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Index to the Report of the Secretary's
Ccr^mission -on Pesticides and Their
r::s!afionshlp f© Environmental Health
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Ivefionsl Ubrary of Medicine, BefRejdis, Mt
r.^vironmeiit8i Pirotection Agency, Washington, D C Offks of Pesticide
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TOXICOLOGY INFORMATION PROGRAM
U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
Public Health Service
National Institutes of Health
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TOXICOLOGY INFORMATION PROGRAM
m
Index to the Report
of the
Secretary's Commission on Pesticides
and
Their Relationship
to
Environmental Health
by Sharon L. Valley, Ph. D.
Toxicology Information Program
National Library of Medicine
R."
v-1
U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
Public Health Service
National Institutes of Health
NATIONAL LIBRARY OF MEDICINE
8600 Rockville Pike
Bethesda, Maryland 2C014
-------
DHEW Publication No.(NIH)72-269
Tor ilk by the Superintendent of Documents, U.8. Qonrmnent Printing OBta
WMhlnfton,D.C.:
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TABLE OF CONTENTS
Page
INTRODUCTION «
•'- CHEMICAL SUBSTANCE INDEX 1-72
SUBJECT INDEX 73-205
•-- BIBLIOGRAPHY 207-310
II
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u
1
INTRODUCTION .-'
Y
The indexes in this publication were designed to assist users in rapidly finding Information in
The Report of the Secretary's Commission on Pesticides arj Their Relationship to
Environmental Health, published by the U.S. Government Printing Office, December 1969. •
This publication consists of three indexes: a Chemical Substance Index; a Subject Index, and a \
KWogrcfhy. V
J
The Chemical Substance Index and the Subject Index are arranged alphabetically by main
terms. Free text entries under each main term are arranged in increasing page number sequence.
Therefore, the user is encouraged to browse through these entries (under one or more main
terms) to assure that all concepts have been located.
The Bibliography is arranged alphabetically by first author; citations are presented as they were
published in the original Report. Duplicate citations were removed but annotated as follows:
number(s) in parenthesis after the citation indicate the Report page(s) on which the reference
was specifically cited and/or discussed within the text. Numbers following the citation.' at not
in parenthesis, indicate the Report poge(s) on which the reference was listed.
In order 'o prepare these indexes, the entire text of The Report of the Secretary's Commission
on Pesticides and Their Relationship to Environmental Health, including the references, was
entered into an on-line, whole text computer search system (Mead Data Central, Mead Data
Corporation). On-line, interactive indexing was performed using color cathode ray tube r- .riev U
equipment. The entire Report is still in an on-line system for search purposes.
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CHEMICAL SUBSTANCE INDEX
Subject
AATREX
Sec ATR/.ZINE
ABATE
Use in control of mosquito larvae 60
Replacement for DDT, selective 60
New pesticides 60
Organic phosphates 64
Importance in public health 64
Organic phosphate phenyl
derivatives 64
Use rates 64
Resistance, mosquitoes 127
ACARABEN
See CHLOROBENZILAIE
ACARALATE
See CHLORPROPYLATE
ACETYLCHOLINE
Effects of cholinestcrase
inhibitors 411
Behavioral effects 412
Effects on schizophrenics 418
Synergism, mechanisms 524
ACETYLETHYLENEIMINE
Chromosome aberrations in
higher plants 583
PIN-ACETYL-METHYL-
PIIOSPHONOFLUORIDATE
SeeSEMAN
ACRITET
See ACRYLONITRILE
ACROLEIN
Herbicides, Miscellaneous 70
Toxicity 70
Uses 70
Tentative guidelines for
herbicides 124
Tentative guidelines for crops 1 24
Subject Page
Other reactive compounds 609
May affect DNA :.. 609
ACRYLONITRILE
Other reactive compounds 609
May affect DNA 609
Organism, dose, effect 639
Products, producers 645
Application 645
Chemical name, formula 645
Physical properties 645
Product form 645
Oral toxicity LD-SO 645
Major end uses 645
ACTIDONE
See CYCLOHEXIMIDE
ADENINE
Chromosome abci-at ions 591
Mutagenic effect 591
Mutagenic DNA alterations 605
DNA bases 60S
ADEMNE ARABINOSIDE
Chromosome aberrations in
higher plants 583
ADENINE XYLOSIDE
Chromosome abet rations in
higher plants 583
AFLATOXIN
Carcinogen 251
AGRIMYC1N
Antibiotics used as fungicides 66
Bactcricide 66
Use rate 66
Ancillary methods, bacterial 572
Methods, based on resistance 573
ALANAP
See NAPTALAM
-------
CHEMICAL SUBSTANCE IN )EX
ALAR
Growth retatdants
UK in agriculture
Replacement of, by new
soil insecticides
Worldwide usage, 1966
Rice crops
Use to control pests
Cereal crops
Use to control pests
Sugar beet crops
Use to control pests
Sugarcane crops
Use to control pests
74
74
ALCOHOL
Use as wash for parathion,
decontamination of
human skin 400
Behavioral effects of solvents 417
Solvents in air, resembling
alcohol effects 417
Influence upon behavior 419
ALDRIN
Persistence 9
Environmental contamination 9
Needed knowledge of sample
composition, purity 11
Decrease usage over next 2 years 26
Blood level, rncssurc of exposure 33
Controlled human studies 35
Use in agriculture, crops 48
Uses 51
Sates 52
Use for teti.-.'te control S3
Use, foreign countr.c. SS
60
Chlorinated aryl hydrocarbons 63
Uses 63
84
85
85
86
86
88
88
89
89
Termi'es 90
Use to control pests 90
Use as soil insecticide 104
Control of com rootworm 104
Atmospheifc contamination 113
Concentration in lakes 119
Potable water supply 121
Standards, limits 122
Fate of, in rice puddles 124
Water concentrations 128
Examination of estuaries 129
Cucumbers grown on treated
soil residues in
Residues, in seed crops
Conversion in plant cells
Acceptable daily intake,
FAO-WHO
Effect on phytoplankton
Effect on crab larvae
Mortality of wild-life
Controlled human volunteer
studies
Occupational exposure,
blood levels
132
133
133
137
Dietary intake 138
Uptake by f bnts 144
Decrease usage o\ :r next 2 years 180
Deaths to wild-life, from
treated cereal seed dressing* 200
207
209
213
Blood level, measure of exposure 232
233
Actions to improve protection
of public health 239
No extension of present uses 239
268
Acute oral toxicity, LD-50 313
Acute dermal toxicity. LD-50 313
-------
CHEMICAL SUBSTANCE INDEX
U.S. pesticide production, annual
Occupational exposure
Occupational exposure, results
Occupationally related
skin conditions
U.S. pesticide production, 1966
HEOD, residue of aldrin
and dicldrin
Occupational exposure, results
Effects on conditioned
reflexes, cats
Polypeuropalhy, humans
Method of analysis, blood
Tumohgenicity testing, results
Registered for use on food crops
Enzyme induction studies
in progress
Effect of feeding, rats, on
effect of subsequent
parathion poisoning
Effect on tissue storage
of DDT
Blood levels, occupational
exposure
Effect on tissue storage
Metabolism of
May affect DNA
Use in agriculture
Insecticide
ALLETHRIN
Botanicals, insecticides
Synthetic "pyrethrin"
Formulation as dusts, sprays
and aerosols
Formulation with syrergists
Toxicity to mammals
Use around livestock
Use around homes
315
349
351
366
382
386
409
409
417
448
470
470
520
ALLYL ALCOHOL
Other reactive compounds
May affect DNA
ALPHA-BHC
Sec after BHC
AMIBEN
Benzoic acid herbicides
Persistence in soil
Toxicity to mammals
Use in agriculture
Use rates
U.S. sales
Herbicides, preemergence
Widely used in agriculture
AMINOCARE
See MATACIL
6-AMINO-NICOTINAMIDE
Testing for increase anomalies
Testing for increase anomalies
2-AM1NOPURINE
Mutations in higher plants
DNA alterations
609
609
68
68
68
68
68
610
610
610
669
672
584
605
524
528
538
539
559
609
610
610
62
62
62
62
62
62
62
AMINOPTERIN
Mutations, chromosome aberrations
in higher plants 583
4-AMINOPYRIDINE
Use in bird control 73
AMITROL
Needed knowledge of sample
composition, purity 11
Heterocyclic nitrogen derivatives 69
Herbicides 69
Use in agriculture 69
Toxicity to mammals 69
Use rate 69
Persistence in soil 69
Mode of action 604
Inhibitor of potphyrin,
chlorophyll synthesis 604
No significant increase of
anomalies, as tested 674
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CHEMICAL SUBSTANCE INDEX
ANISYLACETONE
Synthetic insect ^ttractar.*
Use in controlling fruit
and melon (lies
ANTHRAQUINONE
I'se for bird control
Inhibition of DNA synthesis,
possibly
ANTIMYCIN
Antin.ycin, use as fish toxicant
Antibiotic, synthesized by fungi
Toxicity to invertebrates
Toxicity to fish
Degradation rate in water
ANTU
Rodenticides, selectivity
for rats
Use for Norway rat control
Judged not positive,
tumorigenicity study
Registered but not for use
on food crops
APHOLATE
Ethyleneimincs
Compounds known to affect DNA
AQLAL1N
See ACROLEIN
ARAMITE
Needed knowledge of sample
composition, purity
Judged positive, tumor induction
Registered for use on food crops
Tumor incidence, raring
Sulphates
Known to affect DNA
ARASAN
SecTHIRAM
ARSENIC
Salts of, persistence in soil
Salts of, inorganic rodcnticides
Residues in food samples
Daily intake
75
75
73
609
11
13
213
*> 1 1
21 y
213
213
•71
12.
72
475
475
606
606
11
470
470
489
606
606
45
71
137
137
Use in orchards
Persistence
Effects of, on plants
Use, domestic
Accidents, by industry.
by occupation
Poisonings, humans
Compounds use as plant growth
regulators, toxicity
Sodium KI senile-containing
herbicide, accidents, human
Chronic poisoning, phnses
Dermatitis
Occupational^ related
skin conditions
Urine, indicator of exposure
Poisoning, treatment of
ARSENIC SULFIDE
Inorganic rodentictde*
ARSENIC TRIOXIDE
Inorganic rodcnticides
ATRATRONE
Products, producers
Application
Chemical name, formula
Physical properties
Oral toxicity, LD-50
Major end-uses
ATRAZINE
Heterocyclic nitrogen derivatives
Herbicides
Use in agriculture
Toxicity to mammals
Use rate
Persistence in soil
Persistence
Use in agriculture
Urine, indicator of exposure
Tumorigenicity testing
Registered for use on food crops
145
145
145
147
154
158
205
362
362
365
366
448
451
72
72
645
645
645
645
645
645
69
69
69
69
69
69
104
104
448
475
475
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CHEMICAL SUBSTANCE INDEX
Tumorigenicity testing, rating 490
Pesticides mutations in bailey 584
Picemcrg :ncc herbicide 610
Use 610
Herbicide 610
Use in agriculture 610
Organism tested, dose, effect 639
ATROPINE
Treatment for organophosphorus
compounds 412
Atiopine, ovcrtrcatment
of poisoning 416
Antidote in humans, animals 426
Treatment in pesticide poisonings 450
Mechanism of action *S2
Antagonist in pesticide poisoning 452
Treatment in pesticide poisoning • -
Treatment of carbamate
poisoning in mice 454
Antidote for effects in
pesticide poisoning 534
Radiation, organophosphate,
exposure to 534
AVADEX
Needed knowledge of sample
composition, purity 11
Carbamates 70
Prccmergent herbicides 70
Persistence in soil 70
Toxicity to humans 70
Toxicity to warm-blooded animals 70
Judged positive,
tumor induction 470
Registered but not for use
on food crops 470
Tumor incidence, rating 489
Carbamatcs 491
Tumorigcnic activity, rating 491
AVITROL
See 4-AMINOPYRIDINE
AZASERINE
Chromosome aberrations 591
Mutagenic effects 591
AZINPHOSMETHYL
See GUTHION
AZOBENZENE
Tumor incidence, priority
for testing 473
Registered but not for use
on food crops 473
AZODRIN
Grasshopper control 92
Poor or lack of
grasshopper control 92
BAL
dictating agent for heavy
metal poisoiur g 451
Mcchan ism of action 451
Effectiveness in arsenic
poisoning 451
Effectiveness in mercury
poisoning 451
Effectiveness in lead poisonm? 451
BALAN
Dinitroaniline herbicides 70
Preemcrgcnt herbicides 70
Use in Held and crop
weed control 70
Use rates 70
Persistence 70
Toxicity to humans 70
Toxicity to warm-blooded animals 70
BANOL
Low protein diets, rats 532
Toxicity 532
Anticholinesterase insecticide 532
BANVEL D
See DICAMBA
BARBAN
SeeCARBYNE
BARIUM CARBONATE
Inorganic rodcnticides 72
Use rates 72
BARTHR1N
Botanical insecticide 63
Ester hydrolysis, oral
administration 547
Metabolism in rats, rabbits 547
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CHEMICAL SUBSTANCE INDEX
BAYCON
Carbain.'te insecticide 53
Resi;!vtcc to other pesticides S3
Res)Stai<--e '.n termites S3
Carbamatts 65
Mcxle of action 65
Major use 65
Use rate 65
Restricted use, for cockroaches
and other pests 65
Insecticides for household use 151
Use in controlling chlorinated
hydrocarbon resistant
cockroaches • 151
Toxicity symptoms in !iumans 348
Duration of action 348
Poisoning by carbamates 348
Reversible cholinesterase
inhibition 348
Useof2-PAM 348
t-'ield tests in Nygeria and Iran 361
Poisoning of humans 361
Clinical symptoms 361
Ophthalmic effects, topical 367
Effects or fibers, residents 369
Signs and syi.jp. •• it» 369
Experimental carbamale pesticide,
related to Baygon. effect
in rats 410
Effects on sprayers, residents 417
Effects on cholinesterase 417
Effects from prior spraying 417
Urine, indicator of exposure 448
Metabolism in housefUes.
effect of MDP compounds S5S
Chemical structure 5S7
Detoxification product 558
MDP compounds, synergixts SS9
BAYLUSCIDE
Use in snail control 72
Use in lamprey control 72
BAYTEX
See FENTHiON
BF.NEFIN
SeeBALAN
BENLATE
Converted to epoxide,
found in tady fat 609
May affect UNA 60?
Base analog CD9
BENS*.-IDE
See BETASAN
BENZAC
Benzoic acid compound 68
Herbicides 63
Persistence in soil 68
Toxicity to mammals 68
Use in agriculture 68
Use rates 68
BENZENE HEXACHLORIDE
SeeBHC
3,4-BENZPYRENE
Sesamin coctrcinogenic
. with 3,4-benzpyrene 543
Administration with MDP
synergist, liver damage S *4
F.ihancemem of toxicity with
otlier chemicals 546
BETASAN
Amide derivatives 70
Use as herbicides 70
Us; in agriculture 70
Use in home and garden products 70
Preemergent herbicides 70
Persistence in soil 70
Use rates 70
Toxicity . 70
N6-BENZYLADENINE
Cytokinins 74
Uses 74
Use rate 74
N6-BENZYL-9-TETRA-
HYDROPYRANADENINE
Cytokinins 74
Uses 74
Use rate 74
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CHEMICAL SUBSTANCE tt'DEX
BHC
Persistence, contamination
of environment 9
Insccticidal properties
recognized, 1940 45
Chlorinated aryl hydrocarbons 63
Use in agriculture 63
Use on world crops 84
Use on fruit crops
in foreign countries 84
Rice crops 85
Cereal crops 85
Use of BHC to control pests 85
Vegetable crops 87
Use of BHC to control pests 87
Potato crops 87
Limited use of BHC 87
Sugar beets 88
Use of BHC to control pests 88
Sugarcane 89
Use of BHC to control pests 89
Tobacco 89
Use of BHC to control pests 89
Oilseeds 90
Use of BHC to control pests 90
Locusts, control of with BHC 90
Grasshopper control
Losses of cattle products due to
grasshopper infestations
91
91
Drift from aerial spraying 108
Efficiency of mode of application 1C'9
Atmospheric contamination studies 114
Pesticides in rain water,
alpha BHC
116
Removal of, from water treatment 123
Concentrations in treated
and untreated water 123
Foods of animal origin 138
Source of BHC intake in diet 138
Residue retention in cow's milk 140
Actions to improve protection
or public health 239
No extension of present
uivsofBHC 239
Residues in human adipose tissue 269
Further information on kinetics
of beta BHC in mail, animals
desirable 269
Human pesticide residues 320
BHC concentrations,
negroes vs whites 322
Levels in Great Britain 328
Morbidity effects of
cccupational exposure 347
U.S. ptsticide production. I966 382
S"nagc of beta BHC by females
vs males
Effect of fat diet, effect on
toxkity. storage
Use in household formulations
Human adipose residues
429
Concentration of, in human milk
relationship to other chemicals 449
Ingcstion of flour
contaminated with BHC 450
Toxkity. effects from 450
Residues 525
Twecn 20, effect on tissue levels
ofbeta-BHC.rats 526
532
Concentration in tissues, humans 538
Household use of pesticide* 538
611
alpha-BHC
The water route 116
Rainwater, containing alpha BHC 116
Concentrations in rainwater 116
331
beta-BHC
Residues in human adipose tissue 269
Desirability of additional
information on kinetics 269
-------
CHEMICAL SUBSTANCE INDEX
liu;nan adij'-ose re jdues 331
Storage of. in females vs mates 429
Effect of increased tat in
diet on storage 526
Twcen 20, effect on tissue levels S26
GAMMA BIIC
See LINDANE
BIDRIN
Organophosphorous compounds 64
Al'phatic derivatives 64
t«e rates 64
Acute oral toxkity. LD-SO 312
Acute dermal toxicity, LD-SO 312
Reports of occupationally
related skin conditions 366
Accidental exposure, human 367
Orpanophosphorous compounds 367
Effects on eye 367
Metabolism in houscflics 555
Effect of M DP compounds on 555
Organophosphates 665
Qtolincstcrasc inhibiting
insecticides 665
Teratogenic in chick embryos 665
BINAPACRYL
See MOROC1DE
BIPHENYL
Tumor incidence, testing 473
Registered for use on food crops 473
Piperonyl butoxide. inducer of
biphenyl metabolism 554
Effects of pipcronyl butoxide
on hydroxylation of biph^nyl
in liver microsomes of mice 554
BIS1SOPROPYLAMIDO
FLUOROPHOSPHATE
SeeMIPAFOX
BISMUTH
DITHiOCARBAMATE
Tumorigenicily testing, rating 491
BOMBYKOL
Insect attra rtants ?$
BORDEAUX MIXTURE
Inorganic fungicides 66
Use in agriculture 66
Use rates 66
BOTRAN
SccDICIIl.ORAN
BROMAC1L
Herbicides, mi«cellaneous
category 70
Base analogs 609
Converted into epoxides,
in body fat 609
May affect DNA 609
BROMINE
Fumigants containing bromine 198
Bromide residue in soil 198
Bromide residues in milk 198
Atoms on Frcons 545
Chromosome aberrations in
higher plants 583
5-BROMODEOXYCYTIDINE
Mutations in higher plants 583
5-BROMODEOXYl'RIDINE
Mutations in higher plants 583
Chromosome aberrations 591
Muu^-mc effects 591
BROMOMETHANE
Bromides and chlorides 606
Affect DNA 606
Mutations, chromosome alterations 606
BROMOPROPANF.
Bromides and chlorides 606
Affsct DNA 606
Mutations, chromosome alterations 606
5-BROMOURACIl.
DNA alterations
BROMOXYNIL
See BUCTRIL
BUCTRIL
Nitrite herbicides
Toxicity to mammals
Us« rates
605
70
70
70
-------
CHEMICAL SUBSTANCE INDEX
BUdR
Reasttnce to 9UdR 588
Treatment of Chinese hamster
cells with BUdR S88
BUTACIDE
Tumor testing 475
Registered Tor use on Toed crops 475
Cbripare with piperonyl buloxide 475
Tumorigenicity testing, rating 492
Piperonyl buloxide tested
as Butacide 492
Development of lymphomas 492
BUTOXY PROPYLENE
GLYCOL
Insect repellents 75
3UTYLATE
See SUTAN
BUTYLATED
HYDROXYANiSOLE
I'ood Additive 583
Chromosome aberration in
higher plants 583
BUTYIATED HYDROXY
TOLUENE
Food additive 583
Chromosome aberrations in
higher plants 583
N-BUTYL METHANE
SULIONATE
Mutations in higher plants 584
Mutations 585
BUTYLSORBATE
Insect attraction 75
BUX-TEN
Carbamate insecticides 65
Mode of action 65
Use in agriculture 65
Use rates 65
Carbamates 607
May affect DNA 607
VS. safes, use in agriculture 610
Insecticide 610
CACODYLIC ADD
Metal-organic compounds 68
Used to control crabgnss.
weeds 68
Tumorigenicity testing, rating 475
Registered but not for use
on food crops 475
CADMIUM CHM3RIDE
Inorganic fungicides 66
Use in agriculture 66
Use rates 66
CADMIUM. DIETHYL
DrrmOCARBAMATE
Tumorigcnicity testing, rating 491
CAFFEINE
Chromosome aberrations in
higher p'ants 584
Chroniosnrrc aberrations 591
Mutagenic effects 591
Study of synergistk effect
with X-fjys 598
Results of dominant lethal
mutation testing 598
CALCIUM ARSENATE
Inorganic insecticides 62
Use restricted, toxicity,
persistence 62
Inorganic herbicides 68
Use rales 68
Possible inclusion in slug
and snail baits 73
U.S. pesticide production, 1966 382
CALCIUM CYANlDt
Inorganic rodenticides 72
Use rates 72
CALCIUM DISODIUM
EDETATE
SeeEDTA
CAPTAN
Needed knowledge of sample
composition, purity 11
Chlorine-containing fungicide 67
Uses 67
Use rate 67
VS. Pesticide production, annual 315
Occupational dermatitis 36S
Occupational exposure,
allergic dermatitis 399
-------
CHEMICAL SUBSTANCE INDEX
Mutagenic effects
438
Spsaying of farm animals.
Tumorigenicity testing, results
Registered for use on food crops
Tumorigenicity testing, results
Diet, effect on acute toxkity
Half -life in serum
Mutagenic hazard
Fungicide
Use in agriculture
Organism tested, dose, effect
Products, producers
Application
U.S. patent numbers
Chemical names, structure
Physical properties
Oral toxicity. LD-50
Major end uses
Tcratogenk
Teratosenic in chicken embryos
Production of abnormal fetuses
Testing for increase anomalies
CAPTAX
See 2-MERCAPTO-
BENZOTHIAZOLE
CARBARYL
Needed knowledge of sample
composition, purity
New pesticides, rarbamatei
Uses, insect control
Non-persistence
Grasshopper control
Non-persistent pesticides
mm
Usage
Persistence, in comparison with
malathion, parathion
Residues on cabbage, eggplants
Residues
Calculated daily intake
Acceptable daily intake,
FAO-WHO
473
473
490
532
603
603
610
610
639
645
645
645
645
645
645
MS
658
664
666
673
11
59
59
59
92
104
1 /U
IIM
104
134
136
136
137
residues
Home canning, removal of residue
Susceptibility of bees to
Effect on crab larvae
Morbidity effects of
occupational exposure
Exposure, symptoms, usage
Occupational exposure, poisonings
Penetration of
Sample skin matrix
Effect on self-protective
responses, rats
Effect on rats, adult vs weanling
Urino, indicator of exposure
Treatment of poisoning
Tumorigenicity testing, results
Registered for use on food crops
Tumorigenicity testing, rating
Synergism with MDP compounds
Mutations in barley
May affect DNA
Use in agriculture
Insecticide
Organism tested, dose, effect
Products, producers
Application
U.S. patent number
Chemical name, formula
Physical properties
Product foims
Oral toxicity. LD-50
Major end uses
Teratogenidty testing, results
Teratogenic studies, results
139
141
208
209
345
348
361
403
405
410
427
448
452
469
469
491
542
584
607
610
610
639
646
646
646
646
646
646
646
646
658
664
10
-------
CHEMICAL SUBSTANCE INDEX
Increase in abnormal fetuses 666
Cystic kidneys, with
pipcronyl butoxide 666
Testing for increase anomalies 673
Testing for increase anomalies.
with nicotinamide 674
CARBOFURAN
See FURADAN
CARBON DISULFIDE
Use early as pesticide 45
CARBON TETRACHLORIDE
Eff.-cl on methoxychlor toxkity 430
Liver damage, rats 430
Effect on EEC patterns 4SI
Chlorinated solvent* 451
CARBOPHENOTH1ON
Set- TRITHION
CARBYNE
rarbamatcs 70
Pro-emergent herbindrj 70
Use ntes 70
Toxicity to humans 70
Toxicity to warm-blooded animals 70
Carbamates and thiocarbamates 607
May affect CNA 607
CARZOL
Carbamates and thtocaibamatcs 607
May affect DNA 607
CASORON
Nitrile herbkides 70
Use in weed control 70
Persistence in soil 70
Use rates 70
CCC
Tumor incidence, priority
for testing 473
Registered but not for use
on food crops 473
Tumorigenkity testing, rating 489
CDAA
Amide derivatives 70
Use as herbicides 70
Persistence in soil 70
Use rates 70
Dermal toxkity 70
Toxkity 70
Carbamates and thiocarbamates 607
May affect DNA 607
U.S. sales, use in agriculture 610
Herbicide 610
CDEC
See VEGEDEX
CEEPRYN
Chromosome aberrations in
higher plants 583
CERESAN M
See ETHYLMERCURY
CHLORIDE
CERTRCL
Sec IONXYNIL
CHARCOAL
Use of charcoal dinted runways
in studying DDT effect on
locomotion 409
Use in poisoning cases 450
Treatment of cows, with
phenobarbital, effect on
dicldrin levels 529
CHIPCOTE 25
Organic mercury compounds 66
Uses 66
Use ntes 66
CHLONITRAI.ID
See BAYLUSCIDE
CHLORANIL
Chlorine-containing fungicides 67
Use rate 67
Uses , 67
Tumorigcnicity testing, priority
for testing 473
Registered but not for use on
Tood crops 473
Tumorigenicity testing, rating 490
CHLORDANE
Persistence 9
Environmental contamination 9
Persistence 26
Decrease usage over next 2 years 26
11
-------
CHEMICAL SUBSTANCE INDEX
Replacement by diazinon
Rcastcncc to
Use in termite control
Usage, foreign countries
Chlorinated aryl hydrocarbons
Uses
Worldwide usage
Persistence
Air contamination, analysis or
Ground waters, analysis of
Potable water supply
Standards, limits
Usage, domestic
Use against ants, cockroaches
Insecticides for household use
Accidents, by industry, by
occupation
Persistence
Decrease usage over next 2 years
Effect on phyioplanktcn
Acute oral toxicity. LD-50
Acute dermal toxicity, LD-50
U.S. pesticide production, annual
Effect on excitability of
nervous system
Occupational^ related skin
conditions
/
Henutotogical disorders
Occupational exposure, results
Accidental ingestion of
Blood dyscnsias
Liver changes, rats
Enzyme induction
Enzyme induction, measurements
in progress
53
53
53
55
63
63
84
104
113
117
121
122
147
151
151
154
ISO
180
207
313
313
315
360
366
372
312
312
389
435
S18
520
Effect of feeding, rats, on
subsequent parathion poisoning
Diet, effect on acute toxicity
Use in agriculture
Insecticide
Use in household formulations
Embryotoxicity in rats, dogs
GAMMA CHLORDANE
Enzyne induction by other
chlorinated hydrocarbons, rats
CHLORIENSON
See C VEX
CHLOROBENZILATE
Needed knowledge of sample
composition, purity
Compounds related to DDT
Use rates
Use as insecticide
Use as miticide
Acute oral toxicity, LD-50
Acute dermal toxicity
Tumorigcnicity testing, results
Registered for use on food crops
Compounds related to DDT,
structurally
Tumorigcnicity testing, rating
2-CHLORCM.6-bis
(ETHYLAMINO)-S-
TRIAZINE
See SIMAZ1NE
2-CHLOR >N-DIALLYL
ACET/.MIDE
Allergic contact sensitization to
Occupational exposure, humans
2-CHLORO-2-DIETHYL-
CARBAMOYL-1-METHYL
VINYL DIMETHYL
PHOSPHATE
See PHOSPHAMIDON
CHLORODIMETHYLAMINE
Nitrogen •nustards
Mutation* in Neurospora
524
532
610
610
611
664
S2C
11
63
63
63
63
313
313
470
470
489
489
399
399
S85
585
12
-------
CHEMICAL SUBSTANCE INDEX
BIS (2-CHLOROETHYL)
ETHER
Needed knowledge of sample
composition, purity 11
Judged positive tumor induction 470
Registered but not for use
on food crops 470
Tumor incidence, rating 489
CHLOROETHYL METHANE
SULFONATE
Mutations in higher plants 584
Mutations in Ncurospora 585
2-(CHLOSOETHYL)
TRTMETHYLAMMONIUM
CHLORIDE
See CCC
CHLOROFORM
Use as solvent for extraction 174
Organism tested, dose, effect 639
Products, producers 646
Applications 646
Chemic al name, formula 646
Physical properties 646
Major end uses 646
CHLORO IPC
Sec CHLORPROPHAM
CHLOROPHENOTKANE
See DDT
3-(p-CHLOROPHENYL)-
l.I-DIMETHYLUREA
Sec MONURON
2-CHLOROPHENYLPHENATE
Chlorinated phenols 370
Nasal, bronchial irritation 370
CHLORO-2 PHENYLPHENOL
Conjunctivitis in apple sorters 368
Dermatitis, humans 368
CHLOROP1CRIN
Halogcnated hydrocarbon
, nematocides 71
Dowfume MC-33 (mixture of
methyl dibromide plus
chloropicrin) 71
Chlorinated aliphalics 367
Eye irritation 367
Chlorinated aliphatics 369
Respiratory irritation 370
Use as nematocide 370
6-CHLOROPIPERONYL
CHRYSANTHEMUMATE
See BARTHR1N
CHLOROPROPYLATE
Organochlorincs 63
Compounds related to DDT 63
Use rates as insecticides 63
Use rates as miticidcs 63
2-CHLOROTRIETHYL AMINE
Mutations in higher plants 583
Mutations 585
CHLOROXURON
Substituted urea., 69
Herbicides 69
Persistence in soil 69
Use rates 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
Ureas 608
May affect DNA 608
CHLORPROMAZINE
Effect on cortical activating
system 418
Effect on attention test 418
Induction of microsomal enzymes 528
CHLORPROPHAM
Carbamates 69
Use in agriculture 69
Use rates 69
Persistence in soil 70
Toxicity to humans 70
Toxicity to warm-blooded animals 70
Judged not positive, tumor
inducuon 469
Registered for use on food crops 469
Tumorigenicity testing, rating 490
Tumorigenicity testing, rating 491
13
-------
CHEMICAL SUBSIANCfi INDEX
Products, producers 646
Application 646
Chemical name, structure 646
Physical properties 646
Product forms 646
Oral toxicity, LD-50 646
Major end uses 646
No significant increase in
anomalies 674
CHLORTHION
Acute oral toxicity. LD-50 312
Acute dermal toxicity, LD-50 312
Aerosolization of, cutaneous
contamination 445
Inhibition of hepatic metabolism
ofdcsoxycorticosterone 533
CIODRIN
New pesticides 59
Use in control of flics 59
Organophosphatcs, phcnyl
derivatives 64
Use rates 64
Urine, indicator of exposure 448
CIPC
See CHLORPROPHAM
CLOBBER
Sec CYPROMID
CLOROX
Inorganic fungicides 66
Use in agriculture 66
Use rates 66
COAL TAR
Fungicides 202
Wood preservatives 202
COLCHICINE
Mutations in higher plants 583
Pretreatment, cell studies 593
Effect on spindle formation 604
COMPOUND 1080
Development by U.S. Fish and
Wildlife Service 45
Use as rodcnticide 45
Fluoride rodenticides 72
Toxicity to warm-blooded animals 72
Properties 72
Rodenticides 214
Toxicity to man 214
Toxicity to domestic animals 214
Production of ventricular
fibrillation 371
Production of cardiac arrest 371
Death from 371
CONTRATH1ON
Antagonize muscle paralysis of
cholincsterase inhibitors 453
COPPER
Salts of, use as pesticides 45
Inorganic fungicides 66
Metal organic fungicides 66
Uses 66
Use rates 66
Contained in fungicides 202
Sulfatc, U.S. pesticide
production, annual 315
Sulfatc, U.S. pesticide
pioduction, 1966 382
Poisoning, treatment of 451
8-hydroxyquinolinc, tumorigcn-
fcity testing, results 475
COPPER DfTHIOCARBAMATE
Tumorigenicity testing, rating 491
COPPER 8-
HYDROXYQUINOLINE
Tumorigenicity testing, priority
testing 475
Registered but not for use on
food crops 475
COPPER NAPHTHENATE
Metal organic fungicides 66
Used in treatment of handling,
harvesting and storage
equipment 66
Use rites 66
Used to prevent rot and mildew 66
14
-------
CHEMICAL SUBSTANCE INDEX
COPPER OXID3
Inorganic fungicides 66
Uses 66
Use rates 66
COPPER OXIr'ATE
Metal organic fungicides 66
Uses 66
Use rates 66
COPPER SULFATE
Inorganic fungicides 66
Uses 66
Use rates 66
U.S. pesticide production, annual 315
U.S. pesticide production. 1966 382
COPPER ZINCCHROMATE
Inorganic fungicides 66
Uses 66
Use rates 66
CORAL
Organophosphates 64
Use in agriculture 64
Use rates 64
Acute oral toxicity, LD-50 31 ?.
Acute derm.J toxicity. LD-50 312
COTORAN
See FLUOMETURON
COUMAFURYI.
See FUMARIN
COUMAPHENE
See WARFARIN
COUMAPHOS
SeeCO-RAL
COUMARIN /
Food Additive 583
Chromosome aberrations in
higher plants 583
CREOSOTE
Pesticides before 1945 44
Introduction as insecticide
in 18th century 44
Miscellaneous insecticides 65
Used to prevent termite damage 65
Miscellaneous fungicides 67
Uses 67
Use rates 67
Wood preservative 202
Toxicity to non-target organisms 203
CRYOLITE
So: SODIUM
FLUOALUMINATE
CUELURE
Synthetic insect attractants 75
Use to control flies 75
CYANAMIDE
Tumorigenicity testing, priority
for testing 473
Registered but not for use on
food crops 473
CYANIDE
Hydrogen cyanide, development of
resistence to 45
Fumigants, hydrogen cyanide 65
Use rates 65
Inorganic rodcntirides 71
Calcium cyanide 72
Sodium fluorosilicate plus
zinc cyanide 72
Toxicity €05
Mutagenic study 60S
Hydrogen cyanide, products,
producers 649
Application 649
Chemical name, formula 649
Physical properties 649
Oral toxicity, LD-50 649
Major end uses 649
CYCASIN
Plant toxin 594
Formation of muUfenic
metabolic products from 594
CYCLOHEXIM1DE
Use rates 66
Use as fungicides 66
CYCOCEL
Growth retardants 74
CYGON
See DMETHOATE
CYOLANE
Organophosphates 608
May affect DNA 608
IS
-------
CHEMICAL SUBSTANCE IKDEX
CYPREX
See DOOINE
CYPROMID
Amide derivatives
Preemcrgent herbicides
Persistence in soil
Use rates
Toxicity
CYTOSINE ARABINOSIDE
Chromosome aberrations in
higher plants
Chromosome aberrations in
mammalian cells, tissue culture
•TYTROL
Mutagenic in plants
?.4-D
Needed knowledge of sample
composition, purity
Introduction in 1930's
Phenoxy herbicides
Uses
Toxic
-------
CHEMICAL SUBSTANCE INDEX
2.4-D BUTOXY ETHANCL
ESTER
Amount applied in reservoir areas 126
Herbicide 126
Toxicity to aquatic fauna 126
Toxicity to mosquito larvae 126
Determination 10 months after
treatment with 2,4-D 126
2.4-D BUTYL ESTER
Tumorigcnicity testing,
judged not positive 475
Registered for use on food crops 475
Testing for increase anomalies 673
2.4- D ETHYL £STER
Testing for increase anomalies 673
2.4-D ISOOCTYL ESTER
Tumorigcnicity testing, results 475
Registered for use on food crops 475
Production ov* abnormal fetuses
in litters 666
Testing for increase anomalies 673
2,4-D ISOPROPYL ESTER
Tumorigenicity testing, results 474
Registered for use on food crops 474
Production of abnormal fetuses
in liners 666
Testing for increase anomalies 673
2,4-D METHYL ESTER
Testing for increase anomalies 673
DACONIL 2787
Chlorine-containing fungicides 67
Uses 67
Use rates 67
DACTHAL
Phthalic acid herbicides 68
Preemergence compounds 68
Persistence in soil 68
Toxicity to mammals 68
Use rates 68
DALAPON
SeeDOWPON
DCNA
See DICHLORAN
DCPA
See DACTHAL
DCU
Ureas 608
May affect DNA 608
DDA
Concentration in urine, excreta,
monkeys, human.- 268
Relation to DDT intke 263
Concentration of DDA in excreta.
monkey, vs daily dose DDT 289
p,p'-DDA in urne, humans, vs
time of treatment with
p,p'-DDT 290
Concentration of p.p'-DDA in
urine, humans, vs
concentration of p,p'-DDT
in body fat 291
Ingcstion of DDT, excretion of
metabolite, humans, effect 298
Urinary excretion, humans 299
Principal metabolite of DDT 388
Concentration in urine,
indicator of exposure 388
Excretion of in urine,
monkeys, humans 427
p.p'-DDA
Concentration in urine, humans,
treatment with p,p'-DDT 290
Concentration in urine, humans,
vs concentration of p,p'-DDT
in fat 291
DDD
Uses, restricted to use for
which no alternative available 8
Concentration in lakes 119
Applied to lake for gnat control 126
Water concentrations 128
Examination of estuaries 129
Ren- ues in cow's milk 140
17
-------
CHEMICAL SUBSTANCE INDEX
Persistent chlorinated
hydrocarbons 180
Decrease usage over next 2 years 180
Nerve poison in insects 189
Effect on reproduction in birds 212
Studies in volunteers 296
Experimental oral exposure 300
Acute oral toxicity. LD-50 313
Concentration in human milk 449
Eliminate use in food production 472
Effect on dieldrin storage S27
o.o'-DDD
Tumorigenicity testing, rating 489
o,p'-DDD
Attophy of adrenals in dogs 300
Effect on adrenals in man 301
Signs and symptoms, humans 301
Taatogenicity testing, rating 489
Testing for increase anomalies 673
p,p'-DDD
Residues of, human adipose tissue 269
Teratogenicity testing, results 473
Registered for use on food crops 473
Residues in human tissues S2S
Testing for increase anomalies 674
DDE
Metabolite of DDT 9
Distribution in environment 9
In blood, long term exposure 33
Atmospheric contamination 113
Transport by storms 113
Concentration in lakes 119
Water concentrations 128
Examination of estuaries 129
Dietary intake. FAO-WHO 137
Residues ii. cow's milk 140
Blood leveU, hunrms 148
Action as nerve poison in insects 189
Effect in buds, on reproduction 189
Contained in fish 209
Effect on reproduction in birds 212
In blood, long term exposure 232
In human tissues 245
Paper chromatography of 257
Blood and adipose residues.
human.-. 321
Occupational differences,
residue; in 322
Age relationship, residues 323
Residues, Iskimo adipose tissues 326
Concentration in home
environments 327
Residues, levels and disease 328
In blood, c'tildren 336
In adipose, humans, by age
and race 337
Storage, in comparison with
DDT. volunteers 349
Levels, association with age 357 ~'
Annual intake 384
Dietary intake 385
In tissues, humans 386
Conversion of DDT to DDE
by man, rats 424
Conversion of DDT,
various rpecies 427
Influence of sex hormones
on storage, rats 428
Conversion of DDT in humans 429
18
-------
CHEMICAL SUBSTANCE INDEX
Storage of. r.ts, infestation
with Trichina 430
Blood levels of, effect on
patients taking phenobaibital
and dilar.tin 436
In blood, humans, occupational
groups, whites vs non-whites 449
Effect on dkldrin storage 527
Effect of aldrin administration,
dogs, humans 528
In blood, humans 529
In adipose tissues, humans,
exposure to household
pesticides 537
In adipose ussue,
occupational exposure 538
Converaor of DDT to DDE by
houseflys, effect of MDP
compounds en 559
Transplacental passage of
DDT and DDE, humans 675
pj'DDE
Residues of in human
adipose tissue 269
In adipose, humans 340
In adipose, humans 341
Residues, humans 525
DDMU
Effect on c'ieldrin storage 527
DDT
Eliminator of use of DDT within
two years, conditions 8
Distribution in man, animals,
environment 9
Use in developing nations 9
Persistence 9
Environmental contamination 12
Development of standards 12
DDT contamination lakes, rivers 13
In Coho salmon 13
Contained in foods 14
Effect of Delaney clause 14
Distribution in global
environment 19
Use in domestic pest
control programs 21
Use in malarial control
programs 21
Persistence 25
Effect on reproduction, survival
of nontarget species 25
Effect on egg shells in
ducks, falcons 25
Use reduction during next 2 years 26
In blood, relation to
recent exposure 33
Safety, acute intoxication 34
In general population, effects 34
Industrial exposure 35
Need for limit in blood 35
Human residues, donates 35
Enzyme induction, liver 36
Use in domestic pest
control programs 43
Use in malarial control programs 43
Insecticidal properties.
discovery of in 1939 44
Insecticidal properties,
Switzerland. 1939 45
Military use of. World War II 45
Use of, typhus epidemic 45
Use of after 1945 46
Resistance to 46
Exports in 1967 47
Usage in agriculture, survey 47
Usage of in agriculture. 1966 48
Production, exports 48
Usage 48
Uses 48
Production, exports 49
Use in malarial programs 49
Persistence 49
19
-------
CHEMICAL SUBSTANCE INDEX
" J'ety to nan
Banning of use in U.S.
Methoxychlor usag:,
comparison with DDT
Uses, commercial pest
control operators
Foreign, countries.
insecticide uses
Resistance in housefly,
1946, Sweden
Gypsy moth control, replacement
of DDT by Sevin (carbaryl)
Mosquito larvae control.
replacement of DDT by Abate
Most wide!;- un,^ organochlorine
Reduced incentives for industry
industry *o develop new
compound*
Cost per pound
Cost per pound, 1968
World crop usage of insecticides
Use on fruit, foreign countries
Rice crops
Use of DDT to control pests
Vegetables
Use of DDT to control pests
Potatoes
Use of DDT to control pests
Sugar beet
Use of DDT to control pests
Tobacco
Use of DDT to control pests
Oil seeds
Use of DDT to control pests
Yritow fever and malaria
Use against Aedcs Aegypti
Sleeping sickness
Use of DDT in foreign countries
River blindness
Persistent pesticides
Uses, exports
50
SO
51
54
55
59
60
60
63
79
79
80
S4
84
85
85
87
87
87
88
88
88
89
89
90
90
91
91
91
91
91
104
104
Drift after aerial spraying
Drift of spray and dust
fotirula Jons
Toxicity to budworm
Comparison with Zectran
Drift in storms
Atmospheric contamination
Daily intake, food, air
Water supplied, ground water
Levels in oysters, seasonal
changes
Levels in lakes
In Coho salmon
Fate in aquatic systems
Inhibition of marine
algal photosynthesis
Effect on phytoplankton
Mosquito control
Resistance
Water concentrations
Monitoring of estuaries
Shellfish shampling for
pesticides
Concentrations in river basins
Wheat, residues in
Residues, in diet
Dietary intake
Dietary intake, FAO-WHO
Foods of animal origin '
Sources of residue
Fed to cows, concentration
in milk
Residues in cow's milk
Removal of residues from
tomatoes by canning methods
Removal of residues from potatoes
Residue after storage
Domestic usage, pounds
108
109
111
111
113
113
114
117
118
119
119
120
121
121
127
127
128
129
129
129
133
135
136
137
138
138
• <• n
139
140
141
141
141
147
20
-------
CHEMICAL SUBSTANCE INDEX
Use of DDT in homes
Blood levels
148
148
Mothproofing chemicals ISO
Humin exposure, mothproofing ISO
Household use 1S1
Control of mice 1S1
Control of cockroaches 151
Exposure of workers 1S3
Residues in adipose tissue
vs general population 153
Accident1;, by industry, by
occupation
Syndrome in bird poisoning
1S4
Hazard from indoor house spraying
vs other applications 1SS
Persistence 179
Effect on reproduction, survival
of nontarget species 179
Effect on egg shells
ducks, falcons 179
Use reduced over next 2 years 180
Persistence 187
Concentration in food chain 187
Food web, residues of DDT 188
Effect on target, nontarget
organisms 189
Mechanism of action in insects 189
Use of, to save trees 195
Mode of death in insects 206
Effect on phytop!ankton 207
Effect on beneficial insects 207
Concentration by molluscs 208
Effect on crabs- 209
Effect on lake trout 209
Effect on issh reproduction 209
Effect on bird reproduction, in
companion with DDE 210
Mortality in fsh fry
and fingerlings 210
211
In fat of wild mammals 213
Composition of commercial DDT 213
Use of, in U.S. 221
In blood, relation to recent
exposure 232
Safety, acute intoxication 233
Limit in blood, need to establish 234
Residues in humans 234
Enzyme induction
235
Actions to improve protection
of public health 239
La filiation of uses essential for
public health purposes 239
Storage in tissues, humans 245
Effects in humans 246
Enzyme induction 246
Use, ease of identification 255
Presence in human adipose tissue 255
Gaps in knowledge regarding
DDT 255
Source of error in
analysis of DDT 257
Polychlorinated biphenyls (PCS)
in gas chromatographic analysis 257
Concentrations in tissues vs
level in diet 264
Duration of exposure vs
concentrations in tissues 265
Relationship between
concentrations in various
tissues 267
Concentration in tissues vs
time since exposure ceased 267
Storage in Rhesus monkeys 268
Organochlorines in human adipose 269
Metabolites in excreta 270
In body fat, comparison with
HEOD
272
Birds, effect of DDT treatment 212
Effects of DDE on reproduction 212
Results of studies, implications 273
Storage in rat tissues 27S
21
-------
CHEMICAL SUBSTANCE INDEX
Stooge in adipose tissues
Concentration in body fat vs
concentrations in diet
Concentration in fat, humans,
vs daily dose
Concentration in fat.
inale rats, vs diet
Concentration in fat, monkey,
with continuing exposure
Concentration in fat, monkey.
after exposure terminated
Concentration in fat, male rats,
during post-exposure period
Concentration in excreta,
monkey, vs daily dost
Studies in volunteers
Experimental respratory exposure 296
Experimental dermal exposure
Experimental OK! exposure
Properties of solutions of
Human exposure, oral, inhalation
Storage and excretion studies
Concentration in fat after
exposure terminated
Use, in selected jaundiced
prtients
Storage, dynamics of
Acute oral toxicity, LD-SO
Acute dermal toxicity. LD-SO
U.S. pesticide production
Human pesticide residues
Studies
Pathologies, residue of DDT
Adipose, blood levels of
Effect of personal variables
on adipose, blood levels
Sex differences, effect on DDT
Ethnic differences, effect
on DDT
276
277
278
281
282
286
287
289
296
296
296
297
?OQ
4,70
298
299
300
300
302
313
313
315
319
320
321
321
322
322
322
Age differences, effect on DDT
Socio-economic differences.
effect on DDT
Effect of drugs on metabolism of
Place \ viable effect on DDT
OccupationaUy exposed.
residues in
Time variable
Discussion of residue data
Dietary soirees
Non-dietary sources
Secular changes
Levels and disease
Use in treatment of
unconjugatcd bilirubinemia
Occupational exposure, plasma
levels
Effect of age on residues
in adipose
In blood, children
Concentration in adipose.
human, vj age, race
Concentration in adipose, humans.
in U.S. general population
Residues in general population
Morbidity effects of
occupational exposure
Occupational exposure
Concentration in fat of
occupationally exposed vs
general population
Human volunteers
Enzyme induction
Blood level limits
Occupational exposure
Enzyme induction
Effects on th - nervous system
Acute DDT poisoning
Search for chronic DDT
effects
Effects on skin
323
323
323
324
324
324
325
326
327
328
328
329
329
335
336
338
340
341
347
348
348
349
356
356
356
357
359
359
359
363
22
-------
CHEMICAL SUBSTANCE INDiJC
Occupationally related
skin conditions 366
Mixture of chemicals used for
treating furniture 367
Monocular retrobubular
neuritis, mixtures 367
Effects on cardiovascular system 370
Henutologic*l disorders 372
Effects on gastrointestinal tract 372
Residue in human milk 374
Ingestion of, by
breast-fed children 374
VS. pesticide production, 1966 382
Occupational exposure 383
General population exposure 384
Dietary intake 385
In body tissues 386
Storage in human fat 387
Me tabolite DDA in urine 388
Toxicity studies, rats 388
Human volunteers 390
Occupational exposure 391
Discussion on exposures 392
Exposure of popuh 'Ion 393
Clinical effects, exposures doses 393
Tissue levels, time trends 394
Percutaneous penetration,
route of excretion 402
In formulation Fekcma ES-30-9 405
Action in nervous system 408
Behavioral changes,
occupational exposure 409
Effect on locomotion, rats 409
Effects on nervous system 413
Effects of repeated exposures,
(Draymen, Baygon 416
Effects on liver, rodents 424
Acute effects on nervous system 425
Effects cf DDT poisoning 425
Effects on liver 425
Storage in fat 425
Goats, refractory to DDT
toxicity 426
Insects, mammals, differences in
susceptibility, absorption 426
Fed to rats 427
Fed to monkeys 427
Residurs, metabolites 427
Acute oral toxicity, sex effect 428
Storage, sex effect 428
Effect of sex hormones on
storage, toxicity 428
Sex dil Terences, storage, humans 429
Interaction of DDT and
trichinosis, rats 429
Toxicity, in carbor-tctrachloride
induced liver damage 430
Ingestion, human 430
Storage of in persons dying
of cancer, diseases 430
Mammals, fish, healthy, fat
effect on DDT poisoning 431
Effect of fat in diet on toxicity 431
Storage, excretion, rats,
starvation 431
Exaction of metabolites,
starvation 431
Effect on utilization
of Vitamin A 432
Effect of temperature on toxicity 432
Temperature, effect on
performance, rats 433
Histological changes,
livers, rats 434
Liver changes 434
Liver changes, monkeys 435
Effect on adrenal ccitex,
o,p'DDT isomer 435
Rate of storage, loss 435
Effect on liver enzyme
system, histology 436
23
-------
CHEMICAL SUBSTANCE INDEX
Effect on dieldrin storage 436
. reatment of unconjugated
nonhemolytic jaundice 437
Excretion in human milk 437
Estrogcnic effect, isomers 437
Effect on reproduction 437
Industrial, agricultural exposure 44S
Excretion of metabolite DDA,
in urine, humans, occupational
exposure, volunteers 447
In blood, whites vs nonwhites,
occupational groups 449
Health benefit; vs carcinogenicity
for man 463
Use, benefits 470
Carcinogenicity, discussion 471
Chronic human exposure 471
Benefits, uses 472
Effect of imposing zero tolerance 480
Chemicals structurally related
to DDT, carcinogenicity
raring 489
Correlation between exposure and
tiswc concentration 495
Enzyme induction 518
No-effect dietary level studied 519
Enzyme induction 519
Interaction with other chemicals 521
Enzyme induction, discussion 521
Persistent pesticides in tissues 525
Residues in consumer products 525
Surface active agents, effect
on oral toxicity, rats 526
Simultaneous administration with
dieldrin, effect on storage 527
Enzyme induction 527
Effect on metabolism of lindane 527
Effect on metabolism of DDT 527
Inhibitors of protein synthesis,
effect on DDT enzyme induction 528
Aldrin, effect on storage 528
Phcnobsrbital, use in acute
DDT poisoning 529
Effect of starvation 529
Effect of diet, low protein, rats 532
Factors determining storage 537
Residues, environmental exposure 538
Residues, occupational exposure 538
Residues time of exposure 538
Residues, after exposure
terminated
Bibliography
Organism tested, dose.
biological effect
Products, producer
Physical properties
Product forms
Oral toxicity. LD-50
Major end uses
Reproductive effects
539
Combined effects of DDT.
pyre thrum and piperonyl
butoxidc, rat liver 544
Chemical structure 556
Conversion to DDE, houseflics 559
Not suspected to produce
genetic mutations 606
Usage, insecticides 610
Use in agriculture 610
Use in household formulations 611
Organization of bibliography,
MEDLARS or manually
obtained 613
635
640
647
647
647
647
647
665
Study, human reproductive effects 674
Residues in human placentas 674
Study maternal blend levels vs
first trimester spontaneous
abortion 675
o.p'-DDT
Composition in commercial DDT 213
Estrogenic-iike effect in rats
and some birds 213
24
-------
CHEMICAL SUBSTANCE INDEX
Concentrations in humans 429
Atrophy of adrenal gland with
DDT 435
Concentrations of DDT in adrenal
gland in comparison with
other tissues 435
Effect on adrenal due to o,p'-DDT
in technical product 435
Estrogenic effects in rat 437
Residues in human tissues 525
p,p'-DDT
Needed knowledge of sample
composition, purity 11
Effect of isomers of DDT 213
Nonestiogcn-likc action in rats,
birds: unlike o.p'-DDT 213
Residues in human adipose tissue 269
Decline of residues after
exposure terminated 270
Concentration in fat, humans,
with continuing intake 283
Concentration in fat, steers,
after exposure terminated 288
Concentration of p,p'-DDA in urine,
humans, time of treatment with
p.p'-DDT 290
Concentration of p,p'-DDA in
urine, humans, vs concentration
ofp4>'-DDTinfat 291
Human*, concentration in fat 299
Excretion in urine of DDA 299
Plasma levels 300
Concentration in tissues,
males vs females 429
Non-estrogenic activity in rats 437
Estrogenic effects in-tats
Welch 437
Judged positive for tumor
indue Ion 470
Registered for use on food crops 470
Chlorine-containing compounds,
tutnorigenic 489
Tumorigenktty, rating 489
Residues, human tissues 525
DDVP
See DICHLORVOS
DEF
SeeFOLEX
DEFEROXAMISE
Iron Chdatii.g agent 451
DEHYDROACETIC ACID
Tumorigenkity testing,
priority for testing 475
Registered for use on food crops 475
DEI.NAV
Acute oral toxkity, Lb-50 312
Acute dermal toxkity, LD-50 312
DEMETON
Organophosphorus compounds.
aliphatic derivatives 64
Use rates 64
Controlled exposure, humans 296
Acute oral ioxkity, LD-50 312
Acute denral toxicity, LD-50 312
Occupational exposure,
health effects 345
Effects, exposure 364
Occupational!/ related
skin conditions 366
Handling, precautions for use 444
Organophosphates 608
May affect DNA ' 608
Methyl-demeton, systemic
insecticide 610
DEMOSAN
Chlorine-containing fungicides 67
Uses 67
Use rates 67
DEOXYADENOSINE
Chromosome aberrations
in higher plants 583
Chromosome aberrations 591
25
-------
CHEMICAL SUBSTANCE INDEX
67
67
67
67
608
608
608
413
418
DEXON
Miscellaneous fungicides
Used in agriculture
Uses
Use rale
May affect DNA
Mutagenicity, possible
Diazo compound
DFP
Reactivation of florid
psychotic attacks
Reactivation of psychosis
DIALLATE
See AVADEX
2.6-D1AMINOPURINE
Chromosome aberrations
in plants 591
Chromosome aberrations in
mammalian tissue culture cells S91
Mutagenic effects S91
D1AZINON
Replacement for chlordanc S3
Pest resistance to 53
Organo-phosphate 64
Use rate in agriculture 64
Organic phosphate 71
Use rate 71
Insecticides, nemaiocide 71
Grasshopper (Turura) control in
Argentina 91
Animals, precaution with 91
Household use 151
Cockroach control 151
Persistence IS I
Used with DOVP 1S1
Epidemics of poisoning by 310
' Acute oral toxicity. LD-50 312
Acute dermal toxicity. LD-50 312
DIBROM
See NALED
DIBROMOCHLOROPANE
SecNEMAGON
DIBUTYL SUCCINATE
Insect repellent 75
D.'CAMBA
Benzoic acid compound 68
Herbicide 68
Persistence in soil 68
Toxicity to mammals 68
Use in agriculture 68
Mutations in barley 584
Use in agriculture 610
Herbicide 610
Products, producers 647
Application 647
U.S. patent number 647
Chemical name, structure 647
Physical properties 647
Product forms 647
Oral toxicity. LD-SO 647
Major end uses 647
DiCHLOBENIL
SeeCASORON
DICHLONE
Chlorine containing fungicides 67
Use in agriculture 67
Use rate 67
Tumorigcnicity testing, results 475
Registered for use on food crops 475
Tumorigenicrty testing, rating 490
DICHLORAN
Chlorine containing fungicides 67
Use in agriculture 67
Use rates 67
2,6-DichJoro-4-nitroanilinc.
active ingredient in
formulation, Botran 473
Tumorigenicity testing 473
Tumorigenicity testing,
judged not positive 475
Registered for use on food crops 475
Compare with
2,6-dichloro-4-nitroaniline 475
Tumorigenicity testing, rating 490
Tumorigenicity testing, results 492
Amines and anilides 492
Mutations in barley 584
Organism tested, dose, effects 640
26
-------
CHEMICAL SUBSTANCE INDEX
Products, producers 647
Application 647
Chemical i.ame, structure 647
Physical properties 647
Product forms 647
Oral toxicity. LD-30 647
Major end uses 647
3.6-DICHLORO-O-ANISIC
ACID
See DICAMBA
p-DICHLOROBENZENE
See PARADICHLOROBENZENE
DICHLOROETHANE
Occupational exposure,
health effects 345
Effects on UNA. possible 606
2.6-DICHLOR&4-
NITROANIL1NE
Sec DICHLORAN
2.4-DICHLOKOPHENOXY-
ACETIC ACID
See 2,4-D
a-<2,4-DICHLOROPHENOXY)
PROPIONICACID
Tumorigenicity testing, results 474
Registered for use on food crops 474
DICHLOROPKOP
Phenoxy herbicides 68
Use 68
Systemic herbicide 68
Persistence 68
Toxicity to man 68
Toxicity to animals 68
Use rate 68
DICHLOROPROPANE
NcmatocMes, halogenated
hydrocarbon 71
Persistence, residual activity 71
Toxicity to humans 71
Used with dkhloropropenc 71
Toxicity to plants 71
Use rate 71
Pest control, nematocides 198
Application methods 198
Toxicity to non-target organisms 198
Fumigant 198
DICHLOROPROPENE
Nematocide, halogenated
hydrocarbon 71
Persistence 71
Residual activity 71
Toxicity to humans 71
Toxicity to plants 71
Application methods 71
Used with dichloropropane 71
Use rate . 71
Nematocide 198
Pest control 198
Toxicity to non-target organisms 198
Application methods 198
Fumigant 198
Chlorinated aliphatic nematocide 367
Eye irritation 367
Fumigant 3*/
Use in agriculture 367
Respiratory irritation 370
2,2-DICHLOROVlNYJ.
