GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
SIMAZINE
AS THE ACTIVE INGREDIENT
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D.C. 20460
MARCH 1, 1984
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TABLE OF CONTENTS
Introduction . . 1
I. Regulatory Position 4
II. Requirement for Submission of Generic Data 74
III. Requirement for Submission of Product-Specific
Data 114
IV. Submission of Revised Labeling and Packaging
Information. . . 115
A. Label Contents . . , 115
1. Product Name 115
2. Company Name and Address 115
3. Net Contents
4. Product Registration Number 116
5. Producing Establishment
Registration Number . . 116
6A Ingredient Statement . .
6B Pounds Per Gallon Statement . lie
7. Front Panel Precautionary Statements 116
7A Child Hazard Warning Statements 117
7B Signal Word 117
7C Skull and Crossbones and Word Poison ...... 117
7D Statement of Practical Treatment . . 117
7E Referral Statement ....... ^ . 117
8. Side/Back Panel Precautionary Labeling 117
8A Hazard to Humans and Domestic Animals. us
8B Environmental Hazard 118
8C Physical or Chemical Hazard. . . . us
9 Misuse Statement 119
10A Storage and Disposal Block 119
10B Directions for Use 119
B. Collateral Information 119
V. Instructions for Submission 120
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APPENDICES
II-l Bibliography
II-2 FIFRA §3(c)(2)(B) Summary Sheet - EPA Form 8580-1
II-3 Certification of Attempt to Enter Into an Agreement
With Other Registrants for Development of Data
EPA Form 8580-6
III-l Product Specific Data Report (End-Use Products)
EPA Form 8580-4
IV-2 Table of Labeling Requirements and Sample Labels
IV-3 Physical/Chemical Hazards Labeling Statement
IV-5 Storage and Disposal Statements
Note: Appendices IV-1, IV-4 and IV-6 are not germane to this
document and are not included.
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INTRODUCTION
The Federal Insecticide, Fungicide, and Rodenticide Act
(FIFRA Section 3(g), as amended in 1978, directs EPA to
reregister all pesticides as expeditiously as possible.
Each registrant of a manufacturing use product of the active
ingredient who wishes to continue to sell or distribute that
product must apply for reregistration.
To fulfill this Congressional mandate, we have established
the Registration Standards program which will review all pesti-
cide active ingredients first registered before January 1,
1977. These pesticides will be reviewed in use clusters
which are prioritized on the basis of a ranking scheme giving
preference to pesticides used on food and feed crops.
The Registration Standards program involves a thorough
review of the scientific data base underlying pesticide
registrations and an identification of essential but missing
studies which may not have been required when the product
was initially registered or studies that are now considered
insufficient. Our reassessment results in the development
of a regulatory position, contained in this document, on
each pesticide and its uses. The regulatory position may
require the registrant to modify product labels to provide
additional precautionary statements, restrict the use of the
pesticide to certified applicators, provide reentry intervals,
modify uses or formulation types, specify certain packaging
limitations, or other requirements to assure that proper use
of the pesticide poses no potential adverse effects to human
health or the environment.
The scientific review, which is not contained herein
but is available upon request, concentrates on the technical
grade of the active ingredient and identifies missing generic
data. However, during the review of these data we are also
looking for potential hazards that may be associated with
the formulated (end-use) products that contain the active
ingredient. If we find serious concerns, we will bring
formulated products under the provisions of the Registration
Standards program to the extent necessary to protect the
public.
EPA has the authority under FIFRA §3(c)(2)(B) to require
that certain registrants submit generic data that will answer
our questions regarding the hazard that may result from the
intended use of the pesticide under review. Further, §3(c)
(2)(B) provides that these data are to be submitted by
those registrants who do not qualify for the formulator's
exemption [FIFRA §3(c)(2)(D)]. Normally, this means that
the registrants who are responsible for filling the data
gaps are the manufacturing-use product producers (basic
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suppliers of the active ingredient). However, end-use producers
will not qualify for the formulator's exemption if the source
of their active ingredient: (1) is not registered with EPA,
and/or (2) is produced by the registrant's firm, or a firm
which has ownership in common with the registrant's firm.
These end-use producers can qualify for the formulator's
exemption if they change their source of supply to a registered
source, provided the source does not share ownership in
common with the registrant's firm. If the end-use product
registrant decides to switch sources, a new Confidential
Statement of Formula, EPA Form 8570-4, must be submitted to
the appropriate Product Manager within 90 days of receipt of
this Guidance Document. The chart on the following page
shows what is generally required of those who do and do not
qualify for the formulator's exemption in the Registration
Standards program.
If you decide to request the Agency to discontinue the
registration of any of your products subject to the reregistra-
tion requirements of this Guidance Document, please notify
the Product Manager named in the cover letter, within 90
days from the receipt of this document, that you wish to
voluntarily cancel the registration(s). If you decide to
maintain your product registration(s), you must provide the
information described in the following pages within the time-
frames outlined. EPA will issue a notice of intent to cancel
or suspend the registration of any currently registered
product if you fail to comply with the requirements set
forth in this Guidance Document.
This Guidance Document will be supplemented by EPA with
additional, information about compliance with data support
requirements. In Monsanto v. Administrator, EPA was recently
enjoined from implementing in any way the "mandatory data
licensing" aspects of S3(c)(l)(D) of FIFRA. EPA is assessing
the implications of the injunction for the reregistration
process. .Because this situation is currently unresolved, EPA
has decided to proceed with the requirements in this Guidance
Document which do not relate to compliance with the §3(c)(l)(D)
provisions and to supplement the Document with additional
guidance when circumstances permit. Failure to comply with
the provisions of the subsequent guidance will also result
in issuance by EPA of an intent to cancel the affected product
registration(s).
Registrants are reminded that §6(a)(2) of FIFRA requires
you at any time to submit factual information raising concerns
of possible unreasonable adverse effects of a pesticide. You
should notify the Agency of interim results of studies in
progress if those results show possible adverse effects.
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PRODUCTS SUBJECT TO THE
REGISTRATION STANDARDS PROGRAM
ACTION(S) REQUIRED TO
MAINTAIN REGISTRATION
I. Products That Do Not Qualify
For The Formulator's Exemption
A. Single Active Ingredient
Products*
These products must be reregis-
tered. To obtain reregistration,
labeling, packaging and data
requirements must be satisfied
in accordance with the Regis-
tration Standards Guidance
Document.
B. Multiple Active Ingredient
Products
These products will not be
reregistered at this time.
However, generic data required
to continue the registration of
the active ingredient under
review, as described in the
Registration Standards Guidance
Document, will be required and
some labeling precautions may
also be required.
II. Products That Do Qualify For
The Formulator's Exemption
Only when additional restric-
tions or labeling are needed to
protect man or the environment
will these products be subject
to the Registration Standard
requirements. Affected products
will be dealt with in a variety
of ways, including but not
limited to the Label Improvement
Program and special intent
to cancel notices.
* End-use products of registrants who also produce a manufacturing-
use product will not be required to be reregistered provided that
registrant fulfills the requirements specified in the Guidance
Document for manufacturing-use product(s). Such end-use products
will be subject to the labeling changes required for products in "II"
above. If there are no manufacturing-use products registered by any
company end-use products will be required to be reregistered.
INOTE: If all registrants in "I" above fail to meet the requirements in
JI-A and B above, then the registrants in "II" lose their right to
I qualify for the formulator's exemption and become subject to the
I requirements in I-A and B»
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REGULATORY POSITION AND RATIONALE
A. INTRODUCnCN
This chapter describes the regulatory position of the Environmental Protection
Agency ("the Agency") on simazine based on an evaluation of all registered
manufacturing use products (MUP's) containing simazine as the sole active
ingredient. Future requests for registrations of substantially similar
products will be covered by this standard. Dissimilar products will
require amendments to the standard. This document provides the rationale
for the Agency's position and the criteria for registration. It also
discusses labeling requirements and tolerances that may also be pertinent
for registered end-use formulations.
"Simazine" is the accepted common name for the compound, 2-Chloro-4,6-
bis(ethylamino)-s-triazine recognized by the American National Standards
Institute. Trade and other names used for simazine include: Algae-A-Way,
Algaecide, Algidize, Algi-eater, Algi-gonf Amizine, Aquazine, Atomicide,
Cekusan, Cimacide, Framed, Gesapun, Gesatop, Primatol S, Princep,
Simadex, Simanex, and Sim-trol. The Chemical Abstracts Service (CAS)
Registry number is 122-34-9. The Office of Pesticides Program's Internal
Control Number (EPA Shaughnessy number) is 080807.
B. USE PROFILE
Simazine is a triazine compound in general use as a selective or nonselective
herbicide and algaecide. It is registered for use on many agricultural,
noncrop and aquatic sites. The major agricultural site is corn. Most
simazine is used as a preplant or preemergence herbicide on no-till or
minimum tillage corn. Almost all is applied in combination with other
herbicides, primarily atrazine. Of the total domestic simazine marketed,
approximately 36% is applied to corn, 25% to citrus (oranges, lemons, and
grapefruit), deciduous fruit and nut crops (including apples, pears, peaches,
cherries, almonds, walnuts and grapes), 20% to noncrop industrial areas,
and 19% to aquatic sites.
Registered agricultural sites include corn, citrus, deciduous fruits and
nuts, berries, vegetables, forage crops, and tree nurseries. Simazine
is also used to control algae and aquatic weeds in swimming pools, fish
and farm ponds, cooling towers, and aquaria. At higher rates, simazine
provides vegetation control on noncrcpland such as industrial sites,
highways, railroad rights-of-way and others. Corn, citrus, deciduous
fruits and nuts, and noncrop industrial uses account for most of the
simazine use in the U.S.
Simazine is applied to the soil and must be absorbed by plant roots and
translocated to the growing tips to exert an herbicidal effect. In
susceptible plant species, it acts by inhibiting photosynthesis. Simazine
controls most seedling broadleaf and grassy weeds and at higher rates
provides almost total vegetation control in noncrop areas.
Simazine is registered as a technical material at 95-99.9% active ingredient
and as a manufacturing use product containing 8.0% simazine for formulation
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of end-use products.
C. REGULATORY POSITION
Based on a review and evaluation of the available data and other relevant
information on simazine the Agency has made the following determinations:
^
1. Manufacturing-use pesticide products containing simazine, as a
sole active ingredient may be registered for sale, distribution,
formulation and use in the United States, subject to the terms
and conditions specified in this standard. Applicants having
products not conforming to the standard must apply to amend
the document so those products containing simazine may be
registered and reregistered under this standard. Mixtures
and end-use products containing simazine are not covered under
this standard.
2. Available data do not show that any of the risk criteria listed
in §162.11(a) of Title 40 of the U.S. Code of Federal Regulations
have been met or exceeded for the uses of simazine specified in
this standard.
3. The available toxicity data are insufficient to fully assess the
long-term chronic effects or the oncogenic, teratogenic, and
mutagenic potential of simazine.' In most cases the nature of
the simazine food metabolites have been adequately characterized.
The fact that the two major chloronetabolites of simazine (G-28273
and G28279) in plants are a part of some existing tolerances
indicate that these metabolites, in sane cases, are of toxicological
concern. All established tolerances for raw agricultural commodities
are expressed in terms of the parent ccmpound only, except bananas,
fish and potable water. Since chlorometabolites of simazine
are major plant residues, data pertaining to these residues are
necessary to assess the toxic properties of simazine and its
major metabolites and to determine the adequacy of the currently
established tolerances for simazine residues. Our toxicology
staff is extremely concerned with metabolites formed within
mammalian species during metabolism studies. Since previous
metabolism studies of simazine have not identified whatever
metabolites occur in food animals, additional data are necessary.
When additional studies are submitted, a complete risk assessment
will be made and the tolerance base reevaluated on the submitted
data.
4. Available data are insufficient to fully assess the environmental
fate of simazine and the exposure of humans and other nontarget
organisms to simazine. „ When additional data are submitted, a
complete environmental exposure assessment will be made.
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5. Simazine is not very toxic to nontarget insects, birds, or estuarine
and marine organisms. The wildlife and aquatic organisms tables
attached to this standard indicate the data requirements and data
gaps. A full assessment will be made when the required data
are submitted.
6. The available simazine product chemistry data are insufficient to
totally assess the chemical's characteristics. The data gaps
outlined in the product chemistry data tables are tests required
to adequately support the registration of simazine products.
7. A food additive tolerance of 0.01 part per million (ppm) has been
established for the combined residues of simazine and its metabolites,
2-amino-4-chloro-6-ethylamino-s_-triazine and 2,4-diamino-6-chloro-
s-triazine, in potable water when present as a result of application
of the herbicide to growing aquatic weeds. This tolerance will be
replaced with a designated level acceptable for drinking water when
reevaluation of the chronic data base is complete. [Refer to 47
Federal Register 25746, June 15, 1982]. [Also refer to page 8 of
this document regarding acceptable residue level of 0.03 ppm for
combined residues of simazine and its metabolites for potable water.]
8. Certain residue chemistry data are required as outlined in the
Residue Chemistry data tables. When the required studies are
submitted, a full tolerance reassessment will be made.
9. Registrants must provide or agree to develop additional data, as
specified in the tables attached to this standard, in order to
maintain existing registrations or to permit new registrations.
10. Because of the potential of simazine to contaminate groundwater,
the Agency has determined that all terrestrial uses of simazine
should be classified for restricted use and appropriate labeling
required.
D. REGULATORY RATIONALE
TThe Agency has determined thej/f oil owing:
The available data indicate that [technical simazine is a moderate
eye and dermal irritant -iToxiei^-^ategoEy—FH-X* and has low oral
and dermal toxicitiesJj(Toxicity Category TV). There are no data
available for inhalation toxicity and, therefore, a data gap exists
for this requirement.
A 21-day subacute dermal toxicity study (00057567) in rabbits at
doses up to 1 gAg produced no systemic toxicity nor any dose-
related alterations of the skin. The findings of this study
indicate a no-observed effect level of more than 1 gAg.
The two-year chronic rat feeding study showed no dose related
pathological changes. Mortality was due primarily to respiratory
infections with very few males in test and control groups surviving
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twice that of control females. Histopathologic evaluation was not
provided for animals that died during the study. Chronic toxicity
and oncogenic potential could not be determined in this study from
the feeding of simazine to rats at dosages up to 100 ppm for 104
weeks and are considered to be data gaps for this requirement.
The two-year chronic dog feeding study showed no signs of toxicity
from dosages of 15, 150 and 1,500 ppm, except net weight loss at
1,500 ppm and less weight gain at 150 ppm. Weight gain differences
did not occur during the second half of the study. Ages of individual
dogs used in the study and individual observation records were lacking.
Chronic toxicity could not be determined from this study. A data gap
exists for this requirement.
Oncogenicity Study: The available rat study does not fulfill
oncogenicity requirements and a second species (mouse) has not been
received for review.
Teratogenicity Study: No data are available for review. A data
gap exists for this requirement in two (2) species.
Reproduction Study - 3 Generation: Simazine has no adverse effects
on reproductive performance in rats at a dietary level of 100 ppm.
The findings of this study indicate a no-observed effect level
of more than 100 ppm.
Mutagencity studies are not available for review. Data gaps exist
for the entire category of mutagenicity testing.
The available metabolism studies are inadequate; therefore, a data
gap exists for a required general metabolism study in mammalian
species.
y2. Tffi available avian studies show that simazine is practically non-
toxic to birds and its uses are not expected to affect avian wildlife/}
However, an avian reproduction study on an upland gamebird species
is required since simazine persists in soil and water, is readily
taken up by plants and will persist on treated vegetation such as
seed pods. The available data is sufficient to characterize the
acute toxicity of technical simazine as slightly to moderately toxic
to freshwater fish and practically non-toxic to aquatic invertebrates.
An acute and chronic fish study on fathead minnows were conducted
with Aquazine (80% a.i.). Therefore, these requirements are considered
fulfilled for testing with a formulated product; however, a test
with a coldwater species on an 80% a.i. test material is still required.
Since simazine is persistent in water, simulated or actual field
studies may be needed for products registered for direct application
to water.
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.Available data are insufficient to fully assess the environmental
fate of simazine and exposure of humans and other nontarget organisms
to simazine^f/The following data are required to fully assess the
environmental fate and transport of, and the potential exposure to
simazine: (a) photodegradation studies on soil and in water;
(b) aerobic soil metabolism; (c) anaerobic and aerobic aquatic
metabolism; (d) leaching and adsorption/desorption; (e) terrestrial,
aquatic, forestry and long-term field dissipation studies;
(f) accumulation studies on rotational and irrigated crops.
£4. ^ie Agency has a concern about groundwater contamination by simazineT/
Data to more fully assess groundwater contamination will be ^
required on an accelerated schedule. Because of groundwater concerns,
the Agency has determined that all terrestrial uses of simazine
should be classified for restricted use and appropriate labeling
required.
5. Data to support the establishment of reentry protection standards
are not required because the Agency has determined, based on the
use patterns and available toxicity data for simazine, that the
criteria in §158.140 are not met.
6. It is not the Agency's policy to cancel or to withhold registrations
merely because data are missing or inadequate (See Sections
3(c)(2)(B) and 3(C)(7) of the FIFRA). Rather, publication of
this standard provides a mechanism for identifying data needs
for registration under the standard and allows for the upgrading
of labels during the period in which the required data are being
developed. These data will be reviewed and evaluated when they
are received and the Agency will determine at that time whether
they will affect the registration(s) of simazine.
E. CRITERIA FOR REGISTRATION UNDER THIS STANDARD
To be subject to this standard, products must meet the following
conditions:
1. Contain simazine as the sole active ingredient and,
2. • Conform to the acute toxicity limits, product composition, and
use pattern requirements listed in Section F of this document.
The applicant for registration or reregistration of products subject
to this standard must comply with all terms and conditions described
in it, including commitments to fill data gaps on a schedule agreed to
by both this Agency and the applicant. All applicants for registration
under this standard must follow the instructions contained in this
standard and complete and submit the appropriate forms within the
time specified.
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F. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Standard
Technical grade products must contain at least 95 percent simazine as
the sole active ingredient. Each manufacturing-use product formulation
proposed for registration must be fully described with an appropriate
certification of limits. In addition, the active ingredient content
found in the manufacturing-use simazine products must be substantially
similar to that in currently registered technical products. Any
manufacturing-use product not meeting these requirements will be considered
a new product and will not be registerable under this standard.
2. Acute Toxicity Limits
The Agency will consider registrations of technical grade and manufactur-
ing-use products containing simazine within acute toxicity categories
III and IV provided that the labeling of these products bears appropriate
precautionary statements.
3. Use Patterns
To be registered under this standard, manufacturing-use products contain-
ing simazine may be labeled for formulation only into end-use products
for herbicides used for the control of broadleaved and grassy weeds
in alfalfa, almonds, apples, artichokes, asparagus, avocados, bananas,
bermudagrass, blackberries, blueberries, boysenberries, cherries,
corn (all types), cranberries, filberts, grapefruits, grapes, grasses,
lemons, loganberries, macadamia nuts, olives, oranges, peaches, pears,
pecans, plums, raspberries, strawberries, sugarcane, walnuts, forage
crops, tree nurseries, Christinas tree plantings, shelter-belts, tree
plantations for timber, woody ornamentals, turfgrasses for sod, fairways,
lawns and similar areas, swimming pools, farm ponds, cooling towers,
aquaria, and nonselective weed control on noncropland such as industrial
sites, highways, and railroad rights-of-way.
G. REQUIRED LABELING
All technical grade, manufacturing-use, and end-use products containing
simazine must bear appropriate labeling as specified in 40 CFR 162.10.
Other portions of the guidance package contain specific information re-
garding label requirements.
In addition to the requirements stated in 40 CFR 162.10, the following
information must appear on the labeling:
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1. The labeling must list specific, currently registered sites
that the product is intended to be used on after manufacturing
into an end-use product or the manufacturing-use product will
be considered to be for manufacturing into end-use products
for all registered use sites.
2. Products labeled for terrestrial use(s) must be classified for
"RESTRICTED USE" and the labels must bear the following
groundwater precautionary statements:
"Simazine is known to leach through soil and has been found
in groundwater. Users are advised to apply this product
only where groundwater contamination is unlikely. Do not
apply in recharge areas of designated Sole Source Aquifers,
or in areas with well-drained soils as defined by Class A of
the Soil Conservation Service classification system which
overlay shallow aquifers or which are not protected by an
overlying impervious layer. Consult the proper state
regulatory officials in your area for information on the
location of sole source recharge areas, and the local agent
of the Soil Conservation Service for information on your
specific soil characteristics."
The above label changes must be made by December 31, 1984.
3. The labeling must incorporate the following (appropriate)
environmental precautionary statements:
Manufactur ing-Use
"Do not discharge into lakes, streams, ponds or public
water unless in accordance with an NPDES* permit. For
guidance contact your regional office of the Environ-
mental Protection Agency."
End-Use
Non-Aquatic
"Do not apply directly to water or wetlands. Do not
contaminate water by cleaning of equipment or disposal
of wastes."
Aquatic Uses
"Consult your State Fish and Game Agency before applying
to public waters. Permits may be required before treating
such waters. Do not apply directly to water except as
directed on the labeling. Do not contaminate water by
cleaning of equipment or disposal of wastes."
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Cooling Towers
"Do not discharge into lakes, streams, ponds or public
water unless in accordance with an NPDES* permit. For
guidance contact your regional office of the Environmental
Protection Agency."
*NPDES = National Pollutant Discharge Elimination System
H. TOLERANCE REASSESSMENT
In the United States, tolerances are established for residues
of simazine in or on the following raw agricultural ccmmodities
[40 CFR §180.213, 213a]:
15 ppm in Alfalfa, Alfalfa forage, Alfalfa hay, Bermuda grass,
Bermuda grass forage, Bermuda grass hay, Grass, Grass forage,
and Grass hay.
0.25 ppm in Almonds, Almond hulls, Apples, Avocados, Blackberries,
Blueberries, Boysenberries, Cherries, Corn fodder, Corn forage,
Corn (all), Corn grain. Cranberries, Currants, Dewberries,
Filberts, Grapefruit, Grapes, Lemons, Loganberries, Macadamia
nuts, Olives, Oranges, Peaches, Pears, Plums, Strawberries,
Sugarcane, and Raspberries.
10 ppm in Asparagus.
12 ppm in Fish.
0.5 ppm in Artichokes.
0.2 ppm in Bananas and Walnuts
0.1 ppm in Pecans.
0.02 ppm in Cattle fat, Cattle meat byproducts (mbyp), eggs,
Goat meat byproducts (mbyp), Goat meat, Hog fat, Hog meat
byproducts (mbyp), hog meat, horse fat, horse meat byproducts
(mbyp), Horse meat, Milk, Poultry fat, Poultry meat
byproducts (mbyp), Poultry meat, Sheep fat, Sheep meat, Sheep
meat byproducts (mbyp).
The existing tolerances for residues in or on bananas and fish are
adequate both numerically and in terms of their expression (combined
residues of simazine and its metabolites 2-chloro-4,6-diamino-s-triazine
(G-28273) and 2-amino-4-chloro-6-ethyl-amino-s-triazine (G-28279).
For potable water, an acceptable residue level of 0.03 ppm for combined
residues of simazine and its metabolites G-28273 and G-28279 should be
designated to achieve consistency with the detection limits of the method.
The remaining tolerances are set for residues of simazine per se;
however, since the chlorometabolites of simazine may constitute a
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significant portion of the residues in or on plants and animals, these
tolerances must be expressed in terms of simazine, G-28273 and G-28279.
Following submission of the chloronetabolite data requested for
representative crops, the numerical values of individual tolerances
will be reevaluated.
The current theoretical maximum residue contribution (TMPC) figure for
simazine residues in the human diet is 0.2890 mg/day (assuming a 1.5
kg diet). The effects on the TMPC of changing the tolerance expression
for all commodities to include the above metabolites cannot be assessed
until residue data including metabolites are submitted. No Acceptable
Daily Intake (ADI) or Maximum Permissible Intake (MPI) figures have been
established. Data are either lacking or insufficient to determine the
above.
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EPA Index to Pesticide Chemicals
H080807 SIMAZINE*
TYPE PESTICIDE: Herbicide; Algaecide
FORMULATIONS; Tech (95%, 97%, 98%); FI (80%); G (0.167%, 0.25%, 0.63%,
0«75%, 1%, 1.5%, 2%, 4%, 8%, 10%, 11%, 12%); P/T (0-55%, 0.6%, 0.75%,
12%); WP (0.55%, 1.1%, 45%, 80%, 90%); Impr (5%); F1C (0.88 Ib/gal,
4 Ib/gal, 3%, 3.5%, 7.5%); SC/S (1%, 20%); SC/L (0.6%); RTU (0.1%, 1%)
+ GENERAL WARNINGS AND LIMITATIONS: A translocated herbicide used to con-
' trol annual grasses and broadleaf weeds. May also be used as an algae-
cide. It should be applied before weeds emerge or following removal of
weed growth. Irrigation or rainfall is necessary to move the chemical
into the root zone of weeds. Very dry soil conditions and lack of rain-
fall following application may necessitate shallow cultivation. Reduce
dosage in proportion to band area actually treated. Where a dosage range
is given, use the lower dosage on coarse textured soil and soil low in
organic matter; use the higher dosage on fine textured soil and soil high
in organic matter.
Livestock Tolerances:
0.02 ppm in eggs and in the meat, fat and meat byproducts of cattle,
goats, hogs, horses, poultry, and sheep.
TIME REQUIRED FOR CONTROL; Not located.
PHYTOTOXICITY TO TARGET WEEDS: Not located.
PHYTOTOXICITY TO CROPS: Not located.
MODE OF ACTION: Inhibits the Hill reaction of photosynthesis.
BROADLEAF WEEDS CONTROLLED;
(apBKBGAA alyssura
@PAFACAA amaranth
(3PAAAAAB annual broadleaf weeds
@PBLAEBA balsatnapple
@PDXABBD broadleaf plantain
(apAAAAAC broadleaf weeds
(3PBVADBA bullnettle (a)
(3PBFAWBG bull thistle (a)
@PCQBIAA burclover
(3PBFAIAA burdock
@PBFAWBB Canada thistle
@PADABBA carpe tweed
@PAZAAAC chickweed
@PCQAAAB clover
(3PAZAOBB common chickweed
@PBDAEBA common lambsquarters (b)
List continued on the next page.
*Princep
2-chloro-4,6-bis(ethylamino)-s-triazine
Issued: 9-11-79
1-080807-1
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EPA Index to Pesticide Chemicals
SIMAZINE
BROADLEAF WEEDS CONTROLLED (continued)
@PEDADBA common purslane
(3PBFDHAA , dandelion
(3PBFBIBB dogfennel
@PARABAA fiddleneck
(3PBKBFBA ' field pennycress
@PBZABAA ' filaree
(3PDNABBA . fireweed
@PBDADBA fivehook bassia
@PEMAEBB florida pusley
(3PBFCXAA groundsel
(3PCOAFBA henbit
@PAZAKBA knawel
@PBDAIBA kochia
@PBDAEAB lambsquarters
@PBGAAAB morningglory
@PAZADBC mouseear chickweed
@PBKAAAC mustard
@PEWAIAA nightshade
@PBKBFAA pennycress
@PBKAWAA pepperweed
@PAAAABI pigweed
(3PBFCKBB pineappleweed
(apDXABAA plantain
@PBFCEBF prickly lettuce
(3PFMAFBB puncturevine
@PAAAABP purslane
(9PBFAEAA ragweed
(3PEDABBA redmaids rockpurslane
@PAFACBI redroot pigweed
(3PBFBFBA red tassel flower
(3PBDAKBA russian thistle
@PBKAHBA shepherdspurse
@PEAAGAD smartweed
(3PBFDCAA sowthistle
(3PBFAOBA spanishneedles
@PEUAPAA speedwell
@PAAAABD stinkweed
@PAMAHBA strangler vine
(3PBGAFBL tall morningglory
@PBKANBB tansymustard
@PBVAFBA turkey mullein
(3PDAABBB velvetleaf
@PAZAHBA white cockle
@PBKAFBE wild mustard
@PBKADAA wintercress
^PBKAWBE yellowflower pepperweed
@PBKADBB yellow rocket
(a) Hard-to-kill weeds.
