GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
TRICHLORFON
AS THE ACTIVE INGREDIENT
(057901)
CAS 52-68-6
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D.C. 20460
JUNE 30, 1984
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TABLE OF CONTENTS
Introduction 1-3
I. Regulatory Position 4-78
II. Requirement for Submission of Generic Data 79-Hi6
III. Requirement for Submission of Product-Specific
Data 117-120
IV. Submission of Revised Labeling and Packaging
Information 1 "21-12 6
A. Label Contents
1. Product Name
2. Company Name and Address
3. Net Contents
4. Product Registration Number
5. Producing Establishment
Registration Number
6A Ingredient Statement
6B Pounds Per Gallon Statement
7. Front Panel Precautionary Statements .
7A Child Hazard Warning Statements. . . .
7B Signal Word
7C Skull and Crossbones and Word Poison .
7D Statement of Practical Treatment . . .
7E Referral Statement
8. Side/Back Panel Precautionary Labeling
8A Hazard to Humans and Domestic Animals.
8B Environmental Hazard
8C Physical or Chemical Hazard
9 Misuse Statement
IDA Storage and Disposal Block
10B Directions for Use
B. Collateral Information .
V. Instructions for Submission.
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APPENDICES
Bibliography II-l
FIFRA S3(c)(2)(B) Summary Sheet -
EPA Form 8580-1 II-2
Certification of Attempt to Enter Into an
Agreement With Other Registrants for Development
of Data EPA Form 8580-6 II-3
i
Product Specific Data Report (End-Use Products).... II.I.rJL.
Sample Label Formats IV-1
Table of Labeling Requirements IV-2
Physical/Chemical Hazards Labeling Statement IV-3
Storage and Disposal Instructions IV-5
Note: Appendices IV-4 and IV-6 are not germane to this
document and are not included.
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INTRODUCTION
The Federal Insecticide, Fungicide, and Rodenticide Act
(FIFRA Section 3(g), as amended in 1978, directs EPA to
reregister all pesticides as expeditiously as possible. Each
registrant of a manufacturing use product of the active
ingredient who wishes to continue to sell or distribute that
product must apply for reregistration.
To fulfill this Congressional mandate, we have established
the Registration Standards program which will review all pesti-
cide active ingredients first registered before January 1,
1977. These pesticides will be reviewed in use clusters
which are prioritized on the basis of a ranking scheme giving
preference to pesticides used on food and feed crops.
The Registration Standards program involves a thorough
review of the scientific data base underlying pesticide
registrations and an identification of essential but missing
studies which may not have been required when the product
was initially registered or studies that are now considered
insufficient. Our reassessment results in the development
of a regulatory position, contained in this document, on
each pesticide and its uses. The regulatory position may
require the registrant to modify product labels to provide
additional precautionary statements, restrict the use of the
pesticide to certified applicators, provide reentry intervals,
modify uses or formulation types, specify certain packaging
limitations, or other requirements to assure that proper use
of the pesticide poses no potential adverse effects to human
health or the environment.
The scientific review, which is not contained herein
but is available upon request, concentrates on the technical
grade of the active ingredient and identifies missing generic
data. However, during the review of these data we are also
looking for potential hazards that may be associated with
the formulated (end-use) products that contain the active
ingredient. If we find serious concerns, we will bring
formulated products under the provisions of the Registration
Standards program to the extent necessary to protect the
public.
EPA has the authority under FIFRA $3(c)(2)(B) to require
that certain registrants submit generic data that will answer
our questions regarding the hazard that may result from the
intended use of the pesticide under review. Further, S3(c)
(2)(B) provides that these data are to be submitted by
those registrants who do not qualify for the formulator's
exemption [FIFRA S3(c)(/)(D)]. Normally, this means that
the registrants who are responsible for filling the data
gaps are the manufacturing-use product producers (basic
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suppliers of the active ingredient). However, end-use producers
will not qualify for the formulator's exemption if the source
of their active ingredient: (1) is not registered with EPA,
and/or (2) is produced by the registrant's firm, or a firm
which has ownership in common with the registrant's firm.
These end-use producers can qualify for the formulator's
exemption if they change their source of supply to a registered
source, provided the source does not share ownership in
common with the registrant's firm. If the end-use product
registrant decides to switch sources, a new Confidential
Statement of Formula, EPA Form 8570-4, must be submitted to
the appropriate Product Manager within 90 days of receipt of
this Guidance Document. The chart on the following page
shows what is generally required of those who do and do not
qualify for the formulator's exemption in the Registration
Standards program.
If you decide to request the Agency to discontinue the
registration of any of your products subject to the reregistra-
tion requirements of this Guidance Document, please notify
the Product Manager named in the cover letter, within 90
days from the receipt of this document, that you wish to
voluntarily cancel the registration(s). If you decide to
maintain your product registration(s), you must provide the
information described in the following pages within the time-
frames outlined. EPA will issue a notice of intent to cancel
or suspend the registration of any currently registered
product if you fail to comply with the requirements set
forth in this Guidance Document.
This Guidance Document will be supplemented by EPA with
additional information about compliance with data support
requirements. In Monsanto v. Administrator, EPA was recently
enjoined from implementing in any way the "mandatory data
licensing" aspects of S3(c)(l)(D) of FIFRA. EPA is assessing
the implications of the injunction for the reregistration
process. Because this situation is currently unresolved, EPA
has decided to proceed with the requirements in this Guidance
Document which do not relate to compliance with the $3(c)(l)(D)
provisions and to supplement the Document with additional
guidance when circumstances permit. Failure to comply with
the provisions of the subsequent guidance will also result
in issuance by EPA of an intent to cancel the affected product
registration(s).
Registrants are reminded that $6(a)(2) of FIFRA requires
you at any time to submit factual information raising concerns
of possible unreasonable adverse effects of a pesticide. You
should notify the Agency of interim results of studies in
progress if those results show possible unreasonable adverse
effects.
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PRODUCTS SUBJECT TO THE
REGISTRATION STANDARDS PROGRAM
ACTION(S) REQUIRED TO
MAINTAIN REGISTRATION
I. Products That Do Not Qualify
For The Formulator's Exemption
A. Single Active Ingredient
Products*
These products must be reregis-
tered. To obtain reregistration,
labeling, packaging and data
requirements must be satisfied
in accordance with the Regis-
tration Standards Guidance
Document.
B. Multiple Active Ingredient
Products
These products will not be
reregistered at this time.
However, generic data required
to continue the registration of
the active ingredient under
review, as described in the
Registration Standards Guidance
Document, will be required and
some labeling precautions may
also be required.
II. Products That Do Qualify For
The Formulator's Exemption
Only when additional restric-
tions or labeling are needed to
protect man or the environment
will these products be subject
to the Registration Standard
requirements. Affected products
will be dealt with in a variety
of ways, including but not
limited to the Label Improvement
Program and special intent
to cancel notices.
*End-use products of registrants who also produce a manufacturing-
use product will not be required to be reregistered provided that
registrant fulfills the requirements specified in the Guidance
Document for manufacturing-use product(s). Such end-use products
will be subject to the labeling changes required for products in "II"
above. If there are no manufacturing-use products registered by any
company end-use products will be required to be reregistered.
NOTE: If all registrants in "I" above fail to meet the requirements in
I-A and B above, then the registrants in 'II" lose their right to
qualify for the formulator's exemption and 'Become subject to the
requirements in I-A and B.
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II. REGULATORY POSITION AND RATIONALE
A. INTRODUCTION
This Guidance Document describes the Agency's regulatory posi-
tion on registered manufacturing-use products (MPs) containing
the insecticide trichlorfon. This position is based on a con-
sideration of all accepted uses of pesticide products containing
trichlorfon as the sole active ingredient, under Sections 3 and
24(c) of the FIFRA. Other considerations include the known
chemical, environmental, and the toxicological characteristics
of this pesticide and the established tolerances for residues
in or on food and feed commodities. From these considerations
the Agency sets forth the data and labeling requirements that
must be met by registrants and applicants of trichlorfon pro-
ducts in order for a product to be registered or reregistered
under this Document. Only those registration and labeling
requirements for current and future substantially similar MPs
are addressed here. Future MPs that differ appreciably from
those described in this Document may require that amendments
be made to this Document to reflect the differences.
B. Chemical Description and Use Profile
Trichlorfon is a common name for the insecticide dimethyl-
(2,2,2-trichloro-l-hydroxyethyl)phosphonate as determined by
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the International Organization For Standardization (ISO). The
Chemical Abstracts Registry (CAS) number is 52-68-6, and the
EPA Chemical Reference number is 057901. Trichlorfon registered
in the U.S. is manufactured by Mobay Chemical Corp., Intrachem
S.A., Aceto Chemical Co., Inc., and Makhteshim Beer-Sheva
Chemical Works Ltd.
Technical trichlorfon is a white crystalline solid with a melt-
ing point of 81-82°C. The empirical formula is C/jHgO^^P and
the molecular weight is 257.6. The boiling point for technical
trichlorfon is 100°C at 0.1 mm Hg and the vapor pressure is
7.8 mm Hg at 20°C. Trichlorfon is soluble in water (9* at
20°C), alcohols, methylene chloride and ketones and slightly
soluble in aromatic solvents.
There are thirteen federally registered manufacturing-use pro-
ducts (MPs) containing trichlorfon as a single active ingre-
dient and one MP containing trichlorfon in combination with
other active ingredients. A total of 118 end-use products
containing trichlorfon are registered under Section 3 of FIFPA
and seventeen are registered under Section 24(c) of FIFRA (Spe-
cial Local Needs Registration).
Trichlorfon is a selective insecticide registered for use on a
variety of vegetable, fruit, and field crops; livestock;
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ornamental and forestry plantings; in agricultural premises
and domestic dwellings; and for the control of parasites on
fish in designated aquatic environments. Trichlorfon is an
organophosphate pesticide exhibiting both contact and stomach
poison action. Trichlorfon is commercially available as
emulsifiable concentrate, soluble concentrate (liquid, solid),
pressurized liquid, ready to use liquid, pelleted/tableted,
impregnated material, dust, granular, and wettable powder/dust,
Most products are applied by using either ground or aerial
equipment. The particular type of equipment is determined
by site and equipment available. Trichlorfon is classified
as a general use pesticide.
C. Regulatory Position
Based on a review and evaluation of data and other relevant
information on trichlorfon, the Agency has made the following
determinations:
1. The data that have been reviewed do not show that the
criteria listed in 40 CFR S162.11(a) have been met or
exceeded for the uses of trichlorfon listed in this
Guidance Document. However, because of gaps in the data
base, the Agency cannot complete a full assessment of
trichlorfon.
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2. The Agency is unable to complete a tolerance reassess-
ment because of extensive residue chemistry and toxicology
data gaps. Future requests for tolerances will not he con-
sidered or approved until all the chronic toxicology data
requirements have been satisfied.
3. No federal or state reentry intervals have been established
for trichlorfon. However, based on available environmental
fate and toxicology data, the Agency is requiring an interim
reentry interval of 24 hours. This reentry interval will be
re-evaluated when the data requirements in Tables A and B
have been satisfied.
4. Manufacturing-use pesticide products containing trichlorfon
as the sole active pesticide ingredient may be registered
for sale, distribution, reformulation, and use, subject to
the terms and conditions specified in this Guidance Document,
5. Registrants must provide or agree to develop additional
data, as specified in the data tables, in order to maintain
existing registrations or to obtain new registrations for
substantially similar MPs.
6. There are unique label precautions that must be included on
the labeling for trichlorfon products. These precautions
are cited in Section G of this Document.
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D. REGULATORY RATIONALE
JThe Agency has determined that it should continue to allow
the registration of trichlorfon7after considering the following:
1. Dichlorvos RPAR
Dichlorvos (DDVP), a putative metabolite of trichlorfon, was
originally referred and accepted for the Rebuttable Presumption
Against Registration (RPAR) process because scientific studies
indicated that dichlorvos was mutagenic as well as potentially •
carcinogenenic, neurotoxic and teratogenic in laboratory animals
The RPAR Decision Document on Dichlorvos was issued by the
Agency on September 30, 1982. In this document (i.e., Decision
Document on Dichlorvos, Office of Pesticides and Toxic
Substances, U.S. EPA, Washington, D.C., September 30, 19R2)
the Agency evaluated the available data on dichlorvos in
accordance with 40 CFR 162.11 (Criteria for Determination of
Unreasonable Adverse Effects) and concluded that the existing
evidence did not support the issuance of an RPAR for dichlorvos
and consequently, that an RPAR for trichlorfon as a precursor
of dichlorvos was also not warranted.
The DDVP Decision Document concluded that additional data on
carcinogenicity and mutagenicity were needed to complete the
risk assessment for dichlorvos. DDVP was removed from the
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RPAR process and returned to the registration process. On
March 23, 1983, the Agency issued a Data Call-in Notice
under FIFRA Section 3(c)(2)(b), reguesting data on potential
mutagenic effects of dichlorvos be submitted by March 23,
1985. However, the Agency will wait until the continuing
National Cancer Institute (NCI) dichlorvos bioassay on
carcinogenicity is completed (currently scheduled for com-
pletion in 1985) and evaluated prior to determining if
additional data on the carcinogenicity of dichlorvos will
be reguired. Since dichlorvos can be metabolized from
trichlorfon, evaluation of these studies will be necessary
for the completion of the trichlorfon risk assessment.
2. Trichlorfon RPAR
Trichlorfon was originally referred and entered the
Rebuttable Presumption Against Registration (RPAR) process*
because scientific studies suggested that trichlorfon may be
oncogenic, teratogenic, fetotoxic and mutagenic. In this
document the Agency has evaluated the available data on
trichlorfon in accordance with 40 CFR 162.11 (Criteria for
Determination of Unreasonable Adverse Effects) and concluded
that the existing evidence does not support the issuance of
an RPAR for trichlorfon, because the existing data base is
inadeguate for a valid risk assessment. Additional data are
required to complete the risk assessment for trichlorfon.
*Federal Register, Vol. 43, No. 77, Thurs. April 20, 1978.
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Oncogenicity, chronic feeding, teratogenicity, mutagenicity,
inhalation, dermal, neurotoxicity, and metabolism studies
are required as specified in Table A. A decision as to
whether trichlorfon should reenter the RPAR process will he
made when these studies are completed.
3. Acute Toxicity
Adequate data indicate that trichlorfon is in Toxicity Category
II on the basis of acute oral effects and Category III on
the basis of dermal effects. Human hazard precautionary
statements associated with these Toxicity Categories [40 CFR
162.10 (h)(2)(i)] should minimize the acute hazards associated
with these routes of exposure. Adequate studies are unavailable
to fully assess the acute inhalation, primary eye, primary dermal
sensitization effects of trichlorfon to humans. The Agency
has no valid acute inhalation, primary eye, dermal, or dermal
sensitization data for trichlorfon manufacturing-use products.
4. Subchronic and Oncogenicity and Chronic Feeding
The Agency has no acceptable subchronic studies, chronic
feeding or Oncogenicity studies. The available data suggest
that trichlorfon induces tumors at high dietary levels
(500 and 1000 ppm), but are insufficient as the basis for
an oncogenic risk assessment because of major protocol
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design and/or reporting deficiencies, as follows:
(i) High mortality in all groups (control and experi-
mental), resulting in shortened duration of studies;
(ii) inadequate dosage regimens;
(iii) too few tissues (selected only at terminal sacrifice)
in 5 or less animals per sex group examined;
(iv) inadequate histopathological data.
Additional subchronic, oncogenicity and chronic feeding studies
are required as specified in Table A.
5. Mutagenicity
There is sufficient evidence that trichlorfon or its degrada-
tion products is mutagenic to bacteria and mammalian cells
in vitro, and thus these data requirements are satisfied.
Trichlorfon may also be clastogenic (cause chromosome break-
age), as suggested by inadequately-controlled and/or incon-
clusive studies in vivo. Inconsistent results have been
reported with many systems, however, and the instability of
trichlorfon may be an important consideration in interpreting
these data. Therefore, additional data on chromosome aberrations
are required.
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6. Teratogenicity
Trichlorfon administered by gavage to pregnant animals during the
critical period of major organogenesis appears to be fetotoxic
and teratogenic in rabbits, rats, mice and hamsters, but only at
doses greater than those causing significant maternal effects
and/or death. However, a teratology study in the rat where
trichlorfon was fed during gestation did report an increased
rate of anomalies at a dietary dose below the dose producing
maternal effects. This study was not considered acceptable
according to current Agency guidelines since the authors did
not present the teratology data on a litter basis nor indicate
the number of fetuses with specific malformations. Further,
an insufficient number of pregnant females were available for
analysis. Therefore the Agency is requiring an adequate
dietary teratology study in the rat to resolve this issue.
7. Tolerance Assessment and Exposure
The ADI has been based on a NOEL for cholinesterase inhibition
from a one-year feeding study in dogs. However, this study
has now been judged inadequate according to current Agency
guidelines since there were only 2 animals per sex per feeding
level; individual animal data were not fully reported; and
gross histopathologic examinations were incomplete or inade-
quate, and only a limited number of tissues were sampled.
Further, hyperplastic adrenal nodules were found at all dose
levels tested including the dose from which the ADI was
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based. Because of the above listed deficiencies in the
design and conduct of the study, the Agency lacks confidence
in interpreting the results. The significance of the nodules
will be determined by a required additional dog study. The
present study does not support the ADI regardless of the
reported results. A complete tolerance reassessment is
necessary with a new data base, including chronic feeding
studies, being required.
Based on residue chemistry and toxicology considerations,
however, there is no adequate data to confirm that current
tolerances are likely to expose the public to unreasonable
adverse effects.
8. Incidents
The Pesticide Incident Monitoring System (PIMS) reports covering
the period from 1966 to January 1980 include 52 incidents
involving the pesticide trichlorfon. Of these, 22 involved
trichlorfon alone, while the remaining 30 involved trichlorfon
and other pesticides. The human and domestic animal adverse
effects reported in these incidents appear to have been the
result of improper handling, lack of protective clothing or
ingestion of trichlorfon.
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9. Ecological Effects
Based on studies available to assess hazards to wildlife
and aquatic organisms, technical trichlorfon is characterized
as highly to moderately toxic to both cold water and warm water
fish, very highly toxic to freshwater invertebrates and highly
toxic to birds. Label precautions required by this Guidance
Document should reduce the hazard to wildlife and aquatic
organisms.
10. Environmental Fate
Available data are insufficient to fully assess the environ-
mental fate of trichlorofon. Trichlorfon degrades rapidly
in aerobic soils under nonsterile conditions, but in sterile
soils trichlorfon is stable. Trichlorfon also degrades
rapidly in alkaline pond water but remains stable in pond water
under acidic conditions. The major degradate in both soil
and pond water is DDVP. Trichlorfon is very mobile in soils
of varying textures and organic contents. The potential for
ground water contamination by the parent compound may be
mediated by its degradation in soil, however, the potential
for ground water contamination by DDVP cannot be assessed
due to data gaps. Forestry and aquatic field dissipation
studies did not show a potential for trichlorfon to persist
in leaves, leaf-litter, soil, water, or sediment, nor did
they show a potential for trichlorfon to accumulate in
nontarget fish.
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11. Summary of Regulatory Rationale
Under FIFRA the Agency cannot cancel or withhold registra-
tion simply because data are missing or inadeguate (see
Sections 3(c)(2)(B) and 3(c)(7) of the FIFRA). Rather,
issuance of this Guidance Document provides a mechanism for
identifying data needs. These data will be reviewed and
evaluated when they are received and the Agency will determine
at that time whether they will affect the registrations of
trichlorfon.
E. CRITERIA FOR PRODUCTS SUBJECT TO THE GUIDANCE DOCUMENT
This Guidance Document covers products that contain trichlorfon
as the sole active ingredient and the chart in the Introduction
describes the extent to which such products are subject to
this Guidance Document. Applicants for registration or
reregistration of such products must comply with all the terms
and conditions described herein. This includes making a
commitment to fill data gaps on a schedule specified by the
Agency. Also,, applicants for reregistration must follow the
instructions contained in this Guidance Document and complete
and submit the appropriate forms within the specified times.
End-use products must be in compliance with the label changes
specified in this Document.
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F. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Statements
To be covered under this Guidance Document, manufacturing-use
products must contain trichlorfon as the sole active ingredient.
Each MP formulation proposed for registration or reregistration
must be fully described with an appropriate certification of
limits.
2. Acute Toxicity Limits
The Agency will consider for registration any MP whose acute
toxicity category (I, II, III, IV) is supported by adequate
acute toxicology data and appropriate precautionary statements
in the labeling.
G. REQUIRED LABELING
All manufacturing-use products containing trichlorfon must
bear appropriate labeling as specified in 40 CFR 162.10.
1. Label Requirements for Manufacturing-Use Products
a. Ingredient Statement
The ingredient statement for MPs must list the active ingredient
as:
(dimethyl-(2,2,2-trichloro-l-hydroxyethyl)
phosphonate % .
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b. Use Pattern Statement
All MPs must state that they are intended only for formulation
into end-use products (EPs) for any of the use patterns listed
below. A limiting factor will be the data that support each
use pattern. No use may be included on the label where the
registrant fails to agree to comply with the data requirements
in either Table A or Table B for that use pattern.
0 Terrestrial, non-domestic, food crop uses on:
Alfalfa (seed crop), clover (seed crop), alfalfa
(including grass mixtures), artichoke (globe),
banana, barley, beans (dried-type, succulent), beans-
lima, blueberries, beets, Brussels sprouts, cabbage,
carrot, cauliflower, citrus fruits, clover (including
grass mixtures), collards, corn (field, pop, sweet),
cotton, flax, lettuce, oats, pasture grass, peanuts,
peas (field: blackeyed, cowpeas, crowder, southern),
peppers, pumpkin, rangeland grasses, safflower,
soybeans (seed crop), sugar beets, tomato, wheat;
also: field crops, truck crops (field borders).
0 Terrestrial, non-domestic, non-food uses on:
tobacco, ornamental evergreens (including pine),
shade trees, woody shrubs and vines, herbaceous
plants (including annuals, aster, chrysanthemum,
daisy, iris, and nursery stock), lawns, turf,
recreational areas (including picnic areas).
0 Aquatic, non-food uses on: bait fish, gold fish.
0 Domestic outdoor uses on: ornamental lawns,
domestic dwellings (outdoor).
0 Forestry uses: forest trees.
0 Greenhouse, food uses on: cucumbers, peppers,
spinach, beets (root crop), beans (lima, green and
wax), corn (sweet and field), peas. These uses
are from a 24 (c) label restricting applic?.tions to
research crops.
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0 Greenhouse, non-food use on:
Weed hosts of plant pathogens. This use is from a
24(c) label.
0 Indoor uses:
Dairy cattle (non-lactating), beef cattle, horses,
dairy barns (including manure and garbage dump
treatment), milking rooms including manure and
garbage dump treatment, animal buildings and
premises (including barns, shelters, stables,
feedlots, holding pens, manure and garbage dump
treatment), animal hospitals, cat quarters, dog
quarters (including kennels), dogs, domestic
dwellings, garbage dumps, latrines, recreational
areas (including picnic areas), poultry packing
plants, red meat packing plants, commercial,
institutional, and industrial areas (inedible
product areas), eating establishments (inedible
product areas), food processing, handling and
storage plants/areas (inedible product areas).
The attached "EPA Index to Registered Pesticides" entry summarizes
all currently acceptable uses for single active ingredient
products containing trichlorfon, including sites of application,
target pests, dosage rates, restrictions and limitations, and
the method and frequency of application.
c. Precautionary Statements
Labels for all MP products containing trichlorfon must bear
statements reflecting the hazards to man and the environment
[40 CFR 162.10]. Trichlorfon is in Toxicity Category II on
the basis of acute oral effects and Category III on the basis
of acute dermal effects. The Agency has no valid acute inhala-
tion, primary eye, primary dermal, or dermal sensitization data
for trichlorfon MP products.
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0 Based on data reviewed by the Agency, the environ-
mental hazard statement below is required to
appear on all MPs containing trichlorfon:
"This pesticide is toxic to fish and wildlife
and is extremely toxic to aquatic invertebrates.
Do not discharge effluent containing this product
into lakes, streams, ponds, estuaries, oceans, or
public waters unless this product is specifically
identified and addressed in an NPDES permit. Do
not discharge effluent containig this product to
sewer systems without previously notifying the
sewage treatment plant authority. For guidance
contact your State Water Board or Regional Office
of the EPA."
2. Label Requirements for End-Use Products
a. Ingredient Statement
The ingredient statement for EPs must list the active
ingredient as:
dimethyl-[2,2,2-trichloro-1-hydroxyethyl]
phosphonate % .
b. Precautionary Statements
Labels for all EPs containing trichlorfon must bear a
statement reflecting the hazard to man and the environment
[40 CFR 162.10] .
0 Based on data reviewed by the Agency, the following
environmental hazards statements are required to
appear on the EPs:
All trichlorfon products intended for outdoor use
must bear the following statement:
"This pesticide is toxic to fish and wildlife
and is extremely toxic to aquatic invertebrates."
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Additional precautionary statements are required
as indicated below:
Trichlorfon products intended for direct applications
to ponds:
"Consult your State Fish and Game Agency
before applying this product to public
waters. Permits may be required before
treating such waters."
Trichlorfon products intended for use in forestry;
"Do not apply directly to water or wetlands
not under forest canopy. Runoff and drift
from treated areas may be hazardous to aquatic
organisms in neighboring areas."
Trichlorfon products intended for outdoor uses other
than direct applications to ponds or forestry;
"Do not apply to water or wetlands. Run-
off from treated areas may be hazardous to
aquatic organisms in neighboring areas."
The Agency is currently considering various approaches
to address the endangered species concerns for this
and other chemicals. This standard may be amended
to incorporate the results of this additional review.
0 To avoid the possible misuse of trichlorfon in eating
establishments the following statement is required
for all EPs used in eating establishments.
"This product shall not be used in rooms or areas
where food is either consumed or prepared."
Bee precautionary language per PR Notice 68-19 is no
longer required since the data indicates that
trichlorfon has a low toxicity to bees.
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0 The reentry statement below must appear on all
trichlorfon labels with directions for use on crops:
"Do not reenter treated fields within 24 hours
unless protective clothing is worn."
Refer to PR Notice 83-2 for additional information
on reentry and worker protection labeling require-
ments .
H. TOLERANCE REASSESSMENT
The previously established tolerances for combined residues
of trichlorfon and its cholinesterase-inhibiting metabolites
are published in 40 CFR 561.190 and 40 CFR 180.198. A summary
of these tolerances is presented in Table 1.
The data for trichlorfon residues in or on the following raw
agricultural commodities are adequate to fill the residue data
requirements:
beets, blueberries; peanut hulls and vine hay; birdsfoot
trefoil hay (including chaff); corn grain; fresh corn;
corn forage and fodder, forage of barley, oats, and
wheat; bananas; peanuts; and the fat, meat, and meat
by-products of goats, horses, and sheep.
Sufficient residue data are not available to assess the
adequacy of the trichlorfon tolerances for the following
commodities (and their processed products, if applicable):
carrots, sugar beets and tops, lettuce, Brussels sprouts,
cabbage, cauliflower, collards, cowpeas, dried beans,
lima beans, snap beans, bean vines, cowpea vines, lima
bean vines and hay, peppers, tomatoes, pumpkins, citrus
fruits and dried citrus pulp, barley grain and straw,
21
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pat grain and straw, wheat grain and straw, pasture and
rangeland grass forage and hay, alfalfa forage and hay,
clover forage and hay, artichokes, cottonseed, flax
seed and straw, safflower seed, cattle (fat, meat, and
meat by-products), and milk.
Residue data are required for processed products of the
following commodities to determine the necessity of food/feed
additive tolerances:
citrus fruits; cottonseed; wheat grain; sugar beets;
and tomatoes.
Residue data for tobacco are required to determine the human
hazard associated with this trichlorfon use.
Poultry residue studies are required to determine the necessity
of trichlorfon tolerances for poultry fat, meat, and meat
byproducts; a tolerance for eggs is not required.
No group crop tolerances are appropriate at the present time.
I
Residue data and tolerance proposals must be submitted for
the following raw agricultural commodities for which tolerances
are not currently established, but intrastate registrations
exist:
strawberries; watermelon; broccoli; kale; spinach;
garlic; onions; radishes; rutabagas; celery; and turnips.
No new crop groupings can be established at this time because
of extensive residue chemistry data gaps. Compatibility
between Codex MRLs and U.S. tolerances will be assessed when
22
-------
data gaps specified in Table A have been submitted and
evaluated.
The lack of adequate animal and plant metabolism studies
precludes a determination of the trichlorfon residues of
concern in plants and animals. Before the submission of
additional residue data, it is imperative that the residues
of concern be determined. The registrant is to conduct
adequate plant and animal metabolism studies prior to
generating residue data so that all the components of the
residue (parent compound and metabolites) can be identified,
The previously established ADI for trichlorfon is 0.1250
mg/kg/day and the TMPC, based on the established tolerances
for residues of trichlorfon as cited under 40 CFR 180.198,
is 0.0627 mg/day assuming a 1.5 kg diet; the TMPC currently
accounts for only 0.84% of the ADI. No adequate study
currently supports the previously established ADI. A new
ADI will be established when the chronic toxicity data re-
quirements specified in Table A are satisfied.
23
-------
TABLE I.
