xvEPA United States Environmental Protection Agency Office of Pesticides and Toxic Substances Washington, DC 20460 EPA 560/7-81-014 July 1981 Toxic Substances Environmental and Health Aspects of Tetrachloroethylene A Comprehensive Bibliography of Published Literature 1930- 1981 ------- vvEPA OTS-TIC REPORT FILE United States Environmental Protection Agency Office of Pesticides and Toxic Substances Washington, DC 20460 EPA 68-01-6021 Rapt A July 1981 Toxic Substances Environmental and Health Aspects of Tetrachloroethylene A Comprehensive Bibliography of Published Literature 1930- 1981 ------- 50272-101 REPORT DOCUMENTATION ,i-_RETORT NO. i FPA 560/7-81-014 4. Title and Subtitle Environmental and Health Aspects of Tetrachloroethylene, A comprehensive Bibliography of Published Literature 1930-1981 7. Author(s) 3. Recipient's Accession No. 5. Report Date prepared June 1981 6. 8. Performing Organization Rept. No. 9. Performing Organization Name and Address Tracer Jitco, Inc. 1776 East Jefferson Street Rockville, Maryland 20852 I 10. Project/Task/Work Unit No. I ^Technical Directive 4 11. ComracUC) or Gr«nt(G) No. to 68*-01-5836 (G) 12- Sponsoring Organization Name and Address Environmental Protection Agency, Office of Pesticides and Toxic Substances, Management Support Division.. 401 M St., SW Washington, D.C. 20460 13. Type of Report A Period Covered Final Report 1930-1981 14. 15. Supplementary Notes 16. Ab»tr»ct (Limit: 200 words) This document is a bibliography of published citations on health and environmental aspects of Tetrachloroethylene (Chemical Abstracts Service Registry Number 127-17-4) for the period of 1930-1981. The citations have been selected from a thorough literature search, and broadly classified as having primarily environmental or biological emphasis. The sources used in the search are identified, and for the portion performed on line, the search strategies are also included. 17. Document Analysis a. Descriptors Bibliographies; Literature Surveys; Environments; Public Health Pollution; Toxicology. b. Identifiers/Open-Ended Terms Literature Search; Literature Review; Health Effects; Environmental Effects; 1,1,2 Trichloroethane; 79-00-5 c. COSATI Field/Group 18. Availability Statement 19. Security Class (This Report) Unclassified Release unlimited | 2O. Security Class (This Page) ' Unclassified 21. No. of Pages 22. Price I (See ANSI-239.181 See fnsfructions on Reverse OPTIONAL FORM 272 (*-77) (Formerly NTIS-35) Department of Commerce ------- EPA Report No. 560/7-81-014 July 1981 ENVIRONMENTAL AND HEALTH ASPECTS OF TETRACHLOROETHYLENE A Comprehensive Bibliography of Published Literature 1930 - 1981 by Management Support Division Information Support Services Branch Office of Toxic Substances Washington, D.C. 20460 68-06-5836 Project Officers Michael Weaver, Delores Evans Management Support Division Office of Toxic Substances Washington, D.C. 20460 OFFICE OF TOXIC SUBSTANCES U.S. ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20026 ------- Preface This bibliography was created from a literature search performed under the auspices of the Management Support Division, Information Support Services Branch for the Assessment Division, Chemical Review and Evaluation Branch; both of the Office of Toxic Substances. The search was intended to provide partial support for the preparation of a Preliminary Risk Assessment on tetrachloroethylene (127-18-4). This assessment reviews and evaluates the available significant economic and adverse effects data from both published and unpublished sources on a substance selected as being potentially hazardous to human health or the environment. The subject coverage of the assessment is broader than this bibliography which includes only published environmental and biological information. The bibliography does not include all information available to the review branch. Although it is not an authoritative source list for Preliminary Risk Assessments, it does represent a comprehensive and systematic search of the literature and subsequent selection of citations that pertain to health and the environment. The limits of the search are fully described in this document and its appendices. ------- Introduction 1. The Search This bibliography is a compilation of citations retrieved during a thorough review of the national and international literature on tetrachloroethylene (Chemical Abstracts Service Registry Number 127-18-4) cited between 1930 and April 1980. The supporting search was performed at the request of the Assessment Division/Chemical Review and Evaluation Branch by the Management Support Division/Information Support Services Branch, within the Office of Toxic Substances. 