(b) Use the lower dosage.
(c) Controls seedlings.
Issued: 9-11-79
(c)
(c)
(c)
(c)
(c)
(b)
(b)
(c)
(c)
(a)
(b)
(c)
(c)
(c)
(c)
1-080807-2
- 14 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
GRASSES AND OTHER MONOCOTS CONTROLLED;
@PCACKBA annual bluegrass
@PCAAAAB annual grasses
(3PCABHBB * barnyardgrass (b)
@PCACKAA bluegrass
(3PCAATBK -cheat (b)
@PCABFAA ' crabgrass (b)
(3PCAATBM , downy brorae
(3PCACEBD fall panicum
(3PCACUAA foxtail (b)(c)
(3PCABIBA goosegrass
(3PCAAAAA grasses
(3PCABZBA Italian ryegrass
(3PCABHBA junglerice
@PCABBBA orchardgrass
@PCADJBA purpletop
(3PCAACBA quackgrass
(3PCABMBB rattail fescue
(3PCAADBA red top
@PCAARAA signalgrass
^PCAAEBA silver hairgrass
@PCAATBE smooth brome
5PCAAOBB wild oat
@PAAAABC wiregrass
(3PCACEBC wifchgrass
@PCACUBD yellow foxtail
(b) Use the lower dosage.
(c) Controls seedlings.
AQUATIC WEEDS CONTROLLED;
(3PKAAAAA algae (d)
(3PKAAAAF green algae
(3PJBADAA phormidium (e)
(d) Use the lower dosage to prevent growth.
(e) Use the higher dosage.
Issued: 9-11-79
1-080807-3
- 15 -
-------
/2300100
Site, Dosage
and Formulation
(Ib a.i./A)
AGRICULTURAL CROPS
Alfalfa
$2300101
&080.0006
19001500
&090.0006
0.80-1.60
(80% WP)
0.81-1.58
(90% WP)
19001500
&080.0006
&090.0006
0.80-1.20
(80% WP)
0.81-1.17
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
15 ppra (alfalfa, forage, hay)
Do not graze for 30 days following application.
Allow 60 days between application and cutting of
hay.
General Information; Use only in areas where
frost occurs and alfalfa goes into a semi-dormant
or dormant state. Alfalfa may be growing, semi-
dormant or dormant when non-tank mix applications
are made. Do not apply on snow. Liquid fertil-
izer may replace all or part of the water used as
a carrier with the wettable powder formulations.
Do not use liquid fertilizer when the crop is ac-
tively growing. Do not use on gravelly sand,
loamy sand, soil low in organic matter or on high-
ly calcareous or alkaline soil. Apply only once
per year. Treated fields should not be rotated to
any crop except corn the growing season following
application.
AZ state label
Registration Number 010163-06399
Use limited to CO, IA, ID, KS, MI, MN, MT, ND, NE,
NV, NY, OR, SD, UT, WA, WY and the CA counties of
Del Norte, Siskiyou, Modoc, Shasta, Lassen,
Plumas, Sierra and Nevada. Broadcast. Use on
crops established for at least 1 year. Apply in
the fall after the last cutting, prior to perma-
nently frozen ground conditions. Apply in a mini-
mum of 15 gallons of water per acre by ground, or
in a minimum of 2.5 gallons by air.
Use limited to CT, DE, IL, IN, KY, MA, MD, ME, MO,
NH, NJ, OH, PA, RI, VA, VT and WV. Broadcast.
Use on crops established for at least 1 year. Ap-
ply in the fall after the last cutting, prior to
permanently frozen ground conditions. Apply in a
minimum of 15 gallons of water per acre by ground,
or in a minimum of 2.5 gallons by air.
Issued: 9-11-79
1-080807-4
- 16 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
19001500
&080.0006
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
, Alfalfa (continued)
0.80
(80% WP)
/
0.81
(90% WP)
Tolerance, Use, Limitations
&000.1704
&000.2504
&000.1704
&000.2504
$230011S
&080.0006
19900300
19001500
&090.0006
0.75-1.25
(0.167% G)
(0.25% G)
0.75-0.83
(0.167% G)
(0.25% G)
0.80-1.60
(80% WP)
0.81-1.58
(90% WP)
Use limited to the Northeastern United States.
Broadcast. Use on crops established for less than
1 year. Alfalfa which has been seeded in the
spring before June 1 and has become established
can be treated in the fall after the last cutting,
prior to permanently frozen ground conditions.
Apply in a minimum of 15 gallons of water per acre
by ground, or in a minimum of 2.5 gallons by air.
Use limited to the Northeastern and North Central
States. Broadcast. Use on crops established for
at least 1 year. Apply in the fall, prior to per-
manently frozen ground conditions.
Use limited to the Northeastern and North Central
States. Broadcast. Use on crops established for
less than 1 year. Alfalfa which has been seeded
in the spring before June 1 and has become estab-
lished can be treated in the fall, prior to perma-
nently frozen ground conditions.
Use limited to CO, ID, MT, NV, OR, UT, WY and the
CA counties of Del Norte, Lassen, Modoc, Nevada,
Plumas, Shasta, Sierra and Siskiyou. Dormant.
Broadcast. Tank mix with paraquat dichloride.
Apply to established alfalfa after the last fall
cutting, when crop is dormant, and before spring
growth begins. Do not apply if regrowth following
the last fall cutting is more than 2 inches tall.
Alfalfa foliage present will be burned. Apply in
20 to 100 gallons of water per acre by ground, or
in 5 to 10 gallons by air.
Issued: 9-11-79
1-080807-5
- 17 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
/2802900
Alfalfa-Orchardgrass
Mixture
$2802915
&080.0006
19001500
&090.0006
&000.1704
&000.2504
/0300100
0.80
(80% WP)
0.81
(90% WP)
0.75-0.84
(0.167% G)
0.75-0.81
(0.25% G)
Almond
15 ppm (alfalfa, forage, hay)
15 ppm (grass, forage, hay)
Do not graze for 30 days following application.
Allow 60 days between application and cutting for
hay.
General Information; Use only in areas where
frost occurs and alfalfa goes into a semi-dormant
or dormant state. Alfalfa must be dormant when
applications are made. Do not apply on snow.
Liquid fertilizer may replace all or part of the
water used as a carrier with the wettable powder
formulations. Do not use liquid fertilizer when
the crop is actively growing. Do not use on grav-
elly sand, loamy sand, soil low in organic matter
or on highly calcareous or alkaline soil. Apply
only once per year. Treated fields should not be
rotated to any crop except corn the growing season
following application.
Use limited to the Northeastern States. Dormant.
Broadcast. Use on crops established for at least
1 year. Apply in the fall after crop has gone
dormant. Apply in a minimum of 15 gallons of
water per acre by ground, or in a minimum of 2.5
gallons by air.
Use limited to the Northeastern and North Central
States. Dormant. Broadcast. Use on crops estab-
lished for at least 1 year. Apply in the fall
after crop has gone dormant.
0.25 ppm (almonds, hulls)
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 3 years. Make only 1
application per year. Do not use around mission
variety propagated on plum rootstocks. Do not use
on gravelly sand, loamy sand or on soil with less
than 1 percent organic matter. Do not use where
water will accumulate. Do not replant almonds or
peaches in treated soil.
CA state label
Registration Number 000100-04283
Issued: 9-11-79
1-080807-6
- 18 -
-------
EPA Index to Pesticide Chemicals
$0300102
&080.0006
19900300
&090.0006
/0400100
$0400102
&090.0006
19900300
&080.0006
&104.0014'
&004.0004
/0400100
$0400116
&004.0004
F
&045.0006
Site, Dosage
and Formulation
(Ib a.i./A)
Almond (continued)
• 1.00-2.00
' (80% WP)
0.99-1.98
(90% WP)
Apple
2.16-3.96
(90% WP)
2.00-4.00
(80% WP)
(4 Ib/gal F1C)
2.00-4.00
(4% G)
6.00-8.00
(4% G)
3.15-3.43
(45% WP)
SIMAZINE
Tolerance, Use, Limitations
Use limited to CA. Directed spray. Band appli-
cation in the row. Apply a 2 to 4 foot band on
each side of the tree row. Apply in 20 to 40 gal-
lons of water per acre. Apply before weeds emerge
in late fall or early winter. May be tank mixed
with paraquat dichloride. Apply the tank mix in
50 to 200 gallons of water per acre.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Make only 1 ap-
plication per year.
AZ state label
Registration Number 010163-06399
Directed spray. Broadcast or band. Apply in 20
to 40 gallons of water per acre. The wettable
powder formulations may be tank mixed with para-
quat dichloride.
Directed application to orchard floor.
the spring before weeds emerge.
Apply in
Apple"(non-bearing) N.F.
Directed application to orchard floor. Apply in
early spring during the dormant season^ Apply
around trees established for at least 1 year.
Directed spray. Broadcast or band. Apply in the
spring after weeds emerge, but before fruit begins
to form. Apply in 100 gallons of water per acre.
Formulated with amitrole.
Issued: 9-11-79
1-080807-7
- 19 -
-------
/1301800
$1301802
&080.0006
&090.0006
/1600200
$1600202
&080.0006
&090.0006
/2800000
$2800002
&002.0004
&080.0006
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
* Artichoke (Globe)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Asparagus
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Avocado
4.00
(2% G)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
0.5 ppm
AZ state label
Registration Number 010163-06399
Directed spray. Apply after last fall tillage.
Do not apply to sandy soil. Apply once a year.
10 ppm
AZ state label
Registration Number 010163-06399
Directed spray. Apply once a year, either after
discing in the spring before weeds emerge, or fol-
lowing harvest, after removal of existing weed
growth. Spring application must be made at least
3 days before first cutting. Use only where as-
paragus has been established for 1 year. In OR
and WA, do not use on sandy soils, and do not
allow irrigation water to stand or form pools.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply around trees
established for at least 1 year. Make only 1 ap-
plication per year. Do not use on coarse or sandy
soils.
CA state label
Registration Number 011656-05903
Use limited to CA. Directed application to or-
chard floor. Apply after the orchard has been
laid up in final form (late fall or early winter),
prior to or immediately following weed seed germi-
nation, but prior to emergence. Avoid packing
fruit for 10 days. Do not apply to trees that
have been subjected to freezing within 1 year.
Use limited to CA. Directed spray. Broadcast or
band. Apply after final preparation of the or-
ch ard.
Issued: 9-11-79
1-080807-8
- 20 -
-------
/2201700
$2201702
&080.0006
&090.0006
$2201701
&080.0006
19001500
&090.0006
/0100200
$0100202
&090.0006
&004.0004
&080.0006
Site, Dosage
and Formulation
(Ib a.i./A)
. * Bermudagrass
0.80-3.20
(80% WP)
0.81-3.15
(90% WP)
0.80-3.20
(80% WP)
0.81-3.15
(90% WP)
Blackberry
1.98-3.96
(90% WP)
2.00-4.00
(4% G)
(80% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
15 ppm (bermudagrass, forage, hay)
Do not graze for 30 days after application of 0.8
to 2.4 pounds active ingredient per acre, or for
50 days after application of 3.15 pounds or more
active ingredient per acre. Do not cut hay for 60
days after application of 0.8 to 2.4 pounds active
ingredient per acre, or for more than 90 days
after 3.15 pounds or more active ingredient per
acre.
General Information; Do not use in NM and the
High Plains of TX.
AZ state label
Registration Number 010163-06399
Preemergence. Broadcast. Apply shortly after
sprigging. Apply in a minimum of 15 gallons of
water per acre.
Postemergence. Broadcast. Apply from fall to
spring depending on the weed problem, but before
weed emergence. Apply in a minimum of 15 gallons
of water per acre. For aerial application, use a
minimum of 1 gallon of water for each 1 to 1.5
pounds of wettable powder. Do not apply within 7
days after cutting.
0.25 ppm
Do not apply when fruit is present.
General Information: Do not allow spray to con-
Use one-half the dosage
Apply the
tact foliage or stems.
on plantings less than 6 months old.
wettable powders in a minimum of 40 gallons of
water per acre.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Apply in the spring before
buds break and weeds emerge.
Issued: 9-11-79
1-080807-9
- 21 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use> Limitations
&080.0006
&090.0006
&004.0004
&080.0006
&090.0006
/0100900
$0100902
S0100202
/0100300
Blackberry (continued)
2.00
(80% WP)
1.98
(90% WP)
3.92-4.00
(4% G)
4.00
(80% WP)
3.96
(90% WP)
Blueberry
Boysenberry
Directed spray. Split application. Apply once
in the spring and once in the fall.
Directed application. Quackgrass control. Apply
once in the fall, or apply as a split application
using one-half the dosage in the fall and one-
half the dosage in the spring.
$0100302
S0100202
0.25 ppm
Do not apply when fruit is present.
General Information; Do not allow spray to con-
tact foliage or stems. Use one-half the dosage
on plantings less than 6 months old.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Blackberry for use and limitation information.
0.25 ppm
Do not apply when fruit is present.
General Information: Do not allow spray to con-
tact foliage or stems. Use one-half the dosage
on plantings less than 6 months old.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Blackberry for use and limitation information.
Issued: 9-11-79
1-080807-10
- 22 -
-------
Site, Dosage
and Formulation
/0500200
$0500202
&080.0006
19900300
&090.0006
$0500202
&080.0006
&090.0006
/0500200
$0500216
&004.0004
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Make only 1 ap-
plication per year.
AZ state label
Registration Number 010163-06399
(sour)
2.00-4.00
(80% WP)
2.16-3.96
(90% WP)
(sweet)
1.60-4.00
(80% WP)
1.58-3.96
(90% WP)
Cherry (non-bearing)
(sour)
6.00-8.00
(4% G)
Use limited to MI and WA. Directed spray. Apply
in 20 to 40 gallons of water per acre. May be
tank mixed with paraquat dichloride.
Use limited to MO and states east of the Missis-
sippi River (except TN). Directed spray. Apply
in late fall to early spring prior to weed erner-.
gence. Apply in 20 to 40 gallons of water per
acre. Do not apply to sandy soils.
N.F.
General Information; Do not allow spray to con-
tact foliage or stems. Apply to orchards estab-
lished for at least 1 year. Make only 1 applica-
tion per year.
Dormant. Directed application to orchard floor.
Apply in early spring when trees are still dor-
mant.
Issued: 9-11-79
1-080807-11
- 23 -
-------
/2800500
Site, Dosage
and Formulation
(Ib a.i./A)
Corn
$2800502
5,090.0006
&080.0006
&104.0014
19001500
&090.0006
&080.0006
&104.0014
2.97-3.96
(90% WP)
3.00-4.00
(80% WP)
(4 Ib/gal F1C)
1.98-3.96
(90% WP)
2.00-4.00
(80% WP)
(4 Ib/gal F1C)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
0.25 ppm (forage, fodder, grain and fresh corn,
including sweet corn (kernels plus cob with husks
removed))
General Information: Do not apply more than 4
pounds active ingredient per acre to corn in 1
year. Treated land should not be planted with
any crop except corn until the following year.
After harvest of a treated crop, plow and thor-
oughly till the soil in the fall or spring to
minimize possible injury to spring seeded rota-
tional crops. If more than 3 pounds active ingre-
dient per acre is used, a crop of untreated corn
should precede the next rotational crop. In the
high plains and intermountain areas of the West
(including central and western KS, western NB,
western OK and the Panhandle of TX) where rainfall
is sparse and erratic or where irrigation is re-
quired, use the product to control weeds in corn
only when corn is to follow corn, or a crop of un-
treated corn is to precede another rotational
crop. In western MN and eastern parts of ND, SD,
NB and KS, do not plant soybeans following corn
treated with more than 2 pounds active ingredient
per acre. Do not plant sugar beets, tobacco,
vegetables (including dry beans), spring seeded
small grains, or small seeded legumes and grasses,
the year after application. Liquid fertilizer may
replace all or part of the water as a carrier. Do
not use liquid fertilizers when making postemer-
gence applications.
AZ state label
Registration Number 010163-06399
Preplant. Broadcast. Quackgrass control. Apply
in the fall. Plow 2 to 3 weeks later. If soil
erosion is a problem, delay plowing until spring.
Do not plant any crop except corn in the spring.
Do not graze treated areas.
Preplant or preemergence. Broadcast or band. Ap-
ply before, during or after planting, but before
crop and weeds emerge. Apply in 10 to 40 gallons
of water per acre after plowing; either before,
during or after final seedbed preparation. Avoid
deep incorporation. Broadcast applications may be
aerially applied.
Issued: 9-11-79
1-080807-12
- 24 -
-------
19900300
&080.0006
&090.0006
&104.00U
$2800541
&080.0006
19900300
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
Corn (continued)
1.00-1.44
' (80% WP)
1.00-1.46
(90% WP)
1.00-1.50
(4 Ib/gal F1C)
2.00-3.00
(80% WP)
1.98-2.97
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Preplant or preemergence. Broadcast or band.
Tank mix with atrazine. Apply before, during or
after planting, but before crop and weeds emerge.
Apply in 10 to 40 gallons of water per acre after
plowing, either before, during or after final
seedbed preparation. Avoid deep incorporation.
Preemergence. Broadcast. Tank mix with paraquat
dichloride for use in no-till or minimum-till sys-
tems where corn is seeded directly into a cover
crop, established sod, or previous crop residue.
Apply in 20 to 60 gallons of water per acre before
or after planting, but before corn emerges. Use
with a surfactant.
/0101000
Cranberry
$0101002
&090.0006
&004.0004
&080.0006
&090.0006
&004.0004
&080.0006
1.98
(90% WP)
2.00
(4% G)
(80% WP)
1.98-3.96
(90% WP)
2.00-4.00
(4% G)
(80% WP)
0.25 ppm
General Information; Do not allow spray to con-
tact foliage or stems. Apply to plots established
for at least 1 year. Make only 1 application per
year.
CA state label
Registration Number 005481-03858
Directed application. Apply before spring growth
begins, prior to weed emergence. Apply the wet-
table powders in 20 to 40 gallons of water per
acre.
Use limited to MA. Directed application. Apply
before spring growth begins, prior to weed emer-
gence, or in the fall after harvest. Apply the
wettable powders in 20 to 40 gallons of water per
acre.
Issued: 9-11-79
1-080807-13
- 25 -
-------
/0300500
$0300502
&080.0006
19900300
&090.0006
/0200200
$0200202
&002.0004
Site, Dosage
and Formulation
(Ib a.i./A)
* Filbert
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Grapefruit
4.00
(2% G)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Do not use on
gravel, sand or loamy sand soil. Do not apply
when nuts are on the ground.
Directed spray. Apply once in the fall, or make a
split application using the lower dosage in the
fall and again in the spring. Apply in 20 to 40
gallons of water per acre. May be tank mixed with
paraquat dichloride.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Make only 1 ap-
plication per year, except where split applica-
tions are recommended. For band applications or
spot applications, reduce dosage in proportion to
area actually treated. Do not use in nurseries.
Do not apply around trees under stress from freeze
damage for 1 year after freezing.
CA state labels
Registration Number 000100-04283
Registration Number 005481-03858
FL state label
Registration Number 000100-04296
Use limited to CA (except Palo Verde, Imperial and
Coachella Valleys). Directed application to grove
floor. Apply after the grove has been laid up in
final form in late fall or early winter, prior to
or immediately following weed seed germination,
but prior to weed emergence. Do not use on coarse
textured soils.
&090.0006
&080.0006
&104.0014
&004.0004
1.98-3.96
(90% WP)
2.00-4.00
(80% WP)
(4 Ib/gal F1C)
6.40-9.60
(4% G)
Use limited to CA (except Palo Verde, Imperial and
Coachella Valleys). Directed spray. Broadcast or
band. Apply in 20 to 40 gallons of water per
acre.
Use limited to FL. Directed application to grove
floor. Apply in the sping (March or April), prior
to weed emergence. Repeat annually.
Issued: 9-11-79
1-080807-14
- 26 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
Site, Dosage
and Formulation
(Ib a.i./A)
* Grapefruit (continued)
. 6.39-9.54
&090.0006 ' (90% WP)
6.40-9.60
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
19900300 3.15-3.20
&090.0006 (90% WP)
3.20
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
19900300 6.40-9.60
&080.0006 (80% WP)
6.39-9.54
&090.0006 (90% WP)
19900300 3.96
&090.0006 (90% WP)
4.00
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
4.00-5.00
&004.0004 (4% G)
3.96-4.77
&080.0006 (80% WP)
&090.0006 (90% WP)
&104.0014 (4 Ib/gal F1C)
19900300 3.15-3.96
&090.0006 (90% WP)
Tolerance, Use, Limitations
Use limited to FL. Directed spray. Broadcast or
band. Apply in the spring. For milkweed vine
control, use 8 to 9.6 pounds active, ingredient per
acre and apply prior to emergence, or before vines
are 12 inches tall. Apply in 20 to 40 gallons of
water per acre.
Use limited to FL (bedded areas). Directed spray.
Broadcast or band. Tank mix with ametryn. For
control of balsamapple vine, apply prior to emer-
gence, or to vines up to 12 inches tall. Apply in
a minimum of 40 gallons of water per acre.
Use limited to FL (ridge areas). Directed spray.
Broadcast or band. Tank mix with paraquat dichlo-
ride. Apply in 50 to 200 gallons of water per
acre in the spring.
Use limited to FL (ridge areas). Directed spray.
Broadcast or band. Tank mix with ametryn. For
control of milkweed vine, apply prior to emer-
gence, or to vines up to 24 inches tall. Apply in
a minimum of 40 gallons of water per acre.
Use limited to TX. Directed application to grove
floor. Apply in the spring.
Use limited to TX. Directed spray. Broadcast or
band. Apply in 20 to 40 gallons of water per acre
in the spring.
3.20-4.00
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
Use limited to TX. Directed spray. Broadcast or
band. Tank mix with ametryn. Use the higher dos-
age for longer residual control. Apply in a mini-
mum of 40 gallons of water per acre.
Issued: 9-11-79
1-080807-15
- 27 -
-------
/0101400
$0101402
&090.0006
19900300
&080.0006
&104.0015
/0200400
$0200402
&090.0006
&080.0006
&104.0014
&002.0004
Site, Dosage
and Formulation
(Ib a.i./A)
* Grapes
1.98-4.77
(90% WP)
2.00-4.80
(80% WP)
(4 Ib/gal SC/L)
Lemon
1.58
(90% WP)
1.60
(80% WP)
(4 Ib/gal F1C)
4.00
(2% G)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Do not use in vine-
yards established for less than 3 years. Apply
only once per year.
AZ state label
Registration Number 010163-06399
Use limited to CA, MI and NY. Directed spray.
Broadcast or band. Apply in 20 to 40 gallons of
water per acre between harvest and early spring.
The wettable powders may be tank mixed with para-
quat dichloride.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply to groves
established for at least 1 year. Make only 1 ap-
plication per year except where split applications
are recommended. Do not use in nurseries. Do not
apply to bedded fruit. Do not apply around trees
under stress from freeze damage for 1 year after
freezing.
AZ state label
Registration Number 010163-06399
CA state labels
Registration Number 000100-04283
Registration Number 011656-05903
FL state label
Registration Number 000100-04296
Use limited to AZ. Directed spray. Split appli-
cation. Broadcast or band. Apply once in the
spring and once in the fall. Apply in 20 to 40
gallons of water per acre.
Use limited to CA (except Palo Verde, Imperial and
Coachella Valleys). Directed application to grove
floor. Apply after the grove has been laid up in
final form in late fall or early winter, prior to
or immediately following weed seed germination,
but prior to weed emergence. Do not use on coarse
textured soils.
Issued: 9-11-79
1-080807-16
- 28 -
-------
19900300
&090.0006
&080.0006
&104.0014
/0100500
$0100502
S0100202
/0300700
$0300702
&080.0006
&090.0006
/0600900
Site, Dosage
and Formulation
(Ib a.i./A)
* Lemon (continued)
1.98-3.96
t (90% WP)
2.00-4.00
(80% WP)
(4 Ib/gal FIG)
Loganberry
Macadamia Nut
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Olive
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Use limited to CA (except Palo Verde, Coachella or
Imperial Valleys). Directed spray. Broadcast or
band. Apply as a single application or as a split
application using the lower dosage in the spring
and again in the fall. Apply in 20 to 40 gallons
of water per acre. The wettable powder formula-
tions may be tank mixed with paraquat dichloride.
0.25 ppm
General Information; Do not allow spray to con-
tact foliage or stems. Apply to plots established
for at least 1 year. Make only 1 application per
year.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Blackberry for use and limitation information.
0.25 ppm
General Information: Do not allow spray to con-
tact nuts, foliage or stems. Apply to orchards
established for at least 1 year. Do not use on
sand or gravelly soil.
AZ state label
Registration Number 010163-06399
Directed spray. Broadcast or band. Apply before
harvest and prior to weed emergence. Repeat as
necessary. Apply in 50 gallons of water per acre.
Do not apply when nuts are on the ground.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply to groves
established for at least 1 year. Make only 1
application per year.
AZ state label
Registration Number 010163-06399
Issued: 9-11-79
1-080807-17
- 29 -
-------
$0600902
&080.0006
&090.0006
/0200600
$0200602
&090.0006
&080.000*
&104.0014
&002.0004
19900300
&090.0006
&080.0006
&104.0014
Site, Dosage
and Formulation
(Ib a.i./A)
Olive (continued)
2.00-4.00
' (80% WP)
1.98-3.96
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
1.58
(90% WP)
1.60
(80% WP)
(4 Ib/gal F1C)
4.00
(2% G)
1.98-3.96
(90% WP)
2.00-4.00
(80% WP)
(4 Ib/gal F1C)
Directed spray. Broadcast or band. Apply follow-
ing grove preparation in the fall. Repeat annual-
ly in midwinter. Apply in 20 to 40 gallons of
water per acre.
0.25 ppm
General Information; Do not allow spray to con-
tact fruit, foliage or stems. Apply to groves
established for at least 1 year. Make only 1 ap-
plication per year except where split applications
are recommended. Do not use in nurseries. Do not
apply around trees under stress from freeze damage
for 1 year after freezing.
AZ state label
Registration Number 010163-06399
CA state labels
Registration Number 000100-04283
Registration Number 005481-03858
Registration Number 011656-05903
FL state label
Registration Number 000100-04296
Use limited to AZ. Directed spray. Split appli-
cation. Broadcast or band. Apply once in the
spring and again in the fall. Apply in 20 to 40
gallons of water per acre.
Use limited to CA (except Palo Verde, Imperial and
Coachella Valleys). Directed application to grove
floor. Apply after the grove has been laid up in
final form in late fall or early winter, prior to
or immediately following weed seed germination,
but prior to weed emergence. Do not use on coarse
textured soils.
Use limited to CA (except Palo Verde, Imperial and
Coachella Valleys). Directed spray. Broadcast or
band. Apply as a single application or as a split
application, using the lower dosage in the spring
and again in the fall. Apply in 20 to 40 gallons
of water per acre. The wettable powder formula-
tions may be tank mixed with paraquat dichloride.
