&EPA
Unrted States
Environmental Protection
Agency
Office of
Pesticides and Toxic Substance*
Washington DC 20460
April 1987
Pesticides
Guidance for the
Reregistration of
Pesticide Products
Containing TRIFLURALIN
as the Active Ingredient
-------
GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
TRIFLURALIN
AS THE ACTIVE INGREDIENT
CASE NUMBER: 0179
CAS NUMBER: 1582-09-8
April 1987
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D. C. 20460
-------
TABLE OF.CONTENTS
I. Introduction . ,.
II. Chemical(s) Covered by this Standard ,
A. Description of Chemical
B. Use Profile
C. History of Significant Regulatory Actions
III. Agency Assessment 8
A. Summary
B. Preliminary Risk Assessment
C. Other Science Findings
D. Tolerance Reassessment
IV. Regulatory Position and Rationale 27
A. Regulatory Positions
B. Criteria for Registration
C. Acceptable Ranges and Limits
D. Required Labeling
V. Products Subject to this Standard 39
VI. Requirement for Submission of Generic Data 40
A. What are generic data?
B. Who must submit generic data?
C. What generic data must be submitted?
D. How to comply with DCI requirements
E. Procedures for requesting a change in protocol
F. Procedures for requesting extensions of time
G. Existing stocks provisions upon suspension or
cancellation
VII. Requirement for Submission of Product-Specific Data . . 45
VIII. Requirement for Submission of Revised Labeling 46
IX. Instructions for Submission 47
A. Manufacturing use products (sole active)
B. End use products
C. Intrastate products
D. Addresses
-------
APPENDICES
I. DATA APPENDICES
Guide to Tables
Table A
Table B
II. LABELING APPENDICES
Summary of label requirements and table
40 CFR 162.10 Labeling Requirements
Physical/Chemical Hazards Labeling Statements
Storage Instructions
Pesticide Disposal Instructions
Container Disposal Instructions
III. USE INDEX APPENDIX
IV. BIBLIOGRAPHY APPENDICES
Guide to Bibliography
Bibliography
Addendum to the Bibliography
V. FORMS APPENDICES
EPA Form 8580-1 FIFRA §3(c)(2)(B) Summary Sheet
EPA Form 8580-6 Certification of Attempt to Enter- Into an
Agreement with Other Registrants for Development
of Data
EPA Form 8580- Formulator's Exemption Statement
-------
I. INTRODUCTION
The Registration Standards Program
EPA has established the Registration Standards program
in order to provide an orderly mechanism by which pesticide
products containing the same active ingredient can be reviewed
and standards set for compliance with FIFRA. The standards
are applicable to reregistration and future applications for
registration of products containing the same active ingredient.
Each registrant of a product containing an active ingredient
subject to this Standard who wishes to continue to sell or
distribute that product must bring his product and labeling
into compliance with FIFRA, as instructed by this Standard.
Pesticides have been grouped into use clusters and will be
reviewed on the basis of a ranking scheme giving higher
priority to (1) pesticides in clusters used on food and feed
crops; and (2) pesticides produced in large volumes.
The Registration Standards program involves a thorough
review of the scientific data base underlying a pesticide's
registration. The purpose of the Agency's review is to
reassess the potential hazards arising from the currently
registered uses of the pesticide; to determine the need for
additional data on health and environmental effects; and to
determine whether the pesticide meets the "no unreasonable .
adverse effects" criteria of FIFRA. In its review EPA identifies
1. Studies that are acceptable to support the data
requirements for the currently registered uses of the
pesticide.
2. Additional studies necessary to support continued
registration. The additional studies may not have been
required when the product was initially registered or may be
needed to replace studies that are now considered inadequate.
3. Labeling revisions needed to ensure that the product
is not misbranded and that the labeling is adequate to protect
man and the environment.
The detailed scientific review, which is not contained
in this document, but is available upon request, focuses on
the pesticide active ingredient. The scientific review
primarily discusses the Agency's evaluation of and conclusions
from available data in its files pertaining to the pesticide
-------
active ingredient. However, during the review of these data
the Agency is also looking for potential hazards that may be
associated with the end use products that contain the active
ingredient. The Agency will apply the provisions of this
Registration Standard to end use products if necessary to
protect man and the environment.
EPA's reassessment results in the development of a
regulatory position, contained in this Registration Standard,
on the pesticide and each of its registered uses. See
Section IV - Regulatory Position and Rationale. Based on its
regulatory position, the Agency may prescribe a variety of
steps to be taken by registrants to maintain their registrations
in compliance with FIFRA. These steps may include:
1. Submission of data in support of product registration;
2. Modification of product labels;
3. Modifications to the manufacturing process of the
pesticide to reduce the levels of impurities or contaminants;
4. Restriction of the use of the pesticide to certified
applicators or other specially trained individuals;
5. Modification of uses or formulation types; or
6. Specification of packaging limitations.
Failure to comply with these requirements may result in
the issuance of a Notice of Intent to Cancel or a Notice of
Intent to Suspend (in the case of failure to submit data).
In addition, in cases in which hazards to man or the
environment are identified, the Agency may initiate a special
review of the pesticide in accordance with 40 CFR Part 154
to examine in depth the risks and benefits of use of the
pesticide. If the Agency determines that the risks of the
pesticide's use outweigh the benefits of use, the Agency
may propose additional regulatory actions, such as cancellation
of uses of the pesticide which have been determined to cause
unreasonable adverse effects on the environment.
-------
EPA has authority under the Data Call-in (DCI) provisions
of FIFRA sec. 3(c)(2)(B) to require that registrants submit
data to answer our questions regarding the chemical, toxicological,
and environmental characteristics and fate of a pesticide.-
This Registration Standard lists the data EPA believes are
necessary to resolve our concerns about this pesticide.
These data are listed in the Tables A and B in Appendix I.
Failure to comply with the DCI requirements enumerated in
this Registration Standard may result in issuance by EPA of a
Notice of Intent to Suspend the affected product registrations.
Registrants are reminded that FIFRA sec. 6(a)(2) requires
them to submit factual information concerning possible unreason-
able adverse effects of a pesticide at any time that they
become aware of such information. You should notify the
Agency of any information, including interim or preliminary
results of studies, if those results suggest possible adverse
effects on man or the environment. This requirement continues
as long as your products are registered by the Agency.
-------
II. CHEMICAL COVERED BY THIS STANDARD
A. Description of the chemical
The following chemical is covered by this Registration
Standard.
Common Name: trifluralin
Chemical Name: alpha,alpha,alpha-trifluoro-2,6-dinitro-N,
N-dipropyl-p-toluidine
Empirical Formula: C]_3H]_6F3N304
Chemical Abstracts Service (CAS) Number: 1582-09-8
OPP(Shaughnessy) Number: 036101
Trade Names: Treflan, L-36352, Crisalin, Su Seguro Carpidor,
Trefanocide, Treficon, TR-10, Triflurex, Trim, Ipersan,
Sinflouran, Ipifluor
Physical Characteristics: Yellowish-orange crystalline solid
at room temperature; no appreciable odor
Molecular weight — 335.3
Melting point — 42.0 to 49.0 °C
Solubility at 25 °C — >50 grams (g)/100 ml
in acetone, 81 (g)/100 ml in xylene,
0.00003 (g)/100 ml (0.3ppm) in water
Vapor pressure — 1.1 x 10~4 mm -Kg at 25° C
Stable to hydrolysis at pH 3, 6, and 9
B. Use Profile
Trifluralin is a selective preemergent herbicide registered
for the control of annual grasses and certain broadleaf weeds.
Trifluralin's mode of activity involves inhibition of root and
shoot growth when absorbed by the roots of germinating plants;
it does not directly inhibit seed germination. Trifluralin
was first registered in 1963 and is available as a 94.5, 95,
96, and 98 percent active ingredient technical product and
as a 20, 44.5, and 46 percent active ingredient formulation
intermediate for formulating trifluralin end-use products.
Trifluralin is formulated as a granular, wettable powder,
emulsifiable concentrate, and a pressurized dust. The emulsifiable
concentrate is the most widely used formulation. Registered
trifluralin products are formulated with trifluralin as the
sole active ingredient, in combination with other active
ingredients, with fertilizers, or with both.
The major agricultural uses of trifluralin are for pre-
emergent weed control in the production of soybeans and cotton and
various vegetable crops. The chemical is also registered for use after
planting on ornamental trees and shrubs, roses and other flowers,
4
-------
and fruit and nut trees. In addition, trifluralin is registered
for various nonagricultural sites, such as rights-of-way,
domestic outdoor and industrial sites. Of the total amount
of trifluralin applied in the United States, approximately
65 percent is applied to soybeans, 19 percent to cotton, 8
percent to sunflowers, 4 percent to wheat and the remaining
6 percent to vegetable crops, dried peas, beans and nonagricultural
sites. Application rates for terrestrial food crops and
ornamental plants range from 0.25 to 4.0 pounds active ingredient
per acre depending upon soil texture, average rainfall, and
weed species. Application rates range from 0.5 to 16 pounds
active ingredient per acre for terrestrial noncrop uses.
Trifluralin is applied by low pressure ground spraying
equipment, subsurface layering equipment, irrigation systems
and in a few instances by aerial equipment. Soil incorporation
within 24 hours after application is recommended for most
uses of trifluralin. For some products, surface application
followed by irrigation is recommended.
The Blanco Products Division of Eli Lilly & Company
is the domestic producer of trifluralin. Foreign producers
of trifluralin are Industria Prodotti Chimici S^p.A. of
Italy, Makhteshim-Agan of Israel, and Agrotran of Guatemala.
C. History of Significant Regulatory Actions
On August 30, 1979, the Agency initiated a Special
Review (formerly known as Rebuttable Presumption Against
Registration) of all pesticide products containing trifluralin
(44 FR 50911). The Agency had determined that a contaminant
of trifluralin belonging to the N-nitrosamine chemical class,
N-nitroso-di-n-propylamine (NDPA), met the oncogenic risk
criterion set forth in 40 CFR 162.11. (The Special Review
risk criteria and procedures have been revised and are now
found in 40 CFR 154. ) Simultaneously, the Agency issued a
Notice of Preliminary Determination which set forth regulatory
options for addressing the risks of exposure to trifluralin's
N-nitrosamine contaminant.*
*The Special Review process is typically conducted in steps
beginning with issuance of a Notice of Intent to Initiate a
Special Review (Position Document [PD] 1) which solicits
comments and information on the identified risks and the
economic, social and environmental benefits of the pesticide's
use. After this step, the Agency evaluates the risks and
benefits and proposes a regulatory position in a second
position document (PD 2/3). In the case of trifluralin,
these steps were combined because the Agency had already
collected sufficient information to make an immediate risk/benefit
determination.
-------
In its PD 1/2/3, the Agency proposed to cancel the
registrations of products containing trifluralin unless
registrants instituted quality control measures in the manufacturing
process to reduce N-nitrosamine contamination levels to no
greater than 1 part per million (ppm). The Agency proposed
that registrants modify labeling of their products to reflect
less than 1 part per million (ppm) N-nitrosamine contamination.
In addition, the Agency proposed that the registrants
would need to perform additional testing of trifluralin for
reproductive effects, teratogenicity, and mutagenicity (including
heritable spindle effects). When the PD 1/2/3 was issued,
the principal registrant, Blanco Products Company, had already
instituted manufacturing methods to reduce the NDPA contamination
level to less than 1 ppm NDPA, and was also conducting a.
chronic feeding study to assess oncogenic effects due to
administration of trifluralin with an NDPA concentration of
less than 0.01 ppm, the limit of detection.
Following issuance of the PD 1/2/3, the registrant submitted
both comments on the Agency's risk assessments and the results
of its trifluralin chronic feeding study. This study indicated
that high doses of trifluralin, with NDPA levels less than
0.01 ppm, are associated with a statistically significant
increase in tumors of the kidney, bladder, and thyroid of rats when
compared to controls. As a result of the registrant's comments
and the review of the chronic feeding study, the Agency recalculated
and reevaluated the dietary and worker exposure to nitrosamines
and trifluralin and the oncogenic risks associated with
these exposures. The Agency determined that the estimated
overall risks associated with exposure to trifluralin itself,
or to the NDPA impurity in tifluralin at the allowable level,
were not unreasonable. A PD 4 was issued in July 1982
(47 FR 33777)* stating that the benefits of trifluralin
outweighed the identified risks and that registrants of
products containing trifluralin could maintain their registrations
under the following conditions:
*Both the PD 1/2/3 and the PD 4 are available from the Agency
upon request.
-------
a. All registrants of technical trifluralin (present
and future) must submit Confidential Statements of
Formula (CSF) that reflect a total N-nitrosamine concentration
of no greater than 0.5 ppm. The registrants must also
advise the Agency of the quality control procedures instituted
to assure that the level of total N-nitrosamine stated on
the CSF is not exceeded. In addition, registrants must
maintain accurate quality control records on these products
and make such records available to the Agency on demand.*
b. Registrants must perform mutagenicity testing on
trifluralin, including an assessment of whether trifluralin
has the capacity to disrupt formation or function of the
spindle apparatus in dividing cells.*
c. Registrants must perform testing of trifluralin for
reproductive and teratogenic effects.*
d. Registrants must conduct a field monitoring study to
assess potential toxic effects to aquatic organisms, since,
in light of new data and a reevaluation of existing information,
the Agency determined that trifluralin could reach aquatic
environments through soil runoff and, because of bioconcentration
abilities, could be harmful to fish and mollusks.*
*These requirements have since been complied with. Appropriate
information or studies have been submitted to the Agency with
the exception of the study to assess the effects on spindle
cells, for which the Agency, in cooperation with mutagenicity
testing experts, is attempting to develop a suitable protocol.
7
-------
III. AGENCY ASSESSMENT
Summary
The Agency has reviewed, to the extent practicable, the
existing data base submitted in support of the registration
of triflura.lin. A largely complete set of toxicity
studies, including long-term chronic feeding and oncogenicity
data, were submitted to the Agency at a time that was too
late for full reviews to have been completed and subsequently
included in the Standard. These data therefore have not been
included in the Bibliography to this Standard,- but may be
cited to support registration of products containing trifluralin,
subject to possible questions about their validity. The data
which have been fully reviewed are included in the Bibliography
to this Registration Standard and may therefore be cited to
support the registration of any of the currently registered
trifluralin.products without questions as to the Agency's
present view regarding their validity. A partial list of those
studies not yet reviewed may be found in an addendum
to the Bibliography. Based on the the review of the data
described in the Bibliography, the Agency has reached the
following conclusions.
(1) Trifluralin poses a limited oncogenic risk from
dietary and worker exposure. The pesticide is
classified as a Category C (possible human) carcinogen
based on the following:
(a) Trifluralin was associated with an increased
incidence of malignant tumors of the renal pelvis
of the kidney and thyroid gland of male rats,
. which was statistically significant at the highest
dosage administered. A statistically significant
increase in the incidence of combined malignant and
benign urinary bladder tumors also was observed in
female rats 'at the high dose.
(b) Structural analogs of trifluralin have been reported
to cause similar effects in rodents.
(2) At present, the Agency's view is that trifluralin's
benefits are not outweighed by its risks.*
*The known risks of exposure to trifluralin are discussed in
this assessment. A detailed quantitative benefits analysis
was completed for the trifluralin PD 1/2/3, and may be found
in Part III of that document.
8
-------
As a result of this review, the Agency has identified
missing data needed to evaluate the environmental and human
health risks associated with the use of trifluralin. These
data must be developed in order to maintain registrations
of products or register new products containing trifluralin,
The following summarizes the data gaps, including product
chemistry information. Please note that this is only a
summary; more details can be obtained by referring to Table
of the Data Appendices.
SUMMARY OF DATA GAPS -- TRIFLURALIN
Product Chemistry
Product Identity
Analysis and Certification
of Product Ingredients
Physical and Chemical
Characteristics
Residue Chemistry
Metabolism — plant and animal
Storage Stability
Magnitude of Residues for
Various Commodities
Environmental Fate
Photodegrat ion
Metabolism - lab
Mobility
Dissipation - field
Accumulation
Toxicology
Repeated Dose Study in rodents
(to identify NOEL for
nephrotoxic effects)
General Metabolism
Dermal Penetration
Wildlife and Aquatic Organisms
Acute Tbxicity to Estuarine
and Marine Organisms
-------
The Agency has also determined that label revisions must
be made in the following areas:
"Environmental hazards
"Irrigation water restrictions
"Hazards to children and domestic animals
Section C of this Part of this Registration Standard contains
a discussion of the Agency's review which resulted in these
determinations. Part II of the Registration Standard contains
the required wording for the labeling revisions.
Preliminary Risk Assessment
To assess the risks associated with trifluralin, the
Agency reviewed the existing data base.* This included the
review of studies conducted for oncogenicity, mutagenicity,
teratogenicity, reproductive effects, and metabolism. Based
on these studies, risks from dietary exposure.and worker
exposure have been evaluated. It should be noted that these
risk estimates were originally calculated in the early 1980's when
trifluralin was undergoing a Special Review because trifluralin
products contained potentially significant carcinogenic
N-nitrosamine contaminants. As discussed in Part II, C. of
the Registration Standard, the total N-nitrosamine contaminant
level in technical trifluralin has been reduced to levels no
greater than 0.5 parts per million (ppm). These levels are
not of toxicological significance in evaluating the risks of
exposure to trifluralin. This preliminary assessment therefore
focuses on effects observed from exposure to trifluralin
itself. (The only exception is the dietary risk which was
estimated taking exposure to both trifluralin and N-nitrosamines
into account.) The following is a summary of the risk assessment.
*With .the exception of the studies listed in the addendum
to the Bibliography.
-10
-------
(1) Oncogenicity Studies
Rat Studies In its evaluation of trifluralin the Agency
reviewed three rat oncogenicity studies.
(a) No oncogenic effects were observed in a study
(Eli Lilly, 1966) with Sprague-Dawley rats
administered 0, 200, 1000, or 2000 ppm trifluralin
in the diet for two years. The NDPA (N-nitroso-
di-n-propylamine) content of the test substance
is unknown. The Agency's Carcinogen Assessment
Group (CAG) determined that this study was adequate
to perform a safety evaluation.
(b) In a 1978 study conducted by the National Cancer
Institute (NCI), Osborne Mendel rats were fed 0,
3250, or 6500 ppm trifluralin for 78 weeks,
followed by observation for an additional 33
weeks on a control diet. It was determined that
the trifluralin technical used in this study was
contaminated with a N-nitrosamine (NDPA) at
levels large enough (84-88 ppm) to render interpretation
of compound-related effects equivocal. Neoplasms
of the kidney, urinary bladder, and thyroid, as
well as chronic inflammation of the kidneys,
were observed in this study. The urinary tract
tumors occurred in the control group with a fre-
quency similar or greater to that demonstrated
in the dosed groups. However, due to the small
number of rats in the treated groups actually
examined .(only 11 - 12 out of 50 test animals),
it is not possible to make valid comparisons
.between the two groups. The data on thyroid
tumors were determined to be equivocal and failed
to demonstrate any possible dose-related effect.
In summary, the Agency determined that this
study was not adequate to demonstrate the oncogenicity
of trifluralin, and therefore not adequate for
regulatory purposes.
11
-------
(c) Fischer 344 rats were administered trifluralin
in the diet for two years at concentrations of
0, 813, 3250, and 6500 ppra (Eli Lilly, 1980). The
amount of NDPA contaminant present in the trifluralin
was determined to be less than 0.01 ppm. Results
of this study showed that trifluralin produced
elevated incidences of:
"malignant neoplasms of the renal pelvis of the kidney
in all male dose groups, but statistically significant
at the high dose level only (p<0.05);
°combined benign and malignant neoplasms of the
bladder in in the mid and high dose females,
again statistically significant at the high
dose level only (p<0.05);
The following table summarizes the number of
tumor-bearing animals for each tumor type:
Tumors of the Transitional Epithelium of the Urinary Tract
Dose (ppm) 0
Sex M F
Number of rats 60 60
Papilloma of
the bladder 0 0
Carcinoma of
the bladder 0 0
Carcinoma of the
renal pelvis 0 0
0 0
813
M F
59 60
1 0
0 0
2 0
3 0
3250
M F
60 60
1 1
0 0
3 0
4 1
6500
M
60
1
0
6
7
F
60
3
2
0
5
Note: Urinary bladder hyperplasia was looked for histologically
but, with the exception of the renal pelvis, there was no
compound related increase in incidence. In fact, there was
minimal response in all groups.
12
-------
°In addition to the urinary tract tumors, there was
an increase in follicular cell adenomas and carcinomas
of the thyroid, which were significant at the high
dose in males (p<0.05). There was no significant
increase or dose-related trend for females.
The following table summarizes the number of tumor-bearing
animals for each tumor type:
Follicular Cell Neoplasms of the Thyroid
Dose (ppm)
Sex
Number of rats
Follicular Adenoma
Foil. Papillary Ad.
Foil. Cystadenoma
Foil. Carcinoma
0
M
60
1
2
0
2
5
F
60
0
0
0
0
0
813
M
59
0
0
0
1
1
F
60
1
0
0
0
1
3250
M
59
3
2
0
3
8
F
60
0
0
0
1
1
6500
M
60
10
0
2
1
13
F
60
1
1
0
1
3
For this study, the Agency also examined the effects of
ingestion of the compound on general health, survival,
weight gain, food consumption, and efficiency of food
utilization. There were no observed treatment-related
effects on appearance or behavior throughout the study,
except that body weight gain was reduced at the two
highest doses. (Survival was generally unaffected by
treatment except for high dose females at 24 months.)
Mouse Studies In its evaluation of trifluralin,
considered two mouse studies.
the Agency
(a) B6C3F1 mice were fed trifluralin
dosages of 0, 2375, and 5000 ppm
followed by 12 weeks observation
(NCI, 1978). In the female mice
significant increase occurred in
carcinomas (12/47 and 21/44 at the mid and high
dose respectively), and lung adenomas (6/43
and 3/30 at the mid and high dose respectively)
in the diet at
for 78 weeks,
on a control diet
a statistically
hepatocellular
13
-------
Squamous cell carcinomas of the forestomach were also
observed in female mice at both dosage levels
(4/45 and 1/44), but were not statistically significant
when compared to controls. However, because these
tumors are quite rare, (the historical background
was 0/1985), NCI considered the squamous cell
carcinoma of the stomach was a biologically significant
finding and therefore supplementary evidence of
the oncogenic potential of trifluralin. No tumors
were observed in the male mice.
It was determined that the N-nitrosamine (NDPA)
content of the technical trifluralin used in this
study exceeded 80 ppm (the contamination level could
have been significantly higher because the test
substance was not sampled until three years after
completion of the study). After reviewing NDPA
carcinogenicity studies which resulted in compound-
related tumors of the same type, the Agency concluded
that the elevated incidence of hepatocellular
carcinomas in the female mice was due principally to
exposure to the N-nitrosamine contaminant. The
Agency could not establish with any certainty whether
the other tumor types may have been caused by the
contaminant. This study was therefore determined
to be insufficient for regulatory purposes.
(b) In 1980, Eli Lilly repeated an oncogenicity study
using B6C3F1 mice with trifluralin containing NDPA
at levels unlikely to produce a tumorigenic response
(less than 1 ppm). In this two-year study, the
mice were fed trifluralin in the diet at concentrations
of 0, 563, 2250, and 4500 ppm. This study was
negative for oncogenic effects from trifluralin, and
determined to be adequate for regulatory purposes.
Other Data
Structure-Activity Correlations Trifluralin is a dinitroaniline
compound closely related to two other pesticide active ingredients,
profluralin and ethalfluralin. Although profluralin is no
longer manufactured, available data submitted to the Agency
demonstrated that profluralin in subchronic feeding studies
in rats and dogs demonstrated increased relative liver and
thyroid weights and numerous adverse effects on the kidney.
14
-------
Ethalfluralin demonstrated an oncogenic potential at
2^250 ppm when tested in Fischer 344 rats at dietary levels
of 100, 250, and 750 ppro for two years. There was a dose
related increase in fibroadenoinas of the mammary gland at
the mid and high dose ranges for females. The increase, however,
is not an unusual finding in aging rats of this strain, and
such effects have not been observed in any studies using
trifluralin. Further, there were insufficient measurements
of hematology, clinical chemistry, and urine throughout the
study. Ethalfluralin demonstrated a negative oncogenic
response when tested in the B6C3F1 mouse at 100, 400, and
1500 ppm for two years. It was a weakly positive mutagen in
the bacterial cultures of S. typhimurium and E. coli, but
negative in unscheduled DNA synthesis and L5178Y mouse lymphoma
cell.assays.
Metabolism Studies The collective data on profluralin,
ethalfluralin, and trifluralin demonstrate similar patterns of
excretion, with approximately 25-30% of the administered dose
eliminated via urine and the remainder via feces. They
demonstrate hemolytic effects at high doses with apparent
adverse effects on the kidney at lower levels.
Three structurally similar urinary metabolites of
ethalfluralin and trifluralin have been identified in rats.
Two of trifluralin's metabolites (one of which was identical
to an ethalfluralin metabolite) were administered in the
diet to Harlan rats at 200 and 2000 ppm for 90-105 days.
One of the metabolites produced adverse kidney effects (e.g.
hyaline degeneration). These effects were observed at >_200
ppm, predominantly in males. The other produced an increased
incidence (at the high dose in males) of renal pathology
with hyaline degeneration of the convoluted tubules, chronic
pyelonephritis and calculi in the urinary bladder.
However, the Agency has determined that these data are
not sufficient to characterize the general metabolism of
trifuluralin in animals and is requiring metabolism data
which are sufficient to isolate and characterize the metabolites
which are excreted via the urine, formed in the urinary
tract, and/or absorbed via the urinary tract.
15
-------
Non-oncogenic response in rats
Evaluation of the available data from the long-term
feeding studies in rats for trifluralin strongly suggest
that trifluralin is a nephrotoxic compound that induces
formation of renal calculi, significant increases in hyperplasia
of the pelvic epithelia, and significant increases in chronic
progressive nephrosis (CPN). In particular, the study with
Fischer 344 rats (Eli Lilly 1980) also revealed clinical
chemistry findings such as increased blood urea nitrogen
(BUN) levels at the lowest dose tested (813 ppm), and increased
creatinine excretion at the mid dose range (3250 ppm). These
findings are summarized in the following table which includes
the type of effect observed and the number of animals affected:
Renal Pelvis CPN, Hyperplasia and Calculi
in Fischer 344 Rat (Eli Lilly, 1980)
813
3250
6500
Sex: M F M • F MF MF
No. of Rats: 60 60 59 60 60 60 60 60
Hyperplasia: 01 1 3 11 1 23 23
CPN: 37 27 50 23 51 21 54 50
Calculi: 3 9 8 27 20 35 43 43
Hematology findings in this study also revealed hemolytic
changes which may be related to renal dysfunction. Finally,
there were increased relative liver, kidney, and testes
weights of males and of the liver and thyroid of females at
the mid dose range. At the high dose in females, increased
relative kidney and adrenal gland weights were observed.
With regard to the effects on the thyroid, it should be noted
that there is evidence that the changes in thyroid weight
and structure observed at high dosages may be a specific
physiological response to renal dsyfunction (DeGroot et.al.,
Endocrinology, Vol. I, 1978). This reference indicates that
renal dysfunction in humans can lead to alteration of thyroid
function by affecting thyroid iodide levels and metabolic
processes. Humans with chronic kidney disease are generally
hypothyroid and often develop goiter. Increases in relative
thyroid weight observed at 2.3200 ppm in the 1980 Eli Lilly rat
study may be indicative of this response.
16
-------
Additional data are being required to determine a NOEL
for adverse kidney effects in the rat since the clinical
chemistry, hematology, and urinalysis measurements in the
existing data base are inadequate.
Mutagenic studies
No evidence of mutagenicity was observed when trifluralin
was tested in a rat dominant lethal assay, Saccharomyces
cereviscae assay, DNA repair assay, or SCE assay using Chinese
hamster cells. The Agency concluded in its Special Review
of trifluralin that additional data to assess risks from
spindle fiber effects were needed. However, this data requirement
is being deferred until the Agency can develop an appropriate
testing protocol. Current test systems are not adequate or
or sufficiently sensitive to assess risks from spindle effects.
The Agency is consulting with experts in the field of mutagenicity
testing in order to develop a suitable protocol.
Teratogenic and reproductive effects studies
Teratology studies conducted in the rat and the rabbit
show no evidence that trifluralin is teratogenic. In the
rat, the maternal toxicity NOEL was 225 mg/kg/day. Decreased body
weight and food consumption were observed at 1000 and 475
mg/kg/day. The developmental toxicity (fetotoxicity) NOEL
was 475 mg/kg/day based on decreased mean body weight at
1000 mg/kg/day. There were no teratogenic effects observed
at doses up to and including 1000 mg/kg/day, the highest
dose administered.
In the rabbit, the NOEL for maternal toxicity was 100 mg/kg/day.
Anorexia and cachexia with resulting abortion were observed at
dosages of 225 and 500 mg/kg/day. Developmental toxicity
(fetotoxicity) observed at 500 mg/kg/day included depressed
fetal weight and an increased number of fetal runts. There were
no teratogenic effects observed at doses up to and including
500 mg/kg/day, the highest dose administered.
A 2-generation reproductive effects conducted with rats
demonstrated that trifluralin does not impair reproductive
ability. In this study, CD rats were administered 0, 200,
630, and 2000 ppm trifluralin in the diet. A reproductive
effects NOEL was established at 2000 ppm. The systemic NOEL
was 200 ppm, and the systemic LOEL (lowest-observed-effect-level)
was 630 ppm, based on decreased body weights.
17
-------
Acute Toxicity
Acute toxicity studies show that trifluralin is not
acutely toxic to animals tested. The herbicide has been tested
in animals via oral, dermal inhalation and ocular routes
of exposure, and the results show only minor effects. The only
remarkable acute toxicity finding is that trifluralin is a
skin sensitizer; that is, it may produce allergic reactions in
certain people.
Ecological Effects
Available data show that trifluralin is essentially
non-toxic to avian species and does not impair avian reproduction.
In studies with coldwater and warmwater finfish and aquatic
invertebrates, there is evidence that trifluralin is highly
toxic to these organisms.
Environmental Fate
Except for hydrolysis, the environmental fate data on •
trifluralin do not meet the Agency's current testing standards.
The environmental fate characteristics of trifluralin are therefore
largely inconclusive. However, the available data do not suggest
that trifluralin has potential for leaching to ground water.
Risk Assessment
Trifluralin is oncogenic with a cancer potency estimate
(Q!*) of 7.7 x 10~3 (mg/kg/body weight/day)'1. In
accordance with the Agency's 1984 Proposed Guidelines for
Carcinogen Risk Assessment (49 FR 42694, November 23, 1984),
the Agency has classified trifluralin as a Category C carcinogen,
that is, a possible human carcinogen.
These guidelines categorize the evidence on carcinogenicity
of chemicals in terms of how likely it is that the chemical
is a human carcinogen. Under this scheme, Group A, "Human
Carcinogen," is reserved for those chemicals for which there
is sufficient evidence of carcinogenicity from human epidemiological
studies. Group B, "Probable Human Carcinogen," is divided
into subgroups 1 and 2. Group Bl requires some human epidemiological
evidence.
Group B2 is said to be an appropriate categorization if
there is "sufficient evidence" of the chemical's carcinogenicity
from animal studies. "Sufficient evidence" is defined as
18
-------
an increased incidence of malignant tumors (or combined malignant
and benign tumors) — (a) in multiple species or strains, (b) in
multiple experiments, or (c) to an unusual degree with regard to
incidence, site or type of tumor, or age at onset. Group C
("possible human carcinogen") is said to be appropriate if
there is, among other things, "definite malignant tumor
response in a single well conducted experiment"; that is,
"limited evidence" from animal studies. (There is also a
Group D ("Not Classified") and a Group E that is reserved
for chemicals shown to be noncarcinogenic in animal and/or
human studies. )
EPA has decided to categorize the animal-study evidence
of trifluralin1s carcinogenicity as "limited," rather than
"sufficient," because the positive results were limited to one
strain of one species tested (the Fischer 344 rat in the
1980 Eli Lilly study). In addition, trifluralin was negative
for oncogenicity in the 1966 Eli Lilly study in another rat
strain (Sprague-Dawley rats, up to 2000 ppm in the diet for
2 years). Trifluralin did not appear to be oncogenic in the
1978 NCI study (Osborne Mendel rats, up to 6500 ppm in the
diet for 78 weeks), although this study is inconclusive
with regard to urinary tract tumors because too few dosed
animals were examined for these tumors. Trifluralin was
not oncogenic in the 1980 Lilly mouse study. In addition,
Industrie Prodotti Chemici has submitted both rat and mouse
oncogenicity studies, which have not yet been fully reviewed,
but indicate in the executive summaries that no compound related
oncogenic effects were observed. The Agency presently has
no reason to question the validity of these studies.
There was also no indication that the age of onset for
transitional cell renal tumors was reduced in dosed versus
control animals. The 1980 Lilly rat study did not incorporate
interim or serial sacrifices into its protocol for demonstrating
this specific response. However, the evidence examined from
the animals that were sacrificed as moribund or that died
prior to term did not demonstrate a relation between dosing
and age of onset for these tumors. Furthermore, survival
was unaffected by treatment since the majority of the tumors
were not discovered until terminal sacrifice.
Moreover, there was no evidence of mutagenicity in rat
dominant lethal, L5178Y mouse lymphoma, Ames Salmonella
typhimurium, Saccharomcyces cerevisciae, DNA repair assays,
or SCE using the Chinese hamster cell.
-------
Trifluralin arguably could satisfy the "sufficient
evidence" criteron on the basis of an increase in an
unusual "site or type of tumor." However, for the reasons
discussed below, the Agency does not believe this criterion
has been met.
The 1980 Lilly Fischer 344 rat study demonstrated
a statistically significant increase in tumors of transitional
cells of the renal pelvis of the kidney in males. The incidence
of these tumors in the 1980 study was 0% (control), 3.3%
(low dose), 5.1% (mid dose), and 10% (high dose). The high
dose incidence of 10% is for combined benign and malignant
tumors.
No malignant tumors at this site were observed in historical
control data from this strain. However, historical control
data show that male rats of this strain sometimes are afflicted
with benign tumors at the same site. Data* from control
animals in 24 studies conducted by Lilly using the Fischer
344 rat showed that although no carcinomas were observed at
that site, one male rat each of 30, 30, and 29 control male
rats was found to have a nonmalignant adenoma of the .renal
pelvis of the kidney. The 1984 Proposed Guidelines state
that "benign and malignant tumors will be combined unless
the benign tumors are not considered to have the potential
to progress to the associated malignancies of the same morphological
type." Since EPA considered that the benign tumors observed
in the historical controls could progress to malignant tumors
of the same morphological type, EPA considered the benign
tumors in the historical controls (range: 0% - 3.45%) when
determining whether the tumors seen in the male rats in the
1980 Lilly study were "unusual," and therefore concluded
that such tumors are not "unusual" or "rare."
The results of the various trifluralin studies did not
satisfy the other criteria for "sufficient evidence" of
carcinogenicity from animal evidence; that is, an increased
incidence of malignant tumors (or combined malignant and benign
tumors) — (a) in multiple species or strains, (b) in multiple
experiments, or (c) to an unusual degree with regard to age at
onset.
The 1984 Proposed Guidelines are somewhat ambiguous
regarding the categorization of a chemical where studies
present the pattern of results shown by trifluralin. However,
EPA has determined that the arguments favoring a "limited
evidence" categorization outweigh those favoring a "sufficient
evidence" categorization. Accordingly, EPA concludes that
trifluralin is a Category C (possible human) carcinogen.
20
-------
Dietary Risk
The oncogenic evidence is discussed above. The dietary
risk associated with exposure to trifluralin was calculated
in the PD4 issued in July 1982 (47 FR 33777). The dietary
risk has not changed on the basis of the Registration Standard
assessment of the oncogenicity data. Therefore, this section
summarizes the Agency's 1982 findings with regard to oncogenic
risk from dietary exposure to trifluralin and its N-nitrosamine
contaminants. A more detailed discussion of the risk estimates
may be found in Part II, Section C.2 of the PD4.
The total dietary risk from exposure to trifluralin is
5.3 x 10~7 assuming an average daily intake of 1.5 kilograms
of food a day for the average 65 kilogram person (based on
Oi* = 7.7 x 10"-*). This estimate represents the combined
risk of trifluralin itself and its N-nitrosamine contaminants.
The N-nitrosamine contribution to the dietary risk is considered
to be insignificant because its comprises such a minute
fraction of the end-use product.
Dietary exposure to trifluralin was calculated based on
the percentage of the crop acreage treated, actual trifluralin
residue data, food factors, and estimated trifluralin to
nitrosamine ratios.* The actual residue data available to the
Agency demonstrated that all reported residues of trifluralin were
either at or below the limit of detection (0.01 ppm). The reported
residues were approximately one-fifth of the established tolerances,
Assuming these data are generally representative of treated
crops, the Agency assigned a value of 0.01 ppm trifluralin
to all food commodities in which no detectable residues of
>0.01 ppm were reported. It is reasonable to assume that actual
residues of trifluralin are at or below this level.
*These ratios were calculated on the basis of a trifluralin
emulsifiable concentrate product which contains 44.5 percent
t-rifluralin or 445,000 ppm. Assuming that the NDPA and other
nitrosamines were individually present at levels of 0.10 ppm
and 0.02 ppm respectively, the ratio of trifluralin to NDPA
would be 4,450,000:1 (0.10 ppm) and to other nitrosamines,
22,250,000:1 (0.02 ppm).
-------
Worker Exposure and Risk
The oncogenic risk to mixers, loaders and applicators
of trifluralin via inhalation and dermal exposure was estimated
in the PD4 (July 1982) and no data have been received
since then to alter these calculations. The total risk to
commercial applicators from exposure to trifluralin was estimated
to be 2.0 x 10~7 based on the assumptions that a person
works an average of 40 years out of a lifetime of 70, an
average body weight of 65 kilograms, and a total exposure
of 1082.7 micrograms/year for all crops (based on QI* =
7.7 x 10-3).
In calculating these risks the Agency assumed a breathing
rate of 1.8 cubic meters per hour which closely approximates
the air intake for the type of work done by mixers, loaders,
applicators and field workers. Since there were no data
available on the dermal absorption rates of trifluralin, the
Agency estimated the extent of this exposure on the
basis of trifluralin's physical and chemical properties.
Trifluralin is a solid material having a melting point of
48.5 to 49.0°C and is essentially insoluble in water, but is
soluble in acetone, ethanol and xylene. In order to penetrate
skin to any appreciable amount, a solid must be soluble in
both water and organic solvents. Trifluralin would therefore
have a maximum absorption of no more than 1 percent as an
upper limit. When a trifluralin emulsifiable concentrate is
added to water for application, a microcrystalline suspension of
the solid is formed and dermal absorption would also not be expected
to be above 1 percent. This estimate applies only to applicators.
The Agency assumed that mixers and loaders wear suitable
protective clothing so that dermal exposure would not normally
be expected.
The Agency also calculated the reentry' risk of exposure
to trifluralin in the air and in the soil and determined that the
risk to field workers would be in the 10~9 range for six major
crop uses, including soybeans, cotton, and tomatoes. This
oncogenic risk estimate was calculated assuming that after a
single application of 1 Ib. active ingredient/acre a field
worker could experience 10 separate exposures annually.
That is, ten tasks were identified which could result in
exposure; the exposure was then estimated for each task.
The Agency estimated that a field worker could be exposed to
a total of 66.34 micrograms/year via inhalation and dermal
exposure to trifluralin vapor, and dermal exposure to treated
soil. The Agency therefore concluded that the risk to fieldworkers
from reentry would be expected to be quite low, particularly
since trifluralin is typically incorporated into the soil
after application. A detailed explanation of the Agency's
risk assessment can be found in Part II, Section C.3&4 of
the PD4.
22
-------
Tolerance Reassessment
The following tolerances have been established for residues
of trifluralin in raw agricultural commodities (40 CFR 180.207):
,Commodity Tolerance (ppm)
Alfalfa, hay ' 0.2
Asparagus 0.05
Barley, fodder 0.05
Barley, forage 0.05
Barley, hay 0.05
Barley, straw 0.05
Carrots 1.0
Citrus fruits 0.05
Corn, grain (excluding popcorn) 0.05
Corn, grain (excluding popcorn), forage 0.05
Corn, grain (excluding popcorn), fodder 0.05
Cottonseed 0.05
Cucurbits 0.05
Flax, seed 0.05
Flax, straw 0.05
Grain, crops (except fresh corn 0.05
and rice grain)
Grapes 0.05
Hops 0.05
Legumes, forage 0.05
Mung bean sprouts 2.0
Nuts 0.05
Peanut, hulls 0.1
Peanuts 0.05
Peppermint, hay 0.05
Rape, seed 0.05
Rape, straw . 0.05
Safflower seed 0.05
Sorghum, fodder 0.05
Sorghum, forage 0.05
Spearmint, hay 0.05
Stone fruits 0.05
Sugarcane 0.05
Sunflower seed • 0.05
Upland Cress 0.05
Vegetables, fruiting 0.05
Vegetables, leafy 0.05
Vegetables, root (excluding carrots) 0.05
Vegetables, seed and pod 0.05
Wheat, grain 0.05
Wheat, straw 0.05
23
-------
The following tolerances have been established for
trifluralin in processed foods (21 CFR 194.440):
Food Tolerance (ppm)
Peppermint oil 2
Spearmint oil 2
In addition, the following international tolerances have been
established for trifluralin:
Canadian tolerances of 0.1 ppm have been established for
residues of trifluralin in or on barley grain, beans (snap),
cole crops, flax, herbs, mustard seed", peas, peppers, rape seed,
soybeans, sunflower, tomatoes, and wheat.
Mexican tolerances of 0.05 ppm have been established for
residues of trifluralin in or on asparagus, broccoli, cabbage,
chili pepper, citrus fruits, corn forage, cottonseed, peanuts,
safflower seed, sugarcane, tree nuts and wheat. A Mexican
tolerance has also been established at 0.2 ppm for residues
of trifluralin per se in or on alfalfa hay.
No Codex Alimentarius Commission Maximum Residue Limits
have been established for residues of trifluralin.
The available data are insufficient to fully reassess the
established tolerances for residues of trifluralin. The
metabolism of trifluralin in plants and animals is not adequately
understood. Radiolabeled studies conducted to characterize
residues of trifluralin and its metabolites in carrot roots
provide an adequate description of the metabolism of trifluralin
in root crops only. Radiolabeled studies to assess the
uptake and translocation of trifluralin on other crops were
not adequate to depict metabolism in the foliage of crops
treated via soil application and on crops, such as corn,
sorghum, and sugar beets, which may be treated via direct
foliar application. At present, trifluralin per se is considered
to be the sole residue of concern in plants. However, trifluralin
has twelve known metabolites which must be sufficiently quantified
Presently, no tolerances exist for residues of trifluralin
in animal products because residues were not characterized in
tissues and milk of ruminants and no poultry data were submitted.
24
-------
Adequate methods are available to detect trifluralin
residues in or on plant commodities for data collection and
enforcement procedures, including a method to detect trifluralin
in the presence of interfering pesticides.
There are adequate data to ascertain that residues of
trifluralin are stable on frozen plant products for
up to ten months and on plant products stored in the dark
in polyethylene bags at room temperature for up to 121 days.
However, the Agency is lacking data depicting the storage
intervals and conditions of storage of samples used to support
all established tolerances for residues of trifluralin, and
data depicting the percent decline in residues at the times
and under the conditions specified.
Sufficient residue data are available only to ascertain
the adequacy of the established tolerances for residues of
trifluralin in or on the following commodities: carrots,
fruiting vegetables, citrus fruits, grapes, (tree) nuts,
wheat grain, barley forage, asparagus, flax seed, cottonseed,
hops, peanuts and peanut hulls, peppermint and spearmint
hay, rape seed, safflower seed, sugarcane, and sunflower
seed. (Depending upon the results of required plant
metabolism studies, this conclusion may change, with the
exception of root crops as discussed earlier in this section.)
Data on the magnitude and levels of residues present in
various agricultural commodities are either unavailable or
insufficient to assess the adequacy of existing tolerances
remaining or to establish new tolerances for crops now
included in obsolete crop groups. There is also not sufficient
data to determine whether residues concentrate when several
of the commodities are processed.
The Acceptable Daily Intake (ADI) and the Maximum Permissible
Intake (MPI) are two ways of expressing the amount of a substance
that the Agency believes, on the basis of the results of data
from animal studies and the application of "safety" or
"uncertainty" factors, may safely be ingested by humans without.
risk of non-oncogenic adverse health effects. The ADI is
expressed in terms of milligrams (mg) of the substance per
kilogram (kg) of body weight per day (mg/kg/day). The MPI,
a related figure, is obtained by assuming a human body weight
of 60 kg, and is expressed in terms of mg of substance per day
(mg/day). The Agency has calculated a Provisional ADI (PADI)
of 0.01 mg/kg/day for trifluralin on the basis of missing data.
The MPI for trifluralin is 0.6 mg/day.
25
-------
The PADI for trifluralin currently is based on the results from
a 3-year dog feeding study, from which the Agency concluded that
the no-observed-effect level (NOEL) was seen at 400 ppm of the
substance in the animals' diet, or 10 mg/kg of animal body weight/day.
400 ppm in the diet was the lowest dose administered; compound-related
increases in emesis and liver weight were observed at the mid-
and high-dose levels. The PADI was derived by use of a
safety factor of 1000 (to account for possible intra- and
inter-species differences and to allow for the incompleteness of
the chronic toxicity base in the rat). The NOEL from the dog study,
10/mg/kg/day, divided by this 1000-fold factor, yields a
human PADI of 0.01 mg/kg/day. The MPI for a 60-kg human thus
is 0.6 mg/day.
The theoretical maximum residue contribution (TMRC) is the
theoretically maximum amount of residues of a pesticide that might
be present based in the human diet, based on assumptions the Agency
makes about the average human daily intake of foods containing
residues at the level of the established tolerances. The
established tolerances for trifluralin have a theoretical
maximum residue contribution (TMRC) of 0.0429 mg/day in a
1.5 kg diet. The percentage of the PADI utilized is 7%. The
Agency will recalculate the ADI for trifluralin when additional
data are available to establish a NOEL for nephrotoxic effects
observed in the rat.
26
-------
PART IV. REGULATORY POSITION AND RATIONALE
A. REGULATORY POSITIONS AND RATIONALES
Based on review and evaluation of most available data* and
other relevant information on trifluralin, the Agency has
made the following determinations. Where labeling requirements
are imposed, specific language is set forth in Part IV, Section D.
1. If any of the risk criteria in 40 CFR Part 154.7 has been
met or exceeded, a special review of the chemical is conducted.
Trifluralin does not meet any of the criteria, and therefore is
not being placed into the special review process at this. time.
Rationale; Although trifluralin is oncogenic to male and female
rats, EPA does not believe that trifluralin meets the criterion
in 40 CFR 154.7(b)(2) for starting a special review. EPA's
special review rules provide that the Administrator may conduct
a special review if a pesticide use "may pose a risk of inducing in
humans an oncogenic...effect, which is of concern in terms of
either the degree of risk to individual humans or the number of
humans at some risk..." (50 FR 49016, November 27, 1985). EPA
concludes that the risk of oncogenic effects is not of sufficient
concern to warrant a special review of trifluralin. The
Registration Standard review of the data on trifluralin reaffirms
'the Agency's estimate of the risks in the earlier Special Review
review of the chemical. (The results of this review are
discussed in Part II, C. of the PD4.)
2. The Agency will continue to require that registrants of
products containing trifluralin:
(a) maintain total N-nitrosamine content in technical
trifluralin at levels no greater than 0.5 ppm;
(b) identify and quantify all N-nitrosamine contaminants
likely to appear in technical manufacturing use products;
(c) advise the Agency as to the quality control procedures
used to assure that the level of total N-nitrosamine
contamination does not exceed that declared on the
the Confidential Statement of Formula;
(d) maintain total N-nitrosamine contamination in
formulated products at levels no greater than a number
to be calculated as follows: 0.5 ppm total N-nitrosamine
contamination allowed in technical trifluralin x X%
technical trifluralin in the end-use product x 2 to allow
for possible generation of nitrosamines during the
formulation process.
*See the addendum to the Bibliography for a partial list of data
on trifluralin not yet reviewed.
27
-------
Rationale; Many N-nitroso compounds are known to be carcinogenic
and may pose a risk to human health. Therefore, it is necessary
to assure that exposure to these compounds which contaminate
pesticides is kept to a minimum. In June 1980, the Agency
published a proposed policy concerning regulation of
pesticides contaminated with N-nitroso compounds (45 FR 42854).
This policy indicated that contamination with carcinogenic
N-nitroso compounds at levels exceeding 1 ppm (with an individual
life-time risk to farmers, applicators, and other exposed
populations exceeding 1 x 10~°) would be cause for concern
and possible regulatory investigation or action. The N-nitroso
contamination limits imposed on trifluralin registrants are consistent
with this policy.
3. The Agency will not require restricted use classification for
trifluralin end-use products.
Rationale; Trifluralin is not acutely toxic (toxicity category III)
when tested via the dermal, inhalation, oral and ocular routes
in rats and rabbits. Some liquid formulations containing
trifluralin have been assigned toxicity category II on the
basis of more acutely 'toxic inert ingredients. Trifluralin
therefore does not meet the acute toxicity criteria (40 CFR
162.11) for a restricted use classification.
4. The Agency is not requiring reentry intervals or
unique human hazard precautionary statements for currently
registered trifluralin products.
Rationale; As indicated above, the acute toxicity of trifluralin
is low (Category III) for the vast majority of products.
Additionally, trifluralin is normally incorporated into the
soil within 24 hours after application and therefore exposure
and resultant risks to field workers are expected to be
quite low. The only remarkable acute toxicity finding on
trifluralin is that it is a skin sensitizer; that is, it
may cause allergic reactions in certain susceptible people.
5. The Agency is requiring submission of general metabolism
and dermal penetration studies.
Rationale; General metabolism and dermal penetration studies
are normally required by 40 CFR Part 158.135 for products
with trifluralin1s use patterns.
28
-------
6. The following data are required to fully assess the environmental
fate of trifluralin: photodegration studies in water and on
soil; aerobic and anaerobic soil and aquatic metabolism
studies; leaching and adsorption/desorption studies; volatility
studies; soil, aquatic, and long-term field dissipation
studies; and accumulation studies on rotational and irrigated
crops, fish, and other non-target aquatic organisms.
Rationale; Except for the hydrolysis data, all the environmental
fate data do not meet the guidelines standards for acceptable
testing. These data are normally required under 40 CFR Part
158.130 and are necessary to assess the environmental fate
and transport and the potential exposure to trifluralin.
7. The Agency is not requiring monitoring studies to assess
the potential for trifluralin to contaminate ground water.
Rationale; Five leaching and adsorption/desorption studies
were reviewed and classified as only supplementary because
they were not conducted in accordance with current testing
guidelines. However, these data do not suggest that trifluralin
is a potential groundwater contaminant. Trifluralin is in a
class of immobile chemicals which have little potential for
leaching to ground water.
8. The Agency is requiring registrants to conduct multi-year/
multi-site fish residue monitoring studies to determine
the extent to which fish accumulate residues of trifluralin
throughout the areas of major usage. (Refer to Table A for
a full description of the data required.)