1.1. Scope To insure that the search was comprehensive, a variety of sources were examined, including the following: o On-line databases from major vendors of bibliographic information. o On-line databases from various agencies of the United States Government. o Manually searched national and international indices and abstract collections of scientific literature. o Reference sections of major review articles, criteria documents, monographs, and reports. o Selected handbooks. (A complete listing of sources consulted can be found in Appendices I and II). The emphasis of this bibliography is on the primary literature except for the handbook information presented in Section II and a few secondary sources selected because they contain unique or well-summarized information on the chemical. Subsequent to the main search, which was completed in April 1980, and using the same strategy, update searches were performed during the period from April 1980 to May 1981 on all the on-line databases initially searched. In addition, the April 1981 and May 1981 issues of Current Contents (Life Sciences, Agriculture, Biology, and Environmental Sciences series) were screened to retrieve citations which may not have been entered into the on-line files at the time of the final update searches. 11 ------- Because the overall requirement of the search request for this project was broader than the health and environmental aspects of the chemical, a wider range of databases was searched than might normally be expected for this bibliography. However, only health and environmental aspects were selected regardless of the data source examined. The total complement of databases searched is listed in the appendices for the user's reference. 1.2. Strategy The search requirement demanded high recall of information dealing with tetrachloroethylene; precision was a secondary consideration. EPA decided to retrieve all citations that contained the term tetrachloroethylene or its synonyms in any searchable fields and to select relevant citations by a manual screen. The Chemical Abstract Service registry number (CAS RN) and systematic names and synonyms that could be identified from CHEMLINE (National Library of Medicine); CHEMDEX (System Development Corporation); CHEMNAME, CHEMSEARCH, and CHEMSIS (Lockheed Information System); SANSS (NIH/EPA Chemical Information System); and RTECS (NIOSH Registry of Toxic Effects of Chemical Substances) were used in the search on databases. For on-line searching, the names were divided into significant fragments and entered according to the conventions of the individual databases. Chemical terms used in this search were as follows: CAS RN: 127-18-4 C2-C14 (MF) ethylene, tetrachloro- (SCI) ethene, tetrachloro- (9CI) Ankilostin Didakene Ethylene Tetrachloride Nema (VAN) Perchloroethylene Persec Tetracap tetrachloroethylene 1,1,2,2-te trachloroethylene tetrachlorethylene perchlorethylene tetrachloroethene Antisal 1 Tetraguer Fedal-un Tetraleno Tetropil Perclene Tetlen No additional modifiers or keywords were used to limit information retrieved in any database for this chemical because comprehensive retrieval was desired. Complete search strategies are listed in Appendix II. 111 ------- Use/application categories were not used as search terms because EPA decided to select only terms that specifically mentioned the chemical or its synonyms. Indexing policy, keyword entry, and abstracting techniques usually assure retrieval of specific information on individual chemicals if they are discussed significantly in general articles or reviews. The user can be assured, therefore, that each citation listed in this bibliography contains substantive information on the subject chemical. Manual sources, indices, and abstract collections usually employ their own unique indexing schemes for chemical information, so it is difficult to describe a standard search strategy for these information tools. However, in all cases, the most specific indexing terms available in the source were used to identify citations on the subject chemical. 