluene diisocyanate
Toluene
Tertiary-butylperacetate
Tertiary-butylperbenzoate
Tricresylphosphate, containing more than 37. orthoisomers
Tricresylphosphate, containing less than 37. orthoisomers
Trimethylamine
Trime thy lol propane
Trinitrotoluene
1, 1,3-Trichloroacetone
Trichlorobenzene
Trichloro pro pane
Trichloropropylene
Trichlorosilane (obligatory HC1 verification)
Trichloroa thy lane
Trichloronaphthalene (mixture of tetra- and penta-
chloronaphthalenes)
Copper trichlorophenolate
Trifluoropropylamine
Trif luoroacetic acid
Trifluorochloropropane
Trifluoroethylamine
Triethylamine
Triethoxysilane
Saturated aliphatic hydrocarbons Cj - C^Q (on conver-
sion to C)
Carbon tetrachloride
Acetic acid
p-Phenetidine hydrochloride (? chloride)
Phenylmethyldichlorosilane (HC1 control obligatory)
m- Phen oxy phe no 1
Phenol
Formaldehyde
Fortnamidc
Phosgene
Phthalic anhydride
Furan
Furfural
p-Chloraniline
Trichloroacetyl chloride
Acid chloride at acrylic, methacrylic acids
C$>
O.ls
20
0.5
3s
2s
0.5
50
0.1
1
. O.ls
0.5s
5
50
Is
0.3
10
2
3
1
10
Is
0.1
5
2
Is
100
10
1
300
20s
5
0.5
1
Is
5s
0.5
3
0.5
. 1
0.5
10
0.3s
O.ls
0.3
Physical
Sta'te(c>
v+a
V
a
V
v+a
V
V
V
V
a
a
V
V
V
V
V
V
V
V
V
v+a
a
V
V
V
V
V
V
V
V
V
a
V
V
V
V
V
V
v+a
V
V
V
V
V
-------
i-ii
TABLE 1-2. (Continued)
Item
Numbe r
405
406
407
408
409
412
414
415
417
418
419
420
422
425
426
427
428
429
430
.431
432
434
440
442
443
444
445
446
447
448
449
450
453
454
455
456
457
Compound Name
n-Chloroaniline
Chloroacetopropylacetate
Chlorobenzene
1,3-Chlorobromopropane
4-Chlorobenzophenol-2-carboxylic acid
5-Ethoxyphenyl-l,2-thiazothionic chloride
Chloromethyltrichlorosilane (HC1 control obligatory)
Chloroprene
Chloropropionic acid
Chloropelargonic acid
m-Chlorophenylisocyanate, p-chlorophenylisocyanate
m-Chlorophenol
2-Chloroethanesulfochloride
Cyanuric chloride (trichlorotriazine)
Free cyanaraide
Cyclohexane
Cyclohexanone
Cyc lohexy lamine
Cyclohexylarains carbonate
Cyclohexylamine chroma te
Cyclohexanone oxime
Cyclopentadiene
Epichlorohydrin -
2-Ethylhexenal
Ethylacetate
Ethylene oxide
Ethylene diamine
Ethylene imine
.Ethylene sulfide
Ethylene diacetate
Ethylene chlorohydrin
Ethylmercaptan
Ethyl ether, diethyl ether
. Ethyltoluene
Ethyl bromide
Ethyl chloride
Ether sulfanate (?) (p-chlorophenyl-p-chlorobenzo-
sulfanate)
MAC
-------
1-13
TABLE 1-3. MAXIMUM ALLOWABLE CONCENTRATIONS OF HARMFUL
SUBSTANCES IN ATMOSPHERIC AIR OF INHABITED
AREAS - USSR
------- |