EPA-450/3-77-008e
October 1976
      PRELIMINARY SCORING
      OF SELECTED ORGANIC
             AIR POLLUTANTS
               APPENDIX IV -
  CHEMISTRY, PRODUCTION,
               AND TOXICITY
               OF CHEMICALS
                O THROUGH Z
  U.S. ENVIRONMENTAL PROTECTION AGENCY
      Office of Air and Waste Management
   Office of Air Quality Planning and Standards
   Research Triangle Park, North Carolina 27711

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                                EPA-450/3-77-008e

          PRELIMINARY SCORING
OF SELECTED ORGANIC AIR POLLUTANTS
                APPENDIX IV -
         CHEMISTRY, PRODUCTION,
                AND TOXICITY
                OF CHEMICALS
                O THROUGH Z
                        by

                 J. Dorigan, B. Fuller and R. Duffy

                   The Mitre Corporation
                     Metrek Division
                   Westgate Research Park
                   McLean, Virginia 22101

                   Contract No. 68-02-1495

                     Project No. 077L


                EPA Project Officer: David R. Patrick


                     Prepared for

               ENVIRONMENTAL PROTECTION AGENCY
                Office of Air and Waste Management
               Office of Air Quality Planning and Standards
               Research Triangle Park, North Carolina 27711

                     October 1976

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                           PREFACE

     A program is being developed by the Emission Standards and
Engineering Division of the U.S.  Environmental  Protection Agency to
determine the extent and environmental effects  of atmospheric industrial
emissions of synthetic organic chemicals.  As part of the initial effort,
EPA requested that the MITRE Corporation, METREK Division, devise a
system for identifying those chemicals that may be released to the
atmosphere from chemical manufacturing plants and whose health effects
have been documented.  To address this need, three general categories of
information for each compound to be evaluated were deemed directly
relevant:
     (1) the quantity of the compound produced;
     (2) the potential for atmospheric release from chemical manu-
         facturing plants, and
     (3) the toxicological effects of the compounds.
The results of this study are presented in the accompanying report
"Preliminary Scoring of Organic Air Pollutants."
     The following dossiers were prepared for each of the 637 compounds
under consideration in an attempt to collate the pertinent data for
subsequent evaluation.

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                         TABLE OF CONTENTS
Octyl alcohol                                                 AIV-2
Octyl decyl phthalate                                         AIV-4
Octylphenol                                                   AIV-6
Oxalic acid                                                   AIV-8
Paraldehyde                                                   AIV-10
Paraquat                                                      AIV-12
PCNB                                                          AIV-14
PCP                                                           AIV-16
Pentaerythritol                                               AIV-18
Pentane                                                       AIV-20
Pentylene                                                     AIV-22
Perchloroethylene                                             AIV-24
Perchloromethyl mercaptan                                     AIV-26
o-Phenetidine                                                 AIV-28
p-Phenetidine                                                 AIV-30
Phenol                                                        AIV-32
Phenothiazine                                                 AIV-34
o-Phenylenediamine                                            AIV-36
p-PHenylenediamine                                            AIV-38
Phenylhydrazine                                               AIV-40
Phosgene                                                      AIV-42
Phthalic anhydride                                            AIV-44
Phthalimide                                                   AIV-46
Phthalonitrile                                                AIV-48
Picloram                                                      AIV-50
g-Picoline                                                    AIV-52
a,g-Pinene                                                    AIV-54
Piperazine                                                    AIV-56
Piperonyl butoxide                                            AIV-58
Planavin                                                      AIV-60
Polacrylamide                                                 AIV-62
Polybutenes                                                   AIV-64
Polychlorinated biphenyl                                      AIV-66
Polyethylene and co-polymers                                  AIV-68
Polyethylene glycols                                          AIV-70
Polyethylene glycol chloride                                  AIV-72
Polyethylene terephthalate                                    AIV-74
Polypropylene                                                 AIV-76
Polypropylene glycol                                          AIV-78
Polystyrene                       .                            AIV-80
Polystyrene, thermoplastic resins                             AIV-82
Polytetrafluoroethylene                                       AIV-84
Polyvinyl alcohol                                             AIV-86
Polyvinyl chloride                                            AIV-88

                                 iii

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                   TABLE OF CONTENTS (Continued)
Princep                                                       AIV-90
Propachlor                                                    AIV-92
Propane                                                       AIV-94
Propanil                                                      AIV-96
Propargyl alcohol                                             AIV-98 :
Propazine                                                     AIV-100
Propiolactone                                                 AIV-102
Propionaldehyde                                               AIV-104
Propionic acid                                                AIV-106
Propyl acetate                                                AIV-108
Propyl alcohol                                                AIV-110
Propylamine                                                   AIV-112
Propyl chloride                                               AIV-114
Propylene                                                     AIV-116
Propylene chlorohydrin                                        AIV-118
Propylene glycol          ~                                	AIV-120
Propyleneimine                                                AIV-122
Propylene oxide                                               AIV-124
Pyridine                                                      AIV-126
Randox                                                        AIV-128
Resorcinol                                                    AIV-130
Ronnel                                                        AIV-132
Ruelene                                                       AIV-134
Salicylic acid                                                AIV-136
Silvex                                                        AIV-138
Sodium acetate                                                AIV-140
Sodium benzoate                                               AIV-142
Sodium carboxymethylcellulose                                 AIV-144
Sodium chloroacetate                                          AIV-146
Sodium formate                                                AIV-148
Sodium phenate                                                AIV-150
Sorbic acid                                                   AIV-152
Sorbitol                                                      AIV-154
Styrene monomer                                               AIV-156
Succinic acid                                                 AIV-158
Succinonitrile                                                AIV-160
Sulfanilic acid                                               AIV-162
Sulfolane                                                     AIV-164
Sulfosuccinic, bis (2-ethylhexyl)  ester,  sodium salt          AIV-166
Sutan                                                         AIV-168
TEA                                                           AIV-170
TCA                                                           AIV-172
Terephthalic acid                                             AIV-174
Termik        '""                                              AIV-176
l,l,l:,2-Tetrachloro-2,2-difluoroethane                        AIV-178

                                  iv

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                   TABLE OF CONTENTS (Continued)
I,1,2,2-Tetrachloro-l,2-difluoroethane
Tetrachloronaphthalene
Tetrachlorophthalic anhydride
Tetraethyl lead
Tetrahydrofuran
Tetrahydronaphthalene
Tetrahydrophthalic anhydride
Tetramethylethylenediamine
Tetrainethyl lead
Tetramethyl succinonitrile
Tetranitromethane
Tetrapropylene
Tetryl
Thiuram
o-Tolidine
Toluene
Toluene-2,4-diamine
Toluene diisocyanate
Toluenesulfonamide
o-Toluenesulfonic acid
p-Toluenesulfonic acid
Toluenesulfonyl chloride
m-Toluidine
o-Toluidine
p-Toluidine
Toxaphene
Tributyl phosphate
Trichloroaniline
Trichlorobenzene
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Trichloroethylene
Trichlorofluoromethane
Trichloroisocyanuric acid
Trichloronaphthalene
Trichlorophenoxyacetic acid
Trichloropropane
Trichlorotrifluoroethane
Tricresyl phosphate
Tridecylbenzenesulfonic acid, sodium salt
Triethanolamine
AIV-180
AIV-182
AIV-184
AIV-186
AIV-188
AIV-190
AIV-192
AIV-194
AIV-196
AIV-198
AIV-200
AIV-202
AIV-204
AIV-206
AIV-208
AIV-210
AIV-212
AIV-214
AIV-216
AIV-218
AIV-220
AIV-222
AIV-224
AIV-226
AIV-228
AIV-230
AIV-232
AIV-234
AIV-236
AIV-238
AIV-240
AIV-242
AIV-244
AIV-246
AIV-248
AIV-250
AIV-252
AIV-254
AIV-256
AIV-258
AIV-260

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                    TABLE OF CONTENTS (Concluded)
Triethylamine                                                 AIV-262
Triethylene glycol                                            AIV-264
Triethylene glycol, dimethyl ether                            AIV-266
Triethylene glycol, monomethyl ether                          AIV-268
Trifluralin                                                   AIV-270
Triisobutylene                                                AIV-272
Trimethylamine                                                AIV-274
Trimethylpentanediol                                          AIV-276
Trinitrotoluene                                               AIV-278
Trithion                                                      AIV-280
Urea                                                          AIV-282
Vernam                                                        AIV-284
Vinyl acetate                                                 AIV-286
Vinyl chloride                                                AIV-288
Vinylidene chloride                                           AIV-290
Vinyltoluene                                                  AIV-292
Warfarin                                                      AIV-294
m-Xylene                                                      AIV-296
o-Xylene                                                      AIV-298
p-Xylene                                                      AIV-300
Xylenesulfonic acid, sodium salt                              AIV-302
2,6-Xylenol                                                   AIV-304
3,5-Xylenol                                                   AIV-306
Zinc stearate                                                 AIV-308
Chemical Name Index                                           AIV-310
                                 VI

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                  APPENDIX IV









CHEMISTRY,  PRODUCTION AND TOXICITY OF SELECTED




         SYNTHETIC ORGANIC CHEMICALS
                      AIV-1

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Octyl alcohol
                                     CHEMICAL  NAME
    CAS Number:   1341-41-9

    Chemical Name:    Isooctyl alcohol

    Synonyms:  2-Ethylhexyl alcohol
               2-Ethyl-14iexanol

    Molecular
      Formula:  C8H180
    Structure:    CH2 - CH2 - CH2 - CH2 - CH - CH2OH

                                         CH,,
                                         I
                                         CH,
    Chemical Properties

       Molecular Weight:     130.23

       Vapor Pressure:    0.2 mm at 20°C

       Boiling Point:   18S°C

       Density:  0.8328 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:
Physical State:     Liquid

Vapor Density:     4.49

Melting Point:  -76°C

Solubility:   Insoluble (H2O)
    Environmental Persistence

       BOD:     37% of theoretical

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
          Fire-moderate
                                             AIV-2

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                                                                      Octyl alcohol
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):  15.8
                                TOXICITY DATA

Acute Toxicity              Dosage               Animal              Route
     LD50              1480mg/kg           rat                oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-3

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                                   CHEMICAL  NAME
CAS Number:   119-07-3

Chemical Name:    Phthalic acid, decyl octyl ester

Synonyms:  n-Octyl-n-decyl phthalate
            Decyl octyl ester of phthalic acid
Molecular
  Formula:
Structure:
                          0-C10H21
Chemical Properties

   Molecular Weight:  418.6

   Vapor Pressure:    Negligible at 25°C

   Boiling Point:   239°C at 4 mm

   Density:  0.980 at 20°C/20°C

   Octanol/Water Parti-
     tion Coefficient:
Physical State:  Liquid

Vapor Density:

Melting Point:   -40°C

Solubility:
Environmental Persistence

   BOD:

   Atmospheric Reactivity:   Reacts with oxidizing materials
Safety Hazard:
      Fire-slight
                                           AIV-4

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                                                           Octyl decyl phthalate
                             PRODUCTION DATA

Annual U.S.
 Production:   200xl06lbs.                    Consumption:  200x10  Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:   1-°                               duction Lost:    °-015

Release Rate (million Ibs/yr):  203.0
                                TOXIC ITY DATA

Acute Toxicity              Dosage              Animal               Route
Chronic Toxicity

   U.S. Occupational Standard:




   Carcinogenicity:



   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-5

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Octylphenol
    CAS Number:  27193-28-8

    Chemical Name:    Octylphenol

    Synonyms:   Diisobutylphenol
    Molecular
      Formula:  Ci4H22O
    Structure:
                                     CHEMICAL  NAME
CH,
1  *	
C-CH,
J^	   J
CH3
                                OH
    Chemical Properties

       Molecular Weight:     206.36

       Vapor Pressure:

       Boiling Point:   280 to 283°C

       Density:    °-941 at 24°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
                  Physical State:  Solid

                  Vapor Density:

                  Melting Point:

                  Solubility:  Insoluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-slight
          Disaster hazard—dangerous—toxic fumes-phenol
                                             AIV-6

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                                                                       Octylphenol
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
     LDLo               25 mg/kg            mouse              intraperitoneal
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-7

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Oxalic acid
                                     CHEMICAL NAME
    CAS Number:    144-62-7

    Chemical Name:    Oxalic acid

    Synonyms:  Ethanedioic acid
    Molecular
     Formula:   C2H204
Structure:
                    C - C
            HO
                           O
                           OH
    Chemical Properties

       Molecular Weight:  90.04

       Vapor Pressure:

       Boiling Point:    150°C (sublimes)

       Density:  1.653 (hydrate)

       Octanol/Water Parti-
        tion Coefficient:     -0.78

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
                                                Physical State:     Solid

                                                Vapor Density:

                                                Melting Point:  187°C (anhydrous)

                                                Solubility:   Soluble (H2O)
                                              AIV-8

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                                                                             Oxalic  acid
                               PRODUCTION DATA

Annual U.S.
 Production:  18 x 106 ibs. (1974 estimate)           Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                                       duction  Lost:  0.015

Release Rate (million Ibs/yr):
                                  TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LDL0                700 mg/kg            human             oral
                         lOOOmg/kg      j      dog                oral

Non-lethal Acute Effects:
      Conosion of mouth, esophagus and stomach
      Kidney and liver damage
      Irritation of eyes and upper respiratory tract
      Corneal damage
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 1 mg/m3



   Carcinoganicity:


   Mutagenicity:

   Teratogenicity:                                TLV:    1 mg/m3

   Other Chronic Effects:
      Skin irritation
                                        AIV-9

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Paraldehyde
                                     CHEMICAL NAME
    CAS Number:   123-63-7

    Chemical Name:     2,4,6-Trimethyl-s-trioxane

    Synonyms:   Paraldehyde
                Paia-acetaldehyde

    Molecular
      Formula:   C6H12O3
                        CH3
                     O    O
    Structure:         I     I
                H3C    O    CH3
    Chemical Properties

       Molecular Weight:   132.18                      Physical State:  Liquid

       Vapor Pressure:  25.3 mm at 20°C                Vapor Density: 4.55

       Boiling Point:    124.5°C                        Melting Point:  12.6°C

       Density:  0.9943 at 20°C/4°C                    Solubility:   Slightly soluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:   0.95

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials ,
     Safety Hazard:  Fire-dangerous
                   Explosion-slight
                                             AIV-10

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                                                                         Paraldehyde
                               PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                      duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal              Route
     LDSO               3500mg/kg            dog                oral

Non-lethal Acute Effects:
     Irritation of eyes and mucous membranes
     Dermatitis
     Psychotrophic effects
        TDLo              14 mg/kg           human              oral
                           14 mg/kg           human              intravenous
                           71 mg/kg           human              intramuscular
                           14 mg/kg           human              rectal
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      Neoplasm
        TDj_,0              12gm/kgfora week   mouse              skin
   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-11

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Paraquat
                                      CHEMICAL  NAME
    CAS Number:   1910-42-5

    Chemical Name:    l,l'-Dimethyl-4,4'-bipyridium dichloride

    Synonyms:     Paraquat
                  l,r-Dimethyl-4,4'-dipyiidium salt
    Molecular
      Formula:
  C12H14N2-2C1
Structure:
a(-> CH(+)_
                                               - CH(3+)Cl<->
    Chemical Properties

       Molecular Weight:  257.18

       Vapor Pressure:  non-volatile

       Boiling Point:   Decomposes

       Density:  1.24 to 1.26 at 20°C/20°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
            Susceptible to ultraviolet decomposition
                                    Physical State:     Solid

                                    Vapor Density:

                                    Melting Point:

                                    Solubility:  Infinite
    Safety Hazard:
                                             AIV-12

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                                                                              Paraquat

                               PRODUCTION DATA
Annual U.S.
 Production:   (O, through 1976)                  Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
         LDso            57 mg/kg               rat                 oral
                         80 mg/kg               rat                 oral
                         50 mg/kg               monkey             oral
                         22 mg/kg               guinea pig           oral
         LDi,0           236 mg/kg               man                oral

Non-lethal Acute Effects:
         Lung injury
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:
         TDLo:            6500 fig/kg (6 days)     pregnant rat       intraperitoneal
   Other Chronic Effects:
                                       AIV-13

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PCNB



                                      CHEMICAL  NAME


    CAS Number:   82-68-8

    Chemical Name:   Pentachloronitiobenzene

    Synonyms:   PCNB
                Quintozene terrachlor
                Tritison
    Molecular
      Formula:   C6C15NO2
    Chemical Properties

       Molecular Weight:  295.32                       Physical State:  Solid

       Vapor Pressure:                                 Vapor Density:

       Boiling Point:    328°C (some decomposition)       Melting Point:  144°C

       Density:     1.718 at 25°C/4°C                   Solubility:  Practically insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:  Disaster hazard-dangerous-toxic fumes-NOX and chlorides
                                             AIV-14

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                                                                                   PCNB
                               PRODUCTION DATA
Annual U.S.
 Production:   3 x 106 Ibs.

Fraction of
 Dispersion:    Estimated as 1.0

Release Rate (million Ibs/yr): 3.0
                      Consumption:

                      Fraction of Pro-
                       duction Lost 0.01
Acute Toxicity
      LDSO
                                 TOXICITY DATA
  Dosage
1650 mg/kg
1650 mg/kg
 Animal
rat
mammal
  Route
oral
unreported
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
   Neoplastic effects:
      TD,
        Lo
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                          135 gm/kg (77 weeks)    mouse
 576 mg/kg (12 weeks)   mouse
                      TLV:
                                         oral
                   skin
                                       AIV-15

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PCP

                                     CHEMICAL  NAME

    CAS Number:   87-86-5
    Chemical Name:    Pentachlorophenol
    Synonyms:  PCP (and salts)
    Molecular
     Formula:  C6HC15O
    Chemical Properties
       Molecular Weight:  266.32                       Physical State:  Solid
       Vapor Pressure:    40 mm at 211.2°C              Vapor Density:
       Boiling Point:    310°C (decomposes) at 759 mm     Melting Point:   174°C
       Density:  1.978 at 22°C/4°C                      Solubility:   Slightly soluble
       Octanol/Water Parti-
        tion Coefficient:  5.01
    Environmental Persistence
       BOD:
       Atmospheric Reactivity:
    Safety Hazard:   Disaster hazard-dangerous-toxic fumes-chlorides
                                             AIV-16

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                                                                                       PCP
                                PRODUCTION DATA

Annual U.S.
 Production:   46.0 x 106 Ibs. (1969 capacity)        Consumption:  50.0 x 106 Ibs. (197S)
Fraction of
  Dispersion:

Release Rate (million Ibs/yr):
                     Fraction of Pro-
                      duction Lost:  0.015
                                  TOXICITY DATA
Acute Toxicity
      LDSO
      TDLO
 27 mg/kg
105 mg/kg
 56 mg/kg
100 mg/kg
 29 mg/kg
Animal
rat
rat
rat
rat
human
  Route
oral
skin
intraperitoneal
subcutaneous
oral
 Non-lethal Acute Effects:
      Irritation of skin, eyes, and mucous membranes
      Nausea and vomiting
Chronic Toxicity

   U.S. Occupational Standard:   (air) TWA 500 /jg/m3
   Carcinogenicity:
       May be associated with cancer

   Mutagenicity:
       Mutagen in laboratory
   Teratogenicity:

   Other Chronic Effects:
                     TLV:  500Mg/m3
                                         AIV-17

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Pentaerythritol
                                     CHEMICAL  NAME


    CAS Number:   115-77-5

    Chemical Name:    2,2-bis(Hydroxymethyl)-l,3-propanediol

    Synonyms:     Pentek                     PE 200
Pentek
Penetek
Tetramethylol
    Molecular
     Formula:
Pentaerythrite
Monopentaerythritol
Tetrahydroxymethylmethane
                           CH2OH

    Structure:   HO - CH, - C - CH,OH
                       2   !      2

                           CH2OH
    Chemical Properties

       Molecular Weight:  136.1

       Vapor Pressure:

       Boiling Point:   276°C at 30 mm (sublimes)

       Density:     1.399 at 25°C/4°C

       Octanol/Water Parti-
        tion Coefficient:
                                  Physical State:    Solid

                                  Vapor Density:

                                  Melting Point:    262°C

                                  Solubility:  Soluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
            Fire-moderate
                                            AIV-18

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                                                                   Pentaerythritol
                              PRODUCTION DATA

Annual U.S.
 Production:   100.4 x 106lbs. (1975)              Consumption:    89 x 106 Ibs. (1975)

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:    0.015

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-19

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Pentane
    CAS Number:   109-66-0

    Chemical Name:   Pentane

    Synonyms:  Amylhydride
    Molecular
     Formula:  C5Hi2
    Structure:   CH3CH2CH2CH2CH3
                                     CHEMICAL  NAME
    Chemical Properties

       Molecular Weight:   72.15

       Vapor Pressure:     400 mm at 18.5°C

       Boiling Point:   36.1°C

       Density:     0.626 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:  Liquid

Vapor Density:  2.48

Melting Point: -129.72°C

Solubility:   Slightly soluble (0.03 gm/100 ml H2O)
    Safety Hazard:  Fire-very dangerous
                  Explosion - severe
                                            AIV-20

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                                                                                 Pentane
                               PRODUCTION DATA

Annual U.S.
 Production:  478 x 106 Ibs. (1964) (all pentanes)     Consumption:
Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                                               Fraction of Pro-
                                                duction Lost: 0.015
Acute Toxicity
                                 TOXICITY DATA

                           Dosage               Animal
                                                                     Route
Non-lethal Acute Effects:
      Narcotic in high concentrations
      CNS effects
      TCLO               1 30,000 ppm
      Irritation of eyes and respiratory tract
                                               human
                                                                  inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 1000 ppm
   Carcinogenicity:   Carcinogen


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                               TLV:  1000 ppm
                                        AIV-21

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Pentylene


                                     CHEMICAL  NAME


    CAS Number:   513-3S-9

    Chemical Name:    2-Methyl-2-butene

    Synonyms:     Amylenes (mixed)
                  Trimethylethylene
                  3-Methyl-2-butene
    Molecular
     Formula:     CSH10
                      CH3
    Structure:    CH3 - C = CH - CH3
    Chemical Properties

       Molecular Weight:  70.14                        Physical State:    Liquid

       Vapor Pressure:                                Vapor Density:

       Boiling Point:   38.57°C at 760 mm               Melting Point:    -133.77°C

       Density:    0.6623 at 20°C/4°C                  Solubility:   Insoluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
            Fire-dangerous
                                             AIV-22

-------
                                                                            Pentylene

                              PRODUCTION DATA
Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
         Moderate effects from ingestion or inhalation
                                       AIV-23

-------
Perchloroethylene
                                      CHEMICAL  NAME
    CAS Number:  127-18-4

    Chemical Name:    Tettachloroethylene

    Synonyms:   Perchloroethylene
                Ethylene tetrachloiide

    Molecular
      Formula:   C2C14
Carbondichloride
Tetrachloioethene
    Structure:
    Chemical Properties

       Molecular Weight:  165.82

       Vapor Pressure:    18.47 mm at 25°C

       Boiling Point:    121.20°C at 760mm

       Density:  1.6227 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
          Activity: RO2ti^ = 220 years
                  031^4 = 11 years
                  OH: t% = 8 days
          Photochemical Degradation:  Not photoreactive

    Safety Hazard:  Disaster hazard-dangerous-toxic fumes-chlorides
         Physical State:  Liquid

         Vapor Density:  5.83

         Melting Point:  -19°C

         Solubility:   Insoluble (H2O)
                                              AIV-24

-------
                                                                    Perchloroethylene
                                PRODUCTION DATA
Annual U.S.
 Production:   673.7 x 106 Ibs. (1975)

Fraction of
 Dispersion:   0.89

Release Rate (million Ibs/yr):  688.0
                       Consumption:  515 to 575 x 106 Ibs. (1975 estimate)
                       Fraction of Pro-
                        duction Lost:  0.015
Acute Toxicity
         TOXICITY DATA

   Dosage               Animal
2200 mg/kg            rabbit
5000 mg/kg            rabbit
4000 mg/kg            cat
  85 mg/kg            dog
4000 mg/kg            dog
4000 ppm (4 hours)     rat
  Route
subcutaneous
oral
oral
intravenous
oral
inhalation
Non-lethal Acute Effects:
      TCLO                 600 ppm (10 min)      man-inhalation—central nervous systems effects
                           280 ppm (2 hours)      man-inhalation—eye irritant
                           230 ppm              human-inhalation-systemic effects
      Local irritant; lachrymation; irritation of nose and throat; vomiting, nausea; drowsiness;
      attitude of irresponsibility; anesthetic; headache; dermatitis; irritation of gastrointestinal tract
      following ingestion.
Chronic Toxicity

   U.S. Occupational Standard:   (air)  TWA 100 ppm
                                  continuous 200 ppm
                                  peak 300 ppm for 5 minutes in 3 hours

   Carcinogenicity:
      Not carcinogenic according to Dow Chemical Co.
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                       fLV:
                                         AIV-25

-------
Perchloromethyl mercaptan
                                    CHEMICAL NAME
CAS Number:   75-70-7

Chemical Name:   Trichloromethanetniol

Synonyms:     Perchloromethyl mercaptan
Molecular
  Formula:
                  CHCljS
Structure:
                             Cl
                             1
                        Cl — C — SH
                             1_
                             Cl
Chemical Properties

   Molecular Weight:  151.43

   Vapor Pressure:

   Boiling Point:

   Density:

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
                                                  Trichloromethyl mercaptan
                                              Physical State:

                                              Vapor Density:

                                              Melting Point:

                                              Solubility:
                                                                   Liquid
    Safety Hazard:
             Disaster hazard-dangerous-toxic fumes-chlorides
                                            AIV-26

-------
                                                   Perchloromethyl mercaptan
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                              PRODUCTION DATA
                      Consumption:

                      Fraction of Pro-
                       duction Lost:
                                TOXICITY DATA
Acute Toxicity
        LDSO
   Dosage
 83 mg/kg
483 ppm (10 minutes)
 58 ppm (10 minutes)
 58 ppm (15 minutes)
Non-lethal Acute Effects:
        Eye
        TCLo            45 ppm
        Irritation of respiratory tract
                      Animal
                     rat
                     human
                     mouse
                     cat
                      human
Chronic Toxicity

   U.S. Occupational Standard: (air) TWA  800 mg/m3



   Carcinogenicity:
   Mutagenicity:
        TCLO
   Teratogenicity:

   Other Chronic Effects:
15 mg/m (68 weeks)    rat
                     TLV:
  Route
oral
inhalation
inhalation
inhalation
                                        inhalation
                                        inhalation
                                      AIV-27

-------
o-Phenetidine
                                     CHEMICAL NAME
    CAS Number:   94-70-2

    Chemical Name:    o-Phenetidme

    Synonyms:  2-Aminophenetole
               2-Ethoxyaniline

    Molecular
      Formula:  C8H,,NO
    Structure:
    Chemical Properties

       Molecular Weight:   137.2

       Vapor Pressure: 1 mm at 67°C

       Boiling Point:   232.5°C at 760 mm

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State: Liquid

Vapor Density:

Melting Point:  -20° C

Solubility:   Slightly (H2O)
    Safety Hazard:  Disaster hazard-dangerous-toxic fumes-NOx
                                            AIV-28

-------
                                                                       o-Phenetidine
                              PRODUCTION DATA

Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity              Dosage              Animal               Route


Sublethal acute effects:
     Highly toxic
     Palpitation
     Dyspnea
     Cyanosis
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:    Recognized carcinogen


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-29

-------
p-Phenetidine
                                     CHEMICAL  NAME
    CAS Number:    156-434

    Chemical Name:    p-Phenetidine

    Synonyms:  4-Ethoxybenzenamine
               4-Aminophenetole
               4-Ethoxyaniline
    Molecular
      Formula:  C8HnNO
    Structure:
                   ^

                     OCH2CH3


    Chemical Properties

       Molecular Weight:   137-2

       Vapor Pressure: <10mmat 25°C

       Boiling Point:   253 to 255°C

       Density:  1-0652 at 16°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:  L»quid

Vapor Density:  4-73

Melting Point:   2to4°C

Solubility:   Slightly soluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:  Disaster hazard-dangerous-toxic fumes-NOX
                                             AIV-30

-------
                                                                     p-Phenetidine
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:   Recognized carcinogen


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-31

-------
Phenol
                                      CHEMICAL NAME
    CAS Number:   108-95-2

    Chemical Name:    Phenol

    Synonyms:   Carbolic acid
                Phenic acid
                Phenylic acid
    Molecular
      Formula:   C6H6O
Oxybenzene
Phenyl hydroxide
Hydroxy benzene
    Structure:
    Chemical Properties

       Molecular Weight:   94.11

       Vapor Pressure:  0.530 mm at 25°C
                      1 mm at 40°C
       Boiling Point:   181.9°C at 760mm

       Density:   1.05 76 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:     96% of theoretical after 20 days at 20° C
                 Total theoretical oxygen demand = 2.4 gm/gm
       Atmospheric Reactivity:
           Activity: reacts with oxidizing materials
                   RO2tvi = 5 mos. j
                   O3  tvi = 9.6 hours
                   OHtfc=nday~

           Is rapidly biodegiaded to catechol, CHj, CHa and -keto-adipate

    Safety Hazard:  Fire-moderate
                   Disaster hazard-dangerous-toxic fumes
              Physical State:  Solid

              Vapor Density:  3.24

              Melting Point:   42.5to43°C

              Solubility:   Soluble (86.6 gm/1 H2O)
                          Infinitely soluble in hot H
                                              AIV-32

-------
                            Phenol
PRODUCTION DATA
Annual US
Production: 2,399 x 106 Ibs. (1974)
Fraction of
Dispersion:
Release Rate (million Ibs/yr): 47.0
TOXICITY
Acute Toxicity Dosage
LDSO • 414 mg/kg
669 mg/kg
250 mg/kg
344 mg/kg
300 mg/kg
LDLo 140 mg/kg
650 mg/kg
80 mg/kg
50 mg/kg
420 mg/kg
2000 mg/kg
620 mg/kg
620 mg/kg
180 mg/kg
300 mg/kg
450 mg/kg
290 mg/kg
Non-lethal Acute Effects:
Gastrointestinal 14 mg/kg ,
Liver and kidney damage
Convulsions
Estrous cycle disturbances
Decreased brain cortex activity
Chronic Toxicity
U.S. Occupational Standard:
Carcinogenicity: TD^ 4000 mg/kg (20 weeks)
Mutagenicity:
Teratogenicity:
Other Chronic Effects: Nausea and vomiting
Paralysis

Consumption:
Fraction of Pro-
duction Lost:

DATA
Animal
rat
rat
rat
mouse
mouse
human
rat
cat
cat
rabbit
rabbit
rabbit
rabbit
rabbit
guinea pig
guinea pig
frog

human






mouse

TLV: Sppm



2,300 x 106 Ibs. (1974 estimate)

0.015


Route
oral .
skin
intraperitoneal
subcutaneous
oral
oral
subcutaneous
subcutaneous
intravenous
oral
skin
intraperitoneal
subcutaneous
intravenous
intraperitoneal
subcutaneous
parenteral

oral






skin




AIV-33

-------
Phenothiazine
                                     CHEMICAL  NAME
    CAS Number:   92-84-2

    Chemical Name:    Phenothiazine

    Synonyms:  Thiodiphenylamine
               Dibenzo-l,4-thiazine

    Molecular
      Formula:  C12H9NS(tiicyclic)
                        H
                        I
                        .N
                 (f  ~V
    Structure:
    Chemical Properties

       Molecular Weight:  199.3

       Vapor Pressure:

       Boiling Point:   371°C at 760 mm

       Density:

       Octanol/Water Parti-
         tion Coefficient:  4.15

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:  Solid

Vapor Density:
Melting Point:   185.5 to 185.9 C
Solubility:  Slightly (H2O)
                                            AIV-34

-------
                                                                       Phenothiazine
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION  DATA
                   Consumption:

                   Fraction of Pro-
                     duction Lost:
Acute Toxicity
      LDso
      TOXICITY DATA

Dosage               Animal
5 gm/kg              rat
Non-lethal Acute Effects:
      Hemolytic anemia
      Toxic degeneration of liver
      Skin irritation and photosensitization
      TDLo              425 mg/kg (5 days)
                    child
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 5 mg/m3



   Carcinogsnicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                   TLV: Smg/nV*
  Route
oral
                                      oral
                                       AIV-35

-------
o-Phenylenediamine
                                    CHEMICAL NAME
    CAS Number:  95-54-5

    Chemical Name:    o-Phenylenediamine

    Synonyms:   o-Diaminobenzene
               1,2-Diamobenzene

    Molecular
     Formula:   C6H8N2
    Structure:
                       NH,,
                       NH.,
    Chemical Properties

       Molecular Weight:  108.1

       Vapor Pressure:    Negligible

       Boiling Point:   257°C at 760 mm

       Density:

       Octanol/Water Parti-
        tion Coefficient:  0.37

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:   Fire-slight
Physical State: Solid

Vapor Density:

Melting Point:  102 to 103°C

Solubility:   Soluble (hot H2O)
                                           AIV-36

-------
                                                            o-Phenylenediamine
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICiTY DATA

Acute Toxicity              Dosage              Animal              Route
     LDLo               600 mg/kg            rat                subcutaneous
                         600 mg/kg            mouse             subcutaneous

Non-lethal Acute Effects:
     Skin and eye irritant
     Liver damage
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV: 100/ag/m3 (skin)

   Other Chronic Effects:
                                       AIV-37

-------
p-Phenylenediamine
                                    CHEMICAL NAME
    CAS Number:   106-50-3

    Chemical Name:   p-Phenylenediamine

    Synonyms:  1 ,4-Diaminobenzene
               Ursol D

    Molecular
     Formula:  C6H8N2
                 NH2
    Structure:
               V;

                 NH
                    2
    Chemical Properties

       Molecular Weight:   108.16                      Physical State:  Solid

       Vapor Pressure:  lmmat98.8°C                 Vapor Density: 3.72

       Boiling Point:   267°C                         Melting Point:  140°C

       Density:  1.0696 at 58° C/4°C                    Solubility:   Slightly soluble (H2O)
             ,„.,    n  .                                        Soluble (hot H0O)
       Octanol/Water Parti-                                                   1
        tion Coefficient:   -0.26

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:  Disaster hazard-dangerous toxic fumes
                                            AIV-38

-------
                                                               p-Phenylenediamine
Annual U.S.
 Production:   48 x 106 Ibs.