1.3. Selection of Citations Citations were selected for inclusion in this bibliography based on their relevance to the following topics: o Toxicity — Adverse and toxic effects on any biological systems, structural and functional changes in organs and tissues of all vertebrate and invertebrate species, test methods used for determination of toxicity, and bioassay studies. o Physiology — Absorption, distribution, transport, metabolism, and elimination in all species; techniques for measurement of tissue and organ residues; interactions with endogenous substances. o Epidemiology — Exposure data, morbidity, and mortality rates for general and occupational populations. o Environmental Significance — Environmental distribution in air, soil, and water; sources of pollution; ecological effects on microorganisms, insects, plants, and wildlife; biodegradation and bioconcentration; analytical techniques for sampling and measurement in the environment. o Safety, Control, and Regulations — Disposal hazards; Federal, local, and international controls, recommendations, and regulations. These are the broad specifications for inclusion in this bibliography. Because any literature selection process involves subjectivity and judgement, precise definitions are difficult. The general guiding requirement for inclusion is that citations must pertain to the biological or environmental aspects of the chemical. The following information is not included in this bibliography: news items; brief announcements and Federal Register notices; reports of on-going research which have not yet been published or any other unpublished information; draft reports; and private communications. IV ------- 2. Organization of Bibliography This bibliography is organized into three major sections. 2.1. Section Titles Section I — Handbook information Section II — Citations from the primary literature Section III — Appendices listing specific sources used and exact search strategies employed 2.2. Citation Format In Section II citations from on-line and manually searched abstract collections are arranged alphabetically by author. Personal names are entered with the last name first followed by the first two initials. Second and third authors' names are separated from the first author and each other by a semicolon. Up to three personal names are used; if there are more than three authors, the remaining are listed as "et al." If an author has written more than one article, citations are arranged in ascending chronological order. If authors and date are identical, citations are arranged alphabetically by title of the article. Single author entries are listed first, followed by two, then three author entries. Patents are arranged alphabetically by assignee name. All government publications are listed by the sponsoring government agency. Government or corporate names are written in full form. No acronyms are used. The country of origin is listed first, followed by the organizational hierarchy of the sponsoring group listed in descending hierarchical order. If the performing organization or individual author is known, they are listed on separate lines below the government sponsor. Example: NIOSH publication: United States. Department of Health, Education and Welfare. Public Health Service. Center for Disease Control. National Institute for Occupational Safety and Health Tracor Jitco, Inc. Brown, R.A.; Smith S.S. Corporate documents with no specific author are listed in alphabetical order according to the first significant word of the organization name. e.g., DuPont de Nemours, E.I. and Company ------- 2.3. Literature Cited The following kinds of literature are cited in this bibliography: journal articles, government reports, patents, organization and corporate reports, books, manufacturer's literature, conference proceedings, and dissertations. In each case an attempt has been made to supply the user with enough information so that the hard copy of the document may be easily obtained. Journal titles are abbreviated according to the style in the Chemical Abstracts Service Source Index (CASSI), The American Chemical Society, Columbus, OH, 1980 and its corresponding guide, Bibliographic Guide for Editors and Authors, The American Chemical Society, Washington, DC, 1974. All foreign titles have been translated into English. Foreign language articles are indicated by the appropriate three letter language abbreviation in parentheses at the end of the source information. 