UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
"SUBJECT:" xne Meeiianicm'Whe.reby Methane Gas is Generated in an   DATR: August'16. 1974
         Anaerobic Digestion of Organic Material

 FROM:   Edniond P. Lomasney Ł?V,
         Region IV, Research & Development Program

 TO:      Regional Personnel
         SUMMARY

              We take it for granted that most everything worth-knowing about
         anaerobic digestion of organics has appeared in the literature and
         that the process is well understood.  This is not so—in fact, a good
         deal of the published literature regarding tho behavior of this process
         'may be misleading, especially as concerns the mechanism for generation
         of methane.

              In January of this year, the attached paper pertaining to this
         subject was presented at an agricultural seminar in Atlanta.  At that
         time there unfortunately were no printed copies available, though
         many requests were mads for copies.  Recently, we have obtained
         copies and as a consequence I am forwarding the attached for your
         edification.

         ACTION

              None—the paper is only intended for educational purposes; relating
         to a biological process for the generation of energy.

         BACKGROUND                               .          •         '          .

              Our program has had research projects which utilized anaerobic
         digestion procedure for organics and have yielded strange or unusual
         results.  Some of the reasons for this behavior are indirectly related
         to the subject matter of the attachment.  Though in many respects the
         generation of methane by this process was considered s known fact,
         there \»ere times when a specific i-naerobic process performed in a
         relatively inefficient manner for no apparent reason; methane production
         ceased with, the system going sour.  With the information generated by
         Dr. Paul H. Smith at the University of Florida, Gainesville, \ve wers
         able to have a more thorough understanding of the anaerobic system for
         generation of methane, and consequently avoid the pitfalls experienced
         in the past.
 EPA Form 1320.-6 (Rev. 6-72)

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 Distribution List;

 Dr,  Helen McCammon,  Region  I,  Boston,  MA
.Dr.  Robert W.  Mason,  Region II,  New  York, NY
 Albert Montague,  Region III, Philadelphia, PA
 Clifford Risley-,  Jr.,  Region V,  Chicago,  IL
 Mildred Smith,  Region VI, Dallas,  TX
 Aleck Alexander,  Region VII, Kansas  City, MO
 Russell W.  Fitch, Region VIII, Denver, CO
>Vern Tenney, Region  IX.  San Francisco, CA
 Robert Courson, Region X, Seattle, V/A

 William T.  Willis, Alabama  Department  of  Health, Montgomery, AL
 Peter P.  Baljet,  Florida Department  of Pollution-Control.
   Tallahassee,  FL             '  .
 R.  S. Howard,  Jr., Department  of Natural  Resources, Atlanta, GA
 Herman D.  Regan,  Department of Natural Resources & Environmental
   Protection,  Frankfort, KY
 Glen Wood,  Jr. , Mississippi Air  & V/ater Pollution Control Commission,
   Jackson,  MS
 Earl C. Hubbard,  North Carolina  Department of Natural & Economic
   Resources, Raleigh,  NC
 Dr.  E.  Kenneth Aycock,  South Carolina  Department of Health &
   Environmental Control, Columbia, SC
 Dr.  Eugene W.  Fowinkle,  Department of  Public Health, Nashville, TN

 Dr.  John F.  Andrews,  Clemson University.  .Clemson. SC
 Dr.  Robert Inpols, Geoi-gia  Institute of Technology, Atlanta, GA
 Dr.  Paul H.  Smith, University  of Florida, Gainesville, FL

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                                                                 11581
       SOUTHEASTERN POULTRY AND  EGG ASSOCIATION SEMINAR

                       Atlanta,  Georgia
                       January 30, 1974
        TECHNOLOGY OF METHANE CAS PRODUCTION RELATED TO
            ANAEROBIC DICESTION OF ORGANIC MATERIAL
                      Edmond P. Lomasney
        Research and Development Program Representative
                Environmental Protection Agency
                      Southeast Region IV
Presented through the  courtesy of:

Dr. Paul H.  Smith, Project Director, University of Florida,
  Gainesville,  Florida

Cecil Chambers, Project Officer, National Environmental  Research
  Center, Environmental Protection Agency, Cincinnati, Ohio

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For Figures, Charts, Graphs,  Tables and Pictures



                 see Appendix

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                Anaerobic Digestion of Organic Material

                 •

     This presentation is a summary of work conducted under an EPA

                      (
Grant on the breakdown of organic material under anaerobic conditions.