SUMMARY OF PRESENT TOLERANCES a/
Tolerances (ppn)
Commodity United States
Alfalfa
Alfalfa, hay
Artichokes
Apples
Bananas
Barley, forage
Barley, grain
Barley, straw
Beans, dried
Beans, lima
Beans, lima vine hay
Beans, lima vines
Beans, blackeyed
Beans , snap
Beans, vines
Beets
Beets, sugar
Beets, sugar tops
Birdsfoot trefoil, hay
Blueberries
Brussels sprouts
Cabbage
Carrots
Cattle fat
Cattle, mbypf/
Cattle, meat
Cattle, offal
Cauliflower
Celery
Cereal grains
Citrus fruit
Citrus (dry pulp)
Cherries
Chili peppers
Chickpeas
Clover
Clover hay
Col lards
Corn, fodder
Corn, forage
Corn, fresh
Corn, grain
Cottonseed
Cowpeas
Cowpeas, vines
60.0
90.0
0.1 (N)V
-
2.o
-------
TABLE I.
SUMMARY OF PRESENT TOLERANCES a/(continued)
Tolerances (ppm)
Commodity
Flax, straw
Flaxseed
Goats, fat
Goats, mbyp
Goats, meat
Grapes
Grass, pasture
Grass, pasture hay
Grass, range
Grass, range, hay
Horses, fat
Horses, mbyp
Horses meat
Kale
Lettuce
Linseed
Milk
Mustard green
Oats, forage
Oats, grain
Oats, straw
Peaches
Peanuts
Peanuts, vine hay
Peanuts, vine hulls
Peppers
Pigs, carcass meat
Pigs, edible offal
Pigs, fat
Pumpkins
Radish
Rapeseed
Rutabagas
Safflower seed
Salisfy
Sheep, fat
Sheep, mbyp
Sheep, meat
Soya, beans
Squash
Spinach
Sugar beets
United
1.
0.
0.
0.
0.
-
60.
90.
240.
240.
0.
0.
0.
0.
0.
-
0.
-
50.
0.
1.
-
0.
4.
4.
0.
-
-
-
0.
-
-
States
0
1
1
1
1
0
0
0
0
1
1
1
1
1
01
0
1
0
05
0
0
1
1
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
(N)
Canada Mexico International Codex <
_ ^ .
-
-
-
-
- - 0
- -
- . -
- -
- -
-
-
-
0.1 (N) - 0
0.1 (N) 0.1 (N) 0
- - 0
- - 0
- - 0
- -
- -
-
0
0.05 0
- -
4.0
0.1 (N) - 1
- - 0
- - 0
- - 0
- - 0
- - 0
0.1 (N) - 0
—
-
-
-
-
.5
-
-
-
-
-
-
-
.2
.5
.1
.05
.1
-
-
-
.2
.1
-
-
.0
.1
.1
.1
.1
.1
.1
0.1 (N)
0.1
0.1
0.1
(N)
(N)
(N)
0.1 (N)
0.1 (N)
0.1
0.1 (N)
0.1
0.1 (N)
0.1 (N)
0.1
0.5
0.05
25
-------
TABLE I.
SUMMARY OF PRESENT TOLERANCES a/ (continued)
Tolerances (ppm)
Commodity
Stawberries
Tomatoes
Turnips
Wheat, forage
Wheat, grain
Wheat, straw
United States
_^
0.1 (N)
-
50.0
0.1 (N)
1.0
Canada Mexico International Codexg/
^ ^
0.1 (N) 0.1 (N)
0.1 (N)
50.0
0.1 (N)
1.0
1.0
0.2
0.1
-
-
. —
a/ Tolerance is based on residues of trichlorfon and its cholinesterase-
inhibiting metabolites.
b/ (N) is neglibible residues
£/ NMT 0.2 ppm will be present after peel is removed.
d/ Reflecting 0.1 ppm (N) in or on shelled beans.
e/ MBYP = Meat byproducts
f/ Including sweet K + CWHR.
£/ International Codex "tolerances" are expressed as MRLs or maximum residue
limits.
26
-------
Index of Currently Acceptable Uses**
EPA Index to Pesticide Chemicals
C057901 DIMETHYL (2,2,2-TRICHLORC~l-HYDROXYETHYL)PHOSPHONATE*
TYPE PESTICIDE; Insecticide
FORMULATIONS;
Tech (90%, 97%, 98%)
FI (80%, 82%)
D (3%, 5%, 8%)
G (0.4%, 0.92%, 1%, 3%, 3.5%, 4%, 5%, 6.2%)
P/T (5%, 37.8%, 90%)
WP/D (37.8%)
Impr (1%)
SC/L (4 Ib/gal, 6 Ib/gal, 40.5%)
SC/S (50%, 80%)
RTU (1.5 Ib/gal, 8%)
GENERAL WARNINGS AND LIMITATIONS; Trichlorfon does not significantly af-
fect beneficial insects (parasites, predators, and pollinators) especially
when applied at the minimum recommended rates per acre. Trichlorphon is
not specifically recommended for the control of aphids, cabbage loopers,
or mites, but some suppression of these pests may result from listed dos-
ages. To avoid plugging, use 50 mesh screens in sprayers when applying
soluble concentrate/solid formulations. Do not use in conjunction with
alkaline materials such as lime or lime sulfur, or with summer oils or
dormant oils.
Definition of Terms;
**Computed from tablespoon/teaspoon dosage.
***Exact computation of actual dosage is not possible because of the lack
of weight/volume information on the label. Extrapolation from other for-
mulations reveals that the dosage from this label appears to fall within
the range shown by formulations with known weight/volume ratios.
Claims for pest control limited to suppression of population are indicated
by parenthesized pest name.
*trichlorfon
Dipterex
Dylox
Neguvon
trichlorphon
**covers single active ingredient labeling only
Issued: 3-22-82 III-057901-1
Provisional Update: 6-14-84
27
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-mCHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site And Pest
AGRICULTURAL CROPS
Dosages and Tolerance, Use, Limitations
Formulation(s)
General Warnings and Limitations; Do not apply to or allow to drift onto
varieties of sorghum which are sensitive to phosphates as burning of sor-
ghum or milo may occur. Injury to foliage and fruit of apples has been
reported. For soluble concentrate/liquid formulations, apply per acre
rates in a minimum of 1 gallon of water per acre by aircraft or ground
equipment or apply undiluted by aircraft or ultra low volume ground equip-
ment. For soluble concentrate/solid formulations, apply in sufficient
water for thorough coverage by aircraft or ground equipment.
/23001AA
/28069AA
Alfalfa
Alfalfa-Grass Mixture
ITBJADA
Alfalfa caterpillar 0.375-0.5
Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
60 ppm (fresh)
90 ppm (hay)
No pregrazlng or preharvest Interval
through 1 pound per acre of dilute
spray formulations for foliar appli-
cation. Do not make more than 3 ap-
plications per cutting.
3 day pregrazlng or preharvest in-
terval through 1 pound per acre of
ultra low volume spray formulations
for foliar application. Do not make
more than 1 application per cutting.
7 day pregrazing or preharvest in-
terval through 1 pound per acre of
dust formulations for foliar appli-
cation. Do not make more than 1 ap-
plication per cutting.
14 day pregrazing or preharvest in-
terval through 1 pound per acre of
bait formulations for broadcast soil
application. Do not make more than
1 application per cutting.
Use patterns for spray formulations
include alfalfa in mixed stands with
grasses.
Foliar application. May be applied
by aircraft. Some 4 pounds per gal-
lon soluble concentrate/liquid for-
mulations may be applied undiluted
as an ultra low volume spray by air-
craft or ground equipment.
Issued: 3-22-82
III-057901-2
28
-------
ITBMBUA
IQAMABA
ITBCCFA
IQAMARA
IQAQAAA
ITBCCNA
IRAFAAA
ITBCCBA
ITBCCRA
/23001AA
ITBJADA
ITBMBUA
ITBCCNA
IQAMARA
IQAQAAA
ITBCCBA
ITBCCRA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use, Limitations
Formulation(s)
Alfalfa cluster (continued)
Alfalfa webworm
Alfalfa plant bug
Armyworm
Lygus bugs (includ-
ing tarnished
plant bug)
Stink bugs
Beet armyworm
Leaf hoppers
Variegated cutworm
Western yellow-
striped armyworm
0.25-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
(Alfalfa)
Alfalfa caterpillar 0.9-1 Ib/A
Alfalfa webworm
Beet armyworm
Lygus bugs (includ-
ing tarnished
plant bug)
Stink bugs
Variegated cutworm
Western yellow-
striped armyworm
(3-8% D)
Foliar application.
by aircraft.
May be applied
1 Ib/A
(5% D)
(3-5% G)
Armyworm
Beet armyworm
Crickets (including [Bait]
mole crickets)
Cutworms (climbing
and surface feed-
ing including
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Issued: 3-22-82
III-057901-3
29
-------
ITABACA
ITBCCRA
ITBCCFA
/23001BA
/23003BA
ITBCCFA
IQAMARA
IQAQAAA
ITBCCBA
/13018AA
ITBLABA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HyDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Alfalfa cluster (continued)
Pest list continued from previous page.
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped army worm
Armyworm
Alfalfa (seed crop)
Clover (seed crop)
1 Ib/A
(5% P/T)
[Bait]
Broadcast soil application. Make 1
application per cutting.
Armyworm
Lygus bugs
Stink bugs
Variegated cutworm (40.5%
SC/L)***
(50-80% SC/S)
Alfalfa-Grass Mixture See Alfalfa cluster.
90 ppm (hay)
7 day prehervest interval through
1.5 pounds per acre for foliar ap-
plication.
Do not cut green crop for feed or
forage. Chaff may be used for feed
or forage.
1-1.5 Ib/A Foliar application to seed crop.
(4-6 Ib/gal May be applied by aircraft.
SC/L)
Artichoke (Globe)
Artichoke plume
moth
2-2.5 Ib/A
(5-8% D)
0.1 ppm
14 day preharvest interval through
2.5 pounds per acre for foliar ap-
plication.
Foliar application. May be applied
by aircraft.
Issued: 3-22-82
III-057901-4
30
-------
EPA Index to Pesticide Chemicals
/06002AA
I1AJACA
/28063AA
/28009AA
/28062AA
/28065AA
ITBCCFA
IVAHAAA
ITABACA
ITBCABA
ITBCCFA
ITBCCNA
ITBMBWA
ITBCCBA
ITBCBVA
ITBWAFA
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use, Limitations
Formulation(s)
Banana 2 ppm
0.2 ppm (in pulp after peel is re-
moved)
No preharvest interval through 0.5
pound per acre for foliar applica-
tion.
Banana caterpillar 0.4-0.5 Ib/A Foliar application. Repeat at 14
(80% SC/S) day intervals as needed.
0.1 ppm (grain and flazseed)
1 ppm (straw)
50 ppm (barley, oats and wheat
forage)
21 day preharvest interval through 1
pound per acre for foliar applica-
tion or soil application (broad-
cast). For spray formulations, do
not make more than 3 applications
during the growing season. Applica-
tions may be made without removal of
livestock.
For bait formulations, do not graze
treated fields. Do not feed treated
straw to dairy or meat animals.
Armyworm
Crickets
Saltmarsh cater-
pillar
Cutworms (climbing
and surface
feeding)
Armyworm
Beet armyworm
Beet webworm
Variegated cutworm
Bertha armyworm
Diamondback moth
1 Ib/A
(5% D)
(4-5% G)
[Bait]
0.5-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
III-057901-5
31
-------
/15001AA
/15003AA
/15025AA
ITBCCFA
IOAAAEA
IQAMARA
INAPAFA
IQAQAAA
ITBCCBA
ITBCBTA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCBAA
INBUAAA
ITABACA
ITBCCRA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXyETHYL)PHOSPHONATE
Site and Pest
Beans, Dried-Type
Beans, Succulent
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
0.1 ppm (beans, dried and snap)
1 ppm (vines)
14 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast).
Do not feed treated vines to dairy
or meat animals.
Armywonn 1-1.5 Ib/A
Dipterous leaf- (3-8% D)
miners (4-6 Ib/gal
Lygus bugs SC/L)
Mexican bean beetle (40.5%
Stink bugs SC/L)***
Variegated cutworm
Western bean cut-
worm
Armyworm 1.5 Ib/A
Beet armyworm (5% D)
Crickets (including (3.5-5% G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Darkling beetles
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Foliar application.
by aircraft.
May be applied
(50-80% SC/S)
1-1.5 Ib/A
(3-8% D)
or
0.5-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing*
Issued: 3-22-82
III-057901-6
32
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
/15025AA
/15025CA
/15003CA
/14001CA
/28005CA
/15005CA
/10010CA
/2801bCA
/28017CA
/13024CA
Site and Pest
Beans, Lima
Dosages and Tolerance, Use, Limitations
Formulation(s)
12 ppm (beans [reflecting 0.1 ppm
in or on the shelled beans], bean
vines, bean vine hay)
14 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication.
30 day preharvest interval through
1.5 pounds per acre of bait formula-
tions for soil application (band or
broadcast).
Do not make more than 2 applications
during the growing season.
Refer to Beans, Dried-Type cluster.
Beans, Lima
(greenhouse research
Beans, Succulent
(greenhouse research
Beets (root crop)
(greenhouse research
Corn, Field
(greenhouse research
Corn, Sweet
(greenhouse research
Cucumbers
(greenhouse research
Peas
(greenhouse research
Peppers
(greenhouse research
Spinach
(greenhouse research
N.F.
crops)
crops)
crops)
crops)
crops)
crops)
crops)
crops)
crops)
This use only occurs on Special
Local Need (24(C)) labeling and has
not been included in this entry.
Refer to appropriate labeling for
use information and limitations.
Beans, Succulent
See Beans, Dried-Type cluster.
Issued: 3-22-82
III-057901-7
33
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONAIE
/14001AA
ITBMBUA
ITBCCNA
ITBMBWA
IOAAAEA
IQAMARA
ITABACA
ITBCCBA
ITBMBUA
ITBMBWA
IOAAAEA
ITABACA
ITBCCNA
IQAMARA
ITBCCBA
Site and Pest
Beets
Alfalfa webworm
Beet armyworm
Beet webworm
Dipterous leaf-
miners
Lygus bugs
Saltmarsh cater-
pillar
Variegated cutworm
Alfalfa webworm
Beet webworm
Dipterous leaf-
miner
Saltmarsh cater-
pillar
Beet armyworm
Lygus bugs
Variegated cutworm
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
0.1 ppm
28 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast).
Do not harvest tops for food.
1-1.5 Ib/A
(3-8% D)
Foliar application.
by aircraft.
May be applied
1 Ib/A
6 Ib/gal
SC/L)
(50-SOZ SC/S)
1-1.5 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
0.5-1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
Issued: 3-22-82
III-057901-8
34
-------
ITBCCFA
IVAHAAA
•ITABACA
ITBCCXA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Beets (continued)
Armyworm 1.5 Ib/A Soil application (band). Apply over
Crickets (5% D) the row and around base of plants.
Saltmarsh cater- (3-5% G)
pillar [Bait] Broadcast soil application. May be
Surface feeding applied by aircraft. For fields
cutworms with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Beets (root crop)
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
/23011BA
Birdsfoot trefoil (seed crop)
/01009AA
Blueberry
/13006AA
/13007AA
/13008AA
ITBWAFA
ITBJAHA
ITBCCBA
I1BCCRA
Brussels Sprouts
Cabbage
Cauliflower
Diamondback moth
Imported cabbage-
worm
Variegated cutworm
Western yellow-
striped armyworm
1 Ib/A
(3-8% D)
90 ppm (hay)
This use only occurs on Special
Local Need (24(C)) labeling and has
not been included in this entry.
Refer to appropriate labeling for
use information and limitations.
0.1 IN) ppm
This is a new use established sub-
sequent to the development of this
entry. Refer to appropriate label-
ing for use information and limita-
tions.
0.1 ppm
21 day preharvest interval through 1
pound per acre for foliar applica-
tion or soil application (band or
broadcast).
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
III-057901-9
35
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-mCHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Brussels Sprouts cluster (continued)
ITBJAHA Imported cabbage- 0.5-1 Ib/A
worm (6 Ib/gal
ITBCCBA Variegated cutworm SC/L)
(50-80% SC/S)
ITBCCRA Western yellow- 0.5 Ib/A
striped armyworm (6 Ib/gal
SC/L)
(50-60% SC/S)
ITBCCFA Armyworm 1 Ib/A Soil application (band). Apply over
ITBCCNA Beet armyworm (5% 0) the row and around base of plants.
IVAHAAA Crickets (including (3-5% G)
mole crickets) [Bait] Broadcast soil application. May be
ITBCABA Cutworms (climbing applied by aircraft. For fields
and surface feed- with previous Infestations or sus-
ing including pected infestations of cutworms,
black cutworm, apply prior to or just after plant-
granulate cut- ing.
worm, variegated
cutworm, western
bean cutworm)
ITABACA Saltmarsh cater-
pillar
ITBCCRA Western yellow-
striped armyworm
Issued: 3-22-82 III-057901-lO
36
-------
/14003AA
ITBCCNA
IOAAAEA
IQAMARA
ITABACA
ITBCCBA
ITBCCRA
ITBCCNA
IQAMARA
IOAAAEA
ITBCCBA
ITABACA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l^IYDROXYETHYL)PHOSPHONATE
Site and Pest
Carrot
Beet armyworm
Dipterous leaf-
miners
Lygus bugs
Saltmarsh cater-
pillar
Variegated cutworm
Western yellow-
striped armyworm
Beet armyworm
Lygus bugs
Dipterous leaf-
miners
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.1 ppm
28 day prebarvest interval through
1.5 pounds per acre for foliar ap-
plication.
Do not harvest tops for food or
feed.
1-1.5 Ib/A
(3-5% D)
Foliar application.
by aircraft.
May be applied
1-1.5 Ib/A
6 Ib/gal
SC/L)
(50-80% SC/S)
1 Ib/A
6 Ib/gal
SC/L)
(50-80% SC/S)
Variegated cutworm 0.5-1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
Saltmarsh cater-
pillar
1.5 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
Issued: 3-22-82
III-057901-ll
37
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Carrot (continued)
ITBCCRA Western yellow- 0.5 Ib/A
striped armyworm (6 Ib/gal
SC/L)
(50-80% SC/S)
Cauliflower See Brussels Sprouts cluster.
/02000AA Citrus Fruits 0.1 ppm
2.5 ppm (in dried citrus pulp)
7 day preharvest interval through 4
pounds per acre for foliar applica-
tion. Apply only 1 application by
aircraft.
21 day preharvest interval through 4
pounds per acre for foliar applica-
tion. Do not make more than 3 ap-
plications during the fruiting peri-
od, 1 by aircraft and not more than
2 additional applications by ground
equipment.
Apply in a minimum of 1 gallon of
water per acre by aircraft or in 200
to 250 gallons of water per acre by
ground equipment.
ITAPAJA Avocado leafroller 4 Ib/A Use limited to CA.
ITBCCUA Citrus cutworm (50-80% SC/S) Foliar application.
ITANAXA Citrus looper
ITBUALA Orange tortrix
ITBHAFA Black swallowtail 2 Ib/A
ITBUAGA Fruittree leaf- (50-80% SC/S)
roller
ITBUBCA Omnivorous leaf-
roller
Issued: 3-22-82 111-057901-12
38
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
/23003AA
/28079AA
Site and Pest
Clover
Clover-Grass Mixture
Dosages and Tolerance, Use, Limitations
Formulation(s)
60 ppm (fresh)
90 ppm (hay)
No pregrazlng or preharvest interval
through 1 pound per acre of spray
formulations for foliar application.
Do not make more than 3 applications
per cutting.
7 day pregrazing or preharvest in-
terval through 1 pound per acre of
dust formulations for foliar appli-
cation.
Use patterns for spray formulations
include clover in mixed stands with
ITBJADA
Alfalfa caterpillar 0.375-0.5
Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
grasses.
Foliar application.
by aircraft.
May be applied
ITBMBUA
Alfalfa webworm
ITBCCFA
IQAMABA
IQAMARA
IQAQAAA
ITBCCNA
IRAFAAA
ITBCCBA
ITBCCRA
Armyworm
Alfalfa plant bug
Lygus bugs (includ-
ing tarnished
plant bug)
Stink bugs
Beet armyworm
Leafhoppers
Variegated cutworm
Western yellow-
striped armyworm
(50-80% SC/S)
0.25-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
Issued: 3-22-82
III-057901-13
39
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXyETHYL)PHOSPHONATE
Site and Pest
/23003AA
ITBJADA
ITBMBUA
ITBCCNA
IQAMARA
IQAQAAA
ITBCCBA
ITBCCRA
ITBCCFA
/13009AA
/13020AA
ITBCCFA
ITBMBWA
1TBWAFA
IOAAAEA
ITABACA
IMQAAAA
ITBCCBA
Dosages and Tolerance, Use, limitations
Formulation(s)
Clover cluster (continued)
(Clover)
Alfalfa caterpillar 1 Ib/A
Alfalfa webworm (5-8% D)
Beet armyworm
Lygus bugs (Includ-
ing tarnished
plant bug)
Stink bugs
Variegated cutworm
Western yellow-
striped armyworm
Foliar application. May be applied
by aircraft.
Armyworm
1 Ib/A
(5% P/T)
[Bait]
Broadcast soil application. Make 1
application per cutting.
Clover (seed crop) See Alfalfa (seed crop) cluster.
Clover-Grass Mixture See Clover cluster.
Collards
Lettuce
0.1 ppm
28 day preharvest interval through 1
pound per acre for foliar applica-
tion or soil application (band or
broadcast).
For lettuce, do not apply after
heads begin to form.
Armyworm
Beet webworm
Diamondback moth
Dipterous leaf-
miners
Saltmarsh cater-
pillar
Thrips
Variegated cutworm
1 Ib/A
(3-8% D)
(6 Ib/gal
SC/L)
(50-60% SC/S)
1 Ib/A
(3-8% D)
or
0.5-1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
111-057901-14
40
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONAIE
Site and Pest Dosages and Tolerance. Use, Limitations
Formulation(s)
Collards cluster (continued)
ITBCCFA Armyworm 1-1.5 Ib/A
ITBCCNA Beet armyworm (5Z D)
IVAHAAA Crickets (including (3-52 6)
mole crickets) [Bait]
ITBCABA Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
INBUAAA Darkling beetles
ITABACA Saltmarsh cater-
pillar
ITBCCRA Western yellow-
striped armyworm
/28006AA Corn. Field
/15004AA Corn. Pop
/15005AA Com. Sweet
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
0.1 ppm (corn grain including pop-
corn, fresh corn including sweet
corn [kernels plus cob with husk re-
moved])
30 ppm (fodder, forage)
No preharvest interval through 1
pound per acre of spray formulations
for foliar and soil applications.
Do not make more than 3 applications
during the growing season.
28 day preharvest interval through 1
pound per acre of 80 percent soluble
concentrate/solid formulation for
food, feed, or ensilage for foliar
and soil applications.
40 day preharvest interval through 1
pound per acre of bait formulations
for feed, food, or ensilage for soil
application (band or broadcast). Do
not make more than 1 application
during the growing season.
Issued: 3-22-82
111-057901-15
41
-------
ITBCCFA
IVAHAAA
ITBCABA
INBUAAA
ITABACA
ITBCCFA
ITBCABA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Corn, Field cluster (continued)
Armyworm
Crickets
Cutworms (climbing
and surface
feeding)
Darkling beetles
Saltmarsh cater-
pillar
Armyworm
Cutworms
1 Ib/A
(5% D)
(3-5% G)
[Bait]
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
0.5-1 Ib/A Foliar and soil application. For
(4-6 Ib/gal early applications, when plants are
SC/L) 3 to 12 inches high, direct spray to
(40.5% lower portion of plants and to the
SC/L)*** soil around the base of plants.
(50-80% SC/S) Later applications may be made as
full coverage sprays.
Corn, Field
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
/28007AA
ITBCCNA
IQAMBFA
IQAMAYA
ITAYAHA
I1BCAOA
Corn, Sweet
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
Cotton
Beet armyworm
Black cotton flea-
hopper complex
Cotton fleahopper
Cotton leafperfor-
ator
Cotton leafworm
Issued: 3-22-82
0.9-1.5 Ib/A
(3-8% D)
0.1 ppm (cottonseed)
7 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast).
14 day pregrazing interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast).
May cause marginal leaf burn. In-
jury may occur if application is
made while foliage is wet.
Foliar application. May be applied
by aircraft. For beet armyworm,
cotton leafworm, and western yellow-
striped armyworm, apply the lower
rate. For other pests, apply the
range.
111-057901-16
42
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
INBUAAA
IMAAAEA
IQAMARA
ITABACA
IRAFALA
IQAQAAA
ITBCCRA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
ITABACA
1TBCCRA
ITBCCNA
IRAFALA
IQAMBFA
ITAYAHA
IMAAAEA
IQAMARA
IQAQAAA
Site and Pest
Cotton (continued)
Dosages and Tolerance, Use, Limitations
Formulation(s)
Pest list continued from previous page.
Darkling beetles
Leafrollers
Lygus bugs
Saltmarsh cater-
pillar
Southern garden
leafhopper
Stink bugs
Western yellow-
striped armyworm
Armyworm 1.5 Ib/A
Beet armyworm (5% D)
Crickets (including (3-5% G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Beet armyworm
Southern garden
leafhopper
Black cotton flea-
hopper complex
Cotton leafperfor-
ator
Leafrollers
Lygus bugs
Stink bugs
1 Ib/A
(4 Ib/gal
SC/L)
(40.5%
SC/L)***
Foliar application. May be applied
by aircraft. For cotton fleahopper,
apply lower rate for light to moder-
ate infestation. Higher rates may
be required if heavy infestation or
(50-80% SC/S) migration occurs.
1-1.5 Ib/A
(4 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
Issued: 3-22-82
111-057901-17
43
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
IQAMAYA
ITBCAOA
INBUAAA
ITBCCRA
ITABACA
IQAMAYA
IQAMARA
/28049AA
/28052AA
ITBCCFA
IVAHAAA
ITABACA
ITBCCXA
Site and Pest
Cotton (continued)
Cotton fleahopper
Cotton leafworm
Darkling beetles
Western yellow-
striped army worm
Saltmarsh cater-
pillar
Cotton fleahopper
Lygus bugs
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.25-1 Ib/A
(4 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5-1 Ib/A
(4 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
1.5 Ib/A
(4 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.25-0.5 Ib/A Ultra low volume foliar application.
(4 Ib/gal Apply by aircraft or ground equip-
SC/L) ment.
Cucumbers
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
Field Crops
Truck Crops
Armyworm
(Crickets)
Saltmarsh cater-
pillar
Surface feeding
cutworms
Flax
Lettuce
Oats
Issued: 3-22-82
N.F.
Applications should be made to the
soil, away from, and not in contact
with the crop.
7.5 lb/ Soil application to field borders
1,000 ft (band). To control migrating cater-
(5% D) pillars, place a band 6 inches wide
(4-5% G) and 0.125 to 0.25 inch deep around
the field to be protected. Use in
conjunction with an aluminum or
fiber strip barrier.
See Barley cluster.
See Collards cluster.
See Barley cluster.
111-057901-18
44
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
./23035AA
/28045AA
Site and Pest
Pastures (grass)
ITBCCFA
ITBCCOA
Armywoim
Fall armyworm
ITBCCFA
ITBCCOA
IQAMAAA
IRAFAAA
ITBNAJA
ITBNAJC
Armyworm
Fall armyworm
Plant bugs
Leafhoppers
Range caterpillar
Range caterpillar
(larvae)
Dosages and Tolerance, Use, Limitations
Formulation(s)
60 ppm (fresh)
90 ppm (hay)
No preharvest interval through 1
pound per acre for foliar applica-
tion. Do not make more than 3 ap-
plications per cutting or per grow-
ing season if crop is not cut for
hay.
No preharvest interval through 1
pound per acre for ultra low volume
application. Do not make more than
1 application per cutting if crop is
not cut for hay, except that a sec-
ond application may be made at 0.25
to 0.5 pound per acre, if needed.
Do not apply more than a total of 1
pound per acre in a single growing
season on crops not cut for hay.
Applications may be made without re-
moval of grazing livestock.
0.25-1 Ib/A
(4 Ib/gal
SC/L)
1 Ib/A
(4 Ib/gal
SC/L)
(50-80% SC/S)
0.5-1 Ib/A
(4 Ib/gal
SC/L)
(50-80% SC/S)
Foliar application. Dosage recom-
mended for Southeast and South Cen-
tral States. May be applied by air-
craft. Apply higher rate when In-
festation is heavy and/or the larvae
are in the late instar stages of
growth.
Foliar application. May be applied
by aircraft. Some 4 pounds per gal-
lon soluble concentrate/liquid for-
mulations may be applied undiluted
as an ultra low volume spray by air-
craft or ground equipment.
0.25-0.5 Ib/A Use limited to NM.
(4 Ib/gal Foliar application. May be applied
SC/L)
by aircraft. May be applied undi-
luted as an ultra low volume spray
by aircraft or ground equipment.
Apply during first through third
instars only.
Issued: 3-22-82
111-057901-19
45
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-mCHLORO-l-HYDROXYETHYL)PHOSPHONATE
/28015AA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
ITABACA
ITBCCRA
/15008AA
ITBCCFA
IOAAAEA
ITBJAHA
IQAMARA
INAPAFA
IQAQAAA
ITBCCBA
ITBCBTA
Site and Pest
Peanuts
Dosages and Tolerance,
Fonnulatlon(s)
Use, Limitations
Armyworm 1 lb/A
Beet armyworm (5% D)
Crickets (including (4-5% 6)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped army worm
Peas, Field (blackeyed peas,
cowpeas, crowder peas, and
southern peas)
1-1.5 lb/A
(3-8% D)
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
0.05 ppm (peanuts)
4 ppm (peanut vine hay and hulls)
No preharvest interval through 1
pound per acre for soil application
(band or broadcast). Do not make
more than 3 applications before dig-
ging. One additional application
may be made between digging and har-
vest.