2.4. Categorization of Citations In order to make this bibliography a more useful tool for separate user groups, most citations are marked with the category code E or H. E = Environmental Aspects, i.e., the major content of the document pertains to the chemical in the open environment: its distribution, degradation, environmental chemistry and analysis; effect on ecosystems; effect on flora and fauna, including laboratory research, when emphasis is on environmental considerations rather than prediction of human effects, environmental chemistry, and analysis. H = Health Aspects, i.e., the major content of the document concerns known health effects, predictive laboratory research, and animal studies as relates to human health effects, human exposure, and epidemiological studies. A decision was made based on the abstract, and in some cases the entire document, to categorize according to what appeared to be the major purpose of the study. In a few cases neither category applies. Those citations were left unclassified. VI ------- HANDBOOK AND DATABANK INFORMATION ------- 3. Handbook and Databank Information 3.1. Summary Databanks for Health Effects Data (Information found) United States. Department of Health and Human Services. Public Health Service. Center for Disease yes Control. National Institute for Occupational Safety and Health Registry of Toxic Effects of Chemical Substances. Cincinnati, OH: NIOSH, 1980 United States. Department of Health and Human Services. Public Health Service. National Institutes of Health. National Library of Medicine yes Toxicology Data Bank. Bethesda, MD 1980 ------- 3.2. Handbooks Searched for Health Effects Source Browning, E. Toxicity and Metabolism of Industrial Solvents. New York: Elsevier Publishing Co., 1963 Location of Information pp. 213-9 Browning, E. Toxicity of Industrial Metals. New York: Appleton-Century-Crofts, 1969 No pertinent information found Dittmer, D.S., Editor Handbook of Toxicology, V. - Fungicides. Philadelphia: W. B. Saunders Company, 1959 pp. 76-7 Fishbein, L. Potenial Industrial Carcinogens and Mutagens. New York: Elsevier Scientific Publishing Co., 1979 pp. 187-9, 193, 245 Fishbein, L.; Flamn, W.6.; Falk, H.L. Chemical Mutagens. New York: Academic Press, 1970 No pertinent information found Goodman, L.S.; Oilman, A., Editors The Pharmacological Basis of Therapeutics. New York: Macmillan Publishing Co., Inc., 1975 pp. 1026, 1646 Patty, F.A., Editor Industrial Hygiene and Toxicology. New York: Interscience Publishers, 1963 pp. 1314-7 Plunkett, E.R. Handbook of Industrial Toxicology. New York: Chemical Publishing Co., Inc., 1976 pp. 394-5 Sax, N.I. Dangerous Properties of Industrial Materials. New York: Van Nostrand Reinhold Co., 1979 p. 892 Searle, C.E., Editor Chemical Carcinogens. Washington, DC: American Chemical Society, 1976 No pertinent information found ------- 3.2. Handbooks Searched for Health Effects (cont'd) Source Shepard, T.H. Catalog of Teratogenic Agents. Baltimore, MD: The Johns Hopkins University Press, 1976 Location of Information No pertinent information found Spector, W.S., Editor Handbook of Toxicology, V. I. - Acute Toxicities. Philadelphia: W. B. Saunders Company, 1956 p. 350 Spector, W.S., Editor Handbook of Toxicology, V. II. - Antibiotics. Philadelphia: W.B. Saunders Company, 1957 No pertinent information found Spector, W.S., Editor Handbook of Toxicology, V. III. - Insecticides. Philadelphia: W.B. Saunders Company, 1959 pp. 736-8 Sunshine, I., Editor CRC Handbook Series in Analytical Toxicology. Boca Raton, FL: CRC Press, Inc., 1979 pp. 660-1 United Nations. International Agency for Research on Cancer IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Lyon, France: IARC Vol. 20, pp. 491-505 United States. Department of Health and Human Services. Public Health Service. Center for Disease Control. National Institute for Occupational Safety and Health NIOSH Criteria Documents. Cincinnati, OH: NIOSH pp. 76-185 United States. Department of Health and Human Services. Public Health Service. National Institutes of Health. National Cancer Institute NCI Carcinogens Bioassay Reports. Springfield, VA: National Technical Information Service Entire document ------- 3.2. Handbooks Searched for Health Effects (cont'd) Source Location of Information United States. Department of Health and Human Suppl. I, Services. Public Health Service. National Institutes p. 221 of Health. National Cancer Institute Survey of Compounds Which Have Been Tested for Carcinogenic Activity. Bethesda, MD: NCI, 1978 United States. Environmental Protection Agency p. 211 EPA Publications Bibliography. Washington, DC, EPA (1979) ------- 3.3. Handbooks Searched for Environmental Effects Source Applegate, V.C.; Howe11, J.H.; Hall, A.E.; et al. Toxicity of 4,346 Chemicals