DIMETHYL PHOSi HATE
See DICHLORVOS
DICHtORVOS
Fly control for livestock 59
Fly control for dairy barns 59
Organophosphate 59
Organaphosphorous compound 64
Use rate 64
Quantities used, domestic 147
Insecticides, household use 151
Used with diazinon and chlordane 151
Acute oral toxicity, LD-50 312
Acute dermal toxicity, LD-50 312
Dermatitis, contact, allergic 364
Mutagenicity in higher plants 576
Chromosome aberrations in
nigher plants 583
Household use 611
Effects on onion chromosomes 640
Producers f*l
Application 647
27
-------
CHEMICAL SUBSTANCE INDEX
Patent number
Chemical name, structure
Physical properties
Product form
Oral toxicity, LD-50
Major end uses
DICOFOL
See KELTHANE
DICROTOPHOS
See BIDRIN
DICRYL
Herbicides, pre-emergent
Persistence
Toxicity
Use rate
Herbicides, amides
Use in agriculture
Use in home and garden
Tumorigenkity testing, results
Registered but not for use
on food crops
Tumorigericity testing, rating
Tumorigenicity testing, results
Testing for increase anomalies
DIELDR1N
Persistence
Environmental contamination
Needed knowledge of sample
composition, purity
Persistence
Decrease usage over next 2 years
Blood levels, measure of exposure
Toxicity, poisoning
Controlled human studies, results
Uses, usage
Use for termite control
Use, insect control
Usage, foreign countries
Replacement by, of new soil
insecticides
647
647
647
647
647
647
70
70
70
70
70
70
73
475
475
490
492
674
9
9
11
26
26
33
34
35
52
53
54
55
60
Chlorirated aryl hydrocarbons
Use
Effect of DDT upon storage of
Usage, .vorid crops
Cereal (.rops
Seed dressings, use to
control pests
Sugarcane crops
Use to control pests
Control of pests, resistant
to other pesticides
Locusts
Use to control insects
Termites
Use to control pests
Yellow fever and malaria
Use to control pests
{Tiaras disease
**••• 'Ufm * ' • '
Use to control pests
Sleeping sickness
Use to control pests
Grasshopper control
Persistence
Air transport of. analysis
in air
Atmospheric contamination
Ground waters
Transport through soil
Water samples, analysis
Potable water supply
Standards, limits
Concentrations in rice paddies
Water concentrations, analysis
Most frequently found pesticide
Examination of estuaries.
shellfish
Cucumbers grown on treated
soil, residues in
Residues in seed crops
63
63
81
84
85
86
89
89
89
90
90
90
90
91
91
91
91
91
91
91
104
113
114
116
116
117
121
122
125
128
129
129
132
133
28
-------
CHEMICAL SUBSTANCE INDEX
Dietary intake 136
Acceptable daL'y intake. FAO-WHO 137
Foods of aninuJ origin, source
of pesticides 138
Intake, human t 138
Residues in cow's milk 140
In runoff water 145
Leaching of pesticides from
soil by water 14S
Occupational exposure, workers,
health hazard 155
Persistence 180
Decrease usage over next 2 years 180
Deaths to wildlife 200
Effect on phytoplankton 207
In marine invertebrates 208
Mortality in crabs, feeding upon
fish killed by dieldrin 209
Effect on marine life 210
Fish kills 210
Bird poisoning 211
Exposure of biids to 212
Effect on mammals, occasional
mass mortalities 213
Blood levels, measure of c xposure 232
Toxicity, poisonings 233
Controlled human exposure 233
Actions to improve protection
of public health 239
No extension of present uses 239
Concentrations of residues in
tissues, rats, dogs 265
Concentrations in tissues 266
Concentrations of HEOD in blood
and other tissues, rats, dogs 267
Exposure of workmen, HEOD in
blood 268
Concentration in body fat of
animals vs concentration
indict 280
Studies in human volunteers 296
Experimental oral exposure 301
Concentration in adipose tissue 302
Estimated half-life, blood,
humans 302
Epidemics of poisoning 310
Acute oral toxicity, LD-50 313
Acute dermal toxicity, LD-50 313
U.S. pesticide production, annual 315
Adipose residues ."71
Personal variables, effect on 322
Sex differences, effect on 322
Age differences, effect on 323
Place variables, effect on 324
Secular changes, effect on 328
Comparison of human adipose
residues, DDT, dicSdrin 338
Comparison of human adipose
residues, DDT, dieldrin 339
Adipose residues, human 340
Adipose residues, human 341
Occupational exposure, humans 349
Occupational exposure, humans 351
Occupational!/ related skin
conditions 366
Bilateral retrobulbar ni-uritis
from mixture of chemicals 368
In human milk 374
U.S. pesticide production 382
Occupational exposure, humans,
residues in fat 383
In autopsy tissue 386
29
-------
CHEMICAL St'BST . NCE INDEX
Excretion of, residues of 388
Time trends of hazard 395
Penetration of 403
Sample skin matrix 405
Occupational exposure, results 409
Behavioral effects 413
Oral toxicity, rats, age effects 427
Concentrations in adipose tissue,
males vs females, humans 429
Dermal exposure, partially
hepatcctomized rats, toxicity 430
Nutrition, starvation, effect
on toxicity 431
Dietary protein, effect on
toxicity 432
Rats, effect on liver, duration
of exposure 43S
Liver changes, rats 435
Excretion in urine, occupationally
exposed vs general population 447
Occupational exposure, analysis
of blood 448
Tumorigenicity testing, results 470
Registered for use on food crops 470
Enzyme induction studies in
progress 520
Residues in consumer products 525
Storage, interaction of DDT.
dieldrin 527
Effect of chemicals on
dieldrin storage 528
Treatment of cows exposed to
aldrin-contaminated feed,
effect on dieldrin 529
Effect of surgical stress,
starvation on blood levels 530
Vitamin-A deficient rats.
effect on storage 530
Diet, effect on 532
Measurement in blood, body
burden of 537
Total daily intake 537
Occupational exposure, blood
levels, vs general population 538
H'jman volunteers, results 538
Effect of termination of exposure 539
Metabolism of 559
Effect on DNA 606
Organism tested, dose, effect 640
Products, producers 648
Application 648
U.S. patent number 648
Chemical name, formula 648
Physical properties 648
Product forms 648
Oral toxicity, LD-50 648
Major end-uses 648
Embryotoxicity in rats, dogs 664
Flacental transfer of 665
Study of stillbirths in cows 665
DIEPOXYBUTANE
Mutations in higher plants 583
Epoxidcs 583
Mutations in neurospora 585
Mutations 585
Chromosome aberrations in olants 591
Chromosome aberrations in
mammalian tissue culture cells 591
Mutagcnic effect 591
BIS (DIEThYLCARBAMOYL)
D1SULFIDE
DITHIOCARBAMATES
Tumorigenicity testing, rating
DIETHYL FUMARATE
Dermatitis
Intermediate product of malalhion
Scnsitization in humans
0.0-DIETHYL o.p-NFTRO-
PHENYL PHOSPHORO-
THIOATE
See PARATHION
491
364
399
399
30
-------
CHEMICAL SUBSTANCE INDEX
DIETHYLNTTROSAMINE
Carcinogen 261
DIETHYL 1,3-PROPANE-
DISULFCNATE
Mutations in higher plants 584
DIETHYLST1LBESTROL
Effect on DDT storage in rats 428
Cnzyme activity, rats 428
DIETHYL SULFATE
Mutations in higher plants 583
Mutations in barley 585
Mutations in neurospora 585
Mutations 585
DIETHYLSUCCINATE
Inhibition of aliesterase enzymes
by organophosphates 513
Human blood aliesterase activity
for substrates 514
DIETHYLTOLUAMIDE
Insect repellent 75
Insect repellent 611
Recommended for mutagenic
evaluation 611
D1FOLATAN
Teratogenic activity, chick
embryo 438
U-DIHYDRO-3,6-
PYRIDAZINEDIONE
See MALEIC HYDRAZIDE
DIHYDROSAFROLE
Use in preparation ot
piperonyl butoxide 541
Cancer of the esophagos, rats 543
Liver tumon in mice 544
Thin layer cinematography of
metabolites of 547
In rat bile, urine 547
Metabolism 548
Major metabolic pathway, in mice 548
DDSOPROPYL
FLUROPHOSPHATE
SeeDFP
DILANTIN
See DIPHENYLHYDANTOIN
DIMECRON
See PHOSPHAM1DON
DIMEFOX
Oiganophosphoms < ompound 444
Precautions for application 444
Organophosphorus compound 608
May affect DNA 608
DIMERCAPROL
SecBAL
D1METHOATE
Oiganophosphorous compounds 64
Use rate 64
Grasshopper control 91
Poor or lack of grasshopper
control 92
Action of EPN upon degradation of 513
Degradation of human liver 514
Amidase activity, humans, animals 514
May affect DNA 608
Organophosphate 608
Systemic insecticide 610
Use in agriculture 610
DIMETHRIN
Botanical insecticide 63
DIMETHYLAMMONIUM
DITH1OCARBAMATE
Tumorigenicity testing, rating 491
BIS (DIMETHYLCARBAMOYL)
DISULFIDE
DITHIOCARBAMATE
Tumorigenicity testing, rating 491
DrMETHYLNlTROSAMINE
Carcinogenic studies, mice
484
Formation of mutagenic metabolic
products from 594
DIMETHYLSULFOXIDE
SeeDMSO
DIMETILAN
Chemical structure
557
31
-------
CHEMICAL SUBSTANCE INDEX
Effects on DNA, Possible 607
Carbamates and thiocaibamates 607
DIMITE
Compound related to DDT 63
Uses 63
Use rate 63
DINITROBUTYLPHENOL
Miscellaneous insecticide 65
Limited use in agriculture 65
Use rate 65
DINITROCRESOL
Miscellaneous insecticides 65
Use in control of termites 65
Use rate 65
Nitrophenol compounds 65
Skin staining 370
Nitrophenois 370
Fatal cases 370
DINITROPHENOL
Dinitrophcnols, use in Germany 45
2,4-dinrtrophenol. use in
treatment of obeaty 368
Nitrophenois 368
Cataract development in U.S. 368
Nitrophenois 370
Respiratory iiritation 370
Skin staining 370
Treatment for poisoning, humans 450
Inhibition of oxidattve
phosphorybtion 604
DINITRO-O-PHENOL
Toxicity to rats, effect
of temperature 433
2,4. DINITROPHENOL
Oral agent, treatment of obesity 368
Cataracts from 368
2-SEC.-BUTYL-4.6-
DIMTROPHENOL
Tumongenicity testing, results 475
Registered but not for use on
food crops 475
DINOCAP
See KARATHANE
DINOSEB
Substituted phenolic nerbicides 69
Uses 69
Persistence in soil 69
Non-transloiation in plants 69
Toxicity to mammals 69
Herbicides 203
Hazard:- to non-target organisms 203
Toxicity to aquatic animals 203
Toxicity to terrestial animals 203
Degradation 203
Contamination of lakes, streams 203
Toxicity to non-target organisms 205
Plant growth regulators 205
Toxicit/to fish 205
Degradation of 205
Precautions, water contamination 205
DIPHACIN
Anticoagulant rodenticides 72
Properties 72
Action 72
Symptoms of death 72
Precai tions for use 72
DIPHACINONE
See DI?HACIN
DIPHENAMID
Amide: 70
Herbicide 70
Uses 70
Persistence in sofl 70
Use rates 70
Toxicity 70
DIPHENATRILE
Tumongenicity testing, results 475
Registered but not for use on
food crops 475
DIPHENYL
Miscellaneous fungicides 67
Uses 67
Use rate 67
DIPHENYLHYDANTOIN
Effect on residues of DDT
and metabolites, humans 323
Effect on DDE blood
levels, humans 436
Use in controlling convulsions 451
32
-------
CHEMICAL SUBSTANCE INDEX
Effect on DDE blood levels 529
DIPTEREX
Acute oral toxicity, LD-SO 312
Acute dermal toxicity. LD-SO 312
DIQUAT
Herbicides 70
Mammalian toxicity 70
Use in agriculture 70
Use in industry 70
Herbicide, aquatic 205
Toxicity to fish, wildlife 205
Nitrogen compounds 365
Effects on skin and nails, humans 365
Effects of paraquat/diquat
mixtuii in humans 368
Effects on eye, human 368
Effects on fingernails 405
Mechanisrt of action, possible 405
Effects on DNA, possible 607
Bipyridiu n quaternary salts 607
Effects or, plants 607
DISODIUM METHANE
ARSONATE
Metal organic compounds 68
Uses 68
DISULFOTON
Plant systemic insecticides 60
Replacement for aldrin, dkldrin 60
Organophosphorus compounds 364
Cholinesterase inhibitors 364
Effects 364
Systemic insecticide 610
Use in agriculture 610
Di-SYSTON
Acute otal toxicity, LD-SO 312
Acute dermal toxicity LD-SO 312
Phosphate ester pesticide 312
DITHANE Z-78
SeeZINEB
DfTRANIL
See DICHLORAN
DIURON
Substituted ureas 69
Absorption plant through roots 69
Persistence 69
Tumorigenicity testing, results 475
Registered for use on food crops 475
Tumorigenicity testing, rating 490
Ureas 492
Tumorigenicity testing 492
May affect DNA 608
Testing for increase anomalies 673
D1ZANE
Diphenyl aliphatic chlorinated
hydrocarbons 63
Compounds related to DDT 63
Use rates 63
Uses 63
DMBA
Persistence in mice, age groups 484
DMSO
Effect on percutaneous
penetration of Seman 403 .,
Effect on potency ratio of Seman 403
Effect on LD-SO 403
Effect on spontaneous
motor activity .rats 417
Effect on hexobarbital
steeping time, rats 417
Effect on conditioned avoidance
response, rats 417
Solvent for 2,4,5-T studies 666
Effect on Utters, mice 667
Effect on fetal abnormalities 667
Solvent for increase
abnormality testing 670
DNOC
Toxicity to rats,
effect of temperature 433
Urine, indicator of exposure 448
Method, blood analysis 448
DNPB
SeeDINOSEB
33
-------
CHEMICAL SUBSTANCE INDEX
DODINE
Fungicides, niiscellaneous
group 67
Uses 67
Use rates 67
Tumorigenicity testing, judged
not positive 475
Registered for use on ibod crops 475
U.S. sales, use in agriculture 610
Fungicide 610
DOWCIDE A
Miscellaneous fungicides 67
Uses 67
Use rates 67
DOWCIDE-7
Tumorigenicity testing, results 475
Registered but not for uje
on food crops 475
Use in food containers
and packaging materials 475
DOWFUME MC-33
Halogenalcd hydrocarbon
nematocides 71
Persistence 71
Toxic:ty to plants 71
Toxicity to humans 71
Mixtures of compounds 71
Application rates 71
DCWPON
Aliphatic acid herbicides 69
Toxicity to broad leaf plants 69
Toxicity to grass 69
Use rates 69
Use in agriculture 69
Use as soil sterilants 69
Toxicity to humans 69
Toxicity to warm-blooded animals _ 69
2-(2.4-DP)
Tumoiigenicity testing, results 474
Registered for use on food crops 474
DURSBAN
Organophosphates 64
Heterocyclic derivatives 64
Use in agriculture 64
Use rate 64
Use in mosquito control 127
DU-TER
Kstal organic fungicides 66
Uses 66
Use rules *6
DYBAR
See FENURON
DYLOX
See TRICHLORFON
DYM1D
See DiPHENAMID
DYREN>-
Chlorine containing fungicides 67
Uses 67
Use rates 67
E-605
See PARATHION
ECHOTHIOPHATE IODIDE
Use in glaucoma 412
Effect on human red blood
cell cholir.esterase 412
Symptoms in humans 412
EDTA
Use in heavy metal poisoning 452
Routes of administration 452
delation of copper, lead,
manganese, mercury and zinc 452
Mechanism of action 452
ELCIDE
May sffect DNA 60S
Mercurial 608
EMBUTOX E
Mutation! in barley 584
EMMI
Organic mercury compounds 66
Use as fungicides for
«ed treatment 66
Use a fungicides for bulb
and corm treatment 66
Use in agriculture - 66
Use rates 66
Mercurials 608
May affect DNA 608
ENDOSULFAN
Tumorigenicity testing,; .suits 475
Registered for use on fc id crops 475
Tumorigenicity testing, rating 490
ENDOTHALL
Phthalic acid compounds 68
34
-------
CHEMICAL SUBSTANCE INDEX
Herbicides, preerr.ergence
Persistence in soil
Toxicity-to mammals
Use in agriculture
Use rates
Organism tested, dose, effect
Products, producers
Application
Chemical name, structure
Physical properties
Product forms
Oral toxicity, LD-50
Major end uses
ENDRIN
Persistence
Persistent chlorinated
hydrocarbons
Recommended decrease usage
over next 2 yean
Poisoning cases
Usage, U.S. Dept. of Agriculture
survey
Usage
Chlorinated aryl hydrocarbons
Use in agriculture
Use on crops in the world
Rice crops
Use to control insects
Sugarcane
Use to control insects
Cyclodiene organuchlorines
Pesticide pollution of
ground waters
Water pollution from spraying,
persistence
Limits, potable water supply
Spraying field, concentration
in water
Concentrations in water
Concentrations in shellfish
Concentrations in river basins
68
68
68
68
68
640
Concentrations in cow's milk 140
Health hazards associated
with agriculture use 155
Exposure of workers 156
Accidental exposure.
648
64ft
648
648
648
648
648
26
26
34
47
52
63
63
84
85
85
89
89
104
117
120
121
125
129
129
flour contamination
Persistent chlorinated
hydrocarbons
Recommended decrease usage
over next 2 years
Effect on phytoplankton
Concentiation by marine
organisms
Effect or. shrimp
Toxicity to mammals
Poisoning cases
Epidemics of poisoning
by pesticides
Acute oral toxicity
Acute dermal toxicity
Chlorinated h>^ocarbon
pesticides
U.S. pesticide production.
annual
Diene group
Effect on workers
Study of workers exposed
to pesticides
Effect on excitability
of nervous system
Reports of occupationally
related skin conditions
Analysts of tissues
Effect on monkeys
Poryn
-------
CHEMICAL SUBSTANCE INDEX
Induction of mutations
U.S. sales, use in agriculture
Effect on bailey
Products
Patent number
Chemical name, formula
Physical properties
Product form
Oral toxicity LD-50
Major end uses
ENT-50612
Mutations in barley
EPN
Behavioral changes reported
Human exposure
Acute oral toxicity to
adult rats
Acute oral toxicity to
weanling rats
Toxicity in young malr rats
Toxicity in aJult male rats
Conversion to anticholinesterase
agents in rat liven
Urine, indicator of exposure
Urine, indicator of exposure
p-nitrophenol in urine,
indicator
Potentiatfofi, administered
with malathion
Acute toxicity, in combination
with mala thion
Metabolite of EPN, inhibitory
effect on aliestrrase
In combination with malathion
Mechanism of action
Mechanism of EPN potenbation
of malathion
Synergism with malathion
Mechanism of action
Organophosphates
Tentogenic. chick embryo
EFTAM
Carbamates
Agricultural herbicide
606
610
640
648
648
648
648
648
648
648
584
413
413
427
427
427
427
428
447
448
448
512
512
513
513
513
513
523
523
665
665
70
70
Use rate
Persistence in soil
Toxicity to humans
Toxicity to warm-blooded animals
EPTC
Sc-rEPTAM
ER3ON
Phenoxy herbicides
Used for broadleaf werd control
Used for woody plant control
Systemic herbicide
Persistence in soil
Toxkity to humans
Toxicity to other animals
Use rates
8-ETHOXYCAFFEINE
Purine
Chromosome aberrations in
higher plants
Chromosome effects
Mutagcnic effect
ETHYL CARBAMATE
Rate of metabolism
Carcinogenesis
Catabolic rate in adult mice
Catabolic rate in newborn mice
Carcinogenic action
Tumorigenicity testing, rating
Tumorigenk
Effect on DNA, possible
Production of chromosome breaks
ETHYL ETHANESULFONATE
Mutations
ETHYL FENTHION
Toxicity in young male rats
Toxicity in adult mate rats
Toxicity to female rats, male
and female mice, male
guinea pigs
Toxicity to mate rats
ETHYL HEXANEDIOL(6-12)
Insect repellents
Human exposure
Recommended for mutagenic
testing
70
70
70
70
68
68
68
68
68
68
68
68
5S4
584
591
591
484
484
484
484
484
491
491
606
606
585
427
427
429
429
75
611
611
36
-------
CHEMICAL SUBSTANCE INDEX
ETHYL MERCURY
Organic mercury compounds 66
Use as fungicide 66
Use ntes 66
Ethyi mercury chloride,
organism, dose, effect 640
Products, producers 649
Application 649
Chemical name, formula 649
Physical properties 649
Product form 649
Major end uses 649
ETHYL MERCURIC
PHOSPHATE
Mercury compound S83
Chromosome aberrations in
higher plants 583
ETHYL METHANESULFONATE
Induction of mutations 578
Mutations in higher plants 584
Mutations 585
Testing for mutagcnicity 595
ETHYL PARATHION
See I'ARATHION
ETHYLENE CHLOROHYDRIN
Fumigants 612
Formation of 612
Persistence in marketed
materials 612
Induction of mutations
inNeurospora 612
ETHYLENE DIBROMIDK
Halogen? ted hydrocarbon
ncmatocides 71
Persistence 71
Toxkity to plants 71
Toxkity to humans 71
Use ntes 71
Volatile fumigants 198
Persistence in soil 198
Effect on soil organisms 198
Residue in soil 198
Bromide absorption from sofl
by certain plants 198
Method of application to soil 198
Effect on DNA 606
Fumigant
Mutagcnic at"ion in Neurospora
ETHYLENEIMINE
Mutations in higher plants
Mutations
Effect on DNA
Etliyleneimincs
Testing for abnormal fetviss
ETHYLENE OXIDE
Mutations in higher plants
Chromosome aberrations in
higher plants
Mutations
Effect on DNA
Epoxides
Fumigants
Breakdown
Alkylating agent
Muftgenic action
Organism tested, dose, tffcct
Products, producers
Application
Chemical name, formula
Physical properties
Product form
Major end uses
ETHYLENE TH10UREA
Ureas
Oxidation product of nabam
Tumorigenicity
FEKEMA ES-30-9
Effect on human hair follicles
Ingredients of
FENITROTHION
Morbidity surveys of workers
Occupational exposure
Organophosphate compoun A
Health effects of workers
FENTHION
Organic phosphates,
phenyl derivatives
Use rates
Queletox. formulation of Baytex,
use in bird control
612
612
583
585
606
606
669
583
583
585
606
606
612
612
612
612
640
649
649
649
649
649
649
492
492
492
405
405
345
345
345
345
64
64
73
37
-------
CHEMICAL SUBSTANCE INDEX
Mosquito control 127
Effect on crab larvae 209
Morbidity effects of
occupational exposure 345
Morbidity surveys 345
Occupational exposure 345
Health effects of
occupational exposure 345
FENURON
Substituted urea herbicides 69
Absorption through plant roots 69
Persistence in soil 69
Use rates 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
Ureas 608
May affect DNA 6CS
FERBAM
Dithiocarbamate fungicide 66
Used as soil drench 66
Use rates 66
U.S. pesticide annual
production 315
U.S. pesticide production, 1966 382
Poisoning prevention and
treatment 452
Use of deferoxamine in
poisoning treatment 452
Treatment of acute intoxication 452
Fungicide 452
Tnmorigenicity testing, results 475
Registered for use on food crops 475
Organism tested, dose, effect 640
Products, producers 649
Application 649
US. patent number 649
Chemical name, formula 649
Physical properties 649
Product form 649
Oral toxh-.ty. LD-50 649
Major end uses 649
Testing for increase anomalies 673
FERMATE
See FERBAM
FERRIC DIMETHYL
DITHIOCARBAMATE
See FERBAM
FLUOMETURON
Substituted ureas herbicides 69
Soil persistence 69
Absorption through plant roots 69
Use rates 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
FLUORIDE
Fluoride rodenticides 72
Toxicity to warm-blooded animals 72
Application restricted to
licensed operators 72
Properties 72
Insecticides for household use 151
Sodium fluoride, use as
insecticide 151
Sodium fluoride, mixed with
pyrethrum for dusting 151
Deaths from ingestion 158.
FLUOROACETAM1DE
Fluoride rodenticides 72
Toxicity to warm-blooded animals 72
Restricted use 72
Properties 72
Organs affected 72
FLUOROAKIL 100
See FLUOROACETAMIDE
5-FLUORODEOXYURIDINE
Chromosome aberrations in
higher plants 584
Chromosome effects 591
FLUOROOROTIC ACID
Effect on DNA 607
S-FLUOROURACIL
Effect on DNA 607
FOLEX
Acute toxicity to rats 427
Toxicity to weanling rats 427
Toxicity to adult rats 427
FOLPET
Needed knowledge of sample
composition, purity 11
38
-------
CHEMICAL SUBSTANCE INDEX
Chlorine-containing fungicides 67
Use 67
Use rate 67
Dermatitis in agricultural
workers 399
Teratogenic activity, developing
chick embryo 438
Tumorigcnicity testing, results 475
Registered for use on food crops 475
Tumorigenicity testing, rating 490
Recommendation for
teratogenicity testing 658
Teratogcnicity 658
Teratogenic in chicken embryo 66*
Teratogenicity in mice 664
Incidence of abnormal fetuses 666
Testing for increase anomalies 673
FORMALDEHYDE
Fumigants 612
Mutagenic action 612
Organism tested, dose, effect 640
Products, producers 649
Application 649
Chemical name, formula 649
Physical properties 649
Product form 649
Toxkity to plant j, animals 649
Major end uses 649
FORMALIN
See FORMALDEHYDE
FREON112
In combination with piperonyl
butoxide 545
Hepatomas >n mice 545
Acute toxicity in combination
with piperonyl butoxide
FREONI13
Acute toxicity in combination
with 3,4 benzpyrene
FUdR
See 5-FLUORODEOXY-
URIDINE
546
546
FUMARIN
Anticoagulant rodenticides 72
PK t~T»ies 72
Ac ac.-> 72
Death, *- -m internal hemorrhage 72
Frrcautioas i - use 72
Poisoning in hum-. <.< 158
FUR/DAN
Ca/bamates, mechanitm of action 65
Use in agriculture 65
Use rates 65
Effects on DNA, possible 606
Systemic insecticide 610
Use 610
GAMMA BENZENE
HEXACHLORIDE
See LINDANE
GARDONA
Control of grasshoppers (Tucura)
in Argentina 92
Poor or lack of grasshopper
control 92
GEN1TE R-99
Tumorigenicity testing, results 473
Registered but not for use on
food crops 473
Tumorigenicity testing, rating 490
GENTIAN VIOLET
Rosanfline dyes 364
Skin irritation, low
concentrations • 364
Hemorrhages in skin,
high concentrations 364
Hemorrhages in mucous membranes 364
Occupational exposure 364
Accidental exposure 364
Conjunctivitis
Exposure to dust in air
Symptom from exposure
GESATAMIN
See ATRATRONE
GIBBERELUC ACID
GibbereQins
Responses in plants
Use rate, application
368
368
368
74
74
74
39
-------
CHEMICAL SUBSTANCE INDEX
Tumorigencity testing, results 473
Registered for use on food crops 473
GIBBERELLIN A3
See GIBBERELLIC ACID
GLYCIDOL
Epoxides 58?
Mutations In higher plants 283
Mutation* in barley S8S
Mutations in Neurospon 585
Mutations 585
GLYODIN
Miscellaneous fungicides 67
Use in agriculture 67
Uses 67
Use rate 67
Tumorigeiucity testing, rating 475
Registered for use on food crops 475
GRANOSAN
See ETHYLMERCURY
CHLORIDE
GR1SEOFULV1N
Hepatocarcinogenicity 485
Interactions .• 546
Interaction with
piperonyl butoxide 546
Mortality effects 546
Effects on weight in mice 546
May affect DNA 609
GUTHION
Organic phosphate pesticides 64
Use in home 64
Use in garden 64
Use rate 64
Residues in milk 140
Feeding of contaminated forage 140
Metabolites 140
I
Half-life values on fruits 142
Residues, affected by rainfaO
or wishing 142
Persistence on fruits 142
Persistence of granular
applications 143
Acute oral toxsrity. LD-SO 312
Acute dermal toxkity. LD-50 312
Occupational!/ related skin
conditions 366
Psychiatric disorders 413
M-tjbolism, by various animals 426
Conversion in rats 428
Toxicity to rats,
temperature effects 432
Enzyme induction, effects on
toxkity 518
May affect DNA 608
Us>; in agriculture, insecticide 610
Te/atogenk in chick embryos 665
Teratogenic in mice 665
GYPLURE
Synthetic attractants 75
U-c in control of fruit flies 75
HCN
Set HYDROGEN CYANIDE
HEOD
Concentrations in tissues of
Tits, dogs 265
Relation of concentrations in
tissues to dietar> intake 265
Concentrations in tissues
of rats, dogs 266
Administered to volunteers 267
Concentrations in blood 267
Correlation with other tissues 267
Concentrations in tissues of rats 268
Concentrations in blood of
volunteers 268
Concentration in tissues vs
exposure 269
Studies of, in cow's milk
and eggs 269
Concentrations in tissue* 270
Model, experimental results 272
Studies in animals, implications 273
40
-------
CHEMICAL SUBSTANCE INDEX
Tissue concentrations vs
daily intake 279
Concentration in tissues vs
time of ings' on 284
Concentration h body fat
vs liver 285
Concentration in adipose tissue
dui jig post exposure 292
Concentration in blood, liver
during post exposure 293
Concentration in human blood
industrial exposure
terminated 294
Residues, no sr.x differences
in U.S. 322
Levels in Great Britain 328
Readues in human tissues 386
Reidue of aldrin and dieldrin 386
HEPTACHLOR
Persistence 9
Contamination of environment 9
Persistence ' 26
Decrease usage over next 2 years 26
Insecticides, use in U.S. 48
Uses 48
Uses 52
Residues 52
MetaKilite heptachlor epoxide 52
Residues fa milk S3
Use for termite control 53
Usage of insecticides,
foreign countries 55
Chlorinated aryl hydrocarbons 63
Use in agriculture 63
Usage, world crops 84
Cereals, use to control pests 86
Sugar beet, use to control pests 88
Sugarcane, use to control pests 89
Grasshopper control 91
Use banned, residues 91
Persistence 104
Ground waters, contamination of 116
Ground water, analysis of 117
Potable water supply 122
Standards, limits 122
Water concentrations 128
Examination of estuaries 129
Transport from soil to plants 132
Residues in soil, seeds 133
Plants, conversion of heptachlor
to heptachlor epoxide 133
Dietary intake 136
Dietary intake. FAO-WHO 137
Cows, grazing on treated fields,
residues in meat 139
Uptake by plants 144
Persistence 180
Decrease usage over next 2 years 180
Deaths of wild animals, birds 200
Effect on phytopbnkton 207
Effect on shrimp 209
Effect on quail population 211
Actions to improve public Iicalth 239
No extension of present uses 239
Acute oral toxicity, LD-50 313
Acute dermal toxicity, LD-50 313
U.S. pesticide production,
annual 315
Effect on excitability of the
nervous system 360
Examination of autopsy tissues
for 386
Tumorigenicity testing, ratin-
of heptachlor epoxide 470
Registered for use on food crops 470
41
-------
CHEMICAL SUBSTANCE I1IDEX
Enzyme induction measurements
in progress
Rats, in combination with DDT,
residues in adipose tissue
May affect DNA
Insecticides, use in
agriculture
HEPTACHLOR EPOXIDE
Needed knowledge of sample
composition, purity
Metabolite of hcplachlor
Residues, concern of
Found in dust from storm
Transport in air
Concentrations in lakes, plan's
Potable water supply
Standards, limits
Water concentrations
Examination of shellfish for
estuary contamination
Concentrations of, in alfalfa,
in field containing
heptachlor
Residues in seed crops
Conversion to in plants.
from heptachlcr
Vapor pressure
Half-life
Acceptable daily intake,
FAO-WHO
Foods of animal origin
Source of, in diet
Residues of, in fatty tissue
of cattle
Detection of, FDA Pesticide
Analytical Manual
Actions to improve protection
of public health
No extension of present uses
Residues in human adipose tissue
Human pesticide residues
520
527
609
610
11
Residues, human adipose tissue 331
Efff ot on excitability of CNS 360
Detection in human tissues 387
Storage of, in males vs females 429
Concentration of, in human milk 449
Relationship to other chemicals 449
Judged positive for tumor
induction 470
Enzyme induction studies
52
52
113
113
119
122
122
128
129
133
133
1 1^
133
101
133
133
137
138
1 tO
138
139
239
239
269
320
in progress
Residues in human tissues
Residues in human tissues
Not commonly used in
household formulations
DELTA-HEPTACHLORO-
CYCLOHEXANE
Occupational exposure to lindane
Dermatitis from impurity in
lindane, humans
HERBAN
See NOREA
HERCULES 7531
See NOREA
HEXACHLOROBENZENE
Chlorine containing fungicides
Use in agriculture
Use rates
Epidemics of poisoning
Porphyria following ingestion of
Contaminated grain, human
ingestion
Effects of ingestion by humans
Effects of exposure, occupational
Contaminated grain.
human ingestion
Photoscnsitivity in rats
Induced porphyria
1,2,3,4,5.6-HEXACHLORO-
CYCLOHEXANE
Sec UNDANE
520
525
538
538
363
363
67
67
67
311
350
364
364
365
372
433
433
42
-------
CHEMICAL SUBSTANCE INDEX
HEXOBARBITAL
Rat sleeping time,
effect of DMSO
Sleeping time, effect of
organic phosphates
Metabolism by liver
microsomal enzymes
Enzyme induction
417
518
520
520
Sleeping time, effect of
pipcronyl butoxide and sesamex 546
Mouse liver mioosomes 554
HMPA
Se; PHORATE
HYDRAZIKE
Hydrazine derivatives 492
Hydiazine, hepatomas iii mice 492
Free hydrazine liberation 492
Mutations in higher-plants 583
Effect on DNA 606
HYDROCYANIC ACID
See HYDROGEN CYANIDE
HYDROGEN CYANIDE
Inorganic compounds,
u:e as pesticides 45
Introduction in 1886 45
Cont:ol of scale insects
in California 45
Resistance of insects to chemical 45
Use before World War II
as insecticide 45
Funujants 65
Use in agriculture 65
Use in public health 65
Use rates 65
Effect on mammalian embryo cells 640
Products, producers
Application
Chemical name, formula
Physical properties
Oral toxicity. LD-50
Major end uses
649
649
649
649
649
649
NX2-HYDROXYETHYL)-
HYDRAZINE
Needed knowledge of sample
composition, purity 11
Tumorigenicuy testing, results
Registered b-Jt not for use
on food crops
Hydiazine derivatives
Tumorigeniciiy in mice
BETA-HYDPOXYETHYL
METHANE SULFONATE
Mutations in higher plants
HYDROXYLAMINE
Chromosome effects
Mutagenk effect
DNA alterations
HYDROXYUREA
Chromosome aberrations in
higher plaits
HYVAR
Mutagenic in plants
BETA-INDOLEaUTYRIC
ACID
Auxins
Auxins
Use rates
Uses
IOXYNIL
Nitrite herbicides
Preemergence herbicide
Toxicity to mammals
SoD persistence
Use rates
Effect on DNA, possible
IPC
See PROPHAM
IPECAC, SYRUP of
Emetic
Use in poisoning cases
IRON DITHIOCARBAMATE
Tumorigenicity testing, raring
ISOCIL
Base analogs
May affect DNA
Organism tested, dose, effect
ISODRIN
Chlorinated cydodienes
470
470
492
492
584
591
591
604
583
576
74
74
74
74
70
70
70
70
70
607
450
450
491
609
609
640
609
43
-------
CHEMICAL SUBSTANCE INDEX
May affect DNA 609
I SOLAN
Tumorigenicity testing, results 475
Registered but not for use
on food crops 475
Tumorigenicity testing, rating 491
ISOPESTOX
See MIPAFOX
2-ISOPROPOXYPHENYL
N-METHYL CARBAMATE
See BAYGON
ISOPROPYL
m-CHLOROCARBANILATE
See CHLORPROPHAM
ISOPROPYL METHANE
Sl'LFONATE
M itations in higher plants 584
Mutations in barley 585
Potential mutagenic compounds 595
Mutagcnic testing 595
ISOPROPYL
N-PHENYLCARBAMATE
See PROPHAM
ISOPROPYLPHENYL
CARBAMATE
Chromosome aberrations in
higher plants 583
1SOSAFROLE
MDP synergists, prepared from
isosafrole 542
Study of liver tumorigenicity 544
Metabolites, use of thin-layer
chromatography 547
Metabolites 548
2-ISOVALOYL-13-
INOANEDIONE
Sec VALONE
KAPATHANE
Related to DDT 63
Use rates as insecticides 63
Use rate as miticidcs 63
Miscellaneous fungicides 67
Use in agriculture 67
Uses 67
Use rate 67
Turaorigcnicity testing, results 475
Registered but not for use on
food crops 475
KARMEX
See DIURON
KELTHANE
Compounds related to DDT 63
Use rates as insecticides 63
Use rates as miticidcs 63
Accidents, by industry,
by occupation 154
Acute oral toxicity, LD-50 313
Acute dermal toxicity. LD-50 313
OccupationaUy related
skin conditions 366
U.S. sales, use in agriculture 610
fcisectjc'de 610
Organochlorine 664
Teratogenicity in mice 664
KEPONE
Insecticides for household use 151
Pellets us baits 151
Onset of action 151
Anticoagulants 151
Use in rodent control 151
Toxicity 151
Resistance of some rodents 151
Embryotoxicity in rats 664
Embryo toxicity in dogs 664
Organochlorines 664
KEROSENE
Pesticides before 1945 45
Introduction in 18th century 45
Toxicity to plants 45
Toxicity to insects 45
Use as larvicidcs for mosquitoes 45
Behavioral effects of solvents 417
Signs and symptoms 417
KOCN
Organism tested, dose, effect 640
44
-------
CHEMICAL SUBSTANCE INDEX
Produc ts, producers 650
Application 650
Oiemicil name, formula 650
Physic?.! properties 650
Product form 650
Oral toxicity. LD-50 650
Major end uses 650
KURON
I 'rine, indicator of exposure 448
LAMPRICIDE L-30-F
Use in control of stream lampreys 73
LANNATE
Carbamates 65
Action 65
Major use in agriculture 65
Use rate: 65
Treatment of poisoning with
TEAC, in mice 454
LANS! AN
Chlorine-containing fungicides 67
Use in agriculture 67
Use rate-. 67
LASSO
Amides 70
Use as herbicides 70
Use as precmergent herbicide 70
Persistence in soil 70
Use rates 70
Toxicity 70
LAVOZIL
Base analogs 609
Conversion into cpoxide 609
May affect DNA 609
LEAD
Persistence 9
Environmental contamination 9
Lead arsenate, introduction
as insecticide against
gypsy moth, 1892 45
Persistent pesticides 105
Toxic elements 105
Water solubility 105
Persistent pesticides 145
Accidents, by industry.
by occupation 154
Lead arsenate. U.S.
pesticide production, 1966 315
Occupational^ related skin
conditions 366
Lead arsenate, U.S. pesticide
production, 1966 382
Urine, indicate, of exposure 448
Treatment of pc isoning 451
Lead dithiocartxunate 491
Tumorigenicity, rating 491
LEAD ARSENATE
Inorganic compounds 45
Use as insecticide against
gypsy moth 45
Introduction in 1892 45
Inorganic insecticides 62
Use on trees and shrubs to
control chewing insects 62
Use in baits for control of
ants and cockroaches 62
U.S. pesticide production 315
U.S. pesticide production, 1966 382
Case of damage to nervous system 413
491
LEAD DiTHlOCARBAMATE
Tumorigenicity testing, rating
LENOCIL
Base analogs
Conversion into rpoxidcs
May affect DNA
LETHANF.
Fumigants
Use in agriculture
Use in public health
Use rate
Ingredient in fly sprays
UME SULFUR
Inorganic pesticides
Use against scale insects
Pest resistence, 1908
Resistance by San Jose
scale insect
609
609
609
65
65
65
65
65
45
45
59
59
45
-------
CHEMICAL SUBSTANCE INDEX
Inorganic fungicides 66
Use in cgriculture 66
Use rates 66
LINDANE
Persistence 9
Contamination of environment 9
Evaporation of, toxicity 23
Discontinue use, human exposure 23
Hematological disorders 34
Use on world crops 84
Sugarcane 89
Use of lindane to control pests 89
Chagas disease 91
Spraying of homes with gamma
BHC 91
Evaporation "f, toxicity 102
Discontinue use, human exposure 102
Pesticides in rainwater,
gamma BHC 116
Termite control, label
including lindane 117
Concentration in lakes, plants 119
Potable water supply 122
Standards, limiting
concentrations 122
Water concentrations 128
Most frequently found pesticide 128
Examination of shellfish for
estuary contamination 129
Intake in diet 136
Diet-r ' intake. FAO-WHO 137
Residue retention in cow's mflk 140
Exposure to, from home
, vaporizers 149
Concentration in homes,
manufacturing plants 149
Accidents, by industry,
by occupation 1S4
Effect on phytoplankton 207
Effect on shrimp 209
H^.natological disorders 233
Actions to improve protection
of public health 239
No extension of present uses
of lindane 239
Residues in human adipose tissue 269
Anite oral toxicity, LD-50 313
Acute dermal toxicity, LD-50 313
Human pesticide residues 320
Human adipose residues 331
Blood dyscraaas 350
Effects, human population 352
Dermatitis in workers, impurity
in lindane 363
Occupationally related skin
conditions 366
Ef'ect of thermal decomposition
products of lindane on
rcspintory tract 369
Hematological disorders 372
Detected in body tissues 386
Blood dyscrasias 388
Prociuc lion of liver changes, rats 435
Enzyme induction studies, in
progress 520
Feeding to rats, effect on
subsequent parathion
poisoning 524
Residues 525
Stoiage of. effect of fat
in diet 526
DDT, effect on metabolism of
lindane 528
Storage of, by rats, on
fat diets 530
46
-------
CHEMICAL SUBSTANCE INDEX
Etfrct oflow protein diets
on acute toxic effects
Daily intake of, actual vs
calculated levels
Mutagenic in plants
Organisms tested, dose,
biological effect
Products, producers
Chemical name, formula
Physical properties
Product forms
Oraltoxicity
Major end uses
L1NURON
Substituted ureas
Absorption through plant roots
Persistence in soil
Toxicity to warm-blooded animals
ToxJchy to fish
Mutitions in barley
Organism tested, dose, effects
May affect DNA
Products, producers
Application
Chemical name, structure
Physical properties
Prod, ict form
Oral toxicity, LD-50
Major end uses
LOROX
SeeUNURON
MALATHION
Mosquito control
Insect control, non-persistent
532
537
576
641
650
650
650
650
650
fen
650
69
69
69
69
69
584
642
608
650
650
650
650
650
650
650
Mosquito control
Daily intake
Acceptable daily intake.
WHO-FAO
Contribution to dietary intake
Effect of storage on residue?