Issued: 9-11-79
1-080807-18
- 30 -
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and Formulation
(Ib a.i./A)
* Orange (continued)
6.40-9.60
&004.0004 , (4% G)
6.39-9.54
&090.0006 (90% WP)
6.40-9.60
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
19900300 3.15
&090.0006 (90% WP)
3.20
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
19900300 3.20
&080.0006 (80% WP)
3.15
&090.000S (90% WP)
19900300 3.96
&090.0006 (90% WP)
4.00
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
19900300 6.40-9.60
&080.0006 (80% WP)
6.39-9.54
&090.0006 (90% WP)
4.00-5.00
&004.0004 (4% G)
3.96-4.77
&090.0006 (90% WP)
4.00-8.00
&080.00n6 (80% WP)
&104.0014 (4 Ib/gal FlC)
SIMAZINE
Tolerance, Use, Limitations
Use limited to FL. Directed application to grove
floor. Apply in the spring (March or April),
prior to weed emergence. Repeat annually.
Use limited to FL. Directed spray. Broadcast or
band. Apply in the spring. For milkweed vine
control, use 8 to 9.6 pounds active ingredient per
acre and apply prior to emergence, or before vines
are 12 inches tall. Apply in 20 to 40 gallons of
water per acre.
Use limited to FL (bedded areas). Directed spray.
Broadcast or band. Tank mix with ametryn. For
control of balsamapple vine, apply prior to emer-
gence, or to vines up to 12 inches tall. Apply in
a minimum of 40 gallons of water per acre.
Use limited to FL (bedded areas). Directed spray.
Broadcast or band. Tank mix with paraquat dichlo-
ride. Apply in 50 to 200 gallons of water per
acre in the spring.
Use limited to FL (ridge areas). Directed spray.
Broadcast or band. Tank mix with ametryn. For
control of milkweed vine, apply prior to emer-
gence, or to vines up to 24 inches tall. Apply in
a minimum of 40 gallons of water per acre.
Use limited to FL (ridge areas). Directed spray.
Broadcast or band. Tank mix with paraquat dichlo-
ride. Apply in 50 to 200 gallons of water per
acre in the spring.
Use limited to TX. Directed application to grove
floor. Apply in the spring.
Use limited to TX. Directed spray. Broadcast or
band. Apply in 20 to 40 gallons of water per acre
in the spring.
Issued: 9-11-79
1-080807-19
- 31 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
* Orange (continued)
19900300 . 3.15-3.96
&090.0006 , (90% WP)
3.20-4.00
&080.0006 (80% WP)
&104.0014 (4 Ib/gal F1C)
/2202800 Orchardgra3s (seed
crop)
$2202804 2.00
&080.0006 (80% WP)
1.98
&090.0006 (90% WP)
/0500400 Peach
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Use limited to TX. Directed spray. Broadcast or
band. Tank mix with ametryn. Use the higher dos-
age for longer residual control. Apply in a mini-
mum of 40 gallons of water per acre.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Broadcast. Apply in the fall as soon as
fall rains begin. Apply in a minimum of 15 gal-
lons of water per acre. Use only on grasses from
which at least 1 seed crop has been cut.
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 3 years. Make only 1 ap-
plication per year. Do not replant peaches or al-
monds in treated soil.
$0500402
&080.0006
19900300
&090.0006
19900300
&080.0006
&090.0006
1.00-2.00
(80% WP)
0.99-1.98
(90% WP)
1.60-4.00
(80% WP)
1.58-3.96
(90% WP)
CA state label
Registration Number 000100-04283
Use limited to CA. Directed spray. Band applica-
tion. Apply a 2 to 4 foot band on each side of
the tree row before weeds emerge in late fall or
early winter. Apply in 20 to 40 gallons of water
per acre. May be tank mixed with paraquat dichlo-
ride. Apply the tank mix in 50 to 200 gallons of
water per acre.
Use limited to AK, LA, MO, OK, TX and states east
of the Mississippi River. Directed spray. Broad-
cast or band. Tank mix with paraquat dichloride.
Apply in 50 to 200 gallons of water per acre. Do
not use on sand or gravelly soils.
Issued: 9-11-79
1-080807-20
- 32 -
-------
EPA Index to Pesticide Chemicals
/0500400
$0*00416
&004.0004
/0400300
$0400302
&080.0006
19900300
&090.0006
/0400300
$0400316
&004.0004
/0300800
$0300802
&08f>.0006
19900300
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
* Peach (non-bearing)
6.00-8.00
, (4% G)
Pear
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
6.00-8.00
(4% G)
Pecan
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
SIMAZINE
Tolerance, Use, Limitations
N.F.
Directed application to orchard floor. Apply in
February or March, when trees are still dormant.
Apply around trees established for at least 1
year.
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Make only 1 ap-
plication per year.
AZ state label
Registration Number 010163-06399
Directed spray. Broadcast or band. Apply in 20
to 40 gallons of water per acre. Do not apply to
sandy soils. May be tank mixed with paraquat di-
chloride. Apply the tank mix in 50 to 200 gallons
of water per acre.
Pear (non-bearing) N.F.
Directed application to orchard floor. Apply in
February or March, when trees are still dormant.
Apply around trees established for at least 1
year.
0 • 1 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 2 years. Make only 1 ap-
plication per year. Do not use on sand or loamy
sand. Do not apply when nuts are on the ground.
Directed spray. Broadcast or band. Apply before
weeds emerge in the spring. Apply in 20 to 40
gallons of water per acre. Do not use west of the
Pecos River in TX or NM. May be tank mixed with
paraquat dichloride.
Issued: 9-11-79
1-080807-21
- 33 -
-------
7220^500
$2203504
S2202804
/0500500
$0500502
&080.0006
19900300
&090.0006
/0100600
$0100602
S0100202
/0101600
$0101615
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
* Perennial Ryegrass
(seed crop)
Plum
1.60-4.00
(80% WP)
1.58-3.96
(90% WP)
Raspberry
Strawberry
0.99
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to Orchardgrass (seed crop) for use
and limitation information.
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Apply to orchards
established for at least 1 year. Make only 1
application per year.
Use limited to MO and states east of the Missis-
sippi River (except TN). Directed spray. Broad-
cast or band. Apply in late fall to early spring,
prior to weed emergence. Do not apply to sandy
soils. May be tank mixed with paraquat dichlo-
ride. Apply the tank mix in 50 to 200 gallons of
water per acre.
0.25 ppm
General Information: Do not allow spray to con-
tact fruit, foliage or stems. Make only 1 appli-
cation per year except where split applications
are recommended.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Blackberry for use and limitation information.
0.25 ppm
Use limited to OR and WA. Postharvest. Broad-
cast. Apply from early October through November
where overhead irrigation is not available. Apply
after harvest at the time of bed renovation when
overhead irrigation is available. Limit overhead
irrigation to 0.5 inch immediately after applica-
tion. Do not apply within 4 months after trans-
planting. Make only 1 application per growing
season. Do not use on sandy soils.
Issued: 9-11-79
1-080807-22
- 34 -
-------
EPA Index to Pesticide Chemicals
/2500300
$2500302
&080.0006
&090.0006
$2500301
&080.0006
&090.0006
/2204300
$2204304
S2202804
Site, Dosage
and Formulation
(Ib a.i./A)
Sugarcane
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Tall Fescue (seed
SIMAZINE
Tolerance, Use, Limitations
0.25 ppm
Do not graze treated areas.
AZ state label
Registration Number 010163-06399
Preemergence. Broadcast. Apply at planting or
after harvest if ratoon crop is to be grown, but
before weeds or sugarcane emerge.
Postemergence. Broadcast or band. Use to provide
continuing control of germinating weeds. Do not
make more than 1 broadcast application over the
crop. Do not make more than 2 interline directed
applications. Do not apply after close-in. Total
application should not exceed 10 pounds active in-
gredient per acre per crop cycle.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days follow-
ing application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to Orchardgrass (seed crop) for use
and limitation information.
/0300900
Walnut
$0300902
&080.0006
&090.0006
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
0.25 ppm
General Information: Do not allow spray to con-
tact nuts, foliage or stems. Apply around trees
established for at least 1 year. Make only 1
application per year. Leveling and furrowing
operations after application will reduce effec-
tiveness. Do not apply to sandy soil. Do not
apply when nuts are on the ground.
AZ state label
Registration Number 010163-06399
Directed spray. Broadcast or band.
to 40 gallons of water per acre.
Apply in 20
Issued: 9-11-79
1-080807-23
- 35 -
-------
19900300
&OS0.0006
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
* Walnut (continued)
2.00-4.00
< (80% WP)
1.98-3.96
(•90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Use limited to CA. Directed spray. Broadcast or
band. Tank mix with paraquat dichloride.
/6600000
$6600002
&004.0004
19900300
19001500
&090.0006
&080.0006
&104.0014
AGRICULTURAL PREMISES
General Warnings and Limitations; Do not use on land to be cropped, near
desirable plants or in greenhouses.
Uncultivated Agricul- N.F.
tural Areas General Information:
10.00-40.00
(4% G)
4.77-39.66
(90% WP)
4.80-40.00
(80% WP)
(4 Ib/gal F1C)
Uncultivated agricultural
areas include areas around buildings, silos,
barns, equipment and fuel storage areas, fence-
rows, roadsides, and lanes. Use the higher dos-
ages for perennial weed control, for longer resid-
ual control, and in areas with high rainfall or a
long growing season.
AZ state labels
Registration Number 010163-06399
Registration Number 038059-09682
Formulated with sodium metaborate, sodium
chlorate, and prometone.
CA state labels
Registration Number 005481-03858
Registration Number 006973-04607
Broadcast. Apply before weed emergence or follow-
ing weed removal. Apply the wettable powder and
flowable concentrates in a minimum of 1 gallon of
water per 0.8 pound active ingredient. If weed
growth has begun prior to application and removal
is not possible, tank mix with a contact or trans-
located herbicide. Aerial applications may be
made where practical.
Issued: 9-11-79
1-080807-24
- 36 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index Co Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
- Uncultivated Agricultural Areas (continued)
F /.'. v
&010.0004
&000.7505
&045.0006
15.00-22.50
(10% G)
1.63-6.53
(0.75% P/T)
9.00
(45% WP)
Broadcast. Apply just before or after weed growth
begins, usually in the spring or early summer.
Cut and remove tall weeds 2 weeks before appli-
cation. Apply the wettable powder in 100 gallons
of water per acre.
Formulated with amitrole; karbutilate; or sodium
metaborate, sodium chlorate, and prometone.
/3514100
$3^14102
&045.0006
F
/3501900
$3501902
&004.0004
&080.0006
&090.0006
ORNAMENTALS
American Beech
3.15
(45% WP)
American Elm
&004.0004
2.00-3.05
(4% G)
2.00-3.00
(80% WP)
1.98-3.06
(90% WP)
1.25-1.75 Ib
product/1,000
sq.ft
(4% G)
N.F.
Directed spray. Treat plants that have been
established for at least 1 year. Apply in the
spring or early summer before weeds mature. Cut
and remove tall weeds 2 weeks before application.
Apply in 100 gallons of water per acre. Repeat
if necessary.
Formulated with amitrole.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Apply prior to weed emer-
gence in the fall or spring, at least 1 year after
transplanting. Do not use on seedbeds or cutting
beds. Do not apply more than once per year. Ap-
ply the wettable powders in a minimum of 25 gal-
lons of water per acre.
Issued: 9-11-79
1-080807-25
- 37 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
^American Elm (continued)
&045.0006
3.15
(45% WP)
/3502100
$3502102
S3501902
/3502400
$3502402 .
&004.0004
&080.0006
&090.0006
&004.0004
/3502600
Arborvitae
Austrian Pine
2.00-3.05
(4% G)
2.00-3.00
(80% WP)
1.98-3.06
(90% WP)
1.25-1.75 Ib
product/I,000
sq. ft
(4% G)
Balsam Fir
Directed spray. Treat plants that have been
established for at least 1 year. Apply in the
spring or early summer before weeds mature. Cut
and remove tall weeds 2 weeks before application.
Apply in 100 gallons of water per acre. Repeat
if necessary.
Formulated with amitrole.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Apply prior to weed emer-
gence in the fall or spring, at least 1 year after
transplanting. Do not use on seedbecs or cutting
beds. Do not apply more than once per year. Ap-
ply the wettable powders in a minimum of 25 gal-
lons of water per acre.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Issued: 9-11-79
1-080807-26
- 38 -
-------
$3502602
S3501902
/3402500
$3502502
S3502402
/3302500
$3302504
S2202804
/3301700
$3301715
&000.6304
/3532500
$3532502
&080.0006
&090.0006
/3503300
Site, Dosage
and Formulation
(Ib a.i./A)
Balsam Fir (continued)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Barberry
Bentgrass (Astoria,
Highland) (seed
crop)
Bermudagrass
0.20 lb/5,000
sq.ft
(0.63% G)
Bishop Pine
2.00-2.60
(80% WP)
1.98-3.06
(90% WP)
Blue Spruce
$3503302
S3502402
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
N.F.
Dormant. Broadcast. Apply during the dormant
season, before weeds germinate. Apply when grass
is dry. Water thoroughly after application.
N.F.
Use limited to CA. Directed spray. Apply in at
least 25 gallons of water per acre in the fall or
spring, at least 1 year after transplanting. Do
not use on seedbeds or cutting beds. Do not apply
more than once per year.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
Issued: 9-11-79
1-080807-27
- 39 -
-------
/3426200
$3426202
S3532502
/3503400
$3503402
S3502402
/3448000
$3448002
S3502402
/3403700
$3403702
S3502402
/3527300
$3527302
S3532502
/3302300
Site, Dosage
and Formulation
(Ib a.i./A)
* Bottlebrush
Boxelder
Bush Honeysuckle
Caragana
Carob
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine for use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label «
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine for use and limitation information.
Centipedegrass (grown N.F.
for sod)
AZ state label
Registration Number 010163-06399
Issued: 9-11-79
1-080807-28
- 40 -
-------
$3302316
&080.0006
&090.0006
/3302400
$3302404
S2202804
/3504000
$3404002
S3514102
/ 3404500
$3404502
S3502402
/3504300
$3504302
S3501902
EPA Index to Pesticide Chemicals
SIMAZINE
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
Centipedegrass (grown for sod) (continued)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Chewing's Fescue
(seed crop)
Chinese Elm
Cotoneaster
Dogwood
Use limited to areas south of NC. Broadcast. Ap-
ply to old beds within 2 days after lifting of
sod. Apply to new beds on peat or muck soil, 3 to
4 days after sprigging or plugging. Apply 7 to 10
days after sprigging or plugging new beds on sandy
soil. Use the lower dosage on sandy soil and the
higher dosage on peat or muck soil. Apply in 20
to 40 gallons of water per acre. Repeat applica-
tion using one-half the initial dosage if regrowth
occurs. Do not apply within 30 days before cut-
ting or lifting.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Posteraer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
Issued: 9-11-79
1-080807-29
- 41 -
-------
73504400
$3504402
S3501902
Site, Dosage
and Formulation
(Ib a.i./A;
f Douglas-Fir
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
/3504500
$3504502
S3514102
/3505000
$3505002
&090.0006
Eastern Hemlock
&080.0006
/3405800
$3405802
S3514102
/3506100
$3506102
S3501902
Eucalyptus
1.98-3.06
(90% WP)
2.00-2.60
(80% WP)
Firethorn
Eraser Fir
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
Directed spray. Apply in a minimum of 25 gallons
of water per acre in the fall or spring, at least
1 year after transplanting. Do not use on seed-
beds or cutting beds. Do not apply more than
once per year.
Use limited to CA. Directed spray. Apply in a
minimum of 25 gallons of water per acre in the
fall or spring, at least 1 year after transplant-
ing. Do not use on seedbeds or cutting beds. Do
not apply more than once per year.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
AZ state label
0 Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
Issued: 9-11-79
1-080807-30
- 42 -
-------
/3506800
$3506802
S3502402
/3407000
$3407002
&090.0006
&080.0006
/3507000
$3507002
S3502402
/3430500
$3430502
S3514102
/3308400
$3308404
S2202804
Site, Dosage
and Formulation
(Ib a.i./A)
Hemlock
1.98-3.06
(90% WP)
2.00-2.60
(80% WP)
Honeylocust
Ilex convexa
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Directed spray. Apply in a minimum of 25 gallons
of water per acre in the fall or spring, at least
1 year after transplanting. Do not use on seed-
beds and cutting beds. Do not apply more than
once per year.
Use limited to WA. Directed spray. Apply in a
minimum of 25 gallons of water per acre in the
fall or spring, at least 1 year after transplant-
ing. Do not use on seedbeds and cutting beds. Do
not apply more than once per year.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
Illahee Fescue (seed N.F.
crop) Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
Issued: 9-11-79
1-080807-31
- 43 -
-------
/3408000
$3408002
S3514102
/3518700
$3518702
S3514102
/3507300
$3507302
S3501902
/3528200
$3528202
S3532502
/3507800
$3507802
S3505002
73519200
$3519202
S3514102
/3519600
$3519602
S3532502
Site, Dosage
and Formulation
(Ib a.i./AJ
* Japanese Holly
Japanese Maples
Juniper
Knobcone Pine
Lodgepole Pine
London Plane
Monterey Pine
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine for use and limitation information.
N.F.
Directed spray. Refer to Eucalyptus for use and
limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine for use and limitation information.
Issued: 9-11-79
1-080807-32
- 44 -
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
/3508600
Mugho Pine
$3508602
S3502402
/3509000
$3509002
S3501902
/3410200
$3410202
&045.0006
F
Norway Spruce
Oleander
3.15
(45% WP)
S3532502
/3304000
$3304004
S2202804
Orchardgrass (seed
crop)
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
Directed spray. Treat plants that have been
established for at least 1 year. Apply in the
spring or early summer before weeds mature.
Cut and remove tall weeds 2 weeks before applica-
tion. Apply in 100 gallons of water per acre.
Repeat if necessary.
Formulated with amitrole.
Use limited to CA. Directed spray. Refer to
Bishop Pine for additional use and limitation
information.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
Issued: 9-11-79
1-080807-33
- 45 -
-------
/3410300
$3410302
S3502402
/3301000
$3301002
&005.0010
F
/3509700
$3509702
&080.0006
&090.0006
/3311500
$3311504
S2202804
/3304300
$3304304
S2202804
Site. Dosage
and Formulation
(Ib a.i./A)
* Oregongrape
Ornamental Lawn
Borders
(5% Impr)
Palm
2.00
(80% WP)
1.98
(90% WP) •
Pennlawn Fescue
(seed crop)
Perennial Ryegrass
(seed crop)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Edging treatment. Cut vegetation and loosen soil
along area to be treated and fasten tape to the
area. Sprinkle the area intermittently to dis-
solve the tape. Do not use on steep slopes or
within the drip line of desirable shallow-rooted
plants.
Formulated with atrazine and related compounds.
N.F.
Use limited to CA. Directed spray. Apply in a
minimum of 25 gallons of water per acre in the
fall or spring, at least 1 year after transplant-
ing. Do not use on seedbeds and cutting beds.
Do not apply more than once per year.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
Issued: 9-11-79
1-080807-34
- 46 -
-------
/3411100
$3411102
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
Pieris
1.98-3.15
(90% WP)
&080.0006
2.00-3.20
(80% WP)
/3311400
$3311404
S2202804
/3510400
Rainier Fescue
(seed crop)
Redcedar
$3510402
S3502402
/3510500
Red Oak
$3510502
S3502402
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Directed spray. Apply in a minimum of 25 gallons
of water per acre in the fall or spring, at least
1 year after transplanting. Do not use on seed-
beds and cutting beds. Do not apply more than
once per year.
Use limited to WA. Directed spray. Apply in a
minimum of 25 gallons of water per acre in the
fall or spring, at least 1 year after transplant-
ing. Do not use on seedbeds and cutting beds.
Do not apply more than once per year.
N.F.
Do not graze treated areas for 30 days rollowing
application. Do not cut hay for 60 da/s following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orctiardgrass
(seed crop) for use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
Issued: 9-11-79
1-080807-35
- 47 -
-------
/3510600
$3510602
S3501902
/3510700
$3510702
S3501902
/3510900
$3510902
S3502402
/3511300
$3511302
S3501902
Site, Dosage
and Formulation
(Ib a.i./A)
* Red Pine
Red Spruce
Russian Olive
Scotch Pine
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
Issued: 9-11-79
1-080807-36
- 48 -
-------
/3511500
$3511502
S3502402
/3521100
$3521102
S3514102
/3305000
$3305016
S3302316
/3511900
$3511902
S3514102
/3305100
$3305104
S2202804
/3413700
$3413702
S3514102
/3522700
$3522702
S3514102
Site, Dosage
and Formulation
(Ib a.i./A)
* Siberian Elm
Silver Maple
St. Augustinegrass
(grown for sod)
Sycamore
Tall Fescue (seed
crop)
Viburnum
White Ash
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
Use limited to areas south of NC. Broadcast. Re-
fer to Centipedegrass (grown for sod) for use and
limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
Do not graze treated areas for 30 days following
application. Do not cut hay for 60 days following
application.
Use limited to the Pacific Northwest. Postemer-
gence. Refer to AGRICULTURAL CROPS, Orchardgrass
(seed crop) for use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
N.F.
Directed spray. Refer to American Beech for
use and limitation information.
Issued: 9-11-79
1-080807-37
- 49 -
-------
/3512500
$3512502
S3502402
/3522800
$3522802
S3505002
/3512600
$3512602
S3502402
/3512700
$3512702
S3501902
/3513000
$3513002
S3501902
Site. Dosage
and Formulation
(Ib a.i./A)
f. White Cedar
White Fir
White Pine
White Spruce
Yew
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
Directed Spray. Refer to Eucalyptus for use and
limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine for
use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to American Elm for use and limitation informa-
tion.
Issued: 9-11-79
1-080807-38
- 50 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
/3305600 * Zoysia Grass (grown N.F.
for sod)
$3305616
S3302316
AZ state label
Registration Number 010163-06399
Use limited to areas south of NC. Broadcast. Re-
fer to Centipedegrass (grown for sod) for use and
limitation information.
/6701300
RIGHTS-OF-WAY
Rights-of-Way
$6701302
&004.0004
19900300
19001500
&090.0006
&080.0006
&104.0014
10.00-40.00
(4% G)
4.77-39.66
(90% WP)
4.80-40.00
(80% WP)
(4 Ib/gal F1C)
N.F.
General Information: Rights-of-way include
roadways, highway medians, highways, railroads,
railyards, fire lanes, utilities, transformer
stations, pipelines, and around guard rails. Use
the higher dosages for perennial weed control,
for longer residual control, and in areas with
high rainfall or a long growing season.
AZ state labels
Registration Number 010163-06399
Registration Number 038059-09682
Formulated with sodium metaborate, sodium
chlorate, and prometone.
CA state labels
Registration Number 005481-03854
Formulated with atrazine and related compounds.
Registration Number 005481-03856
Registration Number 006973-04607
Broadcast. Apply before weed emergence or fol-
lowing weed removal. Apply the wettable powder
and flowable concentrate in a minimum of 1 gallon
of water per 0.8 pound active ingredient. If
weed growth has begun prior to application and
removal is not possible, tank mix with a contact
or translocated herbicide. Aerial applications
may be made where practical.
Issued: 9-11-79
1-080807-39
- 51 -
-------
&004.0004
&008.0004
&010.0004
&000.7505
Site, Dosage
and Formulation
(Ib a.i./A)
x Rights-of-Way (continued)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
8.00-34.85
(4% G)
10.45-20.00
(8% G)
15.00-22.50
(10% G)
1.63-6.53
(0.75% P/T)
Broadcast. Apply just before or after weed growth
begins.
Formulated with karbutilate; sodium metaborate
and sodium chlorate; or sodium metaborate, sodium
chlorate, and prometone.
COMMERCIAL AND INDUSTRIAL PREMISES
/6700000
$6700002
&004.0004
19900300
19001500
&090.0006
&080.0006
&104.0014
Noncrop Areas
10.00-40.00
(4% G)
4.77-39.66
(90% WP)
4.80-40.00
(80% WP)
(4 Ib/gal F1C)
N.F.
General Information:
k!oncrop areas include
industrial sites, storage areas, petroleum tank
farms, lumberyards, fencerows, airports, military
installations, transformer substations, and
around buildings, machinery and fuel tanks.
AZ state labels
Registration Number 010163-06399
Registration Number 038059-09682
Formulated with sodium metaborate, sodium
chlorate, and prometone.
CA state labels
Registration Number 005481-03854
Formulated with atrazine and related compounds.
Registration Number 005481-03858
Broadcast. Apply before weed emergence or fol-
lowing weed removal. Apply the wettable powder
and flowable concentrate in a minimum of 1 gallon
of water per 0.8 pound active ingredient. If
weed growth has begun prior to application and
removal is not possible, tank mix with a contact
or translocated herbicide. Aerial applications
may be made where practical.
Issued: 9-11-79
1-080807-40
- 52 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
, Nonerop Areas (continued)
&004.0004
.'*•
&008.0004
&010.0004
&000.7505
&045.0006
&100.8814
..- 8.00-34.85
I" (4% G)
'-"•' 10.45-20.00
(8% G)
15.00-22.50
(10% G)
- 1.63-6.53
(0.75% P/T)
9.00
(45% WP)
7.67-7.92
(0.88 Ib/gal F1C)
Broadcast. Apply just before or after weed growth
begins, usually in the spring or early summer.
Cut and remove tall weeds 2 weeks before applica-
tion. Apply the wettable powder in 100 gallons
of wafer per acre and the flowable concentrate in
a minimum of 50 gallons of water per acre.
Formulated with amitrole; karbutilate; sodium
metaborate and sodium chlorate; or sodium
metaborate, sodium chlorate, and prometone.
DOMESTIC DWELLINGS, MEDICAL FACILITIES AND SCHOOLS
/6700000
$6700002
&004.0004
19900300
19001500
&090.0006
&080.0006
&104.0014
Noncrop Areas
10.00-40.00
(4% G)
4.77-39.66
(90% WP)
4.80-40.00
(80% WP)
(4 Ib/gal F1C)
N.F.
General Information:
Noncrop areas include ceme-
teries, recreation areas, campsites, picnic areas,
tennis courts, ball diamonds, outdoor theaters,
paved areas, walkways, paths, patios, curbs,
driveways, parking areas, terraces, around build-
ings and fencprows. Use the higher dosages for
perennial weed control, for longer residual con-
trol, and in areas with high rainfall or a long
growing season.
CA state labels
Registration Number 006973-04607
Registration Number 011093-07123
Broadcast. Apply before weed emergence or fol-
lowing weed removal. Apply the wettable powder
and flowable concentrate in a minimum of 1 gallon
of water per 0.8 pound active ingredient. If
weed growth has begun prior to application and
removal is not possible, tank mix with a contact
or translocated herbicide. Aerial applications
may be made where practical.
Issued: 9-11-79
1-080807-41
- 53 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
Site, Dosage
and Formulation
(Ib a.i./A(lb a.i./A))
Tolerance, Use, Limitations
&004.0004'
&008.r»oo4
&000.7505
&045.0006
&100.8814
&000.7504
&001.0004
&001.0015
&203.0014
, Noncrop Areas (continued)
8.00-34.85
(4% G)
10.45-20.00
(8% G)
1.63-6.53
(0.75% P/T)
9.00
(45% WP)
7.67-7.92
(0.88 Ib/gal FIG)
0.50-2.00
Ib product/
100 sq.ft
(0.75% G)
2.00 Ib
product/100 sq.ft
(1% G)
2.00-3.00 Ib
product/100 sq.ft
(1% SC/S)
0.67 pt product/
100 sq.ft
(3% F1C)
Broadcast. Apply just before or after weed growth
begins, usually in the spring or early summer.