to Larval Lampreys' and Fishes: Special Scientific Report. Fisheries No. 207, Washington, DC, 1957 Location of Information No pertinent information found McKee, J.E.; Wolf, H.W., Editors Water Quality Criteria, 2nd Edition. California State Water Resources Control Board, 1963 No pertinent information found Ryckman, D.W.; Prabhakara Rao, A.V.S.; Buzzel, J.C. Behavior of Organic Chemicals in the Aquatic Environment. Washington, DC: Manufacturing Chemists' Association, 1966 No pertinent information found United States. Environmental Protection Agency Review of the Environmental Fate of Selected Chemicals. Springfield, VA: National Technical Information Service, 1977 No pertinent information found United States. Environmental Protection Agency Review of the Environmental Fate of 129 Priority Pollutants. Springfield, VA: National Technical Information Service, 1977 Chap. 53 Verschueren, K. Handbook of Environmental Data on Organic Chemicals. New York: Van Nostrand Reinhold Co., 1977 pp. 580-2 ------- 3.4. Handbooks Searched for Physical and Chemical Properties Source Aldrich Chemical Company, Inc. Aldrich Catalog Handbook of Fine Chemicals. 1981-2. Milwaukee, WI: Aldrich Chemical Co., 1980 Location of Information p. 781 Bennet, H., Editor Concise Chemical and Technical Dictionary. New York: Chemical Publishing Co., Inc., 1974 p. 205 Dreisback, R.R. Physical Properties of Chemical Compounds. Washington, DC: American Chemical Society, 1959 p. 411 Grasselli, J.G.; Ritchey, W.M., Editors CRC Atlas of Spectral Data and Physical Constants for Organic Compounds. Boca Raton, FL: CRC Press, 1975 p. 282 Grayson, M., Editor Kirk-Othmer Encyclopedia of Chemical Technology. New York: Interscience Publishers, 1979 No pertinent information found Hawley, G.G. The Condensed Chemical Dictionary. New York: Van Nostrand Reinhold Co., 1977 p. 660 Kortum, G.; Vogel, W. Dissociation Constants of Organic Acids in Aqueous Solution. London: Butterworths, 1961 No pertinent information found Leo, A.; Hansch, C.; Elkins, D. Chemical Reviews. Claremont, CA: Department of Chemistry, Pomona College, 1971 No pertinent information found Linke, W.F. Solubilities of Inorganic and Metal-Organic Compounds. New York: D. Van Nostrand Co., Vol. I. 1958, Vol. II. 1965 No pertinent information found ------- 3.4. Handbooks Searched for Physical and Chemical Properties (cont'd) Source Mark, H.F.; Gaylord, N.G.; Bikales, N.M., Editors Encyclopedia of Polymer Science and Technology. New York: Interscience Publishers, 1964 Location of Information No pertinent information found Perry, R.H.; Chilton, C.H., Editors Chemical Engineers Handbook. New York: McGraw-Hill Book Co., 1973 Chap. 3, p. 43 Pollock, J.R.; Stevens, R., Editors Dictionary of Organic Compounds. London: Eyre and Spottiswoode Publishers, Ltd., 1965 p. 2967 Stephen, H.; Stephen, T.; Editors Solubilities of Inorganic and Organic Compounds. New York: The Macmillan Co., 1963 No pertinent information found Weast, R.C., Editor CRC Handbook of Chemistry and Physics. Boca Raton, FL: CRC Press, 1979 p. 292 Windholz, M., Editor The Merck Index. Rahway, NJ: Merck and Co., Inc., 1976 p. 1184 ------- CITATIONS FROM THE LITERATURE ------- Abedin, Z.; Cook, R.C.; Milberg, R.M. H Cardiac Toxicity of Perchloroethylene (A Dry-Cleaning Agent). South. Med. J., 73(8):1081-3 (1980)' Adams, E.M.; Irish, D.D.; McCollister, D.D.; et al. H The Comparative Vapor Toxicity of Ethylene Bichloride, Trichloroethylene, Tetrachloroethylene, and Carbon Tetrachloride. Conference: Annual Meeting of the American Industrial Hygiene Association. Apr. 27, 1950 (Unpublished Paper) Akhmetov, F.Sh.; Guseinov, M.M.; Mamedov, D.V.; et al. E Destructive Oxidative Chlorination of a Mixture of Wastes from the Production of Allyl Chloride and Epichlorohydrin. Khim. Prom-st., (12):720-1 (1979) (Rus) Alani, M.D. H Studies on the Induction of Allergic Photodermatitis in Newborn Guinea Pigs. Acta Allergol., 27(l):50-4 (1972) Alberti, J. E Changes in Rhine Water Quality. Gewaesserschutz, Wasser, Abwasser, 42:243-70 (1980) (Ger) Alexander, H.C.; McCarty, W.M.; Bartlett, E.A. E Toxicity of Perchloroethylene, Trichloroethylene, 1,1,1-Trichloroethane, and Methylene Chloride to Fathead Minnows. Bull. Environ. Contain. Toxicol., 20(3):344-52 (1978) Allison, S.C.; Doran, M.; John, W.R.; et al. H Preliminary Investigation of Levels of Airborne Solvents and Other Conditions Found in Nine Coin Operated Dry Cleaning Establishments. Environ. Health, pp. 59-62 (Mar. 