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION DATA
                      Consumption:
                      Fraction of Pro-
                       duction Lost: 0.01S
Acute Toxicity
        TOXICITY DATA

                      Animal
100 mg/kg             rat
 50 mg/kg      .       rat
170 mg/kg             rat
100 mg/kg             dog
 17 mg/kg             dog
100 mg/kg             cat
100 mg/kg             rabbit
200 mg/kg             rabbit
 17 mg/kg             mammal
  Route
oral
intraperitoneal
subcutaneous
subcutaneous
intravenous
oral
oral
subcutaneous
intravenous
Non-lethal Acute Effects:
      Severe skin and eye irritant
      Liver damage
      Asthma
Chronic Toxicity

   U.S. Occupational Standard:   (air) TWA 100 Mg/m3 (skin)



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                      TLV:
                                       AIV-39

-------
Phenylhydrazine
                                     CHEMICAL  NAME
    CAS Number:   100-63-0

    Chemical Name:    Phenylhydrazine

    Synonyms:  Hydiazinobenzene
    Molecular
     Formula:  C6H8N2


                        H
                        I
                        N-NH2
                f   ir
    Structure:
    Chemical Properties

       Molecular Weight:   108.14

       Vapor Pressure:  1 mm at 71.8°C

       Boiling Point:   243.5°C at 760 mm

       Density:   1.0978 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:  1.25

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:  Solid

Vapor Density:  3.7

Melting Point:  19.35°C

Solubility:   Very slightly soluble (H2O)
            Soluble in hot fO
                                            AIV-40

-------
                                                                     Phenylhydrazine
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION  DATA
                      Consumption:

                      Fraction of Pro-
                       duction Lost:
                                  TOXICITY DATA
Acute Toxicity
      LDSO


      LDLo
  Dosage
188 mg/kg
 80 mg/kg
 80 mg/kg
 40 mg/kg
175 mg/kg
170 mg/kg
200 mg/kg
120 mg/kg
 80 mg/kg
300 mg/kg
 Animal
rat
rabbit
guinea pig
rat
mouse
mouse
dog
dog
rabbit
frog
  Route
oral
oral
oral
subcutaneous
oral
subcutaneous
oral
intravenous
subcutaneous
unknown
 Non-lethal Acute Effects:        •
      Hemolysis of red blood cells
      Gastrointestinal disturbances
      Dermatitis
      Nausea and vomiting


Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 5 ppm (skin)
   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:  5 ppm

   Other Chronic Effects:    Damage to kidney and liver
                         Dermatitis
                                         AIV-41

-------
Phosgene
    CAS Number:   75-44-5

    Chemical Name:    Phosgene

    Synonyms:  Caibonoxychloiide
               Carbonylchloride
               CG
    Molecular
     Formula:  CC12O
                                     CHEMICAL NAME
    Structure:
                      O
                  Cl
                          Cl
    Chemical Properties

       Molecular Weight:  98.92

       Vapor Pressure:  1428 mm at 25°C

       Boiling Point:  7.56°C at 760 mm

       Density:  1.392 at 19°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
Physical State:  Gas or volatile liquid

Vapor Density:  3.4

Melting Point:  -118°C

Solubility:  Decomposes in H2O
    Safety Hazard:   Disaster hazard—highly dangerous-toxic fumes
                                             AIV-42

-------
                                                                               Phosgene
                               PRODUCTION DATA
Annual U.S.
 Production:  728.2 x 106lbs. (1973)

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                      Consumption:  1,066 x 10b ibs. (1973)

                      Fraction of Pro-
                       duction Lost:  0.015
Acute f oxicity
      LCSO
      Irritant

Non-lethal Acute Effects:
      Corneal opacity
      Nausea
        TOXICITY DATA

                       Animal
  75 ppm (30 months)   rat
 110 ppm (30 months)   mouse
1087 ppm (1 month)     monkey
1482 ppm (1 month)     cat
3211 ppm (1 month)     rabbit
 141 ppm (30 months)   guinea pig
  79 ppm (30 months)   dog
  31 mg/m  (20 months) guinea pig
  25 ppm (30 months)   human
  Route
inhalation
inhalation
inhalation
inhalation
inhalation
inhalation
inhalation
inhalation
inhalation
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:   Pulmonary edema
                      TLV:  0.1 ppm
                                         AIV-43

-------
Phthalic anhydride
                                     CHEMICAL  NAME
    CAS Number:   85-44-9

    Chemical Name:    Phthalic anhydride

    Synonyms:   Phalandione
    Molecular
      Formula:   C8H4O3
                          -o

    Structure:     \   /
                            O
    Chemical Properties

       Molecular Weight:  148.12                      Physical State:   Solid

       Vapor Pressure:  1 mm at 96.5°C                  Vapor Density:  5.10

       Boiling Point:    295.1°C                        Melting Point:   131.61°C

       Density:  1.527 at 4°C                          Solubility:   Soluble slightly (hot H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   (Common air contaminant)
                              Reacts with oxidizing materials
    Safety Hazard:   Explosion-moderate
                                             AIV-44

-------
                                                               Phthalic anhydride
                              PRODUCTION DATA
Annual U.S.
 Production:
              933 x 10" Ibs.
              (703.7 x 10° Ibs. in 1975)

              0

Release Rate (million Ibs/yr): 14.0
Fraction of
 Dispersion:
Consumption:   933.7 x 106 Ibs.

Fraction of Pro-
 duction Lost:  0.015
                                 TOXICITYDATA
Acute Toxicity
      LDSO
                          Dosage
                        4020 mg/kg
                         800 mg/kg
                         100 mg/kg
 Animal
rat
guinea pig
rat
  Route
oral
oral
oral
 Non-lethal Acute Effects:
      Conjunctivitis
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 2 ppm



   Carcinogsnicity:


   Mutagenicity:

   Teratogenicity:                               fLV: 2 ppm

   Other Chronic Effects:     Emphysema and asthma
                                       AIV-45

-------
Phthalimide
                                     CHEMICAL NAME
    CAS Number:   8541-6

    Chemical Name:    lH-Isoindole-l,3(2H)-dione

    Synonyms:  Phthalimide
               1,3-Isoindoledione
               Phthalic acid, imide
    Molecular   Benzoimide
     Formula:  C8HSNO2
    Structure:
    Chemical Properties

       Molecular Weight:  147.14

       Vapor Pressure: < 10 mm at 25°C

       Boiling Point:   238°C (sublimes)

       Density:

       Octanol/Water Parti-
        tion Coefficient:  1-69

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:  Disaster hazard-slight-toxic fumes
Physical State:  Solid

Vapor Density:

Melting Point:  238°C

Solubility:  Slightly soluble (H2O)
                                             AIV-46

-------
                                                                        Phthalimide
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-47

-------
Phthalonitrile
                                     CHEMICAL NAME
    CAS Number:   91-15-6

    Chemical Name:    Phthalonitrile

    Synonyms:  o-Dicyanobenzene
               1,2-Benzene dicaibonitiile

    Molecular
     Formula:  CgH4N2
    Structure:
    Chemical Properties

       Molecular Weight:  128.14

       Vapor Pressure:

       Boiling Point:   187°C (sublimes)

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:  Disaster hazard-dangerous-cyanides
Physical State:  Solid

Vapor Density: 4.42

Melting Point:  141°C

Solubility:  Slightly soluble (H2O)
                                              AIV-48

-------
                                                                       Phthalonitrile
                              PRODUCTION DATA

Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage              Animal               Route
      LD50               1860mg/kg            rat                 oral
                           62 mg/kg            rat                 intraperitoneal
                           65 mg/kg            mouse              oral
                           35 mg/kg            mouse              intraperitoneal
                           46 mg/kg            mouse              subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-49

-------
Picloram
                                     CHEMICAL  NAME
    CAS Number:   1918-02-1

    Chemical Name:    4-Amino-3,5,6-trichloropicolinic acid

    Synonyms:     Picloram
    Molecular
      Formula:
C6H3C13N202
                        NH-,
                   Cl
    Structure:
                             Cl
                   Cl   ^  C - OH
                              II
                             o


    Chemical Properties

       Molecular Weight: 214.46

       Vapor Pressure:   6.16 x 10   mm at 35°c

       Boiling Point:  215°C (decomposes)

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:

          Photo decomposition



    Safety Hazard:
                                  Physical State:    Solid

                                  Vapor Density:

                                  Melting Point: 209.5to210°C
                                               (decomposes at 215 C)
                                  Solubility:   Soluble (H2O) (430 ppm at 25°C)
                                             AIV-50

-------
                                                                              Picloram

                              PRODUCTION DATA
Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity              Dosage              Animal               Route
        LDSO            3750mg/kg            rat                 oral
                        1500 mg/kg            mouse              oral
                        2000 mg/kg            rabbit              oral
                        2000 mg/kg            mammal            unknown
        Low toxicity to humans
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 10 mg/m3



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-51

-------
B-Picoline
                                     CHEMICAL NAME
    CAS Number:    108-99-6

    Chemical Name:   3-Picoline

    Synonyms:   0-Kcoline
                3-Methylpyridine

    Molecular
     Formula:   C6H7N
    Structure:
                         CH,
    Chemical Properties

       Molecular Weight:  93.12

       Vapor Pressure:  10.46 mm at 25°C

       Boiling Point:    144.1°C at 760 mm

       Density:   0.9566 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
Physical State:     Liquid

Vapor Density:     3.71

Melting Point:   -18.3°C

Solubility:   Infinite (H2O)
    Safety Hazard:
          Fire-moderate
          Disaster hazard-dangerous-toxic fumes-NOx
                                              AIV-52

-------
                                                                          B-Picoline

                              PRODUCTION DATA
Annual U.S.
 Production:    >60 x 106 Ibs. (1976)              Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:    0.015

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage               Animal               Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-53

-------
a, B-Pinene
                                      CHEMICAL  NAME
    CAS Number:   a': 80-56-8
                             ft: 5947-71-7
rilom. ,, Wa_0.   a: 2,6,6-Trimethylbicyclo (3.1.1)ihept-2-ene
Chemical Name:   a -,",_.    ,  ,,.    ,  ,,,,,,     ,
                p : 2,6,6-Tnmethylbicyclo (3.1.1) hept-1-ene

Synonyms:    a: 2-Pinene
    Molecular
      Formula:
              C,0H
                   10"16
                                   : 3-Pinene
                                      Nopinene
                                      Pseudopinene
    Structure:
    Chemical Properties

       Molecular Weight:  136.24
                                                 Physical State:    Liquid
       Vapor Pressure:  1 mm at 37.3 C (unspecified isomer) Vapor Density:   4.7 (unspecified isomer)

                                                     Melting Point:  a:  -55°C
   „ .,.   „ .    a: 156.1  Cat 760mm
   Bo.lmgPomt:  p: 164 to 166°C at 760mm
       Density:  a '• 0.8582 at 20 C/4 C
                /3": 0.8654 at 20°C/4°C
       Octanol/Water Parti-
         tion Coefficient:
                                                 Solubility: Insoluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
             Fire-moderate
                                              AIV-54

-------
                                                                           a,  B-Pinene

                               PRODUCTION DATA
Annual U.S.
 Production:  120.7 x 106 Ibs. (1968)                Consumption:
             (isomer not specified)
Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost:  0.015

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route


Non-lethal Acute Effects:
        Irritant to skin and mucous membranes
        Nephritis
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
                                        AIV-55

-------
Piperazine
                                     CHEMICAL  NAME
    CAS Number:   110-85-0

    Chemical Name:    Piperazine

    Synonyms:   Hexahydropyrazine
                Dimethylenediamine

    Molecular
      Formula:   C4Hj0N2


                   H
    Structure:
     Chemical Properties

       Molecular Weight:  86.14

       Vapor Pressure:
       Boiling Point:    146 C at 760 mm

       Density:  1.1

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOO:

       Atmospheric Reactivity:
     Safety Hazard:   Disaster hazard-dangerous-toxic fumes-NOx
Physical State:  Solid

Vapor Density:  3.0

Melting Point:   To6°C
Solubility:   Very soluble (H2O)
                                             AIV-56

-------
                                                                            Piperazine
                               PRODUCTION DATA
Annual U.S.
  Production:   4.6 x 10° ibs. (1968)

Fraction of
  Dispersion:

Release Rate (million Ibs/yr):
                      Consumption:

                      Fraction of Pro-
                       duction Lost: 0.015
Acute Toxicity
     LDSO

Non-lethal Acute Effects:
     Irritant to skin
     Blurred vision
                                 TOXICITY DATA
   Dosage
1100mg/kg
 Animal
mouse
   Route
subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                      TLV:
                                        AIV-57

-------
Piperonyl butoxide
                                      CHEMICAL  NAME


    CAS Number:   51-03-6

    Chemical Name:    o-[2-(2-Butoxyethoxy) ethoxy] -4,5-(methylenedioxy)-2-propyltoluene

    Synonyms:   Piperonyl butoxide
                Butylcarbityl (6-propylpiperonyl) ether
                Butacide
    Molecular
      Formula:   C19H3oOs
    Structure:
                                       CH2CH3
     Chemical Properties

       Molecular Weight:   338.4

       Vapor Pressure:

       Boiling Point:    180°C at 1 mm

       Density:   1.04 to 1.07 at 20°C/20°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:   Liquid

Vapor Density:

Melting Point:

Solubility:  Insoluble (
     Environmental Persistence

       BOD:

       Atmospheric Reactivity:    Reacts with oxidizing materials
     Safety Hazard:  Fire-slight
                                              AIV-58

-------
                                                              Piperonyl  butoxide
                              PRODUCTION DATA
Annual U.S.
 Production:   1.0xl06lbs.

Fraction of
 Dispersion:   Estimated at 1.0

Release Rate (million Ibs/yr): 1.0
                     Consumption:

                     Fraction of Pro-
                      duction Lost: 0.015
                                TOXICITY DATA
Acute Toxicity
     LDso
11500mg/kg
 380'0 mg/kg
 7500 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
rat
mouse
rabbit
                     TLV:
                                         Route
oral
oral
oral
                                      AIV-59

-------
Planavin
                                     CHEMICAL NAME
    CAS Number:      4726-14-1

    Chemical Name:    4-(Methyl sulfonyl)-2,6-dinitio-N,N-dipiopylaniline

    Synonyms:   Planavin
    Molecular
     Formula:
                     6       ,N02
    Structure:   CH3 ~
                         =\    , CH,CH,CH,
                     O
                              NO
Chemical Properties

   Molecular Weight:  345.41

   Vapor Pressure:

   Boiling Point:

   Density:

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
                                                    Physical State:   Solid or liquid

                                                    Vapor Density:

                                                    Melting Point:   151 to 152°C

                                                    Solubility:
    Safety Hazard:
                                             AIV-60

-------
Annual U.S.
 Production:

Fraction of
 Dispersion:
              2.0
              Estimated as 1.0

Release Rate (million Ibs/yr): 2.0
                              PRODUCTION DATA
Consumption:
Fraction of Pro-
 duction Lost:  0.015
                                                                             Planavin
Acute Toxicity
      LDso
                        2000 mg/kg
                        2000 mg/kg
                                TOXICITY DATA
 Animal
rat
mammal
  Route
oral
unieported
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                             TLV:
                                       AIV-61

-------
Polyacrylamide
                                    CHEMICAL  NAME
    CAS Number:   9005-05-8

    Chemical Name:   2-Propenamide,homopolymer

    Synonyms:     Polyacrylamide
                  Acrylainide, polymers

    Molecular
     Formula:     (C3H5NO)n
                           O
                 __....  -       — .-_
    Structure:    (CH2 = CH - C - NH2)n
    Chemical Properties

       Molecular Weight:  (71.08)n

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:    Solid

Vapor Density:

Melting Point:

Solubility:   Soluble (H26)
                                            AIV-62

-------
                                                                   Polyacrylamide
                              PRODUCTION DATA

Annual U.S.
 Production:   12.8 x 106 ibs.                     Consumption:     12.8 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:   1.0                               duction Lost:    0.03

Release Rate (million Ibs/yr): 13.2
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogsnicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-63

-------
Polybutenes



                                     CHEMICAL NAME


    CAS Number:   9003-29-6

    Chemical Name:    Butene, homopolymers

    Synonyms:     Polybutenes
                  Butene polymers

    Molecular
      Formula:     (C4H8)n
    Structure:   Any of several thermoplastic isotactic polymers of isobutane of varying molecular
               weight; also polymers of butene-1 and butene-2.
    Chemical Properties

       Molecular Weight:  <3000                      Physical State:     Liquid

       Vapor Pressure:    Negligible at 25°C             Vapor Density:

       Boiling Point:                                  Melting Point:     -50 to -38°C

       Density:   0.83 to 0.89                         Solubility:   Insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                                              AIV-64

-------
                                                                       Polybutenes
                              PRODUCTION DATA

Annual U.S.
 Production:   335.0 x 106 lbs.(M.W. <3000)        Consumption:     335.0 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:   0.98                             duction Lost:     0.01S

Release Rate (million Ibs/yr):  333.3
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:  .
                                       AIV-65

-------
Polychlorihated  biphenyl
                                     CHEMICAL  NAME
    CAS Number:     (a) 11097-69-1  (b) 11096-82-5

    Chemical Name:   (a) Aroclor 1254   (b) Atoclor 1260

    Synonyms:    (a) PCB 1254                      Cb) PCB1260
                 Chlorinated biphenyls               Kanechloi
                 Polychlorinated biphenyls
    Molecular
     Formula:    (exact composition unknown or undetermined)
    Structure:
                                             X = Q or H
Chemical Properties  (Aroclor 1254)

   Molecular Weight:

   Vapor Pressure:  <1 mm at 25°C

   Boiling Point:  365 to 390°C

   Density:    1-495 to 1.505 at 65°C/15.5°C

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity: Activity towards OH:
                                                    Physical State:    Liquid-solid

                                                    Vapor Density:

                                                    Melting Point:

                                                    Solubility:  Slight (H2O)
                                                  = 26 days
    Safety Hazard:
            Disaster hazard-dangerous-toxic fumes
                                             AIV-66

-------
                                                        Polychlorinated biphenyl
Annual U.S.
 Production:

Fraction of
 Dispersion:
5.495 x 106 Ibs.
1.0
                               PRODUCTION DATA
                                        Consumption:

                                        Fraction of Pro-
                                          duction Lost:
                                                 0.01
Release Rate (million Ibs/yr):    30.3
Acute Toxicity


Non-lethal Acute Effects:
        Liver damage
                    TOXICITY DATA

                                 Animal
Chronic Toxicity

   U.S. Occupational Standard:  Aroclor 1254 - 0.5 mg/m3
                           Aroclor 1242 -1.0 mg/m3

   Carcinogenicity:
      "KanedubTSOO"
  Neoplasm

       Lo	
  Carcinogenicity
KanechloF400
  Neoplasm
                         17gm/kg(49weeks)
                         2Tgrn7kg732~weeks)

                       7500mg/kgTlTyears)
        Skin effects
      	PLO
      Kanechlor 300"
        Neoplasm
          TD,
            ILo
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
           28 mg/kg
           18gm/kg(52weeics)
                                  rat
                                  mouse"
                                         human
                                         rat
                                                             Route
oral
oral

oral

oral



oral
                                        AIV-67

-------
Polyethylene and co-polymers
                                    CHEMICAL NAME
    CAS Number:   9002-88-4

    Chemical Name:   Ethylene, polymers

    Synonyms:     Polyethylene
    Molecular
     Formula:      (C2H4)n
                  H    H -i
                  I      I
    Structure:  —J-C - C
                  I      I
                       H
                  H
(chain is linear)
    Chemical Properties

       Molecular Weight:  (28.05)n

       Vapor Pressure:    Negligible mm at 25°C

       Boiling Point:  85 to 110°C

       Density:     0.92 average

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                  Physical State:    Solid

                  Vapor Density:

                  Melting Point:   85 to 110°C

                  Solubility:   Insoluble (H2O)
    Safety Hazard:
                                            AIV-68

-------
                                                Polyethylene and co-polymers
                             PRODUCTION DATA

Annual U.S.
 Production:   2295.9 x 106 Ibs.                  Consumption:   	2010.8 xlO6 Ibs.
                                                  1975: High density polymers-2,289 x 106 Ibs.
Fraction of                                              Low density polymers-4,725 x 106 Ibs.
 Dispersion:   1.0                            Fraction of Pro-
Release Rate (million Ibs/yr):  2079.7                 duction Lost .   0.03
                                TOXICITY DATA

Acute Toxicity               Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      Neoplasm
        TDLo           2120 mg/kg            rat                implant
                         330 mg/kg            mouse              implant
   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                      AIV-69

-------
Polyethylene glycol
                                     CHEMICAL  NAME


    CAS Number:   25322-68-3

    Chemical Name:    Polyethylene glycols

    Synonyms:     Polyoxyethylene                    Polyglycol ether
                  Polyglycol
                  Ethylene oxide polymer
    Molecular
     Formula:     (C2H40)nH2O
    Structure:   H (OCH2CH2)nOH
    Chemical Properties

       Molecular Weight:  200 to 6000                  Physical State:     Liquid

       Vapor Pressure:    Negligible to 25°C             Vapor Density:

       Boiling Point:                                  Melting Point:     4 to 10°C

       Density:    1.110 to 1.140 at 20°C               Solubility:   Infinite (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:   5% of theoretical after 10 days at 20°C with acclimated culture
               Total theoretical oxygen demand =1.7 (gm/gm)
       Atmospheric Reactivity:
    Safety Hazard:
             Fire-moderate
                                             AI.V-70

-------
                                                               Polyethylene glycol
                              PRODUCTION DATA

Annual U.S.
 Production:    52.4 x 106 Ibs.                     Consumption:      44.4 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:    0.70                              auction Lost:     0.015

Release Rate (million Ibs/yr): 31.8
                                 TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
                           420 mg/kg (1 year)    mouse             intravaginal
   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-71

-------
Polyethylene  glycol chloride
                                     CHEMICAL  NAME
    CAS Number:      (Not listed in 9th Chemical Index)

    Chemical Name:

    Synonyms:   Poly(ethylene glycoi) chloride
    Molecular
      Formula:   (C2H9O)nHCl
    Structure:   C1(CH2 - CH2 -O)nH
    Chemical Properties

       Molecular Weight:    100 to 600                 Physical State:  Liquid

       Vapor Pressure:  (low)                          Vapor Density:    4.31

       Boiling Point:                                  Melting Point:     -90°C to 20°C (sets)

       Density:    1.18 to 1.14at20°C/20°C             Solubility:  Miscible (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:     Disaster hazard-dangerous-toxic fumes-chlorides
                                             AIV-72

-------
                                                Polyethylene glycol chloride
                             PRODUCTION DATA

Annual U.S.
 Production:                                  Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       LDSO              1070mg/kg        rat                   oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinoganicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                      AIV-73

-------
Polyethylene terephthalate
                                     CHEMICAL  NAME


    CAS Number:   25038-59-9

    Chemical Name:   Poly(oxy-l ,2-ethanediyloxycarbonyl-l ,4-phenylenecarbonyl)

    Synonyms:
    Molecular
      Formula:
    Structure:
Polyethylene terephthalate
Polyester resin	
Poly(oxyethyleneoxyterephthaloyl)

(C,oH804)n
                                         O
    O - CH, - CH-, - O - C
                                                       O
    Chemical Properties

       Molecular Weight: (192.17)n

       Vapor Pressure:

       Boiling Point:  Decomposes

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
                                  Physical State:   Solid

                                  Vapor Density:

                                  Melting Point:     265°C

                                  Solubility:  Insoluble (H2O)
                                             AIV-74

-------
                                                 Polyethylene terephthalate
                             PRODUCTION DATA
Annual U.S.
 Production:   2500 x 106 Ibs.

Fraction of
 Dispersion:   1-0

Release Rate (million Ibs/yr):   2487.5
                 Consumption:     2450 x 10  Ibs.

                 Fraction of Pro-
                  duction Lost:    0.015
Acute Toxicity
    TOXICITY DATA

                 Animal
                  Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinoganicity:
       Neoplasm
          TDLo
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
50 mg/kg
rat
                 TLV:
implant
                                      AIV-75

-------
Polypropylene
                                     CHEMICAL  NAME
    CAS Number:     9003-07-0

    Chemical Name:   1-Propene, homopolymer

    Synonyms:    Polypropylene
                 Propene, polymers
    Molecular
      Formula:
(C3H6)n
    Structure:
                           CH,
                     CH2-C

                           H
    Chemical Properties

       Molecular Weight:    >40,000 (42.09)n

       Vapor Pressure:   Negligible at 25°C

       Boiling Point:

       Density:   0.90

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
                                  Physical State:    Solid

                                  Vapor Density:

                                  Melting Point:    167°C (isotactic)

                                  Solubility: Insoluble (H2O)
                                             AIV-76

-------
                                                                     Polypropylene
                              PRODUCTION DATA

Annual U.S.
 Production:   2,162 x 10  Ibs. (1973)              Consumption:     1,924 x 106lbs. (1973)

Fraction of                                    Fraction of Pro-
 Dispersion:   1-0                                duction Lost:    0.03

Release Rate (million Ibs/yr):   1563.2
                                TOXICITY DATA

Acute Toxicity              Dosage               Animal               Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-77

-------
Polypropylene glycol
                                     CHEMICAL NAME


    CAS Number:  25322-69-4

    Chemical Name:    a-Hydro-O-hydroxypoly [oxy (methyl-l,2-ethanediyl)]

    Synonyms:   Polypropylene glycols
                Poly (propylene oxide)
                Polyglycol
    Molecular
      Formula:
    Structure:    HO(C3H6O)nH
    Chemical Properties

       Molecular Weight:  (76.11-monomer)400 to 2000   Physical State:  Liquid

       Vapor Pressure:                                Vapor Density:

       Boiling Point:    189°C (monomer)                Melting Point:  Does not crystalize

       Density:  1.002 to 1.007                        Solubility:  Infinite (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:   Fire-slight
                                             AIV-78

-------
                                                            Polypropylene glycol
                              PRODUCTION DATA

Annual U.S.
 Production:   359.2 x 106 Ibs.                    Consumption:   302.2 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:   0.07                              duction Lost:  0.015

Release Rate (million Ibs/yr):  26.6
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
     LDSO               419 mg/kg           rat                oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenlcity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-79

-------
Polystyrene
                                     CHEMICAL  NAME
    CAS Number:   9003-53-6

    Chemical Name:    Ethynlbenzene, homopolymei

    Synonyms:  Styrene, polymers
               Polystyrene, straight (thermoplastic resins)
               Phenylethylene
    Molecular
     Formula:  (CgHg)n
           Vinylbenzene
                   CHCH,
    Structure:
                                    n = 500-2000
    Chemical Properties    (monomer)

       Molecular Weight:  104.16

       Vapor Pressure: Negligible

       Boiling Point:   145.2°C at 760 mm

       Density: 0.9060 at 20°C/4°C

       Octanbl/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:  Solid

Vapor Density:

Melting Point:  -30.63

Solubility:  Insoluble (H2O)
                                             AIV-80

-------
                                                                        Polystyrene
                              PRODUCTION DATA

Annual U.S.
 Production:   3,322 x 106 Ibs. (1973)   •           Consumption:  3,005 x 10blbs. (1973)
                                                          (2,641 x 106lbs., 1975)
Fraction of                                    Fraction of Pro-
 Dispersion:    1-0                              duction Lost: 0.03

Release Rate (million Ibs/yr):  1471
                                TOXICITY DATA

Acute Toxicity              Dosage               Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcihogenicity:
      Neoplasm
        TDLo             19mg/kg            rat                 implant

   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-81

-------
Polystyrene,  thermoplastic  resins
                                    CHEMICAL NAME


    CAS Number:   (Chemical mixture)

    Chemical Name:

    Synonyms:  Polystyrene, rubber modified (thermoplastic resins)
               Styrene, polymers

    Molecular
     Formula:  (C8H8)n
    Structure: .  Mixture of polystyrene and polybutadiene
    Chemical Properties

       Molecular Weight:

       Vapor Pressure:

       Boiling Point:

       Density:    1.01 to 1.07

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:   Solid

Vapor Density:

Melting Point:

Solubility:   Insoluble (H,O)
                                            AIV-82

-------
                                        Polystyrene,  thermoplastic resins
                             PRODUCTION DATA

Annual U.S.
 Production:     1647 x 106 ibs.                 Consumption:     1678 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:     1-0                            duction Lost:    0.03

Release Rate (million Ibs/yr):   1,727.4
                               TOXICITY DATA

AcuteToxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:  j Reports of leukemia at rubber plants


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-83

-------
Polytetrafluoroethylene
                                  CHEMICAL NAME
    CAS Number:    116-14-3

    Chemical Name:    Tetrafluoroethene

    Synonyms:   Teflon
               TFE
               Perfluoroethylene
    Molecular
     Formula:   C2F4
          •:     frO--
Structure:

               F   F'n
    Chemical Properties (Monomer)

       Molecular Weight:    100.02                   Physical State:     Gas

       Vapor Pressure:                              Vapor Density:

       Boiling Point:   -76.3°C at 760 mm             Melting Point:   -142.5°C

       Density:   1.519 at 76.3°C                    Solubility:   Insoluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Resistant to oxidation, moisture, ozone and U.V. radiation
    Safety Hazard:
          Disaster hazard—dangerous-toxic fumes—fluorides
                                          AIV-84

-------
                                                       Polytetrafluoroethylene
                              PRODUCTION DATA
Annual U.S.
 Production:    13.2 x 106 Ibs.
Fraction of
 Dispersion:
              1-0
                                             Consumption:   14.6xl06lbs.