Cut and remove tall weeds 2 weeks before applica-
tion. Apply the wettable powder in 100 gallons of
water per acre, the 0.88 pound per gallon flowable
concentrate in a minimum of 50 gallons of water
per acre, the 3 percent flowable concentrate in
6.66 gallons of water per 1,000 square feet, and
the soluble concentrate in 40 gallons of water per
1,000 square feet.
Formulated with amitrole; sodium metaborate and
sodium chlorate; or sodium metaborate, sodium
chlorate, and prometone.
Issued: 9-11-79
1-080807-42
- 54 -
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and Formulation
(Ib a.i./A)
SIMAZINE
Tolerance, Use, Limitations
/3012600
$3012602
S3514102
/3012700
$3012702
S3514102
/3001900
$3001902
&004.0004
&080.0006
&090.0006
FOREST. CHAPARRAL, NONAGRICULTURAL AND WASTELANDS
General Warnings and Limitations: Do not use on seedbeds or cutting beds.
^n CA, OR and WA, do not apply to Christinas trees or shelterbelts within 1
year after transplanting. In other areas, do not apply to transplants
less than 3 years of age. Do not apply more than once a year, except as
directed for quackgrass control.
American Beech
(forest)
American Elm
(forest)
N.F.
Directed spray. Refer to ORNAMENTALS, American
Beech for use and limitation information.
N.F.
Directed spray. Refer to ORNAMENTALS, American
Beech for use and limitation information.
Arborvitae N.F.
(forestTshelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
2.00-4.00
(4% G)
(80% WP)
1.98-3.96
(90% WP)
Directed application. Broadcast or band. Remove
weed growth prior to application. Apply the wet-
table powder formulations in a minimum of 25 gal-
lons of water per acre. Use the same rate for
annual maintenance applications.
&004.0004
&080.0006
&090.0006
&045.0006
4.00
(4% G)
(80% WP)
3.96
(90% WP)
3.15
(45% WP)
Issued: 9-11-79
Directed application. Broadcast or band. Quack-
grass control. Apply once in the fall, or apply
as a split application, using one-half the dosage
in the fall and again in early spring after quack-
grass begins growth. Apply the wettable powder
formulations in a minimum of 25 gallons of water
per acre.
Directed spray. Treat plants that have been
established for at least 1 year. Apply in the
spring or early summer before weeds mature.
Cut and remove tall weeds 2 weeks before applica-
tion. Apply in 100 gallons of water per acre.
Repeat if necessary.
Formulated with araitrole.
1-080807-43
- 55 -
-------
/3008400
$3008402
&004.0004
&080.0006
&090.0006
&004.0004
&080.0006
&090.0006
/3012800
$3012802
S3001902
/3011100
$3011102
&080.0006
&090.0006
Site, Dosage
and Formulation
(Ib a.i./A)
Austrian Pine
(shelterbelt)
2.00-4.00
(4% G)
(80% WP)
1.98-3.96
(90% WP)
4.00
(4% G)
(80% WP)
3.96
(90% WP)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Broadcast or band. Remove
weed growth prior to application. Apply the wet-
table powder formulations in a minimum of 25 gal-
lons of water per acre. Use the same rate for
annual maintenance applications.
Directed application. Broadcast or band. Quack-
grass control. Apply once in the fall, or apply
as a split application, using one-half the dosage
in the fall and again in early spring after quack-
grass begins growth. Apply the wettable powder
formulations in a minimum of 25 gallons of water
per acre.
Balsam Fir (forest/ N.F.
shelterbelt)
Bishop Pine
(shelterbelt)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Arborvitae (forest/shelterbelt) for use and
limitation information.
N.F.
Use limited to CA. Directed spray. Broadcast or
band. Remove weed growth prior to application.
Apply in a minimum of 25 gallons of water per
acre. Use the same rate for annual maintenance
applications.
Issued: 9-11-79
1-080807-44
- 56 -
-------
&080.0006
&090.0006
/3002700
$3002702
&080.0006
&090.0006
/3014100
$3014102
S3008402
/3002900
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
* Bishop Pine (shelterbelt) (continued)
4.00
(80% WP)
3.96
(90% WP)
Black Walnut
(plantation)
2.00-4.00
(80% WP)
1.98-3.96
(90% WP)
Blue Spruce
(shelterbelt)
Boxelder
(shelterbelt)
Use limited to CA. Directed spray. Broadcast or
band. Quackgrass control. Apply once in the
fall, or apply as a split application, using
one-half the dosage in the fall and again in
early spring after quackgrass begins growth.
Apply in a minimum of 25 gallons of water per
acre.
N.F.
General Information;
series.
Do not use on seed nur-
$3002902
S3008402
Pretransplant or posttransplant. Broadcast or
band. Apply prior to weed emergence or following
removal of weed growth. If new growth is present,
apply as a directed spray, avoiding contact with
foliage. Apply in 20 to 100 gallons of water per
acre.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
Issued: 9-11-79
1-080807-45
- 57 -
-------
/3014000
$3014002
S3008402
/3000500
$3000502
S3008402
/3003900
$3003902
S3001902
/3012900
$3012902
S3001902
Site, Dosage
and Formulation
(Ib a.i./A)
- Caragana (shelter-
belt)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Christmas Tree
Plantation
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
Douglas-Fir (forest/ N.F.
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Arborvitae (forest/shelterbelt) for use and
limitation information.
Fraser Fir (forest/ N.F.
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Arborvitae (forest/shelterbelt) for use and
limitation information.
Issued: 9-11-79
1-080807-46
- 58 -
-------
EPA Index to Pesticide Chemicals
/3004600
$3004602
S3008402
/3011500
$3011502
&090.0006
&080.0006
&090.0006
&080.0006
/3004800
Site, Dosage
and Formulation
(Ib a.i./A)
1 Hemlock (shelterbelt) N.F.
SIMAZINE
Tolerance, Use, Limitations
1.98-3.15
(90% WP)
2.00-3.00
(80% WP)
3.15
(90% WP)
3.20
(80% WP)
Honeylocust
(shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
Holly (shelterbelt) N.F.
Directed spray. Broadcast or band. Remove weed
growth prior to application. Apply in a minimum
of 25 gallons of water per acre. Use the same
rate for annual maintenance applications.
Directed spray. Broadcast or band. Quackgrass
control. Apply once in the fall, or apply as a
split application, using one-half the dosage in
the fall and again in early spring after quack-
grass begins growth. Apply in a minimum of 25
gallons of water per acre.
N.F.
$3004802
S3008402
/3005000
Juniper (forest/
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
$3005002
S3001902
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer to
Arborvitae (forest/shelterbelt) for use and
limitation information.
Issued: 9-11-79
1-080807-47
- 59 -
-------
/3008300
$3008302
S3011102
/3009700
$3009702
&080.0006
&090.0006
19900300
&080.0006
&090.0006
/3009800
$3009802
S3008402
/3011200
$3011202
S3011102
Site, Dosage
and Formulation
(Ib a.i./AJ
f Knobcone Pine
(shelter-belt)
Loblolly Pine
(plantation)
4.00-6.00
(80% WP)
3.96-5.94
(90% WP)
3.20-4.80
(80% WP)
3.15-4.77
(90% WP)
Lodgepole Pine
(shelterbelt)
Monterey Pine
(shelterbelt)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine (shelterbelt) for use and limitation
information.
N.F.
General Information;
series.
Do not use on seed nur-
Use limited to the South; for establishment only.
Pretransplant or posttransplant. Broadcast or
band. Apply prior to weed emergence or following
removal of weed growth. If new growth is present,
apply as a directed spray, avoiding contact with
foliage. Apply in 20 to 100 gallons of water per
acre.
Use limited to the South; for establishment only.
Pretransplant or posttransplant. Broadcast or
band. Apply prior to weed emergence or following
removal of weed growth. If new growth is present,
apply as a directed spray avoiding contact with
foliage. Apply in 20 to 100 gallons of water per
acre. May be tank mixed with atrazine and related
compounds.
N.F.
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
Use limited to CA. Directed spray. Refer to
Bishop Pine (shelterbelt) for use and limitation
information.
Issued: 9-11-79
1-080807-48
- 60 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
/3013000
$3013002
S3001902
Norway Spruce
(forest/shelterbelt)
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation information.
/3006100
Redcedar
Uhelterbelt)
N.F.
$3006102
S3008402
/3010300
Red Pine (forest/
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
$3010302
S3001902
/3012500
Red Spruce (forest/
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation information.
N.F.
$3012502
S3001902
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation informations
Issued: 9-11-79
1-080807-49
- 61 -
-------
/3012100
$3012102
S3008402
/3011300
$3011302
S3001902
/3013100
$3013102
S3514102
/3010400
$3010402
&080.0006
&090.0006
/3006600
$3006602
S3514102
/3013200
$3013202
S3514102
Site, Dosage
and Formulation
(Ib a.i./A)
* Russian Olive
(shelterbelt)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
Scotch Pine (forest/ N.F.
shelterbelt)
AZ state label
Registration Number 010163-06399
CA state label
Registration Number 005481-03858
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation information.
Silver Maple (forest) N.F.
Slash Pine
(plantation)
4.00-6.00
(80% WP)
3.96-5.94
(90% WP)
Sycamore (forest)
White Ash (forest)
Issued: 9-11-79
Directed spray. Refer to ORNAMENTALS, American
Beech for use and limitation information.
N.F.
General Information; Do not use on seed nur-
series.
Use limited to the South; for establishment only.
Pretransplant or posttransplant. Broadcast or
band. Apply prior to weed emergence or following
removal of weed growth. If new growth is present,
apply as a directed spray, avoiding contact with
foliage. Apply in 20 to 100 gallons of water per
acre.
N.F.
Directed spray. Refer to ORNAMENTALS, American
Beech for use and limitation information.
N.F.
Directed spray. Refer to ORNAMENTALS, American
Beech for use and limitation information.
1-080807-50
- 62 -
-------
/3009200
$3009202
S3008402
/3013500
$3013502
S3010402
/3010800
$3010802
S3001902
/3007300
$3007302
S3001902
Site, Dosage
and Formulation
(Ib a.i./A)
, White Fir
" (shelterbelt)
White Pine
(plantation)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
N.F.
Directed application. Refer to Austrian Pine
(shelterbelt) for use and limitation information.
N.F.
General Information: Do not use on seed nur-
series.
Use limited to the South; for establishment only.
Pretransplant or posttransplant. Refer to Slash
Pine (plantation) for use and limitation informa-
tion.
White Spruce (forest/ N.F.
shelterbelt)
Yew (forest/shelter-
belt)
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation information.
N.F.
Directed spray and directed application. Refer
to Arborvitae (forest/shelterbelt) for use and
limitation information.
Issued: 9-11-79
1-080807-51
- 63 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
AQUATIC AREAS
General Warnings and Limitations; Water temperature of 80 F (26.7 C) or
greater results in faster algae control.
(Industrial)
/6501900
$6501961
&201.0016
&201.0016
/6501300
$6501362
&004.0004
19900300
&090.0006
&080.0006
&104.0014
Commercial and
Industrial Water
Cooling Tower
Systems
96.00-134.00
fl.oz product/
1,000 gal
(1% RTU)
2.00-58.00
fl.oz product/
1,000 gal
(1% RTU)
(Adjacent to Water)
Drainage Ditch Banks
N.F.
General Information:
Use only in industrial re-
10.00-40.00
(4% G)
4.77-39.66
(90% WP)
4.80-40.00
(80% WP)
(4 Ib/gal F1C)
circulating water cooling towers under 25,000
tons (250,000 gallons capacity). Apply one-half
of the dosage when one-half of the water in the
system has been lost by blow-down.
Water treatment. Shock treatment. Clean badly
fouled systems before treatment. Apply at a point
in the system where the product will be uniformly
mixed.
Water treatment. Maintenance application. Apply
when control is evident.
N.F. '
General Information:
Use the higher dosage for
prennial weed control, for longer residual con-
trol, and in areas with high rainfall or a long
growing period.
CA state label
Registration Number 011093-07123
Broadcast. Apply before weed emergence or follow-
ing weed removal. Apply the wettable powder and
flowable concentrate in a minimum of 1 gallon of
water per 0.8 pound active ingredient. If weed
growth has begun prior to application and removal
is not possible, tank mix with a contact or trans-
located herbicide.
Issued: 9-11-79
1-080807-52
- 64 -
-------
&004.0004
&000.7505
/6502300
$6502361
&080.0006
&200.1016
&200.6016
F
&000.5506
&001.1006
Site, Dosage
and Formulation
(Ib a.i./A)
, Drainage Ditch Banks (continued)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
&000.5505
&000.6005
8.00-34.85
(4% G)
1.63-6.53
(0.75% P/T)
Broadcast. Apply just before or after weed growth
begins.
Formulated with sodium metaborate and sodium
chlorate; or sodium metaborate, sodium chlorate,
and prometone.
(Ornamental and Recreational)
Aquaria, Ornamental
Fish Ponds and
Fountains
1.33 oz product/
10,000 gal
(80% WP)
N.F.
General Information; Treatment is normally effec-
tive for several weeks. Repeat treatment when
algae reappear. For heavy algal growth repeat in
6 or 7 days. Decayed algae should be removed
prior to second application.
Water treatment. Mix the product in water and
distribute evenly over the surface to be treated.
1.00 tbls product/ Water treatment.
5 gal
(0.1% RTU)
1.00 tsp product/
10 gal
(0.6% RTU)
0.41 oz product/
100 gal
(0.55% WP)
0.32 oz product/
100 gal
(1.1% WP)
2 tablets/10 gal
(0.55% P/T)
(0.6% P/T)
Water treatment. Apply when the pond is clean or
when algae become visible. Mix the dosage in a
pail of water. Do not mix more than 4 ounces of
product at a time. Slowly pour the mixture into
the water around the edge of the pond. Do not
pour the concentrated mixture directly onto
desirable aquatic plants.
Formulated with monuron and atrazine and related
compounds; or chlorine, monuron, and atrazine and
related compounds.
Water treatment. Initial application. Apply to
a clean aquarium.
Formulated with dichlone, monuron, and atrazine
and related compounds.
Issued: 9-11-79
1-080807-53
- 65 -
-------
&000.5505
&000.6005
/6501100
$6501161
&011.0004
&080.0006
&201.0016
&207.5014
EPA Index to Pesticide Chemicals
SIMAZINE
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
, Aquaria, Ornamental Fish Ponds and Fountains (continued)
' s
1 tablet/10 gal Water treatment. Maintenance application. Apply
(0.55% P/T) every 2 weeks. For aquaria smaller than 5 gal-
' (0.6% P/T) Ions, apply 1 tablet every month.
Formulated with dichlone, monuron, and atrazine
and related compounds.
&012.0004 '
&012.0005 /
Swimming Pools
1.60 Ib product/
10,000 gal
(11% G)
2.67 oz product/
10,000 gal
(80% WP)
N.F.
CA state labels
Registration Number 000266-06907
Registration Number 009610-10190
Registration Number 011005-06908
Water treatment. Black algae control. Initial
application. Apply when algae are first visible.
Mix the dosage in water and pour into skimmer or
distribute evenly around edges of pool. To
accelerate results, remove top of algal growth
with wire brush daily and vacuum out settled
algae. After 1 week initiate maintenance appli-
cation.
205.00 fl.oz Water treatment. Black algae control. Initial
product/10,000 gal application. Apply when algae are first visible.
(1% RTU) Pour into skimmer or distribute evenly around
edges of pool. To accelerate results, remove top
of algal growth with wire brush daily and vacuum
out settled algae. After 1 week initiate main-
tenance application.
12.00 fl.oz Water treatment. Black algae control. Initial
product/10,000 gal application. Apply to a pool with established
(7.5% FIC) black algae. Mix the dosage in water and
distribute evenly throughout the pool.
Formulated with sodium dimethyldithiocarbamate.
8.00 oz product/
10,000 gal
(12% G)
(12% P/T)
Issued: 9-11-79
Water treatment. Black algae control. Initial
application. Apply to a pool with established
black algae. Apply the product in the areas
where the algae are growing. If severe infesta-
tions are present, the filters should be turned
off for 4 to 6 hours during the treatment.
Repeat the treatment twice a week until control
is established.
Formulated with sodium dichloro-s-triazinetrione;
or sodium dichloro-s-triazinetrione and tri-
chloro-s-triazinetrione.
1-080807-54
- 66 -
-------
&012.0004
&207.5014
&080.0006
&011.0004
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
f Swimming Pools (continued)
4.00 oz product/
10,000 gal
(12% G)
(7.5% F1C)
2.00 oz product/
10,000 gal
(80% WP)
1.20 Ib product/
10,000 gal
(11% G)
Water treatment. Black algae control. Mainten-
ance application. Mix the dosage in water or
apply directly to the pool. Distribute evenly
throughout the pool. Repeat treatment 1 or 2
times weekly.
Formulated with sodium dimethyldithiocarbamate;
sodium dichloro-s-triazinetrione; or sodium
dichloro-s-triazinetrione and trichloro-s-
triazinetrione.
Water treatment. Initial application. Apply
when algae are first visible. Mix the dosage in
water and pour into skimmer or distribute evenly
around edges of pool. One week after treatment,
brush algae from walls. Vacuum out settled algae
and initiate maintenance application.
&201.0016
&012.0004
&012.0004
&012.0005
&207.5014
&203.5014
136.00 fl.oz Water treatment. Initial application. Apply
product/10,000 gal when algae are first visible. Pour into skimmer
(1% RTU) or distribute evenly around edges of pool. One
week after treatment, brush algae from walls.
Vacuum out settled algae and initiate maintenance
application.
4.00 oz product/
10,000 gal
(12% G)
8.00 oz product/
10,000 gal
(12% G)
(12% P/T)
12.00 fl.oz
product/10,000 gal
(7.5% F1C)
12-18 ppm product
(3.5% F1C)
Water treatment. Initial application. Apply to
a pool with visible algae. Mix the dosage in
water or apply directly to the pool. Distribute
evenly throughout the pool. Repeat treatment 1
or 2 times a week until control is established.
Formulated with sodium dimethyldithiocarbamate;
poly(oxyethylene(dimethylimino)ethylene-
(dimethylimino)ethylene dichloride); sodium
dichloro-s-triazinetrione; or sodium dichloro-s-
triazinetrione and trichloro-s-triazinetrione.
Issued: 9-11-79
1-080807-55
- 67 -
-------
&207.5014
&011.0004
&080.0006
&201.0016
&207.5014
&203.5014
&203.0014
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
f Swimming Pools (continued)
8.00 fl.oz Water treatment. Initial application. Apply to
, product/10,000 gal a pool with no visible algae. Mix the dosage in
(7.5% F1C) water and distribute evenly throughout the pool.
Formulated with sodium dimethyldithiocarbamate.
0.80 Ib product/
10,000 gal
(11% G)
1.33 oz product/
10,000 gal
(80% WP)
Water treatment. Maintenance application. Apply
to a clean pool. Mix the dosage in water and pour
into the skimmer or distribute evenly around edges
of pool. Repeat treatment every 8 to 10 weeks or
when algae reappear.
103.00 fl.oz Water treatment. Maintenance application. Apply
product/10,000 gal to a clean pool. Pour into the skimmer or distri-
(1% RTU) bute evenly around edges of pool. Repeat treat-
ment every 8 to 10 weeks or when algae reappear.
4.00 fl.oz product/ Water treatment. Maintenance application. Mix
10,000 gal
(7.5% F1C)
3-6 ppm product
(3.5% F1C)
the dosage in water or apply directly to the pool.
Distribute evenly throughout the pool. Repeat
treatment weekly or when algae reappear.
Formulated with sodium dimethyldithiocarbamate;
or poly(oxyethylene(dimethylimino)ethylene-
(dimethylimino)ethylene dichloride).
42.50 fl.oz Water treatment. Winterizing application. Apply
product/10,000 gal when the swimming season has ended and after the
(3% F1C) pool has been cleaned and shut off. If algae
reappear, repeat the treatment.
Formulated with poly(oxyethylene(dimethylimino)
ethylene(dimethylimino)ethylene dichloride).
Issued: 9-11-79
1-080807-56
- 68 -
-------
Site, Dosage
and Formulation
(Ib a.i./A)
AND TANK MIX APPLICATIONS
EPA Index Co Pesticide Chemicals
SIMAZINE
Tolerance, Use, Limitations
Aerial Application
Tank Mix
Refer to
AGRICULTURAL CROPS
Alfalfa, Alfalfa-Orchardgrass Mixture,
Bermudagrass, Corn
AGRICULTURAL PREMISES
All sites
RIGHTS-OF-WAY
All sites
COMMERCIAL AND INDUSTRIAL PREMISES
All sites
Refer to
AGRICULTURAL CROPS
Alfalfa, Almond, Apple, Cherry, Corn, Filbert,
Grapefruit, Grapes, Lemon, Orange, Peach, Pear,
Pecan, Plum, Walnut
AGRICULTURAL PREMISES
All sites
RIGHTS-OF-WAY
All sites
COMMERCIAL AND INDUSTRIAL PREMISES
All sites
DOMESTIC DWELLINGS, MEDICAL FACILITIES AND SCHOOLS
All sites
FOREST. CHAPARRAL, NONAGRICULTURAL AND WASTELANDS
Loblolly Pine (plantation)
Issued: 9-11-79
1-080807-57
- 69 -
-------
&095.0001
&098.0001
EPA Index to Pesticide Chemicals
SIMAZINE
Listing of Registered Pesticide Products by Formulation
95% technical chemical
simazine (080807)
t. 002749-00292 013801-00006
&097.0001 97% technical chemical
# / simazine (080807)
000100-00541
98% technical chemical
simazine (080807)
039511-00005
&080.0002 80% formulation intermediate
# simazine (080807)
011603-00011
&000.1704 0.167% granular
# simazine (080807)
000100-00500 002342-00749
&000.2504 0.25% granular
# simazine (080807)
000072-00564 000100-00499 000477-00286 002342-00748
008590-00442
&000.6304 0.63% granular
# simazine (080807)
007401-00192
&000.7504 0.75% granular
simazine (080807), sodium metaborate (011104), sodium chlorate (073301)
# plus prometone (080804)
000100-00574 038059-09682
&001.0004 1% granular
simazine (080807), sodium metaborate (011104) plus sodium chlorate
# (073301)
000239-02232
&001.5004 1.5% granular
* simazine (080807)
006973-04607 011093-07123
&002.0004 2% granular
# simazine (080807)
011656-00047 011656-05903
# simazine (080807) plus atrazine and related compounds (080803)
005481-03854
Issued: 9-11-79
1-080807-58
- 70 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
Listing of Registered Pesticide Products by Formulation (continued)
&004.0004 4% granular
# simazine (080807)
, 000072-00289 000100-00435 000912-00075 001022-00431
003743-00264 005481-03856
simazine (080807), sodium metaborate (011104) plus sodium chlorate
# ' (073301)
000100-00476 001022-00433
&008.0004 8% granular
# simazine (080807)
001022-00418
simazine (080807), sodium metaborate (011104) plus sodium chlorate
# (073301)
001022-00422
010.0004 10% granular
# simazine (080807) plus karbutilate (097401)
000100-00595
*
&011.0004 11% granular
# simazine (080807)
007124-00032
&012.0004 12% granular
# simazine (080807) plus sodium dichloro-s-triazinetrione (081404)
007364-00027
simazine (080807), sodium dichloro-s-triazinetrione (081404) plus
# trichloro-s-triazinetrione (081405)
007364-00014
&000.5505 0.55% pelleted/tableted
simazine (080807), dichlone (029601), monuron (035501) plus atrazine
# and related compounds (080803)
007364-00003 007364-00008
&000.6005 0.6% pelleted/tableted
simazine (080807), dichlone (029601), monuron (035501) plus atrazine
# and related compounds (080803)
008709-00001
&000.7505 0.75% pelleted/tableted
simazine (080807), sodium metaborate (011104), sodium chlorate (073301)
# plus prometone (080804)
000100-00479
Issued: 9-11-79
1-080807-59
- 71 -
-------
&012.0005
#
&000.5506
#
&001.1006
&045.0006
#
&080.0006
EPA Index to Pesticide Chemicals
SIMAZINE
Listing of Registered Pesticide Products by Formulation (continued)
12% pelleted/tableted
simazine (080807), sodium dichloro-s-triazinetrione (081404) plus
f trichloro-s-triazinetrione (081405)
007364-00015
Q.55% wettable powder
simazine (080807), dichlone (029601), monuron (035501) plus atrazine
and related compounds (080803)
007476-00001
1.1% wettable powder
simazine (080807), monuron (035501) plus atrazine and related
compounds (080803)
007364-00004
45% wettable powder
simazine (080807) plus amitrole (004401)
000264-00124
000100-04283
007001-00185
013765-00002
000100-04296
008791-00014
013765-00003
&090.0006
&0005.0010
&100.8814
#
&104.0014
80% wettable powder
simazine (080807)
000100-00437 000100-00570
000464-00483 002749-00163
009610-10190 010163-06399
039511-00012
90% wettable powder
simazine (080807)
000100-00603
5% impregnated materials
simazine (080807) plus atrazine and related compounds (080803)
010780-00001
0.88 Ib/gal flowable concentrate
simazine (080807) plus amitrole (004401)
000264-00196
4 Ib/gal flowable concentrate
simazine (080807)
000100-00526
&203.0014 3% flowable concentrate
simazine (080807) plus amitrole (004401)
000264-00156
simazine (080807) plus poly(oxyethylene(dimethylimino)ethy lene-
(dimethylimino)ethylene dichloride) (069183)
003432-00033
Issued: 9-11-79
1-080807-60
- 72 -
-------
EPA Index to Pesticide Chemicals
SIMAZINE
Listing of Registered Pesticide Products by Formulation (continued)
&203.5014 3.5% flovable concentrate
simazine (080807) plus poly(oxyethylene(dimethylimino)ethylene-
# * (dimethylimino)ethylene dichloride) (069183)
007364-00023
&207.5014 7.5% flovable concentrate
# simazine (080807) plus sodium dimethyldithiocarbamate (034804)
007364-00011
&001.0015 1% soluble concentrate/solid
simazine (080807), sodium metaborate (011104) plus sodium chlorate
# (073301)
000239-02232
&020.0015 20% soluble concentrate/solid
# simazine (080807)
000266-06907 011005-06908
&200.6015 0.6% soluble concentrate/liquid
# simazine (080807)
007689-00014
&200.1016 0.1% liquid-ready to use
# simazine (080807)
013765-00001
&201.0016 1% liquid-ready to use
# simazine (080807)
001769-00234 001769-00245
Issued: 9-11-79
1-080807-61
- 73 -
-------
II. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
A. This portion of the guidance document is a Notice
issued under the authority of FIFRA Section 3(c)(2)(B)
and describes, in table format/ the data required
for maintaining the registrability of each product.
Additionally, a bibliography (Appendix II-l) is
included that identifies that data considered as
part of the data base supporting this standard. EPA
has determined that additional generic data described
in this Notice must be submitted to EPA for evaluation
in order to maintain in effect the registration(s)
of your product(s) identified as an attachment to
the cover letter accompanying this guidance document.
As required by FIFRA Section 3(c)(2)(B),.you are
required to take appropriate steps to comply with
this Notice.
EPA may suspend the registration of each of those products
unless, within the specified time, you have informed EPA
how you will satisfy the requirements of this Notice.
Any such suspension will remain in effect until you have
complied with the terms of this Notice.
B. What Generic Data I/ Must Be Submitted. You may ascertain
which generic data you must submit by consulting Table A
at the end of this chapter. That table shows all the
generic data needed to evaluate the continued registrability
of all products, and the dates by which the data must be
submitted. The required data must be submitted and any
necessary studies must be conducted in accordance with
EPA-approved protocols, the Pesticide Registration
Guidelines 2/, or data collected under the approved
protocols of the Organization for Economic Cooperation
and Development (OECD). If you wish not to develop data
which are necessary to support the registration or
reregistration of certain uses appearing in your labeling,
you may delete those uses at the time you submit your
revised labeling.