Rationale; Available data indicate that trifluralin, when used
on soybeans under normal conditions, is transported to aquatic
environments via soil run-off, is detected in pond sediment and can
accumulate to detectable levels in fish. Vertebral anomalies
(minor lesions) were observed in 0% to 25% of the fish removed
from the test pond and pathologically examined. These data suggest
that trifluralin may contribute to increased vertebral anomalies
in fish. The Agency requires additional data to determine
whether this may be a widespread problem.
29
-------
9. The Agency is requiring that all labels of end-use
products containing trifluralin registered for use on ditchbanks
bear irrigation water restrictions. (Refer to Part IV,
Section D for the wording of this statement.)
Rationale; Trifluralin is registered for use on ditchbanks
which may serve as a source of irrigation water for food or feed
crops. There is insufficient data on the bioaccumulation of
trifluralin in water on such sites. Restrictions are therefore
necessary to avoid impermissible residues in food or feed.
10. The Agency is requiring that trifluralin granular products
intended for use on turf bear precautionary language concerning
exposure of children and domestic animals. (Refer to Part IV,
Section D for the exact language. )
Rationale; The Agency is concerned that children and domestic
animals may inadvertantly come into contact with or consume
the granules before the treated area is properly irrigated
so the granules are dissolved and absorbed by the soil.
11. The Agency has determined that the use of trifluralin
on croplands poses a risk to certain endangered or threatened
plant and aquatic species. All manufacturing-use and
end-use products will therefore be required to bear appropriate
labeling precautions.
Rationale; Based on a consultation with the Office of
Endangered Species, the Agency has determined that
the use of trifluralin on corn, soybeans, cotton, sorghum,
and small grains could impact several Federally designated
endangered species. Appropriate precautionary labeling is
not however being required through this Registration Standard.
The Agency will soon issue a Pesticide Registration Notice
to implement endangered species labeling requirements for a
number of pesticides. That notice will contain the precise
label text required and the timeframes for inclusion on the label.
12. Available residue chemistry and toxicology data are insufficient
to permit the Agency to conduct a full tolerance reassessment.
Rationale; Data gaps exist for plant and animal metabolism,
storage stability, analytical methods, magnitude of residues
in several raw agricultural commodities and processed food and
feed items. Thus, upon receipt of the data required in Table
A, the Agency's conclusions with regard to the adequacy of
established tolerances are subject to change. Since the
data required for individual commodities are dependent on the
metabolism data, the metabolism data will be obtained and
reviewed prior to any required residue data.
30
-------
13. The Agency is requiring additional data to quantify and identify
the nature of residues in plants, poultry (including eggs),
and ruminants (including milk).
Rationale; The metabolism of trifluralin in both plants and
animals is not adequately understood. Available information
indicates that approximately 80 percent of the residue present in
plants is trifluralin per se. However, trifluralin has several
known metabolites which require identification and quantification
in plants. Tolerances may, upon receipt of the required data,
be revised to include both the parent compound and metabolites
which are of toxicological concern.
There are presently no tolerances for trifluralin
in meat and poultry and their by-products. Since ruminants
and chickens may reasonably be expected to consume feeds from
crops treated with trifluralin, additional data are required to
characterize residues and to determine the need for tolerances
in animal products.
14. The Agency is not requiring additional residue data on
the following raw agricultural commodities: carrots, turnips,
fruiting vegetables, citrus fruits, grapes, (tree) nuts,
wheat grain, barley forage, asparagus, flax seed, cottonseed,
hops, okra, peanuts and peanut hulls, peppermint and spearmint
hay, rape seed, safflower seed, sugarcane, and sunflower
seed.
Rationale: The Agency has determined, that the available
residue data adequately support the established tolerances
for these raw agricultural commodities. However, depending
upon the results of plant metabolism studies, these tolerances
(with the exception of root crops for which metabolism has
been characterized) may be revised to reflect expression of
both trifluralin and metabolites of toxicological concern.
15. The Agency is requiring additional residue data on the
following raw agricultural commodities: corn grain, sorghum grain,
corn forage and fodder, alfalfa hay, sorghum forage, flax straw,
and peppermint and spearmint oil.
Rationale; A review of the available data indicates that the Agency
does not have sufficient residue data to support the established
tolerances for trifluralin on the above commodities. (Refer to
Table A for a description of the data being required.)
31
-------
16. The Agency is requiring processing data for the following
raw agricultural commodities: potatoes, sugar beets, soybeans, citrus
fruits, sorghum, barley, corn and wheat grain, alfalfa hay,
flax seed, cottonseed, peanuts, spent peppermint and spearmint hay,
sugarcane and sunflower seed.
Rationale: There are no data available to determine whether
residues of trifluralin concentrate when these commodities are
processed into food or feed items.
17. (a) The Agency is deleting the following crop group
tolerances established for trifluralin: root crops, leafy
vegetables, seed and pod vegetables, forage legumes, cucurbits,
stone fruits, and grain crops.
(b) The Agency will establish the following crop group tolerances:
leaves of root and tuber vegetables, Brassica leafy vegetables,
legume vegetables (succulent and dried), foliage of legume
vegetables, fruiting vegetables, and tree nuts.
Rationale: (a) These crop groups were established prior to
June 1983 when the Agency's crop grouping scheme was substantially
revised, and they are therefore now obsolete. They will
be replaced by new crop groups set forth in 40 CRF 180.34
if sufficient data on representative crops are available.
(b) Available residue data on existing members of the groups
are adequate to support such group tolerances, and the uses
and tolerances are significantly similar as required by 40
CFR 180.34(f). (Refer to Table A for a list of the commodities
included in the groups.)
-------
18. The Agency has determined that the following crop group
tolerances cannot be established: root and tuber vegetables,
bulb vegetables, leafy vegetables (except Brassica), cucurbits,
stone fruits, small fruits and berries, cereal grains, forage,
fodder, and straw of cereal grains and non-grass animal feeds.
Rationale; The reasons that group tolerances are not appropriate
are because residue data are not available for designated
representative crops or use patterns are not sufficiently similar.
Separate tolerances will be established for all the •commodities
which would be subject to these group tolerances. These
commodities are listed in Table A.
19. The Agency has determined that tolerance proposals and
supporting residue data are needed for the following raw
agricultural commodities: corn silage, sorghum hay and silage,
wheat forage and hay, alfalfa forage, cotton forage, peanut
vines and hay, sugarcane forage, sunflower forage, and turnip roots
Rationale; There is either no data or insufficient data to
characterize residues on these commodities on which residue
can be reasonably expected to occur and transfer to animals in
feed items. In addition, for peanut vines and hay, and
cotton, sugarcane, and sunflower forage, registrants may
place appropriate grazing/feeding restrictions on their
labels as an alternative to generating the data. Each registrant
will have six months to notify the Agency of which alternative
is selected. (Refer to Table A for a detailed description of
the residue data required.)
20. The Agency has determined that the tolerances for barley
and wheat straw (0.05 ppm) should be increased to 0.1 ppm.
Rationale; Available data demonstrate that residues occurring
in these commodities exceeded or would exceed the existing
tolerance taking low recovery rates into account. The dietary risk
of increasing these tolerances is likely to be quite low since
the contribution to the TMRC would not be significant. This
decision is, however, dependent on the studies to determine
how animals metabolize trifluralin consumed from treated feed
items.
33
-------
21. The Agency will not establish any new food/feed additive
regulations pursuant to section 409 of the Federal Food,
Drug, and Cosmetic Act (FFDCA) and is deferring action on
previously established food/feed additive regulations.
Rationale; The Delaney Clause in section 409 of the FFDCA
bars the establishment of food additive regulations for
substances which induce cancer in man or test animals,
with exceptions which may not apply here. The Agency is
currently developing a position relative to the Delaney
Clause and FIFRA. Once this policy has been established,
the Agency will determine what action is required in relation
to pesticides which have induced positive oncogenic responses
in chronic animal studies.
22. While the data gaps are being filled, currently registered
manufacturing-use products (MPs) and end-use products (EPs)
containing trifluralin as the sole active ingredient may be sold,
distributed, formulated and used in the United States, subject
to the terms and conditions specified in this Registration
Standard. Registrants -must provide or agree to develop additional
data, as specified in Table A of the Appendices, in order
to maintain existing registrations.
The Agency will issue registrations for substantially
similar products. However, new uses will be approved only on
a case-by-case basis after considering the effects on the
theoretical maximum residue contribution (TMRC) and the
maximum permissible intake (MPI), and the oncogenic risks.
Rationale: While the currently available data are not
adequate to support the registration of any registered trifluralin
product unconditionally under FIFRA sec. 3(c)(5), the available
data do support the conditional registration of all of the
currently registered products. Under the FIFRA, the Agency
does not normally cancel or withhold registration simply
because data are missing or inadequate [see FIFRA sections
3(c)(2)(B) and (3)(c)(7)]. Issuance of this Standard provides
a mechanism for identifying data needs. These data will be
reviewed and evaluated. The Agency will then determine
whether additional regulatory changes are necessary.
34
-------
B. CRITERIA FOR REGISTRATION
To be covered under this Standard, manufacturing use products
must contain trifluralin as the sole active ingredient, bear
required labeling, and conform to the product composition, acute
toxicity limits, and use pattern requirements listed in
Appendix B, EPA Index to Pesticide Chemicals.
C. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Standard
To be registered or reregistered under this Standard, manu-
facturing use products must contain trifluralin as the sole
active ingredient. Each manufacturing use formularion proposed
for registration must be fully described with an appropriate
certification of limits, stating maximum and minimum amounts of the
active ingredient and inert ingredients which are present in products,
as wll as impurities found at greater than 0.1%.
2. Acute Toxicity Limits
The Agency will consider registration of technical grade and
manufacturing-^use products containing trifluralin, provided that
the product labeling bears appropriate precautionary statements
for the acute toxicity category in which each product is placed,
as required by 40 CFR 162.10.
3. Use Patterns
To be registered under the standard, technical grade or
manufacturing-use products containing trifluralin may be labeled
for formulation into end-use products registered for the uses
listed in Appendix B, EPA Index to Pesticide Chemicals — Trifluralin.
This index lists all registered uses, as well as the approved
maximum application rates and frequencies.
35
-------
D. LABELING AND PACKAGING REQUIREMENTS
All labeling changes required by this Standard must appear
on all manufacturing-use products and end-use products released
for shipment by the registrant within 1 year of issuance of this
Standard. Within 2 years after issuance of this standard, all
labeling requirements must appear on all products distributed, sold,
offered for sale, held for sale, shipped, delivered for shipment, or
received (and having been so received) delivered or offered to
be delivered by any person.
The following information must appear on the labeling:
1. All Products. All products must bear appropriate
labeling as specified in 40 CFR 162.10. Specific
information on label requirements are contained in
the Appendix II, Labeling Appendices.
a. Ingredient Statement. The ingredient statement must
list the active ingredient as:
Trifluralin: alpha,alpha,alpha-trifluoro-2,6-
dinitro-N,N-dipropyl-p-toluidine... %
b. Disposal Statements. Because trifluralin has not
been designated as an acute or toxic hazardous waste
under the Resource Conservation and Recovery Act (RCRA),
the following is the appropriate pesticide disposal
statement for trifluralin products:
"Wastes resulting from the use of this product
may be disposed of on site or at an approved
waste disposal facility."
The labels of all products must bear the appropriate
container disposal statement (Labeling Appendices).
2. Technical Grade/Manufacturing-Use Products
a. Use Pattern Statements. Labeling for all technical grade
and manufacturing-use trifluralin products must state
that they are intended for formulation into end-use
herbicide products registered for one or more of the
uses set forth in the EPA Index to Pesticide Chemicals -
Trifluralin, Appendix B. However, no use may be
included on such labeling if the registrant fails to
agree to comply with the data requirements for that use
pattern as listed in Table A and/or Table B, Appendix I,
as appropriate.
-------
b. Precautionary Statements. Labels for technical grade
and manufacturing-use pesticide products must bear
statements reflecting the compound's acute human
toxicity, as specified in 40 CFR 162-.10 (Labeling Appendices),
and statements pertaining to environmental hazard. In
addition, all manufacturing-use products must contain
the following environmental precautionary statement:
"Do not discharge effluent containing this product into
lakes, streams, ponds, estuaries, oceans, or public
water unless this product is specifically identified
and addressed in an NPDES* permit. Do not discharge
effluent containing the product into sewer systems
without previously notifying the sewage treatment
plant authority. For guidance contact your State
Water Board or Regional Office of the EPA."
3. Statements for End-Use Products.
a. The following environmental precautionary statement must
appear on the label of each product registered for any
outdoor use:
"This pesticide is toxic to fish. Do not apply
directly to water or wetlands (swamps, bogs, or
marshes). Drift or runoff from treatment areas
may be hazardous to aquatic organisms in neighboring
aquatic sites. Do not contaminate water by cleaning
of equipment or disposal of waste."
b. The following restrictions must appear on the label of each
end-use product labeled for use on ditchbanks:
"Do not use irrigation water on food or feed crops within
18 months after application of trifluralin to ditchbanks
unless it is determined that the water is free of
trifluralin residues."
*National Pollution Discharge Elimination System
37
-------
The label of each end-use product registered for weed
control on lawns must bear the following precautionary
statement:
"Do not allow children or pets on lawn until 1/2"
of water has been applied to lawn and the water has
dried (or, if wet conditions persist, until 24
hours have passed)."
38
-------
V. PRODUCTS SUBJECT TO THIS STANDARD
All products containing the pesticide identified in
Section II.A. are subject to certain requirements for data
submission or changes in composition, labeling or packaging
of the product. The applicable requirements depend on whether
the product is a manufacturing or end use product and whether
the pesticide is the sole active ingredient or one of multiple
active ingredients.
Products are subject to this Registration Standard as
follows:
A. Manufacturing use products containing this pesticide as
the sole active ingredient are subject to: 1) The restrictions
upon use, composition, or packaging listed in Section IV;
2) The data requirements listed in Tables A and B; 3) The
labeling requirements specified for manufacturing-use products
in Section IV; 4) Administrative requirements (application
forms, Confidential Statement of Formula, data compensation
provisions) associated with reregistration.1
B. End-use products containing this pesticide are subject to:
1) The labeling requirements specified for end-use products
in Section IV; 2) If not eligible for the formulator's exemption,
the data requirements listed in Table A.^
1 Data requirements are listed in the Tables in Appendix I
'of this Registration Standard. The Guide to Tables in that
lAppendix explains how to read the Tables. Table A lists
generic data requirements applicable to all products containing
the pesticide subject to this Registration Standard. Table
B lists product-specific data applicable to manufacturing-use
products. The data in Tables A and B need not be submitted
by a producer who is eligible for the formulator's exemption.
2 If you purchase from another producer and use as the
source of your active ingredient only EPA-registered products,
you are eligible for the formulator's exemption for generic
data concerning that active ingredient (Table A) and product-
specific data for the registered manufacturing use product
you purchase (Table B). Two circumstances nullify this
exemption: 1) If you change sources of active ingredient to
an unregistered product, formulate your own active ingredient,
or acquire your active ingredient from a firm with ownership
in common with yours, you individually lose the exemption
and become subject to the data requirements in Table A.
2) If no producer subject to the generic data requirements
in Table A agrees to submit the required data, all end use
producers lose the exemption, and become subject to those
data requirements.
39
-------
VI. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
This portion of the Registration Standard is a notice
issued under the authority of FIFRA sec. 3(c)(2)(B). It
refers to the data listed in Table A, which are required to
be submitted by registrants to maintain in effect the regis-
tration of products containing this active ingredient.^
A. What are generic data?
Generic data pertain to the properties or effects of a
particular active, ingredient. Such data are relevant to an
evaluation of all products containing that active ingredient
regardless of whether the product contains other ingredients.
(unless the product bears labeling that would make the data
requirement inapplicable).
Generic data may also be data on a "typical formulation"
of a product. "Typical formulation" testing is often required
for ecological effects studies and applies to all products
having that formulation type. These are classed as generic
data, and are contained in Table A.
B. Who must submit generic data?
All current registrants are responsible for submitting
generic data in response to a data request under FIFRA sec.
3(c)(2)(B) (DCI Notice). EPA has decided, however, not to
require a registrant who qualifies for the formulator's
exemption (FIFRA sec. 3(c)(2)(D) and § 152.85) to submit
generic data in response to a DCI notice if the registrant
who supplies the active ingredient in his product is complying
with the data request.
If you are not now eligible for a formulator's exemption,
you may qualify for one if you change your source of supply
to a registered source that does not share ownership in
common with your firm. If you choose to change sources of
supply, the Confidential Statement of Formula must identify
the new source(s) and you must submit a Formulator's Exemption
Statement form.
If you apply for a new registration for products containing
this active ingredient after the issuance of this Registration
Standard, you will be required to submit or cite generic
data relevant to the uses of your product if, at the time
3 Registrations granted after issuance of this Standard
will be conditioned upon submission or citation of the data
listed in this Registration Standard.
40
-------
the application is submitted, the data have been submitted
to the Agency by current registrants. If the required data
have not yet been submitted, any new registration will be
conditioned upon the new registrant's submission or citation
of the required data not later than the date upon which
current registrants of similar products are required to provide
such data. See FIFRA sec. 3(c)(7)(A). If you thereafter fail
to comply with the condition of that registration to provide
data, the registration may be cancelled (FIFRA sec. 6(e)).
C. What generic data must be submitted?
You may determine which generic data you must submit by
consulting Table A. That table lists the generic data needed
to evaluate current uses of all products containing this
active ingredient, the uses for which such data are required,
and the dates by which the data must be submitted to the
Agency.
D. How to comply with PCI requirements.
Within 90 days of your receipt of this Registration
Standard, you must submit to EPA a completed copy of the form
entitled "FIFRA Section 3(c)(2)(B) Summary Sheet" (EPA Form
8580-1, enclosed) for each of your products. On that form
you must state which of the following six methods you will
use to comply with the DCI requirements:
1. You will submit the data, and either —
(a) Submit the existing data that you believe will
satisfy the data requirements, or
(b) State that you will secure the data or have
made a contract to have any necessary studies completed
within the'applicable time period.
2. You have entered into an agreement with one or more
, registrants to jointly develop (or share in the cost of
developing) the data, but will not be submitting the data
yourself. If you use this method, you must state who will
submit the data on which you will rely. You must also provide
EPA with documentary evidence that an agreement has been
formed which allows you to rely upon the data to be submitted.
Such evidence may be: (1) your letter offering to join in
an agreement and the other registrant's acceptance of your
offer, (2) a written statement by the parties that an agreement
exists, or (3) a written statement by the person who will be
submitting the data that you may rely upon its submission.
The Agency will also require adequate assurance that the
person whom you state will provide the data is taking appropriate
steps to secure it. The agreement to produce the data need
not specify all of the terms of the final arrangement between
the parties or a mechanism to resolve the terms.
41
-------
3. You have attempted to enter into an agreement to
jointly develop data, but no other registrant has accepted
your offer. You request that EPA not suspend your registration
for non-compliance with the PCI. EPA has determined that,
as a general policy, it will not suspend the registration of
a product when the registrant has in good faith sought and
continues to seek to enter into a data development/cost
sharing program, but the other registrants developing the
data have refused to accept its offer. [If your offer is
accepted, you may qualify for Option 2 above by entering
into an agreement to supply the data.]
In order to qualify for this method, you must:
1. File with EPA a completed "Certification of Attempt
to Enter into an Agreement with other Registrants for Develop-
ment of Data" (EPA Form 8580-6, enclosed).
2. Provide us with a copy of your offer to the other
registrant and proof of the other registrant's receipt of your
offer (such as a certified mail receipt). Your offer must,
at a minimum, contain the following language or its equivalent:
[Your company name] offers to share in the burden of
producing the data required pursuant to FIFRA sec.
3(c)(2)(B) in the [name of active ingredient] Registration
Standard upon terms to be agreed or failing agreement
to be bound by binding arbitration as provided by FIFRA
section 3(c)(2)(B)(iii).
The remainder of your offer may. not in any way attempt to
limit this commitment. If the other registrant to whom your
offer is made does not accept your offer, and if the other
registrant informs us on a DCI Summary Sheet that he will
develop and submit the data required under the DCI, then you
may qualify for this option. In order for you to avoid
suspension under this method, you may not later withdraw or
limit your offer to share in the burden of developing the
data. In addition, the other registrant must fulfill its
commitment to develop and submit the data.
4. You request a waiver of the data requirement. If
you believe that a data requirement does not (or should not)
apply to your product or its uses, you must provide EPA with
a statement of the reasons why you believe this is so. Your
statement must address the specific composition or use factors
that lead you to believe that a requirement does not apply.
Since the Agency has carefully considered the composition and
uses of pesticide products in determining that a data require-
ment applies, EPA does not anticipate that many waivers will
be granted. A request for waiver does not extend the time-
frames for developing required data, and if your waiver
request is denied, your registration may be suspended if you
fail to submit the data.
42
-------
5. You request that EPA amend your registration by deleting
the uses for which the data are needed. You are not required
to submit data for uses which are no longer on your label.
6. You request voluntary cancellation of the registration
of your product(s) for which the data are needed.
E. Procedures for requesting a change in testing protocol.
If you will generate the required data and plan to use
test procedures which deviate from (or are not specified in)
either EPA's Pesticide Assessment Guidelines or the Reports
of Expert Groups to the Chemicals Group, Organization for
Economic Cooperation and Development (OECD) Chemicals Testing
Programme/ you must submit for EPA approval the protocols
you propose to use.
You should submit your protocols before beginning testing
and await EPA approval, because the Agency will not ordinarily
accept as sufficient studies using unapproved protocols.
A request for protocol approval will not extend the timeframe
.for submission of the data, nor will extensions generally be
given to conduct studies due to submittal of inappropriate
protocols.
F.' Procedures for requesting extensions of time.
If you think that you will need more time to generate
the data than is allowed by EPA's schedule, you may submit a
request for an extension of time. Any request for a time
extension which is made as an initial response to a section
3(c)(2)(B) request notice must be submitted in writing to
the P-roduct Manager listed at the end of this section and
must be made before the deadline for response. Once dates
have been committed to and EPA has accepted these commitments,
any subsequent requests for a time extension must be submitted
in writing to the Office of Compliance Monitoring.
EPA will view failure to request an extension before
the response deadline as a waiver of any future claim that
there was insufficient time to submit the data. While EPA
considers your request, you must strive to meet the deadline
for submitting the data.
The extension request should state the reasons why you
believe that an extension is necessary and the steps you
have taken to meet the testing deadline. Time extensions
normally will not be granted due to problems with laboratory
capacity or adequacy of funding, since the Agency believes
that with proper planning these can be overcome. Time extensions
may be considered when joint data development is planned,
43
-------
or when the Agency must approve a new or modified protocol
before the study can be begun.
A request for an extension does not automatically extend
the timeframe for submission of the data. If EPA denies
your request for a time extension and you do not submit the
data as requested, EPA may begin proceedings to suspend the
registrations of your products.
G. Existing stocks provision upon suspension or cancellation.
The Agency has determined that if a registration is
suspended for failure to respond to a DCI request under
FIFRA sec. 3(c)(2)(B), an existing stocks provision is not
consistent with the Act. Accordingly, the Agency does not
anticipate granting permission to sell or distribute existing
stocks of suspended product except in rare circumstances.
If you believe that your product will be suspended or cancelled
and that an existing stocks provision should be granted, you
have the burden of clearly demonstrating to EPA that granting
such permission would be consistent with the Act. The following
information must be included in any request for an existing
stocks provision:
1. Explanation of why an existing stocks provision is
necessary, including a statement of the quantity of
existing stocks and your estimate of the time required
for their sale or distribution; and
2. Demonstration that such a provision would be consis-
tent with the proyisipns of FIFRA.
44
-------
VII. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Under its DCI authority, EPA has determined that certain
product-specific data are required to maintain your registrations
in effect. Product-specific data are derived from testing
using a specific formulated product, and, unlike generic
data, generally support only the registration of that product.
All.such data must be submitted by the dates specified in
this Registration Standard.
If you have a manufacturing-use product, these data are
listed in Table B. As noted earlier, the Agency has decided
that it will not routinely require product-specific data for
end use products at this time.
In order to comply with the product specific data require-
ments, you must follow the same procedures as for generic data.
See Section VI.D, E, F, and G. You should note, however, that
product chemistry data are required for every product, and the
only acceptable responses are options VI.D.I. (submit data)
or VI.D.6.(cancellation of registration).
Failure to comply with the product-specific data require-
ments for your products will result in suspension of the
product's registration.
-------
VIII. REQUIREMENT FOR SUBMISSION OF REVISED LABELING
FIFRA requires each product to be labeled with accurate,
complete and sufficient instructions and precautions, reflecting
the Agency's assessment of the data supporting the product
and its uses. General labeling requirements are set out in
40 CFR 162.10 (see Appendix II - LABELING and SUMMARY). In
addition, labeling requirements specific to products containing
this pesticide are specified in Section IV.D of this Registra-
tion Standard. Applications submitted in response to this
notice must include draft labeling for Agency review.
If you fail to submit revised labeling as required,
which complies with 40 CFR 162.10 and the specific instructions
in Section IV.D., EPA may seek to cancel or suspend the
registration of your product under FIFRA sec. 6(b)(l).
46
-------
IX. INSTRUCTIONS FOR SUBMISSION
A. Manufacturing Use Products (MUPs) containing Trifluralin
as sole active ingredient.
1. Within 90 days from receipt of this document, you
must submit to the Product Manager in the Registration Division
for each product subject to this Registration Standard:
a. The "FIFRA Section 3(c)(2)(B) Summary Sheet" (EPA
Form 8580-1), with appropriate attachments.1*
b. Confidential Statement of Formula (EPA Form 3570-4).
cv Formulator's Exemption Statement (EPA Form ),
if applicable.
d. Evidence of compliance with data compensation
requirements of FIFRA sec. 3(c)(l)(D). Refer to 40 CFR
152.80-152.99.
2. Within 9 months from receipt of this document you
must submit to the Product Manager:
a. Two copies of any required product-specific data
(See Table B).
b. Five copies of draft labeling, including the
container label and any associated supplemental labeling.
Labeling should be either typewritten text on 8-1/2 x 11
inch paper or a mockup of the labeling suitable for
storage in 8-1/2 x 11 files. The draft label must indicate
the intended colors of the final label, clear indication
of the front panel of the label, and the intended type
sizes of the text.
4 If on the Summary Sheet, you commit to develop the data,
present arguments that a data requirement is not applicable
or should be waived, or submit protocols or modified protocols
for Agency review, you must submit a copy of the Summary
sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data
generated in response to this notice. This submission is in
addition to responding to the Product Manager, and should be
submitted to the Office of Compliance Monitoring at the
address given at the end of this section. (Actual studies
are not to be submitted to the Office of Compliance Monitoring.)
-------
3. Within the times set forth in Table A, you must
submit to the Registration Division all generic data, unless
you are eligible for the formulator's exemption. If for any
reason any test is delayed or aborted so that the schedule
cannot be met, immediately notify the Product Manager and
the Office of Compliance Monitoring of the problem, the
reasons for the problem, and your proposed course of action.
B. End Use Products containing Trifluralin alone or in combination
with Other Active Ingredients.
1. Within 90 days from receipt of this document, you
must submit to the Product Manager in the Registration Division:
a. FIFRA Section 3(c)(2)(B) Summary Sheet, with
appropriate attachments4 (EPA Form 8580-1), or the
Formulator's Exemption Statement (EPA Form ).
b. Confidential Statement of Formula (EPA Form 8570-4).
2. Within 9 months from receipt of this document you must
submit to the Product Manager:
a. Five copies of draft labeling, including the
container label and any associated supplemental labeling.
Labeling should be either typewritten text on 8-1/2 x 11
inch paper or a mockup of the labeling suitable for
storage in 8-1/2 x 11 files. The draft labeling must
indicate the intended colors of the final label, clear
indication of the front panel of the label, and the
intended type sizes of the text. End use product labeling
must comply specifically with the instructions in Section IV
(Regulatory Position and Rationale).
48
-------
D. Intrastate Products containing Trifluralin either
as sole active ingredient or in combination with other
active ingredients.
These products are being called in for full Federal regis-
tration. Producers of these products are being sent a letter
instructing them how to submit an application for registration.
E. Addresses
The required information must be submitted to the following
address:
Richard F. Mountfort, PM-23
Registration Division (TS-767C)
Office of Pesticide Programs
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460
The address for submissions to the Office of Compliance
Monitoring is:
Laboratory Data Integrity Program
Office of Compliance Monitoring (EN-342)
Environmental Protection Agency
401 M St., SW
Washington, D.C. 20460.
49
-------
TGUIDE-1
GUIDE TO TABLES
Tables A and B contain listings of data requirements
for the pesticides covered by this Registration Standard.
Table A contains generic data requirements that apply to
the pesticide in all products, including data requirements
for which a "typical formulation1" is the test substance.
Table B contains product-specific data requirements that
apply only to a manufacturing use product.
The data tables are generally organized according to the
following format:
1. Data Requirement (Column 1). The data requirements are
listed in the order in which they appear in 40 CFR Part 158.
The reference numbers accompanying each test refer to the
test protocols set out in the Pesticide Assessment Guidelines,
which are available from the National Technical Information
Service, 5285 Port Royal Road, Springfield, VA 22161.
2. Test Substance (Column 2). This column lists the composition
of the test substance required to be used for the test, as
follows:
TGAI = Technical grade of the active ingredient
PAI = Pure active ingredient
PAIRA = Pure active ingredient, radio labeled
TEP = Typical end use formulation
MP = Manufacturing use product
EP = End use product
Any other test substances, such as metabolites, will be
specifically named in Column 2 or in footnotes to the table.
3. Use pattern (Column 3). This column indicates the use
patterns to which the data requirement applies. Use patterns
are the same as those given in 40 CFR Part 158. The following
letter designations are used for the given use patterns:
A = Terrestrial, food
B = Terrestrial, non-food
C = Aquatic, food
D = Aquatic, non-food
E = Greenhouse, food
F = Greenhouse, non-food
G = Forestry
H = Domestic outdoor
I = Indoor
51
-------
TGUIDE-2
4. Does EPA have data? (Column 4). This column indicates one
of three answers:
YES - EPA has data in its files that completely satisfy
this data requirement. These data may be cited by
other registrants in accordance with data compensation
requirements of Part 152, Subpart E.
PARTIALLY - EPA has some data in its files, but such data
do not fully satisfy the data requirement. In some cases,
the Agency may possess data on one of two required species,
or may possess data on one test substance but not all.
The term may also indicate that the data available to
EPA are incomplete. In this case, when the data are
clarified, or additional details of the testing submitted
by the original data submitter, the data may be determined
to be acceptable. If this is the case, a footnote to
the table will usually say so.
NO - EPA either possesses no data which are sufficient
to fulfill the data requirement, or the data which EPA
does possess are flawed scientifically in a manner that
cannot be remedied by clarification or additional infor-
mation.
5. Bibliographic citation (Column 5). If the Agency has
acceptable data in its files, this column lists the identifying
number of each study. This normally is the Master Record
Identification (MRID) number, but may be a GS number if no
MRID number has been assigned. Refer to the Bibliography
Appendices for a complete citation of the study.
6. Must additional data be submitted? (Column 6). This
column indicates whether the data must be submitted to the
Agency. If column 3 indicates that the Agency already has
data, this column will usually indicate NO. If column 3
indicates that the Agency has only partial data or no data,
this column will usually indicate YES. In some cases, even
though the Agency does not have the data, EPA will not require
its submission because of the unique characteristics of the
chemical; because data on another chemical can be used to
fulfill the data requirement; or because the data requirement
has been waived or reserved. Any such unusual situations
will be explained in a footnote to the table.
7. Timeframe for submission (Column 7). If column 5 requires
that data be submitted, this column indicates when the data
are to be submitted, based on the issuance date of the Regis-
tration Standard. The timeframes are those established either
as a result of a previous Data Call-in letter, or standardized
timeframes established by PR Notice 85-5 (August 22, 1985).
8. Footnotes (at the end of each table). Self-explanatory.
52
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirement
Test Use Does EPA Bibliographic
Substance Patterns Have Data?!/ Citationl/
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.120 Product Chemistry (Continued)
Physical and Chemical Characteristics
(Continued)
63-7 - Density, Bulk Density, or
Specific Gravity
63-8 - Solubility
63-9 - Vapor Pressure
63-10 - Dissociation constant
63-11 - Octanol/water partition
coefficient
63-12 - pH
63-13 - Stability
Other Requirements:
64- 1 - Submittal of samples
TGAI
TGAI or PAI
PAI
PAI
PAI
TGAI
TGAI
TGAI/PAI
All
All
All
All
All
All
All
All
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Yes
Yes
Yes
Yes
Yes
Yes
Yes
No
6 Months
6 Months
6 Months
6 Months
6 Months
6 Months
6 Months
I/ Not applicable. Although product chemistry data may have been submitted in the past, the Agency has determined
that these data must be resubmitted for each pesticide. New requirements have been introduced and
previously submitted data must be updated. Therefore bibliographic citations for the old data are
not applicable.
2/ The registrant must submit details of the manufacturing process, including the relative amounts of beginning
~~ materials, a description of the equipment used to produce the product, reaction conditions,
duration of each step of the process, purification procedures and quality control measures, the name and
address of the manufactuerer, producer or supplier of each beginning material used, and a copy of
all available technical specifications, data sheets, and other documents in which the manufacturer,
producer, or supplier of the beginning material describes its composition and properties.
53
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFIURALIN
§158.120 Product Chemistry - Continued
3_/ The registrant raut provide a discussion of each impurity, including any nitrosamines, believed to be present at a level
equal to or greater than 0.1% based on knowledge of the beginning materials, all possible chemical
reactions and contamination.
4/ The registrant must analyze five (5) or more representative samples for the amount of active ingredient
and each impurity present at or greater than 0.1%, using valid analytical methods.
5/ Upper and lower limits for trifluralin, and upper limits for each impurity present at 0.1% must be provided
and certified. All nitrosamines must be identified and quantified in six samples each of technical grade and
formulation intermediate trifluralin. Two samples must be analyzed shortly after production, 3 months after production
and 6 months after production. A validated method sensitive to 0.5 ppm for detecting N-nitroso contaminants must
be used. A certified upper limit must be provided on the Confidential Statement of Formula for all nitrosamines
found.
6/ The registrant must submit quantitative methods to determine trifluralin and all impurities for which a
certified limit is required. Each method must be accompanied by validation studies of the precision and accuracy of
the method.
7/ Not required because the technical is a solid at room temperature.
54
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirement
Test Substance
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.125 Residue Chemistry
171-4 - Nature of Residue (Metabolism)
Plants PAIRA
Partially
Livestock
171-4 - Residue Analytical Method
Plant residues
PAIRA and Plant
Metabolites
TGAI and
Metabolites
Partially
Yes
Animal residues
TGAI and Metabolites
No
00024731
00026054
00093553
00105720
00105759
00124905
00125299
GS-0179-001
00093636
00105690
00105772
00022793
00024248
00047591
00047639
00059532
00067371
00067435
00080320
00105646
00105689
00105695
00105720
00105759
00125303
GS-0179-002
55
Yesl/
18 Months
Yes2/
18 Months
No
No3/
-------
TABI£ A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements
Test Substance
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.125 Residue Chemistry - Continued
171-4 - Storage Stability Data PAI
171-4 - Magnitude of the Residue -
Residue Studies for Each
Food Use
Root and Tuber Vegetables GroupS/
Carrots TEP
Potatoes
Processed Potato Products
(Chips, granules, and
dried potatoes)
TEP
EP
Partially
Yes
Yes
No
00047639
00105716
00105720
00093554
00033087
00022257
00093574
00105733
00105734
00133939
Yes4/
No
No
Yes6/
24 Months
24 Months
56
-------
TABLE A _
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Does EPA
Data Requirements Test Substance Have Data?
§158.125 Residue Chemistry - Continued
Sugar Beets TEP Yes
Processed products EP No
Turnips TEP Yes
Leaves of Root and Tuber Vegetables Group
Sugar Beet Tops TEP Yes
Turnips Tops TEP Yes
Bulb Vegetables (Alium spp. ) Groups/
Garlic TEP Yes
Onions TEP Yes
Bibliographic
Citation
00057546
00105648
00105666
00105757
00093554
00033087
00057546
00105648
00105666
00105757
00105648
00105666
00105757
00057546
00105724
00105678
00120263
Must
Additional
Data be
Submitted?
No
YesT/
No
No
No
No
No
Time Frame
for
Submission
24 Months
57
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLJURALIN
Data Requirements
Leafy Vegetables (except Brassica)
Celery
Upland Cress
Brassica Leafy Vegetables Group
Broccoli
Brussels sprouts
Cabbage
Cauliflower
Collards
Kale
Mustard Greens
Test Substance
Group9/
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
TEP
Does EPA
Have Data?
Yes
No
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Bibliographic
Citation
00093549
00105670
00105749
00105650
00105749
00105749
00105650
00105749
00105724
00105724
00105724
Must
Additional
Data be
Submitted?
No
NolO/
No
No
No
No
No
No
No
Time Frame
for
Submission
58
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Does EPA
Data Requirements Test Substance Have Data?
§158.125 Residue Chemistry - Continued
Legume Vegetables (Succulent or Dried) Group
Adzuki Beans TEP Yes
Beans, Dried-Type TEP Yes
Field Peas (Cowpeas, TEP Yes
Black-eyed peas)
Guar Beans TEP Yes
Lima Beans TEP Yes
Mung Beans TEP Yes
Peas (Succulent and Dried) TEP Yes
Snap Beans TEP Yes
Bibliographic
Citation
00022736
00105669
00105726
00022376
00105669
00105726
00105669
00105670
00033086
00105726
00105669
00105670
00105669
00105755
00022376
00033086
00057547
00105669
Must
Additional Time Frame
Data be for
Submitted? Submission
No
No
No
No
No
No
No
No
59
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLJURALIN
Does EPA
Data Requirements Test Substance Have Data?
§158.125 Residue Chemistry - Continued
Soybeans TEP Yes
Processed Food/Feed EP No
Foliage of the Legume Vegetables Group
Bean Vines and Hay TEP Yes
Peas Vines and Hay TEP Yes
Soybean Forage, Hay, and Straw TEP Yes
Fruiting Vegetables (except Cucurbits) Group
Peppers TEP Yes
Tomatoes TEP Yes
60
Must
Additional
Bibliographic Data be
Citation Submitted?
00022793 No
00030932
00067433
00094410
00096361
00104423
00105655
00105669
00105717
00105720
00105725
00105746
00124904
00128308
Yesll/
00022376 No
00105669
0010S669 No
00022793 No
00030932
00067433
00096361
00105720
00105750 No
00105726 No
00105750
00105710
Time Frame
for
Submission
24 Months
-------
TABL£ A
GENERIC DATA REQUIREMENTS FOR TRIFLJURALIN
Does EPA
Data Requirements Test Substance Have Data?
§158.125 Residue Chemistry - Continued
Cucurbit Vegetables Groupl2/
Cantaloupes TEP Yes
Bibliographic
Citation
00093555
00105726
Must,
Additional
Data be
Submitted?
No
Time Frame
for
Submission
Cucumbers
TEP
Yes
00093555
No
Watermelons
Citrus Fruits Group
Processed Food/Feed
Stone Fruits Groupl4/
Apricots
Nectarines
Peaches
Plums (Fresh prunes)
TEP
EP
TEP
TEP
TEP
TEP
Yes
Partially
Yes
Yes
Yes
Yes
00105670
00105677
00105667
00105675
00105667
00105675
00105667
00105675
00105675
00105735
No
Yesl3/
No
No
No
No
24 Months
61
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements Test Substance
§158.125 Residue Chemistry - Continued
Small Fruits and Berries GrcuplS/
Grapes TEP
Tree Nuts Group TEP
Cereal Grains Groupl6/
Barley TEP
Corn TEP
Sorghum TEP
Wheat TEP
Forage, Fodder, and Straw of
Cereal Grains Group20/
Barley Forage, Hay and Straw TEP
Corn Forage, Fodder and Silage TEP
Sorghum Forage, Fodder, Silage and
Hay TEP
Does EPA Bibliographic
Have Data? Citation
Yes 00105678
Yes 00105675
00105726
Yes 00070736
00105704
Partially 00032811
00105697
00105726
Partially 00105704
00105726
Partially 00070736
00105681
00105726
Yes 00070736
00105704
Partially 00032811
00105726
Yes 00105704
62
Must
Additional
Data be
Submitted^
No
No
No
YeslT/
YeslS/
Yesl9/
No
Yes21/
No22/
Time Frame
for
Submission
24 Months
24 Months
24 Months
24 Months
-------
TABL£ A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements Test Substance
§158.125 Residue Chemistry - Continued
Wheat forage, hay, and straw TEP
Nongrass Animal Feeds (forage, fodder, straw,
and hay) Group24/
Alfalfa Forage and Hay TEP
Miscellaneous Commodities
Asparagus TEP
Flax TEP
Cottonseed TEP
Hops TEP
Mustard seed TEP
Okra TEP
Does EPA Bibliographic
Have Data? Citation
Yes 00070736
00105681
Partially 00093637
00105691
00105726
Yes 00105696
00105702
Partially 00084581
Partially 00093190
00105669
00105713
00105726
00105729
00105731
00105751
00105759
00105780
00105781
00124904
Yes 00105678
Partially 00067371
Yes 00105669
Must
Additional
Data be
Submitted?
No23_/
Yes25/
No
Yes26/
Yes27/
No
No28/
No
Time Frame
for
Submission
24 Months
24 Months
24 Months
63
-------
TABI£ A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Does EPA
Data Requirements Test Substance Have Data?
§158.125 Residue Chemistry - Continued
Peanuts (Nutmeats, Vines, Hay, TEP Partially
and Hulls)
Peppermint TEP Partially
Rape Seed TEP Yes
Saf flower Seed TEP Yes
Spearmint TEP Yes
.Sugarcane TEP Partially
Sunflower Seed and Forage TEP Partially
171-4 - Magnitude of the Residues in
Meat, Milk, Poultry and Eggs TGAI or Plant Partially
Metabolites
Bibliographic
Citation
00026049
00059531
00067222
00105646
00105683
00047639
00067371
00105726
00105750
00105683
00105668
00105674
00105727
00105730
00057545
00067371
00067430
00105673
00023105
00080320
00080322
00093634
00093636
00105772
Must
Additional
Data be
Submitted?
Yes29/
Yes30/
No
No
No31/
Yes32/
Yes33/
Yes34/
Time Frame
for
Submission
24 Months
24 Months
24 Months
24 Months
18 Months
64
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
I/ Registrants must submit data depicting (a) the distribution and nature of residues of [l^C] trifluralin (ririglabeled)
in mature, fresh and dry corn kernels, and in forage harvested at intervals following an over-the-top spray application
at a rate sufficiently high to permit l^C-residue characterization and; (b) the distribution and nature of residues
of C^C] trifluralin (ring-labeled) in a mature leafy or Brassica leafy vegetable (such as celery, cabbage, or
collards) following a preplant soil application at a rate sufficiently high to permit 14C-residue characterization.
Representative samples from the above-described tests must also be analyzed by the enforcement methods to
ascertain that all metabolites of concern are detected.
2/ Registrants must submit metabolism studies utilizing ruminants and poultry. Animals must be dosed for three days with
ring-labeled C^C] trifluralin at a level sufficient to make residue identification and quantification possible.
Milk and eggs must be collected twice daily during the dosage period. Animals must be killed within 24 hours of the
final dose. The distribution and characterization of residues must be determined in milk, eggs, liver, kidney, muscle,
and fat. Samples from the studies should also be analyzed by the enforcement methods to ascertain that all
metabolites of concern are determined.
3/ Presently, no residue analytical methods in animals are necessary. However, depending on the outcome of
animal metabolism studies, analytical methods for animal residues may be required by the Agency.
4_/ The storage intervals and conditions of storage of samples used to support all established tolerances for residues
must be submitted. These data must be accompanied by data depicting the percent decline in residues at the time and
under the conditions specified. (No additional stability studies are required for plant commodities stored at room
temperature in polyethylene bags in the dark for up to 4 months or frozen for up to 10 months). On receipt of these
data, the adequacy of the tolerances will be reevaluated. All residue data requested in this Standard
must be accompanied by data regarding storage length and conditions of storage of samples analyzed. These data must
be accompanied by data depicting the stability of residues under the conditions and for the time intervals specified,
with the exception of plant commodities stored at room temperature in polyethylene bags in the dark for < 4 months or
frozen for < 10 months. Since the nature of residues in plants and animals has not been adequately described, if the
requested metabolism data indicate the presence of residues of toxicological concern in animal commodities or
additional residues of toxicological concern in plant commodities, data depicting the stability of such residues in
storage will be required.
J5/ A crop group tolerance is not appropriate unless residue data are submitted for radishes,
~~ a representative commodity.
65
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
6/ Registrants must submit residue data for processed potato commodities (chips, granules, and dried potatoes) processed
from potatoes bearing measurable, weathered residues. Should residues concentrate upon processing, appropriate
food/feed additive tolerances may be indicated. Establishment of such tolerances will depend on the Agency's future
policy with regard to the Delaney Clause and FIFRA.
7/ Registrants must submit residue data from dehydrated pulp, molasses, and refined sugar, processed from sugar
beets bearing measurable, weathered residues. Should residues concentrate in processed products, appropriate
food/feed additive tolerances may be indicated. Establishment of such tolerances will depend on the Agency's
future policy with regard to the Delaney Clause and FIFRA.
8/ A crop group tolerance is not appropriate unless residue data are submitted for onions (green),
a representative commodity.
9/ A crop group tolerance is not appropriate unless residue data are submitted for lettuce (head and
leaf) and spinach, representative commodities of this group.
10/ There are no registered uses of trifluralin on upland cress. Within 6 months from the date of
issuance of this Standard, registrants must either propose a use, or petition the Agency to revoke the tolerance.
ll/ Residues must be determined in meal, hulls, soapstock, crude oil, and refined oil prepared from beans bearing
measurable weathered residues. It may be necessary to use exaggerated rates to obtain measurable residues in
the raw agricultural commodity (beans). If residues in any of these commodities exceed those found in soybeans,
an appropriate food/feed additive tolerance may be indicated. Establishment of such tolerances will depend on
the Agency's future policy with regard to the Delaney Clause and FIFRA.
12/ A crop group tolerance is no longer appropriate unless residue data are submitted for summer
squash, a respresentative commodity.
13/ Registrants must submit data depicting the residues of trifluralin in dried pulp, oil, molasses, and juice processed
from oranges bearing measurable weathered residues. If residues concentrate in any processed commodity, appropriate
food/feed additive tolerances may be indicated. Establishment of such tolerances will depend on the Agency future
policy with regard to the Delaney Clause and FIFRA.
66
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
14/ Proposed use direction and additional residue data are required for cherries, a representative commodity of this group.
15/ A crop group tolerance is not appropriate unless residue data are submitted for blackberries or another Rubus species,
blueberries, cranberries, and strawberries, representative commodities of this group.
16/ The established crop group tolerance (0.05 ppm in or on grain crops except fresh corn and rice grain") is not appropriate
because: (a) There are no registered uses for rice, a representative commodity of this group, (b) The use directions
are not uniform for the representative commodities of this group, (c) Additional data are required for corn and sorghum
representative commodities of this group.
17/ Registrants must submit data depicting (a) residues in or on grain of field corn treated over-the-top with an EC
formulation at 1 Ib ai/A and harvested at the shortest posttreatment interval consistent with established good
agricultural practice. Tests must be conducted in IA, IL, and OH which represent the major corn growing regions of
the country (Agricultural Statistics, 1983, p. 32) and; (b) residues in or on wet and dry milling products, including
crude and refined oil, processed from field corn grain bearing measurable weathered residues. Exaggerated application
rates may be required to obtain measurable residues in field corn grain. If concentration occurs, appropriate food
additive tolerances may be indicated. Establishment of such tolerances will depend on the Agency's future policy
with regard to the Delaney Clause and FIFRA.
18/ Registrants must submit data depicting residues in flour and starch processed from sorghum grain bearing measurable
weathered residues of trifluralin. If residues are found to concentrate in these processed commodities, an appropriate
food additive tolerance may be indicated. Establishment of such tolerances will depend on the Agency's future policy
with regard to the Delaney Clause and EIFRA.
19/ Registrants must submit data depicting residues in or on milled products (bran, flour, middlings, shorts) processed
from wheat grain bearing measurable weathered residues. These data are to be translated to barley. Exaggerated
application rates may be needed to obtain measurable residues in the wheat grain. If concentration occurs, appropriate
food additive tolerances may be indicated. Establishment of such tolerances will depend on the Agency's future
policy with regard to the Delaney Clause and FIFRA.
67
-------
TABLE A
GENERIC DATA REQUIREMENTS. FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
20/ A crop group tolerance is not appropriate because (a) the use directions are not uniform for the representative
commodities of this group; and (b) additional residue data must be submitted are required for corn, a representative
commodity of this group.
21/ Registrants must submit data depicting residues in or on forage, fodder, and silage of field corn treated over-the-top
with an EC formulation at 1 Ib ai/A and harvested at intervals thereafter. Fodder should be sampled at normal harvest.
Tests must be conducted in IA, IL, and OH, to represent the major corn-growing regions of the country (Agricultural
Statistics, 1983, p. 32). Appropriate pregrazing and prefeeding intervals should be proposed. Also, a tolerance for
residues in or on silage must be proposed.
22/ The adequacy of the established tolerance cannot be reassessed at this time because insufficient data were submitted
for fodder, silage and hay. However, no data are required because the data requested for corn forage, fodder,
and straw will be translated to sorghum. Appropriate pregrazing and prefeeding intervals should be proposed. Tolerance
must be proposed for residues in or on sorghum hay and silage.
23/ The available data for wheat and barley straw, considered together, indicate that the tolerance for residues in or on
straw should be increased to 0.1 ppm particularly when the low recovery values are taken into account. Also, a
tolerance of 0.1 ppm should be proposed for residues in or on wheat hay.
24/ A crop group tolerance is not appropriate unless residue data are submitted for alfalfa, a representative crop (refer to
the following section on alfalfa for details of data gaps) and clover, representative commodities of this group.
25/ Registrants must submit data depicting (a) residues in or on alfalfa forage and alfalfa hay (dried to 10% water content)
following a single postemergence application to established alfalfa with a G and EC formulation (in separate tests) at
1 Ib ai/A. Samples must be obtained on the day of treatment and at regular intervals thereafter to elucidate the
pattern of residue decline (this information is needed to determine the necessity of a PHI or pregrazing interval).
Tests must be conducted in CA,-MN, and NY or PA since these States represent the major U.S. alfalfa hay production
regions (Agricultural Statistics, 1984, p. 247); and (b) data reflecting residues in or on seed processed from alfalfa
hay bearing measurable weathered residues (use exaggerated rates, if necessary, to obtain measurable residues). If
the concentration of residues in alfalfa seed is higher than in hay, an appropriate food or feed additive tolerance
must be proposed. Since multiple cuttings may be obtained from established alfalfa fields, the registrant must
propose a label amendment specifying the maximum number of applications permitted per year.
68
-------
-TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
26 / Registrants must submit (a) residue data for flax straw harvested after application (in separate tests) of a G and EC
formulation at 1 Ib ai/A as a preplant broadcast application. Tests must be conducted in ND or SD, States which
represent the major U.S. flax production region (Agricultural Statistics, 1983, p. 118). Alternatively, a feeding
restriction may be proposed and; (b) residue data for flax (linseed) meal and hulls derived from flax seed bearing
measurable, weathered residues. Should concentrations of residues occur, appropriate feed additive tolerances
may be indicated. Establishment of such tolerances will depend on the Agency's future policy with regard to the
Delaney Clause and FIFRA. (Data required for other oilseed crops may be translated to processed commodities of flax.)