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
0.1 ppm (cowpeas)
1 ppm (vines)
14 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast). Do not make more
than 2 applications during the grow-
ing season.
Armyworm
Dipterous leaf-
mlners
Imported cabbage-
worm
Lygus bugs
Mexican bean beetle (50-80% SC/S)
Stink bugs
Variegated cutworm
Western bean cut-
worm
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
111-057901-20
46
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
ITABACA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
ITABACA
ITBCCRA
/28017AA
IOAAAEA
IOBMATA
IOABADA
ITBCCFA
IVAHAAA
INBUAAA
ITABACA
Site and Pest
Dosages and Tolerance. Use. Limitations
Formulation (s)
Peas, Field (blackeyed peas, cowpeas, crowder peas, and southern peas)
(continued)
Saltmarsh cater-
pillar
1.5 Ib/A
(6 Ib/gal
SC/L)
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Armyworm 1-1.5 Ib/A
Beet armyworm (5% D)
Crickets (including (4-5% G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Peas
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
Peppers
0.1 ppm
21 day preharvest interval through 1
pound per acre of spray or bait for-
mulations or through 1.25 pounds per
acre of dust formulations of foliar
application or soil application
(band or broadcast).
Dipterous leaf-
miners
Pepper maggot
Serpentine leaf-
miner complex
Armyworm
Crickets
Darkling beetles
Saltmarsh cater-
pillar
Issued: 3-22-82
1-1.25 Ib/A
(3-8% D)
or
1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
1 Ib/A
(5% D)
(3.5-5% G)
[Bait]
Foliar application.
by aircraft.
May be applied
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
111-057901-21
47
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
ITBCCXA
/10011AA
IQAGAFA
ITBCCBA
IQAGAFA
ITBCCBA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
ITABACA
Site and Pest
Peppers (continued)
Surface feeding
cutworms
Dosages and Tolerance, Use, Limitations
Formulation(s)
with previous infestations or sus-
pected infestations of surface feed-
ing cutworms, apply prior to or just
after planting.
Peppers
(greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
Pumpkin
0.1 ppm
14 day preharvest interval through 1
pound per acre of spray or bait for-
mulations or 1.5 pounds per acre of
dust formulation for foliar applica-
tion or soil application (band or
broadcast). Do not make more than 1
application during the growing sea-
Squash bug
Variegated cutworm
Squash bug
Variegated cutworm
son.
1.25-1.5 Ib/A Foliar application.
(3-8% D) by aircraft.
1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
0.5-1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
May be applied
Armyworm 1 Ib/A
Beet armyworm (5% D)
Crickets (including (4-5% G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing Including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Issued: 3-22-82
111-057901-22
48
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Pumpkin (continued)
Dosages and Tolerance, Use, Limitations
Formulation(s)
Pest list continued from previous page.
ITBCCRA
/28045AA
Western yellow-
striped armyworm
Rangeland (grass)
ITBNAJA
Range caterpillar
240 ppm (forage and hay)
No preharvest interval through 0.5
pound per acre of ultra low volume
liquid formulations in oil for foli-
ar application. Do not make more
than 3 applications during growing
season.
No preharvest interval through 1
pound per acre of dilute spray or
ultra low volume formulations for
foliar application. For dilute
sprays do not make more than 3 ap-
plications per cutting or per grow-
ing season if grass is not cut for
hay. For ultra low volume sprays do
not make more than 1 application per
cutting or per growing season if
grass is not cut for hay.
Applications may be made without re-
moval of livestock.
0.25-0.5 Ib/A Ultra low volume foliar application.
(1.5 Ib/gal Apply by aircraft. Apply to active-
RTU)
ly feeding and mobile larvae in the
third through fifth instars. A sec-
ond application may be made if need-
ed.
Also refer to Pasture (grass) for additional pest
and use information.
Issued: 3-22-82
111-057901-23
49
-------
/28076AA
ITBCCFA
IQAMARA
IMOAAAA
ITBCCBA
ITBCCFA
IVAHAAA
ITABACA
ITBCCXA
/28023BA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
ITABACA
ITBCCRA
ITBCCFA
IOAAAEA
IXBJAHA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Safflower 0.1 ppm (seed)
Apply up to the onset of bloom
through 1.5 pounds per acre for fo-
liar application or soil application
(band or broadcast). Do not make
more than 2 applications during the
growing season.
Do not apply after onset of bloom.
Armyworm 1.25-1.5 Ib/A Foliar application. May be applied
Lygus bugs (3-8% D) by aircraft. Apply approximately 14
Thrips or days prior to bloom and repeat at
Variegated cutworm 1-1.5 Ib/A onset of bloom.
(50-80% SC/S)
Armyworm
Crickets
Saltmarsh cater-
pillar
Surface feeding
cutworms
1.5 Ib/A
(5% D)
(4-5% G)
[Bait]
Soybeans (seed crop)
Armyworm 1-1.5 Ib/A
Beet annyworm (5% D)
Crickets (including (4-5% G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Armyworm 1.25-1.75
Dipterous leaf- Ib/A
miner (5% D)
Imported cabbage- or
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of surface feed-
ing cutworms, apply prior to or just
after planting.
N.F.
Do not pasture or harvest treated
crop for feed, food, forage, or oil.
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
111-057901-24
50
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
IQAMARA
IQAQAAA
ITBCCBA
/28020AA
ITBMBUA
ITBCCNA
ITBMBWA
lOAAAEA
ITABACA
ITBCCBA
ITBMBUA
ITBCCNA
ITABACA
ITBMBWA
ITBCCBA
Dosages and Tolerance, Use, Limitations
Formulation(s)
Soybeans (seed crop) (continued)
worm 1-1.5 Ib/A
Lygus bugs (6 Ib/gal
Stink bugs SC/L)
Variegated cutworm (50-80% SC/S)
Spinach (greenhouse research crops)
See Bean, Lima (greenhouse research crops)
cluster.
Sugar Beets
Alfalfa webworm
Beet armyworm
Beet webworm
Dipterous leaf-
miners
Saltmarsh cater-
pillar
Variegated cutworm
Alfalfa webworm
Beet armyworm
Saltmarsh cater-
pillar
Beet webworm
Variegated cutworm
1-1.5 Ib/A
(3-8% D)
1-1.5 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.5-1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
0.1 ppm
12 ppm (tops)
14 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast) if tops are not to be
fed to livestock.
28 day preharvest interval through
1.5 pounds per acre for foliar ap-
plication or soil application (band
or broadcast) if tops are to be fed
to livestock.
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
111-057901-25
51
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
IOAAAEA
ITBCCFA
IVAHAAA
ITBCABA
INBUAAA
ITABACA
ITBCCXA
/26003AA
ITBCBNA
ITBRAKA
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
Dosages and Tolerance, Use, Limitations
Formulatlon(s)
Sugar Beets (continued)
Dipterous leaf-
miners
Armyworm
Crickets
Cutworms (climbing
and surface feed-
ing including
black cutworm,
granulate cut-
Darkling beetles
Saltmarsh cater-
pillar
Surface feeding
cutworms
Tobacco
Tobacco budworm
Tobacco hornworm
1 Ib/A
(4-6 Ib/gal
SC/L)
(40.5%
SC/L)***
(50-80% SC/S)
1-1.5 Ib/A
(5% D)
(3-5% G)
[Bait]
1 Ib/A
(5% P/T)
[Bait]
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
Broadcast soil application.
N.F.
3 day preharvest interval through 1
pound per acre of spray formulations
or 1.5 pounds per acre of dust and
granular formulations for foliar ap-
plication.
Do not apply bait formulations after
plants are 2 feet tall.
1-1.5 Ib/A Foliar application. For budworm,
(5-8% D) apply directly into bud. Repeat as
or needed.
0.4-0.6 Ib/A
(4% G)
or
1 Ib/A
(50-80% SC/S)
Armyworm
Beet armyworm
Crickets (including
mole crickets)
Cutworms (climbing
and surface feed-
ing including
black cutworm,
Issued: 3-22-82
1 Ib/A
(5% D)
(4-5% G)
[Bait]
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous infestations or sus-
pected infestations of cutworms, ap-
ply prior to or just after planting.
111-057901-26
52
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
ITABACA
ITBCCRA
/26003DA
INBPALC
/11005AA
ITBCCFA
IOAAAEA
IOABADA
ITSRAJA
IOAAAEA
IOABADA
IIBRAJA
Site and Pest
Tobacco (continued)
Dosages and Tolerance, Use, Limitations
Formulation(s)
Pest list continued from previous page.
granulate cut-
worm, variegated
cutworm, western
bean cutworm)
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Tobacco (to be transplanted)
Green June beetle 0.5 lb/
(larvae) 100 gal/
100 sq.yd
(50-80% SC/S)
Tomato
Armyworm
Dipterous leaf-
miners
Serpentine leaf-
miner complex
Tomato hornworm
Dipterous leaf-
miners
Serpentine leaf-
miner complex
Tomato hornworm
1-1.25 Ib/A
(3-8% D)
1 Ib/A
(6 Ib/gal
SC/L)
(50-80% SC/S)
Soil application. Apply to uprooted
areas of plant beds.
0.1 ppm
No preharvest interval through 1.25
pounds per acre of dust formulations
for foliar application to tomatoes
to be cooked (canning) before mar-
keting .
21 day preharvest interval through 1
pound per acre of spray formulations
or 1.25 pounds per acre of dust for-
mulations for foliar application.
28 day preharvest interval through 1
pound per acre of bait formulations
for soil application (band or broad-
cast).
Do not graze fields treated with
bait formulations.
Foliar application.
by aircraft.
May be applied
Issued: 3-22-82
111-057901-27
53
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-1-HYDROXYETHYL)PHOSPHONAIE
ITBCCFA
ITBCCNA
IVAHAAA
ITBCABA
INBUAAA
ITABACA
ITBCCRA
Site and Pest
Tomato (continued)
Dosages and Tolerance, Use, Limitations
Formulation(s)
Armyworm 1 Ib/A
Beet armyworm (5% D)
Crickets (including (3-5Z G)
mole crickets) [Bait]
Cutworms (climbing
and surface feed-
Ing including
black cutworm,
granulate cut-
granulated cut-
worm, variegated
cutworm, western
bean cutworm)
Darkling beetles
Saltmarsh cater-
pillar
Western yellow-
striped armyworm
Soil application (band). Apply over
the row and around base of plants.
Broadcast soil application. May be
applied by aircraft. For fields
with previous Infestations or sus-
pected infestations of cutworms,
apply prior to or just after plant-
ing.
See Field Crops cluster.
See Barley cluster.
Issued: 3-22-82
111-057901-28
54
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
LIVESTOCK AND POULTRY
Dosages and Tolerance, Use, Limitations
Formulation(s)
General Warnings and Limitations: Do not treat lactating dairy cattle,
animals less than 3 months old (unless otherwise specified), convalescent,
or stressed livestock. Do not apply in conjunction with oral drenches, or
other internal medications, or with other organic phosphates, or materials
having cholinesterase inhibiting activity.
/50004IA
/53001IA
(Dairy Animals)
Dairy Cattle (non-lactating)
IOAWABA
IMAAADA
Cattle grubs (in-
cluding common
cattle grub and
northern cattle
grub)
(Lice)
0.5 fl.oz 8%
RTU/100 Ib
body wt.
(8% RTU)
0.1 ppm (meat, fat and meat bypro-
ducts of cattle)
0.01 ppm (milk)
7 day prefreshening interval through
0.5 fluid ounce of 8 percent ready-
to-use formulation per 100 pound
body weight for pour on application.
Do not apply more than 4 fluid oun-
ces of 8 percent ready-to-use formu-
lation per animal. If freshening
occurs within 7 days after treat-
ment, do not use milk for human con-
sumption for the balance of the 7
day interval.
21 day preslaughter interval through
0.5 fluid ounce of 8 percent ready-
to-use formulation per 100 pound
body weight for pour on application.
Animal treatment. Pour on applica-
tion. Apply a single treatment
along the backline. Proper timing
of treatment is important. Treat
cattle as soon as possible after fly
activity ceases. Host parasite re-
actions sometimes occur when cattle
are treated while the common cattle
grub is in the gullet, or while the
northern cattle grub is in the area
of the spinal cord. Consult your
veterinarian, extension livestock
specialist, or extension entomolo-
gist regarding timing of treatment.
If it is impossible to determine the
origin of the cattle, and thus the
exact stage of the grubs is unknown,
feed only a maintenance ration of
low energy feed during the treatment
period. This lessens the likelihood
of severe bloat which may occur in
Issued: 3-22-82
111-057901-29
55
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, T.I mi tat Ions
Formulatlon(s)
Dairy Cattle (non-lactatlng) (continued)
/530011A
(Livestock Intended for Slaughter)
Beef Cattle
IOAWABA
Cattle grubs (In-
cluding common
cattle grub and
northern cattle
grub)
8 lb/100 gal
(80% SC/S)
cattle on full feed when the common
cattle grub Is killed while In the
gullet. Do not treat animals for 10
days before or after shipping or
weaning, or after exposure to conta-
gious or Infectious diseases.
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle)
0.01 ppm (milk)
14 day preslaughter Interval through
8 pounds of soluble concentrate/
solid formulation per 100 gallons of
water for animal spray application.
Do not apply more than 4 fluid oun-
ces of 8 percent ready to use formu-
lation per animal.
Animal spray treatment. Apply a
single treatment with high pressure
(250 to 350 pounds per square Inch)
to thoroughly wet the skin. Operate
box-type spray chutes at maximum
pressure. Do not spray in a con-
fined, nonventilated area. Proper
timing of treatment is important.
Treat cattle as soon as possible
after fly activity ceases. Host
parasite reactions sometimes occur
when cattle are treated while the
common cattle grub is in the gullet,
or while the northern cattle grub is
in the area of the spinal cord.
Consult your veterinarian, extension
livestock specialist, or extension
entomologist regarding timing of
treatment. If it is impossible to
determine the origin of the cattle,
and thus the exact stage of the
grubs is unknown, feed only a main-
tenance ration of low energy feed
Issued: 3-22-82
111-057901-30
56
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Beef Cattle (continued)
during the treatment period. This
lessens the likelihood of severe
bloat which may occur in cattle on
full feed when the common cattle
grub is killed while in the gullet.
Do not treat animals for 10 days be-
fore or after shipping or weaning,
or after exposure to contagious or
infectious diseases.
IQAUADA
IMAAADA
Horn fly
Lice
8 lb/100 gal
(80% SC/S)
spray treatment. Apply to
the point of run off. Repeat as
needed.
Refer to (Dairy Animal's), Dairy Cattle (non-lac-
tating) for additional information.
(Livestock Not Intended for Slaughter)
/56005IA
Horses
IOASAAA
Horse bots
0.1 ppm (meat, fat, and meat bypro-
ducts of horses)
Do not treat horses to be slaugh-
tered for food. Do not treat sick
or debilitated horses, mares in the
last month of pregnancy, or colts
under 4 months of age. Do not
administer in conjunction with or
for 10 to 14 days (depending upon
the product) before or after treat-
ment with other organic phosphates
or chollnesterase inhibitors.
Symptoms of overdosage are ataxia
and colic.
9 g/5-10 Animal treatment. Administer by
fl.oz/500 Ib stomach tube or drench. The suspen-
body wt. sion may be stored for 24 hours.
(37.8% WP/D) Prepare doses individually. Repeat
at 30 day intervals as needed.
Formulated with thiabendazole.
9 g/500 Ib
body wt.
(37.8% WP/D)
(37.8-90%
P/T)
Animal treatment. Administer dry or
dissolved in water. Mix with the
amount of feed to be consumed at 1
feeding. Withdrawal of feed 12 to
18 hours prior to treatment will
assure complete ingestlon. Repeat
at 90 to 120 day intervals. Do not
Issued: 3-22-82
111-057901-31
57
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Horses (continued)
Dosages and Tolerance, Use, Limitations
Formulation(s)
repeat treatment more frequently
than every 30 days. Do not admin-
ister intravenous anesthetics,
especially muscle relaxant, for a
period of 14 days after treatment.
May be formulated with thiabenda-
zole.
AGRICULTURAL PREMISES AND EQUIPMENT
General Warnings and Limitations; Good sanitation is a necessary part of
any house fly control program. Direct application to walls, floors, or
other surfaces previously treated with lime, whitewash, or other alkaline
materials may be ineffective. On limed floors, where floors are lacking,
or where there is not enough clean floor space available, treat and dis-
tribute bait on sacking, boards, or cardboard strips. Dry and liquid
baits may be applied daily, if needed, until flies are controlled. Do not
contaminate milk or milk handling equipment. Do not contaminate feed,
drinking water, litter, and feed troughs. Do not treat portions of build-
ings where animals can lick the treated surface.
(Dairy Barns Including Milk Rooms. Equipment and Barnyards)
/50000JA
/60004JA
/53000JA
/52000JA
IVAAABA
IOAUAFA
Dairy Barns
Milking Rooms
Cockroaches
House fly
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle)
0.01 ppm (milk)
0.032-0.04 oz Premise treatment. Dry bait. Scat-
/1,000 sq.ft ter directly on areas where pests
(0.4-12 G) breed or congregate. Scatter light-
ly on floors, alleyways, window
sills, and other clean horizontal
surfaces. For faster results, apply
to a moistened surface.
0.16 oz/gal
(1% G)
Premise treatment. Liquid bait.
Mix with 1 pound of sugar or 2 cups
of corn syrup. Sprinkle on floors,
alleyways, window sills, and other
areas where pests congregate.
Issued: 3-22-82
111-057901-32
58
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TBULCHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Dairy Barns cluster (continued)
Syrup bait
(1% G)
/50000KA
/60004KA
/53000KA
/52000KA
IVAAABA
IQAUAFA
Dairy Barns (manure treatment)
Milking Rooms (manure treatment)
Cockroaches
House fly
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
/890030A
IVAAABA
IOAUAFA
Garbage Dumps (dairy barn and
milking room premises)
Cockroaches
House fly
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
Premise treatment. Apply in suffi-
cient water to make a syrup. Brush
onto vertical surfaces, ceiling
cracks, and rafters where pests con-
gregate. For flies in areas not
clean enough, apply to sacks,
boards, or strips of cardboard and
place them inside or outside build-
ings where pests congregate.
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle)
0.01 ppm (milk)
Manure treatment. Dry bait. Scat-
ter directly onto manure where pests
breed or congregate.
Manure spot treatment. Liquid bait.
Mix with 1 pound of sugar or 2 cups
of corn syrup. Sprinkle directly
onto manure where pests breed or
congregate.
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle)
0.01 ppm (milk)
Dry bait. Scatter directly onto
garbage dumps where pests breed or
congregate.
Liquid bait. Mix with 1 pound of
sugar or 2 cups of corn syrup.
Sprinkle directly on garbage dumps
where pests breed or congregate.
Issued: 3-22-82
111-057901-33
59
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
(Animal Buildings, Equipment and Outdoor Areas For Other Than Dairy,
Poultry and Pets)
/53000JA
IOAUAFA
Animal Buildings (including
barns, shelters, and stables)
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle, goats, horses, and
sheep)
House fly
12 impr waxed Bait application. Dip tray in water
tray before attaching tray under garbage
(12 Impr) can lids or hanging on walls out-
doors where pests accumulate. Keep
waxed tray moist.
4 lb/40 gal Premise residual spray treatment.
[2 gal/1,000 Remove animals before spraying. Ap-
sq.ft] ply in and around buildings and
(80Z SC/S) stock pens. Apply to ceilings,
floors, walls, and other areas where
flies breed and congregate. Repeat
as needed, but not more frequently
than 4 to 14 day intervals. For
longer residual activity, add 1
pound of sugar per gallon of spray.
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Dairy Barns cluster for addi-
tional information.
/53000KA
Animal Buildings (manure treatment)
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Dairy Barns (manure treat-
ment) cluster.
/890030A
IOAUAFA
Garbage Dumps (animal building
premises)
0.1 ppm (meat, fat, and meat bypro-
ducts of cattle, goats, horses, and
sheep)
House fly
1% impr waxed Bait application. Dip tray in water
tray before attaching tray under garbage
(12 Impr) can lids or hanging on walls out-
doors where pests accumulate. Keep
waxed tray moist.
Issued: 3-22-82
III-057901-34
60
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONAIE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulatlon(s)
Garbage Dumps (animal building premises) (continued)
4 lb/40 gal Premise residual spray treatment.
[2 gal/1,000 Apply to refuse, garbage dumps, and
sq.ft] other areas where flies breed and
(80% SC/S) congregate. Repeat as needed, but
not more frequently than 7 to 14 day
intervals. For longer residual ac-
tivity, add 1 pound of sugar per
gallon of spray.
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Garbage Dumps (dairy barn and
milking room premises) for additional information.
(Feed Lots, Holding Pens and Corrals)
/52000JA Feed Lots 0.1 ppm (meat, fat, and meat bypro-
/52000JA Pens ducts of cattle, goats, horses, and
sheep)
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Dairy Barns cluster.
/52000KA Feed Lots (manure treatment) 0.1 ppm (meat, fat, and meat bypro-
/52000KA Pens (manure treatment) ducts of cattle, goats, horses, and
sheep)
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Dairy Barns (manure treat-
ment) cluster.
/890030A Garbage Dumps (feed lots and pen 0.1 ppm (meat, fat, and meat bypro-
premises) ducts of cattle, goats, horses, and
sheep)
Refer to (Dairy Barns Including Milk Rooms, Equip-
ment and Barnyards), Garbage Dumps (dairy barn and
milking room premises) for additional information.
HUMAN. PETS AND OTHER ANIMALS
General Warnings and Limitations; Good sanitation is a necessary part of
any house fly control program. Do not treat portions of buildings or
areas where animals can lick the treated surface. Apply baits in areas
Inaccessible to children and animals. Do not contaminate feed or drinking
water.
Issued: 3-22-82 111-057901-35
61
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
/54000JA
/54003JA
IVAAABA
IOAUAFA
Site and Pest
Animal Hospitals
Cockroaches
House fly
Dosages and Tolerance, Use, Limitations
Formulation(s)
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
Syrup bait
(1% G)
/54029IA
/65031MA
Bait Fish and Goldfish
IIEAABA
IIAAABA
IDCAABA
Anchor worms
Fishlice
(argulus sp.)
Gill flukes
A concentra-
tion of 25
ppm in the
pond
(80% SC/S)
Premise treatment. Dry bait. Scat-
ter outside runways, on window
sills, on ledges, and other areas
where pests congregate. For caged
units, apply along edges of dropping
area. For faster results, apply to
a moistened surface.
Premise spot treatment. Mix with 1
pound of sugar or 2 cups of corn
syrup. Apply outside runways and
areas where pests congregate.
Premise spot treatment. Apply in
sufficient water to make a syrup.
Brush onto vertical surfaces and
areas where pests congregate.
Consult your State Fish and Game
Agency before applying this product
to public waters. Permits may be
required before treating such
waters. Apply when the water tem-
perature at the 2 foot level is 85 F
(29.4 C).
Water treatment to control fish
parasites. Mix in sufficient water
to permit even distribution over the
pond surface. Apply uniformly to
the pond surface by sprinkler can,
low pressure sprayer, or by metering
into the wake of a power driven
boat. Apply in a criss-cross pat-
tern covering the entire pond sur-
face.
For anchor worm and fishlice make 4
applications at 7 day intervals.
For gill flukes make 1 application.
Issued: 3-22-82
111-057901-36
62
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-mCHLORO-l-HYDROXYETHYL)PHOSPHONATE
/54002JA
/54003JA
IMNAAAA
Site and Pest
Cat Quarters
Dog Quarters
Fleas
Dosages and Tolerance, Use, Limitations
Formulation(s)
/54003IA
Dogs
/54003JA
IQAUAFA
Dog Kennels
House fly
/54002JA
IOAUAFA
Pet Kennels
House fly
40 g/gal
[1 gal/
1,000 sq.ft]
(80% SC/S)
Use limited to professional pest
control operators.
Premise treatment. Apply to yard
area and other areas frequented by
animals. Remove animals before
treatment and let deposit dry before
allowing animals back into treated
area. Repeat as needed.
This use only occurs on multiple
active ingredient labeling and has
not been included in this single
active ingredient entry. Refer to
appropriate labeling for use infor-
mation and limitations.
40 g/8.75 Ib Use limited to professional pest
sugar control operators.
[4 this/ Premise treatment. Dry bait. Scat-
1,000 sq.ft] ter on outside runways, on window
(80Z SC/S) sills, on ledges, and other areas
where pest congregate. Repeat as
needed.
40 g/gal Use limited to professional pest
[5 gal/ control operators.
1,000 sq.ft] Premise treatment. For longer re-
(80% SC/S) sidual control, mix with 1 pound of
sugar or molasses per gallon of wa-
ter. Apply as a spray or brush onto
areas where pest congregate.
Refer to Animal Hospitals for additional informa-
tion.
0.032 oz/
1,000 sq.ft
(0.4% G)
Premise treatment. Dry bait. Scat-
ter on areas where pest congregates.
Issued: 3-22-82
111-057901-37
63
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
ORNAMENTALS
Dosages and Tolerance. Use, Limitations
Formulation(s)
General Warnings and Limitations; Phytotoxlcity has occurred on certain
varieties of carnation, hydrangeas, and zinnias. When treating large
plantings of these flovers for the first time, treat a few plants and ob-
serve for 4 to 5 days before treating the entire planting. Do not handle
treated plants until spray deposit has dried.
(Ornamental Plants (herbaceous, woody shrubs, trees and vines))
/31142AA
IOBJAEA
Narcissus
Narcissus bulb fly
1 lb/100 gal/ Soil drench. Direct stream at base
1,000 ft row of plants at the beginning of adult
(6 Ib/gal activity (early May to June). Re-
SC/L) peat annually.
(50-80Z SC/S)
/32005AA
/35000AA
/630030A
ITAXAIB
Ornamental Evergreens
Ornamental Shade Trees
Gypsy moth (eggs)
2 oz 40.5% -
SC/L/gal
(40.5% SC/L)
Bark application. Treat egg masses
on tree trunks and limbs, under
bark, on fences, and in wood piles
and rock walls. Apply to the point
of run off, usually in April or
shortly before larval emergence.
Egg masses usually begin hatching in
mid-April, but can vary according to
location. Consult your State Agri-
cultural Extension Service for prop-
er timing of application in your
area.
Issued: 3-22-82
111-057901-38
64
-------
/3100QAA
/35000AA
/34000AA
ITBCCFA
ITBKABA
ITBCCZA
IQAAAEA
IQAMARA
IQAQAAA
IQAMATA
ITBCBNA
ITAAAMA
/31000AA
/31000DA
ITBCCFA
IVAHAAA
ITABACA
/35098AA
ITBGBLA
ITBMBCA
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use, Limitations
Formulation(a)
Ornamental Herbaceous Plants
(including annuals)
Ornamental Shade Trees
Ornamental Woody Shrubs and Vines
Annyworm
Bagworm
Climbing cutworms
Dipterous leaf-
miners
Lygus bugs
Stink bugs
Tarnished plant bug
Tobacco budworm
Webworms
(5% D)
or
0.167-0.25
oz**/gal
or
1-1.5 lb/
100 gal
(4-6 Ib/gal
SC/L)
(40.5Z
SC/L)***
(50-fiOZ SC/S)
Ornamental Herbaceous Plants (in-
cluding aster, chrysanthemum,
daisy, iris, and nursery stock)
Foliar application. For dust formu-
lation, apply to both upper and low-
er surfaces of leaves. For spray
formulations, apply until plants are
thoroughly wet. Repeat as needed.
Aimyworm
Crickets
Saltmarsh cater-
pillar
1-1.5 Ib/A
(5% G)
Foliar application.
Pine
Nantucket pine tip 0.167 oz**/
moth gal
Zimmerman pine moth or
1 lb/100 gal
(4-6 Ib/gal
SC/L)
(40.52
SC/L)***
(50-80% SC/S)
Foliar application. Apply until
plants are thoroughly wet. Repeat
as needed.
Issued: 3-22-82
111-057901-39
65
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONAIE
Site and Pest
Dosages and Tolerance. Use, Limitations
Formulation( s)
(Lawns and Turf (including ground covers))
/330100A
/330080A
Lawns
Ornamental Turf
ISASAAA
ITBCCFA
IQALAEA
IVAHAAA
ITBCABA
ITABACA
ITBMABA
Ants
Armyworm
Chinch bug
Crickets
Cutworms (including
surface feeding
cutworms)
Saltmarsh cater-
pillar
Sod webworm s
0.125-0.625
lb/5,000
sq.ft
(5-6.2Z G)
or
0.625-0.9375
lb/5,000
sq.ft
[up to
75-150 gal/
5,000 sq.ft]
(4-6 Ib/gal
SC/L)
(50Z SC/S)
or
0.375-0.9375
lb/5,000
sq.ft
[up to
75-150 gal/
5,000 sq.ft]
(80Z SC/S)
Do not graze or use clippings from
treated areas for feed or forage.
Keep children and pets off treated
areas until spray has dried for
spray formulations. After granular
application, water the lawn using
75 to 150 gallons of water per
5,000 square feet.
Application to established lawns and
turf. For sod webworms, mow lawn
and rake dead grass from damaged
areas. Water lawn and allow grass
to dry before spraying. Do not wat-
er again for at least 3 days. Apply
up to 3 applications at 21 to 28 day
intervals. Up to 3 applications may
be needed for maximum control. In
most areas, the first application
should be made in May or June. Con-
sult your State Agricultural Exten-
sion Service for more specific in-
formation.