                                             Fraction of Pro-
                                              duction Lost:  0.03
Release Rate (million Ibs/yr):   15.0
Acute Toxicity
                                TOXICITY DATA

                          Dosage              Animal
Non-lethal Acute Effects:
      Dust can cause "polymer fume fever"
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogsnicity:
      Neoplasm
        TDLo            80mg/kg
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                                                 Route
                                             rat
                                             TLV:
                                                               implant
                                      AIV-85

-------
Polyvinyl alcohol
                                     CHEMICAL  NAME
    CAS Number:   9002-89-5

    Chemical Name:    Ethanol, homopolymer

    Synonyms:
Polyvinyl alcohol
PVA
Vinyl alcohol, polymers
    Molecular
      Formula:
    Structure:  -+- CH2CH OH-+-
    Chemical Properties

       Molecular Weight:   25,000 to 300,000

       Vapor Pressure:

       Boiling Point:    >200°C (decomposes)

       Density:     1.329

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
             Fire-slight
             Explosion-slight
                                  Physical State:     Solid

                                  Vapor Density:

                                  Melting Point:

                                  Solubility:  Solubility in H2O increases
                                            with increasing molecular
                                            weight.
                                             AIV-86

-------
                                                                 Polyvinyl  alcohol
                              PRODUCTION DATA

Annual U.S.
 Production:   100 to 141 x 106 ibs. (1974)          Consumption:     141.1 x 106 Ibs. (1975)
Fraction of
 Dispersion:   1.0

Release Rate (million Ibs/yr): 104.0
                   Fraction of Pro-
                    duction Lost:   0.03
Acute f oxicity
      TOXICITY DATA

Dosage               Animal
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:
        TDLo

   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
2500 mg/kg
rat
                   TLV:
                     Route
                  subcutaneous
                                       AIV-87

-------
Polyvinyl chloride
                                      CHEMICAL  NAME
    CAS Number:   9002-86-2

    Chemical Name:   Chloroethylene, polymers

    Synonyms:     Polyvinyl chloride
                   PVC

    Molecular
      Formula:      (C2H3Cl)n
                          . H   H
    Structure:            4- C — C
                          \ H   a
     Chemical Properties

       Molecular Weight:  60,000                       Physical State:     Solid

       Vapor Pressure:    Negligible at 25°C              Vapor Density:

       Boiling Point:  Decomposes                     Melting Point:

       Density:     1.406                              Solubility:   Insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOO:

       Atmospheric Reactivity:
             Photochemical degradation: Biodegradable, photodegradable
             Unreactive to RO2,03
             Hydrolysis is slow (rates unknown)


     Safety Hazard:
             Disaster hazard-dangerous-toxic fumes
                                             AIV-88

-------
                                                                   Polyvinyl  chloride
                               PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
4,562 x 10°lbs. (1973)
1.0
Consumption:

Fraction of Pro-
 duction Lost:
4,586 x 10° Ibs. (1973)

(3,615 x!06lbs. in 1975)

0.03
Release Rate (million Ibs/yr): 4385.7
Acute Toxicity


Non-lethal Acute Effects:
         Dermatitis
                   TOXICITY DATA

             Dosage               Animal
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:    Carcinogen (sarcomas, granulomas)
         Neoplasm:
           TDLo
   Mutagenicity:

   Teratogenicity:
         Positive
   Other Chronic Effects:
           100 mg/kg
rat
                                               rat

                                               TLV:
                     Route
                   implant
                                                    intraperitoneal
                                         AIV-89

-------
Princep
                                      CHEMICAL  NAME
    CAS Number:    122-34-9

    Chemical Name:  2-Chloro4,6-bis(ethylamino)-s-triazine

    Synonyms:    2-Chloro-4,6-bis(dimethy Iamino)-s-triazine
    Molecular
      Formula:    C7Hi2ClNs
                                    Cl
    Structure:
                  CH3-CH2-N    N     N-CH2-CH3

                               H          H
    Chemical Properties

       Molecular Weight:   221.75

       Vapor Pressure:  6.1 x 10"9 mm at 20°C

       Boiling Point:

       Density:   1.0956

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
            Decomposed by ultraviolet irradiation
Physical State:   Liquid

Vapor Density:

Melting Point:    225 to 227°C

Solubility:   5 ppm H2O at 20°C
    Safety Hazard:
           Disaster hazard-dangerous—chlorides
                                              AIV-90

-------
                                                                                Princep

                              PRODUCTION DATA
Annual U.S.
 Production:     5 x 10 Ibs.                      Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:  Estimated as 1.0                      duction Lost:  0.015

Release Rate (million Ibs/yr):  5.0
                                 TOXIC!TY DATA

Acute Toxicity               Dosage              Animal               Route
       LD5o              5000mg/kg            rat                 oral
       No toxicity in man reported
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                        AIV-91

-------
Propachlor
                                     CHEMICAL  NAME


    CAS Number:    1918-16-7

    Chemical Name:     2-Chloro-N-
-------
                                                                          Propachlor



                              PRODUCTION DATA

Annual U.S.
 Production:     23xl06lbs.                     Consumption:    23 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:  Estimated as 1.0                      duction Lost:    0.01

Release Rate (million Ibs/yr):   23.2
                                 TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       LDSO              1200 mg/kg            rat                 oral
                           380 mg/kg            rabbit              skin
                           800 mg/kg            mammal            unreported
Chronic Toxicity

   U.S. Occupational Standard:




   Carcinogenicity:



   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
      Skin and eye irritant
                                       AIV-93

-------
Propane
    CAS Number:   74-986

    Chemical Name:    Propane

    Synonyms:  Dimethyl methane
    Molecular
      Formula:
                                     CHEMICAL  NAME
    Structure:   CH3 - CH2 - CH3
    Chemical Properties

       Molecular Weight:    44.09

       Vapor Pressure: 7095 mm at 25°C

       Boiling Point:   -42.07°C at 760 mm

       Density:    0.5852 at -44.5°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:    Gas

Vapor Density:    1.56

Melting Point:  -189.9°C

Solubility:   H9gm/l(H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts vigorously with oxidizing materials
    Safety Hazard:
          Fire-highly dangerous
          Explosion—severe
                                             AIV-94

-------
                                                                              Propane


                               PRODUCTION DATA

Annual U.S.
 Production:   9608.3 x 106 Ibs.                   Consumption:  9608.3 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:    0                                auction Lost:    0.01

Release Rate (million Ibs/yr):  96.1



                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal              Route


Non-lethal Acute Effects:
      Paralysis by inhalation of concentrated gas
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 1000 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:    1000 ppm

   Other Chronic Effects:
                                        AIV-95

-------
Propanil
                                      CHEMICAL  NAME
    CAS Number:    709-98-8

    Chemical Name:  N-(3,4-Dichlorophenyl)propanamide

    Synonyms:    Propanil
                 3,4-Dichloiopropionanilide
    Molecular
      Formula:
             C9H9C12NO
                        Cl
                          V^
                                  o
                     /   NK
Structure:          Cl -?    V N - C -
                      \ — /   I
                              H
                                          CH2 - CH3
     Chemical Properties

       Molecular Weight:    218.09

       Vapor Pressure:

       Boiling Point:  91 to 95°C (technical)

       Density:  1.25at25°C

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                                                Physical State:    Solid (pure compound)
                                                                Liquid (technical compound)
                                                Vapor Density:

                                                Melting Point:   85 to 89°C (pure)

                                                Solubility:   0.05%inH2O
     Safety Hazard:
            Disaster hazard-dangerous-chlorides
                                              AIV-96

-------
Annual U.S.
 Production:

Fraction of
 Dispersion:
               6.0 x 10° Ibs.
               Estimated as 1.0

Release Rate (million Ibs/yr):  6.0
                               PRODUCTION DATA
Consumption:

Fraction of Pro-
 duction Lost:
0.015
                                                                               Propanil
Acute Toxicity
       LDSO
                                 TOXICITY DATA
                           Dosage
                          1500 mg/kg
                           560 mg/kg
                          1300 rag/kg
                          1217 mg/kg
                           500 mg/kg
 Animal
 rat
 rat
 rat
 dog
 rabbit
      Route
     oral
     oral
     oral
     oral
     umeported
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                              TLV:
                                        AIV-97

-------
Propargyi alcohol
                                    CHEMICAL NAME
    CAS Number:   107-19-7

    Chemical Name:   2 Propyn-1-ol

    Synonyms:  Propiolic alcohol
    Molecular
     Formula:   C3H4O
    Structure:   HC = C - CH2OH
    Chemical Properties

       Molecular Weight:     56.07

       Vapor Pressure:

       Boiling Point:    113.6°C at 760mm

       Density:     0.9715 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:    Volatile liquid

Vapor Density:

Melting Point:   -48°C

Solubility:   Soluble (H2O)
                                           ATV-98

-------
                                                                 Propargyl alcohol
                              PRODUCTION DATA

Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
      LDSO                 0.07 mg/kg          rat                oral
      LCLo              I	2000 mg/kg          mouse             inhalation

Non-lethal Acute Effects:
      CNS depressant
      Irritant to skin and mucous membranes
Chronic Toxicity

   U.S. Occupational Standard:   (air) 1 ppm (skin)



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-99

-------
Propazine
                                     CHEMICAL  NAME
    CAS Number:    139-10-2

    Chemical Name:  2-Chloro-4,6-bis(isopropylamino)-s-triazine

    Synonyms:   Propazine
    Molecular
     Formula:   C9H16C1NS
                                Cl
    Structure:
                       CH,

                        I    I
                       CH3H
    CH,
                   H-C-N    N    N-C-H
I    I
H   CH,
    Chemical Properties

       Molecular Weight:   229.74

       Vapor Pressure:   2.9 x 10"8 mm at 20°C

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
               Physical State:   Solid

               Vapor Density:

               Melting Point:   212 to 214°C

               Solubility:    Slightly soluble
                           (8.6 ppm H2O)
    Safety Hazard:
                                            AIV-100

-------
                                                                            Propazine

                               PRODUCTION DATA
Annual U.S.
 Production:    4.0 x 106 Ibs.                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:  Estimated as 1.0                      duction Lost:  0.015

Release Rate (million Ibs/yr):  4.0
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
       LDSo              485 mg/kg             rat                 oral
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
       Neoplasm
         TDLo           22 gm/kg (82 weeks)     rat                 oral
   	            750 mg/kg (15 weeks)     rat                 subcutaneous
   Mutagenicity:
   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-101

-------
Propiolactone
                                     CHEMICAL  NAME


    CAS Number:   57.57.8

    Chemical Name:    2-Oxetanone

    Synonyms:  0-Propiolactone                        3-Hydroxypropionic acid, lactone
               Hydraacrylic acid 0 lactone
               Propanolide
    Molecular
      Formula:  C3H4O2
                      -Q
    Structure:
    Chemical Properties

       Molecular Weight:  72.06                        Physical State:    Liquid

       Vapor Pressure:                                Vapor Density:

       Boiling Point:   162°C (decomposes)              Melting Point:  -33.4°C

       Density:  1.1460at'20°C/5°C                    Solubility:   Decomposes (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
          Fire-moderate
                                           AIV-102

-------
                                                                        Propiolactone
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION DATA
                      Consumption:

                      Fraction of Pro-
                       duction Lost:
Acute Toxicity
     LD50
         TOXICITY DATA

  Dosage               Animal
345 mg/kg             mouse
  Route
intravenous
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      Carcinogen
        TDLO
      Neoplastic effects:
        TDLo
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
12,865 mg/kg (62 weeks)  hamster
56,400 mg/kg (141 weeks) guinea pigs
  3500 mg/kg (70 weeks)  rat
    20 mg/kg (34 weeks)  rat
   180 mg/kg (30 weeks)  rat
  8100 mg/kg (27 weeks)  mouse
    69 mg/kg (43 weeks)  mouse

    40 mg/kg           mouse
                      tLV:
skin
skin
oral
subcutaneous
in tra trachea!
skin
subcutaneous

intravenous
                                      AIV-103

-------
Propionaldehyde
                                     CHEMICAL NAME


    CAS Number:   123-38-6

    Chemical Name:    Propionaldehyde

    Synonyms:  Propyl aldehyde                       Propanal
               Piopylic aldehyde                     Propionic aldehyde

    Molecular
     Formula:  C3H6O



                           O
                           II
    Structure:   CH3 - CH2 - C - H
    Chemical Properties

       Molecular Weight:   58.08                       Physical State:     Liquid

       Vapor Pressure:  10mmat25°C                  Vapor Density:  2.0

       Boiling Point:   48.8°C                         Melting Point:  -81°C

       Density:     0.8058 at 20°C/4°C                 Solubility:  Soluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:     0.38

    Environmental Persistence

       BOD:    95% of theoretical

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire—dangerous
                                           AIV-104

-------
                                                                   Propionaldehyde
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION  DATA
                      Consumption:

                      Fraction of Pro-
                        duction Lost:
                                 TOXICITY DATA
Acute Toxicity
     LDso
      TC
        Lo
   Dosage
 820 mg/kg
 680 mg/kg
 800 mg/kg
 800 mg/kg
3400 mg/kg
8000 ppm (4 hours)
Non-lethal Acute Effects:
      Local irritant to respiratory tract
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
rat
mouse
rat
mouse
rabbit
rat
  Route
subcutaneous
subcutaneous
oral
oral
skin
inhalation
                      TLV:
                                       AIV-105

-------
Propionic  acid
                                     CHEMICAL NAME
    CAS Number:   79-094

    Chemical Name:    Propionic acid

    Synonyms:  Methylacetic acid
               Propanoic acid

    Molecular
     Formula:  C3H6O2
    Structure:
CH3 - CH2 - C - OH
    Chemical Properties

       Molecular Weight:   74.09

       Vapor Pressure:    4.49 at 25°C
       Boiling Point:   141°C at 760 mm

       Density:     0.992

       Octanoi/Water Parti-
        tion Coefficient:    0.52

    Environmental Persistence
       BOD:    56% of theoretical

       Atmospheric Reactivity:
    Safety Hazard:    Fire -moderate
                                 Physical State:    Liquid

                                 Vapor Density:    2.56

                                 Melting Point:  -20.8°C

                                 Solubility:   Infinite (H2O)
                                           AIV-106

-------
                                                                       Propionic  acid
                               PRODUCTION DATA

Annual U.S.
 Production:   60.4 x 106 Ibs. (1973)               Consumption:  60.4 x 106 Ibs. (1973)
                                                            (65 x 106 Ibs., 1975)
Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost: 0.015

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LDSO               1510mg/kg            rat                 oral
                         1370mg/kg            mouse              oral
                          625 mg/kg            mouse              intravenous
                         1900 mg/kg            rabbit              oral
                          500 mg/kg            rabbit     .         skin

 Non-lethal Acute Effects:
      Local irritant to eyes, skin, and mucous membranes
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogen icity:


   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
                                       AIV-107

-------
Propyl  acetate
                                     CHEMICAL  NAME
    CAS Number:    109-604

    Chemical Name:    Acetic acid, propyl ester

    Synonyms:  n-Propyl acetate
               Propyl ester of acetic acid

    Molecular
      Formula:  CSH10O2
                         O
                       	y	
    Structure:       CH3 - C - O - CH2 - CH2 - CH3
    Chemical Properties                  >

       Molecular Weight:  102.13                       Physical State:     Liquid

       Vapor Pressure:    40 mm at 28.8°C,              Vapor Density:    3.52
       Boiling Point:   T6l.6°C at 760mm               Melting Point:   -95°C
       Density:    0.8898 at 20°C/4°C                 Solubility:   Slightly (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:    72% of theoretical after 20 days at 20°C
                Total theoretical oxygen demand = 2.04 gm/gm
       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-dangerous
          Explosion-moderate
                                            AIV-108

-------
                                                                     Propyl acetate
                              PRODUCTION DATA
Annual U.S.
 Production:    32.4 x 106 Ibs.

Fraction of
 Dispersion:    0.75

Release Rate (million Ibs/yr): 24.8
                     Consumption:   32.4 x 106 Ibs.

                     Fraction of Pro-
                       duction Lost:     0.015
Acute Toxicity
     LD50
     LCLo

Non-lethal Acute Effects:
     Conjunctivitis
     Irritation of skin
        TOXICITY DATA

                      Animal
6630mg/kg            rabbit
8000 ppm (4 hours)      rat
  Route
oral
inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 200 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                     TLV:  200 ppm
                                      AIV-109

-------
Propyl  alcohol
                                      CHEMICAL  NAME
    CAS Number:   71-23-8

    Chemical Name'    Propyl alcohol

    Synonyms:   Ethyl carbinol
                Propan-1-ol
                1-Propanol
    Molecular
      Formula:   C3H8O
    Structure:      CH3 - CH2 - CH2 - OH
     Chemical Properties

       Molecular Weight:     60.11                     Physical State:    Liquid

       Vapor Pressure:  19.8 mm at 25°C                 Vapor Density:    2.07

       Boiling Point:   97°Cat760mm                  Melting Point:  -126.5°C

       Density:  0.8035 at 20°C/4°C                     Solubility:   Infinite (H2O)

       Octanol/Water Parti-
         tion Coefficient:     0.74

     Environmental Persistence

       BOD:    85% of theoretical after 20 days at 20° C
                Total theoretical oxygen demand = 2.40 gm/gm
       Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
          Fire-dangerous
          . Explosion-moderate
                                            AIV-110

-------
                                                                       Propyl alcohol
                               PRODUCTION DATA
Annual U.S.
 Production:   83.1 x 106 Ibs.

Fraction of
 Dispersion:    0-75

Release Rate (million Ibs/yr):  63.6
                    Consumption:   83.1 x 106 Ibs.
                    Fraction of Pro-
                      duction Lost:
                0.015
                                 TOXICITY DATA
Acute Toxicity
     LDSO
      LCLO

Non-lethal Acute Effects:
      Conjunctivitis
      Vomiting
      Anemia
 Dosage
  1.9g/kg
1870 mg/kg
3230 mg/kg
5700 mg/kg
 140 mg/kg
3500 mg/kg
   5 mg/kg  .
4000 ppm (4 hours)
 Animal
rats
rats
mouse
woman
mouse
rabbit
mammal
rat
  Route
oral
oral
subcutaneous
oral
oral
oral
subcutaneous
inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 200 ppm


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                    TLV:   200 ppm
                                      AIV-111

-------
Propylamine
                                    CHEMICAL  NAME
    CAS Number:   107-10-8

    Chemical Name:    Propylamine

    Synonyms:  1-Aminopropane
    Molecular
      Formula:  C3H9N
    Structure:
                     CH3 - CH2 - CH2 - NH2
    Chemical Properties

       Molecular Weight:  59.11

       Vapor Pressure:  248 mm at 20°C

       Boiling Point:   47.8°C at 760 mm

       Density:     0.7173 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
          Fire-dangerous
Physical State:  Liquid

Vapor Density:

Melting Point:  -83.0°C

Solubility:   Soluble (H2O)
                                           AIV-112

-------
                                                                         Propylamine

                               PRODUCTION DATA
Annual U.S.
 Production:  0.2 x 10° ibs. (1969)                Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:  0.015

Release Rate (million Ibs/yr):
                                 TOXICITYDATA

Acute Toxicity               Dosage               Animal               Route
      LDSO              560mg/kg             rabbit              skin
      LDLo              570mg/kg             rat                 oral.
      LC50    .         2310 ppm (4 hours)       rat                 inhalation

Non-lethal Acute Effects:
      Irritant
      Skin sensitizer
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagehicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-113

-------
Propyl chloride
                                     CHEMICAL  NAME
    CAS Number:   540-54-5

    Chemical Name:    1-Chloropiopane

    Synonyms:   n-Propylchloride
    Molecular
     Formula:   C3H7C1
    Structure:      CH3 - CH2 - CH2 - Cl
    Chemical Properties

       Molecular Weight:   78.54                       Physical State:  Liquid

       Vapor Pressure: 348.8 mm at 25°C                Vapor Density:  2.71

       Boiling Point:   46.6°C at 760 mm                Melting Point:   -122.8°C

       Density:      0.8909 at 20°C/4°C                 Solubility:   Slightly (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-dangerous
          Explosion—moderate
                                            AIV-114

-------
                                                                    Propyl chloride
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Non-lethal Acute Effects:
      Irritant to mucous membranes
      Narcotic at high concentrations
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronig Effects:
                                      AIV-115

-------
Propylene
                                     CHEMICAL NAME
    CAS Number:    115-07-1

    Chemical Name:     Propene

    Synonyms:    Propylene
                 Methylethylene
    Molecular
      Formula:
    Structure:
CH3 - CH = CH2
    Chemical Properties

       Molecular Weight:   42.09

       Vapor Pressure:  8582 mm at 25°C

       Boiling Point:    -47.4°C at 760 mm

       Density:   0.5139 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
                                  Physical State:   Gas

                                  Vapor Density:   1-46

                                  Melting Point:    -185.2°C

                                  Solubility:    Slightly (0.78 gm/1 H2O)
     Environmental Persistence

       BOD:

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
           Fire—dangerous
           Explosion - moderate
                                            AIV-116

-------
                                                                           Propylene

                              PRODUCTION DATA
Annual U.S.                q
 Production:    22 to 24 x 10* Ibs. (1974)          Consumption:    22 to 24 x 1
-------
Propylene chlorohydrin
                                    CHEMICAL NAME
    CAS Number:    78-89-7

    Chemical Name:     2-Chloro-l-propanol

    Synonyms:   Propylene chlorohydrin
                2-Chloropropyl alcohol

    Molecular
     Formula:   C3H7C1O
                         H
                          I
    Structure:       CH2 - C - CH3

                   OH   Cl
    Chemical Properties

       Molecular Weight:   94.54                      Physical State:   Liquid

       Vapor Pressure:  4.9 mm at 20°C                 Vapor Density:   3.26
       Boiling Point:    133tol34°cf                  Melting Point:
       Density:   1.1128 at 20°C/20°C                  Solubility:   Soluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
          Fire-moderate
          Disaster hazard-dangerous-toxic fumes-chlorides
                                           AIV-118

-------
                                                        Propylene chlorohydrin
                              PRODUCTION DATA

Annual U.S.
 Production:                                  Consumption:

Fraction of                                   Fraction of Pro-
 Dispersion:                                    ductiori Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
      LD50              220 mg/kg             rat                oral
                        480mg/kg             rabbit              skin
                        720 mg/kg             guinea pig          oral
      LCLo              500 mg/kg             rat                inhalation
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                     AIV-119

-------
Propylene  glycol
                                     CHEMICAL NAME
    CAS Number:   57-55-6

    Chemical Name:     l ,2-Propanediol

    Synonyms:   Propyleneglycol
                1,2-Dihydroxy propane

    Molecular
      Formula:   C3H8O2
                               OH
                               I
    Structure:       HO - CH, - C •- CH,
                               1
                               H
     Chemical Properties

       Molecular Weight:   76.11                       Physical State:   Liquid

       Vapor Pressure:  1 mm at 45.5°C                 Vapor Density:  2.62

       Boiling Point:    187.3°C                       Melting Point:

       Density:   1.0361 at 20°C/4°C                   Solubility:   Infinite (H2O)

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:     79% of theoretical after 20 days at 20°C
                 Total theoretical oxygen demand = 1.68 gm/gm
       Atmospheric Reactivity:    Reacts with oxidizing materials
     Safety Hazard:
           Fire-moderate
                                            AIV-120

-------
                                                                     Propylene glycol
                               PRODUCTION DATA
Annual U.S.
 Production:    562.6 x 106 Ibs.

Fraction of
 Dispersion:     0.32

Release Rate (million Ibs/yr):  154.0
                      Consumption:   454.8 x 106 Ibs.

                      Fraction of Pro-
                       duction Lost:  0.015
                                  TOXICITY DATA
Acute Toxicity
      LD50
  Dosage
945 mg/kg
283 mg/kg
195 mg/kg
890 mg/kg
471 mg/kg
285 mg/kg
322 mg/kg
220 mg/kg
821 mg/kg
322 mg/kg
 Non-lethal Acute Effects:
      Local irritant
      Allergen
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
Animal
rat
rat
rat
mouse
mouse
mouse
mouse
rabbit
hamster
hamster
  Route
oral
intraperitoneal
intravenous
oral
intraperitoneal
subcutaneous
intravenous
intravenous
oral
intraperitoneal
                      TLV:
                                       AIV-121

-------
Propyleneimine
                                     CHEMICAL NAME
     CAS Number:   75-55-8

     Chemical Name:    2-Methylaziridine

     Synonyms:   Propyleneimine
                1,2-Propyleneimine

     Molecular
      Formula:   CaH7N


                            H
                            J
                            N
                        	/_\	
     Structure:           H,C - C - CH,
                          *•    I      J
     Chemical Properties

        Molecular Weight:   58.10                       Physical State:   Liquid

        Vapor Pressure:                                Vapor Density:  2.0

        Boiling Point:   66 to 67°C                     Melting Point:

        Density:  0.81 at 25°C/25°C                    Solubility:   Soluble (H2O)

        Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

        BOD:

        Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
           Fire-moderate
           Disaster hazard-dangerous-toxic fumes-NOx
                                             AIV-122

-------
                                                                     Propyleneimine
                              PRODUCTION DATA

Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage              Animal               Route
     LD50               19 mg/kg            rat                oral
                         43 mg/kg            guinea pig           skin
     LCLo              500 ppm (4 hours)      rat                inhalation
                        500 ppm (1 hour)       guinea pig           inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (aii) TWA 2 ppm (skinj



   Carcinogenicity:   Carcinogen


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-123

-------
Propylene  oxide
                                     CHEMICAL  NAME
    CAS Number:   75-56-9

    Chemical Name:    Propene oxide

    Synonyms:  Propylene oxide
               Methyl oxiiane   1

    Molecular
      Formula:  C3H6O
                      O
1,2-Epoxy propane
    Structure:      CH2 - CH- CH3
    Chemical Properties

       Molecular Weight:  58.08

       Vapor Pressure: 596 mm at 25°C

       Boiling Point:   33.9°C at 760 mm

       Density:  0.8394 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:    12% of theoretical after 10 days at 20°C
                Total theoretical oxygen demand = 2.2 gm/gm
       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-highly dangerous
          Explosion-highly dangerous
   Physical State:  Liquid

   Vapor Density:  2.0

   Melting Point:   -104.4°C

   Solubility:   Soluble (650 gm/1 H2O)
                                            AIV-124

-------
                                                                    Propylene  oxide
                               PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
1640xl06lbs.
0.01
Consumption:   1620 x 106 Ibs.

Fraction of Pro-
 duction Lost:  0.015
Release Rate (million Ibs/yr):  40.8
                                 TOXICITY DATA
Acute Toxicity
      LD50
      LC50
      LCLo
            930 mg/kg
           1500 mg/kg
            690 mg/kg
           1740 ppm (4 hours)
           4000 ppm (4 hours)
           2005 ppm (4 houis)
 Animal
rat
rabbit
guinea pig
mouse
rat
dog
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 100 ppm



   Carcinogenicity:  Experimentation carcinogen


   Mutagenicity:

   Teratogenicity:
                                TLV:
   Other Chronic Effects:
      Moderately severe effects from inhalation and ingestion
  Route
 oral
 skin
 oral
.inhalation
 inhalation
 inhalation
                                        AIV-125

-------
Pyridine
     CAS Number:    110-86-1

     Chemical Name:     Pyridine

     Synonyms:   Azine
                 Azabenzene

     Molecular
      Formula:   C5HSN
                                      CHEMICAL NAME
     Structure:
     Chemical Properties

        Molecular Weight:    79.10

        Vapor Pressure: 20.3 mm at 25°C

        Boiling Point:   115.3°C

        Density:   0.982 at 20°C

        Octanol/Water Parti-
         tion Coefficient:
Physical State:   Liquid

Vapor Density:  2.73

Melting Point:   -42.0°C

Solubility:   Infinite (H2O)
     Environmental Persistence

        BOD:

        Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
           Fire-dangerous
           Explosion-severe
           Disaster hazard-dangerous-toxic fumes-cyanides
                                              AIV-126

-------
                                                                                  Pyridine
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
>60 x 10' Ibs. (1976 capacity)
Consumption:

Fraction of Pro-
 duction Lost:  0.015
Release Rate (million Ibs/yr):
                                  TOXICITY DATA
Acute Toxicity
       LD50
       LCSO
       LDLo
            Dosage
            891 mg/kg
           1000 mg/kg
           1121 mg/kg
           4000 ppm (4 hours)
           1200 mg/kg
            870 mg/kg
           4000 mg/kg
 Animal
 iat
 rat
 rabbit
 rat
 mouse
 guinea pig
 guinea pig
 Route
oral
subcutaneous
skin
inhalation
intraperitoneal
intraperitoneal
oral
 Non-lethal Acute Effects:
       Local irritant
       CNS depressant
       Kidney and liver damage
       Gastrointestinal upset
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA  5 ppm



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                TLV:   5 ppm
                                        AIV-127

-------
Randox
                                     CHEMICAL  NAME
    CAS Number:    93-71-0

    Chemical Name:     N,N-Diallyl-2-chloroacetamide

    Synonyms:    2-Chloro-N,N-diallyl acetamide
    Molecular
      Formula:    C8H12C1NO
                            O      F5
                                      2 - CH = CH2
    Structure:      Cl - CH2 - C - N
                                   CH2 - CH = CH2
    Chemical Properties

       Molecular Weight:   173.7

       Vapor Pressure:  <20 mm at 25°C

       Boiling Point:    74°C at 0.3 mm

       Density:

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:      Liquid

Vapor Density:

Melting Point:

Solubility:    Slightly (H2O)
    Safety Hazard:
           Disaster hazard-dangerous-chlorides
                                            AIV-128

-------
                                                                               Randox

                              PRODUCTION DATA
Annual U.S.           6
 Production:     10 x 10  lbs-                     Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:     Estimated as 1.0                    duction Lost:

Release Rate (million Ibs/yr):  10.0
                                TOXICITYDATA

Acute Toxicity              Dosage              Animal              Route
      LDSO        .      700mg/kg             rat                 oral
                         360 mg/kg             rat                 skin
                         700 mg/kg             mammal            umeported
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              , TLV:
   Other Chronic Effects:   Irritant to skin and eyes
                                      AIV-129

-------
Resorcinol
                                      CHEMICAL  NAME
    CAS Number:    108-46-3

    Chemical Name:   Resorcinol

    Synonyms:    1,3-Benzendiol
                 Resorcin
                 Dihydroxybenzene
    Molecular
      Formula:    C6H6O2
    Structure:
                          OH
    Chemical Properties

       Molecular Weight:    110.12

       Vapor Pressure:   1 mm at 108.4°C

       Boiling Point:  276.5°C at 760 mm

       Density:   1.285 at 15°C

       Octanol/Water Parti-
         tion Coefficient:    0.80
Physical State:    Solid

Vapor Density:    3.79

Melting Point:    110.7°C

Solubility:    Soluble (H2O)
    Environmental Persistence

       BOD:     61 % of theoretical

       Atmospheric Reactivity:     Reacts with oxidizing materials
    Safety Hazard:
            Fire-slight
                                            AIV-130

-------
                                                                             Resorcinol

                               PRODUCTION DATA
Annual U.S.
 Production:  35 x 106 Ibs. (1976 capacity)          Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost:  0.015

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity            .   Dosage               Animal               Route
        LDSO               301 mg/kg              rat                 oral
                           340 mg/kg              mouse              subcutaneous
        LDLo               270 mg/kg              frog                parenteral

Non-lethal Acute Effects:
        Dermatitis
        Eye irritant
        Methemoglobinemia
        Convulsions
        Tachycardia
        Jaundice
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
                                       AIV-131

-------
Ronnel
                                      CHEMICAL  NAME
    CAS Number:     299-84-3

    Chemical Name:   Phosphorothioic acid, O,0-dimethyl-O-(2,4,5-trichlorophenyl)ester

    Synonyms:     Ronnel
                  Fenchlorphos
                  O,O-Dimethyl-O-(2,4,5-tiichlotophenyl) phosphorothioate
    Molecular
      Formula:
    Structure:
    Chemical Properties

       Molecular Weight:     321.6
       Vapor Pressure: 8 x 10 3 mm at 25°C

       Boiling Point:

       Density:

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:    Solid

Vapor Density:

Melting Point:   41°C

Solubility:
     Safety Hazard:
                                              AIV-132

-------
                                                                                   Ronnel
Annual U.S.
 Production:   2.0 x 106 Ibs.

Fraction of
 Dispersion:    Estimated as 1.0

Release Rate (million Ibs/yr):   2.0
                                PRODUCTION DATA
                    Consumption:

                    Fraction of Pro-
                     duction Lost:
               0.015
Acute Toxicity
        LDSO
                                  TOXICITY DATA
Dosage
1760 mg/kg
1000 mg/kg
 906 mg/kg
2000 mg/kg
2823 mg/kg
 118 mg/kg
  80 mg/kg
 400 mg/kg
Non-lethal Acute Effects:
        Edema of lungs
        Convulsions
        Heart attack
        Vomiting
Chronic Toxicity

   U.S. Occupational Standard:  (air)  TWA 10 mg/m3


   Carcinogenicity:
Animal
 rat
 rabbit
 rat
 rat
 rat
 mouse
 wild bird
 mammal
Route
oral
skin
oral
skin
intiaperitoneal
intraperitoneal
oral
unre ported
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                    TLV:    ISmg/m3
                                       AIV-133

-------
Ruelene




                                     CHEMICAL NAME




    CAS Number:     299-86-5


    Chemical Name:   Methyl phosphoramidic acid, 4-tert-butyl-2-chlorophenyl methyl ester


    Synonyms:    Ruelene
                 4-t-Butyl-2-chlorophenyl-O-methyl methyl phosphoroamidate


    Molecular

      Formula:    C12H19aNO3P
                                         OCH
                                  _
                                  O - P
                                         NH - CH3
Chemical Properties


   Molecular Weight:     291.74


   Vapor Pressure:


   Boiling Point:


   Density:  T6


   Octanol/Water Parti-

    tion Coefficient:


Environmental Persistence


   BOD:


   Atmospheric Reactivity:
                                                    Physical State:    Solid


                                                    Vapor Density:


                                                    Melting Point:    61.8°C
                                                    Solubility:   0.5 gm/100mlH2Oat25 C
     Safety Hazard:
                                             AIV-134

-------
                                                                                 Ruelene
Annual U.S.
 Production:  2.0 x 106 Ibs.