1976) Aluraot, E.; Nachtomi, E.; Mandel, E.; et al. H Tolerance and Acceptable Daily Intake of Chlorinated Fumigants in the Rat Diet. Food Cosmet. Toxicol., 14(2):105-10 (1976) American Conference of Governmental Industrial Hygienists H Hygienic Guide Series. Am. Ind. Hyg. Assoc. J., 21:265-71 (1960) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1961. Ind. Hyg. Digest, 25(7):II (1961) 11 ------- American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1962. Ind. Hyg. Digest, 26(10):III (1962) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1963. Ind. Hyg. Digest, 27(9):VIT (1963) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1964. Ind. Hyg. Digest, 28(9) :IV (1964) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1965. Ind. Hyg. Digest, 29(9):V (1965) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: .Threshold Limit Values (TLVs) for 1966. Ind. Hyg. Digest, 30(9):IV (1966) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1967. Ind. Hyg. Digest, 31(9):IV (1967) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for 1968. Ind. Hyg. Digest, 32(9):VII (1968) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for Airborne Contaminants Adopted by ACGIH for 1969 and Intended Changes. Ind. Hyg. Digest, 33(9):VIII (1969) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for Airborne Contaminants Adopted by ACGIH for 1970 and Intended Changes. Ind. Hyg. Digest, 34(11):VIII (1970) 12 ------- American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values (TLVs) for Airborne Contaminants Adopted by ACGIH for 1971 and Intended Changes. Ind. Hyg. Digest, 35(11):XIII (1971) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Documentation of the Threshold Limit Values for Substances in Workroom Air, 3rd edition, p. 201-2 Cincinnati, OH: Am. Conf. Gov. Ind. Hyg? (1971) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values TLVs for Substances in Workroom Air. Ind. Hyg. Digest, 36(10):VIII (1972) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values TLVs for Substances in Workroom Air. Ind. Hyg. Digest, 37(10):XI (1973) American Conference of Governmental Industrial Hygienists H Perchloroethylene. In: Threshold Limit Values TLVs for Chemical Substance and Physical Agents in the Workroom Environment with Intended Changes for 1979. p. 25 Cincinnati, OH: Am. Conf. Gov. Ind. Hyg. (1979) American National Standards Institute H Acceptable Concentrations of Tetrachloroethylene. U.S.A. Standards Committee on Acceptable Concentrations of Toxic Dusts and Gases, U.S.A. Standards Institute, New York, Report No. USAS Z37.22-1967, 8 pp. (1967) Ananina, T. H Effect of Aliphatic Hydrocarbons and Fluorinated and Chlorinated Derivatives on the Content of Nucleic Acids and Animal Tissues during Embryogenesis. Tr. Permsk. Cos. Med. Inst., 110:69-71 (1972) (Rus) Anderson, R.A.; Harland, W.A. H The Analysis of Volatiles in Blood from Fire Fatalities. Proceedings: Forensic Toxicol., Proceedings of the European Meeting of International Association of Forensic Toxicol., 1979. pp. 279-92 (1980) Andersson, H.F.; Dahlberg, J.A.; Wettstrom, R. H Phosgene Formation during Welding in Air Contaminated with Perchloroethylene. Ann. Occup. Hyg., 18(2):129-32 (1975) 13 ------- Andresen, U.; Oertel, S. E Determination of Tetrachloroethylene in Effluents from Textile Cleaning and Finishing. Textileinigung (Leipzig), 26(7):214-5 (1979) (Ger) Angerer, J.; Haag, A.; Szadkowski, D.; et al. A New Method for the Analysis of Ultra-micro Constituents of Air. Z. Klin. Chem. Klin. Biochem., 11(3):133-4 (1973) Anon. H Air Pollution - A Hazard for the Present and the Future of Drycleaning. Entetrien des Textiles, p. 29 (1975) (Fre) Anon. H Aliphatic Chlorinated Hydrocarbons and Occupational Health. Groups d'Etude des Nuisances Professionelles. Boulogne, France. 31pp. (1970) Anon. H Danger of Cleaning Solvents. Lancet, 1(7712):1307-8 (June 19, 1971) Anon. H The Dangers of "Safe" Solvents. J. Am. Med. Assoc., 208(8):1484 (1969) Anon. H Detection of Leakages of Perchloroethylene in Dry Cleaning Establishments. Entretien des Textiles, (4):17 (1969) (Fre) Anon. H 'Dry-cleaned' Breast Milk Poisons Baby. Med. World News, (Feb. 20, 1978) Anon. H Editorial; Hazards of Tetrachloroethylene. Arbeitmed. Sozialmed. Praeventivmed., 9(3):59-60 (1974) (Ger) Anon. H Fluorocarbon Solvents in the United States. Tintoreria Lavanderia, 20(9):2 (1971) (Ita) Anon. H Halogen Vapors in Coin Operated Dry Cleaners. Airing., 5(10):20 (Oct. 1963) Anon. H Illnesses among Professionals Caused by Perchloroethylene and Trichloroethylene-Pathology, Regulation, and Prevention. Hebdo Blanchiss. Teintur.7(528):9 (1972) (Fre) 14 ------- Anon. H Methods for the Detection of Toxic Gases in Industry. Organic Halogen Compounds. Department of Scientific and Industrial Research, Leaflet No. 12. pps. 1-6 (1940) Anon. H Ordinance on Dry-Cleaning Installations - 2nd Federal Emissions Protection Ordinance. Inter. Digest Health Legislation, 26(3):552 (1975) Anon. H Perc: A Textbook Chemical Controversy. Daily News Record, 9(42):4 (Mar roversy. . 