Use, domestic
Effect on crab larvae
Acute oral U ijcity, LD-50
Acute dermal toxicity, LD-50
U.S. pesticide production, annual
Morbidity eifccts of
occupational exposure
Peripheral neuropathy
Effect on gastrointestinal tract
Sensitizcr in humans
Occupational^ related
skin conditions
Occupational exposure, effects
Intermediary product, diethyl
fumarate, sensitization
Penetration of
Sample skin matrix, effects of
127
136
137
138
141
147
209
312
312
315
345
360
361
364
366
399
399
403
405
54
59
Aliphatic derivatives.
organophosphorus compounds 64
Uses 64
Use rate 64
Use in grasshopper control 91
Non-persistent pesticide 104
Uses 104
Atmospheric contamination 114
Behavioral changes,
chemicals suspected 413
Oral toxicity to rats,
comparative 427
Effect of temperature on
toxicity, rats 432
Urine, indicator of exposure 448
Urinary exaction of 448
Administration with EPN,
effect on toxicity 512
Potentiators of malathion
toxicity S12
47
-------
CHEMICAL SUBSTANCE INDEX
Hydrolysis of 513
Toxicity io rats 514
Toxicity to humans 514
Interaction with EPN 523
Effect of temperature on
toxicity. MIS 533
Use in agriculture 610
Insecticide 610
Need for mutagcnic testing 611
MALEICHYDRAZIDE
Growth retaidant 74
Uses 74
Tumorigenicity testing, results 475
Registered for use on food crcps 475
Non-tumorigenic in mice 492
Mutations in higher plants 583
Chromosome aberrations
in higher plants 583
Chromosome aberrations in plants 591
Structure-activity-relationships 604
Chromosome breakage 607
Chromosome breakage in pLi ^ts 612
Organism tested, dose, effect 642
Products, producers 651
U.S. patent number 651
Chemical name, structure 651
Physical properties 651
Product form 651
Oral toxicity, LD-SO 651
Major end uses 651
MANEB
Stability 66
Dithiocarbamate fungicides 66
Use in agriculture 66
Use rates 66
Tumorigenicity testing, results 475
Registered for use on food oops 475
MANGANESE
Poisonings by heavy metal,
derivatives of 451
dictation with EDTA 452
MANGANESE FTHYLENE
(BISI DITHIOCARBAMATE
Tumorigenicity testing, rating 491
MANZATE
Sec MANEB
MARLATE
Sec METHOXYCHLOR
M/TACIL
Carbamate insecticide 72
{.'-. in control of garden snails 72
Use in control of slugs 72
Toxicity 454
Production of death in mice 454
Effect of tctraethylammonium
chloride on 454
MCPA
°henoxy herbicides 68
Uses 68
Systemic herbic'de 68
Persistence in soil 68
Toxicity to humans 68
Toxicity to animals 68
Use rate 68
Disappearance in soil 203
Effect of soil microorganism: 203
Effect on earthworm population 204
MECLURE
Synthetic attractants 75
Use in control of fruit flies 75
Use in control of melon flies 75
Use in control of
Mediterranean fruit fly 75
MEMMI
Organic mercury compounds 66
Use as fungicides for
reed treatment 66
Use in L Jb and corm treatment 66
Use in agriculture 66
Use rates '. 66
2-MERCAPTOBENZO-
THIAZOLE
Tumorigenicity testing, results 473
Registered for use on food crops 473
MERCURIC CHLORIDE
Inorganic fungicide 66
48
-------
CHEMICAL SUBST. NCE INDEX
Uses 66
Use rate 66
MERCURY
Salts of heavy metals, other
than mercury, use review
periodically 10
Persistence of in soil, salts of 45
Volatilization in air 45
Persistence 105
Toxicity 105
Persistence 145
Fungicides 202
Organic mercury, epidemics
of poisoning 311
Organic mercury compounds
occupationally related
skin conditions 366
Urine, indicator of exposure 44 8
Saliva, appearance in 448
Diagnostic use in poisoning 448
Treatment of poisonings 451
Mercury compounds 583
Mutagenic effects in plants 583
Chromosome effects in plants 583
Pesticides containing mercury 612
Production of, uses 612
Deaths, tcrotological effects
in Japan, seafoods 612
Minamata disease 661
Mercury containing pesticides,
results of studies 664
MESURAL
Chemical structure of 557
META-SYSTOX-R
Aliphatic derivative of
organophosphorus compound 64
Use in agriculture 64
Use rate 64
METAISOSYSTOX
Cases of human poisoning 414
Signs and symptoms 414
METALDEHYDE
Use in snail baits 73
Use- in slug baits 73
Action as attractant and toxicant 73
Formulation with or without
calcium arsenate 73
METEPA
Mutations in barley 584
Mutagenic threshold 598
Use as chemoslcrilant pesticides 598
Testing for mutagenicity 598
Effect on DNA 606
Ethylcncimines 606
METHAM
Carbamates and thiocarbamates 607
May affect DNA 607
METHANE SULFONATE-
BROMOETHYL
Sulfonic acid derivative 584
Mu.itions in higher plants 584
bcti-METHANE SULFONYL
OXYBUTANE
See MYLERAN
METHOMYL
See LANNATE
METHOXYCHLOR
Increase in usage 51
Uses, currently accepted 51
Effectiveness against pests 51
Effect of restricting usage of
persistent pesticides 51
Production and usage,
comparison with DDT 51
Use in fly control 51
Compounds related to DDT 63
Use rates 63
Potable water supply 121
Standards, limits 122
Residues in cow's niilk 140
Effect on phytopbnkton 207
Studies in volunteers 296
Experimental oral exposure,'
humans 301
Safety levels 01 methoxychlor 301
49
-------
CHEMICAL SUBSTANCE ISDEX
Chlorinated hydrocarbon pesticide 313
Acute oral toxicity, LD-50 313
U.S. pesticide production, annual 315
Toxicity to rats 430
Tendency to accumulation
in fat and tissues 430
Effect of carbon tetrachloride
damage to liver, toxicity 430
Eifcct of liver microsomct 430
Estrogenic effects in rats 437
Tumorigenicity testing, results 475
Registered for use on food crops 475
Enzyme induction, measurements
in progress 520
oeta-METHOXYETHYL
METHANr SULFONATE
Sulfonic acid derivative 584
Mutations in higher plants 584
METHYL BROMIDE
Use before World War II 45
Fumigants 65
Use in agriculture 65
Use in public health 65
Use rate 65
Accidents, by industry,
by occupation 154
Fumigants 198
Residue remaining in soil 198
Absorption by plints 198
Control of pests in soil 198
Volatility 198
U.S. pesticide production, annual 315
U.S. pesticide production, 1966 382
Use in agriculture 611
Fumigant 611
3-ME fH YLCHOLANTHRENE
Enzyme induction 518
Effect on toxkity of Guthion 518
Effect on drug metabolism
in rats 554
Piperonyl butoxide effects.
prior treatment with
3-methj kholanthrene 554
METH Vl-DEMETON
Occupational exposure,
morbidity effects 345
Organophosphorous compounds 345
Sysr.emic insecticides 610
Use in apiculture 610
3,4-METHYLENEDIOXY-
C1NNAMIC ACID
Excretion in rats 547
METHYLEUGENOL
Synthetic attractants 75
Use in contiol of fruit flies 75
Use in control of melon flies 75
Use in control of
Mediterranean fruit flies 75
N-METHYL.2-FORMYL
PYR1DINIUM OXIME
See 7.-PAM
METHY1 LINOLATE
Synthetic attractants 75
Use in control of fruit flies 75
Use in control of melon flies 75
Use in control of
Mediterranean fruit flies 75
MtTH* T MERCURIC
HYOROXIDF.
Chromosome aberrations
in higher plants 583
METHYL METHANE
SUIFONATE
Mutations in higher plants 584
Mutations 585
Potent mutagenic compound 595
Testing for mutagenicity 595
l-METHYL-3-NITRO.l-
NTTROSO-GUANIDiNE
Chromosome aberrations in
higher plants 584
Nudeosides 584
N-METHYL-N'-
N1TROSOGUANADINE
Mutations in higher plants 584
METHYL PARATtaON
Use in U.S., use on cotton 47
Organophosphates, phenyl
derivatives 64
U«e rates 64
SO
-------
CHEMICAL SUBSTANCE INDEX
Non-persistent pesticide
Uses
Human exposure
Poisonir.g, in comparison
with parathion
Pc/oonipg cases
104
104
296
307
308
Acute oral toxicity. LD-50 312
Acute dermal toxicity, LD-50 312
U.S. pesticide production, annual 3 IS
U.S. pesticide production. 1966 382
Urine, indicator of exposure 448
May affect DNA 608
!ns:cticides, use in agriculture 610
METHYL ZIMATE
&c ZIRAM
METlKAM
Sti POLYRAM
MEV-NPHOS
See PHOSDRIN
MGK264
Use as pyrethrin syner&ist 65
In combination with carbamates 65
S42
S42
150
Synergists for pyreihroids
Use commercially
MH
See MALEICIIYDRAZIDF
MILO
Mothproofing chemical
M1LOGARD
SeePROPAZINE
MPAFOX
Organophosphate pesticide 360
Demylination of nerve fibers 360
Non-use in U.S. 360
Production of poryneuritis,
humans 413
Non-use in US. 413
Organophosphorus poisoning 416
Production of peripheral neuritis 416
Fluorine containing organic
phosphorus pesticide 419
Damage to nervous system 419
Non-use in U.S. 419
M1REX
Needed knowledge of sample
composition, purity 1 1
Use in fire-ant control 54
Effect on r-hytoplankton 207
Tumorigenicity testing, results 470
Registered for use on food crops 470
Tumorigenicity testing, rating
MITOMYCIN C
Chumo^iTieabtfi
Mutagenk effects
MOBAM
May affect DNA
MOLINATE
Carbamatct
Use in agriculture
Use rates
489
591
591
606
69
69
69
Toxicity to humans 70
Toxicity to warm-blooded anirr Us 70
Persistence in soil 70
MONITOR
Organophosphate 60S
May affect DNA 60S
MONURON
Substituted ureas 69
Absorption through roots 69
Persistenc: in soil 69
Use rate, pteemergence 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
Use rate, soil steriiants 69
Tumorigenicity testing, results 473
Registered for use on food crops 473
Tumorigenicity testing, rating 490
Tumorigenicity testing, results 492
Mutations in barley 584
Organism tested, dose, effect 642
SI
-------
CHEMICAL SUBSTANCL INDEX
Products, producers 651
Application 651
U.S. patent number 651
Chemical name structure 651
Physical properties 651
Product form 651
Oral toxicity, LD-50 651
Testing for increase anomalies 673
MORESTAN
Fungicide 67
Use raw 67
Uses 67
Chlorinated carbamates 364
Dermatitis in workers 364
Occupational exposure 364
May inhibit DNA synthesis 609
MOROCIDE
Miscellaneous fungicides 67
Uses 67
Use rate 67
MORPHINE
In treatment of poisoning 451
Chromosome aberrations in
higher plants 533
MORPHOTHION
Oximes, effect on toxicity 453
MOTOCIL
Chemical structure 557
MYLERAN
Mutations in higher plants 584
Chromosome aberrations in
higher plants 584
MYRISTICIN
Fatty livers, animals 543
Metabolism in mice 543
NABAM
Dithiocarbamate fungicides 66
Use in agriculture 67
Use rates 67
VS. pesticide production, annual 315
U.S. pesticide production. 1966 382
Tumorigcnicity testing, results 475
Registered for use on food crops 475
Oxidation product of nabam,
tumorigcnic in mice 492
Testing for increase anomalies 674
NA1.ED
Use in mosquito control 54
Use by Department of Defense 54
Organophosphorus compounds,
aliphatic derivatives 64
Use rates 64
Use in agriculture 64
Use in mosquito con trol 127
Dermatitis in female
chrysanthemum workers 364
NAPHTHALENE
Use in 20th century 45
Metabolism by house fly
microsome enzymes 555
Lffect of MDP compounds on 555
1-NAPHTHALENE
ACETAMIDE
Tumorigemcity testing, results 474
Registered but not for use
on food crops 474
m-NArTHALENEACETIC
ACID
Auxins 74
Uses 74
Use rate 74
ALPHA-NAPHTHOL
Increase in abnoiniai fetuses 666
NAPTALAM
Phthalamic aud herbicides 69
Preemergent herbicide 69
Use rate 69
Toxicity to humans 69
Toxicity to warm-blooded animals 69
AIanap-3, mutations in barley 584
Organism, dose, effect 643
Products, producers 651
U.S. patents 651
Chemical name, structure 651
52
-------
CHEMICAL SUBSTANCE INDEX
Physical properties 651
Product form 651
Oral toxicity. LD-50 651
Major end uses 651
BETA-NAPTHOXYACETIC
ACID
Auxins 74
Uses 74
Use rate 74
1-NAPHTHYL N-METHYL-
CARBAMATE
See CARBARYL
N-1-NAPHTHYLPHTHALAMIC
ACID
Sec NAPTALAM
2-N/ PTHYLTHIOUREA
SecANTU
NEBIXARINE
Mutations iii higher plants 583
NEMAGON
Halogenated hydrocarbon
nematoctdes 71
Persistence 71
Use rates 71
NIA-10242
Treatment of single oral
LD-50 doses 454
Use of tetraethylaramonium
chloride for treatment
f»f poisoning 454
Carbamate 454
NICOTrNAMIDE
Testing for increase iriomalie* 674
NICOTINE
Pesticides before 1945 44
Discovery of, in 1809 44
Use of tobacco to kill iphids 44
Botanical insecticides,
of lesser importance 63
Use a* pesticide 83
Epidemics of poisoning* 311
Chemical structure of 5S6
NTTRAUN
Dinitroaniline herbicides 70
Use in agricultuie 70
Use rates 70
Persistence 70
Toxicity to humans 70
Toxicity to warm-blooded animals 70
Use in agrculture 610
Herbicide 610
NITROGEN MUSTARD
Mutations in higher plants 583
Chromoso.ne aberrations in
higher plants 583
Mutations 585
Chromosome aberrations 591
Mutagenk effect 591
p-NITROPHENOL
Sec PARAN1TROPHENCL
NITROSOAMJNES
Mutations in higher plants 583
N-NTTROSO-N-MEfHYL
URETHANE
Chromosome aberrations in
higher plants 584
NITROX
See METHYL PARATHION
NORBORMIDE
Rodenticide 72
Toxicity tc rats 72
Toxicity to other
warm-blooded animals 72
Specific toxicant for Norway rat 426
Use as rat poison 426
NOREA
Substituted urea herbicide ' 69
Absorption through roots 69
Persistence in soil 69
Use rates 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
Tumorigentcity testing, results 475
Registered but not for use
on food crops 475
May affect DNA 608
OCTAMETHYLPYRO-
PHOSPHORAMIDE
See SCHRADAN
53
-------
CHEMICAL SUBSTANCE 1NL EX
OCTYL, ROPYI. SULFOXIDE
Insect repellent 75
OMPA
See SCHRADAN
OKDRAM
See MOL1NATE
ORTHOCIDE
Sec CAPTAK
O3THOPHENYLPHENOL
May affect DNA 606
OVEX
Tumorigenicity testing, results 473
Registered for use on food crops 473
Tumorigenicity testing, rating 490
Testing for increase anomalies 674
7-OXABICYCLO (2.2.1)
HEPTANE-2,3-
DICARBOXYL1CACID
See ENDOTHALL
OXYDEMETOMETHYL
See MET/VSYSTOX-R
2-1 AM
Oiganophosphate poisoning,
treatment with 2-PAM 348
Carbamate poisoning, 2-PAM .-nay
produce worse clinical signs 34 S
Antidote, cholinesterase
inhibitors 453
PANOGEN
Organic mercury compounds 66
Use as fungicides for
seed treatment 66
Use in agriculture 66
Use ra.-es 66
May affect DNA t08
PARADICHLOROBENZENE
Use in early 20th century 45
Fumigants 65
Use in agriculture 65
Use for public health 65
Use rate 65
Morbidity effects of
occupational exposure 347
Urine, indicator of exposure 448
Organi- -.r. tested, dose, effects 642
Products, produt •'s 651
Applit Jtion 651
Chemical name, ••tructurr 651
Physical proper res 651
Product form 651
Oral toxicity. Li>50 651
Major end use* 651
PARANITROF.fENOL
Metabolite of organophosphates 347
Renal tubular damage from
orcanophosphates 347
Use of, as indicator of
pari> thion absorption in man 403
Metabolism of parathion. me
of Miitrophenol cxoe'ion
levels 430
Humaris, metabolism of parathion 430
Influence of intcuurrcnt
disease, skin and kidney
pathology 430
Effect of ambient temperature
or. excretion of p-nitrophenol,
humans exposed to parathion 433
Exposure of workers to
parathion 433
Effect of temperature on
excretion of p-nitrophenol 433
Use of urine as indicator
of poisoning 448
Use of urine as indicator
in treatment of parathion
poisoning 448
PARAOXON
Dermal absorption in rabbits 402
Conversion of parathion by
ultraviolet tight 433
Toxicitv 433
PARAQUAT
Herbicides 70
Miscellaneous category 70
Toxicity to mammals 70
Postemergent herbicide 205
Dessicant 205
Toxicity to fish and wildlife 205
Effect of exposure of hands 365
54
-------
CHEMICAL SUBSTANCE INDEX
Effect on fingernails
Injury to lungs
Effect on eyes
Human exposure, effect
on kidney, liver
Absorption from intestine
Lxcretion in urine
Symptoms of poisoning
Poisoning, effect on heart
Esophagcal casts, humans
Fatal cases, effects
L'ffect on fingernails
Personal indicators of
over exposure
365 Disposal of containers.
rinse water
159
Effect on DNA
Effect on plants
Use in agriculture
Herbicide
PARATHION
Absorption through skin
Humans, adverse effects on
Non-persistent pesticide
l)ses
Dermal, respiratory exposure,
humans
Atmospheric contamination
Ground waters
Potable water supply
Standards, limits
Water, contamination of
Daily intake, FAO-WHO
Leaching from soil by water
Accidents, by industry,
by occupation
Exposure of spray men
Spraying, exposure
Accidents, poisonings, deaths
607
607
610
610
81
81
104
104
112
114
116
121
122
124
137
144
154
155
156
157
368
368
370
370
370
370
371
373
373
405
446
607
607
610
610
81
81
104
104
112
114
116
121
122
124
137
144
154
155
156
157
Inhibition of cholinester-se
enzymes of ncuromuscular
system
Uses
Toxicity
Controlled human exposure
Acute poisonings, epidemiology
Poisoning, in comparison
with methyl paralhion
Dermal toxicity
Human ingestion, cliildicn
Epidemics of poisoning
Acute oral toxicity. LD-50
Acute dermal toxicity, LD-50
Epidemiology of poisoning cases
U.S. pesticide production, annual
Morbidity effects of
occupational exposure
Health hazards
Exposure of population
Peripheral neuropathy
Scnsitizer, humans
Occupational dermatitis
Occupational^ related
skin conditions
Hematological disorders
Dysuria, human exposure
VS. pesticide production. 1966
Paranitrophenol in urine.
major metabolite of
para th ion
Blood dyscrasias
Skin, decontamination of
Cutaneous metabolism
Dermal absorption in rabbits
206
263
263
296
306
307
307
308
311
312
312
314
315
347
347
352
360
364
364
366
372
373
382
388
388
400
401
402
55
-------
CHEMICAL SUBSTANCE INDEX
Respiratory exposure
Excretion in man
Penetration of
Sample skin matrix
Rats, treatment of.
effect on cholinestcrasc
Behavioral effects,
suspected chemicals
Behavioral changes
Species susceptibility
Death in children
Sex hormones, effect on
susceptibility to
parathion
Metabolism in mar.
Excretion of p-nitroplicnol
in urine
Temperature, effect on toxicity
Humans, temperature.
effect on toxicity
Ultraviolet tight, effect on
Conversion to paraoxon
Toxicity of paraoxon
Dermal vj inhalation
contamination
Urine, indicate; of exposure
TEA chloride, use as an
antago- ist
Prior feeding of rats with
aldrin, chlordanc or
lindane, effect on
poisoning
Effect of diet on
Temperature, effect on
toxicity, rats
May affect DNA
Insecticides, use in agriculture
Organism tested, dose, effects
402
402
403
405
411
413
417
427
428
429
430
430
432
433
433
433
433
445
448
454
524
532
533
608
610
643
Products, producers
Application
U.S. patent number
Chemical name, structure
Physical properties
Product form
Oral toxicity, LD-50
Major end uses
Tmtogcnic in chick embryo
P.SRISGREEN
Use of as pesticide in 1865
Inorganic compounds
Use against potato beetle
Restriction of use
Toxicity to humans
Persistence
Mosquito control
Application of pellets
Us* of dursban, comparison
with Paris Green
Economy of usage
PARZATE
See NABAM
PBA
Se? BENZAC
PCB
Error in analysis of DDT,
due to presence of PCB
Spread in environment since 1929
Analytical errors in analysis
of chlorinated hydrocarbons
Noted in British since 1966
Identified in fish.
wildlife and environment
Contained in human milk
Results of interpretation of data
Possible effects of storage
of samples in plastic
containers
Human pesticide residues
Interpretation of results of
human pesticide residues
PCNB
Needed knowledge of sample
composition purity
Chlorine-containing fungicides
Use in agriculture
652
652
652
652
652
652
652
652
665
45
45
45
62
62
62
127
127
127
127
257
257
257
257
257
258
258
258
319
319
11
67
67
56
-------
CHEMICAL SUBSTANCE INDEX
Use rates
Uiine, indicatoi of exposure
Tumorigenicity testing, results
Registered but not for use
on food crops
Tumoiigenicity testing, rating
Recommendation for tcratogenicity
testing 658
Production of increased
renal agenesis, mice
Production of abnormal fetuses
Testing for increase anomalies
PCP
Miscellaneous insecticide
compounds
Use in preventing
termite damage
Chlorine-containing fungicides
Use in agriculture
Use rates
Substituted phenol herbicides
Use foi weed control
Use as preemergence herbicides
Persist :nce in soil
Translocation in plants
Toxicity to mammals
Herbicides
Residues in fooos
Environmental contamination
Epidemics of poisoning
Chlorinated phenols
Dermatitis in industry
Excretion in urine
Chlorinated phenols
Neuritis from treating
furniture
Mixtures of
Qdorinated phenols
IrriUtio.n of respiratory tract
Analysis of blood; diagnosis
of intoxication
Therapy
67
448
470
470
489
Atropine. use in poisoning
treatment
Poisoning symptoms, resembling
cltolinesterase inhibitors
Tumorigenicity testing, rating
May affect DNA
Use in agriculture
Fungicide
450
450
489
606
610
610
666
666
673
65
Organism tested, dose, effect 642
Products, producers 652
Application 652
Chemical name, stricture 652
Physical properties 652
Product for.n 652
Oral toxicity, LD-50 652
Major end usej 652
65
67
67
67
69
69
69
69
69
69
136
136
136
311
364
364
364
367
367
367
370
370
448
450
PEBULATE
See TILLAM
PENICILLAMINE
Antidote for htavy metal
poisoning
Chrlating agent for copper, lead
and possibly mercury
PENPHENE
Thiophene nematocides
Use for pest control on tobacco
Fumigant action
Use rates
Precautions before planting
PENTACHLOROPHENOL
See PCP
PENTA (PCP)
See PENTACHLOROPHENOL
PERTHANE
Acute oral toxicity, LD-50
Effects on respiratory system
Thermal decomposition products
Irritation to respiratory tract
Tumorigenicity testing, results
Registered for use on food crops
Tumorigenicity testing, rating
Testing for increase anomalies
452
452
71
71
71
71
71
313
369
369
369
473
473
489
674
57
-------
CHEMICAL SUBSTANCE INDEX
1'ETROLEUM
Pesticides before 1945 45
Use in insecticides in
18th century 45
Toxicity to plants 45
Toxicity to insects 45
Use as larvicides for mosquitoes 45
Poisoning in children from
petroleum products 157
Human volunteers, DDT in
petroleum, skin exposure 297
PHALTAN
SeeFOLPET
PHENOBARBITAL
Effect on DDT residues, humans 323
Histologies! changes 434
Enzyme induction 434
Effect on DDE blood levels,
humans 436
Use in controlling convulsions 451
Pretreatmcnt, effect on organic
phosphate toxicity 518
Effect on dicldrin 528
Enzyme induction 528
Effect OD dicldrin storage 528
Enzyme induction 529
Effect on chlorinated hydrocarbon
levels in humans 529
Effect on DDE blood levels,
humans 529
Antidote for acute DDT
poisonings 529
Effect on piperonyl butoxide 555
PKENOTHIAZINE
Use in treatment of phosdrin
and parathion poisoning 41 /
Potentiation of organophosphorous
compounds 417
Tumorigenicity testing, results 475
Registered for use on food crops 475
Possible inhibition of DNA
synthesis 609
PHENYI. MERCURIC
ACETATE
Organic mercury compounds 66
Use as fungicides for seed
treatment 66
Use in agriculture 66
Use rates 66
Metal-organic compounds 68
Use in weed control 68
Use in crabgrass control 68
Tumorigenicity ttsting, results 475
Registered but not for use on
food crops 475
Mercurials 664
Fetal malformations in mice 664
PHENYl MERCURIC
HYDROXIDE
Mutations in higher plants 583
Chromosome aberrations in
higher plants 583
PHENYTOIN
See DiPHENYLHYDANTOIN
PHOKATfi
Organic phosphate compounds 60
Plant systemic insecticides 60
Organophosphorous compounds 64
Use rates 64
Acute oral toxicity. LD-50 312
Acute dermattoxlcily, LD-50 312
Occupational^ related skin
conditions 366
May affect DNA 608
Systemic insecticide 610
Use in agriculture 610
PHOSDRIN
Organophosphorous compounds,
aliphatic derivatives 64
Use rate 64
Metabolism of pesticides
by plants 133
Systemic insecticides 133
Application, before harvest 133
Toxicity to crab larvae 209
58
-------
CHEMICAL SUBSTANCE INDEX
Pesticides poisonings
Epidemics of poisoning
308
310
PHYTONADIONE
See VITAMIN Kl
Acute orai toxicity, LD-50
Acute dermal toxicity, LD-50
Organophosphatcs
Health hazards
Toxicity
Routes of exposure
Direct cholinesterasc
inhibitors
Organophosphorous compounds
Topical effects
Occupationally related
skin conditions
Organophosphorous compounds
Contamination of eyes
Human poisoning by phosdrin
and/or p~:athion
Acute oral toxicity to rats
Toxicity to weanling rats
Toxicity 10 adult rats
PHOSPHAMIDON
Acute oral toxicity, LD-50
Acute dermal toxicity, LD-50
Mutat-'ons in barley
Organophosphate
May affect DNA
Systemic insecticide
Organism tested, dose, effects
Products, producers
Application
U.S. patent number
Chemical name, structure
Physical properties
Product form
Oral toxicity, LD-SO
Major end uses
PHOSPHON
Growth retardants
Uses
PHYGON
See DICHLONE
312
312
347
M7
347
347
364
364
3o4
366
367
367
417
427
427
427
3i2
312
584
608
608
610
642
6S3
653
653
653
653
653
653
653
74
74
PICLORAM
Herbicides, miscet'-inccu;,
category
Toxicity
Use in agriculture
Use in industry
Degradation in soils
Use in agriculture
Herbicide
PIPERONAL
MDP synergists, prepared
from pipcronal
Use of materials, limitations
Excretion by rat jits
Oxidation -
-------
CHEMICAL SUBSTANCE INDEX
Malignant tumors of lymphatic
system 544
Cocarcinogenic potential 544
-•-. In aerosol spray, animal
experiment 545
Effect with freon administration 545
Synergistic toxicity, Freons,
other chemicals 546
Effect on hexobarbital
sleeping time, rats 546
Excretion by dogs 547
Excretion in rats 547
Metabolism, excretion in bile 548
Metabolism of 549
Tentative metabolic fate
in mam-nab 552
Inhibitor of Jrug
metabolism, Mts 555
Effect of phenobaibital or
3-methylcholanthrene on 556
Chemical structure 557
Pyrethioid sy ncrgists 611
Household applications 611
Carbuyl phis pipetonyl
butoxide, effects 666
No significant increase in
anomalies, as tested 674
PffERONYL SULFOXIDE
Tumorigenicity testing, results 473
Registered for use on food oops 473
Tumorigenicity testing, rating 492
PfPERONYUCACID
Metabolite in urine, dogs 547
' Metabolites of chemicals 547
PTVAL
Anticoagulant rodenticides 72
Uses 72
Usente 72
2-PTVALYL-l>
INDANEDIONF
SecPIVAL
PLANAVIN
See NITRALIN
PLANOnX
Tumorigenicity testing, results 475
Registered for use on food crops 475
PMA
See PHENYLMERCURIC
ACETATE
POLYCHLORINATED
BIPHENYLS
SeePCB
POLYRAM
Dithiocerbamate fungicides 66
Uses 66
Use rate 66
Stability 66
POTASSIUM. BIS
(2-HYDROXYETHYL)
DrrmOCARBAMATE
Tumorigenicity testing, rating 491
POTASSIUM CYANATE
SeeKOCN
PPJNCEP
See SIMAZINE
PROGESTERONE
Enzyme activity, liver, rats 428
PROMETONE
Heterocyclic nitrogen dcrr dves 69
Toxicity to mammals 69
Uses 69
Use rate 69
Persistence 69
PROPACHLOR
Miscellaneous herbicide 70
Toxicity 70
Uses 70
Oarbamates and thiocarbamates 607
May affect DNA 607
Herbicide 610
Use in agriculture 610
PROPAN1L
Amide derivatives 70
Herbicides 70
Persistence in soil 70
Toxicity 70
60
-------
CHEMICAL SUBSTANCE INDEX
PROPAZINE
Htterocyclic nitrogen derivatives
Herbicide
Toxicity to mammals
Persistence in soil
Uses
Use rate
Tumorigenicity testing, results
Registered for use on food crops
Testing for increase anomalies
PROPHAM
Tumorigenicity testing, results
Registered but not for use on
food crops
Tumorigenicity testing, rating
Organism tested, dose, effects
Products, producers
Application
Qiemical name, structure
Physical properties
Product form
Oral toxicity, LD-SO
Major end uses
Recommended for further
tetatogenicity testing
Production of abnormal fetuses
Testing for increase anomalies
beta-PROPIOLACTONE
Chromosome aberrations in
higher plants
n-PROPYL ISOMER
Tumorigenicity testing, rating
PROPYLMETHANESULFONATE
Mutations in higher plants
Mutations
Potent mutagenic compound
PRUSSICACID
See HYDROGEN CYANIDE
PURINERIBOSIDE
Chromosome aberrations in
mammalian cells in tissue
culture
PYRAMIN
69
69
69
69
69
69
475
475
674
473
473
491
643
653
653
653
653
653
653
653
658
666
673
Miscellaneous herbicides
Toxicity
U**s
PYRAZON
See PYRAMIN
PYRETHRIN
Formulation varieties
Synerfist added
Tumorigenicity testing, results
Registered for use on food crops
PYRETHRIN I
Metabolism of
Chemical structure of
PYRETHRUM
Pesticides before 1945
Attempt to synthesize, 1920
Use against anopheles gambiae
Botanical insecticides
Mixed with sodium fluoride
Synergists to enhance action
Use of sy nergist with
Combined effects, with DDT
70
70
70
62
62
474
474
555
556
44
45
46
83
151
526
541
584
492
584
585
S95
S91
and piperonyl butoxide,
rats, liver 544
QUELETOX
A formulation of-Baytex
insecticid- 73
Use in bird control 73
QUINOLINOLATE
Metal organic fungicides 66
Use for treatment of equipment 66
Use to prevent rot and mildew 66
Use rate 66
RATICATE
See NORBORMIDE
RED SQUILL
History of use 44
World War II supply problems 45
61
-------
CHEMICAL SUBSTANCE INDEX
Botanical rodcnticide 72
Toxicity to other
warm-blooded animals 72
Use rate 72
Toxicity to cats 214
9-beta-D-RIBOFURANO-
SYLPURINE
See NEBULA RINE
RODANNITROB ENZENE
Allergic dermatitis in
agriculture workers 399
RONNEL
Organic phosphate phcnyl
derivative 64
Use rate 64
Air transport of, dust storm 113
Phosp.ate ester pesticide 312
Acute oral LO-SO toxkity value 312
ROTENONE
Plant materials containing,
used in 1848 44
Botanical insecticide 62
Kills by inhibiting
oxygen utilization by insect 63
Toxicity to animals 63
Swine, toxicity to 63
Uses 63
Plant extract as pesticide 83
Water treatment processes,
removal of 122
Use as piscicide for fish 213
Effects on aquatic, insect life 213
Toxicity to fish 426
Toxicity to certain mammals 426
Toxicity to birds 426
SynergisU used to enhance
toxicity of 541
Chemical structure of 556
ROTHANE
SeeTDE
RUELENE
Organophosphate 608
May affect DNA 608
RYANIA
Botanical insecticide 63
SABADILLA
History of use 44
Use as louse powders by
South American natives 44
Botanical insecticide 63
SACCHARIN
Chromosome aberrations in
higher plants 584
SAFROLE
Natural product 542
Used in preparation of
pesticidal syncrgists 542
Annual production per year 542
Effect on bile acid or
cholic acid concentration in
male rats after injection 543
Rat hcpatocarcinogen 543
Hepatic damage and nodular
degeneration, led with a
riboflavin-deficient
diet, rats 543
F brosis and deposits of
ccroid pigment when fed
to rats 543
Liver tumors in mice 544
Metabolites in rat bile and
urine after intravenous
administration 548
Analysis for metabolites 548
Metabolic pathway in mice 548
Metabolic pathway in houscflies 549
SANEX
Mothproofing product used
in dry cleaning 150
Contains DDT ISO
Exposure of employees
and customers to DDT ISO
SANITONE
Mothproofing product used
in dry cleaning 150
62
-------
CHEMICAL SUBSTANCE INDEX
Contains 100% DDT 150
Exposure of cmplo) ees
and customers to DDT ISO
SARIN
Toxkity to monkeys at
different environmental
temperature 432
Toxicity to hibernating and
non-hibernating hamsters 432
Toxkity to monkeys, effect
of temperature 533
SAROLEX
Organic phosphate nematicide 71
DUzinon containing product 71
Use rate 71
Uses 71
SCHRADAN
Controlled human exposure 296
Contamination of eye 367
Signs and symptoms of eye
exposure 367
Acute oral toxicity 427
Organophosphorous insecticides 427
Toxicity to adult rats 427
Toxicity to weanling rats 427
Alteration of toxicity
by enzyme induction 518
Toxicity in nvce 518
Chemical structure of 556
SCOPOLAMINE
Chromosome aberrations in
higher plants 583
SECONAL
Behavioral effect of 418
Effect on brain 418
Effect on continuous
performance test 418
SELENIUM, DIETHYL-
DITHIOCARBAMATE
Tumongenicity testing, ra ting 491
SELENIUM DITH1O-
CARBAMATE
Tumorigenicity testing, rating 491
SEMAN
Effect of DMSO on skin
penetration 403
SEMESAN
Organic mercury fungicide 66
Use rate 6C
Uses 66
,S£SAME OIL
Source of methylenedioxyphenyl
(MDP) derivatives 543
Food use 543
Lipid vehicle for other agents
in cancer research 543
Co-carcinogenic activity in
sarcoma production 543
Sesamin obtained from 543
Heated oil, effect on
subcutaneous injection, mice 543
Co-cr.rcinogcnic fractions of 543
SESAMFX
Synergist with carbamate
insecticides 65
Synergist 546
Effect on hexobarbital
deeping time, mice 546
SESAMIN
Isolstcd from sesame oil 543
Methylenedioxyphenyl (MDP)
derivative 543
Co-carcinogenic with
3,4-benzpyrcne (bcnzo [a]
pyrene) 543
SESONE
Phcnoxy herbicide 68
Use rate 68
Uses 68
SEVIN
See CARBARYL
SIDURON
Sec TUPERSAN
SIGLURE
Insect attractant, synthetic 75
Use in control of fruit flies
and melon flies 75
SILVEX
Phcnox> herbicide 68
Persistence in soil 68
Toxicity to man and other
animals 68
Use rate 68
Uses 68
63
-------
CHEUICAL SUBSTAjtCE INDEX
Synthetic auxin for
agricultural use
Use rate
Uses
Water concentrations
Analysis of streams
74
74
74
128
128
Urine indicator of exposure,
human 448
SIMAZINE
Heterocycltc nitrogen derivative 69
Uses 69
Use rate 69
Toxicity to mammals 69
Persistence in soil 69
Urine, indicator of exposure 448
Tumorigenicity testing, results 47S
Registered for use on food crops 475
Tumorigenicity testing, rating 490
Mutations in barley 584
Organism tested, dose, effect 643
Taken up by plant roots 645
Products, producers 653
Application 653
U.S. patent number 653
Chemical name, structure 653
Physical properties 653
Product forms 653
Oral toxicity, LD-50 653
Major end uses 653
SINBAR
SeeTERBACIL
SIX-TWELVE (6-12)
See ETHYL HEXANEDIOL
SMDS
SeeVAPAM
SODIUM ARSEN1TE
Use as insecticide, weed killer 45
Inorganic herbicides 67
Use rates 68
Plant growth regulators 205
Rodenticides, hazard to humans 214
Poisoning, humans 362
SODIUM BORATE
Inorganic herbicides 67
Use rates 68
SODIUM CHLOROPHENYL-
PHENATE
Chlorophenols 373
Occupational exposure.
workers effects on 373
SDDIUM.DIETHYL
DITHIOCARBAMATE
Tumorigenicity testing, rating 491
SODIUM ETHYLENE(bij)
DITHIOCARBAMATE
Tumorigenicity testing, rating 491
SODIUM FLUOALUMINATE
Metallic salt< 45
Persistence in soil? 45
Use as pesticide 45
SODIUM FLUORIDE
Insecticides for household use 151
Use with pyrethrum 151
SODIUM FLUOROACETAft
See COMPOUND 1080
SODIUM FLUOROSILICATE
Inorganic rodenticides 72
In combination with zinc cyanide 72
SODIUM ORTHOPHENYL-
PHENATE
Dusts containing, nasal and
bronchial irritation 370
SODIUM SULFATE
Treatment of poisoning 450
Treatment of poisoning 451
i
SPERGON
See CHLORANIL
STAM
See PROPANIL
STREPTOMYCIN
See AGRIMYCIN
STREPTONIGRIN
Chromosome aberrations in
higher plants 583
64
-------
CHEMICAL SUBSTANCE INDEX
STROtANE
Residues in meat, cow's milk
Tumorigenicity testing, results
Registered for use on food crops
Tumorigenicity testing, rating
STRYCHNINE
Botanical rodenticides
Uses
Rodenticides
Hazards to humans,
domestic animals
SUGARYL
Chromosome aberrations in
higher plants
o-SULFOBENZOICIMIDE
See SACCHARIN
SULFUR
Lime sulfur washes, 1886
Lime sulfur sprays,
resistance to
Inorganic insecticides,
sulfur derivatives
Inorganic fungicides
Accidents, by industry,
by occupation
Fungicides, production, volume
Occupational^ related skin
conditions
Lime-sulfur mixtures, fungicides
Dermatitis, conjunctivitis
Pentavalent sulfur, plus
chlorine atoms,
non-tuntorigenic
Sulfur mustard, chromosome
effects in plants
Unknown mechanism of action
SULFUR MUSTARD
Chromosome aberrations in
higher plants
SUMITHION
140
470
470
489
72
72
714
Alt
214
cot
583
45
59
62
66
154
202
366
368
«Q
JO7
490
583
604
583
Grasshopper control
Trial studier with; poor
control Li practice
SUTAN
Carbamates
Uses
Use rate
Persistence m soil
Toxicity to humans
Toxicity to v arm-Wooded animals
SYSTOX
Sec DEMETON
2.4,5-T
Needed knowledge of sample
composition, purity
Phenoxy heit.icido
Uses
Persistence in soil
Toxicity to humans
Toxicity to f nimals
Auxins
Uses
Use rates
Drift in storms
Potable water supply
Standards, limits
Water concentrations
Use, domestic, pounds
Disappearance in soil
Persistence
Study of soil microorganisms
after application
Chloracne
US. pesticidf production, 1966
Urine, indicator of exposure
Judged not positive
for tumoiigenichy
Registered but not for use
on food crops
Structure-activity relations
Hormone (auxin) analogs
91
91
69
69
69
70
70
70
11
68
68
68
68
68
74
74
74
113
122
122
128
147
203
204
204
365
382
448
475
475
604
604
65
-------
CHEMICAL SUBSTANCE INDEX
Us: in agriculture, herbicides 610
Postemergcnce herbicides 610
Organism tested, dose, effect 643
Products, producers 653
Application 653
Chemical name, structure 653
Physical properties 653
Product forms 653
Oral toxicity, LD-SO 653
Major end uses 653
Teratogenic, restrict usage 658
Tcratogcnic 665
Eflects in rats 666
Increase in abnormal fetuses 666
2,3,6-TBA
See TRYSBEN
TCA
Sec TRICHLOROACETIC
ACID
TCTP
Sec PENPHENE
TDE
Diphcnyl aliphatic
chlorinated hydrocarbon 63
Used as insecticide and miticids 63
Use rate 63
Acceptable daily intake,
FAO-WHO 137
Expended dietary intake
(1965-1968) 137
Analytical interference by
Norwegian cod liver oil,
gas chronvtography 257
US. pesticide production, annual 315
TEDION
Testing for increase anomalies 674
TULLURfUM. D1ETHYL
DITHIOCARBAMATE
Turr.origcnicity tc sting, rating 491
TELODRIN
Effects on industrial workers 409
Occupational exposure 409
TF-LONE
Halogenated hydrocjrbon
nematocidcs 71
Persistence 71
Toxicity to humans 71
Use as soil nematocides 71
Toxicity to plants 71
Use rates 71
TELVAR
Sec MONURON
TEMIK
Human intoxication 362
May affect DNA 607
Carbamates and thiocarbamatcs 607
TtNORAN
See CHLOROXURON
TEPA
Mutagenic threshold, in mice 598
Effect on DNA 606
TEPP
Aerial application of 110
Conditions, effect on
humans and wildlife 110
Precautions for spraying 110
Metabolism by plants 133
Preharvest interval 133
Exposure of workers 156
Acute oral toxicity, LD-SO 312
Acute dermal toxicity, LD-50 312
Occupational exposure, workers 347
Organophosphates 347
Health hazards 347
Toxicity 347
Routes ci absorption 347
Cholincsterase inhibition 347
Organophosphorus compounds 364
Direct cholinesterase inhibitors 364
Effects of exposure 364
Dermatitis 364
Organophosphorus compounds 367
Effects on eye 367
Bronchoconstriction 369
66
-------
CHEMICAL SUBSTANCE INDEX
Direct cholinestcrase inhibitors 406
Effects on eyes 406
TERBACIL
Herbicides, miscellaneous
category 70
Toxicity 70
Use in agriculture 70
Use in industry 70
May affect DNA 609
Conversion to epoxides 609
TERRACHLOR
SeePCNB
TERRAZOLE
CMorinc-containing
fungicides 67
Use rate 67
Uses 67
1,1,2,2-TETRACHLOSO-
U-DIFI.UOROETHANE
SceFRFONIia
TETRACHLORETHYLENE
Effect on EEC 451
EEC similar to chlorinated
hydrocarbon insecticides 451
TETRACHLOROMETHYLENE
DIOXYBENZENE
Metabolism in microsomal
preparations 548
TETRACHLOROTHIOPHENE
See PENPHENE
TETRADIFON
Tumorigenicity testing, results 475
Registered for use on food crops 475
Tumorigenicity testing, rating 490
TETRAETHYLAMMONIUM
CHLORIDE
Use in treatment of carbamate
poisoning, mice 454
TETRAETHYLPYRO-
PHOSPHATE
SeeTEPP
U.J.9-TETRAMETHYL-
URIC ACID
Purinc 584
Chromosome aberrations in
higher plants 584
THALIDOMIDE
Need for s; stem to recognize
teratogrnic agents 601
Disaster, need for
teratogt-nicity testing 658
Tcratogenfcity of 659
Pregnant women.
effects children 659
Malformat.: s produced by 661
THALLIUM SI LFATE
Salts of, use as pesticides 45
Inorganic rodenticides 72
Use rates 72
Use in starting control 73
Restricted uses 73
Poisonous properties 73
Cumulation 73
Use as insecticide 363
Use as rodcnticide 363
Poisoning it children in U.S. 363
Hair loss, chronic poisoning 365
THANITE
Fumigant 65
Use in agriculture 65
Use in public health 65
Use rate 65
Use in fly sprays 65
THIMET
Sec PHORATE
2,2-THIOBIS
(4,6-DICHLOROPHENOL)
Tumorigenicity testing, rating 489
thio-TEPA
Effect on DNA 606
Ethytenetmincs 606
THIODAN
Acute oral toxicity, LD-50 313
Acute dermal toxicity, LD-50 313
Chlorinated hydrocarbon
pesticides 313
TH1OMETON
Morbidity effects,
occupational exposure 347
67
-------
CHEMICAL SUBSTANCE INDEX
THIRAM
Dithiocarbamate fungicides
Psradichlorobenzene.
66 use to control mold
Uses
Use rates
Use in bird control
Tumorigenicity testing, results
67
67
73
475
TOCP
See TRIORTHOCRESYL
PHOSPHATE
TORPON
See PICLORAM
Registered for use on food crops 475
May affect DNA
607
651
TOXAPHENE
Use of, with decreased DDT usage 9
Teratogeiu'city in hamsters
Non-teratogenicity, results
Testing for increase anomalies
TILLAM-6-E
Carbamates
Use as herbicide
Use rates
Preemergence herbicide
Persistence in soil
Toxicity to humans
Toxicity to warm-blooded animals
Tumorigcnicity testing, results
Registered for use on food crops
Tumorigcnicity testing, rating
TOBACCO
Pesticides before 1945
Use in France to kill
aphids, 1763
Agricultural crops,
pest control economics
Penphene, use to control
nematode pests
Insecticide usage, crops
Pests, use of DDT. BHC,
( cyclodfenrs to control
Losses due to insects
Development of resistant plants
Light traps, insect control
Acrytonitrile, use as
f umigant for stored crops
Ferbam, use to control
fungus diseases
665
665
673
69
69
69
69
69
69
69
475
475
491
44
44
58
71
84
89
89
162
166 •
645
649
Toxicity to fish
Recommended decrease usage
next 2 years
Us?.ge, Dept. of Agriculture
survey
CHorinated aryl hydrocarbons
Ur« in agriculture
Vie in controlling
undesirable fish
UK on crops in the world
1
Rice crops
Use to control cutworms
Oilseeds
Us*1 in foreign countries.
insect control
Cyclodiene organochlorines
Spraying field, drift, residue
Atmospheric contamination by
pesticides
In lakes, effect on
Gsh population
Limits, potable water supply
Wster treatment processes
tor removing toxaphene
Removal of toxaphene at
municipal water plant
Fed to cattle, residues in fat
Concentration in cow's mik
Spraying of cattle, residues
in tissues, milk
18
26
47
63
63
73
84
85
85
90
90
104
109
114
119
122
122
123
139
140
140
-------
CHEMICAL SUBSTANCE INDEX
Recommended decrease usage
next 2 years 180
Effect on phytophnkton 207
Effect on crab larvae 209
Effect on mortality
of fish-eating birds 211
Use as piscicide to control
carp, catfish 213
Persistence 213
Epidemics of poisoning
by pesticides 311
Acute oral toxicity 313
Acute dermal toxicity 313
Chlorinated hydrocarbon
pesticides 313
U S. pesticide production, annual 31S
Effect on excitability
of nervous system 360
Reports of occupationally
related skin conditions 366
VS. pesticide production 382
liver changes in rats 43S
Effect on microsoma! enzymes 519
VS. sales, use in agriculture 610
TOXOGONIN
Use in Europe 453
Antagonism of cholinesterase
inhibitors 453
Mechanism of action 453
TREFLAN
See TRIFLURALIN
TRIBUTYRIN
Inhibition of enzymes by
organophosphates 513
TRICHLORACETIC ACID
Aliphatic acid herbicides 69
Uses 69
Toxicity to humans 69
Toxicity to warm-blooded animals 69
Health hazard, discussion 69
TRICHLORFON
Organophosphorus compounds,
aliphatic derivatives 64
Use rate 64
Use in agriculture 64
Toxicity to rats 427
Effect of age 427
l,l.l-TRIC»LORO-2,2-
bis(p
-------
CHEMICAL SUBSTANCE INDEX
Use in control of melon flier 75
Use in control of
Mediterranean fruit fly 75
U.7-TRIMETHYL
XANTHINE
See CAFFEINE
TRIORTHOCRESYL
PHOSPHATE
Neuronal lesions, polyneuritis 413
Delayed neurutoxitiiy 424
Production in chickens, calves 424
TRIPHENYLTIN ACETATE
Tumorigenicity testing 474
Not registered as pesticide 474
TRIPHENYLTIN HYDROXIDE
Registered for use on food crops 474
Registered for use on
non-food items 474
Pesticide 474
Not tested for carcinogenicity 474
TR1PRUF
Mothproofing chemical 150
TRTTHION
Acute oral toxicity, LD-50 312
Acute dermal toxicity, LD-50 312
Occupational]/ related
skin conditions 366
Occupational exposure,
suspected chemicals ' 413
Effect on rats, weanling vs adult 427
Organophosphates 665
Cholinesterase inhibitors 665
Teratogenic to chick embryos 665
TROPITAL
Preparation of 542
Effect on bDe acids and
cholesterol levels, rats 543
Effect on hexobarbital
metabolism, sleeping time, rats 546
Metabolism of
Metabolism of
548
549
Tentative metabolic fate of
in mammals 553
TRYi'AN BLUE
Testing for increase in
abnormalities 669
Increase in anomalies, mice 670
TRYSBEN
Benzoic acid herbicides 68
Persistence in soil 68
Toxicity to mammals 68
Use in agriculture 68
Use rates 68
May affect DNA 606
TUPERSAN
Substituted ureas 69
Absorption through root system 69
Persistence in soil 69
Toxicity to warm-blooded animals 69
Toxicity to fish 69
Use rates 69
TURPENTINE
Pesticides before 1945 45
Use in 18th century 45
UC 10854
Giemical structure of 557
URETHAN
See ETHYL CARBAMATE
VALONE
Anticoagulant rodenticides 72
Use, precautions 72
Properties 72
VANCIDE BL
Tumorigenicity testing, results 473
Registered but not for use
on food crops < 473
VANCIDE PB
Tumorigenicity testing, rating 489
VAPAM
Dithiocarbamate fungicides 66
Use in agriculture 66
Use rates 66
Stability 67
Control of target organism 67
Effect on DNA, possible 607
70
-------
CHEMICAL SUBSTANCE INDEX
VAPONA
See DICHLORVOS
VEGEDEX
Carbamales
Use as herbicides
Use rate
Persistence in soil
Toxicity to humans
Toxicity to warm-blooded animals
VERNAM
Caibamaies
Use as herbicides
Use in agriculture
Use rate
Persistence in soil
Toxicity to humans
Toxicity to warm-blooded animals
VERNOLATE
See VERNAM
VITAMIN Kl
Antidote for indancdione
derivatives
VORLEX
Cyanate ncmatocides
Soil furrigant
Formulation
Use rate
Precautions for planting
WARFARIN
Anticoagulant rodenticides
Properties
Uses
Poisoning cases, human
Epidemics of poisoning
Temperature, effect on toxicity
XYLENE
Behavioral effects of solvent
Effects of intoxication
YELLOW PHOSPHORUS
Miscellaneous pesticides
Ingestion, poisoning signs
and symptoms
ZEATIN
Cytokinins
69
69
70
70
70
70
69
69
69
70
70
70
70
451
71
71
71
71
71
72
72
72
158
311
432
417
417
371
371
74
Uses
Use rate
ZECTRAN
Carbamate insecticides
Uses
Use rate
Toxicity to bud worm, in
comparison with DDT
Effect of sunlight on
Urine, indicator of exposure
TEAC, atropine, treatment
of poisoning
Tumorigenicity esting, results
Registered but i>ot for use on
food crops
Tumorigenicity testing, rating
Testing for increase anomalies
ZERLATE
Sec ZIRAM
ZINC
Metallic salts, use as
pesticides
Inorganic rodenticides,
zinc phosphide
Fungicides, heavy metals
Heavy metal derivatives.
treatment of poisoning
ZINC, DIETHYL
DITHIOCARBAMATE
Tumorigenicity testing, rating
ZINC DITHIOCAPBAMATE
Tumorigenicity testing, rating
ZINC ETHYLENE ibis)
DITHIOCARBAMATE
Tumorigenicity testing, rating
ZINC PHOSPHIDE
Inorganic rodenticides
Uses
Rodenticides
Hazard to humans, domestic
animals
74
74
65
65
65
111
111
448
454
473
473
491
673
45
71
202
451
491
491
491
72
72
214
214
71
-------
CHEMICAL SUBSTANCE INDEX
ZINEB
Dithtocaibamate fungicides 66
Uses 66
Use rates 66
Stability 66
U.S. pesticide production, annual 315
U.S. pesticide production, 1966 382
Tumorigenicity testing, results 474
Registered for use on food crops 474
ZIRAM
Dithiocarbate fungicides 66
Use in agriculture 66
Use rates 66
Stability 66
Control of target organisms 66
Dithiocarbamates 364
Dermatitis 364
Occupational exposure, effects 369
Respiratory irritation, humans 369
Dithiocarbamates 369
Tumorigenicity testing, results 475
Registered for use on food crops 475
May affect DNA 606
ZOXAZOLAMINE
Effect of piperonyl butoxide
on paralysis time, mice 546
72
-------
SUBJECT INDEX
Subject Page
ABORTION
Abortion, spontaneous 570
Chromosome aberrations 570
Mutation induction by seed
treatment 576
Measurement of responses to
mutagen treatment, pollen
abortion 576
Pollen abortion in mature
flowers 578
Abortions, captan, animals 664
Chlorinated hydrocarbons 674
Abortion, spontaneous, humans 675
Discussion of conclusion of
results 675
ABSORPTION
Study of, in man 33
Metal salts, absorption from
•oil by plants 45
Stomach poison*, absorption
from digestive system 61
Chemical repeUuits, loss by
absorption through skin 75
Modes of entry of pesticides
into body, skin absorption 112
Analysis of 2.4-D in water
samples activated by
carbon absorption 126
Persistent pesticides, toxic
by skin absorption 135
Paratrdon exposure, humans,
absorption from skin 155
Subject Page
Pesticide exposure, humans,
absorption cf 156
Accidental poisoning, skin
absorption of pesticides 158
Of X-rays and gamma rays 167
Extraction of pesticides
from water using carbon
absorption method 174
Analysis of 2,4,5-T in soil
by ultraviolet absorption 203
Of yolk sac of Hsh, DDT
effect on mortality 209
Of pesticides in humans,
studies 232
Research needs, absorption of
pesticides in humans 240
Surveillance of occupationaUy
exposed persons, blood
studies to determine
hazardous absorption 242
Route of entry of pesticides 263
Percutaneous absorption,
occupational exposure 263
Route of entry of
organochlorine insecticides 264
Controlled human exposure 295
DDT, effects; differences not
associated with absorption 298
Experimental oral exposure
to dkldrin, relationship
between absorption and
accumulation 3C1
73
-------
SUBJECT INDEX
Calculations of levels of
intake, absorption, storage
of dicldrin
Modes of interactions
Organochlorines, effect of fat
diets on absorption
Benzene hexachloride toxicity,
rats, effect of high fat diet
ABNORMAL
Pesticides, effects on fish.
seeking of abnormally warm
waten
302
Health hazards of parathion,
phosdrin, TEPP, ease of
absorption 347
Systemic effects,
organophospliatcs, dependent
upon rate of absorption 360
Organophosphorus compounds,
gastrointestinal absorption'of 361
Systemic poisoning, routes of
absorption, skin,
respiratory tract 383
Study, Parathion, Paraoxon
penetration 402
Acute, chronic poisoning 407
Organophosphorus agent,
rapid skin absorption 411
Effect of fat diet on DDT
toxicity, animals, effect on
absorption of DDT < 31
Temperature effects on toxicity
of parathion. mice, rate of
absorption 432
EDTA, use in chelation of
metals, oral administration,
absorption of metal 452
Sll
Interactions of pesticide
residues with detergents,
absorption of materials
from alimentary tract 526
530
533
Human exposure to pesticides 611
Human exposures to pesticides 657
Pesticide 'cvcls and disease,
comparison of normal and
abnormal tissues, DDT, DDE 328
Organophosphatcs, occupational
exposure, EEC abnormalities 348
Diene groups, EEC abnormalities 34?