Fraction of
 Dispersion:   Estimated as 1.0

Release Rate (million Ibs/yr):   2.0
                               PRODUCTION DATA
                     Consumption:

                     Fraction of Pro-
                       duction Lost:
               0.015
Acute Toxicity
        LD50
                                  TOXICITY DATA
. 770 mg/kg
 460 mg/kg
 770 mg/kg
 400 mg/kg
1000 mg/kg
 218 mg/kg
 100 mg/kg
Animal
 rat
 rat
 'rat
 rabbit
 guinea pig
 chicken
 wild bird
Route
oral
oral
unreported
oral.
oral
oral
oral
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 5 mg/m3


   Carcinogehicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                         Moderate irritant to eyes
                         Emesis
                     TLV:
                                       AIV-135

-------
Salicylic acid
                                     CHEMICAL  NAME
    CAS Number:     69-72-7

    Chemical Name:      Salicylic acid

    Synonyms:    o-Hydroxybenzoic acid
    Molecular
      Formula:    C7H6O3
                      OH
                           COOH
    Structure:
    Chemical Properties

       Molecular Weight:   138.13

       Vapor Pressure:   1 mm at 113.7°C

       Boiling Point:  211°C at 20 mm (sublimes)

       Density:   1.443 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:   2.32

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:   Solid

Vapor Density:   4.8

Melting Point:    158 to 161°C

Solubility:    Slightly (H2O)
            Very soluble (hot H2O)
    Safety Hazard:
           Fire-slight
           Explosion-slight
                                            AIV-136

-------
                                                                           Salicylic acid
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
35.0 x 106 Ibs. (acetosalicate)
1.0
Consumption:    35.2 x 106 Ibs.

Fraction of Pro-
 duction Lost:    0.03
Release Rate (million Ibs/yr):   35.9
                                  TOXICITY DATA
Acute Toxicity
       LD50
           891 mg/kg
           520 mg/kg
           700 mg/kg
           450 mg/kg
           991 mg/kg
           300 mg/kg
          1300 mg/kg
           900 mg/kg
           850 mg/kg
           500 mg/kg
  Non-lethal Acute Effects:
       Nausea
       Rapid pulse
       Skin eruptions
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
 rat
 mouse
 rat
 dog
 dog
 dog
 rabbit
 guinea pig
 guinea pig
 frog
 Route
oral
subcutaneous
subcutaneous
oral
intraperitoneal
subcutaneous
oral
intraperitoneal
subcutaneous
subcutaneous
                                TLV:
                                         AIV-137

-------
Silvex
                                      CHEMICAL NAME


    CAS Number:    93-72-1

    Chemical Name:     2-(2,4>S-Trichlor-phenoxy)propionic acid

    Synonyms:    2,4,5-TCPPA
    Molecular
      Formula:    C9h7Cl3O3
                          Cl
    Structure:   Cl
                   Cl
                                        __
                                        OH
    Chemical Properties

       Molecular Weight:    269.5

       Vapor Pressure:

       Boiling Point:

       Density:  l7640~

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:   Solid

Vapor Density:

Melting Point:   180.4 to 181.6°C
Solubility:   Slightly (140 ppm H2O at 25 C)
     Safety Hazard:
           Disaster hazard—dangerous-chlorides
                                             AIV-138

-------
                                                                                  Silvex

                               PRODUCTION DATA
Annual U.S.
 Production:  3 x 106 Ibs.                        Consumption:

Fraction of                                     Fraction of Pro-  _
 Dispersion:   Estimated as 1.0                       duction Lost:   0.015

Release Rate (million Ibs/yr):   3.0
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal              Route
       LDSo            375-1200 mg/kg            rat                 oral
                            650 mg/kg            rat                 oral
                            650 mg/kg            mammal             oral
                            650 mg/kg            mammal             unreported
       Low toxicity to man
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-139

-------
Sodium  acetate
                                    CHEMICAL  NAME
    CAS Number:    127-09-3

    Chemical Name:     Acetic acid, sodium salt

    Synonyms:


    Molecular
      Formula:    C2H3O2 * Na
                          O
    Structure:    CH3 - C
    Chemical Properties

       Molecular Weight:    83.06

       Vapor Pressure:

       Boiling Point:

       Density:    1.528

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:      45% of theoretical

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:   Solid

Vapor Density:

Melting Point:    324°C

Solubility:    Soluble (H2O)
                                           AIV-140

-------
                                                                   Sodium acetate
                              PRODUCTION DATA

Annual U.S.
 Production:   16.5 x 106 ibs. (1968)               Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                     duction Lost:  0.015

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage               Animal              Route
       LDSO              3530mg/kg           rat                oral
                         8000 mg/kg           mouse             subcutaneous
                          335 mg/kg           mouse             intravenous
       LDLo              3000 mg/kg           dog                intravenous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-141

-------
Sodium  benzoate
                                    CHEMICAL  NAME
    CAS Number:    532-32-1

    Chemical Name:     Benzole acid, sodium salt

    Synonyms:   Benzoate of soda
    Molecular
     Formula:   C7HSO2 -Na
    Structure:
                       O
    Chemical Properties

       Molecular Weight:   144.1

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:    Solid

Vapor Density:

Melting Point:

Solubility:   Soluble (H2O)
                                           AIV-142

-------
                                                                 Sodium  benzoate
                              PRODUCTION DATA

Annual U.S.
 Production:   ca. 6x10 Ibs. (1975)               Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:  0.015

Release Rate (million Ibs/yr):
                                 TOXICITYDATA

Acute Toxicity              Dosage              Animal              Route
       LDSO              4100 mg/kg            rat                oral
                         2000mg/kg            rabbit              oral
       LDLo              2000 mg/kg            rabbit .             subcutaneous
                         1400 mg/kg            guinea pig           intiapeiitoneal
                          100 mg/kg            frog               subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-143

-------
Sodium  carboxymethylcellulose
                                     CHEMICAL NAME


    CAS Number:   9004-324

    Chemical Name:    Cellulose, caiboxymethyl ether, sodium salt

    Synonyms:     Sodium carboxymethylcellulose          Cellulose gum
                  CMC                                CM cellulose
                  Sodium cellulose glycolate
    Molecular
      Formula:     (Exact composition unknown or undetermined)
    Structure:    A synthetic cellulose gum containing 0.4 to 1.5 sodium carboxymethyl group
                (-CH2COO Na) per glucose unit of the cellulose
     Chemical Properties
       Molecular Weight:  ca. 21,000 to 500,000         Physical State:     Solid

       Vapor Pressure:  < 0.6 mm at 25°C               Vapor Density:

       Boiling Point:    Decomposes                   Melting Point:
       Density:                                     Solubility:   Soluble (H26)

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
                                            AIV-144

-------
                                           Sodium  carboxymethylcellulose
                             PRODUCTION DATA

Annual U.S.
 Production:   69.0 x 106 Ibs.                   Consumption:   69.0 x 106 Ibs.

Fraction of                                   Fraction of Pro-
 Dispersion:    1-0                              duction Lost:     0.03

Release Rate (million Ibs/yr): 71.0
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
        Neoplasm:
          TDLo            8600 mg/kg (19 weeks)   rat   .            subcutaneous
   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                     AIV-145

-------
Sodium  chloroacetate
                                    CHEMICAL NAME
    CAS Number:    3926-62-3

    Chemical Name:  Chloroacetic acid, sodium salt

    Synonyms:



    Molecular
     Formula:    C2H2ClO2-Na
                          O
                          n
    Structure:     C1CH2 _  c _ o(-)Na<+>
    Chemical Properties

       Molecular Weight:    116.49                    Physical State:   Solid

       Vapor Pressure:                               Vapor Density:

       Boiling Point:    200°C (decomposes)            Melting Point:

       Density:                                     Solubility:  Soluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                                           AIV-146

-------
                                                          Sodium chloroacetate
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       LDSO               76 mg/kg             rat                oral
                         165 mg/kg             mouse             oral
                         109 mg/kg             mouse             intravenous
                          80 mg/kg             guinea pig           oral
       LDLo              100 mg/kg             mammal            oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-147

-------
Sodium formate
                                     CHEMICAL NAME
    CAS Number:    141-53-7

    Chemical Name:     Formic acid, sodium salt

    Synonyms:


    Molecular
      Formula:    CHO2' Na
                      O
    Structure:    HC
                            Na
                              <+>
    Chemical Properties

       Molecular Weight:    68.01

       Vapor Pressure:

       Boiling Point:    253°C (decomposes)

       Density:   l.92at20°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:     42% of theoretical

       Atmospheric Reactivity:
Physical State:   Solid

Vapor Density:

Melting Point:    253°C

Solubility:    Soluble (440 gm/1 H2O)
    Safety Hazard:
           Fire-slight
                                           AIV-148

-------
                                                                   Sodium formate
                              PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
32.0 x 106 Ibs.
0.70
Consumption:   32.0 x 106 Ibs.

Fraction of Pro-
 duction Lost:  0.015
Release Rate (million Ibs/yr):  22.9
                                 TOXICITY DATA
Acute Toxicity
       LD
         Lo
            Dosage
            807 mg/kg
           2500 mg/kg
           4000 mg/kg
           3000 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
 mouse
 mouse
 dog
 dog
                               TLV:
 Route
intravenous
unreported
oral
intravenous
                                      AIV-149

-------
Sodium  phenate
                                     CHEMICAL NAME
    CAS Number:    139-02-6

    Chemical Name:     Phenol, sodium salt
    Synonyms:
    Molecular
      Formula:
Sodium phenolate
Sodium carbolate
Sodium phenylate

C6H5NaO
    Structure:
    Chemical Properties

       Molecular Weight:    116.0

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:
                                Physical State:      Solid

                                Vapor Density:

                                Melting Point:

                                Solubility:      Soluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Decomposed by CO2 of the air
    Safety Hazard:
                                            AIV-150

-------
                                                                Sodium phenate
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                             PRODUCTION DATA
            Consumption:

            Fraction of Pro-
              duction Lost:
Acute toxicity
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
TOXICITY DATA

             Animal
             TLV:
Route
                                     AIV-151

-------
Sorbic  acid
                                      CHEMICAL NAME
    CAS Number:    11044-1

    Chemical Name:     Sorbic acid

    Synonyms:    2.4-Hexadienoicacid
                 1,3-Pentadiene-l-carboxylic acid
                 2-Propenylacrylic acid
    Molecular
      Formula:    C6H8O2
                                         O
                           H
    Structure:
CH3
  \
                             \
 	
c = c
OH
                      C = C
                    _/     \_
                    H       H
                                  (trans-trans)

    Chemical Properties   -(tian&.tians)

       Molecular Weight:    112.12

       Vapor Pressure:   <0.01 mm at 20°C

       Boiling Point:    228°C (decomposes)

       Density:   1.204 at 19°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
                                  Physical State:    Solid

                                  Vapor Density:   3.87

                                  Melting Point:    134.5°C

                                  Solubility:    Soluble (2.5 gm/1 H2O)
    Environmental Persistence

       BOD:     70% of theoretical after 10 days at 20°C

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
           Fire—slight
                                             AIV-152

-------
                                           Sorbic acid
PRODUCTION DATA
Annual U.S.
 Production:
               40 x 10 Ibs.
Fraction of
 Dispersion:  0-^0

Release Rate (million Ibs/yr):  20.6
               Consumption:    40 x 106 Ibs.

               Fraction of Pro-
                 duction Lost:   0.015
  TOXICITY DATA
Acute Toxicity
       LDLo
       LDSO
                          Dosage
                         5000 mg/kg
                         7400 mg/kg
                                              Animal
                                               human
                                               rat
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:
       TDLo

   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                         2600 mg/kg (65 weeks)    (rat
               TLV:
                                    Route
                                   unreported
                                   oral
                                   subcutaneous
        AIV-153

-------
Sorbitol
                                     CHEMICAL NAME
    CAS Number:   50-704

    Chemical Name:    D-Glucitol

    Synonyms:  Hexahydric alcohol
               Sotbol

    Molecular
      Formula:  C6H14O6
                           OH H OH OH
                            I    I   I    I
    Structure:    HO - CH2 -C-C-C-C- CH2 - OH
                            i    r  i    i
                            H OH  H  H
    Chemical Properties

       Molecular Weight:   182.18

       Vapor Pressure:    Negligible

      . Boiling Point:   295°C at 3.5 mm

       Density:  1.489 at 200C/40C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:  Solid

Vapor Density:

Melting Point:  110 to 112°C (anhydrous)

Solubility:    Very soluble (2350 gm/1
                                           AIV-154

-------
                                                                              Sorbitol
                              PRODUCTION DATA
Annual U.S.
 Production:   84.1 x 106 Ibs. (1968)

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):    52.2
                   Consumption:

                   Fraction of Pro-
                    duction Lost:  0.015
Acute Toxicity
      TOXICITY DATA

Dosage               Animal
Route
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:


   Mgtagenicity:

   Teratogenicity:

   Other Chronic Effects:
                   TLV:
                                      AIV-155

-------
Styrene monomer
                                     CHEMICAL  NAME
    CAS Number:   100-42-5

    Chemical Name:   Styrene

    Synonyms:  Phenylethylene
               Vinyl benzene

    Molecular
      Formula:  C8H8
Cinnamine
    Structure:    4    /}- CH = CH2
    Chemical Properties

       Molecular Weight:  104.14

       Vapor Pressure:   6.05 mm at 25°C

       Boiling Point:  146°C at 760 mm

       Density:    0.9045 at 25°C/25°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence
       BOD:   87% of theoretical after 20 days at 20° C
               Total theoretical oxygen demand = 3.1 gm/gm
       Atmospheric Reactivity:  Reacts with oxidizing materials
    Safety Hazard:
         Fire-moderate
         Disaster hazard—dangerous—toxic fumes
 Physical State:    Liquid

 Vapor Density:

 Melting Point:    -30.63°C

 Solubility:  Insoluble (H2O)
                                            AIV-156

-------
                                                                  Styrene  monomer
                               PRODUCTION DATA
Annual U.S.
 Production:  4394.0 x 106 Ibs. (1975)

Fraction of
 Dispersion:   °

Release Rate (million Ibs/yr):   89.1
                        Consumption: 4394.0 x 106 Ibs.

                        Fraction of Pro-
                         duction Lost:   °-015
                                 TOXICITY DATA
Acute Toxicity
     LDSO
    Dosage
 5000 mg/kg
   216 mg/kg
10,000 ppm (30 months)
 5,000 ppm
10,000 ppm
                     Animal
                    rat
                    mouse
                    human
                    rat
                    mouse
12 gm/m^ (14 hours)   guinea pig
  Route
oral
oral
inhalation
inhalation
inhalation
inhalation
Non-lethal Acute Effects:
     Irritant
        TCLO            600 ppm              human              inhalation
     Central nervous system
        TCL0            376 ppm              human              inhalation
     Glandular
        TCLO             20 mg/m3            woman              inhalation
     Lachrymation and violent itching of the eyes
     Weakness            ~
     Stupor
     Incoordination
     Tremors
     Unconsciousness

Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 100 ppm
                                Ceiling concentration 200 ppm
                                 Peak concentration  600 ppm/5 minutes/ 3 hours

   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                     ,   TLV:   100 ppm
                                        AIV-157

-------
Succinic acid
                                      CHEMICAL  NAME


    CAS Number:  110-15-6

    Chemical Name:   Succinic acid

    Synonyms:     Ethylene succinic acid               Butanedioic acid
                  Ethylene dicarboxylic acid

    Molecular
      Formula:   C4H6O4
                           o
                         I.
                  H,C - C
    Structure:
                  H2C-C

                         ' 0
H2C - C - OH
       I
H2C - C - OH
    Chemical Properties

       Molecular Weight:  118.09                       Physical State:    Solid

       Vapor Pressure:                                 Vapor Density:

       Boiling Point:  235°C (decomposes)               Melting Point:  188°C

       Density: 1.564 at 15°C/4°C                      Solubility:  Slightly (H2O)
                                                                Very soluble (hot H2O)
       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
     Safety Hazard:
          Fire-slight
                                             AIV-158

-------
                                                                      Succinic acid
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                              PRODUCTION DATA
                      Consumption:

                      Fraction of Pro-
                       duction Lost:
                                TOXICITY DATA
Acute Toxicity
   Dosage
2000 mg/kg
 Animal
frog
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                      TLV:
   Route
subcutaneous
                                      AIV-159

-------
Succinonitrile
                                     CHEMICAL  NAME
    CAS Number:   110-61-2

    Chemical Name:    Succinonitrile

    Synonyms:  Butanedinitrile
               Ethylenedicyanide

    Molecular
      Formula:  C4H4N2
    Structure:
H2C-C = N
   I
H2C-C =
    Chemical Properties

       Molecular Weight:     S0.09

       Vapor Pressure: 2 mm at 100°C

       Boiling Point:   267°C  at 760 mm

       Density:  1.022 at 20°C

       Octanol/Water Parti-
        tion Coefficient:     0-35

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
                                   Physical State:     Solid

                                   Vapor Density: 270°C

                                   Melting Point:  57 to 57.5°C

                                   Solubility:  Very soluble (H2O)
    Safety Hazard:
         Disaster hazard-dangerous-toxic fumes of cyanides
                                            AIV-160

-------
                                                                       Succinonitrile
                              PRODUCTION DATA

Annual U.S.
 Production:                                    Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
     LD50                 100 mg/kg          rat                intiaperitoneal
     LDLo                 150 mg/kg          dog                unreported
                            36 mg/kg          rabbit              unreported
                          2200 mg/kg        .  pigeon             unreported
                          1000 mg/kg          frog               subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-161

-------
Sulfanilic  acid
                                     CHEMICAL  NAME
    CAS Number:    88-21-1

    Chemical Name:   o-Aminobenzenesulfonic acid

    Synonyms:    Sulfanilic acid
                 Orthanilic acid
    Molecular
     Formula:
C6H7N03S-HiO
                      NH-.
    Structure:
         SO3H-H2O
    Chemical Properties

       Molecular Weight:   191.2

       Vapor Pressure:

       Boiling Point:

       Density:   1.485 at 25°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                                   Physical State:    Solid

                                   Vapor Density:

                                   Melting Point:    288°C (decomposes)

                                   Solubility:    Slightly (hot H2O)
    Safety Hazard:
           Disaster hazard-dangerous-toxic fumes-NOx and SOX
                                            AIV-162

-------
                                                                      Sulfanilic  acid
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION DATA
                   Consumption:

                   Fraction of Pro-
                     duction Lost:
Acute Toxicity


Non-lethal Acute Effects:
       Slight irritation
       Low toxicity
      TOXICITY DATA

Dosage               Animal
Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                   TLV:
                                       AIV-163

-------
Sulfolane
                                      CHEMICAL  NAME
    CAS Number:   126-334

    Chemical Name:   Tetrahydrothiophene-l,l-dioxide

    Synonyms:   Sulfolane
                Cyclocyclic tetramethylene sulfone
                Cyclo tetiamethylene sulfone
    Molecular
      Formula:   C4HgO2S
Tetramethylene sulfone.
    Structure:
    Chemical Properties

       Molecular Weight:     120.18

       Vapor Pressure:   0.01 mm at 20°C

       Boiling Point:    285°C

       Density:  1.261 at 30°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
          Reacts slowly with ROj and 63
          Activity toward OH: t^ = 2 days



    Safety Hazard:
Physical State:     Liquid

Vapor Density:

Melting Point:  27°C

Solubility:  Infinite (H2O)
                                            AIV-164

-------
                                                                             Sulfolane
Annual U.S.
 Production:   35.0 x 106 Ibs.

Fraction of
 Dispersion:    Estimated as 1.0

Release Rate (million Ibs/yr): 35.5
      PRODUCTION DATA


                     Consumption:   35.0 x 106 Ibs.

                     Fraction of Pro-
                       duction Lost:     0.015
Acute Toxicity
      LDSO
                                 TOXICITY DATA
1540 mg/kg
1900 mg/kg
3180 mg/kg
 Animal
rat
mouse
rabbit
  Route
oral
oral
skin
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                     TLV:
                                       AIV-165

-------
Sulfosuccinic, bis(2-ethylhexyl) ester, sodium salt
                                   CHEMICAL  NAME

    CAS Number:   577-11-7
    Chemical Name:     Sulfobutanedioic acid,l,4-bis(2-ethylhexyl)ester, sodium salt
    Synonyms:

    Molecular
     Formula:    C20H37O7S-Na
                              C2H5
O
              o
             • II
C2H5
                               I             ii            • ii             I
    Structure:    CH3 - (CH2)3 - CH - CH2 - O - C - CH2 - CH - C - O - CH2 - CH - (CH2)3 - CH3
                                                     I
                                                    SO3--Na+
    Chemical Properties
       Molecular Weight:    445.64
       Vapor Pressure:
       Boiling Point:
       Density:
       Octanol/Water Parti-
        tion Coefficient:
    Environmental Persistence
       BOD:
       Atmospheric Reactivity:
    Safety Hazard:
      Physical State:
      Vapor Density:
      Melting Point:
      Solubility:
                                         AIV-166

-------
                  Sulfosuccinic, bis(2-ethylhexyl) ester, sodium  salt
                             PRODUCTION DATA
Annual U.S.
 Production:    12.4 x 106 Ibs.

Fraction of
 Dispersion:   1.0

Release Rate (million Ibs/yr):  12.8
                   Consumption:   12.4 x 106 Ibs.

                   Fraction of Pro-
                    duction Lost:   0.03
                               TOXICITY DATA
Acute Toxicity
      LD50
 Dosage
1900 mg/kg
4800 mg/kg
  60 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
Animal
rat
mouse
mouse
                   TLV:
 Route
oral
oral
intravenous
                                    AIV-167

-------
Sutan
                                    CHEMICAL NAME


    CAS Number:    2008-41-5

    Chemical Name:    Bis(2-methylpropyl)carbamothioic acid, S-ethyl ester

    Synonyms:   S-Ethyldiisobutylthiocarbamate


    Molecular
     Formula:   CuH23NOS
                                          CH3
                                           I
                            O      CH2 - CH - CH3
                            n     /
    Structure:      CH3CH2S - C - N
                                    CH2 - CH - CH3
                                          CHq
    Chemical Properties

       Molecular Weight:   217.41

       Vapor Pressure:  13 x 10"3 mm at 25°C

       Boiling Point:

       Density:   0.9402 at 25°C/25°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:   Liquid

Vapor Density:

Melting Point:

Solubility:   45 ppm H2O at 22°C
    Safety Hazard:
                                           AIV-168

-------
                                                                                  Sutan

                              PRODUCTION DATA
Annual U.S.
 Production:    6.0 x 10 Ibs.                     Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:    Estimated as 1.0                    duction Lost:   0.015

Release Rate (million Ibs/yr):  6.0
                                 TOXICITY DATA

Acute Toxicity               Dosage              Animal              Route
       LD5o              5366 mg/kg           rat                oral
                         4000mg/kg           rat                oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-169

-------
TBA
                                       CHEMICAL  NAME
    CAS Number:   50-31-7

    Chemical Name:    2,3,6-Ttichlotobenzoic acid

    Synonyms:   2,3,6-TCB
                 2,3,6-TBA
    Molecular
      Formula:
    Structure:
                         Cl
     Chemical Properties

       Molecular Weight:  225.46

       Vapor Pressure:  Negligible

       Boiling Point:

       Density:

       Octanol/Water Parti-
         tion Coefficient:
Physical State:   Solid

Vapor Density:

Melting Point:   124 to 125°C (pure compound)
               87 to 99°C (commercial mixture)
Solubility:   Slightly soluble (0.84 gm/100 ml H2O)
     Environmental Persistence

        BOD:

        Atmospheric Reactivity:   Relatively stable to ultraviolet decomposition
     Safety Hazard:
                                              AIV-170

-------
                                                                                      TBA
Annual U.S.
 Production:

Fraction of
 Dispersion:
              2.0 x 10° Ibs.
                               PRODUCTION DATA
Consumption:
              Estimated as 1.0

Release Rate (million Ibs/yr):  2.0
Fraction of Pro-
 duction Lost:  0.015
Acute Toxicity
      LDSO
                                  TOXICITY DATA
                           Dosage
                         1644 mg/kg
                          650 mg/kg
                         1000 mg/kg
                          615 mg/kg
                         1500 mg/kg
                          812 mg/kg
                         1218 mg/kg
                          700 mg/kg
 Animal
 rat
 rat
 rat
 mouse
 mouse
 rabbit
 guinea pig
 mammal
  Route
oral
oral
intraperitoneal
oral
subcutaneous
oral
oral
unreported
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                               TLV:
                                       AIV-171

-------
TCA
                                     CHEMICAL  NAME
     CAS Number:   76-03-9

     Chemical Name:    Trichloroacetic acid

     Synonyms:   TCA
    Molecular
      Formula:   C2HC13O2
                      Cl   O
                       I   ii
    Structure:     Cl - C - C - OH
                       I
                      Cl
     Chemical Properties

       Molecular Weight:   163.38

       Vapor Pressure:  5 mm at 77°C

       Boiling Point:  197.55°Cat760mm

       Density:   1.62 at 25°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:  Solid

Vapor Density:

Melting Point:  55to58°C

Solubility:   Very soluble (H2O)
     Safety Hazard:
                                            AIV-172

-------
                                                                                     TCA
Annual U.S.
 Production:

Fraction of
 Dispersion:
              1.0xl06lbs.
              Estimated as 1

Release Rate (million Ibs/yr):  1-0
                               PRODUCTION DATA
  Consumption:
  Fraction of Pro-
    duction Lost:  0.015
Acute Toxicity
      LD50
      LDLo
                                 TOXICITY DATA

                                               Animal
                          3320 mg/kg
                          500 mg/kg
rat
mouse
  Route
oial
intraperitoneal
 Non-lethal Acute Effects:
      May cause skin bums upon prolonged contact
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
         Irritant to nose and throat
                                               TLV:
                                       AIV-173

-------
Terephthalic acid
                                     CHEMICAL  NAME
    CAS Number:    100-21-0

    Chemical Name:   Teiephthalic acid

    Synonyms:    p-Phthalic acid
                 TPA
                 Benzene-p-dicar boxy lie acid
    Molecular
      Formula:    C8H6O4
    Structure:
                 O
OH
    Chemical Properties

       Molecular Weight:    166.14

       Vapor Pressure:   Negligible

       Boiling Point:     Sublimes

       Density:   1.51

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
                            Physical State:   Solid

                            Vapor Density:

                            Melting Point:   >300° sublimes without melting

                            Solubility:   Insoluble (H2O)
                                            AIV-174

-------
                                                                Terephthalic  acid
                              PRODUCTION DATA
Annual U.S.
 Production:    4644.1 x 106 Ibs. (1975)

Fraction of
 Dispersion:    0

Release Rate (million Ibs/yr):   28.9
                    Consumption:     4644 x 106 Ibs.

                    Fraction of Pro-
                     duction Lost:   0.015
                                TOXICITY DATA
Acute Toxicity
       LDSO
       LD10
1430 mg/kg
 767 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
Animal
mouse
dog
 Route
intraperitoneal
intravenous
                    TLV:
                                     AIV-175

-------
Termik
                                     CHEMICAL  NAME


    CAS Number:   116-06-3

    Chemical Name:     2-Methyl-2(methylthio)propionaldehyde-O-(methyl-caibamoyl)oxime

    Synonyms:      Termik
                   Aldicaib
    Molecular
      Formula:
C7H14N202S
                           CH,
    Structure:      CH3-S-C-CH = N-O-C

                           CH,
                                               O
     Chemical Properties

       Molecular Weight:  190.1

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                           \
                            N-CH3

                            H
                                 Physical State:

                                 Vapor Density:

                                 Melting Point:

                                 Solubility:
Solid
100°C
     Safety Hazard:
                                            AIV-176

-------
                                                                                   Termik
Annual U.S.
 Production:

Fraction of
 Dispersion:
              2.0 x 10" Ibs.
              Estimated as 1.0

Release Rate (million Ibs/yr): 2.0
                               PRODUCTION DATA
  Consumption:

  Fraction of Pro-
   duction Lost:
0.015
Acute Toxicity
      LDSO
                                  TOXICITY DATA
                           Dosage
                            0.93 mg/kg
                            5    mg/kg
                            1    mg/kg
                         2500    //g/kg
                          930
                          300
                         1400    mg/kg
                         4440    Mg/kg
                          666    Mg/kg
   Animal
rat
rabbit
rat
rat
rat
mouse
rabbit
duck
rat
     Route
 oral
 skin
 oral
 skin
 unreported
 oral
 skin
 oral
 subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                               TLV:
                                        AIV-177

-------
1,1,1,  2-Tetrachloro-2, 2-difluoroethane
                                   CHEMICAL  NAME



    CAS Number:   76-12-0


    Chemical Name:    l,l,2,2-Tetiachloro-l,2-difluoroethane


    Synonyms:   Tetrachlotodifluoroethane
    Molecular
     Formula:
    Structure:
                 a a
                  i   i
             F-C-C-F
                  I  .1
                 a a
                                                  Physical State:  Liquid

                                                  Vapor Density:  7.03

                                                  Melting Point:  25°C


                                                  Solubility:   Insoluble (H2O)
Chemical Properties

   Molecular Weight:  203.83

   Vapor Pressure:  52.53 mm at 25°C


   Boiling Point:    93°C at 760 mm

   Density:  1.6447 at 25°C/4°C

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
      Stable in lower atmosphere
    Safety Hazard:
          Disaster hazard—dangerous—toxic fumes of chlorides and fluorides
                                         AIV-178

-------
                            1,  1,  1, 2-Tetrachioro-2, 2-difluoroethane
                            PRODUCTION DATA

Annual U.S.
 Production:                                 Consumption:

Fraction of                                   Fraction of Pro-
 Dispersion:                                   duction Lost:

Release Rate (million Ibs/yr):
                              TOXICITY DATA

Acute Toxicity              Dosage             Animal              Route
      LCSO            10,000 ppm (7 hours)     rat               inhalation
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                   AIV-179

-------
  , 2, 2-Tetrachloro-l, 2-difluoroethane
                                CHEMICAL  NAME
CAS Number:   76-12-0

Chemical Name:    1,1,2,2-Tetrachloro-l, 2-difluoroethane

Synonyms:   1 ,2-Difluoro-l ,1 ,2 ,2-tetrachloroethane     Freon 112
            sym-Tetrachloiodifluoroethane           Genetronll2
            F-112
Molecular
 Formula:
Structure:
   Cl  Cl
    I   I
F-C-C-F
    I   I
    Cl  Cl
Chemical Properties

   Molecular Weight:   208.83

   Vapor Pressure:

   Boiling Point:   93°C at 760 mm

   Density:   1.6447 at 25°C/4°C

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
       Stable in lower atmosphere
                                   Physical State:   Solid or liquid

                                   Vapor Density:

                                   Melting Point:   25°C

                                   Solubility:   Insoluble (H2O)
Safety Hazard:
                                       AIV-180

-------
                            1, 1, 2,  2-Tetrachloro-l, 2-difluoroethane
                            PRODUCTION DATA

Annual U.S.
 Production:                                Consumption:

Fraction of                                  Fraction of Pro-
 Dispersion:                                   dilution Lost:

Release Rate (million Ibs/yr):
                              TOXICITY DATA

Acute Toxicity             Dosage              Animal             Route
Chropic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                    AIV-181

-------
Tetrachloronaphthalene
                                    CHEMICAL  NAME


    CAS Number:     605-36-7

    Chemical Name:   l,2,3,4-Tetrachloro-l,2,3,4-tetrahydronaphthalene

    Synonyms:


    Molecular
     Formula:     C10H8CU
    Structure:
                             Cl
                            a
                       a
Solid
                                                   Physical State:

                                                   Vapor Density:

                                                   Melting Point:  182°C

                                                   Solubility:
Chemical Properties

   Molecular Weight:     269.99

 •  Vapor Pressure:

   Boiling Point:

   Density:

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
    Safety Hazard:
         Disaster hazard-dangerous; when heated to decomposition produces toxic fumes
                                           AIV-182

-------
                                                      Tetrachloronaphthalene
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                             PRODUCTION DATA
                  Consumption:

                  Fraction of Pro-
                    duction Lost:
Acute Toxicity
Non-lethal Acute Effects:
     Systemic effects
        TCLo
      TOXICITY DATA

Dosage              Animal
 3mg/m3
human
Chronic Toxicity

   U.S. Occupational Standard: (air) TWA 2 mg/m3 (skin)



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                   TLV:
                    Route
inhalation
                                      AIV-183

-------
Tetrachlorophthalic  anhydride
                                    CHEMICAL NAME
    CAS Number:      117-08-8

    Chemical Name:    Tetrachlorophthalic anhydride,


    Synonyms:
    Molecular
      Formula:  C8C14O3
    Structure:
             •a
                  a
     Chemical Properties

       Molecular Weight:   285.90

       Vapor Pressure:

       Boiling Point:   371°C (sublimes)

       Density:

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
Physical State:  Solid

Vapor Density:


Melting Point:  255 to 256.5°C


Solubility:   Slightly (decomposes in hot H2O)
                                          AIV-184

-------
                                            Tetrachlorophthalic anhydride
                            PRODUCTION DATA

Annual U.S.
 Production:                                 Consumption:

Fraction of                                   Fraction of Pro-
 Dispersion:                                   duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITY DATA

Acute Toxicity              Dosage             Animal             Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                             fLV:

   Other Chronic Effects:
                                    AIV-185

-------
Tetraethyl lead
                                     CHEMICAL  NAME
    CAS Number:    78-00-2

    Chemical Name:    Tetraethylplumbane

    Synonyms:   Tetraethyl lead
                TEL

    Molecular
      Formula:   C8H20Pb
                           CH2 - CH3
    Structure:   CH3 - CH2 - Pb - CH2 - CH3

                           CH2

                           CH2

    Chemical Properties

       Molecular Weight:   323.44

       Vapor Pressure:  1 mm at 28.4°C

       Boiling Point:   200°C (decomposes)

       Density:  1.659 at 11°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
          WithO3: tw= 2-3 days
          With RC>2: slow to react in water
          With OH :tv4= 2-3 days
    Safety Hazard:
          Fire-moderate
Physical State:  Liquid

Vapor Density:

Melting Point:   -136.8°C

Solubility:    Insoluble (2 x 10^g/l H2O)
                                           AIV-186

-------
                                                                       Tetraethyl  lead
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:  1 -0
353.0 x 106 Ibs. (1973)
Consumption:    280.4 x 106 Ibs.