1979) Anon. H Reagent Hazards. A and R, 16(10):458-63 (1978) (Jpn) Anon. H Recognition and Measuring of Dangerous Gases and Vapors in Industry. Wirkerei Strickerei-Techn., 30(2):112 (Feb. 1980) (Ger) Anon. H Safe Use of Solvents - Chlorinated Hydrocarbons. Health Saf. Work, l(10):31-3 (Jun. 1979) Anon. E San Francisco Bay Area (Air Pollution Trade-Off). J. Air Pollut. Control Assoc., 29(5):544-5 (May 1979) Anon. H Standards of Performance for the Dry Cleaning Industry. Conference: National Air Pollution Control Techniques Advisory Committee. Chicago, IL, Aug. 10-11, 1976. pp. 23-8 (1976) Anon. H Suggestions for the Maximum Allowable Concentration and Other Standards. Sangyo Igaku (Jap. J. Ind. Health), 15(3):60-4 (May 1973) (Jpn) Anon. H Toxic Hazards of Perchloroethylene. Bull. Suppl. Material, CTCP, 9(2):9-14 (1965) Anon. H Toxicity of Tetrachloroethylene. J. Am. Med. Assoc., 131:1468 (Aug. 24, 1946) 15 ------- Anon. H Toxicity of Tetrachloroethylene. J. Am. Med. Assoc., 141(6):426 (1949) Anon. H Two Solvents Cleared As Cancer Threat. Chem. Eng. News, 53(31):7-8 (1975) Anon. H Ventilation and Cooling for Dry Cleaning Establishments. Air Eng., 6(2):39 (FebT 1964) Anon. H What Happened in Providence Valley? An Epidemic? Hysteria? Med. World News, 13(1):18-20 (Mar. 10, 1972) Antoniuzhenko, V.A.; Palkin, B.G. H Clinical Picture and Expert Testimony on Work Capacity in Chronic Occupational Poisoning with Unsaturated and Chlorinated Hydrocarbons. Gig. Tr. Prof. Zabol., 18:16-9 (1973) Apostol, I. H Toxicological Information about Tetrachloroethylene. Munkavedelem, 24(7-9):33-5 (1978) (Hun) Appleby, A. E Atmospheric Freons and Halogenated Compounds. U.S. NTIS, PB-262432, 357 pp. (1976) Appleby, A.; Kazazis, J.; Lillian, D.; et al. E Atmospheric Formation of Chloroform from Trichloroethylene. J. Environ. Sci. Health Part A, All(12):711-5 (1976) Appleby, A.; Lillian, D.; Singh, H.B.; et al. E Letter; Comment on Atmospheric Halocarbons; A Discussion with Emphasis on Chloroform. Geophys. Res. Lett., 3(4):237-8 (Apr. 1976) Arato Sugar, E. Determination of Tetrachloroethylene in Air in the Presence of Trichloroethylene. Munkavedelem, 12(4-6):48-51 (1966) (Hun) Archer, W.L. H Selecting Alternative Chlorinated Solvents. Metal Progr, 1974:133-4 (Oct. 1974) Armand, J.; Evreux, J. H Therapeutic Accident with Didakene. Bull. Med. Leg. Toxicol. Med., 3:138-9 (1971) 16 ------- Asahi Chemical Industry Co., Ltd. Stabilizing Perchloroethylene. Japan, Patent No. 70 39081 Mar. 22, 1967 Asahi Chemical Industry Co., Ltd. Stabilization of Perchloroethylene. Japan, Patent No. 71 05127 Feb. 28, 1968 Asahi Chemical Industry Co., Ltd. Stabilizing Perchloroethylene. Japan, Patent No. 71 05286 May 7, 1968 Asahi Chemical Industry Co., Ltd. Stabilization of Perchloroethylene. Japan, Patent No. 72 42807 May 7, 1968 Asahi Glass Co., Ltd. Stabilization of Tetrachloroethylene. Japan, Patent No. 69 20964 Feb. 10, 1967 Asahi Glass Co., Ltd. Stabilization of Perchloroethylene. Japan, Patent No. 7211046 Jun. 10, 1969 Asahi-Penn Chemical Co., Ltd. E Treatment of Waste Gas from Production of Chlorinated Hydrocarbons by Oxych1orination. Japan, Patent No. 7411773 Jul. 9, 1972 Asano, J.; Ose, Y.; Sato, T.; et al. 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Lav., 51:241 (1960) 137 ------- APPENDICES ------- Appendix I Abstract Collections Manually Searched Source Period of Coverage Chemical Abstracts* (1930-1976) Biological Abstracts* (1930-1970) Excerpta Medica* Physiology, Biochemistry, Pharmacology, (1965-1974) Toxicology Cancer (1953-1974) Public Health, Social Medicine, Hygiene (1955-1974) Clinical Biochemistry (1969-1974) Pharmacology and Toxicology (1969-1974) Occupational Health (1972-1975) Current Contents Life Sciences (Oct. 1979-Mar. 1980) (Apr. 1981-May 1981) Physical Sciences (Oct. 1979-Mar. 1980) (Apr. 1981-May 1981) Agriculture (Oct. 1979-Mar. 1980) (Apr. 1981-May 1981) Industrial Hygiene Digest (1943-1979) Index Medicus* (1930-1976) Toxicology