Also for certain kinds of testing (generally ecological
effects), EPA requires the test substance to be a "typical
formulation," and in those cases EPA needs data of that
I/ Generic data pertain to the properties or effects of a
particular ingredient, and thus are relevant to an evaluation of
the risks of all products containing that ingredient (or all such
products having a certain use pattern), regardless of any such
product's unique composition or use. Product-specific data relate
only to the properties or effects of a product with a particular
composition (or a group of products with closely similar composition)
2/ The Pesticide Registration Guidelines were reproposed on
November 24, 1982 in 47 Federal Register 53192.
- 74 -
-------
type for each major formulation category (e.g., emulsifiable
concentrates, wettable powders, granulars, etc.) These
are classified as generic data and when needed are
specified in Table A. EPA may possess data on certain
"typical formulations" but not others. Note; The "typical
formulation" data should not be confused with product-
specific data (Table B) which are required on each
formulation. Product-specific data are further explained
in Chapter IV of this document.
/
C. Options Available for Complying With Requirements
to Submit Data
Within 90 days of your receipt of this Notice you must
submit to EPA a completed copy of the form entitled "FIFRA
Section 3(c)(2)(B) Summary Sheet" [EPA Form 8580-1, Appendix
II-2] for each of your products. On that form you must
state which of the following methods you will use to comply
with the requirements of this Notice:
1. (a) Notify EPA that you will submit the data, and
(b) either submit the existing data you believe
will satisfy the requirement, or state that
you will generate the data by conducting
testing. If the test procedures you will
use deviate from (or are not specified in)
the Registration Guidelines or protocols
contained in the Reports of Expert Groups
to the Chemicals Group, Organization for
Economic Cooperation and Development (OECD)
Chemicals Testing Programme, you must enclose
the protocols you will use.
2. Notify EPA that you have entered into an agreement
with one or more other registrants to jointly
develop (or share in the cost of developing) the
data. If you elect this option, you must notify EPA
which registrant(s) are parties to the agreement.
3. File with EPA a completed "Certification of Attempt to
Enter Into an Agreement With Other Registrants for
Development of Data" (EPA Form 8580-6, Appendix II-3)V
4. Request that EPA amend your registration by deleting the
uses for which the data are needed. (This option is not
available to applicants for new products.)
V FIFRA Section 3(c)(2)(B) authorizes joint development of
data by two or more registrants, and provides a mechanism by
which parties can obtain an arbitrator's decision if they agree
to jointly develop data but fail to agree on all the terms of
the agreement. The statute does not compel any registrant to
agree to develop data jointly.
(Footnote continued at bottom of next page)
- 75 -
-------
5. Request voluntary cancellation of the registration(s).
of your products for which the data are needed. (This
option is not available to applicants for new products.)
D. Procedures for Requesting Changes in Testing Methodology
and Extensions of Time
EPA recognizes that you may disagree with our conclusions
regarding the appropriate ways to develop the required
data or how quickly the data must be submitted. If the
test procedures you plan to use deviate from (or are not
specified in) the registration guidelines or protocols
contained in the reports of the Expert Groups to the
Chemical Groups, Organization for Economic Cooperation
and Development (OECO) Chemicals Testing Programme, you
must submit the protocol for Agency review prior to the
initiation of the test.
If you think that you will need more time to generate the
required data than is allowed by EPA's schedule, you may
submit a request for an extension of time. The extension
request must be submitted in writing to the Product
Manager. The extension request should state the reasons
why you conclude that an extension is appropriate. While
EPA considers your request, you must strive to meet the
deadline for submitting the required data.
(Footnote continued from previous page)
In EPA's opinion, joint data development by all registrants
who are subject to the requirements to submit a pertinent item
of data or a cost-sharing.agreement among all such registrants
is clearly in the public interest. Duplication of testing could
increase costs, tie up testing facilities, and subject an unneces-
sarily large number of animals to testing.
As noted earlier, EPA has discretion not to suspend the
registration of a product when a registrant fails to submit data
required under FIFRA Section 3(c)(2)(B). EPA has concluded that
it is appropriate to exercise its discretion not to suspend in
ways which will discourage duplicative testing. Accordingly, if
(1) a registrant has informed us of his intent to develop and
submit data required by this Notice; and (2) a second regis-
trant informs EPA that it has made a bona fide offer to the
first registrant to share in the expenses of the testing [on
terms to be agreed upon or determined by arbitration under FIFRA
Section 3(c)(2)(B)(iii)]; and (3) the first registrant has declined
to agree to enter into a cost-sharing agreement, EPA will not
suspend the second firm's registration. While the first firm is
not required to agree to jointly develop data, EPA is not required
to force the second firm to engage in economically inefficient
duplicative testing in order to maintain its registration.
- 76 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NO. 100-541 (97% T)i/
Data Requirement
Does EPA Have Data
to Satisfy This
Composition?/ Requirement? (yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Mate-
rials and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples
62-2 - Certification of Ingredient
Limits
62-3 - Analytical Methods to Verify
Certified Limits
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
Yes
Partially
No
No
No
No
00023955
GS-650070-1
GS-650070-2
GS-650070-5
GS-650070-6
00023955
GS-650070-1
GS-650070-2
GS-650070-5
No
Yes
Yes
Yes
Yes
Yes
- 77 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NO. 100-541 (97% T)l/
Data Requirement
Compos it ion2/
Must Additional
Does EPA Have Data Data Be Submitted
to Satisfy This Bibliographic Under FIFRA Section
Requirement? (Yes, Citation 3(c) (2) (B)?3/
No or Partially)
158.120 Product Chemistry (continued)
Physical and Chemical Characteristics
63- 2
63- 3
63- 4
63- 5
63- 6
63- 7
63- 8
63- 9
63-10
63-11
63-12
63-13
- Color
- Physical State
- Odor
- Melting Point
- Boiling Point
- Density, Bulk Density, or
Specific Gravity
- Solubility
- Vapor Pressure
- Dissociation Constant
- Octanol/Water Partition
Coefficient
- PH
- Stability
TGAI
TGAI
TGAI
TGAI
N/A
TGAI
TGAI OR PAI
• PAI
PAI
PAI
TGAI
TGAI
Yes
Yes
Yes
Yes
N/A
Yes
Yes
Yes
No
No
N/A
Yes
00023955 No
00023955 No
00023955 No
00023955 No
Nojy
00023955 No
00023955 No
00023955 No
Yes
Yes
No!/
00023955 No
- 78 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NO. 100-541 (97% T)i/
Data Requirement
Compos i t ionE/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
Other Requirements;
64- 1 - Submittal of samples
N/A
N/A
No
I/ The 97% technical (T) also serves as a manufacturing-use product.
2/ Composition: TGAI = technical grade of the active ingredient; PAI = pure active ingredient.
3/ Data must be submitted no later than six months after receipt of this guidance package.
4/ Since Simazine is practically insoluble in water no pH is required.
.§/ Not required if formulation is a solid at room temperature.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 79 -
-------
TABLE B
GENERIC DATA REQUIREMENTS FDR SIMAZINE, EPA REG. NO. 19713-59 (98% T)l/
Data Requirement
Composition2/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
15R.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Mate-
rials and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples
62-2 - Certification of Ingredient
Limits
62-3 - Analytical Methods to Verify
Limits
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
Yes
Partially
No
No
No
No
00023955
GS-650070-1
GS-650070-2
GS-650070-3
GS-650070-10
00023955
GS-650070-1
GS-650070-2
GS-650070-3
No
Yes
Yes
Yes
Yes
Yes
- 80 -
-------
TABLE B
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NO. 19713-59 (98% T)!/
Data Requirement
158.120 Product Chemistry (continued)
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
63- 5 - Melting Point
63- 6 - Boiling Point
63- 7 - Density, Bulk Density, or
Specific Gravity
63- 8 - Solubility
63- 9 - Vapor Pressure
63-10 - Dissociation Constant
Composition?/
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI OR PAI
PAI
PAI
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
No
No
No
No
No
No
No
No
No
Must Additional
Data Be Submitted
Bibliographic Under FIFRA Section
Citation 3(c)(2)(B)?3/
Yes
Yes
Yes
Yes
Yesi/
Yes
Yes
Yes
Yes
63-11 - Octanol/Water Partition
Coefficient
63-12 - pH
63-13 - Stability
PAI
TGAI
TGAI
No
No
NO
Yes
Yes
- 81 _
-------
TABLE B
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NO. 19713-59 (98% T)l/
Data Requirement
Compos i t i
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.120 Product Chemistry (Continued)
Other Requirements;
64- 1 - Submittal of samples
N/A
N/A
No
I/ The 98% technical (T) also serves as a manufacturing-use product.
2/ Composition: TGAI = technical grade of the active ingredient; PAI = pure active ingredient.
3y Data must be submitted no later than six months after receipt of this guidance package.
i/ Not required if the 98% technical is a solid at room temperature.
jj/ Since Simazine is practically insoluable in water no pH is required.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 82 -
-------
TABLE C
GENERIC DATA REQUIREMENTS FDR SIMAZINE, EPA REG. NOS. 2749-292 (95% T), 1812-262 (95% T), AND 39511-5 (98%
Data Requirement
Composition?/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Mate-
rials and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples
Physical and Chemical Charcteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
63-5 - Melting Point
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
Yes
No
No
No
NO
No
No
No
00023955
GS-650070-1
GS-650070-2
GS-650070-7
GS-650070-8
GS-650070-11
No
Yes
Yes
Yes
Yes
Yes
Yes
Yes
- 83 -
-------
TABLE C
GENERIC DATA REQUIREMENTS FOR SIMAZINE, EPA REG. NOS. 2749-292 (95% T), 1812-262 (95% T), AND 39511-5 (98% T)l/
Data Requirement
Conpos i t ion?/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.120 Product Chemistry (continued)
63- 6
63- 7
63- 8
63- 9
63-10
63-11
63-12
63-13
Other
64- 1
- Boiling Point
- Density, Bulk Density, or
Specific Gravity
- Solubility
- Vapor Pressure
- Dissociation Constant
- Octanol/Water Partition
Coefficient
- pH
- Stability
Requirements:
- Submittal of samples
TGAI
TGAI
TGAI OR PAI
PAI
PAI
PAI
TGAI
TGAI
N/A
No
No
No
No
No
No
No
No
N/A
Yesi/
Yes
Yes
Yes
Yes
Yes
Nol/
Yes
No
I/ The technicals (T) also serve as manufacturing-use products.
2/ Composition: TGAI = technical grade of the active ingredient; PAI = pure active ingredient.
3/ Data must be submitted no later than six months after receipt of this guidance package.
4/ Not required if the technical products are solids at room temperature.
Jt/ Since Simazine is practically insoluable in water no pH is required.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 84 -
-------
TABLF D
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NOS.
2749-292 (95% T), 1812-262 (95% T), 39511-5 (98% T) AND 11603-11 (80% FI).
Data Requirement
Camposition!/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Mate-
; rials and Manufacturing Process
, i
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples
62-2 - Certification of Ingredient Limits
62-3 - Analytical Methods to
Verify Certified Limits
MP
MP
MP
MP
MP
MP
Yes
No
No
No
Partially!/
Partially
GS-650070-4
GS-650070-7
GS-650070-8
GS-650070-9
GS-650070-11
- 85 -
GS-650070-4
GS-650070-7
GS-650070-8
GS-650070-9
GS-650070-11
GS-650070-4
GS-650070-7
GS-650070-8
GS-650070-9
GS-650070-11
No
Yes
Yes
Yes
Yes
Yes
-------
TABLE D
PRODUCT SPECIFIC DATA REQUIREMENTS FDR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NOS.
2749-292 (95% T), 1812-262 (95% T), 39511-5 (98% T) AND 11603-11 (80% FI).
Data Requirement
158.120 Product Chemistry (continued)
Physical and Chemical Characteristics
63- 2 - Color
63- 3 - Physical State
63- 4 - Odor
63- 7 - Density, Bulk Density, or
Specific Gravity
63-12 - pH
63-14 - Oxidizing or Reducing Action
63-15 - Flammability
63-16 - Explodability
63-17 - Storage Stability
63-18 - Viscosity
63-19 - Miscibility
Compos i t ioni/
MP
MP
MP
MP
MP
MP
MP
MP
MP
MP
MP
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
No
No
No
No
No
No
No
No
No
No
No
Must Additional
Data Be Submitted
Bibliographic Under FIFRA Section
Citation 3(c)(2)(B)?2/
Yes
Yes
Yes
Yes
No5/
Yes
Yes
Yes
Yes
Yes4/
Yes4/
Other Requirements:
64- 1 - Submittal of samples
N/A
N/A
No
- 86 -
-------
TABLE D
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NOS.
2749-292 (95% T), 1812-262 (95% T), 39511-5 (98% T) AND 11603-11 (80% FI).
158.120 Product Chemistry (continued)
I/ Composition: MP = Manufacturing-use product, T = Technical product, FI = Formulated Intermediate.
2/ Data must be submitted no later than six months after receipt of this guidance package.
3/ Nitrosamine data were submitted for the 80% FI (EPA Reg. No. 11603-11) only.
^/ Not required if the manufacturing-use products are solid at room temperature.
.=!/ Since Simazine is practically insoluable in water no pH is required.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 87 -
-------
TABLE E
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NO. 100-541 (97% T)
Data Requirement
Compos itionV
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Mate-
rials and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples
62-2 - Certification of Ingredient Limits
62-3 - Analytical Methods to
Verify Certified Limits
MP
MP
MP
MP
MP
MP
Yes
Partially
No
No
Partially
Partially
00023955
GS-650070-1
GS-650070-2
GS-650070-5
GS-650070-6
00023955
GS-650070-5
GS-650070-6
00023955
GS-650070-2
GS-650070-5
GS-650070-6
00023955
GS-650070-2
GS-650070-5
No
Yes
Yes
Yes
Yes
Yes
- 88 -
-------
TABLE E
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NO. 100-541 (97% T)
rl
j
Data Requirement
158.120
Product Chemistry (continued)
Compos it ion!/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Must Additional
Data Be Submitted
Bibliographic Under FIFRA Section
Citation 3(c) (2) (B)?2/
j Physical and Chemical Characteristics
i
-! 63- 2 -
63- 3 -
! 63- 4 -
i
63- 7 -
i 63-12 -
63-14 -
63-15 -
63-16 -
63-17 -
63-18 -
63-19 -
Color
Physical State
Odor
Density, Bulk Density, or
Specific Gravity
pH
Oxidizing or Reducing Action
Flammability
Explodability
Storage Stability
Viscosity
Miscibility
MP
MP
MP
MP
MP
MP
MP
MP
MP
N/A!/
N/A^/
Yes
Yes
Yes
Yes
No
No
No
No
Yes
N/A
N/A
GS-650070-6 No
GS-650070-6 No
GS-650070-6 No
GS-650070-6 No
No4/
Yes
Yes
Yes
GS-650070-6 No
No
No
Other Requirements;
64- 1 - Submittal of samples
N/A
N/A
No
- 89 -
-------
TABLE E
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NO. 100-541 (97% T)
158.120 Product Chemistry (continued)
!/ Composition: MP = Manufacturing-use product. T = Technical product.
2/ Data must be submitted no later than six months after receipt of this guidance package.
3/ Not required because the 97% technical product is solid at room temperature.
I/ Since Simazine is practically insoluable in water no pH is required.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 90 -
-------
TABLE F
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NO. 19713-59 (98% T)
Data Requirement
Composition!/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.120 Product Chemistry
Product Identity and Composition;
61-1 - Product Identity and Disclosure
of Ingredients MP
61-2 - Description of Beginning Mate-
rials and Manufacturing Process MP
61-3 - Discussion of Formation of
Impurities MP
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis of Product
Samples MP
62-2 - Certification of Ingredient Limits MP
62-3 - Analytical Methods to
Verify Certified Limits MP
Physical and Chemical Characteristics
63- 2 - Color MP
63- 3 - Physical State MP
63- 4 - Odor MP
Yes
Partially
No
No
Partially
Partially
No
No
No
GS-650070-3
GS-650070-10
GS-650070-3
GS-650070-3
GS-650070-10
GS-650070-3
No
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
- 91 -
-------
TABLE F
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING SIMAZINE, EPA REG. NO. 19713-59 (98% T)
Data Requirement
Composition!/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.120 Product Chemistry (continued)
63- 7
63-12
63-14
63-15
63-16
63-17
63-18
63-19
Other
64- 1
- Density, Bulk Density, or
Specific Gravity
- PH
- Oxidizing or Reducing Action
- Flammability
- Fxplodability
- Storage Stability
- Viscosity
- Miscibility
Requirements:
- Submittal of samples
MP
MP
MP
MP
MP
MP
MP
MA
N/A
No
No
NO
No
No
No
No
No
N/A
Yes
Noi/
Yes
Yes
Yes
Yes
Yesj!/
Yea?/
No
!/ Composition: MP = Manufacturing-use product. T = Technical product.
2/ Data must be submitted no later than six month after receipt of this guidance package.
3/ Not required if the technical product is solid at room temperature.
i/ Since Simazine is practically insoluable in water no pH is required.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
- 92 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
Composition!/
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
$158.125 Residue Chemistry
i
171-4 - Nature of Residue (Metabolism)
- Plants
PAIRA
Yes
- Livestock
PAIRA and plant
metabolites
Partially
00055672
GS-650070-12
GS-650070-13
GS-650070-14
GS-650070-15
GS-650070-16
GS-650070-17
GS-650070-77
GS-650070-78
00038297
GS-650070-18
GS-650070-19
GS-650070-20
GS-650070-21
GS-650070-77
GS-650070-79
GS-650070-80
GS-650070-81
GS-650070-82
No
- 93 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
Composition!/
Does EPA Have Data
to; Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
§158.125 Residue Chemistry (continued)
171-4 - Residue Analytical Method
- Plant residues
TGAI and metabolites Yes
- Animal residues
TGAI and metabolites Yes
171-4 - Storage Stability Data
PAI
Partially
GS-650070-22
GS-650070-24
GS-650070-28
GS-650070-29
GS-650070-30
GS-650070-32
GS-650070-33
GS-650070-34
GS-650070-36
GS-650070-37
GS-650070-38
GS-650070-39
GS-650070-22
GS-650070-23
GS-650070-25
GS-650070-26
GS-650070-27
GS-650070-31
GS-650070-34
GS-650070-35
GS-650070-36
GS-650070-37
GS-650070-40
GS-650070-41
GS-650070-42
No
No
Yesi/
- 94 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR SIMAZINE
Data Requirement
§158.125 Residue Chemistry (continued)
171-4 - Magnitude of the Residue-
Residue Studies for Each
Food Use
- Grapefruit
- Lemons
- Oranges
- Apples
- Pears
- Cherries
- Peaches
- Plums
- Blackberries
- Blueberries
- Boysenberries
- Cranberries
- Currants
- Dewberries
Compos i t ion!/
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Yes
Yes
Partially
No
Yes
Yes
No
Yes
Yes
Partially
Yes
Yes
Yes
Yes
- 95 -
Bibliographic
Citation
GS-650070-43
GS-6 50070-44
GS-650070-45
GS-650070-46
GS-650070-47
GS-650070-48
GS-650070-49
GS-650070-50
GS-650070-51
GS-650070-52
GS-650070-53
GS-650070-54
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
No
No
Yesjy
Yes!/
No
No
Yes!/
No
No
Yes§/
NO
No
No
No
-------
• TABLE A
GENERIC DATA REQUIREMENTS FDR SIMAZINE
Data Requirement
§158.125 Residue Chemistry
171-4 - Magnitude of the Residue-
Residue Studies (cont'd)
- Grapes
- Loganberries
- Raspberries
- Strawberries
- Almonds
- Filberts
- Macadamia Nuts
- Pecans
- Walnuts
- Corn
- Corn Forage and Fodder
(Field & Sweet Corn)
- Bermuda grass
- Grasses
- Alfalfa
Compos itionl/
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Partially
' Yes
Partially
N/A
Yes
Yes
Yes
Yes
Yes
No25/
No25y
Partially
Partially
No
- 96 -
Bibliographic
Citation
GS-650070-55
GS-650070-56
GS-6 50070-57
GS-6 50070-58
GS-650070-59
GS-650070-60
GS-650070-61
GS-650070-62
GS-650070-63
GS-650070-64
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
Yesi/
No
YeslO/
Noi!/
No
No
No
Ngl2/
NO
Yesl3/
Yesli/
YeslV
YesJJV
Yes!!/
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
§158.125 Residue Chemistry
171-4 - Magnitude of the Residue-
Residue Studies (cont'd)
- Artichokes
- Asparagus
- Avocados
- Bananas
- Olives
- Sugarcane
- Potable Water
- Fish
- Meat, Milk, Poultry, and Eggs
Compos i t ion!/
TEP
TEP
TEP
TEP
TEP
TEP
EP
TGAI
TGAI
Does EPA Have Data
to Satisfy This
Requirement? (Yes,
No or Partially)
Partially
Partially
Partially
Yes
Partially
Partially
No
Yes
Partially
Bibliographic
Citation
GS-650070-65
GS-6 50070-66
GS-650070-67
GS-6 50070-68
GS-650070-69
GS-650070-70
GS-650070-71
GS-650070-72
GS-650070-73
GS-650070-74
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
Yes!**/
Yeslg/
Yes2?y
No
Yes!!/
Yes?!/
Yes!3/
NO
Yes!!/
GS-650070-75
GS-650070-76
- 97 -
-------
I/ Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active
ingredient, radio-labelled; PAI = Pure active ingredient, TEP = Typical end-use
product, EP = End-use product, N/A = Not Applicable.
2/ Data must be submitted no later than four years after receipt of this guidance
package.
3/ Additional data required: Studies which elucidate the metabolism of simazine
and its chloronetabolites G-28273 and G-28279 in poultry (including eggs)
and ruminants (including milk); if the metabolism of simazine and its
chloronetabolites in poultry or ruminants is found to differ significantly
from that in rats, a non-ruminant (swine) study will also be required.
j4/ Additional data required: (a) Data demonstrating the stability of simazine
and its metabolites G-28273 and G-28279 in or on plant samples stored at
freezing temperatures for intervals up to about one year, since samples are
stored for this length of time prior to analysis, (b) Data demonstrating
the stability of simazine metabolites G-28273 and G-28279 in or on fish and
mammalian samples stored at freezing temperatures for intervals up to about
one year, since samples are stored for this length of time prior to analysis.
5/ Additional data required: (a) A single application with one of the WP
formulations at test locations in FL, TX, and CA or AZ. Residues of simazine
and metabolites G-28273 and G-28279 in or on whole oranges must be determined.
(b) If residues are found in whole oranges, then a fractionation study will
be required to determine residues in dried pulp, peel, oil, molasses, and juice.
6/ Data required: (a) A single directed application with one of the WP
formulations at 4 Ib. ai/A at test sites located in NY, MI, and WA. Residues
of simazine and metabolites G-28273 and G-28279 in or on apples must be
determined, (b) If residues are found in apples, then a processing study
is required to determine residues in pomace (wet and dry) and juice.
7/ Data required: A single directed-spray application with one of the WP
formulations at 4 Ib. ai/A at test sites located in CA, TX, MO, and
representative production areas east of the Mississippi River, including SC
or GA. Residues of simazine and metabolites G-28273 and G-28279 must be
determined in peaches.
8/ Additional data required: A single directed application with one of
the WP formulations at 4 Ib. ai/A at test sites located in MI, NJ, and ME.
Residues of simazine and metabolites G-28273 and G-28279 in or on blueberries
must be determined.
- 98 -
-------
9/ Additional data required: (a) A single directed-spray application with one
of the WP formulations at 4.8 Ib. ai/A at test sites in CA, MI, and NY.
Residues of simazine and metabolites G-28273 and G28279 in or on grapes must
be determined, (b) If residues are detected in or on grapes then residues
in juice, raisins and raisin waste, and pomace (wet and dry) must be determined.
10/ A single directed application with one of the WP formulations at 4 Ib. ai/A
at test sites in OR and WA. Residues of simazine and metabolites G-28273
and G-28279 in or on raspberries must be determined.
ll/ Data requirements for tolerance waived for strawberries, because the maximum
registered application rate is considerably less when compared with most
other group members.
12/ Tolerance established at 0.1 ppm. No additional data are required for this
commodity.
13/ Corn, fresh (including sweet corn kernels plus cobs with husks removed) and
corn grain. Additional data required: (a) Single aerial or ground
applications of either the 4 Ib./gal. fluid concentrate or one of the WP
formulations at 4 Ib. ai/A. Residues of simazine and metabolites G-28273
and G-28279 must be determined in fresh corn and corn grain, (b) If residues
are found in grain, then a fractionation study is required to determine
residues in corn oil (crude and refined), milled products, and cannery
waste (sweet corn only).
_!£/ Additional data required: Single aerial or ground applications of either
the 4 Ib./gal fluid concentrate or one of the WP formulations at 4 Ib.
ai/A. Residues of simazine and metabolites G-28273 and G-28279 must be
determined in corn forage and fodder.
15/ Additional data required: Residues of intact simazine and its metabolites
G-28273 and G-28279 must be determined in Bermuda grass forage and hay
following postemergence applications of one of the WP formulations. Forage
must be sampled 30 and 50 days following applications made at 2.4 and 3.2
Ib. ai/A, respectively; hay must be sampled at 60 and 90 days, respectively.
- 99 -
-------
16/ Additional data required: Residues of intact simazine and its metabolites
G-28273 and G-28279 must be determined on forage and hay of orchard grass
and tall fescue following postemergence applications of one of the WP
formulations at 2 Ib. ai/A; forage and hay must be sampled 30 and 60 days
17/ Data required: (a) Residues of intact simazine and its metabolites G-
28273 and G-28279 must be determined in or on seed, forage and hay of
alfalfa following applications of one of the WP formulations at 1.6 Ib.
ai/A; forage and hay must be sampled 30 and 60 days following treatment,
respectively, (b) If detectable residues are found in alfalfa seed, a
processing study will be required to determine residues occurring in meal.
18/ Additional data required: A single directed spray application with one of
the WP formulations at 4 Ib. ai/A. Residues of simazine and metabolites G-
28273 and G-28279 in or on artichokes must be determined.
19/ Additional data required: A single directed application with one of the WP
formulations at 4 Ib. ai/A; sampling intervals should include 0, 3, 7 and
10 days posttreatment. Residues of simzaine and metabolites G-28273 and
G-28279 in or on asparagus must be determined. Test locations should include
CA, MI, and WA.
20/ Additional data required: A single directed application (broadcast or
band) with one of the WP formulations at 4 Ib. ai/A at test sites located
in CA. Residues of simazine and metabolites G-28273 and G-28279 in or on
avocados must be determined.
21/ Additional data required: (a) A single directed application with one of
the WP formulations at 4 Ib. ai/A. Residues of simazine and its metabolites
G-28273 and G-28279 in or on olives must be determined, (b) If residues are
found in olives, then a processing study will be required to determine
residues in olive oil.
- 100 -
-------
22/ Additional data required: (a) A single preemergence and at least two
postemergence (one must be broadcast over the crop) treatments with one of
the WP formulations at 4 Ib. ai/A application at an interval schedule
setting the final postemergence application just prior to close-in (3.5
months before harvest). Residues of simazine and its metabolites G-28273
and G-28279 in or on sugarcane and sugarcane fodder must be determined. To
insure adequate geographic representation, tests should be conducted in Fl
and LA. (b) If residues are found in sugarcane, then a processing study
will be required for molasses, sugar, and bagasse.