27/ Registrants must submit data depicting residues in or on meal, hulls, soapstock, and crude and refined oil
processed from seed bearing measurable residues. It may be necessary to use exaggerated rates to obtain measurable
residues in the seed. If concentration occurs, appropriate food/feed additive tolerances may indicated. Establishment
of such tolerances will depend on the Agency's future policy with regard to the Delaney Clause and FIFRA. And
(b) residues of trifluralin in or on cotton forage harvested at intervals following a preplant broadcast of an EC at
2 Ib ai/A from tests conducted in MS and TX and following a postemergence broadcast application of a G and (in separate
tests) an EC formulation at 1 Ib ai/A. Samples from the postemergence broadcast application must be collected on the
day of treatment and at intervals thereafter. Postemergence tests must be conducted in AZ, CA, MS, and TX which
represent the major cotton-growing regions of the country (Agricultural Statistics, 1983, p. 62). A tolerance must be
proposed. Alternatively, a grazing restriction may be proposed and no additional data submitted.
28/ A tolerance has neither been proposed nor established for residues of trifluralin in or on mustard seeds. The -
registrant must eliminate the use directions for mustard grown for seed on the relevant federal labels, or
propose a tolerance for residues in or on mustard seed.
29/ Registrants must submit data depicting (a) residues in or on peanut vines and hay collected at intervals following
a preemergence broadcast application of the 10% WP or a preplant (immediately prior to planting)
broadcast application of the 4 Ib/gal EC formulation at 0.75 Ib ai/A. Tests must be conducted in GA, TX, and FL,
which represent the major U.S. peanut product regions (Agricultural Statistics, 1983, p. 126). Pregrazing and
and prefeeding intervals must be proposed. Upon receipt of the requested data, separate tolerances for residues
in or on peanut vines and hay must be established and the tolerance for residues in or on members of the now-
obsolete forage legumes group should be deleted. Alternatively, grazing and feeding restrictions may be proposed
and no residue data submitted and; (b) residues in meal, crude and refined oil, and soapstock processed
from nutmeats bearing measurable weathered residues. Use of exaggerated application rates may be required to
obtain measurable weathered residues in nutmeats. If residues are found to concentrate, appropriate food/feed
additive tolerances must be proposed.
69
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.125 Residue Chemistry - Continued
30/ Registrants must submit processing data for peppermint oil and spent hay derived from peppermint hay bearing
measurable, weathered residues. Exaggerated rates may be required to obtain detectable residues of trifluralin.
If residues concentrate in spent peppermint hay, an appropriate feed additive tolerance may be indicated. Establishment
of such a tolerance will depend on the Agency's future policy with regard to the Delaney Clause and FIFRA.
31/ Registrants must submit processing data for spearmint oil and spent hay derived from spearmint hay bearing measurable,
weathered residues. Exaggerated rates may be required to obtain detectable residues of trifluralin. If
residues concentrated in spent spearmint hay, .an appropriate feed additive tolerance may be indicated.
Establishment of such a tolerance with depend on the Agency's future policy with regard to the Delaney Clause
and FIFRA. However, no data are required because data derived from peppermint oil and spent hay processing
will be translated to spearmint.
32/ Registrants must submit data depicting (a) residues in or on molasses, refined sugar and bagasse processed
from cane bearing measurable weathered residues. Use of exaggerated application rates may be necessary to
obtain measurable residues in cane. If concentration occurs, appropriate food/feed additive tolerances must
be proposed and; (b) residues in or on sugarcane forage harvested on the day of and at intervals
following a layby application with the 4 or 5 Ib/gal EC formulation at 2 Ibs ai/A. Tests must be conducted
in TX and LA. A tolerance must be proposed for residues in or on forage; alternatively, the registrant may
propose a grazing restriction and submit no data.
33/ Registrants must submit (a) data depicting residues of trifluralin in or on sunflower forage harvested
at intervals following a preplant application of a G and, in separate tests, an EC formulation at 1 Ib ai/A.
Tests must be conducted in ND and MN, which represent the major sunflower production region of the U.S.
(Agricultural Statistics, 1983, p. 133). A tolerance must be proposed; alternatively, a grazing restriction
may be proposed and no data submitted and; (b) residue data from sunflower meal, hulls, crude oil, and refined
oils processed from sunflower seeds bearing measurable, weathered residues. If residues are shown to
concentrate upon processing, then appropriate food/feed additive tolerances may be indicated. Establishment
of such tolerances will depend on the Agency's future policy with regard to the Delaney Clause and FIFRA.
34/ The nature of the residue in animals (including meat, milk, poultry and eggs) is not adequately understood.
Presently, no tolerances exist for residues of trifluralin in animal products. On receipt of the data
requested in the section entitled "Nature of Residue (Metabolism) Livestock^/" the adequacy of the residue
data for animal products will be assessed and, if appropriate, the need for any proposals for tolerances
for residues in animal products will be determined.
70
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements
§158.130 Environmental Fate
DEGRADATION STUDIES-LAB:
161-1 - Hydrolysis
Photodegradation
161-2 - In water
161-3 - On soil
161-4 - In Air
METABOLISM STUDIES-LAB:
162-1 - Aerobic Soil
162-2 - Anaerobic Soil
162-3 - Anaerobic Aquatic
162-4 - Aerobic Aquatic
MOBILITY STUDIES:
Test
Substance
!
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
TGAI or PAIRA
163-1 - Leaching and TGAI or PAIRA
Adsorption/Desorption
163-2 - Volatility (Lab)
163-3 - Volatility (Field)
TEP
TEP
Use
Patterns
A,B,H,D
A,B,H,D
A,B,H
A,B,H
A,B,H
A,B,H
A,B,H,D
A,B,H,D
A,B,H,D
A,B,H
A,B,H
Must
Additional
Does EPA Bibliographic Data be
Have Data? Citation Submitted?
Yes 00131135
No
No
No
No
No
No
No
No
No
No
Nol/
Yes
Yes
No
Yes
Yes2/
Yes
Yes
Yes
Yes
Yes3_/
Time Frame
for
Submission
9 Months
9 Months
27 Months
27 Months
27 Months
27 Months
12 Months
12 Months
15 Months
71
-------
TARTF. A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements
§158. 130
Test
Substance
Use
Patterns
Must
Additional
Does EPA Bibliographic Data be
Have Data? Citation Submitted?
Time Frame
for
Submission
Environmental Fate - Continued
DISSIPATION STUDIES-FIEID:
164-1
164-2
164-3
164-4
165-5
- Soil
- Aquatic (Sediment)
- Forestry
- Combination and
Tank Mixes
- Soil, Long-term
TEP
TEP
TEP
TEP
A,B,H
A,B,H,D
N/A4/
N/A4/
A,B,H
No Yes
No Yes
No Yes5/
27 Months
27 Months
50 Months
ACOMJLATION STUDIES:
165-1
165-2
165-3
165-4
165-5
- Rotational Crops
(Confined)
- Rotational Crops
(Field)
- Irrigated Crops
- In Fish
-In Aquatic Nontarget
Organisms
PAIRA
TEP
TEP
TGAI or PAIRA
TEP
A,B,H
A,B,H
A,B,H,D
A,B,H,D
A,B,H,D
No Yes
No Yes6/
No Yes
No
Yes
No
Yes
39 Months
50 Months
39 Months
12 Months
12 Months
72
-------
TABI£ A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.130 Environmental Fate - Continued
I/ Trifluralin is in a class of immobile chemicals which are unlikely to leach to ground water.
2/ An anaerobic soil metabolism study is not required if an acceptable anaerobic aquatic metabolism study is submitted
on time.
3/ This data requirement is deferred pending results from the laboratory volatility data.
4/ Not required for this chemical.
5/ Data requirement is contingent upon the results of the aerobic soil metabolism/terrestrial field
dissipation studies.
6/ Data requirement is deferred pending results from the confined accumulation studies on rotational crops.
73
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Test
Data Requirements Substance
Use Does EPA
Patterns Have Data?
Bibliographic
Citation
Must
Additional Time Frame
Data be for
Submitted? Submission
§158.135 Toxicology
ACUTE TESTING:
81-1
81-2
81-3
81-7
- Acute Oral Toxicity - Rat
- Acute Dental Toxicity
- Rabbit
- Acute Inhalation Toxicity
- Rat
- Delayed
Neurotoxicity - Hen
TGAI
TGAI
TGAI
TGAI
A,B,H Yes
A,B,H Yes
A,B,H Yes
N/A1/
00105776
00157486
00105776
00157482
00085087
00062921
00155261
No
No
No
SUBCHRONIC TESTING:
82-1
82-2
82-3
82-^1
82-5
- 90-Day Feeding:
- Rodent, and
- Nonrodent (Dog)
- 21-Day Dermal - Rabbit
- 90-Day Dermal - Rabbit
- 90-Day Inhalation:
- Rat
- 90-Day Neurotoxicity:
- Hen
- Mammal
TGAI
TGAI
TGAI
TGAI
TGAI
A,B,H Yes
A,B,H Yes
N/A3/
N/A3/
N/A3/
N/A1/
74
00083650
00134326
00083650
00134326
No2/
No2_/
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFOJRALIN
Test
Data Requirements Substance
§158.135 Toxicology - Continued
CHRONIC TESTING:
83-1 - Chronic Toxicity - TGAI
2 species:
- Rodent, and
- Nonrodent (Dog)
83-2 - Oncogenicity - TGAI
2 species:
- Rat (preferred), and
- Mouse (preferred)
83-3 - Teratogenicity - TGAI
2 species:
- Rat
- Rabbit
83-4 - Reproduction - Rat TGAI
2-generation
MUTAGENICI1Y TESTING:
84-2 - Gene Mutation (Ames Test) TGAI
84-2 - Structural Chromosomal TGAI
Aberration
84-4 - Other Genotoxic Effects TGAI
Use Does EPA
Patterns Have Data?
A,B,H
Partially
Yes
A,B,H
Yes
Yes
A,B,H
Yes
Yes
A,B,H Yes
A,B,H Yes
A,B,H Yes
A,B,H Yes
75
Bibliographic
Citation
00044337
00044338
00083645
00044337
00044338
00152419
00152420
00152421
00083645
GS-0179-009
00162543
00126661
00129059
00126661
00129059
Must
Additional Time Frame
Data be for
Submitted? Submission
Yes4/
No
No
No
No
No
No
No
No
No
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements
Test
Substance
Use
Patterns
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.135 Toxicology - Continued
SPECIAL TESTING
85-1 - General Metabolism
85-2 - Dermal Penetration
86-1- Domestic Animal
PAI or PAIRA A,B,H
Choice A,B,H
Choice A,B,H
No
No
Yes
00105776
00137468
00085087
00062921
00138224
Yes5/
Yes
No
24 Months
12 Months
76
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.135 Toxicology - Continued
I/ This study is not required because trifluralin is not an organophosphate or carbamate which will cause acetyl
cholinesterase depression, nor is it structurally related to a substance that induces neurotoxicity.
2/ The data submitted are considered Core Supplementary; however, these studies need not be repeated because
chronic studies are available.
3/ Not applicable to exposure conditions.
4/ Additional data in the rat is required to resolve the adverse effects on the kidney since
a NOEL for non-oncogenic kidney effects was not demonstrated in the 1980 Eli Lilly study. Dosing
levels should overlap the 1980 Eli Lilly rat study, but include at least one dose lower than
813 ppm (the lowest dose tested). A 2-year chronic feeding study is not necessarily required
to elucidate these effects. Registrants are requested to consult with the Agency regarding
a suitable protocol for this study (particularly regarding the duration of the study).
V Detailed metabolism of trifluralin in mammals sufficient to isolate and characterize metabolites
which are (1) excreted via the urine, (2) formed in the urinary tract, (3) and/or abosrbed
via the urinary tract are required.
77
-------
TABLE A
GENERIC DATA REQUIREMENTS FDR TRIFLURALIN
Data Requirements
Test
Substance
Use
Patterns
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.140 Reentry Protection
132-1 - Foliar Dissipation TEP
132-1 - Soil Dissipation TEP
133-3 - Dermal Exposure TEP
133-4 - Inhalation Exposure TEP
§158.142 Spray Drift
201-1 - Droplet Size Spectrum TEP
202-1 - Drift Field Evaluation TEP
A,B
A,B
N/A1/
N/A1/
N/A1/
N/A1/
No
No
Yes2/
Yes2/
6 Months
6 Months
\J Not applicable to exposure conditions.
2_/ The Agency is requiring droplet spectrum and spray drift field evaluation tests due to the toxicity of the
chemical to certain aquatic organisms and its methods of application (other than soil incorporation).
The droplet spectrum study is to be performed to reflect the nozzle and other equipment types to be used
in the application of trifluralin to crops and non-crops. The spray drift field evaluation is to be performed
to reflect the application equipment, use pattern, and typical locations of use, which includes different
weather factors, in the application of trifluralin for these uses. The spray drift droplet spectrum and field evaluation
may be done together in order to evaluate the droplet spectrums that are associated with actual field use patterns.
78
-------
TARTF. A
GENERIC DATA REQUIREMENTS FOR TRIFEURALIN
Test Use
Data Requirements Substance Patterns
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional Time Frame
Data be for
Submitted? Submission
§158.145 Wildlife and
Aquatic Organisms
AVIAN AND MAMMALIAN TESTING
71-1
71-2
71-3
71-4
.71-5
- Avian Acute Oral Toxicity TGAI A,B
- Avian Subacute Dietary
Toxicity
- Upland Game Bird, and TGAI A,B
- Waterfowl TGAI A,B,
- Wild Manual Toxicity
- Avian Reproduction
- Upland Game Bird, and TGAI A,B
- Waterfowl TGAI A,B
- Simulated Field Testing
- Mammals and Birds TEP
- Actual Field Testing
- Mammals and Birds TEP
Yes
Yes
Yes
N/A1/
Yes
Yes
N/A1/
N/A1/
00137573
GS-9999-001
00138857
00138858
00131132
00131134
00131132
00131134
No
No
No
No
No
79
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Test Use Does EPA
Data Requirements Substance Patterns Have Data?
Must
Additional Time Frame
Bibliographic Data be for
Citation Submitted? Submission
§158. 145 Wildlife and
Aquatic
Organisms - Continued
AQUATIC ORGANISMS TESTING
72-1 -
72-2 -
72-3 -
Freshwater Fish Toxicity
- Cold water Fish Species, TGAI A,B Yes
and
- Warm water Fish Species TGAI A,B, Yes
Acute Toxicity to
Freshwater Invertebrates TGAI A,B Yes
Acute Toxicity to
Estuarine and Marine
Organisms
- Fish TGAI A,B No
- Mollusk TGAI - A,B No
- Shrimp TGAI A,B No
GS0144-012 No
GS0144-012 No
.^
GSO144-012 No
Yes2/ 12 Months
Yes2/ 12 Months
Yes2/ 12 Months
72-4 - Fish Early Life Stage,
and
- Aquatic Invertebrate
Life-Cycle
TGAI
A,B
Yes
05008271
No
80
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Test
Data Requirements Substance
§158.145 Wildlife and
Aquatic Organisms - Continued
72-5 - Fish - Life-Cycle TGAI
72-6 - Aquatic Organism TGAI, PAI or
Use
Pattern
A,B
A,B
Does EPA
Have Data?
Yes
No
Bibliographic
Citation
05008271
Must
Additional
Data be
Submitted?
NO
ReservedV
Time Frame
for
Submission
Accumulation
- Crustacean
- Fish
- Insect Nymph
- Mollusk
Degradation
Product
72-7 - Simulated Field Testing
- Aquatic Organism
TEP
A,B
Yes
00155972
00155973
00155974
00155975
No
- Actual Field Testing
- Aquatic Organisms
TEP
A,B
Partially
00155978
Yes4/
81
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Data Requirements
Test
Substance
Use
Pattern
Does EPA
Have Data?
Bibliographic
Citation
Must
Additional
Data be
Submitted?
Time Frame
for
Submission
§158.155 Nontarget Insect
NONTARGET INSECT TESTING -
AQUATIC INSECTS;
142-1 - Acute toxicity to
aquatic insects
142-1 - Aquatic insect
life-cycle study
142-3 - Simulated or actual
field testing for
aquatic insects
143-1 - NONTARGET INSECT
TESTING - PREDATORS
thru AND PARASITES
143-3
No
No
No
No
(Reserved)3/
(Reserved)3/
(Reserved)3_/
(Reserved)3/
I/ Since acute contact tests show low toxicity to bees, no further testing is required.
2/ This requirement is reserved pending development of test methodology.
_3_/ This requirement is reserved pending further evaluation to determine what and when
data should be required, and to develop appropriate test methods.
82
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
Test Use Does EPA
Data Requirements Substance Pattern Have Data?
§158.155 Nontarget Insect
NONTAFGET INSECT TESTING -
POLLINATORS:
i
141-1 - Honeybee acute
contact toxicity TCAI A, B,H Yes
Bibliographic
Citation
00028772
05001991
Must
Additional
Data be
Submitted?
No
Tine Frame
for
Submission
141-2 - Honeybee - toxicity TEP
of residues on
foliage
141-4 - Honeybee subacute
feeding study
141-5 - Field testing for TEP
pollinators
A,B,H
A,B,H
No
No
Nol/
(Reserved)2/
Nol/
83
-------
TABLE A
- . _ GENERIC DATA REQUIREMENTS FOR TRIFLURALIN
§158.145 Wildlife and Aquatic Organisms - Continued
I/ The lav toxicity of trifluralin to'avian species does not support the need for these data.
2/ Marine/estuarine toxicity data are required to support uses in coastal areas (i.e., cotton, soybeans,
sugarcane, rights-of-way, etc.)
3/ Aquatic organism accumulation is reserved pending receipt of pertinent environmental fate information.
4/ Aquatic field testing is required because of the high toxicity and expected exposure in aquatic habitat
via soil run-off. Use patterns of particular concern include corn, soybeans, cotton, sorghum, small
grains and peanuts. The Data Call-in Notice for trifluralin dated August 25, 1982, required registrants of
pesticide products containing trifluralin to submit field monitoring data to the Agency. Based upon the results of
this monitoring study, the Agency will now require monitoring of trifluralin residues in fish from ponds, streams
and rivers in high use areas throughout the United States. An acceptable protocl must be submitted for evaluation
and approval within 90 days of the issuance of this standard. The protocol must, at a minimum, address multi-year
design (several years with sampling during the four seasons) and rationale for regional test site selection.
84
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRIFLURALIN
Test
Data Requirements Substance
§158.120 Product Chemistry
Product Identity:
61-1 - Product Identity and
Disclosure of
of Ingredients
61-2 - Description of Beginning
Materials and
Manufacturing Process
61-3 - Discussion of Formation of
Impurities
MP
MP
MP
Use
Pattern
All
All
,
' All
Does EPA
Have Data?
N/A
N/A
N/A
Must
Bibliographic Additional
Citation Data be
Submitted?
N/A
N/A
N/A
Yes
Yesl/
Yes2/
Time Frame
for
Submission
6 Months
6 Months
6 Months
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Methods
to Verify
Certified Limit
MP
MP
MP
All
All
All
N/A
N/A
N/A
N/A
N/A
N/A
Yes3_/
Yes4/
Yes5/
12 Months
12 Months
12 Months
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
MP
MP
MP
All
All
All
N/A
N/A
N/A
N/A
N/A
N/A
Yes
Yes
Yes
6 Months
6 Months
6 Months
85
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRIFLURALIN
Test
Data Requirements Substance
Use
Pattern
Does EPA
Have Data?
Must
Bibliographic Additional
Citation Data be
Submitted?
Time Frame
for
Submission
§158.120 Product Chemistry (Continued)
Physical and Chemical Characteristics
(Continued)
63-7 -
63-12
63-14
63-15
63-16
63-17
63-18
63-19
63-20
Other
64- 1
- Density, Bulk Density, or
Specific Gravity
- pH
- Oxidizing or Reducing
Action
- Flammability
- Explodability
- Storage Stability
- Viscosity
- Miscibility
- Corrosion Characterictics
Requirements :
- Submittal of samples
MP
1 MP
MP
MP
MP
MP
MP
MP
MP
MP
All
All
All
All
All
All
All
All
All
All
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Yes
Yes
Yes
No
Yes
Yes
No
No
Yes
No
6 Months
6 Months
6 Months
6 Months
15 Months
15 Months
86
-------
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAININ3 TRIFLURALIN
I/ The registrant must submit details of the manufacturing process, including the relative artounts of beginning materials,
a description of the equipment used to produce the product, reaction conditions, the duration of each step of the proces,
purification procedures and quality control measures, the name and address of the manufacturer, producer or supplier of
each beginning material used, and a copy of all available technical specifications, data sheets, and other documents in
which the manufacturer, producer, or supplier of the beginning material describes its composition and properties.
2/ For all manufacturing use products and formulation intermediates, the registrant must provide a discussion of each
impurity, including any N-nitroso compounds, believed to be present at levels equal to or greater than 0.1%,
based on knowledge of the beginning materials, all possible chemical reactions and any contamination.
3/ For all manufacturing use products and formulation intermediates, registrants must analyze 5 or more representative
samples for the amount of active ingredient and each impurity present for which a certified limit is
required. Valid analytical methods must be used.
4/ Upper and lower limits for trifluralin and for each intentially added inert ingredient, and upper limits
for each impurity present at 0.1% (w/w) must be provided and certified. Two samples of each must be analyzed
shortly after production, 3 months after production and 6 months after production. A validated method
sensitive to 0.5 ppm of N-nitroso compounds must be used. An upper limit must be provided and certified
for all N-nitroso compounds found.
5/ The registrant must submit quantitative methods to determine trifluralin and all impurities and inerts
for which a certified limit is required). Each method must be accompanied by validation studies of the precision and
accuracy of the method.
NOTE: No registrants of trifluralin manufacturing-^use products have submitted adequate product chemistry data.
87
-------
•TABUS B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING TRIFLURAKLN
Use
Data Requirements Pattern
§158.135 Toxicology
ACUTE TESTING
81-1 - Acute Oral Toxicity - Rat MP
81-2 - Acute Dental Toxicity MP
81-3 - Acute Inhalation Toxicity MP
- Rat
81-4 - Primary Eye MP
81-5 - Primary Dermal MP
81 -6 - Dermal Sensitization - MP
Guinea Pig
Does EPA
Have Data?
Yes
Yes
Yes
Yes
Yes
Yes
Bibliographic
Citation
00105776
00105776
00085087
00062921
00036607
00036607
00137468
00138224
Must
Additional
Data be
Submitted?
No
No
No
No
No
No
Time Frame
for
Submission
88
-------
APPENDIX II
LABELING APPENDICES
89
-------
SUMMARY-1
LABEL CONTENTS
40 CFR 162.10 requires that certain specific labeling
statements appear at certain locations on the label. This
is referred to as format labeling. Specific label items listed
below are keyed to the table at the end of this Appendix.
Item 1. PRODUCT NAME - The name, brand or trademark is
required to be located on the front panel, preferably centered
in the upper part of the panel. The name of a product will
not be accepted if it is false or misleading.
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
Item 3. NET CONTENTS - A net contents statement is
required on all labels or on the container of the pesticide.
The preferred location is the bottom of the front panel
immediately above the company name and address, or at the end
of the label text. The net contents must be expressed in the
largest suitable unit, e.g., "1 pound 10 ounces" rather than
"26 ounces." In addition to English units, net contents may
be expressed in metric units. [40 CFR 162.10(d)]
Item 4. EPA REGISTRATION NUMBER - The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase "EPA Registration No.," or "EPA
Reg. No." The registration number must be set in type of a
size and style similar to other print on that part of the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency.
[40 CFR 162.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment
number, preceded by the phrase "EPA Est." is the final estab-
lishment at which the product was produced, and may appear
in any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of
the package if the EPA establishment number on the immediate
container cannot be clearly read through such wrapper or container
[40 CFR 162.10(f)]
Item 6A. INGREDIENTS STATEMENT - An ingredients statement
is required on the front panel. The ingredients statement must
contain the name and percentage by weight of each active ingredient
and the total percentage by weight of all inert ingredients.
The preferred location is immediately below the product name.
The ingredients statement must run parallel with, and be clearly
distinguished from, other text on the panel. It must not be
placed in the body of other text. [40 CFR 162.10(g)]
90
-------
SUMMARY-2
Item 6B. POUNDS PER GALLON STATEMENT - For liquid agricul-
tural formulations, the pounds per gallon of active ingredient
must be indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS - Front panel
precautionary statements must be grouped together, preferably
within a block outline. The table below shows the minimum type
size requirements for various size labels.
Size of Label Signal Word "Keep Out of Reach
on Front Panel Minimum Type Size of Children"
in Square Inches All Capitals Minimum Type Size
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 • 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - The statement
"Keep Out of Reach of Children" must be located on the front
panel above the signal word except where contact with children
during distribution or use is unlikely. [40 CFR 162.10(h)(1)(ii)]
Item 7B. SIGNAL WORD - The signal word (DANGER, WARNING,
or CAUTION) is required on the front panel immediately below
the child hazard warning statement. [40 CFR 162.10 (h)(l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, dermal,
or inhalation toxicity, the word "Poison" shall appear on the
label in red on a background of distinctly contrasting color and
the skull and crossbones shall appear in immediate proximity to
the word POISON. [40 CFR 162.10(h)(1)(i)]
Item 7D. STATEMENT OF PRACTICAL TREATMENT - A statement
of practical treatment (first aid or other) shall appear on
the label of pesticide products in toxicity Categories I,
II, and III. [40 CFR 162.10(h)(1)(iii)]'
Item 7E. REFERRAL STATEMENT - The statement "See Side
(or Back) Panel for Additional Precautionary Statements" is
required on the front panel for all products, unless all
required precautionary statements appear on the front panel.
[40 CFR 162.10(h)(l)(iii)]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING - The
precautionary statements listed below must appear together
on the label under the heading "PRECAUTIONARY STATEMENTS."
The preferred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the three hazard warning statements must be headed by the
appropriate hazard title. [40 CFR 162.10(h)(2)].
91
-------
SUMMARY-3
Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a
hazard exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard, the
route(s) of exposure and the precautions to be taken to avoid
accident, injury or damage. [40 CFR 162.10(h)(2)(i)]
Item 8B. ENVIRONMENTAL HAZARD - Where a hazard exists to
non-target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. [40 CFR 162.10(h)(2)(ii)]
Item 8C. PHYSICAL OR CHEMICAL HAZARD - FLAMMABILITY
Precautionary statements relating to flammability of a product
are required to appear on the label if it meets the criteria
in the PHYS/CHEM Labeling Appendix. The requirement is
based on the results of the flashpoint determinations and
flame extension tests required to be submitted for all products.
These statements are to be located in the side/back panel
precautionary statements section, preceded by the heading
"Physical/Chemical Hazards." Note that no signal word is
used in conjunction with the flammability statements.
Item 9A. RESTRICTED USE CLASSIFICATION - FIFRA sec. 3(d)
requires that all pesticide formulations/uses be classified
for either general or restricted use. Products classified
for restricted use may be limited to use by certified applicators
or persons under their direct supervision (or may be subject
to other restrictions that may be imposed by regulation).
In the Registration Standard, the Agency has (1) indicated
certain formulations/uses are to be restricted (Section IV
indicates why the product has been classified for restricted
use); or (2) reserved any classification decision until
appropriate data are submitted.
The Regulatory Position and Rationale states whether
products containing this active ingredient are classified
for restricted use. If they are restricted the draft label(s)
submitted to the Agency as part of your application must
reflect this determination (see below).
If you do not believe that your product should be classified
for restricted use, you must submit any information and
rationale with your application for reregistration. During
the Agency's review of your application, your proposed classi-
fication determination will be evaluated in accordance with
the provisions of 40 CFR 162.11(c). You will be notified of
the Agency's classification decision.
-------
SUMMARY-4
Classification Labeling Requirements
If your product has been classified for restricted use,
the following label requirements apply:
1. All uses restricted.
a. The statement "Restricted Use Pesticide" must
appear at the top of the front panel of the label. The
statement must be set in type of the same minimum size
as required for human hazard signal word (see table in 40
CFR 162.10(h)(l)(iv)
b. Directly below this statement on the front panel,
a summary statement of the terms of restriction must
appear (including the reasons for restriction if specified
in Section I). If use is restricted to certified applicators,
the following statement is required: "For retail sale
to and use only by Certified Applicators or persons
under their direct supervision and only for those uses
covered by the Certified Applicator's Certification."
2. Some but not all uses restricted. If the Regulatory
Position and Rationale states that some uses are classified
for restricted use, and some are unclassified, several courses
of action are available:
a. You may label the product for Restricted use.
If you do so, you may include on the label uses that
are unrestricted, but you may not distinguish them
on the label as being unrestricted.
b. You may delete all restricted uses from your
label and submit draft labeling bearing only unrestricted
uses.
c. You may "split" your registration, i.e., register
two separate products with identical formulations, one
bearing only unrestricted uses, and the other bearing
restricted uses. To do so, submit two applications for
reregistration, each containing all forms and necessary
labels. Both applications should be submitted simul-
taneously. Note that the products will be assigned
separate registration numbers.
Item 9B. MISUSE STATEMENT - All products must bear the
misuse statement, "It is a violation of Federal law to use
this product in a manner inconsistent with its labeling."
This statement appears at the beginning of the directions
for use, directly beneath the heading of that section.
-------
SUMMARY-5
Item 10A. REENTRY STATEMENT - If a reentry interval
has been established by the Agency, it must be included on
the label. Additional worker protection statements may be
required in accordance with PR Notice 83-2, March 29, 1983.
Item 10B. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage and disposal statements. These
statements are developed for specific containers, sizes, and
chemical content. These instructions must be grouped and
appear under the heading "Storage and Disposal" in the directions
for use. This heading must be set in the same type sizes as
required for the child hazard warning. Refer to Appendix II,
STOR, PEST/DIS, and CONT/DIS to determine the storage and
disposal instructions appropriate for your products.
Item IOC. DIRECTIONS FOR USE - Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate to
protect the public from fraud and from personal injury and to
prevent unreasonable adverse effects on the environment.
[40 CFR 162.10]
COLLATERAL LABELING
Bulletins, leaflets, circulars, brochures, data sheets,
flyers, or other written or graphic printed matter which is
referred to on the label or which is to accompany the product
are termed collateral labeling. Such labeling may not bear
claims or representations that differ in substance from those
accepted in connection with registration of the product. It
should be made part of the response to this notice and submitted
for review.
-------
SUMMARY-6
LABELING REQUIREMENTS OF THE FIFRA, AS AMENDED
ITEM
1
2
. 3
4
5
6A
6B
7
7A
7B
LABEL ELEMENT
Product name
Company name
and address
Net contents
EPA Reg. No.
EPA Eat. No.
Ingredients
statement
Pounds /gal Ion
statement
Front panel
precautionary
statements
Keep Out of Reach
of Children
(Child hazard
warning)
Signal word
APPLICABILITY
OF REQUIREMENT
All products
All products
All products
All products
All products
All products
Liquid products
where dosage
given as Ibs.
ai/unit area
All products
All products
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
None
None
None
None
Front panel
Front panel
Front panel
Front panel
Front panel
PREFERRED
Center front
j>anel
Bottom front
panel or end
of label text
Bottom front
panel or end
of label text
Front panel
Front panel,
immediately
before or
following
Reg. No.
Immediately
following
product name
Directly below
the main
ingredients
statement
Above signal
word
Immediately
below child
hazard
warning
COMMENTS
If registrant is not the producer, must
be qualified by "Packed for . . . , "
"Distributed by. . .," etc.
May be in metric units in addition to
U.S. units
Must be in similar type size and run
parallel to other type.
May appear on the container instead of
the label.
Text must run parallel with other text
on the panel.
All front panel precautionary statements
must be grouped together, preferably
blocked.
Note type size requirements.
Note type size requirements.
95
-------
SUMMARY-7
ITEM
70
7D
7E
8
!
!
i
8A !
|
j
8B j
l LABEL ELEMENT
Skull & cross-
bones and word
POISON (In red)
Statement of
Practical
Treatment or
First Aid
Referral
statement
Side/back panel
precautionary
statements
Hazards to
humans and
domestic
animals
Environmental
hazards
APPLICABILITY
OP REQUIREMENT
All products
which are Cat-
egory I based
on oral, der-
mal, or inhala-
tion toxicity
All products
in Categories
I, II, and III
All products
where pre-
cautionary
labeling
appears on
other than
front panel.
All products
All products
in Categories -
I, II, and III
All products
PLACEMENT ON LABEL
REQUIRED
Front panel
Category I:
Front panel
unless refer-
ral statement
is used.
Others:
Grouped with
side panel
precautionary
statements .
Front panel
None
None
None
PHEb'ifiHftED
Both in close
proximity to
signal word
Front panel
for all.
Top or side
of back panel
preceding
directions
for use
Same as above
Same as above
COMMENTS
'
Must be grouped under the headings in
8A, 8B, and 8C; preferably blocked.
fi
Must be preceded by appropriate signal
word.
Environmental hazards Include bee
caution where applicable.
96
-------
SUMMARY-8
ITEM
8c
9A
9B
10A
10B
IOC
LABEL ELEMENT
Physical OP
chemical
hazards
Restricted
block
Misuse
statement
Reentry
statement
Storage and
disposal block
Directions
for use
APPLICABILITY .
OP REQUIREMENT
All pressurized
products, others
with flash
points under
150°P
All restricted
products
All products
PR Notice 83-2
or as determined
by the Agency
All products
All products
PLACEMENT ON LABEL
HEyUlKEU
None
Top center
of front
panel
Inmedlately
following
heading of
directions
for use
In the
directions
for use
In the
directions
for use
None
PKlSKliKRED
Same as above
Preferably
blocked
Immediately
after misuse
statement
Inmedlately
before
specific
directions
for use or
at the end of
directions
for use
None
COMMENTS
Refer to Appendix II guide
PHYS/CHEM
Includes a statement of the terms of
restriction. The words "RESTRICTED USE
PESTICIDE" must be same type size as
signal word.
Required statement Is:
"It Is a violation of Federal law
to use this product In a manner
Inconsistent with Its labeling."
Must be set apart and clearly distin-
guishable from from other directions
for use.
Refer to Appendix II guides STOR,
CONT/DIS, and PEST/DIS for further
information and required statements.
May be In metric as well as U.S. units
8
97
-------
Chapter 1—Environmental Protection Agency
$162.10 Labeling requirements.
(a) General—(1) Contents of the label. Every pesticide
product shall bear a label containing the information specified by
the Act and the regulations in this Part. The contents of a
label must show clearly and prominently the following:
(i) The name, brand, or trademark under which the product is
sold as prescribed in paragraph (b) of this section;
(ii) The name and address of the producer, registrant, or
person for whom produced as prescribed in paragraph (c) of this
section;
(iii) The net contents as prescribed in paragraph (d) of this
section;
(iv) The product registration number as prescribed in paragraph
(e) of this section;
(v) The producing establishment number as prescribed in para-
graph (f) of this section;
(vi) An ingredient statement as prescribed in paragraph (g) of
this section;
(vii) Warning or precautionary statements as prescribed in
paragraph (h) of this section;
(viii) The directions for use as prescribed in paragraph (i)
of this section; and
(ix) The use classification(s) as prescribed in paragraph (j)
of this section.
(2) Prominence and legibility, (i) All words, statements,
graphic representations, designs or other information required on
the labeling by the Act or the regulations in this part must be
clearly legible to a person with normal vision, and must be placed
with such conspicuousness (as compared with other words, state-
ments, designs, or graphic matter on the labeling) and expressed
in such terms as to render it likely to be read and understood
by the ordinary individual under customary conditions of purchase
and use.
(ii) All required label text must:
(A) Be set in 6-point or larger type;
(B) Appear on a clear contrasting background; and
(C) Not be obscured or crowded. :
(3) Language to be used. All required label or labeling text
shall appear in the English language. However, the Agency may
require or the applicant may propose additional text in other
languages as is considered necessary to protect the public. When
additional text in another language is necessary, all labeling
requirements will be applied equally to both the English and
other-language versipns of the labeling.
(4) Placement of Label—(i) General. The label shall appear
on or be securely attached to the immediate container of the
98
-------
pesticide product. For purposes of this Section, and the mis-
branding provisions of the Act, "securely attached" shall mean
that a label can reasonably be expected to remain affixed during
the foreseeable conditions and period of use. If the immediate
container is enclosed within a wrapper or outside container
through which the label cannot be clearly read, the label must
also be securely attached to such outside wrapper or container,
if it is a part of the package as customarily distributed or
sold.
(ii) Tank cars and other bulk containers — (A) Transportation.
While a pesticide product is in transit, the appropriate
provisions of 49 CFR Parts 170-189, concerning the transportation
of hazardous materials, and specifically those provisions con-
cerning the labeling, marking and placarding of hazardous materials
and the vehicles carrying them, define the basic Federal require-
ments. In addition, when any registered pesticide product is
transported in a tank car, tank truck or other mobile or portable
bulk container, a copy of the accepted label must be attached to
the shipping papers, and left with the consignee at the time of
delivery.
(B) Storage. When pesticide products are stored in bulk
containers, whether mobile or stationary, which remain in the
custody of the user, a copy of the label of labeling, including
all appropriate directions for use, shall be securely attached to
the container in the immediate vicinity of the discharge control
valve.
(5) False or misleading statements. Pursuant to section
2(q)(l)(A) of the Act, a pesticide or a device declared subject
to the Act pursuant to § 162.15, is misbranded if its labeling is
false or misleading in any particular including both pesticidal
and non-pesticidal claims. Examples of statements or representations
in the labeling which constitute misbranding include:
(i) A false or misleading statement concerning the composition
of the product;
(ii) A false or misleading statement concerning the effectiveness
of the product as a pesticide or device;
(iii) A false or misleading statement about the value of the
product for purposes other than as a pesticide or device;
(iv) A false or misleading comparison with other pesticides or
devices;. C
(v) Any statement directly or indirectly .implying that the
pesticide or device is recommended or endorsed by any agency of
the Federal Government;
(vi) The name of a pesticide which contains two or more
principal active ingredients if the name suggests one or more but
not all such principal active ingredients even though the names
of the other ingredients are stated elsewhere in the labeling;
(vii) A true statement used in such a way as to give a false
or misleading impression .to the purchaser; ,
(viii) Label disclaimers which negate or detract from labeling
statements required under the Act and these regulations;
99
-------
(ix) Claims as to the safety of the pesticide or its ingredients,
including statements such as "safe," "nonpoisonous," "noninjurious,"
"harmless" or "nontoxic to humans and pets" with or without- such
a qualifying phrase as "when used as directed"; and
(x) Non-numerical and/or comparative statements on the safety
of the product, including but not limited to:
(A) "Contains all natural ingredients";
(B) "Among the least toxic chemicals known"
(C) "Pollution approved"
(6) Final printed labeling. (i) Except as provided in
paragraph (a)(6)(ii) of this section, final printed labeling must
be submitted and accepted prior to registration. However, final
printed labeling need not be submitted until draft label texts
have been provisionally accepted by the Agency.
(ii) Clearly legible reproductions or photo reductions will be
accepted for unusual labels such as those silk-screened directly
onto glass or metal containers or large bag or drum labels. Such
reproductions must be of microfilm reproduction quality.
(b) Name, brand, or trademark. (1) The name, brand, or
trademark under which the pesticide product is sold shall appear
on the front panel of the label.
(2) No name, brand, or trademark may appear on the label which:
(i) Is false or misleading, or
(ii) Has not been approved by the Administrator through
registration or supplemental registration as an additional name
pursuant to S 162.6(b)(4).
(c) Name and address of producer, registrant, or person for
whom produced. An unqualified name and address given on the
label shall be considered as the name and address of the producer.
If the registrant's name appears on the label and the registrant
is not the producer, or if the name of the person for whom the
pestrcide was produced appears on the label, it must be qualified
by appropriate wording such as "Packed for ***," "Distributed by
***," or "Sold by ***" to show that the name is not that of the
producer.
(d) Net weight or measure of contents. (1) The net weight or
measure of content shall be exclusive of wrappers or other
materials and shall be the average content_unless explicitly
stated as a minimum quantity. ~ ~ "
(2) If the pesticide is a liquid, the ne£content statement
shall be'in terms of liquid measure at 68°F .(20°C) and shall be
expressed in conventional American units of fluid ounces, pints,
quarts, and gallons.
(3) If the pesticide is solid or semisolid, viscous or
pressurized, or is a mixture of liquid and solid, the net content
statement shall be in terms of weight expressed as avoirdupois
pounds and ounces.
(4) In all cases, net content shall be stated in terms of the
largest suitable units, i.e., *1 pound 10 o'unces'" rather than
"26 ounces."
100
-------
(5) In addition to the required units specified, net content
may be expressed in metric units.
(6) Variation above minimum content or around an average is
permissible only to the extent that it represents deviation
unavoidable in good manufacturing practice. Variation below a
stated minimum is not permitted. In no case shall the average
content of the packages in a shipment fall below the stated
average content.
(e) Product registration number. The registration number
assigned to the pesticide product at the time of registration
shall appear on the label, preceded by the phrase "EPA Registration
No.,".or the phrase "EPA Reg. No." The registration number shall
be set in type of a size and style similar to other print on that
part of the label on which it appears and shall run parallel to
it. The registration number and the required identifying phrase
shall not appear in such a manner as to suggest or imply
recommendation or endorsement of the product by the Agency.
(f) Producing establishments registration number. The producing
establishment registration number preceded by the phrase "EPA
Est.", of the final establishment at which the product was produced
may appear in any suitable location on the label or immediate
container. It must appear on the wrapper or outside container of
the package if the EPA establishment registration number on the
immediate container cannot be clearly read through such wrapper
or container.
(g) Ingredient statement—(1) General. The label of each
pesticide product must bear a statement which contains the name
and percentage by weight of each active ingredient, the total
percentage by weight of all inert ingredients; and if the pesticide
contains arsenic in any form, a statement of the percentages of
total and water-soluble arsenic calculated as elemental arsenic.
The active ingredients must be designated by the term "active
Ingredients" and the inert ingredients by the term "inert
ingredients," or the singular forms of these terms when appropriate.
Both terms shall be in the same type size, be aligned to the same
margin and be equally prominent. The statement "Inert Ingredients,
none" is not required for pesticides which contain 100 percent
active ingredients. Unless the ingredient statement is a complete
analysis of the pesticide, the terra "analysis" shall not be used
as a heading for the ingredient statement. ~
(2) "Position of ingredient statement, (i) The ingredient
statement is normally required on the front'panel of the label.
If there is an outside container or wrapper through which the
ingredient statement cannot be clearly read, the ingredient
statement must also appear on such outside container or wrapper.
If the size or form of the package makes it impracticable to place
the ingredient statement on the front panel of the label, permission
may be granted for the ingredient statement to appear elsewhere.
(ii) The text "of the ingredient statement must run parallel
with other text on the panel on which it appears, and must be
clearly distinguishable from and must not be placed in the body
of other text.
1C!
-------
(3) Names to be used in ingredient statement. The name used
for each ingredient shall be the accepted common name, if there
is one, followed by the chemical name. The common name may be
used alone only if it is well known. If no common name has been
established, the chemical name alone shall be used. In no case
will the use of a trademark or proprietary name be permitted unless
such name has been accepted as a common name by the Administrator
under the authority of Section 25(c)(6).
(4) Statements of percentages. The percentages of ingredients
shall be stated in terms of weight-to-weight. The sum of per-
centages of the active and the inert ingredients shall be 100.
Percentages shall not be expressed by a range of values such as
"22-25%." If the uses of the pesticide product are expressed as
weight of active ingredient per unit area, a statement of the
weight of active ingredient per unit volume of the pesticide
formulation shall also appear in the ingredient statement.
(5) Accuracy of stated percentages. The percentages given
shall be.as precise as possible reflecting good manufacturing
practice. If there may be unavoidable variation between manu-
facturing batches, the value stated for each active ingredient
shall be the lowest percentage which may be present.
(6) Deterioration. Pesticides which change in chemical
composition significantly must meet the following labeling re-
quirements:
(i) In cases where it is determined that a pesticide formulation
changes chemical composition significantly, the product must bear
the following statement in a prominent position on the label: "Not
for sale or use after [date]."
(ii) The product must meet all label claims up to the expiration
time indicated on the label.
(7) Inert ingredients. The Administrator may require the name
of any inert ingredient(s) to be listed in the ingredient statement
if he determines that such ingredient(s) may pose a hazard to man
or the environment.
(h) Warnings and precautionary statements. Required warnings
and precautionary statements concerning the general areas of
toxicological hazard including hazard to children, environmental
hazard, and physical or chemical hazard fall into two groups; those
required "on the front panel of the labeling and those which may
appear elsewhere. Specific requirements concerning content,
placement, type size, and.prominence are given below.
(1) Required front panel statements. With the exception of the
child hazard warning statement, the text required on the front
panel of the label is determined by the Toxicity Category of the
pesticide. The category is assigned on the basis of the highest
hazard shown by any of the indicators in the table below:
102
-------
Hazard Indicators
Oral L0e
50
Inhalation LC
Dermal LD
,
Eye effects
Skin effects
1
Up to and
Including
50 mg/kg
Up to and
1 nc 1 ud 1 ng
.2 mg/l Her
Up to and
Including
200 mg/kg
Corrosive;
cornea 1 opacity
not reversible
within 7 days
Corrosive
Toxlclty
II
From 50 thru
500 mg/kg
From .2 thru
2 mg/Mter
From 200
thru 2000
Cornea 1 opacity
reversible
within 7 days;
Irritation
persisting for
7 days
Severe Irritation
at 72 hours
categories
III
From 500 thru
5000 mg/kg
From 2 thru
20 mg/llter
From 2,000 thru
20,000
No corneal opacity;
Irritation
reversible
within 7 days
Moderate Irritation
at 72 hours
.•
IV
Greater than
5000 mg/kg
Greater than
20 mg/l tter
Greater than
20,000
No Irritation
Mild or slight.
Irritation at
72 hours
(i) Human hazard signal word.—(A) Toxicity Category I. All
pesticide products meeting the criteria of Toxicity Category I
shall bear on the front panel the signal word "Danger." In
addition if the product was assigned to Toxicity Category I on
the basis of its oral, inhalation or dermal toxicity (as distinct
from skin and eye local effects) the word ^Poison" shall appear
in red..on a background of distinctly contrasting color and the
skull and crossbones shall appear in immediate proximity to the
word "poison."
(B) Toxicity Category II. All pesticide products meeting the
criteria of Toxicity Category II shall bear on the front panel*
the signal word "Warning."
(C) Toxicity Category III. All pesticide products meeting the
criteria of Toxicity Category III shall bear on the front panel
the signal word "Cautioih
(D) Toxicity Category IV.
All pesticide products meeting the
criteria of Toxicity Category IV shall bear on the front panel
the signal word "Caution."
103
-------
(E) Use of signal words. Use of any signal word(s) associated
with a higher Toxicity Category is not permitted except when the
Agency determines that such labeling is necessary to prevent
unreasonable adverse effects on man or the environment. In no
case shall more than one human hazard signal word appear on the
front panel of a label.
(ii) Child hazard warning. Every pesticide product label shall
bear on the front panel the statement "keep out of reach of
children." Only in cases where the likelihood of contact with
children during distribution, marketing, storage or use is
demonstrated by the applicant to be extremely remote, or if the
nature.of the pesticide is such that it is approved for use on
infants or small children, may the Administrator waive this
requirement.
(iii) Statement of practical treatment—(A) Toxicity
Category I. A statement of practical treatment (first aid or
other) shall appear on the front panel of the label of all
pesticides falling into Toxicity Category I on the basis of oral,
inhalation or dermal toxicity. The Agency may, however, permit
reasonable variations in the placement of the statement of
practical treatment is some reference such as "See statement of
practical treatment on back panel" appears on the front panel
near the word "Poison" and the skull and crossbones.
(B) Other toxicity categories. The statement of practical
treatment is not required on the front panel except as described
in paragraph (h)(1)(iii)(A) of this-section. The applicant may,
however, include such a front panel statement at his option.
Statements of practical treatment are, however, required elsewhere
on the label in accord with paragraph (h)(2> of this section if
they do not appear on the front panel.
(iv) Placement and prominence. All the required front panel
warning statements shall be grouped together on the label, and
shall appear with sufficient prominence relative to other front
panel text and graphic material to make them unlikely to be over-
looked under customary conditions of purchase and use. The
following table shows the minimum type size requirements for the
front panel warning statements on various sizes of labels:
Size of label front panel
in square inches
Over 30
Points
Requ i'red
signal .word,
all capitals
6
10
12
14
18
"Keep out
of reach of
Children"
6
6
8
10
12
104
-------
(2) Other required warnings and precautionary statements. The
warnings and precautionary statements as required below shall appear
together on the label under the general heading "Precautionary
Statements" and under appropriate subheadings of "Hazard to Humans
and Domestic Animals," "Environmental Hazard" and "Physical pr
Chemical Hazard."
(i) Hazard to humans and domestic animals. (A) Where a hazard
exists to humans or domestic animals, precautionary statements
are required indicating the particular hazard, the route(s) of
exposure and the precautions to be taken to avoid accident, injury
or damage. The precautionary paragraph shall be immediately
preceded by the appropriate hazard signal word.
(B) The following table depicts typical precautionary statements.
These statements must be modified or expanded to reflect specific
hazards.
Toxlclty
category
Precautionary statements by toxlclty category
Oral. Inhalation, or dermal toxlclty
Skin and eye local effects
I . .
II . .
Ill . .
IV . .
Fatal (poisonous) If swallowed (Inhaled or
absorbed through skin). Do not breathe
vapor (dust] or spray mist). Do not get
In eyes, on skin, or on clothing (Front
panel statement of practical treatment
required.).
May be fatal If swallowed (Inhaled or
absorbed through the skin). Do not breathe
vapors (dust or spray mist). Do not get In
eyes, on skin, or on clothing. (Appropriate
first aid statements required.].
Harmful If swallowed (Inhaled or absorbed
through the sklnl. Avoid breathing vapors
(dust or spray Mist]. Avoid contact with
skin (eyes or clothing). (Appropriate
first aid statement required.).
(No precautionary statements required.).
Corrosive, causes eye and skin damage lor
skin Irritation). Do not get In eyes, on
skin, or on clothing. Wear goggles or face
shield and rubber gloves when handling.
Harmful or fatal If swallowed.
(Appropriate first aid statement required.)
Causes eye land skin) Irritation. Do not
get In eyes, on skin, or on clothing.
Harmful It swallowed. (Appropriate first
aid statement required.).
Avoid contact with skin, eyes or clothing.
In case of contact Immediately flush
eyes OF skin with plenty of water. Get
•tedleaf attention If Irritation persists.
(No precautionary statements required.).
(ii) Environmental hazards. Where a hazard exists to non-
target organisms excluding humans and domestic animals, precautionary
statements are required stating the nature of the hazard and the
appropriate precautions to avoid potential accident, injury or _ _
105
-------
damage. Examples of the hazard statements and the circumstances
under which they are required follow:
(A) If a pesticide intended for outdoor use contains an active
ingredient with a mammalian acute oral LD5Q of 100 or less, the
statement "This Pesticide is Toxic to Wildlife" is required.