Research Projects Directory (Oct. 1979-Mar. 1980) *Recent issues searched on-line. ------- Appendix II On-Line Databases Searched National Library of Medicine (MEDLARS) File Coverage Period of File + indicates that the database is continually updated. Chemline N/A Toxline 1974+ Toxback 1965-1973 Cancerlit Jan. 1963+ Cancerproj 1976-1978 Medline Jan. 1977+ Back 66 Jan. 1966-Dec. 1968 Back 69 Jan. 1969-Dec. 1971 Back 72 Jan. 1972-Dec. 1974 Back 75 Jan. 1975-Dec. 1976 Toxicology Data Bank N/A Search Strategy RN 127-18-4 ALL tetrachloroethylene (TW) tetrachloroethene ALL perchloroethylene (TW) ankilostin (TW) didakene (TW) ethylene and tetrachloride (TW) nema (TW) persec (TW) tetracap Search Strategy (TW)tetrachlorethylene (TW) perchlorethylene (TW) Antisal (TW) Tetraguer (TW) Fedal and Un (TW) Tetraleno (TW) Tetropil (TW) Perclene (TW) Tetlen All search statements were combined with the logical operator "or" before printout. ------- Appendix II On-Line Databases Searched (cont'd) Lockheed Information Systems (DIALOG) File Coverage Period of File + indicates that the database is continually updated Agricola Air Pollution Technical Information Center Aquatic Sciences and Fisheries Abstracts Biosis Previews Chemical Abstracts Search CA Patent Concordance Commonwealth Agriculture Bureaux Abstracts Chemical Industry Notes Chemname Claims/Chem Comprehensive Dissertation Abstracts Conference Papers Index Current Research Information System EIS Industrial Plants Enviroline Environmental Periodicals Bibliography Excerpta Medica Food Science & Technology Abstracts GPO Monthly Catalog National Technical Information Service Oceanic Abstracts Pollution Abstracts PTS Funk and Scott Indexes PTS Federal Index PTS Annual Time Series PTS US Statistical Abstracts Rubber & Plastics Research Association Abstracts SciSearch Smithsonian Science Information Exchange Current Research Information System Compendex Inspec Metadex Pira Claims /U.S. Patent Claims/U.S. Patent Claims/Class CAB Abstracts Aug. 1971+ 1976-Sep. 1978 Jan. 1975+ 1969+ 1970+ Jan. 1972+ Jan. 1973+ 1974+ N/A 1950-1970 1861+ " 1973+ Jul. 1974+ N/A 1971+ 1973+ Jun. 1974+ 1969+ Jul. 1973+ 1964+ 1964+ 1970+ 1972+ Oct. 1976+ Jul. 1971+ Jul. 1971+ 1972+ Jan. 1974+ Most Recent 2 Yrs, Jul. 1974+ 1970+ 1969+ 1966+ 1975+ Abstracts Weekly 1971 + Oct. 1975+ 1973+ ------- Appendix II On-Line Databases Searched (cont'd) Lockheed Information Systems (DIALOG) Search Strategy tetrachloroetthylene tetra(w)chloroethylene tetra(w)chloro(w)ethylene tetrachloro(w)ethylene tetrachloroethene tetra(w)chloro(w)ethene tetrachloro(w)ethene tetra(w)chloroethene ethylene(w)tetrachloride ethylene(w)tetra(w)chloride ethylene(w)tetrachloro ethylene(w)tetra(w)chloro ethene(w)tetrachloro ethene(w)tetra(w)chloro l(w)l(w)2(w)2(w)tetrachloroethylene l(w)l(w)2(w)2(w)tetrachloro(w)ethylene l(w)l(w)2(w)2(w)tetra(w)chloroethylene l(w)l(w)2(w)2(w)tetra(w)chloro(w)ethylene perchloroethylene Search Stragety perchloro(w)ethylene per(w)chloro(w)ethylene Ankilostin Didakeen Nema Persec Per(w)sec Tetracap Tetra(w)cap Antisal(w)! Antisal Tetraguer Fedal(w)un Tetraleno Tetropil Perclene Tetlen RN 127-18-4 used in appropriate files ------- Database Appendix II On-Line Databases Searched (cont'd) Systems Development Corporation (ORBIT) Coverage Period of File + indicates that the database is continually updated. Apilit Apipat Chemdex Crecord Fedreg Grants Paperchem Safety Science Titus Search Strategy (RN)127-18-4 (in appropriate files) tetrachloroethylene tetrachloroethene perchloroethylene Ankilostin Didakene ethylene and tetrachloride Nema Persec Tetracap 1974+ 1964+ 1972+ 1976+ Mar. 1977+ 1977+ 1968+ Jun. 1975+ 1970+ Search Strategy perchlorethylene Antisal Tetraguer Fedal and Un Tetraleno Tetropil Perclene Tetlen All search statements were combined with the logical operator "or" before printout. ------- Appendix II On-Line Databases Searched (cont'd) Department of Energy (RECON) File Coverage Period of File + indicates that the database is continually updated. Water Resources Abstracts 1968+ Environmental Mutagen Information Center 1969+ Environmental Teratogen Information Center 1975+ Search Strategy IT= tetrachloroethylene RN= 127-18-4 Chemical Information System* Structure and Nomenclature Search System (SANSS) (RN) 127-18-4 *Searched to obtain synonyms only National Institute for Occupational Safety and Health NIOSHTIC 1973+ + indicates that the database is continually updated. Search Strategy trichloroethylene 127-18-4 ------- |