ISASAVA
Texas harvester ant 0.67-1 cup
5Z G/mound
(5Z G)
Broadcast application over mound
surface. Inspect treated mound
regularly and repeat applications
as needed.
Issued: 3-22-82
111-057901-40
66
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance, Use, Limitations
Formulatlon(s)
Lawns cluster (continued)
INBPAAA
White grubs (in-
cluding Asiatic
garden beetle,
European chafer,
Japanese beetle,
May beetle, North-
ern masked chafer,
and Oriental
beetle)
0.9375 lb/
5,000 sq.ft
(5-6.2Z G)
or
0.9375 lb/
5,000 sq.ft
[up to
75-150 gal/
5,000 sq.ft]
(4 Ib/gal
SC/L)
(50-802 SC/S)
Application to established lawns and
turf. Apply when grubs are young
and actively feeding near the soil
surface usually during July and
August. Do not attempt to control
grubs in turf areas that have over
0.5 to 0.75 inch thatch build up
since heavy thatch (0.75 to 2 in-
ches) will prevent the insecticide
from penetrating down to the area
where pests are feeding. Remove
thatch before treating. A second
application may be needed for large
sized larvae. Thoroughly irrigate
turf immediately after application.
Irrigation may be postponed, based
on actual count and species of grub
present. Refer to 80 percent sol-
uble concentrate/solid formulation
labels for specific watering sched-
ule.
(Ornamental and Forest Greenhouse Plants)
/32008CA
Weed Hosts of Plant Pathogens
(greenhouse research crops)
This use only occurs on Special
Local Need (24(C)) labeling and has
not been included in this entry.
Refer to appropriate labeling for
use information and limitations.
Issued: 3-22-82
111-057901-41
67
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
FOREST, CHAPARRAL, NONAGRICULTURAL AND WASTELANDS
/30000AA
Forest Trees
ITAUAGA
ITAXAIC
Forest tent cater- 0.75 Ib/A
pillars (4 Ib/gal
SC/L)
Gypsy moth (larvae) 1 Ib/A
(4 Ib/gal
SC/L)
1 Ib/A
(1.5 Ib/gal
RTU)
ITBUASA
Spruce budworm
0.5-1 Ib/A
(4 Ib/gal
SC/L)
Do not apply directly to water or
wetlands except under the forest
canopy. Consult State Agricultural
Extension Service for proper timing
of application in the area infested.
Application of undiluted trichorphon
can cause spotting of automobile
paint surfaces if exposure is per-
mitted. If accidental exposure does
occur, the car should be washed im-
mediately.
Use limited to AL and LA.
Ultra low volume foliar application.
Apply undiluted by aircraft. Repeat
as needed.
Ultra low volume foliar application.
Apply undiluted by aircraft. Repeat
as needed.
Ultra low volume foliar application.
Apply by aircraft. Schedule appli-
cations in accordance with the rec-
ommendation of local gypsy moth con-
trol authorities. Repeat as needed.
Use limited to ME and NH.
Ultra low volume foliar application.
Apply undiluted by aircraft when ap-
proximately 50 percent of the larvae
are in the fourth instar. Repeat as
needed.
/65031MA
NQNCROP AQUATIC AREAS
Ponds
Consult your State Fish and Game
Agency before applying this product
to public waters. Permits may be
required before treating such
waters.
Refer to HUMAN, PETS AND OTHER ANIMALS, Bait Fish
and Goldfish, for additional information.
Issued: 3-22-82
111-057901-42
68
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-XRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance. Use, Limitations
Formulation(s)
DOMESTIC DWELLINGS. MEDICAL FACILITIES AND SCHOOLS
General Warnings and Limitations; Good sanitation is a necessary part of
any house fly control program. Do not contaminate food, drinking water,
or utensils. Do not allow children or pets in treated areas until sprayed
surfaces are dry. Apply baits in areas Inaccessible to children and pets.
Dry and liquid baits may be applied daily, if needed, until flies are con-
trolled.
/630010A
Domestic Dwellings (Indoor)
IQAFACA
Bed bug
40 g/gal
(80% SC/S)
IVAAABA
IVAHAAA
IMPBACA
Cockroaches
Crickets
Silverfish
Bait
(0.92-1% G)
40 g/19 Ib
sugar
or
0.46% dry
bait
(80% SC/S)
40 g/gal/
750 sq.ft
(80% SC/S)
The 80 percent soluble concentrate/
solid formulation is limited to pro-
fessional pest control operators.
Indoor treatment. Apply as a coarse
spray or brush onto baseboards,
cracks, and crevices. Treat beds
including a light application to
tufts and seams of mattresses. Do
not soak mattresses. Treated mat-
tresses should be aired for at least
8 hours or until dry. Do not treat
infant bedding or cribs.
Indoor treatment. Dry bait. Place
a small quantity on pieces of paper,
cardboard, or in shallow jar lids.
Place in protected areas such as in
closets, under sinks or refrigera-
tors, and where dying insects cannot
fall into food, utensils, or drink-
ing water. Any bait visible after
application should be carefully
brushed into cracks and crevices or
removed. Wet the bait slightly for
increased killing efficiency.
Indoor treatment. Dry bait. Apply
to areas where pests congregate.
Indoor spot treatment. For residual
control, apply ai a coarse spray or
brush onto baseboards, cracks, crev-
ices, and other areas where pests
hide or congregate. Repeat as need-
ed.
Issued: 3-22-82
111-057901-43
69
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use. Limitations
Formulatlon(s)
Domestic Dwellings (Indoor) (continued)
IMNAAAA
ILAAACA
Fleas
Ticks
40 g/gal/
750 sq.ft
(80Z SC/S)
Indoor treatment. Apply to infested
areas including rugs, draperies,
furniture, baseboards, cracks, crev-
ices, and all places where pests are
found. Before spraying fabric, test
spray on small hidden area to insure
that the spray will not stain. In
animal sleeping and holding areas,
remove old bedding and spray floor
thoroughly. Replace with fresh bed-
ding after spray dries. Do not
spray pets directly. Allow sprayed
areas to thoroughly dry before con-
tact. Repeat as needed.
/630030A
Domestic Dwellings (Outdoor)
ISASAAA
IVAHAAA
IMDAAAA
Ants
Crickets
Earwigs
IOAUAFA
House fly
The 80 percent soluble concentrate/
solid formulation is limited to pro-
fessional pest control operators.
0.4-0.8 oz/ Outdoor treatment. Dry bait. Apply
1,000 sq.ft around perimeter of building.
(5Z G)
0.32 oz/ Outdoor treatment. Dry bait. Apply
1,000 sq.ft lightly on ground, grass, near foun-
(1% G) datlon of house, along sidewalk and
driveway, around porches, doors and
other entrances to the house. Apply
in late afternoon and repeat at 14
day intervals as needed.
40 g/8.75 Ib Outdoor treatment. Dry bait. Apply
sugar to areas where pests congregate.
[4 this/ Repeat as needed.
1,000 sq.ft]
(80Z SC/S)
40 g/gal Outdoor treatment. Apply as a
[2.5-5 gal/ coarse spray or brush onto selected
1,000 sq.ft] surfaces where pest congregates.
(80% SC/S) Mix spray with 1 pound of sugar per
gallon for longer residual control.
On manure piles, apply the high
rate. Repeat at 7 to 14 day inter-
vals as needed.
Issued: 3-22-82
111-057901-44
70
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, T.imi tations
Formulation(s)
Domestic Dwellings (Outdoor) (continued)
ISASAVA
Texas harvester ant 0.67-1 cup
5% 6/mound
(5% G)
/890030A
IVAAABA
IOAUAFA
Garbage Dumps
Cockroaches
House fly
IOAUAFA
House fly
/880030A
IVAAABA
IOAUAFA
Latrines (Outdoor)
Cockroaches
House fly
Broadcast application over mound
surface. Inspect treated mound
regularly and repeat applicaions as
needed.
Refer to ORNAMENTALS, (Ornamental Plants (herba-
ceous, woody shrubs, trees and vines)), Ornamental
Evergreen cluster for additional information.
Refer to URBAN AND RURAL INDOOR/OUTDOOR AREAS
(PUBLIC HEALTH), Recreational Areas (including
Picnic Areas) for additional information.
0.04 oz/
1,000 sq.ft
(1Z G)
Dry bait. Scatter directly on gar-
bage dumps where pests breed or con-
gregate.
0.16 oz/gal Liquid bait. Mix with 1 pound of
(1% G) sugar or 2 cups of corn syrup.
Sprinkle directly on garbage dumps
where pests breed or congregate.
1% impr waxed Bait application. Dip tray in water
tray before attaching tray under garbage
(1% Impr) can lids or hanging on walls out-
doors where pests accumulate.. Keep
waxed tray moist.
40 g/gal Use limited to professional pest
[5 gal/ control operators.
1,000 sq.ft] Apply as a coarse spray. Mix spray
(80% SC/S) with 1 pound of sugar per gallon for
longer residual control. Repeat at
7 to 14 day intervals as needed.
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
Dry bait. Scatter lightly where
pests breed or congregate. For
faster results, apply to a mois-
tened surface.
Liquid bait. Spot treatment. Mix
with 1 pound of sugar or 2 cups of
corn syrup. Sprinkle where pests
congregate.
Issued: 3-22-82
111-057901-45
71
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest
Dosages and Tolerance. Use. Limitations
Formulation(s)
URBAN AND RURAL INDOOR/OUTDOOR AREAS (PUBLIC HEALTH)
/670020A
/630030A
IVAAABA
IQAUAFA
Recreational Areas (including
Picnic Areas)
Cockroaches
House fly
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
Syrup bait
(1% G)
Dry bait. Scatter lightly where
pests breed or congregate. For
faster results, apply to a moistened
surface.
Liquid bait. Mix with 1 pound of
sugar or 2 cups of corn syrup.
Sprinkle where pests congregate.
Syrup bait. Spot treatment. Mix in
enough water to make a syrup. Brush
on vertical surfaces and other areas
where pests congregate.
IQAUAFA
House fly
12 impr waxed Bait application. Dip tray in water
tray
(1% Impr)
/890030A
IVAAABA
IQAUAFA
Garbage Dumps (Recreational Area
Premises)
Cockroaches
House fly
0.04 oz/
1,000 sq.ft
(1% G)
0.16 oz/gal
(1% G)
before attaching tray under garbage
can lids or hanging on walls out-
doors where pests accumulate. Keep
waxed tray moist. Apply to areas
inaccessible to children and pets.
Dry bait. Scatter directly on gar-
bage dumps where pests breed or con-
gregate.
Liquid bait. Mix with 1 pound of
sugar or 2 cups of corn syrup.
Sprinkle directly on garbage dumps
where pests breed or congregate.
IQAUAFA
House fly
1% impr waxed Bait application. Dip tray in water
tray before attaching tray under garbage
(1% Impr) can lids or hanging on walls out-
doors where pests accumulate. Keep
waxed tray moist. Apply to areas
inaccessible to children and pets.
Issued: 3-22-82
111-057901-46
72
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use. Limitations
Formulation(s)
COMMERCIAL ESTABLISHMENTS
General Warnings and Limitations; Good sanitation is a necessary part of
any house fly control program. Baits may be used in edible product areas.
Do not use other formulations in edible product areas of food processing
plants, restaurants, or other areas where food is commercially prepared or
processed. Do not use in serving areas while food is exposed. Apply
baits in areas inaccessible to children and animals.
(Commercial Establishments (edible product areas))
/71009JB Poultry Packing Plants
/71008JB Red Meat Packing Plants Use limited to federally inspected
plants. Use only when the facility
is not in operation and food is not
exposed. Use only in bait boxes
where bait in each box can be ac-
counted for. Remove and account for
ail bait boxes prior to resuming
food processing.
IVAAABA Cockroaches 0.04 oz/ Indoor treatment. Dry bait.
IQAUAFA House fly 1,000 sq.ft
(1* G)
0.16 oz/gal Indoor treatment. Liquid bait. Mix
(1% G) with 1 pound of sugar or 2 cups of
corn syrup.
Syrup bait Indoor treatment. Syrup bait. Mix
(1% G) in enough water to make a syrup.
(Commercial Establishments (areas other than edible product))
General Warnings and Limitations; Do not treat cannery waste which may
be fed to livestock. Do not contaminate feed, food, water, or food pro-
cessing equipment.
/77000JC Commercial, Institutional and
Industrial Areas (Inedible Areas) The 80 percent soluble concentrate/
/72000JC Eating Establishments (Inedible solid formulation is limited to pro-
Areas)fessional pest control operators.
/71000JC Food Processing. Handling and
Storage Plants/Areas (Inedible
Areas)
IS/.SAAA Ants 0.4-0.8 oz/ Outdoor treatment. Dry bait. Apply
IVAHAAA Crickets 1,000 sq.ft around perimeter of building.
(5% G)
Issued: 3-22-82 111-057901-47
-------
EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l^IYDROXYETH YL)PHOSPHONATE
Site and Pest
Dosages and Tolerance, Use, Limitations
Formulation(s)
Commercial, Institutional and Industrial Areas (Inedible Areas)
(continued)
IVAAABA
Cockroaches
IQAUAFA
House fly
Bait
(1% G)
Indoor treatment. Dry bait. Place
a small quantity on pieces of paper,
cardboard, or in shallow jar lids in
locations Inaccessible to children
and animals. Place where dying in-
sects cannot fall into food, uten-
sils, or drinking water. Wet the
bait slightly for increased killing
efficiency.
Indoor or outdoor treatment. Apply
as a coarse spray or brush onto se-
lected interior and exterior sur-
faces of buildings where pest con-
gregates. Apply only when animals
and humans are absent. Do not allow
reentry until treated surfaces are
dry. Mix spray with 1 pound of su-
gar per gallon for longer residual
control. Repeat at 7 to 14 day in-
tervals as needed.
40 g/8.75 Ib Indoor or outdoor treatment. Apply
sugar where pest congregates. Repeat as
[4 this/ needed.
1,000 sq.ft]
(80% SC/S)
40 g/gal
[1.33 gal/
1,000 sq.ftj
(80Z SC/S)
ISASAVA
0.04 ozl
1,000 sq.ft
(1% G)
Texas harvester ant 0.67-1 cup
5% G/mound
(5% G)
/890030A
IVAAABA
IOAUAFA
Garbage Dumps
Cockroaches
House fly
0.04 ozl
1,000 sq.ft
(1% G)
Outdoor treatment. Dry bait. Scat-
ter on ground where pest congre-
gates.
Broadcast application over mound
surface. Inspect treated mound
regularly and repeat applicaions as
needed.
Dry bait. Scatter directly on gar-
bage dumps where pests breed or con-
gregate.
Issued: 3-22-82
111-057901-48
74
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-IRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Site and Pest Dosages and Tolerance. Use, Limitations
Formulation(s)
Garbage Dumps (continued)
40 g/gal Outdoor treatment. Apply to garbage
[5 gal/ piles. Mix with 1 pound of sugar
1,000 sq.ft] per gallon for longer residual con-
(80Z SC/S) trol. Repeat at 7 to 14 day inter-
vals as needed.
AERIAL. MOTHPROOFING AND TANK MIX APPLICATIONS
9001500 Aerial Application
AAAAAAA
— Refer to
AGRICULTURAL CROPS
All sites except Field Crops, Truck
Crops, Tobacco (to be transplanted)
FOREST. CHAPARRAL. NONAGRICULTURAL AND WASTELANDS
Forest Trees
Issued: 3-22-82 III-057901-49
75
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-IRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Listing of Registered Pesticide Products by Formulation
902 technical chemical
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
011556-00006
971 technical chemical
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
011678-00003 013801-00015 040831-00108
982 technical chemical
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
002749-00181 003125-00009 011556-00030
80% formulation intermediate
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
002749-00103 003125-00066 003125-00129 007173-00104
011678-00010 040831-00107
82% formulation intermediate
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
011556-00055
3% dust
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
001202-00269
5% dust
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
000635-00395 000769-00396 001202-00268 002342-00913
002749-00331 003125-00064 010226-00036 040831-00102
044317-00026
8Z dust
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
040831-00104
0.4% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
002724-00225
0.92% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
009172-00001
1% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (037901)
000239-00778 000270-00057 000327-00095 000869-00146
001386-00281 001990-00491 002217-00557 003125-00007
003125-00151 006762-00052 008590-00170 042057-00077
Issued: 3-22-82 111-057901-50
76
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EPA Index to Pesticide Chemicals
DIMETHYL (2,2,2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Listing of Registered Pesticide Products by Formulation (continued)
3% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
010226-00029
3.5% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
037686-00059
4% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
002393-00437 009779-00187 037686-00058
5% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
000829-00203 002269-00154 002935-00401 003125-00076
003125-00217 005905-00229 006735-00193 007001-00113
008612-00081 037686-00049
6.2% granular
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
002169-00211
5% pelleted/tableted
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
006973-00006
37.8% pelleted/tableted
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
000618-00085
90Z pelleted/tableted
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
000270-00060 000602-00214
37.8% wettable powder/dust
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901) plus
thiabendazole (060101)
000618-00086
1% impregnated materials
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
001663-00014
4 Ib/gal soluble concentrate/liquid
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
003125-00143 003125-00210 006735-00206 006735-00208
040831-00111 042057-00097
6 Ib/gal soluble concentrate/liquid
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (05790])
040831-00106
Issued: 3-22-82 111-057901-51
77
-------
9999999
EPA Index to Pesticide Chemicals
DIMETHYL (2,2, 2-TRICHLORO-l-HYDROXYETHYL)PHOSPHONATE
Listing of Registered Pesticide Products by Formulation (continued)
40.5% soluble concentrate/liquid
dimethyl (2,2, 2-trichloro-l-hydroxyethyl) phosphonate (057901)
002749-00138 008730-00030 045128-00002
50% soluble concentrate/solid
dimethyl (2, 2, 2-trichloro-l-hydroxyethyl) phosphonate (057901)
003125-00049 003125-00089
80% soluble concentrate/solid
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901)
000769-00506 001021-00336 001023-00051 002749-00107
002749-00116 003125-00118 003125-00184 003125-00227
003770-00287 011556-00031 011556-00039 011678-00011
040831-00103
1.5 Ib/gal liquid ready-to-use
dimethyl (2,2,2-trichloro-l-hydroxyethyl) phosphonate (057901) plus
petroleum distillate (063503)
003125-00278
8% liquid ready-to-use
dimethyl (2,2, 2-trichloro-l-hydroxyethyl) phosphonate (057901)
002393-00389 002724-00218 002749-00147 003770-00288
011556-00032
State Label Registrations
AZ Reg. No.
010163-06400 037832-08360
CA Reg. No.
001202-05069
006023-03051
007001-07754
009319-04536
003125-07849
006973-03552
006434-04719
009319-04550
003125-07850
006973-03553
008434-04721
011093-07253
005967-05190
006973-03554
009319-04535
FL Reg. No.
002342-06966
009859-04432
GA Reg. No.
001812-03875
NY Reg. No.
003125-07832
PA Reg. No.
003125-07831
TX Reg. No.
003125-07830
Issued: 3-22-82
002342-06968
014775-08743
038655-10422
003125-07838
035222-07160
009859-03942
111-057901-52
78
-------
II. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
A. This portion of the guidance document is a Notice
issued under the authority of FIFRA Section 3(c)(2)(B)
and describes, in table format, the data required
for maintaining the registrability of each product.
Additionally, a bibliography (Appendix II-l) is
included that identifies that data considered as
part of the data base supporting this standard. EPA
has determined that additional generic data described
in this Notice must be submitted to EPA for evaluation
in order to maintain in effect the registration(s)
of your product(s) identified as an attachment to
the cover letter accompanying this guidance document.
As required by FIFRA Section 3(c)(2)(B), you are
required to take appropriate steps to comply with
this Notice.
EPA may suspend the registration of each of those products
unless, within the specified time, you have informed F,PA
how you will satisfy the requirements of this Notice.
Any such suspension will remain in effect until you have
complied with the terms of this Notice.
B. What Generic Data I/ Must Be Submitted. You may ascertain
which generic data you must submit by consulting Table A
at the end of this chapter. That table shows all the
generic data needed to evaluate the continued registrability
of all products, and the dates by which the data must be
submitted. The required data must be submitted and any
necessary studies must be conducted in accordance with
EPA-approved protocols, the Pesticide Registration
Guidelines 2_/', or data collected under the approved
protocols of the Organization for Economic Cooperation
and Development (OECD). If you wish not to develop data
which are necessary to support the registration or
reregistration of certain uses appearing in your labeling,
you may delete those uses at the time you submit your
revised labeling.
Also for certain kinds of testing (generally ecological
effects), EPA requires the test substance to be a "typical
formulation," and in those cases EPA needs data of that
I/ Generic data pertain to the properties or effects of a
particular ingredient, and thus are relevant to an evaluation of
the risks of all products containing that ingredient (or all such
products having a certain use pattern), regardless of a.iy such
product's unique composition or use. Procuct-specific data relate
only to the properties or effects of a prodi.ct with a particular
composition (or a group of products with closely similar composition)
2/ The Pesticide Registration Guidelines were reproposed on
November 24, 1982 in 47 Federal Register 53192.
79
-------
type for each major formulation category (e.g., emulsifiahle
concentrates, wettable powders, granulars, etc.) These
are classified as generic data and when needed are
specified in Table A. EPA may possess data on certain
"typical formulations" but not others. Note; The "typical
formulation" data should not be confused with product-
specific data (Table B) which are required on each
formulation. Product-specific data are further explained
in Chapter IV of this document.
C. Options Available for Complying With Requirements
to Submit Data
Within 90 days of your receipt of this Notice you must
submit to EPA a completed copy of the form entitled "FIFRA
Section 3(c)(2)(B) Summary Sheet" [EPA Form 8580-1, Appendix
11-2} for each of your products. On that form you must
state which of the following methods you will use to comply
with the requirements of this Notice:
1. (a) Notify EPA that you will submit the data, and
(b) either submit the existing data you believe
will satisfy the requirement, or state that
you will generate the data by conducting
testing. If the test procedures you will
use deviate from (or are not specified in)
the Registration Guidelines or protocols
contained in the Reports of Expert Groups
to the Chemicals Group, Organization for
Economic Cooperation and Development (OECD)
Chemicals Testing Programme, you must enclose
the protocols you will use.
2. Notify EPA that you have entered into an agreement
with one or more other registrants to jointly
develop (or share in the cost of developing) the
data. If you elect this option, you must notify EPA
which registrants) are parties to the agreement.
3. File with EPA a completed "Certification of Attempt to
Enter Into an Agreement With Other Registrants for
Development of Data" (EPA Form 8580-6, Appendix II-3)_V
4. Request that EPA amend your registration by deleting the
uses for which the data are needed. (This option is not
available to applicants for new products.)
V FIFRA Section 3(c)(2)(B) authorizes joint development of
data by two or more registrants, and provides a mechanism by
which parties can obtain an arbitrator's decision if they agree
to jointly develop data but fail to agree on all the terms of
the agreement. The statute does not compel any registrant to
agree to develop data jointly.
(Footnote continued at bottom of next page)
80
-------
5. Request voluntary cancellation of the registrationfs)
of your products for which the data are needed. (This
option is not available to applicants for new products.)
D. Procedures for Requesting Changes in Testing Methodology
and Extensions of Time
EPA recognizes that you may disagree with our conclusions
regarding the appropriate ways to develop the required
data or how quickly the data must be submitted. If the
test procedures you plan to use deviate from (or are not
specified in) the registration guidelines or protocols
contained in the reports of the Expert Groups to the
Chemical Groups, Organization for Economic Cooperation
and Development (OECD) Chemicals Testing Programme, you
must submit the protocol for Agency review prior to the
initiation of the test.
If you think that you will need more time to generate the
required data than is allowed by EPA's schedule, you may
submit a request for an extension of time. The extension
request must be submitted in writing to the Product
Manager. The extension request should state the reasons
why you conclude that an extension is appropriate. While
EPA considers your request, you must strive to meet the
deadline for submitting the required data.
(Footnote continued from previous page)
In EPA's opinion, joint data development by all registrants
who are subject to the requirements to submit a pertinent item
of data or a cost-sharing agreement among all such registrants
is clearly in the public interest. Duplication of testing could
increase costs, tie up testing facilities, and subject an unneces-
sarily large number of animals to testing.
As noted earlier, EPA has discretion not to suspend the
registration of a product when a registrant fails to submit data
required under FIFRA Section 3(c)(2)(B). EPA has concluded that
it is appropriate to exercise its discretion not to suspend in
ways which will discourage duplicative testing. Accordingly, if
(1) a registrant has informed us of his intent to develop and
submit data required by this Notice; and (2) a second regis-
trant informs EPA that it has made a bona fide offer to the
first registrant to share in the expenses of the testing [on
terms to be agreed upon or determined by arbitration under FIFRA
Section 3 ( c) ( 2 ) (B) ( iii ) ] ; and (3) tl
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORFON
§158.120 - PRODUCT CHEMISTRY
Guideline Citation and Test
Name of Test Substance V
PRODUCT IDENTITY:
61-1 - Identity of Ingredients
61—2 SLciLwiKitinL o£ CurtiposiLioti
61-3 - Discussion of Formation of
Ingredients
Analysis and Certification of Product
Ingredients
62 1 Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Methods for
Enforcement of Limits
Physical and Chemical Characteristics
63-3 - Physical State
63-4 - Odor
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
Guidelines Are Data Footnote
Status Required 2/ Number
Yes No
R ffl
R/Y /
/A/
R XV
CR A7
R A7
R A7
R A/
R/Y/
/A/
R /V
n
n
n
n
n
n
n
n
n
82
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
§158.120 - PRODUCT CHEMISTRY (Con't)
Guideline Citation and
Name of Test
Test
Substance I/
Guidelines Are Data Footnote
Status Required 2/ Number
Yes No
Physical and Chemical Characteristics
(Continued)
DO D rieiting foint
DJ o aoiiing roint
63-7 - Density, Bulk Density, or
Specific Gravity
63-8 - Solubility 1
63-9 - Vapor Pressure
DJ lu Dissociation constant
63-11 - Octanol/water partition
coefficient
63-12 - pH
63-13 - Stability
63-20 - Corrosion Characteristics
Other Requirements:
64-1 - Submittal of samples
TGAI
TGAI
TGAI
DGAI or PAI
PAI
PAI
PAI
TGAI
TGAI
TGAI
Choice
DATA REQUIREMENT FOOTNOTES:
V Composition: TGAI=Technical Grade of the Active
2/ Data must be submitted no later than December,
R
R
R
R
R
R
R
R
R
R
CR
Ingredient;
1984.
A/
A/
A7
A/
A7
A/
/v
A7
n
PAI=Pure
.—j
A7 3/
n
n
n
n
n
n
n
n
A7
Active Ingredient
3/ Not required because the technical material is a solid at room temperature.