Fraction of Pro-
 duction Lost:   0.015
Release Rate (million Ibs/yr):  14.6
                                  TOXICITY DATA
Acute Toxicity
       LD50
            Dosage
            15 mg/kg
            17 mg/kg
            10 mg/kg
            31 mg/kg
            86 mg/kg
           500 mg/kg
            23 mg/kg
           990 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:
      TDLo                86 mg/kg (21 days)

   Mutagenicity:    No information

   Teratogenicity:   Positive-rat-oral

   Other Chronic Effects:
      Metabolic disturbances
      Nervous system disorders
      Inhibition of DNA synthesis
      Decreased ACHase activity
 Animal
 rat
 rat
 rat
 rat
 mouse
 dog
 rabbit
 guinea pig
 Route
parenteral
oral
intraperitoneal
intravenous
subcutaneous
skin
intravenous
skin
                                 mouse
                                                     subcutaneous
                                 TLV:  0.0117mg/m3
                                        AIV-187

-------
Tetrahydrofuran
                                      CHEMICAL  NAME
     CAS Number:   109-99-9

     Chemical Name:   Tetrahydrofuran

     Synonyms:  Cyclotetramethylene oxide
                1,4 Epoxy-butone
                Hydrofuron
     Molecular
      Formula:  C4H8O
Butane a,£-oxide
Butylene oxide
Diethylene oxide
Oxacyclopentane
Tetramethylene oxide
Oxolane
Furanidine
     Structure:
     Chemical Properties

        Molecular Weight:  72.10

        Vapor Pressure:  143 mm at 20°C

        Boiling Point:   67°C

        Density:  0.8892 at 20°C/4°C

        Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

        BOD:

        Atmospheric Reactivity:  Forms peroxides readily
     Safety Hazard:
          Fire—dangerous
          Explosion-moderate
         Physical State:  Liquid

         Vapor Density:  2.5

         Melting Point:   -65° C

         Solubility:   Soluble (H2O)
                                             AIV-188

-------
                                                                   Tetrahydrofuran
                              PRODUCTION DATA

Annual U.S.
 Production:    59.0xl06lbs.                     Consumption:  59.0xl06lbs.
              (90 x 106 Ibs., 1975 estimate)
Fraction of                                     Fraction of Pro-
 Dispersion:    °-70                              duction Lost: 0-015

Release Rate (million Ibs/yr): 42.2
                                 TOXICITY DATA

Acute Toxicity               Dosage              Animal               Route
     LDLo              3000mg/kg           rat                oral
                         500 ing/kg           rat                intraperitoneal

Non-lethal Acute Effects:
     Narcotic
     Irritant to eyes, skin and respiratory tract
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA200ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:  200 ppm

   Other Chronic Effects:
                                       AIV-189

-------
Tetrahydronaphthalene
                                    CHEMICAL NAME
    CAS Number:   119-64-2

    Chemical Name:   1,2,3,4-Tetrahydronaphthalene

    Synonyms:  tetralin
    Molecular
     Formula:   C10H12
    Structure:
    Chemical Properties

       Molecular Weight:     132.21                   Physical State:  Liquid

       Vapor Pressure:  l mm at 38.0°C                 Vapor Density:  4.55

       Boiling Point:    207.57°Cat 760 mm             Melting Point:  -35.79°C

       Density:  0.9702 at 20°C/4°C                   Solubility:  Insoluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
          Fire—moderate
                                          AIV-190

-------
                                                         Tetrahydronaphthalene
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of          .                          Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
     LDSO              2860 mg/kg            rat                 oral
     LDio               275 ppm (8 hours      guinea pig           inhalation
                         for 17 days)

Non-lethal Acute Effects:
     Local irritant
     Narcotic in high concentrations
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
     Cataracts and kidney injury
                                      AIV-191

-------
Tetrahydrophthalic anhydride
                                    CHEMICAL  NAME
     CAS Number:   85-43-8

     Chemical Name:    4-Cyclohexene-l,2-dicarboxylie acid

     Synonyms:  Tetrahydrophthallic anhydride


     Molecular
      Formula:  C8H8O3


                        O
    Structure:
                        O

     Chemical Properties

       Molecular Weight:     152.14

       Vapor Pressure:    <0.01 mm at 20°C

       Boiling Point:   195°Cat50mm

       Density:  1.375 at 25°C/20°C

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
Physical State:     Solid

Vapor Density:    5.25

Melting Point:

Solubility:   Insoluble (H2O)
                                           AIV-192

-------
                                             Tetrahydrophthalic anhydride
                             PRODUCTION DATA

Annual U.S.
 Production:                                 Consumption:

Fraction of                                   Fraction of Pro-
 Dispersion:                                   duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
                       500 mg/kg            mouse             intraperitoneal
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                    AIV-193

-------
Tetramethylethylenediamine
                                    CHEMICAL NAME


    CAS Number:      110-18-9

    Chemical Name:    N,N ,N ',N '-Tetramethylethylenediamine

    Synonyms:  N ,N,N',N'-Tetramethyl-l ,2-diaminoethane
    Molecular
      Formula:  C6Hi6N2
                    CH,
              CH3- N
N - CH,
    Structure:
                       c  =  c
    Chemical Properties

       Molecular Weight:  116.24

       Vapor Pressure:

       Boiling Point:  121 to 122°C

       Density:   0.7765 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                  Physical State:   Liquid

                  Vapor Density:

                  Melting Point: -55.1°C

                  Solubility:   Soluble (H2O)
                                           AIV-194

-------
                                              Tetramethylethylenediamine
                            PRODUCTION DATA

Annual U.S.
 Production:                                Consumption:

Fraction of                                  Fraction of Pro-
 Dispersion:                                   duction Lost:

Release Rate (million Ibs/yr):
                              TOXICITY DATA

Acute Toxicity              Dosage             Animal              Route
     LDLo              1580 mg/kg           rat                oral .
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                    AIV-195

-------
Tetramethyl  lead
                                    CHEMICAL  NAME
    CAS Number:   75-74-1

    Chemical Name:   Tetramethyl plumbane

    Synonyms:  Tetramethyl lead
               Lead tetramethyl  '
               TML
    Molecular
     Formula:
                    CH,
                     I
    Structure:  CH3 - Pb - CH3

                    CH3



    Chemical Properties

       Molecular Weight:  267.33                       Physical State:  Liquid

       Vapor Pressure: 6.0 mm at 10°C                  Vapor Density:    9.2

       Boiling Point:  liO°CatlOmm                 Melting Point:  27.5°C

       Density:  1.995                                Solubility:   Insoluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts vigorously with oxidizing materials
    Safety Hazard:
         Fire-dangerous
         Explosion-moderate
                                           AIV-196

-------
                                                                   Tetramethyl lead
                               PRODUCTION DATA

Annual U.S.
 Production:    972.5 x 106 Ibs.                    Consumption:  900 x 106 Ibs.
              (organo lead compounds)                          (oigano lead compounds)
Fraction of                                     Fraction of Pro-
 Dispersion:    1-0                                duction Lost: 0.015

Release Rate (million Ibs/yr): 14.6 (tetramethyl lead)
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
     LDSO              109mg/kg             rat  .               oral
                        .105 mg/kg             rat                 parenteral
     LDLo                73 mg/kg             rat                 intraperitoneal
                          90 mg/kg             rabbit              intravenous
     Can be fatal if swallowed
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 90 Mg/m3 (skin)



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:   90jig/m3

   Other Chronic Effects:
                                      AIV-197

-------
Tetramethyl succinonitrile
                                    CHEMICAL  NAME
    CAS Number:   3333-52-6

    Chemical Name:    Tetramethyl succinonitrile

    Synonyms:  TSN
    Molecular
      Formula:  C8H12N2
    Structure:
                     C=N
CH3-C-CH3
      I
CH3 - C - CH3
    Chemical Properties

       Molecular Weight:   136.20

       Vapor Pressure:

       Boiling Point:

       Density:  1.070

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
                                  Physical State:    Solid

                                  Vapor Density:

                                  Melting Point:   170.5 to 171.5°C

                                  Solubility:
                                          AIV-198

-------
                                                  Tetramethyl succinonitrile
                             PRODUCTION DATA

Annual U.S.
 Production:                                  Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
                          60 ppm             rat                inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (aii) TWA  3 mg/m3 (skin)



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-199

-------
Tetranitromethane
                                    CHEMICAL  NAME
    CAS Number:   509-14-8

    Chemical Name:   Tetranitromethane

    Synonyms:
    Molecular
      Formula:  CN4Og
                      NO2
    Structure:    O2N - c - NO2
                      NO2
    Chemical Properties

       Molecular Weight:  196.03                      Physical State:     Liquid

       Vapor Pressure:   1 mm at 22.7°C               Vapor Density:

       Boiling Point:   126°C                         Melting Point:  14.2°C

       Density:    1.6380 at 20°C/4°C                 Solubility:  Insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:                                       •

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts with oxidizing materials
     Safety Hazard:
          Fire-dangerous
          Explosion-severe
          Disaster hazard-severe-toxic fumes-NOx
                                            AIV-200

-------
                                                               Tetranitrom ethane
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                              PRODUCTION DATA
                     Consumption:

                     Fraction of Pro-
                      duction Lost:
                                TOXICITY DATA
Acute Toxicity
      LCLo
      LDLo
  Dosage
 33 ppm (6 hours)
500 rag/kg
Animal
rat
mammal
  Route
inhalation
inhalation
 Non-lethal Acute Effects:
      Irritant to eyes and respiratory passages
    .  Pulmonary edema
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 1 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
      Liver damage
      Kidney damage
                     TLV:  1ppm
                                      AIV-201

-------
Tetrapropylene
                                    CHEMICAL  NAME
    CAS Number:   112-114

    Chemical Name:   1-Dodecene

    Synonyms:  a-Dodecylene
    Molecular
      Formula:  ci2H24
    Structure:   CH3(CH2)9CH = CH2
    Chemical Properties

       Molecular Weight:     168.33

       Vapor Pressure:

       Boiling Point:  213.4°C at 760mm

       Density:  0.7584 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:    Liquid

Vapor Density:

Melting Point:  -35.23°C

Solubility:  Insoluble (H2O)
                                          AIV-202

-------
                                                                  Tetrapropylene
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                             PRODUCTION DATA
             Consumption:

             Fraction of Pro-
              duction Lost:
Acute Toxicity
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
TOXICITY DATA

             Animal
Route
             TLV:
                                     AIV-203

-------
Tetryl
                                      CHEMICAL  NAME
    CAS Number:  47945-8

    Chemical Name:   N-Methyl-N,2,4,6- tetranitroaniline

    Synonyms:   Tetryl
                Tetralite
                Trinitrophenylmethylnitramine
    Molecular
      Formula:   C7H5NSO8
Nitramine
    Structure:
                            NO-,
                                  CH,
                            NO2      3
    Chemical Properties

       Molecular Weight:  287.15

       Vapor Pressure:

       Boiling Point:  Explodes at 187°C

       Density:     1.57atl9°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
Physical State:     Solid

Vapor Density:

Melting Point:  !31tol32°C

Solubility:  Insoluble (H2O)
     Safety Hazard:
          Fire-dangerous
          Explosion-severe
                                              AIV-204

-------
                                                                                    Tetryl

                               PRODUCTION  DATA
Annual U.S.
 Production:                                    Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                        '              duction Lost:

Release Rate (million Ibs/yr):
                                  TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
     LDSO               500 mg/kg             dog                 subcutaneous
     LDLo              5000 mg/kg             dog                 subcutaneous

Non-lethal Acute Effects:
     Dermatitis
     Conjunctivitis
     Nausea and vomiting
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 1.5 mg/m3 (skin)



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:  1.5 mg/m3 (skin)

   Other Chronic Effects:
      Anemia
      Gastrointestinal conditions
                                        AIV-205

-------
Thiuram
                                     CHEMICAL  NAME


    CAS Number:    137-26-8

    Chemical Name:     Bis(dimethyl thiocaibamoyl)disulflde
    Synonyms:   Tetramethyl thiuramdisulfide
                Disulfutam
                TTD
    Molecular
      Formula:   C6H12N2S4
                   CH,
                        CH,
    Structure:
                   CH
 \    II          II     /
  N-C-S-S-C-N

3 '
                                             CH,
    Chemical Properties

       Molecular Weight:   240.44

       Vapor Pressure:  Negligible

       Boiling Point:    129°Cat20mm

       Density:  1.30 at 20° C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
           Disaster hazard-dangerous-NOx and SOX
                                Thiouram
                              Physical State:   Solid

                              Vapor Density:

                              Melting Point:   155 to 156°C

                              Solubility:   Insoluble (H2O)
                                             AIV-206

-------
                                                                                 Thiuram
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
15.7 x 10° Ibs. (1972)
Consumption:

Fraction of Pro-
 duction Lost:   0.015
Release Rate (million Ibs/yr):
                                  TOXICITY DATA
Acute Toxicity
      LD50
              Dosage
            560 mg/kg
           1350mg/kg
            210 mg/kg
            780 mg/kg
            200 mg/kg
            230 mg/kg
 Non-lethal Acute Effects:
      Liver and.kidney injury
      Brain damage
      Irritation of eyes, nose and throat
 Animal
 lat
 mouse •'
 rabbit
 mammal
 mouse
 cat
  Route
oral
oral
oral
unknown
intraperitoneal
oral
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 5 mg/m3



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV: 5 mg/m3 (air)
      TDLo    250 mg/kg (6-17 days of pregnancy)    mouse               oral
              250 mg/kg (8 days of pregnancy)      hamster              oral
   Other Chronic Effects:
                                        AIV-207

-------
o-Tolidine
                                      CHEMICAL  NAME
     CAS Number:    119-93-7

     Chemical Name:    3,3'-Dimethylbenzidine

     Synonyms:   oTolidine
                 3,3'-Dimethyldiphenyl-4,4'-diamine
    Molecular
      Formula:
     Chemical Properties

        Molecular Weight:   212.30

        Vapor Pressure:

        Boiling Point:

        Density:

        Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

        BOO:

        Atmospheric Reactivity:
Physical State:     Solid

Vapor Density:

Melting Point:   131 to 132°C

Solubility:   Slightly (H2O)
     Safety Hazard:
                                              AIV-208

-------
                                                                             o-Tolidine

                               PRODUCTION DATA
Annual U.S.
 Production:                                    Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LD50               404 mg/kg              rat                 oral
      LDLo              • 125 mg/kg              rat                 intraperitoneal
                         125 mg/kg              mouse              intraperitoneal
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
   Recognized carcinogen
         TD             2250 mg/kg (30 days)     rat                 oral
                        2880 mg/kg (34 weeks)    rat                 subcutaneous
                        4480 mg/kg (1 year)       rat                . implant
   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
                                        AIV-209

-------
Toluene
    CAS Number:    108-88-3

    Chemical Name:    Toluene

    Synonyms:    Methyl benzene
                 Phenyl methane
                 Toluol
    Molecular
      Formula:    C7H8
    Structure:
                                      CHEMICAL  NAME
     Chemical Properties

       Molecular Weight:   92.15

       Vapor Pressure:  28.4 mm at 25°C

       Boiling Point:   110.6°C at 760 mm

       Density:   0-8669 at 20°C/4°C

      . Octanol/Water Parti-
         tion Coefficient:   2.80

     Environmental Persistence

       BOD:     86% of theoretical after 20 days at 20°C
                 Total theoretical oxygen demand = 3.13 gm/gm
       Atmospheric Reactivity:
                 Reacts with oxidizing materials
                 Unreactive to O3 and RO2 (Tw = 103 - 106 days)
                 Reactive toward OH
                 No photochemical degradation

     Safety Hazard:
           Fire—dangerous
           Explosion—moderate
           Disaster hazard-moderate-toxic fumes
Physical State:   Liquid

Vapor Density:  3.14

Melting Point:   -95°C

Solubility:   Insoluble (H2O)
                                             AIV-210

-------
                                                                                  Toluene
                                PRODUCTION DATA
Annual U.S.
 Production:   6,937.9 x 10° Ibs. (1974)

Fraction of
 Dispersion:     0.15

Release Rate (million Ibs/yr):  1074.2
                      Consumption:   5,420 x 10° Ibs. (1975)

                      Fraction of Pro-
                       duction Lost:  0.01
                                  TOXICITY DATA
Acute Toxicity
      LDSO

      LC5o
      LDLo
  Dosage                Animal
5400 mg/kg             rat
1640mg/kg             rat
5 300 ppm               mouse
 800 mg/kg             rat
5 000 mg/kg             rat
4000 ppm (4 hours)       rat
  Route
oral
inttaperitoneal
inhalation
intra peritoneal
subcutaneous
inhalation
Non-lethal Acute Effects:
      Central nervous system
        TCLo              200 ppm
      Psycho trophic
        TCLo              100 ppm
                        human
inhalation

inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) NIOSH Recommended Standard:
      TWA     200 ppm
      Ceiling   300 ppm
      Peak concentration  500 ppm/10 minutes
   Carcinogenicity:
      (Suspected) 100% solution                    mouse
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
      Blood abnormalties
      Bone marrow chromosome damage
      Metabolic effects
      Enzymatic effects
      Increased liver microsomal enzymes
                                          dermal
                      TLV:
                      Odor perception: 40 ppm
                                        AIV-211

-------
Toiiiene-2, 4-diamine
                                     CHEMICAL NAME
    CAS Number:    95-80-7

    Chemical Name:     Toluene-2, 4-diamine

    Synonyms:   Tolylene diamine
                2,4-Diaminotoluene
    Molecular
      Formula:
                           NH,
    Structure:
                              CH,
     Chemical Properties

       Molecular Weight:   122.17

       Vapor Pressure:  1 mm at 106.5°C

       Boiling Point:    292°C

       Density:

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
           Disaster hazard-moderate-toxic fumes
Physical State:  Solid

Vapor Density:

Melting Point:   99°C

Solubility:    Very soluble (hot H2O)
                                           .AIV-212

-------
                                                            Toluene-2, 4-diamine
                              PRODUCTION DATA

Annual U.S.
 Production:    63 x 106 Ibs.                      Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage              Animal               Route
      LDLo               500 mg/kg             rat                 oral
                          50 mg/kg             rat                 unreported
                         200 mg/kg             dog                subcutaneous
                         350 mg/kg             dog                unreported
                         400 mg/kg             rabbit              unreported
                         200 mg/kg             guinea pig           unreported

 Non-lethal Acute Effects:
      Liver damage
      Skin irritation
      Anemia
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      Neoplasm:
        TDLo            280 mg/kg (35 weeks)    rat                 subcutaneous
   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects;
                                       AIV-213

-------
Toluene diisocyanate
                                     CHEMICAL NAME


    CAS Number:    91-08-7

    Chemical Name:    Isocyanic acid, 2-methyl-m-phenylene ester

    Synonyms:   Isocyanic acid, methyl phenylene estei
                TDI
                2,4-Toluene diisocyanate
    Molecular
      Formula:   C9H6N2O2



                               N = C = O

    Structure:    O = C = N-^-  \- CH3
    Chemical Properties

       Molecular Weight:   174.16                     Physical State:  Liquid

       Vapor Pressure: <0.01 mm at 20°C              Vapor Density:  6.0

       Boiling Point:   238.3°C                       Melting Point:   19.5to21.5°C

       Density:  1.22 at 20°C/4°C                     Solubility:   Reacts with H2O producing CO2

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
           Reacts slowly with 63 and RO2
           TVJ, OH = 3 days
           Hydrolyzes in H2O(pH 7.0) t^ = 0.5 seconds


    Safety  Hazard:
           Disaster hazard-dangerous-toxic fumes
                                            AIV-214

-------
                                                             Toluene diisocyanate
Annual U.S.
 Production:   420 x 106 Ibs.

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):   6.3
                               PRODUCTION DATA
                                              Consumption:
                                               Fraction of Pro-
                                                duction Lost:   0.015
                                 TOXICITY DATA
Acute Toxicity
      LCSO
                         14 ppm (4 hours)
                         10 ppm (4 hours)
                         13 ppm (4 houts)
Animal
rat
mouse
guinea pig
 Non-lethal Acute Effects:
      Irritant
         TCLo             0.5 ppm              human
    •  Pulmonary edema
      Allergies produced severe dermatitis and bronchial spasms
  Route
inhalation
inhalation
inhalation
                                                                  inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) Ceiling-140 Mg/m3
                           NIOSH recommends: (air) TWA 5 ppb
   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
   Liver disease
                                              TLV: 0.02 ppm-below level of odor perception
                                       AIV-215

-------
Toluenesulfonamide
                                    CHEMICAL NAME
    CAS Number:     70-55-3

    Chemical Name:   p-Toluene sulfonylamide

    Synonyms:    p -Toluene sulfonamide
                 4-Toluenesulfonic acid, amide

    Molecular
     Formula:  C7H9NO2S
                O
                II
Structure:   H,N - S
                ii
                O
    Chemical Properties

       Molecular Weight:  171.22

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence  .

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                                CH,
                                              Physical State:    Solid

                                              Vapor Density:

                                              Melting Point:  138.5 to 139°C

                                              Solubility:  Slightly (H2O)
                                            AIV-216

-------
                                                           Toluenesulfonamide
                             PRODUCTION DATA

Annual U.S.
 Production:                                  Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITYDATA

Acute Toxicity              Dosage             Animal              Route
      LD50               75 mg/kg             wild bird           oral
                        250 mg/kg             mouse             intrapeiitoneal
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-217

-------
o-Toluenesulf onic acid
                                     CHEMICAL NAME
    CAS Number:   88-20-0

    Chemical Name:    o-Toluenesulfonic acid

    Synonyms:   o-Toluenesulfonate
                2-Toluenesulfonic acid
    Molecular
     Formula:
    Structure:  .  <     />-  CH3
                     OH
    Chemical Properties

       Molecular Weight:   172.21

       Vapor Pressure:

       Boiling Point:   128. 8° Cat 25 mm

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:     Solid

Vapor Density:

Melting Point:  67.5°C

Solubility:    Very soluble (H2O)
                                            AIV-218

-------
                                                          o-Toluenesulfonic acid
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                              PRODUCTION DATA
                   Consumption:

                   Fraction of Pro-
                    duction Lost:
Acute Toxicity
      TOXICITY DATA

Dosage               Animal
 Non-lethal Acute Effects:
      High irritant
      Moderate systemic toxicity  •
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                   TLV:
Route
                                     AIV-219

-------
p-foluenesulfonic acid
                                     CHEMICAL NAME
    CAS Number:   104-15-4

    Chemical Name:   p-Toluenesulfonic acid

    Synonyms:   p -Toluene sulfonate
    Molecular
      Formula:  C7H8O3S
    Structure:
HO-i
    Chemical Properties

       Molecular Weight:     172.21

       Vapor Pressure:

       Boiling Point:   140°Cat 20mm

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                                  Physical State:  Solid

                                  Vapor Density:

                                  Melting Point:  104 to 105°C

                                  Solubility:  Very soluble (H2O)
                                            AIV-220

-------
                                                         p-Toluenesulfonic acid
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
     LD50              400 mg/kg            rat                oral

Non-lethal Acute Effects:
     High irritant
     Moderate systemic toxicity
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-221

-------
Toluenesulfonyl chloride
                                    CHEMICAL  NAME
    CAS Number:   98-59-9

    Chemical Name:    p-Toluenesulfonyl chloride

    Synonyms:
    Molecular
     Formula:   C7H7C1O2S
                  O
                   II
    Structure:   Cl - S -\\    //
                   I,   \\   //
                  O
CH,
    Chemical Properties

       Molecular Weight:   190.65

       Vapor Pressure:

       Boiling Point:   145 to 146°C at 15 mm

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                   Physical State:     Solid

                   Vapor Density:

                   Melting Point:  71°C

                   Solubility:     Insoluble (H2O)
    Safety Hazard:
                                           AIV-222

-------
                                                     Toluenesulfonyl  chloride
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                             PRODUCTION DATA
                                            Consumption:

                                            Fraction of Pro-
                                             duction Lost:
Acute Toxicity
                                TOXICITY DATA

                          Dosage              Animal
Non-lethal Acute Effects:
     Severe irritant
     Moderate systemic toxicity
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                            TLV:
                                                                Route
                                     AIV-223

-------
m-Toluidine
                                      CHEMICAL  NAME
    CAS Number:   108-44-1

    Chemical Name:    m-Toluidine

    Synonyms:  m-Methyl aniline
                3-Aminotoluene
                3-Amino-l-methylbenzene
    Molecular
      Formula:   C7H9N
                   NH2
    Structure:      d    \-  CH3
     Chemical Properties

       Molecular Weight:  107.16                       Physical State:  Liquid

       Vapor Pressure:  1 mm at 41°C                    Vapor Density:  3.90

       Boiling Point:   200.23°C at 760 mm              Melting Point:   -14.7°C

       Density:  0.9984 at 20°C/4°C                     Solubility:   Slightly (H2O)

       Octanol/Water Parti-
         tion Coefficient:     1.60

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
          Disaster hazard-dangerous-toxic fumes
                                              AIV-224

-------
                                                                             m-Toluidine
                                PRODUCTION DATA

Annual U.S.
 Production:                                     Consumption:

Fraction of                                       Fraction of Pro-
 Dispersion:                                       duction Lost:

Release Rate (million Ibs/yr):
                                  TOXICITY DATA

Acute Toxicity                Dosage               Animal               Route
      LDSO               974 mg/kg              rat                 oral
                         150 mg/kg              mouse              intiaperitoneal

Non-lethal Acute Effects:
      Local irritant
      Allergies
      Headache
      Irritation
      Difficulty in breathing
      Psychic disturbances
      Marked irritation of the kidneys and bladder
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      Neoplasm:
        TDLo            6600 Mg/kg (19 weeks)    rat                 oral
   Mutageniciry:

   Teratogenicity:                                 TLV:

   Other Chronic Effects:
                                       AIV-225

-------
o-Toluidine
                                      CHEMICAL  NAME
    CAS Number:   95-53-4

    Chemical Name:     o-Toluidine

    Synonyms:    o-Methyl aniline
                 2-Methyl aniline
                 2-Amino toluene
    Molecular
      Formula:    C7H9N
                         NH,
    Structure:
    Chemical Properties

       Molecular Weight:   107.16

       Vapor Pressure:  1 mm at 44°C

       Boiling Point:   200.23°C at 760 mm

       Density:  0.9984 at 20°C/40C

       Octanol/Water Parti-
         tion Coefficient:   !-61
Physical State:   Liquid

Vapor Density:  3.69

Melting Point:   -23.7°C (unstable)
               -14.7°C (stable)
Solubility:   Slightly (H2O)
     Environmental Persistence

       BOD:     45% of theoretical

       Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
           Fire-moderate
           Disaster hazard-dangerous-toxic fumes
                                             AIV-226

-------
                                                                              o-Toluidine
                                PRODUCTION DATA

Annual U.S.
 Production:                                     Consumption:

Fraction of                                       Fraction of Pro-
 Dispersion:                                       duction Lost:

Release Rate (million Ibs/yr):
                                  TOXICITY DATA

Acute Toxicity                Dosage         .      Animal               Route
      LD50               900mg/kg              rat                  oral
                          150 mg/kg              mouse               intraperitoneal
                         3250 mg/kg              rabbit               skin
      LDLo               300 mg/kg              cat                  oral
                            5 mg/kg              frog                 oral

 Non-lethal Acute Effects:
      Difficulty in breathing
      Headache
      Marked irritation of kidneys and bladder
      Psychic disturbance
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 5 ppm (skin)"



   Carcinogenicity:
      Neoplasm TDLo     8200 mg/kg (24 weeks)    rat                  oral

   Mutagenicity:

   Teratogenicity:                                 TLV:   5 ppmTskin)

   Other Chronic Effects:
                                        AIV-227

-------
p-Toluidine
                                      CHEMICAL  NAME
    CAS Number:    106-49-0

    Chemical Name:     p-Toluidine

    Synonyms:   p-Methyl aniline
                4-Amino toluene

    Molecular
      Formula:   C7H9N
    Structure:    H2N -<(
    Chemical Properties

       Molecular Weight:   107.16

       Vapor Pressure:  1 mm at 42°C

       Boiling Point:    200.55°C at 760 mm

       Density:  0.9619 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:   Solid

Vapor Density:  3.90

Melting Point:   43.7°C

Solubility:   Slightly (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-moderate
          Disaster hazard-dangerous-toxic fumes
                                              AIV-228

-------
                                                                            p-Toluidine

                               PRODUCTION DATA
Annual U.S.
 Production:                                    Consumption:

Fraction of                                      Fraction of Pro-
 Dispersion:                                      duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LD50              50 mg/kg              mouse               intraperitoneal
                         42 mg/kg              wild bird             oral
      LDLo              100 mg/kg              mammal             oral

 Non-lethal Acute Effects:
      Difficulty in breathing
      Kidney damage
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:    Recognized carcinogen


   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
                                       AIV-229

-------
Toxaphene
                                     CHEMICAL  NAME
    CAS Number:   8001-35-2

    Chemical Name:    Toxaphene

    Synonyms:  Chlorinated camphene
               Stiobane
               Atttox
    Molecular
      Formula:  C10H8C18
    Structure:
    Chemical Properties

       Molecular Weight:  413.84

       Vapor Pressure:  0.2 to 0.4 mm at 25°C

       Boiling Point:   Decomposes

       Density:   1.66 at 20°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Geniphene
Physical State:     Solid

Vapor Density:

Melting Point:  65 to 90°C

Solubility:   3 ppm at 25°C (H2O)
     Safety Hazard:
          Disaster hazard-dangerous-toxic fumes-chlorides
                                             AIV-230

-------
                                                                            Toxaphene
                               PRODUCTION DATA
Annual U.S.
 Production:   48 x 106 Ibs.

Fraction of
 Dispersion:    1-0

Release Rate (million Ibs/yr):     50.5
                      Consumption:   48 x 106 Ibs.