(B) If a pesticide intended for outdoor use contains an active
ingredient with a fish acute LC$Q of 1 ppm or less, the statement
"This Pesticide is Toxic to Fish" is required.
(C) If a pesticide intended for outdoor use contains an active
ingredient with an avian acute oral LD$Q of 100 mg/kg or less, or
a subacute dietary LCso of 500 ppm or less, the statement "This
Pesticide is Toxic to Wildlife" is required.
(D) If either accident history or field studies demonstrate
that use of the pesticide may result in fatality to birds, fish
or mammals, the statement "This pesticide is extremely toxic to
wildlife (fish)" is required.
(E) For uses involving foliar application to agricultural
crops, forests, or shade trees, or for mosquito abatement
treatments, pesticides toxic to pollinating insects must bear
appropriate label cautions.
(F) For all outdoor uses other than aquatic applications the
label must bear the caution "Keep out of lakes, ponds or streams.
Do not contaminate water by cleaning of equipment or disposal of
wastes."
(iii) Physical or chemical hazards. Warning statements on the
flammability or explosive characteristics of the pesticide are
required as follows:
Flash point
Required text
(A) PRESSURIZED CONTAINERS
Flash point at or below 20*F; If there Is a
flashback at any valve opening.
Flash point above 20*F and not over 80*F or If
the flame extension Is more than 18 In. long
at a distance of 6 In. from the flame.
Extremely flammable. Contents under pressure.
Keep away from fire, sparks, and heated
surfaces. Do not puncture or Incinerate
container. Exposure to temperatures above
130*F may cause bursting.
Flammable. Contents under pressure. Keep away
from heat^ sparks, and open flame. Do not
puncture or Incinerate container. Exposure to
temperature* above 130*F may cause bursting.
Contents under pressure. Do not use or store
near heat or open flame. Do not puncturfe or
Incinerate container. Exposure to tempera-
tures above 150*F may cause bursting.
(B) NONPRESSURIZED CONTAINERS
<
Extremely flammable. Keep away from fire,
sparks, and heated surfaces.
Flammable. Keep away from heat and open flame.
Do not use or store near heat or open flame.
106
-------
(i) Directions for Use—(1) General requirements—(i) Adequacy
and clarity of directions. Directions for use must be stated m
terms which can be easily read and understood by the average
person likely to use or to supervise the use of the pesticide.
When followed, directions must be adequate to protect the public
from fraud and from personal injury and to prevent unreasonable
adverse effects on the environment.
(ii) Placement of directions for use. Directions may appear
on any portion of the label provided that they are conspicuous
enough to be easily read by the user of the pesticide product.
Directions for use may appear on printed or graphic matter which
accompanies the pesticide provided that:
(A) If required by the Agency, such printed or graphic matter
is securely attached to each package of the pesticide, or placed
within the outside wrapper or bag;
(B) The label bears a reference to the directions for use in
accompanying leaflets or circulars, such as "See directions in
the enclosed circular." and
(C) The Administrator determines that it is not necessary for
such directions to appear on the label.
(iii) Exceptions to requirement for direction for use—(A)
Detailed directions for use may be omitted from labeling of
pesticides which are intended for use only by manufacturers of
products other than pesticide products in their regular manu-
facturing processes, provided that:
(^) The label clearly shows that the product is intended for
use only in manufacturing processes and specifies the type(s) of
products involved.
(2) Adequate information such as technical data sheets or
bulletins, is available to the trade specifying the type of
product involved and its proper use in manufacturing processes;
(^.). The product will not come into the hands of the general
public except after incorporation into finished products; and
(4) The Administrator determines that such directions are not
necessary to prevent unreasonable adverse effects on man or the
environment.
(B) Detailed directions for use may be omitted from the labeling
of pesticide products for which sale is limited to physicians,
veterinarians, or druggists, provided that:
(JO The label clearly states that the product is for use only
by physicians or veterinarians;
(2) The Administrator determines that such directions are not
necessary to prevent unreasonable adverse effects on man or the
environment; and
(^) The product is also a drug and regulated under the provisions
of the Federal Food, Drug and Cosmetic Act.
(C) Detailed directions for use may be omitted from the labeling
of pesticide products which are intended for use only by formulators
in preparing pesticides for sale to the public, provided that:
(1.) There is information readily available to the formulators
on the composition, toxicity, methods of use, applicable restrictions
or limitations, and effectiveness of the product for pesticide
purposes;
- ;y£*Z'
107
-------
(2) The label clearly states that the product is intended for
use only in manufacturing, formulating, mixing, or repacking for
use as a pesticide and specifies the type(s) of pesticide products
involved;
(_3) The product as finally manufactured, formulated, mixed, or
repackaged is registered; and
(_4_) The Administrator determines that such directions are not
necessary to prevent unreasonable adverse effects on man or the
environment.
(2) Contents of Directions for Use. The directions for use
shall include the following, under the headings "Directions for
Use": •
(i) The statement of use classification as prescribed in
162.10(j) immediately under the heading "Directions for Use."
(ii) Immediately below the statement of use classification,
the statement "It is a violation of Federal law to use this
product in a manner inconsistent with its labeling."
(iii) The site(s) of application, as for example the crops,
animals, areas, or objects to be treated.
(iv) The target pest(s) associated with each site.
(v) The dosage rate associated with each site and pest.
(vi) The method of application, including instructions for
dilution, if required, and type(s) of application apparatus or
equipment requried.
(vii) The frequency and timing of applications necessary to
obtain effective results without causing unreasonable adverse
effects on the environment.
(viii) Specific limitations on reentry to areas where the
pesticide has been applied, meeting the requirements concerning
reentry provided by 40 CFR Part 170.
(ix) Specific directions concerning the storage and disposal
of the pesticide and its container, meeting the requirements of
40 CFR Part 165. These instructions shall be grouped and appear
under the heading "Storage and Disposal." This heading must be
set in type of the same minimum sizes as required for the child
hazard warning (See Table in § 162.10(h)(1)(iv).)
(x) Any limitations or restrictions on use required to prevent
unreasonable adverse effects, such as:
(A) Required intervals between application and harvest of food
or feed crops.
(B) Rotational crop restrictions.
(C) Warnings as required against use on certain crops, animals,
objects, or in or adjacent to certain areas.
(D) [Reserved]
(E) For restricted use pesticides, a statement that the
pesticide may be applied under the direct supervision of a
certified applicator who is not physically present at the site of
application but nonetheless available to the person applying the
pesticide, unless the Agency has determined that the pesticide
may only be applied under the direct supervision of a certified
applicator who is physically present.
108
-------
(F) Other pertinent information which the Administrator
determines to be necessary for the protection of man and the
environment.
(j) Statement of Use Classification. By October 22, 1976, all
pesticide products must bear on their labels a statement of use
classification as described in paragraphs (j)(l) and (2) of this
section. Any pesticide product for which some uses are classified
for general use and others for restricted use shall be separately
labeled according to the labeling standards set forth in this
subsection, and shall be marketed as separate products with
different registration numbers, one bearing directions only for
general use(s) and the other bearing directions for restricted
use(s) except that, if a product has both restricted use(s) and
general use(s), both of these uses may appear on a product labeled
for restricted use. Such products shall be subject to the
provisions of § 162.10(j)(2).
(1) General Use Classification. Pesticide products bearing
directions for use(s) classified general shall be labeled with
the exact words "General Classification" immediately below the
heading "Directions for Use." And reference to the general
classification that suggests or implies that the general utility
of the pesticide extends beyond those purposes and uses contained
in the Directions for Use will be considered a false or misleading
statement under the statutory definitions of misbranding.
(2) Restricted Use Classification. Pesticide products bearing
direction for use(s) classified restricted shall bear statements
of restricted use classification on the front panel as described
below:
(i) Front panel statement of restricted use classification.
(A) At the top of the front panel of the label, set in type of
the same minimum sizes as required for human hazard signal words
(see table in § 162.10(h)(1)(iv)), and appearing with sufficient
prominence relative to other text and graphic material on the
front panel to make it unlikely to be overlooked under customary
conditions of purchase and use, the statement "Restricted Use
Pesticide" shall appear.
(B) Directly below this statement on the front panel, a summary
statement of the terms of restriction imposed as a precondition
to registration shall appear. If use is restricted to certified
applicators, the following statement is required: "For retail
sale to and use only by Certified Applicators or persons under
their direct supervision and only for those uses covered by the
Certified Applicator's certification." If, however, other
regulatory restrictions are imposed, the Administrator will define
the appropriate wording for the terms of restriction by regulation.
(k) Advertising. [Reserved]
(40 FR 28268, July 3, 197S; 40 FR 32329, Aug. 1, 1975; 40 FR
38571, Aug. 21, 1975, as amended at 43 FR 5786, Feb. 9, 1978]
109
-------
Criteria
PHYS/CHEM-1
PHYSICAL/CHEMICAL HAZARDS
««
Required Label Statement
I. Pressurized Containers
A.
Flashpoint at or below
20°F; or if there is a
flashback at any valve
opening.
B
Flashpoint above 20°F
and not over 80°F; or
if the flame extension
is more than 18 inches
long at a distance of
6 inches from the
valve opening.
All Other Pressurized
Containers
II. Non-Pressurized Containers
A. Flashpoint at or below
20°F.
B. Flashpoint above 20°F
and not over 80°F.
C. Flashpoint over 80°F
and not over 150°F.
D. Flashpoint above
150°F.
Extremely flammable.
Contents under pressure.
Keep away from fire, sparks,
and heated surfaces. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame. Do
not puncture or incinerate
container. Exposure to
temperatures above 130°F
may c'ause bursting.
Contents under pressure.
Do not use or store near
heat or open flame. Do not
puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Extremely flammable. Keep
away from fire, sparks, and
heated surfaces.
Flammable. Keep away from
heat and open flame.
Do not use or store near
heat and open flame.
None required.
1 10
-------
STOR-1
STORAGE INSTRUCTIONS FOR PESTICIDES
Heading;
All products are required to bear specific label instructions
about storage and disposal. Storage and disposal instructions
must be grouped together in the directions for use portion of
the label under the heading STORAGE AND DISPOSAL. Products
intended solely for domestic use need not include the heading
"STORAGE AND DISPOSAL."
Storage Instructions;
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed.
Each registrant must develop his own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, heat, sunlight,
friction, or contaminating substances or media.
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
while opening or closing container.
4. Instructions on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been
spilled, and precautions to minimize exposure if damage occurs
5. General precautions concerning locked storage, storage in
original container only, and separation of pesticides
during storage to prevent cross-contamination of other
pesticides, fertilizer, food, and feed.
6. General storage instructions for household products should
emphasize storage in original container and placement in
locked storage areas.
111
-------
PEST/DIS-1
PESTICIDE DISPOSAL INSTRUCTIONS
The label of all products, except those intended solely for domestic'
use, must bear explicit instructions about pesticide disposal. The
statements listed below contain the exact wording that must appear on
the label of these products:
1. The labels of all products, except domestic use, must contain the
statement, "Do not contaminate water, food, or feed by storage or disposal."
2. Except those products intended solely for domestic use, the labels
of all products that contain active ingredients that are Acute Hazardous
Wastes (see list in this Appendix) or are assigned to Toxicity Category
I on the basis of oral or dermal toxicity, skin or eye irritation potential,
or Toxicity Category I or II on the basis of acute inhalation toxicity
must bear the following pesticide disposal statement:
"Pesticide wastes are acutely hazardous. Improper disposal of
.excess pesticide, spray mixture, or rinsate is a violation of Federal
Law. if these wastes cannot be disposed of by use according to
label instructions, contact your State Pesticide or Environmental
Control Agency, or the Hazardous Waste representative at the nearest
EPA Regional Office for guidance."
3. The labels of all products, except those intended for domestic use,
containing active or inert ingredients that are Toxic Hazardous Wastes
(see list in this Appendix) or meet any of the criteria in 40 CFR 261,
Subpart C for a hazardous waste must bear the following pesticide disposal
statement:
"Pesticide wastes are toxic. Improper disposal of excess pesticide,
spray mixture, or rinsate is a violation of Federal Law. If these
wastes cannot be disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control Agency, or the
Hazardous Waste representative at the nearest EPA Regional Office
for guidance."
4. Labels for all-other products, except those intended for domestic
use, must bear the following pesticide disposal statement:
"Wastes resulting from the use of this product may be disposed of on
site or at an approved waste disposal facility."
5. Products intended for domestic use only must bear the following
disposal statement: "Securely wrap original container in several layers
of newspaper and discard in trash."
112
-------
PEST/DIS-2
P003
P070
P004
POOS
P006
POOS
P010
P011
P012
P021
P022
P024
P030
P031
P037
P039
P040
107-13-1
116-06-3
309-00-2
107-18-6
1302-45-0
504-24-5
7778-39-4
1303-28-2
1327-53-3
502-01-8
75-15-0
106-47-8
506-77-4
60-57-1
298-04-4
297-97-2
PESTICIDE ACTIVE INGREDIENTS THAT ARE ACUTE "HAZARDOUS WASTES
I. PESTICIDES ON THE "E" LIST (with RCRA f and CAS I
[40 CFR 261.33(e))
Acrolein
Aldicarb
Aldrin
Allyl alcohol
Aluminum phosphide
4-Aminopyridine (Avitrol)
Arsenic acid
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroani1ine
Cyanides (soluble cyanide salts
not otherwise specified)
Cyanogen chloride
Dieldrin
O,0-Diethyl S-[2-ethylthio)ethyl]
phosphorodithioate (disulfoton)
0,0-Diethyl Opyrazinyl
phosphorothioate (Zinophos®)
Dimethoate
0,0-Dimethyl O-p-nitrophenyl
phosphorothioate (methyl parathion)
4,6-Dinitro-c—cresol and salts
4,6-Dinitro-o-cyclohexylphenol
Dinoseb
Endosulfan
Endothall
Endrin
Famphur
Fluoroacetamide
Heptachlor
Hexachlorohexahydro-exo,exo-
dimethanonaphthalene (Isodrin)
Hydrocyanic acid
Methonyl
alpha-Naphthylthiourea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramide
(OMPA, schradan)
Parathion
Phenylmercuric acetate (PMA)
Phorate
Potassium cyanide
Propargyl alcohol
Sodium azide
Sodium cyanide
Sodium fluoroacetate
P044
P071
P047
P034
P020
P050
P088
P051
P097
P057
P059
P069
P063
P066
P072
P075
P085
P089
P092
P094
P098
P102
P105
P106
P058
60-51-5
298-00-0
534-52-1
131-89-5
88-85-7
115-29-7
129-67-9
72-20-8
52-85-7
640-19-7
76-48-8
465-73-6
74-90-8
16752-77-5
86-88-41
54-11-5
152-16-9
56-38-2
62-38-4
298-02-2
151-50-8
107-19-7
26628-22-8
143-33-9
62-74-8
1)3
-------
PEST/DIS-3
Strychnine and salts P108 57-24-9
60-41-3
O,O,0,Q-Tetraethyl P109 3689-24-5
dithiopyrophosphate (sulfotepp)
Tetraethyl pyrophosphate Pill 107-49-3
Thallium sulfate Pi15 7446-18-6
Thiofanox P045 39196-18-4
Toxaphene P123 8001-35-2
Warfarin (>0.3%) P001 81-81-2
Zinc phosphide (>10%) P122 1314-84-7
50 ACTIVES
II. PESTICIDES DERIVED FROM TRI-, TETRA-, AND PENTACHLOROPHENOLS
[40 CFR 261.31]
2-Chloroethyl 2-(2,4,6-trichloro- F027 5324-22-1
phenoxy) ethyl ether
Dehydroabietylamnonium F027 35109-57-0
pentachlorophenoxide
Erbon F027 136-25-4
O-ethyl O( 2,4,5-trichlorophenyl)
ethylphosphonothioate F027 327-98-0
2,2'-Methylenebis F027 70-30-4
(3,4,6-trichlorcphenol)
(Hexachlorophene)
—Potassiun salt of F027 67923-62-0
—Sodium salt of F027 3247-34-5
—Disodium salt of F027 5736-15-2
Pentachlorophenol F027 87-86-5
—Potassium salt of F027 7778-73-6
—Sodium salt of F027 131-52-2
—Zinc salt of F027 2917-32-0
—Zinc salt of N-alkyl F027
(CIQ-CIS)-1r3-propanediamine
—Pentachlorophenyl laurate F027 3772-94-9
Potassium trichlorophenate (2,4,6) F027 2591-21-1
Potassium trichlorophenate (2,4,5) F027 35471-43-3
Silvex F027 93-72-1
—2-Butoxyethyl ester F027 19398-13-1
—Butoxypolypropoxypropyl ester F027 53404-07-2
—Butoxypropyl ester F027 25537-26-2
—Diethanolamine salt F027 51170-59-3
—Diisopropanolamine salt . F027 53404-09-4
—Dimethylamine salt F027 55617-85-1
—Dipropylene glycol isobutyl F027 53535-26-5
ether ester
—Ethanolamine salt F027 7374-47-2
—2-Ethylhexyfc ester F027 53404-76-5
—Isooctyl ester F027 53404-14-1
114
-------
PEST/DIS-4
—Isopropanolamine salt
—Monohydroxylaluminum salt
—Polypropoxypropyl ester
—Potassiun salt
—Propylene glycol isobutyl
ether ester
—Sodiun salt
—Triethanolamine salt
—Triethylamine salt
—Triisopropanolamine salt
—Tripropylene glycol isobutyl
ether ester
Sodium 2-(2,4,5-trichlorophenoxy)
ethyl sulfate
Tetrachlorophenols
—Alkylamine*amine salt (as in
fatty acids of coconut oil)
—Potassiun salt
—Sodium salt
2,4,5-Trichlorophenol
2/4,6-Trichlorophenol
2,4,5-Trichlorophenol salt of
2,6-bis [ (dimethylamino)methyl]
cyclohexanone
2,4,5-Trichlorophenol, sodium salt
2,4,6-Trichlorophenol, sodium salt
2,4,5-Trichlorophenoxyacetic acid
—Alkyl C-12 amine salt
—Alkyl C-13 amine salt
—Alkyl C-14 amine salt
—NfN-diethylethanolamine salt
—Diinethylamine salt
—N,N-dimethyllinoleylamine salt
—NrN-dimethyloleylamine salt
—N-oleyl-1,3-propylene
diamine salt
—Sodium salt
—Triethanolamine salt
—Triethylanine salt
—Alkyl (C3H7 - C7H9) ester
—Amyl ester
—Butoxyethoxypropyl ester .
—2-Butoxyethyl ester
—Butoxypropyl ester
—Butyl ester
—Dipropylene glycol isobutyl
ether ester
—2-Ethylhexyl ester
—Isobutyl ester
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
53404-13-0
69622-82-8
83562-66-7
2818-16-8
53466-84-5
37913-89-6
17369-89-0
53404-74-3
53404-75-4
53535-30-1
3570-61-4
25167-83-3
53535-27-6
25567-55-9
95-95-4
88-06-2
53404-83-4
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
F027
136-32-3
3784-03-0
93-79-8
53404-84-5
53404-85-6
53535-37-8
53404-86-7
6369-97-7
53404-88-9
53404-89-0
53404-87-8
13560-99-1
3813-14-7
2008-46-0
120-39-8
1928-58-1
2545-59-7
1928-48-9
93-79-8
53535-31-2
1928-47-8
4938-72-1
115
-------
PEST/DIS-5
—Isopropyl ester F027 93-78-7
—Propylene glycol isobutyl F027 53466-86-7
ether ester
—Tripropylene glycol isobutyl F027 53535-32-3
ether ester
4-(2,4,5-Trichlorophenoxy)butyric F027 93-80-1
acid [2,4,5-TB]
2-( 2,4,5-Trichlorophenoxy)ethyl F027 69633-04-1
hydrogen sulfate [2,4,5-TES]
l,4\5'-Trichloro-2'-(2,4,5- F027 69462-14-2
trichlorophenoxy)
methanesulfonanilide [Eclolan U]
116
-------
PEST/DIS-6
PESTICIDES THAT ARE TOXIC HAZARDOUS WASTES
PESTICIDES ON THE "F" LIST (with
[40 CFR 261.33(f)]
Acetone
Acrylonitrile*
Anitrole
Benzene*
Bis( 2-ethylhexyl ) phthalate
Cacodylic acid
Carbon tetrachloride*
Chloral (hydrate)
( chloroacetaldehyde )
Chlordane, technical*
Chlorobe nzene*
4-Chloro-m-cresol
Chloroform*
o-Chlorophenol
Creosote
Cresylic acid (cresols)*
Cyclohexane
Cyclohexanone
Decachlorooctahydro-1 ,3 ,4-metheno-
2H-cyclobuta [c , d) -pentalen-2-one
(Kepone, chlordecone)
1 , 2-Dibrono-3-chloropropane ( DBCP )
Dibutyl phthalate
S-2 , 3- ( Dichloroallyl di isopropyl-
thiocarbamate) (diallate,Avadex)
o-Dichlorobenzene*
p-Di chlorobe nzene*
Dichlorodifluorcme thane
(Freon 12®)
3f5-Dichloro-N-(l ,l-dimethyl-2-
propynyl) benzamide
(pronamide, Kerb*)
Dichloro diphenyl dichloroethane
(DDD)
Dichloro diphenyl trichloroethane
(DDT)
Dichloroethyl ether
2 ,4-Dichlorophenoxyacet ic ,
salts and esters (2,4-D)*
1 ,2-Dichloropropane
1,3-Dichloropropene (Telone)
Dimethyl phthalate
Epichlorohydrin
( l-chloro-2 , 3-epoxy propane )
Ethyl acetate
Ethyl 4,4'-dichlorobenzilate
(chlorobe nzilate)
RCRA ft,
U002
U009
U011
U019
U028
U136
U211
U034
U036
U037
U039
U044
U048
U051
U052
U056
U057
U142
U066
U069
U062
U070
U072
U075
U192
U060
U061
U025
U240
U083
U084
U102
U041
U112
U038
, and CAS f
67-64-1
107-13-1
61-82-5
71-43-2
117-81-7
75-60-5
56-23-5
. 302-17-0
57-74 0
108-90-7
59-50-7
67-66-3
95-57-8
8021-39-4
1319-77-3
110-82-7
108-94-1
143-50-0
96-12-8
84-74-2
2303-16-4
95-50-1
106-46-7
75-71-8
23950-58-5
72-54-8
50-29-3
1191-17-9
94-75-7
8003-19-8
542-75-6
131-11-3
106-89-8
' 141-78-6
510-15-6
*Proposed fot?^!§letion by TCLP proposal
117
-------
PEST/DIS-7
Ethylene dibromide (EDB)
Ethylene dichloride*
Ethylene oxide
Fonnaldehyde
Furfural
Hexachlorobenzene*
Hexachlorocyclopentadiene
Hexachloroethane*
Hydrofluoric acid
Isobutyl alcohol*
Lead acetate
Lindane*
Maleic hydrazide
Mercury
Methoxychlor*
Methyl alcohol (methanol)
Methyl bromide
Methyl chloride
2,2'-Methylenebis
(3,4,6-trichlorophenol)
(hexachlorophene)
[acute waste per 261.31]
Methylene chloride*
Methyl ethyl ketone*
4-Me thyl-2-pentanone
(methyl isobutyl ketone)
Naphthalene
Nitrobenzene*
p-Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentachlorophenol*
[acute waste per 261.31]
Phenol*
Pyridine*
Resorcinol
Safrole
Selenium disulfide
Silvex [acute waste per 261.31]
1,1,2,2-Tetrachloroethane*
Tetrachloroethylene*
2,3,4,6-Tetrachlorophenol*
[acute waste per 261.31]
Thiram
Toluene*
1,1,1-Trichloroethane*
(methyl chloroform)
Trichloroethylene*
Trichlorononofluoromethane '
(Freon 11*)
2,4,5-Trichlorophenol*
[acute waste per 261.31]
2,4,6-Trichlorophenol*
[acute wasSFper 261.31]
U067
U077
U115
U122
U125
U127
U130
U131
U134
U140
U144
U129
U148
U151
U247
U154
U029
U045
U132
106-93-4
107-06-2
75-21-8
50-00-0
98-01-1
118-74-1
77-47-4
67-72-1
7664-39-3
78-83-1
301-04-2
58-89-9
123-33-1
7439-97-6
72-43-5
67-56-1
74-83-9
74-87-3
70-30-4
U080
U159
U161
U165
U169
U170
U184
U185
U242
U188
U196
U201
U203
U205
U233
U209
U210
U212
U244
U220
U226
U228
U121
U230
U231
75-09-2
78-93-3
108-10-1
91-20-3
98-95-3
100-02-7
76-01-7
82-68-8
87-86-5
108-95-2
110-86-1
108-46-3
94-59-7
7488-56-4
93-72-1
79-34-5
127-18-4
137-26-8
108-88-3
71-55-6
79-01-6
75-69-4
95-95-4
88-06-2
118
-------
PEST/DIS-8
2,4,5-Trichlorophenoxyacetic acid U232 93-76-5
(2,4,5-T)*
[acute waste per 261.31]
Warfarin «0.3%) U248 81-81-2
Xylene U239 1330-20-7
Zinc phosphide «10%) U249 1314-84-7
83 ACTIVES
119
-------
CONT/DIS-1
CONTAINER DISPOSAL INSTRUCTIONS
The label of each product must bear container disposal
Instructions appropriate to the type of container.
1. Domestic use products must bear one of the following
container disposal statements:
Container Type
Statement
Non-aerosol products
(bottles, cans, jars)
Non-aerosol products
(bags)
Aerosol products
Do not reuse container (bottle, can, Jar).
Rinse thoroughly before discarding in trash.
Do not reuse bag. Discard bag In trash.
Replc.ce cap and discard containers In
trash. Do not Incinerate or puncture.
2. All other products must bear container disposal instructions,
based on container type, listed below:
Container Type
Statement
Metal
containers
(non-aerosol)
Triple rinse Tor equivalent;. Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
authorities.
Plastic containers
Triple rinse (or equivalent;. Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay out of smoke.
Glass containers
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
Fiber drums
with liners
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reused*, dispose of in the same manner.
Paper and
plastic bags
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
6ut of smoke.
Compressed gas
cylinders
Return empty cylinder for reuse (or
similar wording)
£/ Manufacturer may replace this phrase with one indicating
whether^and how fiber drum may be reused. -
120
-------
APPENDIX III
USE INDEX APPENDIX
121
-------
EPA Index to Pesticide Chemicals
h036iOi ' TRIFLURALIN*
TYPE PESTIC^JE; Herbicide
FORMULATIONS; itf-.^
FI (44.52, 462) 7""^
G (0.0952, 0.172, 0.1742, 0.22, 0.252, 0.352, 0.372, 0.52, 0.682,
0.742, 0.922, 0.932, 1.152, 1.472, 1.752, 2.652, 42, 52, 102)
WP (3.12, 102)
EC (1.5 Ib/gal, 4 Ib/gal, 5 Ib/gal)
PrD (1.752)
GENERAL WARNINGS AND LIMITATIONS; A selective, preemergent, soil incorpo
rated herbicide for the control of certain broadleaf weeds and annual
grasses. Remove existing weeds prior to application. Trifluralin con-
trols weeds as they emerge and will not control established weeds. A one
pass incorporation must be done within 24 hours after application. A
second pass, at a right angle to the first, should be made any time prior
to planting. Application and incorporation can also be postplant or lay-
by. Trifluralin should be uniformly incorporated into the top 2 to 3 in-
ches of the final seedbed. Residual plant material should be at a level
so as to allow uniform incorporation, and the soil surface should be
smooth enough to allow efficient and uniform application. Soil moisture
should be at a level that allows large clods to be broken up during in-
corporation. Soil may be shallow cultivated after planting without re-
ducing weed control provided untreated soil is not brought to the surface.
Unless otherwise specified, use the lower dosage on coarse and medium
textured soils and the higher dosage on fine textured soils. Silty clay
loams and sandy clay loam soils are transitional soils and may be class-
ified as either medium or fine textured soils. Trifluralin is not recom-
mended for use on muck soils or on'soils containing more than 10 percent
organic matter. Dosages are expressed as pounds a.i. broadcast rate per
acre. For band applications, reduce dosage in proportion to band area
actually treated. When tank mixes are used, observe all precautions and
limitations given on the labeling of tank mix chemicals. Hay be applied
in conjunction with liquid or dry bulk fertilizers. Apply in 5 to 40
gallons of water per acre by ground or 5 to 10 gallons by air, unless
otherwise specified.
Definition of Terms;
a.i. - active ingredient
TIME REQUIRED FOR CONTROL; Not located. .
PHYTCTOnCITT TO TARGET WEEDS; Not located.
PHYTOTOXICITY TO CROPS; Not located.
MODE OF ACTION; Inhibits both root and shoot growth when absorbed by the
roots of germinating plants.
•Treflan
alpha,alpha,alpha-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine
Issued: 4-17-84 1-036101-1
122
-------
PBGACB5
PL^AEiB
PBDAEAA
PCGAFEA
PEAAGAC
PBDAIBA
PBDAEAB
PAAAAi:
PAFACBC
PFMAFBB
PAAAAB?
PAFACBI
PAFACAB
PBDAKBA
PEAAGAD
PAFACBJ
PBVAGBK
PFGAEBA
EPA Index to Pesticide Chemicals
TRIFL'JRALIN
BROADLEAF WEEDS CONTROLLED;
Carpetweed
Chick weed
Field bindweed
Florida pusley
Goosefoot
Henbit (a)
Knotweed
Kochia
Lambsquarters
Pigweed
Prostrate pigweed
Puncturevine (b)
Purslane
Redroot pigweed
Rough pigweed
Russian thistle
Smart weed
Spiny amaranth
Spotted spurge
Stinging nettle
(a) Fall application only.
(b) Western U.S. onlv.
GRASSES AND OTHER MONOCOTS
PCACKBA Annual bluegrass
PCACFSM Bahiagrass
PCASKS B Bamyardgrass
PCAAIAA Brome
PCAATBK .Cheat
PCABFAA Crabgrass
PCABCBA Crowf ootgrass
PCAATBM Downy brome
PCACEBD Fall panicum
PCACUAA Foxtail
PCACUBA . Giant foxtail
! PCASIBA , Goosegrasc
PCACUBF Green foxtail
PCACEBH Guineagrass
PCACOBA .Itchgrass
PCACWoC Johnsongrass
PCACVBG Johnsongrass (seedling)
PCASHBA Junglerlce
PCABFBF Large crabgrass
PCACCBA Rice
PCACUAC Robust foxtail
PCABZAA Ryegrass
PCAAVAA Sandbur
PCACWEB Shattercane
Issued: 4-17-84
1-036101-2
123
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
GRASSES AND OTHER MONOCOTS CONTROT.T.FT) (continued)
Si jnalgrass
Smooth crabgrass
PCA5YAA Sprahgletop
PCAJ5K3C Stinkgrass
PCACEB1 Texas panicum
PCABLE3 Woolly cupgrass
PCACUID Yellow foxtail
Issued: 4-17-84 1-036101-3
124
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name Page
TERRESTRIAL FOOD CROP
(Agricultural Crops)
Alfalfa - '
Almond 5
Apricot ' 5
Asparagus 5
Barley 6
Beans, Adzuki 7
Beans, Dried-Type 7
Beans, Lisa £
Beans, Snap 6
Broccoli 9
Brussels Sprouts 9
Cabbage 9
Cantaloupe 1C
Carrot 1C
Castor Bean 11
Cauliflower . 9
Celery . 11
Citrus Fruits 11
Collsrds 12
Corn 14
C:rr., Field. . 14
Cotros 12
Cucuaber 10
Flax ' 15
Grapefruit 15
125
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name
Grapes
Guar
Hops
Kale
Lemon
Mint (peppermint, speamict)
Mucgbean
Mustard
Mustard (seed crop)
Nectarine
Okra
Onion, Dry
Orange
Peach
Peanuts
Peas
Peas, Dry
Peas, English
Peas, Field
Pecan
Peppers
Plum •
Potato
Prune
Rape
Saf flower
Sorghum
ii
126
Page
16
17
i ~
A/
1 1
^ ^
15
17
17
16
16 •
18
19
1?
20
• ie
22
20
20
Oi
^^.
21
. 22
23
24
24
24
25
25
26
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name rage
Sorghum, Milo 2o
Sugar Beets 'v 31
Sugarcane il
Sunflower 35
Tangelo 15
Tangerine 15
Tomato • jj
Turnip 34
Walnut ;•!
Watermelon J5
Wheat 3t
TERRESTRIAL NON-FOOD CROP
(Ornamental Plants and Forest Trees)
Achillea ' 56
Adriatic Bellflover 4C
African Trailing Daisy _. <•'.
Agapanthus 4C
Ageratua 36
Algerian Ivy (ground cover) -0
Apple . . 41
Arctotls .:8
Aster 43
Austrian Pine ^i
Azalea Hybritls/Cuitlvars 45
Baldcypress 41
ill
127
-------
TABLE OF CONTENTS 10 SITE LOCATION
Site Name
Balsas Fir
Barberry 1 - . i\v- ,,_
** • r"" •••"';'*i3
Bi_g Blue Lilvturf (ground cover)
Black Locust
Black Walnut
Blackgum
Blue Ceratostigma
Blue Spruce
Borwood
Calendula
California Poppv
California Privet
Carnation
Carolina' Cherrv-Laurel
Centaurea
Cherrvberrv Cotbneaster
Chinese Chestnut
Chinese Juniper
Christmas Cheer
Chrysanthemum
Cinquefoil
Common Camellia
Common Lilac (Alba)
Common Thrift
Coreopsis
Coreopsis
Cosmos
Page
<• 2.
40
41
40
41
41
38
38
41
43
41
38
41
41
40
. 45
' 41
41
• 41
40
38
40
38
4 *"
iv
128
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name p--2e
Cotoneaster -0
Cottonvooc
Cranberry Cotoneaster -1
Creeping Wireplant -0
Crown Vetch (Ornamental) •'.
Daffodil . _6
Dahlias .;
Deutzia
Dianthus _/o
e
Dimorphotheca jS
Dogvood -6
Douglas-Fir -1
Dwarf Coyotebrush (ground cover) -0
Eastern Hemlock • ••'.
English Ivy • • -0
Erect Euonyaus -1
Euonyaus Newport 1
European White Birch -i
Firethorn -2
Flowering Dogvood 1
Forget-Me-Not 38
Four O'clock . 5
Gaillardia 38
Garden Balsac .>£
Gazania -0
Gazania sangelo 40
Germander -0
129
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name Page
Gladiolus 46
Go .den Bell , ' -2
Goldmoss Sedua 40
Harlands Borwooc 42
Hetzi Holly 42
Hiryu Azalea 42
Hollvhock ' 38
Honeylocust 42
Honeysuckle . 42
Hyperions coris 4C
Iceplant (ground cover) . 40
India Hawthorn . 42
Indlca Azalea 42
Intermediate Yew 42
Iiora 36
Japanese Andromeda 42
Japanese Barberry 42
Japanese Black Pine '•2
Japanese Dogwood 42
•Japanese Holly . 42
Japanese Larch 42
Japanese Pittosponia ' 42
Japanese Privet ^2
Japanese Yew 42
Lilac 47
Littleleaf Borvood A2
Lobelia 38
130
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name Pace
Loblolly Pine
London Plane
Lucines
Marigold
Marigold
Mascarene_grass
Mock -Orange
Morning-Glorv
Mountain-Laurel
Myoporua
Myoporum laetum
Nasturtiua
Needle£oint Ivy
Nicotiana
Northern White-Cedar
Norway Maple
Norway Spruce
Ornamental and/or Shade Trees
Ornamental Bulb Plants
Ornamental Deciduous Shrubs
Ornamental Deciduous Trees
Ornamental Evergre'ens
Ornamental Flowering Plants
Ornamental Ground Covers
Ornamental Woody Shrubs
Osteospennum (ground cover)
Periwinkle
/ *
H ^
38
36
40
40
42
38
42
4C
Li
36
4C
36
42
42
42
47
46
49
49
49
49
49
50
40
38
131.
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name | Page
Peruvian Verbena (ground cover) 40
Feiuaias 43
Phlos 36
Pi- Oak 42
Pineapple Guava 42
Point Reyes Ceanothus 40
Prunus 42
Red Maple • 42
Red Oak . 42
Red Pine 42
Redbud 42
Redcedar 42
Rhododendron Hybrids/Cultlvars 51
Rockrose . 40
Rose 51
Rose Moss 36
Rosemary (ground cover) -C-
Rudbedcia 36
Rupturewort 40
Sakaki . 42
Salvla ... 35
Sancankws Viburnum • - -2
Sasanqua Camellia • . 42
Scabiosa 38
Scarlet Oak 42
Scotch Pine 42
Sedua 40
132
-------
TABLE OF CONTENTS TO SITE LOCATION
Site Name Page
Sedan confusutr
-iv >? '
54'-'*-- ousaneuse •.. .. f^-:.^
Serbiar. Bellf lower
Shasta Daisv
Shore Juniper
Shrub-Althea
Silver Maple
Snapdragon
Snow-In-Summer
Snow-On -The-Mountain
Sprer.ger Asparagus
St. John' s-Wort (ground cover)
Stocks
Strawberry (Ornamental) (ground cover)
Sugar Maple
Sunflower
Sweet Alvssum
Sweet Pea
Sweet Viburnum
Sweet William
Sweetgum
Svcaaore
Thorny Elaeagpus
Treasure Flower
Tulipj
Tuliptree
Vanhoutte Spirea
.• r>
36
42
36
4C
36
40
4C
38
41
42
36
36
36
42
38
42
42
43
41
46
43
43
T53
-------
TABLZ OF CONILNTS TO SITE LOCATION
Site Name Pag;
Verbena 41
Veronica .•• **•-. J-'i
^••••i £. ~-* -.-'vr.
Viburnum Doublefile *2
Weigela Bristol Ruby -3
White Ash -.3
White Pine 43
White Spruce 43
Willov 43
Winged Euonymus , 43
. Woolly Yarrov «,!
Wright Viburnum 43
Yev Podocarpus ' 43
Zinnia 43
(Noncrop, Wide Area, And General Outdoor Treatments)
Airport Runvays 53
Fencerovs (Non-agricultural) 53
Firebreaks 53
Highway Rights-of-Way 53
Industrial Sites • 53
Paved Surfaces 53
Railroad Rlghts-of-Way 55
Utility Rights-of Way ' " 55
AQUATIC NON-FOOD
(Aquatic Sites)
Ditchbanks 55
134
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
TERRESTRIAL FOOD CROP
/
(Agricultural Crops)
General Warnings and Liaitations; Unless otherwise specified, fc.ll ap-
plications are limited to areas receiving more than 20 inches average
annual rainfall. In most states, applications should be sade bfr.weez
October 15 and December 31. In CA, MN, MO, ND and SD, applications can
be made between September 1 and December 31. For over-wintering, ground
may be left flat or bedded-up. If ground is bedded, beds should be
knocked down to desired height before planting, moving soce treated soil
from beds into furrows. Untreated soil should not be turned up during
spring bedding operations if soil is left over winter. When prewar.tig
seedbed, established weeds should be destroyed. Weeds that becoae es-
tablished in furrows due to uncovering of untreated soil should slsc be
destroyed prior to planting. Do not apply in the fall to soils which
are wet, are subject to long periods of flooding, or where rice was
grown the previous year. Do not apply in the fall for sugarbeets, pota-
toes, and direct seeded tomatoes.
In AZ, CO, ID, MT, NV, NM, OR, UT, WA and WY, sugarbeets, red beets or
spinach should not be planted for 12 months after a spring application
or for 14 months after a fall application. Soil should be plowed to a
depth of 12 inches prior to planting sugarbeets to prevent crop injury.
Sorghum (milo), proso millet, com or oats should not be planted for 14
months after a spring application or for 16 months after e fall applica-
tion. If land has cot been irrigated, do not plant any c: these crops
for 18 months after a spring application or 20 months after a fall ap-
plication.
In areas of KS, NE, ND, OK, SD and TX where at least 20 inches of irri-
gation and/or rainfall was used, sorghum or oats should not be planted
for 12 months after an application.
In areas receiving less than 20 Inches total water, do not plant sor-
ghum, proso millet or oats for 18 months after an application. Cool,
wet weather during the early growth stage may Increase the possibility
of injury to sorghum.
In all other areas receiving greater than 20 inches ral^'-.il per •• .-:
before planting sugar beets, moldboard plow where a spri~& application
was made the previpus season; vegetables, other than thoe- listed,
should not be planted within 5 months following an application.
Homeowner dosages are expressed as oz product per IOC square fet;.
/23001AA Alfalfa 0.05 ppm (N) (forage legumes)
0.2 ppm (N) (hay)
0.75-1 Postemergence. Broadcast. Apply to established
(52 G) alfalfa stands In areas receiving less than 20
(10% G) Inches average annual rainfall. Use the lower
(4 Ib/gal EC) dosage rate on coarse textured foils and the high-
(5 Ib/gal EC) er dosage rate on medium and fine textured soils.
Issued: 4-17-84 1-036101-4
135
-------
/ 03001AA
/05001AA
Site, Dosage
and Formulation
Clb ..l./A)
Almond
Apricot
0.5-1
UOS G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(10% G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Apricot
Asparagus
Issued: 4-17-64
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
0.05 ppm (N) (nuts, stone fruits)
Preplant. Broadcast. For use on new plantings
in areas receiving less than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils with 2 to 5 percent organic matter, and 1
Ib a.i. on soils with 5 to 10 percent organic
matter.
Directed application. For use on bearing or non-
bearing, established plantings in areas receiving
less than 20 Inches average annual rainfall.
Use limited to CA for the control of field bind-
weed. Subsurface injection. Apply in the spring
using spray blades set to incorporate to a soil
depth of A to 6 inches in 40 to 80 gallons of
water per acre. Prior to application, destroy
all weeds. If soil develops cracks, eliminate by
shallow cultivating. This will prevent field
bindweed from emerging.
Broadcast. For the control of rhizome Johnson-
grass on nbnbearing and bearing, established
plantings in areas receiving less than 20 inches
average annual rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to a depth of 4 to 6 inches. To control escaped
johnsongrass, cultivate occasionally during grow-
ing season. Apply for 2 years in a row. Do not
use this dosage rate on new plantings. Do not
interplant with other crops. If treated areas are
diverted to other crop uses, plant only those
crops registered for pieplant treatments of tri-
fluralin for the next cropping season.
See Almond cluster.
0.05 ppu
Do not apply more than 1 Ib a.i. per acre on
coarse textured soils, 1.5 Ib a.i. per acre on
medium textured soils and 2 Ib a.i. per acre on
fine textured soils within a single calendar year.
1-036101-5
1-36
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance. Use, Limitations
/28063AA
Asparagus (continued)
0.5-1
(A Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
Barlev
0.75-1
(5S G)
0.63-1
(101 G)
Issued: 4-17-64
Preemergence. Broadcast. Split application to
established asparagus. Apply in the winter or
early spring after ferns are removed, but before
spear emergence.
AND
Postharvest. Broadcast. Split application to
established asparagus. Apply after harvest in the
late spring or early summer before ferning begins.
Preemergence. Broadcast. Single application to
established asparagus. Apply in the winter or
early spring after ferns are removed, but before
spear emergence.
OR
Postharvest. Broadcast. Single application to
established asparagus. Apply after harvest ir. the
late spring or early summer before ferning begins.
0.05 ppm (grain crops, hay, fodder, forage, straw,
Use limited to ID, MN, MT, ND, OR, SD, WA and WY
for the control of foxtail in summer.fallow.
Broadcast. Apply the lower dosage between July 1
and August 31, and the higher dosage between April
15 and June 30. Use a chisel plow (first pass
only) set to incorporate to a depth of 4 to 5
Inches, tandem disc set to incorporate to a depth
of 3 to 4 inches, or a field cultivator set to
incorporate to a depth of 3 to 4 inches. Plant
seed approximately 2 Inches deep the following
spring.
For the control of'foxtail in summer fallow.
Broadcast. Apply the lower dosage in August, C."5
Ib a.i per acre in July, 0.88 Ib a.i. per acre ii
June, and the higher dosage between mid-April
through May. Use a chisel plow (first pass only/
eet to incorporate to a depth of 4 to 5 inches,
tandem disc set to Incorporate to a depth of 3 to
4 inches, or a field cultivator se to a depth of
3 to 4 inches. Plant seed approximately 2 inches
deep the following spring.
1-036101-6
137
-------
/15C01AA
/15001AA
Site, Dosage
and Formulation
(ib a.i./A)
Barley (continued)
0.5-0.75
(5i G)
(10S G)
(4 Ib/gal EC)
(5 Ib/gal EC)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance. Use, Limitations
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
Beans, Adzuki
0.5-1.25
(52 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Beans, Dried-Type
Use limited to ID, MN, Ml, ND, OR, SD, WA and WY
for the control of foxtail. Fall application.
Broadcast. Use a chisel plow (first pass only)
set to incorporate to a depth of 4 to 5 inches,
tandem disc set to incorporate to a depth of 3 tc
4 inches, or a field cultivator set to incorporate
to a depth of 3 to 4 inches. Plant seed approxi-
mately 2 inches deep the following spring.
Postplant incorporated. Broadcast. For the con-
trol of foxtail. Plant seed 2 to 3 inches deep
in a well tilled seedbed. Incorporate to a depth
of 1 to 1.5 inches using a flex-tine or diamond
harrow.
May be tank mixed with triallate for the addition-
al control of wild oat.
0.05 ppo (N) (seed and pod vegetables, forage
legumes)
Preplant. Broadcast. Use 0.75 Ib a.i. or less
in areas receiving less than 20 inches average
annual rainfall, and the entire dosage range in
areas receiving more than 20 inches average annual
rainfall. Use 0.75 to 1 Ib a.i. on soils with 2
to 5 percent organic matter, and 1 to 1.25 Ib a.i.
on soils with 5 to 10 percent organic matter.
0.05 ppo (N) (seed and pod vegetables, forage
legumes)
General Information; Dried-type beans include
kidney, navy and pinto beans.
1.07-2.13 oz prod- Preplant. Broadcast.
uct/100 sq.ft
(1.751 G)
(5% G) '
1.6-2.13 oz prod-
uct/100 sq.ft
(1.75Z G)
Preplant. Broadcast. Apply the lower dosage on
sandy soils containing 2 to 5 percent organic
matter and the higher dosage on sandy soils con-
taining 5 to 10 percent organic matter.
Issued: 4-17-84
1-036101-7
138
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and ronnuiatin
-
TRIFLURALIN
Tolerance, Use, Limitations
Beans, Dried-Type (continued)
0.75-1
(5X G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(0.22 G)
(0.252 G)
(52 G)
(5 Ib/gal EC)
0.5-0.75
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
/15002AA Beans, Lima
/15003AA Beans, Snap
1.25-1.67 oz prod-
uct/100 sq.ft
(0.932 G)
(1.472 G)
(1.752 G)
(52 G)
1.25-2.5 02 prod-
uct/100 sq.ft
(1.472 G)
(52 G)
0.5-0.75
'» (0.22 G)
(0.252 G)
(52 C)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Beans, Snap
Issued: 4-17-64
Preplant. Broadcast. Use the entire dosage range
on soils containing 2 to 5 percent organic matter;
soils containing 5 to 10 percent organic matter
require the higher dosage.
Preplant. Broadcast. Use 0.75 Ib a.i. or less
in areas receiving less than 20 inches average
annual rainfall, and the entire dosage range in
areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils with 2 to 5 percent organic matter, and 1
Ib a.i. on soils with 5 to 10 percent organic
matter.
The emulsifiable concentrates may be tank mixed
with eptam.
Broadcast. Fall application.
0.05 ppm (N) (seed and pod vegetables, forage
legumes) *
Preplant. Broadcast. Apply up to 10 weeks before
planting.
Preplant.
planting.
Broadcast. Apply up to 10 weeks before
Preplant. Broadcast,
See Beans, Lima cluster.
1-036101-8
139
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and Formulation
(Ib a.i./A)
/13005AA Broccoli
/13006AA Brussels Sprouts
/13007AA Cabbage
/13CC8AA Cauliflower
(direct seeded)
1.25-1.67 oz prod-
uct/100 sq.ft .
(1.472 G)
(52 G)
0.5-0.75
(0.22 G)
(0.252 G)
(52 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(0.22 G)
(0.252 G)
(4 Ib/gal EC)
(transplants)
1.25-2.5 oz prod-
uct/100 sq.ft
(0.932 G)
(1.472 G)
(52 G)
0.5-1
(0.22 G)
(0.252 G)
(52 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Brussels Sprouts
Cabbage
TRIFLURALIN
Tolerance, Use, Limitations
Issued: 4-17-84
0.05 ppm (N) (leafy vegetables)
.Direct seeded cole crops have exhibited marginal
tolerance to recommended rates of trifluralin.
Stunting or reduced stands may occur. Do not ap-
ply after transplanting.
Preplant.
planting.
Broadcast. Apply up to 10 weeks before
Preplant. Broadcast. For use in areas receiving
more than 20 inches average annual rainfall. Ap-
ply the lower dosage on coarse and medium textured
soils and the higher dosage on fine textured soils
and soils containing 2 to 5 percent orga-ic mat-
ter.
Preplant. Broadcast. For use in areas receiving
less than 20 inches average annual rainfall. Ap-
ply the higher dosage on soils containing 2 to 1C
percent organic matter.
Pretransplant. Broadcast.
Pretransplant. Broadcast. Use 0.75 Ib a.i. or
less In areas receiving less than 20 inches aver-
age annual rainfall, and the entire dosage ranee
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils with 2 to 5 percent organic matter, and 1
Ib a.i. on soils with 5 to 10 percent organic
matter.
See Broccoli cluster.
See Broccoli cluster.
1-036101-9
140
-------
/IOOGZAA
/10G10AA
/I4003AA
Site, Dosage
and FcnBula'io:
(Ib a.i./A)
Cantaloupe
Cucumber
1.25-2.5 02 prod-
uct/100 sq.ft
(1.475 G)
1.25-2.5 oz prod-
uct/100 sq.ft
(1.47: G)
(51 G)
.0.5-1
(55 G)
(102 G)
(4 Ib/gal EC)
'(5 Ib/gal EC)
Carrot
1.25-2.5 oz prod-
uct/100 sq.ft
(0.933; G)
(1.475 G)
(55 G)
1.25-2.5 oz prod-
0.5-1
(0.25 G)
(0.255 G)
(4 ib/gal EC;
(5 Ib/ga2 EC"-
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
0.05 ppm (N) (cucurbits)
Preplant. Broadcast.
Postemergence. Broadcast. Apply to soil vi.&n
foliage is dry and plants have 3 to 4 true leaves.
Postemergence. Directed application. Apply to
the soil between the rows and beneath plants which
are in the 3 to 4 true leaf stage. Set incorpor-
ation equipment to throw treated sell around the
plants during incorporation. Use 0.75 Ib a.i. or
less in areas receiving less than 20 inches aver-
age annual rainfall, and the entire dosage range
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils with 2 to 5 percent organic matter, and 1
Ib a.i. on soils with 5 to 10 percent organic
matter.
1.0 ppm
Preplant. Broadcast. Apply up to 10 weeks before
planting.
Issued: 4-17-64
Preplant. Broadcast. Use 0.75 Ib a.i. or less
in areas receiving less than 20 inches average
annual rainfall, and the entire cc-sage range in
areas receiving more than 20 incLet average annual
rainfall. Use 0.75 Ib a.i. or more on soils with
2 to 5 percent organic matter, arc 1 Ib a.i. on
soils with 5 to 10 percent organ::, aatter.