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirements
Composition
Does EPA Have Data
To Satisfy This
V Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.125 Residue Chemistry
171-4 - Nature of Residue (Metabolism)
- Plants
- Livestock
PAIRA
PAIRA and plant
metabolites
Partial
Partial
00005296
00005300
00091787
00005297
Yes3/
Yes4/
171-4 - Residues Analytical Method
- Plant residues
- Animal residues
171-4 - Storage Stability Data
TGAI and meta-
bolites
TGAI and meta-
bolites
PAI
Yes
Yes
Yes
GS0104038
GS0104005
GS0104007
GS0104041
GS0104060
GS0104001
GS0104002
GS0104006
GS0104056
GS0104057
GS0104008
GS0104061
No
No
No
84
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirements
Composition
Does EPA Have Data
To Satisfy This
V Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.125 Residue Chemistry
(continued)
171-4 - Magnitude of the Residue-
Residue Studies for Each
Food UseV
- Root and Tuber Vegetables Group
0 Rutabagas TEP
0 Beets TEP
0 Radishes TEP.
0 Carrots TEP
0 Sugar Beets TEP
0 Turnips TEP
- Leaves of Root and Tuber Vegetables Group
0 Beet Tops TEP
0 Sugar Beet Tops TEP
- Bulb Vegetables Group
0 Garlic TEP
0 Onions TEP
- Leafy Vegetables (Except Brassica Vegetables) Group
0 Spinach TEP
0 Lettuce TEP
0 Celery TEP
No
Yes
No
Partial
No
No
Yes
No
No
No
No
Partial
No
GS0104009
GS0104010
GS0104009
GS0104011
Yes6/
No
Yes6/
Yes?/
Yes8/
Yes6/
Yes6/
Yes6/
Yes6/
85
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirements
Composition
Does EPA Have Data
To Satisfy This
V Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
TEP
TEP
TEP
TEP
TEP
TEP
158.125 Residue Chemistry
(continued)
171-4 - Magnitude of the Residue-
Residue Studies (continued)
- Brassica Leafy Vegetables Group
0 Brussels Sprouts
0 Broccoli
0 Cabbage
0 Kale
0 Cauliflower
0 Collards
- Legume Vegetables (Succulent or Dried) Group
0 Cowpeas (succulent and dried) TEP
0 Dried Beans TEP
0 Lima Beans TEP
0 Snap Beans TEP
- Foliage of Legume Vegetables Group
0 Bean Vines TEP
0 Cowpea Vines TEP
0 Lima Bean Vines and Hay TEP
No
No
No
No
Partial
No
Partial
Partial
Partial
Partial
No
Partial
Partial
GS0104012
GS0104013
GS0104003
GS0104014
GS0104062
GS0104015
GS0104013
GS0104014
GS0104063
YesV
YesW
Yes20/
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORTON
Data Requirements
Composition
Does EPA Have Data
To Satisfy This
V Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.125 Residue Chemistry
(continued)
171-4 - Magnitude of the Residue-
Residue Studies (continued)
- Fruiting Vegetables (Except Cucurbits) Groups
0 Peppers TEP
0 Tomatoes TEP
- Fruiting Vegetables Curcubits Group
0 Pumpkins TEP
0 Watermelon TEP
- Citrus Fruits Groups
0 Citrus Fruits TEP
- Small Fruits and Berries Group
0 Blueberries TEP
0 Strawberries TEP
- Cereal Grains Group
0 Barley • TEP
0 Corn TEP
Oats
Wheat
TEP
TEP
Partial
Partial
Partial
No
Partial
Yes
No
Partial
Yes
Partial
Partial
GS0104016
GS0104017
GS0104018
GS0104064
GS0104067
GS0104019
GS0104043
GS0104020
GS0104021
GS0104022
Yes£f/
No
Yes£/
No
Yes27/
Yes28/
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORF3N
Data Requirements
Composition
Does EPA Have Data
To Satisfy This
V Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
158.125 Residue Chemistry
(continued)
171-4 - Magnitude of the Residue-
Residue Studies (continued)
- Forage, Fodder, and Straw of Cereal Grains Group
0 Barley Forage and Straw TEP
Corn Forage and Fodder
Oat Forage and Straw
TEP
TEP
Partial
Yes
Partial
Partial
0 Wheat Forage and Straw TEP
Grass Forage, Fodder, and Hay Group
0 Pasture Grasses (forage and hay) TEP Partial
0 Rangeland Grasses (Forage and Hay) TEP Partial
Non-Grass Animal Feeds (Forage, Fodder, Straw, and Hay) Group
0 Alfalfa Forage and Hay TEP Partial
Birdsfoot Trefoil Hay
Clover Forage and Hay
TEP
TEP
Partial
Partial
GS0104044
GS0104023
GS0104045
GS0104024
GS0104046
GS0104025
GS0104047
GS0104026
GS0104048
GS0104049
GS0104050
GS0104027
GS0104068
GS0104051
GS0104052
GS0104028
GS0104053
GS0104054
Yes£9_/
No
Yes30/
Yes31/
Yes32/
Yes33/
Yes^4/
Yes35/
88
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirements
158.125 Residue Chemistry
(continued)
171-4 - Magnitude of the Residue-
Residue Studies (continued)
- Miscellaneous Crops
0 Artichokes
0 Bananas
0 Cottonseed
0 Flax
0 Peanuts
0 Saf flower Seed
0 Tobacco
- Food Producing Animals
0 Cattle (Fat, meat and
meat byproducts)
0 Goats, Horses, and Sheep
0 Milk
V
Composition
TEP
TEP
TEP
TEP
TEP
TEP
TEP
EP, TGAI or
Plant Metabolites
EP, TGAI or
Plant Metabolites
EP, TGAI or
Plant Metabolites
Does EPA Have Data
To Satisfy This
Requ irement ? ( Yes ,
No or Partially)
No
Yes
No
Partial
Yes
Partial
No
Partial
Yes
Partial
Bibliographic
Citation
-
GS0104040
-
GS0104030
GS0104058
GS0104031
-
GS0104032
GS0104033
GS0104034
GS0104035
GS0104036
GS0104065
GS0104066
GS0104037
GS0104038
GS0104055
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?2/
Yes37/
NO
Yes^V
OQ /
^Jf^fiJ _7 /
No
YesfV
Yesf/
Yes42/
No
YesfV
Poultry and Eggs
EP, TGAI or
Plant Metabolites
Partial
GS0104004
Yes44/
PQ
-------
TABLE A
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
_!/ Composition: TGAI = Technical grade of the active ingredient; PAIRA =
Pure active ingredient, radiolabelled; TEP = Typical end-use product;
EP = End-use product.
2/ Data must be submitted no later than June . 1 987 .
3/ The following additional data are required:
o Studies demonstrating the degree of absorption of trichlorfon by
both leaves and roots of representative crops as well as the subsequent
translocation and metabolism of trichlorfon and/or its metabolites.
[14c]Trichlorfon must be used for these studies. An attempt must
be made to identify all metabolites including volatile, toxic
compounds (which may include DDVP). If additional metabolites of
concern are indicated, additional methodology and residues studies
for the r.a.c.s may be required.
_4/ The following studies are required to adequately define the animal
metabolism of trichlorfon:
o Metabolism studies utilizing both poultry and ruminants. Animals
must be orally dosed with [^-^C]trichlorfon and the identity and
distribution of residues in tissues, milk, and eggs, where appropriate,
must be detemined. If, however, the ruminant study indicates that
no additional metabolites of concern exist then the poultry study
may be waived.
o In addition, a metabolism study with C1^]trichlorfon should be
performed reflecting the use of the high-pressure dermal spray
application of the 80% SC/S at 8 Ib. a.i./A gallon. Meat and milk
samples must be analyzed for the identity and distribution of
possible residues of concern.
o If additional residues of concern besides the parent compound
trichlorfon per se are found, additional methodology and residue
data for meat and milk may have to be submitted.
5/ Dust formulations are manufactured in low volumes and are rarely applied
to crops. Therefore, data are not required for dust formulations unless
there is an indication that dust is frequently used on a given crop.
6/ There are currently no federally registered products for this use.
7/ The available data do not support the established tolerance for carrots.
Residue data were submitted only for SC/S applications. These residue
values were below the tolerance; however, geographic representation was
inadequate. The following additional data are required:
90
-------
TABLE A
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o Foliar treatments (aerial and ground) at geographically representative
field sites with either one of the SC/L or one of the SC/S formulations
at 1.5 Ib ai/A and subsequent residue analyses which reflect the
maximum registered use pattern. Field site data must include arid
regions in California; alternatively, a label restriction against
usage on irrigated carrots may be proposed.
o The registrant must submit information specifying the method of
application used in the tests reviewed in this section of the
trichlorfon Standard.
8/ No valid data are available to support the sugar beet tolerance; all
residue data submitted were generated with an invalid cholinesterase
inhibition technique. The following data are required:
o Foliar treatments with one of the SC/L or SC/S formulations at 1.5
Ib ai/A and subsequent residue analyses on roots which reflect the
maximum current use pattern.
o Residue data for processed sugar beet products (molasses, dehydrated
pulp, and refined sugar) if residues are detected in the raw agricul-
tural commodity.
9/ Based on the available data, a tolerance of 0.1 ppm (negligible) should
be established for trichlorfon residues in or on table beet tops. No
Codex MRL or Canadian or Mexican tolerance exists for trichlorfon resi-
dues in or on beet tops. The existing label directions are considered
to be adequate except that the restriction against using beet tops as
food must be deleted.
10/ The available residue data are not sufficient to support the established
tolerance for lettuce. Only the 50% SC/S formulation was tested? resi-
dues were below the tolerance except in the case of the trial conducted
in CA, the principal growing region. Several pertinent aspects were un-
specified: whether or not data for head lettuce represent heads with or
without wrapper leaves, the application method (aerial or ground), and
whether or not field sites in CA and AZ were irrigated. Additional data
are required which reflect:
o Field trials in CA or AZ (irrigated and non-irrigated plots of head
and leaf lettuce) and in CO and NY with one of the SC/S formulations
at 1 Ib ai/A. Soil and foliar applications must be made at three or
more weekly intervals with ground and aerial equipment. Sampling
(with and without wrapper leaves) should reflect the maximum current
use pattern.
91
-------
TABLE A
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o Head and leaf lettuce field trials in CA or AZ (irrigated and non-
irrigated plots) and CD and NY with one of the G formulations at 1.5
Ib ai/A. Applications (over the row and around the plant base) must
be made at three or more weekly intervals with ground and aerial
equipment. Sampling (with and without wrapper leaves) should reflect
the current maximum application rate and use.
ll/ There are no valid data to support the established tolerance for
residues resulting from the maximum registered rate for brussels
sprouts because the analytical method used to detect trichlorfon
residues is invalid. The following residue data are required:
o Field trials from sites in CA, TX, and AZ using one of the SC/S
formulations or the 6 Ib/gal SC/L formulation at 1 Ib ai/A. Soil
and foliar applications must be made at three or more weekly
intervals with ground and aerial equipment. Sampling should reflect
the maximum current use pattern.
12/ There are no valid data to support the established tolerance for resi-
dues resulting from the maximum registered rate for cabbage because the
colorimetric method used detected the degradation products of trichlor-
fon rather than the parent compound. Further, the analytical method
(a cholinesterase inhibition technique) used to detect trichlorfon
residues is not valid. The following data are required:
o Field trials from sites in FL, TX, NC, NJ, and CA using the 6 Ib/gal
SC/L or one of the SC/S formulations at 1 Ib ai/A, and one of the G
(bait) formulations at 1 Ib ai/A. Soil (G only) and foliar
applications must be made at three or more weekly intervals with
ground and aerial equipment. Sampling (with and without wrapper
leaves) should reflect the maximum current use pattern.
13/ The available data do not support the established tolerance for residues
in or on cauliflower resulting from the maximum registered rate. Only
the 5% D formulation was tested at a single Canadian site and the appli-
cation method (ground or aerial) was unspecified. Other data were
obtained with an invalid analytical method (a cholinesterase inhibition
technique) used to detect trichlorfon residues. The following data
are required:
o Field trials from sites in CA, AZ, NY, and MI using one of the SC/S
formulations or the 6 Ib/gal SC/L formulation at 1 Ib ai/A and one
of the G (bait) formulations at 1 Ib ai/A. Soil (G only) and foliar
applications must be made at three or more weekly intervals with
ground and aerial equipment. Sampling should reflect the maximum
current use pattern.
92
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TABLE A
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
14/ There are no valid data to support the established tolerance for
trichlorfon residues in or on collards resulting from the maximum
registered rate because the analytical method (a cholinesterase
inhibition technique) used to detect trichlorfon residues is not valid.
The following data are required.
o Field trials from two or more Gulf Coast localities using one of the
SC/S formulations or the 6 Ib/gal SC/L formulation at 1 Ib ai/A and
one of the G (bait) formulations at 1.5 Ib ai/A. Soil and foliar
applications must be made at three or more weekly intervals with
ground and aerial equipment. Sampling should reflect the maximum
use pattern.
15/ The available data do not support the established tolerance for cowpeas;
however, residue data submitted for the SC/S formulation were below
the tolerance. Only one dried bean sample was submitted. The follow-
ing additional data are required:
o Soil applications with one of the G formulations (bait) at 1 Ib
ai/A and subsequent residue analyses on cowpeas, which reflect the
maximum current use pattern. Data on dried seed must also be
provided.
16/ The available data do not support the established tolerance for residues
of trichlorfon in or on dried beans. However, residues in or on dried
soybeans grown in north central and southern states and Ontario were
<0.02 ppm >14 days after the last of four applications of the 80% SC/S
or 4 Ib/gal SC/L formulations at <1.5 Ib ai/A; these data satisfy the
dried bean data requirements for SC/S and SC/L applications at all
geographic locations except CA, CO, and WA. The following additional
data are required:
o Foliar applications with one of the SC/S or SC/L formulations and
soil applications with one of the G formulations (bait) at 1.5 Ib
ai/A and subsequent residue analyses on dried beans which reflect
the maximum current use pattern. Full geographic representation is
required for G applications; SC/S or SC/L field trial data ar
eneeded only for CA, CO, and WA.
IT/ The available data do not support the established tolerance for lima
beans; however, data submitted for SC/S and SC/L applications were
below the tolerance. The following additional data are required:
o Broadcast soil applications with one o^ the G formulations (bait)
at 1.5 Ib ai/A and subsequent residue analyses on beans (shelled)
and beans in pods at intervals which reflect the maximum current
use pattern.
93
-------
TABLE A
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
18/ The available data do not support the established tolerance for snap
beans. Residue trials were conducted only with the SC/S formulation;
the test submitted from Wisconsin contained residue-exceeding values.
Also, geographic representation was inadequate. The following additional
data are required:
o Foliar applications with one of the SC/L fornulations and soil
applications with one of the G formulations (bait) at 1.5 Ib ai/A
and subsequent residue analyses on beans at intervals which reflect
the maximum current use pattern. Test locations must include FL
and GA.
19/ There are no data to support the established tolerance for bean vines.
The following data are required:
o Residue dissipation studies following foliar applications with one
of the SC/L or SC/S formulations at 1.5 Ib ai/A; this is necessary
to establish a pregrazing interval as well as to support the
tolerance for bean vines.
o Foliar applications with one of the SC/L or SC/S formulations at 1.5
Ib ai/A and subsequent residue analyses on succulent and dried
vines (vine hay) harvested 14 days after the last treatment.
20/ The available data do not support the established tolerance for cowpea
vines. Residue data were subitted only for the SC/S formulation; these
residue values were below the tolerance. No data for residues in or
on vine hay were submitted. The following additional data are required:
o Residue dissipation studies following foliar applications with one
of the SC/L formulations at 1.5 Ib ai/A; and soil application with one
of the G formulations (bait) at 1 Ib ai/A; this is necessary to estab-
lish a pregrazing interval for cowpea vines.
o Foliar applications with one of the SC/L or SC/S formulations at 1.5
Ib ai/A and soil applications with one of the G formulations (bait) at
1 Ib ai/a and subsequent residue analyses on succulent (SC/L and G
formulations only) and dried vine (vine hay) harvested 14 days
after the last treatment application.
21/ The available data do not support the established tolerance for lima bean
vines and hay; however, data submitted for SC/S and SC/L applications were
below the tolerance.
There are no available data to support the established tolerance for lima
bean vine hay. The following additional data are required:
94
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o Residue dissipation studies following two soil applications with one
of the G formulations (bait) at 1.5 Ib ai/A; this is necessary to estab-
lish a pregrazing interval for lima bean vines following G applications.
o Foliar applications with one of the SC/L or SC/S formulations and
soil applications with one of the G formulations at 1.5 Ib ai/A and
subsequent residue analyses on succulent (G formulations only) and
dried vines (vine hay) harvested 3 (SC/S), 14 (SC/L), and 30 (G) days
after the last treatment application.
22/ The available data do not support the established pepper tolerance follow-
ing use of the registered formulations at their maximum application rates.
Only the 50% SC/S and 5% D formulations were tested and the application
method (aerial or ground) was unspecified for both formulations. Additional
data are required which reflect:
o Field trials from sites in FL, CA, NJ, NC and TX using one of the
formulations at 1 Ib ai/A. Soil (over the row and around plant bases)
and foliar applications must be made at three or more weekly intervals
with ground and aerial equipment. Sampling should reflect the maximum
current use pattern.
23/ The available data do not support the established tomato tolerance fol-
lowing use of the registered formulations at their maximum application
rates. Residues were below the tolerance; however, only the 5% D and
50% SC/S formulations were tested, the application method (aerial or
ground) was unspecified, the prinicpal growing regions of the crop were
not represented, and cooked samples were analyzed with an invalid method
(see Report No. 2412 for description of the cholinesterase inhibition
technique). Additional data are required which reflect:
o Residue analysis of cooked tomatoes (washed and unwashed) following
multiple (three or more) foliar or direct applicatons with one of
the D formulations at 1.25 Ib ai/A. The final treatment should be
made on the day of sampling.
o Field trials from sites in FL and TX using an SC/S formulation at 1
Ib ai/A. Foliar applications must be made at three or more weekly
intervals with ground and aerial equipment. Sampling should reflect
the maximum current use pattern.
o Field trials from sites in FL, SC, TX, AR, CA and NJ using one of the
G formulations at 1 Ib ai/A for multiple (three or more weekly inter-
vals) soil and foliar applications, respectively, with grouna and
aerial equipment. Sampling should reflect the maximum current use
pattern.
95
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o If residues are found in the tomato fruit, then a processing study
is required to determine residues in pomace (wet and dry), puree,
catsup and juice.
24/ The available data do not support the established tolerance for pumpkins;
however, data are sufficient for SC/S applications. The following addi-
tional data are required:
o Single soil applications (made 14 days prior to harvest) of one of
the G formulations at 1 Ib ai/A using aerial and ground equipment.
Sufficient data are not available to assess the adequacy of the
tolerance covering residues resulting from the maximum registered rate
or the label directions. No Canadian or Mexican tolerances exist for
residues of trichlorfon in or on pumpkins. The Codex MRL and U.S.
tolerance are identical.
25/ The available data do not support the established tolerance for citrus
fruit. Since aerial applications can be made using spray volumes as low
as 1 gallon/A, aerial ULV data are necessary reflecting that particular
use. The following additional data are required:
o Single aerial ULV applicatiosn followed by two ground applications
of one of the SC/S formulations at 4 Ib ai/A and subsequent residue
analyses on unwashed whole fruit at intervals which reflect the
maximum current use pattern. .Data should be submitted for oranges,
lemons, and grapefruit.
o Processing studies on oranges treated according to the application
regime outlined above to determine residue in or on wet and dried
pulp, oil, peel, juice, and molasses.
26/ The available data do not support the established tolerance for trichlorfon
residues in or on barley grain which may result from use of the registered
formulations in accordance with the label directions. Only 50% SC/S formu-
lation was tested; residues were below the tolerance, but only one application
was made (up to three per season are permitted). The method of application
(ground or aerial) was unspecified. Additional residue data are required
which reflect the following:
o Multiple (> 3 weekly intervals) foliar aerial applications of one
of the SC/L or one of the SC/S formulations at 1 Ib ai/A.
o If residues occur in grain, then the fractionation study required for
wheat will be sufficient to determine residues in barley germ and
milled products.
96
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)"
27/ The available data do not support the established tolerance for oat
grain for the following reasons: only a single application of the
50% SC/L was made (up to three treatments per season are permitted);
the application method (aerial or ground) was unspecified; and the
tolerance-exceeding residues found in the CA test site cannot be con-
sidered anomalous from the limited number of tests provided. Additional
data are required which reflect the following:
o Field trials conducted in NB and OH or NY which include multiple
(three or more weekly intervals) foliar, aerial applications of one
of the SC/L or SC/S formulations at 1 Ib ai/A.
o If residues occur in grain, then the fractionation study required
for wheat will be sufficient to determine residues in milled
products.
28/ The available data do not support the established tolerance for wheat
grain for the following reasons: only a single application of the
50% SC/L was made (up to three treatments per season are permitted);
the application method (aerial or ground) was unspecified; and the
tests were not conducted in the principle wheat growing regions.
Additional data are required which reflect the following:
o Field trials conducted in KS, TX or OK, IL or IN, and MT which include
multiple (three or more weekly intervals) foliar, aerial applications
of one of the SC/L or SC/S formulations at 1 Ib ai/A.
o If residues occur in grain, then a fractionation study is required
to determine residues in milled products and by-products.
29/ The available data do not support the established tolerance for residues
in or on barley straw which may result from use of the registered formu-
lations at the maxittum application rate since only green samples were
collected on the day of treatment. The available data do support the
established tolerance for barley forage. The following additional
residue data are required:
o Multiple (more than three weekly intervals) foliar, aerial treatments
with one of the SC/L formulation or one of the SC/S formulations at
1 Ib ai/A. This is necessary to support the straw tolerance and to
establish a prefeeding interval.
30/ The available residue data do not support the established tolerance for
straw since only green samples were collected at zero and 3 days after
treatment. The available data do support the established tolerance
for oat forage. The following additional residue data are required:
97
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o Multiple (three or more weekly intervals) foliar, aerial treatments
with one of the SC/k formulation or one of the SC/fe formulations at
1 Ib aiA- This is necessary to support the straw tolerance and to
establish a prefeeding interval.
31/ The available residue data do not support the established tolerance for
straw since only green samples were collected on the day of treatment.
The available data do support the established tolerance for forage.
Additional residue data are required which reflect the following:
o Multiple (more than three weekly intervals) foliar, aerial treatments
with one of the SC/L formulations or one of the SC/fe formulations at
1 Ib aiA- This is necessary to support the forage and fodder toler-
ances and to establish a prefeeding interval.
32 / The available residue data do not support the established tolerances for
trichlorfon residues in or on pasture grasses and hay following use of the
registered formulations at their maximum registered rates. The following
additional data are required:
o Aerial and ground ULV foliar applications of the 4 Ib/gal SC/L at 1
Ib ai/A followed by a second treatment at 0.5 Ib ai/A- Data should
be collected for forage and hay on the day of the second application.
o Sufficient data are available for dilute foliar applications of the
4 Ib/gal SC/L or the 80% SC/fe formulations; however, the registrant
must specify the method of application.
33 / The available data do not support the established tolerances for
trichlorfon residues in or rangeland grass forage and hay following
use of the registered formulations at their maximum use rates. The
following additional data are required:
o Residue data are required for two aerial ULV applications of the
1.5 Ib/gal RTU formulation at OA Ib ai/A- Replicate forage and
hay samples should be collected on the day of the final treatment.
o Data are required reflecting single aerial and ground applications
of either the 50 or 80% SC/S. Replicate forage and hay samples
must be analyzed.
o The available residue data for ULV applications of the 4 Ib/gal
SC/L formulation are inconsistent and additional data are needed.
This must include replicate forage and hay samples following two
aerial or ground treatments, the first at 1 Ib/aiA and the second
at 0.5 Ib aiA-
98
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
34 / The available data do not support the established tolerance for
alfalfa and alfalfa hay following use of the registered formulations
at their maximum registered rates; all registered formulation classes
were not tested. Residues were below the tolerances for the 50 and
80% SC/S and the 4 Ib/gal SC^ (including ULV treatments). The
following additional data are required:
o Single broadcast soil applications with the 5% P/T or one of the G
formulations at 1 Ib ai/& using ground equipment. Sampling of both
green and dried (hay) alfalfa should reflect the maximum current
use pattern.
35/ Data submitted in support of the tolerance for alfalfa hay were
translated to, and support the established tolerance for, trichlorfon
residues in or on birdsfoot trefoil hay for the following reasons:
o The growth characteristics and use patterns for birdsfoot trefoil
are very similar to those of alfalfa.
o Translated data submitted in support of the established tolerance
for alfalfa hay were adequate for the SC/6 and SC/L formulations.
o Residue levels of trichlorfon in or on birdsfoot trefoil hay are
not anticipated to exceed the maximum levels found in or on alfalfa
hay.
36/ The alfalfa data do not support the established tolerances for clover
and clover hay because all the registered formulation classes were
not tested. Residues resulting from the use of the 50% SC/S and the
4 Ib/gal SC/L formulations were found not to exceed the established
tolerances. The following additional residue data are required:
o Residue studies reflecting single broadcast soil applications
with the 5% P/T formulation at 1 Ib ai/& using aerial equipment.
Sampling of both green and dried (hay) clover shold reflect the
maximum current use pattern.
37/ Insufficient data exist to support the established tolerance for
trichlorfon residues in or on artichokes. The available data were
obtained using an invalid analytical procedure (acetylcholinesterase
inhibition) and additional residue data must be generated using a
valid procedure:
o Ground applications of a dust (D) and, to support Section 24(c)
uses, a granular (G) formulation at 2.5 Ib aiA-
99
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
38/ The available data do not support the established 0.1 ppm tolerance
for trichlorfon residues in or on cottonseed; all of the residue data
submitted were generated using an invalid cholinesterase inhibition
technique. The following data are required:
o Foliar ULV treatments with the 4 Ib/gal SC/L at 0.5 Ib aiAi foliar
treatments with one of the SC/fe or SC/L formulations at 1.5 Ib aiA»
and soil treatments with one of the G formulations (bait) at 1.5 Ib
aiA- All formulations must be applied twice using aerial (SC/L or
SC/fe) or ground (G) equipment; residues should be determined on
both forage (since grazing is permitted) and seed at intervals
which reflect the maximum current use pattern
o If residues are detected in the cottonseed, a fractionation study
to determine residues in the following processed products is
required: meal, hulls, soapstock, crude oil, and refined oil.
39 / The available data do not support the established tolerance for
flaxseed. Residues resulting from the maximum registered application
rate were below the tolerance for flaxseed; however, only the 50% SC/S
was tested, the method of application was unspecified and only single
applications were made (three/season are permitted). The available
data do not support the established 1 ppm tolerance for flax straw
because straw was not analyzed. The following additional data are
required:
o Residue data for flax straw following multiple (no less than three)
applications of the 50 or 80% SC/3 formulation at 1 Ib aiA using
ground and aerial equipment.
o Field trials in MN, TX, and Manitoba,' Canada, with one of the G
formulations at 1 Ib aiA« Soil and foliar applications must be
made at three or more weekly intervals with ground and aerial
equipment.
Sampling of flaxseed should reflect the maximum current use pattern.
Straw should be sampled after drying (for SC/L only).
o If residues are found in flax grain, then the fractionation study
requested for cottonseed will be sufficient to determine residues
in meal (linseed) and hulls.
40 / The available data do not support the established tolerance for
safflower seed. Data were submitted only for the 50% SC/3 formulation
applied at 2 Ib aiA; the method of application was not specified.
Also, of the four residue values submitted, one exceeded the tolerance
by 0.5 ppm. The processing study which was submitted for meal and
100
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
crude and refined oil was unsuitable; safflower seed did not contain
field-treated detectable residues. The following additional data are
required:
o Two applications (at 14 days prior to bloom and at bloom) of one of
the SC^ formulations (foliar applications) at 1.5 Ib ai/A using
aerial and ground equipment, and one of the G (bait) formulations
at 1.5 Ib aiA using ground equipment. Field test locations should
include irrigated regions; alternatively, a label restriction
against usage on irrigated crops may be proposed.
o If residues are found in safflower seed, the processing study
requested for cottonseed will be adequate to determine residues in
meal and oil; if residues in excess of those established for the
r.a.c. are found in meal or oil, food /feed additive tolerances must
be proposed.
41 / The following data are required to assess the exposure of man to
residues of trichlorfon in or on tobacco:
o Residue analyses on green tobacco harvested 3 days after the second
of two foliar applications of the 4% G at 0.6 Ib aiA and one of
the SC/5 formulations at 1 Ib ai/A-
o Residue analyses on green tobacco 3 days after the last of two soil
applications of one of the G (bait) formulations at 1 Ib ai/A? the
second application should be made when plants are approximately 2
ft. tall.
o If residues in green tobacco are >0.1 ppm, pyrolysis products of
trichlorfon must be characterized.
42 / The available data do not support the established tolerance for
trichlorfon in cattle meat, fat, and meat by-products. Although the
feeding studies and pour-on application data are adequate; the following
additional data are required:
o A single high pressure spray application of the 80% SC/5 formulation
(8 Ib aiAOO gal) and residue analyses on meat, fat, and meat by-
products after a posttreatment interval of 14 days.
43 / The available data do not support the established tolerance for
trichlorfon in milk. The feeding studies are adequate; however, the
following additional datPi are required to reflect the dermal use.
101
-------
Generic Data Requirements for Trichlorfon
§158.125 Residue Chemistry
(continued)
o A single pour-on application of the 8% KIU formulation (0.5 fl.
oz/100 Ib body weight but no more than 4 fl. oz/animal) and residue
analyses on milk samples taken twice daily for 7 days following
application or until residues are <0.01 ppm.
44/ The available data indicate that there is no reasonable expectation of
finite residues in eggs; therefore, no tolerance for trichlorfon
residues in or on eggs will be required [40 CFR 180.6a(3)]. However,
no data were submitted pertaining to residues of trichlorfon in or on
poultry meat (muscle, liver, kidney, and fat) resulting from ingestion
of trichlorfon residues at the maximum expected dietary intake level;
therefore, the following additional data are required:
o Poultry feeding studies at 5, 15, and 50 ppm for 28 consecutive
days and subsequent residue analyses on poultry meat (muscle, liver,
kidney, and fat) from animals slaughtered within 24 hours of the
final feeding. If the requested metabolism data reveal no additional
residues of concern and if the requested ruminant residue studies
indicate that residues are nondetectable, then the above poultry
feeding studies will be waived.
45/ No valid data are available to support the tolerance for sugar beet
tops; all residue data submitted were generated with an invalid
cholinesterase inhibition technique. The following data are required:
o Foliar treatments with one of the SC/L or SC/S formulations at 1.5
Ib/A and subsequent residue analysis on tops which reflect the
maximum current use pattern.
102
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TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORPON
Data Requirement
§158.130 Environmental Fate
DEGRADATION STUDIES-LAB:
161-1 - Hydrolysis
Photodegradat ion
161-2 - In water
161-3 - On soil
161-4 - In Air
METABOLISM STUDIES-LAB:
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
162-4 - Aerobic Aquatic
MOBILITY STUDIES:
163-1 - Leaching and Ad-
sorption /Desorpt ion
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
V
Composition
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TEP
TEP
Does EPA Have Data
To Satisfy This
Use 2/ Requirement? (Yes, Bibliographic
Pattern No or Partially) Citation
A,B,D,E,F,G,H
-
A,B,D,G
A,G
A,E,F
A,B,E,F,G,H
A
D,G
D,G
A,B,D,E,F,G,H
A
A
No
No
No
No
Yes GS0104080
No5/
No
No
Partial6/ 00068214
No
No
Must Additional
Data be Submitted
Under FIFRA Section
3(c)(2)(B)?
Yes3a/
Yes3a/
Yes39"/
Yes2f/,V
No
Yes39/
Yes3/
Yes3/
Yes3^/
YesV
Reserved^/
103
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TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORFDN
Data Requirement
Conposition
Use £/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data be Submitted
Under FIFRA Section
3(c)(2)(B)?