Occupational exposure, abnormal
chemistry, from Community
Studies Surveillance Programs 357
Occupational exposure, abnormal
distribution of serum and
urine amino acids 388
Occupational exposure, neurologic
abnormalities 389
Occupational exposure to DDT,
abnormalities of physical
examinations and laboratory
tests 391
Paraquat, diquat, production
of abnormal fingernail* 405
Occupational exposure,
abnormalities in behavior 407
DDT poisoning, animals,
abnormal susceptibility
to fear 425
Mutagenicity, results of
Mutz'ions, abnormalities
567
Mutations, physical
abnormalities 570
Mutations, chromosome
aberrations, abnormalities 570
571
210
Mammalian methods, of testing
for mutagenicity,
abnormalities 587
Correlation between mutation
production and chromosome
abnormalities 588
Children, abnormal at birth
recording of anomalies 600
Monitoring of gross
abnormalities . 601
Carbnyl;ebnonnal mitosis 639
74
-------
SUBJECT INDEX
2,4-D; abnormal mitosis
DCNA; abnormal meiosis
Dicamba; abnormal meiosis
Isocil; abnormal meiosis
Monuroa; abnormal meiosis
Naptalam; abnormal meiosis
Paradichlorobenzene:
abnormal mitosis
Congenital malformations,
definition
Exposure to teratogen; induction
of congenital abnormalities
Birth certificates, recording
of abnormalities
Production of abnormal fetuses;
2,4,5-T.mice
2.4D; production of abnormal
litters
Production of abnormal litters,
Dr ISO solvent
Production of abnormal
fetuses, mice
Production of abnormal fetuses
Production of abnormal fetuses
Production of abnormal fetuses
ACARIC1DES
Sulfur, polysulphides, and
related compounds
Conjunctivitis in humans
ACCIDENTS
Regulations needed to control
disposal of pesticides.
containers, sources of
accidental poisonings
Accidents from use
Needed safe methods of disposal
of pesticides, containers, to
prevent accidents
Evidence of human exposure,
ax reports, accidental
Case reports, accidental
poisoning by organochlorines,
effect*
640
640
640
641
642
643
643
657
659
662
666
666
66?
668
670
671
672
368
368
18
22
24
33
33
Manufacturer, need for label
information on procedures
in accidents
In use of pesticides
Needed methods of disposal of
pesticides, containers, to
prevent accidents
TEPP, poisoning, conditions
Potential danger to operators
Private wells contaminated
by accidental spills
2,4-D; accidental contami-
nation of well water
Potential effects of spillage
on water, transportation
Household uses, increased
danger of accidental
poisoning
Preventative mc.'juies, workers
Agricultural use of chemicals.
accidents in
Accidents, by chemical, by
industry, by occupation
In U.S., poisoning
Accidental ingestion, by
children
Accidental ingestion, by
children
Accidental incorporation of
insecticides in animal feed
Prevention of
Accidental spills
Package design, to minimize
accidents
Fumigation, effects on
non-target organisms
Seed treatment, accidental
ingestion of seeds by farm
animals, poultry
77
101
103
110
113
117
117
122
145
153
153
154
157
157
158
159
160
192
193
I9S
200
75
-------
SUBJECT INDEX
Dinoseb. accidental
contamination of lakes,
streams, effect on
aquatic organisms 203
Case reports, accidental
poisonings 231
Developing countries, accidents
from improper storage of
pesticides 234
Pesticide protection teams, to
set-up reporting system,
accidents, misuse of
pesticides 241
Effects on humans, accidental
Digestions 251
Studies of groups exposed,
occupational^, accidental 256
Home poisonings, children 263
DDT, accidental ingestjon of 296
DDT, accidental Digestion of 297
Mortality rates, accidental
poisonings 305
Accidental Digestion of
pesticides, children 306
Accidental Digestion, children 308
Epidentics of poisonings,
accidents, pesticides 310
Pesticide poisonings, accidents 314
DDT. dieldrin, comparison with
persons accidentally killed 322
DDT residues, hunrns, killed
accidentally 329
Accidental poisoning of adults 356
Gentian violet, accidental
exposure, effects 364
Occupational accidents.
pesticides 366
Bsdrin accidental occupational
exposure of human, eye 367
Dinitrophenolic pesticides,
accidental exposure to 368
CUordane. accidental
Digestion of 372
Accidental exposure, humans 383
Aviation accidents, pilots 406
. Study of DDT, DDE storage in
various population* 430
Protection of eyes from
accidental contact of
pesticides 443
Accident rate for aerial sprayers
vs commercial pilots 446
Accidental discovery that
chtordane causes enzyme
induction, animals 517
Dairy herd, accidentally
exposed to aldrin-contaminatcd
feed 529
Population monitoring.
accidental ingestion 661
ACCUMULATION
Of pesticides in the environment 22
Needed studies on rates of
accumulation of pesticides
in the environment 23
Carbarn? te insecticides, not
accumulated in fats 64
Phenylacetk add, not expected
to accumulate in soil from
year to year 68
Of pesticides in the environ-
ment ' 101
Spray appb-jtkm for spruce
budworm, not accumulate in
pbnt and animal systems 111
Shellfish, accumulators,
proposed as monitors of water
quality for pesticides 118
Pesticides in water, increased
biological accumulation in
food chain 120
76
-------
SUBJECT It JEX
Fate, influence on irrigated
agriculture 124
Arsenic, accumulation in soil 145
Of persistent pesticides in
adipose tissue, occupational
exposure vs general population 153
Studies on accumulation of
pesticides in environment 169
Need for assessment of rates
of accumulation in environment 174
Ammonium ion, accumulation in
soil 206
Oysters,'accumulation of DDT 208
210
Residue accumulation in fat,
fishes
Wild mammals, accumulation
of pesticides 213
Of pesticides in environment 245
Of DDT ditldrin in fat of
workers 383
Methoxychtor, little tendency
to accumulate in fat, normal
conditions 430
DDT, storage in fat, animals,
humans 435
.' •*.
Acetylcholine, at NMJ, in
pesticide poisoning 452
Effects over extended periods
of exposure, carcinogens 464
Interaction, effect on - • •>«
storage of pesticides
526
Residue accumulation in body _
tissue, time of exposure ' "•
to material - 538
ICUTE
Organochlorines, potential for
•cute toricity " 34
Organophosphates, acute toxicity 34
Effect of dietary protein on
•cute toxicity 36
Toxich) of DDT substitutes 48
Co. ^c; herbicides, acute
effects 67
Zectraii, acute oral toxicity,
in comparison with DDT 111
Effects of pesticides on fish 210
Human exposure, acute poisonings 231
Organochlorines, potential for
acute toxicity
233
Organophosphates, acute poisoning 234
Improper storage of pesticides,
acute poisoning 234
Influence of diet on acute
toxicity 235
DDT, acute effects of 246
Poisoning 251
Toxicity, terminology,
definition 259
Epidemiology of acute
pesticide poisonings 305
Agent factors, contribution to
acute pesticide intoxication 307
Acute oral toxicities, LD-50 312
Acute dermal toxicities, LD-50 312
Phosphate ester pesticides 312
Acute oial toxicities, LD-50 313
Acute dermal toxicities, LD-50 313
Chlorinated hydrocarbon
pesticides 313
, , Organophosphates, occupational
exposure, acute poisoning 347
Acute pesticide exposures.
Organophosphates 355
Oinical signs of acute
pesticide intoxication 358
Acute effects of chlorinated
insecticides, Organophosphates,
and carbamates on mammals 359
Chlorinated hydrocarbons, acute
eiTecti !<9
77
-------
SUBJECT INDEX
DDT poisoning, effects
359
Organic mercurial compounds,
acute human poisoning 362
Inorganic arsenical poisoning,
acute 362
Chlorinated phenols
pentachlorophenol, acute
dermatitis 364
Organophosphatcs, acute
poisoning, humans 367
Organophosplioms compounds,
production of acute toxic
myocarditis 371
Yellow phosphorus ingestion,
cirrhosis of the liver,
acute poisoning 371
Organophosphorus compounds,
effects on genito-urinary
system 373
Toxicity of pesticides
Poisoning, humans
382
383
Organophosphates, acute
toxicity, plasma cholinesterase 388
Organophosphates, effect on
alertness, acute poisoning 389
Exposure, humans 392
Needed population studies on
persons with acute toxicity
episodes 396
Techniques of observation,
LD-SO in skin vs parcnteral 402
Poisonings of humans through skin 404
Behavioral effects of pesticides 406
Poisoning, terminology 407
Behavioral effects of pesticides 408
Studies needed to measure
behavioral effects, doses
below acute toxicity 409
Orbaryl, acute doses, behavior
vs catechohmines 410
Chlorinated Hydrocarbons,
occupational exix>suies 4i 1
Echothiophate iodide, effect on
red cell cholinesterase,
compa-uon with pesticide
exposure 412
Metaisosystox, acute symptoms
of organophosphate poisoning 414
Occupational exposure, signs and
symptoms of acute poisoning 415
Pesticide poisoning, brain
anoxia, acute intoxication
416
Baygon, ac>;'. .*. effects, humans 417
Studies in children after
acute CNS poisoning 417
Organophosp *te poisoning,
behavioral fleets 418
Oganophosph. <•$, behavioral
effects, acute poisoning 419
Correlation between acute
toxicity, animals, occupational
hazards, humans 423
Toxicity of Organophosphates
vs acute toxicity of
chlorinated hydrocarbons 424
DDT, acute effects of 425
Oral toxicity of 16
antichofinesterase •
insecticides, rats 427
Oral toxicity of DDT, rate 428
Toxicity, DDT, rats, carbon-
tetractiloridc induced liver
damage 430
Diagnosis of poisonings, phenols
vs cholinesterase inhibitors 450
Poisonings by pesticides 454
Toxic effects of EPN and
malathion 512
Organophosphates, administered
to mice at 1/5 acute LD-SO,
effect on enzyme induction 518
78
-------
SUBJECT INDEX
ODT poisoning, use of
phenobaibital in 529
Low protein diets, rats, effect
on acute toxic effects of
pesticides 532
Toxicity, pipetonyl butoxide 542
Toxicity, Freons 545
Toxicity. Freons, effect of
pipeionyl butoxide on 546
Studies, chromosome effects 590
Study, mutagenic thresholds
of TEPA, METEPA 598
Toxicity of captan, effect
of protein on 664
ADI
Acceptable daily intake,
pesticides 137
Acceptable daily intake,
organochlorines 374
DDT in human milk 374
ADiPOSE
Accumulation of persistent
pesticides in, occupational
exposure vs general
population 153
Present in adipose tissue.
in comparison with other
foreign material 248
Organochlorines in general
population 255
DDT, presence in human adipose
tissue 255
Terminology, "persistence" 260
HEOD in adipose tissue, humans,
vs. daily intake 265
Concentrations in adipose tissue,
use as indices of total body
burden, exposure 273
Storage of DDT in, vs daily dose 276
Decline of HEOD in, rats, during
post exposure period
292
Dieldrin concentrations in,
hununs 301
Relationship to daily dose and
concentration in adipose
tissue 302
Surveys of pesticides in 320
DDT. DDE levels in 321
DDT residues in, sex
differences 322
DDT residues in. ethnic studies 322
DDT residues in. age differences 323
DDT residues in, place
variables 324
DDT, DDE residues in Alaskan
eskirnos 326
DDT in adipose, diseases 329
Human monitoring survey, levels
in adipose tissues 331
Adipose residues, VJS., human
monitoring data '" 332
Total DDT in, effects of age 335
DDE levels in, by age, race 337
Total DDT, dicldrin in, humans 338
Total DDT. dieldrin in. humans 339
Residues of p,p'-DDE, diddrin,
total DDT, humans 340
Residues of p,p '-DDE, diddrin,
total DDT. humans 341
DDE, fed to-rats, monkeys,
storage of in adipose tissue 427
DDT, DDR, dieldrin storage in
males, i females 429
Cachexia, effect on levels of
pesticides in . 496
DDT. diddrin, heptachlor. rats,
effect on storage 527
DDT in retarded, non-ambulant
patients 529
79
-------
SUBJECT INDEX
Levels in other tissue? in
comparison with adipose 536
DDT, exposure, storage of in 537
DDT, residues of DDT, DDE in
humans, household exposure 537
DDT. DDE residues in,
occupational exposure vs.
general population 538
Dieidiin levels in, rats 539
DDT residues in, beef steers 539
DDT residues in, dogs 539
ADRENAL
Use of DDD to control adrenal
overproduction 300
o.p'-DDD, atrophy of adrenals in
dogs 300
Effect of DDD on man,
other species 300
O.p'-DDD, effect on adrenals
tn roan
301
435
DDT, atrophy of adrenal cortex
DDT, storage in adrenal gland,
«titm«U 435
Need for more studies on
enzyme induction 510
Need for studies on enzyme
induction in various species 520
ADSORPTION
Reduction of pesticide levels
in water by adsorption on
activated carbon 123
Removal of toxaphene and BHC
from water by adsorption
on carbon 123
Removal of pesticides fron water 123
Pesticides analyzed from water
samples adsorbed by carbon 129
Factors to consider in reducing
hazard of soil contamination 143
Pesticide adsorption and
sofltype 143
Soil moisture and temperature,
effect on adsorption of
pesticides in sofl 144
Pollution hazard; reduction of 192
Skin adsorption annual intake
of DDT plus DDE 384
ADULT
Mosquito control, use of
malathion, naled .. 54
Insect development, relationship
of "juvenile hormone" to 83
DDE Mood levels, humans,
adults vs children
148
Humans, accidents, occupational
exposure 157
Poisonings, humans, etiology 158
Insect control, injection of
adults with juvenile hormones 165
Mosquito control, approaches to 196
Lake trout, DDT. DDE in 209
Insect control, developmental
phcromones 219
Volunteers, humans, information
on pesticide* 260
Poisoning cases, occupational
exposure ' 306
Population groups, pesticide
poisonings 308
Population groups involved in
poisonings 356
Exposure to pesticides 395
Behavioral effects of
pesticides 407
Acute oral toxjcity of 16
antichofinesterasr
insecticides, weanling
vs adult rats 427
Parathion, administration to
volunteers 428
Mouse, newtocm, young vs adult 484
Radiation exposure, rats,
young vs adult 533
80
-------
SUBJECT INDEX
ADULTICIDE
Persistent insecticide use
patterns 48
Mosquito control programs 48
Mosquito control 127
Adulticiding operations,
equipment used 127
ADVERSE
Develop regulations for
collection and disposal of
pesticides, containers, to
protect public 18
Effects on environmental
processes 25
DDT studies, not produce
adverse effects 34
Effects in animals, humans,
minimize exposure to 36
Reporting of effects on humans,
animals, wildlife 51
Population densities, effects of
71
Effects on biological controi,
from widespread use of broad
spectrum pesticides 82
Accidents, adverse effects 113
2,4 D; effect on mosquito
larvae, aquatic fauna 126
Effects on environmental
processes 179
Herbicides, persistence,
effect on crops 204
Wild mammals, effects of
pesticides on 213
Fertilizers, effects on spider
mites 218
DDT, exposure of human population
to, not produced adverse effects
in volunteers 233
Minimize exposure of humans,
while testing undertaken 235
Registration of new pesticides 238
Acceptable daily intake,
safety factor 249
"No effect" level 260
DDT, studies in volunteers 296
Lor.g term exposure to
pesticides 345
DDT exposure, occupational, no
adverse effects, humans 348
Chlorinated hydrocarbons 350
Biochemical parameters 351
Recommendations for prevention
of advene effects 355
Behavioral toxicity 407
Psychiatric drug literature 408
DDT. long-term exposure,
little effect 471
Genetic effects 598
Embryotoxicity, reproductive
effects equated with
tcratogenicity 663
Tes'ingfor
AERIAL
Sprtying, conditions, needs
Dispersal of particles during
aerial application
668
Chlorinated hydrocarbons, study
on reproductive effects of
DDT. humans 674
23
Research and development needs,
conditions suitable for
spraying 24
Oils, use in aerial applications 62
Spraying, conditions, needs 102
Research and development needs,
pesticides, aerial treatment 105
107
BHC, DDT. aerial vg surface
application of 108
81
-------
SUBJECT INDEX
Application of TEPP. effects of 110
Application of endrin,
concentration in pond 120
Pesticides in human populations,
aerial spray pilots 172
Farm use of pesticides, aerial
application, effectiveness 195
Application of pesticides,
commercial applicators 197
Granules, application of by
aerial or ground equipment 199
Equipment available, need for
further research 201
Licensing of commercial
operators 221
Accident rate for aerial
appliers vs commerciiJ pilots 445
AEROSOLS
Pyrethrin and allethrin
formulations 62
Aircraft*, use of to apply 105
Formulations of pesticides 108
Shelf paper, impregnated with
pesticides, hazards 146
Household aerosols, inhalation
by humans 201
Ingestion of pesticides, routes
of entry 263
Exposure to DDT, inhalation,
effects, humans 296
Chktrthkm, aerosolized, routes
of exposure, humans 445
Protection of respiratory system
from pesticide aerosols 446
Information needed on
inhalation of aerosols 511
Pyrethrum sprays, effect on
liver, rats 545
Testing, need for reflecting
routes of human exposure,
aerosols 567
Testing needed for human
exposure to aerosols 602
Household pesticides, aerosols,
need for testing 611
Product form, aerosol(A) 645
Need for testing, inhalation
of aerosols 657
AGRANULOCYTOSIS
Lindane, implicated in
henutologic disorders 372
Agranutocytoss, ucith rates
1949-1958 372
AIR
Distribution of DDT and
metabolites in 9
Residues of persistent
pesticides in 9
Pesticide Advisory Committee,
provide advice on standards and
tolerances of pesticides in air 12
Prevention of residues in vt 13
Route of application,
distribution 22
Dispersal of pesticides by 25
Exposure to, of chemicals in 32
Mercury, escape into air by
volatilization 45
Interest in air pollution,
persistence 79
Route of application.
distribution 101
Movement of pesticides in 105
Microdimatology effect 107
Pesticide formulation, particle
size, concentrations of
DDT.BHCin 108
Drift of pesticides in 109
82
-------
SUBJECT INDEX
TEPP, application of. air
conditions
110
Pesticides in. from
agricultural use 113
Transportation of pesticides in 113
Inhalation of DDT in, humans 114
Persistence of pesticides in US
Drift of pesticides in 132
Exposure of humans to pesticides,
foods vs air or water routes .38
Volatilization of, into air 143
Wind erosion, residues in,
transportation of 145
Concentrations of ttndane in
home vs. manufacturing plants 149
Compressed air for occupational
exposure, facemasks 151
DDT, hazard from indoor vs
. outdoor exposure 1SS
Concentrations of parathion
over crops 156
Air-radiation produced
sterility, insects 164
National Air Pollution Control
Administration,
responsibilities 168
Monitoring program needed to
study levels of pesticides
in air 169
Pesticides in
172
Techniques for measuring
pesticide levels in, vs.
food, water 173
Sensitivity of method, limited
by amount of air sampled 174
Movement of pesticides in 175
Diagram, movement of
pesticides in 176
Dispersal of pesticides by 179
Leakage of pesticides into 192
Application of pesticides by,
amount reaching soil 195
Adult nosquito control,
con:amination of air 197
Drift cf small particles in 201
Exposure of humans to other
chemicals in 231
Data needed for specific media 237
Absence of data on natural
carcinogens, mutagens,
tcratcgens in 262
Effluents, improved technology 308
326
Sampling techniques for
residues
Gentian violet dust in,
conjunctivitis, nosebleeds
368
Agricultural application of
pesticides 384
Annual intake DDT, DDE
estimates for 384
Parathion in, exposure to,
humans 402
Kerosene, Xylene in,
effects from 417
Accidents, agricultural
applicators vs airplane
pilots, commercial 445
Simultaneous exposure to many
chemicals, including air
pollutants 525
Needed study, piperonyl butoxide
interaction with air pollutants 541
Chemicals in, tested for
mutagenicity in mice 598
Ethylene oxide in, tested for
mutagenic effects,
chromosome effects 640
AIRCRAFT
Application of pesticides by
aircraft 105
83
-------
SUBJECT INDEX
U«e in applying pesticides 105
Aircraft, effect on pesticide
spraying 105
Effect of aircraft on
dispersal of pesticide 105
Use of, for pesticide spraying 106
Effect of aircraft on
pesticide distribution 106
Pesticide application, airplane
vs helicopter 106
Helicopter, advantages over
other aircraft 106
Drift potential 109
Mosquito control, application
of oils 127
Adutticiding operations 127
AIRPLANE
Use of, in application of
pesticides 105
Type of plane vs efficiency
of application 105
Airplane, spray pattern from
vs that from helicopter 106
Hazard fiom DDT, household
vs airplane dusting 155
Potential exposure for
workers, airplane containing
TEPPdust 156
Behavioral effects of pesticides 406
Pilots, complaints from
application of pesticides 406
ALBUMIN
Serum albumin, in occupational!/
exposed persons 351
Albuminuria, present during
• poisoning, organophosphates 373
ALERT
Concern, ilerted by reports
of robin mortalities 210
Neurological abnormalities 389
Mental alertness, occupationaHy
exposed persons vs controls 389
Mental alertness, in acute
poisoning 389
Mental alertness, occupational
exposure 414
In poisoning cases 414
Hazard to an plane pilots 445
Pesticide intoxication 445
Alertness by medical
practitioner in recognizing
cases of poisonings 661
ALFALFA
Methoxychlor, use in alfalfa
weevil control 51
Heptachtor, control of
alfalfa weevil 52
Cotton pests, preferentially
attracted to alfalfa 83
Residues in alfalfa of aldrin,
heptachlor 132
Residues in alfalfa of dieldrin 132
DDT in alfalfa, residues in
cowtmOk 139
Alfalfa, strains resistant
to insects 162
^mported parasites and predator?
to control alfalfa wcivil 162
Alfalfa, resistant to diseases 162
Control of alfalfa caterpillar 163
Control of alfalfa aphkl 168
Endothall, pre and post
emergence herbicide 648
ALGAE
Need for more studies, pesticide
residues on algal
photosynthesis 25
Need for studies, residues on
algal photosynthesis 103
Marine algal •• ho tosyn thesis,
inhibition by DDT 121
Pesticides, use in swimming
pools for algae control 146
Need for observation of effects
on algae 205
Indicator of ecological changes 205
PhytopUnlcton 207
DDT, effect on algae 207
84
-------
SUBJECT INDEX
ALKALOID
Strychnine alkaloid, use as
rodenticide 72
Alkaloids, tested for
mutagenic effects 583
Alkaloid* tested for chromosome
abemtioru 583
AL!ERGEN
Patch testing 398
Patch testing with pesticides 398
ALLERGIC
Allergic dermatitis, caused
by pesticides, TEPP 364
Allergic dermatitis in workers 365
Phenolic derivatives 365
Dermatosis, from organic
mercurials 365
Allergic dermatitis in workers
from pesticides 399
Specialists reports on
potential health effects 399
Allergic contact dermatitis,
diagnosis 399
Allergic contact Jensitizzticn,
due to 2-chk>to-N-diaDyl
acetmide 399
Allergic contact sensitization
in man 399
Interpretation of information 399
Allergic contact dermatitis,
information 399
Allergic serialization potential,
information needed 399
ALLERGY
Natal allergy, exposure to
pesticides 149
ALOPECIA
Hexachlorobenzene ingestion.
from contaminated gain 364
Permanent alopecia 3f 4
ALUM
Water treatment 122
Arum coagulation, for removal
ofpestkides 122
Water featment 123
Ahim coagulation, for
removal of pesticides (2,44)) 123
ALUMINUM
UK of aluminum foil in aphid
control 219
Light reflections, physical
methods of control • 219
AMIDASE
Studies needed to evaluate liver
afiesteiase and amidase
in nun 510
Degradation of dimethoate 514
ANALYSIS
Continuous system for analysis
of pesticides in environment
needed 23
Of proposed pesticide
characteristics, before
application to tarpt area 24
Of food, for monitoring 36
Of selected alternative methods
of pen control 57
Systems analysis of pesticides
in the environment 101
Of proposed pesticide
characteristics, before
application to target area 103
Of well water, chlordane in 117
Problems of sampling, analysis 118
Of proposed pesticide
characteristics, before
application 126
Crops, study of residues,
dafly intake 135
Continuous analysis of data,
benefits 170
Soil samples analyzed 170
Analytical methods,
interpretation of results 172
Of pesticide residues in food 173
Systems analysis of pesticides
in the environment 174
Establish priorities for
research, methods of sampling
and analysts 238
Pesticide protection teams,
collection of appropriate
samples for chemical analysis 241
85
-------
SUBJECT INDEX
Analysis of tissues for DDT,
humans 2SS
Source of error in analysis
of DDT and related materials 257
Of environmental samples 258
Pesticide poisonings,
unsuspected, until chemical
analysis performed 306
Of human milk for DDT 373
Errors in data analysis 387
Standards for food sampling and
pesticide analysis needed 395
Of accidents, aerial
applicators w airplane pilots 445
Of urine, for chemicals 448
Statistical analysis of results 481
Statistical analysis of data,
humans, interpretations 536
Of bile, metabolites of MDP
compounds 547
Genetic analysis of Neurospora
mutants 573
Chromosome aberrations, analysis 577
578
Specific-locus method
(waxy locus) in pollen
Data analysis, need for
piompt reporting and analysis 601
Statistical analysis 667
ANALYTICAL
Methods, need for further
development 24
Methods, need for further
development 102
Needed improvement in
analytical methods for
monitoring pesticides 170
Methods 172
Procedures, to detect
contamination of treated seed
grab with untreated 200
Complexities, sources of error
in analysis 257
Methods for various. chemicals 319
DDT in human milk, differences
in analytical methods 374
Methods for chlorinated
hydrocarbons, blood,
development of 448
Methods, detection of DDT
in diet 472
ANAPHYLAXIS
Need for determination of
effects, direct toxicity,
allergy or anaphylaxis 455
Aplastic anemia hazards,
consideration of 261
Aplastic anemia, lindane 352
Aplastic anemia, deaths
1949-1958 372
Discussion of results 372
Aplastic anemia from
chlordane, gamma benzene
hexachloride, parathion 388
ANESTHESIA
Barbiturates, short acting for
anesthesia 425
Control of CNS hyperactrvity 425
ANOMALY
Congenital, recording of
at birth 6UO
Ousters of. interpretation of 663
2,4,5-T in DMSO, production of
anomalies 666
2,4,5-T; incidence of
kidney anomalies 666
Cubaryl plus piperonyl
butoxide, incidence of cystic
kidneys 666
Fetal anomalies, statistical
analysts 667
86
-------
SUBJECT INDEX
Pesticides yielding anomalies,
mice 668
Increase of anomalies, mice,
compounds tested 670
Increase of anomalies, mice,
compounds tested 671
Increase of anomalies, mice,
compounds tested 672
No increase of anomalies, mice,
compounds tested 673
No increase of anomalies, mice,
compounds tested 674
ANOXEMIA
Uve of oxygen or artificial
ventflation in 450
ANOXIA
Organophosphatej, health
hazards 347
Anoxic sequelae 347
Oiganophosphorus compounds 372
Liver damage vs anoxia 372
Brain anoxia from respiratory
failure 416
Acute poisoning 416
Ingest ion of piperonyl butoxide,
production of anoxia 542
ANTS
Use of aldrin for 51
Control by commercial pest
control industry 53
Ants, use of DDT for 54
Fire-ants, use of Mirex for 54
Fire-ants, use of organochlorine
pesticides in quarantine
programs 55
Use of lead arsenate as baft for 62
Use of chlordane for 151
Control by commercial pest
control industry 195
ANTAGONIZE
Antagonistic interactions,
lack of knowledge of 81
Antagonistic interactions,
between dieldrin and DDT
in fatty tissue storage 81
Antagonistic interactions,
between pesticide residues
and drug response 82
Antagonism mechanisms, use of
dimeraprol (BAL) for dictation
and removal of arsenic and
mercury from body tissues 452
Antagonism mechanism, v • of EDTA
and pcmcQlamine in he. try
metal poisonings 452
Antagonist of poisoning, use v '
atropine for cholinesterasc
inhibftoii, such as carbaryl 452
Antagonist, competitive,
atropine and acetylcnoline 452
Antagonizing muscle paralysis
caused by cholinesterase
inhibitors, use of oximes for,
such as 2-PAM Cl, or Toxogonin 453
Antagonists, use of oximes for
organophosphonis insecticides
and miticides 454
Antagonizing by
tetraethylammonium chloride
in caitwmate poisonings 454
Antagonism in the action of
one enzyme upon two substrates 524
> itagonistic effects on
autagenesis 598
ANTIBIOTIC
For controlling plant diseases 66
Antimycin as a fish toxicant 73
For controlling plant diseases 203
Antimycin A as a pisicide ; 213
Resistance to antibiotics.
mutations 572
Antibiotics, tested for
mutagenk effects 583
Antibiotics, tested for
chromosome aberrations 583
Griseofulvin, may inhibit DNA
synthesis 609
87
-------
SUBJECT INDEX
ANTIBODY
Pesticides, potential health
effects 398
Allergic contact dermatitis 398
ANTICHOLINESTERASE
Effects of anticholinesterase
on the nervous system 3S9
Behavioral effects of
anticholincsterase compounds 408
Altered behavior due to
anticholinesterase 410
Behavioral changes, humans, from
anticholinestense
administration 411
Insecticide poisoning, human,
signs 412
OccupationaLexposure, Baygon,
anticholinestense poisoning 417
Oximes, use in treating
poisoning by anticholinesterase
compounds 453
Tetraethytammonium chloride,
not used to treat
anticholinesterise poisoning,
humans 454
Needed studies on inhibitory
action of anticholinesterase
pesticides on ahesttrases 510
Needed studies on inhibition of
plasma and liver
atiesterases 513
Needed information on effect of
all anticholinesterase pesticides
on aliesterase activity 515
Enzyme induction, effect on
toxicity of
intkholinesterases 518
' Malathion, in vitro
anticholinesterase activity 524
Insecticides, banol, parathion,
effect of low protein diet
on toxicity 532
ANTICOAGULANT
Anticoagulant rodenticides 72
Uv- in controlling rodents 72
Us? as rodenticides 181
Rodenticides 214
Toxicity to cats 214
Pesticides in use 446
Rodenticides 451
Therapy for poisoning 451
ANTICONVULSANT
Effect of anticonvulsant drugs
(phenobarbital and
diphenylhydantoin) on DDE
blood levels, humans 436
Effect of repeated administration
on body burden of chlorinated
hydrocarbon insecticides 451
Effect of phenobarbital and
diphenylhydantoin on DDE
blood levels 529
ANTIDOTE
Antidotes for organophosphorus
compounds 361
Use of atropine, oximes in
humans, animals 426
Vitamin Kl.antLote
for hemorrhagic effects 451
Phenobarbital, antidote for
»cute DDT poisoning 529
Radiation 533
Effect of x-irradiation
and organophosphate
insecticides 533
Use of atropine in poisoning 533
ANT1FOULANTS
Use in paints and coatings 197
ANT1IUNGAL
Grfeeofuhrin, antifungal
antibiotic 546
Enchancement of toxicity
with other compounds 546
ANTntALARIAL
Antimalarial spraying 356
Organochlorines 356
88
-------
SUBJECT INDEX
ANTIMICROBIAL
Antimicrobial action, related
to molecular composition 66
Classification, based on
chemistry 66
ANTIMITOTIC
Effects, bibliography on 613
2,4,5-T; slight effect 642
ANXIETY
Experimental dermal
exposure to DDT 296
Effects of organophosphoroiis
insecticides on pilots 414
APHID
Pesticides before 1945 44
Ground tobacco used in France,
in 1763 to kill aphids 44
03s, used to control aphids 62
Cotton oops, use of chlorinated
hydrocarbons to control 84
Control of spotted Mphalfa
tphid 168
Central of aphids with light,
aluminum foil 219
Endrin, control of pests 648
Parathion, control of pests 652
Phospharaidon, control of pests 653
APLASIA
Marrow apUsia. radiation
exposure -^ 255
APLASTIC
Aplastic anemia 261
Hazards 261
Lindane 3S2
Apbstic anemia 352
Lindane 372
National death rates,
aplastk anemia 372
Blood dyscrasias 388
Aplastic anemia aoodated
with chlordane, gamma
benzene hexachloride and
parathkm 388
APNEA
Use of oxygen or artiflcial
respiration 450
APPETITE
Chronic exposure, pesticides,
fish 210
Chronic arsenical poisoning,
effects hu.itans 362
APPLE
Use of insecticides on 47
Carbaryl, use on 104
Malathion residues on,
food processing 141
Synthetic juvenile hormone,
control of codling moths in
apple trees 165
DDT, for control of apple
pests, effects on beneficial
insects 207
Red mites, cfuct on apple trees 208
CapUa, occupational dermatitis
apple spraying 365
Chloro-2 phcnylphenol, sodium
orthophenyl phenate,
dermatitis, conjunctivitis
in apple sorters 368
Sodium chtorophenylphenate,
effects in apple sorters 373
Leucopenia in apple growers 389
Hazards of current pesticide
use. If ucopcnia in apple
growers 392
Occupational exposure, in
apple orchards 415
DDT exposure, humans,
spraying apple trees 445
Lindane, use fot apples 650
APRICOT
2,4,5-T; tested on. effects 642
AQUATIC
Distribution of DDT in
aquatic organisms 9
89
-------
SUBJECT INDEX
Use of in aquatic areas,
precautions
Fenac, use of in aquatic
weed control
Use of in aquatic areas,
precautions
DDT, fate in aquatic systems
2,4-D application, effects on
aquatic fauna
Dinoseb. hazardous to aquatic
organisms
Diquat, aquatic herbicide.
toxicity
Dkt of aquatic species
Toxaphene. toxicity to aquatic
buna
Mictofomal enzyme activity.
Differences between aquatic
and terrestrial animals
24
68
103
Treatment of lakes with
toxaphene, effect on
aquatic life 119
Possible buildup of pesticides
in lakes, effects on
aquatic organisms 119
120
Endrin, spraying of fields,
concentration in aquatic biota 125
126
Municipal and industrial
waste discharges, treatment
to reduce toxicity to
aquatic systems 127
Program to determine
pesticide levels in
aquatic animals " 170
Minimizing hazards to aquatic
environment 196
200
Application of pesticide
granules, exposure of
non-target organisms -
Pesticide surplus, routes of
entry into aquatic
environment 202
203
205
208
s
213
436
2,4-D; use to control aquatic
weeds 646
EmlothaU, aquatic herbicide 648
2,4,5-T; use to control
aquatic weeds 6»3
ARMYWORM
Cotton pests, chlorinated
hydrocarbons 84
Rice 85
BHC, to control armyworms 85
DDT, to control armyworms 85
BHC, control of armyworms 87
Potatoes 87
DDT, control of armyworms 87
Sugar beet 88
BHC, to control armyworms 88
Oilseeds 90
Toxaphen->. control of
armyw..rms 90
Endiin, to control pests 648
ARREST
Organophosphorous compounds,
cardiac arrest 371
Cardiac arrest after paraquat
ingestion 371
CarJac arrest, sodium
Ouoroacetate (1080) 371
ARRHYTHMIAS
Cardiac arrhythmias 360
Poisoning due to organopnosphatcs 360
ARSENICAL
Arsenical, Paris Green, use
V 1865 against potato beetle 45
Inorganic .useni^als, effects
on nervous system 362
Acute inorganic arsenical
poisoning 362
Arsenical insecticide*.
occi' national expos ire 363
EKG changes from 363
ARTHROPP" m
Marine it.'. rtebrates 208
Shrimp, crabs, zooplantton
sen jtive to chemical poisons 208
90
-------
SUBJECT INDEX
Juvenile hormone of arthropods 219
ASBESTOSIS
Mesothdioma, complication of
pulmonary atbestoib
ASPARAGUS
Monuron; for control of weed
aecdttngs in asparagus
Simazine, control of pines
and broadleaf weeds in
ASSAY
Quality control assays, needed
for pathogens in control
programs
No a: Jay of interim effects
of materials on tissues
Of importance of MDP synergists
Mutation testing. Neurospora
Reverse mutation induction
Specif c-locus method (waxy
locus) in pollen
In vivo assays, advantages
Host-mediated assay, for
detecting mutagcnic
compounds
Induction of dominant lethal
mutations in animals
Domi tant lethal assay
253
65 1
653
61
487
554
573
574
578
589
594
596
597
Mammalian tests for evaluating
potential mutagenic compounds 602
Assay system, mutagrnicity
testing 639
ASTHMA
Asthma, household pesticides 149
Asthma, pesticide exposure 352
Parathion. asthmatics,
discussion of results 352
Organophosphorus compounds,
cause or exacerbate bronchial
asthma . 369
Asthma, exposure to
houKhola insecticides
ATMOSPHERE
Survival of pesticides,
photochemical reactions
Atmospheric contamination by
pesticides
Pesticides in atmosphere as
partkulates
Presence in air, dependence
uponfactou
Persistent pesticides in Marine
environmef.t, long-term
impact on atmosphere-
Insect fungus disease*, effect
of moisture, temperature on
Presence of many compounds in
air. analysis
Environment
Fumigantj, escape into
atmosphere
Aerosols, contamination of
the atmosphere
Fhytopbnkton, production
of oxygen
Agricultural areas, population
exposure from spraying
ATROPHY
Atrophy of adrenals, o.p'-DDD
Skin atrophy, hexachlorobenzene
Atrophy of adrenal cortex. DDT
ATTRACTANTS
Chemical attractants
Pherornones, other insect
attractants
Metaldehyde, use as slug
attractant
Chemical attractants, uses
Pest control
Use of infrared light sources
370
113
113
114
114
121
163
173
186
198
201
207
538
300
364
435
60
61
73
75
164
166
91
-------
SUBJECT 'NDEX
AUTONOMIC
Autonomic dystonia, DDT worken 409
AUTOPSY
Pesticide deaths, diagnosed at 306
DDT, dieldrin, analysis of
samples, ethnic differences 322
Cases, tissue residues,
pathology 328
Pesticides in body tissues 385
HepUchtor. dieldrin in
autopsy tissues 386
Pesticide levels, pathology,
autopsy tissues 391
Studies, negative evidence,
hazards of 392
Malignancies, autopsy
material 394
Malignancy, pesticides, autopsy
material 395
Oiganochlorincs in humans,
vs controls
Dominant lethal assay
AUXINS
Synthetic auxins
Use rates
Uses
AVICIDE
Avicides, uses
Aricidcs, uses
Avicides, hazard to desirable
species of birds
AXON
Axonic agent, e.g. chlorinated
hydrocarbons
Hyperexcitability of axon
495
Pesticide monitoring program,
samples obtained by 496
597
74
74
74
Hormone (auxin) analogs 604
Presumed major mode of action 604
Not suspected to produce
genetic alterations
605
73
214
214
524
524
riACTERIA
Pesticide, definition,
exclusion of 24
Microbtal control cf insect
pests, use of 60
Bactericides, toxicrty to 65
Antibiotics, use of 66
Diseases, precautions, effects on
non-target, beneficial species 82
Breakdown of chlorinated
hydrocarbons vs
organophosphates. by bacteria 143
Insect pathogens 163
Use for control of Japanese
beetle 163
Concentration of pesticides by 169
186
Breakdown processes of
environment
Application of pesticides to
final products to prevent
attack by 197
Antibiotics, use in control
of plant diseases 203
Pathogens, use of, to control
insects 216
Control of Japanese beetle 216
Control of pest caterpillars 217
Specificity of pathogens 217
Captan, mutagenic effects in
bacteria 438
Bacterial methods, point
mutations 572
Phagc and transformation 574
Plant chromosomes vs virus,
bacteru 575
Host-mediated assay, use of
bacteria 589
Host-mediated assay 594
BACTF.RICIDE
Bactericides, discussion of 65
92
-------
SUBJECT INDEX
Development of antibiotics as
bactericides 66
Agrimytin, use as bacteritiJe 66
BACTF.RIOPHAGE
Pha^e and tiansfonnation phages S74
Baaeriophage T-4 574
Characterization of mutagenfc
agents
Lead arsenate, use in baits
for ants, cockroaches
601
BAITS
Use of, for chemical attractants,
chemosterilante 60
62
72
Inorganic rodenticides, use in
Botanical rodenticides. use of
strychnine in 72
Anticoagulant rodenticide:,
use in 72
Metoldehyde in slug, snail baits 73
Chemical attiactants, use in 75
Kepone pellets, use to control
rodents 151
Chemical attractants 164
Use of light, to attract
insects to chemical bait 168
UK of chemical bait as avicide,
effects 214
Actions to improve protection
of public health 239
Improve design and development
of household bahs 239
Warfarin bah. epidemics of
poisonings 311
Uoach baits, substitution of
equally effective, less
toxic substances 356
Thallium bait, poisoning
of child 363
Application types (B) 645
BALD
Bald cypress, planting of Uees
on shorelines 168
Bald eagle, Decrease in numbers 211
Bald eagle, decrease in numbers 437
BAN
Grade IV pesticides, ban of
nonessential uses 13
DDT, banning of UK in U.S. 50
Use in malarial control overseas 50
Persistent insecticides, if
banned, use of other compounds 51
Dieldrin. heptachlor, banned
in 1968
Grasshopper control
DDT, banning of all uses,
discussion
of or banning of
BARLEY
Losses due to insects
Parathion in, epidemics of
poisoning
Mutation induction by seed
treatment
Specific-locus method (waxy
locus) in pollen
Pesticides known to produce
mutations in
Mutagenicity testing, atrazine.
carbaryl
Mutagenicity testing. DCNA,
dicamba, endrin
91
91
472
478
Carcinogenic pesticide, ban of
Potential carcinogenic pesticide,
considerations for banning of 478
Discussion of banning pesticides 488
Mutagenk pesticides, restriction
567
86
Heptachlor, heptachlor epoxide
residues in seeds, soil 133
Aldrin. dieldrin, residues in
seeds, soil 133
Development of resistant plants 162
310
576
578
584
Pesticides producing mutations in 585
639
640
93
-------
tiutagenicity testing. Isocfl
Mutagenichy testing, tinuron,
monuton
Mutagcnictty testing. photpharaidon,
simazine
BATS
Bats, control of, use of DDT
Bats, control of, use of DDT
BEAGLE
Beagle dogs, fed carbaryl.
effects
BEANS
Red Mexican beans,
2,4-D application to
Tentative guidelines, Acrolein,
furrow, beans
Tentative guidelines, Acrolein,
soybeans
Beans, development of strains
resistant to diseases
Lindane, use on beans
BEDS
Use of flolystream to control
predatory snail in oyster beds
BEES
Toxicity to bees, substitute
chemicals
Substitute chemicals, effects
on wildlife, fish
Juvenile hormone, effect on
bees
Carbaryl, effect on bees
BEEF
DDT-type residues in beef steers
BEER
Beer cans, environmental
poDution
BEETS
Sugar beets
Total insecticide usage
Chlorinated hydrocarbons,
usage on
Sugar beets, chemicals to
control pests
SUBJECT
641
642
643
48
54
664
124
124
124
162
650
72
49
49
83
208
539
220
84
84
INDEX
Sugar beets, lotses due to
insects
Tentative guidelines, Acrolein,
sugar beets
BEETLES
Paris Green, use against
potato bee tie
Aldrin, UK to control beetles
Organochlorines, use to
control beetles
Biological control, of
Japanese bcetk
Blister beetles, hazardous
compounds in
3HC, use to control rice pests
Vegetables, DDT to control
beetles
Potatoes, DDT to control beetles
Sugar beets, BHC to control
beetles
Sugar cane, BHC/Lindane to
control beetles
Tobacco, DDT to control beetles
Bacteria, for control of
Japanese beetle
Lady bird beetles, susceptibility
to DDT
Effects of pesticides on
beneficial insects
Control of Japanese beetle
Paradtchlorobenzene, use to
control beetles
Parathion, use to control
beetles
Phosphamidon, use to control
beetles
88
124
45
51
55
82
83
85
87
87
88
89
89
163
207
207
216
651
652
653
BEHAVIOR
84 Organochlorines, effect on 33
Uses of pheromones, insect
88 attractants 61
94
-------
SUBJECT INDEX
Chemical attractants,
quantities needed for those
associated with sexual
behavior 75
Induced sexual sterility 164
Radiant energy, effects on
behavior, insects 167
Research directed toward
bchaviur of persistent
pesticides 175
insecticides, effe cts in birds 212
.Repellents, effects on behavior
of mammals 215
Organochlorines, effect on 232
Research needs, studies on
behavioral effects 240
Effects of pesticides 243
Dynamic.; of behavior of DDT,
HEOD 269
Model of behavior
of organoihiorines 272
Behavioral effects of
pesticides 406
Behavior, definition 406
Behavioral toxicity 407
Clinical behavioral toxicity 408
Behavioral changes,
occupational exposure, DDT 409
Behavioral changes, cats, aldrin 409
Behavioral changes, monkeys,
endrin 410
Behavioral changes, rats,
carbamates 410
Behavioral changes,
anticholinesterascs 411
Behavioral changes,
organophosphates 412
Behavioral changes,
organophosphates 413
Behavioral changes, DFP 413
Behavioral changes,
orgauophosphates 414
Behavioral changes
orgar.0 phosphates, chlorinated
hydrocarbons 415
Behavior il chz.igcs, Baygon 417
Behavioril changes,
phosdrin/parathion 417
Behavioral effects of solvents 417
Behavioral tests 417
Behavioral changes,
organophosphates 418
Behavioral changes,
organophosphates 419
BENIGN
Benign tumors, evaluation of 4>i6
Benign tumors, results of tests 4o7
Benign and iraU^nant tumors 462
Definition of "tumor" for study 482
Benign tumors, induction of by
chemical agents 488
BERRY
Berry boxes, Dowcide-7 on 475
BEVERAGES
Chlorinate 1 hydrocarbon
pesticides 136
Dietary intake from beverages 136
Chlorinated hydrocarbon
pesticides in diet 138
Residues, not in beverages , 138
Chlorinated organic pesticides
in diet 385
Not found in beverages 385
BILE
Effect of pesticidal syrwrgists
on bile acids 543
Determination of metabolites
in rat bile 547
BILIRUBIN
DDT, use to decrease serum
bflirubin 300
DDT, used to treat biiruuiremia. 329
95
-------
SUBJECT INDEX
Decreased plasma bilirubin. DDT
admmistntion
BIOASSAY
Bioassay of 2.4.5-T
Bioassay, number of animals
Discussion of result i
Bioassays, interpretation
of results
Bioassays, extrapolation of
animal data to humans
Evaluation of carcinogenic
hazard
Food additives and contaminants
Bioassay for carcinogenic hazard
Bioassays, review of data
by Panel
Data elements acceptable to
Panel
B1OCIDAL
Biocidal materials, release into
environment, need for reduction
of
Effects of biocides in ecosystem
Mammalian biocides, and
rodenticides
Biocidal materials, release
into environment.tieed for
reduction of
Effects of biocides in ecosystems
Mammalian biocides and
, tudentiddes
BIODEGRADAT1ON
Biodegradatjkui, removal of
contaminants from water
Bfodegradation of carbonates
Bxxlegradaiion of
organophosphates
Biodegradable compounds, use of
BIOMAGN1FICATION
Registration of pesticides
Bfomagiification, information
needed
BIOPSY
Biopsy of Mood or fat samples
329
204
465
465
466
466
466
467
467
468
A£O
468
26
29
71
ISO
183
214
192
525
525
542
238
238
Biopsy, analysis for
inethoxychlor
Pesticides in body tissues
Pesticides in fat
Biopsy, analysis for DDT,
dieldrin
BIOSPHERE
Pesticides distributed in
Needed studies to determine
pesticides in
rtsticides distributed in
Needed information on
pesticides in
Needed continuous assessment
of storage and rates of
accumulation in
influence of man on
Phytoplankton, effect on
BIOSYNTHESIS
Effects of pesticides on
biosynthetic processes,
needed studies
Biosynthesis of brain amines
BIOTA
Normal biotk community
Recycling of pesticides in
btotic systems
Spraying of pesticides.
effects on ronUrget biota
Pesticide concentration in
aquatu biota
Assessment of pesticide levels
in biota
Normal Motic community
Urban areas, damage of
pesticides
Pest control
Application by trained operators
301
385
385
430
22
23
101
16«
174
186
207
2<0
410
29
120
126
126
169
183
194
195
195
Recovery of biota, between
255 applcatton*
196
-------
SUBJLCT INDEX
Decomposition of pesticides
by soft biota
Exposures to DDT, effect*
Deaths in. from treated
cereal seed dressings
Deaths in
Lady bird beetles, effect
of DDT on
201
BIRDS
DDT, metabolities distributed in 9
25
Avicides 73
Avitrol, to control 73
Quele'ox. to control 73
Anthraquinone, to control 73
Thiram, to control 73
Thallium sulfate, to control 73
Mongoose, effect on 82
Ultrasound, proposed use to
control 83
ODD in 127
Exposure to DDT. effects 179
DDE, effects on egg shell,
reproduction 189
Pest control, effects on 194
Control of pests of shade.
ornamental trees, effects on 196
200
206
207
DDE. effects on reproduction of 210
DDT, cffecu on reproduction of 210
Pesticides, effects on 210
DDT poisoning in 211
Effects of insecticide
residues in 211
Dieldrin. DDT in diet of,
effects 212
Avicides 214
Hazards to nontarget
organisms 214
Repellents, use to control 215
Mongoose, efl cts on 216
Organochlorines in eggs of 269
Ecological signals from 305
Adverse effects of pesticides
in ptedator birds 357
Chlorinated hydrocarbons.
effects in 373
Rotenone, toxkity to 426
DDT poisoning in, effects of
starvation 431
Chkninated hydrocarbons,
effect on eggshell thickness 437
Decline in population of 437
o,p'-Dt>T, effects in
Birth defects, need for
awareness
DDT, effect on race and sex
differences
Physical abnormalities at birth
Congenital malformations
BLACKFLY
Methoxychlcr, to control
bbrkfiies
665
BIRTH
Dieldrin, effect on birth weight
fa deer 213
261
386
481
Carcinogenic potential
Administration of chemical
after birth 431
570
Birth, reporting of abnormalities
by physicians, specialists 600
Proportion of, with anomalies 600
657
Occurrence of malformations
among births 662
Birth certificates, congenital
malformations 662
BITTER
Bitter taste, carbamates and
dithiocarbamates 369
Bxygon, bitter taste in mouth.
occupational exposure,
residents 369
BLACKBIRDS
Avicides, use to control 73
Troublesome species to control 73
51
97
-------
Blackflies, biting of humans
BLADDER
Bladder carcirogenicity of
aromatic amines
Pathologic evaluation
Urinary bladder, special
techniques required for
histological examination
Pesticide concentrations in
persons with carcinoma of
Bladder cancer, increased
incidence
BLIGHT
Pesticides, use to prevent
Nigtt
Crop application
Blight-resistant crop strains
BLINDNESS
River blindness
Spread by simulium fly
Use of DDT to control
Behavioral effects of
pesticides
Night blindness, airpbne
pilots
Pesticides, effects on eye
BLISTER
Blister beetles, cantharidin from
Hazardous compounds
Blister beetles, control of
Use of DDT, on potatoes to
control
BLOOD
DDT in, related to recent
exposure
DDE in, related to long term
exposure
Testing, preventive measures
DDT, organochlorines in, limits
DDE in, children
DDT. DDE in. kittens
Undane in, humans
Composition changes in flsh,
exposure to pesticides
SUBJECT
81
465
466
466
495
498
132
132
162
91
91
91
406
406
406
83
83
88
88
33
33
35
35
1 JtO
148
148
149
210
INDEX
DDT in, related to recent
exposure
DD£ in, related to long term
exposure
Tesring, preventive measures
DDY, organochiorines in, limits
Research need*, towering of
blood cbolinestense
Withdrawal of workers, blood
levels
Chemistry differences
Samples, obtaining, analysis
for DDT
Organophosphates in
Levels of pesticides in.
indicator of exposure
Levels in
HEODin
HECO in, rats, dogs
.HEODin
HEODin
HEODin
Model, transfer between
blood, tissues
p,p'-DDE in, humans
HEOD in body fat, rats,'
vs blood
HEOD in blood, liver, rats.
post exposure
HEOD in workmen, after
exposure terminated
Experimental oral exposure to
dieldrin, concentrations in
Dieldrin hi
Estimated half-life of
dieldrin in
Pestic&e levels in
DDT, DDE in. humans
232
232
234
2?4
240
242
254
255
255
260
254
265
266
267
258
270
272
273
.,285
293
294
301
302
302
320
321
98
-------
SUBJECT IND> X
Persona) variables, effect on
DDV, DDE, not dicldrin leveb 322
Ethnic differences, effect
on Itfveb 322
Socioeconomic differences,
effect on leveb 323
DDE re.idues in, humans 327
DDE, DDT levels in, cats 327
DDT, DDE in, humans 327
Organochlorines in, need for
surveillance 329
DDT, DDE in. children 336
Measurement of chants in
protein metabolism 348
Dieldrin in, humans 349
Dieldrin in, humans, occupational
exposure vs general
population 349
Lindane, blood dyscrasias 350
Occupational exposure, effects on
white blood count 351
Effects on blood uric acid 351
Occupational exposure, DDT
blood leveb 3S6
End/in, monkeys, effect on
white blood cell count
410
DDT, effects on blood pressure 359
361
Baygon testing, red blood cell
cholinesterase leveb
Chlorinated hydrocarbons,
animal deaths, dilated blood
vesseb 370
Henutological effects of
pesticides 371
Pesticides in body tissues 385
DDT in newborni 386
Blood dyscnsiu 388
Studies needed, pesticide* in
blood, general population 395
Allergic contact dermatitis 398
Parathion. effect on blood
cholinesterase, rats 411
Organophosphate, effect on
blood cholinestcf asc 411
Organophosphates, blood
cholinesterase 414
Parathion, blood cholinesterase,
humans 428
Organochlorine* in, males vs
females 429
DDE leveb in, humans, with
administration of
anticonvubint drugs 436
Ofganophospluces, blood
cholinesteraM, pilots 446
Samples, indication of leveb 447
Urine analysis, in comparison
with blood 448
Mercury in 448
Chlorinated insecticides,
analysis in 449
Use of agents for anticoagulant
rodenticide poisoning, loss
of blood 451
Cholinesterase inhibitors,
acetycholine in blood
452
Illnesses due to pesticides.
need for blood examinations 455
Human Monitoring Survey,
analysis of 496
Aliesterasc in 514
Needed methodology for measuring
enzyme induction, appearances of
metabolites in blood 521
DDE in, humans, Jicldrin
administration 528
DDE in, humans, taking
anticunvulsants 529
99
-------
SUBJECT INDEX
Dicldrin in, studies on stress,
starvation 530
Dieldrin levels in 536
Factors determining storage 537
Dieldrin levels in 537
Dieldrin in humans, occupational
exposure vs general population 538
Monitoring mutation rates in
blood cells 601
Pcntacfubrophenol, use in
schistose minis ax
mollusckide
DDT in, humans, vs daily
dose DDT
Dieldrin in. animals, vs
dieldrin in diet
DDT to. rats, during
post-exposure
652
DDE. DDT in, human pregnant
females vs spontaneous
abortion 675
BLURRED
Blurred vision, airplane pilot 446
Blurred vision, chofinesterase
inhibitors 446
Chlorinated hydrocarbons,
effects 446
BODYFAT
DDT in, monkeys, vs DDT in diet 277
278
280
DDT in, rats, vs DDT in diet 281
DDT in, monkeys, vs continuous
exposure 282
pj> -DDT in, humans, vs intake 283
HEOD in, rats, n concentration
in blood 285
DDT in, monkeys, after exposure
terminated 286
287
p,p -DDT to, steers, after exposure
terminated 288
P4> -DDA in urine,!. jmans vs
p4>'-DDTinbodyfat 291
BOLLWORMS
Cotton, pests 84
Pink boflworm 84
Spii.y boUworm 84
Use of chlorinated
hydrocarbons to control 84
Vegetables 87
DDT, control of bollworms 87
Tobacco 89
Control of boDworms, use of POT 89
BONE
o,p '-ODD, effect on bone marrow 301
Methoxychlor. effect on bone
narrow 301
Bone marrow, in vivo assays 589
BOWEL
dass.ficd organophosphorous
ag*nt. effect on bowel 412
BRADYCARD1A
Organophosphonis compounds 371
Effects oti cardiovascular
system 371
BRAIN
Sevin (carharyl) residues in
goats after spraying 139
Diazinon poisoning, vascular
pathology of 367
Pesticides in body tissues 385
Behavioral effects 407
Studies on pesticide effects
on indicators of brain
function 408
Carbaryl, Baygon, effect on
brain chofinesterase 410
Parathion, effect on brain
chclinesterase, rats 411
Occupational poisoning, use of
phenothiazines in, brain
damage 416
Sleep deprivation, chlorpromazine.
effects on 418
DDT in, rats, starvation
431
100
-------
SUBJECT INDEX
Blood, urine, equilibration
with brain levels
447
Organcchlorine concentrations in 49S
Residues of chlorinated
hydrocarbons in 536
BRAINSTEM
Chlorinated hydrocarbons 359
Detection in bninstem 359
Chlorinated hydrocarbon
insecticides, DDT, effect
on bninstem 408
BREAL
Bread, contaminated with endrin 158
BREAKDOWN
Of insecticide uoge, world
a ops
Piperonyl butorJde, effect
on breast
83
Spray insecticides, need to be
amenable to breakdown in
forest ecosystem 11!