1-036101-10
141
-------
/27CC1AA
/13002AA
/02000AA
Site, Dosage
and Formulation
(ib a.i./A)
Castor Bean
0.5-1
(52 G)
(10S G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Cauliflower
Celerv
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
N.F.
Preplant. Broadcast. Use 0.75 Ib a.i. or less
in areas receiving less than 20 inches average
annual rainfall, and the entire dosage range in
areas receiving more than 20 inches average annu
rainfall. Use 0.75 Ib a.i. or more on soils wit
2 to 5 percent organic matter, and 1 Ib a.i. on
soils with 5 to 10 percent organic matter.
See Broccoli cluster.
0.05 ppm (N) (leafy vegetables)
(direct seeded and transplant)
0.5-1 Preplant or pretransplant. Broadcast. For use
(4 Ib/gal EC) in areas receiving less than 20 inches average
(5 Ib/gal EC) annual rainfall. Use 0.75 Ib a.i or more on soils
with 2 to 5 percent organic matter, and 1 Ib a.i. •
on soils with 5 to 10 percent organic matter.
Citrus Fruits
0.5-1
(5X G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(5* G)
(10* G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(5* G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.05 ppn (N)
General "^ formation; For continued weed control,
apply 2 times a year at 4 to 6 month intervals.
Preplant. 'Broadcast. For use on new plantings
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. on fine tex-
tured soils containing 2 to 5 percent organic
matter.
Preplant. Broadcast. For use on new plantings
In areas receiving less than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils containing 2 to 5 percent organic matter,
and 1 Ib a.i on soils with 5 to 10 percent crga-i;
matter.
Directed application.
established plantings.
For use on nonbearing,
Issued: 4-17-84
1-036101-11
142
-------
/130C9AA
/13011AA
/28007AA
Site, Dosage
and Formulation
(Ib a.i./A)
Collards
Kale
0.5-0.75
(0.22 G)
(0.252 G)
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Cotton
0.5-1.25
(0.21 G)
(0.251 G)
(51 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1-1.25
(0.352 G)
(0.52 G)
(52 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.75-1.25
(52 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-84
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
0.05 ppm (N) (leafy vegetables)
Pieplant. Broadcast.
Preplant. Broadcast. Apply the lower dosage : r
anticipated light weed pressure and the higher
dosage for anticipated heavy weed pressure.
0.05 ppo (N) (cottonseed)
Plant only rice or crops for which trifluralin can
be applied as a preplant treatment in the sea SGI.
following a double rate treatment. Plant after
early season adverse weather conditions have pa? s-
ed, especially when using higher rate programs.
Cool, wet weather early in the growth cycle causes
additional stress to the cotton plant,, which may
result in reduced stands, delayed maturity and re-
duced yields. Wheat or barley can be planted in
the fall following a postemergence application.
When applying postplant, care must be taken not
to disturb the seed.
Broadcast.' Apply before planting, at planting,
or immediately after planting. Use 0.75 Ib a.i.
or less in areas receiving less than 20 inches
average annual rainfall, and the entire dosage
range in areas receiving more than 20 inches aver-
age annual rainfall. Use 0.75 to 1 Ib a.i. on
soils with 2 to 5 percent organic matter, and 1
to 1.25 Ib a.i. on soils with 5 to 10 percent or-
ganic matter.
Use limited to AL, AR, northern FL, GA, LA, MS,
southeastern MO bootheel, NC, NM, OK, SC, IN and
IX.. 'Broadcast. Fall application.
Use limited to AZ, CA and NV.
application.
Broadcast. Fall
1-036101-12
143
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index Co Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Gorton (continued)
0.5-1.25
(51 G)
(lOX G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
^5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
0.75-1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gel EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Broadcast. Fall application. Use 0.75 Ib a.i on
coarse textured soils with 2 to 5 percent orgarl:
matter, and 1 to 1.25 Ib a.i. on coarse texture-:
soils with 5 to 10 percent organic matter.
Preplant. Broadcast. For the control of fail
panicum on coarse and medium textured soils.
Use limited to all cotton producing states ei:c::
AZ and CA. Preplant. Broadcast. Spring or fell
application for the control of rhizome Johns ..u-
grass. Prepare the soil using a chisel plow or
similar equipment to bring rhizomes to the &-.. :1
surface. Follow with a disc 2 times before ar-
plicatlon to cut the rhizomes into small 2 t<. J
inch pieces. Incorporate to a depth of 4 tc 6
inches. To remove escaped plants, cultivation
during growing season is necessary. Apply for 2
consecutive years.
Use limited to LA. Preplant. Broadcast. F:r the
control of' pigweed and seedling johnsongrass.
Use limited to the TX Gulf Coast counties of
Brazoria, Calhoun, Chambers, Fort Bend, Galvestcr.,
Harris, Jackson, Jefferson, Liberty, Matagorca,
Orange, Victoria, Waller and Wharton. Preplan:.
Broadcast. Apply up to 2 weeks before planting.
Use limited to all cotton producing states except
AZ and CA. Preplant or preemergence. Broadcast.
Do not apply on sandy, loamy sand or fine sa-dy
loam soils, or on cotton planted in furrows in
west TX. Apply the lower dosage on sandy loam
soils low In organic matter in AR, LA and MS. DC
not plant treated land with crops other than cot-
ton until 1 year after last application, or use
on sandy or coarse textured soils having less than
1 percent organic matter In MM.
lank mix with fluometuron.
Preplant. Broadcast. Follow with a preemergence
surface application of fluometuron.
1-036101-13
144
-------
/28005AA
/28006AA
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Cotton (continued)
0.5-1
(4 Ib/gai EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1.25
(52 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Com
0.38-1
(4 Ib/gal EC.)
(5 Ib/gal EC)
Com, Field
Issued: 4-17-64
Use limited to areas east of the Mississippi Rive:
plus AR, southeastern MO, LA and eastern IX. Pre-
plant. Broadcast. Follow with a preemergence
application of diuron.
Preplant. Broadcast. Apply up to 30 days before
planting.
Tank mix with norflurazon.
May be followed with a preemergence surface ap-
plication of norflurazon.
Use limited to AZ, CA, NM, and west IX.
gence. Broadcast.
Tank mix with prometryn.
Preaer-
Postemergence. Directed application. Apply
anytime up to layby, but not less than 90 days
before harvest. Direct spray between the rows a:
beneath emerged cotton plants. Use 0.75 Ib a.i.
or less in areas receiving less than 20 inches
average annual rainfall, aad the entire dosage
range in areas receiving more than 20 inches ave:
age annual rainfall. Use 0.75 to 1 Ib a.l. on
soils with' 2 to 5 percent organic matter, and 1
to 1.25 Ib a.i. on soils with 5 to 10 percent or-
ganic matter.
Postemergence. Broadcast or directed spray. Ap-
ply from the 4 true leaf stage up to layby, but
not less than 90 days before harvest.
0.05 ppm (N) (grain (exc. popcorn), forage,
fodder)
Do not apply to corn grown for seed.
Postemergence. Broadcast or directed spray.
the control of shattercane.
May be rank mixed with atrazine.
0.05 ppe (N) (grain (exc. popcorn), forage,
fodder)
Do nor apply to corn grown for seed.
For
1-036101-14
145
-------
/28009AA
/02002AA
/02004AA
/'02007AA
/02008AA
Site, Dosage
and Formulation
(Ib a,i
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Corn, Field (continued)
4 ••"
0.38-1
(4 Ib/gal EC)
(5 Ib/gai EC)
Cucumber
Flax
0.5-1
(5: G)
do: G)
(4 Ib/gal EC)
Grapefruit
Lemon
Tang elo
Tangerine
1-2
(105 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Postemergence. Directed or over-the-top spray.
Prior to application, cultivate to remove estab-
lished weeds and to cover the base of the plants
with soil. Apply only after the crop is well
established (8 inches or taller). Use the lower
dosage rate when light weed pressure is antici-
pated, and the higher dosage when heavy weed
pressure is anticipated.
See Cantaloupe cluster.
0.05 ppm (seed, straw)
Do not plant until the seedbed has warmed up.
Preplant. Broadcast. Apply in the fall after
September 1 and before December 31. Spring incor-
poration should be shallow to maintain a fire
seedbed. Plant seed at least 1.5 inches deep with
a press or hoe drill, to a moist well packed seed-
bed.
0.05 ppm (N) (citrus fruits)
General Information: For continued weed control,
apply 2 times a year at 4 to 6 month intervals.
Directed application. For use on bearing or
nonbearing established plantings.
Directed spray. For the control of rhizome
johnsongrass on nonbearing and bearing, estab-
lished plantings In areas receiving less that: 20
Inches average annual rainfall. Thoroughly work
the soil to bring rhizomes nearer the surface.
incorporate to a depth of 4 to 6 inches. To con-
trol escaped johnsongrass, cultivate occasionally
during growing season. Apply for 2 years in a
row. Do not use this dosage rate on new plant-
Ings. Do not interplant with other crops. If
treated areas are diverted to other crop uses,
plant only those crops registered for preplant
treatments of trifluralin for the rsxt cropping
season.
Issued: 4-17-84
1-036101-15
146
-------
/01014AA
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use. Limitations
Grapefruit cluster (continued)
(4 Ib/gal EC)
(5 Ib/gal EC)
Grapes
0.5-1
(52 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-2
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.75-1
(51 G)
1-2
(51 G)
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-84
Use limited to CA for the control of field bice-
weed. Subsurface injection. Apply in the spring
using spray blades set to incorporate to a soil
depth of 4 to 6 inches in 40 to 80 gallons of
water per acre. Prior to application, destroy
all weeds. If soil develops cracks, eliminate by
shallow cultivating. This will prevent field
bindweed from emerging.
0.05 ppm (N)
Sixty day preharvest interval in areas receiving
less than 20 inches average annual rainfall.
Do not apply more than 1 Ib a.i. per acre on neat
treated grape rootings.
Preplant. Broadcast. For use on new plantings
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. on fine tex-
tured soils containing 2 to 5 percent organic
matter, and 1 Ib a.i. on soils containing 5 to 10
percent organic matter.
Preplant. Broadcast. For use on new plantings
in areas receiving less than 20 inches average
annual rainfall. Use 1.5 Ib a.i. or less on
coarse and medium textured soils, and 1.5 Ib a.i.
or more on fine textured soils or soils containing
2 to 10 percent organic matter.
Preplant. Broadcast. For use on soils containing
2 to 5 percent organic matter to be planted to new
plantings.
Directed application. For use on bearing or non-
bearing, established plantings in areas receiving
less than 20 Inches average annual rainfall.
Broadcast. For the control of rhizome Johnson-
grass on nonbearlng and bearing, established
plantings in areas receiving less than 20 inches
average annual rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to a depth of 4 to 6 inches. To control escaped
Johnsongrass, cultivate occasionally during grow-
ing season. Apply for 2 years in a row. Do not
1-036101-16 - -
147
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALLN
Tolerance, Use, Limitations
Grapes (continued)
/26011AA
/15G12AA
/08020AA
/28012AA
4 '
I
(4 Ib/gal EC)
(5 Ib/gal EC)
Guar
Hungbean
0.5-0.75
(0.2Z G)
(0.25Z G)
0.38-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
Kale
Lemon
Mint (peppermint
spearmint)
0.5-0.75
(4 Ib/gal EC.)
(5 Ib/gal EC)
Mungbean
Issued: 4-17-84
use this dosage rate on new plantings. Do not in-
terplant with other crops. If treated area- are
diverted to other crop uses, plant only those
crops registered for prepiant treatments of tri-
fluralin for the next cropping season.
Use limited to CA for the control of field blad-
weed. Subsurface Injection. Apply in the spring
using spray blades set to incorporate to a EC11
depth of 4 to 6 inches in 40 to 80 gallons of
water per acre. Prior to application, destroy all
weeds. If soil develops cracks, eliminate by
shallow cultivating. This will prevent field
bindweed from emerging.
0.05 ppm (N) (forage legumes)
0.05 ppo (N) (seed and pod vegetables)
2.0 ppm (mungbean sprouts)
Prepiant. Broadcast.
Prepiant. 'Broadcast. Apply the lower dosage for
anticipated light weed pressure and the higher
dosage for anticipated heavy weed pressure.
0.05
(N)
Dormant application. Broadcast. Apply the hlghe:
dosage on fine textured soils and soils with 2 to
10 percent organic matter.
See Collards cluster.
See Grapefruit cluster.
0.05 ppm
2.0 p.i
(N)
(hay)
(oil)
For use on established mint. Broadcast. Use in-
corporation equlpa«nt that will insure thorough
soil mixing with minimum damage to the crop.
See Guar cluster.
1-036101-17
148
-------
• i v~ ~•
* J v. «...
/13C21AA
/05003AA
/05004AA
Site, Dosage
and Formulation
Ub a.i./A)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Mustard (seed crop) 0.05 ppo (N) (leafy vegetables)
0.5-0.75
(5Z G)
do: G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Mustard
0.5-0.75
(0.2* G)
(0.25X G)
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(5S G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Nectarine
Peach
0.5-1
(IDS G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Use limited to MN, MI and ND on mustard grown for
seed. Freplant. Broadcast. Apply the lower
dosage on coarse textured soils and the higher
dosage en medium and fine textured soils.
0.05 ppm (N) (leafy vegetables)
Preplant. Broadcast.
Preplant. Broadcast. Apply the lower dosage for
anticipated light weed pressure and the higher
dosage for anticipated heavy weed pressure.
Use limited to MN, MI and ND on mustard greens
grown for processing. Preplant. Broadcast. Ap-
ply the lower dosage on coarse textured soils and
the higher dosage on medium and fine textured
soils.
0.05 ppm (N) (stone fruits)
Preplant. Broadcast. For use on new plantings
in areas receiving less than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
fine textured soils containing 2 to 5 percent
organic matter, and 1 Ib a.i. on soils containing
5 to 10 percent organic matter.
Directed application. For use on bearing or nor-
beariig e£-_a:lished plantings in areas receiving
less than 20 inches average annual rainfall.
Broadens:. ?rr the control of rhizome Johnson-
grass on nonbeariag or bearing, established
plant ins? ii. areas receiving less than 20 inches
average a.-r.'_=.l rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to d c'ept:: of 4 to 6 inches. To control escaped
johnsongr££s, cultivate occasionally during grow-
ing season. Apply for 2 years in e. row. Do not
use this dosage rate on new plantings. Do not in-
terplant with other crops. If treated areas are
1-036101-18 -. -
149
-------
•„ /15015AA
/14011AA
Site, Dosage
and Foraulation
(Ib a.i./A)
Nectarine cluster (continued)
EPA Index to Pesticide Chemicals
TRIFLURAUN
Tolerance, Use, Limitations
(4 Ib/gal EC)
(5 Ib/gal EC)
Okra
1.25-2.5 oz prod-
uct/100 sq.ft
(0.931 G)
(1.47X G)
(1.75J G)
(SVG)
1.67-2.5 oz prod-
uct/100 sq.ft
(1.751 G)
0.5-1
(0.2S G)
(0.25X G)
(51 G)
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Qpioc, Dry
0.38-0.63
(4 Ib/gal EC)
(5 Ib/gal BC)
diverted to other crop uses, plant OL-> mose
crops registered for preplant trfc.it:-.:.-.:. zf tr:-
fluralin for the next cropping season.
Use limited to CA for the contr:1 c: rlild birl-
weed. Subsurface injection. App^y in tne spnag
using spray blades set to incorprra;t :: a sol-
depth of 4 to 6 inches In 40 to 80 g?.llcrs of
water per acre. Prior to application, destroy all
weeds. If soil develops cracks, ellrl^cre by
shallow cultivating. This will prevent field
bindweed from emerging.
0.05 ppm (N) (seed and pod vegetables,)
Preplant. Broadcast. Apply up tr. '.'. vf*--.s btf:.re
planting.
Preplant. Broadcast. Apply the lc-v-..r dosage oc
sandy soils containing 2 to 5 percent orga-ic
matter and the higher dosage on easi;. sells ccr.-
taining 5 to 10 percent organic mart?-.
Preplant. Broadcast. Use 0.75 IV £ '.. cr less
in areas receiving less than 20 ice;.-.» overage
annual rainfall, and the entire dc&i,e rs:ige in
areas receiving more than 20 Inches average annual
rainfall. Use 0.75 Ib a.l. or mere cr sells con-
taining 2 to 5 percent organic matter, and 1 Ib
a.i. on soils containing 5 to 10 per:t-t srgaric
matter.
0.05 ppn (N) (root vegetables)
Avoid spraying the onion tops o: er, ;. ...'.: .
Postemergence. Directed spray berwefr the rev .
Issued: 4-17-64
1-036101-19
150
-------
728016 AA
/28074AA
Site, Dosage
and Formulation
(1M>. i./A).
•*.\i
Orange
1-2
(5°. G)
do: G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.38-0.5
(4 Ib/gal EC)
(5 Ib/gal EC)
Peas, Pry
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-84
EPA Index co Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
, ^ •«
••. fOUV ->
V;£*
0.05 ppm (N) (citrus fruits)
Directed application. For use on bearing o:
rionbearing, established plantings.
Broadcast. For the control of rhizome Johnson-
grass on nonbearing and bearing, established
plantings in areas receiving less than 20 inches
average annual rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to a depth of 4 to 6 inches. To control escapee
johnsongrass, cultivate occasionally during grow-
ing season. Apply for 2 years in a row. Do nor
use this dosage rate on new plantings. Do not ic-
terplant with other crops. If treated areas are
diverted to other crop uses, plant only those
crops registered for preplant treatments of tri-
fluralin for the next cropping season.
Use limited to CA for the control of field bind-
weed. Subsurface Injection. Apply in the spring
using spray blades set to incorporate to a soil
depth of 4 to 6 Inches in 40 to 80 gallons of
water per acre. Prior to application, destroy all
weeds. If soil develops cracks, eliminate by
shallow cultivating to prevent field bindweed fros
emerging.
See Nectarine cluster.
0.05 pptE (N) (seed and pod vegetables, forage
legumes;
Use limitec to ID, OF. and WA for the control of
wild oats. Preplant. Broadcast. Apply from 3
weeks u to immediately before planting.
Tank mix with diallate; or trlallate.
0.05 pptt (N: (seed and pod vegetables, forage
legumes)
Preplant. Broadcast.
1-036101-20
151
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage
and Formulation
(Ib a.i./A)
Peas, Dry (continued)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
/15009AA Peas. English
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
0.38-0.5
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
/15008AA Peas. Field
Tolerance, Use, Limitations
1.25-2.5 oz prod-
uct/100 sq.ft
(0.93Z G)
(1.47Z G)
(1.75Z G)
(5Z G)
1.67-2.5 oz prod-
uct/100 sq.ft
(1.75Z G)
0.5-1
(0.2Z G)
(0.251 G)
(51 G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Use limited to ID, OR and WA.
Broadcast.
Fall application.
0.05 ppffi (N) (seed and pod vegetables, forage
legumes)
Preplant. Broadcast.
Use limited to ID, OR and WA. Preplant. Br.:
cast. Apply up to 3 weeks before planting.
Tank mix with triallate.
Use limited to ID, OR and UA. Broadcast. Fa:
application.
0.05 ppm (N) (seed and pod vegetables, forage
legumes)
General Information: Field peas includes covpeas
and blackeyed peas.
Preplant. Broadcast. Apply up to 10 weeks before
planting.
Preplant. Broadcast. Apply the lower dosage on
sandy soils containing 2 to 5 percent organic
matter and the higher dosage on sandy soils con-
taining 5 to 10 percent organic matter.
Pr'eplan t or preemergence. Broadcast.
fore or Immediately after planting. Use G..J ID
a.i. or less in areas receiving less than 2~ ::. -
ches average annual rainfall, and the entire doe-
age range In areas receiving more than 20 inches
average annual rainfall. Use 0.75 Ib a.i. or tcor»
on soils containing 2 to 5 percent organic =~.:--t:
and 1 Ib a.i. on soils containing r to 10 percent
organic matter.
1-036101-21
152
-------
/2601JAA
/03008AA
Site, Dosage
and Formulation
lib a.i./A)
Peanuts
0.5-0.75
(10% WF)
(Spanish)
0.5
(0.2S G)
(0.25Z G)
•(51 G)
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5
(4 Ib/gal EC)
(5 Ib/gal EC)
EPA Index to Pesticide Cheoicals
TRIFLURALIN
Tolerance. Use, Limitations
0.05 ppm (N) (peanuts, forage legumes)
0.1 ppm (hulls)
Preemergence. Broadcast.
Formulated with diphenamid.
Use limited to OK and TX. Preplant or preemer-
gence. Broadcast. Apply to coarse textured soils
before planting, at planting or immediately after
planting. Do not disturb the seed when incorpo-
rating after planting.
Use limited to OR and IX. Preplant. Broadcast.
Apply up to 10 days prior to planting to coarse
textured soils.
Tank mix with vernolate.
(10S G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
(Florunner, Florigiant)
0.5-0.75 Preplant. Broadcast. For use on coarse and medi-
(4 Ib/gal EC) urn textured soils.
0.05 ppo (N) (nuts)
Preplant. Broadcast. For use on new plantings
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. on fine tex-
tured soils containing 2 to 5 percent organic
matter.
Preplant. Broadcast. For use on new plantings
in areas receiving less than 20 inches average
annual rainfall. Use the 0.75 Ib a.i. or more
on fine textured soils containing 2 to 5 percent
organic matter.
Preplant. Broadcast, for use on soils containing
5 to 10 percent organic matter on new plantings.
Directed application. For use on nonbearlng, or
bearing, established plantings in areas receiving
more than 20 inches average annual rainfall.
1-036101-22
153
(4 Ib/gal EC)
(5 Ib/gal EC)
i-:
(10X G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
-------
Site, Dosage
and Formulation
Uv ^..i./A)
Pecan (continued)
(4 Ib/gal EC)
(5 Ib/gal EC)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
(4 Ib/gal EC)
(5 Ib/gal EC)
/28017AA Peppers
1.25-2.5 oz prod-
uct/100 sq.ft
(0.931 G)
(1.47Z G)
(5Z G)
1.67-2.5 oz prod-
uct/100 sq.ft
U.75Z G)
0.5-1
(0.2Z G)
(0.25Z G)
(5Z G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Broadcast. For the control of rhizome johnsoc-
grass on nonbearing and bearing, established
plantings in areas receiving less than 20 inches
average annual rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to a depth of 4 to 6 inches. To control escaped
johnsongrass, cultivate occasionally during grow-
ing season. Apply for 2 years in a row. Do not
use this dosage rate on new plantings. Do not in-
terplant with other crops. If treated areas are
diverted to other cro.p uses, plant only those
crops registered for preplant treatments of tri-
fluralin for the next cropping season.
Use limited to CA for the control of field bind-
weed. Subsurface Injection. Apply in the spring
using spray blades set to Incorporate to a sell
depth of.4 to 6 Inches in 40 to 80 gallons of
water per acre. Prior to application, destroy all
weeds. If soil develops cracks, eliminate by
shallow cultivating. This will prevent field
bindweed from emerging.
0.05 ppm (N) (fruiting vegetables)
Do not apply after transplanting.
Pretransplant. Broadcast.
Pretransplant. Broadcast. Apply the lower dosage
on sandy soils containing 2 to 5 percent organic
matter and the higher dosage on sandy soilE con-
taining 5 to 10 percent organic matter.
Pretransplant. Broadcast. Use 0.75 Ib a.l. or
less In areas receiving less than 20 inches aver-
age annual rainfall, and the entire dosage range
in areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or acre on
soils containing 2 to 5 percent organic matter,
and 1 Ib a.i. on soils containing 5 to 10 percent
organic matter.
1-036101-23
T54
-------
Site, Dosage
and Formulation
(Ib a.i./A)
/05005AA
/05006AA
/14C13AA
1-2
do: G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Potato
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.38
(4 Ib/gal EC)
(5 Ib/gal EC)
0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
EPA Index to Pesticide Chemicals
TRIFLURAUN
Tolerance, Use, Limitations
*>'•'" !- '
0.05 ppm (N) (stone fruits)
Directed application. For use on bearing or non-
bearing, established plantings in areas receiving
less than 20 inches average annual rainfall.
0.05 ppm (N) (root vegetables)
General Information: Do not use in ME.
Uniformly
cover the bed and furrow with a treated layer of
soil. If the treated layer is not uniform and the
trifluralin is concentrated over the bed, potato
emergence may be retarded and stem brittleness may
occur. Do not completely cover the foliage with
treated soil after potato plants have fully emerg-
ed. Do not completely cover the foliage at subse-
quent cultivations. Do not damage potato seed
pieces or elongated sprouts with incorporation
machinery.
Broadcast. Apply after planting, before emergence
or immediately following drag-off, or after potato
plants have fully emerged. Use 0.75 Ib a.i. or
less in areas receiving less than 20 inches aver-
age annual' rainfall, and the entire dosage range
in areas receiving more than 20 inches average
annual rainfall.
Use limited to ID, OR and WA. Preplant or post-
emergence. Broadcast. For postemergence appli-
cations apply when potato plants have fully ma-
tured. Do not apply to soils containing 2 percent
or more organic matter.
For use on coarse and medium textured soils con-
taining 2 to 5 percent organic matter. Broadcast.
Apply after planting, before emergence, or Immedi-
ately following drag-off, or after potato plants
have fully emerged.
Use limited to all states except ME. For use on
soils containing 5 to 10 percent organic matter.
Broadcast. Apply after planting, before emer-
gence, or Immediately following drag-off, or
after potato plants have fully emerged.
1-036101-24
T55
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and Formulation
(Ib a.i./A)
Potato (continued)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
TRIFLURAUN
Tolerance, Use, Limitations
0.38
(4 Ib/gal EC)
(5 Ib/gal EC)
(Irish)
1.25-2.5 02 prod-
uct/100 sq.ft
(1.471 G)
Prune
/2805IAA Rape
0.5-1
(5Z G)
(10* G)
(4 Ib/gal EC)
(5 Ib/gal EC)
/28076AA Safflower
0.5-1.25
(51 G)
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-84
Use limited to KS, MN, NE, KD, OK, SD and TX.
Broadcast. Apply after planting, but prior to
crop emergence. Use 0.75 Ib a.i. or less in areas
receiving less than 20 inches avenge annual
rainfall, and the entire dosage range in areas
receiving more than 20 Inches average annual
rainfall. Use 0.75 Ib a.i. on coarse and medium
textured soils containing 2 to 5 percent organic
matter, and 1 Ib a.i. on coarse anc medium tex-
tured soils containing 5 to 10 percent organic
matter. In areas where potatoes are normally
dragged-off, apply and incorporate up to or im-
mediately after drag-off.
Tank mix with eptam.
Use limited to ID, OR and WA. Prerlant. Broad-
cast.
Tank mix with eptam.
Posttransplant. Broadcast.
See Plum cluster.
0.05 ppm (seed, straw)
Use limited to all states except A}.. Preplant.
Broadcast. Apply in the fall, or in the spring
prior to seeding.
0.05 ppo (N) (seed)
Preplant. Broadcast. Apply in the spring before
planting, or in the fall. Use 0.73 Ib a.i. or
less in areas receiving less than 20 inches aver-
age annual rainfall, and the entire dosage range
in areas receiving aore thac 20 Inches average
annual rainfall. Use 0.75 to 1 Ib a.i. on soils
with 2 to 5 percent organic matter, and 1 to 1.25
Ib a.i. on soils with 5 to 10 percent organic
matter.
1-036101-25
T56
-------
/28019AA
/24006AA
/28023AA
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Safflower (continued)
1-1.5
(5S G)
(4 Ib/gal EC)
0.75-1.25
(5S G)
(10S G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(5Z G)
Sorghuc
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Sorghum, Mllo
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Sovbeaas
Issued: 4-17-64
Preplant. Broadcast. For use in areas receiving
less than 20 inches average annual rainfall and
having soils with 10 to 20 percent organic matter.
Use limited to AZ, CA, ID, HI, NV, OR, UT, WA and
VY. Fall application. Broadcast.
Use limited to ID, Ml, NV, ND, OR, SD, UT, WA and
WY. Broadcast. Fall application. Use 0.75 Ib
a.i. or more on coarse textured soils with 2 to 5
percent organic matter, and 1 Ib a.i. on soils
containing 5 to 10 percent organic matter.
0.05 ppm (grain crops, forage, fodder)
Postemergence. Broadcast or directed spray. For
the control of shattercane.
May be tank mixed with atrazine.
0.05 ppm (grain crops, forage, fodder)
Postemergence. Directed or over-the-top spray.
Prior to application, cultivate to remove estab-
lished weeds and to cover the base of the plants
with soil. Apply only after the crop is well es-
tablished (8 inches or taller). Use the lower
dosage rate when light weed pressure is anticipat-
ed, and the higher dosage when heavy weed pressure
Is anticipated.
0.05 PTS !>'' 'se«:: and pod vegetables, forage
"General lui^ra^tir.a: Plant only rice or crops for
which trifluralin can be applied as a preplant
treats .at is the eeason following a double rate
treatment. Fiazt after early season adverse
weather conditions have passed, especially when
using higher rate programs. Cool, wet weather
early ic the growth cycle causes additional stress
to the soybean plant, which may result in reduced
stands, delayed maturity and reduced yields. Rice
control Is a 2 year program. Use the rates listed
for the first year and plant soybeans. For the
second veer, use the normal rates listed for soil
I-C36101-26
157
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage
and Formulation
(Ib a.i./A;
Sovbeans (continued)
Tolerance, Use. Limitations
0.5-1.25
(51 G)
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(0.22 G)
(0.25S G)
1-1.25
(0.35Z G)
(0.5Z G)
(51 G)
(10X G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1.25
(5Z G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(51 G)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
types and charcoal level and plant only those
crops for which trifluralin can be applied as a.
preplant treatment. Do not plant rice the second
year. Rice may be planted the third year.
Preplant or preemergence. Broadcast. Use 0.75
to 1 Ib a.i. on soils containing 2 to 5 perce-t
'organic matter, and 1 to 1.25 Ib a.i. on soils
containing 5 to 10 percent organic matter.
Preplant. Broadcast. For the control of fall
panicum on coarse and medium textured soils.
Preplant. Broadcast.
Use limited to AL, AR, northern FL, GA, LA, Y:
southeastern MO bootheel, NC, OK, SC, IN and 7X.
Broadcast. Fall application.
Broadcast. Fall application. Use 0.75 Ib a.'.
on coarse textured soils with 2 to 5 percent cr-
ganic matter, and 1 to 1.25 Ib a.i. on soils v-ith
5 to 10 percent organic matter.
Uae limited to ID, MN, MI, ND, OR, SD, WA and WY.
Preplant. Broadcast. Apply in the spring bef?re
planting, or in the fall after September 1.
Use limited to AL, AR, FL, GA, KS, LA, MS, sourh-
essrera MC, NC, OK, SC, TN and souther: YA. •-e-
plant. Broadcast. For the control of pigveec and
seedling JohaBongrass. In LA, use an aciitic:~i
0.5 Ib a.i per acre for control.
Issued: 4-17-34
1-036101-27
158
-------
EPA Index to Pesticide Chemicals
Site, Dosage
and Formulation
(Ib a.i./A)
Soybeans (continued)
0.75-1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1.5
(4 Ib/gal EC)
'(5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
TRIFLURAUN
Tolerance, Use, Limitations
0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Use limited to the IX Gulf Coast counties of
Brazoria, Calhoun, Chambers, Fort Bend, Galveston,
Harris, Jackson, Jefferson, Liberty, Matagorda,
Orange, Victoria, Waller and Wharton. Preplast.
Broadcast. Apply up to 2 weeks before planting.
Use limited to charcoal soils of AR, LA and MS.
Preplant. Broadcast.
Use limited to AR, LA, MS and IX. Preplant.
Broadcast. Apply in the spring for partial
control or suppression of rice.
AND
Use limited to AR, LA, MS and TX. Preplant.
Broadcast. Apply in the spring of the second
year for partial control or suppression of rice.
Use limited to AR, LA, MS and TX on coarse tex-
tured soils with 2 to 5 percent organic matter.
Preplant. Broadcast. Apply in the spring for
partial control or suppression of rice.
AND
Use limited to AR, LA, MS and IX on coarse tex-
tured soils with 2 to 5 percent organic matter.
Preplant. Broadcast. Apply In the spring of the
second year for partial control or suppression of
rice.
Use limited to AF., LA, MS aad IX on soils with 5
to 10 percent organic matter. Preplant. Broad-
cast. Apply in the spring for partial control or
suppression of rice.
1-1.25
(4 Ib/gal EC)
(5 Ib/gal EC)
Use limited to AR, LA, MS and TX on soils with 5
to 10 percent organic matter. Preplant. Broad-
cast. Apply in the spring of the second yetr for
partial control or suppression of rice.
OR
Issued: 4-17-64
1-036101-28
159
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Soybeans (continued)
0.75-1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
1.5
(4 Ib/gal EC)
(5 Ib/gal EC)
Use limited to AR, LA and MS on soils with 5 to
10 percent organic matter and having charcoal ;-.re-
sent. Preplant. Broadcast. Split application.
Apply in the spring of the second year for partial
control or suppression of rice.
Use limited to the eastern United States and TX.
Pieplant. Broadcast. Spring or fall application
for the control of rhizome johnsongrass. Apply
the higher dosage on fine textured soils or on
soils with 5 to 10 percent organic matter. Pre-
pare the soil using a chisel plow or similar
equipment to bring rhizomes to the soil surface.
Follow with a disc 2 times before application to
cut the rhizomes Into small 2 to 3 inch pieces.
Incorporate to a depth of 4 to 6 inches. To re-
move escaped plants, cultivation during growing
season is necessary. Apply for 2 consecutive
years.
OR
Use limited to the eastern United States and IX.
Preplant. Broadcast. Split application for the
control of rhizome johnsongrass. Apply the hi^.-.e:
dosage on fine textured soils or on soils with 5
to 10 percent organic matter. Prepare the soil
using a chisel plow or similar equipment to bring
rhizomes to the soil surface. Follow with a c.sc
2 times before application to cut the rhizomes in-
to small 2 to 3 inch pieces. Incorporate to a
depth of 4 to 6 inches. To remove escaped pla-.ts,
cultivation during growing season is necessar- .
Applv both in the spring and the fall for 2 con-
secutive years.
Use' limited to the eastern United States and " -
Preplan-. Broadcast. Spring or fall applies:_cn
for the control of rhizome johnsongrass on coarse
textured soils with 2 to 5 percent organic aa:.er.
Prepare the soil using a chisel plow or similer
equipment to bring rhizomes to the soil surface.
Issued: 4-17-64
1-036101-29
160
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage
and Formulation
(Ib a.i./A)
Soybeans (continued)
Tolerance, Use, Limitations
0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1.25
(4 Ib/gal EC)
(5 Ib/gal EC,)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Follow with a disc 2 times before application to
cut the rhizomes into small 2 to 3 inch pieces.
Incorporate to a depth of 4 to 6 inches. To re-
move escaped plants, cultivation during growing
season is necessary. Apply for 2 consecutive
years.
OR
Use limited to the eastern United States and IX.
Preplant. Broadcast. Split application for the
control of rhizome johnsongrass on coarse textured
soils with 2 to 5 percent organic matter. Prepare
the soil using a chisel plow or similar equipment
to bring rhizomes to the soil surface. Follow
with a disc 2 times before application to cut the
rhizomes into small 2 to 3 inch pieces. Incorpo-
rate to a depth of 4 to 6 inches. To remove es-
caped plants, cultivation during growing season
is necessary. Apply both in the spring and fall
for 2 consecutive years.
Preplant. Broadcast. For the control of rhizome
johnsongrass. Prepare the soil using a chisel
plow or similar equipment to bring rhizomes to the
soil surface. Follow with a disc 2 times before .
application to cut the rhizomes into small 2 to 3
inch pieces. Incorporate to a depth of 4 to 6
inches. To remove escaped plants, cultivation
during growing season is necessary. Apply up to
2 weeks before planting for 2 consecutive years.
Tank mix with metribuzin.
Preplant. Broadcast. For the control of shatter-
cane . Incorporate to a depth of 4 to 6 inches
using 2 passes in opposite directions. For con-
tinued control, cultivate during the growing _
season.
Preplant. Broadcast. Apply up to 14 days days
prior to planting.
Tank mix with chloramben, ammonium salt; veraol-
ate; alachlor; metribuzin; metolachlor; or chlor-
amben, ammonium salt and metribuzi: .
OR
Issued 5 4-17-84
1-036101-30
161
-------
EPA Index co Pesticide Chemicals
TRIFLURALIN
/28020AA
/2500SAA
Site, Dosage
and Formulation
(Ib a.i./A)
Soybeans (continued)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.28-0.56
(1.5 Ib/gal EC)
Sugar Beets
Tolerance, Use, Limitations
0.5-0.75
(51 G)
(10* G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
sugarcane
(plant cane)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-S4
Preplant. Broadcast. Follow with an overlay ap-
plication of chloramben; alachlor; metribuzin; or
metolachlor.
Preplant. Broadcast. Incorporate within 3 days
after application.
May be tank mixed with chloramben; or metribuzin.
Formulated with oryzalln.
0.05 ppo (N) (root vegetables)
General Information; Cover exposed beet roots
with soil before applying to reduce the possibi-
lity of girdling. Do not damage sugar beet tap-
root with machinery.
Postemergence. Broadcast. Apply as an over-the-
top spray when plants are 2 to 6 inches tall. Use
the higher dosage rate on medium and fine textured
soils receiving more than 20 inches average annual
rainfall. Set incorporation machinery to throw
treated soil towards the plants in the row.
Use limited to CA, CO, -ID, KS, MI,. NE, OR, TX, UT,
WA and VY.' Postemergence. Broadcast. Incorpo-
rate with a tine-tooth harrow set to cut 1 or 2
inches deep, 2 times over the field in opposite
directions.
Postemergence. Broadcast. Use 0.63 Ib a.l. or
less in areas receiving less than 20 Inches aver-
age annual rainfall, and the entire dosage range
in areas receiving more than 20 inches average
annual rainfall. Apply anytime after the first
true leaves have formed until the beets are 6 in-
ches tall.
lank mix with eptam.
0.05 ppm (N)
Postplant. Broadcast. Apply in the fall on firm-
ly packed beds Immediately after seed pieces are
planted. Do not damage seed pieces with incorpo-
ration equipment.
AND
1-036101-31
162
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitat1ons
Sugarcane (continued)
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
3-4
(4 Ib/gal EC)
(5 Ib/gal EC)
(ratoon cane)
3-4
(4 Ib/gal EC)
(5 Ib/gal EC)
(plant cane and
1-2
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Preemergence or post emergence. Broadcast. Apply
in the spring before or shortly after the cane
emerges. Loosen rain packed beds 2 to 3 inches
deep before application. Do not damage seed
pieces or emerging shoots with incorporation
equipment.
Use limited to HI for the control of most annual
grasses, Including guineagrass. Postplant.
Broadcast. Apply to the soil surface before weeds
and cane emerge. Form or roll beds before appli-
cation. Rainfall or sprinkler irrigation is ne-
cessary immediately after application.
Use limited to HI for the control of most annual
grasses, including guineagrass. Postharvest.
Broadcast. Apply to the soil surface before weeds
emerge. Remove crop residue before application.
Rainfall or sprinkler irrigation is necessary im-
mediately after application.
ratoon cane).
Use limited to LA and IX. Preemergence or post-
emergence. Broadcast. Apply in the spring from
before or shortly after the cane emerges up to
layby, and after the beds have been shaved or
false shaved. Before application, loosen rain
packed beds 2 to 3 inches deep. Do not damage
seed pieces or emerged shoots with incorporation
equipment. For layby applications, a rolling cul-
tivator or bed chopper may be used for incorpora-
tion. Incorporate to a depth of 3 to 4 inches
when using bed chopper and 2 to 4 inches deep when
using rolling cultivator.
Use limited to LA for the control of itchgrass.
Postemp-gence. Broadcast. Apply at layby. Use
a rolling cultivator or bed chopper for incorpo-
ration. Incorporate tc a depth of 4 inches when
using bed chopper and 2 to 4 inches deep when
using rolling cultivator.
Issued: 4-17-84
1-036101-32
163
-------
EPA Index to Pesticide Chemicals
/28021AA
/11005AA
Site, Dosage
and Formulation
(Ib a.i./A)
Sunflower
1.25-2.5 oz prod-
uct/100 sq.ft
(5S
G)
0.5-1
(5Z G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Tangelo
Tangerine
Tomato
(direct seeded)
1.25-2.5 oz prod-
uct/100 sq.ft
(0.93Z G)
(1.47Z G)
(51 G)
Issued: 4-17-84
TRIFLURAJJN
Tolerance, Use, Limitations
* Si
0.05 ppm (N) (seed)
Preplant. Broadcast.
Preplant. Broadcast. Use 0.75 Ib a.i. or less
in areas receiving less than 20 inches average
annual rainfall, and the entire dosage range in
areas receiving more than 20 inches average ar.nua:
rainfall. Use 0.75 Ib a.l. or more on soils con-
taining 2 to 5 percent organic matter, and 1 Ib
a.i. on soils containing 5 to 10 percent organic
matter. Apply in the spring or the fall.
Preplant. Broadcast. .
Tank mix with chloramben.
' OR
Preplant. Broadcast. May be followed by a broad-
cast or band overlay application of thloranben at
planting.
Use limited to MN, ND and SD. Preplant. Broad-
cast. Use 0.75 Ib a.i. or less In areas receiving
less than 20 Inches average annual rainfall, and
the entire dosage range In areas receiving more
than 20 inches average annual rainfall. Apply IE
the spring prior to planting or in the late fall
before the ground freezes.
Tank mix with eptam.
See Grapefruit cluster.
See Grapefruit cluster.
0.05 ppo (N) (fruiting vegetables)
General Information; Do not apply after trai.-.-
planting.
Prejlant.
planting.
Broadcast. Apply up to 10 weeks before
1-036101-33
164
-------
EPA index to Pesticide Chemicals
/13026AA
Site, Dosage
and Formulation
(Ib a.i./A)
Tomato (continued)
0.25
(3.IX WP)
0.5-1
(51 G)
(10X G)
(4 Ib/gal EC)
(5 Ib/gal EC)
TRIFLURALIN
Tolerance, Use, Limitations
(transplant)
1.25-2.5 oz prod-
uct/100 sq.ft
(0.93X G)
U.47Z G)
(1.75Z G)
(51 G)
1.67-2.5 oz prod-
uct/100 sq.ft
(1.75S G)
0.5-1
(0.2* G)
(0.25Z G)
(51 G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Turnip
0.5-0.75
(0.21 G)
.(0.25Z G)
0.38-1
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Use limited to CA. For use on tomatoes grown for
processing. Preplant. Broadcast.
Formulated with diphenamid.
Postemergence. Directed application. Use 0.75
Ib a.i. or less in areas receiving less than 20
inches average annual rainfall, and the entire
dosage range in areas receiving more than 20 in-
ches average annual rainfall. Use 0.75 Ib a.i.
or more on soils containing 2 to 5 percent organic
matter, and 1 Ib a.i. on soils containing 5 to 1C
percent organic matter. Apply after blocking or
thinning to the soil between the rows and beneath
the plantSi
.Pretransplant. Broadcast.
Pretransplant. Broadcast. Apply the lower dos-
age on sandy soils containing 2 to 5 percent or-
ganic matter and the higher dosage on sandy sells
containing 5 to 10 percent organic matter.
Pretransplant. Broadcast. Use 0.75 Ib a.i. or
less In areas receiving less than 20 inches aver-
age annual rainfall, and the entire dosage range
In areas receiving more than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on
soils containing 2 to 5 percent organic matter,
and 1 Ib a.i. on soils ccnt&iaiig : to 10 percent
organic matter.
0.05 ppm (N) (leafy vegetables)
Preplant. Broadcast.
grown for processing.
For use on turnip greens
Preplant. Broadcast. For use on turnip greens
grown for processing. Apply the lower dosage for
anticipated light weed pressure and the higher
dosage for anticipe'-ed heavy weed pressure.
1-036101-34
165
-------
/03009AA
/10008AA
Site, Dosage
and Formulation
(11':',•:. 1./A)
Walnut
0.5-1
(102 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
1-2
(10* G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
(4 Ib/gal EC)
(5 Ib/gal EC)
Watermelon
EPA Index to Pesticide Chemicals
TRJFLURALIN
Tolerance, Use, Limitations
,- '' :.<•-
: »; ' *»
0.05 ppm (N) (nuts)
Preplant. Broadcast. For use on new plantings
in areas receiving less than 20 inches average
annual rainfall. Use 0.75 Ib a.i. or more on fine
textured soils containing 2 to 5 percent orgeiic
matter, and 1 Ib a.i. on soils containing 5 to 10
percent organic matter.
Broadcast. For use on bearing or nonbearing,
established plantings in areas receiving less than
20 inches average annual rainfall.
Broadcast. For the control of rhizome Johnson-
grass on nonbearing and bearing, established
plantings in areas receiving less than 20 inches
average annual rainfall. Thoroughly work the soil
to bring rhizomes nearer the surface. Incorporate
to a depth of 4 to 6 inches. To control escaped
Johnsongrass, cultivate occasionally during grow-
ing season. Apply for 2 years in a row. Do not
use this dosage rate on new plantings. Do not in-
terplant with other crops. If treated areas are
diverted to other crop uses, plant only those
crops registered for preplant treatments of tri-
fluralin for the next cropping season.
Use limited to CA for the control of field bind-
weed. Subsurface Injection. Apply in the spring
using spray blades set to incorporate to a soil
depth of 4 to 6 inches in 40 to 80 gallons of
water per acre. Prior to application, destroy all
weeds. If soil develops cracks, eliminate by
shallow cultivating to prevent field bindweed from
emerging.
0:05 ppm (N) (cucurbits)
1.25-2.5 oz prod- Posteae gence. Broadcast. Apply to dry foliage
uct/100 sq.it vben plants have 3 to 4 true leaves.
(5Z G)
0.5-1
(5Z G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-64
Pestemergence. Directed application. Use 0.75
Ib e.i. or less in areas receiving less than 20
inches average «««ti*i rainfall, and the entire
dosage range in areas receiving more than 20 in-
ches average annual rainfall. Use 0.75 Ib a.i.
or more on soils containing 2 to 5 percent organic
1-036101-35
166
-------
/24007AA
Site, Dosage
and Formulation
(Ib a.i./A)
Watermelon (continued)
EPA Index to Pesticide Chemicals
TRIFLURAJLLN
Tolerance, Use, Limitations
Wheat
(winter)
0.75-1
(5Z G)
(10S G)
'(4 Ib/gal EC)
(5 Ib/gal EC)
0.75-1
(51 G)
(10Z G)
(4 Ib/gal EC)
(5 Ib/gal EC)
(spring, duram)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
0.5-0.75
(5Z G)
(101 G)
(4 Ib/gal EC)
(5 Ib/gal EC)
Issued: 4-17-84
matter, and 1 Ib a.i. on soils containing 5 to 10
percent organic matter. Apply to the soil be-
tween the rows and beneath plants which are in
the 3 to 4 true leaf stage. Set incorporation
equipment to throw treated soil around the plans
during incorporation.
0.05 ppm (N) (grain, straw)
General Information; Wheat planted in direct con-
tact with treated soil may suffer crop injury in
the form of delayed emergence and development.
Use limited to ID, MI, OR and WA for the control
of cheat and other weeds. Preplant. Broadcast.
Apply from 3 weeks up to planting. Incorporate
to a depth of 1 to 2 inches using a flex-tine
harrow. Do not till the soil with a disc after
incorporating with a flex-tine harrow. Plant
seed below the zone of treated soil.
Use limited to OR and WA. Preplant. Broadcast.
Apply to fallow land up to 4 months ahead of
planting from Hay to September. Incorporate to a
depth of 1 to 2 inches using a flexible tine-toot:
harrow. Do not till the soil with a disc after
incorporating with a flexible tine harrow. Plant
seed below the zone of treated soil.
Postplant. Broadcast. For the control of fox-
tail. Plant seed 2 to 3 inches deep in a well
tilled seedbed. Incorporate to a depth of 1 to
1.5 inches using a flex-tine or diamond harrow.
Both incorporations must be done within 24 hours.
Fall application for the control of foxtail.
Broadcast. Use a chisel plow (first pass only)
set to incorporate to a depth of 4 to 5 inches,
tandem disc set to Incorporate to a depth of 3 to
4 inches, or a field cultivator set to incorporate
to a depth of 3 to 4 Inches. Plant seed approxi-
mately 2 inches deep the following spring.
1-036101-36
167
-------
Site, Dosage
and Formulation
(Ib a.i./A)
Wheat (continued)
0.75-1
(5X G)
0.5-0.75
(5X G)
0.5-0.75
(4 Ib/gal EC)
(5 Ib/gal EC)
0.63-1
(101 G)
EPA Index to Pesticide Chemicals
' TRIFLURALIN
Tolerance, Use, Limitations
Use limited to ID, MN, ND, OR, SD, WA and WY for
the control of foxtail in summer fallow. Pre-
plant. Broadcast. Apply the lower dosage between
July 1 and August 31, and the higher dosage be-
tween April 15 and June 30. Use a chisel plow
(first pass only) set to incorporate to a depth
of A to 5 inches, tandem disc set to incorporate
to a depth of 3 to 4 inches, or a field cultivator
set to Incorporate to a depth of 3 to 4 inches.
Plant seed approximately 2 inches deep the fol-
lowing spring.
Use limited to ID, MN, ND, OR, SD, WA and VY.
Fall application for the control of foxtail.
Broadcast. Use a chisel plow (first pass only)
set to incorporate to a depth of A to 5 inches,
tandem disc set to incorporate to a depth of 3 to
4 Inches, or a field cultivator set to incorporate
to a depth of 3 to 4 inches. Plant seed approxi-
mately 2 inches deep the following spring.
Postplant. Broadcast. For the control of foxtail
and wild oat. Incorporate to a depth of 1 to 1.5
inches deep using flex-tine or diamond harrows.
Plant seed 2 to 3 inches deep in a well tilled
seedbed.
Tank mix with triallate.
For the control of foxtail in summer fallow. Pre-
plant. Broadcast. Apply the lower dosage in
August, 0.75 Ib a.i per acre In July, 0.88 Ib a.i.
per acre In June, and the higher dosage between
mid-April through May. Use a chisel plow (first
pass only) set to Incorporate to a depth of 4 to
5 inches, tandem disc set to Incorporate to a
depth of 3 to 4 inches, or a field cultivator set
to a depth of 3 to '4 inches. Plant seed approxi-
mately 2 inches deep the following spring.
Issued: 4-17-64
1-036101-37
168
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
TERRESTRIAL NON-FOOD CROP
(Ornamental Plants and Forest Trees)
General Warnings and Limitations; Application can be made broadcast
and soil incorporated, or as a surface application and watered into the
soil. Plantings should be well established prior to application. Make
applications when the foliage is dry, and water plants lightly to wash
the chemical from the leaves. Repeat applications can be made in 4 to
6 weeks for continued weed control. Do not apply to Ajuga, Dichoncra,
Myrtle or Pachysandra.