                      Fraction of Pro-
                       duction Lost:    0.01
Acute Toxicity
      LDLo
         TOXICITY DATA

                       Animal
  60 mg/kg             rat
 780 mg/kg             rat
1025 mg/kg             rabbit
  71 mg/kg             duck
  40 mg/kg             human
2000 mg/m  (2 hours)    mouse
 180 mg/kg             mouse
  50 mg/kg             dog
 780 mg/kg             rabbit
Non-lethal Acute Effects:
      Nausea and vomiting
      Muscle cramps
      Irritation of respiratory tract
Chronic Toxicity

   U.S. Occupational Standard:  7 ppm for food residues


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                                TLV:

   Other Chronic Effects:
  Route
oral
skin
skin
oral
oral
inhalation
interperitoneal
oral
oral
                                        AIV-231

-------
Tributyl phosphate
                                    CHEMICAL NAME
    CAS Number:   126-73-8

    Chemical Name:    Phosphoric acid, tributyl ester

    Synonyms: •  Tributyl phosphate
    Molecular
      Formula:
                                   O
                                   II
    Structure:  CH3 - CH2 - CH2 - O - P - O - CH2 - CH2 - CH2 - CH3

                                   O - CH2 - CH2 - CH2 - CHj
    Chemical Properties

       Molecular Weight:  266.32                     Physical State:  Liquid

       Vapor Pressure:  20 mm at 20°C       '          Vapor Density:  9.20

       Boiling Point:   289°C                        Melting Point:

       Density:  0.9727 at 25°C/4°C                   Solubility:  Soluble (H2O)

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
          Disaster hazard-dangerous phosphates
                                           AIV-232

-------
                                                             Tributyl phosphate
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                              PRODUCTION DATA
                     Consumption:

                     Fraction of Pro-
                      duction Lost:
                                TOXICITY DATA
Acute Toxicity
     LD50
     LDLo

Non-lethal Acute Effects:
     Stimulation of CNS
3000 mg/kg
  63 mg/kg
 Animal
rat
mouse
Chronic Toxicity

   U.S. Occupational Standard:   (air) TWA 5 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                     TLV:5 ppm
  Route
oral
intra peritoneal
                                      AIV-233

-------
Trichloroaniline
                                     CHEMICAL  NAME
    CAS Number:    634-93-5

    Chemical Name:  2,4,6-Trichloioaniline

    Synonyms:   Trichloroaniline
                 sym-Trichloroaniline

    Molecular
      Formula:   C6H4C13N
                          Cl
    Structure:
Cl
                     \  /
NH,,
                           Cl
    Chemical Properties

       Molecular Weight:   196.46

       Vapor Pressure:  1 mm at 134°C

       Boiling Point:    262°C at 746 mm

       Density:

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
                                   Physical State:   Solid

                                   Vapor Density:

                                   Melting Point:   78.5°C

                                   Solubility:   Insoluble (H2O)
                                             AIV-234

-------
                                                                   Trichloroaniline
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-235

-------
Trichlorobenzene
                                     CHEMICAL  NAME
    CAS Number:    120-82-1

    Chemical Name:     1,2,4-Trichlorobenzene

    Synonyms:
    Molecular
      Formula:   C6H3a3
    Structure:
     Chemical Properties

       Molecular Weight:   181.45

       Vapor Pressure:  l mm at 40°C

       Boiling Point:    213.5°C at 760 mm

       Density:  1.4542 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:  Liquid

Vapor Density:  6.26

Melting Point:   16.95°C

Solubility:   Insoluble (H2O)
     Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
     Safety Hazard:
           Fire-slight
           Disaster hazard—dangerous toxic fumes-chlorides
                                           AIV-236

-------
                                                                  Trichlorobenzene
                               PRODUCTION DATA

Annual U.S.
 Production:   10 x 10° lbs.( 1975 estimate)          Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                      .                duction Lost:   0.015

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LD50               756 mg/kg              rat                oral
                         766 mg/kg              mouse              oral
      LDLo               500 mg/kg              mouse              intrapeiitoneal

 Non-lethal Acute Effects:
      Local irritant
      Causes loss of hair
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-237

-------
1,1, 1-Trichloroethane
                                    CHEMICAL  NAME
    CAS Number:   71-55-6

    Chemical Name:    1,1,1-Trichloroethane

    Synonyms:  a-Trichloroethane
               Methyl chloroform

    Molecular
     Formula:  C2H3Cl3
                   H  Cl
                   II
    Structure:   H - C - C - Cl
                   I    I
                   H  Cl
    Chemical Properties

       Molecular Weight:   133.41

       Vapor Pressure:  130.86 at 25°C

       Boiling Point:    74.1°C at 760 mm

       Density:   1.3390 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:      Liquid

Vapor Density:  4.55

Melting Point:   -30.41°C

Solubility:   Insoluble (H2O)
    Safety Hazard:
          Disaster hazard—dangerous-chlorides .
                                            AIV-238

-------
                                                          1,  1,  1-Trichloroethane
                               PRODUCTION DATA
Annual U.S.
 Production:   591 x 106 Ibs. (1974)

Fraction of
 Dispersion:    0.73

Release Rate (million Ibs/yr):  284.5
                     Consumption:   591 x 10° Ibs.

                     Fraction of Pro-
                      duction Lost:  0.015
Acute Toxicity
      LDSO
5660 mg/kg
9470 mg/kg
Non-lethal Acute Effects:
     Psychotiophic effects:
        TCLo             350 ppm
     CNS effects:
        TCLo             920 ppm
                                 TOXICITY DATA
Animal
rabbit
guinea pig
                      human male


                      human
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:
                     TLV:   350 ppm
   Other Chronic Effects:
      Reduced growth
      Reversible dystrophic changes in liver, kidneys, myocardium and lungs
      Narcotic effect
  Route
oral
oral
                   inhalation


                   inhalation
                                       AIV-239

-------
  , 2-Trichloroethane
                                 CHEMICAL NAME
CAS Number:   79-00-5

Chemical Name:    1,1, 2-Trichloroethane

Synonyms:   Vinyl trichloride'
            (3-Trichloroethane
Molecular
 Formula:
Structure:
    Cl  Cl
    i    r
H-C-C-H
    I    I
    H  Cl
Chemical Properties

   Molecular Weight:   133.41

   Vapor Pressure:  25 mm at 25°C

   Boiling Point:   113.77°Cat 760mm

   Density:   1.4397 at 200C/4°C

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
                                   Physical State:  Liquid

                                   Vapor Density:

                                   Melting Point:   -36.5°C

                                   Solubility:   Slightly (H2O)
Safety Hazard:
      Disaster hazard-dangerous-toxic fumes-chlorides
                                       AIV-240

-------
                                                          1,  1, 2-Trichloroethane
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                               PRODUCTION DATA
                     Consumption:

                     Fraction of Pro-
                      duction Lost:
Acute Toxicity
      LDSO

      LDLo
      LCLo

 Non-lethal Acute Effects:
      Psychotic effects:

       _JCLo_
      CNS effect's
        TOXICITY DATA

 Dosage               Animal
580 mg/kg              rat
227 mg/kg              mouse
750 mg/kg              dbg
 95 mg/kg              dog
500 mg/kg              rabbit
500 ppm (8 hours)       rat
350 ppm               man
920 ppm               human
 Route
oral
subcutaneous
oral
intravenous
subcutaneous
inhalation
inhalation
inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 10 ppm (skin)
   Carcinogenicity:
      Not carcinogenic according to Dow Chemical Co. after 12-month test
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                     TLV:
                                       AIV-241

-------
Trichloroethylene
                                      CHEMICAL  NAME
CAS Number:    79-01-6

Chemical Name:     Trichloroethylene

Synonyms:   Ethylene trichloride
            Trichloroethene
    Molecular
      Formula:
                Cl
    Structure:
                    C=C
                          Cl
                          Cl
                                                     Ethinyl trichloride
                                                     Acetylene trichloride
                                                Physical State:   Liquid

                                                Vapor Density:  4.53

                                                Melting Point:   -73°C

                                                Solubility:   Slightly (H2O)
     Chemical Properties

       Molecular Weight:   131.39

       Vapor Pressure:  77.5 mm at 25°C

       Boiling Point:    87°C at 760 mm

       Density:  1.4642 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOD:
       Atmospheric Reactivity:
           Common air contaminant
           Slowly oxidized by 03 and RO2; products are phosgene, HC1, CO, trichloroethylene oxide and
             dichloroacetylchloride
           Unreactive towards OH

     Safety Hazard:
           Fire-slight
           Disaster hazard—dangerous—toxic fumes-chlorides
                                            AIV-242

-------
                                                                    trichloroethylene
                                PRODUCTION DATA
Annual U.S.
 Production:    285.2 x 10° Ibs. (1975)

Fraction of
 Dispersion:     0-95

Release Rate (million Ibs/yr):  429.5
                                             Consumption:  370 to 390 x 10 Ibs. (1975 estimate)

                                             Fraction of Pro-
                                              duction Lost:  0.015
Acute Toxicity
      LDLo
                               TOXICITY DATA

                         Dosage               Animal
                       4920 mg/kg            rat
                         34 mg/kg            mouse
                       1900 mg/kg            dog
                        857 mg/kg            human
                       1800 mg/kg            rabbit
                       5860 mg/kg            dog
                        150 mg/kg            dog
                       3000 ppm (2 hours)      mouse
                      11,000 ppm              rabbit
                       8000 ppm (8 hours)      rat
 Non-lethal Acute Effects:
      CNS effects
         TCLo
      Conjunctivitis
      Irritation of skin and respiratory tract
                       160 ppm (8 3 minutes)    human
  Route
oral
intravenous
Lntraperitoneal
oral
subcutaneous
oral
intravenous
inhalation
inhalation
inhalation
inhalation
Chronic Toxicity
                            (air)
U.S. Occupational Standard:
   TWA    100 ppm
   Ceiling   200 ppm (recommended 150 ppm)
   Peak     300 ppm/5 minutes/2 hours
Carcinogenicity:
   TDLo                351 gm/kg (78 weeks)

Mutagenicity:

Teratogenicity:

Other Chronic Effects:
   Kidney, spleen, and liver damage
   Metabolic and enzymatic effects
   Hypertension                   .
   Decreased ATP level           •    i      •
   Reduces antibody formation
                                                mouse
                                                                    oral
                                                TLV:   100 ppm
                                        AIV-243

-------
Trichlorofluoromethane
                                    CHEMICAL  NAME
    CAS Number:    75-694

    Chemical Name:  Trichlorofluoromethane

    Synonyms:    Freon 1 1
                 Monofluorotrichloromethane
    Molecular
      Formula:
                       Cl
                       I
    Structure:      Cl - C -  F
                       I
                       Cl
    Chemical Properties

       Molecular Weight:    137.38                     Physical State:    Liquid

       Vapor Pressure:   717.5mmat25°C              Vapor Density:

       Boiling Point: 24.1°C                          Melting Point:

       Density:   1.494 at 17.2°C                      Solubility:    Slightly (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
           Disaster hazard-toxic fumes-chlorides and fluorides
                                            AIV-244

-------
                                                       Trichlorofluoromethane
                              PRODUCTION DATA

Annual U.S.
 Production:    299.6 x 10* Ibs.                  Consumption:    299.6 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:    0.90                            duction Lost:   0.015

Release Rate (million Ibs/yr):   274.l
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route


 Non-lethal Effects:
       Narcosis
       Anesthesia
       Cardiotoxic
Chronic Toxicity

   U.S. Occupational Standard:  (aii) TWA lOOOppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:   1000 ppm

   Other Chronic Effects:
                                      AIV-245

-------
Trichloroisocyanuric  acid
                                     CHEMICAL  NAME


    CAS Number:    87-90-1

    Chemical Name:  l,3,5-Trichloro-s-triazine-2,4,6(lH,3H,5H)-trione

    Synonyms:   Trichloroisocyanuric acid
                Trichlorotriozinetrione
    Molecular
      Formula:
                        Cl
                         I
    Structure:
                   n
                     r
                  CI     o     Cl
    Chemical Properties

       Molecular Weight:   232.5

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:   Solid

Vapor Density:

Melting Point:    225 to 230°C

Solubility:    Soluble (12 gm/lHjO)
    Safety Hazard:
           Disaster hazard-dangerous Cl and CO gases
                                            AIV-246

-------
                                                       Trichloroisocyanuric  acid
                               PRODUCTION DATA

Annual U.S.
 Production:     40 x 106 Ibs.                     Consumption:    40 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:  1-0                                 duction Lost:   0.03

Release Rate (million Ibs/yr):   41.2
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
       LDSO               750 mg/kg             rat                 oral

  Non-lethal Acute Effects:
       Irritant to skin and tissue
Chronic Toxicity

   U.S. Occupational Standard:
     FDA regulation for use as sanitizing agent:
        100 ppm Cl~ in aqueous solution

   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-247

-------
Trichloronaphthalene
                                    CHEMICAL  NAME
    CAS Number:     2437-54-9

    Chemical Name:   1,4,6-Trichloronaphthalene

    Synonyms:
    Molecular
     Formula:  Ci0H5Cl3
    Structure:
    Chemical Properties

       Molecular Weight:     231.51

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
         Disaster hazard-dangerous-chlorides
Physical State:

Vapor Density:

Melting Point:

Solubility:
Solid
                                           AIV-248

-------
                                                          Trichloronaphthalene
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
                             PRODUCTION DATA
                    Consumption:

                    Fraction of Pro-
                     duction Lost:
Acute Toxicity
Non-lethal Acute Effects:
      Systemic effects:
        TCLo
       TOXICITY DATA

 Dosage              Animal
30 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
human
                    TLV:
                    Route
inhalation
                                      AIV-249

-------
Trichlorophenoxyacetic  acid
                                     CHEMICAL  NAME
     CAS Number:   93-76-5

     Chemical Name:    (2,4,5-Trichlorophenoxy)acetic acid

     Synonyms:   2,4,5-Trichlorophenoxyacetic acid
                2,4,5-T

     Molecular
      Formula:   C8H5C13O3
                         Cl
     Structure:
                   Cl
O - CH9 - C - OH
          II
          O
     Chemical Properties

       Molecular Weight:     255.49

       Vapor Pressure:  Low

       Boiling Point:

       Density:   l.SOat 20°C/20°C

       Octanol/Water Parti-
         tion Coefficient:

     Environmental Persistence

       BOO:

       Atmospheric Reactivity:
     Safety Hazard:
          Disastei hazard—dangerous chlorides
                       Physical State:  Solid

                       Vapor Density:

                       Melting Point:  157 to 158°C

                       Solubility:   Insoluble (H2O)
                                            AIV-250

-------
                                                    Trichlorophenoxyacetic acid
Annual U.S.
 Production:
6.0 x 106 Ibs.
                               PRODUCTION DATA
Consumption:
Fraction of
 Dispersion:  Estimated as 1

Release Rate (million Ibs/yr):  6.0
                                Fraction of Pro-
                                  duction Lost:  0.015
                                 TOXICITY DATA
Acute Toxicity
      LD50
             Dosage
           500 mg/kg
           300 mg/kg
           500 mg/kg
           389 mg/kg
           100 mg/kg
           381 mg/kg
           310 mg/kg
           500 mg/kg
 Animal
 male lat
 rat
 rat
 mouse
 dog
 guinea pig
 chicken
 mammal
  Route
oral
oral
unieported
oral
oral
oral
oral
oral
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA 10mg/m3



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:
      TDLo               100 mg/kg        .     rat (6-15 days-pregnant)     oral
                        <150 Mg/kg              mouse (6-14 days-pregnant)  subcutaneous
               (The teratogenicity is due in part to 2,3,7,8-TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin)
               which is present as a contaminant)
   Other Chronic Effects:                          TLV:
                                        AIV-251

-------
Trichloropropane
                                     CHEMICAL NAME
    CAS Number:     96-184

    Chemical Name:   1,2,3-Trichloropropane

    Synonyms:    Glyceiol trichloiohydrin
                 Allyl trichloride trichlorohydrin

    Molecular
      Formula:    C3HSC13
                   H   H  H
                    I   I    I
    Structure:   H-C-C-C-H
                    I   I    I
                   Cl  Cl Cl
    Chemical Properties

       Molecular Weight:   147.43

       Vapor Pressure:  3.59 mm at 25°C

       Boiling Point:  156.85°C at 760 mm

       Density:   1.3889 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:   Liquid

Vapor Density:   5.0

Melting Point:   -14.7°C

Solubility:    Slightly (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
           Fire—moderate
           Disaster hazard-dangerous-toxic fumes-chlorides
                                            AIV-252

-------
                                                                  Trichloropropane
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                     duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       LD50              320mg/kg             rat                 oral
                        1770 mg/kg             rabbit              skin
       LDLo              200 mg/kg             dog                oral
       LCLo             1000 PPm (4 hours)      rat                 inhalation

 Non-lethal Acute Effects:
       Local irritant
       Lesions in liver, kidney and heart
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA SO ppm



   Carcincgenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:   50 ppm

   Other Chronic Effects:
                                      AIV-253

-------
Trichlorotrifluoroethane
                                     CHEMICAL  NAME


    CAS Number:    76-13-1

    Chemical Name:     l,l,2-Trichloro-l,2,2-trifluoroethane

    Synonyms:   Trifluorotrichloroethane
    Molecular
      Formula:
    Structure:
    Cl  Cl
     I   I
Cl-C-C-F
     I   I
    F   F
    Chemical Properties

       Molecular Weight:   187.38

       Vapor Pressure:  337.72 mm at 25°C

       Boiling Point:    47.7°C at 760 mm

       Density:     1.5635at25°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
           Stable in lower atmosphere
     Safety Hazard:
          Fire-slight
          Disaster hazard-dangerous-toxic fumes-fluorides and chlorides
                                    Physical State:   Liquid

                                    Vapor Density:  6.47

                                    Melting Point:   -36.4°C

                                    Solubility:   Insoluble (H2O)
                                            AIV-254

-------
                                                     Trichlorotrifluoroethane
Annual U.S.
 Production:

Fraction of
 Dispersion:
                             PRODUCTION DATA
                    Consumption:

                    Fraction of Pro-
                     duction Lost:
Release Rate (million Ibs/yr):  682 (1973 emissions of F-ll and F-12)
Acute Toxicity
       TOXICITY DATA

 Dosage              Animal
Chronic Toxicity

   U.S. Occupational Standard:
   Carcinogenicity:
      TCLo

   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
4500 ppm
human
                    TLV:  1000 ppm
                   Route
                                       inhalation
                                     AIV-255

-------
Tricresyl phosphate
                                      CHEMICAL  NAME
    CAS Number:     78-30-8

    Chemical Name:   Phosphoric acid, tri-o-tolyl ester

    Synonyms:    o-Tolyl phosphate
                 Tricresyl phosphate
    Molecular
     Formula:
                                     Tri-o-cresyl phosphate
                                     Tri-o^tolyl phosphate
                                     Tri-2-tolyl phosphate
C2,H2104P
    Structure:
    Chemical Properties

       Molecular Weight:   368.37

       Vapor Pressure:  0.29 mm at 200°C

       Boiling Point:  410°C

       Density:   1.1955 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:
                                    Physical State:   Liquid

                                    Vapor Density:   12.7

                                    Melting Point: 11°C

                                    Solubility:    Insoluble (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
           Fiie-slight
           Disaster hazard-dangerous POX
                                            AIV-256

-------
                                                              Tricresyl phosphate
                               PRODUCTION DATA

Annual U.S.
 Production:    50.2 x 106 Ibs.                   Consumption:    42.7 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:   1-0                                 duction Lost:   0.015

Release Rate (million Ibs/yr):   43.5
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal              Route
       LDLo              4680 mg/kg             rat                 oral
                           500 mg/kg             dog       •          oral
                           100 mg/kg             rabbit              oral

  Non-lethal Acute Effects:
       CNS effects, paralysis
       Nausea and vomiting
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA  0.1 mg/m3



   Carcinogenicity:   Negative result in 12-week rat study


   Mutagenicity:

   Teratogenicity:                               TLV:  o.l mg/m3

   Other Chronic Effects:
                                       AIV-257

-------
Tridecylbenzenesulfonic acid, sodium  salt
                                   CHEMICAL NAME


    CAS Number:    1435640-2

    Chemical Name:    p-Tridecylbenzenesulfonic acid, sodium salt

    Synonyms:
    Molecular
      Formula:
                          CH3
                           I
                         (CH2)y
    Structure:
CH3(CH,) CH -4    />-  S
   J    L x      \,   //  - (| .

                        O
     Chemical Properties

       Molecular Weight:   361.50

       Vapor Pressure:  Negligible at 2S°C

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

     Environmental Persistence

       BOD:

       Atmospheric Reactivity:
     Safety Hazard:
                                                          x+y = 10
                                 Physical State:

                                 Vapor Density:

                                 Melting Point:

                                 Solubility:
                                          AIV-258

-------
                            Tridecylbenzenesulfonic acid, sodium salt
                            PRODUCTION DATA

Annual U.S.
 Production:   149.9 x 106 Ibs.                  Consumption:   149.9 x 106 Ibs.

Fraction of                                   Fraction of Pro-
 Dispersion:    1-°                             duction Lost:  °-015

Release Rate (million Ibs/yr):  152J
                              TOXICITY DATA

Acute Toxicity              Dosage             Animal             Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                    AIV-259

-------
Triethanolamine
                                     CHEMICAL  NAME
    CAS Number:     102-71-6

    Chemical Name:   2,2',2",-Nitrilotriethanol

    Synonyms:    Triethanolamine
                 2,2',2"-Trihydroxyethylamine

    Molecular
      Formula:    C6H15NO3
    Structure:   HO - CH2 - CH2 - N - CH2 - CH2 - OH

                                CH,
                                 i  z
                                CH,
                                 i  i
                                OH
    Chemical Properties

       Molecular Weight:   149.19                     Physical State:   Solid-liquid

       Vapor Pressure:   <0.01 mm at 20°C              Vapor Density:   5.14

       Boiling Point:  277°C at 150mm                  Melting Point:    21.2°C

       Density:   1.1242 at 20°C/4°C                   Solubility:    Infinite (H2O)

       Octanol/Water Parti-
        tion Coefficient:   -1.75

    Environmental Persistence

       BOD:     66% of theoretical after 10 days at 20° Cat 10mg/l
                 Total theoretical oxygen demand = 2.04 gm/gm
                 Resistance to biodegradation

       Atmospheric Reactivity:    Reacts with oxidizing materials
    Safety Hazard:
           Fire-slight
           Disaster hazard-dangerous-NOx
                                            AIV-260

-------
                                                                  Triethanolamine
                              PRODUCTION DATA

Annual U.S.
 Production:     100.7 x 106 Ibs.                 Consumption:    85.7 x 106 Ibs.

Fraction of                                   Fraction of Pro-
 Dispersion:  0.40                               duction Lost:   0.015

Release Rate (million Ibs/yr):   35.8
                                TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       LDSo              8000mg/kg            guinea pig           oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                     AIV-261

-------
Triethylamihe
                                     CHEMICAL  NAME
    CAS Number:    121-44-8

    Chemical Name:    Trie thy lamine

    Synonyms:   N,N-Diethylethanamine
    Molecular
      Formula:   C6H,5N
    Structure:    CH3 - CH2 - N - CH2 -

                            CH2
    Chemical Properties

       Molecular Weight:  101.19                      Physical State:   Liquid

       Vapor Pressure:                                Vapor Density:  3.48

       Boiling Point:    89.3°C at 760 mm                Melting Point:   -114.7°C

       Density:  0.7275 at 20°C/4°C                    Solubility:   Soluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:  1.37

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-dangerous
                                            AIV-262

-------
                                                                        Triethylamine
                               PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
22.8 x!06lbs. (1967)
(Includes monoethylamine)
Consumption:

Fraction of Pro-
 duction Lost:  °-015
Release Rate (million Ibs/yr):
                                 TOXICITY DATA
Acute Toxicity
      LD50
      LCLo
             Dosage
           460 mg/kg
           546 mg/kg
           570 mg/kg
          1000 ppm (4 hours)
          1000 ppm (4 hours)
 Non-lethal Acute Effects:
      Liver and kidney damage
      Irritant to skin and mucous membranes
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
 rat
 mouse
 rabbit
 rat
 guinea pig
  Route
oral
oral
skin
inhalation
inhalation
                                TLV:   25 ppm
                                       AIV-263

-------
Triethylene  glycol
                                     CHEMICAL  NAME
    CAS Number:    112-27-6

    Chemical Name:     Triethylene glycol

    Synonyms:   2.2'-Ethylene dioxy diethanol glycol
                Bis (hydroxyethyl) ether
    Molecular
     Formula:
    Structure:
C6H1404
                CH, - O - CH, - CH2 - OH
                CH2 - O - CH2 - CH2 - OH
    Chemical Properties

       Molecular Weight:    150.18

       Vapor Pressure:   1 mm at 114°C

       Boiling Point:    278.3°C at 760 mm

       Density:   I.l274at 15°C/48C

       Octanol/Water Parti-
        tion Coefficient:    -2-08

    Environmental Persistence

       BOD:     85% of theoretical after 20 days at 20°C
                Total theoretical oxygen demand =1.6 gm/gm
       Atmospheric Reactivity:
                                   Physical State:   Liquid

                                   Vapor Density:

                                   Melting Point:   -5°C

                                   Solubility:   Infinite (H2O)
    Safety Hazard:
           Fire-slight
           Explosion-moderate
                                            AIV-264

-------
                                                              Triethylene glycol
                             PRODUCTION DATA

Annual U.S.
 Production:    113xl06lbs.                   Consumption:   113xl06lbs.

Fraction of                                    Fraction of Pro-
 Dispenion:  0.75                              duction lost:   0.015

Release Rate (million Ibs/yr):  70.8
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
      LD5o              9739 mg/kg       '     mouse             subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-265

-------
Triethylene glycol,  dimethyl ether
                                    CHEMICAL  NAME
    CAS Number:     112-49-2

    Chemical Name:   2,5,8,11-Tetraoxadodecane

    Synonyms:    Triethyleneglycol dimethyl ether
                 Triglyme
                 1,2-Bis(2-methoxyethoxy)ethane
    Molecular
     Formula:    C8Hi8C>4
    Structure:  CH3 - (OCH2CH2)3 - OCH3
    Chemical Properties

       Molecular Weight:    178.22

       Vapor Pressure:    0.9 mm at 20°C

       Boiling Point:     216°C

       Density:    °-9862 at 20°C/20°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                    Physical State:   Liquid

                    Vapor Density:

                    Melting Point:   -46°C

                    Solubility:     Soluble (H2O)
Reacts with oxidizing materials
    Safety Hazard:
            Fire-slight
                                           AIV-266

-------
                                       Triethylene glycol, dimethyl  ether
                             PRODUCTION DATA

Annual U.S.
 Production:                                 Consumption:

Fraction of                                   Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal              Route
       (Low toxicity)
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogen icity:


   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                    AIV-267

-------
Triethylene glycol, monomethyl ether
                                   CHEMICAL NAME


    CAS Number:   112-35-6

    Chemical Name:    2-[2-(2-Methoxyethoxy)ethoxy]ethanol
    Synonyms:
    Molecular
     Formula:
Triethylene glycol, monomethyl ether
Methoxytriglycol
Methoxytriethylene glycol
    Structure:  CH3 - (OCH2CH2)3 - OH
    Chemical Properties

       Molecular Weight:  164.20

       Vapor Pressure: <0.01 mm at 20°C

       Boiling Point:   249°C

       Density:     1.0494

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
            Fire-slight
                                Physical State:

                                Vapor Density:

                                Melting Point:

                                Solubility:   Infinite (H2O)
                                          AIV-268

-------
                                  Triethylene glycol, monomethyl ether
                            PRODUCTION DATA

Annual U.S.
 Production:   31.7 x 106 Ibs.                   Consumption:    26.7 x 106 Ibs.

Fraction of     1.0                           Fraction of Pro-   0.015
 Dispersion:                                   duction Lost:

Release Rate (million Ibs/yr): 27.2
                              TOXICITY DATA

Acute Toxicity             Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                             TLV:

   Other Chronic Effects:
                                    AIV-269

-------
Trifluralin


                                      CHEMICAL NAME


    CAS Number:  1582-09-8

    Chemical Name:   a,a,a,-TTifluoro-2,6-dinitro-N, N-dipropyl-p-toluidine

    Synonyms:   Trifluralin
    Molecular
      Formula:
                    F        ,N<>2
                    I
    Structure:   F - C


                         ^N02  ^ "W^
    Chemical Properties

       Molecular Weight:  335.32                       Physical State:     Solid

       Vapor Pressure:   1.99 x 10"4mmat29.5°C        Vapor Density:

       Boiling Point:   139 to 140°Cat4.2 mm           Melting Point:  48.5to49°C

       Density:                                       Solubility:  Insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
             Degraded by ultraviolet irradiation
    Safety Hazard:
          Disaster hazard-dangerous nitrates and fluorides
                                             AIV-270

-------
                                                                            Trifluralin
                               PRODUCTION DATA

Annual U.S.
 Production:   20 x 106 Ibs.                      Consumption:   20 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:    1.0                                duction Lost:  0.01

Release Rate (million Ibs/yr):  20.2
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LDSO               >10,000 mg/kg         rat                 oral
                               5 gm/kg         mouse              oral
                           5000gm/kg         mouse              oral
                            500 mg/kg         rat                 oral
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                       AIV-271

-------
Triisobutylene
                                     CHEMICAL  NAME
CAS Number:     9003-274

Chemical Name:   2-Methyl-l-propene, homopolymer

Synonyms:    Triisobutylene
             2-Methylpropene (trimer)
             Poly(2-methylpropene)
Molecular
     Formula:
                  C12H24
    Structure:   (mixture of isomers)
    Chemical Properties

       Molecular Weight:   168.33

       Vapor Pressure:   2.08 mm at 25°C

       Boiling Point:  179 to 181°C

       Density: .  0.7590 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
    Safety Hazard:
                                                     Polyisobutylene
                                                Physical State:   Liquid

                                                Vapor Density:

                                                Melting Point:   -76°C

                                                Solubility:   Insoluble (H2O)
                                            AIV-272

-------
                                                                    Triisobutylene
                              PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITYDATA

Acute Toxicity              Dosage              Animal              Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                      AIV-273

-------
Trimethylamine
                                    CHEMICAL  NAME
    CAS Number:   75-50-3

    Chemical Name:    Trimethylamine

    Synonyms:  N,N-Dimethylmethanamine


    Molecular
     Formula:  C3H9N
                     CH3
                      I
    Structure:   CH3 - N - CH3
    Chemical Properties

       Molecular Weight:   59.11                       Physical State:   Gas

       Vapor Pressure:  687 mm at 0°C                  Vapor Density:  2.0

       Boiling Point:    2.87°C at 760 mm               Melting Point:   -117.2°C

       Density:  0.6356 at 20°C/4°C                    Solubility:   Very(H2O)

       Octanol/Water Parti-
        tion Coefficient:   1.45

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire—moderate
          Explosion-moderate
          Disaster hazard-moderate-toxic fumes
                                           AIV-274

-------
                                                                      Trim ethy la mine
                                PRODUCTION DATA
Annual U.S.
 Production:    28.8 x 106 Ibs.

Fraction of
 Dispersion:     °-70

Release Rate (million Ibs/yr):  20.6
                                               Consumption:   28.8 x 106 Ibs.

                                               Fraction of Pro-
                                                 duction Lost:  0.015
                                  TOXICITY DATA
Acute Toxicity               Dosage
      LDSO                90 mg/kg
      LDLo                75 mg/kg
                         1000 mg/kg
                          800 mg/kg
                          400 mg/kg
                         2000 mg/kg

 Non-lethal Acute Effects:
      Irritant to skin, respiratory organs
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                                Animal
                                                mouse
                                                mouse
                                                mouse
                                                rabbit
                                                rabbit
                                                frog
                                               TLV:
  Route
intravenous
intraperitoneal
subcutaneous
subcutaneous
intravenous
subcutaneous
                                        AIV-275

-------
Trimethylpentanediol
                                    CHEMICAL NAME
    CAS Number:   144-19-4

    Chemical Name:   2,2,4-Trimethyl-l,3-pentanediol

    Synonyms:  TMFD
    Molecular
     Formula:   C8H18O2
                     CH,
                               CH,
    Structure:   CH, - CH - CH - C - CH9OH
                           II
                          OH  CH,
    Chemical Properties

       Molecular Weight:  146.23

       Vapor Pressure:

       Boiling Point:   234°C at 737 mm

       Density:    0.937 at 15°C/1S°C

       Octanol/Water Parti-
        tion Coefficient:
Physical State:  Solid

Vapor Density:

Melting Point:  51.8to52.2°C

Solubility:   Slightly (H2O)
    Environmental Persistence

       BOD:

       Atmospheric Reactivity:  Reacts wi* oxidizing materials
    Safety Hazard:
          Fire-slight
                                          AIV-276

-------
                                                         Trimethylpentanediol
                             PRODUCTION DATA

Annual U.S.
 Production:   20 x 106 Ibs.                    Consumption:  20 x 106 Ibs.