The work deals with the conversion of complex organic matter such as


the material found in domestic and agricultural wastes to methane

and carbon dioxide.  The conversion is attractive for waste disposal


because the products are innocuous, the conversion rates rapid, and

the process is economical.  The process requires little energy input


and produces a product, methane, which may be utilizable as a secondary


energy source'.  The anaerobic digestion processes, however, are made

unattractive by the current limited ability for control and regulation:

It is probable that our limited abilities to control and regulate the


process is based on our limited knowledge of the critical biological


steps involved.  I shall deal largely with this subject.

     The first figure, one (1) , illustrates the generally accepted


concept of the steps involved in the conversion of insoluble organic


material to methane and carbon dioxide.  In this scheme there is a


conversion of insoluble organic material to soluble organic material,


catalyzed by a wide variety of extra-cellular enzymes.  The existence

of this step has been convincingly demonstrated by a large amount of

experimental evidence.  Organisms and enzymes capable of carrying out


this step have been isolated and studied over a long period of time.

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                                  -2-




 Similarly  step  two  has  been definitely established.  In this step




 soluble organics are converted to volatile acids, plus hydrogen and




 carbon dioxide.  Step three however has never been experimentally




 verified.  Volatile acids, primarily acetate, propionate, and butyrate,




 have been  isolated, but repeated  efforts in many laboratories to




 culture organisms capable of metabolizing these acids have all failed.




 The reason these efforts have failed is that the supposition of the




 scheme is not correct.  Contrary  to the general view, the digestion




 of complex organic  substances consists of four stages, as shown in




 the second figure,  two  (2).  Digestion consists of:  hydrolysis of




 complex organic molecules, acid production, hydrogenogenesis from




 acids, and methane  formation.  The second scheme differs from the




 first scheme in that some fatty acids are converted to hydrogen and




 carbon dioxide prior to the formation of methane, by a microflora that




 does not produce methane.  What evidence, you may ask, exists in




 support of the second scheme.  I shall now discuss the shaded part of




 the four stage scheme since this is the portion which differs from




 the three stage scheme.   If the new scheme is correct, it should be




possible to quantitatively demonstrate volatile acids including




acetate,  as intermediates in the process using isotope dilution




 techniques.  With this technique a rate constant is calculated from




a linear change in specific activity of added radioactive label.




This constant multip"ica by the fatty acid pool size gives the rate

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                                 -3-



of  formation of  the acid which is then used to calculate the percentage



contribution of  the specific acid to total methanogenesis.  Such rate



constants were experimentally determined as shown in the third



figure, three (3).  This graph shows a linear change in a plot of



the log of counts pur minutes in acetate against time in a fermentation



producing methane at a rate of 0.033 micromoles per milliliter per



minute.  From the da«.a on this graph a rate constant of 0.0052 per



minute Is obtained.  The acetic acid pool size in the samples was



4.7 micromoies/mllli iter.  The product of the rate constant times



the pool size gives a rate of formation of acetic ccid of 0.024



micromoles per milliliter per minute.  Assuming that 1 mole of methane



is formed from 1 mole of acetic acid, the acetic acid would account



for approximately 73% of the methane produced during the fermentation.



In the fourth figux\,, four (4) , similar experiments with propionic



acid, n-butyric acid and isobutyric acid show that 93% * 5% of the



methane formed during digestion of domestic waste, had these volatile



acids as intermediates.   The results show a mintdial contribution of



the fatty acids to methane of approximately 90% leaving 10% for



hydrOfodn and other oxidizable substrates.  In the fifth figure, five (5),



the experiments also show that acetate was formed 40% from butyrate



and 23% from propionate.



     T,.-se results are in agreement with both schemes.  Sludge would



vapicuy metabolise toe fatvy acids, and hydrogen and carbon dioxide

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                                  -4-




were also  rapidly converted  to methane.  Efforts  to  isolate  fatty




acid and hydrogen utilizing  methanogenic bacteria resulted in  the




isolation  of n Itu^o Dumber  of methanogenic bacteria from the  sludge.




la the sixth figure, six  (6), the picture shows some bacterial  species




isolated from hign dilutions of sludge.  All of these isolates  were




present in digestiiij sludge  in numbers exceeding  one million per




•llliliter.  The large sarcina converts acetate to methane and




carbon dioxide.  Vi.c others  all form methane from hydrogen and  carbon




dioxide but will now produce methane from fatty acids.  Figure  seven  (7)




shows bacteria representing other isolates from sludge.  They all form




methane from hydrogen and carbon  dioxide but do not  metabolize  fatty




acids.  Figure eight (8) shows a  spirillum, isolated from a high




dilution of a propionate enrichment, which is methanogenic and




metabolizes hydrogen and carbon dioxide but not fatty acids.