Of chlorinated hydrocarbons vs
organophosphates. by bacteria 143
Temperature, effect on
biological breakdown 144
Bacteria, participation in
processes 186
Arsenic poisoning, tissue
breakdown 206
Products, testing of in vivo
•>ssays S89
Fumigants, breakdown products
of, exposure of general
population 612
BREAST
Human breast milk, analysis
for DDT 374
Breast-fed children, ingestion
of DDT 374
542
BREATH
Dust of homes treated with
Baygon, effects from
breathing 369
Breath, shortness of, from
inhibitor* of cholinestersse 446
BRED
breeding, for pest resistant
oops 60
Breeding, us. d with other methods
for disease resistance crops 161
Breeding populations of birds 211
Chlorinated hydrocarbons 211
DDT, dieldrin in diet of birds
bred in captivity, effects 212
Cabbage yellows, control of 217
Breeding for quantitative
mutation S86
Animal breeding, standardization
needed 660
BROADLEAF
PI tnoxy herbicides, use for
broadleaf weed control 68
Aliphatic acid herbicides.
toxicity to 69
Dinitroaniline herbicides, use
for broadleaf weed control 70
Nitrite herbicides, use for
preemergence broadleaf weed
control 70
BRONCHIAL
Pulmonary effects of
organophosphorus compounds 361
Effects of organophorus
compoi ads on respiratory tract 369
Bronchial asth'-'a from
organophosphates 369
Nasal and bronchial irritation
caused by chlorinated phenols 3VO
BRONCHITIS
Bronchitis, associated with
greater pesticide exposure 352
Parathioo, effects on general
population and asthmatics 3S2
Bronchitis, from exposure to
inorganic arscnicals 363
101
-------
SUBJECT INDEX
r.RONCHOCONSTRICTION
From topical application of TEPP 369
IttJGS
Aldrin, use against corn
bill bugs 51
Chlorinated hydrocarbon
insecticides 84
Cotton pests; lace bugs,
stink bugs 84
Rice bugs, endrin control of 85
Tobacco pests, stink bugs 89
Use of DDT to control 89
Mealy bugs, parasites
used against 162
Cinch bugs, insect pathogens
to control 163
Bug bombs, use to control pests 263
Inhalation of sprays in homes 263
Endrin, control of plant bugs,
lygus bugs 648
EULBS
Bulbs, regulation of imports 55
Organic mercury compounds,
bulb treatment 66
Ethylmercury rhlorir.', use to
control basal rot of
narcissus bulbs 649
BULLAE
Hexachlorobenzene, bullae
' formation from exposure to,
humans 364
Bullae, from paraquat, diquat,
humans 365
BURN
Inorganic herbicides, burning
effect from 67
Organophosphorus compounds,
burning of eyelids 367
Ocular burns, paraquat/diquat
exposure 368
Occupational toxicity.
chemical bums 383
Economic poisons, chemical
bums 442
Chemical bums from
organomercurials 443
BUTTER
Dairy products, effect of
enforcement oi Dt'aney clause 14
DDT dissolved in butter,
inf.estion by human, effect
on lice 298
Effect of DDT and fat in diet,
toxicity 431
CABBAGE
Vegetables 87
DDT, control of cabbage moth 87
Caiboiyl reader* on cabbage 1^4
Carburyl, half-life on cabbaje 134
Polyhedral virus of cabbage
looper 217
Virus control of pest insects 217
Brecd-ig ot resistant cabbage 217
Control of cabbage yellows 217
Endrin, control of cabbage
iooper 648
CACTUS
Biological control P2
Control of prickly pear cactus
by moth 82
CANCER
Dclarey clause 14
Possib'e effects of pesticides,
increase incidence of 36
Possible effects of pesticides,
increase incidence of 235
Need for perspective in, 261
liver cancer in humans 262
Pesticide levels and disease 328
Organochloride pesticides in
humans with 391
DDT, DDE storage in humar, ith 430
102
-------
SUBJECT INDEX
Interaction among pesticides. Uses
chemicals, suspected factors Use rates
in cancer causation 463
69
69
"Spontaneous", in humans, animals 464
Objective in cancer prevention 464
Animal testing, production of.
consideration of for humans 467
DDT, incidence of cancer in mice 471
Tumorigenicity testing 477
Results of toxic responses to
chemicals
Legislative needs
Pathological evaluation
Liver cancer
Sesame oil, use in cancer
research
Dihydrosafrole, rats, cancer
of the esophagus 54 3
Genetic alterations, possible
effects S67
Effects of DNA alterations,
chromosome breaks 60S
Ethylcarbamate, production of 607
CARBAMATES
Pesticides, cholinesterase
inhibitors 34
Pesticides after 1945 46
Substitution for DDT 49
Restriction on persistcm
pesticides, use of 51
Baygon, use of, for diazinon
resistant pests 53
Pest resistance, development of
new compounds 59
Oarbamate insecticides
Mode of action
Synergistic action with
other chemicals
64
64
65
Persistence 70
Effects /O
Toxicity to humans 70
Toxicity to warm-blooded animals 70
Examples of 70
Matacil, use in slug and snail
control 72
Carbaryl, use in US. 104
Zcctran, use for budwonn control 111
478
480
488
497
543
Potable water supply
Standards, limits
Daily intake
Residues in foods
Residues in food
Calculated daily intake
121
122
135
135
136
136
Residues in foods, diet
House and garden use,
agricultural use, 1968
138
147
Baygon, use to control resistant
cockroaches 151
Accidents, by chemical, by
industry, by occupation 154
Mode of action in insects 206
Cholinesterase inhibitors, toxic
potential of. 233
Poisonings, humans 307
Morbidity effects of
occupational exposure 347
Exposure, occupational 348
Acute effects, on central
nervous system 359
Cholinesterase inhibitors,
effects on eyes,
mucous membranes 361
Gilorinatcd carbamates, MorcMan,
effects, occupational exposure 364
103
-------
SUBJECT INDEX
Occupational^ related skin
condition 366
Baygon, efiects 367
Baygon, effects 369
LD-50 of, with varying solvents 403
Carbaryl, Baygon, effects
in rats 410
Poisonings from 442
Economic poisons, effects on
skin, general intoxication 443
Cholinesterase inhibitors in use 446
Cholinesterase inhibitors 4S2
Use of oximes in treatment
of poisonings 453
Tetraethylammonhim chloride,
use to treat poisoning 454
Ethyl carbamate, metabolism
and carcinogenesjs 484
QPC, tumorigerucity testing.
rating 490
Ethylcarbamate, tumorigenicity
testing, rating 491
Carbamates. tumorigerucity
testing 491
Exposure to, studies on
alfesterase activity 510
Cholinesterase inhibition,
interactions 512
Inhibition of aliesterases 513
Levels in diet of nun from
agricultural use 514
Toxicity, effect of enzyme
inducing agents on 518
Residues of, degradation of 525
Synergists, effect on
toxicity of 541
Synergists with 542
Isopropylphenyl carbamate,
chromosome aberrations in
higher plants 583
Mode of action, inhibition of
oxidative phosphorylation 604
May affect DNA 607
Carbaryl, usage, major
insecticide 610
CARCINOGENS
Responses in testing for, dose
related 14
Chemicals proposed for insect
sterilization, effects 83
Diethylnitrosamine, aflatoxin 261
Weak carcinogen, discussion of 262
Effects of on target tissues 464
No safe levels in foods
determinabie 464
Animals, selection of strains 465
Production of tumors 466
Interpretation of results 467
DDT. carcinogen in mice,
possibly humans 471
Testing of chemicals, establishment
of priorities 473
In animals, vs humans 482
Pathological evaluation 488
Biological alkylating agents 490
Induction of microsomal enzyme
activity 517
MDP compounds, animals 543
3,4-Benzpyrenc 544
CARCINOGENESIS
Recommended, modification of
Debney clause 14
Justification for modification
of Delaney clause 15
104
-------
SUBJECT INDEX
Needed studies on, support for
increasing incidence of
Increasing incidence of
Research needs, studies,
procedures
Areas of special study interests
Cyclamates, concern of
Determination of in animals,
humans
Potential of DDT, other
insecticides, in mice
In experimental animals, fish
Of pesticides
Panel on, responsibilities
DDT. health benefits vs
cartinogenicity hazard
Evaluation of carcinogenic
hazards
Substances in food
Reduction of exposure to
Factors influencing
Principles, criteria for
evaluation of carcinogenic
hazards
Route of administration
Number of animals
Pathologic evaluation,
classification
Tumorigenicity, index of
potential carcinogenicity
Summary
Pesticides tested, criteria
for evaluation
Category B, results
DDT, carcinogenicity in animals
Category C, results
Triphenyltin hydroxide not
tested for carcinogenicity
16
36
235
241
243
245
261
357
395
461
462
463
464
464
464
464
464
465
465
465
466
467
468
470
471
473
•
474
Recommen&tions for priority
testi.ig
Use practices, regulation with
respect to potential hazards,
recommendations
Recommendations
Methods, to determine
Oral intubation, conversion
into less carcinogenic
metabolite
Testing with neonates
Pathologic evaluation
Carcinogenic, mutagenic
interactions
No search for carcinogenic
effects of interaction at
target level
Piperonyl butoxide, not
carcinogenic for liver.
animals
Sesame oil, use in
carcinogenesis studies
Co-carcinogenicity
Co-carcinogenicity activity of
piperonyl butoxide. MDP
synergists
Freons and piperonyl butoxide
Synergistic toxkity,
carcinogenicity
Chromosome breakage, mutations
Mutagenicity, carcinogenicity
in animals, testing
CARCINOMA
DDT residues, association with
carcinoma
Aldrin, dieldrin. carcinoma
of the stomach
Organochlorine levels in
patients with carcinoma
Hazards of pesticide use.
carcinoma
476
478
479
481
-------
SUBJECT INDEX
Concentration of pesticides in
patients with carcinoma 495
Mammary carcinoma, Freon 112,
piperonyl butoxide 545
CARDIAC
Cardiac arrhythmias, symptoms in
moderate to severe poisoning
cases, organophosphates 360
Cardiac damage in wine growers
exposure to arsenical
insecticides 362
Organophosphorus compounds,
cardiac arrest 371
Compound 1080, cardiac arrest 371
Paraquat, cardiac arrest 371
Yellow phosphorus ingestion,
cardiac enlargement 371
CARDIORESPIRATORY
Dieldrin, cardiorespiratory
functions recorded, humans 301
Organophosphate poisoning,
cardiorespiratory complaints in
patients 415
CARDIOVASCULAR
Needed studies to assess
toxic effects of pesticides 16
Cardiovascular diseases in
persons exposed to
organochlorine pesticides 349
Chlorinated hydrocarbons,
effects on cardiovascular
system, animals, humans 370
Organophosphorus compounds,
effect on cardiovascular
system 371
Cardiovascular diseases,
comparison in persons exposed
to pesticides 430
CARNIVOROUS
DDD in carnivorous fish
127
Cardiovascular system, physical
exams
444
Employees of pest control
companies, cardiovascular
disturbances 449
Solar energy, use by carnivores 186
Food chain, carnivores 188
Population decline among
carnivores
Species commonly tested,
teratogenicity studies
211
CARP
Toxaphene, use to control carp 213
CARROT
Aldrin, uptake by plants, carrots 144
Lmuron, for weed control in
carrots 650
CASTRATION
Liver enzyme activity,
decreased by castration, rats 428
CASTS
Nitrogen compounds, esophageal
casts, paraquat ingestion 373
CATS
DDT, bloo I DDE, cats in homes 148
Anticoagulants, effects on cats 214
Rodenticides, effects on cats 214
DDT, DDE, cat* in homes 327
Aldrin, effect on conditioned
reflexes in cats 409
Arinphosmethyl metabolite,
metabolism in cats 426
Malathion, EPN effects in cats 523
659
CATALYZE
Effects of exposure of pesticides
to air, sunlight 115
Ultraviolet light, catalyze
oxidation of organophosphorus
pesticides 433
Conversion of parathion to
paraoxon 433
Alteration of liver microsoma!
enzymes, which catalyze
metabolism of chemicals 516
106
-------
SUBJECT INDEX
CATARACT
2,4-dinitrophenol, cataract
production 368
CATERPILLARS
Botanical insecticides,
effective against certain
caterpillars 62
Control of alfalfa caterpillars 163
Bacillus thuringieniis, control
of caterpillars 217
CATFISH
Toxaphene, use to control catfish 213
CATTLE
Methoxychlor usage, cattle,
farm buildings 51
Methoxychlor, for fly control
on cattle SI
Rotenone, control of cattle grubs 63
Cattle, acreage in Africa,
grasshopper effects 91
Annual losses of cattle products
prior to dicldrin usage 91
Water contaminated by 2,4-D,
cattle area 117
Pesticide residues in cattle 138
Excretion of pesticides in
cow s milk 139
Toxaphene, fed to cattle,
residues 139
Sevin, sprayed on cattle,
residues 139
Spraying of cattle with
i insecticides 140
Residues in meat, milk 140
Avkidrt, pest control without
contaminating cattle feed 214
CAVITY
Host-mediated assay, injection
into intraperitoneal cavity S94
CEREALS
Cereal leaf beetle SS
Quarantined pests SS
Use of chemicals on SB
Cereal leaf beetle, pests 58
Development of resistant crops 81
Stem rusts 81
Crops, insecticide usage 84
Chlorinated hydrocarbon
L-jecticides for insect
control 85
Organophosphate insecticides.
found in 136
Bromide residues in 137
2.4-?), weed control in 646
CEREPELLUM
Chlorinated hydrocarbons,
detection in 359
Chlorinated hydrocarbon
insecticides, act in 408
CERE'jRAL
Chlorinated hydrocarbons.
detection in cerebrum 359
Methylmercury, production of
infamile cerebral palsy 675
Fish consumption by pregnant
women 675
CHEESE
Possible effect of enfoicement
of Delaney clause 14
Effect on dairy products 14
CHELATING
Treatment of poisoning by
heavy metal derivatives 452
delating agents 452
CHEMOSTERILANTS
To:.icity to mammals 60
Use for insect population
control 61
Control of pests 83
Control of species 164
In combination with light traps 166
For pest control 219
Compounds used for 519
TEPA.METATEPA 598
107
-------
SUBJECT INDEX
Prediction of mutagenicity
Not registered for use as
pesticides in U.S.
CHEST
Cholinesterinase inhibitors.
tightness in
CHICKENS
Concentrations of organochlorine
insecticides in eggs
Tri-orthocresyl phosphate.
neurotoxicity in
Studies in developing chick
embryos
Teratogenicity studies
Screening tests using chick
embryos
Teratogenicity testing
Captan, Folpet, teratogenic
in embryos
Organophosphates, teratofenic
in chick embryo
o.p'-DDT, reproductive
effect in
CH1CKWEED
Potassium cyanate, control of
CHILDREN
DDE blood levels in
Poisonings in
Poisonings in
Incorrect disposal of
containers, effects on
Storage of pesticides,
effects on
Rodenticides, effects in
Exposure to pesticides
Home poisonings in
Deaths in
Deaths in
Poisonings in
602
604
447
269
424
438
438
659
659
664
665
665
650
148
157
158
159
160
214
259
263
306
307
308
Pesticide poisonings in
DDT residues in
DDT, DDE in blood of
Carbamates, exposure of
Population groups involved
in poisonings
Arsenic poisoning in
Thallium sulfate ingestion by
Breast-fed, ingestion of
DDT-dcrived materials
DDT concentrations in
Diseases, survey by
questionnaire
Poisoning in
Parathion ingesuon by
Dental caries
Inheritance of mutant genes
Search for malformations
Thalidomide, effects in
Congenital malformations.
reporting of
CHLORACNE
2,4-D; 2,4,5-T; exposure of
workers
2,4-D; 2,43-T; exposure of
workers
CHLOROPHYLL
Chlorophyll-deficient mutations
Chlorophyll mutation frequency
Mutations in barley
Amitrol, inhibitor of
chlorophyll synthesis
Mode of action of pesticides
CHOLESTEROL
DDT, fat in diet, addition of
Trop'tal, piperonyl butoxide.
effect on level in bile
314
323
336
348
356
362
363
374
386
390
417
428
485
570
600
659
662
365
450
576
576
585
604
604
431
543
108
-------
SUBJECT INDEX
CHOLIC
Effect of pesticidal synergists
on cholic acid excretion
CHOLINESTERASE
Organophosphates, effect on
Carbamates, effect on
Carbamates, mode of action
Organophosphates, effects on
Organophosphates, effects on
Pesticides, effects on
Organophosphates, effects on
Carbamates, effects on
Research needs, significance
of blood cholinesterase
lowering
Surveillance of by pesticide
protection teams
Surveillance of
Lowering of levels
Parathion, effect on
Dieldrin, effect on
Organophosphates, effect on
Carbamates, effect on
Dieldrin, effect on
Testing, detection of toxicity
Organophosphates, effect on
Organophosphates. effect on
Organophosphates, effect on
Organophosphates, effect on
Orsanophosphates, effect on
TEPP, effect on
Carbamates, effect on
Parathion, effect on
Echothiophate iodide, effect on
543
34
34
64
1S3
206
210
233
233
240
241
242
260
296
301
347
348
349
3S6
360
361
364
367
388
406
410
411
412
Pesticide effects on
Orgar.ophosphates, effect on
Paia.hion, effect on
Levels, airplane pilots
Deteirnination of levels of
Diagnosis of poisonings
EEC recordings
Inhibitors
Poisonings by pesticides.
treatment
Tolerances for inhibiting
chemicals
Potentiators of toxicity.
effects on
Organic phosphates, effect on
Mode of action of EPN, malatbion
Parathion, effect on, effect of
low protein diet
Organophosphates, effect on
CHROMATID
Characteristics used to classify
chromosome breaks
Characteristics used to classify
chromatic! breaks
Breaks
Breaks
CHROMATOGRAPHY
Gas-liquid, analysis of
pesticides
Pesticide analysis, gas liquid
DDT analysis, gas
Sources of error in analysis
Thin layer
Pesticide analysis
Thin layer
Determination of metabolites.
safrole, and other chemicals
414
425
428
446
449
450
451
452
453
512
513
514
524
532
665
590
590
592
593
170
173
257
75?
447
447
547
547
109
-------
SUBJECT INDEX
CHROMOSOME
Mutations 570
Bacterial methods for testing 572
Neurospora 573
Phage. transformation 574
Plants, use in mutagenic
testing 575
Mutation induction by seed
treatment 576
Root tip method, aberrations 577
Somatic mutation methods 577
Aberrations in higher plants,
chemicals producing 583
Aberrations in higher pUnts,
chemicals producing 584
Crosophila, screening of 586
Break studies 586
Break studies 587
Mutations, aberrations 588
Chinese hamster, uses 589
Classification of breakage 590
Chemicals producing breakage.
mutagenic effects 591
Characteristics in breakage 592
Specific locus test 595
Dominant lethal test 596
Monitoring of 601
Mice, testing 602
Breaks. DNA alterations 605
Phenols, effects on 607
Captan, aberrations 639
Carbaryl, aberrations 639
2,4-D; aberrations 639
Dkhlorvos, breakage 640
Endothall. aberrations 640
Ethytene oxide, breakage 640
Ferbam, aberrations 641
HCN, breakage 641
KOCN. breakage 641
Ltndane, aberrations 641
Linuron, breakage 642
Maleic hydrazide, breakage 642
Pandichlurobenzene, breakage 643
2,4,5-T; aberrations 643
CHRONIC
Organophosphates, toxicity 34
Systemic herbicides, effect
on plants 67
DOD poisoning, effects on birds 127
Sinusitis, exposure to
pesticides 149
Pesticides, effects on fish 210
Toxicity, discussion of 259
Pesticides, effect: on health 345
Organophosphates, exposure,
effects 347
Occupational surveillance 357
Organochlorines, serum levels 358
Organic mercurials, poisoning 362
Arsenical poisoning 362
Thallium sulfate poisoning,
hair loss 365
Organic mercurial derivatives,
occupational exposure 368
Household exposure to pesticides,
bronchitis 370
Occupational exposure, workers 384
Organophosphates, effect on
cholinesterase 388
Pesticide exposure, diseases 394
Skin penetration, toxicity 403
Behavioral effects 406
110
-------
SUBJECT INDEX
Carbaryl, tats, brain amines 410
Oiganophosphates, exposure of
pilots 414
Behavioral effects,
Oiganophosphates 419
Toxicity 424
DDT, fed to rats, effects 434
DDT, exposure, humans 471
Enzyme induction measurements
needed 510
Enzyme induction measurements
needed 5 '.9
P-peronyl butoxide. toxicity
studies 542
Ffeons, toxicity, inhalation 545
Mutagenicity testing 602
CHUBS
Er.drin in 125
CIGARETTES
Precautions for pesticide
operators 445
CIRRHOSIS
Of liver, DDT 300
Of liver, association with DDT
residues 329
Of liver, recovery from
acute poisoning, yellow
phosphorus 371
Of liver, increased pesticide
concentrations 391
CITRUS
Chlorinated hydrocarbon
insecticides, use on fruit 84
Insect pathogens 163
Studies on flies 163
Fruits, gamma irradiation 163
Fruit, control of nematodes
use of barriers 199
Crop, damage to 216
Monuron, weed seedling control in 651
CLAMS
Endrin concentration in 125
Chlorinated hydrocarbons in 129
Monitoring of pesticides in 171
Organochlorine insecticides in 208
CLAY
Particle size, pesticide
adsorption 144
Penetration of pesticides
in soU 199
Movement of pesticides in sofl 204
CLOTHING
Protective, precaution 77
Cleaning of, dry cleaning
exposure to DDT 150
Protective, for workers 153
Exposure to pesticides 155
Orchard spraymen, protective 155
Protective, exposure to
pesticides 156
Purchase of, by consumers 221
Pesticides, effect on cost
of fiber 221
Protective 250
Controlled human exposure,
effect of protective 295
DDT-impregnated, effect of 297
Protective 308
Protective 356
DDT, applied to, effects 363
Protective 444
CNS
Research needs 241
Detection of CNS effects of
pesticides in man 241
111
-------
SUBJECT INDEX
OOCARQNOGEN
Sesame oil
Safrofe, rat hepatogen
Piperonyl butoxidc
MDP synergists
COCKROACHES
Pest control
Humans, exposure to chemicals
Commercial pest control
industry
Pest control, use of DDT for
Inorganic insecticides
Lead arseiiate, use to control
Baygon, use to control
Diazinon, for resistant
Chlordane, for
DDT dust for
German cockroach, treatment for
Disease vectors
Control of
Metabolism of phosphorothionates
COCONUT
DDT, effect of fat in diet
COFFEE
Total insecticide usage
COHO
DDT in salmon fat
Salmon, effect of wastes on
Concentration of residues in
salmon
Effects of pesticides on salmon
COLLAPSE
Organophosphate insecticides,
effect on thermo-regulation
in animals
rnirtN
543
543
544
544
53
53
53
54
62
62
65
151
151
151
151
164
263
555
431
84
13
119
220
357
533
Stain of pollen grains
Specific locus test
Endrin, light colored
CQRLESS
Acrylonitrile, liquid
Atratone, crystalline solid
Captan, to buff powder
Carbaryl. crystalline solid
Chloroform, liquid
2.4-D; powder
DDT, or cream colored
Dichlorvos, to amber
Ethylmcrcury chloride,
crystalline solid
Formaldehyde, gas
Potassium cyanate, crystalline
needles
Lindane, odorless crystals
Linuron, crystalline solid
Monuron. crystalline solid
Maleic hydrazide
Faradichloiobenzene, crystals
t hosphamidon, oil
Propham, crystals
Simazine, crystalline solid
COMA
Signs and symptoms of
pesticide intoxication
Effects on the nervous system
Miscellaneous pesticides, effects
Behavioral effects of solvents
Effects of kerosene or xylene
in air
CONGENITAL
Reporting of abnormalities
Malformations, effects of
Malformations, definition
578
595
648
645
645
645
646
646
646
647
647
649
649
650
650
650
651
651
651
653
653
653
360
362
371
417
417
600
657
657
Cancer of. possibly related
to pesticides 498
COLOR
Plants heterozygous for
flower color 577
Human exposure, abnormalities 659
Need for standardizing
procedures in handling and
categorizing malformations
660
112
-------
SUBJECT INDEX
Population monitoring 661
Induction of malformations
in animals by pesticides 661
Recording and reporting of
malformations 662
Surveillance program 662
Use of information on
birth certificates 662
the of data from foreign
countries
663
CONJUNCTIVITIS
Effects of pesticides on the eye 366
Caused by chloro-2-phenylphenol 368
Caused by sodium orthophcnyl
phenate 368
Caused by Gentian Violet dust 363
Caused by sulfur, sulfur
compounds 368
Caused by lime-sulfur mixtures 368
CONTAINERS
Needed instructions for
PCB analysis, sources of
erroi, storaf in plastic 258
Parathtan, poisonings 306
Safety, children 308
Poisonings, improper
disposal of 356
Dowcide-7, use on 475
CONTAMINANT
Phenoxy acid herbicides,
irrigation water 124
Organop:tosphates, manufacture of 153
in air, exposure of workers 153
Steps for removal of from water 192
Graded actions 240
Study of environmental
contaminants 463
disposal of
Needed regulations for
disposal of
Needed safe methods of
disposal of
Purpose of labels on
Needed methods of collection
and disposal of
Needed safe methods of
disposal of
Design of, needed to prevent
accidents
Disposal of used
Corrosion of. environmental
pollution
Disposal of
Disposal of
Accidents, improper storage
of pesticides in
Needed standards, labeling of
Disposal of
18
18
24
76
78
103
157
159
193
194
201
234
242
242
rood additives and contaminants
Use permitted if non-o>rcino«enic
In foodstuffs
Persistent pesticides
Levels of exposure to MDP
compounds
In foodstuffs
CONVULSION
Endrin, effect on dogs
DDT. effect on birds
Diene group, studies in
patients
Chlorinated hydrocarbons
Signs and symptoms of poisoning
Chlorinated hydrocarbons,
effect on animals
Miscellaneous pesticides, effects
Effects in children, poisonings
DDT poisoning, animals
Therapy, to control
467
467
472
472
560
611
158
211
349
359
360
370
371
417
425
425
113
-------
SUBJECT INDEX
Poisoning by dinitrophenol and
pentachlorophenol 450
Use of diphenylhydantoin to
control
Fats in diet, effect on DDT
toxicity
451
COOKED
Heptachlor epoxide residue in
raw and cooked meat ftom
cattle 138
Use of lime-sulfur mixtures,
cooked or uncooked, on fruits 368
CORN
Use of peiucides on 47
Aldrin, use on 51
DieldriR, use to control pests 52
Use of organophosphates on 104
Acrolein. use on 124
Dieldrin, use on 133
Resistant strains 162
Avicides, use around 214
Crop rotation 218
1
2,4-D; use for weed control on 646
Dicamba, use in 647
Endrin, use to control pests
Linuron, use for weed control in 650
Parathion. use to control
bisects
CORNBORER
Resistant plants
Imported predators and
parasites to control
CORNEAL
Paraquat, effects on epithelium 368
Nitrogen compounds, effects on 368
Effects of propellants on
CORNEUM
Enzymes in stratum corneum
CORROSION
Packing materials 159
Failure of container, from 193
Industrial cooperation 242
Design of containers to prevent 242
CORTEX
o,p '-DDD, effect on adrenal
enzymes
300
418
Seconal. effect on corturj
activating system
Chlorpromazine. effect on cortical
activating system 418
DDT, effect on adrenal 435
EEC recordings in pesticide
poisonings 451
Induction of enzymes in adrenal 50
Need for study of induction of
520
COSMETIC
Food, Drug and Cosmetic Act 14
Effects on skin 363
Delaney clause of Food
Additives Amendment 480
Food, Drug and Cosmetic Act 486
Exposure to, interactions 5?S
648
650
652
162
162
368
368
368
401
COITON
DDT, use on
DDT, use on
Endrin. use on
Insecticide usage on
Carbaryl, use on
Acrolein
Resistant varieties
2,4-D; tested on
Carbaryl, use on
DDT, use on
43
47
52
84
104
124
162
639
646
647
114
-------
Endrin, use to control pests
Ethyl'.ne oxide, use on
Linuron, -X on
Paralhion, use on
COTTONSEED
In animal feed
Monuion. control of weed
seed lings in
COUGHING
Baygon treatment of houses,
effects
Cholinejtcrase inhibitors, signs
and symptoms of poisoning
COWS
Grasshopper control, cows,
acreage
Heptachlor, residues in
DDT, fed to
Spraying of, with toxaphenc
Chlorinated hydrocarbons in milk
Bromide in peanut hay, fed to
Dieldnn, concentration in
DDT, concentrations in
Concentrations of organochlorines
in milk
DDT in cow's milk, human milk
Pesticide in milk
Treatment with activated
charcoal and phenobarbital,
dieldrin residues
Dieldnn, incidence of
stillbirths in
DDT. incidence of stillbirths in
COYOTE
Chemical control measures for
CRABS
Concentrations of DDT. DDD.
DDE in
SUBJECT INDEX
648
649
650
652
138
651
369
447
91
138
139
140
140
198
265
268
269
385
484
528
665
665
71
129
Marine invertebrates
Susceptibility i.> chemicals
Exposure of. to DDT
Dieldrin, effect on mortality
Effect of ' atinj: DDT containing
organisms
Developmental pheronx-nes
Dangers to non target organisms
CRABGRASS
Metal organic compounds, use to
control
Potassium ryanate. use to
control
CRANBERRY
Movement of parathion in bogs
CREAM
Ice cream, effect of Delaney
amendment on residues in
Difobtan, dennadtis, use of
barrier creams in
DDT, colorless or cream soli J
CRICKETS
Aldrin, for con'rol of
BHC. for control of
CRUSTACEA
Exposure to pesticides.
effects on
CUCUMBER
Grown on soil treated with
aldrin. dwldrin and
heptachlor
Residues of pesticides in
CUCURBITS •
Lindane. use for
Naptalam, use for
CUMULATION
Thallium sulfzte, properties
10 year death rate bom
pesticides
DDT, in environment
DDT, metabolites, data
208
208
209
209
109
219
219
68
650
124
14
365
647
52
86
209
132
132
650
651
73
158
245
321
115
-------
SUBJECT INDEX
Compounds, stored in fat
Effects of anticholinestense
insecticides on enzyme
activity in wildlife
Organophosphates, effects on
esterase activity in wildlife
Mammalian toxicity of MDP
compounds
CUTWORMS
Aldrin, used to control
Chlorinated hydrocarbon
insecticides, used to
control cotton pests
Cyclodienes. used to control
Rice, use of DDT to control
Toxaphenc, used to control
Cereals, BHC .o control
Cyclodienes, used to control
Vegetables, DDT to control
Tobacco, use of DDT to conf )I
Endrin, use to control
CYSTIC
2,4,5-T, cystic kidneys
Carb»ryl plus piperonyl butoxide,
I Auction of cystic kidneys
CYTOGENETICS
Mammalian methods, testing
Chromosome b. eats, indicator
for «wne mutation
Studies
Testing
Dominant lethal test
Mammalian tests
Recommended protocol, testing
of compounds
CYTOLOGICAL
Pyrethrum, effects on uc liver
DDT, pyrethrum, piperonyl
butoxid:. effect on rat liver
425
Freons, pipcionyl butoxide.
510
514
542
51
84
84
85
85
85
85
87
89
6*8
665
666
587
588
589
590
596
601
603
544
544
effect on liver
Methods
Studies, flower buds
Dominant lethal test
In rats, dominant lethal assay
Monitoring human population
DEAD
ODD, toxicity to fish.
aquatic organism*
Analysis of Western grebes
for HDD
DDT, effect on worms
Human skin, effect of enzymes
on chemicals
Examinition for fetuses
Pesticides, effect on fctus
mortality and fetus resorption
DEATH
Pesticide, use
Anticoagulant rodcntkides.
mode of
Parathion, humans
Pesticide usage
Occupational, agricultural
Radiant energy, effects
Birds, seed treatment effects
DDT. eiTects on nervous system.
insects
Pesticides, effects in fish
DDT, poisonLig in birds
Acute toxicity, discussion of
Mortality, pesticide poisorin;^
Mortalities
545
577
578
596
597
601
176
126
208
401
667
668
44
72
81
157
158
167
200
206
210
211
259
305
306
116
-------
SUBJECT INDEX
Occupational poisonings 307
White phosphorous paste 309
Epidemics of poisoning by
pesticides 310
Epidemics of poisoning by
pesticides 311
Mortality studies 345
DDT, effects from solutions of 359
Organophosphates, effects 360
Organophosphates, effects 361
Organic mercurial compounds,
effects 362
Inorganic arsenicals, effects 362
Organophosphoms compounds 369
Paraqua:, mgcstion of 370
Yellow phosphorus, ingestion of 371
Rates, general population,
pesticides, aplastic anemia 372
Pesticides, skin contact 404
From pesticides 424
DDT, effects 425
Parathion. effects 428
DDT, DDE storage in 430
Matacil, effects 454
Rates, liver cancer 497
National Death Index 498
Mutations, effects on cell 569
Chromosome aberrations, effects 588
Dominant lethal mutations,
effects 597
Adverse genetic effects 598
Teratogenicity testing 659
Statistical analysis 667
DECOMPOSITION
Fungicides, properties of 65
Disposal of wastes, risks of 128
Dithiocarbamates, during
harvesting and processing of 136
Steps in processing,
manufacturing of pesticides 192
Of pesticides by soil biota 202
2,4-D; effect of soQ
microorganisms on 203
Of herbicides in soil 204
Of chlorinated hydrocarbons 366
Lindanc, thermal effects on 369
DECONTAMINATION
Of skin, in Parathion
exposure 400
DESK
Effect of dicldrin on
reproduction 213
Mammalian repellents 215
DEFECTIVE
Packaging of pesticides 159
Packaging and transportation
of pesticides 193
Cholincstcrase inhibitors,
effect on eye 367
Effects of phosdrin and/or
parathion poisoning in humans 417
Thalidomide, effects on
children 659
DEFOLIANTS
Usage, number of chemicals 67
Usage patterns 147
DEGENERATION
Juvenile hormones 165
Experimental oral exposure
to DDD 300
Effect on adrenals in dogs 300
117
-------
SUBJECT INDEX
Neurologic degenerative
conditions 394
Safrote, effect on liver in rats 543
DEGRADE
Needed research on degradation
of pesticides 16
Needed studies on degradation
of pesticides 23
Needed studies on degradation
of pesticides 101
Survival of degradation by
photochemical reactions 113
Ail, sunlight, reactive
compounds, effect on
degradation of pesticides 1 IS
Persistent chlorinated
hydrocarbons, metabolism by
plants 133
Time factor, effect on
On foods
Soil contamination
134
141
143
Moisture, effect on degradation 144
Packaging materials, need for
resistance to degradation 1S9
Need for evaluation of
degradation of pesticides 169
Factors considered in policy
decisions 174
Cumulation in food chain 192
Release of pesticide from
granules, fate of 200
Of 2,4-D, related compounds
by soil microorganisms 203
Toxicological complexities 246
Persistence 248
Factors affecting compounds 249
Organophosphorus compounds,
effects on genito-urinary
system 373
DDE. degradation product of DDT,
exposure estimates, humans 384
DDE, degradation product of DDT 386
DDA, degradation product of DDT 388
Degradablc pesticides, hazards,
carcinogenicity vs persistent
pesticides 478
Ordimethoate 513
EPN, malathion administration 523
Piperonyl butoxide metabolites 548
Piperony! butoxide, exposure
to environmental conditions 560
DELETERIOUS
Education and training to
reduce deleterious effects
of pesticides 11
Withdrawal of organochlorines 49
Effect on world food production 49
Organochlorincs, effects on
molluscs 208
DDE, effect on mallard ducks,
reproduction 209
DDT, effects on mallard ducks,
reproduction 209
Mutations in fruit flies
571
DEMYEUNATION
Organophosphorus poisoning,
paralysis with demyelination 416
DEPRESSANT
Treatment of poisoning 451
Use of phcnobarbital and
pentobarbital 451
DEPRESSED
Cholincjterases, poisoning by
pesticides 450
DEPRESSION
Of cholincstcrase levels,
pesticide poisoning 153
o,p '-DDD, effects in humans 301
Of cholinesterase levels,
pesticide exposure 389
118
-------
SUBJECT INDEX
Aldrin, effects in monkeys 410
Organophosphorus poisoning,
effects 413
Organophosphorus insecticides,
FAX workers 414
DMSO, effects on spontaneous
motor activity, rats 417
Psychosis, organophosphonis
•gents 420
Baibituntes. use in DDT
poisoning • 42S
Chlorinated hydrocarbons, effects 447
Organophosphate poisoning,
effects on respiration S34
DERMAL
Needed schem: for denoting
dermal toxicity 17
Carbanuies, irritation 70
CDAA, toxic 70
Needed scheme for denoting
dermal toxicity 77
Parathion, potential dermal
exposure, humans 112
DDT, DDD, DDE residues in
cows milk 140
Pesticides, exposure 155
Exposure, work situations 156
Parathion exposure 156
Parathion exposure 296
DDT exposure 297
Exposure of humans 307
Parathion exposure 307
Parathion, methyl parathion
exposure 308
Acute dermal toxicity. LD-50 312
Phosphate ester pesticides 312
Acute dermal toxicity, LD-50 313
Chlorin.itcd hydrocarbon
pesticides 313
Orgarophosphates, toxicity,
route of exposure 347
Diene group, studies 349
Paratliion, paraoxon studies '02
Acute dermal LD-50 values.
correlation with occupational
poisoning 423
Dteldrin, LD-50, rats 430
Parathion exposure, humans 433
DDT exposure, humans 445
2.4-D;2,4,S-T. effects on skin 450
DERMATITIS
Persistent pesticides,
production of 135
Chlorinated hydrocarbons 363
Effect on absorption of organic
phosphorus compounds . 364
TEPV, production of 364
Parathion 364
Naled, production of 364
Dithiocarbamates, production of 364
Chlorinated earbamates,
production of 364
Pentachlorophenol. production of 364
Phenolic derivatives,
production of 365
Nitrogen compounds,
production of 365
Captan, production of 365
Difolatan, production of 365
Sulfur, production of 365
Metallic derivatives,
production of 365
Chloro-2-phcnyIphenol,
production of 368
Sodium onhophcnyl phenatc,
production of 368
Allergic contact 398
From pesticides 398
Rodannitrobenzcnc, production of 399
Captan, production of 399
Phaltan, production of 399
4-chloro-2-methyl-
phenoxyacetic acid,
production of 399
Difolatan, production of 399
119
-------
SUBJECT INDEX
Chlorinated hydrocarbons,
effects 447
Pesticides, occupational
exposure 449
DESSICANT
Usage pattern, defoliants and
dessicants 147
DETECTION
Constituents in foodstuffs 14
Of pesticides in air 114
Of DDT in water 120
Of endrin in water 120
Of 2,4-D in water 124
Of 2,4-D in water 126
Of residues, chlorinated
hydrocarbons 128
Of arsenic residues in food
samples 137
Of residues in cow's milk 139
Of residues of toxaphene,
strobane 140
Of parathion in water from soil 144
Of dieldrin in runoff water 145
Use of light traps 166
Of pesticides in sur/acc waters 171
Of treated seed, contamination of 200
Compounds interfering with
detection of p,p-DDT,
p,p'-TDE 257
Of DDT in air, water 326
Of pesticides in autopsy tissues 386
EEC recordings, use 451
Tissue storage of pesticides 536
DETERGENT
Effect on persistence of
organophosphates 82
for further work on
effect of detergents on
pesticides 511
interaction of pesticides
and detergents 526
Heed for further work on
pesticides and detergent
combinations 530
Pesticide-detergent
combinations 530
DETOXIFICATION
Carbamates, rate of 64
Fungicides, bactericides 65
Of2.44-T 204
Evaluation of results,
epidemiological studies 329
Organophosphates, metabolite
p-nitrophenol 348
EOTA, use in heavy metal
poisoning 452
Koutr of administration, possible
effect on substance 487
Organic phosphate insecticides,
effect on esterases 511
Aiiesterases, effect on
malathion 513
Role of aliesterases in, humans 514
Organophosphates, effect on
enzymes , 515
Enzyme induction, effect on 517
Effect of 3-methylcholanthrene
on Guthion toxicity 518
Storage of pesticides, effect
of chemicals on 525
MDP synergists, effects 526
Dietary effects on pesticides 532
Pesticide interactions with
synergists 540
Of 3,4-benzpyreiv 544
120
-------
SUBJECT INDEX
Mode of action of MDP compounds 554
MDP compounds, effects 555
MDP compounds, effects 559
Host-mediated assty 594
DIARRHEA
Chlorinated hydrocarbons,
effects of 359
Castro-intestinal effects
of pesticides
Inorganic arsenicals, effects
Poisoning by pesticides, signs
and symptoms
DIED
Contact herbicides, effects
on plants
Analysis of birds for DDD
DDT, DDE concentration* in
persons dying from other
diseases
Morbidity and mortality survey 390
Phosdrin and/or parathion
exposure, human
DDT, DDE in persons dying from
cancer, other diseases
POots, exposure to pesticides 445
Ni'ional death index
DISPOSAL
Obsolete products, disposal of 77
Disposal of pesticide containers 159
Disposal of animals exposed
to pesticides 159
Disposal of pesticide containers 194
Disposal of pesticides, wastes 201
Metabolism of foreign compounds
by animals
DIZZINESS
DDT. effects
426
298
Chlorinated hydrocarbons,
effects of 359
Acute DDT poisoning 359
Oiganophosphate exposure, chronic 414
Metaisosystox poisoning 414
Behavioral effects of solvents 417
Symptoms of poisoning with
economic poisonings
DOG
449
361
362
450
67
126
328
390
417
430
445
498
77
159
Pests, Brown dog tick
End in, convulsion? in
Ralenticides, poisoning in
DieMrin, concentrations of
HEOD in
Dieidrin, HEOD in
DDT.HEODin
Organochlorines in
HEOD in. vs daily intake
DDF, effects in
Testing procedures,
carcinagenicity
Aramite, tumorigenicity
testing in
Dieidrin, effect on metabolism
of 6-chloro- 1 7-acetoxy
progesterone in
EPN, malathion, effects in
AMiin, DDT. storage in
DDT, residues in
151
158
214
265
266
267
269
279
300
465
470
520
523
528
539
Piperonyl butoxide, toxitity in 542
Piperonyl butoxide, excretion in 547
Teratogenitity testing in 659
Carbaryt, teratogenic studies in 664
Organochlorines,
embryotoxicity in 664
DRIFT
Aerial spraying, conditions
23
121
-------
SUBJECT INDEX
Application methods, to reduce 60
Aerial spraying, conditions 102
Pesticides in air 10S
Microdimatology effect 107
Weather conditions for
appticttion of pesticides 108
Pesticide formulation, particle
size 108
After DDT application 109
Climatic conditions, particle
size 109
Particle size, effect on 110
Pers&snce of pesticides in air 115
Applications by airplane 132
Parathion. node of application 155
Of herbicides in air 195
Forest treatment 196
Granules, pellets, control of 199
Small particles 201
Non-target effects from
herbicides 203
Phytoplankton 207
Precautions, pesticide
operators 445
DRINK
Standards, drinking water 24
Repellants, used to protect
food and drink containers 75
Standards, drinking water 103
2,4-D contamination of water 117
Cattle, contaminated wa ter 117
Standards, drinking water 121
Guidelines, drinking u ater 122
Water quality for food products 123
Spraying, precautions 126
Contamination of water supply,
devices 146
Containers, disposal of, uss of 159
Carcinogens in water,
information needed 262
Precautions, pesticide operation 444
DROSOPHILA
Mutagcnicity testing 585
DUCK
DDT, effects on egg shells in
ducks 25
Specks for monitoring
pesticides in wildlife 171
DDT, effects on egg shells
in ducks 179
DDE, effects on reproduction
in ducks 209
DDE, effects on reproduction
in ducks 212
DUSTS
Pyrethrin, allethrin.
formulation as 62
Aircraft, use to apply 105
Spraying equipment, aircraft 106
Pesticide formulations,
particle size 108
Drift of DDT formulations 109
Particle size 110
Major pesticide formulations 112
Storm, transport of pesticides 113
Pesticides in air 115
Large scale of operations 132
Pesticide levels, correlation
with dust levels 148
Insecticides, household use, DDT 151
Sodium fluoride, pyrcthrum,
use for dusting 151
Occupational exposure to 152
122
-------
SUBJECT INDEX
Exposure to endrin, humans 1S5
TEPP, exposure to 1S6
Development of resistant crops 161
Control of Japanese beetle 163
Protection of employees against 192
Incorporation during planting 199
Transport by air 201
Surveillance of dusters 242
Inhalation of 263
Controlled human exposures 29S
DDT. inhalation of 298
Dust vs pesticide levels 327
Gent-an violet, effects 364
Inhalation of, homes treated
with Baygon 369
Dhhiocarbamate exposure,
effects 369
2-chlorophenyIphenate. sodium
orthophenylphenate. effects 370
Personal protective equipment 444
Organophosphates, protection
from 444
Application form(D) 645
DYSCRASIAS
Chlorinated hydrocarbons 350
Undane, blood dyscrasias 350
Blood dyscnsis. pesticides 388
DYSFUNCTION
Occupational exposure to
pesticides 351
Neurologic dysfunctions 351
Chlorinated hydrocarbons 372
Gastrointestinal tract 372
DDT. effect on liver 372
DDT-induced histological changes 434
Hepatic dysfunction 434
EEC recordings, cortical
dysfunction 451
Chlorinated hydrocarbon
poisoning 451
DYSPNEA
Organopho5<>hates. moderate to
severe poisoning 360
Signs and sy mptoms 360
DYSTONIA
Autonomic Jystonia 409
Behavioral cnanges in workers
exposed to DDT and related
chemicals 409
DYSTROPH1C
Dystrophic hair follicles,
human, use of Fekema ES-30-9 405
Sample skin matrix 405
Nail dystrophy 405
Hair dystrophy 405
EAGLE
Monitoring of pesticides in 171
Eagles, failure to reproduce 210
Carnivores, decline in
population 211
Bald eagle, reduction in numbers 437
EARTHWORMS
Robin mortality, feeding upon
earthworms 210
ECG
Dieldrin, effects on 349
ECOLOGY
Research needed on persistent
chemicals, effect on 9
Eradication of pests 28
Concern of pesticide residues on 80
Less persistent pesticides,
effect on 161
Insect control, parasites and
predators 162
Cultural or environmental
control 164
Integrated control techniques 167
123
-------
Eradication of pests
Food web
. Herbicides, persistence in
soil
Chlorinated hydrocarbons
Surveillance system, information
Registration and review of
pesticides
Pesticide protection teams
Manufacturer, concern for
Epidemiology of pesticides
Signals from fish, birds
Effect of pesticides on birds,
fish
Chlorinated hydrocarbons,
potential hazards, u»e of
other chemicals
ECOSYSTEM
Needed increase support for
research of pesticides on
Application of pesticides,
knowledge of
Insecticides, breakdown in
forest
Integrated control techniques
Application of pesticides,
knowledge of
' Chemicals in, movement in
Changes in, costs and value
to society
EDEMA
Organophosphorus compounds
Effects on eyes
Nitrophenols, effects
Urganophosphorus compounds
Systemic poisoning, effects
Dieldrin, effect oc cells
and liver
SUBJECT INDEX
«
182
188
205
212
237
238
241
245
305
305
357
610
16
29
111
167
183
187
220
361
361
370
369
369
EEC
Dieldrin, effects on
Dkldrin. effects on
Organophosphorus compounds.
effects
Diagnosis of poisonings
EGGS
Delaney clause, effect on
DDT, effect on egg shells, birds
Inject control, residue at
various stages of life
OQs, effect on mites, aphids
Sterility, effect on
Radiation, effect on fruit fly
DDT, effect on egg shells, birds
DDE, effect on egg production.
shell thickness
DDT in fish
Bird population decline, egg
breakage
DDE, effeu on egg shell
thickiv.-ss
Exaction of organochlorines in
Mutation, chromosome changes
transmission of
DDT, dieldrin, effects on
shell thickness
EGGPLANT
Carbaryl residues on
Residues, half-life in
EGGSHELL
Weight of, effects of
pesticides on
Thickness in birds fed
chlorinated hydrocarbon
pesticides
301
349
443
451
14
25
S3
62
164
167
179
189
209
211
212
269
569
665
134
134
211
437
432
DDT, dieldrin, effects on
eggshell
665
124
-------
SUBJECT INDEX
Reproductive effects 665
EGRET
Toxaphene. mortality in fish
eating birds 211
ELMS
Dutch elm disease, use of
mcthoxychlor in SI
• • h elm disease control 211
7 .cct of pesticides on
robin population 211
Dutch elm disease, control of 218
EMBRYO
Need for knowledge, effect
of chemicals on embryos 455
Embryo homopcnates, tests 589
Captan. human embryo, effects on 639
HCN, mammalian embryo.
effects on
640
Chick embryo, screening method 659
Testing of non-human primates 661
Captari, folpet, teratogenk in
chick embryo 664
EMBRYOLOGICALLY
Organochlorines, effect on
development of molluscs 208
Death, embryonic stage 569
Dominant lethal test 596
EMBRYOTOXIOTY
Use of lower mammalian species,
donge. effects 659
Organochlorines, dieldrin.
chtordane, kepone toricity in
rats, dogs 664
Organophosphates, effects 665
EMOTIONAL
AUrin, effects in monkeys 410
Organopbosphate exposure.
humans 414
Behavioral changes, pesticides 418
ENCEPHALITIS
Encephalitis, control of
ENCEPHALOPATHY
Thattoto.xicosu, effects
DDT, induction of, humans
Species differences to
chemicals
Activity of, sewage
differences'
196
363
ENZYMES
Organophosphates, inhibition of
cholinesterase 34
Carbamates, inhibition of
cholinesterase 34
36
Organophosphates, inhibitor of 64
Carbamates, ini libition of 64
Organophosphates, effects "-. 81
Effect of plant characteristics
on residue 134
OrganophosphatRS, parathion,
effect on 206
Organophosphates, inhibition of 233
DDT, induction of. humans 235
DDT, induction of, humans 246
DDT, effect in selected jaundiced
patients 300
DDT, induction of, humans 329
Induction 347
DDT, induction of, humans 356
DDT, induction of, humans 357
Organophosphates, inhibition
of, humans 360
Organophosphates, effects on 361
Induction 388
In stratum comeum, hydrolysis
of chemicals 401
Organophnsphates, effect on 425
426
428
125
-------
SUBJECT INDEX
DOT, methoxychtor 430
Liver. DDT effects 432
Induction 434
•;.-faction of. liver microsomal 43S
Liver microsomal, infrastructure
changes 436
DDT, chlorinated hydrocarbons,
effect on, reproduction 437
Liver, activity, newborn vs
adult mice 484
Microsomal activity, induction
01, need for study 510
Induction of SI I
Aliesterases, activity 513
Malathion toxicity 514
Activity, pesticide interactions
through alteration of 516
Induction 517
Organophosphates, effect on 518
Induction 518
Induction 519
Induction, need for information,
studies in progress 520
Induction, research needed 521
Induction, chlorinated
hydrocarbons 524
Detoxification of pesticides 526
Induction, storage interactions 527
Induction by drugs 528
Induction, effect on blood
levels 529
Induction, humans, need foi
information 530
Detoxifying, diet, effect on
toxicity 532
Activity, effect of
Organophosphates,
irritants, cold stress
Physical factors, effect on
fiperonyl butoxide, MDP
compounds, effect on
Effect of 3,4-benzpyrene,
piperonyl butoxide en
533
534
540
544
548
Fate of MDP compounds
Mode of action of MDP compounds 554
Mode of action of MDP compounds 560
Compounds which may affect DNA 606
Induction, testing 660
EPIDEMICS
Organophosphate insecticides 34
Spillage of concentrated
chemical into bulk food,
water sources 34
UDT, halting of typhus epidemic 46
Bacillus thuringiensis, use
against caterpillars 217
Organophosphate pesticides 234
Spillage into bulk food,
water suppl- 234
Or pesticide poisoning 307
Legislation to handle pesticides,
foods, separate in
transportation 308
Of poisoning by pesticides 310
Accidents, human environment 383
Due to Naled, occupational
exposure 399
EPIDIDYMAL
Dominant lethal test, mice 597
Duration of spermatogenesis,
mice 597
EHLEPTIFORM
Diene group pesticides 349
126
-------
SUBJECT INDEX
Occupational exposure, human.
effects, convulsions
DDT poisoning, animals
EQUirMENT
• Meal organic fungicides, uses
Costs of introduction of new
pesticides
Spr tying
Selection of spray
Spray, drift
Mosquito control
Spraying, drift
Occupational exposure, reduction
of
Transportation
Analysis of residues in food
Cleaning of
Act-on to improve protection of
public health
Improvement of
PCB s, uses
Sprav. parathion exposure
349
425
66
78
106
107
110
127
132
153
157
173
201
239
239
257
402
Programs to control pests
197
Personal protecUon against
exposure
ERECTION
Organophosphates, skin
contamination
Hair erection
Organophosphates, hair erection
ERADICATE
DDT, pesticides after 1945
DDT, malaria programs
DDT, malaria programs
Screw worm fly, programs
Flies, programs
349
425
66
78
106
107
110
127
132
153
157
173
201
239
239
257
402
444
360
360
364
46
49
50
S2
164
EROSION
Metal salts removal of in soil
Factors affecting soil
persistence, wind erosion
Parathion, analysis in water, mud
Wind erosion, hazard to public
Termite control, possible
hazards
Needed information on pesticides
in air
Surface erosion, possible hazard
to aquatic environment
Dispersal of pesticide
ERYTHEMA
Morestan. production of
crythematous dermatitis
Chlorinated phenols
Dermatitis i'rom mixture of
paint cleaner and
pentachlorophenoi
Nitrogen compound?