Fraction of                                   Fraction of Pro-
 Dispersion:    °-8                              duction Lost: 0.015

Release Rate (million Ibs/yr): 16-3
                               TOXICITY DATA

Acute Toxicity              Dosage              Animal             Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                    AIV-277

-------
Trinitrotoluene
                                     CHEMICAL NAME
    CAS Number:    118-96-7

    Chemical Name:     2,4,6-Trinitiotoluene

    Synonyms:   Trinitrotoluene
               JTNT
                sym-Trinitrotoluene
    Molecular
      Formula:
    Structure:   O2N
                             NO,
/ACH3
                             NO
    Chemical Properties

       Molecular Weight:   227.13

       Vapor Pressure:

       Boiling Point:    290 to 3 10°C (explodes)

       Density:  1.654

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
                          Triton
                          s-Trinitrotoluene
                         Physical State:   Solid

                         Vapor Density:

                         Melting Point:   104°C

                         Solubility:   Insoluble (H2O)
    Safety Hazard:
          Explosion-moderate
          Disaster hazard-highly dangerous-toxic fumes
                                            AIV-278

-------
                                       Trinitrotoluene
Annual U.S.
 Production:

Fraction of
 Dispersion:

Release Rate (million Ibs/yr):
PRODUCTION DATA
               Consumption:

               Fraction of Pro-
                 duction Lost:
  TOXICITY DATA
Acute Toxicity
   Dosage
 700mg/kg
1850mg/kg
 200 mg/kg
 500mg/kg
 500 mg/kg
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                               Animal
                                              rat
                                              cat
                                              cat
                                              rabbit
                                              rabbit
                                    Route
                                   oral
                                   oral
                                   subcutaneous
                                   oral
                                   subcutaneous
               TLV:
        AIV-279

-------
Trithion
                                      CHEMICAL NAME


    CAS Number:   786-19-6

    Chemical Name: .   Phbsphoiodithioic acid, S-[ [(p-Chlorophenyl)thio] methyl] O, O-diethyl ester

    Synonyms:  Trithion
                O.O-diethyl-S-p-chlorophenylthiomethyl phosphorodithioate
                Caibophenothion
    Molecular
      Formula:  CuHi6ao2PS3
Structure:    CH3CH2O - P - s - CH2S

                       OCH2CH3



Chemical Properties

   Molecular Weight:  260.39

   Vapor Pressure:  Negligible

   Boiling Point:    82°at 0.01 mm

   Density:  1.280 to 1.285 at 20°C/20°C

   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:
                                                     Physical State:

                                                     Vapor Density:

                                                     Melting Point:

                                                     Solubility:   Insoluble (H2O)
    Safety Hazard:
          Disaster hazard-dangerous phosphates and chlorides
                                             AIV-280

-------
                                                                                  Trithion
Annual U.S.
 Production:

Fraction of
 Dispersion:
                                PRODUCTION DATA
2.0 x 106  Ibs.                      Consumption:

                                 Fraction of Pro-
                                   duction Lost:
              Estimated as 1.0

Release Rate (million Ibs/yr):    2.0
0.015
Acute Toxicity
      LDSO
             Dosage
           32 mg/kg
           10 mg/kg
           27 mg/kg
           11 mg/kg
         . 218 mg/kg
           27 mg/kg
         1270 mg/kg
           57 mg/kg
            6 mg/kg
                                  TOXICITY DATA

                                                Animal
                                                male rat
                                                tat
                                                rat
                                                rat
                                                mouse
                                                mouse
                                                rabbit
                                                chicken
                                                wild bird
     Route
   oral
   oral
   skin
   intraperitoneal
   oral
   intraperitoneal
   skin
   oral
   oral
Non-lethal Acute Effects:
      Pulmonary edema
      Convulsions
Chronic Toxicity

   U.S. Occupational Standard:  EPA farm worker reentry standard



   Carcinoganicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                 TLV:
                                       AIV-281

-------
Urea
    CAS Number:

    Chemical Name:
57-13-6


Urea
    Synonyms:  Carbamide
               Carbonyldiamine


    Molecular
     Formula:  CH4N2O
                      O
    Structure:    H2N - C - NH2
                                     CHEMICAL NAME
    Chemical Properties

       Molecular Weight:      60.06

       Vapor Pressure:

       Boiling Point:   (Decomposes)

       Density:  1.3230at20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:   -2.96

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
                               Physical State:     Solid

                               Vapor Density:

                               Melting Point:   13S°C

                               Solubility:   Very soluble (H2O)
    Safety Hazard:
                                           AIV-282

-------
^^__	      .	Urea


                                PRODUCTION DATA

 Annual U.S.   	
  Production:   8,390 x 106 Ibs. (1975)              Consumption: 8,420 x 106 Ib.s (1975)

 Fraction of                                     Fraction of Pro-
  Dispersion:                                      duction Lost:    0.15

 Release Rate (million Ibs/yr):
                                  TOXICITY DATA

 Acute Toxicity               Dosage               Animal               Route
       I.DLO              3000 mg/kg            dog                subcutaneous
                          3000 mg/kg            dog                intravenous
                          3000. mg/kg            rabbit              subcutaneous
                           600 mg/kg            frog                subcutaneous
                           511 mg/kg            domestic            oral
 Chronic Toxicity

    U.S. Occupational Standard:



    Carcinogenicity:


    Mutagenicity:

    Teratogenicity:                               TLV:

    Other Chronic Effects:
                                        AIV-283

-------
Vernam
                                    CHEMICAL  NAME
    CAS Number:    1929-77-7

    Chemical Name:     Dipiopylcarbamothioic acid, S-propyl ester

    Synonyms:   S-Propyldipropylthiocarbamate
    Molecular
     Formula:   Ci0H21NOS
                                 O       CH2CH2CH3
    Structure:     CH3CH2CH2 - S - C - N
                                         CH2CH2'CH o
    Chemical Properties

       Molecular Weight:   203.38

       Vapor Pressure:   10.4 x 10"3 mm at 25°C

       Boiling Point: 150°Cat 30 mm
       Density:  0.95 at 20°C/20°C
       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:   Liquid

Vapor Density:

Melting Point:

Solubility:   90 ppm H2O at 20°C
                                           AIV-284

-------
                                                                               Vernam
Annual U.S.
 Production:

Fraction of
 Dispersion:
               2.0 x 10" Ibs.
              Estimated as 1.0

Release Rate (million Ibs/yr):  2-°
                              PRODUCTION DATA
Consumption:

Fraction of Pro-
 duction Lost:
Acute Toxicity
       LD50
                                TOXICITY DATA
                         1800mg/kg
                         1470 mg/kg
                         1780 mg/kg
 Animal
 iat
 rat
 rat
 Route
oral
oral
urtrepoited
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                                             TLV:
                                      AIV-285

-------
Vinyl acetate
                                      CHEMICAL  NAME
    CAS Number:  108-05-4

    Chemical Name:   Vinyl acetate

    Synonyms:     Acetic acid, vinyl ester
                  Acetic acid, ethenyl estei

    Molecular
      Formula:  C4H6O2
                       O
    Structure:    CH3 - C - O - CH = CH2
    Chemical Properties

       Molecular Weight:    86.09

       Vapor Pressure:    107.5 mm at 25°C

       Boiling Point:  72.2 to 72.3°C at 760 mm

       Density:    0.9317 at 20°C/4°C

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence
Physical State:  .  Liquid (polymerizes)

Vapor Density:   3.0

Melting Point: -93.2°C

Solubility: Insoluble (H2O)
          Soluble in hot H2O
       BOD:   72% of theoretical after 20 days at 20 C
               Total theoretical oxygen demand = 1.67 gm/gm
       Atmospheric Reactivity:     Reacts with oxidizing materials
    Safety Hazard:
         Fire—highly dangerous
                                             AIV-286

-------
                                                                          Vinyl acetate
                                PRODUCTION DATA

 Annual U.S.
  Production:   1210.7 x 106 Ibs.                    Consumption:    989.4 x 106 Ibs.

 Fraction of                                      Fraction of Pro-
  Dispersion:   0                                  duction Lost:   0.015

 Release Rate (million Ibs/yr):    18.2
                                  TOXICITY DATA

 Acute Toxicity               Dosage               Animal               Route
     LDSO                 2920 mg/kg         rat                 oral
                           2320 mg/kg         rabbit               skin
     LDj_,0                  500 mg/kg         rat                 intraperitoneal
     LCL0                 4000 ppm (4 Hours)   rat            .     inhalation

Non-lethal Acute Effects:
     Skin irritant
     Vapors may be narcotic
 Chronic Toxicity

    U.S. Occupational Standard:  (air)  TWA 10 ppm



    Carcinogenicity:


    Mutagenicity:

    Teratogenicity:                                TLV:   TWA 10 ppm
     '    _     _           .                    Odor perception: 0.12 ppm
    Other Chronic Effects:
                                         AIV-287

-------
Vinyl chloride
                                     CHEMICAL NAME
    CAS Number:   75-014

    Chemical Name:   Chloroethylene

    Synonyms:     Vinyl chloride
                  Chloroethene

    Molecular
      Formula:  C2H3C1
    Structure:    CH2 = C
                          H
                          Cl
    Chemical Properties

       Molecular Weight:    62.50

       Vapor Pressure:    2660 mm at 25°C

       Boiling Point:   -13.4°C>at760mm

       Density:    0.9195 at 15°C/4°C

       Octanol/Water Parti-
         tion Coefficient:
Physical State:    Liquid or gas

Vapor Density:    2.15

Melting Point:    -153.8°C

Solubility: Slightly (1.1 gm/lH2O)
    Environmental Persistence

       BOD:   Total theoretical oxygen demand = 1.28 gm/gm

       Atmospheric Reactivity:  Reacts with oxidizing materials
         Activity toward 03:   t^ = <3 days
                       ROj:  t^ = 10s days; slow oxidation in water
                       OH:   tw = 3 days
    Safety Hazard:
          Fire—dangerous
          Explosion-severe
          Disaster hazard-very dangerous-toxic fumes
                                            AIV-288

-------
                                                                         Vinyl  chloride
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
        5088.5 x 106 Ibs.
        (4,174.6 x!06lbs., 1975)

        0.01
                        Consumption:  4467.6 x 106 Ibs.
                        Fraction of Pro-
                         duction Lost:
                                                          0.02
Release Rate (million Ibs/yr): 146.5
Acute Toxicity
     LC
Non-lethal Acute Effects:
     Cardiovascular
           TOXICITY DATA

    Dosage               Animal
100,000 to 400,000 ppm    mouse
                        dog
                        cat
                        guinea pig
Paralysis
   TCLo
Skin irritation
Conjunctivitis
                            20 ppm

                           300 ppm
                       human

                       human
                                                                Route
                                                             unknown
                                                             unknown
                                                             unknown
                                                             unknown
inhalation

inhalation
Chronic Toxicity

   U.S. Occupational Standard:  (air)  TWA    1 ppm
                                 Ceiling   5 ppm
   Carcinogenicity:
     LCLo

   Mutagenicity:
     Positive: Ames Salmonella
   Teratogenicity:
   Other Chronic Effects:
     Liver and kidney damage
     Cardiovascular damage
     Thyroid and brain degeneration
                      250 ppm (4 hours/
                      260 days)
                       rat
                                           inhalation
                                          T LV:    500 ppm or 1300 mg/m3
                                        AIV-289

-------
Vinylidene chloride
                                     CHEMICAL  NAME
    CAS Number:   75-354

    Chemical Name:    1,1-Dichloroethylene

    Synonyms:     Vinylidene chloride
    Molecular
      Formula:  C2H2C12
                 H           Cl
                    x       /
    Structure:          C = C
                    /       \
                 H           Cl
    Chemical Properties

       Molecular Weight:    97.0                      Physical State:    Volatile liquid

       Vapor Pressure:   617.14 mm at 25°C             Vapor Density:

       Boiling Point:  37°Cat760mm                  Melting Point:    -122.53°C

       Density:  1.213 at 20°C/4°C                     Solubility: Insoluble (H2O)

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:  Reacts with oxidizing materials
         Activity, towards 63:   t^ < 1 day
        I               RO2: tvi = 103 days
                       OH:  tvi
-------
                                                                Vinylidene chloride
                               PRODUCTION DATA
Annual U.S.
 Production:  260 x 106 Ibs.

Fraction of
 Dispersion:   0

Release Rate (million Ibs/yr):    2.4
                     Consumption: 54 x 106 Ibs.

                     Fraction of Pro-
                       duction Lost:    0.03
                                 TOXICITY DATA
Acute Toxicity
     LDLd
  Dosage
  3700 mg/kg
  5750 mg/kg
  225 mg/kg
10,000 ppm
Non-lethal Acute Effects:
     Irritant to eyes, skin, and respiratory tract
     Narcosis
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:   Suspected


   Mutagenicity:  Positive:  Ames bacterial system

   Teratogenicity:

   Other Chronic Effects:
 Animal
rabbit
dog
dog
rat
   Route
subcutaneous
oral
intravenous
inhalation
                     TLV:  25 ppm (suggested)
                     Odor perception:  1000 ppm
                                        AIV-291

-------
Vinyltoluene
                                     CHEMICAL  NAME
    CAS Number:      622-97-9

    Chemical Name:    p-Methylstyrene

    Synonyms:  Vinyltoluene
    Molecular
      Formula:  C9H10
    Structure:   CH2 = CH
                                CH,
                                                    Physical State:  Liquid

                                                    Vapor Density:  4.08

                                                    Melting Point:

                                                    Solubility:   Insoluble (H2O)
Chemical Properties

   Molecular Weight:   118.2

   Vapor Pressure:  1.15 mm at 20°C

   Boiling Point:   170tol71°C

   Density:  Monomer:  0.89 at 25°C/25°C
           Polymer:    1.027 at 25°C/25°C
   Octanol/Water Parti-
    tion Coefficient:

Environmental Persistence

   BOD:

   Atmospheric Reactivity:   Reacts with oxidizing material forming formaldehyde and methylbenzaldehyde
     Activity toward RC>2:  tvi = 24 hours
                   O3:   tw = 24 hours
                   OH:   tw = 1 day
    Safety Hazard:
          Fire-moderate
                                            AIV-292

-------
                                                                          Vinyltoluene
                               PRODUCTION DATA

Annual U.S.
 Production:   40 x 10 Ibs.                      Consumption:  40 x 106 Ibs.

Fraction of                                     Fraction of Pro-
 Dispersion:    O-30                               duction Lost:     0-015

Release Rate (million Ibs/yr):     12.6
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
      LDSO               4000mg/kg            rat                 oral

Non-lethal Acute Effects:
      Irritation
        TCLO             400 ppm             human             inhalation
      Damaged kidneys and liver
      Irritant to eye, nose and throat
Chronic Toxicity

   U.S. Occupational Standard:  (air) Ceiling  100 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:   1000 ppm

   Other Chronic Effects:
                                        AIV-293

-------
Warfarin


                                     CHEMICAL NAME


    CAS Number:   81-81-2

    Chemical Name:    3-(a-Acetonylbenzyl)-4-hydroxycoumarin)

    Synonyms:  Warfarin
               WARF-42
               Compound 42
    Molecular
     Formula:  C19H16O4
    Structure:
    Chemical Properties

       Molecular Weight:     308.35

       Vapor Pressure:

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:

       Atmospheric Reactivity:
Physical State:    Solid

Vapor Density:

Melting Point:    161°c

Solubility:   Insoluble (H2O)
    Safety Hazard:
                                            AIV-294

-------
                                                                                 Warfarin
Annual U.S.
 Production:

Fraction of
 Dispersion:
              12.0 x 10" Ibs.
                                PRODUCTION DATA
Consumption:
              Estimated as 1.0

Release Rate (million Ibs/yr):  13.0
Fraction of Pro-	
 duction Lost:   0.015
                                  TOXICITY DATA
Acute Toxicity
      LD50
                            Dosage
                       58 to 323 mg/kg
                              3 mg/kg
                            186 mg/kg
                            165 mg/kg
                            200 mg/kg
                            200 mg/kg
                            800 mg/kg
                            100 mg/kg
                            182 mg/kg
                            420 mg/kg
Non-lethal Acute Effects:
      Inhibition of prothromben formation
      Capillary damage
Chronic Toxicity

   U.S. Occupational Standard:


   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
 Animal
rat
rat
rat
mouse
dog
dog
rabbit
rabbit
guinea pig
rat
  Route
oral
oral
intravenous
intravenous
oral
intravenous
oral
intravenous
oral
intrapertioneal
                                                TLV:   0.1 mg/m3
                                         AIV-295

-------
m-Xylene
    CAS Number:   108-38-3

    Chemical Name:    m-Xylene

    Synonyms:     m-Xylol
    Molecular
      Formula:  C8H10
                                     CHEMICAL  NAME
    Structure:
                          CH,
Chemical Properties

   Molecular Weight:  106.2

   Vapor Pressure:    8.56 mm at 25°C

   Boiling Point:   139°C at 760 mm

   Density:     0.864 at 20°C/4°C

   Octanol/Water Parti-
    tion Coefficient:     3.20

Environmental Persistence

   BOD:    Total theoretical oxygen demand =3.17 gm/gm

   Atmospheric Reactivity:  Reacts with oxidizing materials
     Activity toward 03:   t^ = 100 years
                   RO2:  tw = 2200 years
                   OH:   t\4 = 3 days
                                                    Physical State:    Liquid

                                                    Vapor Density:    3.66

                                                    Melting Point: -47.4°C

                                                    Solubility:   Insoluble (0.13 gm/lH2O)
          Common air contaminant, reported at 0.016 to 0.61 ppm


    Safety Hazard:
          Fire-dangerous
          Explosion-moderate
                                            AIV-296

-------
                                                                                m-Xylene
                                PRODUCTION DATA
Annual U.S.
 Production:

Fraction of
 Dispersion:
               ca. 1710 x 10° Ibs. (1975)
Consumption:    ca. 1710 x 106 Ibs.
               (4907.1 x 10  Ibs.-mixed xylenes, 1975)
               (0.13-mixedxylenes)

Release Rats (million Ibs/yr):  (ca. 765-mixed xylenes)
Fraction of Pro-
 duction Lost:   0.01
               (4907 x 10° Ibs.-mixed xylenes)
Acute Toxicity
      LDSO
      LDLo

      LCLo,
                                  TOXICITY DATA

                           Dosage               Animal
                          5 000 mg/kg             rat
                          2000 mg/kg             rat
                          5000 mg/kg             rat
                          8000 ppm (4 hours)      rat
                      Route
                    oral
                    intraperitoneal
                    subcutaneous
                    inhalation
Chronic Toxicity

   U.S. Occupational Standard:   NIOSH recommended TWA 100 ppm



   Carcinogenicity:  Neoplastic effects in mice after dermal application
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
      Anorexia
      CNS disturbances
      Hyperglycemia
      Leucopenia
      Leucocytosis
      Epidermal hypertrophy.
                                               TLV:   100 ppm
                                        AIV-297

-------
o-Xylene
    CAS Number:    95-47-6

    Chemical Name:     o-Xylene

    Synonyms:   o-Xylol
    Molecular
     Formula:    C8H10
                                     CHEMICAL  NAME
    Structure:
                   CH,
                         CH,
    Chemical Properties

       Molecular Weight:   106.2

       Vapor Pressure:   10 mm at 32.1°C

       Boiling Point:    144.4°C at 760 mm

       Density:   0.880 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:  2.77
Physical State:   Liquid

Vapor Density:

Melting Point:   -25°C

Solubility:   Insoluble (H2O)
    Environmental Persistence

       BOD:     Total theoretical oxygen demand = 3 J7 gm/gm

       Atmospheric Reactivity:   Reacts with oxidizing materials
    Safety Hazard:
          Fire-moderate
          Explosion-slight
                                            AIV-298

-------
                                                                                o-Xylene


                               PRODUCTION DATA

Annual U.S.
 Production:    679.7 x 10* Ibs. (1975)             Consumption:   679.7 x 106 Ibs.

Fraction of                                      Fraction of Pro-
 Dispersion:   (0.13-mixed xylenes)                   duction Lost:   0.01

Release Rate (million Ibs/yr):   (ca. 765-mixed xylenes)



                                  TOXICITY DATA

Acute Toxicity               Dosage               Animal               Route
       LDLo               5000mg/kg            rat                 oral
                          1500mg/kg.            rat                 intra peritoneal
                          2500mg/kg            mouse              subcutaneous
                          6920 ppm              mouse              inhalation
Chronic Toxicity

   U.S. Occupational Standard:   NIOSH recommended: (aii) TWA 100 ppm



   Carcinogenicity: Neoplastic effects in mice after dermal applications


   Mutagenicity:

   Teratogenicity:                                TLV:  100 ppm

   Other Chronic Effects:
       Leucopenia and leucocytosis
       CNS disturbances
       Anorexia
       Hyperglycemia
       Epidermal hypertrophy
                                         AIV-299

-------
p-Xylene
    CAS Number:    106-42-3

    Chemical Name:     p-Xylene

    Synonyms:   p-Xylol
    Molecular
     Formula:   C8H10
                                     CHEMICAL NAME
    Structure:
    Chemical Properties

       Molecular Weight:   106.2

       Vapor Pressure:  10 mm at 27.3°C

       Boiling Point:    138.5°C at 760mm

       Density:  0-8611 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:      3.15
Physical State:     Liquid

Vapor Density:  3.66

Melting Point:   13.2°C

Solubility:   Insoluble (H2O)
    Environmental Persistence

       BOD:    Total theoretical oxygen demand = 3.179 gm/gm

       Atmospheric Reactivity:   Reacts with oxidizing materials
           Activity toward RO2:  t^ = 2200 years
                        P3:   **= 100 years
                        OH:   t% = 3 days

    Safety Hazard:
           Fire-moderate .
           Explosion-moderate
                                             AIV-300

-------
                                                                              p-Xylene
                               PRODUCTION DATA
Annual U.S.
 Production:    2419.3 x 106 Ibs. (1975)
Fraction of
 Dispersion:
0.01
Release Rate (million Ibs/yr):  39.9
Consumption:   2419.3 x 106 Ibs.

Fraction of Pro-
 duction Lost:  0.01
Acute Toxicity
      LDSO
      LDLo

      LCLo
                                 TOXICITY DATA
           5000 mg/kg
           2000 mg/kg
           5000 mg/kg
           3460 ppm
 Animal
 tat
 rat
 tat
 mouse
 Route
oral
intraperitoneal
subcutaneous
inhalation
Chronic Toxicity

   U.S. Occupational Standard:   NIOSH recommended: TWA 100 ppm



   Carcinogenicity:
   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
      Leucopenia and leucocytosis
      CNS disturbances
      Anorexia
      Hyperglycemia
      Epidermal hypertrophy
                                TLV:   100ppm
                                        AIV-301

-------
Xylenesulfonic  acid,  sodium  salt
                                    CHEMICAL NAME
    CAS Number:   827-93-0

    Chemical Name:    3,4-Xylenesulfonic acid, sodium salt

    Synonyms:  Sodium xylene sulfonate
    Molecular
     Formula:   C8H10O3S-Na
    Structure:
                     SO,<->Na<+>
                          CH3
                     CH,
    Chemical Properties

       Molecular Weight:  209.23

       Vapor Pressure:  Negligible at 25°C

       Boiling Point:

       Density:

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
Physical State:

Vapor Density:

Melting Point:

Solubility:
                                           AIV-302

-------
                                           Xylenesulfonic acid, sodium  salt
                             PRODUCTION DATA

Annual U.S.
 Production:    37.4 x 106 Ibs.                   Consumption:   37.4 x 106 Ibs.

Fraction of                                    Fraction of Pro-
 Dispersion:  1-0                                duction Lost:  0.3

Release Rate (million Ibs/yr):   38.5
                                TOXICITY DATA

Acute Toxicity               Dosage              Animal              Route
      LDSo      .       500 mg/kg             mouse             intraperitoneal
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                              TLV:

   Other Chronic Effects:
                                     AIV-303

-------
2, 6-Xylenol
                                    CHEMICAL  NAME
    CAS Number:    576-26-1

    Chemical Name:    2,6-Dimethylphenol

    Synonyms:   Xylenol


    Molecular
     Formula:   C8H10O .
                       OH
    Structure:    CH3
    Chemical Properties

       Molecular Weight:   122.18

       Vapor Pressure:

       Boiling Point:  212°C at 760mm

       Density:    0.984 at 60DC/15.5°C

       Octanol/Water Parti-
        tion Coefficient:   2.33

    E nvironmental Penistence

       BOO:

       Atmospheric Reactivity:
Physical State:  Solid

Vapor Density:

Melting Point:  49°C

Solubility:  Soluble (H2O)
    Safety Hazard:
                                            AIV-304

-------
                                                                         2, 6-Xylenol
                               PRODUCTION DATA

Annual U.S.
 Production:                                   Consumption:

Fraction of                                     Fraction of Pro-
 Dispersion:                                      duction Lost:

Release Rate (million Ibs/yr):
                                 TOXICITY DATA

Acute Toxicity               Dosage               Animal              Route
       LDSO  .             296mg/kg             rat                 oral
                          980 mg/kg             mouse              oral
                          920 mg/kg             mouse              skin
                          150 mg/kg             mouse              intraperitoneal
                          700 mg/kg             rabbit               oral
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA: 100 ppm
   Carcinogenicity:
       Neoplastic effects:
         TDLo           4000 mg/kg (120 weeks)    mouse              skin
   Mutagenicity:

   Teratogenicity:                               tLV:
                                              Odor perception: 200 ppm
   Other Chronic Effects:
                                       AIV-305

-------
3, 5-Xylenol
                                     CHEMICAL NAME
    CAS Number:     1300-71-6

    Chemical Name:   Dimethylphenol

    Synonyms:    Xylenol
                 3,5-Xylenol
                 5-Hydroxy-l, 3-dimethylbenzene
    Molecular
     Formula:    C8H10O
  3,5-Dimethylphenol
  l-Hydroxy-3,5-dimethylbenzene
    Structure:
    Chemical Properties

       Molecular Weight:    122.17

       Vapor Pressure:   1 mm at 62.0°C

       Boiling Point:  219.5°C (sublimes)

       Density:   0.9680 at 20°C/4°C

       Octanol/Water Parti-
        tion Coefficient:

    Environmental Persistence

       BOD:    31% of theoretical

       Atmospheric Reactivity:
Physical State:    Solid

Vapor Density:

Melting Point:    68°C

Solubility:    Soluble (H2O)
    Safety Hazard:
            Fiie-slight
                                             AIV-306

-------
                                                                        3, 5-Xylenol

                              PRODUCTION DATA
Annual U.S.
 Production:                                   Consumption:

Fraction of                                    Fraction of Pro-
 Dispersion:                                    duction Lost:

Release Rate (million Ibs/yr):
                                TOXICITYDATA

Acute Toxicity              Dosage               Animal              Route
       LD5o              1070 mg/kg            mouse              oral
                         1750 mg/kg            guinea pig           subcutaneous
Chronic Toxicity

   U.S. Occupational Standard:  (air) TWA: 100 ppm



   Carcinogenicity:


   Mutagenicity:

   Teratogenicity:                               TLV:

   Other Chronic Effects:
                                     AIV-307

-------
Zinc stearate
                                     CHEMICAL  NAME
    CAS Number:    557-05-1

    Chemical Name:     Octadecanoic acid, zinc salt

    Synonyms:      Stearic acid, zinc salt
    Molecular
      Formula:      (ci8H35°2*2 °Zn
    Structure:    [CH3(CH2)lfi COO"] 2 Zn2
    Chemical Properties

       Molecular Weight:   632.30

       Vapor Pressure:

       Boiling Point:

       Density:  1.095

       Octanol/Water Parti-
         tion Coefficient:

    Environmental Persistence

       BOO:

       Atmospheric Reactivity:
    Safety Hazard:
              Fire-slight
Physical State:   Solid

Vapor Density:

Melting Point:    130°C

Solubility:    Insoluble (H2O)
                                            AIV-308

-------
                                                                       Zinc  stearate
Annual U.S.
 Production:     19.4 x 106 Ibs.
Fraction of
 Dispersion:
1.0
PRODUCTION DATA


               Consumption:    19.4 x 106 Ibs.