23/ See Agency's revised policy on pesticide residues in drinking water published
in Federal Register Vol. 47, No. 115, June 15, 1982, Proposed Rules.
24/ Additional data required: (a) A feeding study with poultry fed simazine
per se and its two chlorcmetabolites individually at levels of Ix, 3x and
lOx the highest expected dietary intake by poultry. (Appropriate dosage
levels for feeding of metabolites connot be determined until sufficient
metabolite residue data for feed items have been received.) In this study
tissues and eggs must be analyzed for simazine per se, its two chloroplant-
metabolites, and any signficant animal metabolites found in the poultry
metabolism study requested under "Nature of the Residues in Animals." (b)
Depending upon the results of the requested animal metabolism study with
ruminants, a feeding study with ruminants may be needed where animals are
fed the two chlorcmetabolites individually at levels of Ix, 3x and lOx the
highest expected dietary intake by ruminants. In this feeding study,
residue levels of simazine plant and animal metabolites of toxicological
concern (if present as determined by the ruminant metabolism study) must
be determined in the milk, fat, meat and meat byproducts of ruminants.
25/ Sufficient data are not available to assess the adequacy of the tolerances
in covering residues resulting from the maximum registered rate in label
directions. The methodolgy used is not adequate for corn analyses due to
the high, yet inconsistent, background levels observed in check samples.
- 101 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
Use V
ConpositionV Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliographic
No or Partially) Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.130 Environmental Fate
DEGRADATION STUDIES-LAB;
161-1 - Hydrolysis
Photodegrada t ion
161-2 - In Water
161-3 - On Soil
161-4 - In Air
METABOLISM STUDIES-LAB;
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
162-4 - Aerobic Aquatic
MOBILITY STUDIES;
163-1 - Leaching and
Adsorption/Desorption
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
TGAI or PAIRA A,B,D,G,H
TGAI or PAIRA A,B,D,G
TGAI or PAIRA A4/ G
TGAI or PAIRA A
TGAI or PAIRA A,B,G,H
TGAI or PAIRA A
TGAI or PAIRA D,G
TGAI or PAIRA D
TGAI or PAIRA A,B,D,G,H
TEP
TEP
A
A
Yes
No
No
N/A
Partially
Yes
No
No
Partially
N/A
N/A
00027856
00027881
00040664
00027862
00027857
00001450
00044017
00027134
No
Yes IV
Yes IV
No /
No
Yes
Yes
Yes7_/17/
NoV
NO5/
- 102 -
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
158.130 Environmental Fate
(Continued)
DISSIPATION STUDIES-FIELD:
164-1 - Soil
164-2 - Aquatic
164-3 - Forestry
164-4 - Combination and
Tank Mixes
164-5 - Soil, Long-term
ACCUMULATION STUDIES:
165-1 - Rotational Crops
(Confined)
165-2 - Rotational Crops
(Field)
165-3 - Irrigated Crops
165-4 - In Fish
165-5 - In Aquatic Non-
Target Organisms
Use V
Compos itionV Pattern
TEP A,B,H
TEP D
TEP G
TEP N/A
TEP A
PAIRA A
TEP A
TEP A
TGAI or PAIRA A,B,D,G
TEP D,G
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliographic
No or Partially) Citation
Partially .
Partially
No
N/A
No
No
No
No
Yes
Yes
00027859
00065585
00025413
00023992
00025412
00043668
00043670
00023366
00027984
00025444
00027983
00027985
00034709
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
Yes^/16/
YesV
Yes
NoW
YesH/
Yes^/
Yes^/
Yesl3/
No
No*5/
Subpart K Re-entry
N/A
N/A No
- 103 -
-------
I/ Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active ingredient, radiolabelled;
~~ TEP = Typical end-use product. N/A - Not Applicable.
2/ The use patterns are coded as follows: A=Terrestrial, Food Crop; B=Terrestrial, Non-Food; C=Aquatic, Food Crop;
D=Aquatic, Non-Food; E=Greenhouse, Food Crop; F=Greenhouse, Non-Food; OForestry; H=Domestic Outdoor; I=Indoor.
3/ Data must be submitted no later than Four years after receipt of this guidance package.
4/ Data are required to support uses where simazine is not soil incorporated.
J>/ Data are not required because of the low vapor pressure of simazine.
6/ Data are needed for incubation periods of up to one year to fully delineate the patterns of formation and
decline of simazine degradates and to identify any additional products which may form.
7/ Data are needed on the leaching of simazine soil degradation products including adsorption/desorption studies.
B/ Data are required on the dissipation of simazine products representing each formulation category and the formation
and decline of degradates in soils treated at maximum label rates to support each use and major geographical use area.
Data on the dissipation of simazine in silt loam (NE, NY, OH) and fine sandy loam (CA) applied as wettable powder (WP)
or soluable concentrate/liquid (SC/L) (NE) are acceptable.
9/ Data on the dissipation of simazine in pond water in New York and Nebraska are acceptable. Additional data are
required on the dissipation of simazine in the soil/sediment phase of the aquatic environment, and on the formation
and decline of degradates in the aquatic environment. Data are also needed to support all other aquatic and aquatic
impact use including but not limited to drainage ditch banks, swimming pools and cooling water systems.
10/ Data requirements for combinations and tank mixes are not necessary for the purposes of this standard.
ll/ Data are required to support uses on field or vegetable crops if data from 162-1 or 164-1 indicate that 50%
dissipation of residues will not occur before a subsequent application to the same use site.
12/ For crops rotated on treated areas either of the following will apply: (a) A tolerance must be obtained for the
rotated crop, (b) Data must be provided to determine time intervals at which crops planted on treated
areas will be free of pesticide residues.
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13/ In instances where water frcm treated drainage ditches or flood irrigated orchards becomes contaminated with pesticide
residues, any one of the following will apply: (a) A tolerance must be obtained for any crop exposed to contaminated
water, (b) The product label must include a restriction against the use of water containing pesticide residues on
crops grown for food or feed, (c) Data must be provided to demonstrate conditions under which drainage water frcm
treated drainage ditches or flood irrigated orchards can be used on crops without resulting in illegal plant residues.
14/ Not applicable. Data to support the establishment of reentry protection standards are not required because the
Agency has determined, based on use patterns and available toxicology data for simazine that the criteria in
§158.140 are not met.
15/ Additional data are not required since laboratory studies indicate that simazine does not accumulate
significantly in fish tissue.
JL6/ Data must be submitted no later than two years after receipt of this guidance package.
17/ Data must be submitted no later than six months after receipt of this guidance package.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
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TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINF.
Does EPA Have Data Must Additional
to Satisfy This Data be Submitted
Use Requirement? (Yes, Bibliographic Under FIFRA Section
Data Requirement Composition1/ Pattern2/ No or Partially) Citation 3(c) (2) (B)?V
§158.135 Toxicology
ACUTE TESTING
81-1 - Oral LDso- Rat TGAI A B C D H
81-2 - Dermal LDso TCAI A B C D H
81-3 - Inhalation LCso~ Rat TGAI A B C D H
81-4 - Primary Skin Irritation TGAI A B C D H
81-5 - Primary Eye Irritation TGAI A B C D H
81-7 - Acute Delayed
Neurotoxicity - Hen
SUBCHRONIC TESTING
82-1 - 90 Day Feeding
Rodent, Non-Rodent TGAI A B C D H
82-2 - 21 Day Dermal TGAI A B C D H
82-3 - 90 Day Dermal
82-4 - 90 Day Inhalation - Rat
Yes
YES
No
Yes
Yes
N/A
NO
Yes
N/A
N/A
GS-650070-83 No
00023965 No
Yes
00023965 No
00023965 No
No
YESV
00057567 No
No
No
82-5 - 90 Day Neurotoxicity -
Hen/Mammal
N/A
No
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TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
CompositionV
Does EPA Have Data
Use to Satisfy This
Pattern2/ Requirement (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
S158.135 Toxicology
(Continued)
CHRONIC TESTING
83-1 - Chronic Toxicity -
2 species: Rodent
and Non-Rodent
83-2 - Oncogenicity Study -
2 Species: Rat and
Mouse Preferred
83-3 - Teratogenicity -
2 Species
83-4 - Reproduction -
2 - Generation
TGAI
TGAI
TGAI
TGAI
A B C D H
A B C D H
A B C D H
A B C D H
No
No
No
Yes (Rat)
00023365
00080631
Yes
Yes
Yes
No
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TABLF A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
Compos i t ionV
Use
Pattern2/
Does EPA Have Data
To Satisfy This
Requirement (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
§158.135 Toxicology
(Continued)
MUTAGENICITY TESTING
84-2 - Gene Mutation
84-2 - Chromosomal Aberration
84-2 - Other Mechanisms Of
Mutagenicity
SPECIAL TESTING
85-1 - General Metabolism
85-2 - Domestic Animal Safety
TGAI
TGAI
TGAI
PAI or
PAIRA
A B C D H
A B C D H
A B C D H
A B C D H
No
No
No
Partially
N/A
00080633, 00080635,
OOOP0632
Yes
Yes
Yes
YesV
No
I/ Composition: TGAI = Technical grade of active ingredient; PAI = Pure active ingredient; PAIRA = Pure active
ingredient, radiolabelled; CHOICE = Choice of several test substances determined on a case-hy-case basis.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic,
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H =
Dcrnestic Outdoor; I = Indoor.
2/ Data must be submitted no later than six months for acute data, and 48 months for remainder of data except for data
in response to the previously issued Data Call-in Notice, 90 Day Feeding Rodent and Non-Rodent, and General Metabolism.
4/ Data must be submitted no later than one year after receipt of this guidance package.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
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WILDLIFE AND AQUATIC ORGANISMS
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement Composition I/
S158.145
Aquatic
Wildlife and
Organisms
Does EPA Have Data
To Satisfy This
Use 2/ Requirement? (Yes,
Pattern No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
AVIAN AND MAMMALIAN TESTING
71 - 1 -
71 - 2 -
71 - 3 -
71 - 4 -
71 - 5 -
Avian Oral LDso TGAI
Avian Dietary LCcn TGAI
Wild Mammal Toxic ity TGAI
Avian Reproduction TGAI
Simulated and Actual
Field Testing -
Mammals and Birds
A,B,D,G Yes
A,B,D!/,G yes
N/A N/A
B Partially^/
N/A N/A
00072798*
00043678*
00034769**
00043672**
GS-650070-84**
00043678*
No
No
No
Yes
No
AQUATIC ORGANISM TESTING
72 - 1 -
72 - 2 -
Freshwater Fish 1X50 TGAI
TEP
Acute LC50 Freshwater TGAI
I nvertebra tes TEP
A,B,G, Yes
D Partially^/
A,B,G, Yes
D Yes
00043666*
00043668**
00025438*
00033309**
00026299**
00034214**
GS-650070-85**
00043676*
No
Yes
No
No
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WILDLIFE AND AQUATIC ORGANISMS
TABLE A
GENERIC DATA REQUIREMENTS FDR SIMAZINE
Data Requirement
Composition I/
Does EPA Have Data
To Satisfy This
Use .?/ Requirement? (Yes,
Pattern No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
§158.145 Wildlife and
Aquatic Organisms
(continued)
72 - 3 - Acute LCso Estuarine TGAI
and Marine Organisms
72 - 4 - Fish Early Life
Stage and Aquatic
Invertebrate Life-Cycle
72 - 5 - Fish - Life-Cycle
72-6
TGAI
A,B,G
B,D
Aquatic Organism
Accumulation
72 - 7 - Simulated or Actual
Field Testing -
Aquatic Organisms
TEP
B,D
Yes
Yes
N/A
N/A
Partially
00023331*
00043667**
00043677**
00043676*
00025433
**
No
No
No
No
Noil/
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WILDLIFE AND AQUATIC ORGANISMS
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
I/ Use 2/ Requirement? (Yes,
Pattern No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
§158.155 Nontarget Insect
NONTARGET INSECT TESTING -
POLLINATORS;
141 - 1 - Honey bee acute
contact
TGAI
141 - 2 - Honey bee - toxicity
of residues on
foliage
TEP
141 - 3 - Wild bees important in
alfalfa pollination -
toxicity of residues
on foliage TEP
141 - 4 - Honey bee subacute
feeding study
141 - 5 - Field testing for
pollinators
A,B
A,B
A,B
fReserved].Z/
TEP
A,B
Yes
00036935*
No
No
No
No!/
NoiPy
NO
NO?/
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WILDLIFE AND AQUATIC ORGANISMS
TABLE A
GENERIC DATA REQUIREMENTS FOR SIMAZINE
Does EPA Have Data Must Additional
To Satisfy This Data Be Submitted
I/ Use 2/ Requirement? (Yes, Bibliographic Under FIFRA Section
Data Requirement Composition Pattern No or Partially) Citation 3(c) (2)
§158.155 Nontarget Insect
(continued)
NONTARGET INSECT TESTING -
AQUATIC INSECTS;
142 - 1 - Acute toxicity to
aquatic insects [Reserved]8/
142 - 2 - Aquatic Insect
life-cycle study [Reserved]]}/
142 - 3 - Simulated or actual
field testing for
aquatic insects [Reserved]*}/
143 - 1 - NONTARGET INSECT TESTING -
thru PREDATORS AND PARASITES
143-3 [Reserved ]8/
- 112 -
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_]_/ Conposition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry;
H = Domestic Outdoor; I = Indoor.
3/ Data must be submitted no later than four years after receipt of the guidance package.
4/ Cooling tower use requires only one dietary study.
5/ One study (waterfowl) was submitted, another reproductive study is needed (upland gamebird). The waterfowl
study may need to be repeated pending results of the upland gamebird study.
6/ One study (warmwater species) was submitted; another is required on a coldwater species.
7/ [Reserved] Requirement reserved pending development of test methodology.
jV [Reserved! Pending decision as to whether data requirement should he established.
9/ As first tier (acute contact) test indicated low toxicity to honey bees, further testing is not required.
10/ Required only when product is intended for foliar application to seed alfalfa.
ll/ These field studies are not presently required, but could be based on the results of formulated product testing.
N/A = Not Applicable: Data requirement is not necessary for purposes of this standard.
* = Study can stand alone to fulfill guideline requirements.
** = Study does not fulfill data requirements and must be cited in conjunction with other studies
to fulfill data requirements.
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III. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Note: This chapter applies only to manufacturing-use products,
not end-use products.
A necessary first step in determining which statements must
appear on your product's label is the completion and submission
to EPA of product-specific data* listed on the form entitled
"Product Specific Data Report" (EPA Form 8580-4, Appendix III-l)
to fill "gaps" identified by EPA concerning your product. Under
the authority of FIFRA Section 3(c)(2)(B), EPA has determined
that you must submit these data to EPA in order to register or
reregister your product(s). All of these data must be submitted
not later than six months after you receive this guidance document,
"Product-Specific Data Requirements for Manufacturing-Use
Products" appearing in Table B permit you to determine which
product-specific data you must submit. This can be done by
examining the entries in the column of those tables entitled
"Must Data Be Submitted Under §3(c)(2)(B)."
V Product specific data pertains to data that support the
formulation which is marketed; it usually includes product
chemistry data and acute toxicology data.
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IV. SUBMISSION OF REVISED LABELING AND PACKAGING INFORMATION
Note: This chapter applies only to manufacturing-use products,
not end-use products. x
The Agency requires applicants for registration or reregistra-
tion to ensure that each label (1) contains accurate, complete,
and sufficient instructions and precautions, reflecting the
results of data concerning the product and its ingredients, and
(2) incorporates labeling format and terminology which are suffi-
ciently standardized to avoid user confusion.
As part of your application, you will be required to submit
draft labeling consistent with: applicable product-specific
data; the precautionary statements and use directions; and the
regulations concerning classification [40 CFR §162.11(c)], pack-
aging [40 CFR §162.16] ,'and labeling [40 CFR §162.10, Appendix
IV-1 an IV-2], as indicated by the following paragraphs of this
chapter of the guidance document.
You will be informed later when you must submit the revised
labeling set forth in this guidance package.
A. Label Contents
40 CFR §162.10 (Appendix IV-1) requires that certain spe-
cific labeling statements must appear at certain locations
on the label. This is referred to as format labeling.
Specific label items listed below are keyed to Tables D, E,
and F (Appendix IV-2).
Item 1. PRODUCT NAME - The name, brand, or trademark is
required to be located on the front panel, preferably centered
in the upper part of the panel. The name of a product will
not be accepted if it is false or misleading. See Appendix
IV-1. [40 CFR §162.10(b)]
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
See Appendix IV-1. [40 CFR §162.10(c)]
Item 3. NET CONTENTS - A net content statement is required
on all labels. The preferred location is the bottom of the
front panel immediately above the company name and address,
or at the end of the label text. The net contents must be
stated in terms of weight, expressed as avoirdupois pounds
- 115 -
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and ounces, and stated in terms of the largest suitable unit,
i.e., "1 pound 10 ounces" rather than "26 ounces." In
addition to the required units specified, net contents may be
expressed in metric units. See Appendix IV-1. [40 CFR
§162.10(d)]
Item 4. EPA REGISTRATION NUMBER - The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase "EPA Registration No.," or "EPA
Reg. No." The registration number must be set in type of a
size and style similar to other print on that part of the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency. See Appendix IV-1.
[40 CFR §162.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment
number, preceded by the phrase "EPA Est." is the final estab-
lishment at which the product was produced, and may appear
in any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of
the package if the EPA establishment registration number on
the immediate container cannot be clearly read through such
wrapper or container. See Appendix IV-1. [40 CFR §162.10(f)]
Item 6. INGREDIENT STATEMENT - An ingredient statement
is required on the front panel and must contain the name and
percentage by weight of each active ingredient and the total
percentage by weight of all inert ingredients. The preferred
location is immediately below the product name. The ingredient
statement must run parallel with, and be clearly distinguished
from, other text on the panel. It must not be placed in the
body of other text. See Appendix IV-1. [40 CFR 162.10(g)]
Item 6A. POUNDS PER GALLON STATEMENT - For liquid
agricultural formulations, the pounds per gallon of active
ingredient must be indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS - All labels
are required to have precautionary statements grouped together
on the front panel, preferably within a block outline. The
table below shows the minimum type size requirements on
various size labels, as set forth in the Regulations.
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Size of Label Signal Word as Re- "Keep Out of Reach
on Front Panel quired Minimum Type of Children"
in Square Inches Size All Capitals as Required
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - All labels are
required to have the statement "Keep Out of Reach of Children"
located on the front panel above the signal word except where
contact with children during distribution or use is unlikely.
See Appendix TV-1. [40 CFR §162. 10 (h) (1) (ii) ]
Item 7B. SIGNAL WORD - The signal word (Caution, Warning,
or Danger) is required on the front panel immediately below
the child hazard warning statement. See Appendix IV-1.
[40 CFR §162.10 (h) (l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, inhala-
tion, or dermal toxicity, the word "Poison" shall appear on
the label in red on a background of distinctly contrasting
color and the skull and crossbones shall appear in immediate
proximity to the word poison. See Appendix IV-1. [40 CFR
Item 7D. STATEMENT OF PRACTICAL TREATMENT - A statement
of practical treatment (first aid or other) shall appear on
the label of pesticide products in toxicity Categories I,
II, and III. See Appendix IV-1. [40 CFR §162.10(h) (1) (iii) ]
Item 7E. REFERRAL STATEMENT - The statement "See Side
(or Back) Panel for Additional Precautionary Statements" is
required on the front panel for all products, unless all
required precautionary statements appear on the front panel.
See Appendix IV-1. [40 CFR §162. 10(h) (1) (iii) ]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING - The
precautionary statements as listed below must appear together
on the label under the heading "PRECAUTIONARY STATEMENTS."
The preferred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the. three hazard warning statements must be headed by the
appropriate hazard title. See Appendix IV-1. [40 CFR §162.10
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Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a
hazard exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard, the
route(s) of exposure and. the precautions taken to avoid
accident, injury or damage. See Appendix IV-1. [40 CFR §162.10
Item SB. ENVIRONMENTAL HAZARD - Where a hazard exists to
non-target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. See Appendix IV-1. [40 CFR
Item 8C. PHYSICAL OR CHEMICAL HAZARD
1. Flammability statement . Precautionary statements
relating to f lammability of a product are required
to appear on the label if it meets the criteria in
Appendix IV-3. The requirement is based on the results
of the flashpoint determinations and flame extension
tests required to be submitted for all products .
These statements are to be located in the side/back
panel precautionary statements section, preceded by
the heading "Physical/Chemical Hazards." Note that
no signal word is used in conjunction with the flam-
mability statements.
2. Criteria for declaration of non-f lammability . The
following criteria will be used to determine if a
product is non-flammable:
a. A "non-flammable gas" is a gas (or mixture of
gases) that will not ignite when a lighted match
is placed against the open cylinder valve.
b. A " non-flammable liquid" is one having a flash-
point greater than 350°F (177°C) as determined
by the method specified in 40 CFR §163. 61-8(c) (13)
(ii) of Subpart D.
c. A "non-flammable aerosol" is one which meets the
following criteria:
i. The flame extension is zero inches, using the
method specified in 40 CFR §163. 61-8(c) (13 ) (ii) ;
ii. There is no flash back; and
iii. The flashpoint of the non-volatile liquid
component is greater than 350 °F (177°C),
determined by the method specified in 40 CFR
§163.6l-8(c)(l3)(i).
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3. Declaration of non-flammability. Products which meet
the criteria for non-flammability specified above may
bear the notation "non-flammable" or "nonflammable
(gas, liquid, etc.)" on the label.
It may appear as a substatement to the ingredients
statement, or on a back or side panel, but shall not
be highlighted or emphasized (as with an inordinately
large type size) in any way that may detract from
precaution.
4. Other physical/chemical hazard statements. When
chemistry data submitted in accordance with 40 CFR
§163.61-10(c) demonstrate hazards of a physical or
chemical nature other than flammability, appropriate
statements of hazard will be prescribed. Such
statements may address hazards of explosivity,
oxidizing or reducing capability, or mixing with
other substances to produce toxic fumes.
Item 9. MISUSE STATEMENT - The following statement is
required on your label: "It is a violation of Federal law to
use this product in a manner inconsistent with its labeling."
See Appendix IV-1. [40 CFR §162.10(1)(2)(ii)]
Item 10A. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage and disposal statements. These
statements are developed for specific containers, sizes, and .
chemical content. Make certain that the statement you use
pertains specifically to your product. These instructions
must be grouped and appear under the heading "Storage and
Disposal" in the directions for use. This heading must be
set in the same type sizes as required for the child hazard
warning. Refer to Appendix IV-5 for the latest specific
storage and disposal product label statements.
Item 10B. DIRECTIONS FOR USE - Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate to
protect the public from fraud and from personal injury and to
prevent unreasonable adverse effects on the environment. See
Appendix IV-1. [40 CFR §162.10]
B. Collateral Information
Bulletins, leaflets, circulars, brochures, data sheets,
flyers, and other graphic printed matter which is referred to
on the label or which is to accompany the product are termed
collateral labeling. Such labeling may not bear claims or
representations that differ in substance from those accepted
in connection with registration of the product. It should be
made part of the response to this notice and submitted for review.
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V. INSTRUCTIONS FOR SUBMISSION
All applications prepared in response to this Notice should
be addressed as follows:
[Product Manager] PM-23
Phone No. (703) 557-1830
Registration Division (TS-767)
Office of Pesticide Programs
Environmental Protection Agency
Washington, D.C. 20460
For each product for which continued registration is desired:
1. Within 90 days from receipt of this document, you must
submit the "FIFRA Section 3(c)(2)(B) Summary Sheet" EPA
Form 8580-1. Refer to Appendix II-2 with appropriate
attachments.
2. Within 6 months from receipt of this document registrants
must submit:
a. Confidential Statement of Formula, EPA Form 8570-4.
b. Product Specific Data Report, EPA Form 8580-4 (Appendix
III-l).
c. Two copies of any required product-specific data.
3. Within the time set forth in Table A, all generic data
must be submitted by the affected registrant(s).
Note; If for any reason any required test is delayed or aborted
so that meeting the agreed submission time will be delayed,
notify the Product Manager listed above.
You will be informed at a later date when you must submit your
Application for Amended Pesticide Registration (EPA Form 8570-1)
and the revised labeling set forth in this guidance package.
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Appendix II-l
Guide to Use of This Bibliography
CONTENT OF BIBLIOGRAPHY. This bibliography contains
citations of all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources for studies in this
bibliography have been the body of data submitted to EPA
and its predecessor agencies in support of past regulatory
decisions. Selections from other sources including the
published literature, in those instances where they have
been considered, will be included.
UNITS OF ENTRY. The unit of entry in this bibliography
is called a "study." In the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
"studies" generally have a distinct title (or at least a
single subject), can stand' alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study.
IDENTIFICATION OF ENTRIES. The entries in this bibliography
are sorted numerically by "Master Record Identifier," or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It is not related to the six-digit "Accession Number"
which has been used to identify volumes of submitted
studies; see paragraph 4(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late in the review may be preceded by a nine-character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number is
also to be used whenever specific reference is needed.
FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards of the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
-------
Appendix II-l
(continued)
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four-digit date is followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??), the Agency was unable to determine
or estimate the date of the document.
c. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets.
d. Trailing Parentheses. For studies submitted to the
Agency in the past, the trailing parentheses include
(in addition to any self-explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
"received."
(2) Administrative Number. The next element,
immediately following the word "under," is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission.
(3) Submitter. The third element is the submitter,
following the phrase "submitted by." When
authorship is defaulted to the submitter, this
element is omitted.
(4) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA accession number of the volume
in which the original submission of the study
appears. The six-digit accession number follows
the symbol "CDL," standing for "Company Data
Library." This accession number is in turn
followed by an alphabetic suffix which shows the
, relative position of the study within the volume.
For example, within accession number 123456, the
first study would be 123456-A; the second, 123456-
B; the 26th, 123456-Z; and the 27th, 123456-AA.
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- 1 -
00001450 Helling, C.S.; Turner, B.C. (1968) Pesticide mobility: Determin-
ation by soil thin-layer chromatography. Method dated Nov 1,
1968. Science 162(?/Nov):562-563. (Also In unpublished submis-
sion received Feb 17, 1970 under 352-324; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:002972-B)
00023331 Sleight, B.H., III (1973) Acute Toxicity of Simazine to Pink Shrimp
(Penaeus duorarum) and Mud Crab (Neopanope texana).