Contact dermatitis, erythema
ERYTHROCYTE
Experimental oral exposure
to dieldrin
Effect on erythrocyte and
plasma chotinesterase
Experimental carbamate pesticide
Cholinesterase inhibition.
brain and erythrocytcs
Benzene hexachloride, effect of
fat diet on erythrocyte
cholincs Tase inhibiting
ability of parathion
ESTUARINE
Pesticides in
Waters
Waters, pesticides in
Chlorinated hydrocarbon
pesticides in
Pesticides in
45
143
144
145
195
195
196
202
364
364
364
365
365
301
301
410
410
532
118
120
121
129
171
127
-------
St'EIECT INDEX
Pesticides in
Recreational areas
ETHNIC
Studies on pesticide* in blood,
humans
Ethnic differences, pesticide
levels
EUTROPHICATION
Lakes, eutrophkation of
Lakes, eutrophic
EXCRETION
Carbamate'. not in milk
Of pesticides in cow's milk
Of organochlorines in milk.
DDT ingestion, DDA metabolite
DDT ingestion, DDA metabolite
Panthion, urinr
Panthion exposure,
patanitrophenol in usine
Panthion, p-nitrophenol,
humans
DDT. rats
Panthion exposure. p-.iitrophenol,
humans
Chlorinated hydrocarbons, DDT,
m milk
Panthion exposure, p-nitrophcnol
in urine
Temperature, effect on
Storage of pesticides
Of MDP compounds
Piperonyl butoxide,
3-4 benzpyrene
Of MDP compounds
Of MDP compounds
208
220
148
322
118
119
64
139
269
298
299
370
373
430
431
433
437
448
533
S36
543
544
547
549
EXPLOSION
Population explosion,
reduction of
Population explosion
Beneficial insects,
population explosion
Organophosphatcs
Gastrointestinal effects,
diarrhea
EYES
DDT, respiratory exposure,
effects
Organophosphates, effects
Chemical compounds,
uviution of
Pesticides, effects on
Organophosphates, effects on
Diazii on poisoning, effects
Bidrin, effects
Caibamates, effects
Chlorinated aliphatics, effects
Paraquat, effects
Occupational exposure, effects
TEPP, effects
Metaisosystox
Organophosphates, effects
Economic poisons, effects
Preemploymcnt examinations
Mercurials, effects in mice
FACE
Occupational exposure, reduction
of hazards, facemasks
DDT, effect on sensitivity of
Acute DDT poisoning.
paresthesiasof face
Organophosphates, face mask
Protective equipment
Personal protection against
exposure
25
179
207
361
361
296
361
365
366
367
367
367
367
367
368
383
406
414
415
442
443
664
153
298
359
128
-------
SUBJECT INDEX
FALCON
DDT, egg shell thinning in
DDT. egg shell thinning in
Faiiure to reproduce young
Observations on
Exposure to mixture of DDT.
dieldrin
Decline in population
Implication of chlorinated
hydrocarbon pesticides
FASCICULATION
Organophosphosphorus compounds 369
Early phase of poisoning,
muscle fatcicuUtion
FATS
DDT in salmon
Carbamates, not cumulated in
Pesticides in seeds
Pesticide residues, diet
Heptachlor epoxide in cows
Chlorinated hydrocarbons in
Chlorinated hydrocarbons in
Pesticides in fish
DDT in mammals
Organophosphates in
General population studies
DDT in. rats
DDT in, monkey*
Dieldrin hi, dogs
Dieldrin in
DDT in
DDT in. animals
DDT. DDA in
25
179
210
211
212
437
437
369
369
13
64
133
136
139
155
156
210
213
234
255
264
265
266
267
268
272
299
DDT in
Methoxychlvr in
Dieldrin in
DOT, DDE i i. personal
variables
DDT in, socioeconomic
differences
DDT, place variables
Residues in
DDE, DDT, hcxachlorocyclohexanc
residues, humans
DDT in, humans
DDE in
DDT in
Paraquat poisoning, effect on
liver
DDT, dieldrin ir humans.
occupational exposure
Pesticides in, invironmental
exposure
DDT in
DDT in
DDT in
DDT, storage in
DDT in, rats
DDT storage, effect of sex ?
Pesticides in
Methoxychlor in
DDT in
DDT, storage in. animals
Chlorinated hydrocarbons,
storage, humans
Gamma BHC. rats
300
301
302
322
323
324
326
328
348
349
371
373
383
384
387
388
402
425
427
428
429
430
431
435
447
530
129
-------
SUBJECT INDEX
Dfeldrin, DDT, effect of
fats in diet
532
MDP compounds, mode of action 555
FATAL
Accidents, pesticide poisonings,
children 157
Ingestion of poisons 251
Pesticide poisonings, humans 305
Pesticide poisonings, humans 306
Host, pesticide poisonings
humans 308
Statistics on, needed
information 309
Clinical case reports 358
Temik, effects, human 362
Paraquat, effects, humans 370
Paraquat poisoning, humans 373
Occupational exposure 474
Occupational exposure,
airplane pilots 445
Cholinesterase inhibitors,
effects 450
FATIGUE
Experimental dermal
exposure to DDT 296
DDT. effects 298
2,4-D, occupational exposure 350
Anticholinesterase
administration, effects 411
Pilot, occupational exposure 445
Cholinesterase inhibitors 446
Symptoms of early effects 446
Poisoning sy -ptoms, duiitrophenol,
penuchlorophenol 450
DDT, effect on dietdrir excrrtion 527
Piperonyl butoxiJe, excretion
in dogs 547
FETAL
Deaths, dominant lethal test 59?
Deaths 598
Mortality, methodologies for
teratogenkity testing 658
Laboratory techniques,
needed to measure body burden 663
Malformation, phenylmercurk
acetate 664
Mortality 667
Mortality, trypan b'.ue in DMSO 669
Blood levels. DD^, DDK 675
FETUSES
Examination for fetal
malformations
2.4,5-T; Affects in rats
660
666
FECES
Excretion of Parathkm,
metabolite in
403
Methods, tentogenicity testing 667
FIBROSIS
Paraquat exposure, pulmonary
fibiosu 370
Safrole. effects in liver, rats 543
FIFRA
Registration of pesticides 7
Regulations of 7
Need to amend 8
FINFISH
Pesticides, industry concern 120
Organochlorine- 120
HNGER
Organic mercurial compounds 362
Paresthesias of fingers ?62
Chlorpronuzine. effect on
finger pulse amplitude 418
Sleep deprivation, effect on 418
FINGERNAIL
Paraquat, diquat, effect on 365
130
-------
SUBJECT INDEX
Paraquat, diquat, effect on 405
FIRE
Miiex, control of fire-ant 54
Organochlorines, use for
fire-ant control 55
Polychlorinated biphenyls,
use in fire retardants 257
FISH
DDT, metabolites in 9
DDT in salmon 13
Dclaney clause, effects 14
Toxaphene, effect on 18
Persistent pesticides, effects on 49
Substituted ureas, effect on 69
MoDuscicides, nontoxk to 72
Piscicides, effects 73
Pesticides in 120
Endrinin 125
2,4-Din 126
Chlorinated hydrocarbons in 136
Pesticides in 171
Diquat, effects on 205
Lake trout, DDT effects 209
Kills 210
Effects of pesticides in 210
Piscicides. effects 213
Hazards to, organophosphates 234
PCBiin 257
Pesticides, effects on, DDT in 357
Pesticides in diet 385
Carcinogenesis in 395
Organochloiines, toxirity to 426
Toxicity to, DDT, effect of
nutrition 431
Enzymes in 436
Dirt, humans, residues in 537
Methylmercury in, consumption
by pregnant women 675
FLEAS
Aldrin, use to control
flea beetles 51
Commercial insect controllers 53
Guinea pigs, infestation of 83
Rice, DDT, control of fleas 85
Potatoes, DDT, control of
flea beetles 87
Vegetables, DDT, control of
flea beetles 87
Tobacco, DDT, control of
flea beetles ?9
Pests, controlled by commercial
pest control operators 150
FLOUR
Contamination of grain, flour 157
Endrin, contamination of flour 158
Epidemics of poisoning 310
BHC contamination of wheat,
flour 450
FLUKE
POP, molluscicide to control
snail carriers of larval
human blood flukes 652
FOOD
Chain, pesticides in 8
DDT, use in production of 9
Residues in 10
Residues in 11
Standards needed, to reduce
residues in 12
131
-------
SUBJECT INDEX
Containing chemicals,
carcinogenicity, Delaney
clause
Cooperative efforts needed to
develop pesticides for
production of
Lindane, use of near
Production programs, use of
pesticides in
DDT, use in production of
DDT, effect on production
Pest control
Factors influencing changing
use patterns
Repellents, uses
Toxicity testing, values, costs
Pesticides in
Accumulation in chains
Estuarine areas, production of
Water quality required for
products
Chain. DDD in
Pesticides from soil to plants
Transfer of pesticides from
soil to crops
Residues in
Survey of products
Bromide residues in
Of animal origin, source of
chlorinated hydrocarbon
residues
Exposure to pesticides
Pyrethrins, use
Contamination with pesticides
Contamination, accidents
14
19
23
46
48
49
S3
58
75
78
114
119
121
123
127
132
133
134
135
137
138
141
151
157
158
Containers, reuse of
Insect pathogens, ingestion of
Pesticides in
Chain, fish, wildlife in
Exposures, population
Measurements of pesticides in
Nontaiget organisms, use as
Chain, DDT in
Web, DDT in
Chain, accumulation of
materials in
Fish, pesticides in
Insecticides in
Loss of, residues in
Pesticides in, accidents
Contamination, control of
Residues
Epidemiological complexities
Carcinogens, teratogens,
mutagens in
Residues on, ingestion of
DDT in, ingestion of, human
Dieldrin ingestion
Epidemics of poisoning by
pesticides
DDT intake, dietary
Monitoring of residues
Pesticide spilled in.
accidental
Agricultural application of
pesticides
Pesticides in
DDT in, consumed by humans
159
163
170
171
172
173
180
187
188
192
210
212
220
234
239
2*0
250
262
263
298
301
310
326
357
383
384
385
394
132
-------
SUBJECT INDEX
Pesticides in, needed studies
395
Contaminated with parathion,
ingestion. human 428
DDT in, rats, effects 434
Presence of carcinogenic
substance in 464
Additives, route of
administration 465
Additives, use, conditions 467
Chemicals registered for use
on food crops
Residues on
Effects of interaction on
pesticide storage
Additives, mutagenic effect*.
chromosome aberrations
469
470
Chemicals registered for use
on food crops
Chemicals registered but not
for use on food crops 470
Chemicals registered for use
on food crops 473
Chemicals registered but not
for use on food crops 473
Chemicals registered for use on
food crops 474
Chemicals registered but not
for use on food crops 474
Chemicals registered for use on
food crops 475
Chemicals registered but not
for use on food crops 475
Residue, potential carcinogen 478
Needed information on human
intake, synergists 511
512
Enzyme induction, needed studies
on levels in food 519
525
Residues in, ingcstion. humans 537
Plperonyl butoxide, tolerances 543
Freons, use as propellants 545
Additives, testing for
irutagenicity in mice
Ethylene oxide, fumigant
Organophosphates
598
Recommended program for
nutagenesis testing,
pesticides used on crops 602
649
Pesticide residues in,
organomercury compounds 664
FORAGE
Methoxychlor, use on
forage crops 51
Excretion of pesticides in
cows milk 139
Resu'.ues, forage crops fed
to cows 139
Arsenic, effect on forage crops 145
Carbziyi. control of insects
or. forage crops
646
200
FOXES
S;ath from pesticides
Cereal seed dressings
containing aldrin, dieldrin,
heptachlor 200
FUMIGANTS
Entrance into respiratory system 62
Effects on insects 62
64
583
Methyl bromide, hydrogen
cyanide, para-dichlorobenzene,
uses 65
Nematocides, action 70
Hafogenated hydrocarbon
nematocides 71
Volatile liquids, gases 198
Soa 205
Soil 206
VS. pesticide production,
annual 315
Chlorinated aliphatics 367
Methyl bromide 611
-------
SUBJECT INDEX
Application form
Aciylonitrile, use
Chloroform, use
Ethylene oxide, use
Paradichlorobenzenc, use
FUNGICIDES
Pesticides after 1945
Production, usage
And bacteritides
Inorganic
Antibiotics
Organic mercury compounds
Metal organic
Di'hiocarbamite
Chlorine containing
Miscellaneous
Usage patterns
Accidents, by industry,
by occupation
Seed furrow treatment
Heavy metals in
US. pesticide production,
annual
Organic mercury compounds,
poisoning
Cap tan, occupational dermatitis
Difolatan, occupational
dermatitis
Occupationally related skin
conditions
Sulfur, polysulfides and
related compounds
Used for seed treatment,
poisoning
Difolatan, occupational
dermatitis
Captan, folpet, difolatan
teratogenic activity
645
645
646
649
651
46
47
65
66
66
66
66
66
67
67
147
155
199
202
315
362
365
365
366
368
383
399
438
Poisonings, occupational
exposure
Effects
Organic mercurial, mercury in
body fluids, diagnosis and
treatment of poisoning
Fcrbam, use of deferoxamine
in treatment of poisoning
Tested for tumorigenicity
Structure-activity-relations
Use in agriculture
Application form(F)
Captan, use
DCNA.use
FUNGISTATIC
Phenolic derivatives,
dermatitis
GARDENER
Educational efforts needed
Accidents, by occupation,
by industry
Educational efforts needed
Classes of applicators.
amateur gardeners
Inhalation of pesticides by
GARLIC
Herbicide for, economics of
Limited markets .
GASTRIC
Paraquat, ulcers
Gastric lavage, for poisoning
Intubation of mice
Papillomas, incidence of
GASTROINTESTINAL
Occupational exposure,
pesticides, effects
Organophospnates, effects
442
443
448
452
490
604
610
645
645
647
365
27
154
181
194
480
80
80
373
450
484
486
351
361
134
-------
SUBJECT INDEX
Ttallhirn sulfate, effects 363
Yellow phosphorus ingestion,
effects 371
Chlorinated hydrocarbons, effects 372
Crganophosphate, effects 411
Ciganophosphates, occupational
poisoning, effects 415
Fteemptoyment examinations 443
Occupational exposure, effects 449
Needed research, enzyme
induction S10
Needed research, enzyme
induction 520
Fat in diet, effect on storage
of gamma BHC 526
GAVAGE
Administration of compounds 667
GENETIC
Giberellins, uses 74
Manipulation of pest
populations 219
Need for perspective 261
Kutagenicity of pesticides 567
Importance of mutagenicity as a
public health hazard 568
Mutations 569
Defects 570
Mutations 571
Nettrospora, studies of
attentions 573
Pnage and transformation 574
Mutation induction by seed
treatment 576
DraophOa testing in SSS
Cytogenetics and somatic cell 587
Testing, systems 589
Classification of chromosome
breakage 590
Host-mediated assay 594
Dominant lethal test 596
Adverse effects 598
GENITOURINARY
Diazinon poisoning, pathology 367
GESTATIOK
Teratogcn icity. related to 658
Tentogcnicity. period of 659
Timing of cycles 661
Administration of chemicals
during 661
Carbaryl. beagle dogs,
teratogcnic effect 664
Mercurials 664
Pheny! mercuric acetate,
fetal abnormalities in mice 664
2,4,5-T; rets, abnormalities 666
Methods of study, mice 667
GIDDINESS
Organophosphates, chronic
exposure 414
Humans, effects 414
GLAUCOMA
Echothiophate iodide, use in 412
GLIOMA
AWrin.dicldrin,
occupational exposure 351
GLOMERULONEPHRITIS
Aldrin, dieldrin, occupational
exposure 351
GLOVES
Protective equipment 77
Exposure, conditons 148
Personal protective equipment 444
Protective eoutpment 444
135
-------
SUBJECT IHDEX
GLUCOCORTICOSTEROID
Organic phosphate insecticides,
chemical irritants, and cold
stress, increase plasma
level of
GLYCOSURIA
Occurrence during late acute
and early convalescent
stages of poisoning,
organophosphates
GNAT
Use of ODD against in
lake water
GOATS
Spraying of, with Sevin
Sevin in tissue residues of
Sevin in brain fat of
Refractoriness to DDT
Piperonyl butoxide toxicity to
GOGGLES
Infonnation on product
package labels
Personal protective equipment
Use while applying pesticides
GONAD
Residue levels of chlorinated
hydrocarbon insecticides in
GONADECTOMY
Effect on storage of DDT, DDE
in the rat
GOOSEBERRIES
Residue reduction of malathion
during food processing of
GOPHER
Strychnine (alkaloid and sulfate)
used in poison baits for
GRAIN
Methoxychlor, uses
Nitrite herbicides, use*
Avicide*,uae
Chtorinzted hydrocarbons
Organophosphates in
533
373
126
139
139
139
426
542
77
444
444
536
Inorganic bromides in
Contamination of
Resistant plants
Contamination of grain
Avicides, hazards
Epidemics of poisoning
by pesticides
Hexashlorobcnzene contamination
of, human ingestion
137
157
162
200
214
311
Hexachlorobenzene contamination
of, human ingestion 364
372
Piperonyl butoxide. tolerances on 543
Pollen 578
Acrylonitrile, fumigant for 645
Chloroform, fumigant for 646
Dicamba, use for weeds in 647
Hydrogen cyanide, fumigant for 649
Linuron, use for weeds in 650
GRASS
Use of benzoic add herbicides
against 68
Use of aliphatic acid herbicides
428
141
72
51
70
73
135
136
against
Useofdinitroaniline
herbicides against
Use of organic phosphate nematitide
against soil insects and
nematodes in
Grasshoppers n. cattle in
Argentina
Bacteria spores used against
Japanese beet.es feeding on
Use of Dicamba on
Use of MH (maleic hydrczide) on
Use of Propham on
Useof Simazineon
69
70
71
91
163
647
651
653
653
136
-------
SUBJECT INDEX
GRASSHOPPERS
Pests
Rice pests
Aldrin, use in control of
58
85
85
Control of, by chemicals 91
Insect pathogens, to control 163
Endrin. use to control 648
GRAPES
Monuron, control of weed
seed lings in
651
GREKNHOUSE
Occupational^ exposed workers 172
DFP, behavioral changes in
workers 413
Precautions for applying
pesticides in 444
Plants grown in, mutagcnicity
testing 576
GROUNDNUT
Oil seeds, use of chlorinated
hydrocarbons 90
GROUNDWATER
Pesticides in 144
Leaching from soil 144
Study of pesticide levels in 169
GROVES
Barriers to prevent pesticide
movement 199
Workers it tangerine groves 365
Difolatan dermatitis 365
GRUBS
Aldrin, use to control 51
Rotenone. use to control
cattle grubs ' 63
Cotton crops 84
Chlorinated hydrocarbon
insecticides 84
Cydodtenes, use to control 84
Cereal oops 85
BHC, use to control 85
Bacteria, use to control 163
GUERNSEY
DDT. residue in cow s mill 139
GUINEA
Pigs, use to collect fleas 83
Pig, use for allergy studies 399
Rotenone, toxicity to
guinea pig 426
Pig, metabolism of azinphosmethyl 426
Ethyl fenthion, toxicity to
guinea pig 429
Malcic hydrazide, tested in
guinea pig, effects 642
GULLS
Avicides, use to control 73
Avitrol. use to control 73
Toxaphene, mortalities in 211
GYPSY
Moth, lead arsenate used to
control 45
Moth, enforcement of quarantine 55
Moth, insert pest 58
Moth, DDT use to control 60
Moth, Sevin use to control 60
Moth, imported parasites to
control 162
Moth, DDT use to control 209
HAIR
Organophosphates, topical
effects ; 360
Organophosplutes, effects 36*
Chlorinated acW derivatives,
2,4-D;2,44-T; effect on
growth of 365
Thallium sulfate, loss of 365
Sample skin matrix 405
Hair dystrophy 405
Pesticides, effects on keratin
producing structures 405
Chromosome aberrations, studies
in stamen hair 577
137
-------
SUBJECT INDEX
Stamen hairs, studies 578
HALF-LIFE
Of heptachlor epoxide, vs
parent impound 133
Of carbaiyl on cabbage and
eggplant 134
Of Guthion on lemons and oranges 142
Of dieldrin in blood of man 302
Of captan in serum 603
Determination of, need for in
test animals 660
HANDS
Exposure to pesticides 112
Exposure to pesticides 148
Organic mercurial compounds,
tremors of 362
Paraquat, diquat exposure 36S
Chlorinated acid derivaties,
2.4-D;2.4,5-T;
hyperpigmentation of 365
Persona] protective equipment 444
Mercury poisoning, tremors of 448
HAPLOID
Neurospora crassa as 573
Pollen tubes used for chromosome
analysis S78
Pollen grain in somatic
mutation and chemical
mutagen studies 578
HARES
Killed by cereal seed dressings
containing aldrin, dieldrin,
heptachlor in England 200
HARVEST
Residues of orgapochtorincs 63
Metal organic fungicide*.
treatment of harvesting
equipment 66
TEPP, Phosdrin, Mevinphos,
we on fruits, vegetable* 133
Time factor
134
Dithiocarbamates, decomposition
during 137
Fate of malathion residues 141
Prperonyl butoxide, tolerances 543
EndothaU, use 648
HATCH
Hatcnerics, protection of 121
DDT suspected in fish
population reduction 209
Fish testing, contained DDT 210
I»DE, cflect on egg hatch-ability.
birds 212
DDE, effect on egg shells 212
HAWKS
Population decline of
Effect of DDT and dieldrin in
Eye contamination,
organophcjphates
211
212
665
Effect of DDT on population
Effect of Diddrin on
population 665
HAY
Fumigants, bromide residue in 198
Fed to cows, bromide in milk 198
HEADACHE
DDT, effects on humans 298
Acute pesticide intoxication 358
Organochlorinc intoxication 358
Acute DDT poisoning 359
Signs and symptoms of
intoxication, organophosphates 360
361
Acute inorganic arsenical
poisoning 362
Organic mercurial compounds 362
Poisoning symptoms 362
Oiganophosphonis compounds 367
Eye contamination 367
Poisoning with metaisosystox
414
138
-------
SUBJECT INDEX
Organc phosphorus poisoning
Cholinesteraie inhibitors
Mercury poisoning
Poisoning, symptoms
HEART
Fluoride rodenticides,
effect on
Occupational exposure to aldrin,
dieldrin, effect on
Diazinan poisoning, autopsy of
Yellov/ phosphorus ingestion.
effect on
Pesticides, poisoning
Hydr >gen cyanide, organism
tested, dose, effect
HEAT
Bacterial spores, resistant to
Physical pest control methods,
radiofrequency
Radiant energy, pest control
PCB s, in heat transfer agents
DDT, testing for sensations
Elemental pesticides, irritation
Nitrophenols, effect on heat
production mechanisms
Temperature effects, parathion,
sailn toxicity
HELICOPTER
Aerial spraying from
Needed engineering development
Needed engineering development
Aerial spraying
Application of pesticides from
Advantages, for applying
pesticides
Use for application of pesticides
Particle movement from
415
446
448
449
72
3S1
367
371
446
641
163
165
167
257
297
369
Mosquito control, use in
HEMATEMESIS
Yellow phosphorus, ingestion
HEMATOCRIT
Occupational exposure to
pesticides
Pesticide usage, correlations
HEMATOLOGIC
Studies to assess pesticide
effects
Needed support for research
Lindane, disorders
Lindane, disorders
Effects of pesticides
Exposure to pesticides
HEME
Research needs
Studies on hrme synthesis
HEMOGLOBIN
Pesticide usage
HEMOLYTIC
DDT, use in non-hemolytic
jaundice
HEMOPOIESIS
Research needs
Effects on, exposure to
pesticides
127
371
351
361
16
16
34
233
371
392
240
240
35!
245
240
240
433
533
23
23
102
102
105
106
106
106
Blood disorders, population
comparisons 372
HEMORRHAGE
Anticoagulant rodenticides,
death from 72
Gentian violet, effects 364
Nitrophenols, effects 370
Chlorinated hydrocarbons,
animal deaths 370
Organophosphorus compounds,
effects 371
Yellow- phosphorus ingestion 371
Paraquat, poisoning 373
139
-------
SUBJECT INDEX
Vitamin Kl.antidote
HEMOTOXICITY
Biood dyscrasias, chlordane,
gamma benzene hexachloride,
parathion
Pesticide exposure, discussion
of findings
HEPATIC
Research needs, detection of
effects of pesticides
Dieldrin, studies
DDT. effects on liver
microsomes
Paraquat poisoning
DDT, histological changes
Preemployment examinations
BHC ingestion, hepatic porphyria
Enzyme induction extra-hepatic
tissues, research needs
Enzyme induction
Research needs, enzyme induction,
extra-epatic tissues
Safrole, effects
3,4-benzpyrene. piperonyl
butoxide
HEPATOCARCINOGEN
Griseofuhrin
Safrole, tat
Freons, piperonyl butoxide
HEPATOMA
Griseofulvin, litter influence
Hydrazine, production of
hepatonus in mice
Mice, Freons, piperonyl
butoxide
HERBIODES
2,4-D, history
Pesticides after 1945
241
302
329
370
434
444
450
510
517
520
543
54*
485
543
545
485
492
545
44
46
4S1
388
392
241
302
329
370
434
444
450
510
517
520
543
54*
Number of chemicals, types
Contact
Systemic
Inorganic
Car joxylic aromatic
Phcnoxy
Betizoic acid
Phthalic acid
Phtiialamic acid
Aliphatic acid
Substituted phenol
Heterocyclic nitrogen
derivatives
Aliphatic organic nitrogen
Substituted ureas
Carbamates
Other amides
Dinitroaniline
Nitrite
Miscellaneous
Limited markets
Usage of, 1964
2,4-D; removal from water
Tentative guidelines
2,4-D; study
Water concentrations
Daily intake
In diet; 2,4-D; PCP
67
67
67
67
68
68
68
68
68
69
69
69
69
69
69
70
70
70
70
ao
104
123
124
126
128
135
136
Acceptable daily intake,
FAO-WHO 137
Usage, 1968, house and garden,
agriculture ! 147
Accidents, by industry,
by occupation 154
Drift of, in air 195
Granules, pellets, use of 199
Drift, reduction of 201
Effects on target, non-target
organisms 203
2,4-D 203
2,4,5-T, persistence 204
140
-------
SUBJECT INDEX
Use of
Paraquat
Diqutt
Poisonings, humans
Morbidity effects of
occupational exposure
Phenoxy chemicals, 2,4-D;
2,4.5-T
Nitrogen compounds, effects
Occupationally-related skin
conditions
Occupational exposure,
California
Effects of
Paraquat, effects
Tumorigenicity testing, ratings
Substituted urea . induction
of hepatic microsomal
erzymes
S true lure-activity-relation
Use in agriculture
Atratrone, experimental
Application form (H)
Chlorpropham
Endothall
Naptalam
PCP
Fkophftin
IRBTVORES
Solar energy, use by
Food web
DDT residues in
205
205
205
307
347
350
365
366
442
443
446
490
518
604
610
645
645
646
648
651
652
653
186
188
188
HERBS
Chemicals applied to 381
HISTOLOGIC
o,p'-DDD, effects, humans 301
Endrin studir, monkeys 410
DDT, DDE, effects in rats, sex
differences 428
DDT, effects 434
Changes, DDT, chlorinated
hydrocarbons 436
Pathologic evaluation 466
H1STOPATHOLOGY
DDT, rod-nts, liver 424
DDT, rats, liwr 434
DDT, monkeys, liver 435
HOARSENESS
Chronic arsenical poisoning 363
HOGS
Examination rf, for Sevin
residues 139
Storage of dieldnn in fat 265
HEOD in vs intake 279
HONEY
Bees, susceptibility to
carbaryl 208
Solvent for 2,4,5-T 666
Solvents for compounds 667
Solvent for compounds 674
HORMONES
Plant, research on 44
Juvenile 83
Juvenile 165
Developmental pheromones 219
Sex, effect on toxicity 428
Auxin analogs 604
HORNWORM
Tobacco pests, DDT control 89
Ught traps, effect on tobacco
hornwonn population 166
141
-------
SUBJECT INDEX
HORSE
Africa, Und, use of
91
Inhalation of pesticides
DDT, DDE in serum, comparison
263
HOUSEFLY
Resi?»i;ice to DDT, 1946
Disease vectors
Sterilization
Fate of MDP chemicals in
Metabolism of MDP compounds in
Metabolism of piperonyl
butoxide, tropital in
Metabolism of chemicals in
Metabolism in
HOUSEHOLD
Needed information on
exposure from UiS
Mcthoxychlor, use*.
Dieldrin, uses
Commercial pest control industry
Pyrcthrin. allethrin uses
Needed information on exposure
from use
DDT in meals
Excessive use, pesticides
Use of pesticides
Materials, to reduce pests
Usage
Safety precautions ignored
Use of, population groups
Commercial pest control
Insecticides for use
Incorrect disposal of containers
Storage of, protection of
children
Aerosols, inhalation of
59
164
164
548
549
549
555
560
23
51
52
53
63
102
114
132
145
146
147
148
149
150
151
159
160
201
with household dust
Pesticides, effects on skin
Insecticides, studies on
asthma, bronchitis,
sinusitis
Annual DDT plus DDE intake
DDT, DDE in diets
Haz.irdous Substances Act
Detergents, interaction with
pesticides, need for study
Enzyme induction studies
needed
Formulations, contain MDP
compounds
Detergents, interaction with
pesticides, need for study
Exposure to pesticides, tissue
residues
Exposure to pesticides
Use, synergist with pyrethrum,
control of pests
Use, need for mutagenic
evaluation
DDT, use
Dichlorvos, use
Lindane, use
^,
Paradichlorobenzene, u«
HUMAN
DDT, DDD, uses, evaluate for
health hazard
Body burden, residues, need
for surveillance of
Need for clearinghouse of data
Research support needed to assess
toxic effects
327
363
370
384
385
480
511
519
526
531
537
538
541
611
647
647
650
651
8
13
15
16
142
-------
SUBJECT INDEX
Needed regulations to protect
health IS
Lindane, need to discontinue
exposure 23
Controlled exposure 34
Organophosphates, residues 35
Control of diseases SO
Organochlorines, effects 56
Phthalamic acid cr npounds,
safety in 69
Carbamates, safety in 70
Rodrnticides, effects 71
Plant growth regulators.
toMcity 74
Parathion, deaths 81
Lindane, need to discontinue
exposure 102
Potential exposure hazards 112
Water route, exposure 123
Direct spraying 126
Systemic vs surface-type
pesticides, exposure 132
Time factor, residues in food 134
Residues in beef, consumption of 138
Endrin contaminated bread,
effects 158
Accidental incorporation of
pesticides in animal feed,
effects 159
Pesticides in food and feed 170
Pesticides in people 172
Antibiotics, effects 203
Viruses, pathogens, insect
control 217
Controlled exposure 233
Residues, disease 234
DDT, enzyme induction 235
Needed information, effects on
health 238
Action to improve protection
of public Health 239
Development of baits, reduction
of hazard 239
Pesticide protection teams,
reporting system for
poisonings 241
Epidemk>!ogjcal complexities 251
Single pesticide-single disease 254
General population studies 2SS
Case reports 256
PCB i, r.eed to examine tissues.
fluids 257
DDT administration 264
HEOD in 265
HEOD in 266
Organochlorites, adipose 269
p,p'-DDE in blood 273
Controlled exposures 295
Agent factors, pesticides
in poisonings 307
Host, pesticide poisonings 308
Pesticide residues 319
PCB s. adipose 320
DDT. DDE, adipose, blood 321
Djeldrin, DDT, residues,
sex differences 322
Socioeconomic differences,
residues 323
Time variable. DDT residues 325
Dietary sources, body
burden DDT 326
143
-------
SUBJECT INDEX
Monitoring survey, pesticide
residues in adipose
Monitoring data, pesticide
residues in adipose
Monitoring data, pesticide
residues in adipose
Monitoring data, DDE in adipose
DDT, dieldrin, adipose
DDT, dieldrin, adipose
p,p '-DDE, dieldrin.
DDT, adipose
p.p '-DDE, dieldrin, DDT,
adipose
Dieldrin, effects
Poisoning by pesticides
Residues, monitoring
Clinical case reports
Chlorinated hydrocarbon,
liver effects
Pesticides in milk
DDT in milk
DDT in milk
DDT in fat
DDT exposure, effects
DDT. foods, consumption
Paathion exposure,
decontamination of skin
Panthion hydrolysis
Percutaneous penetration studies
Radfolabekd materials, studies
Hair follicles, effect of
Fekema ES-30-9
DDT, DDE stoats
Captan, rnutagenicity
331
332
335
337
S38
339
340
341
349
356
357
358
372
373
374
385
387
390
39
400
401
402
404
405
429
438
Oir.'cal diagnostic techniques
Milk, pesticides in
Evaluation of carcinogenic
hazards
DDT carcinogenicity, need for
:nore research
Legislative needs
Monitoring survey
Intake of syncrgists, need for
further studies
Studies, organophosphates.
interactions
Dimetli^dtc degradation
Eiuyme induction methodology
needed
Residues of persistent
pesticides
Orfttnochlorines in tissues
Dieldrin, in diet
Phenobatbital, effect on
levels of •.hlorinated
'.ydrocarbons
Enzyme inducing agents, effect
on renducs
Factors determinun- storage
DDT in
Piperonyl butoxide. safe
toleruice for ingestion
MDP compounds metabolism
Dominant lethal test
Recommended program for
mutagenesis testing
Chemosterilants, exposure
Compounds known to alter DNA,
exposure to
Chlorinated hydrocarbons.
exposure
447
449
464
471
•180
496
511
512
514
520
525
526
528
529
530
537
538
542
547
596
603
604
605
610
144
-------
SUBJECT INDEX
Captan, embryo, mutagenicity
testing
HYDROXYLATION
639 Organophosphates in rats.
PCP, use in schistosomiasis
control
Expotuie to teratogen
Population monitoring
Studies
Chlorinated hydrocarbons in
mflk
Organophosphates, teratogenic
studies
HUMIDITY
Residues in environment
Fungi, conditions required for
insect pathogens
Environmental factors
Effect on toxicity, therapeutic
effect of chemicals
HUNGER
Pesticides, use to improve food
technology, production
DDT ingestion, condition of
human
HYBRID
Barley seeds
Strain of mice, effect of
2.4,5-Tin
Mice;2,4,5-Tin
HYDROLYSIS
Of orsanophosphites, on plants
Of pesticides, soil moisture
Of ndkriabded materials
Product of orguophosphates,
pwtropncnol
Of phospborylated oximes
Of bBrthrio, nta, rabbits
Of onanooh.>SDhates
652
€59
661
674
674
675
145
163
249
534
304
430
577
666
667
133
144
401
448
453
547
608
inhibition of testosterone
Metabolism of MDP compounds
Metabolism of MDP compounds
Metabolism of MD? compounds
HYGIENE
In industrial plants
Occupational exposure,
industrial hygiene
HYPERAcnvrrY
Barbiturates, to control
HYPERBARIC
Microsomal enzymes, effect of
oxygen exposure
Organophosphate poisoning.
use of hyperbaric oxygen
HYPEREMIA
Contamination of eye by
organophosphorus pesticides
HYPEREXCITABIIJTY
Chlorinated hydrocarbons,
poisoning symptoms
HYPERGLYCEM1A
Organophosphorus compounds,
changes found
HYPERPIGMENTATION
Phenoxy herbicides, 2.4-D,
2,4,5-T, occupational
exposure
Chlorinated acid derivatives.
occupational exposure
HYPERPYREHA <
Chlorophenols
HYPERSECRETION
Organophosphorus compounds,
poisoning, effect on
bronchial fluid secretion
HYPERSENSmVITY
Single pesticide, single
disease
DDT, fleets on
533
549
554
560
153
252
425
534
534
361
446
371
350
365
450
369
254
298
145
-------
SUBJECT INDF.X
Uncertainty in poisoning
diagnosis 449
HYPERTENSION
DDT residues, association with 329
Chlorinated hydrocarbons, effects
on cardiovascular system 370
Organophosphonis compounds,
effects 371
Pesticide residues in
Hazards to use
HYPOTHALAMUS
Brain centerf stress changes
in behavior
IMPURITY
feticides, technical grades
contain impurities
391
391
Poisoning, signs and symptoms 449
HYPERTHERMIA
Treatment of poisonings, use of
cold water 451
HYPERTROPHY
DDT, liver changes 434
HYPERBARIC
Mkrtsomal drug metabolism,
inhibited by hypoxia 534
HYPOPLASIA
Blood dyscrasia 388
HYPOTENSION
Organophosphorus compounds,
effects on cardiovascular
system 371
409
HYPOXIA
Mfcrosomal drug metabolism,
inhibition by hypobaric
hypoxia 534
249
Lindane. occupational exposure
to impurity in
(delta-heptachlnro-
cyclobexane) 363
Malathion sample, impure.
effects on cats, dogs
523
INCOORDINATION
Organic mercurial poisoning,
signs 362
Mercury poisoning, signs 448
INDUCTION
Of enzymes 305
Of enzymes, DDT, phenobarbital 329
Of enzymes, organophosptutes 348
Of enzymes, DDT 356
Of enzymes, DDT 357
Of enzymes, DDT, phenobarbital 434
Of enzymes, chlorinated
hydrocarbon pesticides 435
Of enzymes, chlordane 43*
Of tumors, judged positive,
judged negative 468
Of rumors, compounds judged
not positive 469
Of tumors, compounds judged
positive 47C
Of enzymes, needed tests for
pesticide studies S10
Of enzymes, pesticide
interactions 516
Of enzymes, types of chemicals
producing 517
Of enzymes, organophosphates 518
Of enzymes, tests for new
pesticides 519
Of enzymes, need for data 520
Of enzymes, chlorinated
hydrocarbons 521
Of enzymes, storage interactions 527
Of enzymes, DDT 528
Of enzymes DDT, phenobarbital 529
146
-------
SUBJECT INDEX
Of enzymes, effect on storage
Of enzymes, MDP compounds
Of enzymes
Of chromosome changes
Of dominant lethals, negatke,
captan
Of dominant lethals.
negative, DDT
Forward mutation, linuron
Recessive lethal, maleic
hydnzide
INFANTS
Pesticide poisonings in
Parathion ingestion by
DDT ingestton of, breast fed
DDT in
Age at start of experiments
Chlorinated hydrocarbons in
Mercurials, production of
infantile cerebral palsy
INFRARED
Use to control insects
INGESTION
By insects, stomach poisons
Modes of entry of pesticides
into body
Potable water supply
Limits, standards, pesticides
DDT, ODD, DDE, residues in
cow i milk
Accidents in children,
pesticides
Of pesticides, accidents in
children
Insect pathogens, ingestion
in food, water
S30
541
554
596
639
640
642
642
158
308
374
386
484
674
675
166
61
112
122
122
140
157
158
163
Of pesticides, epidemiologica!
complexities
Of pesticides, accidental
Case reports
Of chemicals, humans, in food,
dsinks
Of pesticides, routes of entry
Of organochlorines
OfHEOD
OfDDT.HEOD
OfHEOD, rats, concentration
m tissues
Controlled human exposures
Of DDT, experimental, humans
Of DDT, J.vmans, effect on lice
Of DDT, humans, effects
Of dieldrin, humans
Of pesticides, children, deaths
Of parathion, child
Of DDT, humans, time variable
Of organophosphates, effects
Of hexachlorobenzene. production
ofporphyria
Clinical case reports
Of organophosphorus compounds.
effect on gastrointestinal
system
Of inorganic anemcals, effects
Of thallium sulfate, children
Of hexachlorobenzene, humans.
effects
Of nitrophenols, effects
Of Paraquat, effects
250
251
256
262
263
264
265
267
284
296
297
298
299
302
306
308
324
347
350
358
361
362
363
364
368
370
147
-------
Of yellow phosphorus, effects
Of Paraquat, effects
Of chlordane, effects
Of Paraquat, effects
Of DDT, breast-fed children
Of pesticides, poisonings
Of DDT
Of aldrin, monkeys
Of poisons, children
Of DDT, humans, effects
Of pesticides, need for
protection
Of DDT. humans
Of BHC, humans
Of household detergents,
interaction with pesticides
Of pesticide residues
Of other chemicals, possible
interaction with piperonyl
butoxide
Of piperonyl butoxide, effects
Of pesticides, terting
Of pesticides, humans
Of pesticides, testing
INHALATION
Of pesticides, routes of entry
Of ak. DDT in
Of pesticides, occupational
exposure
Of pesticides, accidents
Of household pesticides
Of pesticides, case reports
Of pesticides, routes of entry
SUBJECT
37!