§158.130 Environmental Fate
(continued)
DISSIPATION STUDIES-FIELD;
164-1 - Soil
164-2 - Aquatic (Sediment)
164-3 - Forestry
164-4 - Combination and
Tank Mixes
164-5 - Soil, Long-term
ACOJMULATION STUDIES:
TEP
TEP
TEP
TEP
TEP
A,B,H
D
G
165-1 - Rotational Crops
(Confined)
165-2 - Rotational Crops
(Field)
165-3 - Irrigated Crops
165-4 - In Fish
164-5 - In Aquatic Non-
Target Organisms
PAIRA
TEP
TEP
TGAI or PAIRA
TEP
A,B,D,G
A,B,D.G
No
Partial
Partial^/
Not Applicable
No
No
No
Not Applicable
No
Yes
00091852
00092002
00092002
YesV
Reserved12/
Yes3/,lV
Yes7/
104
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TABLE A
Generic Data Requirements For Trichlorfon
158.130 Environmental Fate
(continued)
V Composition: TGAI = Technical grade of the active
ingredient; PAIRA = Pure active ingredient, radiolaheled;
TEP = Typical end-use product.
_£/ The use patterns are coded as follows:
A = Terrestrial, Food Crop; B = Terrestrial, Non-Food;
C = Aquatic, Food Crop; D = Aquatic, Non-Food; F = Greenhouse,
Food crop; F = Greenhouse, Non-Food; G = Forestry;
H = Domestic Outdoor; I = Indoor.
2/ Data must he submitted no later than June, 1987 .
3 a/ The Agency is concerned about the potential contamination of
ground water by trichlorfon and its metabolites. Data re-
quired for the evaluation of the potential for contamination
are being required on an accelerated basis. These data will
be required to be submitted as follows:
0 Hydrolysis (161-1), Photodegradation (161-2 ,-3 ,-4 ) , and
Mobility (163-1) must be submitted no later than
December, 1984. .
0 Soil Metabolism (162-1,-2), Field Dissipation (164-1,
-3) must be submitted no later than June, 1986
^J Not required unless used in greenhouses.
_|V The anaerobic aquatic metabolism data may be substituted
for the anaerobic soil metabolism data, but the reverse is
not permissible.
£/ Study (00068214) partially fulfills mobility data require-
ments for terrestrial, food crop; terrestrial, non-food;
and forestry use patterns, by providing information on the
rapid leaching of trichlorfon in five soil types by soil
thin layer chromatography. To satisfy mobility data
requirements for terrestrial, food crop; terrestrial, non-
food; and forestry use patterns, an additional study in
which the mobility of trichlorfon aged in a sandy loam soil
is assessed by using either soil TLC or soil column
techniques is required. Additional, adsorption/desorption
(batch equilibrium) studies are required on four soils,
105
-------
preferably a sand (agricultural), sandy loam, silt loam,
clay or clay loam for domestic outdoor and greenhouse uses
and on one aquatic sediment obtained from, or representative
of, the aquatic use area for aquatic non-food crop use
pattern.
]_/ Data requirement depends on the results of the laboratory
studies.
£/ Terrestrial field dissipation studies are required for:
(1) terrestrial, food crop uses; representative use pattern
sites should include field vegetable crops, orchard crop
(citrus) and pasture grasses, (2) terrestrial, non-food
' uses; representative use pattern sites should include
tobacco and turf (golf courses) and, (3) domestic outdoor
uses; representative use pattern sites should include
lawns.
V Study (00091852) partially fulfills field dissipation-
aquatic (sediment) data requirements by providing infor-
mation showing that the SC/S formulation of trichlorfon
did not persist in fish rearing pond water or in mud
under alkaline conditions. Two additional aquatic field
dissipation studies are required for two different fish
rearing ponds under acidic conditions (pH 5-6) which are
representative of the fish rearing ponds for which there
is a registered parasiticide use.
1°/ Study (00092002) was reviewed and is considered scientifi-
cally valid. However, this study was conducted with the
SC/S formulation of trichlorfon, which is not currently
registered for forestry use. Therefore forestry dissipa-
tion studies are required for the end-use product with
the largest amount of trichlorfon for which there is a
registered use.
H/ No data were submitted; however, the data requirements
are waived based on the aerobic soil metabolism study
which demonstrated that £50% of the trichlorfon initially
appplied would be present in soil when a subsequent
application would occur.
12/ Reserved pending results of 165-1.
13/ This data requirement depends on the results of 63-11 and
161-1. No data on the accumulation of trichlorfon in fish
will be required if trichlorfon has a half-life of less
than 4 days in water or an octanol water partition coeffi-
cient of less than 1000.
106
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
V Use £/ Requirement? (Yes, Bibliographic
Pattern No or Partially) Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
158.135 Toxicology
ACUTE TESTING;
81-1 - Acute Oral Toxicity - Rat TGAI
81-2 - Acute Dermal Toxicity TGAI
Rabbit
81-3 - Acute Inhalation Toxicity TGAI
- Rat
81-7 - Delayed TGAI
Neurotoxicity - Hen
SUBCHRONIC TESTING;
82-1 - 90-Day Feeding - TGAI
Rodent, Non-rodent
82-2 - 21-Day Dermal Rabbit TGAI
82-3 - 90-Day Dermal Rabbit TGAI
82-4 - 90-Day Inhalation - TGAI
Rat
82-5 - 90-Day Neurotoxicity - TGAI
Hen/Mammal
A,B,D,E,F,G,H Yes
A,B,D,E,F,G,H Yes
A,B,D,E,F,H
A,E
NO
A,B,D,E,F,G,H Yes
No
A,B,D,E,F,G,H No
A,B,D,E,F,G,H No
A,B,D,E,F,G,H No
A,B,D,E,F,G,H No
00081186
00005494
GS0104069
GS0104070
GS0104071
GS0104072
GS0104069
GS0104070
GS0104073
No
No
Yes
No
Yes
Yes
Yes
Yes
Yes
107
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
\/ Use 2/ Requirement? (Yes,
Pattern No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?3/
§158.135 Toxicology
(continued)
CHRONIC TESTING;
83-1 - Chronic Toxicity - TGAI
83-2 - Oncogenicity - TGAI
2 species: Rat and
mouse preferred
83-3 - Teratogenicity - TGAI
2 species
83-4 - Reproduction - Rat TGAI
2-generation
MUTAGENICITY TESTING;
84-2 - Gene Mutation TGAI
84-2 - Chromosomal Aberration TGAI
84-2 - Other Mechanisms of TGAI
Mutagenicity
A,B,,D,E,F,G,H No
A,B,D,E,F,G,H No
A,B,D,E,F,G,H Partial
A,B,D,E,F,G,-H Yes
A,B,D,E,F,G,H Yes
A,B,D,E,F,G,H No
A,B,D,E,F,G,H Yes
00063192 V
GS0104074
GS0104075
GS0104076
00028625
GS010477
00028625
GS0104077
GS0104078
GS0104079
Yesf/
Yes
YesV
No
No
Yes
No
108
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TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORFON
Dees EPA Have Data Must Additional
To Satisfy This Data Be Submitted
\/ Use 2/ Requirement? (Yes, Bibliographic Under FIFRA Section
Data Requirement Composition Pattern No or Partially) Citation 3(c) (2) (B)?3/
SPECIAL TESTING;
85-1 - General Metabolism PAI or A,B,D,E,F,G,H No - Yes
PAIRA
85-2 - Domestic Animal Safety Choice A,B,D,G,H No - Yes
V Composition: TGAI = Technical grade of active ingredient; PAI = Pure active ingredient; PAIRA = Pure active
ingredient, radiolabeled; Choice = Choice of several test substances determined on a case-by-case basis.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic,
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H =
Domestic Outdoor; I = Indoor.
V Data must be submitted no later than June . 1 987 •
_4/ Two species are required: one rodent, rat preferred; and one non-rodent which must be the dog.
5/ The gavage portion of this study is valid but the feeding portion is considered inadequate.
6/ Data from an adequate dietary study in the rat must be submitted.
109
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TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORFON
Does EPA Have Data
To Satisfy This
V Use 2/ Requirement? (Yesf Bibliographic
Must Additional
Data Be Submitted
Under FIFRA Section
Data Requirement
§158.140 Reentry Protection
132-1 - Foliar Dissipation
132-1 - Soil Dissipation
133-3 - Dermal Exposure
133-4 - Inhalation Exposure
Composition
TEP
TEP
TEP
TEP
Pattern
A,B,D,G
A,B,D,G
AfB,D,G
A,B,D,G
No or Partially)
No
No
No
No
Citation 3(c)(2)(B)?V
No
No
No
No
_!/ Composition: TEP = Typical end-use product
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic,
Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H =
Domestic Outdoor; I = Indoor.
3/ No data were submitted; however, data are not being required at this time because the toxicity of trichlorfon does
not exceed subpart K requirements for reentry. These data may be required after other data required under this
standard have been reviewed and evaluated.
110
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Does EPA Have Data Must Additional
To Satisfy This Data be Submitted
V Use 2/ Requirement? (Yes, Bibliographic Under FIFRA Section
Data Requirement Composition Pattern No or Partially) Citation 3(c) (2) (B)?3/
§158.145 Wildlife and
Aquatic Organisms
AVIAN AND MAMMALIAN TESTING
71-1 - Acute Avian Oral TGAI A,B,G Yes 00073683
Toxicity
71-2 - Avian Subacute Dietary TGAI A,B,G,I Yes 00034769
Toxicity
71-3 - Wild Mammal Toxicity TGAI A,B,G Not Required
71-4 - Avian Reproduction TGAI A,B,G Not Required
71-5 - Simulated and Actual TEP A,B,G Not Required
Field Testing -
Mammals and Birds
AQUATIC ORGANISM TESTING
72-1 - Freshwater Fish TGAI A,B,D,G,I Yes 00091881
Acute Toxicity 00091766
GS0104081
00065495
-do- TEP D,G Yes 00091766
GS0104081
No
No
No
No
111
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORFON
Data Requirement
Composition
V
Use
Pattern
Does EPA Have Data Must Additional
To Satisfy This Data be Submitted
Requirement? (Yes, Bibliographic Under FIFRA Section
No or Partially) _ Citation _ 3(c) (2) (B)?3/
§158.145 Wildlife and
Aquatic Organisms
(continued)
72-2 - Acute Toxicity to TGAI
Freshwater
Invertebrates
-do- TEP
72-3 - Acute Toxicity TGAI
Estuarine and
Marine Organisms
72-4 - Fish Early Life TGAI
Stage and Aquatic
Invertebrate Life-Cycle
72-5 - Fish - Life-Cycle TGAI
A,B,D,C,I
Yes
D,G Yes
A,B,D,G Not Required
A,B,D,G
A,B,D,G
72-6 - Aquatic Organism
Accumulation
TGAI, PAR or
Degradation A,B,D,E
Product
72-7 - Simulated or Actual TEP
Field Testing -
Aquatic Organisms
A,B,D,G
No
No
No
No
GS0104081
GS01040R1
No
No
YesV
Reserved _•>/
Reserved _5/
Reserved *V
112
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Table A
Generic Data Requirements for Trichlorfon
158.145 Wildlife and Aquatic Organisms
(continued)
!_/ Composition: TGAI = Technical grade of the active ingre-
dient; PAI = pure active ingredient; TEP = Typical end-
use product;
2_l The use patterns are coded as follows: A = Terrestrial,
Food Crop; B = Terrestrial, Non-Food Crop; C = Aquatic
Food Crop; D = Aquatic, Non-Food Crop; E = Greenhouse,
Food Crop; F = Greenhouse, Non-Food; G = Forestry; H =
Domestic Outdoor; I = Indoor.
3y Data must be submitted no later than June , 1 987
4_/ Data requirement is limited to the aquatic invertebrate
life cycle test; use patterns - A,B,D,E.
_5/ Reserved pending submission of appropriate environmental
fate studies (e.g., dissipation and hydrolysis studies)
which are needed to determine if hazardous concentrations
of trichlorfon will reach or accumulate in the aquatic
environment when products are used as directed.
6/ Reserved pending results of 72-4.
113
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TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORPON
Data Requirement
Conposition
Does EPA Have Data Must Additional
To Satisfy This Data be Submitted
V Use £/ Requirement? (Yes, Bibliographic Under FIFRA Section
Pattern No or Partially) Citation 3(c) (2) (B)?3/
§158.150 Plant Protection
121-1 - TARGET AREA EP
PHYTOTOXICITY
NONTARGET AEA PHYTOTOXICITY
TIER I
122-1 - Seed Germination/ TGAI
Seedling Emergence
No
No
No 4/
No V
122-1
122-2
123-1
123-1
123-2
124-1
124-2
- Vegetative Vigor
- Aquatic Plant Growth
TIER II
- Seed Germination/
Seedling Emergence
- Vegetative Vigor
- Aquatic Plant Growth
TIER III
- Terrestrial Field
- Aquatic Field
TGAI
TGAI
TGAI
TGAI
TGAI
TEP
TEP
No
No
No
No
No
No
No
No 4/
No J/
No £/
No 4/
No £/
No V
NoJ/
V Composition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
EP = End-use product.
£/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food Crop;
C = Aquatic, Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food;
G = Forestry; H = Domestic Outdoor; I = Indoor.
V Reserved.
"*/ These requirements are generally not required unless it is believed there is a phototoxicity problem.
1 1 A
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR TRICHLORFON
Data Requirement
V Use
Composition Pattern
Does EPA Have Data Must Additional
To Satisfy This Data be Submitted
Requirement? (Yes, Bibliographic Under FIFRA Section
No or Partially) _ Citation _ 3(c) (2) (B)?3/
§158.155 Nontarget Insect
NONTARGET INSECT TESTING -
POLLINATORS;
141-1 - Honey bee acute
contact
141-2 - Honey bee - toxicity
of residues on
foliage
TGAI
TEP
A,B,G,H
A,B,G,H
141-3 - Wild bees important in
alfalfa pollination -
toxicity of residues
on foliage TEP
141-4 - Honey bee subacute
feeding study [Reserved] V
A,B,G,H
141-5 - Field testing for
pollinators
TEP
A,B,G,H
Yes
Yes
00036935
00060628,
05000837
Not Required
Yes
05004412
No
No
No
115
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TABLE A
GENERIC DATA REQUIREMENTS FOR TRICHLORPON
Data Requirement
Use2/
Composition1/ Pattern
Does EPA Have Data Must Additional
To Satisfy This Data be Submitted
Requirement? (Yes, Bibliographic Under FIFRA Section
No or Partially) Citation 3(c) (2) (B)?3/
§158.155 Nontarget Insect
(continued)
NONTARGET INSECT TESTING -
AGUATIC INSECTS
142-1 - Acute toxicity to
aquatic insects
142-2 - Acute insect
life-cycle study
[Reserved] V
[Reserved] 5/
142-3 - Simulated or actual
field testing for
aquatic insects [Reserved]
143-1 - NONTARGET INSECT TESTING -
thru
143-3
PREDATORS AND PARASITES
[Reserved] V
_!/ Composition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
EP = End-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food Crop;
C = Aquatic, Food Crop; D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food;
G = Forestry; H = Domestic Outdoor; I = Indoor.
V Reserved.
4/ Reserved pending development of test methodology.
V Reserved pending Agency decision as to whether the data requirements should be established.
116
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Ill. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Note: This Section applies only to manufacturing-use
products, not end-use products.
A necessary first step in determining which statements must
appear on your product's label is the completion and submission
to EPA of product-specific data* listed on the form entitled
"Product Specific Data Report" (EPA Form 8580-4, Appendix III-l)
to fill "gaps" identified by EPA concerning your product. Under
the authority of FIFRA Section 3(c)(2)(B), EPA has determined
that you must submit these data to EPA in order to register or
reregister your product(s). All of these data must be submitted
not later than six months after you receive this guidance document
"Product-Specific Data Requirements for Manufacturing-Use
Products" appearing in Table B permit you to determine which
product-specific data you must submit. This can be done by
examining the entries in the column of those tables entitled
"Must Data Be Submitted Under S3(c)(2)(B)."
V Product specific data pertains to data that support the
formulation which is marketed; it usually includes product chemist)y
data and acute toxicology data.
117
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRICHLOFON
§158.120 - PRODUCT CHEMISTRY
Guideline Citation and Test Guidelines Are Data Footnote
Name of Test Substance V Status Required V Number
Yes No
PRODUCT IDENTITY:
61-1 - Identity of Ingredients MP R /X/ /~7
61-2 - Statement of Composition MP R /X/ /~7
61-3 - Discussion of Formation of MP R /X/ / /
Ingredients
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis MP R /X/ _/~7
62-2 - Certification of Limits MP R /X/ f~J
62-3 - Analytical Methods for MP R /X/ /_/
Enforcement of Limits
Physical and Chemical Characteristics
63-2 - Color MP R /X/ /~7
63-3 - Physical State MP R /X7 7~7
63-4 - Odor MP R /V /~7
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRICHLORPON
§158.120 - PRODUCT CHEMISTRY (Con't)
Guideline Citation and Test Guidelines
Name of Test Substance V Status
Physical and Chemical Characteristics
(Continued)
63—7 Density f Bulk Density, or
Specific Gravity
£O TO _ T-*H
63 14 Oxidizing or Reducing
Action
63-15 - Flammability
63-16 - Explodability
DJ i i storage otauiiity
DJ 10 — viscosity
63 19 Miscibility
63—20 Corrosion Characteristics
Other Requirements:
64—1 SuDmittal of samples
MP R
MP R
MP CR
MP CR
MP R
MP R
MP CR '
MP CR
MP R
PAI CR
I/ Composition: MP = Manufacturing-Use Prouct; PAI = Pure Active
2/ Data must be submitted no later than December, 1984
Are Data Footnote
Required 2/ Number
Yes No
/v n
/v n
A/ n
ffl f~7
/xz n
/w n
/xz n
A/ n
/*/ n
n /v
Ingredient1
1.19
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRICHLORFON
V
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
Bibliographic
Must Additional
Data Be Submitted
Under FIFRA Section
Data Requirement Composition
158.135 Toxicology
ACUTE TESTING:
81-1 - Oral LD5Q - Rat MP
81-2 - Dermal 11)50 - Rabbit MP
No or Partially) Citation
Yes 00081186
00005494
GS0104069
GS0104070
GS0104071
Yes ' GS0104072
GS0104069
GS0104070
3(c)(2)(B)?2/
No
No
81-3 - Inhalation IC$Q - Rat
81-4 - Primary Eye
Irritation - Rabbit
81-5 - Primary Dermal
Irritation - Rabbit
81-6 - Dermal Sensitization -
Guinea Pig
MP
MP
MP
MP
No
No
No
No
Yes
Yes
Yes
Yes
_!/ Composition: MP = Manufacturing product
2/ Data must be submitted no later then te C3 mbe r , 1 984 •
120
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IV. SUBMISSION OF REVISED LABELING AND PACKAGING INFORMATION
Note: This section applies to end-use products only to the
the extent described under Section II of this document.
Otherwise, the following information pertains exclusively to
manufacturing-use products.
The Agency requires applicants for registration or reregistra-
tion to ensure that each label (1) contains accurate, complete,
and sufficient instructions and precautions, reflecting the
results of data concerning the product and its ingredients, and
(2) incorporates labeling format and terminology which are suffi-
ciently standardized to avoid user confusion.
As part of your application, you will be required to submit
draft labeling consistent with: applicable product-specific
data; the precautionary statements and use directions; and the
regulations concerning classification [40 CFR Sl62.11(c)], pack-
aging [40 CFR §162.16], and labeling [40 CFR §162.10, Appendix
IV-1 an IV-2], as indicated by the following paragraphs of this
chapter of the guidance document.
If owners of currently registered products fail to submit
revised labeling and packaging information complying with this
Section and/or Section II, EPA may issue a notice of intent to
cancel the registration under FIFRA §6(b)(l).
A. Label Contents
40 CFR §162.10 (Appendix IV-1) requires that certain spe-
cific labeling statements must appear at certain locations
on the label. This is referred to as format labeling.
Specific label items listed below are keyed to Tables D, E,
and F (Appendix IV-2).
Item 1. PRODUCT NAME - The name, brand, or trademark is
required to be located on the front panel, preferably centered
in the upper part of the panel. The name of a product will
not be accepted if it is false or misleading. See Appendix
IV-1. [40 CFR §162.10(b)]
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
See Appendix IV-1. [40 CFR §162.10(c)]
Item ?.. NET CONTENTS - A net content statement is required
on all labels. The preferred location is the bottom of the
front panel immediately above the company name and address,
or at the end of the label text. The net contents must be
stated in terms of weight, expressed as avoirdupois pounds
121
-------
and ounces, and stated in terms of the largest suitable unit,
i.e., "1 pound 10 ounces" rather than "26 ounces." In
addition to the required units specified, net contents may be
expressed in metric units. See Appendix IV-1. [40 CFR
S162.10(d)]
Item 4. EPA REGISTRATION NUMBER - The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase "EPA Registration No.," or "EPA
Reg. No." The registration number must be set in type of a
size and style similar to other print on that part of the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency. See Appendix IV-1.
[40 CFR S162.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment
number, preceded by the phrase "EPA Est." is the final estab-
lishment at which the product was produced, and may appear
in any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of
the package if the EPA establishment registration number on
the immediate container cannot be clearly read through such
wrapper or container. See Appendix IV-1. [40 CFR S162.10(f)]
Item 6. INGREDIENT STATEMENT - An ingredient statement
is required on the front panel and must contain the name and
percentage by weight of each active ingredient and the total
percentage by weight of all inert ingredients. The preferred
location is immediately below the product name. The ingredient
statement must run parallel with, and be clearly distinguished
from, other text on the panel. It must not be placed in the
body of other text. See Appendix IV-1. [40 CFR 162.10(g)]
Item 6A. POUNDS PER GALLON STATEMENT - For liquid
agricultural formulations, the pounds per gallon of active
ingredient must be indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS - All labels
are required to have precautionary statements grouped together
on the front panel, preferably within a block outline. The
table below shows the minimum type size requirements on
various size labels, as set forth in the Regulations.
122
-------
Size of Label
on Front Panel
in Square Inches
5 and under
above 5 to 10
above 10 to 15
above 15 to 30
over 30
Signal Word as Re-
quired Minimum Type
Size All Capitals
6 point
10 point
12 point
14 point
18 point
"Keep Out of Reach
of Children"
as Required
6 point
6 point
8 point
10 point
12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - All labels are
required to have the statement "Keep Out of Reach of Children"
located on the front panel above the signal word except where
contact with children during distribution or use is unlikely.
See Appendix IV-1. [40 CFR §162.10(h)(1)(ii))
Item 7B. SIGNAL WORD - The signal word (Caution, Warning,
or Danger) is required on the front panel immediately below
the child hazard warning statement. See Appendix IV-1.
[40 CFR §162.10 (h)(l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, inhala-
tion, or dermal toxicity, the word "Poison" shall appear on
the label in red on a background of distinctly contrasting
color and the skull and crossbones shall appear in immediate
proximity to the word poison. See Appendix IV-1. [40 CFR
STATEMENT OF PRACTICAL TREATMENT - A statement
treatment (first aid or other) shall appear on
pesticide products in toxicity Categories I,
See Appendix IV-1. [40 CFR 5162,10(h)(1) (iii)]
Item 7D.
of practical
the label of
II, and in.
Item 7E. REFERRAL STATEMENT - The statement "See Side
(or Back) Panel for Additional Precautionary Statements" is
required on the front panel for all products, unless all
required precautionary statements appear on the front panel.
See Appendix IV-1. [40 CFR §162.10(h)(1)(iii)]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING - The
precautionary statements as listed below must appear together
on the label under the heading "PRECAUTIONARY STATEMENTS."
The preferred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the three hazard warning statements must be headed by the
appropriate hazard title. See Appendix IV-1. [40 CFR §162.10
123
-------
Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a
hazard exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard, the
route(s) of exposure and the precautions taken to avoid
accident, injury or damage. See Appendix IV- 1. [40 CFR S162.10
Item 8B. ENVIRONMENTAL HAZARD - Where a hazard exists to
non-target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. See Appendix IV- 1. [40 CFP
Item 8C. PHYSICAL OR CHEMICAL HAZARD
1. Flammability statement. Precautionary statements
relating to flammability of a product are required
to appear on the label if it meets the criteria in
Appendix IV-3. The requirement is based on the results
of the flashpoint determinations and flame extension
tests required to be submitted for all products.
These statements are to be located in the side/back
panel precautionary statements section, preceded by
the heading "Physical/Chemical Hazards." Note that
no signal word is used in conjunction with the flam-
mability statements.
2. Criteria for declaration of non-f lammability . The
following criteria will be used to determine if a
product is non-flammable:
a. A "non-flammable gas" is a gas (or mixture of
gases) that will not ignite when a lighted match
is placed against the open cylinder valve.
b. A "non-flammable liquid" is one having a flash-
point greater than 350°F (177°C) as determined
by the method specified in 40 CFR §163 .61-8 (c) ( 13 )
( ii) of Subpart D.
c. A "non-flammable aerosol" is one which meets the
following criteria:
i. The flame extension is zero inches, using the
method specified in 40 CFR S163 .61-8 ( c) ( 13 ) ( ii ) ;
ii. There is no flash back; and
iii. The flashpoint of the non-volatile liquid
component is greater than 350°F (177°C),
determined by the method specified in 40 CFR
S163.61-8(c)(13)(i).
124
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3. Declaration of non-flammability. Products which meet
the criteria for non-flamroability specified above may
bear the notation "non-flammable" or "nonflammable
(gas, liquid, etc.)" on the label.
It may appear as a substatement to the ingredients
statement, or on a back or side panel, but shall not
be highlighted or emphasized (as with an inordinately
large type size) in any way that may detract from
precaution.
4. Other physical/chemical hazard statements. When
chemistry data submitted in accordance with 40 CFR
§163,61-10(c) demonstrate hazards of a physical or
chemical nature other than flammability, appropriate
statements of hazard will be prescribed. Such
statements may address hazards of explosivity,
oxidizing or reducing capability, or mixing with
other substances to produce toxic fumes.
Item 9. MISUSE STATEMENT - The following statement is
required on your label: "It is a violation of Federal law to
use this product in a manner inconsistent with its labeling."
See Appendix IV-1. [40 CFR §162.10(1)(2)(ii)]
Item 10A. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage and disposal statements. These
statements are developed for specific containers, sizes, and
chemical content. Make certain that the statement you use
pertains specifically to your product. These instructions
must be grouped and appear under the heading "Storage and
Disposal" in the directions for use. This heading must be
set in the same type sizes as required for the child hazard
warning. Refer to Appendix IV-5 for the latest specific
storage and disposal product label statements.
Item 10B. DIRECTIONS FOR USE - Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate to
protect the public from fraud and from personal injury and to
prevent unreasonable adverse effects on the environment. See
Appendix IV-1. [40 CFR S162.10]
B. Collateral Information
Bulletins, leaflets, circulars, brochures, data sheets,
flyers, and other graphic printed matter which is referred to
on the label or which is to accompany the product are termed
collateral labeling. Such labeling ma^ not bear claims or
representations that differ in substance from those accepted
in connection with registration of the product. It should be
made part of the response to this notice and submitted for review.
125
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V. INSTRUCTIONS FOR SUBMISSION
All applications prepared in response to this Notice should
be addressed as follows:
Product Manager William H. Miller
Phone No. (703) 557-2600
Registration Division (TS-767)
Office of Pesticide Programs
Environmental Protection Agency
Washington, D.C. 20460
For each product for which continued registration is desired:
1. Within 90 days from receipt of this document, you must
submit the "FIFRA Section 3(c)(2)(B) Summary Sheet" EPA
Form 8580-1. Refer to Appendix II-2 with appropriate
attachments.
2. Within 6 months from receipt of this document registrants
must submit:
a. Confidential Statement of Formula, EPA Form 8570-4.
b. Product Specific Data Report, EPA Form 8580-4 (Appendix
III-l).
c. Two copies of any required product-specific data.
d. Two copies of draft labeling, including the label and
associated brochures. If current labeling conforms
to the requirements of this guidance document and the
results of the short-term data, the registrant may
submit such labeling. (End-use product labeling
needs to comply specifically with the instruction in
Section II of this guidance document.) The labeling
should be either typewritten text on 8-1/2 x 11 inch
paper or a mcckup of the labeling suitable for
stortage in 8-1/2 x 11 inch files. The draft label
must indicate the intended colors of the final label,
clear indication of the front panel label, and the
intended type sizes of the text.
3. Within the time set forth in Table A, all generic data
must be submitted by the affected registrant(s).
Note; If for any reason any required test is delayed or aborted
so that meeting the agreed submission time will be delayed,
notify the Product Manager listed above.
After the Supreme Court has ruled on the Monsanto Decision,
you will be informed as to when you must submit your Application
for Amended Pesticide Registration (EPA Form 8570-1) and the
associated data support information.