               Fraction of Pro-
                 duction Lost:     0.03
Release Rate (million Ibs/yr):  20.0
Acute Toxicity


Non-lethal Acute Effects:
    Pulmonary fibrosis
                  TOXICITY DATA

            Dosage               Animal
                                    Route
Chronic Toxicity

   U.S. Occupational Standard:



   Carcinogen icity:


   Mutagenicity:

   Teratogenicity:

   Other Chronic Effects:
                               TLV:
                                      AIV-309

-------
                      CHEMICAL NAME INDEX
Acenaphthylene                                               AI-2
Acetaldehyde                                                 AI-6
Acetamide                                                    AI-10
Acetanilide                                                  AI-14
Acetic acid                                                  AI-16
Acetic acid, butyl ester                                     AI-160
Acetic acid, sec butyl ester                                 AI-162
Acetic acid, decyl ester                                     AII-90
Acetic acid, 1,1-dimethylethyl ester                         AI-164
Acetic acid, ethyl ester                                     AII-234
Acetic acid, isobutyl ester                                  AIII-62
Acetic acid, methyl ester                                    AIII-148
Acetic acid, 1-methylethyl ester                             AIII-84
Acetic acid, pentyl ester                                    AI-64
Acetic acid, propyl ester                                    AIV-108
Acetic acid, sodium salt                                     AIV-140
Acetic anhydride                                             AI-18
Acetoacetic acid, ethyl ester                                AIIr-236
Acetoacetic acid, methyl ester                               AIII-150
Acetone                                                      AI-20
Acetonitrile                                                 AI-24
3-(a-Acetonylbenzyl)-4-hydroxycoumarin                       AIV-294
Acetophenone                                                 AI-26
Acetylene                                                    AI-28
Acrolein                                                     AI-34
Acrylamide                                                   AI-36
Acrylic acid                                                 AI-38
Acrylic acid, butyl ester                                    AI-166
Acrylic acid, ethyl ester                                    AII-238
Acrylonitrile                                                AI-40
Adipic acid                                                  AI-42
Adipic acid, bis(2-ethylhexyl)ester                          AII-104
Allyl alcohol                                                AI-48
1-Allylnaphthalene                                           AI-54
o-Aminobenzenesulfonic acid                                  AIV-162
p-Aminobenzoic acid                                          AI-58
3-Amino-2,5-dichlorobenzoic acid                             AI-56
2-Aminoethanol                                               AII-230
2-[(2-Aminomethyl)amino]-ethanol                             AI-62
4-[(4-Aminophenyl)(4-imino-2,5-cyclohexadien-l-ylidene)-
  methyl]-2-methyl benzenamine                               AIII-112
4-Amino-3,5,6-trichloropicolinic acid                        AIV-52
Aniline                                                      AI-78
Anilidine hydrochloride                                      AI-80
                              AIV-310

-------
                CHEMICAL NAME INDEX (Continued)
o-Anisidine                                               AI-82
p-Anisidine                                               AI-82
Anisole                                                   AI-84
Anthranilic acid                                          AI-86
Anthraquinone    .                                         AI-88
Aroclor 1254 and 1260                                     AIV-66
Benzaldehyde                                              AI-98
Benzamide                                                 AI-100
Benzene                                                   AI-102
1,2-Benzenedicarboxylic acid,
  bis (8-methylnonyl)ester                                AII-122
1,2-Benzenedicarboxylic acid, dioctyl ester               AII-124
m-Benzene disulfonic acid                                 AI-104
Benzene methanamine                                       AI-130
Benzene sulfonic acid                        ,             AI-106
Benzidine                                                 AI-108
Benzil                                                    AI-110
Benzilic acid                                             AI-112
Benzoic acid                                              AI-114
Benzoic acid, benzyl ester                                AI-134
Benzoic acid, sodium salt                                 AIV-142
Benzoin                                                   AI-116
Benzonitrile                                              AI-118
Benzophenone                                              AI-120
p-Benzoquinone                                            AI-122
Benzoyl chloride                                          AI-126
Benzyl alcohol                                            AI-128
Biphenyl                                                  AII-182
4-Biphenyl amine                                          AI-60
Bis-(2-butoxyethyl)ether                                  AII-82
N,N-Bis(carboxymethyl)glycine, trisodium salt             AIII-258
Bis(2-chloroethyl)ether                                   AII-50
Bis(a,a-dimethylbenzyl)peroxide                           AII-68
Bis(dimethylthiocarbamoyl)disulfide                       AIV-206
Bis(2-ethoxyethyl) ether                                  AII-84
2,2-Bis(hydroxymethyl)-1,3-propanediol                    AIV-18
Bis-(2-methylpropyl)carbamothioic acid, S-ethyl ester     AIV-168
Bromobenzene                                              AI-146
5-Bromo-3-sec-butyl-6-methyluracil                        AI-144
Bromomethane                                              AII-248
Bromomethane                                              AIII-166
2-Bromonaphthalene                                        AI-148
1,3-Butadiene                                             AI-150
(S)2-Butanamine                                           AI-176
Butane                                                    AI-152
1,3-Butanediol                                            AI-184
1-Butanethiol                                             AI-188
                            AIV-311

-------
                 CHEMICAL NAME INDEX (Continued)
2-Butanone                                                AIII-192
1-Butene                                                  AI-154
2-Butene                                                  AI-156
Butene, homopolymers                                      AIV-64
2-Butoxyethanol                                           AI-158
a-[2-(2-Butoxyethoxy)ethoxy]-4,5-(methylenedioxy)-
  2-propyltoluene                                         AIV-58
(Butoxymethyl)oxirane                                     AI-186
Butyl alcohol                                             AI-168
sec-Butyl alcohol                                         AI-170
tert-Butyl alcohol                                        AI-172
t-Butylamine                                              AI-178
p-tert-Butylphenol                                        AI-190
p-tert-Butyltoluene                                       AI-192
Butyraldehyde                                             AI-174
Butyric acid                                              AI-194
Butyric anhydride                                         AI-196
Butyronitrile                                             AI-198
Calcium propionate                          ,              AI-204
Camphor                                                   AI-208
Carbamic acid, 2,3-dihydro-2,2-dimethyl-
  7-benzofuranyl ester                                    AI-216
Carbondisulfide                                           AI-218
4,4'-Carbonimidoyl bis[N,N-dimethyl]benzenamine           AI-90
Carbon tetrabromide                                       AI-220
Carbon tetrachloride                                      AI-222
Castor oil                                                AI-224
Cellulose acetate                                         AI-226
Cellulose, carboxymethyl ether, sodium salt               AIV-144
Cellulose, ethyl ether                                    AII-252
Chloroacetaldehyde                                        AI-232
Chloroacetic acid                                         AI-234
Chloroacetic acid, ethyl ester                            AII-256
Chloroacetic acid, sodium salt                            AIV-146
2-Chloroacetophenone                                      AI-236
m-Chloroaniline                                           AI-238
o-Chloroaniline                                           AI-240
p-Chloroaniline                                           AI-242
2-Chloro-4,6-bis(ethylamino)-s-triazine                   AIV-90
2-Chloro-4,6-bis(isopropylamino)-s-triazine               AIV-100
o-Chlorobenzaldehyde                                      AI-244
p-Chlorobenzaldehyde                                      AI-246
Chlorobenzene                                             AI-248
Chlorobenzoic acid (2,3, and 4)                           AI-252
o-Chlorobenzoyl chloride                                  AI-254
o-Chlorobenzylidene malonitrile                           AI-256

                           AIV-312

-------
                  CHEMICAL NAME INDEX (Continued)
                                                             Page
3-Chloro-l,3-butadiene
m-Chlorocarbanilic acid, isopropyl ester
2-Chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
Chlorodifluoroethane
Chlorodifluoromethane
l-Chloro-2,3-epoxypropane
Chloroethane
2-Chloroethanol
2-Chloro-4-ethylamino-6-isopropylamino-s-triazine
Chloroethylene
Chloroethylene, polymers
Chloroform
Chloromethane
2-Chloro-N-(1-methylethyl)-N-phenylacetamide
3-Chloro-2-methylpropene
1-Chloronaphthalene
1-Chloro-3-nitrobenzene
l-Chloro-2-nitrobenzene
l-Chloro-4-nitrobenzene
1-Chloro-l-nitropropane
1-Chloropentane
m-Chlorophenol
p-Chlorophenol
p-Chlorophenol
1-Chloropropane
2-Chloropropane
2-Chloro-l-propanol
3-Chloropropene
a-Chlorotoluene
m-Chlorotoluene
o-Chlorotoluene
p-Chlorotoluene
C.I. Solvent Yellow 2
Citric acid
Coal tar naphtha
m-Cresol
o-Cresol
p-Cresol
(E)-Crotonaldehyde
Crotonic acid
Cumene
Cyanoacetic acid
Cyanoacetic acid, ethyl ester
Cyanogen chloride
Cyclohexane
AI-282
AI-284
AI-44
AI-258
AI-260
AII-224
AII-254
AII-264
AI-262
AIV-288
AIV-88
AI-264
AIII-174
AIV-92
AIII-136
AI-266
AI-268
AI-270
AI-272
AI-274
AI-70
AI-276
AI-278
AI-280
AIV-114
AIII-90
AIV-118
AI-50
AI-136
AI-286
AI-288
AI-290
AII-138
AI-292
AIII-238
AI-296
AI-298
AI-300
AI-302
AI-304
AI-306
AI-310
AII-258
AI-312
AI-318
                             AIV-313

-------
                 CHEMICAL NAME INDEX (Continued)
Cyclohexanol
Cyclohexanone
Cyclohexene
4-Cyclohexene-l,2-dicarboxylic acid
Cyclohexylamine
1,3-Cyclopentadiene
Decahydronaphthalene
Decyl alcohol
N,N-diethy1-m-toluamide
N,N-dially1-2-chloroacetamide
3,5-Diaminobenzoic acid
Diazomethane
1,2-Dibromo-3-chloropropane
1,2-Dibromomoethane
Dibromodifluoromethane
2,6-Di-tert-butyl-p-cresol
2,4-Dichloroaniline
3,4-Dichloroaniline
o-Dichlorobenzene
p-Dichlorobenzene
3,3'-Dichlorobenzidine
Dichlorodifluoromethane
1,3-Dichloro-5,5-dimethylhydantoin
1,1-Dichloroethane
1,2-Dichloroethane
1,1-Dichloroethylene
1,2-Dichloroethylene (Z and E)
4,4'-Dichlorobenzilic acid, ethyl ester
Dichlorofluoromethane
Dichloromethane
3,6-Dichloro-2-methoxybenzoic acid
1,5-Dichloropentane
(2,4-Dichlorophenoxy)acetic acid
2- ( 2,4-Dichlorophenoxy)ethanol,hydrogensulfate,
  sodium salt
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
3-(3,4-Dichlorophenyl)-1-inethoxy-l-methylurea
N-(3,4-Dichlorophenyl)propanamide
1,2-Dichloropropane
l,3-Dichloro-2-propanol
1,3-Dichloropropene
2,2-Dichloropropionic acid, sodium salt
Dichlorotetrafluoroethane
a,o-Dichlorotoluene
4,4'-Dichloro-a-(trichloromethy1)benzhydrol
Dicyclohexylamine
AI-320
AI-322
AI-324
AIV-192
AI-326
AI-328
AII-12
AII-14
AII-16
AIV-128
AII-22
AII-26
AII-8
AII-268
AII-28
AII-30
AII-34
AII-36
AII-38
AII-40
AII-42
AII-44
AII-46
AII-312
AII-270
AIV-290
AII-48
AI-250
AII-52
AIII-186
AI-94
AII-56
AII-58

AI-294
AI1-200
AIII-110
AIV-96
AII-60
AII-54
AII-62
AII-4
AII-64
AI-138
AII-66
AII-70
                           AIV-314

-------
                   CHEMICAL NAME INDEX (Continued)
Diethylacetal acetaldehyde
Diethylamine
2-(Diethylamino)ethanol
Diethyleneglycol
2,2'-Diethylenetriamine
a,a-Diethyl-4,4'-stilbenediol
1,1-Difluoroethane
1,2-Dihydro-3,6-pyridazinedione
1,2-Dihydro-2,2,4-trimethylquinoline
Diisobutylene
DiisopropyIamine
3,3'-Dimethoxybenzidine
D ime thoxyme thane
(E)-3[(Dimethoxyphosphinyl)oxy]-2-butenoic acid,
  methyl ester
Dimethylacetal acetaldehyde
N,N-Dimethylacetamide
DimethyIamine
N,N-Dimethylaniline
3,3'-DimethyIbenzidine
a, ot-Dimethy Ibenzylhydroperoxide
1,1'-Dimethy1-4,4'-bipyridium dichloride
1,3-Dimethylbutyl acetate
(1,1-Dimethylethyl) benzoic acid
N,N-DimethyIformamide
1,1-Dimethylhydrazine
1,2-Dimethylhydrazine
2,6-Dimethyl-4-heptanone
N-(1,4-Dimethylpentyl)-N'phenyl-p-phenylene-diamine
2,6-Dimethylphenol
3,5-Dimethylphenol
N,N-Dimethyl-a-phenylbenzeneacetamide
0,0-Dimethylphosphorodithioic acid,
  O-(p-nitrophenyl)ester
1,l-Dimethyl-3-(a,a,a-trifluoro-m-tolyl)urea
1,2-Dinitrobenzene
1,3-Dinitrobenzene
1,4-Dinitrobenzene
2,4-Dinitrobenzoic acid
Dinitrophenol
2,4-Dinitrotoluene
p-Dioxane
1,3-Dioxolane
1,3-Dioxolan-2-one
Diphenylamine
AI-4
AII-76
AII-78
AII-80
AII-102
AII-108
AII-112
AIII-120
AII-116
AII-118
AII-126
AII-132
AIII-152

AIII-224
AII-280
AII-134
AII-136
AII-140
AIV-208
AI-308
AIV-12
AII-142
AI-180
AII-146
AII-148
AII-150
AII-120
AII-152
AIV-304
AIV-306
AII-180

AIII-214
AIII-6
AII-164
AII-164
AII-164
AII-166
AII-170
AII-172
AII-176
AII-178
AII-262
AII-184
                           AIV-315

-------
                 CHEMICAL NAME INDEX (Continued)
Diphenylmethane                                           AI-132
Dipropylcarbamothioic acid, S-propyl ester                AIV-284
Dipropylene glycol                                        AII-190
Dipropylene glycol, monomethyl ether                      AII-192
1,la,2,2,3,3a,4,5,5,5a,5b,6-Dodecachloro-
  octahydro-l,3,4-metheno-lH-cyclobuta(Cd) pentalene      AIII-226
Dodecane                                                  AII-202
1-Dodecanethiol                                           AII-208
1-Dodecene                                                AIV-202
Dodecyl benzene                                           .AII-204
Dodecylbenzenesulfonic acid, sodium salt                  AII-206
Dodecylguanidine, monoacetate                             AI-330
Dodecylphenol                                             AII-210
Ethane                                                    AII-228
Ethanethiol                                               AII-314
Ethanol                                                   AII-240
Ethanol, homopolymers                                     AIV-86
2-Ethoxyethanol                                           AII-286
2-Ethoxyethanol acetate                                   AII-288
2-(2-Ethoxyethoxy)ethanol                                 AII-92
2-(2-Ethoxyethoxy)ethanol acetate                         AII-94
Ethanamine                                                AII-242
Ethylbenzene                                              AII-246
Ethylbenzene, homopolymer                                 AIV-80
S-Ethyldipropylthiocarbamate                              AII-226
Ethylene                                                  AII-261
Ethylene bis(dithiocarbamic acid), disodium salt          AIII-234
Ethylene glycol                                           AII-272
Ethylene glycol, diacetate                                AII-274
Ethylenediamine                                           AII-266
Ethylene glycol, diethyl ether                            AII-278
Ethylene glycol, monoacetate                              AII-282
Ethylene oxide        "                                    AII-304
Ethylene, polymers                                        AIV-68
Ethyleneimine                                             AII-302
Ethyl ether                                               AII-306
2-Ethyl-l-hexanol                                         AII-310
4-Ethylmorpholine                                         AII-318
1-Ethylnaphthalene                                        AII-320
N-Ethyl-N-nitrosourea       .                              AIII-290
Ethylphosphonpdithioic acid,
  0-ethyl-S-phenyl ester                                  AII-218
Ferbam                                                    AIII-2
                           AIV-316

-------
                  CHEMICAL NAME INDEX (Continued)
Ferrocene
N-Fluoren-2-yl-acetamide
Formaldehyde
Formamide
Formic acid
Formic acid, ethyl ester
Formic acid, methyl ester
Formic acid, sodium salt
Furmaric acid
2-Furaldehyde
Furfuryl alcohol
D-Glucitol
L-Glutamic acid, monosodium salt
Glycerol
Glycine
Glyoxal
Guanidine
1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,
  7-methanoindene
3-Heptanone
3-Heptene (Z and E)
1,2,3,4,5,6-Hexachlorocyclohexane(gamma isomer)
1,2,3,4,10,10-Hexachloro-6,7-epoxy-l,4,4a,5,6,7,
  8,8a-octahydro-l,4,5,8-dimethanonaphthalene
Hexachloroethane
1,2,3,4,10,10-Hexachloro-l,4,4a,5,8,8a-hexahydro-
  1,4,5,8-dimethanonaphthalene
Hexachloronaphthalene
1,4,5,6,7,7-Hexachloro-5-norbornene-2,
  3-dimethanol, cyclic sulfite
Hexahydro-2H-azepin-2-one
3-(Hexahydro-4,7-methanoindan-5-yl)-1,
  1-dimethylurea
Hexamethylenetetramine
1,6-Hexanediamine
1,6-Hexanediol
2-(Hexyloxy)ethanol
2-[2-(Hexyloxy)ethoxy]ethanol
Hydrocyanic acid
a-Hydro-0-hydroxypoly[oxy(methyl-1,2-ethanediyl)
Hydroquinone
3-Hydroxybutyraldehyde
Hydroxymethyl arsine oxide
4-Hydroxy-4-methyl-2-pentanone
AIII-4
AI-12
AIII-12
AIII-14
AIII-16
AII-308
AIII-194
AIV-148
AIII-18
AIII-20
AIII-22
AIV-154
AIII-228
AIII-24
AIII-30
AIII-32
AIII-34

AIII-38
AII-250
AIII-40
AIII-108

AII-72
AIII-44

AI-46
AIII-46

AII-220
AI-210
AIII-50
AIII-52
AIII-48
AII-290
AII-96
AIII-54
AIV-78
AIII-56
AI-8
AI-202
AII-20
                           AIV-317

-------
                  CHEMICAL NAME INDEX (Continued)
2,2*-Iminodiethanol
IH-Indene
lodomethane
Isopentyl alcohol
2-(2-Isobutoxyethoxy)ethanol
Isobutyl alcohol
Isobutyraldehyde
Isobutyric acid
Isocyanic acid, methyl ester
Isocyanic acid,i2-methy 1-m-phenylene ester
Isodecyl alcohol
IH-Isoindole-l,3(2H)-dione
Isooctanol
Isooctyl alcohol
26-(Isooctylphenoxy)-3,6,9,12,15,18,21,24-
  octaoxahexacosan-1-ol
Isophthalic acid
Isoprene
Isopropyl alcohol
Isopropylamine
Isopropyl ether
4,4'-Isopropylidenediphenol
o-Isopropyl phenol
p-Isopropyl phenol
Ketene
Ligninsulfohic acid, ammonium salt
Ligninsulfonic acid, calcium salt
Ligninsulfonic acid, sodium salt
Ligninsulfonic acid, ferrochrome salt
Maleic acid
Maleic anhydride
Malic acid (DL,D and L)
Melamine
Mercaptosuccinic acid, diethyl ester, S-ester with
  0,0-dimethyl phosophorodithioate
Methacrylic acid
Methacrylic acid, methyl ester
Methacrylonitrile
Methane
Methane arsonic acid
Methanearsonic acid, disodium salt
Methanearsonic acid, monosodium salt
Methanesulfonic acid, ethyl ester
Methanethiol
Methanol
AII-74
AIII-58
AIII-198
AIII-60
AII-88
AIII-64
AIII-66
AIII-70
AIII-204
AIV-214
AIII-72
AIV-46
AIII-74
AIV-2

AIII-76
AIII-80
AIII-82
AIII-86
AIII-88
AIII-92
AI-142
AIII-94
AIII-96
AIII-98
AIII-100
AIII-102
AIII-106
AIII-104
AIII-116
AIII-118
AIII-122
AIII-124

AIII-114
AIII-130
AIII-208
AIII-132
AIII-138
AIII-140
AII-194
AIII-232
AII-316
AIII-206
ALII-154
                           AIV-318

-------
               CHEMICAL NAME INDEX (Continued)
2-Methoxyethanol
2-Methoxyethanol acetate
2-(2-Methoxyethoxy)ethanol
2-(2-Methoxyethoxy)ethanol acetate
2-[-2-(2-Methoxyethoxy)ethoxy]ethanol
l-Methoxy-4-nitrobenzene
Methylamine
N-([(Methylamino)carbonyl]oxy)ethanimidothioic acid,
  methyl ester
N-Methylaniline
2-Methylaziridine
a-Methylbenzenemethanol
a-Methylbenzyl alcohol
2-Methyl-2-butene
Methyl-1-n-butyl ketone
3-(1-MethyIbutyl)phenol methylcarbamate
2-Methyl-3-butyn-2-ol
Methylcarbamic acid, 1-naphthyl ester
3-Methylcholanthrene
Methylcyclohexane
Methylcyclohexanol
2-Methylcyclohexanone
2-Methyl-4,6-dinitrophenol
Methyldioxolane  ,
4,4'-Methylene bis(2-chloroaniline)
4,4'-Methylenedianiline
4-Methylene-2-oxetanone
Methyl ether
Methyl ether cellulose
4-Me thy1-3-heptanone
5-Methyl-2-hexanone
Methylhydrazine
2-Methyl lactonitrile
2-Methyl-2-(methylthio)propionaldehyde-0-
  methyl-carbamoyl)oxime
Methylnaphthalene
N-Methyl-N'-nitro-N-nitrosoguanidine
N-Methyl-N-nitrosourea
2-Methyl-2,4-pentanediol
Methylamyl alcohol
4-Methy1-2-pentanol, acetate
4-Methy1-2-pentanone
4-Methyl-3-penten-2-one
3-Methyl-l-pentyn-3-ol
AIII-146
AII-294
AII-98
AII-100
AIV-268
AIII-262
AIII-156

AIII-142
AIII-162
AIV-122
AIII-220
AIII-164
AIV-22
AIII-168
AI-200
AIII-170
AI-214
AIII-176
AIII-178
AIII-180
AIII-182
AII-168
AIII-190
AIII-184
AIII-188
AII-128
AII-144
AIII-172
AII-244
AIII-200
AIII-196
AI-22

AIV-176
AIII-210
AIII-212
AIII-292
AIII-216
AIII-160
AIII-158
AIII-202
AIII-128
AIII-218
                             AIV-319

-------
               CHEMICAL NAME INDEX (Continued)
Methylphosphoramidic acid, 4-tert-butyl-2-
  chlorophenylmethyl ester
1-Methylpropene
2-Methyl-l-propene
2-Methyl-l-propene, homopolymer
2-Methyl-2-propen-l-ol
2-(l-Methylpropyl)-4,6-dinitrophenol
a-Methylstyrene
p-Me thyIs tyrene
Methylsulfide
4-(Methylsulfonyl)-2,6-dinitro-N,N-dipropylaniline
Methylsulfoxide
N-methyl-N,2,4,6-tetranitroaniline
Monostearin
Morpholine
Naphthalene
1-Naphthalenesulfpnic acid
2-Naphthalenesulfonic acid
1-Naphthol
2-Naphthol
1-Naphthylamine i
2-Naphthylamine
2-[(l-Naphthalenylamino)carbonyl]benzoic acid,
  monosodium salt
Nitrate cellulose
2,2?,2"-Nitrilotriethanol
p-Nitroaniline
Nitrobenzene
p-Nitrobenzoic acid
Nitroethane
Nitroglycerine
Nitromethane
o-Nitrophenol
3-Nitrophenol
p-Nitrophenol
1-Nitropropane
2-Nitropropane
N-Nitrosodiethylamine
N-Nitrosodimethylamine
m-Nitrotoluene
o-Nitrotoluene
p-Nitrotoluene
Nonene
Nonoylphenol
1,2,4,5,6,7,8,8-Octachloro--3a,4,7,7a-tetrahydro-4,
  7-methanoindan
AIV-134
AI-182
AIII-68
AIV-272
AIII-134
AII-174
AIII-222
AIV-292
AII-158
AIV-60
AII-160
AIV-204
AIII-26
AIII-230
AIII-240
AIII-242
AIII-244
AIII-246
AIII-248
AIII-250
AIII-252

AIII-254
AIII-268
AIV-260
AIII-260
AIII-264
AIII-266
AIII-270
AIII-272
AIII-274
AIII-278
AIII-276
AIII-280
AIII-282
AIII-284
AIII-286
AIII-288
AIII-294
AIII-296
AIII-298
AIII-300
AIII-302

AI-230
                           AIV-320

-------
                 CHEMICAL NAME INDEX (Continued)
Octadecanoic acid, zinc salt
2-(Octyloxy)ethanol
Octylphenol
7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic acid
Oxalic acid
Oxalic acid, diethyl ester
2-Oxetanone
1,1'-Oxybis[2-methoxyethahe]
Oxybis(chloromethane)
Pentachloronitrobenzene
Pentachlorophenol
Pentane
1-Pentanethiol
1-Pentene
Pentyl alcohol
Pentylamine
Pentyl ether
o-Phenetidine
p-Phenetidine
Phenol
Phenol, sodium salt
Phenothiazine
2-Phenoxyethanol
o-Phenylenediamine
p-Phenylenediamine
Phenyl ether
Phenylhydrazine
Phosgene
Phosphoric acid, l,2-dibromo-2,2-dichloroethyl
  dimethyl ester
Phosphoric acid, (Z)dimethy1-1-methy1-3(methylamino)-
  2-oxo-l-propenyl ester
Phosphoric acid, tributyl ester
Phosphoric acid, tri-o-tolyl ester
Phosphorodithioic acid, S-[[(p-chlorophenyl)thio]
  methyl]-0,0-diethyl ester
Phosphorodithioic acid, 0,0-diethyl-S-[2(ethylthio)
  ethyl] ester
Phosphorodithioic acid, 0,0-diethy1-0-(3,5,6-
  trichloro-2-pyridinyl) ester
Phosphorodithioic acid, 0,0-dimethyl ester, S-ester
  with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one
AIV-308
AII-296
AIV-6
AII-222
AIV-8
AII-322
AIV-102
AII-86
AI-140
AIV-14
AIV-16
AIV-20
AI-76
AI-72
AI-66
AI-68
AI-74
AIV-28
AIV-30
AIV-32
AIV-150
AIV-34
AII-298
AIV-38
AIV-40
AII-186
AIV-36
AIV-42

AIII-236

AI-92
AIV-232
AIV-256

AIV-280

AII-196

AII-216

AIII-36
                           AIV-321

-------
                CHEMICAL NAME INDEX (Continued)
Phosphorodithioic acid, S-ester with 2-mercapto-N-
  methylacetamide 0,0-dimethyl ester                         AII-130
Phosphorodithioic acid, S,S'-methylene 0,0,0',0'-
  tetraethyl ester                                           AII-232
Phosphorothioic acid, 0,0-diethyl-0-(2-isopropyl-6-
  methyl-4-pyrimidyl) ester                                  AII-24
Phosphorothioic acid, 0,0-diethyl-0-[p-(methylsulfinyl)      	
  phenylJester                                               AII-6
Phosphorothioic acid, 0,0-diethyl-0-(p-nitrophenol)
  ester                                                      AII-324
Phosphorothioic acid, 0,0-dimethy1-0-(2,4,5-
  trichlorophenyl)ester                                      AIV-132
Phosphorotrithious acid, tributyl ester                      AIII-8
Phthalic acid, bis(2-ethylhexyl)ester                        AII-106
Phthalic acid, decyl octyl ester                             AIV-4
Phthalic acid, dibutyl ester                                 AII-32
Phthalic acid, dimethyl ester                                AII-154
Phthalic acid, ditridecyl ester                              AII-198
Phthalic anhydride                                           AIV-44
Phthalonitrile                                               AIV-48
B-Picoline                                                   AIV-50
Piperazine                                                   AIV-56
Pivalic acid                                                 AIII-256
Polyethylene glycol chloride                                 AIV-72
Polyethylene glycols                                         AIV-70
Poly(oxy-1,2-ethanediyloxycarbonyl-l,
  4-phenylenecarbonyl)                                       AIV-74
Polystyrene, thermoplastic resins                            AIV-80
Propane                                                      AIV-94
1,2-Propanediol                                              AIV-120
2-Propenamide, homopolymer                                   AIV-62
Propene                                                      AIV-116
1-Propene, homopolymer                                       AIV-76
Propene oxide                                                AIV-124
Propionaldehyde                                              AIV-104
Propionic acid                                               AIV-106
2-Propoxyethanol                                             AII-300
Propyl alcohol                                               AIV-110
Propylamine                                                  AIV-112
Propyne                                                      AI-52
2-Propyn-l-ol                                                AIV-98
Pyridine                                                     AIV-126
Resorcinol                                                   AIV-130
Salicylic acid                                               AIV-136
Silicic acid, tetraethyl ester                               AII-326

                            AIV-322

-------
                CHEMICAL NAME INDEX (Continued)
Sorbic acid                                                  AIV-152
Stearic acid, calcium salt                                   AI-206
Styrene                                                      AIV-156
Succinic acid .     	                                   AIV-158
Succinonitrile                                               AIV-160
Sulfobutanedioic acid, l,4-bis(2-ethylhexyl)ester,
  sodium salt                           '                     AIV-166
Sulfuric acid, diethyl ester                                 AII-110
Sulfuric acid, dimethyl ester                                AII-156
Sulfuric acid, monodbdecyl ester, compounded with
  2,2',2"-nitrilotris[ethanol](l:l)                          AII-214
Sulfuric acid, monododecyl ester, sodium salt                AII-212
Terephthalic acid                                            AIV-174
Terephthalic acid, dimethyl ester                            AII-162
2,3,5,6-Tetrachloro-p-benzoquinone                           AI-228
1,1,2,2-Tetrabromoethane                                     AI-30
2,3,5,6-Tetrachloro-l,4-benzenedicarboxylic acid,
  dimethyl ester                                             AII-2
1,1,1,2-Tetrachloro-2,2-difluoroethane                       AIV-180
l,l,2,2-Tetrachloro-l,2-difluoroethane                       AIV-178
1,1,2,2-Tetrachloroethane                                    AI-32
Tetrachloroethylene                                          AIV-24
N-(1,1,2,2-Tetrachloroethylthio)-4-cyclohexone-l,
  2-dicarboximide                                            AII-114
1,2,3,4-Tetrachloro-l,2,3,4-tetrahydronaphthlene             AIV-182
Tetrachlorophthalic anhydride                                AIV-184
Tetraethylplumbane                                           AIV-186
Tetrafluoroethene                                            AIV-84
Tetrahydrofuran                                              AIV-188
1,2,3,4-Tetrahydronaphthalene                                AIV-190
Tetrahydrothiophene-l,l-dioxide                              AIV-164
N,N,N',N'-Tetramethyl-ethylenediamine                        AIV-194
Tetramethylplumbane                                          AIV-196
Tetramethyl succinonitrile                                   AIV-198
Tetranitromethane                                            AIV-200
2,5,8,11-Tetraoxadodecane                                    AIV-266
Thiocarbanilide                                              AII-188
Toluene                                                      AIV-210
Toluene-2,4-diamine                                          AIV-212
p-Toluenesulfonylamide                                       AIV-216
o-Toluenesulfonic acid                                       AIV-218
p-Toluenesulfonic acid                                       AIV-220
p-Toluenesulfonyl chloride                                   AIV-222
m-Toluidine                                                  AIV-224
o-Toluidine                                                  AIV-226

                             AIV-323

-------
                  CHEMICAL  NAME INDEX (Concluded)
 p-Toluidine
 Toxaphene
 s-Triazine-2,4,6-triol                        	
~S,S,S,-Tributyl phosphorotrithioate
 Trichloroacetic acid
 2,4,6-Trichloroaniline
 3,5,6-Trichloro-o-anisic  acid
 1,2,4-Trichlorobenzene
 2,3,6-Trichlorobenzoic acid
 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane
 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane
 1,1,1-Trichloroethane
 1,1,2-Trichloroethane
 Trichloroethylene
 Trichlorofluoromethahe
 Trichloromethanethiol
 N(Trichloromethyl)thio-4-cyclohexene-l,
   2-dicarboximide
 N-[(Trichloromethyl)thio]phthalimide
 1,4,6-Trichloronaphthalene
 (2,4,5-Trichlorophenoxy)acetic acid
 2-(2,4,5-Trichlorophenoxy)propionic  acid
 1,2,3-Trichloropropane
 a,a^a-Trichlorotoluene
 2,4,6-Trichloro-s-triazine
 1,3,5-Trichloro-s-triazine-2,4,6-(1H,3H,5H)-trione
 1,1,2-Trichloro-l,2,2-Trifluoroethane
 p-Tridecylbenzenesulfonic acid, sodium salt
 Triethylamine
 Triethylene glycol
 a,a,a-Trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine
 Trimethylamine
 1,3,4-Trimethylbenzene
 2,6,6-Trimethylbicyclo(3.1.l)hept-l-ene
 2,6,6-Trimethylbicyclo(3.1.l)hept-2-ene
 3,5,5-Trimethyl-2-cyclohexen-l-one
 2,2,4-Trimethyl-l,3-pentanediol
 2,4,6-Trimethyl-S-trioxane
 2,4,6-Trinitrotoluene
 Urea
 Vinyl acetate
 m-Xylene
 o-Xylene
 p-Xylene
 3,4-Xylenesulfonic acid,  sodium salt
AIV-228
AIV-230
AI-314
AII-18
AIV-172
AIV-234
AI-96
AIV-236
AIV-170
AII-10
AIII-144
AIV-240
AIV-238
AIV-242
AIV-244
AIV-26

AI-212
AIII-10
AIV-248
AIV-250
AIV-138
AIV-252
AI-124
AI-316
AIV-246
AIV-254
AIV-258
AIV-262
AIV-264
AIV-270
AIV-274
AIII-126
AIV-54
AIV-54
AIII-78
AIV-276
AIV-10
AIV-278
AIV-282
AIV-286
AIV-296
AIV-298
AIV-300
AIV-302
                               AIV-324

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                                    TECHNICAL REPORT DATA
                            (Please read Instructions on the reverse before completing)
 1. REPORT NO.
     EPA-450/3-77-OQ8e
                              2.
                                                            3. RECIPIENT'S ACCESSION-NO.
4. TITL
                  Scoring of  Organic Air Pollutants:
     Chemistry,  Production and  Toxicity of Selected
     Synthetic  Organic Chemicals
          icals  0-Z) Appendix  IV	
                                                            5. REPORT DATE
                                                                    October 1976
                                                            6. PERFORMING ORGANIZATION CODE
7. AUT
                                                            8. PERFORMING ORGANIZATION REPORT NO.
     J. Dorigan,  B.  Fuller,  R.  Duffy
9. PERFORMING ORGANIZATION NAME AND ADDRESS
     The Mitre Corporation
     Metrek Division
     Westgate Research Park
     McLean, Virginia  22101
                                                             10. PROGRAM ELEMENT NO.
                                                             11. CONTRACT/GRANT NO.
                                                                 68-02-1495
12. SPONSORING AGENCY NAME AND ADDRESS
     EPA, Office  of Air Quality  Planning and  Standards
     Strategies  and Air Standards Division
     Research  Triangle Park,  N.C.  27711
                                                             13. TYPE OF REPORT AND PERIOD COVERED
                                                            14. SPONSORING AGENCY CODE
15. SUPPLEMENTARY NOTES
16. ABSTRACT
          This  is the fourth  of a series of four appendices  to the report  "Scoring
     of Organic Air Pollutants."  The entire appendix contains a compilation  of
     available  data on chemical  structure  and properties,  environmental persistence,
     production, and toxicity for 637 synthetic organic chemicals.
17.
                                KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                                               b.IDENTIFIERS/OPEN ENDED TERMS  C.  COSATI Field/Group
     organic  chemical structure
     organic  chemical properties
     organic  chemical production
     organic  chemical toxicity
18. DISTRIBUTION STATEMENT
                                               19. SECURITY CLASS (ThisReport)
                                                  unclassified
                                                                          21. NO. OF PAGES

                                                                              331
     unlimited
                                               20. SECURITY CLASS (Thispage)
                                                  unclassified
                                                                           22. PRICE
EPA Form 2220-1 (9-73)

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