371
372
373
374
383
390
410
417
430
443
'47
450
526
537
541
542
567
611
657
112
114
153
158
201
256
263
INDEX
Of DOT. humans
Of DDT, humans
Of pesticides, clinical case
reports
Of nitrophcnols
Of pesticides, protection
Of DDT, humans
Of chemicals, evaluation of
carcinogenic rraards
Of pesticides, home owners,
need for legislation
Of synergists, effects,
information needed
Of MDP compounds
OfFreons
Of household pesticides, need
for mutagerucity studies
Of household pesticides,
need for mutagenic
evaluation of
INTERACTIONS
Little knowledge of
Need for study of
Of DDT and trichinosis, rats
Need for evaluation of DDT
with or by other materials
Summary of
Conclusions of
Definition of
Of pesticides, through
inhibition of esterases
Summary of
Of pesticides, through alteratii
nffi^miitf* micvo^nmst £iizi
w( ncjmiit* iiuuujwiiuu viicj
activity
Summary of
296
298
358
370
443
445
464
480
511
541
545
602
611
81
419
429
471
509
510
511
512
515
516
521
148
-------
SUBJECT INDEX
Of pesticides at target level 523
Summary of S24
Relation to tissue storage of
persistent pesticides S2S
Summary of 530
Exogenous physical factors
influencing pesticide
toxicity 531
Effect of diet 532
Effect of temperature 533
Effect of radiation 533
Other physical factors 534
Of pesticides with synergists 540
Of MDP compounds 546
Testing for, recommendations
for mutagenkity testing 603
Statistical analyses 668
INTESTINE
Experimental oral exposure
to methoxyrhlor 301
lUopsy of small intestine 301
Castro-intestinal effects of
organophosphorus compounds 361
'Paraquat, absorption from
intestine 370
EDTA. treatment of heavy
metal poisoning 451
delation in intestinal lumen,
oral administration 451
Interactions, by interference
with intestinal absorption 511
Organochlorine compounds,
effect of fat diet on
absorption from intestines 530
Effect of fat diet on toxicity
of benzene hexachkmde,
absorption from intestines,
rats 532
INTRAMUSCULAR
Poisoning by heavy metal
derivatives 4S1
Dimercaprol, IM. in treatment
of poisonings 452
EDTA, IM. in treatment
of poisonings 452
INTRAPERITONEALLY
Treatment of carbamite
poisoning 410
MDP compounds, route? of
administration 544
Mutaton studies, host
mrdiated assay 594
INTRAUTERINE
Tests for; malformations 600
INTRAVENOUS
Study of chemicals, metabolites 403
Injec'ion of acety Icholine,
we in schizophrenics 413
Injection of parathion, effect
of temperature on toxicity.
mite 432
Of EDTA, treatment of heavy
n> - tal poisonings 452
Injection of MDP synergists,
rats 543
Injection of MDP compounds,
with 3,4-benzypyreiie 544
Injection of MDP compounds,
metabolites in urine,
rats 547
INTUBATION
Route of administration 483
Oral intubation, repeated doses 484
Oral route, maternal metabolism 486
IRRADIATION
Sterility induced by 164
Sterilization, induced by 166
149
-------
SUBJECT INDEX
Exposure of rats to
X-inadution 533
Chromosome studies 587
Dominant lethal test 596
JAUNDICE
DDT, use in treatment of
unconjugated
non-hemolytic jaundice 24S
DDT, use in 300
Yellow phosphorus ingestion,
effects 371
DDT, use of in treatment of
unconjugated nonhemolytic
jaundice 436
JUVENILE
Hormone, effect on insect
reproduction 83
Hormone, sterilization of
insects 165
Precautions for use 16S
Hormone, uses, precaution* 219
KERATIN
Propellants in pesticide
aero«ol dispensers.
cornea! injury 368
Pesticides, effect on 405
KIDNEY
Pesticides, effect on fish 210
Function, pesticide exposure 351
Ingestion of yellow phosphorus 371
Chlorinated hydrocarbons,
effects 373
Panthion metabolism, humans 430
DDT in, starvation 431
Captan. effects on 438
Chlorinated hydrocarbons,
effects 447
Research needed, enzyme
induction 510
Research needed, enzyme
induction 520
Chlorinated hydrocarbons in 536
2,4,5-T; production of
cystic kidneys, mice, rats 666
KILLS
Pyrethrum, use against insects 44
HCN, effect on red scale insect 45
Stomach poisons, effect
on insects 61
Rotenone, mode of action 63
Contact herbicides, mode of
action 67
Aliphatic acid herbicides, uses 69
Nematocides 70
Thiophcne nematocides, mode
of action . 71
Rotenone, effect on fish 73
Toxaphenc, effect on fish 73
Labeling of pesticides 76
Biological control, scale
insects 82
Residues in animal tissues 138
Commercial pest control 152
Endrin contaminated bread,
effect on rat 158
Pesticide treatment, goals 161
Insect pathogens 163
Juvenile hormone, rffects 165
Radiofrequcncy electromagnetic
energy 165
High intensity «?nic, ultrasonic
energy, effect on pests 167
150
-------
SUBJECT INDEX
Repellants, toxicants, effect
on mice 200
Herbicides, effect on i.ontarget
organisms 203
Plant growth regulators 205
Insecticides and miticides 206
Dieldrin, effect on fish, crabs 209
DDT, effect on crabs 209
Baytex, endrin. effect on
crab larvae 209
Fish 210
Rodenticides, effect on cats 214
Avicides 214
Soil preparation, effect on
insects 218
DDT ingcstion, human, effect
on lice 298
Accidental deaths, residues in
humans, ethnic differences 322
DDT residues in humans 329
Chlorinated hydrocarbons,
animals, symptoms, effects 370
Parathion ingestion, children 428
BUdR, effect on Chinese
hamster cells S88
Bipyridylium quaternary salts,
effect on plants 607
KITTENS
DDT. DDE blood lewis in 1'8
LACRIMATION
Organophosphates, signs and
symptoms of intoxication 360
LAKES
DDT. DDE metabolites in 9
Contamination by DDT 13
Use of rotenone to kill
undesirable fish 73
Pesticides, run-off into 116
Pesticides in Lake Michigan 119
Pesticides in, endrin in 125
ODD application to 126
Needed studies of pesticides in 169
Need for monitoring of 171
Application of pesticides,
avoidance of 196
Contamination of by Dinoseb,
effects on aquatic organisms 203
Trout in, effect of DDT on 209
Toxaphene, use in, effects 213
LAMBS
Dieldrin, residues in 265
Concentration of dieldrin in
fat, vs concentration in diet 279
LAMPREY
Baytuscide, to control 72
Lampricide L-30-F, to control
lamprey populations 73
LAPAROTOMY
Embryo's obtained by ... 661
LARVAE
Aldrin, use to control com
rootworm larvae 52
Control, Department of Defense 54
Mosquito, use of Abate as
replacement for DDT 60
f
Coiton crops, use of
cyclodiencs to control 84
Cereal crops, use of BHC 86
Oil seeds, use of toxaphene 90
Bndworm; particle axe. effects 111
Mosquito; 2,4-D effect on 126
Control of alfalfa caterpillar 163
X-rays, gamma rays, effect on 167
1S1
-------
SUBJECT I\OEX
Organochlorines, effect on
marine invertebrates 208
Blue crabs, effect of DDT on 209
Trichina, effect olDDT. rats 430
LARVICIDE
Pesticides before 1945 44
Petroleum oils, use as 44
DDT, use as 48
LAWNS
Needed information on exposure
to pesticides used for 23
Dieldrin, use foi insect
control on
Chlordane, uses on
Herbicides, uses on
Metal-organic compounds, uses
Needed information on exposure
Commercial services, use on
Granules, use of by homeowners
2,4-D, use on
LD-50
Acute, definition of
Dermal, indicative of human
poisoning
Acute oral, phosphate ester
pesticides
Acute dermal, phosphate ester
pesticides
Acute oral, chlorinated
hvdnwfann twcficufec
iijrtH^AiviiMjit I^BUVMBO
Acute dermal, chlorinated
Hydrocarbon pesticides
Of pesticides
SJrfo
Effect of DMSO on Seman
Carbamates
52
53
67
68
102
197
199
646
259
307
312
312
313
313
382
402
403
410
Acute dermal, occupational
poisoning vs acute oral 423
Of pesticides 425
Acute oral. DDT, rats 428
Hale vs female rats 429
Dermal, dieldrin, rats 430
Useof atropinc in
cholinesterase poisoning 452
Use of oximes in poisonings 453
Use of tetraethylammonium
chloride in carbamate
poisonings 454
Organoptiosphates 518
Effect of 1'iet on 532
Oral toxicity of pesticides 645
Oral toxicity of pesticide \ M6
Oral toxicity of pesticides 647
Oral toxicity of pesticides 648
Oral loxitity of pesticides 649
Oral toxicity of pesticides 650
Oral toxicity of pesticides 651
Oral toxicity of pesticides 65 2
Oral toxicity of pesticides 653
Teratogenicity testing 660
LEGUMES
Chlorinated hydrocarbon
pesticides, dietary
intake from 135
Residues of herbicides in 137
Crop rotation 218
LESIONS
Difolatan, occupational
exposure 365
lOpafbx, neuron*! 413
Pesticides, neurological 413
152
-------
SUBJECT INDEX
Liver, DDT. chlorinated
hydrocarbons 435
Testing procedures.
carcinogenic hazards 465
Characteristics of
carcinogenicity 478
Piperonyl butoxide, effects in
livers, animals S42
Chromosome effects 592
LETHAL
Pesticides, effects on humans 113
Use of radiofrequency, effects
on insects 166
Effects on marine life 210
Dieldrin, DDT, studies in
birds 212
Genetic manipulation of
pest populations 219
LD-SO definition 2S9
Warfarin, effect of temperature
on toxicity 433
Mutations, effects 569
Plants, effects, detection
in microspores or pollen 575
Mutation induction by
seed treatment 576
Drosophila, testing for
mutations 586
Dominant lethal test 596
Summary of mutagenicity
testing 601
Recommended program for
mutagenicity testing 602
Captan, negative induction
of dominant lethals 639
DDT. negative induction of
dominant lethals 640
Formaldehyde, low incidence
of recessive lethals 641
Maleic hydnzide (MH), no
recessive lethal induction 642
LETHARGY
o,p -ODD, effects in humans 301
LEUKEMIA
Radiation exposure, effects 255
National Death Index,
etiologies of 498
LEUKOPENIA
Blood dyscrasias, pesticides
associated with 388
LICE
DDT ingestion, human, effect
on Ike 298
Parathio^, use as treatment for 311
Chlorinated hydrocarbons 363
Lklane, use for control of 363
LIPID
Model, use of in study of
dynamics 271
Metabolism of, in fat cell,
interpretation of 272
Metabolism of fipid-soluble
compounds, different animals 426
DDT, toxicity, effxt of fat
in diet 431
Dieldrin, effect of dietary
protein 432
DPT, formation of inclusion
bodies 434
Sesame oil, use as lipid
vehicle in cancer research 543
LIVER
Orgmochlorines, effect on 33
Enzyme induction, DDT 36
Effect on, pesticides, fish 210
153
-------
SUBJECT INDEX
Enzyme induction. DDT 235
Enzyme induction, DDT 246
Presence of pesticides in 248
Cod liver ofl, analy sis 25 7
Cancer, occurrence 262
Dieldrin in correlation with
blood levels 267
HEOD in. rats 269
HEOD in, rats vs concentration
in blood 285
HEOD in, rats, during
post exposure period 293
Function tests. DDT exposure.
humans 299
DDT, use to decrease scrum
bilirubin 300
o.p-DDD exposure, humans 301
Mcthoxychlor exposure, humans 301
Pesticide levels and disease 329
Residues of DDT 329
Organophosphates, chronic
exposure 348
Function tests, pesticide
exposure 351
Ingcstion of yellow phosphorus.
effects 371
Chlorinated hydrocarbons. DDT.
effects 372
Organophosphorus compounds,
effects 373
Pesticides in body tissues 385
Enzyme induction, pesticide
exposures 388
Cirrhosis of. pesticide levelt 391
Disease, organochloride
pesticides in 391
PesticiJe exposure, behavioral
changes 409
DDT, effects on, rodents 424
Chlorinated hydrocarbons, DDT.
effects on, rodents 425
Azinphosmethyl metabolism 426
Microsomal activity, neonates 427
Cell morphology, DDT, sex
differences 428
Metabolism of Azinphosmethyl
and EPN. sex differences,
rodents 428
Damage by carbon tetrachloridc,
effect on methoxychlor
toxicity 430
Microscmal activity, starvation 431
Storage of DDT, rats, starvation 431
DDT, effect on storage of
Vitamin A 432
Chlorinated hydrocarbons,
effect on 434
Chlorinated hydrocarbons, DDT.
effect on, rats 435
Chlorinated hydrocarbons,
effect on weight, fat
content 435
Induction of microsomal
enzymes 435
Microsomal enzyme changes.
structural changes 436
Chlorinated hydrocarbons,
effects 447
/
2.4-D; 2.4.5-T effects on 450
Anticoagulant rodentitides,
effect on 451
Enzymes, newborn mice vs
adult mice 484
Organochlorines in, disease
vs controls 495
Cancer 497
154
-------
SUBJECT INDEX
Enzyme induction
Alicstcrase, studies needed
for anticholincsterase
pesticides
Aliesterase, metabolism of
parathion
Aliesterase. need for studies
Enzyme induction
Enzyme induction
Enzyme induction, chlorinated
hydrocarbons
Chlorinated hydrocarbons.
enzyme induction
Enzyme induction
Enzyme induction
Enzyme induction, MDP compounds
Pyrethrum, effects on, rats
Microsomcs, metabolism of
MDP compounds
Microsomal mixed function
oxidases
Microsomal enzymes, metabolism
of MDP compounds
MDP compounds, tffec: on
microsomes
LIVESTOCK
New pesticides, uses
Botanical insecticides.
rotenonc, uses
i
Miscellaneous insecticide
compounds, fly sprays, uses
TEPP, spraying, effect on
Accidental incorporation of
pestkides in animal feed
Pesticides in food and feed
Use of pesticides
S09
S13
514
514
517
520
524
527
530
533
541
544
548
554
555
560
59
63
65
110
159
170
196
Hazard to. cereal seed
dressuigs. treated
DicMorvos, u
-------
SUBJECT INDEX
Population studies, comparison 372
MOP compounds, tumors of 543
LYMPHOMA
Piperonyl butoxide, mice 492
National Death Index 498
MAGGOT
Aldrin for control of 651
MAIZE
Cereals 85
BHC for control of pests 85
Losses due to insects 87
Mutation induction by
seed treatment 577
Locus in. determination of 578
MALAISE
DDT, effects 298
DDT, in treatment of jaundice 300
Organochlorines, chronic
poisoning 358
Chlorinated hydrocarbons 359
DDT poisoning, symptoms 359
Anticholinestenses, effects
in humans 411
MALARIA
DDT, use in control of 9
DDT, use in control of 21
DDT, use in control of 43
DDT, persistence, use in
control of 49
DDT. use in control of 91
Dieldrin, use in 91
DDT, use in control of 104
DDT, use in control of 296
Baygon, use to control, effects 416
DDT. use to control 472
MALLARD
Residues in ducks 171
DDE, effect on reproduction in
ducks 209
DDE. effects on reproduction in
ducks 212
MAMMARY
Freons. piperonyl butoxide,
carcinoma 545
MANIA
Organophosphates, behavioral
changes 410
MARINE
Inhibition of algal
photosynthesis, DDT 121
Monitoring of pesticides in,
organisms 129
Application of pesticide to
prevent attack by 197
Invertebrates, pesticides in 208
Life, effects of pesticides on 210
Environment, production
of seafood 220
MARROW
Population studies 255
o,p'DDD, examination of
bone marrow 301
Oral exposure to methoxychlor,
humans 301
Biopsy of bone marrow 301
Bone marrow, useful for in
vivo testing 589
MATERNAL
Metabolism, offer i of oral
intubation route 484
Metabolism, oral intubation
route 487
Methodologies for
teratogenicity testing 659
Use of techniques to measure
body burden of
suspected chemicals 663
156
-------
Methods, statistical analysis
Chlorinated hydrocarbons, DDT,
DDE, transplacental
passage of, study of
spontaneous abortion
MATING
Environmental control, insects
Juvenile hormones, effects
Dominant lethal test, rodents
Methods, teratogenicity testing
MATURE
Drug metabolizing enzyme
system in animals
Pollen abortion in flowers
Cytogenetics, somatic cell
genetics
MAYFLY
2,4-D. effects on
MEAT
Delaney clause, effect on
Chlorinated hydrocarbon
pesticide n.-sidues in
Herbicides, residues in
Residues in
Accidental incorporation of
pesticides in animal
feed, residues in
Pesticides in food and feed
Residues in humans,
consumption of
Pesticide residues from
Pesticide residues from
MEIOSIS
Atrazine, effect on
Carbaryl, effect on
DCNA, effect on
Dicamba, effect on
Endrin, effect on
tsocil, effect on
SUBJECT
667
675
164
165
5%
667
426
578
587
126
14
136
136
138
159
170
320
385
537
639
639
640
640
640
£A 1
INDEX
Linuton, effect on
Monuron, effect on
Naptalam, effect on
Phosphamidon, effect on
Simazine, effect on
MELANOGASTER
Formaldehyde, effect on
Drosopbila
Maleic hyUrazide, effect on
Drosophila
MELLITUS
Diabetes, DDT exposure.
humans
MELON
Insect attractants, use to
control melon flies
Eradication programs for
melon flies
.MENTAL
Organophcsphatcs, effects
Behavioral toxicity,
definition
Anticholistrose compounds.
effects
FAA workers, exposure to
pesticides, effects
Phosdrin and/or Parathion
exposure, human, effects
Organophosphorus compounds.
effects
MESOTHEUOMA
Asbestos, complication of
METABOLISM
DDT. metabolitics, distribution
in environment
Needed support for research
Of heptachlor. heptachlor
epoxide
Fungicides and bactericides
Reeulators of plant growth
642
642
643
643
643
641
642
391
75
164
389
407
411
414
417
419
254
9
16
52
65
74
157
-------
SUBJrCT INDEX
Of Zectran, by sunlight,
plants, animals
.
Of pesticides by plants
Of Guthion, metabolites in
cow s milk
Products, detection of
Pesticides, effects in fish
Of steroids, effect on
reproduction
Research needs „
Toxicological complexities
Needed knowledge in
Of DDT
Of DDT, measurement of DDA
Of DDT, ODD
Of DDT
Of DDT
Of DDT, adipose levels
Of DDT, sex differences
Of DDT, levels, effect of
phenobarbital.
phenytoin on
Of parathion, paranilrophuiol
Organophosphorus compounds.
effects on genito-urinary
system
Of paratliion, paranitrophenol
Of DDT. humans
Of pesticides, skin, needed
information
Of pesticides
Sample skin matrix
Of Guthion
111
133
140
172
210
211
. 240
246
255
268
298
300
319
320
321
322
323
347
373
388
390
401
402
405
426
In newborn animals
Of DDT, storage of, metabolites
Dicldrin, interaction.
unsaturated fatty acids
Of DDT, DDA formation
Of parathion
Of hcptachlor, heptachlor
epoxide
Of chemicals, effect of dosage
Of cL.ylcarbamate (uret>.an)
Need for studies on drug
metabolism, different
species
Drug metabolizing enzymes
Chemicals, effect on
Pesticides, effect on
Enzymes, effect of chlordane on
Enzymes, effect of
hcxot rbitalon
Research needed, drug
metabolism, various species
Research needed, toxicity.
metabc'
-------
SUBJECT INDEX
Of chemicals, effect of other
physical factors 534
Of chemicals, effect on storage 536
Residues, effects on S39
Enzyme induction 540
MDP compounds, effect on 541
Oi 3,4-benzpyrene 544
Of MDP compounds 547
Of MDP compounds 548
Of MDP compounds 549
Of piperonyl butoxMe, mammals 552
Of tiopital, mammals 553
Of MDP compounds 555
Mutagenicity testing,
Neuiospora 573
Mutagenicity testing.
metabolic products 589
Host-mediated assay 594
Metabolic inhibitors,
structure activity
relationship 604
Of chemicals, tentogenicity 658
METAMORPHOSING
Juvenile hormones, production
of during 165
Organochlorine insecticides,
effects 208
METAPHASE
Preparations, for testing 589
Examination of ce!b during 593
METASTASIZE
Malignant tumors 466
Animal tumors 466
MICE
DDT, pest control 54
Inorganic rodenticides 71
Miscellaneous rodenticides 72
Pests 150
Repellents, use 200
DDT, carcinogenic in 357
Norbormide, effects in 426
Ethyl fenthion, toxicity 429
Parathior., toxicity, effect
of mice 432
Testing procedures, animals 465
DDT, carcinogenicily in mice 471
Tumorigcnicity testing in • 473
Tumorigenicity testing in 474
Tumorigcnicity testing in 475
Testing in 481
Testing in, carcinogenkity 483
Persistence of DMBA in 484
Piperonyl jutoxidc in 492
Organic phosphates in 518
Sesame oil, effects in 543
Freons, effects in 545
Coumaphos, effects in 546
Myristicin, metabolism in 548
Inhibition of enzyme
systems in 554
Host-mediated assay 594
Specific locus test 595
Dominant lethal test 597
TEPA. METEPA, mutagenic
threshold in 598
Captaa, mutagenicity testing in 639
DDT, mutagenicity testing in 639
159
-------
MH mutagenicity testing iir
Tumorigcnieity testing, species
Captan, folpct
Organophosphates, effects in
2.4,5-T. effects in
Testing for increase anomalies
Testing for increase anomalies
Testing for increase anomalies
MICROBIAL
Control of insect pests
Fungicides and bactericides
Soil moisture, effects
Insect pathogens
2,4-D; effects
2.4.5T; effects
Mutagenicity testing
Mutagenic activity in
MICROORGANISM
Definition of pesticide
Sofl moisture, effect on
degradation by
2,4-D; decomposition by
soil microorganisms
Degradation of 2,4-D. MCPA.
and2,4,5-Tbysofl
microorganisms
2,4,5-T application to soil,
effect on microorganisms
Nematocide, effects on
Mil microorganisms
Host mediated assay
MILK
DeUney clause, effects on
Heptachlor, residues in milk
Carbamates, excretion in
SUBJECT
642
6S9
664
665
666
670
671
672
60
65
144
163
203
204
572
595
44
144
203
203
204
205
594
14
53
64
\KDEX
Milky disease, biological
control
DDT residues in, cow's milk
Residues in cow's milk
Bromide residues in cow's milk
Milky disease
Food additive, hydrogen
peroxide, used for
preservation of
Human milk, PCB in
Organochlorines in
Pesticides in human mflk
Human milk, DDT-derhred
materials in
DDT ingestion, infants
DDT in, human, cows
DDT in, human milk
Human milk, residues in
Pesticides in human milk
MINAMATA
Disease, malformations induced
by
Mercurials
Disease, production of
MISCARRIAGE
Mutagenicity
MITES
Oils, use to control
Cotton crops, chlorinated
hydrocarbons, use to control
2,4-D; effect on
Insecticides and miticides
Beneficial insects
Fertilizers, spider mite:
Parathion, use to control
82
139
140
198
217
244
258
269
373
374
374
385
437
449
674
661
675
675
569
62
84
204
206
207
218
652
160
-------
Phosphamidon, use to control
MTTIC1DES
Insecticides and miticides
Synthetic organic insecticides
and miticides
Insecticides and miticides
Application (M) miticide
MITOSIS
Mammalian methods
Examination of cells
Carbaryl. effect on
Chloroform, effect on
2,4-D, effect on
DDT, effect on
Dieldrin. effect on
Lindane, effect on
Maleic hydrazide, effect on
Paradichlorobenzene, effect on
Parathion, effect on
MOISTURE
Factors influencing changing
use patterns
Factors, soil contamination
SoO moisture and temperature
Wind erosion
Bacteria, resistance to
Persistence of 2,4-D
Nematocides and so!l fumigants
MOLLUSCICIDE
Invertebrate poisons, used to
control moJhisc*
Toxicity to fish
Toxicity to warm-blooded
animals
Pentachlorophenol. used to
control molluscs
SUBJECT
653
61
63
206
645
587
593
639
639
639
640
640
641
642
643
643
58
143
144
145
163
203
205
72
72
72
6S2
INDEX
MONGOOSE
Biological control,
introduction to control tats
Use for rat control
MONKEYS
DDT administration to
DDT excretion
DDT residues in
DDT in body fat vs diet
DDT in bodyfat vs
continuous exposure
DDT in bodyfat after exposure
terminated
DDT. DDA in vs daily dose
Endrin in, effects
Metabolism of DDT. DDE
Metabolism of pesticides in
DDT storage
Sarin toxicity, effect of
temperature
DDT, liver effects
Sarin toxicity, effect of
temperature
Piperonyl butoxide toxicity
Captan. tentogenic studies
MORBIDITY
Pesticide related
Studiss
Epidemiologic studies
Pesticides, diseases
Epidemiological approach.
human effects
Tata extrapolation
Studies, case reports
82
216
264
268
272
277
282
286
289
410
424
427
423
432
435
533
542
664
237
251
252
253
295
307
344
161
-------
SUBJECT INDEX
Effects of occupational
exposure 345
Specific conditions, blood
dyscrasias 388
General measures of 390
MOTHPROOFING
Exposure, humans ISO
Wearing of clothing treated
with pesticides ISO
Study of dry-cleaning firms ISO
Chemicals used ISO
Exposure to DDT ISO
MUCOSA
Organophosphorus compounds,
effect on intestinal mucovj 361
Nitrogen-containing pesticides 370
Paraquat ingestion. effects 370
MUSCULAR
Inorganic arsenical:, muscular
cramping, symptoms of
poisoning 362
Anticholinesterases,
administration, humans 411
Muscular aches and pains 411
Organophosphorus agent 411
Low doses, effects 411
Metaisosyctox, symptoms of
poisoning 414
Organophosphorus compounds,
effects 416
MUTAGENS
Chemicals proposed for insect
sterilization 83
Chemosterilants 164
Research studies needed,
animals, mutagcnesis 241
Alkylating agents 261
Captan. effects in bacteria 438
Interactions 515
Mutagenicity of pesticides 567
Mutagenicity as public
health hazard 568
Ejects 570
Information needed on
mutagenicity 571
Methodologies for mutagenicity
testing 572
Bacterial 572
Neurospora, mutations in 573
Phage and transformation 574
Plants, mutations in 575
Mutation induction by seed
treatment 576
Root tip method for
chromosome aberrations 577
Somatic mutation methods 577
Specific-locus method (waxy
locus) in poDen 578
Summary, methods used for
detecting 582
Mutations, chemicals producing 583
Mutations, chemicals producing . 584
Mutations in barley 584
Mutations, chemicals producing 585
Drosophila, mutations in 585
Cytogenctics and somatic ceQ
genetics 587
Chemicals producing 591
Host-mediated assay 594
Specific ltx.-us test 595
Potent mutagenic compounds 595
Dominant lethal test 596
Population monitoring 599
Summary, mutations' 601
Recommended program for
testing 602
162
-------
Smicture-tctivhy-relations
Aticylating agents, effects
Mercurials, effects
Testing
MYOCARDITIS
Organophosphonis compounds,
acute toxic myocarditis
Paraquat ingestion, myocarditis
NAILS
Paraquat, diquat, effects on
Paraquat, diquat, effects on
Needed observations on, as
index of toxicity
Sample skin matrix
NARCISSUS
2.4-D. effect on
Ethylmercury chloride, use
to treat bulbs
NARCOLEPTIC
Sleep patterns
NASAL
Allergy, pesticide exposure
DDT. effect on nasal vibrissae
Congestion
Perforation of nasal septum
chronic arsenical poisoning
Irritation from
2-chlorophenylphenate and
sodium orthophenyl phenate
/
NAUSEA
Organochlorines, effects
Organophosphates, effects
Organophosphates
Arsenical poisoning
Yellow phosphorus
SUBJECT
604
606
608
639
371
371
365
405
405
405
639
649
416
148
296
361
363
370
370
301
358
360
361
362
371
INDEX
Chlorinated hydrocarbons,
effects
Poisoning symptoms
Cholinesterasc inhibitors.
effect*
NECK
Chlorinated acid derivatives,
2.4-D; 2,4,5-T occupational
exposure, hyperpigmentation
Organophosphorus compounds.
precautions
NECROSIS
Paraquat, over effects
DDT. lim effects
DDT. livir effects
NEMATOCIOE
Halogens :ed hydrocarbons
Organic phosphates
Oyanates
Thiophenes
Volatile liquids, gases
And soil famiganls
Chlorinated aliphatics, effects
Chlorinated aliphatics
Mode of action
Application form(N)
NEMATODE
Biological control
Nematocides
Kalogeiu*ed hydrocarbons.
effects
Organic phosphates, effects
Cyanates, effects
Thiophenes, effects
Insect pats, predators
Insect pathogens
Volatile liquids, gases,
control of
446
449
450
365
444
373
434
435
71
71
71
71
198
205
367
369
604
645
60
70
71
71
71
71
162
163
198
163
-------
Barriers, application of
Pathogens
Water management, effect on
NEONATAL
Toxicity testing and
carcinogeniciiy testing
using
Non-human primates,
teratogenicity testing
Body burden, need for study
NEOPLASM
Lindane, effects, comparison
with other populations
Storage of DDT, DDE in humans
Tumors, as end points of study
Testing of chemicals for
benign, malignant neoplasms
NERVE
Pyrcthrin, allethrin.
effects on
Chlorinated hydrocarbons,
effect on
Isopestox. effect on
Organophosphates, effect on
DDT, effect on
Classified oiganophosphorus
agent, effect on
Organophosphates, effect on
Otolinesterase agents, effects
NEURITIS
Chronic arsenical poisoning,
signs and symptoms of
Thallotoxicosii, signs.
symptoms
Chlorinated phenols, effects
Metallic derivatives
Organic mercurial pesticides.
effects
SUBJECT
199
216
213
485
661
V663
372
430
482
482
63
359
360
369
408
411
419
452
362
363
367
368
368
INDEX
2,4-D, production of
peripheral neuritis
Mipafox, production of
peripheral neuritis
NEUROLOGIC
Experimental respiratory
exposure to DDT
DDT, exposure, humans
Occupational exposure.
pesticides
Thallotoxicosis, symptoms
Abnormalities
DDT exposure, humans
i
'•Occupational exposure
Chlorinated hydrocarbons,
effects
Pesticide, effects
NEUROMUSCULAR
Parathion effect on
ncuromuscular system
Organophosphates, effect on
nervous system
Organophosphorus compounds
Effects on respiration
DDT, effects on ncuromuscular
system
Chlorinated hydrocarbons.
effecb on ncuromuscular
system
Attopine, effect on NMJ
EPN, malathion, effects on NMJ
Structure-activity
relationships
Inhibitors of NMJ
NEUROPATHY
Hazards from exposure
Mipafox, peripheral neuropathy
Chlorinated phcnoxy acid
compounds
2,4-D, peripheral neuropathy
406
416
296
299
351
363
389
391
394
408
413
206
206
369
369
425
425
452
523
604
604
261
360
362
362
164
-------
SUBJECT INDEX
NEUROSPORA
Crassa, metabolism, different
from mammals 573
Testing for mutations in S8S
Use in tests 594
Fumigants, mu tations in 611
Ethylene chlorohydrin,
mutations in 611
Organophosphate insecticides,
mutations in 611
Ethylene oxide, mutations in 640
NEUROTOXIC
Parathion. malathion, isopestox 360
Pathology, exposure to
pesticides 433
NONCARC1NOGENIC
Substitutes for agents 478
NONTOXIC
Phthalic acid herbicides,
effect on mammals 68
Botanical rodenticides,
effects on other
warm-blooded animals 72
Miscellaneous rodenticides 72
Norbormide, effects on other
warmblooded animals 72
Molluscicides, effects on fish,
effects on warm blooded
animals 72
Plant growth regulators, effects
on humans, other warm-blooded
animals 73
Repellents, effects of 215
NOSE
Respiratory exposure to DDT,
humans, experimental 296
Carbamates and dithiocarbamates,
irritation of nose 369
Areas of exposure 407
Cholinesterase inhibitors,
effects on 446
NOSEBLEED
Gentian violet, effects 368
2-chlorophenylphcnate and
scdium orthophcnylphenate,
effects 370
NURSERY
Orga,iochlorines, uses 55
Nitrite herbicides, uses 70
Estuarinc areas, marine food
production 121
Pentachlorophcnol, linens 311
NUTRITION
Fertilizers, host plant, effects 218
Research needs, states, effects
on pesticide responses 240
Infants, DDT ingestion 374
Effect on DDT residues 388
FacUxs affecting responses 426
Effcc. on pesticides 431
Effect on storage 530
Diet, effect on toxicity 532
NUTS
Fumigants containing bromine,
residue entering crops 198
Piperonyl butoxide, uses 542
Acrytonitrile, uses ' 645
Ferbam, uses 649
Simazine, uses 653
NYSTAGMUS
Organophosphorus compounds,
chronic exposure of pilots to 414
OAK
Poison oak, contact dermatitis 398
OATS
Losses due to insects 86
165
-------
SUBJECT INDEX
Heptachlor and heptachlor
epoxide, residues in
Aldiin and dielctiin, residues in
Resistant strains of plants
Propham, uses
OBESITY
Occupational exposure to
pesticides, effects
2,4-dimtrophenoI, use to
treat
Cataracts from 2,4-dinitrophenol
OCCUPATIONAL
Lindane, exposure vs home
exposure
Exposure, pesticides,
accidents
Exposure, accidents, pesticides
Exposure, accidents
Exposure, humans
Exposure, pesticides
Exposure, needed surveillance.
clinical testing
Exposure, studies of
Exposure, studies of
Exposure, diseases
Exposure, diseases
Exposure, general population
studies
Exposure, case reports
Exposure, studies of groups
Exposure
Exposure, routes of entry
Exposure, dktdrin
Exposure, adults
Exposure, reporting of
Exposure, epidemiology of
133
133
162
653
351
368
368
149
152
157
158
172
234
242
251
252
253
254
255
256
256
260
263
302
306
307
pesticide poisoning
Exposure, epidimiological
studies
Exposure, DDT residues
Exposure
Exposure, mortality studies
Exposure, morbidity effects
Exposure, carbamates
Exposure, diene group
Exposure, chlorinated
hydrocarbons
Exposure, phenoxy chemicals
Exposure, effects
Exposure
Exposure, skin effects
Exposure, dermatitis
Exposure, dermatitis, captan
Exposure, skin conditions
Exposure, chlorinated
hydrocarbons, effect on
cardiovascular system
Exposure
Exposure
Exposure, DDT
Exposure
Exposure, hazards of current
pesticide use
Exposure, DDT
Exposure
Exposure, needed studies
Health specialists, survey
Exposure, poisonings, effects
314
319
324
327
344
345
348
349
3:0
350
351
356
363
364
365
366
370
383
385
386
389
392
393
394
395
415
416
166
-------
SUBJECT INDEX
Exposure, poisoning, relationship
to, acute dermal LD-50 423
Exposure, effects
Exposure, DDT
Exposure, surveillance of
Exposure, evaluation of
carcinogenic hazards
Exposure, legislative needs
Exposure
Exposure, interactions
Exposure, cholinestcrasc
inhibition
Exposure, chlorinated
hydrocarbons
Exposure, interactions
Exposure
Exposure. DDT
OCEANS
DDT in
DDT contamination of
Pesticides in, need for data
Pesticides in
Need to study pesticides in
Pesticides in surface waters
CDOR
Chlordanc, low odor, properties 151
DDT, solutions of
Intolerance of pesticides
Psychogenic odor
ODORLLSS
Anticoagulant rodcnticidcs,
properties
Fluorine rodcnticidcs.
properties
Suspensions of DDT, properties 298
Lindane, crystals, properties 650
OIL
442
447
454
464
480
496
509
514
521
526
527
538
9
13
23
101
169
171
151
298
415
418
72
72
298
Use before 1945
Insecticides, uses
Of poison ivy, effects
Seeds, use of BHC, chlorinated
hydrocarbons
Mosquito control
Dietary intake, residues in
Toxaph-:ne, stiobane in,
spraying of cows
Cod livsr oil, analysis
DDT in olive oil, effects
DDT in, effects
Fats, effect on DDT toxicity
Sesame, use in cancer research
Application form (OS) oil
solution
Phosphamidon, colorless oil
OLIGURIA
Poisoning, effects, chlorinated
hydrocarbons
OLIVE
Chlorinated hydrocarbons, uses
Scale insect
DDT, in olive oil, effects
ORGANOMERCURIAL
Poisoning by
Economic poisons, chemical bums
Compounds, testing for
teratogenicity
OSPREY
Population declines in
OVA
Residues of pesticides in
salmon
45
62
83
•
90
127
136
140
257
297
298
431
543
645
653
373
84
216
297
442
443
664
211
129
167
-------
SUBJECT INDEX
OVARIECTOM1ZED
pjp'-DDT, nonestrogenic activity
OVERDOSAGE
Spraying
Application of water soluble
materials
Toxaphene, effect on lake
OVEREXPOSURE
Limits of pesticides in blood
to prevent
Limits of pesticides in
blood to prevent
Abnormalities in EEC,
dienc group
Acute toxicity
Personal indicators of
OVULATION
Effects of insecticide on birds
Testing in animals
OWLS
Effect of pesticides in
OXIDASES
Microsomal enzymes
MDP compounds, effect on
Effect on MDP compounds
Metabolism of MDP compounds by 554
Metabolism of MDP compounds by 559
Effect of chemicals on
OXIDATION
Removal of 2,4-D from water
Nirrophenols, effect on
metabolism
Ethylene thiourea, product of
Nabam
Drag metabolizing enzymes,
effect of chemicals on
437
107
198
213
35
234
349
382
446
211
661
516
541
548
554
559
560
123'
433
492
517
Of MDP compounds
Of MDP compounds
Reactions
Reactions of chemicals
Oxidative phosphorylation.
inhibitor) of
OXIMES
Tcmik, effect in human
Carbamoyl oximes, effects
Antidotes in animals, humans
Antidotes
OYSTERS
Polystream, use to control
snails in oyster beds
Cumulation of chlorinated
hydrocarbons
Pesticides in
Chlorinittd hydrocarbons in
Pesticides in
Pesticides in, use as
indicators
• Pesticides in, use as monitors
PACKAGING
Need improvements in
Need for more suitable
materials used in
Materials
Need for more suitable
materials used in
Materials, prevention of
accidents
Materials
Materials, accidents
Materials, design, prevention
of accidents •
548
549
554
555
640
362
367
426
453
72
118
121
129
171
185
208
18
24
77
103
159
192
193
356
168
-------
Materials, use of Dowcide-7 on
PAIN
DDT, effect on sensation of
2,4-D; epigastric effects
Oiganophosphates, effects
Organophosphates, eye
contamination, effects
inorganic a-ienicals, acute
effects
Yellow phosphorus ingestion,
effects
Anticholincstcrascs. effects
Economic poisons, effects
PAINT
Incorporation of pesticide^ into
Use of pesticides in
Dermatitis from mixture of
paint cleaner and
pcntachlorophcnol
PALATE
Carbaryl. case of cleft palate
Production of cleft pilate
PAISY
Mercurials, infantile
cerebral palsy
Fish and shellfish contaminated
with methybnercury
PANCREAS
Carcinomas of, pesticide
concentrations in, humans
Cancer of
PANTS
Epidemics of poisonings,
mevinphos
Pesticide spilled on
PAPILLOMA
Gastric papillomas, incidence of
SUBJECT
475
297
350
360
361
362
371
411
449
146
197
364
664
665
675
675
495
497
310
tot
383
486
INDEX
PARALYSIS
Motor, chronic arsenical
poisoning
Organophosphates, effects
TEPP, effects
Organophosphates, chronic
* exposure, FAA. workers
Organophosphates. effects
Orpine-phosphates, triorthocresyl
phosphates, effects
Oxures, a.itidotcs
Zoxazolai-iinc, effects of
prpercnyl butoxide on
PARASYMPATHETIC
Organophosphonis compounds.
stimulation of
para-sympathetic nervous
system
Organic phosphate pesticides.
effects OR parasyrnpathctic
nervous system
PARENTERAL
LD-50 studies
Administration, enzyme
induction
Administration, induction of
dominant lethal mutations
Administration, TEPA, METCPA,
effects, mice
Administration, testing for
teratrgenicity
PARESTHESIA
Acute DOT poisoning, effects
Occupational exposure.
organophosphorus
insecticides, effects
PAROTID
lietak. concentration in
saliva
r-UlSNlP
Linuron, uses
363
369
406
414
416
424
453
546
369
425
402
519
596
598
660
359
414
448
650
169
-------
SUBJECT INDEX
PEACH
Paradichlorobenzene. i-scs
PEANUT
Residues of pesticides in
Bromide residues in hay
Fumigants containing bromine
Effects of fats on DDT toxicity
Ethylmercury chloride, uses
Naptalam, uses
PEAR
Biological control of
prickly pear cactus
Spraying of dieldrin, orchards
Exposure of humans
PEAS
Lindane, uses
PELICAN
Toxaphene, mortalities in
fish-eating birds
PEPTIC
Ulcer, pesticide exposure,
population study, exposure to
aldiin, dieldrin
PERCEPTION
Organophosphonis compounds,
effect on depth perception
Organophosphonis compounds,
effect on light, depth
perception
Pesticides, effects on depth
perception
Occupational exposure, effects
TEPP, effects on depth
perception
PERCUTANEOUS
Absorption, route of entry
Absorption
Absorption, washing of skin
tc reduce
Penetration
Penetration, parathion,
051
133
198
198
431
649
651
82
155
155
650
211
351
361
367
406
406
406
263
264
400
401
paraoxon
Effect of vehicles on
Sample skin matrix
Temperature, effect on
PERINATAL
Chlorinated hydrocarbons.
residues in human milk.
not related to perinatal
toxicity
PERITONEAL
Injection, host-mediated assay
PERMISSIBLE
Limit, mcthoxychor
Levels
Levels, enzyme induction
PERS'STENT
Residues of, in air, soil,
water
Use of, need for review
Pesticides, residues
Chemicals, provide incentives
to industry to develop
specific, less-persistent
chemicals
Chemicals, use of
Pesticides, decline in use
since 1957
Pesticides, need to replace
Need for development of
less-persistent pesticides
Pesticides, exposure to
Pesticides, salts of heavy
metals
Insecticide use patterns
DDT. use in malarial
eradication
402
403
405
432
674
594
301
495
519
9
10
12
17
19
21
23
24
35
45
48
49
170
-------
SUBJECT INDEX
Restrictions in use of,
methoxychlor usage 51
Use of, in pest control
industry 53
Use in insect contiol 54
Use of, insecticides 55
Pesticides, residue problem,
new pesticides 59
Organochlorincs, chlorinated
hydrocarbons 63
Phenoxy herbicides, soil 68
Phenylacetic acid, soil 68
Bcnzoic acid compounds, scQ 68
Phthalic acid compounds, soil 68
Substituted phenol herbicides,
soil 69
Heterocyclic nitrogen
derivatives, soil 69
Substituted ureas, soil 69
Carbamates, soil 70
Other amides, soil 70
DinitroanUinc herbicides, soil 70
Nitrite herbicides, soil 70
Plant growth regulators 73
Interest in 79
Toxicity to humans 102
Pesticides 103
Gradations of, chemicals 104
Of pesticides in air 105
Of pesticides in atmosphere.
effect of formulation, size 108
Of pesticides in air 114
Of pesticides in air US
Pesticides in marine environment 121
Water quality 122
Endrin, in water, fish, plants 125
Metabolism of pesticides by
plants 133
Chlorinated hydrocarbons 136
Guthion, on fruit 142
Pesticide type and formulation 143
Use of DDVP with Diazinon,
chlordane 151
Commercial pest control 152
Pesticides, DDT, occupational
exposure, residues in adipose
tissue 153
Development of nonpersistent
pesticides 161
Chlorinated hydrocarbons, use
reduced over next 2 yeurs 180
Effects on biological systems 187
Tree preservation, use of DDT 196
2.4-D. in soil 203
Herbicides 204
Plant growth regulators 205
Arsenic acid, sodium arsenitc 205
Pesticides, effect on
nontarget organisms 206
Insecticides, effect on
nontargct fish 210
DDT.cflecUinfish 210
Chlorinated hydrocarbons 211
Chlorinated hydrocarbons,
effects 212
Toxaphenc, effects on
aquatic fauna 213
Pesticides, exposure to 234
New pesticides 238
Action to improve protection
of public health 239
Discourage home use of
persistent pesticides 239
171
-------
SUBJECT INL'EX
Of pesticides
Role of dietary sources of
pesticides
Exposure to pesticides
Thallotoxicosis, neurological
damage
Effects, pesticide exposure
Pesticides, DDT
Pesticides, interactions,
tissue storage
Pesticides, needed information
on enzyme induction
Pesticides, need for
mutagcnicity testing
Fumigants. effects on humans
PHARYNGITIS
Paraquat ingcstion
PHEASANT
DDT, egg shell thinning in
ducks, not pheasants
DDT. egg shell thinning in
ducks, not pheasants
Deaths in, from seed dressings
containing pesticides
PHEROMONES
Potential uses of
Advantages, disadvantages of
Sex phcromones. uses
Developmental phcromones
PHOTOLYSIS
Exposure of pest:cul« to air
PHOTOSYNTHESIS
Pesticides, effect on
DDT, effect on marine algal
Pesticides, effect on
Solar energy, use in
248 DDT, effects on
Structure-activity-relations,
207
326
357
363
415
472
525
530
603
611
373
25
179
200
61
81
219
219
114
25
121
179
186
inhibition of
PHYTC'rt-ANKTON
Production of oxygen by
DDT, effects on
Pioduction of oxygen by
Ncodcd observations on
Effects of pesticides on
Need for investigation of
effects of pesticides on
PHYTOTOXIC
Fungicides, problems of
Cereals
Aldrin, dieldrin as seed
dressings without
phytotoxicity
Volatile liquids, less
•* phytotoxic
Residues in soil, effects
PIGEON
Avicidcs, use to control
\vitrol, use to control
Consideration of pest probl-m
PICS
Guinea, isco to collect fleas
in buildings
Oui.-vM, allergic sensitization
Guinea, metabolism of Guthfon
DDT storage in, sex difference*
Guinea, ethyl fenthion toxicfty
in, sex differences
Guinea, malcic hydrazide.
mutagenicity testing
PINEAPPLE
Auxins, uses
Monuron, uses
604
28
121
182
205
207
207
66
85
85
198
214
73
7?
214
83
399
426
428
429
642
74
651
172
-------
SUBJECT INDEX
PISC1C1DE
Use of
PLACENTAL
Transfer of dieldrin and
incidence of stillbirths,
cows
DDT, DDE, passage of through
PLAGUE
Use of BHC, dieldrin
Materials used for control of
DDT, control of vectors, of
PLASMA
Cholinesterase levels
Parathion exposure
DDT, effect on bilirubin levels •
Dieldrin exposure, humans
DDT levels, humans
Dieldrin exposure, humans
Baygon, effect on cholinesterase
DDT levels, rats
DDT in. human
Aliesterascs
AUesterascs, needed studies
Glucocorticosteroid level,
effect on
PLASTIC
Polychloiinated biphenyls,
use in
Storage of samples in plastic
containers, source of error
in analysis
PLUMS
Fate of malathion residues on
PNEUMONIA
Intoxicatioi by economic
poisons, effects
POISONINGS
73 Need for regulations, collection
and disposal of pesticides,
665
674
90
214
296
260
296
300
301
329
349
361
431
449
510
S13
533
257
257
141
449
containers
Dieldrin, endrin
Poisonous, Compound 1080
(sodium monofluorcacetate)
New methods of application
Stomach poisons
Contact poisons
Fumigant poisons
Pyrcthrin, allcthrin, nerve
poison, insects
Organophosphatcs, exposure to
Contact, stomach, carbamatcs
Nematocides
Strychnine baits
Invertebrates, molluscicides
Thallium sulfate
Attractants, incorporation
into poison baits
Toxicity scheme, need for
education of consumers
Parathion, humans
TEPP, humans, livestock
ODD, fish, birds
Household use of pesticides
Occupational exposure
Parathion
Parathion
Accidents
Accidents
Nerve poison, DDT. DDE, ODD
18
34
45
60
61
61
61
63
64
65
70
72
72
73
75
77
81
83
127
145
153
155
156
157
158
189
173
-------
Arsenic
Birds, DDT
Avicides
Organochlorine
Acute, organophosphates in
bulk food, water sources
Pesticide protection teams,
investigation, reporting
Occupational exposure
Acute
Acute, animal, vs human
In homes
Experimental oral exposure
to DDT, humans
Acute, epidemiology of
Humans
Occupational
Children, adults
Epidemics of, by pesticides
Epidemics of, by pesticides
Pesticides, humans
Acute
Occupational, acute,
organophosphates
Carbamate
Organophosphates
Clinical case reports
DDT, acute, effects on the
nervous system
Organophosphates, symptoms
Baygon, humans
SUBJECT
206
211
214
233
234
241
250
251
259
263
297
305
306
307
308
310
311
314
319
347
348
356
358
359
360
361
INDEX
Organic mercurials
Inorganic arsenical*
Thallium
Thallium sulfate, chronic,
effects
Effect* on the eye
Diazinon, effects
Organophosphorus compounds
Paraquat, effects
Yellow phosphorus ingcstion
Chlorinated hydrocarbons, humans
Chlorinated hydrocarbons, humans
Organophosphatcs, humans
Systemic
Organophosphatcs, neurologic
abnormalities
Acute, humans
Behavioral effects of
pesticides
Acute, chronic
Chlorinated insecticides, acute.
effect on nervous system
Organorihosphatc
Organophosphale
Occupational exposure
Organophosphate
Phosdrin and/or Parathkm
Acute, organophosphates,
behavioral changes
Fatal, human, animal
experiments
DDT. animals, effects
Norbormidc, effect in rats
362
362
363
365
366
367
369
370
371
372
373
373
383
389
434
406
407
408
412
414
415
416
417
418
424
425
426
174
-------
SUBJECT INDEX
Parathion. humans
Organophosphates, sex
differences
Diseases, effect on
DDT, humans
428
429
430
430
Of estuaries
Of sir, water
Environmental
Soil
Nutrition, effect on 431
Organophosphates, effect of
temperature on 433
Chlorinated hydrocarbons, rats 435
Chlorinated hydrocarbons in rrulk 437
Humans, reported by Poison
Control Centers 442
Economic poisons, effects 443
Personal protective equipment 444
Airplane pilots 445
Characteristics of 446
Diagnosis of 447
Parathion, use of
p-nitrophenol as indicator
in treatment of 448
Cholinesterasc inhibitors 449
Pesticides, symptoms 449
Diagnosis, hypersensitivity 449
Atropine. use in 450
Chemicals, use to treat 451
Atropine, UK in 452
Organophosphorus compounds 453
Useofatropine,
tetraethylammonium chloride 454
Atropine, use in 534
POLLUTION
Early warning system, use of 31
Air, interest in 79
Of ground waters H6
Of water by pesticides 118
Of environment
Environmental
In aquatic environment
Hazard, pesticides
Environmental
Environmental
Air pollutants, interaction
with pesticides
Air pollutants, interaction
with piperonyl butoxide
Environmental pollutants,
effect on piperonyl butoxide
Water pollutants, tested for
mutagenicity, mice
POLYMORPHONUCLEAR
Lindane, effects ,
POLYNEURITIS
Mipafox, production of
Organophosphates occupational
exposure, effects
Aldrin, dieldrin, suspected
human cases of
PONDS
DDT, applied to, concentration
in water
Contamination by endrin
Parathion in
Transport of chemicals in
PORPKYRIA
Occupational exposure to
phenoxy herbicides (2.4-D;
2.4,5-T). effects
121
192
193
195
196
197
202
215
220
409
525
541
546
598
350
413
414
417
120
120
144
187
350
175
-------
SUBJECT INDEX
Hexachlorobenzcne,
contamination of grain,
effects in humans
Hexachlorobenzcne,
contamination of grain,
effects on humans
Hexachlorophenc-induced,
rats, photosensitivity in
Structurc-activity-rclations
Mode of action; inhibitor
of porphy rin
POSTEMERGENCE
Heterocyclic nitrogen
derivatives
Postemcrgence activity
Herbicide, paraquat, diquat
Herbicides; 2,4-D; 2.4,5-T
POTABLE
Water supply
Standards, limits
POTATO
Paris Green, use against beetle
Organochlorincs, uses
Growth rctardants, uses
Total insecticide usage,
chlorinated hydrocarbon usage
Crops, including sweet potatoes
Chlorinated hydrocarbon residues
DDT residues in
Aldrin, trandocation in
Endrin, occupational exposure
Resistant plants
Sodium anenitc, use as
potato vine killer
Linurcu, use on
hhptalam, use on
Maletc hydrazide, use on
POTENT1ATOR
364
372
433
604
604
69
69
205
610
121
121
45
55
74
84
87
136
141
144
155
162
205
650
651
651
Drugs, potentiate poisoning
Of malathion toxicity
Of malathion toxicity
POULTRY
Mongoose, effect on
Chlorinated hydrocarbons.
dietary residues
Raisers, use of pesticides
Seed treatment, hazards to
Mongoose, effect on
Pesticides, residues in
Pesticides, residues in
Caibaryl, uses
PREEMERGENCE
Phthalic acid herbicides
Phthalamic acid compounds
Substituted phenol herbicides
Heterocyclic nitrogen
derivative herbicides
Substituted ureas
Carbamates
Other amides
Dinitroanilinc herbicides
Nitrite herbicides
Herbicides
Chlorpropham, herbicide
Naptalam, herbicide
PREGNANCY
Losses, need for increased
Federal support of research
Information needed.
interpretation
Dominant lethal assay
Methodologies for
teratogenicity testing
418
512
513
82
136
1%
200
216
385
537
646
68
68
69
69
69
69
70
70
70
610
646
651
16
260
597
658
176
-------
SUBJECT 1NJ >EX
Thalidomidc, effects in humans
Testing of compounds, animals
Animals during, handling of
PCNB administration, mice
Methods of testing
Chlorinated hydrocarbons in.
humans
Mercurials, consumption of fish '
by Japanese, effects in
PREHARVEST
Auxins
Uses
Arscric acid, use as dcssicant
PREIMPLANTATION
Dominant lethal mutation
measurements
Losses
ISFNATAL
Teratology
PRETREATMENT
Organochlorincs
DDT
Organophosphatcs
Of cells
PROTHROMBIN
Pesticide usage, effects on
Anticoagulant rodenticides,
effects
PROTOZOA
History of pesticides
Alternate control techniques
Insect pathogens
Pathogens
PSYCHIATRIC
Symptoms. DDT ingestion
Drue literature
659
660
661
666
667
674
675
74
74
205
597
598
657
55
120
518
593
351
451
44
60
163
216
391
408
Symptoms, organophosphatcs
DFP exposure, humans
Oiganophosphate poisoning,
effects
PSYCHOGENIC
Odor
Odor, pesticides
PSYCHOLOGIC
Organophosphate, effects
Evaluations in children,
poisoning cases
PSYCIfONEUROSIS
Of non-pesticide origin
PSYCHOSIS
Miscellaneous pesticides,
ingestion, effects
Behavioral changes
Of non-pesticide origin
Reactivation by DFP
Pesticides, not established
as causing
PSYCHOTIC
Symptoms, pesticide exposure
Symptoms, reactivated by DFP
Organophosphate poisonings.
effects
PULSE
Chlorpromazinc, effect on
PUPAE
Insecticides, control of
Sterilization of
PUPS
Group size
PYREXIA
Organophosphates, exposure
of pilots to, effects
PYROLYSIS
Disposal methods
QUAIL
DDT, no production of egg
shell thinning in
413
413
416
415
419
411
417
418
371
413
418
418
419
413
413
415
418
53
83
484
414
159
25
177
-------
SUBJECT INDEX
DDT, no production of egg shell
thinning in
Heptachlor, effect on quail
population
Estrogenic activity of
oj> '-DDT in
RABBITS
Botanical rodenticides,
effect on
Fate of cyclodienes in
ADcrgic sensitization
Parathion, paraoxon dermal
absorption in
DDT poisoning in. effect of
liver damage
Metabolism of MDP compounds
Rperonal excretion in
Teratogenicity testing, use of
lower mammalian species
Cap tan, teratogenic in
RACCOON
Chemical control measures for
RADISHES
Aldrin, trandocation of
from soil
RAGWEED
Pest problem
RAIN
Pesticides, precipitation from
Pesticides in air. decrease
levels after
Pesticides in
Endrin in runoff water
Effect on Guthkm residues
Leaching of pesticides from
soU by
Diddrin in runoff water
179
211
665
72
268
399
402
430
547
S47
659
664
71
58
"4
H*
125
142
144
Resistant crops, effects of
rainfall on 161
Effect on granule formulations
of pesticides 200
RATS
Pesticides before 1945 44
Red squill, use 44
Red squill, use. supply 45
Inorganic rodenticides 71
Botanical rodenticides 72
Red squill, use 72
Miscellaneous rodenticides 72
ANTU, use 72
Raticate, use 72
Mongoose, use to control 82
Pests, controlled by pest
control operators 150
Endrin contaminated bread,
effect on 158
o,p ;-DDT, effect in 213
Mongoose, use to control 216
DDT in 264
HEOD in 265
HEOD in 266
HEOD in 267
HEOD in 268
DDT in 269
HEOD in. model 272
DDT storage in, vs concentration
in diet 275
HEOD in. vs daily intake 279
DDT in, concentration in diet 281
HEOD in, concentration in diet 284
HEOD in bodyfatvs blood 285
DDT in. during post-exposure 287
178
-------
SUBJECT INDEX
HEOD in adipose, during
post-exposure
HEOD in blood, liver, during
post-exposure
Yellow phosphorus, use
DDT, effect on locomotion
Carbaryl, Baygon, effect on
self-protective responses
Parathion. effects in
DMSO, effect on spontaneous
motor activity
Metabolism of DDT to DDE
Nofbofinide, use
EPN. ethyl fenthion, toxicity
Malathion, DDT, dieldrin.