Figure nine (9) represents a colony of the spirillum and is Included




to show its beauty.




     The large mui.~ar of hydrogen oxiax^ing raethanogenic bacteria in




digesting  sludge suggested that the capacity of digesting sludge for




hydrogen luetaboli^r.t should bo great.  Cupacity of digesting sludge




for hydrogen metabolism was detc,k-ttined by incubating digesting  sludge




under a gas phase ox' 70% hycu-ogen ^»d 30% carbon  dioxide.  Hydrogen




uptake and methane z'or~.ation -ere ^jCo»-ciined quantitatively.  Methane




formation was uli,. quantitatively determined for  digesting sludge

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                                 -5-




 incubated under & gas phase of 70% nitrogen and 30% carbon dioxide.




 The  results are shown In figure ten (10).  Taking average value*,




 447  mlcromoles of hydrogen were utilized in the hydrogen flasks and




 210  micromoles of methane was formed.  Assuming 1 micromole of




 methane  from 4 raicroraoles of hydrogen, 112 raicromoles of methane




 would have been produced from added hydrogen and carbon dioxide,




 leaving  98 micromoles of methane formed from the sludge.  However,




 134  raicromoles of methane were produced from sludge in the nitrogen




 flasks.  The difference between the 134 micromoles of methane




 produced from sludge in the absence of added hydrogen and the 98




 micromoles calculated from sludge in the presence of hydrogen indicates




 that either hydrogen inhibited methane production from other sludge




 precursors, or hydrogen and carbon dioxide were converted to molecules




 other than methane.   The rate of methane formation was determined




 for  sludge samples which had been equilibrated for two hours with  a




 gas  phase of 70% hydrogen and 30% carbon dioxide.  This rate was




 compared to the rate of methanogenesis ?s?om sludge which had been




 equilibrated for two hours with a gas phase of 70% nitrogen and 30%




 carbon dioxide as shown on the next figure, eleven (11).  The rates




were calculated from the methane evolved during the seventy-five




minutes iomediately following the equilibration period.  The lowered




rate of methane evolution following exposure to hydrogen gas shows




 that an inhibition of raethaaoganesis had occurred.  Calculations from

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                                  -6-




 average values  oi  c.;.^.-> utilization and production given in next to




 last  table show „.. inhibition of 30% during exposure to a 70%




 hydrogen atmospnezv.




      The data suggests that  hydrogen inhibits  the methane formation




 from  some substrates  other than  hydrogen.   In  figure twelve (12),




 the 30% inhibition corresponds to the total methane expected from




 propionate.  This  graph shows that  turnover of propionic acid




 metabolism was  stvoagly inhibited by hydrogen  since in the presence




 of molecular hyarcgen labeled propionic acid was not diluted,




 suggesting that a^.  important  ecc  jgical role of  the hydrogen oxidising




 methanogenic bacteria in dissimulation processes is the maintenance




 of a hydrogen concentration low  enough to prevent the inhibition  of




 propionic  acid metabolism, and the  concurrent  cessation of the




 fermentation.




     Efforts were made to isolate methanogenic bacteria from propionic




 acid enrichments.  In every case  the enrichments were found to contain




large numbers of i. .irogen oxidizing raethanogenic bacteria.   These




 organism^,  could dot metabolize propionate,  sugge^ing that propionate




 metabolism result-*- in the formation of i^ee molecular hydrogen which




 served as  tl,.; • suo.,..rate for the growth of the  hydrogen oxidizing




methanogens which v._re isolated.




     Propionate Jxci .  ou ri c.v..ife.'. »s  wevc u..e;\  ustabi^shed under an




atmosphere «f lix/t carbon dioxiae.   The enrichments were ihen fed




 propionate and vi,.  ously ga&ed with 100% carbon dioxide.