/31010AA Achillea
/31013AA Ag eraturn
/31023AA Arctotls
/31050AA Calendula
/3105LAA California Poppy
/31059AA Centaurea
/31076AA Coreopsis
/31077AA Cosmos
/31084AA Dahlias
/31087AA Planthus
/31091AA Dinorpbotheca
/31101AA Forget-Me-Nct
/31102AA Four 0'Clock
/31105AA Gaillardia
/31106AA Garden Balsam
/31121AA Hollyhock
/34077AA Iiora
/31133AA Lobelia
/31135AA Lupines
/31137AA Marigold
/31140AA Morning-Glory
/31143AA Nasturtium
/31286AA Nicotiana
/34109AA Peri via/, le
/31156AA Phlox
/31167AA Rose Moss .
/31169AA Rudbeckia
/31171AA Salvia
/31173AA Scabiosa
/31180AA Shasta Daisy
/31184AA Snapdragon
/31185AA Snow-On-The-Mountaia
/31188AA Stocks
/31194AA Sunflower
/31196AA Sweet Alyssum
/31197AA Sweet Pea
/31198AA
Sweet William
Issued: 4-17-64
1=036101-38
169
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage Tolerance, Use, Limitations
and ^emulation
Ub a.i./A)
Achillea cluster (continued)
1.25-2.5 02 Pretransplant. Broadcast. Apply and incorporate
product/100 sq.ft into the soil. Do not apply after transplanting.
(1.47: G)
0.15 oz a.il/100
sq.ft
(1.47: G)
(5S G)
1.25 Ib product/
100 sq.ft
(0.37X G)
0.15 oz a.i./lOO
sq.ft
(0.92X G)
2-4 oz product/
100 sq.ft
(0.93: G)
1.25-2.5 oz
product/100 sq.ft
(1.47: G)
2.13-2.84 oz
product/100 sq.ft
(1.75: G)
0.37-0.8 oz
product/100 sq.ft
(5: G)
0.5-1
(4 Ib/gal EC)
(1.75: PrD)
Broadcast. Surface application. Apply around
established plantings and water the treated area.
Broadcast. Apply and incorporate around estab-
lished plantings.
Directed spray. Apply and incorporate around es-
tablished plantings.
Directe-J spray. Apply to soil with bands 6 to 8
incnes apart at the rate of 2 to 3 feet per sec-
ond. Rake lightly into soil.
Issued: 4-17-84
1-036101-39
170
-------
Site, Dosage
and Formulation
(ib a.i./A)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
/3150CAA Adriatic Bellflower
/31303AA African Trailing
Daisy
/31423AA Agapanthus
/33C58AA Algerian Ivy (ground
cover)
/33086AA Big Blue Lilyturf
(ground cover)
/31502AA Blue Ceratostigma
/31405AA Chriscmas Cheer
/31498AA Common Thrift
/31076AA Coreopsis
/34045AA Cotoneaster
/34563AA Creeping Wireplant
/31437AA Crown Vetch
(Ornamental)
/33130AA Dwarf Coyotebrush
(ground cover)
/33030AA English Ivy
/33128AA Gazania
/31993AA Gazania sangelo
/31289AA Germander
/33139AA Goldmoss Sedun
/33138AA Hypericum coris
/33124AA Iceplant (ground
cover)
/31137AA Marigold
/33C38AA Mascarenegrass
/35289AA Myoporua
/35290AA Myoponim laetum
/34541AA Needlepoint Ivy
/33134AA Qsteospermum (ground
cover)
/33094AA Peruvian Verbena
, (ground cover)
/33137AA Point Reyes Ceanothus
/31302AA Rockrose
/33120AA Rosemary (ground
ccver ;•
/315C3AA Rupturewort
/3312$AA Sedun
/33140AA Sedua confusum
/31994AA Sedun musaneuse
/31501AA Serbian Bellflover
/34209AA Shrub-Althea
/31268AA Snov-In-Suamer
/31419AA Sprenger Asparagus
/33126AA St. John'«-Wort
(ground cover)
Issued: A-17-84
1-036101-40
171
-------
Site, Dosage
and formulation
EPA Index to Pesticide Chemicals
TRIFLURAUN
Tolerance, Use. Limitations
/33106AA
/31455AA
/31206AA
/31207AA
/31499AA
/35094AA
/35024AA
/35025AA
/35026AA
/34025AA
/35030AA
/35031AA
/35032AA
/35033AA
/34031AA
/34035AA
/35384AA
/34243AA
/35235AA
/35155AA
/31067AA
/34043AA
/34405AA
/35133AA
/34244AA
/34050AA
/35044AA
/35045AA
/3445QAA
/34991AA
/35172AA
Adriatic Bellflower cluster (continued)
Stravberry (Ornament-
al) (ground cover)
Treasure Flower
Verbena
Veronica
Woolly Yarrov
0.15 oz a.i./lOO
sq.ft
(5S G)
0.15 oz a.i./lOO
sq.ft
(51 G)
0.15 oz a.i./lOO
sq.ft
(4 Ib/gal.EC)
Apple
Austrian Pine
Baldcypress
Balsam Fir
Barberry
Black Locust
Black Walnut
Blackgun
Blue Spruce
Boxwood
California Privet
Carolina Cherry-
Laurel
Cherryberry Coton-
easter
Chinese Chestnut .
Chinese Juniper
Cinquefoil
Common Camellia
Common Lilac (Alba)
Co ttonwood
Cranberry Cotoneaster
Deutzia
Douglaa-Fir
Eastern Hemlock
Erect Euonymus
Euonymus Newport
European White Birch
Issued: 4-17-84
Pretransplant. Broadcast,
Water into soil.
Surface application.
Broadcast. Surface application. Apply around
established plantings and water into soil.
Broadcast. Apply and water incorporate with oce-
half inch of water within 24 hours after applica-
tion to established plantings.
1-036101^41
172
-------
EPA Index to Pesticide Chemicals
TRJFLURALIN
Site, Dosage
and .-Jfcoraulfi t. i or.
'
Tolerance, Use, LiIDitations
»•• /) '•*:.
Apple cluster (continued)
/.34058AA Firethora
735C57AA Flowering Dogwood
/34181AA Golden Bell
/34246AA Harlands Boxwood
/34304AA ' Hetzi Holly
7.34372AA Hiryu Azalea
/35070AA Honeylocust
734072AA Honeysuckle
734075AA India Hawthorn
734185AA Indica Azalea
735181AA Intermediate Yew
734078AA Japanese Andromeda
734079AA Japanese Barberry
735185AA Japanese Black Pine
735244AA Japanese Dogwood
734080AA Japanese Holly
/35186AA Japanese Larch
/34310AA Japanese Pittosporum
/34188AA Japanese Privet
/35072AA Japanese Yew
734429AA Littleleaf Borvood
735076AA Loblony Pine
735192AA London Plane
734094AA Mock-Orange
/34097AA Mountain-Laurel
735092AA Northern White-Cedar
/35089AA Norvay Maple
735090AA Norway Spruce
735255AA Pin Oak
/34112AA Pineapple Guava
/35102AA Prunus
/35204AA Red Maple
/35105AA Red Oak
/35106AA Red Pine
/35103AA Redbud
, /35104AA Redcedar
/34208AA Sakaki
/34122AA Sandankwa Viburnum
734124AA Sasanqua Camellia
/35206AA Scarlet Oak
/35113AA Scotch Pine
/35209AA Shore Juniper
/35211AA Silver Maple
/35117AA Sugar Maple
/34133AA Sweet Viburnum
/35118AA Sveetgum
/35119AA Sycamore
Issued: 4-17-64
I-O36101-42
173
-------
734218AA
/35120AA
734223AA
/34258AA
734224AA
/35227AA
/35126AA
735127AA
73512 8AA
734232AA
734074AA
735253AA
731026AA
731057AA
731134AA
731213AA
Site, Dosage
and Formulation
(Ib a.i./A)
Apple cluster (continuec;
Thorny Elaeagnus
Tuliptree
Vanhoutce Spirea
Viburnum Doublefile
Weigela Bristol Ruby
White Aah
White Pine
White Spruce
Willov
Winged Euonymus
Wright Viburnum
Yew Podocarpus
EFA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
0.37-0.8 oz
product/100 sq.ft incorporation.
(5: G)
Pretransplant or posttransplant. Broadcast. Sell
0.15 oz a.i.7100
sq.ft
(51 G)
0.15 oz a.i.7100
sq.ft
(55 G)
0.5-1
(4 Ib/gal EC>
0.5-1
(4 Ib/gal EC)
Aster
Carnation
Petunias
Zinnia
1.25-2.5 oz
Pretransplant. Broadcast. Surface application.
Water into soil.
Broadcast. Surface application. Apply around
established plantings and water into soil.
Pretransplant. Broadcast. Apply and incorporate
prior to planting.
OR
Directed spray. Apply and incorporate around es-
tablished plantings.
Pretransplant. Broadcast. Apply and incorporate
product/100 sq.ft isto the soil. Do not apply after transplanting.
(1.47Z G)
Issued: 4-17-84
1-036101-43
f-74
-------
Site, Dosage
and Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
lb a.i'. /Ay
Aster cluster (continued)
2 lb product/100
sq.ft
(0.0952 G)
0.15 oz a.i./lOO
sq.ft
(1.472 G)
CSS. G)
•
1.25 lb product/
100 sq.ft
(0.372 G)
2-4 oz product/
100 sq.ft
(0.932 G)
1.25-2.5 oz
product/100 sq.ft
(1.472 G)
2.13-2.84 oz
product/100 sq.ft
(1.752 G)
0.37-0.8 oz
product/100 sq.ft
(52 G)
0.15 oz a.i./lOO
sq.ft
(0.92S G)
(1.152 G)
0.5-1
(4 Ib/gal EC)
(1.752 PrD)
Broadcast. Apply and incorporate around estab-
lished plants. Water the treated area and repeat
treatment every 6 weeks. Do not use on newly
seeded or planted flower beds.
Formulated with di-systoc.
Broadcast. Surface application. Apply around
established plantings and water the treated area.
Broadcast. Apply and incorporate around estab-
lished plantings.
Directed spray. Apply and incorporate around es-
tablish .d plantings.
Directed spray. Apply to soil with bands 6 to 8
Inches apart at the rate of 2 to 3 feet per sec-
ond. Rake lightly into soil.
Issued: 4-17-84
1-036101-44
175
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage Tolerance, Use, Limitations
and Simulation
(Ib a.l./A)
/ 3- 50 C AA Azalea Hybrids/Culti-
vars
1.88-2.5 Ib Broadcast. Apply uniformly around established
product/100 sq.ft plants starting 4 inches from base. Incorporate
(0.0932 G) lightly into soil and repeat every 6 weeks.
Formulated with di-syston.
9.6-10 oz product/ Broadcast. Apply and incorporate around estab-
100 sq.ft lished plantings.
(0.74Z G)
0.15 oz a.i./lOO
sq.ft
(0.92: G)
/31065AA Qirysanthemua
1*25-2.5 oz Pretransplaat. Broadcast. Apply and incorporate
product/100 sq.ft into the soil. Do not apply after transplanting.
(1.47: G)
2 Ib product /100 Broadcast. Apply and incorporate around estab-
sq.ft lished plantings and incorporate to a depth of 1
(0.0951 G) to 2 inches. Water the treated area and repeat
treatment every 6 weeks. Do not use on newly
seeded or planted flower beds.
Formulated with di-syston.
0.15 oz a.i./lOO Broadcast. Surface application. Apply around
sq.ft established plantings and water the treated area.
(1.47: G)
G)
2-4 oz product/ Broadcast. Apply and incorporate around estab-
100 sq.ft lished pls-tiiigE.
(0.93: G) ...
1.25-2.5 oz
product/100 sq.ft
(1.471 G)
0.37-0.8 oz
product/100 sq.ft
(51 G)
0.5-1 Directed spray. Apply and incorporate around es-
(4 Ib/gal EC) tablished plantings.
Issued: 4-17-84 1-036101-45
176
-------
/31083AA
/31025AA
/35043AA
/31111AA
Site, Dosage
and Formulation
(Ib a.i./A;
Chrvsanthemum (continued)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Directed spray. Apply to soil with bands 6 to 6
inches apart at the rate of 2 to 3 feer per
ond. Rake lightly into soil.
2.13-2.84 oz
Broadcast. • Apply and incorporate around
product/100 sq.ft lished plantings.
(1.75: G)
10 oz product/100 Broadcast. Apply and incorporate around esu:-
sq.ft
(0.742 G)
Gladiolus
1.25-2.5 oz
lished plantings.
General Information; Conns.less than 1 inch 'n
diameter may be Injured by preplan: applies:. .zs.
Pretransplant. Broadcast. Apply and incorporate
product/100 sq.ft into the soil. Do not apply after transple: :iag.
(1.472 G)
0.37-0.8 oz
product/100 sq.ft
(52 G)
0.5-1
(4 Ib/gal EC)
2-2.5 Ib product/ Broadcast. Apply around established plantings and
100 gq.ft
(0.172 G)
(0.1742 G)
0.15 oz a.i./lX
sq.ft
(1.472 G)
(52 G)
1.25 Ib product/
100 sq.ft
(0.372 G)
Issued: 4-17-84
incorporate to a depth of 1 inch. Water :.:
treated area and repeat treatment in 4 wtt^s. Do
not use when planting from seed.
Formulated with di-syston.
Broadcast. Surface application. Apply Oio—
established plantings and water tht tre^:ei .-. :ee.
Broadcast. Apply and incorporate around estab-
lished plantings.
1-036101-46
177
-------
Site, Dosage
and .Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
/34089AA
/35000AA
Gladiolus (continued)
1.25-2.5 oz
product/100 sq.ft
(1.47Z G)
2.13-2.84 oz
product/100 sq.ft
(1.75: G)
0.37-0.8 oz
product/100 sq^ft
(51 G)
0.15 oz a.i./lOO
sq.ft
(0.921 G)
(1.15X G)
0.5-1
(4 Ib/gal EC)
(1.75: PrD)
Lilac
1.88-2.5 Ib
product/100 sq.ft
(0.095S G)
Ornamental and/or
Shade Trees
0.37-0.8 02
product/100 sq.ft
(51 G)
1.25 Ib product/
100 sq.ft
(0.37Z G)
2-4 02 product/
100 sq.ft
(0.93Z G)
Issued: 4-17-84
Directed spray. Apply and Incorporate around es-
tablished plantings.
Directed spray, Apply to soil with bands 6 to 8
inches apart at the rate of 2 to 3 feet per sec-
ond. Rake lightly into soil.
Broadcast. Apply uniformly around established
plants starting 4 inches from base. Incorporate
lightly Into soil and repeat every 6 weeks.
Formulated with dl-syston.
Pretransplant. Broadcast. Apply and incorporate
into the soil. Do not apply after transplanting.
Broadcast. Apply and incorporate around estab-
lished plantings.
1-036101-47
178
-------
/34004AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
Tolerance, Use, Li,?..-*tations
Site, Dosage
angj&o rm ula t i on
(lb*a.i./A) •-• -"-"
Ornamental Flowering Plants (continued)
Broadcast. Surface application. Apply around
established plantings and water the treatec area.
Broadcast. Apply and incorporate around
established plantings.
0.15 02 a.i./lOO
sq.ft
(52 G)
0.15 oz a.i./lOO
sq.ft
(1.15S G)
1 cup product (by
volume)/100 sq.ft
(2.652 G)
0.37-0.8 oz
product/100 sq.ft
(51 G)
Ornamental Woody
Shrubs
0.37-0.8 oz Pretransplant. Broadcast. Apply and incorporate
product/100 sq.ft into the soil. Do not apply after transplanting.
(52 G)
2.5-3.13 Ib Broadcast.' Apply and incorporate around estab-
product/100 sq.ft lished plants and water the treated area.
(0.172 G)
(0.1742 G)
0.15 oz a.i./lOO
sq.ft
(1.472 G)
(52 G)
1.25 Ib product/
100 sq.ft
(0.372 G)
2-4 oz product/
100 sq.ft
(0.932 G)
1.25-2.5 oz
product/100 sq.ft
(1.471 G)
Formulated with di-syston.
Broadcast. Surface application. Apply around
established plantings and water the treated area.
Broadcast. Apply and incorporate around estab-
lished plantings.
Issued: 4-17-64
1-036101-50
179
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Site, Dosage
and Formulation
(Ib a.i./A)
/3i007AA Ornamental Deciduous
Shrubs
/35006AA Ornamental Deciduous
Trees
/330C9AA Ornamental Ground
Covers
4.5 cups product
(by volume)/100
sq.ft
or
3.75 cups product
(by volume)/
10 ft drip zone
diameter
(0.682 G)
/320C5AA . Ornamental Evergreens
1.88-2.5 Ib
product/100 sq.ft
(0.0952 G)
Tolerance, Use, Limitations
'—. * j£k
Broadcast. Apply around established plantings an:
repeat in 2 to 3 months. Incorporate to a depth
of 1 inch and water the treated area. For year
round control, a third treatment may be made in
mid-fall.
4.5 cups product
(by volume)/100
sq.ft
or
3.75 cups product
(by volume)/
10 ft dripzone
diameter
(0.682 G)
9.6-10 oz product/
100 sq.ft
(0.742 G)
0.15 oz a.i./lOO
sq.ft
(0.922 G)
(1.152 G)
/31003AA Ornamental Flovering
Plants
2-2.5 Ib product/
100 sq.ft
(0.171 G)
(0.1742 G)
Issued: s-17-84
Broadcast. Apply around established plants start-
ing 4 inches from base. Incorporate lightly into
soil and repeat every 6 weeks.
Formulated with di-syston.
Broadcast. Apply around established plantings an:
repeat in 2 to 3 months. Incorporate to a depth
of 1 inch and water the treated area. For year
round control, a third treatment may be made in
mid-fall.
Broadcast. Apply and incorporate around estab-
lished plantings.
Broadcast. Apply around established plantings and
incorporate to a depth of 1 inch. Water the
treated area and repeat treatment in 4 to 6
weeks. Do not use when planting from seed.
Formulated with di-syston.
1-036101-49
-------
/3100.5M
EPA Index to Pesticide Chemicals
TRIFLUBALIN
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
Ornamental and/or Shade Trees (continued)
1.25-2.5 02
product/100 sq.ft
(1.472 G)
2.13-2.84 oz
product/100 sq.ft
(1.752 G)
1 cup product (by
volume)/100 sq.ft
(2.652 G)
0.37-0.8 oz
product/100 sq.ft
(52 G)
0.15 oz a.i./lOO
sq.ft
(0.92Z G)
(1.151 G)
0.15 oz a.i./lOO
sq.ft
(1.472 G)
(52 G)
(1.751 PrD)
Ornamental Bulb
Plants
Broadcast. Surface application. Apply around
established plantings and water the treated area.
Directed spray. Apply to soil with bands 6 tc 6
inches apart at the rate of 2 to 3 feet per sec-
ond. Rake lightly into soil.
2-2.5 Ib product/ Broadcast. Apply around established plantings and
100 sq.ft
(0.172 G)
(0.174: G;
incorporate to a depth of 1 inch. Water the
treated area and repeat treatment in 4 to 6 weeks.
Formulated with di-syston.
Issued: 4-17-84
1-036101-48
•181
-------
/34118AA
/34120AA
Site, Dosage
and formulation
(Ib a.i./A)
Ornamental Woody Shrubs (continued)
2.13-2.84 oz
product/100 sq.ft
(1.751 G)
1 cup product (by
volume)/100 sq.ft
(2.652 G)
0.37-0.8 oz
product/100 sq.ft
(51 G)
0.15 oz a.i./lOO
sq.ft
(0.922 G)
(1.152 G)
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
(1.752 PrD)
Rhododendron Hybrids/
Cultivars
Directed spray. Apply to soil with bands 6 to 6
inches apart at the rate of 2 to 3 feet per sec-
ond. Rake lightly into soil.
1.88-2.5 Ib Broadcast. Apply around established plants start-
product /100 sq.ft ing 4 inches from base. Incorporate lightly into
(0.0952 G)
soil and repeat every 6 weeks.
Formulated with di-syston.
10 oz product/100 Broadcast. Apply and incorporate around estab-
sq.ft
(0.74J G)
0.15 oz a.i./lOO
sq.ft
(0.922 G)
lished plantings.
Rose
2 oz product/plant Broadcast. Apply and incorporate around estab-
(0.0952 G) lished plants. Water Che treated area and repeat
treatment at 6 week intervals.
Formulated with di-syston.
Issued: 4-17-84
1-036101-51
182
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Site, Dosage
and Formulation
(ib a.i./A)
Rose (continued)
4 oz product/plant Broadcast. Apply and incorporate around esta'r-
(0.17* G) lished or newly transplanted rose bushes. Water
(0.174Z G) the treated area and repeat treatment at 4 to 6
week intervals. Do not apply directly into
planting hole.
Formulated with di-syston.
0.15 02 a.i./lOO
sq.ft
(1.47: G)
(5% G)
1.25 Ib product/
100 sq.ft
(0.371 G)
2-4 02 product/100
sq.ft
(0.931 G)
1.25-2.5 02
product/100 sq.ft
(1.471 G)
0.37-0.8 02
product/100 sq.ft
(51 G)
0.15 oz a.i./lOO
sq.ft
(0.92Z G)
(1.151 G)
0.5-1
(4 Ib/gal EC)
(1.751 PrS)
Broadcast. Surface application. Apply around
established plantings and water the treated area.
Broadcast. Apply and incorporate around estab-
lished plantings..
Directed spray. Apply and incorporate around es-
tablished plantings.
»
Directed spray. Apply to soil wltl bands 6 to 8
inches apart at the rate of 2 to 3 iest per sec-
ond. Rake lightly into soil.
Issued: 4-17-84
1-036101-52
183
-------
Site, Dosage
and formulation
/670010A
/67015GA
/67004QA
/670130A
/67009QA
/670110A
/670050A
/670060A
/650130A
/670040A
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
(Noncrop, Wide Area, And General Outdoor Treatments)
Airport Runways :
Fencerows (Non-
agricultural)
Firebreaks
4-8
(AS G)
Highway Rlghts-of-Way
Broadcast. Surface application.
Formulated with tebuthiuron.
General Information; Highway Rights-of-Way in-
clude areas around guardrails, signposts, markers
and road shoulders.
.Refer to Airport Runways cluster for use and
limitation Information.
/670090A
Industrial.Sites
/670110A
Paved Surfaces
12-16
(4 Ib/gal EC)
or
0.2?-:.3£ Ib a.i.
1,000 sq.ft
(4 Ib/gal EC)
General Information: Industrial Sites include
areas around buildings, lumberyards and tank
farms.
Refer to Airport Runways cluster for use and
limitation information.
Preparing application. Prepare soil surface ac-
cording Co good construction practices. If rhi-
zomes, stolons, tubers or other vegetative plant
parts are present, remove by scraping with a grad-
er' blade. Do not move soil following an applica-
tion, and do not apply to areas where asphalt is
to be layed directly on top of soil. Apply in a
minimum of 130 gallons of water per acre.
Refer to Airport Runways cluster for additional
use and limitation Information.
Issued: 4-17-84
1-036101-53
184
-------
/67C35CA
/670060A
Site, Dosage
and.Formulation
EPA Index to Pesticide Chemicals
TRIFLURALIN
Tolerance, Use, Limitations
Railroad Rights-of-
Way General Information: Railroad Rights-of-Way i:
elude areas around ballast, yards and rcadber's,
Refer to Airport Runways cluster for use and
limitation information.
Utility Rights-of-Way
General Information; Utility Rights-of-Way iv.-
clude areas around substations, transmission
towers, and poles.
Refer to Airport Runways cluster for use and
limitation information.
/650130A
AQUATIC NON-FOOD
(Aquatic Sites)
Ditchbanks
Refer to TERRESTRIAL NON-FOOD CROP, Airport
Runways cluster for use and limitation info:
tion.
9001500
AAAAAAA
9900300
AAAAAAA
AERIAL AND TANK MIX APPLICATIONS
Aerial Application
Tank Mix
Issued: 4-17-84
Refer to
TERESTRIAL FOOD CROP
(Agricultural Crops)
All sites
r.efer to
TERESTRIAL FOOD CROP
(Agricultural Crops)
Barley, Beans (Dried Type), Cotton, Corn, Peas,
Peas (English), Peanuts, Potato, Sorghum, Soy-
beans, Sugar Beets, Sunflower, Wheat
1-036101-54
185
-------
EPA.Index to Pesticide Chemicals
TRIFLURALIN
Listing of Registered Pesticide Products by Formulation
93* technical chemical u. f> :>&
triiluralin ^036101; "^^
001471-00070
£.097.0001 97T. technical chemical
trifiuralin (036101)
OG2749-00294 019713-00109 033660-00003
0,096.OOC1 98% technical chemical
triiluralin (036101)
011603-00013
&24i..50C2 44.5* formulation intermediate
trifiuralin (036101)
001471-00072
&246.00C2 46S formulation intermediate
trifiuralin (036101)
011603-00014
aC-GO.0954 0.0951 granular
trifiuralin (036101) plus 0,0-diethyl s-[ 2-<,ethyithio)ethyi]phosphcro-
dithioate (032501)
005887-00062
•
iOOO.1704 0.17; granular
trifiuralin (036101) plus 0,0-diethyl s-[2-(ethylthio)ethyl]phosphoro-
dithioate (032501)
006993-00029 042057-00078
&000.1744 0.174S granular
trifiuralin (036101) plus 0,0-diethyl s-[2-(ethylthio)ethyl]phosphorc-
dithioate (032501)
000239-02292
iOOO.2004 0.21 granular
trifiuralin (036101)
006735-00228
5,000.2504 0.25S granular -
trifiuralin (036101)
0:6735-00236
f~
iOOO.3504 0.35? granular
trifiuralin (036101)
006735-00233
&000.3704 0.37S granular
trifiuralin (036101)
000239-02262
Issued: 4-17-84 1-036101-55
186
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Listing of Registered Pesticide Products by Formulation (continued)
0.5°" granular
trifluralin (036101)
006735-00234
iOCO.6804 0.68% granular
trifluralin (036101)
000538-00083
6.000.7404 0.743; granular
trifluralin (036101)
000239-02263 000961-00283
i000.920i 0.92% granular
trifluralin (036101)
000572-00226 000572-00260
aOOO'.9304 0.932 granular
' trifluralin (036101)
001598-00215
-------
iOlC.0006
al05.0Cl2
&OC1.752C
9999999
EPA Index to Pesticide Chemicals
TRIFLURAUN
Listing of Registered Pesticide Products by Formulation (continued,
3.1% wettabie povder
trifluraiin i036101)
001471-00135
10~ wettabie powder
trifiuralin (036101) plus diphenamid (036601)
001471-00136
1.5 Ib/gal emulsifiable concentrate
trifiuralin (036101) plus oryzalin (104201)
001471-00137
4 Ib/gal emulsifiable concentrate
trifiuralin (036101)
001386-00609 001471-00035 001471-00065
002749-00219 005481-00172 006735-00215
034704-00241 034704-00242 044215-00073
5 Ib/gal emulsifiable concentrate
trifiuralin (036101)
001471-00120
1.75* pressurized dust
trifiuralin (036101)
004822-00123
001471-00116
007001-00193
044215-00106
State Label Registrations
006735-05531 006735-05535 038749-10311
010583-09353
037847-08316 037863-08155
008278^09246 011093-07125
037800-08387 037914-09443
Al Reg. No.
006735-05530
AZ Reg. No. .
010163-06401
AR Reg. No.
037821-08429
CA Reg. No.
002935-06591
GA Reg. No.
037800-08386
LA Reg. No.
006735-04835
006735-04843
NM Reg. No.
010583-03260
Issued: 4-17-84
006735-04836
006735-04844
006735-04840 006735-04841
1-036101-57
188
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Listing of Registered Pesticide Products by Formulation (continued)
NY Reg. No.
.,38655-10443
NC Reg. No.
039863-10573
TX Reg. No.
006735-04816 006735-04618 010563-08653
Issued: 4-17-84 1-036101-58
189
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix A
Listing of Common Chemical Names Used on the Entry
Chemical
Code
032501
041401
041404
078801
078802
101101
Common Name
(source)
Di-Syston
Eptam
vernolate
diallate
triallate
metribuzin
EPA Acceptable
Common/Chemical Name
0,0-Diethyl S-[2-(ethyithio)ethyij
phosphorodithioate
S-Ethyl dipropylthiocerbamate
S-Propyl dipropylthiocarbamate
S-(2,3-Dichloroallyl) iiisop:?-
pylthiocarbamate
S-(2,3,3-Trichloroallyi) diiscpro-
pylthiocarbamate
4-Amino-$-(l,l-dimerh; lethyl •-
3-(methylthio)-l,2,4-trizin-
5(4H)-one
Issued: 4-17-84
1-036101-59
190
-------
PA—AAAC
PBGACS5
PEMAiBE
PBDAEAA
PCOAF5A
PEAAGAC
PBDAIBA
PBDAIAB
PAAAABI
PAfACBC
PFMAFBB
PAAAABP
PAIACBI
PAFACAB
PBDAKBA
PEAAGAD
PAFACBJ
PBYAGBK.
PFGAZBA
EPA Index to Pesticide Checicals
TRIFLURALIN
Appendix B
bv Site/Pest and Site/Formulatio-4'?' ,&stration Numbei
'; „ *V~'?.-^C •"•*•
BROADLEAF WEEDS CONTROLLED; '"
-------
PCAARAA
PCABFLD
PCABYAA
PCABKBC
PCACEBL
PCABLSB
PCACUBD"
EFA index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Lis-.ing by Sice/Fest ;.nd Site/Formuj^tie
GRASSES AND CTHET-. X3.. . JOTS CONTROLLED
Shattercane
Signalgrass
Smooth crabgrass
Sprangletop
Stinkgrass
Texas panicus
Woolly cupgrass
Yellow foxtail
ion Nu=v r (zc.-r.-i
/230C1AA
/03001AA
/050C1AA
TERRESTRIAL FOOD CRCF
(Agricultural Crops)
Alfalfa
Pests (see list abcve)
G)
001471
001^71-00035
034704-00241
(10S G)
001471-00143
(4 Ib/gal EC!
001386-00609
006735-OC215
044215-0C1G6
(5 Ib/gal EC)
001471-00120
Almond
Pests (see list above)
(101 G)
001471-00143
001471-00116
034704-00242
OC2749-00219
044215-00073
(4 Ib/gal 2:.
001386-:, .6.
(5 Ib/gal EC)
001471-c:;.
Apricot
Pests (see list above)
(10X G)
001471-00143
Issued: 4-17-64
JC1471-OOC35 001471-00116 034704-OC241
1-036101-61
192
-------
/16002AA
/28063AA
• /15001AA
/1500LAA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix 8
Listing by Site/Pest and Site/Fonnulation/Regi.c.r.-f.tion Number (continue-:
Apricot (continued) •-''
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116 034704-00241
(5 Ib/gal EC)
0014/1-00120
Asparagus
Pests (see list above)
(4 Ib/gal EC)
001471-00035 001471-00116
(5 Ib/gal EC)
001471-00120
Barley
Pests (see list above)
(55 G)
001471-00059 001471-00125
(105 G)
001471-00143
001471-00116
(4 Ib/gal EC)
001471-00035
(5 Ib/gal EC)
001471-00120
Beans, Adzuki
Pests (see list above)
CSS G)
001471-00059 001471-00125
(4 Ib/gal EC)
001471-00035 001471-00116
(5 li-/gai EC)
001471-00120
Beans, Dried-Type
Pests (see list above)
(0.2: G)
006735-00228
(0.25Z G)
006735-00236
Issued: 4-17-84
1-036101-^2
193
-------
/150G2AA
EPA Index to Pesticide Chemicals
. TRIFLURALIN
Appendix B
Lisf'ng by Site/Pest and Site/Formula.f.ion/Registration Number (continue:
Beans, Dried-Type (continued)
U.75S G)
000961^)0335
(5J G)
000226-00252
(102 G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
(5 Ib/gal EC)
001471-00120
Beans, Lima
Pests (see list above)
(0.2* G)
006735-00228
(0.25S G)
006735-00236
(0.93X G)
001598-00215
001471-00059 001471-00125
001471-00035 001471-00116 002749-00219
(1.47X G)
000961-00280
043640-00001
(1.751 G)
000961-00335
(5S G)
000226-00252
(10Z G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Issued: 4-17-84
002217-00480 007401-00349 009198-00060
001471-00059 009499-00004
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
1-036101-63
194
-------
713005AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continue:
Beans, Snap
Pests (see list above)
(C.2~ G)
006735-0022S
(0.25S G)
006735-OG236
(0.93% G)
001598-00215
001471-00035
034704-00241
U.47S G)
000961-OC280
043640-00001
(1.75: G)
000961-00335
(5X G)
000226-00252
(102 G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)'
001471-00120
Broccoli
Pests (see list above)
(direct seeded)
(0.2* G)
006733-CC226
(0.25Z G)
006735-00236
(0.93S G)
001598-00215
OC2217-00480 007401-00349 OOS198-00060
001471-00059 009499-00004
001471-00116
034704-00242
002749-00219
044215-00073
(1.471 G)
000961-00280
009198-00060
Issued: 4-17-84
001159-00202
0^3640-00001
002217-00480 007401-003A9
1-036101-64
195
-------
EPA Index to Pesticide Chemicals
TRJFLURALIN
Appendix B
Listing by Site/Pest and Site/Formuiation/Registration Number (continue:
Broccoli (continued)
U.75i G)
000961-00335
(5: G)
000226-00252
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
(transplants)
(0.2S G)
006735-00228
(0.25: (i)
006735-00236
(0.93X G)
001598-00215
(1.47S G)
000961-00280
009198-00060
(1.75J G)
000961-00335
(51 G)
000226-00252
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Issued: 4-17-84
001471-00059 009499-00004
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
001159-00202
043640-00001
002217^)0480 007401-00349
00147L-00059 009499-00004
001471-00035
C34704-00241
001471-00116
034704-00242
002749-00219
044215-00073
1-036101-65
196
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Lir.i-xng bv Site/P»st -...r:d Site/Formulatic^-v. .-lustration Number (continued'!
itf ' ' * *••£?£•*&
713006AA Brussels Sprouts
Pests (see list above)
(direct seeded;
(0.22 G)
006735-00228
(0.252 G)
006735-00236
(0.932 G)
001598-00215
•v ,) V
(1.471 G)
000961-00260
009198-00060
(1.752 G)
000961-00335
(52 G) •
000226-00252
(102 G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
(transplants)
(0.22 G)
006735-00228
(0.252 G)
006735-00236
(0.932 G)
001598-00215
(1.472 G)
0009.61-00280
009198-00060
(1.752 G)
000961-00335
Issued: 4-17-84
001159-00202
043640-00001
002217-00480 007401-00349
001471-00059 009499-00004
001471-00035
034704-00241
001471-00116 002749-00219
034704-00242 ' 044215-00073
001159-00202
043640-00001
002217-00480 007401-00349
1-036101-^6
197
-------
/130C7AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Foroulajtioc ''.' -ci^-Cation
Brussels Sprouts (co_;inued) '='',', '/v
-------
/10002AA
EPA Index to Pesticide Clericals
TRIFLURAUN
Appendix B
Listing by Site/Pest and Site/Formulation/F.eg-;--ration Number (continue:
*. •*•' u.
Cabbage (continued) '•'-•'"
(transplants)
(0.2S G)
006735-00228
(0.25% G)
006735-00236
(0.93% G)
• 001598-00215
001159-00202
043640-00001
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000961-00335
(5i G)
000226-00252
(102 G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Cantaloupe
Pests (see list above)
(1.472 G)
C<: 115 9-0 02 02 002217-00480
002217-00480 007401-00349
001471-00059 009499-00004
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
009198-OOOt.
(52 G)
001471-00059
(101 G) '.
001471-00143
(4 Ib/gal EC)
001386-00609
034704-00242
Issued: 4-17-84
009499-00004
001471-00035
044215-00073
001471-00116
044215-00106
034704-00241
1-036101-68
199
-------
/27GC1AA
Z?A Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest ar.c Site/Formulatipn/Registration Number (cc:
Cantaloupe (continued)
(5 Ib/gai EC)
OG1471-OG120
Carrot
Pests (see list ab-:ve)
(0.2% G)
006735-00228
(0.25* G)
006735-00236
(0.932 G)
001598-00215
001159-00202
045640-00001
001-71-00035
034704-00241
(1.472 G)
000961-00280
009198-00060
(52 G)
009499-00004
(4 Ib/gai EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Castor Bean
Pests (see list above)
(52 G)
001471-00059
(102 G)
001471-00143
002217-00480 007401-00349
001471-00116
034704-00242
002749-00219
044215-00073
(4 Ib/gal EC)
001386-00609
(5 Ib/gal EC)
001471-00120
001*71-00035 ' 001471-00116
Issued: 4-17-84
1-036101-69
200
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continued., ...
Cauliflower
Pests (see list above)
'.direct seedec)
(0.2% G)
(0.25i G)
00(725-00236
(0.9.-S 0)
001598-00215
(1.47S G)
OC-.3e:-:C280 001159-00202 002217-00480 007401-003^*
009198-00060 043640-00001
(1.751 G)
I5i G)
000226-C0252 001471-00059 009499-00004
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116 002749-0021?
0067?5-00215 034704-00241 034704-00242 044215-00073
(5 Ib/gal EC)
001471-00120
(transplants)
(0.2S G)
006735-OC228
(0.2r: :
(0.93S G)
001596-00215
(1.4'S •--.'
0&.9c.-v02hO 001159-00202 002217-00480 007401-003^9
OO.-lS-i-yd&iO 043640-00001
(1.75X G)
Issued: 4-17-c4 1-036101-70
201 ..
-------
/13002AA
/02000AA
/13009AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulatioc/Registratioc Number (co
Cauliflower (continued)
nt-nuec
(5
OOG226-00252
001471-00059 009499-00004
001471-00035
034704-00241
001471-00116
034704-00242
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Celery
Pests (see list above)
(direct seeded and transplant)
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116
034704-00242 044215-00073 044215-00106
(5 Ib/gal EC)
001471-00120
Citrus Fruits
Pests (see list above)
(51 G)
001471-00059
(101 G)
001471-00143
002749-00219
044215-00073
034704-00241
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Collards
Fests (see list above)
(0.21 G)
006735-00228
(0.25Z G)
006735-00236
Issued: 4-17-84
001471-00116
034704-00242
002749-00219
044215-00073
1-036101-71
202
-------
E?A Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulatior^sr. castration Nunber (continued.
Collards (ccati:
stjlag by Site/Pest and Site/Formulatior^sf. castration Nunber (continu
lollards (continue;; **" A"';
(A Ib/gal EC)
001386-00609 001471-00035 001471-00116 002749-00219
006735-00215 0347C--OC241 034704-OC242 044215-00073
044215^)0106
(5 Ib/gal EC)
001471-00120
/280C7AA Cotton
Pests (see list above)
(0.21 G)
006735-00226
(0:25S G)
006735-00236
(0.35S G)
006735-00233
(0.5S G)
006735-00234
(51 G)
001471-00059
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116 002749-00219
006735-00215 034704-00241 034704-00242 044215-00073
044215-00106
(5 Ib/gal EC)
001471-00120
/28005AA Corn
Pests (see list above)
(4 Ib/gal EC)
001471-OOC35 OCl-r:-.
(5 Ib/gal EC)
001471-00120
Issued: 4-17-84 1-036101-72
203
\ ^
-------
/' 2SCG6AA
/10010AA
/28009AA
/01014AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
List-',-.- bv Site/Pest ar.::. S ite/ Formula ^02 _-•'
- ' ^ " ' ;,
Corr., Field
Pests (see list above)
(4 Ib/gal EC)
OG1471-OOC35 001471-00116
(5 Ib/gal EC)
001471-00120
Cucumber
ioz Nurbe . (cont.ir.-je::,
Pests (see list above)
(1.47Z G)
001159-00202 002217-00480
009198-00060
009499-00004
001471-00035
044215-00073
(X G)
. 001471-00059
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609
034704-00242
(5 Ib/gal EC)
001471-00120
Flax
Pests (see list above)
(5X G)
001471-00059 001471-00125
(102 G)
001471-00143
(4 Ib/gal EC)
001471-00035
Grapes
Pests (see list above)
(52 G)
001471-00059
(10: G)
001471-00143
001471-00116
044215-00106
03470^-0^:4:
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
Issued: 4-17-64
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
1-036101-73
204
-------
/C20C2AA
/26C11AA
: /08020AA
/13011AA
EPA Index to Pesticide Chemicals
TRIFL'JRALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registration Number (continue:
•* u..
Grapes (continued) •'•„•'•-*'
(5 Ib/gal EC)
OC1471-00120
Grapefruit
Pests (see list above)
(10% G)
001471-00143
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Guar
Pests (see list above)
(0.2X G)
006735-00228
(0.252 G) .
006735-00236
001471-00116
034704-00242
002749-00219
044215-00073
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Hops
Pests (see list above)
(4 Ib/gal EC)
001386-00609 001471-<>OC35
034704-00242' 044215-00073
(5 Ib/gal EC)
001471-00120
Kale
Pests (see list above)
(0.2S G)
006735-00228
001471-00116
034704-00242
002749-00219
044215-OOC73
0:1471-00116
044215-00106
034704-00241
Issued: 4-17-84
1-036101-74
205
-------
/02C04AA
/28C12AA
/15CI2AA
EPA Index to Pesticide Chemicals
TRIFLL'RAUN
Appendix B
Listing by Site/Pest and Site/Formulation/Registratioc Nusber
Kale (continued)
(0.25% G)
006735-00236
001471-00035
034704-00241
(4 Ib/gal EC)
001366-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Lemon
Pests (see list above)
do: G)
001471-00143
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Mint (peppemint, spearmint)
Pests (see list above)
(4 Ib/gal EC)
001386-00609 001471-00035
034704-00242 044215-00073
(5 Ib/gal EC)
001471-00120 . ,
Mungbean
Pests (see list above)
(0.2Z G)
006735-00226
(0.25J G)
006735-00236
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
Issued: 4-17-84
OC1471-00035
034704-00241
001471-00116
034704-00242
001471-00116
034704-00242
001471-00116
044215-00106
001471-00116
034704-00242
1-036101-75
206
002749-OC219
044215-00073
002749-00219
044215-OOC75
034704-00241
002749-OC219
044215-00073
-------
EPA Index to Pesticide Che- . .-. _s
TRJFLURALIN
Appendix B
Listing by Site/Pest and Site/Formuiation/Registratior. Number (.continue:
Mungbean (continued)
(5 ib/gal EC)
001471-00120
/13C21BA Mustard (seed crop)
Pests (see list above)
(5% G)
001471-00125
(IDS G)
001471-00143
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116 C3470— CC-l-i
034704-00242 044215-00073 044215-00106
(5 Ib/gal EC)
001471-00120 .
/13C21AA Mustard
Pests (see list above)
(0.21 G)
006735-00228
(0.25S G)
006735-00236
(Si G)
001471-00125
(10S G)
001471-00143
(4 Ib/gal EC)
001386-00609 001471-00035 001471-00116 002749-00219
006735-00215 034704-00241 034704-O.C:-2 ' --:;: -OOC73
(5 Ib/gal EC)
...-". -v J 1 -
/05003AA Nectarlre
Pests (see list above)
(10* G)
OC1471-00143
Issued: 4-17-84 1-036101-76
207
-------
/15015AA
/14011AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
-isting by Site/Pest and Site/ronnulation/Registration Number (continued-)
Nectarine (continued)
001471-00035
044215-00073
(4 Ib/gal EC)
001386-00609
034704-00242
(5 Ib/gal EC)
001471-00120
Okra
Pests (see list above)
(0.2X G)
006735-00228
(0.25X G)
006735-00236
(0.93X G)
001598-00215
001471-00116
044215-00106
034704-00241
001159-00202
043640-00001
(1.47* G)
OOU961-00280
009198-00060
(1.751 G)
000961-00335
(51 G)
000226-00252
(10* G)
001471-00143
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Onion, Dry
Pests (see list above)
(4 Ib/gal EC)
001471-00035 001471-OC116
(5 Ib/gal EC)
001471-00120
002217-00480 007401-00349
001471-30059 009499-00004
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
Issued: 4-17-64
1-036101-77
208
-------
ZPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing bv Site/Pest and Site/Formiiatio:=£Nv- , ;&stration Number vcoritir.aec
*
Pests (see list above)
(:>'-, G)
'05004AA
/28016AA
/28074AA
OOli/1-00143
(4 Ib/gal EC)
OCi38b-30609
(5 Ib/gal EC)
001471-00120
Peach
Pests (see list above)
cio: G)
001471-00143
001471-00035 001471-00116
001471-00035
044215-00073
(4 Ib/gal EC)
001366-00609
034 70*, -00 24 2
(5 Ib/gal EC)
001471-00120
Peas
Pests (see list above)
(4 Ib/gal EC)
001366-00609 001471-00035
034704-00242 044215-00073
(5 Ib/gal EC)
001471-00120
Peas, Dry
Pests (see list above)
(4 Ib/gal EC)
001386-G06U9 001471^0035
034704-OC242 044215-00073
(5 ih/gs: ZC;
.001^71-00120
001471-00116
044215-00106
001471-00116
044215-00106
001471-00-116
044215-00106
034704-002^1
034704-001-1
03470^-00241
Issued: H-17-S4
1-036101-78
-------
/15008AA
/28015AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Lisv',-ig bv Site/Pest ar.-: Site/Fornul^Uor^V' *£'.£» t ion Nuc::.
r.'* ". ' " •-... -••*&&
vcor.tir.ue:
034704-00241
Peas. English
Pests (see list above)
(4 Ib/gal EC)
001386-00609 001471-00035
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Peas, Field
Pests (see list above)
(0.2* G)
006735-00228
(0.251 G)
006735-00236
(0.93S G)
001598-00215
001471-00116
034704-00242
002749-00219
044215-00073
001159-00202
043640-00001
(1.47% G)
000961-00260
009198-00060
(1.75S G)
000961-00335
(51 G)
000226-00252
(101 G)
001471-00143
(4 Ib/gal EC)
001471-00035
034704-00241
(5 Ib/gal EC)
001471-00120
Peanuts
Pests (see list above)
(10X WP)
001471-00136
(Spanish)
(0.2Z G)
006735-00228
002217-00480 007401-00349
001471-00059 009499-0000^
001471-00116
034704-00242
006735-00215
044215-00106
Issued: 4-17-84
1-036101-79
21
-------
/03008AA
/28017AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
'Appendix B
Listing by Site/Pest ar.d Site/Fonaul?tion/Reg:V" i.=.tion Number (cor
-"• . -y
Peanuts (continues)
(0.25°. G)
006735-00236
(55 G)
001471-00059
(10% G)
001471-00143
001*71-00035
03^04-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
(Florunner, Fieri giant}
(4 Ib/gal EC)
001471-00035
Pecan
Pests (see list above)
(10% G)
001471-00143
001471-00116
034704-00242
002749-00219
044215-00073
001472-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Peppers
Pests (see list above)
(0.2Z G)
006735-00228
(0.25S G)
006735-00236
CO.932 G)
001598-00215
001471-00116
034704-00242
002749-00219
044215-00073
Issued: 4-17-84
1-036101-80
211
-------
/05005AA
/14013AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
List'rig by Site/Pest and Site/Formula'ion/Registratior. Nunber (continue:
Peppers (continued)
001159-00202
043640-00001
(1.47% G)
000961-00280
009196-00060
(1.75% G)
000961-00335
(5% G)
000226-00252
(10% G)
001471-00143
(4 Ib/gal EC)
001386-00609
034704-00242
'(5 Ib/gal EC)
001471-00120
Plus
Pests (see list above)
(10% G)
001471-00143
002217-00480 007401-00349
001471-00059 009499-00004
001471-00035
044215-00073
001471-00116
044215-00106
001471-00035
044215-00073
(4 Ib/gal EC)
001366-00609
034704-00242
(5 Ib/gal EC)
001471-00120
Potato
Pests (see list above)
(4 Ib/gal EC)
001356-00609 OQ1471-OOC35
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
001471-00116
044215-00106
034704-00241
001471-00116
034704-00242
(Irish)
(1.47% G)
000961-00280
009198-00060
Issued: 4-17-84
034704-00241
034704-00241
002749-00219
044215-00073
001159-00202
043640-00001
002217-00480 007401-00349
1-036101-81
212
-------
/C50J6AA
/26051AA
/'28076AA
/28019AA
EPA Index to Pesticide Chemicals
.TRIFLURA1IN
Appendix B
Listing by Site/Pest and Site/Formulation/Kegistration Number (continue:
Prune
Fests (see list above)
(105 G)
001471-00143
001471-00035
044215-00073
(4 Ib/gal EC)
001386-00609
034704-00242
(5 Ib/gal EC)
001471-00120
Rape
Pests (see list above)
(51 G)
001471-00059 001471-00125
(102 G)
001471-00143
001471-00116
(4 Ib/gal EC)
001471-00035
(5 Ib/gal EC)
001471-00120
Safflower
Pests (see list above)
(5S G)
001471-00059 001471-00125
(10S G)
001471-00143
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106.
(5 Ib/gal EC)
001471-00120
Sorghum
Pests (see list above)
(4 Ib/gal EC)
001471-00035 001471-00116
(5 Ib/gal EC)
001471-00120
Issued: 4-17-64
001471-00116
044215-00106
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
1-036101-82
213
-------
/28023AA
I
/28020AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
Appendix B
Listing by Site/Pest and Site/Fcnnulation/Registratica Number (co:
•»,
Sorghue, Milo
Pests (see list above)
(4 Ib/gal EC)
001471-00035 001471-00116
(5 Ib/gal EC)
001471-00120
Soybeans
Pests (see list above)
(0.2% G)
006735-00228
(0.25% G)
006735-00236
(0.35% G)
006735-00233
(C.5% G)
006735-00234
(5% G)
001471-00059
(10% G)
001471-00143
(1.5 Ib/gal EC)
001471-00137
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Sugar Beets
Pests (see list
(5% G)
001471-00059
(10% G)
001471-00143
001471-00125
001471-00035
034704-00241
001471-00116
034704-00242
002749-00219
044215-00073
Issued: 4-17-84
1-036101-63
214
-------
/25C03AA
/28021AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
•v *~ •'
Listu&v by Site/Pe~t and. Site/Formulatior.^l-i.-^^raiior; Nur.:.-.:r (
Su££r Beets (continued)
•i • <•
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Sugarcane
Pests (see list above)
(plant cane)
(4 Ib/gal EC)
001386-00609 001471-00035
006735-00215 034704-00241
044215-00106
(5 Ib/gal EC)
001471-00120
(ratoon cane)
(4 Ib/gal EC)
001386-00609 001471-00035
006735-00215 034704-00241
044215-00106
(5 Ib/gal EC)
001471-00120
(plant cane and ratoon cane)
(4 Ib/gal EC)
001471-00116
034704-00242
001471-00116
034704-00242
001471-00116
034704-00242
001471-00035
034704-00241
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120 ...