toxicity
Cholinesterase insecticides,
toxicity
DDT, acute oral toxicity
Hormones, effect on
storage of DDT, DDE
Ethyl ferthion, toxicity.
sex differences
Pesticides, LD-50
DDT, tricliinosis interaction
Carbon tetrachloride damaged
fivers, effect on
methoxychlor toxicity
DDT toxicity, effect of fat
indict
DDT storage, excretion, effect
of starvation
Dieldrin. effect of dietary
protein on toxicity
Nutrition, effect on dieldrin
toxicity
Malathion, effect of
temperature on toxicity
DDT, Warfarin, Azinphosntethyl,
effect of temperature
oo toxicity
292
293
371
409
410
411
417
424
426
427
427
427
428
428
429
429
429
430
431
431
432
432
432
DDT, temperature, effect on
physical performance 433
DNOC. dinitro-o-phcnol,
toxicity, effect of
temperature 433
Hexachlorobenzcne-induced
porphyria, photosensitivity 433
DDT, liver changes 434
Diekuin, liver changes 435
Chlo'inatcd hydrocarbons, liver
ciianges 435
Enzyme induction, phenobarbital 436
Technical DDT; p.p '-DDT;
o,p '-DDT; methoxychlor,
effects, estrogenic
Chlorprophara, tumorigenicity
testing
Pyrethrin, tumorigcnicity
testing
Endosulfan, Clyodin,
methoxychlor, tumorigcnicity
Metabolism of chemicals
Mali thion, toxicity
Phenobarbital prctreatment,
cfTict on toxicity
DDT, toxaphene, intake,
enzyme induction
Enzyme induction measurements
in progress
Aldrin, Chlordanc, Lindane,
effect on subsequent
Parathion poisoning
Tween 20. effect on Beta BHC
levels
Storage interactions
Aldrin, Dieldrin, interactions
DDT, effect of starvation
437
469
474
475
513
514
518
519
520
524
526
527
528
529
432 Gamma BHC. effect of fat in diet 530
179
-------
SUBJECT INDEX
Low protein diet, efccts
Temperature, effects
Radiation, effects
Pipcronyl butoxide, effect on
MDP compounds
Pipcronyl butoxide toxkity
Safrole, effects
DDT, pyrcthrum, pipeionyl
butoxide, liver effects
Piperonyl butoxide, effect
on hexobarbital sleeping time
Metabolism of MDP compounds
Mode of action of MDP
compounds
Host-mediated assay
Dominant lethal test
Teratogenicity testing, use of
tower mammalian species
Organochlorines, embryotoxicity
Thiram, teratogenicity testing
2,4,5-T; effects
RECTUM
Cold water, use in treatment
of poisonings
Pesticide concentrations.
carcinoma of
RENAL
Needed development of methods
for detection of effects
of pesticides
Organophosphatcs, effects
Paraquat poisoning, effects
Occupational exposure, effects
Prcemployrnent examinations
VCNB. renal agenesis
532
533
533
541
542
543
544
546
547
554
594
597
659
664
665
666
451
495
244
347
370
388
443
666
REPELLANT
Avicidcs. anthraquinone,
tliiram
Insect
Development of
Use against mice
Uses
Application form (R)
REPOPULATE
Soil organisms
REPRODUCE
Inhibition of insect reproduction
Cultural or environmental
control
Pesticides, effects in birds
DDT, effect in lake trout
Pesticides, effects in fish
Birds, effects
Dicldrin, DDT. effects in birds
Dicldrin, effects in deer
Chlorinated hydrocarbons.
effects
Effect of pesticides on
Piperonyl butoxide. effects
Somatic mutation methods
Agents which interfere with
ability, mutagenic
Methodologies for teratogenicity
testing
Miscellaneous reproductive
effects
Chlorinated hydrocarbons.
effects
73
75
83
200
215
645
205
83
164
179
209
210
211
212
213
373
437
542
578
602
658
665
674
180
-------
SUBJECT INDEX
RESIDUES
Of persistent pesticide* in
environment
In food, water, restriction of
exposure
Consideration of, development
11
of standards
DDT, in fish, environment
Pesticides, Delaney clause
Organophosphatcs
Dieldrin
Persistent pesticides,
development of new pesticides
Organochlorines
Organophosphatcs
Effects on enzyme systems
Spraying of houses with
gamma BHC. use in Chagas
diwa*^
2,4-D in water, effects
Binding to soil particles
2,4-D in water
In water, use of pesticides
In estuaries, levels
In soil, from soil to plants
In seed crops, soil content,
fat content of seeds
Effect of plant
characteristics on
Chlorinated hydrocarbons in diet
Herbicides
Inorganic
Chlorinated hydrocarbons
Toxaphene, in cattle
12
13
14
35
52
59
63
64
81
91
117
118
126
128
129
132
133
134
135
136
137
138
139
Spraying, cattle 140
Mala'.hion in foods 141
Cuthion 142
Alton, soil 143
HeptachJor, soil 144
In soil 145
Resistant crops 161
Insect parasites and predators 162
In food, feed 170
Pesticides in soil 171
Measurement in foods 173
Methods for extracting 174
DDT in food web 188
Bromide, fumigants 198
Bods, effects on 211
Ovmical in soil, phytotoxicity 214
Orpnophosphates 234
Tolerances, registration.
recommended practices 238
>n foods, cpidcmiological
complexities 250
General population studies 255
Ingestion, on foods 263
Of HEOD in tissues 269
Organochlorincs in human
population 273
Human, pesticides 319
Polychlorinatcd biphcnyls 320
Adipose, blood. DDT, DDE 321
DDT, humans, sex differences 322
181
-------
SUBJECT INDFX
DDT. humans, age differences
DDT, metabolites, effect
of drugs on
DDT, place variable
DDT, time variable
DDT, discussion
DDT, dietary source
DDE, patients
Secular changes
DDT, pathologies
Adipose, humans
Adipose, humans
Adipose, humans
Adipose, humans
DDT, adipose, effect of age
Human, DDT, Dieldiin
Human, DDT, dieldrin
Human, p.p'-DDE; dieldrin; DDT 340
Human; p.p'-DDE; dieldrin; DDT 341
Mortality and morbidity
studies
Organophosphates
DDT. humans
Chlorinated hydrocarbons,
effects, birds
Chlorinated hydrocarbons,
humans
Food additive
Foods, reduction of. DDT, DDD
in food production
Pesticides in foods, testing for
tumorigenicity
Combined, pesticides
323
323
324
325
325
326
327
328
329
331
332
333
334
335
338
339
340
341
344
347
357
437
447
464
472
478
512
Persistent pesticides
Interactions, pesticides.
detergents
DDT, physiological interactions
Organochlorines
Tissue storage of pesticides
l-'actors determining storage
HOT, DDE, environmental
exposure
Organochlorines
DDT, human placentas
RESISTANCE
To pesticides, factors
influencing changing patterns
Hydrogen cyanide, insecticide
To DDT
To DDT
Rootworms, Organochlorines
Cf pests, chlordane
Of pests
Development of plants
To insecticides, Organochlorines
Need for development of crops
Soldier fly (Australia),
controlled by dieldrin
Frequency of application, effects
Mosquito control, use of
chemicals
Diazinon. use for roaches
Crops
Plants
Bacteria spores, resistant
to conditions
525
526
529
530
536
537
538
539
674
22
45
46
50
52
S3
59
60
63
81
89
108
127
151
161
162
163
182
-------
Planting of resistant strains
To diseases, pesticides, effect
on fish
Hosi, to pests
Guinea pig, Guthion
Ethyl fenthion, rats
To DDT, fish
Syncrgists
Chinese hamster cells
RESPIRATORY
Fumigants, entrance in body
Exposure, parathion
Occupational exposure
Occupational exposure,
parathion
Occupational exposure
Pesticides, effects in fish
Exposure, parathion. human*
Exposure, DDT, humans
DDT exposure, humans
Organophosphates, effects
2,4-D; effects
Diseases, pesticide exposure
Organophosphates, effects
Pesticides, effect on
I
Chlorinated phenols.
effect on
Occupational exposure
Signs and symptoms
Symptoms, occupational
exposure
Exposure, parathion
Failure, acute poisoning
SUBJECT INDEX
167
210
217
426
429
431
542
588
62
112
153
155
itjtj
156
210
£1U
296
296
298
347
350
352
361
369
17ft
JIV
383
389
394
402
416
Satin toxicity, effect of
tempera tine
Condition, pesticide exposure
DDT exposure, humans
Organophosphates, effects
RESTAURANT
Use of lindane, evaporation
materials in
Discontinuance of needed
Use of lindane in.
discontinuation of
Analysis of meals, for DDT
conten:
DDT, DDE, in meals
RETROBULBAR
Thallotoxicosis, production
of neuritis
Chlorinated phenols, neuritis
from
RHINORRHEA
Organophosphorus compounds.
effects of eye contamination
Organophorus compounds, effects
of eye contamination
RHIZOBIUM
Linuron, mutagcnicity
testing in
RHIZOPUS
DCNA. uses
RICE
Endrin, use of insecticides
for posts
Insecticide usage
Rfce crops, use of
insecticides on
Fate of aldrin in
Specific-locus method in pollen
432
443
445
534
23
23
102
114
385
363
367
361
367
642
647
52
84
85
124
578
183
-------
SUBJECT INDEX
RIVER
DDT, DDE in
DDT contamination of
Ptscicides, uses
Blindness, DDT in
Pesticide pollution of
Aldrin, dicldiin in
Pesticides in
Pesticides in
Pesticides in
Pesticides, effects on fish in
RNA
Enzymes in stratum corneum.
hydrolysis of
Acrylonitrilc, assay system
ROACHES
In households
i
Pests, commercial pest control
Pests, commercial pest control
Chemicals for control
Baits for, need for protection
of household members
ROBIN
Mortality of
Mortality of
RODENTS
Pests
Inorganic rodentitides for
Botanical rodcnticides for
Kepone pellets, use to control
Pesticides, application to
•control
Thaliiuir., as*
Pests
9
13
. 73
91
118
125
128
129
171
210
401
639
147
150
151
309
356
210
211
71
71
72
151
197
309
381
Carcinogcnesis in
DDT, effects in
DDT, effects in
Recommended observation
period in
Enzyme induction in
Dominant lethal test
RODENTICIDES
Compound 1080
And mammalian biocidcs
Botanical
Anticoagulant
Flue ride
Miscellaneous
Need for more toxic
And other mammal biorides
U.S. pesticide production.
annual
Thallium suUatc, uw
Poisoning cases, humans
Anticoagulant, therapy for
poisonings
Application form (Ro)
Endrin, use
RUBBER
Protective clothing, gloves
Protective clothing, gloves
RUST
Fungi
Resistant plants
RYE
Losses due to insects
SABADILLA
Use as louse powders
Botanical insecticides
395
424
425
468
528
596
45
71
72
72
72
72
151
214
315
363
442
451
645
648
77
444
81
162
86
44
62
184
-------
SUBJECT INDEX
SALIVA
Organophosphatcs, effect on
Mercury in.
Pesticides, effect on
SALMON
DDT in
Pestic'-des in
Pesticides in
Pesticides in, effect on food
Pes»:ades in
SALMONELLA
Reverse mutation system in
Host-mediated assay
SARCOMA
Cocarcinogenic activity of
sesame oil in production of
SCALP
Chlorinated acid derivatives,
effects
SCHISTOSOMIASIS
PCP, use to control carriers of
SCHIZOPHRENICS
Improvement by injection of
acetylchotinc
Organophosphates, exposure,
FAA workers
Improvement of injection by
acctylcholine
Preexisting, pesticide exposure
SCREWWORM
Eradication program
SEAFOOD
Estuaries, producfon of
SEIZURE
Organophosphates. halogenatcd
hydrocarbons, patterns in EEC
SERUM
DDT, use to decrease bilirubin
levels, humans
DDT. DDE in. humans
327
360
448
449
118
129
220
357
572
594
543
365
652
413
414
s'18
419
164
220
443
Amino acids in, enzyme
induction
Occupational exposure, albumin
Occupational exposure, amino
acids
Human Monitoring Survey
Teratogenicity testing.
metabolitrs
SEWAGE
DDT, metabolites in
Pesticide;!, treatment
SCOT
Oral exposure to dicldrin.
humans
Occupational exposure to
pesticides
SHEEP
C'asshopper control
Spraying of, with Sevin,
residue study
Storage of dieldrin in
Use of mammalian species for
te-Jng
SHELLFISH
Accumulation of pesticides
Pesticides in
Pesticides in
Marine invertebrates
Consumption of, contamination by
mcthylmeuury, humans, effects
SHOCK
3igns and symptoms of
intoxication
Ingestion of yellow phosphorus.
effects
348
351
388
496
660
9
201
301
351
91
139
265
659
118
120
129
208
675
360
371
300
Experimental carbamatc
pesticide, effect on rats,
conditioned avoidance
410
185
-------
SUBJECT INDEX
SHRIMP
Marine invertebrates 208
Susceptible to chemicals in
water 208
Heptachlor, cndrin, lindane.
effect on 209
Developmental pheromones 219
Danger to non-target
organisms 219
SHRUB
Inorganic insectici Jcs 62
Lead arsenale, us? on, to
control chewing insects 62
Herbicides, effects on nontai;rct 203
SINUSITIS
Correlation studies,
occupational exposure,
effects 148
Association with pesticide
usage 3S2
Correlation studies, effects of
household exposure to
pesticides and effects 370
SKELETAL
Carbaryl. skeletal
malalignmcnt in mice 661
SKIN
Penetration of, organochlorines 33
Penetration of, or^anophosphatcs 34
Absorption through, repellents 75
Penetration, para t Won 81
Potential exposure hazards 112
Penetration, persistent
pesticides 135
Contact, lindane 149
Occupational exposure 152
Penetration, paratnion 155
Absorption, accidents 158
Contact. Paraquat, Dtquat 205
Routes of entry of pesticides 263
Diseases, occupational exposure 307
Serialization reactions,
dicne group 349
Hypcrpigmentatioii, freiriUty,
phenoxy herbicides 350
Topical effects, organophosp^iates 360
Chronic arsenical poisoning,
effects 363
Effects on. pesticides 363
Gentian Violet, effects on 364
Nitrogen compounds, herbicides,
effects on 365
OccupationaUy related
conditions 366
Paraquat, effects on 370
Absorption, poisoning 383
Adsorption, annual intake
DDT plus DDE 384
Exposure, decontamination of 400
Cuuneous metabolism 401
LD-50 402
Parathion exposuic 403
Vehicles, penetration 404
MTtrix 405
Paraquat, diquat effects 405
Orgauophotphate. effect on 411
Parathion, metabolism in
humans, effect of pathology 430
Condition, pesticides 443
2,4-D; 2,4,5-T effects on 4SC
Atropinc effects 43*
Absorption, routes of exposure
of pesticides, need for
tciatogenicity testing 657
186
-------
SUBJECT INDEX
SKUNK
Rodcnticides and mammalian
bioctdes 71
SLEEP
SfcepLig sickness, i x of
pesticides in ?1
Patterns, organophosptialc
exposure 415
Patterns 416
HexobarbiUl steeping time,
DMSO effects 417
Loss, effect r*i Continuous
Performance Test 418
fbolinestersse inhibitors.
effects 447
Hexobarbital steeping time.
effects of orgiqophosphaies on 518
Hexobarbital steeping time,
piperonyl butoxide on 546
SLUGS
Matacfl, use in controlling 72
Meuidehyde. component of bait* 73
SMOKE
Sources of pesticides,
effluents 242
Environmental source* of
pesticides 242
Precautions during pesticide
application 444
SNAIL
MataciLuses 72
Bayhiscide.uses 72
Polystream, utw 72
MetaMehyde.use* 73
Use of pesticide* for,
precautions 103
DOT in 120
Pesticides to cofi'rol,
precautions 125
fCP.utes 652
SOAP
Wash for decontamination
ofskin 4oo
Use. to remove pesticide skin
contamination 450
SOIL
Contamination 22
Pesticides in, concentration
in organisms 25
Persistence in 45
Insects, methoxychlor use 51
Heptachtor, use 52
Chlordane, use 53
New methods of application 60
Organochtorines 63
Dithiocarbamate fungicides 66
Slerilants 67
Carboxylic aromatic 68
Phenoxy herbicides 68
Benzoic acid herbicide?. 68
Phthalic acid compounds 68
Phthalamic acid compounds 68
Aliphatic acid herbicides 69
Substituted phenol herbicides 69
Heterocyclic nitrogen
derivative herbicides 69
Substituted ureas 69
Carbamates 69
Amides 70
Dinitroaniline herbicides 70
Nitrite herbicides 70
Cytnate nematocides 71
Organic phosphate nematocides 71
Halogenated hydrocarbon
nematocides 71
Plant growth regulators V4
Cotton crop*, cyctedienes. a*e 84
Cereal crops, cyclodienes, use 86
v
Potato crops, cydodtenej, use 87
18?
-------
Sugar beet oops, cyclodiene, use
Sugarcane crops, aldrin,
heptachlor use
Contamination
Dieldrinin
Particles, pesticide adherence to
Pesticides in, to plants
Residues, heptachlor, heptachlor
epoxide, aldrin, dieldrin
DOT in, residues in potatoes
Contamination
Moisture, temperature
Leaching of pesticides from
Condition, effect on crop
resistance
Pesticide levels in
Pesticides in
Storage of pesticides
Pollution
Application of pesticides to
Granules, pellets in
Pesticides in
2,4-D; breakdown in
2,4.5-T; MCPA, breakdown in
2,4-D; effect on organisms
Fumigants
Residue, phytotoxicity
Spores, milky disease
bacterium, viability
Picpatation
Degradation in
Pertiddeiin
SUBJECT INDEX
88
89
101
116
118
132
133
141
143
144
144
161
170
171
175
195
198
199
201
203
203
204
205
214
216
218
249
328
DCNA,uses
Dieldrin, uses
Formaldehyde, uses
Panthion, uses
SONIC
Physical pest control methods
Pest control
SORGHUM
Losses due to insects
Cereals
Linuron. use
SOY
Oil seeds, use of chlorinated
hydrocarbons
Caibaryl, use on
Tentative guidelines, crop
Residues of pesticides in
Animal feed
Linuron, use on
Naptalam. use on
SPARROW
Hawk, population decline
Hawk, exposure to DDT,
dieldrin
Hawk, population reduction
from DDT
SPERM
Specific locus test
Captan. effects
DDT, effects
Malcic hydrazide
SPIDER
Mites, affected by fertilizers
647
648
649
652
165
167
86
95
650
90
104
124
133
138
650
651
211
212
665
596
639
640
642
218
188
-------
SUBJECT INDEX
SPINAL
Chlorinated hydrocarbons.
action in, found in
Diazinon poisoning.
pathology in spinal cord
Chlorinated hydrocarbons.
action i.i
SPLEEN
Tests, suitable for assays
HCN (hydrogen cyanide).
tested in
SPROUT
Growth retardunls, effects on
Dicldrin, testing for
mutagcnicity
Malcic hydrazidc, uses
SPRUCE
Spray application for budworms
SQUIRREL
Botanical rodcnticidcs.
strychnine use for
359
367
408
589
640
74
640
651
111
72
DDT, rats, effect of
starvation
Dicldrin, human bl-.od.
effect of starvation
STERILE
Male technique, pest control
Cultural or environmental
control
Injection of juvenile hormone.
effects
Radiation, effects
Induced sterilization
Pesticides, effects on pests
Mutations, effects
Dominant lethal tci.
Adverse genetic effects
STEROID
Effects of, on birds
Enzyme induction by
529
530
82
164
165
167
219
569
571
596
598
211
329
STAMEN
Somatic mutation methods.
detection of 577
Loss of reproductive
integrity of 578
Use of specimens to detect
chemical mutations 578
STARLINGS
Avicides, use to control 73
AviUol, use to control 73
Thallium sutfate, use to
control 73
Species rhoscn for monitoring
of nesticides 171
Chemicals, use to control 214
STARVATION
Organochlorincs. effects in
starved animals . 431
DDT poisoning in birds, effect
of starvation 431
DDT storage, excretion, in
rats, effect of starvation 431
Paraquat poisoning, use of
steroid therapy, effects of -10
Chlorinated hydrocarbons. '
alterations in steroid
metabolism 373
DDT, effect on conversion of
steroids to metabolites 437
STILLBIRTH
Placenta! transfer of dicldrin
incidence of stillbirths
in coivs 665
Incidence of stillbirths in
cows fed DDT W5
STOMACH
Poisons, definition of 61
Organochlorines, chlorinated
hydrocarbons, effect from
p. olongcd stomach action 63
Carbimates, node of action 65
-------
SUBJECT INDEX
Altftin, dieldrin exposure.
diseases, carcinoma of
the stomach
Therapy for poisoning
Pesticide concentrations, in
persons with carcinoma of
the stomach
STOOL
Safely evaluations, softening
of stools, high intake of
cyclamates
Excretion of pesticides in
STRINGBEAN
Fate of malathion residues in
SUBACUTfc
Experimental dermal exposure
to DDT
End'tin. administered to
monkeys
Need for enzyme induction
studies
EPN, malathion, feeding
studies, effects
Studies, rats
Need for enzyme induction
studies
Toxkity of MOP compounds
Induction of dominant lethal
mutations
SUBCUTANEOUS
Fat, DDT in
Administration of
dimethylnitrosmmine.
carcinogencsii study, mice
Administration, sesame o3.
cncinogeiuc, mice
Aammbaation, Frcon,
piperonyl butoxidc. mice
Host mediated assay
3S1
450
495
Administration, phcnylmcrcurk
acetate, effects in mice 664
Methods of testing,
administration 667
SUBLETHAL
Effect on nun-target specks,
need for icv^w of
pesticides 29
Effects on non-target species.
245
401
141
2%
410
510
512
513
519
542
596
264
484
543
545
594
I1CCU 1UI JCVICW Ot
pesticides
Crustacea, effects of
pesticides in
Effects of insecticides on birds
Enzyme induction, rats, mice
Radiation, rats, effects
SUGAR
Beet, crops, use of
insecticides OP.
Beets, use of cyclodienes on
Beet losses due lo insects
Beets, use of acrolcin
Readucs of chlorinated!
hydrocarbons
Cane, use of mongoose to
control rats
Epidemics of poisoning.
panthkm in
SUGARCANE
Aldrin, use to control beetles
Insecticide usage on
BHC/liadane, use to control
pests
Losses due to insects
Biological control, use of
mongoose to control rats
Pentachlorophenol. use on
Simazine, use or.
183
209
211
212
519
84
88
88
124
135
216
310
51
84
*9
89
216
652
653
190
-------
SUBJECT INDEX
SUICIDE
Pesticide poisonings
Pesticide poisonings
Pesticide poisonings
Pesticide poisonings
Pesticide poisonings
Epidemiology of pesticide
poisonings :
Attempted, Paraquat ingestion
SUNFISH
DDT in
SURGERY
Obta'ning of samples, for
population studies
Pesticides in body tissues,
samples obtained in
Specimens of tissues,
obtained from
Interactions, effects of
surgical stress
Stress, effect on dicldrin
blood levels, humans
SURVIVE
Pesticides, effects on birds
Pesticides, effects on birds
Transportation of pesticides,
containers
DDT, effect on lake trout
Pesticides, effects on fish
Single pesticides - all
diseases
Temperature, effect on
pesticide toxicity
Combined chemicals, effects on,
mice
2,4,5-T; effects in rets
157
158
251
306
30S
314
373
120
SWEATING
Initial sigrr and symptoms of
intoxication 360
Organophosphorus pesticides,
effects 360
Oiganophosphorus compounds,
effects 364
Signs and symptoms in poisoning
cases 449
Cholinestcrasc inhibitors,
effects of poisoning 450
SWEET
Organochlorincs, use >o control
sweet potato weevil 55
255
385
496
525
530
25
179
193
209
210
253
432
546
666
Potatoes, insecticide
usage on
Potatoes, use of cyclodiencs on
Potatoes, naptalam, use on
SWELLING
Nitrogen compounds, paraquat
ingrrtion, effects on liver
SWINE
Vyrethrin, allethrin,
toxicity to
Use of mammalian species for
testing
SYNAPSE
Chlorinated hydrocarbons,
acctylcholinc, effect at
SYNERGISM
Carbamatcs. combination with
pyrethrin synergists
Need for knowledge on
EPN, malathion
Chemicals used to enhance
toxicity
Chemicals used as synergists
for pyrcthroids
Pyrcthrum sprays, effects
Toxicity
84
87
651
373
62
659
524
65
81
523
541
542
545
546
-------
SUBJECT INDEX
Mode of action of MDP compounds 554
MDP compounds
MDP compounds
SYSTEMIC
Insecticides, phorate,
disulfoton
Organochlorines
Herbicides
Carboxylic aromatic herbicides
Phenoxy herbicides
559
560
60
63
67
68
68
Vs surface-type pesticides 132
Insecticides, metabolism by
plants 133
Poisoning, pesticides 307
Effects, organophosphates 360
Effects, otganophosphates 361
Effects, inorganic arsenicals 362
Poisoning, effects on eye 366
Absorption. Bidrin, effects 367
Poisoning, organophosphates 369
Pentachlotophenol effects 370
Poisoning, pesticides 383
Effects, organophosphates 389
Percutaneous penetration 401
Poisoning, occupational
exposure . 415
Insecticides, ate in agriculture 610
Phosphairadon. use 653
TACHYCARDIA
Organophosphorus compounds.
effects 371
Pesticide poisonings, signs
and symptoms . 449
TAIL
Brown-tail moth, predators
to control 152
Defects, phenylmercuric
acetate, effect in mice 664
TAINT
Vegetables, use of BHC in
pest control 87
Potatoes, use of BHC,
production of 87
TANGERINE
Difolatan, occupational
dermatitis in groves 365
Dermatitis, in orchards in
Japan, due to Difolatan 399
TASTE
2,4-D in watnr, effect on
cattle water consumption 117
Impairment, phenoxy chemicals,
occupational exposure 350
Bitter. Baygon exposure 369
TASTELESS
Anticoagulant rodcnticides 72
DDT colloidal aqueous
suspensions 298
TEA
Crop, uage of insecticides 84
TEARING
Organophosphorus compounds,
effects 367
Precautions, pesticide
operators 444
Cholincster.ise inhibitors,
effects 446
TERATOGENS
Information needed on 262
Search for. in environment 601
Experimental factors to consider 658
Circumstances, influence of,
humans 659
Exposure to, humans,
production of malformations 659
192
-------
SUBJECT INDEX
Recognition of 661
Need for recognition of,
ways to recognize 662
TERATOGENESIS
Pesticides 10
Needed additional studies on,
Federal support for 16
Needed studies 241
Captan, folpet, difolatan 438
DNA alterations, chromosome
breaks 60S
Need for restriction of human
exposure 6S7
Methodologies'for tssting 653
Methodologies for testing 659
Testing 660
Need for monitoring of 662
Need for testing,
interactions in 663
Captan, fotpel, effect in
chicken embryos 664
Captan, effect in rabbits 664
Captan, Folpet, effect in mice 664
Caibary I, effect in beagle dogs 664
Kelthane, effects in mice 664
Oiganophosphatei, effects in
yolk sacs of chick embryos 665
Thiram, effect in hamsters 665
2,44-T; effect in mice 665
2,4-D esters 666
Need for studies, pesticides,
humans 674
Organophosphates, humans,
audits 675
TERMITES
Diddrifl.usefor 52
Qitordane, use for _ 53
Aldrin, chlotdane, dieldrin,
heptachlor, use for 53
Persistent insecticides, use for 54
Chlorinated hydrocarbons, use for 63
Creosote, ptntachloropheno!, use 65
Rice pests, use of aldrin 85
Sugarcane, BHC/lindar.e, use
to control 89
Damage from chemical to
control
Chlotdane, contamination of
well water
Pests, control by pest control
operators
Use of persistent pesticides
for control of
Fest control
TESTICULAR
Birds, effects of pesticides on
DDT, effect on growth of
cockerels
Dominant lethal test
THALLOTOXICOSIS
Symptoms
THICKNESS
DDE, effects on egg si «Us in
birds
DDT. effect on eggshell* in
birds
DDT, dieldrin, effects on
eggshells in birds
THROAT
Experimental respiratory
exposure to DDT, effects
Carbamates and carbamoyl
oximes, effect on mucous
membranes
Inorganic arsenicah, early
symptoms from ingestion
90
117
ISO
152
195
211
437
596
363
212
437
665
296
361
362
193
-------
SUBJECT INDEX
THROMBOCYTOPENIA
Blood dyscrasias. associated
with chlordane and gamma
benzene hexachloride 388
THYROID
Occupational exposure, pesticides,
radiation 255
lysfunctions, occupational
exposure, pesticides 351
TICKS
Pesi control service, pests
controlled 53
Pes!s, problems of 58
Repellents, use for
protection from 75
Important pests controlled
by pesticides 150
TIMBER
Regulation of commodities 55
DDT, use on 647
TINNITUS
FAA workers, occupational
exposure to orsanophosphorus
insecticides, pilots 414
TOLERANCE
Zero limits 10
Review of, adjustments to 11
Establishment of 12
Organophosphatex 64
Natural, rodenticides 151
Establishment, registration 238
Levels, foods 239
Poisoning cases 383
Zero, effects of 480
Administration of combinations
of pesticides 512
Theoretical DDT intake 519
Dkddrin inteSce 537
For piperonyl l-utoxide 542
TOMATO
Vegetable crops 87
Use of cyclodienes to control
pests 87
Fate of malathion residues,
food processing 141
Residues of L>DT, malathion,
carbaryl from, in food
processing 141
Resistant straws of plants,
development of 162
Parathion sprzying, exposure
of humans 445
Malcic hydrazidc, testing,
effects 642
Lindane, use for crops 650
TONGUE
DDT in oil, effect on humans 298
DDT solutions, slightly
anesthetic to 298
Acute DDT poisoning,
paresthesias of 359
Organic mercurial compounds,
poisoning by.
paresthesias of 362
Paraquat ingestion, ulcers of 373
TOPICAL
Effects, skin, organophosphatcs 360
Effects, carbamates 361
Effects, cholinestense
inhibitors 364
Effects. Paraquat, Dtquat 365
Contamination, effects on eye 366
Ophthalmic effects, carbamates
and carbamoyl oximes 367
Application TEPP, effects 369
Exposure, TEPP, effects 406
194
-------
SUBJECT INDEX
TOXIC
Assessment of, chemical
Assessment of, needed research
Needed replacements, pesticides
Potential, organophosphates
To plants, petroleum, kerosene,
cresote, turpentine
To fish, wildlife, DDT
substitutes
To mammals, chcmostcrilants
To swine, rotenone
Organophosphates
Fungicides, bactericides
To humans, animals, phcncxy
herbicides
To humans, warm-blooded
animals, aliphatic acid
herbicides
Amides
To rodents, humans, roilenticides
and mammalian biocides
To rodents, botanical
rodenticides
To warm-blooded animals,
fluoride rodenticides
To fish, rotenone
Lindane
Chemicals, effects on
non-target organisms
To budworm, zectran
Chemical, route of entry
Quantities, toxaphenc. effect
on fish
By skin absorption, pesticides
Pesticides, residues, intake
In soil, arsenic
Pesticides, introduction into
14
16
23
34
45
49
60
63
64
65
68
69
70
71
72
72
73
102
105
111
112
119
135
138
145
water system
Rodenticides
Levels, chlorinate*' hydrocarbons
Dose, exposure to TEPP,
endrin, parathion
Less persistent pesticides
Compound, approval of
Degradation products.
formation of
Materials, accumulation in
food chain
Sodium arsenite
Tofish, Dinoscb
Organochlorines, rffects on
molluscs
Antimycin A, effects
Potential, carbamates
Chemicals, use, education
needed
To animals, pesticides, LD-50
Effects, exposure to pesticides
Parathion. respiratory exposure,
humans
Effects, o,p '-DDD, humans
Thallium, effect*
Effect on liver, phenoxy
herbicides
Organophosphates
Acute myocarditis.
organophosphates
Effect on liver.
organophosphates
Administration of dose, time
period
146
151
155
156
161
173
174
192
203
205
208
213
233
237
259
260
296
301
309
350
356
371
373
393
195
-------
Stria
Agents, ingestion of,
by children
Effects, species variations
Ncrbormide, effects in rats -i
To rats, DEF (Folex)
Effects, DDT, fat in diet
To mice, paratWon. effect
of temperature
To monkeys, Satin, effect
of temperature
To rats, DDT, warfarin.
azinphosmethyt, effect of
temperature
Nitrophenols, effect of
temperature
To rats, DNOC, dinitro-o-phcnol
Parathion, humans, effect
of temperature
Ultraviolet light, conversion
of parathion to paiaoxon
OUT effects on liver
Protective equipment, humans
Chemicals in urine, blood
Photosensitive hepatic
porphyria, BHC ingestion
Responses to chemicals in food
Effects. EPN, malathion
Effects. EPN, malathion
Effects, dieldrin, physiological
interactions
Diet, effect on pesticides
Organophosphates, X-irradiation
Physical factors, effects
Piperonyl butoxide, effects
Effect, piperonyl butoxide
To plants, animals.
formaldehyde
SUBJECT INDEX
409
417
424
426
427
431
432
432
432
433
433
433
433
434
444
448
450
478
512
523
529
532
533
534
542
546
649
TOXICANT
Fungicides, bacteiicides
Metaldehyde, use
Fumigants
Use against mice
Insecticides, miticides
DDT, effect on lake trout
Exposure, r umans
Bidrin expcsure. human,
effects
Norbormid:, effect on Norway rat
Effect of t>t in diet, DDT
Effect of MDP compounds
Pipeiony! butoxide, MOP
compounds, eifects
Route of administration.
effects
Synergistic action of
TOXICITY
Scheme for denoting, need for
establishment
Degree of, need to identify
for user
Acute, organochlorincs.
potential
Refined oil.-, effects on plants
Mammalian, DDT substitutes
Mammalian, DDT substitutes
Synergist to increase, formulation
with pyrethrin, aDethrin
Systemic herbicides
To mammals, benzok acid
compounds
In toil, phthalamic acid
compounds
65
73
197
200
206
209
262
367
426
431
542
544
546
554
17
23
34
45
48
49
62
67
68
68
196
-------
SUBJECT INDEX
To plants, humans, animals,
aliphr.tic acid herbicides
To mammals substituted
phenol herbicides
To mammals, heterocyclic
nitrogen derivatives,
herbicides
To humans, dinitroaniline
herbicides
To mammals, miscellaneous
herbicides
Scheme, need to devise new
Testing, costs
Oral, zc.-tian
To humans, pesticides, factors
to consider
Health liazards
Of wastes, municipal and
industrial waste discharges
Soil contamination
Anticoagulant rodcnticidcs
Data, route of entry
Herbicides, aquatic and
terrestrial animals
Paraquat, Diquat
Dieldrin, crabs
To cats, anticoagulants
Acute, organochlorines,
potential
Pesticide, effect of diet on
LD-SO definition
Organophosphates
Dermal, parathkm,
methyl-parathion
Acute oral, dermal, phosphate
ester pesticides, LD-SO
Acute oral, dermal, chlorinated,
hydrocarbon pesticides. LD-SO 313
69
69
69
70
70
77
78
111
112
;?7
143
151
155
203
205
209
215
233
235
259
2%
307
312
313
Organophosphatcs, effects
Organochlorine
Pesticides, effects on
nervous system
Acute, species, LD-SO
Occupational
DDT, rats
Exposure, decontamination
Acute, techniques of
observations
Chronic, percutaneous
penetration
Hair, nail observations.
index of
Behavioral effects of pesticides
Behavioral
Clinical behavioral
Of pesticides, experimental
animals
Animals, humans
Pesticide, tissue culture
Acute, chronic
Acute, DDT
Pesticide, animals, factors
Species, effects on
Age. effect on
Sex, effect on
Disease, effect on
Nutrition, effect on
Temperature, effect on
Light, effect on
Pesticides selected for testing
Interactions, effects on
347
356
359
382
383
388
400
402
403
405
406
407
408
423
424
424
424
425
426
426
427
428
429
431
432
433
481
509
197
-------
SUBJECT INDEX
Research, enzyme induction.
metabolites
Interact ins. definition
Interactions
Of carboxy esters
Malathion
Malathion, rat
Of pesticides, effect of
enzyme induction
Research, enzyme induction
Exogenous physical factors
influencing
Diet, effect on
Temperature <*ffect on
Radiation., effect on
Insert, pesticide interaction
with synergists
Of synergists
Pipcrony' K xxide
Pipcronj'i butoxide, MDP
compounds
Synergistic, Freons, piperonyl
butoxide
&/-ergislic, p-'peronylb' toxidc
Oril. LD-50, pesticides
Oral. LD-50. pesticides
Oral, LD-50, pesticides
Oral, LD-50, pesticides
Oral, LD-50. pesticides
Oral. LD-50. pesticides
Oral. LD-50, pesticides
Oral, LD-50. pesticides
Oral, LD-50, pesticides
510
511
512
513
513
514
517
521
531
532
533
533
540
541
542
544
545
546
645
646
647
648
649
650
651
65*-*
653
Perinatal, pesticides in
human milk 674
TOXICOLOGY
Environmental, need to
compile and submit data 241
Complexities 246
Epidcmiological approach ,,- 251
Animal, skin . 401
Industrial, toxic stress 409
Pesticide, chlordane,
enzyme induction 517
Of synergists for pyrethroid
insecticide chemicals 541
Mammalian. MDP compounds 542
TOXIN
Effect on non-target
organisms 217
Liver toxins, ingestkm by
humans 262
Ingestion of. effects 358
Thallotoxicosis. symptoms 363
Organophosphorus compounds,
effects of poisoning by 369
Metabolism of. effects on 388
Cycasin, plant toxin, formation
of mutagenic metabolic
products from _ 594
TRACHEAL
Fumigants, entrance into
trachea or respiratory
system, use against
insects 61
TRANSFUSION
In severe poisoning C51
TRANSMUTATION
Environmental agents on
genetics 568
s-fRANSPLACENTAL
Chlorinated hydrocarbons 674
Passage of DDT. DDL 674
198
-------
SUBJECT INDEX
TRANSPLANT
Organochlorines 55
Regulation of imports of
Irish potatoes and
transplants 55
Studies of tumors 466
TRAP
Chemical attractants. use in 75
Crops, for controlling
insect pests 83
Light traps, use for insect
control 166
Manufacture, precautions 192
Light, use as insect traps 219
Sex phcronones. intact traps 2!9
TRAUMA
Obtaining tissue, blood samples
from iiuman population J85
Miscellaneous behavioral
changes, causes 418
Pilot, death, from 445
TRICHINOSIS
Interaction of DDT with, rats 429
Effect on storage of DDT.
DDE. rats 429
TF.OUT
Toxaphene, effect on 119
Effect of DDT on eggs of 209
DDT. effect on reproduction in 209
DDE, metabolite of DDT, in 209
DDT, metabolites, in 210
TSSTSE
Fly, sleeping sickness,
tranxmissixin 91
TUBER
Potato crops 87
Moth, DDT. for control of 87
TUMOR
Screening studies for,
induction - 10
Testing procedures, animals 465
Evaluation of animal 466
Interpretation of results 466
Benign 467
Induction, judgement
categories 468
Induction, judgement
categories 469
Induction, compounds judged not
posiuve 4/>9
Chcmica'i registered for u«e
on faxl crops 469
Induction, compounds judged
positite 470
Chemicals registered for use
on food crops 470
Chemknk registered but not
for use on food crops 470
incidence 473
Chemicals registered for use
on food crops 473
Chemicals registered but not
for use on food crops 473
Incidence 474
Chemicals registered for use on
food crops 474
Chemicals registered but not
for use on food crops 474
Incidence 475
Chemicals registered for use
on food crops 475
Chemicals registered but not
for use on food crops 4 /5
Benign, mice 482
Induction 483
Incidence, discussion of 486
Recording of, discussion of 487
Pathologic evaluation 488
Incidence, groups, chemicals 489
Animal studies, pesticide! 492
Expected percent of animals with 494
544
MDP compounds, production of.
lymi>hatic system
199
-------
SUBJECT INDEX
Study. Frcors. piperonyl
butoxkle 545
TUMORICEN1CITV
Categories for judging 461
Repofts of. pesticides 462
Index of potential
carcinogenkity -166
Animal data examined 468
DDT studies, animals, needed
research 471
Potential 472
Incidence of 473
Chemicals registered Tor tuc
on food crops 473
Chemicals registered but not
for use en food crops 473
Testing needed 476
Testing needed, pesticides,
food residues 478
Testing, need for 479
Reports of, pesticides 480
Recommendation for information
stonge, availability 480
In animals 482
Study for 488
Chemical groups, chemicals 489
Chemical groups, chemicah 490
Diethylcarbamates 491
Ethyl carbamate. Avadex 491
Chemical groups, chemicals 491
Animal studies, pesticides 492
Potential. MDP compounds 543
TURFGRASS
Inorganic fungicides, use on 66
TURNIP
Greens, limited markets for
pesticides 80
TYPHUS
D!)T. use in developing
nations, for control of 9
DDT. use in halting ej kiemit of 45
DI/r. use in control of 2%
High priority uses of
pesticides, for control of 472
DDT, use to control, benefits
from 472
ULCER
Peptic, occupational exposure
to aldrin, dieldrin 351
Paraquat Digestion, effect
on tongue, and
gastrointestinal tract 373
Prcetnptoymecl examinations
eyes 443
ULTR \SOUN >
Proposed for use against birds 83
Physical pest control methods.
ultrasonic energy 165
Proposed for pest control 167
ULTRAVIOLET
Light, use in traps for insects 166
Lfeht; 2,4,5-T presence 203
Light, environmental factors 249
Light, effect on oxidation of
organophosphoius pesticides 433
Light, conversion of paralhion
to paraoxon 433
UNCONTAMINATED
Estuaries, of importance for
marine food production 121
Compressed air, protection of
workers, occupational
exposure 153
Areas, barriers to prevent
spread of pesticides 199
200
-------
SUBJECT INDEX
IINE
p p '-DDA in. humans, p,p '-DDT
trctment
pj> '-DDA in. human*. P4> '-DDT
in bodyfat
Occupational exposure.
dkldrinin
Panquat, exaction in
Organophosphates, effect on
fjeni to-urinary «y;tcra
DDA in. metabolite of DDT
Paranitrophenol in.
metabolite of panthion
P-mtrophenoi in, parathion
exposure
Carbarylin
DD£ in. monkeys
Biolt gical fluids.
equilibration with brain
DDA in. metabolite of DDT.
humans
Dieldrin in. occupational
exposure
Indicator of exposure
Index of exposure
BHC ingisf *>n.
delta-wninotevulinic acid in
Oximes, excretion
Excretion of ascorbic acid,
6-b-hydroxycortisol hi
Enzyme induction measurements
DieUrinin
Excretion of MDP compounds
Excretion of MDP compounds
?90
291
350
370
373
3*8
388
402
403
427
447
447
447
447
448
450
4S3
520
520
527
547
548
VAGINAL
Testing
Testing. j«tfgn*ncy
determinations
VASCULAR
Diazinon poisoning, deaths.
pathology of organs
VEGETATION
PeneUauon of, by spraying
Intercuanges of pesticides
between '.vater and vegetation
DDT. concet. '.rations in
Control, granule formulations,
use for
VENTILATION
Reduction o' hazards to
employees
Panquat poisoning
Behavioral effects of
solvents, pjed for
Artificial respntion. use in
poisoning cases
VENTRICULAR
Yellow phosphorus ingestion.
EEC pattern simulating
infarction of left
ventricle
Sodnm fluoroacetate, death
bom fibrillation or cardiac
attest
DDT poisoning, animals,
death frort fibrillation
VERTEBRATE
Dynamics of ot^tnochlonnc
insecticides in
Amidase. degradation of
dtaetlKMle. less active
in human !hwt thin other
661
667
367
111
120
120
199
153
370
417
450
371
371
425
263
URTICARIA
Chlorinated hydrocarbons,
effects 446
17TERINE
DDT, methoxychlor. effect on
organ weight • 437
vertebrates 514
VINES
Chlorinated hydrocarbons,
use on 84
Sodium anenite. use as
potato vjae killer 205
201
-------
SUBJECT INDEX
VISIBLE
Light, use to control insects
Costs, of environmental
manipulation
Chromosome changes, visible
by microscopy
Chromosome break*, effects
on cells
Contamination of eye by
organophosphoni i
compounds, effects
Or ;anophosphorous compounds,
effects on
Organic mcrcuiial pesticides,
effects
Airplane pilots, effects on
Airplane pilot, effects on
Che linctt erase inhibitors,
effects on
Poisoning by oi.vinic
mercurial ft-.. gkidcs,
effects
VOMITING
DDT ingestion. human
DDT poisoning
Organophosphates, effects
Orgknophosphates, eye
con lamination .effects
Inorganic arsenical poisoning
Yellow phosphorus fatgcstion
Pesticides
ChlorLiated hydrocarbons
Economic poisons, effects
Dinitrophenot,
pentachlorophenol poisoning
166
304
569
588
361
367
368
406
445
446
448
298
359
360
36 1
362
371
419
446
449
450
WASP
Biological control, use of
parasites against olive
scale
21
WASTEWATER
Research and development needs 24
Treatment processes for
elimination of pesticides from 24
Research and development needs 103
Treatment processes for
elimination of pesticide* from 103
WATER
Persistent pesticides,
residues ir 9
Pesticide residues in,
restriction! 1!
Residues in. environmental
contamination 12
DDT in 13
Ground, need for data in 23
Need for standards 74
Dispersal of pesticides 25
Wash, contamination, industry 27
Oils on, for mosquito control 62
Organochtorines. insoluble in 63
Piscicides. use 73
Rice weevil, use of aldrin for 85
Need for standards 103
Route 116
2,4-D; contamination of well 117
Well, analysis for chemicals 117
Pollution of, surface runoff 118
Estuarine 120
Potable, supply 111
202
-------
SUBJECT INDEX
Standards, limits
Quality critcru
Treatment processes for
removing chemicals
2.44); removal from
Toxaphene, BHC. removal from
Removal of pesticides from
Irrigation, contamination of
Aldrin, dhtdrin in
Endrin in
2,4-D; analysis for efter
application
ODD, analysis for after
application
Municipal and industrial
Concentrations
Exposure of population
Malathion, removal by
Leaching of pesticides from
soil by
Leaching of pesticides
from soil by
Dieldrin in runoff
Introduction of pesticides in
Solutions of anticoagulants,
use for rodent control
Transportation, contamination
by accidental spills
Disposal of rinse water
Insect pathogens.
transport of by
Need for studying pesticides in
Pesticide levels in, program
to determine
Surface, pesticides in
Exposure of urbar population
topesticidciin
122
122
122
123
123
123
1 24
1 24
125
126
/ 76
127
128
138
141
143
144
145
146
151
157
1 59
163
169
170
171
172
v 'easurements of pesticides in 173
Pesticides in, concentration
in organism'. 179
Contaminated «ash, industry,
needed improvements 181
Leakage of pcricides in 192
Disposal of pesticides,
avoidance of 194
Contamination of, agricultural 195
Mosquito control 197
Transport vehicle for pesticides 198
Contamination. Dinoseb.
effects on mirine life 205
Fhytoplankton in 207
Marine invertebrates 208
Marine organisms, effect of
pesticides oa 210
Fish-eating buds, effect of
toxaphenc 211
Degradation of Antimycin A in 213
Management 218
Organophospnates. accidental
spills in 234
Samples, surveillance needed 242
DDT in, human exposure, effects 298
DDT in 326
Estimates for annual intake,
DDT plus DDE 384
Parathion exposure, removal of 400
DDT in diet, rats, effect
on ability to swi/.i in 433
Sodium sulfate in, therapy for
poisoning 450
Contamination, need to reduce 472
203
-------
SUBJECT INDEX
Pesticides in. legislative
needs
Pollutants, exposure of humans
Application form, (WML) water
irascible liquid. (WSO water
soluble concentrate
SoKibi; compounds, administration.
teratogenkity testing
WATERFOWL
Pesticides, management of
WATERSHED
Crops in. pvathion applied to
DDT. control of gypsy moth,
flies in
WEANLING
Acute loxicity of
anticholinesterasc
insecticides, weanling vs.
adult rats
DEF (Folex) loxicity to rats
Toxicity of DDT, effect of age
Methodologies for
teratogcniciry testing
WEATHERING
Metal salts, persistence in
soil, removal of by
Formulation and application
method, effect on pesticide
WHEAT
Growth retardants, effects
f
Losses due to insects
Grown in soils treated with
DDT, dieldrin, residues in
Resistant plants
Integnted control techniques
Avicides. growing of crops
on soil, residues
Pest. Hessian fly, host
resistance to pests
Timing of planting
480
598
645
2!3
144
209
427
427
427
658
45
143
74
86
133
162
167
214
217
environmental manipulations
Parathion in, epidemics of
poisoning
BHC contamination of.
ingcstion, humans
Linuron, use
WILDLIFE
DDT. DDE in
Need :o augment efforts to
protect
DDT substitutes, hazards to
Repo>ting of adverse effect on
Organ ^chlorines, effect on
Rode Uicidcs did mammalian
biocidcs
Pesticides in
Pest control of structures.
precautions
Seed treatments, effects
Herbk*d'*s, effects on
Paraquat, diquat, effects on
Organophosphatcs, hazards to
Rep Kting of hazards to
Polyc'ilorobiphenyb in
Poisoning investigation, need for
Anticholinesterase insecticides.
cumulative effects on, need
for evaluation
Cumulative effect of pesticides
on cholinesterase and
aliesterase activity in.
need for evaluation
WINE
Growers, occupational exposure
to arsenical insecticides,
effects
218
310
450
650
9
15
49
51
56
71
171
195
200
205
205
234
241
257
356
510
514
363
204
-------
SUBJECT INDEX
W1REWORMS
Aldrin, use to control
Methoxychlor, use
Cotton crops, cyclodienes
use to control
Cereals, use of BHC to control
Potatoes, use of cyclodiencs
to control
Tobacco, use of cyclodiencs to
control
2,4-D; effect on
WORMS
Eradication program for
screw worm
Eradication program for
screw worms
Cereal crept, use of
cyclodienes to control
Tobacco, use of DDT to control
foliagt pests
Death, after treatment of
ponds with DDT
Control of screw-worm fly.
induced sterilization
Chloroform, use for screw
worm control
51
51
84
85
87
89
204
82
83
85
89
208
219
e^At.
Parathion, use to control
YEAST
Acrylonitrilc, testing, effects
YOLK
DDT, effect on reproduction
in lake trout
Concentration of DDT in fish
eggs
Organophosphates, teratogcnic
when injected into yofk sac
of chick embryos
ZERO
Tolerance liruts
Tolerances, effect of
imposition of
DDT levels in pond
Robin population
Incidence, concept of
Incidence, testing procedures
Tolerance, effect of
imposition of
Dose spacing
ZYGOTE
Dominant lethal test
Dominant lethal test
652
639
209
209
665
10
11
120
211
393
465
480
493
596
597
205
-------
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310
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[BIBLIOGRAPHIC DATA i. KCj>ort NO. * 2.
SHEET BPA-540/9-69-Q02 (HEW)
4. Title nnJ Subtitle
Index to the Report of the Secretary's Commission on Pesticide
and Their Relationship to Environmental Health
7. Author(s) Sharon L. Valley, Ph.D., Toxicology Information Program
National Library of Medicine
9. Performing. Organization Name and Address
National Library of Medicine
8600 fockville Pike
Bethesda, Maryland 20014
12. Sponsoring Organization Name and Address
U.S. Department of Health, Education, and Welfare
Public Health Service
National Institutes of Health
3. Recipient's Accession No."
5. Report Date
! . 1969
6.
' No! rmmS r**n'™lon ePf'
10. Projcct/Taslc/Work Unit No.
11. Contract/Grant No.
13. Type of Report & Period
Covered
14.
15. Supplementary Notes
)6. Abstracts
The indexes in this publication were designed to assist users in' rapidly finding
information in "The Report of the Secretary's Commission on Pesticides and Their
% Relationship to Environmental Health", This publication consists of three indexes:
(•
•-'i
,
/} a Chemical Substances Index; a Subject Isii^^. nl
fe*
"• Key ttfords and Dccuaieti. Analysis. I7o. Descriptors
Too numerous to list,
7V. Uemifiers/Opea-Eoded Terns
7c. COSATI Field/Croup
^on»« M1
O BY ANM AND UNhSCt).
19. Security Class (This
Report)
UNCLASSIFIf-n
M J V I v^^n.-..-.* *'•"
20. >ccu.-s-y t'i.iss (This
21. No. of Pages
32. Price
Tills «>KM MAV I1H Kt-IMUMHirKD USCOMM-DC •'ei^T*
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