(Unpublished study received Apr 25, 1973 under unknown admin.
no., prepared by Bionomics, Inc., submitted by Ciba-Geigy Corp.,
Greensboro, N.C.; CDL:129174-A)
00023365 Johnston, C.D.; Cronin, M.T.I. (1965) Simazine: Three-Generation
Reproduction Study in the Rat. (Unpublished study received Sep
16, 1965 under 5F0447; prepared by Woodard Research Corp., sub-
mitted by Geigy Chemical Corp., Ardsley, N.Y.; CDL:090489-B)
00023366 Simoneaux, B.; Sy, A. (1972) Simazine Metabolism in an Aquatic Sys-
tem: Report No. GAAC-72121. (Unpublished study received Dec 13,
1972 under OF0996; submitted by Geigy Chemical Co., Ardsley,
N.Y.; CDL:091715-B)
00023955 Ciba-Geigy Corporation (1977) Chemical Data Section for Simazine.
(Unpublished study received Apr 27, 1977 under 100-541; CDL:
229606-A)
00023965 Palazzolo, R.J. (1965) Report to Geigy Chemical Corporation: Acute
Toxicity Studies on Simazine SOW. (Unpublished study received
Aug 31, 1965 under 100-437; prepared by Industrial Bio-Test Lab-
oratories, Inc., submitted by Ciba-Geigy Corp., Greensboro,
N.C,; CDL:100969-A)
00023992 Larsen, H.; Sutton, D.L.; Eaton, A.R.; et al. (1966) Summary of
Residue Studies—Simazine SOW. (Unpublished study received Mar
8, 1966 under 100-437; prepared in cooperation with U.S. Fish
and Wildlife Service, Fish Control Laboratory and others, sub-
mitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:101141-A)
00025412 LeBaron, H.M. (1970) Fate of Simazine in the Aquatic Environment:
Report No. GAAC-70013. (Unpublished study received May 12,
1970 under OF0996; submitted by Geigy Chemical Co., Ardsley,
N.Y.; CDL:091712-A)
00025413 Flanagan, J.H.; Foster, J.R.; Larsen, H.; et al. (1968) Residue
Data for Simazine in Water and Fish. (Unpublished study re-
ceived May 12, 1970 under OF0996; prepared in cooperation with
Univ. of Maryland and others, submitted by Geigy Chemical Co.,
Ardsley, N.Y.; CDL:091712-D)
00025433 Gilderhus, P.A. (1969) Some Effects of Long-Term Exposure to Sima-
zine on Goldfish, Bluegills, and Aquatic Invertebrates. (Un-
published study received Mar 12, 1969 under OF0996; prepared
by U.S. Fish and Wildlife Service, Fish Control Laboratory,
submitted by Geigy Chemical Corp., New York, N.Y.; CDL:091713-D)
-------
- 2 -
00025438 Bellies, R.P.; Scott, W.; Knott, W. (1965) Simazine: Acute Toxicity
in Sunfish. (Unpublished study received Mar 12, 1969 under
OF0996; prepared by Woodard Research Corp., submitted by Geigy
Chemical Corp., New York, N.Y.; CDL:091713-K)
00025444 Kahrs, R.A.; Mattson, A.M. (1973) Residues of Simazine in Fish from
Ponds Treated with Simazine: Report No. GAAC-73048. (Unpublished
study received on unknown date under OF0996; submitted by
Ciba-Geigy Corp., Greensboro, N.C.; CDL:093305-B)
00026299 Beliles, R.P.; Scott, W.; Knott, W. (1965) Simazine: Acute Toxicity
in Goldfish. (Unpublished study received Mar 12, 1969 under
OF0996; prepared by Woodard Research Corp., submitted by Geigy
Chemical Corp, New York, N.Y.; CDL:091713-L)
00027134 Talbert, R.E.; Fletchall, O.H. (1965) The adsorption of sane s-
triazines in soils. Weeds 13(? ):46-52. (Also In unpublished
submission received Jul 19, 1978 under 201-403; submitted by
Shell Chemical Co., Washington, D.C.; CDL:234472-J)
00027856 Gold, B.; Balu, K.; Hofberg, A. (1973) Hydrolysis of Simazine in
Aqueous Solution: Report No. GAAC-73044. (Unpublished study re-
ceived Jul 17, 1978 under 100-541; submitted by Ciba-Geigy
Corp., Greensboro, N.C.; CDL:234454-B)
00027857 Keller, A. (1978) Degradation of Simazine (Gesatop(R) in Soil
under Aerobic/Anaerobic and Sterile/Aerobic conditions: Project
Report 05/78. (Unpublished study received Jul 17, 1978 under
100-541; prepared by Ciba-Geigy Corp., Greensboro, N.C.; CDL:
234454-D)
00027859 Martin, V.; Motko, L.; Gold, B.; et al. (1975) Simazine Residue
Tests: AG-A No. 1022. (Unpublished study including AG-A nos.
1154, 1154-III, 1184..., received Jul 17, 1978 under 100-541;
prepared in cooperation with Univ. of Missouri and others, sub-
mitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:234454-G)
00027862 Beynon, K.I.; Stoydin, G.; Wright, A.N. (1972) A Comparison
of the Breakdown of the Triazine Herbicides Cyanazine, Atrazine,
and Simazine in Soils and in Maize. Pesticide Biochemistry and
Physiology 2(?):153-161. (Also in unpublished submission
received Jul 17, 1978 under 100-541; submitted by Ciba-Geigy
Corp., Greensboro, N.C.; CDL:234455-B)
00027881 Walker, A. (1976) Simulation of herbicide persistence in soil.
Pesticide Science 7(? ):41-49. (Also in unpublished submis-
sion received Jul 17, 1978 under 100-541; submitted by Ciba-
Geigy Corp., Greensboro, N.C.; CDL:234455-AA)
00027983 Mayer, F.L., Jr. (1973) Residue Reports on Simazine in Fish:
AG-A No. 2899 I-III. (Unpublished study including letters
dated Jun 1, 1973 from P.A. Gilderhus to Jack Norton and Jun 13,
1973 from F.L. Mayer, Jr. to Arnold Mattson and AG-A no. 2900
I-III, received Jul 26, 1973 under OF0996; Prepared in coopera-
tion with U.S. Fish and Wildlife Service, Div. of Fishery
Research, Branch of Pest Control Research, submitted by Geigy
-------
- 3 -
Chemical Co., Ardsley, N.Y.; CDL:091716-B)
00027984 Gilderhus, P.A. (1973) Residue Reports on Simazine in Fish: AG-A
No. 2905 I-III. (Unpublished study including letter dated
Jun 1, 1973 from P.A. Gilderhus to Jack Norton and AG-A no. 2906
I-III, received Jul 26, 1973 under OF0996; prepared in coopera-
tion with U.S. Fish and Wildlife Service, Fish Control Labora-
tory, submitted by Geigy Chemical Co., Ardsley, N.Y.; CDL:
091716-C)
00027985 Ragsdale, D.W. (1973) Residue Reports on Simazine in Fish and
Water: AG-A No. 2940. (Unpublished study including letter
dated Jun 16, 1973 from M. Roderick to Dan W. Ragsdale and
AG-A no. 2941, received Jul 26, 1973 under OF0996; submitted
by Geigy Chemical Co., Ardsley, N.Y.; CDL:091716-D)
00033309 Sleight, B.H., III (1971) Bioassay Report: Acute Toxicity of Some
Ciba-Geigy Experimental Chemicals to Fathead Minnows (Pime-
phales pronelas. (Unpublished study received May 16, 1973
under 1769-234; prepared by Bionomics, Inc., submitted by NCH
Corp., National Chemsearch Div., Irving, Tex.; CDL:221976-N)
00034214 Swabey, Y.H.; Schenk, C.F. (1963) Report on Algicides and Aquatic
Herbicides. (Unpublished study received Jan 5, 1968 under 201-
118; prepared by Ontario, Water Resources Commission, submitted
by Shell Chemical Co., Washington, D.C.; CDL:000755-N)
00034709 Tweedy, B.C.; Walsh, D.F.; Mayer, F.L., Jr. (1974) Residues of
Simazine and Its Chloro-metabolites, G-28279 and G-28273 in
Fish from a Missouri Pond Treated with Simazine: Report No.
GAAC-74054. (Unpublished study including letter dated Jul 22,
1974 from F.L. Mayer, Jr. to Jack Norton, received on unknown
date under OF0996; prepared in cooperation with U.S. Fish and
Wildlife Service, Fish-Pesticide Laboratory, submitted by
Ciba-Geigy Corp., Greensboro, N.C.; CDL:093305-A)
00034769 Hill, E.F.; Heath, R.G.; Spann, J.W.; et al. (1975) Lethal Dietary
Toxicities of Environmental Pollutants to Birds. By U.S. Fish
and Wildlife Service, Patuxent Wildlife Research Center. Wash-
ington, D.C.: U.S. FWS. (Special Scientific Report—Wildlife
No. 191; report no. 33423a; also in unpublished submission re-
ceived Mar 28, 1979 under 3125-236; submitted by Mobay Chemical
Corp., Kansas City, Mo.; CDL:237905-B)
00036935 Atkins, E.L.; Greywood, E.A.; Macdonald, R.L. (1975) Toxicity of
Pesticides and Other Agricultural Chemicals to Honey Bees: Labo-
ratory Studies. By University of California, Dept. of Entomolo-
gy. ?: UC, Cooperative Extension. (Leaflet 2287; published
study.)
00038297 Bohme, C.; Bar, F. (1975) Breakdown of Triazine Herbicides in the
Animal Organism. A translation of: Uher den Abbau von Triazin-
Herbiciden im Tierischen Organismus. (Unpublished study re-
ceived on unknown date under OF0996; prepared by Bundesgesund-
heitsamt, Max von Pettenkofer-Institute, Laboratorium fur
Ernahrungshygiene, submitted by Geigy Chemical Co., Ardsley,
N.Y.; CDL:093306-A)
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- 4 -
00040664 Beynon, K.I.; Stoydin, G.; Wright, A.N. (1972) A comparison of the
breakdown of the Triazine herbicides Cyanazine, Atrazine and Si-
mazine in soils and in maize. Pesticide Biochemistry and Physi-
ology 2(2):153-161. (Also In unpublished submission received
Jul 19, 1978 under 201-403; submitted by Shell Chemical Co.,
Washington, D.C.; CDL:234476-D)
00043666 Kuc, W.J. (1976) Acute Toxicity of Simazine Technical, Batch #
FL-750336 to the Rainbow Trout, (Salmo gairdneri Richardson):
AES Project #7635-500. (Unpublished study received Apr 27, 1977
under 100-541; prepared by Union Carbide Corp., submitted by Ci-
ba-Geigy Corp., Greensboro, N.C.; CDL:229607-W)
00043667 Cook, J.D.; Smith, B.W. (1976) Sensitivity of Striped Bass Finger-
lings to Simazine. (Unpublished paper presented at the National
Fish Culture Workshop; Jan 13-15, 1976, Springfield, Missouri;
Alabama, Game and Fish Div., unpublished study; CDL:229607-X)
00043668 Zak, F.; Hermann, W.D.; Sachsse, K. (1973) 56-Day Toxicity and Res-
idue Study of Simazine on Rainbow Trout (Salmo gairdneri):
Project No. Siss 1725. (Unpublished study received Apr 27, 1977
under 100-541; prepared by Ciba-Geigy, Ltd., Switzerland, sub-
mitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:229607-Y)
00043670 Sleight, B.H., III; Macek, K.J. (1972) Research Report: Continuous
Exposure of Bluegill (Lepomis macrochirus) to Simazine in
' Water: AG-A No. 2199. (Unpublished study including AG-A nos.
2199 II, 2199 II A, 2473..., received Apr 27, 1977 under 100-
541; prepared in cooperation with Bionomics, Inc., submitted by
Ciba-Geigy Corp., Greensboro, N.C.; CDL:229607-AA)
00043672 Beliles, R.P.; Scott, W.; Knott, W.; (1965) Simazine: Subacute Tox-
icity in Mallard Ducks. (Unpublished study received Apr 27,
1977 under 100-541; prepared by Woodard Research Corp., submit-
ted by Ciba-Geigy Corp., Greensboro N.C.; CDL.-229607-AF)
00043676 Mayer, F.L.; Sanders, H.O'. (1975) Effects of Aquazine(R) on Daph-
nids and Fathead Minnows under Continuous and Usage-Pattern Ex-
posures. Prelim, rept. (U.S. Fish and Wildlife Sen/ice, Fish-
Pesticide Research Laboratory, unpublished study; CDL:229607-AK)
00043677 Wright, L.S., Jr.; Beliles, R.P. (1966) Simazine: The Effect on
Shell Growth in Oysters. (Unpublished study received Apr 27,
1977 under 100-541; prepared by Woodard Research Corp., submit-
ted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:229607-AM)
00043678 Fink, R. (1974) Final Report: One-Generation Reproduction Study—
Mallard Ducks: Project No. 108-101. (Unpublished study received
Apr 27, 1977 under 100-541; prepared by Truslow Farms, Inc.,
submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:229607-AP)
00044017 Helling, C.S. (1971) Pesticide mobility in soils: II. Applications
of soil thin-layer chromatography. Soil Science Society of
America Proceedings 35:737-748. (Also In unpublished submission
received May 5, 1975 under 464-323; submitted by Dow Chemical
U.S.A., Midland, Mich.; CDL:221997-S)
-------
- 5 -
00055672 Ciba-Geigy Chemical Corporation (1971) Metabolism of S-Triazine
Herbicides. (Unpublished study including letter dated Dec 29,
1971 from J.R. Forsythe to Harold G. Alford, received Dec 29,
1971 under 100-437; CDL:231915-A)
00057567 Bier, C.B.; Oliveira, P.H. (1980) 21-Day Subacute Dermal Toxicity
Study in Albino Rabbits Administered Test Article Simazine:
Project No. 12017. (Unpublished study received Feb 26, 1981
under 100-437; prepared by Bio-Research Laboratories, Ltd.,
Canada, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:
244454-e)
00065585 Mattson, A.M.; Kahrs, R.A.; Murphy, R.T. (1969) Quantitative Deter-
mination of Triazine Herbicides in Soils by Chemical Analysis:
GAAC-69014. Method dated Mar 18, 1969. (Unpublished study re-
ceived Aug 26, 1977 under 100-496; submitted by Ciba-Geigy
Corp., Greensboro, N.C.; CDL:231423-B)
00072798 Fink, R. (1976) Final Report: Acute Oral LD50 - Mallard Duck:
Project No. 108-121. (Unpublished study received Apr. 27, 1977
under 100-541; prepared by Wildlife International, Ltd.,
submitted by Ciba-Geigy Corp., Greensboro, N.C.: CDL: 229607-
AN).
00080631 Johnston, C.D. (1965) Letter sent to Frank Lyman dated Mar 15, 1965
Summary of the 3-generation reproduction study of simazine in
the rat. (Unpublished study, including letter dated Mar 17,
1965 from C.D. Johnston to Joseph Marrus, received Mar 15, 1965
under 5F0447; prepared by Wbodard Research Corp., submitted by
Geigy Chemical Corp., New York, N.Y.; CDL:090488-F)
00080632 Ryskiewich, D.P. (1964) Metabolism of Simazine, Hydroxy-sunazine,
Atrazine and Hydroxy-atrazine by Rats. N.P. (Technical bul-
letin; also In unpublished submission received Mar 15, 1965
under 5F0447; submitted by Geigy Chemical Corp., New York, N.Y.;
CDL:090488-G)
00080633 Bowman, J.S. (1960) Metabolism Study. (Unpublished study, includ-
ing letters dated Apr 29, 1960 and Jul 26, 1960 from J.S. Bowman
to Joseph Marrus, received Mar 15, 1965 under 5F0447; prepared
by Hazleton Laboratories, Inc., submitted by Geigy Chemical
Corp., New York, N.Y.; CDL:090488-H)
00080635 Donoso, J.; Peterson, J.I. (1963) Hydroxyatrazine C14 and Hydrox-
ysimazine C14 Metabolism Studies in Rats. (Unpublished study
received Mar 15, 1965 under 5F0447; prepared by Wsodard Research
Corp., submitted by Geigy Chemical Corp., New York, N.Y.; CDL:
090488-J)
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- 6 -
GS-650070-1
GS-650070-2
GS-650070-3
GS-650070-4
GS-650070-5
GS-650070-6
GS-650070-7
GS-650070-8
GS-650070-9
GS-650070-10
GS-650070-11
GS-650070-12
GS-650070-13
GS-650070-14
GS-650070-15
Ciba-Geigy Corporation. (1976) Screen for Presence of
N-nitroso Compounds. Project No. 101904. [Unpublished
study submitted Dec. 2, 1976 and received Dec. 29, 1976.]
Ciba-Geigy Corporation. (1977) Report No. PQA-77: Analysis
of various Ciba-Geigy Triazine Technicals and Formulated
Products by HPIXVtEA including Method AG-315. [Submitted
May 9, 1977 and received May 10, 1977.]
EPA, Residue Chemistry Branch. (1982) [Memorandum from
William L. Anthony to Richard Mountfort concerning EPA
Reg. No. 19713-59 (Drexel Chemical Company, Registrant)
dated 8/26/82.]
EPA, Residue Chemistry Branch. (1983) [Memorandum from
William L. Anthony to Robert Taylor concerning EPA
Reg. No. 11603-11 (Agan Chemical Manufacturers, Ltd.,
Registrant) dated 6/1/83.]
EPA, Residue Chemistry Branch. (1983) [Memorandum frcm
William L. Anthony to Richard Mountfort concerning EPA
Reg. No. 100-541 (Ciba-Geigy Corporation, Registrant)
dated 6/23/83.]
Confidential Statement of Formula (EPA Reg. No. 100-541).
Confidential Statement of Formula (EPA Reg. No. 1812-262).
Confidential Statement of Formula (EPA Reg. No. 2749-292).
Confidential Statement of Formula (EPA Reg. No. 11603-11).
Confidential Statement of Formula (EPA Reg. No. 19713-59).
Confidential Statement of Formula (EPA Reg. No. 39511-5).
Cibes, H.R. (1959) Experimental Results with Radioactive
Simazine in Pineapple. [Unpublished study submitted by
Ciba-Geigy Corp. under PP#OF0855; RCB-116167.]
Dugger, J.M., Jr. (1959) The Metabolism of Simazine by
Sugarcane Plants, Second Report. [Unpublished study
submitted by Ciba-Geigy Corp. under PP#OF0855; RCB-
116167.]
Freed, V.H. (1967) The Absorption, Translocation and
Accumulation of Simazine in Strawberries, Preliminary
Report. [Unpublished study submitted by Ciba-Geigy
Corp. under PP#7F0534; RCB-114776.]
Hamilton, R.H. (1967) Tolerance of Several Grass Species
to 2-chloro-s-triazine Herbicides in Relation to
Degradation and Content of Benzoxazinone Derivatives.
J. Agric. Food Chem. Vol.?? [Submitted by Ciba-Geigy
Corp. under PP#7F0534; RCB-114776.]
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- 7 -
GS-650070-16
GS-650070-17
GS-650070-18
GS-650070-19
GS-650070-20
GS-650070-21
GS-650070-22
GS-650070-23
GS-650070-24
GS-650070-25
GS-650070-26
GS-650070-27
Leonard, O.A., and Lider, L.A. (1961) Toxicity and
Translocation of Herbicides supplied to Grape Rootings
through Solution Culture. Am. J. Enology and Viticulture
12:37-46. [Submitted by Ciba-Geigy Corp. under PP#7F0534?
RCB-114776.]
\
Shimabukuro, R.H. (1967) Atrazine Metabolism and Herbicidal
Selectivity. Plant Physiol. 42(9) : 1269-1276.
Submitted by Ciba-Geigy Corp. under PP#6F0620; RCB-115137.]
Ciba-Geigy Corp. (1960) Metabolism Study with Simazine-Ci4
in Rats Performed at the Hazleton Laboratories in Palo
Alto, California. [Report submitted April 29, 1960.
Submitted by Ciba-Geigy under PP#7F0525; RCB-114740.]
Ciba-Geigy Corp. (1963) Metabolism Study with Hydroxy-
atrazine-C^ and Hydroxysimazine-C^^ in Rats
performed at Wbodard Research. [Report submitted
October 11, 1963. Submitted by Ciba-Geigy Corp.
under PP#7F0525; RCB-114740.]
Ciba-Geigy Corp. (1964) Metabolism of Simazine, Hydroxy-
simazine, Atrazine, and Hydroxyatrazine by Rats. [Report
submitted April 3, 1964. Submitted by Ciba-Geigy Corp.
under PPf7F0525; RCB-114740.]
Ciba-Geigy Corp. (1970) Report No. GAAC-72096.
by Ciba-Geigy under PP#OF0996; RCB-166708.]
[Submitted
Ciba-Geigy Corporation. (1963) Method AG-14: Determination
of Simazine Residues. [Submitted by Ciba-Geigy under
PPf6Fl725; RGB.- None; See GS-650070-73.]
Ciba-Geigy Corporation (1963) kMethod AG-26: Extraction
of Animal Tissue prior to determining certain S-Triazine
Herbicides. [Submitted by Ciba-Geigy under PP#5F0447;
RCB-114441.]
Ciba-Geigy Corporation. (1965) Specific Application of
Analytical Bulletin No. 7 to the Analysis of Forage
Crops as required for Simazine PP*5F0447; [Submitted by
Ciba-Geigy under PP#5F0447; RCB-114441.]
Ciba-Geigy Corporation. (1966) Analytical Bulletin No. 7:
The Determination of Chlorotriazine Residues in Plant
Material, Animal Tissues and Water using the Ultraviolet
Method. [Submitted by Ciba-Geigy under PP#7FH534;
RCB-114776.]
Ciba-Geigy Corporation. (1966) The Determination of
Atrazine and Simazine in Milk by Gas Chromatography.
[Submitted by Ciba-Geigy under PP#5F0447; RCB-114441.]
Ciba-Geigy Corporation. (1969) Method AG-111: Determination
of Simazine Residues in Fish and Water by Microcoulometric
Gas Chromatography. [Submitted by Ciba-Geigy under
PP#OF0996; RCB-116708.]
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- 8 -
GS-650070-28
GS-650070-29
GS-650070-30
GS-650070-31
GS-650070-32
GS-650070-33
GS-650070-34
GS-650070-35
GS-650070-36
GS-650070-37
GS-650070-38
Ciba-Geigy Corporation. (1971) Analsytical Method REM
17/71R; Triazine Herbicides - Gas Chromatographic
Determination of Residues in Fruits, vegetables and
Plant Material. [Submitted by Ciba-Geigy under
PP*6E1725; RGB - None; See GS-650070-68.]
Ciba-Geigy Corporation. (1972) Method AG-232 A:
Determination of 2-chloro-4, 6-diamino-s-triazine
(G-28273) Residues in Sorghum by Gas Chromatography.
PP#OF0996; RCB-116708.]
Ciba-Geigy Corporation. (1973) Analytical Method REM
1/73; Parent Hydroxytriazines Residue Determination
in Plant Material by High-Performance Liquid Chromato-
graph. [Submitted by Ciba-Geigy under PP#6E1725;
RGB - None; See GS-650070-68.]
Ciba-Geigy Corporation. (1973) Method AG-213: Determination
of Residues of Simazine and its Monodealkylated
Metabolite, G-28279, in Fish by Gas Chromatography
Using Microcoulometric Detection. [Submitted hy Ciba-
Geigy under PP#OF0996; RCB-116708.]
Ciba-Geigy Corporation. (1973) Method AG-238: Residue
Determination of Simazine and its Metabolites, G-28279
and G-30414, in Pecans Using Gas Chrcmatography with
Microcoulometric Detection and Thin-Layer Chromatography.
[Submitted by Ciba-Geigy under PP#3F1378; RCB-118202.]
Ciba-Geigy Corporation. (1973) Report No. GAAC-73012:
Specificity of the Residue Determination of Simazine
in Pecans. [Submitted by Ciba-Geigy under PP#3F1378;
RCB-118202.]
Ciba-Geigy Corporation. (1973) Report No. GAAC-73026:
Validation of Analytical Method AG-232A for the
Determination of 2,4-diamino-6-chloro-s_-triazine.
[Submitted by Ciba-Geigy under PP#OF0996; RCB-116708.]
Ciba-Geigy Corporation. (1973) Report No. GAAC-73028:
Validation of Residue Method AG-111 and Storage Stability
of Simazine and G-28279 in Fish Tissue. [Submitted by
•Ciba-Geigy under PP#OF0996; RCB-116708.]
Ciba-Geigy Corporation. (1974) Method AG-261: Residue
Determination of Simazine and Its Chlorometabolites
G-28279 and G-28273 in Water. [Submitted by Ciba-
Geigy under PP#3G1394; RCB-118463.]
Gigger, R.P. (1966) Analysis for Simazine Residues.
[Submitted by Ciba-Geigy under PP#7F0534; RCB-114776.]
HEW, FDA. (1966) Method tryout of Analytical Bulletin
No. 7 for Bermuda and Johnsongrass. [Filed under
PP#5F0447; RCB-114441.]
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- 9 -
GS-650070-39
GS-650070-40
GS-650070-41
GS-650070-42
GS-650070-43
GS-650070-44
GS-650070-45
GS-650070-46
GS-650070-47
GS-650070-48
GS-650070-49
GS-650070-50
GS-650070-51
GS-650070-52
HEW, FDA. (1967) Method Tryout of Analytical Bulletin
for Corn and Oranges. [Filed under PP#7F0534; RCB-
114770.]
HEW, FDA. (1967) Method Trial for Simazine, Atrazine,
and Propazine in Milk. Dated Aug. 14, 1968. [Filed
under PP#7F0534; RCB-114770.]
Ciba-Geigy Corp. (1965) Determination of Simazine and
its Hydroxy Derivative in the Milk of Dairy Cows fed
Simazine in their Rations. [Submitted by Ciba-Geigy
Corp. under PPf5F0447; RCB-114441.]
Ciba-Geigy Corp. (1973) Report No. GAAC-73028.
[Submitted by Ciba-Geigy Corp. under PPtOF0996;
RCB-116708.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 390 and 631.
[Submitted by Ciba-Geigy Corp. under PP#7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1967) Test AG-A 265 and Table 6:
Field and Laboratory Experiments on the Use of
Simazine for Weed Control in Sub-Tropical Fruit and
Nut Orchards. [Submitted by- Ciba-Geigy Corp. under
PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test AG-A 635. [Submitted
by Ciba-Geigy Corp. under PP#7F0534. RCB-114776.]
Ciba-Geigy Corp. (1967) Tests AG-A 181> 341, 508,
802, 813, and 833. [Submitted by Ciba-Geigy Corp.
under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG 153, 225, and
319. [Submitted by Ciba-Geigy corp. under PP#F0534;
RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 326, 340, 509,
847, 1043, 1122, and 1123. [Submitted by Ciba-Geigy
Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test No. AG-A 371. [Submitted
by Ciba-Geigy Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 295, 304, and
900. [Submitted by Ciba-Geigy Corp. under PP#7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1967) Test No. AG-A 277. [Submitted
by Ciba-Geigy Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Simazine Residue Data:
Cranberries. [Submitted by Ciba-Geigy Corp. under
PP#7F0534; RCB-114776.]
-------
- 10 -
GS-650070-53
GS-650070-54
GS-650070-55
GS-650070-56
GS-650070-57
GS-650070-58
GS-650070-59
GS-650070-60
GS-650070-61
GS-650070-62
GS-650070-63
GS-650070-64
GS-650070-65
GS-650070-66
Ciba-Geigy Corp. (1967) Test AG-A 306 and Cornell
University Data dated July 1, 1964. [Submitted by
Ciba-Geigy Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test AG-A 730 and 1005.
[Submitted by Ciba-Geigy Corp. under PP#7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 216, 318, and
524; Simazine Residue Data: Grapes. [Submitted
by Ciba-Geigy Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test No. AG-A 277. [Submitted
by Ciba-Geigy corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 134, 138, 297,
298, 301, 305, 362, and 363. [Submitted by Ciba-Geigy
Corp. under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test AG-A 258, 378, 489, and
848. [Submitted by Ciba-Geigy under PP*7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1969) Test AG-A 1159. [Submitted
by Ciba-Geigy Corp. under PP#PF0792; RCB-115886.]
Ciba-Geigy Corp. (1967) Test AG-A 95. [Submitted by
Ciba-Geigy under PP#7F0534; RGB 114776.]
Ciba-Geigy Corp. (1973) Tests GAAC-73024 and AG-A 587,
1390, 1755, 2789, and 2824. [Submitted by Ciba-Geigy
under PP#7F1378; RCB-118202.]
Ciba-Geigy Corp. (1965) Tests AG-A 215, 273, and 380.
[Submitted by Ciba-Geigy Corp. under PP#7F0534;
PCB-114776.]
Ciba-Geigy Corp. (1965) Tests AG-A 119, 185, 342,
438, 548, 632, 876 and 888. [Submitted by Ciba-Geigy
under PP#5F0447; RCB-114441.]