Sunflower
Pests (see list above)
(5% G)
000226-00252 001471-00059
(10% G)
001471-00143
001471-00116
034704-00242
001471-00125
Issued: 4-17-84
1-036101-84
215
0027^-0:219
044215-OOCT5
OC2749-00219
044215-00073
002749-00219
044215-00073
00274-9-ec:: 9
044215-00073
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
.is- "eg by Site/Pest ar;' Site/F;
^ • v-'
Sunflower (continueo)
Nucb-'• (continue:
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
001471-00035
034704-00241
00:.471-0011b 002749-00219
0^704-00242 044215-00073
/02007AA
/C2008AA
/I1005AA
Tangeio
Pests (see list above)
G)
001471-00143
001471-00035
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Tangerine
Pests (see list above)
(10% G)
001471-00143
001471-OOC35
034704-00241
(4 Ib/gal EC)
001386-00609
006735-00215
044215-00106
(5 Ib/gal EC)
001471-00120
Tomato
Pests (see list abo:ve)
(direct seeded)
(0.93X G)
001598-00215
(1.472 G)
000961-00280
009198-00060
(5% G)
000226-00252
Issued: 4-17-84
001159-002C2
043640-00001
001471-00059
OC-: 471-00116
03^704-00242
00.471-00116
034704-00242
002749-00219
044215-00073
002749-00219
044215-00073
Gi,:;i7-00480 007401-00349
216
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnuiation/Regi^.-- '-.riot Nunsbtr (con:
locate (continued)
(10°. G;
001471-001 .,3 .
(3.1% WP)
. 001471-00:25
(4 Ib/gal EC/
001386-00609
006735-00115
044215-00:06
(5 Ib/gal EC;
001471 -0012C
(trar. spla^:
(0.2% G)
006735-00:2:
(0.25S G-
006735-00236
(0.93S G)
001598-00215
(1.471 G)
00096i-JC2b;-
009198-OOCfO
(1.75* G;
000961-00235
CSX G)
000226-00 2 51-
(102 G)
(4 It /gal L..
001386-rr«??
006733-.' .15
044215-00106
(5 Ib/gal SO
001471 -Ooliu
001471-00035
03-704-00241
001471-00116
034704-00242
002749-00219
044215-00073
001159-00202
043540-00001
002217-00480 007401-00349
OCis71-00059 009499-00004
001471-00035
02-7Oi-00241
001471-00116
034704-00242
002749-00219
044215-00073
Issued: 4-17-S4
1-036101-86
217
-------
.'13C26AA
/03009AA
/10008AA
/24007AA
EPA Index tc Pesticide Chemicals
TRIFLURALIN
Appendix B
Lsf'ng by Site/Pest and Site/Formulation/Registration Number (continued!
Turnip
Pests (see list above)
(0.21 G)
006735-00228
(0.25% G)
006735-00236
001471-00035
034704-00241
(4 lb/gal EC)
001386-00609
006735-00215
044215-00106
(5 lb/gal EC)
001471-00120
Walnut
Pests (see list above)
do: G)
001471-00143
001471-00116
034704-00242
002749-00219
044215-00073
001471-00035
044215-00073
(4 lb/gal EC)
001386-00609
034704-00242
(5 lb/gal EC)
001471-00120
Watermelon
Pests (see list above)
(5% G)
001471-00059 009499-00004
(10S G)
001471-00143
001471-00116
044215-00106
034704-00241
(4 lb/gal EC)
001386-00609
(5 lb/gal EC)
001471-00120
Wheat
Pests (see list above)
(winter)
(51 G)
001471-00125
001471-00035 001471-00116
Issued: 4-17-84
1-036101-87
218
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continu1--
Wheat (continued)
(lOi G)
001471-00143
(4 Ib/gal EC)
001386-00609 001471-OOG35 001471-00116 034704-00242
044215-00073 044215-00106
(5 Ib/gal EC)
001471-00120
(spring, duram)
(5S G)
001471-00059 0014-1-00125
(10°. G)
001471-00143
(4 Ib/gal EC)
001471-00035 001471-00116 034704-00242 044215-00073
044215-00106
(5 Ib/gal EC)
001471-00120
TERRESTRIAL NON-FOOD-CROP
(Ornamental Plants and Forest Trees)
/31010AA Achillea
Pests (see list above)
(0.931 G)
001598-00215
(1.47J G)
000961-00260 OwLiy?-: .. -2 002217-00480 007401-00349
009196-00060 043640-OpCCl
00j.471-00uob 009499-00004 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
(1.75X PrD)
004822-00123
Issued: 4-17-84 1-036101-88
-------
EPA Index to Pesticide Chemicals
TRIFLURAUN
Appendix B
Listing ':y Site/Pest and Site/Fcrmulation/Registration Number (continue;
/ 31501'.-j-. Adriatic Bellflover
' Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
/313C3AA African Trailing Daisy
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
r-
" /31423AA Agapanthus
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
/31013AA Ageratua
Pests (see list above)
(0.371 G)
000239-02262
(0.921 G)
000572-00226 000572-00260
(0.931 G)
001598-00215
(1.151 G)
000572-00200
,
000961-00280
009196-00060
(1.751 G)
000769-00377
(5% G)
000961-00405
001159-00202 002217-00480 007401-00349
043640-00001
000961-00335 006720-00066
001471-00066 009499-00004 042057-00o67
Issued: 4-17-64
1-036101-89
220
-------
/33C58AA
/35094AA
/31023AA
/31026AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Lis:->-g by Site/Pest ar.d Site/Formulatior^l-.^ijerratior. Number (.cor
Ageratuffi (continued) "'^
005481-00172 007001-00193
(4 Ib/gai EC)
001471-00065
(1.755 PrD)
004822-00123
Algerian Ivy (ground cover)
Pests (see list above)
(52 G)
001471-00066
«
(4 Ib/gal EC)
OOlwi-00065
Apple
Pests (see list above)
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
042057-00087
007001-00193
Arctotls
Pests (see list above)
(0.935 G;
001596-00215
(1.475 G)
000961-OC280 001159-00202
009198-00060 043640-00001
(55 G)
000961-00405 001471-00066
002217-00480 007401-00349
(4 Ib/gal EC)
001471-00065
(1.755 PrD)
004S22-OOI23
Aster
Pests (see list above)
(0.0955 G)
005887-00062
(0.375 G)
000239-02262
Issued: 4-17-84
009499-00004 042057-00087
005481-00172 007001-00193
1-036101-90
,221
-------
/35024AA
/34500AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Li?..^ng by Site/Past a-.i Site/Foroulj,:: • ,f-
Aster (continued)
n Number (continue;.
000572-00260
(0.922 G)
000572-00226
(0.932 G)
001598-00215
(1.152 G)
000572-00200
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(52 G)
000961-00405
(4 Ib/gal EC)
001471-^)0065
(1.752 PrD)
004822^00123
Austrian Pine
Pests (see list above)
(52 G)
000961-00405 001471-00066
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
005481-00172
Azalea Hybrids/Cultivars
Pests (see list above)
(0.0952 G)
005887-00062 ' -
(0.74S G)
000239-02263
(0.92X G)
000572-00260
000961-00283
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
042057-00067
007001-00193
Issued: 4-17-84
1-03610.1 -91
'222
-------
/25C25AA
/35C26AA
/34C25AA
/33086AA
/35030AA
/35031AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/RegiFtrstion Nuc:
-,» ' -1 ' V-
Balccypress
Pests (see list above)
(5% G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471-00065
Balsam Fir
OC'54£1-00172 007001-00193
Pests (see list above)
% G)
000961-00405 001471-00066
042057-00087
005481-00172 007001-00193
(4 Ib/gal EC)
001471-00065
Barberry
Pests (see list above)
(5% G)
000961-00405 001471-00066 042057-00087
007001-00193
(4 Ib/gal EC)
001471-00065 005481-00172
Big Blue Lilyturf (ground cover)
Pests (see list above)
(5% G)
00.1471-00066
(4 Ib/gal EC)
001471-00065
Black Locust
Pests (see list above)
(5* G)
000961-00405 001471-00066 042057-00087
007001-00193
(4 Ib/gal EC)
001471-00065 - 005461-00172
Black Walnut
Pests (see list above)
(5Z G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
Issued: 4-17-84
1-036101-92
223
-------
35032AA
/315C2AA
'. /35033AA
/34031AA
/31050AA
EPA Index to Pesticide Chemicals
TRIFLURA1IN
Appendix B
Listing by Site/Pest and Site/Formulatlon/Registration Number (cor.tinuec;
Blackgua
Pests (see list above/
(51 G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Blue Ceratostigma
Pests (see list above)
(5S G)
001471-00066
(4 Ib/gal EC)
001471-00065
Blue Spruce
Pests (see list above)
(5* G)
000961-00405 001471-00066
042057-00087
(4 Ib/gal EC)
001471-00065
Bozvood
Pests (see list above)
(5% G)
000961-00405 001471-00066
005481-00172 007001-00193
005481-00172
(4 Ib/gal EC)
001471-00065
Calendula
Pests (see list above)
(0.37S G)
000239-02262
042057-00087
007001-00193
(0.925; G)
000572-00226
(0.93% G)
001598-00215
(1.152 G)
000572-00200
U.47X G)
000961-00280
009198-00060
Issued: 4-17-84
000572-00260
001159-00202
043640-00001
002217-00460 007401-00349
I-036101-S3
224
-------
/31C51AA
/34035AA
EPA Index to Pesticide Chemicals
TRIFLURA1IN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (co:
Calendula (continued)
(1.75% G)
000769-00377
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
California Poppy
Pests (see list above)
(0.37% G)
000239-02262
OOC961 -00235 006720-00066
001471-00066
005481-00172
OOC:72-OC2bO
(0.92% G)
000572-00226
(0.93% G)
001596-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
. 009198-00060
(1.75% G)
000769-00377
(5% G)
000961-00*05
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
California Privet
Pests (see list above)
(5* G)
000961-00405 001471-00066
001159-00202
043640-00001
000961-00335
JOOcfc
009499-00004
007001-00193
042057-00087
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
Issued: 4-17-84
042057-00087
1-036101-94
225
-------
731057AA
.' /3536*AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registraticn Number (continued)
California Privet (continued)
(4 lb/gal EC)
001471-00065
Carnation
Pests (see list above)
(0.0952; G)
005887-00062
(0.37S G)
000239-02262
005481-00172 007001-00193
000572-00260
(0.922 G)
000572-00226
(0.93J G)
001598-00215
(1.15* G)
000572-00200
(1.471 G)
000961-00280- 001159-00202
009198-00060 043640-00001
(1.752 G)
000769-00377
(5% G)
000961-00405
(4 lb/gal EC)
001471-00065
(1.75: PrD)
Cl'4 522-00123
Co red na Cr.erry-Laurel
Pests (see list above)
000961-00335
001471-00066
005481-00172
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
Oo0961-00405 001471-00066 042057-00087
005481-00172 007001-00193
(4 lb/gal EC)
001471-00065
Issued: 4-17-84
1-036101-95
226
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Lis^&pg by Site/F^st ar..i Site/Fonnulatio^J^-SjStratior. Number (cor.tir.uec;
'•=;• /pi'
/ 31 '.• 5 9 AA Ceptaurea '' *
Fests (see list above)
(0.93°, G)
001596-00215
(1.47* G)
000961-00280 001159-00202 002217-004BO 007401-00349
009198-00060 043640-00001
(5% G)
000961-00405 001471-00066 00949i?-00004 042057-OOOS7
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
i (1.75% PrD)
004822-00123
/•J4.243AA Cherryberry Cotoneaster
Pests (see list above)
(55, G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471^)0065 005481-00172 007001-00193
/'35235AA Chinese Chestnut
Pests (see list above)
(51 G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471-00065 m 005481-00172 007001-00193
/35155AA Chinese Juniper
Pests (see list above)
(5: G)
000961-00405 001471^-00066 042057-00087
(4 Ib/gal EC) '
Gul471-jOU65 005481-00172 007001-00193
/31405AA Christoas Cheer
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Issued: 4-17-84
1-036101-96
227
-------
/ 31 Oc :>.-_-.
/31067AA
/34043AA
: /344C5AA
/31498AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest an-' Site/Fonnulat,ior. '.:•••• •' j'.'^.
& » • *- ••:•. ,:y
Chrysanthemum
Pests (see list above)
(0.095% G)
005887-00062
(0.93% G)
001598-00215
Numbe- ',ccr.tir.uec.
(1.471 G)
000961-00280
009198-00060
(5% G) .
000961-00405
'(4 Ib/gal EC)
001471-00065
(1.75S PrD)
004822-00^3
Cinquefoil
Pests (see list above)
(51 G)
000961-00405 001471-00066
001159-00202
043640-00001
001471-00066
0:5481-00172
005481-00172
(4 Ib/gal EC)
001471-00065
Common Camellia
Pests (see list above)
(52 G)
000961-00405 001471-00066
(4 lb/ga: EC)
001471-00065 005481-00172
Coaevr. l.ils-.-. (/_:;•;•
Pests isee ^.i'st above)
(5% G)
oo: rfi- • : • :••;:--.1-00066
(4 Ib/gal EC)
: 54":-00172
Conaon Tr. rift
Pests (see list above)
(51 G)
001471 -:0066
Issued: 4-17-84
002217-00480 007401-00349
009499-00004
007001-00193
042057-00087
007001-00193
042057-00087
007001-00193
042057-00067
007001-00193
1-036101-97
22 r
042057-00087
-------
31U/6AA
/31077AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
Appendix B
Lsting by Site/Pest and Site/Formulation/Reg:y.-:- ration Number (cor::
• • . v^1 -. '• '• "^
Coiaacr: Tnrift (continued)
(4 Ib/gal EC)
001471-00065
Coreopsis
Pests (.see list above)
(0.37% G)
000239-02262
(0.92: G)
000572-00226 000572-00260
(0.93i G)
001598-00215
(1.15S G)
000572-00200
(1.47- G)
000961-00280 001159-00202 002217-00480 0074G1-OC349
009198-00060 043640-00001
(1.75S G)
000769-00377 000961-00335 006720-00066
(5% G)
000961-00405 001471-00066 009499-00004 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
(1.75.S PrD)
004822-00123
Cosmos
Pests (see list above)
(0.372 G) .
000239-02262
(0.92* G)
000572-00226 000572-00260
(0.93X G)
001598-00215
(1.15Z G)
000572-00200
inuec
Issued: 4-17-84
1-036101-98
229
-------
/35133AA
/34244AA
/34563AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listi/.g by Site/Pest and Site/Fonnuiation/Registration Number (continue:
Cosmos (continued)
001;59-00202
0^3040-00001
000961-00335
OC1471-00066
005481-00172
(1.47; G)
000961-00280
009196-00060
(1.75% G)
000769-00377
(5* G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
Cotoneaster
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
Cottonvood
Pests (see list above)
(5% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Cranberry Cotoneaster
Pests (see list above)
(5% G)
000961-00405 . 001471-00066
(4 Ib/gal EC)
001471-00065
005*81-00172
Creeping Wireplant
Pests (see list above)
(5X G)
001471-00066
(4 Ib/gal EC)
001471-00065
Issued: 4-17-84
002217-00480 007401-00349
006720-00066
009499-00004 042057-OU087
007001-00193
042057-00087
007001-00193
042057-00067
007001-00193
1-036101-99
230
-------
/31063AA
/31084AA
/34050AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
by Site/Fes; asd Site/ Formulation/Registration Number (cor.:
Crown Vetch (Ornamental)
Fests (see list above)
5 G;
001471-00066
(5
(4 Ib/gal EC)
001471-00065
Daffodil
Pests (see list above)
(1.75% G)
000769-00377 OC0961-00335
Dahlias
Pests (see list above)
(0.37% G)
000239-02262
000572-U0260
(0.921 G)
000572-00226
(0.931 G)
001598-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
Deut;ia
Fefis (see list above)
(5% G)
000961-00405 001471-00066
001159-00202
043640^)0001
000961-00335
001471-00066
Or, : ' r •• r. r. -. - ^
oDHt^.—j vi / <.
006720-00066
002217-00480 007401-00349
006720-00066
009499-OOCOi 042057-00067
007001-001-93
Issued: 4-17-84
042057-00087
1-036101-100
231
-------
/31067AA
/31091AA
/35043AA
EPA Index to Pesticide Chemicals
TRJFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registration Number (continue:
Deutzia (continued)
(4 Ib/gal EC;
001471-0&065
Dianthus
Pests (see list above)
(0.932 G)
001598-00215
005481-00172 007001-00193
(1.472 G)
000961-00280
043640-00001
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
• 004822-00123
Dimorphotheca
Pests (see list above)
(0.932 G)
001598-00215
002217-OCK80 007401-00349 009198-00060
001471-00066
005481-00172
(1.472 G)
000961-00280
009198-00060
(52 G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Dogwood
Pests (see list above)
(0.742 G)
000239-02263
001159-00202
043640-00001
001471-00066
005481-00172
009499-00004
007001-00193
042057-00067
002217-00480 007401-00349
009499-00004
007001-00193
042057-00087
Issued: 4-17-84
1-036101-101
232
-------
/33130AA
7350i5AA
/33030AA
/34450AA
/3439iAA
EPA Index to Pesticide Checicals
IRIFLURALIN
Appendix B
•'••*. .. -C--V. , !J$.
List^tfg by Site/Pest ac:"' Site/Fomiu.l-atior.*.-'^';rC^ration Number (con'.inuec;
Douglas-Fir
Pests (see list above)
(58 G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172
Dwarf Coyotebrush (ground cover)
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
Eastern Hemlock
Pests (see list above)
(5% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065 005481-00172
English Ivy
Pests (see list above)
(58 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Erect Euonynus
Pests (see list above)
(52 G)
000961-00405 001471-00066
007001^)0193
042057-00087
007001-00193
005481-00172
(4 Ib/gal EC/
001471-00065
Euonymus Newport
Pests (see list above)
(5% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065 005481-00172
042057-00087
007001-00193
Issued: 4-17-64
042057-00087
007001-00193
1-036101-102
237
-------
/34058AA
/3505~AA
/311C1AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
i-sv-ug by Site/Pest ace Site/Formulaic* ;:- .^v^b^ion
European White Birch
Pests (see list above)
i G)
000961-004C5 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Firethorn
Pests (see list above)
(5% G)
000*61-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Flowering Dogwood
Pests (see list above)
% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Forget-Me-Not
Pests (see list above)
(0.372 G)
000239-02262
(0.92% G)
000572-00226
(0.93% G)
001598-00215
(1.152 G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(5% G)
000961-00405
Issued: 4-17-84
000572-00260
001159-00202
043640-00001
000961-00335
001471-00066
042057-00087
007001-00193
042057-00087
007001-00193
042057-00087
007001-00193
Nuafa- '«. c on t i r. u e c
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
1-036101-103
234
-------
/311C2AA
/31105AA
EPA Index to Pesticide Chemicals
TRJFLURAUK
Appendix B
.isting by Site/Pest and Site/Fommicrion/Re*;^ • vtion Nucbe~ \cont:
*'• '"" •: ''•"•
Forget-Me-Not (continued)
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
Four O'clock
Bests (see list above)
(0.372 G)
000239-02262
005481-00172 007001-00193
000572-00260
001159-00202
043640-00001
(0.92** G)
000572-00226
(0.93% G)
001598-00215
(1.15* G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
3
Gaillardia
Pests(see list above)
(0.37% G)
000239-02262
002217-00480 007401-00349
000961-00335 006720-00066
001471-00066
005481-00172
009499-00004 042057-00087
007001-00193
(0.92% G)
000572-00226
(0.93% G)
001598-00215
Issued: 4-17-84
OOJ572-00260
1-036101-104
235
-------
/31106AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registratior. Number
Gaillardia (continued)
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(5% G)
0009bl-00405
(4 Ib/gal EC)
001471-00065
(1.75* PrD)
004822-00123
Garden Balsam
Pests (see list above)
(0.375: G)
000239-02262
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
(0.92% G)
000572-OC226
(0.93% G)
001598-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(5% G)
000961-004C5
(4 Ib/gal EC)
001471-00065
Issued: 4-17-64
000572-00260
001159-00202
043640-^)0001
.001:961-00335
OC..471-00066
005481-00172
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
002217-00480 007401-00349
006720-00066
009499-0000*. 042057-00087
007001-00193
1-036101-105
236
-------
EPA Index to Pesticide Checicais
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number
Garden Balsa:: (continued)
(1.75% PrD)
004822-00123
/33128AA Gazania
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
/31993AA Gazania sangelo
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
/312 8 9AA Germander
Pests (see list above)
001471-00066
(4 Ib/gal EC)
001471-00065
/31111AA Gladiolus
Pests (see list above)
(0.17% G)
006993-00029 042057-00078
(0.174% G)
000239-02292
(0.37% G)
OOC239-C2262
(0.92% G)
000572-00226 000572-00260
(1.15% G)
OOC572-OG200
(1.47% G)
000961-00280
001159-00202 002217-00480 007401-00349
009198-00060 043640-00001
Issued: 4-17-84
1-036101-106
237
-------
/34181AA
/33139AA
/34246AA
/34304AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registratior. Number (cor.t:
Gladiolus (continued)
000961-00335
001471-00066
005481-00172
(1.75% G)
000769-00377
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Golden Bell
Pests (see list above)
(5* G)
000961-00405 001471-00066
005481-00172
(4 Ib/gal 'EC)
001471-00065
Goldmoss Sedum
Pests (see list above)
(5% G)
001471-00066 -
(4 Ib/gal EC)
001471-00065
Harlands Boxwood
Pests (see list above)
(5% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Hetzi Holly
Pests (see list above)
(5% G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
006720-00066
009499-00004
007001-00193
042057-00087
007001-00193
042057-00087
007001-00193
042057-00087
007001-00193
Issued: 4-17-84
1-036101-107
238
042057-00087
-------
/31121AA
/35070AA
/34G72AA
EPA Index to Pesticide Chemicals
TPJFLURALIN
Appendix B
..••
_is??sfg by Site/?e&t a..';i Si
Hiryu Azalea
Pests (see list above)
(51 G;
000961-00405 001471-00066
Number (cor.cir.uec
'*" ti^
042057-00087
(A Ib/gal EC)
001471-00065
Hollyhock
Pests (see list above)
(0.37% G)
000239-02262
005461-00172 007001-00193
000572-00260
001159-00202
043640-00001
(0.92S G)
000572-00226
(0.93S G)
001598-00215
(1.15* G)
000572-00200
(1.471 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(5% G)
009,499-00004
(1.75X PrD)
' 004822-00123
Honeylocust
Pests (see list above)
(5S G)
000961-00405 001i;i-00066
002217-00480 007401-00i4r
000961-00335 006720-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Honeysuocle
Pests (see list above)
(5% G)
000961-00405 001471-00066
042057-00087
007001-00193
042057-00087
Issued: 4-17-84
1-036101-108
239
-------
,•
/ JJ_
/33124AA
/34075AA
/34185AA
/35181AA
/34077AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
List^'t; by Site/Pe t ano. Site/Forauias. c; ;':. *f/i-.tion Numi
" ^ -- .;-e?
Honeysuckle (continued)
005481-00172 007001-00193
(4 lb/gal EC)
001471-00065
Hypericum coris
Pests (see list above)
(5S G)
001471-00066
(4 lb/gal EC)
001471-00065
Iceplant (ground cover)
Pests (see list above)
(5% G)
001471-00066
(4 lb/gal EC)
001471-00065 '
India Hawthorn
Pests (see list above)
(5% G)
000961-00405 001471-00066
005481-00172
(4 lb/gal EC)
001471-00065
»
Indica Azalea
Pests (see list above)
(5% G)
° 000961-00405 001471-00066
005481-00172
(4 lb/gal EC)
001471-00065
Intermediate Yew
Pests (see list above)
(5Z G)
000561-00-05 001471-00066
(4 lb/gal EC)
001471-00065
005481-00172
Ixora
Pests (see list above)
(0.93Z G)
001598-00215
Issued: 4-17-84
042057-00087
007001-00193
042057-00087
007001-00193
O4205'-00087
007001-00193
1-036101-109
240
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest ar..i 5ite/Formula_tion/Regf^ration Ninth •=••»• (cor.t:
'-• .s
Ixora (continued)
(1.47% G)
000961-0028C 001155-00202 002217-00480 007401-00349
009198-0006U 0*3640-00001
(5% G)
000961-00405 001471-00066 009499-00004 042057-00087
(4 Ib/gal EC)
001471-00065 005461-00172 007001-00193
(1.75% PrD)
004822-00123
/34078AA Japanese Andromeda
Pests (see list sb:vt)
(5S G)
000961-00405 001471-00066 042057-00067
(4 Ib/gal EC)
; 001471-00065 0054=1-00172 007001-00193
•
/34079AA Japanese Barberry
Pests (see list above)
(5% •:•)
000961-00405 011471-00066 042057-00087
(4 Ib/gal EC)
001471-00065 0054S1-00172 007001-00193
/35185AA Japanese Black Pine
Pests (see list above)
(5*'G)
000961-00405 00147.1-00066 042057-00067
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
/3524'tAA Japanese Dogvcud
Pests (see list above)
(5% G)
000961-00405 ;,...:-';-CC 066 042057-00087
(4 Ib/gal EC)
001471-00065 Gi.5ifc.-wi72 007001-00193
Issued: 4-17-84
1-036101-110
241
-------
/31135AA
/35076AA
/35192AA
EPA Index tc Pesticide Chemicals
TRIFLURALIN
Appendix B
List-ng by Site/Pest and Site/Fonnulaiion/Registration Number (continue:
Lirtieleaf Boxwood (continued)
(4 Ib/gal EC)
001471-00065
Lobelia
Pests (see list above)
(U.37% G)
000239-02262
OU5481-00172 007001-00193
000572-00260
(0.92% G)
000572-00226
(0.93% G)
001598-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
Loblolly Pine
Pests (see list above)
(5% G) .-
OOU961-00405 001471-00066
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
005481-00172
(4 Ib/gal EC)
001471-00065
London Plane '
Pests (see list above)
(5% G)
000961-00405 001471-00066
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
042057-00087
007001-00193
Issued: 4-17-84
042057-00087
1-036101-112
242
-------
/21135AA
/31137AA
£?A Index to Pesticide Chemicals
• TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registration Number (cont:
London Plane (continued)
(4 Ib/gal EC)
001471-00065
005481-00172 007001-00193
Lupines
Pests (see list above)
(0.93* G)
001598-00215
U.47X G)
000961-00280.
009198-00060
(5i G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.751 PrD)
004822-00123
Marigold
Pests (see list above)
(0.37: G)
000239-02262
001159-00202
043640-00001
001471-00066
005481-00172
(0.92: G)
000572-00226
(0.93X G)
001598-00215
(1.151 G)
000572-00200
(1.471 G)
000961-00280
009198-00060
(1.75S G)
000769-00377
(51 G)
000961-00405
(4 Ib/gal EC)
001471-00065
Issued: 4-17-84
000572-00260
001159-0320:
043640-00001
000961-00335
001471-00066
005481-00172
002217-00480 007401-00349
009499-00004
007001-00193
042057-00087
OC2217-00480 007401-00349
006720-00066
009499-00004
042057-00087
007001-00193
1-036101-113
243
-------
/33C38AA
/34094AA
/31140AA
EPA Index to Pesticide Chemicals
TEIFLURALIN
Appendix B
Listing by Site/Pest -and Site/Fonnulation/Registration Number (continue
Marigold (continued)
(1.75* PrD)
004822-00123
Mascarenegrass
Pests (see list above)
(5* G)
001471-00066
(4 Ib/gal EC)
001471-00065
Hock-Orange
Pests (see list above)
(5* G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Morning-Glory
Pests (see list above)
(0.37* G)
000239-02262
(0.92: G)
• 000572-00226
(0.93* G)
001598-00215
(1.15* G)
000572-00200
(1.47* :-^
ocor-:-::2eo
(1.75* G)
OOo 7oi»-00377
(5* 3)
OOC9&1-00405
(4 Ib/gal EC)
001471-00065
Issued: 4-17-64
000572-00260
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
1-036101-114
244
-------
/3-097AA
/35289AA
/35290AA
/31143AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
^ •*>1* • fl*
Lii^&ag by Site/? st a-d Site/Formulatioiv-yxj5stratioc Number (contir.uec
Moraing-Glory (continued)
(1.752 PrD)
004822-00123
Mountain-Laurel
Pests (see list above)
(52 G)
000961-00405 001471-00066
(4 lb/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Myoporua
Pests (see list above)
(52 G)
001471-00066
(4 lb/gal EC)
001471-00065
Myoporun laetum
Pests (see list above)
(52 G)
001471-00066
. (4 lb/gal EC)
001471-00065
Nasturtium
Pests (see list above)
(0.372 G)
000239-02262
(0.922 G)
000572-00226
(O.S32 G)
OC1598-00215
c.is: G <
000572-00200
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
Issued: 4-17-64
000572-00260
001159-00202
043640-00001
002217-00480 007401-00349
000961-00335 006720-00066
1-036101-115
245.
-------
/34541AA
/31266AA
/35C92AA
/35089AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
Appendix B
Lis'>-.g by Site/Pest ar.d %ite/Fcnnulf=;io:..;..' ^^.tion
Nasturtium (continuec;
Num:. .• (cotitisuec
001A71-00066
005481-00172
(5S G)
00 Z'9 61 -00^05
(4 Ib/gal EC)
001471-00065
(1.75S PrD)
004S22-00123
Needlepoint Ivy
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Nicotiana
Pests (see list above)
(0.932 G)
001598-00215
009499-00004 042057-00087
007001-00193
(1.471 G)
000961-00280
043640-00001
(5S G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75* PrD)
004822-00123
. Northern White-Cedar
Pests (see list above)
(51 G)
000961-00405 001471-00066
002217-00480 007401-00349 009196-00060
001471-00066
005481-00172
009499-00004
007001-00193
042057-00067
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Norway Maple
Pests (see list above)
(5% G)
000961-00405 001471-00066
Issued: 4-17-64
042057-00087
1-036101-116
246
-------
/3509CAA
/35G30AA
/3ld05AA
EPA Index to Pesticide Chemicals
' TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Reg:'^ ration Nurb^r (cc
-i" ' *
Norwav Made (continued)
(4 Ib/gal EC)
001471-00063
005481-00172 007001-00193
Norway Spruce
Pests (see list above)
(5Z G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065 0'J5481-00172
Ornamental and/or Shade Trees
Pests- (.see list above) ~~
(0.372 G)
000239-C2262
042057-00087
007001-00193
000572-00260
001159-00202
043640-00001
000572-00226
(0.932 G)
001598-00215
(1.152 G)
000572-00200
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(2.652 G)
000538-Ov. 10 2
(52 G)
001159-C"2C1
(1.752 PrD)
004822-'C 12 3
Ornamental Bulb. Plants
Pests (see list above)
(0.172.G)
006993-00029
Issued: 4-17-84
002217-00480 007401-00349
000961-00335 006720-00066
C09499-00004
1-036101-117
247
-------
/35006AA
/32005AA
/3IOC3AA
/33009AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
List.ug by Site/Pest and Site/Formulation/Registration Number (conti-uec.
Ornamental Deciduous Shrubs
Fests (see list above;
(0.68J G)
000538-00083
Ornamental Deciduous Trees
Pests (see list above)
(0.68* G)
000538-00083
Ornamental Evergreens
Pests (see list above)
(0.095* G)
005887-00062
(0.68* G)
000538-00083
000961-00283
000572-00260
(0.745 G)
OOC239-02263
(0.92* G)
000572-00226
(1.15* G)
000572-00200
Ornamental Flowering Plants
Pests (see list above)
(0.17* G)
006993-00029 ' 042057-00078
(0.174* G)
000239-02292
(1.15Z G)
002491-00291
(2.65* G)
000538-00102
(5* G)
001159-00201
Ornamental Ground Covers
Pests (see list above)
(0.68Z G)
000538-00083
Issued: 4-17-84
1-036101-118
248
-------
/33134AA
/34109AA
I£i. Index to Pesticide Chemicals
TRIFLURAL1N
Appendix B
Listing by Sice/Fes: i::: Site/Foraulation/Registration Number (continue:
Ornamental Woody Shrubs
Pests (see list above)
(Q.17% G)
006993-00029 042057-00078
(0.1745; G)
000239-02292
(0.37* G)
000239-02262
000572-00260
(0.92% G)
000572-00226
(0.93% G)
001598-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
(2.65% G)
000538-00102
(5% G)
001159-00201 009499-00004
(1.75% PrD)
004822-00123
Osteosperaun (ground cover)
Pests (see list above-)
(5% G) •
001471-00066
(4 Ib/gal EC)
001471-00065
Periwinkle
Pests (see list abcve^
(0.37% G)
000239-02262
002491-00291
001159-00202 002217-00480 007401-00349
043640-00001
000*61-00335 006720-00066
Issued: 4-17-84
1-036101-119
249
-------
/33094AA
/31154AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continue:
\
Periwinkle (continued)
000572-00260
(0.922 G)
GCl572-00226
(0.92: G)
001598-00215
(1.151 G)
000572-00200
(1.47: G)
000961-00280
0091*8-00060
(1.751 G)
000769-00377
(5Z G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75Z PrD)
004822-00123
Peruvian Verbena (ground cover)
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
Petunias
Pests (see list above)
(0.095* G)
005887-00062
(0.3-: G)
OO.C239-Q2262
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
(0.9:: G)
000572-00226
(0.93Z G)
001598-00215
Issued: 4-17-64
000572-00260
1-036101-120
250
-------
/'31156AA
/35255AA-
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
s.^sg bv Site/Pest and Site/ Formula tics??;' -?£stration .Number (coct
^ ' '• ^l:&
Pe:uaias (continued; " 4V
(1.155 G)
OOC572-OG200 :
(1.47S G)
000961-00280 001159-00202. 002217-00480 007401-003*9
009198^)0060 043640-00001
(1.75* G)
000769-00377 000961-00335 006720-00066
(55 G)
000961-00405 001471-00066 009499-00004 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
(1.75: PrD)
004822-00123
Phlox
Pests (see list above)
(0.93: G) t
001598-00215
(1.47S G)
000961-00280 001159-00202 002217-00480 007401-00349
009198-0006C 043640-00001
(5S G)
000961-00405 001471-00066 009499-00004 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
(1.75X PrD)
004822-00123
Pin Oak
Pests (see list above)
(51 G)
000961-00405 001471-00066 042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 OC7001-00193
ir.uec.
Issued: 4-17-64
1-0361 01-121
-------
/33137AA
/35102AA
/35204AA
/35105AA
/35106AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
j ...
by Site/Pest a~:". Site/ Formulaic: ;T-
Pineapple Guava
Pests (see list above)
(5i G)
000961-00405 001471-00066
.
ricc Nucber \cor.tir.ue.y
042057-0008
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
Point Reyes Ceanothus
Pests (see list above)
(5S G)
0014.71-00066
(4 Ib/gal EC)
001471-00065
Prunus
Pests (see list above)
(5: G)
000961-00405 001471-00066 042057-00067
(4 Ib/gal EC)
.001471-00065 005481-00172
Red Maple
Pests (see list above)
>i G)
000961-00405 001471-00066
007001-00193
(4 Ib/gal EC)
001471-00065
Red .Oak
042057-00087
005481-00172 007001-00193
Pests (see list above)
G)
000961-00405 001471-00066
(4 Ib/gal EC) -
001471-00065 005451-00172
Red Pine
Pests (see list above)
(5S G)
000961-00405 001471-00066
042057-00087
007001-00193
042057-00087
(4 Ib/gal EC)
001471-00065 005481-00172 007001-00193
Issued: 4-17-84
1-036101-122
252
-------
/35104AA
/34118AA
/313C2AA
/34120AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
-isting by Site/Pest and Site/Foroulatioa/Ree.i..1 ration Nucb
** * • ~
Redbuc
Pests (see list above)
(5% G)
000961-00405 001471-00066
°r (co
042057-00087
(4 Ib/gal EC)
001471-00065
Redcedar
Pests (see list above)
(51 G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065 005481-00172
Rhododendron Hybrids/Cultivars
Pests (see list above)
(0.095* G)
005887-00062
(0.74: G)
000239-02263
(0.92: G)
000572^)0260
Rock rose
Pests (see list above)
(5: G)
001471-00066
(4 Ib/gal EC)
001471-00065
Re be
Pests (see list above)
(0.095* G)
OC5887-00062
005481-00172 007001-00193
(0.171 G)
006993-00029
(C.174; C)
000239-02292
(0.37Z G)
000239-02262
Issued: 4-17-84
042057-00078
042057-00087
007001-00193
1-036101-123
253
-------
/31167AA
EPA Index to Pesticide Chemicals
TRIFLURAUN
Appendix B
Lisr.-'Lg by Site/Pest and Site/Fonnuia-tion/Registratioc Nuiber
Rose ', conti
002491-00291
002217-00480
001159-00201
(0.92: G)
000572-00226
(0.932 G)
00159b^)0215
(1.15: G)
000572-00200
(1.47: G)
001159-00202
(51 G)
000961-00405
042057-00087
(4 Ib/gal EC)
001471-00065
(1.751 PrD)
004822-00123
Rose Moss
Pests (see list above)
(0.9311 G)
001596-00215
(1.15: G)
000572-00200
001471-00066 009499-00004
005481-00172 007001-00193
(1.471 G)
000961-00280
009198-00060
(1.75* G)
000769-00377
(5: G)
000961-00405
(4 Ib/gal EC)
OC1471-00065
(1.75: PrD)
004822-00123
001159-00202
043640-00001
000961-00335
001471-0006b
005481-00172
002217-00480 007401-00349
00672C-GJ066
042057-00087
007001-OC193
Issued: 4-17-84
1-036101-1:4
254
-------
/3I169AA
/31503AA
/34208AA
/31171AA
EPA Index to Pesticide Chemicals
1RIFLURAUN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (conf
Rosemary (ground cover)
Pests (see list above)
(5i G)
001471-00066
(4 Ib/gal EC)
001471-00065
Rudbeckia
Pests (see list above)
(0.93: G)
001596-00215
001159-00202
043640-00001
001471-00066
Ou5481-00172
(1.47X G)
000961-00280
009198-00060
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Rupturewort
Pests (see list above)
(5S G)
001471-00066
(4 Ib/gal EC)
001471-00065
Sakaki
Pests (see list above)
(5% G)
000961-00^05. OD1471-000.66
002217-00480 007401-00349
009499-00004 042057-00087
007001-00193
005481-0017:
(4 Ib/gal EC)
001471-00065
Salvia
Pests (see list above)
(0.93Z G)
001598-00215
042057-00087
007001-00193
Issued: 4-17-84
1-036101-125
23 5
-------
EPA Index to Pesticide -."heticals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonnulation/Registration Number (co:
Salvia (continued)
(1.47% G)
000961-00260 001159-00202 002217-00460 Ot-:<.'Jl-OC349
009198-00060 043640-00001
r /34122AA
/34124AA
/3U73AA
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Sandankva Viburnum
Pests (see list above)
(52 G)
000^61-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Sasanqua Camellia
Pests (see list above)
(52 G)
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Scabiosa
Pests (see list above)
(0.932 G)
001598-00215
(1.471 G)
000961-00260
009198-00060
000961-00405
(4 IV/gal EC)
001471-00065
(1.75Z PrD)
004822-00123
001159--00202
043640-00001
001471-00066
005481-00172
009499-00004
007001-00193
042057-00067
007001-00193
042057-00087
007001-00193
042057-00087
002217-00480 007401-00349
009499-OOOC4
007001-00193
0*2057-00087
Issued: 4-17-84
1-036101-126
256
-------
/35113AA
/33125AA
/3214GAA
/31994AA
trA Ice ex to Pesticide Chemicals
TRIFLURAUN
Appendix B
Li^,r.g by Site/F/»st ar-d Site/Formuiati^Ov.i-^stration Number (
'•-' /y~*
Scarlet Oak.
vccctinuec.
Fests (see list abrve)
(52 G)
000961-00405 0014^1-00066
00;>
-------
/35209AA
/3420SAA
EPA Index to Pesticide Chemicals
TR1FLURALIN
Appendix B
-isr^g by Site/Pest ar,d £.1:te/FonEulef.do=jf ' f?£
Shasta Daisy ' '''-
Pests (see list above)
(0.37: G)
000239-02262
000572-00260
(0.92: G)
000572-00226
(0.931 G)
001598-00215
(1.15: G)
000572-00200
•(1.47: G)
000961-00280
009198-00060
(1.75: G)
000769-00377
(5S G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75: PrL)
004822-00123
Shore Juniper
Pests (see list above)
(5SI G)
000961-00405 001471-00066
001159-00202
043640-00001
000961-00335
001471-00066
005481-00172
005481-00172
(4 Ib/gal EC)
001471-00065
Shrub-Althea
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
002217-00480 007401-00349
006720-00066
009499-00004 042057-OGCS7
007001-00193
042057-00087
007001-00193
Issued: 4-17-84
1-036101-128
258
-------
/31268AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
.isting by Site/Pest and Site/Formula* ion/Regi :>•,•• \-_ti on Nuabe*- (cent;
-••
Silver Maple '"'
Pests (see list above)
(51 G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Snapdragon
Pests (see list above)
(0.371 G)
000239-02262
000572-00260
(0.921 G)
000572-OC226
(0.931 G)
001598-00215
(1.151 G)
000572-00200
(1.471 G)
OOU961-00280
009198-00060
(1.751 G)
000769-00377
(51 G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.751 PrD)
004822-00123
Snov~In-S'"""'er
Pests (see list abovt }
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065 .
001159-00202
043640-OOOOr
000961-00335
001471-00066
005481-00172
042057-00057
007001-00193
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
Issued: 4-17-84
I-C36.C1-129
259
-------
/31419AA
/33126AA
/3I188AA
EPA Index tc Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (conti^uec.
Saov-On-The-Mountain
Pests (see list above)
(0.93% G)
001598-00215
001159-00202
043640-00001
001471-00066
005481-00172
(1.47% G)
000961-0028&
009198-00060
(5% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75% PrD)
004822-00123
Sprenger Asparagus
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
St. John's-Wort (ground cover)
Pests (see list above)
(5% G)
001471-00066
(4 Ib/gal EC)
001471-00065
Stocks
Pests (see list above)
(0.93% G)
001598-00215
(1.15% G)
000572-00200
(1.47% G)
000961-00280
009198-00060
(1.75% G)
000769-00377
Issued: 4-17-84
001159-00202
0436^.0-00001
002217-00480" 007401-00349
009499-00004
007001-00193
042057-00087
002217-00480 . 007401-00349
000961-00335 006720-00066
1-036101-130
260
-------
/33106AA
/35117AA
/31194AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
isting by Site/Pest and Site/Formulation/Registration Number (continue:
Stocks (continued)
001471-00066
005481-00172
009499-00004
007001-00193
(5>% G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Strawberry (Ornamental) (ground cover)
Pests (see list above)
(52 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Sugar Maple
Pests (see list above)
(52 G)
000961-00405 001471-00066
042057-0008
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Sunflower
Pests (see list above)
(0.372 G)
000239-02262
(0.922 G)
000572-00226
(0.932 G)
001598-00215
(1.152 G)
000572-00200
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
Issued: 4-17-84
000572-00260
001159-00202
043640-00001
002217-00480 007401-00349
000961-00335 006720-00066
1-036101-131
261
-------
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/rest and Site/Fonnulation/r.egistraties Nucbe:
/670130A Firebreaks
Pests (see list above)
(4Z G) :
001471-00139
/67GG4uA Highway Rights-of-Way
Pests (see list above)
(41 G) :
001471-00139
/670090A Industrial Sites
Pests (see list above)
(42 G)
001471-00139
^
• /670110A Paved Surfaces
Pests (see list above)
(4S G)
001471-00139
(4 Ib/gal EC)
001471-00065
/670050A Railroad Rights-of-Way
Pests (see list above)
(4S G)
001471-00139
/670060A Utility Rlghts-of Way
Pests (see list above)
(4Z G)
001471-00139
.• _ - - _ » - u
/650130A
AQUATIC NON-FOOD
(Aquatic Sites)
Ditchbanks
Pests (see list above)
(4Z G)
001471-00139
Issued: 4-17-64
1-036101-138
262
-------
/ 3119 6 A/.
/31197AA
•EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B>v.
'•Vo ' ' V'-'.v r.<£
Listing by Site/Fest and Site/Formulation/.••-''^-•stration Number (con:
Sunflower (continued)
001471-00066
005481-00172
C5X G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Sweet Alyssum
Pests (see list above)
(0.372 G)
000239-02262
000572-00260
(0.922 G)
000572-00226
(0.932 G)
001598-00215
(1.152 G)
000572-00200
(1.471 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(52 G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Sweet Pea
Pests (see list above)
(0.372 G)
000239-02262
001159-00202
043640-00001
000961-00335
001471-00066
OQ5461-00172
009499-00004 042057-00067
007001-00193
002217-00480 007401-00349
006720-00066
009499-00004 042057-00087
007001-00193
(0.922 G)
000572-00226
000572-00260
Issued: 4-17-84
1-036101-132
263
-------
/34153AA
/31198AA
EPA Index to Pesticide
TRIFLURALIN
Appendix B
». •
Lis_.-tig by Site/P-st a:xj. £i
* • -* '
Sweet Pea (continued)
(0.931 G)
001598-00215
(1.151 G)
000572-00200
(1.472 G)
000961-00280
009198-00060
(1.752 G)
000769-00377
(51 G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Sweet Viburnum
Pests (see list above)
(52 G)
000961-00405 001471-00066
001159-00202
043640-00001
OOC961-00335
001471-00066
005481-00172
005481-00172
(4 Ib/gal EC)
001471-00065
Sweet William
Pests (see list above)
(0.932 G)
t*:J. :n Nu-ber (costi" _-.
002217-00480 007401-003*9
•
006720-00066
009499-OOOC4
007001-00193
042057-00087
007001-00193
(1.472 G)
OQC^tl-00280
009198-00060
(52. G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.752 PrD)
004822-00123
Issued: 4-17-84
GC.159-OG202 002217-00-6;
043640-00001
001471-00066 009499-00004 042057-00087
005481-00172 007001-00193
1-036101-133
264
-------
/35118AA
/35119AA
/34218AA
/31455AA
/31025AA
/35120AA
/34223AA
EPA Index to Pesticide Chemicals
TRJFLURALIN
Appendix B
Listing by Site/Pest and Site/Fonsul ,.. .ion/Reg;-'
Sweetgum
Pests (see list above)
.(51 G)
000961-QG4G5 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Sycamore
Pests (see list above)
(51 G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Thorny Elaeagnus
Pests (see list above)
(52 G)
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Treasure Flower
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Tulips
Pests (see list above)
(1.751 G)
000769-00377 000961-00335
Tuliptree
Pests (see list above)
G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
Vanhoutte Spirea
Pests (see list above)
(51 G)
000961-00405 001471-00066
042057-00087
007001-00193
042057-00087
007001-00193
042057-00087
007001-00193
Ovr~:0-00066
042057-00087
007001-00193
Issued: 4-17-64
042057-00087
1-036101-134
265
z Numb* • (continued:
-------
/3I206AA
/31207AA
/34258AA
/34224AA
/35227AA
/35126AA
EPA Index to Pesticide Chemicals
TRIFLURALJN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Niaaber (.continuec;
Vanhoutte Splrea (continued)
(4 Ib/gal EC)
001471-00065
Verbena
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Veronica
Pests (see list above)
(51 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Viburnum Doublefile
Pests (see list above)
(52 G)
000961-00405 001471-00066
005481-00172 007001-00193
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Weigela Bristol Ruby
Pests (see list above)
(51 G)
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
White.Ash
Pests (see list above)
(52 G)
000961-00405 001471-00066
042057-00087
007001-00193
042C57-00087
(4 It/gal EC)
001471-OOOeS
White Pine
Pests (see list above)
(52 G)
OOC961-00405 001471-00066
005481-00172 007001-00193
042057-00087
Issued: 4-17-84
1-036101-135
266
-------
/35127AA
/35128AA
/34232AA
/31499AA
/340/4AA
/35253AA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
List;' ig by Site/Pest and Site/Formulation/Registration Number (continued)
White Pine (continued)
(4 Ib/gal EC)
001471-00065
005481-00172 007001-00193
White Spruce
Pests (see list above)
(52 G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Willov
Pests (see list above)
(5S G)
000961-00405 001471-00066
(4 Ib/gal EC)
001471-00065
005481-00172
042057-00087
007001-00193
Winged Euonymus
Pests (see list above)
(5% G)
000961-00405 001471-00066
005481-00172
(4 Ib/gal EC)
001471-00065
Woolly Yarrov
Pests (see list above)
(52 G)
001471-00066
(4 Ib/gal EC)
001471-00065
Wright Viburnum
Pests (see list above)
(52 G)
000961-00405 001471-00066
042057-00087
007001-00193
(4 Ib/gal EC)
001471-00065
005481-00172 0070C1-00193
Yev Podocarpus
Pests (see list above)
(5Z G)
000961-00405 001471-00066
Issued: 4-17-84
042057-00087
1-036101-136
267
-------
/3I213AA
/670010A
/67015QA
EPA Index to Pesticide Chemicals
TRIFLURALIN
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continue:
Yev Podocarpus (continued)
(4 Ib/gal EC)
001471-00065
Zinnia
Pests (see list above)
(0.095* G)
005887-00062
(0.37Z G)
000239-02262
005481-00172 007001-00193
000572-00260
001159-00202
043640-00001
002217-00480 007401-00349
(0.922 G)
000572-00226
(0.93X G)
001598-00215
(1.151 G)
000572-00200
(1.47X G)
000961-00280
009198-00060
(1.75: G)
000769-00377
(5t G)
000961-00405
(4 Ib/gal EC)
001471-00065
(1.75Z PrD)
004822-00123.
(Noncrop, Wide Area. Aad General Outdoor Treatments)
Airport Runways
Pests (see list above)
(4X G)
001471-00139
Fencerovs (Non-agricultural)
Pests (see list above)
(4* G)
001471-00139
000961-00335 006720-00066
001471-00066 009499-00004 042057-00087
005481-00172 007001-00193
Issued: 4-17-64
1-036101-137
268
-------
APPENDIX IV
BIBLIOGRAPHY APPENDICES
269
-------
BIBGUIDE-1
GUIDE TO USE OF THIS BIBLIOGRAPHY
1. CONTENT OF BIBLIOGRAPHY. This bibliography contains
citations of all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources for studies in this
bibliography have been the body of data submitted to EPA
and its predecessor agencies in support of past regulatory
decisions. Selections from other sources including the
published literature, in those instances where they have
been considered, will be included.*
2. UNITS OF ENTRY. The unit of entry in this bibliography
is called a "study." In the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
"studies" generally have a distinct title (or at least a
single subject), can stand alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study.
3. IDENTIFICATION OF ENTRIES. The entries in this bibliography
are sorted numerically by "Master Record Identifier," or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It is not related to the six-digit "Accession Number"
which has been used to identify volumes of submitted
studies; see paragraph 4(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late in the review may be preceded by a nine-character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number is
"also to be used whenever specific reference is needed.
A. FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards of the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
*A largely complete set of toxicity studies were submitted to the Agency,
at a time that was too late for full reviews to have been completed
and subsequently included in the Standard. A partial list of
these data are included in an addendum to this Bibliography.
They may be cited to support registration of products containing
trifluralin, subject to possible questions about their validity.
270
-------
BIBGUIDE-2
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four-digit date is followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??), the Agency was unable to determine
or estimate the date of the document.
c. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets-.
d. Trailing Parentheses. For studies submitted to the
Agency in the past, the trailing parentheses include
(in addition to any self-explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
"received."
(2) Administrative Number. The next element,
immediately following the word "under," is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission.
(3) Submitter. The third element is the submitter,
following the phrase "submitted by." When
authorship is defaulted to the submitter, this
element is omitted.
(4) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA accession number of the volume
in which the original submission of the study
appears. The six-digit accession number follows
the symbol "CDL," standing for "Company Data
Library." This accession number is in turn
followed by an alphabetic suffix which shows the
relative position of the study within the volume.
For example, within accession number 123456, the
first study would be 123456-A; the second, 123456-
B; the 26th, 123456-Z; and the 27th, 123456-AA.