126
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APPENDIX II-l
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Trichlorfon Standard
00005296 Arthur, B.W.; Casida, J.E. (1957) Metabolism and selectivity of O,
O-Dimethyl 2,2,2-trichloro-l-hydroxyethyl phosphonate and its
acetyl and vinyl derivatives. Journal of Agricultural and Food
Chemistry 5(3):186-192. (Also In unpublished submission re-
ceived Aug 18, 1966 under 7F0612; submitted as report number
1241 by Chemagro Corp., Kansas City, Mo.; CDL:090796-U)
00005297 Robbins, W.E.; Hopkins, T.L.; Eddy, G.W. (1956) The metabolism of
P32-labeled Bayer L 13/59 in a cow. Journal of Economic En-
tomology 49(6):801-806. (Also In unpublished submission re-
ceived Aug 18, 1966 under 7F0612; submitted as report number
1635 by Chemagro Corp., Kansas City, Mo.; CDL:090796-V)
00005300 Metcalf, R.L.; Fukuto, T.R.; March, R.B. (1959) Toxic action of
dipterex and DDVP to the house fly. Journal of Economic En-
tomology 52(l):44-49. (Also In unpublished submission re-
ceived Aug 18, 1966 under 7F0612; submitted as report number
2217 by Chemagro Corp., Kansas City, Mo.; CDL:090796-Y)
00005494 MacDougall, D. (1962) Acute Toxicity of Some Organophosphorous In-
secticides to Rats. (Unpublished study including letter dated
Nov 23, 1962 from D. MacDougall to Dr. Jasper, received Nov 26,
1962 under unknown admin, no.; prepared by Chemagro Corp., sub-
mitted by Bayvet, Shawnee Mission, Kans.; CDL:109105-A)
00028625 Simmon, V.F. (1979) In vitro Microbiological Mutagenicity and Un-
scheduled DNA Synthesis Studies of Eighteen Pesticides: Report
No. EPA-600/1-79-041. (Unpublished study including submitter
summary, received Apr 3, 1980 under 279-2712; prepared by SRI
International, submitted by FMC Corp., Philadelphia, Pa.; CDL:
099350-A)
00034769 , Hill, E.F.; Heath, R.G.; Spann, J.W.; et al. (1975) Lethal Dietary
Toxicities of Environmental Pollutants to Birds. By U.S. Fish
and Wildlife Service, Patuxent Wildlife Research Center. Wash-
ington, D.C.: U.S. FWS. (Special Scientific Report—Wildlife
No. 191; also In unpublished submission received Mar 28, 1979
under 3125-236; submitted as report number 33423a by Mobay
Chemical Corp., Kansas City, Mo.; CDL:237905-B)
; -V.rfv ' '•
00036935 Atkins, E.L.; Greywood, E.A.; Macdonald, R.L. (1975) Toxicity of
Pesticides and Other Agricultural Chemicals to Honey Bees: Labo-
ratory Studies. By University of California, Dept. of Entomolo-
gy. (UC/Cooperative Extension Leaflet 2287; published study.)
127
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Trichlorfon Standard
00060628
00063192
00065495
00068214
00073683
00081186
00091766
Johansen, C.A.; Eves, J. (1965) Bee Poisoning Investigations, 1965:
Report No. G-1705; Report No. 17338. (Unpublished study, in-
cluding letter dated Jun 12, 1973 from C.A. Johansen to A.D. Co-
hick, received Mar 27, 1974 under 4F1485; prepared by Washington
State Univ., Dept. of Entomology, submitted by Chemagro Corp.,
Kansas City, MO.; CDL:092011-1)
Staples, R.E.; Kellam, R.G; Baseman, J.K. (1976) Developmental
toxicity in the rat after ingestion of gavage of organophosphate
pesticides (Dipterex, Imidan) during pregnancy. Environmental
Health Perspectives 13(Feb):133-140. (Also In unpublished
submission received Apr 18, 1978 under 476-1917; submitted by
Stauffer Chemical Co., Richmond, Calif.; CDL:234110-D)
Pickering, Q.H.; Henderson, C.; Lemke, A.E. (1960) The Toxicity
of Organic Phosphorus Insecticides to Different Species of
Warm Water Fishes. (U.S. Public Health Service, R.A. Taft
Sanitary Engineering Center, unpublished study including sub-
mitter summary, received Apr 7, 1977 under 3125-183; submitted
as report number 9282 by Mobay Chemical Corp., Kansas City, Mo.;
CDL:229299-A)
Thornton, J.S.; Hurley, J.B.; Obrist, J.J. (1976) Soil Thin-layer
Mobility of Twenty Four Pesticide Chemicals. (Unpublished
study received Jul 11, 1977 under 3125-315; submited as report
number 51016 by Mobay Chemical Corp., Kansas City, Mo.;
CDL:230908-1)
Schafer, E.W. (1972) The Acute Oral Toxicity of 369 Pesticidal,
Pharmaceutical and Other Chemicals to Wild Birds. (Toxicology
and Applied Pharmacology 21:315,316,319. Incomplete; also in
unlisted sutmission received Mar 21, 1977 under 352-338; sub-
mitted by E.I. du Pont de Nemours & Co., Wilmington, Del.;
CDL.-228727-AI)
DuBois, K.P.; Cotter, G.J. (1955) Studies on the toxicity and mech-
anism of action of dipterex. American Medical Association
Archives of Industrial Health 11(Jan):53-60. (Also in unpublished
submission received Feb 13, 1961 under 3125-77; submitted as re-
port number 467 by Mobay Chemical Corp., Kansas City, Mo.; CDL:
100895-B)
Lamb, D.W.; Roney, D.J. (1972) Acute Toxicity of Dylox (R) Tech-
nical and Dylox 80% SPA-oil to Fish. -.(Unpublished study received
Sep 1, 1972 under 3125-278; submitted as report number 32807 by
Mobay Chemical Corp., Kansas City, Mo.; CDL:050510-B)
128
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Trichlorfon Standard
00091787 Metcalf, R.L.; Winton, M.Y.; Fukuto, T.R. (1958) Dipterex Residues
on Citrus and Alfalfa as Studied by P 32-labeled Compound.
(Unpublished study received Aug 18, 1966 under 3125-49; prepared
by Univ. of California—Riverside, Dept. of Entomology, Citrus
Experiment Station; submitted as report number 2333 by Mobay
Chemical Corp., Kansas City, Mo.; CDL:090790-C)
00091852 Olson, T.J. (1968) A Study of DDVP Formation Resulting from Tri-
chlorfon Treatment of Alkaline Pond Water. (Unpublished study
received Sep 19, 1969 under 3125-143; submitted as report number
21808 by Mobay Chemical Corp., Kansas City, Mo.; CDL:102088-C)
00091881 Henderson, C.; Pickering, Q.H.; Tarzwell, C.M. (1959) The Toxicity
of Organic Phosphorus and Chlorinated Hydrocarbon Insecticides
to Fish: Mobay 4276a. (U.S. Public Health Service, Robert A.
Taft Sanitary Engineering Center, Water Supply and Water Pollu-
tion Research, Bioassay Application Studies; unpublished paper
presented at the Second Seminar on Biological Problems in Water
Pollution; Apr 21, 1959; Cincinnati, Ohio. Unpublished study
received Mar 4, 1966 under unknown administrative number; sub-
mitted as report number 4276 by Mobay Chemical Corp., Kansas
City, Mo.; CDL:110547-B)
00092002 Grimble, D.G.; Sykes, R.B., Jr.; Devine, J.M.; et al. (1972) An
Evaluation of the Environmental Impact and Efficacy of an Aerial
Application of Trichlorfon (Dylox) against the Gypsy Moth and
Associated Organisms in New York State. (Unpublished study re-
ceived May 20, 1977 under 3125-210; prepared by State Univ. of
New York—Syracuse, Applied Forestry Research Institute, submit-
ted as report number 32702 by Mobay Chemical Corp., Kansas
City, Mo.; CDL:230752-T)
05000837 Johansen, C.A. (1972) Toxicity of field-weathered insecticide
residues to four kinds of bees. Environmental Entomology
1(3):393-384
05004412 Palmer-Jones, T.; Forster, I.W. (1963) Effect on honey bees of
Dipteres, Thiodan, and Phosdrin applied as sprays to white
clover (Trifolium repens), New Zealand Journal of
Agricultural Research 6(3/4):303-306
129
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104001 Thornton, J.S. (1967) Determination of residues of
Trichlorfon in cottonseed by thermionic emission gas
chromatography, Report no. 21386; (Unpublished study received
Oct 16, 1975 under PP#6F1688; submitted by Boychem Corp.;
Chemagro Div.)
GS0104002 Obrist, J.S. (1975) An interference study for the residue
method for Trichlorfon on soybeans, Report no. 44408;
(Unpublished study received Oct 16, 1975 under PP#6F1688,
submitted by Mobay Chemical Corp, Chemagro Agricultural Div.)
4S0104003 Chemagro Agricultural Division (1975) Mobay Chemical Corporation
residue experiment. Report nos. 44411-44429; (Unpublished
study received Oct 16, 1975 under PP#6F1688, prepared by Lake
Ontario Environmental Laboratories).
GS0104004 Chemagro Corp. (1967) Chemagro residue experiment no. KC-505-
67D, Study no. 21502; (Unpublished study received Oct 16,
1975 under PP#6F1688)
GS0104005 Chemagro Corp. (1962) Dylox analytical, residue, and taste
information (peppers and tomatoes), Report no. 8442 and 9014;
(Unpublished study received May 15, 1967 under PP#7F0612)
CDL:RCB 115100.
GS0104006 Chemagro Corp. (1963) Dylox analytical and residue data
(barley, flax, oats, and wheat), Report no. 10081; (Unpublished
study received May 15, 1967 under PP#7F0612) CDL:RCB 115101.
GS0104007 Chemagro Corp. (1975) Dylox analytical and residue data
(cowpeas and lima beans), Report no. 14553; (Unpublished
study received May 15, 1967 under PP#7F0612) CDLiRCB 115102.
GS0104008 Chemagro Corp. (1966) Trichlorfon analytical and residue
information (corn), Report no. 11560; (Unpublished study
received May 15, 1967 under PP#7F0612) CDL:RCB 115107.
GS0104009 Chemagro Corp. (1962) Dylox residue data, (table beets), Report
nos. 9216, 9217, 9218, 9219, 9220, 9522, 9524 and 9528;
(Unpublished study received Aug 30, 1967 under PP#7F0612)
CDL:RCB 115089.
GS0104010 Chemagro Corp. (1962) Dylox residue data (carrots), Report
nos. 8891,8898, 8898, 8901 and 9523; (Unpublished study
received Aug 30, 1967 under PP#7F0612) CDLrRCB 115089.
130
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104011 Chemagro Corp. (1962) Dylox residue data (head and leaf
lettuce), Reports nos. 8555, 8558, 8560, 8562, 8564, 8974 and
9521; (Unpublished study received Aug 30, 1967 under PP#7F0612)
CDL:RCB 115089.
GS0104012 Chemagro Corp. (1962) Dylox analytical, residue, and taste data,
green beans, cauliflower, and kale, Report no. 8996; (Unpublished
study received May 15, 1967 under PP#7F0612) CDL:RCB 115093.
GS0104013 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 14957, 14958 and 14973; (Unpublished study received May
15, 1967 under PP#7F0612) CDL:RCB 115094 and 115102.
GS0104014 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 14885, 14889, 14947 and 14968; (Unpublished study received
May 15, 1967 under PP#7F0612) CDL:RCB 115094 and 115102.
GS0104015 Chemagro Corp. (1962) Dylox analytical, residue and taste
data, green beans, cauliflower, and kale, Report nos. 8894,
8896, 8897 and 8902; (Unpublished study received May 15, 1967
under PP#7F0612) CDLrRCB 115093.
GS0104016 Chemagro Corp. (1962) Dylox analytical, residue and taste
information (peppers and tomatoes), Report nos. 9003 and
8460-8471; (Unpublished study received May 15, 1967 under
PP#7F0612) CDL:RCB 115100.
GS0104017 Chemagro Corp. (1962) Dylox analytical, residue and taste
information (peppers and tonatoes), Report nos. 8472-8481;
(Unpublished study received May 15, 1967 under PP#7F0612)
CDL:RCB 115100.
GS0104018 Chemagro Corp. (1965) Dylox analytical and residue data
(pumpkin), Report nos. 14770, 14939, 14942, 14951-14956 and
14959-14964; (Unpublished study received May 15, 1967 under
PPI7F0612) CDL:RCB 115091.
GS0104019 Chemagro Corp. (1963) Dylox analytical and residue data
(barley, flax, oats and wheat). Report nos. 11538, 11544,
11545, 11561 and 12034; (Unpublished study received May 15,
1967 under PP#7F0612) CDL:RCB 115101.
GS0104020 Chemagro Corp. (1966) Trichlorfon analytical and residue
information (corn) Report nos. 17461 and 17483-17494;
(Unpublished study received May 15, 1967 under PPI7F0612)
CDL:RCB 115107.
131
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104021 Chemagro Corp. (1963) Dylox analytical and residue data
(barley, flax, oats, and wheat); Report nos. 11541, 11542,
11546, 11547 and 11561; (Unpublished study received May 15,
1967 under PP#7F0612) CDLrRCB 115101.
GS0104022 Chemagro Corp. (1963) Dylox analytical and residue data
(barley, flax, oats and wheat), Report nos. 11543, 11549, and
11561; (Unpublished study received May 15, 1967 under PP#7F0612)
CDL:RCB 115101.
GS0104023 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 18836, 17757, 18833 and 18832; (Unpublished study received
May 15, 1967 under PP#7F0612) CDLrRCB 115096 and 115094.
GS0104024 Chemagro Corp. (1966) Trichlorfon analytical and residue
information (corn), Report nos. 17461 and 17483-17494;
(Unpublished study received May 15, 1967 under PP#7F0612)
CDL:RCB 115107.
GS0104025 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 18834, 18835, 18851 and 17459; (Unpublished study received
May 15, 1967 under PP#7F0612) CDL:RCB 115094 and 115096.
GS0104026 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 18814, 18815, and 17457; (Unpublished study received May
15, 1967 under PP#7F0612) CDLrRCB 115094 and 115096.
GS0104027 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas and lima beans, Report
nos. 8973, 8976, 8978, 8997, 8998, 17460, 18816, 18818, 18820,
18831 and 18830; (Unpublished study received May 15, 1967
under PP#7F0612) CDLrRCB 115094 and 115096.
GS0104028 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 8954-8956, 8958, 18812, 18817, 18821-18826 and 17876;
(Unpublished study received May 15, 1967 under PP#7F0612)
CDLrRCB 115094 and 115096.
GS0104029 Chemagro Corp. (1962) Dylox analytical and residue data
(bananas), Report nos. 20413, 20414, 20424, 20425, 20426 and
20427 (Unpublished study received May 15, 1967 under PP#7F0612)
CDLrRCB 115106.
GS0104030 Chemagro Corp. (1963) Dylox analytical and residue data
(barley, flax, oats, and wheat), Report nos. 11540, 11539,
11561 and 12034 (Unpublished study received May 15, 1967
under PP#7F0612) CDLrRCB 115101.
132
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104031 Chemagro Corp. (1962) Dylox residue data (safflower), Report
nos. 11219, 11220, and 11221 (Unpublished study received Aug.
30, 1967 under PP# Section D of 7F0612) CDL:RCB 115089.
GS0104032 Chemagro Corp. (1963) Neguvon Residue information on cattle
tissues (spray), Report nos. 10325, 10411, 10412, 10413, and
12843 (Unpublished study received May 15, 1967 under PP#7F0612)
CDL:RCB 115092.
GS0104033 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
no. 17991 (Unpublished study received May 15, 1967 under
PP#7F0612) CDL:RCB 115094.
GS0104034 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
no. 18884 (Unpublished study received May 15, 1967 under
PP#7F0612) CDL:RCB 115096.
GS0104035 Chemagro Corp. (1966) Co-Rol-Trichlorfon analytical and
residue information on mist spray application to dairy and
beef cattle, Report No. 18495 (Unpublished study received
May 15, 1967 under PPI7F0612) CDL:RCB 115097.
GS0104036 Chemagro Corp. (1964) Neguvon analytical and residue
information on backline application, Report #14412 (Unpub-
lished study received May 15, 1967 under PP#7F0612) CDL:RCB
115103.
GS0104037 Chemagro Corp. (1963) Neguvon residue information on
cattle tissues (spray), Report #18322 (Unpublished study
received May 15, 1967 under PP#7F0612) CDLiRCB 115092.
GS0104038 Chemagro Corp. (1967) Trichlorfon analytical and residue
information for forage crops, cowpeas, and lima beans, Report
nos. 17440, 17970, 18321 and 21289; (Unpublished study received
May 15, 1967 under PP#7F0612) CDL:RCB 115094.
GS0104039 Chemagro Corp. (1962) Dylox (Dipaterex) on bananas, Report
nos. 8839 and 8806; (Unpublished study received Nov. 26, 1962
under PP#0384) CDL:RCB 114214 and 114215.
GS0104040 Chemagro Corp. (1962) Dylox (Dipterex) on bananas, Report
nos. 9121, 9122, 9123, 9124 and 9132; (Unpublished study
received Nov 26, 1962 under PP#0384) CDL:RCB 114214 and
114215.
GS0104041 Chemagro Corp. (1971) Trichlorfon analytical and residue
information on forage crops, Report no. 14770; (Unpublished
study received Aug 17, 1971 under PP#2F1177) CDL:RCB 117411.
133
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104053 Chemagro Corp. (1971) Trichlorfon analytical and residue
information on forage crops, Report nos. 29109, 29111, 29209,
and 29308; (Unpublished study received Aug 17, 1971 under
PP#2F1177) CDLrRCB 117416.
GS0104054 Chemagro Corp. (1971) Trichlorfon analytical and residue
information on forage crops, Report nos. 20997 and 21040;
(Unpublished study received Aug 17, 1971 under PP#2F1177)
CDLrRCB 117411.
GS0104055 Chemagro Corp. (1971) Trichlorfon analytical and residue
information on forage crops, Report no. 29234; (Unpublished
study received Aug 17, 1971 under PP#2F1177) CDL:RCB 117416.
GS0104056 Chemagro Corp. (1970) Trichlorfon analytical and residue
information on peanuts, Report nos. 14393 and 16460; (Unpublished
study received April 27, 1970 under PP#OF0969) CDLrRCB 11614.
GS0104057 Chemagro Corp. (1970) Trichlorfon analytical and residue
information on peanuts, Report nos. 21809 and 24808; (Unpublished
study received April 27, 1970 under PP#OF0969) CDL:RCB 116615.
GS0104058 Chemagro Corp. (1970) Trichlorfon analytical and residue
information on peanuts, Report nos. 25241, 25242, 25278-25284,
25300-25303, and 25306; (Unpublished study received April 27,
1970 under PP#OF0969) CDL:RCB 116615.
GS0104059 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on citrus fruit, Report no. 29411; (Unpublished
study received March 1, 1972 under PP#2F1242) CDLrRCB 117736.
GS0104060 Chemagro Corp. (1972) Trichlorfon analytical and residue
information citrus fruit, Report nos. 21811, 26334, and 27471;
(Unpublished study received March 1, 1972 under PP#2F1242)
CDL:RCB 117733.
GS0104061 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on citrus fruit, Report no. 11908; (Unpublished
study received March 1, 1972 under PP#2F1242) CDLrRCB 117733.
GS0104062 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on lima beans, Report nos. 29213-292215, 29222,
29227, 29322, 29323, and 31455-31459; (Unpublished study
received March 1, 1972 under PP#2F1242) CDL:RCB 117737.
GS0104063 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on lima beans, Report nos. 29213-29215, 29222,
29227, 29322, 29323, and 31625-31631; (Unpublished study
received March 1, 1972 under PP#2F1242) CDL:RCB 117737.
134
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104064 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on citrus fruit, Report nos. 29744, 31326, 31472,
31644, 31930, 29728-29735, 30931, 29211, 29212, 29719 and
29720; (Unpublished study received March 1, 1972 under PP#2F1242)
CDL:RCB 117733 and 117736.
GS0104065 Chemagro Corp. (1972) Trichlorfon analytical and residue
information on citrus fruit, Report No. 29226; (Unpublished
study received March 1, 1972 under PP#2F1242) CDL:RCB 117736.
GS0104066
GS0104067
GS0104068
GS0104069
GS0104070
GS0104071
GS0104072
GS0104073
GS0104074
Chemagro Corp. (1972) Trichlorfon analytical residue information
on citrus fruit, Report no. 29226; (Unpublished study received
March 1, 1972 under PP#2F1242) CDLrRCB 117736.
IR-4 Project (1982) Petition proposing a tolerance for
trichlorfon for use in lowbush blackberry productions, Test nos. 28435,
44241-44246, 45222 and 45223 in Section D; (Unpublished study received
Feb 19, 1982 under PP#2E2646) CDL:RCB 070686.
IR-4 Project (1977) Petition proposing tolerance for trichlorfon
in or on birdsfood trefoil (PR#6021/Seed Crop/Section D; (Unpublished
study received Sept 27, 1977 under PPI7E2008)
Gaines, T.B. 1960. The acute toxicity of pesticides to rats.
Toxicology and Applied Pharmacology 2:88-99. (Also In
unpublished study received August 18, 1966 under 7F0612;
submitted by ?; CDL:090786).
Gaines, T.B. 1969. The acute toxicity of pesticides. Toxicol.
Appl. Pharmacol. 14:515-534.
US-EPA. 1961. "Neguvon. Pharmacology and Toxicology Data.
February 2, 1961." Submitted in support of Petition 7F0612
(EPA Accession #090786.
Edson, E.F. and Noakes, D.N. 1960. The comparative toxicity
of six organophosphorus insecticides in the rat. Toxicol.
Appl. Pharmacol. 2:523-539.
Olajos, E.G., Rosenblum, I., Coulston, F., S. Stromiger, N.
1979. The dose-response relationship of trichlorfon
neurotoxicity in hens. Ecotox. Environ. Safety 3:245-255.
Machemer, L. 1979. Mobay Report No. 69299: "L13/59
(Trichlorfon). Evaluation for Efrbryotoxic and Teratogenic
Effects on Orally Dosed Rabbits,' by Dr. L. Machemer, Bayer
AG Institute fur Toxikologie, (Report No. 8430, June 8, 1979).
Ace. No. 244915.
135
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registration Under the Standard
GS0104075 Staples R.E., Goulding, E.H. 1979. Dipterex teratogenicity
in the rat, hamster, and mouse when given by gavage.
Environmental Health Perspectives, 30:105-113.
GS0104076 Loesser, E. 1969: "Bay 15 922. Generation Study of Rats,"
by Dr. E. Loser, Farbenfabriken Bayer AG Institut fur
Toxikologie, Wupperfal-Elberfeld (Report No. 1195, January
23, 1969). Ace. No. 244915 (Mobay Report no. 25855, March
24, 1981).
GS0104077 Shirasu, Y., Moriya, M. and Koyashiki, R. 1983. Mobay Report
No. 69367: "Trichlorfon. Mutagenicity Test on Bacterial Systems,"
Institute of Environmental Toxicology (Japan), October 30,
1979. Ace. No. 249535.
GS0104078 SRI (1980a) An Evaluation of the Effect of Trichlorphon on
Sister Chrcmatid Exchange frequencies in cultured Chinese
hamster ovary cells. Prepared for: Environmental Protection
Agency, Research Triangle Park, North Carolina 27711. SRI
Project LSU-7558.
GS0104079 SRI (1980c) In Vitro Detection of Mitotic Crossing-Over,
Mitotic Gene Conversation, and Reverse Mutation with S.
Cerevisiae D7 for Seven Pesticides. EPA Contracts Management
Division (MD-33), Attention: NCCM-6, Research Triangle Park,
North Carolina 27711. Contract No. 68-02-2947, SRI Project
LSU-7558-20.
GS0104080 Chemagro Corp. (1977) Aerobic soil metabolism study, Report
no. 32365; Ace. No. 230752.
GS0104081 Johnson, W., and Finley, M., (1980) Handbook of acute toxicity
of chemicals to fish and wildlife invertebrates. U.S. Fish
and Wildlife Service Pub. No. 137. Washington, D.C.
136
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TT-3.
FIFKA SECTION 3(C)(2)(B) SUMMARY SHEET
EPA
PRODUCT NAME
APPLICANT'S NAME
DATE GUIDANCE DOCUMENT ISSUED
With respect to the requirement to tubmit "aer»eric"diti imposed by the FIFRA section 3(C)12)(B) notice contained in the referenced
Guidance Document. I am responding in the following manner:
01. I will submit data in • timely manner to satisfy the following requirement!. I! the ten procedures I will UK deviate from (or are not
specified in) the Rep'mnrtion Guidelines or the Protocols contained in the Reports of Expert Groups to the Chemicals Group. OE CD
K- Chemicals Testing Programme, I enclose the protocols that I will us: . *
O 2. I have entered into an agreement with one or more other registrants under FIFRA section 3(C)l2)(B)(ii) to satisfy the following dau
requirements. The testi, and any required protocols, will be submitted to EPA fay:
NAME OF OTHER REGISTRANT
O 3. I enclose a completed "Certification of Attempt to Enter Into an Agreement with Other Registrants for Development of Date" with
respect to the following data requirement!:
O 4. I request that you amend my registration by deleting the following uses (this option is not available to applicants for new products):
O 5. I request voluntary cancellation of the registration of this product. (This option is not available to applicants for new products.)
REGISTRANT'S AUTHORIZED REPRESENTATIVE
SIGNATURE
DATE
EPA Form 8580-1 (10-62)
137
-------
Appendix 11-3
OMB
CERTIFICATION OF ATTEMPT TO ENTER
INTO AN AGREEMENT WITH OTHER REGISTRANTS
(To 9t»l/fy. emHyALL lour ttmt) *OR DE VE LOfMENT OF DATA
1 . 1 am duly authorized to raprtsent the following firm(s) who »re subject to the require
cfncnts of •Notice under FIFRA Section 8(c)(2)(B) contained in* Guidance Document
" to submit data concerning the active ingredient:
NAME Or FIRM
- •-• ...
• -
GUIDANCE DOCUMENT DATE
ACTIVE INGREDIENT
€f A COMPANY NUMBE R
...
1
•
(This firm or group of firms is referred to below as "my firm".!
2. My firm b willing to develop and submit the data as required by that Notice, if necessary. However, tny firm would prefer to erne:
into an agreement with one or more other registrants to develop jointly, or to share in the cost of developing, the following require*
hems or data:
My firm has offered in writing to anter into such an agreement Copies ef the off en an anachid.That offer wu irrevocable and included an offer to fc
*ound fey an arbitration decision under FIFRA Section 3U)l2)|B)liii) if final agreement on all terms could not to reched otherwise This offer wts mid
1» tht following firm(s) en the following dated):
*IAME OF FIRM
DATE OF OFFER ''
. • ,'
However, none of those iirmU) eccepteti my offer.
4. My firm requens that EPA not suspend the registration(s) of my firm's product(s), if any of the firms named in paragraph (3) fibtr.
'have agreed to submit the data lined in paragraph (2) above in accordance with the Notice. I understand EPA will promptly infon
me whether my firm must tubmh data to avoid suspension of its registration(s) under FIFRA Section 3(c)(2)(B). (This staiemei
does not apply to applicants for new products.) I give EPA permission to disclose this statement upon request.
rrrco NAME
SIGNATURE
DATE
-------
Appendix III-l
PRODUCT SPECIFIC DATA REPORT
EPA Registration No. Guidance Document for
Date
Registration
Guideline No.
§158.20
PRODUCT
CHEMISTRY
61-1
61-2
61-3
62-1
62-2
62-3
63-2
63-3
63-4
63-5
63-6
63-7
63-8
63-9
63-10
63-11
63-12
63-13
63-14
63-15
63-16
63-17
63-18
63-19
Name of Test
Identity of
ingredients
Statement of
composition
Discussion of
formation of
ingredients
Preliminary
analysis
Certification of
limits
Analytical methods
for enforcement
limits
Color
Physical state
Odor
Melting point
Boiling point
Density, bulk-
density, or
specific gravity
Solubility
Vapor pressure
Dissociation
constant
Octanol/water
partition
coefficient
PH
Stability
Oxidizing/reducing
reaction
Flammability
Explodability
Storage stability
Viscosity
Miscibility
Test not
required
for my
product
listed
above
( check
below)
I am complying with
data requirements by
Citing MRID#
Submit-
ting
Data
(At-
tached)
, ^•".•('
(For EPA Use Only)
Accession Numbers
Assigned
139
-------
Appendix III-l (Continued)
PRODUCT SPECIFIC DATA REPORT
EPA Registration No. Guidance Document for_
Date
63-20
63-21
§158.135
TOXICOLOGY
81-1
81-2
81-3
81-4
81-5
81-6
Corrosion
characteristics
Dielectric break-
down voltage
Acute oral LD-50,
rat
Acute dermal
LD-50
Acute inhalation,
LC-50 rat
Primary eye
irritation, rabbit
Primary dermal
irritation
Dermal sensitiza-
tion
140
-------
PflECAUTONAAV STATEMENTS
HOARDS TO HUMANS
(t DOMESTIC ANIMALS)
OANQER
ENVftONMENTAL HAZARDS
PHY8CAL (M CHCMCAL
HAZARDS
n* iMMai •* MB* IM
*• • www MB
W-€MtWV STATfMtNT
STORAGE AND
DISPOSAL
RESTRICTED USE
PESTICIDE
for retifl tile to tnd ott only by CtrtlMH Ap
or pcnoni tinder th«1r tftrtet tuptrvldon md only for
thoif OKI covered by th* Certified Hppllctton Certifi-
cation.
PRODUCT
NAME
ACTWE MOREDCNT:
tIERT MOREOCNTS.
TOTAL:
10000*
TH8 PRODUCT CONTAM3 IBS Of ft* GALLON
KEEP OUT OF REACH OF CHILDREN
DANGER
STATtMCNT OF PflACTBAL TREATMCNT
rsw ALLOW
r MHAUD:
rONBKN:
r M ETCS :
SEC am PANEL row
STATEMCNTS
MFOBv:
TOWN. STATE:
SPESTARLBHMENT NO
EPA nEOtSTHATtON NO.