Ciba-Geigy Corp. (1965) Tests AG-A 243, and 279.
[Submitted by Ciba-Geigy under PP#5F0447; RCB-114441.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 454 and 1289.
[Submitted by Ciba-Geigy under PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 217, 223, 285,
and 1294. [Submitted by Ciba-Geigy Corp. under
PP#7F0534; RCB-114776.]
-------
- 11 -
GS-650070-67
GS-650070-68
GS-650070-69
GS-650070-70
GS-650070-71
GS-650070-72
Ciba-Geigy Corp. (1967) Table 1-3, Supplement to:
Field and Laboratory Experiments on the Use of
Simazine for Weed Control in Sub-Tropical Fruit and
Nut Orchards. [Submitted by Ciba-Geigy Corp. under
PP#7F0534; RCB-114776.]
Ciba-Geigy Corp. (1967) Report No. GAAC-75069; RVA 46/75,
and 50/75; Test No. A3-A 903. [Submitted by Ciba-Geigy
Corp. under PP#6E1725; RGB - None - See below:]
Under PPS6E1725 (All Ciba-Geigy)
Matson, H.M. (1975) Report No. GAAC-75069.
Results of Tests on the Amount of Residue remaining
in Bananas including a Description of Analytical
Method used.
Schenker, M. (1973-74) RVA 46/75, Simazine and
Anetryn. Residues in Bananas, Honduras.
Schenker, M. (1974) RVA 48/75 Simazine and Anetryn.
Residues in Bananas, Costa Rica.
Schenker, M. (1974) RVA 50/75 Simazine and Anetryn.
Residues in Bananas, Costa Rica.
Turchick, J.T. (1964) Test No. AG-A-903, Analytical
Residues Report - Simazine in Bananas, United Fruit
Co., New York, NY.
Ciba-Geigy Corp. (1967) Table Nos. 4 and 8: Field and
Laboratory Experiments on the Use of Simazine for Weed
Control in Sub-Tropical Fruit and Nut Orchards.
[Submitted by Ciba-Geigy Corp. under PP#7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1967) Test Nos. AG-A 91, 94, 233,
and 240. [Submitted by Ciba-Geigy Corp. under PP#7F0534;
RCB-114776.]
Ciba-Geigy Corp. (1970) Test No. AG-A 1713. [Submitted
by Ciba-Geigy Corp. under FAP#1H2572; RCB-070328.1
Ciba-Geigy Corp. (1970) Report No. GAAC-74054: Test
Nos. AG-A 3259 I and II; Report No. GAAC-73048:
Test Nos. AG-A 2940, 2905, and 2899; Report No.
GAAC-70013: Test No. AG-A 1555. [Submitted by Ciba-
Geigy Corp. under PPfOF0996; RCB-116708.]
-------
- 12 -
GS-650070-73
GS-650070-74
GS-650070-75
GS-650070-76
GS-650070-77
GS-650070-78
GS-650070-79
GS-650070-80
GS-650070-81
GS-650070-82
GS-650070-83
Ciba-Geigy Corp. (1970) Report No. GMC-70013: Tes
Nos. 512, 659, 725, 777, 782, 783, 817, 832, 860,
861, 918, 920, 950, 986, 988, 989, 1065, 1089 and
1142. [Submitted by Ciba-Geigy Corp. under PP#OF0996
[Samples were analyzed for intact simazine residue
only; the tolerance is expressed in terms of the
combined residues of simazine plus its metabolites
G-28273 and G-28279.
Mattson, A.M. and Solga, J. (1963) Residues in Body
Tissues of Sheep and Cattle Receiving Simazine in
Their Diet as compared with Residues of Propazine
and Atrazine in Animals Similarly Treated. [Unpublished
study submitted by Ciba-Geigy corp. under PP#5F0447;
RCB-114441.]
Mattson, A.M. and Solga, J. (1965) Determination of
Simazine and Its Hydroxy Derivative in The Milk of
Dairy Cows fed Simazine in Their Rations. [Unpublished
study submitted by Ciba-Geigy Corp. under PP#5F0447;
RCB-114441.]
Wbodard Research Corporation. (1961) Determination of
Simazine in Milk Following Dietary Feeding to Dairy
Cattle. [Unpublished study submitted by Ciba-Geigy
Corp. under PP#5F0447; RCB-114441.]
Dugger, J.M. and Humphreys, T.E. (1959) The Metabolism
of Simazine by Sugarcane Plants, Preliminary Report
I. [Unpublished study submitted by Ciba-Geigy Corp.
under PP#OF0855; RCB-116167.]
Humphreys, T.E. (1961) The Metabolism of Atrazine and
Simazine by Sugarcane Plants Four to Seven Months of
Age, Final Report. [Unpublished study submitted by
Ciba-Geigy Corp. under PP#OF0855; RCAB-116167.]
Bakke, J.E. and Robbins, J. (1968)
and Simazine by The Goat and Sheep.
Metabolism of Atrazine
[ACS Abstr. 155A43.]
Foster, T.S. and Khan, S.U.
Atrazine by The Chicken.
24(3):566-570.]
(1976) Metabolism of
[J. Agric. Food Chem.
Pillai, P., Weete, J.D., Diner, A.M. and Davis, D.E.
(1979) Atrazine Metabolism in Box Crabs. [J. Environ.
Qual. 8(3):277-280.]
Robbins, J.D., Bakke, J.E. and Feil, V.J. (1968)
Metabolism of 2-chloro-4,6-bis (isopropylamino)-s-
triazine (Propazine-14c) in The Milk of Goat and Sheep.
[J. Agric. Food Chem. 16(4):698-700.]
Ciba-Geigy Corp. (1976) Acute Oral Data. [Submitted by
Ciba-Geigy Corp.] [Prepared by IBT Laboratory for Ciba-
Geigy Corp., Tox. Doc. 001892, EPA Reg. No. 100-437.]
-------
- 13 -
GS-650070-84 Ciba Geigy Corp. (1972) Acute and Subacute Toxicity
Feeding Studies of Simazine with Young Adult Bobwhite
Quail, GSRI Project No. NC459. [Unpublished Study
received Apr. 22, 1977; submitted by Ciba-Geigy,
Greensboro, N.C.; Ace. No. 229607.]
GS-650070-85 Sanders, H.O. (1970) Toxicities of sane Herbicides to
Six Species of Freshwater Crustaceans. [Journal of
the Water Pollution Control Federation 42(8):1544-1550.]
-------
'APPENDIX II-2 I
OMB Approval No. 20004468 (Expires 12-31-83)
EPA REGISTRATION NO.
FIFRA SECTION 3(C)(2)(B) SUMMARY SHEET
PRODUCT NAME
APPLICANTS NAME
DATE GUIDANCE DOCUMENT ISSUED
With respect to the requirement to submit "generic" data imposed by the FIFRA section 3(C)(2)(B) notice contained in the referenced
Guidance Document, I am responding in the following manner
D1. I will submit data in a timely manner to satisfy the following requirements. If the test procedures I will use deviate from (or are not
specified in) the Registration Guidelines or the Protocols contained in the Reports of Expert Groups to the Chemicals Group, OECD
Chemicals Testing Programme, I enclose the protocols that I will use:
O 2. I have entered into in agreement with one or more other registrants under FIFRA section 3(C)(2)(B)(ii) to satisfy the following data
requirements. The tests, and any required protocols, will be submitted to EPA by:
NAME OF OTHER REGISTRANT
D 3. I enclose a completed "Certification of Attempt to Enter Into an Agreement with Other Registrants for Development of Data" with
respect to the following data requirements:
D 4. I request that you amend my registration by deleting the following uses (this option is not available to applicants for new products):
D 5. I request voluntary cancellation of the registration of this product (This option is not available to applicant! for new products.)
REGISTRANTS AUTHORIZED REPRESENTATIVE
SIGNATURE
DATE
EPA Form 8580-1 (10-82)
-------
APPENDIX H-3
OMB Approval No. 2000W68 (Expires: 12-31-93)
(To qualify, certify A Ll^ four items)
CERTIFICATION OF ATTEMPT TO ENTER
INTO AN AGREEMENT WITH OTHER REGISTRANTS
FOR DEVELOPMENT OF DATA
1. I am duly authorized to represent the following firm(s) who are subject to the require-
ments of a Notice under FIFRA Section 3(c)(2)(B) contained in a Guidance Document
to submit data concerning the active ingredient:
GUIDANCE DOCUMENT DATE
ACTIVE INGREDIENT
NAME OP FIRM
EPA COMPANY NUMBER
(This firm or group of firms is referred to below as "my firm".)
2. My firm is willing to develop and submit the data as required by that Notice, if necessary- However, my firm would prefer to enter
into an agreement with one or more other registrants to develop jointly, or to share in the cost of developing, the following required
items or data:
3. My firm has offered in writing to enter into such an agreement Copies of the offers are attached. That offer was irrevocable and included an offer to be
bound by an arbitration decision under FIFRA Section 3(c)(2)(B)(iii) if final agreement on ail terms could not be reached otherwise. This offer was made
to the following firm(s) on the following data(s):
NAME OF FIRM
DATE OF OFFER
However, none of those firm(s) accepted my offer.
4. My firm requests that EPA not suspend the registration(s) of my firm's product(s), if any of the firms named in paragraph (3) above
have agreed to submit the data listed in paragraph (2) above in accordance with the Notice. I understand EPA will promptly inform
me whether my firm must submit data to avoid suspension of its registration(s) under FIFRA Section 3(c)(2)(B). (This statement
does not apply to applicants for new products.) I give EPA permission to disclose this statement upon request.
TYPED NAME
SIGNATURE
DATE
EPA Form 86804 (10-82)
-------
Appendix III-l
PTOEDCT SPECIFIC DMA REPORT
EPA Begistraticn No.
_Guidanoe Document for_
Date
Registration
Guideline No.
5158.20
PFDQJCT
CHEfflSTK?
61-1
61-2
61-3
62-1
62-2
62-3
63-2
63-3
63-4
63-5
63-6
63-7
63-8
63-9
63-10
63-11
63-12
63-13
63-14
63-15
63-16
63-17
63-18
63-19
63-20
63-21
S 158. 135
TOXICOLOGY
81-1
81-2
81-3
81-4
81-5
81-6
Name of Teat
Identity of
ingredients
Statement of
composition
Discussion o£
formation of
ingredients
Preliminary
analysis
Certification of
limits
Analytical methods
for enforcement
limits
Color
Physical state
Odor
Melting point
Boiling point
Density, bulX-
density, or
specific gravity
Solubility
Vapor pressure
Dissociation
constant
Octanol/Vater
partition
coefficient
PH
Stability
Oxidizing/reducing
reaction
Flanmability
ExDlodability
Storage stability
Viscosity
M^ibilitv
Corrosion
characteristics
Dielectric break-
down voltage
Acute oral LD-50,
rat
Acute dermal
LD-50
Acute inhalation,
LC-50 rat
Primary eye
irritation, rabbit
Primary dermal
irritation
Dermal sensitiza-
ticn
Test not
required
for my
product
listed
above
(check
below)
I am complying with
data requirements by
Citing MRtDt
Submit-
ting
Data
(At-
tached)
(For EJ>A Use Only)
Accession Numbers
Assigned
-------
APPENDIX IV-2
LABELING REQUIREMENTS OF TOE FIFRA, AS AMENDED (REFER TO THE SAMPLE LABELS FOLLOWING)
ITEM
1
2
3
4
5
6A
6B
7
7A
7B
LABEL ELEMENT
Product name
Company name
and address
Net contents
EPA Est. No.
EPA Reg. No.
Ingredients
statement
Pounds/ga 1 Ion
statement
Front panel
precaut ionary
statements
Keep Out of Reach
of Children
(Child hazard
warning )
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
All products
All products
Liquid products
where dosage
given as Ibs.
ai/unit area
All products
All products
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
None
None
None
None
Front panel
Front panel
Front panel
Front panel
Front panel
PREFERRED
Center front
panel
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel,
immediately
before or
following
Reg. No.
Immediately
following
product name
Directly below
the main
ingredients
statement
Above signal
word
Immediately
below child
hazard
warning
COMMENTS
If registrant is not the producer, must
be qualified by "Packed for . . .,"
"Distributed by. • •»" etc.
May be in metric units in addition to
U.S. units
Must be in similar type size and run
parallel to other type.
May appear on the container instead of
the label.
Text must run parallel with other text
on the panel.
All front panel precautionary statements
must be grouped together, preferably
blocked .
Note type size requirements.
Note type size requirements.
-------
APPENDIX IV-2 (continued)
ITEM
7C
7D
7E
8
8A
8B
LABEL ELEMENT
Skull & cross-
bones and word
POISON (in red)
Statement of
practical
treatment
Referral
statement
Side/back panel
precau t ionary
statements
Hazards to
humans and
domestic
animals
Environmental
hazards
APPLICABILITY
OF REQUIREMENT
All products
which are Cat-
egory I based
on oral, der-
mal, or inhala-
tion toxic ity
All products
in Categories
I, II, and III
All products
where pre-
cautionary
labeling
appears on
other than
front panel.
All products
All products
in Categories
I, II, and III
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
Category^ I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped with
side panel
precautionary
statements.
Front panel
None
None
None
PREFERRED
Both in close
proximity to
signal word
Front panel
for all.
''
Top or side
of back panel
preceding
directions
for use
Same as above
Same as above
COMMENTS
\
"^-
Must be grouped under the headings in
8A, 8B, and 8C; preferably blocked.
Must be preceded by appropriate signal '"*
word.
Environmental hazards include bee
caution where applicable.
-------
APPENDIX IV-2 (continued)
ITEM
8C
9A
9C
10A
IOC
10D
U.S.
LABEL ELEMENT
Physical or
chemical
hazards
Restricted
block
Misuse
statement
Re-entry
statement
Storage and
disposal block
Directions
for use
APPLICABILITY
OF REQUIREMENT
All pressurized
products, others
with flash
points under
150°F
All restricted
products
All products
All
cholinesterase
inhibitors
All products
All products
PLACEMENT ON LABEL
REQUIRED
None
Top center
of front
panel
Immediately
following
statement of
classifica-
tion or
ahead of
directions
for use
In the
directions
for use
In the
directions
for use
None
PREFERRED
Same as above
Preferably
blocked
i
Immediately
after misuse
statement
Immediately
before
specific
directions
for use or
at the end of
directions
for use
None
COMMENTS
Includes a statement of the terms of
restriction. The words "RESTRICTED USE
PESTICIDE" must be same type size as
signal word.
Must be set apart and clearly distin-
guishable from from other directions
for use.
May be in metric as well as U.S. units
-------
RESTRICTED USE PESTICIDE
PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS
(4 DOMESTIC ANIMALS
DANGER
ENVIRONMENTAL HAZARDS/
PHYSICAL OR CHEMICAL
HAZARDS &/!}
DIRECTIONS FOR USE
it a a wofetion ol Federal law to use
mis oroouct m a manner inconsistent
wild its Boeing
RE-ENTRY STATEMENT
(It Applicable)
CATEGORY OF APPLICATOR
STORAGE AND
DISPOSAL
STORAGE —
DISPOSAL =
CROP:
RESTRICTED USE
PESTICIDE
FOR RETAL SALE TO AND APPLICATION ONLY BY
CERTIFIED APPLICATORS OR PERSONS UNDER THEIR
DIRECT SUPERVISION
PRODUCT
NAME
ACTIVE MGREOIENT:
INERT INGREDIENTS:
TOTAL:
100.00%
THIS PRODUCT CONTAINS IBS OF PER GALLON
KEEP OUT OF REACH OF CHILDREN
is) DANGER — POISON
STATEMENT OF PRACTICAL TREATMENT
IF SWALLOWED =
IF INHALED =
IF ON SKIN =
IF IN EYES =
SEE SIDE PANEL FOR ADOrTIONAL PRECAUTIONARY STATEMENTS
MFG8Y =
TOWN, STATE ==
ESTABLISHMENT NO.
EPA REGISTRATION NO.
NET CONTENTSr
CROP:
CROP:
CROP:
CROP:
CROP:
WARRANTY STATEMENT
-------
Appendix IV-3
PHYSICAL-CHEMICAL HAZARDS
Criteria
I. Pressurized Containers
A. Flashpoint at or below
20 °F; or if there is a
flashback at any valve
opening.
B. Flashpoint .above 20°F
and not over 80'F; or
if the flame extension
is more than 18 inches
long at a distance of
6 inches from the
valve opening.
C. ALL OTHER PRESSURIZED
CONTAINERS
II. Non-Pressurized Containers
A. Flashpoint at or below
20°F.
B. Flashpoint above 20°F
and over 80°F.
C. Flashpoint over 80 *F
and not over 150°F.
D. Flashpoint above
150°F.
Required Label Statement
Extremely flammable.
Contents under pressure.
Keep away from fire, sparks,
and heated surfaces. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame. Do
not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Contents under pressure.
Do not use or store near
heat or open flame. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Extremely flammable. Keep
away from fire, sparks, and
heated surfaces.
Flammable. Keep away from
heat and open flame.
Do•not use or store near
heat and open flame.
None required.
-------
Appendix IV-5
STORAGE AND DISPOSAL INSTRUCTIONS FOR PESTICIDES
All products are required to bear specific label instructions
about storage and disposal. Storage and disposal instructions
must be grouped together in the directions for use portion of
the label under the heading STORAGE AND DISPOSAL. Products
intended solely for domestic use need not include the heading
"STORAGE AND DISPOSAL." The STORAGE AND DISPOSAL heading
must appear in the minimum type size listed below:
I \ Required type size
I Size of label I for the heading
I front panel in I STORAGE AND DISPOSAL
I square inches I (all capitals)
I
110 and under 6 point
I Above 10 to 15 8 point
I Above 15 to 30 10 point
I Over 30 12 point
Storage and disposal instructions must be set apart and
clearly distinguishable from other directions for use.
Blocking storage and disposal statements with a solid line is
suggested as a means of increasing their prominence.
A. Storage Instructions;
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed.
Each registrant must develop his own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, heat, sunlight,
friction, or contaminating substances or media.
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
while opening or closing container.
-------
Appendix IV-5
(continued)
4. Instructions on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been
spilled, and precautions to minimize exposure if damage occurs
5. General precautions concerning locked storage, storage in
original container only, and separation of pesticides
during storage to prevent cross-contamination of other
pesticides, fertilizer, food, and feed.
6. General storage instructions for household products should
emphasize storage in original container and placement in
locked storage areas.
B. Pesticide Disposal Instructions;
The label of all products, except those intended solely for
domestic use, must bear explicit instructions about pesticide
disposal. The statements listed below contain the exact wording
that must appear on the label of these products:
1. The labels of all products, except domestic use, must
contain the statement, "Do not contaminate water, food,
or feed by storage or disposal."
2. Except those products intended solely for domestic use,
the labels of all products that contain active ingredients
appearing on the "Acutely Hazardous" Commercial Pesticide
Products List (RCRA "E" List) at the end of this appendix
or are assigned to Toxicity Category I on the basis of
oral or dermal toxicity, skin or eye irritation potential,
or Toxicity Category I or II on the basis of acute inhala-
tion toxicity must bear the following pesticide disposal
statement:
"Pesticide wastes are acutely hazardous. Improper dis-
posal of excess pesticide, spray mixture, or rinsate is
a violation of Federal Law. If these wastes cannot be
disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control
Agency, or the Hazardous Waste representative at the
nearest EPA Regional Office for guidance."
The labels of all products, except those intended for
domestic use, containing active or inert ingredients
that appear on the "Toxic" Commercial Pesticide Products
List (RCRA "F" List) at the end of this appendix or
presently meet any of the criteria in Subpart C, 40 CFR
261 for a hazardous waste must bear the following pesticide
disposal statement:
-------
\ Appendix IV-5
(continued)
"Pesticide wastes are toxic. Improper disposal of excess
pesticide, spray mixture, or rinsate is a violation of
Federal Law. If these wastes cannot be disposed of by
use according to label instructions, contact your State
Pesticide or Environmental Control Agency, or the Hazardous
Waste representative at the nearest EPA Regional Office
for guidance."
Labels for all other products, except those intended for
domestic use, must bear the following pesticide disposal
statement:
"Wastes resulting from the use of this product may be
disposed of on site or at an approved waste disposal
facility."
3. Products intended for domestic use only must bear the
following disposal statement: "Securely wrap original
container in several layers of newspaper and discard in
trash."
C. Container Disposal Instructions
The label of each product must bear container disposal
instructions appropriate to the type of container.
1. All products intended for domestic use must bear one
of the following container disposal statements:
Container Type
Statement
Non-aerosol products 1 Do not reuse container (bottle, can, jar). I
I(bottles, cans, jars)I Rinse thoroughly before discarding in trash.I
I Non-aerosol products
I(bags)
Do not reuse bag. Discard bag in trash
Aerosol products
IReplace cap and discard containers in
I trash. Do not incinerate or puncture.
2. The labels for all other products must bear container disposal
instructions, based on container type, listed below:
Container Type
Statement
Metal
containers
(non-aerosol)
Triple rinse (or equivalent).Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
authorities.
Plastic containers
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay out of smoke.
Glass containers
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
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Appendix IV-5
(continued)
Container Type
Statement
Fiber drums
with liners
.
Paper and
plastic bags
Compressed gas
cylinders
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities .
If drum is contaminated and cannot be
reused*, dispose of in the same manner.
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Return empty cylinder for reuse (or
similar wording).
^Manufacturer may replace this phrase with one indicating whether
and how fiber drum may be reused.
2. The labels for all other products must bear container
disposal instructions, based on container type, listed
on the first page of this Appendix.
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Appendix IV-5
(continued)
Pesticides that are hazardous wastes under 40 CFR 261.33(e) and (f)
when discarded.
"Acutely Hazardous" Commercial Pesticides (RCRA "E" List)
Active Ingredients, (no inerts);
Acrolein
Aldicarb
Aldrin
Ally! alcohol
Aluminum phosphide
4-Aminopyridine
Arsenic acid
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroaniline
Cyanides (soluble cyanide salts, not specified elsewere)
Cyanogen chloride
2-Cyclohexyl-4,6-dinitrophenol
Dieldrin
0,0-Diethyl S-[2-ethylthio)ethyl] phosphorodithioate
(disulfoton, Di-Syston)
0,0-Diethyl 0-pyrazinyl phosphorothioate (Zinophos)
Dimethoate
0,0-Dimethyl 0-p-nitrophenyl phosphorothioate (methyl parathion)
4,6-Dinitro-o-cresol and salts
4,6-Dinitro-o-cyclohexylphenol
2,4 Dinitrophenol
Oinoseb
Endosulfan
Endothall
Endrin
Famphur
Fluoroacetamide
Heptachlor
Hexanethyl tetraphosphate
Hydrocyanic acid
Hydrogen cyanide
Methorny1
alpha-Naphthylthiourea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide (OMPA, schradan)
Parathion
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Appendix IV-5
(continued)
"Acutely Hazardous" Commercial Pesticides (RCRA "E" List)
Active Ingredients continued;
Pheny liner curie acetate (PMA)
Phorate
Potassium cyanide
Propargyl alcohol
Sodium azide
Sodium cyanide
Sodium fluoroacetate
Strychnine and salts
0,0,0,0-Tetraethyl dithiopyrophosphate (sulfotepp)
Tetraethyl pyrophosphate
Thallium sulfate
Thiofanox
Toxaphene
Warfarin
Zinc phosphide
There are currently no inert ingredients for commercial pesticides
on the "Acutely Hazardous" List (RCRA "E" List).
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Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA "F" List)
Active Ingredients;
Acetone
Acrylonitrile
Amitrole
Benzene
Bis(2-ethylhexyl)pthalate
Cacodylic acid
Carbon tetrachloride
Chloral (hydrate)
Chlordane (technical)
Chlorobenzene
4-Chloro-m-cresol
Chloroform
o-Chlorophenol
4-Chloro-o-toluidine hydrochloride
Creosote
Cresylic acid
Cyclohexane
Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[c,d]-pentalen-2-one
(kepone, chlordecone)
1,2-Dibromo-3-chloropropane (DBCP)
Dibutyl phthalate
S-3,3-(Dichloroallyl diisopropylthiocarbamate (diallate, Avadex)
o-Dichlorobenzene
p-Dichlorobenzene
Dichlorodifluoromethane (Freon 12*)
3,5-Dichloro-N-(1,l-dimethyl-2-propynyl) benzamide (pronamide/Kerb)
Dichloro diphenyl dichloroethane (ODD)
Dichloro diphenyl trichloroethane (DDT)
Dichlorethyl ether
2,4-Dichlorophenoxyacetic, esters and salts (2,4-D)
1,2-Dichloropropane
1,3-Dichloropropane (Telone)
Dimethyl phthalate
Ethyl acetate
Ethyl 4,4'-dichlorobenzilate (chlorobenzilate)
Ethylene dibromide (EDB)
Ethylene dichloride
Ethylene oxide
Formaldehyde
Furfural
Hexachlorobenzene
Hexachlorocyclopentadiene
Hexachloroethane
Hydrofluoric acid
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Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA "F" List)
Active Ingredients;
Isobutyl alcohol
Lead acetate
Lindane
Maleic hydrazide
Mercury
Methyl alcohol
Methyl bromide
Methyl chloride
2,2'-Methylenebis (3,4,6-trichlorophenol) (hexachlorophene)
Methylene chloride
Methyl ethyl ketone
4-Methyl-2-pentanone (methyl isobutyl ketone)
Naphthalene
Nitrobenzene
p-Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentaclorophenol
Phenol
Phosphorodithioic acid, 0,0-diethyl, methyl ester
Propylene dichloride
Pyridine
Resorcinol
Safrole
Selenium disulfide
Silvex
1,2,4,5-Tetrachlorobenzene
1,1,2,2-Tetrachloroethane
Tetrachlorpethylene
2,3,4,6-Tetrachlorophenol
Thiram
Toluene
1,1,1-Trichloroethane
Trichloroethylene
Trichloromonofluoromethane (Freon 11*)
2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
2,4,5-Trichlorophenoxyacetic acid (2,4,5-T)
Xylene
-------
Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA
Inert Ingredients ;
F" List)
Acetone
Acetonitrile
Ac etophenone
Acrylic acid
Aniline
Benzene
Chlorobenzene
Chloroform
Cyclohexane
Cyclohexanone
Dichlorodifluoromethane (Freon 12®)
Diethyl phthalate
Dimethylamine
Dimethyl phthalate
1,4-Dioxane
Ethylene oxide
Formaldehyde
Formic acid
Isobutyl alcohol
Meleic anhydride
Methyl alcohol (methanol)
Methyl ethyl ketone
Methyl methacrylate
Naphthalene
Saccharin and salts
Thiourea
Toluene
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Trichlorofluoromethane (Freon 11®)
Vinyl chloride
Xylene
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1 ATTACHMENT A
PRODUCTS AFFECTED BY THIS
REREGISTRATION PROCESS (SIMAZINE)
Following is a list of'your products affected by this rereg-
istration process. If this list is incomplete or inaccurate
in any way, please notify the Product Manager (PM) identified
in the letter.
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ATTACHMENT B
REGISTRANTS WITH PESTICIDE PRODUCTS CONTAINING
THE ACTIVE INGREDIENT SIMAZINE
The information attached will allow registrants with pesticide
products containing the above ingredient to contact one
another regarding joint data development or sharing the cost
of data development under section 3(c)(2)(B) of FIFRA. This
information includes the following: EPA Reg. No., company
name, company address, active ingredient, percentage of active
ingredient and type of formulation, such as Manufacturing-Use
Product (MP), Technical Product (TP), Wettable Powder (WP),
and Emulsifiable Concentrate (EC).
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