271
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00022257 Eli Lilly and Company (1967) Supplemental Residue Data: Triflura-
lin—Irish Potatoes. (Unpublished study received Mar 12, 1968
under 1471-35; submitted by Blanco Products Co., Div. of Eli
Lilly and Co., Indianapolis Ind.; CDL:006227-B)
00022376 Shaw, A.; Thaemert, E.; Binning, L.K.; et al. (1975) Eptam 7-E +
Treflan 4-E Tank Mix on Beans. (Unpublished study received Jul
20, 1976 under 476-2154? prepared in cooperation with Morse Lab-
oratories, Inc. and Univ. of Wisconsin, submitted by Stauffer
Chemical Co., Richmond, Calif.; CDL:224906-A)
00022793 Sckerl, M. (1978) [Residue Data Treflan and Planavin Herbicides in
Soybeans]: TIR-24-305-76-C. (Unpublished study including TIR-
24-143-72-B, received Jul 18 1979 under 201-279; prepared in
cooperation with Agri-Research, submitted by Shell Chemical Co.,
Washington, D.C.; CDL:098395-O)
00023105 Fisher, D.E.; St. John, L.E., Jr.; Guntenman, W.E.; et al. (1965)
Fate of Banvel T, loxynil, Tordon and Trif luralin in the dairy
cow. Journal of Dairy Science 48(12):1711-1715. (Also in un-
published submission received Apr 8, 1976 under 876-203; submit-
ted by Velsicol Chemical Corp., Chicago, 111.; CDL:235226-Y)
00024248 Eli Lilly and Company (1964) Determination of Trifluralin Residues
in Agronomic Crops When the Pesticide BHC, Ethion and/or Zineb
Are Present in the Crop Sample. Method 5801110 dated Oct 15,
1964. (Unpublished study received Feb 16, 1966 under 1471-55;
submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, Ind.; CDL: 092800-^)
00024731 Penner, D. (1971) Effect of temperature on phytotoxicity and root
uptake of several herbicides. Weed Science 19(5):571-575. (Al-
so in unpublished submission received Jul 19, 1978 under 201-
403; submitted by Shell Chemical Co., Washington, D.C.; CDL:
234470-AI)
00026049 Merkle, M.G.; Spears, B.R. (1969) Crop Residue Report: [Vernam 6E
Treflan 4E]: FSDS No. B-0458. (Unpublished study including
FSDS nos. B-0457, B-0456, B-0455..., received Dec 8, 1969 under
476-1807; prepared in cooperation with Texas A & M Univ., sub-
mitted by Stauffer Chemical Co., Richmond, Calif.; CDL:003788-B)
272
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00026054 Golab, T.; Herberg, R.J.; Parka, S.J.; et al. (1967) Metabolism of
Carbon-14 Trifluralin in carrots. Journal of Agricultural and
: Food Chemistry 15 (4): 638-641. (Also in unpublished submission
received Jan 3, 1971 under OF0981; submitted by Shell Chemical
Co., Washington, D.C.; CDL:091687-C)
00028772 Atkins, E.L.; Greywood, E.A.; Macdonald, R.L. (1973) Toxicity of
: Pesticides and Other Agricultural Chemicals to Honey Bees: Labo-
ratory Studies. Rev. By Univ. of California—Riverside, Dept.
of Entomology. Riverside, Calif.: UC, Agricultural Extension
Service. (Also in unpublished submission received Apr 2, 1980
under 464-556; submitted by Dow Chemical U.S.A., Midland, Mich.;
CDL:242149-Z)
00030932 Baychem Corporation (1973) Treflan plus Sencor—Soybeans. (Unpub-
lished study received Feb 15, 1973 under 1471-EX-40; submitted
by Blanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
Ind.; CDL:210010-B)
00032811 Blanco Products Company (1978) Trifluralin—Corn. (Unpublished
.study received Jun 23, 1980 under CO 80/9; CDL:242716-B)
00033086 Manning, P.B.; Kerr, T.W.; Olney, C.E.; et al. (1964) [Residue
Study]. (Unpublished study including published data, received
Jan 14, 1965 under 100-471; prepared by Univ. of Rhode Island,
Agricultural Experiment Station and others, submitted by Ciba-
Geigy Corp., Greensboro, N.C.; CDL:000459-E)
00033087 Manning, P.B.; Kerr, T.W.; Olney, C.E.; et al. (1964) [Residue
Study]. (Unpublished study including published data, received
Jan 14, 1965 under 100-471; prepared in cooperation with Univ.
of Rhode Island, Agricultural Experiment Station and Gaspro,
Ltd., submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:
000459-F)
00036607 Emmerson, J.L.; Arthur, B.H.; Ansley, A.D.; et al. (1979) Acute
Hazard Evaluation of Treflan™(R)t 4EC, Lot X-27572 Including
Oral, Dermal, Ocular and Inhalation Studies. (Unpublished study
received Jul 10, 1980 under 1471-116; submitted by Blanco Prod-
ucts Co., Div. of Eli Lilly and Co., Indianapolis, Ind.; CDL:
242796-A)
273
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00044337 Emmerson, J.L.; Pierce, E.G.; McGrath, J.P.; et al. (1980) The
Chronic Toxicity of Compound 36352 (Trifluralin) Given as a
Component of the Diet to Fischer 344 Rats for Two Years: Studies
R-87 and R-97. (Unpublished study received Sep 18, 1980 under
1471-35; submitted by Elanco Products Co. , Div. of Eli Lilly
and Co. , Indianapolis, Ind. ; CDL:243289-A, 243290)
00044338 Emmerson, J.L.; Owen, N.V.; McGrath, J.D.; et al. (1980) The Chron-
ic Toxicity of Compound 36352 (Trifluralin) Given as a Compo-
nent of the Diet to the B6C3F1 Mouse for 24 Months: Studies M-
9067 and M-9077. (Unpublished study received Sep 18, 1980 under
1471-35; submitted by Elanco Products Co. , Div. of Eli Lilly
and Co., Indianapolis, Ind.; CDL: 243291-A; 243292; 243293)
00047591 Elanco Products Company (1967?) Determination of Trifluralin, Di-
phenamid and N-Methyl-2,2-diphenylacetamide in Tomatoes. Undat-
ed method no. 5800600. (Unpublished study received Aug 22, 1968
under 8F0717; CDL:093027-B)
00047639 Armock, I.; Knight, C.W. ; Leavitt, R.A.; et al. (1979) Summary:
[Efficacy of Trifluralin for Weed Control in Rape]. (Unpub-
lished study including PR no. 1124, received Jul 29, 1980 under
OE2394; prepared in cooperation with Michigan State Univ. ,
Pesticide Research Center and others, submitted by Inter-
regional Research Project No. 4, New Brunswick, N.J.; CDL:
099525-A)
00057545 Stauffer Chemical Company (1981) Eptam 7-E + Treflan 4-EC Tank Mix
Applied Preplant Incorporated to Sunflowers. (Compilation;
unpublished study received Feb 13, 1981 under 476-2154; CDL:
244420-A)
00057546 Stauffer Chemical Company (1981) Eptam 7-E + Treflan 4-EC Tank Mix
Applied Postemergence Incorporated in Sugarbeets. (Compilation;
unpublished study received Feb 13, 1981 under 476-2154; CDL:
244420-B)
00057547 Stauffer Chemical Conpany (1979) Eptam 7-^1 + Treflan 4^C Tank Mix
Applied Preplant Incorporated to Snap Beans. (Compilation;
unpublished study received Feb 13, 1981 under 476-2154; CDL:
244420-C)
00059531 Eli Lilly and Company (1975) Peanuts-Treflan plus Vernolate.
(Compilation; unpublished study received Mar 13, 1975 under
1471-EX-47; CDL:224660-B)
274
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00059532 Johnson, W.S. (1972) Determination of Trifluralin in Agricultural
Crops and Soil. Method No. 5801616 dated Jul 20, 1972. (Unpub-
lished study received Mar 13, 1975 under 1471-EX-47; submitted
by Elanco Products Co., Div. of Eli Lilly & Co., Indianapolis,
Ind.; CDL:224660-C)
00062921 Emmerson, J.L.; <3omez, S.R.; Dorato, M.A.; et al. (1980) The Acute
Inhalation Toxicity of Treflan M.T.F., a Formulation of Tri-
fluralin, in the Fischer 344 Rat: Study R^J-95-80. (Unpublished
study received Dec 11, 1980 under 1471-116; submitted by Elanco
Products Co., Div. of Eli Lilly and Co., Indianapolis, Ind.;
CDL:243937-A)
00067222 Frank, R.; Johnson, W.S.; Sieck, R.F.; et al. (1978) Residue Data
on Trifluralin and Vernolate in Peanuts When Preplant Incorpo-
rated as an EC Formulation. Includes procedure no. 5801616
dated May 24, 1977 and undated procedure no. 5801690. (Unpub-
lished study received Jul 25, 1980 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
Ind.; CDL:243059-A.)
00067371 Danhaus, R.G.; Mestdagh, P.; Schreurs, R.; et al. (1980) Residues
of Triallate, Trifluralin and EPTC in Oilseeds following Pree-
mergent Applications of Far-go (R), Far-go (R)t + Treflan (R),
and Far-go (R) + Eptam (R) Tank Mixes: Report No. MSL-1323.
Final rept. Includes undated methods entitled: Analytical resi-
due method for triallate and trifluralin in oilseed crops and
Analytical residue method for EPTC in flax seed. (Unpublished
study, including published data, received Dec 23, 1980 under
524-145; submitted by Monsanto Co., Washington, D.C.; CDL:
099852-A)
00067430 Harrison, S.L.; Nygren, R.E.; Boros, E.J.; et al. (1980) Chloramben
and Trifluralin Analyses of Sunflowers Treated with Amiben (R)
+ Treflan Tank Mix PPI: Project No. 10123/279D. (Unpublished
study received Dec 19, 1980 under 264-138; prepared in coopera-
tion with Biospherics, Inc. and Allied Chemical Services, Ltd.,
Canada, submitted by Union Carbide Agricultural Products Co.,
Inc., Ambler, Pa.; CDL:243984-B)
275
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00067433 Harrison, S.L.; Boros, E.J. (1980) Chloramben, Trifluralin & Metri-
buzin (+ DADK) Analyses of Soybeans Treated with Amiben + Tref-
lan + Senoor or Lexone Tank Mix PPI: Project Report 10123/1280A.
(Unpublished study received Dec 19, 1980 under 264-138; prepared
in cooperation with Southern Illinois Univ., Plant & Soil Sci-
ence Dept. and others, submitted by Union Carbide Agricultural
Products Co., Inc., Ambler, Pa.; CDL:243984-F)
00067435 Decker, O.D.; Griggs, R.D. (1980) Determination of Trifluralin in
Agricultural Crops and Soil. Undated method AM-AA-CA-R023-AA-
755. (Unpublished study received Dec 19, 1980 under 264-138;
prepared by Eli Lilly and Co., submitted by Union Carbide Agri-
cultural Products Co., Inc., Ambler, Pa.; CDL:243984-1)
00070736 Frank, R.; Sieck, R.F.; Shuey, E.W. (1978) Trifluralin and Trial-
late on Barley and Wheat: Residue Data. (Unpublished study re-
ceived Feb 20, 1981 under 1471-35; submitted by Elanco Products
Co., Div. of Eli Lilly and Co., Indianapolis, Ind.; CDL:
244413-A)
00080320 Fisher, D.E.; St. John, L.E., Jr.; Gutenmann, W.H.; et al. (1965?)
Fate of Banvel T, loxynil, Tordon, and Trifluralin in the-Dairy
Cow. (Unpublished study received Feb 7, 1967 under unknown ad-
min, no.; prepared by Cornell Univ., Depts. of Engineering
Physics, Entomology and Animal Husbandry, submitted by Elanco
Products Co., Div. of Eli Lilly and Co., Indianapolis, Ind.;
CDL:105544-D)
00080322 Nellor, J.E. (197?) Influence of Orally Administered Trifluralin
on the Performance and Well Being of Lactating Goats. (Unpub-
lished study received Feb 7, 1967 under unknown admin, no.;
prepared by Michigan State Univ., Dept. of Animal Husbandry,
submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, Ind.; CDL:105544-F)
00083645 Harris, P.N. (1966) Dog Studies. (Unpublished study received Nov
13, 1966 under 7F0555; submitted by Elanco Products Co., Div. of
Eli Lilly and Co., Indianapolis, Ind.; CDL:090691-A)
276
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00083650 Ermerson, J.L.; Harris, P.N. (1964) Subacute Studies. (Unpublished
study received Nov 13, 1966 under 7F0555; submitted by Elanco
Products Co., Div. of Eli Lilly and Co., Indianapolis, Ind.;
CDL:090691-G) ;
00084581 Decker, O.D.; Sieck, R.F.; Shuey, E.W. (1981) Trifluralin in Flax-
seed When Used as Pre-plant Soil Incorporated Application for
Weed Control: Residue Data. (Unpublished study received Sep 24,
1981 under 1471-35; prepared in cooperation with North Dakota
State Univ., submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, Ind.; CDL:070366-A)
00085087 Emmerson, J.L.; Ansley, A.D.; Quarles, J.A.P.; et al. (1981) The
Acute Inhalation ToxLcity Testing of Treflan 5EC, an Emulsifi-
able Concentrate Formulation (AT-5071) Containing Trifluralin
(36352), in the Fischer 344 Rat: Study No. R-H-56-81. (Unpub-
lished study received Sep 24, 1981 under 1471-120; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
Ind.; CDL:246039-E)
00093190 Shell Chemical Company (1974) 1973—Residue Data for Treflan in
Cottonseed from Stoneville, Mississippi: TTR-24-195-73 (Part
II). (Unpublished study received Feb 28, 1975 under 5F1599;
CDL:094364-O)
00093549 Manning, P.B.; Kerr, T.W.; Olney, C.E.; et al. (1964) Residue
analysis of various fruits and vegetables treated with DCPA,
prometryne and trifluralin for weed control. Pages 105-108, In
Proceedings of the Northeastern Weed Control Conference: Volume
18; Jan 8,9,10, 1964, New York, N.Y. N.P. (Also in unpub-
lished submission received Dec 1, 1964 under 7F0559; submitted
by Geigy Chemical Co., Ardsley, N.Y.; CDL:090702-E)
00093553 Elanco Products Company (1966?) Radioactive Metabolic Studies.
(Unpublished study received Jan 4, 1967 under 7F0555; CDL:
090690-B)
00093554 Elanco Products Company (1966) Summary of Residue Data. (Com-
pilation; unpublished study received Jan 4, 1967 under 7F0555;
CDL:090690-C; 090689)
277
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trif luralin Standard
MRID CITATION
00093555 Blanco Products Company (1966) Trif luralin—Cantaloupe and Cucum-
ber. Includes procedure no. 5801000 dated Jul 1, 1964; pro-
cedure no. 5801110 dated Oct 15, 1964; procedure 5801210 dated
Jan 1966. (Compilation; unpublished study received Jan 4, 1967
under 7F0555; CDL:090689-A)
00093574 Elanco Products Company (1966) [Residue of Trifluralin—Irish
Potatoes]. (Compilation; unpublished study received Jan 24,
1967 under 7F0586; CDL:090752-A)
00093634 Van Duyn, R.
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trif luralin Standard
MRID CITATION
00105646 Blanco Products Co. (1965) [Trifluralin Residue Data—Peanuts].
(Conpilation; unpublished study received Mar 23, 1965 under
1471-35; CDL:005968-B)
.00105648 Blanco Products Co. (1966) Trif luralin—Sugar Beets. (Unpublished
study received Mar 31, 1967 under 1471-35; CDL:006208-B)
00105650 Little, C.; Hunt, H. (1968) Supplemental Trifluralin Residue Data
on Cole Crops Harvested in 1967 and 1968. (Unpublished study
received Feb 10, 1969 under 1471-35; submitted by Blanco Prod-
ucts Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:
006241-B)
00105655 Mobay Chemical Corp. (1973) Residue Data on Treflan: Preplant Soil
Incorporated Followed by Sencor Surface Applied for Preemergence
Weed Control in Soybeans. (Compilation; unpublished study re-
ceived Mar 1, 1973 under 3125-277; CDL:007214-B)
00105666 Blanco Products Co. (1966) The Results of Tests on the Amount of
Residue Remaining, Including a Description of the Analytical
Method Used: [Trifluralin]. (Compilation; unpublished study re-
ceived on unknown date under 6F0493; CDL:090567-A)
00105667 Blanco Products Co. (1966) Residue Data on Trifluralin in Citrus,
Stone Fruit,- Nuts, Vine Crops, and Pome Fruit. (Compilation;
unpublished study received on unknown date under 7G0533; CDL:
090649-A)
00105668 Eli Lilly and Co. (1967) Residue Data on Trifluralin in Sugarcane.
(Unpublished study received on unknown date under 7G0595; CDL:
090765-A)
00105669 Blanco Products Co. (1967) The Results of Tests on the Amount of
Residue Remaining, Including a Description of the Analytical
Method Used: [Trifluralin]. (Compilation; unpublished study
received Nov 28, 1967 under 8F0664; CDL:091163-A)
00105670 Eli Lilly and Co. (1967) Residue Data on Trifluralin in Watermelon,
Celery, Mungbeans, and Guar Beans. (Unpublished study received
Feb 14, 1968 under 8F0664; submitted by Blanco Products Co.,
Div. of Eli Lilly and Co., Indianapolis, IN; GDL:091164-A)
00105673 Eli Lilly and Co. (1967) Residue Data on Trifluralin in Sunflower
Seed. (Compilation; unpublished study received Apr 5, 1968
under 8F0679; CDL:091186-A)
279
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00105674 Eli Lilly and Co. (1968) Supplemental Residue Data on Trifluralin
in Sugarcane. (Compilation; unpublished study received Apr 6,
1968 under 8F0715; CDL:091238-A)
00105675 Elanco Products Co. (1968) [Trifluralin: Residues in Almonds and
Other Nuts]. (Conpilation; unpublished study received Dec 1,
1968 under 8F0721; CDL:091243-A)
00105677 Elanco Products Co. (1968) [Trifluralin: Residues in Apricots and
Other Crops]. (Compilation? unpublished study received May 6,
1968 under 8F0731; CDL:091260-A; 091261)
00105678 Elanco Products Co. (1968) [Trifluralin: Residues on Grapes and
Other Crops]. (Conpilation; unpublished study received Apr 8,
1969 under 9F0787; CDL:091358-A)
00105681 Little, C.; Bundy, D.; Hunt, H.; et al. (1969) Residue Data on
Trifluralin in Wheat. (Unpublished study received Jun 23, 1969
under 9F0851; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:091473-B)
00105683 Bundy, D.; Macy, T.; Hunt, H.; et al. (1969) Trifluralin: Pepper-
mint and Spearmint. (Unpublished study received Aug 4, 1969
under OF0862; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:091490-B)
00105689 Elanco Products Co. (1965) [Trifluralin Residues in Agronomic
Crops]. (Compilation; unpublished study received May 24, 1966
under 6F0493; CDL:092781-D)
00105690 Elanco Products Co. (1966) Carbon-14 Trifluralin Goat Feeding Ex-
periment. (Unpublished study received Jul 29, 1968 under
7F0565; CDL:092853-A)
00105691 Elanco Products Co. (1967) [Residue Data for Trifluralin in Al-
falfa]. (Compilation; unpublished study received Feb 6, 1967
under 7F0565; CDL:092853-B)
00105695 Holzer, F. (1969) Determination of Trifluralin Residues in Mint
Oil: Procedure 5801577. (Unpublished study received Aug 4, 1969
under OF0862; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:093159-A)
00105696 Eli Lilly and Co. (1974) Residue Data on Treflan 4 EC When Used
for Weed Control in Established Asparagus. (Unpublished study
received on unknown date under 4G1501; submitted by Elanco
Products Co., Div. of Eli Lilly and Co., Indianapolis, IN;
CDL:093981-A)
280
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00105697 U.S. Dept. of Agriculture (1973) [Treflan Residues in Corn and
Soil]. (Conpilation; unpublished study received May 23, 1974
under 4E1509; CDL:094632-A)
00105702 Frank, R.; Johnson, W. (1976) Residue Data on Trifluralin in Aspar-
agus When Incorporated into the Soil as a 4EC Formulation. (Un-
published study received Dec 14, 1978 under 1471-35; submitted
by Blanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:097696-B)
00105704 Frank, R.; Sieck, R.; Shuey, E. (1979) Trifluralin in Barley and
Grain Sorghum When Postplant Soil Incorporated: Residue Data.
(Unpublished study received Feb 7, 1979 under 1471-35; submitted
by Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:097790-A)
00105710 Johnson, W.; Griggs; Turner (1975) Residue Data on Trifluralin and
Diphenamid When Trefmid Plus Dymid Is Preplant Soil Incorporated
for Weed Control in Direct-seeded Tomatoes. (Unpublished study
received Apr 28, 1975 under 1471-68; submitted by Elanco Prod-
ucts Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:
101101-A)
00105713 Elanco Products Co. (1963) [Residues of Trifluralin in Cottonseed].
(Conpilation; unpublished study-received May 13, 1963 under
1471-35; CDL:101591-A)
00105716 Scroggs, R. (19??) Undated letter sent to R. Hill: Stability
of trifluralin in cottonseed (raw agricultural commodity).
(Unpublished study received May 21, 1964 under 1471-35; sub-
mitted by Elanco Products Co., Div. of Eli Lilly and Co., In-
dianapolis, IN; CDL: 101598-A)
00105717 Johnson, W.; Thornton, J.; Schumann, S.; et al. (1973) Residue
Data on Treflan E.G. and Sencor SOW When Tank-mixed for Weed
Control in Soybeans. (Unpublished study received Nov 28, 1973
under 1471-35; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:101604-A)
00105720 Elanco Products Co. (1964) General Summary: [Treflan E.G.]. (Com-
pilation; unpublished study received May 7, 1964 under 1471-35;
CDL:101595-A)
281
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trif luralin Standard
MRID CITATION
00105724 Bundy, D.; Griggs, D.; Little,'C.; et al. (1968) Residue Data on
Trifluralin in Collard, Kale, Mustard, and Turnip Greens. (Un-
published study received Aug 26, 1968 under 1471-35; submitted
by Blanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:101679-A)
00105725 Hunt, H. (1970) Residue Data on Trifluralin as a Preplant Applica-
tion for Control of Rhizome Johnsongrass in Soybeans. (Unpub-
lished study received Feb 3, 1971 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:101680-A)
00105726 Johnson, W.; Oliva, M.; Macy, T.; et al. (1973) Residue Data on
Treflan Applied by Subsurface Injection for Bindweed Control.
(Unpublished study received Jul 26, 1974 under 1471-35; submit-
ted by Elanco Products Co., Div. of Eli Lilly and Co., Indianap-
olis, IN; CDL:101681-A)
00105727 Hunt, H. (1970) Trifluralin for Pre-emergence Weed Control in
Sugarcane When Surface Applied in Hawaii (Experimental Permit).
(Unpublished study received May 11, 1971 under 1471-35; submit-
ted by Elanco Products Co., Div. of Eli Lilly and Co., Indianap-
olis, IN; CDL:101682-A)
00105729 Johnson, W.; Turner, L.; Macy, T.; et al. (1973) Residue Data on
Treflan as a Preplant Application for Rhizome Johnsongrass Con-
trol in Cotton. (Unpublished study received Sep 26, 1973 under
1471-35; submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, IN; CDL:101683-A)
00105730 Johnson, W.; Oliva, M.; Bewley, G.; et al. (1974) Residue Data on
Treflan 4EC for Preemergence Control of Weeds in Stubble (Ra-
toon) Sugarcane, as a Layby Application for Plant Sugarcane, and
for the Control of Raoulgrass (Itchgrass) in Sugarcane (Louisi-
ana and Texas). (Unpublished study received Aug 28, 1974 under
1471-35; submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, IN; CDL:101684-A)
00105731 Elanco Products Co. (1965) Treflan for Pre-emergence Weed Control
in Cotton: Research Data. (Compilation; unpublished study re-
ceived May 27, 1965 under 1471-35; CDL:101685-A)
00105733 Johnson, W.; Oliva, M. (1973) Residue Data on Treflan as a Post-
emergence Treatment for Weed Control in Potatoes. (Unpublished
study received Aug 31, 1973 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lily and Co., Indianapolis, IN;
CDL:101688-A)
282
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00105734 Johnson, W.; Oliva, M. (1973) Residue Data on Treflan Preplant and
Postplant Application for Weed Control in Potatoes. (Unpub-
lished study received Aug 31, 1973 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:101689-A)
00105735 Johnson, W.; Oliva, M.; Macy, T.; et al. (1973) Residue Data on
Treflan EC for Weed Control in Gearing Plum and Prune Trees.
(Unpublished study received Mar 6, 1974 under 1471-35; submitted
by Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:101690-A)
00105746 Cole, P.; Miller, D.; Purvis, A.; et al. (1975) Residue Data on
Trifluralin EC Applied at Increased Rates as a Tank-mix with
Metribuzin WP for Weed Control in Soybeans. (Unpublished study
received Jun 11, 1975 under 1471-r35; submitted by Elanco Prod-
ucts Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:
115267-A)
00105749 Scholz, N. (1964) Residue'Data on Trifluralin in Green Beans, Lima
Beans, Dry Beans, Southern Peas, Broccoli, Brussels Sprouts,
Cabbage, and Cauliflower. (Unpublished study received Jan 4,
1965 under 1471-35; submitted by Elanco Products Co., Div. of
Eli Lilly and Co., Indianapolis, IN; CDL:119193-A)
00105750 Eli Lilly and Co. (1964) Residue Data on Trifluralin in Safflower,
Okra, and Transplant Tomatoes and Peppers. (Unpublished study
received Jan 4, 1965 under 1471-35; submitted by Elanco Products
Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:119195-A)
00105751 Elanco Products Co. (1964) Summary: [Trifluralin]. (Compilation;
unpublished study received May 21, 1964 under 1471-35; CDL:
119196-A)
00105755 Johnson, W. (1975) Residue Data on Trifluralin Plus Triallate
When Tank-mixed and Preplant Soil Incorporated for Weed Control
in Peas. (Unpublished study received Jul 16, 1975 under 1471-
35; submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, IN; CDL:123535-A)
00105757 Elanco Products Co. (1965) [Treflan for Weed Control in Sugar
Beets]. (Compilation; unpublished study received Mar 10, 1965
under unknown admin, no.; CDL:126630-A)
00105759 Elanco Products Co. (1963) General Summary: [Trifluralin Studies].
(Compilation; unpublished study received Oct 10, 1963 under
1471-35; CDL:119190-A; 120368; 119194)
283
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to. be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00105772 Blanco Products Co. (1975) Trif luralin ...: PR Notice 70-15 Data.
(Conpilation; unpublished study received Jul 16, 1975 under
1471-35; CDL:222334-A)
00105776 Consultox Laboratories Ltd. (1974) Trifluralin Acute Oral and
Dental ToxLcity Evaluation: CL74: 101: 1051A. (Unpublished
study received Jul 23, 1975 under 33660-3; submitted by
Industria Prodotti Chimici, S.p.A., Novate Milanese, Italy; CDL:
224066-B)
00105780 Elanco Product Co. (1977) Treflan EC Plus Caparol SOW Tank-mix Pre-
plant Soil Incorporated on Cotton in California, Arizona, New
Mexico and Texas. (Conpilation; unpublished study received Aug
2, 1977 under 1471-35; CDL:230951-A)
00105781 Addison, D.; Grant, D.; Keaton, J.; et al. (1977) Treflan EC Plus
Cotoran SOW Tank-mixed and Preplant Soil Incorporated for Weed
Control in Cotton (Except California and Arizona). (Unpub-
lished study received Aug 2, 1977 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:230952-A)
00120263 Decker, 0.; Sieck, R.; Shuey, E. (1980) Residues of Trifluralin in
Onions When Used as a Popi Treatment for Weed Control. (Unpub-
lished study received Dec 9, 1982 under 1471-35; submitted by
Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:248981-A)
00124904 West, S.; Day, E.; Amundson, M. (1977) Residues of N-Nitrosodipro-
pylamine and Trifluralin in Crops from Fields Treated with Tre-
flan: Pre-RPAR Review Submission #8. (Unpublished study re-
ceived Dec 21, 1977 under 1471-35; submitted by Elanco Products
Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:233223-C)
00124905 Amundson, M.; Berard, D. (1977) Uptake, Distribution, and Trans-
formation of N-Nitrosodipropylamine by Soybean Plants: A Sum-
mary: Pre-RPAR Review Submission #8. (Unpublished study re-
ceived Dec 21, 1977 under 1471-35; submitted by Elanco Products
Co., Div. of Eli Lilly and Co., Indianapolis, IN; CDL:233223-D)
00125299 Berard, D. (1977) Absorption of 14C N-Nitrosodipropylamine by
Soybean Plants from Soil: [Submission at EPA/OSPR Meeting].
Prelim, rept. (Unpublished study received Aug 11, 1977 under
1471-35; submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, IN; CDL:233239-B)
284
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00125303 West, S.; Day, E. (1978) The Determination of Volatile Nitrosamines
in Crops and Soil Treated with Dinitroaniline Herbicides:
Pre-RPAR Review Submission #13. (Presented at the ACS; Mar
17, 1978; unpublished study received Mar 9, 1978 under 1471-35;
submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, IN; CDL:233245-A)
00126661 Oberly, T.; Emerson, J.; Bewsey, B.; et al. (1983) The Effect of
Trifluralin (Compound 36352) on the Induction of Forward
Mutation at the Thymidine Kinase Locus of L5178Y Mouse Lymphoma
Cells: Study 830201MLA2055. (Unpublished study received Apr 5,
1983 under 1471-70; submitted by Elanco Products Co., Div. of
Eli Lilly and Co., Indianapolis, IN; CDL:249846-C)
00128308 Decker, 0.; Sieck, R.; Shuey, E. (1983) Trifluralin Residue Data
in Mature Soybean Seed When Treflan Is Applied PPI or PPI Plus
LBI at Elevated Rates for Itchgrass Suppression: I-ODD-83-03.
(Unpublished study received May 6, 1983 under 1471-35; submitted
by Elanco Products Co., Div. of Eli Lilly and Co., Indianapolis,
IN; CDL:250106-A)
00129059 Hoyt, J.; Markham, J.; Johnson, W.; et al. (1983) A Dominant Lethal
Study with Technical Trifluralin (Compound 36352) in the Wistar
Rat: Study R00283. (Unpublished study received Jun 27, 1983 un-
der 1471-70; submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, IN; CDL:250598-A)
00131132 Fink, R.; Beavers, J.; Brown, R. (1978) One-generation Reproduction
Study—Mallard Duck: Compound 36352, Trifluralin: Project
No. 151-103. Final Rept. (Unpublished study received Sep 20,
1983 under 1471-70; prepared by Wildlife International Ltd.,
submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, IN; CDL:251256-A)
00131134 Fink, R.; Beavers, J.; Brown, R. (1979) One-generation Reproduction
Study—Bobwhite Quail: Compound 36352, Trifluralin: Project
No. 151-102. Final rept. (Unpublished study received Sep 20,
1983 under 1471-70; prepared by Wildlife International Ltd.,
submitted by Elanco Products Co., Div. of Eli Lilly and Co., In-
dianapolis, IN; CDL:251256-C)
00131135 Mosier, J.; Saunders, D. (1978) A Hydrolysis Study on the Herbicide
Trifluralin. (Unpublished study received Sep 20, 1983 under
1471-70; submitted by Elanco Products Co., Div. of Eli Lilly and
Co., Indianapolis, IN; CDL:251257-A)
285
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00133939 Elanco Products Co. (1975) Residue Data on Trifluralin plus EPTC
Tank-mixed and Preplant Soil Incorporated for Weed Control in
Potatoes Grown in Idaho, Oregon and Washington (Full Registra-
tion) . (Compilation; unpublished study received Jul 16, 1975
under 1471-35; CDL: 224180-A.)
00134326 Worth, H.; Adams, E.; Markham, J.; et al. (1977) A Modified Suba-
cute Toxicity Study with Trifluralin: [Rats]: Study R-1265.
(Unpublished study received Oct 11, 1979 under 1471-35; submit-
ted by Elanco Products Co., Div. of Eli Lilly and Co., Indianap-
olis, IN; CDL:241134-C)
00137468 Negilski, D.; Eranerson, J.; Authur, B.; et al. (1984) Guinea Pig
Sensitization Study of Treflan 10G, a Granular Formulation
(FN-1199) Containing 10% Trifluralin: Study G01483. (Unpub-
lished study received Jan 19, 1984 under 1471-143; submitted
by Elanco Products Co., Div. of Eli Lilly and Co., Indianapo-
lis, IN; CDL:252198-A)
00137573 Cochrane, R.; Hudson, H.; Emmerson, J.; et al. (1983) The Toxicity
of Trifluralin (Compound 36352) to Bobwhite in a Fourteen-day
Acute Oral Study: Study A02383. (Unpublished study received Feb
16, 1984 under 1471-70; submitted by Elanco Products Co., Div.
of Eli Lilly and Co., Indianapolis, IN; CDL:252411-A)
00138224 Mattingly, C.; Emnerson, J.; Arthur, B.; et al. (1984) Guinea Pig
Sensitization Studies of Trifluralin, Compound 36352: Studies
G01083 and G01483. (Unpublished study received Apr 5, 1984 un-
der 1471-70; submitted by Elanco Products Co., Div. of Eli Lilly
and Co., Indianapolis, IN; CDL:252949-A)
00138857 Kehr, C.; Emnerson, J.; Brannon, D.; et al. (1983) The Toxicity of
Trifluralin (Compound 36352) to Bobwhite in a Five-day Dietary
Study: Study 7016-77. (Unpublished study received Jan 24, 1984
under 1471-70; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:252283-A.)
00138858 Kehr, C.; Emmerson, J.; Brannon, D.; et al. (1983) The Toxicity of
Trifluralin (Compound 36352) to Mallards in a Five-day Dietary
Study: Study 7018-77. (Unpublished study received Jan 24, 1984
under 1471-70; submitted by Elanco Products Co., Div. of Eli
Lilly and Co., Indianapolis, IN; CDL:252283-B)
286
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00152419 Byrdf R. (1984) A Teratology Study of Trifluralin (El-152,
36352) Administered Orally to Charles River CD Rats: Study
R08484. Unpublished study prepared by Lilly Research Labs.
308 p.
00152420 Byrd, R. (1984) A Teratology Study (I) of Trifluralin (El-152, Com-
pound 36352) Administered Orally to Dutch Belted Rabbits: Study
B02283. Unpublished study prepared by Lilly Research Labs.
131 p.
00152421 Byrd, R. (1984) A Teratology Study (II) of Trifluralin (El-152,
Compound 36352) Administered Orally to Dutch Belted Rabbits:
Study B01784. Unpublished study prepared by Lilly Research
Labs. 223 p.
00155261 Leist, K. (1981) Four Hour LC50 Aerosol Inhalation Toxicity Study
in Rats on HOE 38474 OH at 210 Active Ingredient (Technical):
Report: Project 005477. Unpublished study prepared by Research
& Consulting Co. Ltd. 37 p.
00155972 Elanco Products Co. (1985) Trifluralin Ecological Effects Field
Monitoring Study and Related Laboratory Tests: Studies V00184,
F03085, F10883, and F00385: Executive Summary. Unpublished study.
5 p.
00155973 Francis, P.; Cocke, P. (1985) Bioavailability of Sediment-sorbed
Trifluralin to Bluegill under Laboratory Conditions: Study
F03085. Unpublished study prepared by Lilly Research Laboratories,
99 p.
00155974 Francis, P.; Jordan, W.; Grothe, D. (1985) Vertebral Column Lesions
and Tissue Residues in Brown Trout (Salmo trutta) Exposed to
Trifluralin for 24 Hours: Study V10883. Unpublished study
prepared by Lilly Research Laboratories. 90 p.
00155975 Francis, P.; Jordan, W. (1985) The Effect of Spinal Transection on
the Occurrence of Vertebral Lesions in Brown Trout (Salmo
trutta) Exposed to Trifluralin: Study F00385. Unpublished
study prepared by Lilly Research Laboratories. 59 p.
00155978 Francis, P.; Grothe, D.; Jordan W., et al. (1985) Trifluralin
Ecological Effects Field Monitoring Study: Study V00184.
Unpublished study prepared by Lilly Research Laboratories. 419 p.
287
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
00157482 Vigna E. (1985) Trifluralin Technical: Acute Dermal Toxicity Study
in Rats: RBM Exp. No. 2159. Unpublished study prepared by Isti-
tuto di Ricerche Biomediche "Antoine Marxer", RBM S.p.A. 13 p.
00157483 Vigna, E. (1985) Trif luralin Technical: Acute Eye Irritation Study
in Rabbits: RBM Ex. No. 2160. Unpublished study prepared by
Istituto di Ricerche Biomediche "Antoine Marxer", RBM S.p.A.
15 p.
00157484 Bassi, L. (1985) Trifluralin Technical: Dermal Sensitization Study
in Guinea Pigs: RBM Exp. No. I 892. Unpublished study prepared
by Istituto di Ricerche Biomediche "Antoine Marxer", RBM S.p.A.
00157485 Vigna, E. (1985) Trifluralin Technical: Acute Dermal Irritation
Study in Rabbit: RBM Ex. No. 2161. Unpublished study prepared
by Istituto di Ricerche Biomediche "Antoine Marxer", RBM
S.p.A. 13 p.
00157486 Vigna, E. (1985) Trifluralin Technical: Acute Toxicity Study by
Oral Route in Rats: RBM Exp. No. 2162 Unpublished study pre-
pared by Istituto di Ricerche Biomediche "Antoine Marxer", RBM
S.p.A. 13 p.
00162543 Hoyt, J. (1986) A One-year Two-generation Reproduction Study in
CD Rats Maintained on Diets Containing Trifluralin (EL-152, Com-
pound 36352): Studies R06384 and R13984. Unpublished study
prepared by Lilly Research Laboratories. 778 p.
05001991 Stevenson, J.H. (1978) The acute toxicity of unformulated
pesticides to worker honey bees (Apis mellifera). Plant
Pathology 27(1):38-40.
05008271 Macek, K.J.; Lindberg, M.A.; Sauter, S.; Buxton, K.S.: Costa, P.A.
(1976) Toxicity of Four Pesticides to Water Fleas and Fathead
Minnows. Duluth, Minn.: U.S. Environmental Protection Agency,
Environmental Research Laboratory. (EPA report no.
EPA-600/3-76-099; available from: NTIS, Springfield, VA; PB-262
912)
GS0144-012 Johnson, W.; Finley, M. (1980) Handbook of Acute Toxicity of
Chemicals to fish and Aquatic Invertebrates. USDI Publication
137, Washington, D.C.
288
-------
OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Trifluralin Standard
MRID CITATION
GS0179-001 Biswas, P; Hamilton, W. (1969) Metabolism of trifluralin in peanuts
and sweet potatoes. Weed Science 17:206-221.
GS0179-002 Wolff, J. (1967) Memorandum dated June 14, 1967 to Petitions
Control Branch and Division of Toxicological Evaluation,
FDA: In Petition 7F0555.
GS0179-009 Hooks, J. (1984) Interim Report of Nov. 2, 1984 for a [2]
Generation [Reproduction] Study in Charles River CD Rats
Given Trifluralin in the Diet. Unpublished summary. 1 p.
GS9999-001 Hudson, R; Tucker R.; Haegele M. (1984) Handbook of Toxicity of
Pesticide to Wildlife. USDI Publication 153.
Washington, D.C.
289
-------
OFFICE OF PESTICIDE PROGRAMS
ADDENDUM TO THE BIBLIOGRAPHY FOR TRIFLURALIN
Studies Not Reviewed for Trifluralin Standard
MRID CITATION
00148318 Young, R. (1984) Evaluation of Triflurex Technical (Trifluralin)
in the CHO/HCPRT Forward Mutation Assay: Final Report: LBI Project
No. 22207. Unpublished study prepared by Litton Bionetics, Inc.
27 p.
00148319 Moore, M. (1984) Evaluation of Triflurex Technical in the Rat
Dominant Lethal Assay: Final Report: Project No. 22203.
Unpublished study prepared by Litton Bionetics. 69 p.
00148320 Ivett, J. (1984) Mutagenicity Evaluation Triflurex Technical,
Batch No. 5320 in the Bone Marrow: Cytogenic Assay: Final •
Report: LBI Project No. 22202. Unpublished study prepared by
Litton Bionetics. 32. p.
00148345 Jagannath, D. (1984) Mutagenicity Evaluation of Triflurex Tech
(Trifluralin) Batch 5230 in the Ames Salmonella/Microsome Plate
Test: Final Report: LBI Project No. 20988. Unpublished study
prepared by Litton Bionetics, Inc. 19 p.
00149737 Borders, C.; Salamon, C. (1985) Teratology Study in Albino Rats
with Triflurex Technical: Study No. 450-1550. Unpublished study
prepared by Toxigenics, Inc. 246 p.
00158237 Rubin, Y. (1986) Teratology Study in the Rabbit: Triflurex: Rept.
No. AGN/126/TRI. Unpublished study prepared by Life Science
Research Israel Ltd. 150 p.
290
-------
OFFICE OF PESTICIDE PROGRAMS
ADDENDUM TO THE BIBLIOGRAPHY FOR TRIFLURALIN
Studies Not Reviewed for Trifluralin Standard
MRID CITATION
00151894 Mellano, D. (1982) Study of the Capacity of the Test Article HOE
38474 OH at 208 to Induce "Unscheduled DNA Synthesis" in Cul-
tured Hela Cells: Study No. M 372. Unpublished study prepared by
Istituto Di Ricerche Biomediche "Antoine Marxer" S.p.A. 19 p.
00151895 Leist; Weigand; Kramer (1981) Testing of Hoe 38474 - Active Ingre-
dient for Mutagenicity in the Micronucleus Test following Oral
Administration to NMRI Mice: (Code: HOE 38474 OH AT 208): Report
No. 285/81. Unpublished report prepared by Hoechst Aktienge-
sellschaft. 16 p.
00151896 Horstmann (1984) Dominant-lethal Test for Determination of Muta-
genic Effect in Male NMRI-mice after Oral Adminstration: Tri-
fluralin: Code: Hoe 38474 OHZD99 0002: Report No. 84.0763. Un-
published report prepared by Hoechst Aktiengesellschaft. 89 p.
00151897 Fumero, S.; Berruto, G. (1982) In vivo Study of Chromosome Aberra-
tion in the Test Article HOE 38474 OH at 208 Administered by
Oral Route: Study No. M 373. Unpublished study prepared by
Istituto Di Ricerche Biomediche "Antoine Marxer" S.p.A. 24 p.
00151898 Fumero, S. (1982) Study of the Mutagenic Activity "In Vitro" of the
Compound HOE 38474 OH AT 208 with Schizosaccharomyces Pombe:
Study No. M 374. Unpublished study prepared by Institute Di
Ricerche Biomediche "Antoine Marxer" S.p.A. 16 p.
00151899 Baeder, Weigand, Kramer (1983) Testing for Embryotoxicity in Wister
Rats following Oral Administration: HOE 38474 - Active Ingre-
dient: Report No. 83.0557: Study NO.G2R0383. Unpublished study
prepared by Hoechst Aktiengesellschaft. 51 p.
00151900 Becker, H. (1984) Embryotoxicity Study with Trifluralin - Substance
Technical Grade (Code HOE 038474 OH ZD99 0002) in the Rabbit
(Oral Administration): Project No. 032387. Unpublished study
prepared by Research & Consulting Co., AG. 83 p.
00151901 Becker, H. (1984) Multiple Generation Study in the Rat: Trifluralin
Substance Technical Grade (Code : HOE 38474 OH AT210): Project
No. 008875. Unpublished study prepared by Research & Consulting
Co., AG. 604 p.
00151903 Westen, H. (1984) Multiple Generation Study in Rat: Trifluralin
Substance Technical Grade (Code: HOE 38474 0 H AT210): Pathology
Report Part II: Project No. 008875. Unpublished study prepared
by Research & Consulting Co., AG. 704 p.
291
-------
OFFICE OF PESTICIDE PROGRAMS
ADDENDUM TO THE BIBLIOGRAPHY FOR TRIFLURALIN
Studies Not Reviewed for Trifluralin Standard
MRID CITATION
00151904 Ullmann, L. (1982) 30 Day Repeated Dose Inhalation Toxicity Study
with HOE 38474 OH AT 210 Active Ingredient (Technical) in Rats:
Part 1: Project No. 005488. Unpublished study prepared by
Research & Consulting Co., Ltd. 400 p.
00151905 Suter, P. (1983) 13-Week Toxicity Study with Trifluralin (HOE 38474
0 H AT210) in Mice following Dietary Administration: Report:
Project No. 008842. Unpublished study prepared by Research &
Consulting Co., AG. 223 p.
00151906 Schutz; Weigand; Kraiter (1980) Repeated-dose (3 Months) Oral Toxi-
city Study of the Active Substance HOE 38474 (Code: HOE 38474
0 H AT204) Administered in the Feed to Rats: Report No. 618/80.
Unpublished study prepared by Hoechst Aktiengesellschaft.
422 p.
00151907 Brunk; Weigand; Kramer (1981) Toxicology Testing of Trifluralin
(Hoe 38474 OH AT 204) by Repeated Oral Administration to Beagle
Dogs for Six Months: Report No. 636/81. Unpublished report pre-
pared by Hoechst Aktiengesellschaft. 742 p.
00151908 Bathe, R. (1984) 12-Month Oral Toxicity (Feeding) Study
in Beagle Dogs: Trifluralin Substance Technical Grade (Code: HOE
38474 0 H AT210): Project No. 008864: Report Part 1. Unpu-
blished study prepared by Research & Consulting Co. 439 p.
00153496 Donaubauer; Schutz; Weigand (1983) Chronic Feeding Study in Rats:
(Interim Sacrifice at 12 Months): Trifluralin: Internal Interim
Report: Study No. 680. Unpublished study prepared by Hoechst
Aktiengesellschaft. 1131 p.
00155261 Leist, K. (1981) Four Hour LC50 Aerosol Inhalation Toxicity Study
in Rats on HOE 38474 OH at 210 Active Ingredient (Technical):
Report: Project 005477. Unpublished study prepared by Research
& Consulting Co. Ltd. 37 p.
00158935 Suter, P. (1986) Oncogenicity Study with Trifluralin Active Ingre-
dient Technical (HOE 38474 0 H AT210) in Mice: Project No.
008853. Unpublished study prepared by Research & Consulting
Company AG. 6478 p.
GS-0179-010 Donaubauer, et al (1986) Trifluralin: Combined Chronic Toxicity
and Carcinogenicity Study in Rats: Study No. 680.
Unpublished study prepared by Hoechst Aktiengesellschaft
Pharma Forschung Toxikologie. 5,198 p.
40138301 Emmerson, et al (1986) A Supplementary Report of a Study in
Fischer 344 Rats Maintained on Diets Containing Trifluralin
(Compound 36352) for Three Months: Study No R04785. Unpublished
study prepared by Lilly Research Laboratories. 262 p.
292
-------
APPENDIX V
FORMS APPENDICES
293
-------
OMB Aporovat No. 2000-G45a
FIFRA SECTION 3(C)(2H8) SUMMARY SHEET
EPA REGISTRATION NO.
PRODUCT NAME
APPLICANTS NAME
DATE GUIDANCE DOCUMENT ISSUED
With respect to the requirement to submit "generic" data imposed by the FIFRA section 3(C)(2)(B) notice contained in the referenced
Guidance Document, I am responding in the following manner:
D 1. I will submit data in a timely manner to satisfy the following requirements. If the test procedures I will use deviate from (or are not
specified in) the Registration Guidelines or the Protocols contained in the Reports of Expert Groups to the Chemicals Group, OECD
Chemicals Testing Programme, I enclose the protocols that I will use:
D 2. I have entered into an agreement with one or more other registrants under FIFRA section 3(C)(2)(B)(ii) to satisfy the following data
requirements. The tests, and any required protocols, will be submitted to EPA by:
\
NAME OF OTHER REGISTRANT '
D 3. I enclose a completed "Certification of Attempt to Enter Into an Agreement with Other Registrants for Development of Data" with
respect to the following data requirements:
LJ 4. I request that you amend my registration by deleting the following uses (this option is not available to applicants for new products):
5. I request voluntary cancellation of the registration of this product. (This option is not available to applicants for new products.)
REGISTRANT'S AUTHORIZED REPRESENTATIVE
SIGNATURE
DATE
EPA. Form 8580-1 (10-82)
-------
OMB Approval No. 2000-0468 .
(To Qualify, certify ALL four items)
CcnTJFlCATiCN OF ATTZVPT TO'S.'JTSS
INTO AN AGREEMENT WITH OTHER REGISTRANTS
FOR DEVELOPMENT OF DATA
t. I am duly authorized to represent the following firm(s) who are subject to the require-
ments of a Notice under FIFRA Section 3(c)(2)(B) contained in a Guidance Document
to submit data concerning the active ingredient:
GUIDANCE DOCUMENT DATE
ACTIVE INGREDIENT
NAME OF FIRM
EPA COMPANY NUMBER
(This firm or group of firms is referred to below as "my firm".)
2. My firm is willing to develop and submit the data as required by that Notice, if necessary. However, my firm would prefer to enter
into an agreement with one or more other registrants to develop jointly, or to share in the cost of developing, the following required
items or data:
1 My firm has offered in writing to enter into such an agreement Copies of the offers are attached. That offer was irrevocable and included an offer to be
Bound by an arbitration decision under FIFRA Section-3(c)(2)(BHiii) if final agreement on all terms could not be reached otherwise. This offer was made
to the following firm(s) on the following date(s):
NAME OF FIRM
DATE OF OFFER
However, none of those firm(s) accepted my offer.
4. My firm requests that EPA not suspend the registration(s) of my firm's product(s), if any of the firms named in paragraph (3) above
have agreed to submit the data listed in paragraph (2) above in accordance with the Notice. I understand EPA will promptly inform
me whether my firm must submit data to avoid suspension of its registration(s) under FIFRA Section 3(c)(2)(B). (This statement
does not apply to applicants for new products.) I give EPA permission to disclose this statement upon request.
TYPED NAME
SIGNATURE
DATE'
-------
FORMULATOR'S EXEMPTION STATEMENT
(40 CFR 152.85)
EPA File Symbol/Reg. No. Product Name
Applicant's Name-and Address
As an authorized representative of the applicant for registration of the
product identified above, I hereby certify that:
(1) This product contains the active ingredient(s):
(2) Each active ingredient listed in paragraph (1) is present solely
as the result of the incorporation into the product (during formulation or
packaging) of another product which contains that active ingredient, which
is registered under FIFRA sec. 3, and which is purchased bv us from another
producer.
(3) Indicate by circling (A) or (B) below which paragraph applies:
(A) An accurate Confidential Statement of Formula (EPA Form 8570-4) for
the above identified product is attached to this statement. That formula
statement indicates, by company name, registration number and product
name, the source of the active ingredient(s) listed in paragraph (1).
OR
(B) The Confidential Statement of Formula dated on file with
the EPA is complete, current and accurate and contains the information
required on the current CSF Fonr. No. 8570-4. The registered source(s)
of the active ingredient(s) listed in paragraph J1) is/are listed below:
Active ingredient Source: Product name and Reg. No.
Signature
Date ... Title
EPA Form (April 1985)
296
------- |