NET CONTENTS:
CROP:
CHOP:
CHOP:
CHOP:
WARRANTY STATEMENT
•a
X)
§
Ou
VH
<
I
-------
to
!
!•
HA;Anus to HUMANS
II OUMISIC
ENVinONMCNf Al HA/Anns
MA7AROS
omictoNS ron use
CfNflAt ClASSlflCAflOH
i h • «MMon « FMirtf k» to
M pwdtict n • nmrar
nc INIHV
I*
STORAGE AND
DISPOSAL
OISPOSAI
CHOP
PRODUCT
NAME
AC I'VE
tQIAl
(MIS rnoouci CONTAINS IDS of
10000%
KEEP OUT OF REACH OF Cf IILDREN
CAUTION
SIATCMENT OF PRACICAl
* SWAIIOWEO:
* MHAICO =
r ON SKH
V NIYtS =
SEE SCf PANfl ron AODfTONAl rnECAUUCVMRT SIA1EMEIITS
MfQ BY
y~M 'OWN
CSrABllSMMENf NO
EPA I
Nil CONlEHIS:
to
CROP
cnor
CHOP'
WAnnANrVStAtCMENI
-------
APPENDIX rv-2
LABELING REQUIREMENTS OF THE FIFRA, AS AMENDED (REFER TO THE SAMPLE LABELS FOLLOWING)
ITEM
1
2
3
4
5
6A
6B
7
7A
7B
LA?EL ELEMENT
Product name
Company name
and address
Net contents
EPA Est. No.
EPA Reg. No.
\
Ingredients
statement
'?.
Pounds/gallon
statement
*• • i
Front panel
precautionary
statements
Keep Out of Reach
of Children
(Child hazard
warning)
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
All products
All products
Liquid products
where, dosage
giverfas Ibs.
ai/unit area
All products
All products
All products
PLACEMENT
REQUIRED
Front panel
None
None
None
None
Front panel
Front panel
Front panel
Front panel
Front panel
ON LABEL
PREFERRED
Center front
panel
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel,
immediately
before or
following
Reg. No.
Immediately
following
product name
Directly below
the main
ingredients
statement
Above signal
word
Immediately
below child
hazard
warning
COMMENTS
If registrant is not the producer, mupt-
be qualified by "Packed for . . .,"
"Distributed by. . .," etc.
May be in metric units in addition to
U.S. units
Must be in similar type si7e and run
^parallel to other type.
May appear on the container instead of
the label.
Text must run parallel with other tevt-
on the panel.
All front panel precautionary Ptateinont-p
must be grouped together, preferably
blocked.
Note type size requirement- P.
Note type size requirement P.
-------
APPKNDIX TV-2 (CTPP tinnerl)
ITEM
7C
7D
7E
8
8A
8B
LABEL ELEMENT
Skull & cross-
bones and word
POISON (in red)
Statement of
practical
treatment
Referral
statement
Side/back panel
precautionary
statements
Hazards to
humans and
domestic
animals
Environmental
hazards
APPLICABILITY
OF REQUIREMENT
All products
which are Cat-
egory I based
on oral, der-
mal, or inhala-
tion toxicity
All products
in Categories
I, II, and III
All products
where pre-
cautionary
labeling
appears on
other than
front jpanel.
All products
All products
in Categories
I, II, and III
All products
PLACEMENT
REQUIRED
Front panel
Category I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped with
side panel
precautionary
statements.
Front panel
None
None
None
ON LABEL
PREFERRED
Both in close
proximity to
signal word
Front panel
for all.
Top or side
of back panel
preceding
directions
for use
Same as above
Same as above
COMMENTS
Must be grouped under the headings in
8A, 8B, and 8C? preferably blocked.
Must be preceded by appropriate signal
word.
Environmental hazards include bee
caution where applicable.
1 A A
-------
APPENDIX W-2
ITEM
8C
9A
9C
10A
IOC
10D
U.S.
LABEL ELEMENT
Physical or
chemical
hazards
Restricted
block
Misuse
statement
Re-entry
statement
,
-------
Appendix IV-3
PHYSICAL-CHEMICAL HAZARDS
Criteria
I. Pressurized Containers
A. Flashpoint at or below
20°F; or if there is a
flashback at any valve
opening.
B. Flashpoint above 20°F
and not over 80°F; or
if the flame extension
is more than 18 inches
long at a distance of
6 inches from the
valve opening.
C. ALL OTHER PRESSURIZED
CONTAINERS
II. Non-Pressurized Containers
A. Flashpoint at or below
20°F.
B. Flashpoint above 20°F
and over 80°F.
C. Flashpoint over 80°F
and not over 150°F.
D. Flashpoint above
150°F.
Required Label Statement
Extremely flammable.
Contents under pressure.
Keep away from fire, sparks,
and heated surfaces. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame. Do
not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Contents under pressure.
Do not use or store near
heat or open flame. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Extremely flammable. Keep
away from fire, sparks, and
heated surfaces.
Flammable. Keep away from
heat and open flame.
Do not use or store near
heat and open flame.
None required.
146
-------
Appendix IV-5
STORAGE AND DISPOSAL INSTRUCTIONS FOR PESTICIDES
All products are required to bear specific label instructions
about storage and disposal. Storage and disposal instructions
must be grouped together in the directions for use portion of
the label under the heading STORAGE AND DISPOSAL. Products
intended solely for domestic use need not include the heading
"STORAGE AND DISPOSAL." The STORAGE AND DISPOSAL heading
must appear in the minimum type size listed below:
1 |Required type size |
(Size of label | for the heading j
(front panel in j STORAGE AND DISPOSAL |
square inches | (all capitals)
10 and under 6 point
Above 10 to 15 8 point
Above 15 to 30 10 point
Over 30 12 point
Storage and disposal instructions must be set apart and
clearly distinguishable from other directions for use.
Blocking storage and disposal statements with a solid line is
suggested as a means of increasing their prominence.
A. Storage Instructions;
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed,
Each registrant must develop his own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, Jjeat, sunlight,
friction, or contaminating substances or media.
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
while opening or closing container.
147
-------
Appendix IV-5
(continued)
4. Instructions on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been
spilled, and precautions to minimize exposure if damage occurs.
5. General precautions concerning locked storage, storage in
original container only, and separation of pesticides
during storage to prevent cross-contamination of other
pesticides, fertilizer, food, and feed.
6. General storage instructions for household products should
emphasize storage in original container and placement in
locked storage areas.
B. Pesticide Disposal Instructions;
The label of all products, except those intended solely for
domestic use, must bear explicit instructions about pesticide
disposal. The statements listed below contain the exact wording
that must appear on the label of these products:
1. The labels of all products, except domestic use, must
contain the statement, "Do not contaminate water, food,
or feed by storage or disposal."
2. Except those products intended solely for domestic use,
the labels of all products that contain active ingredients
appearing on the "Acutely Hazardous" Commercial Pesticide
Products List (RCRA "E" List) at the end of this appendix
or are assigned to Toxicity Category I on the basis of
oral or dermal toxicity, skin or eye irritation potential,
or Toxicity Category I or II on the basis of acute inhala-
tion toxicity must bear the following pesticide disposal
statement:
"Pesticide wastes are acutely hazardous. Improper dis-
posal of excess pesticide, spray mixture, or rinsate is
a violation of Federal Law. If these wastes cannot be
disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control
Agency, or the Hazardous Waste representative at the
nearest EPA Regional Office for guidance."vt.
The labels of all products, except those intended for
domestic use, containing active or inert ingredients
that appear on the "Toxic" Commercial Pesticide Products
List (RCRA "F" List) at the end of this appendix or
presently meet any of the criteria in Subpart C, 40 CFR
261 for a hazardous waste must bear the following pesticide
disposal statement:
148
-------
Appendix IV-5
(continued)
"Pesticide wastes are toxic. Improper disposal of excess
pesticide, spray mixture, or rinsate is a violation of
Federal Law. If these wastes cannot be disposed of by
use according to label instructions, contact your State
Pesticide or Environmental Control Agency, or the Hazardous
Waste representative at the nearest EPA Regional Office
for guidance."
Labels for all other products, except those intended for
domestic use, must bear the following pesticide disposal
statement:
"Wastes resulting from the use of this product may be
disposed of on site or at an approved waste disposal
facility."
3. Products intended for domestic use only must bear the
following disposal statement: "Securely wrap original
container in several layers of newspaper and discard in
trash."
C. Container Disposal Instructions
The label of each product must bear container disposal
instructions appropriate to the type of container.
1. All products intended for domestic use must bear one
of the following container disposal statements:
Container Type
Statement
Non-aerosol products
(bottles, cans, jars)
Non-aerosol products
(bags)
Aerosol products
Do not reuse container (bottle, can, jar).
Rinse thoroughly before discarding in trash.
Do not reuse bag. Discard bag in trash.
Replace cap and discard containers in
trash. Do not incinerate or puncture.
2. The labels for all other products must bear container disposal
instructions, based on container type, listed below:
Container Type
Statement.
Metal
containers
(non-aerosol)
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
authorities.
Plastic containers
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay out of smoke.
Glass containers
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
149
-------
Container Type
Appendix IV-5
(continued)
Statement
Fiber drums
with liners
Paper and
plastic bags
Compressed gas
cylinders
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reusedl, dispose of in the same manner.
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Return empty cylinder for reuse (or
similar wording).
^Manufacturer may replace this phrase with one indicating whether
and how fiber drum may be reused.
2. The labels for all other products must bear container
disposal instructions, based on container type, listed
on the first page of this Appendix.
150
-------
Appendix IV-5
(continued)
Pesticides that are hazardous wastes under 40 CFR 261.33(e) and (f)
when discarded.
"Acutely Hazardous" Commercial Pesticides (RCRA "E" List)
Active Ingredients, (no inerts);
Acrolein
Aldicarb
Aldrin
Allyl alcohol
Aluminum phosphide
4-Aminopyridine
Arsenic acid
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroaniline
Cyanides (soluble cyanide salts, not specified elsewere)
Cyanogen chloride
2-Cyclohexyl-4,6-dinitrophenol
Dieldrin
0,0-Diethyl S-[2-ethylthio)ethyl] phosphorodithioate
(disulfoton, Di-Syston)
0,0-Diethyl 0-pyrazinyl phosphorothioate (Zinophos)
Dimethoate
0,0-Dimethyl 0-p-nitrophenyl phosphorothioate (methyl parathion)
4,6-Dinitro-o-cresol and salts
4,6-Dinitro-o-cyclohexylphenol
2,4 Dinitrophenol
Dinoseb
Endosulfan
Endothall
Endrin
Famphur
Fluoroacetamide
Heptachlor
Hexanethyl tetraphosphate
Hydrocyanic acid
Hydrogen cyanide
Methomy1
alpha-Naphthylthiourea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide (OMPA, schradan)
Parathion
151
-------
Appendix IV-5
(continued)
"Acutely Hazardous" Commercial Pesticides (RCRA "E" List)
Active Ingredients continued;
Phenylmercuric acetate (PMA)
Phorate
Potassium cyanide
Propargyl alcohol
Sodium azide
Sodium cyanide
Sodium fluoroacetate
Strychnine and salts
0,0,0,0-Tetraethyl dithiopyrophosphate (sulfotepp)
Tetraethyl pyrophosphate
Thallium sulfate
Thiofanox
Toxaphene
Warfarin
Zinc phosphide
There are currently no inert ingredients for commercial pesticides
on the "Acutely Hazardous" List (RCRA "E" List).
152
-------
Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA "F" List)
Active Ingredients;
Acetone
Acrylonitrile
Amitrole
Benzene
Bis(2-ethylhexyl)pthalate
Cacodylic acid
Carbon tetrachloride
Chloral (hydrate)
Chlordane (technical)
Chlorobenzene
4-Chloro-m-cresol
Chloroform
o-Chlorophenol
4-Chloro-o-toluidine hydrochloride
Creosote
Cresylic acid
Cyclohexane
Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[c ,d]-pentalen-2-one
(kepone, chlordecone)
l,2-Dibromo-3-chloropropane (DBCP)
Dibutyl phthalate
S-3,3-(Dichloroallyl diisopropylthiocarbamate (diallate, Avadex)
o-DiChlorobenzene
p-Dichlorobenzene
Dichlorodifluoromethane (Freon 12®)
3,5-Dichloro-N-(1,l-dimethyl-2-propynyl) benzamide (pronaroide,Kerb)
Dichloro diphenyl dichloroethane (DDD)
Dichloro diphenyl trichloroethane (DDT)
Dichlorethyl ether
2,4-Dichlorophenoxyacetic, esters and salts (2,4-D)
1,2-Dichloropropane
1,3-Dichloropropane (Telone)
Dimethyl phthalate
Ethyl acetate
Ethyl 4 ,4'-dichlorobenzilate (chlorobenzilate)
Ethylene dibromide (EDB)
Ethylene dichloride
Ethylene oxide
Formaldehyde
Furfural
Hexachlorobenzene
Hexachlorocyclopentadiene
Hexachloroethane
Hydrofluoric acid
153
-------
Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA "F" List)
Active Ingredients;
Isobutyl alcohol
Lead acetate
Lindane
Maleic hydrazide
Mercury
Methyl alcohol
Methyl bromide
Methyl chloride
2,2'-Methylenebis (3,4,6-trichlorophenol) (hexachlorophene)
Methylene chloride
Methyl ethyl ketone
4-Methyl-2-pentanone (methyl isobutyl ketone)
Naphthalene
Nitrobenzene
p-Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentaclorophenol
Phenol
Phosphorodithioic acid, 0,0-diethyl, methyl ester
Propylene dichloride
Pyridine
Resorcinol
Safrole
Selenium disulfide
Silvex
1,2,4,5-Tetrachlorobenzene
1,1,2,2-Tetrachloroethane
Tetrachloroethylene
2 ,3 ,4 ,6-Tetrachlorophenol
Thiram
Toluene
1,1,1-Trichloroethane
Trichloroethylene
Trichloromonofluoromethane (Freon 11 )
2 ,4,5-Trichlorophenol
2,4,6-Trichlorophenol
2,4,5-Trichlorophenoxyacetic acid (2,4,5-T)
Xylene
154
-------
Appendix IV-5
(continued)
"Toxic" Commercial Pesticide Products (RCRA "F" List)
Inert Ingredients;
Acetone
Acetonitrile
Acetophenone
Acrylic acid
Aniline
Benzene
Chlorobenzene
Chloroform
Cyclohexane
Cyclohexanone
Dichlorodifluororoethane (Freon ,12®)
Diethyl phthalate
Dimethylamine
Dimethyl phthalate
1,4-Dioxane
Ethylene oxide
Formaldehyde
Formic acid
Isobutyl alcohol
Meleic anhydride
Methyl alcohol (methanol)
Methyl ethyl ketone
Methyl methacrylate
Naphthalene
Saccharin and salts
Thiourea
Toluene
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Trichlorofluoromethane (Freon 11®)
Vinyl chloride
Xylene
155
-------
lutio
,. and Mfety of MM fonwtttated
I-UM product, may not consider any
date M supporting MM application.
except tlM following date:
(I) The date MM applicant h»» eub-
nOtted to EPA under paragraph (bV of
this section;
(1) Other date pertaining to MM
Mfety of the product's active Ingredi-
ents, rather than to the Mfety of MM
end UM product; and
II) Existing tolerance*, food additive
regulation*, exemption*, and other
dearances Issued under UM Federal
Food. Drug, and Cosmetic Ad. ,
(e) If UM applicant knows MM! any
Item of date he aubmltted under M»to
•ectlon WM generated by (or at MM •*>
pense of) another person who original-
ly aubmltted the date |O BPA (or Its
predecessor, USD A) on or after Janu-
ary 1,1910. to support an application
for registration, experimental UM
permit, or amendment adding a new
use to an cabling registration, or for
rereglstrallon (untoM Mi* applicant
and the original date aubndMW hay*
reached written agreement on MM
amount and MM term* of payment of
any compensation, thai may bo.pay-
able under , FIFBA 'Motion
. KoKlMDNU) with regard to approval
of the application). MM applicant chall
submit to EPA a atatement Miat bo
hM fumtohed to each aueh tdenMfted
original data •ubmlttcn • .
(I) A notification of th* appttcantV
Intent to apply for registration. Indutf-
Ing the proposed produd name;
fa) An offer to pay MM penon COM-
penMUon. with regard to MM approval
of th* application, to MM extent ro- ,
quired by FIFRA •ecMonii McMINp)
.*nd KeMiKDh
(I) An Identification of MM ftonKcl
of data to which the of far appltos;
(4) An offer to commence negotia-
tions to ascertain MM amount and
term* of compensation to be paid; and
(•) The applicant'* name, address*
and telephone number.
(f> if the appllcant'a produd con-
tains any active Ingredient ether M»sn
thoM that are present solely becauM
of the Incorporation Into the product,
dtirlng formulation, of one or mor*
other registered pesticide product*
purchased from another producer.
then the applicant shall also comply
HIM 40— frolecltcp «.f fnvlr*na«*a|
with f IMJ-I M to such active Ingredi-
ent, and the application shall contain
an acknowledgment that for purposes.
of PIPRA section »(oK|MD) the appli-
cation relies on (and any resulting reg-
istration should be regarded M If U
were based on the Administrator's con-
alderallon of) the following data:
(|| All data aubmltted or specifically
cited by the applicant In support of
MM registration; and
CJ> Bach other Item of 0>l* In MI*
'Agency's files which:
' (I) Concerns th* properties or effects,
Of any such act|ve Ingredient; and .
(II) I* one of the types of data, that
BPA. would require to be submitted for
adentlflo review by BPA If the apnli-
cant sought the InIMM registration
Under PIFBA Section KcMI) of a
product with composition and Intend-
ed uses Identical to MIOM proposed for
the applicant's product under the
data requirement* In effect on Ins
data EPA approve* the applicant'*
prcMn} application.
APPENDIX V-l
ivfreiMMNtal rr*f ocl>n A*j*ncjr
1« 10
VJMXIM *!•**>
(a) CtofMfwl-41) Orafmfi ol 0N)
totol Every pesUekw product* ahal)
bear a label containing MM tnforma-
Mon specified by the Act and the regu-
laMons bi this Tart. The content*, of a
libel must show dearly and promi-
nently the following:
(I) The name, brand, or tredem«r»
under which th* product h) sold upre-
aoribed to paragraph (b) of thb seo-
(U) Tho name and address of MM
producer, registrant, or peraon for
whom produced M prescribed In para-
graph (e) of this section;
(111) Tho net content* M prescribed
In paragraph (d) of this section:
(!*) The product registration
number M prescribed In paragraph (e)
of this section;
(V) The producing establishment
'number M prescribed In paragraph (f I
of this section;
(vl) An Ingredient atatement M pra-
aerlbei) |n paragraph (g) of this sec-
tion;
(vlll Warning or precautionary state-
ments M prescribed In, paragraph such term* M to render It
likely to be read and understood by
the ordinary Individual under custom-
ary conditions of purchaM and use,
(l|> All required label text must: \
(A) Be Ml In • point or larger type;
(B) Appear on a clear contrasllng
background; and
(C) Not be obscured or crowded.
(|) f+nammot to bt usedl All required
label or labeling text «hal| appear la
the English language. However, th*
Agency may require or the applicant
may propoM additional text In other
languages M to considered neceaaary to
protect MI* public. When additional
(axt In another language to necessary.
all labeling requirement* will be ap-
plied equally to both the English and.
other language versions of the label-
ing.. - . -; •.-.•:.'
(4) JVactwMftf o/ taoef-d) CtourmL
'The Uoddiall appear on or be secure-
ly attached to MM Immediate contain-
er of MM pesticide product. For pur-
poses of this Section, and MM Aito-
brand.« provision* Of |no Ad. "M-
furely attacheoT slisll mean MuU •
label can reasonably be expected to
remain affixed during the foreseeable
conditions and period ol UM. If the lift-
mediate container to enclosed within a
*r«PP«r or ouUlde container through
which M» label cannot be dearly read.
Ihe |abe| must also be securely at-
tached to aueh outside wrapper or con-
tainer; If It |a a part of |he package M
euslomarfly distributed or sold.
(Ill fan* cart and other out* con-
faliier*-(A) rraniporfadon. While a
pesticide product to |n transit, the ap-
propriate provisions of <• CPU Parts
110-IM. concerning the transportation
of hasardous malerlato. and specifical-
ly MIOM provtolons concerning the la-
beling, marking and placarding of has-
ardous materials and the vehicles car-
rying them, define Ihe basic Federal
requirement*. In addition, when any
registered pesticide product to trans-
ported in a tank car. tank truck or
other mobile or portable bulk iwnlaln-
er. a copy of tlie accepted label must
be attached to the snipping papers.
»nd left with the consignee at Itie time
of delivery.
(B) Storage. Wtwn pesticide prod-
uct* are stored hi bulk container*.
Whether mobile or stationary, which
remain In the custody of HM user, a
copy of the label of labeling. Including
all appropriate directions for UM. shall
be securely attached to the container
m the Immediate vicinity of the dis-
charge control valve.
(I) fafM or mlifearflnr »latem«nU
Pursuant to aectlon KqK| MA) of the
Ad. » pesticide or a device declared
subject to the Act pursuant to 1161 la.
|* mtobranded If lla labellitg to lalse or
misleading In any particular HNjudlng
both pesticldBl and nonpeallcltlal
ctoJma, Examples of statements or reu-
reMntatlons In MM labeling whWi con-
stitute mtobrandlng Include:
(|) A fake or mUleadlng atatemeiH
concerning the composition of the
product;
(II) A fatoe or misleading statement
concerning UM effectiveness of the
product M a pesticide or device; -
(111) A fatoe or misleading statement
about th* value of the product for
purposes other than M a peatlclde or
device;
(Iv) A fatoe or misleading comparison
with other pesticides or devices;
(y) Any alalement directly or Indi-
rectly Implying that the pesticide or
device b recommended or endorsed by
any agency of the Pedersl Uovern-
ment;
(vl) The name of a peslldde which
contains two or more principal active
Ingredients If the name suggests one
or more but not all such principal
active Ingredients even l|iough the
name* of the other Ingredient < are
slated elsewhere In the labeling-;
156
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I
IIM.IO
(vll) A true statement used In such a
way M to clve a fabe or misleading Im-
pression io the purchaser;
(vlll) Label disclaimer* which negate
or detract from labeling •tatemenU re-
quired under the Act and, these ref u|a-
llona;
"pollution approved"
(g) Final printed laoeffsjgt (I) Bxeept
M provided lit paragraph (aXCMIU of
Into aecllon. final printed, labeling
muat be aubmltted and accepted prior
to registration. However, final printed
labeling need not be aubmltted until
draft label texts, have been proyblon-
elly accepted by the Agency.
Ill) Clearly legible reprodneUora or
photo reduction* will be accepted for
uniuual labela tucli M Ihoao eQk-
acreened directly onto glaaa or metal
container* or large bag or drum labela.
Such reproduction* must be of micro-
film reproduction quality.
pose a
hazard to niaii or the environment.
(h) Warning* and precautionary
n/
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IhoM required on MM Irani panel of
the labeling and ihoM which may
appear elsewhere. Specific requlre-
menU concerning content, placement.
type size, and prominence ere given
below.
(I) Jteaufred front panel sfaiezMnfa.
With the exception of the child
DUo 4*-fr.f.t!M of favlreemoHf
hazard warning statement, the text re-
quired on MM front pane) of the label
|s determined by the Toxlclty Catego-
ry of the pesticide. The category Is M-
•lined on the bub of the highest
hazard shown by any of the Indlcatqra
In the table below:
' •
l*»M*Mu*«SM fmSMSlMSMS - rtMl.OMftmM.OM. OiMtaf MM BI.CO*.
M/W
(|) ffHtnaii ftasanf sfeiiajf
ifyCateporyf. All pesticide prod-
meeting the criteria- of Toxlclty
gory I shall bear on the from;
ucU
Category
panel the signal word "Danger." In ad-
dition If the product wee assigned to
Toilclly Category I on the basis of Its
oral. Inhalation or dermal loxlclty (as
distinct from skin and eye local ef-
fects) the word "Poison" shall appear
fat red on a background of dUtlitctly
contrasting color and MM skull and
croMbones shall appear In Immediate
proximity to the word "poison."
-------
lions |o avo|d potential accident.
Injury or damage.. Biample* of the
hazard statement* and |be circum-
stances under which they ere required
follow:
(At If a pesticide Intended, for out-
door UM contain* MI active Ingredient
with a mammalian acute oral |4X» of
100 or leu. thestatement Thto>esU-
elite U Toilo lo Wildlife* Is required-
(Bl If a pesticide Intended for out-
door UM contains an active Ingredient
vlth a lUh acute UX* of I ppm or less.
the statement Thto Pesticide to Toxlo
lo Hsh" to required.
(0 If a peitkMo Intended for out-
door UM contains an aotlf • Ingredient
with an avlan acute oral UX. of 100
mg/kg or less, or a subacute dietary
I A. of 100 ppm or lea. the statement
'This Pesticide to Toilo to
required. *
flHo 10-frotecHoN of f nvlr.n-«..|
If either accident hUtory or f|eld
studies demonstrate that use of tho
pestlcfde may result In fatality to
plrds. fish or mammals, the statement
Hrttls pesticide to extremely toi|o. to
wildlife iflshT to required.
(K) For uses Involving foliar applica-
tion to agricultural crops, forests, or
shade trees, or for mosquito abate-
ment treatments, pesticides tox|o to
pollinating Insects fiust bear approprl-
•,!•*•».
(I) OtmlloM jbr
— 41)
Ctoiwral
o/ 4lr« UN'- •
Jtecepffows fa r*att|f*>W*f for
direction /or HM-IA) Petelled direc-
tions for use may be omitted from la-
beling of pesticides, which, are Intended
for UM only by manufacturer* °' prod- {
ucla other than pesticide products In
|helr regular manufacturing processes.
provided that:
1 f J) The label clearly shows (hat the
product to intended for UM only hi
manufacturing processes and speclflef
the type(s) of products Involved.
(I) Adequate Information such M
technical data sheets or bulletins, to
available lo the trade specifying the
type of product Involved and Ite
proper UM In manufacturing process-
es;
14) The product w|l| not «*«• feto
the hands of the general publlo except
after Incorporation Into finished prod-
•"•'•• tnd
The Administrator determine*
••*!»' .ll»»..ll«— «
and effectlveneM of tho product for
pesticide purpoaes;
(I) Ttio |abe| c|early slates that the
l^oducl to Intended for UM only In
manufacturing, formulating, mixing.
Pr repacking for UM aa a pesticide and
•ped'tea Hie type(s) of peullcldi) prod
.,, ...r «».«nnii»M»Mir qeiernunu,
that such dlrecUons are not necessary
to prevent unreasonable advene ef-
fecta on. man or the environment. ,
IB) DeUlled directions for UM. may
be omitted from the labeling of pest|-
rKi* nr.w!...!., i0t Whlch sale to
label elcariy atetea that
u1611 "• tolMtottot
The statement of UM classifica-
tion (is prescribed In 1*110(1) Immedi-
ately under the heading "Directions
for MM."
(II) Immediately below the state-
ment of UM classification, the state-
ment "It to a violation of federal law
to us* this product In a manner Incon-
sistent will) Ite labeling."
IIP) The sltefa) of application, as for
example the crops, annuals, areas, or
objects, to be treated.
• llv) The target pesMa) associated
With each site.
(V) The dosage rate associated with
each alto and peak
(vl).The method of application. In-
cluding Instructions for dilution. If re-
quired, and typeta) of application ap-
paratus or equipment required.
e pesticide has been
applied, meeting the requirements
concerning reentry provided by 40
CPU Part 1YO.
fix) Specific directions concerning
fhe storage and disposal of the pesti-
cide and Ite container, meeting the re-
quirements of |0 CVfl Part loB. These
Instructions sliall be ground and
appear under the heading "Storage
and DlspoM|." Tills |te*dtng muat be
159.'
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APPENDIX V-l
f 142.1 T
t
the saaui alBliBiim staav beyond thoae pmpum tad uses ean-
arrequUad for the. etUld taaard wain- tataed to the- Directions for Use win be
IB* (Se»Tial* la f la&lOfhXIXirU considered a fate or mtalrartlnr state-
Batrtettd. tfar Ctasri/ten.
gftr at**) daattted rncrietad
^tanr statamtx of nsxncctd QM
OB tte
U) fnmt asacf ttatanatt of restrict-
,y' ->BBi7 fortaoa* ttses cprued bytae Cer-
tfoa. Aay tmtfvtd* prodaes for waitir ttftod Apptlcaror'^ eertlflcatlan."' U.
^ nmm^mrm H««^ftyf frt^ ff«»T^| n^^ BOWeTBR OtaBT rmilatflry mUlgtlOPl
otam for rcstricxad on saall. to* •*** latpuacd. toe AdaUalstrator will
ily -.t^^ ma.mnrtin (0 ^^i^.. ^djiftot the appropriate wording- f or thr
tandards* set fft***i to »«*• ntt- ^tatsoa of restriction br resulatloa*
•"** saail. to 'p*|l>^Mi1 as irnni ^^ AdnarttslBC CRavirieiil
. wtta dfitftfest ncfstn^ t luailiiy UUecUoas Aoc. 1. WBc 40 PR sasti. And 21. UTS, u-
OBir* far ccneraL oaets) aad tae otacr •o«adadrat u m 5788. *%*». 3. \srrm
taat^lf a. product aaa tota- re—
srogaiasets). both
^^^^^ ^^^^^A^
lor rvt
ihifl tosnaja«cto
CD uro Ifte C3to
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