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                                 -7-




     A carbon dioxide absorbing train was placed at the outlet of the



 fermentation vessel.  The carbon dioxide was absorbed in potassium



 hydroxide  and the remaining gas analyzed.  The concept here is that



 under  the  experimental conditions created where hydrogen was formed



 from propionate, most of it would be removed from the fermentation



 liquid before it could be converted to methane and would then be



 present in the collected gas.  This would be consistent with the new



 scheme.  If propionate were converted directly to methane (as proposed



 in the old scheme) then there would be no hydrogen in the collected gas.



     The results are shown in figure thirteen (13).  A large amount of



 hydrogen was obtained.  This definitely demonstrates a formation of



 molecular  hydrogen from propionate.  Similar experiments are in progress



with butyrate.  Butyrate enrichments yield hydrogen utilizing



 methanogenic bacteria which lack the capacity to metabolize butyrate.



     The data demonstrates a four step process in methane formation



 from organic natter.





     Every bit of this constitutes basic considerations in terms of



 the methane production via biological processes.   Much of the past



information relating to the methanogenic bacterial process has been



misleading.  The correct interpretation of this basic phenomena must



be understood before we can tap this source of gaseous energy.



The information and data disclosed in this presentation is the result



of long-term work by Dr.  Paul H.  Smith at the University of Florida,

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                                  -.5




          e, under  funding provisions by the Environmental Protuc  ic




Agency, Research and  Development Program.  At present, Dr. Smith




»v-.ntinues to investigate  this  subjtct, and further disclosures on




;1'(.3 i^chaniso oi: fe-ciogici?.!  ssathane production will u -.doubter^; '

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Appendix

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    FIGURE 1
   INSOLUBLE
   ORGANICS
   SOLUBLE
   ORGANICS
VOUTILE
         CO.

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             FIGURE 2
              INSOLUBLE
              ORGANICS
                 I
              SOLUBLE
              ORGANICS
VOLATIte
   OTtfSR
    ACSTATC
 ^ C0a
AND

OH

^
(*co8
!

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              ACETIC ACID
       TURNOVER  NUMBER DETERMINATION
    395
UJ
H-

Z
5
CC
UJ O
O UJ
O O
,,_< 385
e>
o
     380
                             FLA5K-2
              10     20     30     40

                 TIME  IN MINUTES
                                         50
                   FIGURE 3
 PRECURSORS OF METHANE IN DOMESTIC SLUDGE
                       of Total Methane
 Acetic Acid
 Propionic Acid
 n-Butyric Acid
 Isobutyric Acid
 Formic Acid
                            73
                            13
   TOTAL
                FIGURE

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PRECURSORS OF ACETIC ACID IN  DOMESTIC  SLUDGE
     Precursor
Butyric acid



Propionic acid



Others
% of total acetic  acid
         40



         23



         37
                                                                      I i
                    FIGURE 5
                     FIGURE 6

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      \
FIGURE 7
I a.
FIGURE 8

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                 FIGURE 9
HYDROGEN UTILIZATION  BY  DOMESTIC SLUDGE
Gas Phase
70%"H2, 30% C02
,.
7,.:/0 N2, 30% C02
ii
CH4 Formed
in p.mole
207
214
132
136
Initial H2
ia ;i mole
1650
1695
0
f
i
Final H2
in u^nole
1220
1230
3
3
                 FIGURE 10

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   EFFECT  OF HYDROGEN GAS  ON SLUDGE METHANOGENESIS
Treatment Prior
to Inoculation
Exposed to H2 gas*
u it 11
Exposed to N2 gas+
u u M
i.'ll_j l-\>t nu-d
in :i mole
62
66
75
78
in |i mole/ml min"l
0.017
0.018
0.020
0.021
*  Equilibrated with 70% H2  ahd 30% C02 for  two hours.
+  Equilibrated with 70% N_  and 30% CO2 for  two hours.

                       FIGUflE H
  w u
  d H
  CO O
    2
  8
  ,4
                5  10  15  i';  20
                     TIMK  IN MINUTES
                 x  HT in 9'TS phase
                 o  N2 in gas phase
                       FIGURE J2

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TIME IN
MINUTES
1 -10
10- 20
20-30
30-40
40 - 50
50 -60
PERCENT
HYDROGEN
0.9
40
43
43
43
43
PERCENT
METHANE
99
60
57
5 7
5 7
57
FIGUE 15

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